CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP029674	Staphylococcus aureus strain AR_0219 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP029675	Staphylococcus aureus strain AR_0219 chromosome, complete genome	10 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	6	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP029675_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_1

187870-187954

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_1

>merge|NZ_CP029675|1|187870-187954|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>NZ_CP029675|1|1|187870-187954|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000290397.1\|184627_186115_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143435
NZ_CP029675.1\|WP_001230679.1\|179995_180883_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	unknown	unknown	gnl\|CDD\|187543
NZ_CP029675.1\|WP_001291020.1\|178222_179428_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340825
NZ_CP029675.1\|WP_000826669.1\|190005_190977_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NZ_CP029675.1\|WP_000171919.1\|188397_188910_+\|DUF4242-domain-containing-protein	unknown	unknown	gnl\|CDD\|379428
NZ_CP029675.1\|WP_000706135.1\|193528_194554_+\|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
NZ_CP029675.1\|WP_000356963.1\|188015_188219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000197961.1\|190973_191735_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NZ_CP029675.1\|WP_001013485.1\|186761_187721_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_CP029675.1\|WP_000480603.1\|183485_183812_-\|staphylobilin-forming-heme-oxygenase-IsdI	unknown	unknown	gnl\|CDD\|183968
NZ_CP029675.1\|WP_000825098.1\|179438_179996_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|225059
NZ_CP029675.1\|WP_000826862.1\|194939_196190_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP029675.1\|WP_000590854.1\|189251_189992_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_CP029675.1\|WP_000239647.1\|177016_178222_+\|capsular-polysaccharide-biosynthesis-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000605281.1\|196636_203812_+\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
NZ_CP029675.1\|WP_001092004.1\|192995_193355_+\|DUF2294-domain-containing-protein	unknown	unknown	gnl\|CDD\|227896
NZ_CP029675.1\|WP_000723436.1\|182275_183421_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458
NZ_CP029675.1\|WP_000171645.1\|191747_192779_+\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_CP029675.1\|WP_000779504.1\|180936_182199_+\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
NZ_CP029675.1\|WP_001237004.1\|183818_184202_-\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000290397.1\|184627_186115_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NZ_CP029675.1\|WP_001230679.1\|179995_180883_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.93098e-117
NZ_CP029675.1\|WP_001291020.1\|178222_179428_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	3.56278e-74
NZ_CP029675.1\|WP_000826669.1\|190005_190977_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.75927e-52
NZ_CP029675.1\|WP_000171919.1\|188397_188910_+\|DUF4242-domain-containing-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
NZ_CP029675.1\|WP_000706135.1\|193528_194554_+\|NAD-dependent-formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NZ_CP029675.1\|WP_000197961.1\|190973_191735_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
NZ_CP029675.1\|WP_001013485.1\|186761_187721_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.11026e-108
NZ_CP029675.1\|WP_000480603.1\|183485_183812_-\|staphylobilin-forming-heme-oxygenase-IsdI	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
NZ_CP029675.1\|WP_000825098.1\|179438_179996_+\|sugar-transferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.08096e-87
NZ_CP029675.1\|WP_000826862.1\|194939_196190_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
NZ_CP029675.1\|WP_000590854.1\|189251_189992_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.18703e-112
NZ_CP029675.1\|WP_001092004.1\|192995_193355_+\|DUF2294-domain-containing-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
NZ_CP029675.1\|WP_000605281.1\|196636_203812_+\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_CP029675.1\|WP_000723436.1\|182275_183421_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
NZ_CP029675.1\|WP_000171645.1\|191747_192779_+\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67474e-20
NZ_CP029675.1\|WP_000779504.1\|180936_182199_+\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP029675.1\|WP_001237004.1\|183818_184202_-\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	5.80598e-41

>NZ_CP029675.1|WP_001013485.1|186761_187721_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILVAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>NZ_CP029675.1|WP_000290397.1|184627_186115_+|aldehyde-dehydrogenase-family-protein
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>NZ_CP029675.1|WP_001237004.1|183818_184202_-|YbaN-family-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>NZ_CP029675.1|WP_000480603.1|183485_183812_-|staphylobilin-forming-heme-oxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>NZ_CP029675.1|WP_000723436.1|182275_183421_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLADLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK
>NZ_CP029675.1|WP_000779504.1|180936_182199_+|nucleotide-sugar-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEVYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLEKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDICLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>NZ_CP029675.1|WP_001230679.1|179995_180883_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLTYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>NZ_CP029675.1|WP_000825098.1|179438_179996_+|sugar-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>NZ_CP029675.1|WP_001291020.1|178222_179428_+|glycosyltransferase-family-4-protein
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKPLVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>NZ_CP029675.1|WP_000239647.1|177016_178222_+|capsular-polysaccharide-biosynthesis-protein
MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSILTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFLYFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYYLIQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLYLDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKTNLFAIAALCLVMIICYPITLIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLNTKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKSKFINKKDVD
>NZ_CP029675.1|WP_000356963.1|188015_188219_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>NZ_CP029675.1|WP_000171919.1|188397_188910_+|DUF4242-domain-containing-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>NZ_CP029675.1|WP_000590854.1|189251_189992_+|ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNVIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEDRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIMETFALNHHQVEPEYYL
>NZ_CP029675.1|WP_000826669.1|190005_190977_+|ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>NZ_CP029675.1|WP_000197961.1|190973_191735_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>NZ_CP029675.1|WP_000171645.1|191747_192779_+|acyl-CoA/acyl-ACP-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>NZ_CP029675.1|WP_001092004.1|192995_193355_+|DUF2294-domain-containing-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>NZ_CP029675.1|WP_000706135.1|193528_194554_+|NAD-dependent-formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKAIGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSSSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>NZ_CP029675.1|WP_000826862.1|194939_196190_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>NZ_CP029675.1|WP_000605281.1|196636_203812_+|non-ribosomal-peptide-synthetase
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKDATPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHRNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPEAIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSGLNVAQLQQAVQHLIARHEILRTQYIVVDDEVRQRIVADVVADFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQQLINKHRVTVASIPLQMCSIMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENVILAIRGISDCVVTVSHFDTHDILNAYYVGEQQVEQDLKQYLNDQLPKYMIPKTITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMYQNQQSLVALPDNLSELQKIVMSRYNLGILEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: NZ_CP029675_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_2

427653-427754

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_2

>merge|NZ_CP029675|2|427653-427754|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NZ_CP029675|2|2|427653-427754|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000868259.1\|418728_419112_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000211677.1\|417694_417904_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000633907.1\|436773_436974_-\|DUF3173-family-protein	unknown	unknown	gnl\|CDD\|371495
NZ_CP029675.1\|WP_001792089.1\|425359_425458_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000421410.1\|430569_431148_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP029675.1\|WP_000746679.1\|419381_420008_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP029675.1\|WP_000466748.1\|417404_417656_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP029675.1\|WP_000424963.1\|433944_435486_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP029675.1\|WP_000991018.1\|423886_425275_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP029675.1\|WP_000052781.1\|421990_422560_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP029675.1\|WP_001287099.1\|423051_423807_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP029675.1\|WP_000845143.1\|437471_437702_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378900
NZ_CP029675.1\|WP_000793018.1\|431147_432416_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP029675.1\|WP_000956137.1\|427770_428727_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP029675.1\|WP_000930514.1\|420451_421975_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP029675.1\|WP_000264071.1\|432453_433920_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP029675.1\|WP_000158375.1\|418081_418663_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP029675.1\|WP_000394690.1\|428844_429507_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000237797.1\|435553_436747_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP029675.1\|WP_000763767.1\|429649_430057_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000763767.1\|429649_430057_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
NZ_CP029675.1\|WP_000845143.1\|437471_437702_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378900	pfam12645, HTH_16, Helix-turn-helix domain. This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.	2.04673e-25
NZ_CP029675.1\|WP_000746679.1\|419381_420008_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
NZ_CP029675.1\|WP_000421410.1\|430569_431148_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NZ_CP029675.1\|WP_000466748.1\|417404_417656_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
NZ_CP029675.1\|WP_000424963.1\|433944_435486_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP029675.1\|WP_000991018.1\|423886_425275_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP029675.1\|WP_000052781.1\|421990_422560_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NZ_CP029675.1\|WP_001287099.1\|423051_423807_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	4.50551e-88
NZ_CP029675.1\|WP_000793018.1\|431147_432416_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.06593e-169
NZ_CP029675.1\|WP_000956137.1\|427770_428727_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416
NZ_CP029675.1\|WP_000930514.1\|420451_421975_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP029675.1\|WP_000633907.1\|436773_436974_-\|DUF3173-family-protein	gnl\|CDD\|371495	pfam11372, DUF3173, Domain of unknown function (DUF3173). This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).	2.02242e-22
NZ_CP029675.1\|WP_000158375.1\|418081_418663_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
NZ_CP029675.1\|WP_000237797.1\|435553_436747_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.36769e-47
NZ_CP029675.1\|WP_000264071.1\|432453_433920_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0

>NZ_CP029675.1|WP_001792089.1|425359_425458_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG
>NZ_CP029675.1|WP_000991018.1|423886_425275_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>NZ_CP029675.1|WP_001287099.1|423051_423807_+|NADPH-dependent-oxidoreductase
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP029675.1|WP_000052781.1|421990_422560_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP029675.1|WP_000930514.1|420451_421975_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP029675.1|WP_000746679.1|419381_420008_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP029675.1|WP_000868259.1|418728_419112_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMYPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>NZ_CP029675.1|WP_000158375.1|418081_418663_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>NZ_CP029675.1|WP_000211677.1|417694_417904_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFYPILSTFSNIIIHIDHFHANKKDDN
>NZ_CP029675.1|WP_000466748.1|417404_417656_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>NZ_CP029675.1|WP_000956137.1|427770_428727_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP029675.1|WP_000394690.1|428844_429507_-|hypothetical-protein
MEFKTIQSIKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP029675.1|WP_000763767.1|429649_430057_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>NZ_CP029675.1|WP_000421410.1|430569_431148_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_CP029675.1|WP_000793018.1|431147_432416_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFILAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP029675.1|WP_000264071.1|432453_433920_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP029675.1|WP_000424963.1|433944_435486_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP029675.1|WP_000237797.1|435553_436747_-|site-specific-integrase
MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEAREEYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFDKMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGNVKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDIDFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQTDFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDRLGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKEMKKVQ
>NZ_CP029675.1|WP_000633907.1|436773_436974_-|DUF3173-family-protein
MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLDRVPREAVEEILGIRFSNENRSE
>NZ_CP029675.1|WP_000845143.1|437471_437702_-|helix-turn-helix-domain-containing-protein
MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMTDEYGNSHMVIDETLRGRMETKLISKILSFEIK

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Crispr_ID: NZ_CP029675_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_3

841777-841855

Unclear

Consensus_repeat	Method
TGTAGAATTTCTTTTCGAAATTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_3

>merge|NZ_CP029675|3|841777-841855|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCT

>NZ_CP029675|3|3|841777-841855|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCT	CTGTGTTGGGGCCCCGCCAACTTGCATTGCC
TGTAGAATTTCTTTTCGAAATTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000538141.1\|835458_836109_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP029675.1\|WP_000513305.1\|843051_843891_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP029675.1\|WP_000816304.1\|852129_853032_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP029675.1\|WP_000753319.1\|834445_835285_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP029675.1\|WP_001224793.1\|843898_844384_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP029675.1\|WP_001790092.1\|832653_832758_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000617735.1\|829094_829667_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP029675.1\|WP_000229241.1\|836610_838596_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP029675.1\|WP_001792175.1\|834190_834298_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000662676.1\|838603_841450_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP029675.1\|WP_000958224.1\|842113_843046_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP029675.1\|WP_000369722.1\|847777_848689_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP029675.1\|WP_001248939.1\|848685_849681_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP029675.1\|WP_000638419.1\|836105_836342_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP029675.1\|WP_010956549.1\|832926_834037_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP029675.1\|WP_000506531.1\|830080_832612_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP029675.1\|WP_001049165.1\|851299_851887_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP029675.1\|WP_000006551.1\|849791_850736_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP029675.1\|WP_000057543.1\|844391_845831_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP029675.1\|WP_000134963.1\|845897_846833_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000538141.1\|835458_836109_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP029675.1\|WP_000513305.1\|843051_843891_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NZ_CP029675.1\|WP_000816304.1\|852129_853032_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
NZ_CP029675.1\|WP_000753319.1\|834445_835285_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
NZ_CP029675.1\|WP_001224793.1\|843898_844384_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP029675.1\|WP_000958224.1\|842113_843046_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP029675.1\|WP_000617735.1\|829094_829667_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP029675.1\|WP_000229241.1\|836610_838596_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP029675.1\|WP_000506531.1\|830080_832612_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP029675.1\|WP_000662676.1\|838603_841450_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP029675.1\|WP_000369722.1\|847777_848689_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP029675.1\|WP_001248939.1\|848685_849681_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP029675.1\|WP_000638419.1\|836105_836342_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP029675.1\|WP_010956549.1\|832926_834037_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP029675.1\|WP_001049165.1\|851299_851887_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP029675.1\|WP_000006551.1\|849791_850736_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP029675.1\|WP_000057543.1\|844391_845831_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP029675.1\|WP_000134963.1\|845897_846833_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154

>NZ_CP029675.1|WP_000662676.1|838603_841450_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDELTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP029675.1|WP_000229241.1|836610_838596_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP029675.1|WP_000638419.1|836105_836342_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP029675.1|WP_000538141.1|835458_836109_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP029675.1|WP_000753319.1|834445_835285_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP029675.1|WP_001792175.1|834190_834298_+|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NZ_CP029675.1|WP_010956549.1|832926_834037_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP029675.1|WP_001790092.1|832653_832758_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP029675.1|WP_000506531.1|830080_832612_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP029675.1|WP_000617735.1|829094_829667_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_CP029675.1|WP_000958224.1|842113_843046_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP029675.1|WP_000513305.1|843051_843891_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP029675.1|WP_001224793.1|843898_844384_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP029675.1|WP_000057543.1|844391_845831_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP029675.1|WP_000134963.1|845897_846833_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP029675.1|WP_000369722.1|847777_848689_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP029675.1|WP_001248939.1|848685_849681_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP029675.1|WP_000006551.1|849791_850736_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP029675.1|WP_001049165.1|851299_851887_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP029675.1|WP_000816304.1|852129_853032_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP029675_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_4

905255-905336

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_4

>merge|NZ_CP029675|4|905255-905336|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP029675|4|4|905255-905336|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000589549.1\|903199_903556_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP029675.1\|WP_001183854.1\|910206_911058_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP029675.1\|WP_000732324.1\|908603_909425_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP029675.1\|WP_000571207.1\|906872_907898_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP029675.1\|WP_000255551.1\|899011_899629_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP029675.1\|WP_001065801.1\|906326_906623_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP029675.1\|WP_000662306.1\|904157_904271_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000752917.1\|909778_909973_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP029675.1\|WP_000150011.1\|901246_901963_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP029675.1\|WP_000168845.1\|911385_912147_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP029675.1\|WP_001147952.1\|902735_903056_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP029675.1\|WP_000974460.1\|900676_901099_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP029675.1\|WP_001018962.1\|905947_906334_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP029675.1\|WP_000569884.1\|899783_900278_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP029675.1\|WP_000290491.1\|903713_904094_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP029675.1\|WP_000422908.1\|902045_902585_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP029675.1\|WP_000520231.1\|907890_908586_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP029675.1\|WP_000205567.1\|912244_913552_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP029675.1\|WP_000932225.1\|904272_905151_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP029675.1\|WP_001006450.1\|913657_914908_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000589549.1\|903199_903556_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP029675.1\|WP_001183854.1\|910206_911058_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	7.67366e-77
NZ_CP029675.1\|WP_000732324.1\|908603_909425_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.02861e-112
NZ_CP029675.1\|WP_000571207.1\|906872_907898_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	1.76735e-170
NZ_CP029675.1\|WP_000255551.1\|899011_899629_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.60719e-61
NZ_CP029675.1\|WP_001065801.1\|906326_906623_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP029675.1\|WP_000752917.1\|909778_909973_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP029675.1\|WP_000150011.1\|901246_901963_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	3.2619e-146
NZ_CP029675.1\|WP_000168845.1\|911385_912147_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP029675.1\|WP_001147952.1\|902735_903056_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
NZ_CP029675.1\|WP_000974460.1\|900676_901099_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP029675.1\|WP_001018962.1\|905947_906334_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP029675.1\|WP_000569884.1\|899783_900278_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP029675.1\|WP_000290491.1\|903713_904094_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
NZ_CP029675.1\|WP_000422908.1\|902045_902585_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP029675.1\|WP_000520231.1\|907890_908586_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	7.66296e-99
NZ_CP029675.1\|WP_000205567.1\|912244_913552_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.36148e-135
NZ_CP029675.1\|WP_000932225.1\|904272_905151_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	3.13065e-77
NZ_CP029675.1\|WP_001006450.1\|913657_914908_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0

>NZ_CP029675.1|WP_000932225.1|904272_905151_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLSQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQVHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP029675.1|WP_000662306.1|904157_904271_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>NZ_CP029675.1|WP_000290491.1|903713_904094_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>NZ_CP029675.1|WP_000589549.1|903199_903556_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP029675.1|WP_001147952.1|902735_903056_-|thioredoxin-family-protein
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP029675.1|WP_000422908.1|902045_902585_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP029675.1|WP_000150011.1|901246_901963_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP029675.1|WP_000974460.1|900676_901099_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP029675.1|WP_000569884.1|899783_900278_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP029675.1|WP_000255551.1|899011_899629_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIISPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_CP029675.1|WP_001018962.1|905947_906334_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP029675.1|WP_001065801.1|906326_906623_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP029675.1|WP_000571207.1|906872_907898_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVNMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP029675.1|WP_000520231.1|907890_908586_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP029675.1|WP_000732324.1|908603_909425_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP029675.1|WP_000752917.1|909778_909973_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP029675.1|WP_001183854.1|910206_911058_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP029675.1|WP_000168845.1|911385_912147_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP029675.1|WP_000205567.1|912244_913552_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP029675.1|WP_001006450.1|913657_914908_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP029675_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_5

1694413-1694497

Orphan

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_5

>merge|NZ_CP029675|5|1694413-1694497|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>NZ_CP029675|5|5|1694413-1694497|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTGTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_001019324.1\|1702723_1703308_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224627
NZ_CP029675.1\|WP_001282563.1\|1697134_1698109_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
NZ_CP029675.1\|WP_000182211.1\|1691244_1691871_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237622
NZ_CP029675.1\|WP_000084830.1\|1701650_1702367_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP029675.1\|WP_000048060.1\|1684550_1684727_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP029675.1\|WP_000953309.1\|1698165_1700313_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
NZ_CP029675.1\|WP_001274017.1\|1696838_1697090_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NZ_CP029675.1\|WP_000034716.1\|1689343_1691176_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP029675.1\|WP_001104607.1\|1687126_1688065_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NZ_CP029675.1\|WP_000439693.1\|1700371_1700833_-\|ComE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
NZ_CP029675.1\|WP_001088020.1\|1702369_1702723_-\|ribosome-silencing-factor	unknown	unknown	gnl\|CDD\|223870
NZ_CP029675.1\|WP_000368338.1\|1694669_1696493_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP029675.1\|WP_001802022.1\|1700924_1701611_-\|ComEA-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|224472
NZ_CP029675.1\|WP_000108668.1\|1685019_1686366_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
NZ_CP029675.1\|WP_000627144.1\|1691902_1692880_-\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|273017
NZ_CP029675.1\|WP_000218103.1\|1692979_1694104_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP029675.1\|WP_000725167.1\|1703297_1703867_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
NZ_CP029675.1\|WP_001190120.1\|1686372_1687125_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
NZ_CP029675.1\|WP_001119021.1\|1688068_1689208_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237656
NZ_CP029675.1\|WP_001802667.1\|1683623_1684307_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223961

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_001019324.1\|1702723_1703308_-\|HD-domain-containing-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
NZ_CP029675.1\|WP_001282563.1\|1697134_1698109_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	4.1415e-104
NZ_CP029675.1\|WP_000182211.1\|1691244_1691871_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
NZ_CP029675.1\|WP_000084830.1\|1701650_1702367_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.79783e-16
NZ_CP029675.1\|WP_000048060.1\|1684550_1684727_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
NZ_CP029675.1\|WP_000953309.1\|1698165_1700313_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.49563e-90
NZ_CP029675.1\|WP_001274017.1\|1696838_1697090_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17
NZ_CP029675.1\|WP_000034716.1\|1689343_1691176_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP029675.1\|WP_001104607.1\|1687126_1688065_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.7051e-134
NZ_CP029675.1\|WP_000439693.1\|1700371_1700833_-\|ComE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
NZ_CP029675.1\|WP_001088020.1\|1702369_1702723_-\|ribosome-silencing-factor	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47
NZ_CP029675.1\|WP_000368338.1\|1694669_1696493_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP029675.1\|WP_001802022.1\|1700924_1701611_-\|ComEA-family-DNA-binding-protein	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	1.06297e-33
NZ_CP029675.1\|WP_000108668.1\|1685019_1686366_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
NZ_CP029675.1\|WP_000627144.1\|1691902_1692880_-\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119
NZ_CP029675.1\|WP_000218103.1\|1692979_1694104_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP029675.1\|WP_000725167.1\|1703297_1703867_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.64141e-76
NZ_CP029675.1\|WP_001190120.1\|1686372_1687125_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.90273e-91
NZ_CP029675.1\|WP_001119021.1\|1688068_1689208_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0
NZ_CP029675.1\|WP_001802667.1\|1683623_1684307_-\|hypothetical-protein	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	8.78003e-63

>NZ_CP029675.1|WP_000218103.1|1692979_1694104_-|oxygen-independent-coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>NZ_CP029675.1|WP_000627144.1|1691902_1692880_-|heat-inducible-transcription-repressor-HrcA
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>NZ_CP029675.1|WP_000182211.1|1691244_1691871_-|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>NZ_CP029675.1|WP_000034716.1|1689343_1691176_-|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>NZ_CP029675.1|WP_001119021.1|1688068_1689208_-|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>NZ_CP029675.1|WP_001104607.1|1687126_1688065_-|50S-ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>NZ_CP029675.1|WP_001190120.1|1686372_1687125_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>NZ_CP029675.1|WP_000108668.1|1685019_1686366_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYVSKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>NZ_CP029675.1|WP_000048060.1|1684550_1684727_-|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>NZ_CP029675.1|WP_001802667.1|1683623_1684307_-|hypothetical-protein
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>NZ_CP029675.1|WP_000368338.1|1694669_1696493_-|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>NZ_CP029675.1|WP_001274017.1|1696838_1697090_+|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>NZ_CP029675.1|WP_001282563.1|1697134_1698109_-|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>NZ_CP029675.1|WP_000953309.1|1698165_1700313_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLSTFLFILLLYITYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>NZ_CP029675.1|WP_000439693.1|1700371_1700833_-|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>NZ_CP029675.1|WP_001802022.1|1700924_1701611_-|ComEA-family-DNA-binding-protein
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI
>NZ_CP029675.1|WP_000084830.1|1701650_1702367_-|class-I-SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDTERLFFIAKK
>NZ_CP029675.1|WP_001088020.1|1702369_1702723_-|ribosome-silencing-factor
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>NZ_CP029675.1|WP_001019324.1|1702723_1703308_-|HD-domain-containing-protein
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>NZ_CP029675.1|WP_000725167.1|1703297_1703867_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

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Crispr_ID: NZ_CP029675_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_6

2130454-2130535

Orphan

Consensus_repeat	Method
GGCCCCCACCCCAACTTACATTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_6

>merge|NZ_CP029675|6|2130454-2130535|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCCACCCCAACTTGCATTGT

>NZ_CP029675|6|6|2130454-2130535|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGG
GGCCCCCACCCCAACTTGCATTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000846280.1\|2139500_2140079_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000595392.1\|2126637_2127654_-\|bi-component-leukocidin-LukGH-subunit-G	unknown	unknown	gnl\|CDD\|369625
NZ_CP029675.1\|WP_000771368.1\|2138686_2139214_-\|spore-coat-protein	unknown	unknown	gnl\|CDD\|227864
NZ_CP029675.1\|WP_001035616.1\|2135478_2136039_+\|DUF4888-domain-containing-protein	unknown	unknown	gnl\|CDD\|294014
NZ_CP029675.1\|WP_000206624.1\|2129166_2130369_+\|ArgE/DapE-family-deacylase	unknown	unknown	gnl\|CDD\|181490
NZ_CP029675.1\|WP_000278088.1\|2133891_2134692_-\|staphylococcal-enterotoxin-type-C3	unknown	unknown	gnl\|CDD\|280949
NZ_CP029675.1\|WP_000825947.1\|2123958_2124423_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236154
NZ_CP029675.1\|WP_001293088.1\|2137776_2138346_-\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|226251
NZ_CP029675.1\|WP_000358774.1\|2138342_2138684_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000435341.1\|2121366_2121627_-\|transcriptional-regulator	unknown	unknown	unknown
NZ_CP029675.1\|WP_001035599.1\|2136917_2137622_+\|toxic-shock-syndrome-toxin-TSST-1	unknown	unknown	gnl\|CDD\|171853
NZ_CP029675.1\|WP_000705248.1\|2123676_2123859_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001083967.1\|2122046_2122763_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225484
NZ_CP029675.1\|WP_000448770.1\|2139264_2139483_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374753
NZ_CP029675.1\|WP_000791413.1\|2127675_2128731_-\|bi-component-leukocidin-LukGH-subunit-H	unknown	unknown	gnl\|CDD\|369625
NZ_CP029675.1\|WP_000746599.1\|2133000_2133723_+\|exotoxin	unknown	unknown	gnl\|CDD\|280949
NZ_CP029675.1\|WP_000639927.1\|2121640_2121883_-\|DUF739-family-protein	unknown	unknown	gnl\|CDD\|283090
NZ_CP029675.1\|WP_001045082.1\|2130676_2131984_+\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|273349
NZ_CP029675.1\|WP_000857191.1\|2124481_2125519_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP029675.1\|WP_000804507.1\|2122774_2123632_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|214906

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000595392.1\|2126637_2127654_-\|bi-component-leukocidin-LukGH-subunit-G	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.05827e-99
NZ_CP029675.1\|WP_000771368.1\|2138686_2139214_-\|spore-coat-protein	gnl\|CDD\|227864	COG5577, COG5577, Spore coat protein [Cell envelope biogenesis, outer membrane].	5.42048e-39
NZ_CP029675.1\|WP_001035616.1\|2135478_2136039_+\|DUF4888-domain-containing-protein	gnl\|CDD\|294014	cd15783, SA1633_like, Uncharacterized protein family conserved in Staphylococci. Some proteins in this family have been described as putative beta-lactamases. They are structurally similar to the C-terminal beta-grasp domains of Staphylococcal and Streptococcal superantigens.	1.47157e-43
NZ_CP029675.1\|WP_000206624.1\|2129166_2130369_+\|ArgE/DapE-family-deacylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NZ_CP029675.1\|WP_000825947.1\|2123958_2124423_+\|hypothetical-protein	gnl\|CDD\|236154	PRK08119, PRK08119, flagellar motor switch protein; Validated.	0.00756653
NZ_CP029675.1\|WP_001293088.1\|2137776_2138346_-\|terminase-small-subunit	gnl\|CDD\|226251	COG3728, XtmA, Phage terminase, small subunit [DNA replication, recombination, and repair].	4.68659e-70
NZ_CP029675.1\|WP_001035599.1\|2136917_2137622_+\|toxic-shock-syndrome-toxin-TSST-1	gnl\|CDD\|171853	PRK13038, PRK13038, superantigen-like protein; Reviewed.	1.96896e-09
NZ_CP029675.1\|WP_000278088.1\|2133891_2134692_-\|staphylococcal-enterotoxin-type-C3	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.74895e-25
NZ_CP029675.1\|WP_001083967.1\|2122046_2122763_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	2.44903e-21
NZ_CP029675.1\|WP_000448770.1\|2139264_2139483_-\|hypothetical-protein	gnl\|CDD\|374753	pfam16722, SAPIS-gp6, Pathogenicity island protein gp6 in Staphylococcus. SAPIS-gp6 is a family of proteins produced from the pathogenicity island SAPI1 in pathogenic Staphylococcus aureus. This is a mobile genetic element that carries genes for several superantigen toxins. SAPIS-gp6 is a dimeric protein produced from the pathogenicity island with a helix-loop-helix motif similar to that of bacteriophage scaffolding proteins. It is thought to determine the size of the capsids of distribution of the SAPI1 genome as it acts as an internal scaffolding protein during capsid size determination.	1.38272e-18
NZ_CP029675.1\|WP_000791413.1\|2127675_2128731_-\|bi-component-leukocidin-LukGH-subunit-H	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	3.33169e-77
NZ_CP029675.1\|WP_000746599.1\|2133000_2133723_+\|exotoxin	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	6.68431e-31
NZ_CP029675.1\|WP_000639927.1\|2121640_2121883_-\|DUF739-family-protein	gnl\|CDD\|283090	pfam05339, DUF739, Protein of unknown function (DUF739). This family contains several bacteriophage proteins. Some of the proteins in this family have been labeled putative cro repressor proteins.	5.84085e-08
NZ_CP029675.1\|WP_001045082.1\|2130676_2131984_+\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	1.35788e-81
NZ_CP029675.1\|WP_000857191.1\|2124481_2125519_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.40962e-25
NZ_CP029675.1\|WP_000804507.1\|2122774_2123632_+\|restriction-endonuclease	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	8.51444e-12

>NZ_CP029675.1|WP_000206624.1|2129166_2130369_+|ArgE/DapE-family-deacylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYCLTVNIQISTSTFSLIK
>NZ_CP029675.1|WP_000791413.1|2127675_2128731_-|bi-component-leukocidin-LukGH-subunit-H
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPSILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>NZ_CP029675.1|WP_000595392.1|2126637_2127654_-|bi-component-leukocidin-LukGH-subunit-G
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>NZ_CP029675.1|WP_000857191.1|2124481_2125519_+|site-specific-integrase
MKTRCYDGKKWQYEFKHEGKRYRKKGFRTKREANSAGLDKLNELRSGFNIDNYITLEEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINRQVYQKFINDYSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTNTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEGGSIINLHAINNALKSACRVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM
>NZ_CP029675.1|WP_000825947.1|2123958_2124423_+|hypothetical-protein
MKRLLGLLLVSTLVLSACGNDENQEESKKEVKSKEKKIEKEKENKSKKDKEKEVATQQQPDNQTVEQPQSQEQSVQQPQQQIPQNSVPQQNVQVQQNKKQKVDLNNMPPTDFSTEGMSEQAQKQIEELSMQKDYHGLSQREYNDRVSEIINNDN
>NZ_CP029675.1|WP_000705248.1|2123676_2123859_+|hypothetical-protein
MKITNCKIKRETVIYEVLTSGNQPFTYELPKDLSSHNARKYLEFISQKLDGDKLTKEDSL
>NZ_CP029675.1|WP_000804507.1|2122774_2123632_+|restriction-endonuclease
MKPRKQDEKILSDQYSYFEPIISDSCDIKFDGDKRRIGSIFISHEEICFIRKEEDYIFKISLSDVVDYNTVVTIWKNQASLTLNDNRKITFYFVTNSPLTGFISILKTYMQLSRNKETIIPDDNLLINDDDEQTKVEIFDVVGLNYEGRRKELKKLIKKMKTNDAFFFLYSDLKGNELKEELLYEDKVYEIPDYEVIPGVFLQKEPDNPYDENAIKVMISNEYSEFHVGYVPREYASRLVNYIEDTVSCNAYINGGKYKTLDYLEEKIVTKESDYGLRIHVEYKV
>NZ_CP029675.1|WP_001083967.1|2122046_2122763_+|helix-turn-helix-domain-containing-protein
MNSFKDRLKQIMSERKISQSELSRRTGIGRNSISDYLNGKYEAKQDKVFELAKALNVNEAWLMGFDISKNRKIENNDIASIYSKLTPPRQKNVLNYANEQLDEQNTKGDNIVDINSYKQDRIAVNVNGCVSAGVGERLHGETLFTEMVKAPIPPHDLALKVNGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKEYRDLHFYRNESVRLVGKVIL
>NZ_CP029675.1|WP_000639927.1|2121640_2121883_-|DUF739-family-protein
MIYNFDYSLLYERMAEYRYSQSSLANAIPISRTSINHKLQGKNLFTQWEIKRICELLEIPPTKVGRYFFEQNVQKTVQTS
>NZ_CP029675.1|WP_000435341.1|2121366_2121627_-|transcriptional-regulator
MEQITLTKEECVEQCINKDLKLLDYRVQQILEGVLSESTTYGDARNKLETLKIIAESHFKTEHASVIYKLALKKLDEKINATPIKE
>NZ_CP029675.1|WP_001045082.1|2130676_2131984_+|TrkH-family-potassium-uptake-protein
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKMSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>NZ_CP029675.1|WP_000746599.1|2133000_2133723_+|exotoxin
MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVNLKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDVFGISYKYGSNSRTIYGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQDEFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLKIYKDNKTVDSTQFHLDVEISKR
>NZ_CP029675.1|WP_000278088.1|2133891_2134692_-|staphylococcal-enterotoxin-type-C3
MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG
>NZ_CP029675.1|WP_001035616.1|2135478_2136039_+|DUF4888-domain-containing-protein
MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTDNALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINPQNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGKVGEDKSNVSNRYINPKDINEIQITKK
>NZ_CP029675.1|WP_001035599.1|2136917_2137622_+|toxic-shock-syndrome-toxin-TSST-1
MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEIN
>NZ_CP029675.1|WP_001293088.1|2137776_2138346_-|terminase-small-subunit
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELVEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEDLDKTVQEVSNANPNHTVIVDDIPLED
>NZ_CP029675.1|WP_000358774.1|2138342_2138684_-|hypothetical-protein
MDKKQIKDFVCDYHKRTISDVLIDDEINTDEFFSIGDENSNEWMADDNIDDHIVKNHLEMIVDQVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYETLLDKIVEVIE
>NZ_CP029675.1|WP_000771368.1|2138686_2139214_-|spore-coat-protein
MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNMALLKKVLNHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSYVKVV
>NZ_CP029675.1|WP_000448770.1|2139264_2139483_-|hypothetical-protein
METKYELNNTKKVANAFGLNEADTNLLINAVDLDIKNNMQEISSELQQSEQSKQKQYGTTLQNLAKQNRIIK
>NZ_CP029675.1|WP_000846280.1|2139500_2140079_-|hypothetical-protein
MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR

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Crispr_ID: NZ_CP029675_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_7

2146097-2146185

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_7

>merge|NZ_CP029675|7|2146097-2146185|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>NZ_CP029675|7|7|2146097-2146185|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_001105696.1\|2155285_2155849_+\|accessory-gene-regulator-ArgB-like-protein	unknown	unknown	gnl\|CDD\|226899
NZ_CP029675.1\|WP_001549197.1\|2154915_2155050_-\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP029675.1\|WP_000917289.1\|2149872_2150157_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP029675.1\|WP_000153640.1\|2145860_2146079_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP029675.1\|WP_000846280.1\|2139500_2140079_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001058495.1\|2145193_2145403_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000120296.1\|2151099_2152347_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
NZ_CP029675.1\|WP_000620857.1\|2146251_2146926_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP029675.1\|WP_000867951.1\|2153530_2154316_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP029675.1\|WP_001078344.1\|2144864_2145191_-\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_CP029675.1\|WP_000197635.1\|2150331_2151075_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP029675.1\|WP_000447473.1\|2142207_2143917_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP029675.1\|WP_000240642.1\|2148180_2149797_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP029675.1\|WP_000356942.1\|2141517_2141898_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001047698.1\|2140879_2141521_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374630
NZ_CP029675.1\|WP_000784885.1\|2145395_2145542_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000179343.1\|2146939_2148112_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP029675.1\|WP_001002689.1\|2143930_2144800_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214926
NZ_CP029675.1\|WP_000481967.1\|2145538_2145856_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP029675.1\|WP_000522381.1\|2152543_2153170_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_001105696.1\|2155285_2155849_+\|accessory-gene-regulator-ArgB-like-protein	gnl\|CDD\|226899	COG4512, AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription].	6.65966e-71
NZ_CP029675.1\|WP_001549197.1\|2154915_2155050_-\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NZ_CP029675.1\|WP_000917289.1\|2149872_2150157_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NZ_CP029675.1\|WP_000153640.1\|2145860_2146079_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NZ_CP029675.1\|WP_000179343.1\|2146939_2148112_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.67501e-47
NZ_CP029675.1\|WP_000120296.1\|2151099_2152347_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	8.13501e-10
NZ_CP029675.1\|WP_000620857.1\|2146251_2146926_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NZ_CP029675.1\|WP_001078344.1\|2144864_2145191_-\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.179e-19
NZ_CP029675.1\|WP_000197635.1\|2150331_2151075_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
NZ_CP029675.1\|WP_000447473.1\|2142207_2143917_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
NZ_CP029675.1\|WP_000240642.1\|2148180_2149797_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP029675.1\|WP_001047698.1\|2140879_2141521_-\|hypothetical-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	3.70035e-117
NZ_CP029675.1\|WP_000867951.1\|2153530_2154316_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	5.69545e-126
NZ_CP029675.1\|WP_001002689.1\|2143930_2144800_-\|hypothetical-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	1.21323e-15
NZ_CP029675.1\|WP_000481967.1\|2145538_2145856_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_CP029675.1\|WP_000522381.1\|2152543_2153170_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	8.42197e-117

>NZ_CP029675.1|WP_000153640.1|2145860_2146079_-|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_CP029675.1|WP_000481967.1|2145538_2145856_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_CP029675.1|WP_000784885.1|2145395_2145542_-|hypothetical-protein
MKMYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGGLENE
>NZ_CP029675.1|WP_001058495.1|2145193_2145403_-|hypothetical-protein
MNNEQKEVIEHVVYQLELSVVNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
>NZ_CP029675.1|WP_001078344.1|2144864_2145191_-|DUF1474-family-protein
MNREIKDLFSDLKLLKDSFEDLKDSNGWHFDELYPYEPNHVLNKDELIGEGFSYHERRIHNNQMFDLFHLYIEQFDNIIEKFYEIEKASSENFGEESDDAKNSIKVAE
>NZ_CP029675.1|WP_001002689.1|2143930_2144800_-|hypothetical-protein
MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPEWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGETIKKHRNDVNVIYRDVIVLDYDEINDLKQLHEAISSVLSSVAWYWHTSFSHTTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>NZ_CP029675.1|WP_000447473.1|2142207_2143917_-|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNVKLFSNDKGFQKLIDSFRSKGTLQGYSKKVFAQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSTTYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIVGDGYDSVNYGDVKAVYKHDFLCIKNETVKNKLGHEMQTITGQWDKKGYLIKDKKRIQKQVKHKSQRHLGYAIKKEIIEELGFDFSISHNPYTESY
>NZ_CP029675.1|WP_000356942.1|2141517_2141898_-|hypothetical-protein
MDKEQLKKYIYEYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFIMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>NZ_CP029675.1|WP_001047698.1|2140879_2141521_-|hypothetical-protein
MNLETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMVYVMMNSKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKHLSISDMMASHLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>NZ_CP029675.1|WP_000846280.1|2139500_2140079_-|hypothetical-protein
MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR
>NZ_CP029675.1|WP_000620857.1|2146251_2146926_+|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NZ_CP029675.1|WP_000179343.1|2146939_2148112_+|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAIHHAIERFKNKPIQTIKKHDYQRFVNDISIQYSKNYVDSIVTSTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIHKKFLEKDELFQFLEIAKNHHSPQNSFEVFYTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQYQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTNITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_CP029675.1|WP_000240642.1|2148180_2149797_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_CP029675.1|WP_000917289.1|2149872_2150157_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP029675.1|WP_000197635.1|2150331_2151075_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP029675.1|WP_000120296.1|2151099_2152347_-|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPDKPKPNLDPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP029675.1|WP_000522381.1|2152543_2153170_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSKEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_CP029675.1|WP_000867951.1|2153530_2154316_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP029675.1|WP_001549197.1|2154915_2155050_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NZ_CP029675.1|WP_001105696.1|2155285_2155849_+|accessory-gene-regulator-ArgB-like-protein
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLPIFFPKED

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Crispr_ID: NZ_CP029675_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_8

2275251-2275331

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP029675_8

>merge|NZ_CP029675|8|2275251-2275331|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NZ_CP029675|8|8|2275251-2275331|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000495669.1\|2274142_2275234_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001792784.1\|2276450_2276609_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000370925.1\|2277266_2278124_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP029675.1\|WP_000334463.1\|2279205_2281011_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP029675.1\|WP_001802298.1\|2275666_2275771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000648723.1\|2285842_2286949_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP029675.1\|WP_000808817.1\|2270125_2270356_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001123303.1\|2267210_2267624_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP029675.1\|WP_000927371.1\|2283264_2285397_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP029675.1\|WP_000160304.1\|2265736_2266447_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP029675.1\|WP_000003759.1\|2272577_2272898_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP029675.1\|WP_000019734.1\|2272899_2273877_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP029675.1\|WP_000070866.1\|2266567_2267011_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP029675.1\|WP_001127961.1\|2270386_2271325_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP029675.1\|WP_001292149.1\|2285408_2285843_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP029675.1\|WP_000083807.1\|2281691_2283230_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP029675.1\|WP_000123398.1\|2268080_2269454_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP029675.1\|WP_000908182.1\|2278191_2278974_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP029675.1\|WP_001048266.1\|2287267_2294713_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_CP029675.1\|WP_001024095.1\|2271760_2272426_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000648723.1\|2285842_2286949_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP029675.1\|WP_000370925.1\|2277266_2278124_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NZ_CP029675.1\|WP_000334463.1\|2279205_2281011_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP029675.1\|WP_001123303.1\|2267210_2267624_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP029675.1\|WP_000927371.1\|2283264_2285397_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NZ_CP029675.1\|WP_000160304.1\|2265736_2266447_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP029675.1\|WP_000003759.1\|2272577_2272898_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP029675.1\|WP_000908182.1\|2278191_2278974_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
NZ_CP029675.1\|WP_000070866.1\|2266567_2267011_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP029675.1\|WP_000123398.1\|2268080_2269454_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	4.11455e-06
NZ_CP029675.1\|WP_001292149.1\|2285408_2285843_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP029675.1\|WP_000083807.1\|2281691_2283230_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP029675.1\|WP_001127961.1\|2270386_2271325_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	1.00589e-128
NZ_CP029675.1\|WP_000019734.1\|2272899_2273877_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.49165e-107
NZ_CP029675.1\|WP_001048266.1\|2287267_2294713_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.54008e-108
NZ_CP029675.1\|WP_001024095.1\|2271760_2272426_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47

>NZ_CP029675.1|WP_000495669.1|2274142_2275234_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP029675.1|WP_000019734.1|2272899_2273877_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP029675.1|WP_000003759.1|2272577_2272898_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP029675.1|WP_001024095.1|2271760_2272426_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_CP029675.1|WP_001127961.1|2270386_2271325_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSKDLDSVFEGDFTLMISYV
>NZ_CP029675.1|WP_000808817.1|2270125_2270356_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP029675.1|WP_000123398.1|2268080_2269454_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP029675.1|WP_001123303.1|2267210_2267624_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP029675.1|WP_000070866.1|2266567_2267011_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP029675.1|WP_000160304.1|2265736_2266447_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP029675.1|WP_001802298.1|2275666_2275771_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP029675.1|WP_001792784.1|2276450_2276609_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP029675.1|WP_000370925.1|2277266_2278124_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP029675.1|WP_000908182.1|2278191_2278974_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP029675.1|WP_000334463.1|2279205_2281011_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP029675.1|WP_000083807.1|2281691_2283230_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP029675.1|WP_000927371.1|2283264_2285397_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP029675.1|WP_001292149.1|2285408_2285843_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP029675.1|WP_000648723.1|2285842_2286949_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP029675.1|WP_001048266.1|2287267_2294713_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGITKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEEKEAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDHSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQKSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: NZ_CP029675_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_9

2287572-2287657

Orphan

Consensus_repeat	Method
CCAACTGATTTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_9

>merge|NZ_CP029675|9|2287572-2287657|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGGGCCAACTGATTTTTGCGTATCATTAGT

>NZ_CP029675|9|9|2287572-2287657|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGGG
CCAACTGATTTTTGCGTATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000495669.1\|2274142_2275234_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000370925.1\|2277266_2278124_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP029675.1\|WP_000894032.1\|2296372_2297305_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP029675.1\|WP_000083807.1\|2281691_2283230_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP029675.1\|WP_001802298.1\|2275666_2275771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000521495.1\|2294990_2296346_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP029675.1\|WP_000147095.1\|2312233_2312749_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NZ_CP029675.1\|WP_000927371.1\|2283264_2285397_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP029675.1\|WP_000636857.1\|2308428_2308902_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP029675.1\|WP_001292149.1\|2285408_2285843_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP029675.1\|WP_000908182.1\|2278191_2278974_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP029675.1\|WP_001792784.1\|2276450_2276609_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001141007.1\|2306663_2308106_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_CP029675.1\|WP_000047255.1\|2310300_2310984_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP029675.1\|WP_000347896.1\|2297306_2298116_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP029675.1\|WP_000334463.1\|2279205_2281011_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP029675.1\|WP_000884735.1\|2311002_2312190_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_CP029675.1\|WP_000648723.1\|2285842_2286949_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP029675.1\|WP_000958531.1\|2305451_2306516_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP029675.1\|WP_000167867.1\|2298304_2299213_-\|arginase	unknown	unknown	gnl\|CDD\|212515

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000370925.1\|2277266_2278124_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NZ_CP029675.1\|WP_000636857.1\|2308428_2308902_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NZ_CP029675.1\|WP_000083807.1\|2281691_2283230_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP029675.1\|WP_000167867.1\|2298304_2299213_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	9.8301e-146
NZ_CP029675.1\|WP_000521495.1\|2294990_2296346_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP029675.1\|WP_000147095.1\|2312233_2312749_-\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	4.3406e-25
NZ_CP029675.1\|WP_000927371.1\|2283264_2285397_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NZ_CP029675.1\|WP_000648723.1\|2285842_2286949_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP029675.1\|WP_000884735.1\|2311002_2312190_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
NZ_CP029675.1\|WP_001292149.1\|2285408_2285843_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP029675.1\|WP_000347896.1\|2297306_2298116_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP029675.1\|WP_001141007.1\|2306663_2308106_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.85929e-81
NZ_CP029675.1\|WP_000047255.1\|2310300_2310984_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_CP029675.1\|WP_000334463.1\|2279205_2281011_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP029675.1\|WP_000908182.1\|2278191_2278974_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
NZ_CP029675.1\|WP_000894032.1\|2296372_2297305_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NZ_CP029675.1\|WP_000958531.1\|2305451_2306516_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115

>NZ_CP029675.1|WP_000648723.1|2285842_2286949_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP029675.1|WP_001292149.1|2285408_2285843_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP029675.1|WP_000927371.1|2283264_2285397_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP029675.1|WP_000083807.1|2281691_2283230_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP029675.1|WP_000334463.1|2279205_2281011_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP029675.1|WP_000908182.1|2278191_2278974_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP029675.1|WP_000370925.1|2277266_2278124_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP029675.1|WP_001792784.1|2276450_2276609_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP029675.1|WP_001802298.1|2275666_2275771_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP029675.1|WP_000495669.1|2274142_2275234_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP029675.1|WP_000521495.1|2294990_2296346_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP029675.1|WP_000894032.1|2296372_2297305_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_CP029675.1|WP_000347896.1|2297306_2298116_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP029675.1|WP_000167867.1|2298304_2299213_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_CP029675.1|WP_000958531.1|2305451_2306516_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP029675.1|WP_001141007.1|2306663_2308106_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNVLLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_CP029675.1|WP_000636857.1|2308428_2308902_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP029675.1|WP_000047255.1|2310300_2310984_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP029675.1|WP_000884735.1|2311002_2312190_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
>NZ_CP029675.1|WP_000147095.1|2312233_2312749_-|metal-dependent-hydrolase
MTGKTHASCGMLVGALTTQYFQTDIFSSVTVIILATLASLLPDICHTQSKIGRRFKVISFFVRLIFGHRTFTHSILFIAIIAFLLQIIQTPNYYMAAIIIGLVSHVILDMITPRGVKLFYPLPFNVKTPIQFKTGGLVDLSLATALMVGTVYVLFQPFINDIISNWNTKFL

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Crispr_ID: NZ_CP029675_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029675_10

2395329-2395409

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029675_10

>merge|NZ_CP029675|10|2395329-2395409|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTG

>NZ_CP029675|10|10|2395329-2395409|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTCTGTCAGCT
TCTGTGTTGGGGCCCCGCCAACTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029675.1\|WP_000134526.1\|2399703_2400198_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP029675.1\|WP_000051210.1\|2385862_2386027_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001838204.1\|2395552_2396575_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP029675.1\|WP_001549681.1\|2391710_2391962_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000066900.1\|2394625_2394976_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP029675.1\|WP_001161085.1\|2386271_2386589_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_001792132.1\|2395101_2395287_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029675.1\|WP_000808495.1\|2397439_2397886_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP029675.1\|WP_000259717.1\|2398381_2399641_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP029675.1\|WP_000184404.1\|2393312_2394524_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP029675.1\|WP_000592307.1\|2386772_2389940_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP029675.1\|WP_000600967.1\|2391953_2392718_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP029675.1\|WP_000866971.1\|2397200_2397434_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP029675.1\|WP_000643986.1\|2396594_2397194_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP029675.1\|WP_000602950.1\|2397899_2398385_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP029675.1\|WP_110232077.1\|2390056_2391322_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP029675.1\|WP_000503822.1\|2400199_2400706_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP029675.1\|WP_000076930.1\|2400736_2401741_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP029675.1\|WP_000951058.1\|2392879_2393320_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP029675.1\|WP_000913024.1\|2401910_2402516_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628

Protein	Function_ID	Function_description	E-value
NZ_CP029675.1\|WP_000134526.1\|2399703_2400198_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.93711e-97
NZ_CP029675.1\|WP_001838204.1\|2395552_2396575_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.12237e-165
NZ_CP029675.1\|WP_000600967.1\|2391953_2392718_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP029675.1\|WP_000066900.1\|2394625_2394976_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP029675.1\|WP_000808495.1\|2397439_2397886_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	6.99133e-58
NZ_CP029675.1\|WP_000643986.1\|2396594_2397194_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	2.15389e-66
NZ_CP029675.1\|WP_000259717.1\|2398381_2399641_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	4.50966e-159
NZ_CP029675.1\|WP_000602950.1\|2397899_2398385_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	9.59347e-51
NZ_CP029675.1\|WP_000592307.1\|2386772_2389940_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP029675.1\|WP_000184404.1\|2393312_2394524_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.92881e-73
NZ_CP029675.1\|WP_000866971.1\|2397200_2397434_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP029675.1\|WP_000076930.1\|2400736_2401741_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	6.83722e-133
NZ_CP029675.1\|WP_110232077.1\|2390056_2391322_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	2.85443e-143
NZ_CP029675.1\|WP_000503822.1\|2400199_2400706_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.42221e-64
NZ_CP029675.1\|WP_000951058.1\|2392879_2393320_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP029675.1\|WP_000913024.1\|2401910_2402516_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.78595e-116

>NZ_CP029675.1|WP_001792132.1|2395101_2395287_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDLECDINVKEPLKINYVVIFGSGTEITFSQNLFR
>NZ_CP029675.1|WP_000066900.1|2394625_2394976_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP029675.1|WP_000184404.1|2393312_2394524_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETDVINKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP029675.1|WP_000951058.1|2392879_2393320_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP029675.1|WP_000600967.1|2391953_2392718_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP029675.1|WP_001549681.1|2391710_2391962_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP029675.1|WP_110232077.1|2390056_2391322_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLSSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP029675.1|WP_000592307.1|2386772_2389940_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHVDGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP029675.1|WP_001161085.1|2386271_2386589_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP029675.1|WP_000051210.1|2385862_2386027_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP029675.1|WP_001838204.1|2395552_2396575_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQELYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP029675.1|WP_000643986.1|2396594_2397194_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP029675.1|WP_000866971.1|2397200_2397434_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP029675.1|WP_000808495.1|2397439_2397886_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP029675.1|WP_000602950.1|2397899_2398385_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKTHGYTVATIKHHGHAKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP029675.1|WP_000259717.1|2398381_2399641_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP029675.1|WP_000134526.1|2399703_2400198_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NZ_CP029675.1|WP_000503822.1|2400199_2400706_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFVTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP029675.1|WP_000076930.1|2400736_2401741_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP029675.1|WP_000913024.1|2401910_2402516_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP029675_1	1.1\|187896\|33\|NZ_CP029675\|CRISPRCasFinder	187896-187928	33	NZ_CP029675.1	1424572-1424604	0	1.0
NZ_CP029675_3	3.1\|841801\|31\|NZ_CP029675\|CRISPRCasFinder	841801-841831	31	NZ_CP029675.1	311066-311096	0	1.0
NZ_CP029675_6	6.1\|2130478\|34\|NZ_CP029675\|CRISPRCasFinder	2130478-2130511	34	NZ_CP029675.1	841776-841809	0	1.0
NZ_CP029675_6	6.1\|2130478\|34\|NZ_CP029675\|CRISPRCasFinder	2130478-2130511	34	NZ_CP029675.1	1212836-1212869	0	1.0
NZ_CP029675_3	3.1\|841801\|31\|NZ_CP029675\|CRISPRCasFinder	841801-841831	31	NZ_CP029675.1	311011-311041	1	0.968
NZ_CP029675_3	3.1\|841801\|31\|NZ_CP029675\|CRISPRCasFinder	841801-841831	31	NZ_CP029675.1	1728895-1728925	1	0.968
NZ_CP029675_4	4.1\|905279\|34\|NZ_CP029675\|CRISPRCasFinder	905279-905312	34	NZ_CP029675.1	1424571-1424604	1	0.971
NZ_CP029675_5	5.1\|1694439\|33\|NZ_CP029675\|CRISPRCasFinder	1694439-1694471	33	NZ_CP029675.1	847335-847367	1	0.97
NZ_CP029675_5	5.1\|1694439\|33\|NZ_CP029675\|CRISPRCasFinder	1694439-1694471	33	NZ_CP029675.1	847394-847426	1	0.97
NZ_CP029675_5	5.1\|1694439\|33\|NZ_CP029675\|CRISPRCasFinder	1694439-1694471	33	NZ_CP029675.1	1424572-1424604	1	0.97
NZ_CP029675_6	6.1\|2130478\|34\|NZ_CP029675\|CRISPRCasFinder	2130478-2130511	34	NZ_CP029675.1	1822650-1822683	1	0.971
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	854579-854609	1	0.968
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	854635-854665	1	0.968
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	854691-854721	1	0.968
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	854747-854777	1	0.968
NZ_CP029675_1	1.1\|187896\|33\|NZ_CP029675\|CRISPRCasFinder	187896-187928	33	NZ_CP029675.1	847335-847367	2	0.939
NZ_CP029675_1	1.1\|187896\|33\|NZ_CP029675\|CRISPRCasFinder	187896-187928	33	NZ_CP029675.1	847394-847426	2	0.939
NZ_CP029675_1	1.1\|187896\|33\|NZ_CP029675\|CRISPRCasFinder	187896-187928	33	NZ_CP029675.1	1512920-1512952	2	0.939
NZ_CP029675_6	6.1\|2130478\|34\|NZ_CP029675\|CRISPRCasFinder	2130478-2130511	34	NZ_CP029675.1	1428945-1428978	2	0.941
NZ_CP029675_6	6.1\|2130478\|34\|NZ_CP029675\|CRISPRCasFinder	2130478-2130511	34	NZ_CP029675.1	2837211-2837244	2	0.941
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	89385-89415	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	387398-387428	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	675477-675507	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	854803-854833	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	905591-905621	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	1115845-1115875	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	1218432-1218462	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	1424530-1424560	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	1512964-1512994	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	1709077-1709107	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	2027945-2027975	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	2384553-2384583	2	0.935
NZ_CP029675_10	10.1\|2395354\|31\|NZ_CP029675\|CRISPRCasFinder	2395354-2395384	31	NZ_CP029675.1	2561580-2561610	2	0.935

1. spacer 1.1|187896|33|NZ_CP029675|CRISPRCasFinder matches to position: 1424572-1424604, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

2. spacer 3.1|841801|31|NZ_CP029675|CRISPRCasFinder matches to position: 311066-311096, mismatch: 0, identity: 1.0

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattgcc	Protospacer
*******************************

3. spacer 6.1|2130478|34|NZ_CP029675|CRISPRCasFinder matches to position: 841776-841809, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

4. spacer 6.1|2130478|34|NZ_CP029675|CRISPRCasFinder matches to position: 1212836-1212869, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

5. spacer 3.1|841801|31|NZ_CP029675|CRISPRCasFinder matches to position: 311011-311041, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattacc	Protospacer
****************************.**

6. spacer 3.1|841801|31|NZ_CP029675|CRISPRCasFinder matches to position: 1728895-1728925, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttccattgcc	Protospacer
*********************** *******

7. spacer 4.1|905279|34|NZ_CP029675|CRISPRCasFinder matches to position: 1424571-1424604, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

8. spacer 5.1|1694439|33|NZ_CP029675|CRISPRCasFinder matches to position: 847335-847367, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attggaaatccaatttctctgtgttggggccca	Protospacer
*****.***************************

9. spacer 5.1|1694439|33|NZ_CP029675|CRISPRCasFinder matches to position: 847394-847426, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attggaaatccaatttctctgtgttggggccca	Protospacer
*****.***************************

10. spacer 5.1|1694439|33|NZ_CP029675|CRISPRCasFinder matches to position: 1424572-1424604, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

11. spacer 6.1|2130478|34|NZ_CP029675|CRISPRCasFinder matches to position: 1822650-1822683, mismatch: 1, identity: 0.971

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttgtgttgg	Protospacer
*************************.********

12. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 854579-854609, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

13. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 854635-854665, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

14. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 854691-854721, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

15. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 854747-854777, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

16. spacer 1.1|187896|33|NZ_CP029675|CRISPRCasFinder matches to position: 847335-847367, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacacagagaaattggatttccaat	Protospacer
************ **************.*****

17. spacer 1.1|187896|33|NZ_CP029675|CRISPRCasFinder matches to position: 847394-847426, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacacagagaaattggatttccaat	Protospacer
************ **************.*****

18. spacer 1.1|187896|33|NZ_CP029675|CRISPRCasFinder matches to position: 1512920-1512952, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tggaccccaacaaagagaaattgtattcccaat	Protospacer
***.******************* *********

19. spacer 6.1|2130478|34|NZ_CP029675|CRISPRCasFinder matches to position: 1428945-1428978, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtggaatttcttatcgaaattctctgtgttgg	Protospacer
****.********* *******************

20. spacer 6.1|2130478|34|NZ_CP029675|CRISPRCasFinder matches to position: 2837211-2837244, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttttgttgg	Protospacer
*************************.* ******

21. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 89385-89415, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

22. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 387398-387428, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

23. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 675477-675507, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

24. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 854803-854833, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

25. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 905591-905621, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

26. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 1115845-1115875, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

27. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 1218432-1218462, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

28. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 1424530-1424560, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

29. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 1512964-1512994, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

30. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 1709077-1709107, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

31. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 2027945-2027975, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

32. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 2384553-2384583, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

33. spacer 10.1|2395354|31|NZ_CP029675|CRISPRCasFinder matches to position: 2561580-2561610, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP029675_9	9.1\|2287598\|34\|NZ_CP029675\|CRISPRCasFinder	2287598-2287631	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
NZ_CP029675_9	9.1\|2287598\|34\|NZ_CP029675\|CRISPRCasFinder	2287598-2287631	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 9.1|2287598|34|NZ_CP029675|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

2. spacer 9.1|2287598|34|NZ_CP029675|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

432453 : 457397

Streptococcus_phage(78.95%)

integrase

attL 428361:428375|attR 444289:444303

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
428361:428375	attL	NA	NA	NA	NA
WP_000264071.1\|432453_433920_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
WP_000424963.1\|433944_435486_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000237797.1\|435553_436747_-\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	8.3e-44	34.2
WP_000633907.1\|436773_436974_-	DUF3173 family protein	NA	NA	NA	NA
WP_000845143.1\|437471_437702_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	1.0e-27	78.9
WP_000804879.1\|437698_438121_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	7.5e-48	68.6
WP_001227350.1\|438651_439005_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	2.2e-53	89.7
WP_000691737.1\|439347_441267_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.2
WP_001791010.1\|441282_441399_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000584387.1\|441643_442573_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
WP_000768373.1\|442589_443612_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	2.4e-132	75.5
WP_000192393.1\|443608_445636_-	membrane protein	A0A1S5SF30	Streptococcus_phage	5.1e-195	65.3
444289:444303	attR	NA	NA	NA	NA
WP_000331165.1\|445632_448086_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	78.9
WP_000723887.1\|448069_448465_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	5.9e-47	72.6
WP_000248477.1\|448536_449175_-	hypothetical protein	NA	NA	NA	NA
WP_000870467.1\|449230_449725_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	2.8e-54	63.4
WP_000675717.1\|449791_450571_-	abortive infection family protein	NA	NA	NA	NA
WP_001009054.1\|450612_450834_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
WP_000055376.1\|450830_451121_-	hypothetical protein	NA	NA	NA	NA
WP_000426689.1\|451117_452302_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	6.3e-161	68.1
WP_001130244.1\|452483_453887_-	DUF87 domain-containing protein	A0A1S5SFB5	Streptococcus_phage	2.2e-176	66.5
WP_000185761.1\|453908_454682_-	hypothetical protein	NA	NA	NA	NA
WP_001234191.1\|454691_455069_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	9.6e-47	76.4
WP_000421279.1\|455089_455404_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	1.2e-42	77.7
WP_000181735.1\|455603_457397_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	6.9e-26	23.8

DBSCAN-SWA_2

798797 : 813382

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|798797_799856_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197262.1\|800194_800737_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429006.1\|801559_802477_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_031760357.1\|802567_802669_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|802746_804252_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|804592_805093_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068501.1\|805112_805979_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|806779_807178_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855514.1\|807140_809246_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|809363_810335_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|810515_810671_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|810709_811681_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|811667_812624_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1\|812620_813382_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

864517 : 879328

Staphylococcus_phage(73.33%)

integrase,terminase

attL 864185:864200|attR 870607:870622

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
864185:864200	attL	NA	NA	NA	NA
WP_001050048.1\|864517_866890_+	ribonuclease R	Q0GXV6	Lactococcus_phage	4.3e-92	38.8
WP_001085183.1\|866911_867376_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.6e-80	98.7
WP_000121223.1\|867938_869045_-\|integrase	site-specific integrase	H0UST3	Bacillus_phage	5.9e-76	44.2
WP_072474260.1\|869050_869698_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001060953.1\|869855_870062_+	hypothetical protein	NA	NA	NA	NA
WP_000164237.1\|870097_870325_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000784893.1\|870321_870468_+	hypothetical protein	NA	NA	NA	NA
WP_001058487.1\|870460_870670_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	2.2e-29	92.8
870607:870622	attR	NA	NA	NA	NA
WP_001103933.1\|870672_870990_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.2e-18	48.1
WP_001002695.1\|871056_871926_+	hypothetical protein	A0A1W6JQL5	Staphylococcus_phage	3.2e-162	96.9
WP_001668899.1\|871942_873412_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	3.4e-289	99.6
WP_001039169.1\|873697_874060_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	5.8e-65	98.3
WP_000998179.1\|874061_874346_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.2e-49	100.0
WP_110232067.1\|874342_874984_+	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	1.2e-110	92.5
WP_001190615.1\|875432_875774_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
WP_000846280.1\|875785_876364_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
WP_000358774.1\|877175_877517_+	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.4e-57	99.1
WP_001293076.1\|877513_878083_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	9.3e-102	98.9
WP_000801979.1\|878359_879328_+	Abi family protein	A0A0H4U080	Erysipelothrix_phage	5.9e-24	27.3

DBSCAN-SWA_4

913657 : 959666

Staphylococcus_phage(78.57%)

plate,terminase,portal,integrase,head,tail,holin,capsid

attL 915478:915494|attR 924478:924494

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001006450.1\|913657_914908_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.8
WP_001010508.1\|914897_915362_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
915478:915494	attL	NA	NA	NA	NA
WP_001074405.1\|915512_916910_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_001145728.1\|916977_918027_-\|integrase	site-specific integrase	A1KWY3	Staphylococcus_virus	1.6e-203	100.0
WP_000337826.1\|918138_918318_+	hypothetical protein	A0EWN7	Staphylococcus_virus	8.3e-25	100.0
WP_000392186.1\|918297_919230_-	hypothetical protein	A0EWN8	Staphylococcus_virus	3.9e-174	100.0
WP_000524998.1\|919261_919726_-	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	3.6e-80	94.1
WP_000429766.1\|919738_920068_-	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
WP_001115060.1\|920228_920420_+	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
WP_000939498.1\|920508_920652_+	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_000642492.1\|920641_920851_-	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_001148557.1\|920907_921687_+	phage antirepressor KilAC domain-containing protein	M1RZB2	Staphylococcus_phage	4.1e-132	92.6
WP_000187184.1\|921687_921912_+	hypothetical protein	A0A0F6N4M2	Staphylococcus_phage	3.2e-34	100.0
WP_000939498.1\|921951_922095_+	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_001838167.1\|922116_922764_-	hypothetical protein	S4V9K2	Staphylococcus_phage	2.0e-113	100.0
WP_000977378.1\|922834_923056_+	hypothetical protein	E0Y3P2	Staphylococcus_virus	1.5e-31	100.0
WP_000066007.1\|923048_923210_+	DUF1270 domain-containing protein	A0A0E3XBK7	Staphylococcus_phage	4.3e-20	96.2
WP_000165363.1\|923302_923605_+	DUF2482 family protein	A0A0F6N3N3	Staphylococcus_phage	1.4e-48	100.0
WP_000291068.1\|923609_923870_+	DUF1108 family protein	C8CGY6	Staphylococcus_phage	8.9e-44	100.0
WP_000815401.1\|923879_924101_+	DUF2483 family protein	A7TWM6	Staphylococcus_phage	3.2e-34	100.0
WP_000934774.1\|924717_925143_+	single-stranded DNA-binding protein	B7T0A5	Staphylococcus_virus	2.1e-58	88.7
924478:924494	attR	NA	NA	NA	NA
WP_001004505.1\|925153_925705_+	HNH endonuclease	A0A2H4PQR4	Staphylococcus_phage	5.1e-105	98.9
WP_001121803.1\|925705_926380_+	hypothetical protein	R4IH15	Staphylococcus_phage	1.5e-127	97.8
WP_000414755.1\|926519_926801_-	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
WP_000132051.1\|926865_927597_+	helix-turn-helix domain-containing protein	A0A1J0MGB2	Staphylococcus_phage	9.8e-80	78.8
WP_000443353.1\|927609_928395_+	ATP-binding protein	A0A0H4J332	Staphylococcus_phage	1.9e-145	100.0
WP_000628836.1\|928391_928550_+	hypothetical protein	A0A2I6PDX0	Staphylococcus_phage	1.1e-20	94.2
WP_001123695.1\|928562_928784_+	DUF3269 family protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
WP_000049784.1\|928793_929198_+	DUF1064 domain-containing protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
WP_001187242.1\|929202_929388_+	DUF3113 family protein	W5R8N4	Staphylococcus_phage	1.4e-27	100.0
WP_001140289.1\|929388_929760_+	hypothetical protein	A7TWN6	Staphylococcus_phage	4.0e-53	95.9
WP_001126846.1\|929760_930009_+	hypothetical protein	S4V683	Staphylococcus_phage	8.8e-41	97.6
WP_001065109.1\|930023_930272_+	DUF1024 family protein	A0A2H4PQK1	Staphylococcus_phage	1.7e-36	93.9
WP_000185680.1\|930264_930801_+	hypothetical protein	A0A1P8L6E0	Staphylococcus_phage	2.1e-95	100.0
WP_000195779.1\|930837_931044_+	DUF1381 domain-containing protein	A0A1W6JPM8	Staphylococcus_phage	4.9e-21	100.0
WP_000132920.1\|931040_931235_+	hypothetical protein	S4SX95	Staphylococcus_phage	7.9e-29	100.0
WP_001072795.1\|931231_931435_+	hypothetical protein	A0A0N9BAX5	Staphylococcus_phage	5.2e-31	100.0
WP_000608273.1\|931427_931664_+	hypothetical protein	S4SWB7	Staphylococcus_phage	1.6e-36	100.0
WP_031885238.1\|931647_932040_+	phage protein	A0A2I6PDC1	Staphylococcus_phage	1.8e-64	99.2
WP_000595245.1\|932039_932213_+	transcriptional activator RinB	S4SVE4	Staphylococcus_phage	1.1e-21	98.2
WP_000990006.1\|932213_932360_+	hypothetical protein	Q4ZDN7	Staphylococcus_virus	1.3e-15	100.0
WP_000058632.1\|932374_932794_+	transcriptional regulator	I1W651	Staphylococcus_phage	8.1e-71	100.0
WP_001838172.1\|932980_933421_+\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	2.4e-73	99.3
WP_000169948.1\|933407_934685_+\|terminase	PBSX family phage terminase large subunit	A0EWS5	Staphylococcus_virus	5.1e-249	99.8
WP_000921892.1\|934695_936231_+\|portal	phage portal protein	Q4ZDV9	Staphylococcus_virus	9.3e-290	99.4
WP_001133043.1\|936237_937233_+\|capsid	minor capsid protein	E0Y3K7	Staphylococcus_virus	3.4e-184	100.0
WP_000072207.1\|937305_937476_+	hypothetical protein	Q4ZDF2	Staphylococcus_virus	3.3e-23	100.0
WP_000354307.1\|937610_938225_+	DUF4355 domain-containing protein	A0EWS9	Staphylococcus_virus	4.9e-40	100.0
WP_001114085.1\|939233_939521_+	hypothetical protein	S4V6D9	Staphylococcus_phage	4.7e-46	100.0
WP_000208960.1\|939529_939862_+\|head,tail	phage head-tail connector protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
WP_001268314.1\|939858_940161_+	hypothetical protein	S4V7K8	Staphylococcus_phage	1.1e-50	100.0
WP_001017814.1\|940160_940508_+	HK97 gp10 family phage protein	S4V987	Staphylococcus_phage	3.1e-60	100.0
WP_000188649.1\|940519_940903_+	hypothetical protein	A0A0F6N3L1	Staphylococcus_phage	1.5e-68	100.0
WP_000002577.1\|940921_941503_+\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	4.9e-106	100.0
WP_001100167.1\|941564_941930_+	hypothetical protein	S4V9M6	Staphylococcus_phage	2.8e-59	100.0
WP_000105584.1\|941959_942304_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
WP_000141453.1\|942320_945785_+	hypothetical protein	S4V989	Staphylococcus_phage	5.8e-271	100.0
WP_000350686.1\|945797_946745_+\|tail	phage tail family protein	S4V688	Staphylococcus_phage	3.6e-183	100.0
WP_000156404.1\|946753_948655_+	peptidase	Q4ZDD8	Staphylococcus_virus	0.0e+00	100.0
WP_000369014.1\|948669_950580_+	hypothetical protein	A1KX41	Staphylococcus_virus	0.0e+00	99.8
WP_000259629.1\|950579_952403_+\|plate	BppU family phage baseplate upper protein	W5R8J5	Staphylococcus_phage	7.4e-294	99.2
WP_000705911.1\|952402_952780_+	DUF2977 domain-containing protein	Q9FZY7	Staphylococcus_virus	3.4e-60	99.2
WP_000782200.1\|952783_952957_+	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
WP_000466784.1\|952997_953297_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000524006.1\|953433_955332_+	CHAP domain-containing protein	Q8SDT1	Staphylococcus_phage	0.0e+00	99.8
WP_000276646.1\|955344_956583_+\|plate	BppU family phage baseplate upper protein	A0A0F6N3G7	Staphylococcus_phage	2.7e-207	98.1
WP_000398870.1\|956588_956984_+	hypothetical protein	A0A0E3XBL9	Staphylococcus_phage	1.4e-67	97.7
WP_000354127.1\|957039_957477_+\|holin	phage holin	Q8SDS8	Staphylococcus_phage	6.9e-73	99.3
WP_001148136.1\|957457_958903_+	CHAP domain-containing protein	Q08JW9	Staphylococcus_phage	1.8e-295	99.8
WP_001788502.1\|959145_959298_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	3.1e-20	100.0
WP_001838173.1\|959368_959479_+	hypothetical protein	W5R8J7	Staphylococcus_phage	4.9e-12	97.2
WP_000382163.1\|959465_959666_+	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0

DBSCAN-SWA_5

1117355 : 1125828

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1117355_1117838_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010413.1\|1117824_1118949_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1118952_1119657_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1119656_1119920_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666806.1\|1119921_1120593_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032740.1\|1120585_1122775_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000483720.1\|1122753_1124238_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000030811.1\|1124230_1125259_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000238669.1\|1125261_1125828_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_6

1744083 : 1753126

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1744083_1744602_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000595011.1\|1744623_1746897_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
WP_000749795.1\|1747099_1749379_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1749653_1749914_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1749932_1751072_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1751094_1752120_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1752121_1753126_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_7

1876883 : 1948373

Staphylococcus_phage(95.56%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001266161.1\|1876883_1877528_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_000434765.1\|1877542_1878334_-	phosphotransferase family protein	NA	NA	NA	NA
WP_000411084.1\|1878883_1879732_-	D-amino-acid transaminase	NA	NA	NA	NA
WP_000265417.1\|1879735_1881145_-	Mn(2+)-dependent dipeptidase Sapep	NA	NA	NA	NA
WP_001051856.1\|1881702_1882125_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_001217125.1\|1882141_1882837_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000004335.1\|1882833_1884495_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_000836461.1\|1893052_1893364_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
WP_001108730.1\|1893385_1895800_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025067.1\|1896090_1897272_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
WP_000526539.1\|1897381_1898335_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1898331_1898895_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1899017_1899419_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1899988_1900816_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1900818_1900938_-	hypothetical protein	NA	NA	NA	NA
WP_001196362.1\|1901049_1902051_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
WP_001008549.1\|1902172_1902637_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159037.1\|1902649_1903831_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
WP_000493887.1\|1903841_1904474_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
WP_000384185.1\|1904480_1905512_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
WP_001261668.1\|1906004_1907507_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000221177.1\|1908029_1908344_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_000989121.1\|1908343_1909636_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_001032830.1\|1909722_1910577_-	autolysin	Q4ZCC7	Staphylococcus_virus	1.3e-38	38.6
WP_000384171.1\|1910852_1911077_-	hypothetical protein	NA	NA	NA	NA
WP_000671057.1\|1911275_1911746_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	8.8e-82	98.1
WP_001153742.1\|1911858_1912302_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1912288_1912732_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168903.1\|1913027_1913663_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096495.1\|1914102_1914816_-	transaldolase	M1PR54	Cyanophage	9.4e-19	35.3
WP_000091442.1\|1915075_1915378_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1915633_1915999_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623470.1\|1915995_1916349_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
WP_000453306.1\|1918345_1919179_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
WP_000366163.1\|1919390_1920299_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933820.1\|1920420_1921617_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
WP_000109906.1\|1921988_1923581_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_001822900.1\|1923958_1924705_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000672013.1\|1924709_1925183_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1\|1925248_1925506_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778528.1\|1925502_1926504_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.3e-185	97.3
WP_000348364.1\|1926508_1927987_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.8e-283	97.6
WP_012840523.1\|1928145_1928601_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
WP_001795210.1\|1928903_1929554_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.9e-51	94.0
WP_000070642.1\|1929634_1930630_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
WP_000669024.1\|1930704_1931331_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
WP_000627540.1\|1931371_1931713_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
WP_000414216.1\|1931813_1932386_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
WP_001801861.1\|1933740_1933836_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001792025.1\|1933958_1934060_+	hypothetical protein	NA	NA	NA	NA
WP_000072626.1\|1935135_1936365_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	6.8e-134	64.7
WP_001793440.1\|1936357_1938097_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
WP_001791797.1\|1938077_1938212_-	hypothetical protein	NA	NA	NA	NA
WP_001038752.1\|1938274_1938994_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.9e-131	99.6
WP_011447030.1\|1939095_1939203_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1939151_1939871_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038872.1\|1939991_1940711_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_001039454.1\|1940768_1941491_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
WP_001039427.1\|1941615_1942323_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
WP_001092780.1\|1943285_1943867_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8
WP_000469591.1\|1944339_1944558_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	2.0e-25	80.6
WP_000550252.1\|1944813_1945287_+	hypothetical protein	NA	NA	NA	NA
WP_000543854.1\|1945291_1946083_+	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000782463.1\|1946452_1947436_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
WP_000473596.1\|1947437_1948373_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0

DBSCAN-SWA_8

2042190 : 2150157

132

Staphylococcus_phage(83.16%)

tRNA,terminase,portal,protease,integrase,head,tail,holin,capsid,coat

attL 2038627:2038651|attR 2153349:2153373

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2038627:2038651	attL	NA	NA	NA	NA
WP_000170162.1\|2042190_2042493_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957020.1\|2042859_2044398_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831700.1\|2044486_2045686_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774556.1\|2045698_2047702_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	1.2e-114	36.2
WP_000992924.1\|2047705_2049898_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272054.1\|2049894_2050587_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2050758_2051061_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2051169_2052465_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827746.1\|2053324_2054491_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434933.1\|2054521_2054848_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1\|2055139_2055313_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2055293_2055896_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1\|2056166_2056988_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284436.1\|2056980_2058450_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	5.9e-108	45.1
WP_110232074.1\|2058633_2059710_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177828.1\|2059729_2060524_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2060595_2060703_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1\|2060713_2062276_-	SLC13 family permease	NA	NA	NA	NA
WP_000275727.1\|2062480_2063578_-	pectate lyase	U5PWM6	Bacillus_phage	3.3e-47	34.6
WP_000149686.1\|2063946_2064507_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2064559_2065489_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001792184.1\|2065681_2065855_-	hypothetical protein	NA	NA	NA	NA
WP_001021210.1\|2065906_2067286_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181315.1\|2067405_2068434_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2068703_2069105_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2069677_2069851_-	hypothetical protein	NA	NA	NA	NA
WP_001188043.1\|2070301_2071342_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2071398_2072241_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2072237_2072795_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2072854_2073379_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2073499_2074063_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1\|2074128_2074869_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763043.1\|2074868_2075741_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	1.0e-27	36.0
WP_000645727.1\|2075737_2076418_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991306.1\|2076418_2077315_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	5.0e-17	30.2
WP_000691584.1\|2077311_2077692_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2077949_2078126_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2078368_2078467_-	hypothetical protein	NA	NA	NA	NA
WP_001068542.1\|2078666_2079953_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000671712.1\|2080231_2080522_-	MAP domain-containing protein	NA	NA	NA	NA
WP_001557458.1\|2080536_2081967_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669791.1\|2082923_2083103_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
WP_001791826.1\|2083413_2083674_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|2083725_2084076_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_001110820.1\|2084586_2084883_-	peptidoglycan hydrolase	A0A1P8L6B4	Staphylococcus_phage	1.6e-49	95.9
WP_000920038.1\|2085572_2086064_-	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
WP_000861035.1\|2086278_2087010_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	1.8e-145	99.2
WP_000611512.1\|2087021_2087276_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_031762631.1\|2087327_2087435_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|2087487_2087664_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000750412.1\|2087772_2088546_-	staphylococcal enterotoxin type A	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
WP_000340977.1\|2088918_2089293_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262621.1\|2089348_2089636_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
WP_001000058.1\|2089681_2089834_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_000582139.1\|2089826_2093609_-	hypothetical protein	A0A1X9H096	Staphylococcus_phage	0.0e+00	99.5
WP_000567408.1\|2093624_2095109_-\|tail	phage tail protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_001795393.1\|2095105_2099635_-\|tail	phage tail tape measure protein	A0A1X9H084	Staphylococcus_phage	0.0e+00	100.0
WP_001096355.1\|2099879_2100230_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_072050172.1\|2100279_2100504_-	hypothetical protein	A0A075LYE8	Staphylococcus_phage	8.8e-32	98.6
WP_000268741.1\|2100545_2101190_-\|tail	phage tail protein	W5R9H4	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1\|2101190_2101598_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114227.1\|2101594_2101999_-	hypothetical protein	G4KNQ5	Staphylococcus_phage	2.1e-68	99.3
WP_000755150.1\|2101995_2102358_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000150936.1\|2102341_2102626_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|2102615_2102900_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154559.1\|2102919_2104065_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
WP_000642728.1\|2104088_2104826_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025274.1\|2104809_2105997_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|2106012_2107674_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|2107670_2108015_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988330.1\|2108144_2108444_-	HNH endonuclease	G4KNP8	Staphylococcus_phage	4.6e-52	100.0
WP_000590122.1\|2108675_2109092_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000265043.1\|2109119_2109320_-	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
WP_010924771.1\|2109327_2109480_-	hypothetical protein	A0A2D1G5C4	Staphylococcus_phage	1.6e-13	100.0
WP_000195778.1\|2109467_2109674_-	DUF1381 domain-containing protein	S4V684	Staphylococcus_phage	2.8e-24	82.4
WP_001209219.1\|2109690_2109864_-	hypothetical protein	S4SVD5	Staphylococcus_phage	3.6e-25	100.0
WP_000181819.1\|2109900_2110434_-	dUTP pyrophosphatase	A0A0H3U2T1	Staphylococcus_phage	1.6e-95	100.0
WP_000700108.1\|2110426_2110669_-	hypothetical protein	A0A2I6PF40	Staphylococcus_phage	3.7e-36	100.0
WP_001065101.1\|2110658_2110895_-	DUF1024 family protein	A0A0H3U313	Staphylococcus_phage	5.3e-35	100.0
WP_001793991.1\|2110887_2111259_-	hypothetical protein	A0ZS31	Staphylococcus_virus	3.6e-62	96.7
WP_000131382.1\|2111267_2111510_-	hypothetical protein	A0A0H3U4B0	Staphylococcus_phage	1.6e-39	98.8
WP_000101288.1\|2111513_2111882_-	hypothetical protein	A0A0H3U2T3	Staphylococcus_phage	2.0e-49	100.0
WP_000401977.1\|2111894_2112299_-	RusA family crossover junction endodeoxyribonuclease	A0A0H3U2W2	Staphylococcus_phage	1.4e-72	100.0
WP_000338530.1\|2112307_2112526_-	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
WP_000148333.1\|2112532_2113426_-	DnaD domain-containing protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
WP_000934760.1\|2113455_2113926_-	single-stranded DNA-binding protein	A0EWX3	Staphylococcus_phage	7.4e-81	99.4
WP_071621397.1\|2113926_2114544_-	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	9.1e-87	100.0
WP_000138475.1\|2114624_2115545_-	recombinase	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_000700557.1\|2115546_2117490_-	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	98.0
WP_001205732.1\|2117498_2117762_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291483.1\|2117770_2118031_-	DUF1108 family protein	A0A2I6PEM2	Staphylococcus_phage	1.2e-40	93.0
WP_000165366.1\|2118035_2118338_-	DUF2482 family protein	A0A0F6N3N3	Staphylococcus_phage	8.0e-28	62.0
WP_000066023.1\|2118427_2118589_-	DUF1270 family protein	C8CGY5	Staphylococcus_phage	2.0e-17	88.7
WP_001120197.1\|2118585_2118906_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000275058.1\|2118960_2119593_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_000939496.1\|2119607_2119748_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_001148861.1\|2119778_2119976_-	hypothetical protein	A0A1W6JPV3	Staphylococcus_phage	1.2e-24	100.0
WP_110232075.1\|2119991_2120747_-	oxidoreductase	A0A1P8L6G2	Staphylococcus_phage	1.3e-138	99.6
WP_000351243.1\|2120803_2121343_+	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_000435341.1\|2121366_2121627_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000639927.1\|2121640_2121883_-	DUF739 family protein	Q9G038	Staphylococcus_virus	2.8e-39	100.0
WP_001083967.1\|2122046_2122763_+	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	9.2e-131	100.0
WP_000804507.1\|2122774_2123632_+	restriction endonuclease	R9QTP0	Staphylococcus_phage	3.5e-161	99.6
WP_000705248.1\|2123676_2123859_+	hypothetical protein	M9NSW6	Staphylococcus_phage	4.1e-27	100.0
WP_000825947.1\|2123958_2124423_+	hypothetical protein	A0EWV3	Staphylococcus_phage	1.1e-28	100.0
WP_000857191.1\|2124481_2125519_+\|integrase	site-specific integrase	A0EWV2	Staphylococcus_phage	9.1e-180	100.0
WP_000595392.1\|2126637_2127654_-	bi-component leukocidin LukGH subunit G	A0A1X9IGW5	Staphylococcus_phage	6.7e-26	30.2
WP_000791413.1\|2127675_2128731_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	7.4e-36	34.6
WP_000206624.1\|2129166_2130369_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_001045082.1\|2130676_2131984_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000746599.1\|2133000_2133723_+	exotoxin	A0A1X9H080	Staphylococcus_phage	2.1e-26	34.9
WP_000278088.1\|2133891_2134692_-	staphylococcal enterotoxin type C3	A0A097PAT7	Streptococcus_pyogenes_phage	6.1e-51	47.5
WP_001035616.1\|2135478_2136039_+	DUF4888 domain-containing protein	Q4ZBG8	Staphylococcus_virus	5.4e-62	68.1
WP_001035599.1\|2136917_2137622_+	toxic shock syndrome toxin TSST-1	NA	NA	NA	NA
WP_001293088.1\|2137776_2138346_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	7.9e-101	97.4
WP_000358774.1\|2138342_2138684_-	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.4e-57	99.1
WP_000771368.1\|2138686_2139214_-\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
WP_000448770.1\|2139264_2139483_-	hypothetical protein	NA	NA	NA	NA
WP_000846280.1\|2139500_2140079_-	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
WP_001047698.1\|2140879_2141521_-	hypothetical protein	Q4ZE67	Staphylococcus_phage	7.2e-111	93.0
WP_000356942.1\|2141517_2141898_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	1.7e-67	96.8
WP_000447473.1\|2142207_2143917_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	1.4e-302	92.8
WP_001002689.1\|2143930_2144800_-	hypothetical protein	Q4ZE74	Staphylococcus_phage	1.5e-164	96.2
WP_001078344.1\|2144864_2145191_-	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.5e-48	89.8
WP_001058495.1\|2145193_2145403_-	hypothetical protein	Q4ZE76	Staphylococcus_phage	2.9e-29	94.2
WP_000784885.1\|2145395_2145542_-	hypothetical protein	NA	NA	NA	NA
WP_000481967.1\|2145538_2145856_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000153640.1\|2145860_2146079_-	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000620857.1\|2146251_2146926_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_000179343.1\|2146939_2148112_+\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	5.8e-215	96.2
WP_000240642.1\|2148180_2149797_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
WP_000917289.1\|2149872_2150157_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
2153349:2153373	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP029674

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

14902 : 23259

Staphylococcus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001106006.1\|14902_15577_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	2.2e-126	97.3
WP_000889978.1\|15847_15943_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_001568510.1\|16107_16773_+\|transposase	IS6-like element IS257-2 family transposase	A0A0N9RU54	Staphylococcus_phage	5.9e-108	91.6
WP_001028144.1\|17345_18785_-	aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0
WP_000393259.1\|18785_19178_-	GNAT family N-acetyltransferase	A0A0N7GFH7	Staphylococcus_phage	6.9e-72	100.0
WP_001105984.1\|19669_20344_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	3.8e-126	98.2
WP_001807342.1\|20970_21537_-	multidrug-binding transcriptional regulator QacR	NA	NA	NA	NA
WP_000622776.1\|21714_23259_+	quaternary ammonium compound efflux MFS transporter QacA	A0A0M3UL24	Mycobacterium_phage	4.2e-32	26.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP029675

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP029674

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection