CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021773	Streptococcus agalactiae strain B105 chromosome, complete genome	2 crisprs	DEDDh,RT,csm6,csn2,cas2,cas1,cas9,DinG,cas3,csa3	0	9	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021773_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021773_1

1083273-1083836

TypeII

II-A

Consensus_repeat	Method
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CRT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	PILER-CR
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	PILER-CR

8 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP021773_1

>merge|NZ_CP021773|1|1083273-1083836|CRT,PILER-CR,CRISPRCasFinder,PILER-CR
CGGTGCCCTAGCATAATAACCGCACAGCTCTAAAACACATATCAGGAATATAAAAATCGTTCAAATGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTGCCTTTTAATTCAGCTCCCACTTTTTATCGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACCGATTTGCTCGTACATTATAAATACCACCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTTGTATATGACCCGTTACCGCTATCAAATAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACCTGGAATGTTAAATTTACCTTTTAGCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACATGTTGCCACTAGTTGCTCTTTATGAACAGGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACAGTTTCTTTTAAGTTCAATGTTTGTCAAATGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTTTACATTAAAAAAATGGACGAGCGGTCAAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>NZ_CP021773|1|1|1083273-1083836|CRT
CGGTGCCCTAGCATAATAACCGCACAGCTCTAAAAC	ACATATCAGGAATATAAAAATCGTTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACCTGGAATGTTAAATTTACCTTTTAGCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>NZ_CP021773|1|1|1083339-1083572|PILER-CR
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACCTGGAATGTTAAATTTACCTTTTAGCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA


>NZ_CP021773|1|1|1083339-1083836|CRISPRCasFinder
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACCTGGAATGTTAAATTTACCTTTTAGCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>NZ_CP021773|1|2|1083603-1083836|PILER-CR
	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACCTGGAATGTTAAATTTACCTTTTAGCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021773.1\|WP_000168912.1\|1072842_1075635_-\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_CP021773.1\|WP_000665411.1\|1075783_1076221_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP021773.1\|WP_001056394.1\|1069661_1070273_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP021773.1\|WP_001040110.1\|1085797_1089910_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP021773.1\|WP_000523795.1\|1091606_1092344_-\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_CP021773.1\|WP_001019130.1\|1080331_1082164_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP021773.1\|WP_000122196.1\|1084588_1084930_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP021773.1\|WP_000146567.1\|1070983_1071622_+\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP021773.1\|WP_000159234.1\|1093975_1094347_-\|YbgA-family-protein	unknown	unknown	gnl\|CDD\|377982
NZ_CP021773.1\|WP_000590710.1\|1083936_1084602_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP021773.1\|WP_000065314.1\|1071739_1072843_-\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_CP021773.1\|WP_000323544.1\|1090835_1091606_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP021773.1\|WP_000914665.1\|1092347_1093478_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP021773.1\|WP_000678305.1\|1077452_1080086_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|275380
NZ_CP021773.1\|WP_000438312.1\|1082299_1082716_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP021773.1\|WP_000929494.1\|1084926_1085796_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP021773.1\|WP_071659920.1\|1076220_1076685_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP021773.1\|WP_000180008.1\|1076693_1077353_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_CP021773.1\|WP_001241816.1\|1093570_1093951_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_CP021773.1\|WP_000653357.1\|1090189_1090846_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884

Protein	Function_ID	Function_description	E-value
NZ_CP021773.1\|WP_000168912.1\|1072842_1075635_-\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP021773.1\|WP_000665411.1\|1075783_1076221_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	9.78399e-86
NZ_CP021773.1\|WP_001056394.1\|1069661_1070273_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	6.1265e-31
NZ_CP021773.1\|WP_001040110.1\|1085797_1089910_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP021773.1\|WP_000523795.1\|1091606_1092344_-\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
NZ_CP021773.1\|WP_001019130.1\|1080331_1082164_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP021773.1\|WP_000122196.1\|1084588_1084930_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.83127e-50
NZ_CP021773.1\|WP_000146567.1\|1070983_1071622_+\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	1.14428e-70
NZ_CP021773.1\|WP_000159234.1\|1093975_1094347_-\|YbgA-family-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	6.08694e-28
NZ_CP021773.1\|WP_000590710.1\|1083936_1084602_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.57126e-122
NZ_CP021773.1\|WP_000065314.1\|1071739_1072843_-\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.12954e-104
NZ_CP021773.1\|WP_000323544.1\|1090835_1091606_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_CP021773.1\|WP_000914665.1\|1092347_1093478_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP021773.1\|WP_000678305.1\|1077452_1080086_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	2.83221e-22
NZ_CP021773.1\|WP_000438312.1\|1082299_1082716_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	1.21474e-79
NZ_CP021773.1\|WP_000929494.1\|1084926_1085796_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.45885e-137
NZ_CP021773.1\|WP_071659920.1\|1076220_1076685_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.76832e-16
NZ_CP021773.1\|WP_000180008.1\|1076693_1077353_-\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	1.30028e-33
NZ_CP021773.1\|WP_001241816.1\|1093570_1093951_-\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_CP021773.1\|WP_000653357.1\|1090189_1090846_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.75792e-52

>NZ_CP021773.1|WP_000438312.1|1082299_1082716_-|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESAAREIAIWFNN
>NZ_CP021773.1|WP_001019130.1|1080331_1082164_-|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIDPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_CP021773.1|WP_000678305.1|1077452_1080086_-|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSYHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHYPTSDGFLFNGRGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKADSKKQSPSSKKPRNENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDENQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLSSLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSRNKLKSLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_CP021773.1|WP_000180008.1|1076693_1077353_-|HD-domain-containing-protein
MTMVKREDVILNATENMVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKG
>NZ_CP021773.1|WP_071659920.1|1076220_1076685_-|GNAT-family-N-acetyltransferase
MIRRAKEKDLPAIAELLKQILVLHHGVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQCAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_CP021773.1|WP_000665411.1|1075783_1076221_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFDE
>NZ_CP021773.1|WP_000168912.1|1072842_1075635_-|cation-transporting-P-type-ATPase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKVLSEQLVPGDIVLIEEGDCISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENYQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINIQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDDAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKTLSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>NZ_CP021773.1|WP_000065314.1|1071739_1072843_-|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYQAEISLEFEKQFAAMVFTIPNIDYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGAGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRETK
>NZ_CP021773.1|WP_000146567.1|1070983_1071622_+|CatB-related-O-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIEAGSVITKDIPDYAVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKREFFNTLKSISENKNHKL
>NZ_CP021773.1|WP_001056394.1|1069661_1070273_-|TVP38/TMEM64-family-protein
MNMKLSKRYRFWQKVIKALGVLALIATLVLVVYLYKLGILNDSNELKDLVHKYEFWGPMIFIVAQIVQIVFPVIPGGVTTVAGFLIFGPTLGFIYNYIGIIIGSVILFWLVKFYGRKFVLLFMDQKTFDKYESKLETSGYEKFFIFCMASPISPADIMVMITGLSNMSIKRFVTIIMITKPISIIGYSYLWIYGGDILKNFLN
>NZ_CP021773.1|WP_000590710.1|1083936_1084602_-|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMMVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_CP021773.1|WP_000122196.1|1084588_1084930_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANFDSRLVFLGDSYDQD
>NZ_CP021773.1|WP_000929494.1|1084926_1085796_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLVFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARYDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLESFDTSNREGHAARIYFNTLFGNDFSREHDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYDGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_CP021773.1|WP_001040110.1|1085797_1089910_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGYSVVTDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTASDRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEDDKRGSKYPIFATMQEEKDYHEKFPTIYHLRKELADKKEKANLRLVYLALAHIIKFRGHFLIEDDSFDVRNTDIQRQYQAFLEIFDTTFENNHLLSQNIDVEGILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSVAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFTDSSKDGYAGYIEGKTNQGAFYKYLSKLLTKQEGSEYFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELKAIIRRQSEYYPFLKENLDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEELVDKEASAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRYKNEQGETYFFDSNIKQEIFDGVFKEHRKVSKKKLLDFLAKEYEEFRIVDVIGLDKENKAFNASLGTYHDLKKILDKDFLDNPDNESILEDIVQTLTLFEDREMIKKRLENYKDLFTESQLKKLYRRHYTGWGRLSAKLINGIRDKESQKTILDYLISDGRANRNFMQLIHDDGLSFKPIIDKAQAGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQVVVEMARENQTTNQGRRNTRQRYKLLEEGVKNLASDLNGNILKEYPTDNQALQNERLFLYYLQNGRDMYTGEALDIDNLSQYDIDHIVPQAFIKDDSIDNRVLVSSAKNRGKSDNVPSIDIVKARKAFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNDYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQVNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERFRFEKNPSAFLESKGYLNIRDDKLMILPKYSLFELENGRRRLLASAGELQKGNELALPTQYMKFLYLASRYNELKGKPEEIEQKQEFVVQHVSYFDDILQIINDFSNRVILADANLEKINKLYQDNKENISVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>NZ_CP021773.1|WP_000653357.1|1090189_1090846_-|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_CP021773.1|WP_000323544.1|1090835_1091606_-|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_CP021773.1|WP_000523795.1|1091606_1092344_-|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_CP021773.1|WP_000914665.1|1092347_1093478_-|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELSRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEVQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWDNVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKKGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_CP021773.1|WP_001241816.1|1093570_1093951_-|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_CP021773.1|WP_000159234.1|1093975_1094347_-|YbgA-family-protein
MTKEAELLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE

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Crispr_ID: NZ_CP021773_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021773_2

2212925-2213122

Orphan

Consensus_repeat	Method
CAGAGGCTAANCCAGAAG	CRT

4 spacers

The CRISPR arrays of NZ_CP021773_2

>merge|NZ_CP021773|2|2212925-2213122|CRT
CAGAAGTTAAACCAGACGTTAAGCCAGAGGCCAAACCAGAGGCTAAGCCAGAAGTTAAACCAGACGTTAAGCCAGAGGCCAAACCAGAGGCTAAGCCAGAAGTTAAATCAGACGTTAAGCCAGAGGCTAAGCCAGAAGCCAAACCAGAGGCTAAACCAGAAGTTAAACCAGACGTTAAGCCAGAGGCTAAACCAGAAG

>NZ_CP021773|2|2|2212925-2213122|CRT
CAGAAGTTAAACCAGACG	TTAAGCCAGAGGCCAAAC
CAGAGGCTAAGCCAGAAG	TTAAACCAGACGTTAAGCCAGAGGCCAAAC
CAGAGGCTAAGCCAGAAG	TTAAATCAGACGTTAAGC
CAGAGGCTAAGCCAGAAG	CCAAACCAGAGGCTAAACCAGAAGTTAAACCAGACGTTAAGC
CAGAGGCTAAACCAGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021773.1\|WP_000453153.1\|2203777_2204449_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NZ_CP021773.1\|WP_000145176.1\|2220737_2223239_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_CP021773.1\|WP_071659992.1\|2205896_2207540_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226987
NZ_CP021773.1\|WP_001182060.1\|2201745_2202525_+\|uridine-phosphorylase	unknown	unknown	gnl\|CDD\|350167
NZ_CP021773.1\|WP_000903266.1\|2223328_2223937_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021773.1\|WP_071659995.1\|2219355_2220522_-\|IS30-like-element-ISSag9-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP021773.1\|WP_000222146.1\|2215377_2216574_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133037
NZ_CP021773.1\|WP_000497678.1\|2211045_2211219_+\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|223762
NZ_CP021773.1\|WP_000074729.1\|2217666_2218914_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP021773.1\|WP_000887149.1\|2213521_2214061_+\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_CP021773.1\|WP_000010475.1\|2207559_2208444_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP021773.1\|WP_071659991.1\|2208487_2210809_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_CP021773.1\|WP_001159691.1\|2202545_2203748_+\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP021773.1\|WP_000730410.1\|2224029_2225418_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP021773.1\|WP_001093377.1\|2226332_2231048_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173801
NZ_CP021773.1\|WP_000953623.1\|2216778_2217624_+\|patatin-family-protein	unknown	unknown	gnl\|CDD\|132847
NZ_CP021773.1\|WP_000409543.1\|2214107_2215313_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133037
NZ_CP021773.1\|WP_001125579.1\|2200850_2201588_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP021773.1\|WP_000057521.1\|2210857_2211010_+\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
NZ_CP021773.1\|WP_000077169.1\|2204515_2205727_+\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430

Protein	Function_ID	Function_description	E-value
NZ_CP021773.1\|WP_000453153.1\|2203777_2204449_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	5.32157e-109
NZ_CP021773.1\|WP_000145176.1\|2220737_2223239_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP021773.1\|WP_071659992.1\|2205896_2207540_+\|hypothetical-protein	gnl\|CDD\|226987	COG4640, COG4640, Predicted membrane protein [Function unknown].	2.89333e-08
NZ_CP021773.1\|WP_001182060.1\|2201745_2202525_+\|uridine-phosphorylase	gnl\|CDD\|350167	cd17767, UP_EcUdp-like, uridine phosphorylases similar to Escherichia coli Udp and related phosphorylases. Uridine phosphorylase (UP) is specific for pyrimidines, and is involved in pyrimidine salvage and in the maintenance of uridine homeostasis. In addition to E. coli Udp, this subfamily includes Shewanella oneidensis MR-1 UP and Plasmodium falciparum purine nucleoside phosphorylase (PfPNP). PfPNP is an outlier in terms of genetic distance from the other families of PNPs. PfPNP is catalytically active for inosine and guanosine, and in addition, has a weak UP activity. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	4.65794e-137
NZ_CP021773.1\|WP_071659995.1\|2219355_2220522_-\|IS30-like-element-ISSag9-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.60425e-35
NZ_CP021773.1\|WP_000222146.1\|2215377_2216574_-\|hypothetical-protein	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	4.07197e-67
NZ_CP021773.1\|WP_000497678.1\|2211045_2211219_+\|preprotein-translocase-subunit-SecE	gnl\|CDD\|223762	COG0690, SecE, Preprotein translocase subunit SecE [Intracellular trafficking and secretion].	5.81702e-09
NZ_CP021773.1\|WP_000074729.1\|2217666_2218914_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.36923e-69
NZ_CP021773.1\|WP_000887149.1\|2213521_2214061_+\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	3.00072e-83
NZ_CP021773.1\|WP_000010475.1\|2207559_2208444_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.78283e-84
NZ_CP021773.1\|WP_071659991.1\|2208487_2210809_+\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	0
NZ_CP021773.1\|WP_001159691.1\|2202545_2203748_+\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	2.06818e-155
NZ_CP021773.1\|WP_000730410.1\|2224029_2225418_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.15512e-45
NZ_CP021773.1\|WP_001093377.1\|2226332_2231048_-\|S8-family-serine-peptidase	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.37759e-89
NZ_CP021773.1\|WP_000953623.1\|2216778_2217624_+\|patatin-family-protein	gnl\|CDD\|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	2.37781e-121
NZ_CP021773.1\|WP_000409543.1\|2214107_2215313_-\|hypothetical-protein	gnl\|CDD\|133037	cd04194, GT8_A4GalT_like, A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.	3.51587e-72
NZ_CP021773.1\|WP_001125579.1\|2200850_2201588_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.9213e-33
NZ_CP021773.1\|WP_000057521.1\|2210857_2211010_+\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	2.53308e-18
NZ_CP021773.1\|WP_000077169.1\|2204515_2205727_+\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0

>NZ_CP021773.1|WP_000497678.1|2211045_2211219_+|preprotein-translocase-subunit-SecE
MFVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVMDLINRF
>NZ_CP021773.1|WP_000057521.1|2210857_2211010_+|50S-ribosomal-protein-L33
MAQKKASLACTECGSRNYSIGVSSTPKPTRLEVNKFCKYCKKYTIHKETR
>NZ_CP021773.1|WP_071659991.1|2208487_2210809_+|penicillin-binding-protein
MKLFDKFIDLFRVDEDNDEMTRKNEQETREETSNLDGEEVYDIDDITRPSKSQYQRGIRHQKENAKSRLEWLQKVDRYLPSPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQSALKTTTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVNAGQLTKSQAKEAASIGMKNRLADTYAGKINDYKYPSYFDAVVNEAIDTYGISEKDIVNNGYKIYTALDQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGRVQSTKDAQFRSFNYATQSKRSPASTIKPLVVYSPAIASGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNMSSANKELGVALGGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINANVYGYTMAGKTGTTETDFNPNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTDSSAGTASNIFSTQASYILPYTKGSSFTHIENAYFQNGIGSVYNAQDASNTTNQESRSIINDLKDSASKAAQDISRAVEDSNFQEKVKDAWNSLKDYFR
>NZ_CP021773.1|WP_000010475.1|2207559_2208444_-|RluA-family-pseudouridine-synthase
MSFSLKIRNPYGEHTVKELLEDYFLIPRKIRHFLRVKKHVLINNEFINWQTVVQENDTITLIFDDEDYPTKKIPLGRAELIDCLYEDEHLIIVNKPEGMKTHGNQPNEIALLNHVSAYSGQTCYVVHRLDMETSGAVLFAKNPFILPLINQRLERKEIWREYWALVEGKFSPKHQVLRDKIGRNRHDRRKRIIDSKNGQHAMTIIDVLKYIQNSSLIKCRLETGRTHQIRIHLSHHGHPLIGDPLYNPSSNNERLMLHAHRLTLSHPLTCETISVEAPSSTFEKVLNNYKKGVG
>NZ_CP021773.1|WP_071659992.1|2205896_2207540_+|hypothetical-protein
MFDFFKKKVVKVCLVIFGIVLVSLLSLGFFYFSKGQVLSRFVAARSRTSGQAFDNIKEYMVWSDTGESITNDEANYANFEPLSKSEARKLGQEIKEGNKNDSMYLKRVGSRLGIFPDYRIANKPMSLTLKTNVPKLDVLLNQKKVATSNSDHFSVTVERLPRTHYTASLEGTSDGKEIKLKKDYDGKNQTIDLSVAFKSFTVTSNLMDGNLYFGDNRIAKLKDGSYSVENYPVTDGSKAYIKKVFNDGEITSHKQKLISIADNQTIKLDVDGLLNEKEAGQKLITAFNQLILYVSTGQDPQTLGTVFEKGAENDFYKGLKESIKAKFVTDNRKASHFTIPNIVLNKMTQVGKESYQVNFAADYDFNYDKSTDPDKKTYGHIIQNLTGNFIMKKSGNSYLISNDGKKDITVAKETNKVKADPVSIFPENLVGSWKGEVEDGTVTMTFDKDGKVTQKKVYKDSKSKESNHSAKVTKLEDKGNGLYLYQYESGTDTTTFVTGGIGGLKVKYAYGIKIEGNKIIPVIWQTSSDGEFDYHKPLLSKPLTKQL
>NZ_CP021773.1|WP_000077169.1|2204515_2205727_+|phosphopentomutase
MSQFDRIHLVVLDSVGIGAAPDANDFVNAGVPDGASDTLGHISKTVGLAVPNMAKIGLGNIPRPQALKTVPAEENPSGYATKLQEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEDIITKIEDFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPLEELYRICEYARSITMERPALLGRIIARPYVGDPGNFTRTANRHDYAVSPFEDTVLNKLDQAGIDTYAVGKINDIFNGSGINHDMGHNKSNSHGIDTLIKTMGLSEFEKGFSFTNLVDFDALYGHRRDPHGYRDCLHEFDERLPEIISAMRDKDLLLITADHGNDPTYAGTDHTREYIPLLAYSPSFTGNGLIPVGHFADISATVADNFGVDTAMIGESFLQDLV
>NZ_CP021773.1|WP_000453153.1|2203777_2204449_+|deoxyribose-phosphate-aldolase
MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIKNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVDEGVKIKAAGGISSLEDAEKFIALGASRLGTSRIIKIVKNQKVEEGTY
>NZ_CP021773.1|WP_001159691.1|2202545_2203748_+|NupC/NupG-family-nucleoside-CNT-transporter
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQVVSVVSTGVTKVINCGQAGLNFVFGSLADSGTKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYLGRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILFPQTEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSGIAVLCPEKRGTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
>NZ_CP021773.1|WP_001182060.1|2201745_2202525_+|uridine-phosphorylase
MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNAVLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGIDLDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQCKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFLVVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ
>NZ_CP021773.1|WP_001125579.1|2200850_2201588_-|GntR-family-transcriptional-regulator
MPKNELNNKLNKLKHVQVYNKIFNMIQDGTYSPGMQLPSEPELAGQLNVSRATLRKSLALLQEDHLVKNIRGKGNFIRENSSNLSENGYENRQHPIKTCLTSKITEVELEFRVEVPAEAITASLKQETPVVVIADRWYHTDDGPLAYTLSFIPIELISDAEISLHDTKQLLNFIEEGIYHEGISSHSQSHLGYATSGNFSATKYTLSDHGQFILIQETIFNQEKILMCNKHYVPIEHFELSITSH
>NZ_CP021773.1|WP_000887149.1|2213521_2214061_+|transcription-termination/antitermination-protein-NusG
MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVNVEKNGKTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRSILISMGQTVDVFDTNIKEGDVVQIIDGAFIGQEGRVVEIENNKVKLMINMFGSETQAELELYQVAEL
>NZ_CP021773.1|WP_000409543.1|2214107_2215313_-|hypothetical-protein
MEKAVALAVDSNYLDKALVTIKSICVYNRNITFYLFNQDTPVEWVRNINRKLEPLGSKLINVKIYNYDIAHLTTFLTVSTWFRLFLADYIPSSRVLYLDSDIIVNTNLDYLFELDFKGHYLAAVKDPHKNEEGGFNAGMLLANLELWREDGLTKTLLKTAEELHRVVKTGDQSILNIVCHNRWLSLNKTWNFQTYDVVSRYNHRSYLYLNIENRTPNIIHFLTSDKPWNENSVARFRELWWYYFQLDFCQLTGKQRKVISYEKSMELLSVSDIHLFTLTSSDNLEHIESLICRCPTVQFHIGAYTTVSNKLSKLEQYPNVLVYPELIEARIEKLITLATAYLDINHGPEVGNILQRVHLKQKPIYSFNNTSHQENITKHIVNHNSIDNMVVLINELNLNQL
>NZ_CP021773.1|WP_000222146.1|2215377_2216574_-|hypothetical-protein
MTYQKTVVLAGDYSYIRQIETTLKSLCVYHENLSIFIFNQDIPQEWFLAMKDRVGQTGNQIQDVKLFHDHLSPKWENKKLNHINYMTYARYFIPQYISADTVLYLDSDLVVTTNLDNLFQISLDNAYLAAVPALFGLGYGFNAGVMVINNQRWRQENMTIKLIEKNQKEIENANEGDQTILNRMFENQVIYLDDTYNFQIGFDMGAAIDGHKFIFDIPITPLPKIIHYISGIKPWQTLSNMRLREVWWHYNLLEWSSIISSKKVFGLDHPIKTQNYRLNFLIVTTSDCIPSISELVTALPDCLFHIAAPTVMSDILISLLAFENIRLHKTYTPPIIDKLLAEADIYLDINVFGKMEGILQKMSQSEKPILTTRECNSQLVPETVFASIDDLINYLQSI
>NZ_CP021773.1|WP_000953623.1|2216778_2217624_+|patatin-family-protein
MLSVGLVLEGGGMRGLYTAGVLDAFLDAGIKIDGIVSVSAGALFGVNFVSRQRERALRYNKKYLSHPEYMSLRSWLRTGNFVNKDFTYYEVPMKLDVFDDEAFKKSSIDFYVVATEMTSGKPEYFKIDSVFEQMEILRASSALPVVSKMVDWQGKKYLDGGLSDSIPVDFARGLGFDKLIVVMTRPLNYQKKPSSGRLYKTLYRKYPNFVKTASNRYQQYNNSLEKVMSLEKTGDLFAIRPSKSLVIGRLEKNPDKLDSIYQLGMKYAKSVMPELNSYLMK
>NZ_CP021773.1|WP_000074729.1|2217666_2218914_-|MFS-transporter
MSPLNINKNNWRALIAAIVASGTDDLNIMFLAFSMSTIITDLHLSAAQAGWIGTITNLGMLVGGLIFGLLADRYNKFKVFKWTILIFSIATGLVFFTTNLSYLYIMRFIAGIGVGGEYGIAIAIMAGIVPANKMGRISSLNGIAGQVGSISSALLAGWLAPALGWRGLFLFGLLPIVLVLWMQFAIDDKDILDQYNTDADDEPLDISIKALFDTPVLATQSLALMVMTTVQIAGYFGMMNWLPTIIQTNLNVSVKNSSLWMIATIFGMCLGMLVFGQLLDKFGPRLVYGCFLLSSAICVYLFQFATTMPSMIIGGAVVGFFVNGMFAGYGAMITRLYPHHIRSTANNLILNVGRAIGGFSSVIIGMILDVSNVSMVMLFLASLYIVSFLSMLSIKQLKRQKYHTNLTQLDVKPTD
>NZ_CP021773.1|WP_071659995.1|2219355_2220522_-|IS30-like-element-ISSag9-family-transposase
MTKHKHLTLSDRNDIQSGLDRGETFKAIGLNLLKHPTTIAKEVKRNKQLRESTKDCLDCPLLRKATYVCNGCPKRRINCGYKKTFYLAKQAQRNYEKLLVESREGIPLNKETFWKIDRVLSNGVKKGQRIYHILKTNDLEVSSSTVYRHIKKGYLSITPIDLPRAVKFKKRRKSTLPPIPKAIKEGRRYEDFIEHMNQSELNSWLEMDTVIGRIGGKVLLTFNVAFCNFIFAKLMDSKTAIETAKHIQVIKRTLYDNKRDFFELFPVILTDNGGEFARVDDIEIDVCGQSQLFFCDPNRSDQKARIEKNHTLVRDILPKGTSFDNLTQEDINLALSHINSVKRQALNGKTAYELFSFTYGKDIASILGIEEITAEDVCQSPKLLKDKI
>NZ_CP021773.1|WP_000145176.1|2220737_2223239_+|leucine--tRNA-ligase
MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIKGKVKAKLVVAKDLSREELQEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK
>NZ_CP021773.1|WP_000903266.1|2223328_2223937_-|hypothetical-protein
MLHSKKIHSLSLIAVLSLATYTSLQPNHVAAEQSQKTSTVHMSQKTIEHKLKVADKEAAPLYAKIDHIQRHIEVKKAKDLKVIELYINKDINQLEKQNKRLLTKFYTSIDNQTWDSTSEVKKLIDKTTLSTNEKDRLKLYFEQRAYLETRLNDRYQKFDNSIENQNKELKILTSKIEKIYQKHGITKEVLKTYYAKKTVRAD
>NZ_CP021773.1|WP_000730410.1|2224029_2225418_-|HAMP-domain-containing-histidine-kinase
MKKKSLISNLILINSITLFLGFYLIYFSVNYVIKDYVHQMTRNSMQANFTILDSIYNNKKIPDENMVNQDSIFVWSYYAIFDQHYRMKYGTDNHKKESHDIIRYLTQKRLWQISKEKDGMFITIKKKTYYVMTKDYSGILVDGSIKKAPKAQSQLFHVINFSDITYTQHLITKINHFLIVILVLTYIPMLFIMRKTFTGIRESIQSVQTYISSLWKNQGNHQSSQKEIVFSDFDPLLLESQEMANRIYQAEESQRNFFQNASHELRTPLMSIQGYTEGVQEGIIDAELAHSVILQESKKMKQLVDDIILLSKLDSNLSDQKDEFSLNELLNSIIAYFKPLANKQKISITYRPDKHEKLLKGNEELIQRAINNILSNALRYAVSHIEISYTNQKLTISNDGPAISKEDLPYIFDRFYKGHGGQTGIGLAMTKEIIKQHHGNIIAESDSTSTTFTIYFNCHKIA
>NZ_CP021773.1|WP_001093377.1|2226332_2231048_-|S8-family-serine-peptidase
MNTKQRFSIRKYKLGAVSVLLGTLFFLGGITNVAADSVINKPSDIAVEQQVKDSPTSIANETPTNNTSSALASTAQDNLVTKANNNSPTETQPVTEPHSQATETFSPAANQPVESTQEVSKTPLTKQNLAVKPTPAISKETPQNIDSNKIITVPKVWNTGYKGEGTVVAIIDSGLDTNHDALQLNDSTKAKYQNEQQMNAAKAKAGINYGKWYNNKVIFGHNYVDVNTELKEVKSTSHGMHVTSIATANPSKKDTNELIYGVAPEAQVMFMRVFSDEKRGTGPALYVKAIEDAVKLGADSINLSLGGANGSLVNADDRLIKALEMARLAGVSVVIAAGNDGTFGSGASKPSALYPDYGLVGSPSTAREAISVASYNNTTLVNKVFNIIGLENNKNLNNGLAAYADPKVSDKTFEVGKQYDYVFVGKGNDNDYKDKTLNGKIALIERGDITFTKKVVNAINHGAVGAIIFNNKAGEANLTMSLDPEASAIPAIFTQKEFGDVLAKNNYKIVFNNIKNKQANPNAGVLSDFSSWGLTADGQLKPDLSAPGGSIYAAINDNEYDMMSGTSMASPHVAGATALVKQYLLKEHPELKKGDIERTVKYLLMSTAKAHLNKDTGAYTSPRQQGAGIIDVAAAVQTGLYLTGGENNYGSVTLGNIKDKISFDVTVHNINKVAKDLHYTTYLNTDQVKDGFVTLAPQQLGTFTGKTIRIEPGQTKTITIDIDVSKYHDMLKKVMPNGYFLEGYVRFTDPVDGGEVLSIPYVGFKGEFQNLEVLEKSIYKLVANKEKGFYFQPKQTNEVPGSEDYTALMTTSSEPIYSTDGTSPIQLKALGSYKSIDGKWILQLEQKGQPHLAISPNDDQNQDAVALKGVFLRNFNNLRAKVYRADDVNLQKPLWVSAPQAGDKNYYSGNTENPKSTFLYDTEWKGTTTDGIPLEDGKYKYVLTYYSDVPGSKPQQMVFDITLDRQAPTLTTATYDKDRRIFKARPAVEHGESGIFREQVFYLKKDKDGHYNSVLRQKGEDGILVEDNKVFIKQEKDGSFILPKEVNDFSHVYYTVEDYAGNLVSAKLEDLINIGNKNGLVNVKVFSPELNSNVDIDFSYSVKDDKGNVIKKQHHGKDLNLLKLPFGTYTFDLFLYDEERANLISPQSVTVTISEKDSLKDVLFKVNLLKKAALLVEFDKLLPKGATVQLVTKTNTVVDLPKATYSPTDYGKNIPVGDYRLNVTLPSGYSTLENLDDLLVSVKEGQVNLTKLTLINKAPLINALAEQTDIISQPVFYNAGTHLKNNYLANLEKAQTLIKNRVEQTSIDNAIAALRESRQALNGKETDTSLLAKAILAETEIKGNYQFVNASPLSQSTYINQVQLAKNLLQKPNVTQSEVDKALENLDIAKNQLNGHETDYSGLHHMIIKANVLKQTSSKYQNASQFAKENYNNLIKKAELLLSNRQATQAQVEELLNQIKATEQELDGRDRVSSAENYSQSLNDNDSLNTTPINPPNQPQALIFKKGMTKESEVAQKRVLGVTSQTDNQKIKTNKLPKTGESTPKITYTILLFSLSMLGLATIKLKSIKRE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021773_1	1.2\|1083375\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448971	Streptococcus phage Javan52, complete genome	25346-25375	0	1.0
NZ_CP021773_1	1.2\|1083375\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448956	Streptococcus phage Javan48, complete genome	23665-23694	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448796	Streptococcus phage Javan53, complete genome	38135-38164	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448971	Streptococcus phage Javan52, complete genome	34320-34349	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448736	Streptococcus phage Javan35, complete genome	29484-29513	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448956	Streptococcus phage Javan48, complete genome	32639-32668	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448781	Streptococcus phage Javan5, complete genome	31506-31535	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448938	Streptococcus phage Javan44, complete genome	29485-29514	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448911	Streptococcus phage Javan34, complete genome	29484-29513	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448837	Streptococcus phage Javan10, complete genome	27542-27571	0	1.0
NZ_CP021773_1	1.3\|1083441\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448916	Streptococcus phage Javan36, complete genome	29484-29513	0	1.0
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	MH853356	Streptococcus phage LF2, partial genome	36955-36984	0	1.0
NZ_CP021773_1	1.8\|1083771\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083771-1083800	30	MK448956	Streptococcus phage Javan48, complete genome	33978-34007	0	1.0
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448871	Streptococcus phage Javan196, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448952	Streptococcus phage Javan472, complete genome	36830-36859	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448775	Streptococcus phage Javan489, complete genome	38943-38972	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448961	Streptococcus phage Javan494, complete genome	36338-36367	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448970	Streptococcus phage Javan516, complete genome	42552-42581	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448697	Streptococcus phage Javan185, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448953	Streptococcus phage Javan474, complete genome	40664-40693	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448693	Streptococcus phage Javan177, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448945	Streptococcus phage Javan454, complete genome	36499-36528	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448766	Streptococcus phage Javan465, complete genome	37195-37224	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448696	Streptococcus phage Javan183, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448868	Streptococcus phage Javan188, complete genome	37400-37429	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448866	Streptococcus phage Javan184, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448851	Streptococcus phage Javan14, complete genome	39043-39072	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448699	Streptococcus phage Javan189, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448867	Streptococcus phage Javan186, complete genome	37399-37428	1	0.967
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	MK448749	Streptococcus phage Javan39, complete genome	26022-26051	1	0.967
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448796	Streptococcus phage Javan53, complete genome	44973-45002	2	0.933
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MK448956	Streptococcus phage Javan48, complete genome	38085-38114	2	0.933
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	MK448694	Streptococcus phage Javan179, complete genome	25046-25075	2	0.933
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	JX409894	Streptococcus phage LYGO9, complete genome	22367-22396	3	0.9
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	JX409895	Streptococcus phage JX01, complete genome	34214-34243	3	0.9
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	KT337358	Streptococcus phage phiARI0468-4, complete genome	28300-28329	4	0.867
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	NC_022791	Streptococcus phage phiBHN167 complete genome	23705-23734	4	0.867
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	MK448898	Streptococcus phage Javan284, complete genome	8520-8549	4	0.867
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	KY065502	Streptococcus phage IPP66, complete genome	7847-7876	4	0.867
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	MT900488	Streptococcus phage SA01, complete genome	8543-8572	4	0.867
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	AJ490330	Bacteriophage VO1 ORF1 and met gene for putative C5-methylase	736-765	4	0.867
NZ_CP021773_1	1.4\|1083507\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	KY065456	Streptococcus phage IPP15, complete genome	9104-9133	4	0.867
NZ_CP021773_1	1.2\|1083375\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448851	Streptococcus phage Javan14, complete genome	24320-24349	5	0.833
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	NZ_CP014491	Escherichia coli strain G749 plasmid pG749_3, complete sequence	41416-41445	6	0.8
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	NC_041936	Escherichia phage ECD7, complete genome	82144-82173	6	0.8
NZ_CP021773_1	1.2\|1083375\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	NC_019691	Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence	26157-26186	6	0.8
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	135471-135500	7	0.767
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	CP015514	Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence	858564-858593	7	0.767
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	MG945249	UNVERIFIED: Microviridae sp. isolate 2447-1602, partial genome	2309-2338	7	0.767
NZ_CP021773_1	1.2\|1083375\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448821	Streptococcus phage Javan623, complete genome	20349-20378	7	0.767
NZ_CP021773_1	1.2\|1083375\|30\|NZ_CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448822	Streptococcus phage Javan629, complete genome	23253-23282	7	0.767
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	NZ_CP047439	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence	37036-37065	7	0.767
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	NZ_CP047440	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence	62197-62226	7	0.767
NZ_CP021773_1	1.6\|1083639\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083639-1083668	30	NZ_CP026738	Bacillus megaterium strain YC4-R4 plasmid unnamed2	132906-132935	7	0.767
NZ_CP021773_1	1.6\|1083639\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083639-1083668	30	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	38202-38231	7	0.767
NZ_CP021773_1	1.7\|1083705\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083705-1083734	30	NC_015937	Thermus phage TMA, complete genome	108316-108345	7	0.767
NZ_CP021773_1	1.7\|1083705\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083705-1083734	30	MH595538	Vibrio phage BONAISHI, complete genome	251052-251081	7	0.767
NZ_CP021773_1	1.7\|1083705\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083705-1083734	30	AP011617	Thermus phage TMA DNA, complete genome	108316-108345	7	0.767
NZ_CP021773_1	1.1\|1083309\|30\|NZ_CP021773\|CRT	1083309-1083338	30	NC_022883	Enterococcus mundtii QU 25 plasmid pQY082, complete sequence	57911-57940	8	0.733
NZ_CP021773_1	1.5\|1083573\|30\|NZ_CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	NZ_CP021745	Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence	124621-124650	8	0.733
NZ_CP021773_2	2.2\|2212979\|30\|NZ_CP021773\|CRT	2212979-2213008	30	MN855875	Bacteriophage sp. isolate 328, complete genome	1401-1430	8	0.733
NZ_CP021773_1	1.8\|1083771\|30\|NZ_CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083771-1083800	30	NZ_CP023038	Komagataeibacter saccharivorans strain CV1 plasmid unnamed2, complete sequence	114479-114508	9	0.7

1. spacer 1.2|1083375|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccactttttatc	Protospacer
******************************

2. spacer 1.2|1083375|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccactttttatc	Protospacer
******************************

3. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

4. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

5. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

6. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

7. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

8. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

9. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

10. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

11. spacer 1.3|1083441|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

12. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tacctggaatgttaaatttaccttttagca	Protospacer
******************************

13. spacer 1.8|1083771|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

tttacattaaaaaaatggacgagcggtcaa	CRISPR spacer
tttacattaaaaaaatggacgagcggtcaa	Protospacer
******************************

14. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

15. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

16. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

17. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448961 (Streptococcus phage Javan494, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

18. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

19. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

20. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

21. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

22. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

23. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

24. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

25. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

26. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

27. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

28. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

29. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

30. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 1, identity: 0.967

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tgcctggaatgttaaatttaccttttagca	Protospacer
*.****************************

31. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 2, identity: 0.933

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acataccaggaatataaaagtcgttcaaat	Protospacer
*****.*************.**********

32. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 2, identity: 0.933

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acataccaggaatataaaagtcgttcaaat	Protospacer
*****.*************.**********

33. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 2, identity: 0.933

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tacccggaatgttaaacttaccttttagca	Protospacer
****.***********.*************

34. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 3, identity: 0.9

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tgccaggaatgttaaatttaccttttaaca	Protospacer
*.** **********************.**

35. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 3, identity: 0.9

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tgccaggaatgttaaatttaccttttaaca	Protospacer
*.** **********************.**

36. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to KT337358 (Streptococcus phage phiARI0468-4, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

37. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to NC_022791 (Streptococcus phage phiBHN167 complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

38. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448898 (Streptococcus phage Javan284, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgaaccgttaccgctatcgaaaa	Protospacer
* ******** **************.** *

39. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to KY065502 (Streptococcus phage IPP66, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

40. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MT900488 (Streptococcus phage SA01, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

41. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to AJ490330 (Bacteriophage VO1 ORF1 and met gene for putative C5-methylase) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

42. spacer 1.4|1083507|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to KY065456 (Streptococcus phage IPP15, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

43. spacer 1.2|1083375|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 5, identity: 0.833

tgccttttaattcagctcccactttttatc	CRISPR spacer
ctccttttaattcagcacccattttttaac	Protospacer
. ************** ****.****** *

44. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to NZ_CP014491 (Escherichia coli strain G749 plasmid pG749_3, complete sequence) position: , mismatch: 6, identity: 0.8

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
gcatatcaggaatataaaaatcataaagag	Protospacer
.*********************.*  *.*

45. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to NC_041936 (Escherichia phage ECD7, complete genome) position: , mismatch: 6, identity: 0.8

acatatcaggaatataaaaatcgttcaaat-	CRISPR spacer
gcatatcaggaatattaaaattg-tcacctg	Protospacer
.************** *****.* ***  *

46. spacer 1.2|1083375|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to NC_019691 (Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence) position: , mismatch: 6, identity: 0.8

tgccttttaattcagctcccactttttatc	CRISPR spacer
ctccttttaattcagcttccactttatcta	Protospacer
. ***************.******* * *

47. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 7, identity: 0.767

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
gaatatcaggaatataaaaatttttcccaa	Protospacer
. *******************. ***  *

48. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to CP015514 (Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
ccagatcaggaatataaatatcgttacctt	Protospacer
 ** ************** ******    *

49. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to MG945249 (UNVERIFIED: Microviridae sp. isolate 2447-1602, partial genome) position: , mismatch: 7, identity: 0.767

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaagaatataaaaatcttgagcaa	Protospacer
********.************* *  . *

50. spacer 1.2|1083375|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448821 (Streptococcus phage Javan623, complete genome) position: , mismatch: 7, identity: 0.767

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccatactaacta	Protospacer
*********************. .*   *

51. spacer 1.2|1083375|30|NZ_CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448822 (Streptococcus phage Javan629, complete genome) position: , mismatch: 7, identity: 0.767

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccatactaacta	Protospacer
*********************. .*   *

52. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to NZ_CP047439 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence) position: , mismatch: 7, identity: 0.767

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tatttggaatgtttaatttatcttttactt	Protospacer
**..********* ******.****** .

53. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to NZ_CP047440 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence) position: , mismatch: 7, identity: 0.767

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tatttggaatgtttaatttatcttttactt	Protospacer
**..********* ******.****** .

54. spacer 1.6|1083639|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP026738 (Bacillus megaterium strain YC4-R4 plasmid unnamed2) position: , mismatch: 7, identity: 0.767

atgttgccactagttgctctttatgaacag	CRISPR spacer
tcgctctgactagttgctctttatgaacaa	Protospacer
 .*.* . *********************.

55. spacer 1.6|1083639|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 7, identity: 0.767

atgttgccactagttgctctttatgaacag	CRISPR spacer
tcgctctgactagttgctctttatgaacaa	Protospacer
 .*.* . *********************.

56. spacer 1.7|1083705|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NC_015937 (Thermus phage TMA, complete genome) position: , mismatch: 7, identity: 0.767

agtttcttttaagttcaatgtttgtcaaat----	CRISPR spacer
agtttcttttgagtttaatgttt----tattctg	Protospacer
**********.****.*******     **

57. spacer 1.7|1083705|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to MH595538 (Vibrio phage BONAISHI, complete genome) position: , mismatch: 7, identity: 0.767

agtttcttttaagttcaatgtttgtcaaat	CRISPR spacer
tgtttcctttatgttcaatgtttgccttaa	Protospacer
 *****.**** ************.*  *

58. spacer 1.7|1083705|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to AP011617 (Thermus phage TMA DNA, complete genome) position: , mismatch: 7, identity: 0.767

agtttcttttaagttcaatgtttgtcaaat----	CRISPR spacer
agtttcttttgagtttaatgttt----tattctg	Protospacer
**********.****.*******     **

59. spacer 1.1|1083309|30|NZ_CP021773|CRT matches to NC_022883 (Enterococcus mundtii QU 25 plasmid pQY082, complete sequence) position: , mismatch: 8, identity: 0.733

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
ccccttcaggaatatagaaatcattcaata	Protospacer
 * . ***********.*****.*****

60. spacer 1.5|1083573|30|NZ_CP021773|CRT,CRISPRCasFinder matches to NZ_CP021745 (Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence) position: , mismatch: 8, identity: 0.733

tacctggaatgttaaatttaccttttagca	CRISPR spacer
cttggagaaggttaaatttaccttatagca	Protospacer
. .  .*** ************** *****

61. spacer 2.2|2212979|30|NZ_CP021773|CRT matches to MN855875 (Bacteriophage sp. isolate 328, complete genome) position: , mismatch: 8, identity: 0.733

ttaaaccagacgttaagccagaggccaaac	CRISPR spacer
atggcgcagacgttgagccagaggccactc	Protospacer
 *..  ********.************  *

62. spacer 1.8|1083771|30|NZ_CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP023038 (Komagataeibacter saccharivorans strain CV1 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

tttacattaaaaaaatggacgagcggtcaa	CRISPR spacer
gacagattaaaaaaatggccgagcggattg	Protospacer
  .* ************* ******* . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

372791 : 385050

Streptococcus_phage(83.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001185987.1\|372791_373616_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-14	23.6
WP_000178147.1\|373554_374265_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.2e-17	28.1
WP_001144245.1\|374283_374943_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.0
WP_000160598.1\|375207_376374_-\|transposase	IS30-like element ISSag9 family transposase	NA	NA	NA	NA
WP_000715592.1\|376582_377218_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_000364562.1\|377237_378101_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.1e-72	49.0
WP_000358198.1\|378130_378457_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_000425856.1\|378456_379326_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.9e-110	70.4
WP_000603277.1\|379595_380231_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_000587955.1\|380363_381455_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.3e-163	77.1
WP_001167085.1\|381522_382071_+	acetyltransferase	M1PSC3	Streptococcus_phage	1.1e-54	58.4
WP_000966772.1\|383348_383825_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	7.1e-39	50.9
WP_000287943.1\|383826_384183_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
WP_000767484.1\|384222_385050_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	4.3e-124	78.0

DBSCAN-SWA_2

653609 : 724765

Streptococcus_phage(38.1%)

integrase,protease,transposase

attL 709016:709031|attR 718775:718790

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000826253.1\|653609_654191_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000093689.1\|654267_654756_+	hypothetical protein	NA	NA	NA	NA
WP_000253516.1\|654755_656576_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_001072180.1\|656593_656836_+	hypothetical protein	NA	NA	NA	NA
WP_001066427.1\|656852_657707_+	conjugal transfer protein TrbL	NA	NA	NA	NA
WP_001097594.1\|657768_658122_+	PrgI family protein	NA	NA	NA	NA
WP_002921334.1\|658078_660430_+	ATPase AAA	NA	NA	NA	NA
WP_071659950.1\|660426_663231_+	CHAP domain-containing protein	NA	NA	NA	NA
WP_001012715.1\|663475_664069_+	hypothetical protein	NA	NA	NA	NA
WP_032461792.1\|664312_669217_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_000433422.1\|669217_669409_+	hypothetical protein	NA	NA	NA	NA
WP_000312517.1\|669392_669944_+	hypothetical protein	NA	NA	NA	NA
WP_071659951.1\|669993_675453_+	DEAD/DEAH box helicase family protein	A0A248SL14	Klebsiella_phage	8.2e-147	30.5
WP_001258309.1\|675950_677729_+	hypothetical protein	A0A0U4J920	Pseudomonas_phage	8.9e-26	28.6
WP_079865947.1\|677866_679210_+	helicase	H2DE57	Erwinia_phage	2.1e-56	32.5
WP_000195243.1\|679279_679579_+	hypothetical protein	NA	NA	NA	NA
WP_000572502.1\|679593_679884_+	hypothetical protein	NA	NA	NA	NA
WP_000932867.1\|679994_680633_+	hypothetical protein	NA	NA	NA	NA
WP_000196745.1\|680672_681761_+	DUF3991 domain-containing protein	NA	NA	NA	NA
WP_000110927.1\|681814_682030_+	hypothetical protein	NA	NA	NA	NA
WP_000159227.1\|682045_682441_+	hypothetical protein	NA	NA	NA	NA
WP_001235982.1\|682484_682772_+	hypothetical protein	NA	NA	NA	NA
WP_001072431.1\|682798_683098_-	hypothetical protein	M1PG86	Streptococcus_phage	1.5e-26	59.6
WP_000567221.1\|683084_683453_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	3.7e-35	63.1
WP_071659986.1\|683449_684865_-	Y-family DNA polymerase	M1Q231	Streptococcus_phage	1.1e-215	78.1
WP_000491222.1\|685006_685699_-	helix-turn-helix transcriptional regulator	A0A1B0RXB1	Streptococcus_phage	6.0e-95	74.2
WP_106083840.1\|687722_688834_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	6.1e-49	41.1
WP_106083844.1\|688903_689653_+	ATP-binding protein	A0A1B1IUG5	uncultured_Mediterranean_phage	4.2e-09	29.0
WP_000529539.1\|690071_690431_+	hypothetical protein	NA	NA	NA	NA
WP_000263053.1\|690440_690806_+	MobC family plasmid mobilization relaxosome protein	NA	NA	NA	NA
WP_000261800.1\|690792_692655_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_000873143.1\|693435_693606_+	hypothetical protein	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2
WP_000417519.1\|693991_695209_+	macrolide efflux MFS transporter Mef(A)	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
WP_000420313.1\|695328_696792_+	ABC-F type ribosomal protection protein Msr(D)	A0A1B0RXA0	Streptococcus_phage	3.7e-251	97.3
WP_000567222.1\|697194_697563_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
WP_071659982.1\|697575_697911_-	imsC-like protein	NA	NA	NA	NA
WP_001813542.1\|697907_698153_-	hypothetical protein	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
WP_000142891.1\|699117_699588_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000845068.1\|699571_700597_+	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
WP_071659983.1\|700593_702339_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.3e-37	25.6
WP_071659984.1\|702319_704059_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	5.1e-18	28.1
WP_000482660.1\|704455_704950_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_000278092.1\|707031_707250_+	helix-turn-helix transcriptional regulator	A0A1L2BY72	Clostridium_phage	2.7e-09	52.5
WP_002921272.1\|707520_707769_+	DUF3173 family protein	NA	NA	NA	NA
WP_000201883.1\|707771_708977_+\|integrase	site-specific integrase	U3PJ31	Staphylococcus_phage	2.6e-08	21.4
709016:709031	attL	NA	NA	NA	NA
WP_000835391.1\|709325_710327_+	DNA cytosine methyltransferase	F2Y148	Organic_Lake_phycodnavirus	2.5e-81	47.0
WP_000264509.1\|710327_711137_+	Eco47II family restriction endonuclease	NA	NA	NA	NA
WP_000626555.1\|711194_712391_+	protein kinase family protein	A0A1V0SBL0	Catovirus	4.5e-13	38.0
WP_000589504.1\|712444_713605_-	hypothetical protein	NA	NA	NA	NA
WP_000723565.1\|714385_714811_+	hypothetical protein	NA	NA	NA	NA
WP_050295494.1\|714885_716292_+	cell division protein FtsK	NA	NA	NA	NA
WP_000200242.1\|716393_717263_+	hypothetical protein	NA	NA	NA	NA
WP_000487305.1\|717240_717540_+	DUF3173 family protein	NA	NA	NA	NA
WP_000157135.1\|717542_718745_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_000248015.1\|718924_720160_-	hypothetical protein	NA	NA	NA	NA
718775:718790	attR	NA	NA	NA	NA
WP_088197863.1\|720284_721390_-\|transposase	IS3-like element ISSag2 family transposase	A0A2I7SC85	Paenibacillus_phage	6.3e-70	48.9
WP_000863581.1\|722447_722678_+	hypothetical protein	NA	NA	NA	NA
WP_000584204.1\|722774_723323_+	hypothetical protein	NA	NA	NA	NA
WP_000453221.1\|723430_724765_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1245265 : 1347227

Streptococcus_phage(70.59%)

tail,terminase,protease,tRNA,holin,head,portal,transposase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000038843.1\|1245265_1245739_+\|tRNA	aminoacyl-tRNA deacylase	NA	NA	NA	NA
WP_000675286.1\|1245760_1246402_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_000633103.1\|1246437_1247340_-	HAD family hydrolase	NA	NA	NA	NA
WP_000070706.1\|1247514_1249005_+\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	7.6e-87	38.5
WP_000152414.1\|1249079_1249550_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.3e-40	52.7
WP_000885813.1\|1249564_1250758_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.5e-111	51.0
WP_000493863.1\|1250775_1251426_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.6e-35	39.9
WP_000975997.1\|1251406_1252516_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	1.2e-55	37.2
WP_001073012.1\|1253243_1254584_+	divalent metal cation transporter	NA	NA	NA	NA
WP_000618020.1\|1254685_1255483_-	hypothetical protein	NA	NA	NA	NA
WP_001288869.1\|1255606_1255819_-	hypothetical protein	NA	NA	NA	NA
WP_000073158.1\|1255945_1257232_-	U32 family peptidase	Q6DW11	Phage_TP	1.9e-41	32.4
WP_000411251.1\|1257361_1258288_-	U32 family peptidase	NA	NA	NA	NA
WP_000097985.1\|1258630_1258906_+	DUF3270 domain-containing protein	NA	NA	NA	NA
WP_000039971.1\|1258946_1259378_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_000569599.1\|1259374_1259773_-	DUF948 domain-containing protein	NA	NA	NA	NA
WP_000609726.1\|1259787_1260561_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_000301753.1\|1260553_1261489_-	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_000842478.1\|1261716_1261980_-	PspC domain-containing protein	NA	NA	NA	NA
WP_000366647.1\|1262060_1262519_-	SprT family protein	U5J9G1	Bacillus_phage	1.7e-05	26.3
WP_000429380.1\|1262481_1264644_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_000571055.1\|1264747_1265791_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_001018624.1\|1265923_1266052_+	hypothetical protein	NA	NA	NA	NA
WP_000350891.1\|1266057_1266960_+	permease	NA	NA	NA	NA
WP_000617815.1\|1266959_1267772_+	TIGR03943 family protein	NA	NA	NA	NA
WP_112409707.1\|1269664_1271242_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_000884197.1\|1271241_1272066_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_047020691.1\|1272065_1272863_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_017646703.1\|1272982_1274548_-	recombinase family protein	Q6DMS5	Streptococcus_phage	8.0e-180	61.5
WP_017646702.1\|1274550_1275759_-	recombinase family protein	Q6DMS6	Streptococcus_phage	1.8e-102	49.7
WP_017646701.1\|1275973_1276375_-	DNA-directed RNA polymerase sigma-70 factor	NA	NA	NA	NA
WP_017646700.1\|1276484_1277954_-	LysM peptidoglycan-binding domain-containing protein	A0A1X9I678	Streptococcus_phage	1.8e-226	78.9
WP_017646699.1\|1277955_1278360_-\|holin	phage holin family protein	D0R0E9	Streptococcus_phage	3.0e-46	74.8
WP_017646698.1\|1278377_1280234_-	hypothetical protein	Q6DMS9	Streptococcus_phage	2.5e-257	73.3
WP_017646697.1\|1280246_1283162_-	carbamoylsarcosine amidase	Q6DMT0	Streptococcus_phage	0.0e+00	64.8
WP_017646696.1\|1283161_1283887_-\|tail	phage tail protein	Q6DMT1	Streptococcus_phage	1.4e-81	57.9
WP_017646695.1\|1283883_1287003_-	hypothetical protein	Q6DMT2	Streptococcus_phage	2.0e-254	76.7
WP_001249611.1\|1287185_1287605_-	hypothetical protein	A0A1X9I691	Streptococcus_phage	1.3e-55	76.3
WP_017646694.1\|1287616_1288186_-\|tail	phage tail protein	A0A1B0RXE2	Streptococcus_phage	1.5e-96	93.6
WP_017646693.1\|1288188_1288515_-	hypothetical protein	M1Q1Z4	Streptococcus_phage	8.3e-39	69.4
WP_017646692.1\|1288523_1288892_-	hypothetical protein	Q6DMT7	Streptococcus_phage	7.0e-34	62.9
WP_017646691.1\|1288884_1289223_-\|head,tail	head-tail adaptor protein	A0A1B0RXJ6	Streptococcus_phage	4.3e-38	70.5
WP_017646690.1\|1289222_1289480_-\|head,tail	phage gp6-like head-tail connector protein	D0R0D7	Streptococcus_phage	9.5e-30	78.8
WP_017646689.1\|1289476_1290685_-\|capsid	phage major capsid protein	E4ZFM5	Streptococcus_phage	1.0e-211	91.3
WP_017646688.1\|1290697_1291396_-\|protease	Clp protease ClpP	A0A1B0RXE1	Streptococcus_phage	5.8e-106	83.6
WP_017646687.1\|1291388_1292684_-\|portal	phage portal protein	A0A1B0RXD8	Streptococcus_phage	8.0e-226	89.3
WP_017646686.1\|1292752_1292956_-	hypothetical protein	NA	NA	NA	NA
WP_017646685.1\|1293025_1293364_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_017646684.1\|1293356_1293650_-	hypothetical protein	NA	NA	NA	NA
WP_017646683.1\|1293716_1295309_-\|terminase	terminase large subunit	A0A1B0RXJ8	Streptococcus_phage	6.0e-308	95.8
WP_017646682.1\|1295305_1295779_-\|terminase	phage terminase small subunit P27 family	A0A1X9I6K0	Streptococcus_phage	1.5e-84	96.8
WP_017646681.1\|1295827_1296277_-	DUF4314 domain-containing protein	A0A1X9I6A3	Streptococcus_phage	4.1e-20	67.1
WP_017646680.1\|1296278_1296530_-	hypothetical protein	M1PG57	Streptococcus_phage	5.8e-16	59.3
WP_017646679.1\|1296591_1297872_-	DNA (cytosine-5-)-methyltransferase	M1NSK8	Streptococcus_phage	2.2e-231	92.3
WP_017646678.1\|1297868_1299125_-	DNA modification methylase	A0A1B0RXE5	Streptococcus_phage	3.0e-225	90.9
WP_017646677.1\|1299096_1299552_-	hypothetical protein	M1Q209	Streptococcus_phage	1.0e-42	50.3
WP_017646676.1\|1299840_1300206_-	HNH endonuclease	A0A1B0RXJ3	Streptococcus_phage	3.2e-63	88.4
WP_083308032.1\|1300207_1300384_-	methionine adenosyltransferase domain-containing protein	D0R0C1	Streptococcus_phage	4.7e-20	74.1
WP_017646674.1\|1301292_1301475_-	hypothetical protein	A0A1B0RXC3	Streptococcus_phage	1.7e-20	86.7
WP_017646673.1\|1301669_1302146_-	hypothetical protein	A0A1B0RXB9	Streptococcus_phage	3.2e-71	84.2
WP_017646672.1\|1302138_1303515_-	DEAD/DEAH box helicase	A0A1X9I6B0	Streptococcus_phage	1.6e-232	86.7
WP_112409708.1\|1303495_1303777_-	VRR-NUC domain-containing protein	M1PFY8	Streptococcus_phage	1.1e-39	83.9
WP_017646670.1\|1304057_1306346_-	hypothetical protein	A0A1B0RXC5	Streptococcus_phage	0.0e+00	87.9
WP_017646668.1\|1306704_1307028_+	hypothetical protein	D0R0B4	Streptococcus_phage	8.8e-33	72.9
WP_017646667.1\|1307020_1308142_+	DUF2800 domain-containing protein	M1Q218	Streptococcus_phage	3.5e-201	90.9
WP_017646666.1\|1308146_1308710_+	DUF2815 family protein	A0A1B0RXA9	Streptococcus_phage	1.5e-91	92.8
WP_071659977.1\|1308944_1310900_+	DNA polymerase	E4ZFK1	Streptococcus_phage	0.0e+00	86.0
WP_017646663.1\|1310961_1311504_-	hypothetical protein	NA	NA	NA	NA
WP_017646662.1\|1311665_1312262_-	hypothetical protein	A0A1B0RXB3	Streptococcus_phage	4.6e-11	27.9
WP_003047226.1\|1312694_1313819_+	hypothetical protein	NA	NA	NA	NA
WP_001176802.1\|1313818_1314043_+	hypothetical protein	NA	NA	NA	NA
WP_000904398.1\|1314033_1315692_+	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_000673009.1\|1315681_1315891_+	helix-turn-helix domain-containing protein	A0A2K5B263	Erysipelothrix_phage	4.8e-16	58.5
WP_000154547.1\|1316149_1316500_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_000391861.1\|1316553_1316739_+\|transposase	transposase	NA	NA	NA	NA
WP_071659975.1\|1316710_1317982_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_003043792.1\|1325824_1327075_+	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
WP_000593525.1\|1327383_1328016_+	hypothetical protein	NA	NA	NA	NA
WP_003047216.1\|1328583_1329885_-	hypothetical protein	NA	NA	NA	NA
WP_003047214.1\|1330141_1330660_-	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_000478786.1\|1331538_1335078_-	chromosome segregation protein SMC	NA	NA	NA	NA
WP_000661526.1\|1335085_1335772_-	ribonuclease III	A0A167RGU4	Powai_lake_megavirus	3.3e-21	29.9
WP_000719384.1\|1335946_1336315_-	YbaN family protein	NA	NA	NA	NA
WP_001289498.1\|1336317_1337127_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	2.5e-39	37.6
WP_001065465.1\|1337130_1338480_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	2.7e-35	33.8
WP_000722052.1\|1338472_1339183_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.1e-38	38.5
WP_000053146.1\|1339522_1340278_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.6e-38	41.7
WP_000946173.1\|1340289_1341090_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_000173638.1\|1341102_1341798_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000100034.1\|1341809_1342460_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000592389.1\|1342508_1343075_-	peptidase	NA	NA	NA	NA
WP_001140268.1\|1343241_1344261_-	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_001261246.1\|1344358_1345063_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-31	33.6
WP_000591006.1\|1345283_1347227_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	7.5e-119	37.9

DBSCAN-SWA_4

1434172 : 1444732

Streptococcus_phage(91.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001255868.1\|1434172_1435039_-	aminoglycoside 6-adenylyltransferase AadE	E4ZFP8	Streptococcus_phage	7.5e-103	63.7
WP_001071501.1\|1435214_1435760_-	AAA family ATPase	NA	NA	NA	NA
WP_001284310.1\|1435811_1435970_-	hypothetical protein	NA	NA	NA	NA
WP_000301765.1\|1435971_1436244_-	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.0e-05	100.0
WP_000260238.1\|1436261_1436477_-	omega protein	A0A1X9I6D5	Streptococcus_phage	4.2e-31	97.1
WP_000409924.1\|1436568_1437423_-	ParA family protein	A0A1X9I765	Streptococcus_phage	4.1e-154	99.3
WP_073459356.1\|1437553_1437838_-	topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.3e-40	93.0
WP_001038790.1\|1437983_1438721_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_001814874.1\|1438845_1438929_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_001096887.1\|1439470_1440265_-	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_088186165.1\|1440767_1441930_-\|transposase	IS3-like element ISSag12 family transposase	A0A2I7SC85	Paenibacillus_phage	9.2e-80	53.7
WP_044116541.1\|1442003_1442210_-	hypothetical protein	A0A1B0RXL7	Streptococcus_phage	4.8e-24	100.0
WP_001255866.1\|1442206_1443115_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
WP_000662263.1\|1443147_1443882_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_000233000.1\|1443862_1444732_-	hypothetical protein	A0A1X9I6C9	Streptococcus_phage	6.7e-152	90.7

DBSCAN-SWA_5

1452346 : 1467874

Streptococcus_phage(53.85%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002294507.1\|1452346_1452874_-	adenine phosphoribosyltransferase	A0A1X9I6E2	Streptococcus_phage	1.9e-93	100.0
WP_002294505.1\|1452917_1453781_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	A0A1X9I6F2	Streptococcus_phage	8.7e-168	100.0
WP_000662263.1\|1453813_1454548_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_071661597.1\|1454528_1455398_-	hypothetical protein	A0A1X9I6C9	Streptococcus_phage	1.2e-153	92.0
WP_000205227.1\|1455412_1455637_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_071659949.1\|1455779_1457324_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	2.3e-256	88.7
WP_000323438.1\|1457343_1457760_-	recombinase	A0A2K5B2B3	Erysipelothrix_phage	1.2e-71	98.6
WP_002360685.1\|1457760_1458057_-	hypothetical protein	A0A2K5B2B2	Erysipelothrix_phage	4.6e-44	91.8
WP_001062586.1\|1459261_1459864_-	recombinase family protein	A0A219YA40	Aeromonas_phage	5.7e-17	38.3
WP_002779755.1\|1460250_1460424_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	4.6e-28	100.0
WP_000691759.1\|1460475_1462395_-	tetracycline resistance ribosomal protection protein Tet(O)	A0A1B0RXH7	Streptococcus_phage	0.0e+00	99.7
WP_001129923.1\|1462761_1463136_-	TnpV protein	D0R0F4	Streptococcus_phage	1.3e-67	99.2
WP_000893083.1\|1463940_1464231_-	hypothetical protein	NA	NA	NA	NA
WP_000169469.1\|1464244_1464544_-	hypothetical protein	NA	NA	NA	NA
WP_001236683.1\|1464614_1465958_-	DEAD/DEAH box helicase	H2DE57	Erwinia_phage	8.2e-56	31.6
WP_001258309.1\|1466095_1467874_-	hypothetical protein	A0A0U4J920	Pseudomonas_phage	8.9e-26	28.6

DBSCAN-SWA_6

1490191 : 1542898

Streptococcus_phage(54.17%)

integrase,protease,tRNA,transposase

attL 1503096:1503113|attR 1551058:1551075

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000619439.1\|1490191_1490776_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001005710.1\|1490778_1491012_-	hypothetical protein	NA	NA	NA	NA
WP_112409710.1\|1491020_1491404_-	hypothetical protein	NA	NA	NA	NA
WP_001050385.1\|1491414_1491843_-	hypothetical protein	NA	NA	NA	NA
WP_047210954.1\|1491826_1493182_-	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	3.1e-127	55.9
WP_000822780.1\|1493330_1494149_-	replication initiator protein A	A0A286QNA4	Streptococcus_phage	3.7e-11	35.5
WP_000902656.1\|1494529_1495891_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	7.4e-190	72.9
WP_001127193.1\|1497420_1497933_-	shikimate kinase	NA	NA	NA	NA
WP_000772014.1\|1497925_1499209_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000823931.1\|1499437_1500502_+	endonuclease	NA	NA	NA	NA
WP_000022832.1\|1500609_1501917_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.5e-235	95.4
WP_000137373.1\|1502114_1502570_+	YueI family protein	W6LLD2	Streptococcus_phage	7.8e-27	48.9
WP_000409124.1\|1502582_1503068_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_000589685.1\|1503088_1503730_-	phosphoserine phosphatase SerB	NA	NA	NA	NA
1503096:1503113	attL	NA	NA	NA	NA
WP_000094341.1\|1503823_1505548_-	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_000134196.1\|1505641_1507594_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.5e-143	44.8
WP_001106189.1\|1507594_1508155_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_000078931.1\|1508273_1509479_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_000027835.1\|1509903_1510092_-	hypothetical protein	J7KIW4	Streptococcus_phage	3.3e-16	78.2
WP_000076708.1\|1510133_1510334_-	CsbD family protein	J7KJ36	Streptococcus_phage	8.4e-26	97.0
WP_000734167.1\|1511210_1512530_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	8.4e-05	25.5
WP_000699093.1\|1512526_1513180_-	response regulator transcription factor	W8CYM9	Bacillus_phage	8.1e-25	33.6
WP_000594351.1\|1513276_1514653_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_000353149.1\|1514652_1515309_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-22	31.8
WP_000594360.1\|1515318_1516596_-	ABC transporter permease	NA	NA	NA	NA
WP_000508795.1\|1517337_1517499_+	TM2 domain-containing protein	NA	NA	NA	NA
WP_001867107.1\|1517671_1517881_-\|transposase	transposase	A0A0C5AEA5	Paenibacillus_phage	1.4e-15	55.4
WP_001865698.1\|1518006_1518267_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.4e-11	43.0
WP_001122304.1\|1518288_1518489_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_000640620.1\|1518650_1519055_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001872365.1\|1519054_1519321_+	hypothetical protein	Q77YW7	Streptococcus_phage	9.2e-20	65.2
WP_071659971.1\|1519323_1519938_+\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001068667.1\|1520082_1520430_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000595706.1\|1521013_1522210_-	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	3.6e-103	54.5
WP_000418127.1\|1522202_1522478_-	chorismate mutase	NA	NA	NA	NA
WP_001162136.1\|1522554_1522998_-	flavodoxin	NA	NA	NA	NA
WP_000189636.1\|1523056_1524079_-	adenosine deaminase	NA	NA	NA	NA
WP_000583233.1\|1524345_1525281_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_000710757.1\|1525389_1525650_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_001227397.1\|1525762_1527283_-	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_000752455.1\|1527424_1528822_-	C69 family dipeptidase	NA	NA	NA	NA
WP_000011316.1\|1528836_1529748_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.4e-107	65.7
WP_001231102.1\|1529744_1530719_-	YvcK family protein	A1IMD5	Streptococcus_phage	9.8e-144	78.8
WP_001278845.1\|1530715_1531606_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	7.4e-05	28.1
WP_000965178.1\|1531759_1532173_+	hypothetical protein	NA	NA	NA	NA
WP_001031103.1\|1532418_1533402_+	hypothetical protein	NA	NA	NA	NA
WP_000167485.1\|1533398_1533956_+	ECF transporter S component	NA	NA	NA	NA
WP_000038473.1\|1533995_1535342_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	3.7e-56	31.2
WP_000221828.1\|1535362_1536556_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000458617.1\|1536641_1539149_-	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	1.4e-218	50.5
WP_000048142.1\|1539256_1540021_-	(S)-acetoin forming diacetyl reductase	V5L4T3	Hirudovirus	9.8e-06	31.8
WP_001115859.1\|1540188_1540887_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.5e-82	64.9
WP_001022577.1\|1540883_1541594_+	thioesterase	NA	NA	NA	NA
WP_105253180.1\|1541663_1542898_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.8e-65	50.4
1551058:1551075	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2033643 : 2045707

Streptomyces_phage(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000783413.1\|2033643_2034948_-	LysM peptidoglycan-binding domain-containing protein	A0A2D1GNZ3	Streptomyces_phage	1.7e-05	40.5
WP_001045908.1\|2035094_2035994_-	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000166553.1\|2036186_2037734_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-77	48.9
WP_000780023.1\|2037753_2038506_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000685108.1\|2038528_2039077_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-25	35.6
WP_001291333.1\|2039243_2040266_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.0e-62	42.7
WP_000220675.1\|2040293_2041748_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_001042246.1\|2041981_2045707_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	4.3e-38	26.0

DBSCAN-SWA_8

2121230 : 2137401

Streptococcus_phage(71.43%)

integrase

attL 2123809:2123828|attR 2138216:2138235

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000230635.1\|2121230_2122586_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.2e-152	62.6
WP_001278152.1\|2122597_2122885_+	hypothetical protein	NA	NA	NA	NA
WP_000092759.1\|2123214_2123826_+	30S ribosomal protein S4	NA	NA	NA	NA
2123809:2123828	attL	NA	NA	NA	NA
WP_000605383.1\|2123932_2125105_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	5.7e-154	70.1
WP_000429449.1\|2125436_2126402_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	7.1e-86	51.1
WP_000350953.1\|2126428_2126770_-	hypothetical protein	A0A1S5SDB5	Streptococcus_phage	2.2e-13	59.7
WP_000946250.1\|2127480_2127768_-	DUF3102 domain-containing protein	A0A286QMZ8	Streptococcus_phage	1.9e-10	61.4
WP_001080841.1\|2127779_2128394_-	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	2.6e-17	68.7
WP_000359663.1\|2128599_2128800_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001258617.1\|2128823_2129444_+	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	2.2e-40	43.8
WP_000648623.1\|2129470_2129713_+	hypothetical protein	NA	NA	NA	NA
WP_001021393.1\|2129935_2130574_+	Bro-N domain-containing protein	NA	NA	NA	NA
WP_000130289.1\|2130672_2130846_+	hypothetical protein	NA	NA	NA	NA
WP_001259477.1\|2130934_2131441_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	2.2e-06	34.4
WP_000877495.1\|2131529_2131862_+	hypothetical protein	NA	NA	NA	NA
WP_017645222.1\|2131861_2132053_+	hypothetical protein	NA	NA	NA	NA
WP_000206023.1\|2132064_2132427_+	hypothetical protein	NA	NA	NA	NA
WP_071659938.1\|2132423_2132765_+	hypothetical protein	NA	NA	NA	NA
WP_000492119.1\|2132757_2133030_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	2.5e-28	69.8
WP_001869738.1\|2133198_2134020_+	DnaD domain protein	R9QM95	Lactococcus_phage	1.2e-30	68.7
WP_001258770.1\|2134100_2134706_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.4e-39	47.3
WP_000661533.1\|2134790_2135279_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	7.3e-47	56.2
WP_000500996.1\|2135677_2136040_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_000038828.1\|2136014_2136401_+	ArpU family transcriptional regulator	A0A141E173	Streptococcus_phage	1.8e-08	32.8
WP_000381996.1\|2136894_2137401_+	DUF4065 domain-containing protein	D7RWK7	Brochothrix_phage	3.0e-35	48.8
2138216:2138235	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP021773

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection