CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020467	Staphylococcus aureus strain CFSAN007896 chromosome, complete genome	9 crisprs	csa3,cas3,DEDDh,DinG,WYL	4	0	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020467_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_1

858307-858386

Orphan

Consensus_repeat	Method
CCGTCAGCTTCTGTGTTGGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020467_1

>merge|NZ_CP020467|1|858307-858386|CRISPRCasFinder
CCGTCAGCTTCTGTGTTGGGGCCCACCCCAACTTGCATTGCTTGTAAGCTGACTTTCCGTCAGCTTCTATGTTGGGGCCC

>NZ_CP020467|1|1|858307-858386|CRISPRCasFinder
CCGTCAGCTTCTGTGTTGGGGCCC	ACCCCAACTTGCATTGCTTGTAAGCTGACTTT
CCGTCAGCTTCTATGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_000974455.1\|853580_854003_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP020467.1\|WP_001018965.1\|858643_859030_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP020467.1\|WP_001065804.1\|859022_859319_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP020467.1\|WP_000150036.1\|854150_854867_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP020467.1\|WP_000290491.1\|856616_856997_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP020467.1\|WP_001798062.1\|857174_858053_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP020467.1\|WP_000732338.1\|861299_862121_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP020467.1\|WP_000569884.1\|852687_853182_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP020467.1\|WP_000752917.1\|862935_863130_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP020467.1\|WP_000807671.1\|866823_868065_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP020467.1\|WP_001183862.1\|863363_864215_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP020467.1\|WP_000205572.1\|865401_866709_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP020467.1\|WP_000422908.1\|854949_855489_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP020467.1\|WP_000255545.1\|851914_852532_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP020467.1\|WP_000520233.1\|860586_861282_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP020467.1\|WP_001147955.1\|855638_855959_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP020467.1\|WP_016187137.1\|851281_851842_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP020467.1\|WP_000571209.1\|859568_860594_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP020467.1\|WP_107375202.1\|864542_865304_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP020467.1\|WP_000589549.1\|856102_856459_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_000974455.1\|853580_854003_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.40241e-61
NZ_CP020467.1\|WP_001018965.1\|858643_859030_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	1.24029e-35
NZ_CP020467.1\|WP_001065804.1\|859022_859319_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.8621e-13
NZ_CP020467.1\|WP_000150036.1\|854150_854867_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	6.29269e-147
NZ_CP020467.1\|WP_000290491.1\|856616_856997_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
NZ_CP020467.1\|WP_001798062.1\|857174_858053_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.81941e-75
NZ_CP020467.1\|WP_000732338.1\|861299_862121_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	5.3847e-113
NZ_CP020467.1\|WP_000569884.1\|852687_853182_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP020467.1\|WP_000752917.1\|862935_863130_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP020467.1\|WP_000807671.1\|866823_868065_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP020467.1\|WP_001183862.1\|863363_864215_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	1.10175e-76
NZ_CP020467.1\|WP_000205572.1\|865401_866709_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
NZ_CP020467.1\|WP_000422908.1\|854949_855489_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP020467.1\|WP_000255545.1\|851914_852532_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	5.25608e-61
NZ_CP020467.1\|WP_000520233.1\|860586_861282_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP020467.1\|WP_001147955.1\|855638_855959_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	3.63533e-24
NZ_CP020467.1\|WP_016187137.1\|851281_851842_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.24579e-44
NZ_CP020467.1\|WP_000571209.1\|859568_860594_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.26346e-169
NZ_CP020467.1\|WP_107375202.1\|864542_865304_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.28655e-150
NZ_CP020467.1\|WP_000589549.1\|856102_856459_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56

>NZ_CP020467.1|WP_001798062.1|857174_858053_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLKDIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDDLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP020467.1|WP_000290491.1|856616_856997_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>NZ_CP020467.1|WP_000589549.1|856102_856459_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP020467.1|WP_001147955.1|855638_855959_-|thioredoxin-family-protein
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP020467.1|WP_000422908.1|854949_855489_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP020467.1|WP_000150036.1|854150_854867_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATITPQLYIEETLIQKINHRIDAIDVLELRIDQFENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVIISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP020467.1|WP_000974455.1|853580_854003_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDPDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP020467.1|WP_000569884.1|852687_853182_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP020467.1|WP_000255545.1|851914_852532_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLFIIIAVVGVSIIIMSLPILQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_CP020467.1|WP_016187137.1|851281_851842_+|histidine-phosphatase-family-protein
MRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEDRIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_CP020467.1|WP_001018965.1|858643_859030_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSNDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPFLPNINNERLVLVNE
>NZ_CP020467.1|WP_001065804.1|859022_859319_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIYGYTPTCGTCKVSERMLDITNEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFQSVTDLLENLK
>NZ_CP020467.1|WP_000571209.1|859568_860594_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIILITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHAVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSIDFGKFEKELIERQVKMEVLRHG
>NZ_CP020467.1|WP_000520233.1|860586_861282_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP020467.1|WP_000732338.1|861299_862121_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGSKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGNVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP020467.1|WP_000752917.1|862935_863130_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP020467.1|WP_001183862.1|863363_864215_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNSDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP020467.1|WP_107375202.1|864542_865304_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTYEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP020467.1|WP_000205572.1|865401_866709_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP020467.1|WP_000807671.1|866823_868065_+|cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

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Crispr_ID: NZ_CP020467_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_2

907427-907512

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020467_2

>merge|NZ_CP020467|2|907427-907512|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGTGGAAAGCCAGCTTACAATAATGTGCAAGTTGG

>NZ_CP020467|2|2|907427-907512|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGTGG
AAAGCCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_000838047.1\|903297_904425_+\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_CP020467.1\|WP_000670753.1\|922574_923477_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP020467.1\|WP_000054599.1\|898567_900973_-\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
NZ_CP020467.1\|WP_000154949.1\|918755_922409_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP020467.1\|WP_001081626.1\|898146_898575_-\|Na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
NZ_CP020467.1\|WP_011443624.1\|897805_898135_-\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
NZ_CP020467.1\|WP_000148855.1\|911766_913098_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CP020467.1\|WP_000035058.1\|901550_902144_+\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
NZ_CP020467.1\|WP_000781162.1\|901103_901487_-\|kinase	unknown	unknown	gnl\|CDD\|378054
NZ_CP020467.1\|WP_000660054.1\|910210_911416_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_CP020467.1\|WP_000007960.1\|913423_913999_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP020467.1\|WP_000172367.1\|915278_918755_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP020467.1\|WP_000066056.1\|908841_910221_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CP020467.1\|WP_000573088.1\|896316_897813_-\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
NZ_CP020467.1\|WP_000758217.1\|914003_914528_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP020467.1\|WP_000185311.1\|907670_908600_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_CP020467.1\|WP_000711897.1\|914543_915119_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP020467.1\|WP_000138487.1\|906031_907276_+\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_CP020467.1\|WP_000167321.1\|904732_905923_+\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_CP020467.1\|WP_001067294.1\|902558_902936_+\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_000838047.1\|903297_904425_+\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_CP020467.1\|WP_000670753.1\|922574_923477_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.54658e-87
NZ_CP020467.1\|WP_000054599.1\|898567_900973_-\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP020467.1\|WP_000154949.1\|918755_922409_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP020467.1\|WP_001081626.1\|898146_898575_-\|Na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
NZ_CP020467.1\|WP_011443624.1\|897805_898135_-\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
NZ_CP020467.1\|WP_000148855.1\|911766_913098_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP020467.1\|WP_000035058.1\|901550_902144_+\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
NZ_CP020467.1\|WP_000781162.1\|901103_901487_-\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
NZ_CP020467.1\|WP_000660054.1\|910210_911416_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CP020467.1\|WP_000007960.1\|913423_913999_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	4.0006e-40
NZ_CP020467.1\|WP_000172367.1\|915278_918755_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP020467.1\|WP_000066056.1\|908841_910221_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP020467.1\|WP_000573088.1\|896316_897813_-\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP020467.1\|WP_000758217.1\|914003_914528_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.75286e-49
NZ_CP020467.1\|WP_000185311.1\|907670_908600_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	8.83368e-151
NZ_CP020467.1\|WP_000711897.1\|914543_915119_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
NZ_CP020467.1\|WP_000138487.1\|906031_907276_+\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP020467.1\|WP_000167321.1\|904732_905923_+\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP020467.1\|WP_001067294.1\|902558_902936_+\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44

>NZ_CP020467.1|WP_000138487.1|906031_907276_+|Glu/Leu/Phe/Val-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_CP020467.1|WP_000167321.1|904732_905923_+|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINKNTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFARDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_CP020467.1|WP_000838047.1|903297_904425_+|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVVLPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITSNAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPIAVIEEVLKSKEVYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATAREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADDALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_CP020467.1|WP_001067294.1|902558_902936_+|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_CP020467.1|WP_000035058.1|901550_902144_+|peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>NZ_CP020467.1|WP_000781162.1|901103_901487_-|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>NZ_CP020467.1|WP_000054599.1|898567_900973_-|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASKANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>NZ_CP020467.1|WP_001081626.1|898146_898575_-|Na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>NZ_CP020467.1|WP_011443624.1|897805_898135_-|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>NZ_CP020467.1|WP_000573088.1|896316_897813_-|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPLRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAITRTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>NZ_CP020467.1|WP_000185311.1|907670_908600_-|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNHIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDENVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNKNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_CP020467.1|WP_000066056.1|908841_910221_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLSTYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_CP020467.1|WP_000660054.1|910210_911416_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMRAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>NZ_CP020467.1|WP_000148855.1|911766_913098_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_CP020467.1|WP_000007960.1|913423_913999_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVDTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>NZ_CP020467.1|WP_000758217.1|914003_914528_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKKLDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>NZ_CP020467.1|WP_000711897.1|914543_915119_+|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>NZ_CP020467.1|WP_000172367.1|915278_918755_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEISNELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQINPMLRLLKTDVLTTSYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLSQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_CP020467.1|WP_000154949.1|918755_922409_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYETGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDISYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFHEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTLDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVRYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVFDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIIYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADTKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP020467.1|WP_000670753.1|922574_923477_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNAKIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: NZ_CP020467_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_3

1208784-1208876

Unclear

Consensus_repeat	Method
TAAGAAACAGTAATCAATAAATTGATAACT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP020467_3

>merge|NZ_CP020467|3|1208784-1208876|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACTAATAAGCGGAACGCCTGAGCTAAAGCTCATGCATAAGAAACAGTAATCAATAAATTGATAACT

>NZ_CP020467|3|3|1208784-1208876|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACT	AATAAGCGGAACGCCTGAGCTAAAGCTCATGCA
TAAGAAACAGTAATCAATAAATTGATAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_000262717.1\|1210192_1213759_+\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NZ_CP020467.1\|WP_000171418.1\|1200962_1201337_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP020467.1\|WP_000547905.1\|1199309_1199951_+\|thiamine-diphosphokinase	unknown	unknown	gnl\|CDD\|224480
NZ_CP020467.1\|WP_000623906.1\|1201351_1202998_+\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|224378
NZ_CP020467.1\|WP_000007675.1\|1213758_1215009_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP020467.1\|WP_107375210.1\|1215353_1216721_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP020467.1\|WP_000043237.1\|1209314_1210046_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_CP020467.1\|WP_000181404.1\|1218961_1219312_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP020467.1\|WP_000268754.1\|1217155_1217431_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NZ_CP020467.1\|WP_001261987.1\|1217618_1218122_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP020467.1\|WP_001548538.1\|1205450_1206023_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_CP020467.1\|WP_000531319.1\|1214995_1215328_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP020467.1\|WP_107375208.1\|1206027_1207014_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_CP020467.1\|WP_000687323.1\|1218121_1218859_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP020467.1\|WP_000164332.1\|1198658_1199303_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_CP020467.1\|WP_000426914.1\|1208965_1209199_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP020467.1\|WP_000167269.1\|1207925_1208660_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP020467.1\|WP_000517908.1\|1200331_1200520_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP020467.1\|WP_107375209.1\|1207006_1207933_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP020467.1\|WP_001151515.1\|1203187_1205248_+\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_000262717.1\|1210192_1213759_+\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NZ_CP020467.1\|WP_000171418.1\|1200962_1201337_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
NZ_CP020467.1\|WP_000547905.1\|1199309_1199951_+\|thiamine-diphosphokinase	gnl\|CDD\|224480	COG1564, THI80, Thiamine pyrophosphokinase [Coenzyme metabolism].	1.16343e-81
NZ_CP020467.1\|WP_000623906.1\|1201351_1202998_+\|DAK2-domain-containing-protein	gnl\|CDD\|224378	COG1461, COG1461, Predicted kinase related to dihydroxyacetone kinase [General function prediction only].	0
NZ_CP020467.1\|WP_000007675.1\|1213758_1215009_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NZ_CP020467.1\|WP_107375210.1\|1215353_1216721_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP020467.1\|WP_000043237.1\|1209314_1210046_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NZ_CP020467.1\|WP_000181404.1\|1218961_1219312_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NZ_CP020467.1\|WP_000268754.1\|1217155_1217431_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NZ_CP020467.1\|WP_001261987.1\|1217618_1218122_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02289e-68
NZ_CP020467.1\|WP_001548538.1\|1205450_1206023_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
NZ_CP020467.1\|WP_000531319.1\|1214995_1215328_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	1.00966e-46
NZ_CP020467.1\|WP_107375208.1\|1206027_1207014_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	1.23106e-175
NZ_CP020467.1\|WP_000687323.1\|1218121_1218859_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	3.27017e-164
NZ_CP020467.1\|WP_000164332.1\|1198658_1199303_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	1.52718e-114
NZ_CP020467.1\|WP_000426914.1\|1208965_1209199_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_CP020467.1\|WP_000167269.1\|1207925_1208660_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
NZ_CP020467.1\|WP_000517908.1\|1200331_1200520_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NZ_CP020467.1\|WP_107375209.1\|1207006_1207933_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	7.86207e-134
NZ_CP020467.1\|WP_001151515.1\|1203187_1205248_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0

>NZ_CP020467.1|WP_000167269.1|1207925_1208660_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NZ_CP020467.1|WP_107375209.1|1207006_1207933_+|ACP-S-malonyltransferase
MSKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNLNPDFTIGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPSGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>NZ_CP020467.1|WP_107375208.1|1206027_1207014_+|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTGVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKIAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>NZ_CP020467.1|WP_001548538.1|1205450_1206023_+|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>NZ_CP020467.1|WP_001151515.1|1203187_1205248_+|ATP-dependent-DNA-helicase-RecG
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFLNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLIALFGDSMNVALLTGSVKGKKRKILLEQLENRTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>NZ_CP020467.1|WP_000623906.1|1201351_1202998_+|DAK2-domain-containing-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKLDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLADDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
>NZ_CP020467.1|WP_000171418.1|1200962_1201337_+|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>NZ_CP020467.1|WP_000517908.1|1200331_1200520_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NZ_CP020467.1|WP_000547905.1|1199309_1199951_+|thiamine-diphosphokinase
MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFFSVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGRLDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTDDVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN
>NZ_CP020467.1|WP_000164332.1|1198658_1199303_+|ribulose-phosphate-3-epimerase
MTKLYPSLLSVDFLDLQHELKRLEEAGVDGVHFDVMDGQFVPNISIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQMIKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNAIKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG
>NZ_CP020467.1|WP_000426914.1|1208965_1209199_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NZ_CP020467.1|WP_000043237.1|1209314_1210046_+|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NZ_CP020467.1|WP_000262717.1|1210192_1213759_+|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVNDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLVERKKNQSETNARYEEEQENLIELLENISSEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEVKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRAVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESLTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLNDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEATLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAMFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NZ_CP020467.1|WP_000007675.1|1213758_1215009_+|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENDEVKSLTEEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLISRYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGAK
>NZ_CP020467.1|WP_000531319.1|1214995_1215328_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKKHLSNPEQIQRYIQQLEDLE
>NZ_CP020467.1|WP_107375210.1|1215353_1216721_+|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAANVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NZ_CP020467.1|WP_000268754.1|1217155_1217431_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NZ_CP020467.1|WP_001261987.1|1217618_1218122_+|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>NZ_CP020467.1|WP_000687323.1|1218121_1218859_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQARVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NZ_CP020467.1|WP_000181404.1|1218961_1219312_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

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Crispr_ID: NZ_CP020467_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_4

1974519-1974643

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020467_4

>merge|NZ_CP020467|4|1974519-1974643|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>NZ_CP020467|4|4|1974519-1974643|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_107375271.1\|1986314_1987409_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP020467.1\|WP_000031108.1\|1967675_1967828_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000181394.1\|1968610_1969081_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297
NZ_CP020467.1\|WP_000110011.1\|1982697_1983144_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NZ_CP020467.1\|WP_000869463.1\|1983240_1984191_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NZ_CP020467.1\|WP_000669380.1\|1963821_1964643_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP020467.1\|WP_000597238.1\|1987599_1989336_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	unknown	unknown	gnl\|CDD\|224055
NZ_CP020467.1\|WP_001251219.1\|1967852_1968452_-\|glucosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|223440
NZ_CP020467.1\|WP_001793998.1\|1969085_1970228_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl\|CDD\|272993
NZ_CP020467.1\|WP_000901019.1\|1966679_1967075_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_001144055.1\|1970363_1971092_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP020467.1\|WP_000437967.1\|1962546_1963659_-\|GAF-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP020467.1\|WP_000379091.1\|1991659_1992637_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NZ_CP020467.1\|WP_000284755.1\|1990470_1991508_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_CP020467.1\|WP_000886472.1\|1992897_1993734_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224596
NZ_CP020467.1\|WP_000116227.1\|1965098_1966484_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP020467.1\|WP_000939530.1\|1984196_1984652_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|224146
NZ_CP020467.1\|WP_000251252.1\|1989625_1990168_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_CP020467.1\|WP_001011603.1\|1984732_1986022_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493
NZ_CP020467.1\|WP_000063551.1\|1972793_1973855_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_000251252.1\|1989625_1990168_-\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.0244e-125
NZ_CP020467.1\|WP_107375271.1\|1986314_1987409_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.68187e-86
NZ_CP020467.1\|WP_000181394.1\|1968610_1969081_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
NZ_CP020467.1\|WP_000110011.1\|1982697_1983144_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
NZ_CP020467.1\|WP_000869463.1\|1983240_1984191_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	8.45391e-136
NZ_CP020467.1\|WP_001011603.1\|1984732_1986022_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
NZ_CP020467.1\|WP_000597238.1\|1987599_1989336_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP020467.1\|WP_001251219.1\|1967852_1968452_-\|glucosamine-6-phosphate-isomerase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
NZ_CP020467.1\|WP_001793998.1\|1969085_1970228_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	1.304e-179
NZ_CP020467.1\|WP_000669380.1\|1963821_1964643_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.57209e-78
NZ_CP020467.1\|WP_001144055.1\|1970363_1971092_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.22702e-152
NZ_CP020467.1\|WP_000437967.1\|1962546_1963659_-\|GAF-domain-containing-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.94275e-57
NZ_CP020467.1\|WP_000379091.1\|1991659_1992637_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.21408e-39
NZ_CP020467.1\|WP_000284755.1\|1990470_1991508_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	4.67816e-157
NZ_CP020467.1\|WP_000886472.1\|1992897_1993734_-\|hypothetical-protein	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	0.000164936
NZ_CP020467.1\|WP_000116227.1\|1965098_1966484_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP020467.1\|WP_000063551.1\|1972793_1973855_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.65132e-122
NZ_CP020467.1\|WP_000939530.1\|1984196_1984652_-\|peroxiredoxin	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.5916e-68

>NZ_CP020467.1|WP_000063551.1|1972793_1973855_-|PTS-transporter-subunit-IIC
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>NZ_CP020467.1|WP_001144055.1|1970363_1971092_-|amino-acid-ABC-transporter-ATP-binding-protein
MPVIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>NZ_CP020467.1|WP_001793998.1|1969085_1970228_-|tRNA-epoxyqueuosine(34)-reductase-QueG
MGGIRLDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>NZ_CP020467.1|WP_000181394.1|1968610_1969081_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>NZ_CP020467.1|WP_001251219.1|1967852_1968452_-|glucosamine-6-phosphate-isomerase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>NZ_CP020467.1|WP_000031108.1|1967675_1967828_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>NZ_CP020467.1|WP_000901019.1|1966679_1967075_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPIIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>NZ_CP020467.1|WP_000116227.1|1965098_1966484_-|class-II-fumarate-hydratase
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHHSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAQYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>NZ_CP020467.1|WP_000669380.1|1963821_1964643_+|RluA-family-pseudouridine-synthase
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTVDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>NZ_CP020467.1|WP_000437967.1|1962546_1963659_-|GAF-domain-containing-sensor-histidine-kinase
MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK
>NZ_CP020467.1|WP_000110011.1|1982697_1983144_-|peroxide-responsive-transcriptional-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>NZ_CP020467.1|WP_000869463.1|1983240_1984191_-|2-hydroxyacid-dehydrogenase
MKVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLANLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>NZ_CP020467.1|WP_000939530.1|1984196_1984652_-|peroxiredoxin
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIVYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKYGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>NZ_CP020467.1|WP_001011603.1|1984732_1986022_+|glutamate-1-semialdehyde-2,1-aminomutase
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHSNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
>NZ_CP020467.1|WP_107375271.1|1986314_1987409_+|aromatic-acid-exporter-family-protein
MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPVTKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>NZ_CP020467.1|WP_000597238.1|1987599_1989336_-|SAV1866-family-putative-multidrug-efflux-ABC-transporter
MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
>NZ_CP020467.1|WP_000251252.1|1989625_1990168_-|DUF402-domain-containing-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKDRYKKIRQY
>NZ_CP020467.1|WP_000284755.1|1990470_1991508_-|A/G-specific-adenine-glycosylase
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFKSEHARREMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGTINIERLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>NZ_CP020467.1|WP_000379091.1|1991659_1992637_+|metal-dependent-hydrolase
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTHPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVVGLHPLAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQKLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTKDNVIDHSYIGWVFTEDKLQRKLYAK
>NZ_CP020467.1|WP_000886472.1|1992897_1993734_-|hypothetical-protein
MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRLIALIVFAVLMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGICVLCFLVLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSKDSTDEADTSS

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Crispr_ID: NZ_CP020467_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_5

2019464-2019655

Orphan

Consensus_repeat	Method
NNTCTNTGTTGGGGCCCNCACC	CRT

3 spacers

DEDDh

The CRISPR arrays of NZ_CP020467_5

>merge|NZ_CP020467|5|2019464-2019655|CRT
CTCTATGTTTGGGGCCCCACCCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCCTTTCGAAATTCTCTTTGTTGGGGCCCCACCCTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTTTGTTGGGGCCCCACT

>NZ_CP020467|5|1|2019464-2019655|CRT
CTCTATGTTTGGGGCCCCACC	CCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAG
CTTCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAATTTCCTTTCGAAAT
TCTCTTTGTTGGGGCCCCACC	CTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAG
CTTCTTTGTTGGGGCCCCACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_001250339.1\|2011798_2013112_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP020467.1\|WP_107375238.1\|2028558_2030751_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_CP020467.1\|WP_001147874.1\|2016932_2018294_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_CP020467.1\|WP_000272063.1\|2030747_2031440_-\|heptaprenylglyceryl-phosphate-synthase	unknown	unknown	gnl\|CDD\|224560
NZ_CP020467.1\|WP_001231458.1\|2018374_2019322_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
NZ_CP020467.1\|WP_001790257.1\|2010869_2010980_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000170162.1\|2023043_2023346_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|178810
NZ_CP020467.1\|WP_000545373.1\|2020144_2021572_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489
NZ_CP020467.1\|WP_000957023.1\|2023712_2025251_+\|sodium/proline-symporter-PutP	unknown	unknown	gnl\|CDD\|273981
NZ_CP020467.1\|WP_001790679.1\|2013985_2014078_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000140179.1\|2014915_2015986_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP020467.1\|WP_000548777.1\|2016232_2016763_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP020467.1\|WP_000027924.1\|2021584_2023042_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl\|CDD\|234572
NZ_CP020467.1\|WP_000774552.1\|2026551_2028555_-\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_CP020467.1\|WP_000831695.1\|2025339_2026539_-\|CamS-family-sex-pheromone-protein	unknown	unknown	gnl\|CDD\|227188
NZ_CP020467.1\|WP_000544973.1\|2011065_2011797_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP020467.1\|WP_001165363.1\|2031611_2031914_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226893
NZ_CP020467.1\|WP_000613738.1\|2014294_2014849_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP020467.1\|WP_001791535.1\|2019959_2020106_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000949466.1\|2013403_2013904_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_001250339.1\|2011798_2013112_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.60835e-98
NZ_CP020467.1\|WP_107375238.1\|2028558_2030751_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP020467.1\|WP_001147874.1\|2016932_2018294_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
NZ_CP020467.1\|WP_001231458.1\|2018374_2019322_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
NZ_CP020467.1\|WP_000545373.1\|2020144_2021572_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_CP020467.1\|WP_000831695.1\|2025339_2026539_-\|CamS-family-sex-pheromone-protein	gnl\|CDD\|227188	COG4851, CamS, Protein involved in sex pheromone biosynthesis [General function prediction only].	0
NZ_CP020467.1\|WP_000272063.1\|2030747_2031440_-\|heptaprenylglyceryl-phosphate-synthase	gnl\|CDD\|224560	COG1646, COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold [General function prediction only].	2.53994e-99
NZ_CP020467.1\|WP_000957023.1\|2023712_2025251_+\|sodium/proline-symporter-PutP	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP020467.1\|WP_000140179.1\|2014915_2015986_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP020467.1\|WP_000548777.1\|2016232_2016763_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.54005e-11
NZ_CP020467.1\|WP_000027924.1\|2021584_2023042_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_CP020467.1\|WP_000774552.1\|2026551_2028555_-\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP020467.1\|WP_000544973.1\|2011065_2011797_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
NZ_CP020467.1\|WP_001165363.1\|2031611_2031914_-\|hypothetical-protein	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	1.66593e-59
NZ_CP020467.1\|WP_000613738.1\|2014294_2014849_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NZ_CP020467.1\|WP_000170162.1\|2023043_2023346_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	5.296e-34
NZ_CP020467.1\|WP_000949466.1\|2013403_2013904_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	1.15329e-74

>NZ_CP020467.1|WP_001231458.1|2018374_2019322_-|diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
>NZ_CP020467.1|WP_001147874.1|2016932_2018294_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMGSCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMVIFVTNGKNWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPSTQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>NZ_CP020467.1|WP_000548777.1|2016232_2016763_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSAGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>NZ_CP020467.1|WP_000140179.1|2014915_2015986_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYRNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSTRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP020467.1|WP_000613738.1|2014294_2014849_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP020467.1|WP_001790679.1|2013985_2014078_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP020467.1|WP_000949466.1|2013403_2013904_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEEAMFETHINYLTRIGDDSNALYLYEKELGTRTFDEE
>NZ_CP020467.1|WP_001250339.1|2011798_2013112_-|Mur-ligase-family-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNGDDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISRFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP020467.1|WP_000544973.1|2011065_2011797_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>NZ_CP020467.1|WP_001790257.1|2010869_2010980_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP020467.1|WP_001791535.1|2019959_2020106_-|hypothetical-protein
MVADLDAIEGLFISIEVILLLTLFIVHVNGKNINFINALALIILRQTV
>NZ_CP020467.1|WP_000545373.1|2020144_2021572_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLSGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
>NZ_CP020467.1|WP_000027924.1|2021584_2023042_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADANDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
>NZ_CP020467.1|WP_000170162.1|2023043_2023346_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
>NZ_CP020467.1|WP_000957023.1|2023712_2025251_+|sodium/proline-symporter-PutP
MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLVRGEEKAKTHQKEFVMVGRLSVLAVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDIVREK
>NZ_CP020467.1|WP_000831695.1|2025339_2026539_-|CamS-family-sex-pheromone-protein
MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIATDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQDGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETDPEKIAEKSPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVKKQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNEWHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRLVVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEPQVHIYSN
>NZ_CP020467.1|WP_000774552.1|2026551_2028555_-|NAD-dependent-DNA-ligase-LigA
MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEFKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVSDIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
>NZ_CP020467.1|WP_107375238.1|2028558_2030751_-|DNA-helicase-PcrA
MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSSYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
>NZ_CP020467.1|WP_000272063.1|2030747_2031440_-|heptaprenylglyceryl-phosphate-synthase
MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHLYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
>NZ_CP020467.1|WP_001165363.1|2031611_2031914_-|hypothetical-protein
MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLSQRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP020467_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_6

2127744-2127832

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020467_6

>merge|NZ_CP020467|6|2127744-2127832|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>NZ_CP020467|6|5|2127744-2127832|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_001103930.1\|2126142_2126460_-\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_CP020467.1\|WP_000197638.1\|2131978_2132722_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP020467.1\|WP_000356937.1\|2122808_2123189_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_107375244.1\|2129827_2131444_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP020467.1\|WP_000522388.1\|2134196_2134823_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP020467.1\|WP_000447451.1\|2123500_2125210_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP020467.1\|WP_001190608.1\|2121293_2121635_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_001549197.1\|2136570_2136705_-\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP020467.1\|WP_001019766.1\|2122170_2122812_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374630
NZ_CP020467.1\|WP_000867948.1\|2135183_2135969_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP020467.1\|WP_000153640.1\|2127507_2127726_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP020467.1\|WP_000403839.1\|2126460_2126844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000620857.1\|2127898_2128573_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP020467.1\|WP_000179345.1\|2128586_2129759_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP020467.1\|WP_000481967.1\|2127185_2127503_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP020467.1\|WP_061641392.1\|2132746_2134000_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
NZ_CP020467.1\|WP_000708433.1\|2127033_2127189_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_001105709.1\|2136940_2137504_+\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_CP020467.1\|WP_001231378.1\|2126845_2127049_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000917289.1\|2131519_2131804_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_001103930.1\|2126142_2126460_-\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	2.13556e-19
NZ_CP020467.1\|WP_000179345.1\|2128586_2129759_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.10093e-47
NZ_CP020467.1\|WP_107375244.1\|2129827_2131444_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP020467.1\|WP_000522388.1\|2134196_2134823_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	7.96692e-115
NZ_CP020467.1\|WP_000447451.1\|2123500_2125210_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	4.69521e-166
NZ_CP020467.1\|WP_001019766.1\|2122170_2122812_-\|hypothetical-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	2.52046e-113
NZ_CP020467.1\|WP_000197638.1\|2131978_2132722_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.80796e-11
NZ_CP020467.1\|WP_000867948.1\|2135183_2135969_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.32273e-126
NZ_CP020467.1\|WP_061641392.1\|2132746_2134000_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	3.32976e-12
NZ_CP020467.1\|WP_000620857.1\|2127898_2128573_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NZ_CP020467.1\|WP_000153640.1\|2127507_2127726_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NZ_CP020467.1\|WP_000481967.1\|2127185_2127503_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_CP020467.1\|WP_001105709.1\|2136940_2137504_+\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	1.06502e-53
NZ_CP020467.1\|WP_001549197.1\|2136570_2136705_-\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NZ_CP020467.1\|WP_000917289.1\|2131519_2131804_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45

>NZ_CP020467.1|WP_000153640.1|2127507_2127726_-|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_CP020467.1|WP_000481967.1|2127185_2127503_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_CP020467.1|WP_000708433.1|2127033_2127189_-|hypothetical-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGEITTCENK
>NZ_CP020467.1|WP_001231378.1|2126845_2127049_-|hypothetical-protein
MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEQYFPDVSKDVQVVCLEMDLSKITEIKNKKKVGS
>NZ_CP020467.1|WP_000403839.1|2126460_2126844_-|hypothetical-protein
MEIKQKYQLSKVVKILEVVLYEEDKFQSDKDYHYQDKALYEYALKLVHNGLFNILAELDFEDEAFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGHVIGMLEWALDYIAGNIEVEEL
>NZ_CP020467.1|WP_001103930.1|2126142_2126460_-|DUF1474-family-protein
MNWEIKDLMCDIEAVKEKINDVAIKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKFHEIEKASSENFGEVSDDAQKLKITE
>NZ_CP020467.1|WP_000447451.1|2123500_2125210_-|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGIALNQLIPSKKEGEPDKKVFITSTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINASKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDIKAIYKRDYLCILGQTVHDKLGHEMQTITGQWGKKGYLIKGEKDRLQKKVSHKNIKYRGFAINKEMLEELGFDFSNSHNPYSDY
>NZ_CP020467.1|WP_000356937.1|2122808_2123189_-|hypothetical-protein
MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEMNHDYIGRTSVTHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>NZ_CP020467.1|WP_001019766.1|2122170_2122812_-|hypothetical-protein
MNIETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMAYVMMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLRLVTEFVQDENATQEDYKALEHKLTELKSSYYSLNK
>NZ_CP020467.1|WP_001190608.1|2121293_2121635_-|hypothetical-protein
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIIMTEQEKQQAMRSIKKLADGSMKRYEALKRIKV
>NZ_CP020467.1|WP_000620857.1|2127898_2128573_+|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NZ_CP020467.1|WP_000179345.1|2128586_2129759_+|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKTDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_CP020467.1|WP_107375244.1|2129827_2131444_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDATIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEVGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMSGMM
>NZ_CP020467.1|WP_000917289.1|2131519_2131804_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP020467.1|WP_000197638.1|2131978_2132722_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVYTQIFGTQQTSPNTERLIVIARKIPLFIFFVSIVGPLLEEYVFRKVIFGELFNAIKGNRIVAFAIATTVSSLIFALAHNDYKFIPIYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP020467.1|WP_061641392.1|2132746_2134000_-|hypothetical-protein
MSYHWFKKMLLSTSMLILSSSSSLGLATHTVEAKDNLNGEKPTTNLNHNVTSPSVNSEMNNNETGTPHESNQAGNEGTGSNSRDANPDSNNVKPDSNNQNPSPDSKPDPNNPNPGPNPKPDPDKPKPNPEPKPDPDKPKPNPEPKPDPDKPKPNPDPKPDPDKPKPNPDPKPDPNPNPNPKPDPNKPNPNPSPNPNQPGDSNQSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINQLGKEYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP020467.1|WP_000522388.1|2134196_2134823_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYENQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_CP020467.1|WP_000867948.1|2135183_2135969_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGKLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP020467.1|WP_001549197.1|2136570_2136705_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NZ_CP020467.1|WP_001105709.1|2136940_2137504_+|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTLAYILNIFIFTLITNISFYLIRRYAHGAHAPSSFWCYIESITLFIVLPLLVLHFHINETLMMFLALLSVGVVIKYAPAATKKKPIPARLVKQKRYFSIIISTILFIITLFVKEPYTQFIQLGIIIQAITLLPIYYSKED

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Crispr_ID: NZ_CP020467_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_7

2277570-2277771

Orphan

Consensus_repeat	Method
TCCTTGGTTGGCAGGTGCAGCTGGATGTGCTGTA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP020467_7

>merge|NZ_CP020467|7|2277570-2277771|PILER-CR
TGCTTGGTTGGCAGGTGCTGCTTGATTTCCAGGTTGTGCTTGTGCAGCGTTATTCGGATCAGCTTGATTACCTTGTCCAGCTGGTTGTGCTGTACCTGCTGCCGGTTGTGCTGCGCCTCCTGCTGGATTAGCCTGTCCACCTTGGTTTGCTGGTTGTGCTGCTGGTTGTCCTTGGTTGGCAGGTGCAGCTGGCTGTGCTGTA

>NZ_CP020467|7|1|2277570-2277771|PILER-CR
TGCTTGGTTGGCAGGTGCTGCTTGATTTCCAGGT	TGTGCTTGTGCAGCGTTATTCGGATCAGCTTGATTACCTTGTCCAGCT
GGTTGTGCTGTACCTGCTGCCGGTTGTGCTGCGC	CTCCTGCTGGATTAGCCTGTCCACCTTGGTTTGCTGGTTGTGCTGCTGGTTGTCCTTGGTTGGCAGGTGCAGCT
GGCTGTGCTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_000927367.1\|2266584_2268717_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP020467.1\|WP_001292150.1\|2268728_2269163_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP020467.1\|WP_000884730.1\|2294362_2295550_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_CP020467.1\|WP_001792784.1\|2259769_2259928_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000958522.1\|2288700_2289765_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP020467.1\|WP_001237527.1\|2292139_2293483_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP020467.1\|WP_000047120.1\|2293660_2294344_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP020467.1\|WP_073392962.1\|2258985_2259090_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000083795.1\|2265011_2266550_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP020467.1\|WP_000347896.1\|2280575_2281385_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP020467.1\|WP_000147093.1\|2295593_2296109_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|377294
NZ_CP020467.1\|WP_000648736.1\|2269162_2270269_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP020467.1\|WP_072435031.1\|2291544_2292018_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP020467.1\|WP_000162591.1\|2281574_2282483_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_CP020467.1\|WP_000334466.1\|2262525_2264331_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP020467.1\|WP_000894028.1\|2279641_2280574_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP020467.1\|WP_000277709.1\|2256913_2258560_+\|IS1182-like-element-ISSau3-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_CP020467.1\|WP_000370937.1\|2260586_2261444_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP020467.1\|WP_000521495.1\|2278259_2279615_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP020467.1\|WP_000908186.1\|2261511_2262294_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_000927367.1\|2266584_2268717_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.39374e-67
NZ_CP020467.1\|WP_001292150.1\|2268728_2269163_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	6.01856e-62
NZ_CP020467.1\|WP_000884730.1\|2294362_2295550_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	9.19785e-146
NZ_CP020467.1\|WP_000277709.1\|2256913_2258560_+\|IS1182-like-element-ISSau3-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.2166e-37
NZ_CP020467.1\|WP_000958522.1\|2288700_2289765_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	5.47694e-116
NZ_CP020467.1\|WP_001237527.1\|2292139_2293483_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.31901e-37
NZ_CP020467.1\|WP_000047120.1\|2293660_2294344_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	4.64044e-66
NZ_CP020467.1\|WP_072435031.1\|2291544_2292018_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	1.1244e-29
NZ_CP020467.1\|WP_000083795.1\|2265011_2266550_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP020467.1\|WP_000347896.1\|2280575_2281385_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP020467.1\|WP_000147093.1\|2295593_2296109_-\|metal-dependent-hydrolase	gnl\|CDD\|377294	pfam04307, YdjM, LexA-binding, inner membrane-associated putative hydrolase. YdjM is a family of putative LexA-binding proteins. Members are predicted to be membrane-bound metal-dependent hydrolases that may be acting as phospholipases. It is a member of the SOS network, that rescues cells from UV and other DNA-damage. Expression of YdjM is regulated by LexA.	4.64903e-24
NZ_CP020467.1\|WP_000648736.1\|2269162_2270269_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP020467.1\|WP_000162591.1\|2281574_2282483_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	5.94976e-145
NZ_CP020467.1\|WP_000334466.1\|2262525_2264331_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP020467.1\|WP_000894028.1\|2279641_2280574_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	4.21538e-117
NZ_CP020467.1\|WP_000521495.1\|2278259_2279615_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP020467.1\|WP_000370937.1\|2260586_2261444_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.15818e-59
NZ_CP020467.1\|WP_000908186.1\|2261511_2262294_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.75723e-107

>NZ_CP020467.1|WP_000648736.1|2269162_2270269_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALATGHQYDVILADESKTTTRVNNVAAINSMQPSEELKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLAYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP020467.1|WP_001292150.1|2268728_2269163_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEGNVDRIVQAKSAEEIKQVFEEADA
>NZ_CP020467.1|WP_000927367.1|2266584_2268717_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRITGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNLAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETRDKSSNMIDKDDVHIETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLISDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP020467.1|WP_000083795.1|2265011_2266550_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLATLVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP020467.1|WP_000334466.1|2262525_2264331_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP020467.1|WP_000908186.1|2261511_2262294_-|ABC-transporter-ATP-binding-protein
MLIQLDQVGRMKQGKTILKNISWQINEGDKWILYGLNGAGKTTLLNILNAYEPATTGYVNLFGKMPGKVGYSTETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP020467.1|WP_000370937.1|2260586_2261444_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPEDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQKETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP020467.1|WP_001792784.1|2259769_2259928_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP020467.1|WP_073392962.1|2258985_2259090_-|hypothetical-protein
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK
>NZ_CP020467.1|WP_000277709.1|2256913_2258560_+|IS1182-like-element-ISSau3-family-transposase
MYKNYNMTQLTLPIETSVRIPQNDISRYVNEIVETIPDSEFDEFRHHRGATSYHPKMMLKIILYAYTQSVFSGRRIEKLLHDSIRLMWLAQNQTPSYKTINRFRVNPNTDALIESLFIQFHSQCLKQNLIDDNSIFIDGTKVEANANRYTFVWKKSIQNHESKLNENSKALYRDLVEEKIIPEIKEDGDSDLTIEEIDLIGSHLDKEIEDLNHSIQNEDCTQIRKQTRKKRTEIKKFKKKFDDYSERKSKYEEQKSILKDRNSFSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLSYDLFQNPTDTRTLIPFLTMIQNTFGYLPEYIVADAGYGSEQNYMAIIDDFNKTPLITYGMFIKDKTRKFKSDIFNTQNWKYDELNDEFICPNNKRIGFKRYAYRNDRYGFKRDFKLYECDDCSACSLRQQCMKPNSKSNKKIMKNYNWEYFKAQINQKLSEPETKKIYSQRKIDVEPVFGFMKAILGFTRMSVRGINKVKRELGFVLMALNIRKIVARRAVYYQIHLKKADFYQIINRNQLFYIA
>NZ_CP020467.1|WP_000521495.1|2278259_2279615_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP020467.1|WP_000894028.1|2279641_2280574_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKITGGEEQLNDIAYLKATFKTNKKINGDTKDIAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVSKAEPSETKAYINVK
>NZ_CP020467.1|WP_000347896.1|2280575_2281385_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP020467.1|WP_000162591.1|2281574_2282483_-|arginase
MTKKKGIDIIGVPSTFGQRKLGVDLGPTAIRYAGLIPRLKQLDLDVNDKGDIKVSAVDIEKFQSEQNGLRNYDEIIDVTQKLNKEVSASIENNRFPLVLGGDHSIAIGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLTYRESHFALELLHQSQSVTSMDLVEVNPLIDHNNHTAEQSVSLVGTFFGETLL
>NZ_CP020467.1|WP_000958522.1|2288700_2289765_-|P-loop-NTPase
MLTVDQVKELIGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKVAMAQLGGAPQLDLQMAVVNVLKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGINGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVRWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP020467.1|WP_072435031.1|2291544_2292018_-|multidrug-efflux-transporter-SepA
MVMNYLKHKFYNLLTTIIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIVFAVEHLMDYFRKMLPENAYFRGATFHLISYMVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP020467.1|WP_001237527.1|2292139_2293483_-|MFS-transporter
MRLKSIVTVIALILIMFMAAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLTRFKIIYIAIAGLTLFTVGSLMSGLSTHFSMLVISRVIQGFGSGVMMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVVWTFHFPEEETVAKSKFDTKGITLFYIFIGLIMFALLNQQHLYLNIIGFVLAILVALRLFNVEKKVSSPFLPVAEFNRMITLVFITDLLTAVCLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHHIEAKLSRKVIYLSSFTLLLLSSIIIAFGIKLPILIACVLILSGLSFGYIYTKDSVIVQEETSPIQMKKMMSFYGLTKNLGASIGSTIMGYLYALKSGLFGANLHNILGVVSLISVGLIVVWLIFYREAASQTKE
>NZ_CP020467.1|WP_000047120.1|2293660_2294344_-|hemolysin-III-family-protein
MSKSSEKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAYGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP020467.1|WP_000884730.1|2294362_2295550_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQAKQLKELHRQTGHKIQWYIMTSDINHEETLAYFESHNYFGYDQESIHFFKQDNIVALSEAGQLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
>NZ_CP020467.1|WP_000147093.1|2295593_2296109_-|metal-dependent-hydrolase
MTGKTHASCGMLVGALTTQYFQTDIFSSVTVIILATLASLLPDICHTQSKIGRRFKVISFFVRLIFGHRTFTHSILFIAIIAFLLQIIQTPNYYMAAIIIGLVSHVILDMITPKGVKLFYPLPFNVKTPIQFKTGGLVDLSLATALMIGTVYVLFQPFINDIISNWNTKFL

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Crispr_ID: NZ_CP020467_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_8

2336104-2336229

Orphan

Consensus_repeat	Method
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020467_8

>merge|NZ_CP020467|8|2336104-2336229|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCACTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTTCCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

>NZ_CP020467|8|6|2336104-2336229|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTT
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_107375249.1\|2339968_2340775_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP020467.1\|WP_107375248.1\|2336286_2337723_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225420
NZ_CP020467.1\|WP_001044451.1\|2329160_2330015_-\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP020467.1\|WP_000569649.1\|2345011_2345956_-\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NZ_CP020467.1\|WP_001250038.1\|2338483_2338921_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP020467.1\|WP_000850000.1\|2325851_2326268_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP020467.1\|WP_000136272.1\|2335858_2336038_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236623
NZ_CP020467.1\|WP_000044369.1\|2330225_2331041_-\|HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319792
NZ_CP020467.1\|WP_001791584.1\|2335026_2335209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000769709.1\|2331335_2331761_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_CP020467.1\|WP_000170975.1\|2338071_2338470_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP020467.1\|WP_000130145.1\|2332892_2334557_-\|acetolactate-synthase-AlsS	unknown	unknown	gnl\|CDD\|236312
NZ_CP020467.1\|WP_000542274.1\|2344626_2344995_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
NZ_CP020467.1\|WP_000179061.1\|2332151_2332856_-\|acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
NZ_CP020467.1\|WP_001791582.1\|2326510_2326678_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000586768.1\|2340764_2341625_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184205
NZ_CP020467.1\|WP_001221836.1\|2339169_2339964_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP020467.1\|WP_000222271.1\|2326674_2329101_+\|polysaccharide-lyase-8-family-protein	unknown	unknown	gnl\|CDD\|238517
NZ_CP020467.1\|WP_094409958.1\|2342806_2344374_+\|IS3-like-element-ISSau2-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP020467.1\|WP_000389651.1\|2341621_2342431_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184207

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_107375249.1\|2339968_2340775_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.88772e-48
NZ_CP020467.1\|WP_107375248.1\|2336286_2337723_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	4.4184e-63
NZ_CP020467.1\|WP_001044451.1\|2329160_2330015_-\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.20929e-22
NZ_CP020467.1\|WP_001250038.1\|2338483_2338921_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	4.91074e-100
NZ_CP020467.1\|WP_000850000.1\|2325851_2326268_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.51415e-41
NZ_CP020467.1\|WP_000136272.1\|2335858_2336038_-\|hypothetical-protein	gnl\|CDD\|236623	PRK09775, PRK09775, type II toxin-antitoxin system HipA family toxin YjjJ.	0.0004492
NZ_CP020467.1\|WP_000044369.1\|2330225_2331041_-\|HAD-IIB-family-hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.06188e-100
NZ_CP020467.1\|WP_000569649.1\|2345011_2345956_-\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	1.89947e-175
NZ_CP020467.1\|WP_000769709.1\|2331335_2331761_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	8.17372e-34
NZ_CP020467.1\|WP_000170975.1\|2338071_2338470_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82
NZ_CP020467.1\|WP_000130145.1\|2332892_2334557_-\|acetolactate-synthase-AlsS	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
NZ_CP020467.1\|WP_000542274.1\|2344626_2344995_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
NZ_CP020467.1\|WP_000179061.1\|2332151_2332856_-\|acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.39507e-119
NZ_CP020467.1\|WP_001221836.1\|2339169_2339964_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.21958e-120
NZ_CP020467.1\|WP_000586768.1\|2340764_2341625_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
NZ_CP020467.1\|WP_000222271.1\|2326674_2329101_+\|polysaccharide-lyase-8-family-protein	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
NZ_CP020467.1\|WP_094409958.1\|2342806_2344374_+\|IS3-like-element-ISSau2-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.59839e-44
NZ_CP020467.1\|WP_000389651.1\|2341621_2342431_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0

>NZ_CP020467.1|WP_000136272.1|2335858_2336038_-|hypothetical-protein
MTEIVEFLSDGKLASRLEIQETMGLQKSYTSELIAELKKLEIIGSEGRGPGTRYYLIRD
>NZ_CP020467.1|WP_001791584.1|2335026_2335209_-|hypothetical-protein
MIDSVFWKKAFIPVYFIVAMLVFLLFRFYIKTNNFSIYLMIIFLMCLGTASIIYNYKNNR
>NZ_CP020467.1|WP_000130145.1|2332892_2334557_-|acetolactate-synthase-AlsS
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELETQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEPFINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>NZ_CP020467.1|WP_000179061.1|2332151_2332856_-|acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGAVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIQDEDFINANIDYKDIADEIREAE
>NZ_CP020467.1|WP_000769709.1|2331335_2331761_+|MAP-domain-containing-protein
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNQLASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>NZ_CP020467.1|WP_000044369.1|2330225_2331041_-|HAD-IIB-family-hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITVVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILHHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEVLVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>NZ_CP020467.1|WP_001044451.1|2329160_2330015_-|M23-family-metallopeptidase
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTWQSDVHELKVCTQNDGTIEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNLGKVNADYFCFGKDIIAPANGTVEKVVNGVQDNSIGSTKESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>NZ_CP020467.1|WP_000222271.1|2326674_2329101_+|polysaccharide-lyase-8-family-protein
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTTDYEKLRNIWLDVNYGYDKYDENNPDMKKKFEATENEAEKLLKEMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKISEAMKHKNTKLKTDENKTKVKDALEWLHKNAYGKEPDKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLQEDFTDEEKKKYTAPIKTFAPDSDKILSSVGKSEPAKGGNLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYAQNSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETPFNDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDTMDKSTKAKYKKIVKTSVESDSSYKQTDYLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINGENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANDYKLYKDDTQTTNSDNQETNSLFLESTNSTQNNIGYHFLNESKITVKKESHTGKWSDINKSQKDIQKTDEYYEVTQKHSNTDSKYAYVLYPGLSKDVFKSKASKVTVVKQEDDFHVVKDNESVWAGINYSDSAKTFEINNTKVEVKAKGMFILTKKDDNTYECSFYNPESTNSVSDIESKISMTGYSIINKNTSTSNESGVRFELTK
>NZ_CP020467.1|WP_001791582.1|2326510_2326678_+|hypothetical-protein
MLKIWVIDCLYASTFFVDCLTVDSQLYTLTNFEKLNHYLIIIFIAHAQHKKETCQ
>NZ_CP020467.1|WP_000850000.1|2325851_2326268_-|MerR-family-transcriptional-regulator
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDNDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNHDDNVERLWERK
>NZ_CP020467.1|WP_107375248.1|2336286_2337723_-|MarR-family-transcriptional-regulator
MTSSKYIEYLQTEVEGQLLDRKRASINPKDVVQHISAFANAEGGKLVIGIEDNGEISGFNHSKAKKKEVYIEAPFEHLYRIPKYTYEIIEVKKRDGTMDEILIFDIEPSYDAIITLKDDSVYLRINDKSRKLTHNQITNLEYDRGSRRFEEELVEYSSIEDVNEELVDEFKQLLNTNVDNEKLLKARGFMREGKLTVAGLLLFSNHINVYLPGARIRFMRYEGTKEESGTRLNIVKDITFDKALPVAIREARAFINTQLREYTFLGKEGRFVTLPEYPEFAWFEGMINSIVHRRYDNQGDHIRIKMFDDRLEISSPGALPASVTLENIKEERYSRNPKLAAALTQYKWVRESNEGVGRIFDEMKQYFLDDPVYSEPNNSSVQLALKNNIIARKKRETGRVSNIITPELFESLNEQQELIVRHLYNQGELTASKIANIIQRSVPTARKRLKELEEMNIISTHGSSKNDPKRTYYLLGFE
>NZ_CP020467.1|WP_000170975.1|2338071_2338470_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>NZ_CP020467.1|WP_001250038.1|2338483_2338921_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>NZ_CP020467.1|WP_001221836.1|2339169_2339964_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRIHKRHVRIHPSSRTDRGVHAIQQYFHFDTDLNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQQRDPFQSGLKTFIPEPLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSL
>NZ_CP020467.1|WP_107375249.1|2339968_2340775_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWMFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMGELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVKRTSYRQLKWQLRDTLSLIMIIPIAIILFVLKYSGV
>NZ_CP020467.1|WP_000586768.1|2340764_2341625_-|energy-coupling-factor-transporter-ATPase
MIIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>NZ_CP020467.1|WP_000389651.1|2341621_2342431_-|energy-coupling-factor-transporter-ATPase
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALEQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTATEIFDHAEELTTIGLDLPFPIKINQMLGHQTSFLTYEGLVDQL
>NZ_CP020467.1|WP_094409958.1|2342806_2344374_+|IS3-like-element-ISSau2-family-transposase
MKTLKGALFMSIKPKVDIDVLLYMFQEYEKGVSFQYLIDTLQLDINVNTLYPKYKYYKTHGIETLLTQKQYNHYSKELKLKVVNEYLNSNQSTQDIAIKYNIRSSTQVKNWIKMYTVGKEIKNQSPKTGVYIMKARKTTFEERVTIVEYYLNHKQSYREVAEHFNISYGQIYQWVHKYQAHGKNGLVDGRGKGKPKSMMTPEEQKEAEIQALKAQNRLLEMENDVFKKVSSIGKRDDSKRKQITAYKTIEALKHQYPIQRLCRILGISRASYYKWVHYQSSELELENEQLKREIESIYHKYNGIYGYRRIYIYIRLKLGKQVNRKRIYRLMKELNLKAVIRQKRKPYRRSTPQITSENKLNRQFDIDTPNKVWLTDVTEFKIKEGSKIYLSAIYDLGAKRIVSYELGPSNNNQLVFKTFNQAIEKVENTKGILFHSDRGFQYTSKTFKHMLDECGMIQSMSRVSKCIDNGPMEGVWGTIKSEIFRGNKHFKFNSVEEATKTIHDFILFFNHERITLKMADSV
>NZ_CP020467.1|WP_000542274.1|2344626_2344995_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
>NZ_CP020467.1|WP_000569649.1|2345011_2345956_-|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED

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Crispr_ID: NZ_CP020467_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020467_9

2376111-2376191

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020467_9

>merge|NZ_CP020467|9|2376111-2376191|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGCCAATTTG

>NZ_CP020467|9|7|2376111-2376191|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTTCGTCACCT
TCTATGTTGGGGCCCCGCCAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020467.1\|WP_001573526.1\|2372491_2372743_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000051210.1\|2366640_2366805_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_001791501.1\|2375883_2376054_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000503824.1\|2380981_2381488_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP020467.1\|WP_001161085.1\|2367049_2367367_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020467.1\|WP_000602938.1\|2378681_2379167_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP020467.1\|WP_000259736.1\|2379163_2380423_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP020467.1\|WP_000230171.1\|2376334_2377357_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP020467.1\|WP_000808500.1\|2378221_2378668_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP020467.1\|WP_000951069.1\|2373661_2374102_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP020467.1\|WP_000066900.1\|2375407_2375758_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP020467.1\|WP_000866973.1\|2377982_2378216_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP020467.1\|WP_000134529.1\|2380485_2380980_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP020467.1\|WP_000913006.1\|2382688_2383294_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP020467.1\|WP_000600967.1\|2372734_2373499_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP020467.1\|WP_000592290.1\|2367553_2370721_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP020467.1\|WP_000643988.1\|2377376_2377976_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP020467.1\|WP_000076914.1\|2381516_2382521_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP020467.1\|WP_000413875.1\|2370837_2372103_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP020467.1\|WP_000184409.1\|2374094_2375306_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042

Protein	Function_ID	Function_description	E-value
NZ_CP020467.1\|WP_000866973.1\|2377982_2378216_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	2.40505e-24
NZ_CP020467.1\|WP_000503824.1\|2380981_2381488_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.50849e-64
NZ_CP020467.1\|WP_000602938.1\|2378681_2379167_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	3.19119e-50
NZ_CP020467.1\|WP_000259736.1\|2379163_2380423_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	7.37627e-158
NZ_CP020467.1\|WP_000230171.1\|2376334_2377357_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP020467.1\|WP_000808500.1\|2378221_2378668_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP020467.1\|WP_000951069.1\|2373661_2374102_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.58234e-15
NZ_CP020467.1\|WP_000066900.1\|2375407_2375758_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP020467.1\|WP_000134529.1\|2380485_2380980_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	5.35275e-97
NZ_CP020467.1\|WP_000913006.1\|2382688_2383294_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.03488e-114
NZ_CP020467.1\|WP_000600967.1\|2372734_2373499_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP020467.1\|WP_000592290.1\|2367553_2370721_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP020467.1\|WP_000643988.1\|2377376_2377976_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP020467.1\|WP_000076914.1\|2381516_2382521_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	4.64376e-130
NZ_CP020467.1\|WP_000413875.1\|2370837_2372103_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	2.47464e-141
NZ_CP020467.1\|WP_000184409.1\|2374094_2375306_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.47845e-73

>NZ_CP020467.1|WP_001791501.1|2375883_2376054_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDLECDNNVKEPLKIYYVVILKSGIEMIFS
>NZ_CP020467.1|WP_000066900.1|2375407_2375758_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP020467.1|WP_000184409.1|2374094_2375306_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGVIISLFIKVDFEVTNSKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFAIERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP020467.1|WP_000951069.1|2373661_2374102_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLTEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP020467.1|WP_000600967.1|2372734_2373499_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP020467.1|WP_001573526.1|2372491_2372743_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIALAIIHMGILAHSTYVYLY
>NZ_CP020467.1|WP_000413875.1|2370837_2372103_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSNPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP020467.1|WP_000592290.1|2367553_2370721_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTSMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKTSASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVTTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKIDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP020467.1|WP_001161085.1|2367049_2367367_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP020467.1|WP_000051210.1|2366640_2366805_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP020467.1|WP_000230171.1|2376334_2377357_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATADGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP020467.1|WP_000643988.1|2377376_2377976_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP020467.1|WP_000866973.1|2377982_2378216_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFENLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP020467.1|WP_000808500.1|2378221_2378668_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP020467.1|WP_000602938.1|2378681_2379167_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLTNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP020467.1|WP_000259736.1|2379163_2380423_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSTMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP020467.1|WP_000134529.1|2380485_2380980_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFNWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQLDQ
>NZ_CP020467.1|WP_000503824.1|2380981_2381488_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRNFDTDKGGQCVLQLLQVDNVEVSDAHYTIVKDEKVAITTQVKKWLEEDVDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP020467.1|WP_000076914.1|2381516_2382521_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQNKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIDHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRTACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENTSITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP020467.1|WP_000913006.1|2382688_2383294_-|ATP-binding-cassette-domain-containing-protein
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP020467_9	9.1\|2376136\|31\|NZ_CP020467\|CRISPRCasFinder	2376136-2376166	31	NZ_CP020467.1	1059537-1059567	1	0.968
NZ_CP020467_9	9.1\|2376136\|31\|NZ_CP020467\|CRISPRCasFinder	2376136-2376166	31	NZ_CP020467.1	1676595-1676625	1	0.968
NZ_CP020467_2	2.1\|907457\|26\|NZ_CP020467\|CRISPRCasFinder	907457-907482	26	NZ_CP020467.1	2151824-2151849	2	0.923
NZ_CP020467_2	2.1\|907457\|26\|NZ_CP020467\|CRISPRCasFinder	907457-907482	26	NZ_CP020467.1	2211908-2211933	2	0.923
NZ_CP020467_5	5.1\|2019485\|37\|NZ_CP020467\|CRT	2019485-2019521	37	NZ_CP020467.1	813195-813231	2	0.946
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	256033-256066	2	0.941
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	348015-348048	2	0.941
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	766822-766855	2	0.941
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	1059474-1059507	2	0.941
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	1796505-1796538	2	0.941
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	2376075-2376108	2	0.941
NZ_CP020467_5	5.2\|2019543\|34\|NZ_CP020467\|CRT	2019543-2019576	34	NZ_CP020467.1	2520028-2520061	2	0.941
NZ_CP020467_9	9.1\|2376136\|31\|NZ_CP020467\|CRISPRCasFinder	2376136-2376166	31	NZ_CP020467.1	813319-813349	2	0.935
NZ_CP020467_9	9.1\|2376136\|31\|NZ_CP020467\|CRISPRCasFinder	2376136-2376166	31	NZ_CP020467.1	862588-862618	2	0.935
NZ_CP020467_9	9.1\|2376136\|31\|NZ_CP020467\|CRISPRCasFinder	2376136-2376166	31	NZ_CP020467.1	907418-907448	2	0.935
NZ_CP020467_9	9.1\|2376136\|31\|NZ_CP020467\|CRISPRCasFinder	2376136-2376166	31	NZ_CP020467.1	2008927-2008957	2	0.935

1. spacer 9.1|2376136|31|NZ_CP020467|CRISPRCasFinder matches to position: 1059537-1059567, mismatch: 1, identity: 0.968

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**************************** **

2. spacer 9.1|2376136|31|NZ_CP020467|CRISPRCasFinder matches to position: 1676595-1676625, mismatch: 1, identity: 0.968

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**************************** **

3. spacer 2.1|907457|26|NZ_CP020467|CRISPRCasFinder matches to position: 2151824-2151849, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cgcggccccaacacagaagctggcgg	Protospacer
** ********************.**

4. spacer 2.1|907457|26|NZ_CP020467|CRISPRCasFinder matches to position: 2211908-2211933, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cggggccccaacacaaaagctggcgg	Protospacer
***************.*******.**

5. spacer 5.1|2019485|37|NZ_CP020467|CRT matches to position: 813195-813231, mismatch: 2, identity: 0.946

ccaacttgcacattattgtaagctgacagaaagtcag	CRISPR spacer
ccaacttgcacattattgtaagctggcggaaagtcag	Protospacer
*************************.*.*********

6. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 256033-256066, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

7. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 348015-348048, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaat	Protospacer
************.***********.*********

8. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 766822-766855, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaat	Protospacer
************.***********.*********

9. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 1059474-1059507, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaat	Protospacer
***********.************.*********

10. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 1796505-1796538, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

11. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 2376075-2376108, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

12. spacer 5.2|2019543|34|NZ_CP020467|CRT matches to position: 2520028-2520061, mismatch: 2, identity: 0.941

aacttgcattgtctgtagaatttcctttcgaaat	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaat	Protospacer
************************.***.*****

13. spacer 9.1|2376136|31|NZ_CP020467|CRISPRCasFinder matches to position: 813319-813349, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgactttacgtcagct	Protospacer
********************** ***** **

14. spacer 9.1|2376136|31|NZ_CP020467|CRISPRCasFinder matches to position: 862588-862618, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctggcttttcgtcagct	Protospacer
*****************.********** **

15. spacer 9.1|2376136|31|NZ_CP020467|CRISPRCasFinder matches to position: 907418-907448, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattattgtaagctgacttttcgccagct	Protospacer
*************************.** **

16. spacer 9.1|2376136|31|NZ_CP020467|CRISPRCasFinder matches to position: 2008927-2008957, mismatch: 2, identity: 0.935

cacattattgtaagctgacttttcgtcacct	CRISPR spacer
cacattatcgtaagctgacttttcgtcagct	Protospacer
********.******************* **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

681901 : 699497

Staphylococcus_phage(50.0%)

transposase,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001105942.1\|681901_682576_+\|transposase	IS6-like element ISSau6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.3e-113	88.4
WP_001035802.1\|682610_682823_-	hypothetical protein	NA	NA	NA	NA
WP_000120605.1\|683538_683853_+	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4PQT4	Staphylococcus_phage	4.7e-39	73.1
WP_000153633.1\|683852_685142_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.6e-187	81.1
WP_000358995.1\|685159_685555_+	thioredoxin-dependent arsenate reductase	A0A2H4PQT9	Staphylococcus_phage	8.5e-62	86.3
WP_000726502.1\|685934_686228_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000713732.1\|686302_688237_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000831610.1\|688240_688552_+	YxeA family protein	NA	NA	NA	NA
WP_000593106.1\|688563_689190_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.1e-22	33.7
WP_000277741.1\|689551_691198_+\|transposase	IS1182-like element ISSau3 family transposase	A0ZS58	Staphylococcus_virus	3.5e-295	100.0
WP_001643491.1\|691352_691730_+	recombinase	NA	NA	NA	NA
WP_001582045.1\|691669_691996_+	recombinase	NA	NA	NA	NA
WP_000273007.1\|692062_692563_+	hypothetical protein	NA	NA	NA	NA
WP_000145511.1\|692927_693788_+	replication initiation protein	NA	NA	NA	NA
WP_000761344.1\|693874_694216_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001002795.1\|694430_694526_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_094409958.1\|695025_696593_-\|transposase	IS3-like element ISSau2 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.0e-49	51.8
WP_000277709.1\|697850_699497_+\|transposase	IS1182-like element ISSau3 family transposase	A0ZS58	Staphylococcus_virus	7.9e-295	99.8

DBSCAN-SWA_2

745203 : 753023

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244416.1\|745203_746259_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|746258_746945_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|746919_747393_-	DoxX family protein	NA	NA	NA	NA
WP_001093552.1\|747734_748175_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_107375197.1\|748454_749039_-	hypothetical protein	NA	NA	NA	NA
WP_001062968.1\|749137_749851_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|749854_750274_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|750275_750944_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604508.1\|751294_751888_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	6.8e-39	44.0
WP_107375198.1\|751871_753023_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_3

764995 : 779133

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663016.1\|764995_766054_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	5.7e-20	26.5
WP_000197262.1\|766212_766755_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429002.1\|767306_768224_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	8.2e-07	22.0
WP_031788440.1\|768314_768416_+	hypothetical protein	NA	NA	NA	NA
WP_000193750.1\|768493_769999_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930016.1\|770338_770839_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	2.7e-52	66.2
WP_001068491.1\|770858_771725_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|772526_772925_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|772887_774993_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|775112_776084_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000876311.1\|776460_777432_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
WP_001245566.1\|777418_778375_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	5.5e-06	60.0
WP_000616865.1\|778371_779133_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.2e-17	30.1

DBSCAN-SWA_4

949029 : 996866

Bacillus_virus(25.0%)

bacteriocin,tRNA,holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000121211.1\|949029_949977_-\|transposase	IS30-like element ISSau1 family transposase	Q9MBM9	Staphylococcus_prophage	1.1e-184	100.0
WP_073392975.1\|950091_951561_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001067041.1\|951611_952598_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.8e-15	30.0
WP_000427776.1\|952600_953581_+	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-16	34.1
WP_001574526.1\|953573_954224_+	ABC transporter permease	NA	NA	NA	NA
WP_001180271.1\|954235_955117_+	ABC transporter permease	NA	NA	NA	NA
WP_094409958.1\|955205_956773_-\|transposase	IS3-like element ISSau2 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.0e-49	51.8
WP_000448933.1\|956832_957822_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|958116_958512_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217728.1\|958882_959602_+	adaptor protein MecA	NA	NA	NA	NA
WP_000959276.1\|959722_960709_+	competence protein CoiA	NA	NA	NA	NA
WP_000082722.1\|960756_962565_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	9.3e-47	24.5
WP_000896691.1\|963024_963831_-	DsbA family protein	NA	NA	NA	NA
WP_000214067.1\|963853_964219_-	hypothetical protein	NA	NA	NA	NA
WP_000224620.1\|964322_964916_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242102.1\|965101_965449_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|965465_966101_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|966117_966927_+	NAD kinase	NA	NA	NA	NA
WP_107375204.1\|966923_967778_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000062404.1\|967798_969184_+	magnesium transporter	NA	NA	NA	NA
WP_000395156.1\|969193_971038_+	sodium:proton antiporter	NA	NA	NA	NA
WP_000933195.1\|971315_972086_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|972281_973367_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570704.1\|973708_975277_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_000889176.1\|975419_976178_+	esterase family protein	NA	NA	NA	NA
WP_001060545.1\|976343_977069_+	hypothetical protein	NA	NA	NA	NA
WP_000355329.1\|977070_977922_+	hypothetical protein	NA	NA	NA	NA
WP_000600387.1\|978663_979173_+	hypothetical protein	NA	NA	NA	NA
WP_001794241.1\|979285_980494_-	MFS transporter	NA	NA	NA	NA
WP_000258649.1\|980453_981629_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340133.1\|982060_983545_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001794242.1\|983525_983786_+	hypothetical protein	NA	NA	NA	NA
WP_001049957.1\|983785_985348_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	2.2e-36	28.2
WP_000928413.1\|985649_986453_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001794169.1\|986671_988996_+\|protease	serine protease	W5SAB9	Pithovirus	4.0e-10	26.8
WP_000021872.1\|989012_990371_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414169.1\|990509_992021_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|992509_993079_-	competence protein ComK	NA	NA	NA	NA
WP_000876825.1\|993288_993507_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_107375205.1\|993587_994574_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|994772_994949_+	YkvS family protein	NA	NA	NA	NA
WP_001033867.1\|994963_995566_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_099119695.1\|995866_995944_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_001790623.1\|996482_996584_+	hypothetical protein	NA	NA	NA	NA
WP_001794574.1\|996593_996866_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_5

1034787 : 1043260

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861576.1\|1034787_1035270_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.0e-22	44.7
WP_001010391.1\|1035256_1036381_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174050.1\|1036384_1037089_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	41.6
WP_000848351.1\|1037088_1037352_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666808.1\|1037353_1038025_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032734.1\|1038017_1040207_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.1e-140	39.2
WP_000483716.1\|1040185_1041670_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	8.5e-46	31.4
WP_000030814.1\|1041662_1042691_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	7.6e-62	41.4
WP_000238673.1\|1042693_1043260_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1

DBSCAN-SWA_6

1505478 : 1590374

Staphylococcus_phage(75.71%)

head,capsid,portal,plate,tRNA,holin,integrase,terminase,protease,tail

attL 1515679:1515696|attR 1586432:1586449

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858795.1\|1505478_1506771_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	4.3e-54	30.0
WP_000525060.1\|1507092_1509786_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000049917.1\|1509809_1510781_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361536.1\|1510767_1511970_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.4e-35	42.5
WP_000690024.1\|1511974_1513117_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839927.1\|1513360_1513678_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1514013_1514694_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000154479.1\|1514765_1515353_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000005208.1\|1515342_1515918_-	IDEAL domain-containing protein	G3MAV7	Bacillus_virus	4.6e-08	27.2
1515679:1515696	attL	NA	NA	NA	NA
WP_000389521.1\|1515931_1517176_-	hypothetical protein	NA	NA	NA	NA
WP_000245891.1\|1517182_1518481_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776318.1\|1518490_1519555_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269937.1\|1519580_1520747_-	chorismate synthase	A0A291AU41	Pandoravirus	1.5e-34	32.3
WP_000442480.1\|1521215_1521665_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_001819897.1\|1521756_1522701_-	heptaprenyl diphosphate synthase subunit II	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774679.1\|1522717_1523443_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450555.1\|1523445_1524018_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1524448_1524721_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161753.1\|1524891_1525890_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1525906_1527217_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133953.1\|1527438_1528614_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_001791199.1\|1528870_1529062_-	hypothetical protein	NA	NA	NA	NA
WP_001791200.1\|1529178_1529295_-	hypothetical protein	NA	NA	NA	NA
WP_000644393.1\|1529325_1529985_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681744.1\|1530061_1531030_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1531144_1532131_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_016186859.1\|1532291_1532378_-	hypothetical protein	NA	NA	NA	NA
WP_000069298.1\|1532515_1533976_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902107.1\|1534128_1535508_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.3
WP_001163814.1\|1535497_1536451_-	hypothetical protein	NA	NA	NA	NA
WP_001151997.1\|1536558_1536807_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186908.1\|1536912_1537458_-	ECF transporter S component	NA	NA	NA	NA
WP_001799520.1\|1537736_1537901_-	hypothetical protein	NA	NA	NA	NA
WP_107375222.1\|1538105_1539014_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000913238.1\|1539071_1539977_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000464818.1\|1540066_1540414_-	hypothetical protein	Q4ZCJ7	Staphylococcus_virus	3.0e-26	100.0
WP_000675478.1\|1540658_1541495_-	hypothetical protein	D2JLG6	Staphylococcus_phage	8.4e-152	100.0
WP_000909210.1\|1542110_1543565_-	CHAP domain-containing protein	Q8SDN4	Staphylococcus_virus	7.5e-289	99.8
WP_000339144.1\|1543575_1543878_-\|holin	phage holin	B7T0L0	Staphylococcus_virus	4.1e-48	100.0
WP_061734471.1\|1544013_1544313_-	DUF2951 family protein	M9QRV2	Staphylococcus_phage	1.7e-30	97.0
WP_000916020.1\|1544358_1544523_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1544515_1544905_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_107375223.1\|1544904_1546371_-\|plate	BppU family phage baseplate upper protein	M1TB09	Staphylococcus_phage	9.6e-252	99.2
WP_000429551.1\|1546370_1548281_-	minor structural protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	100.0
WP_000179860.1\|1548296_1548587_-	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_000384474.1\|1548586_1550170_-	peptidase	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_001190533.1\|1550178_1551003_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_070028375.1\|1551002_1557203_-\|tail	phage tail tape measure protein	U5U762	Staphylococcus_phage	0.0e+00	99.6
WP_000438833.1\|1557216_1557375_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589165.1\|1557416_1557767_-	hypothetical protein	A0A2I6PDE6	Staphylococcus_phage	1.1e-55	100.0
WP_000169128.1\|1557824_1558280_-	Ig domain-containing protein	A0A2I6PF45	Staphylococcus_phage	1.3e-77	100.0
WP_000807536.1\|1558371_1559013_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_001023802.1\|1559047_1559443_-	DUF3168 domain-containing protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
WP_000110020.1\|1559443_1559845_-	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
WP_000395501.1\|1559841_1560174_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
WP_000050973.1\|1560185_1560464_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142739.1\|1560532_1561696_-\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
WP_000061872.1\|1561707_1562481_-\|protease	Clp protease ClpP	M1TAZ4	Staphylococcus_phage	9.2e-137	100.0
WP_001100669.1\|1562464_1563703_-\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
WP_000153549.1\|1563707_1565399_-\|terminase	terminase large subunit	A0A2I6PDP8	Staphylococcus_phage	0.0e+00	99.8
WP_000778930.1\|1565388_1565694_-\|terminase	terminase	A0A2I6PDN6	Staphylococcus_phage	3.7e-49	100.0
WP_000196700.1\|1565820_1566135_-	HNH endonuclease	A0A2I6PDR3	Staphylococcus_phage	8.5e-57	100.0
WP_053507569.1\|1566296_1566734_-	transcriptional regulator	A0A2I6PDC2	Staphylococcus_phage	7.9e-77	98.6
WP_078066162.1\|1566746_1568114_-	DEAD/DEAH box helicase	A0A2I6PDQ0	Staphylococcus_phage	1.3e-263	99.8
WP_000665204.1\|1568094_1568385_-	VRR-NUC domain-containing protein	A0A2I6PDQ7	Staphylococcus_phage	4.9e-51	100.0
WP_015978074.1\|1568518_1568623_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
WP_107375224.1\|1568725_1571173_-	hypothetical protein	M1RZC5	Staphylococcus_phage	0.0e+00	98.7
WP_000265258.1\|1571224_1571425_-	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000595237.1\|1571492_1571645_-	transcriptional activator RinB	B5WZN3	Staphylococcus_phage	2.6e-19	100.0
WP_000483477.1\|1571637_1571874_-	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
WP_000195831.1\|1571898_1572135_-	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	1.1e-35	100.0
WP_107375225.1\|1572171_1572708_-	dUTPase	A0A1P8L6E0	Staphylococcus_phage	2.3e-94	98.9
WP_107375226.1\|1572700_1572949_-	DUF1024 family protein	Q9B0F3	Staphylococcus_virus	7.7e-37	96.3
WP_000131377.1\|1572963_1573206_-	hypothetical protein	R9QT89	Staphylococcus_phage	3.0e-41	100.0
WP_000152769.1\|1573763_1573919_-	hypothetical protein	A0A2I6PDP0	Staphylococcus_phage	3.5e-19	94.1
WP_107375269.1\|1573930_1575883_-	DNA polymerase	M1SVE1	Staphylococcus_phage	0.0e+00	99.7
WP_000645048.1\|1575950_1576508_-	DUF2815 family protein	A0A2I6PEP8	Staphylococcus_phage	1.8e-97	100.0
WP_031834538.1\|1576533_1577700_-	DUF2800 domain-containing protein	M1T2Z7	Staphylococcus_phage	8.3e-222	100.0
WP_000985976.1\|1577696_1578059_-	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	4.9e-56	100.0
WP_000174994.1\|1578073_1578397_-	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
WP_001285954.1\|1578475_1578637_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124160.1\|1578649_1578913_-	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_001097552.1\|1578937_1579153_-	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001128433.1\|1579207_1579573_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001025401.1\|1579541_1579787_-	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_001148544.1\|1579815_1580592_-	Rha family transcriptional regulator	A0A2I6PD87	Staphylococcus_phage	1.1e-140	100.0
WP_001121027.1\|1580605_1580842_-	helix-turn-helix transcriptional regulator	A0A2I6PD81	Staphylococcus_phage	1.5e-37	100.0
WP_000333630.1\|1580993_1581308_+	helix-turn-helix transcriptional regulator	A0A0N9BAW4	Staphylococcus_phage	9.8e-53	100.0
WP_000525004.1\|1581320_1581782_+	hypothetical protein	A0A2K9VBR7	Staphylococcus_phage	1.2e-83	100.0
WP_000825948.1\|1581799_1582384_+	hypothetical protein	A0A2I6PD77	Staphylococcus_phage	1.4e-68	100.0
WP_001166482.1\|1582722_1583346_-	hypothetical protein	B7T0F3	Staphylococcus_virus	9.8e-105	99.5
WP_000264191.1\|1583455_1584661_+\|integrase	site-specific integrase	M1RZA8	Staphylococcus_phage	1.0e-222	100.0
WP_001794062.1\|1584703_1586746_-	hypothetical protein	B5WZK7	Staphylococcus_phage	1.1e-38	44.1
1586432:1586449	attR	NA	NA	NA	NA
WP_001574168.1\|1586732_1587665_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000987777.1\|1587916_1589668_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
WP_000064078.1\|1589648_1590374_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-45	43.0

DBSCAN-SWA_7

1648215 : 1656527

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1648215_1649001_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924211.1\|1649126_1650017_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062173.1\|1650026_1651373_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	1.4e-55	34.0
WP_000683921.1\|1651486_1652587_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	3.0e-08	30.6
WP_000624581.1\|1652589_1653267_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1653397_1654504_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217253.1\|1654727_1656527_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_8

1725963 : 1735006

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1725963_1726482_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000595001.1\|1726503_1728777_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.2e-64	29.3
WP_000749802.1\|1728979_1731259_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1731533_1731794_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1731812_1732952_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1732974_1734000_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1734001_1735006_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_9

1864731 : 1933637

Staphylococcus_phage(93.02%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_107375234.1\|1864731_1871301_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.7e-295	88.7
WP_000836472.1\|1871624_1871936_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
WP_001108722.1\|1871957_1874372_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.8
WP_107375235.1\|1874663_1875845_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	8.1e-217	99.5
WP_000526541.1\|1875954_1876908_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	6.4e-79	99.3
WP_000764425.1\|1876904_1877468_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	1.1e-99	95.7
WP_000757543.1\|1877586_1877988_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266099.1\|1878560_1879388_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1879390_1879510_-	hypothetical protein	NA	NA	NA	NA
WP_001196351.1\|1879621_1880623_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	5.0e-183	99.1
WP_001008556.1\|1880744_1881209_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.9e-68	97.4
WP_001159032.1\|1881221_1882403_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_000493891.1\|1882413_1883046_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.4e-112	99.0
WP_001819953.1\|1883052_1884084_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.8e-195	98.3
WP_001261683.1\|1884576_1886079_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	5.0e-30	98.6
WP_000221181.1\|1886721_1887036_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.7e-52	97.1
WP_000989104.1\|1887035_1888328_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	2.6e-216	95.1
WP_001032833.1\|1888414_1889269_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1889544_1889769_-	hypothetical protein	NA	NA	NA	NA
WP_000671059.1\|1889967_1890438_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	7.7e-70	85.8
WP_001152695.1\|1890550_1890994_+	competence protein ComK	NA	NA	NA	NA
WP_001030476.1\|1890980_1891424_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-49	77.4
WP_001168914.1\|1891721_1892357_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000492901.1\|1892523_1893144_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001096494.1\|1893601_1894315_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091444.1\|1894573_1894876_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1895130_1895496_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623481.1\|1895492_1895846_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	4.2e-20	97.4
WP_000453316.1\|1896095_1896929_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-158	99.6
WP_000366165.1\|1897140_1898049_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
WP_000933819.1\|1898173_1899367_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
WP_000109909.1\|1899738_1901331_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_001801476.1\|1901623_1902370_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	3.3e-139	97.2
WP_000672010.1\|1902374_1902848_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	9.5e-84	98.1
WP_000718107.1\|1902913_1903171_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778539.1\|1903167_1904169_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.5e-183	96.7
WP_000348372.1\|1904173_1905652_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.4e-282	97.2
WP_016186903.1\|1905810_1906266_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.5e-75	94.5
WP_001794016.1\|1906567_1907218_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	1.0e-51	88.4
WP_000070654.1\|1907298_1908294_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	3.8e-74	97.2
WP_000669038.1\|1908369_1908996_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	4.5e-81	84.1
WP_000627550.1\|1909036_1909381_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	5.1e-55	94.7
WP_000414222.1\|1909478_1910051_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
WP_001794355.1\|1910199_1911141_-	FRG domain-containing protein	NA	NA	NA	NA
WP_107375236.1\|1911157_1911568_-	hypothetical protein	NA	NA	NA	NA
WP_000125075.1\|1911567_1912137_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.2e-39	54.8
WP_000747804.1\|1912329_1912776_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001801861.1\|1913226_1913322_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791232.1\|1913444_1913546_+	hypothetical protein	NA	NA	NA	NA
WP_001037039.1\|1913720_1914164_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000731421.1\|1914163_1914607_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000182553.1\|1915573_1917994_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_001819963.1\|1918119_1918479_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000619920.1\|1918706_1919156_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001053714.1\|1919198_1920809_+	hypothetical protein	NA	NA	NA	NA
WP_000095390.1\|1920823_1921123_+	secretion protein	NA	NA	NA	NA
WP_000072622.1\|1923237_1924392_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	7.8e-39	36.3
WP_001794363.1\|1924384_1926124_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.2e-286	98.6
WP_001038742.1\|1926303_1927023_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
WP_001038734.1\|1927192_1927909_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	6.6e-129	97.1
WP_001038766.1\|1928954_1929671_-\|protease	serine protease	A0A2H4PQN5	Staphylococcus_phage	5.5e-83	62.6
WP_001039022.1\|1929794_1930514_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	6.4e-124	93.7
WP_000595635.1\|1931528_1932044_+	membrane protein	NA	NA	NA	NA
WP_000711499.1\|1932290_1933637_+	DUF4041 domain-containing protein	M1NRY5	Streptococcus_phage	2.5e-65	51.1

DBSCAN-SWA_10

2020144 : 2131804

137

Staphylococcus_phage(83.51%)

head,capsid,terminase,portal,coat,tRNA,holin,integrase,transposase,protease,tail

attL 2120617:2120633|attR 2131540:2131556

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000545373.1\|2020144_2021572_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000027924.1\|2021584_2023042_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|2023043_2023346_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957023.1\|2023712_2025251_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831695.1\|2025339_2026539_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774552.1\|2026551_2028555_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	9.8e-114	36.1
WP_107375238.1\|2028558_2030751_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.4e-134	42.1
WP_000272063.1\|2030747_2031440_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2031611_2031914_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2032022_2033318_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827736.1\|2034168_2035335_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434532.1\|2035365_2035689_+	staphostatin A	NA	NA	NA	NA
WP_000669861.1\|2035982_2036156_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2036136_2036739_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040861.1\|2037008_2037830_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284434.1\|2037822_2039292_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	8.5e-107	44.5
WP_000897633.1\|2039475_2040552_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177832.1\|2040571_2041366_+	prephenate dehydratase	NA	NA	NA	NA
WP_031788442.1\|2041437_2041545_+	hypothetical protein	NA	NA	NA	NA
WP_000323171.1\|2041555_2043118_-	SLC13 family permease	NA	NA	NA	NA
WP_000275719.1\|2043322_2044420_-	pectate lyase	U5PWM6	Bacillus_phage	8.7e-48	34.6
WP_000149686.1\|2044792_2045353_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2045405_2046335_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2046527_2046701_-	hypothetical protein	NA	NA	NA	NA
WP_001021224.1\|2046752_2048132_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|2048251_2049280_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2049550_2049952_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2050008_2050182_-	hypothetical protein	NA	NA	NA	NA
WP_001188074.1\|2050632_2051673_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713064.1\|2051729_2052572_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033968.1\|2052568_2053126_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2053185_2053710_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2053830_2054394_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221650.1\|2054457_2055198_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2055197_2056070_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645732.1\|2056066_2056747_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991315.1\|2056747_2057644_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2057640_2058021_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681966.1\|2058278_2058455_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2058696_2058795_-	hypothetical protein	NA	NA	NA	NA
WP_001068528.1\|2058994_2060281_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_107375185.1\|2060528_2062148_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	4.6e-287	97.8
WP_000669728.1\|2062445_2064515_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669789.1\|2065472_2065652_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1\|2065962_2066223_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|2066275_2066626_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000727649.1\|2067310_2067760_+	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_020444758.1\|2067854_2068313_-	amidase	R9QTN8	Staphylococcus_phage	4.9e-85	98.7
WP_000919350.1\|2068839_2069331_-	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
WP_107375239.1\|2069521_2070277_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	9.9e-152	99.6
WP_000611512.1\|2070288_2070543_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_001791821.1\|2070594_2070702_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|2070754_2070931_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000539688.1\|2071080_2071377_-	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_001040261.1\|2071434_2071722_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_001153681.1\|2071768_2071921_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_107375240.1\|2071910_2075696_-	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.7
WP_107375241.1\|2075711_2077196_-\|tail	phage tail protein	A0A2I6PDJ0	Staphylococcus_phage	1.7e-296	99.8
WP_001644871.1\|2077192_2081722_-\|tail	phage tail tape measure protein	A0A1X9H017	Staphylococcus_phage	0.0e+00	100.0
WP_001096353.1\|2081966_2082317_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	3.0e-58	99.1
WP_100209307.1\|2082366_2082672_-	hypothetical protein	A0A075LYE8	Staphylococcus_phage	7.8e-31	97.3
WP_000268737.1\|2082632_2083274_-\|tail	phage tail protein	C8CH27	Staphylococcus_phage	1.0e-117	99.1
WP_000565498.1\|2083274_2083682_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114341.1\|2083678_2084083_-	hypothetical protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-69	100.0
WP_000755150.1\|2084079_2084442_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000150936.1\|2084425_2084710_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_070992243.1\|2084699_2084984_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	8.8e-45	98.9
WP_107375242.1\|2085003_2086149_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	1.6e-214	99.7
WP_000642728.1\|2086172_2086910_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025274.1\|2086893_2088081_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|2088096_2089758_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|2089754_2090099_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988336.1\|2090229_2090529_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000590122.1\|2090760_2091177_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000265042.1\|2091204_2091405_-	DUF1514 family protein	A0A2I6PDJ9	Staphylococcus_phage	1.4e-28	100.0
WP_001005262.1\|2091404_2092055_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
WP_000501856.1\|2092213_2092378_-	transcriptional activator RinB	A0A2I6PDY4	Staphylococcus_phage	3.9e-21	100.0
WP_001125015.1\|2092365_2092566_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195782.1\|2092540_2092729_-	DUF1381 domain-containing protein	A0A2I6PDV0	Staphylococcus_phage	2.1e-26	100.0
WP_001282074.1\|2092725_2092971_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_015978051.1\|2093007_2093535_-	ORF024	O80091	Staphylococcus_phage	8.6e-94	100.0
WP_001065065.1\|2093509_2093758_-	DUF1024 family protein	O80090	Staphylococcus_phage	3.1e-38	100.0
WP_015994229.1\|2093798_2094047_-	hypothetical protein	A0A1X9H0L3	Staphylococcus_phage	2.7e-42	100.0
WP_000235325.1\|2094055_2094256_-	hypothetical protein	C5I650	Staphylococcus_phage	5.6e-30	100.0
WP_000022720.1\|2094258_2094516_-	DUF3310 domain-containing protein	A0A1X9H067	Staphylococcus_phage	5.7e-43	100.0
WP_001140291.1\|2094515_2094887_-	hypothetical protein	C5I648	Staphylococcus_phage	2.7e-57	100.0
WP_001187244.1\|2094887_2095073_-	DUF3113 family protein	A0A2H4JAM6	uncultured_Caudovirales_phage	5.4e-27	100.0
WP_015997090.1\|2095077_2095482_-	DUF1064 domain-containing protein	C5I647	Staphylococcus_phage	1.6e-68	100.0
WP_001123688.1\|2095491_2095713_-	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_000256597.1\|2095725_2095884_-	hypothetical protein	Q4ZBL5	Staphylococcus_phage	3.4e-22	100.0
WP_000803070.1\|2095877_2096657_-	ATP-binding protein	A0A1X9H042	Staphylococcus_phage	1.4e-145	100.0
WP_064289498.1\|2096666_2097458_-	replication protein	A0A2H4JCF5	uncultured_Caudovirales_phage	7.1e-84	73.0
WP_001644874.1\|2097429_2098122_-	hypothetical protein	A0A1X9H044	Staphylococcus_phage	1.0e-131	100.0
WP_000704705.1\|2098134_2098686_-	single-stranded DNA-binding protein	Q4ZBM4	Staphylococcus_phage	3.4e-101	100.0
WP_001644875.1\|2098714_2099503_-	ATP-binding protein	A0A1X9H046	Staphylococcus_phage	2.6e-142	100.0
WP_000815403.1\|2099495_2099717_-	DUF2483 domain-containing protein	A0A1X9H047	Staphylococcus_phage	1.2e-33	100.0
WP_001644876.1\|2099726_2099987_-	DUF1108 family protein	A0A1X9H043	Staphylococcus_phage	5.8e-43	100.0
WP_000138304.1\|2099967_2100297_-	hypothetical protein	D2JGJ7	Staphylococcus_phage	1.4e-33	100.0
WP_000066017.1\|2100386_2100548_-	DUF1270 domain-containing protein	D2JGJ6	Staphylococcus_phage	4.3e-20	100.0
WP_001120197.1\|2100544_2100865_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000435341.1\|2101485_2101746_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000639923.1\|2101758_2102001_-	DUF739 family protein	A0A1X9H035	Staphylococcus_phage	1.6e-39	100.0
WP_001083975.1\|2102164_2102881_+	helix-turn-helix domain-containing protein	A0A1X9H038	Staphylococcus_phage	5.4e-131	100.0
WP_001557601.1\|2102892_2103747_+	restriction endonuclease	A0A1X9H037	Staphylococcus_phage	7.3e-151	100.0
WP_000100503.1\|2103963_2104149_+	hypothetical protein	A0A1X9H0K5	Staphylococcus_phage	1.1e-24	100.0
WP_000705240.1\|2104348_2104531_+	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_064128183.1\|2104608_2105322_+	toxin MazF	A0A1X9H026	Staphylococcus_phage	1.9e-128	99.6
WP_000857198.1\|2105512_2106550_+\|integrase	site-specific integrase	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
WP_000595617.1\|2107687_2108707_-	beta-channel forming cytolysin	A0A2I6PEU3	Staphylococcus_phage	3.4e-54	39.6
WP_000791402.1\|2108728_2109784_-	succinyl-diaminopimelate desuccinylase	A0A2I6PER8	Staphylococcus_phage	7.9e-38	34.6
WP_000206618.1\|2110215_2111439_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_001045073.1\|2111877_2113185_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_001573771.1\|2113762_2114104_-	hypothetical protein	C8CH40	Staphylococcus_phage	4.1e-20	46.0
WP_001573769.1\|2114093_2114390_-	hypothetical protein	C8CH40	Staphylococcus_phage	6.7e-11	40.4
WP_000201397.1\|2114386_2114566_-	hypothetical protein	NA	NA	NA	NA
WP_001239269.1\|2115684_2116620_+	TDT family transporter	NA	NA	NA	NA
WP_000812237.1\|2117474_2117702_-	hypothetical protein	A0A2H4JAH5	uncultured_Caudovirales_phage	1.9e-13	47.4
WP_107375243.1\|2118120_2118825_+	toxic shock syndrome toxin TSST-1	NA	NA	NA	NA
WP_001293073.1\|2118979_2119549_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	3.5e-101	98.4
WP_000358778.1\|2119545_2119887_-	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.7e-58	100.0
WP_000771368.1\|2119889_2120417_-\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
WP_000448775.1\|2120467_2120686_-	hypothetical protein	NA	NA	NA	NA
2120617:2120633	attL	NA	NA	NA	NA
WP_000846285.1\|2120703_2121282_-	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
WP_001190608.1\|2121293_2121635_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	7.1e-57	98.2
WP_001019766.1\|2122170_2122812_-	hypothetical protein	Q4ZE67	Staphylococcus_phage	3.5e-113	94.8
WP_000356937.1\|2122808_2123189_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	6.9e-69	100.0
WP_000447451.1\|2123500_2125210_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	0.0e+00	100.0
WP_001103930.1\|2126142_2126460_-	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	1.6e-18	58.2
WP_000403839.1\|2126460_2126844_-	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	9.7e-63	96.1
WP_001231378.1\|2126845_2127049_-	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	7.5e-30	97.0
WP_000708433.1\|2127033_2127189_-	hypothetical protein	NA	NA	NA	NA
WP_000481967.1\|2127185_2127503_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000153640.1\|2127507_2127726_-	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000620857.1\|2127898_2128573_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_000179345.1\|2128586_2129759_+\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	3.5e-220	98.2
WP_107375244.1\|2129827_2131444_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
WP_000917289.1\|2131519_2131804_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
2131540:2131556	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020467

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection