CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP031245	Streptococcus pneumoniae strain M16808 chromosome, complete genome	2 crisprs	DEDDh,PrimPol,cas3,DinG	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP031245_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031245_1

69217-69302

Orphan

Consensus_repeat	Method
TTTTTGAAACGTTTCATTTTTGCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP031245_1

>merge|NZ_CP031245|1|69217-69302|CRISPRCasFinder
TTTTTGAAACGTTTCATTTTTGCTTGAAAAAGATAGCGCTTGGCGCTGTCTATTTATTTTGTTTTTGAAACGTTTCATTTTTGTTT

>NZ_CP031245|1|1|69217-69302|CRISPRCasFinder
TTTTTGAAACGTTTCATTTTTGCTT	GAAAAAGATAGCGCTTGGCGCTGTCTATTTATTTTG
TTTTTGAAACGTTTCATTTTTGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031245.1\|WP_001809002.1\|72647_72812_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP031245.1\|WP_050096564.1\|77305_78781_-\|arylsulfatase	unknown	unknown	gnl\|CDD\|237491
NZ_CP031245.1\|WP_000797956.1\|67386_68277_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP031245.1\|WP_000818078.1\|62087_62327_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031245.1\|WP_001809903.1\|61743_61923_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031245.1\|WP_000109957.1\|74321_74525_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP031245.1\|WP_000961810.1\|60938_61391_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NZ_CP031245.1\|WP_054387466.1\|62596_63868_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP031245.1\|WP_000064115.1\|73682_74291_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP031245.1\|WP_001084979.1\|68287_69205_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NZ_CP031245.1\|WP_000455066.1\|73473_73644_+\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834
NZ_CP031245.1\|WP_000502560.1\|64412_65732_-\|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl\|CDD\|224536
NZ_CP031245.1\|WP_001865109.1\|75110_75398_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP031245.1\|WP_054387476.1\|61427_61607_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP031245.1\|WP_054387465.1\|60177_60648_-\|DUF3013-family-protein	unknown	unknown	gnl\|CDD\|337951
NZ_CP031245.1\|WP_050278164.1\|65741_67358_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270299
NZ_CP031245.1\|WP_000030213.1\|72895_73462_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	unknown	unknown	gnl\|CDD\|380217
NZ_CP031245.1\|WP_000782429.1\|76460_77309_-\|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl\|CDD\|335469
NZ_CP031245.1\|WP_001205275.1\|70723_72205_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|285470
NZ_CP031245.1\|WP_000229339.1\|75675_76446_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667

Protein	Function_ID	Function_description	E-value
NZ_CP031245.1\|WP_001809002.1\|72647_72812_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	6.92661e-06
NZ_CP031245.1\|WP_050096564.1\|77305_78781_-\|arylsulfatase	gnl\|CDD\|237491	PRK13759, PRK13759, arylsulfatase; Provisional.	0
NZ_CP031245.1\|WP_000797956.1\|67386_68277_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.96339e-67
NZ_CP031245.1\|WP_054387466.1\|62596_63868_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP031245.1\|WP_000109957.1\|74321_74525_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	1.20386e-07
NZ_CP031245.1\|WP_000961810.1\|60938_61391_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.2282e-11
NZ_CP031245.1\|WP_000064115.1\|73682_74291_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	1.35166e-33
NZ_CP031245.1\|WP_001084979.1\|68287_69205_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	1.73729e-138
NZ_CP031245.1\|WP_000455066.1\|73473_73644_+\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	9.45975e-16
NZ_CP031245.1\|WP_000502560.1\|64412_65732_-\|glycoside-hydrolase-family-32-protein	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	2.85449e-178
NZ_CP031245.1\|WP_001865109.1\|75110_75398_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.62746e-14
NZ_CP031245.1\|WP_054387476.1\|61427_61607_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.84204e-06
NZ_CP031245.1\|WP_054387465.1\|60177_60648_-\|DUF3013-family-protein	gnl\|CDD\|337951	pfam11217, DUF3013, Protein of unknown function (DUF3013). This bacterial family of proteins with unknown function appear to be restricted to Firmicutes.	2.61986e-66
NZ_CP031245.1\|WP_050278164.1\|65741_67358_-\|extracellular-solute-binding-protein	gnl\|CDD\|270299	cd13581, PBP2_AlgQ_like_2, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	0
NZ_CP031245.1\|WP_000030213.1\|72895_73462_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	7.65552e-46
NZ_CP031245.1\|WP_000782429.1\|76460_77309_-\|formylglycine-generating-enzyme-family-protein	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	3.26408e-66
NZ_CP031245.1\|WP_001205275.1\|70723_72205_-\|aspartate-aminotransferase	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	2.22789e-74
NZ_CP031245.1\|WP_000229339.1\|75675_76446_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.14768e-16

>NZ_CP031245.1|WP_001084979.1|68287_69205_-|sugar-ABC-transporter-permease
MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLIAFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAIMLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLTNPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPALKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTAVGLFNAVINVVLLVAVNQIVKRMNNGEGI
>NZ_CP031245.1|WP_000797956.1|67386_68277_-|carbohydrate-ABC-transporter-permease
MKNSIMDTKFDRRILLLNKIIIVFIVLITLLPLLYIVVASFMDPKVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPLSKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKDLGMLNTPWAIIVPGAVNVWNIILARAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIVMYPFFQKYFDKGIMAGSLKG
>NZ_CP031245.1|WP_050278164.1|65741_67358_-|extracellular-solute-binding-protein
MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQEKKTLKFMTASSPLAPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDLPDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHIYSFPWIEELGEGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNGNGEADEIPFTFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVKFIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAGPSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQQNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLDLIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWDDYKKELEKYGLSDYLAIKQKYYDQYQANKN
>NZ_CP031245.1|WP_000502560.1|64412_65732_-|glycoside-hydrolase-family-32-protein
MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNGFVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSGSAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVVTGTDLPDELIAADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMWECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDHGQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQFPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTSRRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID
>NZ_CP031245.1|WP_054387466.1|62596_63868_+|replication-associated-recombination-protein-A
MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIHHITLDIMENSLQRSYITMDNDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYVAMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYFQAEDTGKYERALAQRKEAIDHLRKI
>NZ_CP031245.1|WP_000818078.1|62087_62327_-|hypothetical-protein
MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK
>NZ_CP031245.1|WP_001809903.1|61743_61923_-|hypothetical-protein
MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH
>NZ_CP031245.1|WP_054387476.1|61427_61607_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MPMTQKEMVKLLTAHGWIKTRGGKGSHIKIEKQGERPITILHGELNKYTERGIGKQVGL
>NZ_CP031245.1|WP_000961810.1|60938_61391_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAMGSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSVDVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA
>NZ_CP031245.1|WP_054387465.1|60177_60648_-|DUF3013-family-protein
MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNAAGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYFVLFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY
>NZ_CP031245.1|WP_001205275.1|70723_72205_-|aspartate-aminotransferase
MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE
>NZ_CP031245.1|WP_001809002.1|72647_72812_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVITVVSFFTGRK
>NZ_CP031245.1|WP_000030213.1|72895_73462_+|alkaline-shock-response-membrane-anchor-protein-AmaP
MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNSVVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFVRSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFGIERQVKLEVAVKNYQPKPQNKKTVSRVK
>NZ_CP031245.1|WP_000455066.1|73473_73644_+|DUF2273-domain-containing-protein
MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVAAGLYIEKNYIDK
>NZ_CP031245.1|WP_000064115.1|73682_74291_+|Asp23/Gls24-family-envelope-stress-response-protein
MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLENVSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSEIREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQFEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN
>NZ_CP031245.1|WP_000109957.1|74321_74525_+|CsbD-family-protein
MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVAEDAKDAVEGAVEGVKNMLSGDDK
>NZ_CP031245.1|WP_001865109.1|75110_75398_+|IS30-family-transposase
MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF
>NZ_CP031245.1|WP_000229339.1|75675_76446_-|sulfite-exporter-TauE/SafE-family-protein
MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIAFYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVRLVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNVSLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGGVLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL
>NZ_CP031245.1|WP_000782429.1|76460_77309_-|formylglycine-generating-enzyme-family-protein
MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPVTNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKHPYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDTLLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRYTLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLGFRCLKE
>NZ_CP031245.1|WP_050096564.1|77305_78781_-|arylsulfatase
MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVDLIDDGMDCNSWEARPWDKDEKLHPTNWVVSESILFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALGGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS

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Crispr_ID: NZ_CP031245_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP031245_2

662683-662778

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP031245_2

>merge|NZ_CP031245|2|662683-662778|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>NZ_CP031245|2|2|662683-662778|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP031245.1\|WP_016398064.1\|669783_670356_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NZ_CP031245.1\|WP_054387514.1\|658689_659550_+\|DUF4299-domain-containing-protein	unknown	unknown	gnl\|CDD\|339103
NZ_CP031245.1\|WP_001030032.1\|657581_658568_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NZ_CP031245.1\|WP_001233684.1\|660854_661766_-\|DUF4097-domain-containing-protein	unknown	unknown	gnl\|CDD\|372574
NZ_CP031245.1\|WP_050081725.1\|664027_665185_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
NZ_CP031245.1\|WP_000838912.1\|668870_669542_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP031245.1\|WP_114880847.1\|667055_667223_-\|lysyl-tRNA-synthetase	unknown	unknown	unknown
NZ_CP031245.1\|WP_054387515.1\|662803_663970_-\|CynX/NimT-family-MFS-transporter	unknown	unknown	gnl\|CDD\|225365
NZ_CP031245.1\|WP_050079501.1\|671179_671428_+\|lactococcin-972-family-bacteriocin	unknown	unknown	gnl\|CDD\|273735
NZ_CP031245.1\|WP_001075102.1\|654701_655625_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP031245.1\|WP_050081730.1\|665226_667077_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP031245.1\|WP_050079505.1\|659727_660792_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370966
NZ_CP031245.1\|WP_000200894.1\|667335_667968_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798
NZ_CP031245.1\|WP_000800407.1\|655834_657310_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
NZ_CP031245.1\|WP_000273863.1\|662338_662665_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP031245.1\|WP_000500040.1\|667989_668862_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP031245.1\|WP_001189285.1\|670407_670728_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP031245.1\|WP_000714582.1\|653758_654688_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NZ_CP031245.1\|WP_000198688.1\|661758_662352_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NZ_CP031245.1\|WP_001810745.1\|653218_653440_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP031245.1\|WP_016398064.1\|669783_670356_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.19314e-14
NZ_CP031245.1\|WP_054387514.1\|658689_659550_+\|DUF4299-domain-containing-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	1.43799e-116
NZ_CP031245.1\|WP_001030032.1\|657581_658568_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
NZ_CP031245.1\|WP_001233684.1\|660854_661766_-\|DUF4097-domain-containing-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	1.69827e-38
NZ_CP031245.1\|WP_050081725.1\|664027_665185_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	6.9736e-109
NZ_CP031245.1\|WP_000838912.1\|668870_669542_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
NZ_CP031245.1\|WP_054387515.1\|662803_663970_-\|CynX/NimT-family-MFS-transporter	gnl\|CDD\|225365	COG2807, CynX, Cyanate permease [Inorganic ion transport and metabolism].	1.90802e-125
NZ_CP031245.1\|WP_001075102.1\|654701_655625_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69
NZ_CP031245.1\|WP_050081730.1\|665226_667077_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP031245.1\|WP_050079505.1\|659727_660792_-\|hypothetical-protein	gnl\|CDD\|370966	pfam10310, DUF5427, Family of unknown function (DUF5427). This is a domain of unknown function. Family members found in Saccharomyces cerevisiae, are synthetic lethal with genes involved in maintenance of telomere capping. However, experimental evidence is yet to verify the exact function of family members and the domain.	2.35909e-05
NZ_CP031245.1\|WP_000200894.1\|667335_667968_-\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.25443e-98
NZ_CP031245.1\|WP_000800407.1\|655834_657310_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.24398e-44
NZ_CP031245.1\|WP_000273863.1\|662338_662665_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	8.86871e-19
NZ_CP031245.1\|WP_000500040.1\|667989_668862_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.44295e-105
NZ_CP031245.1\|WP_000714582.1\|653758_654688_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
NZ_CP031245.1\|WP_000198688.1\|661758_662352_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	1.19707e-63
NZ_CP031245.1\|WP_050079501.1\|671179_671428_+\|lactococcin-972-family-bacteriocin	gnl\|CDD\|273735	TIGR01653, hypothetical_protein, bacteriocin, lactococcin 972 family. This model represents bacteriocins related to lactococcin 972. Members tend to be found in association with a seven transmembrane putative immunity protein. [Cellular processes, Toxin production and resistance].	1.49158e-20

>NZ_CP031245.1|WP_000273863.1|662338_662665_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGSIRHDKN
>NZ_CP031245.1|WP_000198688.1|661758_662352_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGASSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA
>NZ_CP031245.1|WP_001233684.1|660854_661766_-|DUF4097-domain-containing-protein
MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIYDSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAENIQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>NZ_CP031245.1|WP_050079505.1|659727_660792_-|hypothetical-protein
MKQEWFESNDFIKTTSKNKPEEQAQEVADKAEETIADLDTPIEKNTQLEEEVSQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>NZ_CP031245.1|WP_054387514.1|658689_659550_+|DUF4299-domain-containing-protein
MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQPLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVNLPDLLTKTDWLIIKSFLDALLAYTGTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLAQFEARVRAVQETDAYFARVSFYQDREGEVHGVYRLAQGVKTVLPREPFVPAAYIEQLMDKEVQWEIDLIQITGDGSKPEDYEAIACLDYAKFLEVLPLSFYHQLDANQIEVQPILDKDFKTLAQEK
>NZ_CP031245.1|WP_001030032.1|657581_658568_+|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>NZ_CP031245.1|WP_000800407.1|655834_657310_+|DUF3502-domain-containing-protein
MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>NZ_CP031245.1|WP_001075102.1|654701_655625_+|carbohydrate-ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>NZ_CP031245.1|WP_000714582.1|653758_654688_+|sugar-ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>NZ_CP031245.1|WP_001810745.1|653218_653440_+|hypothetical-protein
MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLFLADEKGSEHTEAELIDNLKEVIAKLKANA
>NZ_CP031245.1|WP_054387515.1|662803_663970_-|CynX/NimT-family-MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSIGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL
>NZ_CP031245.1|WP_050081725.1|664027_665185_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML
>NZ_CP031245.1|WP_050081730.1|665226_667077_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>NZ_CP031245.1|WP_114880847.1|667055_667223_-|lysyl-tRNA-synthetase
MARTDEVSNHTYGKATLTWFEEIFEEYKSLHNKTHITKVVNLILCVFLFYSMWVV
>NZ_CP031245.1|WP_000200894.1|667335_667968_-|HAD-family-hydrolase
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>NZ_CP031245.1|WP_000500040.1|667989_668862_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>NZ_CP031245.1|WP_000838912.1|668870_669542_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>NZ_CP031245.1|WP_016398064.1|669783_670356_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETVSAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>NZ_CP031245.1|WP_001189285.1|670407_670728_-|hypothetical-protein
MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTLLEDAKNKKSYDRLVICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQAKER
>NZ_CP031245.1|WP_050079501.1|671179_671428_+|lactococcin-972-family-bacteriocin
MVCSILASTSVLAVWVDGGQWNYGVGWTGTFGYSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

138843 : 146174

uncultured_Mediterranean_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167838.1\|138843_139545_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.6e-34	36.5
WP_000777248.1\|139966_140926_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.0e-57	40.8
WP_001193669.1\|140915_141872_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_114880766.1\|141868_142621_+	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	2.4e-12	30.2
WP_050221118.1\|142716_143682_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000821640.1\|143906_144149_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.3e-17	59.4
WP_001222228.1\|144148_144871_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000105310.1\|144857_145427_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
WP_000351912.1\|145445_146174_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	6.9e-09	22.3

DBSCAN-SWA_2

508245 : 619155

100

Streptococcus_phage(64.62%)

portal,head,protease,capsid,bacteriocin,tRNA,transposase,holin,tail,integrase,terminase

attL 555072:555092|attR 589733:589753

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000510408.1\|508245_509085_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	1.5e-15	32.6
WP_000835715.1\|509069_509897_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	3.5e-17	33.3
WP_000712141.1\|509893_510439_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_001227958.1\|510449_511271_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000170211.1\|511312_512596_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	8.4e-18	30.0
WP_000424275.1\|512592_513843_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.5e-93	42.3
WP_000455903.1\|514001_514370_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	57.3
WP_000266669.1\|514372_515470_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000073428.1\|515520_516999_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	40.5
WP_000165444.1\|517150_518176_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000958770.1\|518381_520004_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.4e-48	26.2
WP_114880799.1\|520065_522618_+	YfhO family protein	NA	NA	NA	NA
WP_000579435.1\|523483_524251_-	YhgE/Pip domain-containing protein	NA	NA	NA	NA
WP_050123485.1\|524429_524972_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000866065.1\|525213_525966_-	response regulator transcription factor	NA	NA	NA	NA
WP_000362880.1\|525962_527288_-	sensor histidine kinase	NA	NA	NA	NA
WP_000799689.1\|527308_527434_-	competence-stimulating peptide ComC	NA	NA	NA	NA
WP_000695929.1\|527715_528195_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_000681601.1\|528377_529559_+\|protease	serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-16	26.1
WP_000410378.1\|529616_530375_+	ParB/RepB/Spo0J family partition protein	S5VSZ7	Leptospira_phage	1.6e-16	36.1
WP_000660615.1\|530587_531949_+	chromosomal replication initiator protein DnaA	NA	NA	NA	NA
WP_000581157.1\|532107_533244_+	DNA polymerase III subunit beta	A0A0A8IL17	Aurantimonas_phage	1.6e-23	24.4
WP_000285194.1\|533308_533503_+	DUF951 family protein	NA	NA	NA	NA
WP_001218707.1\|533586_534702_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_000163931.1\|534772_535342_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_054387394.1\|535342_538852_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_001234978.1\|538909_539176_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_000041909.1\|539168_539537_+	septum formation initiator family protein	NA	NA	NA	NA
WP_001224760.1\|539656_540925_+	serine hydrolase	NA	NA	NA	NA
WP_001208988.1\|540921_542199_+\|tRNA	tRNA lysidine(34) synthetase TilS	A7K9Y8	Acanthocystis_turfacea_chlorella_virus	2.5e-06	24.1
WP_050221011.1\|542202_542745_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	9.4e-11	29.5
WP_000744557.1\|542760_544719_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	H8ZJI5	Ostreococcus_tauri_virus	3.2e-109	45.8
WP_114880800.1\|544783_546031_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.2e-221	92.6
WP_000588874.1\|546254_546734_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_000939545.1\|553223_553460_+	hypothetical protein	NA	NA	NA	NA
WP_000205044.1\|553690_554977_+	adenylosuccinate synthase	L7Y4J5	Megavirus	2.7e-72	37.1
555072:555092	attL	NA	NA	NA	NA
WP_000876732.1\|555218_556367_-\|integrase	site-specific integrase	A0A1S5SEH2	Streptococcus_phage	1.6e-217	100.0
WP_000122591.1\|556552_557476_-	DNA polymerase III subunit epsilon	A0A1S5SEW3	Streptococcus_phage	3.5e-175	100.0
WP_001865140.1\|557488_557872_-	hypothetical protein	A0A141DZD2	Streptococcus_phage	1.5e-66	100.0
WP_000492031.1\|557884_558250_-	helix-turn-helix transcriptional regulator	A0A1S5SEP7	Streptococcus_phage	3.2e-63	100.0
WP_000842471.1\|558555_559038_-	hypothetical protein	A0A1S5S9P0	Streptococcus_phage	8.4e-80	100.0
WP_000032096.1\|559092_559296_+	hypothetical protein	A0A1S5S9L1	Streptococcus_phage	1.2e-27	100.0
WP_001057654.1\|559312_559510_+	hypothetical protein	A0A1S5SEL5	Streptococcus_phage	3.6e-29	100.0
WP_001865135.1\|559625_560285_-	hypothetical protein	A0A1S5S8Z0	Streptococcus_phage	1.0e-120	100.0
WP_001865134.1\|560338_561055_+	hypothetical protein	A0A141DZC7	Streptococcus_phage	4.7e-135	100.0
WP_000370959.1\|561067_561325_+	hypothetical protein	A0A1S5SEV6	Streptococcus_phage	1.2e-43	100.0
WP_000462826.1\|561410_561731_+	hypothetical protein	A0A1S5SGB9	Streptococcus_phage	7.4e-48	100.0
WP_001865133.1\|561746_562043_+	hypothetical protein	A0A141DZC5	Streptococcus_phage	8.9e-48	100.0
WP_054387342.1\|562035_562842_+	DnaD domain protein	E8ZDM9	Streptococcus_phage	3.7e-136	91.7
WP_000228214.1\|562981_563752_+	ATP-binding protein	A0A1S5S8G3	Streptococcus_phage	5.2e-140	100.0
WP_050267377.1\|563960_564188_+	hypothetical protein	A0A1S5SCL8	Streptococcus_phage	1.2e-39	98.7
WP_001177094.1\|564809_565163_+	helix-turn-helix transcriptional regulator	A0A1S5SCQ5	Streptococcus_phage	1.4e-63	100.0
WP_000516820.1\|565144_565609_+	hypothetical protein	A0A1S5SCN9	Streptococcus_phage	4.9e-85	100.0
WP_001028147.1\|565717_566260_+\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	9.8e-101	100.0
WP_000143215.1\|566689_567007_+	HNH endonuclease	A0A1S5SD32	Streptococcus_phage	1.5e-56	100.0
WP_054387340.1\|567143_567638_+	hypothetical protein	A0A1S5SCZ6	Streptococcus_phage	2.8e-78	97.5
WP_075275080.1\|567963_569343_+\|terminase	terminase	A0A1S5SCM6	Streptococcus_phage	2.1e-272	99.8
WP_075275078.1\|569495_570494_+\|portal	phage portal protein	A0A1S5SCP3	Streptococcus_phage	1.8e-188	99.7
WP_000413203.1\|570540_571083_+\|head,protease	HK97 family phage prohead protease	A0A1S5SCT6	Streptococcus_phage	1.2e-98	100.0
WP_000855224.1\|571097_572351_+\|capsid	phage capsid protein	A0A1S5SCZ2	Streptococcus_phage	4.4e-229	100.0
WP_000154006.1\|572376_572712_+	hypothetical protein	A0A1S5SCM7	Streptococcus_phage	4.1e-57	100.0
WP_000842790.1\|572708_573014_+\|head,tail	head-tail adaptor protein	A0A1S5SCR5	Streptococcus_phage	9.5e-37	100.0
WP_001074487.1\|573013_573361_+	hypothetical protein	A0A1S5SCP8	Streptococcus_phage	3.5e-59	100.0
WP_000534621.1\|573347_573692_+	hypothetical protein	A0A1S5SCM8	Streptococcus_phage	1.2e-59	100.0
WP_000221469.1\|573705_574374_+	hypothetical protein	A0A1S5SD39	Streptococcus_phage	7.0e-125	100.0
WP_000591561.1\|574375_574852_+	hypothetical protein	A0A1S5SD04	Streptococcus_phage	7.8e-86	100.0
WP_000852167.1\|575038_577777_+\|tail	phage tail tape measure protein	A0A1S5SD82	Streptococcus_phage	0.0e+00	100.0
WP_050199190.1\|577773_578496_+\|tail	phage tail protein	A0A1S5SD49	Streptococcus_phage	6.2e-135	99.6
WP_114880801.1\|578496_586458_+	peptidase S74	A0A141E0W6	Streptococcus_phage	0.0e+00	88.5
WP_001091109.1\|586551_586755_+	hypothetical protein	A0A060QN53	Streptococcus_phage	1.3e-26	100.0
WP_000852248.1\|586757_587108_+	hypothetical protein	A0A1S5SCG9	Streptococcus_phage	4.7e-64	100.0
WP_001165341.1\|587117_587534_+\|holin	holin	A0A1S5SFD4	Streptococcus_phage	2.4e-67	100.0
WP_001186207.1\|587537_587870_+\|holin	phage holin	A0A1S5SAT2	Streptococcus_phage	2.5e-51	100.0
WP_000350489.1\|587873_588830_+	N-acetylmuramoyl-L-alanine amidase family protein	A0A1S5SB92	Streptococcus_phage	1.3e-145	100.0
WP_001233269.1\|589098_589278_-	hypothetical protein	Q3BLW4	Phage_SK137	2.1e-23	96.6
WP_162489709.1\|589419_589569_-	hypothetical protein	C5J952	Streptococcus_phage	4.5e-16	93.9
WP_000291874.1\|589838_590306_+	nucleoside deaminase	NA	NA	NA	NA
589733:589753	attR	NA	NA	NA	NA
WP_000701992.1\|590492_590936_+	dUTP diphosphatase	Q2WG49	Clostridium_botulinum_D_phage	2.1e-29	47.3
WP_000691236.1\|590937_591453_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_074017595.1\|591466_592828_+	DNA repair protein RadA	NA	NA	NA	NA
WP_001809263.1\|592900_593398_+	carbonic anhydrase	NA	NA	NA	NA
WP_001827117.1\|593613_594237_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_000010163.1\|594381_595350_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	4.0e-44	34.7
WP_050208543.1\|595467_595821_+	ribose-phosphate pyrophosphokinase	NA	NA	NA	NA
WP_001866636.1\|596143_596413_+	hypothetical protein	NA	NA	NA	NA
WP_050279195.1\|596915_599549_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	1.3e-57	30.1
WP_000076479.1\|599633_600071_+	CoA-binding protein	NA	NA	NA	NA
WP_000009175.1\|600478_601489_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_000366348.1\|601637_602807_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_050220959.1\|602803_603574_+	DNA repair protein RecO	NA	NA	NA	NA
WP_000717456.1\|603570_604563_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_000136447.1\|604568_604802_+	acyl carrier protein	A0A2I7RIC8	Vibrio_phage	3.3e-05	40.6
WP_001093487.1\|605340_605571_+\|bacteriocin	bacteriocin-like peptide BlpU	NA	NA	NA	NA
WP_050221223.1\|607699_609853_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	3.6e-45	28.2
WP_000801629.1\|609865_611215_+	HlyD family secretion protein	NA	NA	NA	NA
WP_000043313.1\|611384_612092_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	1.3e-41	39.2
WP_114880802.1\|612293_616019_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.3e-37	25.8
WP_050104961.1\|616111_617554_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.4e-55	35.4
WP_114880803.1\|617590_618613_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	3.6e-64	43.6
WP_000717506.1\|618609_619155_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.4e-24	35.0

DBSCAN-SWA_3

828552 : 951171

115

Streptococcus_phage(15.0%)

protease,tRNA,transposase,holin,integrase

attL 820214:820244|attR 927507:927522

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
820214:820244	attL	NA	NA	NA	NA
WP_000660459.1\|828552_829260_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
820214:820244	attL	NA	NA	NA	NA
WP_054387354.1\|829352_830327_+	dihydropteroate synthase	NA	NA	NA	NA
WP_050086614.1\|830328_831639_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000375848.1\|831631_832186_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.7e-39	43.8
WP_000372536.1\|832228_833041_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_000886031.1\|833085_833403_-	DUF960 domain-containing protein	NA	NA	NA	NA
WP_001044624.1\|833759_834206_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000075973.1\|834225_834618_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_000199095.1\|836776_837247_-	hypothetical protein	NA	NA	NA	NA
WP_000370602.1\|837243_838134_-	hypothetical protein	NA	NA	NA	NA
WP_050102738.1\|838336_839548_+	hypothetical protein	NA	NA	NA	NA
WP_029658590.1\|840102_840504_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001106634.1\|840879_842088_-	ATP-binding protein	NA	NA	NA	NA
WP_050220972.1\|843069_845283_+	alpha-xylosidase	NA	NA	NA	NA
WP_000203056.1\|845504_845981_-	glutathione peroxidase	NA	NA	NA	NA
WP_050084637.1\|846203_849404_+	LPXTG-anchored hyaluronate lyase	NA	NA	NA	NA
WP_000167295.1\|850549_851179_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_000161488.1\|851188_852190_-	sugar kinase	NA	NA	NA	NA
WP_000684783.1\|852220_852862_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_000185881.1\|852880_853696_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_000706826.1\|853966_854401_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000592942.1\|854412_855603_+	unsaturated chondroitin disaccharide hydrolase	NA	NA	NA	NA
WP_000178623.1\|855613_856105_+	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_000026610.1\|856119_856899_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_114880809.1\|856885_857704_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_000381739.1\|857703_857997_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_000657076.1\|858018_859920_+	alginate lyase family protein	NA	NA	NA	NA
WP_000412453.1\|859979_860981_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000838117.1\|861090_861426_-	hypothetical protein	NA	NA	NA	NA
WP_000711819.1\|861436_861679_-	hypothetical protein	NA	NA	NA	NA
WP_001082474.1\|861694_861889_-	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	7.2e-06	42.6
WP_000159408.1\|862054_863005_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_000840840.1\|863016_863334_+	cell division protein FtsL	NA	NA	NA	NA
WP_050226568.1\|863337_865590_+	PASTA domain-containing protein	NA	NA	NA	NA
WP_000470820.1\|865591_866572_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_050087995.1\|867120_869226_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.0e-116	37.5
866798:866828	attR	NA	NA	NA	NA
WP_000032550.1\|869521_870004_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
866798:866828	attR	NA	NA	NA	NA
WP_000743574.1\|870098_871583_-	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_001156854.1\|871735_873346_+	alpha-glucosidase	NA	NA	NA	NA
WP_114880810.1\|873476_874907_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_000091070.1\|875062_876508_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	4.7e-134	60.1
WP_000565348.1\|876509_877241_+	tyrosine-protein phosphatase CpsB	NA	NA	NA	NA
WP_000664166.1\|877249_877942_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	4.3e-61	55.9
WP_114880811.1\|877951_878635_+	polysaccharide biosynthesis tyrosine autokinase CpsD	A0A1X9I5D6	Streptococcus_phage	6.6e-70	60.9
WP_000343586.1\|878650_880018_+	sugar transferase	NA	NA	NA	NA
WP_001205627.1\|880021_880765_+	WecB/TagA/CpsF family glycosyltransferase	NA	NA	NA	NA
WP_001076784.1\|880761_881586_+\|holin	LPS cholinephosphotransferase	A0A1V0SD50	Indivirus	1.3e-06	27.7
WP_000458863.1\|881587_882466_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000120848.1\|882466_883804_+	oligosaccharide repeat unit polymerase	NA	NA	NA	NA
WP_001092839.1\|883826_885248_+	hypothetical protein	NA	NA	NA	NA
WP_000723326.1\|885311_886400_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.0e-27	30.3
WP_000676141.1\|886438_887308_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	2.0e-100	62.8
WP_000131456.1\|887308_887905_+	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.9e-10	33.1
WP_000141499.1\|887914_888964_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.3e-72	44.5
WP_000600901.1\|889029_889881_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.5e-26	35.0
WP_025169503.1\|889977_890391_+\|transposase	transposase	A0A218MNE7	uncultured_virus	9.0e-06	24.6
WP_000245755.1\|890463_890721_+\|transposase	transposase	NA	NA	NA	NA
WP_050239038.1\|890766_890913_+\|transposase	transposase	NA	NA	NA	NA
WP_001811052.1\|890983_891142_+	hypothetical protein	NA	NA	NA	NA
WP_000842609.1\|891340_893323_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_114880812.1\|893622_898950_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_054387366.1\|899116_901276_-	penicillin-binding protein 1A	NA	NA	NA	NA
WP_000248787.1\|901272_901869_-	Holliday junction resolvase RecU	A0A1L2JY30	Aeribacillus_phage	8.7e-18	33.9
WP_000179555.1\|901934_902462_+	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_000146522.1\|902531_902861_+	cell division regulator GpsB	NA	NA	NA	NA
WP_000711391.1\|903346_904504_+	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_000039276.1\|904516_905911_+	mid-cell-anchored protein MapZ	NA	NA	NA	NA
WP_000158781.1\|905986_907411_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	1.6e-41	29.6
WP_000518016.1\|907422_908112_+	response regulator transcription factor	NA	NA	NA	NA
WP_000771105.1\|908209_909175_+\|holin	choline-binding protein CbpC	NA	NA	NA	NA
WP_000771134.1\|909193_910192_+\|holin	choline-binding protein CbpJ	NA	NA	NA	NA
WP_000765664.1\|910309_911542_-	MFS transporter	NA	NA	NA	NA
WP_001820155.1\|912070_912409_-	lantibiotic-modifying protein	NA	NA	NA	NA
WP_000163323.1\|913524_914403_+	mevalonate kinase	NA	NA	NA	NA
WP_114880813.1\|914384_915338_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_000562419.1\|915324_916332_+	phosphomevalonate kinase	NA	NA	NA	NA
WP_000210629.1\|916315_917326_+	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_001224634.1\|917403_918102_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_000743661.1\|918098_919094_+	sensor histidine kinase	NA	NA	NA	NA
WP_000698432.1\|919107_919740_+	response regulator transcription factor	NA	NA	NA	NA
WP_078746734.1\|919896_920208_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_000754501.1\|920648_920888_+	hypothetical protein	NA	NA	NA	NA
WP_050221163.1\|920968_921790_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_050221162.1\|921808_922831_+\|holin	choline-binding protein CbpF	NA	NA	NA	NA
WP_078133068.1\|923116_923509_+\|integrase	tyrosine-type recombinase/integrase	C9E2L6	Enterococcus_phage	4.7e-20	41.4
WP_050221161.1\|923669_924953_+	trigger factor	NA	NA	NA	NA
WP_050221160.1\|925000_927367_-	ATP-dependent RecD-like DNA helicase	A0A0K2FLP8	Brevibacillus_phage	5.3e-58	27.2
WP_001815645.1\|927443_927566_-	hypothetical protein	NA	NA	NA	NA
WP_001083986.1\|927645_928260_-	signal peptidase I	NA	NA	NA	NA
WP_050199411.1\|928263_929145_-	ribonuclease HIII	NA	NA	NA	NA
WP_000002019.1\|929231_929534_+	cell division protein ZapA	NA	NA	NA	NA
WP_000622953.1\|929530_930079_+	CvpA family protein	NA	NA	NA	NA
WP_050199407.1\|930182_932519_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.3e-21	55.1
WP_114880814.1\|932861_934184_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_000206761.1\|934401_934950_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_000735969.1\|935059_935959_+	TDT family transporter	NA	NA	NA	NA
WP_000884253.1\|935983_937258_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.5e-91	48.7
WP_000079355.1\|937471_937843_-	DUF956 family protein	NA	NA	NA	NA
WP_000869675.1\|937845_939210_-	aspartate kinase	NA	NA	NA	NA
WP_000400073.1\|939534_940320_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_000386347.1\|940413_940848_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000852956.1\|940847_941822_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_000257841.1\|941881_942106_+	acyl carrier protein	NA	NA	NA	NA
WP_000857426.1\|942224_943199_+	enoyl-[acyl-carrier-protein] reductase FabK	NA	NA	NA	NA
WP_000167622.1\|943191_944112_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_000763053.1\|944145_944877_+	3-oxoacyl-[acyl-carrier-protein] reductase	F2NZ40	Diadromus_pulchellus_ascovirus	2.2e-15	30.9
WP_000774063.1\|944898_946134_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_001052243.1\|946136_946622_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_000565514.1\|946618_947041_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_000488675.1\|947052_948420_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_001173353.1\|948456_949323_+	acetyl-CoA carboxylase carboxyltransferase subunit beta	NA	NA	NA	NA
WP_001017398.1\|949319_950087_+	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_000148169.1\|950245_950431_+	biofilm-regulating peptide BriC	NA	NA	NA	NA
WP_001246429.1\|950448_950922_+	hypothetical protein	NA	NA	NA	NA
WP_001810355.1\|950934_951171_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_4

1396781 : 1404931

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044789102.1\|1396781_1398665_+	MBL fold metallo-hydrolase	Q332B9	Clostridium_botulinum_C_phage	3.3e-10	23.7
WP_074017610.1\|1398744_1399875_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.9e-114	58.4
WP_000254676.1\|1399884_1401147_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	4.2e-139	64.3
WP_000689706.1\|1401150_1401948_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	8.0e-59	50.2
WP_000033362.1\|1402167_1402806_+	dTMP kinase	M1PSC7	Streptococcus_phage	9.8e-76	68.1
WP_000806706.1\|1402802_1403693_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.4e-72	51.4
WP_000358228.1\|1403732_1404050_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_050221186.1\|1404052_1404931_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.6e-115	75.4

DBSCAN-SWA_5

1858364 : 1865381

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025173657.1\|1858364_1859081_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	2.3e-25	31.1
WP_001272941.1\|1859603_1860215_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_001864597.1\|1860259_1860988_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272304.1\|1861026_1861938_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.0e-89	51.5
WP_000926599.1\|1862003_1862228_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590986.1\|1862305_1863049_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-29	41.0
WP_001103449.1\|1863048_1863849_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_001864599.1\|1864006_1864363_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	3.3e-33	56.4
WP_001170347.1\|1864356_1864887_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.4e-46	54.3
WP_001864601.1\|1864886_1865381_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.1e-42	52.1

DBSCAN-SWA_6

1962651 : 1969405

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000081003.1\|1962651_1963620_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
WP_000011276.1\|1963653_1964565_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.3e-155	100.0
WP_001231086.1\|1964561_1965539_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
WP_000163033.1\|1965535_1966426_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.9e-06	29.8
WP_001140412.1\|1966477_1966858_-	RidA family protein	NA	NA	NA	NA
WP_000422599.1\|1966868_1967456_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_000106346.1\|1967464_1968697_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.2e-131	59.0
WP_000162486.1\|1968898_1969405_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	2.3e-27	43.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP031245

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection