CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021933	Lactiplantibacillus plantarum strain TMW 1.1478 plasmid pL11478-1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP021932	Lactiplantibacillus plantarum strain TMW 1.1478 chromosome, complete genome	1 crisprs	csa3,DinG,cas3,DEDDh	1	1	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021932_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021932_1

2621608-2621833

Orphan

Consensus_repeat	Method
ACTTGTCCAGAACCATCAGCCAACTGACTGACACCACTAGCCAACGCCCCAGTCTTAC	PILER-CR

2 spacers

csa3

The CRISPR arrays of NZ_CP021932_1

>merge|NZ_CP021932|1|2621608-2621833|PILER-CR
ACTTGTCCAGAACCATCAGCCAACTGACTGACACCACTAGCCAACGCCCCAGTCTTACCATTCAATGTTCCAAGCCCATTAGTAACTTGTCCAGAACCATCAGCCAACTGACTGACACCACTAGCCAACGCCCCAGTCTTACCATTCAACGTTCCTAGCCCATTAGTGACTTGCCCGGAACCATCAGCCAACTGACTGACACCACTGGCTAACGCCCCGGTCTTAC

>NZ_CP021932|1|1|2621608-2621833|PILER-CR
ACTTGTCCAGAACCATCAGCCAACTGACTGACACCACTAGCCAACGCCCCAGTCTTAC	CATTCAATGTTCCAAGCCCATTAGTA
ACTTGTCCAGAACCATCAGCCAACTGACTGACACCACTAGCCAACGCCCCAGTCTTAC	CATTCAACGTTCCTAGCCCATTAGTG
ACTTGCCCGGAACCATCAGCCAACTGACTGACACCACTGGCTAACGCCCCGGTCTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021932.1\|WP_015825877.1\|2626507_2627338_-\|phosphotransferase	unknown	unknown	gnl\|CDD\|270702
NZ_CP021932.1\|WP_015825875.1\|2622596_2623151_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP021932.1\|WP_061871337.1\|2613914_2615666_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|182732
NZ_CP021932.1\|WP_003644778.1\|2629103_2630726_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NZ_CP021932.1\|WP_024002907.1\|2624074_2625019_-\|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl\|CDD\|214889
NZ_CP021932.1\|WP_003642181.1\|2623248_2623578_-\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP021932.1\|WP_027821794.1\|2606201_2606762_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021932.1\|WP_060684132.1\|2609492_2610359_-\|DUF3737-family-protein	unknown	unknown	gnl\|CDD\|378875
NZ_CP021932.1\|WP_033617504.1\|2617819_2618377_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021932.1\|WP_021356578.1\|2605134_2605818_+\|noncanonical-pyrimidine-nucleotidase,-YjjG-family	unknown	unknown	gnl\|CDD\|162788
NZ_CP021932.1\|WP_060684135.1\|2615935_2617330_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP021932.1\|WP_003644847.1\|2612127_2613915_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP021932.1\|WP_011101965.1\|2625095_2625641_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP021932.1\|WP_061871338.1\|2631927_2633853_-\|DUF2207-domain-containing-protein	unknown	unknown	gnl\|CDD\|378333
NZ_CP021932.1\|WP_003642184.1\|2625903_2626431_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP021932.1\|WP_060684133.1\|2610461_2611490_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305
NZ_CP021932.1\|WP_033608924.1\|2627805_2629011_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP021932.1\|WP_114693075.1\|2631046_2631841_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319820
NZ_CP021932.1\|WP_114693074.1\|2608330_2609503_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP021932.1\|WP_027821793.1\|2607588_2608182_-\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224996

Protein	Function_ID	Function_description	E-value
NZ_CP021932.1\|WP_015825877.1\|2626507_2627338_-\|phosphotransferase	gnl\|CDD\|270702	cd05153, HomoserineK_II, Type II Homoserine Kinase. This subfamily is composed of unusual homoserine kinases, from a subset of bacteria, which have a Protein Kinase fold. These proteins do not bear any similarity to the GHMP family homoserine kinases present in most bacteria and eukaryotes. Homoserine kinase catalyzes the transfer of the gamma-phosphoryl group from ATP to L-homoserine producing L-homoserine phosphate, an intermediate in the production of the amino acids threonine, methionine, and isoleucine. The Type II homoserine kinase subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	3.51122e-07
NZ_CP021932.1\|WP_015825875.1\|2622596_2623151_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.86636e-07
NZ_CP021932.1\|WP_061871337.1\|2613914_2615666_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|182732	PRK10789, PRK10789, SmdA family multidrug ABC transporter permease/ATP-binding protein.	0
NZ_CP021932.1\|WP_003644778.1\|2629103_2630726_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP021932.1\|WP_024002907.1\|2624074_2625019_-\|DNA/RNA-non-specific-endonuclease	gnl\|CDD\|214889	smart00892, Endonuclease_NS, DNA/RNA non-specific endonuclease. A family of bacterial and eukaryotic endonucleases share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. An histidine has been shown to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion.	6.05604e-24
NZ_CP021932.1\|WP_003642181.1\|2623248_2623578_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.32613e-13
NZ_CP021932.1\|WP_060684132.1\|2609492_2610359_-\|DUF3737-family-protein	gnl\|CDD\|378875	pfam12541, DUF3737, Protein of unknown function (DUF3737). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 281 and 297 amino acids in length.	5.59866e-179
NZ_CP021932.1\|WP_021356578.1\|2605134_2605818_+\|noncanonical-pyrimidine-nucleotidase,-YjjG-family	gnl\|CDD\|162788	TIGR02254, hydrolase_haloacid_dehalogenase-like_family, noncanonical pyrimidine nucleotidase, YjjG family. This HAD superfamily includes including YjjG from E. coli and YfnB from B. subtilis. YjjG has been shown to act as a house-cleaning enzyme, cleaving nucleotides with non-canonical nucleotide bases. This family is a member of the haloacid dehalogenase (HAD) superfamily of hydrolases which are characterized by three conserved sequence motifs. By virtue of an alpha helical domain in-between the first and second conserved motif, this family is a member of subfamily IA (TIGR01549).	6.30531e-49
NZ_CP021932.1\|WP_060684135.1\|2615935_2617330_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.66222e-56
NZ_CP021932.1\|WP_003644847.1\|2612127_2613915_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.03372e-169
NZ_CP021932.1\|WP_011101965.1\|2625095_2625641_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.46296e-18
NZ_CP021932.1\|WP_061871338.1\|2631927_2633853_-\|DUF2207-domain-containing-protein	gnl\|CDD\|378333	pfam09972, DUF2207, Predicted membrane protein (DUF2207). This domain, found in various hypothetical bacterial proteins, has no known function.	5.54156e-122
NZ_CP021932.1\|WP_003642184.1\|2625903_2626431_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.41001e-30
NZ_CP021932.1\|WP_060684133.1\|2610461_2611490_-\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	2.65663e-135
NZ_CP021932.1\|WP_033608924.1\|2627805_2629011_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	6.00928e-09
NZ_CP021932.1\|WP_114693075.1\|2631046_2631841_-\|HAD-family-hydrolase	gnl\|CDD\|319820	cd07518, HAD_YbiV-Like, Escherichia coli YbiV sugar phosphatase/phosphotransferase and related proteins; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli YbiV can act as both a sugar phosphatase and as a phosphotransferase. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.82611e-48
NZ_CP021932.1\|WP_114693074.1\|2608330_2609503_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	3.30488e-145
NZ_CP021932.1\|WP_027821793.1\|2607588_2608182_-\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|224996	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only].	1.72029e-34

>NZ_CP021932.1|WP_033617504.1|2617819_2618377_+|hypothetical-protein
MNYTSQANIHKFTVSLVIILLSSILISTTITLKISANTTSSSQQAIDCIAQELADVSNSIRYDPQTGLATNLDVNALVSKYGSNNQNQLQHINEIMKYEYKRNLQFNQGKLNSIQTRSFWSCMKNQLLDMIGYQTFQALLRGGIQGLIQRKAWKAAAKLLIRYLGDGIGVGFIAAQLSWYAIRCA
>NZ_CP021932.1|WP_060684135.1|2615935_2617330_+|MFS-transporter
MSQPSTVTLKTKLAILSVGLLSFVGILVETSMNVTFPTLIKTMGVSLDTVQWLTTGYLLLTTIVMSTTAYVLKRFNPKPLFLFAALVCLLGGILCWLAPNFPILLTGRLLQAVATGISIPLMFQLIFTYVPRNQLGTYTGLASVIVSLAPALGPTYGGILTSVWSWRAIFVGIVPLLALLAILGAFNISGKALGVGDKKFDYLGAILLAITFTSLLFTFNNAGTHGWLSPNFGLWCLWSIVMIGAMVTYAIKGRRQLIDYSILKLPILRLRLFNYFGLQFINIGLSFVLPLFAQTVLGASAMTAGLMMLPGAIVGAITGPIAGRIYDKQGPTTLLTFSAIMASAALLLFWLTTDYFTVIIMAVIYALLRVGFNTGFGTAISDGSTRVPLPQKSDQNSMFSMMQQYAGSIGTSIMSAVIAGYEIHHPTVTGTIMGSKLDFLLLFVLAIAILISVLHVKRLEIGQN
>NZ_CP021932.1|WP_061871337.1|2613914_2615666_-|ATP-binding-cassette-domain-containing-protein
MSIFLKLGWYFRREWKLYLAGVLGLVLTAIIGIVPPRIIGDVVDGINQHSLTAHTLAVYLVIIGVAAVGQYLARYLWRNAIWGGAAGLERTLRERLFWHFMKMDATFYQQYRTGDLMAHATNDLTAVERVAGGGILQFADSIITGGTTLIAMMTLIDWRLTLIAVVPFPLLAVVSRYLGKKIHVAFRASQAAFSRLNNKAQESISGIKVIKALGQEKADVADFNQQIDQTIKINRHVNVLDSLFDPAITMIIALSYGATIILGGLYVTHGVITIGNLVSFVTYLGMMVWPMFAVGMLFNTMERGNASYDRVMELLNQQSAIIDAKRGIEQRPHGDIQYQIKQFNYPNDAGTSLSNVDFTLKAGQTLGIVGRVGAGKSTIMKLILREFDQYDGHITYGGHDIKQYALDSYLPALGYVPQDSFLFSNTIRENIRFADPTVSQAVVEAVAAKSDLSGQIASMPAGYDTQVGEEGISLSGGQRQRLAIARALLINPELLILDDALSAVDAETEAEILANLKAERADKTTIIAAHRLSSVMNADEIIVLDAGHVVERGTHAQLMTQHGWYQKMFTRQQLETKVEGAVQ
>NZ_CP021932.1|WP_003644847.1|2612127_2613915_-|ABC-transporter-ATP-binding-protein
MAARQSVWARSMPVKEQLTVIRRLLPYAKPFKWFFIAAIVFSGLISVVNIYLPRVLQTFIDHYLKTGHATVPVMWYFAGLYFFGMVVRALMQFVQNFSSTMGAEYMLENVRRQMFAKLHRMGMRYFDQVPGGSILSRLTNDTMSFSNFWALFNTLFTAFFAVISSFVAMYLTDAQIALWLLVFMPFLAVTIWYYQRYSSRVYRRMRERLSELNTKLSEAITGISVIQQFRQEHRINGEFDHTNDAYFKTRQAMIRTNSLLLSPLIDLFYALGTVMVLGIFGVRGLNGYVAAGVVYAFITYLNNFYNPMTSMMDNLSDFQDGVVAGSRVLRVMDDPTIAPAQHADPTAKITRGKIEFRHVTFAYDGQHPVLKDVSFVAEPGQTVALVGQTGSGKTSTINVLMRFYEFQSGEVLIDDRDIREYPAEELRQKMGLVLQEPFMFYGDINSNIRMFNDQISDEQVQAAARFVKADDFINDLPENYQSRVIERGASYSSGQRQLISFARTIVTDPKILILDEATANVDTETEEMIQTGLDRIQENRTTIAIAHRLSTIQNADLILVLNQGQIVERGSNDELLQQHGYYYDMIQLQNSAHVD
>NZ_CP021932.1|WP_060684133.1|2610461_2611490_-|aldo/keto-reductase
MQYRQLGTSDLKVSSIALGCMGFGAGTGTALNQRSWAVGQTQANQVLDRAISLGINFFDTAPVYQAGASERVLGQGLKKFQRDQLVLATKFTNRTTQEIENHVSGREHVLRSLDQSLQNLQTDYVDLYIYHIWDWLTPMAEIMAGLNEAVQAGKVRYIGISNAYSWQIAQINALAVRYGYPQFVSIQSHYNLVYREDERELFSYAHENDLATTPYSPLASGRLAHPFGTQTTRRQQDTFADTKYQATSEMDKPIIDRVEELAHQHHVSMAAINLAWLQQRVTAPIIGATKPHHLDAVAEAAGLALTASEIQYLETPYRPHDLEGVMALNRSRTNNWNQYSGQ
>NZ_CP021932.1|WP_060684132.1|2609492_2610359_-|DUF3737-family-protein
MKTITQQYLTGERALFKAHDLEIDNTTFADGESPLKESRNVTLKQPIFKWKYPLWYSQHVTVDQGLFETMSRSGIWYTKDITITNSTLQAPKLFRRASQVKLAHVHFSDAEETLWNCQDITLNDVQAAGDYFGMNSQNIRIDGFNLFGNYAFDGAKNVEIHHATLMTKDALWNCENVTVYDSQIIGEYLGWNSKNIRFVNCTIESDQGLCYMDNVKLENCTLLNTDLAFEYCRNIDADVVSTIDSVKNPLSGRIHAQAIGEIIMDDPEVDPHQTLISVDHESRAPHAV
>NZ_CP021932.1|WP_114693074.1|2608330_2609503_-|pyridoxal-phosphate-dependent-aminotransferase
MPFDFETVLNRRHTNAVKWDVADNELPMWVADMDFETAPVIKQALIKRAQFGVFGYEEVPTAYYEAVADWWATEHNFRPQIEWLMFCTGVVPAISSIVRKMTAAGDNVLVQAPVYNIFYHSIENNGRHTLSSDLVAHDAAYTIDWDDLTTKLADPLTTMMILCNPQNPIGIVWSRATLQRLGELCLKYHVLVVADEIHCDLTLNGHTYTPFSSLTAPVAHNSISCISPSKTFNVAALHAATLIIPDAHVRALVSRGINNDELAEPNSFAIPASIAAYTEGHDWVAALRTKLAANQRQVQTYLTAELPQVKLVEAQATYLLWLDVRQVTTDSAALAAFIRQRTGLFLSAGDVYRGDGNRFLRLNVACPTTTLTNGLARLKAGITAYQQIQA
>NZ_CP021932.1|WP_027821793.1|2607588_2608182_-|NAD(P)-binding-domain-containing-protein
MEIGIIGAGTVGTVLAKTFARGDHQIKLSRHSGAASLATRRAEFAANVAFVEVAEALQQPLVILAVPFEQAPAVLAQVADYKQRIVVDVTNQFTADFKKIKTAPLTGSEVIARAANNARVIKAFNTIPPEFMDGHVDGPGKRVLFYAGDDVAAKKEFAALVRPLNFRPVNLGKLRHGGSVMQVGGGLGNTHFVQIEE
>NZ_CP021932.1|WP_027821794.1|2606201_2606762_-|hypothetical-protein
MSSYSNELLMLIFQSTLFKQVIILFAYGCLYYLVTHFIDKKIQHKKNFLLKLGLVKLKKRNKTRWEKIRLIMQLFLLASIPVLVFSELVLNTDYQYMLLVSSIMKCVGFISFVIAFVDSLGPIKEMQQLIAGAQSSDTLDSDKKALAVTSFKKIRWMLILYQVLKVPLLVIFLSLSVDYRRDGFFS
>NZ_CP021932.1|WP_021356578.1|2605134_2605818_+|noncanonical-pyrimidine-nucleotidase,-YjjG-family
MQYAIFDLDNTILDFDRAEAANLAAVFQHHGVTDIRRAENEYQAYNETVWQQIEQGADRDSLLDQRFQVFLGTLGITVDGPAVQQEYDQLLAHSYQVIPGAHELLRTLTNAGLTLLVGTNGIKHTQLSRLAGAHMTPYFDHIFISESIGYAKPNPHFFNAIHDQYPDMNATNTVMIGDSLRSDIAGAATVQLPSIWYNPQHAHNDTTIAPTYTVDNFKQLQKLLLTA
>NZ_CP021932.1|WP_015825875.1|2622596_2623151_-|TetR/AcrR-family-transcriptional-regulator
MVISIRTELDLQRAMYQLLEQRSISQITVEQICKQAFIHRSSFYRYYTDKFDLLRQMVMHTLDELLAAERTDTVGSAIMSTFIGAHTQVLRHLLVTNNEGDNTRSQQVINDCFVTVAETGADDRVFAMIRQSQHPDLTAYLVSGVVTSIVQWLNNGHRDGQAASTQAMIQGTLATVFSLEQHTV
>NZ_CP021932.1|WP_003642181.1|2623248_2623578_-|winged-helix-turn-helix-transcriptional-regulator
MVSSEEALQEFRETIPIFEVLADERRQQIMIELSQHAQGMTVGELTERMHISQPAVSHQLKTLKERHFVAVEHQGTRNYYRVTFDAPLTQVEHLIHTLKADLELKPYLH
>NZ_CP021932.1|WP_024002907.1|2624074_2625019_-|DNA/RNA-non-specific-endonuclease
MVKLMRRVGIAGLLSLSLLLGGCSLLTSGTDTTSSTTSQQSESSRNQTTSATGNTQQTYKQLAKMTYQSGSAAAIKVNSGKSTLAASQWKNSKIDYGNLDSLNRTTTDTAYLSKANLGRSEGRTAQTWSPTGWHNQPITVNGKRVYPQNRGHLIAYTLSFNLTSNGQYRAGEDGSLDNPKNLATQTAYSNQKTMQIYEDQVRTALEQGKKVIYRVTTVFRGNELMPRGYWSQAVSTDGSVNFNVYIWNVEPGVSFDYATGRGKADSTMQVAGADKVSSSQNTSASRSSQSTTTSKQVERELVKYGYKYVKKALN
>NZ_CP021932.1|WP_011101965.1|2625095_2625641_-|GNAT-family-N-acetyltransferase
MTATITIRPLQRAELTMLWQLGFSDPNAEWTRWNGPYFHDQLPTQTDFETIIGPRDWLIRPRNWVITRDGVIVGSVNWHFVDGSLKRWLEVGIIIYNQEHWGEHIGRTALTKWLTHLFQEETTLPHIGLTTWSGNMRMMQLAEAVGLKQEAWIPQVRYWQGQYYDSVKYGILRNDWQVQKD
>NZ_CP021932.1|WP_003642184.1|2625903_2626431_-|GNAT-family-N-acetyltransferase
MTQFETERLILRPMTAADHDALADMIFDPQVVAYLRYRRVQSPAAFEQLFTTHFLADTTTVFGIERRRDHQLIGFYEFHGSGATGELTYALSPAAWGHGYVAEAGNCLMHYGFETLNYETIEAHYASANPNSGRVMAKMGMQAAGELHTFTSDKGEVIHVMRYLLTKATWRQLSA
>NZ_CP021932.1|WP_015825877.1|2626507_2627338_-|phosphotransferase
MRTLHKTLTRLLQADLIPIAHVSFNEMYTGYSRRYDTVVFVKVFSPNHERKFRTEQQVTAQLTDRVLASFQLASREWVLVLRDWQLTPVPTTLTPALVYQMGQVVSRFHHAIQLPTTADLMPVLDFDGMAARVERLKTSPHYDALVSLLPYFLDHRTMIITALAPQPVMTLHGDMGTRNFRYHHGQLVLIDFERARHGYALEDCLKFFFEDLQQSATLIQAFWAGYGTDLQIPPLVTQWLLLQCSTGIFTYVNQITDPRFEAVGTAMLAQVTLPNH
>NZ_CP021932.1|WP_033608924.1|2627805_2629011_-|CPBP-family-intramembrane-metalloprotease
MTPETEQLLRRWYMGQLIVLFGAAFIQLFTFDGGVFFPVGGMQLLIWGLLAWWPAAEEDQAQWRRLRHVNYYVQTVLQFTLLPILLANLVAWLSQLSWLDEQGLIAVGMAYLMVAFVPVAVVVTKPIESVIGRIAVLITAIFSGVVSAQQTFLVLPNLQAPSVFEMVSDTGILGALGFVIAVGVLLRGWGLTGPSWRFNRQAQTSLVVGLIVVGTAFSLWNAFSAGGSWATTFTHWDFQLRSATWKMFLSGLEPGIAEEWLYRFAVLTLLLQAFRHRRHQLDLAVWLSGGLFGMWHITNVFAGQPLSATVEQIIFAATLGWFLASTYLYSGSILLPMVIHAAIDILSMMASGSQTMVKPDAFEWQTIGATVIIFVGITIYFLTGSRRQVIQAHVNQRLSVQ
>NZ_CP021932.1|WP_003644778.1|2629103_2630726_-|ATP-binding-cassette-domain-containing-protein
MLTVNNVSMQFSTRKLYEDVNLKFTPGNCYGVIGANGAGKSTFLKILEGKLQPTTGTVSMGPNERMSSLNQNHFAFEDEEVLATVIRGHEKLYEIMTEKDALYAKPDFSDEDGIRAAELEGEFAEMDGWNAESEADQLLQNLGIDESMQHLKMSELTEPQKVKVLLGQALFGSPDVLLLDEPTNGLDVQSISWLEDFLAGYEKTVIVVSHDRHFLNQVCTHMCDVDFGKITLFVGNYDFWMESSQLAAKLQANANAKKADQIKELQEFVARFSANASKSKQATSRKKQLEKITLDDIKPSSRKYPFIKFTPDREIGNDLVKVENVSKSIEGVKILDNISFTLRPNEKTALISRNDLATTTLMQIIAGSMAPDSGTVTWGQTTSRTYLPKDINEEYAGSELPIIDWLRQFASKEESDNTFLRGFLGKMLFSGSDVERPVNVLSGGEKVRGMLSKMMLSRANVLLLDDPTNHLDLESITALNDSLIDFKGAIVFTSHDHEFIQTIADHIVEVSAKGVVDRGDTTYDEYLAHEATQGRVQDLY
>NZ_CP021932.1|WP_114693075.1|2631046_2631841_-|HAD-family-hydrolase
MTIKLIATDMDGTFLNDHGDYDQERFANDYAALQRRGIQFVIASGHQAAELVTTFSAYPEMWLIGGNGAELWQREAGLKAATFSPQATQQVLAALAPYPELQVALCGTQTVHVLAHANPQFVANMRDYYYQLETCADLTTVTDPVVKFDVICPAAMTDQLVYELTPKLAGIAVPASGGQGSMDLIQPGMHKGRALKQLGEQLGILPDEMLVFGDGTNDLEMFHYATHAVAMQNAPENVQANATAVTGTNVDNGVLDYIEQHILS
>NZ_CP021932.1|WP_061871338.1|2631927_2633853_-|DUF2207-domain-containing-protein
MPKKALAVSRAPRLGEYDKLGLTIIGGGDGEMSKKRRLSWLSVLGLLAGFCWWFSLAMRAAADYDIDQYQVNVAIQRDGSANVTQAMTYQFDDDYHGVFNVQDLKGIQGAQLEGVTTQLNGGTTVTAAPSETGANNTYQLTQNADRMRVKLYRQVQEDDKLRVVYRYRLKGVVTNYADTAELNWKVIGSGWDVPLNNVKIVIQLPAKNVSALQAWTHGPLSGQTKVERAAGRVTMTLGHNPANQFVESHLLFPTTVTATNTRTNTAKRKATVQKQEAKLAQEANEKRRRNRLLRRVIFGTAVAGWLLVMIGYLWWLARHPAKPHQQPIPINHSFDVPPVTPAVAESLWAQRSPNTDALTAEILRAAANHEITIETVAGHRKPDVRLTQLKPVTNSFLAHCFDKIAVDGQFMLTDLKKYGKRDKAGRLGKWFSRWQTEVDQDVAVYQDETNYRLRNQWLMAAVVVSVMGMIATGAGLLVSPKVVTLMVIPAIVAAVAFWIGWIIQRRRIAINTDAGLELRNQINGLRRMLKDIGHFNTAQVGDLILWEQILPYAAAFGLANQVTKQLTIDFGTEALATGMLVYYPLFYANGGLDFDLSGAINDSFSGALDASGSASSASGGSGGFSGGSSGGFGGGSGGGAF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP021932_1	1.1\|2621666\|26\|NZ_CP021932\|PILER-CR	2621666-2621691	26	NZ_CP021932.1	2621582-2621607	0	1.0

1. spacer 1.1|2621666|26|NZ_CP021932|PILER-CR matches to position: 2621582-2621607, mismatch: 0, identity: 1.0

cattcaatgttccaagcccattagta	CRISPR spacer
cattcaatgttccaagcccattagta	Protospacer
**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021932_1	1.1\|2621666\|26\|NZ_CP021932\|PILER-CR	2621666-2621691	26	AP014283	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C59, * SEQUENCING IN PROGRESS *	15532-15557	4	0.846

1. spacer 1.1|2621666|26|NZ_CP021932|PILER-CR matches to AP014283 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C59, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 4, identity: 0.846

cattcaatgttccaagcccattagta	CRISPR spacer
cattaaatgttccatgcccattaaaa	Protospacer
**** ********* ********. *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

322306 : 408359

Bacillus_virus(20.0%)

protease,transposase,bacteriocin,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643762.1\|322306_322870_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_011100974.1\|323063_323732_+	ribose 5-phosphate isomerase A	NA	NA	NA	NA
WP_003641930.1\|323881_325387_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_003643763.1\|325651_326020_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_003641932.1\|326132_326642_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_024521227.1\|326672_327869_-	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_003646440.1\|327978_328449_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003641935.1\|328467_328923_+	hypothetical protein	NA	NA	NA	NA
WP_013355176.1\|329026_329599_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_013355177.1\|329764_330685_-	ribonucleoside hydrolase RihC	NA	NA	NA	NA
WP_021356913.1\|330821_331733_+	oxidoreductase	NA	NA	NA	NA
WP_024521230.1\|332584_333031_-	ribonuclease H	NA	NA	NA	NA
WP_003643770.1\|333268_334795_+	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_015825109.1\|334795_335767_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.7
WP_021356773.1\|335844_337176_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003643773.1\|337641_339159_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_003643774.1\|339173_341003_+	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_114692872.1\|341017_341740_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.5e-29	31.5
WP_047672635.1\|342326_346022_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_047672638.1\|347930_348239_+	hypothetical protein	NA	NA	NA	NA
WP_021356072.1\|348655_348934_+	hypothetical protein	NA	NA	NA	NA
WP_074161480.1\|348997_349114_+	hypothetical protein	NA	NA	NA	NA
WP_021356071.1\|349237_350155_+	hypothetical protein	NA	NA	NA	NA
WP_016526893.1\|350161_350335_+	hypothetical protein	NA	NA	NA	NA
WP_016511577.1\|350879_351422_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_011100988.1\|351436_351700_+	hypothetical protein	NA	NA	NA	NA
WP_003643788.1\|351816_352020_+	hypothetical protein	NA	NA	NA	NA
WP_003646452.1\|352144_352384_+	hypothetical protein	NA	NA	NA	NA
WP_047672646.1\|352401_352788_+	hypothetical protein	NA	NA	NA	NA
WP_112297220.1\|353630_353777_+	glycohydrolase toxin TNT-related protein	NA	NA	NA	NA
WP_061871721.1\|353853_354261_+	immunity 63 family protein	NA	NA	NA	NA
WP_011100991.1\|355531_355810_+	hypothetical protein	NA	NA	NA	NA
WP_015379760.1\|356136_356754_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_021356659.1\|356757_357912_-	MFS transporter	NA	NA	NA	NA
WP_047672651.1\|357915_358707_-	HAD family hydrolase	NA	NA	NA	NA
WP_003641965.1\|358777_359650_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_003641966.1\|359809_360625_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_021356661.1\|361150_362527_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_011100995.1\|362571_363756_+	cation:proton antiporter	NA	NA	NA	NA
WP_003641969.1\|364140_364344_+	hypothetical protein	NA	NA	NA	NA
WP_013355194.1\|364742_366005_+\|transposase	ISL3-like element ISP1 family transposase	NA	NA	NA	NA
WP_003641971.1\|366196_366865_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_003641972.1\|366861_367035_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnK	NA	NA	NA	NA
WP_003641973.1\|367065_367233_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnJ	NA	NA	NA	NA
WP_003641974.1\|368094_368295_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_003641975.1\|368422_368590_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_061871501.1\|368707_369907_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_003641977.1\|369937_370684_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003641979.1\|371561_371708_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_021356664.1\|371898_373227_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_021356665.1\|373227_373971_+	response regulator transcription factor	NA	NA	NA	NA
WP_061871499.1\|374089_374833_+	response regulator transcription factor	NA	NA	NA	NA
WP_021356666.1\|375126_375900_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021356667.1\|375998_376157_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA
WP_003641985.1\|376181_376352_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnE	NA	NA	NA	NA
WP_114692874.1\|376618_378769_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	1.4e-44	27.7
WP_061871498.1\|378784_380161_+	HlyD family secretion protein	NA	NA	NA	NA
WP_003641990.1\|381007_381676_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003641991.1\|381762_382443_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_107787271.1\|382536_383223_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003641993.1\|383360_383564_+	hypothetical protein	NA	NA	NA	NA
WP_003641994.1\|383658_385968_-	ATP-binding domain-containing protein	NA	NA	NA	NA
WP_003643814.1\|386226_387003_+	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_003643815.1\|387441_388458_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_003641997.1\|388865_389576_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003641998.1\|389648_391010_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_003641999.1\|391016_391205_+	hypothetical protein	NA	NA	NA	NA
WP_003642000.1\|391194_391617_+	DUF3284 domain-containing protein	NA	NA	NA	NA
WP_003643816.1\|391839_393195_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_003642002.1\|393212_394649_+	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	9.7e-31	25.5
WP_003642003.1\|394769_395666_+	ROK family protein	NA	NA	NA	NA
WP_003642004.1\|395815_396562_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_003643818.1\|396674_397688_+\|tRNA	tRNA-dihydrouridine synthase family protein	NA	NA	NA	NA
WP_003642006.1\|398141_399275_+	hypothetical protein	NA	NA	NA	NA
WP_003643820.1\|399279_400074_+	hypothetical protein	NA	NA	NA	NA
WP_003642008.1\|400242_401160_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_003642009.1\|401205_402480_+	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
WP_114692875.1\|402472_403432_+	IpaB/EvcA family protein	NA	NA	NA	NA
WP_003642011.1\|403453_404158_+	NAD-dependent protein deacylase	NA	NA	NA	NA
WP_003642012.1\|404157_405000_+	DUF72 domain-containing protein	NA	NA	NA	NA
WP_003646492.1\|405596_405986_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_003643823.1\|406307_408359_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	2.7e-90	35.8

DBSCAN-SWA_2

485460 : 593463

106

Lactobacillus_phage(76.67%)

protease,tail,portal,integrase,tRNA,capsid,terminase,lysis,head

attL 473797:473814|attR 556396:556413

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
473797:473814	attL	NA	NA	NA	NA
WP_114692878.1\|485460_486807_+\|tRNA	tRNA lysidine(34) synthetase TilS	A0A0N7G7K4	Chrysochromulina_ericina_virus	2.0e-09	23.8
WP_003642086.1\|486826_487369_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	1.5e-08	26.0
WP_003643854.1\|487448_489686_+\|protease	ATP-dependent zinc metalloprotease FtsH	G8DDJ2	Micromonas_pusilla_virus	6.0e-104	47.8
WP_003642088.1\|489834_490722_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_003642089.1\|490721_491729_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_003642090.1\|491832_493332_+\|tRNA	lysine--tRNA ligase	A0A2K9L3L6	Tupanvirus	1.6e-89	37.5
WP_003643855.1\|499879_501352_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.1e-68	34.3
WP_003640888.1\|501406_502249_+	metallophosphoesterase	NA	NA	NA	NA
WP_114692879.1\|503447_503972_+	cupin domain-containing protein	NA	NA	NA	NA
WP_003640891.1\|504002_504338_+	cupin domain-containing protein	NA	NA	NA	NA
WP_013355212.1\|504372_505215_+	metallophosphoesterase	NA	NA	NA	NA
WP_003640893.1\|505373_506480_-	anion permease	NA	NA	NA	NA
WP_003640894.1\|506672_507494_-	nicotinamide mononucleotide transporter	A0A2K9VCL6	Lactobacillus_phage	3.3e-52	42.2
WP_114692880.1\|507854_508646_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.6e-30	36.1
WP_003644997.1\|508724_509861_+	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_003640897.1\|509884_510586_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003643865.1\|510755_511493_-	WecB/TagA/CpsF family glycosyltransferase	NA	NA	NA	NA
WP_003640899.1\|511649_513128_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	2.5e-106	44.1
WP_024002267.1\|513127_513955_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	6.5e-72	54.0
WP_114693121.1\|514410_517065_+	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	6.8e-70	28.9
WP_003644994.1\|517119_517554_+	hypothetical protein	NA	NA	NA	NA
WP_053566457.1\|517847_520019_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_024002264.1\|520018_520465_+	SprT family protein	NA	NA	NA	NA
WP_003640905.1\|520530_521817_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_003640906.1\|521825_522701_+	homoserine kinase	NA	NA	NA	NA
WP_061871550.1\|522991_524149_-\|integrase	site-specific integrase	A0A2P0ZL94	Lactobacillus_phage	2.5e-218	98.7
WP_061871549.1\|524436_525345_-	Abi family protein	NA	NA	NA	NA
WP_061871548.1\|525491_526445_-	DUF4062 domain-containing protein	NA	NA	NA	NA
WP_061871547.1\|526620_527244_-	hypothetical protein	NA	NA	NA	NA
WP_003643876.1\|527336_527768_-	hypothetical protein	A0A2P0ZLA0	Lactobacillus_phage	7.6e-80	100.0
WP_054397034.1\|527777_528155_-	helix-turn-helix transcriptional regulator	A0A2P0ZLA1	Lactobacillus_phage	1.5e-44	68.5
WP_003643878.1\|528467_528677_+	hypothetical protein	A0A2P0ZL97	Lactobacillus_phage	7.0e-31	100.0
WP_054397032.1\|528680_528884_+	hypothetical protein	A0A2P0ZLA4	Lactobacillus_phage	4.0e-31	100.0
WP_021357721.1\|528883_529156_+	hypothetical protein	A0A2P0ZLA9	Lactobacillus_phage	1.2e-43	100.0
WP_061871546.1\|529294_529744_+	hypothetical protein	A0A2P0ZLA2	Lactobacillus_phage	2.1e-77	98.7
WP_061871545.1\|529899_530085_+	hypothetical protein	A0A2P0ZLA3	Lactobacillus_phage	1.7e-28	93.4
WP_162861273.1\|530056_530227_+	hypothetical protein	A0A2P0ZLA6	Lactobacillus_phage	1.5e-23	91.1
WP_114692881.1\|530329_530809_+	siphovirus Gp157 family protein	A0A2P0ZLB3	Lactobacillus_phage	1.1e-79	95.0
WP_114692882.1\|530808_532185_+	DEAD/DEAH box helicase	A0A2P0ZLA5	Lactobacillus_phage	3.9e-231	95.1
WP_061871542.1\|532181_532403_+	helix-turn-helix transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	5.7e-07	40.3
WP_114692883.1\|532380_533097_+	AAA family ATPase	A0A2P0ZLB2	Lactobacillus_phage	7.1e-115	99.5
WP_061871540.1\|533099_533723_+	hypothetical protein	A0A2P0ZLB9	Lactobacillus_phage	3.5e-102	97.9
WP_114692884.1\|533793_534588_+	bifunctional DNA primase/polymerase	A0A2P0ZLB0	Lactobacillus_phage	2.8e-144	96.6
WP_061871538.1\|534584_535859_+	helicase	A0A2P0ZLC4	Lactobacillus_phage	6.0e-242	98.6
WP_061871537.1\|536116_536449_+	VRR-NUC domain-containing protein	A0A2P0ZLB6	Lactobacillus_phage	1.1e-57	95.5
WP_162861274.1\|536468_536642_+	hypothetical protein	NA	NA	NA	NA
WP_187331147.1\|536644_536947_+	hypothetical protein	NA	NA	NA	NA
WP_061871536.1\|536939_537287_+	hypothetical protein	A0A1I9KKG9	Lactobacillus_phage	2.1e-08	32.5
WP_061871535.1\|537417_537729_+	hypothetical protein	A0A2P0ZLD0	Lactobacillus_phage	1.5e-50	98.1
WP_061871534.1\|537740_538172_+	hypothetical protein	A0A2P0ZLC0	Lactobacillus_phage	4.6e-69	96.3
WP_061871533.1\|538506_539376_+	DNA adenine methylase	A0A1S5PRR3	Streptococcus_phage	1.1e-80	51.4
WP_114692885.1\|539391_540663_+	hypothetical protein	NA	NA	NA	NA
WP_061871531.1\|540829_541045_+	hypothetical protein	A0A2P0ZLC2	Lactobacillus_phage	5.1e-29	88.7
WP_114692886.1\|541028_541367_+	HNH endonuclease	A0A2P0ZLC6	Lactobacillus_phage	6.8e-60	93.8
WP_061871530.1\|541366_541609_+	hypothetical protein	A0A2P0ZLD3	Lactobacillus_phage	1.7e-33	86.2
WP_054396974.1\|541626_541869_+	hypothetical protein	A0A2P0ZLD2	Lactobacillus_phage	6.8e-38	95.0
WP_063845558.1\|541976_542264_+\|terminase	P27 family phage terminase small subunit	A0A2P0ZLC8	Lactobacillus_phage	2.0e-28	68.4
WP_114692887.1\|542260_543940_+\|terminase	terminase large subunit	A0A2P0ZLE5	Lactobacillus_phage	7.4e-232	70.0
WP_114692888.1\|543958_545101_+\|portal	phage portal protein	A0A2P0ZLC9	Lactobacillus_phage	9.6e-207	94.5
WP_114692889.1\|545087_545813_+\|protease	Clp protease ClpP	A0A2P0ZLE3	Lactobacillus_phage	1.1e-107	82.4
WP_114692890.1\|545833_547012_+\|capsid	phage major capsid protein	A0A2P0ZLD6	Lactobacillus_phage	8.6e-219	99.5
WP_114692891.1\|547150_547456_+\|head,tail	phage gp6-like head-tail connector protein	A0A2P0ZLD5	Lactobacillus_phage	8.3e-41	85.1
WP_114692892.1\|547436_547826_+	hypothetical protein	A0A2P0ZLD1	Lactobacillus_phage	7.1e-69	97.7
WP_015380187.1\|547822_548230_+	HK97 gp10 family phage protein	A0A2P0ZLD7	Lactobacillus_phage	2.0e-66	94.1
WP_114692893.1\|548226_548649_+	hypothetical protein	A0A2P0ZLE4	Lactobacillus_phage	9.7e-72	97.9
WP_054396956.1\|548663_549269_+\|tail	phage tail protein	A0A2P0ZLF5	Lactobacillus_phage	3.7e-109	99.5
WP_076631449.1\|549243_549516_+	Ig-like domain-containing protein	A0A2P0ZLD8	Lactobacillus_phage	4.2e-36	100.0
WP_114692894.1\|549587_549902_+	hypothetical protein	A0A2P0ZLF3	Lactobacillus_phage	7.2e-48	89.4
WP_114692895.1\|549925_550147_+\|tail	phage tail tape measure protein	A0A2P0ZLD9	Lactobacillus_phage	1.1e-31	97.3
WP_114692896.1\|550165_554710_+\|tail	phage tail tape measure protein	A0A2P0ZLF1	Lactobacillus_phage	0.0e+00	97.8
WP_114692897.1\|554713_555535_+\|tail	phage tail protein	A0A2P0ZLE2	Lactobacillus_phage	5.7e-153	99.6
WP_114692898.1\|555554_559463_+	hypothetical protein	A0A2P0ZLE1	Lactobacillus_phage	0.0e+00	73.1
556396:556413	attR	NA	NA	NA	NA
WP_114693122.1\|559488_559971_+	DUF1617 family protein	A0A2P0ZLE0	Lactobacillus_phage	1.4e-79	98.8
WP_003643917.1\|559972_560407_+	hypothetical protein	A0A2P0ZLE9	Lactobacillus_phage	1.2e-72	100.0
WP_114692899.1\|560423_560807_+	hypothetical protein	A0A2P0ZLF7	Lactobacillus_phage	3.5e-68	98.4
WP_114692900.1\|560809_561004_+	hypothetical protein	A0A2P0ZLG4	Lactobacillus_phage	2.6e-24	98.4
WP_054396940.1\|561003_561288_+\|lysis	lysis protein	A0A2P0ZLE8	Lactobacillus_phage	3.1e-42	98.9
WP_114692901.1\|561287_562220_+	lysin	A0A2P0ZLG2	Lactobacillus_phage	5.1e-174	94.5
WP_033617401.1\|562869_563379_-	hypothetical protein	NA	NA	NA	NA
WP_033617399.1\|563760_563970_-	hypothetical protein	NA	NA	NA	NA
WP_033617398.1\|564292_565147_+	C39 family peptidase	NA	NA	NA	NA
WP_003640908.1\|565438_566413_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_003640909.1\|566448_567255_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_003640910.1\|567273_568206_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_003640911.1\|568334_568721_+	DUF956 family protein	NA	NA	NA	NA
WP_021356507.1\|569026_571876_+	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
WP_003640913.1\|571946_572366_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_114692902.1\|572362_572881_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_003640915.1\|573044_574016_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_003640916.1\|574026_574428_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_015379847.1\|574430_575753_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_015379848.1\|575749_576553_+	acetyl-CoA carboxylase carboxyltransferase subunit beta	NA	NA	NA	NA
WP_003640919.1\|576545_577319_+	hypothetical protein	NA	NA	NA	NA
WP_114692903.1\|577386_578580_-	LCP family protein	NA	NA	NA	NA
WP_003643925.1\|578889_579852_+	AEC family transporter	NA	NA	NA	NA
WP_003643926.1\|580284_581310_+	EamA family transporter	NA	NA	NA	NA
WP_003644979.1\|581459_582137_+	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_003640924.1\|582556_583249_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003643927.1\|583438_584770_-	C1 family peptidase	R4TV59	Phaeocystis_globosa_virus	5.4e-68	33.3
WP_003640926.1\|584845_585529_-	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_003640927.1\|585537_585834_-	N-acetyltransferase	NA	NA	NA	NA
WP_003640928.1\|585972_586509_+	dUTP diphosphatase	J9PV85	Bacillus_phage	2.4e-35	45.8
WP_003643928.1\|587386_588766_+	DNA repair protein RadA	NA	NA	NA	NA
WP_003640931.1\|588781_589957_+	PIN/TRAM domain-containing protein	NA	NA	NA	NA
WP_003640932.1\|590282_591773_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_003643930.1\|592050_593463_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	4.7e-46	30.2

DBSCAN-SWA_3

611910 : 620534

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643940.1\|611910_613608_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	3.9e-55	37.0
WP_003640956.1\|613629_613938_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_003637790.1\|613953_614553_+	recombination protein RecR	NA	NA	NA	NA
WP_003640957.1\|614567_614819_+	YaaL family protein	NA	NA	NA	NA
WP_003643941.1\|615216_615882_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.4e-53	52.7
WP_003640965.1\|615878_616208_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_003640966.1\|616224_617244_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-32	33.5
WP_003640967.1\|617268_617616_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.4e-12	33.3
WP_003643942.1\|617714_618611_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	9.9e-82	55.7
WP_003640969.1\|618614_619400_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_003643943.1\|619538_620534_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	5.9e-51	38.2

DBSCAN-SWA_4

1056442 : 1063769

Escherichia_phage(50.0%)

integrase

attL 1060322:1060335|attR 1068940:1068953

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063207315.1\|1056442_1057435_+	hypothetical protein	A0A0N7KVX0	Yellowstone_lake_phycodnavirus	2.7e-08	39.8
WP_063207312.1\|1057434_1058280_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_063207309.1\|1058296_1059715_+	polysaccharide biosynthesis C-terminal domain-containing protein	NA	NA	NA	NA
WP_114692928.1\|1059754_1060624_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	9.2e-101	60.8
1060322:1060335	attL	NA	NA	NA	NA
WP_003644155.1\|1060627_1061209_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.3e-38	45.1
WP_114692929.1\|1061218_1062247_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.1e-68	42.4
WP_024002617.1\|1062316_1063159_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.5e-34	37.2
WP_114692930.1\|1063190_1063769_-\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	9.3e-33	42.5
1068940:1068953	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1068372 : 1074555

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643247.1\|1068372_1069242_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	1.3e-99	60.5
WP_003644155.1\|1069245_1069827_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.3e-38	45.1
WP_003643249.1\|1069836_1070865_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	4.9e-69	42.1
WP_114692933.1\|1070935_1071802_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.3e-33	36.4
WP_003643251.1\|1071815_1072031_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_003643252.1\|1072087_1073035_+	glycosyltransferase	A0A2L1GG98	Phaseolus_vulgaris_alphaendornavirus	1.1e-09	33.3
WP_114692934.1\|1073037_1073733_+	acyltransferase	NA	NA	NA	NA
WP_114692935.1\|1073751_1074555_+	LicD family protein	A0A1V0SAS8	Catovirus	1.2e-06	40.7

DBSCAN-SWA_6

1504340 : 1543444

Lactobacillus_phage(37.5%)

tail,portal,integrase,plate,capsid,terminase,head

attL 1504303:1504317|attR 1551469:1551483

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1504303:1504317	attL	NA	NA	NA	NA
WP_114692973.1\|1504340_1505561_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	2.7e-82	41.1
WP_022638129.1\|1505853_1506135_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_061871434.1\|1506538_1507216_-	DUF3862 domain-containing protein	V9QKI2	Oenococcus_phage	8.4e-09	44.3
WP_061871432.1\|1507587_1508379_-	hypothetical protein	NA	NA	NA	NA
WP_003644968.1\|1508401_1508815_-	ImmA/IrrE family metallo-endopeptidase	A0A0M4RD70	Bacillus_phage	3.4e-05	31.3
WP_011101082.1\|1508826_1509189_-	helix-turn-helix domain-containing protein	A0A0U4KKM4	Exiguobacterium_phage	2.6e-09	32.0
WP_061871431.1\|1509361_1509592_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_141654589.1\|1509868_1510117_-	hypothetical protein	NA	NA	NA	NA
WP_061871430.1\|1510185_1510797_-	hypothetical protein	NA	NA	NA	NA
WP_080453561.1\|1510793_1511030_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_033609665.1\|1511164_1511371_+	helix-turn-helix transcriptional regulator	A0A142F1D1	Bacillus_phage	8.5e-05	51.0
WP_061871429.1\|1511370_1511667_+	hypothetical protein	NA	NA	NA	NA
WP_061871428.1\|1511691_1511874_+	hypothetical protein	NA	NA	NA	NA
WP_061871427.1\|1511938_1512487_+	hypothetical protein	NA	NA	NA	NA
WP_061871426.1\|1512500_1512764_+	hypothetical protein	NA	NA	NA	NA
WP_080453560.1\|1513307_1513838_+	host-nuclease inhibitor Gam family protein	E9LUU0	Lactobacillus_phage	3.3e-53	58.6
WP_114692974.1\|1513849_1514815_+	hypothetical protein	A6M982	Geobacillus_virus	5.0e-63	53.6
WP_061871423.1\|1514897_1515734_+	DUF4373 domain-containing protein	NA	NA	NA	NA
WP_061871422.1\|1515714_1516557_+	ATP-binding protein	O03914	Lactobacillus_phage	1.8e-157	98.9
WP_061871421.1\|1516689_1516992_+	hypothetical protein	E9LUN7	Lactobacillus_phage	6.3e-41	81.0
WP_061871420.1\|1517358_1519122_-	hypothetical protein	NA	NA	NA	NA
WP_061871419.1\|1519502_1519931_+	transcriptional regulator	E9LUP5	Lactobacillus_phage	1.2e-58	76.6
WP_061871417.1\|1520500_1520935_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_061871836.1\|1521135_1521600_+	hypothetical protein	Q597W0	Lactobacillus_virus	6.3e-32	55.6
WP_061871835.1\|1521583_1522870_+\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	1.1e-115	50.6
WP_114692975.1\|1522859_1524518_+\|portal	phage portal protein	D2IZF6	Enterococcus_phage	4.8e-66	32.6
WP_061871714.1\|1524517_1525462_+\|capsid	minor capsid protein	NA	NA	NA	NA
WP_061871713.1\|1525570_1526218_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_061871712.1\|1526231_1527302_+	hypothetical protein	A0A0S0N2Q7	Pseudomonas_phage	7.7e-33	30.3
WP_061871711.1\|1527316_1527682_+\|head,tail	phage head-tail connector protein	H9A0V3	Staphylococcus_phage	8.8e-05	35.6
WP_069710549.1\|1527686_1528010_+	hypothetical protein	NA	NA	NA	NA
WP_061871709.1\|1527999_1528554_+	hypothetical protein	NA	NA	NA	NA
WP_011101119.1\|1528554_1528941_+	hypothetical protein	NA	NA	NA	NA
WP_053566689.1\|1528952_1529540_+\|tail	phage tail protein	NA	NA	NA	NA
WP_011101121.1\|1529557_1530070_+	hypothetical protein	NA	NA	NA	NA
WP_011101122.1\|1530138_1530375_+	hypothetical protein	NA	NA	NA	NA
WP_061871708.1\|1530374_1534379_+	tape measure protein	E9LUR1	Lactobacillus_phage	5.2e-82	44.3
WP_011101124.1\|1534372_1535110_+	hypothetical protein	A0A1S5SA63	Streptococcus_phage	4.1e-41	36.6
WP_061871707.1\|1535109_1536984_+\|tail	phage tail protein	A0A1X9IGI5	Lactococcus_phage	3.0e-48	32.9
WP_061871706.1\|1536988_1537981_+	SGNH/GDSL hydrolase family protein	Q8LTH0	Staphylococcus_virus	1.8e-36	40.6
WP_011101127.1\|1537995_1538610_+\|plate	phage baseplate upper protein	A0A1J0MFQ3	Staphylococcus_phage	7.3e-44	47.8
WP_011101128.1\|1538615_1539356_+	hypothetical protein	NA	NA	NA	NA
WP_011101129.1\|1539356_1539677_+	DUF2977 domain-containing protein	NA	NA	NA	NA
WP_114692976.1\|1539676_1539853_+	XkdX family protein	NA	NA	NA	NA
WP_061871704.1\|1539830_1540988_+	LysM peptidoglycan-binding domain-containing protein	A0A2K9V5A4	Lactobacillus_phage	8.6e-46	67.2
WP_058011763.1\|1540987_1541251_+	hemolysin XhlA family protein	E9LUR9	Lactobacillus_phage	8.5e-26	73.6
WP_058011762.1\|1541264_1541627_+	hypothetical protein	A0A2H4PBB2	Lactobacillus_phage	2.4e-18	67.1
WP_058011761.1\|1541960_1542167_-	hypothetical protein	NA	NA	NA	NA
WP_058011760.1\|1542418_1542643_-	hypothetical protein	NA	NA	NA	NA
WP_061871703.1\|1542838_1543444_+	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	1.6e-14	28.7
1551469:1551483	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1834508 : 1918511

Lactobacillus_phage(80.43%)

protease,tail,portal,integrase,holin,tRNA,capsid,terminase,head

attL 1860083:1860100|attR 1925375:1925392

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003640716.1\|1834508_1835432_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_003640717.1\|1835909_1836431_-	shikimate kinase	NA	NA	NA	NA
WP_114692994.1\|1836433_1837531_-	prephenate dehydrogenase	NA	NA	NA	NA
WP_013355606.1\|1837533_1838832_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_003645964.1\|1838845_1839373_-	amino acid biosynthesis protein	NA	NA	NA	NA
WP_013355607.1\|1839381_1840551_-	chorismate synthase	NA	NA	NA	NA
WP_015825652.1\|1840543_1841998_-	MFS transporter	NA	NA	NA	NA
WP_003640723.1\|1842646_1843000_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_024002734.1\|1843022_1845599_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	9.6e-21	23.3
WP_003640725.1\|1845613_1845919_-	ribosomal L7Ae/L30e/S12e/Gadd45 family protein	NA	NA	NA	NA
WP_024002733.1\|1845908_1846208_-	YlxR family protein	NA	NA	NA	NA
WP_024002732.1\|1846252_1847470_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_063722222.1\|1847490_1847967_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_003640729.1\|1848262_1852576_-	DNA polymerase III subunit alpha	A0A1X9SH08	Bradyrhizobium_phage	1.0e-14	34.0
WP_003640732.1\|1853069_1854779_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003640733.1\|1854818_1856096_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003640734.1\|1856133_1856919_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_015825653.1\|1856934_1857714_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	1.1e-23	43.1
WP_003640736.1\|1857833_1858397_-	ribosome recycling factor	NA	NA	NA	NA
WP_003640737.1\|1858398_1859121_-	UMP kinase	NA	NA	NA	NA
WP_003644498.1\|1859320_1860199_-	elongation factor Ts	NA	NA	NA	NA
1860083:1860100	attL	NA	NA	NA	NA
WP_003640739.1\|1860301_1861105_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_003640740.1\|1861329_1862052_+	HAD family hydrolase	NA	NA	NA	NA
WP_003640741.1\|1862340_1863339_-	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.3e-47	34.9
WP_003640742.1\|1863423_1863729_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_061871678.1\|1863712_1864471_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_003645630.1\|1864582_1865218_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_003640745.1\|1865274_1865511_-	YneF family protein	NA	NA	NA	NA
WP_003644501.1\|1865608_1865848_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003640747.1\|1865999_1866632_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	56.2
WP_157262971.1\|1866720_1866813_-	DNA alkylation repair protein	NA	NA	NA	NA
WP_015825658.1\|1867187_1867817_+	hypothetical protein	NA	NA	NA	NA
WP_061871677.1\|1867866_1869036_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_003640750.1\|1869071_1869464_-	hypothetical protein	NA	NA	NA	NA
WP_003644503.1\|1869627_1870020_+	hypothetical protein	NA	NA	NA	NA
WP_003640752.1\|1870465_1871407_+	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	2.4e-78	49.0
WP_003645636.1\|1872112_1872685_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003644505.1\|1872836_1874021_-	LCP family protein	NA	NA	NA	NA
WP_003644506.1\|1874001_1874793_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-30	36.8
WP_003644507.1\|1874811_1876554_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_003644508.1\|1877032_1878244_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_013355618.1\|1879483_1880014_-\|holin	holin	E9LUS0	Lactobacillus_phage	6.3e-36	98.8
WP_003644510.1\|1880026_1880290_-	hemolysin XhlA family protein	E9LUR9	Lactobacillus_phage	2.0e-38	100.0
WP_013355619.1\|1880289_1881462_-	LysM peptidoglycan-binding domain-containing protein	E9LUR8	Lactobacillus_phage	1.2e-199	89.5
WP_013355620.1\|1881473_1881833_-	hypothetical protein	A0A2P0ZLF6	Lactobacillus_phage	5.9e-46	80.7
WP_003644513.1\|1881816_1881978_-	hypothetical protein	A0A2P0ZLG1	Lactobacillus_phage	9.5e-20	100.0
WP_013355621.1\|1881981_1882233_-	hypothetical protein	A0A2K9VDF6	Lactobacillus_phage	2.4e-30	98.6
WP_013355622.1\|1882225_1884772_-\|tail	tail fiber protein	A0A2K9VDD0	Lactobacillus_phage	3.0e-248	80.6
WP_013355623.1\|1884788_1887203_-\|tail	phage tail protein	A0A2P0ZLF8	Lactobacillus_phage	0.0e+00	91.3
WP_013355624.1\|1887271_1889044_-\|tail	phage tail family protein	A0A2P0ZLH2	Lactobacillus_phage	7.9e-309	91.9
WP_061871475.1\|1889118_1894149_-	C40 family peptidase	A0A2P0ZLG0	Lactobacillus_phage	0.0e+00	53.1
WP_003644519.1\|1894180_1894372_-	hypothetical protein	NA	NA	NA	NA
WP_003644520.1\|1894410_1894785_-\|tail	phage tail assembly chaperone	A0A2P0ZLH4	Lactobacillus_phage	3.2e-58	96.0
WP_003641402.1\|1894861_1895515_-\|tail	phage tail protein	A0A2P0ZLH1	Lactobacillus_phage	1.5e-111	94.0
WP_013355627.1\|1895530_1895911_-	DUF806 family protein	A0A2P0ZLF4	Lactobacillus_phage	4.5e-60	92.1
WP_013355628.1\|1895910_1896318_-	HK97 gp10 family phage protein	A0A2P0ZLE6	Lactobacillus_phage	2.9e-65	93.8
WP_016511016.1\|1896320_1896668_-\|head	phage head closure protein	A0A2P0ZLF0	Lactobacillus_phage	2.0e-43	73.0
WP_013355629.1\|1896657_1896990_-\|head,tail	phage gp6-like head-tail connector protein	E9LUQ4	Lactobacillus_phage	3.4e-48	91.7
WP_061871476.1\|1897062_1898295_-\|capsid	phage major capsid protein	E9LUQ3	Lactobacillus_phage	1.3e-209	92.4
WP_013355631.1\|1898294_1899050_-\|protease	Clp protease ClpP	E9LUQ2	Lactobacillus_phage	1.5e-123	93.2
WP_013355632.1\|1899027_1900221_-\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	1.3e-222	98.0
WP_003644528.1\|1900223_1900418_-	DUF1056 family protein	E9LUQ0	Lactobacillus_phage	7.4e-27	98.4
WP_016511012.1\|1900407_1902306_-\|terminase	terminase large subunit	E9LUP9	Lactobacillus_phage	0.0e+00	92.6
WP_016511011.1\|1902315_1902771_-\|terminase	phage terminase small subunit P27 family	E9LUP8	Lactobacillus_phage	3.0e-79	96.7
WP_013355635.1\|1902960_1903212_-	hypothetical protein	NA	NA	NA	NA
WP_013355636.1\|1903229_1903499_-	hypothetical protein	NA	NA	NA	NA
WP_013355637.1\|1903504_1903975_-	HNH endonuclease	E9LUP7	Lactobacillus_phage	4.8e-80	91.0
WP_013355638.1\|1903985_1904156_-	hypothetical protein	E9LUP6	Lactobacillus_phage	3.3e-23	96.4
WP_033098961.1\|1904315_1905128_-	hypothetical protein	NA	NA	NA	NA
WP_013355640.1\|1905797_1906226_-	transcriptional regulator	E9LUP5	Lactobacillus_phage	2.9e-63	82.4
WP_013355641.1\|1906500_1906809_-	hypothetical protein	E9LUN7	Lactobacillus_phage	3.2e-48	94.1
WP_013355642.1\|1906944_1907730_-	ATP-binding protein	E9LUN6	Lactobacillus_phage	2.7e-144	98.1
WP_013355643.1\|1907729_1908527_-	hypothetical protein	Q9AZA0	Lactobacillus_prophage	4.2e-52	69.0
WP_033098960.1\|1908628_1908886_-	hypothetical protein	NA	NA	NA	NA
WP_013355644.1\|1908885_1909056_-	hypothetical protein	NA	NA	NA	NA
WP_013355645.1\|1909177_1909330_-	hypothetical protein	E9LUT8	Lactobacillus_phage	8.7e-07	62.5
WP_003641371.1\|1909341_1909542_-	hypothetical protein	E9LUT7	Lactobacillus_phage	1.0e-26	89.4
WP_016511003.1\|1909544_1909793_-	hypothetical protein	E9LUT6	Lactobacillus_phage	2.3e-28	75.0
WP_003641369.1\|1909805_1910009_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003641368.1\|1910174_1910465_+	hypothetical protein	NA	NA	NA	NA
WP_003644548.1\|1911058_1911319_-	hypothetical protein	NA	NA	NA	NA
WP_003644549.1\|1911376_1911733_+	hypothetical protein	NA	NA	NA	NA
WP_003644550.1\|1911729_1911933_-	hypothetical protein	NA	NA	NA	NA
WP_013355646.1\|1911943_1912696_-	phage repressor protein/antirepressor Ant	E9LUT0	Lactobacillus_phage	2.2e-58	96.5
WP_003644552.1\|1912708_1912924_-	hypothetical protein	NA	NA	NA	NA
WP_003641361.1\|1913180_1913507_+	helix-turn-helix transcriptional regulator	A0A1B0Y2R0	Lactobacillus_phage	6.9e-17	44.1
WP_003641360.1\|1913537_1913927_+	ImmA/IrrE family metallo-endopeptidase	D6PSS8	Lactobacillus_phage	4.6e-36	54.3
WP_013355648.1\|1913989_1914868_+	HIRAN domain-containing protein	A0A2H4J549	uncultured_Caudovirales_phage	3.0e-06	34.8
WP_003644554.1\|1914882_1915083_+	hypothetical protein	E9LUS6	Lactobacillus_phage	4.2e-25	97.0
WP_003644556.1\|1916122_1916299_+	hypothetical protein	A0A2P0ZL93	Lactobacillus_phage	7.2e-21	86.2
WP_003644557.1\|1916424_1916682_+	hypothetical protein	A0A2P0ZL96	Lactobacillus_phage	1.0e-31	76.2
WP_003644558.1\|1916865_1917180_+	hypothetical protein	NA	NA	NA	NA
WP_013355651.1\|1917347_1918511_+\|integrase	site-specific integrase	E9LUK6	Lactobacillus_phage	1.0e-62	37.1
1925375:1925392	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2215234 : 2250008

Lactobacillus_phage(64.29%)

tail,portal,holin,capsid,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_114693012.1\|2215234_2215612_-\|holin	holin	A0A2P0ZLG6	Lactobacillus_phage	4.5e-12	59.6
WP_015380597.1\|2215598_2215895_-	hypothetical protein	A0A1I9KK55	Lactobacillus_phage	1.2e-39	77.6
WP_162861283.1\|2215895_2217059_-	LysM peptidoglycan-binding domain-containing protein	O03950	Lactobacillus_phage	7.9e-39	35.9
WP_114693013.1\|2217063_2218554_-	hypothetical protein	NA	NA	NA	NA
WP_114693014.1\|2218567_2219389_-	collagen-like protein	A0A2K9VCB5	Lactobacillus_phage	3.1e-05	31.7
WP_114693015.1\|2219403_2220444_-	hypothetical protein	E9LUJ9	Lactobacillus_phage	8.9e-26	34.4
WP_114693016.1\|2220427_2220838_-	hypothetical protein	NA	NA	NA	NA
WP_114693017.1\|2220834_2221056_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_114693018.1\|2221048_2222176_-\|tail	phage tail protein	O03938	Lactobacillus_phage	4.7e-73	42.6
WP_114693019.1\|2222187_2223006_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_114693020.1\|2223006_2228655_-\|tail	phage tail tape measure protein	Q5ULL6	Lactobacillus_virus	3.6e-36	70.0
WP_114693021.1\|2228670_2229312_-	hypothetical protein	O03936	Lactobacillus_phage	9.7e-07	26.9
WP_114693022.1\|2229308_2229827_-	hypothetical protein	NA	NA	NA	NA
WP_114693023.1\|2229945_2230563_-	hypothetical protein	A0A2I7QIP9	Bacillus_phage	1.4e-05	31.8
WP_015380612.1\|2230580_2231006_-	hypothetical protein	NA	NA	NA	NA
WP_114693024.1\|2231005_2231407_-	hypothetical protein	NA	NA	NA	NA
WP_114693025.1\|2231403_2231793_-	hypothetical protein	NA	NA	NA	NA
WP_076637329.1\|2231793_2232198_-	hypothetical protein	A5GYM1	Lactococcus_phage	2.6e-05	27.5
WP_015380616.1\|2232208_2232469_-	hypothetical protein	NA	NA	NA	NA
WP_041153369.1\|2232557_2233505_-\|capsid	N4-gp56 family major capsid protein	A8ASJ6	Listeria_phage	1.4e-89	59.9
WP_114693026.1\|2233518_2234121_-	hypothetical protein	NA	NA	NA	NA
WP_162861284.1\|2234184_2235270_-	hypothetical protein	A0A059T7W2	Listeria_phage	6.2e-38	30.7
WP_162861285.1\|2235262_2236858_-\|portal	phage portal protein	B5LPR1	Bacillus_virus	7.6e-85	37.5
WP_114693029.1\|2236860_2238186_-\|terminase	PBSX family phage terminase large subunit	A0A1S5SA45	Streptococcus_phage	2.0e-139	55.8
WP_114693030.1\|2238160_2238727_-\|terminase	terminase small subunit	O03926	Lactobacillus_phage	8.8e-44	69.9
WP_114693031.1\|2238780_2238975_-	hypothetical protein	NA	NA	NA	NA
WP_114693032.1\|2239713_2240331_+	hypothetical protein	NA	NA	NA	NA
WP_114693033.1\|2240617_2241067_-	hypothetical protein	B8R690	Lactobacillus_phage	1.8e-12	37.7
WP_114693034.1\|2241240_2241696_-	adenine methyltransferase	A0A2P0ZL79	Lactobacillus_phage	1.8e-68	80.8
WP_114693035.1\|2241698_2241857_-	hypothetical protein	A0A2P0ZLB5	Lactobacillus_phage	4.3e-17	88.5
WP_114693036.1\|2241849_2242230_-	hypothetical protein	NA	NA	NA	NA
WP_114693037.1\|2242226_2242745_-	hypothetical protein	O03915	Lactobacillus_phage	7.8e-39	54.6
WP_114693038.1\|2242749_2243472_-	phage antirepressor KilAC domain-containing protein	Q38585	Streptococcus_virus	6.1e-50	44.6
WP_114693039.1\|2243468_2243756_-	hypothetical protein	NA	NA	NA	NA
WP_114693040.1\|2243752_2244685_-	DUF4373 domain-containing protein	A0A0P0HRQ2	Lactobacillus_phage	2.5e-56	42.0
WP_114693041.1\|2244767_2245733_-	hypothetical protein	A6M982	Geobacillus_virus	2.2e-63	53.6
WP_114693042.1\|2245744_2246275_-	host-nuclease inhibitor Gam family protein	E9LUU0	Lactobacillus_phage	1.8e-54	58.6
WP_114693044.1\|2246734_2247022_+	hypothetical protein	A0A2H4JEH2	uncultured_Caudovirales_phage	4.3e-23	50.0
WP_162044941.1\|2246999_2247161_-	hypothetical protein	NA	NA	NA	NA
WP_024971536.1\|2247271_2247784_-	helix-turn-helix transcriptional regulator	D6PST4	Lactobacillus_phage	2.1e-28	43.5
WP_060684056.1\|2247851_2248157_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_003642792.1\|2248168_2248339_-	hypothetical protein	NA	NA	NA	NA
WP_162861271.1\|2248418_2248604_+	hypothetical protein	NA	NA	NA	NA
WP_154573530.1\|2248584_2248740_-	hypothetical protein	NA	NA	NA	NA
WP_114693046.1\|2248736_2249003_-	helix-turn-helix transcriptional regulator	O03906	Lactobacillus_phage	6.1e-40	96.6
WP_063484859.1\|2249169_2249568_+	helix-turn-helix transcriptional regulator	O03970	Lactobacillus_phage	1.5e-66	95.5
WP_114693047.1\|2249576_2250008_+	hypothetical protein	O03904	Lactobacillus_phage	2.4e-70	86.7

DBSCAN-SWA_9

2449320 : 2457831

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003642593.1\|2449320_2449899_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.9e-22	35.0
WP_003642592.1\|2449891_2450917_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	8.4e-61	41.7
WP_003642591.1\|2450913_2452368_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.5e-50	34.0
WP_021356102.1\|2452352_2454572_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-144	39.1
WP_021356103.1\|2454564_2455245_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003642588.1\|2455244_2455499_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_021356104.1\|2455500_2456232_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	2.1e-37	37.3
WP_024521791.1\|2456234_2457365_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_003645861.1\|2457348_2457831_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-16	41.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage