CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP031241	Haemophilus influenzae strain M17648 chromosome, complete genome	1 crisprs	DEDDh,cas3,csa3,DinG	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP031241_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031241_1

1067196-1067276

Orphan

Consensus_repeat	Method
AAGTTATCAATGAAGGGAACATTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP031241_1

>merge|NZ_CP031241|1|1067196-1067276|CRISPRCasFinder
AAGTTATCAATGAAGGGAACATTACGGCACAAGATTTCGTGGTACTTAATGGCGATGAAGTTATCAATAAAGGGAACATTA

>NZ_CP031241|1|1|1067196-1067276|CRISPRCasFinder
AAGTTATCAATGAAGGGAACATTA	CGGCACAAGATTTCGTGGTACTTAATGGCGATG
AAGTTATCAATAAAGGGAACATTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031241.1\|WP_114934564.1\|1076275_1076917_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_CP031241.1\|WP_005648856.1\|1054889_1055342_-\|TonB-system-energizer-ExbB	unknown	unknown	gnl\|CDD\|131852
NZ_CP031241.1\|WP_005632808.1\|1076940_1077657_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_CP031241.1\|WP_040035501.1\|1075330_1076197_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP031241.1\|WP_112088560.1\|1059975_1060563_-\|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP031241.1\|WP_114934558.1\|1061376_1062420_+\|ADP-heptose--LPS-heptosyltransferase-I	unknown	unknown	gnl\|CDD\|366450
NZ_CP031241.1\|WP_114934560.1\|1070008_1070608_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	unknown	unknown	gnl\|CDD\|234691
NZ_CP031241.1\|WP_074040230.1\|1060574_1061300_-\|3-deoxy-D-manno-octulosonic-acid-kinase	unknown	unknown	gnl\|CDD\|234975
NZ_CP031241.1\|WP_114890129.1\|1077957_1079400_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NZ_CP031241.1\|WP_114934563.1\|1074398_1075331_-\|tRNA-dihydrouridine(16)-synthase-DusC	unknown	unknown	gnl\|CDD\|236713
NZ_CP031241.1\|WP_005668884.1\|1069569_1069926_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|183219
NZ_CP031241.1\|WP_114934556.1\|1056078_1056975_+\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_CP031241.1\|WP_114934562.1\|1072362_1073388_+\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|234593
NZ_CP031241.1\|WP_015701485.1\|1064984_1066676_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP031241.1\|WP_015701484.1\|1062741_1064904_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807
NZ_CP031241.1\|WP_114934561.1\|1070649_1072353_+\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarQ	unknown	unknown	gnl\|CDD\|236800
NZ_CP031241.1\|WP_114934557.1\|1057085_1057715_+\|outer-membrane-protein-assembly-factor-BamC	unknown	unknown	gnl\|CDD\|225854
NZ_CP031241.1\|WP_005668209.1\|1055510_1055978_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|181857
NZ_CP031241.1\|WP_005653397.1\|1057904_1058228_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|182378
NZ_CP031241.1\|WP_005653377.1\|1073513_1074359_+\|RNA-polymerase-sigma-factor-RpoH	unknown	unknown	gnl\|CDD\|235838

Protein	Function_ID	Function_description	E-value
NZ_CP031241.1\|WP_114934564.1\|1076275_1076917_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	2.09178e-86
NZ_CP031241.1\|WP_005648856.1\|1054889_1055342_-\|TonB-system-energizer-ExbB	gnl\|CDD\|131852	TIGR02805, Biopolymer_transport_protein_ExbB, tonB-system energizer ExbB, group 2. Members of this protein family appear to be the ExbB protein of an ExbBD proton-transporting membrane complex that, by means of TonB, energizes transport by TonB-dependent receptors. Note that this family represents one of at least two distinct groups TolQ homologs designated ExbB - see also TIGR02797. Each group associates with a distinct group of ExbD proteins, and a single species may have two ExbB/ExbD/TonB systems. [Transport and binding proteins, Cations and iron carrying compounds].	2.19038e-73
NZ_CP031241.1\|WP_005632808.1\|1076940_1077657_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	1.78122e-179
NZ_CP031241.1\|WP_040035501.1\|1075330_1076197_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	3.49325e-156
NZ_CP031241.1\|WP_112088560.1\|1059975_1060563_-\|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	1.14178e-114
NZ_CP031241.1\|WP_114934558.1\|1061376_1062420_+\|ADP-heptose--LPS-heptosyltransferase-I	gnl\|CDD\|366450	pfam01075, Glyco_transf_9, Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.	5.3698e-99
NZ_CP031241.1\|WP_114934560.1\|1070008_1070608_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	gnl\|CDD\|234691	PRK00220, PRK00220, glycerol-3-phosphate 1-O-acyltransferase PlsY.	6.2397e-101
NZ_CP031241.1\|WP_074040230.1\|1060574_1061300_-\|3-deoxy-D-manno-octulosonic-acid-kinase	gnl\|CDD\|234975	PRK01723, PRK01723, 3-deoxy-D-manno-octulosonic-acid kinase; Reviewed.	8.15904e-130
NZ_CP031241.1\|WP_114890129.1\|1077957_1079400_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP031241.1\|WP_114934563.1\|1074398_1075331_-\|tRNA-dihydrouridine(16)-synthase-DusC	gnl\|CDD\|236713	PRK10550, PRK10550, tRNA dihydrouridine(16) synthase DusC.	0
NZ_CP031241.1\|WP_005668884.1\|1069569_1069926_-\|dihydroneopterin-aldolase	gnl\|CDD\|183219	PRK11593, folB, bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase.	1.59897e-54
NZ_CP031241.1\|WP_114934556.1\|1056078_1056975_+\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	1.4634e-171
NZ_CP031241.1\|WP_114934562.1\|1072362_1073388_+\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|234593	PRK00046, murB, UDP-N-acetylmuramate dehydrogenase.	0
NZ_CP031241.1\|WP_015701485.1\|1064984_1066676_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	3.66575e-128
NZ_CP031241.1\|WP_015701484.1\|1062741_1064904_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	0
NZ_CP031241.1\|WP_114934561.1\|1070649_1072353_+\|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarQ	gnl\|CDD\|236800	PRK10935, PRK10935, nitrate/nitrite two-component system sensor histidine kinase NarQ.	0
NZ_CP031241.1\|WP_114934557.1\|1057085_1057715_+\|outer-membrane-protein-assembly-factor-BamC	gnl\|CDD\|225854	COG3317, NlpB, Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane].	1.57831e-79
NZ_CP031241.1\|WP_005668209.1\|1055510_1055978_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|181857	PRK09437, bcp, thioredoxin-dependent thiol peroxidase; Reviewed.	7.74537e-113
NZ_CP031241.1\|WP_005653397.1\|1057904_1058228_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|182378	PRK10324, PRK10324, ribosome-associated translation inhibitor RaiA.	8.6757e-42
NZ_CP031241.1\|WP_005653377.1\|1073513_1074359_+\|RNA-polymerase-sigma-factor-RpoH	gnl\|CDD\|235838	PRK06596, PRK06596, RNA polymerase factor sigma-32; Reviewed.	0

>NZ_CP031241.1|WP_015701485.1|1064984_1066676_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MRPRYSVIASAVSLGFVLSKSVMALGQPDTGSLNRELEQRRIQSEAKPSGELFNQTANSPYTAQYKQGLKFPLTQVQILDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEFYRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSALSNKFVSRLSNTTVNTSEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKYTGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLDYKLGGNFKSLQSQGHSHTLGAYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYAKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKHNAVENFQPKSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKHYLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEQGVKNSVKLQSVGAGLSLSDAGSYAINVSVAKPLDNNINNADKHQFWLSMIKTF
>NZ_CP031241.1|WP_015701484.1|1062741_1064904_+|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MRFSKLSLAIATTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVAAALEDIPNVDIRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFGVKIRQGYQTANNLSERDVSVFAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRETRFKQTAPSNNEVENELTNEQITDQIREFHKPNNGSPPKAKPSQEEFYSGVKTRFGSVSYLTDQQIPDQSTVFNYYLTPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNNTDAKFRAEPYNANSNTTGVYLIAHIPLFGEKLLISPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQERFVSGAHFGASLIGGLDTINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDANTNKNASASANGALLPLPTKSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKDKFTVGATVTHYAAQRRVPKDHGVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAVYSF
>NZ_CP031241.1|WP_114934558.1|1061376_1062420_+|ADP-heptose--LPS-heptosyltransferase-I
MPLFTKAPKSLCILRLSAVGDVCHALAVVQHIQAYYPQTEMTWIVGKTEMGLLSGIPNVTLIPYDKKAGWKGVLSLWKQLKNKQFDALLNMQTAFRASILSLGIKAKFKIGFGEKRSREGQWLFVNRRIRDPFSPHVLDGFMAFAEYIGVPKAEPKWELAISQDDYKFADQFIDFSRKNLLISPCSSKAEKDWLIERYAEIANIAHQHNVNVIFCSSPAKRELEIVEKITALCHFTPTNIAGKTNLKQLTALISKVDLVLSPDSGPAHIATTQGTPVIGLYAYHNPLRTAPYKNLDNVVSVYEENAQKEFGKPSSELPWATKLKGKNLMAEIQVEPVIEQMKKLGLF
>NZ_CP031241.1|WP_074040230.1|1060574_1061300_-|3-deoxy-D-manno-octulosonic-acid-kinase
MHQFQQDNQYFIFNFDRTFEQATEFFQAEFWQKQERVIGSAKGRGTTYFLQTEDWFGVNCALRHYYRGGLWGKLNKDRYRFSALDTTRSFAEFHLLQRLYEAGLPVPKPIAARIQKGKLGICYQADILTEKIENAQDLTALLQTQTLPKETWRQIGRLIRKLHDLQICHTDLNAHNILLQQAEQEQKCWLIDFDKCGKKSGDFWKVQNLNRLKRSFEKEVGRMNIQFTEQNWADLTAAYHQ
>NZ_CP031241.1|WP_112088560.1|1059975_1060563_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase
MKQKIVLATGNKGKVKEMADVLSNFGFEVIAQTDLGIESPEETGLTFVENALLKARYASEKSGLPAIADDSGLVVSALNGAPGLYSARYAGEEGNDAKNREKLLAELAHVAQDQRQAKFVSCIVFLQHPTDPSPIIAEGECCGVIGFEEKGENGFGYDSLFFSPEQGCTFAELETVEKKKISHRAKALSVLKSKL
>NZ_CP031241.1|WP_005653397.1|1057904_1058228_+|ribosome-associated-translation-inhibitor-RaiA
MTLNITSKQMDITPAIREHLEERLAKLGKWQTQLISPHFVLNKVPNGFSVEASIGTPLGNLLASATSDDMYKAINEVEEKLERQLNKLQHKSESRRADERLKDSFEN
>NZ_CP031241.1|WP_114934557.1|1057085_1057715_+|outer-membrane-protein-assembly-factor-BamC
MKKIILNLITAIILAGCSSNPETLKATNDSFQKSETSIPHFSPLATGGVQLPKADDAYSLPNIEVKKGEDIDIRPPLIPLAIIQNSITKFDGERSLIVYPKQQAKLYNLQQVKRLLKDEGISSTTDGSILTTDWAKTERIGDKSIEIKYQIEQVMTADVSALTVSILHMRRDGIIFTPNVSDKQYYTSERLNRIVLTLTTAYNKQLQDL
>NZ_CP031241.1|WP_114934556.1|1056078_1056975_+|4-hydroxy-tetrahydrodipicolinate-synthase
MSAQNPLFSGSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNALVSVGTTGESATLSIEENIKVIEKTVEFAKGHIPIIAGAGANATSEAITMTKLLRDSGVAGCLSVVPYYNKPTQEGMYQHFKAIAECTDLPQILYNVPIRTGSDMKPETVARLAEIENIVGIKEATGDVSRIVKIKQLAGKNFIVLSGNDATGLEAIKLGAEGVISVTNNIAAKDMADMCRYALAGDFDKAEEINARLMRLHHDLFIESNPIPVKWAAYRLGLIKSPHLRLPLTTLSEEIQPKVEDALKIAGLL
>NZ_CP031241.1|WP_005668209.1|1055510_1055978_-|thioredoxin-dependent-thiol-peroxidase
MNPLSVGNQAPAFTLLNQQEKFVSLNDFRGKKVLIYFYPKALTPGCTTQACGLRDSKSELDALGLVVLGISPDAPKKLAQFIEKKELNFTLLSDPDHQVAEQFGVWGEKKFMGRTYDGIHRISFLINESGNIMQVFDKFKIKDHHQMIIDYLRSL
>NZ_CP031241.1|WP_005648856.1|1054889_1055342_-|TonB-system-energizer-ExbB
MVQLFDFLQQYSDYFIIGLLLLMSIIMLAMVIERYLFLRKVSVAHYSTIHALDIDLNRNMTVISTIGANAPYVGLLGTVIGILLTFYQIGHGGGDIDPSVIMLHLSLALKATALGILVAIPSMVFYNGLGRKVEVNRLKWKVLSEQKDKE
>NZ_CP031241.1|WP_005668884.1|1069569_1069926_-|dihydroneopterin-aldolase
MDRVFIEELTVFAQIGVYDWEQQIKQKLVFDLEMAWDCKQAAETDDVAYCLNYAEVSQAIIDYVESKPFLLIERVAYEVADLLESRYQLQGLKIKLSKPKAVAQARNVGVLIVRGCLK
>NZ_CP031241.1|WP_114934560.1|1070008_1070608_+|glycerol-3-phosphate-1-O-acyltransferase-PlsY
MSLFALFYMLFAYLLGSVSSAILICRIAGLPDPRQNGSHNPGATNVLRIGNRKSALAVLIFDMLKGMIPVWAGYYLGLTQFELGMVALGACLGHIFPIFFQFKGGKGVATAFGAIAPISWAVAGSMFGTWIFVFLVSGYSSLSAVISALLVPFYVWWFKPEFTFPVALVCCLLIYRHHDNVQRLWRGQEDKVWAKFKKK
>NZ_CP031241.1|WP_114934561.1|1070649_1072353_+|nitrate/nitrite-two-component-system-sensor-histidine-kinase-NarQ
MYTKGSVSTRIAKYLFIILIVAGVISSLSLAIMSSNKYDAEAINISGSLRMQSYRLLYEMQEQPESVETNLRRYHISLHSSALLEVQNQFFTPNVLKHSYQNILQRWTNMEKYARQQDVKNYSKQLTNYVADVDYFVFELQRFSEQKWILGVSVLGFAMLLILLMVSYVIWYTNREVVKPLHLMTKASMQVQMRQFNHIPLDTRKQNELGTLARVFTQMSTELGQLYSRLEEAVNEKTQKLRQTNRTLSTLYQSAQLLNTNTINDKILNQVLNYIFISDHLNFVKVEVMGAEHWDITLGKQDANNELQIETLSVDNEELGVLSWQAGLPCPDPRIMQNLAQMLARALYFHKNLRQQEQILLMEERSIIARELHDSLAQVLSFLQIQLTLLKHNLKKEDEQSKEKSLAIIANFEQALSGGYAQLRELLATFRLTIQEANLQLALEQVIDSLRSQTTMQMNVNCQLPSQSLNPQQLVHVLQIVREATTNAIKHSQGTVIEISARINAEGEYEILVEDDGVGIPNLEEPEGHYGLNIMAERCRQLNAQLHIHRREQGGTQVKITLPHTLY
>NZ_CP031241.1|WP_114934562.1|1072362_1073388_+|UDP-N-acetylmuramate-dehydrogenase
MQNLQPFHTFHIQSNAREIIEAHSIEQLQQVWANSKSENLPTLFLGQGSNVLFLDDFNGIVILNRLMGITHEQDANFHYLHVNSGENWHKLVEWSINNGIYGLENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVEVLNLNTNETFRLDTEQCKFGYRESIFKHRYQQGYVITAVGLKLKKDWQPILKYGSLVEFDPKTVTAKQIFDEVCHIRQSKLPDPNEVGNAGSFFKNPVVSSEHFEEIKKHHENLPHFPQEDGSVKLAAGWLIDQCNLKGFQIGGAAVHKKQALVLINKDNASGQDVIKLAYYVRQSVAEKFGVSLQPEVRFISATGEVNSEQIIT
>NZ_CP031241.1|WP_005653377.1|1073513_1074359_+|RNA-polymerase-sigma-factor-RpoH
MDKETQMMLVPQGSIEGYIRAANEYPMLTAEEEKELAERLYYHEDLDAAKKLILSHLRFVIHVARGYSGYGLPQADLIQEGNIGLMKAVKRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNENEVDMVANELGVSKEDVIEMESRMSGADVGFDLPTDDAETETYSPALYLEDKSSNFAAELENENFESQATEQLSAALQSLDARSQDIIKARWLDDNKATLHDLAAKYNVSAERIRQLETNALKKLKSAVNF
>NZ_CP031241.1|WP_114934563.1|1074398_1075331_-|tRNA-dihydrouridine(16)-synthase-DusC
MRVILAPMQGVLDPFVRQLLTEVNDYDLCITEFVRVVDQLLPEKVFYRLCPELKNQGFTSSGTPVRVQLLGQNPECLAENAIRAIDLGSHGVDLNCGCPSKTVNGSNGGAALLKQPELIYCATQALRKAVPSEFPVSVKVRLGWDDISQAFEIADAVEQGGATEITVHGRTKADGYRADRINWKKISEVRERLSIPVIANGEIWHWQDGQDCLSQTGCQDLMVGRGALNIPNLSHVLKSNAEKMPWYEIQKILQKYANVENEYDSGFYHVARIKQWLRYLNKEYNEANQVFDKIKTCQTAEDLKLRLNEK
>NZ_CP031241.1|WP_040035501.1|1075330_1076197_-|co-chaperone-DjlA
MEFIGKIIGVFLGWKVGGFFGAIAGLILGSIADKKLYELGSVSSSFFKKKTTRQDLFMQTTFAVLGHLSKSKGRVTEEDIQLANQLMIQLKLDDAGRKLAQDAFRRGKESDFPIRQVIREFRIGCGQRADLLRMFLQVQVQAAFADSELHENEKEVLYVIAEELGLSRMQFEQMIAMEMAARAFTQGGFYQQYQQGAYQGGYQYQQQNSGGYQHASGPTLNDAYKVLGVTESDEQSTVKRAYRRLMNEHHPDKLVAKGLPPEMMEMAKEKTQQIQAAYDLICQAKGWK
>NZ_CP031241.1|WP_114934564.1|1076275_1076917_-|orotate-phosphoribosyltransferase
MEQYKRNFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGADLARLGEFYAAAIQANAVDFDVVFGPAYKGIPIGTSVSVALFNRYGIDKPVCFNRKEVKDHGEGGNLIGSPLQGKILLVDDVITAGTAIRESMELISANKAELAAVLIALNRKERGKGELSAIQEVERDYQCQVLSIIDLDDLMQFIEQDPRYSSHLPEMCAYRAEFGV
>NZ_CP031241.1|WP_005632808.1|1076940_1077657_-|ribonuclease-PH
MRPNNRENNQPRQIKITRNYTKHAEGSVLVEFGDTKVLCTATVEDAVPRFLKGQGQGWVTAEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAMVDLKALGERAITLDCDVIQADGGTRTASITGAAVALCDAINGLIENGTLKTNPIKGLVSAISVGIVDGQAVCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLTLLDLAKQGCNQIFIAQREALGL
>NZ_CP031241.1|WP_114890129.1|1077957_1079400_-|glutamate--tRNA-ligase
MKLDAPFNLDPNVKVRTRFAPSPTGYLHVGGARTALYSWLYAKHNNGEFVLRIEDTDLERSTPEATAAIIEGMEWLNLPWEHGPYYQTKRFDRYNQVIDEMIEQGLAYRCYCTKEHLEELRHTQEQNKEKPRYDRHCLHDHNHSPDEPHVVRFKNPTEGSVVFDDAVRGRIEISNSELDDLIIRRTDGSPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINILKAIGAPIPTYAHVSMINGDDGQKLSKRHGAVSVMQYRDDGYLPEALINYLVRLGWGHGDQEIFSREEMINYFELDHVSKSASAFNTEKLQWLNQHYIRELPPEYVAKHLEWHYKDQGINTTNGPALTEIVTMLAERCKTLKEMARSSRYFFEEFETFDEAAAKKHFKGNAAEALAKVKEKLTALSSWDLHSTHEAIEQTAAELEVGMGKVGMPLRVAVTGSGQSPSMDVTLVGIGRDRVLARIQRAIDFIHAQNA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

69177 : 78246

Escherichia_phage(83.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_112102649.1\|69177_69678_-	ferredoxin-type protein NapF	A0A077SLP0	Escherichia_phage	3.5e-12	31.4
WP_050948635.1\|69677_70289_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	3.0e-21	32.5
WP_114934359.1\|70400_71240_-	dimethyl sulfoxide reductase anchor subunit	A0A077SK59	Escherichia_phage	1.7e-19	32.2
WP_005647791.1\|71241_71859_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	7.5e-73	57.3
WP_114890502.1\|71869_74290_-	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	2.4e-223	50.4
WP_042611482.1\|74543_75653_+	transglutaminase family protein	NA	NA	NA	NA
WP_005651689.1\|75627_75990_+	membrane protein	NA	NA	NA	NA
WP_015702037.1\|75998_76277_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_114890501.1\|76401_78246_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	4.8e-22	29.3

DBSCAN-SWA_2

208945 : 217459

Planktothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005663823.1\|208945_209929_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-20	32.8
WP_005694258.1\|209931_210924_-	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.0e-14	30.8
WP_005653671.1\|210933_211821_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_162816658.1\|211835_212837_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_162816672.1\|212926_215107_-	DNA helicase II	A7KV33	Bacillus_phage	1.1e-115	37.6
WP_005686506.1\|215721_216357_-	7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	8.7e-16	30.3
WP_114934394.1\|216378_216783_-	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	3.7e-20	43.3
WP_112071454.1\|216775_217459_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	8.6e-54	50.2

DBSCAN-SWA_3

415424 : 470844

Aggregatibacter_phage(20.59%)

holin,capsid,tail,terminase,tRNA,integrase

attL 448896:448924|attR 474289:474317

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_112088637.1\|415424_416366_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.2e-122	82.7
WP_005666957.1\|416515_417850_+	chromosome partition protein MukF	NA	NA	NA	NA
WP_114890378.1\|417896_418628_+	chromosome partition protein MukE	NA	NA	NA	NA
WP_114890377.1\|418627_423160_+	chromosome partition protein MukB	NA	NA	NA	NA
WP_114890376.1\|423230_424139_+	hypothetical protein	NA	NA	NA	NA
WP_114890375.1\|424142_425018_+	EamA/RhaT family transporter	NA	NA	NA	NA
WP_114890374.1\|425030_426452_+	exodeoxyribonuclease I	NA	NA	NA	NA
WP_005691999.1\|427181_428459_-	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	7.1e-25	30.6
WP_005650606.1\|428455_429151_-	phosphate regulon transcriptional regulatory protein PhoB	NA	NA	NA	NA
WP_005650603.1\|429247_430015_-	phosphate ABC transporter ATP-binding protein PstB	G3M9Y6	Bacillus_virus	1.6e-16	30.0
WP_114890373.1\|430024_430873_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_005656744.1\|430874_431822_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_005653946.1\|431913_432933_-	phosphate ABC transporter substrate-binding protein PstS	A0A222YW41	Synechococcus_phage	1.2e-51	40.5
WP_005650594.1\|433437_433926_+	non-heme ferritin	NA	NA	NA	NA
WP_005650592.1\|433941_434439_+	non-heme ferritin	NA	NA	NA	NA
WP_005671001.1\|434726_434894_+	hypothetical protein	NA	NA	NA	NA
WP_114934440.1\|434999_436556_+	anthranilate synthase component I	A0A0B5J984	Pandoravirus	1.8e-22	33.2
WP_114890371.1\|436568_437150_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.7e-34	40.4
WP_005666933.1\|437198_437585_+	tautomerase family protein	NA	NA	NA	NA
WP_114890370.1\|437637_438639_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.2e-43	38.1
WP_162816674.1\|438678_440109_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	1.6e-33	38.0
WP_110431867.1\|440239_440512_+	hydrogenase maturation factor HybG	NA	NA	NA	NA
WP_114934442.1\|440545_443410_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.0e-148	37.3
WP_114934443.1\|443808_444117_-	ASCH domain-containing protein	NA	NA	NA	NA
WP_114890364.1\|444120_444555_-	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_114890363.1\|444789_446184_+	class II fumarate hydratase	NA	NA	NA	NA
WP_114890362.1\|446311_446920_+	hypothetical protein	NA	NA	NA	NA
WP_114890361.1\|447018_447843_-	PHP domain-containing protein	NA	NA	NA	NA
WP_114890360.1\|447842_448862_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
448896:448924	attL	NA	NA	NA	NA
WP_114890359.1\|449092_449731_-\|tail	tail fiber protein	Q94MY0	Haemophilus_virus	4.9e-35	52.8
WP_114890358.1\|449763_450219_-	DUF2612 domain-containing protein	D0UIH4	Aggregatibacter_phage	1.3e-58	77.2
WP_114934444.1\|450231_451332_-	DUF2213 domain-containing protein	Q7Y5U2	Haemophilus_phage	8.8e-141	87.0
WP_162790539.1\|451472_452654_-\|capsid	minor capsid protein	Q7Y5U5	Haemophilus_phage	7.1e-88	76.3
WP_114934445.1\|452682_454014_-	DUF1073 domain-containing protein	D0UIJ6	Aggregatibacter_phage	1.2e-216	86.5
WP_114934446.1\|454015_455395_-\|terminase	phage terminase large subunit	D0UIJ7	Aggregatibacter_phage	5.7e-246	88.7
WP_114890353.1\|455414_455987_-\|terminase	terminase small subunit	Q7Y5U8	Haemophilus_phage	6.2e-21	42.5
WP_114890352.1\|455996_456518_-	Rha family transcriptional regulator	A0A0P0HSR5	Acinetobacter_phage	1.4e-19	34.3
WP_114934447.1\|456645_456927_-	hypothetical protein	Q776X1	Haemophilus_phage	3.2e-31	74.4
WP_114890351.1\|456838_457162_-	DUF2570 family protein	Q7Y5U9	Haemophilus_phage	2.8e-23	61.1
WP_114934448.1\|457154_457757_-	glycoside hydrolase family 19 protein	Q7Y5V0	Haemophilus_phage	1.6e-56	53.9
WP_013525935.1\|457725_458082_-\|holin	phage holin, lambda family	NA	NA	NA	NA
WP_162790517.1\|458836_459640_-	hypothetical protein	D0UIK6	Aggregatibacter_phage	4.6e-62	48.3
WP_114890347.1\|460079_460265_+	hypothetical protein	A0A0M3LQV3	Mannheimia_phage	1.5e-05	45.5
WP_114890346.1\|460322_460694_-	hypothetical protein	NA	NA	NA	NA
WP_114890345.1\|460690_461233_-	recombination protein NinG	D0UIK8	Aggregatibacter_phage	3.3e-56	62.1
WP_005633909.1\|461776_462001_-	hypothetical protein	A0A0M3LR43	Mannheimia_phage	1.1e-10	47.9
WP_114890344.1\|461997_462618_-	replication P	A0A0M3LS65	Mannheimia_phage	1.0e-29	39.7
WP_114934449.1\|462614_463313_-	helix-turn-helix domain-containing protein	D0UIL5	Aggregatibacter_phage	3.0e-62	61.5
WP_114934450.1\|463309_463978_-	hypothetical protein	D0UIL6	Aggregatibacter_phage	2.0e-55	52.1
WP_015702309.1\|464025_464322_-	hypothetical protein	Q7Y5W3	Haemophilus_phage	1.5e-31	70.4
WP_114890342.1\|464679_465336_+	LexA family transcriptional regulator	A0A0M3LSL8	Mannheimia_phage	1.2e-65	58.4
WP_114890341.1\|466403_466778_+	ASCH domain-containing protein	Q938L5	Temperate_phage	3.7e-22	46.7
WP_080281387.1\|467200_467374_-	DUF1508 domain-containing protein	A0A2P1N580	Mycobacterium_phage	2.4e-08	65.0
WP_005692473.1\|467387_467597_+	hypothetical protein	NA	NA	NA	NA
WP_005687158.1\|467923_468163_+	hypothetical protein	A0A0M3LPU3	Mannheimia_phage	3.2e-11	48.6
WP_005687157.1\|468148_468415_-	hypothetical protein	A0A0N9STP5	Staphylococcus_phage	5.6e-09	49.2
WP_114934452.1\|468675_469167_+	helicase	NA	NA	NA	NA
WP_005656638.1\|469170_469263_+	hypothetical protein	NA	NA	NA	NA
WP_103746124.1\|470149_470428_+	hypothetical protein	NA	NA	NA	NA
WP_162816675.1\|470424_470844_-\|integrase	tyrosine-type recombinase/integrase	A0A0M3LQN1	Mannheimia_phage	3.8e-20	58.2
474289:474317	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage