CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP025563	Listeria monocytogenes strain PIR00544 plasmid p2PIR00544, complete sequence	0 crisprs	NA	0
NZ_CP025565	Listeria monocytogenes strain PIR00544 chromosome, complete genome	3 crisprs	DinG,cas3,WYL,casR,DEDDh,csa3	5
NZ_CP025562	Listeria monocytogenes strain PIR00544 plasmid p1PIR00544, complete sequence	0 crisprs	csa3	0
NZ_CP025564	Listeria monocytogenes strain PIR00544 plasmid p3PIR00544, complete sequence	0 crisprs	NA	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025565_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025565_1

213690-213844

Unclear

Consensus_repeat	Method
TTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP025565_1

>merge|NZ_CP025565|1|213690-213844|CRISPRCasFinder
TTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACACCGATGCTTCTTGGTTTTAATGCTCCTGCTACATCGGAACCGAGCTCATTCGAATTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC

>NZ_CP025565|1|1|213690-213844|CRISPRCasFinder
TTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC	ACCGATGCTTCTTGGTTTTAATGCTCCTGCTACATCGGAACCGAGCTCATTCGAA
TTTCCACCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025565.1\|WP_003726703.1\|208045_208999_-\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NZ_CP025565.1\|WP_003722740.1\|219149_219773_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP025565.1\|WP_003734710.1\|204635_206009_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_CP025565.1\|WP_003722726.1\|203940_204249_+\|septation-protein-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP025565.1\|WP_003725736.1\|217162_217894_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_CP025565.1\|WP_003725730.1\|211165_212698_+\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NZ_CP025565.1\|WP_003725738.1\|220553_221114_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP025565.1\|WP_003725737.1\|219862_220447_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP025565.1\|WP_003734712.1\|214852_215722_+\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NZ_CP025565.1\|WP_003734713.1\|215793_216117_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340321
NZ_CP025565.1\|WP_003722729.1\|207059_207773_-\|listeriolysin-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736
NZ_CP025565.1\|WP_003728174.1\|209241_210831_+\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NZ_CP025565.1\|WP_003722728.1\|206059_207016_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP025565.1\|WP_003722725.1\|203513_203822_+\|septation-protein-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP025565.1\|WP_003722723.1\|200932_201625_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP025565.1\|WP_003725507.1\|201621_202830_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|182528
NZ_CP025565.1\|WP_003725734.1\|216249_216711_+\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NZ_CP025565.1\|WP_003725735.1\|216763_217096_-\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NZ_CP025565.1\|WP_003722739.1\|217914_218856_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NZ_CP025565.1\|WP_003728167.1\|221227_224767_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118

Protein	Function_ID	Function_description	E-value
NZ_CP025565.1\|WP_003726703.1\|208045_208999_-\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	1.53279e-112
NZ_CP025565.1\|WP_003722740.1\|219149_219773_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NZ_CP025565.1\|WP_003734710.1\|204635_206009_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP025565.1\|WP_003722726.1\|203940_204249_+\|septation-protein-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NZ_CP025565.1\|WP_003725736.1\|217162_217894_-\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	1.88663e-21
NZ_CP025565.1\|WP_003725730.1\|211165_212698_+\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	3.62455e-140
NZ_CP025565.1\|WP_003725738.1\|220553_221114_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	1.72721e-108
NZ_CP025565.1\|WP_003725737.1\|219862_220447_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.9401e-09
NZ_CP025565.1\|WP_003734712.1\|214852_215722_+\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	6.38793e-86
NZ_CP025565.1\|WP_003734713.1\|215793_216117_+\|hypothetical-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	1.23896e-43
NZ_CP025565.1\|WP_003722729.1\|207059_207773_-\|listeriolysin-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12
NZ_CP025565.1\|WP_003728174.1\|209241_210831_+\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	7.22171e-179
NZ_CP025565.1\|WP_003722728.1\|206059_207016_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP025565.1\|WP_003722725.1\|203513_203822_+\|septation-protein-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NZ_CP025565.1\|WP_003722723.1\|200932_201625_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121
NZ_CP025565.1\|WP_003725507.1\|201621_202830_+\|FtsX-like-permease-family-protein	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.06393e-62
NZ_CP025565.1\|WP_003725734.1\|216249_216711_+\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	1.52192e-59
NZ_CP025565.1\|WP_003725735.1\|216763_217096_-\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NZ_CP025565.1\|WP_003722739.1\|217914_218856_-\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NZ_CP025565.1\|WP_003728167.1\|221227_224767_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0

>NZ_CP025565.1|WP_003725730.1|211165_212698_+|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFNMAVKADSVGEERLRNNIQAKRNPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSDGYLTDNDEIKVHVTPDNKIAFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYIGNPVKEKEIIINSRTKRLVYNIKLIFAEPEVASWIIQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLNHKTDASFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYDYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGREILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGLRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHFNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKAQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NZ_CP025565.1|WP_003728174.1|209241_210831_+|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENLISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPIAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEINYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNSVDNPIE
>NZ_CP025565.1|WP_003726703.1|208045_208999_-|phosphatidylinositol-specific-phospholipase-C
MYKNYLQRTLVLVLCFILCFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTSLAALSIPGTHDTMSYNGDMTWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLKIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLVINSHKFGMQFGASNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NZ_CP025565.1|WP_003722729.1|207059_207773_-|listeriolysin-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NZ_CP025565.1|WP_003722728.1|206059_207016_+|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NZ_CP025565.1|WP_003734710.1|204635_206009_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQEEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASRLMQRRINENHMRNGVTLVNPENTYIDIDVKIGQDTVIEPGVMLRGETVIGDDCVVTTGSEIVNSVIGERVYVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPDDALGIARAKQDNKLGYAKHLNHGK
>NZ_CP025565.1|WP_003722726.1|203940_204249_+|septation-protein-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NZ_CP025565.1|WP_003722725.1|203513_203822_+|septation-protein-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NZ_CP025565.1|WP_003725507.1|201621_202830_+|FtsX-like-permease-family-protein
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKNSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGIIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NZ_CP025565.1|WP_003722723.1|200932_201625_+|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA
>NZ_CP025565.1|WP_003734712.1|214852_215722_+|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPVTIKASACCDEYLKPPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVDHMRANLMNELKNFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDKDNTYLPGFANAKITGAKYFNQSVADYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVVKRFCSNDVKEWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NZ_CP025565.1|WP_003734713.1|215793_216117_+|hypothetical-protein
MYIKGGLIFFFVMFVIALCSVLILLIIKMSVWKEEPFNLSDAKEIECLGSCKIKNTNQKIHFFSIKKNLFEEEGNMAGILNEHERKGADKSIFIVILDDEKGIANEE
>NZ_CP025565.1|WP_003725734.1|216249_216711_+|YehR-family-lipoprotein
MKMLKKGTTVLFVMIMAVMLVACGDKEETKTYSLSQNGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NZ_CP025565.1|WP_003725735.1|216763_217096_-|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NZ_CP025565.1|WP_003725736.1|217162_217894_-|DNA-alkylation-repair-protein
MRLRMLFLLYLIYSRGVTRTITFDQLNTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVELIESNNSDLIYLGLLAINPDKITTEQIEKWNIIFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAEALLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NZ_CP025565.1|WP_003722739.1|217914_218856_-|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NZ_CP025565.1|WP_003722740.1|219149_219773_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NZ_CP025565.1|WP_003725737.1|219862_220447_+|GNAT-family-N-acetyltransferase
MLDKSVPHISAIMVNHDATNYPEFHLPEGYSFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLAKRCVFVEAPNGEIIGTAMLWDGNTFGEMASRIHWVAVLDSHGGKGIAKALLSKILGLNKSSFVYLTTQTGSYQAIYLYQKFGFEKYVGKTPENWKTVNFQEEKEAAWQIIENKIAEHQA
>NZ_CP025565.1|WP_003725738.1|220553_221114_+|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVIHYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NZ_CP025565.1|WP_003728167.1|221227_224767_+|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMTHTLNELKENEDKQALVENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYFPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEANHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVHALEVGIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKERASAEN

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Crispr_ID: NZ_CP025565_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025565_2

527724-527902

Orphan

Consensus_repeat	Method
TTAAGCAGTTTTGATACGAGCTC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP025565_2

>merge|NZ_CP025565|2|527724-527902|CRISPRCasFinder
GTAAGCAAATTTGATACCAGCTCTGTTACTTTTATGCAGATGATGTTTCAATATTGTAAATCGCTTGAGAAACTGAATTTAAGCAGTTTTGATACGAGCTCAGTAACTCGCATGAATAGTATGTTTGAAGGATGTACTAGTTTTGAAGAGCTAGACTTAAGCAGTTTTGATACGAGTTC

>NZ_CP025565|2|2|527724-527902|CRISPRCasFinder
GTAAGCAAATTTGATACCAGCTC	TGTTACTTTTATGCAGATGATGTTTCAATATTGTAAATCGCTTGAGAAACTGAAT
TTAAGCAGTTTTGATACGAGCTC	AGTAACTCGCATGAATAGTATGTTTGAAGGATGTACTAGTTTTGAAGAGCTAGAC
TTAAGCAGTTTTGATACGAGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025565.1\|WP_012681110.1\|537156_537984_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573
NZ_CP025565.1\|WP_003734772.1\|533414_534032_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003740435.1\|532031_532337_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP025565.1\|WP_003734774.1\|535092_535335_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003725189.1\|520544_521828_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP025565.1\|WP_020830750.1\|532412_532679_+\|transposase	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734775.1\|535417_536395_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP025565.1\|WP_003728093.1\|521828_522929_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP025565.1\|WP_003721252.1\|531025_531499_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734991.1\|528890_530960_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP025565.1\|WP_003734773.1\|534341_534689_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734632.1\|513530_514286_-\|DUF4866-domain-containing-protein	unknown	unknown	gnl\|CDD\|379782
NZ_CP025565.1\|WP_014929029.1\|525105_526644_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP025565.1\|WP_003725184.1\|512844_513510_-\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|226146
NZ_CP025565.1\|WP_003721242.1\|517711_518659_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP025565.1\|WP_107681183.1\|522921_524472_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP025565.1\|WP_003740428.1\|518814_520410_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP025565.1\|WP_003734634.1\|516558_517707_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP025565.1\|WP_003734633.1\|514402_516562_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP025565.1\|WP_010958986.1\|531518_532004_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025565.1\|WP_012681110.1\|537156_537984_+\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	0.00019582
NZ_CP025565.1\|WP_003740435.1\|532031_532337_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.51255e-05
NZ_CP025565.1\|WP_003725189.1\|520544_521828_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP025565.1\|WP_003734775.1\|535417_536395_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	3.2717e-43
NZ_CP025565.1\|WP_003728093.1\|521828_522929_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP025565.1\|WP_003734991.1\|528890_530960_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.65689e-31
NZ_CP025565.1\|WP_003734632.1\|513530_514286_-\|DUF4866-domain-containing-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
NZ_CP025565.1\|WP_014929029.1\|525105_526644_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	9.23286e-20
NZ_CP025565.1\|WP_003725184.1\|512844_513510_-\|DUF1275-domain-containing-protein	gnl\|CDD\|226146	COG3619, COG3619, Predicted membrane protein [Function unknown].	1.87997e-68
NZ_CP025565.1\|WP_003721242.1\|517711_518659_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP025565.1\|WP_107681183.1\|522921_524472_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	4.3062e-106
NZ_CP025565.1\|WP_003740428.1\|518814_520410_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP025565.1\|WP_003734634.1\|516558_517707_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.03616e-53
NZ_CP025565.1\|WP_003734633.1\|514402_516562_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.58381e-28

>NZ_CP025565.1|WP_014929029.1|525105_526644_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLSSFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNNNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLTSDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEILNQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>NZ_CP025565.1|WP_107681183.1|522921_524472_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDLELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP025565.1|WP_003728093.1|521828_522929_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP025565.1|WP_003725189.1|520544_521828_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP025565.1|WP_003740428.1|518814_520410_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP025565.1|WP_003721242.1|517711_518659_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP025565.1|WP_003734634.1|516558_517707_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLVDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP025565.1|WP_003734633.1|514402_516562_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVALLALVIIFRRRIRSYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFGTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP025565.1|WP_003734632.1|513530_514286_-|DUF4866-domain-containing-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NZ_CP025565.1|WP_003725184.1|512844_513510_-|DUF1275-domain-containing-protein
MARSRQISESIGLGLLLALAGGFMDAYSYIERGQVFANAQTGNILLFGINISEGNWAIAIQYFWPVVSFTVGIAISEVIHRRDIRRLHWRQLSVLIEAVILIGVAFIPLDHNLIANSLISFVCGIQVESFRKMHGRGVATTMCIGNLRSATQNLCDYFEYKEKQYLRNSLLYFTVILSFIIGAVVGNFFIQLFAQYAILVCAFLQFIAFMMMFIDRESKII
>NZ_CP025565.1|WP_003734991.1|528890_530960_+|BspA-family-leucine-rich-repeat-surface-protein
MKKLSMRVILIVTVIFIAFGSANVSIAQERDTINKLPEVELGSLYTSNLITEEVAQDKPAEVENLEEAPTTDDLVQNPDVLEQLIADSDDSDLTVVNSGDFWTIYRNTVNGEYSLHMFGNVPSSKPTAWNSYLNRIKHIEIEEATLTGNFSSYFRNNVFTVLESVRIERSNLSRVTSFALAFYGSGIEKVIIRDNNYPTAPSLLTTEGMFKNCSNLMEVDLSGLDTSAVTTMWDMFNSCRALEELDVSHFDTSSVTNMSYMFYDNRNLEVLDVSNLDTSSVTNMYAMFEDCTSLEELDVSNFDTSSVTDMYRVFNGCEKLKKLDVSNFDTSSATEMVQMFRNCSALEKLDVSNFNTSLVTDMRAMFAGCTSLEALDVSNFDTSSVTNMAAMFSDNEKLEKLDLSTFDTSSVTNMGTMFKNCTALKSLFLDNFTHAASSTDMFTGTTSLTYLFVSHNVSNFNGLENTSWYDEKNWVQFSNLSQLQTYHRQQSEPIGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEASELKVQGINRGSKTLSVGLNYEETTISESNKLTLANTADTTVQCLAPLSWDGSETNPEKAILTLAPGSEITEGEAVMVIEAPENIQAGKYTGNVVFSIKYE
>NZ_CP025565.1|WP_003721252.1|531025_531499_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP025565.1|WP_010958986.1|531518_532004_+|hypothetical-protein
MNKLVLSTLSVAAMGMVIFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP025565.1|WP_003740435.1|532031_532337_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP025565.1|WP_020830750.1|532412_532679_+|transposase
MARIEYGEEIQKSLLVLYSRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQVRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP025565.1|WP_003734772.1|533414_534032_+|hypothetical-protein
MLMSLSVLPLATYASETENTPTESYDGENFIATQTGNTLVIEDKKTGETVKIEMNDEENGVITSDDGTIENVHRDEEGNVYVDNELELEAPPLDIEDGINIATQPRLLKASKWIYVQTTKYNTTTQGNMRSLALGILSFMPITGPIFGIVAIIDAARSMGAKTLYVRVKQYRTSGYQFYKYDSYYYANASLTKLVKKTSQTKRMW
>NZ_CP025565.1|WP_003734773.1|534341_534689_+|hypothetical-protein
MQKDTYSGIRLSVIQLIDSKKENLKENNIKLTIIKDEKDGYVVELDNDKCMAEIVVEEPTYAPYRYISFEVVSLMDGKVKIIYSWYDDETSQWSDIEKELNKGIQFLNNFKTMEQ
>NZ_CP025565.1|WP_003734774.1|535092_535335_+|hypothetical-protein
MKRIILTSTLIVWTIVCIYMSISMVSNNTGIAFPIWLHIILLICFLATGIVNVKKKEYLWSTMLFEGVLVVLLSLIIVLV
>NZ_CP025565.1|WP_003734775.1|535417_536395_-|HD-domain-containing-protein
MKITDPLYGTFEIEPVLAELIQSPLVSRLAYVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFDDISKWKILEQEAPELCADRIDYTLQDLYRHRKISLAEVEEFLQALVMVDGRLYLANIALAEWFVAQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITTADLRLTDTELLAKLNANSDAREKIQLLASAHLEENEADFTYHHKKKMRLINPSILVDGRLIPADELSEKVRKMNDWASERSKHGIYIKATKKSKQ
>NZ_CP025565.1|WP_012681110.1|537156_537984_+|hypothetical-protein
MKKRLIGIITALLLVSGILLSPQMAQAETKVDYDALYQQGVSEGIINKADVSLETWIKENESEYNQVYQDGLKDGVYDASLSYEEWIKLNNYGQPPVVDENWEEVPQKPMLKGVYKGYNIKKGDILITNGTSSSGLLGHAAIANGNEYILDIPGAGKTTRQVPTSKWMSDYDPEGWVKVYRLKDSSVANAAANWADKNYYSTKGTSKQNIFPKYGMTGSRYSKNPTYCSKIVLQAYYFGTGNKPVVQVFPSLVTVYDLPNYFSKAYKPQQVKYFK

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Crispr_ID: NZ_CP025565_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025565_3

529548-530132

Orphan

Consensus_repeat	Method
GATGTAAGTAATTTTGATACNAGTTCAGTAACTNATATG	CRT

7 spacers

The CRISPR arrays of NZ_CP025565_3

>merge|NZ_CP025565|3|529548-530132|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATGTGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTGGATGTAAGTCATTTTGATACGAGTTCAGTAACTAATATGTCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTGGATGTAAGCAACCTTGATACGAGTTCAGTAACTAATATGTATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATGTATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTAGATGTAAGTAATTTCGATACCAGTTCCGCTACTGAAATGGTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTGGATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATGCGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTAGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGGCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

>NZ_CP025565|3|1|529548-530132|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATG	TGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTG
GATGTAAGTCATTTTGATACGAGTTCAGTAACTAATATG	TCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTG
GATGTAAGCAACCTTGATACGAGTTCAGTAACTAATATG	TATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATG	TATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTA
GATGTAAGTAATTTCGATACCAGTTCCGCTACTGAAATG	GTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTG
GATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATG	CGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTA
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	GCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTT
GATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025565.1\|WP_012681110.1\|537156_537984_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573
NZ_CP025565.1\|WP_014929030.1\|526907_528755_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP025565.1\|WP_003740435.1\|532031_532337_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP025565.1\|WP_003734774.1\|535092_535335_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003725189.1\|520544_521828_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP025565.1\|WP_020830750.1\|532412_532679_+\|transposase	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734775.1\|535417_536395_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP025565.1\|WP_003728093.1\|521828_522929_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP025565.1\|WP_003721252.1\|531025_531499_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734772.1\|533414_534032_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734773.1\|534341_534689_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025565.1\|WP_003734632.1\|513530_514286_-\|DUF4866-domain-containing-protein	unknown	unknown	gnl\|CDD\|379782
NZ_CP025565.1\|WP_014929029.1\|525105_526644_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP025565.1\|WP_003721242.1\|517711_518659_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP025565.1\|WP_107681183.1\|522921_524472_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP025565.1\|WP_003740428.1\|518814_520410_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP025565.1\|WP_003734634.1\|516558_517707_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP025565.1\|WP_003727314.1\|538011_538371_+\|DUF3139-domain-containing-protein	unknown	unknown	gnl\|CDD\|371476
NZ_CP025565.1\|WP_003734633.1\|514402_516562_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP025565.1\|WP_010958986.1\|531518_532004_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025565.1\|WP_012681110.1\|537156_537984_+\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	0.00019582
NZ_CP025565.1\|WP_014929030.1\|526907_528755_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	8.47304e-32
NZ_CP025565.1\|WP_003740435.1\|532031_532337_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.51255e-05
NZ_CP025565.1\|WP_003725189.1\|520544_521828_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP025565.1\|WP_003734775.1\|535417_536395_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	3.2717e-43
NZ_CP025565.1\|WP_003728093.1\|521828_522929_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP025565.1\|WP_003734632.1\|513530_514286_-\|DUF4866-domain-containing-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
NZ_CP025565.1\|WP_014929029.1\|525105_526644_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	9.23286e-20
NZ_CP025565.1\|WP_003721242.1\|517711_518659_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP025565.1\|WP_107681183.1\|522921_524472_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	4.3062e-106
NZ_CP025565.1\|WP_003740428.1\|518814_520410_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP025565.1\|WP_003734634.1\|516558_517707_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.03616e-53
NZ_CP025565.1\|WP_003727314.1\|538011_538371_+\|DUF3139-domain-containing-protein	gnl\|CDD\|371476	pfam11337, DUF3139, Protein of unknown function (DUF3139). This family of proteins with unknown function appears to be restricted to Firmicutes.	1.02958e-22
NZ_CP025565.1\|WP_003734633.1\|514402_516562_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.58381e-28

>NZ_CP025565.1|WP_014929030.1|526907_528755_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSDVITEGVPQEKPAEAENLEEIPTTDELMQNPNVLERSVADSDDSDLTVVSSGAYWTLYYNSANGEYSLRMFGNVPSSRPTAWNNYLKRIKHIEIEEATLTGDFVGYFGWFIGLKGVRIEGSDLSGVTSFQQAFSNSSLEKVIIKNNYYSNSQSLTNTKQMFFMAKNLSELDLSGLNTSFVTTMERMFEGCENLKILNLSNFDFDTSSVINMDYMFADCTNLEELDVSKFDTSSVTFMQMMFQYCKSLEKLNLSSFDTSSVTRMNSMFEGCTSFEELDLSSFDTSSVGNMQTMFQGCTNLKVLYLDKFDDNITTNKNNMFGNTPLLSYLRFSHRFTKLENIGLENTNWYDEKNWVQFSNITQLQTYNKQQSEPTGYRKGAFFSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEASELKVEGINRGGKTLSVGLNYGKTTISESNKLTLSNTADTTVQCLAPLSWDGSETNPKNAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSVNYE
>NZ_CP025565.1|WP_014929029.1|525105_526644_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLSSFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNNNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLTSDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEILNQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>NZ_CP025565.1|WP_107681183.1|522921_524472_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDLELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP025565.1|WP_003728093.1|521828_522929_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP025565.1|WP_003725189.1|520544_521828_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP025565.1|WP_003740428.1|518814_520410_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP025565.1|WP_003721242.1|517711_518659_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP025565.1|WP_003734634.1|516558_517707_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLVDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP025565.1|WP_003734633.1|514402_516562_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVALLALVIIFRRRIRSYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFGTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP025565.1|WP_003734632.1|513530_514286_-|DUF4866-domain-containing-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NZ_CP025565.1|WP_003721252.1|531025_531499_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP025565.1|WP_010958986.1|531518_532004_+|hypothetical-protein
MNKLVLSTLSVAAMGMVIFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP025565.1|WP_003740435.1|532031_532337_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP025565.1|WP_020830750.1|532412_532679_+|transposase
MARIEYGEEIQKSLLVLYSRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQVRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP025565.1|WP_003734772.1|533414_534032_+|hypothetical-protein
MLMSLSVLPLATYASETENTPTESYDGENFIATQTGNTLVIEDKKTGETVKIEMNDEENGVITSDDGTIENVHRDEEGNVYVDNELELEAPPLDIEDGINIATQPRLLKASKWIYVQTTKYNTTTQGNMRSLALGILSFMPITGPIFGIVAIIDAARSMGAKTLYVRVKQYRTSGYQFYKYDSYYYANASLTKLVKKTSQTKRMW
>NZ_CP025565.1|WP_003734773.1|534341_534689_+|hypothetical-protein
MQKDTYSGIRLSVIQLIDSKKENLKENNIKLTIIKDEKDGYVVELDNDKCMAEIVVEEPTYAPYRYISFEVVSLMDGKVKIIYSWYDDETSQWSDIEKELNKGIQFLNNFKTMEQ
>NZ_CP025565.1|WP_003734774.1|535092_535335_+|hypothetical-protein
MKRIILTSTLIVWTIVCIYMSISMVSNNTGIAFPIWLHIILLICFLATGIVNVKKKEYLWSTMLFEGVLVVLLSLIIVLV
>NZ_CP025565.1|WP_003734775.1|535417_536395_-|HD-domain-containing-protein
MKITDPLYGTFEIEPVLAELIQSPLVSRLAYVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFDDISKWKILEQEAPELCADRIDYTLQDLYRHRKISLAEVEEFLQALVMVDGRLYLANIALAEWFVAQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITTADLRLTDTELLAKLNANSDAREKIQLLASAHLEENEADFTYHHKKKMRLINPSILVDGRLIPADELSEKVRKMNDWASERSKHGIYIKATKKSKQ
>NZ_CP025565.1|WP_012681110.1|537156_537984_+|hypothetical-protein
MKKRLIGIITALLLVSGILLSPQMAQAETKVDYDALYQQGVSEGIINKADVSLETWIKENESEYNQVYQDGLKDGVYDASLSYEEWIKLNNYGQPPVVDENWEEVPQKPMLKGVYKGYNIKKGDILITNGTSSSGLLGHAAIANGNEYILDIPGAGKTTRQVPTSKWMSDYDPEGWVKVYRLKDSSVANAAANWADKNYYSTKGTSKQNIFPKYGMTGSRYSKNPTYCSKIVLQAYYFGTGNKPVVQVFPSLVTVYDLPNYFSKAYKPQQVKYFK
>NZ_CP025565.1|WP_003727314.1|538011_538371_+|DUF3139-domain-containing-protein
MKKYKKWWITIGLVLIICIIGYIYWFAIPKHTANEAVDDYLAAQKINSTQVKTRDIQKDWTRGGYYVTIVFKDDPNLVYEYNYNSKRNTPYHINLLVFKDGSSQEDDQVKHPPLQEQKD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

130449 : 136976

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003728215.1\|130449_130902_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003721740.1\|130907_131243_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003724946.1\|131459_131888_+	hypothetical protein	NA	NA	NA	NA
WP_003728213.1\|131899_132316_+	hypothetical protein	A8ASQ1	Listeria_phage	3.2e-19	37.9
WP_003728212.1\|132595_132985_+	DUF5072 domain-containing protein	NA	NA	NA	NA
WP_003721744.1\|132997_133510_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003721745.1\|133557_133860_+	hypothetical protein	NA	NA	NA	NA
WP_003740367.1\|133901_134306_+	hypothetical protein	NA	NA	NA	NA
WP_003731178.1\|134292_136161_+	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_003734720.1\|136157_136976_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0

DBSCAN-SWA_2

1265325 : 1300831

Streptococcus_phage(30.0%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003735019.1\|1265325_1266723_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-118	50.0
WP_003726046.1\|1266845_1267106_-	hypothetical protein	NA	NA	NA	NA
WP_003726047.1\|1267229_1268642_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.9e-51	32.0
WP_003726048.1\|1268666_1268930_+	DUF3116 domain-containing protein	NA	NA	NA	NA
WP_003726049.1\|1269097_1269574_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_003726050.1\|1269611_1269857_-	hypothetical protein	NA	NA	NA	NA
WP_003726051.1\|1269853_1271059_-	MFS transporter	NA	NA	NA	NA
WP_003726052.1\|1271263_1271923_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003726053.1\|1271962_1272157_-	hypothetical protein	NA	NA	NA	NA
WP_003726054.1\|1272223_1273072_-	YitT family protein	NA	NA	NA	NA
WP_003726055.1\|1273690_1274404_+	trehalose operon repressor	NA	NA	NA	NA
WP_003726056.1\|1274434_1276081_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_003727531.1\|1276099_1277584_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_003726723.1\|1277701_1278163_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003726717.1\|1278201_1278666_-	hypothetical protein	NA	NA	NA	NA
WP_003734526.1\|1278854_1279769_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003734525.1\|1279794_1281042_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.7e-106	52.0
WP_003734524.1\|1281025_1281856_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	3.6e-46	42.4
WP_003734523.1\|1282002_1283142_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003723563.1\|1283221_1283617_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|1283767_1283983_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003727523.1\|1284106_1284640_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003731300.1\|1284655_1285321_+	hypothetical protein	NA	NA	NA	NA
WP_003727521.1\|1285582_1286521_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|1286635_1287919_+	trigger factor	NA	NA	NA	NA
WP_003723886.1\|1288103_1289363_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_069002568.1\|1289481_1290048_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_003726394.1\|1290082_1290652_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003727520.1\|1290753_1291296_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003726396.1\|1291305_1292169_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003727519.1\|1292165_1292951_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
WP_003727518.1\|1293084_1293945_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003727517.1\|1294217_1296296_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	5.4e-107	37.5
WP_003727516.1\|1296358_1297663_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003731303.1\|1297945_1298848_+	tyrosine recombinase XerC	A0A142K7N4	Mycobacterium_phage	1.8e-14	29.5
WP_003724001.1\|1298868_1299408_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003727514.1\|1299421_1300831_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	7.5e-44	27.8

DBSCAN-SWA_3

1831811 : 1840097

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726209.1\|1831811_1832378_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.3e-26	36.4
WP_003726210.1\|1832374_1833424_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
WP_003722245.1\|1833442_1834870_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_069002589.1\|1834854_1837074_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	6.5e-159	40.8
WP_003734638.1\|1837066_1837750_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1837753_1837999_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003734637.1\|1838010_1838724_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	6.7e-41	38.3
WP_003726215.1\|1838804_1840097_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_4

2406079 : 2448884

Listeria_phage(93.55%)

coat,portal,capsid,terminase,tail,plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003725136.1\|2406079_2406313_-	hypothetical protein	A8ATC5	Listeria_phage	1.2e-34	92.2
WP_003734985.1\|2406545_2406938_-	hypothetical protein	A8ATC1	Listeria_phage	5.1e-67	100.0
WP_015987299.1\|2406934_2407438_-	DUF4065 domain-containing protein	A8ATC0	Listeria_phage	7.0e-93	100.0
WP_003734987.1\|2407840_2408767_-	N-acetylmuramoyl-L-alanine amidase family protein	R4ICC5	Listeria_phage	9.9e-170	92.2
WP_031644824.1\|2408768_2409002_-	hypothetical protein	R4IBI3	Listeria_phage	1.7e-33	92.2
WP_031644822.1\|2408998_2409283_-\|holin	holin	R4IDW2	Listeria_phage	5.7e-44	98.9
WP_003725053.1\|2409295_2409661_-	hypothetical protein	A8ASL3	Listeria_phage	1.3e-11	100.0
WP_096811323.1\|2409697_2409856_-	hypothetical protein	Q9T1A1	Listeria_phage	7.1e-12	76.9
WP_050897660.1\|2409860_2410139_-	hypothetical protein	A8ATB3	Listeria_phage	2.9e-16	55.7
WP_107681204.1\|2410135_2411212_-\|plate	phage baseplate upper protein	Q9T1A3	Listeria_phage	6.9e-90	75.5
WP_107681205.1\|2411208_2412243_-	hypothetical protein	Q9T1A4	Listeria_phage	3.1e-148	77.6
WP_107681206.1\|2412243_2413269_-	hypothetical protein	Q9T1A5	Listeria_phage	6.4e-186	90.6
WP_107681207.1\|2413277_2414096_-\|tail	phage tail family protein	Q9T1A6	Listeria_phage	9.8e-145	90.8
WP_107681208.1\|2414097_2419461_-	tape measure protein	A8ASK6	Listeria_phage	0.0e+00	90.7
WP_010990224.1\|2419471_2420074_-	hypothetical protein	A8ASK5	Listeria_phage	3.7e-109	100.0
WP_003769943.1\|2420079_2420502_-	hypothetical protein	Q9T1A9	Listeria_phage	5.9e-69	97.9
WP_045552940.1\|2420554_2420887_-	Ig-like virion protein	Q9T1B0	Listeria_phage	1.5e-30	70.9
WP_107681209.1\|2420816_2421251_-\|tail	phage tail protein	Q9T1B1	Listeria_phage	3.0e-76	97.2
WP_003737937.1\|2421253_2421661_-	hypothetical protein	A8ASK1	Listeria_phage	2.0e-66	99.3
WP_029508830.1\|2421660_2421999_-	hypothetical protein	A0A0B5CTV8	Listeria_phage	5.4e-57	95.5
WP_107681210.1\|2421998_2422361_-\|capsid	minor capsid protein	A8ASJ9	Listeria_phage	2.1e-59	93.3
WP_107681211.1\|2422360_2422756_-	hypothetical protein	A0A059T5E3	Listeria_phage	1.1e-64	96.2
WP_107681212.1\|2422774_2423776_-\|coat	coat protein	A0A059T6D4	Listeria_phage	6.3e-186	99.4
WP_003734944.1\|2423775_2424366_-	scaffold protein	A0A059T7N8	Listeria_phage	2.5e-86	100.0
WP_107681213.1\|2424444_2425584_-\|capsid	minor capsid protein	A0A059T7W2	Listeria_phage	6.6e-208	99.7
WP_107681214.1\|2425589_2427080_-\|portal	phage portal protein	A0A0B5D0F2	Listeria_phage	2.4e-282	99.0
WP_107681215.1\|2427092_2428424_-\|terminase	PBSX family phage terminase large subunit	A8ASJ2	Listeria_phage	4.3e-259	98.2
WP_107681216.1\|2428392_2428935_-\|terminase	terminase small subunit	A8ASJ1	Listeria_phage	7.8e-90	97.2
WP_031670222.1\|2428974_2429274_-	hypothetical protein	A0A2H4JBC0	uncultured_Caudovirales_phage	3.8e-14	40.7
WP_003743388.1\|2429838_2430273_-	hypothetical protein	A8ASQ1	Listeria_phage	9.6e-75	98.6
WP_003727776.1\|2430291_2430456_-	hypothetical protein	A8ASQ0	Listeria_phage	2.5e-20	92.6
WP_107681217.1\|2430584_2430968_-	DUF2481 domain-containing protein	A8ASP8	Listeria_phage	7.4e-63	96.1
WP_031541233.1\|2430971_2431376_-	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	5.4e-64	94.0
WP_107681218.1\|2431320_2431512_-	hypothetical protein	A8ASP6	Listeria_phage	2.6e-24	93.7
WP_003743379.1\|2431530_2432013_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	2.4e-74	90.0
WP_003743377.1\|2432012_2432414_-	hypothetical protein	A8ATZ6	Listeria_phage	1.3e-54	83.5
WP_003743375.1\|2432424_2432652_-	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	1.9e-34	96.0
WP_003743374.1\|2432652_2432838_-	hypothetical protein	NA	NA	NA	NA
WP_003735013.1\|2432837_2433128_-	hypothetical protein	Q8W5X0	Listeria_phage	5.0e-43	90.6
WP_003735014.1\|2433124_2433310_-	hypothetical protein	A0A059T5G1	Listeria_phage	1.2e-26	98.4
WP_003735015.1\|2433306_2433576_-	hypothetical protein	A0A059T7S7	Listeria_phage	5.8e-38	89.5
WP_003743371.1\|2433588_2434290_-	hypothetical protein	NA	NA	NA	NA
WP_003743369.1\|2434289_2434793_-	hypothetical protein	A0A0B5CYR4	Listeria_phage	9.3e-29	44.8
WP_003735032.1\|2434971_2435151_-	hypothetical protein	A0A059T5G0	Listeria_phage	3.5e-23	93.2
WP_107681219.1\|2435147_2435777_-	DUF1642 domain-containing protein	A8ATY9	Listeria_phage	7.0e-50	53.1
WP_023546290.1\|2435779_2436010_-	hypothetical protein	A0A059T7Z5	Listeria_phage	3.8e-38	96.1
WP_107681220.1\|2436006_2437269_-	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	2.5e-123	55.5
WP_045553719.1\|2437265_2438180_-	DnaD domain-containing protein	A0A0B5D175	Listeria_phage	5.2e-139	89.2
WP_045553720.1\|2438199_2439015_-	recombinase RecT	A8ATY6	Listeria_phage	1.0e-149	98.5
WP_010990195.1\|2439014_2439974_-	YqaJ viral recombinase family protein	A8ATY5	Listeria_phage	8.1e-175	98.1
WP_003734954.1\|2440206_2440395_-	hypothetical protein	A0A0B5CU43	Listeria_phage	4.5e-29	100.0
WP_003727752.1\|2440503_2440719_-	hypothetical protein	Q9T176	Listeria_phage	1.8e-26	90.1
WP_003735000.1\|2440715_2441249_-	hypothetical protein	A8ATY1	Listeria_phage	1.8e-78	87.9
WP_069007990.1\|2441371_2442148_-	antirepressor	A0A0B5D0I2	Listeria_phage	2.7e-136	95.3
WP_003731223.1\|2442211_2442754_+	hypothetical protein	A8ATX9	Listeria_phage	2.8e-95	100.0
WP_107681221.1\|2442731_2443085_-	hypothetical protein	A8ATX8	Listeria_phage	1.8e-50	93.2
WP_107681222.1\|2443081_2443318_-	hypothetical protein	A0A059T5E9	Listeria_phage	4.8e-36	97.4
WP_014931716.1\|2443382_2443742_+	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	2.1e-06	26.3
WP_107681223.1\|2443700_2443895_-	hypothetical protein	A0A059T6E5	Listeria_phage	4.1e-25	95.3
WP_107681224.1\|2444118_2444385_-	hypothetical protein	A0A059T7Q1	Listeria_phage	4.7e-40	97.7
WP_003759640.1\|2444403_2444688_-	hypothetical protein	A0A0B5D168	Listeria_phage	8.0e-38	83.0
WP_107681225.1\|2444707_2444908_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_107681226.1\|2445079_2445565_+	helix-turn-helix transcriptional regulator	A8ASM2	Listeria_phage	8.0e-38	61.2
WP_107681227.1\|2445721_2445889_+	hypothetical protein	NA	NA	NA	NA
WP_107681228.1\|2445943_2446594_+	hypothetical protein	NA	NA	NA	NA
WP_107681229.1\|2446656_2448015_+	recombinase family protein	Q9T193	Listeria_phage	3.6e-253	97.6
WP_003734805.1\|2448005_2448482_+	competence protein ComK	NA	NA	NA	NA
WP_003739618.1\|2448536_2448884_-	helix-turn-helix transcriptional regulator	A0A0A7RTK4	Clostridium_phage	9.9e-06	40.7

DBSCAN-SWA_5

2606022 : 2613867

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003725407.1\|2606022_2606994_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_003734495.1\|2607001_2607970_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-68	43.6
WP_003722606.1\|2607971_2608847_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_107681231.1\|2608954_2610685_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	7.3e-174	53.3
WP_003741152.1\|2610726_2611788_-	galactose mutarotase	NA	NA	NA	NA
WP_003725411.1\|2611804_2612788_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.0e-52	38.1
WP_003722610.1\|2612907_2613867_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP025565

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection