CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP012216	Campylobacter jejuni strain CJ074CC443 chromosome, complete genome	2 crisprs	cas2,cas1,cas9,csa3,DEDDh,WYL,cas14j	2	7	0	0

1. NZ_CP012216

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP012216_1

• CRISPR_ID: NZ_CP012216_1
• CRISPR_location: 546265-546499
• CRISPR_type: orTypeII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of NZ_CP012216_1

Consensus_repeat	Method
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	PILER-CR
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CRT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CRISPRCasFinder

spacers of NZ_CP012216_1

>1.1|546302|29|NZ_CP012216|PILER-CR,CRT
ATAGAAATTACTACAGCACAAGCTTATAC
>1.2|546368|29|NZ_CP012216|PILER-CR,CRT
CAAAAAACTTGTATTTTTTATCAAAAAAC
>1.3|546434|29|NZ_CP012216|PILER-CR,CRT
TGGAGTTGAAAGAGTTAATAATACCAATA
>1.4|546302|30|NZ_CP012216|CRISPRCasFinder
ATAGAAATTACTACAGCACAAGCTTATACA
>1.5|546368|30|NZ_CP012216|CRISPRCasFinder
CAAAAAACTTGTATTTTTTATCAAAAAACT
>1.6|546434|30|NZ_CP012216|CRISPRCasFinder
TGGAGTTGAAAGAGTTAATAATACCAATAT

CRISPR arrays and Neighbor proteins around NZ_CP012216_1

CRISPR arrays

The CRISPR arrays of NZ_CP012216_1

>merge|NZ_CP012216|1|546265-546499|PILER-CR,CRT,CRISPRCasFinder
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATATAGAAATTACTACAGCACAAGCTTATACAATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATCAAAAAACTTGTATTTTTTATCAAAAAACTATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATTGGAGTTGAAAGAGTTAATAATACCAATATATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>NZ_CP012216|1|1|546265-546499|PILER-CR
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ATAGAAATTACTACAGCACAAGCTTATAC
AATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CAAAAAACTTGTATTTTTTATCAAAAAAC
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TGGAGTTGAAAGAGTTAATAATACCAATA
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>NZ_CP012216|1|1|546265-546499|CRT
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ATAGAAATTACTACAGCACAAGCTTATAC
AATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CAAAAAACTTGTATTTTTTATCAAAAAAC
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TGGAGTTGAAAGAGTTAATAATACCAATA
TATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>NZ_CP012216|1|1|546266-546499|CRISPRCasFinder
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ATAGAAATTACTACAGCACAAGCTTATACA
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CAAAAAACTTGTATTTTTTATCAAAAAACT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TGGAGTTGAAAGAGTTAATAATACCAATAT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012216.1|WP_002888585.1|554241_554991_+|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|234768
NZ_CP012216.1|WP_079263690.1|537481_540286_-|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|239153
NZ_CP012216.1|WP_002888588.1|551114_552569_+|anaerobic-C4-dicarboxylate-transporter-DcuC	unknown	unknown	gnl|CDD|225611
NZ_CP012216.1|WP_002888583.1|555693_556731_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NZ_CP012216.1|WP_002803269.1|540285_540477_-|twin-arginine-translocation-signal-domain-containing-protein	unknown	unknown	gnl|CDD|236534
NZ_CP012216.1|WP_002867229.1|535914_536847_-|formate-dehydrogenase-subunit-gamma	unknown	unknown	gnl|CDD|130645
NZ_CP012216.1|WP_002851546.1|556795_557245_-|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl|CDD|223854
NZ_CP012216.1|WP_002887722.1|542740_544282_+|multicopper-oxidase-CueO	unknown	unknown	gnl|CDD|225043
NZ_CP012216.1|WP_002855377.1|554965_555697_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	unknown	unknown	gnl|CDD|225539
NZ_CP012216.1|WP_002807291.1|544283_544505_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NZ_CP012216.1|WP_002887724.1|541468_542617_-|carboxynorspermidine-decarboxylase	unknown	unknown	gnl|CDD|273414
NZ_CP012216.1|WP_002887719.1|544955_546146_+|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl|CDD|223380
NZ_CP012216.1|WP_002858894.1|553639_554245_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|234620
NZ_CP012216.1|WP_002851264.1|536843_537485_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319893
NZ_CP012216.1|WP_020247128.1|540451_541165_-|hypothetical-protein	unknown	unknown	gnl|CDD|225916
NZ_CP012216.1|WP_002851193.1|547067_547958_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|187851
NZ_CP012216.1|WP_002887720.1|544505_544952_+|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|223391
NZ_CP012216.1|WP_002888587.1|552589_553579_-|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl|CDD|235439
NZ_CP012216.1|WP_070300721.1|547944_550908_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226044
NZ_CP012216.1|WP_002780988.1|546643_547075_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP012216.1|WP_070300721.1|547944_550908_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	0	1178.6	69.9
NZ_CP012216.1|WP_002851193.1|547067_547958_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	1.4e-98	324.1	9.4
NZ_CP012216.1|WP_002780988.1|546643_547075_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	5e-59	192.3	1.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012216.1|WP_002888585.1|554241_554991_+|diaminopimelate-epimerase	gnl|CDD|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	7.83442e-91
NZ_CP012216.1|WP_079263690.1|537481_540286_-|formate-dehydrogenase-subunit-alpha	gnl|CDD|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP012216.1|WP_002888588.1|551114_552569_+|anaerobic-C4-dicarboxylate-transporter-DcuC	gnl|CDD|225611	COG3069, DcuC, C4-dicarboxylate transporter [Energy production and conversion].	6.3934e-72
NZ_CP012216.1|WP_002888583.1|555693_556731_-|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	7.93254e-34
NZ_CP012216.1|WP_002803269.1|540285_540477_-|twin-arginine-translocation-signal-domain-containing-protein	gnl|CDD|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	0.00537271
NZ_CP012216.1|WP_002867229.1|535914_536847_-|formate-dehydrogenase-subunit-gamma	gnl|CDD|130645	TIGR01583, Formate_dehydrogenase_cytochrome_b556_subunit, formate dehydrogenase, gamma subunit. This model represents the gamma chain of the gamma proteobacteria (and Aquifex aolicus) formate dehydrogenase. This subunit is integral to the cytoplasmic membrane, consisting of 4 transmembrane helices, and receives electrons from the beta subunit. The entire E. coli formate dehydrogenase N (nitrate-inducible form) has been crystallized. The gamma subunit contains two cytochromes, heme b(P) and heme b(C) near the periplasmic and cytoplasmic sides of the membrane respectively. The electron acceptor quinone binds at the cytoplasmic heme histidine ligand. NiFe-hydrogenase and thiosulfate reductase contain homologous gamma subunits, and these can be found scoring in the noise of this model. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	5.55833e-86
NZ_CP012216.1|WP_002851546.1|556795_557245_-|DNA-starvation/stationary-phase-protection-protein	gnl|CDD|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.92874e-51
NZ_CP012216.1|WP_002887722.1|542740_544282_+|multicopper-oxidase-CueO	gnl|CDD|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	9.71152e-120
NZ_CP012216.1|WP_002855377.1|554965_555697_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase	gnl|CDD|225539	COG2992, Bax, Uncharacterized FlgJ-related protein [General function prediction only].	1.57422e-98
NZ_CP012216.1|WP_002807291.1|544283_544505_+|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	3.22446e-11
NZ_CP012216.1|WP_002887724.1|541468_542617_-|carboxynorspermidine-decarboxylase	gnl|CDD|273414	TIGR01047, carboxynorspermidine_decarboxylase, carboxynorspermidine decarboxylase. This protein is related to diaminopimelate decarboxylase. It is the last enzyme in norspermidine biosynthesis by an unusual pathway shown in Vibrio alginolyticus. [Central intermediary metabolism, Polyamine biosynthesis].	0
NZ_CP012216.1|WP_002887719.1|544955_546146_+|molybdopterin-molybdotransferase-MoeA	gnl|CDD|223380	COG0303, MoeA, Molybdopterin biosynthesis enzyme [Coenzyme metabolism].	7.93699e-140
NZ_CP012216.1|WP_002858894.1|553639_554245_+|dephospho-CoA-kinase	gnl|CDD|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	1.78546e-68
NZ_CP012216.1|WP_002851264.1|536843_537485_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319893	cd16371, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	6.18245e-57
NZ_CP012216.1|WP_020247128.1|540451_541165_-|hypothetical-protein	gnl|CDD|225916	COG3381, TorD, Uncharacterized component of anaerobic dehydrogenases [General function prediction only].	0.000474392
NZ_CP012216.1|WP_002851193.1|547067_547958_-|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	7.41783e-121
NZ_CP012216.1|WP_002887720.1|544505_544952_+|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	4.04507e-43
NZ_CP012216.1|WP_002888587.1|552589_553579_-|phosphoribosylformylglycinamidine-cyclo-ligase	gnl|CDD|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP012216.1|WP_070300721.1|547944_550908_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl|CDD|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP012216.1|WP_002780988.1|546643_547075_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.96465e-59

Protein sequences

>NZ_CP012216.1|WP_002887719.1|544955_546146_+|molybdopterin-molybdotransferase-MoeA
MLMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFEDQDKPLKILGITPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENICIENDTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTKLNYSEIALLAELGFFHISVFIKPIVGVLSSGSEIKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILVTTGGVSMGDFDFLKKAIKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYAREILNSWLLQPKDYICKAFLQGSYKKKTPYLEFVACNIKFENGRILANLEGKKEGSSAIINNLNNKAALMVAPKECEILENESLVDIIFMP
>NZ_CP012216.1|WP_002887720.1|544505_544952_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MEHFTLYQGSLDISKIYSQWYEFAKDKNCGALLTFCGIVREEGGIEALSFDIYEPLLKKWFDEWQKRVDFDGISLLFAHSIGDVAIHESSYFAGILSKQRKLGLKLLNEFVEDFKASAPIWKYDVINKERIYAKERSTKLCGAGLLKG
>NZ_CP012216.1|WP_002807291.1|544283_544505_+|MoaD/ThiS-family-protein
MVKVEFLGPINKENLELKVKNLKELKEILQKDESLKEWLELCAVSLNDEIIFDENTKLKDGDKIALLPPVCGG
>NZ_CP012216.1|WP_002887722.1|542740_544282_+|multicopper-oxidase-CueO
MNRRNFLKFNALTLASMGVAYANPMHDMHSMHKNHSINHDLDTSFINFAPKNLKLLDPKQFPQGEILKALPLLKNESKEKNIFRATLEIKENHIELIKGKKTLFYTYNGLVPAPKIEVFEGDKLEILVKNKLKEATTIHWHGVPVPPDQDGSPHDPILAGEERIYRFKIPQDSAGTYWYHPHPHYTASKQVFMGLAGAFVIKAKKDALSHLKERDLMISDLRLDENAQIPNNNLNDWLNGREGEFVLINGQFKPQIKLATNERIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKTIYKEELFLSPASRAEVLIDAPKDGNFKLESAYYDRDKMMVKEEPNTLFLANINLKKENVELPKNLKIFKPSEEPKEFKEIIMSEDHMQMHGMMGKSESELKIALASMFLINGKSYDLKRIDLSSKLGVVEDWIVINKSHMDHPFHIHGTQFELISSKLNGKVQKAEFRALRDTINVRPNEELRLRMKQDFKGLRMYHCHILEHEDLGMMGNLEVKE
>NZ_CP012216.1|WP_002887724.1|541468_542617_-|carboxynorspermidine-decarboxylase
MFYEKIQTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLWEAKFAKEYMDKEIHTYSPAFKEDEIGEIASLSHHIVFNSLAQFHKFQAKTQKNSLGLRCNVEFSLAPKELYNPCGRYSRLGIRAKDFENVDLSTIEGLHFHALCEESADALEAVLKAFEEKFGKWIGQMKWVNFGGGHHITKKGYDVEKLIALCKNFSDKYGVQVYLEPGEAVGWQTGNLVASVVDIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNARMLATRENEKISDLKESEFSYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGIRLPNLMLLDRKNELQMIREFSYKDYSLRN
>NZ_CP012216.1|WP_020247128.1|540451_541165_-|hypothetical-protein
MGALMDLEKLRLARSLYYQCLGELFVFSFSEERLSKLQEYLKTMQECLFDENLKSNFDILLKHLDDENSIQAFFKEYDLLFLSLKNSIPTTFSYIEEGFENSNPLLCVRQILVKSKIRRNEKFFKESEDSVGFCLLLMSEFLRQNEDDLAKELFEKVINKSIDEFLGDVFMNKNANLYKEIASIASAFMEFERLCFEVEKPAKINSKKVQNDLSRSEFLRREVNKQRRTREKSQGIS
>NZ_CP012216.1|WP_002803269.1|540285_540477_-|twin-arginine-translocation-signal-domain-containing-protein
MKNRREFLKKSAFALGAAGVLGSTTLALAKDEERKDLVKGKSKKKEVLFQRSANWEKYYIKAE
>NZ_CP012216.1|WP_079263690.1|537481_540286_-|formate-dehydrogenase-subunit-alpha
MSSVGENIKLTRRSFLKMAALSSLATPLLARSETLREASADELKEAYEGSKKVKTVCTACSVGCGIIAEVQNGVWVRQEIAQDHPVSSGGHCCKGSDMIDMVRSHVRLKYPMKKENGEWKRISYEQALSEIGEKLAAYRKENPESVMFLGSAKLNNEQAYYIRKFAAFFGTNNVDHQARIUHSATVAGVANTFGYGAMTNHLGDIQRSKCIIIIGANPAVNHPVGFRHFLKAKEKGAKLIVVDPRFTKSAAKADIYARIRPGTDIAFMYGMLKIIFDEGLEDTKYLDERVFGIDKIREEAAKWTAEEVENVTGISKELLVQITHEVAKNKPTTLIWAMGLTQHTVGTSNTRLAPIVQMVLGNIGKFGGGVNILRGHDNVQGASDMACLSENLPGYYPLNEATWRYYAKIWGVDYEWLLGNFVSKDWMHKTGLSLARWWAAALNGKDGNDAIDNAGTPLKALVVMGNGITSTAQQVKVKEGLEALELLVLADPFVNEAGIIAERKDGIYLLPAATQFETSGSVTATNRSGQWRFKVVDPLYESMEDQEILFELAKKLGFYEDFTKTLRDEKGEIVWPENATREIAKAVRSIGLNGWSPERLKKHTLYWDKFDEVTLEGKDEVAGEYYGLPWPCWSDKHPGSPVLYNTDIEVAKGGMGFRNNFGLEYEGESLLAKNAPLNSPIDTGYPQITKDNIEKVLGITLSAQEKEKMGSTWSYDDSNIIATKCIEKGIVPYGNAKARAVVWTFKDKIPLHREPLHSPRNDLVQKYPSFEDQKALYRVDTKFVSVQQAKDYSKEFPLNLVTARLVNLNGAGMENRASMYLTRLTPEMFCEINPQLAKEQDIKAGDMIWVHSPEGTKIHVRVKVNPGVAKDMIFLPFHFTGVMQGVDLTHNFPEGTKPYASGESANTVTNYGYDIMCQIPETKGGLCRISKDGK
>NZ_CP012216.1|WP_002851264.1|536843_537485_-|4Fe-4S-dicluster-domain-containing-protein
MSKVNFANLEKERLKFFCDNERCIDCNGCAVACDEAHELPIHIRRRRVITLNEGIQGKEVSTSISCMHCDDAPCSIVCPVDCFYIRADGIVLHDKEICIGCGYCLYACPFGAPQFPKDSVFGNKGIMDKCTMCAGGPEATNSEKERELYGQNRIAEGKVPVCAAMCSTKALLVGESSKIEEIYHNRLMNRNYGIPNPSESLEWKIAYTGKERL
>NZ_CP012216.1|WP_002867229.1|535914_536847_-|formate-dehydrogenase-subunit-gamma
MRKVFVTLLLSVVSLFAYGSERMGQDTQIWDFHRITNIPNYDTFGKLWTTLQGEYIATIALIAVIAVLSAFALHYMVIGPKQFSHDGKKIYAFTLFERLFHFIAAISWVILVPTGFVMMFGATFGGGLFVRVCKNLHAFATVLFIISIIPMFLWWIKRMLPASYDIRWMMIVGGYLSKVKRPVPAGKFNFGQKSWYYIAVFGGFLMIITGGFMYFLDFNSTAIQGLFGLTQIELLRISAIVHNFLGIVCAVFFGVHIYMAVFAIKGSIHSMISGYKEEEEVYILHSYWYKELSNKKQIEPSFSYDPNVKI
>NZ_CP012216.1|WP_002780988.1|546643_547075_-|CRISPR-associated-endonuclease-Cas2
MIEDKFMRVLLMFDVPTKSKKEQKLASKFRNNLIKLGYFMLQFSVYMRICKGLSSAKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQLNKKQEKYHQQNLFEF
>NZ_CP012216.1|WP_002851193.1|547067_547958_-|type-II-CRISPR-associated-endonuclease-Cas1
MSYDEAFKTLLISSNAKLNLELNHLVIKQDENIAKLFLKDINIIVLESLQASLSSALFNAFARHKIILLTCDETHSINGIFTPFLGHFQSAKIAKEQINVSAQKKAILWQKIIKNKILNQAFVLKKHNKIEQSNELINLAKKVSLNDSKNIEAVAAALYFKTLFGTSFSRDELCFENSALNYGYAIIRACIIRAVCISGLLPWLGIKHDNIYNSFALCDDLIEVFRASVDDCVLKLKGESEFLSKDDKRALIGNLQSKINFDGQNYPLNRAINHYVANFKNALLYEDELKIVKFDD
>NZ_CP012216.1|WP_070300721.1|547944_550908_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MARILAFDIGISSIGWAFSENDELKDCGVRIFTKAENPKTGESLALPRRLARSARKRLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRALNELLSKQDFARVILHIAKRRGYDDIKNSDDKEKGAILKAIKQNEEKLANYQSVGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFKKQREFGFSFSKKIEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKKLLGLSDDYEFKGEKGTYFIEFKKYKEFIKALGDHSLSQDDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLITPLMLEGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKKYGKVHKINIELAREVGKNYSQRAKIEKEQNENYKAKKDAELECEKLGLKINSKNILKLRLFKEQKEFCAYSGEKIKISDLQDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNQTPFEAFGNDSAKWQKIEVLAKNLPTKKQKRILDKNYKDKEQKDFKDRNLNDTRYIARLVLNYTKDYLDFLPLSDDENTKLNDTQKGSKVHVEAKSGMLTSALRHTWGFSAKDRNNHLHHAIDAVIIAYANNSIVKAFSDFKKEQESNSAELYAKKISELDYKNKRKFFEPFSGFRQKVLDKIDEIFVSKPERKKPSGALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSLYKDSLILIQTKDMQEPELVYFNAFTSSTVSLIVSKHDNKFETLSKNQKILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKNELR
>NZ_CP012216.1|WP_002888588.1|551114_552569_+|anaerobic-C4-dicarboxylate-transporter-DcuC
MPIFMICSTLLAVIVVAYYILKKYNPIFVFFLSGIILLIFAFYITGTPIPKAPSREHASFLNVLLDSYAFITATFKSQLSGVGLIIMSVAGFATYMKHINASAKLAFLANKPLGKIKNKYLILSGTFIVGMALKIVISSYAGLLLLLLACIYPVLISLKIRPITAVCVLSLIALDYGPKDGNSINMADMVGQSDNVVGLFLNYQIYSVIAYVMVIAILIPFYFAWIDKRDKEKGVLNDEVEIPQIIDPKCPTFYILFPWLPVVFLFIAYFFTIKLDVVTANFVSISLVFLVEFARHRNARKLGEDMMVILKAMAEIFISVVSIIIAAGVFAEGIKALGGVNILANAVSSLGTGNFAWFGILLSIAILSFLVYFATVIMGSGIAAFNAFGKLAPDIAKKLGVAPITLVLPIEIASCLGRAASPIAGGIIALAGFAKVAPMDIIKRTTPLLLIAMLVNVLVAFYLAQTNPLPKEQNTTKIELKIQK
>NZ_CP012216.1|WP_002888587.1|552589_553579_-|phosphoribosylformylglycinamidine-cyclo-ligase
MKISYEDAGVSIDNGNAFVEAIKPLVKETFNDNVVGGIGSFAGAFRMPSGFKKPVILGATDGVGTKLRLAIDAKKYDTIGQDLVAMCVNDLICNFATPLFFLDYYATAKLEVEVAKAVVSGIAKGCKMANCALIGGETAEMPGMYVKDDFDLAGFAVGMAEEDEIDRSKFVKNGDILLALPSSGLHSNGYSLARKVLFESLKLKFDDKIEGKNLIDILLEPTRIYVRDFLTLKPYISALAHITGGGLVENLPRVLPRGMGATIRKHHLKTPEIFYTIGQAVEESEMYRSFNMGVGLVMVVDPSNVSKVLENSDAFIIGEICINEGIVLE
>NZ_CP012216.1|WP_002858894.1|553639_554245_+|dephospho-CoA-kinase
MKNAFFVTASIACGKSTFIEIANSLDFKSISADKIAHKILDENALELEKIFSPFSLKNLLTKEKKIDRKILGEIVFNNKEAKKILENFTHPKIRAKILEQIQILDKENKAFFVEIPLFFESGAYENLGKVIVIYTPKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGKM
>NZ_CP012216.1|WP_002888585.1|554241_554991_+|diaminopimelate-epimerase
MKFYKYCASGNDFVITNADRKEDRSTLAKELCNRYEGIGGDGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFAHHINKINPNMSFLTSAGIIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCDTGVPHLVHFCQNLDEFDTILCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFAYKNEELFFEGKVKYCFEANYNFS
>NZ_CP012216.1|WP_002855377.1|554965_555697_+|mannosyl-glycoprotein-endo-beta-N-acetylglucosamidase
MKPIIIFLSLFLIPLFADDLKNGFGEEYYKLDIDQKRQIFFIKMNEMFDQSFKKIEQERAFIEAFFKDAYKTGFRTSNQTNLEKLITIKNKYRIENLYDFAEYKKRIQKIPKSMGIAQALVESATGTSRFAREANNLFGEWTWGEKGLIPDLRHPDKKHKIKIFDSLQDSVYSYVLNLNRHFAYEKFRDARAKFASEGKEITGLEAIKTLDSYSERKGYYINLITKIIKRYNLEKYDTNSNNT
>NZ_CP012216.1|WP_002888583.1|555693_556731_-|ATP-binding-protein
MKVLNFFYENHPKFEVSYERKNQISKPNIIIKGPRFCGKKTLIFNFLSQFKASEILFLDLYDTRFEKQSLERLADFLNENLQIKILCLYNLDFIPNLEKIKIPIILSTNIKDLNINGFEELELDYFDFEEFISVSKKNLPINNLVGLFLQSGRSKFGEKNILLRQSFTLLELEILKYLALNLGQQISISKIFIELKKRLKTSKDSVYQAIKKLENTYVIYTLKHDEKKLQKIYFKDFGLRNNLCISKDFSHLFENLVLSELFKFKEDFFYNKYFNFYSQISKIAYISSPTLDIDLIKLCAKKILPKALELGIFHVIFITLSSEDSFFEQGVKFEVISFDKFSLGF
>NZ_CP012216.1|WP_002851546.1|556795_557245_-|DNA-starvation/stationary-phase-protection-protein
MSVTKQLLQMQADAHHLWVKFHNYHWNVKGLQFFSIHEYTEKAYEEMAELFDSCAERVLQLGEKAITCQKVLMENAKSPKVAKDCFTPLEVIELIKQDYEYLLAEFKKLNEAAEKESDTTTAAFAQENIAKYEKSLWMIGATLQGACKM

Crispr_ID: NZ_CP012216_2

• CRISPR_ID: NZ_CP012216_2
• CRISPR_location: 686028-686116
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP012216_2

Consensus_repeat	Method
TTACCGCTTTCATAATCATTTAAAGCCTT	CRISPRCasFinder

spacers of NZ_CP012216_2

>2.1|686057|31|NZ_CP012216|CRISPRCasFinder
ATGTAGTTCTTGTTTTGTTTCTTGCCAACTT

CRISPR arrays and Neighbor proteins around NZ_CP012216_2

CRISPR arrays

The CRISPR arrays of NZ_CP012216_2

>merge|NZ_CP012216|2|686028-686116|CRISPRCasFinder
TTACCGCTTTCATAATCATTTAAAGCCTTATGTAGTTCTTGTTTTGTTTCTTGCCAACTTTTACCGCTTTCATAATCATTTAAAGCCTT

>NZ_CP012216|2|2|686028-686116|CRISPRCasFinder
TTACCGCTTTCATAATCATTTAAAGCCTT	ATGTAGTTCTTGTTTTGTTTCTTGCCAACTT
TTACCGCTTTCATAATCATTTAAAGCCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP012216.1|WP_002870306.1|687647_687854_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012216.1|WP_002889423.1|686661_687030_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012216.1|WP_002860113.1|692269_692638_-|hypothetical-protein	unknown	unknown	gnl|CDD|374224
NZ_CP012216.1|WP_002870305.1|687169_687397_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP012216.1|WP_002782344.1|685703_685991_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl|CDD|368240
NZ_CP012216.1|WP_020247164.1|692634_692862_-|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl|CDD|377942
NZ_CP012216.1|WP_002888674.1|690439_690733_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012216.1|WP_002858987.1|681289_682408_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226957
NZ_CP012216.1|WP_020247165.1|691229_692084_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012216.1|WP_002888678.1|684751_685168_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP012216.1|WP_002778842.1|677995_678535_+|iron-transporter	unknown	unknown	gnl|CDD|226001
NZ_CP012216.1|WP_002869698.1|690743_690926_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NZ_CP012216.1|WP_002888679.1|684016_684454_-|DUF411-domain-containing-protein	unknown	unknown	gnl|CDD|225564
NZ_CP012216.1|WP_002884226.1|683054_683543_+|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_CP012216.1|WP_002851157.1|683503_684007_+|conjugal-transfer-protein-TraF	unknown	unknown	gnl|CDD|239264
NZ_CP012216.1|WP_002858988.1|682404_683058_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP012216.1|WP_002888685.1|678617_680021_+|DUF2318-domain-containing-protein	unknown	unknown	gnl|CDD|226828
NZ_CP012216.1|WP_070300709.1|694549_695398_-|DNA-ligase	unknown	unknown	gnl|CDD|181662
NZ_CP012216.1|WP_074470802.1|680007_681300_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223650
NZ_CP012216.1|WP_002867529.1|695397_696060_-|glycoprotein-CgpA	unknown	unknown	gnl|CDD|378705

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP012216.1|WP_070300709.1|694549_695398_-|DNA-ligase	gnl|CDD|181662	PRK09125, PRK09125, DNA ligase; Provisional.	1.41866e-145
NZ_CP012216.1|WP_002860113.1|692269_692638_-|hypothetical-protein	gnl|CDD|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	9.52232e-09
NZ_CP012216.1|WP_002782344.1|685703_685991_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl|CDD|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	0.00445178
NZ_CP012216.1|WP_020247164.1|692634_692862_-|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl|CDD|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	5.1907e-07
NZ_CP012216.1|WP_002858987.1|681289_682408_+|ABC-transporter-permease	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	2.9597e-23
NZ_CP012216.1|WP_002778842.1|677995_678535_+|iron-transporter	gnl|CDD|226001	COG3470, Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism].	3.41537e-100
NZ_CP012216.1|WP_002869698.1|690743_690926_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.63564e-07
NZ_CP012216.1|WP_002888679.1|684016_684454_-|DUF411-domain-containing-protein	gnl|CDD|225564	COG3019, COG3019, Predicted metal-binding protein [General function prediction only].	2.13121e-72
NZ_CP012216.1|WP_002884226.1|683054_683543_+|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.92175e-15
NZ_CP012216.1|WP_002851157.1|683503_684007_+|conjugal-transfer-protein-TraF	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.44675e-09
NZ_CP012216.1|WP_002858988.1|682404_683058_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.87069e-106
NZ_CP012216.1|WP_002888685.1|678617_680021_+|DUF2318-domain-containing-protein	gnl|CDD|226828	COG4393, COG4393, Predicted membrane protein [Function unknown].	0
NZ_CP012216.1|WP_074470802.1|680007_681300_+|ABC-transporter-permease	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	3.84182e-18
NZ_CP012216.1|WP_002867529.1|695397_696060_-|glycoprotein-CgpA	gnl|CDD|378705	pfam11741, AMIN, AMIN domain. This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localizes to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localization of periplasmic protein complexes.	6.4868e-06

Protein sequences

>NZ_CP012216.1|WP_002782344.1|685703_685991_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MQILESDLFTNELNIILSFIVRKESIKVKNTFKNDLYKALKKLDFMPYKFRKSLAFDDENVRDFIFKGYVIPYKIDKEKDLIIILGIYKENLPNF
>NZ_CP012216.1|WP_002888678.1|684751_685168_-|hypothetical-protein
MKKLGLVLAALVALNVSAFADLIVINKKDLVPVSASEMQNKYFQESIKSTLTEPLFKKATFYEADIVAKVDPRTYNSTQAIIQKEYSDKSNYVYYKQVLILTSNGKRARLSTLSCEIASFDKKGYLCGGTADHNYSIK
>NZ_CP012216.1|WP_002888679.1|684016_684454_-|DUF411-domain-containing-protein
MKKTILTILFLLTLTQAKEIQVYESPTCGCCDLWADYMKAKGYEVSVHKTNDFLKIKEKMGIKDEYQSCHTGVIEGYAIEGHVPESAIAWLLENKPKDVIGISAPGMPQGSPGMEQGYSEKYPVILMKKDGSYELYGYFIGGKKL
>NZ_CP012216.1|WP_002851157.1|683503_684007_+|conjugal-transfer-protein-TraF
MGIFRIQAYFFALIIALFFVACDSGENFKALNSDKTYNFAYNGFEKSLKLNDKAQNFALVFFTKDCGVCKEQIPILQNLAKNYDFNIFVVLGDANDANDAKAWADEKGLSNLAMFYEKRAAKYLSSAIGEIYGVPVLSFFKEGKMDEKFIGLTPYSILEKEIKKVKS
>NZ_CP012216.1|WP_002884226.1|683054_683543_+|TlpA-family-protein-disulfide-reductase
MKKSLLILSILFLLNACSFENSKDTGKVGEKSAEISAKDTLGKAVKLADDNTSLKVLVFFQNGCPSCLKELPSLDEFIQNHPNKISVYAINSIDNANVVKVLAEQFNFKNVKVLKDDLKITNDRYAVFATPTTIIIKDGMIKDRILGEKPWEFFESKLISLL
>NZ_CP012216.1|WP_002858988.1|682404_683058_+|ABC-transporter-ATP-binding-protein
MMKKELIKINNLNKEFGKVKALNNINLSVYEGEWLAIMGPSGSGKSTLLNILSLMDTPSSGEYILDNENLEQMDEEQKITLRREKIGLVFQQFHLIPYLNALENVMLSQHYHSSVDEEDAKMVLEKVGLSHRLTHLPSQLSGGEQQRVCIARALINNPELLLADEPTGNLDEANEQIVLQTLQKLKNEGKTIVLITHNPDLAKFADRTLILQHGVLK
>NZ_CP012216.1|WP_002858987.1|681289_682408_+|ABC-transporter-permease
MVDKFFLNELFKSISFSYQRLFIIVLSVFIGALTCSAFLNIYFDIDTKLSKELKAYGANVMISPKQDENFISNAEYEKIKENLKARALTPFLYDFLNLGSTSGVVLGTDFKALKITKPFLEVKEGSFSLNDFDENSAFLGVNLAKQLGLKTGNELQIYNPNNGKSIKLTIKGILSSNDEFDSIVLAPLSVVQNLSDRAGINYANAVVYGNFDEVKAKTQAISNEFIDAKPISSVSLSEGLVLGKIKALMFLIILVVLIIVTTSVNTTLSSIVFSRKKEIALRLALGAKKSEIFKLFASECFIVSFFASLIGAFCGIFLANVFGYLIFNSGIDFRFIAVFIALIISLIFAFLAAFFPIKRALKINVCENLKGE
>NZ_CP012216.1|WP_074470802.1|680007_681300_+|ABC-transporter-permease
MMLAKMIFNSIFKNKIQKFLAFLTCFLATLLLSTMLNITLSIGDEVTKQLKSYGSNILVLPKGSSLSIEIGNELYEPLKNKNYLEEKNLYMIKDIYWRNNITALAPFLEGKITIENSQQKALIYGTYFQKAIKIKDDDDFITGIKSLYPYLAVQGEWAKDDSNEIMLGEDFAKNNKLKLGDTIKLIGENNQSKEAKIVGILLHANPKMSNKIIAPLNLAQDLLNKQGLYSSAEVRAFTIPESALSEKVRRMGEEKLDQLEYDKWYCSAYVGSIASQISDGLPGADAKALNAISDAQSLVVKKIQSLMGITCIICLIVASIAISSLMSSEIHRRKKEIGLLKVLGANTFQIYLIFASENLIVALFAALFGFIFGTALSQIISLSIFGYFIDIAFIALPLSFIFGGLIALLGCLLPIKNITQLSAAGVLYGR
>NZ_CP012216.1|WP_002888685.1|678617_680021_+|DUF2318-domain-containing-protein
MSIYFVHFLISVLPLSILMAFITPNKKYIFKSFLVVFLGFLFGYFAFFIAAQFLKTENLIFNFDFVFIGLLLVSFIFYFWKKIEILNFILLGILSFCTALHYYFLSQDFPIFTSSLIDSEGISSLGFIALALLVCILIFFFLKWQKNFNQKTSFMLFLLLILIESDKALANILLTLMRNSIIETHTFLVSFVGKSNYFGVFGIYVYLIFITFLAFLSLKIRKKNISKKQILDINYRKNEAKTSLINRYFSSVFISCVISFCIVLYFFMVSSKPLTIDEPKEILPDKNGKFIFDIALLRDNKLHRFAYISAEGKVIRFFLINKREDKDSPVAVFDACMICGDMGYIKKDGQLICISCNVRIFLPSVGKSGGCNPIPLKYEYDGKKITIDVKDVIAGSNYFSQIKEIEVQDPVSKTKVINTQAPFSYSYKGITYYFSNQNNYEEFKKDPTKYVEENEAQFLIQRRNDVG
>NZ_CP012216.1|WP_002778842.1|677995_678535_+|iron-transporter
MIKKVLSVVAAAAVISTNLFAGEVPIGDPKELNGMEIAAVYLQPIEMEPRGIDLAASLADIHLEADIHALKNNPNGFPEGFWMPYLTIAYELKNTDTGAIKRGTLMPMVADDGPHYGANIAMEKDKKGGFGVGNYELTFYISNPEKQGFGRHVDEETGVGKWFEPFKVDYKFKYTGTPK
>NZ_CP012216.1|WP_002889423.1|686661_687030_-|hypothetical-protein
MEKVDYCRMSCLDGKINAFKYLLDLFLSDLENENDVKTCNMFDNDTSIEYVKDMLMMMLDKIKEIVIDQDNCHHNIDMYASVYHEIIKDELGKEFTPKELKELHKKQEERLLKELLEGSKKK
>NZ_CP012216.1|WP_002870305.1|687169_687397_+|hypothetical-protein
MTRLEFDEKIKQLGLTRKIFADIAKVSYSGISTNWKDDKEIPSWVEPFLYYYEKGLALDELLKILEKYKNKEKLE
>NZ_CP012216.1|WP_002870306.1|687647_687854_+|hypothetical-protein
MTNNDFESILKKCNLSKKEFATLCDLPYPTLMNWVKADKTPNWVKSWLENYIKAQKYNKIKDLIKDDL
>NZ_CP012216.1|WP_002888674.1|690439_690733_-|hypothetical-protein
MNNKQALEYLKSELCFIFNTRFRYFDFEIFNLLEKKIQILQKLPDFEREIKELLVILESNKKLFLKKNTFIKKEQKRQILLNACKATYEALKHKLKP
>NZ_CP012216.1|WP_002869698.1|690743_690926_-|helix-turn-helix-domain-containing-protein
MQDTNKDFLTIQEVITLYSLSKDTQNKYRMQKKIPYIKIGKKIFYEKVKLDEWFKNHTIN
>NZ_CP012216.1|WP_020247165.1|691229_692084_-|hypothetical-protein
MLPSFKADFEVAIKWEKERECQEAINDKIEPYYNIEIEKAKDENYLYDYLCNSWLENPLYFIFQSEECTILNNKIEEQKIVLCDFLLNNDILFNSLKIFNKLSPRERVKERENIIHNLSHFVKFSMEKFLYNTIFKSEIKKTSTQIKKDNEILVKALKILDENLKDENILKNTKIVQYHFYKFCNACRKIPAAEELKNYIFTNRLLSRNIKEYINFYIKLAINKNILFSIDFNNNKNYINACNNNFDDFMFKMQEKYKLNKREVKRKELKNAIIKAFDNYLRYN
>NZ_CP012216.1|WP_002860113.1|692269_692638_-|hypothetical-protein
MKKDINYYLNLPYKINLVKLDDGDYFAQFDDKELNKLVLMAGDGKTPNEAIEDLKNAFACYLEEALAKNEFIPEPIQKDKSKNLAITLKNSLVDEIDFYSKKMGLSRSAFLAVSAKAYIKTL
>NZ_CP012216.1|WP_020247164.1|692634_692862_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MNNKEKLIKELENNPKNASFANIEKLLSWYGYKLVSIRGSHHKFKKDNKSIIVPLHKHIKEFYVKQILKLLKDEK
>NZ_CP012216.1|WP_070300709.1|694549_695398_-|DNA-ligase
MRFVFLICCACLVFANEILLLSKFDKQDFNSKDFNAYLMSEKLDGVRGIWDGKYLKTRQNYKIKTPDFFTKNFPPFAIDGELWLARNKFDEISALIRSGDSNLTLWKEVTYNIFDVPNACEEFQISTCTLKNRLAVLEEYLQKYPSAYIKIIPQIPVENQNNLNQFYESIIKNQGEGIVIRKNLSPYEKGRSKNAMKLKPYDDAECELVGFRKGKGKFENQVGTLLCKMPNGQIIKIGSGLKDEDRKNPPKIGSIVTYKFNGLTKNSLPRFPVFLRIRDENP
>NZ_CP012216.1|WP_002867529.1|695397_696060_-|glycoprotein-CgpA
MKTRILAIFFIFTSLLYADENPFKTDQNITLVAPPEFQKEEVKFNSSARILKSITFNYINLDGSEDKIDLDVNKSIDWHDTYTISRFKSPDPSKVLDVSVTIPEKNSSKQESNSTANVEIPLQVAKIYDFISYAVYKNKIKLNTSDEMITDFSVGNPSKIVIDFRSKMISPTKNIRLSNSIFKRIDFGSHKGYYRLVIYLDGTYNYSIQKDATGYMINLL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP012216.1	1360015-1360043	0	1.0
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP012216.1	1360014-1360043	0	1.0

1. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to position: 1360015-1360043, mismatch: 0, identity: 1.0

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacttgtattttttatcaaaaaac	Protospacer
*****************************

2. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to position: 1360014-1360043, mismatch: 0, identity: 1.0

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacttgtattttttatcaaaaaact	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4758-4786	1	0.966
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4779-4807	2	0.931
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4757-4786	2	0.933
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4778-4807	2	0.933
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4800-4828	5	0.828
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP019232	Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence	7157-7185	5	0.828
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4758-4786	5	0.828
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP019232	Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence	7156-7185	5	0.833
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	216495-216524	5	0.833
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	AP018277	Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome	70567-70595	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MG065650	UNVERIFIED: Campylobacter phage B15, complete genome	45067-45095	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	NC_047776	Escherichia phage ESCO5, complete genome	26221-26249	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	LR597654	Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1	34072-34100	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MH160766	Escherichia phage vB_EcoM-Ro121lw, complete genome	26839-26867	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	NC_020079	Escherichia phage phAPEC8, complete genome	31893-31921	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MN850648	Escherichia phage anhysbys, complete genome	81223-81251	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	LR746137	Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1	19713-19741	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MN850565	Escherichia phage ukendt, complete genome	64332-64360	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	NC_048196	Escherichia phage vB_EcoM_Schickermooser, complete genome	26549-26577	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	NC_047994	Klebsiella phage ZCKP1, complete genome	11010-11038	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	NC_047770	Escherichia phage ESCO13, complete genome	27808-27836	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MN850571	Escherichia phage nepoznato, complete genome	37910-37938	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MH051333	Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome	97145-97173	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MT496970	Escherichia phage Mt1B1_P17, complete genome	123645-123673	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MN850618	Escherichia phage tuntematon, complete genome	129770-129798	6	0.793
NZ_CP012216_1	1.1|546302|29|NZ_CP012216|PILER-CR,CRT	546302-546330	29	MN850598	Escherichia phage nieznany, complete genome	28001-28029	6	0.793
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4737-4765	6	0.793
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4737-4765	6	0.793
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MN693392	Marine virus AFVG_25M95, complete genome	37724-37752	6	0.793
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP031099	Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence	3917-3945	6	0.793
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP014146	Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence	5604-5632	6	0.793
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	33420-33448	6	0.793
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP014521	Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence	3482-3510	6	0.793
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	AP018277	Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome	70567-70596	6	0.8
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4799-4828	6	0.8
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4757-4786	6	0.8
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP014521	Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence	3481-3510	6	0.8
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	MN694478	Marine virus AFVG_250M504, complete genome	19978-20008	6	0.806
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	MN694270	Marine virus AFVG_250M505, complete genome	20095-20125	6	0.806
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	MN694656	Marine virus AFVG_250M501, complete genome	19707-19737	6	0.806
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	MN693919	Marine virus AFVG_250M503, complete genome	16185-16215	6	0.806
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	MN694712	Marine virus AFVG_250M502, complete genome	16183-16213	6	0.806
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP015809	Borrelia mayonii strain MN14-1539 plasmid lp54	135-163	7	0.759
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP015795	Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence	135-163	7	0.759
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	271669-271697	7	0.759
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MG592433	Vibrio phage 1.052.A._10N.286.46.C3, partial genome	21822-21850	7	0.759
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	484569-484597	7	0.759
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	MK075006	Staphylococcus phage phiSP119-3, complete genome	3951-3979	7	0.759
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	MG592587	Vibrio phage 1.216.O._10N.222.55.C12, partial genome	20621-20649	7	0.759
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	216495-216523	7	0.759
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	NC_021277	Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence	4914-4942	7	0.759
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MG065650	UNVERIFIED: Campylobacter phage B15, complete genome	45066-45095	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MN850571	Escherichia phage nepoznato, complete genome	37910-37939	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	NC_047776	Escherichia phage ESCO5, complete genome	26220-26249	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	LR597654	Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1	34071-34100	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MH051333	Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome	97145-97174	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MH160766	Escherichia phage vB_EcoM-Ro121lw, complete genome	26838-26867	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MT496970	Escherichia phage Mt1B1_P17, complete genome	123645-123674	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	NC_020079	Escherichia phage phAPEC8, complete genome	31892-31921	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MN850648	Escherichia phage anhysbys, complete genome	81222-81251	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	LR746137	Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1	19712-19741	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MN850618	Escherichia phage tuntematon, complete genome	129770-129799	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MN850565	Escherichia phage ukendt, complete genome	64331-64360	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	NC_048196	Escherichia phage vB_EcoM_Schickermooser, complete genome	26548-26577	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	NC_047994	Klebsiella phage ZCKP1, complete genome	11009-11038	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	MN850598	Escherichia phage nieznany, complete genome	28001-28030	7	0.767
NZ_CP012216_1	1.4|546302|30|NZ_CP012216|CRISPRCasFinder	546302-546331	30	NC_047770	Escherichia phage ESCO13, complete genome	27807-27836	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG945845	UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome	4736-4765	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG945564	UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome	4736-4765	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MG592433	Vibrio phage 1.052.A._10N.286.46.C3, partial genome	21822-21851	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	484568-484597	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP015809	Borrelia mayonii strain MN14-1539 plasmid lp54	135-164	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP015795	Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence	135-164	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	271669-271698	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MK075006	Staphylococcus phage phiSP119-3, complete genome	3951-3980	7	0.767
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	MN693392	Marine virus AFVG_25M95, complete genome	37724-37753	7	0.767
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	NC_021277	Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence	4913-4942	7	0.767
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	33419-33448	7	0.767
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP031099	Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence	3917-3946	7	0.767
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	NZ_CP014146	Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence	5604-5633	7	0.767
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP017773	Paenibacillus crassostreae strain LPB0068 plasmid pPC03, complete sequence	32644-32674	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040906	Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence	60582-60612	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040906	Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence	94640-94670	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	MN657144	Pedobacter sp. strain ANT_H27B plasmid pA27BH1, complete sequence	51151-51181	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_LR135236	Enterococcus faecium isolate E7067 plasmid 2	87344-87374	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP019209	Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence	189029-189059	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_LR135220	Enterococcus faecium isolate E7040 plasmid 2	87693-87723	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_LR134106	Enterococcus faecium isolate E6043 plasmid 2	87693-87723	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040873	Enterococcus faecium strain DB-1 plasmid punnamed1	31164-31194	7	0.774
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NZ_CP040876	Enterococcus faecium strain DB-1 plasmid punnamed2	93188-93218	7	0.774
NZ_CP012216_1	1.2|546368|29|NZ_CP012216|PILER-CR,CRT	546368-546396	29	KT997865	Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome	2164-2192	8	0.724
NZ_CP012216_1	1.3|546434|29|NZ_CP012216|PILER-CR,CRT	546434-546462	29	MG592583	Vibrio phage 1.213.O._10N.222.54.F10, partial genome	20845-20873	8	0.724
NZ_CP012216_1	1.5|546368|30|NZ_CP012216|CRISPRCasFinder	546368-546397	30	KT997865	Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome	2164-2193	8	0.733
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	MG592587	Vibrio phage 1.216.O._10N.222.55.C12, partial genome	20620-20649	8	0.733
NZ_CP012216_2	2.1|686057|31|NZ_CP012216|CRISPRCasFinder	686057-686087	31	NC_019774	Anabaena cylindrica PCC 7122 plasmid pANACY.04, complete sequence	26535-26565	8	0.742
NZ_CP012216_1	1.6|546434|30|NZ_CP012216|CRISPRCasFinder	546434-546463	30	MG592583	Vibrio phage 1.213.O._10N.222.54.F10, partial genome	20844-20873	9	0.7

1. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 1, identity: 0.966

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacttggattttttatcaaaaaac	Protospacer
*********** *****************

2. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 2, identity: 0.931

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacatggattttttatcaaaaaac	Protospacer
******** ** *****************

3. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 2, identity: 0.933

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacttggattttttatcaaaaaaca	Protospacer
*********** ***************** 

4. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 2, identity: 0.933

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacatggattttttatcaaaaaact	Protospacer
******** ** ******************

5. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 5, identity: 0.828

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aaagtgacttggattttttatcaaaaaac	Protospacer
 **. .***** *****************

6. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP019232 (Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence) position: , mismatch: 5, identity: 0.828

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tgaaaaacttgcattttttataaaaaaat	Protospacer
..*********.********* ******.

7. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 5, identity: 0.828

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aaagtgacttggattttttatcaaaaaac	Protospacer
 **. .***** *****************

8. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP019232 (Bacillus thuringiensis strain YGd22-03 plasmid pYGD36, complete sequence) position: , mismatch: 5, identity: 0.833

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tgaaaaacttgcattttttataaaaaaatt	Protospacer
..*********.********* ******.*

9. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 5, identity: 0.833

tggagttgaaagagttaataatacc-aatat	CRISPR spacer
atgatttgcaagagttaataatacctaata-	Protospacer
  ** *** **************** **** 

10. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to AP018277 (Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
gtagaaatgactacagcacaaggttcggc	Protospacer
.******* ************* **  .*

11. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MG065650 (UNVERIFIED: Campylobacter phage B15, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

12. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to NC_047776 (Escherichia phage ESCO5, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

13. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to LR597654 (Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

14. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MH160766 (Escherichia phage vB_EcoM-Ro121lw, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

15. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to NC_020079 (Escherichia phage phAPEC8, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

16. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MN850648 (Escherichia phage anhysbys, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

17. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to LR746137 (Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

18. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MN850565 (Escherichia phage ukendt, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

19. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to NC_048196 (Escherichia phage vB_EcoM_Schickermooser, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

20. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to NC_047994 (Klebsiella phage ZCKP1, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

21. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to NC_047770 (Escherichia phage ESCO13, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

22. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MN850571 (Escherichia phage nepoznato, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

23. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MH051333 (Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

24. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MT496970 (Escherichia phage Mt1B1_P17, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

25. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MN850618 (Escherichia phage tuntematon, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

26. spacer 1.1|546302|29|NZ_CP012216|PILER-CR,CRT matches to MN850598 (Escherichia phage nieznany, complete genome) position: , mismatch: 6, identity: 0.793

atagaaattactacagcacaagcttatac	CRISPR spacer
atggaaattactacagaacaagcccttat	Protospacer
**.************* ******.. **.

27. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 6, identity: 0.793

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacatggattttttatcaacggcc	Protospacer
******** ** ************ .. *

28. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 6, identity: 0.793

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacatggattttttatcaacggcc	Protospacer
******** ** ************ .. *

29. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MN693392 (Marine virus AFVG_25M95, complete genome) position: , mismatch: 6, identity: 0.793

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caacaaatttgtattttttatcaggatat	Protospacer
*** ***.***************..* *.

30. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP031099 (Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence) position: , mismatch: 6, identity: 0.793

tggagttgaaagagttaataataccaata	CRISPR spacer
tggagttgtaagagttaaaaatataaact	Protospacer
******** ********* ****. **. 

31. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP014146 (Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence) position: , mismatch: 6, identity: 0.793

tggagttgaaagagttaataataccaata	CRISPR spacer
tggagttgtaagagttaaaaatataaact	Protospacer
******** ********* ****. **. 

32. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 6, identity: 0.793

tggagttgaaagagttaataataccaata	CRISPR spacer
tagcagtgaaagtgttaataatagcaata	Protospacer
*.* . ****** ********** *****

33. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP014521 (Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence) position: , mismatch: 6, identity: 0.793

--tggagttgaaagagttaataataccaata	CRISPR spacer
cttcggat--aaagagttaacaataccaata	Protospacer
  * *..*  **********.**********

34. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to AP018277 (Calothrix sp. NIES-4101 plasmid plasmid4 DNA, complete genome) position: , mismatch: 6, identity: 0.8

atagaaattactacagcacaagcttataca	CRISPR spacer
gtagaaatgactacagcacaaggttcggca	Protospacer
.******* ************* **  .**

35. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 6, identity: 0.8

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aaagtgacttggattttttatcaaaaaaca	Protospacer
 **. .***** ***************** 

36. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 6, identity: 0.8

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aaagtgacttggattttttatcaaaaaaca	Protospacer
 **. .***** ***************** 

37. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP014521 (Borrelia anserina Es isolate UTHSCSA plasmid cp5, complete sequence) position: , mismatch: 6, identity: 0.8

--tggagttgaaagagttaataataccaatat	CRISPR spacer
cttcggat--aaagagttaacaataccaatat	Protospacer
  * *..*  **********.***********

38. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to MN694478 (Marine virus AFVG_250M504, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

39. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to MN694270 (Marine virus AFVG_250M505, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

40. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to MN694656 (Marine virus AFVG_250M501, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

41. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to MN693919 (Marine virus AFVG_250M503, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

42. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to MN694712 (Marine virus AFVG_250M502, complete genome) position: , mismatch: 6, identity: 0.806

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
cttttcttcttgttttgttttttgcccactt	Protospacer
 * *  **************.***** ****

43. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP015809 (Borrelia mayonii strain MN14-1539 plasmid lp54) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tctcaaacttctattttttattaaaaaat	Protospacer
.   ****** **********.******.

44. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP015795 (Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tctcaaacttctattttttattaaaaaat	Protospacer
.   ****** **********.******.

45. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aatgaaacttgtattttttattaaaagtt	Protospacer
 * .*****************.****. .

46. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MG592433 (Vibrio phage 1.052.A._10N.286.46.C3, partial genome) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
tcttgaacttgtattttttatcgaaaacc	Protospacer
.   .*****************.**** *

47. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aatgaaacttgtattttttattaaaagtt	Protospacer
 * .*****************.****. .

48. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 7, identity: 0.759

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
aagcaaacttgtcttttttatcaaatgaa	Protospacer
 *. ******** ************ .* 

49. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to MG592587 (Vibrio phage 1.216.O._10N.222.55.C12, partial genome) position: , mismatch: 7, identity: 0.759

tggagttgaaagagttaataataccaata	CRISPR spacer
atatgttgaaagagtcaataataccaagt	Protospacer
  . ***********.***********  

50. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 7, identity: 0.759

tggagttgaaagagttaataataccaata	CRISPR spacer
atgatttgcaagagttaataatacctaat	Protospacer
  ** *** **************** *  

51. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to NC_021277 (Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

tggagttgaaagagttaataataccaata	CRISPR spacer
ttttatcaaaaaagttaataataccaata	Protospacer
*   .*..***.*****************

52. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MG065650 (UNVERIFIED: Campylobacter phage B15, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

53. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MN850571 (Escherichia phage nepoznato, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

54. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to NC_047776 (Escherichia phage ESCO5, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

55. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to LR597654 (Escherichia phage phAPEC8_ev052 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

56. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MH051333 (Escherichia phage vB_EcoM-Ro121c4YLVW, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

57. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MH160766 (Escherichia phage vB_EcoM-Ro121lw, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

58. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MT496970 (Escherichia phage Mt1B1_P17, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

59. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to NC_020079 (Escherichia phage phAPEC8, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

60. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MN850648 (Escherichia phage anhysbys, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

61. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to LR746137 (Escherichia phage vB_EcoM_UP17 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

62. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MN850618 (Escherichia phage tuntematon, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

63. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MN850565 (Escherichia phage ukendt, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

64. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to NC_048196 (Escherichia phage vB_EcoM_Schickermooser, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

65. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to NC_047994 (Klebsiella phage ZCKP1, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

66. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to MN850598 (Escherichia phage nieznany, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

67. spacer 1.4|546302|30|NZ_CP012216|CRISPRCasFinder matches to NC_047770 (Escherichia phage ESCO13, complete genome) position: , mismatch: 7, identity: 0.767

atagaaattactacagcacaagcttataca	CRISPR spacer
atggaaattactacagaacaagcccttatc	Protospacer
**.************* ******.. **. 

68. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG945845 (UNVERIFIED: Microviridae sp. isolate 4961-1502, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacatggattttttatcaacggcca	Protospacer
******** ** ************ .. * 

69. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG945564 (UNVERIFIED: Microviridae sp. isolate 3345-1602, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacatggattttttatcaacggcca	Protospacer
******** ** ************ .. * 

70. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MG592433 (Vibrio phage 1.052.A._10N.286.46.C3, partial genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tcttgaacttgtattttttatcgaaaacct	Protospacer
.   .*****************.**** **

71. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aatgaaacttgtattttttattaaaagttt	Protospacer
 * .*****************.****. .*

72. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP015809 (Borrelia mayonii strain MN14-1539 plasmid lp54) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tctcaaacttctattttttattaaaaaatt	Protospacer
.   ****** **********.******.*

73. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP015795 (Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
tctcaaacttctattttttattaaaaaatt	Protospacer
.   ****** **********.******.*

74. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aatgaaacttgtattttttattaaaagttt	Protospacer
 * .*****************.****. .*

75. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
aagcaaacttgtcttttttatcaaatgaat	Protospacer
 *. ******** ************ .* *

76. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to MN693392 (Marine virus AFVG_25M95, complete genome) position: , mismatch: 7, identity: 0.767

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caacaaatttgtattttttatcaggatata	Protospacer
*** ***.***************..* *. 

77. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to NC_021277 (Fusobacterium nucleatum subsp. animalis 4_8 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
ttttatcaaaaaagttaataataccaatat	Protospacer
*   .*..***.******************

78. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
tagcagtgaaagtgttaataatagcaatac	Protospacer
*.* . ****** ********** *****.

79. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP031099 (Clostridium botulinum strain CFSAN034202 plasmid p2_CFSAN034202, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
tggagttgtaagagttaaaaatataaactc	Protospacer
******** ********* ****. **. .

80. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to NZ_CP014146 (Clostridium botulinum strain CDC_67190 plasmid pNPD12_1, complete sequence) position: , mismatch: 7, identity: 0.767

tggagttgaaagagttaataataccaatat	CRISPR spacer
tggagttgtaagagttaaaaatataaactc	Protospacer
******** ********* ****. **. .

81. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_CP017773 (Paenibacillus crassostreae strain LPB0068 plasmid pPC03, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgc----caactt	CRISPR spacer
ttgtagttcttgttgtgtttgttgcattgca----	Protospacer
 ************* ***** ****    **    

82. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_CP040906 (Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

83. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_CP040906 (Enterococcus faecium strain FB-1 plasmid punnamed, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

84. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to MN657144 (Pedobacter sp. strain ANT_H27B plasmid pA27BH1, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtaggtcttgttttgttttttggtagcat	Protospacer
 ***** *************.*** .*.* *

85. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_LR135236 (Enterococcus faecium isolate E7067 plasmid 2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

86. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_CP019209 (Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

87. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_LR135220 (Enterococcus faecium isolate E7040 plasmid 2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

88. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_LR134106 (Enterococcus faecium isolate E6043 plasmid 2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

89. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_CP040873 (Enterococcus faecium strain DB-1 plasmid punnamed1) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

90. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NZ_CP040876 (Enterococcus faecium strain DB-1 plasmid punnamed2) position: , mismatch: 7, identity: 0.774

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
ctgtatttcttgatttgtttcttgaaagatt	Protospacer
 **** ****** ***********  *. **

91. spacer 1.2|546368|29|NZ_CP012216|PILER-CR,CRT matches to KT997865 (Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome) position: , mismatch: 8, identity: 0.724

caaaaaacttgtattttttatcaaaaaac	CRISPR spacer
caaaaaacttatatttttcatcaggtttt	Protospacer
**********.*******.****..   .

92. spacer 1.3|546434|29|NZ_CP012216|PILER-CR,CRT matches to MG592583 (Vibrio phage 1.213.O._10N.222.54.F10, partial genome) position: , mismatch: 8, identity: 0.724

tggagttgaaagagttaataataccaata	CRISPR spacer
atatgttgaaagagtcaataatcccaagc	Protospacer
  . ***********.****** ****  

93. spacer 1.5|546368|30|NZ_CP012216|CRISPRCasFinder matches to KT997865 (Uncultured Mediterranean phage uvDeep-CGR2-KM22-C255, complete genome) position: , mismatch: 8, identity: 0.733

caaaaaacttgtattttttatcaaaaaact	CRISPR spacer
caaaaaacttatatttttcatcaggttttt	Protospacer
**********.*******.****..   .*

94. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to MG592587 (Vibrio phage 1.216.O._10N.222.55.C12, partial genome) position: , mismatch: 8, identity: 0.733

tggagttgaaagagttaataataccaatat	CRISPR spacer
atatgttgaaagagtcaataataccaagtg	Protospacer
  . ***********.***********   

95. spacer 2.1|686057|31|NZ_CP012216|CRISPRCasFinder matches to NC_019774 (Anabaena cylindrica PCC 7122 plasmid pANACY.04, complete sequence) position: , mismatch: 8, identity: 0.742

atgtagttcttgttttgtttcttgccaactt	CRISPR spacer
gttaagctcttgttttgattcttgccatagt	Protospacer
.*  **.********** *********   *

96. spacer 1.6|546434|30|NZ_CP012216|CRISPRCasFinder matches to MG592583 (Vibrio phage 1.213.O._10N.222.54.F10, partial genome) position: , mismatch: 9, identity: 0.7

tggagttgaaagagttaataataccaatat	CRISPR spacer
atatgttgaaagagtcaataatcccaagcg	Protospacer
  . ***********.****** ****