CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP030110	Enterococcus faecium strain BM4105-RF chromosome, complete genome	3 crisprs	cas9,cas1,cas2,csn2,DEDDh,cas3,csa3,DinG,cas14j	1	2	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP030110_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030110_1

334524-335086

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRT

8 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP030110_1

>merge|NZ_CP030110|1|334524-335086|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTTACCGATTGCCAACACTTCTAATCCAAAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACAACTTTTCCATCTCTACCACCCTCTGGGAAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACACAAGACTATGTTAGTGCTGCTTAGAGCTGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACCTTATATGACAGCTTATAAAGTGTTATGTAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACATGCCTCGAGTGCTGTCGTGTGTGTGCTGTGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACCTTTTCCTAATAATTTACAATCATCAATATGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTTAATAGTTAACGGAAATCACGATCGCGGGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTGATTTGTGTCCTCGATTTGCACTTTTAGTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

>NZ_CP030110|1|1|334524-335021|PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTACCGATTGCCAACACTTCTAATCCAAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AACTTTTCCATCTCTACCACCCTCTGGGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACAAGACTATGTTAGTGCTGCTTAGAGCTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTATATGACAGCTTATAAAGTGTTATGTA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGCCTCGAGTGCTGTCGTGTGTGTGCTGT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTTTCCTAATAATTTACAATCATCAATAT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTAATAGTTAACGGAAATCACGATCGCGG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC

>NZ_CP030110|1|1|334524-335086|CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTACCGATTGCCAACACTTCTAATCCAAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AACTTTTCCATCTCTACCACCCTCTGGGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACAAGACTATGTTAGTGCTGCTTAGAGCTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTATATGACAGCTTATAAAGTGTTATGTA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGCCTCGAGTGCTGTCGTGTGTGTGCTGT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTTTCCTAATAATTTACAATCATCAATAT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTAATAGTTAACGGAAATCACGATCGCGG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTGATTTGTGTCCTCGATTTGCACTTTTA
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

>NZ_CP030110|1|1|334524-335086|CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTACCGATTGCCAACACTTCTAATCCAAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AACTTTTCCATCTCTACCACCCTCTGGGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ACAAGACTATGTTAGTGCTGCTTAGAGCTG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTATATGACAGCTTATAAAGTGTTATGTA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATGCCTCGAGTGCTGTCGTGTGTGTGCTGT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTTTTCCTAATAATTTACAATCATCAATAT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTTAATAGTTAACGGAAATCACGATCGCGG
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTGATTTGTGTCCTCGATTTGCACTTTTA
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030110.1\|WP_002348322.1\|340835_342275_-\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|375760
NZ_CP030110.1\|WP_002348323.1\|338276_340829_+\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP030110.1\|WP_002310651.1\|335256_335622_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NZ_CP030110.1\|WP_025478103.1\|324754_325615_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_002292507.1\|335618_335984_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NZ_CP030110.1\|WP_002320713.1\|343945_344857_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|132175
NZ_CP030110.1\|WP_002292523.1\|346611_346911_+\|malonate-decarboxylase-subunit-delta	unknown	unknown	gnl\|CDD\|188283
NZ_CP030110.1\|WP_002335161.1\|328550_332573_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP030110.1\|WP_002348321.1\|342418_342781_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197
NZ_CP030110.1\|WP_002310643.1\|328344_328542_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_002310648.1\|333436_333781_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP030110.1\|WP_002310660.1\|344863_346510_+\|malonate-decarboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|379906
NZ_CP030110.1\|WP_002347855.1\|323647_324607_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP030110.1\|WP_002310652.1\|336144_337572_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|311953
NZ_CP030110.1\|WP_002292500.1\|322264_323398_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176243
NZ_CP030110.1\|WP_002287569.1\|327899_328028_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_025478098.1\|342968_343826_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP030110.1\|WP_002348338.1\|332573_333440_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP030110.1\|WP_002310641.1\|326148_327843_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NZ_CP030110.1\|WP_025478102.1\|333770_334433_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408

Protein	Function_ID	Function_description	E-value
NZ_CP030110.1\|WP_002348322.1\|340835_342275_-\|HTH-domain-containing-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	3.55805e-38
NZ_CP030110.1\|WP_002348323.1\|338276_340829_+\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP030110.1\|WP_002310651.1\|335256_335622_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	1.12042e-21
NZ_CP030110.1\|WP_002292507.1\|335618_335984_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	8.2154e-25
NZ_CP030110.1\|WP_002320713.1\|343945_344857_+\|ACP-S-malonyltransferase	gnl\|CDD\|132175	TIGR03131, malonate_mdcH, malonate decarboxylase, epsilon subunit. Members of this protein family are the epsilon subunit of malonate decarboxylase. This subunit has malonyl-CoA/dephospho-CoA acyltransferase activity. Malonate decarboxylase may be a soluble enzyme, or linked to membrane subunits and active as a sodium pump. The epsilon subunit is closely related to the malonyl CoA-acyl carrier protein (ACP) transacylase family described by TIGR00128, but acts on an ACP subunit of malonate decarboxylase that has an unusual coenzyme A derivative as its prothetic group.	8.48016e-67
NZ_CP030110.1\|WP_002335161.1\|328550_332573_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP030110.1\|WP_002348321.1\|342418_342781_+\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.06856e-20
NZ_CP030110.1\|WP_002348338.1\|332573_333440_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	6.57421e-121
NZ_CP030110.1\|WP_002310660.1\|344863_346510_+\|malonate-decarboxylase-subunit-alpha	gnl\|CDD\|379906	pfam16957, Mal_decarbox_Al, Malonate decarboxylase, alpha subunit, transporter. Mal_decarbox_Al is a family of Na+-transporting carboxylic acid decarboxylases.	0
NZ_CP030110.1\|WP_002347855.1\|323647_324607_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	6.348e-54
NZ_CP030110.1\|WP_002310652.1\|336144_337572_-\|hypothetical-protein	gnl\|CDD\|311953	pfam08280, HTH_Mga, M protein trans-acting positive regulator (MGA) HTH domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions.	0.00286938
NZ_CP030110.1\|WP_002292500.1\|322264_323398_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	1.57106e-174
NZ_CP030110.1\|WP_002310648.1\|333436_333781_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.51394e-45
NZ_CP030110.1\|WP_025478098.1\|342968_343826_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.12473e-38
NZ_CP030110.1\|WP_002292523.1\|346611_346911_+\|malonate-decarboxylase-subunit-delta	gnl\|CDD\|188283	TIGR03130, malonate_delta, malonate decarboxylase acyl carrier protein. Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.	5.72696e-47
NZ_CP030110.1\|WP_002310641.1\|326148_327843_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NZ_CP030110.1\|WP_025478102.1\|333770_334433_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.29943e-107

>NZ_CP030110.1|WP_025478102.1|333770_334433_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLEQPLSLEKATFLIVEDVTVFAKIVKWFYQYSESHELKLFNDKYKELKESDLLIITDVLGFDINSASTLKLIYADLERQLNEKVEVKSMIDKLTATISELIGYELLDHELDLEGDEITVLELFKALGIKIETRSDTIFEKLLELLQVYKYLSKKKLLVLINVCSYLTEEEISEVQNYISLYHMEVLFVEPRSIKGIKQFVLDKDYFLNLENMV
>NZ_CP030110.1|WP_002310648.1|333436_333781_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETADERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNPTASQAMLKRLKSNNPKKGFVTLLTVTEKQFARMVYLSGERDTSVANSDKRVIYLGEDEDAES
>NZ_CP030110.1|WP_002348338.1|332573_333440_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNTHSKLAYVNNHLIFKNAEKTERLHLSEIDVLLLETTDITITTMLLKRLVDEKILVLFCDDKRLPVAKLLPFYSRHDSSLQLTRQLAWSPEKKGQVWTAIISQKIQNQSNFLQKQSFTEKAESIQELHEGLLEFDPTNREGHAARIYFQTLFGTKFTREENNEINAGLDYGYTLLLSMFAREIVKNGCMTQFGLKHANQFNDFNLASDFMEPFRPVIDEIVYRYRNCEFPVIKRRLFDLFTNKYSYGKKEMFLTNIVSDYTSKVIKVLNNETEGVPQFRI
>NZ_CP030110.1|WP_002335161.1|328550_332573_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKEYTIGLDIGTNSVGWSVLTDDYRLVSKKMKVAGNTEKSSTKKNFWGVRLFDEGQTAEARRSKRTARRRLARRRQRILELQKIFAPEILKIDEHFFARLNESFLVLDEKKQSRHPVFATIKQEKSYHQTYPTIYHLRQALADSSEKADIRLVYLAMAHLLKYRGHFLIEGELNTENSSVTETFRQFLSTYNQQFSEADDKQTEKLDEAVDCSFVFTEKMSKTKKAETLLKYFPHEKSNGYLSQFIKLMVGNQGNFKNVFGLEEEAKLQFSKETYEEDLEELLEKIGDDYIDLFVQAKNVYDAVLLSEILSDSTKNTRAKLSAGMIRRYDAHKEDLVLLKRFVKENLPKKYRAFFGDNSVNGYAGYIEGHATQEDFYKFVKKELTGIRGSEVFLTKIEQENFLRKQRTFDNGVIPHQIHLTELRAIIANQKKHYPFLKEEQEKLESLLTFKIPYYVGPLAKKQENSPFAWLIRKSEEKIKPWNLPEIVDMEGSAVRFIERMINTDMYMPHNKVLPKNSLLYQKFSIYNELTKVRYQDERGQMNYFSSIEKKEIFHELFEKNRKVTKKDLQEFLYLKYDIKHAELSGIEKAFNASYTTYHDFLTMSENKREMKQWLEDPELASMFEEIIKTLTVFEDREMIKTRLSHHEATLGKHIIKKLTKKHYTGWGRLSKELIQGIRDKQSNKTILDYLINDDDFPHHRNRNFMQLINDDSLSFKKEIKKAQMITDTENLEEIVKELTGSPAIKKGILQSLKIVDEIVGIMGYEPANIVVEMARENQTTGRGLKSSRPRLKALEESLKDFGSQLLKEYPTDNSSLQKDRLYLYYLQNGRDMYTGAPLDIHRLSDYDIDHIIPRSFTTDNSIDNKVLVSSKENRLKKDDVPSEKVVKKMRSFWYDLYSSKLISKRKLDNLTKIKLTEEDKAGFIKRQLVETRQITKHVAGILHHRFNKAEDTNEPIRKVRIITLKSALVSQFRNRFGIYKVREINEYHHAHDAYLNGVVALALLKKYPQLAPEFVYGEYLKFNAHKANKATVKKEFYSNIMKFFESDTPVCDENGEIFWDKSKSIAQVKKVINHHHMNIVKKTEIQKGGFSKETVEPKKDSSKLLPRKNNWDPAKYGGLGSPNVAYTVAFTYEKGKARKRTNALEGITIMEREAFEQSPVLFLKNKGYEQAEIEMKLPKYALFELENGRKRMVASNKEAQKANSFLLPEHLVTLLYHAKQYDEISHKESFDYVNEHHKEFSEVFARVLEFAGKYTLAEKNIEKLEKIYKENQTDDLAKLASSFVNLMQFNAMGAPADFKFFDVTIPRKRYTSLTEIWQSTIIHQSITGLYETRIRMGK
>NZ_CP030110.1|WP_002310643.1|328344_328542_+|hypothetical-protein
MILKSKAQKKRREQRCFKKADDGQSLILTCYIDLNATNIFIIAKITAFTIGVFVFSIMMSCWMKG
>NZ_CP030110.1|WP_002287569.1|327899_328028_-|hypothetical-protein
MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI
>NZ_CP030110.1|WP_002310641.1|326148_327843_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAEEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDNITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQEEEHVTVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITSLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSKVDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE
>NZ_CP030110.1|WP_025478103.1|324754_325615_+|hypothetical-protein
MKQIQNKWNKRIIVMISSVCLFCLTVMLCLISTLANQHFMLEQNMQSDYAKKVAAEINQEIQSYHYEIGAPAEALEKIVSEELVQKNIELFIHNRYEKEPVELIGEKEVEEKLQEIINTYKQEEAEDDPFASEENNLLIYMTSGIFRRGIQSIYLMSFIDQILTIRERMVSFLPVISSILLVLLSGVFYLYRMSWKKVLWSFAVVIGGAGFQLLSLSVSLYLYDMTSQLDIRTQALQHLLDTYILSFIQFFSVVAIVEVVIAAGLWWIGKRVNTEKMVFSKRNEYK
>NZ_CP030110.1|WP_002347855.1|323647_324607_+|IS30-family-transposase
MTYTHLTTDELVIIESYFKINQSIAKTAHCLNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI
>NZ_CP030110.1|WP_002292500.1|322264_323398_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAVTWQGKQKMEIRNVDDPRILEPTDAIIRITATAICGSDLHLYHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMESQCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNNLPDEKVLFLSDILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKAANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGTISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYEMIAEGLFDPTQIITHSLPLEEAAQAYEIFDKKEDKNIKVVLKP
>NZ_CP030110.1|WP_002310651.1|335256_335622_+|DUF1622-domain-containing-protein
MFNTQLIGYLEWIIAILNICSIGILIAGIVLVLFKLFDWSHVKKNYAERNARNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVISYFLNQEIEDKEKQRRGEVG
>NZ_CP030110.1|WP_002292507.1|335618_335984_+|DUF1622-domain-containing-protein
MTTELMQFLLPYFEKLVLGLDIFAICLLIWGVCLSIKDFLKYLFVHTEAKNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIRTIISYFLNKEIGPVDVPNK
>NZ_CP030110.1|WP_002310652.1|336144_337572_-|hypothetical-protein
MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSYLLHVCKTTLLNDINNIKKEFEEQIVYTHREKDCYTLYFSEHIPRCKIMQQLTQNSLFLKTCLLYLEENEPDYLQLTECEFISVSKAYSLKKQVLAYFHDCGIEIDRYSPRFTEMERRLLLLNVAYRLGSFKSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQLCTVTIDPTFIEEIKKRPIYNYVESAWETTDFQTYYKKEEFAFILTLFNLCNYGCHSYQLIAEDFQQLHQVFIDNTPEIKELVATFETHFHQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTLFSSWAKRLPYDLRFNPNCMRAFVIELSGILRLTKERLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYASISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIERAIVSAVQNK
>NZ_CP030110.1|WP_002348323.1|338276_340829_+|HAD-IC-family-P-type-ATPase
MNWYKLTVEDTLKNHQTSTEGLSQEERQKRLTDQGYNEIEARQQTKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEESLNGLKQLMGQEAIVLSNGMQVKIPAKELVKGDVIVLRAGYVVPADVRLIEVHDLLVEESILTGESEASEKNHSVLAAEESIGDQKNMAFSGTLVQFGSAVGVVVETGNTTEIGKINQALQSVEQQTTPLIKKINRLNKQIFQGILCLILFLVVFTTFRYGMDWHILLSAMIALVVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNEMTVVDVAAKEETRVLSIMKNCQELKTKEEQKIENLSGNPTELALIRHTETANLPLKKIEAKIPFSSEYKYMATMHTEEKGTVIYVKGAPEVLLAKSTLSYSEQEAWGQTATAFAKKGQRVLGFAYKKVDSKQELTHESLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKMITGDHKDTAKAIVEQIGLKHTAKVLEGIDLDLMSEEELTRQVPKVDVFARTTPEHKLRIVKALQKNGEIVGMTGDGVNDAPALKRADIGIAMGIKGSEVSKQAADMVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALILNRPLPLSPVQILWVNMVTTITLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVALLIMVPAYLLAMQFEGQSLQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKSLFLSLGILALLQGMVIFLPIGQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREFSR
>NZ_CP030110.1|WP_002348322.1|340835_342275_-|HTH-domain-containing-protein
MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTERTIFSDLQSIRSHLPEGWDIFSDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLFTKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACIRGKERAIRTFYHRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKANCRLDSSIHINSTLSSLYDSALKKLYLKEGIYLKDTELSFASFCFLESWNYNNNYGQEIARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLVLKYHESPILIEPLERQYHRFLETYDQQYAHLYQQKENLLNDLKKEMEINEPNYFLQLLSLLIQQTIFSIKPNLFNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDSLDIPIVYISSIPTKNELNRLTELTFKTFL
>NZ_CP030110.1|WP_002348321.1|342418_342781_+|hypothetical-protein
MLTKKELIDHIDETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVLMSVPEEKIYDDASDHRIIDILDLKVDPELGGILRGKEGYFPAYHMNKEHWISVDLRKIEKLDELAGLIDESFKSTQ
>NZ_CP030110.1|WP_025478098.1|342968_343826_-|LysR-family-transcriptional-regulator
MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELGVPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIFKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK
>NZ_CP030110.1|WP_002320713.1|343945_344857_+|ACP-S-malonyltransferase
MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENYQDTVFIQLALLTKAVFYLDEMEKNGIQPDIVAGHSIGAFCAAVACRSLTFENAAELVYHRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSIEGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKNTDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKFGVDKGIRTINLDQHGIDDATFLYQKWR
>NZ_CP030110.1|WP_002310660.1|344863_346510_+|malonate-decarboxylase-subunit-alpha
MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLIAPGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKIDFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNLYTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDKLPRVDIPGDWVDVVVKADQPYQLEALFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLKGKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSNRTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPAWQSLRNNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSEDTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDRLRDAGIVKLPEDLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS
>NZ_CP030110.1|WP_002292523.1|346611_346911_+|malonate-decarboxylase-subunit-delta
MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKKESTVKICTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK

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Crispr_ID: NZ_CP030110_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030110_2

1123733-1123836

Orphan

II-A,II-B

Consensus_repeat	Method
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030110_2

>merge|NZ_CP030110|2|1123733-1123836|CRISPRCasFinder
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCCATGACACAGATATTGACCTATGAGCAACAGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC

>NZ_CP030110|2|2|1123733-1123836|CRISPRCasFinder
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC	ATGACACAGATATTGACCTATGAGCAAC
AGTTTTAGATCTATGTTAATTTGAATGATACCAAATCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030110.1\|WP_002308971.1\|1129704_1130094_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372239
NZ_CP030110.1\|WP_080475480.1\|1115982_1117572_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273925
NZ_CP030110.1\|WP_002345979.1\|1119800_1120244_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_002313654.1\|1117616_1118948_+\|6-phospho-alpha-glucosidase	unknown	unknown	gnl\|CDD\|133434
NZ_CP030110.1\|WP_065763921.1\|1130113_1132618_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|315512
NZ_CP030110.1\|WP_065763918.1\|1135700_1135928_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_065763922.1\|1125279_1128363_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|227268
NZ_CP030110.1\|WP_002345981.1\|1112846_1113215_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227933
NZ_CP030110.1\|WP_002347855.1\|1121719_1122679_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP030110.1\|WP_002308925.1\|1120452_1121043_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153234
NZ_CP030110.1\|WP_065763919.1\|1134651_1135686_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090
NZ_CP030110.1\|WP_002308919.1\|1115008_1115719_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_002334775.1\|1119032_1119800_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP030110.1\|WP_002308970.1\|1129470_1129695_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_065763917.1\|1135924_1136464_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_002334759.1\|1123878_1125156_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP030110.1\|WP_002308968.1\|1128483_1129467_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372237
NZ_CP030110.1\|WP_065763676.1\|1113364_1113859_+\|prolyl-tRNA-editing-protein	unknown	unknown	gnl\|CDD\|239827
NZ_CP030110.1\|WP_065763920.1\|1132632_1134594_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227596
NZ_CP030110.1\|WP_002308918.1\|1113882_1114893_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132883

Protein	Function_ID	Function_description	E-value
NZ_CP030110.1\|WP_002308971.1\|1129704_1130094_+\|hypothetical-protein	gnl\|CDD\|372239	pfam12648, TcpE, TcpE family. This family of proteins includes TcpE a conjugative transposon membrane protein.This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 168 amino acids in length.	8.62001e-15
NZ_CP030110.1\|WP_080475480.1\|1115982_1117572_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273925	TIGR02005, PTS-IIBC-alpha, PTS system, alpha-glucoside-specific IIBC component. This model represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella have been proposed to transport the five non-standard isomers of sucrose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP030110.1\|WP_002313654.1\|1117616_1118948_+\|6-phospho-alpha-glucosidase	gnl\|CDD\|133434	cd05298, GH4_GlvA_pagL_like, Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases. Bacillus subtilis GlvA and Clostridium acetobutylicum pagL are 6-phospho-alpha-glucosidase, catalyzing the hydrolysis of alpha-glucopyranoside bonds to release glucose from oligosaccharides. The substrate specificities of other members of this subgroup are unknown. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP_PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases, which include 6-phospho-beta-glucosidases, 6-phospho-alpha-glucosidases, alpha-glucosidases/alpha-glucuronidases (only from Thermotoga), and alpha-galactosidases. Members of this subfamily are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP030110.1\|WP_065763922.1\|1125279_1128363_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|227268	COG4932, COG4932, Predicted outer membrane protein [Cell envelope biogenesis, outer membrane].	1.4447e-30
NZ_CP030110.1\|WP_002308925.1\|1120452_1121043_-\|glutamine-amidotransferase	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	6.83953e-75
NZ_CP030110.1\|WP_002347855.1\|1121719_1122679_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	6.348e-54
NZ_CP030110.1\|WP_065763921.1\|1130113_1132618_+\|ATP-binding-protein	gnl\|CDD\|315512	pfam12846, AAA_10, AAA-like domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	4.96127e-142
NZ_CP030110.1\|WP_065763919.1\|1134651_1135686_+\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	1.10625e-29
NZ_CP030110.1\|WP_002345981.1\|1112846_1113215_-\|hypothetical-protein	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	1.63691e-24
NZ_CP030110.1\|WP_002334775.1\|1119032_1119800_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	4.51248e-40
NZ_CP030110.1\|WP_002334759.1\|1123878_1125156_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.00006e-08
NZ_CP030110.1\|WP_002308968.1\|1128483_1129467_+\|conjugal-transfer-protein	gnl\|CDD\|372237	pfam12642, TpcC, Conjugative transposon protein TcpC. This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.	1.91037e-44
NZ_CP030110.1\|WP_065763676.1\|1113364_1113859_+\|prolyl-tRNA-editing-protein	gnl\|CDD\|239827	cd04335, PrdX_deacylase, This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.	5.59169e-32
NZ_CP030110.1\|WP_065763920.1\|1132632_1134594_+\|hypothetical-protein	gnl\|CDD\|227596	COG5271, MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain [General function prediction only].	0.00636636
NZ_CP030110.1\|WP_002308918.1\|1113882_1114893_+\|LD-carboxypeptidase	gnl\|CDD\|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	5.16056e-116

>NZ_CP030110.1|WP_002347855.1|1121719_1122679_-|IS30-family-transposase
MTYTHLTTDELVIIESYFKINQSIAKTAHCLNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI
>NZ_CP030110.1|WP_002308925.1|1120452_1121043_-|glutamine-amidotransferase
MKTAVTFLLEEYADWEGAYITSTLNQNEGWQNKTASIQSEVTSMGGLKTKIDYLIEQIPEKIDLFIMIGGNSWDIENHHLYLIIDKFLKTGVPVAAICGAVDYLAQSGLLQGYKHTGNMQFPWLESENYQNKEDFIEQQAVKDHNLITANGTAPIESTDLILQAVHFETEEIRQKTIRLYKLGYYDYYEKYGDSFS
>NZ_CP030110.1|WP_002345979.1|1119800_1120244_+|hypothetical-protein
MRRDRIEGLWKHILLGYWIAAAFLFYFYAILMTIRMNGVIHEAFFHNPYVALGSLFPFLMLFQASILYFLEKRTIDISLLRIYLQFTVVQQVITGNLIGALLAFLYVRSLKRCGKKSTIYSKVLVLSSTIFIGTISLLAIFLLLRMS
>NZ_CP030110.1|WP_002334775.1|1119032_1119800_+|MurR/RpiR-family-transcriptional-regulator
MELEKLIHQHAEKLSELDRGILNFILSDPSLIQNLKITDLAERLYVSKSSIMRTTKKLGFSGYSEFKYFLRHVTNKENGLRTKEDIFEKQLEDIQQTLHYMKAVNLKPILQCLDRSKMIYCYATGFSQKKVIDEFYKMMLGIGKRVMVLPNKTEFDMAMPLITLEDMAIIVSLSGETHEVKENLTAFELQKIPVLTITAAGDNYFTRHSTYHLNYYCNCFILGKENKPFQSLISLSCLADYLVRAYGVYTLREES
>NZ_CP030110.1|WP_002313654.1|1117616_1118948_+|6-phospho-alpha-glucosidase
MKKFSITIAGGGSTFTPGIVLMLLKHLDRFPIRQIKFYDNLEERQTRIASACEILLKERAPDILFTATTDPETAFTDVDFVMAHIRVGLYAMREKDEKIPLKYGVVGQETCGPGGIAYGMRSIGGVLELIDYMEKYSPNAWMLNYSNPAAIVAEATRKLRPKAKIINICDMPVGIEERMAQAIGLASRKEMVVRYYGLNHFGWWTDIRDTEGNDLMPKIQEYVSQFGYALPSESQESQQTDASWKHTFMKAKEVYDIDPTTLPNTYLKYYFYPQDEVAHTNPEFTRANEVMVGREKQVFNECDRITSSGSAENTILEIDEHASYIVDLARAIAYNTHERMLLIVPNNGAIENFDESAMVEIPCIVGSNGPEPLIQGKIPRFQKGLMEQQVAVEKLVVEAWEERSYQKLWQALTLSKIVPNAKVAKNLLDDLVSVNQEYWPELK
>NZ_CP030110.1|WP_080475480.1|1115982_1117572_+|PTS-transporter-subunit-EIIC
MIMEKIQRFGGAMFTPVLLFSFSGIMVALCIIFKNPMLVGSIATEGTAWYSIWSVVESGAWTVFNQMELLFVIGLPIGLAKKASARAVMEAFVVYITCNYFISTMLGFYSGFFGVDFSADPGGASGLKMIAGIKTLDTGIIGAILISAVVVYLHNRFFDKKLPDFLGIYQGSSFVVIISFFIMLPIAFLICLIWPKIQSAISSLQGFLAGAGIFGVWLYTFLERILIPTGLHHFIYAPFAFGLAVVEEGIARYWMTHLQEFARSEQPLKHLFPEGGFALHGNSKIFASPGIAAAFYFTARPENRKKVLMILIPATLTAVLAGITEPLEFTFLFISPPLFAIHSLLAATMAAIMYGFGVVGDIGGGFIDLFVKVWIPLFQNHKGMIFTQLVIGLAFTGIYFIVFRYLIIKFDIATTGREENTDAVKLYTKKDYKEKERKTSKTEIENVYENQAAIYLEGFGGAGNIEKVTNCATRLRITVKNEMLVLEDTIFKEGGAHGVVRNGNAFQVIVGLDVPQVREQFERLLEIEQ
>NZ_CP030110.1|WP_002308919.1|1115008_1115719_-|hypothetical-protein
MKKLGFILASISLFLVGCTSASKETSESSATAVKSSIRQTSSAEKSSTQKSASSESNTSSTTSKLSESNPSSISSGTVDTSLSSTADTSFSQSSQSVDPLAGYSDLQIEYARVWLAVKGNTFKDASGDFELHVIHYPAGTPIDPYDAGSVGYPKDVVMLTGKYGYQGILVYSSNHDGTITSYPVPSHWQIPADQASDPAFIKKTTQEIIDHASVVAIPTGNPNDVKQLIDVTVIDN
>NZ_CP030110.1|WP_002308918.1|1113882_1114893_+|LD-carboxypeptidase
MIRYPLLGKNTTIGVIAPSSGVAEEHHLLLEMALKSMEEKSFHVVTGKTLWTQDKEKSAPARERADEFNQMMKDENIQMIFPPWGGELLIEILDSVDFDALQPKWIVGYSDISTLLLAITLKTGIATAHGTNLIDLRGNYSDKTTAMWKSVLETGKGESILQRSSEKYQKEWHHEQPSPSVFHLTEPTNWQTVSGEAVRIKGRLLGGCIDTIRHLIGTPYGDVQTFKRTYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFEDSSGIMFGRSAAEDLLDYRMKDVYEDLSKELNIPILYDIDCGHVPPQLTLINGAYAEVSVKDGKETILQTFI
>NZ_CP030110.1|WP_065763676.1|1113364_1113859_+|prolyl-tRNA-editing-protein
MIDLAKKFSHANIYFELYHHRAIYTNEDALVVKKEQGFTGTETKSLFLKDKKDNNYVYLTFTTKQTDFKALGKIIGKRLSIVSSEHMEEQTGQKQGAVSPFGYEEQIPIIIDEELLSKEKLVFAPGRPDQTMVIKTFDLNKIIQLLKIPMFLMPANENNNNQTK
>NZ_CP030110.1|WP_002345981.1|1112846_1113215_-|hypothetical-protein
MEKFRLIIDQIKEKENQQKINDLFSKIAKTYPQLDTTVKWNQPIFTDHGTFIIAFSFAENHFSIAPEKAAIRALEKTIQEIGYIYTDNVIKVPWKSAINWELIDHFISFNIEDKKDHNKFWR
>NZ_CP030110.1|WP_002334759.1|1123878_1125156_+|hypothetical-protein
MKKKVHWGVVGATIIVAGGMAVFTINEQNYSRQVEAVASELSTHKKQLQKIETEIAGLYADEHKQFLSSDVTQAKIDSLKKTIEKFKSEAESHAKKVETLRKQDQETCQKELVDITKLDEKINEVQMIFDQTQAVNSLFSTPYIENAEINEEAIIIDDLNSEMIEEKKEKIELENLEENEFSSAISKAIKSAENQLAQIERARKVVEELYKDGKPTDKVTRETLESVKKEVELIKNEKAKKSFNEPLKAIEEKVTADEKAEAERVAAEEAKRQEEQASENQATQQTEVPETQSATTDPVDTPTTPNRPVQNVTENITVQPTTPVAPPTNSGSGSNTGGTTSTPGSNTSGGSTGGGMTPAPTPTPTPEAPYALNPYRGSGTMYTSNSSAIAAGENWILTSPNSSGGYNIIDEYWSDGSVRYYLELY
>NZ_CP030110.1|WP_065763922.1|1125279_1128363_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKKYQIKLRIWLMLGILFGSFLSQPMTALAITNNQEQSEKTESVQNEQENEPDIVEQFLQKNNLIRGEDGKLYTTTPSTYVNESIHDILSGNQLTKAANQVVYVDPSTNVANIDIHLSNGSREYGWYGKRVNGQIALCIEQGVAVNVGSNGGYTAVLQDTELMKRISLIKYYGIILPGHTLQREIMTQILAYEQQGIYPTSISGVFSMADYQAFKSNVMANVNKFYTKPSFDGRTVTLKVGESITLNDTTGAFSNYESNAVVNTSNVLIEKNGNMVKITATKESNQSGMVRFRYNIPANYAGTPVIYNHPYTQNVLLGRVRDPSFVTFNINVLKNGNARIRKVDETTKQPLAGAVFRFTTSDGQSREITTGSDGYATWNDLLVDTRVTIQEIKAPNGYILNSTPQTITIRANETTTVTMDNKEQLANLTVIKEDEETGNTPQGAAQLIGAVYELTDGNGASVAKLTMEDVNGVAQAELKGLKLGTYYLQEIEPPKGYNLDPTKYTVQLTYAGQNETVAIHRKTVTDRVIKGHIEGYKLGSRPLIPQTITEILNQISNKNQDIKPPLEGVELTATSHTTGQEYVQVTGKNGYFRFENLPYDTYTIEETKGVDGYLLIEPFEVTITEEGYTHFFLLEDKIIESRLHIVKVDEETGENIPYAGAQFKIFDTWANDGEGAFVSMQRPNDTESTDIFETNEKGEIVTTESLAWGIDRYELHEIKAPEGYVPLEEPLVFSVTEEDAGALIRLEVPNRLARQNIQLIKRDRLNEQPLANVPFNLFKLETDEAGESTEVLLDEYLTDETGEINIEGLPYGEYKFVEGEPLEGYLPLEDALEFSVTVEKDGELIVLEAFNERKQLELMSLFTDVNGKKELDPTVDHRLKDTVWVKGAAIEVGHTYTVFTQYKNTKTGEVVSEATSTYTAKSKEDEFDVFLDLKANTVKDGDQLTATHVLYYEEEQLNEVAREDDLTNKDQTVSFKTPEQPKENKSETPKKQTTLPKTGSVHTILGVVLGGLLVTLVVFVWLSRAKK
>NZ_CP030110.1|WP_002308968.1|1128483_1129467_+|conjugal-transfer-protein
MKLKTIKKKEKKEKKPKVKKLSQKRANKIVFTGMSLLMIASAVGVIRANVVATNFDNLTDKVDQLAKSKNEKSIQKEVFDYSALSFYATSFAEEYLNYDASANEEEKKERLDRLEKYLSVDVDAVDETSKSQKEFIRRFKSAAVVQIKEESECLLVSLNVIYETEKEEEKKTLTQEMVLPIQTKNQLFSIVGRPYFLATTLPQGKTTELKQAEASLDVPPQEKEAIEKFLTLFFEKYANGEKQELMLLMKEPVQTSGVTEFISLNENEIKYFETKQKEVKGIQVSVTFADKQTGMTHTEDFSLWLTQTENSYFVRTLKHYFTEKEGN
>NZ_CP030110.1|WP_002308970.1|1129470_1129695_+|hypothetical-protein
MNVSNLDNFMRTGFITLLSFAVILLIFKHWRGAEWLKIGSVILIALILNDFATNQGRNIFNLVKWFLGLFGITM
>NZ_CP030110.1|WP_002308971.1|1129704_1130094_+|hypothetical-protein
MKHYDYSRGLKAPYSIQVISSPKGKALWVFAQPLNMSYLLMLFFLLFVTGVFWYKVRIPNIAGINLNLLLMLSVPHKVARWYSEAELDGKSTNLFLKDFIVYLKNFVMDQRPIIAFERVDQLEEFSFKR
>NZ_CP030110.1|WP_065763921.1|1130113_1132618_+|ATP-binding-protein
MQLEYPLSEYMHENMLLTQEKTAIAYYRIRSETVMLTDFEKKQKTKKKVARALKRLKGSGGFEINLLPVNADIRGKMGAMRSLIDPENHAVGVDKLMKTAQILENEMGMVYEYAWIIGVPLVKKEIAIDLKENISKAVNHVTETIVKGLGFDVALEKEWAKDYQEQEQEIYQNLSELLIERLTEDELYYYQAYQFLKNIPHERQDVLASQTFENLMETKIQPIFSGGLHFQCDYGESYVSYLPVGDIGVFLDGNHLLEIVQKMPFPVEVKIQASFAESKGQLALSGRSARARTRTKNIMQEAHLAGSKQKRKIVEGQLSLDDLDQKIDDGVDILDWKAVLVVSGSTKKQLQARKKYLINRFDGLGIPLLKATFDDPYLFQSTLFGNFLRMKDKKWQHTSTIESFAELNFFTSLKAGTNLGYYFGRVDTTLEEKEDRKSILLNSKNLIYMNLFLANKQDIVGKKTNNPHWALTGDTGNGKSVTAKKLFMECATLKDRVLYIDPKKEMRRQFMRTINDPAYQKKYPLDTAFVRSFNFVTLDVRDKKNLGVLDPIVLFDETEAIATAKAMLTNIYEGIWNLKQKTEINETIAAIVKERKSGKKVGFWQVVEKLASSSIPDVQDMGRFLISTIKGSILELAFSHGEVPGLSFEKKVTILEIEDLDLPTDKNEHMDENKRLSVTLMFALGTFCSKFGSRNPKQETVTFFDESWIFQSSPEGKAILKSMKRIGRSFNNFLVLITQSVNDLDDKEDGTGFGTVICFDEVQNREGILQYLNLPINEQNMKWVSNMVQGQCLLKDMFNQVNRVVVHVLFEEWLELFKTVDDSDASVMENHFAV
>NZ_CP030110.1|WP_065763920.1|1132632_1134594_+|hypothetical-protein
MKFLIDSYDAYMVGGGLLDKGWQVVNWFFVGLPFFFLKLCVSFFLFCESVLNQSDYFIAKQAEMFDMSVQILRNFGGTGFGRGTLMGLAIMLSAYYLLYHFFSNRHNFSQSLLHYVVVLLLFFGWFGQITTRQGTYNTSSFFIQSVNSIVKTVQNQFISGTNYGSDSDQSPMFDATVKQTFYFVNSGSLDGTMENGEKLDEAKLLQVPNLSKEEKETFKKDREQYIDSLENENPYFAQDGSKTMEKSFAIWVGVANLFILALPVLYINMMLTIIQILVNLLILAFPILALASFFPRCQMLMFKFFKTLIGILFMPVIYGVFISVLFWVNQLIDQVFLHAAQGINENLLNVLSGSILLLGTRLIMVLVKIVFISTVWKNRYRILGFFADGQIQQPIFEKKVNEKTKEGAEQISGASIGAAQLAAGAYTGNPNIALNGLSKILPDKAMTLGKEHFLDEENQFTGVKQGLGSLFRPSDYDDTELSIPEEDKMEMDQVDQQVEDEVLVDEEVDDKALEDVLAEINEADPTFDQSLSESDALISDDVLMSDLSDSDLTNDTEALFEQDEVAMSENEIPIDPTVLSEKMNVTVDNFDELQLSQEEQAYFDHAYDPELIANYSSEVEPIHQIEENFKSLESEETFFDAWEEEQKEPMEDW
>NZ_CP030110.1|WP_065763919.1|1134651_1135686_+|CHAP-domain-containing-protein
MKKIAYIILGTCFAFLLPFLLFIGIFSANQNGSTSEFEPGTPQEQVALEVAQYVQQKGGTKEFAAAWIGNMEHESGLIPSRIQSDLAFNPVWAYNPDIGGYAMGLAQWDSSRRVNMLNLAREQNEDWKAVAFQMDFAWYHDGSDSDLLKNMSNGTEIEKLAVDILKYWERAGTKDDPVEQNKRKTSAVNWYKRLFEGSLGGGSANIGGDKIDILESVMGQTINGGQCYGLTAYYVQKLGGPQMMGSGFMYAQSIGSDYDWQKYGWAVIFDPKPSEIKAGDVINWYAGEALSPGIYGHTGIIASVESEGKFITYEQNAEQGQICAKYARQWGREFNRVASVVRKK
>NZ_CP030110.1|WP_065763918.1|1135700_1135928_+|hypothetical-protein
MFFTHPGLTRRQVKEICAKFQCSQNEFVARRFEDGFLVSLRNKEYRVKFSPGRFSQIVFVKEVVRVTANRKQGRG
>NZ_CP030110.1|WP_065763917.1|1135924_1136464_+|hypothetical-protein
MKRILFLIGTTLSVLTLVACSSPDEQAETTESVKDSSIMEAVENSSLKLENAKAESSQPTATQEIVEEDREENPIEDHMELLQAYGEAYANFKTINHRNEKLKDLMTEECIQMNGIDVETGNALGSEGKVTSIYQNNQDEYAVLLDCIQNGSPIRILLLAKVEDNKIAEMTYNTLKREY

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Crispr_ID: NZ_CP030110_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030110_3

1695214-1695307

Orphan

Consensus_repeat	Method
TGAGGAAGAAGGTGTTGTTTCTGCTGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030110_3

>merge|NZ_CP030110|3|1695214-1695307|CRISPRCasFinder
TGAGGAAGAAGGTGTTGTTTCTGCTGCATTGCTGCTTGAATCCCCTGCTTGATAAGTTGTGTCACTTGAGGAAGAAGGTGTTGTCTCTGCTGCA

>NZ_CP030110|3|3|1695214-1695307|CRISPRCasFinder
TGAGGAAGAAGGTGTTGTTTCTGCTGCA	TTGCTGCTTGAATCCCCTGCTTGATAAGTTGTGTCACT
TGAGGAAGAAGGTGTTGTCTCTGCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030110.1\|WP_002313886.1\|1703903_1704620_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP030110.1\|WP_002309583.1\|1685071_1686280_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|237339
NZ_CP030110.1\|WP_002309597.1\|1695758_1697162_-\|ATP-dependent-DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|223588
NZ_CP030110.1\|WP_002290180.1\|1688414_1689674_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP030110.1\|WP_002345050.1\|1692964_1694194_-\|30S-ribosomal-protein-S1	unknown	unknown	gnl\|CDD\|235851
NZ_CP030110.1\|WP_033627214.1\|1705179_1705941_-\|segregation/condensation-protein-A	unknown	unknown	gnl\|CDD\|234635
NZ_CP030110.1\|WP_002309595.1\|1694328_1695009_-\|(d)CMP-kinase	unknown	unknown	gnl\|CDD\|234579
NZ_CP030110.1\|WP_002309587.1\|1687827_1688409_-\|IDEAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|235145
NZ_CP030110.1\|WP_002309607.1\|1704620_1705196_-\|SMC-Scp-complex-subunit-ScpB	unknown	unknown	gnl\|CDD\|234657
NZ_CP030110.1\|WP_002290168.1\|1701061_1702585_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP030110.1\|WP_002345049.1\|1698593_1699331_-\|carboxymethylenebutenolidase	unknown	unknown	gnl\|CDD\|315383
NZ_CP030110.1\|WP_002290178.1\|1690954_1691230_-\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259853
NZ_CP030110.1\|WP_002309599.1\|1698210_1698432_+\|ferredoxin	unknown	unknown	gnl\|CDD\|224064
NZ_CP030110.1\|WP_002309590.1\|1689675_1690722_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030110.1\|WP_002309605.1\|1702962_1703574_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|226129
NZ_CP030110.1\|WP_002309586.1\|1686870_1687746_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP030110.1\|WP_002309598.1\|1697148_1698180_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227291
NZ_CP030110.1\|WP_002309592.1\|1691472_1692783_-\|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl\|CDD\|234628
NZ_CP030110.1\|WP_002309584.1\|1686390_1686723_-\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212138
NZ_CP030110.1\|WP_002309602.1\|1699484_1700825_-\|Sapep-family-Mn(2+)-dependent-dipeptidase	unknown	unknown	gnl\|CDD\|235965

Protein	Function_ID	Function_description	E-value
NZ_CP030110.1\|WP_002313886.1\|1703903_1704620_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	4.27886e-102
NZ_CP030110.1\|WP_002309583.1\|1685071_1686280_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|237339	PRK13299, PRK13299, tRNA CCA-pyrophosphorylase; Provisional.	0
NZ_CP030110.1\|WP_002309597.1\|1695758_1697162_-\|ATP-dependent-DNA-helicase-RecQ	gnl\|CDD\|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	2.1197e-157
NZ_CP030110.1\|WP_002290180.1\|1688414_1689674_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	2.50473e-14
NZ_CP030110.1\|WP_002345050.1\|1692964_1694194_-\|30S-ribosomal-protein-S1	gnl\|CDD\|235851	PRK06676, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP030110.1\|WP_033627214.1\|1705179_1705941_-\|segregation/condensation-protein-A	gnl\|CDD\|234635	PRK00104, scpA, segregation and condensation protein A; Reviewed.	9.18517e-91
NZ_CP030110.1\|WP_002309595.1\|1694328_1695009_-\|(d)CMP-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	3.71691e-117
NZ_CP030110.1\|WP_002309587.1\|1687827_1688409_-\|IDEAL-domain-containing-protein	gnl\|CDD\|235145	PRK03636, PRK03636, hypothetical protein; Provisional.	1.62848e-61
NZ_CP030110.1\|WP_002309607.1\|1704620_1705196_-\|SMC-Scp-complex-subunit-ScpB	gnl\|CDD\|234657	PRK00135, scpB, segregation and condensation protein B; Reviewed.	8.8191e-67
NZ_CP030110.1\|WP_002290168.1\|1701061_1702585_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	6.5543e-165
NZ_CP030110.1\|WP_002345049.1\|1698593_1699331_-\|carboxymethylenebutenolidase	gnl\|CDD\|315383	pfam12695, Abhydrolase_5, Alpha/beta hydrolase family. This family contains a diverse range of alpha/beta hydrolase enzymes.	5.44071e-73
NZ_CP030110.1\|WP_002290178.1\|1690954_1691230_-\|HU-family-DNA-binding-protein	gnl\|CDD\|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	9.29619e-47
NZ_CP030110.1\|WP_002309599.1\|1698210_1698432_+\|ferredoxin	gnl\|CDD\|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	1.01037e-12
NZ_CP030110.1\|WP_002309605.1\|1702962_1703574_-\|ECF-transporter-S-component	gnl\|CDD\|226129	COG3601, COG3601, Predicted membrane protein [Function unknown].	7.22947e-38
NZ_CP030110.1\|WP_002309586.1\|1686870_1687746_+\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	5.34929e-87
NZ_CP030110.1\|WP_002309598.1\|1697148_1698180_-\|hypothetical-protein	gnl\|CDD\|227291	COG4955, COG4955, Uncharacterized protein conserved in bacteria [Function unknown].	4.74889e-24
NZ_CP030110.1\|WP_002309592.1\|1691472_1692783_-\|ribosome-biogenesis-GTPase-Der	gnl\|CDD\|234628	PRK00093, PRK00093, GTP-binding protein Der; Reviewed.	0
NZ_CP030110.1\|WP_002309584.1\|1686390_1686723_-\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212138	cd11531, NTP-PPase_BsYpjD, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs. This family includes a putative pyrophosphatase Ypjd from Bacillus subtilis (BsYpjD) and its homologs. Although its biological role has not been described in detail, BsYpjD shows significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, BsYpjD contains a single MazG-like domain.	2.55139e-43
NZ_CP030110.1\|WP_002309602.1\|1699484_1700825_-\|Sapep-family-Mn(2+)-dependent-dipeptidase	gnl\|CDD\|235965	PRK07205, PRK07205, hypothetical protein; Provisional.	0

>NZ_CP030110.1|WP_002309595.1|1694328_1695009_-|(d)CMP-kinase
MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYLAITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFTASKDVTLEIRQPDVTKAVSEVSAHGKVREELVAIQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKENQEKGIPTDLETLTKEIQARDHYDSTREVSPLQQAEDAVRIDTTGKSIPEVVAAIKAVVLEKGYLLF
>NZ_CP030110.1|WP_002345050.1|1692964_1694194_-|30S-ribosomal-protein-S1
MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIIGIEGAGVEGVVPAKELSTLPVEDINEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRLDAKKVWEDIERDFQDGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYKGKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFGAFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDEVNVKVLSINPEQERVSLSIKDTQPGPWSEIDTKAPVGAVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLHEGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILGNALKEEVEEKATDDSEK
>NZ_CP030110.1|WP_002309592.1|1691472_1692783_-|ribosome-biogenesis-GTPase-Der
MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYAKGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEMVAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAVKYFTEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFVSESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDKRVAGYAHEAGRGVIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQRLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKPPTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK
>NZ_CP030110.1|WP_002290178.1|1690954_1691230_-|HU-family-DNA-binding-protein
MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQLIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK
>NZ_CP030110.1|WP_002309590.1|1689675_1690722_-|hypothetical-protein
MELDYQVEEALTKVFYGETLVSQLRALSIDQPILFLTNQRYYDLFADKINPLFANQANNDWYICANTQCNHLTELKNLLDFTKRYPENQSMFVIGFGNEGIMDLAGFFQKHTILDSSLWLIPVSIRSLSRALTPQRTILQLPNRVVLQTINMPERIVYDQTISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFYQLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFFVWLDLLGYPIQWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQRPNEKELLRTMTVFQQIVSEIRGN
>NZ_CP030110.1|WP_002290180.1|1688414_1689674_-|tetratricopeptide-repeat-protein
MNTNSEKMLQALSDEDLAQAQLFLEKALKEDPADILAELGEELLAIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKESDYYPQSLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVIYETLLASGINEMSGISMQERLGQSLSMQGEFEAAIAPLEEALKEEKTDDRLFQLAFTNLQLKENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMVEEAQTVLEEGIKENPYQVELYHLASENAFRLHDKQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQMEETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRAQELLTHYLKLEPGDMEALSLLDDLTER
>NZ_CP030110.1|WP_002309587.1|1687827_1688409_-|IDEAL-domain-containing-protein
MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVHFVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECLFENAWQTREYLSILEDNPFSSWDASVSEEDTELIERYFQEKEEAAKLNMLYAQIDQALEDGDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN
>NZ_CP030110.1|WP_002309586.1|1686870_1687746_+|YitT-family-protein
MATRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLILRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEINLQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGISMGRSLLAFDIIVLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTGLQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQGFTYLKPQTRLLKKL
>NZ_CP030110.1|WP_002309584.1|1686390_1686723_-|nucleotide-pyrophosphohydrolase
MDEKRSLYSMQQEVDEYIQQFKVGYFSPLAQLARLTEEVGELAREVNHAYGEKSKKASEPDNSVAEELGDVLFVTMIMANSLNIDLTDVFEKNMEKFNQRDHNRFERKDK
>NZ_CP030110.1|WP_002309583.1|1685071_1686280_-|CCA-tRNA-nucleotidyltransferase
MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIHDVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDHVEFVRSLEEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDALRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERSAGIHAFIETECYICCPGLREEGEALLRFAELPSVPLKEESQAWTLLISQLDLKENEIRSFLKSWKCSNQMIKDVQALVQGLRQRKTGVLEPFELYFLGKKHALQVEELMTYFDETPQMDVVEESYDRLPIKSLSELAVDGKILLEESGKKPGKWVSEALQSAEKAVVEQRIENDKKQVLDFLSKEKLI
>NZ_CP030110.1|WP_002309597.1|1695758_1697162_-|ATP-dependent-DNA-helicase-RecQ
MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSLCYQLTGYLMDGMVLIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSRAERGYVLRHLSQYKFLFLSPEMLTNPSLLEQLKKQDIALYVVDEAHCVSQWGVDFRPEYQQLGKIREHLGNPVTLALTATATDLVAKDIRQVLFDRQPKEVRQSVNRQNISLFVRKTQQKEQELEQFMERAQGAAIIYCATKKEVERLYHLFRERFSVGYYHGGLDTAQRRQLQQQFVKNQLQFLIATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILLYQSGDERIHYFFNQLSREQRQSFELYLEYAAEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEKEFRLQQMLRYIHEEDCRRKFILAYFGEELSEKPQNCCDIDGAKVELLPKKKAFSKTEPLHWESILLNLFKKNMEH
>NZ_CP030110.1|WP_002309598.1|1697148_1698180_-|hypothetical-protein
MIVFILSLFSSRNKLRVSSLYQLLVGKRTTSVLIFGFTHELLFAHNSFPELKQDKFSQIMQKLAQQGWIEINENEAKLTSAGADRLSELHTEYTGLRFDRYGRTGETSWRLIKFAVQVISNLASGNQNYLPAETSPFYTFQLKKWLSGSRLSRGILIDSAYESLAQLFSEIPEGAADFLANQFSGNDRTGLLPYQLAKTNDESAVYLQQSRCIHLLLAQIEERPDSLWYVLIDPLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKKGTVTDHLIEWALFFDDFPYERILSQETVERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLRKEAIQNVNK
>NZ_CP030110.1|WP_002309599.1|1698210_1698432_+|ferredoxin
MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQQFVMPEEEAYVRKAYQKCPVRAILLENKI
>NZ_CP030110.1|WP_002345049.1|1698593_1699331_-|carboxymethylenebutenolidase
MKIFRRILIGLVIILGLLGGGGYYYIQQNTYEPSLEAQKVVKEGRNKEDYLFFEGEKKNQAKSPLLIFYPGALVDPESYSIWAQDLAKNGYSVAIVKMPLDLAVIGGNKADKIKEDFPDSDYVIGGHSLGGVMASRYANKNHSDSHLKGVFFMASYPDKKGTLKESAVPVLSITATKDKVLNQKAYEEAKQYLPERTEYVSINGGNHGGFGSYGEQKGDGEAEISNADQQTVIVNTLENWLKKLK
>NZ_CP030110.1|WP_002309602.1|1699484_1700825_-|Sapep-family-Mn(2+)-dependent-dipeptidase
MKQFVTEQHHEQALESLSELIRIPSVLDEADSGKGHPFGKKVIEALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPFDPTVKDGWLVGRGSQDDKGPSIAAMYAVKALMDAGVEFKTRIRFIFGTDEENLWRCLEKYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNDFSVKAGGALNVVPDAAPYSGEKISEVKEALKKHGFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDFGPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFKKEDLVAKLTKTAEKYELSYEEFDFLDSLYVPLDSELVKNLLGTYREITGDMTEPFVSGGATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK
>NZ_CP030110.1|WP_002290168.1|1701061_1702585_-|YfcC-family-protein
MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGNIVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGIINKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMMAVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLAISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFITFGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFLVMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWGEQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITAYQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF
>NZ_CP030110.1|WP_002309605.1|1702962_1703574_-|ECF-transporter-S-component
MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIPVLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSVKKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLIGIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQLEQRHTAVK
>NZ_CP030110.1|WP_002313886.1|1703903_1704620_-|rRNA-pseudouridine-synthase
MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGKHDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLDYDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLAKGIKIEGRKTSPAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLRPGDYRELNKKEVSSLLNHSK
>NZ_CP030110.1|WP_002309607.1|1704620_1705196_-|SMC-Scp-complex-subunit-ScpB
MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVANLVKELRDSYAQNPHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQPITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLEELPDTQEMEISLEEDVSPDLFFDGMNKGEQL
>NZ_CP030110.1|WP_033627214.1|1705179_1705941_-|segregation/condensation-protein-A
MTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPIQEFVTDDEELWEEDPREELVTQLLEYRKYKYAAEKLTEKAEERSLYYTKDPMNIDGLADVEKPLKRGQVKKIDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMIFIEERIKRNTHGCTFNSFFESPSKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP030110_1	1.1\|334560\|30\|NZ_CP030110\|PILER-CR,CRISPRCasFinder,CRT	334560-334589	30	NZ_CP030110.1	931161-931190	0	1.0

1. spacer 1.1|334560|30|NZ_CP030110|PILER-CR,CRISPRCasFinder,CRT matches to position: 931161-931190, mismatch: 0, identity: 1.0

tttaccgattgccaacacttctaatccaaa	CRISPR spacer
tttaccgattgccaacacttctaatccaaa	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP030110_1	1.6\|334890\|30\|NZ_CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	NC_011245	Borrelia duttonii Ly plasmid pl28, complete sequence	23714-23743	5	0.833
NZ_CP030110_1	1.6\|334890\|30\|NZ_CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	MN693212	Marine virus AFVG_25M426, complete genome	7433-7462	6	0.8
NZ_CP030110_1	1.4\|334758\|30\|NZ_CP030110\|PILER-CR,CRISPRCasFinder,CRT	334758-334787	30	MG592515	Vibrio phage 1.144.O._10N.286.45.B3, partial genome	27153-27182	7	0.767
NZ_CP030110_1	1.6\|334890\|30\|NZ_CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	NC_014023	Bacillus megaterium QM B1551 plasmid pBM700, complete sequence	73613-73642	8	0.733
NZ_CP030110_1	1.6\|334890\|30\|NZ_CP030110\|PILER-CR,CRISPRCasFinder,CRT	334890-334919	30	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	20379-20408	8	0.733

1. spacer 1.6|334890|30|NZ_CP030110|PILER-CR,CRISPRCasFinder,CRT matches to NC_011245 (Borrelia duttonii Ly plasmid pl28, complete sequence) position: , mismatch: 5, identity: 0.833

cttttcctaataatttacaatc-atcaatat	CRISPR spacer
attttactaataatttacaatctggcaata-	Protospacer
 **** **************** . *****

2. spacer 1.6|334890|30|NZ_CP030110|PILER-CR,CRISPRCasFinder,CRT matches to MN693212 (Marine virus AFVG_25M426, complete genome) position: , mismatch: 6, identity: 0.8

cttttcctaataatttacaatcatcaatat	CRISPR spacer
cttttgctaataatttacaatgttgtaaat	Protospacer
***** ***************  *  * **

3. spacer 1.4|334758|30|NZ_CP030110|PILER-CR,CRISPRCasFinder,CRT matches to MG592515 (Vibrio phage 1.144.O._10N.286.45.B3, partial genome) position: , mismatch: 7, identity: 0.767

cttatatgacagcttataaagtgttatgta	CRISPR spacer
ctctgatgacagattataaactgttatgct	Protospacer
**.  ******* ******* *******.

4. spacer 1.6|334890|30|NZ_CP030110|PILER-CR,CRISPRCasFinder,CRT matches to NC_014023 (Bacillus megaterium QM B1551 plasmid pBM700, complete sequence) position: , mismatch: 8, identity: 0.733

cttttcctaataatttacaatcatcaatat	CRISPR spacer
attttcctaataattgagaatcatttccct	Protospacer
 ************** * ******.  . *

5. spacer 1.6|334890|30|NZ_CP030110|PILER-CR,CRISPRCasFinder,CRT matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 8, identity: 0.733

cttttcctaataatttacaatcatcaatat	CRISPR spacer
attttcctaataattgagaatcattttcct	Protospacer
 ************** * ******.  . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

981292 : 1065014

Enterococcus_phage(20.93%)

capsid,portal,plate,tRNA,protease,holin,integrase,terminase,tail,head

attL 988719:988740|attR 1032855:1032876

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002308731.1\|981292_982054_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_002290284.1\|982189_982537_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_002348534.1\|982797_983091_+	DUF2087 domain-containing protein	NA	NA	NA	NA
WP_002348535.1\|983380_985045_+	acetolactate synthase AlsS	NA	NA	NA	NA
WP_002308805.1\|985057_985768_+	acetolactate decarboxylase	NA	NA	NA	NA
WP_002293167.1\|985896_986394_+	GAF domain-containing protein	NA	NA	NA	NA
WP_002289617.1\|986578_986839_+	hypothetical protein	NA	NA	NA	NA
WP_002348537.1\|987251_987788_-	glycopeptide antibiotics resistance protein	NA	NA	NA	NA
988719:988740	attL	NA	NA	NA	NA
WP_065763638.1\|988745_989888_-\|integrase	site-specific integrase	M1PRU8	Streptococcus_phage	6.3e-57	36.9
WP_065763639.1\|989994_990951_-	Abi family protein	X2L062	Streptococcus_phage	1.6e-82	48.6
WP_002306332.1\|991141_991348_-	hypothetical protein	NA	NA	NA	NA
WP_103557062.1\|991371_991473_-	LysM domain-containing protein	NA	NA	NA	NA
WP_065763640.1\|991744_992746_-	Abi family protein	A0A2H4JB40	uncultured_Caudovirales_phage	4.1e-28	26.7
WP_065763641.1\|992857_993277_-	hypothetical protein	NA	NA	NA	NA
WP_065763642.1\|993409_994063_-	hypothetical protein	NA	NA	NA	NA
WP_025479728.1\|994112_994541_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_065763643.1\|994545_994920_-	helix-turn-helix transcriptional regulator	A0A2P0ZLA1	Lactobacillus_phage	1.4e-21	45.5
WP_065763644.1\|995204_995390_+	helix-turn-helix transcriptional regulator	Q5YAA3	Bacillus_phage	3.8e-12	58.3
WP_065763645.1\|995403_995652_+	hypothetical protein	NA	NA	NA	NA
WP_065763646.1\|995859_996642_-	hypothetical protein	NA	NA	NA	NA
WP_065763647.1\|996694_997402_+	antirepressor	D2IYT0	Enterococcus_phage	2.0e-69	56.5
WP_065763648.1\|997577_997919_+	hypothetical protein	NA	NA	NA	NA
WP_065763649.1\|997911_998643_+	DUF1071 domain-containing protein	A0A2I7RDU5	Vibrio_phage	1.2e-45	53.6
WP_002333654.1\|998648_999335_+	hypothetical protein	C9E2N1	Enterococcus_phage	4.9e-89	70.0
WP_065763650.1\|999338_1000085_+	helix-turn-helix domain-containing protein	F8J194	Lactobacillus_virus	3.3e-30	58.8
WP_002293146.1\|1000096_1000366_+	hypothetical protein	NA	NA	NA	NA
WP_010721325.1\|1000527_1000830_+	hypothetical protein	NA	NA	NA	NA
WP_065763651.1\|1000826_1000988_+	antitoxin	NA	NA	NA	NA
WP_080475476.1\|1000984_1001296_+	hypothetical protein	NA	NA	NA	NA
WP_080475477.1\|1001398_1001929_+	hypothetical protein	A0A0S2MYJ7	Enterococcus_phage	3.7e-52	59.3
WP_080475478.1\|1002098_1002716_+	DUF1642 domain-containing protein	A0A141E1K4	Streptococcus_phage	5.1e-13	34.9
WP_065763654.1\|1002712_1003009_+	hypothetical protein	NA	NA	NA	NA
WP_010729117.1\|1003084_1003501_+	ArpU family phage transcriptional regulator	C9E2P5	Enterococcus_phage	1.4e-46	67.4
WP_065763655.1\|1003776_1004415_+	hypothetical protein	NA	NA	NA	NA
WP_002342126.1\|1004899_1005085_+	hypothetical protein	F0PII8	Enterococcus_phage	5.8e-21	82.0
WP_002342127.1\|1005077_1005341_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.6e-32	74.7
WP_065763656.1\|1005381_1005609_+	hypothetical protein	NA	NA	NA	NA
WP_065763657.1\|1005605_1005893_+	hypothetical protein	NA	NA	NA	NA
WP_002337263.1\|1006422_1006737_+	HNH endonuclease	A0A0K2CYS9	Paenibacillus_phage	5.2e-14	43.8
WP_002318055.1\|1007024_1007615_-	hypothetical protein	NA	NA	NA	NA
WP_010861569.1\|1007666_1008122_+\|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	3.1e-15	32.9
WP_065763658.1\|1008112_1009903_+\|terminase	terminase large subunit	A0A1B1P7R3	Bacillus_phage	5.9e-195	55.8
WP_016631239.1\|1009902_1011138_+\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	5.6e-120	53.8
WP_002318059.1\|1011172_1011898_+\|protease	Clp protease ClpP	A0A0B5A796	Paenibacillus_phage	3.7e-71	57.8
WP_065763659.1\|1011898_1013035_+\|capsid	phage major capsid protein	A0A0C5AEH1	Paenibacillus_phage	4.8e-134	65.9
WP_065763660.1\|1013108_1013471_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_080475479.1\|1013448_1013811_+\|head,tail	phage head-tail adapter protein	A0A059T6F2	Listeria_phage	9.0e-26	53.3
WP_065763661.1\|1013803_1014208_+	hypothetical protein	A0A2H4J7V9	uncultured_Caudovirales_phage	9.1e-19	37.9
WP_002371758.1\|1014204_1014615_+	hypothetical protein	A0A059T681	Listeria_phage	3.1e-22	47.2
WP_047927163.1\|1014675_1015263_+\|tail	phage tail protein	A0A2P0ZLF5	Lactobacillus_phage	2.7e-35	41.0
WP_065763662.1\|1015335_1015803_+	Ig domain-containing protein	A5GYM0	Lactococcus_phage	1.6e-06	52.6
WP_002337251.1\|1015848_1016157_+	hypothetical protein	NA	NA	NA	NA
WP_065763663.1\|1016351_1022987_+\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	5.0e-130	42.2
WP_065763664.1\|1022990_1023812_+\|tail	phage tail family protein	Q9T1A6	Listeria_phage	2.2e-56	44.6
WP_065763665.1\|1023820_1024864_+	hypothetical protein	Q9T1A5	Listeria_phage	5.7e-105	54.4
WP_065763666.1\|1024863_1025913_+	hypothetical protein	Q9T1A4	Listeria_phage	1.0e-21	31.9
WP_065763667.1\|1025912_1028186_+\|plate	BppU family phage baseplate upper protein	A0A0M4RT83	Enterococcus_phage	2.5e-65	42.1
WP_065763668.1\|1028204_1028651_+	hypothetical protein	NA	NA	NA	NA
WP_002298029.1\|1028652_1028790_+	XkdX family protein	NA	NA	NA	NA
WP_002306392.1\|1028827_1029121_+	hypothetical protein	NA	NA	NA	NA
WP_002334690.1\|1029143_1029341_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	8.6e-23	82.8
WP_065763669.1\|1029351_1030371_+	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	4.1e-60	66.1
WP_065763670.1\|1030560_1031586_-	hypothetical protein	NA	NA	NA	NA
WP_065763671.1\|1032450_1032753_-	hypothetical protein	NA	NA	NA	NA
WP_002290402.1\|1033508_1034282_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
1032855:1032876	attR	NA	NA	NA	NA
WP_002308810.1\|1034425_1034776_+	SdpI family protein	NA	NA	NA	NA
WP_002290404.1\|1034756_1035473_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.1e-34	36.2
WP_002313582.1\|1035472_1036921_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	6.0e-20	29.8
WP_002308814.1\|1036993_1037503_-	hypothetical protein	NA	NA	NA	NA
WP_002316381.1\|1037492_1038218_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_002308821.1\|1038389_1040510_-	LTA synthase family protein	W6LM83	Streptococcus_phage	7.5e-221	58.4
WP_002308823.1\|1040738_1041917_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	6.0e-103	49.2
WP_002313585.1\|1041932_1042685_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.3e-26	35.9
WP_002290411.1\|1042707_1043193_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_002336491.1\|1043263_1044517_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.7e-23	55.3
WP_002308828.1\|1044633_1045983_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_002290415.1\|1046094_1047441_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_002308846.1\|1047741_1048128_-	YxeA family protein	NA	NA	NA	NA
WP_002308849.1\|1048993_1049206_+	hypothetical protein	NA	NA	NA	NA
WP_002313630.1\|1049483_1051283_-	glycerophosphoryl diester phosphodiesterase	I6XE30	Staphylococcus_phage	6.3e-11	27.3
WP_002329369.1\|1051409_1052006_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	4.3e-33	41.1
WP_002308852.1\|1052376_1052721_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_002308853.1\|1052721_1053141_+	cupin domain-containing protein	NA	NA	NA	NA
WP_002308854.1\|1053230_1053584_-	hypothetical protein	NA	NA	NA	NA
WP_065763672.1\|1053549_1054881_-	DUF1576 domain-containing protein	NA	NA	NA	NA
WP_002308856.1\|1055136_1055703_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_065763673.1\|1056224_1058120_+	asparagine synthase (glutamine-hydrolyzing)	F2Y2L7	Organic_Lake_phycodnavirus	3.5e-20	26.2
WP_002308858.1\|1058201_1058648_-	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_002296119.1\|1058875_1059025_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_002308859.1\|1059112_1059631_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	5.4e-24	39.1
WP_002345988.1\|1059704_1060661_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_065763674.1\|1060826_1061633_+	ABC transporter ATP-binding protein	A0A1V0SJ29	Klosneuvirus	7.9e-14	30.0
WP_002313633.1\|1061629_1062619_+	iron ABC transporter permease	NA	NA	NA	NA
WP_002345986.1\|1062615_1063620_+	iron ABC transporter permease	NA	NA	NA	NA
WP_002313635.1\|1063753_1064296_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_002308868.1\|1064315_1065014_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_2

1596797 : 1605836

Synechococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002309479.1\|1596797_1597376_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-26	36.9
WP_033627216.1\|1597372_1598416_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.9e-61	43.9
WP_002313844.1\|1598447_1599887_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-53	33.3
WP_002313845.1\|1599871_1602094_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.6e-152	41.6
WP_002313846.1\|1602094_1602766_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002309490.1\|1602767_1603022_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002309491.1\|1603021_1603750_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.1e-41	40.9
WP_002309492.1\|1604005_1604383_+	hypothetical protein	NA	NA	NA	NA
WP_002306865.1\|1604540_1605836_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	33.1

DBSCAN-SWA_3

2009894 : 2018366

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002292349.1\|2009894_2012084_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	6.8e-286	66.7
WP_002292348.1\|2012398_2013001_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	4.9e-53	58.0
WP_002346307.1\|2013054_2014176_-	DNA polymerase IV	NA	NA	NA	NA
WP_002310240.1\|2014284_2015157_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	9.6e-90	60.4
WP_002288076.1\|2015225_2015573_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	5.1e-18	41.1
WP_002335412.1\|2015565_2016390_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_065763740.1\|2016425_2017364_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.3e-33	33.4
WP_002292340.1\|2017377_2017707_-	hypothetical protein	NA	NA	NA	NA
WP_002292339.1\|2017721_2018366_-	dTMP kinase	M1PSC7	Streptococcus_phage	4.2e-58	52.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP030110

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection