CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP028333	Listeria monocytogenes strain CFSAN054108 chromosome, complete genome	3 crisprs	DinG,csa3,WYL,cas3,DEDDh,casR	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP028333_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028333_1

138780-138934

Unclear

Consensus_repeat	Method
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP028333_1

>merge|NZ_CP028333|1|138780-138934|CRISPRCasFinder
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAATTCGAATGAGCTCGGTTCCGATGTAGCAGGAGCATTAAAACCAAGAAGCATCGGTGTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAA

>NZ_CP028333|1|1|138780-138934|CRISPRCasFinder
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAA	TTCGAATGAGCTCGGTTCCGATGTAGCAGGAGCATTAAAACCAAGAAGCATCGGT
GTCTCTGGCAAAGCAAGTCTTAACTCTTCATCCGTAGGTGGTGGTGGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028333.1\|WP_003722725.1\|148801_149110_-\|septation-protein-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP028333.1\|WP_003725734.1\|135912_136374_-\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NZ_CP028333.1\|WP_003725735.1\|135527_135860_+\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NZ_CP028333.1\|WP_003728174.1\|141792_143382_-\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NZ_CP028333.1\|WP_003722740.1\|132850_133474_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP028333.1\|WP_003722729.1\|144850_145564_+\|listeriolysin-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736
NZ_CP028333.1\|WP_003734712.1\|136901_137771_-\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NZ_CP028333.1\|WP_003734710.1\|146614_147988_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_CP028333.1\|WP_003725738.1\|131509_132070_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP028333.1\|WP_003725730.1\|139925_141458_-\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NZ_CP028333.1\|WP_003726703.1\|143624_144578_+\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NZ_CP028333.1\|WP_003722728.1\|145607_146564_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP028333.1\|WP_003725507.1\|149793_151002_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|182528
NZ_CP028333.1\|WP_003725737.1\|132176_132761_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP028333.1\|WP_003722723.1\|150998_151691_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP028333.1\|WP_003725736.1\|134729_135461_+\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_CP028333.1\|WP_003734713.1\|136506_136830_-\|DUF5502-family-protein	unknown	unknown	gnl\|CDD\|340321
NZ_CP028333.1\|WP_003722726.1\|148374_148683_-\|septation-protein-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP028333.1\|WP_003728167.1\|127856_131396_-\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_CP028333.1\|WP_003722739.1\|133767_134709_+\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836

Protein	Function_ID	Function_description	E-value
NZ_CP028333.1\|WP_003722725.1\|148801_149110_-\|septation-protein-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NZ_CP028333.1\|WP_003725734.1\|135912_136374_-\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	1.52192e-59
NZ_CP028333.1\|WP_003725735.1\|135527_135860_+\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NZ_CP028333.1\|WP_003728174.1\|141792_143382_-\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	7.22171e-179
NZ_CP028333.1\|WP_003722740.1\|132850_133474_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NZ_CP028333.1\|WP_003722729.1\|144850_145564_+\|listeriolysin-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12
NZ_CP028333.1\|WP_003734712.1\|136901_137771_-\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	6.38793e-86
NZ_CP028333.1\|WP_003734710.1\|146614_147988_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP028333.1\|WP_003725738.1\|131509_132070_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	1.72721e-108
NZ_CP028333.1\|WP_003725730.1\|139925_141458_-\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	3.62455e-140
NZ_CP028333.1\|WP_003726703.1\|143624_144578_+\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	1.53279e-112
NZ_CP028333.1\|WP_003722728.1\|145607_146564_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP028333.1\|WP_003725507.1\|149793_151002_-\|FtsX-like-permease-family-protein	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.06393e-62
NZ_CP028333.1\|WP_003725737.1\|132176_132761_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.9401e-09
NZ_CP028333.1\|WP_003722723.1\|150998_151691_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121
NZ_CP028333.1\|WP_003725736.1\|134729_135461_+\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	1.88663e-21
NZ_CP028333.1\|WP_003734713.1\|136506_136830_-\|DUF5502-family-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	1.23896e-43
NZ_CP028333.1\|WP_003722726.1\|148374_148683_-\|septation-protein-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NZ_CP028333.1\|WP_003728167.1\|127856_131396_-\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_CP028333.1\|WP_003722739.1\|133767_134709_+\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0

>NZ_CP028333.1|WP_003734712.1|136901_137771_-|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPVTIKASACCDEYLKPPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVDHMRANLMNELKNFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDKDNTYLPGFANAKITGAKYFNQSVADYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVVKRFCSNDVKEWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NZ_CP028333.1|WP_003734713.1|136506_136830_-|DUF5502-family-protein
MYIKGGLIFFFVMFVIALCSVLILLIIKMSVWKEEPFNLSDAKEIECLGSCKIKNTNQKIHFFSIKKNLFEEEGNMAGILNEHERKGADKSIFIVILDDEKGIANEE
>NZ_CP028333.1|WP_003725734.1|135912_136374_-|YehR-family-lipoprotein
MKMLKKGTTVLFVMIMAVMLVACGDKEETKTYSLSQNGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NZ_CP028333.1|WP_003725735.1|135527_135860_+|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NZ_CP028333.1|WP_003725736.1|134729_135461_+|DNA-alkylation-repair-protein
MRLRMLFLLYLIYSRGVTRTITFDQLNTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVELIESNNSDLIYLGLLAINPDKITTEQIEKWNIIFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAEALLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NZ_CP028333.1|WP_003722739.1|133767_134709_+|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NZ_CP028333.1|WP_003722740.1|132850_133474_-|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NZ_CP028333.1|WP_003725737.1|132176_132761_-|GNAT-family-N-acetyltransferase
MLDKSVPHISAIMVNHDATNYPEFHLPEGYSFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLAKRCVFVEAPNGEIIGTAMLWDGNTFGEMASRIHWVAVLDSHGGKGIAKALLSKILGLNKSSFVYLTTQTGSYQAIYLYQKFGFEKYVGKTPENWKTVNFQEEKEAAWQIIENKIAEHQA
>NZ_CP028333.1|WP_003725738.1|131509_132070_-|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVIHYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NZ_CP028333.1|WP_003728167.1|127856_131396_-|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMTHTLNELKENEDKQALVENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYFPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEANHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVHALEVGIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKERASAEN
>NZ_CP028333.1|WP_003725730.1|139925_141458_-|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFNMAVKADSVGEERLRNNIQAKRNPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSDGYLTDNDEIKVHVTPDNKIAFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYIGNPVKEKEIIINSRTKRLVYNIKLIFAEPEVASWIIQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLNHKTDASFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYDYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGREILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGLRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHFNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKAQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NZ_CP028333.1|WP_003728174.1|141792_143382_-|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENLISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEINYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNSVDNPIE
>NZ_CP028333.1|WP_003726703.1|143624_144578_+|phosphatidylinositol-specific-phospholipase-C
MYKNYLQRTLVLVLCFILCFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTSLAALSIPGTHDTMSYNGDMTWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLKIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSHKFGMQFGASNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NZ_CP028333.1|WP_003722729.1|144850_145564_+|listeriolysin-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NZ_CP028333.1|WP_003722728.1|145607_146564_-|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NZ_CP028333.1|WP_003734710.1|146614_147988_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQEEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASRLMQRRINENHMRNGVTLVNPENTYIDIDVKIGQDTVIEPGVMLRGETVIGDDCVVTTGSEIVNSVIGERVYVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPDDALGIARAKQDNKLGYAKHLNHGK
>NZ_CP028333.1|WP_003722726.1|148374_148683_-|septation-protein-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NZ_CP028333.1|WP_003722725.1|148801_149110_-|septation-protein-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NZ_CP028333.1|WP_003725507.1|149793_151002_-|FtsX-like-permease-family-protein
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NZ_CP028333.1|WP_003722723.1|150998_151691_-|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA

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Crispr_ID: NZ_CP028333_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028333_2

2818466-2819050

Orphan

Consensus_repeat	Method
CATATNAGTTACTGAACTNGTATCAAAATTACTTACATC	CRT

7 spacers

The CRISPR arrays of NZ_CP028333_2

>merge|NZ_CP028333|2|2818466-2819050|CRT
CATGTTAGTCACTGAACTGGTATCAAAGGTACTTAAATCAAGCTTCTCCAGTTTTTCATTATCAGAAAACATGGCAGCCATATTAGTTACTGAACTCGTATCAAAATTACTTACATCTAACGCTTCAAGACTAGTACAACCAGCAAACATGGCACGCATATCAGTTACTAAGCTCGTATTAAAATTACTTACATCCAACTTCTCAAGGGCGCTACAATTTCTAAACATTTGAACCATTTCAGTAGCGGAACTGGTATCGAAATTACTTACATCTAGTTTCTTCAGTTTTTCACAGCCATTAAACACTCTATACATATCAGTTACTGAACTCGTATCAAAATTACTTACATCCAGCTCTTCAAGACTAGTACAATCTTCAAACATGGCATACATATTAGTTACTGAACTCGTATCAAGGTTGCTTACATCCAGCACCTCAAGGTTTCTATTATCATAAAACATGTAAGACATATTAGTTACTGAACTCGTATCAAAATGACTTACATCCAGTTCCTCAAGTGCCCTACAGCTGTTAAACATATCCCACATAGTAGTTACCGCACTAGTATCAAGACCACTCAAATC

>NZ_CP028333|2|1|2818466-2819050|CRT
CATGTTAGTCACTGAACTGGTATCAAAGGTACTTAAATC	AAGCTTCTCCAGTTTTTCATTATCAGAAAACATGGCAGC
CATATTAGTTACTGAACTCGTATCAAAATTACTTACATC	TAACGCTTCAAGACTAGTACAACCAGCAAACATGGCACG
CATATCAGTTACTAAGCTCGTATTAAAATTACTTACATC	CAACTTCTCAAGGGCGCTACAATTTCTAAACATTTGAAC
CATTTCAGTAGCGGAACTGGTATCGAAATTACTTACATC	TAGTTTCTTCAGTTTTTCACAGCCATTAAACACTCTATA
CATATCAGTTACTGAACTCGTATCAAAATTACTTACATC	CAGCTCTTCAAGACTAGTACAATCTTCAAACATGGCATA
CATATTAGTTACTGAACTCGTATCAAGGTTGCTTACATC	CAGCACCTCAAGGTTTCTATTATCATAAAACATGTAAGA
CATATTAGTTACTGAACTCGTATCAAAATGACTTACATC	CAGTTCCTCAAGTGCCCTACAGCTGTTAAACATATCCCA
CATAGTAGTTACCGCACTAGTATCAAGACCACTCAAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028333.1\|WP_003734632.1\|2834311_2835067_+\|DUF4866-family-protein	unknown	unknown	gnl\|CDD\|379782
NZ_CP028333.1\|WP_003740428.1\|2828187_2829783_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP028333.1\|WP_003721242.1\|2829938_2830886_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP028333.1\|WP_003734633.1\|2832035_2834195_+\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP028333.1\|WP_003734774.1\|2813263_2813506_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_020830750.1\|2815918_2816185_-\|transposase	unknown	unknown	unknown
NZ_CP028333.1\|WP_010958986.1\|2816593_2817079_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_014929030.1\|2819842_2821690_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP028333.1\|WP_012681110.1\|2810614_2811442_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573
NZ_CP028333.1\|WP_003727314.1\|2810227_2810587_-\|DUF3139-domain-containing-protein	unknown	unknown	gnl\|CDD\|371476
NZ_CP028333.1\|WP_003734772.1\|2814565_2815183_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_014929029.1\|2821953_2823492_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP028333.1\|WP_003721252.1\|2817098_2817572_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_003740435.1\|2816260_2816566_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP028333.1\|WP_003734634.1\|2830890_2832039_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP028333.1\|WP_003728092.1\|2824125_2825676_-\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP028333.1\|WP_003728093.1\|2825668_2826769_-\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP028333.1\|WP_003734776.1\|2809341_2809902_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_CP028333.1\|WP_003725189.1\|2826769_2828053_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP028333.1\|WP_003734775.1\|2812203_2813181_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004

Protein	Function_ID	Function_description	E-value
NZ_CP028333.1\|WP_003740435.1\|2816260_2816566_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.51255e-05
NZ_CP028333.1\|WP_003734633.1\|2832035_2834195_+\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.58381e-28
NZ_CP028333.1\|WP_003721242.1\|2829938_2830886_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP028333.1\|WP_014929030.1\|2819842_2821690_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	8.47304e-32
NZ_CP028333.1\|WP_012681110.1\|2810614_2811442_-\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	0.00019582
NZ_CP028333.1\|WP_003740428.1\|2828187_2829783_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP028333.1\|WP_014929029.1\|2821953_2823492_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	9.23286e-20
NZ_CP028333.1\|WP_003728092.1\|2824125_2825676_-\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_CP028333.1\|WP_003727314.1\|2810227_2810587_-\|DUF3139-domain-containing-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	1.02958e-22
NZ_CP028333.1\|WP_003734634.1\|2830890_2832039_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.03616e-53
NZ_CP028333.1\|WP_003734632.1\|2834311_2835067_+\|DUF4866-family-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
NZ_CP028333.1\|WP_003734775.1\|2812203_2813181_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	3.2717e-43
NZ_CP028333.1\|WP_003734776.1\|2809341_2809902_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	1.62467e-24
NZ_CP028333.1\|WP_003725189.1\|2826769_2828053_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP028333.1\|WP_003728093.1\|2825668_2826769_-\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0

>NZ_CP028333.1|WP_003721252.1|2817098_2817572_-|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP028333.1|WP_010958986.1|2816593_2817079_-|hypothetical-protein
MNKLVLSTLSVAAMGMVIFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP028333.1|WP_003740435.1|2816260_2816566_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP028333.1|WP_020830750.1|2815918_2816185_-|transposase
MARIEYGEEIQKSLLVLYSRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQVRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP028333.1|WP_003734772.1|2814565_2815183_-|hypothetical-protein
MLMSLSVLPLATYASETENTPTESYDGENFIATQTGNTLVIEDKKTGETVKIEMNDEENGVITSDDGTIENVHRDEEGNVYVDNELELEAPPLDIEDGINIATQPRLLKASKWIYVQTTKYNTTTQGNMRSLALGILSFMPITGPIFGIVAIIDAARSMGAKTLYVRVKQYRTSGYQFYKYDSYYYANASLTKLVKKTSQTKRMW
>NZ_CP028333.1|WP_003734774.1|2813263_2813506_-|hypothetical-protein
MKRIILTSTLIVWTIVCIYMSISMVSNNTGIAFPIWLHIILLICFLATGIVNVKKKEYLWSTMLFEGVLVVLLSLIIVLV
>NZ_CP028333.1|WP_003734775.1|2812203_2813181_+|HD-domain-containing-protein
MKITDPLYGTFEIEPVLAELIQSPLVSRLAYVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFDDISKWKILEQEAPELCADRIDYTLQDLYRHRKISLAEVEEFLQALVMVDGRLYLANIALAEWFVAQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITTADLRLTDTELLAKLNANSDAREKIQLLASAHLEENEADFTYHHKKKMRLINPSILVDGRLIPADELSEKVRKMNDWASERSKHGIYIKATKKSKQ
>NZ_CP028333.1|WP_012681110.1|2810614_2811442_-|hypothetical-protein
MKKRLIGIITALLLVSGILLSPQMAQAETKVDYDALYQQGVSEGIINKADVSLETWIKENESEYNQVYQDGLKDGVYDASLSYEEWIKLNNYGQPPVVDENWEEVPQKPMLKGVYKGYNIKKGDILITNGTSSSGLLGHAAIANGNEYILDIPGAGKTTRQVPTSKWMSDYDPEGWVKVYRLKDSSVANAAANWADKNYYSTKGTSKQNIFPKYGMTGSRYSKNPTYCSKIVLQAYYFGTGNKPVVQVFPSLVTVYDLPNYFSKAYKPQQVKYFK
>NZ_CP028333.1|WP_003727314.1|2810227_2810587_-|DUF3139-domain-containing-protein
MKKYKKWWITIGLVLIICIIGYIYWFAIPKHTANEAVDDYLAAQKINSTQVKTRDIQKDWTRGGYYVTIVFKDDPNLVYEYNYNSKRNTPYHINLLVFKDGSSQEDDQVKHPPLQEQKD
>NZ_CP028333.1|WP_003734776.1|2809341_2809902_-|TetR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLENWDKHVLKMLESIKENDDFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_CP028333.1|WP_014929030.1|2819842_2821690_-|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSDVITEGVPQEKPAEAENLEEIPTTDELMQNPNVLERSVADSDDSDLTVVSSGAYWTLYYNSANGEYSLRMFGNVPSSRPTAWNNYLKRIKHIEIEEATLTGDFVGYFGWFIGLKGVRIEGSDLSGVTSFQQAFSNSSLEKVIIKNNYYSNSQSLTNTKQMFFMAKNLSELDLSGLNTSFVTTMERMFEGCENLKILNLSNFDFDTSSVINMDYMFADCTNLEELDVSKFDTSSVTFMQMMFQYCKSLEKLNLSSFDTSSVTRMNSMFEGCTSFEELDLSSFDTSSVGNMQTMFQGCTNLKVLYLDKFDDNITTNKNNMFGNTPLLSYLRFSHRFTKLENIGLENTNWYDEKNWVQFSNITQLQTYNKQQSEPTGYRKGAFFSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEASELKVEGINRGGKTLSVGLNYGKTTISESNKLTLSNTADTTVQCLAPLSWDGSETNPKNAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSVNYE
>NZ_CP028333.1|WP_014929029.1|2821953_2823492_-|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLSSFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNNNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLTSDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEILNQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>NZ_CP028333.1|WP_003728092.1|2824125_2825676_-|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP028333.1|WP_003728093.1|2825668_2826769_-|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP028333.1|WP_003725189.1|2826769_2828053_-|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP028333.1|WP_003740428.1|2828187_2829783_-|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP028333.1|WP_003721242.1|2829938_2830886_+|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP028333.1|WP_003734634.1|2830890_2832039_+|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLVDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP028333.1|WP_003734633.1|2832035_2834195_+|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVALLALVIIFRRRIRSYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFGTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP028333.1|WP_003734632.1|2834311_2835067_+|DUF4866-family-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK

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Crispr_ID: NZ_CP028333_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028333_3

2820696-2820874

Orphan

Consensus_repeat	Method
GAACTCGTATCAAAACTGCTTAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP028333_3

>merge|NZ_CP028333|3|2820696-2820874|CRISPRCasFinder
GAACTCGTATCAAAACTGCTTAAGTCTAGCTCTTCAAAACTAGTACATCCTTCAAACATACTATTCATGCGAGTTACTGAGCTCGTATCAAAACTGCTTAAATTCAGTTTCTCAAGCGATTTACAATATTGAAACATCATCTGCATAAAAGTAACAGAGCTGGTATCAAATTTGCTTAC

>NZ_CP028333|3|2|2820696-2820874|CRISPRCasFinder
GAACTCGTATCAAAACTGCTTAA	GTCTAGCTCTTCAAAACTAGTACATCCTTCAAACATACTATTCATGCGAGTTACT
GAGCTCGTATCAAAACTGCTTAA	ATTCAGTTTCTCAAGCGATTTACAATATTGAAACATCATCTGCATAAAAGTAACA
GAGCTGGTATCAAATTTGCTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028333.1\|WP_003734633.1\|2832035_2834195_+\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP028333.1\|WP_003721242.1\|2829938_2830886_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP028333.1\|WP_003734774.1\|2813263_2813506_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_020830750.1\|2815918_2816185_-\|transposase	unknown	unknown	unknown
NZ_CP028333.1\|WP_010958986.1\|2816593_2817079_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_003740435.1\|2816260_2816566_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP028333.1\|WP_003734991.1\|2817637_2819707_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP028333.1\|WP_003740428.1\|2828187_2829783_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP028333.1\|WP_003734772.1\|2814565_2815183_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_014929029.1\|2821953_2823492_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP028333.1\|WP_003725184.1\|2835087_2835753_+\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|226146
NZ_CP028333.1\|WP_003721252.1\|2817098_2817572_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028333.1\|WP_003725189.1\|2826769_2828053_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP028333.1\|WP_003727314.1\|2810227_2810587_-\|DUF3139-domain-containing-protein	unknown	unknown	gnl\|CDD\|371476
NZ_CP028333.1\|WP_003734634.1\|2830890_2832039_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP028333.1\|WP_003728092.1\|2824125_2825676_-\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP028333.1\|WP_003728093.1\|2825668_2826769_-\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP028333.1\|WP_003734632.1\|2834311_2835067_+\|DUF4866-family-protein	unknown	unknown	gnl\|CDD\|379782
NZ_CP028333.1\|WP_012681110.1\|2810614_2811442_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573
NZ_CP028333.1\|WP_003734775.1\|2812203_2813181_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004

Protein	Function_ID	Function_description	E-value
NZ_CP028333.1\|WP_012681110.1\|2810614_2811442_-\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	0.00019582
NZ_CP028333.1\|WP_003721242.1\|2829938_2830886_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP028333.1\|WP_003734633.1\|2832035_2834195_+\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.58381e-28
NZ_CP028333.1\|WP_003725184.1\|2835087_2835753_+\|DUF1275-domain-containing-protein	gnl\|CDD\|226146	COG3619, COG3619, Predicted membrane protein [Function unknown].	1.87997e-68
NZ_CP028333.1\|WP_003740435.1\|2816260_2816566_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.51255e-05
NZ_CP028333.1\|WP_003725189.1\|2826769_2828053_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP028333.1\|WP_003740428.1\|2828187_2829783_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP028333.1\|WP_014929029.1\|2821953_2823492_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	9.23286e-20
NZ_CP028333.1\|WP_003728092.1\|2824125_2825676_-\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_CP028333.1\|WP_003727314.1\|2810227_2810587_-\|DUF3139-domain-containing-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	1.02958e-22
NZ_CP028333.1\|WP_003734634.1\|2830890_2832039_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.03616e-53
NZ_CP028333.1\|WP_003734775.1\|2812203_2813181_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	3.2717e-43
NZ_CP028333.1\|WP_003734632.1\|2834311_2835067_+\|DUF4866-family-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
NZ_CP028333.1\|WP_003734991.1\|2817637_2819707_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.65689e-31
NZ_CP028333.1\|WP_003728093.1\|2825668_2826769_-\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0

>NZ_CP028333.1|WP_003734991.1|2817637_2819707_-|BspA-family-leucine-rich-repeat-surface-protein
MKKLSMRVILIVTVIFIAFGSANVSIAQERDTINKLPEVELGSLYTSNLITEEVAQDKPAEVENLEEAPTTDDLVQNPDVLEQLIADSDDSDLTVVNSGDFWTIYRNTVNGEYSLHMFGNVPSSKPTAWNSYLNRIKHIEIEEATLTGNFSSYFRNNVFTVLESVRIERSNLSRVTSFALAFYGSGIEKVIIRDNNYPTAPSLLTTEGMFKNCSNLMEVDLSGLDTSAVTTMWDMFNSCRALEELDVSHFDTSSVTNMSYMFYDNRNLEVLDVSNLDTSSVTNMYAMFEDCTSLEELDVSNFDTSSVTDMYRVFNGCEKLKKLDVSNFDTSSATEMVQMFRNCSALEKLDVSNFNTSLVTDMRAMFAGCTSLEALDVSNFDTSSVTNMAAMFSDNEKLEKLDLSTFDTSSVTNMGTMFKNCTALKSLFLDNFTHAASSTDMFTGTTSLTYLFVSHNVSNFNGLENTSWYDEKNWVQFSNLSQLQTYHRQQSEPIGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEASELKVQGINRGSKTLSVGLNYEETTISESNKLTLANTADTTVQCLAPLSWDGSETNPEKAILTLAPGSEITEGEAVMVIEAPENIQAGKYTGNVVFSIKYE
>NZ_CP028333.1|WP_003721252.1|2817098_2817572_-|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP028333.1|WP_010958986.1|2816593_2817079_-|hypothetical-protein
MNKLVLSTLSVAAMGMVIFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP028333.1|WP_003740435.1|2816260_2816566_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP028333.1|WP_020830750.1|2815918_2816185_-|transposase
MARIEYGEEIQKSLLVLYSRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQVRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP028333.1|WP_003734772.1|2814565_2815183_-|hypothetical-protein
MLMSLSVLPLATYASETENTPTESYDGENFIATQTGNTLVIEDKKTGETVKIEMNDEENGVITSDDGTIENVHRDEEGNVYVDNELELEAPPLDIEDGINIATQPRLLKASKWIYVQTTKYNTTTQGNMRSLALGILSFMPITGPIFGIVAIIDAARSMGAKTLYVRVKQYRTSGYQFYKYDSYYYANASLTKLVKKTSQTKRMW
>NZ_CP028333.1|WP_003734774.1|2813263_2813506_-|hypothetical-protein
MKRIILTSTLIVWTIVCIYMSISMVSNNTGIAFPIWLHIILLICFLATGIVNVKKKEYLWSTMLFEGVLVVLLSLIIVLV
>NZ_CP028333.1|WP_003734775.1|2812203_2813181_+|HD-domain-containing-protein
MKITDPLYGTFEIEPVLAELIQSPLVSRLAYVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFDDISKWKILEQEAPELCADRIDYTLQDLYRHRKISLAEVEEFLQALVMVDGRLYLANIALAEWFVAQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITTADLRLTDTELLAKLNANSDAREKIQLLASAHLEENEADFTYHHKKKMRLINPSILVDGRLIPADELSEKVRKMNDWASERSKHGIYIKATKKSKQ
>NZ_CP028333.1|WP_012681110.1|2810614_2811442_-|hypothetical-protein
MKKRLIGIITALLLVSGILLSPQMAQAETKVDYDALYQQGVSEGIINKADVSLETWIKENESEYNQVYQDGLKDGVYDASLSYEEWIKLNNYGQPPVVDENWEEVPQKPMLKGVYKGYNIKKGDILITNGTSSSGLLGHAAIANGNEYILDIPGAGKTTRQVPTSKWMSDYDPEGWVKVYRLKDSSVANAAANWADKNYYSTKGTSKQNIFPKYGMTGSRYSKNPTYCSKIVLQAYYFGTGNKPVVQVFPSLVTVYDLPNYFSKAYKPQQVKYFK
>NZ_CP028333.1|WP_003727314.1|2810227_2810587_-|DUF3139-domain-containing-protein
MKKYKKWWITIGLVLIICIIGYIYWFAIPKHTANEAVDDYLAAQKINSTQVKTRDIQKDWTRGGYYVTIVFKDDPNLVYEYNYNSKRNTPYHINLLVFKDGSSQEDDQVKHPPLQEQKD
>NZ_CP028333.1|WP_014929029.1|2821953_2823492_-|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLSSFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNNNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLTSDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEILNQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>NZ_CP028333.1|WP_003728092.1|2824125_2825676_-|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP028333.1|WP_003728093.1|2825668_2826769_-|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP028333.1|WP_003725189.1|2826769_2828053_-|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP028333.1|WP_003740428.1|2828187_2829783_-|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP028333.1|WP_003721242.1|2829938_2830886_+|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP028333.1|WP_003734634.1|2830890_2832039_+|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLVDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP028333.1|WP_003734633.1|2832035_2834195_+|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVALLALVIIFRRRIRSYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFGTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP028333.1|WP_003734632.1|2834311_2835067_+|DUF4866-family-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NZ_CP028333.1|WP_003725184.1|2835087_2835753_+|DUF1275-domain-containing-protein
MARSRQISESIGLGLLLALAGGFMDAYSYIERGQVFANAQTGNILLFGINISEGNWAIAIQYFWPVVSFTVGIAISEVIHRRDIRRLHWRQLSVLIEAVILIGVAFIPLDHNLIANSLISFVCGIQVESFRKMHGRGVATTMCIGNLRSATQNLCDYFEYKEKQYLRNSLLYFTVILSFIIGAVVGNFFIQLFAQYAILVCAFLQFIAFMMMFIDRESKII

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

215650 : 301466

105

Listeria_phage(86.76%)

holin,plate,capsid,integrase,tail,terminase,transposase

attL 263089:263133|attR 300348:300392

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003734720.1\|215650_216469_-\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0
WP_003731178.1\|216465_218334_-	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_003740367.1\|218320_218725_-	hypothetical protein	NA	NA	NA	NA
WP_003721745.1\|218766_219069_-	hypothetical protein	NA	NA	NA	NA
WP_003721744.1\|219116_219629_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003728212.1\|219641_220031_-	DUF5072 domain-containing protein	NA	NA	NA	NA
WP_003728213.1\|220310_220727_-	hypothetical protein	A8ASQ1	Listeria_phage	3.2e-19	37.9
WP_003724946.1\|220738_221167_-	hypothetical protein	NA	NA	NA	NA
WP_003721740.1\|221383_221719_+	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003728215.1\|221724_222177_+	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003724944.1\|222395_223091_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003724943.1\|223060_223768_-	EAL domain-containing protein	NA	NA	NA	NA
WP_003734721.1\|223874_224990_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003724941.1\|225024_225858_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_003724940.1\|226000_227743_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.1e-55	30.1
WP_003734722.1\|227735_229517_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.3e-53	30.8
WP_003735019.1\|229640_231038_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-118	50.0
WP_003734723.1\|231088_231991_-	ROK family protein	NA	NA	NA	NA
WP_003734724.1\|232093_234364_-	chitinase	A0A2K9L3D4	Tupanvirus	7.6e-38	32.1
WP_003724936.1\|234654_235026_-	hypothetical protein	NA	NA	NA	NA
WP_107131774.1\|235121_235754_-	nitroreductase family protein	NA	NA	NA	NA
WP_003742434.1\|235767_236058_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003724933.1\|236169_236463_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003734725.1\|236577_238095_+	pyruvyl transferase	NA	NA	NA	NA
WP_003721726.1\|238135_238486_-	DUF2200 domain-containing protein	NA	NA	NA	NA
WP_003728363.1\|238619_239009_-	DUF956 family protein	NA	NA	NA	NA
WP_003721724.1\|239135_240047_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_003724931.1\|240068_240875_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_003721722.1\|240898_241864_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_003728364.1\|242161_242794_-	hypothetical protein	NA	NA	NA	NA
WP_003724929.1\|242968_243529_-	hypothetical protein	NA	NA	NA	NA
WP_003724928.1\|243509_243842_-	hypothetical protein	NA	NA	NA	NA
WP_003724927.1\|243854_245225_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_003724926.1\|245225_246095_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_003728365.1\|246091_247588_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_012681011.1\|247584_248616_-	ATP synthase F1 subunit delta	NA	NA	NA	NA
WP_003721714.1\|248627_248870_-	ATP synthase F0 subunit C	NA	NA	NA	NA
WP_003728367.1\|248926_251236_-	hypothetical protein	NA	NA	NA	NA
WP_003734727.1\|251232_257112_-	hypothetical protein	NA	NA	NA	NA
WP_003724921.1\|257188_257878_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003734728.1\|258268_259252_+	aldo/keto reductase	NA	NA	NA	NA
WP_003724919.1\|259307_259676_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003724918.1\|259742_260084_-	hypothetical protein	NA	NA	NA	NA
WP_003724917.1\|260209_260554_-	hypothetical protein	NA	NA	NA	NA
WP_003724916.1\|261026_261404_-	hypothetical protein	NA	NA	NA	NA
WP_003734729.1\|261385_262909_-	hypothetical protein	NA	NA	NA	NA
263089:263133	attL	NA	NA	NA	NA
WP_069001825.1\|263232_263439_-	hypothetical protein	A8ASL9	Listeria_phage	8.7e-26	79.4
WP_003731278.1\|263435_263669_-	hypothetical protein	R4IDW6	Listeria_phage	3.6e-36	97.4
WP_003734985.1\|263905_264298_-	hypothetical protein	A8ATC1	Listeria_phage	5.1e-67	100.0
WP_015987299.1\|264294_264798_-	DUF4065 domain-containing protein	A8ATC0	Listeria_phage	7.0e-93	100.0
WP_003734987.1\|265200_266127_-	N-acetylmuramoyl-L-alanine amidase family protein	R4ICC5	Listeria_phage	9.9e-170	92.2
WP_031644824.1\|266128_266362_-	hypothetical protein	R4IBI3	Listeria_phage	1.7e-33	92.2
WP_031644822.1\|266358_266643_-\|holin	holin	R4IDW2	Listeria_phage	5.7e-44	98.9
WP_003725053.1\|266655_267021_-	hypothetical protein	A8ASL3	Listeria_phage	1.3e-11	100.0
WP_003725054.1\|267057_267204_-	XkdX family protein	A8ASL2	Listeria_phage	1.1e-19	100.0
WP_061729023.1\|267204_267546_-	hypothetical protein	A0A059T7P5	Listeria_phage	2.3e-55	95.6
WP_061729022.1\|267542_268610_-\|plate	BppU family phage baseplate upper protein	A0A0B5D119	Listeria_phage	1.7e-157	83.9
WP_010991151.1\|268606_269635_-	hypothetical protein	A0A0B5D0C2	Listeria_phage	2.2e-194	100.0
WP_003740854.1\|269631_270645_-	hypothetical protein	A0A0B5CYL4	Listeria_phage	1.2e-187	100.0
WP_003725059.1\|270657_271482_-\|tail	phage tail family protein	A0A0B5CTY7	Listeria_phage	5.9e-158	100.0
WP_107131775.1\|271485_276291_-\|tail	phage tail tape measure protein	A0A0B5CTS6	Listeria_phage	0.0e+00	88.7
WP_072218650.1\|276295_276607_-	hypothetical protein	A0A0B5D116	Listeria_phage	1.2e-42	98.9
WP_107131776.1\|276603_277035_-	hypothetical protein	A0A0B5D0B8	Listeria_phage	3.2e-70	95.1
WP_003734903.1\|277084_277771_-	Ig domain-containing protein	A8ATV6	Listeria_phage	2.7e-108	92.1
WP_003725064.1\|277775_278147_-	hypothetical protein	A8ATV5	Listeria_phage	8.5e-64	100.0
WP_003734904.1\|278143_278461_-	HK97 gp10 family phage protein	A8ATV4	Listeria_phage	2.5e-48	93.3
WP_003734905.1\|278450_278816_-	hypothetical protein	A8ATV3	Listeria_phage	8.4e-64	97.5
WP_070238329.1\|278815_279169_-	hypothetical protein	A8ATV2	Listeria_phage	4.2e-60	98.3
WP_070238330.1\|279350_280223_-	hypothetical protein	A8ATV0	Listeria_phage	1.4e-160	99.0
WP_070238331.1\|280245_280800_-	hypothetical protein	A8ATU9	Listeria_phage	6.3e-87	97.3
WP_070238332.1\|280895_281939_-\|capsid	minor capsid protein	A0A0B5D111	Listeria_phage	2.0e-198	98.6
WP_031648715.1\|281943_283500_-	hypothetical protein	A8ATU7	Listeria_phage	6.5e-299	98.6
WP_077955358.1\|283514_284834_-\|terminase	PBSX family phage terminase large subunit	A0A0B5CYJ6	Listeria_phage	9.9e-264	98.9
WP_107131777.1\|284826_285567_-	TerS	A8ATU5	Listeria_phage	7.0e-134	98.8
WP_003725074.1\|285606_285834_-	hypothetical protein	A0A0B5CTV3	Listeria_phage	1.8e-32	94.7
WP_003734998.1\|286095_286668_-	sigma-70 family RNA polymerase sigma factor	A0A0B5CTZ3	Listeria_phage	7.9e-85	82.1
WP_003734997.1\|286757_286913_-	hypothetical protein	A0A0B5D186	Listeria_phage	7.5e-22	96.1
WP_003734996.1\|286953_287337_-	DUF2481 family protein	A8ASP8	Listeria_phage	2.9e-35	56.7
WP_010991162.1\|287340_287745_-	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	1.7e-57	83.6
WP_031669404.1\|287689_287872_-	hypothetical protein	A8ASP6	Listeria_phage	2.2e-17	81.0
WP_107131778.1\|287890_288373_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	5.5e-55	71.9
WP_107131779.1\|288373_288628_-	hypothetical protein	A0A059T5G2	Listeria_phage	3.4e-40	92.8
WP_107131781.1\|288830_289028_-	hypothetical protein	A8ASP4	Listeria_phage	5.2e-20	71.9
WP_107131782.1\|289024_289234_-	hypothetical protein	A0A059T6C7	Listeria_phage	1.2e-14	62.1
WP_107131783.1\|289230_289446_-	hypothetical protein	NA	NA	NA	NA
WP_107131784.1\|289442_289727_-	hypothetical protein	A0A059T7S7	Listeria_phage	5.0e-40	86.2
WP_107131785.1\|289726_290230_-	hypothetical protein	A0A0B5CYR4	Listeria_phage	1.6e-28	45.4
WP_107131786.1\|290226_290790_-	DUF1642 domain-containing protein	A0A0B5D0I5	Listeria_phage	4.9e-55	77.7
WP_107131787.1\|290786_290996_-	hypothetical protein	A8ASN7	Listeria_phage	6.1e-27	92.8
WP_107131788.1\|291045_291966_-	hypothetical protein	A0A0B5D175	Listeria_phage	5.5e-19	37.0
WP_003725086.1\|291995_292811_-	recombinase RecT	A8ATY6	Listeria_phage	4.2e-148	97.4
WP_003740962.1\|292813_293773_-	YqaJ viral recombinase family protein	A8ATY5	Listeria_phage	1.3e-177	98.7
WP_003734954.1\|294005_294194_-	hypothetical protein	A0A0B5CU43	Listeria_phage	4.5e-29	100.0
WP_003731816.1\|294209_294395_-	helix-turn-helix domain-containing protein	A0A059T674	Listeria_phage	1.1e-27	100.0
WP_038330216.1\|294401_294926_-	hypothetical protein	A8ATY1	Listeria_phage	2.0e-87	97.7
WP_107131789.1\|295256_295448_-	hypothetical protein	A0A059T5E9	Listeria_phage	7.0e-30	100.0
WP_060595895.1\|295459_295654_-	hypothetical protein	A0A059T6E5	Listeria_phage	2.8e-26	98.4
WP_003733688.1\|295674_295884_-	helix-turn-helix domain-containing protein	A0A0B5D0D3	Listeria_phage	3.5e-30	95.6
WP_003724014.1\|296049_296472_+	helix-turn-helix transcriptional regulator	A0A0B5CYL9	Listeria_phage	7.7e-69	98.6
WP_003724015.1\|296487_296913_+	ImmA/IrrE family metallo-endopeptidase	A0A0B5CTZ7	Listeria_phage	2.2e-76	100.0
WP_003724016.1\|296927_297635_+	hypothetical protein	A0A0B5CTT6	Listeria_phage	2.8e-124	100.0
WP_061385618.1\|297693_298395_+	hypothetical protein	A0A0B5D125	Listeria_phage	6.7e-102	100.0
WP_107131790.1\|298409_298946_+	hypothetical protein	A0A0B5D0D1	Listeria_phage	6.9e-06	33.6
WP_107131791.1\|299040_300243_+\|integrase	site-specific integrase	A0A059T666	Listeria_phage	9.4e-221	99.2
WP_003734164.1\|300509_301466_-	NAD(P)-binding domain-containing protein	M1H502	Paramecium_bursaria_Chlorella_virus	1.6e-29	29.6
300348:300392	attR	NA	NA	NA	NA

DBSCAN-SWA_2

773940 : 781785

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722610.1\|773940_774900_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7
WP_003725411.1\|775019_776003_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.0e-52	38.1
WP_003741152.1\|776019_777081_+	galactose mutarotase	NA	NA	NA	NA
WP_003734494.1\|777122_778853_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	5.6e-174	53.3
WP_003722606.1\|778960_779836_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_003734495.1\|779837_780806_+	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-68	43.6
WP_003725407.1\|780813_781785_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4

DBSCAN-SWA_3

1506991 : 1515277

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726215.1\|1506991_1508284_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0
WP_003734637.1\|1508364_1509078_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	6.7e-41	38.3
WP_003722248.1\|1509089_1509335_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003734638.1\|1509338_1510022_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003731570.1\|1510014_1512234_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	6.5e-159	40.8
WP_003722245.1\|1512218_1513646_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_003726210.1\|1513664_1514714_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
WP_107131806.1\|1514710_1515277_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	8.3e-26	38.5

DBSCAN-SWA_4

2009574 : 2068173

Streptococcus_phage(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003734511.1\|2009574_2011281_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003734512.1\|2011321_2012584_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003726414.1\|2012597_2013740_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003734513.1\|2013754_2014543_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003727497.1\|2014556_2015315_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
WP_003723450.1\|2015545_2016103_-	ribosome recycling factor	NA	NA	NA	NA
WP_003723449.1\|2016102_2016831_-	UMP kinase	NA	NA	NA	NA
WP_003734514.1\|2017123_2017498_+	hypothetical protein	NA	NA	NA	NA
WP_003744007.1\|2017475_2018681_+	helicase SNF2	L0P6E9	Lactobacillus_phage	4.1e-91	46.6
WP_003727499.1\|2018670_2019975_+	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	1.2e-133	52.1
WP_003726669.1\|2019984_2020491_+	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	1.4e-56	66.7
WP_003726668.1\|2020512_2021244_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.3e-81	58.0
WP_003726667.1\|2021292_2021532_-	YneF family protein	NA	NA	NA	NA
WP_003734516.1\|2021752_2023747_-	transketolase	NA	NA	NA	NA
WP_003734517.1\|2023893_2024121_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003734518.1\|2024214_2024544_-	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003723438.1\|2024700_2025315_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003734519.1\|2025345_2025870_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003726564.1\|2025903_2027199_-	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.5e-147	62.6
WP_003723435.1\|2027342_2028677_-	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_003719570.1\|2028747_2029116_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003727505.1\|2029317_2030544_-	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_012681271.1\|2030536_2031760_-	GTPase HflX	NA	NA	NA	NA
WP_003719566.1\|2031870_2032104_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_003726658.1\|2032225_2033143_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003723738.1\|2033268_2034945_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_003726657.1\|2035177_2035876_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	6.4e-12	31.9
WP_003734520.1\|2036088_2037975_+	acetyltransferase	B5WZU0	Pseudomonas_phage	2.9e-43	32.2
WP_003734521.1\|2038007_2039828_-	class 1 internalin InlK	NA	NA	NA	NA
WP_003726814.1\|2040455_2040923_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_003734522.1\|2041005_2043465_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.6
WP_003727510.1\|2043461_2045429_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.1e-123	42.5
WP_003727511.1\|2045609_2046017_-	CoA-binding protein	NA	NA	NA	NA
WP_003726698.1\|2046175_2046772_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003726697.1\|2046813_2047686_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724130.1\|2047688_2048000_-	hypothetical protein	NA	NA	NA	NA
WP_003727513.1\|2048022_2048442_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003726695.1\|2048544_2049324_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_003727514.1\|2049344_2050754_-\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	7.5e-44	27.8
WP_003724001.1\|2050767_2051307_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003731303.1\|2051327_2052230_-	tyrosine recombinase XerC	A0A142K7N4	Mycobacterium_phage	1.8e-14	29.5
WP_003727516.1\|2052512_2053817_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003727517.1\|2053879_2055958_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	5.4e-107	37.5
WP_003727518.1\|2056230_2057091_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003727519.1\|2057224_2058010_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
WP_003726396.1\|2058006_2058870_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003727520.1\|2058879_2059422_-	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003726394.1\|2059523_2060093_-	type I signal peptidase SipY	NA	NA	NA	NA
WP_003726393.1\|2060127_2060694_-	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723886.1\|2060812_2062072_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723884.1\|2062256_2063540_-	trigger factor	NA	NA	NA	NA
WP_003727521.1\|2063654_2064593_-	hypothetical protein	NA	NA	NA	NA
WP_003731300.1\|2064854_2065520_-	hypothetical protein	NA	NA	NA	NA
WP_003727523.1\|2065535_2066069_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003727524.1\|2066192_2066408_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003723563.1\|2066558_2066954_+	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003734523.1\|2067033_2068173_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP028333

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection