CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP028160	Lactococcus lactis subsp. lactis strain 14B4 chromosome, complete genome	2 crisprs	cas3,DEDDh,csa3,DinG	0	0	9	0
NZ_CP028161	Lactococcus lactis subsp. lactis strain 14B4 plasmid p14B4, complete sequence	1 crisprs	NA	0	2	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP028160_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028160_1

1475785-1475883

Orphan

Consensus_repeat	Method
CTATGGATAAAATGCTCGCTTTGGTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP028160_1

>merge|NZ_CP028160|1|1475785-1475883|CRISPRCasFinder
CTATGGATAAAATGCTCGCTTTGGTCGCTAACGAACGAGAGAATTATCAGTTCCACTGACAATTCTTTTAACTATCGATAAAATGCTCGCTTTGGTCGC

>NZ_CP028160|1|1|1475785-1475883|CRISPRCasFinder
CTATGGATAAAATGCTCGCTTTGGTCGC	TAACGAACGAGAGAATTATCAGTTCCACTGACAATTCTTTTAA
CTATCGATAAAATGCTCGCTTTGGTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028160.1\|WP_003131089.1\|1472329_1472860_+\|heptaprenyl-diphosphate-synthase-subunit-I	unknown	unknown	gnl\|CDD\|227110
NZ_CP028160.1\|WP_109991018.1\|1485382_1486195_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP028160.1\|WP_109991017.1\|1484141_1485305_-\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP028160.1\|WP_017864591.1\|1475004_1475718_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NZ_CP028160.1\|WP_124137356.1\|1474538_1474718_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028160.1\|WP_025017118.1\|1483266_1483803_-\|rRNA-large-subunit-pseudouridine-synthase-E	unknown	unknown	gnl\|CDD\|211334
NZ_CP028160.1\|WP_003131090.1\|1472850_1473810_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP028160.1\|WP_012897960.1\|1471925_1472333_+\|NusG-domain-II-containing-protein	unknown	unknown	gnl\|CDD\|227646
NZ_CP028160.1\|WP_003131084.1\|1467704_1468883_-\|toxic-anion-resistance-protein	unknown	unknown	gnl\|CDD\|377557
NZ_CP028160.1\|WP_109991016.1\|1479944_1481156_+\|virion-core-protein	unknown	unknown	gnl\|CDD\|226711
NZ_CP028160.1\|WP_010905895.1\|1469027_1469654_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227252
NZ_CP028160.1\|WP_023164251.1\|1481315_1482455_+\|ATP/GTP-binding-protein	unknown	unknown	gnl\|CDD\|369254
NZ_CP028160.1\|WP_003131091.1\|1473806_1474523_+\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|223434
NZ_CP028160.1\|WP_017864604.1\|1482451_1483237_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP028160.1\|WP_109991019.1\|1486169_1486514_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028160.1\|WP_015426578.1\|1470913_1471855_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP028160.1\|WP_058204146.1\|1476946_1477735_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|99814
NZ_CP028160.1\|WP_003131086.1\|1469845_1470871_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NZ_CP028160.1\|WP_029344009.1\|1478203_1479568_-\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|341046
NZ_CP028160.1\|WP_103054834.1\|1475938_1476874_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982

Protein	Function_ID	Function_description	E-value
NZ_CP028160.1\|WP_003131089.1\|1472329_1472860_+\|heptaprenyl-diphosphate-synthase-subunit-I	gnl\|CDD\|227110	COG4769, COG4769, Predicted membrane protein [Function unknown].	1.74231e-64
NZ_CP028160.1\|WP_012897960.1\|1471925_1472333_+\|NusG-domain-II-containing-protein	gnl\|CDD\|227646	COG5341, COG5341, Uncharacterized protein conserved in bacteria [Function unknown].	7.84966e-52
NZ_CP028160.1\|WP_017864591.1\|1475004_1475718_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	4.01899e-133
NZ_CP028160.1\|WP_025017118.1\|1483266_1483803_-\|rRNA-large-subunit-pseudouridine-synthase-E	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	1.60736e-99
NZ_CP028160.1\|WP_003131090.1\|1472850_1473810_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	9.30264e-84
NZ_CP028160.1\|WP_058204146.1\|1476946_1477735_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|99814	cd06218, DHOD_e_trans, FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+. In L. lactis, DHOD B (encoded by pyrDa) is co-expressed with pyrK and both gene products are required for full activity, as well as 3 cofactors: FMN, FAD, and an [2Fe-2S] cluster.	1.32372e-108
NZ_CP028160.1\|WP_003131084.1\|1467704_1468883_-\|toxic-anion-resistance-protein	gnl\|CDD\|377557	pfam05816, TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.	2.06226e-124
NZ_CP028160.1\|WP_109991016.1\|1479944_1481156_+\|virion-core-protein	gnl\|CDD\|226711	COG4260, COG4260, Membrane protease subunit, stomatin/prohibitin family [Amino acid transport and metabolism].	1.09739e-168
NZ_CP028160.1\|WP_010905895.1\|1469027_1469654_-\|hypothetical-protein	gnl\|CDD\|227252	COG4915, XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein [General function prediction only].	2.19745e-89
NZ_CP028160.1\|WP_023164251.1\|1481315_1482455_+\|ATP/GTP-binding-protein	gnl\|CDD\|369254	pfam07191, zinc-ribbons_6, zinc-ribbons. This family consists of several short, hypothetical bacterial proteins of around 70 residues in length. Members of this family have 8 highly conserved cysteine residues, which form two zinc ribbon domains.	0.000852226
NZ_CP028160.1\|WP_003131091.1\|1473806_1474523_+\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|223434	COG0357, GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane].	2.20408e-85
NZ_CP028160.1\|WP_017864604.1\|1482451_1483237_+\|hypothetical-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.16841e-69
NZ_CP028160.1\|WP_015426578.1\|1470913_1471855_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	5.53483e-173
NZ_CP028160.1\|WP_109991018.1\|1485382_1486195_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.47704e-28
NZ_CP028160.1\|WP_109991017.1\|1484141_1485305_-\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	4.78809e-46
NZ_CP028160.1\|WP_003131086.1\|1469845_1470871_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	1.94654e-180
NZ_CP028160.1\|WP_029344009.1\|1478203_1479568_-\|multidrug-efflux-MFS-transporter	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.48693e-66
NZ_CP028160.1\|WP_103054834.1\|1475938_1476874_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	0

>NZ_CP028160.1|WP_017864591.1|1475004_1475718_-|orotidine-5'-phosphate-decarboxylase
MQENRPVIALDFPEFSDVKDFLEKFDPSEQLYIKLGMELFYTAGPQVVYYVKSLGHSVFLDLKLHDIPNTVESSMRVLARLGVDMVNVHAAGGVEMMVAAKRGLVAGTPVGRQRPKLIAVTQLTSTSEKIMQNDQKIMTSLEESVINYAQKTAQAGLDGVVCSAHEVEKIKAATSKEFICLTPGIRPEGASKGDQKRVMTPKEARTIGSDYIVVGRPITQAKDPVASYHAIKAEWNQ
>NZ_CP028160.1|WP_124137356.1|1474538_1474718_-|hypothetical-protein
MWKNKFTKFWFRYRSIHITFILLSIFTSLSLTAPAMVMNSFTAIVSISVLVINLSKKIG
>NZ_CP028160.1|WP_003131091.1|1473806_1474523_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTPDEFLSALTEFDIQLSDKQIKQFERYFELLVEWNEKINLTAITEKNEVYLKHFYDSIAPILYGLITDQPVSILDIGAGAGFPSLPMKIIFPELKVTIIDSLNKRINFLSLLTEELGLENVTLLHGRAEDFGQDANYRGTFDFVTARAVARLSVLTEFTIPFLKKNGILLSLKAAQFEEELNDAKKAIATLGGKFIKEVAYELPNGDERHIALIEKKKETPKKYPRKAGTPAKNPIK
>NZ_CP028160.1|WP_003131090.1|1472850_1473810_+|polyprenyl-synthetase-family-protein
MDLKNNFWKDYPELEKELVQVQQLMKSHVTIKNSDVKSAIFDIFDAGGKMLRPAYLLLFSGFTDLSESERLALAASVEMMHTATLVHDDVIDHADTRRGVATLSAKYGPEIAVYAGDYLFIAVFRLMSEHSLELSNLTKNIGSIERLLGGELGQLNHHFNLQQTLDDYIENISGKTGELFALSASVAPLISKNNTLTKRAYKIGMNIGISFQIMDDYLDYASTAQTLGKPVLEDIKQGIYSAPVLFALQENNALVSELIKNEKFDEVYDFIKTSDALEKTKALAKSYTLSALNLIDKLPKGKNRELIAEITRKLLERTL
>NZ_CP028160.1|WP_003131089.1|1472329_1472860_+|heptaprenyl-diphosphate-synthase-subunit-I
MNIKEYVYVSLLTAAAVVMGIIESSLPPFFAFAPGAKVGLANLVMIIAVFTLRWRQVWVMQILRLLITALFTGFSVFLYSFAGGILSLLAMYLMKQFGPKLVSMIGISTVGGFFHNFGQLAMASLLAKTTSVMLYLPWLAFFGILAGFAIGIAGNQLITRVKPIQELFIKESKQWT
>NZ_CP028160.1|WP_012897960.1|1471925_1472333_+|NusG-domain-II-containing-protein
MNFFKNTVNFFKSIKTKPLDFVIIFLLFIASFSTLFFFATGSKGAQAELRISGKVIKTFDLNKNQTWTYRDKDGDYNKIQVKNGEIAVVEANCKDQIDVQRGYISKTGETIVCLPHNLVIEVMSGQKDEQVDYKV
>NZ_CP028160.1|WP_015426578.1|1470913_1471855_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKQNTIPTKARKVRKAVIPAAGLGTRFLPATKAIAKEMLPIVDKPTIQFIVEEALKSGIEDILIVTGKAKRPIEDHFDSNIELEQNLLEKGKTELLKLVEETTDINLHFIRQSHPKGLGHAVLQAKAFVGNEPFVVMLGDDLMNITGNETPLTKDLINDYEKTHASTIAVMKVPHDDVDKYGVIDPNGEVSKGLYNVERFVEKPNVDEAPSDLAIIGRYLLTPEIFDVLETQVPGAGNEIQLTDAIERLNKTQRVFAHEFTGKRYDVGDKLGFVETTIEYGLEHPQIGANLKNYIIEKAKELSKDDSKNITKK
>NZ_CP028160.1|WP_003131086.1|1469845_1470871_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEKIKAFDRLDLALEDVDAILFVVPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKDHDEAKYAQAIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLGIDMPITETIYKVLYENLDAKTGILDIMRRETRAENEFINNK
>NZ_CP028160.1|WP_010905895.1|1469027_1469654_-|hypothetical-protein
MPVSLFMNHQDMMFGYGHLGIVNVIFGLVLFFLIIKMIIGISFMRKNPDEREEGYKDKGMSKKENIERYHEAGLSDTDIKIFRENLSEAKENIKTWEKLLKKEDDLQVVESVTGGLEASKQTFKYIVQNPQELTKQNEFLYKDLPNMVKLSEKFIEMKKQSVRTEEINRDLDETLLLIKTLSHSISKNYHEILMDDVNVIKHQVDFDK
>NZ_CP028160.1|WP_003131084.1|1467704_1468883_-|toxic-anion-resistance-protein
MDNPILDDLMTNDKVIKEAEQLDEQQKSEIVKMHEKASLAAVEVLSTEELEKAKELSKQLDESSAQSVINYGASAQDKISAFSQSVLNKVQAQDLGEVGSSLTDLMFNLQQANPNELVAENKGIFTKMFGKVKRSIFEVTQKYQKIGAGIDKISAKLNNEQQGLLQDNEMLDKLYDENLNYFKALNVYIAGAELKVQELDTEIIPQARKEAQDSTDNALIVQKVNDLESYKNRLEKRAHDLRLARQLTIQQAPQIRLIQNTNQELAEKIQTSINTAIPLWKNQVAIALTLLKQKDALTSQRIVSETTNDLLRKNSEMLKASTIEAATENERGLVDIETLKLTQQNLVDTIQETMRIQAEGRQKRQQGEVELSKMEEEIKEKLLQLSNNKQLN
>NZ_CP028160.1|WP_103054834.1|1475938_1476874_-|dihydroorotate-dehydrogenase
MTENNRLSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPTPRVAETASGMLNAIGLQNPGLEVIMAEKLPWLNENFPDLPIIANVAGSEEDDYVAVCAKIGDAPNVKAIELNISCPNVKHGGQAFGTDPDVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEHACADGLTMINTLMGVRFDLKTRKPVLANITGGLSGPAIKPVALKLIHQVAQVVDIPIIGMGGVESAQDVLEMYMAGASAVAVGTANFADPFACPKIIEKLPEVMDQYGIDSLENLIQEVKNSKK
>NZ_CP028160.1|WP_058204146.1|1476946_1477735_-|dihydroorotate-dehydrogenase-electron-transfer-subunit
MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSWDKVAKTCTILYRIGDETSGTYEISKLQTGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAELKNVSLKIATDDGSYGTKGHVGMLMEEVDFEVDALYTCGAPAMLKAVAKKYDQLERLYISMESRMACGIGACYACVEHDKEDENHALKVCEDGPVFLGKQLSL
>NZ_CP028160.1|WP_029344009.1|1478203_1479568_-|multidrug-efflux-MFS-transporter
MNKNNHFHLLGAVIATGILSFSGVLIETAMNVTFPTLINEFGLSTSKIQWVTTIYLLVIAITIPLSSYFNERFSARKLFLVANLIFLVGVLTNCFSPNFAMLLFGRLLQGVGTGIGLPLMFHLILTKAPLHKRGMMMGIGTLTTSIAPAIGPTYGGIISNSLDWRYIYIFLLPLVVISLVLGLACLPREGAKTPKKLALRPVIALSIMFFAFISALSAEHLMTFALLFIVGLVGAFLFVQFNRKESLIDLGILKNHRFVALIFSLLVYQALLLGLSFVLPSFIQVSAGFSSSVAGLFMFPGALIGAVLAPISGKVLDQIGARKPITTGLILAALGLALLFVFLPTKSLALLLVAHIVLMLGLGISYSNLMTCSLSTLATDQLSDGNALVNTLQQFIGAVATAVVATTLSIFQGLNGFKVGTSHGTSIILALFFILIIVSLIVSFPNLKKIRANH
>NZ_CP028160.1|WP_109991016.1|1479944_1481156_+|virion-core-protein
MGIIKAATGSLGGALADQWLEVIEPNEMSDQTVFTKGIKVRKDAKRGSNRKGTEDVITDGSIVHVYENMMMILVDGGKIIDYTAEPGYYTVKNDTAPSLFNGDLRDSIQESFFRFKFGGTTPQKQEVYYVNLQEIKGIKFGTATPLQYFDNFYNAELFLRTHGTYSIKITDPLAFYANVIPKNADHVEIQEINDQYLAEFLTALNTSINQYSAQGERVSFLTSKSMELSKYMASVLDEDWKQLRGMEIVSVAVASISYTDDSQKLINMRNQGAMLGDPSIREGFVQGAVARGLEAAGSNTGGAPNAFMGMNMGGQNLAGFSQTNQSQMQAQAENKADTWTCPECNTKNTGKFCSNCGQAKPSATPVMPELNMACNECGAVVNLANGVPKFCPECGKPFVAKAL
>NZ_CP028160.1|WP_023164251.1|1481315_1482455_+|ATP/GTP-binding-protein
MSESQVLTHKCPNCGGPLLFEPKNQKFHCEYCGSTFTEQEVSDFEAKQEAAKVTDSPISSVSNAETTDEKEKITDSDQKRADENTDEEIGLFLCPSCGAEIVTDATTASTWCYYCHNPVVLTERLSGKFLPEKILPFQIERKAAEEQFLDWVGKKKFVPKAFFDKKQIQNLSGVYFPYWAVDAELSGGISAQATNLRVWIVGDTEYTEHSQYEIQRGGETKFKDLIKNALKKNLSDKMVGAVQPFDMTAAIPFKNQYLSGFLTEKRDIEFPDMKENVEREFRQYADGLMESTIVGYTSVSNLQSNQQIKNIDEDYVLLPIWLVTYKEAGNDRLFYYAMNGQTGKVAGLLPIDKKKLWTVAIGIFILVLLLGIIVGYLLS
>NZ_CP028160.1|WP_017864604.1|1482451_1483237_+|hypothetical-protein
MRKKLVILSLFFLSFFFLLLAPKTSAATFSSGLEDNLQLFGGNVTLLEQEAQKLANETKAGVYVVTTDSSTPASQMAKTYLADKVGAKNNGVVLVINMNLRKVYIWATGNLKYYLPSSRIEKTLDIVQPELTDNNYYQAVSGFFDQVSKYYQAGIPTSRKYSINSETGAVTFHRSFQPLSILIALIISLIAAGGFVWTIYRRYQMKDAHAVWRYDYGRNGNLELHQREDILVNTFITTRIIPRPSSDNNNFSDGSGGGRSF
>NZ_CP028160.1|WP_025017118.1|1483266_1483803_-|rRNA-large-subunit-pseudouridine-synthase-E
MIILFNKPYDVLTKFTDGEGRKTLKDYIKIPNVYAAGRLDKDSEGLLLLTDDGKLNHLLTDPKSKSYKTYLVQVEGEFSSEAAQKLQKGLLLKDGKTLPAKVKLIDEPDWLWERTPPIRERKAIPTSWVEISIKEGKNRQIRRMTAAVGFPTLRLIRWSIGQYSLGNLKSGEYKIIQK
>NZ_CP028160.1|WP_109991017.1|1484141_1485305_-|DUF916-and-DUF3324-domain-containing-protein
MKKLQLFLSAIFLTLSFGLAQTGYARTDDYTVKPIIPENQSNKDLGYFDILLGADKEQTLQVELSNNTEQEIKIDVTLSSAVTNMTGLVVYEPTEIVADSSLKYNLKDYVNTPKVVTLPPLTRQKLDLKVKMPNEAFDGQIAGGITFSKEGQNDKEEDSEGITVKNTYSYTIALLMRQNDNEVSPDLKLKTVSPSQINGRNVINVNLQNPTMTYINTMNVKATISGISNTDIKYTYSNSMMQMAPNTSFDLPIPTSNQSAATRVSEPLKPGKYRLQLVVNARTDDQGKYEAQVDNKTARYKYQWTFDQEFTISDNQAQKLNDSDPTVKKEKDWTWLLFVIGILLLVLFFIILLWKRRKKSQKEEEEKQALREKIEVQEKIIDDLNKK
>NZ_CP028160.1|WP_109991018.1|1485382_1486195_-|WxL-domain-containing-protein
MKKTILSLSGVAVITATLLSTSVLEVSATSVGSTTSGANVAFQPKKTPTNPVSPGDGKTPISPTTPGVPNTSNPVASDDGLTLDYVPAINFGTHYVDASTAHTWSAWAANDGSGKAIPQFMQVTDNRGTATGPTGWSVSLTQTAQFKGMKAGDLVNAVMTFNNDKTNTVVSTSMNKASSTVNTATNALVPGTAVNIFQADAGTGTGTNLLSFGAGDGSTLVTDPETLDSATNTTGKVDPNITLNVPAGSAKVDTYTTTLNWNLYSAPGNA
>NZ_CP028160.1|WP_109991019.1|1486169_1486514_-|hypothetical-protein
MKIKYILWVICALLLLNTSVILAQEIGGTNTTGKVGFLEKEPIEKPPVTSSSQATGQSQILTNQNLPIVGTNQNDSLLPFVVGLVTIGVGSLMIKKTKRIRIKENFYEKNNTQP

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Crispr_ID: NZ_CP028160_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028160_2

1936915-1937009

Orphan

Consensus_repeat	Method
TTTATTACTGACAGACTTGTCAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP028160_2

>merge|NZ_CP028160|2|1936915-1937009|CRISPRCasFinder
TTTATTACTGACAGACTTGTCAGCTTTGCTGACAAATCCTTCATCCATTGATAAAAAGCTCAATTCAATCGCTTTTTACTGACAGACTTGTCAGC

>NZ_CP028160|2|2|1936915-1937009|CRISPRCasFinder
TTTATTACTGACAGACTTGTCAGC	TTTGCTGACAAATCCTTCATCCATTGATAAAAAGCTCAATTCAATCG
CTTTTTACTGACAGACTTGTCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028160.1\|WP_033899919.1\|1945473_1946382_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_CP028160.1\|WP_109991140.1\|1927677_1927956_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028160.1\|WP_109991141.1\|1927967_1928417_-\|DUF4176-domain-containing-protein	unknown	unknown	gnl\|CDD\|226892
NZ_CP028160.1\|WP_021722251.1\|1941740_1943072_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
NZ_CP028160.1\|WP_109991142.1\|1928422_1932901_-\|type-VII-secretion-protein-EssC	unknown	unknown	gnl\|CDD\|274860
NZ_CP028160.1\|WP_010906139.1\|1937701_1938184_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP028160.1\|WP_004255197.1\|1937127_1937586_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NZ_CP028160.1\|WP_033899921.1\|1944639_1945326_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP028160.1\|WP_004255181.1\|1940795_1941566_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP028160.1\|WP_109991138.1\|1926043_1927327_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368093
NZ_CP028160.1\|WP_011835708.1\|1934856_1935147_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|227179
NZ_CP028160.1\|WP_058211683.1\|1934279_1934750_-\|type-VII-secretion-protein-EssA	unknown	unknown	unknown
NZ_CP028160.1\|WP_017864923.1\|1939402_1940659_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP028160.1\|WP_004255207.1\|1935481_1936894_-\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NZ_CP028160.1\|WP_109991145.1\|1943074_1943776_-\|adaptor-protein-MecA	unknown	unknown	gnl\|CDD\|227199
NZ_CP028160.1\|WP_109991144.1\|1938185_1939403_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP028160.1\|WP_004255171.1\|1943905_1944640_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP028160.1\|WP_058211682.1\|1934016_1934280_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378057
NZ_CP028160.1\|WP_109991143.1\|1932902_1934030_-\|type-VII-secretion-protein-EssB	unknown	unknown	gnl\|CDD\|188441
NZ_CP028160.1\|WP_109991139.1\|1927317_1927674_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP028160.1\|WP_033899919.1\|1945473_1946382_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.04246e-70
NZ_CP028160.1\|WP_010906139.1\|1937701_1938184_-\|hypothetical-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	3.28577e-22
NZ_CP028160.1\|WP_109991141.1\|1927967_1928417_-\|DUF4176-domain-containing-protein	gnl\|CDD\|226892	COG4495, COG4495, Uncharacterized protein conserved in bacteria [Function unknown].	0.000330962
NZ_CP028160.1\|WP_021722251.1\|1941740_1943072_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	2.04808e-85
NZ_CP028160.1\|WP_109991142.1\|1928422_1932901_-\|type-VII-secretion-protein-EssC	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP028160.1\|WP_004255197.1\|1937127_1937586_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	9.34852e-67
NZ_CP028160.1\|WP_033899921.1\|1944639_1945326_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	5.78444e-76
NZ_CP028160.1\|WP_004255181.1\|1940795_1941566_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.57723e-148
NZ_CP028160.1\|WP_017864923.1\|1939402_1940659_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	1.98344e-131
NZ_CP028160.1\|WP_011835708.1\|1934856_1935147_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|227179	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown].	1.95573e-21
NZ_CP028160.1\|WP_004255207.1\|1935481_1936894_-\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP028160.1\|WP_109991144.1\|1938185_1939403_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP028160.1\|WP_109991138.1\|1926043_1927327_-\|hypothetical-protein	gnl\|CDD\|368093	pfam04740, LXG, LXG domain of WXG superfamily. This domain is present is the N-terminal region of a group of polymorphic toxin proteins in bacteria. It is predicted to use Type VII secretion pathway to mediate export of bacterial toxins.	5.13733e-09
NZ_CP028160.1\|WP_004255171.1\|1943905_1944640_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.02808e-157
NZ_CP028160.1\|WP_058211682.1\|1934016_1934280_-\|hypothetical-protein	gnl\|CDD\|378057	pfam08817, YukD, WXG100 protein secretion system (Wss), protein YukD. The YukD protein family members participate in the formation of a translocon required for the secretion of WXG100 proteins (pfam06013) in monoderm bacteria, with the WXG100 protein secretion system (Wss). Like the cytoplasmic protein EsaC in Staphylococcus aureus, YukD was hypothesized to play a role of a chaperone. YukD adopts a ubiquitin-like fold. Usually, ubiquitin covalently binds to protein and flags them for protein degradation, however conjugation assays have indicated that the classical YukD lacks the capacity for covalent bond formation with other proteins. In contrast to the situation in firmicutes, YukD-like proteins in actinobacteria are often fused to a transporter involved in the ESAT-6/ESX/Wss secretion pathway. Members of the YukD family are also associated in gene neighborhoods with other enzymatic members of the ubiquitin signaling and degradation pathway such as the E1, E2 and E3 trienzyme complex that catalyze ubiquitin transfer to substrates, and the JAB family metallopeptidases that are involved in its release. This suggests that a subset of the YukD family in bacteria are conjugated and released from proteins as in the eukaryotic ubiquitin-mediated signaling and degradation pathway.	3.58752e-07
NZ_CP028160.1\|WP_109991143.1\|1932902_1934030_-\|type-VII-secretion-protein-EssB	gnl\|CDD\|188441	TIGR03926, T7_EssB, type VII secretion protein EssB. Members of this family are associated with type VII secretion of WXG100 family targets in the Firmicutes, but not in the Actinobacteria. This protein is designated YukC in Bacillus subtilis and EssB is Staphylococcus aureus. [Protein fate, Protein and peptide secretion and trafficking].	9.52354e-80
NZ_CP028160.1\|WP_109991145.1\|1943074_1943776_-\|adaptor-protein-MecA	gnl\|CDD\|227199	COG4862, MecA, Negative regulator of genetic competence, sporulation and motility [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion].	1.91709e-85

>NZ_CP028160.1|WP_004255207.1|1935481_1936894_-|Fe-S-cluster-assembly-protein-SufB
MTENSTQEVVKDLEEYKFGFHDNAELEFTTGLGLTEEVIREISETKNEPEWMLEFRLKSFEAFKKLDMPKWGPDLSGIDFNDIVYYQKPSAKAARSWEDVPQEIKDTFEKIGIPEAERSYLAGASAQYESEVVYHNMKDEFEKLGIIFTDTDSGLRDYPEIFKKYFSKLVPPTDNKLAALNSAVWSGGSFVYVPKGVKCEIPIQAYFRINNEKSGQFERTLIIVEEGASIQYVEGCTAPTYSASSLHAAVVEIFVEEGGYMRYSTIQNWSDNVYNLVTKRAAAEKNATVEWIDGNLGSKVSMKYPAVHLNGPGARGTMLSIAFAGANQNQDTGAKMIHNAPNTSSSIISKSIAKNGGAVNYRGQVTFGKNSKKSASHIECDTILMDDLSKSDTVPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLTEKEATDMIVMGFIEPFTKELPMEYAVELNRLISYSMEGSIG
>NZ_CP028160.1|WP_011835708.1|1934856_1935147_-|WXG100-family-type-VII-secretion-target
MGAISVTPAELKQQAQVYIQSKEQIEQAIQRVNSMNSTIAEEWKGQAFQAYLEQYNQLEQNVRKFEELLESINQQLNKYADTVEERDAQDAQSFGF
>NZ_CP028160.1|WP_058211683.1|1934279_1934750_-|type-VII-secretion-protein-EssA
MKKQKVFFIFSGLLFLFYSPFAVSADSDGSLQLNSDMITTQSGAGSSTSDFAIRSQLFSKDLDKKAQEKVKSGEEATKHIDEIDFNKESQNKLYKANYQSLKTELFKNYSQTNVASNDSKETSKNNGMLILLIMALPLMILTGVVARSLTRRKRRK
>NZ_CP028160.1|WP_058211682.1|1934016_1934280_-|hypothetical-protein
MKDHIEISLEWLGKQVDLAVPSNVTSTRLIELLAQAFKVNGQNLPEHWNFIVKGKSVALGSGLTLKELGLGNGDILQLIVGEKDEII
>NZ_CP028160.1|WP_109991143.1|1932902_1934030_-|type-VII-secretion-protein-EssB
MKLFDGQNTLTAERKDEQFIVYLTGTQVNQQELEFIKSKTNLVSSEDEEYAFKISYPLSNKEKSLKSLMLEMKSELERLELVLKLKTLSTKNSGYKVPFVHPENIFFIDGDLAFIHIGIRDGIAPMNIDDTLALSQYKALTLAILNPKISYDNFVNGEMSLRDKFSQALSNCDSFEEVLHLVETKLTKERQKEEAALVKVSKGRYRFFKYAGSVAVVAAIAMGVLTIIDQKTTIPKQKAIMTAQADFITSHYDKTLDDLKSYQPKQLSKDARFVLASSSINLANLSQTQKAAVLNNISSTTDDNTLNYWIYQGRGEFEKALNLAKNIGDDQLTLLAYTDLYQATKLNTSMNGDEKQKKLEEYNKQIQELSKSLGK
>NZ_CP028160.1|WP_109991142.1|1928422_1932901_-|type-VII-secretion-protein-EssC
MKELFELENSQNENQNFLYEVRHPEEILYVIFILKDQLERVTLTESQMTSAYENLMFGIVNDHVLVNGGRVSTGKNEIDGITFLVLAAQDLHTHFLVLDNQELVINNKNEHRAIQTLDDSLVIIDNEDENHPKALIKPLGDFAYYNNERLTQSGSREIKVGDTILTPDLMVERRSEQWKVTAFSQEIIFNPEFFLEQHRKLEKPQDFPEYRRSPRLNLEIPEEKFKYEKIEDKEQAPKGGLLKAVLPPVGMLAAGSITTLMSGRNPLMMMATALASLMTVTFTVTQYRTEKKDRLERESHREEDYQAYLAKTTSKIGQAHRQENEIIHYQQPSPQELLEMIEKYDSRLYERMVNNKDFLQVSLGTGTQPSGLKVETDYTSRDEDEWATHVKALVEKYSQQEDVPVALDLRNQTLGLIGNYDVLKNMISNLYLQMAFFQSYRDLNFITLVPEKSYAKDWQQWRFLPHFKVQGINTRGIVHNAKSRDIILSSFYQIINSRKQELNAAGREKPTFLPHFVFTIFDDSYLAGHGLNEFLAEDMSDLGVTVIWAKEDKKLLPETITALVEVKNQQAGVLIQDNGLHLDKVYKPYPQLESKENFEVVLRQMSSLEHMEVEKNAIPERLSLLEQYLVETVEDLNISERWAQAEPSKSIASMIGWKGKKEFAFWDLHEQVHGPHAIVGGTSGSGKSEFLTTFLMGLAINFSPEDIGMLIIDWKGGGIADTLADLPHFMGSITNLDGAGTARALASINAELKKRQREFREYGVSNIAGYTKLYRERNNPREGVNYPHKPLPHLMLVSDEFAELKENVPEFLDELTSVARIGRSLGVHLILATQKPDGVVNDQIDANAKSKVALKMSDEANSKALIKTGDAAHITNAGRGYLRVGESEVYELFQSGYGGVDYNPHATTEEIKDERIYRVNESGQWELLYDPREDLIDQGAVKEDLPTQLEATIDEIVKNFEHSSYTKPDKPWLPNLGEAIITTKPKAKKKRNLSIPLGLLDIPSMQEQKEYFYDLEKSSHTVIFASPGFGKSVTLQTTVMNLARQNTPEQVQFNLFDFGTNGLLPLKNLPHVADIVTLEENEKLQKMLHRLEQNLAERKALFKKEGVANLNQYQAKAKRELPILVNVLDSYDGLSQNDNRKDNIDNLLMKVLREGAAVGIYLVITAGRYNAIRMNMMANIQTKMALFLNEDGDLSNLFGRDKLEQVELPGRAQIKLDQPLALQIYLPVKGESEVEVLAALEQEITAMNNSWTGSLPDEIPMVPDELTPEAYAANINKEKDLMPLGLNKLSAQAEFFKLFNAKSLGIFPASAKQFKQVMPFLMEQLFESIENAEVILIDASKNMEQYASKASVYISKASIIEQNMNLQKAIQAWLSEESDTPRVLIMNGLADLVTQLNIQQAQLISLLTQNNPNKQLIVMDYFTRVGNSFNMPTTVVRENAYQILFGGDLNAQHFIETLSPETKKETFNKNVLHMVKDEEFFNVVIPMESEEV
>NZ_CP028160.1|WP_109991141.1|1927967_1928417_-|DUF4176-domain-containing-protein
MAQKDEKLQFLGLGSMVEIDHMDALADTLYTIVARAVGKDGDGKTILRYQVAPHPQGGSAKQADDIITLAESSITKVVHEGYHDEKDEVFLSKMITGMENAIKNMSSNPKKEKTVTLKKEPEKIEVPLPPKVEDEKELLKKDPFYKFRS
>NZ_CP028160.1|WP_109991140.1|1927677_1927956_-|hypothetical-protein
MAGKISSDLGSANAAVSQFKTGNSSSQHFSLGESNITGMKSAEKISNSIIGDLSKLESGIKKQADKFPKLAEIIEERDKQDAADLTTMNWGF
>NZ_CP028160.1|WP_109991139.1|1927317_1927674_-|hypothetical-protein
MTRDKNADKRLEFNRKIASKEQESDELHLEERKTQNRIENFEAVMMKSFRNLQAIEEELNRRSHIQAAYDETAQKQKYMSNVISQQKEGLKQVYQQRSLKLEDEREQLQKERDSLSWD
>NZ_CP028160.1|WP_109991138.1|1926043_1927327_-|hypothetical-protein
MGLIYNPTDSQGLVSALNANIRTADEMIESLNRASKHLIDALGNKTLSGAAFTAGKGMFSQLVIPTISKASQALDKLKSEAKQYEGFASNAGEELLDEDKLNEQLQNLQTQQAALSSQISFYNQLAASHSDDNALNTSYSDFSRQLSSFMGTTASDIQKIQDKLKKLHEFNTSVSPLFTTSDQDFKAILQGISLITSVTFTKDGKFSIDKIKDGYELLKGGLQYRDGKLFLGGEKIVETVNSNGEKVLKFGNKFLSKLENGHIYKNGKAFENLTKIDLANYKQFGKTFKSEFKTSINITEDFKAWKGATKFSKLGKALGGLGTVLTITDNATEDFKGGVNGESVKNFVVDTTVDVGSGAASTAAGAALGSLILPPLGTVVGAGLGVAFNFGLNYKYGNPPKSTVDHIKSGIKDGINKVGKLFSHKFW
>NZ_CP028160.1|WP_004255197.1|1937127_1937586_-|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSKLDNLYRAVILDHSSNPRHAGELQTGCMVDLNNPTCGDVIRLTVEFENDVISNIAFSGHGCTISTASASMMTVAVLGKTKEEAKELATIFSAMVTGETDERQEKLGDAQFLAGVSKFPARVKCSTLAWNALKKAIDVGEAQETVIHGE
>NZ_CP028160.1|WP_010906139.1|1937701_1938184_-|hypothetical-protein
MLNWVASLPLWLATTFLFVVVFFRAQCTFWLGKLSYHGILKTKWGKKLEKNSETSAGILAIQKMGWPIIPLSFLTVGFQTAVQFGAGLTNWSWYKYTLAAIPGYLAWGFIYASGGLSLFRSLVQGSIGLLILFIIIILAVVIAANLVLRYIRKNGIKTDD
>NZ_CP028160.1|WP_109991144.1|1938185_1939403_-|cysteine-desulfurase
MLEGIKKDFPVLNQIVNDEPLVYLDNAATTQKPLKVLAAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRQFINAKSTKEVLFTRGTTTSINWVAQFAGQILKTGDEIVISIMEHHSNIVPWQEVAKKTGVILKFVYLKDGQLDMDDLRKKITNQTKFVSIAHVSNVLGTINPVEEITKIAHEHGAYMVVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQFEPVEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEIELIDYLMPKLQEIEGLKIYGPKDNVKRGGLIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLETPATARASFYLYNTKADCDKLVEALKKTKEFFNLD
>NZ_CP028160.1|WP_017864923.1|1939402_1940659_-|Fe-S-cluster-assembly-protein-SufD
MNQEILNFSQMHAEPAWLSDLRQKAALEFENLELPNIERVKINRWGLDHLTISENEEIGSVPTFTEIPNHPLLVQVGSQTVMEQMTPNLAEQGVIFTDFNSALTEIPELLEENFGSVVPFNESRLTAANTATFNSGLVLYVPDGVEVLEPIESILMQEGSSEVPFNKRILIIVGKNAKVDYLERLETSGEQSSKVKANIVVEVIAKAGAQVKFAAIDRLGENVTASVVRRGLIGDNATVDWSVGVMNDGNVVADFDSDLKGNGSHSQIKVVGISTGHQTQGIDTRVTNFGLNSVGHILQNGVILDKGTLTFNAIGHIIKGAKNADAQQSSHVLMLSDKGRGDANPILLIDENEVTAGHAASVGQVDEEDLFYLQSRGLDEETAKRLVIRGFLGSVVSEIPVKSVQAEFIETIERKLGM
>NZ_CP028160.1|WP_004255181.1|1940795_1941566_-|Fe-S-cluster-assembly-ATPase-SufC
MATLEIKNLHVAIEDKEILKGVNLVINTNEIHAIMGPNGTGKSTLSAAIMGNPNYSVTQGEVLFDGQNVLEMSVDERARLGLFLAMQYPSEIPGITNAEFLRAAMNAKRAEDDKVSVMEFIKKLDKNMEVLSMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPTFAILDEIDSGLDIDALKVVAKGVNSMRGEKFGALIITHYQRLLDYITPDVVHIMMDGRVVKTGGAELAKRLETEGYVNIAEELGLEYKEEV
>NZ_CP028160.1|WP_021722251.1|1941740_1943072_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MVDTLKEIPFALKFLIVIIITFGISVILTPIMTFVSKAIGAVDKPNERRVNKKPMPSAGGLVIFIAFAIATLFILPHIVHNQPPIHSQPPVHGASHQPIQLVSYFSYIWPFIVGAGIVVLTGLIDDIKEISPKMKLLGLTVAASFIWFFTNARFDNLKIPFGGPLLIFPAWLSFIFTVFWILAITNAINLIDGLDGLASGVSIISLTTMGIVSYFFLPSPNVFLPITIFIMVAAIMGFFPYNYHPAIIYLGDTGALFLGFIISVASLQGLKNATAVAVLTPLLILGVPITDTIMAMVRRKLNRQSIATADKRHLHHRLMALGFTHRGAVLVIYGIASIFAFISILLQFSSRIGGILLVIACLFGLEIFIELVGILGENRQPVLKALKFVGNSSYRDKVLHSDEDADIDENEEDIENHSMIDEEIDEPTQEFPIQNYRRSRNKK
>NZ_CP028160.1|WP_109991145.1|1943074_1943776_-|adaptor-protein-MecA
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAMLGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKNVKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEVTKMSREFLQEYGECLIATRALDVLRKI
>NZ_CP028160.1|WP_004255171.1|1943905_1944640_-|amino-acid-ABC-transporter-ATP-binding-protein
MNEYLIEIKNLHKYFGKNEVLKGLDIQIKKGEVVVMIGPSGSGKSTFLRTMNLLEKPTDGQVYFEGVNIADKSVDVFKHREKMGMVFQQFNLFPNMTVLENLCLAPVKTGKMTKEEAKKTAEDLLQRVGLSDKAEAYPQALSGGQQQRVAIARALAMNPDVMLFDEPTSALDPEMVGEVLAVMQELAKEGMTMVVVTHEMGFAKTVADRVLFMADGTIVEQGKPAQVFDSPKEKRTQDFLAKVL
>NZ_CP028160.1|WP_033899921.1|1944639_1945326_-|amino-acid-ABC-transporter-permease
MNFDFLPKYLPYFNDGMIVTILISAFVVLIGTLLGIVTALAKISKIAPLRWLANIYIEIFRGTPMLVQIMLGFGLMGSLSLPTFQVGILQQDLGRLIPGIIVISLNSGAYMAEIVRAGIEAVPLGQKEAAYSLGIRPKQAMATVILPQALRNILPAVGNEFVTIIKDSSLLYTIGVMEVFNGAQTVANLTYQTISPMLFVALYYFVVTFVVSRLLVLFEKKLGKGYAK
>NZ_CP028160.1|WP_033899919.1|1945473_1946382_-|diacylglycerol-kinase-family-lipid-kinase
MTYYLLANPNSGAGKGARTLETLIPYLEKNNYEYRLFKTKAAGEEGALVRQILDLKNPDDHLVIIGGDGTISLVINELPEEEAFSYIPSGSGNDFARSLKLELDPIESFEAARRGINHEIFIMNYQSKGLSGYALNNIGIGLDATIVKSANEGKLKQVLNKLKLGSFSYILTALHVLITKKPFPALIEVENQEISLENAFLMTFTKHPYFGGGVKISPEATNENADIHLVEYNKHHLLRTFSLIPSVLRGMHLKHPLFLHRVSPQFSVELAESQPVQIDGEIHELVAADRLSISTERRMIIY

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

398503 : 410633

Streptococcus_phage(40.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003131595.1\|398503_398821_+	thioredoxin family protein	A0A0K2FIM3	Achromobacter_phage	4.5e-05	30.4
WP_003131594.1\|398906_399533_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_023188995.1\|399695_401036_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_010905314.1\|401125_401515_+	single-stranded DNA-binding protein	A0A0K0MWE1	Streptococcus_phage	1.4e-24	45.0
WP_003131589.1\|401634_401919_+	co-chaperone GroES	A0A221S386	uncultured_virus	3.1e-13	44.1
WP_109990650.1\|402006_403635_+	chaperonin GroEL	A0A219YK78	uncultured_virus	4.9e-156	56.5
WP_003131583.1\|403681_404494_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	3.1e-34	38.1
WP_010905315.1\|404662_406105_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.4e-32	33.0
WP_003131580.1\|406097_406799_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.2e-42	39.7
WP_012897230.1\|406976_407612_+	dTMP kinase	M1PSC7	Streptococcus_phage	5.4e-74	65.0
WP_003131573.1\|407744_408605_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.0e-67	45.2
WP_010905316.1\|408656_409439_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_011675472.1\|409431_409758_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_033900473.1\|409757_410633_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.3e-99	65.7

DBSCAN-SWA_2

953601 : 990458

Lactococcus_phage(69.23%)

protease,tail,portal,terminase,head,capsid,holin,integrase

attL 952328:952344|attR 995068:995084

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
952328:952344	attL	NA	NA	NA	NA
WP_109990784.1\|953601_954735_-\|integrase	site-specific integrase	A0A059NT56	Lactococcus_phage	9.6e-191	91.8
WP_109990785.1\|954860_955352_-	hypothetical protein	A0A1B1IMF9	Lactococcus_phage	3.1e-45	92.8
WP_109990786.1\|955414_956002_-	hypothetical protein	Q9AZF6	Lactococcus_phage	4.8e-93	85.5
WP_109990787.1\|956014_956383_-	XRE family transcriptional regulator	Q9AZF5	Lactococcus_phage	1.5e-57	87.7
WP_029344191.1\|956676_956868_+	hypothetical protein	Q9AZF4	Lactococcus_phage	4.3e-27	96.8
WP_109991411.1\|956881_957118_+	helix-turn-helix domain-containing protein	A0A059NT59	Lactococcus_phage	5.3e-35	94.9
WP_109990788.1\|957567_958368_-	hypothetical protein	NA	NA	NA	NA
WP_109990789.1\|958428_958938_+	hypothetical protein	Q38337	Lactococcus_phage	1.9e-85	97.6
WP_109990790.1\|958937_959657_+	AAA family ATPase	A0A1P8BMP5	Lactococcus_phage	5.1e-129	97.5
WP_109990791.1\|959643_960990_+	DEAD/DEAH box helicase	A0A1B1IMF3	Lactococcus_phage	4.9e-250	97.8
WP_109990792.1\|961007_961460_+	DUF669 domain-containing protein	Q9G0E5	Lactococcus_phage	3.6e-80	97.3
WP_109990793.1\|961462_962269_+	hypothetical protein	A0A1B1IMF5	Lactococcus_phage	3.6e-152	98.9
WP_109990794.1\|962243_963707_+	DNA primase	A0A1P8BMT9	Lactococcus_phage	1.1e-266	94.4
WP_109990795.1\|963930_964242_+	VRR-NUC domain-containing protein	A0A1P8BMN2	Lactococcus_phage	3.7e-52	98.1
WP_021037754.1\|964348_964522_+	DUF1497 domain-containing protein	A0A1P8BL92	Lactococcus_phage	3.3e-18	84.2
WP_109990796.1\|964518_964725_+	DUF1125 domain-containing protein	A0A1P8BL00	Lactococcus_phage	2.0e-30	98.5
WP_162551433.1\|964717_964864_+	hypothetical protein	NA	NA	NA	NA
WP_109990797.1\|964860_965496_+	hypothetical protein	A0A1W6JNE9	Lactococcus_phage	1.1e-63	57.3
WP_109990798.1\|965512_965935_+	dUTP diphosphatase	A0A1P8BMQ4	Lactococcus_phage	1.8e-46	68.6
WP_162551419.1\|965937_966099_+	hypothetical protein	NA	NA	NA	NA
WP_109990799.1\|966100_966307_+	hypothetical protein	NA	NA	NA	NA
WP_109990800.1\|966303_966654_+	hypothetical protein	A0A059NT79	Lactococcus_phage	8.2e-08	53.0
WP_109990801.1\|966646_967054_+	hypothetical protein	A0A1W6JJV2	Lactococcus_phage	4.3e-08	47.7
WP_162551434.1\|967080_967566_-	hypothetical protein	NA	NA	NA	NA
WP_162551435.1\|967791_967959_+	hypothetical protein	NA	NA	NA	NA
WP_109990804.1\|968122_968353_+	hypothetical protein	Q94M84	Lactococcus_phage	6.7e-35	93.4
WP_162551436.1\|968349_968523_+	hypothetical protein	NA	NA	NA	NA
WP_109990805.1\|968522_968699_+	DUF1660 domain-containing protein	Q94M83	Lactococcus_phage	9.1e-08	51.7
WP_109990806.1\|968841_968979_-	hypothetical protein	NA	NA	NA	NA
WP_162551437.1\|969104_969281_+	hypothetical protein	NA	NA	NA	NA
WP_162551438.1\|969375_969663_+	hypothetical protein	NA	NA	NA	NA
WP_109990808.1\|969708_970011_+	HNH endonuclease	A0A1S5SFB3	Streptococcus_phage	1.4e-24	61.6
WP_023189099.1\|970153_970465_+	hypothetical protein	Q4ZD78	Staphylococcus_phage	1.2e-10	42.0
WP_109990809.1\|970454_972194_+\|terminase	terminase large subunit	A3F641	Streptococcus_phage	5.4e-201	59.8
WP_109990810.1\|972386_973580_+\|portal	phage portal protein	A0A2P0ZLC9	Lactobacillus_phage	2.0e-37	30.2
WP_162551439.1\|973566_974346_+\|protease	Clp protease ClpP	A3F644	Streptococcus_phage	2.7e-43	38.0
WP_109990812.1\|974345_975473_+\|capsid	phage major capsid protein	A3F645	Streptococcus_phage	1.0e-80	47.3
WP_109990813.1\|975533_975800_+	hypothetical protein	A0A1X9IGH3	Lactococcus_phage	6.9e-07	45.7
WP_109990814.1\|975816_976149_+	hypothetical protein	A3F647	Streptococcus_phage	6.8e-12	42.7
WP_109990815.1\|976114_976501_+\|head,tail	phage head-tail adapter protein	A0A1S5SFE6	Streptococcus_phage	8.1e-17	40.9
WP_109990816.1\|976493_976898_+	hypothetical protein	A0A2P0ZLD7	Lactobacillus_phage	3.3e-13	38.9
WP_109990817.1\|976894_977284_+	hypothetical protein	NA	NA	NA	NA
WP_109990818.1\|977298_977877_+\|tail	phage tail protein	A3F651	Streptococcus_phage	1.6e-29	43.5
WP_109990819.1\|977933_978239_+	hypothetical protein	NA	NA	NA	NA
WP_109990820.1\|978514_979030_+	hypothetical protein	NA	NA	NA	NA
WP_109990821.1\|979146_983238_+\|tail	phage tail tape measure protein	A0A1S5SFC1	Streptococcus_phage	1.6e-123	38.6
WP_109990822.1\|983234_984806_+\|tail	phage tail protein	Q8LTK1	Lactococcus_phage	6.7e-243	79.5
WP_109991413.1\|984805_987454_+	hypothetical protein	Q8LTK0	Lactococcus_phage	0.0e+00	46.7
WP_109990823.1\|987708_988038_+	hypothetical protein	Q9AZL1	Lactococcus_phage	4.0e-49	91.6
WP_098403444.1\|988021_988297_+	Holin	A0A182BQ79	Lactococcus_phage	1.6e-14	56.9
WP_109990824.1\|988296_989076_+\|holin	phage holin	Q38323	Lactococcus_phage	1.2e-120	95.8
WP_109990825.1\|989152_989761_+	hypothetical protein	NA	NA	NA	NA
WP_109990826.1\|990260_990458_+	hypothetical protein	A0A2I6QQV7	Streptococcus_phage	2.1e-08	60.4
995068:995084	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1031551 : 1055005

Staphylococcus_phage(21.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003130964.1\|1031551_1032244_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	2.7e-31	34.4
WP_033900035.1\|1032236_1033172_+	ABC transporter permease	NA	NA	NA	NA
WP_012897610.1\|1033274_1034252_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.9e-118	66.0
WP_033900033.1\|1034601_1036770_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	8.6e-257	61.0
WP_003130968.1\|1036905_1037328_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.3e-12	37.3
WP_012897612.1\|1037329_1037548_-	redoxin NrdH	C3U2K9	Lactococcus_phage	7.6e-12	47.6
WP_010905665.1\|1037721_1038363_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_012897614.1\|1038637_1040572_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.1e-125	43.5
WP_033900030.1\|1040776_1041316_+	cysteine hydrolase family protein	NA	NA	NA	NA
WP_058211984.1\|1041308_1042142_+	3'-5' exonuclease	A0A0K2SUJ2	Clostridium_phage	3.1e-21	39.4
WP_033900027.1\|1042138_1042588_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_032946778.1\|1042862_1045337_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	2.1e-97	32.2
WP_003130981.1\|1045362_1046268_-	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_109990835.1\|1046736_1047825_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	3.8e-51	39.1
WP_103054691.1\|1047824_1048475_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.2e-42	44.1
WP_109990836.1\|1048483_1049680_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.6e-111	51.5
WP_003130993.1\|1049707_1050172_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.8e-39	53.7
WP_109990837.1\|1050274_1050727_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_109990838.1\|1050787_1051693_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	7.0e-11	27.8
WP_003130996.1\|1051840_1052284_+	divergent PAP2 family protein	NA	NA	NA	NA
WP_109990839.1\|1052423_1054046_+	hypothetical protein	NA	NA	NA	NA
WP_015426264.1\|1054048_1055005_+	glycosyltransferase family 2 protein	I1TED8	Salmonella_phage	4.0e-49	37.5

DBSCAN-SWA_4

1232733 : 1241155

Lactococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_109990888.1\|1232733_1234200_-	recombinase family protein	A0A141E1W5	Streptococcus_phage	6.5e-99	42.8
WP_109990889.1\|1234320_1234818_-	hypothetical protein	NA	NA	NA	NA
WP_109990890.1\|1235567_1235897_-	hypothetical protein	NA	NA	NA	NA
WP_109990891.1\|1236075_1236306_+	transcriptional regulator	Q77NT7	Lactococcus_phage	1.0e-30	86.8
WP_058209312.1\|1236319_1236499_+	hypothetical protein	NA	NA	NA	NA
WP_109990892.1\|1236482_1236791_+	hypothetical protein	B5SP04	Lactococcus_phage	2.8e-44	94.1
WP_109990893.1\|1236871_1237513_+	hypothetical protein	Q8LTN6	Lactococcus_phage	2.0e-28	36.7
WP_162551443.1\|1237539_1238625_+	recombinase RecT	D7RWF9	Brochothrix_phage	2.8e-30	32.8
WP_109990894.1\|1238602_1239511_+	hypothetical protein	NA	NA	NA	NA
WP_109990895.1\|1239776_1240019_+	hypothetical protein	NA	NA	NA	NA
WP_109990896.1\|1240008_1240422_+	replication terminator protein	A0A097BY30	Enterococcus_phage	2.1e-31	54.6
WP_109990897.1\|1240432_1241155_+	hypothetical protein	A0A097BY87	Enterococcus_phage	4.2e-51	48.6

DBSCAN-SWA_5

1518194 : 1528604

Lactococcus_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_109991038.1\|1518194_1518371_-	hypothetical protein	Q94M83	Lactococcus_phage	2.6e-07	48.3
WP_162551457.1\|1518873_1519464_+	hypothetical protein	NA	NA	NA	NA
WP_021464853.1\|1519646_1520315_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_162551458.1\|1520379_1520550_-	hypothetical protein	NA	NA	NA	NA
WP_109991041.1\|1520677_1520944_-	hypothetical protein	NA	NA	NA	NA
WP_109991042.1\|1520937_1521702_-	helix-turn-helix domain-containing protein	Q9MCG3	Lactococcus_phage	5.1e-95	79.3
WP_104143006.1\|1521701_1522028_-	endonuclease	A0A1X9IGF1	Lactococcus_phage	1.9e-46	79.4
WP_109991043.1\|1522294_1523221_-	recombinase RecT	A0A1P8BKY8	Lactococcus_phage	5.7e-149	93.8
WP_109991044.1\|1524346_1524637_-	hypothetical protein	Q9AZW0	Lactococcus_phage	5.3e-45	90.6
WP_109991045.1\|1524649_1525396_-	phage antirepressor Ant	Q6SEF4	Lactobacillus_prophage	3.2e-62	54.1
WP_109991046.1\|1525407_1525647_-	helix-turn-helix transcriptional regulator	Q38329	Lactococcus_phage	6.5e-33	89.9
WP_109991047.1\|1525800_1526406_+	hypothetical protein	NA	NA	NA	NA
WP_109991049.1\|1526845_1527397_+	helix-turn-helix domain-containing protein	Q38327	Lactococcus_phage	2.3e-57	85.8
WP_109991050.1\|1527407_1527995_+	hypothetical protein	Q9AZW4	Lactococcus_phage	3.6e-93	83.5
WP_058205866.1\|1528009_1528210_+	hypothetical protein	Q9T1Z0	Lactococcus_phage	7.1e-25	93.5
WP_109991051.1\|1528217_1528604_+	DUF898 family protein	S5MNN8	Brevibacillus_phage	2.2e-14	68.8

DBSCAN-SWA_6

1631496 : 1641799

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_109991076.1\|1631496_1633053_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.8e-70	45.9
WP_003130055.1\|1633229_1633772_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	1.8e-09	29.9
WP_109991077.1\|1633908_1634946_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_003130052.1\|1635076_1635607_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_023164306.1\|1635657_1637247_-	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	1.1e-11	34.1
WP_109991078.1\|1637413_1637962_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.6e-18	31.7
WP_057720815.1\|1637990_1639007_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	8.3e-61	41.8
WP_058203028.1\|1639195_1641799_-	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	8.5e-126	33.1

DBSCAN-SWA_7

1846166 : 1856025

Prochlorococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003130886.1\|1846166_1846928_-	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.5e-17	30.0
WP_003130885.1\|1847093_1847903_-	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.0e-10	26.5
WP_003130884.1\|1847936_1848830_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_021722156.1\|1848829_1849753_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_017864882.1\|1849873_1850725_-	phosphate ABC transporter substrate-binding protein	E3SNT9	Prochlorococcus_phage	4.2e-05	27.3
WP_003130880.1\|1851071_1851968_-	phosphate ABC transporter substrate-binding protein	E3SM63	Prochlorococcus_phage	7.2e-08	32.4
WP_003130878.1\|1852245_1852713_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.7e-43	56.6
WP_161934612.1\|1852744_1853311_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_033899354.1\|1853406_1856025_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	7.1e-64	33.3

DBSCAN-SWA_8

2048508 : 2055308

Lactococcus_phage(80.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_109991176.1\|2048508_2049045_-	hypothetical protein	A0A023J2W2	Lactococcus_phage	1.2e-10	58.6
WP_109991177.1\|2049037_2049310_-	hypothetical protein	NA	NA	NA	NA
WP_109991178.1\|2049310_2049829_-	hypothetical protein	G1BQP1	Mycobacterium_virus	9.9e-10	31.9
WP_109991179.1\|2049830_2050079_-	hypothetical protein	Q9AZU9	Lactococcus_phage	2.6e-24	75.0
WP_109991180.1\|2050140_2050455_-	hypothetical protein	NA	NA	NA	NA
WP_109991181.1\|2050447_2050825_-	hypothetical protein	NA	NA	NA	NA
WP_109991431.1\|2051154_2051397_-	hypothetical protein	A0A1P8BL80	Lactococcus_phage	2.4e-06	100.0
WP_109991432.1\|2051411_2051609_-	hypothetical protein	A0A1P8BKA8	Lactococcus_phage	1.7e-23	92.3
WP_109991182.1\|2051824_2052199_-	DUF3850 domain-containing protein	A0A097BYG6	Leuconostoc_phage	6.7e-08	59.2
WP_162551469.1\|2052290_2052614_-	hypothetical protein	NA	NA	NA	NA
WP_109991184.1\|2052696_2053362_-	DUF1642 domain-containing protein	Q9AZ77	Lactococcus_phage	2.8e-65	78.3
WP_109991185.1\|2053662_2054052_-	hypothetical protein	NA	NA	NA	NA
WP_109991186.1\|2054048_2054342_-	hypothetical protein	A0A1B1IMV9	Lactococcus_phage	1.4e-05	33.6
WP_109991187.1\|2054433_2054775_-	hypothetical protein	Q8LTM4	Lactococcus_phage	5.7e-30	62.7
WP_162551470.1\|2054771_2055308_-	DUF1642 domain-containing protein	A0A1P8BMI2	Lactococcus_phage	1.9e-11	35.6

DBSCAN-SWA_9

2504088 : 2568325

Lactococcus_phage(53.49%)

transposase,protease,tail,portal,terminase,tRNA,holin,capsid,integrase

attL 2528233:2528248|attR 2572849:2572864

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003131240.1\|2504088_2505456_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_010906409.1\|2505507_2506254_-	hypothetical protein	NA	NA	NA	NA
WP_109991349.1\|2506253_2508254_-	ATP-dependent DNA helicase RecG	B2CRJ8	Acidianus_filamentous_virus	8.0e-07	23.6
WP_010906411.1\|2508391_2508736_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_003131244.1\|2508805_2509816_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_003131246.1\|2510094_2510616_-	DUF536 domain-containing protein	NA	NA	NA	NA
WP_109991350.1\|2510744_2513438_+	cation-translocating P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	4.0e-70	27.2
WP_021723196.1\|2513478_2514006_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_109991351.1\|2514130_2515150_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_023164731.1\|2515452_2516157_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_033899243.1\|2516180_2516636_+	hypothetical protein	NA	NA	NA	NA
WP_004254378.1\|2522653_2523046_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_010906417.1\|2523065_2523512_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_162551490.1\|2523881_2524952_+	ABC transporter permease	NA	NA	NA	NA
WP_004254370.1\|2524960_2525632_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.5e-34	40.0
WP_109991353.1\|2525776_2526655_+	ribonuclease HIII	NA	NA	NA	NA
WP_012898725.1\|2526666_2527293_+	signal peptidase I	NA	NA	NA	NA
WP_010906422.1\|2527341_2528157_-	pur operon repressor	NA	NA	NA	NA
2528233:2528248	attL	NA	NA	NA	NA
WP_109991354.1\|2529247_2530246_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.4e-62	42.5
WP_109991355.1\|2530426_2530963_+	hypothetical protein	NA	NA	NA	NA
WP_109991356.1\|2531061_2531814_-	DUF4065 domain-containing protein	Q0H268	Geobacillus_phage	2.6e-43	40.4
WP_109991357.1\|2531817_2532462_-	hypothetical protein	Q0H269	Geobacillus_phage	2.3e-24	36.3
WP_109991358.1\|2532734_2533160_-	DUF1761 domain-containing protein	NA	NA	NA	NA
WP_109991359.1\|2533243_2534584_-	LysM peptidoglycan-binding domain-containing protein	A0A1P8BMS7	Lactococcus_phage	7.1e-209	81.7
WP_109991360.1\|2534580_2534931_-\|holin	holin	A0A1X9IGI3	Lactococcus_phage	2.6e-38	70.1
WP_109991361.1\|2534979_2536266_-	hypothetical protein	A0A1P8BKJ2	Lactococcus_phage	1.2e-48	78.5
WP_109991362.1\|2536275_2537394_-	hypothetical protein	Q77MU2	Lactococcus_phage	1.6e-81	43.9
WP_109991363.1\|2537395_2538247_-\|tail	phage tail family protein	Q38129	Lactococcus_phage	2.3e-56	38.6
WP_109991364.1\|2538259_2541739_-\|tail	phage tail tape measure protein	A0A068F1L4	Mycobacterium_phage	1.6e-50	34.1
WP_109991365.1\|2541738_2542311_-	hypothetical protein	M1IEU4	Streptococcus_phage	5.8e-27	36.1
WP_109991366.1\|2542323_2542797_-	hypothetical protein	NA	NA	NA	NA
WP_109991367.1\|2542854_2543157_-	hypothetical protein	NA	NA	NA	NA
WP_109991368.1\|2543197_2543680_-\|tail	phage tail protein	M1IFB9	Streptococcus_phage	1.6e-22	42.5
WP_109991369.1\|2543672_2544086_-\|capsid	capsid protein	A0A286QML6	Streptococcus_phage	4.8e-23	44.0
WP_109991370.1\|2544075_2544447_-\|capsid	capsid protein	B3GW08	Streptococcus_phage	9.2e-26	47.8
WP_109991371.1\|2544446_2544794_-	hypothetical protein	NA	NA	NA	NA
WP_109991372.1\|2544793_2545198_-	hypothetical protein	Q5YA68	Bacillus_phage	7.7e-10	34.9
WP_109991373.1\|2545224_2545473_-	Ig domain-containing protein	A0A1P8BMA7	Lactococcus_phage	1.7e-20	88.7
WP_109991374.1\|2545490_2546444_-\|capsid	phage major capsid protein	Q9T1B7	Listeria_phage	6.1e-122	74.8
WP_109991375.1\|2546454_2547033_-	scaffolding protein	Q9T1B8	Listeria_phage	1.4e-17	34.7
WP_031558864.1\|2547221_2547470_-	hypothetical protein	Q8LTR0	Lactococcus_phage	3.0e-41	98.8
WP_109991376.1\|2547519_2548725_-\|capsid	capsid protein	K4JXL1	Streptococcus_phage	3.4e-93	46.6
WP_109991377.1\|2548721_2550266_-\|portal	phage portal protein	C5IUJ2	Streptococcus_phage	1.5e-122	48.9
WP_162551491.1\|2550267_2551473_-\|terminase	PBSX family phage terminase large subunit	V9QIY4	Oenococcus_phage	5.1e-73	39.3
WP_109991379.1\|2551465_2551861_-	hypothetical protein	A0A0S2MYF8	Enterococcus_phage	6.4e-09	37.0
WP_109991380.1\|2552035_2552494_-	hypothetical protein	A0A1P8BM80	Lactococcus_phage	4.5e-83	98.0
WP_109991381.1\|2552503_2553304_-	hypothetical protein	A0A1X9IGF6	Lactococcus_phage	3.0e-74	53.4
WP_109991382.1\|2553307_2553859_-	LemA family protein	A0A1X9IGG1	Lactococcus_phage	4.8e-63	73.3
WP_109991383.1\|2554325_2554601_-	hypothetical protein	NA	NA	NA	NA
WP_109991384.1\|2554597_2554804_-	hypothetical protein	A0A1P8BMS6	Lactococcus_phage	6.7e-10	46.8
WP_109991385.1\|2554821_2555010_-	hypothetical protein	NA	NA	NA	NA
WP_109991386.1\|2555006_2555432_-	hypothetical protein	A0A1P8BKW0	Lactococcus_phage	3.3e-72	97.8
WP_109991387.1\|2555491_2555863_+	hypothetical protein	NA	NA	NA	NA
WP_162551492.1\|2555792_2556002_-	hypothetical protein	NA	NA	NA	NA
WP_109991388.1\|2556017_2556260_-	hypothetical protein	A5GZ49	Lactococcus_phage	7.5e-37	88.8
WP_109991389.1\|2556252_2557176_-	DnaD domain protein	A5GZ47	Lactococcus_phage	3.4e-146	96.3
WP_109991390.1\|2557300_2557726_-	single-stranded DNA-binding protein	Q9AZV6	Lactococcus_phage	5.7e-64	85.1
WP_109991391.1\|2557718_2558792_-	DUF1351 domain-containing protein	A0A1P8BLG1	Lactococcus_phage	7.5e-129	78.7
WP_109991392.1\|2558793_2559531_-	phage recombination protein Bet	A0A1B1IMV3	Lactococcus_phage	2.5e-131	97.6
WP_109991393.1\|2559634_2559871_-	DUF1408 domain-containing protein	Q9MC36	Lactococcus_phage	1.0e-38	98.7
WP_109991394.1\|2559870_2560068_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_109991395.1\|2560188_2560470_+	DUF3892 domain-containing protein	NA	NA	NA	NA
WP_109991396.1\|2560499_2560691_-	hypothetical protein	A0A1P8BKS3	Lactococcus_phage	4.4e-24	95.2
WP_109991397.1\|2560833_2561079_-	hypothetical protein	A0A1P8BMM2	Lactococcus_phage	4.5e-37	92.5
WP_109991398.1\|2561091_2561844_-	Rha family transcriptional regulator	R9QMT9	Lactococcus_phage	4.3e-62	53.4
WP_015966797.1\|2561862_2562093_-	cro2009	Q77NT7	Lactococcus_phage	6.7e-35	100.0
WP_109991399.1\|2562273_2563035_+	hypothetical protein	NA	NA	NA	NA
WP_109991400.1\|2563191_2564004_+	helix-turn-helix transcriptional regulator	A0A141E0Q5	Streptococcus_phage	5.4e-63	50.2
WP_109991401.1\|2564015_2564339_+	hypothetical protein	NA	NA	NA	NA
WP_109991402.1\|2564389_2565535_+\|integrase	site-specific integrase	A0A1P8BMN3	Lactococcus_phage	3.9e-184	85.3
WP_003129877.1\|2566195_2568325_-	elongation factor G	A0A2K9L6L3	Tupanvirus	4.9e-47	25.7
2572849:2572864	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP028161

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP028161_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028161_1

42821-43015

Orphan

Consensus_repeat	Method
CATATCTGTGACATTACTTGTATCAAAATTAGAAAAATT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP028161_1

>merge|NZ_CP028161|1|42821-43015|PILER-CR
CATTTCTGTAACTTTTCTTGTATCAAAATTAGACAAATTTAGTTTTGATAAAGAAGAGCAGTCATAGAACATCCCGTACATATTTGTGACATTACTTGTATTAAACTGGCTCACATCAATTGCTTTTAGATTTGTACATTCATCAAACATCAAATCCATACCTGTGACATTACTTGTATCAAAGTTAGAAATATT

>NZ_CP028161|1|1|42821-43015|PILER-CR
CATTTCTGTAACTTTTCTTGTATCAAAATTAGACAAATT	TAGTTTTGATAAAGAAGAGCAGTCATAGAACATCCCGTA
CATATTTGTGACATTACTTGTATTAAACTGGCTCACATC	AATTGCTTTTAGATTTGTACATTCATCAAACATCAAATCCATACCTGTGAC
ATTACTTGTATCAAAGTTAGAAATATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028161.1\|WP_162551506.1\|41158_41656_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991484.1\|47860_49108_-\|lipase	unknown	unknown	gnl\|CDD\|238287
NZ_CP028161.1\|WP_109991470.1\|32940_34563_-\|DUF2075-domain-containing-protein	unknown	unknown	gnl\|CDD\|378274
NZ_CP028161.1\|WP_109991472.1\|38924_39398_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991486.1\|49530_49821_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|227179
NZ_CP028161.1\|WP_109991468.1\|31429_31612_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991471.1\|34857_36390_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991478.1\|44156_45230_+\|DUF4352-domain-containing-protein	unknown	unknown	gnl\|CDD\|378684
NZ_CP028161.1\|WP_109991474.1\|40296_40650_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991481.1\|46984_47245_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377503
NZ_CP028161.1\|WP_109991487.1\|50425_51355_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991469.1\|31608_32064_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180915
NZ_CP028161.1\|WP_109991475.1\|40791_41028_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991480.1\|46002_46275_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991483.1\|47531_47849_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991494.1\|37608_38850_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991479.1\|45229_45988_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991482.1\|47268_47529_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991485.1\|49104_49518_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028161.1\|WP_109991473.1\|39394_39991_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737

Protein	Function_ID	Function_description	E-value
NZ_CP028161.1\|WP_109991484.1\|47860_49108_-\|lipase	gnl\|CDD\|238287	cd00519, Lipase_3, Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site. .	1.44899e-08
NZ_CP028161.1\|WP_109991469.1\|31608_32064_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|180915	PRK07275, PRK07275, single-stranded DNA-binding protein; Provisional.	1.71866e-81
NZ_CP028161.1\|WP_109991470.1\|32940_34563_-\|DUF2075-domain-containing-protein	gnl\|CDD\|378274	pfam09848, DUF2075, Uncharacterized conserved protein (DUF2075). This domain, found in various prokaryotic proteins (including putative ATP/GTP binding proteins), has no known function.	8.56256e-06
NZ_CP028161.1\|WP_109991486.1\|49530_49821_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|227179	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown].	1.28543e-22
NZ_CP028161.1\|WP_109991478.1\|44156_45230_+\|DUF4352-domain-containing-protein	gnl\|CDD\|378684	pfam11611, DUF4352, Domain of unknown function (DUF4352). Members of these family are putative lipoproteins that fall into the Antigen MPT63/MPB63 (immunoprotective extracellular protein) superfamily.	6.60284e-07
NZ_CP028161.1\|WP_109991481.1\|46984_47245_-\|hypothetical-protein	gnl\|CDD\|377503	pfam05360, YiaAB, yiaA/B two helix domain. This domain consists of two transmembrane helices and a conserved linking section.	3.00074e-12
NZ_CP028161.1\|WP_109991473.1\|39394_39991_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	3.85361e-44

>NZ_CP028161.1|WP_162551506.1|41158_41656_-|hypothetical-protein
MPKYKLTALIGVSLNSIVVVFAFLFDFLSMVKDQQFLNNTNEQIAALGGNETNMTITFGIQSMILVTFTIISLVLCLVSWIAFSQLAHKNSFGWEIYLLTLSLFSFLSGFGNLIGVFMGGNKIIYEDILLSFLKISCSIFLVLSFIFWKIHYDEKKLKMMNKNEL
>NZ_CP028161.1|WP_109991475.1|40791_41028_-|hypothetical-protein
MVLEMTYKEDLERSKSILDIQQAYERECHRRFLVLQEMFPDDSARMMLSEHLTIWLAAEKVAVGKFGISDRHWIQEKI
>NZ_CP028161.1|WP_109991474.1|40296_40650_-|hypothetical-protein
MNQLSIIFLITLLMIFSIVVLVFFMIKHNLNTKGKYQLYWTTQKNLFSIKVNKGQFFVRADNLELAKKVGAKALQNKYQNKEWFEDIRFTVRGGGEKSMLSQGNWEILINILEERNQ
>NZ_CP028161.1|WP_109991473.1|39394_39991_-|recombinase-family-protein
MSKIGYARVSSKEQNLDRQLESLNYVSKVFSDKVSGQSTERPQLKAMLEYIREGDIVVVTELDRLGRNNKDLTTIMNEIQQKGATLEVLNLPSMNGIDDENLRRLINNLVIELYKYQAEAERKKIKERQKQGIKIAKEKGKFKGGKRKFQENDPRLNLAFELYLKGYTDKEVEEQIGINRRTFRRYRDRLGIHRKKKQ
>NZ_CP028161.1|WP_109991472.1|38924_39398_-|hypothetical-protein
MRIRYNRQSILDNNLGVIYVLLLLLLIFTFILKGTLALIGSLFIGSMLFISIILTIFDRRKKDVLTWNDNFFEINNSFFKKIKIEFSTVKRILIVKKKEVDSVPRDLPNSYEIFVELHIFDKKLNRQIFTLGDERYINETDTEAFLTYCKLKDIDIS
>NZ_CP028161.1|WP_109991494.1|37608_38850_+|hypothetical-protein
MAFNCFFIYNCKMNVKLPLKVYNSFLKILLISLILITISVFLLVTLLSEINVTIIITGLLLLFLGLWILFIGFKNRKTPLITVQDEGLSSQSFKKYGMIPWHEIKNLRYEIVQAGRSTQYYLYVDVFHPEDYQTEKQKAFRKKHPLLDEWRKSFNRLGEDTAFTIPLVNIKRREQTANQIIEVWQERRKIVPEEEMFDNRNQLLNDGIVPAIIKSEDTSNFKYRLWTLLIVLAILLVGFFGYFQKKAKTQNNFMVNKNYLVIDENTKNTEFGFKLYPKITKVPLAFIGNYVDFSDNNSQNKEIDNWKFTFKKMSKEHISDDESFDNKVVRMVTITAIKNSKSKLVFEFKHKEKGKQIGGGDEVTGWDYAQFDNINLTKEGYTATLNYKEDGDIQTVKVLVLEEKDAFHYLKNK
>NZ_CP028161.1|WP_109991471.1|34857_36390_-|hypothetical-protein
MDLQKKRNKQGKEFFEYYFINRNYHSNLDQFLEKKFFDEDELSRYIKRLKDAVNSLSIKIEPNWAIPILIYATEKIYYDVSSKKDFKEYGPAIKQSIPLIWTNNFKPHGEQKNYKLLGDIISLNILLFKVRNAQALILNDNDKEAKVGFSVDKDGNVIYSESTYKYMLNNYMLPSVSKYGKDQRTNKSSTKLMKNFLAYYNNVYNVLQGVEPRTIDFFKGTVLYYFKGISDQNYKNFWQELYARLTVLILLTSYSSTDNDKPIIFIFSTLYILNKEKTLFNQETFNNLIWTNSHMNNEKMFDHNAIVNRPILRIENSSETYYATSVGLLIDNINHFIEASVFKIQSIPNIKNLKDEKNSPFVTQFSEKFEEDTIHLFLKYTKMAGNVNNKGIWNYSNEYVNLKQYNTDNFPGEIDCLAEFSNSKEIYLVECKVMNDAYTEKNYKSTLQQIQKFRMKLSKKENWIKSVFKEYQVYPILLLDKSIFIKKENSKDNIMLMNYDDLEEKLKEIY
>NZ_CP028161.1|WP_109991470.1|32940_34563_-|DUF2075-domain-containing-protein
MDIIMDFKTMLSYLVSQDDEISLRNDIKHEEVYEILENKFASIMPKFKTKGYKFKDTTEVLTFAKFVFLLQEWGLKDIQFYKNTNSFLFGYIIPQINKEFDLLRFGENYNISIELKSKTTVEAQKEQLCKNYFYLNFLSTKTRYISISPDISSYIEYIPSENKYVNLSGTEICDIIIKQVFLEYNTKEVDSFFDIKNYLVSPFNDVEKFLDDKYFLTPHQNQIVKKITEPSDKKTFGIKGNPGTGKSLLVYHICKKLMEKNKKVAIVHGANLNNGQERLALHGFTIFPIRSILSVLDNAWKYDYIIVDEAQRLRQDKGEQYTKLVKAIESSQTKFIISLDGKQTLDKYEKEENSNKLFEYIKDKGETFSLKDKFRTNPEMSRFIQLLFKIPMYKKIDLISNVDHNIIIKYFDNRESGNKYISDMDSNSNWEVLNYTKDRYNQRGIDNMCDTGLTSHSIIGQEFDKVIVPLDSNFFYKEQTIIDRNTGENKIIKLLETTDNYYPLEKMLYQNLTRTREKIEFVIIGNRSIFNEICGLLDSF
>NZ_CP028161.1|WP_109991469.1|31608_32064_+|single-stranded-DNA-binding-protein
MINNVTLVGRLTRDPELRYTPQNQAVTTFSLAVNRQFKNANGDREADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADSFQMLESRQERGNVPTPPPSETQNNQKQSSPADSHDPFANSEPMNINDDDLPF
>NZ_CP028161.1|WP_109991468.1|31429_31612_+|hypothetical-protein
MTEELKANRKWEAKNPDKTKHDTARRQARRYIRDFATEEDISEIKTWLELVEQRRNEEII
>NZ_CP028161.1|WP_109991478.1|44156_45230_+|DUF4352-domain-containing-protein
MKIKQTLALCGTALLTVGLLASCGTKTSVPAKIDVKSGTYVLESGKTAESGEGWLALNVGIKNTSGSTMNGIYDGSFKLYDSKGNQLSTESVYGNDNSKFKTLQAGNLSPDKTLDGYIAFQVDKGEKYELHFSPMPSGADKKPDDIVVKVDTSKYKDPTKELTTLAQSYVDSVFLGKTGVKSELTNDLTKAHNDFNALFSKKFPQESEIQDYYTPSQAELGKIVTSFEAENAKRGKVEYGISEMFPDYAVVTVSPTVLKFSDVNADSIMTTWENQNEGKFDDYDAAMTAASKYLVQNISQKFANTPTSQPSNMNKGGEKLILTKEKSGKWTVDDKDSDKNYDFKNIQSDFMGGMNNY
>NZ_CP028161.1|WP_109991479.1|45229_45988_+|hypothetical-protein
MKKIISIKRPFPLIIVISCFLGIVGSAFFYHRSLPDYAAMNAAKAIKTDNFKRFLKFVPEFSNHQKITKSEFDQFVRAKKKTTVEKIKKDLLNKESFKEISQGFFGIHQFLPIARQIDLTTEDDASTLTLAGEHLKTGEHAGPFIPAYYKIDYKLTSPEYGKIAKTASIDLINQDGILDIQEKTNFLMEKNVQEGFLNLYTGYIQSFANCINNDFDFNKLDNTSNTWSQSLNDYYGILKMRLKVIRKVFRPL
>NZ_CP028161.1|WP_109991480.1|46002_46275_+|hypothetical-protein
MKMDNDNRVEFDAYVDIKIGIQVKGKTTELDNRSNVTVTAIFDNDLNQWVIDNENWEVSSENPKVWMHKIKKVLDKPIIASWSTTSFDSV
>NZ_CP028161.1|WP_109991481.1|46984_47245_-|hypothetical-protein
MKKKVYRNTAAFKLLAWGSFALFVILILIGLYTLKEPLMVKGYYLMGTVGVISSAFTIAKVTRDDQEDDERYNEMFRAVKQENTEK
>NZ_CP028161.1|WP_109991482.1|47268_47529_-|hypothetical-protein
MDIVEELLKKAKKELEKIKIQTLGIHGSMTSSGQRMTIQEKSEEEVKNSKSGLSKNTSELKSAIKGKFSDKLTETFEDQKQMLDNI
>NZ_CP028161.1|WP_109991483.1|47531_47849_-|hypothetical-protein
MLTEDELLLEYRYQRSSLEEQGDELYRGEQSVNNMIEQTSSEISRMLEELGGDPSEASQFARYRLNQVSQEMNESFEFEKRQIQNKIEDTEVTFNQQLRQLHEEG
>NZ_CP028161.1|WP_109991484.1|47860_49108_-|lipase
MTPKDYEGLAKKAYSVDSNFKDGKVTHKGQEFNLNGKRWKVLEAEDNQGNGFQGMAVAPMNNGKPDTSQIVVAYAGTNSSDWKDLAIDGVNVMESFHGFQLNSANKFAEKIEKSYPNSDISSTGHSLGAFLSLAEGAEHHWQTVTFNGPDPYSVLSPQAKKWVKENPGMLTNFLNQMDLVGYGGDIVGRFKNGKLLWSVLGVKMSTTGSEVVLDYGFQGINPLNYHDIDLWKFDKNGNLLDGKGKSHKIPEQAVLNSSMNLLANSFKVQMKSLGDLKKRLTSSGGGLSSGEKIYLDDAQALAIVSTASAEFDLAMLNVMKVYQNGIRKQEELWQKTLDKARSMGSLLESWEINDALESTGFTHENIVAFPVGQYQNKISKVKAMSEQFNSLESEIKGKISELVARDSELAQQLKG
>NZ_CP028161.1|WP_109991485.1|49104_49518_-|hypothetical-protein
MKQKKGLIVLVSLAVVVFILLLGIGGKRYMDRKKTDTNFENQRKAALALRKEEPHMTKIEFTSEGSRPGIGIPWTVGAKVTMDDEVFNMSVEADGDYSVDFDTTEDGDKYDEIHKKKESSKLSLEIIYSNGEREEIK
>NZ_CP028161.1|WP_109991486.1|49530_49821_-|WXG100-family-type-VII-secretion-target
MSQISVTPEELKSQAQVYLQSKDQIEQAIQRVNSMNSTIVEEWKGQAFQAYLEQYNQLEQNVRKFEELLESINQQLNKYADTVAERDAQDAQSFGF
>NZ_CP028161.1|WP_109991487.1|50425_51355_+|hypothetical-protein
MCNEPKESYCNSHSVPQFSLKTIAENGKLLQSAALLNAASLEDKKGVKNSGVFHIICNSCDKLYFRDYENIDNIVKKPTDKIMGQIAVKNFLLQISKRLAEQNLYQEQFRKINRSITFESKLEDINLDLKDYFLDYEINKDVVDNNRKNAYHILFWDILPYKIPIASQGAITLKKDYKNYPVNNVYDTSPDICMQSFHLLTLPLENQSVVLAFYHKKDKLYSQLRHQLNSIKKEDVLKYLNYIIFKETENYYISTKIEEKIFSNKRLLELAAEHNELPNLGMVNLFNLHNYKPVEIDEIPNLLSEEWAL

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP028161_1	1.1\|42860\|39\|NZ_CP028161\|PILER-CR	42860-42898	39	NZ_CP028161	Lactococcus lactis subsp. lactis strain 14B4 plasmid p14B4, complete sequence	42860-42898	0	1.0
NZ_CP028161_1	1.2\|42938\|51\|NZ_CP028161\|PILER-CR	42938-42988	51	NZ_CP028161	Lactococcus lactis subsp. lactis strain 14B4 plasmid p14B4, complete sequence	42926-42976	0	1.0

1. spacer 1.1|42860|39|NZ_CP028161|PILER-CR matches to NZ_CP028161 (Lactococcus lactis subsp. lactis strain 14B4 plasmid p14B4, complete sequence) position: , mismatch: 0, identity: 1.0

tagttttgataaagaagagcagtcatagaacatcccgta	CRISPR spacer
tagttttgataaagaagagcagtcatagaacatcccgta	Protospacer
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2. spacer 1.2|42938|51|NZ_CP028161|PILER-CR matches to NZ_CP028161 (Lactococcus lactis subsp. lactis strain 14B4 plasmid p14B4, complete sequence) position: , mismatch: 0, identity: 1.0

ctggctcacatcaattgcttttagatttgtacattcatcaaacatcaaatc	CRISPR spacer
ctggctcacatcaattgcttttagatttgtacattcatcaaacatcaaatc	Protospacer
***************************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP028160

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP028161

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection