CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP031099	Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence	0 crisprs	NA	0	0	0
NZ_CP031100	Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence	0 crisprs	NA	0	0	2
NZ_CP031098	Clostridium botulinum strain CFSAN034202 chromosome, complete genome	4 crisprs	RT,DEDDh,cas3,WYL,csa3,DinG	1	8	5

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6140 : 24892

Pseudomonas_phage(16.67%)

portal,capsid,head,terminase,tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003385000.1\|6140_6746_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_003385001.1\|6792_6990_-	hypothetical protein	NA	NA	NA	NA
WP_003385002.1\|6998_7325_-	hypothetical protein	NA	NA	NA	NA
WP_050497295.1\|7338_8436_-\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	2.4e-66	35.4
WP_050497296.1\|8435_9365_-	hypothetical protein	A0A2D1GNL2	Pseudomonas_phage	4.1e-14	37.6
WP_003385006.1\|9510_9756_-	hypothetical protein	NA	NA	NA	NA
WP_154231186.1\|9759_9930_-	hypothetical protein	NA	NA	NA	NA
WP_080283532.1\|9971_10361_-	single-stranded DNA-binding protein	A0A0K0MWE1	Streptococcus_phage	1.3e-27	48.9
WP_154231177.1\|10357_10504_-	hypothetical protein	NA	NA	NA	NA
WP_154231176.1\|10569_10743_-	hypothetical protein	NA	NA	NA	NA
WP_154231175.1\|10770_10926_-	hypothetical protein	NA	NA	NA	NA
WP_031367494.1\|10903_11122_-	hypothetical protein	NA	NA	NA	NA
WP_031367559.1\|11124_12093_-	hypothetical protein	NA	NA	NA	NA
WP_031367560.1\|12092_12356_-	DUF1599 domain-containing protein	A0A2H4J4N1	uncultured_Caudovirales_phage	1.0e-31	79.1
WP_031367561.1\|12658_12865_-	hypothetical protein	NA	NA	NA	NA
WP_154231184.1\|13019_13175_-	hypothetical protein	NA	NA	NA	NA
WP_134791037.1\|13193_13445_-	hypothetical protein	NA	NA	NA	NA
WP_003385017.1\|13484_13835_-	hypothetical protein	NA	NA	NA	NA
WP_003385019.1\|13866_14049_-	hypothetical protein	NA	NA	NA	NA
WP_031367563.1\|14090_14750_-	DNA modification methylase	A0A1S5S9L2	Streptococcus_phage	8.0e-89	67.6
WP_003385021.1\|14791_15220_-	phage N-6-adenine-methyltransferase	A0A0A7RUD1	Clostridium_phage	3.5e-69	87.1
WP_031367565.1\|15266_15506_-	hypothetical protein	NA	NA	NA	NA
WP_003385025.1\|15666_16434_-\|capsid	minor capsid protein	W8VT12	Pseudomonas_phage	1.4e-07	33.9
WP_003385027.1\|16475_17789_-\|portal	phage portal protein	A0A0F7L7L5	uncultured_marine_virus	1.1e-23	23.0
WP_154231185.1\|17799_17973_-	hypothetical protein	NA	NA	NA	NA
WP_003385029.1\|18075_18474_-	hypothetical protein	NA	NA	NA	NA
WP_031367509.1\|18707_18962_-	hypothetical protein	NA	NA	NA	NA
WP_031367787.1\|19057_19441_-	hypothetical protein	NA	NA	NA	NA
WP_031367551.1\|19455_19698_-	hypothetical protein	NA	NA	NA	NA
WP_050497297.1\|19825_20530_-	helix-turn-helix domain-containing protein	F0PIG9	Enterococcus_phage	9.3e-19	46.8
WP_031367549.1\|20549_20813_-	hypothetical protein	NA	NA	NA	NA
WP_154231181.1\|20813_20972_-	hypothetical protein	NA	NA	NA	NA
WP_031367548.1\|21301_21493_-	DUF4236 domain-containing protein	A0A2K9V2W7	Faecalibacterium_phage	4.1e-14	58.7
WP_154231180.1\|21515_21692_-	hypothetical protein	NA	NA	NA	NA
WP_031367547.1\|21694_22111_-	hypothetical protein	NA	NA	NA	NA
WP_031367546.1\|23234_24479_-\|terminase	PBSX family phage terminase large subunit	A0A0S0KEN9	Bacillus_phage	7.6e-149	61.7
WP_003384520.1\|24481_24892_-\|terminase	terminase small subunit	A0A0A8WDX8	Clostridium_phage	4.0e-22	42.8

DBSCAN-SWA_2

32794 : 49096

Clostridium_phage(53.85%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031367568.1\|32794_32977_-	hypothetical protein	A0A0A7RTH9	Clostridium_phage	6.5e-17	82.5
WP_003384948.1\|33500_34130_-	FAD-dependent thymidylate synthase	F8UBK4	Clostridium_phage	2.0e-44	47.1
WP_154231187.1\|34198_34372_-	hypothetical protein	NA	NA	NA	NA
WP_003384949.1\|34424_34892_-	hypothetical protein	D9ZNH9	Clostridium_phage	9.2e-15	39.5
WP_003384950.1\|34948_35839_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_031367570.1\|35859_36369_-	hypothetical protein	S6AVW3	Thermus_phage	8.2e-25	39.9
WP_003384953.1\|36369_36579_-	hypothetical protein	NA	NA	NA	NA
WP_003384954.1\|36581_37136_-	hypothetical protein	Q332D2	Clostridium_botulinum_C_phage	4.3e-43	50.5
WP_003384956.1\|37150_37384_-	hypothetical protein	NA	NA	NA	NA
WP_154231188.1\|37386_37530_-	hypothetical protein	NA	NA	NA	NA
WP_003384958.1\|37567_37834_-	hypothetical protein	NA	NA	NA	NA
WP_031367571.1\|37827_39684_-	AAA family ATPase	K4NWL6	Pseudomonas_phage	6.3e-14	24.2
WP_050501308.1\|39696_40452_-	hypothetical protein	NA	NA	NA	NA
WP_031367515.1\|40475_40721_-	stage III sporulation protein D	M9Q261	Clostridium_phage	6.3e-15	52.0
WP_031367557.1\|40720_41038_-	hypothetical protein	NA	NA	NA	NA
WP_050497291.1\|41336_41948_-	hypothetical protein	A0A0A7RVW0	Clostridium_phage	2.7e-62	62.3
WP_031367555.1\|41963_42851_-	hypothetical protein	A0A088FAU5	Sulfitobacter_phage	1.9e-69	47.3
WP_031367554.1\|42869_43355_-	siphovirus Gp157 family protein	A0A059T5F1	Listeria_phage	1.2e-20	39.6
WP_003384967.1\|43822_44206_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_154231183.1\|44223_44364_+	hypothetical protein	NA	NA	NA	NA
WP_050497246.1\|44480_45530_-	hypothetical protein	A0A2H4JAA4	uncultured_Caudovirales_phage	3.3e-20	43.2
WP_003384969.1\|45933_46500_+	hypothetical protein	NA	NA	NA	NA
WP_003384970.1\|46617_47529_+	ParM/StbA family protein	NA	NA	NA	NA
WP_003384971.1\|47512_47800_+	hypothetical protein	NA	NA	NA	NA
WP_003384972.1\|47877_48294_-	hypothetical protein	I2E8W8	Clostridium_phage	8.2e-07	27.7
WP_033051712.1\|48304_49096_-	N-acetylmuramoyl-L-alanine amidase	I1TJX3	Clostridium_phage	5.5e-68	52.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP031098

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP031098_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031098_1

450771-451062

Orphan

III-B

Consensus_repeat	Method
GTTGAACAATAACATGAGATGTATTTAAAT	PILER-CR
GTTGAACAATAACATGAGATGTATTTAAAT	CRISPRCasFinder
GTTGAACAATAACATGAGATGTATTTAAAT	CRT

4 spacers

The CRISPR arrays of NZ_CP031098_1

>merge|NZ_CP031098|1|450771-451062|PILER-CR,CRISPRCasFinder,CRT
GTTGAACAATAACATGAGATGTATTTAAATTCCTCCATATCTCACATATCCTTTCTAAAACATTTCGTTGAACAATAACATGAGATGTATTTAAATGTTCTGATTTCAAATTTATTTACTATCCTTTCTAGTTGAACAATAACATGAGATGTATTTAAATAAAGTAAGTTTACTCTAGGTTGTCGAACTGTTCCCAGTTGAACAATAACATGAGATGTATTTAAATTACATTTTCATAAATCCAGTTGCCACTTTATTAACAGTTGAATAATAACATGAGATGTATTTAAAT

>NZ_CP031098|1|1|450771-451062|PILER-CR
GTTGAACAATAACATGAGATGTATTTAAAT	TCCTCCATATCTCACATATCCTTTCTAAAACATTTC
GTTGAACAATAACATGAGATGTATTTAAAT	GTTCTGATTTCAAATTTATTTACTATCCTTTCTA
GTTGAACAATAACATGAGATGTATTTAAAT	AAAGTAAGTTTACTCTAGGTTGTCGAACTGTTCCCA
GTTGAACAATAACATGAGATGTATTTAAAT	TACATTTTCATAAATCCAGTTGCCACTTTATTAACA
GTTGAATAATAACATGAGATGTATTTAAAT

>NZ_CP031098|1|1|450771-451062|CRISPRCasFinder
GTTGAACAATAACATGAGATGTATTTAAAT	TCCTCCATATCTCACATATCCTTTCTAAAACATTTC
GTTGAACAATAACATGAGATGTATTTAAAT	GTTCTGATTTCAAATTTATTTACTATCCTTTCTA
GTTGAACAATAACATGAGATGTATTTAAAT	AAAGTAAGTTTACTCTAGGTTGTCGAACTGTTCCCA
GTTGAACAATAACATGAGATGTATTTAAAT	TACATTTTCATAAATCCAGTTGCCACTTTATTAACA
GTTGAATAATAACATGAGATGTATTTAAAT

>NZ_CP031098|1|1|450771-451062|CRT
GTTGAACAATAACATGAGATGTATTTAAAT	TCCTCCATATCTCACATATCCTTTCTAAAACATTTC
GTTGAACAATAACATGAGATGTATTTAAAT	GTTCTGATTTCAAATTTATTTACTATCCTTTCTA
GTTGAACAATAACATGAGATGTATTTAAAT	AAAGTAAGTTTACTCTAGGTTGTCGAACTGTTCCCA
GTTGAACAATAACATGAGATGTATTTAAAT	TACATTTTCATAAATCCAGTTGCCACTTTATTAACA
GTTGAATAATAACATGAGATGTATTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031098.1\|WP_003358347.1\|449455_449902_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP031098.1\|WP_003358292.1\|462230_463121_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP031098.1\|WP_003358253.1\|458401_459199_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP031098.1\|WP_003358232.1\|441621_443046_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226458
NZ_CP031098.1\|WP_003358380.1\|439467_440253_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP031098.1\|WP_003358163.1\|440271_441321_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP031098.1\|WP_003358416.1\|448256_449288_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP031098.1\|WP_003358227.1\|456667_457588_+\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP031098.1\|WP_003358486.1\|443183_443957_+\|2-hydroxyglutaryl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|224835
NZ_CP031098.1\|WP_003358280.1\|445261_446584_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP031098.1\|WP_003358204.1\|461414_461936_-\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
NZ_CP031098.1\|WP_003358341.1\|463971_465378_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NZ_CP031098.1\|WP_003358401.1\|463127_463868_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP031098.1\|WP_003358167.1\|446924_447824_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358450.1\|454849_456343_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP031098.1\|WP_003358441.1\|449983_450436_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378897
NZ_CP031098.1\|WP_003358390.1\|451168_451552_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP031098.1\|WP_003358500.1\|459306_461304_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239241
NZ_CP031098.1\|WP_003358426.1\|451586_453050_-\|lipase	unknown	unknown	gnl\|CDD\|335313
NZ_CP031098.1\|WP_003358424.1\|444459_445194_+\|protein-kinase-family-protein	unknown	unknown	gnl\|CDD\|270622

Protein	Function_ID	Function_description	E-value
NZ_CP031098.1\|WP_003358347.1\|449455_449902_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.36279e-14
NZ_CP031098.1\|WP_003358292.1\|462230_463121_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.65473e-27
NZ_CP031098.1\|WP_003358253.1\|458401_459199_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.65908e-15
NZ_CP031098.1\|WP_003358232.1\|441621_443046_+\|hypothetical-protein	gnl\|CDD\|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	1.93876e-31
NZ_CP031098.1\|WP_003358380.1\|439467_440253_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	4.95122e-97
NZ_CP031098.1\|WP_003358163.1\|440271_441321_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	2.34921e-134
NZ_CP031098.1\|WP_003358416.1\|448256_449288_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.31432e-89
NZ_CP031098.1\|WP_003358227.1\|456667_457588_+\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	5.4972e-89
NZ_CP031098.1\|WP_003358486.1\|443183_443957_+\|2-hydroxyglutaryl-CoA-dehydratase	gnl\|CDD\|224835	COG1924, COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism].	2.63017e-97
NZ_CP031098.1\|WP_003358280.1\|445261_446584_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.674e-27
NZ_CP031098.1\|WP_003358204.1\|461414_461936_-\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	8.69116e-27
NZ_CP031098.1\|WP_003358341.1\|463971_465378_-\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.14712e-120
NZ_CP031098.1\|WP_003358401.1\|463127_463868_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0894e-12
NZ_CP031098.1\|WP_003358450.1\|454849_456343_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	4.01749e-120
NZ_CP031098.1\|WP_003358441.1\|449983_450436_-\|hypothetical-protein	gnl\|CDD\|378897	pfam12638, Staygreen, Staygreen protein. This family of proteins have been implicated in chlorophyll degradation. Intriguingly members of this family are also found in non-photosynthetic bacteria.	4.18402e-85
NZ_CP031098.1\|WP_003358390.1\|451168_451552_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.00619e-33
NZ_CP031098.1\|WP_003358500.1\|459306_461304_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
NZ_CP031098.1\|WP_003358426.1\|451586_453050_-\|lipase	gnl\|CDD\|335313	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II. Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipases A2, responsible for inactivation of platelet-activating factor through cleavage of an acetyl group. Three known PAF-AHs are the brain heterotrimeric PAF-AH Ib, whose catalytic beta and gamma subunits are aligned in pfam02266, the extracellular, plasma PAF-AH (pPAF-AH), and the intracellular PAF-AH isoform II (PAF-AH II). This family aligns pPAF-AH and PAF-AH II, whose similarity was previously noted.	5.31836e-18
NZ_CP031098.1\|WP_003358424.1\|444459_445194_+\|protein-kinase-family-protein	gnl\|CDD\|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	1.92812e-24

>NZ_CP031098.1|WP_003358441.1|449983_450436_-|hypothetical-protein
MSKLNPEKLSVEFRDGVTNTEPILGRRYTLTHSDITAELFLTIGLTYAYDKIDAMRDEVLGEWIEKEKNYLFHVYLHVDGNNPIVTGVRNHIFRRELPLALEAIRYGDRKFFISHPKLDNSSVIVHFISSYPSFNRIEKWGTFSDYSLKK
>NZ_CP031098.1|WP_003358347.1|449455_449902_+|helix-turn-helix-transcriptional-regulator
MSLGEKLLYLRKKASLSQEDVAEKLSVSRQTVSKWETDQTVPELNKAKLLSELYNVSYDYLISENYISGDVTGIEMIVDEIDWTGAWSKKYPILASYPGIKGINTYSEKISEIYDSFKNEFGFNDTDTVLVLKDILYQKYKMEKKKNK
>NZ_CP031098.1|WP_003358416.1|448256_449288_+|alpha/beta-hydrolase
MKKVIKVVSVILVILVIAGFFIIKNLTETKDGKLNMYVAANLQLYKILNPKSLNSKSIEETRGALNKQSTRWSNKPIPFSNIKNLHIKMNNEKIPVRIYTPEKGSNFPIIIYSHGGFWIGGNVDTIDGVCRKLSQNTKAILISVNYRLAPENPFPAGLNDVYNVLQWTYKNGKSINGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNISELNSKSWSYFSNSFNVSTEDMEKYISIYAPKKEDRKNPYASPLLSKDLRKLPDTLVVTAEIDPLRDEGEAYANKLKESGVKAEVTRYKGITHGFITMDKITNKADEALNQISLYIQKEFQK
>NZ_CP031098.1|WP_003358167.1|446924_447824_-|hypothetical-protein
MSNKRNLQSLRSFYICILIFNMVSNSIFHLNNNGFNIELFKNFTIRSVILLDLNILLFLIIVIAFEKKINIDEEVNTQLNTRIRPLYLVNIFFIAYILVCIFLLKDIDVILSSFIMEIIYIGIIILSKKIITLELTNRQLQWQKACGYIDEDCEESSFLWRFKLWWSPHVNVPFKNRWKGPSRLLYDLALVYGIIISKGNLFSLILLILLLPDVISWLEGLLGLQTSLTGICTGITEHHSKNSHVLYHKVYVTDYKNKREITFYVDGPLFIHENSHMTVVHGTFSKRVLYVEGLNLDIR
>NZ_CP031098.1|WP_003358280.1|445261_446584_-|APC-family-permease
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMIIAILGIFQGLNNGILIENFSKVSIISDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVIIYILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTIFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPEAFSKLNSKTNIPTNSTIANFILICIYLVVWYMNFKGLFPNKLFIDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKTSVIIDLGISVFVFLSGLLFYNKKK
>NZ_CP031098.1|WP_003358424.1|444459_445194_+|protein-kinase-family-protein
MVIKFFKRDTKYLPEQKIHEYTVLKVLGEGRFGICYLVQSNNKQYILKQLKTKMLKKIGSKVIYEQEILKNINHNCIPKFVKTLQFEKFFGYVLEYKEGKTFEEIICEDEYVFKREEIYDICIQIIEILKYLHKSGIVHRDIRIPNTIYYKKKVNLVDFGLARWINNKRYTENVDFSYLGDFLLHLYYTSFQCKTFKGKPWYEELDLFSEEMNFLKRLLGIEKKYKNIEEVERDFLLLKSNYNK
>NZ_CP031098.1|WP_003358486.1|443183_443957_+|2-hydroxyglutaryl-CoA-dehydratase
MYTMGLDIGSTTSKGVIIKDGKEIVASVLVPVGTGTSGPLKLIKELKEKSNLTEKDIEKTVVTGYGRIQYKDADKQISELSCHAKGVAFLIPGARTIIDIGGQDAKAMKLNDKGKLINFIMNDKCAAGTGRFLDVMAGVLETDVSKLGEISEKSTKEVSISSTCTVFAESEVISHLSANAKKEDIVAGIHTSVVRRVSTLAMRVGIEDQVVMVGGVARNKGIVKAMEKELGHDIKVPELAQLTGALGAAIYAFEETK
>NZ_CP031098.1|WP_003358232.1|441621_443046_+|hypothetical-protein
MSENSKSKVGFLTAFQVAAVWFGAHVGGGFATGNQTMNFFVKYGWHSIWLPAVIIIIIGLTYRESLVLAKNYGTYDYKSWSKKMYEPYDKFFSVIFEIGYLMIVLLGTGGSIAGSASLMETYGVNYLVGVLITGGIFYILTIYGSELIRKASTIITVLILIFLTIIVIVGIVNNSGNLSHLVSTKYSPSSFGTVLYSGLRYAGYQAFVVAIVLSASDTLKSDKAINKSILLGIILNGVMIILSCIMLLAWMPGAQKETIPILYICKRLNSGFLLFSYSVVLFLAFVSTGIGCVFGAVARFEHVFKKPENIKKRRGLISFVCMVLSMAISLFGLTKIVVIGYGYVGIIGIFAVVIPCIVVGRIKNNKFKKEQKENHITKEDQDNISKKDKDSILEGQDDISKEDKDSATEEDKDNVLKEEGSELKEYQDDISKKDEENGPVEGQDDASKGNKKSVPVEGQDDMPKEDKESASIEE
>NZ_CP031098.1|WP_003358163.1|440271_441321_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLADELIKFGADKVYYANDPLLEKYTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASNLDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPDNRPQMSTVRPGVMDKAVKDESRKGEILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQLADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDIIIAINKNESAPIFEVADYGIVGDLYDVVPKLLELLDDDHRINRLFEESKIV
>NZ_CP031098.1|WP_003358380.1|439467_440253_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MRIVVCVKQVPDTTEVKIDPKTGTLIREGVPSILNPDDANALEEALKMKDKDENVTVSVVSMGPPQADVMLRECLAMGADEAYLVSDRAFAGSDTWATSKVIASAIRKIGNYDIIFAGRQAIDGDTAQVGPQISEKLGIPQVTYVQDFKMEEDKITVQRQLEDGYEIIRVKKPALLTAVSSLNEPRYMAVDKIFDAYKKEIKVLTIDDLDIEKEGVGLKASPTKVFRSFTPAPKGKGVMLEGSTEEMAEKLVVSLKQKHII
>NZ_CP031098.1|WP_003358390.1|451168_451552_-|MerR-family-transcriptional-regulator
MNKMTRGELARQTGISTSTIRYYEDSGILPAPKRIANGYRIYTDDYLVKIKFIKDAKSLGYSLKEIKEILKMLSQEMDGENLKGLVKNKICEIEERIKTLHSIQRMLTDLLNTSEEDIQNYLQSFRI
>NZ_CP031098.1|WP_003358426.1|451586_453050_-|lipase
MRMLEVILFLVILAATGGILFVKPNRRLDIVFLMSVVLVMLLHGTINHFRIQMVPSYAVALMLIMVLIHRLIKSNSKPKSQSIPKSLFKKSFISILVLIFICTSAYLSFLLPVFTMPKPAGNYGIGTVSAHLTDESRAETLSTSPDDKREIMVNVWYPVDQKDIKGKTVEHYPSELGEAISLVFNIPKQLFTHLSQVSTHVVQGAKISTAESKYPVLLFSPGVRSTRFQSLTTIEELVSHGYIVVGLDHPYTSAKITFPDGRSIFYKPDTKSMTASELYKHNIGNVGFRVADVRFLLDTLTKWNKKDPNALLQGKLDLERIGMFGHSYGGATTAEALSQDNRLKAGVSLEGGFWGSVSQKGLKQPFMYLMSGGTAASFDPSTIKKDKVFYEEFIPDLQSVINKSTNNIYYLTVDHFIHQSFTDISLMSPLLFAKGIDPVHNIDITRSYVRAFFDQYLKGNHSILLDGPSSKYPEVKFSDIYTKKRLN
>NZ_CP031098.1|WP_003358450.1|454849_456343_-|PLP-dependent-aminotransferase-family-protein
MNIRIDKNSLITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLGLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRLKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NZ_CP031098.1|WP_003358227.1|456667_457588_+|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAIETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NZ_CP031098.1|WP_003358253.1|458401_459199_+|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIKVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKKAQYYMNLADAIGEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NZ_CP031098.1|WP_003358500.1|459306_461304_+|FAD-dependent-oxidoreductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGDSAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGEDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKMLIAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKNAVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEHIKKVLIVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLVDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNQVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>NZ_CP031098.1|WP_003358204.1|461414_461936_-|DUF4825-domain-containing-protein
MKNKFKVLVPLVLILSLNLIGCGINSEKKSKENIKNTSKVETYDLIKYKGTYVGDNSSVGNIIKNLPANEYSAGFSLQTSKEPYEITVNYKTNENLGEENYNKFWKDKKVEELLEKNAVILLSLIPNAEIIKFNVDNIGEESYKYNRKNLEQKYGSLEKQFTDNDSLNKFLNN
>NZ_CP031098.1|WP_003358292.1|462230_463121_+|AraC-family-transcriptional-regulator
MNYRKDIENCIEYIEEHIREPLTVNQITKEIGYSIYHFCRVFSFLKGMPLMEYVRRRKLSLSTIDLLEGQKIIDVALKWGFETPSSFARAFRKEFGCSPTQYIKKMKAYYKSKGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYTGENLESKLYKILSSLKHGEVGLCIPCSDSGDITYLLGVVVEDFSKVTSDMITVEVPKAQYAVFTTNPVNTVDSKDQREFAKIIKESWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>NZ_CP031098.1|WP_003358401.1|463127_463868_+|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPYAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFGIKLYDFGELEELILKAGFKGSYVFSDFKRRESVDKNSETFLYECYI
>NZ_CP031098.1|WP_003358341.1|463971_465378_-|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSVNTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKNGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK

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Crispr_ID: NZ_CP031098_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031098_2

453800-454354

Orphan

III-B

Consensus_repeat	Method
GTTAAACATTAACATGAGATGTATTTAAAT	PILER-CR
GTTAAACATTAACATGAGATGTATTTAAAT	CRISPRCasFinder
GTTAAACATTAACATGAGATGTATTTAAAT	CRT

8 spacers

The CRISPR arrays of NZ_CP031098_2

>merge|NZ_CP031098|2|453800-454354|PILER-CR,CRISPRCasFinder,CRT
GTTAAACATTAACATGAGATGTATTTAAATTTAAATCGATCAGTAATTAATATGTTTTTATCTCTTGTTAAACATTAACATGAGATGTATTTAAATCGTTTTTTTGTTGCAGGTTTTATTAAAAGTAATAGGTTAAACATTAACATGAGATGTATTTAAATAAGATAAGGCTTTCTGTACCCGTATTAAAATAAGTCGTTAAACATTAACATGAGATGTATTTAAATGAGGGAGATAAATATGACAGGAAGGTATGAAATAGTTAAACATTAACATGAGATGTATTTAAATATAATAAAAAGAAATAGTTATATATATATTGGACATGTTAAACATTGACATGAGATGTATTTAAATTTGTTTTTATAATCTGGTTCCCAATATTTAAAAGAAAGTTAAACATTAACATGAGATGTATTTAAATTTTCTAAAAGTTTTAGTATTAAACCTTTTTTCTTTTGTTGAACATTAACATGAGATGTATTTAAATTTATGATATGATTTTATTTGTTTAAGAGTATCTGCGTTGAACATTAACATGAGATGTATTTAAAT

>NZ_CP031098|2|2|453800-454354|PILER-CR
GTTAAACATTAACATGAGATGTATTTAAAT	TTAAATCGATCAGTAATTAATATGTTTTTATCTCTT
GTTAAACATTAACATGAGATGTATTTAAAT	CGTTTTTTTGTTGCAGGTTTTATTAAAAGTAATAG
GTTAAACATTAACATGAGATGTATTTAAAT	AAGATAAGGCTTTCTGTACCCGTATTAAAATAAGTC
GTTAAACATTAACATGAGATGTATTTAAAT	GAGGGAGATAAATATGACAGGAAGGTATGAAATA
GTTAAACATTAACATGAGATGTATTTAAAT	ATAATAAAAAGAAATAGTTATATATATATTGGACAT
GTTAAACATTGACATGAGATGTATTTAAAT	TTGTTTTTATAATCTGGTTCCCAATATTTAAAAGAAA
GTTAAACATTAACATGAGATGTATTTAAAT	TTTCTAAAAGTTTTAGTATTAAACCTTTTTTCTTTT
GTTGAACATTAACATGAGATGTATTTAAAT	TTATGATATGATTTTATTTGTTTAAGAGTATCTGC
GTTGAACATTAACATGAGATGTATTTAAAT

>NZ_CP031098|2|2|453800-454354|CRISPRCasFinder
GTTAAACATTAACATGAGATGTATTTAAAT	TTAAATCGATCAGTAATTAATATGTTTTTATCTCTT
GTTAAACATTAACATGAGATGTATTTAAAT	CGTTTTTTTGTTGCAGGTTTTATTAAAAGTAATAG
GTTAAACATTAACATGAGATGTATTTAAAT	AAGATAAGGCTTTCTGTACCCGTATTAAAATAAGTC
GTTAAACATTAACATGAGATGTATTTAAAT	GAGGGAGATAAATATGACAGGAAGGTATGAAATA
GTTAAACATTAACATGAGATGTATTTAAAT	ATAATAAAAAGAAATAGTTATATATATATTGGACAT
GTTAAACATTGACATGAGATGTATTTAAAT	TTGTTTTTATAATCTGGTTCCCAATATTTAAAAGAAA
GTTAAACATTAACATGAGATGTATTTAAAT	TTTCTAAAAGTTTTAGTATTAAACCTTTTTTCTTTT
GTTGAACATTAACATGAGATGTATTTAAAT	TTATGATATGATTTTATTTGTTTAAGAGTATCTGC
GTTGAACATTAACATGAGATGTATTTAAAT

>NZ_CP031098|2|2|453800-454354|CRT
GTTAAACATTAACATGAGATGTATTTAAAT	TTAAATCGATCAGTAATTAATATGTTTTTATCTCTT
GTTAAACATTAACATGAGATGTATTTAAAT	CGTTTTTTTGTTGCAGGTTTTATTAAAAGTAATAG
GTTAAACATTAACATGAGATGTATTTAAAT	AAGATAAGGCTTTCTGTACCCGTATTAAAATAAGTC
GTTAAACATTAACATGAGATGTATTTAAAT	GAGGGAGATAAATATGACAGGAAGGTATGAAATA
GTTAAACATTAACATGAGATGTATTTAAAT	ATAATAAAAAGAAATAGTTATATATATATTGGACAT
GTTAAACATTGACATGAGATGTATTTAAAT	TTGTTTTTATAATCTGGTTCCCAATATTTAAAAGAAA
GTTAAACATTAACATGAGATGTATTTAAAT	TTTCTAAAAGTTTTAGTATTAAACCTTTTTTCTTTT
GTTGAACATTAACATGAGATGTATTTAAAT	TTATGATATGATTTTATTTGTTTAAGAGTATCTGC
GTTGAACATTAACATGAGATGTATTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031098.1\|WP_003358347.1\|449455_449902_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP031098.1\|WP_003358292.1\|462230_463121_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP031098.1\|WP_003358253.1\|458401_459199_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP031098.1\|WP_003358232.1\|441621_443046_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226458
NZ_CP031098.1\|WP_154230954.1\|465738_465903_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358237.1\|466391_467006_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP031098.1\|WP_003358416.1\|448256_449288_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP031098.1\|WP_003358227.1\|456667_457588_+\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP031098.1\|WP_003358486.1\|443183_443957_+\|2-hydroxyglutaryl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|224835
NZ_CP031098.1\|WP_003358280.1\|445261_446584_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP031098.1\|WP_003358204.1\|461414_461936_-\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
NZ_CP031098.1\|WP_003358341.1\|463971_465378_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NZ_CP031098.1\|WP_003358401.1\|463127_463868_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP031098.1\|WP_003358167.1\|446924_447824_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358450.1\|454849_456343_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP031098.1\|WP_003358441.1\|449983_450436_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378897
NZ_CP031098.1\|WP_003358390.1\|451168_451552_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP031098.1\|WP_003358500.1\|459306_461304_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239241
NZ_CP031098.1\|WP_003358426.1\|451586_453050_-\|lipase	unknown	unknown	gnl\|CDD\|335313
NZ_CP031098.1\|WP_003358424.1\|444459_445194_+\|protein-kinase-family-protein	unknown	unknown	gnl\|CDD\|270622

Protein	Function_ID	Function_description	E-value
NZ_CP031098.1\|WP_003358347.1\|449455_449902_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.36279e-14
NZ_CP031098.1\|WP_003358292.1\|462230_463121_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.65473e-27
NZ_CP031098.1\|WP_003358253.1\|458401_459199_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.65908e-15
NZ_CP031098.1\|WP_003358232.1\|441621_443046_+\|hypothetical-protein	gnl\|CDD\|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	1.93876e-31
NZ_CP031098.1\|WP_003358237.1\|466391_467006_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.60101e-94
NZ_CP031098.1\|WP_003358416.1\|448256_449288_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.31432e-89
NZ_CP031098.1\|WP_003358227.1\|456667_457588_+\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	5.4972e-89
NZ_CP031098.1\|WP_003358486.1\|443183_443957_+\|2-hydroxyglutaryl-CoA-dehydratase	gnl\|CDD\|224835	COG1924, COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism].	2.63017e-97
NZ_CP031098.1\|WP_003358280.1\|445261_446584_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.674e-27
NZ_CP031098.1\|WP_003358204.1\|461414_461936_-\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	8.69116e-27
NZ_CP031098.1\|WP_003358341.1\|463971_465378_-\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.14712e-120
NZ_CP031098.1\|WP_003358401.1\|463127_463868_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0894e-12
NZ_CP031098.1\|WP_003358450.1\|454849_456343_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	4.01749e-120
NZ_CP031098.1\|WP_003358441.1\|449983_450436_-\|hypothetical-protein	gnl\|CDD\|378897	pfam12638, Staygreen, Staygreen protein. This family of proteins have been implicated in chlorophyll degradation. Intriguingly members of this family are also found in non-photosynthetic bacteria.	4.18402e-85
NZ_CP031098.1\|WP_003358390.1\|451168_451552_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.00619e-33
NZ_CP031098.1\|WP_003358500.1\|459306_461304_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
NZ_CP031098.1\|WP_003358426.1\|451586_453050_-\|lipase	gnl\|CDD\|335313	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II. Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipases A2, responsible for inactivation of platelet-activating factor through cleavage of an acetyl group. Three known PAF-AHs are the brain heterotrimeric PAF-AH Ib, whose catalytic beta and gamma subunits are aligned in pfam02266, the extracellular, plasma PAF-AH (pPAF-AH), and the intracellular PAF-AH isoform II (PAF-AH II). This family aligns pPAF-AH and PAF-AH II, whose similarity was previously noted.	5.31836e-18
NZ_CP031098.1\|WP_003358424.1\|444459_445194_+\|protein-kinase-family-protein	gnl\|CDD\|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	1.92812e-24

>NZ_CP031098.1|WP_003358426.1|451586_453050_-|lipase
MRMLEVILFLVILAATGGILFVKPNRRLDIVFLMSVVLVMLLHGTINHFRIQMVPSYAVALMLIMVLIHRLIKSNSKPKSQSIPKSLFKKSFISILVLIFICTSAYLSFLLPVFTMPKPAGNYGIGTVSAHLTDESRAETLSTSPDDKREIMVNVWYPVDQKDIKGKTVEHYPSELGEAISLVFNIPKQLFTHLSQVSTHVVQGAKISTAESKYPVLLFSPGVRSTRFQSLTTIEELVSHGYIVVGLDHPYTSAKITFPDGRSIFYKPDTKSMTASELYKHNIGNVGFRVADVRFLLDTLTKWNKKDPNALLQGKLDLERIGMFGHSYGGATTAEALSQDNRLKAGVSLEGGFWGSVSQKGLKQPFMYLMSGGTAASFDPSTIKKDKVFYEEFIPDLQSVINKSTNNIYYLTVDHFIHQSFTDISLMSPLLFAKGIDPVHNIDITRSYVRAFFDQYLKGNHSILLDGPSSKYPEVKFSDIYTKKRLN
>NZ_CP031098.1|WP_003358390.1|451168_451552_-|MerR-family-transcriptional-regulator
MNKMTRGELARQTGISTSTIRYYEDSGILPAPKRIANGYRIYTDDYLVKIKFIKDAKSLGYSLKEIKEILKMLSQEMDGENLKGLVKNKICEIEERIKTLHSIQRMLTDLLNTSEEDIQNYLQSFRI
>NZ_CP031098.1|WP_003358441.1|449983_450436_-|hypothetical-protein
MSKLNPEKLSVEFRDGVTNTEPILGRRYTLTHSDITAELFLTIGLTYAYDKIDAMRDEVLGEWIEKEKNYLFHVYLHVDGNNPIVTGVRNHIFRRELPLALEAIRYGDRKFFISHPKLDNSSVIVHFISSYPSFNRIEKWGTFSDYSLKK
>NZ_CP031098.1|WP_003358347.1|449455_449902_+|helix-turn-helix-transcriptional-regulator
MSLGEKLLYLRKKASLSQEDVAEKLSVSRQTVSKWETDQTVPELNKAKLLSELYNVSYDYLISENYISGDVTGIEMIVDEIDWTGAWSKKYPILASYPGIKGINTYSEKISEIYDSFKNEFGFNDTDTVLVLKDILYQKYKMEKKKNK
>NZ_CP031098.1|WP_003358416.1|448256_449288_+|alpha/beta-hydrolase
MKKVIKVVSVILVILVIAGFFIIKNLTETKDGKLNMYVAANLQLYKILNPKSLNSKSIEETRGALNKQSTRWSNKPIPFSNIKNLHIKMNNEKIPVRIYTPEKGSNFPIIIYSHGGFWIGGNVDTIDGVCRKLSQNTKAILISVNYRLAPENPFPAGLNDVYNVLQWTYKNGKSINGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPPITCQVLIYPSTNISELNSKSWSYFSNSFNVSTEDMEKYISIYAPKKEDRKNPYASPLLSKDLRKLPDTLVVTAEIDPLRDEGEAYANKLKESGVKAEVTRYKGITHGFITMDKITNKADEALNQISLYIQKEFQK
>NZ_CP031098.1|WP_003358167.1|446924_447824_-|hypothetical-protein
MSNKRNLQSLRSFYICILIFNMVSNSIFHLNNNGFNIELFKNFTIRSVILLDLNILLFLIIVIAFEKKINIDEEVNTQLNTRIRPLYLVNIFFIAYILVCIFLLKDIDVILSSFIMEIIYIGIIILSKKIITLELTNRQLQWQKACGYIDEDCEESSFLWRFKLWWSPHVNVPFKNRWKGPSRLLYDLALVYGIIISKGNLFSLILLILLLPDVISWLEGLLGLQTSLTGICTGITEHHSKNSHVLYHKVYVTDYKNKREITFYVDGPLFIHENSHMTVVHGTFSKRVLYVEGLNLDIR
>NZ_CP031098.1|WP_003358280.1|445261_446584_-|APC-family-permease
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMIIAILGIFQGLNNGILIENFSKVSIISDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVIIYILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTIFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPEAFSKLNSKTNIPTNSTIANFILICIYLVVWYMNFKGLFPNKLFIDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKTSVIIDLGISVFVFLSGLLFYNKKK
>NZ_CP031098.1|WP_003358424.1|444459_445194_+|protein-kinase-family-protein
MVIKFFKRDTKYLPEQKIHEYTVLKVLGEGRFGICYLVQSNNKQYILKQLKTKMLKKIGSKVIYEQEILKNINHNCIPKFVKTLQFEKFFGYVLEYKEGKTFEEIICEDEYVFKREEIYDICIQIIEILKYLHKSGIVHRDIRIPNTIYYKKKVNLVDFGLARWINNKRYTENVDFSYLGDFLLHLYYTSFQCKTFKGKPWYEELDLFSEEMNFLKRLLGIEKKYKNIEEVERDFLLLKSNYNK
>NZ_CP031098.1|WP_003358486.1|443183_443957_+|2-hydroxyglutaryl-CoA-dehydratase
MYTMGLDIGSTTSKGVIIKDGKEIVASVLVPVGTGTSGPLKLIKELKEKSNLTEKDIEKTVVTGYGRIQYKDADKQISELSCHAKGVAFLIPGARTIIDIGGQDAKAMKLNDKGKLINFIMNDKCAAGTGRFLDVMAGVLETDVSKLGEISEKSTKEVSISSTCTVFAESEVISHLSANAKKEDIVAGIHTSVVRRVSTLAMRVGIEDQVVMVGGVARNKGIVKAMEKELGHDIKVPELAQLTGALGAAIYAFEETK
>NZ_CP031098.1|WP_003358232.1|441621_443046_+|hypothetical-protein
MSENSKSKVGFLTAFQVAAVWFGAHVGGGFATGNQTMNFFVKYGWHSIWLPAVIIIIIGLTYRESLVLAKNYGTYDYKSWSKKMYEPYDKFFSVIFEIGYLMIVLLGTGGSIAGSASLMETYGVNYLVGVLITGGIFYILTIYGSELIRKASTIITVLILIFLTIIVIVGIVNNSGNLSHLVSTKYSPSSFGTVLYSGLRYAGYQAFVVAIVLSASDTLKSDKAINKSILLGIILNGVMIILSCIMLLAWMPGAQKETIPILYICKRLNSGFLLFSYSVVLFLAFVSTGIGCVFGAVARFEHVFKKPENIKKRRGLISFVCMVLSMAISLFGLTKIVVIGYGYVGIIGIFAVVIPCIVVGRIKNNKFKKEQKENHITKEDQDNISKKDKDSILEGQDDISKEDKDSATEEDKDNVLKEEGSELKEYQDDISKKDEENGPVEGQDDASKGNKKSVPVEGQDDMPKEDKESASIEE
>NZ_CP031098.1|WP_003358450.1|454849_456343_-|PLP-dependent-aminotransferase-family-protein
MNIRIDKNSLITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLGLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRLKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NZ_CP031098.1|WP_003358227.1|456667_457588_+|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAIETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NZ_CP031098.1|WP_003358253.1|458401_459199_+|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIKVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKKAQYYMNLADAIGEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NZ_CP031098.1|WP_003358500.1|459306_461304_+|FAD-dependent-oxidoreductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGDSAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGEDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKMLIAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKNAVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEHIKKVLIVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLVDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNQVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>NZ_CP031098.1|WP_003358204.1|461414_461936_-|DUF4825-domain-containing-protein
MKNKFKVLVPLVLILSLNLIGCGINSEKKSKENIKNTSKVETYDLIKYKGTYVGDNSSVGNIIKNLPANEYSAGFSLQTSKEPYEITVNYKTNENLGEENYNKFWKDKKVEELLEKNAVILLSLIPNAEIIKFNVDNIGEESYKYNRKNLEQKYGSLEKQFTDNDSLNKFLNN
>NZ_CP031098.1|WP_003358292.1|462230_463121_+|AraC-family-transcriptional-regulator
MNYRKDIENCIEYIEEHIREPLTVNQITKEIGYSIYHFCRVFSFLKGMPLMEYVRRRKLSLSTIDLLEGQKIIDVALKWGFETPSSFARAFRKEFGCSPTQYIKKMKAYYKSKGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYTGENLESKLYKILSSLKHGEVGLCIPCSDSGDITYLLGVVVEDFSKVTSDMITVEVPKAQYAVFTTNPVNTVDSKDQREFAKIIKESWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>NZ_CP031098.1|WP_003358401.1|463127_463868_+|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPYAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFGIKLYDFGELEELILKAGFKGSYVFSDFKRRESVDKNSETFLYECYI
>NZ_CP031098.1|WP_003358341.1|463971_465378_-|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSVNTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKNGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NZ_CP031098.1|WP_154230954.1|465738_465903_+|hypothetical-protein
MSKMHVTMVACSPNEEIGSKLGRINLPCSAGNASSLLEELIFVITSLSILLYNA
>NZ_CP031098.1|WP_003358237.1|466391_467006_+|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGIHMGNNVVIGSGSVVIKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDIDDYKG

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Crispr_ID: NZ_CP031098_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031098_3

467571-467794

Orphan

III-B

Consensus_repeat	Method
GTTGAACAGTAACATAAGATGTATTTAA	CRISPRCasFinder
GTTGAACAGTAACATAAGATGTATTTAAAT	CRT
ATGTTGAACAGTAACATAAGATGTATTTAAAT	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP031098_3

>merge|NZ_CP031098|3|467571-467794|CRISPRCasFinder,CRT,PILER-CR
GTTGAACATTAACATGAGATGTATTTAAATTTTGCTTCACACCAGGAACTTAGCCCCTCTATTGTTGTTAAACAGTAACATAAGATGTATTTAAATTCAAATAGAATTACATTTTCTATGATAAAATTATGTTGAACAGTAACATAAGATGTATTTAAATAAATATATTCATCTTCGATATTTGTTTCATCAACGTTGAACAGTAACATAAGATGTATTTAAGC

>NZ_CP031098|3|3|467571-467792|CRISPRCasFinder
GTTGAACATTAACATGAGATGTATTTAA	ATTTTGCTTCACACCAGGAACTTAGCCCCTCTATTGTT
GTTAAACAGTAACATAAGATGTATTTAA	ATTCAAATAGAATTACATTTTCTATGATAAAATTAT
GTTGAACAGTAACATAAGATGTATTTAA	ATAAATATATTCATCTTCGATATTTGTTTCATCAAC
GTTGAACAGTAACATAAGATGTATTTAA

>NZ_CP031098|3|3|467571-467794|CRT
GTTGAACATTAACATGAGATGTATTTAAAT	TTTGCTTCACACCAGGAACTTAGCCCCTCTATTGTT
GTTAAACAGTAACATAAGATGTATTTAAAT	TCAAATAGAATTACATTTTCTATGATAAAATTAT
GTTGAACAGTAACATAAGATGTATTTAAAT	AAATATATTCATCTTCGATATTTGTTTCATCAAC
GTTGAACAGTAACATAAGATGTATTTAAGC

>NZ_CP031098|3|3|467636-467794|PILER-CR
TGTTAAACAGTAACATAAGATGTATTTAAATT	CAAATAGAATTACATTTTCTATGATAAAATTA
TGTTGAACAGTAACATAAGATGTATTTAAATA	AATATATTCATCTTCGATATTTGTTTCATCAA
CGTTGAACAGTAACATAAGATGTATTTAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031098.1\|WP_003358292.1\|462230_463121_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP031098.1\|WP_003358253.1\|458401_459199_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP031098.1\|WP_003358485.1\|476473_478465_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP031098.1\|WP_154230954.1\|465738_465903_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358304.1\|469074_469791_+\|transaldolase	unknown	unknown	gnl\|CDD\|183481
NZ_CP031098.1\|WP_003358237.1\|466391_467006_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP031098.1\|WP_003358211.1\|470577_471942_+\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
NZ_CP031098.1\|WP_031367211.1\|468087_468822_+\|transpeptidase-transglycosylase	unknown	unknown	gnl\|CDD\|236545
NZ_CP031098.1\|WP_003358196.1\|479030_480170_+\|DOIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341476
NZ_CP031098.1\|WP_003358406.1\|475716_476484_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP031098.1\|WP_003358412.1\|469814_470252_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP031098.1\|WP_003358500.1\|459306_461304_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239241
NZ_CP031098.1\|WP_003358482.1\|470280_470565_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
NZ_CP031098.1\|WP_003358204.1\|461414_461936_-\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
NZ_CP031098.1\|WP_003358341.1\|463971_465378_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NZ_CP031098.1\|WP_003358401.1\|463127_463868_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP031098.1\|WP_003358205.1\|474575_474929_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
NZ_CP031098.1\|WP_003358483.1\|472153_474247_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP031098.1\|WP_003358227.1\|456667_457588_+\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP031098.1\|WP_003358491.1\|467122_467308_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP031098.1\|WP_003358292.1\|462230_463121_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.65473e-27
NZ_CP031098.1\|WP_003358253.1\|458401_459199_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.65908e-15
NZ_CP031098.1\|WP_003358485.1\|476473_478465_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.00109669
NZ_CP031098.1\|WP_003358205.1\|474575_474929_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000168002
NZ_CP031098.1\|WP_003358237.1\|466391_467006_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.60101e-94
NZ_CP031098.1\|WP_003358211.1\|470577_471942_+\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NZ_CP031098.1\|WP_031367211.1\|468087_468822_+\|transpeptidase-transglycosylase	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	6.0153e-12
NZ_CP031098.1\|WP_003358196.1\|479030_480170_+\|DOIS-domain-containing-protein	gnl\|CDD\|341476	cd08197, DOIS, 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose. 2-deoxy-scyllo-inosose synthase (DOIS) catalyzes carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose through a multistep reaction in the biosynthesis of aminoglycoside antibiotics. 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotics includes neomycin, kanamycin, gentamicin, and ribostamycin. They are important antibacterial agents. DOIS is a homolog of the dehydroquinate synthase which catalyzes the cyclization of 3-deoxy-D-arabino-heputulosonate-7-phosphate to dehydroquinate (DHQ) in the shikimate pathway.	2.49376e-155
NZ_CP031098.1\|WP_003358406.1\|475716_476484_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.94448e-103
NZ_CP031098.1\|WP_003358412.1\|469814_470252_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	8.56383e-38
NZ_CP031098.1\|WP_003358500.1\|459306_461304_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
NZ_CP031098.1\|WP_003358482.1\|470280_470565_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	1.57443e-28
NZ_CP031098.1\|WP_003358204.1\|461414_461936_-\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	8.69116e-27
NZ_CP031098.1\|WP_003358304.1\|469074_469791_+\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.39385e-155
NZ_CP031098.1\|WP_003358401.1\|463127_463868_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.0894e-12
NZ_CP031098.1\|WP_003358483.1\|472153_474247_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	7.70783e-57
NZ_CP031098.1\|WP_003358227.1\|456667_457588_+\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	5.4972e-89
NZ_CP031098.1\|WP_003358341.1\|463971_465378_-\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.14712e-120

>NZ_CP031098.1|WP_003358491.1|467122_467308_+|hypothetical-protein
MIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHVKGAGIGTIIGAIVALLSGGMVHFISII
>NZ_CP031098.1|WP_003358237.1|466391_467006_+|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGIHMGNNVVIGSGSVVIKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDIDDYKG
>NZ_CP031098.1|WP_154230954.1|465738_465903_+|hypothetical-protein
MSKMHVTMVACSPNEEIGSKLGRINLPCSAGNASSLLEELIFVITSLSILLYNA
>NZ_CP031098.1|WP_003358341.1|463971_465378_-|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSVNTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKNGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NZ_CP031098.1|WP_003358401.1|463127_463868_+|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPYAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGGNLLGKEEMDFGIKLYDFGELEELILKAGFKGSYVFSDFKRRESVDKNSETFLYECYI
>NZ_CP031098.1|WP_003358292.1|462230_463121_+|AraC-family-transcriptional-regulator
MNYRKDIENCIEYIEEHIREPLTVNQITKEIGYSIYHFCRVFSFLKGMPLMEYVRRRKLSLSTIDLLEGQKIIDVALKWGFETPSSFARAFRKEFGCSPTQYIKKMKAYYKSKGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYTGENLESKLYKILSSLKHGEVGLCIPCSDSGDITYLLGVVVEDFSKVTSDMITVEVPKAQYAVFTTNPVNTVDSKDQREFAKIIKESWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>NZ_CP031098.1|WP_003358204.1|461414_461936_-|DUF4825-domain-containing-protein
MKNKFKVLVPLVLILSLNLIGCGINSEKKSKENIKNTSKVETYDLIKYKGTYVGDNSSVGNIIKNLPANEYSAGFSLQTSKEPYEITVNYKTNENLGEENYNKFWKDKKVEELLEKNAVILLSLIPNAEIIKFNVDNIGEESYKYNRKNLEQKYGSLEKQFTDNDSLNKFLNN
>NZ_CP031098.1|WP_003358500.1|459306_461304_+|FAD-dependent-oxidoreductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNERGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGDSAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGEDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKMLIAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKNAVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEHIKKVLIVGGGVAGMEAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLVDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNQVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>NZ_CP031098.1|WP_003358253.1|458401_459199_+|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIKVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKKAQYYMNLADAIGEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NZ_CP031098.1|WP_003358227.1|456667_457588_+|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAIETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NZ_CP031098.1|WP_031367211.1|468087_468822_+|transpeptidase-transglycosylase
MDKFRNMKKSHVALLVVMYMVLMGSFPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKIKAENEQAQAAFAQSTGKGNSNDQSNGSENVDNNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEGLSPCSVCNP
>NZ_CP031098.1|WP_003358304.1|469074_469791_+|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVIGALKSGVDSIVSVFAGRIADTGEDSVKIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NZ_CP031098.1|WP_003358412.1|469814_470252_+|PTS-transporter-subunit-EIIA
MLKNYINDQVVEVNVEVENWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPETGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NZ_CP031098.1|WP_003358482.1|470280_470565_+|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEQLKK
>NZ_CP031098.1|WP_003358211.1|470577_471942_+|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NZ_CP031098.1|WP_003358483.1|472153_474247_+|BglG-family-transcription-antiterminator
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFATINMLSDRMMVSRSTIINDLIEVKKWLSENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYAIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDISDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRNNSEECNSSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLNIKDPTLTEDHKPSLKELLKPDFIKLNEEAEDWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFLSKVKNIKASSEIDSILYS
>NZ_CP031098.1|WP_003358205.1|474575_474929_+|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYANK
>NZ_CP031098.1|WP_003358406.1|475716_476484_+|ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDGKVESVAKYLEIEKVLEKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKATILMVTHDAFAASYAHRILFIKDGKIFNELIRGNDTRKEFFNKIIEVTSLLGGDDNNVF
>NZ_CP031098.1|WP_003358485.1|476473_478465_+|ABC-transporter-permease
MYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSRLMEFMSAISVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVRETSIVGAISLIAGLIIGIGVSQGLSVLTLKLFEVSINEYKFAVSTRAIGKTILYFGVMFLLVMIFNVFVISKYKIIDLLTSCRKNENMKFKNTFIYLLSFLLCVVLLGFAYKSILKTGLKLRDPMFKPSIAFVIIGTVLFFFSLAGVILYVVNKNKRIYFKGLNMFVVKQINSKVNTNFLSMSLICLMLFITILILSTGISLKNGVEEGAKIKAPFDASIIISNNSKKDNLEDVLDKINFKRSKNEKYATFNNYFSGIKLESLLPITDKDYKNAEVSFVKISDYNKMLKLKGKKEINLNKDEILIMSTNNNMVKQANEKLKNSKKFNIKGKEYLVKNNKIIDENLATYLLADNVFTVIISDEFLYDYNKIVYSILNVMYSDKNREENNKKYREINKNYLDGKYKSLNISYMGAFSKDDIYSHSKGGTTTVLFVGIYLGLVFLITSMAVLALQQLSEASDSIERYKALKRIGANSKMIDKTIFLQTFIYFAIPMILALIHSVIGIKVISDYIEVFTKIDISFSALITALIFILVYAGYFYTTYIGYKNIVESNI
>NZ_CP031098.1|WP_003358196.1|479030_480170_+|DOIS-domain-containing-protein
MYMNLAQKINDDYYHPEVKLETNLLESSPIYLGCNIWRESLLGKMMDLNTDKFFLITDDVVYNLFGKELLEYMNRKVSVKLIKLPSGEKHKNIKVFNDLMEDLFDNNVTKSSILISLGGGVVGNITGLAAALAFRGIRFFHIPTTFMSQTDSILSRKQGINSFYGKNMIGSYYTPLFNFIDTSFLTFDSERFIRGSFVETVKNGFIYDADFLNKLKSVIKNDFNVNQEGIFNLVKMSIESKLPIMKADPTEKGLAMILEYGHTIGHAIEKLSHGKLSHGESVSIGMMVAARISEKLGYLSKQDVKEHLDILSALKTPTKIPSNIKISDIINRIKLDNKKDMNGIRFVVLESIGKCINTDGSYMIKVPFNIINEAIEETC

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Crispr_ID: NZ_CP031098_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031098_4

3534040-3534110

Orphan

Consensus_repeat	Method
ACTAGTTTATTTTTTATTGAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP031098_4

>merge|NZ_CP031098|4|3534040-3534110|CRISPRCasFinder
ACTAGTTTATTTTTTATTGAAAAAAATATTACAACCAATATTGTTAGAACTAATTTATTTTTTATTGAAAA

>NZ_CP031098|4|4|3534040-3534110|CRISPRCasFinder
ACTAGTTTATTTTTTATTGAAAA	AAATATTACAACCAATATTGTTAGA
ACTAATTTATTTTTTATTGAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031098.1\|WP_003358009.1\|3541831_3542086_+\|membrane-protein	unknown	unknown	gnl\|CDD\|371241
NZ_CP031098.1\|WP_162265969.1\|3525385_3525628_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003357869.1\|3527628_3528714_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003357959.1\|3542104_3542299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358123.1\|3536274_3537360_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358000.1\|3529082_3530432_+\|caspase-family-protein	unknown	unknown	gnl\|CDD\|334197
NZ_CP031098.1\|WP_003357870.1\|3540866_3541676_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003357973.1\|3527207_3527642_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358083.1\|3534977_3535253_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003357715.1\|3525791_3527195_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227699
NZ_CP031098.1\|WP_003357799.1\|3531433_3532942_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358070.1\|3539976_3540801_+\|discoidin-domain-containing-protein	unknown	unknown	gnl\|CDD\|369494
NZ_CP031098.1\|WP_003357967.1\|3525009_3525426_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358129.1\|3530433_3531411_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358057.1\|3535264_3536263_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003393065.1\|3538312_3539092_+\|discoidin-domain-containing-protein	unknown	unknown	gnl\|CDD\|366285
NZ_CP031098.1\|WP_003357911.1\|3539143_3539911_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003357852.1\|3524107_3524995_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003358023.1\|3537392_3538310_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031098.1\|WP_003357831.1\|3528726_3529068_+\|hypothetical-protein	unknown	unknown	unknown

>NZ_CP031098.1|WP_003357799.1|3531433_3532942_+|hypothetical-protein
MATDNFYCVNGNTSVKDIIKNLTKEITQSAGIYKWDLVSPSAIDKVRNFSLIKATTSYGKEFYIRFERTAALTPTSEEQKLLDKERYSKPFTEQEITLLNRYVEAMPLTSFEKNLIKKNLDSLTTDEQNDLQQLRVRKNITNDRELFLLRKYYNGESLSTAEQNELDTYRNAHNLTAQELVDWSKLKTNTKLYADSIINILYKQYAGSVLSQSEQNSLASYRNSMELTQSEKEKLAMLKGKMDNRNHMYITIGKEIHDTKKIVEVDGEQTEVDIKDLVEESCSVPSRFAWYKKLAPEIGEWLPIEYYINITKDAVNIMLEGDKSADNYPYNNNLTSYAYIGAIKPMEDSASTDDKYNFGVVTSSDIPPFFTKKFGERTATGITDVCMVGNKIGMPMQPHYPEFSTTTTFVDKCNTEGSRWNHKKHKFDEIILFHPVDGERGKLINVLAGDGNGIWNKDTLVYKKGTEEEENYKKFKITAPYSLMNNSPNPLYCIAIRWYKSE
>NZ_CP031098.1|WP_003358129.1|3530433_3531411_+|hypothetical-protein
MSLPKYIINFEELTEDLKNHLLSLIDDNIRTNYPEINTNNIQDLLQQLKDLLPSVQYEGLKKKIDTFIYRKIEGIQKVKGILLDIPAIQNDYKEQIKFDKDIYITGLHFNQTGWKKDDRYSLEVNKMKIIDNATTKEIGEHKYFNTFYKVNANTPISFVFHNLSGNSRQIIVDLEYIDGEDSNIPVEPPGIEDIDNEWDIAVVMNWEENTDADIDLHGKIDDKKVWHGNRSYDGFYLNFDYTSHKTNKNPEIISVKGYKNRKLHISIRNFNGAELKEPVTLEIYKYRPYGNKLLKKFNVNLDTNRDLKEIFIMDLNTLKITNLNK
>NZ_CP031098.1|WP_003358000.1|3529082_3530432_+|caspase-family-protein
MGLPSYVVNFDELSDLIKDYLQNGVKVDIGNINFSTKDMENLLSEIKDKIQGVDYNDLINALNALGVKLDNLSGNLGISGTQKIYGKMLEIPAVKGQHIIEFKGNGQITGITYSQSSWRFEDSWDLQVGNDKLFESVRTKEYGEHKFLNVFYPINGTVKFIYNNISGTSKVLWVDFNILENSNLPTPTTPTIPTTNEKKYRFLAIGESEYTLQGANNLMGCTYDADNMSNLFKEHKQSAKFTKNIVAKNKTKSEALNLIKNTFQDAQDNDISYLFWSGHGTVYEDKFALVAKDNIITVYELQTILDDIKGTKVIFIDTCHSGLAIDKNFAYTLAVVEEKLRSIDKTLNKQGYKVLTASAGSETSGDLSAGYNGNPNPSGAFTWALTQSIKTKKSDKDKNRIVTLEELYQSVLHFYDEFNIKNPYLKITQTAQVYPRNDTSSIFEYKEGA
>NZ_CP031098.1|WP_003357831.1|3528726_3529068_+|hypothetical-protein
MAHMGYKNFREPVVYILDQELRKRNFKNQINTNEDSKYTGELPEYPCRIIRDSNNKAYKFIYASGTDMQWQEELIRNAEGKVYRIKTTYPNNTNKTIQLIKDNHGKLETIDYV
>NZ_CP031098.1|WP_003357869.1|3527628_3528714_+|hypothetical-protein
MTKCKVEFYKKNGYQAFENGDANKITLEHCLVSVKINRNLTTPTAEATITAQYENLPTAIFAGGTQGIIDNFAQVKIYIEDVLQFTGVIKKYDYNTLDKTIEMTCHDMYYRMLNLCDKELKFYNKTAADIISTVVSDAKCSFQRNGGNNYTVSKLECEIGTMYNDIIGNLVETMYARIRANKNGVIILEEQYPAYNESNHEANHHDYVLSVDTNLSSETASRDSSLMRNILKICCNDKYSIFESKAMTSYLNGERWVDIIDNPLASTSLLKQKVAGYKFLDMWRDSTALNVVPVTGIPNIDLGQVVKLVNNQRGNGWYLIVGISTEINADTYVDTLQLQGMRDKTKVYDQCIQIGSGRLKQ
>NZ_CP031098.1|WP_003357973.1|3527207_3527642_+|hypothetical-protein
MDLNRIKDFKVDLLYEDGKNTGGVITNYKPPRPAYFRKGIRTVQGYTYFEKNIKSDCIIEFTVAFNIKGENDEKTQSNITKFLNFRKNYSGRFIFIDEFGIQYKGYLQNKFEIDTPIEGDIYYINLELLCNHEASGWVKDNDKV
>NZ_CP031098.1|WP_003357715.1|3525791_3527195_+|hypothetical-protein
MAVNVGEAVAHLTLDTSEFKKALNGAGKDLEIFVHKVEKEKTRIEKLQEALAKEAGTLSKIGKSMEKPSAAAQNLLKTGMKNTLAEEAKSKNPKKGPANIAKGNYDKIQKDIQASIKKVQDSFAQLQTSIVKQLIPIFNNQLVPILNNKLIPIFTKLANKAVELMNSFNKLPNPVKNAIAIIIVSIAGVAKTFTVLSKLVGTINNVIGIFGKLKKAGGIFGLLKTIITSKTLLILVAIAAIGLIVYEVIKHWDQLKKAADDLGKKISNVCKKISGHFDKNIKKWKIKWKAFRTYMHKIGQDIMRGLVSGLKEGIKKVRETIESIANEIKNRFKKMLGINSPSRVFADYGNFIGEGLIQGIDNQESAINNKFKGIANKIKGLGNVRPNFNGLNNMSLSGAYGGTYASPYGPNNMNKSMGLTQDIKMYVTIPNADKEGANKIANEFKQMTESSMKNVMTGLFMNDVLRD
>NZ_CP031098.1|WP_162265969.1|3525385_3525628_+|hypothetical-protein
MKSQRILSVISISRQYRQRPSEIIGLTNDYEAFCFDEACVYILNEISKEDAREPKFIDGDRTNKTNNEDVIQWLNANNKS
>NZ_CP031098.1|WP_003357967.1|3525009_3525426_+|hypothetical-protein
MDLKVTNIEDLKKVAQGEVIQLPQFGQGIPFNARVKRVSLLNLVRKGVVPNKLLSAAEELFYGKQSSKENVDLTQMTDVMYIMAENALVEPSIEDLKSVELELTDEQIVALFNYTQEGVSELDSFREESENTECNINK
>NZ_CP031098.1|WP_003357852.1|3524107_3524995_+|hypothetical-protein
MTSGKTLVNVVKVNFIDEVTNTKHTIETSNEIDIEPINSKGKRDILRIKNKIYGINETDDIVIGYKLKMKDNLFNIETMALIDGGTIQDNKYCGTEVGIAVERHPFTMEIFTEEKDYSRTTGYVKFVYKHCKGKPAKYKIQDGKFLVSSYEAESIPFRNEKPVEIEFINKLEENDNGEKPGESTPIEDIGVEGGEVENKNPDVGVSITNRVVWNFSNQINQDDVNLENFIIKRKSDNSRVNGNATIDDTKKIVTFVPDSLAIDTVYIAEAKEINKLHGSGKTTALSTEFKTIKIR
>NZ_CP031098.1|WP_003358083.1|3534977_3535253_+|hypothetical-protein
MAYGRNEFGYYEEYQAVASSNQGSFNNPRQKMWTVQRRGYYAWEIELITNSFEDAKDKARFLLDCGGEYMNINRVMVSEIVPMDNVITPSV
>NZ_CP031098.1|WP_003358057.1|3535264_3536263_+|hypothetical-protein
MKLIQVKNGLLEAENFFLASSFSDFAGESNVTRDIKAGKLKLISNNKMERKFDYKEFVLEVEKENFNDIKDMDYSMLYLGNGDYIFGIKDLKSNEQNRYWKILKKDNYIQAYSSNDGKSYINIGGIKFIEPLTKQGFMKYSDEDFILNNYKVYANPYVTIQNFPENTLCELYDLDNNLIKTRLFNSDMECKVLIDGNMEGYFTFKDMDGKMIYTSDAIQLQYGDMWVFSPYNFEIIYHGNVVTNVSPAMLQDLEELITIKNIGDKDYNNIKIGTETPSNDLIQLSFDGINYTDSLTINSIKQHESKGIYVKITKNAENHNFAVRDFHLVISE
>NZ_CP031098.1|WP_003358123.1|3536274_3537360_+|hypothetical-protein
MSEFFNVTLDKDIILDDSVISNKTGWSSEKIQKEIIDKRITKFEELEDVDVTNKKNKQLVAYSEETGKFTTIDGIDAGEIVGAGMKQISKMGIVGSAETPRIVNIPVNTVDFKVPRVNVLRYDTENTQDLISVKNEFTNDESNDFIDDKMITFDGKAHLETNHISDFEVVQDTESFTEYSVNVDKTLFKRIEGFETFEDGVIQKLRTKAIPFDRLLIPKGDMNLSNVDHIDYFRLTANGNNIRIVCSVDSGNTWKTFSGEKWVNVNLTVDDVRKNGMNIDIFNAINDVFWNELVTTKKIRFAYLFSMDNITDIEEIDKLDLQYDGVGRWKQVKEDLYEVIYASNTLLQVECKFSGDIKINY
>NZ_CP031098.1|WP_003358023.1|3537392_3538310_+|hypothetical-protein
MGIIFQDAFDTGAVLDKNKWEINTLNGYDVILENGKLKFSATGSWCGAYVHPRVKINKNKIGPKGLSIEFDYTIGNHYSSADKPYVGFYNASKTPIRDNRYNMIQCDGINSFLIYLADNSDSSKRTKFSMAYTNKLLKTVSVNYSVGEILHIKLLLNKNKKNISMFIDNEEAPLLVCDIPNWDSLGEELIFEINSNSYSRFVEYYDNFIIKNIAEYRYLLEQDNQYYSLKSQFYKGGQFQPITELNEKETLIQSDFETYGIDDLNSLTKTIDTQDINGIDKGNLGNGKLFEIPFSNDFLNISEVE
>NZ_CP031098.1|WP_003393065.1|3538312_3539092_+|discoidin-domain-containing-protein
MAKYTENLIPKMTSDSINGITVSASADYGNSFKAWNAFDRDSNKYWVAGHSISIGWLKVNFGINNEREISKYTIKHFNNAPYINSAPRDWTFEGSNDNINWNILDVRNNEINWKLNEQREYTFKNFNKYQYYRLNISRNNGSQYVSIDEIEMMESININKYLIKEKNQYYTIDNIEIILSSSQTLDEDNFNNNGFNDIDILTKDLLLSKFKNLEEVKLLVYTDDLEKNKCEMIYNCEPFRPIDVLKKNSDYCKVLFKEV
>NZ_CP031098.1|WP_003357911.1|3539143_3539911_+|hypothetical-protein
MYYYMLKIDNIYPSPYNICMISKIQTSTTNTELKYVSVDSYEYTGDGTGAFQEDAGNRRWQTNRSSSFPHYIIFSSNKLLNDIIIKTGSKSEGGFSAKNFSLYISNEKLSYSSTAWNKLFEGTFDNNDNDQFFILQKFKYLIRQNENYYSINNSYINLGQVDADDELNDLLDNYGYDDLSFIITKELDNKLIPTKLKDTGYYESFDINLNDVKDNIMLFQENDKKYIQYNCDPYKILDEIKKINDGKFGIVMKKE
>NZ_CP031098.1|WP_003358070.1|3539976_3540801_+|discoidin-domain-containing-protein
MKIKYTENLIPKMTSNTTPIGKCKASTTYGTTWEAWKAFNDTCVDGDDCWATTNKNSWLSYEFLEPIIINKYSICPRNSGDFNTASPKNWSFEGSNNGLDWGKLDTRKDITNWQLMRNNEFIFNNNIPYKIYKINIFDNNGGYYLCIGKLCMMSKITYNKYLLKQNSNYYSIDNNYMDLGTINNDEELYNVIDEYGYDDLSILTKELNNKKVPTKLENDYYKYFDIDLNDIKDNINLIEENDKKYIEYGCNNYKISDKIKEINNAKFEILMKEY
>NZ_CP031098.1|WP_003357870.1|3540866_3541676_+|hypothetical-protein
MKKWSNDLTDSLKQENFTSSRLHTGRYHYIPYFAFDNHTASTIYDGFQLHYPNNMDWLKIDFINPVNPSKITIQGNDDQPYLPKKIRVLMSDNDIDYVEIDIIDNIKNDNKVTEYVYKNSTKKYRFLKIEFLEFYSTEWLSINQMQFFKAISATKYLINQNKNYYSTKSNFINLGQPTDNIQLENWYNKYGADDINIITQNLNNKEFPMSRDESGIWKTDSELDMNEVIDNIELVDTDENNKSIKYNCNDYRILDLCDDQFKLTMCKSK
>NZ_CP031098.1|WP_003358009.1|3541831_3542086_+|membrane-protein
MELKVCEEKHKRLEEKINVHDIRLNDHGKRIDKIEQNQSKIDTKIENLCDQLKQLVSVLKWYIGLSVGALVSFFFYAIQHNIFK
>NZ_CP031098.1|WP_003357959.1|3542104_3542299_+|hypothetical-protein
MEFLKKFLQIKKIIALLTTIVFCYLSIKGSLSSTEFLSVFTLIIGFYFGQSSARQAVKESKEQE

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP031098_3	3.4\|467601\|36\|NZ_CP031098\|CRT	467601-467636	36	NZ_CP031100.1	4370-4405	2	0.944

1. spacer 3.4|467601|36|NZ_CP031098|CRT matches to position: 4370-4405, mismatch: 2, identity: 0.944

tttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
tttgcttcacaccaggaacttagtccccctattgtt	Protospacer
***********************.***.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP031098_1	1.1\|450801\|36\|NZ_CP031098\|PILER-CR,CRISPRCasFinder,CRT	450801-450836	36	NZ_CP013848	Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence	6073-6108	0	1.0
NZ_CP031098_3	3.4\|467601\|36\|NZ_CP031098\|CRT	467601-467636	36	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	24348-24383	1	0.972
NZ_CP031098_3	3.4\|467601\|36\|NZ_CP031098\|CRT	467601-467636	36	NZ_CP031100	Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence	4370-4405	2	0.944
NZ_CP031098_3	3.4\|467601\|36\|NZ_CP031098\|CRT	467601-467636	36	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	26886-26921	2	0.944
NZ_CP031098_3	3.1\|467599\|38\|NZ_CP031098\|CRISPRCasFinder	467599-467636	38	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	24346-24383	3	0.921
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	MT430910	Streptococcus phage smHBZ8, complete genome	5109-5133	3	0.88
NZ_CP031098_3	3.1\|467599\|38\|NZ_CP031098\|CRISPRCasFinder	467599-467636	38	NZ_CP031100	Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence	4368-4405	4	0.895
NZ_CP031098_3	3.1\|467599\|38\|NZ_CP031098\|CRISPRCasFinder	467599-467636	38	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	26886-26923	4	0.895
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	MH598512	Bacillus phage Wes44, complete genome	8507-8531	4	0.84
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	MN693446	Marine virus AFVG_25M550, complete genome	3843-3867	4	0.84
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	NZ_KJ645709	Enterococcus faecium strain P26 plasmid pXD5, complete sequence	38961-38992	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	MK784777	Enterococcus faecalis strain E211 plasmid pE211-2, complete sequence	72924-72955	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	MT074686	Enterococcus faecium strain E1077 plasmid pE1077-217, complete sequence	123596-123627	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	NZ_CP040905	Enterococcus faecium strain N56454 plasmid unnamed, complete sequence	93007-93038	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	NZ_LR135483	Enterococcus faecium isolate E4456 plasmid 2	152564-152595	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	NZ_AP018539	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence	81746-81777	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	MH277333	UNVERIFIED: Listeria monocytogenes strain nh1 plasmid, complete sequence	47056-47087	5	0.844
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	MK465704	Enterococcus faecium strain E211 plasmid pE211-2, complete sequence	784-815	5	0.844
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_KX753679	Pasteurella multocida strain RCAD0259 plasmid pRCADGH-2, complete sequence	19038-19062	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_KU356480	Vibrio parahaemolyticus strain VPS92 plasmid pVPS92-VEB, complete sequence	279247-279271	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_KX539265	Vibrio parahaemolyticus strain VPS72 plasmid pVPS72-VEB, complete sequence	3366-3390	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_KX575838	Vibrio alginolyticus strain VAS24 plasmid pVAS24-VEB, complete sequence	3308-3332	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NC_022078	Klebsiella pneumoniae JM45 plasmid p1, complete sequence	153125-153149	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP042480	Citrobacter freundii strain C50 plasmid pC50_002, complete sequence	30136-30160	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP039991	Pseudomonas aeruginosa strain T2101 plasmid pBT2101, complete sequence	225929-225953	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP039991	Pseudomonas aeruginosa strain T2101 plasmid pBT2101, complete sequence	240295-240319	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP042484	Klebsiella pneumoniae strain C51 plasmid pC51_003, complete sequence	1540-1564	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP031802	Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed2, complete sequence	28585-28609	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP027043	Klebsiella pneumoniae strain 1_GR_13 plasmid IncAC2, complete sequence	165549-165573	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP029123	Escherichia coli strain AR434 plasmid unnamed1, complete sequence	39429-39453	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP042553	Enterobacter hormaechei strain C45 plasmid pC45_002, complete sequence	30136-30160	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP042519	Citrobacter freundii strain E33 plasmid pE33_002, complete sequence	30136-30160	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	LC542613	Klebsiella quasipneumoniae subsp. similipneumoniae MS2H7 plasmid pMS2H7VEB-1 DNA, complete sequence	18200-18224	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	LC542924	Klebsiella pneumoniae MS2H5 plasmid pMS2H5VEB-1 DNA, complete sequence	18200-18224	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_KT852971	Acinetobacter baumannii strain 255_n plasmid p255n_1 clone MLST16 (Pasteur); Clonal Complex 16; CC16, complete sequence	117-141	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_MK388209	Escherichia coli strain Ec20-Lar plasmid pC-Ec20-KPC, complete sequence	65613-65637	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_MK439959	Escherichia coli strain Ec-2Lar plasmid pC-Ec2-KPC, complete sequence	105926-105950	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	MN175386	Klebsiella pneumoniae strain KP-13-14 plasmid pKP-13-14-NDM-9, complete sequence	79058-79082	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP039989	Pseudomonas aeruginosa strain T2436 plasmid pBT2436, complete sequence	210451-210475	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP027038	Klebsiella pneumoniae strain 16_GR_13 plasmid IncAC2, complete sequence	146296-146320	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP027055	Klebsiella pneumoniae strain 2_GR_12 plasmid IncAC2	146300-146324	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP033574	Shewanella algae strain KC-Na-R1 plasmid pKC-Na-R1, complete sequence	104896-104920	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	KM506769	Uncultured bacterium plasmid pKAZ1, complete sequence	147853-147877	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	KR827391	Uncultured bacterium plasmid pKAZ2, complete sequence	174451-174475	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	KR827392	Uncultured bacterium plasmid pKAZ3, complete sequence	146114-146138	5	0.8
NZ_CP031098_4	4.1\|3534063\|25\|NZ_CP031098\|CRISPRCasFinder	3534063-3534087	25	NZ_CP013115	Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence	135298-135322	5	0.8
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	MK784777	Enterococcus faecalis strain E211 plasmid pE211-2, complete sequence	72924-72957	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	MT074686	Enterococcus faecium strain E1077 plasmid pE1077-217, complete sequence	123596-123629	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	NZ_CP040905	Enterococcus faecium strain N56454 plasmid unnamed, complete sequence	93007-93040	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	NZ_LR135483	Enterococcus faecium isolate E4456 plasmid 2	152564-152597	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	MH277333	UNVERIFIED: Listeria monocytogenes strain nh1 plasmid, complete sequence	47056-47089	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	MK465704	Enterococcus faecium strain E211 plasmid pE211-2, complete sequence	784-817	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	NZ_KJ645709	Enterococcus faecium strain P26 plasmid pXD5, complete sequence	38959-38992	7	0.794
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	NZ_AP018539	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence	81744-81777	7	0.794
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	MN694574	Marine virus AFVG_250M706, complete genome	34787-34818	7	0.781
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	AP014183	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C67-MedDCM-OCT-S42-C67, * SEQUENCING IN PROGRESS *	17750-17781	8	0.75
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	AP014183	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C67-MedDCM-OCT-S42-C67, * SEQUENCING IN PROGRESS *	17748-17781	9	0.735
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	MF417901	Uncultured Caudovirales phage clone 9S_1, partial genome	35308-35341	9	0.735
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	MF417982	Uncultured Caudovirales phage clone 7F_2, partial genome	716-749	9	0.735
NZ_CP031098_3	3.7\|467668\|32\|NZ_CP031098\|PILER-CR	467668-467699	32	MT500540	Listeria phage LP-HM00113468, complete genome	39251-39282	9	0.719
NZ_CP031098_3	3.7\|467668\|32\|NZ_CP031098\|PILER-CR	467668-467699	32	MH552526	Siphoviridae sp. isolate ctfj46, complete genome	45312-45343	9	0.719
NZ_CP031098_3	3.7\|467668\|32\|NZ_CP031098\|PILER-CR	467668-467699	32	KJ094023	Listeria phage LP-101, complete genome	5670-5701	9	0.719
NZ_CP031098_3	3.8\|467732\|32\|NZ_CP031098\|PILER-CR	467732-467763	32	CP002965	Emticicia oligotrophica DSM 17448 plasmid pEMTOL04, complete sequence	14987-15018	9	0.719
NZ_CP031098_3	3.7\|467668\|32\|NZ_CP031098\|PILER-CR	467668-467699	32	MN694764	Marine virus AFVG_250M267, complete genome	36367-36398	10	0.688
NZ_CP031098_2	2.2\|453896\|35\|NZ_CP031098\|PILER-CR,CRISPRCasFinder,CRT	453896-453930	35	MN694165	Marine virus AFVG_250M579, complete genome	4526-4560	11	0.686
NZ_CP031098_3	3.6\|467731\|34\|NZ_CP031098\|CRT	467731-467764	34	CP002965	Emticicia oligotrophica DSM 17448 plasmid pEMTOL04, complete sequence	14987-15020	11	0.676

1. spacer 1.1|450801|36|NZ_CP031098|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013848 (Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence) position: , mismatch: 0, identity: 1.0

tcctccatatctcacatatcctttctaaaacatttc	CRISPR spacer
tcctccatatctcacatatcctttctaaaacatttc	Protospacer
************************************

2. spacer 3.4|467601|36|NZ_CP031098|CRT matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 1, identity: 0.972

tttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
tttgcttcacaccaggagcttagcccctctattgtt	Protospacer
*****************.******************

3. spacer 3.4|467601|36|NZ_CP031098|CRT matches to NZ_CP031100 (Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence) position: , mismatch: 2, identity: 0.944

tttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
tttgcttcacaccaggaacttagtccccctattgtt	Protospacer
***********************.***.********

4. spacer 3.4|467601|36|NZ_CP031098|CRT matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 2, identity: 0.944

tttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
tttgcttcacaccaggagcttatcccctctattgtt	Protospacer
*****************.**** *************

5. spacer 3.1|467599|38|NZ_CP031098|CRISPRCasFinder matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 3, identity: 0.921

attttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
catttgcttcacaccaggagcttagcccctctattgtt	Protospacer
  *****************.******************

6. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 3, identity: 0.88

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatttcaaccaatatttttaaa	Protospacer
******* *********** ***.*

7. spacer 3.1|467599|38|NZ_CP031098|CRISPRCasFinder matches to NZ_CP031100 (Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence) position: , mismatch: 4, identity: 0.895

attttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
gatttgcttcacaccaggaacttagtccccctattgtt	Protospacer
. ***********************.***.********

8. spacer 3.1|467599|38|NZ_CP031098|CRISPRCasFinder matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 4, identity: 0.895

attttgcttcacaccaggaacttagcccctctattgtt	CRISPR spacer
catttgcttcacaccaggagcttatcccctctattgtt	Protospacer
  *****************.**** *************

9. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to MH598512 (Bacillus phage Wes44, complete genome) position: , mismatch: 4, identity: 0.84

aaatattacaaccaatattgttaga	CRISPR spacer
ttctattacaaccaatatagttaga	Protospacer
   *************** ******

10. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to MN693446 (Marine virus AFVG_25M550, complete genome) position: , mismatch: 4, identity: 0.84

aaatattacaaccaatattgttaga	CRISPR spacer
taatattagaaccaatattgtttca	Protospacer
 ******* *************  *

11. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to NZ_KJ645709 (Enterococcus faecium strain P26 plasmid pXD5, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

12. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to MK784777 (Enterococcus faecalis strain E211 plasmid pE211-2, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

13. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to MT074686 (Enterococcus faecium strain E1077 plasmid pE1077-217, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

14. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to NZ_CP040905 (Enterococcus faecium strain N56454 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

15. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to NZ_LR135483 (Enterococcus faecium isolate E4456 plasmid 2) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

16. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to NZ_AP018539 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

17. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to MH277333 (UNVERIFIED: Listeria monocytogenes strain nh1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

18. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to MK465704 (Enterococcus faecium strain E211 plasmid pE211-2, complete sequence) position: , mismatch: 5, identity: 0.844

-aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatca	Protospacer
 **** .* ********.********.******

19. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_KX753679 (Pasteurella multocida strain RCAD0259 plasmid pRCADGH-2, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

20. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_KU356480 (Vibrio parahaemolyticus strain VPS92 plasmid pVPS92-VEB, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

21. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_KX539265 (Vibrio parahaemolyticus strain VPS72 plasmid pVPS72-VEB, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

22. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_KX575838 (Vibrio alginolyticus strain VAS24 plasmid pVAS24-VEB, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

23. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NC_022078 (Klebsiella pneumoniae JM45 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

24. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP042480 (Citrobacter freundii strain C50 plasmid pC50_002, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

25. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP039991 (Pseudomonas aeruginosa strain T2101 plasmid pBT2101, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

26. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP039991 (Pseudomonas aeruginosa strain T2101 plasmid pBT2101, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

27. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP042484 (Klebsiella pneumoniae strain C51 plasmid pC51_003, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

28. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP031802 (Klebsiella pneumoniae strain MSB1_8A-sc-2280397 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

29. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP027043 (Klebsiella pneumoniae strain 1_GR_13 plasmid IncAC2, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

30. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP029123 (Escherichia coli strain AR434 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

31. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP042553 (Enterobacter hormaechei strain C45 plasmid pC45_002, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

32. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP042519 (Citrobacter freundii strain E33 plasmid pE33_002, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

33. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to LC542613 (Klebsiella quasipneumoniae subsp. similipneumoniae MS2H7 plasmid pMS2H7VEB-1 DNA, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

34. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to LC542924 (Klebsiella pneumoniae MS2H5 plasmid pMS2H5VEB-1 DNA, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

35. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_KT852971 (Acinetobacter baumannii strain 255_n plasmid p255n_1 clone MLST16 (Pasteur); Clonal Complex 16; CC16, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

36. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_MK388209 (Escherichia coli strain Ec20-Lar plasmid pC-Ec20-KPC, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

37. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_MK439959 (Escherichia coli strain Ec-2Lar plasmid pC-Ec2-KPC, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

38. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to MN175386 (Klebsiella pneumoniae strain KP-13-14 plasmid pKP-13-14-NDM-9, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

39. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP039989 (Pseudomonas aeruginosa strain T2436 plasmid pBT2436, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

40. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP027038 (Klebsiella pneumoniae strain 16_GR_13 plasmid IncAC2, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

41. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP027055 (Klebsiella pneumoniae strain 2_GR_12 plasmid IncAC2) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

42. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP033574 (Shewanella algae strain KC-Na-R1 plasmid pKC-Na-R1, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

43. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to KM506769 (Uncultured bacterium plasmid pKAZ1, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

44. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to KR827391 (Uncultured bacterium plasmid pKAZ2, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

45. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to KR827392 (Uncultured bacterium plasmid pKAZ3, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

46. spacer 4.1|3534063|25|NZ_CP031098|CRISPRCasFinder matches to NZ_CP013115 (Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence) position: , mismatch: 5, identity: 0.8

aaatattacaaccaatattgttaga	CRISPR spacer
aaatatcacaaccaatattgtcgct	Protospacer
******.**************..

47. spacer 3.6|467731|34|NZ_CP031098|CRT matches to MK784777 (Enterococcus faecalis strain E211 plasmid pE211-2, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

48. spacer 3.6|467731|34|NZ_CP031098|CRT matches to MT074686 (Enterococcus faecium strain E1077 plasmid pE1077-217, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

49. spacer 3.6|467731|34|NZ_CP031098|CRT matches to NZ_CP040905 (Enterococcus faecium strain N56454 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

50. spacer 3.6|467731|34|NZ_CP031098|CRT matches to NZ_LR135483 (Enterococcus faecium isolate E4456 plasmid 2) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

51. spacer 3.6|467731|34|NZ_CP031098|CRT matches to MH277333 (UNVERIFIED: Listeria monocytogenes strain nh1 plasmid, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

52. spacer 3.6|467731|34|NZ_CP031098|CRT matches to MK465704 (Enterococcus faecium strain E211 plasmid pE211-2, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

53. spacer 3.6|467731|34|NZ_CP031098|CRT matches to NZ_KJ645709 (Enterococcus faecium strain P26 plasmid pXD5, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

54. spacer 3.6|467731|34|NZ_CP031098|CRT matches to NZ_AP018539 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-1, complete sequence) position: , mismatch: 7, identity: 0.794

-aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
caaattca-tcatcttcaatatttgtctcatcagt	Protospacer
 **** .* ********.********.******..

55. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to MN694574 (Marine virus AFVG_250M706, complete genome) position: , mismatch: 7, identity: 0.781

---aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
ttgaagt---ttgatcttcgatatttgtttcatat	Protospacer
   **.*   ** ********************

56. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to AP014183 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C67-MedDCM-OCT-S42-C67, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.75

aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
cctcatattcatcttcgatattgttttcaata	Protospacer
   .******************  ***** .*

57. spacer 3.6|467731|34|NZ_CP031098|CRT matches to AP014183 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C67-MedDCM-OCT-S42-C67, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.735

aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
cctcatattcatcttcgatattgttttcaatatc	Protospacer
   .******************  ***** .* *

58. spacer 3.6|467731|34|NZ_CP031098|CRT matches to MF417901 (Uncultured Caudovirales phage clone 9S_1, partial genome) position: , mismatch: 9, identity: 0.735

aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
gagtgcttctatctttgatatttgttacatcaac	Protospacer
.*.*.. *..*****.********** *******

59. spacer 3.6|467731|34|NZ_CP031098|CRT matches to MF417982 (Uncultured Caudovirales phage clone 7F_2, partial genome) position: , mismatch: 9, identity: 0.735

aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
gagtgcttctatctttgatatttgttacatcaac	Protospacer
.*.*.. *..*****.********** *******

60. spacer 3.7|467668|32|NZ_CP031098|PILER-CR matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 9, identity: 0.719

tcaaatagaattacattttctatgataaaatt-------	CRISPR spacer
tcgaatagaattactttttctat-------ttcacctgg	Protospacer
**.*********** ********       **

61. spacer 3.7|467668|32|NZ_CP031098|PILER-CR matches to MH552526 (Siphoviridae sp. isolate ctfj46, complete genome) position: , mismatch: 9, identity: 0.719

tcaaatagaattacattttctatg----ataaaatt	CRISPR spacer
ccaaatttaattacattttctatgtcttgcaa----	Protospacer
.*****  ****************    ..**

62. spacer 3.7|467668|32|NZ_CP031098|PILER-CR matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 9, identity: 0.719

tcaaatagaattacattttctatgataaaatt-------	CRISPR spacer
tcgaatagaattactttttctat-------ttcacctgg	Protospacer
**.*********** ********       **

63. spacer 3.8|467732|32|NZ_CP031098|PILER-CR matches to CP002965 (Emticicia oligotrophica DSM 17448 plasmid pEMTOL04, complete sequence) position: , mismatch: 9, identity: 0.719

aaatatattcatcttcgatatttgtttcatca	CRISPR spacer
gtttttattcttcttcgatttttgtttcaatt	Protospacer
.  * ***** ******** ********* .

64. spacer 3.7|467668|32|NZ_CP031098|PILER-CR matches to MN694764 (Marine virus AFVG_250M267, complete genome) position: , mismatch: 10, identity: 0.688

tcaaatagaattacattttctatgataaaatt	CRISPR spacer
acggcctcaattagattttctctgataaaatc	Protospacer
 *.. .  ***** ******* *********.

65. spacer 2.2|453896|35|NZ_CP031098|PILER-CR,CRISPRCasFinder,CRT matches to MN694165 (Marine virus AFVG_250M579, complete genome) position: , mismatch: 11, identity: 0.686

cgtttttttgttgcaggttttattaaaagtaatag	CRISPR spacer
acaatagttgttgtatgttttattaaaagtaaagt	Protospacer
    *  ******.* **************** .

66. spacer 3.6|467731|34|NZ_CP031098|CRT matches to CP002965 (Emticicia oligotrophica DSM 17448 plasmid pEMTOL04, complete sequence) position: , mismatch: 11, identity: 0.676

aaatatattcatcttcgatatttgtttcatcaac	CRISPR spacer
gtttttattcttcttcgatttttgtttcaatttt	Protospacer
.  * ***** ******** ********* .  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1028624 : 1036828

uncultured_Caudovirales_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003358601.1\|1028624_1029581_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.2e-14	38.6
WP_003358688.1\|1029727_1030546_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003358784.1\|1030847_1031498_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.7e-59	51.2
WP_003358544.1\|1031681_1032272_-	GTP cyclohydrolase I FolE	S4U0J3	uncultured_phage	9.8e-46	54.5
WP_003358633.1\|1032275_1032941_-	putative 7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	1.4e-37	44.6
WP_003358723.1\|1032942_1033374_-	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	1.4e-12	33.1
WP_003358645.1\|1033391_1034153_-	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
WP_003358556.1\|1034269_1035265_-	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
WP_003358714.1\|1035883_1036828_+	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	3.2e-14	31.1

DBSCAN-SWA_2

1344434 : 1384444

Clostridium_phage(52.5%)

capsid,plate,terminase,portal,tail,integrase

attL 1370043:1370060|attR 1388678:1388695

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003356732.1\|1344434_1345202_-	SH3 domain-containing protein	A0A2H4J8A3	uncultured_Caudovirales_phage	3.5e-88	65.1
WP_003356211.1\|1345241_1345436_-	hypothetical protein	NA	NA	NA	NA
WP_003357220.1\|1345452_1345707_-	membrane protein	A0A0A7RTX0	Clostridium_phage	9.1e-25	68.4
WP_003356540.1\|1345802_1346147_-	hypothetical protein	A0A2H4JGH3	uncultured_Caudovirales_phage	6.4e-05	60.0
WP_003356147.1\|1346414_1346819_-	hypothetical protein	NA	NA	NA	NA
WP_003356858.1\|1347228_1347573_-	hypothetical protein	A0A2H4J342	uncultured_Caudovirales_phage	1.8e-31	62.6
WP_003356966.1\|1347583_1348765_-\|tail	phage tail protein	A0A2H4J039	uncultured_Caudovirales_phage	4.6e-71	62.3
WP_003356868.1\|1348768_1349395_-	DUF2313 domain-containing protein	A0A0A7RVP9	Clostridium_phage	4.6e-86	74.1
WP_003355953.1\|1349375_1350470_-\|plate	baseplate J/gp47 family protein	A0A0A7S096	Clostridium_phage	4.0e-162	77.5
WP_003356660.1\|1350473_1350881_-	DUF2634 domain-containing protein	A0A0A7RTH1	Clostridium_phage	3.6e-55	84.6
WP_003356627.1\|1350883_1351228_-	DUF2577 domain-containing protein	A0A0A7RTJ2	Clostridium_phage	6.3e-37	73.7
WP_003355762.1\|1351230_1352205_-	hypothetical protein	A0A0A7RTZ4	Clostridium_phage	1.6e-157	84.9
WP_003356924.1\|1352216_1352885_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7RVP5	Clostridium_phage	2.0e-95	75.0
WP_031367384.1\|1352884_1354909_-	hypothetical protein	A0A0A7S091	Clostridium_phage	6.8e-155	51.4
WP_003356953.1\|1354949_1355627_-	hypothetical protein	NA	NA	NA	NA
WP_003356777.1\|1355884_1356298_-	hypothetical protein	A0A0A7RTN3	Clostridium_phage	1.1e-51	74.8
WP_003356607.1\|1356313_1356778_-\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	1.9e-73	87.7
WP_003356497.1\|1356781_1358092_-	hypothetical protein	A0A0A7S087	Clostridium_phage	5.5e-214	85.8
WP_003356354.1\|1358253_1358712_-	hypothetical protein	A0A0A7RTI2	Clostridium_phage	3.8e-53	76.2
WP_003356102.1\|1358698_1359190_-	HK97 gp10 family phage protein	A0A0A7RTT0	Clostridium_phage	2.4e-61	74.1
WP_003356756.1\|1359189_1359576_-	hypothetical protein	A0A0A7S083	Clostridium_phage	7.8e-44	75.2
WP_031367383.1\|1359577_1359922_-	hypothetical protein	A0A0A7RTX9	Clostridium_phage	6.3e-45	77.2
WP_003355814.1\|1359941_1361009_-	hypothetical protein	A0A0A7RTH8	Clostridium_phage	1.7e-181	88.7
WP_003356226.1\|1361031_1361601_-	scaffold protein	A0A0A7RTM5	Clostridium_phage	1.8e-33	52.1
WP_003357135.1\|1361619_1361979_-	hypothetical protein	A0A2H4J4N9	uncultured_Caudovirales_phage	1.8e-50	82.4
WP_003356965.1\|1362093_1362366_-	hypothetical protein	NA	NA	NA	NA
WP_003356283.1\|1362432_1363455_-\|capsid	minor capsid protein	A0A0A7RVY7	Clostridium_phage	1.0e-151	78.2
WP_003355796.1\|1363444_1364887_-\|portal	phage portal protein	A0A0A7S074	Clostridium_phage	4.7e-251	89.1
WP_003356486.1\|1364899_1366309_-\|terminase	phage terminase large subunit	A0A0A7RTS1	Clostridium_phage	3.2e-212	87.9
WP_003356852.1\|1366301_1366877_-\|terminase	terminase small subunit	Q6SED9	Lactobacillus_prophage	2.9e-10	31.6
WP_003356019.1\|1366975_1367167_-	hypothetical protein	NA	NA	NA	NA
WP_003356664.1\|1367352_1367790_-	siderophore-interacting protein	A0A2H4J015	uncultured_Caudovirales_phage	5.2e-20	40.4
WP_003356993.1\|1368154_1368334_-	hypothetical protein	NA	NA	NA	NA
WP_003355742.1\|1368363_1370229_-	primase	A0A2H4J1M0	uncultured_Caudovirales_phage	0.0e+00	88.2
1370043:1370060	attL	NA	NA	NA	NA
WP_003356867.1\|1370255_1371245_-	hypothetical protein	NA	NA	NA	NA
WP_003355773.1\|1371241_1371565_-	hypothetical protein	NA	NA	NA	NA
WP_003356576.1\|1371567_1371897_-	nucleoside triphosphate pyrophosphohydrolase family protein	A0A2H4J7H8	uncultured_Caudovirales_phage	5.1e-44	78.0
WP_003355908.1\|1371897_1372167_-	DUF1599 domain-containing protein	A0A2H4J4N1	uncultured_Caudovirales_phage	3.3e-33	82.8
WP_031367224.1\|1372352_1372568_-	hypothetical protein	NA	NA	NA	NA
WP_003356217.1\|1372596_1372914_-	hypothetical protein	NA	NA	NA	NA
WP_003356709.1\|1372958_1374653_-	hypothetical protein	A0A2H4J041	uncultured_Caudovirales_phage	3.8e-292	84.6
WP_003356587.1\|1374652_1374817_-	hypothetical protein	NA	NA	NA	NA
WP_003355843.1\|1374869_1375328_-	DUF669 domain-containing protein	A0A2H4J1S8	uncultured_Caudovirales_phage	3.3e-57	66.7
WP_003357073.1\|1375330_1375651_-	hypothetical protein	NA	NA	NA	NA
WP_003356243.1\|1375650_1377333_-	AAA family ATPase	A0A2H4J7Q2	uncultured_Caudovirales_phage	1.3e-215	74.1
WP_003356700.1\|1377378_1377675_-	VRR-NUC domain-containing protein	A0A2H4J095	uncultured_Caudovirales_phage	1.1e-40	80.2
WP_003356400.1\|1377747_1378572_-	DUF1351 domain-containing protein	A0A2H4J082	uncultured_Caudovirales_phage	2.9e-96	67.9
WP_031367223.1\|1378572_1379673_-	DEAD/DEAH box helicase	A0A2H4J064	uncultured_Caudovirales_phage	2.4e-170	78.5
WP_003357026.1\|1380017_1380311_-	hypothetical protein	NA	NA	NA	NA
WP_003356023.1\|1380330_1381080_-	hypothetical protein	Q332L4	Clostridium_botulinum_C_phage	1.0e-15	36.6
WP_003356844.1\|1381096_1381426_-	hypothetical protein	NA	NA	NA	NA
WP_003355789.1\|1381425_1381629_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003356555.1\|1381837_1382350_+	helix-turn-helix domain-containing protein	A0A0A7RTK4	Clostridium_phage	6.1e-12	29.5
WP_003355973.1\|1382397_1382814_+	ImmA/IrrE family metallo-endopeptidase	I3VYZ2	Thermoanaerobacterium_phage	2.4e-06	30.1
WP_003357131.1\|1383373_1384444_+\|integrase	site-specific integrase	B3GVW7	Streptococcus_phage	1.5e-31	33.1
1388678:1388695	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3515090 : 3547393

Clostridium_phage(74.07%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003357882.1\|3515090_3516578_-	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	4.3e-66	38.3
WP_003358005.1\|3518123_3518534_-	helix-turn-helix domain-containing protein	A0A0A7RUJ5	Clostridium_phage	1.0e-09	56.2
WP_003357707.1\|3518725_3518935_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003358080.1\|3518996_3519209_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003357946.1\|3519302_3520208_+	hypothetical protein	A8ASN4	Listeria_phage	4.2e-40	40.2
WP_003357809.1\|3520197_3520998_+	ATP-binding protein	A0A2K9V3L7	Faecalibacterium_phage	3.4e-33	35.2
WP_003357794.1\|3521054_3521375_+	hypothetical protein	NA	NA	NA	NA
WP_003358043.1\|3521488_3522010_+	hypothetical protein	A0A0A7RVS1	Clostridium_phage	3.6e-36	50.6
WP_003357791.1\|3522676_3522961_+	hypothetical protein	A0A0A7S0R4	Clostridium_phage	3.0e-24	59.2
WP_003357709.1\|3522960_3523326_+	hypothetical protein	A0A0A7RW73	Clostridium_phage	1.2e-33	57.9
WP_003357847.1\|3523330_3523678_+	hypothetical protein	A0A0A7RU51	Clostridium_phage	7.8e-35	58.9
WP_003357924.1\|3523683_3524103_+	hypothetical protein	A0A0A7RU17	Clostridium_phage	1.1e-56	71.9
WP_003357852.1\|3524107_3524995_+	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	1.2e-119	75.0
WP_003357967.1\|3525009_3525426_+	hypothetical protein	A0A0A7S0S0	Clostridium_phage	9.0e-46	71.2
WP_162265969.1\|3525385_3525628_+	hypothetical protein	A0A0A7RW80	Clostridium_phage	9.9e-21	66.2
WP_003357715.1\|3525791_3527195_+	hypothetical protein	A0A0A7RU22	Clostridium_phage	5.2e-05	42.4
WP_003357973.1\|3527207_3527642_+	hypothetical protein	NA	NA	NA	NA
WP_003357869.1\|3527628_3528714_+	hypothetical protein	NA	NA	NA	NA
WP_003357831.1\|3528726_3529068_+	hypothetical protein	A0A0A7S0S4	Clostridium_phage	2.1e-16	55.7
WP_003358000.1\|3529082_3530432_+	caspase family protein	A0A0A7RW86	Clostridium_phage	2.1e-75	74.6
WP_003358129.1\|3530433_3531411_+	hypothetical protein	A0A0A7RU61	Clostridium_phage	9.3e-110	60.2
WP_003357799.1\|3531433_3532942_+	hypothetical protein	A0A0A7RU28	Clostridium_phage	5.5e-93	37.7
WP_003357733.1\|3532953_3534975_+	hypothetical protein	A0A0A7RU09	Clostridium_phage	1.1e-56	48.5
WP_003358083.1\|3534977_3535253_+	hypothetical protein	A0A223LE82	Bacillus_phage	3.9e-05	38.8
WP_003358057.1\|3535264_3536263_+	hypothetical protein	A0A0A7RW91	Clostridium_phage	2.1e-141	72.6
WP_003358123.1\|3536274_3537360_+	hypothetical protein	A0A0A7RU66	Clostridium_phage	4.2e-143	70.4
WP_003358023.1\|3537392_3538310_+	hypothetical protein	NA	NA	NA	NA
WP_003393065.1\|3538312_3539092_+	discoidin domain-containing protein	NA	NA	NA	NA
WP_003357911.1\|3539143_3539911_+	hypothetical protein	NA	NA	NA	NA
WP_003358070.1\|3539976_3540801_+	discoidin domain-containing protein	A0A0A7RU33	Clostridium_phage	7.3e-15	30.4
WP_003357870.1\|3540866_3541676_+	hypothetical protein	A0A0A7RU33	Clostridium_phage	2.8e-27	34.7
WP_003358009.1\|3541831_3542086_+	membrane protein	A0A0A7RTX0	Clostridium_phage	4.8e-26	70.9
WP_003357959.1\|3542104_3542299_+	hypothetical protein	NA	NA	NA	NA
WP_003357964.1\|3542445_3543225_+	SH3 domain-containing protein	A0A2H4J8A3	uncultured_Caudovirales_phage	1.2e-88	63.4
WP_003357751.1\|3543623_3544748_+	chorismate synthase	A0A291AU41	Pandoravirus	3.8e-30	28.5
WP_003357975.1\|3544765_3547393_+	DNA polymerase I	F8WQ35	Bacillus_phage	4.2e-64	35.4

DBSCAN-SWA_4

3563422 : 3651374

Clostridium_phage(76.0%)

plate,terminase,portal,transposase,holin,head,tRNA,tail,integrase,protease

attL 3583377:3583436|attR 3627822:3627882

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003358144.1\|3563422_3564274_+\|protease	metalloprotease	NA	NA	NA	NA
WP_003357979.1\|3564386_3566237_+	TIGR03960 family B12-binding radical SAM protein	NA	NA	NA	NA
WP_003357739.1\|3566214_3566928_+	DUF2344 domain-containing protein	NA	NA	NA	NA
WP_003358087.1\|3566966_3568406_+	ribonuclease E/G	NA	NA	NA	NA
WP_003357920.1\|3568529_3568844_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_003357900.1\|3568846_3569173_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003357774.1\|3569175_3569478_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_003357748.1\|3569856_3571131_+	GTPase ObgE	NA	NA	NA	NA
WP_003358089.1\|3571157_3571451_+	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_003357933.1\|3571693_3572299_+	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_003357821.1\|3572381_3572951_+	HD domain-containing protein	NA	NA	NA	NA
WP_003358143.1\|3572961_3574236_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	1.7e-18	29.2
WP_003357849.1\|3574251_3574632_+	RidA family protein	NA	NA	NA	NA
WP_003357985.1\|3574957_3575860_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_003357731.1\|3575967_3577215_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_003358042.1\|3577403_3578012_+	DNA-binding protein	NA	NA	NA	NA
WP_093461105.1\|3578117_3579197_+	selenide, water dikinase SelD	NA	NA	NA	NA
WP_003358076.1\|3579263_3580652_+\|tRNA	L-seryl-tRNA(Sec) selenium transferase	NA	NA	NA	NA
WP_003358142.1\|3580670_3582578_+	selenocysteine-specific translation elongation factor	A0A2K9KZ60	Tupanvirus	2.8e-17	30.9
3583377:3583436	attL	NA	NA	NA	NA
WP_003357815.1\|3583553_3584717_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	5.3e-35	31.4
WP_003357740.1\|3584765_3585218_-	ImmA/IrrE family metallo-endopeptidase	I3VYZ2	Thermoanaerobacterium_phage	6.2e-16	40.0
WP_003357840.1\|3585226_3585661_-	helix-turn-helix transcriptional regulator	M9Q2L3	Clostridium_phage	9.5e-14	39.1
WP_003358015.1\|3585878_3586073_+	helix-turn-helix transcriptional regulator	A0A0A8WE47	Clostridium_phage	6.1e-05	36.5
WP_003358119.1\|3586090_3586351_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_003358071.1\|3586365_3586545_+	hypothetical protein	NA	NA	NA	NA
WP_003398780.1\|3586758_3587040_+	hypothetical protein	A0A0A7RTW4	Clostridium_phage	1.0e-21	63.8
WP_003357951.1\|3587092_3587446_+	hypothetical protein	A0A0A7RVM0	Clostridium_phage	3.4e-38	69.8
WP_003357939.1\|3587463_3587709_+	hypothetical protein	A0A0A7RTK9	Clostridium_phage	1.1e-24	65.0
WP_003357853.1\|3587742_3588192_+	hypothetical protein	A0A0A7RTD8	Clostridium_phage	1.9e-09	50.9
WP_003357764.1\|3588191_3589337_+	DUF2800 domain-containing protein	A0A0A7S066	Clostridium_phage	5.0e-195	88.5
WP_003358058.1\|3589348_3589969_+	DUF2815 family protein	A0A0A7RVM4	Clostridium_phage	6.8e-90	85.5
WP_003357884.1\|3590139_3592101_+	DNA polymerase	A0A0A7RTL3	Clostridium_phage	3.3e-279	72.4
WP_003358078.1\|3592139_3592370_+	hypothetical protein	NA	NA	NA	NA
WP_003358037.1\|3592406_3593432_+	nucleoid-associated protein	A0A090D855	Clostridium_phage	1.9e-44	33.1
WP_003357932.1\|3593477_3595904_+	virulence-associated E family protein	A0A0A7RTG3	Clostridium_phage	5.4e-276	60.6
WP_003357721.1\|3596174_3596312_+	hypothetical protein	NA	NA	NA	NA
WP_003357936.1\|3596298_3596574_+	VRR-NUC domain-containing protein	A0A0A7RTE1	Clostridium_phage	5.4e-23	86.7
WP_003358039.1\|3597999_3598479_+	hypothetical protein	I2E8Y5	Clostridium_phage	2.7e-25	43.7
WP_003357935.1\|3599110_3599455_+	hypothetical protein	NA	NA	NA	NA
WP_003358041.1\|3599521_3600115_+\|terminase	terminase small subunit	U5PZD3	Bacillus_phage	1.4e-20	36.8
WP_003358133.1\|3600107_3601517_+\|terminase	phage terminase large subunit	A0A0A7RTS1	Clostridium_phage	3.6e-211	87.2
WP_031368140.1\|3601530_3602982_+\|portal	phage portal protein	A0A0A7S074	Clostridium_phage	4.4e-233	85.8
WP_003357989.1\|3602971_3604003_+\|head	phage head morphogenesis protein	A0A0A7RVY7	Clostridium_phage	1.7e-146	75.7
WP_003357813.1\|3604099_3604681_+	hypothetical protein	NA	NA	NA	NA
WP_003358074.1\|3604748_3605108_+	hypothetical protein	A0A2H4J4N9	uncultured_Caudovirales_phage	2.0e-49	81.5
WP_003357803.1\|3605130_3605703_+	scaffold protein	A0A0A7RTM5	Clostridium_phage	1.7e-39	54.7
WP_003357819.1\|3605725_3606793_+	hypothetical protein	A0A0A7RTH8	Clostridium_phage	2.5e-180	88.5
WP_031367423.1\|3606812_3607157_+	hypothetical protein	A0A0A7RTX9	Clostridium_phage	2.6e-43	75.4
WP_003358011.1\|3607158_3607542_+	hypothetical protein	A0A0A7S083	Clostridium_phage	3.7e-54	83.5
WP_003357746.1\|3607541_3608033_+	HK97 gp10 family phage protein	A0A0A7RTT0	Clostridium_phage	2.1e-62	75.3
WP_003357825.1\|3608034_3608466_+	hypothetical protein	A0A0A7RTI2	Clostridium_phage	5.1e-52	75.4
WP_003358030.1\|3608627_3609938_+	hypothetical protein	A0A0A7S087	Clostridium_phage	1.3e-212	85.1
WP_003358090.1\|3609941_3610406_+\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	1.1e-68	83.1
WP_003358106.1\|3610421_3610835_+	hypothetical protein	A0A0A7RTN3	Clostridium_phage	2.1e-55	77.0
WP_003357987.1\|3611089_3611851_+	SHOCT domain-containing protein	X5JB37	Clostridium_phage	2.6e-43	42.8
WP_003357961.1\|3611908_3614068_+	hypothetical protein	A0A0A7S091	Clostridium_phage	1.6e-133	48.0
WP_003358114.1\|3614067_3614745_+	LysM peptidoglycan-binding domain-containing protein	A0A0A7RVP5	Clostridium_phage	4.6e-92	75.0
WP_003358132.1\|3614756_3615731_+	hypothetical protein	A0A0A7RTZ4	Clostridium_phage	2.7e-157	84.9
WP_003357723.1\|3615733_3616078_+	DUF2577 domain-containing protein	A0A0A7RTJ2	Clostridium_phage	7.4e-38	74.6
WP_003357890.1\|3616080_3616488_+	DUF2634 domain-containing protein	A0A0A7RTH1	Clostridium_phage	1.1e-51	78.5
WP_003358010.1\|3616488_3617583_+\|plate	baseplate J/gp47 family protein	A0A0A7S096	Clostridium_phage	1.3e-160	76.1
WP_003357941.1\|3617563_3618187_+	DUF2313 domain-containing protein	A0A0A7RVP9	Clostridium_phage	2.4e-79	71.4
WP_003357943.1\|3618189_3619929_+\|tail	phage tail protein	A0A0A7RTQ0	Clostridium_phage	1.9e-60	51.1
WP_003357937.1\|3619961_3620354_+	hypothetical protein	B6SBV4	Clostridium_virus	4.5e-07	37.6
WP_003357857.1\|3620346_3620469_+	XkdX family protein	A0A0A7S0E7	Clostridium_phage	4.5e-06	57.5
WP_003394958.1\|3620792_3621989_+\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	4.7e-87	44.4
WP_003358136.1\|3622156_3622576_+\|holin	phage holin family protein	A0A0A7S099	Clostridium_phage	1.1e-43	66.2
WP_003358121.1\|3622620_3623391_+	SH3 domain-containing protein	A0A2H4J8A3	uncultured_Caudovirales_phage	2.2e-90	66.1
WP_003357838.1\|3623569_3625138_+	ATP-binding protein	NA	NA	NA	NA
WP_100067000.1\|3625226_3626090_+	DNA adenine methylase	NA	NA	NA	NA
WP_003357984.1\|3626940_3627129_+	hypothetical protein	A0A0A7RTH9	Clostridium_phage	2.9e-12	70.9
WP_003358148.1\|3627130_3627373_+	hypothetical protein	NA	NA	NA	NA
WP_003357926.1\|3627422_3627563_+	hypothetical protein	A0A0A7S0D9	Clostridium_phage	2.2e-12	77.3
WP_031367398.1\|3628701_3630216_+	DUF1538 domain-containing protein	NA	NA	NA	NA
3627822:3627882	attR	NA	NA	NA	NA
WP_003358128.1\|3630723_3633318_+	cation-transporting P-type ATPase	NA	NA	NA	NA
WP_003357983.1\|3633422_3633653_+	hypothetical protein	NA	NA	NA	NA
WP_003357743.1\|3633664_3635452_+	ComEC/Rec2 family competence protein	NA	NA	NA	NA
WP_003357804.1\|3635480_3636512_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_003358111.1\|3636546_3636813_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_003357832.1\|3637022_3637997_+	GPR endopeptidase	NA	NA	NA	NA
WP_003357912.1\|3638181_3639273_+	stage II sporulation protein P	NA	NA	NA	NA
WP_003358116.1\|3639343_3639739_+	hypothetical protein	NA	NA	NA	NA
WP_003357725.1\|3639879_3641688_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	4.2e-23	25.3
WP_003357872.1\|3641714_3642857_+	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_003357960.1\|3643057_3644089_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_003357929.1\|3644115_3644760_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_003357980.1\|3644814_3646686_+	molecular chaperone DnaK	A0A2P1EIW2	Megavirus	1.6e-142	46.7
WP_003357741.1\|3646828_3647974_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.2e-25	29.0
WP_003357816.1\|3648281_3649220_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_003358022.1\|3649317_3650076_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_003357957.1\|3650075_3651374_+\|tRNA	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB	NA	NA	NA	NA

DBSCAN-SWA_5

3729004 : 3738473

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003357997.1\|3729004_3731560_+	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	1.3e-09	32.4
WP_003357851.1\|3732235_3732715_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.1e-26	48.7
WP_003358103.1\|3732714_3733419_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	1.0e-41	42.1
WP_003385256.1\|3733510_3734959_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.2e-58	35.1
WP_003357871.1\|3735019_3736015_+	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	3.4e-67	44.0
WP_003357901.1\|3736142_3736760_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-25	40.6
WP_031367308.1\|3736973_3738473_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.1e-69	46.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP031100

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP031098

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection