CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022909	Staphylococcus aureus strain 545 plasmid pPS00078.1A.1, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_CP022908	Staphylococcus aureus strain 545 chromosome, complete genome	12 crisprs	cas3,DEDDh,DinG,csa3,WYL	11	6	14	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022908_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_1

46225-46335

Orphan

Consensus_repeat	Method
TATAAGGACTTAAATTATAAAACGTCCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_1

>merge|NZ_CP022908|1|46225-46335|CRISPRCasFinder
TATAAGGACTTAAATTATAAAACGTCCCTCTATAATAACTAACGAAAGAATTATAACACCTATTATATAGAGAATAAAGTTTATAAGTGACTTAAATTATAAAACGTCCCT

>NZ_CP022908|1|1|46225-46335|CRISPRCasFinder
TATAAGGACTTAAATTATAAAACGTCCCT	CTATAATAACTAACGAAAGAATTATAACACCTATTATATAGAGAATAAAGTTT
ATAAGTGACTTAAATTATAAAACGTCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_020444595.1\|36516_36906_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NZ_CP022908.1\|WP_115276558.1\|49626_50427_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224596
NZ_CP022908.1\|WP_002485398.1\|48420_48618_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001106022.1\|52470_53145_+\|IS6-like-element-IS257-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP022908.1\|WP_115276553.1\|42120_42378_+\|DUF3387-domain-containing-protein	unknown	unknown	gnl\|CDD\|378743
NZ_CP022908.1\|WP_001549960.1\|41162_42149_+\|beta-lactam-sensor/signal-transducer-MecR1	unknown	unknown	gnl\|CDD\|226672
NZ_CP022908.1\|WP_115276555.1\|44551_44710_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368760
NZ_CP022908.1\|WP_115276559.1\|54711_55254_-\|streptothricin-N-acetyltransferase-Sat4	unknown	unknown	gnl\|CDD\|366181
NZ_CP022908.1\|WP_000872606.1\|38582_39011_+\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239538
NZ_CP022908.1\|WP_053522978.1\|50522_50729_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_115276557.1\|48593_48983_-\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576
NZ_CP022908.1\|WP_049325240.1\|47423_48434_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NZ_CP022908.1\|WP_063852655.1\|39056_41066_-\|PBP2a-family-beta-lactam-resistant-peptidoglycan-transpeptidase-MecA	unknown	unknown	gnl\|CDD\|223839
NZ_CP022908.1\|WP_162797737.1\|44030_44537_-\|DUF1643-domain-containing-protein	unknown	unknown	gnl\|CDD\|226783
NZ_CP022908.1\|WP_002485551.1\|49251_49530_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001096887.1\|53824_54619_-\|aminoglycoside-O-phosphotransferase-APH(3')-IIIa	unknown	unknown	gnl\|CDD\|270699
NZ_CP022908.1\|WP_080351733.1\|46915_47362_-\|DUF334-domain-containing-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001106022.1\|44756_45431_-\|IS6-like-element-IS257-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP022908.1\|WP_000958858.1\|37742_38486_+\|glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176505
NZ_CP022908.1\|WP_115276556.1\|45460_46204_-\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|227814

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_020444595.1\|36516_36906_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	1.1047e-39
NZ_CP022908.1\|WP_115276558.1\|49626_50427_-\|ABC-transporter-permease	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	5.01664e-39
NZ_CP022908.1\|WP_001106022.1\|52470_53145_+\|IS6-like-element-IS257-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.63523e-85
NZ_CP022908.1\|WP_115276553.1\|42120_42378_+\|DUF3387-domain-containing-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	1.37468e-32
NZ_CP022908.1\|WP_001549960.1\|41162_42149_+\|beta-lactam-sensor/signal-transducer-MecR1	gnl\|CDD\|226672	COG4219, MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms].	1.47485e-138
NZ_CP022908.1\|WP_115276555.1\|44551_44710_-\|hypothetical-protein	gnl\|CDD\|368760	pfam06124, DUF960, Staphylococcal protein of unknown function (DUF960). This family consists of several hypothetical proteins from several species of Staphylococcus. The function of this family is unknown.	2.3275e-06
NZ_CP022908.1\|WP_115276559.1\|54711_55254_-\|streptothricin-N-acetyltransferase-Sat4	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.19335e-21
NZ_CP022908.1\|WP_000872606.1\|38582_39011_+\|MaoC-family-dehydratase	gnl\|CDD\|239538	cd03454, YdeM, YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	1.10823e-65
NZ_CP022908.1\|WP_115276557.1\|48593_48983_-\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.000876526
NZ_CP022908.1\|WP_049325240.1\|47423_48434_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	4.96368e-84
NZ_CP022908.1\|WP_063852655.1\|39056_41066_-\|PBP2a-family-beta-lactam-resistant-peptidoglycan-transpeptidase-MecA	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	5.1524e-100
NZ_CP022908.1\|WP_162797737.1\|44030_44537_-\|DUF1643-domain-containing-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.03252e-77
NZ_CP022908.1\|WP_001096887.1\|53824_54619_-\|aminoglycoside-O-phosphotransferase-APH(3')-IIIa	gnl\|CDD\|270699	cd05150, APH, Aminoglycoside 3'-phosphotransferase. APH catalyzes the transfer of the gamma-phosphoryl group from ATP to aminoglycoside antibiotics such as kanamycin, streptomycin, neomycin, and gentamicin, among others. The aminoglycoside antibiotics target the 30S ribosome and promote miscoding, leading to the production of defective proteins which insert into the bacterial membrane, resulting in membrane damage and the ultimate demise of the bacterium. Phosphorylation of the aminoglycoside antibiotics results in their inactivation, leading to bacterial antibiotic resistance. The APH gene is found on transposons and plasmids and is thought to have originated as a self-defense mechanism used by microorganisms that produce the antibiotics. The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	7.26961e-101
NZ_CP022908.1\|WP_001106022.1\|44756_45431_-\|IS6-like-element-IS257-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.63523e-85
NZ_CP022908.1\|WP_000958858.1\|37742_38486_+\|glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176505	cd08562, GDPD_EcUgpQ_like, Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46), UgpQ, and similar proteins. GP-GDE plays an essential role in the metabolic pathway of E. coli. It catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols, which are major sources of carbon and phosphate. E. coli possesses two major G3P uptake systems: Glp and Ugp, which contain genes coding for two distinct GP-GDEs. UgpQ gene from the E. coli ugp operon codes for a cytosolic phosphodiesterase GlpQ, which is the prototype of this family. Various glycerophosphodiesters, such as glycerophosphocholine (GPC), glycerophosphoethanolanmine (GPE), glycerophosphoglycerol (GPG), glycerophosphoinositol (GPI), and glycerophosphoserine (GPS), can only be hydrolyzed by UgpQ during transport at the inner side of the cytoplasmic membrane to alcohols and G3P, which is a source of phosphate. In contrast to Ca2+-dependent periplasmic phosphodiesterase GlpQ, cytosolic phosphodiesterase UgpQ requires divalent cations, such as Mg2+, Co2+, or Mn2+, for its enzyme activity.	7.22645e-112
NZ_CP022908.1\|WP_115276556.1\|45460_46204_-\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|227814	COG5527, COG5527, Protein involved in initiation of plasmid replication [DNA replication, recombination, and repair].	5.08439e-67

>NZ_CP022908.1|WP_115276556.1|45460_46204_-|RepB-family-plasmid-replication-initiator-protein
MSGETVVYRNEMNLVPLRRFTSTEVDLFFTLCNKLKEQDTRKVIIPFEELKYLSNYYTRSQERFINDLEHVYDKMLNLTYVERNGRSFEKFVLFTSYKVDLDEECLSISVNPDLKHILNSITADFTKFELKEMTHLKSTYAKNMFRLLKQYKHTGYVKINIADFRNRLDIPKTYQMNDITKRVLKPIINELSSIFNNLNINKIKAKKGRKIECLEFTFDAEKRIHSKRQPQMANIGKSRGSVAKLNL
>NZ_CP022908.1|WP_001106022.1|44756_45431_-|IS6-like-element-IS257-family-transposase
MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRGRGVNVHHSTVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
>NZ_CP022908.1|WP_115276555.1|44551_44710_-|hypothetical-protein
MQQNQQEQPTYKLEYHYTNYEKNQNALPKKVYVIREDDVDAFYYVMLLPEEY
>NZ_CP022908.1|WP_162797737.1|44030_44537_-|DUF1643-domain-containing-protein
MNTIKSTIHTEAIFSDDEQHRYLLKKTWDEKKPACTVITMYPHLDGVLSLDLTTVLILNQLANTEQYGAVYLVNLFSNIRTPENLKHIKNPYDEHTDIHLMKAISESDTVILAYGAYAKRPVVIDRVEQVMEMLKPHKKKVKKLINPVTNEIMHPLNPKARQKWILKS
>NZ_CP022908.1|WP_115276553.1|42120_42378_+|DUF3387-domain-containing-protein
MYVVYRASHETAKEALGDKELRAIAHELTKTVKDNMSVDWSKRDSAKAKMRVQVRRLLKKYGYPPDLQKMAVEQVVEQAELMASQ
>NZ_CP022908.1|WP_001549960.1|41162_42149_+|beta-lactam-sensor/signal-transducer-MecR1
MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVLVSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFETSNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKKHITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQLYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKSQHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISSFT
>NZ_CP022908.1|WP_063852655.1|39056_41066_-|PBP2a-family-beta-lactam-resistant-peptidoglycan-transpeptidase-MecA
MMKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEVEMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYLSDFAKKFHLTTNETESRNYPLEKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFEKGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISKENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENGNKKYDIDE
>NZ_CP022908.1|WP_000872606.1|38582_39011_+|MaoC-family-dehydratase
MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAEQSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAEITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS
>NZ_CP022908.1|WP_000958858.1|37742_38486_+|glycerophosphoryl-diester-phosphodiesterase
MLTVYGHRGLPSKAPENTIASFKAASEVEGINWLELDVAITKDEQLIIIHDDYLERTTNMSGEITELNYDEIKDASAGSWFGEKFKDEHLPTFDDVVKIANEYNMNLNVELKGITGPNGLALSKSMVKQVEEQLTNLNQNQEVLISSFNVVLVKLAEEIMPQYNRAVIFHTTSFREDWRTLLDYCNAKIVNTEDAKLTKAKVKMVKEAGYELNVWTVNKPARANQLANWGVDGIFTDNADKMVHLSQ
>NZ_CP022908.1|WP_020444595.1|36516_36906_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MQLCNRTVLWNRDVGNIYTGSLYLSLISLLQNHTFQPEEKVCLFSYGSGAVGEIFSGSIVKGYDKALDKEKHLNMLESREQLSVEEYETFFNRFDNQEFDFERELTQDPYSKVYLYSIEDHIRTYKIEK
>NZ_CP022908.1|WP_080351733.1|46915_47362_-|DUF334-domain-containing-protein
MNNDNLKQDFQTAIQEELEDVKTDTHKAIEQLQTNQSELRQANNDYKKMIDERIKHNDIAMKQYDQALNRLTQGITAMFFIIALVMVAFLVLSPLGDWLGVQNFYEWLNHVLKTSHSTWRYLMIVFYLVPYALFGLLIYAILSAYKRI
>NZ_CP022908.1|WP_049325240.1|47423_48434_-|relaxase/mobilization-nuclease-domain-containing-protein
MATTKLSATKSTSRAINYAEKRAVEKSGLNCDVDYAKSNFKAARELYGKTDGNQGHVIIQSFKPGEVTPEQCNQLGLALAEKLAPNHQVAVYTHADTDHVHNHIVINAINLETGKKFNNNKQALRDVRDFNDVVCREHGLSVPEKDTARLRYTQTEKAIADPNTQSTVQYSWKDEIREAIDQSQATNMDEFKDHLNQHGITIERVTPKSITYRHLAEDKKVRGRKLGEDYNKGGIEDGFERQIQRQQQTERASDTDVQPKRRTSSRDEETERDTGVTQSDWDKFAQDTNELERSRQAAESARLVDEKARRDREERARAKQASQRIINDDRDHGLEL
>NZ_CP022908.1|WP_002485398.1|48420_48618_-|hypothetical-protein
MENTKGTMIVSAVLLVVCLAIASFLIFHEQQIFPSLIFLGLAFIDGTKFYLSYQKLKERDHHGDN
>NZ_CP022908.1|WP_115276557.1|48593_48983_-|plasmid-mobilization-relaxosome-protein-MobC
MSEQNTFVASDETVGRNRKPNRKAPKQISFRVSESEYLKLQQSAETLNMSVPAFVKKKAQGARLVAPKLDKATRQSVAKDLSMLGANANQIAKYCNQHQHEAPNYEALERNISELREMLDEIWKTLKEQ
>NZ_CP022908.1|WP_002485551.1|49251_49530_-|hypothetical-protein
MLLRETEDYEKYYKIGNVVMGTAFICIVIFSLMKSTPLPDLSFLKYIHFASEVLLIAGLIINSVPDFLTWNIKNIIFDLIIISFLIVFFIWV
>NZ_CP022908.1|WP_115276558.1|49626_50427_-|ABC-transporter-permease
MKSSLFILKEHFNNLYLMKRLAQFEMKISNKNNYLGTAWELINPSIQIFMYWFIFGLGFRNNRTVENIPFIFWLIVGISMWFFVNQGILNGTKAVTSKYKQVAKMNFPLSILSSYIVLSKFYTHVLLLILIMLICALNGYYPTIYTLQLLIFIPYTLLLTMTIALLTSTLAVIIRDVQMLMQALMRIIFFISSILYLPTNTLVLKVIQFNPIYFITESYRAAILYQNWFFITHWKLSLYNLAFLLITFVLGSLLHVKYREQFADFL
>NZ_CP022908.1|WP_053522978.1|50522_50729_-|hypothetical-protein
MRGRNEKISKLLIAFSLVTTLSYASASTGFMNDNSHEAFAKSKKKKHKGNGNKHNCFPVGNSEFCTTP
>NZ_CP022908.1|WP_001106022.1|52470_53145_+|IS6-like-element-IS257-family-transposase
MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRGRGVNVHHSTVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
>NZ_CP022908.1|WP_001096887.1|53824_54619_-|aminoglycoside-O-phosphotransferase-APH(3')-IIIa
MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYEDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF
>NZ_CP022908.1|WP_115276559.1|54711_55254_-|streptothricin-N-acetyltransferase-Sat4
MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAPYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDIAVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDTMLYPNFENNFEKAVFWYLRF

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Crispr_ID: NZ_CP022908_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_2

417390-417490

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_2

>merge|NZ_CP022908|2|417390-417490|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NZ_CP022908|2|2|417390-417490|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000264071.1\|422189_423656_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP022908.1\|WP_000763768.1\|419385_419793_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP022908.1\|WP_000793009.1\|420883_422152_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP022908.1\|WP_000956132.1\|417506_418463_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_CP022908.1\|WP_000991007.1\|415141_416530_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP022908.1\|WP_000158374.1\|409349_409931_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP022908.1\|WP_000421410.1\|420305_420884_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP022908.1\|WP_000424966.1\|423680_425222_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP022908.1\|WP_000551776.1\|425334_425871_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000394698.1\|418580_419243_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000211676.1\|408962_409172_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001789518.1\|416614_416716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000746687.1\|410634_411261_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP022908.1\|WP_000041883.1\|426263_426968_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP022908.1\|WP_000159787.1\|427366_427639_-\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP022908.1\|WP_000052781.1\|413244_413814_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP022908.1\|WP_001795623.1\|411333_411627_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000930486.1\|411705_413229_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP022908.1\|WP_000868248.1\|409996_410380_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001289311.1\|414305_415061_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000264071.1\|422189_423656_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP022908.1\|WP_000763768.1\|419385_419793_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
NZ_CP022908.1\|WP_000793009.1\|420883_422152_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
NZ_CP022908.1\|WP_000956132.1\|417506_418463_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
NZ_CP022908.1\|WP_000991007.1\|415141_416530_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP022908.1\|WP_000158374.1\|409349_409931_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
NZ_CP022908.1\|WP_000421410.1\|420305_420884_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NZ_CP022908.1\|WP_000424966.1\|423680_425222_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP022908.1\|WP_000746687.1\|410634_411261_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
NZ_CP022908.1\|WP_000041883.1\|426263_426968_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
NZ_CP022908.1\|WP_000159787.1\|427366_427639_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NZ_CP022908.1\|WP_000052781.1\|413244_413814_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NZ_CP022908.1\|WP_000930486.1\|411705_413229_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP022908.1\|WP_001289311.1\|414305_415061_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88

>NZ_CP022908.1|WP_001789518.1|416614_416716_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>NZ_CP022908.1|WP_000991007.1|415141_416530_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>NZ_CP022908.1|WP_001289311.1|414305_415061_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP022908.1|WP_000052781.1|413244_413814_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP022908.1|WP_000930486.1|411705_413229_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP022908.1|WP_001795623.1|411333_411627_-|hypothetical-protein
MINLIYTTRCAIMLKVCTSRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLVQPIMQLFIDKAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>NZ_CP022908.1|WP_000746687.1|410634_411261_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP022908.1|WP_000868248.1|409996_410380_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>NZ_CP022908.1|WP_000158374.1|409349_409931_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>NZ_CP022908.1|WP_000211676.1|408962_409172_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFNPILSTFSNIIIHIDHFHANKKDDN
>NZ_CP022908.1|WP_000956132.1|417506_418463_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP022908.1|WP_000394698.1|418580_419243_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP022908.1|WP_000763768.1|419385_419793_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>NZ_CP022908.1|WP_000421410.1|420305_420884_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_CP022908.1|WP_000793009.1|420883_422152_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP022908.1|WP_000264071.1|422189_423656_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP022908.1|WP_000424966.1|423680_425222_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP022908.1|WP_000551776.1|425334_425871_-|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NZ_CP022908.1|WP_000041883.1|426263_426968_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NZ_CP022908.1|WP_000159787.1|427366_427639_-|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Crispr_ID: NZ_CP022908_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_3

657916-658008

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_3

>merge|NZ_CP022908|3|657916-658008|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>NZ_CP022908|3|3|657916-658008|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000655099.1\|654400_654508_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000365354.1\|660116_660836_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP022908.1\|WP_000735558.1\|661755_662262_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001200748.1\|653315_654326_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP022908.1\|WP_115276595.1\|655013_656675_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP022908.1\|WP_000169042.1\|666793_667018_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP022908.1\|WP_000362967.1\|660819_661620_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP022908.1\|WP_000633782.1\|649751_650288_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP022908.1\|WP_001018677.1\|664347_664722_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP022908.1\|WP_001790232.1\|659111_660062_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP022908.1\|WP_000477504.1\|650456_650933_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP022908.1\|WP_000808902.1\|648602_649541_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP022908.1\|WP_001788287.1\|652295_652817_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP022908.1\|WP_001553862.1\|665669_666599_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP022908.1\|WP_001045421.1\|663308_664097_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP022908.1\|WP_001819741.1\|654633_655017_+\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP022908.1\|WP_001222133.1\|662423_663140_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000180230.1\|650972_652268_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP022908.1\|WP_000901764.1\|657062_657698_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP022908.1\|WP_001813976.1\|658136_658964_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000365354.1\|660116_660836_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP022908.1\|WP_001200748.1\|653315_654326_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP022908.1\|WP_115276595.1\|655013_656675_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP022908.1\|WP_000169042.1\|666793_667018_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NZ_CP022908.1\|WP_000362967.1\|660819_661620_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
NZ_CP022908.1\|WP_000633782.1\|649751_650288_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NZ_CP022908.1\|WP_001018677.1\|664347_664722_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP022908.1\|WP_001790232.1\|659111_660062_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_CP022908.1\|WP_000477504.1\|650456_650933_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP022908.1\|WP_000808902.1\|648602_649541_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_CP022908.1\|WP_001788287.1\|652295_652817_+\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP022908.1\|WP_001553862.1\|665669_666599_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37
NZ_CP022908.1\|WP_001045421.1\|663308_664097_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
NZ_CP022908.1\|WP_001819741.1\|654633_655017_+\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
NZ_CP022908.1\|WP_000180230.1\|650972_652268_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP022908.1\|WP_000901764.1\|657062_657698_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_CP022908.1\|WP_001813976.1\|658136_658964_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.32108e-72

>NZ_CP022908.1|WP_000901764.1|657062_657698_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP022908.1|WP_115276595.1|655013_656675_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEVRLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP022908.1|WP_001819741.1|654633_655017_+|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP022908.1|WP_000655099.1|654400_654508_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NZ_CP022908.1|WP_001200748.1|653315_654326_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP022908.1|WP_001788287.1|652295_652817_+|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP022908.1|WP_000180230.1|650972_652268_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP022908.1|WP_000477504.1|650456_650933_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP022908.1|WP_000633782.1|649751_650288_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP022908.1|WP_000808902.1|648602_649541_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NZ_CP022908.1|WP_001813976.1|658136_658964_+|ABC-transporter-substrate-binding-protein
MKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP022908.1|WP_001790232.1|659111_660062_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP022908.1|WP_000365354.1|660116_660836_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP022908.1|WP_000362967.1|660819_661620_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP022908.1|WP_000735558.1|661755_662262_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP022908.1|WP_001222133.1|662423_663140_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP022908.1|WP_001045421.1|663308_664097_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NZ_CP022908.1|WP_001018677.1|664347_664722_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP022908.1|WP_001553862.1|665669_666599_-|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP022908.1|WP_000169042.1|666793_667018_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: NZ_CP022908_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_4

816307-816387

Unclear

Consensus_repeat	Method
TTCTTTATGTTGGGGCCCCGCCAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_4

>merge|NZ_CP022908|4|816307-816387|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTAGAATTTCTTTTCGAAATTCTTTATGTTGGGGCCCCGCCAACT

>NZ_CP022908|4|4|816307-816387|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACT	TGCATTGTTTGTAGAATTTCTTTTCGAAA
TTCTTTATGTTGGGGCCCCGCCAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000816295.1\|826524_827427_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP022908.1\|WP_000134963.1\|820407_821343_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP022908.1\|WP_000057548.1\|818901_820341_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP022908.1\|WP_000662681.1\|813170_816017_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP022908.1\|WP_000506531.1\|804647_807179_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP022908.1\|WP_010956549.1\|807493_808604_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP022908.1\|WP_000638419.1\|810672_810909_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP022908.1\|WP_000617735.1\|803661_804234_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP022908.1\|WP_000006551.1\|824177_825122_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP022908.1\|WP_000958224.1\|816623_817556_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP022908.1\|WP_000369722.1\|822164_823076_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP022908.1\|WP_000513308.1\|817561_818401_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP022908.1\|WP_001248939.1\|823072_824068_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP022908.1\|WP_000749380.1\|809012_809852_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP022908.1\|WP_000538141.1\|810025_810676_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP022908.1\|WP_001790093.1\|808757_808865_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001790092.1\|807220_807325_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001224793.1\|818408_818894_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP022908.1\|WP_000229253.1\|811177_813163_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP022908.1\|WP_001049165.1\|825694_826282_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000816295.1\|826524_827427_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NZ_CP022908.1\|WP_000134963.1\|820407_821343_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP022908.1\|WP_000057548.1\|818901_820341_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.50708e-06
NZ_CP022908.1\|WP_000662681.1\|813170_816017_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP022908.1\|WP_000506531.1\|804647_807179_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP022908.1\|WP_010956549.1\|807493_808604_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP022908.1\|WP_000638419.1\|810672_810909_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP022908.1\|WP_000617735.1\|803661_804234_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP022908.1\|WP_000958224.1\|816623_817556_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP022908.1\|WP_000369722.1\|822164_823076_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP022908.1\|WP_000513308.1\|817561_818401_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
NZ_CP022908.1\|WP_001248939.1\|823072_824068_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP022908.1\|WP_000749380.1\|809012_809852_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NZ_CP022908.1\|WP_000538141.1\|810025_810676_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP022908.1\|WP_000006551.1\|824177_825122_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP022908.1\|WP_001224793.1\|818408_818894_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP022908.1\|WP_000229253.1\|811177_813163_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP022908.1\|WP_001049165.1\|825694_826282_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148

>NZ_CP022908.1|WP_000662681.1|813170_816017_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP022908.1|WP_000229253.1|811177_813163_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP022908.1|WP_000638419.1|810672_810909_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP022908.1|WP_000538141.1|810025_810676_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP022908.1|WP_000749380.1|809012_809852_+|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP022908.1|WP_001790093.1|808757_808865_+|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIIENVLNYMV
>NZ_CP022908.1|WP_010956549.1|807493_808604_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP022908.1|WP_001790092.1|807220_807325_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP022908.1|WP_000506531.1|804647_807179_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP022908.1|WP_000617735.1|803661_804234_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_CP022908.1|WP_000958224.1|816623_817556_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP022908.1|WP_000513308.1|817561_818401_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP022908.1|WP_001224793.1|818408_818894_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP022908.1|WP_000057548.1|818901_820341_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDRAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP022908.1|WP_000134963.1|820407_821343_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP022908.1|WP_000369722.1|822164_823076_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP022908.1|WP_001248939.1|823072_824068_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP022908.1|WP_000006551.1|824177_825122_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP022908.1|WP_001049165.1|825694_826282_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP022908.1|WP_000816295.1|826524_827427_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: NZ_CP022908_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_5

821705-821790

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_5

>merge|NZ_CP022908|5|821705-821790|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_CP022908|5|5|821705-821790|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000816295.1\|826524_827427_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP022908.1\|WP_000134963.1\|820407_821343_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP022908.1\|WP_000057548.1\|818901_820341_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP022908.1\|WP_000662681.1\|813170_816017_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP022908.1\|WP_000654030.1\|829519_830533_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP022908.1\|WP_000638419.1\|810672_810909_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP022908.1\|WP_000070826.1\|828130_828760_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP022908.1\|WP_000279414.1\|830585_831596_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP022908.1\|WP_001074749.1\|831734_832925_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP022908.1\|WP_000958224.1\|816623_817556_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP022908.1\|WP_000369722.1\|822164_823076_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP022908.1\|WP_000513308.1\|817561_818401_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP022908.1\|WP_001248939.1\|823072_824068_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP022908.1\|WP_000749380.1\|809012_809852_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP022908.1\|WP_000538141.1\|810025_810676_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP022908.1\|WP_000006551.1\|824177_825122_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP022908.1\|WP_001224793.1\|818408_818894_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP022908.1\|WP_000229253.1\|811177_813163_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP022908.1\|WP_001260089.1\|833046_833808_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP022908.1\|WP_001049165.1\|825694_826282_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000816295.1\|826524_827427_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NZ_CP022908.1\|WP_000134963.1\|820407_821343_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP022908.1\|WP_000057548.1\|818901_820341_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.50708e-06
NZ_CP022908.1\|WP_000662681.1\|813170_816017_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP022908.1\|WP_000654030.1\|829519_830533_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP022908.1\|WP_000638419.1\|810672_810909_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP022908.1\|WP_000070826.1\|828130_828760_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
NZ_CP022908.1\|WP_000279414.1\|830585_831596_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP022908.1\|WP_001074749.1\|831734_832925_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP022908.1\|WP_000958224.1\|816623_817556_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP022908.1\|WP_000369722.1\|822164_823076_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP022908.1\|WP_000513308.1\|817561_818401_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
NZ_CP022908.1\|WP_001248939.1\|823072_824068_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP022908.1\|WP_000749380.1\|809012_809852_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NZ_CP022908.1\|WP_000538141.1\|810025_810676_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP022908.1\|WP_000006551.1\|824177_825122_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP022908.1\|WP_001224793.1\|818408_818894_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP022908.1\|WP_000229253.1\|811177_813163_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP022908.1\|WP_001260089.1\|833046_833808_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NZ_CP022908.1\|WP_001049165.1\|825694_826282_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148

>NZ_CP022908.1|WP_000134963.1|820407_821343_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP022908.1|WP_000057548.1|818901_820341_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDRAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP022908.1|WP_001224793.1|818408_818894_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP022908.1|WP_000513308.1|817561_818401_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP022908.1|WP_000958224.1|816623_817556_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP022908.1|WP_000662681.1|813170_816017_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP022908.1|WP_000229253.1|811177_813163_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP022908.1|WP_000638419.1|810672_810909_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP022908.1|WP_000538141.1|810025_810676_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP022908.1|WP_000749380.1|809012_809852_+|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP022908.1|WP_000369722.1|822164_823076_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP022908.1|WP_001248939.1|823072_824068_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP022908.1|WP_000006551.1|824177_825122_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP022908.1|WP_001049165.1|825694_826282_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP022908.1|WP_000816295.1|826524_827427_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP022908.1|WP_000070826.1|828130_828760_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP022908.1|WP_000654030.1|829519_830533_+|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP022908.1|WP_000279414.1|830585_831596_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP022908.1|WP_001074749.1|831734_832925_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP022908.1|WP_001260089.1|833046_833808_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: NZ_CP022908_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_6

866309-866390

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_6

>merge|NZ_CP022908|6|866309-866390|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP022908|6|6|866309-866390|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000571218.1\|867871_868897_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP022908.1\|WP_000266157.1\|870566_871787_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP022908.1\|WP_000150017.1\|862301_863018_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP022908.1\|WP_000569884.1\|860838_861333_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP022908.1\|WP_000290485.1\|864767_865148_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP022908.1\|WP_001190695.1\|863789_864110_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP022908.1\|WP_000520233.1\|868889_869585_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP022908.1\|WP_000660172.1\|865211_865325_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001018962.1\|866946_867333_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP022908.1\|WP_000732326.1\|869602_870424_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP022908.1\|WP_000589549.1\|864253_864610_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP022908.1\|WP_001065801.1\|867325_867622_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP022908.1\|WP_000733775.1\|871875_872604_-\|staphylococcal-enterotoxin-type-K	unknown	unknown	gnl\|CDD\|280949
NZ_CP022908.1\|WP_001228759.1\|873426_873858_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000974460.1\|861731_862154_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP022908.1\|WP_001260004.1\|874344_874677_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP022908.1\|WP_000281657.1\|873874_874333_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753
NZ_CP022908.1\|WP_000932216.1\|865326_866205_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP022908.1\|WP_000422909.1\|863100_863640_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP022908.1\|WP_115276602.1\|860066_860684_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000571218.1\|867871_868897_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP022908.1\|WP_000266157.1\|870566_871787_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	6.11443e-38
NZ_CP022908.1\|WP_000150017.1\|862301_863018_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
NZ_CP022908.1\|WP_000569884.1\|860838_861333_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP022908.1\|WP_000290485.1\|864767_865148_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
NZ_CP022908.1\|WP_001190695.1\|863789_864110_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_CP022908.1\|WP_000520233.1\|868889_869585_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP022908.1\|WP_001018962.1\|866946_867333_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP022908.1\|WP_000732326.1\|869602_870424_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_CP022908.1\|WP_000589549.1\|864253_864610_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP022908.1\|WP_001065801.1\|867325_867622_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP022908.1\|WP_000733775.1\|871875_872604_-\|staphylococcal-enterotoxin-type-K	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.08384e-24
NZ_CP022908.1\|WP_000974460.1\|861731_862154_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP022908.1\|WP_001260004.1\|874344_874677_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	6.56309e-09
NZ_CP022908.1\|WP_000281657.1\|873874_874333_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	0.00011929
NZ_CP022908.1\|WP_000932216.1\|865326_866205_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
NZ_CP022908.1\|WP_000422909.1\|863100_863640_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
NZ_CP022908.1\|WP_115276602.1\|860066_860684_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.05663e-61

>NZ_CP022908.1|WP_000932216.1|865326_866205_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP022908.1|WP_000660172.1|865211_865325_+|hypothetical-protein
MKEKLLGTIIWSIATFYYSRMMEIMNLAILKIKIGGS
>NZ_CP022908.1|WP_000290485.1|864767_865148_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_CP022908.1|WP_000589549.1|864253_864610_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP022908.1|WP_001190695.1|863789_864110_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP022908.1|WP_000422909.1|863100_863640_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>NZ_CP022908.1|WP_000150017.1|862301_863018_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>NZ_CP022908.1|WP_000974460.1|861731_862154_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP022908.1|WP_000569884.1|860838_861333_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP022908.1|WP_115276602.1|860066_860684_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITARLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_CP022908.1|WP_001018962.1|866946_867333_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP022908.1|WP_001065801.1|867325_867622_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP022908.1|WP_000571218.1|867871_868897_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP022908.1|WP_000520233.1|868889_869585_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP022908.1|WP_000732326.1|869602_870424_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP022908.1|WP_000266157.1|870566_871787_-|site-specific-integrase
MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHVACDEWFQSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>NZ_CP022908.1|WP_000733775.1|871875_872604_-|staphylococcal-enterotoxin-type-K
MKKLISILLINIIILGVSNSASAQGDIGIDNLRNFYTKKDFVDLKDVKDNDTPIANQLQFSNESYDLISESKDFNKFSNFKGKKLDVFGISYNGQCNTKYIYGGVTATNEYLDKSRNIPINIWINGNHKTISTNKVSTNKKFVTAQEIDVKLRKYLQEEYNIYGHNGTKKGEEYGHKSKFYSGFNIGKVTFHLNNNDTFSYDLFYTGDDGLPKSFLKIYEDNKTVESEKFHLDVDISYKETI
>NZ_CP022908.1|WP_001228759.1|873426_873858_-|hypothetical-protein
MRKLLGLALASTLILGACGSNDGDKKEESKSYTTNDIVKGFKDNKLNVINEKEMTREDFGLAPMKTDEAKMFVVQDDKNARVMKFKNSDDLKQTKKYYDELGKESAAFYSHTHSKGKFLIQMNGDIDDATFNKYKNSMDKTLK
>NZ_CP022908.1|WP_000281657.1|873874_874333_-|ImmA/IrrE-family-metallo-endopeptidase
MYLYEKMVIENKEIPIDDGKSLGNFEGLYDNGVILINKNLSERRKAEVLYEELAHHKLTYGNILDQSKFNNRKFENYARRHGFISAVPLREIVEAYNYGVRNLYELSEYLQLSEEYILEAIEQYKKIYGIGTHYGEYSITFEPLRVFKYKEI
>NZ_CP022908.1|WP_001260004.1|874344_874677_-|helix-turn-helix-transcriptional-regulator
MRTNDEIITIIKTSMKEQNMSLSELARRVGVAKSAVSRYLNLTREFPLNRAEDFAKVLGIKTEYLLGFAEREESTKQDTIAAHLDGDFTEEELIEIRKYAELVRKAHRNQ

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Crispr_ID: NZ_CP022908_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_7

931098-931380

Orphan

Consensus_repeat	Method
AAAGNCAGCTNNNNANANNNTGCAAGTTGG	CRT

4 spacers

The CRISPR arrays of NZ_CP022908_7

>merge|NZ_CP022908|7|931098-931380|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGGCGGGGCCCCAACACAGAGGCTGGCGGAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGAGCCCCGACACAGAGAAATTAGCTCCTCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAGTGTGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAAAAAGACAGCAGTAGGATAATTTCAATTTGG

>NZ_CP022908|7|1|931098-931380|CRT
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	CGGGGCCCCAACACAGAGGCTGGCGG
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGAGCCCCGACACAGAGAAATTAGC
TCCTCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGA
AAAGTCAGCTTACAATAGTGTGCAAGTTGG	GGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCAA
AAAGACAGCAGTAGGATAATTTCAATTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000838037.1\|926968_928096_+\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_CP022908.1\|WP_001067294.1\|926230_926608_+\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023
NZ_CP022908.1\|WP_000035058.1\|925221_925815_+\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
NZ_CP022908.1\|WP_001081626.1\|921817_922246_-\|Na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
NZ_CP022908.1\|WP_000167314.1\|928403_929594_+\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_CP022908.1\|WP_000670752.1\|946352_947255_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP022908.1\|WP_000148855.1\|935545_936877_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CP022908.1\|WP_000185319.1\|931449_932379_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_CP022908.1\|WP_000054609.1\|922238_924644_-\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
NZ_CP022908.1\|WP_000758215.1\|937781_938306_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP022908.1\|WP_000781156.1\|924774_925158_-\|kinase	unknown	unknown	gnl\|CDD\|378054
NZ_CP022908.1\|WP_000066053.1\|932620_934000_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CP022908.1\|WP_011443624.1\|921476_921806_-\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
NZ_CP022908.1\|WP_000172345.1\|939056_942533_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP022908.1\|WP_000660045.1\|933989_935195_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_CP022908.1\|WP_000138487.1\|929702_930947_+\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_CP022908.1\|WP_000573077.1\|919987_921484_-\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
NZ_CP022908.1\|WP_000154930.1\|942533_946187_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP022908.1\|WP_000711486.1\|938321_938897_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP022908.1\|WP_000007967.1\|937201_937777_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000838037.1\|926968_928096_+\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_CP022908.1\|WP_001067294.1\|926230_926608_+\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
NZ_CP022908.1\|WP_000035058.1\|925221_925815_+\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
NZ_CP022908.1\|WP_001081626.1\|921817_922246_-\|Na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
NZ_CP022908.1\|WP_000167314.1\|928403_929594_+\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP022908.1\|WP_000670752.1\|946352_947255_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
NZ_CP022908.1\|WP_000148855.1\|935545_936877_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP022908.1\|WP_000185319.1\|931449_932379_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
NZ_CP022908.1\|WP_000054609.1\|922238_924644_-\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP022908.1\|WP_000758215.1\|937781_938306_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
NZ_CP022908.1\|WP_000781156.1\|924774_925158_-\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
NZ_CP022908.1\|WP_000066053.1\|932620_934000_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP022908.1\|WP_011443624.1\|921476_921806_-\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
NZ_CP022908.1\|WP_000172345.1\|939056_942533_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP022908.1\|WP_000660045.1\|933989_935195_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CP022908.1\|WP_000138487.1\|929702_930947_+\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP022908.1\|WP_000573077.1\|919987_921484_-\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP022908.1\|WP_000154930.1\|942533_946187_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP022908.1\|WP_000711486.1\|938321_938897_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
NZ_CP022908.1\|WP_000007967.1\|937201_937777_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40

>NZ_CP022908.1|WP_000138487.1|929702_930947_+|Glu/Leu/Phe/Val-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_CP022908.1|WP_000167314.1|928403_929594_+|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_CP022908.1|WP_000838037.1|926968_928096_+|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_CP022908.1|WP_001067294.1|926230_926608_+|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_CP022908.1|WP_000035058.1|925221_925815_+|peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>NZ_CP022908.1|WP_000781156.1|924774_925158_-|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>NZ_CP022908.1|WP_000054609.1|922238_924644_-|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>NZ_CP022908.1|WP_001081626.1|921817_922246_-|Na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>NZ_CP022908.1|WP_011443624.1|921476_921806_-|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>NZ_CP022908.1|WP_000573077.1|919987_921484_-|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>NZ_CP022908.1|WP_000185319.1|931449_932379_-|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_CP022908.1|WP_000066053.1|932620_934000_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_CP022908.1|WP_000660045.1|933989_935195_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>NZ_CP022908.1|WP_000148855.1|935545_936877_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_CP022908.1|WP_000007967.1|937201_937777_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>NZ_CP022908.1|WP_000758215.1|937781_938306_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>NZ_CP022908.1|WP_000711486.1|938321_938897_+|signal-peptidase-I
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>NZ_CP022908.1|WP_000172345.1|939056_942533_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKGHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_CP022908.1|WP_000154930.1|942533_946187_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP022908.1|WP_000670752.1|946352_947255_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: NZ_CP022908_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_8

1195557-1195743

Orphan

Consensus_repeat	Method
GGCGGGGCCCCAACATAGA	CRT

3 spacers

The CRISPR arrays of NZ_CP022908_8

>merge|NZ_CP022908|8|1195557-1195743|CRT
GGCGGGGCCCCAACATAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGTGGGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGTGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGA

>NZ_CP022908|8|2|1195557-1195743|CRT
GGCGGGGCCCCAACATAGA	GAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTG
GGGTGGGCCCCAACACAGA	AGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTT
GGCGGGGCCCCAACATAGT	GAAATTGGATTCCCAATTTCTACAGACAATGCAAGTT
GGCGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000231632.1\|1192731_1192965_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000584398.1\|1189336_1189843_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000739523.1\|1197601_1198327_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP022908.1\|WP_001063559.1\|1196781_1197507_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP022908.1\|WP_000765708.1\|1195073_1195220_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000600047.1\|1200958_1202449_+\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP022908.1\|WP_000149423.1\|1202756_1202984_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001032814.1\|1191924_1192110_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_025174558.1\|1191576_1191774_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001245802.1\|1204484_1204673_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_CP022908.1\|WP_000669537.1\|1190752_1191103_+\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_CP022908.1\|WP_000857483.1\|1193441_1194401_-\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388
NZ_CP022908.1\|WP_000041896.1\|1195957_1196674_-\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_CP022908.1\|WP_000791587.1\|1190101_1190599_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_CP022908.1\|WP_001074342.1\|1199788_1200721_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP022908.1\|WP_000739562.1\|1188263_1188665_-\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_CP022908.1\|WP_000398672.1\|1205584_1205719_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_CP022908.1\|WP_000793605.1\|1198764_1199766_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP022908.1\|WP_001802045.1\|1195176_1195401_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001239285.1\|1203288_1204236_-\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000739523.1\|1197601_1198327_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_CP022908.1\|WP_001239285.1\|1203288_1204236_-\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.44089e-84
NZ_CP022908.1\|WP_000600047.1\|1200958_1202449_+\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_CP022908.1\|WP_001245802.1\|1204484_1204673_+\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_CP022908.1\|WP_000669537.1\|1190752_1191103_+\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_CP022908.1\|WP_000857483.1\|1193441_1194401_-\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.27434e-141
NZ_CP022908.1\|WP_000041896.1\|1195957_1196674_-\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
NZ_CP022908.1\|WP_000791587.1\|1190101_1190599_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
NZ_CP022908.1\|WP_001074342.1\|1199788_1200721_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP022908.1\|WP_000739562.1\|1188263_1188665_-\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	1.2905e-75
NZ_CP022908.1\|WP_000398672.1\|1205584_1205719_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_CP022908.1\|WP_000793605.1\|1198764_1199766_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP022908.1\|WP_001063559.1\|1196781_1197507_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148

>NZ_CP022908.1|WP_001802045.1|1195176_1195401_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_CP022908.1|WP_000765708.1|1195073_1195220_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP022908.1|WP_000857483.1|1193441_1194401_-|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NZ_CP022908.1|WP_000231632.1|1192731_1192965_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP022908.1|WP_001032814.1|1191924_1192110_-|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP022908.1|WP_025174558.1|1191576_1191774_+|hypothetical-protein
MCKLAGPQQREIGSPIPTNNASWRGPQHRSWRKVSLQKCASWRGPNIEKLEPQFLQTMQVGVGHR
>NZ_CP022908.1|WP_000669537.1|1190752_1191103_+|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_CP022908.1|WP_000791587.1|1190101_1190599_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NZ_CP022908.1|WP_000584398.1|1189336_1189843_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_CP022908.1|WP_000739562.1|1188263_1188665_-|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDDGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
>NZ_CP022908.1|WP_000041896.1|1195957_1196674_-|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_CP022908.1|WP_001063559.1|1196781_1197507_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP022908.1|WP_000739523.1|1197601_1198327_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_CP022908.1|WP_000793605.1|1198764_1199766_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP022908.1|WP_001074342.1|1199788_1200721_+|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_CP022908.1|WP_000600047.1|1200958_1202449_+|YfcC-family-protein
MILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_CP022908.1|WP_000149423.1|1202756_1202984_+|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_CP022908.1|WP_001239285.1|1203288_1204236_-|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_CP022908.1|WP_001245802.1|1204484_1204673_+|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_CP022908.1|WP_000398672.1|1205584_1205719_+|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF

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Crispr_ID: NZ_CP022908_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_9

1900760-1900986

Orphan

Consensus_repeat	Method
GGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022908_9

>merge|NZ_CP022908|9|1900760-1900986|CRISPRCasFinder
GGGCCCCAACATAGAAGCTGGCCAATAGTTAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGG

>NZ_CP022908|9|7|1900760-1900986|CRISPRCasFinder
GGGCCCCAACATAGAAGCTGGCCAATAGTTAGCTTTCAATAATGTGCAAGTTGG	GGTAAGGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGACAATGCAAGTTGGCG
GGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_001266167.1\|1896183_1896828_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP022908.1\|WP_001091387.1\|1891939_1892797_-\|DUF1444-domain-containing-protein	unknown	unknown	gnl\|CDD\|237463
NZ_CP022908.1\|WP_001025061.1\|1915873_1917055_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP022908.1\|WP_000811163.1\|1892896_1893208_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP022908.1\|WP_000163826.1\|1894435_1894747_+\|peptidase	unknown	unknown	gnl\|CDD\|227871
NZ_CP022908.1\|WP_000836465.1\|1912835_1913147_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP022908.1\|WP_000434765.1\|1896842_1897634_-\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|223584
NZ_CP022908.1\|WP_000689580.1\|1894871_1895714_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293814
NZ_CP022908.1\|WP_000764419.1\|1918114_1918678_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377744
NZ_CP022908.1\|WP_001024576.1\|1893272_1894349_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NZ_CP022908.1\|WP_000265417.1\|1899036_1900446_-\|Mn(2+)-dependent-dipeptidase-Sapep	unknown	unknown	gnl\|CDD\|235988
NZ_CP022908.1\|WP_001217125.1\|1901804_1902500_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP022908.1\|WP_000411085.1\|1898184_1899033_-\|D-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|130191
NZ_CP022908.1\|WP_000004335.1\|1902496_1904158_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP022908.1\|WP_154801123.1\|1913168_1915583_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_CP022908.1\|WP_000285019.1\|1904564_1905833_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|367519
NZ_CP022908.1\|WP_001048368.1\|1891314_1891911_-\|DUF4479-domain-containing-protein	unknown	unknown	gnl\|CDD\|234804
NZ_CP022908.1\|WP_001051860.1\|1901365_1901788_-\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
NZ_CP022908.1\|WP_001050548.1\|1905949_1912510_-\|LPXTG-anchored-repetitive-surface-protein-SasC	unknown	unknown	gnl\|CDD\|275089
NZ_CP022908.1\|WP_000526539.1\|1917164_1918118_+\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_001266167.1\|1896183_1896828_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.40225e-87
NZ_CP022908.1\|WP_001091387.1\|1891939_1892797_-\|DUF1444-domain-containing-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
NZ_CP022908.1\|WP_001025061.1\|1915873_1917055_-\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66072e-94
NZ_CP022908.1\|WP_000811163.1\|1892896_1893208_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.34221e-24
NZ_CP022908.1\|WP_000163826.1\|1894435_1894747_+\|peptidase	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.78628e-46
NZ_CP022908.1\|WP_000836465.1\|1912835_1913147_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.46882e-25
NZ_CP022908.1\|WP_000434765.1\|1896842_1897634_-\|phosphotransferase-family-protein	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	5.2385e-83
NZ_CP022908.1\|WP_000689580.1\|1894871_1895714_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293814	cd07728, YtnP-like_MBL-fold, Bacillus subtilis YtnP and related proteins; MBL-fold metallo hydrolase domain. Bacillus subtilis YtnP inhibits the signaling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.38932e-155
NZ_CP022908.1\|WP_000764419.1\|1918114_1918678_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.38341e-67
NZ_CP022908.1\|WP_001024576.1\|1893272_1894349_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	2.36515e-152
NZ_CP022908.1\|WP_000265417.1\|1899036_1900446_-\|Mn(2+)-dependent-dipeptidase-Sapep	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NZ_CP022908.1\|WP_001217125.1\|1901804_1902500_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.1062e-94
NZ_CP022908.1\|WP_000411085.1\|1898184_1899033_-\|D-amino-acid-transaminase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	6.28892e-159
NZ_CP022908.1\|WP_000004335.1\|1902496_1904158_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.63186e-123
NZ_CP022908.1\|WP_154801123.1\|1913168_1915583_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP022908.1\|WP_000285019.1\|1904564_1905833_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0
NZ_CP022908.1\|WP_001048368.1\|1891314_1891911_-\|DUF4479-domain-containing-protein	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	7.47641e-48
NZ_CP022908.1\|WP_001051860.1\|1901365_1901788_-\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000542053
NZ_CP022908.1\|WP_001050548.1\|1905949_1912510_-\|LPXTG-anchored-repetitive-surface-protein-SasC	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	2.99104e-115
NZ_CP022908.1\|WP_000526539.1\|1917164_1918118_+\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0

>NZ_CP022908.1|WP_000265417.1|1899036_1900446_-|Mn(2+)-dependent-dipeptidase-Sapep
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>NZ_CP022908.1|WP_000411085.1|1898184_1899033_-|D-amino-acid-transaminase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>NZ_CP022908.1|WP_000434765.1|1896842_1897634_-|phosphotransferase-family-protein
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>NZ_CP022908.1|WP_001266167.1|1896183_1896828_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MRVRYKPWAKDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>NZ_CP022908.1|WP_000689580.1|1894871_1895714_-|MBL-fold-metallo-hydrolase
MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVLGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDNGENIDAYILRETLVDNN
>NZ_CP022908.1|WP_000163826.1|1894435_1894747_+|peptidase
MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>NZ_CP022908.1|WP_001024576.1|1893272_1894349_-|M42-family-metallopeptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>NZ_CP022908.1|WP_000811163.1|1892896_1893208_-|thioredoxin-family-protein
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>NZ_CP022908.1|WP_001091387.1|1891939_1892797_-|DUF1444-domain-containing-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>NZ_CP022908.1|WP_001048368.1|1891314_1891911_-|DUF4479-domain-containing-protein
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE
>NZ_CP022908.1|WP_001051860.1|1901365_1901788_-|YtxH-domain-containing-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFKEEKSKFTEYDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>NZ_CP022908.1|WP_001217125.1|1901804_1902500_-|rRNA-pseudouridine-synthase
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLTDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>NZ_CP022908.1|WP_000004335.1|1902496_1904158_-|polysaccharide-biosynthesis-protein
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNIHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>NZ_CP022908.1|WP_000285019.1|1904564_1905833_+|NAD(P)/FAD-dependent-oxidoreductase
MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHASME
>NZ_CP022908.1|WP_001050548.1|1905949_1912510_-|LPXTG-anchored-repetitive-surface-protein-SasC
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQATNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDVVSNNTALNVPTKTNENGSGGHLTLKEIQEDVRHSSNKPELVAIAEPASNRPKKRSRRAAPADPNATPADPAAAAVGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPTVNVVNNLPGFTLINGGKVGVFSHAMVRTSMFDSGDNKNYQAQGNVIALGRIHGTDTNDHGDFNGIEKALTVNPNSELIFEFNTMTTKNGQGATNVIIKNADTNDTIAEKTVEGGPTLRLFKVPDNVRNLKIQFVPKNDAITDARGIYQLKDGYKYYSFVDSIGLHSGSHVFVERRTMDPTATNNKEFTVTTSLKNNGNSGASLDTNDFVYQVQLPEGVEYVNNSLTKDFPSNNSGVDVNDMNVTYDAANRVITIKSTGGGTANSPARLMPDKILDLRYKLRVNNVPTPRTVTFNETLTYKTYTQDFINSAAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNGLKRRAQTILDENRNNVPLNKRVSQAYIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDVTEDEIQDALNQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDTRNVVNDKAREAITNINATTGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVTPDHIVRAAARDAVKQQYEAKKREIEQAEHATDEEKQVALNQLANNEKRALQNIDQAIANNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>NZ_CP022908.1|WP_000836465.1|1912835_1913147_-|rhodanese-like-domain-containing-protein
MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>NZ_CP022908.1|WP_154801123.1|1913168_1915583_-|leucine--tRNA-ligase
MNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRREINTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLAIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>NZ_CP022908.1|WP_001025061.1|1915873_1917055_-|MFS-transporter
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>NZ_CP022908.1|WP_000526539.1|1917164_1918118_+|TIGR01212-family-radical-SAM-protein
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>NZ_CP022908.1|WP_000764419.1|1918114_1918678_+|methyltransferase-domain-containing-protein
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS

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Crispr_ID: NZ_CP022908_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_10

2106229-2106307

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP022908_10

>merge|NZ_CP022908|10|2106229-2106307|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCACATTATCGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCCGCCAACCTGCA

>NZ_CP022908|10|8|2106229-2106307|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCA	CATTATCGTAAGCTGACTTTTCGTCAGCTTCTG
TGTTGGGGCCCCGCCAACCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000636142.1\|2105287_2106046_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP022908.1\|WP_000613733.1\|2111855_2112410_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP022908.1\|WP_000544969.1\|2108628_2109360_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP022908.1\|WP_000149064.1\|2103968_2104670_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP022908.1\|WP_000999713.1\|2106573_2107560_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP022908.1\|WP_000548781.1\|2113794_2114325_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP022908.1\|WP_001549145.1\|2107990_2108404_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000180461.1\|2099605_2099806_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NZ_CP022908.1\|WP_001790257.1\|2108432_2108543_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001795438.1\|2098346_2099603_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP022908.1\|WP_001250336.1\|2109361_2110675_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP022908.1\|WP_000153530.1\|2102309_2102939_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP022908.1\|WP_001790679.1\|2111548_2111641_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_001017131.1\|2102928_2103972_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP022908.1\|WP_000037075.1\|2100976_2102194_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP022908.1\|WP_000428172.1\|2100423_2100699_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000228666.1\|2099952_2100417_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP022908.1\|WP_000949467.1\|2110966_2111467_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP022908.1\|WP_001110179.1\|2104684_2105071_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000140176.1\|2112477_2113548_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000636142.1\|2105287_2106046_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NZ_CP022908.1\|WP_000613733.1\|2111855_2112410_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
NZ_CP022908.1\|WP_000544969.1\|2108628_2109360_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
NZ_CP022908.1\|WP_000149064.1\|2103968_2104670_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP022908.1\|WP_000999713.1\|2106573_2107560_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP022908.1\|WP_000548781.1\|2113794_2114325_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
NZ_CP022908.1\|WP_000180461.1\|2099605_2099806_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.44511e-24
NZ_CP022908.1\|WP_000140176.1\|2112477_2113548_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP022908.1\|WP_001795438.1\|2098346_2099603_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP022908.1\|WP_001250336.1\|2109361_2110675_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	7.18737e-99
NZ_CP022908.1\|WP_000153530.1\|2102309_2102939_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
NZ_CP022908.1\|WP_000037075.1\|2100976_2102194_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
NZ_CP022908.1\|WP_001017131.1\|2102928_2103972_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP022908.1\|WP_000228666.1\|2099952_2100417_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP022908.1\|WP_000949467.1\|2110966_2111467_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74

>NZ_CP022908.1|WP_000636142.1|2105287_2106046_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP022908.1|WP_001110179.1|2104684_2105071_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP022908.1|WP_000149064.1|2103968_2104670_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP022908.1|WP_001017131.1|2102928_2103972_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP022908.1|WP_000153530.1|2102309_2102939_-|response-regulator-transcription-factor
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP022908.1|WP_000037075.1|2100976_2102194_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP022908.1|WP_000428172.1|2100423_2100699_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP022908.1|WP_000228666.1|2099952_2100417_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP022908.1|WP_000180461.1|2099605_2099806_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>NZ_CP022908.1|WP_001795438.1|2098346_2099603_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>NZ_CP022908.1|WP_000999713.1|2106573_2107560_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP022908.1|WP_001549145.1|2107990_2108404_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>NZ_CP022908.1|WP_001790257.1|2108432_2108543_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP022908.1|WP_000544969.1|2108628_2109360_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>NZ_CP022908.1|WP_001250336.1|2109361_2110675_-|Mur-ligase-family-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP022908.1|WP_000949467.1|2110966_2111467_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP022908.1|WP_001790679.1|2111548_2111641_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP022908.1|WP_000613733.1|2111855_2112410_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP022908.1|WP_000140176.1|2112477_2113548_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP022908.1|WP_000548781.1|2113794_2114325_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: NZ_CP022908_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_11

2299712-2299792

Orphan

Consensus_repeat	Method
TTACAACTTTAGTTGTTAGGGGCT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP022908_11

>merge|NZ_CP022908|11|2299712-2299792|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCT

>NZ_CP022908|11|9|2299712-2299792|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCT	CTTATGCATGCGCTTAGCGCAGGCGCTCCTACT
TTTAAACTTTAGTTGTTAGGGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000019744.1\|2297360_2298341_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP022908.1\|WP_001292149.1\|2311285_2311720_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP022908.1\|WP_001127960.1\|2294848_2295787_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP022908.1\|WP_115276668.1\|2292542_2293916_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP022908.1\|WP_001802298.1\|2300131_2300236_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000927363.1\|2309141_2311274_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP022908.1\|WP_000003759.1\|2297038_2297359_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP022908.1\|WP_000908177.1\|2304068_2304851_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP022908.1\|WP_000648718.1\|2311719_2312826_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP022908.1\|WP_000070866.1\|2291028_2291472_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP022908.1\|WP_115276669.1\|2298606_2299698_+\|transcriptional-regulator	unknown	unknown	unknown
NZ_CP022908.1\|WP_000160304.1\|2290197_2290908_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP022908.1\|WP_001123303.1\|2291671_2292085_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP022908.1\|WP_000370924.1\|2303143_2304001_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP022908.1\|WP_000083807.1\|2307568_2309107_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP022908.1\|WP_115276670.1\|2300922_2302059_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP022908.1\|WP_001024094.1\|2296221_2296887_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP022908.1\|WP_001790138.1\|2302346_2302439_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000808817.1\|2294587_2294818_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000334465.1\|2305082_2306888_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000019744.1\|2297360_2298341_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NZ_CP022908.1\|WP_001292149.1\|2311285_2311720_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP022908.1\|WP_001127960.1\|2294848_2295787_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP022908.1\|WP_115276668.1\|2292542_2293916_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.81104e-06
NZ_CP022908.1\|WP_000083807.1\|2307568_2309107_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP022908.1\|WP_000927363.1\|2309141_2311274_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
NZ_CP022908.1\|WP_000003759.1\|2297038_2297359_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP022908.1\|WP_000908177.1\|2304068_2304851_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.86955e-104
NZ_CP022908.1\|WP_000648718.1\|2311719_2312826_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP022908.1\|WP_000070866.1\|2291028_2291472_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP022908.1\|WP_000160304.1\|2290197_2290908_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP022908.1\|WP_001123303.1\|2291671_2292085_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP022908.1\|WP_000370924.1\|2303143_2304001_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
NZ_CP022908.1\|WP_115276670.1\|2300922_2302059_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.90307e-06
NZ_CP022908.1\|WP_001024094.1\|2296221_2296887_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
NZ_CP022908.1\|WP_000334465.1\|2305082_2306888_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0

>NZ_CP022908.1|WP_115276669.1|2298606_2299698_+|transcriptional-regulator
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEYNQPK
>NZ_CP022908.1|WP_000019744.1|2297360_2298341_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP022908.1|WP_000003759.1|2297038_2297359_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP022908.1|WP_001024094.1|2296221_2296887_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NZ_CP022908.1|WP_001127960.1|2294848_2295787_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP022908.1|WP_000808817.1|2294587_2294818_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP022908.1|WP_115276668.1|2292542_2293916_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTTLFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP022908.1|WP_001123303.1|2291671_2292085_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP022908.1|WP_000070866.1|2291028_2291472_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP022908.1|WP_000160304.1|2290197_2290908_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP022908.1|WP_001802298.1|2300131_2300236_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP022908.1|WP_115276670.1|2300922_2302059_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYAVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>NZ_CP022908.1|WP_001790138.1|2302346_2302439_+|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>NZ_CP022908.1|WP_000370924.1|2303143_2304001_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>NZ_CP022908.1|WP_000908177.1|2304068_2304851_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP022908.1|WP_000334465.1|2305082_2306888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP022908.1|WP_000083807.1|2307568_2309107_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP022908.1|WP_000927363.1|2309141_2311274_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP022908.1|WP_001292149.1|2311285_2311720_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP022908.1|WP_000648718.1|2311719_2312826_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Crispr_ID: NZ_CP022908_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022908_12

2423808-2424001

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of NZ_CP022908_12

>merge|NZ_CP022908|12|2423808-2424001|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>NZ_CP022908|12|3|2423808-2424001|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022908.1\|WP_000913019.1\|2430500_2431106_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP022908.1\|WP_001161085.1\|2414744_2415062_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_115276675.1\|2420429_2421194_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP022908.1\|WP_000602937.1\|2426489_2426975_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP022908.1\|WP_000413865.1\|2418532_2419798_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP022908.1\|WP_000866971.1\|2425790_2426024_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP022908.1\|WP_000076929.1\|2429326_2430331_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP022908.1\|WP_000808500.1\|2426029_2426476_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP022908.1\|WP_000134528.1\|2428293_2428788_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP022908.1\|WP_001549681.1\|2420186_2420438_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_115276676.1\|2421788_2423000_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP022908.1\|WP_000951058.1\|2421355_2421796_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP022908.1\|WP_000643988.1\|2425184_2425784_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP022908.1\|WP_001790034.1\|2423577_2423748_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022908.1\|WP_000066900.1\|2423101_2423452_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP022908.1\|WP_000230173.1\|2424142_2425165_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP022908.1\|WP_115276678.1\|2428789_2429296_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP022908.1\|WP_000259718.1\|2426971_2428231_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP022908.1\|WP_115276674.1\|2415248_2418416_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP022908.1\|WP_000051206.1\|2414335_2414500_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022908.1\|WP_000913019.1\|2430500_2431106_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_CP022908.1\|WP_000808500.1\|2426029_2426476_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP022908.1\|WP_115276675.1\|2420429_2421194_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	4.85733e-38
NZ_CP022908.1\|WP_000602937.1\|2426489_2426975_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_CP022908.1\|WP_000413865.1\|2418532_2419798_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NZ_CP022908.1\|WP_000076929.1\|2429326_2430331_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NZ_CP022908.1\|WP_000134528.1\|2428293_2428788_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
NZ_CP022908.1\|WP_000866971.1\|2425790_2426024_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP022908.1\|WP_000951058.1\|2421355_2421796_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP022908.1\|WP_000643988.1\|2425184_2425784_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP022908.1\|WP_115276676.1\|2421788_2423000_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.68998e-72
NZ_CP022908.1\|WP_000066900.1\|2423101_2423452_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP022908.1\|WP_000230173.1\|2424142_2425165_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP022908.1\|WP_115276678.1\|2428789_2429296_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.83065e-64
NZ_CP022908.1\|WP_000259718.1\|2426971_2428231_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
NZ_CP022908.1\|WP_115276674.1\|2415248_2418416_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0

>NZ_CP022908.1|WP_001790034.1|2423577_2423748_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP022908.1|WP_000066900.1|2423101_2423452_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP022908.1|WP_115276676.1|2421788_2423000_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGINLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP022908.1|WP_000951058.1|2421355_2421796_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP022908.1|WP_115276675.1|2420429_2421194_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLHTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGTIYRFEPLV
>NZ_CP022908.1|WP_001549681.1|2420186_2420438_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP022908.1|WP_000413865.1|2418532_2419798_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP022908.1|WP_115276674.1|2415248_2418416_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDIENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVLSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP022908.1|WP_001161085.1|2414744_2415062_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP022908.1|WP_000051206.1|2414335_2414500_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP022908.1|WP_000230173.1|2424142_2425165_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP022908.1|WP_000643988.1|2425184_2425784_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP022908.1|WP_000866971.1|2425790_2426024_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP022908.1|WP_000808500.1|2426029_2426476_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP022908.1|WP_000602937.1|2426489_2426975_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP022908.1|WP_000259718.1|2426971_2428231_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP022908.1|WP_000134528.1|2428293_2428788_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_CP022908.1|WP_115276678.1|2428789_2429296_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELIK
>NZ_CP022908.1|WP_000076929.1|2429326_2430331_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP022908.1|WP_000913019.1|2430500_2431106_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	2891143-2891171	0	1.0
NZ_CP022908_6	6.1\|866333\|34\|NZ_CP022908\|CRISPRCasFinder	866333-866366	34	NZ_CP022908.1	1406528-1406561	0	1.0
NZ_CP022908_6	6.1\|866333\|34\|NZ_CP022908\|CRISPRCasFinder	866333-866366	34	NZ_CP022908.1	1494999-1495032	0	1.0
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	378740-378776	0	1.0
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	821763-821799	0	1.0
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	1051146-1051182	0	1.0
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	1406487-1406523	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	152877-152913	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	656954-656990	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	774329-774365	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	775299-775335	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	821819-821855	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	1406545-1406581	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	1494979-1495015	0	1.0
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	2107701-2107737	0	1.0
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	378857-378885	1	0.966
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	378912-378940	1	0.966
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	1900723-1900751	1	0.966
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022908.1	784727-784752	1	0.962
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022908.1	1195727-1195752	1	0.962
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022908.1	2891111-2891136	1	0.962
NZ_CP022908_7	7.1\|931128\|26\|NZ_CP022908\|CRT	931128-931153	26	NZ_CP022908.1	931072-931097	1	0.962
NZ_CP022908_7	7.3\|931242\|26\|NZ_CP022908\|CRT	931242-931267	26	NZ_CP022908.1	821791-821816	1	0.962
NZ_CP022908_8	8.1\|1195576\|37\|NZ_CP022908\|CRT	1195576-1195612	37	NZ_CP022908.1	1900720-1900756	1	0.973
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	1495037-1495073	1	0.973
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	1722295-1722331	1	0.973
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	2706745-2706781	1	0.973
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	1077280-1077316	1	0.973
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	2591872-2591908	1	0.973
NZ_CP022908_10	10.1\|2106252\|33\|NZ_CP022908\|CRISPRCasFinder	2106252-2106284	33	NZ_CP022908.1	821771-821803	1	0.97
NZ_CP022908_10	10.1\|2106252\|33\|NZ_CP022908\|CRISPRCasFinder	2106252-2106284	33	NZ_CP022908.1	1406483-1406515	1	0.97
NZ_CP022908_10	10.1\|2106252\|33\|NZ_CP022908\|CRISPRCasFinder	2106252-2106284	33	NZ_CP022908.1	1722303-1722335	1	0.97
NZ_CP022908_10	10.1\|2106252\|33\|NZ_CP022908\|CRISPRCasFinder	2106252-2106284	33	NZ_CP022908.1	2706753-2706785	1	0.97
NZ_CP022908_12	12.2\|2423887\|36\|NZ_CP022908\|CRT	2423887-2423922	36	NZ_CP022908.1	1900716-1900751	1	0.972
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	866375-866403	2	0.931
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	950767-950795	2	0.931
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	1722242-1722270	2	0.931
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	2116996-2117024	2	0.931
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	NZ_CP022908.1	2617158-2617186	2	0.931
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022908.1	784783-784808	2	0.923
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022908.1	931072-931097	2	0.923
NZ_CP022908_7	7.1\|931128\|26\|NZ_CP022908\|CRT	931128-931153	26	NZ_CP022908.1	784727-784752	2	0.923
NZ_CP022908_7	7.1\|931128\|26\|NZ_CP022908\|CRT	931128-931153	26	NZ_CP022908.1	1195727-1195752	2	0.923
NZ_CP022908_7	7.1\|931128\|26\|NZ_CP022908\|CRT	931128-931153	26	NZ_CP022908.1	2891111-2891136	2	0.923
NZ_CP022908_7	7.3\|931242\|26\|NZ_CP022908\|CRT	931242-931267	26	NZ_CP022908.1	378723-378748	2	0.923
NZ_CP022908_8	8.1\|1195576\|37\|NZ_CP022908\|CRT	1195576-1195612	37	NZ_CP022908.1	866370-866406	2	0.946
NZ_CP022908_8	8.1\|1195576\|37\|NZ_CP022908\|CRT	1195576-1195612	37	NZ_CP022908.1	1722237-1722273	2	0.946
NZ_CP022908_8	8.1\|1195576\|37\|NZ_CP022908\|CRT	1195576-1195612	37	NZ_CP022908.1	2116991-2117027	2	0.946
NZ_CP022908_8	8.1\|1195576\|37\|NZ_CP022908\|CRT	1195576-1195612	37	NZ_CP022908.1	2617155-2617191	2	0.946
NZ_CP022908_8	8.1\|1195576\|37\|NZ_CP022908\|CRT	1195576-1195612	37	NZ_CP022908.1	2891138-2891174	2	0.946
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	1191664-1191700	2	0.946
NZ_CP022908_8	8.2\|1195632\|37\|NZ_CP022908\|CRT	1195632-1195668	37	NZ_CP022908.1	1195744-1195780	2	0.946
NZ_CP022908_8	8.3\|1195688\|37\|NZ_CP022908\|CRT	1195688-1195724	37	NZ_CP022908.1	1191720-1191756	2	0.946
NZ_CP022908_10	10.1\|2106252\|33\|NZ_CP022908\|CRISPRCasFinder	2106252-2106284	33	NZ_CP022908.1	1495045-1495077	2	0.939
NZ_CP022908_12	12.1\|2423831\|33\|NZ_CP022908\|CRT	2423831-2423863	33	NZ_CP022908.1	821771-821803	2	0.939
NZ_CP022908_12	12.1\|2423831\|33\|NZ_CP022908\|CRT	2423831-2423863	33	NZ_CP022908.1	1406483-1406515	2	0.939
NZ_CP022908_12	12.1\|2423831\|33\|NZ_CP022908\|CRT	2423831-2423863	33	NZ_CP022908.1	1495045-1495077	2	0.939
NZ_CP022908_12	12.1\|2423831\|33\|NZ_CP022908\|CRT	2423831-2423863	33	NZ_CP022908.1	2706753-2706785	2	0.939
NZ_CP022908_12	12.2\|2423887\|36\|NZ_CP022908\|CRT	2423887-2423922	36	NZ_CP022908.1	1722242-1722277	2	0.944
NZ_CP022908_12	12.2\|2423887\|36\|NZ_CP022908\|CRT	2423887-2423922	36	NZ_CP022908.1	2116996-2117031	2	0.944

1. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 2891143-2891171, mismatch: 0, identity: 1.0

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtagaatttcttttcgaaa	Protospacer
*****************************

2. spacer 6.1|866333|34|NZ_CP022908|CRISPRCasFinder matches to position: 1406528-1406561, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 6.1|866333|34|NZ_CP022908|CRISPRCasFinder matches to position: 1494999-1495032, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

4. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 378740-378776, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

5. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 821763-821799, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

6. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 1051146-1051182, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

7. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 1406487-1406523, mismatch: 0, identity: 1.0

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
*************************************

8. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 152877-152913, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

9. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 656954-656990, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

10. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 774329-774365, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

11. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 775299-775335, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

12. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 821819-821855, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

13. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 1406545-1406581, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

14. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 1494979-1495015, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

15. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 2107701-2107737, mismatch: 0, identity: 1.0

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgcaagtt	Protospacer
*************************************

16. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 378857-378885, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

17. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 378912-378940, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

18. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 1900723-1900751, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

19. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to position: 784727-784752, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** ********************

20. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to position: 1195727-1195752, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
************.*************

21. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to position: 2891111-2891136, mismatch: 1, identity: 0.962

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
************.*************

22. spacer 7.1|931128|26|NZ_CP022908|CRT matches to position: 931072-931097, mismatch: 1, identity: 0.962

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaggctggtgg	Protospacer
***********************.**

23. spacer 7.3|931242|26|NZ_CP022908|CRT matches to position: 821791-821816, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacacagaagctgacga	Protospacer
**********************.***

24. spacer 8.1|1195576|37|NZ_CP022908|CRT matches to position: 1900720-1900756, mismatch: 1, identity: 0.973

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacagacaatgcaagttg	Protospacer
*******.*****************************

25. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 1495037-1495073, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agatgacgaaaagtcagcttacaataatgtgcaagtt	Protospacer
** **********************************

26. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 1722295-1722331, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttactataatgtgcaagtt	Protospacer
********************** **************

27. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 2706745-2706781, mismatch: 1, identity: 0.973

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtgcgagtt	Protospacer
********************************.****

28. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 1077280-1077316, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctacagacaatgtaagtt	Protospacer
*******************************.*****

29. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 2591872-2591908, mismatch: 1, identity: 0.973

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggattcccaatttctagagacaatgcaagtt	Protospacer
********************** **************

30. spacer 10.1|2106252|33|NZ_CP022908|CRISPRCasFinder matches to position: 821771-821803, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

31. spacer 10.1|2106252|33|NZ_CP022908|CRISPRCasFinder matches to position: 1406483-1406515, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

32. spacer 10.1|2106252|33|NZ_CP022908|CRISPRCasFinder matches to position: 1722303-1722335, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattatagtaagctgacttttcgtcagcttctg	Protospacer
****** **************************

33. spacer 10.1|2106252|33|NZ_CP022908|CRISPRCasFinder matches to position: 2706753-2706785, mismatch: 1, identity: 0.97

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
******.**************************

34. spacer 12.2|2423887|36|NZ_CP022908|CRT matches to position: 1900716-1900751, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

35. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 866375-866403, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

36. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 950767-950795, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

37. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 1722242-1722270, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

38. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 2116996-2117024, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaa	Protospacer
********.***********.********

39. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to position: 2617158-2617186, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

40. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to position: 784783-784808, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
***** ******.*************

41. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to position: 931072-931097, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccaccagcctctgtgttggggccccg	Protospacer
**.*****.*****************

42. spacer 7.1|931128|26|NZ_CP022908|CRT matches to position: 784727-784752, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*****************.** *****

43. spacer 7.1|931128|26|NZ_CP022908|CRT matches to position: 1195727-1195752, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

44. spacer 7.1|931128|26|NZ_CP022908|CRT matches to position: 2891111-2891136, mismatch: 2, identity: 0.923

cggggccccaacacagaggctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.***.********

45. spacer 7.3|931242|26|NZ_CP022908|CRT matches to position: 378723-378748, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcga	CRISPR spacer
cggggccccaacaaagaagctgacga	Protospacer
************* ********.***

46. spacer 8.1|1195576|37|NZ_CP022908|CRT matches to position: 866370-866406, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

47. spacer 8.1|1195576|37|NZ_CP022908|CRT matches to position: 1722237-1722273, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

48. spacer 8.1|1195576|37|NZ_CP022908|CRT matches to position: 2116991-2117027, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaggaaattctacagacaatgcaagttg	Protospacer
*******.***.*************************

49. spacer 8.1|1195576|37|NZ_CP022908|CRT matches to position: 2617155-2617191, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaggcaatgcaagttg	Protospacer
*******.****************.************

50. spacer 8.1|1195576|37|NZ_CP022908|CRT matches to position: 2891138-2891174, mismatch: 2, identity: 0.946

gaatttcaaaaagaaattctacagacaatgcaagttg	CRISPR spacer
gaatttcgaaaagaaattctacaaacaatgcaagttg	Protospacer
*******.***************.*************

51. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 1191664-1191700, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcgaaaagtcagcttacaaaaatgtgcaagtt	Protospacer
*****.****************** ************

52. spacer 8.2|1195632|37|NZ_CP022908|CRT matches to position: 1195744-1195780, mismatch: 2, identity: 0.946

agctgacgaaaagtcagcttacaataatgtgcaagtt	CRISPR spacer
agctggcggaaagtcagcttacaataatgtgcaagtt	Protospacer
*****.**.****************************

53. spacer 8.3|1195688|37|NZ_CP022908|CRT matches to position: 1191720-1191756, mismatch: 2, identity: 0.946

gaaattggattcccaatttctacagacaatgcaagtt	CRISPR spacer
gaaattggaaccccaatttctacagacaatgcaagtt	Protospacer
********* .**************************

54. spacer 10.1|2106252|33|NZ_CP022908|CRISPRCasFinder matches to position: 1495045-1495077, mismatch: 2, identity: 0.939

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
******.******************* ******

55. spacer 12.1|2423831|33|NZ_CP022908|CRT matches to position: 821771-821803, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

56. spacer 12.1|2423831|33|NZ_CP022908|CRT matches to position: 1406483-1406515, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

57. spacer 12.1|2423831|33|NZ_CP022908|CRT matches to position: 1495045-1495077, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

58. spacer 12.1|2423831|33|NZ_CP022908|CRT matches to position: 2706753-2706785, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

59. spacer 12.2|2423887|36|NZ_CP022908|CRT matches to position: 1722242-1722277, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

60. spacer 12.2|2423887|36|NZ_CP022908|CRT matches to position: 2116996-2117031, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022908_1	1.1\|46254\|53\|NZ_CP022908\|CRISPRCasFinder	46254-46306	53	NZ_LR735436	Staphylococcus epidermidis strain none isolate Se_BPH0736 plasmid 3	9028-9080	1	0.981
NZ_CP022908_7	7.4\|931298\|53\|NZ_CP022908\|CRT	931298-931350	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
NZ_CP022908_5	5.1\|821735\|26\|NZ_CP022908\|CRISPRCasFinder	821735-821760	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808
NZ_CP022908_7	7.3\|931242\|26\|NZ_CP022908\|CRT	931242-931267	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_CP022908_4	4.1\|816333\|29\|NZ_CP022908\|CRISPRCasFinder	816333-816361	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
NZ_CP022908_10	10.1\|2106252\|33\|NZ_CP022908\|CRISPRCasFinder	2106252-2106284	33	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159745-159777	10	0.697

1. spacer 1.1|46254|53|NZ_CP022908|CRISPRCasFinder matches to NZ_LR735436 (Staphylococcus epidermidis strain none isolate Se_BPH0736 plasmid 3) position: , mismatch: 1, identity: 0.981

ctataataactaacgaaagaattataacacctattatatagagaataaagttt	CRISPR spacer
ctataataactaacgaaagaattataacacctattatatagagaataaagatt	Protospacer
************************************************** **

2. spacer 7.4|931298|53|NZ_CP022908|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ggtgggacgacgaaataaattttgcgaaaatatcatttctgtcccactcccaa	CRISPR spacer
ggtgggacgacgaaataaattttgagaaactatcatttctgtcccactccctt	Protospacer
************************ **** *********************

3. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

4. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtctgggcctac	Protospacer
****************. *****.

5. spacer 5.1|821735|26|NZ_CP022908|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtttggccctga	Protospacer
***************** ** **. .

6. spacer 7.3|931242|26|NZ_CP022908|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcga	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

7. spacer 4.1|816333|29|NZ_CP022908|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtaggatttcttctaagtg	Protospacer
**************.*******.* .. .

8. spacer 10.1|2106252|33|NZ_CP022908|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 10, identity: 0.697

cattatcgtaagctgacttttcgtcagcttctg	CRISPR spacer
ttttatcgtaaggtgagttttcgtcaagcacct	Protospacer
. ********** *** *********. . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

12269 : 71484

Staphylococcus_phage(35.29%)

transposase,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000884334.1\|12269_13556_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.7e-88	51.2
WP_000207095.1\|14202_14898_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_000628050.1\|14894_15224_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_000186481.1\|15586_16555_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_001791710.1\|16845_17784_+	YybS family protein	NA	NA	NA	NA
WP_001081634.1\|17798_19766_+	cyclic-di-AMP phosphodiesterase GdpP	NA	NA	NA	NA
WP_000864305.1\|19762_20209_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_000375647.1\|20240_21641_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	5.4e-111	48.1
WP_000095327.1\|21918_23202_+	adenylosuccinate synthase	L7Y4J5	Megavirus	2.3e-68	34.6
WP_000101976.1\|24405_25107_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-42	39.2
WP_000871607.1\|25119_26946_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.6e-30	31.3
WP_001060131.1\|26938_28273_+	hypothetical protein	NA	NA	NA	NA
WP_001104172.1\|28273_29062_+	hypothetical protein	NA	NA	NA	NA
WP_000088648.1\|29451_30252_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	4.6e-38	35.9
WP_000645780.1\|30479_32798_+	LPXTG-anchored adenosine synthase AdsA	NA	NA	NA	NA
WP_000704775.1\|33165_33645_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_000566670.1\|33864_35121_+	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_001282728.1\|35535_35775_+	hypothetical protein	NA	NA	NA	NA
WP_001106057.1\|35806_36481_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	2.6e-127	99.1
WP_020444595.1\|36516_36906_+	hydroxymethylglutaryl-CoA synthase family protein	NA	NA	NA	NA
WP_000958858.1\|37742_38486_+	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_000872606.1\|38582_39011_+	MaoC family dehydratase	NA	NA	NA	NA
WP_063852655.1\|39056_41066_-	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	NA	NA	NA	NA
WP_001549960.1\|41162_42149_+	beta-lactam sensor/signal transducer MecR1	NA	NA	NA	NA
WP_115276553.1\|42120_42378_+	DUF3387 domain-containing protein	NA	NA	NA	NA
WP_162797737.1\|44030_44537_-	DUF1643 domain-containing protein	NA	NA	NA	NA
WP_115276555.1\|44551_44710_-	hypothetical protein	NA	NA	NA	NA
WP_001106022.1\|44756_45431_-\|transposase	IS6-like element IS257 family transposase	A0A0N9SKD3	Staphylococcus_phage	6.2e-129	100.0
WP_115276556.1\|45460_46204_-	RepB family plasmid replication initiator protein	NA	NA	NA	NA
WP_080351733.1\|46915_47362_-	DUF334 domain-containing protein	NA	NA	NA	NA
WP_049325240.1\|47423_48434_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_002485398.1\|48420_48618_-	hypothetical protein	NA	NA	NA	NA
WP_115276557.1\|48593_48983_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_002485551.1\|49251_49530_-	hypothetical protein	NA	NA	NA	NA
WP_115276558.1\|49626_50427_-	ABC transporter permease	NA	NA	NA	NA
WP_053522978.1\|50522_50729_-	hypothetical protein	NA	NA	NA	NA
WP_001106022.1\|52470_53145_+\|transposase	IS6-like element IS257 family transposase	A0A0N9SKD3	Staphylococcus_phage	6.2e-129	100.0
WP_001096887.1\|53824_54619_-	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_115276559.1\|54711_55254_-	streptothricin N-acetyltransferase Sat4	A0A1B0RXL7	Streptococcus_phage	2.0e-93	99.4
WP_001255866.1\|55250_56159_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
WP_000662263.1\|56191_56926_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_001105999.1\|57636_58311_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	2.0e-127	99.1
WP_000122374.1\|59878_61120_-	plasmid recombination protein	NA	NA	NA	NA
WP_089535971.1\|61305_62685_-	tetracycline efflux MFS transporter Tet(K)	NA	NA	NA	NA
WP_001105999.1\|62884_63559_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	2.0e-127	99.1
WP_162564149.1\|63841_65188_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000525462.1\|65487_65895_+	Hg(II)-responsive transcriptional regulator MerR	NA	NA	NA	NA
WP_115276560.1\|65911_66397_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_000010352.1\|66393_67074_+	cytochrome c biosynthesis protein	NA	NA	NA	NA
WP_001794630.1\|67161_67548_+	mercuric transport protein MerT	NA	NA	NA	NA
WP_000193219.1\|67605_69249_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.7e-50	29.4
WP_000790333.1\|69330_69981_+	organomercurial lyase MerB	NA	NA	NA	NA
WP_000377078.1\|70175_70691_-	hypothetical protein	NA	NA	NA	NA
WP_052998601.1\|70809_71484_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	7.6e-127	98.7

DBSCAN-SWA_2

753418 : 761238

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244412.1\|753418_754474_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
WP_000149344.1\|754473_755160_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|755134_755608_-	DoxX family protein	NA	NA	NA	NA
WP_001093553.1\|755949_756390_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637687.1\|756669_757254_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|757352_758066_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|758069_758489_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|758490_759159_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1\|759509_760103_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217785.1\|760086_761238_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_3

773210 : 787941

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|773210_774269_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197271.1\|774619_775162_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429014.1\|775785_776703_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_001790641.1\|776793_776895_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|776972_778478_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|778818_779319_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|779338_780205_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|781005_781404_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|781366_783472_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|783589_784561_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|785074_785230_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|785268_786240_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|786226_787183_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|787179_787941_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_4

867871 : 889080

Staphylococcus_phage(76.92%)

terminase,integrase,coat

attL 870408:870424|attR 886343:886359

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571218.1\|867871_868897_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-27	36.8
WP_000520233.1\|868889_869585_+	ABC transporter permease	NA	NA	NA	NA
WP_000732326.1\|869602_870424_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
870408:870424	attL	NA	NA	NA	NA
WP_000266157.1\|870566_871787_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	6.4e-100	47.5
WP_000733775.1\|871875_872604_-	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	1.9e-22	32.3
WP_001228759.1\|873426_873858_-	hypothetical protein	Q4ZCB6	Staphylococcus_virus	5.1e-36	56.0
WP_000281657.1\|873874_874333_-	ImmA/IrrE family metallo-endopeptidase	A0A0H4J322	Staphylococcus_phage	5.1e-66	83.0
WP_001260004.1\|874344_874677_-	helix-turn-helix transcriptional regulator	A0A1J0MFC1	Staphylococcus_phage	1.6e-37	74.5
WP_112368207.1\|874869_875109_+	helix-turn-helix transcriptional regulator	A0A2H4J9X2	uncultured_Caudovirales_phage	1.7e-33	88.6
WP_000091731.1\|875124_875397_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	9.7e-41	90.0
WP_000784875.1\|875408_875555_+	hypothetical protein	NA	NA	NA	NA
WP_001058486.1\|875547_875757_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	1.7e-29	94.2
WP_001103942.1\|875759_876080_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.3e-20	51.9
WP_001002732.1\|876143_877013_+	hypothetical protein	A0A1W6JQL5	Staphylococcus_phage	3.4e-156	92.7
WP_000390455.1\|877029_878487_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	1.0e-277	96.1
WP_001039168.1\|878787_879150_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
WP_000998181.1\|879151_879436_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.9e-47	95.7
WP_001019764.1\|879432_880074_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	1.5e-108	91.5
WP_001190615.1\|880590_880932_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
WP_000846285.1\|880943_881522_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
WP_000448101.1\|881539_881758_+	hypothetical protein	NA	NA	NA	NA
WP_000771368.1\|881808_882336_+\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
WP_000358777.1\|882338_882680_+	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.4e-57	98.2
WP_001293067.1\|882676_883246_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.0e-100	97.9
WP_000278085.1\|883553_884354_+	staphylococcal enterotoxin type B	A0A097PAT7	Streptococcus_pyogenes_phage	1.0e-53	49.4
WP_001035631.1\|884431_884989_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	1.4e-70	73.8
WP_001795626.1\|885361_885514_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	7.6e-19	98.0
WP_000139424.1\|885584_885695_+	hypothetical protein	W5R8J7	Staphylococcus_phage	2.4e-11	94.4
WP_000382163.1\|885681_885882_+	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0
WP_000752917.1\|886712_886907_+	CsbD family protein	NA	NA	NA	NA
886343:886359	attR	NA	NA	NA	NA
WP_001183858.1\|887139_887991_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_000168845.1\|888318_889080_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3

DBSCAN-SWA_5

958044 : 1020337

Staphylococcus_phage(18.18%)

protease,transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195429.1\|958044_959217_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_115276605.1\|959429_960071_+	L-threonylcarbamoyladenylate synthase	NA	NA	NA	NA
WP_001037436.1\|960063_961182_+	membrane protein	NA	NA	NA	NA
WP_000695342.1\|961165_961681_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_115276606.1\|961990_962425_+	MAP domain-containing protein	NA	NA	NA	NA
WP_000682089.1\|962681_962867_-	YjzD family protein	NA	NA	NA	NA
WP_001100525.1\|963161_964103_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_000081240.1\|964114_965359_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_000915155.1\|965413_965785_-	DUF3899 domain-containing protein	NA	NA	NA	NA
WP_000521533.1\|966027_966954_+	ABC transporter permease	NA	NA	NA	NA
WP_000829632.1\|966953_968024_+	ABC transporter permease	NA	NA	NA	NA
WP_000140050.1\|968040_969123_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.4e-19	28.8
WP_000786737.1\|969112_970054_+	ATP-binding cassette domain-containing protein	F2Y1V6	Organic_Lake_phycodnavirus	2.7e-05	26.9
WP_000197019.1\|970072_971728_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000517187.1\|971939_973655_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001067038.1\|973705_974692_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.0e-15	30.4
WP_000427770.1\|974694_975675_+	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-16	34.1
WP_000593417.1\|975667_976630_+	ABC transporter permease	NA	NA	NA	NA
WP_001180262.1\|976641_977523_+	ABC transporter permease	NA	NA	NA	NA
WP_000448934.1\|977564_978554_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|978848_979244_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217730.1\|979614_980334_+	adaptor protein MecA	NA	NA	NA	NA
WP_000959287.1\|980454_981441_+	competence protein CoiA	NA	NA	NA	NA
WP_000082731.1\|981488_983297_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	9.3e-47	24.4
WP_000896697.1\|983756_984563_-	DsbA family protein	NA	NA	NA	NA
WP_000214065.1\|984585_984951_-	hypothetical protein	NA	NA	NA	NA
WP_000224622.1\|985054_985648_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242102.1\|985833_986181_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|986197_986833_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|986849_987659_+	NAD kinase	NA	NA	NA	NA
WP_000669939.1\|987655_988510_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000062417.1\|988530_989916_+	magnesium transporter	NA	NA	NA	NA
WP_000395153.1\|989925_991770_+	sodium:proton antiporter	NA	NA	NA	NA
WP_000933195.1\|992047_992818_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|993012_994098_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570699.1\|994439_996008_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_001288681.1\|996149_996908_+	esterase family protein	NA	NA	NA	NA
WP_115276607.1\|997101_997611_+	hypothetical protein	NA	NA	NA	NA
WP_001795545.1\|997723_998932_-	MFS transporter	NA	NA	NA	NA
WP_000258650.1\|998891_1000067_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340118.1\|1000499_1001981_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001795833.1\|1001964_1002225_+	hypothetical protein	NA	NA	NA	NA
WP_001049959.1\|1002224_1003787_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	4.9e-36	28.2
WP_000928413.1\|1004088_1004892_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_115276608.1\|1005110_1007435_+\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
WP_115276609.1\|1007451_1008810_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414177.1\|1008948_1010460_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|1010946_1011516_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|1011725_1011944_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000668820.1\|1012024_1013011_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1013209_1013386_+	YkvS family protein	NA	NA	NA	NA
WP_001033867.1\|1013400_1014003_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001790623.1\|1014919_1015021_+	hypothetical protein	NA	NA	NA	NA
WP_001790097.1\|1015030_1015303_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000870806.1\|1015346_1017311_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000668623.1\|1017313_1017634_+	YxeA family protein	NA	NA	NA	NA
WP_000571178.1\|1017630_1018272_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-19	33.7
WP_001795544.1\|1018359_1018650_-	hypothetical protein	NA	NA	NA	NA
WP_000410721.1\|1018928_1019138_+	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|1019164_1020337_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0

DBSCAN-SWA_6

1052659 : 1061132

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1052659_1053142_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010412.1\|1053128_1054253_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1054256_1054961_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1054960_1055224_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1055225_1055897_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1055889_1058079_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1058057_1059542_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030812.1\|1059534_1060563_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238664.1\|1060565_1061132_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_7

1112725 : 1172373

Staphylococcus_phage(80.88%)

capsid,portal,head,tRNA,plate,terminase,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000401377.1\|1112725_1113208_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
WP_000843611.1\|1113269_1114409_-	nucleotidyltransferase	NA	NA	NA	NA
WP_000872158.1\|1114535_1115093_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000290472.1\|1115172_1115346_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_112367585.1\|1115462_1116848_-	recombinase family protein	I1W625	Staphylococcus_phage	5.5e-265	99.8
WP_000525009.1\|1117415_1117877_-	hypothetical protein	W5R9J0	Staphylococcus_phage	1.2e-83	100.0
WP_001260487.1\|1117889_1118213_-	helix-turn-helix transcriptional regulator	A0A0H3U2V8	Staphylococcus_phage	2.0e-53	100.0
WP_000272859.1\|1118376_1118625_+	helix-turn-helix transcriptional regulator	A0A2K9VBT6	Staphylococcus_phage	1.7e-39	100.0
WP_023487065.1\|1118637_1119081_+	hypothetical protein	W5R971	Staphylococcus_phage	4.4e-75	99.3
WP_033861758.1\|1119095_1119275_+	hypothetical protein	A0A0H3U490	Staphylococcus_phage	2.2e-25	98.3
WP_000394410.1\|1119375_1119858_-	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
WP_000933365.1\|1120303_1120489_+	helix-turn-helix transcriptional regulator	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
WP_001148586.1\|1120490_1121240_+	antirepressor	A0A0N7E0R7	Staphylococcus_phage	1.2e-136	100.0
WP_000395457.1\|1121406_1121637_-	hypothetical protein	R4IG40	Staphylococcus_phage	2.3e-35	100.0
WP_031929005.1\|1121816_1121978_+	DUF1270 family protein	Q4ZAZ7	Staphylococcus_virus	1.2e-19	98.1
WP_115284601.1\|1122072_1122333_+	DUF1108 family protein	Q4ZDR5	Staphylococcus_virus	1.7e-42	97.7
WP_000815403.1\|1122342_1122564_+	DUF2483 domain-containing protein	A0A1X9H047	Staphylococcus_phage	1.2e-33	100.0
WP_000139720.1\|1122556_1123180_+	DUF1071 domain-containing protein	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
WP_000934384.1\|1123179_1123605_+	single-stranded DNA-binding protein	B7T0A5	Staphylococcus_virus	1.6e-58	88.7
WP_001004506.1\|1123615_1124167_+	HNH endonuclease	A0A2H4PQR4	Staphylococcus_phage	1.6e-106	100.0
WP_115284602.1\|1124167_1124836_+	hypothetical protein	A0A0E3XBQ6	Staphylococcus_phage	5.7e-127	99.1
WP_031929003.1\|1124835_1125600_+	AP2 domain-containing protein	A0A2I6PDA5	Staphylococcus_phage	1.2e-144	100.0
WP_115284603.1\|1125592_1126360_+	alpha/beta hydrolase	A0A2I6PDA9	Staphylococcus_phage	7.1e-113	96.1
WP_031790239.1\|1126369_1127143_+	ATP-binding protein	A0A2I6PDA0	Staphylococcus_phage	2.7e-144	99.6
WP_000256596.1\|1127136_1127295_+	hypothetical protein	A0A2I6PDX0	Staphylococcus_phage	5.8e-22	96.2
WP_001556702.1\|1127307_1127529_+	DUF3269 family protein	A0A1W6JQ35	Staphylococcus_phage	4.9e-35	98.6
WP_015997090.1\|1127538_1127943_+	DUF1064 domain-containing protein	C5I647	Staphylococcus_phage	1.6e-68	100.0
WP_001187254.1\|1127947_1128133_+	DUF3113 family protein	Q4ZA46	Staphylococcus_virus	4.1e-27	100.0
WP_115284604.1\|1128133_1128748_+	hypothetical protein	Q4ZAC3	Staphylococcus_virus	1.4e-66	88.2
WP_000228426.1\|1128751_1128994_+	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	1.2e-39	97.5
WP_000695762.1\|1129006_1129408_+	hypothetical protein	Q4ZAC1	Staphylococcus_virus	1.1e-69	100.0
WP_000979209.1\|1129404_1129752_+	hypothetical protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
WP_115284605.1\|1129748_1130057_+	hypothetical protein	C8CH03	Staphylococcus_phage	3.1e-51	97.1
WP_001065023.1\|1130049_1130286_+	DUF1024 family protein	C8CH04	Staphylococcus_phage	1.1e-35	100.0
WP_000185680.1\|1130290_1130827_+	hypothetical protein	A0A1P8L6E0	Staphylococcus_phage	2.1e-95	100.0
WP_064221812.1\|1130863_1131100_+	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	4.5e-34	97.4
WP_115284606.1\|1131124_1131361_+	hypothetical protein	S4SWB7	Staphylococcus_phage	2.2e-33	91.0
WP_000591891.1\|1131353_1131527_+	transcriptional activator RinB	R4IFL3	Staphylococcus_phage	1.1e-21	98.2
WP_000989954.1\|1131527_1131893_+	hypothetical protein	Q4ZBJ9	Staphylococcus_phage	3.6e-59	100.0
WP_000989960.1\|1131893_1132040_+	hypothetical protein	Q4ZBJ8	Staphylococcus_phage	7.5e-16	100.0
WP_000162702.1\|1132063_1132486_+	RinA family phage transcriptional activator	Q4ZBJ7	Staphylococcus_phage	1.2e-74	100.0
WP_050960855.1\|1132813_1133308_+\|terminase	terminase	A0A0E3T9M2	Staphylococcus_phage	1.4e-82	98.8
WP_031907817.1\|1133300_1134509_+\|terminase	PBSX family phage terminase large subunit	A0A0E3TAL1	Staphylococcus_phage	4.7e-236	100.0
WP_001159668.1\|1134462_1135941_+\|portal	phage portal protein	Q4ZB45	Staphylococcus_virus	3.3e-284	99.6
WP_001795666.1\|1135879_1136860_+\|capsid	minor capsid protein	Q4ZAW9	Staphylococcus_virus	3.3e-179	98.2
WP_000366932.1\|1136957_1137554_+	hypothetical protein	R4IG73	Staphylococcus_phage	5.6e-73	100.0
WP_001135558.1\|1137574_1138399_+\|capsid	N4-gp56 family major capsid protein	R4IH32	Staphylococcus_phage	5.6e-148	100.0
WP_115284607.1\|1138415_1138742_+	Rho termination protein	A0A0E3TAL3	Staphylococcus_phage	7.3e-51	99.1
WP_000338935.1\|1138741_1139056_+\|head,tail	phage head-tail adapter protein	R4IFL8	Staphylococcus_phage	4.0e-54	100.0
WP_031927508.1\|1139048_1139384_+\|head	phage head closure protein	A0A0H4ISR6	Staphylococcus_phage	8.8e-60	98.2
WP_001151335.1\|1139370_1139784_+	HK97 gp10 family phage protein	R4IG77	Staphylococcus_phage	2.0e-77	100.0
WP_000270196.1\|1139796_1140234_+	DUF3168 domain-containing protein	A0A0E3T9M9	Staphylococcus_phage	2.1e-77	100.0
WP_000046067.1\|1140220_1140781_+	hypothetical protein	A0A0H4ITY2	Staphylococcus_phage	5.9e-101	100.0
WP_000141082.1\|1140842_1141337_+	hypothetical protein	R4IFM1	Staphylococcus_phage	4.3e-87	100.0
WP_001580347.1\|1141357_1141699_+	hypothetical protein	A0A2H4PQL5	Staphylococcus_phage	3.5e-56	100.0
WP_115284608.1\|1141701_1144671_+\|terminase	terminase	Q4ZAG7	Staphylococcus_virus	1.9e-262	99.1
WP_115284609.1\|1144685_1145621_+\|tail	phage tail protein	R4IH41	Staphylococcus_phage	1.2e-178	99.0
WP_001144709.1\|1145631_1147518_+	peptidase	R4IGA4	Staphylococcus_phage	0.0e+00	99.8
WP_103205208.1\|1147530_1149429_+	hypothetical protein	Q4ZBQ2	Staphylococcus_phage	0.0e+00	99.4
WP_115284610.1\|1149428_1151252_+\|plate	BppU family phage baseplate upper protein	Q4ZBH7	Staphylococcus_virus	0.0e+00	98.8
WP_000705909.1\|1151251_1151629_+	DUF2977 domain-containing protein	A9CRC6	Staphylococcus_phage	5.6e-55	100.0
WP_001790193.1\|1151632_1151806_+	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_000466769.1\|1151846_1152146_+	DUF2951 domain-containing protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
WP_115284611.1\|1152282_1154157_+	CHAP domain-containing protein	Q4ZBP7	Staphylococcus_phage	0.0e+00	99.5
WP_115284612.1\|1154169_1155408_+\|plate	BppU family phage baseplate upper protein	Q4ZB96	Staphylococcus_virus	1.0e-206	98.3
WP_000387943.1\|1155412_1155808_+	hypothetical protein	A0A0H4IPB8	Staphylococcus_phage	8.8e-67	97.7
WP_000354128.1\|1155862_1156300_+\|holin	phage holin	S4SVG2	Staphylococcus_phage	4.1e-73	99.3
WP_115284613.1\|1156280_1157726_+	CHAP domain-containing protein	B2ZZ06	Staphylococcus_phage	5.9e-294	99.2
WP_000344116.1\|1158391_1158703_+	DUF3467 domain-containing protein	A0A2H4PQQ9	Staphylococcus_phage	4.1e-51	100.0
WP_001251276.1\|1158689_1159073_+	hypothetical protein	A0A2H4PQP6	Staphylococcus_phage	6.1e-65	99.2
WP_115276613.1\|1159256_1161194_-	heme uptake protein IsdB	NA	NA	NA	NA
WP_000160859.1\|1161396_1162449_-	LPXTG-anchored heme-scavenging protein IsdA	NA	NA	NA	NA
WP_115276614.1\|1162657_1163341_+	heme uptake protein IsdC	NA	NA	NA	NA
WP_001246698.1\|1163340_1164417_+	hypothetical protein	NA	NA	NA	NA
WP_001220199.1\|1164413_1165292_+	heme ABC transporter substrate-binding protein IsdE	NA	NA	NA	NA
WP_001548422.1\|1165301_1166270_+	iron ABC transporter permease	NA	NA	NA	NA
WP_001242429.1\|1166331_1167066_+	class B sortase	NA	NA	NA	NA
WP_000670950.1\|1167084_1167408_+	staphylobilin-forming heme oxygenase IsdG	NA	NA	NA	NA
WP_001788617.1\|1167444_1167552_+	hypothetical protein	NA	NA	NA	NA
WP_000435374.1\|1167791_1168532_+	RNA methyltransferase	NA	NA	NA	NA
WP_000003559.1\|1168912_1169971_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
WP_000908982.1\|1169970_1172373_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA

DBSCAN-SWA_8

1361772 : 1369126

Staphylococcus_phage(85.71%)

capsid,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001789891.1\|1361772_1361970_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
WP_001789892.1\|1362658_1362883_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-18	71.0
WP_001002340.1\|1363176_1363383_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
WP_000195429.1\|1363818_1364991_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_115284614.1\|1365415_1365514_+	hypothetical protein	NA	NA	NA	NA
WP_000006110.1\|1365933_1366119_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_000477492.1\|1366630_1366735_+	hypothetical protein	NA	NA	NA	NA
WP_001791646.1\|1366689_1366863_+	hypothetical protein	NA	NA	NA	NA
WP_000956747.1\|1366863_1367115_+	hypothetical protein	NA	NA	NA	NA
WP_000899337.1\|1367160_1367745_+\|capsid	minor capsid protein	Q4ZE35	Staphylococcus_virus	2.0e-30	72.0
WP_000195429.1\|1367953_1369126_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0

DBSCAN-SWA_9

1549001 : 1637408

106

Staphylococcus_phage(80.26%)

capsid,head,portal,integrase,tRNA,plate,terminase,protease,tail,holin

attL 1590063:1590080|attR 1635925:1635942

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858789.1\|1549001_1550294_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
WP_000525078.1\|1550615_1553309_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000049919.1\|1553332_1554304_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361544.1\|1554290_1555493_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	3.2e-35	42.5
WP_000690027.1\|1555497_1556640_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1556880_1557198_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1557534_1558215_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000152734.1\|1558286_1558874_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000004947.1\|1558863_1559439_-	IDEAL domain-containing protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
WP_011443634.1\|1559452_1560556_-	hypothetical protein	NA	NA	NA	NA
WP_000245895.1\|1560703_1562002_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776323.1\|1562011_1563076_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269929.1\|1563101_1564268_-	chorismate synthase	A0A291AU41	Pandoravirus	7.6e-34	32.1
WP_000789522.1\|1564653_1564854_-	hypothetical protein	NA	NA	NA	NA
WP_000442480.1\|1565062_1565512_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_001817755.1\|1565603_1566548_-	heptaprenyl diphosphate synthase subunit II	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774684.1\|1566564_1567290_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450553.1\|1567292_1567865_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1568295_1568568_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161738.1\|1568738_1569737_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1569753_1571064_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_115276631.1\|1571285_1572461_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_001789944.1\|1572717_1572909_-	hypothetical protein	NA	NA	NA	NA
WP_001789945.1\|1573025_1573142_-	hypothetical protein	NA	NA	NA	NA
WP_000644391.1\|1573172_1573832_-	(d)CMP kinase	NA	NA	NA	NA
WP_115276632.1\|1573908_1574877_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1574991_1575978_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_001789943.1\|1576138_1576255_-	hypothetical protein	NA	NA	NA	NA
WP_000069282.1\|1576379_1577840_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902119.1\|1577992_1579372_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
WP_001163801.1\|1579361_1580315_-	hypothetical protein	NA	NA	NA	NA
WP_001151997.1\|1580422_1580671_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186912.1\|1580776_1581322_-	ECF transporter S component	NA	NA	NA	NA
WP_001789947.1\|1581600_1581720_-	hypothetical protein	NA	NA	NA	NA
WP_000913219.1\|1581918_1582833_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001033757.1\|1582847_1583054_-	hypothetical protein	NA	NA	NA	NA
WP_000472936.1\|1583046_1583985_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476873.1\|1584042_1584960_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000464818.1\|1585050_1585398_-	hypothetical protein	Q4ZCJ7	Staphylococcus_virus	3.0e-26	100.0
WP_000180531.1\|1585448_1586132_-	hypothetical protein	A0A0A7S0U2	Clostridium_phage	1.1e-13	28.3
WP_000990948.1\|1586128_1586311_-	hypothetical protein	NA	NA	NA	NA
WP_031924639.1\|1588076_1589531_-	CHAP domain-containing protein	I1W626	Staphylococcus_phage	4.1e-287	99.0
WP_000339141.1\|1589541_1589844_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000466784.1\|1589979_1590279_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
1590063:1590080	attL	NA	NA	NA	NA
WP_000916020.1\|1590324_1590489_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1590481_1590871_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_115276633.1\|1590870_1592337_-\|plate	BppU family phage baseplate upper protein	A0A2I6PDE3	Staphylococcus_phage	2.0e-257	94.3
WP_000429558.1\|1592336_1594247_-	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_000179858.1\|1594262_1594553_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000384474.1\|1594552_1596136_-	peptidase	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_001190533.1\|1596144_1596969_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_031860857.1\|1596968_1603169_-\|tail	phage tail tape measure protein	U5U762	Staphylococcus_phage	0.0e+00	99.8
WP_000438833.1\|1603182_1603341_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589167.1\|1603382_1603733_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000169127.1\|1603790_1604246_-	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
WP_000807536.1\|1604337_1604979_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_001023802.1\|1605013_1605409_-	DUF3168 domain-containing protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
WP_000110020.1\|1605409_1605811_-	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
WP_000395501.1\|1605807_1606140_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
WP_000050973.1\|1606151_1606430_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142739.1\|1606498_1607662_-\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
WP_115276634.1\|1607673_1608447_-\|protease	Clp protease ClpP	M1TAZ4	Staphylococcus_phage	2.7e-136	99.6
WP_001100669.1\|1608430_1609669_-\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
WP_115276635.1\|1609673_1611365_-\|terminase	terminase large subunit	A0A2I6PE44	Staphylococcus_phage	0.0e+00	99.6
WP_000778932.1\|1611354_1611660_-\|terminase	terminase	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
WP_015978060.1\|1611788_1612103_-	HNH endonuclease	Q4ZCU3	Staphylococcus_virus	2.5e-56	100.0
WP_031883903.1\|1612259_1612697_-	transcriptional regulator	A0A2I6PEB8	Staphylococcus_phage	1.0e-76	100.0
WP_115276636.1\|1612709_1614077_-	DEAD/DEAH box helicase	A0A0K1LKG3	Staphylococcus_phage	7.3e-262	98.9
WP_000665205.1\|1614057_1614348_-	VRR-NUC domain-containing protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
WP_015978074.1\|1614481_1614586_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
WP_115276637.1\|1614688_1617136_-	hypothetical protein	B5WZN5	Staphylococcus_phage	0.0e+00	99.9
WP_000265258.1\|1617188_1617389_-	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000595237.1\|1617456_1617609_-	transcriptional activator RinB	B5WZN3	Staphylococcus_phage	2.6e-19	100.0
WP_000483477.1\|1617601_1617838_-	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
WP_000195806.1\|1617862_1618099_-	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
WP_000185703.1\|1618135_1618672_-	hypothetical protein	S4V978	Staphylococcus_phage	1.0e-94	98.9
WP_000028425.1\|1618664_1618847_-	hypothetical protein	D2JGL7	Staphylococcus_phage	2.6e-26	100.0
WP_001065110.1\|1618836_1619088_-	DUF1024 family protein	W5R8J0	Staphylococcus_phage	4.9e-39	100.0
WP_000132193.1\|1619102_1619345_-	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	5.6e-40	98.8
WP_000235324.1\|1619359_1619560_-	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
WP_000022728.1\|1619562_1619820_-	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
WP_031776133.1\|1619819_1620221_-	phage DNA polymerase	A0A2I6PEL5	Staphylococcus_phage	2.3e-67	99.2
WP_001164629.1\|1620220_1620406_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_001802096.1\|1620418_1622371_-	DNA polymerase	A0A2I6PE86	Staphylococcus_phage	0.0e+00	100.0
WP_000645045.1\|1622438_1622996_-	DUF2815 family protein	A0A2K9VBT2	Staphylococcus_phage	1.8e-97	100.0
WP_115276638.1\|1623021_1624188_-	DUF2800 domain-containing protein	A0A0K1LKE3	Staphylococcus_phage	1.6e-220	99.7
WP_031857745.1\|1624184_1624547_-	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	2.4e-55	99.2
WP_000174994.1\|1624561_1624885_-	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
WP_001285954.1\|1624963_1625125_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124160.1\|1625137_1625401_-	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_031867168.1\|1625425_1625641_-	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	2.7e-30	97.2
WP_001128433.1\|1625695_1626061_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001025401.1\|1626029_1626275_-	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_001001383.1\|1626324_1626543_-	hypothetical protein	B5WZL5	Staphylococcus_phage	7.8e-33	100.0
WP_001148559.1\|1626558_1627335_-	hypothetical protein	M1RZB2	Staphylococcus_phage	1.5e-142	100.0
WP_001030311.1\|1627360_1627588_-	hypothetical protein	B5WZL3	Staphylococcus_phage	3.3e-34	100.0
WP_000801423.1\|1627759_1628374_+	helix-turn-helix domain-containing protein	B5WZL2	Staphylococcus_phage	9.0e-111	100.0
WP_000348133.1\|1628389_1629310_+	exonuclease	B5WZL1	Staphylococcus_phage	2.5e-173	100.0
WP_000705240.1\|1629406_1629589_+	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_072433242.1\|1629625_1629772_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	2.2e-15	93.8
WP_000191463.1\|1629768_1630383_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	2.5e-105	99.5
WP_000264751.1\|1630508_1631714_+\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
WP_115276639.1\|1631756_1633784_-	hypothetical protein	B5WZK7	Staphylococcus_phage	2.0e-114	97.2
WP_001548912.1\|1633776_1634706_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000987769.1\|1634950_1636702_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
1635925:1635942	attR	NA	NA	NA	NA
WP_115276640.1\|1636682_1637408_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.6e-45	43.0

DBSCAN-SWA_10

1693864 : 1702176

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1693864_1694650_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924214.1\|1694775_1695666_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062180.1\|1695675_1697022_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
WP_000683931.1\|1697135_1698236_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624584.1\|1698238_1698916_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1699046_1700153_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217261.1\|1700376_1702176_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0

DBSCAN-SWA_11

1771235 : 1780278

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1771235_1771754_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_115276648.1\|1771775_1774049_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
WP_000749795.1\|1774251_1776531_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1776805_1777066_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1777084_1778224_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019172.1\|1778246_1779272_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1779273_1780278_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_12

1905949 : 1988651

Staphylococcus_phage(93.33%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050548.1\|1905949_1912510_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1
WP_000836465.1\|1912835_1913147_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_154801123.1\|1913168_1915583_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.1
WP_001025061.1\|1915873_1917055_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|1917164_1918118_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1918114_1918678_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1918797_1919199_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1920777_1921605_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1921607_1921727_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1921838_1922840_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1922961_1923426_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159022.1\|1923438_1924620_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_000493892.1\|1924630_1925263_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000384181.1\|1925269_1926301_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.8e-197	99.4
WP_001261677.1\|1926793_1928296_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000221179.1\|1928818_1929133_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989121.1\|1929132_1930425_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_000163235.1\|1930442_1930838_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_001032833.1\|1931132_1931987_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1932262_1932487_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1932685_1933156_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1933268_1933712_+	competence protein ComK	NA	NA	NA	NA
WP_001030465.1\|1933698_1934142_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
WP_001168904.1\|1934437_1935073_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1935512_1936226_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1936485_1936788_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1937043_1937409_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623471.1\|1937405_1937759_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453320.1\|1939841_1940675_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
WP_000366154.1\|1940886_1941795_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
WP_000933822.1\|1941919_1943113_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_115276656.1\|1943483_1945076_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_000093392.1\|1945211_1945697_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
WP_115276709.1\|1946008_1946707_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.0e-122	98.1
WP_000672014.1\|1946711_1947185_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|1947250_1947508_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778523.1\|1947504_1948506_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
WP_000348360.1\|1948510_1949989_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
WP_011443643.1\|1950147_1950603_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_115284617.1\|1951636_1952632_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
WP_000669046.1\|1952707_1953334_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
WP_000627551.1\|1953374_1953719_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
WP_000414205.1\|1953816_1954368_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
WP_000494956.1\|1954585_1955227_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
WP_000809857.1\|1955340_1955526_-	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|1955527_1955704_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1955714_1956098_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1956701_1956845_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001801861.1\|1957047_1957143_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791893.1\|1957265_1957367_+	hypothetical protein	NA	NA	NA	NA
WP_002868972.1\|1957714_1958074_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000195429.1\|1959489_1960662_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000072576.1\|1964906_1966106_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	5.5e-229	99.7
WP_011443644.1\|1966098_1967838_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	4.4e-288	99.4
WP_001791797.1\|1967818_1967953_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|1968017_1968737_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001038759.1\|1968887_1969604_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_011447030.1\|1969705_1969813_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1969761_1970481_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038867.1\|1970601_1971321_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
WP_001039447.1\|1971378_1972101_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_001039423.1\|1972225_1972942_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.0e-125	96.2
WP_001092763.1\|1973905_1974472_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|1974945_1975644_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|1975640_1976402_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1976398_1977091_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1977113_1978487_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1978496_1979015_-	enterotoxin	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_115276657.1\|1979030_1980275_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	2.6e-237	99.8
WP_001092605.1\|1980267_1983261_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
WP_000416756.1\|1983325_1983469_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|1984205_1984349_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_115276658.1\|1984590_1985574_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	6.8e-185	98.8
WP_000473596.1\|1985575_1986511_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_001790220.1\|1987310_1987850_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	2.0e-61	76.8
WP_000206350.1\|1987862_1988651_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_13

2017174 : 2096277

Staphylococcus_phage(85.51%)

capsid,head,portal,integrase,tRNA,plate,transposase,terminase,protease,tail,holin

attL 2087835:2087853|attR 2100434:2100452

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181398.1\|2017174_2017645_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_001789049.1\|2017649_2018792_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_001144055.1\|2018927_2019656_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-36	42.7
WP_000649907.1\|2019642_2021100_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_000063582.1\|2021357_2022419_-	PTS transporter subunit IIC	NA	NA	NA	NA
WP_115276599.1\|2022911_2024231_+\|transposase	ISL3-like element IS1181 family transposase	A0A1S5SBP9	Streptococcus_phage	1.7e-50	33.5
WP_031784974.1\|2024249_2024363_+	hypothetical protein	NA	NA	NA	NA
WP_000110011.1\|2032686_2033133_-	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
WP_000869455.1\|2033229_2034180_-	2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_000939521.1\|2034185_2034641_-	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_001011598.1\|2034721_2036011_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_001236371.1\|2036303_2037398_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_001791878.1\|2037487_2037580_-	hypothetical protein	NA	NA	NA	NA
WP_000597238.1\|2037588_2039325_-	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	1.7e-53	30.4
WP_000251253.1\|2039615_2040158_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000284752.1\|2040459_2041497_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000379098.1\|2041648_2042626_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_000886468.1\|2042886_2043723_-	membrane protein	NA	NA	NA	NA
WP_000535834.1\|2043731_2045249_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_001294033.1\|2045263_2045554_-	YfhH family protein	NA	NA	NA	NA
WP_001124419.1\|2045555_2046374_-	recombination regulator RecX	NA	NA	NA	NA
WP_000830380.1\|2046634_2047444_-	monofunctional peptidoglycan glycosyltransferase SgtB	NA	NA	NA	NA
WP_000163283.1\|2047784_2048300_-	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_001005407.1\|2048430_2048592_-	hypothetical protein	NA	NA	NA	NA
WP_100250272.1\|2048938_2049019_+	hypothetical protein	NA	NA	NA	NA
WP_000180531.1\|2049064_2049748_-	hypothetical protein	A0A0A7S0U2	Clostridium_phage	1.1e-13	28.3
WP_000990948.1\|2049744_2049927_-	hypothetical protein	NA	NA	NA	NA
WP_031924639.1\|2051692_2053147_-	CHAP domain-containing protein	I1W626	Staphylococcus_phage	4.1e-287	99.0
WP_000339141.1\|2053157_2053460_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000466784.1\|2053595_2053895_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000916020.1\|2053940_2054105_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|2054097_2054487_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_115276633.1\|2054486_2055953_-\|plate	BppU family phage baseplate upper protein	A0A2I6PDE3	Staphylococcus_phage	2.0e-257	94.3
WP_000429558.1\|2055952_2057863_-	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_000179858.1\|2057878_2058169_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000384474.1\|2058168_2059752_-	peptidase	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_001190533.1\|2059760_2060585_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_031860857.1\|2060584_2066785_-\|tail	phage tail tape measure protein	U5U762	Staphylococcus_phage	0.0e+00	99.8
WP_000438833.1\|2066798_2066957_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589167.1\|2066998_2067349_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000169127.1\|2067406_2067862_-	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
WP_000807536.1\|2067953_2068595_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_001023802.1\|2068629_2069025_-	DUF3168 domain-containing protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
WP_000110020.1\|2069025_2069427_-	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
WP_000395501.1\|2069423_2069756_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
WP_000050973.1\|2069767_2070046_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142739.1\|2070114_2071278_-\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
WP_115276634.1\|2071289_2072063_-\|protease	Clp protease ClpP	M1TAZ4	Staphylococcus_phage	2.7e-136	99.6
WP_001100669.1\|2072046_2073285_-\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
WP_115276635.1\|2073289_2074981_-\|terminase	terminase large subunit	A0A2I6PE44	Staphylococcus_phage	0.0e+00	99.6
WP_000778932.1\|2074970_2075276_-\|terminase	terminase	A0A2I6PE27	Staphylococcus_phage	2.9e-49	100.0
WP_015978060.1\|2075404_2075719_-	HNH endonuclease	Q4ZCU3	Staphylococcus_virus	2.5e-56	100.0
WP_031883903.1\|2075875_2076313_-	transcriptional regulator	A0A2I6PEB8	Staphylococcus_phage	1.0e-76	100.0
WP_115276660.1\|2076325_2077693_-	DEAD/DEAH box helicase	A0A0K1LKG3	Staphylococcus_phage	8.7e-263	99.1
WP_000665205.1\|2077673_2077964_-	VRR-NUC domain-containing protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
WP_015978074.1\|2078097_2078202_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
WP_115276637.1\|2078304_2080752_-	hypothetical protein	B5WZN5	Staphylococcus_phage	0.0e+00	99.9
WP_000265258.1\|2080804_2081005_-	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000595237.1\|2081072_2081225_-	transcriptional activator RinB	B5WZN3	Staphylococcus_phage	2.6e-19	100.0
WP_000483477.1\|2081217_2081454_-	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
WP_000195806.1\|2081478_2081715_-	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
WP_000185703.1\|2081751_2082288_-	hypothetical protein	S4V978	Staphylococcus_phage	1.0e-94	98.9
WP_000028425.1\|2082280_2082463_-	hypothetical protein	D2JGL7	Staphylococcus_phage	2.6e-26	100.0
WP_001065110.1\|2082452_2082704_-	DUF1024 family protein	W5R8J0	Staphylococcus_phage	4.9e-39	100.0
WP_000177805.1\|2082718_2082967_-	hypothetical protein	A0A0K1LL46	Staphylococcus_phage	3.0e-41	97.6
WP_000111495.1\|2082966_2083221_-	DUF3310 domain-containing protein	A0A2I6PDN8	Staphylococcus_phage	1.8e-41	96.4
WP_000117792.1\|2083220_2083580_-	hypothetical protein	D2JGL0	Staphylococcus_phage	4.5e-62	100.0
WP_001187264.1\|2083580_2083766_-	DUF3113 family protein	D2JGK9	Staphylococcus_phage	7.0e-27	100.0
WP_000401950.1\|2083765_2084173_-	RusA family crossover junction endodeoxyribonuclease	D2JGK8	Staphylococcus_phage	1.7e-73	100.0
WP_001123684.1\|2084182_2084404_-	DUF3269 family protein	Q4ZBL4	Staphylococcus_phage	1.7e-35	100.0
WP_000628839.1\|2084416_2084575_-	hypothetical protein	A0A0H3U301	Staphylococcus_phage	4.5e-22	98.1
WP_114647922.1\|2084571_2085357_-	ATP-binding protein	A0A0H4J332	Staphylococcus_phage	4.2e-145	99.6
WP_115284618.1\|2085369_2086125_-	helix-turn-helix domain-containing protein	A0A1J0MGB2	Staphylococcus_phage	1.9e-78	76.4
WP_000414755.1\|2086189_2086471_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
WP_031928974.1\|2086609_2087284_-	phi PV83 orf 19-like protein	A1KX69	Staphylococcus_virus	1.5e-130	99.6
WP_001099010.1\|2087295_2087739_-	single-stranded DNA-binding protein	A0A2I6PD99	Staphylococcus_phage	3.2e-73	95.9
WP_000840496.1\|2087735_2088386_-	single-stranded DNA-binding protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
2087835:2087853	attL	NA	NA	NA	NA
WP_000999048.1\|2088386_2088923_-	hypothetical protein	A0A2I6PD93	Staphylococcus_phage	1.7e-81	100.0
WP_000291075.1\|2088935_2089196_-	DUF1108 family protein	A0A059T5A3	Staphylococcus_phage	1.2e-43	100.0
WP_000066014.1\|2089287_2089449_-	DUF1270 domain-containing protein	Q4ZAZ7	Staphylococcus_virus	9.5e-20	98.1
WP_000594791.1\|2089441_2089663_-	hypothetical protein	A0A1X9H0Q4	Staphylococcus_phage	3.3e-31	98.6
WP_001803402.1\|2089733_2090387_+	hypothetical protein	Q4ZBF5	Staphylococcus_virus	1.3e-115	99.5
WP_000939499.1\|2090396_2090540_-	hypothetical protein	A0A0H4ITW0	Staphylococcus_phage	5.6e-16	97.9
WP_001148634.1\|2090555_2091308_-	oxidoreductase	A0A0E3T9K5	Staphylococcus_phage	4.8e-138	99.2
WP_000933365.1\|2091309_2091495_-	helix-turn-helix transcriptional regulator	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
WP_000394410.1\|2091940_2092423_+	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
WP_033861758.1\|2092523_2092703_-	hypothetical protein	A0A0H3U490	Staphylococcus_phage	2.2e-25	98.3
WP_115276661.1\|2092717_2093161_-	hypothetical protein	Q6R853	Staphylococcus_virus	5.8e-75	99.3
WP_000213811.1\|2093208_2093421_-	helix-turn-helix transcriptional regulator	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
WP_020807995.1\|2093572_2094304_+	helix-turn-helix transcriptional regulator	S4SVC5	Staphylococcus_phage	6.9e-134	100.0
WP_000392109.1\|2094339_2095020_+	hypothetical protein	A0A2H4PQQ5	Staphylococcus_phage	5.1e-123	100.0
WP_001145721.1\|2095230_2096277_+\|integrase	site-specific integrase	Q4ZE08	Staphylococcus_virus	4.2e-201	100.0
2100434:2100452	attR	NA	NA	NA	NA

DBSCAN-SWA_14

2850205 : 2867730

Streptococcus_phage(100.0%)

integrase

attL 2836991:2837007|attR 2872504:2872520

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2836991:2837007	attL	NA	NA	NA	NA
WP_001291561.1\|2850205_2851423_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|2851504_2851708_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|2852168_2852399_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|2852395_2852818_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_063631289.1\|2853322_2853676_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	3.0e-58	99.1
WP_000336323.1\|2853735_2853903_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_017647393.1\|2854021_2855941_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.4
WP_001791010.1\|2855956_2856073_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_115276699.1\|2856317_2857253_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	5.9e-170	99.4
WP_000769868.1\|2857249_2858251_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_115276711.1\|2858159_2860313_-	YtxH domain-containing protein	A0A1S5SF30	Streptococcus_phage	4.0e-312	93.9
WP_000331160.1\|2860426_2862874_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|2862857_2863364_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|2863338_2863836_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|2863952_2864174_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|2864216_2865422_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|2865444_2865597_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|2865599_2866985_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|2867013_2867400_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|2867415_2867730_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
2872504:2872520	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022908

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection