CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046475	Janibacter melonis strain M714 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP044548	Janibacter melonis strain M714 chromosome, complete genome	13 crisprs	csa3,DinG,cas4,WYL,DEDDh,cas3	5	1	2	0

1. NZ_CP044548

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP044548_1

• CRISPR_ID: NZ_CP044548_1
• CRISPR_location: 70066-70168
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_1

Consensus_repeat	Method
GGGGGACACGCCCCCGGCGGGGTC	CRISPRCasFinder

spacers of NZ_CP044548_1

>1.1|70090|55|NZ_CP044548|CRISPRCasFinder
ACAGGGGGACACGCCCCCGGCGGGGTCGAGGGGGGGGGCGTCGGAGGCGCGACAG

CRISPR arrays and Neighbor proteins around NZ_CP044548_1

CRISPR arrays

The CRISPR arrays of NZ_CP044548_1

>merge|NZ_CP044548|1|70066-70168|CRISPRCasFinder
GGGGGAGAGGCCGCCGGAGGCGCGACAGGGGGACACGCCCCCGGCGGGGTCGAGGGGGGGGGCGTCGGAGGCGCGACAGGGGGGACACGCCCCCGACGGGGTC

>NZ_CP044548|1|1|70066-70168|CRISPRCasFinder
GGGGGAGAGGCCGCCGGAGGCGCG	ACAGGGGGACACGCCCCCGGCGGGGTCGAGGGGGGGGGCGTCGGAGGCGCGACAG
GGGGGACACGCCCCCGACGGGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123091124.1|68628_69207_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NZ_CP044548.2|WP_123091120.1|71896_72163_+|metal-sensitive-transcriptional-regulator	unknown	unknown	gnl|CDD|197385
NZ_CP044548.2|WP_123091131.1|62289_63303_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP044548.2|WP_123091116.1|80145_80784_-|CoA-transferase-subunit-B	unknown	unknown	gnl|CDD|188219
NZ_CP044548.2|WP_123091118.1|76810_77803_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133016
NZ_CP044548.2|WP_123091121.1|70399_71773_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293810
NZ_CP044548.2|WP_123091130.1|63292_63823_-|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NZ_CP044548.2|WP_123091122.1|70178_70358_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_068273459.1|61618_62290_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP044548.2|WP_123091127.1|65561_66017_-|CoA-binding-protein	unknown	unknown	gnl|CDD|379152
NZ_CP044548.2|WP_123091123.1|69245_70052_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP044548.2|WP_123091539.1|72853_74215_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP044548.2|WP_068273482.1|74336_75185_-|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|181133
NZ_CP044548.2|WP_123091125.1|67445_68624_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NZ_CP044548.2|WP_123091126.1|66098_67310_+|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|185017
NZ_CP044548.2|WP_123091129.1|63862_65035_+|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl|CDD|235674
NZ_CP044548.2|WP_123091538.1|75286_76372_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP044548.2|WP_123091128.1|64997_65540_+|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl|CDD|376377
NZ_CP044548.2|WP_123091119.1|72220_72679_-|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NZ_CP044548.2|WP_163562351.1|77875_80002_+|hypothetical-protein	unknown	unknown	gnl|CDD|274252

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123091124.1|68628_69207_-|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.68438e-25
NZ_CP044548.2|WP_123091120.1|71896_72163_+|metal-sensitive-transcriptional-regulator	gnl|CDD|197385	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156. This superfamily includes various transcriptional regulators that respond to stressors including Cu(I), Ni(I), sulfite, and formaldehyde. It includes CsoR (copper-sensitive operon repressor) from Mycobacterium tuberculosis (MtCsoR), Bacillus subtilis (BsCsoR), Thermus thermophilus (TthCsoR), and Staphylococcus aureus (SaCsoR), Mycobacterium tuberculosis RicR (regulated in copper repressor, MtRicR), Escherichia coli RncR (formally known as YohL, nickel and cobalt-sensitive), Alcaligenes xylosoxidans NreA (nickel-sensitive), E. coli FrmR (formally known as YaiN, formaldehyde sensitive), and Staphylococcus aureus CstR (CsoR-like sulfur transferase repressor, NWMN_0026.5, SaCstR). CsoR is Cu(I)-inducible, and regulates the expression of genes involved in copper homeostasis. For example, TthCsoR binds the promoter region of the copZ-csoR-copA operon, and represses expression of these genes, which encode the copper chaperone CopZ, CsoR, and the copper efflux P-type ATPase CopA, respectively. In the presence of excess Cu(I), TthCsoR binds this ion, and is released from the DNA, allowing expression of the downstream genes. TthCsoR also senses other metal ions such as Cu(II), Zn(II), Ag(I), Cd(II) and Ni(II). CsoRs form a homotetramer (dimer of dimers). In the case of MtCsoR, two Cys residues on opposite subunits within each dimer, along with a His residue, bind the Cu(I) ion. These residues are conserved in the majority of members of this superfamily. Exceptions include the functionally uncharacterized Bacillus subtilis YrkD where there is an Asn instead of His (C-N-C), E.coli RcnR where there is a Thr instead of the second Cys (C-H-T), or TthCsoR and E.coli FrmR where there is a His instead of the second Cys and which have an additional N-terminal His (not found in those family members having C-H-C) that may also be involved in metal binding (H-C-H-H). A conserved Tyr and a Glu residue facilitate allosteric regulation of DNA binding. SaCstR regulates genes predicted to function in sulfur metabolism; it is thought that oxidation of the intersubunit Cys pair to a mixture of disulphide and trisulphide linkages by sulfite, results in a reduced affinity of SaCstR for the operator DNA. SaCstR exists as a mixture of oligomeric states, including dimers, tetramers and octamers. The sequence of SaCstR was not available at the time this hierarchy was curated and therefore was not included. Escherichia coli RncR represses expression of the gene encoding the nickel and cobalt-efflux protein RcnA. The gene encoding Alcaligenes xylosoxidans NreA is part of the nre nickel resistance locus located on the pTOM9 plasmid from thisbacteria. Escherichia coli FrmR regulates the formaldehyde degradation frmRAB operon.	2.1315e-23
NZ_CP044548.2|WP_123091131.1|62289_63303_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.53477e-29
NZ_CP044548.2|WP_123091116.1|80145_80784_-|CoA-transferase-subunit-B	gnl|CDD|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	9.76748e-116
NZ_CP044548.2|WP_123091118.1|76810_77803_+|glycosyltransferase-family-2-protein	gnl|CDD|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	7.48168e-97
NZ_CP044548.2|WP_123091121.1|70399_71773_-|MBL-fold-metallo-hydrolase	gnl|CDD|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.58746e-55
NZ_CP044548.2|WP_123091130.1|63292_63823_-|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	3.41665e-23
NZ_CP044548.2|WP_068273459.1|61618_62290_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.06662e-82
NZ_CP044548.2|WP_123091127.1|65561_66017_-|CoA-binding-protein	gnl|CDD|379152	pfam13380, CoA_binding_2, CoA binding domain. This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.	1.01844e-35
NZ_CP044548.2|WP_123091123.1|69245_70052_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	9.26171e-23
NZ_CP044548.2|WP_123091539.1|72853_74215_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.79233e-42
NZ_CP044548.2|WP_068273482.1|74336_75185_-|3-hydroxybutyryl-CoA-dehydrogenase	gnl|CDD|181133	PRK07819, PRK07819, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	1.44845e-173
NZ_CP044548.2|WP_123091125.1|67445_68624_+|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	7.93515e-170
NZ_CP044548.2|WP_123091126.1|66098_67310_+|nucleotide-sugar-dehydrogenase	gnl|CDD|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP044548.2|WP_123091129.1|63862_65035_+|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl|CDD|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	2.6945e-156
NZ_CP044548.2|WP_123091538.1|75286_76372_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	1.30614e-61
NZ_CP044548.2|WP_123091128.1|64997_65540_+|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl|CDD|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	4.06806e-80
NZ_CP044548.2|WP_123091119.1|72220_72679_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.34177e-08
NZ_CP044548.2|WP_163562351.1|77875_80002_+|hypothetical-protein	gnl|CDD|274252	TIGR02669, stage_II_sporulation_protein_D, SpoIID/LytB domain. This model describes a domain found typically in two or three proteins per genome in Cyanobacteria and Firmicutes, and sporadically in other genomes. One member is SpoIID of Bacillus subtilis. Another in B. subtilis is the C-terminal half of LytB, encoded immediately upstream of an amidase, the autolysin LytC, to which its N-terminus is homologous. Gene neighborhoods are not well conserved for members of this family, as many, such as SpoIID, are monocistronic. One early modelling-based study suggests a DNA-binding role for SpoIID, but the function of this domain is unknown. [Unknown function, General].	3.94248e-24

Protein sequences

>NZ_CP044548.2|WP_123091123.1|69245_70052_-|sulfite-exporter-TauE/SafE-family-protein
MPLVVIPLGLLVGLALGALGGGGSVLTVPALVQVLGVEPAVATTSSLVIVGITALLSLPSHHRAGRVRVGQGLTFGLLGTAGSLAGSTAARSVPPAVLMTAFAALMVLVATLMLRRSGRPAGQADASPFEPMITLRPLTCACPRVLQLLAAATLVGLLTGFLGVGGGFVLVPVLVLVLGFTMPVAVGTSLLVVAVNSATALAARLHQGAGDLPWGVVLGFSAVAVVGSVLGSRVGDRVPAGRLSQAFAVLVLVVAAITAVQHVPDLIA
>NZ_CP044548.2|WP_123091124.1|68628_69207_-|rhodanese-like-domain-containing-protein
MTSTDTRPTTLDAAQVRTWLEQPDGPRVLDVRTPGEFAAAHIPGSYNVPLDLVTEHRRKLAEQIDEDVVLVCRSGARATRAGEALSSTGLPHLHVLDGGVQAWEAAGGDLVRGDGTWDLERQVRLVAGGIVLTGVLASTVLPAAKWVSAGIGAGLTGAALTDTCAMGMMLSRLPHNRRHSPELEDVLAQLRG
>NZ_CP044548.2|WP_123091125.1|67445_68624_+|acyl-CoA-dehydrogenase
MSADADFDLFRTSEDHEALREAVRAVSEAKIAPFAAAVDEESRYPQEAHDALVAADFHAAHVAEEHDGVGADALAVCIIIEEVARVCASSSLIPAVNKLGSLPVILGGSPEINARYMPKLASGEGFFSYGLSEREAGSDTAGMRCRATKDGEDWVLRGSKAWITNAGVSEYYTVLAVTDPDGERGRNISAFVVEKSDEGFTFGEKERKLGIKGSPTRELHFDDVRLPGDRIVGAEGEGLKIALRTLDHTRITIGAQAVGIAQGALDHALAYVKERSQFGKAVADFQGIQFMLADMAMELEAARQMVYVAAAKSERGDADLTFFGAAAKAYASDMAMRVTTDAVQLLGGAGYTRDFPLERMMRDAKITQIYEGTNQIQRVVMARQLLQGLPKA
>NZ_CP044548.2|WP_123091126.1|66098_67310_+|nucleotide-sugar-dehydrogenase
MPCPHPQVDRDPVSTRIAVVGTGYVGLSMAVLLAQHNEVVGFDIAPDRVEALNDRRSPIADPEIVDFLAHRELDLRFTLDKAEAYAGAEYVVIATPTDYDPQTNYFNTSTVEGVIADVMEHAPGATMVIKSTIPVGFTAGVRERLGTPDVIFSPEFLREGRALYDNLHPSRIVVGEISDRARRFADLLVEAAEDSDIPVLLTDSTEAEAIKLFANTYLAMRVAYFNELDTFAATHGLNTRQIIEGVGHDPRIGTHYNNPSFGYGGYCLPKDTKQMLANYQDVPQNLMQAIVDSNRTRKDFVAEDVLARSPRVVGIHRLIMKAGSDNFRASSIQGIMKRIKAKGVDVVVFEPELTDDSFYGSRVIRDLDEFKAMSDVIVANRRTDDLADVDDKIYTRDLFGSDS
>NZ_CP044548.2|WP_123091127.1|65561_66017_-|CoA-binding-protein
MSLTHQNDDDLMRELMADPGIWVVVGLSNNTERDAYRVARWLKYELGKGIIPVHPDAEDVDGDTGYASLADIPDGTDVKVVDCFVNSTEVGSVVDQAITHKDRLQIDAIWMQLGVVDAAAADRARAAGLDVVMDTCPKIQARRLRTMGSHR
>NZ_CP044548.2|WP_123091128.1|64997_65540_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MPPTTSKEPSVSEQQPVVGVVMGSDSDWPVMRAASEVLDELGVAHEADVVSAHRMPTAMIEYGQQAAERGLRVIIAGAGGAAHLPGMLASVTPLPVIGVPVPLKYLDGMDSLLSIVQMPAGIPVATVAVGGARNAGLLAARILGAGEGEEAARLRSALVDFAADLEASARAKGEALRAQR
>NZ_CP044548.2|WP_123091129.1|63862_65035_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MTSPRRAPGGFPVVGIIGGGQLARMCAGPAVELGVTLSVLAADAHDSAALVVPSAPVGEHTDLEAVRAFARSCDVVTFDHEQVPAEVLAALEADGATLHPRPSALRYAQDKLAMRERLSRAGIPCPAWAEVRDEGGLLAFADQHGWPVVLKTPRGGYDGRGVLVATQPEDATEWLARAAAAGEPLLVEERVPFVRELAVLVARAPSGQASVWPVVETVQSGGICTEVLAPAPGLTPELAERASDVALGIAAELDVTGVFAVELFELAEGHVVVNELAMRPHNSGHWSMDGATTGQFEQHLRAVLDLPLGSPRARARWTVMANVLGGVDADLYPTYRHVMARDPELKVHLYGKAVRPGRKIGHVNLSGEDLADLRERARHAADYIEGAIRE
>NZ_CP044548.2|WP_123091130.1|63292_63823_-|GtrA-family-protein
MPTTPDTPTGDAPAPGPARTGLRGFVDTIWHEVAKFGVIGLISFVIDLGGMNLLTHTVLEEKPTTARILSGVAATMFAWFGNRSWTFAHRRSRPVAHEVTLFFVVNGIALVISTLTLVISHYVMGLESRLADNISTIFGIGLGTLFRFWAYRRFVFANEPLDVDTSPLAEDEPVSG
>NZ_CP044548.2|WP_123091131.1|62289_63303_+|HAMP-domain-containing-histidine-kinase
MRRRALSATTLPLVVLAVGLGLPLVAALFVAASDPERALQVEPGHLAGWAAVGLAWVALVVAGSAMLARRASERLAEELAGTLGELTQRVRTLGEGGAPAPRSDVAEIDRLAQVITARDVELSRRTATDRDFTADAAHQLRTPLTALLMRLEELAIMDDVDEVHEEAQVAIAQVVRLGGVVEDLRARTRTDEVELPVISLDSVLASIQREYLPAFAAEQRSIRVAGQRGLMVRVRPSDLSQIIGALVENGLKHGAGTVSVVPRRSGPSIVVEARDEGRGIPMAIAPHIFERSVTSQGTGLGLALARDLAERNGGRLQLVQTQPAVFEVYLSDGHVTR
>NZ_CP044548.2|WP_068273459.1|61618_62290_+|response-regulator-transcription-factor
MTRVLLAEDDTAIADPLTRALRREGYDVDAFVDGREALDAVVASGPDLLILDLGLPTLDGLEVCRRVRASGSAVPVLILTARADEVDTVVGLDAGADDYVTKPFRLAELMARVRALLRRTSAEEASAESVLRIDAEARRAWFHGEELALTVKEFEVLSVLVRESGRVVPRDRLMAEVWETEWFGSTKTLDMHISVLRRKLGDDASNPRYITTVRGVGFRFDAG
>NZ_CP044548.2|WP_123091122.1|70178_70358_-|hypothetical-protein
MCRQATCRVCSKTTWAGCGQHVDQVMAGVPRADRCPGHAAEAKTTTPGAGVLSRLLGRG
>NZ_CP044548.2|WP_123091121.1|70399_71773_-|MBL-fold-metallo-hydrolase
MTPQIVTIETPSLGDRSYLAHDGQVAVVVDPQRDIDRVLAAAKEAGVRITDVFETHIHNDYVTGGLALAEQVGARYHVNAEDEVAFEREPIGDGDVVEVSPSMRVRAISTPGHTYTHLSYALESVDETGEVATAVFTGGSLLFGATGRPDLLGADHTHDLVHHQYASAQRLAQELPDQTEVLPTHGFGSFCSAGSTGGSTESTIGVEKRQNPALTQDEEAWVASTLAGLDAYPTYYAHMAPSNSAGPDAPDLSAPETADKETLASRIAAGEWVVDLRTRTAFAAGHVGGTLNFGLDGQLATYLGWLIPWGTPLTLLGESPEQVEQAQRELVRIGIDQLEGAATGTPSDWTDEPLGSFERAVFADLAQVRHHRPVQVLDVRRASEHAGGHVDGALNIPLHELLDRLDEVPAGELWVHCAGGYRASVAASVLAAHGSTVVAVDDSFDEAGPAGLPVVTS
>NZ_CP044548.2|WP_123091120.1|71896_72163_+|metal-sensitive-transcriptional-regulator
MVVLDIEEMGPVINRLRRAQGQIGGVIRLIEEGRDCKDVVTQLAAASRALDRAGFAIVATGLEQCLTAPEGVDPADREAMEKLFLTLA
>NZ_CP044548.2|WP_123091119.1|72220_72679_-|winged-helix-turn-helix-transcriptional-regulator
MTHDGRHEALELETMLLSRYLLPGRRPPKRVRHLERSAYTLLRRLQSQGPMTIAELSEALDLDVSTLNRQTAAMLRCGDLERVPDPDGGVARKFRPTPAGEEHLRHDLGANVDGLRRVVGDWPEEDLDDLVRLLRRFNGDIERLHGRPWPRG
>NZ_CP044548.2|WP_123091539.1|72853_74215_+|MFS-transporter
MQTLVVPLIGDLPQLLGTTATDATWVITATLLAAAVVTPVSGRLGDLYGKRPVMLGCTALLVVGSLVCATASSVVPMIVGRAFQGAAMGLIPLGISVMRDLLPPERLGSSIALMSASLGIGGALGLPAAAAVAEYGSWRGLFWGAAVLALVVAFLVHRFLPASGVTAGGRFDVVGALGLGVGLICVLLPITKGADWGWASGRTLVPLVVGIVVLLVWGAYELRTPEPLVDLRVTARPVVLLTNLASVVVGFAMYAQGLVVPQLLQLPTQTGYGLGQDMLQMGLWMAPGGIVMMLVSPVGARLSHARGPRTTLALGALIVSLGYLSAIALMGSTWGLLVAVCLMSSGVGFAYGAMPALIMGSVPISETASANSVNTLMRSIGTTVSSAVIGVVLSHMTTDLGGVPLPSESGFRVGLLLGAAAAALAAGVALLIPQRAARAAEESIESPVEPARA
>NZ_CP044548.2|WP_068273482.1|74336_75185_-|3-hydroxybutyryl-CoA-dehydrogenase
MQKIGVVGCGLMGAGIAEVCARAGSEVVVVESDDARAESGRARLEKSLRRAQERGKLDDAGAVLERIRVVTDLTELADRDMVVEAILEEESAKVALFKQLDEIVTSPDAILASNTSSIPIMKLATVTKRPSHVLGVHFFNPVPVLKLVELVPSLMTDAQTTERARDYVDNTLGKQAITCQDRAGFVVNSLLIPFILSAIRMYESGFATAEDIDSGLVLGAAHPQGPLALADLIGLDTTMAVAQSLYEEFKEPLYAPPPLLARMVDAGLLGRKTGRGFYTYEQ
>NZ_CP044548.2|WP_123091538.1|75286_76372_-|LCP-family-protein
MPVAGQGQSPRPERPRRPERPATDDRGRPGGPTGPTRTGGGRRRRPLRTAGIVLLCLALVWGGATYWAVSSAWGEVNKVDATPSGERVAEGDGRNVLLVGSDSREGMTREERNRLGTGQAEGKRTDSIIVLHTGGDRPVLLSIPRDSYVEIPGHGMNKINAAYSIGGAKLLGETIEANTGLHMDGYMEIGFGGFAQVVDAVDGVWICVQRDMDDPKAHIDLKKGCQTLDGKTALGYVRARYSDPEGDIGRAKRQRQFLGSLMGEIATPGTLVQPWKLRSLGQQSGGALTVGEDDSMIETGRAFWAIRSVSKGEGDSIVVPISNSNLPTPVGSAVQWDTEKAPQLFDDLNHNRPLSIDPSKG
>NZ_CP044548.2|WP_123091118.1|76810_77803_+|glycosyltransferase-family-2-protein
MPHPLPAVSVVMPVLDEERHLEASVRQVLEQDYEGRVEVVLAVGPSSDRTEELAARLAAADPRVLSVPNPSGRTPDGLNAAIAASSGDVVARVDAHAEIPPSYISTAVRVLDETGADNVGGIMDARGTTPFERAVATAMRSPLGVGGSRFHVGGGAGEADTVYLGVFRREALESVGGYDPHFSRAQDWEMNHRLRQQGRRVWFTPDLVVTYRPRSTVRRLAAQYRGYGRWRRVVARRHPGTANARYLAPPVMVAGTLAATVVGLRWRPALVVPLGYAAAVTVGGWVVAKGETPAVRARVPLAIATMHWAWGIGFLTSPASLAADGDDQTR
>NZ_CP044548.2|WP_163562351.1|77875_80002_+|hypothetical-protein
MISPRTLPALLLAAVLLVPMAAPTSAAPPGRAPATEAAVVVPTQWQISGSGFGHGVGMSQYGAKHLADEGWSARQILAHYYAGTTYDAVPDTQQVAVSLEQSVAQSRLVGRATASGGGTLTLTAGSRTVSAPGGATVVVTRSGSSVVASCSSCSWAPLTGSRITVTTWAARTDLEVSGSLYRYGRLVLTPSAGSGVHAVLWVRLHDEYLDQIREVPWSWPSSALQAQAAAARAYAMRKISGGLRPECACHVTDTVADQVFHPVPTGGELAAWPRWQAAVRATGSSSTGYVPRYGGQVVEALYSSSNGGWSLDGGEVFGAARPYLRSRYDPASLGAENPYRSWTRTISQSSLAAAFGLPDVVRLDLSDRATGHAVATARATSSGGTTATLTGVALRQALGLPSTALRRADARTSGAGAPGLAVAIARSVPTSATSVVLASQYEQDALHALVAQPLAGTLDAPLLLTGRRGLGSATTAELDRRGSRVRTAYVVGGPTTVEDGVLRALRSRGLVVVRLGGSDVDSVAAAVLQQISARRTVRAVAVTTTTGRSAGAAFSGTARRLREPVVVAGSTQLPWRTRAAVGRAGVTSAHLLGGIAHVSEAVEDSLTGAGLSTVRLPGDDDAEVAGRVGEHFVRSVGGTEVVLAPAGSARVLHRAVAGGLGEVVLVGAAPLPGATAAALQRAPSWTRVRAVGTTQEVPTAWLWAARES
>NZ_CP044548.2|WP_123091116.1|80145_80784_-|CoA-transferase-subunit-B
MPLTRVQMAARAAQELADGDYVNLGIGLPTLVPNYVPDDVEIVLQSENGILGVGAYPAEDAVDPDLINAGKETVTLRKGASIFDSATSFGMIRGGKVDAAILGAMQVAANGDIANWMIPGKMVKGMGGAMDLVHGARKVIVLMEHVAKDGSHKIVAECDLPLTGKGVVQRVITDLAVMDLTEDGVVVRELFDISPEDLQDKTGVALTFDLEG

Crispr_ID: NZ_CP044548_2

• CRISPR_ID: NZ_CP044548_2
• CRISPR_location: 263256-263371
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP044548_2

Consensus_repeat	Method
CTCGGGCTCTGAGGAGGGCGCAGGGGAGGT	CRISPRCasFinder

spacers of NZ_CP044548_2

>2.1|263286|56|NZ_CP044548|CRISPRCasFinder
CGTGGGCGAGGAACGAGCCCGCGGCCGAGCCGGAGTCGACGAAGAGCCCGCAACGA

CRISPR arrays and Neighbor proteins around NZ_CP044548_2

CRISPR arrays

The CRISPR arrays of NZ_CP044548_2

>merge|NZ_CP044548|2|263256-263371|CRISPRCasFinder
CTCGGGCTCTGAGGAGGGCGCAGGGGAGGTCGTGGGCGAGGAACGAGCCCGCGGCCGAGCCGGAGTCGACGAAGAGCCCGCAACGACTCGGGCTCTGAGGAGGGCGCAGGGGAGGT

>NZ_CP044548|2|2|263256-263371|CRISPRCasFinder
CTCGGGCTCTGAGGAGGGCGCAGGGGAGGT	CGTGGGCGAGGAACGAGCCCGCGGCCGAGCCGGAGTCGACGAAGAGCCCGCAACGA
CTCGGGCTCTGAGGAGGGCGCAGGGGAGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123090974.1|264982_265336_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP044548.2|WP_123090984.1|252678_256164_-|error-prone-DNA-polymerase	unknown	unknown	gnl|CDD|235553
NZ_CP044548.2|WP_123090980.1|259101_260553_-|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377164
NZ_CP044548.2|WP_123090976.1|263443_264334_-|homocysteine-S-methyltransferase	unknown	unknown	gnl|CDD|224951
NZ_CP044548.2|WP_123090979.1|260719_261361_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123090970.1|269018_270242_-|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl|CDD|238452
NZ_CP044548.2|WP_123090981.1|258556_258988_+|DUF1772-domain-containing-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_068273737.1|265971_266406_+|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|238385
NZ_CP044548.2|WP_123090973.1|265456_265975_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NZ_CP044548.2|WP_123090978.1|261407_262070_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380061
NZ_CP044548.2|WP_068273741.1|267389_267632_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340560
NZ_CP044548.2|WP_123090987.1|248924_250019_+|hypothetical-protein	unknown	unknown	gnl|CDD|226355
NZ_CP044548.2|WP_123090986.1|250049_251099_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238861
NZ_CP044548.2|WP_123090975.1|264485_264986_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176868
NZ_CP044548.2|WP_123090983.1|256185_257757_-|DNA-polymerase-Y-family-protein	unknown	unknown	gnl|CDD|176458
NZ_CP044548.2|WP_123090972.1|267628_268534_-|NTP-transferase-domain-containing-protein	unknown	unknown	gnl|CDD|133000
NZ_CP044548.2|WP_068273739.1|266384_267389_+|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|234672
NZ_CP044548.2|WP_148041522.1|257756_258455_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123090971.1|268530_269022_-|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NZ_CP044548.2|WP_123090985.1|251265_252642_+|APC-family-permease	unknown	unknown	gnl|CDD|129987

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP044548.2|WP_123090974.1|264982_265336_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	5.5e-19	63.4	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123090974.1|264982_265336_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.07931e-16
NZ_CP044548.2|WP_123090984.1|252678_256164_-|error-prone-DNA-polymerase	gnl|CDD|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
NZ_CP044548.2|WP_123090980.1|259101_260553_-|PepSY-domain-containing-protein	gnl|CDD|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	2.68928e-60
NZ_CP044548.2|WP_123090976.1|263443_264334_-|homocysteine-S-methyltransferase	gnl|CDD|224951	COG2040, MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) [Amino acid transport and metabolism].	3.0448e-36
NZ_CP044548.2|WP_123090970.1|269018_270242_-|molybdopterin-molybdotransferase-MoeA	gnl|CDD|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	7.94801e-143
NZ_CP044548.2|WP_068273737.1|265971_266406_+|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|238385	cd00756, MoaE, MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. Moco contains a tricyclic pyranopterin, termed molybdopterin (MPT), which carries the cis-dithiolene group responsible for molybdenum ligation. This dithiolene group is generated by MPT synthase in the second major step in Moco biosynthesis. MPT synthase is a heterotetramer consisting of two large (MoaE) and two small (MoaD) subunits.	9.05831e-32
NZ_CP044548.2|WP_123090973.1|265456_265975_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	1.15371e-58
NZ_CP044548.2|WP_123090978.1|261407_262070_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	1.5595e-34
NZ_CP044548.2|WP_068273741.1|267389_267632_-|MoaD/ThiS-family-protein	gnl|CDD|340560	cd17040, Ubl_MoaD_like, ubiquitin-like (Ubl) domain found in a group of small sulfide carrier proteins. Ubiquitin-like (Ubl) domain found in a group of small sulfide carrier proteins This family includes ThiS, MoaD, CysO, QbsE, and their homologs, which are structurally homologous to ubiquitin (Ub) and may function as the sulfide donor for the biosynthesis of thiamin, molybdopterin, cysteine, thioquinolobactin, and other sulfur-containing natural products. Ub is a protein modifier in eukaryotes that is involved in various cellular processes, including transcriptional regulation, cell cycle control, and DNA repair. Ubiquitination is comprised of a cascade of E1, E2 and E3 enzymes that results in a covalent bond between the C-terminus of Ub and the epsilon-amino group of a substrate lysine. Like Ub, small sulfide carrier proteins in this family are adenylated at a diglycyl C-terminus by specific activating proteins. The adenylated C-terminus is subsequently converted to a thiocarboxylate, serving as the sulfide source. Those activating proteins are diverse and show little sequence similarity. This family also includes the small archaeal modifier protein (SAMP), including SAMP1, SAMP2 and SAMP3, which are Ub-like proteins that function as protein modifiers and are required for the production of sulfur-containing biomolecules in the archaeon Haloferax volcanii. SAMP1 and SAMP2 are involved in sulfur transfer during molybdenum cofactor biosynthesis and tRNA thiolation much like MoaD and Urm1, respectively. They can form covalent conjugates with their protein targets through an isopeptide linkage via their C-terminal diglycine motif in a streamlined archaeal E1-dependent pathway. SAMP2 also forms homo-conjugates through the intermolecular isopeptide bond between the C-terminal Gly and the Lys58 side chain, a feature that likely resembles polyubiquitination. SAMP3 conjugates are dependent on the Ub-activating E1 enzyme homolog of archaea (UbaA) for synthesis and are cleaved by the JAMM/MPN+ domain metalloprotease HvJAMM1.	2.63936e-08
NZ_CP044548.2|WP_123090987.1|248924_250019_+|hypothetical-protein	gnl|CDD|226355	COG3835, CdaR, Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms].	6.60369e-87
NZ_CP044548.2|WP_123090986.1|250049_251099_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	4.08886e-59
NZ_CP044548.2|WP_123090975.1|264485_264986_-|SRPBCC-family-protein	gnl|CDD|176868	cd07826, SRPBCC_CalC_Aha1-like_9, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	4.64588e-57
NZ_CP044548.2|WP_123090983.1|256185_257757_-|DNA-polymerase-Y-family-protein	gnl|CDD|176458	cd03468, PolY_like, DNA Polymerase Y-family. Y-family DNA polymerases are a specialized subset of polymerases that facilitate translesion synthesis (TLS), a process that allows the bypass of a variety of DNA lesions. Unlike replicative polymerases, TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. The active sites of TLS polymerases are large and flexible to allow the accomodation of distorted bases. Expression of Y-family polymerases is often induced by DNA damage and is believed to be highly regulated. TLS is likely induced by the monoubiquitination of the replication clamp PCNA, which provides a scaffold for TLS polymerases to bind in order to access the lesion. Because of their high error rates, TLS polymerases are potential targets for cancer treatment and prevention.	3.71409e-34
NZ_CP044548.2|WP_123090972.1|267628_268534_-|NTP-transferase-domain-containing-protein	gnl|CDD|133000	cd02503, MobA, MobA catalyzes the formation of molybdopterin guanine dinucleotide. The prokaryotic enzyme molybdopterin-guanine dinucleotide biosynthesis protein A (MobA). All mononuclear molybdoenzymes bind molybdenum in complex with an organic cofactor termed molybdopterin (MPT). In many bacteria, including Escherichia coli, molybdopterin can be further modified by attachment of a GMP group to the terminal phosphate of molybdopterin to form molybdopterin guanine dinucleotide (MGD). This GMP attachment step is catalyzed by MobA, by linking a guanosine 5'-phosphate to MPT forming molybdopterin guanine dinucleotide. This reaction requires GTP, MgCl2, and the MPT form of the cofactor. It is a reaction unique to prokaryotes, and therefore may represent a potential drug target.	1.21258e-18
NZ_CP044548.2|WP_068273739.1|266384_267389_+|GTP-3',8-cyclase-MoaA	gnl|CDD|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	7.94106e-173
NZ_CP044548.2|WP_123090971.1|268530_269022_-|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	9.27819e-75
NZ_CP044548.2|WP_123090985.1|251265_252642_+|APC-family-permease	gnl|CDD|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.80327e-42

Protein sequences

>NZ_CP044548.2|WP_123090978.1|261407_262070_-|TetR/AcrR-family-transcriptional-regulator
MAKRLLSVGVAGHAGQVTSTSSATPSSESPTVSRLYEAAADAFGAKGFHATTTRDIASRAGLSPAGVYVHFASKEDLLFQLSREGHTVARDALARAAARSSAPAETLRSMIGAFARWHAEQHQVARIVQYEFRHLSPEHQHEVLTLRREIDAVVRGVVDEGVASGDFEVEDTHAAALALLSLVVDVARWYHPGVQQTPEQIEQTYGALALRLVGASPHPG
>NZ_CP044548.2|WP_123090979.1|260719_261361_-|hypothetical-protein
MTSRGGAIARGSAAAALATAVALCSHVLAGGAVPHVLGVVVPLALAVPACTLLARWRPALPRLGSSVAVSQLLFHTLFSLGAAPGGAGHLEHVRQTGHLGQLGLTAQGEALLTTTTTGAHTMPSSSMWLAHLVAAVVTTAALHRGEEVSRRLHVLALAVAAFLAPPAPVHLARPGTDVRPAPAPRALPTARLVELAQEISRRGPPSGLADSFA
>NZ_CP044548.2|WP_123090980.1|259101_260553_-|PepSY-domain-containing-protein
MSTTTSSTTSPTPPLPSAAPPGRDRPARGWLPQLLLRLHFYAGLLVGPFVLVAALTGAIYALTPSIERVVYAEQLSTDGTGVHRPLSEQVATAQAYTGGERVAAVRPAPDAGSTTRVMFAAPGLGESESRAIFVDPYTNAVRGDLTVYGTSGALPVRTWVDQLHRGLHLGEPGRLYSELAASWLWVVALAGLGLWVRRLRRTRRLREMLLPPRGRAGYRRTRDRHAAVGAWVLVGALGLSATGITWSQLAGERVTDLRAQLGWSAPALDTELSGGTAAAGAHHAGHHGDGGSGEAPRVAPVSFDTVLGAARQAGIDAGQVEVSAPAAEGSAWVVREIRAAYPTEVDTVAVDGDTLEVTDRVTFAEHPFVAKLARWGIDLHIGALFGVANQVALFVLACGIAASVVWGYAMWWRRGTTRPGRVGGRAPARGALARAPWWGLAGVAAVALVVGLALPLVGISLLVFVLIDAGRGLLARRREARTT
>NZ_CP044548.2|WP_123090981.1|258556_258988_+|DUF1772-domain-containing-protein
MSLLEPTPWLVLLAGAHLGFQLTVDRVVYPALVEVGHEQWAGAHAAHSRRITPVVAVIYPPLVLVVAWQLVAHPAVAAGWLAAAGTLVAVVTTALVAAPTHGRLGRGADEQERARLLRRLARADHVRTAGALVAVAGAVLLIA
>NZ_CP044548.2|WP_148041522.1|257756_258455_-|hypothetical-protein
MPEIDIAALRDRVRAMERTTSTREPLSRSAVVDALVPGGLVAGCTYAVHGSHTLLLSLLAGGSAQGRWCGLVGLPDLGVESARGLGLDLERTLAVPSPGETWVETTATLVEALPLVAVRPPHTPSRADVTRLSARLRARSAALVVLLDDAPGEQTRWPGVEASVRVLSQSWTGLADGRGRLLGRELVAEVRPRSAPVRQVALVQRPDGLVGLPGASDDATRRDRRGLLEAAS
>NZ_CP044548.2|WP_123090983.1|256185_257757_-|DNA-polymerase-Y-family-protein
MARAAVRTGTTALATGGRRLVLWCPDWPVRAAVWDAGEGSPLRLSEPIGLVAKGEIHACSAAARGLGVRRGLRVREAQSRCPELLTLTHDPGADERLFASLLPDLEEVVAGVEVVRPGTATLVVDGPARFHGGEVPVGALLCERLVGRGVEDVRAGVADTVFAAEQVARVTDAQDCAALPGEQTADFLAPLPVTALGEPDLADLWRRLGLRTLGDLALLDEADVRARFGERGVRCHRTARGLEDATFLPRRPPATHEESAHFEHALRRAEQVVTGAGAAAQRLVDSLEREHLVCTAVWVEVVTDSGRTLQRRWAHPRFFDAAALLDRLAWTLDAEAPGAPVSEVRLVPDETADVTAVADGLWSDPAGEQVRQAASRIQSALGHDAVGRPEPVGGRGPAERQRLVPWGVAAPRVDDAPWPGHLPAPAPASVYTAPAPAELLDRGGHLVGVTERGAVSASPATVRATPGGPARPVQGWAGPWPADERWWAPDGRRTARLQVVDVTGQAWLLLHADGQWWTEARYD
>NZ_CP044548.2|WP_123090984.1|252678_256164_-|error-prone-DNA-polymerase
MGWHNPQQSWSQLERVLSDTRLTREGLPWPDGGDAPGWSRKREAYTPPPRIDRPRPGSTRPYAELHAHSHFSFLDGASSPQELVEEAVRLGLTGLAVTDHDGLYGAVRLAEAAESHDLGTVFGAELSLGLPEPQAGVADPVGEHLLLLARGPEGYHRLSATLTTGQLAGEKGRPVHDLRRVADELAGHVVVLTGCRKGAVRRALAGPGGGGSPVGPLDLDAAERALRAQQETFGHDAVLVEVSHRGLPGDDHLADALAEVARRAGAPVVATTGAHVARPDAARLAQVVAAVRARRSLDELDGWIAGTGAAHLRSGEEMHRLLGHIPGAVERTVDVAAECAFSLRRATPRLPQHHVPEGHTAMSWLRELVARGMPRRYPHATAAHHERIERELSVIETKDFAGYFVIVHDIAAFAREQGILHQGRGSAANSAVCYALGITAIDSIYYDLPFERFLATTRDEEPDIDLDLDSDRREEVIQWVYARYGRVNAAQVANVITYRPRSAVRDVAKALGHSTGQQDAWSKTIDGWGEVLDGHHDIPAPVVELAEELLGAPRHLGIHSGGMVLTERPVSEVCPIEPARMEDRTVLQWDKDDCAWMGLVKFDLLGLGMLGCIQHTFDHLRHHLGEQWSLERITKEEAAVYDMLCRADSIGVFQVESRAQIGTLTRLLPRRFYDLVVEIALIRPGPIQGGAIHPYIRRRTGAEPVTYLHPKLVPVLERTMGVPLFQEQLMQMAVAVGGCTGDDADLLRRAMGSKRGVEKIASLRERLYEGMAANGITGEVADDIYAKIEAFANFGFAESHALSFGLLVYASSWLKLHYPAAFLAGLLRSQPMGFYSPQTLVADARRHGVEVARPCLLASSVHADLEAGGEVPRWAGEEDLPGEGGPAPAGGYVRPSGMESCLEREQPAIPPFDPDAPEPGAAHRRDAHLRVRLGLSDVTGIDVPTAERVVAEREANGPFVSLVDLTRRVELTAPQVEALATAGAFDALGLTRRQALWGAGAAARERPGQLEVVTPHVGAPELPEMSARESTVADLWSTGIATGDHPIAHERGFLDSMGVLSAQELRTAESDQRVTVAGLVTHRQRPATAQGVTFLSLEDETGMINVICSVGVFRRYRPHSRTASALLVRGTLERRSGAINVVADRLERLPVAAATRSRDFR
>NZ_CP044548.2|WP_123090985.1|251265_252642_+|APC-family-permease
MATTTAPDSSEHDTRLSRSITTTLLFFFIVGDTLGAGIYTLVGTMATDVGGMLWLPLVIALVLALLTAGTYAELITKYPHAGGASRYADRAFDKPFVTFIIGFLMLSSGITTSAALANAFAGDYLASFFGDESLPSSVAIPVRLVFLAVLIAVNLRGVRESLSANVVFTCIEVSGLVLVIVLAAIVFGSGDGDPSRILTPASDTPLLSGAFAASITAFFSFLGFEAAANMAEEVKEPTRAYPRALFGAILTAATVYLLIALGAAIVVDPTTMAESTGPLLEVVKASGIGVPSWLFSAIALVAITNGALLFMVMASRATYGLAEVGLLPSVFGKVLEGRRTPWVAILVVGGATMAMSMIGDVSQLADTTVLLLVLVFISANVSVLVLKKKDSVDHDHFTIPSVVPVLALLASLLLLTQMESTVWLVGAGYLVVGVVLFLVARATRKREVASEGTMEDRV
>NZ_CP044548.2|WP_123090986.1|250049_251099_-|SGNH/GDSL-hydrolase-family-protein
MRPVRTLATLASLTLVSTLAVTDAGAAATGGYVALGDSYSSGTGTRDYLADGTSCQRSARAYPSLIASARGLDLNFRACSGATTADVTSTQLSALSTTTSRVSISVGGNDAGFADVLTECALPAWASSCNAAIDKATTFINGTLPGRLSTLYGSIRAKAPDATVVVVGYPRIFMGEDCNALTWFSPTEQSRLNATADLLNSRIRTAASARGFAFANPTSAFTGHAVCDDVEWLNGLSSPISESYHPNVAGHRSGYTPLVSTPLTGTTVRATSTTVQRADSLAGEQAQRQRGYAEQDRTITPKRMRLPDLDSPRVRRAAERAGVDLGSRRSIDAADRTWSARQSAALVRR
>NZ_CP044548.2|WP_123090987.1|248924_250019_+|hypothetical-protein
MTTLTAALAARIVERTMAVVARNVNVMDERGVILASGQPDRVHTRHEGALLAAEQDRTVVIDDVHELLLRGVQPGVNLPLHHRGAVVGVVGISGPPQEVEVLGDLIRVTAELMVEQAAALEVGRWRERRREDFLVAAAGGLLDEDATTEMAETLGWDLALPRRCTVLRPTGEAHVDLLALQRRVAGLLPEQAGAARVGAVGDQELAVWWPAGPSPVAALGALPGTAVVTGEEHSGGEGVHRAFVSAHESLRVTTLPGGGYDPQDLALLALLVGLRGDWRGAGVAAPWRRLVEQDRHGELQRTVRSWLAHDLDVARCAADLHVHRNTLRLRLSRVETITGLDVRRVPSLLQLYLGPLLDEGPVSS
>NZ_CP044548.2|WP_123090976.1|263443_264334_-|homocysteine-S-methyltransferase
MQHVSDGGLETDLIYHHGVDLPHFAAYVLLRDAHGRDLLRHYYEGYAQVAERHGVGLQLETPTWRASSDWGDLLGDDASALAAANADAVALLREIGEQWSDRVPAVRVVGQLGPRGDGYRPGARVDPDEAAEYHRPQVAALAGAGADHVEVLTLTDVGEAVGVVRAARDVGVPVWVGWTVEVDGRLPGGTSLQEAVEATDTQAAPDAYMVNCAHPQHVAAGLSGPWDRVRGLKVNASERSHEELDAMTSLDPGDPAELAAAHVELERSLPALEVVGGCCGTDATHVGAIWAARTRD
>NZ_CP044548.2|WP_123090975.1|264485_264986_-|SRPBCC-family-protein
MSTAPRGARERATVTTDGPELVVTRTFDAPADLVFEVMTTPEHVRRWWGAGHGEVTVCEIDLREGGAWHFAQRAGSSGDEVSFSGHYRTIERPGHLVHTERFDNLESPYSLVDTTYTESEGRTHLRAVITYDSPETVQMVVESGMEGGLQSSYDAVDDVLAELASR
>NZ_CP044548.2|WP_123090974.1|264982_265336_-|helix-turn-helix-transcriptional-regulator
MADELSTTFAALADPTRRAILTRLGDGEATVSELAQPFAMSLPAISKHLSVLERAGLISKTPDAQRRRCRLEATPLQDATTWLELYREHWERRLDDLGDYLATMSTPSTQGTTQEKP
>NZ_CP044548.2|WP_123090973.1|265456_265975_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MTQPAPTTAPVGAHVLTVSDRSARGEREDLSGPAGREALEGAGFVVTTSVVPDGADSVRDELRRVLAEGVRVVVSTGGTGVGPRDRTPEGTREVLDAELPGVAEAIRAHGATKTPHAVLTRGLAGVVHATADHPGAVVVNLPGSPKAVREGLEVVVPLLAHLLDQLHGGDHR
>NZ_CP044548.2|WP_068273737.1|265971_266406_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MTWRAQIATDPIDLTALMAEVGGPSHGAVSTFVGQVRDHDPEASGEVVSLDYSAHPDAGRVIDDVVSAAVAAGDPDGQAQVVAVHRVGHLEVGDLALVVLVASAHRDLAITLCRDVVEAVKHGVPIWKKQHEVDGSHQWSGLSC
>NZ_CP044548.2|WP_068273739.1|266384_267389_+|GTP-3',8-cyclase-MoaA
MERALVLTDGHGRVHRDLRVSLTDRCNLRCTYCMPAEGMPWLPTPDLLTTDELLRVIEVAVAAGITEVRLTGGEPLLRPDVVDVVRGVAAMSGEHGPVEVSLTSNALRLPKLAQPLADAGLARVNISLDTLRADRFASMTRRDRFEDTMAGIAAADAAGLAPIKINTVLMRGVNDDEAGDLLRWALDHGYELRFIEQMPLDGGHTWQRSEMITAAEILGWLREDFDLVEMPGRGAAPAERFVVDGGPGTVGIIASVTMPFCGACDRLRLTADGQLRSCLFARGETDLRTPLRDGSSEEEVTALLHSCLAGKRPGHGIDEPGFLQPPRPMSAIGG
>NZ_CP044548.2|WP_068273741.1|267389_267632_-|MoaD/ThiS-family-protein
MSVQVRWFGGAAEAAGVEEEQVPEGLLSAVLAATVERHGDAVARVLPRCAVLVDGRNAQGEDPQVPTGSVVDVLPPFAGG
>NZ_CP044548.2|WP_123090972.1|267628_268534_-|NTP-transferase-domain-containing-protein
MSAVEYDVVVVAGGAGSRLGGAVKADLTVDGERLLDRVLAATGSASTRVLVGRGIDAPDDVVRTLEDPPSGGPAAGTDAGLQAVTSPARWTLLLASDLADPAAGIATLLEAAARADEDGEDDVDGICLAGDAEHPQWLFGIHRTAALRGAVESLDTVRNRSMKALLSSLRLTTVAVDPAAVADIDTPTDARTWQAQRPADAPREPRLRGDAATVQRWRQWVEMACEAVAVDPDLVDVAGIHVLTKQVAHGYDRPLAPVSSYVLGLAVGAAQARGEEVDQVALRRAIVATIEQAPPVPEEQS
>NZ_CP044548.2|WP_123090971.1|268530_269022_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MSHPLTHLDEGGHARMVDVTEKSPTVRAATAAGSVRVAPEVVALLRDGAVPKGDVLAVARVAGIQAAKKTPELLPLAHVIGVHGCTVDLTITDTGVDVVATVRTADRTGVEMEALTSVSVAALAVVDMVKGVDRTARITDIRVLSKQGGRSGSWTRPETQDHA
>NZ_CP044548.2|WP_123090970.1|269018_270242_-|molybdopterin-molybdotransferase-MoeA
MSTTRELLTLEQYVAEVLRLVPGPTPVEVVALDDAHGRVLAGAVTARGQVPAFANSAMDGYAVRWADVADAPVELAVVGEVPAGSPHDPAIGPGECVRIMTGAPVPGDADTIVPVELTDGGEQRVHVTAAPERGQGAHVRGAGEDLQAGDLVAEPGTTLTARVLSSVAAAGHAEVPVRRRPVVAVAATGDELVAPGGELGRGQVYESNATHLAATAREQGADVVVPPTVRDDAALVVRALDELAAQADVVVLTGGASVGAYDVARDVLTEHAGATYRHVRVQPGKPQGWALWQGTPVVALPGNPVSAAISFEVVVRPLLDALLGRAPRPTTHAVAATGWRSPPGRRQLVPVRITQGEDLRPLATPSHRRGSASHMVTSLAGADALAEVPEETTEVAPGDLLTIRSLA

Crispr_ID: NZ_CP044548_3

• CRISPR_ID: NZ_CP044548_3
• CRISPR_location: 770345-770429
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_3

Consensus_repeat	Method
AGCTTTCCCGCCCAGGGCGGGAA	CRISPRCasFinder

spacers of NZ_CP044548_3

>3.1|770368|39|NZ_CP044548|CRISPRCasFinder
CATGCGACCTCGGGAAGGAACATTTCTTTCCCGAGGTCG

CRISPR arrays and Neighbor proteins around NZ_CP044548_3

CRISPR arrays

The CRISPR arrays of NZ_CP044548_3

>merge|NZ_CP044548|3|770345-770429|CRISPRCasFinder
AGCTTTCCCGCCCAGGGCGGGAACATGCGACCTCGGGAAGGAACATTTCTTTCCCGAGGTCGAGCTTTCCCGCCCTGGGCGGGAA

>NZ_CP044548|3|3|770345-770429|CRISPRCasFinder
AGCTTTCCCGCCCAGGGCGGGAA	CATGCGACCTCGGGAAGGAACATTTCTTTCCCGAGGTCG
AGCTTTCCCGCCCTGGGCGGGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123091727.1|762759_763506_+|phosphoadenylyl-sulfate-reductase	unknown	unknown	gnl|CDD|234997
NZ_CP044548.2|WP_123091732.1|768787_769510_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|273824
NZ_CP044548.2|WP_123091975.1|770434_771109_-|phosphoserine-phosphatase-SerB	unknown	unknown	gnl|CDD|319803
NZ_CP044548.2|WP_123091735.1|772503_773694_+|glycogen-synthase	unknown	unknown	gnl|CDD|273997
NZ_CP044548.2|WP_123091741.1|777931_778645_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP044548.2|WP_123091973.1|765356_767228_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP044548.2|WP_123091974.1|767295_768135_-|SURF1-family-protein	unknown	unknown	gnl|CDD|119401
NZ_CP044548.2|WP_123091742.1|778654_779461_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP044548.2|WP_123091731.1|768358_768637_-|DUF3099-domain-containing-protein	unknown	unknown	gnl|CDD|378630
NZ_CP044548.2|WP_123091728.1|763502_764606_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|381169
NZ_CP044548.2|WP_123091737.1|774484_775270_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224044
NZ_CP044548.2|WP_123091738.1|775309_775762_+|NfeD-family-protein	unknown	unknown	gnl|CDD|224501
NZ_CP044548.2|WP_123091729.1|764602_765286_+|hypothetical-protein	unknown	unknown	gnl|CDD|239509
NZ_CP044548.2|WP_123091734.1|771186_772437_-|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl|CDD|234846
NZ_CP044548.2|WP_123091730.1|768131_768362_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123091736.1|773707_774454_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123091726.1|762580_762763_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123091740.1|777147_777918_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP044548.2|WP_123091733.1|769567_770323_+|enoyl-ACP-reductase-FabI	unknown	unknown	gnl|CDD|236124
NZ_CP044548.2|WP_123091739.1|775823_777086_+|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl|CDD|223407

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123091727.1|762759_763506_+|phosphoadenylyl-sulfate-reductase	gnl|CDD|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	3.93322e-92
NZ_CP044548.2|WP_123091732.1|768787_769510_+|SDR-family-oxidoreductase	gnl|CDD|273824	TIGR01830, 3-oxoacyl-_reductase_FabG, 3-oxoacyl-(acyl-carrier-protein) reductase. This model represents 3-oxoacyl-[ACP] reductase, also called 3-ketoacyl-acyl carrier protein reductase, an enzyme of fatty acid biosynthesis. [Fatty acid and phospholipid metabolism, Biosynthesis].	8.99162e-106
NZ_CP044548.2|WP_123091975.1|770434_771109_-|phosphoserine-phosphatase-SerB	gnl|CDD|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	7.47075e-87
NZ_CP044548.2|WP_123091735.1|772503_773694_+|glycogen-synthase	gnl|CDD|273997	TIGR02149, glgA_Coryne, glycogen synthase, Corynebacterium family. This model describes Corynebacterium glutamicum GlgA and closely related proteins in several other species. This enzyme is required for glycogen biosynthesis and appears to replace the distantly related TIGR02095 family of ADP-glucose type glycogen synthase in Corynebacterium glutamicum, Mycobacterium tuberculosis, Bifidobacterium longum, and Streptomyces coelicolor. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP044548.2|WP_123091741.1|777931_778645_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.28619e-08
NZ_CP044548.2|WP_123091973.1|765356_767228_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.66902e-161
NZ_CP044548.2|WP_123091974.1|767295_768135_-|SURF1-family-protein	gnl|CDD|119401	cd06662, SURF1, SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring complex of the respiratory chain, is an assemblage of nuclear and mitochondrially-encoded subunits. Its assembly is mediated by nuclear encoded assembly factors, one of which is Surf1/Shy1. Mutations in human Surf1 are a major cause of Leigh syndrome, a severe neurodegenerative disorder.	1.02768e-40
NZ_CP044548.2|WP_123091742.1|778654_779461_+|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.31899e-57
NZ_CP044548.2|WP_123091731.1|768358_768637_-|DUF3099-domain-containing-protein	gnl|CDD|378630	pfam11298, DUF3099, Protein of unknown function (DUF3099). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	2.13648e-20
NZ_CP044548.2|WP_123091728.1|763502_764606_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	2.42349e-96
NZ_CP044548.2|WP_123091737.1|774484_775270_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.90236e-90
NZ_CP044548.2|WP_123091738.1|775309_775762_+|NfeD-family-protein	gnl|CDD|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	2.3427e-18
NZ_CP044548.2|WP_123091729.1|764602_765286_+|hypothetical-protein	gnl|CDD|239509	cd03416, CbiX_SirB_N, Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase, responsible for the chelation of Co2+ into sirohydrochlorin, an important step in the vitamin B12 biosynthetic pathway. CbiX often contains a C-terminal histidine-rich region that may be important for metal delivery and/or storage, and may also contain an iron-sulfur center. Both are found in a wide range of bacteria. This subgroup also contains single domain proteins from archaea and bacteria which may represent the ancestral form of class II chelatases before domain duplication occurred.	1.4896e-17
NZ_CP044548.2|WP_123091734.1|771186_772437_-|glucose-1-phosphate-adenylyltransferase	gnl|CDD|234846	PRK00844, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NZ_CP044548.2|WP_123091740.1|777147_777918_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.19666e-22
NZ_CP044548.2|WP_123091733.1|769567_770323_+|enoyl-ACP-reductase-FabI	gnl|CDD|236124	PRK07889, PRK07889, enoyl-[acyl-carrier-protein] reductase FabI.	1.80352e-171
NZ_CP044548.2|WP_123091739.1|775823_777086_+|SPFH/Band-7/PHB-domain-protein	gnl|CDD|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	1.13886e-70

Protein sequences

>NZ_CP044548.2|WP_123091733.1|769567_770323_+|enoyl-ACP-reductase-FabI
MLTGKTFLITGVLMESSIAFHVAKIAQEQGAKVILTSFGRTMRITQTIARRLPETAPVIELDVTDQEHLDSLAERLGEHCEQLDGVLHSIGFAPEGAFSFLEAGWEDVSTALHVSAYSLKALAVAALPRMSAGGSVVGLTFDASFAWPVYDWMGVAKAAFESTNRYLARDLGPKGVRCNLVAAGPIRTTAAKSIPGFEQFEESWDSRAPLGWDVGDPVPTARACVALLSDWFPATTGEILHVDGGVHAMGL
>NZ_CP044548.2|WP_123091732.1|768787_769510_+|SDR-family-oxidoreductase
MAATPTPRRVLVTGGNRGIGRAVADRLVADGHHVVVTSRSGDVVEGLDVVACEVGDSSSVDAAFTAAEEILGGSVEVLVANAGITHDTLLMRMTEDDFSRVVDTNLTGAFRCVRRATTGMVKGRFGRVVLVSSVVGLYGSPGQVNYAASKAGLVGMARSITRELGARGITANVVAPGFVETDMTAELAEKTQAEYKAAIPARRFAQPGEIAGAVSFLASDDAGYISGAVIPVDGGLGMGH
>NZ_CP044548.2|WP_123091731.1|768358_768637_-|DUF3099-domain-containing-protein
MPHAPDVASVTSAAPPASVDRRRRTRNYLLTMALRTACFVMAYLFEGWLRWTCVVLAVLLPYVAVVIANAVGPRRGTPMSSAGPVDRAQITR
>NZ_CP044548.2|WP_123091730.1|768131_768362_-|hypothetical-protein
MSLADEPLVCSAKGCRRAAVRAVVWRNPRLHDETRRKVWLACEEHTSTLHEHLSVRGFPVRLAELDAIPPEGHPWA
>NZ_CP044548.2|WP_123091974.1|767295_768135_-|SURF1-family-protein
MSITEHRAVLRRAVAPAWLRWWLVAVLVAVACYYLGQWQWGRYEDKAARADRIERHYAAPAQPVSEVLGASPVPLEREWTRVQARGEYLDGDLLARNRPRDGVYGYEVLSRLELDDGSVLVVDRGWIPNSEQGAEVRPDVPAPPSGQVEVTGWVRQGERSLDRDPIPGQLSSINLAEASQEWGDQALLGGYVVRQQEQPAADPTPLDLDAPDTGTGPHMAYAIQWWLVIPAVFVLIWFFVRREERDAAPALEDEQVPDETAPAPPPRRAKVRIWDEEDG
>NZ_CP044548.2|WP_123091973.1|765356_767228_+|ABC-transporter-ATP-binding-protein
MTSWQLMRSMTQDAGATRSPLPPGTGRRVLSYARGMSGTIAAFLVLVALSSSTVVAAPLILGRLVDDGITPQRRDVVVGLALLVALVAVVEAVTTIAQRWYSARIGEGLIYRLRTQVFEHVLAQPIAFFTRAQTGALVTRLNTDVIGAQSAFTSVLSSVVSNVISLVLIIGAMALLSWQLTLASLALVPFFILPARWMGRRLAVLTAEQMGHNADLGTQMTERFNVGGALLVKIFGHPEHELAEYDSRASRVRDIGVVIAVNRALFFVLLTFIAALATAMVYGVGGIMAVDGTLSVGTLLALAALLGRLYGPLTAISNVRVDILTTLVSFARLFEVLDLRPSIQEREGARDLPQGDALDVELDDVHFAYPSADEVSLASLEARATGDRAGSGEILRGVSLDAPAGTLTALVGPSGAGKTTLTALVARLYDPTAGAVRVGGVDLRDATLRSLHDSVAVVTQDAHLFHDTIRGNLLFVRPEATDEQMEQALRAAQIWHLVESLPSGLDTVVGDRGHRLSGGEKQRLAIARLLLKAPAVVVLDEATAHLDSESEAAVQRALEIALAGRTSIVIAHRLSTIRGADQILVVDGGEIAERGTHHELLARGGLYADLYRTQFAEADAPVG
>NZ_CP044548.2|WP_123091729.1|764602_765286_+|hypothetical-protein
MTTVLLAHGSPDPRHRQGIEAVADGLRSARPGTPVRLAYLETDEPSAAVLGRELTGEVVVVPMLITPAYHARTDVPRAARELATGGAQVRVTDPLAPHPLLLDAVVERLASAGHAPDPGTDVMLVAGGSSDGTARRSLDELLVDHPRPGWGRWRGTTLREPEVVAEAVGQAAQAGHRLVVLAFTLAEGVLHDAAERLAGEHGADFVRGGLGRTRSVVELVALRATPA
>NZ_CP044548.2|WP_123091728.1|763502_764606_+|uroporphyrinogen-III-C-methyltransferase
MSAGGYRLGLDLTDRLVLVVGGGPAAVREAEGCLVAGARVLLLAPEVDPGLAGRAGLTWRAAPFDPADLSGPDRVWLVHAATGDPATDGAVARAAEEAGVWCVRAEHQPRAARGHGDGRVGRVALVGGGPGAPDLITVRGARLLAQADVVVTDRLGPVDLLDDLPAHVEVVDVGKHRDRHPVPQDRINEILVDRARRGLDVVRLKGGDPFVLGRGGEEALHCAAHGIAVEVVPGITSAISVPAAVGIPVTHRGITTSFVVASAHEGAGPSLDGLRDAPQDATLVLLMGVTALGRTAADLVAAGRAPGTPVAIVERGWMLGQRVTRTTLSRAAADAEAEGVRAPAVVVVGEVVTVPEQAARLLAGSTA
>NZ_CP044548.2|WP_123091727.1|762759_763506_+|phosphoadenylyl-sulfate-reductase
MTEPVRTPEPPARSAADEAQHRFAALEAERGDTYEGRVELARETLRWAHETYGAGLTTASSMGDEVLVHLLGTTLTGADVFFLDTGYHFAETLGTRDAYEAMLPVQIRTILPRLTVAEQDAEHGPRLHDRDPNACCAMRKVEPMNRALEGYDAWVTGMRREDAPTRSDIELVGWDDRRGMAKLNPIAGWTQDDVDRYVDEHGVFLNPLRQSGYASIGCAPCTRPVAEGEDARAGRWSGTDKVECGLHT
>NZ_CP044548.2|WP_123091726.1|762580_762763_+|hypothetical-protein
MSRVTPVYHCPFCAEQDLRPAPEPLGAWVCGSCVRVFSVTLHGSDRDLAAPLSSTPEEPS
>NZ_CP044548.2|WP_123091975.1|770434_771109_-|phosphoserine-phosphatase-SerB
MLLVMDVDSTLIQAEVIELVAEHAGTRDEVAAVTEAAMRGELDFAQSLHARVATLAGLPVSVLDDVRAAVPLTPGARTLVDAFRERGWPVGLVSGGFVEVVEPLAAALGIEHVRANRLEAEGGRLTGRVDGPVVDREAKADFLRELAAVSGVPIERTVAVGDGANDLDMVAAAGTGVAFCAKPALRDAADVRVDEPDLALVLDALGLTAERSPDDEGSLPLRRV
>NZ_CP044548.2|WP_123091734.1|771186_772437_-|glucose-1-phosphate-adenylyltransferase
MSRRGAPKVLVIVLAGGEGKRLMPLTADRAKPAVPFGGNYRLIDYALSNVINSGYRQVVVLTQYKSHSLDRHVSQAWRMSTMLGSYVAAIPAQQRLDKSWYTGSANAIYQSLNAIRDERPDIVVVVGADHVYRMDFSQMVDQHLESGAGCTVAAIRQPIGLSDQFGVIEVDAADPTRISAFREKPTDAIGLPDSPGEVYASMGNYVFTTDALVDAVTRDDTVEGSKHDMGGDIVPDFVSRQDAYAYDFNANEVPGATDRDRAYWRDVGTLDSYYEAHMDLTSIHPIFNLYNYDWPIYTHQQPHPPAKFVHGDQGRFGEALNSCVAPGVVVSGARVNNSILSPQVHLHSYTTVEDSVLLDRVDVGRHVQLQRVIVDKDVTIPEGTKIGVDREHDEARGFVVTESGLTVVGKGQVVTP
>NZ_CP044548.2|WP_123091735.1|772503_773694_+|glycogen-synthase
MRVDILSKEYPPAIYGGAGVHVAELTRALRGRGDLDVQVRCFGDPRDEGGTTGYPDLAELSGANPALQTMGVDLTMAQDCAGADLVHSHTWYANLGGHLASLLHGVPHVVSAHSLEPLRPWKAEQLGGGYALSSWVERTAYESAAAIIAVSHGMRADILRSYPQVEPDRVRVVHNGIDAEQWQPRADEAVLARHGIDPARPSVVFVGRITRQKGLPHLLRAARLLPPEVQLVLCAGAPDTPEIQAEVEGLIAELREVRDGVVWIAEMLPRHEVVAVLTSGTVFVCPSVYEPLGIVNLEAMACGLPVVGTATGGIPEVVADGTTGWLVPIEQVQDGTGTPVDPDGFVRDLAAALTDAVSDPERARQRGEAGRRRAVEEFSWGSIAERTLEVYGSVLR
>NZ_CP044548.2|WP_123091736.1|773707_774454_-|hypothetical-protein
MFELPGSVRVALWATVVIGSGGDLAGVAPRALPDVDHVAGLLDRLTLWRDLGEGAVLVALPSAGHVASLPRTDDEARDAAVEAGEALYVAGIGGVLVPEHSTYGSSGRRVDWHAFDAEPVPVHRVEALSHRQLERDLMELVTTARDDLERVGGQPFADSLAREIADNRLGGAWGLPDALDDRAYRVITLAGTVGAAARIGTEHSGAIDARTAADRDATLLALARGADRLLADATNAACAQLAGWVPAR
>NZ_CP044548.2|WP_123091737.1|774484_775270_+|ABC-transporter-ATP-binding-protein
MSDVLAFAGVGVRRGRTDLLDGVDWEVEEGQRWVVLGPNGAGKTTLLQLAAGRIHPTTGVAGVLGEVLGAVDVFELRPRIGLASSALASAIPPQELVRDVVVTASWGVTGRWREEYHELDHERAAELLDALGAAHLAQRTFGTLSEGERKRVQIARALMTDPELMLLDEPAAGLDLGGREDLVARLGAIAEDLASPALVMVTHHVEEIPPHFTDILLLREGQVVAQGPIEITLTAQNLTDTFGLPLELEQHGERWAARARR
>NZ_CP044548.2|WP_123091738.1|775309_775762_+|NfeD-family-protein
MEWLSDNLWLAWIALAMIFVAVEAATADFVFIMLAGGALAGALAAGSGVVFSLQVVLAVLVAMLLIGLVRPLVKRQFATSEASGSIGSAALQGRLARVIETVTETDGRVKLAGEVWSARVPDGAPACEPGEEVRVLQIDGATVVVTNQPA
>NZ_CP044548.2|WP_123091739.1|775823_777086_+|SPFH/Band-7/PHB-domain-protein
MESIPILVFLAALVAFALVILFKTVRIVPQQTALIIERLGRYSRTLEGGIHILVPFVDKVRANIDLREQVVSFPPQPVITSDNLVVNIDTVIYYTVIDAKSAVYEIANFIQGIEQLTVTTLRNVIGSLDLEQTLTSRDQINGQLRGALDEATGRWGIRVNRVELKAIDPPMSIQESMEKQMKAERDRRAAILNAEGTKQSAILTAEGEKQSQILRAEGSAQARILEAQGQARAIQQVFDAIHRGKPTQKLLAYQYLQVLPQIARGDSNKMWIIPSEVTDALKAMGGMLGGGAAPGSDGGLDDEPFVEVDGPEDNAFAETALEDPAEALKEARGQAGQASREASEHATPASRVQPSSGQGQGVRLPQPRPASEDATGAGAPAESDATAPASPPPPVAPEPPESEGPPAGPAGPPSPGRPPL
>NZ_CP044548.2|WP_123091740.1|777147_777918_+|sulfite-exporter-TauE/SafE-family-protein
MSWWEVLLVVLAGVWAGGINTVVGSGTLVTFPTLLAMGVPPVTANVSNSIGLVAGGITGTWGYLPELRGAKRLVLRLVPMSLLGAVIGALLLLWLPAEAFETIVPVLIGIGLLLVIFGPRMQRWAARQHHDGVEPRWQVVALMSGVLVAGVYGGYFGAAQGVILIGLLSSLSPEPLQRLNGVKNALGTVVNAVGSLVFVVVSPELVSWTIVLAVGCGALVGGLVGARVGRRLPPVVLRSVIVVIGVVGIVKMVFFP
>NZ_CP044548.2|WP_123091741.1|777931_778645_+|sulfite-exporter-TauE/SafE-family-protein
MTTTLLLGVVVLVGSFVQASLGFGIAVVAAPFVVLLEPELMPASLLVLGLVLPLLQLLSGPRDVDRRLLGWALGGRLALTPVGAWLVHVLPTRGIAVAVGLLVLVSTVLSIRTVETTARPSTALGAGAITGVSGTAASIGGPFLAIVLQHEDPVRIRSTLSAFFVVGSSASLLSLAVSGQVTREQMTTSAVWVPFVVAGMLLARPVQDRLPRTAMRHGVLALCVVSSVVVTGRALLT
>NZ_CP044548.2|WP_123091742.1|778654_779461_+|RNA-methyltransferase
MPETITDPADPRLRDYVGLTDVALRRVLEPEGGLYLAESEKVIRRALAAGHRPRSLLMSPRWLDDLADVVAACEEDGVPVYVGEPEVVEGITGFNLHRGALASMHRPDLPSVAEVCGDARRVLVLEDLVDHTNVGAVFRSAAALGVDAVLVTPRCADPLYRRSVRVSMGTVFQVPWTRLDQWPADVGVLQELGLVVAALALADDAVSLDDLAADPPDRLALVVGTEGDGLSRRTLAQADLTVTIPMRGGVDSLNAAAASAVAAWALRA

Crispr_ID: NZ_CP044548_4

• CRISPR_ID: NZ_CP044548_4
• CRISPR_location: 784629-784793
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP044548_4

Consensus_repeat	Method
CGGCGACGAGGAGTACGACGACGA	CRISPRCasFinder

spacers of NZ_CP044548_4

>4.1|784653|39|NZ_CP044548|CRISPRCasFinder
CCTCAACGAGGCCTACGGCGAGATGACCCCGCTCATCGT
>4.2|784716|15|NZ_CP044548|CRISPRCasFinder
CAGCGGCGACGAGGA
>4.3|784755|15|NZ_CP044548|CRISPRCasFinder
GGGCTACTCCGGTCT

CRISPR arrays and Neighbor proteins around NZ_CP044548_4

CRISPR arrays

The CRISPR arrays of NZ_CP044548_4

>merge|NZ_CP044548|4|784629-784793|CRISPRCasFinder
CGCCTTCGAGGCCTACGACGACGCCCTCAACGAGGCCTACGGCGAGATGACCCCGCTCATCGTCGTCGACGACGCCGACCTCGACGACAGCGGCGACGAGGAGTACGACGACGACGAGGACGACGAGGGCTACTCCGGTCTCGACGACGAGGAGTACGACGACGA

>NZ_CP044548|4|4|784629-784793|CRISPRCasFinder
CGCCTTCGAGGCCTACGACGACGC	CCTCAACGAGGCCTACGGCGAGATGACCCCGCTCATCGT
CGTCGACGACGCCGACCTCGACGA	CAGCGGCGACGAGGA
GTACGACGACGACGAGGACGACGA	GGGCTACTCCGGTCT
CGACGACGAGGAGTACGACGACGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123091746.1|781660_782797_-|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP044548.2|WP_123091747.1|782944_784267_+|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|181163
NZ_CP044548.2|WP_123091751.1|788008_789259_+|cysteine--1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside-ligase	unknown	unknown	gnl|CDD|183518
NZ_CP044548.2|WP_123091750.1|786634_787180_+|DUF3090-family-protein	unknown	unknown	gnl|CDD|378626
NZ_CP044548.2|WP_123091753.1|789943_790801_-|PAC2-family-protein	unknown	unknown	gnl|CDD|378251
NZ_CP044548.2|WP_123091739.1|775823_777086_+|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl|CDD|223407
NZ_CP044548.2|WP_123091741.1|777931_778645_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP044548.2|WP_123091745.1|780590_781301_-|aminotransferase-class-I-and-II	unknown	unknown	unknown
NZ_CP044548.2|WP_123091976.1|787149_787989_+|SCO1664-family-protein	unknown	unknown	gnl|CDD|274813
NZ_CP044548.2|WP_123091742.1|778654_779461_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP044548.2|WP_123091754.1|791601_792699_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP044548.2|WP_123091743.1|779602_780163_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|182339
NZ_CP044548.2|WP_068275869.1|784842_785886_-|magnesium-and-cobalt-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
NZ_CP044548.2|WP_123091744.1|780213_780594_-|DUF3037-domain-containing-protein	unknown	unknown	gnl|CDD|378608
NZ_CP044548.2|WP_123091755.1|792847_793711_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP044548.2|WP_123091977.1|790923_791562_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP044548.2|WP_123091748.1|784250_784463_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123091752.1|789401_789926_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123091749.1|785917_786625_+|MSMEG_4193-family-putative-phosphomutase	unknown	unknown	gnl|CDD|163560
NZ_CP044548.2|WP_123091740.1|777147_777918_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123091746.1|781660_782797_-|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.08681e-59
NZ_CP044548.2|WP_123091747.1|782944_784267_+|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|181163	PRK07906, PRK07906, hypothetical protein; Provisional.	0
NZ_CP044548.2|WP_123091751.1|788008_789259_+|cysteine--1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside-ligase	gnl|CDD|183518	PRK12418, PRK12418, cysteinyl-tRNA synthetase; Provisional.	0
NZ_CP044548.2|WP_123091750.1|786634_787180_+|DUF3090-family-protein	gnl|CDD|378626	pfam11290, DUF3090, Protein of unknown function (DUF3090). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.12792e-68
NZ_CP044548.2|WP_123091753.1|789943_790801_-|PAC2-family-protein	gnl|CDD|378251	pfam09754, PAC2, PAC2 family. This PAC2 (Proteasome assembly chaperone) family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 247 and 307 amino acids in length. These proteins function as a chaperone for the 26S proteasome. The 26S proteasome mediates ubiquitin-dependent proteolysis in eukaryotic cells. A number of studies including very recent ones have revealed that assembly of its 20S catalytic core particle is an ordered process that involves several conserved proteasome assembly chaperones (PACs). Two heterodimeric chaperones, PAC1-PAC2 and PAC3-PAC4, promote the assembly of rings composed of seven alpha subunits.	2.14248e-45
NZ_CP044548.2|WP_123091741.1|777931_778645_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.28619e-08
NZ_CP044548.2|WP_123091742.1|778654_779461_+|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.31899e-57
NZ_CP044548.2|WP_123091976.1|787149_787989_+|SCO1664-family-protein	gnl|CDD|274813	TIGR03843, Phosphatidylinositol_3-_and_4-kinase, conserved hypothetical protein. This model represents a protein family largely restricted to the Actinobacteria (high-GC Gram-positives), although it is also found in the Chloroflexi. Distant similarity to the phosphatidylinositol 3- and 4-kinase is suggested by the matching of some members to pfam00454.	5.97412e-96
NZ_CP044548.2|WP_123091754.1|791601_792699_+|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.35701e-17
NZ_CP044548.2|WP_123091743.1|779602_780163_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.34568e-53
NZ_CP044548.2|WP_068275869.1|784842_785886_-|magnesium-and-cobalt-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	4.60176e-145
NZ_CP044548.2|WP_123091744.1|780213_780594_-|DUF3037-domain-containing-protein	gnl|CDD|378608	pfam11236, DUF3037, Protein of unknown function (DUF3037). This bacterial family of proteins has no known function.	1.55505e-49
NZ_CP044548.2|WP_123091755.1|792847_793711_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.41111e-20
NZ_CP044548.2|WP_123091977.1|790923_791562_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	1.2648e-37
NZ_CP044548.2|WP_123091740.1|777147_777918_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.19666e-22
NZ_CP044548.2|WP_123091749.1|785917_786625_+|MSMEG_4193-family-putative-phosphomutase	gnl|CDD|163560	TIGR03848, MSMEG_4193, probable phosphomutase, MSMEG_4193 family. A three-gene system broadly conserved among the Actinobacteria includes MSMEG_4193 and homologs, a subgroup among the larger phosphoglycerate mutase family protein (pfam00300). Another member of the trio is a probable kinase, related to phosphatidylinositol kinases; that context supports the hypothesis that this protein acts as a phosphomutase.	4.11543e-93
NZ_CP044548.2|WP_123091739.1|775823_777086_+|SPFH/Band-7/PHB-domain-protein	gnl|CDD|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	1.13886e-70

Protein sequences

>NZ_CP044548.2|WP_123091748.1|784250_784463_-|hypothetical-protein
MVEYEFQVLSFPRETTRGQIRAALAEHAEYGRWELHRTVRYVGGQQRSWLRRKIIRVPRRDDPLGLSRSR
>NZ_CP044548.2|WP_123091747.1|782944_784267_+|M20/M25/M40-family-metallo-hydrolase
MEISAPQDEVVRLCQDLIRIDTTNYGPDGEGPGEREAADYVVEQLREVGYEPQRFESQPGRASVVLRIPGADRERGALCIHGHLDVVPANAQDWSVDPFEGVIKDGCVWGRGAVDMKDMDAMILACVRHLARTGTVPPRDLVVVFFADEEAGGVHGSQWLVQHHPELFEGVTEAISEVGGYSVTVPTPEGGDRRAYLLQTAEKGIVWLRLRASGRAGHGSVPNDDNAVLHLAQALSRIAEHKWPREYIASVRGLLDGLSEITGTGYSDEDLEELVEHLGGAAGFVRGSLQDTANPTMLTAGYKHNVIPQEAVAAVDCRFLPGHEESLMATIAELAGDRVVVEVEHRDIALDSPFEGPLVDAMKAALLAEDPEAAILPYCLSGGTDNKALSTMGITGYGFAPLRLPADLDFAPMFHGIDERVPTESLEFGAKVLLRLIETC
>NZ_CP044548.2|WP_123091746.1|781660_782797_-|serine-hydrolase
MTIHGHTDPRLTGLRDALAAMVDSGEELGAAISVDLDGETLVDIWGGHADVARTRPWERDTIVNVWSTTKEVTALAVLLLVERGLVDLDAPVATYWPEFAANGKEGVLVRHVMSHTSGVSGWDQPFVLTDMYDRETATARLAAQAPWWEPGTASGYHAQNQGHLLGEIIRRTSGRTLTQLVAEEIAGPLGVDLQIGATERDDDRVAEIVPPPPLPMGLSQVPADSPMVRTFTGPVASAAAANTIPWRRAELGALNAHTNARALARTFSVISRGGAVDDVRLLSPGTIEQIFREQSRGVDLVLGVPLRFGIGFALPEPQTVPYIPDGRVCFWGGWGGSMTVMFPERSLTVSYVMNKMAPGIIGSDRAARYLTEVLDAVG
>NZ_CP044548.2|WP_123091745.1|780590_781301_-|aminotransferase-class-I-and-II
MPGLVEADDLGMYVVKMRGAGQGLPVLVAEVLVGEMGRALGVAVPELVEVDLSGEIARFEADEEVQDLLTASVGLNLGMDYLPGAFGYDGSQPADPEVAALVLWLDACTSNVDRTWANPNLLRWGGQVWAIDHGAALWFHHAWARKAPSADRFAAQPFDASTHVLRDLAGDLGEVHERARSVLTHERLVEIVDLVPDEWLTPGEHLPTTQAIRDEYVRHLVQRLASPDAWLPGASR
>NZ_CP044548.2|WP_123091744.1|780213_780594_-|DUF3037-domain-containing-protein
MTLQTYQYVVLRCVPRAEREEFVNVGVVLRSQGHDYLRAAFALDEERLHALWPDLDVAAVHAALEVVCDVALGRTGGGRPDLDGDGRRFGWISAPRSTVVRPGPVHGGLTQDPAAELERLLDELVR
>NZ_CP044548.2|WP_123091743.1|779602_780163_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MDLDSRPTAPEPYDLLPQVPSFEVRSDTFADGQALPEAQVFDDWGFEGGNRSPHLAWSGAPEGTKSYAVSCFDPDAPTPAGFWHWTVLGIPADVTELAEDAGAEGGSGLPDGAFMTATDYGTKAFGGAAPPAGDRPHRYVFAVHALDVEPDALPVDDSVTCTVAAFNYLGATIARAVVTGTYQTPA
>NZ_CP044548.2|WP_123091742.1|778654_779461_+|RNA-methyltransferase
MPETITDPADPRLRDYVGLTDVALRRVLEPEGGLYLAESEKVIRRALAAGHRPRSLLMSPRWLDDLADVVAACEEDGVPVYVGEPEVVEGITGFNLHRGALASMHRPDLPSVAEVCGDARRVLVLEDLVDHTNVGAVFRSAAALGVDAVLVTPRCADPLYRRSVRVSMGTVFQVPWTRLDQWPADVGVLQELGLVVAALALADDAVSLDDLAADPPDRLALVVGTEGDGLSRRTLAQADLTVTIPMRGGVDSLNAAAASAVAAWALRA
>NZ_CP044548.2|WP_123091741.1|777931_778645_+|sulfite-exporter-TauE/SafE-family-protein
MTTTLLLGVVVLVGSFVQASLGFGIAVVAAPFVVLLEPELMPASLLVLGLVLPLLQLLSGPRDVDRRLLGWALGGRLALTPVGAWLVHVLPTRGIAVAVGLLVLVSTVLSIRTVETTARPSTALGAGAITGVSGTAASIGGPFLAIVLQHEDPVRIRSTLSAFFVVGSSASLLSLAVSGQVTREQMTTSAVWVPFVVAGMLLARPVQDRLPRTAMRHGVLALCVVSSVVVTGRALLT
>NZ_CP044548.2|WP_123091740.1|777147_777918_+|sulfite-exporter-TauE/SafE-family-protein
MSWWEVLLVVLAGVWAGGINTVVGSGTLVTFPTLLAMGVPPVTANVSNSIGLVAGGITGTWGYLPELRGAKRLVLRLVPMSLLGAVIGALLLLWLPAEAFETIVPVLIGIGLLLVIFGPRMQRWAARQHHDGVEPRWQVVALMSGVLVAGVYGGYFGAAQGVILIGLLSSLSPEPLQRLNGVKNALGTVVNAVGSLVFVVVSPELVSWTIVLAVGCGALVGGLVGARVGRRLPPVVLRSVIVVIGVVGIVKMVFFP
>NZ_CP044548.2|WP_123091739.1|775823_777086_+|SPFH/Band-7/PHB-domain-protein
MESIPILVFLAALVAFALVILFKTVRIVPQQTALIIERLGRYSRTLEGGIHILVPFVDKVRANIDLREQVVSFPPQPVITSDNLVVNIDTVIYYTVIDAKSAVYEIANFIQGIEQLTVTTLRNVIGSLDLEQTLTSRDQINGQLRGALDEATGRWGIRVNRVELKAIDPPMSIQESMEKQMKAERDRRAAILNAEGTKQSAILTAEGEKQSQILRAEGSAQARILEAQGQARAIQQVFDAIHRGKPTQKLLAYQYLQVLPQIARGDSNKMWIIPSEVTDALKAMGGMLGGGAAPGSDGGLDDEPFVEVDGPEDNAFAETALEDPAEALKEARGQAGQASREASEHATPASRVQPSSGQGQGVRLPQPRPASEDATGAGAPAESDATAPASPPPPVAPEPPESEGPPAGPAGPPSPGRPPL
>NZ_CP044548.2|WP_068275869.1|784842_785886_-|magnesium-and-cobalt-transport-protein-CorA
MIVDQARYRDGVRLPCEDISTEIARLRAEAPGRPEGSADFVWIGLKDPSPQTFQRVVGDELELHHLAIEDAVAGDQRAKVERYGDTWFAVLKPLRYLDETSDVETGELMVFVGPDFVLTVRRGEASPLADLRHRLEEDPAPLRHGPWGVFHAVLDTVVDEYLAIEDELQVDLEGIETAVFEPSSGLTSEEIYTLKREVLEFKRAALPLARPMGFLTSPSSPVAHGELRLLFRDVSDHLTQALESLESMDRLLTDVLSAHLAQVGVEQNRVSMKQNEDMRRISAWVAIAALPTMIAGVYGMNFERMPELTASVRVSGHEVYYGYYVVLAVMVAACLVLYRLFKRSGWL
>NZ_CP044548.2|WP_123091749.1|785917_786625_+|MSMEG_4193-family-putative-phosphomutase
MAYCLLLRHARSSANAAGLLAGWSAGVSLDDTGRAQAQEVVDRLGELPLVRVVTSPLDRCLETVEPLRARLGLDLDVEPDIGEAHYGGWTGRPLVELAKEPLWRTVQSTPSQAVFPPSDEHAHESIATMAQRAVAAIRRVDAQVEAEHGAHAMWLAVSHGDIIKSVVADASATPLDDFQRFVVDPASVSVLRYTPERPFVLRVNDSGPLRPVPQPSTTTPETTPPGDAVVGGGAG
>NZ_CP044548.2|WP_123091750.1|786634_787180_+|DUF3090-family-protein
MSVFEYDPPERFVVGTVGPPGDRTFYLQASDGHRRHQIAVEKVHVGVLAERIETLLDEVGGLEGGVAAAVGSADNAPLDTPITEDFRVLALSLAWDEERRVVVIECHDHDPDELAEEGDPQGEPLVGGPSTLRVVLSPAKARAFARRCETVVSAGRPSCPFCGGPLDPEGHICPRANGYRR
>NZ_CP044548.2|WP_123091976.1|787149_787989_+|SCO1664-family-protein
MPPRERLPALTERLAPQPCEIETHLAEGELTMLGAHPEASNLAIVCEVEHEGGTLTAIYKPVQGERPLWDYPDGHLAHRERAAYLVARLGGFDCVPTTVLRAGPLGEGSVQRWVGTLDEPADSPVAVTRPGQIPPGYLRVLSGEDERGTGVVLSHPDDPVLRSLSVLDAVINNSDRKGSHVLLEGDGVYGIDNGVSLSVEPKLRTVLWGWAGDPLTDADRARVERLVEAIEGSPEAGELDELLTVTEVDALVARCERLLRAGRHPRPGHGWPSVPWPPV
>NZ_CP044548.2|WP_123091751.1|788008_789259_+|cysteine--1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside-ligase
MKSWSAPAVPTLPGSGPTPRLHDTLTDAVAEVRPEQGRLSLYVCGVTPYDTTHMGHAATYVTFDVLHRAALDSGLGVDYVQNVTDVDDPLLERAERDGVDWRDLATSQIELFSQDMAALRVIPPKAYVGVVEAMPRIVAVVERLVDAGVTYTLTEDATGAQDTYLDVTAVGGVEQVSPLPEATMLEYSAERGGDPDRAGKRHRLDPMLWRGERDGEPAWESTLLGRGRPGWHIECTAIALDHLGETVGVQGGGSDLEFPHHPMTALQAVAATRRSPFATHTTHQAMVGLDGEKMSKSKGNLVRVSDLRREGVDPAAIRLVLLAHHYRTEWSWTEDSLRHAQRRLDRWRRATSLPSGPGVGTLADEVRTALADDLDTAAALDAVDRWCEQAEAGEGADEDAPALVVDVVDALLGVEL
>NZ_CP044548.2|WP_123091752.1|789401_789926_-|hypothetical-protein
MILPEVRDPRLVTVRRGGTLTDADHRLLALWAALCAEHVLGLVEEEVPGDPRPRAAVEAVRSWAGGELPMMRARAVGGHAMGAARPLTGPARLAAYAAGQAACVPHVAEHDLGAAAYAIRAVHHAHPEDPSAGVGERDWQREQLPAAVRDLVLEDQARRDAICWGAFGDAGPRR
>NZ_CP044548.2|WP_123091753.1|789943_790801_-|PAC2-family-protein
MIELQDIPELHDPVMILAFEGWNDAGEAATSTLLHLAEAWDADPVAALDPEDYYDFQVTRPVVMGRPGQRRVDWRTTRVLLASPDELDRDVVLVLGIEPSFRWRTFCEEIVDLASDLGVRTVVSIGALLADVPHTRPIPVSATSDDERTIHRYDLEASTYEGPTGIIGVVADAARREDMASISLWAGIPHYAGHVPSPKATYAVLRALERLLDVSLPHGTLEEEARAWERGVDEAAEADEDIREYVEQLEQAQDTAQLPEASGDAIAKEFERYLRRRRDDPPAAG
>NZ_CP044548.2|WP_123091977.1|790923_791562_+|HAD-family-phosphatase
MDGTLVDTEPYWIRAEHELVERFGGRWSDELAHELVGNPLLVSADFIIERSPVTLTPHEVVDELMSSVIAQVHDHVPWRPGAQELLAEAVAAGVPNALVTMSWRPLVTAVLDTLEPGCFAAVVTGDEVTHGKPHPEPYERAAALLGVDPADAVAVEDSPTGVRSATAAGVPTIAVPHVVPVPPVEGSVQLETLEGVSLADLVTRARSPFASA
>NZ_CP044548.2|WP_123091754.1|791601_792699_+|alpha/beta-fold-hydrolase
MAANAPAPRQQIRFCRSVDGTQIAYAVHGSGPPLVVDSCWLSHLQHDWSSPVWRHHLLEWGREHTVVRFDERGHGLSDRDVTDHGLEVRVADLEAVVDDAGLERFDLLAMAQGGPVAICYTARHPQRVSRLVFYGSYSGQQSKDPTEAAMDDTLDALIAVGWARPDSTFRRVFTSLMIPGASEEQRVWLDELQRTSTSAETARESRRQRLVADASHLLAQLDVPTLVIHSRGDRMNDFSEARYLAAHVADARLVALESENHIVLEDDDAWPVYRAELSRFLAEPVPVRGGTAPGGGRSEGLEDLSPREREILALAAQGRDNDEIARSLVLSTRTVERHLSNVYAKLDLHGKSARTAAVARLLTGR
>NZ_CP044548.2|WP_123091755.1|792847_793711_+|class-I-SAM-dependent-methyltransferase
MSTIAPDGPAPVDPPAEDADTALKARHRAMWALGDYPAVAREVVAPLGPVLVEAAGVHAGQRVHDVAAGPGTVAIPAARTGAEVVATDLTPELLEAGRAAAEAEGLDIRWVVADAEHLPCDTGEFDVALSCVGVMFAPHHQAVADQLARVVRPGGTIGLLSWTPEGFIGQMFAKMRPYAPPPPAGSQPPPLWGHLDHVRDLLGDRAEITTAVQQDLVVDRFAGPQDFLDLFKSSYGPTIAVYRALGEGSERAAALDAELIGLVERFDVGDGTTVLPWEYLLVTATCR

Crispr_ID: NZ_CP044548_5

• CRISPR_ID: NZ_CP044548_5
• CRISPR_location: 810924-811009
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP044548_5

Consensus_repeat	Method
CAGCTTTCCCGCCCTGGGCGGGAA	CRISPRCasFinder

spacers of NZ_CP044548_5

>5.1|810948|38|NZ_CP044548|CRISPRCasFinder
CATTCGACCTCGGGCGAGAACATTTCCTTCCCGATGTC

CRISPR arrays and Neighbor proteins around NZ_CP044548_5

CRISPR arrays

The CRISPR arrays of NZ_CP044548_5

>merge|NZ_CP044548|5|810924-811009|CRISPRCasFinder
CAGCTTTCCCGCCCTGGGCGGGAACATTCGACCTCGGGCGAGAACATTTCCTTCCCGATGTCGCACTTTCCCGCCCTGGGCGGGAA

>NZ_CP044548|5|5|810924-811009|CRISPRCasFinder
CAGCTTTCCCGCCCTGGGCGGGAA	CATTCGACCTCGGGCGAGAACATTTCCTTCCCGATGTC
GCACTTTCCCGCCCTGGGCGGGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123091774.1|819131_820073_-|5'-3'-exonuclease	unknown	unknown	gnl|CDD|214682
NZ_CP044548.2|WP_123091761.1|802463_803033_-|DUF3054-domain-containing-protein	unknown	unknown	gnl|CDD|378616
NZ_CP044548.2|WP_123091772.1|815420_816317_+|diacylglycerol-kinase	unknown	unknown	gnl|CDD|237021
NZ_CP044548.2|WP_123091764.1|806158_807649_+|proteasome-accessory-factor-PafA2	unknown	unknown	gnl|CDD|376995
NZ_CP044548.2|WP_068275787.1|820127_820553_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|214628
NZ_CP044548.2|WP_123091762.1|803025_804009_-|ribose-phosphate-diphosphokinase	unknown	unknown	gnl|CDD|234929
NZ_CP044548.2|WP_123091768.1|811032_812142_-|DUF3866-family-protein	unknown	unknown	gnl|CDD|379008
NZ_CP044548.2|WP_123091773.1|816343_819079_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|226947
NZ_CP044548.2|WP_123091766.1|807928_809323_+|Pup--protein-ligase	unknown	unknown	gnl|CDD|274725
NZ_CP044548.2|WP_123091771.1|814624_815404_+|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl|CDD|376413
NZ_CP044548.2|WP_123091775.1|820604_822197_+|apolipoprotein-N-acyltransferase	unknown	unknown	gnl|CDD|143595
NZ_CP044548.2|WP_123091765.1|807685_807886_+|ubiquitin-like-protein-Pup	unknown	unknown	gnl|CDD|368536
NZ_CP044548.2|WP_123091763.1|804005_805118_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|369561
NZ_CP044548.2|WP_123091769.1|813219_814182_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP044548.2|WP_123091978.1|812269_813223_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|379100
NZ_CP044548.2|WP_083968853.1|805114_806122_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|369561
NZ_CP044548.2|WP_123091760.1|800625_802296_+|proteasome-ATPase	unknown	unknown	gnl|CDD|200312
NZ_CP044548.2|WP_123091770.1|814245_814548_+|twin-arginine-translocase-TatA/TatE-family-subunit	unknown	unknown	gnl|CDD|234797
NZ_CP044548.2|WP_163562370.1|809426_810386_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl|CDD|365980
NZ_CP044548.2|WP_068275809.1|810449_810836_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223619

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP044548.2|WP_123091769.1|813219_814182_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	1.2e-46	154.3	0.0
NZ_CP044548.2|WP_123091978.1|812269_813223_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	4.1e-42	139.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123091774.1|819131_820073_-|5'-3'-exonuclease	gnl|CDD|214682	smart00475, 53EXOc, 5'-3' exonuclease.	1.25142e-72
NZ_CP044548.2|WP_123091761.1|802463_803033_-|DUF3054-domain-containing-protein	gnl|CDD|378616	pfam11255, DUF3054, Protein of unknown function (DUF3054). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.43973e-26
NZ_CP044548.2|WP_123091772.1|815420_816317_+|diacylglycerol-kinase	gnl|CDD|237021	PRK11914, PRK11914, diacylglycerol kinase; Reviewed.	9.83574e-91
NZ_CP044548.2|WP_123091764.1|806158_807649_+|proteasome-accessory-factor-PafA2	gnl|CDD|376995	pfam03136, Pup_ligase, Pup-ligase protein. Pupylation is a novel protein modification system found in some bacteria. This family of proteins are the enzyme that can conjugate proteins of the Pup family to lysine residues in target proteins marking them for degradation. The archetypal protein in this family is PafA (proteasome accessory factor) from Mycobacterium tuberculosis. It has been suggested that these proteins are related to gamma-glutamyl-cysteine synthetases.	0
NZ_CP044548.2|WP_068275787.1|820127_820553_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	8.07937e-35
NZ_CP044548.2|WP_123091762.1|803025_804009_-|ribose-phosphate-diphosphokinase	gnl|CDD|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	1.21482e-124
NZ_CP044548.2|WP_123091768.1|811032_812142_-|DUF3866-family-protein	gnl|CDD|379008	pfam12982, DUF3866, Protein of unknown function (DUF3866). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 352 and 374 amino acids in length.	4.06345e-137
NZ_CP044548.2|WP_123091773.1|816343_819079_+|DEAD/DEAH-box-helicase	gnl|CDD|226947	COG4581, COG4581, Superfamily II RNA helicase [DNA replication, recombination, and repair].	0
NZ_CP044548.2|WP_123091766.1|807928_809323_+|Pup--protein-ligase	gnl|CDD|274725	TIGR03686, pupylate_PafA, Pup--protein ligase. Members of this family are the Pup--protein ligase PafA (proteasome accessory factor A), a protein shown to regulate steady-state levels of certain proteasome targets in Mycobacterium tuberculosis. Iyer, et al (2008) first suggested that PafA is the ligase for Pup, a ubiquitin analog attached to an epsilon-amino group of a Lys side-chain to direct the target to the proteasome. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP044548.2|WP_123091771.1|814624_815404_+|twin-arginine-translocase-subunit-TatC	gnl|CDD|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	9.48505e-64
NZ_CP044548.2|WP_123091775.1|820604_822197_+|apolipoprotein-N-acyltransferase	gnl|CDD|143595	cd07571, ALP_N-acyl_transferase, Apolipoprotein N-acyl transferase (class 9 nitrilases). ALP N-acyl transferase (Lnt), is an essential membrane-bound enzyme in gram-negative bacteria, which catalyzes the N-acylation of apolipoproteins, the final step in lipoprotein maturation. This is a reverse amidase (i.e. condensation) reaction. This subgroup belongs to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 9.	4.16702e-84
NZ_CP044548.2|WP_123091765.1|807685_807886_+|ubiquitin-like-protein-Pup	gnl|CDD|368536	pfam05639, Pup, Pup-like protein. This family consists of several short bacterial proteins formely known as (DUF797). It was recently shown that Mycobacterium tuberculosis contains a small protein, Pup (Rv2111c), that is covalently conjugated to the e-NH2 groups of lysines on several target proteins (pupylation) such as the malonyl CoA acyl carrier protein (FabD). Pupylation of FabD was shown to result in its recruitment to the mycobacterial proteasome and subsequent degradation analogous to eukaryotic ubiquitin-conjugated proteins. Searches recovered Pup orthologs in all major actinobacteria lineages including the basal bifidobacteria and also sporadically in certain other bacterial lineages. The Pup proteins were all between 50-90 residues in length and a multiple alignment shows that they all contain a conserved motif with a G [EQ] signature at the C-terminus. Thus, all of them are suitable for conjugation via the terminal glutamate or the deamidated glutamine (as shown in the case of the Mycobacterium Pup). The conserved globular core of Pup is predicted to form a bihelical unit with the extreme C-terminal 6-7 residues forming a tail in the extended conformation. Thus, Pup is structurally unrelated to the ubiquitin fold and has convergently evolved the function of protein modifier.	5.98072e-14
NZ_CP044548.2|WP_123091763.1|804005_805118_-|alpha/beta-hydrolase	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	9.9002e-78
NZ_CP044548.2|WP_123091769.1|813219_814182_+|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.08761e-36
NZ_CP044548.2|WP_123091978.1|812269_813223_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.16134e-33
NZ_CP044548.2|WP_083968853.1|805114_806122_-|alpha/beta-hydrolase	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	5.37274e-76
NZ_CP044548.2|WP_123091760.1|800625_802296_+|proteasome-ATPase	gnl|CDD|200312	TIGR03689, pup_AAA, proteasome ATPase. In the Actinobacteria, as shown for Mycobacterium tuberculosis, some proteins are modified by ligation between an epsilon-amino group of a lysine side chain and the C-terminal carboxylate of the ubiquitin-like protein Pup. This modification leads to protein degradation by the archaeal-like proteasome found in the Actinobacteria. Members of this protein family belong to the AAA family of ATPases and tend to be clustered with the genes for Pup, the Pup ligase PafA, and structural components of the proteasome. This protein forms hexameric rings with ATPase activity. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP044548.2|WP_123091770.1|814245_814548_+|twin-arginine-translocase-TatA/TatE-family-subunit	gnl|CDD|234797	PRK00575, tatA, Sec-independent protein translocase subunit TatA.	2.04842e-24
NZ_CP044548.2|WP_163562370.1|809426_810386_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl|CDD|365980	pfam00254, FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase.	5.13002e-24
NZ_CP044548.2|WP_068275809.1|810449_810836_+|peptidylprolyl-isomerase	gnl|CDD|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	1.2359e-37

Protein sequences

>NZ_CP044548.2|WP_068275809.1|810449_810836_+|peptidylprolyl-isomerase
MPFDPSTTKPEIEFPGDTPPSELVLEDITVGDGREATPGDPIKAHYVGVAHSTGEEFDASWNRGAPLAFTVGVGQVIQGWDQGLLGMKEGGRRKITIPPHLGYGDRGAGGAIKGGETLIFVVDLVSVG
>NZ_CP044548.2|WP_163562370.1|809426_810386_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MISRARATVALTAAAALTLTACGGDDTEAPEAASSGAVDQVKVTAGTEKAAPKIALEDKSVSTSKTEVKTVKEGKGAPVSKDDVVTVDIALYNGTSGKPIPNTETYTADPIAIDLGNEQIFPGLRNGIVGQKVGSTATAVVPPKEMFGETGNEQLGVAATDSVVMVYDVKDVMLKEAEGKEVAAKSGLPKVTYSTDKAATFEMPKGKAPSSTTAQTLVQGDGATVKKGDTAYVSYTGALWKNGKVFDSSKQEGRRPFAVPVGGGQVIKAWDEELAGTKVGDRVLLVVPPKDGYGKTGSPDGSITKDDTIVFVIDVLGKV
>NZ_CP044548.2|WP_123091766.1|807928_809323_+|Pup--protein-ligase
MERRIYGIETEFGVTCTSQGRRRLTPDEVARYMFRSVVRWGRSSNVFLGNGARLYLDVGSHPEYATAECDDLLDLVAHDRAGELVVQQLVDDAQTRLAEDEVDGEIYVFKNNVDSAGNSYGCHENFLVARTDDFGAITEGLLPFLISRQLVAGTGKVMSTSQGPVFSVSQRADHIWEGVSSATTRSRPIINTRDEPHADAERYRRMHVIVGDSTMTETTTLLKVGSASLVLRMLESGVRMDHLRLENPIRAIRDISLDITGRATVRLADGRQMSGLELQQAYLDGVLELVEREGIDDAVTTQVVELWQRTLTAIETDRLDLVATEVDWVVKHRLLDAYAASRGVGMEDPRIAQLDLAYHDIDPQRGVHHVLQRAGRVARVVDDARVAAAVDTPPQTTRARLRGDFVRAAREHGRDFTVDWVHLKLNDATQRTILCKDPFAAVDERVDALIASMRPASPEPAAAP
>NZ_CP044548.2|WP_123091765.1|807685_807886_+|ubiquitin-like-protein-Pup
MAGQEQVRRSGGGGEDETPGDDAFGQVSASNAARDEGLDSVLSDIDGVLETNAEEFVKSFVQKGGE
>NZ_CP044548.2|WP_123091764.1|806158_807649_+|proteasome-accessory-factor-PafA2
MSVRRVMGIETEYGISVPGQPWADPVQTSGLVISRYAREHGLRATHGAWDYSDEQPLHDARGFSMPRDEADPTQLTDEEQPGLANVVLTNGARLYVDHAHPEYSSPEVMTPRDAVVHDRAGELVMREAVELLSTRPPGVTLYKNNTDGKGASYGTHENYLLDRATPFARVVRDLTPFFVARQVVIGAGRVGLGRESEGAGYQICSRADFFEAEVGLETTFRRPIINTRDEPHADPDRYRRLHVIVGDANLADVANLLKMGSTSLVLALVEADAVRGRLALRDPLRALREVSHDPTCTALVELADGRRMTAVQLLWAYRELIGEHLERHGSDEATDEVLAHLDRVLTLLESDPMSAAKDLDWVAKLSILQGYRDRDGLAWGDLRLQAVDIQYSDIRPAKGVFARLEAAGRITRLTTPEEVEAAVTTPPADTRAWLRGRLVRDHAPDVISASWDSVVLRVPRGVARISMPEPTALGRDATAAALAHDTVTEVVEALGA
>NZ_CP044548.2|WP_083968853.1|805114_806122_-|alpha/beta-hydrolase
MPSATPSAWMPLRTRALAALLRATSGPVDTISPARLARTRRRVPLHRPLTWAIGTPTKGVTTTVREVPVRDGARVRVRVHRPDYVEGALPVVMHFHGGGFAMGHPTAFDPVCTRVAQVAGAVVVSVGYRMAPEHRAPTAVHDCADVTRWVLAHAAELGADPDRLALTGDSAGGNLAAAVAQGLVADGVSALRHLALTYPAPDLTEREVDLVLEQEDVEVPPHGFPVITPDMLRAFRSLYLGDLDGSDPIVSPARGELAGLPPTLVQTAELDPLRLDGEAFAQALRDAGVPVRHTRYRGSPHGFLSLPGLTAAGHPALEELAAEMAHHLRPTKEPA
>NZ_CP044548.2|WP_123091763.1|804005_805118_-|alpha/beta-hydrolase
MTARPHLARPRPARAPRPALRTRVVTDLLERLGRRPVEDSDLDDIRAKRETVYPTRAPFTWITGPVGRGVRVETVSAPVRDGARIPLRCYLPAMPGPLPLLVFFHGGGWVQGSTAMYDPLCSRLAEQVGAVVVSVDYRMAPEHLFPTAAHDAVDVVSWLVEHGASLPVLADADLTRVGLAGDSAGGNLGAVVAQQLRDLRGPDGEPVLRHQALIYPATDLTMSSPSIDEHADGPVLTRAGITAFRALYLDGTLGVREDHRADPRHRDPLASPLAGDATGVAPALVQAGELDPLRDDATRYAEHLAEAGVPVRCTTYRRLPHGFASMPGACPGADAAHAELVGEIAHHLHASVGSQRPLAVGDAEDQEHAQ
>NZ_CP044548.2|WP_123091762.1|803025_804009_-|ribose-phosphate-diphosphokinase
MREIVVFSGSAHRELAERICDQLGVPLSPSRTTRFSNDCLQTQLLANCRQRDVYVVQPLVAPTQDHLMELLLMLDAARGASAARVTAVVPHYAYARSDKKDASRISIGGRLVADMITAAGADRVITMALHAPQVHGFFSVPVDHLTALGVLAEHFRGRDLDDAVVVSPDLGNAKEATQFARLLGLPVAAGSKQRTSDDTVVVESVVGDVRGRHAIVLDDEIATGGSIVELLAKLEELGCTGASVACTHGLFAGRAVERLREHPMVDEVVTTDTVPAPDGWPQLQVRSVSGLFAQAISRIHAGESVSSLFDGVDPTHAPPQPSLFDRA
>NZ_CP044548.2|WP_123091761.1|802463_803033_-|DUF3054-domain-containing-protein
MPERDTARSAAAALALDVLVVAVFVVVGRRSHAEGVTLAGWLETAWPFLAGLVLGWVGVVAGLGRAPVTLATGLPVWVATVFGGMALRDMSGQGTALPFVVVATLSLALGLLGWRAAATLLGRRRAAAPSSPTSHRGVAVGEPTPDPLGQRELGEQDITTPGRGVVPPQERARYGRRPDAEADRPDADD
>NZ_CP044548.2|WP_123091760.1|800625_802296_+|proteasome-ATPase
MSTGATGAVPQGPSPAEQLRTTQRELSTKTSQLSTLSSQNERLVRTLKDAREQIVTLRAEIDRLAQPPSAYAQLVGVHDDGTVDVLSNGRKMHVAVSPTIEADALEVGREVLLNEAMNVVSVHDPDVAGDVVLVKELLDDGRLLVLARQDEERVVRQGAALRRERVRVGDAVLLEARSNIALELIPKAEVADLVLEEVPDLSYEDIGGLSGQIETIRDSVELPYLHAELYERHQLKPPKGVLLYGPPGCGKTMIAKAVASSLARKVAERDGRDAATATNAYFLNIKGPELLNKYVGETERHIRLIFHRAREKSSDGTPVVVFFDEMDSLFRTRGSGVSSDVETTIVPQLLAEIDGVEGLENVIVIGATNREDMIDPAILRPGRLDVKIKIERPDAQAAREIFAKYLTADLPLHPHDLGDHDGSHERTVVAMIDAVVERMYAQIPENQFLEVTYAGGDKEVLYFKDFSSGAMIQNVVDRAKKLAIKEFLTSGVEGLREEHLLASCLAELRENEDLPNTTNPDDWARVSGKKGERIVYIRTLVGTASGTSAGKSIDLG
>NZ_CP044548.2|WP_123091768.1|811032_812142_-|DUF3866-family-protein
MIHWRRGTVSSVTDGWGPVVTVDVELDGGGVMAALADTPIVGTPQVGDTVLLNASALLKGLGTGGQALVVAIPDALPPDPVAADGARPPGHIVKARYAPLQTMVLALEEQESPHHEAMADHPQVVAGDLEGMPVVAAELHSALPAVVAGIHADRPGARVAYVMTDTGSLPLGHSRLVAAMRETGMLTSTTSVGQAYGGEHETITLHSALLAARYVLGADVVVVAQGPGNAGSATPWGYSGISQGEVLNTVHTLHGRGVAVLRVSAADPRGRHRGLSHHTATTLGRVVLGSADVPLADDDDLSPGLRDAVEAVCASATGRLSPVLVPAAGLDEALRACPVPLTTMGRGYASERAAFVTAAAAGRHAAALL
>NZ_CP044548.2|WP_123091978.1|812269_813223_+|WYL-domain-containing-protein
MNLTMCLLSTRRALPKARIRTMVEAYQGVESDEAFDRMFERDKDELRGLGIPLVTEQIGGAFEDEPGYRIDQRDYALPDLSFAPDELAVIGLASRVWTHAAMAPSAATAWRKVASLEPGDGATEDPFVGIEPTLGGSEPSFPALQEATVAARTVTFDYTRSGAAEPQTRRVDPWALTSWHGRWYLTGYDLDRAGQRIYRLSRISSAVRTGGEITHQRPEDLDPQGAVARFAQGDRPTTVAVVRVRTGAGHALRRRARASTDAGEGWDRLEVEHSSTHALADELAGYGGDVVAESPEELVTAVRSRLEGVLASLGGAR
>NZ_CP044548.2|WP_123091769.1|813219_814182_+|WYL-domain-containing-protein
MSPRTPAEPATTRVSRLLTMVPWLVSRQGIALSEAAEGLGVSEQQLRDDLDLLFMCGYGPMTDELIDVSYEQGHVYIDNAETISRPLRLGVAEATTIIVGLRALEASGVGPSDAVRRALATLEQATGSLPGIDRVGVVAEGERDHEVLQSASSAVQQRRRVHLTYLVPSRDERTERDVDPMRVVALDGHWYLEGWCHLAQDTRLFRLDRVEAIELLDVDGTPPPQAVSRDLSQGAYSGAPDDRVVTLLLRPRARWVAEYYPTLSQEEVGEDLRVRLTARDDAWLARLVLGCGGHAVLEAPQPAVDAVRARALAALSGYPA
>NZ_CP044548.2|WP_123091770.1|814245_814548_+|twin-arginine-translocase-TatA/TatE-family-subunit
MPNLGPMEIVVIAIVILVLFGFKKLPDAARSLGKSARVFKSEVNEMKEEDRAREEAKKARESGTITSAGTPVRDDVTHRQGDAMIDETKPRTDNTSGPAV
>NZ_CP044548.2|WP_123091771.1|814624_815404_+|twin-arginine-translocase-subunit-TatC
MPLKAHFIELRRRLVIAAAAVVVGTVVGWIYYDPIYEHLSSPFREYKRMHPESVIALNFANPTAAFSQQLSISIFAGILMTSPIWLWQIWAFVVPGLTKREKRISGAFFSATVPLFAAGCAFGYYTLPKALIILYGFTPDEDTSSNIQSTTDYFTFVMRFIFAFGASWLLPVVLVALCSIGVITGRQMLRAWRPAVLLIFVASAIITPTPDPFTMFLLAGPLVILFFGACGIGMLITRKREQARPAWLDTPEDQASALD
>NZ_CP044548.2|WP_123091772.1|815420_816317_+|diacylglycerol-kinase
MSSRRIGLLVNPTAGKNAGARVGTTVADLLERGGAEVVDLTGLDARRAEAKARRAVRDGEVDTLVVAGGDGAVGLGVNICAETEVPLGVVAVGTGNDNARELGLPVRDVEAAVERVLHGSARAVDLGRVRSTDASQQRWYLGVLCGGFDALVNERANTMRWPRGPARYNLAIARELPTFAPIPYTLTLDGELSHPRAMLVCVGNGRAYGGGMRVTPDADMADGLLDVLVVDEISVPELLRVFPKVFRGAHLGHPAVSVHRARSVRLDAPGVVAYADGERLYPLPVDVDVVPGAVRILI
>NZ_CP044548.2|WP_123091773.1|816343_819079_+|DEAD/DEAH-box-helicase
MSDAVDAFAAGVDFPLDPFQIEGCEAIAAGHGVLVAAPTGAGKTIVGEFAVHLALQRGQKAFYTTPIKALSNQKYHELAARHGHAQVGLLTGDTSINGEAPVVVMTTEVLRNMIYAGSSTLEGLGFVVMDEVHYLADRFRGAVWEEVIIHLAPSVQLVSLSATVSNAEEFGDWLDEVRGGNVVVVSEERPVPLWQHMQVGKEVYDIFVDGATPSDEADRWRVNPLLMDAVRSASRSGEDGPARGRGGRDRDRRGRGGRPQGGARQRFGGGASRTEVITQLDREGLLPAITFIFSRVGCEGAVGQLLGNDVRLISAAEGERNRRTLEERSAVLEGEDLTVLGYHQLLAGLERGYAPHHAGMLPIFREVVEELFTAGRVKAVFATETLALGINMPARTVVLEKLVKFNGEAHVEITPAEYTQLTGRAGRRGIDVEGHAVVVWSRGMDPLSVAGLASTRTYPLRSSFAPTYNMAVNLVATVGRQTAREILESSFAQFQADRAVVGLASKVRSQQESLEGYAEAMHCELGDFREYAQIRHRISDLEKSGRKQRSATRRAETAVSLDSLETGDIIRIGGRRSGLAVVVIPARPYKGQSGEPMVLTEHKQVRRLTTSDLDGPVTPFGKLAVPRSFNPRSARHRTDLATTLRVKAPHEGAPSIRREAKEAAGGEDARLVRLRQELRAHPCHACPDREEHARWSERWWRLKREQSALQRTVDSRTGSVAARFDRVVSVLVDLGYLDEGGDAVSADGARLRRLYSEKDLLAAECLRAGTWKQLTPAELAAAVSMLVYEPRRDDADLMPRIPTDGLAIAWEDMQERWRDIEAREHTAGLDPTDPPDAGIAWQVHRWASGRRLDEVLLDSDLTAGDFVRRCKQIVDLLDQIAKASEEDRLRSTARKAIDAVMRGVVAADRID
>NZ_CP044548.2|WP_123091774.1|819131_820073_-|5'-3'-exonuclease
MPSATPRLLLLDSASLYFRAFYGVPARAEAPSGIPTNAVAGFVDMIATLVGRYRPTHVAACWDDDWRPQWRVDAIPTYKAHRVAEDAAEGEEVPDELGPQVPVIAQCLEVLGVPKVGAAHYEADDVIGTLAHHYRGVMPVDVVTGDRDLFQLVDDASSTRVIYTARGGVRDPDVVDQGYLRTKYDVPTGDAYADMAVLRGDTSDGLPGVAGIGEKTAARLIAAHGSLEGIRAAIASGDPSIKGAQRARLEAGSDYLDAAPRVVAVARDVPVTDVDLTIGPELPDPAGMSRLALDHGIAGPLGRAAAALYPQAD
>NZ_CP044548.2|WP_068275787.1|820127_820553_+|Lrp/AsnC-family-transcriptional-regulator
MEEADQRIVDLLVVDGRMSYTDLGRAIGMSTSAVHQRVRRLEERGVIRGFTAQVDHAQAGRPLTAFIAVEPLDHRAPDDIPQRLRDVADVESCYSVAGDANYLLKVRVGTPQDLEALIATIRAKAEVSTRTTVVLSTPWED
>NZ_CP044548.2|WP_123091775.1|820604_822197_+|apolipoprotein-N-acyltransferase
MPETPFAPPAWVRAVLAVAGGLLVWLTFPDHGIHLAGVPGVALVGLALWGVRARVGFGLGMLAGWATFLPTLHWSGIFVGAMPWVALSTVQALYVAVMGAVLAAVQRPLLARGRVVLAALALPVLWVLQELVRGTVPFGGFPWARLAFGQADSPLARWAWLGGAPLISLVVALLAVPLVLLVVRRTLRAALLVPVAVALGLTGLLLPVHAEAPEGSTPARIGMVQGNVPRAGLDFNAERRQVLDNHVTGTEELGRSGERLDLVVWPENSSDIDPLRNPDAAAQVQRALDAVDVPVVVGAILDEPSPEVSNASLLYEPGRDAPTARYVKQHPVPFAEYVPYRDFFRLFSDKVDLVRVGFAKGPGPQAFPVEGSAGGFSVVPTICFEVAYDGLMREAVHHAEDGGLPSVLLVQTNNATFGYTAESTQQLAISRIRAIEHGRPVAHVSTVGVSAVIAPDGSVTQPTELFTAAQVVGTFDARTGLTPSDRLGPWVEIGSALALVLLVVAGRLRGRRADKVDTSPKTKLESSARA

Crispr_ID: NZ_CP044548_6

• CRISPR_ID: NZ_CP044548_6
• CRISPR_location: 935615-935687
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_6

Consensus_repeat	Method
CTCGCTGGCGCGCGCACCTCGAC	CRISPRCasFinder

spacers of NZ_CP044548_6

>6.1|935638|27|NZ_CP044548|CRISPRCasFinder
GAGCGAACGGGGCAGGTGGTCTCGAGG

CRISPR arrays and Neighbor proteins around NZ_CP044548_6

CRISPR arrays

The CRISPR arrays of NZ_CP044548_6

>merge|NZ_CP044548|6|935615-935687|CRISPRCasFinder
CTCGCTGGCGCGCGCACCTCGACGAGCGAACGGGGCAGGTGGTCTCGAGGCTCGCTGGCGCTCGCACCTCGAC

>NZ_CP044548|6|6|935615-935687|CRISPRCasFinder
CTCGCTGGCGCGCGCACCTCGAC	GAGCGAACGGGGCAGGTGGTCTCGAGG
CTCGCTGGCGCTCGCACCTCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_148041570.1|933715_935008_-|DUF222-domain-containing-protein	unknown	unknown	gnl|CDD|367155
NZ_CP044548.2|WP_123091854.1|926811_927045_-|superinfection-immunity-protein	unknown	unknown	gnl|CDD|379585
NZ_CP044548.2|WP_123091871.1|943735_944905_+|ScyD/ScyE-family-protein	unknown	unknown	gnl|CDD|380207
NZ_CP044548.2|WP_123091864.1|936677_937526_-|4-amino-4-deoxychorismate-lyase	unknown	unknown	gnl|CDD|223193
NZ_CP044548.2|WP_123091989.1|945354_946263_-|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NZ_CP044548.2|WP_123091858.1|930453_931386_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP044548.2|WP_123091860.1|932980_933586_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|223532
NZ_CP044548.2|WP_123091855.1|927083_927791_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP044548.2|WP_148041571.1|942438_943524_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_CP044548.2|WP_163562374.1|927839_929156_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223737
NZ_CP044548.2|WP_123091857.1|929198_930422_+|MFS-transporter	unknown	unknown	gnl|CDD|340882
NZ_CP044548.2|WP_123091853.1|926061_926712_+|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|225462
NZ_CP044548.2|WP_123091866.1|938618_939632_+|TIGR03885-family-FMN-dependent-LLM-class-oxidoreductase	unknown	unknown	gnl|CDD|274834
NZ_CP044548.2|WP_123091862.1|935107_935584_+|N-acetyltransferase	unknown	unknown	gnl|CDD|224168
NZ_CP044548.2|WP_123091867.1|939628_941314_+|trehalose-synthase	unknown	unknown	gnl|CDD|200473
NZ_CP044548.2|WP_123091863.1|936105_936681_-|TIGR02611-family-protein	unknown	unknown	gnl|CDD|131660
NZ_CP044548.2|WP_123091859.1|931382_932975_+|hypothetical-protein	unknown	unknown	gnl|CDD|226089
NZ_CP044548.2|WP_123091868.1|941313_941862_+|sodium:proton-antiporter	unknown	unknown	unknown
NZ_CP044548.2|WP_123091865.1|937522_938620_-|chorismate-binding-protein	unknown	unknown	gnl|CDD|366092
NZ_CP044548.2|WP_123091869.1|941866_942349_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_148041570.1|933715_935008_-|DUF222-domain-containing-protein	gnl|CDD|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	3.12061e-20
NZ_CP044548.2|WP_123091854.1|926811_927045_-|superinfection-immunity-protein	gnl|CDD|379585	pfam14373, Imm_superinfect, Superinfection immunity protein. This family includes the E. coli bacteriophage T4 superinfection immunity (imm) protein. When E. coli is sequentially infected with two T-even type bacteriophage the DNA of the superinfecting phage is excluded from the host, into the periplasmic space. The immunity protein plays a role in this process.	4.14687e-12
NZ_CP044548.2|WP_123091871.1|943735_944905_+|ScyD/ScyE-family-protein	gnl|CDD|380207	NF033206, ScyE_fam, ScyD/ScyE family protein. This family includes ScyE, a protein involved in scytomenin biosynthesis and export, and its paralog ScyD. Some members of the family contain a C-terminal PEP-CTERM domain that predictions anchoring to the outer membrane.	1.28989e-45
NZ_CP044548.2|WP_123091864.1|936677_937526_-|4-amino-4-deoxychorismate-lyase	gnl|CDD|223193	COG0115, IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism].	9.85653e-67
NZ_CP044548.2|WP_123091989.1|945354_946263_-|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	1.70048e-32
NZ_CP044548.2|WP_123091858.1|930453_931386_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.09265e-89
NZ_CP044548.2|WP_123091860.1|932980_933586_-|GNAT-family-N-acetyltransferase	gnl|CDD|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	1.99431e-06
NZ_CP044548.2|WP_123091855.1|927083_927791_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.02309e-45
NZ_CP044548.2|WP_163562374.1|927839_929156_+|FAD-binding-oxidoreductase	gnl|CDD|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	9.04103e-44
NZ_CP044548.2|WP_123091857.1|929198_930422_+|MFS-transporter	gnl|CDD|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.57046e-60
NZ_CP044548.2|WP_123091853.1|926061_926712_+|NAD(P)H-binding-protein	gnl|CDD|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	1.88938e-55
NZ_CP044548.2|WP_123091866.1|938618_939632_+|TIGR03885-family-FMN-dependent-LLM-class-oxidoreductase	gnl|CDD|274834	TIGR03885, putative_dehydrogenase_protein, probable non-F420 flavinoid oxidoreductase. This model represents a clade of proteins within the larger subfamily TIGR03557. The parent model includes the F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554) and many other proteins. Excepting the members of this family, all members of TIGR03557 occur in species capable of synthesizing coenzyme F420. All members of the seed alignment for this model are from species that lack F420 biosynthesis. It is suggested that members of this family bind FMN, or FO, or a novel flavinoid cofactor, but not F420 per se. [Unknown function, Enzymes of unknown specificity].	1.06066e-166
NZ_CP044548.2|WP_123091862.1|935107_935584_+|N-acetyltransferase	gnl|CDD|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	5.19244e-44
NZ_CP044548.2|WP_123091867.1|939628_941314_+|trehalose-synthase	gnl|CDD|200473	cd11334, AmyAc_TreS, Alpha amylase catalytic domain found in Trehalose synthetase. Trehalose synthetase (TreS) catalyzes the reversible interconversion of trehalose and maltose. The enzyme catalyzes the reaction in both directions, but the preferred substrate is maltose. Glucose is formed as a by-product of this reaction. It is believed that the catalytic mechanism may involve the cutting of the incoming disaccharide and transfer of a glucose to an enzyme-bound glucose. This enzyme also catalyzes production of a glucosamine disaccharide from maltose and glucosamine. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP044548.2|WP_123091863.1|936105_936681_-|TIGR02611-family-protein	gnl|CDD|131660	TIGR02611, Putative_membrane_protein, TIGR02611 family protein. Members of this family are Actinobacterial putative proteins of about 150 amino acids in length with three apparent transmembrane helix and an unusual motif with consensus sequence PGPGW. [Hypothetical proteins, Conserved].	2.54849e-17
NZ_CP044548.2|WP_123091859.1|931382_932975_+|hypothetical-protein	gnl|CDD|226089	COG3559, TnrB3, Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane].	1.49071e-94
NZ_CP044548.2|WP_123091865.1|937522_938620_-|chorismate-binding-protein	gnl|CDD|366092	pfam00425, Chorismate_bind, chorismate binding enzyme. This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.	1.45256e-89
NZ_CP044548.2|WP_148041571.1|942438_943524_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.01701e-12

Protein sequences

>NZ_CP044548.2|WP_123091862.1|935107_935584_+|N-acetyltransferase
MTAADWPAVERIYREGIATGLATFETQPPTWERFDEHRLPAPRLVATGERGEVVGWAAVTPVSTREVYRGVVEHSIYVASAARGQGVGGRLLADLLAAADESGIWTVQATLFPQNLSSLALHHAHGFRTVGTRERIALMTHGPLAGTWLDTVLVERRR
>NZ_CP044548.2|WP_148041570.1|933715_935008_-|DUF222-domain-containing-protein
MAAIATARWGGAGVLPGLRDALRSLQLQHDLGDETWRLADDEVHDALALVGQLRQLVDVAEVAVAREGLERGLPAERSWSAHDWVARSEAARAPAPDVHHVARVLRVAKGQTRVPEVTAAFTAGDLPLTKADQLVRLETQVAPVAEPESLAEAMRILLDGARDDVVPTGPDGHGPHERISGLTERQLAQAVTRTGRLLRPVEDLEHDDRRARAARALFRHEGPAGLTSYRVVLDPEGAAVVDAALAALSGPVTGPEGERDERSPAQRRAEALLEIIRRGVSAPGEVPRTDKAQVHVLIPLSTLLGDDAHGGATTATGQVLAPSVARRMACDAGIVPVVLGGSGEVLDMGRVVRLFTPGQQRVLWHRDQGCTYPGCTVPPQWCDAHHVRWWSRGGLTDVSNAALLCQRHHTRVHQLDLMATVASTGVTWHL
>NZ_CP044548.2|WP_123091860.1|932980_933586_-|GNAT-family-N-acetyltransferase
MSHDVRPATPVDLPEAALTLVRAFEHYPWTRWSIPADDHLARLEELQLLYLAHALRHGVVLVDDEVHGVGAFLPPGAPDPDDATQGRVVELMDDRLPVVMSADLPPRPAGAWDLATLGVRPGSAGRGLGSAVLAEGLRRVDGMMSSVALETSDARNVRLYERHGFVVTGSTEIPDGPVVWSMCREATSPAGTGTGSGPTAG
>NZ_CP044548.2|WP_123091859.1|931382_932975_+|hypothetical-protein
MNLGLTGTGELARLVLRRDRVRLPAWVLGLGGLVAWSAVGVQSVYDTPAKVAGYAATVGTSPVSRLMSGRQAGIDTIGGITANEISQVAQLGVCLMVTFLVVRHTRGDEESGRSELLRSGVVGRHAATLTALLYAVAAAVAVGGITAASMLGVGLGTTGTVAYAVGLVLLGACFAAVALVAAQLTSSARTALALAGAAVGVAYLVRGLGAIRDDALVWLSPFGWAQEMQAFGTERWWPAGLLAVATAALLVGAAWLETRRDHGGALLHPRPGPARASRWLASPLALVLRVQRGALVGWVVGLAALAVIYGAVIPTIPDLLASNPEIGQYIGASGSAQEALVDAFVRYVLLFLAVVSTAFGVACVTRLHGEEESGRGELVLAAAVSRTRWVGATVAVACAGSLLLLLTSGLGLVVGYVLGGGEGVSPTEVVGGQLSYLPAVLVVVGVAVLLVGARPRAVPLAWVVVAAVAVLALLGQSLGLPEGVERVSPFAVLPGVPVEPFDPVPGAVELVVVALLVGVGTWAYRRRDLG
>NZ_CP044548.2|WP_123091858.1|930453_931386_+|ABC-transporter-ATP-binding-protein
MELAVELSDVVKTFGRARALDGLDLQVRTGEVHGFLGPNGAGKSTTMRVLLGLIRVDSGRARLLGFDPWPDPAALHRRVAYVPGDVTLWPSLTGGEVIDLLGRLRGGLDRRRLDELLERFELDPTKRTRTYSKGNRQKVALVAALAGHADLYLLDEPTSGLDPLKEAEFQRCVREAAADGATVLLSSHVLAEAEALSDRVSIIRAGRLVRSGSLAELRQLTRTTVSAQVTSPPGALADVDGVHHLRVDGDRVSLDVDPDHLDGVLEALSALGVRSLVAHPPTLEELFLRQYADMDTDTPGAPDDRPSDLS
>NZ_CP044548.2|WP_123091857.1|929198_930422_+|MFS-transporter
MRPTSTSPDASWRGHDRGSREYRRILVALLGAGVATFAQLYSPQGVLPLLAGDLDIDPARASLSISAATTGLALSVLPWSVLADRVGRVSAMRLALVSATVFGLVMPWCPWFEALVVVRVLEGVALGGIPGVAVTYLSEEVSARSAAVAAGTYVSGTTVGGLLGRLVAAPVADVAGWRVGTFAVAVLAAVATAVFFVVTPPPQGFRPRRSSVGTTLQAVRRHLRDRHLVALYAQGLLLMGGFVAVYNYLTFRLEAPPFLVPVGAASLLFLAYLAGTVSSRVAAGLVARLGRRAVLLASTGVMVAGTLVTLADSLVVVIGLVVLTAGFFGAHSVASGWSGTAARGDRSQSTSLYTLFYYGGSSIFGYLGGLAWSALGWGGLVTMVVALCCAAALWAALGIREVLPRSG
>NZ_CP044548.2|WP_163562374.1|927839_929156_+|FAD-binding-oxidoreductase
MAQQSVPSSISGRPRRVGVVVVGAGVVGASVARDLARRGTEVVVVDGAPGIGGGCSYANAAILAPGHVTPLATPALLREAPVQMLRRPAAVAVRPARGLAPWLGRLAASAAPHRSGPGGHLLRALAHESTTLHRELADRGLSPTLRGTGAVDVYLREARGAALSPEQLRALEPMLGEVAGGSHDEDEWTVESRSYVSATLEDAVAHGAELHFGTDVRALVPHADGGHHVVTDRTTVHADHVVLAAGVESSVLAAQVGVELPLRGGRGYVVDVAATESDLRMPVRIKEHRVVVTPLEDRVRVCGSIEFGDESRPADLRRADALLEVATRVLPDLAGREVLDRWAGERPCTPDGMPLVGTSRVAPGLAVATGHGMWGMILAPVTARLITEALLDGPALPTDGWLHPDRFTRGSHRRSLPGGARAGLARRGRVDGGVRAAS
>NZ_CP044548.2|WP_123091855.1|927083_927791_-|response-regulator-transcription-factor
MIIGSTTAVVVRSSVRTDVDEGGEGVSPPIRVLLVEDHPVVLRGLQAMLREHDDVAVVGEAGTAAEALSQASRLQPDVVVLPVRLGGIRASIELCRSIKTACTARVVVFTSFTRTVDVQMAMLAGADALVAKTVSADALLAALRQVRAGGEVLDLGPGADRPTPRLTPAEPLTDREAQILQLVLDGLTNPQMAQRLRIEVTTVRTHMRSILRKLGLESRRDLVQPAHPGLDTGEG
>NZ_CP044548.2|WP_123091854.1|926811_927045_-|superinfection-immunity-protein
MPTVITDRTSRPVSSLVAIVVAVVTAGYMLPWAIAAVRGNRNMWSVFWVNLLLGWTVVGWVVALVMSIREHRVLGVR
>NZ_CP044548.2|WP_123091853.1|926061_926712_+|NAD(P)H-binding-protein
MTRITVLGGTGYTGRHIAATAAAKGHDVTTWSRSAPAEPVEGATHRTGDLSDPAVVAAAVEGADVVVSAVSPRGELAEQGALRGILATAARQAQERGVRLGVIGGAGSLHVAEGGPLLVDTPDFPEAFAPEARELTAVLQDLRASDEALDWFFLSPAAGFGAYAPGEATGSYRTGGDVLLADEQGESFISGEDLALAVVDEIEQPAHRRARFTVAY
>NZ_CP044548.2|WP_123091863.1|936105_936681_-|TIGR02611-family-protein
MTSMEATRGEQQEEERRGLGLDAQGHRRPYRAIRRDQHELVREELLERFGENQTIDPEEDSIRWRRAVRLNPVLGPVYRIGVFVAGLALIVVGIPMVPLVGPGWVVIFVGLFLWSTEYMWARRVTQFVKAEVKSFEQWARHLPLAAKIPLVMVSVAIGWLCFYLALLVTGLPGWTPDVVEEYLRMLPGLGA
>NZ_CP044548.2|WP_123091864.1|936677_937526_-|4-amino-4-deoxychorismate-lyase
MSMGVTVWVNGELVDGGQASLTALDHGLTVGDGGFETCKVVDGVVFGRTRHLRRLERTLEGLGLTGFDADHLDEGVEAVLAAGGPMPLGRLRWTVTGGVGPLGSDRSDTPLTYVVGLVPASPLPSHAHVATVPWTRNERAATAGLKTTSYAENVIALARAKSQGADEAIFLNTRGELCEGTGSNVFVVRDGVVLTPPLESGCLAGITRAVTIEWCREAGLEVREETLPADAMETSDEAFLTNTMRDVQPIATVDGRALATQTPVTDQAAAIFATRSAERMDP
>NZ_CP044548.2|WP_123091865.1|937522_938620_-|chorismate-binding-protein
MGTTHHTSAPSWGLAACAVQPRGRPYAAAVEYARFGRRLLIDPVAVSTDLADLDDGGQWAVVVTFEGEVTAVRFARAEQTSDAPATGPWVPPGRWSSSMSEGEYLAGVERVREHVAAGTVYQVNLCRVLTAPLAPQAHLPALAAVLEEGNPAPFAGLVHVPSAGLDVVCASPEAYLLRDGDRVVSRPIKGTGRVPSDLGAKDHAENVMITDLVRNDLSHVAVPGTVDVEALCALEEHPGLLHLTSDVAARLRPGVGWAELVGATFPPGSVSGAPKSSALQVIRELEPVRRGPYCGAIGWVDADAGRGELAVGIRTFYAEQGPAGRVLRFGTGAGITWGSDPGQEWRETELKAGRLVGLSSGRVGV
>NZ_CP044548.2|WP_123091866.1|938618_939632_+|TIGR03885-family-FMN-dependent-LLM-class-oxidoreductase
MPVIGHHCSHEQISPRQLLLDVQHAERAGFTAAMSSDHLAPWSARQGESGFAWSWLGAALATTDLPFGVVNAPGQRYHPAILAQAIATLGQMYPGRFWAALGSGEAANEHVTGQGWPRKEIRDERLRECVDVIRRLLRGEVVSHDGHVVVDRAQLWTLADPVPRLVGPAVTPQTAARHADWADGLITVNQPVERLREVLAAYRDAGGRGPTRLQVHLSWAPTQEQAEAIAHDQWRSNTVGPPIAWDVDSVEGFDAIGEHVTRESVAEAVRISADPGQHVEWLQEYLEIGYDELYLHFVGQDQREYLDTFAEQVLPHLGPTRPETTPGTTQPDPKGAR
>NZ_CP044548.2|WP_123091867.1|939628_941314_+|trehalose-synthase
MNLTDTADLWWKHAVLYCADVQTFVDSDGDGCGDLTGMAERVDYLADLGITCLWLMPFYPTADRDDGYDITDFYGVDPRAGTPGHMVELVHLARSRGIRVIVDFVMNHTSDQHPWFKESRKSTDNPYRDWYVWRSSTPPDTSDQVVFPDQEDSIWELDERTGEYYLHNFYKTQPDLNIANPAVRDEIARTMGYWLQMGVSGFRVDAVPFLFAEDTLPESERKFPAYDPHEYLRSLRRFVSRRGGNVMLLGEVNLPYPEQKLFFGGTDADQLTTQFDFVGMQATYLSLARHDARPLAKALRSRPRLSDESQWASFMRNHDELTLDKLTDDERQEVFDAFGPEPQMQLFDRGLRRRLPTMLGGDMRRIRMAYSLMFSLPGTPVLFYGEEIGMGENLDIPGRLAVRSPMQWDPSGGFSQAPERQQVRPMTSGPWGPERINVADQRGDVDSLWRFVSRLIQRYRQSPEIGWSQVEVLRGTPRSVLAHVCRKDEWRMVALHNFSGEPVEISVTVPDLPDECSFVDLLTPGAPRRIEPGPKGVLETTIDGYGFLWLRVCSAQDTRVA
>NZ_CP044548.2|WP_123091868.1|941313_941862_+|sodium:proton-antiporter
MAKGEHEGSADGEDVAPGDGRDETATERFDRNWEELLQELRVVQTGVQILAGFLLTLPFQARFTVLEPHHRVIYLVAFCLALLATALLAAPVSAHRLLFRRHAKRELVAFGNRCAQGGMVSLALSLLAVLYLIVEVLLGTPAAVTALVVGAAVFLALWVVLPMRMGRAAGHAGSPPPSRSSS
>NZ_CP044548.2|WP_123091869.1|941866_942349_-|hypothetical-protein
MTQDPRREELAAHDERGTRDGETVEVAPTHGPEHDTEVHPHVSKSGERVVLNTIAGEDGTEAVRAQAAALLRVVGEAGGLTQDELTERVHEAMAATGAGDQPTVVARSVAEAIQRGIRSRLVIETDDGAVLGVYDAPADEVERVHPNVTDPAHEDRPFYT
>NZ_CP044548.2|WP_148041571.1|942438_943524_-|helix-turn-helix-transcriptional-regulator
MDRDLVRDRVVADVAVLARAQVDLETFAHEAMQSLQRAVPHDGWSLGTLDPASLMPTGVCLREGCAVAWSAHDREWARLEYGQDDPTSVLAMARSGCAALGVHDVTGGDLSRSPRMRDLMTPVLGCADELRALATDGHRSWGAVFLYRLRGHFEPWEVALVEALCPSFARAVRRGVLGMWAGRRTVTDDATPTMVVLDARGEVVLSSPGGVEQLVSLHHGDGAEASEGLLASLAAAAAATRATKGAHHPTTRVRLADGRWCTVHATPLGSPDGDLVGVTITESRPRELLPLVVDALGMTPRERDVLVLVVRGADTRSVAEQLHMSSHTVQDHLKAIFAKAGVHSRRELTALVLGDQLDPAW
>NZ_CP044548.2|WP_123091871.1|943735_944905_+|ScyD/ScyE-family-protein
MSSSRLRARHQHPGRRRGLRPVLAAAAAAVLGLSLAPPTSAARPPGDPQGHPRWVSTIDDSVLAPFQLAVEGRDVYATDGFLGTLTKYSRSGTKTVLARVEGGEIAGVDVAKGGRTWAYASTSSDGRSTLTIQSKGRPDVVADLGAYEQTVNPDQGVTYGIIAGGNPCAEEVFGGLTGGQATYTGIVESHPYAVAALPDGSWAVADAAGNSVLRVDRRGRISTLALAPRRPLLITTEIAASIGLPDCTVGVTYAFEGVPTDVEVGPRGRLYMSSLPGGPEDPSLGARGAVFTIGHHGAVTKVASGFLGATNLAVQGDTLYVAELFGGQVTAVHGRHRWAAYRMERPLAVEVSGRTMYLGQLADIDFETGTPRAPGSIVKVSLRHHHHHH
>NZ_CP044548.2|WP_123091989.1|945354_946263_-|YihY/virulence-factor-BrkB-family-protein
MSTRVRVRDGLESVPFALALVRLVRETVRICLRYRVTGLAAEAGFFALLSLPPLVLGLFGGVGYVGSAVGQSGVDDFTERIASYAGSFLTPQVIDDLLLPTVDEVFRAGRGELISIGFLLSVWSGSRVLNVFIDTISIMYGQSGIRGIVRTRAMSLSIYTLGLLFGVVMMPLVLVGPSAIGSLLPDPADWLVALYWPVVSVLVLAGVTTLFHLSTPQRDPWRRDLPGAALTLVLWVLSAWLVRTLVAGSLGGTSIYGPLSTPIILIVGLYAIAISVLVGAALNAAVRSLWPHSAADRSIAQA

Crispr_ID: NZ_CP044548_7

• CRISPR_ID: NZ_CP044548_7
• CRISPR_location: 1246766-1246866
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_7

Consensus_repeat	Method
GGGGCGAAGGGGTTGTTGCCGGG	CRISPRCasFinder

spacers of NZ_CP044548_7

>7.1|1246789|55|NZ_CP044548|CRISPRCasFinder
ACGGGGGCCGCCGGAGCCGCCACCGCCGTCACGACGGGTCCCCATGCCCTGCGAG

CRISPR arrays and Neighbor proteins around NZ_CP044548_7

CRISPR arrays

The CRISPR arrays of NZ_CP044548_7

>merge|NZ_CP044548|7|1246766-1246866|CRISPRCasFinder
GGGGCGAAGGGGTTGTTGCCGGGACGGGGGCCGCCGGAGCCGCCACCGCCGTCACGACGGGTCCCCATGCCCTGCGAGGAGGCGAAGGGGTTGTTGCCGGG

>NZ_CP044548|7|7|1246766-1246866|CRISPRCasFinder
GGGGCGAAGGGGTTGTTGCCGGG	ACGGGGGCCGCCGGAGCCGCCACCGCCGTCACGACGGGTCCCCATGCCCTGCGAG
GAGGCGAAGGGGTTGTTGCCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_083968753.1|1247611_1247956_-|YlxR-family-protein	unknown	unknown	gnl|CDD|377288
NZ_CP044548.2|WP_163562386.1|1251639_1252239_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP044548.2|WP_123092893.1|1235086_1236922_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|223953
NZ_CP044548.2|WP_148041602.1|1241284_1241842_-|DUF4190-domain-containing-protein	unknown	unknown	gnl|CDD|379388
NZ_CP044548.2|WP_123092806.1|1247948_1249007_-|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
NZ_CP044548.2|WP_123092812.1|1239253_1240207_-|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl|CDD|235113
NZ_CP044548.2|WP_123092891.1|1250555_1251464_+|phosphotransferase	unknown	unknown	gnl|CDD|309685
NZ_CP044548.2|WP_123092889.1|1254611_1256252_-|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|376752
NZ_CP044548.2|WP_123092804.1|1249701_1250559_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_068274885.1|1240203_1240647_-|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl|CDD|234787
NZ_CP044548.2|WP_123092807.1|1243229_1244477_+|Dyp-type-peroxidase	unknown	unknown	gnl|CDD|273606
NZ_CP044548.2|WP_123092814.1|1237096_1238227_-|rod-shape-determining-protein-RodA	unknown	unknown	gnl|CDD|274033
NZ_CP044548.2|WP_123092811.1|1240717_1241053_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123092805.1|1249014_1249569_-|ribosome-maturation-factor-RimP	unknown	unknown	gnl|CDD|234627
NZ_CP044548.2|WP_123092808.1|1242639_1243233_+|copper-chaperone-PCu(A)C	unknown	unknown	gnl|CDD|377298
NZ_CP044548.2|WP_123092813.1|1238243_1239203_-|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl|CDD|235536
NZ_CP044548.2|WP_123092809.1|1241975_1242542_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123092800.1|1256389_1260100_-|cobaltochelatase-subunit-CobN	unknown	unknown	gnl|CDD|235663
NZ_CP044548.2|WP_123092802.1|1252277_1253762_+|cobyric-acid-synthase	unknown	unknown	gnl|CDD|234838
NZ_CP044548.2|WP_123092801.1|1253758_1254556_+|precorrin-6A-synthase-(deacetylating)	unknown	unknown	gnl|CDD|381170

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_083968753.1|1247611_1247956_-|YlxR-family-protein	gnl|CDD|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	4.97809e-22
NZ_CP044548.2|WP_163562386.1|1251639_1252239_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.37352e-30
NZ_CP044548.2|WP_123092893.1|1235086_1236922_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|223953	COG1022, FAA1, Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism].	0
NZ_CP044548.2|WP_148041602.1|1241284_1241842_-|DUF4190-domain-containing-protein	gnl|CDD|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	2.44193e-07
NZ_CP044548.2|WP_123092806.1|1247948_1249007_-|transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
NZ_CP044548.2|WP_123092812.1|1239253_1240207_-|tRNA-pseudouridine(55)-synthase-TruB	gnl|CDD|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	2.38525e-142
NZ_CP044548.2|WP_123092891.1|1250555_1251464_+|phosphotransferase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	9.29171e-28
NZ_CP044548.2|WP_123092889.1|1254611_1256252_-|5,6-dimethylbenzimidazole-synthase	gnl|CDD|376752	pfam02277, DBI_PRT, Phosphoribosyltransferase. This family of proteins represent the nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) enzymes involved in dimethylbenzimidazole synthesis. This function is essential to de novo cobalamin (vitamin B12) production in bacteria. Nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (CobT) from Salmonella enterica plays a central role in the synthesis of alpha-ribazole-5'-phosphate, an intermediate for the lower ligand of cobalamin.	1.52201e-71
NZ_CP044548.2|WP_068274885.1|1240203_1240647_-|30S-ribosome-binding-factor-RbfA	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	5.52107e-40
NZ_CP044548.2|WP_123092807.1|1243229_1244477_+|Dyp-type-peroxidase	gnl|CDD|273606	TIGR01412, Probable_deferrochelatase/peroxidase_EfeN, Tat-translocated enzyme. This model represents a small family of proteins with a typical Tat (twin-arginine translocation) signal sequence, suggesting that the family is exported in a folded state, perhaps with a bound redox cofactor. Members of this family show homology to Dyp, a dye-decolorizing peroxidase from Geotrichum candidum that lacks any typical heme-binding site.	7.85479e-80
NZ_CP044548.2|WP_123092814.1|1237096_1238227_-|rod-shape-determining-protein-RodA	gnl|CDD|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	8.49908e-114
NZ_CP044548.2|WP_123092805.1|1249014_1249569_-|ribosome-maturation-factor-RimP	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	5.66618e-33
NZ_CP044548.2|WP_123092808.1|1242639_1243233_+|copper-chaperone-PCu(A)C	gnl|CDD|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	7.00619e-33
NZ_CP044548.2|WP_123092813.1|1238243_1239203_-|bifunctional-riboflavin-kinase/FAD-synthetase	gnl|CDD|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	3.0426e-123
NZ_CP044548.2|WP_123092800.1|1256389_1260100_-|cobaltochelatase-subunit-CobN	gnl|CDD|235663	PRK05989, cobN, cobaltochelatase subunit CobN; Reviewed.	0
NZ_CP044548.2|WP_123092802.1|1252277_1253762_+|cobyric-acid-synthase	gnl|CDD|234838	PRK00784, PRK00784, cobyric acid synthase.	0
NZ_CP044548.2|WP_123092801.1|1253758_1254556_+|precorrin-6A-synthase-(deacetylating)	gnl|CDD|381170	cd11643, Precorrin-6A-synthase, Precorrin-6A synthase (also named CobF). Precorrin-6A synthase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways in bacteria. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model represents CobF, the precorrin-6A synthase, an enzyme specific to the aerobic pathway. After precorrin-4 is methylated at C-11 by CobM to produce precorrin-5, CobF catalyzes the removal of the extruded acyl group in the subsequent step, and the addition of a methyl group at C-1. The product of this reaction is precorrin-6A, which gets reduced by an NADH-dependent reductase to yield precorrin-6B. This family includes enzymes in GC-rich Gram-positive bacteria, alpha proteobacteria and Pseudomonas-related species.	1.71058e-114

Protein sequences

>NZ_CP044548.2|WP_123092807.1|1243229_1244477_+|Dyp-type-peroxidase
MTPGSSGGHGLRRRTLLGSGVGAALAGSAAVLTAAGPARPVAAAAEQTSPGPRTVAFYGDRQAGVTTPPQTHTRWVALDLARGSDLADLRRVLRMWTQDLARITQGVPPLADHTPELTLDPAHLSVTVGLGRSAFARLGRLDLAPPWLRDLPSFATDALQDRWSGGDVVLQIGSSSLEATARVQRALVRAAGSTTTSRWTQAGHRGPSPEPSWATQRNAFGQVDGTVQPAVDGLDDDLLWRDASSGAWEHASTLVLRRVAMNLDTWEQLDGHAKEAAIGRRLGDGAPLTGGGERTPPDLHATDADGLTVIDPSSHMARAMPREPWERFLRRPYSFELPGADDVGTLTRAQTARSAHGLLFAAYCADAHRQYVPVQRRLAEADLLNIWTVTTGSTLVAVLPGVHPGEALGERVLDG
>NZ_CP044548.2|WP_123092808.1|1242639_1243233_+|copper-chaperone-PCu(A)C
MRTTHRRALRALVGLAAVTTLAACGSGKTTSTTTASSSSAASTSTPALTVTDGWVKAVDASQDMTAAFGTLTNTGDEDVVITGGRSDLAGMVEAHVMSKDENGAMVMEEAKDGHTVPAGGELELTPGGAHLMLMDLSSDVVAGEDYVVTVTTADGQEVDLTFAGREFSGAEEEYAPDMPGMSHDGHGETSATSSSSR
>NZ_CP044548.2|WP_123092809.1|1241975_1242542_+|hypothetical-protein
MTTGRLPVVRAVRSLALTTSAVGAGLLAHWHAGGTTPHPVALLVLLLVLTVPVARLSARRVSPAVATVVLGAGQGAIHLLGALGGTTSSHASSHGGHEVVHLGPLPAGSTDGGGLTMLGLHLVVTLALAALWSRGEQALFAVVRRLRPPALPRWSVPGAPAVLVAVVAPRARSLTRWHPSRAPPLPVS
>NZ_CP044548.2|WP_148041602.1|1241284_1241842_-|DUF4190-domain-containing-protein
MTTPPPPPGSGGNQPYDPTGSSPYPSGSGSTPGSGSTPSSGSTPGSGSTPPPSGPSGSSYPSAPGASYGSSGPGAPQGNPYGSAPNQYGAPKSGSDSTKILALVSMGFGIVGVVLCCCWALPIFPIVALVTGFIARNQTKAHPRPDLKTFITVGLATGALGLVIAVLYWILVAAGVIDLNATYNY
>NZ_CP044548.2|WP_123092811.1|1240717_1241053_-|hypothetical-protein
MPGTPYAQAGGAQSPGTPAPQILGIVSIVFGIVGIPASCCCWFIGWIFPVAALVAAVVGLTQARGAEDSRHRPLLVAGAVLGGTGLLLVAAAFVAGLLGTIPGLYDVPGDY
>NZ_CP044548.2|WP_068274885.1|1240203_1240647_-|30S-ribosome-binding-factor-RbfA
MADPARARKIADRIKEVIAGNLESIVKDPDLGFVTITDVRVTGDLQHASVFYTVFGDDAQRERSGRVLEANQGKLRSFVGRQLGIRLTPTLELIPDALPETASHLDDVLRQTRERDEQLAQSATGAQYAGEPDPYKKPREDADQSEG
>NZ_CP044548.2|WP_123092812.1|1239253_1240207_-|tRNA-pseudouridine(55)-synthase-TruB
MSRPASRPRRPFAGDGLVVLDKPAGWTSHDVVARCRGLYGTRKVGHAGTLDPMATGVLVIGVGRGTKLLTFLVGCDKEYTATIRLGQRTVTDDAEGEVTASVDAAAVTDDAVAQGVAALTGDIEQVPSSVSAIKVDGERSYARVRSGEQVDLPARPVTVSELVVLDRRAATADDGTAVVDLDVRAVVSSGTYIRALARDLGEALGVGGHLTALTRTRVGGYHLDDAEDLAELTARAEDLEASMPLVPLADAAAASLAVRRLDEAQARALGYGQRIDSEQPGRTEPVAAIGPDGTLVAVLDESGARVRAHVVLAPAGS
>NZ_CP044548.2|WP_123092813.1|1238243_1239203_-|bifunctional-riboflavin-kinase/FAD-synthetase
MQRWTTPEATPDALRPCVATFGNFDGVHRGHRAILDRLLAEGRERGLPTVTVTFDPHPVEVLHPERAPELIAPGALRDELLGELGVDGVLVVPFTWEYAQTTAEDFVVSTFVEGLGATCLVVGADTKGYGRGYTGDVDLLRTLGEQHGFEVVVIDDVGDGERWSSSAVRRLLAEGDVAAAGEILGRPHRVVGEVVHGEHRGRELGYPTANMSQDSLGILPADGVYAGWLVRRGLPEGHPDRRLPAAVSVGTNPTFDGVRRVLESYVLDRTDLDLYGEQVGVELVERIRPTLRFSSVDELLDAMSTDVERTRAVLGVTAP
>NZ_CP044548.2|WP_123092814.1|1237096_1238227_-|rod-shape-determining-protein-RodA
MSPTATARRPGGRVRELLLRGDVVLVVTALVLSLVGALLVGSATRADAGSTVFVKHLVNLAVGLVMAGALLRLDRHTLRALAPVLYLLSVAALVVVLGPLGSTVNGSRSWVELPVGLSVQPSELAKVALCVALPMVLADAAERGRAPTTRDVLVSGAVVGVPVLLVLAQPDLGSALVLLALSVGVLVASGARWPWLAGLALVAGGAVLAAFTTPVLSGYQRDRLTTFLDPSADPLGIGYQTQQVREAIGSGGLLGSGLGAGELTQSGRIPFQETDFVFSVAGEELGFLGGAVIIALYGLLVARIGLAAARADHFGRLVCVGVATWFGVQVVENVGMNLGVMPVTGLPLPFLSYGGSSMFACWLAVALVVSAAPRER
>NZ_CP044548.2|WP_123092893.1|1235086_1236922_-|long-chain-fatty-acid--CoA-ligase
MPSDETYDAAVLANPAPSVGHLLRERIAATPDRAAYSYPEGVAWGEMTWAQLGDRVWRLAAGLVDLGVEAEERVAIACSTRIEWVLGDLAIMAAGAATTTIYPTTIADDVAYILDNSGSVVVIAEDAEQVAKLREVREVIPDVRTVVVVDPEGVERDDWVVTLDELEERGQAVLEATPGVVDERIEGTGPDSLATIIYTSGTTGRPKGVRLLHSAWTYQGAATTATGMMTQDDVQYLWLPLAHVFGKQLLMLTLATGMSTAVDGRIDKIVDNLAVVRPTFMAAAPRIFEKVYARVSLGMEAEGGAKLKLFRWASDLGRARADAEQEGRSLSPVQKAQLAVADKLVLSKVRDRFGGRIRFFISGSAALNTDIAQWFNGAGLTILEGYGMTETSSAATVNRPYAQRTGTVGWPLIGTEVRIAEDGEVLMRGPGVMQGYHDNPEATAETLDADGWLHSGDIGEIDERGFVRITDRKKDLFKTSNGKYVAPSQVESTFKGLCPYVGQLLVHGEGRHFVTALVTLDEEAIKPWAQANGLGDASYEEIVSSAQARDMVQGYVDELNSGLNKWERIGKFTILGRDLSVEEGELTPSLKLRRRVVADKFKGDIDGMYAG
>NZ_CP044548.2|WP_083968753.1|1247611_1247956_-|YlxR-family-protein
MPDAAGGRARLEETDRTGLRAPAAPSGPLRTCIGCRGTDSRSILLRVVAETHPDGLTVLVPDPRRRAPGRGAWLHPDLRCFDLAVRRRAFARALRCSPGGIDDLRSWVADHAQR
>NZ_CP044548.2|WP_123092806.1|1247948_1249007_-|transcription-termination/antitermination-protein-NusA
MDIDIHALRAVERERDIPFDVLVEAIEAALLGAYHHTPGAYKHARVELDRKHGHVVVWAREETVVEEPAPEGEVGEDGEPVRPRLRREVGPEFEHTPSDFGRVAAATARQVIVQRMRDVEDEAVLGDFRGREGDIVAGVIQQSPNPRHVTVDFGTVEGILPLAEQVPGERYVHGERIRTYVVSVRRGMRGPEIGLSRTHPNLVRKLFALEVPEIADGSVEIAALAREAGHRTKIAVRSKVPGLNAKGACIGPMGQRVRAVMDHLQGEKIDIVDYSERPQDFIAAALSPAKVQSVEVVDPTLRSARVIVPDYQLSLAIGKEGQNARLAAKLTGWRIDIRPDTAPSGAPEAGRA
>NZ_CP044548.2|WP_123092805.1|1249014_1249569_-|ribosome-maturation-factor-RimP
MSLEHDLRELVAPALGADVVVDDVTVTPAGRRRVVRVTVDRALDGLGGTDPVEPLSLDEVADATRAVSDVLDASDALGSQPYTLEVSTPGVSRPLTTPEHLRRNLGRLVEVERTDGGPVTGRVLEVTPSTLRLQIPAERKTPASEVEIPLPDITRGRVQVEFSRPDADETESPSDQPEQPDESR
>NZ_CP044548.2|WP_123092804.1|1249701_1250559_+|hypothetical-protein
MPVTPSPSRRALLLGTVAAVSLGGCGVRLEDDAPDIPILPRRTPVPGEVPLLALLSSLSHESADDSVPQGSAPARAQVLRASLVELEVPARELDDAEARVPTWGEGEDVAVYESALRECPPGLVQQVGSMAVGRVLRGPARLWGRDSAAAWSSTDAAVSAAADTRAATWVLTVAAAKASGAEQTRITDLVDDLEDLLARQVSAGEDDGSRAPLGYDLEASTRTPQARRELAATVLDRMAGRLVALLPDLAEDRDAAHEVVTWAARVYRLGRPWGVTVDELPGFGS
>NZ_CP044548.2|WP_123092891.1|1250555_1251464_+|phosphotransferase
MSRVELPPALVEGVRGLEPDGGPSGADWVDALPALLTAVLEDWGLVPDGPARHGRTALVVPVAGADLPRGGAALKLVWPHAEAATEHLALRRWDGDGAVGLLRADPSRGALLLERLRDEDLTQMWDEQACEVVAELYGRLHVAPYPQAPRLSTWLAHQSEALAASGDVLPRRLVARARSLMTQIAQDPACDATLVHTDLHFENVLSDGTDWVAIDPKPMAGHPAFEIAPMLGNRTDEMGTGSSLRYLVRRRAEVLCERSGIAWEQARDHTVVRECVTAMWATQAGDRDRVSLAMSLVKALED
>NZ_CP044548.2|WP_163562386.1|1251639_1252239_-|histidine-phosphatase-family-protein
MSPTHVHLVRHGESTWNRDGRVQGAYCGADQAELTATGRADAARAGLTLGSRIGVPRGERSLWLWSSDLRRALETAQVLAVALRPSGWTASVRHEPGLREQSLGDLEGREARTLRAEPVPEGEHVSEVRWGGGESMHDVFERVGAWLAPALLEQREHLVVISHEHTIRAALAWLRSTSHRDVDWDEPVPPGSVTTHEVR
>NZ_CP044548.2|WP_123092802.1|1252277_1253762_+|cobyric-acid-synthase
MSGLLVTGTSSDAGKSLVVTGLCRVLARRGLSVAPYKAQNMSNHSMVCRDGSEIGRAQHLQAQAAGVEATSAMNPVLLKPGSDRRAHVVVRGRPAGELRAGEYATGRAHLAQAAFAAFEELAQTYDVVVCEGAGSPAEINLRAGDYVNLGLAQRFGLPTVLVGDIDRGGVLAALYGTWALVSDDDRPLLAAYLINKFRGDASVLQPGLEEITRRTGMPSLGVLPWLHDVWLDSEDSLSMGAWGDADDGVPDDARLSVAVVRLPRTSNGTDVDALAAEPGVDVRVTVDADLAREADLLVLPGSRATTSDLAWLRRTGLADVVRDRAARGAPVLGICGGYQMLLDEIVDDGVEGDGTGGEGGAPTGSVAGLGLLPGRVVFFEDKVLARPTGRWRGHDVEGYEIHHGVVTPEGGEDFPGGHAVGPVIGTIWHGTLECDDFRRELLREVATTTGSRWAPQAGASPFAARREQMIDVLADAIETHVDVDAVLALAQETR
>NZ_CP044548.2|WP_123092801.1|1253758_1254556_+|precorrin-6A-synthase-(deacetylating)
MSTRRIHVIGIGAGSPEHVTAEAAAALAEVDVFLVADKGETKDELVALRRSICERFVPADHPYEVVAVPDPQRGPDAARDGAQYAKGVADWHAARTEAYVRVVEGLPPEAVVGFLVWGDPAFYDSTIRVVDAIGERLATTVRVIPGISAFQALAAAHGVVLHRVGEPVHITTGRRLVHDWTRAGEAGLDLGTVVVMLDGHLRCRELVATAPATTIHWGAYVGMPQQELRSGRLDEVIDDVVELRARLREEHGWVMDVYALTPSRS
>NZ_CP044548.2|WP_123092889.1|1254611_1256252_-|5,6-dimethylbenzimidazole-synthase
MGEDVTEALAAVVTGRRDIRRFRPDLVPEELLTAVLEAGHRAPSVGHSQPWRFVVVTDPATRDRAAAMADRCRAQQAAHLSSERAARMLDLKLEGLREAPVGVVVACDRRVPAGGVLGRATYPDADLWSCATAVENMWLTARAHGLGMGWVTLFEPDELADLLALPDGVVTLGWLCLGWPDERPPSPGLERAAWSRRAPLEEVVVRERWPADEGGPARPVSHLRGPQPERLVGATDAADELLSPPESLGVLDRALSRVLAVGAGDVVGGTLVLAGADHPVTSLGVSAYPSETTHDVLSATVAGSSLGAATAAGAGLAVVAVDAGVAAPVRGAHDARPAGVRGDLATADAMSDTDVADLLAAGREIGRSAGSRGLVCLGEVGVGNTTVAAALACALLDLEPQDAVGLGSGSDAAMVARKREVVASALARTAWERDPLRLLAALGGPEIALLTGVTLGAAAAGAPVVLDGLAGSLPGLVASRLEPAAQAYLLAGHVSRERAHALVLRELGLEPLLALRLRSGEGVGACLAASLVLQGLAVRRVAARTR
>NZ_CP044548.2|WP_123092800.1|1256389_1260100_-|cobaltochelatase-subunit-CobN
MTTLALLSTSDTDLLSAREAARTHGIDVVLANPARPGHTDMGELIASADVVVARILGTPDDLCSGFRRLAEQGARLVVVGGTQEPDAALMEMSTVPAGVVAEAHRYLAEGGPDNVAQLHAFLGDTLLLTGEGFEAPKALPQWGVLERPEPEPLPDGAVRPRVGVLIYRAQYAAGNTAYAHALADAIDAAGGHGVVVHSASLRDAPDGLLEHLGTLDALVTTVLAAGGTKPATASAGEDDEAWDVERLAALDIPILQGLCLTWSRADWQASDDGMSPLDVATQVAVPEFDGRLITVAFSFKEIDDEGLPHYVADPERAARVAGIAVNHARLRSTPVAERKIAVVLSAYPTKHSRLGNAVGLDTPVSTIRLLRLMREAGYDLGEGFVGMDPLPEVEGEAPDTTSGNALIHELIAAGGQDEEWLTQEQVEGAQVRIPAERYRGWFDALPADLREAMTQHWGDAPGEVFVDTTRDAKGEIVTAAIVRGNVALLVQPPRGFGENPIAIYHDPDLPPTHHYLATYRWVEEEFGAHAVVHVGKHGNLEWLSGKNLAMSASCGTDAALGSLPLVYPFLVNDPGEGTQAKRRAHATIVDHLVPPMARAESYGDIARLEQLLDEYGNVSVMDPAKAPALRGEIWQLIHAAQMHVDLGLEDVDLDDADGFDELVMHVDGWLCEIKDVQIRDGLHVLGQAPQGDELVNLVLAVLRAAQVFSGQVGSVPGLRAALGLAEDAGTVETDAVEGRARRLVEGLAAADWRADAAAGVATRCEPDLGDDAAAGVVAVLEFAATQVVPRLAGTERELAMVLHALDGGYVPAGPSGSPLRGLINVLPTGRNFYSVDPKAIPSRLAYQTGTAMADSLLARYLEDTGELPRSVGLSMWGTSAMRTSGDDIGEVLALLGVTPVWDEQSRRVTGLAPIPLEELGRPRVDVTVRISGFFRDAFPHVIALIDDAVALVAGLDESEEDNHVRAHAAADLADHGDERRARTRIFGSKPGSYGAGILQVVESGTWRSDDDLAQVYTAWGGYAYGRDLDGAPAAEDMERTYRRIQVAAKNVDNRESDILDSDDYFQYHGGMVATVRALTGAEPKAYVGDSTSPDAVRTRTLQEETNRVFRSRVVNPRWISAMQRHGYKGAFELAATVDYLFGFDATAGVVHDWMYDRIAKDYVLDETTQDFMRRANPWALRGIVEKLTEAVERGLWQEPDPEVITQMQQVYLDVEGDLEDDADDVVGVGGAVDARA

Crispr_ID: NZ_CP044548_8

• CRISPR_ID: NZ_CP044548_8
• CRISPR_location: 1357889-1357962
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_8

Consensus_repeat	Method
CTGCGACGAGCCTCGAGACCACC	CRISPRCasFinder

spacers of NZ_CP044548_8

>8.1|1357912|28|NZ_CP044548|CRISPRCasFinder
CACTTCGCTGGTCGAGGTGCGAGGAGCT

CRISPR arrays and Neighbor proteins around NZ_CP044548_8

CRISPR arrays

The CRISPR arrays of NZ_CP044548_8

>merge|NZ_CP044548|8|1357889-1357962|CRISPRCasFinder
CTGCGACGAGCCTCGAGACCACCCACTTCGCTGGTCGAGGTGCGAGGAGCTCTGCGACGAGCCTCGAGACCACC

>NZ_CP044548|8|8|1357889-1357962|CRISPRCasFinder
CTGCGACGAGCCTCGAGACCACC	CACTTCGCTGGTCGAGGTGCGAGGAGCT
CTGCGACGAGCCTCGAGACCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123093278.1|1357446_1357827_+|DUF393-domain-containing-protein	unknown	unknown	gnl|CDD|367833
NZ_CP044548.2|WP_123093275.1|1351403_1353002_-|signal-recognition-particle-protein	unknown	unknown	gnl|CDD|236780
NZ_CP044548.2|WP_123093336.1|1350606_1351398_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|182637
NZ_CP044548.2|WP_068274583.1|1370527_1370812_-|acylphosphatase	unknown	unknown	gnl|CDD|237712
NZ_CP044548.2|WP_123093286.1|1370810_1372811_+|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_CP044548.2|WP_123093273.1|1348143_1349226_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|238624
NZ_CP044548.2|WP_123093280.1|1358869_1360456_-|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl|CDD|236686
NZ_CP044548.2|WP_123093271.1|1346429_1346888_-|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224870
NZ_CP044548.2|WP_068274613.1|1355481_1355820_-|P-II-family-nitrogen-regulator	unknown	unknown	gnl|CDD|198006
NZ_CP044548.2|WP_123093285.1|1370140_1370473_-|chorismate-mutase	unknown	unknown	gnl|CDD|181719
NZ_CP044548.2|WP_123093281.1|1360485_1364028_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP044548.2|WP_163562388.1|1358064_1358793_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP044548.2|WP_123093287.1|1372845_1373721_-|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	unknown	unknown	gnl|CDD|234899
NZ_CP044548.2|WP_123093272.1|1347094_1348021_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP044548.2|WP_123093274.1|1349234_1350533_-|M18-family-aminopeptidase	unknown	unknown	gnl|CDD|235073
NZ_CP044548.2|WP_123093276.1|1353026_1355411_-|[protein-PII]-uridylyltransferase	unknown	unknown	gnl|CDD|235123
NZ_CP044548.2|WP_123093277.1|1355816_1357259_-|ammonium-transporter	unknown	unknown	gnl|CDD|223083
NZ_CP044548.2|WP_123093282.1|1364142_1366098_-|M13-family-peptidase	unknown	unknown	gnl|CDD|341056
NZ_CP044548.2|WP_123093283.1|1366170_1366383_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123093284.1|1366471_1370038_-|chromosome-segregation-protein-SMC	unknown	unknown	gnl|CDD|274008

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123093278.1|1357446_1357827_+|DUF393-domain-containing-protein	gnl|CDD|367833	pfam04134, DUF393, Protein of unknown function, DUF393. Members of this family have two highly conserved cysteine residues near their N-terminus. The function of these proteins is unknown.	5.3186e-16
NZ_CP044548.2|WP_123093275.1|1351403_1353002_-|signal-recognition-particle-protein	gnl|CDD|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP044548.2|WP_123093336.1|1350606_1351398_-|alpha/beta-fold-hydrolase	gnl|CDD|182637	PRK10673, PRK10673, esterase.	3.99639e-42
NZ_CP044548.2|WP_068274583.1|1370527_1370812_-|acylphosphatase	gnl|CDD|237712	PRK14422, PRK14422, acylphosphatase; Provisional.	1.83635e-31
NZ_CP044548.2|WP_123093286.1|1370810_1372811_+|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	2.29053e-64
NZ_CP044548.2|WP_123093273.1|1348143_1349226_-|amidohydrolase-family-protein	gnl|CDD|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	8.63441e-59
NZ_CP044548.2|WP_123093280.1|1358869_1360456_-|signal-recognition-particle-docking-protein-FtsY	gnl|CDD|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	3.7462e-147
NZ_CP044548.2|WP_123093271.1|1346429_1346888_-|Rrf2-family-transcriptional-regulator	gnl|CDD|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	1.12149e-38
NZ_CP044548.2|WP_068274613.1|1355481_1355820_-|P-II-family-nitrogen-regulator	gnl|CDD|198006	smart00938, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	4.22818e-47
NZ_CP044548.2|WP_123093285.1|1370140_1370473_-|chorismate-mutase	gnl|CDD|181719	PRK09239, PRK09239, chorismate mutase; Provisional.	1.70087e-50
NZ_CP044548.2|WP_123093281.1|1360485_1364028_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.68277e-92
NZ_CP044548.2|WP_163562388.1|1358064_1358793_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.35638e-05
NZ_CP044548.2|WP_123093287.1|1372845_1373721_-|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	gnl|CDD|234899	PRK01103, PRK01103, bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase.	1.12439e-137
NZ_CP044548.2|WP_123093272.1|1347094_1348021_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.33095e-31
NZ_CP044548.2|WP_123093274.1|1349234_1350533_-|M18-family-aminopeptidase	gnl|CDD|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_CP044548.2|WP_123093276.1|1353026_1355411_-|[protein-PII]-uridylyltransferase	gnl|CDD|235123	PRK03381, PRK03381, PII uridylyl-transferase; Provisional.	0
NZ_CP044548.2|WP_123093277.1|1355816_1357259_-|ammonium-transporter	gnl|CDD|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	4.71687e-147
NZ_CP044548.2|WP_123093282.1|1364142_1366098_-|M13-family-peptidase	gnl|CDD|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0
NZ_CP044548.2|WP_123093284.1|1366471_1370038_-|chromosome-segregation-protein-SMC	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0

Protein sequences

>NZ_CP044548.2|WP_123093278.1|1357446_1357827_+|DUF393-domain-containing-protein
MTPVLVYDGDCGMCTRAASLVSRRLRPSADTYDVEPSQALDLEALGLTTHQCEEALQWVGADGQVSSAQDAVARMLLASRSVVRPAGAALLLPGVNPLAGVVYRWVARNRHLFPGGTAACQLPPTP
>NZ_CP044548.2|WP_123093277.1|1355816_1357259_-|ammonium-transporter
MSPALMPLAAEPPAIDPAATAFMIICAALVLLMTPGLALFYGGMTRAKSVLNMMMMSFGAMGVAGVVYVLWGYSMSFGGADVAGIFANPFDKFGLRGVASTVEGVTTTVGADGMPVIDVFGAGVWLPEVLFAGFQLTFAIITVALISGAIADRVKFSTWMVFVAIWLTLVYFPIAHMVWGGGLLSGAEGGIAGAMYGITDGVANVAPIDFAGGTVVHINAGIAGLVLALVVGKRLGFGKTAMRPHNVPLVMIGAGLLWFGWFGFNAGSELAADGLASLVWVNTTAATAAAILGWLLVEKIRDGHATSIGAASGVVAGLVAITPACGSLSPVGSLVLGAVAGGLAALAVGLKYRFGYDDSLDVVGVHLVAGLWGTVGAGLLATETGLFYGGGIDQTVVQVVIALASLVISAVLTLVIALALKATMGWRVSEDDEVAGIDAAEHAESGYDLVARGGRLGVSSAGVQHDARHHEEVTTEGAKA
>NZ_CP044548.2|WP_068274613.1|1355481_1355820_-|P-II-family-nitrogen-regulator
MKLVTAIIKPHQLDEVKEALEAYGITGMTVSEASGYGRQRGHSEVYRGAEYTVDFVPKIRLEVLVEDMDATSAVDVVVSTSRTGRIGDGKVWVTTVDEVVRVRTGERGVEAL
>NZ_CP044548.2|WP_123093276.1|1353026_1355411_-|[protein-PII]-uridylyltransferase
MTSTSTDPSAPQDLRAARLDLAGTRDFAVPGAGGTRRAAIAAATDRWLTGVFDEAVGARPGLALAAVGSLGRADSGPLSDLDLVLLHDGRSHREREVAVLADRIWYPVWDAGLRLDHSVRTAGECRSVAADDLTAAVGLLDLRLVAGDADLVSGVRSSVAHDWRANARKRLPQLVEATAARHLRHGELAQSQEPDLKESRGGLRDITVLRALTQAWLTDRDRGRLDQAHARLLDVRDAVHLTTGRGRDRLLRDDADAVAALLGLSDSDELLTVVSTSARTIAYALDGATRRAGQSQRARTLRVGPRRPAMVPLGYGLFRHDGEAVLGSTQQVGVDAELPLRAAVVAARNRLPLAPQTLANLSRAPRLSTPWPDGAVRQLTELLASGAGLVPTWEGLDQAGLVSQWLPEWDAVRSRPQRNAVHRHTVDRHILEAVAQAARLSRDVQRPDLLLLGALMHDIGKIAGANDHSVEGAKIARGAMQRLSLPPQDVALVELLVREHLTLIEVATRRDLDEPATIDAVVEVVDGRLETFELLRALTVADSQATGPKAWTQWRADLLGTLTDRVRERLSGSPVAPPQEQGAVDLPPEARDAIGVGHPFVTVTQAPTGWVVHVYDRDRHGLFADTAGVLAAQGLTVRSARLATQDGIAVDQWVVESPGGDAPEPRRLAASLTRLAGGDRGALGALARSRSTRPAFPSAAGATRAFVLPSGSAAASVLEVRTQDRPGLLHDLGMCLAQQGVGVRSAHIATHAGQTLDTFYVTLPGGGPLSPAKTAQVLSALIDACDLDDRPVGG
>NZ_CP044548.2|WP_123093275.1|1351403_1353002_-|signal-recognition-particle-protein
MFTSLSDRLTGTFANLRGKGRLSESDVNKTIRDIRMALIDADVALPVVKEFTSAVRERATGAEVSGALNPAQQVIKIVNEELVGILGGNTRELTLAKRPPTVIMLAGLQGSGKTTFAGKLGARLKEQGHTPILVAADLQRPNAVTQLEVVAERAGVSVFAPERGNIGGHDAGAAGEGTRSFGDPVSVAREGIAHAQSRQHDVVIVDTAGRLAVDADLMQQAADIRTAISPDEVLFVIDAMIGQAAVETAQAFQQGVDFTGVVLSKLDGDARGGAALSVARTTGRPIMFASTGEGVRDLEVFHPDRMASRILDMGDVLTLIEQAERAFDAGQAEEMQRKFLAAEDFTFDDFLQQMAALKKMGSLKSMLKMMPGMGQMAAQLDNLDEREFDRVEAMVRSMTPFERNHPKQINGSRRARIARGSGVQVSEVNQLLERFGEAQKMMKQLARGGGMPGMPGLPGMGGGKKARQPKQVKKKGKSGNPAKRAEQERAAADRAAGKGPAGSAFGAGGGPGAAPDLDPSQLPKGFEKFLGQ
>NZ_CP044548.2|WP_123093336.1|1350606_1351398_-|alpha/beta-fold-hydrolase
MASPVLHHVSKGEHGPRVAFFHGLFGQGRNWGTIAKAIGDIARPTLVDMPDHGRSGWTEQFDYVRAADTVAQTLLSIADDEPWVVVGHSMGGKIAMLLALRHPELVERLCVVDVSPVAYREGREFEGFVAAMRAMDLRSTASREEADAALVEAAPDPGVRAFLLQNLRREGQGWRWQMNLEVLGDAIPALRGWPAEAVEGRTYDGSVLWVAGAESAYVRDEMGPAMRGYFPRTRLLTIKSAGHWVHSEQPEIFVQALRRFLTA
>NZ_CP044548.2|WP_123093274.1|1349234_1350533_-|M18-family-aminopeptidase
MHLDRTAHAEDLADFVEASPSSHHAAAEVARRLQESGFTALVESEAWPSAAGRYLVVRDGAVIAWVVPASATATTPVRVFGAHSDSPGLVLKPQPSTGAHGWLQAGVEVYGGPLLNSWLDRELRLAGRLVLDDGSSVLADSGPLLRLPQLAIHLDRDVNEGLALDRQRQTQPVWGLGAAASADLVGEIASTSGVDAARVRGFDLVTADAARGRIFGQDDVFFASGRLDDLASVHAGVVALGEVAGADADHVAVLAVFDHEEVGSASRSGAAGPFLEDVLARIGIALGASPEERLRAMASSWCVSSDVGHSVHPNYPEKHDPVVRPVLGSGPILKVNANQRYTTDGAGTAAWRGWCAQAGVTSQTFVSNNSVPCGSTIGPITATRLGIRTLDVGIPLLSMHSARELAGTSDLVDLTLAAAAFLGGDGRSSAAR
>NZ_CP044548.2|WP_123093273.1|1348143_1349226_-|amidohydrolase-family-protein
MTTLHVTGRVLLDEHEVVDELWVVGGRITFTAPTTSGPWEHVEGWVVPGFVDAHCHVGLDRHGAVDEATTEQQALADRDAGTLLIRDAGSAADTRWVDERDDLPKIIRAGRHIARTRRYIRNYAWEVEPEQLVSRVRAEARAGDGWVKLVGDWIDREVGDLTPCWPVDVLTEAIAAAHEEGARVTAHCFGEQSLHDFAAAGTDCIEHATGLDDESIATFARQGITVVPTLVNIETFPAIAEPAREKFPDYHRHMLDLHRRRLQTVASAHEAGIPVMVGTDAGGSIAHGLAAQEMHLLTQAGMTHTQALSAGTWAARRWLGRPAIAEGEDADLVVLSADPREDVRACATPRHVVLRGATVA
>NZ_CP044548.2|WP_123093272.1|1347094_1348021_+|sulfite-exporter-TauE/SafE-family-protein
MRKLVLLAVVGFLAQLVDGSLGMAYGVTTTTLLLAIGTNPAAASATVHLAEIGTTLFSGASHWRFGNVDWGVVAKIGIPGAVGAFAGATFLSSLDTGTAKPVMSGILLLLGLYVLVRFTVKGLRKDRLGQPLRKRFLGPLGLFAGFVDATGGGGWGPVGTPALLASGRIEPRKTIGSIDTSEFLVALAASLGFLFALGSQGIEWSWVIVLLVGGAIAAPIAAYIVRIVPPRILGSLVGGLIVLTNARTLMGKDGFALDSTVKWVVYGLVWAAWIGAVAWSTKEHRRERAAEQAQGPHEDERERVGSPA
>NZ_CP044548.2|WP_123093271.1|1346429_1346888_-|Rrf2-family-transcriptional-regulator
MDISARSDYAVRALLSLVAAQDGRPVSVEQLSGEQELPRKFLEAIVADLRRAGLVTSRRGAAGGYLLARPADEISVGDVIRAVDGPLAEIRGQRPQDLVYTGSAQRLPVVWVALRAALRDVLDDTSLAAIASGELPALVQDLASRPDAMHNR
>NZ_CP044548.2|WP_163562388.1|1358064_1358793_+|hypothetical-protein
MSIPPPPPGPGAGGPGQRPPGPPPHGGPPTGGPGGYPGPGGYPGQPGGQPSGRRRVPVWAWVVGGITALVLACCVGFAALVALGVASSPVDDETTSVAPQSSTTAPSEDTSSSPEPEPTQEPEPTQEPEPSSTSSTLPSAPSSSVPPTPAGSTANTDSRYTLKPDQLESEVVRGLGGIGLKKSEVDCPSALVLVADKTATCTAPNPVGDGTATITATVEWAQISGTSIRYYLGFELKTKKST
>NZ_CP044548.2|WP_123093280.1|1358869_1360456_-|signal-recognition-particle-docking-protein-FtsY
MGIDTVLEYVLVAVGLLVLLGGLLVGLLRGRGGSDGDLPEQHRPPERPKGTTDHRSGTIVLDRPSDKATGAPEAPQRPTERDTPSGATAPAEPAEATEVTPAAPSAPAPQAPQSTTPAGAAPSEATSAPTTGQDEPDVYERDADVAPITDAPQAPESQAPAAEPEAPVAQAPQAPPAEPAQAPAAEPEAPAAEPARAPAAEPEVHPLDAVEAEPVTPVDTPAPTRDRMRTLRTRLATSNNAIGKTLLALLSSGSLSEEDWEDVEDVLLRADLGIEPTTELVDSLRAHVAIDGTTDPEVAKDWLYADLLQLVDPSMDRGLAASRVDGRPACLLVVGVNGTGKTTTVGKLARVLVANDRDVVLGAADTFRAAAADQLETWGARVGVPVVRSDRDGADPAAVAFDAVRAGAEMEADCVVIDTAGRLHNKVGLMDELGKIKRVVEKQQPVDEVLLVIDATTGQNGLAQAKVFAQAVDVTGVVLTKLDGTAKGGIVVAVQRQLGVPVKLVGLGEGPDDLAPFVPEAFVDAIVG
>NZ_CP044548.2|WP_123093281.1|1360485_1364028_-|ABC-transporter-ATP-binding-protein
MTTLDLVPQGTTAPPTTTPPPRRQVTWTRLRHPLVTISWLALAGYAAGQAAGSVLAGRLAEDPSAVLVSWLALCLVGGAVLDTVGRLVWAYVVDRAEGRLREDLLDAALDQPLSALSDQAVGEVLDRVDDDTHDVGTLVREQVWTALRAVFTAIPMWVVAALTWWPAWVLFPVFAVGAYVVMRPLMAEVASRKVVEEMAWTDHAAALEEGIAGRDDLRTSLGSPFAVQRLARLSADVHARFHEVIRVERSMTLRAMLLLHGLLAAIAVVGIAVASRGGLSVAQLVTLFLVTTSFVSIVGRVAEQLPDLQAGLGAVIRLRQMLAVEPEPRGGLPVPTEQVDLDFADLHFSYREGTFALAGVDLHVPAGQTIALVGRTGSGKSTLASLVSRAVDPEPGTVLLGGVDVLDIDLQELRRAVGVVTQRTEILAGTLAQNVALFADVERERVEQVVAELGLTEWVDGLDDGLDTVLGPGGATLSAGEEQLVAFARLLLREVRVVVLDEATARMDPVTEQRVVAAADRLLRRRTGILVAHRLSTISRADLVAVLDHGRLVQHGPRVALATQEGPFRELLRAASTASPGAPEPVSGEPVGPADAPVVVAPTLEGSRRRVDPPPSRDPGDGPSLTKGIWHALRIRPGWGLLAAGLFLGFSLTGSLGALTGFTWGHTVQALRDGEQVTPWLVACVVAILVGPVLFAVAIGRYPRWWVEVLLRVRMSVLVGQTADRRLDRVPAGEIVARAMDADRYARYADRWVDLVNGMAIVVITAVSARSPLAGLVLLVVLVAAAGASALGRPIAGRSAAYASTTRAQFGRVLVSTLESARTVKLAGQVPDLRRHLRSVDGGRVDAAIREHRVRAVLDGVPMLMVQAGLVVTWAGVLWGWWGLATALLLVGAVGGFDWFGRVAGAVVTEAPGTRAWQQVTSRLAGGADLMDTAPGVDLVTGAAPAPPEVDRVPLRRLSLVGMTAVHEDGTVGVEDVDLSVGAGELVLLLGQVGSGKSSLLRALAGLVDHRGGLHWNGHEVDDPEVFLRPGQVAYVAQVPRVVSGTFADNVQLGYERLFEAPVQAARLGPDVATAGGPHAAVGHRGVRLSGGQVQRLALARALAADTELLLADDVSSALDATTEVELWRSLRERSVTVVGATSKRAALAQADRVVVLADGRVEASGPWAQLEADFGHLAG
>NZ_CP044548.2|WP_123093282.1|1364142_1366098_-|M13-family-peptidase
MTQTPTFDHPLDPTTRPQDDLYGHVNNSWLSSVEIPADKGRYGVFDVLRERSEEDVRAIVEEAAADPGSDPDARLIGGLFSSFMDEEAVEAAGLAPLRPRLDEVDAVDDARSLLVATGRLGRLGVGGLLAPIVATDDGNPDEYVVYLEQSGLGLPDESYYRDEQHAAVLRAYRGHVETLLSLAGTADAGSVADAVLRVEHRLATGHLDRVSNRDAVATYNPMTADELAQAAPSFDWAAWAQAWGMPDGALERAIARQPDYLRSLSAALDEVDVADWRAWLRWHVVLASAPHLGRDLVAAHFDLAGRTLSGIPEQRARWKRGVSLLEGALGDAVGKLYVERHYPPESQAAMDELVEHLVEAFRRSFASLSWMSEETKAEALAKLESFTPKVGAPVRWKDYSALELTGDLLTDVGRANALAADREIGKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFDADADPAVNYGGIGAVIGHEIGHGFDDSGASFDGTGALRDWWTPQDKVAFTALADRLRAQFDGQRSRTAPDRAVNGALTVGENIGDIGGLAIGHAAYRIAVGEEAATSVGDDGLTGDQRFFVSWARVWCGDARREEAERLLAIDPHAPQDLRGNACRNIDAFHEAFEVAEGDGMWLDPADRVLIF
>NZ_CP044548.2|WP_123093283.1|1366170_1366383_-|hypothetical-protein
MTAIVVGLLLCVALSLAVLGVVLVPARREGRDLLTPRGERVVVRVRGGADAAASRTSAAISGATAGRKRD
>NZ_CP044548.2|WP_123093284.1|1366471_1370038_-|chromosome-segregation-protein-SMC
MYVKSLTLKGFKSFASATHLGLEPGITCIVGPNGSGKSNVVDALAWVMGEQGAKSLRGGKMEDVIFAGTAGRAPLGRAEVSMTIDNTDGALPIDYTEVTIRRTMFRGGSSEYAINGTSCRLLDIQELLSDSGIGREMHVIVGQGQLDAVLRATPEERRGFIEEAAGVLKHRKRKERALRKLETMEVNLARVADLTTEIRRQLGPLGRQAEAARKAAVIQTDARDARLRLVADDLVQMTSALEQEVADETAMLRRRAALEEALATARAEIGEQEALAAQAAPLLADASRRFVGLRSVCDRLESTASVAAERVRLLGQDDEHESTSGRDPEQLRRQAAQARADEDALRAEIDQITQRLADATAAREAAEAAHSAEQDRVQRLVRAAADRREGLARLTGQVGARQSKVEAAEAEVGRLEGVITRAEERAAEAEQAFRQLESSIADAEGSEAGLDEAFERASAAQDAAEAEVTRWQEAERAAERDRGAAQARVEALELSLRRKDGAQTLRDAAGQGAPTILGSIAELITVSGGHEASIAAALGSASEALAVGSATDAAAAVRRLREEDAGQVYLVVGSTAGVVDRSTWPDLPASATWAIDVVAAPDEVAPAVAQVLDRVALVGEDEDAIALSEQGVTAVTRAGDVFGPGFVRGGSASAPSLIEVQSALDEARTTVADATSAGERAAFELARARATLEQAREASDAALDALHDSDAQMSAVAEQLGSHGQTARVARAEAERTRTAIAALTTGLESDRAELAALRSRLEQASAEPAADEAEPTTDDRDRLELEASRSRTAETEIRLTLRTTEERARSLHGRAESLEGAARNEIAARERLRARQERRRREANVAAAVQDAARHAATLVAAAVERAAAAQQQAEAARAERDTRLAQMRTALAAQQDELRELTDTVHRDEVARAQQTARIEQLQQRAIEELGIDPEVLMEEYGPHQGVPHVPSPDDDPDAEPPAPRPYVREEQEKRLRAAERGLKALGRVNPLALEEFAALEERHTFLTTQLEDLRQSKKDLLDIVAEVDQRVEQVFAEAFRDTAEQFEGVFGRLFPGGEGRLTLTDPSDMLTTGIEVEARPPGKKVKRLSLLSGGERSLVAVALLVSIFKARPSPFYIMDEVEAALDDTNLGRLITLFEELRDSSQLIVITHQKKTMEVADALYGVSMRGDGITTVVSQRIRDVAS
>NZ_CP044548.2|WP_123093285.1|1370140_1370473_-|chorismate-mutase
MLGVSQTPPELHRLRQSIDNVDAALVHLLAERFKATQRVGVLKAELGLPAADPGREERQIERLRALADDAGLDPHFAEKFLNFIIAEVIRHHEAIAEGAPVAPPEEPDAR
>NZ_CP044548.2|WP_068274583.1|1370527_1370812_-|acylphosphatase
MSARATFFVRGRVQGVGFRWWTRARALELGLVGHARNMDDGRVEVVAEGEPEQLDRLEALLREAPSTTRRPGRVETVVRQDAPAKGDRTGFVER
>NZ_CP044548.2|WP_123093286.1|1370810_1372811_+|acyltransferase
MPRTLAPQAVSARPRCASPGLSQAAHSVPLVGAAIPTTTPAQDTSRPLPDGVLPARTPRGHLAGLDGLRALAIVAVVLFHLDPAWLPGGFLGVDVFFVISGFLITTLLVREREQSGTVDLRGFWTRRARRLLPALLVCVPACILIARTVEADLLVGIRRQALGALTFSTNWLEIAGGSDYFHSTSPQLFMNFWSLAVEEQFYLVWPLATIALLAVRRHLGLSWGAIATAVLGIGVVSAVLMAVRYDPDFVTRVYYGTDTHLVGLMLGAAMAMSWAGPTRAGTTSPTWHRYRRHLLVAAGLVLLALLALADEGSAWTFRLGIPLASLATAVLLLGAVDRPGRLRSTLELAPLRWIGTRSYGIYLWHWPVILVIGQDLPSAAGTGEFVWTRAWAVLVTIAIADLSFRLVETPVRRLGFGGALRALGRSLHWATPRARQVGAGVIVVSGLVLAVVLLTAPDKTSTQATLEENAAQAAAPRASTEDQVDEGNPDFTMPKGSQIDVFGDSMAVGSVHALRYYFPGVQIDAKSNRQWSDGQRAVEQAGDSLRRAVVLAFGTNAGTDERTVRALLDEIGPDRMVVLVNLHADRLSRIEGDNDTLETIAKDYPNVAIADWDAAVAKDPSQLQADGIHPSLSGAHVYSKVIRQAFADLSEKHTGKPVRLKELPMP
>NZ_CP044548.2|WP_123093287.1|1372845_1373721_-|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase
MPELPEVEVVRRGLADHVVDRTVAQVELRGTRVARRHLPGPEDLVRQLTGSRITGAHRRGKYLWLASAPGPLEPPDHGLVVHLGMSGQMLVSTPGTPDPRHLHARLGFADDGPELRFVDQRTFGGLAWSPLRPDGVPEAVGHVALDPFDPAFDDRAVAREIKRRSSGIKRVLLDQRVVSGIGNIYADEALWRARIHGERPASSLTKPAIERLLGHARDVMTQALGEGGTSFDALYVNVNGASGYFDRSLAAYGQEGRPCPRCGTLMRREQFMNRSSTSCPRCQPRPRLPRA

Crispr_ID: NZ_CP044548_9

• CRISPR_ID: NZ_CP044548_9
• CRISPR_location: 1386041-1386125
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_9

Consensus_repeat	Method
TTCCCGCCCAGGGCGGGAAAGCT	CRISPRCasFinder

spacers of NZ_CP044548_9

>9.1|1386064|39|NZ_CP044548|CRISPRCasFinder
CGACCTCGGGCAAGAACATTTCTTTCCCGAGGTCGCATG

CRISPR arrays and Neighbor proteins around NZ_CP044548_9

CRISPR arrays

The CRISPR arrays of NZ_CP044548_9

>merge|NZ_CP044548|9|1386041-1386125|CRISPRCasFinder
TTCCCGCCCAGGGCGGGAAAGCTCGACCTCGGGCAAGAACATTTCTTTCCCGAGGTCGCATGTTCCCGCCCTGGGCGGGAAAGCT

>NZ_CP044548|9|9|1386041-1386125|CRISPRCasFinder
TTCCCGCCCAGGGCGGGAAAGCT	CGACCTCGGGCAAGAACATTTCTTTCCCGAGGTCGCATG
TTCCCGCCCTGGGCGGGAAAGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123093302.1|1395456_1396233_-|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NZ_CP044548.2|WP_123093297.1|1388263_1388935_-|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|259853
NZ_CP044548.2|WP_123093300.1|1392552_1394094_-|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|234953
NZ_CP044548.2|WP_068274529.1|1391270_1392020_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP044548.2|WP_123093337.1|1379543_1381199_-|DAK2-domain-containing-protein	unknown	unknown	gnl|CDD|274671
NZ_CP044548.2|WP_123093298.1|1389106_1389700_-|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|179314
NZ_CP044548.2|WP_123093301.1|1394122_1395376_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|238287
NZ_CP044548.2|WP_123093339.1|1383306_1383720_+|DUF3515-family-protein	unknown	unknown	gnl|CDD|378794
NZ_CP044548.2|WP_123093292.1|1383724_1384852_-|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234993
NZ_CP044548.2|WP_123093293.1|1384910_1386029_+|cystathionine-gamma-synthase	unknown	unknown	gnl|CDD|99738
NZ_CP044548.2|WP_123093338.1|1381882_1382878_-|thiamine-phosphate-kinase	unknown	unknown	gnl|CDD|235583
NZ_CP044548.2|WP_068274554.1|1381422_1381617_+|50S-ribosomal-protein-L28	unknown	unknown	gnl|CDD|234736
NZ_CP044548.2|WP_123093291.1|1377337_1379539_-|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl|CDD|236794
NZ_CP044548.2|WP_068274551.1|1383001_1383235_+|Lrp/AsnC-ligand-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366431
NZ_CP044548.2|WP_123093290.1|1375988_1376549_-|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|376622
NZ_CP044548.2|WP_123093299.1|1389703_1391140_-|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl|CDD|235490
NZ_CP044548.2|WP_068274561.1|1376654_1377230_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl|CDD|223813
NZ_CP044548.2|WP_123093294.1|1386144_1387140_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|234629
NZ_CP044548.2|WP_123093295.1|1387136_1387910_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP044548.2|WP_123093296.1|1387994_1388204_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123093302.1|1395456_1396233_-|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	2.81664e-93
NZ_CP044548.2|WP_123093300.1|1392552_1394094_-|glutamate--tRNA-ligase	gnl|CDD|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP044548.2|WP_068274529.1|1391270_1392020_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	9.54205e-41
NZ_CP044548.2|WP_123093337.1|1379543_1381199_-|DAK2-domain-containing-protein	gnl|CDD|274671	TIGR03599, YloV, DAK2 domain fusion protein YloV. This model describes a protein family that contains an N-terminal DAK2 domain (pfam02734), so named because of similarity to the dihydroxyacetone kinase family family. The GTP-binding protein CgtA (a member of the obg family) is a bacterial GTPase associated with ribosome biogenesis, and it has a characteristic extension (TIGR03595) in certain lineages. This protein family described here was found, by the method of partial phylognetic profiling, to have a phylogenetic distribution strongly correlated to that of TIGR03595. This correlation implies some form of functional coupling.	2.95065e-146
NZ_CP044548.2|WP_123093298.1|1389106_1389700_-|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	2.211e-126
NZ_CP044548.2|WP_123093301.1|1394122_1395376_-|WXG100-family-type-VII-secretion-target	gnl|CDD|238287	cd00519, Lipase_3, Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site. .	4.78278e-09
NZ_CP044548.2|WP_123093339.1|1383306_1383720_+|DUF3515-family-protein	gnl|CDD|378794	pfam12028, DUF3515, Protein of unknown function (DUF3515). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 166 to 214 amino acids in length. This protein has a conserved RCG sequence motif.	6.26313e-06
NZ_CP044548.2|WP_123093292.1|1383724_1384852_-|D-alanine--D-alanine-ligase	gnl|CDD|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	0
NZ_CP044548.2|WP_123093293.1|1384910_1386029_+|cystathionine-gamma-synthase	gnl|CDD|99738	cd00614, CGS_like, CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.	9.23374e-117
NZ_CP044548.2|WP_123093338.1|1381882_1382878_-|thiamine-phosphate-kinase	gnl|CDD|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	4.85813e-88
NZ_CP044548.2|WP_068274554.1|1381422_1381617_+|50S-ribosomal-protein-L28	gnl|CDD|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	3.01945e-24
NZ_CP044548.2|WP_123093291.1|1377337_1379539_-|ATP-dependent-DNA-helicase-RecG	gnl|CDD|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP044548.2|WP_068274551.1|1383001_1383235_+|Lrp/AsnC-ligand-binding-domain-containing-protein	gnl|CDD|366431	pfam01037, AsnC_trans_reg, Lrp/AsnC ligand binding domain. The l-leucine-responsive regulatory protein (Lrp/AsnC) family is a family of similar bacterial transcription regulatory proteins. The family is named after two E. coli proteins involved in regulating amino acid metabolism. This entry corresponds to the usually C-terminal regulatory ligand binding domain. Structurally this domain has a dimeric alpha/beta barrel fold.	4.5108e-10
NZ_CP044548.2|WP_123093290.1|1375988_1376549_-|hemerythrin-domain-containing-protein	gnl|CDD|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	4.08762e-06
NZ_CP044548.2|WP_123093299.1|1389703_1391140_-|3-isopropylmalate-dehydratase-large-subunit	gnl|CDD|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP044548.2|WP_068274561.1|1376654_1377230_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl|CDD|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	2.38907e-64
NZ_CP044548.2|WP_123093294.1|1386144_1387140_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	9.86849e-166
NZ_CP044548.2|WP_123093295.1|1387136_1387910_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.67485e-46
NZ_CP044548.2|WP_123093297.1|1388263_1388935_-|HU-family-DNA-binding-protein	gnl|CDD|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	8.75895e-28

Protein sequences

>NZ_CP044548.2|WP_123093293.1|1384910_1386029_+|cystathionine-gamma-synthase
MTSEQPTGADGHATHAGSPFAPATQVVALGRPDRAPGAPLAVPPVFTSTYAADGPVNYARAGNPTWSALEDSVGPLEGGDALAFASGMAAVAAVLSLVPTGGTVVAPFAAYNGVVVSLTEAQEAGRLAVRWVDVTDAEAVEAALPGADLLWLESPTNPLLDLADVERLAHAGRAAGAVVAVDNTFATPLLQQPLALGADVSVHSATKYLSGHSDVILGMTITGTDERGRALRDRLARHRLLGGAIPGPMEAWLVLRGLRTLAVRLERACENAVELAARLREHPSVTRVRYPGLGAIVSVETVGGAEGAERVCAGTHLWSHSTSLGGVESQLERRRRQPGEPESTPVDLVRLSVGIEDVEDLWRDLDAALRLA
>NZ_CP044548.2|WP_123093292.1|1383724_1384852_-|D-alanine--D-alanine-ligase
MTTHEPRKPRVAVVFGGRSSEHAVSCATAAGVLSAIDRERYDVVPIGVSRDGSWVLVDDDPEPLRLVPGHTPEVVHAGTEVALSTSVGDRTLSVHAPGQPPQAFGEVDVVFPLLHGPYGEDGTLQGMLELADVRYVGSGVLASAAGMDKHYMKVVFAGAGLPVGPYTVITDRQWRADPAAAMDAVGALSWPVFVKPCRAGSSMGVSRVERPEDLEAAIEAAREHDLKVIVEAGIVGREIECAVLEGHGLDAPRTSLPGEIVVESGHGHDFYDFEAKYLDESAVRLSCPAELSEQVSDEVRRLAAEAFDALACEGLARVDCFVTDRGEVVINEINTMPGFTPHSMYPRMWQASGLAYPDLIDELVQLALERPVGLR
>NZ_CP044548.2|WP_123093339.1|1383306_1383720_+|DUF3515-family-protein
MALGVLLTRTGPVDVAIPDGGDDPACLDAGTRWPLEVAGEDERDTDPAGTAVHAWGDPAVIARCGLPALGPTTEQCISVDGVDWVARELSDGTALTTFGRSPAIEVLVPDEVGQAPLVLPAFADAAKALPTNGRQCD
>NZ_CP044548.2|WP_068274551.1|1383001_1383235_+|Lrp/AsnC-ligand-binding-domain-containing-protein
MVQAYVLIQTEVGVSTRVCTDIAELTGVVEAHDVTGPYDVVARVEAETMADLGRLVLAQLQQVPGITRTLTCPIVHV
>NZ_CP044548.2|WP_123093338.1|1381882_1382878_-|thiamine-phosphate-kinase
MRLADLDEEAVLARLLPVLLHDEAPGVPVGPGDDAAVVEAPSGSVVATTDSMVLGVDWRDDWSSPQDVGHKLVVQNVADVAAMGARPTGLLLALSADPATPVEWVLGLAEGVAAAARESATPVLGGDLSGAAAGSVVLAMTVLGDLGGRAPVRRSGARVGDVVAVCGTLGRSGAGLRLYLDAELAAAADRQAPEAAHRLRSSHRRPHCPWQSGAEAARAGASAMLDVSDGLVRDAGRLARASGVSVDLDGAALRAETHGDLLDVLGADAALREVLGGGEEHALLACFADASRLPTTGAPWRVVGRVVERSRAPVLLDGVPHEVAGWDHFAG
>NZ_CP044548.2|WP_068274554.1|1381422_1381617_+|50S-ribosomal-protein-L28
MAANCDVCGKGPSFGHSISHSHRRTKRRWNPNIQRVKALVGDAGKTPKRLNVCTSCLKAGKVKR
>NZ_CP044548.2|WP_123093337.1|1379543_1381199_-|DAK2-domain-containing-protein
MRRWAVVTRAALAARRAEIDALNVFPVPDGDTGTNMYLTLDQALDAVRVDHEARGVLGEVDLPGEAAAMSRAAMLSARGNSGVILSQLIRGISDELSGAGTASADAPLLARALGAAARRARESVVRPQEGTILTVADRAAEAAAAAAADGADLPTLTERTVQATRDALAATPSQLPVLAAAGVVDAGGAGYLLFLEALDRVVRDHTPLDRYEVDDFTMNLDLRRRPEWSTGEGGAVTRPVPAEAGGPAAAEGPAFEVMYLLDSEDEQALHDLRCALDALGDSVVLSGDGTTTKVHVHTDDIGAALQAGLAVAPPREVQVTPLVHAMRPHPRVGLAVVACAAGPGIAALVREVGASVVSSGPGRRASAGELLDAVRETRAGDVILLPNDRDTVLAARACAQAAGQEGQHVHVVESGTAVQGLAALAVYDPGADARHNEMTMTRAAAATRHGAVTTAVKAGLTSGGPCEVGDALGVVAGDIAIVGQDLCAVAAEVVARLAGSGADLVTLVVGEDADDELVAAARAAAEALGHGVEVEVVDGGQPAYPLLVGVE
>NZ_CP044548.2|WP_123093291.1|1377337_1379539_-|ATP-dependent-DNA-helicase-RecG
MTTEDTRLKGLVGSAASKLEKHRGIVTVGDLLDFAPRRYRTTVADLGAPAVGDYLVAVATVESATTRTMKSRRGKMLEAVITDGRSRMDVTFFSAYGHEKELQVGRTLLFAGRVGEYRGRRQLAHPAYSSIEALHALGDLAVDEGGLIPIYRHVPGVQSWGVSAAVRVVLQHLDEVVDAVPDEVRERRDLLGRLEALTALHAPHTLDDVERARHRLRFEEAFVLQCLLGMRRAERAAEVTRARRPDGRLLATFDERLPFELTAGQREVGEAVLADLAADTPMHRLLQGEVGSGKTVVALRAMLAAVDSGGQAALLAPTEVLAVQHERTIRGMLGDLAEAGMLGGAEDATRVQLLTGSMSTQARREALIHIATGAAGIVVGTHALLEDVVTFDDLALVVVDEQHRFGVEQRDALRAKGEHPPHLLVMTATPIPRTVAMTVFGDMATSTLRELPRGRQPVTTHVVPAGNPRWVQRVWERIAEEVAAGRQAFVVCPRIGGDDDVEEGVDLLSEGPVADDEADGERVPDDDAPRPLADVSGTLELLAQVPALAGVSTAALHGRMRPEEKDAVMSAYAAGEIDVLVATTVIEVGVDVPNASTMVVLDADRFGISQLHQLRGRIGRGGHPGVCLLVTGSDAESAQERLQALASTSDGFELARVDLAQRREGDVLGTAQSGVRSQLRHLSLLRDEDLIEAAREDVEVVLAADPDLSAHPELAAAVARWADEERTAYLEKS
>NZ_CP044548.2|WP_068274561.1|1376654_1377230_-|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MTRIISGQAGGRRLRTPAGGGTRPTSDRVREALFSALESRDAVQGAHVMDLYAGSGALGLEAASRGAASVLLVESDRGAIGVIRANIADVGAAGARVQAGTVEAALDRTPTLAYDLVLADPPYDVDEDSLAAVLDLLLTREWLSPDALVVVERSSRSPEPSWPAGLTVEARKDYGETVLWYARTWAADYQI
>NZ_CP044548.2|WP_123093290.1|1375988_1376549_-|hemerythrin-domain-containing-protein
MADHDIARPTSGDIVELIKDDHRRFEELLRELRDTTADRDSARAAFSELLIAHSEAEEEQVYPRLKSKKVIDGEEEEHGEEEHAACNEELLHLLQAKGTDTQKYEDAVEKVATALMHHIGEEELSILNPAATEASEELRQQLGVDWCTHRNRLLEEGCGSLEQVEALVKRDYEQGLLPNDEQPEDE
>NZ_CP044548.2|WP_123093294.1|1386144_1387140_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MSKVAVFGGGSWGTAFATVLADGGNDVSIWARRPELVAQINRGRNEDYLPDHELPQSISATTDPAEAADGAQVVVLSVPSQSLRENLGAWGDVLSQGVVVSLMKGVELGTTKRMSEVISEVGGVPTERIAVVSGPNLAREIVQRQPAATVVACPDQGAADLVAAACATSYFRPYTSTDLVGAEVGGAVKNVIALAVGMAEGMGLGDNTKSSIITRGLAEMTRLGVALGADARTFAGLAGVGDLIATCMSPLSRNHSFGVGLGRGMSVAEVQEHTRQTAEGVKSCSSILDLARAHGVDVPIIEQVSACVHEGISVPDVVHALLSRARKPETD
>NZ_CP044548.2|WP_123093295.1|1387136_1387910_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MAEHRTQVPWMYRLVATVLRPLLRALTPYSVTGLEHVPRSGGFLVTPNHISYLDPFPWAHTLYDEGIAPTFMAKSELFESWWLGPIMRQARQVPVYRERHDAASALRDAVPALEQGRCVAIYPEGTLTRDPDEWPMRGKTGAARLALEARCPVIPIAQWGPQAILPQYAKVPRLLPRRTTHIRFGPPVDLSDLYERDLTTVVVMEATDRIMAAITHEVEQLRGERAPAVRFDPQAHGIATTGDYRHARGRLDSGGAA
>NZ_CP044548.2|WP_123093296.1|1387994_1388204_+|hypothetical-protein
MQATVFSNDADGVVLVTDTGRRLRAPFSAFAGSGLIHVRPGQRLSVELGADDQVSRARVVGIGEGERID
>NZ_CP044548.2|WP_123093297.1|1388263_1388935_-|HU-family-DNA-binding-protein
MNKAELIKSIEASLGSRKAATDALDAVLDAIVREVSKGGKVAITGFGTFEKAARAARTGRNPQTGEPVKIPKTSVPRFKAATSFKGYVANPTSLPKAAPAVARAAAGTVASAVDTAAKVAGLGGGAAARRSSAATSSASKSTGSKSTAPKKTASKSAAAKSAPAKKTAAKSTASKSTASKKTASTSTAKKTTSSMAKKTPAKKTSSGTAKSTPAKKAAKKSAS
>NZ_CP044548.2|WP_123093298.1|1389106_1389700_-|3-isopropylmalate-dehydratase-small-subunit
MEKFTTHTGVGVPLRRSNVDTDQIIPAVYLKRVSRTGFEDGLFAAWRGDETFVLNQPAFAQGSVLVAGADFGTGSSREHAVWALMDYGFRVVISSRFADIFRGNSGKQGLLTAIVSQDDVELLWKYLENEPGAQITVDLTARTVTAGESVYPFEVDAYTRWRLLEGLDDIGLTLSHAEDIDAFEAGRPAFKPTTQPV
>NZ_CP044548.2|WP_123093299.1|1389703_1391140_-|3-isopropylmalate-dehydratase-large-subunit
MGKTLAEKVWDAHVVRRAEGEPDLLYIDLHLLHEVTSPQAFEGLRLAGRGVRRPDLTLATEDHNVPTTPGPITDPVSRTQVETLRSNCEQFGVRLFPMGDAEQGIVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGAIALGIGTSEVEHVLATQTLSLKPFRTMAIEVVGEPAPGVTAKDIILAVIAKIGTGGGQGYVLEYRGPAIEAMSMESRMTVCNMSIEAGARAGLIAPDETTFEYLREREHAPKGQDWDDAVAAWRELRTDDDATFDAVVEIDAASLTPFVTWGTNPGQGAPLGDAVPDPESFGDESDRVAAARALEYMGLTAGTPLRDIAVDTVFVGSCTNGRIEDLRAAAEVVRGRSVADGVRMLVVPGSARVRLQAEAEGLDEVFTAAGAEWRLPGCSMCLGMNPDILAPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLASPADLDPTPVGADGASSARS
>NZ_CP044548.2|WP_068274529.1|1391270_1392020_+|IclR-family-transcriptional-regulator
MDNGSGVGVLDKAAVVLSALEAGPSTLAQLVTATGLARPTAHRLAVALEHHRLVGRDMQGRFILGPRLGELAASAGEDKLLVAAAPVLGALRDHTNESAQLFRRQGEHRVCVSAAERPVGLRDSIPVGATLSMLAGSAAQVLLAWEEPDRLHRGLHGAAFSATMLSQVRRRGWAQSVGEREAGVASVSAPVRSPSGRVIAAVSISGPIERLSRQPGRLHAATVIAGANKLTEVLERHAKAAEVADRDTE
>NZ_CP044548.2|WP_123093300.1|1392552_1394094_-|glutamate--tRNA-ligase
MTEQTPSAPSRPRLRVAPSPTGDPHVGTAYMALFNLAFVRQQEGSFVLRVEDTDRARFDATSEAQLYDTLSWLGLTWDEGPDVGGPYAPYRQSERLDTYRPYVERLIADGHAYHCWCSTERLSAMRERQQKLKQPTGYDRMCVGKTREERAELEGFTETPVVRMLVPEDAPTTFEDVIRGTVSAPRPDDQVILKADGFPTYHLAVVVDDHEMGITHVVRGEEWISSTPKHVLLYRWLGLTPPKFAHMPLLRNENKSKISKRKNPWARLTWFREQGYLPEAVVNFLGLLAYPPAKGEDGTDVEKFTFADFSRDFAWSKVNTVGPIFDLKKLDWLNGQYIRDLDVDDLAGRLLPYLQTAGVLGENPSLGELARLRSITELISTRMALLSEAPALVAPFYVADDELEIAQDARDGLKDDAPAVLDAAITALEGLHVPDGVLSAEAREGNQWHAEQIEAALRAAIVEGMGRKPRLAFGPLRTAVSGQRISPPLFESMEILGQHSTLARLRRLRAELG
>NZ_CP044548.2|WP_123093301.1|1394122_1395376_-|WXG100-family-type-VII-secretion-target
MTLTHGADAAVLREISARLTATARQTTQVGDSGRAQLVTLQGAWEGDDLERFAHRWARARGDLERCSQMLDALAAELQRQAQEQQDASGQVGGGASGSAGGSVAPFGGGRLPQGPTPQSPPGRSTFDDDVRGTEGQPVDRDLWGLAFYAQGTRHPLHGVPVIGYQQPALPEGYTEVSAAELTELGLDPARFGPDSTPQAYVFRTEDGGYVVAFQGSVEGEDWVTNGRQALGAGDPQYTAAMQLGLDVQAATGGEVTFTGHSLGGGLAAAAGLATGQPAVTFDAAGIHPTTAAEAAAMRADGSTGASVLAEAGAGQMRAYSVSTDGLTGLQQATGLPDAPGTQIVLDTPPSPERDVVVGTSAGLGGLVGGLVGLGDGDLTDWQEDVGEGAAVGAGLGEGVWGHTWDPMTDALAERYPD
>NZ_CP044548.2|WP_123093302.1|1395456_1396233_-|fumarylacetoacetate-hydrolase-family-protein
MRIARYTTGDDPVYGLVDGDGTKIAEVSGDPLYQRIELTGRTTTVEEVRLLAPVIPRSKIIGIGRNYADHAAEMGNEVPAEPMMFLVPNTAVVGPGDPVVIPPITKEVSFEGELAVIIGRMCKDIEPEEVKKVIFGYTIANDVTARDLQRGDGQWARAKGLDTFCPLGPWIETDLDPQSVDIVTTLDGEVAQDGHSSDMVHGVAELVSYASKAFTLLPGDVILTGTPAGVGRVVAGQRVEVEIAQIGTLSNPFVAAED

Crispr_ID: NZ_CP044548_10

• CRISPR_ID: NZ_CP044548_10
• CRISPR_location: 1840824-1840930
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_10

Consensus_repeat	Method
GGCACGCCCTCGCACTTGCTCGTCCCCGC	CRISPRCasFinder

spacers of NZ_CP044548_10

>10.1|1840853|49|NZ_CP044548|CRISPRCasFinder
CCAGGGGGACGAACGCGCCTTCCCGCCGACCTGGCCGATCGGACCCTCG

CRISPR arrays and Neighbor proteins around NZ_CP044548_10

CRISPR arrays

The CRISPR arrays of NZ_CP044548_10

>merge|NZ_CP044548|10|1840824-1840930|CRISPRCasFinder
GGCACGCCCTCGCACTTGCTCGTCCCCGCCCAGGGGGACGAACGCGCCTTCCCGCCGACCTGGCCGATCGGACCCTCGGGCACGCCCTCGCCCTTGCTCGTCCCCGC

>NZ_CP044548|10|10|1840824-1840930|CRISPRCasFinder
GGCACGCCCTCGCACTTGCTCGTCCCCGC	CCAGGGGGACGAACGCGCCTTCCCGCCGACCTGGCCGATCGGACCCTCG
GGCACGCCCTCGCCCTTGCTCGTCCCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123092289.1|1843057_1843876_-|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181723
NZ_CP044548.2|WP_123092387.1|1847339_1849343_+|PhoX-family-phosphatase	unknown	unknown	gnl|CDD|225752
NZ_CP044548.2|WP_123092290.1|1844021_1845953_+|2-oxoacid:acceptor-oxidoreductase-subunit-alpha	unknown	unknown	gnl|CDD|274738
NZ_CP044548.2|WP_123092388.1|1850333_1851338_-|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NZ_CP044548.2|WP_123092291.1|1845955_1847107_+|2-oxoacid:ferredoxin-oxidoreductase-subunit-beta	unknown	unknown	gnl|CDD|237006
NZ_CP044548.2|WP_123092287.1|1840132_1840606_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123092385.1|1839011_1839368_-|NAD(P)H-quinone-oxidoreductase-subunit-3	unknown	unknown	gnl|CDD|169084
NZ_CP044548.2|WP_123092285.1|1837868_1838399_-|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|376317
NZ_CP044548.2|WP_123092288.1|1841371_1842994_+|HNH-endonuclease	unknown	unknown	gnl|CDD|238038
NZ_CP044548.2|WP_123092292.1|1851343_1852924_-|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl|CDD|235603
NZ_CP044548.2|WP_123092286.1|1838391_1839012_-|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_CP044548.2|WP_123092389.1|1854554_1856399_-|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl|CDD|235836
NZ_CP044548.2|WP_123092293.1|1852923_1854555_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|235622
NZ_CP044548.2|WP_068276890.1|1849420_1850350_+|EamA-family-transporter-RarD	unknown	unknown	gnl|CDD|225510
NZ_CP044548.2|WP_123092282.1|1835866_1836382_-|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl|CDD|235844
NZ_CP044548.2|WP_123092386.1|1839787_1840105_+|DUF4870-domain-containing-protein	unknown	unknown	gnl|CDD|378240
NZ_CP044548.2|WP_123092281.1|1833807_1835565_-|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl|CDD|223941
NZ_CP044548.2|WP_068276927.1|1835561_1835870_-|NADH-quinone-oxidoreductase-subunit-NuoK	unknown	unknown	gnl|CDD|180218
NZ_CP044548.2|WP_123092283.1|1836374_1836914_-|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|235637
NZ_CP044548.2|WP_123092284.1|1836910_1837876_-|NADH-quinone-oxidoreductase-subunit-NuoH	unknown	unknown	gnl|CDD|376297

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123092289.1|1843057_1843876_-|crotonase/enoyl-CoA-hydratase-family-protein	gnl|CDD|181723	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein.	6.2384e-133
NZ_CP044548.2|WP_123092387.1|1847339_1849343_+|PhoX-family-phosphatase	gnl|CDD|225752	COG3211, PhoX, Predicted phosphatase [General function prediction only].	6.21528e-177
NZ_CP044548.2|WP_123092290.1|1844021_1845953_+|2-oxoacid:acceptor-oxidoreductase-subunit-alpha	gnl|CDD|274738	TIGR03710, OAFO_sf, 2-oxoacid:acceptor oxidoreductase, alpha subunit. This family of proteins contains a C-terminal thiamine diphosphate (TPP) binding domain typical of flavodoxin/ferredoxin oxidoreductases (pfam01855) as well as an N-terminal domain similar to the gamma subunit of the same group of oxidoreductases (pfam01558). The genes represented by this model are always found in association with a neighboring gene for a beta subunit (TIGR02177) which also occurs in a 4-subunit (alpha/beta/gamma/ferredoxin) version of the system. This alpha/gamma plus beta structure was used to define the set of sequences to include in this model. This pair of genes is not consistantly observed in proximity to any electron acceptor genes, but is found next to putative ferredoxins or ferredoxin-domain proteins in Azoarcus sp. EbN1, Bradyrhizobium japonicum USDA 110, Frankia sp. CcI3, Rhodoferax ferrireducens DSM 15236, Rhodopseudomonas palustris BisB5, Os, Sphingomonas wittichii RW1 and Streptomyces clavuligerus. Other potential acceptors are also sporadically observed in close proximity including ferritin-like proteins, reberythrin, peroxiredoxin and a variety of other flavin and iron-sulfur cluster-containing proteins. The phylogenetic distribution of this family encompasses archaea, a number of deeply-branching bacterial clades and only a small number of firmicutes and proteobacteria. The enzyme from Sulfolobus has been characterized with respect to its substrate specificity, which is described as wide, encompassing various 2-oxoacids such as 2-oxoglutarate, 2-oxobutyrate and pyruvate. The enzyme from Hydrogenobacter thermophilus has been shown to have a high specificity towards 2-oxoglutarate and is one of the key enzymes in the reverse TCA cycle in this organism. Furthermore, considering its binding of coenzyme A, it can be reasonably inferred that the product of the reaction is succinyl-CoA. The genes for this enzyme in Prevotella intermedia 17, Persephonella marina EX-H1 and Picrophilus torridus DSM 9790 are in close proximity to a variety of TCA cycle genes. Persephonella marina and P. torridus are believed to encode complete TCA cycles, and none of these contains the lipoate-based 2-oxoglutarate dehydrogenase (E1/E2/E3) system. That system is presumed to be replaced by this one. In fact, the lipoate system is absent in most organisms possessing a member of this family, providing additional circumstantial evidence that many of these enzymes are capable of acting as 2-oxoglutarate dehydrogenases and.	0
NZ_CP044548.2|WP_123092388.1|1850333_1851338_-|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	4.71696e-84
NZ_CP044548.2|WP_123092291.1|1845955_1847107_+|2-oxoacid:ferredoxin-oxidoreductase-subunit-beta	gnl|CDD|237006	PRK11867, PRK11867, 2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed.	2.15381e-173
NZ_CP044548.2|WP_123092385.1|1839011_1839368_-|NAD(P)H-quinone-oxidoreductase-subunit-3	gnl|CDD|169084	PRK07756, PRK07756, NADH-quinone oxidoreductase subunit A.	1.61971e-31
NZ_CP044548.2|WP_123092285.1|1837868_1838399_-|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|376317	pfam00329, Complex1_30kDa, Respiratory-chain NADH dehydrogenase, 30 Kd subunit.	5.75103e-29
NZ_CP044548.2|WP_123092288.1|1841371_1842994_+|HNH-endonuclease	gnl|CDD|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	1.6311e-10
NZ_CP044548.2|WP_123092292.1|1851343_1852924_-|NADH-quinone-oxidoreductase-subunit-NuoN	gnl|CDD|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	3.86606e-159
NZ_CP044548.2|WP_123092286.1|1838391_1839012_-|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	2.03807e-85
NZ_CP044548.2|WP_123092389.1|1854554_1856399_-|NADH-quinone-oxidoreductase-subunit-L	gnl|CDD|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP044548.2|WP_123092293.1|1852923_1854555_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
NZ_CP044548.2|WP_068276890.1|1849420_1850350_+|EamA-family-transporter-RarD	gnl|CDD|225510	COG2962, RarD, Predicted permeases [General function prediction only].	1.29406e-78
NZ_CP044548.2|WP_123092282.1|1835866_1836382_-|NADH-quinone-oxidoreductase-subunit-J	gnl|CDD|235844	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J.	3.4027e-24
NZ_CP044548.2|WP_123092386.1|1839787_1840105_+|DUF4870-domain-containing-protein	gnl|CDD|378240	pfam09685, DUF4870, Domain of unknown function (DUF4870).	2.42952e-19
NZ_CP044548.2|WP_123092281.1|1833807_1835565_-|NADH-quinone-oxidoreductase-subunit-L	gnl|CDD|223941	COG1009, NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion / Inorganic ion transport and metabolism].	1.49384e-87
NZ_CP044548.2|WP_068276927.1|1835561_1835870_-|NADH-quinone-oxidoreductase-subunit-NuoK	gnl|CDD|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	8.6625e-18
NZ_CP044548.2|WP_123092283.1|1836374_1836914_-|4Fe-4S-binding-protein	gnl|CDD|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	7.56955e-31
NZ_CP044548.2|WP_123092284.1|1836910_1837876_-|NADH-quinone-oxidoreductase-subunit-NuoH	gnl|CDD|376297	pfam00146, NADHdh, NADH dehydrogenase.	1.6916e-106

Protein sequences

>NZ_CP044548.2|WP_123092287.1|1840132_1840606_+|hypothetical-protein
MSTSSVERVEGVVVRGHGVASGTGAASPFAAGTIELQAPHLAARGVDLSGFHTATINLDISPFALHLLAPRWTVEGVEWTDVHGAETFSFVECTVTHEGREVAALVYHPHPETKPMHHQPATVVELLAPLLPGLGYGDRLGFAPARGQAELVEGQPA
>NZ_CP044548.2|WP_123092386.1|1839787_1840105_+|DUF4870-domain-containing-protein
MLAHLAPAIAIPLSAGTLGFVASLVVYLMYKDRGDFVRAHAVNSLNVQIVTAIGLILSTLLMVILIGFITYPLICVVAVVIHVIGASKARNGELWSPPLTPAFVR
>NZ_CP044548.2|WP_123092385.1|1839011_1839368_-|NAD(P)H-quinone-oxidoreductase-subunit-3
MEGYVVVAGTLLAGIALVVAAWTARRLLAPSAPTPAKTTTYESGVDPLGDGWTQGQVRYLAYAYLYVIFAVDAVYLFPWALVLRTDLGVASLIEVAIFIGVVLVGLLHAARRGLLRWA
>NZ_CP044548.2|WP_123092286.1|1838391_1839012_-|NADH-quinone-oxidoreductase-subunit-B
MTTDLPMPRPREHEPRVGVVGGHAPRPMKVVLSWGRRYSLWVFNFGLACCAIEFIAASMSRHDFMRLGVIPFAPGPRQADLMVVSGTVTDKMAPAVRRLYDQMPEPKYVISFGACSNSGGPYWDSYSVTKGVDQIVPVDVYVPGCPPRPEALLHGIMRLQERIAAEELSTQGLRRKYAGHRLADAAEVQRGLVSPPAARPGGASDD
>NZ_CP044548.2|WP_123092285.1|1837868_1838399_-|NADH-quinone-oxidoreductase-subunit-C
MTEVRLTAALKEWVRAVGDARDQGYVFFDWLSAVDQHDDAEKPGLDVLCHLLDPTPSPERDQRTLLLRTRVADGAALPSITGVFAGAAWHERETHEMFGVEVEGFDDGSGLGMRPLLLPTGFEGHPLRKSFVLASRATKPWPGGKEPGEGHSTRSPSRRRVQAPGVPGPEWGSEDE
>NZ_CP044548.2|WP_123092284.1|1836910_1837876_-|NADH-quinone-oxidoreductase-subunit-NuoH
MSELEVLARSLGALLAVLVLPLVVGYGEHKVMAHMQGRLGPMYAGGFHGWAQLVADGVKFVQKEDITPAAADRRVFRLAPAVALVPYVLAIALLPMHPAGALAEVPGSVLAVLAVTGVGALGTLMAGWASANKYALIGAMRSAAQLISYELPIVLAVASVAMAAGSLSLSGVVLAWHPAWLLWQVVGAVVFLVAAVAELQRPPFDAPIADSEVVMGPWTEYSGLRFAFFMLAEYAGIVVMSVLFAVLYLGGWRGVGVDAVPALGVLWVLAKAGVVAFVLIWVRVSWPRLREDQLQHLAWARLVPLALLQLAVTAVGVVVTA
>NZ_CP044548.2|WP_123092283.1|1836374_1836914_-|4Fe-4S-binding-protein
MSPKGDRSIVPGLVTGMVTTAKQMLAPVRTAEYPDVAPDLPARSRGVIALVEQNCTSCMLCARECPDWCIYIDSHKETVEAPAGGGRARQRNVLDRFAIDFSLCMYCGICVEVCPFDALLWSPAFEYAEGDIRDLLHEKERLGQWVETAPAPPPLDPGAEPASEVSAASKPARGGRARG
>NZ_CP044548.2|WP_123092282.1|1835866_1836382_-|NADH-quinone-oxidoreductase-subunit-J
MAESALVVLGLVTVLAAVRAVTSARLLRAVLWLVVALLGGAGIYLALGAELVALVQVLVYVGAVVVLFVLALMVTRSPLRPLAEHSGPPARRVVAALAGLGTTGLLLLVLLPLARSWEEGEPRAASSEGIASQVFGTWVWPFELLSLLLLVALVAALAITRERGTSTRGRR
>NZ_CP044548.2|WP_068276927.1|1835561_1835870_-|NADH-quinone-oxidoreductase-subunit-NuoK
MSAQIAVVVASVLAGVGVYGVLARRNAMLVLVALELVLLAAGVLLVTAGAHGPDTTASGNVLTLFVITIAAAEVVLALAVLVAAYRARGHVDLDRPADEDAR
>NZ_CP044548.2|WP_123092281.1|1833807_1835565_-|NADH-quinone-oxidoreductase-subunit-L
MRAALSGREIPLPGAEIGSVSFDPALSLTATTLTIAAVVLLVTLCVQVYSLWYLRDDPRRRSFQSTVTLFGAAMLLLVLSGDLVLSLVGWEVMGWCSYLLVGHDSGRAAARRAAHKAYLVTRAADIALVSGVALLVAGAGTTSLAGITEHWQSTGARLLGAPLVTWALLMVVVGVLGKAAQLPFSDWLPDAMEGPTPASALIHAATMVAAGTVLLAQLAPLLASATGARVLLGLSVSATMVLGALLAALQADVKRLLAWSTVSQVAIMLSPFALVGAGPQDHGAVGAGLAHMYGHALFKALLFLTLGWLATTAGGTAATRLTGAARRHPVALVSWALGLAALAGVPVLVGGVSKEHVVAVALASTRDAGRSGEPAWLPVLVLGALLLTVVLTAAYSARAFVVLAVGRRDEVARTRAVMPPAIVAVLVVLAAGTTLGAIAIWLGAFDPAGHASLLLLLLVTLLVLLGGAAGAWACLDRDPVGDGTGRASRLAAAGLHADRVYVAGVVVPVLALARLVRFVDDAVIGTYVRGAGWLVAGLGGAGEVAHRRSRPGSATLLVALALLLLLGATLVVLLTEPAASPGVLG
>NZ_CP044548.2|WP_123092288.1|1841371_1842994_+|HNH-endonuclease
MFDEIEGLCDKVVSGMQVTTMTAATLAPSQDVAMLTAAAVAVERVRRSADAAQLAILAELARRGFETGPDGSTLETRAPAGEVAELACDTIALALGCSDHDARTRSRLAVRLGDDLDPLIRPLMDGAVTERTLRLVADETQDASRDAAAAVVAHVLAPMRGTDVPRIEALDRHDLAQACRRVLDRTDPGWRESRAEVNRRERTDVRTYPGPLGTTELVACLPSETAHVLMAGVCEIARERQRKDPDLRVGPARALALADLALRGVEVSTHITLGLALVRGPSDPGEAEVAGDVKTAGETRTAGEMRTAGETRTAGDDRTAGETGTASGARAVSAAEGRLIDVGATGKPWVGGVEIPRIGWVPGSVVQQVVERLDSRVTRALLDPETGTVLETSTTGYVPPPSVRRLVELRDTRCRMWGCDRPAVACDLDHATAWPGGPTCGANLSALCRHHHRVKHAPAWSYVLHADGSAEWVSPGGTQRLTWPTAYAPAEAPAQAPAEAASHETTGAPDPSTPTQPTTPDAGAGHEAVGHGAVSTAPPF
>NZ_CP044548.2|WP_123092289.1|1843057_1843876_-|crotonase/enoyl-CoA-hydratase-family-protein
MSETTAPLRVEDDGHVRLWTLDRPDQRNPVTGADMIEAIEAAVDAANDDAQDGSLRVVVLTGAGSAFSSGGDVKAMRRGDPPFGGPVSGSREGYRRGVQRIPTAMARLDVPVVAAVNGPAVGAGCDLALMCDLRVASTSAFFAESFVQLGIVPGDGGAWLLSRLLGPTRASEMVLTGDRVDAQQALDWGLVNAVAEPDELLDVARALAGRVAKNPPSAVRMAKSLLRDAPEVSLRASLETAAAMQAVAHTTQDHREAVDALLERRPGTYTGR
>NZ_CP044548.2|WP_123092290.1|1844021_1845953_+|2-oxoacid:acceptor-oxidoreductase-subunit-alpha
MALGHLRRGLDPDTSGAAAPTMSTKTVETKSQVIIRFAGDSGDGMQLTGDRFTADTALLGNDLSTLPNFPAEIRAPQGTLPGVSSFQLHFADHAVLTPGDAPDVLVAMNPAALKANLRDVPRGATIIVDTDEFSKRNLKKVGYETSPLEDDTLESWHVHAVPLTSITVEALAEHDSLTRKEKERAKNMFALGLLSWMYSRPTKGTEDFLARKFGAKPDILAANLAALKAGWNYGETTEDFAVSYEVAPATAAHGTYRNITGNAALALGLVAASHRAGRPLVLGSYPITPASDILHALSGYKRHGVTTIQAEDEIAGIGIALGASFGGAIGVTTTSGPGVALKAETIGLAVSLELPLVVIDVQRGGPSTGLPTKTEQSDLLQALYGRNGESPVPVIAPQTPADCFDAAVEAVRIATTYRTPVMLLSDGYLANGSEPWRIPDVADLPDLTVELATGPNATDESGEEVFLPYLRDPETLARPWAVPGTPGLEHRIGGIEKADGTGNISYDPDNHDFMVRTRAAKVAGVAATSPQLEVDDPSGEAKVLVLGWGSTYGPCAAAVRQVRDTGTPVAHAHLRHLNPFPANTGDVLRAYDRVVVPEMNLGQLAMLLRAEYLVDVRSHTSVRGLPFTTTELAEVITSAAKEV
>NZ_CP044548.2|WP_123092291.1|1845955_1847107_+|2-oxoacid:ferredoxin-oxidoreductase-subunit-beta
MSIDLGIPTTARGTDGVPALGDDDARQTKRDFTSDQEVRWCPGCGDYAILAAVQGFLPELGLRRENIVFVSGIGCSSRFPYYLDTYGMHSIHGRAPAIATGLATSREDLSVWVVTGDGDALSIGGNHLIHALRRNVNMTILLFNNKIYGLTKGQYSPTSDPGTVTKSSPMGSLDAPFNPVSLALGAEATFVARTMDSDRKHLTSVLKAAAQHRGTSLVEIYQNCPIFNDGAFELIKDRDQQQARLVHLVDGEPVTAGDAEARQVLVRGDSGGVEFVPEGEISAKGWADRVVVHDPAAPDPSQAFAISRLDSTAMTHVPMGIFRDVERPTYDDQVRAQVSSAVEVAGGPADDAALTELLHGHDTWSVLVDPSVTEAEDGDPEES
>NZ_CP044548.2|WP_123092387.1|1847339_1849343_+|PhoX-family-phosphatase
MTCTWKCADACSQPVPNTSENAYFGDVVASSRRSVLRAGALSATAATLVGLAGVAGAQPAAAAPGPGTKGRPHLPRPTSPFGFEGIDPVPAGTDEVVVPQGFQWAPIIAWGDPILAGAPAFDFDRQTSAAQAGQFGYNCDYVGVIPTHRGGKEAVLVANNEYTNNELMFAGYAGASSLTDDQVRITMMAHGMSVVEMRRRDKHSRWTYRKAAPLNRRITVVTPFDIVGPVRGSELVRTSADPRGVRALGTFGNCAGGTTPWDTVLSGEENFNGYFTQPASAGSDRAGQALTRYGLASGSTAQHAWDRVEPRFDLTREPQEANRFGWIIEVDPLDPTSTPKKLTALGRMKHEGANVIISDSGHVVAYMGDDERYDYMYKFVSAKRYRKGDRRHNATLLHQGDLYVATFDGEADGTHDGQGRWVPLTQGGRSAVPGFTHEEVLVYTRLAADAVGATKMDRPEDVEPNLVTGKIYAALTNNSRRTAAEVDGPNPRPSNKHGQVLEITERRGDHTGTRFAWRLVLVCGDPQDPQTYFLGYDKSEVSPISCPDNLAFDGDGNLWISTDGNALGHCDGMYLYPLEGREAGHLQQLLSVPAYSECCGPLIQWDDRVVFAAVQHPGEDTGASTTNVLSTFPYQGNTQPRPAVIMVWPKNRGKGPQHGEGHGHPKR
>NZ_CP044548.2|WP_068276890.1|1849420_1850350_+|EamA-family-transporter-RarD
MTPPSPDQQRSHRLGLLAAWSAYLIWGLFPLYFHALEPSGAWEILAHRIVWTLVVCLGVLLVRGELVGLARLLRSRPRLALAVALAAYVIAVNWGVYVYAVTQGRTHEAALGYFLNPIVTIALGVLVLRETLRPLQWVAVAIGASAGIYLAVVAGTVPWISLVLAASFATYGLIKKRLGASLPALQSLSAETVALAPLAAGVLLWLGLTGVSTFTLDAPLHPALLVLSGVVTAVPLVLFAESARRIPLVTIGLIQFITPVAQLVIGLALLGEHMPSSRWVGFGIVWVALVVLSVDSVLAARRSRVSRRG
>NZ_CP044548.2|WP_123092388.1|1850333_1851338_-|polyprenyl-synthetase-family-protein
MTSSTPGIIAVPGASDDLTARLLDGLERVERVILERTRHEDDFISEANLHLAQAGGKRFRPMLTMLVAELGDGITDEVVAAAAGVELTHLASLYHDDVMDEADMRRGAPSANAKYDNSTAILVGDLLFGSASDIIADLGPQAVKIQAQTFIRLCTGQIRDDRPCPEGEDPQAYYRSVLADKTGVLVATAARYGAMFSGATPEVVAMATEYGERLGVAFQLADDLIDVASLSGESGKTPGTDLREGKRTLPVLHALASDDPADAELQRLLLSDLDDDADLARALELLRAHRAMDLAREETLAVGRGASEVLAPLPDSDAKAALLALAESVVTRAG
>NZ_CP044548.2|WP_123092292.1|1851343_1852924_-|NADH-quinone-oxidoreductase-subunit-NuoN
MPAVLTSLPMAGDFEMADIAYAAVAPMVVVFAGAILGVLVEAFAPRRLRYPLQLGISVVALLGALVALVVPSGDDVTGATVDGTLAIDGPSRYLMGALLVLGLVGLLAMAERFGGDGPDAFTPMGSATPGSQMESAAARAGWATTEVFPLTLFSLAGMMMFTAANDLLSMFIALEVLSLPLYLITGLGRRRRLLSQEAALKYFLLGAFSSAFFLFGAGLLYGYAGSVRLSAIAQAASTSTGEMEGLLLPGVVFLLVGLLFKVGAVPFHSWTPDVYQGAPTAVTGFMAACTKIAAFGALLRLVYVGLETTRWEWHIGVVAIAALTMVVGAVLSVTQTDIKRLLAYSSVAHAGFILVGVLAFDQTAVSGVLFYLVAYGASTIAAFALIAMVRERGAEATHLSQWAGLGRSHPFVAAAMTLMLLAFAGIPLTSGFTAKVAAFVPAVQHGGLSGIVLVVIGVLASAVTAFVYVRIIVLMYFTEPAGEVTLAQPALLSVVAIAVGVVLTVLLGVFPGPLLDLAASSSVFVR
>NZ_CP044548.2|WP_123092293.1|1852923_1854555_-|NADH-quinone-oxidoreductase-subunit-M
MTDLPWLSLLVALPLVGAAVTAALPAALAKRFALGTSLLTLVVGIAAASQFVIGSSEQFQLAEQYSWIPQLGVSWALGVDGISLALILMALVLAPVCMVAAWDDVPGGRSESTYFALLLSLVPFMVGVFAATDVFLFYVFFEAMLIPVYFLIGMYGGERRQYAAVKFLLYSLAGGLIMLVAVIGLYVVGPGGTDGFMIERLTGLDIAQDTERWLFLGFFIAFAIKAPMWPLHTWLPDAAAESRPAVATLLVGVLDKVGTYGMIRFCLQLFPEASQWATPVVVVLALVSIVYGAILAIGQSDMMRLIAFTSVSHFGFIVLGIFAFTSTAHAGSNLYMINHGFSTAALFLVAGMLIARRGSRRIDAYGGWQRVTPALAGVFLVAGLSALSLPGLSTFVSEFLVITGTFQRYPAAGVVASLGLVLSALYVLLMYKRVMTGPAPVVVEGAVTRLEGPDTGGQDLPYVRADLDEGVTPAQIGPVRDLGLREKVVVAPLLAALLVIGFFPKPVLDVLDPAVQRTLQVVGVSDPAHDAPADTASTHGSDH
>NZ_CP044548.2|WP_123092389.1|1854554_1856399_-|NADH-quinone-oxidoreductase-subunit-L
MPLAGAALLLLGGRATDAFGPYLATALSWASFLLGAALLVAMLGVDAGERASHLDLYEWIPAGAFQLSAGMLVDPLSISFVLLITFVGSLIHVYSLGYMEHDPDRRRFFAYLNLFVASMLLLVLADSYLLLFVGWEGVGLASWLLIGFWNHRAAYATAANKAFVANRVGDLGMALAIALMFATFGAVDFASVDSAVGGASTGALTAIGLLLLLGACGKSAQFPLQSWLGDAMAGPTPVSALIHAATMVTAGVYLVVRSHTIFDAAPDAQLVVAIVGAITLVYGAVVGCAKDDIKKALAASTMSQIGYMMLAAGLGPVGYAFAIFHLITHGFFKAGMFLGAGSVMHGMGDQVDMRRFGGLSRAMKITWITFALGWLAILGLPPFSGFWSKDKIIEAAFVGEGWRPWVFGLVALLGAGVTAFYMSRLFFMTFHGKRRWTDDVHPHESPAVMTIPMMVLAVGSAALGGAMVLFDFPTFLEPVFGHHEHEEPVLPIPVLMAATIVLVLAGAALAYLRYVREEVPQVAPRGSVATRAARDDLYQDQLNANFLQWPGIHLTRSLAFTDKAGVDGVFSGLAAAVGGSSSRLRRVQSGYARSYALTMLTGVVVLLGALWVMN

Crispr_ID: NZ_CP044548_11

• CRISPR_ID: NZ_CP044548_11
• CRISPR_location: 2451413-2451520
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_11

Consensus_repeat	Method
GTGGTTTCGAGGCTCCTTCGTCGCACCTC	CRISPRCasFinder

spacers of NZ_CP044548_11

>11.1|2451442|50|NZ_CP044548|CRISPRCasFinder
AACCACCACCGGGTTGCTCTTCGCGCCCCACCCGCCATCACGCGCAGGGT

CRISPR arrays and Neighbor proteins around NZ_CP044548_11

CRISPR arrays

The CRISPR arrays of NZ_CP044548_11

>merge|NZ_CP044548|11|2451413-2451520|CRISPRCasFinder
GTGGTTTCGAGGCTCCTTCGTCGCACCTCAACCACCACCGGGTTGCTCTTCGCGCCCCACCCGCCATCACGCGCAGGGTGTGGTTTCGAGCCTCCTTCGTCGCACCTC

>NZ_CP044548|11|11|2451413-2451520|CRISPRCasFinder
GTGGTTTCGAGGCTCCTTCGTCGCACCTC	AACCACCACCGGGTTGCTCTTCGCGCCCCACCCGCCATCACGCGCAGGGT
GTGGTTTCGAGCCTCCTTCGTCGCACCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_083968415.1|2453196_2454228_-|membrane-protein-insertase-YidC	unknown	unknown	gnl|CDD|234941
NZ_CP044548.2|WP_123093616.1|2448600_2449707_-|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|275105
NZ_CP044548.2|WP_123093611.1|2439401_2439884_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239645
NZ_CP044548.2|WP_123093623.1|2458976_2460077_+|decarboxylating-6-phosphogluconate-dehydrogenase	unknown	unknown	gnl|CDD|236582
NZ_CP044548.2|WP_068270888.1|2454991_2455129_-|50S-ribosomal-protein-L34	unknown	unknown	gnl|CDD|366117
NZ_CP044548.2|WP_123093614.1|2445531_2446173_+|RNA-polymerase-sigma-factor-SigM	unknown	unknown	gnl|CDD|236604
NZ_CP044548.2|WP_123093615.1|2446169_2446985_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123093620.1|2454242_2454605_-|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl|CDD|376620
NZ_CP044548.2|WP_163562441.1|2439856_2441881_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123093624.1|2460078_2461287_+|DNA-replication/repair-protein-RecF	unknown	unknown	gnl|CDD|234608
NZ_CP044548.2|WP_123093621.1|2454601_2454979_-|ribonuclease-P-protein-component	unknown	unknown	gnl|CDD|376392
NZ_CP044548.2|WP_123093619.1|2452534_2453140_-|RNA-binding-protein	unknown	unknown	gnl|CDD|224760
NZ_CP044548.2|WP_068270893.1|2457761_2458895_+|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl|CDD|236089
NZ_CP044548.2|WP_148041629.1|2443590_2445525_+|hypothetical-protein	unknown	unknown	gnl|CDD|270875
NZ_CP044548.2|WP_123093622.1|2455587_2457069_+|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl|CDD|237605
NZ_CP044548.2|WP_123093617.1|2449703_2450825_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|224113
NZ_CP044548.2|WP_068270864.1|2447096_2448122_+|thioredoxin-disulfide-reductase	unknown	unknown	gnl|CDD|273540
NZ_CP044548.2|WP_123093618.1|2451861_2452527_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl|CDD|234637
NZ_CP044548.2|WP_123093612.1|2441877_2443524_+|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl|CDD|240528
NZ_CP044548.2|WP_068270866.1|2448181_2448508_+|thioredoxin	unknown	unknown	gnl|CDD|200072

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_083968415.1|2453196_2454228_-|membrane-protein-insertase-YidC	gnl|CDD|234941	PRK01315, PRK01315, putative inner membrane protein translocase component YidC; Provisional.	2.85265e-140
NZ_CP044548.2|WP_123093616.1|2448600_2449707_-|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.09911e-71
NZ_CP044548.2|WP_123093611.1|2439401_2439884_+|NUDIX-hydrolase	gnl|CDD|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	6.88161e-48
NZ_CP044548.2|WP_123093623.1|2458976_2460077_+|decarboxylating-6-phosphogluconate-dehydrogenase	gnl|CDD|236582	PRK09599, PRK09599, NADP-dependent phosphogluconate dehydrogenase.	2.76402e-178
NZ_CP044548.2|WP_068270888.1|2454991_2455129_-|50S-ribosomal-protein-L34	gnl|CDD|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	1.89813e-09
NZ_CP044548.2|WP_123093614.1|2445531_2446173_+|RNA-polymerase-sigma-factor-SigM	gnl|CDD|236604	PRK09643, PRK09643, RNA polymerase sigma factor SigM; Reviewed.	6.54361e-67
NZ_CP044548.2|WP_123093620.1|2454242_2454605_-|membrane-protein-insertion-efficiency-factor-YidD	gnl|CDD|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	7.80499e-35
NZ_CP044548.2|WP_123093621.1|2454601_2454979_-|ribonuclease-P-protein-component	gnl|CDD|376392	pfam00825, Ribonuclease_P, Ribonuclease P.	3.47717e-25
NZ_CP044548.2|WP_123093624.1|2460078_2461287_+|DNA-replication/repair-protein-RecF	gnl|CDD|234608	PRK00064, recF, recombination protein F; Reviewed.	1.40182e-134
NZ_CP044548.2|WP_123093619.1|2452534_2453140_-|RNA-binding-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	1.64939e-37
NZ_CP044548.2|WP_068270893.1|2457761_2458895_+|DNA-polymerase-III-subunit-beta	gnl|CDD|236089	PRK07761, PRK07761, DNA polymerase III subunit beta; Validated.	0
NZ_CP044548.2|WP_148041629.1|2443590_2445525_+|hypothetical-protein	gnl|CDD|270875	cd13973, PK_MviN-like, Pseudokinase domain of the peptidoglycan biosynthetic protein MviN. The pseudokinase domain shows similarity to protein kinases but lacks crucial residues for catalytic activity. This family is composed of the mycobacterial protein MviN and similar proteins. MviN is an integral membrane protein that is essential for growth and is required for cell wall integrity and peptidogylcan (PG) biosynthesis. It comprises of 14 predicted transmembrane (TM) helices at the N-terminus, followed by an intracellular pseudokinase domain linked through a single TM helix to a carbohydrate binding extracellular domain. Phosphorylation of the MviN pseudokinase domain by the PG-sensitive serine/threonine protein kinase PknB recruits a forkhead associated (FHA) domain protein FhaA, which modulates local PG synthesis at cell poles and the septum. The MviN pseudokinase forms a canonical receptor kinase dimer.	2.2374e-29
NZ_CP044548.2|WP_123093622.1|2455587_2457069_+|chromosomal-replication-initiator-protein-DnaA	gnl|CDD|237605	PRK14086, dnaA, chromosomal replication initiator protein DnaA.	0
NZ_CP044548.2|WP_123093617.1|2449703_2450825_-|AAA-family-ATPase	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	1.36279e-80
NZ_CP044548.2|WP_068270864.1|2447096_2448122_+|thioredoxin-disulfide-reductase	gnl|CDD|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	6.21229e-145
NZ_CP044548.2|WP_123093618.1|2451861_2452527_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl|CDD|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	2.01459e-66
NZ_CP044548.2|WP_123093612.1|2441877_2443524_+|murein-biosynthesis-integral-membrane-protein-MurJ	gnl|CDD|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.56645e-88
NZ_CP044548.2|WP_068270866.1|2448181_2448508_+|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.66648e-49

Protein sequences

>NZ_CP044548.2|WP_123093617.1|2449703_2450825_-|AAA-family-ATPase
MGWPALPAPSESEPIGWQGERVTPRTPDTSAAPSGASPEQAAASPVSRETSMPSDDVGAEDAPKGAAVDDAAEDESPVLAAVNADKRARARLASKTFPTPDRTRVITVSNQKGGVGKTTTAVNLAAALAQNGLTVLLVDTDPQGNASTALNIDHHAEVPSIYDVLIEGTPMADVMQPCPDVDGLWCVPATIDLAGAEIELVSLVARESRMRGALDQLARTRAERGERRIDYVVVDCPPSLGLLTVNAFVAAQEVLIPIQCEYYALEGLSQLLKNIDLIQTHLNPELHVSTILLTMYDGRTNLSRQVAEEVRTHFPDEVIGATIPRSVRVSEAPSFGQTVITYDPQSSGALAYLEAAAEIADRGVGTDGQDGQA
>NZ_CP044548.2|WP_123093616.1|2448600_2449707_-|ParB/RepB/Spo0J-family-partition-protein
MSEKRRGLGRGLGALIPDASTARSRPVDVFFAERDASPAAGAPTDGSSTPNTAAGMLAAAQKAPTGEPTAAHDAPHHVEHPEPAPTQDGLAPVPGAHYAEIPVDAIRPNPRQPRTVFDEDDMAELVHSIREIGVLQPVVVRPLPEGADAQDGVRFELIMGERRWRATRAADRESIPAIVKATEDDDLLRDALLENLHRSELNALEEAAAYQQLLDDFGCTQDELATRIGRSRPQISNTLRLLRLPPLVARRVAAGVLSAGHARALLSLPDGASMERLAQRIVAEGLSVRTVEEIVALGMEPEREARRSSPRLPAPELDDLGAAVSDHLDTRAKISMGAKKGRMTIEFASMDDLTRILERIGMDSTHIV
>NZ_CP044548.2|WP_068270866.1|2448181_2448508_+|thioredoxin
MAGTKPTTDATFEQDVLGSETPVLVDFWAPWCGPCRAVAPVLEELAGQYDGKLSIVKLNTDENPEITSRYGITSIPTMHVYKNGEIVKTLVGAMPKPKLIKELEPFIG
>NZ_CP044548.2|WP_068270864.1|2447096_2448122_+|thioredoxin-disulfide-reductase
MTADVRNVIIIGSGPAGYTAAVYAARANLAPLLFEGAVTAGGALMNTTEVENFPGFTDGIMGPDLMMSMRGQAERFGTEIVTDDVASVRLDGDVKVVTDSEGTEHRAHAVILAMGSAYRELGLPDEKRLSGHGVSWCATCDGFFFRDQDIAVVGGGDSAIEEATFLTKFARSVTIVHRREELRASKIMADRALGNDKIRFAWNSEVSAIHGQDKVSSITLRDTRTGAERDLEVTGLFVAIGHDPRNELLTQTTDAAKVALDAEGYVLAEGRSTRTNLDGVFACGDLVDHTYRQAITAAGSGCSAALDAERWLAEREEAGAPAADQSLISQEDPVEGTVGVR
>NZ_CP044548.2|WP_123093615.1|2446169_2446985_+|hypothetical-protein
MTQDPQRPDEERDDEHVRALLADLPSGDEHPAMPPELVARIEASLHEERRRRRAGATVTPLATHRRRAGSWLLGAAAAVVLVTGTGYVASTTLRGGADSSAGSGAGGSAGDESGPASTRSEDGGLTDGDEGVEDAPSQSAESSTKAFSGNSGRSPFQSSSPFVLTMTERRYTEATLEEGAARTTSVWTRKHRGAVPLSASSPTLGPLTTERGARDCLRQIGAGEVHPVQADVGTFDGRAGFLLVAVGDDGTRAWAVAAGCEPIYDTSVPVR
>NZ_CP044548.2|WP_123093614.1|2445531_2446173_+|RNA-polymerase-sigma-factor-SigM
MRGALDEIDDRELVRRHVAGDPDAFGELFARHRDRMWGVALSVCRDPELAADAVQDGFLAAFRRAEGYRGDAAVTTWLHRVVVNACLDRLRRARPTDSLDELDERASTRLPSRPDGTAQVDTRLLVQDALAALPEPQRLVLVLVDMHGVPVAEAARMLGVAEGTVKSRGSRGRAALAAVLRAGTPDGARTSDDEGGIAPPGRTGPAASAGGEA
>NZ_CP044548.2|WP_148041629.1|2443590_2445525_+|hypothetical-protein
MHEVHPGTTLGRYAIARRAQEPVTGDPSSGQRWVARDSDLERDVVLLVLPLDDPHTDAALDAARRASGVGHPGLTRILDVDHDDERAWVTESFRSDDRSLAELATHGLPAEEVRRITGEVALVLEAARSRGLHHLAISPDSVFVGPDGSVRVRGLAVDAALAGVDEEGDEAAALDGAGVVALAYAGLTGSWPLQTSTSLPAAPRDATGVLPPSHLAVGVPSDLDTICRETLADDAGPSSPGDYAASVSPWSRTPVDDGAAQPLDEAAADDGADAPFADAPGPDDTQVIGVTPAAGAAAQEHRSTAVDSDDDEPTQAISRGATAPSDEPTQVVSAEGSDEPGAARTGRGAAAGAAAVSVAGALAGGGKILGERVGRAAQRTRERAGEAAADRRAQREAIRSSESRDRVSLGSAGSQDDLEPPAPLLPADASEPPSREQSRVVVAIMALFVVVALVVGAVGVSKIGDNTDLSAIFGSDAQGADPVRPTQSSSTSRPSGGGNGARTSEPIPVIGAIGYDPNGDGAEHNSEAQRVYDDDLSTSWTTEGYESPNFGNKGGVGIVLDLGQARQVRSATLQLPQATTVQVFVGDEAGIAGTELGRSEGKNGSVTITGRSAARGQYVTIWFTTTVQSDDGRHRASLAEVVLR
>NZ_CP044548.2|WP_123093612.1|2441877_2443524_+|murein-biosynthesis-integral-membrane-protein-MurJ
MTERAQTPAAAPSVARSSALMASGTLVSRVLGLLRQTMTIGVVGAVGLAADAWNAANTLPNNFHLLLAGGVLNAVIVPQIVKASRRADGDEYVNRLLTLAMTIMGAATVLLTLAAPALVWLVVSKDWGDDARGLAVAFALICLPQMFFYGLYTLLGQVLTANNRFGAFMWAPALANVVAIAGLGWFMLSGRQDVQDVGLWDSTMIWVLAGSATLSIVVQALVLIPALRRIGFRYRPVWGFRGYGLGSASKMATWAFGAVAVGQVAFLLVTTPVLTGAAFDAERAGAPAAGLTSYGFAFLIFMLPHSIITVSLVTAIFTRLSGNAQDGDTEAVAADLRQGMRMPAVVLFPGTAAMVLLAPWALQALLFSTPAADARAATGVLVAMCLGLVPYGWFYLVQRACYAYEDGRTPFVLQLVVTVISVAFTLVGAARGFEHTATWVGVGQTVGNLVGAILGFVLLRRRLGSLGLASVVQQNVRLLLSTLLATLVAGALLLGMTRVLDEGWLSAVLVTGVCGVVLLVVALLVAARLRVTEVTAVLQPVTRRLRRA
>NZ_CP044548.2|WP_163562441.1|2439856_2441881_+|hypothetical-protein
MAAARGRRLRPLRGACVAAALAGLLAPALPARASASDASSSLTLTSITPVVDATGASSGSATIRGRLTNDGSTTLENPAVSVLLGEAEMTREGIDDWAKGDARVTGSALDREIATSRLVPGQSTTFELEVDGADLLPGRSWGAAPISVQSGQDQVHTFLGIHRAKEYEPLKMLWGVPVTLPSSNQLWAAPGDSRTRAWQAAAGPGSDLAQIASSAPRPGDLWLLDPLLLPDAVPADDTGLSRGEREVREDLARDLAAELDPDRTAVLPEADADVAAAAESDAARTLVRPRVTGGQEAAEALGARSDIAWPADDLIAGDRSAALERVYGSQPTVLVPRTALTDTAFTPDAFQTSRGGTPLLVSDPELSAVVGSLREDDDAVLATQRLVADSASVLGDLPGTSRTLLVVPPRSARPDPQAYRAMREAVADIPWTARGTLASPRATAPESPEQEIDIPDTLEDPPEPVLTDARARRVVADIATRRSVATVRADGPQWQRAVAASQVQLTSARWRSSQWHFRVLASRLHRDVTATGRQLEVASGEVNFFADTGRLQITVRNTSDVELHDLQVRLDPGSPILRIDGDPEPITVGPQSRRTVTVQASALAPGRVPIEVEVTDPKGRALAEPAELRVRVSPTGGWIYWGVALVALASVAFGTWRTVRRRPTPAAPADPEDS
>NZ_CP044548.2|WP_123093611.1|2439401_2439884_+|NUDIX-hydrolase
MAHPAHAPRSPRRLPAVEERSAGGVVVDVHEGQARIAVIARRNRAGRLEWCLPKGHIEGEETLVETAAREVAEETGIEARVLVELGTIDYWFATNDRRIHKFVHHYLLEAIGGYLTIDNDPDHEAVDVAWLLLRDAHRHLTFPNERRIAREAWQRLAGDA
>NZ_CP044548.2|WP_123093618.1|2451861_2452527_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MDHAPEATEGAHRFFGERLPRATAFADILADTGVSHGLIGPREVPILWERHILNCAVIEDAFPSGARVVDVGSGAGLPGVATAIARPDLEIHLVEPMMRRTEWLDAVVSDLALENVTVHRARAEEMHGVLSAPFVTARAVARLDKLARWCFPLLDDGGQLVAMKGRSAQEELDAVTPTLRKLGMTAAAVSEHGGEVLPEPTMTVDCTVTPRKPGTKRPRRR
>NZ_CP044548.2|WP_123093619.1|2452534_2453140_-|RNA-binding-protein
MTETTTPETSTEATPEEASTQAPAGTRQSALVREGEVAADFLETLLDICDLDGDIDLDIDGDRAAVAIVDSEDGRVPRRLIGSDGKVLDSLQELTRLAVQSATGERSRLMLDIAGHRAGRRAELVEIARDAVRRSRESGEEISLEPMSAFERKVVHDEVLASGLSSESSGTEPRRYVVVIPEAGTQAEADDEQDASADADA
>NZ_CP044548.2|WP_083968415.1|2453196_2454228_-|membrane-protein-insertase-YidC
MYPFEWLVAWIIVLWHKLLVVIGLPSDNGWTWTLSIVGLVLVMRAALIPLFVKQIHASRKMQLIQPEMQKIQKKYKGKKDPESQQKMQQEMMSLYRETGTNPLASCLPILVQSPFFFGLFRVLNGLDEIASGERQPIGPLTKALAAEAEKSTIFGAQLSDIFLGANTLNVQIVTVVLIILMSATTFTTQHQLMRKNMPTAALEGPFAQQQKIMLYLFPIIFAVSGINFPIGVLIYWFTTNLWTMLQQFYVIRRMPAPGSAAEKAMHERRRKAGKPLDTPEEEREREHDAEMAEELREKGVISGQRVQPKSKKRSKKDGTKKKPGPPPGSSSTATATKNPRNDS
>NZ_CP044548.2|WP_123093620.1|2454242_2454605_-|membrane-protein-insertion-efficiency-factor-YidD
MSGSRAAAPFVLLVRGYQRYLSPLLPARCRYYPTCSAYAVTALRRFGPVRGGYLAVHRIGRCHPWSHGGVDFVPDTWAQRGSPELTRPRLGDDTPALSEADLQTSRRRLGAPRQRRITSP
>NZ_CP044548.2|WP_123093621.1|2454601_2454979_-|ribonuclease-P-protein-component
MLPAQHRLTERGEFTATVRGSGARRQGSRLLVVHARHTDARSALPPRVGVVVSKAVGNAVVRNRVKRRLRAQVAPLLPAVPSGTDLVLRANPASASATSAQIGRTLGSALASLGVTEPSPAEPTP
>NZ_CP044548.2|WP_068270888.1|2454991_2455129_-|50S-ribosomal-protein-L34
MSKRTFQPNNRRRAKTHGFRLRMRTRAGRAILANRRAKGRAKLSA
>NZ_CP044548.2|WP_123093622.1|2455587_2457069_+|chromosomal-replication-initiator-protein-DnaA
MDFAQVWRSTLDSLDADGVPVGRRAFLTHAQLVGLLDSTALIAVPDDFSKEFVEQRLRMQLTQALSAQLGQEVRIAVTVDPDLHQDGEDHLPESSADGSPRDEADVLPLRQGLATQDPLPVGDPMTTRETAAANAGRAGRGTTQPESVELTRLNPKYLFDTFVIGSSNRFAHAAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYARNLYPHVKVRYVNSEEFTNDFINSIRDDKAAAFQARYRDVDVLLIDDIQFLSGKMQTQEEFFHTFNTLHNANKQVVITSDVKPKLLQGFEERMRSRFEWGLLTDVQPPDLETRIAILRKKAIQERLSVPDEVLEFIASRISTNIRELEGALIRVTAFASLNRQPVDLGLAQIVLKDLIPHEAPNEIDAATIMAQTAAYFGLTIEDLQGASRSRVLVTARQIAMYLCRELTDASLPQIGKLFGGRDHTTVMHANRKIGELMAERRAIYNQVTELTNRIKQQANS
>NZ_CP044548.2|WP_068270893.1|2457761_2458895_+|DNA-polymerase-III-subunit-beta
MKFRVERDVLAEAVTWVARGLPARPPVPVLAGVLVSADEGGTVTLSAFDYEVSARITVAADVEESGTVLVLGRLLADISRNLPGRPVDVSTEGTKVQVTCGSSRFALLQMPADEYPTLPTAPEGSGSIDGSVFTQAVAQVSIAADRGDSLPILTGVRVEVDRDRMTLLATDRYRLAMREITWSPRTSDASHVALIPARTLSETARSLGAVGTIDVALGSAAGGDGLVGFEAGQRRTTSRLLDGEYPKVAKIFPTSSETEAVIATADLIEAVKRVALVAERTTPVRLRFSEGQLAIEAGTGEDAQASEALEASVTGPDIAVAFNPGYLLDGLGVLGTEWTRMSFTGALKAAMITGQTSQDGELDTTYRYVLQPVRLAG
>NZ_CP044548.2|WP_123093623.1|2458976_2460077_+|decarboxylating-6-phosphogluconate-dehydrogenase
MQLGLIGLGKMGGNMRERIRRAGHEVVGYDRDQSISDSTSVQDMIDQLEAPRVVWVMVPAGEITRSVVADLAERLDEGDLVIDGGNSRFSDDAVHAEMLKAQGVGYLDCGVSGGIWGLENGYGLMVGGLKKHVTRAMPIFDALRPEGPRDEGFVHAGAVGAGHYVKMVHNGIEYGLMHAYAEGYELLEKKDIVTDVPGAFKAWSRGTVVRSWLLDLMVKALEENPTLDDVSDYTADSGEGRWTVEEAIANSVPMPVISASLFARFASRQDSSPTMQAVAALRGQFGGHQVMTTAEGEQLRAEAATGPKDAKSTQRKAAKKEKPTKDAGTAQAKGRKAASAGPSSGSGSTGGSKGPTSGTRSTRSSS
>NZ_CP044548.2|WP_123093624.1|2460078_2461287_+|DNA-replication/repair-protein-RecF
MHVRHLTVGDFRSYAAADLALEPGITTLVGLNGQGKTNLVEAIGYLATLSSHRVSTDQPLVRVGAERAIIRAAVVRDGREQVVELEINPGRANRAKLGRSPLPRTRDVLGTVRSVLFAPEDLALVKGDPDQRRRFLDDLLVQRQPRWAGVRGDYDKVVRQRSALLKQAGADKRGRGRRARVPEGIDPGAAREEAMRTLDIWDDRLATVGAQLLYARLRLLTDLVPHLTQTYGEVSASVSEATARYRSSIPGPVGEALAEGFESAQDVPPVERLREELLEGMAQVRDQELDRGVSLVGPHRDDITLALGEMPAKGYASHGESWSFALGLRLAAYRLLQHDLDDDPVLVLDDVFAELDSGRRTRLAGLVAGSEQVLITAAVGADVPEELSGARFAVTKGEVSPA

Crispr_ID: NZ_CP044548_12

• CRISPR_ID: NZ_CP044548_12
• CRISPR_location: 2499259-2499343
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP044548_12

Consensus_repeat	Method
TTCCCGCCCTGGGCGGGAAAGCT	CRISPRCasFinder

spacers of NZ_CP044548_12

>12.1|2499282|39|NZ_CP044548|CRISPRCasFinder
CGACCTCGGGAAAGAAATGTTCTTGCCCGAGGTCGAATG

CRISPR arrays and Neighbor proteins around NZ_CP044548_12

CRISPR arrays

The CRISPR arrays of NZ_CP044548_12

>merge|NZ_CP044548|12|2499259-2499343|CRISPRCasFinder
TTCCCGCCCTGGGCGGGAAAGCTCGACCTCGGGAAAGAAATGTTCTTGCCCGAGGTCGAATGTTCCCGCCCTGGGCGGGAAAGCT

>NZ_CP044548|12|12|2499259-2499343|CRISPRCasFinder
TTCCCGCCCTGGGCGGGAAAGCT	CGACCTCGGGAAAGAAATGTTCTTGCCCGAGGTCGAATG
TTCCCGCCCTGGGCGGGAAAGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_123093224.1|2492589_2493411_-|anti-sigma-factor	unknown	unknown	gnl|CDD|378389
NZ_CP044548.2|WP_123093211.1|2507198_2508443_-|Stp1/IreP-family-PP2C-type-Ser/Thr-phosphatase	unknown	unknown	gnl|CDD|223704
NZ_CP044548.2|WP_123093221.1|2494735_2495536_-|DUF4397-domain-containing-protein	unknown	unknown	gnl|CDD|379570
NZ_CP044548.2|WP_123093215.1|2499805_2500594_+|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|377575
NZ_CP044548.2|WP_148041616.1|2491334_2492162_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123093220.1|2495712_2496087_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|377953
NZ_CP044548.2|WP_123093218.1|2497620_2498139_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_CP044548.2|WP_123093214.1|2500613_2501270_+|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|181107
NZ_CP044548.2|WP_123093251.1|2501399_2502362_+|ribonuclease-BN	unknown	unknown	gnl|CDD|377085
NZ_CP044548.2|WP_123093223.1|2493403_2493928_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|237125
NZ_CP044548.2|WP_123093250.1|2509010_2510006_-|DUF3662-domain-containing-protein	unknown	unknown	gnl|CDD|378850
NZ_CP044548.2|WP_123093213.1|2502375_2504307_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP044548.2|WP_163562446.1|2493992_2494700_-|class-F-sortase	unknown	unknown	gnl|CDD|320678
NZ_CP044548.2|WP_123093212.1|2504374_2505829_-|penicillin-binding-protein-2	unknown	unknown	gnl|CDD|274573
NZ_CP044548.2|WP_123093225.1|2492212_2492575_+|tRNA-binding-protein	unknown	unknown	gnl|CDD|182232
NZ_CP044548.2|WP_123093217.1|2498163_2499027_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759
NZ_CP044548.2|WP_123093219.1|2496350_2497475_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_068272308.1|2505825_2507202_-|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl|CDD|223843
NZ_CP044548.2|WP_123093210.1|2508446_2508929_-|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|238017
NZ_CP044548.2|WP_123093216.1|2499356_2499707_-|cell-division-protein-CrgA	unknown	unknown	gnl|CDD|377706

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_123093224.1|2492589_2493411_-|anti-sigma-factor	gnl|CDD|378389	pfam10099, RskA, Anti-sigma-K factor rskA. This domain, formerly known as DUF2337, is the anti-sigma-K factor, RskA. In Mycobacterium tuberculosis the protein positively regulates expression of the antigenic proteins MPB70 and MPB83.	1.1936e-09
NZ_CP044548.2|WP_123093211.1|2507198_2508443_-|Stp1/IreP-family-PP2C-type-Ser/Thr-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.16278e-77
NZ_CP044548.2|WP_123093221.1|2494735_2495536_-|DUF4397-domain-containing-protein	gnl|CDD|379570	pfam14344, DUF4397, Domain of unknown function (DUF4397). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 120 amino acids in length.	7.48865e-27
NZ_CP044548.2|WP_123093215.1|2499805_2500594_+|DUF881-domain-containing-protein	gnl|CDD|377575	pfam05949, DUF881, Bacterial protein of unknown function (DUF881). This family consists of a series of hypothetical bacterial proteins. One of the family members YlxW from Bacillus subtilis is thought to be involved in cell division and sporulation.	1.66105e-51
NZ_CP044548.2|WP_068272308.1|2505825_2507202_-|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl|CDD|223843	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning].	6.23042e-79
NZ_CP044548.2|WP_123093220.1|2495712_2496087_+|PH-domain-containing-protein	gnl|CDD|377953	pfam08000, bPH_1, Bacterial PH domain. This family contains many bacterial hypothetical proteins. The structures of Structure 3hsa and Structure 3dcx show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response.	5.52371e-37
NZ_CP044548.2|WP_123093216.1|2499356_2499707_-|cell-division-protein-CrgA	gnl|CDD|377706	pfam06781, CrgA, Cell division protein CrgA. CrgA is a trans-membrane (TM) protein, first described in Streptomyces as being required for sporulation through the coordination of several aspects of reproductive growth. In Mtb (Mycobacterium tuberculosis ) CrgA is a central component of the divisome, and consists of 93 residues with two predicted TM helices (TM1: residues 29-51; and TM2: residues 66-88). CrgA facilitates the recruitment of the proteins essential for peptidoglycan synthesis to the divisome and also stabilizes the divisome. Reduced production of CrgA results in elongated cells and reduced growth rate, and loss of CrgA impairs peptidoglycan synthesis. CrgA has homologs in other actinomycetes.	8.29586e-31
NZ_CP044548.2|WP_123093214.1|2500613_2501270_+|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	2.06671e-115
NZ_CP044548.2|WP_123093251.1|2501399_2502362_+|ribonuclease-BN	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	1.72489e-26
NZ_CP044548.2|WP_123093223.1|2493403_2493928_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|237125	PRK12519, PRK12519, RNA polymerase sigma factor; Provisional.	1.95549e-27
NZ_CP044548.2|WP_123093250.1|2509010_2510006_-|DUF3662-domain-containing-protein	gnl|CDD|378850	pfam12401, DUF3662, Protein of unknown function (DUF2662). This domain family is found in bacteria, and is approximately 120 amino acids in length. The family is found in association with pfam00498.	8.40799e-42
NZ_CP044548.2|WP_123093213.1|2502375_2504307_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.6053e-120
NZ_CP044548.2|WP_163562446.1|2493992_2494700_-|class-F-sortase	gnl|CDD|320678	cd05829, Sortase_F, Sortase domain found in the class F family of sortases. Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.	3.46584e-50
NZ_CP044548.2|WP_123093212.1|2504374_2505829_-|penicillin-binding-protein-2	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	8.17156e-99
NZ_CP044548.2|WP_123093225.1|2492212_2492575_+|tRNA-binding-protein	gnl|CDD|182232	PRK10089, PRK10089, chaperone CsaA.	3.00731e-58
NZ_CP044548.2|WP_123093217.1|2498163_2499027_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	3.83445e-34
NZ_CP044548.2|WP_123093218.1|2497620_2498139_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	2.70805e-62
NZ_CP044548.2|WP_123093210.1|2508446_2508929_-|FHA-domain-containing-protein	gnl|CDD|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	7.10408e-19

Protein sequences

>NZ_CP044548.2|WP_123093217.1|2498163_2499027_+|rhomboid-family-intramembrane-serine-protease
MSEQPISGPPPTCPRHPDRVSYVRCQRCGRPACSDCQRPAAVGVQCVDCVREAARADRPTLTPLGGRASRSDTPYLTRVIVAICVLVYLGELATPQVYGEGALAAFLAVDQPWRLLTSAFLHSPSQIFHIVFNMMALWFVGPYLEGLLGRARFLGLYLVSALAGSVTYLLFQPVGSTQGVVGASGAVFGLFGALVVLQRHLGRDSSAMVGTIAINAVLGFVIPNVAWQAHLGGLIAGAAIAAGFALARQRRAPAIAWGTLGAVAGLTLALFVVKYVILAPAVVIPIA
>NZ_CP044548.2|WP_123093218.1|2497620_2498139_+|peptidylprolyl-isomerase
MQAILHTNHGDITIELFPDIAPKTVDSFVGLAKGTKEYKDDAGRTNPTPFYDGLVFHRIISGFMIQGGDPLGEGFGGPGYTFDDEPHPEHTFDKPYQLAMANAGKRMGKGTNGSQFFITVAPTQFLYGKHTVFGEVADGPSREVVDKIAAVRTGANDKPAEPVVMESVEIVD
>NZ_CP044548.2|WP_123093219.1|2496350_2497475_-|hypothetical-protein
MFRTESKVEKGRVAAHEGAESGVAKIHTLIDKVAEGAETGSDRAAGLGAAASAKSADLRAQAADASKDVRKDAKKTGKQLRKDASKSTKQLRKDAKKAGKRAGDGAHDLRDTIVDDVLPKVVATATGLAATGAATTKSVADEAGKRAPEAFHALKDDHDTHAALAAIKGETRRSGRSWKVLLLALVAGGVAFYVAKKQQKPKKDPWAVPAGDPYKAPDTGRASSVTPAAPVTDGAAATSQTPIADEVVADEVVSTDDVPVAGSAAPSLDAGDGPVLGEGDTTHAAMTGHPDGVDDQGVPSTSTSASTGSGDTGLGETRPLSNEEIDELASDDPTQAHVGSPDETAQTNGEGGDAWSSARDWADDGQNPDDKRGC
>NZ_CP044548.2|WP_123093220.1|2495712_2496087_+|PH-domain-containing-protein
METAAITSWTLIEEIPIPQDVLSLLVEGEQAVAAYKTFRDSAIFTTKRLIVRDAQGLKGKKVEVYSLPYSRIDMWSSENAGGMFDFNSELEMWTRAGHIKIKLDKKIDIRRLDQLIAWAVLGAS
>NZ_CP044548.2|WP_123093221.1|2494735_2495536_-|DUF4397-domain-containing-protein
MGVTAAMALVGLSAAAPAHAADDAHVSILHAVPGATVDVYVNGDALLTDFKPGTLTDPQALPEGQYDLKVTAAGAGADGDAIVEANDVDVPAGANITVVAHLDADDQPALTPFVNDTSAIDAGKARLTVRHTAAAPAVDVRANEEVVFSNLTNPNEESADVAAGTVSADVVLAGTDTVAIGPADLNLGEGTNTIVYAWGSAKDKNLKLATQSISGMHSSPNGVPSGSGGQVAAADETGRYAMATLGALAAGGLVFFAGRRKSRVQA
>NZ_CP044548.2|WP_163562446.1|2493992_2494700_-|class-F-sortase
MIGLAAVTALLVGAVLLFLTRPSADDAGTVDAALSGPSATGGSSSTSSTAPSPTSSETSPSPGSTKAAKAPRTAVATAPATPSAAPPAPTSVSVPELDATLPVRPVGVDTTGAMSIPEDPRQAGWYKFGSAPGQDGATVITAHVDTKELGPGPLARLDTLSKGDAVTVRTSAGTTTYRVREVVLARKTELDLDALFRRSGRPALHLVTCGGAFDPKTGHYEDNVVAIADPATGRE
>NZ_CP044548.2|WP_123093223.1|2493403_2493928_-|sigma-70-family-RNA-polymerase-sigma-factor
MAVQLSEGQPSAIEAAYQHYSHLIYTIALRALGDRQDAEDVTQQVFLAAWRGAQNLRPSPTALPGWLVGIARHKIADVLQARGQESRRLRAVADETGRIGPAPARDHALEIAIIAELEAMGDPRGPILRMTIMEGLSHSDVADRLDLPLGTVKSHARRGLIHLRQVLKEVRDDD
>NZ_CP044548.2|WP_123093224.1|2492589_2493411_-|anti-sigma-factor
MTETMRWTDGHPDEEALADHAFDVRDGLPGDPDVVAHVAGCAQCSADLAELSDLARGRVPGEGGPLARAVDDRGEIAWQYPDERVWDAIAAEMGRPVLTVVGEERPARAVPAPADRAGDGPTPAAERSAGGFSLRRTVPWLAGVAALVVGLALGRGIGDPSPEVTEVARLSTVDDAKDARGQAELVRAGDGLQLRVQPQSLPKGPGYLEVWLLNTDGSRMVSVGVLDGDSPQDYTVTQDLIDEGYTVVDISREAFDDKPEHSGDSLARGTLGA
>NZ_CP044548.2|WP_123093225.1|2492212_2492575_+|tRNA-binding-protein
MDEPQDAEATEPLDWATFERVDLRVGTITSAETNARARKPAYVLQVDLGPLGTKTSSAQITELYEPEDLVGRQVLCVVNFPPKRIAGVVSEVLVTGAPDAEGRIVLATTASTVPDGSRLA
>NZ_CP044548.2|WP_148041616.1|2491334_2492162_+|hypothetical-protein
MPAARLLVAPALIAASLLVVAPPAASADGVDPSTVRATQLDEPFHYDTGDHLTGSREVPTTRRYGYGRPVFLVGDSMAGQLADGLRRSTAGQHRALLPRTKSGGIFRLPAGDSPSGRWSARVRNQIRAEARDGRRPIVVLAGRGLGTSTQIRSTVWRLRADGATVHLVTASPLPADVATLPSCVVASSSPTTRCRFRLTDADAGRTATLIAARQASPRISVLDLKPLAARGSGPTYSPVHTGADGPVQIYRGVSNHLTATWSREILAGRLAALTR
>NZ_CP044548.2|WP_123093216.1|2499356_2499707_-|cell-division-protein-CrgA
MAPSKKNEDELEQTEKVASTSTSAGKRSGDPRRRAEAEAEADKPVKAKREKVKAQKIGNPSWYVPVMLGLMILGLIWVVTFYITQQEYPVAAWGQWNLGAGFALMMAGFVMTTRWK
>NZ_CP044548.2|WP_123093215.1|2499805_2500594_+|DUF881-domain-containing-protein
MGEHEAPSRPHGPRRLVRWYLDHRPTRWSAGVPVIALCAGLLFSVSGTTARGGDLRSEVTTLPALIRERTHDNAVKARRAEELRSTVTALTKERSPGNQEIDRISRDTANAAPKAGFEEVRGPSVSVSLDDAPLDADQIPEGFDVDDVVVHQQDVQGVVNALWRGGAEAMMIQDQRIISTSAVRCVGNTLILQGRVYSPPFVITAIGDRDALRASLDEDPTVSIYREYVDQIGLGYEVTSSEETTLPAYAGQSQLAHARAAR
>NZ_CP044548.2|WP_123093214.1|2500613_2501270_+|aminodeoxychorismate/anthranilate-synthase-component-II
MSTVLVVDNYDSFVFTIVGYLQQLGAQTTVVRNDAVSPADGADFDGVLVSPGPGTPEQAGVSMAMIEACAERAQPMLGVCLGHQALGVVCGATVGRAPELLHGKTSQVEHDGTGVLAGLPAPFTATRYHSLTIEPETIPDTLVPNGRTASGIVMAAHHRDLPLHGVQFHPESVLTQGGHRILANWLELLGDEGTVARSEGLSPLVRDAEGVARMVAAG
>NZ_CP044548.2|WP_123093251.1|2501399_2502362_+|ribonuclease-BN
MPIAVVYKFFDDFGGYLAALITYYGFLSLFPLLLLLSTLLGIVLEGHPQWQQRILDSALSEFPIVGDELRQTGTLGGGTLGVIIGSVAAIYGGLGVAQALQYAMNTAWMVPRNSRPNPFVSRARGLMIILTAGLAVVATSVLTQVANRLVVGAWQSLAVDLGSVVLNAGVFTFLFIISTTRAPTPRQVLPGAVIASILFLLLQNVGVLYVGTVVSRASNVSSVFAIVLGLLIFIYSNAVVILLCVEINVVLAERLWPRALLTIFTDDVELTDADRRAYRGQARAQRLKGFEKISVSFERPRPDVPEDDEGGAEAPPSTAS
>NZ_CP044548.2|WP_123093213.1|2502375_2504307_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTTSTPRLLGGRYELGELIGRGGMAEVHRGYDTRLGRPVAVKILRSDHARDTSFLHRFRREAQSVAGLNHRSIVAVYDSGEDRTTESGGAGLSVPYIVMELVEGQTLREVLNDQGPLAPAEAARICEGVLDALSYSHRMGIVHRDIKPGNVMLTADGTVKVMDFGIARAVADTQATMTQTAAVIGTAQYVSPEQARGETVDNRSDVYSVGCLLFELMTGTTPYTGEPISLTYQHVNAPIPLPSSLEPTVSSDLDAVVAAALTKDRDERYQDASDMADDLRAVRAGRPVSELAQGALAAVAGAGALEADPTVALAAAAPAQHLGDTSTFRPIQDPPTPLEPERRRRGGLGWLLALLLLIPVAALGWYVWDSNQPPEVVRVAAPQLVGLDEDAAEAKLTDLGLDGDRSEANNAAPEGEVFEQSVPEGEMVDEGSTIAYTVSQGPEQATVPQVVGQSRADAEKAIRDAGLEVGDVTFEDSNEQKKNRVISVSPGQSEQVEAGSTVDLVVASGDVQLPDFVGQPISDARPEIFALGLLTEEVTVPSDEPAGQILSQDPGAGKVAQGRTVKIEIAGPQDKTETTTVTPPPPSTSETTPPETSDPSTTSPPEETTDPGDGEEGDQGDQTPGGPASPSTPNPRSTTAQTP
>NZ_CP044548.2|WP_123093212.1|2504374_2505829_-|penicillin-binding-protein-2
MNEPIRRLSMLAALLFTALLVSSTWLQVVGAEAINDRPDNRRTALKNYGQERGQILLGGQPIARSVPSDDELQWQRVYASPETYAHITGYYSFEYGAGGGLEGAANSLLSGTDDTLFYGRVSDILSGKASKGASLELTIDPQAQRAAKEALGDQRGAVVAMDPRTGAILAMYSSPTYSPTPLVSHEQGTAAKAWESLNADSSRPLVNRAIGGNLYPPGSVFKVVTAAAAIESGDYDESSSIPGPAVLDLPQTDVGLPNSHPGACGPNDRVTLAVAMQDSCNTAFGWLGMELGGDTVGDQASKFGFGDKLEIPMDVTPSTFPTGLNPPQEAQSAIGQYDVRVTPLQVAMMSSAVANDGVVMRPYVVERVQGDDLSVISDTKPEQLSRAIDPETATELTDMMKLVVERGTGTQAAVPGTSVAGKTGTAEHAEGAAPHAWFTGFAPADNPKVAVAVVVEDGGRAGNEAYGGSVAGPISAAVMKAVLE
>NZ_CP044548.2|WP_068272308.1|2505825_2507202_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MKTITTIAPKRGRNVELLLVALAIGVVVLAYINVEVAANGSVPPDLLAHTGMLAAIALVFHVVLRWRASYADPLVLPILTLLNGIGLVMIHRLDLAAGRDFSEGYALKQLQWTALGVALALTVLVALRDHRVLRRYTYTAGLLGLVLLLLPLLPIIGHDVYGANIWIKIGPFTFQPAEVAKICFAVFFAGYLVQTRDVLALAGRKVLGLTLPRGRDLGPILVAWVASVLVLVLETDLGTSLLLFGLFVSMLYVATERVSWIAIGLSLAAFGAFVAYRLFPHLQTRVLCWVDPFSEEGTRQCGQLVSGLMGLSAGGLLGTGLGRGRPWSTPLPETDFIFNSLGEELGLVGIMAIIALYAILVERGLRSAIGLRDGFGKLLATGLAFTVALQVFVVVGGVTRVIPLTGLTLPFVAYGGSSLLANWTLAAILLRISDHARRPEPELDPASMDAPTEVVSTR
>NZ_CP044548.2|WP_123093211.1|2507198_2508443_-|Stp1/IreP-family-PP2C-type-Ser/Thr-phosphatase
MAIGLRYAARSDVGLVRSDNQDSGYAGPHLLVVADGMGGHAGGDIASATVITELVELDHDSLGASEASAQLGKAIRRANREIARIAEERKELSGMGTTTTALMRARNKLILAHIGDSRAYLLRDGTVTQITTDHSFVQTLIDEGRITEEEASTHPQRSVVTRVLTGDEDDDPDVGAREARLGDRYLLCSDGLSGFVARDTIAEQLSSGRTPAETADDLVALALRAGAPDNVTVIVADVVDSADGTPPSTQPQVVGSASMRSSSTRAIPTTPAEKAAALVRPETPEPDLELAEEGSTRRGRWLRRVAALGVVALVLGAILYGAWAWTQQQYYIAGQDGRVTIYRGIASDLGPIPLSSAVEQTDVMLSDLPDFYRSSIEESVSVDSERDAQKKVDDLRVAAKRCAELRSEGEPCGR
>NZ_CP044548.2|WP_123093210.1|2508446_2508929_-|FHA-domain-containing-protein
MSELTVTVLRLGLLILLWAFVLSLAGVLRSDLYGTRVIARQGSASSRRSRKEKRAADTPRRNPRTPTHLVITSGALAGTSLPLRDKGVLIGRNPECTLVLDDDFASGRHARIIRGDDGWYVEDLGSTNGTFIGEFRVGEAVPVEAGTTVRIGKTRLELRS
>NZ_CP044548.2|WP_123093250.1|2509010_2510006_-|DUF3662-domain-containing-protein
MERKLERTVNGVFAKAFRSEVQPLELASAVRRAMDDRATLIGRGRTAVPNLFTIELSPGDYDRLTEYDEELEDELIAAAQEHAETQRYRPGGPLQVIFESDDELETGVFRVRPATARQLVEDPSAVREYREEYVETEGEDYDEYSAPVPQGRAQVPAAPTPAPAQAAPSADEWWDDDVEDDEWEVPTSARGAAATPAPAPAPVRAPQPRAPEPRAPEPRTPEPARAAARRPRVQDLPWLEVDGERYPLMSAMTVLGRDESADVVLDDPGISRRHAEVRVTNDGPHQVAHLRDLGSTNGSYVNGEQVDACPLHDGDRITVGRTSVIFRLARR

Crispr_ID: NZ_CP044548_13

• CRISPR_ID: NZ_CP044548_13
• CRISPR_location: 2717556-2717640
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP044548_13

Consensus_repeat	Method
TTCCCGCCCAGGGCGGGAAAGTG	CRISPRCasFinder

spacers of NZ_CP044548_13

>13.1|2717579|39|NZ_CP044548|CRISPRCasFinder
CGACCTCGGGAAAGAACATGTCCTTCCCGAGGTCGAATG

CRISPR arrays and Neighbor proteins around NZ_CP044548_13

CRISPR arrays

The CRISPR arrays of NZ_CP044548_13

>merge|NZ_CP044548|13|2717556-2717640|CRISPRCasFinder
TTCCCGCCCAGGGCGGGAAAGTGCGACCTCGGGAAAGAACATGTCCTTCCCGAGGTCGAATGTTCCCGCCCTGGGCGGGAAAGTG

>NZ_CP044548|13|13|2717556-2717640|CRISPRCasFinder
TTCCCGCCCAGGGCGGGAAAGTG	CGACCTCGGGAAAGAACATGTCCTTCCCGAGGTCGAATG
TTCCCGCCCTGGGCGGGAAAGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044548.2|WP_163562454.1|2716264_2717518_+|YncE-family-protein	unknown	unknown	gnl|CDD|225926
NZ_CP044548.2|WP_123092638.1|2723093_2723849_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|181324
NZ_CP044548.2|WP_123092637.1|2723906_2724629_+|hypothetical-protein	unknown	unknown	gnl|CDD|372667
NZ_CP044548.2|WP_123092648.1|2708950_2710216_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|181262
NZ_CP044548.2|WP_123092650.1|2706603_2707437_-|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl|CDD|224238
NZ_CP044548.2|WP_123092745.1|2710288_2711320_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123092639.1|2722033_2722903_+|carbohydrate-kinase-family-protein	unknown	unknown	gnl|CDD|238573
NZ_CP044548.2|WP_123092641.1|2718641_2719544_+|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl|CDD|224513
NZ_CP044548.2|WP_123092644.1|2715288_2716098_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP044548.2|WP_123092743.1|2721179_2722028_+|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl|CDD|377251
NZ_CP044548.2|WP_123092744.1|2720507_2721011_+|hypothetical-protein	unknown	unknown	gnl|CDD|367797
NZ_CP044548.2|WP_123092640.1|2719540_2720482_+|DUF2183-domain-containing-protein	unknown	unknown	gnl|CDD|227187
NZ_CP044548.2|WP_123092647.1|2711593_2712391_+|Asp/Glu-racemase	unknown	unknown	gnl|CDD|226004
NZ_CP044548.2|WP_123092649.1|2707507_2708902_-|MFS-transporter	unknown	unknown	gnl|CDD|273327
NZ_CP044548.2|WP_123092746.1|2704192_2706547_-|xanthine-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|376913
NZ_CP044548.2|WP_123092646.1|2712449_2713589_+|XshC-Cox1-family-protein	unknown	unknown	gnl|CDD|379212
NZ_CP044548.2|WP_123092642.1|2717657_2718146_-|SRPBCC-domain-containing-protein	unknown	unknown	gnl|CDD|176856
NZ_CP044548.2|WP_068272399.1|2718151_2718493_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP044548.2|WP_123092645.1|2713749_2715258_-|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_CP044548.2|WP_068272405.1|2724821_2725409_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP044548.2|WP_068272399.1|2718151_2718493_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	7.3e-15	50.1	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP044548.2|WP_163562454.1|2716264_2717518_+|YncE-family-protein	gnl|CDD|225926	COG3391, COG3391, Uncharacterized conserved protein [Function unknown].	2.83726e-22
NZ_CP044548.2|WP_123092638.1|2723093_2723849_+|SDR-family-oxidoreductase	gnl|CDD|181324	PRK08251, PRK08251, SDR family oxidoreductase.	1.46731e-125
NZ_CP044548.2|WP_123092637.1|2723906_2724629_+|hypothetical-protein	gnl|CDD|372667	pfam13669, Glyoxalase_4, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	4.05111e-10
NZ_CP044548.2|WP_123092648.1|2708950_2710216_-|FAD-dependent-oxidoreductase	gnl|CDD|181262	PRK08163, PRK08163, 3-hydroxybenzoate 6-monooxygenase.	2.52382e-79
NZ_CP044548.2|WP_123092650.1|2706603_2707437_-|xanthine-dehydrogenase-family-protein-subunit-M	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	1.67767e-52
NZ_CP044548.2|WP_123092639.1|2722033_2722903_+|carbohydrate-kinase-family-protein	gnl|CDD|238573	cd01168, adenosine_kinase, Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine levels and the preservation of intracellular adenylate pools. Adenosine kinase is involved in the purine salvage pathway. .	3.88424e-38
NZ_CP044548.2|WP_123092641.1|2718641_2719544_+|diacylglycerol-kinase-family-lipid-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	2.95644e-38
NZ_CP044548.2|WP_123092744.1|2720507_2721011_+|hypothetical-protein	gnl|CDD|367797	pfam04073, tRNA_edit, Aminoacyl-tRNA editing domain. This domain is found either on its own or in association with the tRNA synthetase class II core domain (pfam00587). It is involved in the tRNA editing of mis-charged tRNAs including Cys-tRNA(Pro), Cys-tRNA(Cys), Ala-tRNA(Pro). The structure of this domain shows a novel fold.	1.2915e-26
NZ_CP044548.2|WP_123092743.1|2721179_2722028_+|pseudouridine-5'-phosphate-glycosidase	gnl|CDD|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	4.23101e-141
NZ_CP044548.2|WP_123092640.1|2719540_2720482_+|DUF2183-domain-containing-protein	gnl|CDD|227187	COG4850, COG4850, Uncharacterized conserved protein [Function unknown].	7.27466e-06
NZ_CP044548.2|WP_123092647.1|2711593_2712391_+|Asp/Glu-racemase	gnl|CDD|226004	COG3473, COG3473, Maleate cis-trans isomerase [Secondary metabolites biosynthesis, transport, and catabolism].	1.05452e-75
NZ_CP044548.2|WP_123092649.1|2707507_2708902_-|MFS-transporter	gnl|CDD|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.98801e-60
NZ_CP044548.2|WP_123092746.1|2704192_2706547_-|xanthine-dehydrogenase-family-protein	gnl|CDD|376913	pfam02738, Ald_Xan_dh_C2, Molybdopterin-binding domain of aldehyde dehydrogenase.	0
NZ_CP044548.2|WP_123092646.1|2712449_2713589_+|XshC-Cox1-family-protein	gnl|CDD|379212	pfam13478, XdhC_C, XdhC Rossmann domain. This entry is the rossmann domain found in the Xanthine dehydrogenase accessory protein.	1.16173e-50
NZ_CP044548.2|WP_123092642.1|2717657_2718146_-|SRPBCC-domain-containing-protein	gnl|CDD|176856	cd07814, SRPBCC_CalC_Aha1-like, Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Micromonospora echinospora CalC, human Aha1, and related proteins. Proteins in this group belong to the SRPBCC domain superfamily of proteins, which bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. MeCalC confers resistance to the enediyne, calicheamicin gamma 1 (CLM), by a self sacrificing mechanism which results in inactivation of both CalC and the highly reactive diradical enediyne species. MeCalC can also inactivate two other enediynes, shishijimicin and namenamicin. A crucial Gly of the MeCalC CLM resistance mechanism is not conserved in this subgroup. This family also includes the C-terminal, Bet v1-like domain of Aha1, one of several co-chaperones, which regulate the dimeric chaperone Hsp90. Aha1 promotes dimerization of the N-terminal domains of Hsp90, and stimulates its low intrinsic ATPase activity, and may regulate the dwell time of Hsp90 with client proteins. Aha1 can act as either a positive or negative regulator of chaperone-dependent activation, depending on the client protein, but the mechanisms by which these opposing functions are achieved are unclear. Aha1 is upregulated in a number of tumor lines co-incident with the activation of several signaling kinases.	1.98959e-30
NZ_CP044548.2|WP_068272399.1|2718151_2718493_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.97726e-14
NZ_CP044548.2|WP_123092645.1|2713749_2715258_-|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.52358e-86
NZ_CP044548.2|WP_068272405.1|2724821_2725409_-|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	5.28825e-13

Protein sequences

>NZ_CP044548.2|WP_163562454.1|2716264_2717518_+|YncE-family-protein
MYVDDDPVYKRRRLVALAVVIAVVLGLCALGRVLLGGDDAEPAAAATPVAAAAPAKKATTVEQAAPPLRPQEEQGEPAGTADTELVRVQRITGGLTPKSVVASGQGLVLAQNMMYSHTVTAYRPDGARVATVSDTVDLSDFGVKGHPGRSKGAPVEVAFSPDGRTAWVSQYSMYGKGFAPEGADSCTSGAGISNSYLYELDTSTFEVRRVVEVGAVPKYVAVTPDGRSVLVSNWCSMDLTVVDAAKGTVTRTIPTGGQHPRGIAVSPDSTTAYVAIMGSDRTVAVDLAKGSVRTLAETGDKPRHVVISPKGDYLYVTNSGAATVSKVEVSSGEVVAEAKTAADPRSTAISPDGAALYVVEYGAARVSKILTADMELVDSEPTDGLPIGVTYEPTTKRVWVACYSGSIVVYDDSRRGA
>NZ_CP044548.2|WP_123092644.1|2715288_2716098_-|hypothetical-protein
MTDTTDETPHIDIEDPQVWVLDIDGRRHEVRTSQRGFRNLATWSVDGVEVASSSGSADSLELVVPDDHELVEEIGAMKARFAATGRPRRVTHFAGAKSAALPRALVGTGGTDLDPEPGSRAHRREEWAVRHPVLASADDVLGGAGKVVVPLLLAALLPVLGRLLPDWDLDLPSVDLPSIPWPDLPSIPWPDLSVPWPDVTLPGWVGALLGAAKVLWPLLLGIAVAVGEHRRRRRNAAARDDREAQQTGEGARDGDADAGAARPGLDEEE
>NZ_CP044548.2|WP_123092645.1|2713749_2715258_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTTARPAPAPTSSTNAQGPDNPWPALWALVVGFFMILVDASIVSIATPALMADFGADIESVVWVTSAYLLAYAVPLLITGRLGDRFGPKRIYLVGLVVFTLASLACGLSGSITALVVARVVQGLGAAMMTPQTMSVITRTFPVDRRGSAMALWGATAGVAFLVGPLLGGVLLDSVGWEWIFFINVPVGIAGLVAAWRLVPDLETRGHSFDWVGVVLSAVGLFAVVFAVQEGERYDWGTITGPLSVPLLVVVGLVVLAAFVWWQSRVRPEPLVPLGLFRDRNFSLSNIAITTMGLAITAMMFPLLVWLQSVRGLSPTQAALVLAPQAIASIVLARPVGQLVDRIHPRILPTIGLSGFAVTLVVLALLMRANAPLWAVVLTSTFVGVTGASIWGPLATTANRNLPVQLAGAGSGVYNTTRQVGSVVGSAAIAALMSSRIAANVGGGAGQGMSMEGAGASAQQIPPAVADALSKAFGEAMLLPAAVLVVGALAAAGLERMSHTKG
>NZ_CP044548.2|WP_123092646.1|2712449_2713589_+|XshC-Cox1-family-protein
MRDVLDDLVESWRAGRTVGLATLVETWRSAPRQPGAAMLVDEGRAVGSVSGGCVEGAVYELAQEVATAGAPQLVRYGVSDGDALEVGLTCGGTLELFVQPVSRDLFPELGAIAQDIRSGRPVAVATVVEHTDAAFVGRRLVVHPGADEREEVDAAGFPGGRRGLDAVTDDARGLLAQGTPELLTYGTSGERRGEGMRVFVEVFAPRPRLVVFGAIDFASAMVRQGRLLGYHVTVCDARPTFATAARLPGADEVVVRWPHQYLREEAEAGRIDRRTALTVLTHDPKFDIPLLEVALRLDVAFVGAMGSRRTHEEREAQLRAAGVTEAELARLSSPIGLDLGARTPEETAVSIAAEIIALQWGGAGTRLSHRDGPIHHPHA
>NZ_CP044548.2|WP_123092647.1|2711593_2712391_+|Asp/Glu-racemase
MTTAAQPLPTTSATTRHIGMIVPSSNLTMETELPQIFGRRELVHPQDHFVFHSSRMRMKHVTPEELVKMNAQTERASLELADARPDVVASACLVAIMAQGAGYHCTAEDQMRAALDSEGVSAPVISSAGALLRALTALGARKVVMVTPYMKPLTQLVADYVVDAGFEVLDTLSLEVSDNLEVARLDPADLTEHWKRLDAQALEDADALVLSACVQMPSLPAIQAVEDAYGKPVLSAATATAWSILTDLGLPAEAPEAGSLLSGRY
>NZ_CP044548.2|WP_123092745.1|2710288_2711320_-|hypothetical-protein
MTQLTSADLVQAFTDELRLCKLEPGEHVVVLSEPSSRQDYVAASFAAAKACGAHVIAATVPGGNPDPVPSTHTGAGPGLSSVLQDTVAQQLLKQADLVLDLTREGFIHAPIQDEILQGGTRILFVCDAPDVLVRNMPTAADKPRVLSGQQLVHDSSTMRVTSAAGTDLTVDLTNVRCDYQVGFTDDPGRWDHWPSTMVLCWPEISDGQIVIAPGDILLPFKEYVREPVTLTVSGGHIERVSGGADANMLETYFADSDDKWARYLSHMGWGLMKTADWFAQAMYAKHEVMGMEARAFAGNFLWSTGPHPVLHRDSYAHLDIAMRGCTVTLDDTTVVADGTLVES
>NZ_CP044548.2|WP_123092648.1|2708950_2710216_-|FAD-dependent-oxidoreductase
MSMSQSLEVVVVGGGLGGLTAALAMRQQGLRVTVLERADALGEVGAGIQTAPNAARVLMGLGLLPELERIKTEPQDQVRRRWKDGSVIGLTALGSYVKDTYNAPYWHYHRADLHQVIHEACVDPQGHGPVVEVITSAEVREVDQSDPARPVVVTADGRRVAGDVVVGADGIRSAVRDAIGGEDTLVFSGEMAYRVLVPGDAIREDPATRWLVDRFQSTIWYGPDRHLVHYMIRGGEMLNIVAIVPADDGIAQSWSRPATTDELLEQYQDWDDRVAAMLSKAEHCSAWAMYHRRRDPLWVDGQVALLGDACHAMLPYQAQGASQAMEDAAVLAEELGAVSRADIPSALARYVSRRSKHAGMVQDASLRNKDFYHLPDGPEQEERDAKLAAFNGESDVSYHWLWSGSPLNNADMESYHYQFRR
>NZ_CP044548.2|WP_123092649.1|2707507_2708902_-|MFS-transporter
MRTGDQIVQDLPWRWNVQGKIFLIGGLGYLFDAWDIALNGFLTPLVGLEFDLSPGERGYVATANLIGMAVGAITWGSIADRLGRKRAFSITLMIFALFSVLGAFSPTYSIFLLFRFLAGFGLGGCIPVDYAIVGEFSPRAVRGKVLTALDLFWPIGATFAGLSAWALLNVEHNWRVMLGIMVLPALLTFWVRRGIPESPIYLAKVGREAEAREIIDRLVVETGATPEPYEIKPPVVQAKVNGVVAASRQLRTIWGQLPMITFMAWLLFVSIMVVYYAALSWLPTLLRDAGATFTVAFLGSTIMSAIGIFGCALSAVLVDITGRKWLLGVSASLGSVALVGIGYTIDMPGTALIAIGIFGFVIQVAIPVLYAYIAEIYPTEVRASGFAWASSMSRIATGLAPIVFSAWAFPTLGLVNTFLVLMGAVFVAVAVMAKFGPETKGMELDAVVEDVEAAPAPARAGALD
>NZ_CP044548.2|WP_123092650.1|2706603_2707437_-|xanthine-dehydrogenase-family-protein-subunit-M
MKPAPVSYHRASSVRDAVALLTSLGEEAKVIAGGQSLVPMMSFRLARPEHLVDITRIPGLDTLEVVGDELHIGALVTHQAVLESDVVRGSRGHRVVATTMRHVGHLPIRTRGTVGGSIAHADGSAEWPLLAVLLGARVVVEGSSGEREIPAAELFYGLYTTSIEPDEIVVRVIFPAATGETGFAEHGLRHGDFALASAGVVLPSSPGATDARVVVSGAAPAPTRLPHAEAALAADADEDRLRRAVTQDLDDLEVDDDYQRDLVTGMVTRAVQEARQS
>NZ_CP044548.2|WP_123092746.1|2704192_2706547_-|xanthine-dehydrogenase-family-protein
MTRDGAFIGASVRRREDPRLLTGAGRFVDDIDLTGQLHAQFVRSRVAFGRILDVDLEATRAVPGVVAAFAADDLVMAPITALLDRPVEQFRPTEMPVLAHDTVRFIGEPVAIVVAKTPYAAEDGVEAARVEYETYDAIVAADAAMAPGARRLHDGAPDNVLVDVSLFDTPGVDDAFAQAAEVVEISIDTGRQNALPMETRAALAQWDERESQLVLHTPTQVPHLVRTATAASLGLPERQVRVVVPDMGGGFGIKCVVGREEMVVAAAARRLRRPVKWVEDRKDALTASFLAREQHYTARAAFAQDGEFLALDVEVVCDMGAYSCYPFTAGIEPLMASGEMPGVYRLGAYRVHGLAVATNKAPTAPYRGVSRPQYVMLLEQIMDRAGHQLGLDPLDVRRRNLITDFPYTSINSITYDPGSYLESLDLCEQMVREEGWFERQAQAREEGRYVGIGFSCFSERTGYGSSAFAARKMLVVPGFDISDIRMDLDGTITVTSGTMNHGQSHETTMAQIVADTLKVDVERVKLHQGDTDRITYGFGTFASRSAVIGGSAVQLASRALGEDLVEIAAHLLETNVDNLELRDGAVRRRDEPEEGVTYEEIADVAYLQAHRLPKGVSPGLHATASFDVTNDGTFSNATQAAVVELDPVSGAVRILRYFCVEDCGVAINPQVVEGQARGGIAQGIAGALYEEITYDANGEPSCASFMDYCVPTAMETPDIRIAHLETPCIYNETGAKGAGEGGTIGAPAAVLGAVNDALRPTGALLGRTPITPRAVHAAITGGTR
>NZ_CP044548.2|WP_123092642.1|2717657_2718146_-|SRPBCC-domain-containing-protein
MPVTDITPDVEGRTLTVVADFAAPVDRVWQVYADPRQLEQVWGPPDYPATFVEHSLTPGGRMVYYMTSPEGEKYYGYWEVGDVEEPRRFDFADGFATDEAGTPAPELPVSRATMTFEATDGGTRLTTVSTYESAEALQQVLDMGVVEGTAGAMNQIDALLAA
>NZ_CP044548.2|WP_068272399.1|2718151_2718493_-|winged-helix-turn-helix-transcriptional-regulator
MFHALADRTRRDILRRVLAGEHSVSALAEKYDMSFAAVQKHVAVLERAGLITKRREGRTAMASGDVEAVRSVGQLLGEIEQVWRGRVARIDDLLLRGSTDVSPTTPPEQDRED
>NZ_CP044548.2|WP_123092641.1|2718641_2719544_+|diacylglycerol-kinase-family-lipid-kinase
MTRVAVVVNPSKTRAKGVADRVAQGCAERGWPEPEVLETAVDSTGRDQAAAAAGAGAELVLACGGDGTVRAVAHGLAGTGAAMALVPVGTANLLAHNLGLATRDTGRAVDTALDGRRRPLDLGLARLGEDGSEHPFVVLAGIGHDAATVADTRDDLKHRIGWPAYVTPAARHALRRPVPVRVRLDDGPARDVVAWSVLAASCGRVRAGVQIAPGALLDDGLLDVLEVTVARPVGWLPVAAKGVLGLRRDVPGLRTRRAAELEVTADQPLHVQLDGDIMGRVDRLRVRVQRRAIDVVGGAR
>NZ_CP044548.2|WP_123092640.1|2719540_2720482_+|DUF2183-domain-containing-protein
MSADLVTEVHELQEGWTSAADERRLAEIFLGVHGVELTELKNAINRRDDHHDLEELLFDDVDDDEIRARVLAHLAAEAQALGRVGVKVLSDIDDTVFPMIHETRYPRGHTPVPGVLAFLQALDDGPVDNPLSRGDLTFVTARPELAMGLVEGSTKDALRTAGVVSSSVLAGEVLGLRSKDAMADVKLANVERYRQAFPEYGVVFVGDTGQGDVLVGTRMREAYPQDCPAVFVHDVVATAQPERDRLAALGVHVVDTYVGAAGVARGLGLVSDAGVAEVTEQALAELDEVAWESAEQERDTRALFERDVGGLLG
>NZ_CP044548.2|WP_123092744.1|2720507_2721011_+|hypothetical-protein
MSEHEPAETSDGERRAVAAMLAAGIEHEVTRHGRVGSLAEAAAARGVEPADIVKTLVVRRGDDDHLFVLVPGDREIDWPLLREHLGVSRLSMPDAGTARDATGYERGTITPFGSTHAWPVVADASILRPEGRRVSIGAGAHGVAATVPAARLVEVLGADVAGVTRPA
>NZ_CP044548.2|WP_123092743.1|2721179_2722028_+|pseudouridine-5'-phosphate-glycosidase
MESTIFTHGLPRPRNLEVALAAEEQVRAAGVVPATIGVVDGVATVGMSTAQVERLAGEDVMKASVRELPIARATGASAGTTIAATAFLAHAAGIEVFSTGGLGGVHHGASTTFDESADLVTLSRVPVVLVSSGAKAILDIPATLERFETLSVPVVGYRTLRYPGFYVHDSGYPLAQQVDSPEQVAALYRASRGLGLPASVLVGNPIPEGDSLDPVALDEVIERAWAAADDQGVRGQATTPFLLDFIQRATKGESLDANVALYRNNVALGCEVATALAVGVSG
>NZ_CP044548.2|WP_123092639.1|2722033_2722903_+|carbohydrate-kinase-family-protein
MLAVAGDLVQDVVVLTHEPLRRGSDVAAQVSTQRGGSAANVAAFAAASGTPTRFVGCVGDDVAGRALVAELAGHGVDVRVQERGTTGVIVVVVEQDGERTMYPSRGASALVESVDPGWLDGVEVLHLPLYGFDGGSTPDALAAAADTVRSAGGRVCVDLSSTLLVDRHGAGWVREVLARVAPTWVSANADEVHALGLDDPAWLDAHPVTVVLARAGADPTRVLRAGADALVVPVAPVDGVVDTTGAGDAFAAGFLGATLAGSELVAAVEAGHALARRVVTAAGAVLPPA
>NZ_CP044548.2|WP_123092638.1|2723093_2723849_+|SDR-family-oxidoreductase
MPTTLITGASSGLGAEMARQMAALGHDLALTARRTDRLDALQAEITAAHPGRRVETYPLDVTDDEAVLAVTRRVQEDFGTIERYVVNAGLGKGAPVGKGSHYANRETLTTNVLGAFAQAEAAMQVFREQKSGHLVIISSVTSVRGFPSSMTAYAASKAAVASLGEGIRSEMLGKPDLDIDVSVICPGYIRSEMNEKVEQKVRFMVDTETGVRSMVAAIEARRAKAFVPARPWAALAKVMQVAPLPVVRKLM
>NZ_CP044548.2|WP_123092637.1|2723906_2724629_+|hypothetical-protein
MSDTQRAQEVVGISGVSIASEDVDATREAWCRFAGIEHSPALVVGGVAVGVGPTVGGPEGLAAVTLAATDVSETLTLIGRRGLPVDGGVVDVAGTSWRVAGTTGQVDLDPRGGIEGVDHVVVSSTDPDRAAALYGARLGLELRLDRTMPEHRMRGLFFRAGDSVVEVVTRLDGEGDGGEGGADRLSGIAWRTPDVAAVRERLLGAEVDVSEVRPGRKQGTLVATVRDPDLRVPTLIVGPA
>NZ_CP044548.2|WP_068272405.1|2724821_2725409_-|TetR-family-transcriptional-regulator
MSEPERGRRAERKRVTRAALHRAALEIAHDEGVAAATVERVAERAGVSPRTFFNYFATKDDALSGVDPDLPAALAQALRERPQDEPLRDSLRAVLVERMATATREPQMWRMRAVVARESPSISVAVLGAGAQTARALADAAYAREGVDPADDIAPAVAVFTALGAVRAAIWTYGQRGFEGEIEPLVRECFEISGL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP044548_4	4.2|784716|15|NZ_CP044548|CRISPRCasFinder	784716-784730	15	NZ_CP044548.2	2908175-2908189	0	1.0
NZ_CP044548_4	4.2|784716|15|NZ_CP044548|CRISPRCasFinder	784716-784730	15	NZ_CP044548.2	2877252-2877266	0	1.0
NZ_CP044548_12	12.1|2499282|39|NZ_CP044548|CRISPRCasFinder	2499282-2499320	39	NZ_CP044548.2	292681-292719	0	1.0
NZ_CP044548_3	3.1|770368|39|NZ_CP044548|CRISPRCasFinder	770368-770406	39	NZ_CP044548.2	3236327-3236365	1	0.974
NZ_CP044548_9	9.1|1386064|39|NZ_CP044548|CRISPRCasFinder	1386064-1386102	39	NZ_CP044548.2	2067290-2067328	1	0.974
NZ_CP044548_13	13.1|2717579|39|NZ_CP044548|CRISPRCasFinder	2717579-2717617	39	NZ_CP044548.2	1459592-1459630	1	0.974
NZ_CP044548_12	12.1|2499282|39|NZ_CP044548|CRISPRCasFinder	2499282-2499320	39	NZ_CP044548.2	3236327-3236365	2	0.949

1. spacer 4.2|784716|15|NZ_CP044548|CRISPRCasFinder matches to position: 2908175-2908189, mismatch: 0, identity: 1.0

cagcggcgacgagga	CRISPR spacer
cagcggcgacgagga	Protospacer
***************

2. spacer 4.2|784716|15|NZ_CP044548|CRISPRCasFinder matches to position: 2877252-2877266, mismatch: 0, identity: 1.0

cagcggcgacgagga	CRISPR spacer
cagcggcgacgagga	Protospacer
***************

3. spacer 12.1|2499282|39|NZ_CP044548|CRISPRCasFinder matches to position: 292681-292719, mismatch: 0, identity: 1.0

cgacctcgggaaagaaatgttcttgcccgaggtcgaatg	CRISPR spacer
cgacctcgggaaagaaatgttcttgcccgaggtcgaatg	Protospacer
***************************************

4. spacer 3.1|770368|39|NZ_CP044548|CRISPRCasFinder matches to position: 3236327-3236365, mismatch: 1, identity: 0.974

catgcgacctcgggaaggaacatttctttcccgaggtcg	CRISPR spacer
cattcgacctcgggaaggaacatttctttcccgaggtcg	Protospacer
*** ***********************************

5. spacer 9.1|1386064|39|NZ_CP044548|CRISPRCasFinder matches to position: 2067290-2067328, mismatch: 1, identity: 0.974

cgacctcgggcaagaacatttctttcccgaggtcgcatg	CRISPR spacer
cgacctcgggcaagaacatttccttcccgaggtcgcatg	Protospacer
**********************.****************

6. spacer 13.1|2717579|39|NZ_CP044548|CRISPRCasFinder matches to position: 1459592-1459630, mismatch: 1, identity: 0.974

cgacctcgggaaagaacatgtccttcccgaggtcgaatg	CRISPR spacer
cgacctcgggaaagaacatttccttcccgaggtcgaatg	Protospacer
******************* *******************

7. spacer 12.1|2499282|39|NZ_CP044548|CRISPRCasFinder matches to position: 3236327-3236365, mismatch: 2, identity: 0.949

cgacctcgggaaagaaatgttcttgcccgaggtcgaatg	CRISPR spacer
cgacctcgggaaagaaatgttccttcccgaggtcgaatg	Protospacer
**********************.* **************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP044548_6	6.1|935638|27|NZ_CP044548|CRISPRCasFinder	935638-935664	27	MK511012	Pseudomonas phage BR153, partial genome	13931-13957	5	0.815
NZ_CP044548_6	6.1|935638|27|NZ_CP044548|CRISPRCasFinder	935638-935664	27	JX403939	Pseudomonas phage YMC/01/01/P52_PAE_BP, complete genome	29186-29212	6	0.778
NZ_CP044548_6	6.1|935638|27|NZ_CP044548|CRISPRCasFinder	935638-935664	27	MN585195	Pseudomonas phage AUS531phi, complete genome	31795-31821	6	0.778
NZ_CP044548_6	6.1|935638|27|NZ_CP044548|CRISPRCasFinder	935638-935664	27	KU310943	Pseudomonas phage YMC11/07/P54_PAE_BP, complete genome	44485-44511	6	0.778
NZ_CP044548_6	6.1|935638|27|NZ_CP044548|CRISPRCasFinder	935638-935664	27	AF165214	Bacteriophage D3, complete genome	38246-38272	6	0.778
NZ_CP044548_6	6.1|935638|27|NZ_CP044548|CRISPRCasFinder	935638-935664	27	NC_016762	Pseudomonas phage phi297, complete genome	12442-12468	6	0.778

1. spacer 6.1|935638|27|NZ_CP044548|CRISPRCasFinder matches to MK511012 (Pseudomonas phage BR153, partial genome) position: , mismatch: 5, identity: 0.815

gagcgaacggggcaggtggtctcgagg	CRISPR spacer
gagcgaacggggcgggtggtcatgtgt	Protospacer
*************.******* .* * 

2. spacer 6.1|935638|27|NZ_CP044548|CRISPRCasFinder matches to JX403939 (Pseudomonas phage YMC/01/01/P52_PAE_BP, complete genome) position: , mismatch: 6, identity: 0.778

gagcgaacggggcaggtggtctcgagg	CRISPR spacer
gagcgaacggggcgggtggtcataggt	Protospacer
*************.******* ...* 

3. spacer 6.1|935638|27|NZ_CP044548|CRISPRCasFinder matches to MN585195 (Pseudomonas phage AUS531phi, complete genome) position: , mismatch: 6, identity: 0.778

gagcgaacggggcaggtggtctcgagg	CRISPR spacer
gagcgaacggggcgggtggtcataggt	Protospacer
*************.******* ...* 

4. spacer 6.1|935638|27|NZ_CP044548|CRISPRCasFinder matches to KU310943 (Pseudomonas phage YMC11/07/P54_PAE_BP, complete genome) position: , mismatch: 6, identity: 0.778

gagcgaacggggcaggtggtctcgagg	CRISPR spacer
gagcgaacggggcgggtggtcataggt	Protospacer
*************.******* ...* 

5. spacer 6.1|935638|27|NZ_CP044548|CRISPRCasFinder matches to AF165214 (Bacteriophage D3, complete genome) position: , mismatch: 6, identity: 0.778

gagcgaacggggcaggtggtctcgagg	CRISPR spacer
gagcgaacggggcgggtggtcataggt	Protospacer
*************.******* ...* 

6. spacer 6.1|935638|27|NZ_CP044548|CRISPRCasFinder matches to NC_016762 (Pseudomonas phage phi297, complete genome) position: , mismatch: 6, identity: 0.778

gagcgaacggggcaggtggtctcgagg	CRISPR spacer
gagcgaacggggcgggtggtcataggt	Protospacer
*************.******* ...* 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	153090 : 167446	19	Mycobacterium_phage(46.15%)	portal,capsid,tail	NA
DBSCAN-SWA_2	186378 : 195984	9	Planktothrix_phage(16.67%)	protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP044548|153090:167446|DBSCAN-SWA
ATCAGGCGGTCCTTCCCAGCGCGGCAGCGCCGGTCGAGAGGTCGGAGTAGACGTCCTCGGCGATGCCCTCGATGTAGGCCCGGCCGTCACGGAGCTTCAGCTCGCCGGTGACGAGCAGGCGACCGGGGCCGTCGCTAGCGGCCAGGCGCATCGACTGCCGGTGGGGCATGACGCGCTCGCCGCCCCGGAACCACAGCAGCTCGGGTCCGCGCTCGCCGACCCAGGCAGGACCGGAGGCAGCGCTTCGGGTACCGCGGGCGTAGCCGCCGGCGCGGTTGTAGGCGTTGGACAGCGACCCGTATGTCGCGATCGCGTACCGGAAGGACGCCAGGATGTTCGACAGCGGGTCGTAGATGTCCCGGTCGTAGCCCTTCATCGCGTAGGCGCGGAAGGTGCTGCCGATGACCTGCATCAGGCCCTTGGACGGGTCGCCGCGCTTGGCGTTGATGTCCCAGTTGTTGATCGCCCGCGGGTTGCCACCGGACTCCTGCATCATGCGGCGCAGGACCGTGCCCACCAGCAACGGCGACTGCCCAGTCATGAAGAGCGCCTTGCGGACCGTCGTCCGCCAGCGATCCACGCCGCCACCAGGGGCGCCGCCGGGCATGTCGCCCGTGTCGCTCGAGCCGAACATGCTGCGGGCCTTCTCCGCGATGACGCCCGTGATCTTGCGCATCGCGCCGACCCCAGCCTGGGTCCAGAAGTCACCCGGGGCCTTCGACAGCAGCGCGTTGAGCGCGGACTTGCCCTGGTCGATGACCTTCCCGGCGAGACCGCCGAGGATGCCGCCGCCACCCGGGAGACCGCCACCCTGACCGTTGCCGATGTCGACGTGAAGGTGATCGAAGTGGTTCGCCGCCCGCCAGATCGTGTTCCAGCCGTCCCGGCGCAGCATCGCGTTGAGCTTGTCCAGCGCCGCCATCTCGTTGCTGAACTTGGAGTTGAACGGGTCAGCGTTGACGTCCAGCGCACCGGCCTTGTAGTGCCAGCCCGTCGCGGAATGGGCGCCCGGGGCGACCCCGCCGAAGGCGGGGTGCTCCGAGACGTGGTAGCCCATGCCCTGCAGTCGCTTGCCGAGAGCGACGATGCCGCCGCTGGCGTACCCACCACCCATGAACTTCGCGAAGGGAACGCCTCGCTTGGCCGCCTCGTTCGCGGCAAGGAACATCGACCGCGAGTGGTGGTCGCGCAGACCCTCGGAGACGAGGACGCCCTCACCGGAGCGCATCGGGGTGAGCTGGTCGTCACCGCGGTGCATGGGGGTGTAGCCGGGCAGGATGCCGCCGCGAGCGCGGCCACCGGGGCGGCCACCGGTGTAGAAGCCGCCGGCGTCGTAGCGGCCCTTGCCGCCCTTGCCGCCGTTCGGGTTCGACCCCAGCGTCGGGATCTTCTTCGCCAGGTCACCCGCGCCGATAGCGTTCAGGACCGAGCGTACCTTCGACAGGAAGTTGTTCTCGATCCAGCCGAGAGCGATGCCGATCGGACGCGAGATGGTGGAGGTCAGCCCAGACCAGATCCGCCCGATGCCGTCCTTCGCCGTCTTGAACGCATCCTTGACCTTGCCGATCCCGGTGCGCATGTTGTCGAAGGCGCTCTTCGCCTTCTTCCACAGCCACGACGCCTTGTCGCCGATGACCTGAAAGGCGCCGCGTACGGCGGGTACGCCGGTGTTCTTGATCCACCCGAAGACCGACTTGACCCGGTTGAGGATGAACGTGAAGTAACGCTTGTAGACGTTCGTCCACAGCCAGGAGACGACCTTGCCGATCGCGCCGATAGCGGTACGCACCCACGGCAGGCCGGTGCTGCGGATCCAGCCGAACACGCTGGCCGCGATGCTCTTGATCTTCGAGAACGCGGGCCGGATGTGGTTGGTCCACAGTCGCGACGCAGCGGCGCCGATCTTCGTCAGCGCGTCGCGCATCCACGGCAGGGCGGTGTTGCGGAACCAGGCGACGACCCTGCCGACGGCGACCTTGATCGAGGCCCACAGCTTGTTGATGAAGTTGCGGAACGTCGCGTTCTTCTTGTATAGCAGGACCAGTCCGGCGACGAGCGCCGTGATCGCGAGGATGACCTTCCCGATCGGCGACATGTTCATCACCGCGTTGAGAGCACGCTGGGCGACGGTCTGCGCCTTCGTGAAGAAGAGCCGGGTCTTGGCGAACGCCAGCCCGGCCTTCTCCGCGACGGTGCGCGCCTTGACGGCACCGGTACCACCATTGACGGTCGCGGTGTAGACCCGCTGCGCCGCGGCGTAGGAGTACGTCCCAGCTTTCCAGGCGGCTTGGGCGGCGTGGAAGGCCTTCTCGACGCCGTGGTAGATCTTCTTGGCGACTCCGGCGGCCTTCGTGGCGGCGGTCGCGACGTTGGTCGCGGTCGTGTACGCGACCATCCCGACCCGGTACGTCGCGTACGCGCCGGCGAGGCCGAGCACGACCTGCTTGTGGTCGACGAGGAACCCGGCCGCACTCTTGAGCTTGTCGGCGAGGCTGGAGACCACGTCCCGCGCCTCGCCGCCCGCGCCGGTCCCGGCCTTCCACTCGTCGACGAAGCCCTGGACCGCGGGCACGACCGTGTCGTTGAGAACCTTGCCGCCGTCGGTCAGGACGGGCAGCAGCCCTTCGCCGAGGCTGGCCTTGACGTTGTCGAGCTGGGCCTTGAGACGCTGCTGCTGGCCGGCCGCGGTCTCGGACTCACGCCCGAACGCACCCTGCGCGTCGGTGGTCTGCTTCTGGATCAGCGAGAGGGCCGCCTGGGCCTTCTCCTGGTCCGTGAGCTGGGTCTTCTTGCCCTCCATCGCCTTCGAGAGGCGGGAGTTCGCACCGGCCAGCGCGGCCTCGGCGCGGAGATACTCGTTGGAGCCCTTGCCGTGCTCGCGGAGCGCCTCGTTGTAGTCGCGCTGGGCGAGGATGGCCTTGTTCTGGGCGACCTTGATCGCCTCGGTGTCCTTCGTCCGCTTGACGATGCCGGTGGAGTAGGCCTCCGCCTCGAGCATCGTCGCGTTGAGCGAGACGCCGTACCGCTCGATCGGGTCGGTCTCGCCGCGCATCGCAGAGGCCAGCGCCTCAGCAGCCTGCTTCGTCGGCCCGCCGAACTGCGCGCTCAGGTCAGAAGACAGGCCGAGCAGGTTTCGCGTTTGGTCGGCGTAGTCCTTGATCCCCTTGTTCTTCAGCCCGGCGCCGAGGGTGGATGCGAGCTCGTTGTACTCGTTCCGCGAGAGGCCGAGGTTTTGGGCGGCGCCCTTGCTCGCCTTGTCCATCTCGCCGAAGGACTTCTTGAAGACCGCCTCGAGCCCGCCGGTCGACTGCTCCAGGTCGGAGGCCTCGGAGACGATCGAGCGGATGCCCTGCGCGACCCCGGCGGCGCCGATGCCGGCGAGGAGCCCCTTGCCGAAGACGCCGCCGGCGCTCTTGCCGGTCTTCGCGGCGTCCTTGCCCGCGCCGTCGAGCTCGCGGTCGATGTCGCGGCGCATGCCCTTGGTCGACGCGACGATCGAGATGTACGCGGTCGCGAGCTCCAGCGCGGGGGCGTCAGCCATACGACGTCCTCCTTCGGGCATGCGAAAGGCCCCGCCGGTGACGGGGCCTTGAGGTGGGAGAGAGCGGGTGGTCAGCCGTCGATCTCGCGACCCCACTGAAGGAAGTCGGCGAGCTCGTCGAGCGGGATCGCGTCCGAGCCGAACTGCTGGGTCTCGGCGGACCGCGAGGTGTCCTCGACACCCGGCCGCTTGACCAGCCGTGGCCGGTTCCGGTTCTTGCGGCCGTCCTCGGTCTTCGACCACTGGAGCCAGTTGACGACGTCGAGGATGGCTGCGAGCAGCTGCTCGGAGAGACCCCATGCGGCCTCGGCGACGTCGTCGGGAAATGCGGCGGCCCAGACGGCTGCGTCCTTCGGGAGGTAGGCGACCGCGGAGGCGTATTCGAGGAGGGTGAGGCGCTCTCTGGCCTCGCGAGGGGTGAGGTTGTAGGTACGGAGCAGGTCGGCGGTCAGTGGCTCTCGGTGGCTTGCCAGGAGCCACGAGAGCCGCGTCAGTTTGGGGCGGCCGCTCCGAGCATGTCCGAGACGAGCTCGGCTCCGGCCTCGATCGAGACGCGCCCGGTGTCCTCGTCGCGCGCCAGGTCGAGGGCCTGCGCGTACTGGTCCTTGCCGACGAGCCGACGCAGCACGCCCGGCAGCTTGGTGGCGTCGCCGTCCTCGAGGGCGCTCAGGTCGTCGAGGAGCTCGAAGTCGTCGAAGGCGTCGGCCTCGATCGTGAACTTCTCGCCGCGGACCTCGACGACGCGCTTGCCGTCCTCGGTCTCGGTCTTCGGCTTGTGGTCCTGCGGCTTCTTCGCGCCGGCCGGGACGGTCTTCGTGTCAGACATGCGGGGTGCCTCTCGTTCGTTCGGGGGAGCCCTGGTGAAGCCCCGACCCCGGCGTGGGCTCCCCGCGATGAAAGAACGCCGGGGCCGGGGGTCTGGGGGAGGTCAGGCGGTGGTGACGCCGTTGTCGGTGAAGATGTAGGCCTTCACGCCGTTCGCGTCGGGCATGGCCTGCGCGGTGACCTCGTAGCGGACGACGTCCGAGTGGACGAACGTCGCGTCGCTGGTCTCGGTGATCTGGAGGTTCGGCACGACGATGCGCAGGCGGGCCGCGCCGTCGCGCATCTCGAAGACGTACGCCCGCTCGGGCAGGGCGTCGCCCTTGACCTGGATCGCCTGGAGGGTGCCCTTGGTCGAGGACGCGGCGGTGGTGGTGACGTTGGCCGCGCCGTAGACCTCCTTGAGCACGTCGGCGTTGGTCTCGAGGAAGGACCACGAGAAGGTGACGTCGTGCTCGGTCTGCAGGGTGCGGACGGTGTCGCCGCCCCAGGCCTTGATGGTCTCGACGGAGCGCTCGGTCGACATGGTGACGCCGTCCTCGCCGACATAGCCGGTCGCCTTGAACGCCGGGGGGAGCGCGGTGGACGAGTCGGTCGGGAGTGGGGTGGTGCCGGTGGGGGCGACGAGGACGCCGCCCGTGCCGGTCAGCGGGGCGCCGGCGAGGATGTCTGCCTTGGCCATTGCGGCCTCCTTCGGGTTCTGCGGGGAGCCCGGAAGGTCGACGGCGTGCCCGGCCGTCAGCGGGTGGTCTGGAGGACTACGCGTCCTTGGGGAGCTCGGTCAGGCGCCAGCCCGACTTCTGCCATGCCTTCGCCTGGTCAGTCGGCACCTCGTGCGACACGTCGGGGAAGACGGGGTGGTAGACGCGGCGGGTGGTCGGCTTTGCCTCGTCGGCGGCCTTGGCGGCGGCAGGGGTCTTGTCGCTCATGCGAGGGGCTCCATTCGGGAGTAGACGGTGGCGACGAACTGGAAGCGGAAGCGCCCGGGCCGTCCGACGTCCGGGTGGTTGACCGGCAGCTGGGCGAGCACCTTGCGGAAGGTCATCCCGTGCAGCTGGCCCTGGGTCTCGGAGAGGTGCGCGTGGGCGCGGCCGGCGAGCCCGAACGCGTCGCCCTCGTCGTCGGCCCAGCACTCGACGAGCACTCGCGGCTCGACGAGCACGAGGTGGCGCGGGGCCTGCCCGCCGACGGCGGAGACCCTGACGACCAGGGGAGGCTCGGGCGACGAGGACGGGTATCGGGTGCCGACCCGTGCGTCGGGCAGGGCGTCGCGGAGAACGCCGACGACGCCGACCTCGACGTCCGGCGGCGCGAGCAGCTCGGTCATCAGCTGCCCCCGAGCGCGCGGATCATCGCGTTGGACCGGCTGTTCGCCTCGCGGGCGTCACGGGTGACGGCGATGACGGCGGACCGGGCGCGGGTGTGCGGGTTCTCGGTCTGCCGCGCGACGTGCCCGTCACCGGCTGCCTCGGCGACGCGCTCGGCATGGCCGTGCACGAGCGCCTGAACGGCGGGGGAGGTGAGGAGCTCGGAGTAGGCGCGAGAGTGGTGGACGACGCGTGCCATGGCTCTCCTCTCCCCTCAGCCCGTGGTGCGTCGCAGGTTGACCTGCACGCCCGGCTCGTAGTCGAAGGGGCCGTGCGCGAAGTCCTCGACCGGGCCCGTCACGTCGAAGGCGCCGAAGCCGGGGAGGACGACACGGTCGTTCGGGCCGGGTCGGAAGGTCGTGGGCGCGAGGACGACGGCGTCGACGTCGGTGCGCTCGTGGCCGGCCACTCCCGGCTCGGAAGGGTTGCCGGTGTACCACCCGAAGACGAGCACCTCGACGGGGTCGGCCCACGTCTCGACGTCGTTGCCGCGGGGGTCGGTCGTCGTGCCGGAGTAGACCTCGTGGCCGATCGGGCGTGCGGCTCTCACGGCGTGGTCTCTCCGGTCTCGAAGATCGGTCCGCGGCCGCCGTTGAGGACGGAGCCGCACGAGCACGGCGCGCCCCAGTGGACGGAGCAGGTCGCCGAGTGGATCGCCTGTCGGCCGGGGGCGGTGTCGACCCCGAACGCCTTGCGCCCCTGCCGACCCGCGAAGGTCGAGCAGAGGTCCTGGAGCTGGCGGATCTCGGAGGGCCAGAACATCGCCCGGCGCTGGACGCGGGTGTCGAAGGACTCCGAGTGGCCGAACGGGCCTGCGGACTCCTGGCGCTGGCTCAGGACGCCCGACCCGGCCTCGTGCCACCGGAGAACGGCCCCGCGAAGGACCGCCTTGACGGCCTTCGACCGGGTGTCGTCCTCGGCGAACTGAGGGCTGGAGAGGCAGGGGGCGGCCGTGGCTGCCATGGCCTCGGCGTCCTCGATCATCGCCGCGGCCTTCGCCGCGTCGATGTCCGCGAACGGGACGAGGTCGTCGGGTGTCAGGTACACGTCGCCCCCTGCCTTCTTCAGTTGTCCTCGGAGCCGTCGGCGTCCCCGGAGGGAGCCGCAGCTGCCTTCTTGGCCGCGCGCTTGGGCGTCGGCTTCGAGGTGCTCTCGAGGTCCGTCCACGAGCCGACGAGTCGTGCCGCCGTCTCGGTGTCGACGTTGACGACGACCCCGTTCGCCTCGTTGCGGAGGCGCGGCATCAGGCGACCTTGTCCTCGATCACCGCGAACTGGTCGGCGTCGACGTACCAGGCGTAGATGATCTCGGTGCGGAGGACGACCTCGTTGTGGCCCTGAAGGTCGCGGCCGGTGTTGTCCGGGTCGCCATACTCGATCACCTTGAACGGCAGCGAGCGCTGGACGCCCCACTTCACGCCGCCCTGGAAGTTGCCGACGATCGCGCGGACCTTGTTGTCGGCCGACGAGCCGTCGACCGGCTTGCCCGAGACGGTGCTGGAGACCGCGGCGTTGACGCCCTCGAAGGAGGTGACGTTGCTGCCGAGGCCGAGCTCCGGGTACTTCTTCCGGCCGTCCGCGTAGCGGGCGGTGGACAGGGTCCAGGCGTGGGTCGGGTCGAAGGCGACGCCGTTGACGGAGTAGCCGTCGCCGATGACGAGACCGGCCGCGGCCTCGAAGTCCATGTCGGCGTCCGCCCCGACCTCGACGCGCTTGGTCGTCGAGTTGAGGTAGTTCGTCCAGGCGGTGATCTCGTTGCCCGTCCGCGGGTTGATGCGGAAGTACAGGCCGAGGTCGAGAGCACGGGAGAGAGCGCGGCTGCACTTCTCTTCGTACTTTGCCATGATGCCGAGCTGGTACTCCTCGTCGGCGTAGACGAACTCGTCGGAGGTGCGAAGCTGGACGACGGCCTTGTGCGGGACGGCGAGGACCGTGGACGGCTTGGCCTCGTCGCTCGACTTGGAGCCGGACTCCTCGACGAACTCCGCGGTCAGGTCGTCGTCGAAGGTGACCATGGTGGTCGCGCCGAAGCGCTGCGGCACCTGGCCGGAGAGGGCGGCGACGGTGGAGCCGGTCTTGGCTCGCTCGATGATCCCGGCCTCGATGTTCGAGGGGAGCACCGTGTCGGTGGTCTTGACGGTCATGACGTTCTCCTAAGAGGTGGGTTGAGCGCCCTAGCCCTTGTTCAGGACGGTGCGAAGGAAGTCCCTCGTCGGGTCGGGCGGGGAAGCGGGGTTGGTCCCCTCGCCGGGGACCGGGTTCGTGCGACGGGGCTGCGACGTCCGTGCGACCAGCGCCTCGGCCTGAGCGGTCAGGGAGGCCTCGTCCGAGCCGGTGAGGAAGAGCTCGGCGTCCTCGTCGGTCAGGCCGTGCCGGGCCTGGACCCGTGCTCTGGTGGCCTCGTGCCGGGAGGTCGTCAGCTCGGTCTCGAGCTCGTCGACCCGTGCGGCCTTCGTGCGAAGGTCGTCGTAGTCGGCGAACTTCGAGCGCTCGCGGCTCAGGCGGTCGCTGACGACGCGGTCGAGCTCGGCCTGCGTGAAGGTCTTTGGCTGCTCCTCGACCACGGAGGTCTCGTCAGCTGCCTCGGGGGCCTCGACCTGGGCCTCGGTGGACTCGTTGGCGTCGGTGCCAGGGTTGCCGCTCATCGCGTGCTCTCTCTTCCGTGTGTAAAGCCCCGGTTTGAGCGCACCGGTAAACGCGACCCCGCTGAGCGGGTAAGTCTTAGCTTCGCTCGAAGGACTCGAGGTACTTGGCGGCCGCACGAAGGCGGTCGGGGTCGTCCCTGAAACGACCTAGGCCGTTGTTGCAACGACCGCAAATCAGTCCACGAATGCACTGCTGGCACCCGAACCTTCCGGGGCAGTGCTTGTGGTCATGGTCGATAGCAAGACGGCGAGGGCGACCCGTGTGATGGTCGATAGCAGTTTCAGGCTCTCTGCAAATAGCGCATAGACCCTGTTGACTTGCTGCCAACAGCTCGTACTCGCCAAGCACCAATCCGTGCTGATAGCCGGGATAAGGGTTGTCTGGCCTGGCGTTTCGGGTCGGACTCGTGGCTCTCCGCGCCGCAGACCGTTGCAGTTCGCTAGCTCGGTAGGCAGGATCGGTGTACCGAGCGGAGTTGTAGAGGGAGACGCACTCCCGGCACCGAGAGTTGCGGCCGTCTTGGGAAGCGCGGTTCTTACAGAAACCCTCGAGAGGTTTGAGTTCGCCGCACTTGTTGCAGCTCTTGGTCTGGACGGTAATGTCGCTCATGGCGATGCCTCCACATCGTCAGCCCGTCAGGAGGTGCAACTCCTGGCGGGCACTTCTAGTTCTTGTTAATCTGCCGCGTTCTTCAGGTAGTCGTAAACGCGCTGATTTTCTTGCCGCTTGCGATCTTCAGACCAGTTCGCTTTTCGCTCGCTGTACTTGAAGGGCACCCCGATGACCTTCGTGACGTTCGAGGCGAACTCGGGCTTCGCGGTGCAGTGGCAGTTGTCGTGGCTCTTGAACTCGACCGACGACTCGCTGTAGACGCCGCCGCGACCGGCGAGCATCCGGCAGAAGCCGCACGCCCCCGCTCGGGTCGCCCGCCTCCATCCGCTGGCCGCGGGGTCGGCGACCGACGACTCGACGACGGTCAGCCGGTGCTGGTCGGCGATCGAGCGCTGCAGCCCGCCGGACACGAGCGACAGCGCCGCGGCAGTGTCGGGCTCGGCGGCGAACAGCGGGTCGACGCCCCAGCGGGCGAGCGCCTCCCACCGGGCGGGCGGCAGGTCCTGGGGCACGACCGGCTCGAACCGGCCCTTGGCCTCGGCGCGCTCGCGCTCCGTGTCGTAGTACTCGGCGGCGAGGGCGGCGGCGGCGGCGCCGTAGCGATCGCCGAGCGCGGGCAGCACCTCGATGAGGGCGTCACGGACCTCGACCGCGTCGGCCGCGGACATCCGGTCCCACACGGCACCGAGGTCGTCCAGGGCGGCCTTCGTGAGCTCCTGGAGCGCGTCGCGCTGCCTGGCTACCGGCACTACTTCTCCTCGAGACCGGCCGCGTCCGCCTCAGGGAGACGGAGCGACACCGGGGTGGCACCGGTGAACTCGATCCCGGGCAGGCCGAGGCGTGCCGCGGCGTCGTTCGGGCTGACGCCCGATCTGATGGCCGCGCCGAGGGCGTCGAAGCGAGCCTTGAGCTCGGCGGCCGTCTCGGCCTCCTTGGACGGCGCGAGCGTCTCAACGAGCGACCGGCCAGCGGCGAGCTTGCGCTCGCCCTTGAACCGGCGAATCTGGTCGGGCGTGAGGCCCATCAGCTCGAGGCCGACGTCGGTCTCGGCAAGGCCGGGCACCGCCGCGACGACCTTCGTCCCGGCGTCGGCGACCTGGGCGCGGCTCTCGAAGCGCGGGTTGCGCCACTGCGTCGAGATCGAGGACCAGGCGGCGGGTGCCTCGTCAAGGTCGTTCTGCATCAGCAGGCCGCGGCGGATCGCGCGCTGGATCGGACGGTCGAAGTCGTCGACCGCGCCCTCCGCCTCGGCGACGAGCTCGTACTGAGACGCGTCGTACGCGCCCTCGGAGGTCGGGTTGGCCATGTCGGTGATCGCCACGGCGGAGTCGGGGAGCGACGCCTCACGGGCGAACATCTTCGCCAAGGCATTGAGCTGGGCGAGGTGCGGCTCGGGGCTGGCGGCCGGGAACTGGAGCACCTCGGCCCGCGCGAGCGACGGGTCCGTCTGCTCCTCGTCGTCGGGGATGCCCTTGACCCGCCCGAGCATGGCCTGCCAGGCCGCGAGGGTGTTGCCGTCCTCGTCCTGGAAGGCCCCGCCGTCGGCTCCGAGGATGACCATCTCGGGCCAGGAGTAGACGTCCATGTGGCCCTCGGTGCGGATGAGCGCACGGACGGCGGCGTCCTGCAGGCCCATGATCGGCCGCGAGATGCGGGAGTACCCGAACGGGCGGCCCTGCGGCTTGTAGATCAGCGGCTCGACCGGGACGCCGTAGACGTGCTCGTGGCGGTCGGTAGCGACCCAGCGCCCGTCGACCTTCAAGACCGGGATCGTCAGGCCGTCGAGGTACAGGACGAAGCCGGTGACCTTGTCCTTCTCGCGCTCGGTGACCGACAGGAAGGAGTCGAGCCGCCGCGTGCGGCTGTTCCACCGGCCGGTGCCGTTGAGCGCGTCCTTGGCGTGAAGCAGCGCCTTCGGCTCGCCGTCGCCGCCGGTGGTCCCGACGAGGAAGGAGACGCCGTGGGTGAAGGCCTTGACCCGTGCGCCGGAGAGCTCCGACAGCAGCATGTTGTCGTCGGCGAACTCGCGGAGGCCGAGCGAGTCGAGGTCGCCCTCCGCCCAGGTGAAGCCGTCGAGGTGGCAGCGCCGGGCGAGCGCGTCGACCGACTTCGCTGCCCAGCCGAGCACGAGCCCGAGGTTGTCGTAGTGGCCCGGCATGACGGCGCTGAGCTGACGCAGTGCGCGCTTGCCGTCGTAGTAGTCGGACCGGACGCGGTTCCGCGGGGCCCGGGCGTCGAGCTGGGCGAGAAGGGCGTTGGCGAGCCGGTTCTCGTCGTCCGAGAGGCCGCTGACCCTGACGGGCTCGACGGTCATCAGGGCCTCCTATCGGCGGGTGGAGTGGCGCCGCGACCCGGCTCGTCGGGAGCCGCGGGACGACGGGGCGCCGGGCTCGGACGCGAGCACGCGGGCGGCGCCGGGCTTGGTCGGCCGGTCGGCGACGGCGCCGACGAGGGCGTACGTGGCGGCTTGGATGGGCGTGACGTCGGAGTCGGCGGACCGTCGGTTCCAGACCCACATGCCGGTGTCGCCGAGGGGCCGCTTGCCGACGGCCAGGGCCGCGGCGGTCAGCTGGGGCTGGTCGATGTGGTGGACGTCACCGGTGACGACTCCTGAAAGGAGAGCCGCGCACCCGGCGCCGAGCTCCTTGACCTTCAGGGCGTGAACGGCGACGCCGGGCCGGTCGCCCGCGCCGTCGCGCTTCAGGAACCACCTCGGCCCGCGCTGGATGAGCAGCGCGCTGACGGGGGAGGCGACGTCGACGACGACGGCTCTGATCTCAGGGTTCGCGGACAGGAGCTGCTCGACGAGCGGGACGACCCACCCGACGCCACGGCCCTTCGTGTTTTGGTCGGCGACGAGCTCGACGTGCCAGGCGCCGTCGGCTCGCTGGCCGGCGACGGAGACGGAGGCCCAGGCGAGGTCGGGTCCGACCTCGACCCCGAGGGCGAGACGGTCGACGGCGCGCGAGTGCTCGTCGGCCGCGTCTTCCCAGGCGAGCGTCGGCACGACCCCGCGGGACGCGGCGGACGCCCACACGCCGAGGCGCTCCTGACGGAACTCGTGGTCCGACATCGACGCCCGCTCGGCCAGCACGGCCTCGCGGGGGATCCGGTACGGGTAGGCGGGGTTCGCCTTGCGCCAGGTGTCCTCGTCGTCAAGGTCGTCCTCGGCCTCGGCGGACCACTCCAGCCAGGCCGTGCCCTCGACGGGCTCGCCGGCCGCGCCGCGCATGCCGGCAGCTCGGATCTTGGCGAAGACAGCCCCGGCCCCGGCGGTGTCCGAGGGCGGGGTCCCGAGCACGAGCACCTGAGGGTTCGGCCGCGCCGAGAGCGTCGGCAGCAGCGCCGCCCAGGAGTCGGCGGTGAGGATCTGGCCCTCGTCGCAGATGACGAGGTCGGCCGAGAAGCCGCGCATGCCCTGCGTGGAGCGAGCCTTGAGCAGAACCTGCTGGCCGGTCTTGAAGCGGATGACCTCGCGCCCGGGAGCCTGGTTGACCTTGTCGACCCGGGCCTTGAGCGACGGGTTGTCCTCGACGACGTCGATCAGGCGTTGAAAGACCTGCTTCGCGGTGTCGGTCGCTTGCGCCGAGAGGACGACGAGCTGCTCGTCGAAGAGGAGGATCCCGGCGAGGATGCGGGCGACGGCGACCGACGACTTGCCCTGCTGCCGTGCGACCGAGAGGCCGAACGTCCGGGCGGCCCAGTCGCCGTTCTCCTTCTCGCCGAGCATGACCTCGAGCGCCTCGACCTGCCAGGGGTCGAGATGCAGGCCAAGCCCGGCGCAGAGGTCGACCACCTCGGGGGTCGAGTTCTCGACGGAGGGGGGCGCGTAGCGAACTCGCGGGGGAGCGCAGGCGATCGCGCCCGGCTCAAGAAGCGGCGCCACGCCGCTTCCGTCGTCGGGTGGCGACCTCGTCGATCGGGTCCGCTGCGGGGGCGGCGGGGTCGAGGATCTCGATCCGGCCGAGGACGTCGGACAGGCGCAGGTAGAGCGCTGCGCGGTCTCGCATGGACTCGCAGGTCTCGAGGTCTCGGACGATCGCGTCTCGGACCGCCTTCAGCGCCTCCACGGTCGTCCCTGAGGCCACGACGGACAGGTCCATGTCGCCTCCTGCCGGGCCCGCGGAGGGCTTCGCTATACAAGTTGTCCTGTGGCGTAGGGACCCTCACGCACAAATGGGCTACGCCGAGAATGGTTCCGGGAGCACGAACGGGGGGATTCGCCCCCTGGGGCGCTTCAGCTTCGCAACGATCCCGAGGATCGGATGACGGGCGCGACGCGGCGTCGTCCCTTCGCGCGGTTGCACTTCACGCCGCAGGTCTCGCACTCGGCGAAGTGGTGCGCCGGCCGCATGTTGTGCGGCTCGTCCTCGCCGTCGAGGTAGAGGGGCACGACGTGGTCCATGCAGTCGGCGCCGGGGTGGCCGCAGAGATGGCAGATGCCGCTCGACGCCGCGAGCAGCGCCTTGTTGCGCTGCCGGGTCTGATGGGACGTGCCGCGCGGTGTCGCCATGCTTCGCCTCGCTGACGCATTTCGAGATGGGCGTGCCGTCCGAAGAACACCCTGTCGCGGTTCCGCGACGTCGGGAGCCCCCCCTACGCCGAGATCTTCCGCGTCTTCCGGTCGTGGCGTCGGCGGTCGCGCTCGGCGGCCAGCTCTTGCACGTCGCCGAGGCGGTACAGAGGTCGCTGCCGGCCGAGCACCAGGCGGGTCGTGCCGTGCCGCAGGAGTCGGCCCTCGTCCTGCCAGCGGAGGACCTCTTTCGCAGTCACGGGCTCAGGCCCGAGCCAGTCCGACGCGTCGGAGAGCCGCTCGATCTCGGCGGCCGTCATCAGGCGGTCGGGGATCTGCTCGAGCATGCGGGCGGTCGTCTCCTCGACCCCGTGCTGCGCCCCGCACAGCCCGCACACGACCGTGGGCTGCCACCGCTCGGCGAAGAGATGGCCGGCGCAGCCGGCGACGTCGCAGGTCCCGACATAGCGGCGCTCGGGCGGCAGGTCGACGGCTCGGGTCGCGTCGGCCACCCACCTCCCGGCGGTCGAGGCGATCGTCTCCGCGTCCTCGTGCGCCCGCAGCGCCGCCGGTCCGAGCTCGCCCCGCAGCTCGACCTCGAGCCAGTCGAGCCCGGCCCGGATCGTCGCCCGTAGCTCGGAGGCGCGGGGGTCGAAGGGCAGCGGCCGCTCCGCGCCGCCTCGCCGTCCGCCGCCGCCGCCCGTCCCGACCCGGGACTGGCGCGAGGCGGTGACGTCGAGCTCGTCGACGAGCCAGCGCAGCGTCACGAGGTCGTCGGCCGCCGAGCGGGCGCAGGTCCAGCAGATCGCGCCGTCGTCCTGGATCGGGCGCGAGCATCGACATTCCGAGCCGCTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP044548|153090:167446|159033_159369_-|WP_123091063.1|DBSCAN-SWA
MRAARPIGHEVYSGTTTDPRGNDVETWADPVEVLVFGWYTGNPSEPGVAGHERTDVDAVVLAPTTFRPGPNDRVVLPGFGAFDVTGPVEDFAHGPFDYEPGVQVNLRRTTG
>NZ_CP044548|153090:167446|156701_157124_-|WP_163562490.1|DBSCAN-SWA
MTRLSWLLASHREPLTADLLRTYNLTPREARERLTLLEYASAVAYLPKDAAVWAAAFPDDVAEAAWGLSEQLLAAILDVVNWLQWSKTEDGRKNRNRPRLVKRPGVEDTSRSAETQQFGSDAIPLDELADFLQWGREIDG
>NZ_CP044548|153090:167446|157558_158134_-|WP_123091066.1|tail|DBSCAN-SWA
MAKADILAGAPLTGTGGVLVAPTGTTPLPTDSSTALPPAFKATGYVGEDGVTMSTERSVETIKAWGGDTVRTLQTEHDVTFSWSFLETNADVLKEVYGAANVTTTAASSTKGTLQAIQVKGDALPERAYVFEMRDGAARLRIVVPNLQITETSDATFVHSDVVRYEVTAQAMPDANGVKAYIFTDNGVTTA
>NZ_CP044548|153090:167446|165945_166179_-|WP_123091054.1|DBSCAN-SWA
MDLSVVASGTTVEALKAVRDAIVRDLETCESMRDRAALYLRLSDVLGRIEILDPAAPAADPIDEVATRRRKRRGAAS
>NZ_CP044548|153090:167446|158778_159018_-|WP_123091064.1|DBSCAN-SWA
MARVVHHSRAYSELLTSPAVQALVHGHAERVAEAAGDGHVARQTENPHTRARSAVIAVTRDAREANSRSNAMIRALGGS
>NZ_CP044548|153090:167446|166672_167446_-|WP_123091052.1|DBSCAN-SWA
MSGSECRCSRPIQDDGAICWTCARSAADDLVTLRWLVDELDVTASRQSRVGTGGGGGRRGGAERPLPFDPRASELRATIRAGLDWLEVELRGELGPAALRAHEDAETIASTAGRWVADATRAVDLPPERRYVGTCDVAGCAGHLFAERWQPTVVCGLCGAQHGVEETTARMLEQIPDRLMTAAEIERLSDASDWLGPEPVTAKEVLRWQDEGRLLRHGTTRLVLGRQRPLYRLGDVQELAAERDRRRHDRKTRKISA
>NZ_CP044548|153090:167446|159365_159866_-|WP_123091062.1|DBSCAN-SWA
MYLTPDDLVPFADIDAAKAAAMIEDAEAMAATAAPCLSSPQFAEDDTRSKAVKAVLRGAVLRWHEAGSGVLSQRQESAGPFGHSESFDTRVQRRAMFWPSEIRQLQDLCSTFAGRQGRKAFGVDTAPGRQAIHSATCSVHWGAPCSCGSVLNGGRGPIFETGETTP
>NZ_CP044548|153090:167446|157120_157456_-|WP_123091067.1|DBSCAN-SWA
MSDTKTVPAGAKKPQDHKPKTETEDGKRVVEVRGEKFTIEADAFDDFELLDDLSALEDGDATKLPGVLRRLVGKDQYAQALDLARDEDTGRVSIEAGAELVSDMLGAAAPN
>NZ_CP044548|153090:167446|158210_158381_-|WP_163562355.1|DBSCAN-SWA
MSDKTPAAAKAADEAKPTTRRVYHPVFPDVSHEVPTDQAKAWQKSGWRLTELPKDA
>NZ_CP044548|153090:167446|166313_166589_-|WP_123091053.1|DBSCAN-SWA
MATPRGTSHQTRQRNKALLAASSGICHLCGHPGADCMDHVVPLYLDGEDEPHNMRPAHHFAECETCGVKCNRAKGRRRVAPVIRSSGSLRS
>NZ_CP044548|153090:167446|162138_162825_-|WP_123091057.1|DBSCAN-SWA
MPVARQRDALQELTKAALDDLGAVWDRMSAADAVEVRDALIEVLPALGDRYGAAAAALAAEYYDTERERAEAKGRFEPVVPQDLPPARWEALARWGVDPLFAAEPDTAAALSLVSGGLQRSIADQHRLTVVESSVADPAASGWRRATRAGACGFCRMLAGRGGVYSESSVEFKSHDNCHCTAKPEFASNVTKVIGVPFKYSERKANWSEDRKRQENQRVYDYLKNAAD
>NZ_CP044548|153090:167446|153090_156351_-|WP_123091533.1|DBSCAN-SWA
MDKASKGAAQNLGLSRNEYNELASTLGAGLKNKGIKDYADQTRNLLGLSSDLSAQFGGPTKQAAEALASAMRGETDPIERYGVSLNATMLEAEAYSTGIVKRTKDTEAIKVAQNKAILAQRDYNEALREHGKGSNEYLRAEAALAGANSRLSKAMEGKKTQLTDQEKAQAALSLIQKQTTDAQGAFGRESETAAGQQQRLKAQLDNVKASLGEGLLPVLTDGGKVLNDTVVPAVQGFVDEWKAGTGAGGEARDVVSSLADKLKSAAGFLVDHKQVVLGLAGAYATYRVGMVAYTTATNVATAATKAAGVAKKIYHGVEKAFHAAQAAWKAGTYSYAAAQRVYTATVNGGTGAVKARTVAEKAGLAFAKTRLFFTKAQTVAQRALNAVMNMSPIGKVILAITALVAGLVLLYKKNATFRNFINKLWASIKVAVGRVVAWFRNTALPWMRDALTKIGAAASRLWTNHIRPAFSKIKSIAASVFGWIRSTGLPWVRTAIGAIGKVVSWLWTNVYKRYFTFILNRVKSVFGWIKNTGVPAVRGAFQVIGDKASWLWKKAKSAFDNMRTGIGKVKDAFKTAKDGIGRIWSGLTSTISRPIGIALGWIENNFLSKVRSVLNAIGAGDLAKKIPTLGSNPNGGKGGKGRYDAGGFYTGGRPGGRARGGILPGYTPMHRGDDQLTPMRSGEGVLVSEGLRDHHSRSMFLAANEAAKRGVPFAKFMGGGYASGGIVALGKRLQGMGYHVSEHPAFGGVAPGAHSATGWHYKAGALDVNADPFNSKFSNEMAALDKLNAMLRRDGWNTIWRAANHFDHLHVDIGNGQGGGLPGGGGILGGLAGKVIDQGKSALNALLSKAPGDFWTQAGVGAMRKITGVIAEKARSMFGSSDTGDMPGGAPGGGVDRWRTTVRKALFMTGQSPLLVGTVLRRMMQESGGNPRAINNWDINAKRGDPSKGLMQVIGSTFRAYAMKGYDRDIYDPLSNILASFRYAIATYGSLSNAYNRAGGYARGTRSAASGPAWVGERGPELLWFRGGERVMPHRQSMRLAASDGPGRLLVTGELKLRDGRAYIEGIAEDVYSDLSTGAAALGRTA
>NZ_CP044548|153090:167446|162824_164390_-|WP_123091056.1|portal|DBSCAN-SWA
MTVEPVRVSGLSDDENRLANALLAQLDARAPRNRVRSDYYDGKRALRQLSAVMPGHYDNLGLVLGWAAKSVDALARRCHLDGFTWAEGDLDSLGLREFADDNMLLSELSGARVKAFTHGVSFLVGTTGGDGEPKALLHAKDALNGTGRWNSRTRRLDSFLSVTEREKDKVTGFVLYLDGLTIPVLKVDGRWVATDRHEHVYGVPVEPLIYKPQGRPFGYSRISRPIMGLQDAAVRALIRTEGHMDVYSWPEMVILGADGGAFQDEDGNTLAAWQAMLGRVKGIPDDEEQTDPSLARAEVLQFPAASPEPHLAQLNALAKMFAREASLPDSAVAITDMANPTSEGAYDASQYELVAEAEGAVDDFDRPIQRAIRRGLLMQNDLDEAPAAWSSISTQWRNPRFESRAQVADAGTKVVAAVPGLAETDVGLELMGLTPDQIRRFKGERKLAAGRSLVETLAPSKEAETAAELKARFDALGAAIRSGVSPNDAAARLGLPGIEFTGATPVSLRLPEADAAGLEEK
>NZ_CP044548|153090:167446|159883_160063_-|WP_123091061.1|DBSCAN-SWA
MPRLRNEANGVVVNVDTETAARLVGSWTDLESTSKPTPKRAAKKAAAAPSGDADGSEDN
>NZ_CP044548|153090:167446|160992_161463_-|WP_123091059.1|DBSCAN-SWA
MSGNPGTDANESTEAQVEAPEAADETSVVEEQPKTFTQAELDRVVSDRLSRERSKFADYDDLRTKAARVDELETELTTSRHEATRARVQARHGLTDEDAELFLTGSDEASLTAQAEALVARTSQPRRTNPVPGEGTNPASPPDPTRDFLRTVLNKG
>NZ_CP044548|153090:167446|164399_165872_-|WP_123091055.1|DBSCAN-SWA
MVDLCAGLGLHLDPWQVEALEVMLGEKENGDWAARTFGLSVARQQGKSSVAVARILAGILLFDEQLVVLSAQATDTAKQVFQRLIDVVEDNPSLKARVDKVNQAPGREVIRFKTGQQVLLKARSTQGMRGFSADLVICDEGQILTADSWAALLPTLSARPNPQVLVLGTPPSDTAGAGAVFAKIRAAGMRGAAGEPVEGTAWLEWSAEAEDDLDDEDTWRKANPAYPYRIPREAVLAERASMSDHEFRQERLGVWASAASRGVVPTLAWEDAADEHSRAVDRLALGVEVGPDLAWASVSVAGQRADGAWHVELVADQNTKGRGVGWVVPLVEQLLSANPEIRAVVVDVASPVSALLIQRGPRWFLKRDGAGDRPGVAVHALKVKELGAGCAALLSGVVTGDVHHIDQPQLTAAALAVGKRPLGDTGMWVWNRRSADSDVTPIQAATYALVGAVADRPTKPGAARVLASEPGAPSSRGSRRAGSRRHSTRR
>NZ_CP044548|153090:167446|158377_158779_-|WP_123091065.1|DBSCAN-SWA
MTELLAPPDVEVGVVGVLRDALPDARVGTRYPSSSPEPPLVVRVSAVGGQAPRHLVLVEPRVLVECWADDEGDAFGLAGRAHAHLSETQGQLHGMTFRKVLAQLPVNHPDVGRPGRFRFQFVATVYSRMEPLA
>NZ_CP044548|153090:167446|160062_160962_-|WP_123091060.1|capsid|DBSCAN-SWA
MTVKTTDTVLPSNIEAGIIERAKTGSTVAALSGQVPQRFGATTMVTFDDDLTAEFVEESGSKSSDEAKPSTVLAVPHKAVVQLRTSDEFVYADEEYQLGIMAKYEEKCSRALSRALDLGLYFRINPRTGNEITAWTNYLNSTTKRVEVGADADMDFEAAAGLVIGDGYSVNGVAFDPTHAWTLSTARYADGRKKYPELGLGSNVTSFEGVNAAVSSTVSGKPVDGSSADNKVRAIVGNFQGGVKWGVQRSLPFKVIEYGDPDNTGRDLQGHNEVVLRTEIIYAWYVDADQFAVIEDKVA
>NZ_CP044548|153090:167446|161539_162073_-|WP_123091058.1|DBSCAN-SWA
MSDITVQTKSCNKCGELKPLEGFCKNRASQDGRNSRCRECVSLYNSARYTDPAYRASELQRSAARRATSPTRNARPDNPYPGYQHGLVLGEYELLAASQQGLCAICREPETAIDHHTGRPRRLAIDHDHKHCPGRFGCQQCIRGLICGRCNNGLGRFRDDPDRLRAAAKYLESFERS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_123091533.1|153090_156351_-	transglycosylase SLT domain-containing protein	Q6VY42	Streptomyces_phage	7.1e-45	50.5
WP_163562490.1|156701_157124_-	DUF5361 domain-containing protein	G8I4C7	Mycobacterium_phage	3.4e-08	30.8
WP_123091067.1|157120_157456_-	hypothetical protein	NA	NA	NA	NA
WP_123091066.1|157558_158134_-|tail	phage tail protein	A0A222ZEQ0	Arthrobacter_phage	6.4e-34	43.2
WP_163562355.1|158210_158381_-	hypothetical protein	NA	NA	NA	NA
WP_123091065.1|158377_158779_-	hypothetical protein	NA	NA	NA	NA
WP_123091064.1|158778_159018_-	hypothetical protein	NA	NA	NA	NA
WP_123091063.1|159033_159369_-	hypothetical protein	A0A068F1K8	Mycobacterium_phage	1.2e-13	37.3
WP_123091062.1|159365_159866_-	hypothetical protein	A0A2D1G803	Mycobacterium_phage	3.9e-27	46.2
WP_123091061.1|159883_160063_-	hypothetical protein	NA	NA	NA	NA
WP_123091060.1|160062_160962_-|capsid	phage major capsid protein	A0A142KAW6	Gordonia_phage	1.5e-130	75.9
WP_123091059.1|160992_161463_-	hypothetical protein	A0A059VAY4	Mycobacterium_phage	6.0e-14	35.2
WP_123091058.1|161539_162073_-	hypothetical protein	A5HL29	Phormidium_virus	4.6e-18	32.3
WP_123091057.1|162138_162825_-	hypothetical protein	A0A2H4J4Q3	uncultured_Caudovirales_phage	3.7e-36	48.0
WP_123091056.1|162824_164390_-|portal	phage portal protein	A0A142KAW3	Gordonia_phage	5.6e-141	56.0
WP_123091055.1|164399_165872_-	hypothetical protein	A0A0M3UKU0	Mycobacterium_phage	7.6e-47	31.7
WP_123091054.1|165945_166179_-	hypothetical protein	NA	NA	NA	NA
WP_123091053.1|166313_166589_-	HNH endonuclease	A0A160DHT4	Gordonia_phage	7.8e-06	44.1
WP_123091052.1|166672_167446_-	hypothetical protein	A0A1I9SC36	Mycobacterium_phage	1.4e-15	32.4

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP044548|186378:195984|DBSCAN-SWA
GATGAAGCGCTTCGCACCCCGGGCCGGCCGTACGAGCCGGGCCGCGACCAGCTCGGCCCTGGCAGTCTGCCTCGCCGCGGGTCTCGCGACGGCCTCGTGGGCCGCCGGTGACCCCGACCCCGCCGATAAGAAGCGCAAGGTCGACGACAGCATCAGTGCGACGAAGGCCGACCTCAGCGACACCTCCGCCGAGCTCGTCGAGGCCTACGACTCGCTCAAGAGCACCCGGGCCAAGCTGCCCGCCGCGCGCTCGAAGGCGAAGCAGGCCGAAGAGGTCGAGACCGCCGCGCAGACGAAGTACGACGACGCAGCCGCCGACCTGCGCGTGGCCAAGGCCGACGAGGCCAAGGCGCGCAAGGACATCCGCACGACGAGCACGAAGATCACCCGCGCCCGCTCCGACGTCGCGGGCTTCGCCGGCGAGGTCTACCAGCAGCAGGGTCTGGGCGACCTCTCCGTCGCGCTCGGGGCCGAGTCGCCCGGCGAGGTCATCGACCGCATGGTCATCGCCGACTCCGCCGGCGGCGCCCAGTCCGACTCGCTGGACTCGCTGACCACCTCGCGCGCCGACCTCGTCACCCAGCAGGACCGGCTCGAGGCGCTCAAGGACAAGACCCAGCAGGCCCGCGACGACGCGAGCACCGCGCTGTCGGACGCCAAGGTCGCCAAGACCGAGGCCGACGAGGCCGAGGCCGACCTCGAGTCGCTCGAGGCCGACCAGACGAGCCAGGCCAAGACGCTGCGCACCGAGCGGGCCAAGGAGCAGGGCCGGCTCACCGGTCTGCGCGCCGAGTCCGACCGCCTCGGCAAGATCCTCGAGGAGCGCGCCCGCAAGGCCCGGGTCAAGGCCGCGAAGATCAAGGCCGCCCGCGAGGCCGAGCAGGCCCGGCAGGCCGAGGCCCGTCGTCGGGCCGCCGCAGCCCCCGAGCCCGAGGCCGCCGACCCCAACCCGACGCCTCCCGCGACGAGCTCGGGGGTCCTCGCGGCCCCGGTCAACGCGCCGATCACCTCGGAGTTCGGGCTGCGCTTCCACCCGATCCTCAACTACTGGCGCCTGCACGCCGGTCGCGACTACGGCGGCGCGTGCGGCGCCCCGGTGCGCGCGGCGGCCGACGGCACGATCGTCTCGGCGGGCGTCGCCGGCGGGTACGGCAACCAGATCGCCGTCGACCACGGGGTCAAGCGCGGCGTGCTGCTCTCGACGACGTACAACCACCTGCAGGCCTTCGCCCGCACCTCCGGCACGGTCAAGCGCGGCGAGCTCATCGGCTACGTCGGCACGACCGGGACCTCGACCGGCTGCCACCTGCACTTCGAGACCTACGAGAACGGCACCCCGGTCGACCCGCGCCGCTGGCTCTGAGCCCCGGACAACCGAGTAGGTCCCGCCCGCGCCGCCAGGTAGCGTGATGCTCCCCGGCAGGGGCACGACGTACAGCGAGCGAGGACGGGTGAGATCGGTGGCCGACAAGGGCCAGGCGGGCCGCAAGGTCATCGCCAGCAACCGCAAGGCGCGGCACGACTACCTCATCGAGGACACCTACGAGGCCGGGCTGGCGCTCATGGGCACCGAGGTCAAGGCGCTGCGCATGGGCCGGGCCAACCTGGTGGACGGCTACGCGACCTTCTACCGCGACGAGCTCTACCTCGAGGGCGTGCACATCCCCGAGTACCTCAACGGCTCGTGGACCAACCACACCCCGCGGCGCCGTCGCAAGCTCCTCCTGCACCGCCGCGAGCTCGACAAGCTGCACGCCGCCGTCCACGCGAGCGGGCGGACCATCGTGCCGCTCTCGCTCTACTTCTCCGGCAGCGTCGTCAAGGTCGAGATCGCCGTCGCGACCGGCAAGAAGCACTACGACAAGCGCCACGCCCTGCGCGAGCGCCAGGACCGCCGTGAGACCGAGCGCGCGGTCTTCGGGCGGCACCGCGGGGAGTGACCCGCGCCCGGTCGCACCGGGTCGAGCACGACGAAGGGGTGGCCCGCCGAGTCGGCGGGCCACCCCTTCGCGCTGATCAGGGTCAGAGGGTCACTTGAAGGTGTCCTTGACGTTCTCGCCAGCGGCCTTGAGGTTGCCCTTGCTCTCCTGAGCCTGGCCCTCGGCCTGCATCTCCGGGTCGTCCTTGGCGTCGCCCGCAGCCTGCTTGGCCTTGCCGGCCAGCTGGTCCTTCGCGTTCTCGATCTTGTCGCCGATACCCATATGTGCCTCCTGGGGTGTGGTGGTCCGTGCTCCTCGACACTAGGCGGCCTGCCTGGGCATTTGGTGGCAGCGGGGGAGGGGAATGCGGTTGGCGGCCCCGCGGTTGAGGACGGTAGTCTCACCCCACAACTCAACAGCGTGACGTGGACACCCTCACGGGGGTGATCGGTTTCGACATTGGTCGGTCCTGCAGGAGAAGCGGGTCGAGGATGCACGGTCATCTCGTCAACGCCCCGTGCACATCAATAGGTGCCGATTCCAAGCGCACCGACTTCGCCCTCGCCGCCTGAGCGAGCCCGAAGTCCGTTGGTCTGAGCTCGATCTCGGCTCAGTAACCAGCGTCAGCTAGAGATCTTGCTGCGCAGCGGTGTCGGGACGCTGCGCGGGACTCCTTCTCGACTGGGCCTGTCAGGGGACGTGTGCGTGCGAGCCCTGAGGCCGAGAAAATCCATAGCGCACTGCACCCGGAGAAGTCCTGCTCGTCTACCAGTGGACGCGGGTTCGATTCCCGCCACCTCCACCACCGTGACCCACGTCAGCAGCCGATGGCCGCCCGCACGAGATCTATCGAGCGGGCGGCCGTCGGCATGCCCGGGGGAGGGCGAAGGGGGCGTGGCCCGGTGTGCTGGGATGAGGCCCGTGAGCACCTCGACGACGGGACGCCCCGTCCAGACCGGTCGGCGGCGTCTGGCCGTCGTCCTCACCGTGGTCGCCGTCCTCGTCCAGCTGGTCGTGCTCTACGACCCGAGCCCCGCCGGGGGAGGGGACATCCCCTTCGCCGACAAGGTGGTCCACGCCCTCGTCTTCGGCGTGCCCGTCGCCCTCGCCGGCTGGGCCCGGCTGCGGTGGGTGTGGGTGGCCGCGCTGATGGCCGTGCACGCCCCGGTGAGCGAGATCGTCCAGGGCCTGGCGCTGCCCGCCCGCAGCGGCGATCCCTTCGACGTCGTCGCCGACCTCGTCGGCGTGGTGCTCGGTGCGCTCGTCGCCCGCCGGCTGAGCGGTGTGTCAGGAGCACCGTCCGCGCGCTGGTAGACTCGGACCTTCGTCGTCACGGACTGCGCACTGCTGCGCCCCGCGATCGCTCCCGGTCGCTGATGATCCCTCACCCGTGACGACCGCCGGGCCGCACGGATGCCGCCCGGTCCATGGGCGCCGCAGAGCGCCTGAGACTCGTCTGGTGCGGTCACCCCTTCGCGGTGGCTCGAGACGTGTCTGCTCGAGCCAGAAGGTGATGTTGACATGCCCGCGAAGAACCCGAACAAGAAGGCCCGCTGGAGCGCTGCCGAGAAGGCTGCTGCCAGCACGAAGGGGCCGAAGAAGCCCTACCACCGCGGCCAGAAGCCGGCGGATGACGCCCCCCGCGGCGCCAAGCGTCCCGTGCGCGCCGCCGAGGACCGCCCGCGTCGCGTCCGCAAGGACGGCGCCGAGGACCAGGGCCAGCGTCGTTGGGAGCGCCGCGAGGACACCCGCCCCGGTGGCTTCCGCTCCGACGACCGTCGCGGTGGCGGCTTCCGCTCCGACGACCGTCGTAGCGACGACCGTCGTGGTGGCTTCCGCTCCGATGACCGTCGTGACGGCGGCTTCCGCAGCGACGACCGCCGCGGTGGTGGTTTCCGCAGCGATGACCGTCGTGACGGCGGCTTCCGCAGCGACGACCGCCGCGGTGGCGGCTTCCGCTCGGACGACCGTCGCAGCGATGACCGCCGTGGCGGCTTCCGCAGCGACGACCGTCGTACCGACGACCGCCGTGGTGGCTTCCGCAGCGACGACCGTCGTACAGATGACCGTCGCGGTGGCTTCCGCAGCGACGACCGTCGTAGTGACGACCGTCGTGGTGGCGGTTTCCGCTCGGACGACCGTCGTACTGATGACCGTCGTGGTGGCTTCCGCTCCGACGACCGTCGCACCGACGACCGCCGTGGCGGCTACCGCGGCGACGACCGCCGTGACGGTGGCTTCCGCTCCGACGACCGCCGGGGCGGGTCCCGCGAGGGCTTCCGTCGCGGTCCCCGCGACGAGCGCCAGGGCTACCGTCCCCGCTTCGACCGCGAGCAGACCTCGCAGGACCACCACCAGGACGCCGAGGCGGAGCGGATGGAGGCCGACAGCTGGGTCTCCGCGGCTCGCACGACGACCACCGAGCCCGTGACGGTCGCCGAGGACAACGGCTTCGCCGCGCTCGGCCTGCCCGAGCGCCTCGTCGAGCGGCTCGCCCGCGAGGGCATCTCGAGCCCCTTCCCGATCCAGGAGGCGACGATCCCCGACGCCCTGGCCGGCAAGGACGTCCTCGGCCGTGGCCAGACCGGGTCGGGCAAGACGCTCGCCTTCGGCCTGCCGACGATCGCCCGCCTCTCCGGCGAGCGCTCGAAGCCCCGCCGCCCCCGTGCCCTCGTCCTCGTGCCGACGCGTGAGCTCGCGATGCAGGTGAGCGACTCGCTCGAGCCGCTCGTGCACGTCGCCGGGCTGCGTCACAAGCTCGTCGCCGGTGGCCTGTCCTACACGGGTCAGATCGCCGCGCTCGACAAGGGCGTCGACCTGCTCATCGCGACCCCGGGCCGTCTCGTCGACCTGCTCGACCGCGAGGCCGTCATCCTCGACTCCATCGAGGTGACGATCCTCGACGAGGCCGACCACATGGCCGACATGGGCTTCGTCCCGGCCGTGACCCGCGTCCTCGACGAGGTCCCCGAGGGCGGGCAGCGCCTGCTCTTCTCGGCGACGCTCGACAAGGGTGTCGACACCCTGGTCCAGCGCTACCTCGTCGACCCGGTGACCCACTCGACGAACGACGCCACCGCGTCGGTCGACACGATGGAGCACCACATCCTCGTCATCGACCCGCAGCACAAGAAGGTCATCACCGCGGAGGTGGCCAACCGCGAGGGCCGCACCGTCGTCTTCTGCCGCACCAAGCTCGGTGCCGACCGCGTCGCCCTCCAGCTGCGCGAGTCCGGTGTCCGCGCCGCGGCCCTCCACGGCGGTCTGACCCAGGGCGCCCGCAACAAGGTGCTCGGGGCCTTCCGCACCGGTCGGATCCCCGTGCTCGTCGCCACCGACGTCGCTGCCCGCGGCATCCACGTCGACGACGTCTCGGTCGTCCTGCAGGCGGACCCGCCCGCGGACCACAAGGACTACCTCCACCGCGCGGGCCGCACCGCCCGCGCCGGTGAGCGCGGCACCGTCGTCACCCTCGCCCTGCCGCACCAGCGCAAGATGATGGAGCGCATGGCGACCGACGCCGGTCTCGAGGCCCGTCCGGTCAAGGCGGCCCCCGGTGACGAGGTCCTCGAGGCCGCCGGTGCGGCGCCCGTGAGCGGCGTGCCGATCGACGAGGCCGACTTCCGCAAGCTGCTCGACCCCCGGCCTGCACGGCGCCACGGTGGCACCGGCGGCCCGCGCGGTGCGCGCACCGGTGGGCAGTACCGGGGCGGCGGCCAGCGCCGCGGGCCGCGTCACGGGTGATGATGTAGGCATGGACAGCCTGGCCGGACGTCTGCTCGTGAGCACCCCTGAGATCACCGACGGGGTCTTCGACCGCAGCATCGTGCTCGTGCTGGCCCATGACGAGCAGTCCGCCGAGGGCGTCGTCATCAACAAGCCCGTCCAGGCGCCGATCGACGCCGTCCTGCCAGGGTGGCAGGACGGCGCGAGCGAGCCGCAGAAGGTCTTCCAGGGCGGGCCCGTCCAGACCGACTCGGCGGTCGGGCTCGTCGGGGTCCCCGGCGACGGGGAGCCCCCCGTGGGGGTCAAGCGCCTCTTCGGCGGGATCGGCCTGGTCGACCTCGACGCCCCGCAGGAGAGCGTGTGGCCCGCGATCAGCGCGCTGCGCATCTTCGCCGGGTACTCGGGGTGGACCGCCCCGCAGCTCGCCGGCGAGATCGAGCGGGGCGGCTGGTTCGTCTGCGACGCCGAGATCGGCGACGTCTTCGACGCGGACCCGGCGACGCTGTGGCGTCGGGTCCTGCGTCGTCAGCGCGGCGTCATGGCCTGGGTCTCGACCTACCCCGAGGACCCGACCCAGAACTGACGCGGCGCCGACGCGGGGCTGACCCCCTTCGCGCCTCGTCCTAGACTCGCCCCATGAGCGAGCCACTGCCCCCGAGCGGGCCCGACGCCGACCCCACCTCTCCGGGGACCTCCACCGGGTTGCTCGAGCGCACTGAGGTCACCCCGCAGCTGCAGGAGCCGGGCGACCACGAGCGCTTCTCGCACTACGTGCGCAAGGAGAAGATCCTCGAGTCGGCGCTGTCCGGCGAGCCCGTGACGGCCCTGTGCGGCAAGAAGTGGATCCCCGGTCGCAACCCCGACAAGTTCCCGGTGTGCCCGATCTGCAAGGAGATCTACCAGGGCCTGCGCGACCCCCAGGACGGCGAGGACTGACCCCTCTCGCACCCGGGAGCGCTTGGCCGAACCTTTGCCAACTCCTGGGTGCAGACGGGGTGCCGCCCTGACCATCGGGCTCCTAGCGTCCGAGGTAACGGCCGGGACACACCCGGCCCGTCACCCCTGATGGAGAGCCTGTGAAGTCCACGCGCGCCCTTGTCGCCCCCGCCCTGCTCGCCCTGGCCCTGACCGGGTCCGCCCCCGCTCTGCCCGCCCTCGCCGGCGCGGACGCCGCCGACGCCGGCACCTCCCGCGTCTCGGCCTCGCACGCCGACGAGCACTGCGACGAGGAGGTCTCCGCGACCGCCCGCAGCACCGGCAAGGGCGGCAAGGTCAAGGACCCGCACACCCTGAGCCAGGCCCAGGTCGACATCCGCGAGGACGCCTTCCAGGACGCGCTCGTCGACAAGGGCCTGCGGCTCAGCCCGACCGGCAAGGTCGCCGCGAAGGGCAAGCCCGGCACCGCGCAGTTCGCCTCGACGAACGTCCCCGTGTACTTCCACGTCATCACCGACGGGACGAACGGCAAGCTCACCTCGACCCAGATCAGCTCGCAGGTCAAGGTCCTCAACGACGCCTACGCGGGCTCGGGCTTCTCCTTCACCCTCGCCGGCACCGACACCACGGTGAACTCCGCCTGGTACAACGGCCTCGACCACGGCTCGACCGCCGAGTCGCAGATGAAGAGCGCCCTGCGCAAGGGCGGCAAGAACGCCCTCAACGTCTACAGCGCCGACCTCGCCGGCGGTCTGCTCGGCTGGGCGACCTTCCCCACCCGCAACATCGGCAGCAACGACGGCGTCGTCATCCTCGACGGCTCGGTGCCCGGCGGCAACGCCGCGCCGTACAACCTCGGCGACACCGGCACCCACGAGGTCGGCCACTGGCTCGGGCTGTACCACACCTTCCAGGGCGGCTGCCAGGACGGCGACTACGTCGCCGACACCCCCGCCGAGGCCCAGCCCGCCTCCGGCTGCCCGACCGGCGCCGACACCTGCCCGGCCAAGCCCGGTCTCGACCCGATCCGCAACTTCATGGACTACTCCGACGACGCGTGCATGGACCACTTCACCGCCAACCAGGTGACCCGCATGCAGAACCAGTGGGTGACCTACCGGGCGAGCTGACCCGACCCCGACGAAGGGGGCGTCGCACGAGGTCGTGCGGCGCCCCCTTCGTCATGCCGTCCCGCCGTGCCGTCGGCAGTCTCGCCGGGCACGCTTTCGTCGCAGTCGGTGCGGCGGCTTACCCTGGTCGGCGTCATGAGCCAGCACGCCGCGTCGAACCTGCCCCCCGCCTTCCCGGAGCGGGCAGCCTGGGGGACCGCCGGGGCGCTGCGGGCCTGGCAGGCCGAGGCGCTGGAGAAGTACCTCGGCAGCGGCGCGCGCGACTTCCTCGCCGTCGCGACCCCGGGAGCGGGCAAGACGACCTTCGCCCTGCGGGTCGCCGCCGAGCTGCTGACCCGCGGCGAGATCGAGGCGGTGACGGTCGTCGCGCCCACCGAGCACCTCAAGACGCAGTGGGCCGACGCCGCGGCCCGCGTGGGCATCCACCTCGACCCGAAGTTCTCGAACTCCGTCGGCTCGACGAGCAGCGACTACGACGGCGTCGCCGTCACCTACGCCCAGGTCGCCTCGCGCGCCTCGGTCCACGAGGCCCGCACGAGGTCGCGGCGCACCTTCGTCATCCTCGACGAGATCCACCACGGCGGCGACAACAAGTCGTGGGGCAGCGCGATCCGCGAGGCCTTCGAGCCGGCCACCCGCCGTCTCGCGCTCACCGGCACGCCCTTCCGCTCCGACACCAACCCCATCCCCTTCGTCACCTACGAGTACGGCGACGACGGGATCCTGCGCTCCTCGGCCGACTACACCTACGGCTACGCCCAGGCGCTCGCCGACCACGTCGTGCGCCCCGTGCTCTTCATGGCCTACGGCGGCGGCATGCGCTGGCGCACCCGCGCGGGCGACGAGGTCGCGGCCCGTCTCGGCGAGCCGATGACCAAGGACCTCGCGGCGCAGGCCTGGCGCACCGCGCTCGACCCGAAGGGGGAGTGGGTCCCCTCGGTCCTCTCGGCCGCCGACAAGCGGCTGACCGAGGTGCGTCGGCACGTCGAGGACGCCGGGGGGCTCGTCATCGCGAGCAACCAGACCCAGGCCCGCGCCTACGCGCGCATCCTCGAGTCGATCACCGGCGAGAAGCCCACCGTCGTGCTCTCCGACGACCCGGGCAGCTCGGCGCGCATCGAGACCTTCGCCGCGAGCAGCTCGCGGTGGATGGTCGCCGTGCGCATGGTGTCCGAAGGGGTGGACGTCCCGCGCCTGTGCGTCGGGGTCTACGCGACGTCGACCTCGACGCCGCTGTACTTCGCCCAGGCCGTCGGGCGCTTCGTGCGGGCGCGCAAGCGCGGCGAGACCGCCTCGGTCTTCCTGCCGAGCGTGCCGGTGATCCTCGCCCACGCCGGGACGATGGAGGTCGAGCGCGACCACGCCCTCGACCGCCCCGAGCCCGAGGCCGGCGAGGAGCAGATCTGGTCCGAGGAGGAGGGCCTGCTCGAGGAGGCCAACCGCGACGAGGGCGCGAGCGACGACCTGCTCGGCAGCTTCGAGGCGCTCGAGTCCGACGCGCACTTCGACCACGTGCTCTACGACAGCAAGCAGTGGGGCCTGCACGCCGACGTCGGCTCCGACGACGAGCAGGACTACCTCGGCCTGCCCGGTCTGCTCGAGCCCGACCAGGTGCACGCGCTGCTCTCCGAGCGGCAGAGCAAGCAGTCAGCGAAGACCGGTCGGAAGCGCCCGGCCGAGCCGCAGACGGTCTCGGCGCACCGGGCGCTGGCCAGCCAGCGCAAGGAGCTCAACTCGCTCGTCTCGGCCTACGCGACCAAGAAGTCCGTCGCCCACGCGAACGTCCACATGGACCTGCGCCGGGCGTGCGGCGGGCCGGAGCTGGCCACGGCGACGAGCGAGCAGGTCACCGAGCGGATCGAGACCATCCGGCGCTGGTTCGTCGGCCGTCGGTGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP044548|186378:195984|194223_195984_+|WP_068273622.1|DBSCAN-SWA
MSQHAASNLPPAFPERAAWGTAGALRAWQAEALEKYLGSGARDFLAVATPGAGKTTFALRVAAELLTRGEIEAVTVVAPTEHLKTQWADAAARVGIHLDPKFSNSVGSTSSDYDGVAVTYAQVASRASVHEARTRSRRTFVILDEIHHGGDNKSWGSAIREAFEPATRRLALTGTPFRSDTNPIPFVTYEYGDDGILRSSADYTYGYAQALADHVVRPVLFMAYGGGMRWRTRAGDEVAARLGEPMTKDLAAQAWRTALDPKGEWVPSVLSAADKRLTEVRRHVEDAGGLVIASNQTQARAYARILESITGEKPTVVLSDDPGSSARIETFAASSSRWMVAVRMVSEGVDVPRLCVGVYATSTSTPLYFAQAVGRFVRARKRGETASVFLPSVPVILAHAGTMEVERDHALDRPEPEAGEEQIWSEEEGLLEEANRDEGASDDLLGSFEALESDAHFDHVLYDSKQWGLHADVGSDDEQDYLGLPGLLEPDQVHALLSERQSKQSAKTGRKRPAEPQTVSAHRALASQRKELNSLVSAYATKKSVAHANVHMDLRRACGGPELATATSEQVTERIETIRRWFVGRR
>NZ_CP044548|186378:195984|192050_192605_+|WP_123091028.1|DBSCAN-SWA
MDSLAGRLLVSTPEITDGVFDRSIVLVLAHDEQSAEGVVINKPVQAPIDAVLPGWQDGASEPQKVFQGGPVQTDSAVGLVGVPGDGEPPVGVKRLFGGIGLVDLDAPQESVWPAISALRIFAGYSGWTAPQLAGEIERGGWFVCDAEIGDVFDADPATLWRRVLRRQRGVMAWVSTYPEDPTQN
>NZ_CP044548|186378:195984|186378_187740_+|WP_123091031.1|DBSCAN-SWA
MKRFAPRAGRTSRAATSSALAVCLAAGLATASWAAGDPDPADKKRKVDDSISATKADLSDTSAELVEAYDSLKSTRAKLPAARSKAKQAEEVETAAQTKYDDAAADLRVAKADEAKARKDIRTTSTKITRARSDVAGFAGEVYQQQGLGDLSVALGAESPGEVIDRMVIADSAGGAQSDSLDSLTTSRADLVTQQDRLEALKDKTQQARDDASTALSDAKVAKTEADEAEADLESLEADQTSQAKTLRTERAKEQGRLTGLRAESDRLGKILEERARKARVKAAKIKAAREAEQARQAEARRRAAAAPEPEAADPNPTPPATSSGVLAAPVNAPITSEFGLRFHPILNYWRLHAGRDYGGACGAPVRAAADGTIVSAGVAGGYGNQIAVDHGVKRGVLLSTTYNHLQAFARTSGTVKRGELIGYVGTTGTSTGCHLHFETYENGTPVDPRRWL
>NZ_CP044548|186378:195984|188407_188578_-|WP_068273614.1|DBSCAN-SWA
MGIGDKIENAKDQLAGKAKQAAGDAKDDPEMQAEGQAQESKGNLKAAGENVKDTFK
>NZ_CP044548|186378:195984|189817_192040_+|WP_123091029.1|DBSCAN-SWA
MPAKNPNKKARWSAAEKAAASTKGPKKPYHRGQKPADDAPRGAKRPVRAAEDRPRRVRKDGAEDQGQRRWERREDTRPGGFRSDDRRGGGFRSDDRRSDDRRGGFRSDDRRDGGFRSDDRRGGGFRSDDRRDGGFRSDDRRGGGFRSDDRRSDDRRGGFRSDDRRTDDRRGGFRSDDRRTDDRRGGFRSDDRRSDDRRGGGFRSDDRRTDDRRGGFRSDDRRTDDRRGGYRGDDRRDGGFRSDDRRGGSREGFRRGPRDERQGYRPRFDREQTSQDHHQDAEAERMEADSWVSAARTTTTEPVTVAEDNGFAALGLPERLVERLAREGISSPFPIQEATIPDALAGKDVLGRGQTGSGKTLAFGLPTIARLSGERSKPRRPRALVLVPTRELAMQVSDSLEPLVHVAGLRHKLVAGGLSYTGQIAALDKGVDLLIATPGRLVDLLDREAVILDSIEVTILDEADHMADMGFVPAVTRVLDEVPEGGQRLLFSATLDKGVDTLVQRYLVDPVTHSTNDATASVDTMEHHILVIDPQHKKVITAEVANREGRTVVFCRTKLGADRVALQLRESGVRAAALHGGLTQGARNKVLGAFRTGRIPVLVATDVAARGIHVDDVSVVLQADPPADHKDYLHRAGRTARAGERGTVVTLALPHQRKMMERMATDAGLEARPVKAAPGDEVLEAAGAAPVSGVPIDEADFRKLLDPRPARRHGGTGGPRGARTGGQYRGGGQRRGPRHG
>NZ_CP044548|186378:195984|187786_188317_+|WP_123091030.1|DBSCAN-SWA
MLPGRGTTYSERGRVRSVADKGQAGRKVIASNRKARHDYLIEDTYEAGLALMGTEVKALRMGRANLVDGYATFYRDELYLEGVHIPEYLNGSWTNHTPRRRRKLLLHRRELDKLHAAVHASGRTIVPLSLYFSGSVVKVEIAVATGKKHYDKRHALRERQDRRETERAVFGRHRGE
>NZ_CP044548|186378:195984|189265_189610_+|WP_123091530.1|DBSCAN-SWA
MAVVLTVVAVLVQLVVLYDPSPAGGGDIPFADKVVHALVFGVPVALAGWARLRWVWVAALMAVHAPVSEIVQGLALPARSGDPFDVVADLVGVVLGALVARRLSGVSGAPSARW
>NZ_CP044548|186378:195984|192658_192958_+|WP_068273618.1|DBSCAN-SWA
MSEPLPPSGPDADPTSPGTSTGLLERTEVTPQLQEPGDHERFSHYVRKEKILESALSGEPVTALCGKKWIPGRNPDKFPVCPICKEIYQGLRDPQDGED
>NZ_CP044548|186378:195984|193167_194088_+|WP_123091529.1|protease|DBSCAN-SWA
MPALAGADAADAGTSRVSASHADEHCDEEVSATARSTGKGGKVKDPHTLSQAQVDIREDAFQDALVDKGLRLSPTGKVAAKGKPGTAQFASTNVPVYFHVITDGTNGKLTSTQISSQVKVLNDAYAGSGFSFTLAGTDTTVNSAWYNGLDHGSTAESQMKSALRKGGKNALNVYSADLAGGLLGWATFPTRNIGSNDGVVILDGSVPGGNAAPYNLGDTGTHEVGHWLGLYHTFQGGCQDGDYVADTPAEAQPASGCPTGADTCPAKPGLDPIRNFMDYSDDACMDHFTANQVTRMQNQWVTYRAS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_123091031.1|186378_187740_+	M23 family metallopeptidase	G9BW84	Planktothrix_phage	1.1e-15	40.7
WP_123091030.1|187786_188317_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	7.2e-32	51.0
WP_068273614.1|188407_188578_-	CsbD family protein	NA	NA	NA	NA
WP_123091530.1|189265_189610_+	VanZ family protein	NA	NA	NA	NA
WP_123091029.1|189817_192040_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.3e-36	27.3
WP_123091028.1|192050_192605_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_068273618.1|192658_192958_+	DUF3039 domain-containing protein	A0A160DF89	Gordonia_phage	2.2e-06	39.7
WP_123091529.1|193167_194088_+|protease	zinc metalloprotease	A0A2K9L5D3	Tupanvirus	4.2e-19	41.1
WP_068273622.1|194223_195984_+	DEAD/DEAH box helicase	I4AZM6	Saccharomonospora_phage	1.5e-86	37.4