CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040249	Mycobacterium avium subsp. hominissuis strain 101174 plasmid pMARIA, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP040248	Mycobacterium avium subsp. hominissuis strain 101174 plasmid pFLAC0181_CHOP101, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP040250	Mycobacterium avium subsp. hominissuis strain 101174 chromosome, complete genome	5 crisprs	cas3,csa3,RT,WYL,cas4,DEDDh,DinG	0	3	2	0

1. NZ_CP040250

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040250_1

• CRISPR_ID: NZ_CP040250_1
• CRISPR_location: 626064-626195
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP040250_1

Consensus_repeat	Method
CGCTCGCCGAGGGGCAGGCGCTCGC	CRISPRCasFinder

spacers of NZ_CP040250_1

>1.1|626089|32|NZ_CP040250|CRISPRCasFinder
GACGCCAGAGCCCGACGGTCACGCTGGCGTGA
>1.2|626146|25|NZ_CP040250|CRISPRCasFinder
TGAGAGAGGCGCTCGCCGAGAGAGG

CRISPR arrays and Neighbor proteins around NZ_CP040250_1

CRISPR arrays

The CRISPR arrays of NZ_CP040250_1

>merge|NZ_CP040250|1|626064-626195|CRISPRCasFinder
CGCGCGCCGAGCGTCACGCTGGCGTGACGCCAGAGCCCGACGGTCACGCTGGCGTGACGCTCGCCGAGGGGCAGGCGCTCGCTGAGAGAGGCGCTCGCCGAGAGAGGCGCTCGCCGAGGGGTAGGCGCTCGC

>NZ_CP040250|1|1|626064-626195|CRISPRCasFinder
CGCGCGCCGAGCGTCACGCTGGCGT	GACGCCAGAGCCCGACGGTCACGCTGGCGTGA
CGCTCGCCGAGGGGCAGGCGCTCGC	TGAGAGAGGCGCTCGCCGAGAGAGG
CGCTCGCCGAGGGGTAGGCGCTCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040250.1|WP_003874076.1|637998_638295_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_023895717.1|621138_622785_-|acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|236239
NZ_CP040250.1|WP_009979657.1|635403_636885_+|aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143457
NZ_CP040250.1|WP_033710780.1|615942_617097_+|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl|CDD|181041
NZ_CP040250.1|WP_009979647.1|625282_625966_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP040250.1|WP_033710775.1|618707_619922_-|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
NZ_CP040250.1|WP_023895718.1|626202_627912_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173838
NZ_CP040250.1|WP_003874069.1|630396_631653_+|DUF3068-domain-containing-protein	unknown	unknown	gnl|CDD|371444
NZ_CP040250.1|WP_033711072.1|633342_634509_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP040250.1|WP_031353758.1|618298_618667_-|ring-cleavage-extradiol-dioxygenase	unknown	unknown	gnl|CDD|319925
NZ_CP040250.1|WP_033710774.1|617112_618090_-|aromatic-acid-exporter-family-protein	unknown	unknown	gnl|CDD|226614
NZ_CP040250.1|WP_033711070.1|631661_633359_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_003879120.1|637409_637997_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP040250.1|WP_023895716.1|620169_621099_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP040250.1|WP_033710773.1|615091_615391_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_009979649.1|628037_629018_+|phosphotriesterase	unknown	unknown	gnl|CDD|366928
NZ_CP040250.1|WP_019733639.1|634590_635358_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP040250.1|WP_088294882.1|629048_630275_-|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_CP040250.1|WP_009979644.1|622865_624284_+|NADP-dependent-succinic-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|181826
NZ_CP040250.1|WP_009979645.1|624350_625286_-|R2-like-ligand-binding-oxidase	unknown	unknown	gnl|CDD|236242

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040250.1|WP_023895717.1|621138_622785_-|acetolactate-synthase-large-subunit	gnl|CDD|236239	PRK08322, PRK08322, acetolactate synthase large subunit.	0
NZ_CP040250.1|WP_009979657.1|635403_636885_+|aldehyde-dehydrogenase	gnl|CDD|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
NZ_CP040250.1|WP_033710780.1|615942_617097_+|NAD-dependent-formate-dehydrogenase	gnl|CDD|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NZ_CP040250.1|WP_009979647.1|625282_625966_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.86081e-11
NZ_CP040250.1|WP_033710775.1|618707_619922_-|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	4.14348e-17
NZ_CP040250.1|WP_023895718.1|626202_627912_-|acyl-CoA-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	1.41675e-27
NZ_CP040250.1|WP_003874069.1|630396_631653_+|DUF3068-domain-containing-protein	gnl|CDD|371444	pfam11271, DUF3068, Protein of unknown function (DUF3068). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	1.54086e-103
NZ_CP040250.1|WP_031353758.1|618298_618667_-|ring-cleavage-extradiol-dioxygenase	gnl|CDD|319925	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	7.73549e-27
NZ_CP040250.1|WP_033710774.1|617112_618090_-|aromatic-acid-exporter-family-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.57888e-26
NZ_CP040250.1|WP_003879120.1|637409_637997_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.17419e-10
NZ_CP040250.1|WP_023895716.1|620169_621099_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.62003e-38
NZ_CP040250.1|WP_033711072.1|633342_634509_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	6.92444e-52
NZ_CP040250.1|WP_009979649.1|628037_629018_+|phosphotriesterase	gnl|CDD|366928	pfam02126, PTE, Phosphotriesterase family.	3.54084e-157
NZ_CP040250.1|WP_019733639.1|634590_635358_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.28725e-21
NZ_CP040250.1|WP_088294882.1|629048_630275_-|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	7.479e-46
NZ_CP040250.1|WP_009979644.1|622865_624284_+|NADP-dependent-succinic-semialdehyde-dehydrogenase	gnl|CDD|181826	PRK09406, gabD1, succinic semialdehyde dehydrogenase; Reviewed.	0
NZ_CP040250.1|WP_009979645.1|624350_625286_-|R2-like-ligand-binding-oxidase	gnl|CDD|236242	PRK08326, PRK08326, R2-like ligand-binding oxidase.	0

Protein sequences

>NZ_CP040250.1|WP_009979647.1|625282_625966_-|TetR/AcrR-family-transcriptional-regulator
MPTVTWARVDPARRAAIIEAAESEFGAHGFSRGSLNVIARKAGVAKGSLFQYFADKRDLYAFIADIGSQRVRGYIEQLIRELDPTRPFFEFLTDLLDGWVAYFADHPHERALHAAATLEVDTEARISVQNVIHRHYLEVLRPLVRDARLRGDLRADSDTDALLSLLLLIFPHLALAPYMRGLDPVLGLDEPTPEQPALAVRRLVAVLAAAFSPAPAHFATPRSEEVT
>NZ_CP040250.1|WP_009979645.1|624350_625286_-|R2-like-ligand-binding-oxidase
MNRTRSASMVQGGLNWDSLPLKLFAGGNAKFWNPADIDFSRDRADWERLTDDERSYATRLCAEFIAGEESVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHVQVFRMWLDAVGVTDDLHHFLDDVPSYRTIFYEELPDCLNALTIDPSPAAQVRASVTYNHMVEGMLALTGYFGWHKICVERGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWGVFETRMNELMPLGLRLIEEGFALYDPMPFDLSVDEFMAYASDKGMRRFGTIASARGRPLAEIDLDYTPVQLEDTFADEDARALAAV
>NZ_CP040250.1|WP_009979644.1|622865_624284_+|NADP-dependent-succinic-semialdehyde-dehydrogenase
MPIATINPATGETVKTFTPASDAEVDAAIARAYERFLDYRHSTTFAQRAQWANATADLLEAEADEVAAMMTLEMGKTLKSAKAEALKCAKGFRYYAQNAEQLLADEPADAGKVGAARAYIRYQPLGVVLAVMPWNFPLWQAVRFAAPALMAGNVGILKHASNVPQSALYLADVITRGGFPEGCFQTLLVPSSAVERILRDPRVAAATLTGSEPAGQSVAAIAGDEIKPTVLELGGSDPFIVMPSADLDEAVKTAVTARVQNNGQSCIAAKRFIVHTDIYDTFVDKFVEQMKALKVGDPTDPATDVGPLATESGRDEIAKQVDDAVAAGATLRCGGKPLDGPGWFYPPTVVTDITKDMALYTEEVFGPVASMYRAADIDEAIEIANATTFGLGSNAWTNDAAEQQRFIDDIEAGQVFINGMTVSYPELGFGGVKRSGYGRELAGLGIRAFCNAKTVWIGSSKSGDAGGGSKVE
>NZ_CP040250.1|WP_023895717.1|621138_622785_-|acetolactate-synthase-large-subunit
MSKAAELIVKCLENEGVSVVFGLPGEENIRFVQALAASPIRYVLTRHEQAASFMAEMYGRVTGRAAVVSATLGPGAINMQLGVADATTNSTPLVAISAQVGHDREFKESHQYVDLVSMFAPITRWAAGIPTARAIPEMVRKAFKLAESERPAAVYLAVPEHIDADETDYELGPLPRNVVRPDAPSPRQVERAAQILRNAKRPVVLAGHGAARADATKALVRFSEEFGIQVANTFHGKGVMPDDHPNSIGTLGFMRHDYVNFGFDHADAVIAVGYELQEFDPVRINPQADKKIIHMHRFPAEVDAHYSVDVGIIGDISDSLNALTDALSGHRFEHAADVPGSGLLTDEFARGQQDSRYPLAPARVVADTRAALGRSDVVLVDTGATKMWMARLYPTYERNTCLISNGLSTMSFALPGALGVKLAQPESKVLAVVGDGAFLMNSQEIETAVRERIPLVVLIWEDGGYGLIEWKMDLELGAHYYVKFANPDVVTYAESFGAKGYRISHADELLPTLRAALDDDGVSLISCPVDYSENLRLTNRLGELDETL
>NZ_CP040250.1|WP_023895716.1|620169_621099_-|LysR-family-transcriptional-regulator
MLFRQLEYFVALASERHFARAARACYVSQPALSEAIRKLEQELNVPLVRRGQKFEGLTPEGERLVLWARRILADHDALKQEVAALQTGLTGELRLGVIPAASSIVALLTDPFCAAHPLVRVQLETSLRSAEIVQRLRRFELDAGVLYPDRQDVADLLVTPLYTEQQVLIAGAELLLDPSETISWSDALTLPMCLLNQGMRGRRLIDDALATLELTVTPQLETDSVATLLAHVGTGRWASIIPQTWIHSLRPPAGARILRLENPTVTATVALVTSATEPGSVLTRALVQTARGAGINDVLRKAAPGYSAG
>NZ_CP040250.1|WP_033710775.1|618707_619922_-|PucR-family-transcriptional-regulator
MKDLRAPVNGVDGDSASALVAVPKSQGAQTIRPDSVSRLVGALLDDHAAVVGRVRSVIRSRLPVYRSVADEALEAELEWVLRSAVGGREALHEPQIAGLAAIGEARARDGVPVDDMLRAWRIGVEVVVECAREAARRLGVDDARVLELVQSALAWSDIAMATSAKAHRRTERALALEAEESDAEFVRGALMGSLPAAELRMHAELRGLDPGAEYVAVRARLGGDGPHLRLEQSLGFQDPAHSRRGLCALLDGDLAGFLIEPPRDVEGVVGFGPPRPLTRLSESYRMAARALVTAEACGLRGAYDIAALGLRTAVAIDADVGELLRKRYLEPLSVGGSSRELIATVRTYLACGMHVERTATRLFVHQNTVRYRLARFEELTGASLRDTEVVTEVWWVLELAAMRL
>NZ_CP040250.1|WP_031353758.1|618298_618667_-|ring-cleavage-extradiol-dioxygenase
MRRVDYVIQYVESLERSVTFYRDVIGLEVRIEGDGYVEFEMPNTKFSLFERSKLFELIGREGGTAPCGEIGFLVDDVDEEATRLRGLGVEILSGPVDRPWRERTLHIADPDGNVIEFAQKLR
>NZ_CP040250.1|WP_033710774.1|617112_618090_-|aromatic-acid-exporter-family-protein
MWPIAQTTVAAGLAWYLAHDVLDHREPFFAPIAAAVCLWMTNRVRAELAVEMIIGVALGIGAGTVVLAVFGAGPIGMGAAVMLSLTLAVLIARSFSTQRSMFVNQSVISAILIMAFPHTGLGVERLYDALIGGGLAVVFSILLFPKNPLAVLHDASGELLTALHDILAQICCRSTDSASPDQGWALSAADRLQRCSASLIEARGTAGQLARVCPRRWPLRGAVGAADRQAVHVALFGSSVLQLARTLTSVRIPGGPHAEAFRAAVDDLRDAVSALAAGHPETAAAHAESARRHSAALPAGSPASVAVVIDACIDELQQAIGPRRS
>NZ_CP040250.1|WP_033710780.1|615942_617097_+|NAD-dependent-formate-dehydrogenase
MAKCVMVLYPDPVDGYPPKYARDSIPVIHSYPDGSSLPTPSKIDFTPGELLGCVSGALGLRKFFEDGGHELVVTSDKDGPDSEFERELPDADIVISQPFWPAYITKERFAKARNLKLALTAGIGSDHVDLAEAQARGVTVAEETWSNSISVAEHTVMQILALVRNFVPSHQWIRDGGWNIADCVQRSYDVEGMDVGVIAAGRIGRAVLERMKPFGVNLHYFDVHRLSPEYEKQLGVTYHPDVESLARSVDVVSIHSPLIAQTHHMFNEKLLKSMRRGSYIVNTARAEETDHKAIVAALESGQLAGYAGDVWFPQPPPPDHPWRTMPNHAMTPHISGSSLSAQARYCAGTREILEDWFAGRPIRSEYLIVEGGKFAGTGAKSYAQ
>NZ_CP040250.1|WP_033710773.1|615091_615391_-|hypothetical-protein
MQDETLAVIRSLVSDGLVRLGAQVMVGEHLGGVATEGERFVAWDQPLERSMHKISHVYLKHYDDPEQWMYAAWMQLTDKGEQLARSFEQADLDSYRKFQ
>NZ_CP040250.1|WP_023895718.1|626202_627912_-|acyl-CoA-dehydrogenase
MLLNPNHLQRRYPDRRSAEIMAATVDFFESRGKARLKSDDHERVWYSDFLEHIGRERIFASLLTPTRYGAPDCRWDTYRISGFAEILGFYGLNYWYPFQVTALGLGPIWMSDNDQAKRKAAGLLEAGEVFAFGLSEQTHGADVYQTDMNLTPAPGGGWTAAGQKYYIGNANVARMVSTFGKFAGGTTDSEYVFFAADSRHERYRLIKNVVNSQNYVGNFALSDYPVTEADILHRGPEAFHAALNTVNVCKYNLGWGAVGMCTHAMYEAVTHASNRILYGTVVTDFSHVRRLLIDAYARLVAMRLVATRACDYMRSASATDRRYLLYSPLTKAKITGEGERVITALWDVIAAKGVEKDTIFEAMTREIGLLPRLEGTVHINIGLLGKFMPNYLFAPSGELPVIGRRDDAADDEFLFAQGPTGGLGKVRFGDWRAPFNGFAHLPNVALLRAQIDVLAEMLASATPDALQQKDIDFAFAVGQLFATVPYAQLILEEATLSGVDDALIDEIFGVLVRDFNTYAVELSDKPATTEQQARFAMRMIRRPVHDPARYDQIWKEQVLPLSGAYQMRP
>NZ_CP040250.1|WP_009979649.1|628037_629018_+|phosphotriesterase
MSELNTARGPIDTAALGVTLMHEHVFIMTTEIAQNYPEAWGDEEQRVADAIDRLNELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLYTYNDVPFYFHYLGPGAELGGPEIMTDMFVRDIEQGIADTGIKAGILKCATDAPGVTPGVERVLRAVAQAHKRTGVPISTHTHAGLRRGLDQQRIFEEEGVDLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPFEDRVNIVAQMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALKQRGVTDEQLHTMLVDNPRRIFERQGPYG
>NZ_CP040250.1|WP_088294882.1|629048_630275_-|acyltransferase
MPGCTRSPGRAHRQTVVVSDDQRVGGVRSFLPAVEGMRACAAMGVVVTHVAFQTGHSSGVDGRLFGRFDLAVAVFFALSGFLLWRGHAAAARDLAPRPRTGHYLRSRVVRIMPAYLVAVVVILTLLPDADHPSPTVWLANLTLTQIYVPLTLTGGLTQMWSLSVEVGFYLALPVLALLARRLPVTARVPAIATLGALSWAWGWVPVHPGSGLNPLNWPPAFFSWFAAGMLLAEWVHGGIGRPVRLAQSRTGRVLLAVVAVAAYLVAASPLAGPEGLVPGTPAQFAVKTAMGSLVAFALIAPLVLDRMDTPHRVLGTTVMVTLGRWSYGLFIWHLAALAMVFPVLGTFPFTGRMPAVLVLTLIFGFAIAAVSYALVESPCREALRRWGKRHQPAAPRQLIDAEADAIAP
>NZ_CP040250.1|WP_003874069.1|630396_631653_+|DUF3068-domain-containing-protein
MNRAVMLRFAACGIIGLGAALLIAALLLTTYTTSRITKVPLDVDATLISDGTGTALDSASLSTDHVVVNQNVPLVSQQQISVESPANADVVTLQVGSSLRRTDKQKDTGLLLAIVDTVTLNRKTATAVSDDTHTGGAVQKPRTINDENPPTAIPLRHDGLSYRFPFHTEKKTYPYFDPIAQKPFDVNYDSQEDVNGLTTYKFTQNVGYNADGKLVAPVAYPSLYADQATDSKFTAPASMWGIQGGDPNEQITMTRFYAAQRTFWVDPVSGTIVKQTEHAHHYFARDPLKPELTLADYKVTSNEDTVESQVNAARDERDRLALWSRVLPITFTAVGLIALVGGGLLASFSLRSESALTDPGLDRGDQDFFGRSGLEEPVSGAEAETEKLPTQRPDLRSESGPDEPTEAGPTEAKPPDRE
>NZ_CP040250.1|WP_033711070.1|631661_633359_+|hypothetical-protein
MRWTRPGYALVLALLVVGPLLRPGYLLLRDAVSTPRSYLSDTALGLTAAPRAAPQDFAVALASHLLDGGVVVKTLLLLGLWLAGWGAARLVALVLPGAGMPGEFVATTLAIWNPYVAERLLQGHWSLLVGYGCLPWVATAMLGLRTGGAGFFGLAFFIALAGLTPTGLLLAAAVALACVPVAGAGRRRWVCAAAAIGAAAVAALPWLVAAVTGAALPSHTPANRLGVEAFAPRAEPGLGTLTSLASLGGIWNADAVPGSRTTLFAVASAVVLLGVVAVGLPAVARRPAAVPLLVLAAAAVLIPAGLATGPGLRLLGAVVDAAPGVGVLRDGQKWVALAVPGYALAGAGAVLTLRRRLFGAAAPALVCCLALILALPDLVWGVGGRVSPVRYPRGWPAVAAAINARPDAVAVLPAGTMRLFSWSGPAPVLDPLPRWVRADVLSTGDLVISGTTIAGEGAHARAVQELLLSGPDPAALAAAGVGWLVLEADSAGEVGAAAHTLGAAAPVYRDDEIALYRIGGHTAGVAADRRAATLIAHLAWLVLLLGSGAGVLLGACRRRGVSRAR
>NZ_CP040250.1|WP_033711072.1|633342_634509_-|glycosyltransferase-family-4-protein
MSSLRSVLLLCWRDTGHPQGGGSEAYLQRIGAQLAAAGIAVTLRTARYPGAPRRDVVDGVRISRAGGRYSVYIWALLAMAVARLGLGPLRAVRPDVVVDTQNGLPFLARLIYGRRVVVLVHHCHREQWPVAGPVLGRLGWFVESTLSPRLNRRNQYVTVSLPSARDLVALGVDGTRIAVVRNGLDEAPAPSLSGPRAAAPRVVVLSRLVPHKQIEDALEAVARLRPRVPGLHLDIVGDGWWRQRLVEHVDRLGIGSAVTFHGHVDDVTKHHVLQGAWVHLLPSRKEGWGLAVVEAAQHRVPTIGYRSSGGLSDSIVDEVTGILVDTHAELVDRLEQLLADPVLRDQLGAKAHTRSGEFSWAQSADAMRGVLEAVQAGRTVSGLVSGRG
>NZ_CP040250.1|WP_019733639.1|634590_635358_+|class-I-SAM-dependent-methyltransferase
MAVTDIFARRATLARSVRLLSQFRYERSEPARFYGALAADTAAMVDDLWRAGHGESAAGRTLLDVGGGPGYFAAAFTDAGVRYLGVEPDPGEMHAAGPVVAADTGTFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLTHYLGGARAAARYARKHGHPAKNNYGSSLFEVSVADGLAWAASTGAALAAFPRYHPRWAWWLTSVPVLREFLVSNLVLVLQPQ
>NZ_CP040250.1|WP_009979657.1|635403_636885_+|aldehyde-dehydrogenase
MSDIQTQAKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKVPLAAAADVDAAVAAARAAFDNGPWPTTPPKERAAVIANALKVMEERKDLFTGLLAAETGQPPTSVETMHWMSSIGALNFFAGPAVDQVKWKEVRTGGYGQSIVHREPIGVVGAIVAWNVPLFLAVNKLGPALLAGCTVVLKPAAETPLSANALAEAFAEAGLPEGVLSVVPGGIETGQALTSNTDVDIFSFTGSSAVGREIGRRAADMLKPCTLELGGKSAAIVLDDVDLPSALPMLVFSGIMNSGQACVAQTRILAPRSRYDEIVDAVSTFVQSLPVGLPSDPAAQIGSLISEKQRARVEGYIAKGIEEGARLVCGGGRPEGLDSGFFVQPTVFADVDNKMTIAQEEIFGPVLSIIPYDTEEDAIKIANDSVYGLAGSVWTADVQRGIAVSEKIRTGTYAINWYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVLMPMGYTLEG
>NZ_CP040250.1|WP_003879120.1|637409_637997_+|TetR/AcrR-family-transcriptional-regulator
MLASAAEVMRERGAAGVTIDAVLARSGAPRGSVYYHFPDGRNQILAEALRYSGDSITALIDQAAGRGGRALLREFVEYWERLLTEGGFTAGCPVVAAAIGCSEDEGPKLSAEAGAILGRWCTALTRAFVNDGFDDADAASLAVMSIAALEGGIVLSRSTRNAGPLHQVGEQLEFLIKAREFVVRNKIPGKQPGSR
>NZ_CP040250.1|WP_003874076.1|637998_638295_-|hypothetical-protein
MIKNGTRLASQVCDTQVIVVRSADSLDDLRCGGVPMVPVGAERSGELDPSFADGTVMGKRYVDETGAEVLVTKPGAGSLSIGQTPLQLKEVKPLPASD

Crispr_ID: NZ_CP040250_2

• CRISPR_ID: NZ_CP040250_2
• CRISPR_location: 853926-854046
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040250_2

Consensus_repeat	Method
GCTGCAGATCCACGGCACCGCCGACGACCGGG	CRISPRCasFinder

spacers of NZ_CP040250_2

>2.1|853958|57|NZ_CP040250|CRISPRCasFinder
ATCGCCCCGGTGGCCGGCGTTGCTCACCGATTGCTCCGCGGCCCGGCCGGCCTCGGT

CRISPR arrays and Neighbor proteins around NZ_CP040250_2

CRISPR arrays

The CRISPR arrays of NZ_CP040250_2

>merge|NZ_CP040250|2|853926-854046|CRISPRCasFinder
GCTGCAGATCCACGGCACCGCCGACGACCGGGATCGCCCCGGTGGCCGGCGTTGCTCACCGATTGCTCCGCGGCCCGGCCGGCCTCGGTGCTGCAGATCCACGGCACCGCCGACGACCGGG

>NZ_CP040250|2|2|853926-854046|CRISPRCasFinder
GCTGCAGATCCACGGCACCGCCGACGACCGGG	ATCGCCCCGGTGGCCGGCGTTGCTCACCGATTGCTCCGCGGCCCGGCCGGCCTCGGT
GCTGCAGATCCACGGCACCGCCGACGACCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040250.1|WP_023860853.1|851869_852325_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP040250.1|WP_062886718.1|860740_861571_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP040250.1|WP_050483976.1|843038_844598_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224983
NZ_CP040250.1|WP_062887574.1|858414_858753_+|DUF3024-domain-containing-protein	unknown	unknown	gnl|CDD|371425
NZ_CP040250.1|WP_062886722.1|865148_866315_-|thiolase-family-protein	unknown	unknown	gnl|CDD|238425
NZ_CP040250.1|WP_062886720.1|862494_864135_+|AMP-binding-protein	unknown	unknown	gnl|CDD|237374
NZ_CP040250.1|WP_003874302.1|849406_850816_+|membrane-protein	unknown	unknown	gnl|CDD|223700
NZ_CP040250.1|WP_062886721.1|864073_864724_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378427
NZ_CP040250.1|WP_011726555.1|845286_845757_-|polyketide-cyclase	unknown	unknown	gnl|CDD|176867
NZ_CP040250.1|WP_003874307.1|859457_860018_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380066
NZ_CP040250.1|WP_009979912.1|851053_851863_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|213022
NZ_CP040250.1|WP_048424532.1|852806_853886_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP040250.1|WP_062886719.1|861646_862408_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP040250.1|WP_009979923.1|864720_865152_-|hypothetical-protein	unknown	unknown	gnl|CDD|366817
NZ_CP040250.1|WP_003874308.1|860060_860669_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP040250.1|WP_011726565.1|866304_866634_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_062886715.1|846982_849271_+|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783
NZ_CP040250.1|WP_033727441.1|844731_845286_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|274679
NZ_CP040250.1|WP_019732414.1|846773_846986_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|238219
NZ_CP040250.1|WP_011726556.1|845866_846688_+|mycofactocin-coupled-SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|274889

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040250.1|WP_023860853.1|851869_852325_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.90652e-15
NZ_CP040250.1|WP_062886718.1|860740_861571_+|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	6.17545e-20
NZ_CP040250.1|WP_050483976.1|843038_844598_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.83881e-94
NZ_CP040250.1|WP_062887574.1|858414_858753_+|DUF3024-domain-containing-protein	gnl|CDD|371425	pfam11225, DUF3024, Protein of unknown function (DUF3024). This family of proteins has no known function.	1.23698e-17
NZ_CP040250.1|WP_062886722.1|865148_866315_-|thiolase-family-protein	gnl|CDD|238425	cd00829, SCP-x_thiolase, Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.	1.40606e-94
NZ_CP040250.1|WP_062886720.1|862494_864135_+|AMP-binding-protein	gnl|CDD|237374	PRK13388, PRK13388, acyl-CoA synthetase; Provisional.	0
NZ_CP040250.1|WP_003874302.1|849406_850816_+|membrane-protein	gnl|CDD|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	2.26307e-11
NZ_CP040250.1|WP_062886721.1|864073_864724_-|MarR-family-transcriptional-regulator	gnl|CDD|378427	pfam10400, Vir_act_alpha_C, Virulence activator alpha C-term. This structure is homo-dimeric, and the domain here is the C-terminal half of the structure, often associated with PadR upstream, (pfam03551), which is a transcriptional regulator.	0.00272654
NZ_CP040250.1|WP_011726555.1|845286_845757_-|polyketide-cyclase	gnl|CDD|176867	cd07825, SRPBCC_7, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.2923e-57
NZ_CP040250.1|WP_003874307.1|859457_860018_+|TetR-family-transcriptional-regulator	gnl|CDD|380066	pfam17940, TetR_C_31, Tetracyclin repressor-like, C-terminal domain. This is the C-terminal domain found in putative transcriptional regulator, TetR family proteins.	1.71062e-06
NZ_CP040250.1|WP_009979912.1|851053_851863_+|polysaccharide-deacetylase-family-protein	gnl|CDD|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	3.80459e-36
NZ_CP040250.1|WP_048424532.1|852806_853886_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.08218e-14
NZ_CP040250.1|WP_062886719.1|861646_862408_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	8.57348e-46
NZ_CP040250.1|WP_009979923.1|864720_865152_-|hypothetical-protein	gnl|CDD|366817	pfam01796, OB_aCoA_assoc, DUF35 OB-fold domain, acyl-CoA-associated. The structure of a DUF35 representative reveals two long N-terminal helices followed by a rubredoxin-like zinc ribbon domain and a C-terminal OB fold domain represented in this entry. OB-folds are frequently found to bind nucleic acids suggesting this domain might bind to DNA or RNA (Topsan http://www.topsan.org/). Genomic context shows it to be adjacent to acyl-CoA transferase (http:/www.microbesonline.org/).	3.15097e-20
NZ_CP040250.1|WP_003874308.1|860060_860669_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.37413e-12
NZ_CP040250.1|WP_062886715.1|846982_849271_+|copper-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP040250.1|WP_033727441.1|844731_845286_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	8.99786e-20
NZ_CP040250.1|WP_019732414.1|846773_846986_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|238219	cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. In the case of copper, stoichiometry of binding is one Cu+ ion per binding domain. Repeats of the HMA domain in copper chaperone has been associated with Menkes/Wilson disease due to binding of multiple copper ions.	1.20367e-10
NZ_CP040250.1|WP_011726556.1|845866_846688_+|mycofactocin-coupled-SDR-family-oxidoreductase	gnl|CDD|274889	TIGR03971, short-chain_dehydrogenase/reductase_SDR, SDR family mycofactocin-dependent oxidoreductase. Members of this protein subfamily are putative oxidoreductases belonging to the larger SDR family. All members occur in genomes that encode a cassette for the biosynthesis of mycofactocin, a proposed electron carrier of a novel redox pool. Characterized members of this family are described as NDMA-dependent, meaning that a blue aniline dye serving as an artificial electron acceptor is required for members of this family to cycle in vitro, since the bound NAD residue is not exchangeable. See EC 1.1.99.36. [Unknown function, Enzymes of unknown specificity].	2.89068e-126

Protein sequences

>NZ_CP040250.1|WP_048424532.1|852806_853886_+|IS110-family-transposase
MTSMNHNRRRGRVVIGVDTHKHIHVAVALDDFGGVLGKEKFTADTAGYGQLIDWAMTHGHLLTFAIEGTGSYGAGLTAAVRRSDIGVVEVMRTDRRDRRLRGKSDFLDAENAARAVLAGHADAVPKTADGVVEMIRTIKVAKDVAVKARTSALISLKAVLVNAPAALREQLQPLSKMALIHRCAGLRPGSMTTVEAATKHTLRSIARRWEQLNDEITAHEKMLVELTTTLAPQLYAAFGVGADTAAEMLIVAGDNPERVRSEPAWARLCGVAPIPASSGMTTRHRLNRGGHRQANAALYRTVIVRMQHHEPTKTYVARRTAEGKTKAEIIRCLKRLLAREIWSLMRPLRTSPQTMKSAA
>NZ_CP040250.1|WP_023860853.1|851869_852325_-|MarR-family-transcriptional-regulator
MREGARGGWEPTVPALVNLVAAAGAPRLRAAFAEAGLDGIRPAQSLALVPLAAGGLHASDLADRLRVSRQAVAQAVAALERHGYVTRTPDPADARARIIELTPRGRQALQVMRANAIAMEKRWRKVLGERRLTELRETLTMLLAAEREPGG
>NZ_CP040250.1|WP_009979912.1|851053_851863_+|polysaccharide-deacetylase-family-protein
MNRRQFLGSLAASVVAGVGAARLIVDPQPRTFAQTPAAAIPTSGPTAPQALLPPPPLSARIPLPGGGALMKIPGEGDLLALTVDDGVNSEVVRAYTQFAKDTGVRLTYFVNGVYDSWTENLQLLRPLVDSGQIQLGNHTWSHPDLTTLTKEQVAEQLSRNDAFLKKTYGIGAKPYWRPPYAKRNATVDAVAADLGYQVPTLWSGSLSDSTLITEDYILQMADQYFTPQAIVIGHLNHLPVTHVYPQLVDIIRERNLRTVTLNDVFLKTP
>NZ_CP040250.1|WP_003874302.1|849406_850816_+|membrane-protein
MEQFFGQLSLLHGWLPPTVQGLALLMLVAAIHWRARGWLKRVLPAALVAAVAVTVLARWYITSLGVAGDPAPTALWLWIALSGLAAAVFLVGWRGVRWWRRGLAVLSIPLCVLCAGLALNGWVGYFPTVLAAWNQLTQAPLPDQIDRLRVTEMQIAGTRPSKGVVVPVDIDGNGPSGSHFAHRRELVYLPPAWFNSNPPPRLPAVMMISSAFNTPADWLGPGGAFTAIDNFAAAHHGFAPVLVFVDPTGSFDNDTECVNGSRGNAADHLTKDIQPFMVSNFGVSADRANWGVAGWSMGGTCAVDLAVMHPEMFRAFVDIAGDRGPNVGPKDQSVARLFGGDQAAWAAFDPVTVMTRHGRYADLSGWFEVPGADVARTAQQGNADPAPALVASSSDPAANPEGQDAAAHSLCAVGAANGIACAVVTQPGKHDWPFAAQAFATALPWLAWTIGTPNTEPVQLPQRAAAPPR
>NZ_CP040250.1|WP_062886715.1|846982_849271_+|copper-translocating-P-type-ATPase
MSTPPRHVDEGTFPDHTASTARIELEITGMTCASCAARIEKRLNKLDGVTATVNYATEKAAVSAPASYDPQTLITEIENAGYAAAVAKPSPPQDDPELASLRRRLVTATALAGPVIAVAMIPALQFQHWHWAALALTAPVVGWCGRPFHAAAWANLKHGVATMDTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALGAKDVAVLRAGAETRIPIERLAVGDEFVVRPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRLVVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAVATLAGWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQLGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGTDRATLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGTVDGHAVAVGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGILALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRIAGELGIGEVISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTDVAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLAALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA
>NZ_CP040250.1|WP_019732414.1|846773_846986_+|heavy-metal-associated-domain-containing-protein
MPTSEYQVSGMSCGHCEAAVHSEVARIPGVDAVSVSADTGRLVVTSAVPIDADAVLGAVDEAGFQAVLVA
>NZ_CP040250.1|WP_011726556.1|845866_846688_+|mycofactocin-coupled-SDR-family-oxidoreductase
MSQSLTGKVALITGAARGQGRAHAARLAAEGADIIAVDLAGPLPPSVPYDSSTPEDLAATAELVRAAGRRVVTAQTDVRDLDALTSSVDRAVGELGRLDVIVANAGICSPAPWNRITAQAFRDTIDTNVVGTWNTVMAGAQHIIDGGRGGSIILIGSAAGINMQSFMVHYTASKHAVVGMARAFAAELGRYNIRVNSLNPGAVATPMGTGRMRDALRAAADDYPHLRGLHKPLLPEGIAQPEDIADAVAWLASDQSRLVTASQVSVDLGVGYV
>NZ_CP040250.1|WP_011726555.1|845286_845757_-|polyketide-cyclase
MTVTVVDRGPRQVSRRVDVAAPAAQLYALVADPRRHHELDGSGTVRDNISVPAKLVEGSKFSTHMRMFGLPYRITSTITELKPNEVVEWRHPLGHRWRWEFESLSPTRTRVTETFDYRDAGALKNRLKYYERMGFAKANASGIEATLAKLRDRYPG
>NZ_CP040250.1|WP_033727441.1|844731_845286_+|pyridoxamine-5'-phosphate-oxidase
MLLPLAAEPFTAPTDRDMLPSERREFVRTHRTCVFGYRRRNDGPAMSIVYYIPTDTGELLVSTMAGRGKARVVQRDPKVSLCILDERWPFSYLQVYADAALDEDRELAVDVMMAVAGRMSGQPLGDEARPHVRDICERENRVVIRCRPYGTFATPPRHLHRNDQVQELSHWVSGVIPWDAADPD
>NZ_CP040250.1|WP_050483976.1|843038_844598_-|NAD(P)/FAD-dependent-oxidoreductase
MMSGKAKWLYAIGRVRAATRRRRGPKVAIIGAGFGGLGAAVALRRAGIDDLVIIEAADGVGGTWRRNTYPGAACDIQSHLYSFSFAPNASWSRTYARQPEILAYLESVADAFDLRRHLMLDTTVRSLRWNPHTAAWDCRIDRGGHPATLSADVVVCAVGLFGAAKLPDIDGLAGFAGPVLHTAQWDHDLDLAGRTVAVIGTGASGVQLVPELAGTAGHVTVFQRTPPWMVPKDDRPYSATELARFKRNPLALRRTRWQIWKFQHDNTATFADDPVVTARSRIATSFLDRTVADESLRRALTPDYPFRCKRVLLGDDYYRALQRDNVELVTDPIARIGRRSVITASGAEIEADVIVLATGFKTSRYLSGIEVVGAGGRRLHEHWGEEPSAYLGVAVSGFPNFFMLYGPNTNQGGNSIVYILEAGARLVASAVSRLARRGGCLEVRPEAEKRFNDRLSADLERTIWTRCDSYFRSPTGRIVTQWPYTELDYARWTWRLRRRDWIHHRCAPSAATVGAAQEF
>NZ_CP040250.1|WP_062887574.1|858414_858753_+|DUF3024-domain-containing-protein
MALPELDIARVQQWCAARVPEHARHQVRVECDVAARHLTIVERRAPWREDYGPDWTSFPIARLRYTATTNTWTLYWRDRHLKFHRYDTIDPTPHIHDVLTEIDHNPSGIFWG
>NZ_CP040250.1|WP_003874307.1|859457_860018_+|TetR-family-transcriptional-regulator
MLGGNGLHGVSHPKVDDRAGVPAGTTSFYFRTRKALVHAMAGRLAELDVADFSMMAELAEDHATEFAGTAGLARIVMYVNSEPWLTRAKARYELALLAGRDPELAAALSESADRLYALARNVVTQWHPAGSAPDPALVDDQATATLAFINGIMLTFVAGQPAVDDAGQLDRLIQGVIAGVAHVRGA
>NZ_CP040250.1|WP_003874308.1|860060_860669_-|TetR/AcrR-family-transcriptional-regulator
MESKRRTQEERSAATRDALIAAARKLWGLRGYTEVGTPEIAAAAGVTRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDAIRAAVDAWLEVSADPEVRQLILLDAPSVLGWAEFRDVAQRYSLGMTEQLLTEAIRAGELAEQPVRPLAHVLIGALDEAAMVIATADDPDRARRETRQVLQRLVDGMFDAR
>NZ_CP040250.1|WP_062886718.1|860740_861571_+|alpha/beta-hydrolase
MSTIDISAGTIHYEATGPADGRPVVFVHGYLMGGQLWRQVSDRLAGRGLRCIAPTWPMGAHPEPLRPGADRTITGVAAMVAELLSALDLEDVVLVGNDTGGVVSQLVAVHHRERLGALVLTSCDAFEHFPPPVLRPVILAAKSKATFRAVAQAMRAPAVRKRAFDGLAHSNIDALTELWVRPALSLPAVAEDLRRFTLSLRTEVTTAAASRLYDFDKPTLIAWSADDVFFAQEDGARLAATIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT
>NZ_CP040250.1|WP_062886719.1|861646_862408_+|SDR-family-oxidoreductase
MTDELRGRRILVTGAATGIGAAAVSVLTDAGADVVATYHTTPPPPDLTAHWLQCDARDADAVSALVHRAAEHLGGLDVLVHAAGLWQPGIPGCIGADDISFLLDTNVKATILTNQAAHAAMKAQDPQGGRIINFGSSEAVMGSPISAVYAATKGAVQAWTRSAAKAWAADHVTVNALAPAVQTPGADRLRAFLGPDAAALIDQQMQMMIPLGGALGEPARDLGPMLVFLAGAGSGFITGQLLAVDGGLMMVGG
>NZ_CP040250.1|WP_062886720.1|862494_864135_+|AMP-binding-protein
MAEDTIQALLRKRWSDPGVAVKYGDTQWSWAQYLRDAAARAAALLDAADPGRPMHVGTLLGNTPEMLSQMAAAGLGGYVLCGLNTTRRGEALAADVRRADCQFVVTDAEHRPLLDGLDLAGTQILDTSTPDWAGFVDAAGELTPHREVAAMDPFMMIFTSGTSGNPKAVQVSHLMAVFAGSNLVQRFGLTEHDTCYVSMPLFHSNAVVAGWAPAVCSGAAIVPAKFSARNFLDDIRRYGATYMNYVGKPLAYVLATPERADDADNPLRVAFGNEANDKDIEEFGRRFGVQVEDGFGSTENAVIVIREPGTPRGSIGRGIDGVAIYNSDTVTECPVARFDADGALINADEAVGELVNTAGSGFFTGYYNDPDANAERMRHGMYWSGDLAYRDADGWIYLAGRTADWMRVDGENLAAAPIERILLRHSAINRVAVYAVPDGHVGDQVIAAVVLNDGETLTPAAFEAFLDAQPDLSPKARPRYVRIAADLPSTATHKVLKRQLISQGTAVAAGEVLWEREPRGTAYTVVASPDCGVPGDGSAPSTVAPV
>NZ_CP040250.1|WP_062886721.1|864073_864724_-|MarR-family-transcriptional-regulator
MSPRTSNGLPVTAYLVLGVLAANDERLTAGEIKTRAELSVGHFYWSPSVSHVRRELTRLLARGMVAQTGTQSGKRAITLYETTDAGRDALRRWVQHFPGQDQVVIKHPVILKTWLARGEDPERIVDTLERHLDATRARLDEALWSRRRSQELGITEDPEQRFSFAVLDYAIRGLYAEISNISQLRDEIAGGTSRDPVKRVRRSKGQIRRRAPRSPG
>NZ_CP040250.1|WP_009979923.1|864720_865152_-|hypothetical-protein
MTAEPLRPQTGPVPHASSPLSVPFWEGCRSRQLRYQRCRACDLANFPPTEHCRQCLSDDIGWQQSGGRGEIYSWTVVHRPVTAEFTPPYAPAIITLDEGYQMLTNVVGVPPGDLRVGLRVRVQFHTVAADVTLPYFTAETDGS
>NZ_CP040250.1|WP_062886722.1|865148_866315_-|thiolase-family-protein
MKTRPAKRTAAIVGVHNTRQGRRLDGETSRSLALKAIRGALDDAGLCLDDVDGISAGPLSTALIYDLRLGPAWQGLGFGVGMITEAATAIEHGMAEVVVLVAAQAGEYRDHEATAPWTRPENEFVAPWGMFTTAEFALIARRHMHVYGTTREHLSTVAATIRNNGSRNPEAVYYQRGPFTPADITASRPIADPFHLLDCATTSEGGCALVLANLEKVDTASQPIYVLGSGADFHGPSYQHPPAYDLAGRRGGDVNGVVGRRAADCAFAHAGLRRDDVDVLELYDPFSFEIIRQLEAFGFCGDGEGGPFVADGHIALDGSHPVTTDGGTMSFSHAGSNPQMMQRAIRAVQQLRGQAGELQVPDAHIALCSNGGAGALFTTVLILGDEPR
>NZ_CP040250.1|WP_011726565.1|866304_866634_-|hypothetical-protein
MAVSLCVPPRAGELCAAVRFLVRRDSVVIELTARHRITGVEWDPDERAVAMVVEITDPQTARPVDVRIDVLAKGAPRADSRCTLIGEIDRDGTRFDVVGTYLGVVADEN

Crispr_ID: NZ_CP040250_3

• CRISPR_ID: NZ_CP040250_3
• CRISPR_location: 2179126-2179369
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP040250_3

Consensus_repeat	Method
GCGGCGGGTGCCGGAGCGGACGGCG	CRISPRCasFinder

spacers of NZ_CP040250_3

>3.1|2179151|20|NZ_CP040250|CRISPRCasFinder
GTGCGCCCGGGGTTGCCGGG
>3.2|2179196|47|NZ_CP040250|CRISPRCasFinder
GCGGAACCGGTGCGGCGGCCGGGACGGTGGCCGGCTGAACCGGCCCG
>3.3|2179268|17|NZ_CP040250|CRISPRCasFinder
GAGCGGACGGCGGGGTG
>3.4|2179310|35|NZ_CP040250|CRISPRCasFinder
GGGTGGCGGCGGGTGCCGGAGCCGACGGCGCAGCG

CRISPR arrays and Neighbor proteins around NZ_CP040250_3

CRISPR arrays

The CRISPR arrays of NZ_CP040250_3

>merge|NZ_CP040250|3|2179126-2179369|CRISPRCasFinder
GCCGCGGGGGCCGGCGCGGCGTCGGGTGCGCCCGGGGTTGCCGGGGCCGCGGCGGCCGGCGCCGGTGGCGGCGGAACCGGTGCGGCGGCCGGGACGGTGGCCGGCTGAACCGGCCCGGGCGCGGGAGCCGCGGCGGGTGCCGGAGCGGACGGCGGGGTGGCGGCGGGTGCCGGAGCCGACGGCGGGGTGGCGGCGGGTGCCGGAGCCGACGGCGCAGCGGCGGCGGGTGCCGGGCCGGCCGCGT

>NZ_CP040250|3|3|2179126-2179369|CRISPRCasFinder
GCCGCGGGGGCCGGCGCGGCGTCGG	GTGCGCCCGGGGTTGCCGGG
GCCGCGGCGGCCGGCGCCGGTGGCG	GCGGAACCGGTGCGGCGGCCGGGACGGTGGCCGGCTGAACCGGCCCG
GGCGCGGGAGCCGCGGCGGGTGCCG	GAGCGGACGGCGGGGTG
GCGGCGGGTGCCGGAGCCGACGGCG	GGGTGGCGGCGGGTGCCGGAGCCGACGGCGCAGCG
GCGGCGGGTGCCGGGCCGGCCGCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040250.1|WP_085979723.1|2179852_2180443_-|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NZ_CP040250.1|WP_095884648.1|2191140_2193039_+|translational-GTPase-TypA	unknown	unknown	gnl|CDD|224138
NZ_CP040250.1|WP_085978475.1|2176394_2176919_-|DUF1697-domain-containing-protein	unknown	unknown	gnl|CDD|226319
NZ_CP040250.1|WP_003875447.1|2178485_2178632_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_023861250.1|2177881_2178457_+|(Fe-S)-cluster-assembly-protein	unknown	unknown	gnl|CDD|132296
NZ_CP040250.1|WP_023861249.1|2177495_2177720_+|DUF5302-domain-containing-protein	unknown	unknown	gnl|CDD|379949
NZ_CP040250.1|WP_003875444.1|2176993_2177437_+|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274679
NZ_CP040250.1|WP_033711794.1|2184263_2187956_+|nitrate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|227346
NZ_CP040250.1|WP_003875457.1|2189570_2190254_+|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl|CDD|225091
NZ_CP040250.1|WP_023861247.1|2175977_2176343_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224639
NZ_CP040250.1|WP_023861252.1|2180688_2182002_+|mannosyltransferase	unknown	unknown	gnl|CDD|172015
NZ_CP040250.1|WP_009975493.1|2182509_2183283_-|cell-division-protein-DivIVA	unknown	unknown	gnl|CDD|274008
NZ_CP040250.1|WP_023861244.1|2172158_2174501_+|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP040250.1|WP_009975471.1|2174583_2175219_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP040250.1|WP_003875456.1|2187957_2189574_+|nitrate-reductase-subunit-beta	unknown	unknown	gnl|CDD|224063
NZ_CP040250.1|WP_023861246.1|2175226_2175940_-|NAD-dependent-deacylase	unknown	unknown	gnl|CDD|234777
NZ_CP040250.1|WP_062888070.1|2183452_2183845_+|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|239517
NZ_CP040250.1|WP_099459250.1|2171814_2172015_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_011724058.1|2182094_2182379_-|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl|CDD|234845
NZ_CP040250.1|WP_044543576.1|2190246_2190978_+|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl|CDD|376889

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040250.1|WP_085979723.1|2179852_2180443_-|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	1.456e-06
NZ_CP040250.1|WP_095884648.1|2191140_2193039_+|translational-GTPase-TypA	gnl|CDD|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NZ_CP040250.1|WP_085978475.1|2176394_2176919_-|DUF1697-domain-containing-protein	gnl|CDD|226319	COG3797, COG3797, Uncharacterized protein conserved in bacteria [Function unknown].	1.07856e-57
NZ_CP040250.1|WP_023861246.1|2175226_2175940_-|NAD-dependent-deacylase	gnl|CDD|234777	PRK00481, PRK00481, NAD-dependent deacetylase; Provisional.	1.07168e-117
NZ_CP040250.1|WP_023861250.1|2177881_2178457_+|(Fe-S)-cluster-assembly-protein	gnl|CDD|132296	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein. This model describes a small, well-conserved bacterial protein family. Its sequence largely consists of a domain, HhH-GPD, found in a variety of related base excision DNA repair enzymes (see pfam00730). [DNA metabolism, DNA replication, recombination, and repair].	1.75425e-105
NZ_CP040250.1|WP_023861249.1|2177495_2177720_+|DUF5302-domain-containing-protein	gnl|CDD|379949	pfam17227, DUF5302, Family of unknown function (DUF5302). Family of unknown function found in Actinobacteria with highly conserved motif of FRRKSG found at the C-terminus.	1.8842e-12
NZ_CP040250.1|WP_003875444.1|2176993_2177437_+|PPOX-class-F420-dependent-oxidoreductase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	2.337e-41
NZ_CP040250.1|WP_033711794.1|2184263_2187956_+|nitrate-reductase-subunit-alpha	gnl|CDD|227346	COG5013, NarG, Nitrate reductase alpha subunit [Energy production and conversion].	0
NZ_CP040250.1|WP_003875457.1|2189570_2190254_+|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl|CDD|225091	COG2180, NarJ, Nitrate reductase delta subunit [Energy production and conversion].	1.16646e-55
NZ_CP040250.1|WP_023861247.1|2175977_2176343_+|GntR-family-transcriptional-regulator	gnl|CDD|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.32706e-35
NZ_CP040250.1|WP_023861252.1|2180688_2182002_+|mannosyltransferase	gnl|CDD|172015	PRK13375, pimE, mannosyltransferase; Provisional.	0
NZ_CP040250.1|WP_009975493.1|2182509_2183283_-|cell-division-protein-DivIVA	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	1.53833e-06
NZ_CP040250.1|WP_023861244.1|2172158_2174501_+|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.38283e-127
NZ_CP040250.1|WP_009975471.1|2174583_2175219_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	8.49915e-15
NZ_CP040250.1|WP_003875456.1|2187957_2189574_+|nitrate-reductase-subunit-beta	gnl|CDD|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
NZ_CP040250.1|WP_062888070.1|2183452_2183845_+|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	7.9879e-36
NZ_CP040250.1|WP_011724058.1|2182094_2182379_-|4a-hydroxytetrahydrobiopterin-dehydratase	gnl|CDD|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	1.7316e-40
NZ_CP040250.1|WP_044543576.1|2190246_2190978_+|respiratory-nitrate-reductase-subunit-gamma	gnl|CDD|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	7.05622e-109

Protein sequences

>NZ_CP040250.1|WP_003875447.1|2178485_2178632_+|hypothetical-protein
MKTHITCPCGEAIVGKDEDELVELTQAHLASVHPGLEYDRDAILFMAY
>NZ_CP040250.1|WP_023861250.1|2177881_2178457_+|(Fe-S)-cluster-assembly-protein
MPKLQLVQEPAADALLDENPFALLVGMLLDQQVPIETAFAGPKKIADRMGRLDAATIADYDPDKFAALCSERPAIHRFPGSMAKRIQALAQLLVDRYDGDAAALWTAGEPDGKELLRRLKGLPGFGEQKARIFLALLGKQYGVTPPGWREAAGEFGKAGTYLSVADIVDARSLGQVRSYKKQMKAAAKAAK
>NZ_CP040250.1|WP_023861249.1|2177495_2177720_+|DUF5302-domain-containing-protein
MVASSARQGSTSSKSSGGAGSSKSDDDTKRRFREALDRKMAKSTGGSEHKDGAGKQSRAHGPVESRREFRRKSG
>NZ_CP040250.1|WP_003875444.1|2176993_2177437_+|PPOX-class-F420-dependent-oxidoreductase
MGRQVFDDKLLAVISGNSLGVLATIKRDGRPQLSNVQYHFDPRSLVIQVSITEPRAKTRNLRRDPRASILVDADDGWSYAVAEGTAELTPPAAAPDDDTVQGLIALYRNIAGEHPDWDEYRQAMVTDRRVLLTLPISHVYGMPPGMR
>NZ_CP040250.1|WP_085978475.1|2176394_2176919_-|DUF1697-domain-containing-protein
MTEYAAFLRGVNVGGVNLKMADVKKALTDAGFTAVRTVLASGNVLLQSKAGAAAVRAKAEAALRERFGYDAWVLVYDLDTVRRVVDGYPFEREVDGYQSYVTFVADAAVLDELAALPAGPDERIRRGPDPLGVLYWQVPKGSTLDSTIGKTMGKPRYKSSTTTRNLRTLVKVLS
>NZ_CP040250.1|WP_023861247.1|2175977_2176343_+|GntR-family-transcriptional-regulator
MELGDRLRVDMKAGKPLFDQLRTQVIEGVREGALPPGTRLPTVRELAGQLGVAVNTVARAYRELESAAIIETRGRFGTFVARYDPTDAAMAAAAREYVRVARGLGLDKADAVRYIESVPDE
>NZ_CP040250.1|WP_023861246.1|2175226_2175940_-|NAD-dependent-deacylase
MRIAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLVADVAPNAGHRAIAAWQDHAEVSVITQNVDDLHERAGSRPVHHLHGSLFQFRCARCAKPYTGELPAMAEPALEVQPPVCGCGGLIRPDIVWFGEQLPDEPWRRAVEATESADVMVVVGTSAIVYPAAGLAELALSRGAAVVEVNPEVTPLSASATLSIRETASQALPRLLQRLPALLN
>NZ_CP040250.1|WP_009975471.1|2174583_2175219_+|class-I-SAM-dependent-methyltransferase
MTTVVVDNPFFARIWPVVATHETAAVRALRRENVAGLTGRVLEVGAGIGTNFPLYPETVDEVIAVEPEPRLADRARAAAQVVPVRVVVTGETAEAVGGDEPFDAVVCSLVLCSVRDPQNVLRRLYSLLRPGGQLRYLEHIASAGARGRFQRFVDATLWPRLFGNCHTHRDTERSIVEAGFDVDASRREWTLPAWSPMPVSELLLGRAHRPA
>NZ_CP040250.1|WP_023861244.1|2172158_2174501_+|MMPL-family-transporter
MLQKIARVAIAAPRRIIALGVLVFLAAAVFGIPVAKSLSPGGFQDPDSESARAIGVLTDKFGQSGQQMLILVTAPGGSNSDPARRVGTELVEQLQRSPLVYNVSSPWTAPPQASADLVSRDGKSGLIVVNLKGGENFVQNNAQTLADQFVHDRDGVTVRAGGAAMQYAQINTQNQADLLVMEMIALPLSFLVLIWVFGGLLAAALPMALGALAVVGSMSVLRLITFTTEVSIFALNLSTALGLALAIDYTLLIVSRYRDELAEGHDRDQALIRTMATSGRTVLFSAVTVALSMSATVAFPMYFLKSFAYAGVATVAFVATASIVITPAAIVLLGDRLDALDVRRLLRRALRRAQPVRKPVEQLFWYRSSKFVMRRWAPVGLIVVGLLLLLGLPFFSVKWGFPDDRVLPRSASAHQVGDRLRSGFAHDSATSVPVVIPDAAGLSPADLDDYAAALSRVPDVSAVSAPGGTFTGGTRVGPPAGATGLGDGSAFLTVSSTAPLFSTANDVQLKRLHEVPGPAGRSVEMGGVAQVNRDSVDAVTDRLPLVLGLMAAITFVLLFLLTGSVLLPAKALACNFLSLTAAFGALVWIFQDGHLGALGTTPSGTLVANMPVLLFCIAFGLSMDYEVFLLSRIREYWLASGAARPARPTPKRAHAANDESVALGVARTGRVITAAALVMSMSFAALIAAHVSFMRMFGLGLTLAVFADATLVRMVVVPAFMHVMGRWNWWAPKPLAWLHDRFGISEAADEEPRLAEPALGPVGSVGLPGGAVAEPVPNIG
>NZ_CP040250.1|WP_099459250.1|2171814_2172015_+|hypothetical-protein
MTSALVSSIHMTLSVWATIKESLSHDSENVGNLLPGRFAAVSAAKCAVSCLIAAYFSERTLTVEQV
>NZ_CP040250.1|WP_085979723.1|2179852_2180443_-|hypothetical-protein
MPNIPQQLISSAANAPQILQNLATALGATPPAPPATPGISFPGVPAAGSPVTASSPAAVPSIPGLPQAAAPSAPSTATGGIPGMIQGLTGAQPSAAAPAAPASSSIPGLPAIPGLSAPAAPATPPAPQLPQAQVNMPAMPAGLPVSVPAQVTLPKDLPALASGQAPGAPAAPAAPAAPAPAASPAGPVAPLLAALP
>NZ_CP040250.1|WP_023861252.1|2180688_2182002_+|mannosyltransferase
MKTGHLGTEATAARAPIAKVGRIDTTSAAPAAPSTRRAADVLAVAAPLLLVASVAARLAWTYLVPNGANFVDLHVYLGGAAALDHPGTLYSYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGLVALGWQLATIAALYGAVRISQRLLGVPAGAHGRRVAMVWTAVTIWIEPLRSTFDYGQVNVLLMTAVLWAVYSTRWWVSGLLVGLAAGIKLTPAVSGVYLAGARRWAATVFSAVIFLATIGISVLVVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLVTAVAGTAVLAVLAWRALDRSDRLGRLIVVEVFGLLLSPISWTHHWVWLVPLMIWAIHGPVRAWRGARLVGWGWLALTLIGVPWLLSFAQPNIWQIGRPWYLAWAGLVYIVAAVATLIWIAAAGRRAGHQVTAPSVTPA
>NZ_CP040250.1|WP_011724058.1|2182094_2182379_-|4a-hydroxytetrahydrobiopterin-dehydratase
MAVLTDEQIDAALPDLDGWERADGALRRSIKFPSFLDGIDAVRRVAEHAESKDHHPDIDIRWRTVTFALVTHSEGGITQNDVDMARDINGIVGS
>NZ_CP040250.1|WP_009975493.1|2182509_2183283_-|cell-division-protein-DivIVA
MITEPATAFSRVFRGYDPAAVDAYVEALLAKQKLLIDEVQNLRAQRNESGDQLAALRIEVACLKDEVAHLSDTSPTPYAIQHRMTKMLRRTLEEISRMQAEAQAEAESMIAAAAAQVEASHREHQELLADMAAQREALETEREEAKKDLEAELATMRAEAQAAIDEARQEAERECARLLAEAKQKADDLDERARRTVEEANQQRIMILEELMDVARDLQGLPASLESAYQERTSPSEASVVVPLDPKNQAPGPAVAS
>NZ_CP040250.1|WP_062888070.1|2183452_2183845_+|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase
MPTQIVVAGALIRGSRLLVAQRARPPELAGRWELPGGKVAPGETERDALARELAEELDLRVGDIAVGDRLGGDIAVDGGMTLRAYRVRLLRGRPDARDHRALRWITAAQLHDLDWVPADRGWLSDLARVL
>NZ_CP040250.1|WP_033711794.1|2184263_2187956_+|nitrate-reductase-subunit-alpha
MTATPHVGGVLEELLERSGRFFTPGEFSADLRTVTRQGGREADVFYRDRWSHDKVVRSTHGVNCTGSCSWKIYVKDGIITWETQQTDYPSVGPDRPEYEPRGCPRGASFSWYSYSPTRVRYPYARGVLVEMYREAKARLGDPVLAWADIQADPERRRRYQRARGKGGLVRITWAEATELIAAAHVHTIKTYGPDRVAGFSPIPAMSMVSYTAGSRFFELIGAPMTSFYDWYADLPVASPQVFGDQTDVPESGDWWDAAYLMMWGSNVPITRTPDAHWMAEARYRGTKVVTVSPDYADNTKFADEWMPCAAGTDGALAMAMGHVILSECYVQEQVPFFTDYARRYTDLPFLIKLEERGDMLVPGKNLTAADLGEAVENAALKPALLDETTNSVAVPHGSLGFRYGESGVGKWNLDLGDLVPALSVRAAPTEDGETALVHLPSFDTVDGEGKSVARGVPVRRVGKHLVCTVFDLMLAQYGVERPGLPGQWPTGYDDATQQNTPAWQEAITGVSAAQAIRVAREFARSAEESGGRSMIIMGGGICHWFHSDAIYRAVLALLMLTGSMGRNGGGWAHYVGQEKVRPLTGFQTMAMATDWVRPPRQVPGASYWYAHTDQWRYDGCGADKLASPVGRGRFAGRHTMDLLASAVAMGWSPYYPQFDRSSLDVADEARAAGRDVAEYVAEQLGRRNLKLAVTDPDNPVNWPRVLTVWRANLIGSSGKGGEYFLRHLLGTDSNASAVPPEDGVRPVDVTCEGDIPEGKLDLMMSIDFRMTSTTLVSDVVLPAATWYEKADISSTDMHPYVHAFSAATDPPWETRSDFDAFGAIARAFSTMAKEHLGTRTDVVLTALQHDTPDAMAYPDGAEHDWLRSGATPVPGRTMGKLTVVERDYAAVYDKWRTLGPLVDKFGLTTKGVTVHPFREVEELAARFGVLKSGVAAGRPAITTAARMADVLLLLSGTTNGRLAVEGFHELEKRTGQRLVHLAEGSEDKRISYADTQARPVPVVTSPEWSGSETGGRRYAPFTINIENLKPFHTLTGRMHFYLAHDWVEELGEHLPVFRPPLDMARLFGQPRLGACEDGIGLTVRYLTPHSKWSFHSTYQDNLYMLSLSRGGPTMWMSPGDAAKIQVRDNDWVEAVNANGIYVCRAIVSHRMPDGVVYVYHVQERTVDTPRTETNDKRGGNHNALTRVRIKPSHLAGGYAQHAFAFNYLGPTGNQRDEVTIVRRRSQEVVY
>NZ_CP040250.1|WP_003875456.1|2187957_2189574_+|nitrate-reductase-subunit-beta
MKVMAQLAMVMNLDKCIGCHTCSVTCKQAWTNRSGTEYVWFNNVETRPGQGYPRTYEDQERWRGGWIRDKRGRLRLRDGGRFQKLLRIFANPKLPVIGDYYEPWTYDYENLTTAPAGDTFPTAAPKSLISGEPMKVSWGPNWDDNLAGSPEILAEDPILKKVSEEVKLSLEQTFMFYLPRICEHCLNPSCVASCPSGAMYKRSEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYPRMEVGLPTICSETCVGRLRYLGVVLYDMDRVLEAASVENDTDLYRAQCDILLDPNDTDVIAGARAQGIPDEWIEAAQRSPVYALIHTYRVALPLHPEYRTMPMVWYIPPLSPVVDAVSRDGHDGEDLGNLFGALDALRIPMQYLAELFTAGDTAVVEGVLRRLAAMRSYMRDINLGRETQPHIPHSVGMTEEQIYEMYRLLAIAKYEERYVIPTAFAPQARDLEQMGCSLTGDGGPGMYESEPVAVETFHALKQRGGPTEAEPGSTRPRVNLLNWDGGQVPAGMFPEAQRR
>NZ_CP040250.1|WP_003875457.1|2189570_2190254_+|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MRLLSALRERSSSRVMQDRLVWQAASLLLAYPDDGFGGRLDTVEELLGHVSGPAGTLLGQTAAALRGREPMAAAMDYVATFDMRRRATMYLTYWTAGDTRNRGREMLAFATAYREAGVQPPSNEAPDHLTVVLEFAATVDPDAGRRLLIAHRVPIDVLRCALADAKSPYEPAVAAVCQTLPAATDQEARRAERLARQLLEAGPPAEAVGLQPFTLTVPPRAEGTPGV
>NZ_CP040250.1|WP_044543576.1|2190246_2190978_+|respiratory-nitrate-reductase-subunit-gamma
MFSNVLFWDISPYVTLSVLIVGTWWRYRYDKFGWTSRSSQIYESRLLSIASPIFHFGILAVFAGHVMGLFIPPRVTHMLKMSDHLYHMQAVIAGSAAGFATLAGVGLLIYRRFTRPAVSAATTRSDKVMYMVLVLAIVVGLYCDLIGTGPHGGEFHYRYTVGLWFRRIWILQPHGEVMVNAPLDYQLHALIGMVLFTLWPFTRLVHVFSAPVVYLFRPYIVYRSREVAAKDQLVGTAPRRRGW
>NZ_CP040250.1|WP_095884648.1|2191140_2193039_+|translational-GTPase-TypA
MSDVPFRNVAIVAHVDHGKTTLVDAMLRQSGALHHRGDDTQERILDSGDLEKEKGITILAKNTAVHRHHPDGSVTVINVIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAAHLPVILVVNKTDRPDARIAEVVEASHDLLLDVASDLDDEAAKAAEHALGLPTLYASGRAGVASTEQPADGEVPAGANLDPLFDVLLEHIPAPSGDPEAPLQALVTNLDASTFLGRLALIRIYNGKLRKGQQVAWMREVDGLPVITSAKITELLATEGVERSPTDEAIAGDIVAVAGLPEIMIGDTLADPDHAHALPRITVDEPAISVTIGTNTSPLAGKVPGHKLTARLVRNRLDQELVGNVSIRVVDIGRPDAWEVQGRGELALAVLVEQMRREGFELTVGKPQVVTRTIDGQLHEPFEAMTIDCPEEFVGAITQLMAARKGRMEEMTNHAAGWVRMDFIVPSRGLIGFRTDFLTITRGTGIANAVFDGYRPWAGEIRARHTGSLVSDRAGTITPFAMIQLADRGQFFVEPGQDTYEGMVVGINPRAEDLDINVTREKKLTNMRSSTADVIETLAKPLELDLEQAMEFCAADECVEVTPEIVRVRKVELDATSRARSRARAKARG

Crispr_ID: NZ_CP040250_4

• CRISPR_ID: NZ_CP040250_4
• CRISPR_location: 2508341-2508419
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040250_4

Consensus_repeat	Method
ATCAATTGCGCCACTCCTTTTCATCGC	CRISPRCasFinder

spacers of NZ_CP040250_4

>4.1|2508368|25|NZ_CP040250|CRISPRCasFinder
TGCGCTCTGCATCGTCGTGGCGCGT

CRISPR arrays and Neighbor proteins around NZ_CP040250_4

CRISPR arrays

The CRISPR arrays of NZ_CP040250_4

>merge|NZ_CP040250|4|2508341-2508419|CRISPRCasFinder
ATCAATTGCGCCACTCCTTTTCATCGCTGCGCTCTGCATCGTCGTGGCGCGTATCAATTGCGCCACTCCTTTTCATCGC

>NZ_CP040250|4|4|2508341-2508419|CRISPRCasFinder
ATCAATTGCGCCACTCCTTTTCATCGC	TGCGCTCTGCATCGTCGTGGCGCGT
ATCAATTGCGCCACTCCTTTTCATCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040250.1|WP_009977607.1|2498456_2499242_+|triose-phosphate-isomerase	unknown	unknown	gnl|CDD|234589
NZ_CP040250.1|WP_019732674.1|2505294_2506224_-|histone-deacetylase-family-protein	unknown	unknown	gnl|CDD|212541
NZ_CP040250.1|WP_137987534.1|2497212_2498460_+|phosphoglycerate-kinase	unknown	unknown	gnl|CDD|234613
NZ_CP040250.1|WP_033718259.1|2517273_2518053_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|272861
NZ_CP040250.1|WP_003876065.1|2506242_2506641_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_033720734.1|2500544_2503352_+|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|234570
NZ_CP040250.1|WP_019732679.1|2514563_2515538_-|quinone-oxidoreductase	unknown	unknown	gnl|CDD|176189
NZ_CP040250.1|WP_033710672.1|2499523_2500441_-|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274651
NZ_CP040250.1|WP_042906634.1|2509966_2511088_-|transaldolase	unknown	unknown	gnl|CDD|235117
NZ_CP040250.1|WP_019732673.1|2504306_2505293_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381310
NZ_CP040250.1|WP_033710634.1|2513460_2514387_+|protoheme-IX-farnesyltransferase	unknown	unknown	gnl|CDD|235293
NZ_CP040250.1|WP_137987536.1|2518981_2520685_-|hypothetical-protein	unknown	unknown	gnl|CDD|274589
NZ_CP040250.1|WP_019732672.1|2503427_2504207_+|DUF4239-domain-containing-protein	unknown	unknown	gnl|CDD|372881
NZ_CP040250.1|WP_023863986.1|2511104_2513204_-|transketolase	unknown	unknown	gnl|CDD|223100
NZ_CP040250.1|WP_019732675.1|2506681_2507437_-|6-phosphogluconolactonase	unknown	unknown	gnl|CDD|376480
NZ_CP040250.1|WP_003877656.1|2518049_2518958_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP040250.1|WP_023900055.1|2508425_2509970_-|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NZ_CP040250.1|WP_033710637.1|2515557_2516196_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_003876059.1|2499272_2499506_+|preprotein-translocase-subunit-SecG	unknown	unknown	gnl|CDD|235881
NZ_CP040250.1|WP_137987535.1|2516145_2517099_-|heme-A-synthase	unknown	unknown	gnl|CDD|224528

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040250.1|WP_009977607.1|2498456_2499242_+|triose-phosphate-isomerase	gnl|CDD|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	5.02392e-143
NZ_CP040250.1|WP_019732674.1|2505294_2506224_-|histone-deacetylase-family-protein	gnl|CDD|212541	cd11599, HDAC_classII_2, Histone deacetylases and histone-like deacetylases, classII. This subfamily includes eukaryotic as well as bacterial Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. In D. discoideum, where four homologs (HdaA, HdaB, HdaC, HdaD) have been identified, HDAC activity is important for regulating the timing of gene expression during development. Also, inhibition of HDAC activity by trichostatin A is shown to cause hyperacetylation of the histone and a delay in cell aggregation and differentiation.	1.70246e-166
NZ_CP040250.1|WP_033718259.1|2517273_2518053_-|ABC-transporter-permease	gnl|CDD|272861	TIGR00025, Mtu_efflux, ABC transporter efflux protein, DrrB family. The seed members for this model are a paralogous family of Mycobacterium tuberculosis. Nearly all proteins scoring above the noise cutoff are from high-GC Gram-positive organisms. The members of this paralogous family of efflux proteins are all found in operons with ATP-binding chain partners. They are related to a putative daunorubicin resistance efflux protein of Streptomyces peucetius. This model represents a branch of a larger superfamily that also includes NodJ, a part of the NodIJ pair of nodulation-triggering signal efflux proteins. The members of this branch may all act in antibiotic resistance.	8.83806e-54
NZ_CP040250.1|WP_137987534.1|2497212_2498460_+|phosphoglycerate-kinase	gnl|CDD|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP040250.1|WP_033720734.1|2500544_2503352_+|phosphoenolpyruvate-carboxylase	gnl|CDD|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_CP040250.1|WP_019732679.1|2514563_2515538_-|quinone-oxidoreductase	gnl|CDD|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	8.61611e-172
NZ_CP040250.1|WP_033710672.1|2499523_2500441_-|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|274651	TIGR03564, F420_MSMEG_4879, F420-dependent oxidoreductase, MSMEG_4879 family. Coenzyme F420 is produced by methanogenic archaea, a number of the Actinomycetes (including Mycobacterium tuberculosis), and rare members of other lineages. The resulting information-rich phylogenetic profile identifies candidate F420-dependent oxidoreductases within the family of luciferase-like enzymes (pfam00296), where the species range for the subfamily encompasses many F420-positive genomes without straying beyond. This family is uncharacterized, and named for member MSMEG_4879 from Mycobacterium smegmatis. [Unknown function, Enzymes of unknown specificity].	1.05566e-123
NZ_CP040250.1|WP_003876059.1|2499272_2499506_+|preprotein-translocase-subunit-SecG	gnl|CDD|235881	PRK06870, secG, preprotein translocase subunit SecG; Reviewed.	6.06782e-13
NZ_CP040250.1|WP_019732673.1|2504306_2505293_+|aldo/keto-reductase	gnl|CDD|381310	cd19084, AKR_AKR11B1-like, AKR11B1/AKR11B2 subfamily of aldo-keto reductase (AKR). Bacillus subtilis YhdN, also called general stress protein 69 (GSP69), is a founding member of aldo-keto reductase family 11 member B1 (AKR11B1). It acts as an aldo-keto reductase (AKR) that catalyzes the reversible reduction of ketones to the respective alcohols using NAD(P)H as a hydride donor. Escherichia coli YdjG is a founding member of aldo-keto reductase family 11 member B2 (AKR11B2). It catalyzes the NADH-dependent reduction of methylglyoxal (2-oxopropanal) in vitro. It may play some role in intestinal colonization.	5.19804e-138
NZ_CP040250.1|WP_033710634.1|2513460_2514387_+|protoheme-IX-farnesyltransferase	gnl|CDD|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	4.31569e-140
NZ_CP040250.1|WP_137987536.1|2518981_2520685_-|hypothetical-protein	gnl|CDD|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	6.04356e-61
NZ_CP040250.1|WP_019732672.1|2503427_2504207_+|DUF4239-domain-containing-protein	gnl|CDD|372881	pfam14023, DUF4239, Protein of unknown function (DUF4239). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 254 and 270 amino acids in length.	9.58462e-10
NZ_CP040250.1|WP_023863986.1|2511104_2513204_-|transketolase	gnl|CDD|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NZ_CP040250.1|WP_019732675.1|2506681_2507437_-|6-phosphogluconolactonase	gnl|CDD|376480	pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.	2.92236e-94
NZ_CP040250.1|WP_003877656.1|2518049_2518958_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.07691e-87
NZ_CP040250.1|WP_023900055.1|2508425_2509970_-|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NZ_CP040250.1|WP_042906634.1|2509966_2511088_-|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NZ_CP040250.1|WP_137987535.1|2516145_2517099_-|heme-A-synthase	gnl|CDD|224528	COG1612, CtaA, Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones].	8.00846e-58

Protein sequences

>NZ_CP040250.1|WP_019732675.1|2506681_2507437_-|6-phosphogluconolactonase
MSTRIEIFPDSQALVTAAAARLADTIADAVAARGRALIVLTGGGNGIGLLKSLAGRPIDWSAVHLFWGDERYVPEDDDERNEKQAREALLSHVDIPSSQVHPMPASDGEFGSDLAAAALAYEQLLAANAPPGQPVPNFDVHLLGMGPEGHINSLFPDTPAVLETTRMVVPVEDSPKPPPQRITLTLPAIARSREVWLMVSGAGKADAVAAAINGAAPVSVPAAGAVGLDTTLWLLDREAAAKLPPGTAVQG
>NZ_CP040250.1|WP_003876065.1|2506242_2506641_-|hypothetical-protein
MTGMADRTVRGGQERSRIKTLTQAALNADKTVEQVEDVLDGLSSTLKELSSSLAALNATVERMETGLDHLDGTLASLDDLAKRLIVLVEPVEAIVARVDDLVKVGETVMSPLSVTEHAVRGLVDRLRNRTAQ
>NZ_CP040250.1|WP_019732674.1|2505294_2506224_-|histone-deacetylase-family-protein
MATLLLHHPDFAAHRTAPGHPERPDRYRAVAAALSLPGFDALVRETAEPAELAATRYVHSNRYVDALEAARPQHGYVYLDGGDTMMEPSTWETALRGVGATLQAVDRVLAGDVQNAFVACRPPGHHAETERAMGFCLFNNISIGARHAQRKHGLMRVAIVDFDVHHGNGTQQIFYSDPSVLYASTHQMPLFPGTGAAAETGVGNIFNSPLAPGDGGAELRAAFTDRIVPALQAFSPELIIVSAGFDAHERDPLGSLTMTTDDFGWVTRELMKSAEKLCDGRLVAVLEGGYDLQALADSVTAHVGELLKG
>NZ_CP040250.1|WP_019732673.1|2504306_2505293_+|aldo/keto-reductase
MKTITFGKTGLEVSRLAFGTWEFCSDWGHADEDAAITMIRSARDLGINFFDTAQQYGFGASERLLGKALRDDLARARDEVVIATKGGLRATDSGLVRDASPQWLRKGVESSLTALGIDHIDVYLVHWPDPRMPAAETAGALAELVSEGKIRHVGVSNYDTAQVEEFSATLPVEVVQPPYHLFRRDIEDTLLPYAREHDIGVMVYGPLAHGLLTGTVKPDTRFAPQDWRAKSDIFSGDGFLRNLEVVAQLQELASDLGVTISQLAIARVLAQPGVHVAIVGAQHLHYLQESARAADVTLSDTDLAAVDNVLAAATPVGGPYPEMHQKAS
>NZ_CP040250.1|WP_019732672.1|2503427_2504207_+|DUF4239-domain-containing-protein
MSGPGLPLWLLLVCAVAAAIGVAVGAIWLGRRLLQGRQQNPAIASFLTVVGFVYGALLGFTVVATWEHFSSTQVVVSAEASALTTMYRQSVAMPEPERTEIQELLRKYAGAVAGPEWNKQRNEGARAAITRMYRTVGRQQPNVAARPINQQFLNQLSELASDRNERIVGTKPRIPPLLWAGLIFGAVVLVAFTGFLRLGSTVGHVVVSGTVAVLLALLLCTVFELDHSYATDQRITSGPFQHALDIFDAVDNDSRYFPR
>NZ_CP040250.1|WP_033720734.1|2500544_2503352_+|phosphoenolpyruvate-carboxylase
MVEASEGTLEPIGAVQRTLVGREATEPMRADIRLLGAILGDTVREQNGQQVFELVERARVESFRVRRSEIDRAELARMFAGIDIHQAIPVIRAFSHFALLANVAEDIHRERRRAIHVAAGEPPQDSSLAATYAKLDRAQLDSATVAEALRGAVVSPVITAHPTETRRRTVFVTQHRITELMRLHAEGHTETDDGRNIELELRRQVLTLWQTALIRLSRLQITDEIEVGLRYYAAAFFKVIPQVNAEVRNALRARWPGADLLDEPIVAPGSWIGGDRDGNPNVTADVVRRATGDAAYTALAHYLAELTACEQELSMSARLVAVTPELAALAEDCAEKARADEPYRRALRVIRGRLTATAAEILDRRPQHELDLGLPPYATPAELRADLDTVDASLRAHGSALLADDRLALLREGVRVFGFHLCGLDMRQNSDVHEEVVAELLAWAGVHPDYRSLPEDERVELLAAELGTRRPLVGDRAELSELADKELGVVRAAAHAIRRYGPAAVPNYVISMCRSVSDVLEAAILLKEAGLIDASGPEPYCPVGISPLFETIEDLHNGAAILHAMLELPLYRALVAARGQSQEVMLGYSDSNKDGGYLASSWAVYRAELALVEVARKTGIRLRLFHGRGGTVGRGGGPSYEAILAQPPGAVNGSLRLTEQGEVIAAKYAEPQVAQRNLESLVAATLESTLLDVEGLGDTAEPAYAVLDEVAVLAQRAYAELVHETPGFVDYFMASTPVSEIGSLNIGSRPTSRKPTESIADLRAIPWVLAWSQSRVMLPGWYGTGSAFEQWIAAGPQSRAERVDILHDLYRRWPFFRSVLSNLAQVLAKSDLGLAAQYAELVDDAALRRRVFGKIADEHRRTIAMHKLITGQDNLLADNPALARSVFNRFPYLEPLNHLQVELLRRYRSGDNDELVQRGILLTMNGLASALRNSG
>NZ_CP040250.1|WP_033710672.1|2499523_2500441_-|LLM-class-F420-dependent-oxidoreductase
MSAGIILMAHPDAANLVDDVIAQARRAHELGVGQVWLAQQQSYDAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQTAQAAAHGNFSLGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHSGAVDFHGSELSAAPSFPVRVPGGTPIPVYVAAMGPKALQVTGELADGTLPYLAGPRTIEEFIVPRITKAAAEAARPAPRIIAAVPVLLSDDVEGARAAAAQQLSFYETIPSYRNVIAREGLSNAVELAAIGPEESVLRQVRRYFDAGATDVVLSPLDRSASVDREALWRLTAAL
>NZ_CP040250.1|WP_003876059.1|2499272_2499506_+|preprotein-translocase-subunit-SecG
MQLALQITLVVTSILVVLLVLLHRAKGGGLSTLFGGGVQSSLSGSTVVEKNLDRLTLFITGIWLVCIIGMALLIKYR
>NZ_CP040250.1|WP_009977607.1|2498456_2499242_+|triose-phosphate-isomerase
MSRKPLIAGNWKMNLNHFEAIALVQKIAFALPDKYYDKVDVTVLPPFTDLRSVQTLVDGDKLRLSYGAQDLSQHDSGAYTGDISGAFLAKLGCTFVVVGHSERRTYHNEDDALVAAKAAAALKHELTPIICIGEHLEVREAGNHVIHCEEQLRGSLAGLSAEQIGKVVIAYEPVWAIGTGRVASASDAQEVCAAIRKELASLASAQIADSVRVLYGGSVNAKNVGELIAQDDIDGGLVGGASLDGEQFATLAAIAAGGPLP
>NZ_CP040250.1|WP_137987534.1|2497212_2498460_+|phosphoglycerate-kinase
MAVHNLKDLLAEGVSGRGVLVRSDLNVPLDSDGEQGRITDPGRITASVPTLSALVEAGAKVVVAAHLGRPKNGPDPALSLAPVAAALGEQLGRHVQLASDVVGTDALARAEGLTDGDVLLLENIRFDARETSKDDAERLALARQLAELVGSTGAFVSDGFGVVHRKQASVYDVATLLPHYAGTLVAEEIAVLEQLTGSTKRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGFSVGKSLLETEMVDTCRRLLDTYVDVLRLPVDIVAADRFAADAAPQTVPADAIPDDLMGLDIGLGSVKRFTALLSNAETIFWNGPMGVFEFPAFAAGTKGLAEAIAAATGKGAFSVVGGGDSAAAVRALGIPESGFSHISTGGGASLEYLEGKALPGIEVLGRPQPTGGAA
>NZ_CP040250.1|WP_023900055.1|2508425_2509970_-|glucose-6-phosphate-dehydrogenase
MSPARTAQQWHNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAIYDLANRGLLPPSFSLVGFARRDWSTQDFGKVVYEAVKEHCRTPFRQENWDRVAEGFRFVPGAFDDDEAFGRLAETLDKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLESAQSLNKAVNAVFPEESVFRIDHYLGKETVRNILALRFANQLFDPIWNSHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFSPLALQAEKIKVLSATHLAHPLDETTSRGQYTAGWQGGEKVVGLLDEEGFAKDSITETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFKRAPHLPFDATMTDELGANAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEESPEAYEQLILDVLLGEPSLFPVNAEVELAWHILDPVLDNWASGGRPEPYEAGTWGPDSAFEMLHRTGREWRRP
>NZ_CP040250.1|WP_042906634.1|2509966_2511088_-|transaldolase
MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKCVVGVTTNPSIFQKAFAEGHAYDSQIAELAARGADVDATIRTVTTDDVRNACDVLTREWENSDGVDGRVSIEVDPRLAGDTDKTIAQAVELWKIVDRPNLFIKIPATQAGLPAITAVLAEGISVNVTLIFSVERYRAVMDAYLAGMEKAREAGHDLSKIHSVASFFVSRVDTEIDKRLEKIGGERALALRGQAGVANARLAYAAYQEVFEGGQRYQALKADGARVQRPLWASTGVKNPDYSDTLYVTELVAPNTVNTMPEKTIDAVADHGVIRGDTVTGTGPDAQRVFDELAAVGVDLPDVFVVLENEGVEKFVDSWTELMEETQKQLGSATK
>NZ_CP040250.1|WP_023863986.1|2511104_2513204_-|transketolase
MTTLEEISALTQPHLPDDWSELDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRVMRHDPSDTHWLGRDRFVLSAGHSSLTLYLQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTKGVEITTGPLGQGLASAVGMAMASRYERGLFDPDAAAGTSPFDHFIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNQISIEDDTNIALCEDTAARYEAYGWHVQRVEGGENVVAIEEAIAAAKAVTDRPSFIELRTIIGYPAPNAMNTGKAHGAALGEEEVAAVKKILGFDPDKTFQVRDEVIAHTRKLVDRGREAHQKWQTDFDAWAQREPERKALLERLTAEKLPDGWDADLPHWEPGSDAIATRKASGAVLNAVAPKLPELWGGSADLAESNLTTINNADSFGPPSISTKEFTASWYGRVLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASLMDIDTIYVWTHDSIGLGEDGPTHQPIEHLAALRAIPKLSVVRPADANETAYAWRTILARGNGSGPVGLVLTRQGLPVLEGTDADGVARGGYILGSDGEEAGQEPDVILIATGSEVQLAVEAQKLLADKDIVARVVSMPCVEWFESQPDDYRDSVLPPSVSARVAVEAGVAQSWHKLVGDTGKIISIEHYGESADYKTLFREFGFTAEAVAAAAEEVVDN
>NZ_CP040250.1|WP_033710634.1|2513460_2514387_+|protoheme-IX-farnesyltransferase
MSVRGRVAPSQTPSRIPGTVLAYLALTKPRVIELLLVTAIPAMLLAQRGTVNPLLIVNTLIGGMLAAGGANALNCVADADIDKVMKRTARRPLARAAVPTRNALVFGLVLTAGSFLWLWWTTNLLSGLLALATIAFYVFIYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQILVYTWLTVLATLALALATGWLYAAVAVVAGVWFLAMAHQLYAGVRAGEPVKPLRLFLQSNNYLAVVFCALAIDSAIGLPTLL
>NZ_CP040250.1|WP_019732679.1|2514563_2515538_-|quinone-oxidoreductase
MHAIEVSETGGPEVLRYVETPTPTAGPGQVLIKAEAIGVNYIDTYFRSGQYPRELPFIIGQELCGTVAAAGDGVDGFNVGDRVVSAAATGGYAEYATAPASLTAHVPDEVAADVAASALLKGLTAHYLLKSVYPVQAGDTVLVHAGAGGVGLILTQWAHLLGARVITTVSTPEKARRSAQAGADEVLSYPDDADEFGSRIRALTEGAGVAAVYDGVGASTFDASLASLAVRGTLALFGAASGPVPPFDPQRLNAAGSVFLTRPSLAHFIRTGQEFSWRAEELFAAIAAGDITVEVGGRYPLADAARAHRDLQGRKTTGSIVLLP
>NZ_CP040250.1|WP_033710637.1|2515557_2516196_+|hypothetical-protein
MKLARPDVFHPRIVLAGRRDDPGLVSALRRRGLHARRLPWEDPETLHADLVIVRAGPDAARRDEFLAWTGRPRHVLNPPAALAWNLDAHYLRDLRDGGVPTRPGAQPETSLIFLGGAQSHAWPAEPEFESWDLGHAALAVAADHTGIGVPEVLFARADLAGDRLVRLDLVAPELGWRHLDTPGREAAQRRFALAVESACERLGLGPLSHRRP
>NZ_CP040250.1|WP_137987535.1|2516145_2517099_-|heme-A-synthase
MLGRTLLRLVDLLPNPSVGVQRLIAVAVILTQGGIAITGAIVRVTASGLGCPTWPQCFPGSFVPVPHAEVPRIHQAVEFGNRMITLAVVVAAALAVLAVTRARRRPEVLVYAWLMPVSTVVQAVIGGITVRTGLLWWTVAIHLLTSMTMVWLSVLLYVKIGEPDDGVDQPRVPTPLRVLTALSGVNLAAVLVTGTLVTAAGPHAGDRSPTRTVPRLEVQVDTLVHLHSSLLVAYLALIVGLGFGLLAVRAARPILLRLGVLLVLLCAQAAVGTAQYYTGVPAALVAVHVAGAAACTAATAALWASMRQRAQAEPLTG
>NZ_CP040250.1|WP_033718259.1|2517273_2518053_-|ABC-transporter-permease
MTDSGVFPAGTFTPNPRPSAVPKMIAAQYGLELKLLLRNGEQLLLTMFIPITLLVGLTLLPLGSFGQHRAATFTPVIMALAVISTAFTGQAIAVAFDRRYGALKRLGATPLPVWGIIAGKSLAVVTVVFLQAILLGAIGFALGWRPALAALALGAAVIALGTAVFAALGLLLGGTLRAEIVLALANLMWFVFAGLGALTVDSGVIPAGVKWAARLTPSGALTEALSRAMTLSADWFGMAVLVAWGALGALGALRWFRFT
>NZ_CP040250.1|WP_003877656.1|2518049_2518958_-|ABC-transporter-ATP-binding-protein
MRLRGVSKHYGSTTAVRDLDLEVHAAEVLALLGPNGAGKTTTVEMCEGFVRPDAGTLEVLGLDPIADNARLRPRIGVMLQGGGGYPAARAGEMLNLVAAYAADPLDPAWLLDTLGLTDAARTTYRRLSGGQQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVVLTTHQLKEAEELADRLVIIDHGATVAAGTPAELMRSGAKDQLRFSAPPRLDLSLLSAALPEDYKATELTPGEYLVEGPVDPQVLATVTAWCARIDVLATDMRVEQRSLEDVFLDLTGRKLRQ
>NZ_CP040250.1|WP_137987536.1|2518981_2520685_-|hypothetical-protein
MAARHHTLSSSIASLHGDEQAVGSPLNDTELTALRRTRLFGASGTMLMAIGALGAGARPVVQDPTFGVRLLNLPSRIQTVSLTMTTTGAVMMALAWLMLGRFALGTRRMSRGDLDRTLLLWVLPLLIAPPMYSKDVYSYLAQSQISLEGLDPYRVGPASGLGLSHIFTLSVPTLWRETPAPYGPLFLWIGRGISAITGENIVAAVLCHRLVELIGVGLIVWATPRLARRCGVAEVSALWLGAANPLLIMHLVAGVHNEALMLGLMLAGAEFALRGIDSARLLPHSLRPGPDWEPLGMLLAGAVLITLSSQVKLPSLLALGFVTMALAYRCGGNLRAVLLAGGGMAALSLAVMALVGWASGLGFGWIYTLGTANVVRSWMSPPTLLALGTGQVGILLGLGDHTTAVLGLTRAIGVLIITVMVGWLLLAVFRGRLHPIGGLGVALGVTVLLFPVVQPWYLLWAIIPLAAWATRTGFRVAAIVISLVVGIFGPTANGDRFALFQIVDATLASTVIVAVLIALTYTRLPWRPLPAPQRAPHGQPVIDPVAPARSSSTPRPAPAHDAYADST

Crispr_ID: NZ_CP040250_5

• CRISPR_ID: NZ_CP040250_5
• CRISPR_location: 3317614-3317712
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040250_5

Consensus_repeat	Method
CCGCTCGGGGTCGGGCCGCAACCG	CRISPRCasFinder

spacers of NZ_CP040250_5

>5.1|3317638|51|NZ_CP040250|CRISPRCasFinder
TTGGCCTGCGACCCGGGCCAATGGTGGGACCCGACGGCCAACGTGTGCCGG

CRISPR arrays and Neighbor proteins around NZ_CP040250_5

CRISPR arrays

The CRISPR arrays of NZ_CP040250_5

>merge|NZ_CP040250|5|3317614-3317712|CRISPRCasFinder
CCGCTCGGGGTCGGGCCGCAACCGTTGGCCTGCGACCCGGGCCAATGGTGGGACCCGACGGCCAACGTGTGCCGGCCGCTGGGGGTCGGGCCGCAACCG

>NZ_CP040250|5|5|3317614-3317712|CRISPRCasFinder
CCGCTCGGGGTCGGGCCGCAACCG	TTGGCCTGCGACCCGGGCCAATGGTGGGACCCGACGGCCAACGTGTGCCGG
CCGCTGGGGGTCGGGCCGCAACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040250.1|WP_011724997.1|3309297_3310527_+|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960
NZ_CP040250.1|WP_011725000.1|3305625_3307032_+|acyltransferase	unknown	unknown	gnl|CDD|334202
NZ_CP040250.1|WP_033722653.1|3308689_3309133_-|Hsp20-family-protein	unknown	unknown	gnl|CDD|365807
NZ_CP040250.1|WP_062895398.1|3311221_3311800_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040250.1|WP_011725002.1|3304418_3304976_-|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223619
NZ_CP040250.1|WP_062887756.1|3322919_3324740_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|223953
NZ_CP040250.1|WP_137987588.1|3308249_3308630_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|133394
NZ_CP040250.1|WP_011724991.1|3319803_3320646_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378964
NZ_CP040250.1|WP_062887792.1|3315342_3316818_-|biotin-carboxylase	unknown	unknown	gnl|CDD|180605
NZ_CP040250.1|WP_033711481.1|3319448_3319850_-|glyoxalase	unknown	unknown	gnl|CDD|319943
NZ_CP040250.1|WP_009976824.1|3307717_3308137_-|Hsp20-family-protein	unknown	unknown	gnl|CDD|365807
NZ_CP040250.1|WP_011724993.1|3318986_3319298_-|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NZ_CP040250.1|WP_009976825.1|3307084_3307405_-|J-domain-containing-protein	unknown	unknown	gnl|CDD|365959
NZ_CP040250.1|WP_003876695.1|3322242_3322896_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|188314
NZ_CP040250.1|WP_023861579.1|3320869_3321307_+|hypothetical-protein	unknown	unknown	gnl|CDD|366161
NZ_CP040250.1|WP_019732280.1|3326490_3327309_+|CoA-transferase	unknown	unknown	gnl|CDD|224717
NZ_CP040250.1|WP_132160223.1|3317786_3318872_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NZ_CP040250.1|WP_062887574.1|3310878_3311217_-|DUF3024-domain-containing-protein	unknown	unknown	gnl|CDD|371425
NZ_CP040250.1|WP_011724988.1|3325789_3326383_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP040250.1|WP_062887757.1|3324884_3325769_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|131480

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040250.1|WP_011724997.1|3309297_3310527_+|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	1.4884e-178
NZ_CP040250.1|WP_011725000.1|3305625_3307032_+|acyltransferase	gnl|CDD|334202	pfam00668, Condensation, Condensation domain. This domain is found in many multi-domain enzymes which synthesize peptide antibiotics. This domain catalyzes a condensation reaction to form peptide bonds in non- ribosomal peptide biosynthesis. It is usually found to the carboxy side of a phosphopantetheine binding domain (pfam00550). It has been shown that mutations in the HHXXXDG motif abolish activity suggesting this is part of the active site.	3.46822e-19
NZ_CP040250.1|WP_033722653.1|3308689_3309133_-|Hsp20-family-protein	gnl|CDD|365807	pfam00011, HSP20, Hsp20/alpha crystallin family. Not only do small heat-shock-proteins occur in eukaryotes and prokaryotes but they have also now been shown to occur in cyanobacterial phages as well as their bacterial hosts.	2.33587e-28
NZ_CP040250.1|WP_011724991.1|3319803_3320646_-|AraC-family-transcriptional-regulator	gnl|CDD|378964	pfam12833, HTH_18, Helix-turn-helix domain.	2.55315e-14
NZ_CP040250.1|WP_011725002.1|3304418_3304976_-|peptidylprolyl-isomerase	gnl|CDD|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	5.25617e-23
NZ_CP040250.1|WP_062887756.1|3322919_3324740_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|223953	COG1022, FAA1, Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism].	0
NZ_CP040250.1|WP_137987588.1|3308249_3308630_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	3.03029e-36
NZ_CP040250.1|WP_062887792.1|3315342_3316818_-|biotin-carboxylase	gnl|CDD|180605	PRK06524, PRK06524, biotin carboxylase-like protein; Validated.	0
NZ_CP040250.1|WP_033711481.1|3319448_3319850_-|glyoxalase	gnl|CDD|319943	cd08355, TioX_like, Micromonospora sp. TioX and similar proteins. Micromonospora sp. TioX is encoded by a gene of the thiocoraline biosynthetic gene cluster. Thiocoraline is a thiodepsipeptide with potent antitumor activity. TioX may be involved in thiocoraline resistance or secretion. TioX belongs to vicinal oxygen chelate (VOC) superfamily that is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.26108e-32
NZ_CP040250.1|WP_009976824.1|3307717_3308137_-|Hsp20-family-protein	gnl|CDD|365807	pfam00011, HSP20, Hsp20/alpha crystallin family. Not only do small heat-shock-proteins occur in eukaryotes and prokaryotes but they have also now been shown to occur in cyanobacterial phages as well as their bacterial hosts.	1.2009e-29
NZ_CP040250.1|WP_011724993.1|3318986_3319298_-|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	7.22654e-12
NZ_CP040250.1|WP_009976825.1|3307084_3307405_-|J-domain-containing-protein	gnl|CDD|365959	pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.	1.61446e-18
NZ_CP040250.1|WP_003876695.1|3322242_3322896_+|HD-domain-containing-protein	gnl|CDD|188314	TIGR03401, Uncharacterized_protein_YFL061W/YNL335W, HD domain protein, cyanamide hydratase family. Members of this protein family are known, so far, in the Ascomycota, a branch of the Fungi, and contain an HD domain (pfam01966), found typically in various metal-dependent phosphohydrolases. The only characterized member of this family, from the soil fungus Myrothecium verrucaria, is cyanamide hydratase (EC 4.2.1.69), a zinc-containing homohexamer that adds water to the fertilizer cyanamide (NCNH2), a nitrile compound, to produce urea (NH2-CO-NH2). Homologs are likely to be nitrile hydratases.	4.97586e-13
NZ_CP040250.1|WP_023861579.1|3320869_3321307_+|hypothetical-protein	gnl|CDD|366161	pfam00553, CBM_2, Cellulose binding domain. Two tryptophan residues are involved in cellulose binding. Cellulose binding domain found in bacteria.	2.98001e-36
NZ_CP040250.1|WP_019732280.1|3326490_3327309_+|CoA-transferase	gnl|CDD|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	1.46156e-44
NZ_CP040250.1|WP_132160223.1|3317786_3318872_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.04144e-15
NZ_CP040250.1|WP_062887574.1|3310878_3311217_-|DUF3024-domain-containing-protein	gnl|CDD|371425	pfam11225, DUF3024, Protein of unknown function (DUF3024). This family of proteins has no known function.	1.23698e-17
NZ_CP040250.1|WP_011724988.1|3325789_3326383_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.04646e-08
NZ_CP040250.1|WP_062887757.1|3324884_3325769_+|alpha/beta-fold-hydrolase	gnl|CDD|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	5.62765e-31

Protein sequences

>NZ_CP040250.1|WP_062887792.1|3315342_3316818_-|biotin-carboxylase
MTHAGEPQPRRALNGLSDIRAFFHTNSVPLYFISPTPFNLLGIDRWIRNFFYLTYFDSFEGIHSRVFVPRRRDRIDFDSMGDVCNHLLRDPETLEFIAGRGPGGKACFVMMDEETQALARQAGLQVMHPPVELRNRLGSKTVMTRLADEAGIPSVPHVMGRAGSYQELLTLAQDAGLGDDLVISIPYGAAGSGTFFVRGQRDWDEHAGDLTAQQEFKVMKRIRNVEVCLEGAVTRHGTVIGPAMTSLVGYPELTPHRGAWCGNDIWREVLPPGQTHAARQMVGKLGDILSREGYRGYFEVDLLHDLDSDELYLGEVNPRLSGASPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIEGINARWERGYGEDEVWGQVILAETSPDVELFTATPRTGVWRIDDDGRVSFSRTANDWATLLDGSEAFYMRVAAPGDLRSEGAQLGVLVTRGHLQTDDYRLTERCQRWVKGMKAKFASTPLAPATPIVSRLVARA
>NZ_CP040250.1|WP_062895398.1|3311221_3311800_-|hypothetical-protein
MLVADLQHFLDVGPETPGPARALAEHLGGIVSAASAGDAHTRWETALPCRRRPANRRCPGRITVVRGDAEQPIGWQCSHCGDDGTISNWAASIYDLRRQQLTAAQPRRDIPIDADTAATLRTLPFLDNNCQRAVFAICAHGGELHLTMTAAELDDLIDALAAESNHEPHRRRQRQLDTAYDTLTAATDTPRW
>NZ_CP040250.1|WP_062887574.1|3310878_3311217_-|DUF3024-domain-containing-protein
MALPELDIARVQQWCAARVPEHARHQVRVECDVAARHLTIVERRAPWREDYGPDWTSFPIARLRYTATTNTWTLYWRDRHLKFHRYDTIDPTPHIHDVLTEIDHNPSGIFWG
>NZ_CP040250.1|WP_011724997.1|3309297_3310527_+|tRNA-4-thiouridine(8)-synthase-ThiI
MHMQCCVLLKYGEMVLKGGNRRWFEQWLLTNLDDALSAWPPEHRPAVRRRGGVLVLFTSPELQDELVALARNLIGISLVQPVWRVPRSARAAETAAVELLRDHCTQDGAPTFAVRCHRRDKRFGLSSEQLAARIGARVRADLGWPVDLSHPELELTVEVDRREIFLGTRTHPGQGGLPVGSSGRAVVLLSGGFDSPVAAYRAMRRGLACDFLHCTGAPFTDASSTYKAYALVRQLTRFQPRSRLYVAAVGRAQRTLAASGAGEAQIVAQRRLYLRLACGLAERIGAQAVVTGDSLGQVASQTLPNLAATEQAATLPVLRPLLGFDKQEILAEARRIGTAEIAMLPDQDCCQLFLPRRVATHAAVDQLLPVEARAGVDTLVGNLLDRMQRFDFGPEAADVESAATASRVG
>NZ_CP040250.1|WP_033722653.1|3308689_3309133_-|Hsp20-family-protein
MVNMLRFDPFFRDIDRLTQQLWGAVPWGTAAQPALVPMDAWRDGEKLVVEFDLPGVLPESLDVNVEHDVLTVRAERPAIDEDRNGVVSERPRGVFSRQVYLGHGLDTDNIHADYVDGVLRLTIPVAEAAKPRKIEVAAGKHQRAINA
>NZ_CP040250.1|WP_137987588.1|3308249_3308630_+|helix-turn-helix-transcriptional-regulator
MRGDPTPRSARGVYGISVASELSGIPPQTLRHYERRGLLTPARSDGGTRRYSDDDLARLKRISQLVDQGVNLVGVARILDLESKNDQLKADYSALELLNAQLKTRQKSERAAAPRQGRGEARREAV
>NZ_CP040250.1|WP_009976824.1|3307717_3308137_-|Hsp20-family-protein
MVLMRTDPFRDLDRWTQQVLGTAARPAVMPMDAWRDGDQFVVEFDLPGVNADSLDLDVERNVLTVRAERPDLDQNREMVSAERPRGVFSRQLFLGDNLDTDKIEANYHDGVLRLTIPVAEKAKPRRIEINHNHRTAINA
>NZ_CP040250.1|WP_009976825.1|3307084_3307405_-|J-domain-containing-protein
MTNPYLVLGVSPTATQAEITRAYRRHLRAHHPDTSPPDSATESSERLSEILAAYALLRDPARRADYDREHRVHQRIRPAVTRVTRIEPADEQPPLRAGPVRWHRRY
>NZ_CP040250.1|WP_011725000.1|3305625_3307032_+|acyltransferase
MPASYQQLHHLRRFSEHAARGLDMARLNIGVWDISGVCDVAAMTEAINAHLRRHDTYHSWFEHRTDGRIVRHTFDDPADIEFAALQRGEMTPTELRAHILATPNPLRWDCFTFGLVQHPDHFTFYMSADHLVIDGMSVGVIFLEIHLTYAALVSGGRPLPLPEPASYHDYCRRQHQHTEALTLQSPQVRAWIRFAEDNGGTLPSFPLPLGDPSVPCGSGVVVAPLMDESQTERFDATCTKAGARFSGGVFACAAFAEYELTGAETYCAITPYDHRSTPAEFVTPGWFASFIPVTFPVAGASFGDAVIAAQASFDSAIGLADVPFDRVLELSSFGGRISKPTGDVHMLSFADARGIPFSGQWDGLNAGIYGDGRSSDQVLMWVNRFDTETTLTVAFPQNPVARDSVERYIRAVRAMCLRVVEHGAAAVPNRRRVVAAVNASAARSTANAADRTDRRLQGAGFGANPVLR
>NZ_CP040250.1|WP_011725002.1|3304418_3304976_-|peptidylprolyl-isomerase
MNSVRTFSVAAFAACFTAAAAMLASAGTAGAADSCPTAAPPSGGTPDWTLTGTTGSVAVTGSTDTAAPVVNVTAPFSVTQTQVHTLRAADGPAVPGTARVSVCYMGVNGRDGTVFDSSYQRGAPVDFPLGGVVPGFQKAIAGQKVGSTVAVAMTSADGYPDGQPSAGIRPGDTLVFAIKILGATT
>NZ_CP040250.1|WP_132160223.1|3317786_3318872_-|IS630-family-transposase
MPSPIAVPVVLTDDEREQLQGWARRPKSAQALALRSRIVLACEGDSSNTAIARDLGITRGMVTKWRNRFAADRIEGLLDEPRPGRPRVVGDERIEALITATLETTPPDATHWSTRSMAEHLGLSQSMVSRVWRAFGLAPHKQDSWKLSKDPLFVQKVRDVVGLYLNPPERAVVLCVDEKTQIQALNRTAPVFPMLPGTPARASHDYVRHGTSSLYAALDLATGQVIGALHSRHRAQEFLAFLKKIDAHVPADLDCHVVLDNASTHKTPQVKRWLTAHPRFVLHFTPTSSSWLNLVERWFAELTTKKLRRGTHTSVRQLNTDIRTWIQTWNDNPRPYVWTKTADQILESIANYCKRINDSQH
>NZ_CP040250.1|WP_011724993.1|3318986_3319298_-|DUF732-domain-containing-protein
MIGAVLVGGAGIAAATPQDDAYLAQLRAAGLTWPPKTEEALIAEAHDVCYDLTWGWTPQQIADDLHARLDNKGVTLLDVGSLVNAAHNIYCPGNVCDAPSLCT
>NZ_CP040250.1|WP_033711481.1|3319448_3319850_-|glyoxalase
MTASNPTVWLTLQAHNAPKLIDYYVETFGFVLAARYGDGETVDHAQLNWPEGSGGIMLGSHKPGAEWCREPGTAGGYVVTADPDALYRRVRQHNAEIVRPLAETDYGAREFTVRDPEGNLWSFGDYGGANPPN
>NZ_CP040250.1|WP_011724991.1|3319803_3320646_-|AraC-family-transcriptional-regulator
MVGYRTLDVPEGVHRGMPSSMLTFIVSLDDGVEAADTATALPAARPTPLILGGLHLRASHVRQRRGQAGVQLAVHPLASRALFGLPSAELPVAEYDATAVLGRDIVDLHHRVAEAHRWPDVFALVAQYLIDARRRRDGATVRPEVLHAWHLLQRSRGLMPVTALADAVGVTTRHLATLFRREVGHSPKTVAMLMRFQHATGRIAESARRHGRVDLARVAADTGYSDQAHLSREFVRFAGVPPQRWLAEEFRNIQDGGHLLGSQWEHDCFESDRLVDTASP
>NZ_CP040250.1|WP_023861579.1|3320869_3321307_+|hypothetical-protein
MAGLDNHVKRCRTALHGAVSAVIVAVVAVLGLAIAPVADAAAPMATLTVEHTWQTGFIARFAITNSSTVPLSDWKLEFDMPAGQSVLHTWNSTLTQSGTHYVLTPANWNRVIAPGGSATGGFRGVLTGTYSPPTNCVLNGQYRCT
>NZ_CP040250.1|WP_003876695.1|3322242_3322896_+|HD-domain-containing-protein
MTTTSSIETIADIAIPDTALVREITEFIRDAEDDLLFHHSRRVFLFGALQGRRRGLQPDLELLYAGAMFHDLGLTERYRDSALRFEVDGANAAREFLLHRGVSKADADKVWLGIALHTTPGVPEFLDPEIALVTAGVETDVVGVGRDDLAPEALAAVIAAHPRPDFKTRILQAFNDGMKHRPHSTFGTMNADVLEHFDPTFARDNLVDLILNNGWPE
>NZ_CP040250.1|WP_062887756.1|3322919_3324740_-|long-chain-fatty-acid--CoA-ligase
MTHAPASRPTTLCEAFQATAAKHPDAVALRTLGDATTITWRQYRDRVRAIAAGLAGLGVGNGDTVALMMSNRPEFHLCDTAVLHTGATPFSVYNTNPPELLAYQFDNADNHVVICEGTFLPQVLAAAQQGGTVEHVVCVDGAANGAIGLDQLEASPAAGFDFERSWRAVGPDDVLTIVYTSGTTGPPKGVELTHTNFIENARITEEVGGITHADRAVSYLPDAHAANRWITHYQNLLYGLQITTVGDFKAVLPALTEVRPTLFLGVPRVWIKAKAGLEAAVDAEPAGKRALAKWAFGVGRARARAVSDGRPVGLAEKLRYAFADRLVLSKVRRRLGMDRLRIGVTGAAPIPREVHEFVLGLGIPVCEGYGMTECTAGATVNRPERIKIGTVGTPVPGTEVTVASDGEVLVRGKNVMRGYRKAPEKTAEAIDSDGWLHTGDIGEIDEDGYLRIVDRKKELIINAAGKNMSPTNIENTIAASCPLAGPVVVIGDARAYNTALITLDPDSITEYAHAHGLSGSLRELVRNPAVRAEIEKGMAAANRRLSRVEQIKRYTVLADVWEPGSQYLTPTAKLKRKPIATGYAAQIDAMYTEQGKRSAGHSAASD
>NZ_CP040250.1|WP_062887757.1|3324884_3325769_+|alpha/beta-fold-hydrolase
MFREPRIAYAATTVATHDGAQLHVRSYGSAFGQPIVLIHGFGCRIEYWNPQINALAAKYRVIAYDQRGLGRSTLGSDGVRPDVLGRDLAAVLNAVLAPGERAVLVGHSFGGITIMAWAQRFAAHAVSAVLLANTIAERFSATTMLLPFADRYRHIRRPLITALAGSTMTLPSIRWSRWPLQRMALSRYADRQAVDFIYEILADCRTDVRAVWGAGLSGLDVTAGLEKLTVPTTVVTGTEDRLTPPAVAHRIAETLQVRGSLHRFARFPRAGHCTNIEVPYAFNAEIEQLADATR
>NZ_CP040250.1|WP_011724988.1|3325789_3326383_-|TetR/AcrR-family-transcriptional-regulator
MVMTNPRATNEDLTAKARIRNAALDLYAQYGEDRISLRDIASAAGVTLGLVQHHFKTKAGVRDAVDQLVVDYFAHALAQVPAEGSARHVAAARDEAVARMLRDNPPVVNYVRRAVLDPSEDRLHLLDALIELTRREITALRGSGVASTKRPESTQILGVLIRQMGELLLQPMVDAVWDRVAKPTDARKPRLRITVEN
>NZ_CP040250.1|WP_019732280.1|3326490_3327309_+|CoA-transferase
MQPLIGVTVVSLAVNLPGPLAAARLAELGAAVTKVEPATGDPLAAAAPDWYARLIEHQNVLTLDLKDTGDRAKLDELLAGADLLITSMRPSALHRSGLARPQQKFPRLSLIEIVGHHGEHAETPGHDLNYQAAQGTLTPPHMPKVPIADVLGAERAVSSALAALLQAAKAGAGQRYRVVLEEAAARAGDAVRYGLMGEGAVLGGAYPGYGIYASADGYVALGAIEPHFFARTCQVFGADGSHESLGAAFAAKTTAELEDLARHMDIPLNEVR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040250_4	4.1|2508368|25|NZ_CP040250|CRISPRCasFinder	2508368-2508392	25	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	34490-34514	4	0.84
NZ_CP040250_4	4.1|2508368|25|NZ_CP040250|CRISPRCasFinder	2508368-2508392	25	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	481677-481701	4	0.84
NZ_CP040250_4	4.1|2508368|25|NZ_CP040250|CRISPRCasFinder	2508368-2508392	25	NC_031122	Gordonia phage Eyre, complete genome	22215-22239	4	0.84
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NZ_CP030128	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence	279167-279198	6	0.812
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MF141540	Mycobacterium phage Avocado, complete genome	31893-31924	8	0.75
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MK016494	Mycobacterium phage Filuzino, complete genome	35298-35329	8	0.75
NZ_CP040250_3	3.4|2179310|35|NZ_CP040250|CRISPRCasFinder	2179310-2179344	35	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	620134-620168	8	0.771
NZ_CP040250_3	3.4|2179310|35|NZ_CP040250|CRISPRCasFinder	2179310-2179344	35	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1192931-1192965	8	0.771
NZ_CP040250_3	3.4|2179310|35|NZ_CP040250|CRISPRCasFinder	2179310-2179344	35	MN694530	Marine virus AFVG_250M438, complete genome	7767-7801	8	0.771
NZ_CP040250_3	3.4|2179310|35|NZ_CP040250|CRISPRCasFinder	2179310-2179344	35	MN694240	Marine virus AFVG_250M436, complete genome	8280-8314	8	0.771
NZ_CP040250_3	3.4|2179310|35|NZ_CP040250|CRISPRCasFinder	2179310-2179344	35	MN694170	Marine virus AFVG_250M437, complete genome	30879-30913	8	0.771
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	619056-619087	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1050461-1050492	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	686591-686622	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	236107-236138	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1603189-1603220	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	619056-619087	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MN369749	Mycobacterium phage MinionDave, complete genome	36157-36188	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MT684597	Mycobacterium phage Mandlovu, complete genome	34776-34807	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MN585973	Mycobacterium phage StAnnes, complete genome	36599-36630	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MT684593	Mycobacterium phage Moonbeam, complete genome	35674-35705	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MN586005	Mycobacterium phage Lorde, complete genome	34870-34901	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NC_048729	Mycobacterium phage Renaud18, complete genome	36966-36997	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MH077580	Mycobacterium phage Melissauren88, complete genome	35620-35651	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MT684595	Mycobacterium phage Mova, complete genome	35440-35471	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NC_011288	Mycobacterium phage Fruitloop, complete genome	37164-37195	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MN369752	Mycobacterium phage Flathead, complete genome	36671-36702	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	KR824843	Mycobacterium phage Ovechkin, complete genome	36001-36032	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MK494118	Mycobacterium phage Cornucopia, complete genome	37451-37482	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MF668270	Mycobacterium phage Emma, complete genome	35718-35749	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	KF114874	Mycobacterium phage Bobi, complete genome	36949-36980	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	KM652553	Mycobacterium phage CaptainTrips, complete genome	35382-35413	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	JN699012	Mycobacterium phage SG4, complete genome	35380-35411	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MN586004	Mycobacterium phage Strokeseat, complete genome	34833-34864	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MN585987	Mycobacterium phage Enby, complete genome	34895-34926	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	MT684601	Mycobacterium phage Hlubikazi, complete genome	34834-34865	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	KT281795	Mycobacterium phage XFactor, complete genome	35328-35359	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NC_025433	Mycobacteriophage Taj, complete genome	36887-36918	9	0.719
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	323951-323982	10	0.688
NZ_CP040250_1	1.1|626089|32|NZ_CP040250|CRISPRCasFinder	626089-626120	32	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	719994-720025	10	0.688

1. spacer 4.1|2508368|25|NZ_CP040250|CRISPRCasFinder matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

tgcgctctgcatcgtcgtggcgcgt	CRISPR spacer
gacgctcttcatcgtcgtggcgcgg	Protospacer
 .****** *************** 

2. spacer 4.1|2508368|25|NZ_CP040250|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.84

tgcgctctgcatcgtcgtggcgcgt	CRISPR spacer
cgcgctcttcttcgtcgtggcgcgc	Protospacer
.******* * *************.

3. spacer 4.1|2508368|25|NZ_CP040250|CRISPRCasFinder matches to NC_031122 (Gordonia phage Eyre, complete genome) position: , mismatch: 4, identity: 0.84

tgcgctctgcatcgtcgtggcgcgt	CRISPR spacer
ggcgctctgcatcgtcgtcgcgggc	Protospacer
 ***************** *** *.

4. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NZ_CP030128 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

gacgccagagcccgacggtcacgctggc-gtga	CRISPR spacer
gcacccagagccagacggtgacgctggctgtg-	Protospacer
*   ******** ****** ******** *** 

5. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MF141540 (Mycobacterium phage Avocado, complete genome) position: , mismatch: 8, identity: 0.75

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agcgccagagcacgacggacacgctgtggtcg	Protospacer
..********* ****** *******  ** .

6. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MK016494 (Mycobacterium phage Filuzino, complete genome) position: , mismatch: 8, identity: 0.75

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aattccctagcccgacggtcacgccgccgtgt	Protospacer
.*. **  ****************.* **** 

7. spacer 3.4|2179310|35|NZ_CP040250|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.771

gggtggcggcgggtgccggagccgacggcgcagcg	CRISPR spacer
agggcgcggcgggtgccggatccgacggggccgac	Protospacer
.**  *************** ******* ** *  

8. spacer 3.4|2179310|35|NZ_CP040250|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.771

gggtggcggcgggtgccggagccgacggcgcagcg	CRISPR spacer
agggcgcggcgggtgccggatccgacggggccgac	Protospacer
.**  *************** ******* ** *  

9. spacer 3.4|2179310|35|NZ_CP040250|CRISPRCasFinder matches to MN694530 (Marine virus AFVG_250M438, complete genome) position: , mismatch: 8, identity: 0.771

gggtggcggcgggtgccggagccga-cggcgcagcg	CRISPR spacer
tggtggcggcgggcggcggagccgacccgctcgac-	Protospacer
 ************.* ********* * ** *..* 

10. spacer 3.4|2179310|35|NZ_CP040250|CRISPRCasFinder matches to MN694240 (Marine virus AFVG_250M436, complete genome) position: , mismatch: 8, identity: 0.771

gggtggcggcgggtgccggagccga-cggcgcagcg	CRISPR spacer
tggtggcggcgggcggcggagccgacccgctcgac-	Protospacer
 ************.* ********* * ** *..* 

11. spacer 3.4|2179310|35|NZ_CP040250|CRISPRCasFinder matches to MN694170 (Marine virus AFVG_250M437, complete genome) position: , mismatch: 8, identity: 0.771

gggtggcggcgggtgccggagccga-cggcgcagcg	CRISPR spacer
tggtggcggcgggcggcggagccgacccgctcgac-	Protospacer
 ************.* ********* * ** *..* 

12. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aataccagagcccgacggccgcgctggctacc	Protospacer
.*..**************.*.*******    

13. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aataccagagcccgacggccgcgctggctacc	Protospacer
.*..**************.*.*******    

14. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aataccagagcccgacggccgcgctggctacc	Protospacer
.*..**************.*.*******    

15. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aataccagagcccgacggccgcgctggctacc	Protospacer
.*..**************.*.*******    

16. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aataccagagcccgacggccgcgctggctacc	Protospacer
.*..**************.*.*******    

17. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
aataccagagcccgacggccgcgctggctacc	Protospacer
.*..**************.*.*******    

18. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MN369749 (Mycobacterium phage MinionDave, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

19. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MT684597 (Mycobacterium phage Mandlovu, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

20. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MN585973 (Mycobacterium phage StAnnes, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

21. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MT684593 (Mycobacterium phage Moonbeam, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

22. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MN586005 (Mycobacterium phage Lorde, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

23. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NC_048729 (Mycobacterium phage Renaud18, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
cgttccctagcccgacggtcacgccgccgtgt	Protospacer
 .. **  ****************.* **** 

24. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MH077580 (Mycobacterium phage Melissauren88, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

25. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MT684595 (Mycobacterium phage Mova, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

26. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NC_011288 (Mycobacterium phage Fruitloop, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

27. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MN369752 (Mycobacterium phage Flathead, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
cgttccctagcccgacggtcacgccgccgtgt	Protospacer
 .. **  ****************.* **** 

28. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to KR824843 (Mycobacterium phage Ovechkin, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
cgttccctagcccgacggtcacgccgccgtgt	Protospacer
 .. **  ****************.* **** 

29. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MK494118 (Mycobacterium phage Cornucopia, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

30. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MF668270 (Mycobacterium phage Emma, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

31. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to KF114874 (Mycobacterium phage Bobi, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

32. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to KM652553 (Mycobacterium phage CaptainTrips, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

33. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to JN699012 (Mycobacterium phage SG4, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

34. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MN586004 (Mycobacterium phage Strokeseat, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

35. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MN585987 (Mycobacterium phage Enby, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

36. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to MT684601 (Mycobacterium phage Hlubikazi, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

37. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to KT281795 (Mycobacterium phage XFactor, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
agttccctagcccgacggtcacgccgccgtgt	Protospacer
... **  ****************.* **** 

38. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NC_025433 (Mycobacteriophage Taj, complete genome) position: , mismatch: 9, identity: 0.719

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
cgttccctagcccgacggtcacgccgccgtgt	Protospacer
 .. **  ****************.* **** 

39. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 10, identity: 0.688

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
cgctggagaacccgacgggcacgctggcgccg	Protospacer
 .*   ***.******** **********. .

40. spacer 1.1|626089|32|NZ_CP040250|CRISPRCasFinder matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 10, identity: 0.688

gacgccagagcccgacggtcacgctggcgtga	CRISPR spacer
cgctggagaacccgacgggcacgctggcgccg	Protospacer
 .*   ***.******** **********. .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1610556 : 1690873	57	Enterobacteria_phage(20.0%)	transposase,tRNA,integrase	attL 1637399:1637458|attR 1702152:1702266
DBSCAN-SWA_2	1693950 : 1731208	22	Mycobacterium_phage(55.56%)	transposase,integrase	attL 1696239:1696256|attR 1708399:1708416

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP040250|1610556:1690873|DBSCAN-SWA
CTCAGCCGCCGGAGTGCATGACGTCGGCGCCGGCCGGCACCGTGCAGTCGTCCGGGTCGTCGAGCCAGCCCTCCGGCAGCACCACCCGCGCGGGTGAACCCTGCCGCCCCCGGGGCCCGGTCGCCTCGTCCGGGAACGGCACCGAGCCGTCCAACCGGTCGAGCAGGCGGTCCAGCTCGTCGAGCGTCGTGACCATCGCCAGCGCGCGCCGCAGCTCGGAACCGGCCGGGAAGCCGTGCAGGTACCAGGCGATGTGCTTGCGGATGTCGCGCATGCCCTTGTCCTCGCCGAAGTGGGCGGCCAGCAGCCGCCCGTGCCGGCGCACGATGTCGGCCACCTGCCCCAGGGTGGGCGGCGTGGGCGGCGGGCTGCCGGTGAACGCGGCCGACAGCTCGGCGAACAGCCACGGCCGGCCCAGACAGCCGCGGCCGATGACCACGCCGTCGCACCCGGTGGCGGCCATCATGGTCAGCGCGTCGCTGGCGTCGTAGATGTCGCCGTTGCCCAGCACCGGAATGGTGCGCACCTGCTGCTTGAGCAGGGCGATCTGTTCCCAGTCCGCGGTGCCGGAATACCGCTGCGCCGCGGTGCGGGCGTGCAGCGCGACCGCCGCGGCACCCTCGGCCTCGGCGATGCGCCCGGCATCCAGATGCGTGTGGTGCTCGTCGTCGATACCGATGCGGAACTTGACGGTCACCGGTATCTCGGTGCCCTGCGTGGCGCGCACCGCCGCGGCCACGATCTGCCCGAACAGGCGTCGTTTGTAGGGCAGCGCCGAGCCGCCGCCGCGCTTGGTGACCTTGGGCACCGGGCAGCCGAAGTTCATGTCGATGTGATCGGCCAGGCCCTCGTCGGCGATCATCTTGGCTGCCGCGTAGGTGGTGGCCGGGTCGACGGTGTAGAGCTGCAGCGACCGCGGCGACTCGTCGGGGGCGAACGTGGTCATGTGCATGGTGGCCGGGTGCCGCTCGACGAGCGCGCGTGCCGTCACCATTTCGCAGACGTAGAGTCCGCTGACCGTCCCGACCAGCTCCCGCTCCAGCTCACGGCACAGGGTGCGAAACGCGACGTTGGTGACCCCGGCCATGGGAGCCAGCACCACCGGGCTGGCCAGCTCGATGGGGCCGATACGCAACGCTGGTTACCGCCGGCTCATTGTCAGCGTGCCCGCGGTGGTGTGCAGCTCCAGCGCGGTGGTCCGCTTGCCGGTGCGGGCTTCCCGCTCGAGCTGGCGCCGCTTGGAGATCTCGAACTTGTCGCACGTCGTCTCGAGCTCCTTGATCAGCAGCGCCAGGTCGTCGCGCAGCGCGGCGGCCTCGCCGGTGAAGTCCTCGCGCTCGAAGATGCGCCACTTCTTGAGCACCGGCATGACGACGTCGTCGAGGTGGATGCGCGGGTCGTAGACGCCGCCGACGGCGATCATCACGGCCTTGCGCCGGAACTCGGGCACCTGGTAGCCGGGCATCTGGAAGTTGCGCAGCACCTTGTGCAGCGACTTCATCGCCTGGTTGGGCGCGATCGCGAAGCCGGCCTCGCTGACGTCGCGGTAGAAGATCATGTGCAGGTTCTCGTCGGCCGAGATCTTGGCCAGCATCTGGTCGGCGATCGTCTCGTTGCAGGCCTTGCCGGTGTTGCGGTGCGAGATCCGGGTGGCCAGTTCCTGGAAGGTGACGTAGATGACCGAATCGAACAGGCTCTCGGCGAACAGGTCCTCGCGCACCTGGTGGTTCTGGCCCGGGCTGAAGCCACGGTTGACCACCTCGATGCGCAGCTTCTCCAGCTCGACCGGGTCGACCGCGCGGGTGACCACCAGGTAGTCGCGCAGCGCGATCCCGTGCCGGTTCTCCTCGGCGGTCCAGCGGTTGACCCACTGCCCCCACGGGCCGTCCATGCCGAAGTTCATCGCGATCTCGCGGTGGTACGACGGCAGGTTGTCCTCCGTCATCAGGTTCTGCACCATCGCCACCTGGGCGACGTCGGAAAGCTTGGACTGGCCGGGTTCCCAGTCCTGCCCACCGAGCGCGTAGAAGTTCTTGCCGTCCGACCACGGGATGTAGTCGTGCGGGTTCCAGTTCTTGTGCATGCTCTCGTGCCGGTTCAGGTATTTCTCGACGAACGGCTCGAGCTCCTGCAGCAGCTGTAGGTTTGTCAGCTCGGCTGACATAAGGCCTCCAGTTATCTGTGTCGATGGGTAGCACTCAATATATCTGTGTACCTCAGTAGCATCAAGTTCCTCGTCCGGCGCGGCAAACGGCGATTTTGGTGCCGGTTTCCGGGCCAGTCCGGCCCCGTGCGGCCGTGCCGGGCCCAGCGATACGGCTTGCCGATCCGGCCGAGATGCAAACCCGCTACTGCGATTTGCCGAGCTCGCCGGCCGACACGTACGGGGCGGCGGTGATGTAGAGCATGTTGGTGCAGTAGTCGATGAACTGCTTGCGGGTGGCTCCGAGCTGACCGTGCAGGTAGGCGGTGAACAGGCTGGACAGCCCGCCCACCAGGCTGGTGGCGATCATCTTCTGCAGCACCGCGTCGCCGATCCGGGACAGCTTGCGCTGCAGCAGGTCGATGAAGTTGGGCATCCACTCCGCGCCGGAGCGGGTCAGCACCGGTTCCACCGCCGGCGCCAGCAACAACACCCGGCCGCGCACCGGGTCGTCCACCATCAGCTCGACGAACCGTTCGACCGCCTCCCGCGGGGTGGTCGCCGACGTCAGGGTGTTCATCGCGCGGGTGCACACGTCGTCGTAGACCGCGCGCACGAACTCGTCACGGTCGGTGAAGCTTTCGTAGAAGTAGCGCTCGGTCAGCGCCGCCTTGCGGCACACCGCGCGCACGGTCAGCGCCGGGCCGCCGGAACCGCCGAGCAACTGCACCCCGGCGTTGATGAGGTTGTCGCGGCGAAGCGCGAGGCGACTCTCCAGGGGCACGCCGGTCCAGCGGCCCCGTCGTTGACCCGTCTGCACATCGCTCCTAAGCTGAAAACTTGACAACGGTTGTAGTCAAAAATTCACATACCCACAGGAATCCAATAGTGACTCAAGATACGTCCGCATCGCGCCCCCTGACCAGCGACGTAACGGGCAGCGATGCGGCCGGTCGCACTGAGCAGTCGATTCCGGCCCGGCCGGCGGATGCCGGCGCCGCGCTCGCCGGCGGCTGCCCGGTTTCGCCGCTGGGCTATGAGGCCCCGCCCTCGCCGCTCGGCCCTGACTCGCTGACCTGGAAGTACTTCGGGGACTGGCGGGGCATGCTGCAGGGCCCGTGGGCCGGTTCGATGCAGAACATGCACCCGCAATTGGGCGCGGCCGTGCTGGACCATTCCACCTTCTTCCGCGAGCGCTGGCCGCGGCTGCTGCGCTCGTTGTACCCCATCGGCGGCGTCGTGTTCGACGGCGATCGCGCTCCGATCACCGGCGCCGAGGTGCGCGACTACCACACGGACATCAAGGGCGTCGACGAGCAGGGCCGGCGTTATCATGCGTTGAACCCCGACGTCTTCTACTGGGCGCACTCCACCTTCTTCGTCGGCACCATCCATGTGGCCGAACGGTTCTGCGGCGGCATCACCGAGGAGCAGAAGCGGCAGCTGTTCGACGAACACGTGCAGTGGTACCGGATGTACGGCATGAGCATGCGCCCGGTGCCCAAGTCGTGGGAGGAGTTCCAGGAGTACTGGGATCACATGTGCCGCAACGTGTTGGAGAACAACGAGGCGGCCCGGGCCGTGCTGGATCTGACCGAGTTGCCCAAACCGCCGTTCGCGCAATGGATTCCGAACCGCCTGTGGGCCGCGCAGCGCAAACTGTTGGCGCCGTTCTTCGTCTGGGTGACGGTCGGCCTGTACGACCCGCCGGTGCGGGAGCTGATGGGCTACCGGTGGTCGGCCCGCGACGAGTGGTTGCACCGGCGCTTCGGCGACCTGGTTCGTATCGTGTTCGCCTTGGTGCCCAGCAGATTCCGCAAGCACCCGCGGGCCCGCGCCGGACTGGACCGCGCCAGCGGCCGGATCCCGCTCGACGCCCCGCTGGTGCAGACCCCGGCGCGCAACCTGCCGCCCGAGGACGAACGCGGAAATCCCAAGCACTACTGCCCGATGGTGTCGTAGCCGGGCGCCGACGGGCTTAGGCGTGGGCGTGCTGGTGCACGTCCTCGAGGCCCGCCTGATGCACGTGCCGATGGGTGTGTTCGGTGCCGTCGGTGTGCGCGTGGCTGTGCTCGTGCTCGACGTGGTCGTGCTCGTGCGTGGTGTGCGCGTGCGCGTGCGTCACGCCGCCGTGCTGATGTTCGTGCGTGTGCGGTGCGTCGTGGGTGTGCTGTTCGCTCATCATGTTCTCCGTTGCGTGAAATACCTTGCATGAAATAAGTTGTGCCGCCGGCTGACTCAGCGCGCGGCGCCGCGCGGCCGGTGGCGTGACGATGCGGCCACCGACTTGAGCCCGCCCTCGCCGCGGTGGTGACCCGGCACCCCGGGACCGGCGTGCTCGGCGTTGAACACCGCGTCGATCACCAGCTGGCGAACATGCTCGTTCTCCAGGCTGTAGAAGATCGTGGTGCCCTCCCGGCGGGTGCGGACCAGACGGGCCATCCGCAGCTTGGCCAGGTGTTGGGACACCGACGGTGCCGGCTTGCCCACGTGCTCGGCGAGTTCGTTGACCGACATCTCGCGGTCCGTCAACGACCAGAGCACCTGCACGCGAGTGGCATCGGCCAGCATCCGGAAGACCTCGACGACCAGACGTACCTGGTCGTCGGGCAGCCGACCTGCACTACTATCTGCATGCATACGCAAATACTAGCGAAGCTCGGCCGGTCTGCCAAGGCGCGGCTCAGTCCGACGGCACCACCGTCGACCGGCGCCGGCCGCCGTTGCGCTCGTTCCACAGCCGGTAGACGTCCACGGCGTCCGGGTGCGGCTGGTAGCGCATCGGAAGCCGGCGCTCGTCGAACGGCTTGGCGAATTCGGCGTAGAAATTCGCCAATTCGAAGTACTTGCGGTCGTCCACGTAATACGGCTCGTAGCTTTCCCGGGTGGTCAGAAAAATGACTTCTCTGGGCGAGCAGTAGTACAGCGCGCCCAGGCACATCGGGCACGGGTGCGCCAGCACATAGATGGTGGCGTCCACGAGATGCTCGGTGCCCAGCTTCCGGCAGGCCGCACGGATGGCCAGGATCTCCGCGTGGGCGGTGGGGTCGTTGGTCTGGGCCGCCTTGTTGGCGCTCTGGGCGAGGACCTCGCCGTCCTGGACGATCACCGTGGCGAACGGGCGGCCGCCTTCGGCCACGTTTTGGCGGGCCAGGTCGATGGTCCGCCGGGCGAAATCGGTCACGAATTGCAGGGTAGTCCGCGCGGCCTCGTGCAATCGGCCCTGTTTTACTGACTAGATCGTCTATTCAAATCCGGGATGAGGAACACCATGGCGCGCACCGACCGTGATCGTTGGGACCTGGCGACCAGCGTCGGGGCGACCGCGACCATGGTGGCGGCCCAGCGGGCGCTGTCCTCGGATGCGAACTTGATCGACGACTCCTACGCCGCACCGCTGGTGCGGGCGGTCGGCATCGACGTCTACGTCCGGTTGGTGAACGGGGAGATCCAGCCCGGGACGTCCGAGTTCGACCCGCATCGCATGGCGAGGGGGATGGCTTGCCGGACAAGGTTTTACGACGACTTCTTCCTTGACGCCGCCCGCGCCGGCGTCGGCCAGGCGGTGATCCTGGCCTCGGGACTGGACGCGCGCGCCTACCGCCTGCCCTGGCCGGCCGGCACCGTCGTCTACGAGGTCGACATGCCCGACGTGATCGAGTTCAAGACCCTGACGCTGGCCGACCTCGGCGCGCAGCCGACCGCGCAGCGGCGCACGGTCGCGATCGACCTGCGCGACGACTGGGCCGCCGCGTTACGGGAAGAGGGGTTCGACCCGCAGGCTCCCGCCGCGTGGAGCGCCGAGGGCCTGCTGGTGTATCTGCCGGAACAGGCCCAGGACGCGCTGTTCGACAACATCACCGCGTTGAGCGCCCCGGGCAGCCGGCTGGCTTTCGACTTCGTGCCCGACACCGCCGTTTTCGCCGACCCGCGCTGGCGCGCCCACCACGACCGGATGAGCGAGCTCGGGTTCGAGGTCGATTTCAATGACCTGGTCTACCACGGCGAGCGCAGCCACATCGTCGACCACTTGAGCGGGCGGGGCTGGCAGGTCACCTCGAGGACGATCGCCGAGCTGCATGCGGCCAACGGCTTCGCCTACGCCGCCGACGACGTCGCCGCGGCCTTCGCCGACGTCACCTACAGCAGCGCCGTGCTCGGCGGGTAATACCGAGGCCGCCGGCGTGCAACTGTCACGCATCAGCCGACGTCATATACGTCTGGTGCCCCCACTAGGACTCGAACCTAGGACCTGCGGATTAACAGCCGCTAGGTGGAACGCACTTGCCGTCGCTGCATTGTCCGCCAGTGATCCCGCAGCGGCCACAGAAAGCGCTTCTGAACTGGGCAGAAAGGGTAGTCACGGTCTAGCAGGTGCTGTGTCGCGCGTTCGCCCTGTTCGGCACGTCGCGCAAAGTCTGCTGACACGCTGCTGACAAGTCCGCCGCGCCGCGCTGAAATTGGCAGGCACTGTCATGGGCCTATGGCACGATCGATGCGTGGACCCGCTCACAATTGTTGTTGCAGCTGTTGCTCTCGGAGCGCAGGAAGGCGTACGGGAGACGGTGGCGGCTGCCGTCAAGGACACCTACGCCGGGCTCAAGCGGCTCATTACGGACCGCTACAAGGGCGTCGACCCCACCGGCGTCGAGAACAAGCCAAGCTCCGAAGCGAAGCGGGCCTCGCTGGAAGAAGACCTGAAGGATGCAGGCGCAGAGCAGGACGCGGACCTCTTGGCTGCGGCGAAGGCGGTCATCGAAGCCGTCCGCGCGGACAATCCCCAGGCGGGAGAACCAATTGGGGTCGACCTGGAGAGGATCGAAGCGGAAGCGCTTCGTATCCAGAATGTGCAATCGACCGGTGGGGGAGTTCGCGTTCGCGATGCAAAGGTCGCCGGGGCTATCGATATCAGCGGTGTGTCGTCGGGCCAGACGGGACCACCGGCCACCCCTTAGCGGGCGCGGCAGCATCTGAAGGTTCTGCTGCCGCGCCGTTAGTGCATCTAAGCGGTAACACTGTTGGCCGTGATCTCAACGTCACTCTGGGCAATCCATCGGTCTACGAAACGATGGGGCGGGACGCGTACCTTGCTCGGGCTTTAGAAGATTCGGATTCACGGATCGAACGGCGACGGGCTGGTGCGGGTCTCGACGAAGCTCAGGTTGCGCGGATTCAGCACCTCCTACCTCAGGTACCTCACCAGTTGAGAGGGTTGTCGAGCGGTCAATTCATCGTTCTGACAGGCGCATTGGGAACTGGCAAGTCGGACAGAGCCGAGGGCTGGATTCGTAGTGCGGCAGAGTTGGCGCAGAGCGATCCCGATGCTCCGTTACCGGTTTGGGTTGCCATAGACGACCTCGAGTCCTCGCTAGAGGTCCACCTCCAGCGCGAAGTCGGTGTACTGGCGCTTGAAACTGTCGGCGCAGATATCGTCATCGACGGCCTAGACCAACGCGCAGACCGTGCCGAAAGGACCATTGGCTACGCGGATTCGCTTACACGACGGTGGCCGCGTTCGCGCGTTGTCCTGACATCCCGTGCAACACACAATGTTCGCGACAGCGTGGTGATCCGAGTCGACCCAATGCCGAAGTCTTATGGTCGGAAACTGGTGAGCTTGGTGGCCGGTACAGCACAGGTCGGCGACCTGCGACCTGAAATCGAGGAAGCTCTTGAACGGCCTCTGTTCGCCTTGTTGATCGGACAGCAGGCCAGTTCGGGCGAACTCACCACGATGACGGAAGTCATTGAGGGTGTTGTCCGCAAGGTCGTTGGGAGGGAGGACAAGGACCTTTATCCCCACCTACGGCAATTGGCCATCCGAACAACAACGACTGCACGTCCCGTCGACCCCGAGAGCTTTGTTGACTTCGATGTGGCTTCCAAGCTTCGAGATTCGCCGTTCCTGACAACGACAGCGCACGGTTTGTCATTCTCGTTGGCAACCTTCGAGCAGTGGTTTGCTTCGCGGGCCGTGCTCGAAGAGGCTGTTTCACTGGACGACATTCTGGTGGACCTGCCGTCGTTCGACCGATGGAAGTACGTGCTGTCAATAGTGCTCGCGTCTGGTGAACCATCACGAGTAGATCCAGTGATGGCGCGCATCGCGCGTTGGAACCCTGGGGCAATTGGATGGATCATCAACGAGACTGAAAGCGCAGGACTAAACCGATACAGGGAAGATTCGTCAGATTCCCAGCAGCAGATGGGTTACCGCCTGCGGTTTGCACTTGAGGCGATGCTCGACGGTCTAGGGCCACTGTCCGCGGCCTTCACACCTTTTGCAACTACCGGCCTCGACTCGTTGGAGCACTTCTCCCTTGGGCTCGAATACGGCGGTGAGAGGGTCAGCACTACATGGCTCATATCGAATCAGGTCCCAGATAACCCCCTTCCGCCACTAATTGACGCATCGGTTGAGGTATCCACCAACCGTTGGTTCTCTATCGAAACAGCCGCAATGCCCGCTTCGCGGAACTGGGTGTGGGCTGCTGCGCGAAACATCTTGGCGGGCGACCTAAGCGAGTGTCTAACGTCGGTCGCCATCCGCATAGCCAGCCAACATGACGGTGTTGTGCGGCGCGAGGTGGAAGATCTTCGGCGAAGGAATGTAACTGACCCAACGGATCTCGACGACATCGGTCGCGGCTTATATGGCAGTATCTACCCGCTGCCTGACGTTATGCCGGGTCGGAATGGCTGGCCCGGGTTCTCGCTGGAATCCGTGGCGAAACGAGTCCGCGCCGTCATCGAAGCCGCGATCCAGTGCTACATCGAGCTTTGCGATAGTGTTGCGCCAAACTTCGGAGATACGTTGGCACACAAGGGAATGATGCCTTTCGAGTATTATGCTGATATGTCCTACGGGGGTTCGGGTAGCGGTGGACCGTTCTCATTAGGACCTGCCGAACCAGGAATCCGTTGGCTTCTCCGACCGATTGGGACGCCGCTCCCGAACGGTCAGCGGCACGGCAACAACGCAGTGAACATCACGATCAACGATGAGACGCGGTCAGCCGAAATCCGAGACGACAAGCAAGCTTTTGGTGATGCGTACTTTGAGTACATCGCTAACACGCCTGGCCTGAAACCATTCTCGGATTCGTTCTCGATCTCCACAGGTCGATTCGACATCATCGACAAGAAGCCAGCCACGCACATCGCGGTAGGTTGGCTATGGGACGATCTCAAGAACCTGAAGTGGGTGTCCGGCCTGAAGCCGAACGACAGGACAGAGTAGACGGTGGGTTATTCATCCCGCCGAACGACGCTTCAACGGAACAATTTTGGTGCTGGCGCCTGCTGTTCCCCGGCCTACCTTCGGCGCCACCAGTTCGTCTTCGGTGATGTAGTCGGCGTAGGTCGATAGCGTCAGTACGAAACTGGAGTGTCCCAGCCACTTCGACACCTGCATGTAGTGCTCCCCGGCGCTCAGGTTCATGGTGGCGAACGTATGCCGCAAGTCGTGGAACCGTACGGATCCTAGGCCGAGTGCCGCGCAGGCGGGCTGAAGGTAGTTGTCGTACAGGTTGTCGGCCACCACTGGCTTAGCCCAGTCAAACGCCGAGCGGCTGCGCCGACCAGGAAATAGCGGCGCGTGCGGTATGTGATGCCTCTTGCCGTTGGTGTCGCGCAGCTTGCCGGCGAACGGGTGAACCTTAGTCAGGTGGTCGCGTAGCTCGTCGGTCAGCCACGGCGCGAGAGGCACTACTCGATCCGTTGAGGCGTCGCTTTTCGGCGTGCCTTCGACCCACTCAAGCGGAGCGGTTGCCTCTGAGCCCTCAGGCCTTGCCCGCTTCATGGTGCGGACAATCCGGATACTGCCGACCGTTCCGGGGATATCCGATAGCGACACATCGCCAACCTGCAGACCCTGGAGCTCTGCGGCCCGGACTCCGGTATGCGCCGCGAACAGCACGGCCAGCGCGTACACCGCGTTACCCTTCTCGCGAGCGATCCATTCATGCACCGCCGCTACCTGATTGGCGGTCAGCGGGTGATGTGCGAACGGCTGTGTACCTGTGGCGGTCCTGCGCTTAGTGGTTCGACGCGGGCCAGGAAGCACCGGGTTGGATGTCAAGGCACCGTCCCGTACGGCCACATCGAGTATCCGTCTAAGCGTTCCGACGATGTGCTTGACCGTCTTCGGGCTGCGGTGCACAACCGGGGCGGGGGAGGCGGGGCGGCTCGGATCGGCCTTCCCTCGCGTGACAAAGCTGCGCCGCTCATGCGGGGCGAAAAGTCTTGCCCGAAAGCTGTCGACATCTGCAGCGGTGATGGCCGCGACAGGCTTGCTACCGAACACCGGCGCGATGTGCGTGCGGTACAGCTTCTCGTAGCCTTCGATGGTCGTCGGCTCCATCTGCCCCACGAGGCTGTTCAGGTACTGCCGGGCATAGGTGCCCAGCGGCGTGTTCGCCTTCGCCTTGACGCTGCCGGGATCGATACCCTTCGCGCCGTCTAAGGCATCCTCCACCTTCCTCAGGCGTGCCTTCGCCTTACGCTCGGTGTCGAACGTCTCGGACGTCTGCCTTGTCTTGCCGGTCGGTGCCCCGACTCATCGCGCACGGGCTCACGCTTGCTGTGCTCATGTTCTCTCCGGGTGTCGGTGGCAATGTCAACTTGAAGTGGCCCCAGTGTGACGGCTAGTTTTGGCCCCCCCTTCGCGGTGCGTTGGGATTTTCTGGCGTTGAGGTGGCTAGCCCCAGAAGATGCCTGAGGGGTTGTGATCGATTTCGGTGAGCACATCGTGGATGTGCGGTGTGGGGTCGATCGTGTCGTAGCGGTGAAATTTGAGGTGTCGGTCTCGCCAGTACAGGGTCCAGGTGTTGGTGGTGGCGGTGTAGCGCAGTCGTGCGATCGGGAAACTGGTCCAGTCTGGACCGTAGTCTTCGCGCCACGGCGCTCGTCGTTCGACGATGGTGAGGTGCCGGGCAGCGACGTCGCATTCGACGCGGACTTGGTGACGCGCGTGTTCGGGCACTCTGGCCGCGCACCACTGTTGCACGCGTGCGATATCGAGTTCGGGTAGGGCCATTGGGTCACCACCGGGGCGTGTCGGTGGCGGCGGTCAGGGTGTCGTAGGCGGTGTCGAGTTGGCGTTGACGGCGGCGGTGGGGTTCATGATTGGACTCGGCAGCCAGAGCATCGATCAGGTCGTCGAGTTCGGCGGCGGTCATCGTGAGATGAAGCTCGCCGCCGTGGGCGCAGATCGCGAAAACCGCTCTCTGACAGTTGTTGTCGAGGAAGGGCAGGGTGCGCAGGGTCGCTGCGGTGTCAGCGTCGATGGGAATGTCGCGGCGCGGTTGGGCTGCGGTCAGTTGCTGGCGACGCAGATCGTAGATTGATGCTGCCCAGTTGCTGATGGTGCCGTCGTCGCCGCAGTGGCTGCATTGCCAGCCGATGGGTTGCTCAGCATCGCCGCGGACCACCGTGATGCGGCCCGGGCAGCGGCGGTTGGCGGGTCGGCGCCGACACGGCAGCGCGGTTTCCCACCGGGTGTGAGCGTCGCCGGCCGACGCTGCGGAAACGATGCCGCCCAGGTGCTCGGCGAGCGCACGGGCCGGCCCGGGGGTCTCGGGGCCCACGTCGAGGAAGTGCTGCAGATCGGCGACCAACATGACCTGGTCACTGTATCGGCTGCAGGCCGGCCAGAGGCGCGTGAGTTACTGCGCGGTGCTGGTGCGGCGGGTGCGGGCATGGGCGAGTCGGTAGGAGGTGGTGCCGGTTTCGATGATCTGCCCGGCGAAGGTCAACCGGTCGACGATGGCCGCACACAGTCGCGGGTCGGTGAAGGTCTTGGTCCACGCGGAAAACGGCTCGTTGGACGCGATCGCCACCGAGGCGCGTTCCTCGCGCTCGGTGAGCACCTGGAACAGCAACTCCGCACCGCGGCGGTCCAATTGCAGGTAGCCCAGCTCATCGATGAGCAGCAGATCCACCCGACCGTAGCGGGTGATCAACTTACTCAGGTGGGCCTCGTCGGCGGCCTCGACGAGTTCATTGACCAGCTTGCTGGCCAGGGTGTAGCGGACGCGGTAACCGGCTTCGGCGGCGGTGGTTCCCAACCCGATCAGCAGGTGAGTCTTGCCGGTCCCGGAGTCGCCGATCAAGCACAAGGGTTCACCGGCTTTGACCCAGGCGCAGGTCGCCAGGGTGCCGATGACTGCGGGGTTGATCGCGGGGTTGGCCTCAAAGCTGAACTCGTCAAGCCGCTTTGGCCGAGGGAACCCGGCGTCATGAATACGGCGCTGCGCCCGGCGGCGATCCCGGTCCTCGCATTCGGCGATCATCAGCTCCGATAAGAACCCCAGATAGGACTGCTGTTCACGTTCGGCCGCGGCGGCGATCTCGGCGAAGCGGTCACGGATGGTGGGCAGCCGCAACATCCGGGCGCCCTGTTCGATTGCCGCGACCGCGGCCTGATCGGTGACGGTGTGACGCGCGGTGGTGTTCATGAGCTCTGCTGCCCCAGCAGCGTGTCATAGGGGGCCACCGACGGCAACGGCCGCTCGTCGGCGATCAGGCGGTGCTCAGCGAGCCGGAGCACCTGGGCGCCCTCACCGCCGCCGGGTGGCGAACCGAGGCCGGCGCGCTGTTCGGCGGCCCGGCGGGCTTCCAGCGCCACCACATCGGCATTGACCGAGCCCACCGACAGCGCAGCGCTGATACCGGCCAGCACATCAGCGCGGTCGAGGTGACGGTGCAGCAGCAGGACTTCAACCAGCACACGGGTTCCGCCAGCATCCCCATGAACCCGCCGGGCTGCGGCCCACCACGCGTCATGTTCAGCGGTGAACAGTTTGGCCGCCCGCGCTTGAGCCAGTGCGGTGGCCCCGGCAACGCGCCGGGTTTGCGGGCCAGGATCTCCAGATAGTGGTCCAAGTCCAGCACCTTGGTGCCTTTGCCGACTGCCCGGGGATGACGTGCCACCACCGTGGTGCGGTCATAGACAGTGACATGCGACGCCGACAGTTTCACCTGCACACGATGCCCGATGAACCGGGCCGGCACCGAATACTGATTGCAGCGCACCATGATCTGGGCGTACCGATCCACCCGCGGAGTCAGCGTCAACGCCGTCTCAAACCCCTGATCGGCAACAGGCTGCAGGAACTGCCGCTCGGTTTCCCAGTCCTGGCCAACACTGTTGGCGCGGTTAGCGATCCGACGACGATCGTCGGCGTCGTCAGCAGCGGCCAAGAAGGCGTTGAGCTCGTCGATGGAGTCGACCACCGGCATCGGCACGCAGTGATTGCGGCGAAACCGGCCCCCTTCGCCTTCCACGCCGCCCTTTTCGTGGCTGCCGTCGTGACCGGGCTGGCAATACCACGCTTCAAAGCCGTAGTGCGAGCGGAACGCGATCCAGCGTTCATTCTCCTGACGGGACCGTCCGAACAACACCTGCTTGACCGCACTATTGAGATTGTCGTAACGGATCTTGTCGACCGGCACCCCGCCGAGGCGGTCGAACCCGTAAACGTGGCCCTCCAGAAACGCTTCCTGGCCCTGGGTGGCGAACGCCCGATGCGCTGCTCGCCCCGAGAACGACAACCGCATCGTAAACAGTGCGGTCTTGGTCTTCACCCCGGCCAGCATCACCCACAGATCGTGGAAGTCGACCTCGGCTTCAGCGCCGGGTCGGTAGGTCTGCGGCACAAATCCCGCCTCCAAGGCCCGGCCCGCCTCCGCAGCGATCTGTGGGCGACGTTTGCGGATGTGGTCGCGCACCGTCGAATACGACAACCCGGCAGCGTCATGCTCATCGACCAGCCGCGCCAACACCCGTCGCGCGGTATGGCGTTGCTTTTTCGGGGCATCCAGATCCGAACGCAGCATCTCATCGATGGCCGCCTTGAACGGCTCCAACCGCGGCGCCGCTCGCGGCCCGGTCTTGCGCGGCGGCGGCACCGCCGAATCCAACGCTTGGCGCACTGTGCGTCGATGCACCCGGTACTTATCTGCCAGCGCCCGGATCGACAAACCCTCAACCCGACGATCCCGGCGGATCGCTGCGAACTGCTCCACCCGTGTCCTCACCTTTCCAGCCACCAACCCTTCACCAGCGATCCGGGCCATCCGGAACCGCCTGTGATCACTGTCAGGTGGGGCCAATTCACGCCGTCATAACCGACGCGGCGTGTCGTCAAGGTGGGGCCAACTCAGACCGTCACAACAGCACACCCGCGACCACACAGGTGGGGCCACTTTCGACCGCCCACCCGGGGCCAAATCAGGCTGTCACAGCCAGGGTGTCGGTTGTGGCGAATGACGAGCGTCACCCACCTCACCGAATACTTATAGCCGACCGCTCTACCTCGAAAGATGGCTCGAATTAGGGCCTGCGGTACTTCCTGTGACCCCGACCGCCGTCCTCTATCGCTCGCTGCTCGAACACGCCAGCTTGCCGGTTCGCTTCGTTCGCCAGGCGCATGGCGAACTCGCCGGTGATGTGCACCTCGCGTGGCTGCTGGCGCTTCTCGCGGTCGAATTCGCGCGACCTGCCCTGTCCAGCGGCCCGCCATCCCAAGATGACTGGGGCTGCTCATCAGCTGGCCAATCGGCGCTAACGCTGCTACTGCCTTCCGGGCATGTCCGCGCGCGCAGTGTGTCCGGTTCGGGTGCGGGTTGGGTGTGCAGGGTCGGTGGTCGGCCTAAGGACGCAACGTCACTTTGGGTGAAAGATTCGGTGCTGTTGCCGGCTGAATCGCCGTAACCTAAAGCGTCATTAGGCCTTCCGCCAATGCTGTCCCATACCTGCTCGAAGGGCGATGGCTGTTCGCCCTGGGACAGTACAACTTCCGCTGGTGGCTTTAGGCCAGCGCGGTCCAAGCTGTTTTGGATGGCCTTCAGTTGCACATCGGGCGGCTTGGTGTCGTCAAAGGCGAACTCAATGAGCTTTCCCATCAGGCGGTTTGAAGCGTTCTCCACGCGGATGCGCGCAGCCTCCCTTGACTCTCTTGGTCGCGCCACCATGGGTCCGGCATACCGTGCTACCGTAAATCGCAAACTTTCGGCACCGTTCGCCCCGGCTATTCGTTGCCACACACCTCCTCTCCGGGTTATCAGCTAGGAGCGTGTCCTGCCGATTGGGCAGTTCGATGGCTTCAGAGTTTGATGCATCGGGTGGAATGACAGCCGGAAGGCAGTCGCTCTCACGGATTTCTTCGGCCTCTACGTCGATGATGTTGTTCTCGTCATGGTTCATCGCGCCAGTCCCTTCTTGGCAGATCGCGGTCGTGCATCTCTGGTCCGTTGGTGTTGCGGGTGCCGCATCCTGGCGCAAACCGCCGCCAGTGCCGCCAGGCAGCGCGTGCTCTGACTTGGGGTTTGCGGAGCTTGTGGATCTAGCGGATTGTCGGCAGAAGGCGAAGACGGGCCTCTGCGGCGGCTCAAACTTCATAAGTTAAAACTCAACTTTCGTGCTCTTGAGAATTGATTCATCATCGATGTGGTGCCCGTTGTTGGCGGCCGGTGCTTGTGCTTGGGTTTCGGCTTCAGGTTCCTTGACGTACCGAGACCAAGCATCCTCGAATGCGGCGAGGTAGTAGCCCCTGCTGTTGGCGTCGGTACTCCATGTCCATGGCCATGAGAAAGTCCCCATCTGTGGCCAGTAGGAAGTCCCCACTGGTGGCCAGGTAGAAGTCCCCACTCCTTTGCGGGCTCGTCGTGTCTTTTCCGGGAGCTGAGGGCCTGGGCGGTGACGGTGATAGCGCCAACTGTCACTTGATCACCGCCCAGGGAGCTCTATTGAAGTCTGCAAGGGAGCGTATGAACATCATTTCGGCGTATCACCAGGTCGGGTCGTATCGCGGCGCGGCCGAGCTGTGCGGTACTACGCACAAGACGGTCAAGCGGGTCATCGAGCGGGCCGAGGCCGGTGGCGCGCCCCCGCGGGAACCACGGCCACGCAACCTCGACGCGTTCACCGATCTAGTCGCCACCCGAGTCGAGAAATCACACGGCAAGATGTCGGCGAAGCGGATGCTGCCGATCGCCCGAGCTGCCGGGTATCAGGGCTCGGCCCGTAACTTCCGCCGCCTGGTAGCCGAGCAGAAAGTATTGTGGCGCAACGCTAACCGGCATCAACGCCGTCCGGCGGTCTGGTCACCCGGTGACTATCTGGTGATGGATTGGGCCGAAGCTGCACCGGGGTTGATGGTGTTCTGCGCGGTGCTGGCCTATTCGCGGTGGCGGTTTGTGCGGTTCGCCGCCGACGAGAAAGCCTCGACCACGCTGGCGATGATCGCCGAAGCCCTCGAGGCGATCGGTGGGGTTCCGGCCAAGATCCTGGCCGACCGGATGGGCTGCCTCAAAGGTGGTGTCGTCGCCAATGTTGTTGTTCCAACACCGGATTATGTGCGATTCGCGTCCCACTATGGCTTCGTTCCGGACTTCTGCCACGGTGCGGATCCGCAATCGAAGGGCATCGTGGAGAACCTCTGTGGCTACGCTCAGGACGACCTTGCGGTGCCGCTGCTGACCGAAGCTGCGTTAGCCGGTGAGCAGGTCGACCTACGTGCCCTCAACGCCCAGGCGCAACTATGGTGCGCCGAGGTCAATGCCACGGTCCACTCGGAGATCTGCGCCGTGCCCAACGATCGCTTGGTTGACGAGCGCACCGTCTTGAGGGAGCTGCCCTCGCTGCGGCCGACGATCGGCTCGGGGTCGGTGCGCCGTAAGGTCGACGGCCTCTCGTGCATCCGTTACGGCTCAGCTCGTTACTCGGTGCCTCAGCGGCTCGTCGGTGCCACCGTGGCGGTGGTGGTCGATCATGGCGCCCTGATCCTGTTGGAACCTGCGACCGGTGTGATCGTGGCCGAGCACGAGCTCGTCAGCCCAGGTGAGGTGTCCATCCTCGATGAACACTACGACGGACCCAGACCCGCACCCTCGCGTGGTCCTCGCCCGAAAACCCAAGCAGAGAAACGATTCTGCGCATTGGGAACCGAAGCGCAGCAGTTCCTCGTCGGTGCTGCTGCGATCGGCAACACCCGACTGAAATCCGAACTCGACATTCTGCTCGGCCTTGGCGCCGCCCACGGCGAACAGGCTTTGATTGACGCGCTGCGCCGGGCGGTTGCGTTTCGCCGGTTCCGCGCTGCCGACGTGCGCTCGATCCTGGCCGCCGGCGCCGGCACCCCACAACCCCGCCCCGCCGGCGACGCACTCGTGCTCGATCTGCCCACCGTCGAGACCCGCTCGTTGGAGGCCTACAAGATCAACACCACCGACGGGACGGCCTCATGACCACCGCTGCCAAGCCGGTGGCACCGTCCTCGGCGGCACCGCTGGCTGCTGACCTTGACGCGGCGCTGCGGCGGTTGAAGCTGGCCACGGTGCGCCGCAACGCCGCCGAGGTGTTGCAAGTCGCCAAGACGCAACGCTGGACACCGGAGGAGATCCTGCGGACGTTGGTTGAGGCCGAGATCGCTGCCCGCGATGCCTCCAACACCGCCAACCGTCTCAAGGCCGCAGCCTTCCCGGTCACCAAGACCCTCGACGGGTTCGACGTCACCGGATCGTCGATCACCGCAGCCACGTTCGACTACCTGTCGAGCCTGGAATGGATTCGGGCACAACAGAACCTGGCGGTCATTGGCCCACCTGGTACGGGCAAAAGTCACCTGCTCATCGGCTGCGGGCACGCTGCCGTCCACGCCGGATTCAAAGTCCGCTACTTCACCGCCGCCGACCTGATCGAGGTCCTCTACCGCGGCCTGGCCGACAACACCGTCGGCAAGATCATCGACACCCTGCTCCGCGCGGATCTGGTCATCTTGGACGAGATCGGCTTCGCCCCGCTCGACGACACCGGGACTCAACTGTTGTTCCGGCTCGTGGCTGCCGGCTACGAGCGCCGCTCCCTGGCCATCGCCTCGCATTGGCCCTTCGAACAATGGGGGCGATTCCTGCCCGAGCACACCACCGCCGCCAGCATCCTCGATCGGCTGCTGCACCACGCCAGCATCGTCGTCACCTCCGGCGAGTCCTACCGGATGCGCCACGCCGACCACAAGAAGGGAGCCGCCAAGAATTAGCCAACCACCCGCAGCGGAGTGGGGACTTCTGCTGGCCACCAGCGGGGACTTCTACTTGGCCATTGACATACTCCACCAGATGTTGGTGCTCTTGATTCCGTAGGGCTTCAGCAGTTGCGATAAGTCCCTAGAGCCAAGCGGAGTTCCGTCACGGCGGTAGCTTTTCCAGGGTGATTCATCAAGGCTCTCAAGCATTTTGAGGAGTTGCGGCGTCTTAAGAGCTGGTTTGGTGTTCTCTTTCATGAGGGATTCGCCCCTCTTAGAGAGGAAGATTCGGTGGAGGTCGGCCAGCAGTTGCACGCCGGTGCTGGTCGGCTCCCCCATGTCTCGCAGATCCGCAAGTGCCGCAAGTGCCGCATTGTCGCAGGTCAGAGGCCAGTGACCGCCCGCAAACGATGCGCACGCCAGCAATGCTTCCCAGCAGTCCGCCGCCCGGTCGGCAATCCCTTCCGGCATGTCCGGCCACGCGACTACGTATTGGGTTTCCGTCCCAGAGTTTTTGCTTGACCTGCAGTGCCCATTGCGCAAGACGGGCGCCGAGAAGCGCGGCTTTGGGTTCGTCCTCCCGAATGCGCCAGGGCTTGACCGTCTCGCCAGGAGGCGCGGGCGCTTCATTGACACCACCACGGCGCGGCTCATGATGGTGTCCGGAAGATCGTCCAAGCCAGCAAGACCCACCGCGCCGTAGGCGGGGAAATCTACAACCTCCACATTGCTGCCCTGCACCACGCACCGAGAAGACGTTCCGCTTCTGCGGTGTCCGGCATTGATCACGCCGCGAATGTCTTCATGATCTCCGGCTTTGGGGCCGAAGATGGTGTCTACCCTCATCAACCAGCAAGCTTCGCCTGTTCGGTCATCGTTTCCTCCCCTGCTGCTCAACCTATAAGTGGTTTCAGCGGGCGGCGGCATGGACCGCGTAAGTTCCTGTACGGCGTGAGTCGGCACCTAGCGCAGGCGCGGCTGAGAGTCCTTTCAGTCCGGGCCGCGCTTGCGAGCCTGGTGTTACAGAACAACTTTGGAAAGGCTCGCACAAATGAGTGCTCTTACGACTCCCCGAATCAACCCCGATCTCTTGCAGTCGCTTTTGCATCTGTCGCCGTACGGCGCGGAAGGCGGTTACGCCACTGAAGGCGACGTGCTGGTCAATACCACCGCTGACGGCGTAGACCTAAATGTCATCTGGGACGAAGTCGCGGCAGTGGTGAGGGCTTGGAACGCCGAACGTAGTGCTCTGACACGCCTTCTGACGTTCAACACGACTAATACCGCCGACGCCATCCCGCAAAGCAGGTCCAGCGATAGCTTCGAGGAAGCATCCGAGTTCGGTGAGCCCGAGTCCATCCGTCCGCCAGCTGATTACGCGCTCATGGGCTACACGTTCAAGGACTATGACAAAGCGTCACGCTGGACGTGGAAGTACCTGAGGGACTCTACGGCCGAGCAGGTTCGCGCCGTTGCCAACTATGCGTTGGAAGCCGACAACAAGCTGACCACCGGCACCATCTTGCAGCGCCTGTTTGATCCCGCGCAGACCTCAAACGAATGGGGCCACACGGTTTACGGTCTCTATAACGGTGATTCGATGGTTCCGCCCGCGTATCTGGGCAAGGATTTCACCACAGCTCATCAGCACTACCTGGTATCTGGTAGCGACACTATCGACTCCGGAGACCTGGAAACCGCCATCCGTCAGGTCACCGAGCACGGCTATGGGACCGAACCCAACTCAAAGCTTTTGGCGTTGATGAACCCGGCCCAGGCCGAAGTGGTGGCATCGTTCAAAGCTGGGGTGCAGAACGCGCCGGACATCATCGCCAAACACGACTACATTCCCAGCGCTGGCGCTCCCGCCTACTTCTCACCCGACGAGATCGTCGGCCAGGTGGCACCGGAGTCGTACAACGGCCTCAAGGTGCAAGGCTCCTACGGCCCGGTATGGGTGATCCAATCCGATTTCATCGCTGAGGACTACTTCGCCGTGGTCGCAACCTACGGAGCCAACAGCCCTGACAACGCCATCGGCTTTCGCGAGCACGTGCAGACCCAGTATCGAGGTCTGCGAAACATTCCCGGCCGCGTTCCTGGCTACCCGATCCAGGATGCATTTTCCAGCGCAGCTTTGGTGTGGGTGTGCGCCGTCGCGGCCAGGCTTGCGTGACGCAAATCAAGGCCAGCGGTAATTACACGGTCCCGGTGATCCCGAGATGACACCCTCAGATTGGTTGCAGGCCAACCTGTCCGCGGTGATCGTTGCCGTGGCGACGGCCAACGCTGTCCTAGCCGGCGTCGAGAACCGTACTGCTAGTACAACTGCGCTTCAGGAAGGTTCACAGGATGCCGGGAGTATCTGACTACAACCCCCGGCACGCGATGGACATGGACGCCCTTGACGCTGAGGCATCGGAATTTTCGTGGGGATCGGGCCTCGAGCCTAAGGAACTCAGAGCTGCTCCGCCGTCTGAAGGTGGCCGGTATCGCGGTACCGGTCCGCCGTGCGAGAAGCACATCAAGGTGTCCAACAGACCCCGTTAGAATTACTTGTCCGTTAGGGCCTCGGTTTCCCTTTATTTTCCAGCTGCTTTAGGTGGCGAAGCGAAATTTGGGTTCGCGGCCCAGGAATCTAGAATATCTATAACGAAGCGACGTAGTTCATCGTATTGGTGGATTAGCGCACTTTTAGTAAGATTAGCTTTATTTCTCAGGTTGCCGTGCGCGAGGTCGCTGCGCGTGCCGTAGGCTTTGTCAAAGTATTTCTTCGGTGCCAGGCCGTCATAGGTTCCAGGTAGGCGATCAGCAAGCTGAAGTCCATATCTACGGACAGAATTCATTTTGTTGTTCTGAAGAAGCTTTTTAACCTCTTCTTTCGTGTCTTCATCGAATTGCGCAAGGCCGTCAGCTATCGGCTTTAAAGCGTCAAGGAGCCCAGACAGATGAGCGTGTTCTTCTCGATACGGAATTAAGGCCTCGACAGCGGTGACTGTCAGAATGTATTTTGCCTCCGGATTCGGGTCACCCAATCCCGCATGGACCAAGTCCCAGGCAAGGCGTAGCTGCTCCGGCCACGGCGTACTATGCTGGTGCTGAGCCTTCGTGATCAGGTTCGGCAAATCGCCTAAGCCCGACAGGCCAACCGCTTCATACGCAAAGTAGACGAACCGTGGTTCGCGGGGGTGCACCGGAAAAACCAGCAATCCCACGCGGTCTCTATACGCGCGATCATCGTCACTTATGCCGACACTGTACCGAATATGTAGTGGTACATTGTCGAGTGGGTTCAAATTCTCTTCATCATCGTCACCGAAATCGCATGCTATCGCAAGCTGCGCAAATATCCAGGTAGCAATTTGACGCCATTTACGTCCCGCAATCAACGCTGTGTCAAAATCTGCGTAGGCGCTTCCCCATAAGGCAAGGCTAGTGCAATTTTTGATCGTCTTTGACCCTAAGGTGGATGTCAAGCAAACGTACTCTTGCGCATCGCTTAGGATGTACGTTCCGTCAGATACGTTAAAACGGCTGTTGCTTGTGATGTCGAAACGGTTGCGGAAGGCGTAGCTGCCCGCGGGCGCAGAATCCGCTAGTCCGACTGGAGATAAGACATACGCTTGGCCTTCGAACTGGGTGCCTCCCGTCACGGCGCGAGATTCTATTCCGGCAGGCTTAGATGCGTAAGGGGCTCCTGGGCAGCATCGCCGGTTGCAGCCGTACCAGCTCTAGGGCTTCCAGTACGGCCGGGTCGTCGGGCTCGTACCCCCTTCAGCACGAATTGCCTCGCGCCTACTTCGTCCGTGTTCGGGTAGACGCAGGATGCAAAGTCGGCTCCATGTCTAACTGGCCCAGCCCAAGGCGGGGCACTGTGAGGTTGTCAAGGTGCGGAAAACGCGCACCCTCACACCGAACGGTGAAAGGTGGACCGCGTTCTCGCGCGTGCCTCCCGAAGGGCCGTGACTTCAACGCCGGACTGTTTGCGTTCCGCTTGGCCGTGCTGCTCTCGTGGGCCGACTCAATCGGTCGCGCGCCGTTTTCCTGCGCCCTAGTGCCGTCGTCAGCGGCACGCCGAAACCATTACCCATAAGTAGCTATCTGTCACATCAATGCCGCTTTCAGCCCTTTAGAAGCCGTTAACGATAAGCGCGTGCCGTTTGCTGGCGTTGGACCTGGCTACGAAAGCCGCAACCCTCCGGCCTGCGGTAACTACGGGGCATGGTGCGGGTGTGACAGCTGTGATCGTTGCCAGGGGACGGGGTGCTTCGTTCTGCCCCTTTCAGCGGCTTGCCTTGCCTGCGTCGGCTTCAGTCGACGTGAGTCACCTGACTGCTGACACGATGCTGACGCTGACTGCCGGGCCATGCCGGGAAGGCCGGTTGTCGGTACTGCGCGGCAAATGCCCTGACTTGGACATTTGCCTTGGTGCCCCCCTGTTCAGAGTCGGTTGATGGGTGACATTTCTATGTCGGTTGATCGGTGACACTCTGGGTTGTGTTTTAGGCCGGTGCGTTGGTGCGCAGGGCCCGTTTGTTTCGTACCTCGCCGCGGCTGGTGCGTGCGGCGGTTTTGACCAGATTGTCGCCGACCCAAAACCGCAGCAGGTCCCCATCGACGTGGACATCGCAGCGGGCGCCGGCGTAGTGGCGCCCGATACAGACCTGCTGCCAGGACACGCACACGATGCCGTTGGAGCACACCCGCCGACTCACCTAGTCATCGCCACTGCGGTCGACGTGTCGGGCACACGAGTTCGACGGTGGTGATGCCGGCGCACCGGAGTGAAACCGTTGAGCCGGTGTGATCATCTTTTGGGGCTTGGTGCGGCCGGGTGGTGTTGTAGTCCTCGACCCACTCATCGAGTGCCTGCTGAGCGACCTTGAGGTTGGTGAAAGGCTCACGGCCGCTAAGGAACTCAGCGCGCAGACTGCGGTGAAACCGCTCGATTTTGCCGGTCGTGGTCGGGCTGCGCGGTTGGGTCAACAGATGTTCGATGCCGTGCTCGCGGCAGATCGCATCAAAGAGCACCTCGACCGGTGGATGACAAAACCGCCCGGTGAACACCTTGCCGTTATCGGTCAAGATCTGCTCAGGCACCCCGTAAGCGGCCAGCGCCGCTCGTAATCCGTCGCAGACCGCGCGGGTGCGCTCACGGGCCATCAGCTTGGCGCACACACACATCCGGGAATGATCATCGATGCCGGTCAGGGCTTTGGCGCTGGTGCCATCGGCCAGCGGGAACCCGCCGACGATGTCGAGCTGCCACAACTCCATCGGCGCCCCGCGCTCCCAGCGCTTCCACTTGCGCGAGCGCCGATCCCGCACGCTCGGGTCGATCAGACCGGCCCGCACCAGCGCTCGATACACCGCCGACTCCGACGGCACCGGATGGACACCTCGCTTGGCCAACTCGAACACCAGCCGCCGCGGTCCCCAATACGGCCGCGACCGCCGCAACTCCAACACCGCCGCCTCCACTATCGCCGGCATCTGATGCGGACAACTCACCGGCCGATGCGACCGATCCACCAGCCCCTCCAGGCCCGCGGCTTCATACCGGGCCAGCCATCGGTGCAGCGTCTGACGCGCCACCCCGAACTTCTCTGCGGCCTGCGACACCGACAATCCGTCACTGATTACCGCCATCACGGCCTGATACCGCTGCTCAGCCACACTTAACTCCCTCATCTAGGGAGTGTCACCGATCAGCCGAAACAACTGTCACGCATCAGCCGAAACACTGACACGCATCAACCGAAGGCGAAATGTCACGCATCAGCCGACGTCATACATTATACGTCTGGTGCCCCCACTAGGACTCGAACCTAGGACCTGCGGATTAAAAGTCCGTAGCTCTACCAACTGAGCTATAGGGGCCGCGGAGTTTCAGGATACTTGGACCCAAAACCGGGCTCGTTTGAGGATTGGGCCCACGGTGACCTAAGCTGACGTGGCTCCCAACGAAACCACGTTGCGAGTACCCCGGAGAGATTCGGTTCTGGCCCCCTTCGTCTAGCGGCCTAGGACGCCGCCCTTTCAAGGCGGTAGCGCGGGTTCGAATCCCGTAGGGGGTACGCAACGCGGCGACGCGGAGCAGCAGCAAGGCCCTGTGGCGCAGTTGGTTAGCGCGCCGCCCTGTCACGGCGGAGGTCGCGGGTTCGAGTCCCGTCAGGGTCGCCAGCGCGGCGAGGCACTCGCTGCCTTCCGGCCAGGTAGCTCAGTCGGTACGAGCGTCCGCCTGAAAAGCGGAAGGTCGGCGGTTCGATCCCGCCCCTGGCCACCAAGTATCTGTGCATTTCAGCGCCCCTTTTCGCTCTGTCTACGAACTCGTCATCACCGATTCGGACTCGGCGATGGGGCCAATATGGGGCCAAAAACGAGGTGCCGTCGCTGCCAACTCTGTATCGGATCCGTCCCCCTCGACTCTCCGCTGTCTTCGAGCGGAGCCCTACGCGACATGCGCGTGGCCAGTGGCGATTGCACTAGCACCTGCGAGGCACAATTGCGTCGTGCCCGTTCGCTGGTCAGTCGTGGCTGCCGACGACTGGGCTGTCGCTGGCCTCGAGAGCCAGGGCCAGCATCCGCACGACTGGCTCAAACATCCGTCGAGAGAGCGTACCTGGCTGTTCAAACCCGCACGGCCAGAGCGCGATCGTTCCCTCGGGGAAGACACTGTGGAGAAGCTCGGAAGCGAGATGGCTCGGCTGGTCGGAGTGCCGGCGGCCACGGTCGAACTAGCCACTCGGGGCGGGGTGCGTGGCGCATTGGTTGAAGACGTGCGATTGCCAGAGTGGGAATTGCAGGCAGGGCAGGCGCTAATGCCAGAGGTGGTTATCGATTACGACCCGACTGATCCTGAAGCGCGCGGATACAATGTCGGCTCTATCAGGCAGGCACTCACACGGTTTGGATCACCGCCAGGCTCATCGATGCCTACGTCGTTTCGGGCTTTCGATGCGTTCGCAGGATATCTCCTGTTTGACGCGTTGATCGCGCATGGAGATCGCCACGACCGCAACTGGGCCGTCCTTGTGCCGCCGCCGGACGTATCCGAGCCCTCTTTCGACCACGCAGCTAGCCTCGGCTTTACGTTGAGCGACGAACTGCGCGCCGAGCACTTACGCGACGGAACAGTGATGAAATGGGCAGAACGTGGGCACGCGAGCCGATTTGAGCATCGCAAGGGCACGCGTTGGCAGACACTCGTGGACCTGGCAGGCGACGCCATCAGACTCTGTGGACCGAGCACCCGCGAGTACTGGCGTGAACGGATACTGTCGCTTGAACGGCGGACCGTTGAGGACCTATTTGCTTCTGCCCCAGGGATGACGGAGACTGCGCACCGTTTCACGGTCGAACTCGTCAAGATTAATCGAGAGAGGTTGCTCGATGTCCTCGCCTGAATTGCTGTTATCGCGGACGTCAATGGCCACGCGACGCTTCGCTGTCGCATGGCGGAACCGGCGGCGACGCTTAAATTACGCCGGTGGCCGTACTAGACCACGGTGCCAAAGGCTATCGATTCCAGTACCTAGTTGCGTCCAGCAGAGTGGTGTACGAGCCGGTGATGACCGGCGTGTCGTAGCCGGATGAATGAAGGTCATCGCGTGATTCTTCGAGGGACCGACCAAAGTCACTCGAGCAAAGGAATCAACGCGATGACCATTGCCCACGATATCGACCTGTCTGCCGTGCTGGCCGAACGACTCACCACCACGCACCCTGATGTGCTGCGCGAGTTGTTGGCCGCCTTCATTCACGCCCTGATGGGCGCCGAAGCCGACGCGGTGTGCGGTGCCGGCTACGGCCAGCGCAGCAGCGAGCGCACCAATTCCCGCAACGGGTATCGGCACCGCGAGTTTGACACCCGCGCAGGCACATTGGATCTGGCGATTCCCAAGCTAAGGCAAGGTTCGTACTTCCCGGACTGGCTGCTGGAACGGCGCAAACGCGCCGAGCGGGCCCTGACCACGGTGGTGGCTACCTGCTACCTGCTGGGCGTTTCGACGCGGCGGATGGACAAACTCGTCGAGACTCTGGGCATCACCAGCTTGTCGAAGTCCCAGGTCAGCGTGATGGCCAAAGAGCTCGACGCCGCGGTCGAGGCGTTCCGGACCCGGCCACTGGATGCAGGCCCGTACACGTTCATGGCTGCTGACGCCCTGGTGCTCAAGGTTCGCGAAGCAGGCCGGGTGGTCAACGTGCACGCGCTGATCGCCACCGGGGTCAACGCCGAGGGCTACCGCGAAATCCTGGGCATCGACGTCACCACCGCCGAGGACGGGGCCGGCTGGCTGACCTTCCTGCGGTCGCTGACCGCCCGCGGCCTATCAGGGGTCCGTCTGGTCACTTCCGACGCCCACGCCGGTCTGGTGGCCGCGATCGGCGCCACCCTGCCTGGGGCATCGTGGCAACGGTGTCGCACCCACTACGCCACCAACCTGATGGCCATCACTCCGAAATCATCGTGGCCGTGGGTACGCACACTACTGCATTCGGTCTTCGATCAACCTGACGCCGGTTCCGTTGCAGCCCAATATGACCGCATCATCGACGCACTGGCCGACAAGCTCCCCAAGGTCGCCGACCACCTCGAAGACGCCCGCGCCGACCTGCTCGCCTTCACCGCCTTCCCCAAACAAATTTGGCGGCAGATCTGGTCCAACAACCCACTATCCGTTAACCGGCTCTCCGGGGACACGGTTCGGGCTGCAGCGTGAGGTTCACGCACAAGCGCTGAGCACGGATGGATGCTGTCTGCATCTCGGTGGGGGAAGGCGGAGCGGCGATGCGGGTACTCAAGAGCGACAGCGGATATGTCCTGGAGGGCGACTGGGACGGGCAGGACGCGGTGAACGCGTTTCTCAACCATTTGGCGGGACGGGGGTTCAGCGCGGCCACGGTGCGGGCCTACGCATTCGACGTCGCCAATTTGAGCCGGTTCCTCGTCCAGCAAGCGGTCGGGCTCGCCGCGGTCGATGCGCCGTTGGTGTTCGACTGGATCGACTGGCAAGGCGTCCGCCGAACGGACCAGCCCACCGGCGGTCACCGCTCGTCGACCCCGCCGGCAGCTTCGACGGTGAACCGCCGGGTCGCGGCAGTGCGCGCGTTATTCGAGTATCTGGTGATGACCGGTGTCTGCACCGACAATCCGGTGCCGTCGCCGCGGCGGGGACAGGGGCTGCGCCAGTCGCAGCGGGGGTTGCTCGGTCATCTGGGTCCCGGGCGTGCACGCAGTGGCGGTAGGTTGGTGCGTCAGCCGCAGCGTCTTCCGGAATCGTTGTCCACCAACGATGTCGACGCGTTCCTGGCGACACTGGCAACGCACCGGGACCGGGCGATGGTGCTGGTGATGCTACTCGGAGGGCTGCGTTCGGCCGAGGCGCGTGGCCTGCTGCTCGCCGACGTCGATATGGGCCGGCGCCGGCTTCGGGTGATCGGCAAGGGCGGCAAGGAACGTCATGTCCCGGTCGATGCGGCGTTCTTCACCGAGCTCGCCGCCTACCTGCGATGGGAGCGGCCGCCGGGGTTGGCGACGCCGCAGTGCTTCGTAGTGCTGCGCGGCCCGACGACCGGTGCACCGGTCAGCGAGGCCGGGCTGCGCAGCCTGTTCCGTCGGCACCGGGAGACCTCTGGCGCCACAAGAGTCCGCCCGCACCGTTTACGGCATACCTACGGCACCGAATTGTCGGCGGCCGGAATCGATCTGCTGGCGTTGCGGGCGTTGATGGGGCATGTCTCGCCGGAGACCACGGCCCGCTACGTGCATTTGTCGATCGAGCAGCTCGCCGCCGAATACGGTGCTGCTCGTGCGACGTTGGCCGGAGCCCGGCAGTGACCACGGTGTTGGTCGGCCAACCCGTAGGCGCCGACGAGGTGGTGGCGGATTATCTCGACCACGTCGCCACCCTGGGTTTGAGCGGGCGGGCGGTACGCGACCGGATTCGGATCGCTCGCGACTTCACCGCACGCCACCGCGACCTGCACGCCTGGATGACGCTGCCGGCAGCCGAGCGGATCGCCGAGATACGGGACACCGGGGCGTGGCCGCTGATCTGTCACACGATCGGCACCGGCCGGTTACGGCTGGACGTCGAGCTGGCCGCGGTCAAACAGTTGACCGGGCTGGGCCGCGCAGTGGAGGACCGGGATCCGAGCGGATTCGCCGCGTTGCGGAATGCGGGAATTCGGTTGGGCTGGAGGAGTTCCTGGGTCGAGACGGTCCTCGGCGAATGTCTGGCGGTAGTGCTGGCACACCACGGCGGAATGGTCGCCGACCTGACCGGCGACGCGCTCGACGACTTCGACGCCGCGCTGTCACGTACCGTGGTGCCGCCATCGTCGCGGCGGGCATACAGGGGCGGCTGGCCAGCCTGCGGCAGCTGTTGTTCGAGACCGCGGTCATCGACACCGCGCCGAAACGCCGGCGGTGGGCCCGTAGCCTCGAGCAGCGCTTCACCGAGGTGGAGATGCCCGACCCGATCCGTCAGACGTTGCTGCGCTACATCGGCGTGCGCGCGGCGGTGCTGCGGCCCAAATCGGTCGAGTCGCTGATCAACGACCTGCTGCCCTTCGCCGAATACCTCACCGCTCACCATCCCGACGTCATCAGCCTGCGTGAACTCGACCGGAGCTGCATCGAGGGCTACCTGAAATGGAATCGCACCCGGGGCTGGCGTGGTCAGCGCGCCGCCGCGGGCGCCGGGCGCACCGTCTCGGCCGCGGTGGCCCAGTCGGCAGTGCTCAGTCTGCGCAACCTGCTCGACGACATCACCGCCTGGGGCTGGGCGCAGGCCCCACCACGGCGGTTGGTATTCGCCGCCGACGTCCCCAAACTCGACCAGCCGTTGCCACGCGCGCTAGCACCCGATGTGGACGCGGCAGTGATGAACGCCGTTGCCCACCTGCAGGATCCGTTCGCCCGCATCGGCCTGACCGTGCTGCGTGGTGCCGGCCTGCGGGCGGGGGAACTGCTCGACCTCGAACTGGGCAGCATCATCGACTACGGACCGGCCGGAACCTGGCTGAAGGTGCCACTGGGCAAGCTCGCCACCGAACGCATGGTCCCGCTCTCCGCCGCGACCCTCGCCGCGCTCGACGAGTGGGTCGCCCTCCGCGGCACGCACCGGCCGCTGCCGCACCCACGCACCGGCGTGCTCACCGACTTTCTGTTCACCCGGCACGGACGCCGCCTGGGCTACACCCGGCTGCGCAACGGGCTGCTCACCGCCGCTGAATCCGCCGGGTTGCACCGTCCCGACGGCGGCGTCCTGATGGTCACTCCACATCAGTTGCGCCACACCTGGGCCACCGAACTCGCCAACGCCGGGATGAGTCTGCAGGCCTTGATGTCCTTACTCGGGCACGTCACTCCACAAATGACGATCCGCTACGCCACCCTGGCCTCGCCCACCCTGCGCGCGGCCTACGACGAAGCGATGGGCAAGATGCGCCGCCAGTTCACCCTCACCCCGGTCGGCAAACCGATCCTGCCCGACAAGGTCGGCTGGCTGCACAGTGAAATGCTGAAAACCCGCGTTGCACACGGATACTGCGCTCGCCACGAATCCGCGGGCGCGTGCCCTTATGCCAACATCTGCGAAACCTGCGACAACTACGTCACCGCCCCCGAATTCCGCGACACGCTCACCGACCAACTCGCCGACGTCCAGGCCCTCAGAACCGACGCCGAGTGCCGCGGCTGGACCGACGAAGCCGCCCGCCACGACCGCGTCGCCCACGCCCTTACCGACCACCTCCAGCGCCTCGATCGATGAACATCCCACCCCGACGGGTTGACCCGCCCCCGAGGGCCGGATAAAAGAACGACTCAACAAGGAAATCCGCCGGCGCACCGACGTCGTCGGAATCTTCCCCGACCGCAACGCCCTAATCCGCCTCGTCGGCGCGGTGCTGGCCGAACAACACGACGAATGGGCCGAATCCCGCCGCTACCTCGGCCTCGACGTCCTCAGCAAATCCCGCGCCGACCACACGCCATCAACAGAACAGGAGGACACCCCGGCGGCACTGACCGCCTAAACCACCAAGTCGAAGAATCACACGACGACGTCGTACACCACGTCCCTGGACTTGACCCCAACCCCGTCTCCCGCCGTTGGTACTGGCCGGCAGGTCATACCGAGATCATGAGGCATAGTTTTCGATTCCCGCTACCAGCAGTGCGACATTCGATCGGAAATGCACCGTCGAGTGCGGTCAGGGGGTCGAATCTGCGAGACCGGCTTTAGGAGAGCGGTCAAGCCCTTCTGGTTGAGGTCCAGAAGGGGTGTCTGAGCTGGTCATATAGCGCCATCGCACACCAAGCGAAACCACCGCGTGCCGACCAGTGCAGATAGCGGGTTTCAGGCTGCTGTGGTACGGGTCTCGTTGGCATAAGTGTGTCGTAGCGCGTGAACGAGCGCACCCGACCGTTTCCCGGATCGGACAGGTGGTTGTGGTGAGTGGTGCGGATCGGTGCGGATGTGTTGCATTGGTAGGCAGTCGATTTGGCGACAAAGGGTGCGGACAAATGGGGACACAGATGATGTTGGTCAGGATGGTAGAGCACGACGATGGGTGCGTCCTATGGTTCCCACGTGGTGAACATCAATTCGAAATCGGCAGCGCGCAAGCGTGTCCGGGAGGCGCAGAACAAGGCCAACGAGGCACGTCTGGAGCGTGAGCGTCAAAATGTCGATGACGCTGCGTCGTTCCTCGTCGAGCTTGGGCGGCTGGCCGCCGTCGACGAGTGGGAGCGCAACCGTATCCTCGAGATACACGCAGAGGGAGAGCGGCGCCGTCACGAACACCGCCAGGCCGGCGCGACAGCGTTGGCCCGGATGCAAGGCCGCGGTGAAAGCCTCACTGCGATCGCTGAACTGGCGGGAGTCAAAGTCGGTGAGGTAGCACACATCTCGGCTGGGCTCAATCCGGGACGTGTGTCGCCAAGTGACTCATCCTGTGCATCAACGGGTTTCGGATCGCGGAGCGCATGACCCGATTTGACTCTGCGGGCGGACTCGCCGGTCTCGGCTCCGACGACCAGCACCGCATCGCTGATACCGCGCACAATGTCCCCACCAAGGACCTCGACGAGGTATTGCGGTGTATTGCCGCCAATCGGGCAGCTGATGCGACGCCGGGGCGCCAGCCCAACCGCTTCGGCAATTCTCGACGCGGGATTGTCACGCGGAATCATCAGAATGCCCGGTGTCGCCACCGTATCGATCCGATGCCCGATCGCAGCGCCCGCGTCTTGCAATGCTCGACGCGCGGCTTCGCAAGCCAAATCGATGGGATCGACGACGCTGTCGCCGCGGTGCGTGATCTCACCGACCGCGACGACAACGGGAGTGCGGGGCGGAATCGCCAACGGTCAGGTCACGTTCATCGTCGGCACCTTTGTTGCGACATATTTGCGATATTGTCACATAAGTAGCCATGCGACAACCGGTTGGGTCGTTAATTCACGATCGGTCCGAGGCTGCATACTTGCTTCGTGACGAAGAAATCGTTGCGCTGGGGCACGGCACCTCCCACGACCCGCGACGTCGCCCGAGACCTCCTGCTCGATGCCGCCGAAGCGTGCCTGGAGGGCAAGGGGCTGCCGGGCACCACCATGGAGGACATCGCCAGACAGGCGGGGGTGTCGCGCGCCACGGTGTACCGCTACTTTCCAAGTCGTGAATCCGTCGTTTCCGGTGTCATCCTGCGTGCGGCCGAACGCTACCTAGACCGCATGCGTCGACGGATCGCAGTACATCGCGATTTGGGCACGGCAATACTCGATTTCGTCGAGGTCACGGTACGCGCCGCTCATCGCGAGCCGACAATCGGATTGCTGTTCGGCAGTGACGAGGAACTCGCCGGCGTGGGGTTGGCCAAGGGAACGTCGGTGGCTTTGTTTGAACTCGTGGCCGAGTTCCTTCGACCTGTCTTCGCTGCGCACTGGGACCAACTCGAGCCCGGGGTGTCGGTCGACGATGCCGCCGAATGGATCCTGCGAACCGTCCTCAGCCTGCTGTCGGTCCGCGGCCCCAGACACCGCAGCCCCGAAGGCCTCGATGCCTTTTTACGCCGATTCCTGCTTCCAGCTCTGCTCACCAACACCCAGCCTTGCGTCGATGCAACAAGTGCAGAGTAGTGTCTCAAACCATCGCATCGATATCCGTGGATGAGAAGGGGCGCTAACCATGGAGTTCGCGCAGTTCAATCAGCAGATCGCCAAGGAATTGCAGAACGCGGCGGCAACCACGGGAGGACTCTCCAAATACCTGGATTTTCGCCACACCGAGTTCGCCGCCGGGCGGCTGGTTGTGCAGATGGATGCTCGGGACGACCTTTTGACTCCGTTCGGCAATCTGCACGGCGGATGCCTGTCAGCAATGGTCGACCACTGCTTGGGCGTGGTGTTTTACCCGGTGATCCCCGCTGGATCGTGGGTCGCCACAACCGAATTCAAGCTGAACTTGCTGCAGCCCGTGTCAAGCGGAGTATGCGTCGCCGTCACCGAGATCATCGCGCTGGGCAAGCGCAGCGGTGTCGCCAGAATCGACATCACCAACGACGGGCGCGCGGTATGTGCCGCCCAAGGAACAGTGACCGTCGTTAGCCCTAGGGGGAATTCCTCGTGATGAAAAGGACCGATGGTATTGTCGTCCGACTTCACAACGGCGAGCGCACCCGATGACCGTTACGCTCGAGCGATTCCGCACCACAGACGGCGTCACCCTCACGGCGGATTGCTACCGGCACGACGCTGCCCGCGCCGTTGTGCTGCTCCTGCACGGCGGTGGTCAAAACCGACACGCCTGGGCGACCACAGCGCGCCGCTTGCACGCTCGTGGGTACACGGTCGTCGCGTATGACGCCCGAGGTCACGGCGACAGCGCGTGGGACCCTACCGGAAGATACGACCTCGGACGGCTAGCGTCCGATCTGCTGGCCGTGCGTGAACACGCGAGCACCGACCGCCCGCCGGCCGTCGTCGGCGCATCCTTGGGCGGCATGACCGTCCTGGGCACGCACTTGCTGGCGCCCGCCGACCTGTGGGGAGCCGTCGTCCTGGTCGACATCACTCCGCGAATGGAGTTTCACGGAGCACGCCGCGTCGTGTCGTTCATGGCCGCCCATCCTGACGGGTTCAGCACGCTCGACGACGCCGCGGACGTCATTGCCGAATACAACAGACATCGCACTCGGCCCAAGAACCCGGACGGACTCCGTAAAGTCTTGCGGCAACGCGACGATGGTCGGTGGATCTGGCGATGGGATCCGGCCTTCATCACTTCCAACTTCCAGTTTCTGCAAGGTGACCCCGCGACTGGTGCCGAAAAGTTCGACGCGATCAGCGAACTGCTTGTTGAAGGGGCCCGCCGCGTGCAGGCACCCACTCTTCTGGTGCGCGGCGTCCTTTCAGATGTGACATCGCAGCAGTCGGTCGACGAATTCCTCAAGGTCGTACCGCACGCCCAAGCGGTGGACGTCTCCGGCACCGGCCACATGGTCGCAGGCGACGACAACGATGCCTTCACCGCAGCCGTCGCCGGATTTCTCGACCGCACGATAAGCACTTCAGCGTGAAAAGCTCTGGGCTATCTGGCGCAGCCCGGGCTGGCCGCGCCAAAATCATGGCCGAGCTCGGCATCAAGGGGATCAGTCCGCGGAGGTTTAAGACCACCACGGTGGTCGATCCGGCCTCGTTTCCGCCGGATCTGATCGGCCAGCGCTTTGATAAGGGCCGACTCGACGCGGTGTGGTCCTCGGATATCGAGCGCCGTGAGGCGCTGTTCAACCGAACGGAGGTGAGAGACCACCGTCGCCGAGCCATCGCAGTGGCCCGGTAGAAGCTGGGGGCAGCCTGATCTAAAGAGACTTTGGTGAGGGTGGGAAGCAGCCCCGACAACGCCGGGACGGCCTGGTACTGCCAGACGGGTCGGGTCCGGCTAGCGAGACGGGAAGGTGTACGCGAGGAACCAGCGGCTGAACGCCTCTTAAGAGAAGACCACCAGCTCCAACCTGGCGGATGCGGGCTGGGCAGCGACGCGCACCCGCCCTGAGGGCGGGGAACTCGTGGGCCGGTTGATGTCGCCGGTTCGGGAGGTCACGGTGAAGGACTGCGGCGTAGCCGTGACGAGGTCGCAGGGGCATAGCTGGACACCTCACCCGTCAAACGGTTGACAGTGAACACGGGAACCACCGCGCCGGTCCCCGGTCAGATCCGGCAGCCAGCCGGGCTGGAGGGGTAGGCAGTCGTCGGCTGATGCCGGTGTGGTGGGGCGGAGGAGCCGTAGTAGTCCGAGGCCGGGAAAGCCGGTCGCATGGCAAAGGGCTCCAGCGGGTTCGCGGCGAGTACGCAGACTGTGGAGGTCACTTGTGAATACGAGTGCTTTGTGGCCCGACCCGGACACGGCCGAGCTGCGGGTACGCAGGATGCAACGCAAACTGCACCATTGGGCGGTTGATGAAAGCGACCGCTGTTTCGATGATTTGTACAACCTCGTTTATGACCCCGCATTCCTCACCCTCGCGTGGGAGCGGGTGCGGACGAACAAGGGTGCGCGCTCAGCCGGTGCCGATGGGACCGCACCGCGGTCTGTCGGTGCGGCAGAGGCGGTCGGACTGCTTCAGCGGCTCCGCGAGGAACTCAAGGAGCGGATATTCCGGCCGGATCCGGTGCGGGAGGTGATGATCCCGAAGGCGAACGGCAAGCTCCGCCGCCTGGGTATCGCGACCGTCGCCGACCGGGTCGTGCAAGCTTCGCTGAAGCTGGTGCTGGAGCCCATTTTCGAGGCGGACTTTCATCCGTGCGCATATGGGTTCCGGCCGGGCAGGCGAGCCCAGGACGCCATCGCTGAGATCCATCACCTCGCCAGCGGCTCACGGGCCTATCACTGGGTTTTCGAGGGAGACATCACGGCGTGCTTCGATGAAATCTCGCATTCGGCCCTTATGGGCCGGGTGCGGCGACGTGTCGGGGACAAACGCGTTCTGGCCCTGGTGAAGTCGTTCCTCAAAGCCGGGATTCTCTCGAAAGATCTCGGCTACCGGGACACCATCACCGGCACTCCGCAAGGCGGAATCCTCTCACCACTGCTCAGCAATGTCGCCCTGTCCGTTCTCGACGAGCACTTCGCCGCGAAGTGGAAGGCGCTCGGCCCGGAATGGACACGTGCCAAGCATCGACGCGCCGGAGTTCCGACCATGAAAATCGTCCGCTACGCAGACGATTTCTGTGTCATGGTCCACGGCACTCGCGCTGATGCCGAAGCGCTTTGGGACGAGATCGCAGCAGTGCTCGCGCCGATGGGCCTGCGCCTGTCGGTCGAGAAGAGCAGGATCTGCCACGTCGACGAGGGGTTCGAGTTCCTCGGCTTCCGCATCCAACGGCAGATCAAAAGGGGCACGACCAAGCACTACGTCTACACCTGGCCGTCGAAGAAGGCACTTATGTCCATCACCGACAAAGTCAGGAATCTGACGCGGCGACACAAACATCGAACGCTCGCTGATCTGCTGCGCCAACTCAACCCCGTCCTGCGGGGATGGTGCAATTACTTCCAGCACGGGGTGTCCAAACGCACCTTCGACTACCTCGACCACTTCACATGGTGGCGGGTGGTGACTTGGATGCGCAAACGGCACCACGGGCTGGCGTGGGGCGTCTTCCATCGACGGTTCCTGCCCAATTGGCAAATCCGCGAAGGCAAGACGGCGATGTTTCGGCCGCAGAAGGTAGAGGTCACCCGATACCGCTACCGGGGCACGAAAATCATCACCCCTTGGACAGCGAGGCCGACGGACATCACTGCACCAGTGGCCTGAATCCGTGGAGAGCCCGTTGCGGAGAAATTCGCTCGGCGGGTTCGGAGGGCGGGCCGGGGAAACGGATCGGTAGAAATGCCGACACCGCGCCCCGGTCCGACCCCTACACCTATCTGGGCTGCGGGGAGGGCGACATGTTCTTGTGCGCGATCCGCGACGAGCACTCGCGGCGGGCACTGGGTTGGGCTGTGGATGATCACATGCGCACCGAGTTGGTCACCGTGGCCGTGCAGCGGGGGGTGTTCGCGCGCGGTGGGCGCTGCGCGGGTAATGCTGGGACAACGTCGGCGCCGAGTCGCTGTGGTCGAGTTTCAAACAGGAATGCTACTACCGGCACACCCTACGCGACCAAAGCGGAATTGATTGCAGGAGTTGACAATTGGATGAACTTCTACAATAATCAACCAAGGCATTAAGCGATCGGGACGCGCTCACCTATCGACTACGAGCGGACGCTGAACCCTGTCGCGGAAGCAAGTTATCCGTGTCCATTTTTTCAGGGGAACCCCAGACTTCGATCGCGACGTTGGCATCAGCTCGAAGCGTGGCGGTCGCCAAGCCGATGTCGCGAGTTCCACCGGATGATGACAGTGCCATGGTGAGAAGTAGCGGAACCCGGACAGCCAAACCGGCGAAGTGCATTGTTGTCGGCGTGGTCCTCGATAGCCCCGACGGAACACTTGTGCAAGACGCATATCCTGCTCACCATGCCAACAGAGTCCGTTCGCCTCTCGTTTCGCCGGCATATGCGTGAGCAAGTCTTGAGGGCTGCCCGGACCCTCACTATCGAGAAGGGCTGGGATCGCGTTCGCATGGGTGAAGTCGCAGAGCTTGTCGGCGTGTCCCGCCCGACGCTCTACAAGGAGTTCACCGATAAGCAGGGACTGGGCGACGCGCTGGTTGTGGCCGAAGGCGAACGCTTCTTGAATGGCATTCACGCAGTTTTGGCACAACACGCCGGAGACGTCGGCGGGGGCATCACCGCTGCGGTGTCGTACACACTGAAGGAAGCGGAAGCGAGCCCGCTCTTGAAGGCGGTGCTGACATCGAACCGGCCTACGGACAGGACGGTCGCTGAGTCAACCGGTATGTTGCCGCTCCTGCCGACCTCTGCGTCGCTACTGGAGCTGTCCTCGGCAGCCCTCGTGACCTGGTTCAACGAGCACTTTTCAGGCCTGGACGCCAATGACGTCAATGATGTCGCCGATGCACTGGTAAGGCTGACGGTGAGTCACGTCGTGCTTCCGACCGCCGACGCCGAGACGACCGGGGAGCGCATCTCGCGGATCGCACTTCGCTATTTGGGCGTTCATTCCTCCGCAGGCGAGGCGCGTTAACACTAAGGATTTTATGTTCAAATGTTGACTCTGAAGGAATAATTGTAAACACTTGGAGTGGGGCCGCACGAACCTTAGGAGATTCTCATGATTGCCAGCACGACGTCCGCACTGAAAACGTCGGCGGAGCGGCGTTCAGCACGTCCATATGATTCTGCCGACTTGTCCTCGACTGCATTTTGGGCCGGCACCGCCGCCGACCGGGAGAAGACATACGCCGAACTGCGCAAACGTGCTCCCATCAGCTGGCACCCGCGAGTCGAGCACACCATGATCGACGACGGGAACGACCGGGGCTTTTGGGCTGTGGTTACGCATCCGTTGCTTGTCGAGGCGACCCGGCGACACGACGATTTCCTGTCAGGTCAGGGCATTGTCATGGAGTCGATCCCGCAGGAATTGCTCGACACCGCTCAAGGCTTCATTGCGATGGATCCGCCGCGTCATACCAAGATTCGACGATTGCTGGCATCCGCATTCACGCCGAAGCAGATGCGACTGATCCACCATCAGATCGAGGCCAACGCGAAGCGCGTCGTCGACGACCTGGCTCCACAGGGCAAGGCCGACTTCGTCGACGAATGCGCGGCGTTGCTGCCGATGCACAACATCTTCGACATGATGGGCGTGCCGGACTCGATGCGCCGCGACATCGCGTGGGAATCACGGTATGCCGGTGGGTGGAGCGACCCCGAGGTGATGGGCGACGACCCAGTCATACCTCGCCTTTTCCAAGCGATGGGATTCCTAGGCGACGGCGCCCGCGAAATCATCGCTGCACGTCGCCGGCAGCCCGAAGACGACCTCATGACGAACCTCGTTCAGGCTGAAGTGGACGGTGAAAAACTCACCGAAGATGAGATCGTCTCGTTTTTCATACTTCTCACGATCGCTGGGAACGACACCACGCGCCAAAGCACCAGTCATGCGATGAAAGCCTTGACCGACTTTCCCGATCAACGAGCGTGGCTGATGGAGGATTTCGACGGACGAATCAAAGGAGCGGTCGAAGAGTTCGTCCGGTGGGCCACCCCGATCATGACCTTCCGCCGAACGGCAGCTCGCGACTGCGACCTGGGCGGACAACAGATCACCGAAGGTGACAAGGTCGTACTTTTTTACAGCTCGGCCAACTGGGACACCACAGTGTTCACCAACCCGGAAAAGTTCGATTTGTCACGGGACCCCAACCCGCACGTGAGCTTCGGAGGTGGAGGTATCCACCACTGCTTGGGCAATCAGCTGGCGCGGCAGCAACTCGCCGCGCTCTTCCGGGAATTGCTGCACCGCCTGCCTGATATTGAAGTCTGCGGGCCACCCAGCTATACCGTTAGCACTTTCTTCCACGGGGTGAATCATCTTCCCGTCCGCTTCACCCCGACTACGTGAGGCAGCGTGGCATGAAAATCACAGTCGACCGCGATCGATGCTCGTCAATCGGGATGTGTGAAGGCCTGGCTCCCGACTTCTTCGAGGTCAGTAACGATGGGAAACTCCACATCCTGAATCCTGGGCCACCCGAATGTCACAGGGCACTGATCGAAGATGCCGTGGCGAGTTGCCCCACAGGCGCGCTCGCGTTGCACGATTGACAGACTGGCAGCAGCGAGATCCGGTGCAGCTGTTCGGCACTGGCTTCCGGCCGGTCCACGATGACTGCTCCTCGTCCAACGGGCTCGCCGACATCGCTCAGGAGCACAACACAACGCAATGGAGCCGCAGTAGTGAGTACCTTTGGACTCTCTGTCCTAGCCCCTGACCTTGCCGCGATGAAGGTCACCGCCACCGCGGCCGACCAGGCCGGGTTCGACGCGGTGTGGGCATCGGAGTTCTATACCCGGTCGGGATCCATCTCGATGGCGGCAATGGCCACCTCGACTGACAGGTGTCGCATCGGGTCGTCGATTCTCTACGGCGTCGGACGCAGCCCGCTGGTCTTGGCGACCGAGGCGCGCGATCTCGACGAACTGTCCGGCGGTCGCATCGTGCTCGGCATCGGCAACGGCACCAAACGGATGATGAGCAACTGGCACAGCGTCGCCGATACCAGCGCCCCCGCCCTGCGCGTCGAGGAACTCGTACCCCTTATTCGGCGCATCTGGAACCTGCACGAGGGACCAGTCCGCCACGAAGGCCGCTTCTACCAGATGAATCTCATCCCCAGCGGCCCGGTAGACCCGCCTGCGCGCGATATTCCGATCATCACCGCCGCGGTGCGCCCGCGGATGTGCGAAGCCGCCGGCCGGGTCGCTGACGGGCTGGCCGGGCATCCGCTCTTCACGACCGCCTACGTGGAGGAAGTCGTGCGGCCCGCGGTGGCCAAGGGCGCCGCACGCACCGGGCGCGATCCCGACGACGTCGAGATTGTGTCAATGGTCATGTGCTCCATCCACGACGACCCGGAAATCGCCCGTCGCGAGGTCGCGCAACAGATCGCGTTCTACGCATCAGTCAGAACCTACCAACCGCTGCTCGACTTCTGCGGATTCGCCAAACAGGGTGCCGTTATCCGAGAAGCCTTCGCACGCGGTGACTTTGCGGCCATGTTCGACGCGGTGACGGACGACATGATCGACGTGATGGGCGTCGCTGGCACCGCCAGCGAGGTGCGCGCCGGGCTGCGCCGCTACGAGGGGGTACTCGACCACATCATGCTCTACCCGCCGTCGGTGGGTATCGCACCTGAGCGGGTCGGCCAAAACCTCGGTGAGATGATCAAGCACTGCGCCCCCGGCCAGTAACATCCCGGTTCATGTAGGTGCGCCAGCGTCTGTGTCGACGACAACCCGCGGCGGTGAATGAGTCTCCCGTCTAATTCGAAATGACCGGTTCATCGACGGTGTGCTCCTGCCGGTACCGTAGGGATCGCCTTCGACGACGAGTTCGTAAGCCACCTAGTGCCAGTGCTTCTCTGCTCGCGCTCACCGTTGATGCTAGACGCGGCTCCCGATTCGCTGGGCGCCATCGGAGTCGAAGAGTTCTTTGGCCCAGCGTTCGAGGACTTCGGTGCTGTCCCAGTCGTCGGGGTGGAAGCCGGCGCGGGTGTAGGAACGGAAGCGCTGCACCGCGTCCGGGCTGAACAGTGGGGAACGACGGAAGGCTCGAAGGCTGCGCAGTAAGCGCAGTGGGTTGTAGGCTGCGCGGTCACCCGCCAGAGAGCGAGTGGTCTGGATGACCAACTCGGTGAACAAGATGACTGTGGCAATCCGCATTCCCCAGACCCTGGTGCGTTCGGTTCCACCGACCGTCTCGAAGACGTCGAAAGCGACGGCCTTGTGCTCGGATTCTTCTAAAGCGTGCCAGAGCAGAATCGGCCGGACCTCGGTGTCGCCGATCAGCTCTTGTGCCTCGTCGCTGGTCAGAATGATTTCGGCGAACGTCGCCGTGTAGTGCTCAAGGGCAGCCGTCACGGCCAGGCGCATCTTCGGAGAGAATCGCTTCTCGAGCCGGTCAACCAACTTCTTGATGTGCCGATCGATCCCGTCGGTCGGATAGCCCATCGCTTGGAGCCGCTCGTTAAGCAGCCGATGCTGGTGCCGGTGGGTGGCCTCCTGCGCGATGAATCCCTTGACCGCCTCTTGGAGGTCGGGGTCGCTGACCTGGTCACGGTACTGGCGCACCGATCGGATGAAGAAGTCTTCGCCCTCGGGGAACGTTGCCGACAAGGTAGAGACAAAGTGGCTCATCACCAAGTCGCCGTCGACGAAGTGCTGGCGACTGGTCCCAGCAGGCATTGCGAAACGGACACGGCGAGCCTTTGGCAGCACCCTCTTTGCTGGCCGTGTGGGCGACTCACTGGTCATGTGCTACTCCCATCTCCAAGCGGACCTCAATAATCTGACTTTATACCTAGTCAGATTTAGATGACAAACTGTGTCTATGCGTTCAGTCCGGGTGTATCGCGGAGTGTCTGCAGAGCAGCGCCATCAGCACCGGCGTACACGTCTCATCGACGCCGCTATCGAGCTGATCGGTACCCGAGGCGTGGCCGCCACCACCGTGACTGCCGTCTGCGCCGAGTCACGTGTCACCTCGCGTTACTTCTACCAGCATTTCTCCGACCGCGACGCGCTCTTGCGGGCCGTCTACCAGCAGCTCTATGCCACCTTCCAAGACGTAATAGTCCAAGCGATCCCAGACGCCGGCGCGCCACCCGACGTGTTGGCGTATGCCCCCATCCGCGCACTGGTCAACATGATCGAAGACGATCCTCGGCTGGCCCGCATTTTGTTCGTTGAATCCGCAACGGAGCCACTCCTTCGCGAGTTGCGGAGCCAATTGATGGCCGGTTTCGCCGACCTCGTGCTGCGCGAGGCCAGACTTCACCTGGATATCGCCGACTCTGCGGTGGGCGTCGCGCATCTGGCTTCAACCCTCGGTGTCGGAGGACTCTTCGAGGTTCTGCGCCGCTGGCTGGACGGCGAACTGGACTTCAGTACTGATGAACTCGTCCAACACTGCGCAGGTTTCCTGGGCAGCCTCGGCACCTACGTGCTGCTGCAGAACATAGGCGAGGCGCCGGTTCCTGAATCCGGGGCATCGGCAAACGCTCTATCGGCTCGCGGCCACGCCCGGCGATGCTGAGTGCGTGTCCGGTTTGACGCCCACGATCAGGACGGTAGCGTCCCGGGCACGTCATCGACGCTGAGCGCGTGCACCAGATAACGTTCAGCTAGGGTTTCGGCGAGCCGACTGGTGTGTTCGACGATCTCCTCCTGACTTACGTCGAGCAAGCCGGCATGCCAGGCGGTGATCAGCTCGACGAAGCCCCCAACCGCCACCAAGGTGTCCATGCGGAGCGCGGTTTCATCGGCATCCGGTCTCAGATGGGGCTTGCTCGCCGCGACCACGAGGTGCGTCGCCTCTTGCAGGGCAACAGCGCGCCGGTCTTGCAGCGGTGAGCTGCCCACGTGCTGGGTCAGCAAGATCTTTGCCCTGCCGGGATCTTGTGTGATGCGGTCGACCACCATAGAGATGGTCATGCGAATAGTCTCGAGGGGCGGCTGCCCGACGCGTTCTGCGAGGGTCGCGGAAACCTCACCGAGCATCTCGTTCCGTACCCCGTCCCAGGCGGCAACCAGCAACTCGTCGCGGGTCTTGAAGTCTTCATAGAAGTAGCGGTCGTTCAGGCTGGTCCGGGAGCAAACGCCCCTCATGGTGACTGCGGCCCAACCGCTTTCGCTCCAGATCTCGGTCGCGGCATCGATCAGACGCTGCCGACGTTCCGCGCGGCGTTCCGCGCCGGTACGCCCGCCCCATCGTTTCGCCTTCGTCCGCACATTTCCATCTTGACAAAGCAACGTAGGTCACACCAAACTGACGGCATGTGCCCACAATGGTGGCTGGTGCCACCAGTTGCTTTCGAGGCAGCGACGGAATCAACCGTCAGATCGCAGCAACGGCGGATACTCCGATGAGGCTGCTGCCGTTTGGGAATCCCCCCCGCCGGAGTGACCGTGCCGACGCGGTGATCACCGGTGCAGGCAGCGGCATTGGCCGCGCATTTGCCGTCGAGCTGGCGCGCCGGGGCGGCCGTGTGGTGTGCGCCGACATCGACGGCATTCGCGCCAAGGAGACAGCGGACCTGATCTCCAAGCTGGGCGGTCATGGCATCGGCGTTGTTTGCGACGTCTCAGACGAGCATCAGGTCCGGGATCTTGCCGATTCGGCCGAGAAGTGGTTCGGCGGCGCTCCCGGACTGGTGATCAACAATGCCGGAATTGGCGCTGGAGGCAACGTCGTCGGTGCGACATCCACGAGCGATTGGTCCGCGACGTTGTCGGTCAATCTGTGGGGAGTCATCCACGGCTGCGAAGTCTTTGTCCCGCGGCTCCGGGAACGTGGATTCGGAGGGCTCATCAACGTCGCGTCGGCGGCAAGCTTCGGTGCGGCCCCCCGCATGGCCGCCTACAACGTGAGCAAAGCGGGCGTACTCGCGCTGTCCGAAACCTTGGCAGCCGAGCTCAGCGGAACCGGCGTCACGGTGACCGTCCTATGCCCCACCTTCGTCAAAACAAATATCGTCGACAATCCACGCATCGAGGAATCGGCGGCCACGCTAGCCGCCAACTTGATGAAGTGGACCGGCGTATCACCAGAGTCGGTAGCACGAACCACCCTGGATGCGCACGACCGCGGCCAGCTATACGTCCTGCCGCAACTCGACGCCAAAATCCTCTGGCAGCTCAAGAGAACCATGCCGGGTACCTTCACCCACGCGATGGGACTCATCCAGCGAATAACGCGTTGACACAACCTAGGAGGAGACATGGCTTTCGAATACGGCGATATGCTGCAGACGATTAAAGACCGCCAGTGGGCGCTGGCCGACATCGACTGGGACGCACCGGGTGCCGAGTTGATCACCGACGAACAGCGCCCCAGCCTGAAACAGTTCATGTCAGACGTGGTATGGATCGAGCATGTCGGTGCCCGCGCTTTCGCGGCCATGGCCCCCAAGGCGCCGTTCGACGCGTTGGGTGAGATTTACAGGTATTTCCACGCCGAAGAGCAGCGGCACGCCAACGTGGAGCTCGCTCTCATGCATCGCTGGGGGATGCTCGAGGAGGGCGAGACTCCGGTGCCGAACAAGAACATCCGGCTGGTCATCGAATGGCTGGACCGATACGCCGAAGCACTTCCGTTGACGGTGATCGGTGCTGCCATACCGGCTTTAGAAACCGCTCTGGACGGAGCACTGTTGAAGTTTTTGGTGGACGAGGTGTCAGATCCCGTGTGCGGCGAAGTTTTCGCCAAGGTCAACAGCGACGAGTCTCGCCACCTGGCGGTGGGTTTTCAGGTGCTCAACGACCTGGGCGCCAGCCCAATGAGGATCCATGCGATTCAGACGGTGGGAGCTCTTATCGACCCGAGGGTACTTACCGGTGCGTTGCTTTACATCCCGCTGCTGACCCGGATGCTGATAAACCTGAACGCCTGGGGCCTGTCCGAGGAAAGGCTGTACAACGCAGTCACCCGCTACTCGAACGTCGGCGATCGCAGCGAGCACACCCGCCGTGTTCCCCCCTATCACATCCTCAAGGCCCATATGTCTGCCACGATCAAGCACTCCCAACCGCTGCACTTCATCTCGCAGCGCCTCGGTAGGGTGATCGACCACTTCCCCACGCAAGTGCTCGGCAAGACGCCGTCATGGACTGATGAGCTGACCTATGAACCGGTGGCCAGATGAGCGACACGACCAGTGTTCTGATCATCGGAGCCGGCTTTGCCGGACTTGGCACGGCGATCCAACTACTCAAGCGGGGTATCGACGATTTCGTCATCCTGGAGCGCGCGGGCGAGGTCGGAGGAACCTGGCGTGACAATAGCTATCCCGGTGCCGCCTGCGACATTCCGTCATTGTTGTATTCGTACTCCTTCGAACCAAATCCGGACTGGTCGCGTGCGTACTCGGGAAGCAGCGAGATACTCGCCTACATCAAGGCCATGGTCGACAAGCACGCGCTGGCGCGCTTCATCTGTTTCCACGTCAACGTGACCGGCCTGGCGTTCGACGAAGACAGCGGCACGTGGACCGTCGAAACGGATGGCGGGTCAAGCTACCGGTCGCGCACGGTGGTGATGGCAAGCGGCCCACTGGCCAATGCAAATTTTCCTGACATTCGCGGACTGCACAGCTACGCAGGCCACAAAATCCACAGCGCGCGCTGGGATCACGACTATGACATGAGCGACAAACGTGTTGCGGTAATCGGTACCGGGGCGAGCGCGGTGCAGATTGTTCCGGAATTGGTGAAGACGGCGCGATCAGTCAAAGTGTTTCAACGGACGCCCGGTTGGGTGCTTCCCCGGCCTGATTTTCCGCACCCCAGTGTTGCCAAGGCCGCGTTTGGTCGGCTACCGATTCTGCAGAGCGCCGCTCGCCAGGCATGGTTTTGGGCGCACGAAGTCATGGCCGTCGGCATGGTGTGGAACACCCCGGCCACTACCGCCATCGCCTGGGCGGCCAAGGCGAACCTTCGTCGCCAGGTGAAAGATTCGTGGATGCGGCGACAACTGACGCCCGACTTCCGGCCCGGCTGCAAGCGCATGCTGATGACCAGCGACTACTATCCGGCTCTCCGACAGAACAATTGCAAACTCATCACCTGGCCGATCGCGACCATCTCGCCCATCGGCATTCGCACCGCGGACGGCATCGAACACGAGGTGGATTGCATCGTATTCGCGACCGGCTTCGATGTGTGCAAGGCCGGCACACCGTTTCCCATCACCGGCGTGGACGGTCGAAAGCTTGCGGAGGAATGGTCTAACGGCGCCTACGCCTACAAGAGCGTCAGCGTCTCAGGCTATCCCAACCTCTTTTTCACCTTCGGGCCGAATTCCGGGCCAGGACACAACTCGGCCTTGGTCTACCTGGAAGCGGAGATCCGCTACATCGTCGACGCCATCGGCATAATCATCGAAGGCGGTATTCAGACCTTCGACGTCAAAGAGGACCGGCAGAACAGCTATCACGCCCAACTCCAGCGTCGGCTTGCCGGCACGACGTGGAACTCCGGATGCAAGAGCTGGTACCTCACCGAAGACGGCTATAACGGGACCATGTATCCCGGCTTCACCACCCAATTCGCCCGACAACTAGCGAGGGTCGAGCTCGACGATTACTCGATGAGTTCACAGCCCCCTCCCCGCAAGAAGCCCAGGCGGGCGCGGCCCGAGTTGGCCGCGGAGAGTTCGCACGGCGCAAGCAAAGGAGGACGGCAGCGCAACGACGATCGCGTGTCCGTCGACAAGCGCGAAGGTGTTCGTTTCTCGGCGCAAACCGCTTCACCCGAGGCAGCATCACCGCGGATGGTGGATCGTGCTTGAGCCGCGACTGGCTCCGGCTAGGCAGTCGGCGACAGGTGCCTGGCATCAGCCCCCAGATAAGCCAGAAGGACGGTATGGACCACAGCGATAAGCACCGCTTCGAAATCATCGTGATCGGTGCAGGATTCTCCGGGATCGGAATGGGGATAAAACTCCTGAAAGCCGGCTTTTCGGACTTTCTTATTGTCGATGAGGCAGACGACGTAGGCGGAACGTGGCATTGGAACACCTATCCGGGCATCGCCGTCGACATTCCGTCGTACAGCTACCAATTCTCCTTCGAAAAACGGTCGTCATGGTCGCGGACGTATGCGCACGGCAACGAGTTGAAGGACTACGCAAGACACTGCGCGCACAAGTACGGTCTTAGCCCACGAATCCGCTTCGCCGTCAAGGTGACTGAAGCTTGGTTCGATGAGGACGCGACCCTGTGGCGCTTGCACACGGCCGCAGGACAGGACCTATCCGCGCGCTTCGTGATCAACGCCTCGGGCGTCCTGACACGCCCCAAGCGGCCGGATATCTCCGGTGTCGATGATTTCGGCGGGATCACCATGCATACATCCCGCTGGGACCACAACGAAGACATCGCCGGCAAGAGGGTGGCTGTCATCGGAACGGGCGCGTCGGCAGTGCAGTTGATCCCGGCAATCGCGAAAGACGTCAAGGCGCTGACCGTGTTCCAGCGCACACCGATCTGGTGCCTGCCGAAACTGGACTTCCCGGTGCCGCGGCTGGCAAGAGGGTTCCTCAAATACGCTCCCGGCGGACAACTCGCGGCGCGCGCAGCGAGTCAAACCTTCGTCGAAGTCACGTTCCCTGTCGCCGCTCACTTCCACACCGCCATTCCCTTGGCGTCACTCATCGAGCGTGCCGCGTTGCGGTACATGCGCAGCCAGGTGACCGACCCCGCCGTCCGTCAAAAACTGACCCCCCGTTACGCGCTCGGGTGTAAGCGCCCAAGCTTTCACAACGAGTACCTGGCCACATTCAACCGAGACAACGTCCACCTCGAGACCAGTCCGATAAGCCACTTCGATGCCGCCGCCGTCCACACCGTCGACGGCCGATCGCACGAGATCGACGTCCTCATCCTCGCCACAGGCTTCAAAGTGATGGAACCGGAGAACATGCCGACCTATTCGCTCAGGGGGATCGGTGGACTCGATCAAGCCAAGTGGTGGGACGAGAATCGGCTCCAAGCGTACGAAGGCGTCAGCGTGCCCGGATTCCCCAACCACTTCTCCATCTTCGGACCCTATGGATACAACGGTTCCTCGTACTTCACGCTCATTGAAGCCCAGACCAGGCACATCGTGCGATGCCTTCACCATGCGCGGTCCCGGCACGCCAACTACGTCGAAATAACCCGGCAAGCCAACGACCGCTTCTTCGCCGAAATGCTCAAACGCCGCCACCGCCAAGTCTTTTGGCAACCCAGCTGCGCAACCGCCAATAGTTACTACTTCGACAAACACGGCGACGTACCGCTACGCCCGACGACCACCCTCGAATCTTTCTGGCGTAGTCGCACCTTCGACCTTGGTGACTATTCGTTCGAGCGGCGCACCACTGAAAAGGTACTTAGCTCATCGTGACAACCCTTTACTCGGAACAGCATCCGAGCACGGCAAGTTATCTCATCGCGACGTCGGCCCGCGGGATCCTGCGCCCACTGACGCAAGCACTACCGTCTAACCAGTACGGGCTCGCGGTAATGGACCGGGTGCTTCGGGCGGCGCTCATTGCGTCCCGCCCGCGGCGCGGATTGCGAGTTGAACAGGTCGACACCGTCTTTGCTGGCGATCGGGTGAGAGGCGACTGGATCGTTGCCCCGGACGTCGACCCGGACGGGCCGCCGATTCTCTATATCCACGGCGGCGCCTTTTCCATGTGCTCCCCGCAGACCCATCGTGGTCTGCTAGGCGAACTGTCTGCCGCGTCGCTCAGGCCGGTGTTCGCCGTCCGCTACCGCCTGGCTCCGCGATACCCGTATCCCGCGGCCGCCGACGACGCACTGAGGGCCTACCGGTGGTTGACCGGCTCTGAAGAATCGGCGTCAAACCGCACGGTGGCGATCGCGGGAGATTCGGCGGGCGGCCAACTCGCCGTCGCGACCTCGTTGGGCGCGCTCGCACATCGCTCCCCGCCGCCCGATGGCATGTTACTCATGTCCCCCGTCGTCGATCTGACGTGCCAGCTGGCGATGGCACGTGAAACTCGCCGCCGCGATCCTTTCGCATCGGCCCGGTCCGCAACGCGTGCGCTCAGCCTCTATGTAGGCGATGCCCACCCGACCGACCCCCGCGTCAATGTCCTCGCCGCAGATCTCACCGGCTTGCCGCCGACATTGATCCAGGTCGGTGGAAGGGAGATGCTGCTCGACGACTCCCGTCAACTCGCCGAGCGCATGCGCGCCGCAGGAGCATCCGTGCGGCTTCAGGTGTTTCGCGGCCAGATTCACGTGTTCCAAGCCCTGTTTCGACTCTTGCCCGAGGCGCGTCACGCTTTGCACCTCAGCGGAGCGTTTCTCACAGACAGGGCCGAAGACACGTTTCCTTGACGCACGGGCCGAACGCAGGCAGGCGGCTAGCGCGCAGCAACCGCTTTTGTCACGCCCCACCGCGAAGGACCCGTTTGACAAACAGGGCAATTATGTATAACTATTAACATTGGTGGCCCAACTGTAAACAGCTGGTCGATCCTCCATCCCACGACGACCACAGGCCGGGGAGCGACAATGGTTAACCCGCTACACGCACCCGTCGATAAAGCCCGGGAACGGTTATCTTCGGTCATCTTGATTCCCGCGCCGCAACGGGTGGACGACGGACTTCGCCGGTGGAGTCGGCGGTGGCCAGTGCGTGAACTAGCCGCGCCCCCGGCCGGAAGCGGACTGCGACCGGTTCTCGGTGATGCCGGGCTCCCCTTGGTCGGGCACACCCTCGACTACATCCGGTTTGGGTCCGACCTGGGCAGAGAGCGCTACGAACGGTTCGGATCTGTCTCGTGGATGGGAGCGTTCGGCACCAAAATGGCGGTCATCGCGGGCCCCCAAGCTACCCAGGAGGCGCTCACCACCAACGCAAAGGCGTTCTCGCAAGACGGCTGGGCCTTTCTCATCGACGCGTTCTTCCACCGCGGATTGATGCTGATGAGCTTTGACGAACACCTCATGCACCGGCGCATCATGCAGGAGGCCTTCACGCGGCCGCGACTGGCCGGCTACGTCACCCAAGTGACCCCTTGCGTCCGCGCAACCCTGCCCACGTGGCCGACCGGCCCGTCCGTCCGCATGTACCCGCTGTTGAAAAACCTGACCCTCGACATCGCCACCGATGTGTTCATGGGTGGCCGAGGCAAAGACAGCAGCGACGCCATTAACCAGGCGTTCGTCGCTACGGTACGCGCGGCCAGCTCACTCGTCCGCGCGCCGCTTCCCGGCACCCGCTATCGCGCCGGGATCCGCGGCCGACGGGTGCTCGAGGAATACTTCGCCCGGCACTTGCCGGCCGCCCGGGCCGGCAACAGCAATGACCTGTTCGCCGCGCTGTGCCATGCCAGCACCGAAGACGGACAACGTTTCAGTGACTCCGATGTCATCAACCACATGATTTTTCTGATGATGGCCGCTCACGACACATCGACCATCACCACCACCGCGGTAACTTATTACCTGGCAAAGCATCCAGAATGGCAAGATCGGGTTCGCGCCGAAAGCGATGCTCTCGGCGACCGATCACCCGAGATCGACGATTTGGAAGCGCTCAGGTCGCTCGATCTGGTGATCAAGGAATCCATGAGACTCGTGGCGCCGGTCCCGCTAGTCATGCGCAAAACAGTGCAAGACACCGCAATAGACGGCCACTACATTCCCCGCGACACGCTTGTGGCGATCACTCCCGCCGTCAACCATTTCGTCCGCGAAGTCTGGCATAACCCGGATCGCTTCGACCCCTTACGTTTCGACGACCCGCGCCGCGAGGACCAAGCTCACCGCTTCGCGTGGCTGCCCTTCGGCGGTGGCGCGCACAAATGCATCGGCATGCACTTCGGCACCCTCGAGGTCAAAGCGATCCTGCACCAGATGCTGCGCACGTTCACCTTCGGCCTCGACACCGACTACCGCATCCGCTGGGACAACACATCGCTGCCGATCCCGGTCGACGGGTTACCGATCACGCTGCGCCGCCGATGAAGACAGAATTTGCGCGGTTCCTCGCAGCCACCGAATTCCTCGACTGGAAACACGATGCCGTGCAGCAGTTCACCGAATCGGCGACACGCAACGCCACCGATTCCGTCGATAAGGCGTGCCGCATCTTCACCGCTGTCCGTGATTCGATCTGGTACGACCCGTATTCCGTCTCCGACGACCCGCGCCAGTACCGAGCCAGCGCGGTCGCCGTCGCCGAGCGCGCCTACTGTGTCCCCAAGGCGGTGCTCTTGACGGCTGCATGTCGCGCCGCGGGGATTCCGGCGCGGTTGGGTTTCGCCGACGTCCGCAACCATCTACAGACCGCGAGTCTCCGTGAACGGATGGGTGGTTCGGACGTTTTCGTCTACCACGGCTACAGTCAAATACTGCTGAATGGTCGGTGGGTCAAGGCCACACCGGCATTCAACCGCGAGTTATGCGCGCGCTTCCGCGTCGCTCCCATCGAATTCGACGGTCAGCGAGACGCCATGTTGCACGCCTACACAGGCGACGGCTCTCAACACCTGGAATACCTCCATGACCGTGGTGTTTTCGACGACCTTCCCCTCACGGAAATCATCGACGCGCTGCGCGACAATTACGGCGAACTCATCTACGAACCTCCTCCAGTGCCGGACTCATTCACCAACTAGCAGTTTGAAGGATTGTGCCTGTGCAAAGCACCATGCAGGATATCCCCTTGACCGTAGCCTCGATCGTCAGGCACGCGACATCCATCCACGCTGACAGCCAAGTCGTCACGCCGACCGGATCGGGCTACCGCACAACGACCTACGGTGCGCTCAAGCGACGAATCAGCCAGTTGGCCAACGCACTACGGAGTCTGGGCATAACTGACGATCAGCGCGTGGCCACCTTCCAATGGAGCAATCAGGAACACCTGGAAGCCTACTGTGCGGTGCCGTCGATGGGCGCGGTGCTTCACACCCTCAACCTTCGACTCACCGCAGAACAACTTGGCTACATTTCAGATCACGCCGACGACAAGGTCATCATCGCGGACGTCTCTGTGGCACCGCTTCTAGCGAAGGCACTGCCGACGATGTCGTCGGTGCACACCGTGATCGCAGCGGGCGACGGCGACCTGGAGCCGCTGCTGGCCAGCGGTAAAAACGTGCTGCGCTACGAGGACCTGCTTGCTGATCAAGACGGCGAATTCGACTGGCCAGAGCTCGATGAGAGGTCGGCCGCGGCGATGTGCTACACCAGCGGCACTACCGGAAACCCGAAAGGTGTTGTCTACAGTCATCGTTCCACCTATTTGCACTCGCTGACTGGCTGCACACCCAACGTGCTGTCCATCGGTGAAGAAGACCGCGTCTTGGCGATCGTCCCGATGTTTCACGCGAACGCATGGGGGCTGATCTATTCCGCGCTGATGTGTGGAGCCGACCTCGTGCTGCCCGACCGATACCTGCAGGCGGCACCGTTGGTTGCCATCATCGAGGACACGCAGCCGACCGTGGCCGGTGCGGTACCGACGATCTGGAATGACGTGCAGCATTTCCTGGAATCCGAACCGGAGCACGATATTTCGTCGCTACGCCTGGTCGCCTGCGGCGGGTCGGCCGTTCCAAGGTCACTGATGGAGCACTTCGAGAGTGAATTCGGTGTCCCGATCCTGCAGGCCTGGGGGATGACCGAAACCTCGCCGCTGGCAACCGTGGCGCGCGCGCCGAAGGGGACCAACGGCGAGCGCCAATGGGAGCTACGCGCTTGTCAGGGTCGTCCCGTCTGCGGTGTCGAGATTAGGCTGCGTGGCGACGATGGCCGTACCCTGCCCTGGGACGGACGGTCTATCGGCGAGATCCAGGCCCGCGGACCGTGGGTCACCGGCTCGTACTTCGGCGACAACGACTCCGACAAGCTCGACGAAGGATGGCTGCGCACCGGCGACGTGGGTCGCATCGATCAACACGGCTACCTTACGCTTACCGACCGGGTAAAAGACGTCATTAAGTCAGGTGGCGAATGGATTTCCTCGGTCGACTTGGAGAATGCGCTCGTTGCCCATCCAGCCGTGCATGAGGCGGTGGTGATCGGCGTGCCCGACGAGAAGTGGCAGGAAAGACCCTTGGCGTTGATCGTCACGAAGACCGAAACCAGCTTGGATATCAACGAATTGCGGGTCTTCCTGGACGGCGCGGTCGCCAAGTGGTGGATCCCGGAGCGCTGGGCGTTCATTGCTGAGGTTCCCCGAACCAGTGTGGGCAAATACGACAAAAAATTGCTGAGAGCACGCCACGGCGCCGGCGAATACCAGGTCGTGTACTGCGGCTAACCCGAAAAGCCGCCAACGTCGTCAGCAGCACCTAACCGAAAGGACACCATGACAGTCGCCTCACCTTGGCTCAGCCCGGAATTGGAAGCGCTTCGTGATCTCGCCGCAAAGTTCGTTGCCACTGAGATTGCACCCCACTCAGAGCGCTTCGCCGAGCAACACCATGTCGACCGGGCGGTGTGGGAACGAGCAGGCGAGCTGGGCCTGCTGTGCATGTCGATGCCGGTCGAATACGGCGGCGGCGGCGGGACGTTCGCGCACGAAGCAGTTCTGCTCGAAGAGCAAGCTCGAATCGGGGACAGTTCGTGGGGCGCCGGCCTGCACAGCGGCATCGTCGCACACTACATCCTGCACTACGCACGGGAAGACCTGAAAAGGCAGTGGTTGCCCAAGATGGCGTCGGGCGAATTGATCGGTGCCATTGCGATGACGGAGGCTGGAACCGGATCTGACCTTCAAAGCGTGAAGACGCGCGCCGTCCTCGATGGGGACGAGTACGTCATCACCGGCTCGAAGACGTTCATCACCAATGGTCAGCAAGCCGATCTCGTCGTCGTCGTGGCCAAGACCGACCATACCCAAGGCGCCAGCGGTATCTCGCTGATCGTCGTGGAAGCCGATCGCCCCGGGTTCCGGAGAGGACGAGTCCTCAGCAAAATAGGTCAGCGCGGTCAGGACACATCTGAATTGTTTTTCGACGGCGTGCGCGTCCCCAAGACGCATCTGCTAGGCGACACCGAGGGGCAAGGCTTCTTTCAGCTGATGACGCAACTGCCGCAGGAGCGACTTATCGTCGCGGTCGGAGCGGTTGCCGCCATGGAATTGGCCTTGCACCAGACGATCGAATACACGCGCCAACGAGAAGCATTCGGGCGAACGATCTTCGGGTTCCAAAATACCAAGTTCACCCTCGCTGAAGCCGCCACCGAAACAAGGATTGCGCGAGTGTTCCTCGACCACTGCATCTGTCTGCATCTCGACGGTAAGCTCGACGTGCAAACTGTCGCGATGGCCAAATGGTGGACGACGGAACGGGCGATGAAAGTCCTCGACGACTGCCTGCAGCTGCACGGCGGGTACGGATACATGACGGAGTATCCGATTTCGCGTCTCTGGGTTGATCAGCGAGTACAGAAAATCTACGCGGGGTCTAACGAAATAATGAAAGAGATTATTTCGAGGTCGCTTTGACAAGATAGCGACGACCGAACGCCCGGTGTATCAACGCAGATGAGGATCTGCTATTCGAGACAGGCAAGCTCCACTGCAGACAAAAGCCATCCCGGTGCCGTATCGGCGGACACGGCGGATCCGTCAAGCTCCCGCGGTTCCCCCTGGCCTCAGGGCTTATTCGCGGACGAGGAGTGTCCGGCTGCAGCTGTCCTCTCGCCACGATTCGTTCTCACGACGTGAATCCCGGAATCCGGCAACGCCGTCAGCCCACGTTGCCGACCTCGGCGATCTTGATTCCAGTAAGGAAACTTCTCACATGCTGCGTCGGGGGCGTGATGCATCACGTCAAGTTGCCCGCGAAACCTGATCCATGCATCACGTAAGGAATGCCCGCGAAAACGAGGTCAACTGGCGGTCTTGTTCTGGATGCGGATGCCGGATCTGACCTCGGGTAGGGCGGTGGGGATGGCGGCGAGGTAGAGGTGTTCGGTCTTGTTCTTGGCGAGTCTGAGCAGGGCGGCTTGTAGATCGGCGATCTGGCGTGCGATCGCGGCGGGGTTCAGGGTGTCGCGGTAGGCAAGCAGCTCCGATTCTTGGGCTGGCGAGAGGACCCCGGCTGCCAGCAGCCGGTCCAGTGGGGTCATGGGCTCGTCGTAGAGGCGGCGGCGCTGGCCGTCGCGGCCAGCGCCGTAGCCGATGGGTTTGATGGCTCTTCGTAATTCAGAGTGCATTGACAAGTTGGTGGAGTGCTCCGCTGTGTAGTAGTGAGCGCCAACGGTAGTGGGTGAGGTTGCGGAATCCGAGGGCGTTGCGGCGCAATGCTTCCAGGCGGCCGTTGATGGCCTCGGTGGGTCCGTTGGAGACGTGGTGGTCGAAGAAGGCCAGGATGTCTGGCAATGTCAACTTGAAGTGGCCCCAGTGTGACGGCTAGTTTTGGCCCCCCCTTCGCGGTGCGTTGGGATTTTCTGGCGTTGAGGTGGCTAGCCCCAGAAGATGCCTGAGGGGTTGTGATCGATTTCGGTGAGCACATCGTGGATGTGCGGTGTGGGGTCGATCGTGTCGTAGCGGTGAAATTTGAGGTGTCGGTCTCGCCAGTACAGGGTCCAGGTGTTGGTGGTGGCGGTGTAGCGCAGTCGTGCGATCGGGAAACTGGTCCAGTCTGGACCGTAGTCTTCGCGCCACGGCGCTCGTCGTTCGACGATGGTGAGGTGCCGGGCAGCGACGTCGCATTCGACGCGGACTTGGTGACGCGCGTGTTCGGGCACTCTGGCCGCGCACCACTGTTGCACGCGTGCGATATCGAGTTCGGGTAGGGCCATTGGGTCACCACCGGGGCGTGTCGGTGGCGGCGGTCAGGGTGTCGTAGGCGGTGTCGAGTTGGCGTTGACGGCGGCGGTGGGGTTCATGATTGGACTCGGCAGCCAGAGCATCGATCAGGTCGTCGAGTTCGGCGGCGGTCATCGTGAGATGAAGCTCGCCGCCGTGGGCGCAGATCGCGAAAACCGCTCTCTGACAGTTGTTGTCGAGGAAGGGCAGGGTGCGCAGGGTCGCTGCGGTGTCAGCGTCGATGGGAATGTCGCGGCGCGGTTGGGCTGCGGTCAGTTGCTGGCGACGCAGATCGTAGATTGATGCTGCCCAGTTGCTGATGGTGCCGTCGTCGCCGCAGTGGCTGCATTGCCAGCCGATGGGTTGCTCAGCATCGCCGCGGACCACCGTGATGCGGCCCGGGCAGCGGCGGTTGGCGGGTCGGCGCCGACACGGCAGCGCGGTTTCCCACCGGGTGTGAGCGTCGCCGGCCGACGCTGCGGAAACGATGCCGCCCAGGTGCTCGGCGAGCGCACGGGCCGGCCCGGGGTCTCGGGGCCCACGTCGAGGAAGTGCTGCAGATCGGCGACCAACATGACCTGGTCACTGTATCGGCTGCAGGCCGGCCAGAGGCGCGTGAGTTACTGCGCGGTGCTGGTGCGGCGGGTGCGGGCATGGGCGAGTCGGTAGGAGGTGGTGCCGGTTTCGATGATCTGCCCGGCGAAGGTCAACCGGTCGACGATGGCCGCACACAGTCGCGGGTCGGTGAAGGTCTTGGTCCACGCGGAAAACGGCTCGTTGGACGCGATCGCCACCGAGGCGCGTTCCTCGCGCTCGGTGAGCACCTGAACAGCAACTCCGCACCGCGGCGGTCCAATTGCAGGTAGCCCAGCTCATCGATGAGCAGCAGATCCACCCGACCGTAGCGGGTGATCAACTTACTCAGGTGGGCCTCGTCGGCGGCCTCGACGAGTTCATTGACCAGCTTGCTGGCCAGGGTGTAGCGGACGCGGTAACCGGCTTCGGCGGCGGTGGTTCCCAACCCGATCAGCAGGTGAGTCTTGCCGGTCCCGGAGTCGCCGATCAAGCACAAGGGTTCACCGGCTTTGACCCAGGCGCAGGTCGCCAGGGTGCCGATGACTGCGGGGTTGATCGCGGGGTTGGCCTCAAAGCTGAACTCGTCAAGCCGCTTTGGCCGAGGGAACCCGGCGTCATGAATACGGCGCTGCGCCCGGCGGCGATCCCGGTCCTCGCATTCGGCGATCATCAGCTCCGATAAGAACCCCAGATAGGACTGCTGTTCACGTTCGGCCGCGGCGGCGATCTCGGCGAAGCGGTCACGGATGGTGGGCAGCCGCAACATCCGGGCGCCCTGTTCGATTGCCGCGACCGCGGCCTGATCGGTGACGGTGTGACGCGCGGTGGTGTTCATGAGCTCTGCTGCCCCAGCAGCGTGTCATAGGGGGCCACCGACGGCAACGGCCGCTCGTCGGCGATCAGGCGGTGCTCAGCGAGCCGGAGCACCTGGGCGCCCTCACCGCCGCCGGGTGGCGAACCGAGGCCGGCGCGCTGTTCGGCGGCCCGGCGGGCTTCCAGCGCCACCACATCGGCATTGACCGAGCCCACCGACAGCGCAGCGCTGATACCGGCCAGCACATCAGCGCGGTCGAGGTGACGGTGCAGCAGCAGGACTTCAACCAGCACACGGGTTCCGCCAGCATCCCCATGAACCCGCCGGGCTGCGGCCCACCACGCGTCATGTTCAGCGGTGAACAGTTTGGCCGCCCGCGCTTGAGCCAGTGCGGTGGCCCCCGGCAACGCACCGGGTTTGCGGGCCAGGATCTCCAGATAGTGGTCCAAGTCCAGCACCTTGGTGCCTTTGCCGACTGCCCGGGGATGACGTGCCACCACCGTGGTGCGGTCATAGACAGTGACATGCGACGCCGACAGTTTCACCCGCACACGATGCCCGATGAACCGGGCCGGCACCGAATACTGATTGCAGCGCACCATGATCTGGGCGTACCGATCCACCCGCGGAGTCAGCGTCAACGCCGTCTCAAACCCCTGATCGGCAACAGGCTGCAGGAACTGCCGCTCGGTTTCCCAGTCCTGGCCAACACTGTTGGCGCGGTTAGCGATCCGACGACGATCGTCGGCGTCGTCAGCAGCGGCCAAGAAGGCGTTGAGCTCGTCGATGGAGTCGACCACCGGCATCGGCACGCAGTGATTGCGGCGAAACCGGCCCCCTTCGCCTTCCACGCCGCCCTTTTCGTGGCTGCCGTCGTGACCGGGCTGGCAATACCACGCTTCAAAGCCGTAGTGCGAGCGGAACGCGATCCAGCGTTCATTCTCCTGACGGGACCGTCCGAACAACACCTGCTTGACCGCACTATTGAGATTGTCGTAACGGATCTTGTCGACCGGCACCCCGCCGAGGCGGTCGAACCCGTAAACGTGGCCCTCCAGAAACGCTTCCTGGCCCTGGGTGGCGAACGCCCGATGCGCTGCTCGCCCCGAGAACGACAACCGCATCGTAAACAGTGCGGTCTTGGTCTTCACCCCGGCCAGCATCACCCACAGATCGTGGAAGTCGACCTCGGCTTCAGCGCCGGGTCGGTAGGTCTGCGGCACAAATCCCGCCTCCAAGGCCCGGCCCGCCTCCGCAGCGATCTGTGGGCGACGTTTGCGGATGTGGTCGCGCACCGTCGAATACGACAACCCGGCAGCGTCATGCTCATCGACCAGCCGCGCCAACACCCGTCGCGCGGTATGGCGTTGCTTTTTCGGGGCATCCAGATCCGAACGCAGCATCTCATCGATGGCCGCCTTGAACGGCTCCAACCGCGGCGCCGCTCGCGGCCCGGTCTTGCGCGGCGGCGGCACCGCCGAATCCAACGCTTGGCGCACTGTGCGTCGATGCACCCGGTACTTATCTGCCAGCGCCCGGATCGACAAACCCTCAACCCGACGATCCCGGCGGATCGCTGCGAACTGCTCCACCCGTGTCCTCACCTTTCCAGCCACCAACCCTTCACCAGCGATCCGGGCCATCCGGAACCGCCTGTGATCACTGTCAGGTGGGGCCAATTCACGCCGTCATAACCGACGCGGCGTGTCGTCAAGGTGGGGCCAACTCAGACCGTCACAACAGCACACCCGCGACCACACAGGTGGGGCCACTTTCGACCGCCCACCCGGGGCCAAATCAGGCTGTCACAGCCAGATGTCGGCGCGGCGGCGCGATAGCGTGCGGCCGAGTTGGGCGATCTCCTCCAATCCGGCGGGTACGCCGCGCCGACTTCCAGGCGGCCGTTGATGGCCTCGGTGGGTCCGTTGGAGACGTGGTGGTCGAAGAAGGCCAGGATGTCGGCGCGGCGGCGCGATAGCGTGCGGCCGAGTTGGGCGATCTCCTCCAATCCGGCGGGTACGCCGCGCCGTATCGACTCGATCAGCCTGGTCATTGCCTTCTTGCCGTGACGTCGGTTCGGGTCGGCGTAGGCGGCGATGATCTTCTGATAGATCAGCCAGGCGACCTTGACGGCGAGATGGTCGTCGCCGTCGAGCACCTCGGTCAGCCGGGTGTATTGGCGTGGGGAGAGCAGCTGCAGGCGGGTTCGGGCGATGCGCCGGATCCCATAGAGCGGGTCACCGGTGTGTCCGCGCCGACCCAGGGTCTGCTGCTGGATGCGTTGGCGGATCAGGTCGAGCTTGGTCCCGGCCAAAGCCACAACGTGGAAGGGGTCCATCACGGTGACCGCGTCCGGGATGACCTCGGTGGCGGCGGTCTTGTAGCCGGCGAACCCGTCCATCGCAATGACCTCCACGGCCCGGGCAAAGTCGGTGGGTTGGGCGGCCAACCACGTGGCCAGTGCGGTCGCTGAGCGTCCTTCGACCAGGTCGAGCAGGCGTGCCGGGCCGGTCTGGTCGTGGGTAGGCGTGAGGTCGATGATCAGCGTGACGAACCCCTCTGTGCCGCGACGCCGAGGCGCCCAGCGATGCTCATCGACACCGATCACCGTCACCCCGGCCAGCCGATCCGGCCCGGTTGTGGCGATCAGGCCGGCGGTCGCACGCATCGCGATGGAGCTGACAGTATGCCAGGACACCCCGAGTTCGGCGGCGATCGCCGAAATGGTGGTGCGGTCGATCATCAACCGCCGCAATACATACCGGGCACAGCGCCGCGTCGTCGATGAGCGCGGGGCCGCCAACTTGCCCAGATCCTGGTTGAACACTGCCCGCCCACACGCTGGCGTTGTGCAGCGGTAGCGAGGTAGGGCACCCTGCAGCACCAGCGGGTAGCCGGCCACCGGCAGATCCGTCAACGGCCGAGTCACAGTGTCGCGGTAGCGGCCCTCCCGGCCGCAGTCCGGACACCTGGCGTCACAGGCCACCGGCCTGCAGAAGATCGTCGTCGTCTTCTCGTCGACCGCGGCGTCGGTGATCGTCACCCCCAACTCGATGGTGCGCATGATCGTGTCGGCAACAACAGACGGCGGGCAGGCAGTAGCCTCAGGCAAGGGTCACCTCGGTGGTGTTGGTGAAGCGGCGTGTAGGAACCTGAATCGTCACCCACCGAGGCCCCACCTCAGCTCAACGACACGAACCCCCACCGCGGATATCCGCCAACCACTGCTGCACGCTCATTTCCGCAGAGCCGGTTTGATGGTGGGCGTCAGGTAGTTGAGCCGGTCGTTGACCAGCCTCCAGAGCCGGTTGAGCACCGCACGTTCCTCGTCGGTGTCATAGCGGTAGTAGAACCCATACTTGCGGACGAGGTGGTTGTTCTTGGACTCGATTGTGGCCTGATCGTTCTTCTTGTACGGCCGCGACCTGGTGAAGAAGATCTCCATCTGCGCAGCCCACTTGATGACGGCCTTGTTGAGGAATTCGGTTCCGTTGTCGAAGTCCAAACCGGTTACCTCGTAAGGTATTTCATGGACACCGGCTTTGAGGGCGCCGAGGATGTGAGTGTGGGCGTTGTTGCGTTCGGTGCGGGTGAAGACCCAACCGATATGCATATCGGTGAGGTTGACGGTCCGGGCGAACTCGCCTTTGAGGGTTGGACCGCAGTGCGCGACGGTGTCGCCTTCGAAGAACCCCGGAGATCCCTCGACCTCGTCGGTTGCCTTGCGGATCTTGATCGAAGACCGCAGCAACGGGGAGGCCTTGGTGGTCGATTTCCCCTTGATCTGGTCGCGCGCCTTGACCGCACGCAGGTAGCGGTCGATCGTCGCGCTGCTCATCGCCAACAGCTCGGCACGCACCTGCGGGCTGTAGCGGTCCACACCTGCGCGTCCGGCCGGGTTTCCAGCAGGCGAGGTACGACGCGGCGACCAATAAACCCGGTACCGCCGGTAACGACATAGCGCATGCAAGCCATCGTGGCGGGTCACACCGCGCACGTCAACCATGCTGTCCAGGCATCAGCCGGCGAAGTTGCGGATGCCGTCCCAGTCCACCAGCGTCCAGCCGGTCATCGGGTTTCCGGTGATCACCACGCGGCCGACGTTGGGCAGCGGATGACTGGTCGCCAGGCTGTCCTTGGCGTTCTTCGTGTTCATCAGCGTCCAGTACTCGATGGCGTACAGATGCGAGAACACCACCGGTTGGTTGTGGCCGCTGTTGTAGATCTTCTGCACGGCCGCGGTGAACCAGTCGTTGAACTCCTTGCCGGTGATCGACCCGGGGATGCGGTCTCCGACGTCGCCGTTGAGCCAGTCCGCCGGTACGTCGAGGGGGCCATCGAGACGGGCTTGCCCTCGTACCAGCCGGCGTTGATCTCTTGGATGCCTTGCAGCACCTCGACTTGCTTGCCGAGTTCGGCGGCCAACGGCGCGGCGGTCTGTTGCGTTCGCACCATGGTGGAGGCGTAGACGGCGTCGTACTTGTTGTGGGCGAGTTGGTGCGCGACCTGTTCGGCCTGCCCCTTGCCCTCCGGGGTCAGGCCCGGGCCCGGCACGTCGGTGTCGATGACGCCGCTGGCGTTGGTCTCGGACTCCGCGTGCCGGACGAACGTCACGGTGATGCTGTGGGCCTGCGGTGACCCGCCGCAGGCGCCGACGATTACCGTTGCGGCCAGCACGGCTACCGCTTTTGAGGCCTTCCTGATCAAGCTGGGATTGCGCATGGCGATAGCCTGCCCCGCCGACGGTGCCGGTGGGAAGGGTTTGCGATGGTTGGGTGGCAGAAAAGCTTGAAGGGAGACTCGTATGGCGATTGACCCGAGTGCCGTCGGTGCGACGACGGAGCCGATGCTGTTCGAATGGACGGACCGGGAGACGCTGCTCTACGCGCTCGGTGTCGGCGCCGGAACTGACGACCTATCGTTCACCACCGAAAACAGCCACGACATCACCCAGCAGGTGCTGCCCACCTATGCGGTGATCTGCTGCCCGGCGTTCGGTGCGGCGGGCAAGATCGGAAAGTTCAACTGGGCCATGCTTTTACACGGGTCGCAGGGCATCCGGCTGCACGCACCGCTGCCGCCGGCGGGCAAGCTGTCCGTGGTCTCCGAGGTCGCGGACATCCAGGACAAGGGCGAGGGCAAGAACGCGATCATCGTGCTGCGCGGCCGCGGCACCGACCCCGACTCGGGGGAGCTGATCGCCGAGACACTCACCACGTTGGTCATCCGGGGCGAGGGCGGGTTCGGGGGAGTGCCGGGTCAGCGGCCGATCGCGCCGGAGTTTCCCGACCGCGAGCCCGATGCCCGGATCGCGCTGCCCACCCGTGCGGACCAGGCGCTGATCTATCGGCTCTCCGGTGACCGCAACCCGCTGCACAGCGACCCGTGGTTCGCCAGGGACATGGCCGGTTTCCCGAAGCCGATCCTGCACGGGCTGTGCACCTACGGGGTGTCGGGCCGCGCGCTGGTCGCCGAGCTGGGCAAGGGCGTGGCCGCCAACGTCACGTCGATAGCGGCGCGATTCACCTCGCCGGTGTTTCCAGGGGAGACGCTGACCACGCTGATCTGGCGGACGGAACCGGGCAAGGCGGTGTTTCGGACGGAGGCTTGTGGCGCCGAAAGCGCGAACGCGCGGATCGTGTTGGACGACGGCGCGGTGGAGTACGCGGAGGCCTAGCCGATGGCTTAGAACCCGGTACGTCGCCCCGGCGCGCAGGCGTTCACTGGTGCGCCTGGCCTGCCGTCCAGCCATGACCTGTCCCGCATTCGGCGGGCTTCGGGGGGATCGCTCGGGCGCTAAGCTAAACAGCTATGTGCTACAGTTAGCACATGTCTACGGTGGGCGTTCGTGAGCTGCGGCAGCGGGCCAGCGAACTCCTCCGTCGGGTCGAGGCCGGCGAGACGATCGAGATCACCGACCGTGGTCGGCCTATCGCCCTTCTCTCGCCGATGCCGGAGGGCGGTCCGTACCAGCAGATGCTGGCAAGCGGCGGGATCGAACGTGCGACGCTTGACTTTGATGACCTTCCCGAGCCGGTCCGACTCAAAACGGGTATCGAGCTGCCGTCCGTGACGCTTGCGCGCCTGCGTGAGCACGAGCGTTGATGGCGGCCATCTACCTGGACTCGTCCGCAATCGTCAAGCTTGCAGTTCGTGAGCCAGAGTCGGATGCGCTGCGTCGCTACCTTCGCACCCGGCTGCCGCGGGTGTCGAGTGCCCTTGCGCGGACGGAGGTCATGCGGGCTCTGCTCCACAAGGGTGAATCAGCCCGAAGAGCCGGACGCCGGGCGCTCGCGAGCCTAGACCTACTACGCATCGACAACCGATTGCTCGATCTTGCTGGTGGGCTGCTGCCAATCGAGCTACGCACCCTCGATGCAATTCACCTGGCGACTGCCCAGCGGCTCGGCATGGATCTTGGCCGGTTGTGCACTTACGACGACCGCATGCGCGACGCCGCCGAGGCGCTCGGCATGGCAGTGATTGCCCCGTCTTGATCGGCTACCTAGGGTGGCGCGTGAGGCGGCCAACGCTTCATGTCCCGGCATGTCGCGCCAACCTCGTGCCACCGCCGAATGGGGACACCGTCGTGCTGGATCACTCGAATGTTGGCACCCTGAGCGCCGTTAGAACCGTTGCCGTCGCTAATTTACGCGGGCGTCACTTAACCGCTGTGCCAACCTTTCGGTGAACTCGGCGGCGCGCGCGGGACTGTCCAACGCAAACAGCGCGGCGGTGGCGCGGTCGCCGTCTTCGCTGTGTCGCACCAGGATCGGGATACCATCATCGCGGACCGCGTCGAACGCGTCCTCGTCGGTGATGTCGTCGCCGAGATAGATGGGCACCAGCGGACGCGCGTCGGCCTCGCGCAGGTGATCGATCACCCAGCGAAGCGTCTTTCCCTTGTCCCAGTCCATGTCCGGACGCAGCTCGATGACTTCTTCGCGACCCGTCGTCACCCGAAGTCCGTCCCGCCGGCCCGCCGCGCGCACCGCCGCGGCAACCTCGCCCACGCGGTCCCGCGCGGCGTTGCGGTAGTGGACCGCAACGCCAAATCGCTTGTGCTCCATCATAACTCCGGGGATCGAGTCGAGCCGGTCGCGCAGCTCGGCGGCGGCCTGTTCGAGCACCGGTGTGGCCGCCGCCGCGGCGTCGTTCTGGTGGTGTGTGCCGTCGGGTGCGGTCAGCTCGAAACCGTGGCTGCCGGCATACCAGATCCCGGGCACACCGAGGCGCTGTGACACGTCGGCGAGGTCGCGGCCGGACAGAACCGCGACCGGGCATTGCGCGGCCAGCTTCCGCAGCGCCTCGACCGCGGCGGCGACGGGCCGGGCCGCGGCGGGATCGTCGACGATGTCCGACAGCGTGCCGTCGAAGTCGAAGAACATATGGCCGGCCTCCGGTCGGTGAGGGCACCGAGGGCCTGCACAGCATCGGGTAGCTGGGACATCCGGTGGTCCCCGGTGCGCACGGCGACCTCATCCAGATCGCCGACCACGGCGTCGGCGCCGACGCGCCGCAGGGCGTCACTTTGCCCTGTTCGGTCGAGGCCGATGACCAACGCGAATCCGCCGTCGCGCGCGGCCTGGACGCAAGCCGCGTTGTCGGTAAGGACGGCGCATCGCCCCGGGCGGACCGACAGCTTGTCTGCTGCCTCACTCAGGGTGTCGCGGACGTTACCGTTCGACGCGAAGACGCCGGTGTCGACGCCGGCTTCGCGCAATCGCCGGGTCAGCGCCTGGGTGCGGTCCAACGCGGTGTCGAACAGCACCGCGTCATGGCGGCGCGGGTCGATGGTGACCGGCATTGACCAACCTTCTCACGGTGTTCAACGCCGGTGAGAGCGGGTCAGTGACGTGCCGGCGTGGGTGCCGACGGTCGCGGCCGCTGCGCCTGGCCCGGAAACGCGCGCGCCGCGCGCGTGCGCCGGCGGTCCTTGCTGAACAGCAACACCGAATCCTGGCTGAGCGCCACCATCCGTGCCATGCCCAGCTCGATACCGGCTGCCAGCTGCTTGACGTCGGCCGTGGCGTCGTATTCGGCGGTGATGCCCGAATACCAATTCGTCGCCGTAGCTGAGCATCGCGACCCCGGTGCTCAGCTGCAAGGCGATCGGGGGGATCGGCAGCAGGCGCTCCATCGTCTGGCCCATCAGCCGCAGCTGATGGCGAGGCCCGGGCGCGTGGTTCGCCAGCGTTACGAGGCCGCGCTGCGGGAGCCTGGGTAACAGTTGTATGAGGTTGCCGCGCAGCATAGTTGGCAGACAATTGATCGCAGACTCCACGATACCGGGCGGAGATTTGTCGGCGTGCTGCGCTTTCCACCGGCTGTGCACGGTCCGCAATTGCTGGACCGGGTCGTCATGCTCGACGGGCAGGTATGGCAGTAGTGCCGAACGTACCGGCATCGGCACCAGGGTGCGCAGCGAGTCCGCCCGCGGTTCTTCGCCGCGGCGTAGCAGAACCCTTCGGAAGCCCTCGGTGATGGCCGCCAGCGCGACATCGTTGACGGTCACACCGAATTTGCGGCACACGCACTCGACGTCGGCAATCGGGACGCGCACCGTGCTGTAGCGCCGCAGGACCGGGTCGACCGAGGGCCGTGCCGTCGGCCAGATCGCCCCGACGAAGTTGCCGGCGAGTGCCCCAGCCCACTCCAGGGGCCAGCCGCGCTTCGAGGCCTGCGGCGGCGAATCATGTTTGTCGCCAACACCGTTCGCGAATGCATCGTGGTCGGCGTCGTCGCAAAGCCGGGTGAGCAGGTGGGCGGCTGAGTTCCCGTCGGCCAAGCCGTGGTGGATCTTCATCAAGATTGCCCACCGGCCGCCTTTCAGGCCCTCGATCACCCAGCACTCCCACGGCGGACGGTCCAGGTCGAGGGGACGCTCCAGGGCGTGGGCGATCGCGCCGGACAGCTGGGCGTCGTCGCCCGGGCGCGGAATCGCCACCCAGCGCACATGATGGGCCAGGTCGAATCCGGGACAGTCGATCCACTCGAAGCTCTGCGTCCGCAGCACCTGTGTGCAGCGCGGTATCGACTGAATCCGTTCCGCCAGCAGCTGTTTCAGCAGTGCGTAATCGGGGACGCCACCATCGACGATGGCGACCGCGCCGATCACCAGGCTGGCGTACTGATCGGGATCTTGAGCTCTCAGGTACGCCGTATCCAGTGTTATCGCTTGCGCCATGCGCAGTCCCCGCCCCTCGTTTCTCGCACTTGTACCAGTATTTGCGCGGGACCTCCGGGGCGGTAGGCCAGGAGCGTTAAGAATGTGTTTAGACCCGTTAAACAGCTCGCCTAAGTCGAACATACTTATTGCTTATCTGCTTAAGTGGACTCGTTTGCTTAAAAAAATTCGTCAAAAGTACTGCCGGGCAGTGGTTTAGCAGTTGCTCGCAGAGTTTGCTCTTGGCCTTCGGCGGCGCCGATGAGGTCGGCTAGTGGGTGGGGATCGGTGTTGACGCTTTGTTGCAGGAGTCGGTAGAAGAGCATTCCGCGGGCTTTTGACCTGCGGCGATTGAATCTGAAGGTGAACTCGTCGAGGTAGTACTGCAGGTGCTCGCGTTCCACGCGGGTGTAGCGGCCATGACAGGAGCGATCGTCGGCGCCCGCGACGGCGTTGAATCCATCCCTGCTCGCTGGCTCGAAGCACTCGAAGACGGCGACCGCGGACGCACCCACGTGAAGCAGCTCGCCGCGCTTCTGCTCAGGTAGCGCGCTCTGCGCCCTACCCCCCCGCTCACCTAGGTGCGTGGGTCGGTATCCACGAGTTGTTGGTGTGTCACGCTGATGGCGACGTGGATGGTCGGGAAAACTGTGTCCATGGATTTGATGACGGCCCAGGATCAGCTGTTTGAGACCGAGTCCGCGCGGCCTCGCTCGTCATCGTCACCGGGCGAGGTTTCGGTGGACAAGACGTTTCGGGCCTATGACCAGGATCAGTCGTTTTTGATGCCGCCGTCGTTGCGGGATTGGTTGCCTGACGATCATCTGGCGTTGTTTGTGTCCGAGTTGGTCGATGAGGTGCTTGATCTGGCAGTGTTTTTCGCCTCCTACAGCGAGGCCCGGGGCTTTCCGCCGTATCACCCGCGGCTGATGCTCAAGCTGCTGCTCTACGGGTACACCAGCGGGGTTCGTTCATCTCGCAAGATCGAAGCCCGTTGCCATGACGATGTGGCGTTTCGGTACCTGGCCGCCAACACCGCACCGGACTTTCGCTCCATCGCCCGCTTTCGGCGCCGTCACCTCGCCGCGCTGGAAGCCCTGTTCCTGCAGGCGCTGACCCTGTGCCAGCAGGCGGGCATGGTCACGATGGGCCGGGTGGCCCTCGATGGCACCAAGGTCAAGGCCAATGCCTCCCGTCACAAGGCGATGAGCTATGACCGGATGTGCGAGGCGGAGCCGGCCCTGCAAACCCAGGTCGAGCAGATCATGCGGGAGGCCGAACGCGTCGATATCGACGAGGACCAGGCCCACGGCCCGGACAATCGTGGCGGTGACCTGCAGGGCGAATTGGCCCGCCGTGAGAGCCGGCTGGCCAAGATCCGCAAGGCCAAGGCCGACCTGGAACAACACGCCAAAGACCAGGCCGCGGACAAGGCCCGGGCAAGGGCGCAAAACGCCGGCCATGATGACGACGCGGCCGCGCGGGCCGCCGAGCAGGCAGCACAGTGCGCGACCGTCAAGCCCAAGGCGCAGCGCAACTTCACCGACCCTGACGCCCAGATCATGAAGACCGCCGACGGCAGCTTCCACTACTGTTACAACGCGCAGGCCGTCGTCGATGAAGAACATCAGGTGATCGTTGCGACCGACTTCGCCGAATCCGGCGCCGACAACCCCGCATTCGGCGAGCTGCTCGCCCAGACCATCACCAACACCGCGACCACACCGCGTCAGACGCTCGCCGACGCCGGCTACTTCAGTGAGAACAACATCGACGCCGCCCACAAGGCGGGCACCGATCCGCTGATCGCGACCGGCCGGCTCGCCCACGGCGAGCAGGTTCCCGACGCGCCACGGGGACGGACACCGAAAAATGCGACACCAAAGGCGCGGATGGCCCGCAAACTTCGCACCAAGAAGGGCAAGGCCGCATATTCGCGGCGCAAGGTGATCGTCGAGCCGGTGTTCGGGCAGATGAAGACCACCCAGGGGGCGAGTCGACTCCTGCTCCGCGGCCACCATCACGCCCGCGCCGAATGGCGCCTGCTCGCCGCCTGCCACAACCTGCGAACCCTCCTACTACAACATTGCAGCGCAGGCTGCGGCCGGCTGAAAGGGTCGTGCGCAGCGAGTTACGGCCACCGATCCGCCATCCCGCGGAATGCGGCCCGCCCGATCACACCACCAGGCCAACAAAACGCCGCCCGATGCCCTCCGTCCAGGACAAATCCACCTGCCGACCCGACAAATCCGTTACCGACCCACGCACCTAGCCGGGGGGCAGCAGGAATCAAGATCACTACAAGTCAAGTCCCCACGGAATCAGGGGAACCCCTTCACCCGAGCTGCACGGCGTATTGACGGCAGAGCACCTACGATTGGCCGCTGATCAGCCCGCACCCTACTTTCCCGTGCTGGTGACCGGTGCCGCCGCCTCGGCTCCACCGGCGGCAAGCTCACCCTGGTCCGCAGCACCCACTGTCTTTGACAGGCGAGCACCCAGCCGCTGAAATGCGTCCACCGAGAATGGCTGCATCATACGGCGGTTGACACCAGGGGCGATACGGAGCATGAAATAGCCCAGCCAGGCCTCGGTGCGCACCGGCACGACCGCCAAATCAAACCGTACCGCACGTACGACGGCACGAGCTACGAGGTCCGAGCTCATCGGCGAGACCCTAAACTTCTCGCTAAATTCCTGGAGCTTCTTCGTGAACTGCTTTCCTTGTTCGATCAGGTTCTGATCGACGCCGACTACGATCGCGCGATCAGCGATGTTGGTGTTGATCACACCCGGGCACACGGCGCTGACGCCGATGCCTCTCGGTCCGAGTTCGAGCCGCAAGCACTCGGTCAGCATCTTCACGCCCGCCTTGGACACCGAGTACGGCGCCATCACCGGCGTGGGTGTGAACGCCGCCGCTGACGCGATGTTGACGATGTGGCCACCGCCGCGCTCAACCATCTGGGCGCCGAACACACGACATCCGTGGACGACACCCATTAGGTTCACACCGAGTTGGCGGTCCCCGATGACGGGGAAGGGAGGCACCGCGCCCGCCTCCCACAGCTTGAACCCGGTCGCGCAGATCAACACGTCGATCTCGTGCTCCACGCCGTCCGCCGTCCGTACCCCCTTCTTGGTAATGCACTCGATCGCATCGGTGACCAGGCTGACGTCGTCGCGGTTGAAGGTACGCAAGTAGTCGTTTGACATCGACGGGCGCTTGCAGCCTAACCCGTAGCGTGGGATCAGCTTCTCCCGAACGACCGGGTCATCGATCTGGCGGCGCATCCAGCGGCGGGTAGGAACCTCAAGCATCCGGCGGCTCGCGTTCGTCAGCCACTGTGGACCGACCCACATCCCGGCCATGCCGACCTCGGTTGCGACGGTTCCCACCAGGCGGATACCCGAACGGATTCGCTTACGCCCCAGAACCCACCGGATGGCGGACGTGACCTCCTTGTCAGGTTTTGGGAACACCCATATCGGTGTTCGTTGGAAGACTGTCAAATGTTCGACTTCGTCGACAATGGCCGGGACGACCTGCAGCGCCGTTGCGCCAGTGCCGATGACCGCGACGCGCTTGCCCGCCAGCGCCACGTCATGGTCCCAGAGTGCGGTGTGCATGAGCACACCCCCGAACTCGTCGAGACCCGGGATATCAGGCATCTTCGGGCGTTCGAGGCCACCGACCGCCATGACTACATTTCGGCCGGTAATCTCCTGATCGGCGTCGGTAGTCAATCGCCATAGGCTATTGCGCTCATCGAGCACCGCCGAGGTGATCGTAGTGTTCAGCCGCAACTTTTGAGCTAGGCCGTACTTGTCCACAAGGTCGCTGGCGTAATCGCGAAGCTCGTAACCCGGAGCGAAGATCCGCGACCAATCACCACGCTGCTCGTAGGAAAAGCTGTAGACAAACGAGGGAATATCCACCGCCACACCCGGATAAGTGTTCGCATGCCAGGTGCCGCCCACCTGATCCCACTTGTCGACAATCACGAAGTCGTGAATGCCTCTGCGTTGCAAGGAGATACCAGCACCGATACCGCCGAATCCAGCGCCGACGATCACGACTTCATGGTCTGGAGTGACACGCTCGACAGTCGGTAACTGCTCGATGTCGATCGTTGTACTCAACTTGAACTCATGGCCTTCCTGCTACTTGAGATGACCGACAAGGGCACCGTCGTCGCCGAACAGCTCCTGCCGCCACTGCTGCACCAGCGCGGTCGTGTCGATGTCGTCGGGATGGAAGCCCGGCTTTAGGTACATGCGCAGATCGGCCATCAGCCCCTGCACCAACGGGTCCCGGAACACCGCACGCGTTTGACGCGCCACTTTGATCGGGCGCCATCCCCGCGGATCGGCCAAAATAGACAACAGCACCCCGATCGACACCACCGGGATCGTCAGGATGTACAGCACCGCCATCACCCCGATCCGGAGCCACTCCGGCCCATCGACGGCCCGGTAGACGTCGAACGCCACCGACTTATGTTCCAGCTCTTCCACCGCGTGCCAGTTGAGCAGGTTTCGCACCTCGGGATCGCCAGGAATCTTTTGTATCTCTTCGCCCAGCATGCGCTCAGCCAGTGTCGCGGTGTAGTGCTCGGCCGCCGCCGTGACCGCCAGGGGTACCCGCGCTGGCAGCAGGTTCTCAATTCGCACGATCAACCGGCTCCCGGCGGCTGTCATGCGGGAACATAAACAGCCGGACAATCGGGTAGCCCATCTCGATGAGCTTCTCGTTGAGCCGGCGGTGTTCCTGGCCGTGCACCGACTCCTGGCCAAATGAATCCGGCCACCCGCTTCATCAGTACCGGATCGGTCATCTGATCGGCAAAGCGCCGAACCGACCGGATAAACAACTCCTCACCTGGCGGAAACACGCCGGACAGCAACGCCACAAGGTGGCTGAACACGATATTGCCCTCAACGAAATGGTGGTCCATCGGCTCGGGATCGCCGAACCAAAACCGAATCCGCCGAGCCTTAGGATACGTACTCTCGGCTACTTTTTCGGCTGCTGTTCCGCTTTTCGCAGCCATTGCCTGACTAGCTACCATGGCAATCCCTTTTGTTGTGGATGTTCGCAATCACTTCAGGTAGCCGACGAGTTCTCCGTCGGTGCCGAAGAGTTCCTCTTGCCAGTGCTCCAACAACGCGTTCGTGTCGATGTCGTCAGGATGGAATCCCGGTCGCAGATATTTCGTAAGGTCTGGGATCAAACCCCGGAAGATGGGGCCACGGTACAGCCGATAGGCCTCCCGTATCACCCGTAGCGGCTGACGACGCCCATCCGGGTCGTGCGCCAGCGAGTAAACCAATGTGACGGCTATGAGGAGAAGCAGGGTCGGAATCATCACGGCCATCACACTCCTGCGCATCCGCTCCGTACCTCCCGCCACCGTGCGGAAGACATCGAATGCGACCGATTTGTGCTCAAGTTCCTCCACGGCATGCCAGTTCAGCACGTTCCACACCTGCAACTCGCCCGGAATCGCCTGGATTTCCTCTTCGCCCAGCGTGCGCTCAGCAAGTACGGCGGTGAAGTGTTCTGCAGCTGCTGTTACCGCCAGGGGTAGCCGCGCAGGCAGCCGCTCCTCCAGTCGCTTGACCCAGTCGTTAAACTTCTTCGAATCCCACCAAGCGATCGGGTAACCCATGTCGATGAGTTTCTCGTTCAGCAGGCGGTGTTGCTGTCCGTGGACCGATTCCTGGCCGATGAAGCCCGCCACCCGTTTCTTCAACGTGGGATCGGTGACCTGACCGGAAAATAGACCCAGGTGACCGGACGCGGCGGAGCCACCCGGCGCAGCCGGGTGTTCTTTCTCGCAGTTGTCGGGTTGTGTTGTGGGAGTTGGCCGGTGTCAGGCGACGGGTTCGAGGGTGACGCGATAGCCCAGGGCTGCGAGCTGCGCGACGTGGTTACGGGTCCGGCGTTCGGTGTTGATGCGGGTCGCGTGGTAGTCGGCACCGAGATCGTGGAAACGGGCCGTGGGGTCGTGCAGCAGGTTCCAGATGATGACCAGGATGGATCGGGCAACAGCGACGAGGGCCTTGAGCTTGCCGCGGCGTTTGACGATGCGCCGATAGCGTTCACCGAGGAAGGTGTTGGTCTTGGCAGCGGCTGTCGCGGCTTCGCCGAGAGCACCTTTCAGATATGGGTTGCCTTTGCCCGCCTTGCCCGAACGTTGCACCGGACCGGACTGGATGGTGCGTGGACACAGTTTTGCCCACGACACCAGGTGTCCGGCCGTGGGGAACCGGCTCATGTCGAGCCCGATCTCGGCGAGAATGATCTGCGCGTTCACCGGGCCGACGCCGGGAATCTCATCGAGTCGGTCGATCGTGGTCAACTCGCCGGCTTTGCGCGAAGCGGGGTTTGCTCCGCCGGTGGCGTCCCCACCGTTGACAGGTTCGGGCTCCATTGCAGCCAACAGTTGGTCGATGCGGGTGGTGAGCCTGCCGATCTTGGCGTCCAGCGCGTCGATCTGATCGAGCAGCATCTGGGCAAGTTCGGCGTGGTGATCGTCGAATCTGCCGGTCAGCGCCTCGACCAGAGCGGCTTGCTTGGGTCTCATCTTGCCGCGCGCCAGCCCGGCCAGCCGGCGCGGGTCCCGCTCGCCAGCGATCAGCGCCTTGAGCATGTCGCGCACCGACAGGGTGTCCAGAGTCGAGGCCACCGACGACACCTTGATCAGCGCGTCCTCGAGCAGCTTCTCGATCCGTTGCCAGTACCGGGAACGTTCGCGAGTCATATCGATCCGTAACCGGGTGTAGTCGCGTAACTCGCGGATCGGCGCCGGCGGCACGAAACTTGGCCGCAGCAGACCTTTCTCGGTGAGCTTGGCTAGCCAGACCGCGTCGAGTTTGTCGGTTTTGGGCCGACCGGGCACGTTCTTCACGTCGCGGGCGTTGACCAGCTGCACGTCGAGCCCGGCCGCCTCCAGCAGGTAGTACCAGATCCGCCAGTAATCCGACGTGGACTCCACAGTGACCTTCTCAATCCGCTCGTCAACGAGGTAGTCGGTCAACTCACCGACTGCGCCGGACGTGGCGGCCACGTCCCACACTTTGCTGACCCGCCTGCCCGCGCGGCTGCCCACACGCACGCACACCTTGCCCGAGGCCTTGGCTACATCGATCGCGCACACACGCTCGATCACCAACTCATGCTCGGTGTCAGCAATCTCCTCCGGCTGCTGCTGCTTCAACTCGCTTGCCCTCCATCAACATCGACGCTCTCAACAAGGCGGGCCGCCCGGGGGCCTCGGTTCAGGGAATCGAAATTCTGACCGGCGTGCTCGAAGCAACAGTGCGTGACCCTTCCAGGTCGGGCCCCGGCACCAGGCTCATCAACAGGCTCACAAAACCCAAGTTAACGTCGGCGTCGGCAGGCAACCCGACCCCCATTTTCACGCCTGCGAGGCGTCACCCGAAGGGAAACAGGGGGCTCATCTGAGAATCGACGCACCGACCGAATAAACAACTCCTCCCCTGACGGGAACGCACCCGATAGGTTCGCCACGAAGTGGCTGAACACGATGTCGTCGTTGACGAAGTACTTGCCGTGTGTGCCGCCGTCGCCGCCAAACGGAAAGCTTATCCGTCGGGTCCTCGGATAACGGGATCCAGCGCTCGCTGCGGTCACCGACTTTGCCTCTTGCCTTGCGTGGTCACTCGCCATGAATGCTAGCCCCTTCCTTGAACGTGTGACGTGTAGTTCCAGGTACCAATAGTACTAGGTGTTGGAACCACGCTACTGCGGATCCACGAGGTCGGCAAGCATCCGGCAAGCATCACGAAAAGTGCCCGCGAAACGCCCTCGGTGCATCACGTAAGAATGCCCGCGAAACGGTGATCCCCGCCAGGCATGGAGAGTGGGCTGTCGATGTCGTCTCGTGCCGAGATCACCGCGAAGTTCGCCAAGGCGTATGTGAAGGCGTCGAAGGCGAATAAGGGGCAGATTCTGGATCAGGTGGTGGAGGTCACCGGCTGGTCGCGTGACAATGCTCGGCGCCGGTTGACGGCCGCGGCCCGGCCGCCGGGAGCGGGCCGGCAGGTCGCCAAACGACCTCGCCGGCAGCGCAAGCCGAAGTATTCCTATGACGCGCTGAAGGTGCTGGGCCACTGGAGCGAACGGCGACGTGCAGTGTCGGTTTGTCGTCGTCTGACTCGTCTGGGCGGGAGACTTGATCCCACATGGTGTCGATCATCGGTTGCAGGAAGAGCTGTCCCAGCTGTCGGACCATGATGTCGATGATCTGGGTGGATCCGCTTCGCTCCGCATTTGCGATACCGGCGTCGCGGGCTTTGATGAGCTCCGTTCGGGTCAGCTCTGTCAATCGCTGGAGCAGTTGGCCTTTAGACCCTGCGGGGTCCAGTAGCGCGCGGCGCAGATAGTTGACGACGGCTGGGTTCGATTCGAGCATCTCCTTCACAGCCACGTCACGCGCCGTGGCGACTTGTCTTGGTGTTCCATCAACGGGGACCTGCGCGATCGTCTGCGCGAAGTAGTCGACGACGAGTTGTTCAACGGCGCGGCGGATTCCGTCCTTGGTCTTGAAGTGGTGGACAACCAGCCCGACCGTGACGCCGGCTCTCGAGGCGATATTTCGCATCGACGTGCGGTCCTCCCCGAACTCCGCGAACAGGTCCATCGCGGCGTTGCGAATGCGCGCCTTCGCGGTCAGGTCGTCTGCGCCTGCGCGTGGATCGGCGAACGGTCCCATGCGTCTCCTTCGTTCCGGGCAAGTGTACAGTGAACATCACTTCTTGTACAGATAGGAAGCTTCCTGTACAGTCGTACGGTATCAATTGAAGGACCACATGGTGCAGGGCAGTCTGAACGGCGTTCGCATCGTGTCGCTTGCGGTGAACATCCCGGGCCCGCTCGCGGCGGCACGGCTGGCGCGCTTCGGCGCGTCGGTAACAAAGGTGGAGCCCCCTACCGGAGATCCCTTGGCCGCGGTCGCGCCCGGCTGGTACGCAGAGCTCGCCAGCAAGCAGACGGTCTTGGTTCTGGACCTCAAGGACGCCGGCGACCGCGCCAAGCTGGACGTCGAGCTGACTTCCGCCGATGTGTTGCTCACCGCCATGCGCCCTTCGGCGCTACGCAGGCTCGGGCTCGACGACGCGCATGTCAGGTATCCGGGGCTCTGTCACGTCGAAATCGTGGGCTACGACGGTGACCTCGAGGAGCGTCCTGGCCACGACCTGACCTATCAGGCCACGCACGGCACCCTGCAGCCCCCGTTGATGCCGGCGGTTCCGGTCGTGGACCTCCTGGGTGCCGAACGTGCCGTGTCCGGGGCCCTGTTGGCGCTGCTTGATAGGCCGAATTCCGGTGCCGGCCAACACGTCCGGATCGTACTGGCGGACGCCGCAGCCGACGCCGGCGCAGCCGTGCGGTACGGCGTCGCAGGGCCCGGCGACCCGCTCGGTGGCGCGACTCCGACCTACGGGATCTACGCCAGTGCCGACGGCTATATCGCCCTGGGCGCAATCGAACCGCATTTCCAGAAGCGGACCCTCGAGGTCCTGGGCGCAGCAGATACCCACGAGGATCTCGCACGAGTCTTTGCCGGACAAAGCACGCGCCACTGGGAAGAAGTCGCCGAGACGGTTGACATCCCCATCGTTGGAATTCGTACACCGGAACAAGGAGGAGTGGAACATTGAACGCGCGCGAAGCAGTGATTGTCGGGGCGGTGCGCACGCCGGTGGGTAAACGAGGTGGCGCTTTGAGCCGGTGGCATCCGGCCGACTTGCTCGGTCACACCTTGCGAAACCTGGTGGAGCGCAGTGCGATCGATGCCAAAGACATCGATGACGTCATCGTCGGCTGTGCGATGCAGCATGAGCACCAGTCCGGAAATATCGGGCGGCACGCGGTGCTGGCTGCGGGTCTACCCGAATCGGTGCCGGCGGTCACCATTGATCGCCAATGCGGGTCCGGTCAGCAGGCGGTCAACTTCGCTGCATTCGGCGTCACCGCGGGCATCTACGAGCTGGCGATTGGGTGCGGTGTGGAGTCGATGTCGCAGGTGCCGATGCCTGCGTCGTTCATGCCGGGCGCGCCGCTCGGTCCGCAGTACTCGCCCGTGGAGTTGGCCCGCTACGACGACAACTTGGTGGCGCAAGGGGCGGCGTCGGAGTTGCTGAACTCCAAGTTCGGTATTTCTCGCGAGGAACTCGACGAATTCAGTATCCGAAGCCATGAGCGAGCATTCGCCGCGACCCGGGCGAAAAAGTTTCGCGCGCAGTTGGTGCCGATCACCGTCGATCCGCTGGATCCGTCGGCGGCGCCCGTCAGTGCCGACGAAGGAATCCGTGAGCAGTTGGATCCGGCGAAGATCGCGTCGCTGGAGCCTGTTTTCGCGGCCGACGGCCGCACAACCGCGGCCAATTCTTCCCAGATCAGCGACGGGGCAGCGGCGTTGCTGATCGCCGAGCGTGGCTACGCAGAACGCAGCGGGCTGGTTTCGCGGGCGCGGTTCCTGGCGATGACGGTCGCCGCGGCGGACCCGGTACTGCAGTTCACCGCGGTACTGGACGCCACCCACAGGGCGCTCGAGCGCGCCAACCTGAGTGTCAGCGACATCGACTTGTTCGAGGTCAACGAGGCCTTCGCCGGGGTGCCGCTGATGGTGCAACGCGAGTTCGGCATTCCCGATGACAAGCTCAACGTCAACGGAGGCTCGGTCGCAATCGGGCATCCGCTCGGGTCGACCGGGGCCCGCATGCTCACCGATCTGCTGTGCGAACTCGAGCGCACCGGACAGCGCTACGGCCTGCAGACCATCTGCGAGGCCGGCGGAACCGCCAACACCACCATCATCGAACGAATCTAAGGCACAGACATGGTCAGGGAAATCGTGAAGGGCGTGCCGTCGACGCACGGCGACCACTACCAGCTCAACACCACCAACCTGATCAGACATGCGGCGCGCACCTATCCCGAGCAAGAGGTCGTCTACCGCACCACGGAGGGCGACTGGCAGCGGTACACCTACGCAGACTTGTACGTTCGGGTCAAGCGGGCGGCGAACGCGCTCAGAGGAATAGGGATCGGCCCGGCCGACACAGTCGGAGTGCTCGACTGGAACAGCAAGCGGCACTTTGAGCTCAGCTGGGCCATTCCCGGCATCGCCGCGGTGATGCTGCAGATGAATCTGCGGCTGGCCACCGAAGACCTGAGCTACGTCACTGACCACGCCGAGGCGCAATGGATCCTGGTCGACGAGACACTCCTTCCGGTCGCCGAGGCGTTGGCTCCACACGTGCCGAAGGTCAAGGGCTGGATCGTAATGTCGGATAAGCCGCTCACCGAGATCGACACCACGCTGGAAAACGTCTTTCACCTCGAGGACCTGATGGCCGAGTCCGACACCGAGATCGACTGGCGGGTCATCGACGAAACCTCTGCTTACAGCGCGTGTTACACATCGGGAACGACGGGTCGGCCGAAGGGCGTCTACTACTCGCATCGTGGCAGCTACCTACACGCGATGGCGATGGCAGCAGCGATCAATCTCCGTCGCGAGGACACCGCGATGCTCATCACCCCGATGTTTCACGGCCAGTCGTGGGGGCTTCCGCACACCGCGATGTGGACCGCGGCGAAGGTGATCCTACCCGGCCGCTACCTGGCCGAGAACACGCAAATGCTCGTCGACGTGATGATCGCGGAGAATGTGACCGTCGCGAACGGCGCACCGGCGATTTTCCAGCCGATGCTGGACTACATCAAGACCCTTGCTGTGAAGCCAGATTTCAGCAGGACGAGACTGCTGTCCGGTGCGACCGAGCCGGCGAAGTCGCTGATGCGCGATTTCCACGAGCTCACCGGCGCCGATTTTGTGCAGGGCTACGGTGCGACCGAGACGACGCCGCTGATCACGATGAACATGGGCATCAAACCGTCCCTGCAGGGCACGATCACCGACGACGAGAAATGGGATTTCAAGCGTTTTCAAGGGCTGCCCGCTTCCGGTATCGACATCCGGATCGTCGACGACAACGGCAATGACCTGCCGCACGACGGTAAGAGTGTCGGCGAGGTACTGATGCGTGGGCCCTGGGTCATCGAGCGATACCACCAGCTCGACGACGACGACAACGCCGACCGCTTCCTCGACGGTTACTGGCGCAGCGGCGATGTCGGCACAATCTACCCGAACGGGTATCTCAAGCTCACCGACCGCCTCAAGGACGTAGTCAAGAGCGGCGGTGAATGGATTTCCTCTATCGATATGGAGAACGCCATCGTCGGACATCCGCTGGTGAAGGAGGCCGCGGTTGTGGGGATCAGCCATCCGAAGTGGCAGGAACGTCCGCTGGCCATCGTCGTGCCCGTCGAAGGTGGCGTGCTGACCCGCGATGACATCGTCGGTTGTCTGCAGGGGCAGTTCGCCAAGTGGCAGATGCCCGACGCGGTTCTCTTCGTCGAGGCGTTGCCGCGCACCAGTGTCGGCAAATTGGACAAGAAGATCCTGCGGGCCGAACACGCCGACGTTTACCGGGATGCGGTCACGTGAACAAACAAATTTTGCGATCGACTCGCGACGGTGCGGTGGCCCTGCTGGAGATCAATCGCCCGAAGTCGAAGAACAGCCTCAACGACGAGCTGTTGGGCGCGATGGGGGCCGAGCTGGCGGCGTTGCGGTCCGACACGGCCGTGTTGGCCGTGGTCATCGCGGGCGCCCACGGCATGTTCTGCGCCGGCGCCGACATCACGGCGTTCGACGAGATCCGGGCCCGGCCACTGGTCACCGGAGAGTCCAATGAGAGCTTCTGGTCGATACTGGCTGCGTTTCCGAAGCCGGTCATCGCCGCGGTCGAGACATACGCACTCGGGGGCGGCTGTGAGCTGGCGTTGGCCTGCGACATTGTCATCGCCGGCGAGTCGGGCCAATTCGGACTTCCCGAGGTGAAGATCGGCGCAATCCCTGGCGCTGGCGGAACTCAACGCCTCATTCGGGCGATCGGCAAATCCAAGGCTATGGCAATGCTTTTGACGGGCGATTCCATCAAGGCCCAGGAGGCGTGCGATGCAGGGTTGGTAGCCGAAGTCGTCGCCGACGGCGAGGCCGTGCCACGGGCGCTGGCGATGGCGCAACGGATCGCGACGAACTCCCCGCTAGCGGTGGCGCTGGCCAAGGATGCCGCTGTGCACGCGTTTCAGACATCACTGACGCAGGGACTCGAACACGAGAAACGGAATTTCTACGTGGCGGTGCATTCCGCCGACAGTCACGAGGGCCAGGCGGCATTCCTCGCCAAGCGCGGGTCACGTCCCGTGGAGTGGTGTAAGAGCGGTCGCGTGTCCGCGTGTGGCTCTGTGGTAGCCACTATGCCGTGAGAGCGGCTGTGGGGGCAATGGTTTCGGCACTTTGGTCACTGACGTCGAGCAGAGCGAGGCTGGTCTCGGAGAGGTAGCGCTTGTCGGCGACCTGCCATTCGTCGTGGGCCTCAACGAGTACCGAGCCGGCCAGCCGTAACAGCGCGGCGGGGTTGGGGAACACGCCGACGACGTCGGTGCGGCGTTTGATTTCCTTGTTCAATCGCTCCAGTGGGTTGGTTGACCAGATCTTTTTCCAGTGGGCCACCGGGAAGTCGGCGAAGGCGGTGATGTCGGCGGCGGCCTCGCGCAACATGGTTTCGACCTTGGGGAACTGGCGGCCGAGCATGCCGGCGATGGTGTCGAGTTGTTCGCGCACGTGCTCGGCGTCTGGCTGGGCGAAGACGGTGCGGATCGCGGCGGCGACCATCTCTGCGGAGCCCTTGGGCACTTGGGCGAGCACGTTGCGCAGGAAGTGCACTCGACACCGCTGCCAGGCGGCCCCGATCAGCACGGCGTCAATGGCACTGCGCAGTCCGGCATGGGCATCGGAGATGACCAGTTGGACTCCGGCCAGACCGCGGGATTTCAACGACCGCAAAAACGCGGTCCAGAACGCCCCGTCCTCGGAGTCTCCGACCTCAAAGCCCAGTACCTCGCGGCGCCCGTCAGCGGCCACCCCGGTGGCGATGACCACCGCCTGCGACACCACCCGATGATTCACCCGGGCCTTGCAGTAGGTGGCGTCGAGGAAGACATACGGAAAGCGCTGATCACCCAACGGCCGGTCCCGGAAGGCCGCGACCTCGGTGTCGAGGTCTTTGCAGATCCGGCTGACCTCGCTTTTGGAGATCCCGGTATCGGTACCCAGTGCCTTGACCAGATCGTCGACCTTGCGGGTGGAGGTGCCGTGCAGGTAGGCCTCCATCACCACCGCGAACAAGCACTGATCGACCCGGCGACGCCGCTCCAACAACGCCGGGAAAAATGACCCGGTGCGCAGCTTGGGAATCCGCAGTTCCAGGTCCCCTGCGACCGTGGACAGCGTGCGCGGACGCGAGCCGTTGCGCTGATTGGAGCGGGTCTCGGTGCGCTCATGGGGAGAAGCCCCGATGAACGCGGTCAACTCCGCGTCGATCAAGGCTTGGTAGATCGTTTCGGCGGCTTGAGTGATCCGCTCACCGGCATCGGCGGTGCGCAGTGCGTCGAGCACCTCCAGCAAGGCAGACTGGTCCAGGGCCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP040250|1610556:1690873|1652499_1653168_-|WP_023900852.1|DBSCAN-SWA
MRTKAKRWGGRTGAERRAERRQRLIDAATEIWSESGWAAVTMRGVCSRTSLNDRYFYEDFKTRDELLVAAWDGVRNEMLGEVSATLAERVGQPPLETIRMTISMVVDRITQDPGRAKILLTQHVGSSPLQDRRAVALQEATHLVVAASKPHLRPDADETALRMDTLVAVGGFVELITAWHAGLLDVSQEEIVEHTSRLAETLAERYLVHALSVDDVPGTLPS
>NZ_CP040250|1610556:1690873|1635235_1636129_+|WP_057969464.1|DBSCAN-SWA
MPVRWSVVAADDWAVAGLESQGQHPHDWLKHPSRERTWLFKPARPERDRSLGEDTVEKLGSEMARLVGVPAATVELATRGGVRGALVEDVRLPEWELQAGQALMPEVVIDYDPTDPEARGYNVGSIRQALTRFGSPPGSSMPTSFRAFDAFAGYLLFDALIAHGDRHDRNWAVLVPPPDVSEPSFDHAASLGFTLSDELRAEHLRDGTVMKWAERGHASRFEHRKGTRWQTLVDLAGDAIRLCGPSTREYWRERILSLERRTVEDLFASAPGMTETAHRFTVELVKINRERLLDVLA
>NZ_CP040250|1610556:1690873|1663272_1664415_+|WP_033712837.1|DBSCAN-SWA
MTVASPWLSPELEALRDLAAKFVATEIAPHSERFAEQHHVDRAVWERAGELGLLCMSMPVEYGGGGGTFAHEAVLLEEQARIGDSSWGAGLHSGIVAHYILHYAREDLKRQWLPKMASGELIGAIAMTEAGTGSDLQSVKTRAVLDGDEYVITGSKTFITNGQQADLVVVVAKTDHTQGASGISLIVVEADRPGFRRGRVLSKIGQRGQDTSELFFDGVRVPKTHLLGDTEGQGFFQLMTQLPQERLIVAVGAVAAMELALHQTIEYTRQREAFGRTIFGFQNTKFTLAEAATETRIARVFLDHCICLHLDGKLDVQTVAMAKWWTTERAMKVLDDCLQLHGGYGYMTEYPISRLWVDQRVQKIYAGSNEIMKEIISRSL
>NZ_CP040250|1610556:1690873|1637514_1638564_+|WP_007172498.1|integrase|DBSCAN-SWA
MRVLKSDSGYVLEGDWDGQDAVNAFLNHLAGRGFSAATVRAYAFDVANLSRFLVQQAVGLAAVDAPLVFDWIDWQGVRRTDQPTGGHRSSTPPAASTVNRRVAAVRALFEYLVMTGVCTDNPVPSPRRGQGLRQSQRGLLGHLGPGRARSGGRLVRQPQRLPESLSTNDVDAFLATLATHRDRAMVLVMLLGGLRSAEARGLLLADVDMGRRRLRVIGKGGKERHVPVDAAFFTELAAYLRWERPPGLATPQCFVVLRGPTTGAPVSEAGLRSLFRRHRETSGATRVRPHRLRHTYGTELSAAGIDLLALRALMGHVSPETTARYVHLSIEQLAAEYGAARATLAGARQ
>NZ_CP040250|1610556:1690873|1673217_1673610_+|WP_007168407.1|DBSCAN-SWA
MAAIYLDSSAIVKLAVREPESDALRRYLRTRLPRVSSALARTEVMRALLHKGESARRAGRRALASLDLLRIDNRLLDLAGGLLPIELRTLDAIHLATAQRLGMDLGRLCTYDDRMRDAAEALGMAVIAPS
>NZ_CP040250|1610556:1690873|1621396_1621735_-|WP_062887574.1|DBSCAN-SWA
MALPELDIARVQQWCAARVPEHARHQVRVECDVAARHLTIVERRAPWREDYGPDWTSFPIARLRYTATTNTWTLYWRDRHLKFHRYDTIDPTPHIHDVLTEIDHNPSGIFWG
>NZ_CP040250|1610556:1690873|1680443_1680980_-|WP_007168415.1|DBSCAN-SWA
MTAAGSRLIVRIENLLPARVPLAVTAAAEHYTATLAERMLGEEIQKIPGDPEVRNLLNWHAVEELEHKSVAFDVYRAVDGPEWLRIGVMAVLYILTIPVVSIGVLLSILADPRGWRPIKVARQTRAVFRDPLVQGLMADLRMYLKPGFHPDDIDTTALVQQWRQELFGDDGALVGHLK
>NZ_CP040250|1610556:1690873|1685117_1685969_+|WP_007168421.1|DBSCAN-SWA
MVQGSLNGVRIVSLAVNIPGPLAAARLARFGASVTKVEPPTGDPLAAVAPGWYAELASKQTVLVLDLKDAGDRAKLDVELTSADVLLTAMRPSALRRLGLDDAHVRYPGLCHVEIVGYDGDLEERPGHDLTYQATHGTLQPPLMPAVPVVDLLGAERAVSGALLALLDRPNSGAGQHVRIVLADAAADAGAAVRYGVAGPGDPLGGATPTYGIYASADGYIALGAIEPHFQKRTLEVLGAADTHEDLARVFAGQSTRHWEEVAETVDIPIVGIRTPEQGGVEH
>NZ_CP040250|1610556:1690873|1650822_1651692_-|WP_033712834.1|DBSCAN-SWA
MTSESPTRPAKRVLPKARRVRFAMPAGTSRQHFVDGDLVMSHFVSTLSATFPEGEDFFIRSVRQYRDQVSDPDLQEAVKGFIAQEATHRHQHRLLNERLQAMGYPTDGIDRHIKKLVDRLEKRFSPKMRLAVTAALEHYTATFAEIILTSDEAQELIGDTEVRPILLWHALEESEHKAVAFDVFETVGGTERTRVWGMRIATVILFTELVIQTTRSLAGDRAAYNPLRLLRSLRAFRRSPLFSPDAVQRFRSYTRAGFHPDDWDSTEVLERWAKELFDSDGAQRIGSRV
>NZ_CP040250|1610556:1690873|1644358_1644574_+|WP_019732564.1|DBSCAN-SWA
MAELGIKGISPRRFKTTTVVDPASFPPDLIGQRFDKGRLDAVWSSDIERREALFNRTEVRDHRRRAIAVAR
>NZ_CP040250|1610556:1690873|1688823_1689651_+|WP_138017754.1|DBSCAN-SWA
MNKQILRSTRDGAVALLEINRPKSKNSLNDELLGAMGAELAALRSDTAVLAVVIAGAHGMFCAGADITAFDEIRARPLVTGESNESFWSILAAFPKPVIAAVETYALGGGCELALACDIVIAGESGQFGLPEVKIGAIPGAGGTQRLIRAIGKSKAMAMLLTGDSIKAQEACDAGLVAEVVADGEAVPRALAMAQRIATNSPLAVALAKDAAVHAFQTSLTQGLEHEKRNFYVAVHSADSHEGQAAFLAKRGSRPVEWCKSGRVSACGSVVATMP
>NZ_CP040250|1610556:1690873|1610556_1611690_-|WP_019732805.1|tRNA|DBSCAN-SWA
MRIGPIELASPVVLAPMAGVTNVAFRTLCRELERELVGTVSGLYVCEMVTARALVERHPATMHMTTFAPDESPRSLQLYTVDPATTYAAAKMIADEGLADHIDMNFGCPVPKVTKRGGGSALPYKRRLFGQIVAAAVRATQGTEIPVTVKFRIGIDDEHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIALLKQQVRTIPVLGNGDIYDASDALTMMAATGCDGVVIGRGCLGRPWLFAELSAAFTGSPPPTPPTLGQVADIVRRHGRLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSELRRALAMVTTLDELDRLLDRLDGSVPFPDEATGPRGRQGSPARVVLPEGWLDDPDDCTVPAGADVMHSGG
>NZ_CP040250|1610556:1690873|1664801_1665128_-|WP_033711234.1|DBSCAN-SWA
MHSELRRAIKPIGYGAGRDGQRRRLYDEPMTPLDRLLAAGVLSPAQESELLAYRDTLNPAAIARQIADLQAALLRLAKNKTEHLYLAAIPTALPEVRSGIRIQNKTAS
>NZ_CP040250|1610556:1690873|1687150_1688827_+|WP_007168424.1|DBSCAN-SWA
MVREIVKGVPSTHGDHYQLNTTNLIRHAARTYPEQEVVYRTTEGDWQRYTYADLYVRVKRAANALRGIGIGPADTVGVLDWNSKRHFELSWAIPGIAAVMLQMNLRLATEDLSYVTDHAEAQWILVDETLLPVAEALAPHVPKVKGWIVMSDKPLTEIDTTLENVFHLEDLMAESDTEIDWRVIDETSAYSACYTSGTTGRPKGVYYSHRGSYLHAMAMAAAINLRREDTAMLITPMFHGQSWGLPHTAMWTAAKVILPGRYLAENTQMLVDVMIAENVTVANGAPAIFQPMLDYIKTLAVKPDFSRTRLLSGATEPAKSLMRDFHELTGADFVQGYGATETTPLITMNMGIKPSLQGTITDDEKWDFKRFQGLPASGIDIRIVDDNGNDLPHDGKSVGEVLMRGPWVIERYHQLDDDDNADRFLDGYWRSGDVGTIYPNGYLKLTDRLKDVVKSGGEWISSIDMENAIVGHPLVKEAAVVGISHPKWQERPLAIVVPVEGGVLTRDDIVGCLQGQFAKWQMPDAVLFVEALPRTSVGKLDKKILRAEHADVYRDAVT
>NZ_CP040250|1610556:1690873|1671917_1672790_+|WP_007168405.1|DBSCAN-SWA
MAIDPSAVGATTEPMLFEWTDRETLLYALGVGAGTDDLSFTTENSHDITQQVLPTYAVICCPAFGAAGKIGKFNWAMLLHGSQGIRLHAPLPPAGKLSVVSEVADIQDKGEGKNAIIVLRGRGTDPDSGELIAETLTTLVIRGEGGFGGVPGQRPIAPEFPDREPDARIALPTRADQALIYRLSGDRNPLHSDPWFARDMAGFPKPILHGLCTYGVSGRALVAELGKGVAANVTSIAARFTSPVFPGETLTTLIWRTEPGKAVFRTEACGAESANARIVLDDGAVEYAEA
>NZ_CP040250|1610556:1690873|1645103_1646552_+|WP_007168383.1|DBSCAN-SWA
MNTSALWPDPDTAELRVRRMQRKLHHWAVDESDRCFDDLYNLVYDPAFLTLAWERVRTNKGARSAGADGTAPRSVGAAEAVGLLQRLREELKERIFRPDPVREVMIPKANGKLRRLGIATVADRVVQASLKLVLEPIFEADFHPCAYGFRPGRRAQDAIAEIHHLASGSRAYHWVFEGDITACFDEISHSALMGRVRRRVGDKRVLALVKSFLKAGILSKDLGYRDTITGTPQGGILSPLLSNVALSVLDEHFAAKWKALGPEWTRAKHRRAGVPTMKIVRYADDFCVMVHGTRADAEALWDEIAAVLAPMGLRLSVEKSRICHVDEGFEFLGFRIQRQIKRGTTKHYVYTWPSKKALMSITDKVRNLTRRHKHRTLADLLRQLNPVLRGWCNYFQHGVSKRTFDYLDHFTWWRVVTWMRKRHHGLAWGVFHRRFLPNWQIREGKTAMFRPQKVEVTRYRYRGTKIITPWTARPTDITAPVA
>NZ_CP040250|1610556:1690873|1654157_1655081_+|WP_007168394.1|DBSCAN-SWA
MAFEYGDMLQTIKDRQWALADIDWDAPGAELITDEQRPSLKQFMSDVVWIEHVGARAFAAMAPKAPFDALGEIYRYFHAEEQRHANVELALMHRWGMLEEGETPVPNKNIRLVIEWLDRYAEALPLTVIGAAIPALETALDGALLKFLVDEVSDPVCGEVFAKVNSDESRHLAVGFQVLNDLGASPMRIHAIQTVGALIDPRVLTGALLYIPLLTRMLINLNAWGLSEERLYNAVTRYSNVGDRSEHTRRVPPYHILKAHMSATIKHSQPLHFISQRLGRVIDHFPTQVLGKTPSWTDELTYEPVAR
>NZ_CP040250|1610556:1690873|1647259_1647889_+|WP_085981614.1|DBSCAN-SWA
MPTESVRLSFRRHMREQVLRAARTLTIEKGWDRVRMGEVAELVGVSRPTLYKEFTDKQGLGDALVVAEGERFLNGIHAVLAQHAGDVGGGITAAVSYTLKEAEASPLLKAVLTSNRPTDRTVAESTGMLPLLPTSASLLELSSAALVTWFNEHFSGLDANDVNDVADALVRLTVSHVVLPTADAETTGERISRIALRYLGVHSSAGEAR
>NZ_CP040250|1610556:1690873|1678679_1680422_-|WP_138017753.1|DBSCAN-SWA
MSTTIDIEQLPTVERVTPDHEVVIVGAGFGGIGAGISLQRRGIHDFVIVDKWDQVGGTWHANTYPGVAVDIPSFVYSFSYEQRGDWSRIFAPGYELRDYASDLVDKYGLAQKLRLNTTITSAVLDERNSLWRLTTDADQEITGRNVVMAVGGLERPKMPDIPGLDEFGGVLMHTALWDHDVALAGKRVAVIGTGATALQVVPAIVDEVEHLTVFQRTPIWVFPKPDKEVTSAIRWVLGRKRIRSGIRLVGTVATEVGMAGMWVGPQWLTNASRRMLEVPTRRWMRRQIDDPVVREKLIPRYGLGCKRPSMSNDYLRTFNRDDVSLVTDAIECITKKGVRTADGVEHEIDVLICATGFKLWEAGAVPPFPVIGDRQLGVNLMGVVHGCRVFGAQMVERGGGHIVNIASAAAFTPTPVMAPYSVSKAGVKMLTECLRLELGPRGIGVSAVCPGVINTNIADRAIVVGVDQNLIEQGKQFTKKLQEFSEKFRVSPMSSDLVARAVVRAVRFDLAVVPVRTEAWLGYFMLRIAPGVNRRMMQPFSVDAFQRLGARLSKTVGAADQGELAAGGAEAAAPVTSTGK
>NZ_CP040250|1610556:1690873|1622363_1623155_-|WP_062895396.1|DBSCAN-SWA
MNTTARHTVTDQAAVAAIEQGARMLRLPTIRDRFAEIAAAAEREQQSYLGFLSELMIAECEDRDRRRAQRRIHDAGFPRPKRLDEFSFEANPAINPAVIGTLATCAWVKAGEPLCLIGDSGTGKTHLLIGLGTTAAEAGYRVRYTLASKLVNELVEAADEAHLSKLITRYGRVDLLLIDELGYLQLDRRGAELLFQVLTEREERASVAIASNEPFSAWTKTFTDPRLCAAIVDRLTFAGQIIETGTTSYRLAHARTRRTSTAQ
>NZ_CP040250|1610556:1690873|1665377_1665716_-|WP_062887574.1|DBSCAN-SWA
MALPELDIARVQQWCAARVPEHARHQVRVECDVAARHLTIVERRAPWREDYGPDWTSFPIARLRYTATTNTWTLYWRDRHLKFHRYDTIDPTPHIHDVLTEIDHNPSGIFWG
>NZ_CP040250|1610556:1690873|1615381_1615915_-|WP_019732396.1|DBSCAN-SWA
MHEAARTTLQFVTDFARRTIDLARQNVAEGGRPFATVIVQDGEVLAQSANKAAQTNDPTAHAEILAIRAACRKLGTEHLVDATIYVLAHPCPMCLGALYYCSPREVIFLTTRESYEPYYVDDRKYFELANFYAEFAKPFDERRLPMRYQPHPDAVDVYRLWNERNGGRRRSTVVPSD
>NZ_CP040250|1610556:1690873|1655077_1656724_+|WP_007168395.1|DBSCAN-SWA
MSDTTSVLIIGAGFAGLGTAIQLLKRGIDDFVILERAGEVGGTWRDNSYPGAACDIPSLLYSYSFEPNPDWSRAYSGSSEILAYIKAMVDKHALARFICFHVNVTGLAFDEDSGTWTVETDGGSSYRSRTVVMASGPLANANFPDIRGLHSYAGHKIHSARWDHDYDMSDKRVAVIGTGASAVQIVPELVKTARSVKVFQRTPGWVLPRPDFPHPSVAKAAFGRLPILQSAARQAWFWAHEVMAVGMVWNTPATTAIAWAAKANLRRQVKDSWMRRQLTPDFRPGCKRMLMTSDYYPALRQNNCKLITWPIATISPIGIRTADGIEHEVDCIVFATGFDVCKAGTPFPITGVDGRKLAEEWSNGAYAYKSVSVSGYPNLFFTFGPNSGPGHNSALVYLEAEIRYIVDAIGIIIEGGIQTFDVKEDRQNSYHAQLQRRLAGTTWNSGCKSWYLTEDGYNGTMYPGFTTQFARQLARVELDDYSMSSQPPPRKKPRRARPELAAESSHGASKGGRQRNDDRVSVDKREGVRFSAQTASPEAASPRMVDRA
>NZ_CP040250|1610556:1690873|1647976_1649278_+|WP_007168386.1|DBSCAN-SWA
MIASTTSALKTSAERRSARPYDSADLSSTAFWAGTAADREKTYAELRKRAPISWHPRVEHTMIDDGNDRGFWAVVTHPLLVEATRRHDDFLSGQGIVMESIPQELLDTAQGFIAMDPPRHTKIRRLLASAFTPKQMRLIHHQIEANAKRVVDDLAPQGKADFVDECAALLPMHNIFDMMGVPDSMRRDIAWESRYAGGWSDPEVMGDDPVIPRLFQAMGFLGDGAREIIAARRRQPEDDLMTNLVQAEVDGEKLTEDEIVSFFILLTIAGNDTTRQSTSHAMKALTDFPDQRAWLMEDFDGRIKGAVEEFVRWATPIMTFRRTAARDCDLGGQQITEGDKVVLFYSSANWDTTVFTNPEKFDLSRDPNPHVSFGGGGIHHCLGNQLARQQLAALFRELLHRLPDIEVCGPPSYTVSTFFHGVNHLPVRFTPTT
>NZ_CP040250|1610556:1690873|1643414_1644311_+|WP_007168381.1|DBSCAN-SWA
MTVTLERFRTTDGVTLTADCYRHDAARAVVLLLHGGGQNRHAWATTARRLHARGYTVVAYDARGHGDSAWDPTGRYDLGRLASDLLAVREHASTDRPPAVVGASLGGMTVLGTHLLAPADLWGAVVLVDITPRMEFHGARRVVSFMAAHPDGFSTLDDAADVIAEYNRHRTRPKNPDGLRKVLRQRDDGRWIWRWDPAFITSNFQFLQGDPATGAEKFDAISELLVEGARRVQAPTLLVRGVLSDVTSQQSVDEFLKVVPHAQAVDVSGTGHMVAGDDNDAFTAAVAGFLDRTISTSA
>NZ_CP040250|1610556:1690873|1617910_1619938_+|WP_132160402.1|DBSCAN-SWA
MSSGQFIVLTGALGTGKSDRAEGWIRSAAELAQSDPDAPLPVWVAIDDLESSLEVHLQREVGVLALETVGADIVIDGLDQRADRAERTIGYADSLTRRWPRSRVVLTSRATHNVRDSVVIRVDPMPKSYGRKLVSLVAGTAQVGDLRPEIEEALERPLFALLIGQQASSGELTTMTEVIEGVVRKVVGREDKDLYPHLRQLAIRTTTTARPVDPESFVDFDVASKLRDSPFLTTTAHGLSFSLATFEQWFASRAVLEEAVSLDDILVDLPSFDRWKYVLSIVLASGEPSRVDPVMARIARWNPGAIGWIINETESAGLNRYREDSSDSQQQMGYRLRFALEAMLDGLGPLSAAFTPFATTGLDSLEHFSLGLEYGGERVSTTWLISNQVPDNPLPPLIDASVEVSTNRWFSIETAAMPASRNWVWAAARNILAGDLSECLTSVAIRIASQHDGVVRREVEDLRRRNVTDPTDLDDIGRGLYGSIYPLPDVMPGRNGWPGFSLESVAKRVRAVIEAAIQCYIELCDSVAPNFGDTLAHKGMMPFEYYADMSYGGSGSGGPFSLGPAEPGIRWLLRPIGTPLPNGQRHGNNAVNITINDETRSAEIRDDKQAFGDAYFEYIANTPGLKPFSDSFSISTGRFDIIDKKPATHIAVGWLWDDLKNLKWVSGLKPNDRTE
>NZ_CP040250|1610556:1690873|1670947_1671079_-|WP_138017752.1|DBSCAN-SWA
MRYVVTGGTGFIGRRVVPRLLETRPDAQVWTATARRCVPSCWR
>NZ_CP040250|1610556:1690873|1660918_1661575_+|WP_007168400.1|DBSCAN-SWA
MKTEFARFLAATEFLDWKHDAVQQFTESATRNATDSVDKACRIFTAVRDSIWYDPYSVSDDPRQYRASAVAVAERAYCVPKAVLLTAACRAAGIPARLGFADVRNHLQTASLRERMGGSDVFVYHGYSQILLNGRWVKATPAFNRELCARFRVAPIEFDGQRDAMLHAYTGDGSQHLEYLHDRGVFDDLPLTEIIDALRDNYGELIYEPPPVPDSFTN
>NZ_CP040250|1610556:1690873|1683666_1683975_-|WP_007168419.1|DBSCAN-SWA
MASDHARQEAKSVTAASAGSRYPRTRRISFPFGGDGGTHGKYFVNDDIVFSHFVANLSGAFPSGEELFIRSVRRFSDEPPVSLRVTPRRRENGGRVACRRRR
>NZ_CP040250|1610556:1690873|1656798_1658322_+|WP_007168396.1|DBSCAN-SWA
MDHSDKHRFEIIVIGAGFSGIGMGIKLLKAGFSDFLIVDEADDVGGTWHWNTYPGIAVDIPSYSYQFSFEKRSSWSRTYAHGNELKDYARHCAHKYGLSPRIRFAVKVTEAWFDEDATLWRLHTAAGQDLSARFVINASGVLTRPKRPDISGVDDFGGITMHTSRWDHNEDIAGKRVAVIGTGASAVQLIPAIAKDVKALTVFQRTPIWCLPKLDFPVPRLARGFLKYAPGGQLAARAASQTFVEVTFPVAAHFHTAIPLASLIERAALRYMRSQVTDPAVRQKLTPRYALGCKRPSFHNEYLATFNRDNVHLETSPISHFDAAAVHTVDGRSHEIDVLILATGFKVMEPENMPTYSLRGIGGLDQAKWWDENRLQAYEGVSVPGFPNHFSIFGPYGYNGSSYFTLIEAQTRHIVRCLHHARSRHANYVEITRQANDRFFAEMLKRRHRQVFWQPSCATANSYYFDKHGDVPLRPTTTLESFWRSRTFDLGDYSFERRTTEKVLSSS
>NZ_CP040250|1610556:1690873|1681381_1682071_-|WP_080576326.1|DBSCAN-SWA
MGLFSGQVTDPTLKKRVAGFIGQESVHGQQHRLLNEKLIDMGYPIAWWDSKKFNDWVKRLEERLPARLPLAVTAAAEHFTAVLAERTLGEEEIQAIPGELQVWNVLNWHAVEELEHKSVAFDVFRTVAGGTERMRRSVMAVMIPTLLLLIAVTLVYSLAHDPDGRRQPLRVIREAYRLYRGPIFRGLIPDLTKYLRPGFHPDDIDTNALLEHWQEELFGTDGELVGYLK
>NZ_CP040250|1610556:1690873|1672942_1673218_+|WP_007168406.1|DBSCAN-SWA
MSTVGVRELRQRASELLRRVEAGETIEITDRGRPIALLSPMPEGGPYQQMLASGGIERATLDFDDLPEPVRLKTGIELPSVTLARLREHER
>NZ_CP040250|1610556:1690873|1682155_1683457_-|WP_109233510.1|transposase|DBSCAN-SWA
MVIERVCAIDVAKASGKVCVRVGSRAGRRVSKVWDVAATSGAVGELTDYLVDERIEKVTVESTSDYWRIWYYLLEAAGLDVQLVNARDVKNVPGRPKTDKLDAVWLAKLTEKGLLRPSFVPPAPIRELRDYTRLRIDMTRERSRYWQRIEKLLEDALIKVSSVASTLDTLSVRDMLKALIAGERDPRRLAGLARGKMRPKQAALVEALTGRFDDHHAELAQMLLDQIDALDAKIGRLTTRIDQLLAAMEPEPVNGGDATGGANPASRKAGELTTIDRLDEIPGVGPVNAQIILAEIGLDMSRFPTAGHLVSWAKLCPRTIQSGPVQRSGKAGKGNPYLKGALGEAATAAAKTNTFLGERYRRIVKRRGKLKALVAVARSILVIIWNLLHDPTARFHDLGADYHATRINTERRTRNHVAQLAALGYRVTLEPVA
>NZ_CP040250|1610556:1690873|1615969_1616866_+|WP_019732395.1|DBSCAN-SWA
MARTDRDRWDLATSVGATATMVAAQRALSSDANLIDDSYAAPLVRAVGIDVYVRLVNGEIQPGTSEFDPHRMARGMACRTRFYDDFFLDAARAGVGQAVILASGLDARAYRLPWPAGTVVYEVDMPDVIEFKTLTLADLGAQPTAQRRTVAIDLRDDWAAALREEGFDPQAPAAWSAEGLLVYLPEQAQDALFDNITALSAPGSRLAFDFVPDTAVFADPRWRAHHDRMSELGFEVDFNDLVYHGERSHIVDHLSGRGWQVTSRTIAELHAANGFAYAADDVAAAFADVTYSSAVLGG
>NZ_CP040250|1610556:1690873|1685965_1687141_+|WP_019732177.1|DBSCAN-SWA
MNAREAVIVGAVRTPVGKRGGALSRWHPADLLGHTLRNLVERSAIDAKDIDDVIVGCAMQHEHQSGNIGRHAVLAAGLPESVPAVTIDRQCGSGQQAVNFAAFGVTAGIYELAIGCGVESMSQVPMPASFMPGAPLGPQYSPVELARYDDNLVAQGAASELLNSKFGISREELDEFSIRSHERAFAATRAKKFRAQLVPITVDPLDPSAAPVSADEGIREQLDPAKIASLEPVFAADGRTTAANSSQISDGAAALLIAERGYAERSGLVSRARFLAMTVAAADPVLQFTAVLDATHRALERANLSVSDIDLFEVNEAFAGVPLMVQREFGIPDDKLNVNGGSVAIGHPLGSTGARMLTDLLCELERTGQRYGLQTICEAGGTANTTIIERI
>NZ_CP040250|1610556:1690873|1614676_1614880_-|WP_011723747.1|DBSCAN-SWA
MSEQHTHDAPHTHEHQHGGVTHAHAHTTHEHDHVEHEHSHAHTDGTEHTHRHVHQAGLEDVHQHAHA
>NZ_CP040250|1610556:1690873|1621739_1622318_-|WP_062895398.1|DBSCAN-SWA
MLVADLQHFLDVGPETPGPARALAEHLGGIVSAASAGDAHTRWETALPCRRRPANRRCPGRITVVRGDAEQPIGWQCSHCGDDGTISNWAASIYDLRRQQLTAAQPRRDIPIDADTAATLRTLPFLDNNCQRAVFAICAHGGELHLTMTAAELDDLIDALAAESNHEPHRRRQRQLDTAYDTLTAATDTPRW
>NZ_CP040250|1610556:1690873|1651795_1652473_+|WP_046184162.1|DBSCAN-SWA
MSAEQRHQHRRTRLIDAAIELIGTRGVAATTVTAVCAESRVTSRYFYQHFSDRDALLRAVYQQLYATFQDVIVQAIPDAGAPPDVLAYAPIRALVNMIEDDPRLARILFVESATEPLLRELRSQLMAGFADLVLREARLHLDIADSAVGVAHLASTLGVGGLFEVLRRWLDGELDFSTDELVQHCAGFLGSLGTYVLLQNIGEAPVPESGASANALSARGHARRC
>NZ_CP040250|1610556:1690873|1653302_1654139_+|WP_007168393.1|DBSCAN-SWA
MRLLPFGNPPRRSDRADAVITGAGSGIGRAFAVELARRGGRVVCADIDGIRAKETADLISKLGGHGIGVVCDVSDEHQVRDLADSAEKWFGGAPGLVINNAGIGAGGNVVGATSTSDWSATLSVNLWGVIHGCEVFVPRLRERGFGGLINVASAASFGAAPRMAAYNVSKAGVLALSETLAAELSGTGVTVTVLCPTFVKTNIVDNPRIEESAATLAANLMKWTGVSPESVARTTLDAHDRGQLYVLPQLDAKILWQLKRTMPGTFTHAMGLIQRITR
>NZ_CP040250|1610556:1690873|1613586_1614660_+|WP_019732397.1|DBSCAN-SWA
MTQDTSASRPLTSDVTGSDAAGRTEQSIPARPADAGAALAGGCPVSPLGYEAPPSPLGPDSLTWKYFGDWRGMLQGPWAGSMQNMHPQLGAAVLDHSTFFRERWPRLLRSLYPIGGVVFDGDRAPITGAEVRDYHTDIKGVDEQGRRYHALNPDVFYWAHSTFFVGTIHVAERFCGGITEEQKRQLFDEHVQWYRMYGMSMRPVPKSWEEFQEYWDHMCRNVLENNEAARAVLDLTELPKPPFAQWIPNRLWAAQRKLLAPFFVWVTVGLYDPPVRELMGYRWSARDEWLHRRFGDLVRIVFALVPSRFRKHPRARAGLDRASGRIPLDAPLVQTPARNLPPEDERGNPKHYCPMVS
>NZ_CP040250|1610556:1690873|1667130_1668717_-|WP_062887208.1|transposase|DBSCAN-SWA
MRTRVEQFAAIRRDRRVEGLSIRALADKYRVHRRTVRQALDSAVPPPRKTGPRAAPRLEPFKAAIDEMLRSDLDAPKKQRHTARRVLARLVDEHDAAGLSYSTVRDHIRKRRPQIAAEAGRALEAGFVPQTYRPGAEAEVDFHDLWVMLAGVKTKTALFTMRLSFSGRAAHRAFATQGQEAFLEGHVYGFDRLGGVPVDKIRYDNLNSAVKQVLFGRSRQENERWIAFRSHYGFEAWYCQPGHDGSHEKGGVEGEGGRFRRNHCVPMPVVDSIDELNAFLAAADDADDRRRIANRANSVGQDWETERQFLQPVADQGFETALTLTPRVDRYAQIMVRCNQYSVPARFIGHRVRVKLSASHVTVYDRTTVVARHPRAVGKGTKVLDLDHYLEILARKPGALPGATALAQARAAKLFTAEHDAWWAAARRVHGDAGGTRVLVEVLLLHRHLDRADVLAGISAALSVGSVNADVVALEARRAAEQRAGLGSPPGGGEGAQVLRLAEHRLIADERPLPSVAPYDTLLGQQSS
>NZ_CP040250|1610556:1690873|1689640_1690873_-|WP_011725525.1|transposase|DBSCAN-SWA
MALDQSALLEVLDALRTADAGERITQAAETIYQALIDAELTAFIGASPHERTETRSNQRNGSRPRTLSTVAGDLELRIPKLRTGSFFPALLERRRRVDQCLFAVVMEAYLHGTSTRKVDDLVKALGTDTGISKSEVSRICKDLDTEVAAFRDRPLGDQRFPYVFLDATYCKARVNHRVVSQAVVIATGVAADGRREVLGFEVGDSEDGAFWTAFLRSLKSRGLAGVQLVISDAHAGLRSAIDAVLIGAAWQRCRVHFLRNVLAQVPKGSAEMVAAAIRTVFAQPDAEHVREQLDTIAGMLGRQFPKVETMLREAAADITAFADFPVAHWKKIWSTNPLERLNKEIKRRTDVVGVFPNPAALLRLAGSVLVEAHDEWQVADKRYLSETSLALLDVSDQSAETIAPTAALTA
>NZ_CP040250|1610556:1690873|1631305_1632376_-|WP_132160400.1|DBSCAN-SWA
MTGGTQFEGQAYVLSPVGLADSAPAGSYAFRNRFDITSNSRFNVSDGTYILSDAQEYVCLTSTLGSKTIKNCTSLALWGSAYADFDTALIAGRKWRQIATWIFAQLAIACDFGDDDEENLNPLDNVPLHIRYSVGISDDDRAYRDRVGLLVFPVHPREPRFVYFAYEAVGLSGLGDLPNLITKAQHQHSTPWPEQLRLAWDLVHAGLGDPNPEAKYILTVTAVEALIPYREEHAHLSGLLDALKPIADGLAQFDEDTKEEVKKLLQNNKMNSVRRYGLQLADRLPGTYDGLAPKKYFDKAYGTRSDLAHGNLRNKANLTKSALIHQYDELRRFVIDILDSWAANPNFASPPKAAGK
>NZ_CP040250|1610556:1690873|1612903_1613518_-|WP_023861897.1|DBSCAN-SWA
MQTGQRRGRWTGVPLESRLALRRDNLINAGVQLLGGSGGPALTVRAVCRKAALTERYFYESFTDRDEFVRAVYDDVCTRAMNTLTSATTPREAVERFVELMVDDPVRGRVLLLAPAVEPVLTRSGAEWMPNFIDLLQRKLSRIGDAVLQKMIATSLVGGLSSLFTAYLHGQLGATRKQFIDYCTNMLYITAAPYVSAGELGKSQ
>NZ_CP040250|1610556:1690873|1627943_1628738_+|WP_009979999.1|DBSCAN-SWA
MTTAAKPVAPSSAAPLAADLDAALRRLKLATVRRNAAEVLQVAKTQRWTPEEILRTLVEAEIAARDASNTANRLKAAAFPVTKTLDGFDVTGSSITAATFDYLSSLEWIRAQQNLAVIGPPGTGKSHLLIGCGHAAVHAGFKVRYFTAADLIEVLYRGLADNTVGKIIDTLLRADLVILDEIGFAPLDDTGTQLLFRLVAAGYERRSLAIASHWPFEQWGRFLPEHTTAASILDRLLHHASIVVTSGESYRMRHADHKKGAAKN
>NZ_CP040250|1610556:1690873|1661607_1663224_+|WP_085981616.1|DBSCAN-SWA
MQDIPLTVASIVRHATSIHADSQVVTPTGSGYRTTTYGALKRRISQLANALRSLGITDDQRVATFQWSNQEHLEAYCAVPSMGAVLHTLNLRLTAEQLGYISDHADDKVIIADVSVAPLLAKALPTMSSVHTVIAAGDGDLEPLLASGKNVLRYEDLLADQDGEFDWPELDERSAAAMCYTSGTTGNPKGVVYSHRSTYLHSLTGCTPNVLSIGEEDRVLAIVPMFHANAWGLIYSALMCGADLVLPDRYLQAAPLVAIIEDTQPTVAGAVPTIWNDVQHFLESEPEHDISSLRLVACGGSAVPRSLMEHFESEFGVPILQAWGMTETSPLATVARAPKGTNGERQWELRACQGRPVCGVEIRLRGDDGRTLPWDGRSIGEIQARGPWVTGSYFGDNDSDKLDEGWLRTGDVGRIDQHGYLTLTDRVKDVIKSGGEWISSVDLENALVAHPAVHEAVVIGVPDEKWQERPLALIVTKTETSLDINELRVFLDGAVAKWWIPERWAFIAEVPRTSVGKYDKKLLRARHGAGEYQVVYCG
>NZ_CP040250|1610556:1690873|1649289_1649481_+|WP_074021704.1|DBSCAN-SWA
MKITVDRDRCSSIGMCEGLAPDFFEVSNDGKLHILNPGPPECHRALIEDAVASCPTGALALHD
>NZ_CP040250|1610556:1690873|1614936_1615338_-|WP_003877217.1|DBSCAN-SWA
MHADSSAGRLPDDQVRLVVEVFRMLADATRVQVLWSLTDREMSVNELAEHVGKPAPSVSQHLAKLRMARLVRTRREGTTIFYSLENEHVRQLVIDAVFNAEHAGPGVPGHHRGEGGLKSVAASSRHRPRGAAR
>NZ_CP040250|1610556:1690873|1649613_1650630_+|WP_033717470.1|DBSCAN-SWA
MSTFGLSVLAPDLAAMKVTATAADQAGFDAVWASEFYTRSGSISMAAMATSTDRCRIGSSILYGVGRSPLVLATEARDLDELSGGRIVLGIGNGTKRMMSNWHSVADTSAPALRVEELVPLIRRIWNLHEGPVRHEGRFYQMNLIPSGPVDPPARDIPIITAAVRPRMCEAAGRVADGLAGHPLFTTAYVEEVVRPAVAKGAARTGRDPDDVEIVSMVMCSIHDDPEIARREVAQQIAFYASVRTYQPLLDFCGFAKQGAVIREAFARGDFAAMFDAVTDDMIDVMGVAGTASEVRAGLRRYEGVLDHIMLYPPSVGIAPERVGQNLGEMIKHCAPGQ
>NZ_CP040250|1610556:1690873|1684276_1685020_-|WP_007168420.1|DBSCAN-SWA
MGPFADPRAGADDLTAKARIRNAAMDLFAEFGEDRTSMRNIASRAGVTVGLVVHHFKTKDGIRRAVEQLVVDYFAQTIAQVPVDGTPRQVATARDVAVKEMLESNPAVVNYLRRALLDPAGSKGQLLQRLTELTRTELIKARDAGIANAERSGSTQIIDIMVRQLGQLFLQPMIDTMWDQVSRPDESDDDKPTLHVAVRSSGPAPSARHRNTSACAAGEVVWRPAGPLPAAGPRPSTGAEHCHATSR
>NZ_CP040250|1610556:1690873|1642921_1643362_+|WP_007168380.1|DBSCAN-SWA
MEFAQFNQQIAKELQNAAATTGGLSKYLDFRHTEFAAGRLVVQMDARDDLLTPFGNLHGGCLSAMVDHCLGVVFYPVIPAGSWVATTEFKLNLLQPVSSGVCVAVTEIIALGKRSGVARIDITNDGRAVCAAQGTVTVVSPRGNSS
>NZ_CP040250|1610556:1690873|1636333_1637446_+|WP_094494180.1|transposase|DBSCAN-SWA
MILRGTDQSHSSKGINAMTIAHDIDLSAVLAERLTTTHPDVLRELLAAFIHALMGAEADAVCGAGYGQRSSERTNSRNGYRHREFDTRAGTLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITSLSKSQVSVMAKELDAAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIATGVNAEGYREILGIDVTTAEDGAGWLTFLRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVRTLLHSVFDQPDAGSVAAQYDRIIDALADKLPKVADHLEDARADLLAFTAFPKQIWRQIWSNNPLSVNRLSGDTVRAAA
>NZ_CP040250|1610556:1690873|1626366_1627947_+|WP_011724852.1|transposase|DBSCAN-SWA
MSFPGAEGLGGDGDSANCHLITAQGALLKSARERMNIISAYHQVGSYRGAAELCGTTHKTVKRVIERAEAGGAPPREPRPRNLDAFTDLVATRVEKSHGKMSAKRMLPIARAAGYQGSARNFRRLVAEQKVLWRNANRHQRRPAVWSPGDYLVMDWAEAAPGLMVFCAVLAYSRWRFVRFAADEKASTTLAMIAEALEAIGGVPAKILADRMGCLKGGVVANVVVPTPDYVRFASHYGFVPDFCHGADPQSKGIVENLCGYAQDDLAVPLLTEAALAGEQVDLRALNAQAQLWCAEVNATVHSEICAVPNDRLVDERTVLRELPSLRPTIGSGSVRRKVDGLSCIRYGSARYSVPQRLVGATVAVVVDHGALILLEPATGVIVAEHELVSPGEVSILDEHYDGPRPAPSRGPRPKTQAEKRFCALGTEAQQFLVGAAAIGNTRLKSELDILLGLGAAHGEQALIDALRRAVAFRRFRAADVRSILAAGAGTPQPRPAGDALVLDLPTVETRSLEAYKINTTDGTAS
>NZ_CP040250|1610556:1690873|1611696_1612719_-|WP_003875819.1|DBSCAN-SWA
MSAELTNLQLLQELEPFVEKYLNRHESMHKNWNPHDYIPWSDGKNFYALGGQDWEPGQSKLSDVAQVAMVQNLMTEDNLPSYHREIAMNFGMDGPWGQWVNRWTAEENRHGIALRDYLVVTRAVDPVELEKLRIEVVNRGFSPGQNHQVREDLFAESLFDSVIYVTFQELATRISHRNTGKACNETIADQMLAKISADENLHMIFYRDVSEAGFAIAPNQAMKSLHKVLRNFQMPGYQVPEFRRKAVMIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAAALRDDLALLIKELETTCDKFEISKRRQLEREARTGKRTTALELHTTAGTLTMSRR
>NZ_CP040250|1610556:1690873|1658318_1659287_+|WP_007168397.1|DBSCAN-SWA
MTTLYSEQHPSTASYLIATSARGILRPLTQALPSNQYGLAVMDRVLRAALIASRPRRGLRVEQVDTVFAGDRVRGDWIVAPDVDPDGPPILYIHGGAFSMCSPQTHRGLLGELSAASLRPVFAVRYRLAPRYPYPAAADDALRAYRWLTGSEESASNRTVAIAGDSAGGQLAVATSLGALAHRSPPPDGMLLMSPVVDLTCQLAMARETRRRDPFASARSATRALSLYVGDAHPTDPRVNVLAADLTGLPPTLIQVGGREMLLDDSRQLAERMRAAGASVRLQVFRGQIHVFQALFRLLPEARHALHLSGAFLTDRAEDTFP
>NZ_CP040250|1610556:1690873|1659464_1660922_+|WP_033712835.1|DBSCAN-SWA
MVNPLHAPVDKARERLSSVILIPAPQRVDDGLRRWSRRWPVRELAAPPAGSGLRPVLGDAGLPLVGHTLDYIRFGSDLGRERYERFGSVSWMGAFGTKMAVIAGPQATQEALTTNAKAFSQDGWAFLIDAFFHRGLMLMSFDEHLMHRRIMQEAFTRPRLAGYVTQVTPCVRATLPTWPTGPSVRMYPLLKNLTLDIATDVFMGGRGKDSSDAINQAFVATVRAASSLVRAPLPGTRYRAGIRGRRVLEEYFARHLPAARAGNSNDLFAALCHASTEDGQRFSDSDVINHMIFLMMAAHDTSTITTTAVTYYLAKHPEWQDRVRAESDALGDRSPEIDDLEALRSLDLVIKESMRLVAPVPLVMRKTVQDTAIDGHYIPRDTLVAITPAVNHFVREVWHNPDRFDPLRFDDPRREDQAHRFAWLPFGGGAHKCIGMHFGTLEVKAILHQMLRTFTFGLDTDYRIRWDNTSLPIPVDGLPITLRRR
>NZ_CP040250|1610556:1690873|1642227_1642872_+|WP_007168379.1|DBSCAN-SWA
MTKKSLRWGTAPPTTRDVARDLLLDAAEACLEGKGLPGTTMEDIARQAGVSRATVYRYFPSRESVVSGVILRAAERYLDRMRRRIAVHRDLGTAILDFVEVTVRAAHREPTIGLLFGSDEELAGVGLAKGTSVALFELVAEFLRPVFAAHWDQLEPGVSVDDAAEWILRTVLSLLSVRGPRHRSPEGLDAFLRRFLLPALLTNTQPCVDATSAE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019732805.1|1610556_1611690_-|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_003875819.1|1611696_1612719_-	acyl-ACP desaturase	NA	NA	NA	NA
WP_023861897.1|1612903_1613518_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_019732397.1|1613586_1614660_+	DUF2236 domain-containing protein	NA	NA	NA	NA
WP_011723747.1|1614676_1614880_-	hypothetical protein	NA	NA	NA	NA
WP_003877217.1|1614936_1615338_-	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	4.6e-07	31.9
WP_019732396.1|1615381_1615915_-	nucleoside deaminase	S4VYZ2	Pandoravirus	5.6e-16	39.3
WP_019732395.1|1615969_1616866_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_132160402.1|1617910_1619938_+	hypothetical protein	NA	NA	NA	NA
WP_062887574.1|1621396_1621735_-	DUF3024 domain-containing protein	NA	NA	NA	NA
WP_062895398.1|1621739_1622318_-	hypothetical protein	NA	NA	NA	NA
WP_062895396.1|1622363_1623155_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	5.0e-29	34.9
WP_011724852.1|1626366_1627947_+|transposase	IS21 family transposase	NA	NA	NA	NA
WP_009979999.1|1627943_1628738_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-30	33.9
WP_132160400.1|1631305_1632376_-	hypothetical protein	NA	NA	NA	NA
WP_057969464.1|1635235_1636129_+	hypothetical protein	NA	NA	NA	NA
WP_094494180.1|1636333_1637446_+|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.0e-67	44.2
1637399:1637458	attL	NA	NA	NA	NA
WP_007172498.1|1637514_1638564_+|integrase	tyrosine-type recombinase/integrase	A0A166YH27	Gordonia_phage	3.8e-08	27.1
WP_007168379.1|1642227_1642872_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007168380.1|1642921_1643362_+	PaaI family thioesterase	NA	NA	NA	NA
WP_007168381.1|1643414_1644311_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_019732564.1|1644358_1644574_+	hypothetical protein	NA	NA	NA	NA
WP_007168383.1|1645103_1646552_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.4e-55	35.6
WP_085981614.1|1647259_1647889_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007168386.1|1647976_1649278_+	cytochrome P450	NA	NA	NA	NA
WP_074021704.1|1649289_1649481_+	ferredoxin	NA	NA	NA	NA
WP_033717470.1|1649613_1650630_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_033712834.1|1650822_1651692_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_046184162.1|1651795_1652473_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_023900852.1|1652499_1653168_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007168393.1|1653302_1654139_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_007168394.1|1654157_1655081_+	hypothetical protein	NA	NA	NA	NA
WP_007168395.1|1655077_1656724_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_007168396.1|1656798_1658322_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_007168397.1|1658318_1659287_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_033712835.1|1659464_1660922_+	cytochrome P450	NA	NA	NA	NA
WP_007168400.1|1660918_1661575_+	transglutaminase domain-containing protein	NA	NA	NA	NA
WP_085981616.1|1661607_1663224_+	long-chain fatty acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.6e-26	24.5
WP_033712837.1|1663272_1664415_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_033711234.1|1664801_1665128_-	hypothetical protein	NA	NA	NA	NA
WP_062887574.1|1665377_1665716_-	DUF3024 domain-containing protein	NA	NA	NA	NA
WP_062887208.1|1667130_1668717_-|transposase	IS21 family transposase	NA	NA	NA	NA
WP_138017752.1|1670947_1671079_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_007168405.1|1671917_1672790_+	dehydrogenase	NA	NA	NA	NA
WP_007168406.1|1672942_1673218_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_007168407.1|1673217_1673610_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_138017753.1|1678679_1680422_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_007168415.1|1680443_1680980_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_080576326.1|1681381_1682071_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_109233510.1|1682155_1683457_-|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	5.0e-34	28.4
WP_007168419.1|1683666_1683975_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_007168420.1|1684276_1685020_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_007168421.1|1685117_1685969_+	CoA transferase	NA	NA	NA	NA
WP_019732177.1|1685965_1687141_+	thiolase family protein	NA	NA	NA	NA
WP_007168424.1|1687150_1688827_+	long-chain-fatty-acid--CoA ligase	NA	NA	NA	NA
WP_138017754.1|1688823_1689651_+	2,3-dehydroadipyl-CoA hydratase	NA	NA	NA	NA
WP_011725525.1|1689640_1690873_-|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
1702152:1702266	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP040250|1693950:1731208|DBSCAN-SWA
GATGCCCTCCCCGGGGCGGCCGTCGGTGGCCTGGCGGCAGGACAGGGTCCGGTTCTGGGCGGGGATCGCTGCCGGAGCGATGACCGAGGACGCCGCTACCGAAGCGGGCGTGTCTTCGCCGGTCGGGTTCCGCTGGTTCCGCCATGCTGGCGGCGTGAATCCACGCTTGCCAGAAACTGTTTCGGGCTGCTACCTATCCTCGAATGAGCGCGAAGACATCGCTTTATGGCGTGCCCATGGTGCCGGAGTGCGCGAGATAGCCAGGAGGCTGCGCAGGGCGCCGTCGACCATCTCGCGTGAGCTGCGCCGTAACGCCTCGACGCGCACGTATCGGCTCGACTACAAGGCCTCGGTCGCGCAGTGGCATGCCGAAAGGCGGGCGAGGCGCCCGAAGACGGCCAAGCTGGTCGGCAACGACCGGCTGCGCCAGTACGTCCAGGACAAGCTCTCCGGTGTCGTTCGTGGCGCTTACGGGCAGATCATGGCTGGTCCGGCCGCGACGCCGTGGAAGGGACGCAACAAGCCGCACCGAGGGGATCGGGCCTGGGTGACAGCATGGAGTCCTGAGCAGATCGCCCATCGGATCAAGCTTGACTTCCCTGATGATGAATCCATGCGGATCAGCCACGAGGCCATCTACCAAGCGCTCTACGTGCAAAGCCGCGGTGCGCTCAAGCGGGACTTAATCACCTGCCTGCGCCGGGGTCGGGCATTGCGGGTGCCGCGGGCACGGTCTCGGCAGAAAGCGTGGGCGCACGTCACGCCGGAGACGTTGATCAGCGCTCGGCCGCCGGAGGTCGCTGATCGCGCGGTCCCGGGACACTGGGAGGGAGATCTGCTGATCGGGTTGCAGCGCAGCGCGATCGGCACGCTGGTCGAGCGCAGCAGTCGGTTCACGATGTTGATCCATCTTCCGCGGGAGGCCGGATACGGGCTGATTCCGCGGACCAAGAACGGGCCGGCTCTGGCCGGCTACGGCGCCCTCACGATGGCCAACGCCCTAGCGCAGACGATCACCTCGCTGCCCGAGGAACTGCGCCGGTCGCTGACCTGGGACCGGGGAAAGGAACTGTCGGCGCATGCCCAGTTCTCGATCGCCTCCGGGGTCAAGGTGTACTTCGCCGACCCGAAGAGTCCGTGGCAGCGTGGCACGAATGAGAACACCAATGGCCTGTTGCGCCAATGCTTTCCGAAGGGCACCGACCTATCCCGGTGGAACGCCGACGACATCGCGGCGATCGCTCACACCCTCAACACCCGACCACGCAAGACCCTCGGATGGCGCACCCCGGCCGAAGCGTTCAACGAACACCTACACTCACTTCAGCAAGCCGGTGTTGCAACGACCGATTGAATCCAGCCTGGTCACCTGCCGCAAGTTCGCCCCGGCCGCCCGCAACTACGCGGTCGCCCGGCTGGCGGCCGACGTGGGACTGCGCATCAACGAGGCGCGGATGCTCGACCTCGACGATGTGCGGTGGGAGCTGGGGCGGTTCGGCAAGCTGAACGTCCGTCACGGCAAGGGATCACGCCGCAAAGGCCCCAAACCGCGACTGGTGCCGCTGATCAACGGCGCCGACCGCAGCCTGAGATGGTTCATCGAAGACGTGCTTGGACTGTTCGATATCGACCCGAATAGCCATGCCGCGCCACTGTTTCCGTCCGAACGCAAGAACATCGACGGGACGTGCATGCGCGCGACAGCTGACGTCTATCGCCGATCGTTGGCGGAGGCGGCGGACCGGCATCTGCCTGCGTGGTCGGGGAAGCTGACCCCGCATGTGCTGCGGCACTTCTGCGCGTCCCAGCTTTACCTCGGCGGAATGAACCTGTTCGCCATCCAGGAATTATGTGGTCACGCCTGGACGGCCACGACGGCTCGATATATCCACGTCCACGCCACCCACGTCGAAGATGCCTGGGTCACAGCACAACGTAACAACACGAAGTAACTGCACCTACGAACTTAAGGATTGGCTCAATGAAGTGGAATCTACGCCTGACCGCGGCCAACCGCGGCATTTGGAAGGCCAGCGAACTCCAACGGATGCTGGCCGAGCGCGGCCTGGTGATCAGCGCCGGCAAGATGTCGGGCTTGTGGTCGGGCAACCCCAACGCCATCAAGCTCCACGATCTCGATGTATTCTGCGCCGTGCTCGACTGCGCCATCGACGAACTGCTGATCCCCGAGCCCGAAACCGTGGCCGCACCCACGCCGAAGGGTAGCGAGGAGGCCGCCGCTGCGGCCGGTGAGGCACGTCCCGTCACCCCGCGCGCTCGGACGGGAAGGTCGCTGCCGCCGCGATGAATTGCCTGCAATGCGGAGCCGAACTGCCAGCCAACGGTCGCCGCGACCAAAAATACTGCGGCAGAAGCTGTTCAAAAAAAGCGCACTACTATCGCGGAAAGGCGGGACTGCCTGCTCGCCCGCCCCGGCGGCATCCAGCCTTGGAATCCGACGACCCCGTGCTCGTGGCCGCTGCGGTATACGCCCGGGAACGCGCTGCCGCCCACGATTGGTGCGGTGAGACCACAAACCGATGCCTCGACGCCCTGGTCACCCTTCTGGCCGGTCGGCCCCCCGGTGATCGCGTGCCGCTCAAAGAGGTTCGAACACGGCCGCATCGGCTCGCGTCCCGTCGCAGGCTTGTCGAAATCCTCTCCCACTTCGACCTGCTGACAGACGACACCGAACCTCCGATCCGTGCCTGGATCGACCGCGTCACCGCGGAACTTCCGCCAGGGTTCGCCGAGCCGTCGCACCACTGGCTCCTTACCCTGTTGGTCGGCGGCGCACGTGCTCGCCCACGATCGCCCAGGACCCTCTACAGCTACTTCGGCGCGGTCAGGCCCCTTCTCGCGCACTGGTCCACCTCCTACGACCATCTCAGGGAGGTCACCAGGGCCGACGTCGACGCGACGCTGCGGCCGTTTCAGGGAAACCAGTGCCACAATCTGATCAAGGCGCTGCGGTCGCTGTTCCGGCACGCCAAGAAGAATGGTCTGGTCTTCAGCAACCCAACAGCGGGTTTGAAGAGCCAACCAGTAGACCAAGACCTCGTGCCCATCACCGATGATGAGGTGCGCTCGATCGAACAGCTCGCGAGCGAACCGCGTGCACGCCTAGTTGTGGCATTGAGCGTCGAACATGCCTGCCGCACAAGCGTTATACGCAAACTGGTGCTCGACGACATTGACCTGCCGAACCGGCGGATCACCCTTGCTGGACAACCAACGGCTCGGCGAGCTCACCCACAGAGCGCTGATCACATGGCTCGACCACCGCCGGGACAGATGGCCCCACACTCCGAACCGGCACGTTCTACTCACGACGAAAACTGCATTGCGCACAACGCCGGTGAGTCAAACATCGGTGAAACAATCGTTGAGCGACAATGGGTTCACGATCGAACGCATCCGTGCCGACCGAATCCTTCACGAAGCGCTGACCGCAGGCCCCGACCTGCTGCATCTGTCTCTCTCGTTTTCGGCATCTCCCACAACACCGCGCGGCGCTACACCACCGCGAGGGAGTATCCGAAATTCGGTGTAAGTGGCCCGACACGCCGGGTGTGAGCCTGGCGGGGAAGGTCCACGATGACCGAAACGATGAGGGCTGTGACAGCAACAGCCGATGTCCACGATGATGAAGTGATGGTCAGCTCTCCGACACCGGAGGAGCTGGCGACGGCCCGCGAGCTGGTGCGGGCGGCCCAGGCCCGCGGGGTGTCGTTCGCCGATACCGCTGACGGGGTGCTTAAGGCGCTGACCAAGACGGTGGTCGAGACCGCGCTGGAAGAGGAGCTCGCCGATCACCTCGGCTATGACAAGCACGATCCGGCCGGGCGGGGGGCGCCGAATTCACGCAACGGCACCCGCACCAAAACCGTGTTGACCGACACGGTCGGACCGGTCGAGATCGCCGTGCCCCGCGACCGCGGCGGCAGCTTCGAGCCCCAGATCGTCAAGAAAGCATCAACACCGGTTGACCCGGGTCGATGAGATCGTGTTGTCGTTGTATGCCAAGGGATTGACCACCGGGGAGATCGCCGCCCACTTCGACGAGCTCTACGACGCCAAGATCTCCCCGGACACCATCAGCAGGATCACCGACAAGGTCCTGGCCGACATGGCGGAGTGGACCGCGCGGCCGCTCCGTCTACGCCGCAATCTTCATCGACGCGCTGAGCGTGAAAGTGCGCGACGGTCAGGTCGCCAACCGACCGTTCTACGCCGCGATCGGGGTCGATCTGGCCGGGCACAAGGACGTGCTCGGACTGTGGGCCGGCGACGGCGCCGGGGAATCAGCCAAGTTCTGGTTCGCCGTATTGACCGACCTGCGCAACAGAGGCGTCACCGACACGTTCTTCTTGATCTGCGACGGACTTAAGGGGCTGCCCGACGTTGTCGGTGAGGTGTGGCCGGCCACCATCGTGCAGGCCTGCACCGTGCATCTGATCCGCAACAGCTTCCGCTACGTACCGCGCCAGCACTGGGACGCCCTGCGCCGCGATCTCAAACCGATCTACACCGCCCCGACAGCGGCGGCCGCAGAAGCGGCGCTCGAGGCGCTCGCCGACCGCTGGGGCAGCCGATATCCGGCCCTGATCCGACTGTGGCAGTCGTGTTGGAATGAGTTCATCCCGTTCCTGGATTACGACACCGAGATTCGGCGGGTTCTGTGTAGCACCAACGCAATTGTTATCTGGAGTCCTCCGGGCGGTGTCCTTGATGTCCGACACGAGGCGTTCAGATCCCAGGTTCTGCGTGGTGGACGTGATTATCTGCAGTCGTCCAGGAGGCAAGAACCTGCGGAGGGACGATGCAGATTGCGGTCAAGTCCAGGGACGTGGTGTACGACGTCGTCGTGTGATTCTTCGACTTGGTGGTTTAGGCGGTCAGTGCCGCCGGGGTGTCCTCCTGTTCTGTTGATGGCGTGTGGTCGGCGCGGGATTTGCTGAGGACGTCGAGGCCGAGGTAGCGGCGGGATTCGGCCCATTCGTCGTGTTGTTCGGCCAGCACCGCGCCGACGAGGCGGATTAGGGCGTTGCGGTCGGGGAAGATTCCGACGACGTCGGTGCGCCGGCGGATTTCCTTGTTGAGTCGTTCTTTTATCCGGCCCTCGGGGGCGGGTCAACCCGTCGGGGTGGGATGTTCATCGATCGAGGCGCTGGAGGTGGTCGGTAAGGGCGTGGGCGACGCGGTCGTGGCGGGCGGCTTCGTCGGTCCAGCCGCGGCACTCGGCGTCGGTTCTGAGGGCCTGGACGTCGGCGAGTTGGTCGGTGAGCGTGTCGCGGAATTCGGGGGGCGGTGACGTAGTTGTCGCAGGTTTCGCAGATGTTGGCATAAGGGCACGCGCCCGCGGATTCGTGGCGAGCGCAGTATCCGTGTGCAACGCGGGTTTTCAGCATTTCACTGTGCAGCCAGCCGACCTTGTCGGGCAGGATCGGTTTGCCGACCGGGGTGAGGGTGAACTGGCGGCGCATCTTGCCCATCGCTTCGTCGTAGGCCGCGCGCAGGGTGGGCGAGGCCAGGGTGGCGTAGCGGATCGTCATTTGTGGAGTGACGTGCCCGAGTAAGGACATCAAGGCCTGCAGACTCATCCCGGCGTTGGCGAGTTCGGTGGCCCAGGTGTGGCGCAACTGATGTGGAGTGACCATCAGGACGCCGCCGTCGGGACGGTGCAACCCGGCGGATTCAGCGGCGGTGAGCAGCCCGTTGCGCAGCCGGGTGTAGCCCAGGCGGCGTCCGTGCCGGGTGAACAGAAAGTCGGTGAGCACGCCGGTGCGTGGGTGCGGCAGCGGCCGGTGCGTGCCGCGGAGGGCGACCCACTCGTCGAGCGCGGCGAGGGTCGCGGCGGAGAGCGGGACCATGCGTTCGGTGGCGAGCTTGCCCAGTGGCACCTTCAGCCAGGTTCCGGCCGGTCCGTAGTCGATGATGCTGCCCAGTTCGAGGTCGAGCAGTTCCCCCGCCCGCAGGCCGGCACCACGCAGCACGGTCAGGCCGATGCGGGCGAACGGATCCTGCAGGTGGGCAACGGCGTTCATCACTGCCGCGTCCACATCGGGTGCTAGCGCGCGTGGCAACGGCTGGTCGAGTTTGGGGACGTCGGCGGCGAATACCAACCGCCGTGGTGGGGCCTGCGCCCAGCCCCAGGCGGTGATGTCGTCGAGCAGGTTGCGCAGACTGAGCACTGCCGACTGGGCCACCGCGGCCGAGACGGTGCGCCCGGCGCCCGCGGCGGCGCGCTGACCACGCCAGCCCCGGGTGCGATTCCATTTCAGGTAGCCCTCGATGCAGCTCCGGTCGAGTTCACGCAGGCTGATGACGTCGGGATGGTGAGCGGTGAGGTATTCGGCGAAGGGCAGCAGGTCGTTGATCAGCGACTCGACCGATTTGGGCCGCAGCACCGCCGCGCGCACGCCGATGTAGCGCAGCAACGTCTGACGGATCGGGTCGGGCATCTCCACCTCGGTGAAGCGCTGCTCGAGGCTACGGGCCCACCGCCGGCGTTTCGGCGCGGTGTCGATGACCGCGGTCTCGAACAACAGCTGCCGCAGGCTGGCCAGCCGCCCCCTGTATGCCCGCCGCGACGATGGCGGCACCACGGTACGTGACAGCGCGGCGTCGAAGTCGTCGAGCGCGTCGCCGGTCAGGTCGGCGACCATTCCGCCGTGGTGTGCCAGCACTACCGCCAGACATTCGCCGAGGACCGTCTCGACCCAGGAACTCCTCCAGCCCAACCGAATTCCCGCATTCCGCAACGCGGCGAATCCGCTCGGATCCCGGTCCTCCACTGCGCGGCCCAGCCCGGTCAACTGTTTGACCGCGGCCAGCTCGACGTCCAGCCGTAACCGGCCGGTGCCGATCGTGTGACAGATCAGCGGCCACGCCCCGGTGTCCCGTATCTCGGCGATCCGCTCGGCTGCCGGCAGCGTCATCCAGGCGTGCAGGTCGCGGTGGCGTGCGGTGAAGTCGCGAGCGATCCGAATCCGGTCGCGTACCGCCCGCCCGCTCAAACCCAGGGTGGCGACGTGGTCGAGATAATCCGCCACCACCTCGTCGGCGCCTACGGGTTGGCCGACCAACACCGTGGTCACTGCCGGGCTCCGGCCAACGTCGCACGAGCAGCACCGTATTCGGCGGCGAGCTGCTCGATCGACAAATGCACGTAGCGGGCCGTGGTCTCCGGCGAGACATGCCCCATCAACGCCCGCAACGCCAGCAGATCGATTCCGGCCGCCGACAATTCGGTGCCGTAGGTATGCCGTAAACGGTGCGGGCGGACTCTTGTGGCGCCAGAGGTCTCCCGGTGCCGACGGAACAGGCTGCGCAGCCCGGCCTCGCTGACCGGTGCACCGGTCGTCGGGCCGCGCAGCACTACGAAGCACTGCGGCGTCGCCAACCCCGGCGGCCGCTCCCATCGCAGGTAGGCGGCGAGCTCGGTGAAGAACGCCGCATCGACCGGGACATGACGTTCCTTGCCGCCCTTGCCGATCACCCGAAGCCGGCGCCGGCCCATATCGACGTCGGCGAGCAGCAGGCCACGCGCCTCGGCCGAACGCAGCCCTCCGAGTAGCATCACCAGCACCATCGCCCGGTCCCGGTGCGTTGCCAGTGTCGCCAGGAACGCGTCGACATCGTTGGTGGACAACGATTCCGGAAGACGCTGCGGCTGACGCACCAACCTACCGCCACTGCGTGCACGCCCGGGACCCAGATGACCGAGCAACCCCGCTGCGACTGGCGCAGCCCCTGTCCCCCGCCGCGGCGACGGCACCGGATTGTCGGTGCAGACACCGGTCATCACCAGATACTCGAATAACGCGCGCACTGCCGCGACCCGGCGGTTCACCGTCGAAGCTGCCGGCGGGGTCGACGAGCGGTGACCGCCGGTGGGCTGGTCCGTTCGGCGGACGCCTTGCCAGTCGATCCAGTCGAACACCAACGGCGCATCGACCGCGGCGAGCCCGACCGCTTGCTGGACGAGGAACCGGCTCAAATTGGCGACGTCGAATGCGTAGGCCCGCACCGTGGCCGCGCTGAACCCCCGTCCCGCCAAATGGTTGAGAAACGCGTTCACCGCGTCCTGCCCGTCCCAGTCGCCCTCCAGGACATATCCGCTGTCGCTCTTGAGTACCCGCATCGCCGCTCCGCCTTCCCCCACCGAGATGCAGACAGCATCCATCCGTGCTCAGCGCTTGTGCGTGAACCTCACGCTGCAGCCCGAACCGTGTCCCCGGAGAGCCGGTTAACGGATAGGGGTTGGTGCTCCAGATCTTTTTCCAGTGCAGGACAGGGAAATCGGCGAATGCGGTGATGTCGTCGGCGGCCTCGCGCAGCATCGTTTCGACCTTGGGCAGTTGGCGGCCGAGCATGCCGGCGATGGTGTCGAGTTGCTCTCGCACATGTTCGGCGTCGGGTTGGGCGAAGATGGTGCGGATCGCTGCGGCGACCATCTCGGCTGATCCTTTGGGCACCTGGGCGAGCACGTTGCGCAGGAAGTGCACCCGGCATCGTTGCCAAGATGCGCCGATGAGGATGGCCTCGATGGCGCTGCGCAACCCGGTGTGGGCATCAGAGATCACCAGCTGCACCCCGGACAGGCCGCGGGTTTTCAGTGAGCGCAGAAACGCCGTCCAAAACGCGCCGTCCTCGGAGTCACCGACGTCGAAGCCGAGCACTTCACGGCGTCCGTCAGCCGCGACACCGGTGGCGATGACGACCGCTTGGGAGACCACCCGATGGTTGACCCGAGCCTTGCAGTAAGTGGCGTCGAGGAACACATACGGGAAGTGCTGCTCGGATAGAGGCCGGTCCCGAAAGGCGCCTACCTCGGTGTCCAGATCGGCGCAAATCCGGGAGACCTCGCTTTTGGAGATGCCGGCGTCCGCGCCGAGGGCTTTAACCAAATCGTCGACTTTGCGGGTGGAGGTGCCGTGCAAATAGGCCTCCATCACCACCGCGAACAAGCACTGATCGACCCGGCGGCGCCGCTCCAGCAGCGCCGGGAAGAACGAGCCCGACCGAAGCTTGGGAATCCGCAACTCCAAATCGCCAGCGATCGTCGACAGTGTGCGCGGCCGAGACCCGTTGCGCTGGTTGGTTCGTGATGCGCTCCGTTCATGCGGACCGGCGCCGATCACCGCCGTCAGCTCCGCATCGATGAGTGCCTGATAAATCGTCTCGGCGGCCTGCTTGATCCGATCAGCGGCATCGGCATTGCGTAATGCGTCCAGCACCTCCAGCAAGGCAGACTGGTCCAGGGCCATCGCGATGTTCCTCTCGGTAGTGATCCTTGGTCGTTTCACCACAGAGACTCACGCGATGGCCCTCTACATCAGCACCGACACGCCGCCACTATTTACACCACGCCCCGGGACGTTCCCTCCGTGTCCGCGCGCGCATGTCAACAGCTCGCCATTTCGAAGGGGCCTGCATCCCCCGTGTTTGCCCGTTGTGATCGTGTTGACTCGGTAATCTTTCGACGATGGAGGAGGCGCTGCTGCGGCTGCTGCTCGCTCGTGATCCCATTCCGCCTGCCGTGCTGTCCTGGATCGTCACCGGAACCTGGCCGCACGAACTCACGCAGCCCCGCTATGACGTGTCTTTCCCGCACCTGAGCGGCCCCCAGCCCTTCTAAACGCCCATCGGCGCACAACGCCCCTGTCTGTCTGCCCCCGGGCAACACAGCATTCCCACTCGCCGGGGCCCACGCTGCTCGCCGTAGCGGCTGAAGACGACGTGCTGGGACCGTTTGGGCGGCCAGGCCCCAGCACGTGCCACTGCCTCATTCGTCGTTCCACCCCTTGCACACTCAGCTCCCCCCTTCCCTCTCGTCCCCGCCTTCTCCGACTACGCTTGCCCCACAACCGCTTTCTCGCCAATTCTCGCCATTTCCTCCTTTATCGATAACCACCCCACCGAATCGCCTGCCCCACACAGCAATTCACACCAACTCACCGACTTCCGCTATGGCACATTGGCACAAGGGGTGCAAGCATGGGCTGTGGCGAACCTTCGGTGCGCCACAGCCGGCCCCGGCGTGCGGGGTCGGTCACCGTGGACAGGGGTCGGTCGTTGCTTTCGATTTCCAAGCCGATGAAGCGGCATTCGGTGCGCTACTACAACGACACTGCGCGCGCGGCGATCTCGGCATCGGCCGATCGGCAACGCGCCGGCGGGGGGTTGGCCGAGTACTACTCCGAAGGCGAAACCCGCGCCCCGGTATGGGTGTGTGTGGGTGAGTCCGGCGATGCCGAAAAGGCTGCTGCGCTAGTCGGTTTGAGCGCTGCTGATCGTGCCGGCGGGCCCGCCGATCTCGACGTGGTGGCGCGCTGGCTCGATGAGGGAATCGCCCCCAACGGTGCCCAGGGCCGGGCATTTTCTGCGCGCTCAACCCACGGGTTCGATTTGACGTTTGGTGCCCCGAAAAGTGTGACGCTGCTGCGCGCTGTCAGCGGTGATGACGTACTAGCGAAAGCGGTTGTGGAGGCCCACAACCACGCCGTGCGCGAGGCGCTGGAGTACCTGTATGACCACGCCGGCTACACCCGCGTGCACAACCCGGACACCGGCAAAAAAGACCTCGTGCGGCTGCCGGGTTTAGTGATGGCGGCCTACCAACATGAGACGTCGCGCGACGGTGATCCGCACCTGCACACCCACGTGCTGTTGCCCAACACTCAGGCCCGTGGCGATGGCACGTTGGTGTCGGTCGACTCCAAATCGCTGCACCATGAAGCCAAGGCTGCCGGCATCATTTATCAGGCCACGTTGCGCCACCACCTGTTGCAGTCGGTGGGCTTGGAGTGGGGGCCGATCGACCCCCGTACCGGGATGGCGGAGATCGCCGGCGTGGATCGCGCCACGATCAAGTCATGGTCGCAGCGCTCGACCGAATTGCGGGCCTGGGCGGAGCAGAATTTGGTCGTCGACGAGCAGGGTGGCGCGACGGCGGCGCAGTTGGCGGCCGCCCAAAAAGCGACCCGCCCGGCCAAGCCCGAGCACCTGGCGTGGGCCGAGTTAAAGCACCTGTGGGCGCACGATGGCCGCGGTTTTGTCATCGACGAGACGGCGCAACTGGCGGCGCGGCTCGCCCGCAAATCCATGCGGTTCGACGTTCATGCGCTGGGCCGCCAGGCCGCGGTCGGCATCGACAAAGCCGCGTTCACCCGCGCCGATCTGGTGGAAGCAATCGGGTCCCGGCTCCCGCCGTCGATCGAAGGCGCCGGGTCGCAGAGCGACGGCAACGCGATCCCCCCGCGGTATCTCATTGAGGGCATCGCCGAGCGGATCGGCATCCGGATCAGCGCCCCACGACTGGCCCATGAACGCGAAGGCCATGAACGATTCACCACCGCCGCGGTGATCGCCGAAGAGGCCGCCATCGTCGATCTCATGGGGGCCCGCGATGAGCGCGCAGCGCTCGCCCCGGCAGCCCTCGACACCGCCGGGTTATCGGCGGATCAAGCCCGAGCGATCACTGCGATTGCGACCTCGCCGTGGCTGATTCAACCGCTATCCGCGCCCGCCGGCGCCGGGAAAACGACCTCGCTCAAAGCGCTGCGCGCGGCCGCGCACCGCGGCGGAAAACCCCGCGTGGTCGTGTTGGCGCCGACCGGAAAAGCCGTCGATGTGGCGGTGCGCGAAGGTGCCGGCGACACCGGCTACACCGTCGATAAAGCCGTCAAGGATCTGCGCAACCGGGAGCTGACATTCGATGCTCGAACCCTGATTGTCGTCGACGAAGCGGGCATGGTCGGCACCCCGCATCTACGCCAATTGCTCACCGCCGCAACGACCGCTGGCGCCAAAATCGTGCTCGTCGGCGACGCCTATCAGCTGGCCCCGGTCAAGGCCCGCGGCGGCATGTTCGCCCAACTCGTGGCCGATCTTCCCTGGGCGCAAAAGCTTTCCGAAGTGTGGCGCATGCGCGACCCTGACGAACGCTGCGCGTCGCTGGCGGTGCGCAACGGCGGCCCGAAACCGTTGCGCCGCGCCGTCGAGTGGTATCGCACCCACGACCGCTTGCACACCGGCGACGCCCTGACCATGGCCCACGACGCGTTAACGGCCTACCAGACCGATCTCGACGCCGGGAAAGACAGCCTGTTGATGACCGACAGGTGGGAAGTCTGCGACGCTCTCAACACCCGCCTGCACCACCAAACCGTGGCTCCGCAAGCGCCCACCGTGGCTGGCGCGCGCGGGCATCGCATCGGCGTCGGTGATGTCATTATTTCGCGGCGCAACGACGCCACCGTGCCCGTCATCGACGCCACCGACCACACCCAAGCGGCCGACCCGGTACGCAACGGGCACCGCTGGCGGGTCTACAAAATCGACCCCGACAACCACCGCGTCTATGCTCGCCGTCTCACTGATGGGGCCCGCGCTATGTTCGCCGGCGAGTACCTGGCCGAGCACGTCCACTACGGCTACGCGGTGACCGTGCACGCCTCCCAAGGAGCCACCGCCGGTGACGCGCTGACCGCGGGCACCGCCCACGCCATCCTCAGTGAGTCCGCCAGCCGCAACCTGGCCTATGTCGCGCTGACCCGCGGCCGCGACGCCAACCACGTCTACACCTACGAGAACAGCACCGCCGACGATTATCTGGCTGAACACGTCCAGGCCGCCCAGGGCCACCGCGGCGTGCACGCCGCGCAACGTGGCACCAGTCGCGAGGCCGCCGCCAGCCTGCGCGCCATCCTGGGCCGCGACGAGCGCGCCCAGACCGTGATGGCGGCCGCGGTCGCCATCGACCGCACCCAGCAGCCCGCAGCGCTGCGTTCCCTGCTCACCAAGCGCGACCGGGTACGCACCCGACTGCGCGCCGAGGACCGCACCCACACCGCTGCTCGTGAGCTGGCCGCCGAGCTGCCCGCGCTACGCCATGAAATCGACTTCGCCGACGTCGCCGGCCGCGCCTTCGCCGGCGCCACCGGCTACCCCATCCCGGCCAACACCCTCGATCACCTCGACGAGGCCCACCGCCAGGTTGTCACCGCGATCGCCCGTGACCTACACGCCGTGCAATCACTGCACCTGTACCCCGGTGCTGACAAGGCCGCCGCCCTCACGGCCATCACCGACGCCGCACACCGCGACCACCGGCACGTGCTCGCCCTACCCGCCACACCCCAAACCCACGCCTACGCCAGCACCCGCCCCTACGCCGACAACGCCGCCCACATCCAGCAGACTCCGACCGAGCAAGCCCTTGCGAAAATCCGCGAGCTGGCCGATGCCGGTCGCCGGCTCCCCCGGGGCAACCTGGTGATCGTCGACGACGCCGACCACCTGGCCGCAAACCACCTGCAGTGGCTCGCCAACAACGCCGCAGCGACCAACACCAAACTCCTGCTGATCACCACCCCGGATCAACGCACACCCGACCACACCCTGACCGCCGCCCTCGACCACCTGCTGCCCTGGGCCCACCACCTCGGCACCCCCGACCCCGCCCACCAACGCACCCGCACCGCCATCGAGCGCACCGAGCACCACCTCGCCGCCGCACCCGACATCACCAGCCCCACCCACCAAGCAGCGCGCGAACTCCTCAACCGACGCGACGCCCTGCTCAACCACTTCAACGAAGAACGCCGGTTTGAACAACGACTCGACACCATTGCCGCCCGCAACCGCGCCCGAGCCCGTAACAAGGACCGCGGCCACGACCACGGACTAGCCCAGATTTTTCGCGAAATGTTGTGAGTTTCGGGGTGTAGATACGCGAAAGTGCCTGTCCTGCAAGGGATAATCGGACTTATCTAAGGTTCAGATCGTTCCAGCTGGAAGGCACTTCGCACGTGAAGAATATCGCGGCCGGGTCGCGGGTGAAAGTGTCGGCCGATGGTCATGGTGTCGTGTCGCATGCCGGGATGGGTATGCTGCGCGAACTGGCCGACCGCACGGGACTGTCAGCGCAGGTCAGCGCCGCGTTGGCCGACACCTACCGCGGCCCGTGGGTGTACGCACCCGGCGATGTCTTCGCTGATCTGGCCGCCGCGGTCGCCGACGGGGCCGATTGCATCGATGGGGTCGGCCAGTTGTGCGGGGACCGTGAGCACGTGTTCGGCGCGAAGGCCTCGACCACCACGATGTGGCGGTTGATCGACAAGCGGATCGATGCCGCGCGCCTGCCCGGGGTGCGGGCAGCACGAGCCGGCGCGCGGGCCGCAGCATGGGCGGCCGGAGCCACCCCCACTGGTGATGGCTGGCTGCACATCGACATCGATGCCACCCTGGTCATCGATCACTCCGACAACAAGACCGGCGCCACACCGACCTGGAAGAAGACTTTCGGTCTTCATCCGCTGCTGGCGTTTTTGGACCGTCCTGAGATCTCCGGCGGGGAAGCCCTGGCCGGGCTGCTGCGCACCGGCAACGCCGGCTCCAACACCGCCTCCGATCACATCATCGTCCTCAAACAAGCGCTGGCGTCGCTGCCGCCGCGATGGCGGCCCCACCCAGGTGCTCGGGCGGATCCGGACGCGTCTGGGGTGTTGGTGCGCTGCGACACTGCCGGAGCCACCCACAAGTTCGCCGACGCCTGCCGCGCCGCCGGGGTCGGGTTCTCCTTCGGCTACCCCGTCGATGTGCGCGTCCAGGACGCGGTGGACACCCTCAACCTCGCCGATGGCTGGTATCCAGCGATCGACACCGACGGCGGGATCCGCGAGGGGGCCTGGGTCGCCGAGGCCACCGACCTGGTCAACCTCAGTAGCTGGCCGGCCGGCACCCGGCTGATCCTGCGCAAAGAACGCCCGCATCCCGGTGCGCAGTTGCGGTTCACCGACGCCGACGGGATGCGGGTCACCGCGTTCATCACCGACACCGAACCCGGTGTCATTGCTGGTCAGGTCGCCGGTCTGGAATTGCGGCACCGCCAGCACGCCCGCGTCGAGGACCGCATCCGCGAACTCAAAGCCACCGGCCTGCGTAACCTGCCGTGCCACTCGTTCTGGGCCAACGCCGCCTGGCTGGAAATCGTGCTGGCCGCCGCCGATCTGGTCACCTGGGCCCGACTGATCGGCTTCCGCGCACATCCCGGCCTGGCTCGCGCCGAGATCGCCACCTTCCGCTACCGGGTCCTGCACGTCGCTGCCCGTATCACTCGCGGCGCCCGCCAACAACGACTACGTATCGATGCCACCTGGCGCTGGGCATCAGCGATCGCGACCGCCTGGCAACACCTACGCACCGCCTTCGGATAGAACCCGGCTCACCTGACCCACCGATCAGAAAGACCAGGCCCTGGGAAAGCCCGCCCACCCGGCGACACGGGACGCCCCACCACGCCATCACACGAAAACACCTACCCGGCAACACAATCCACAGGCAGAACCGACTCCGCACCAACTCAATGCAAAATCGAGGCTAGGGCTCTAAGAGCCGCCAGGTGACCGGGCGCGACATCAACTGCACCGCAACAGTTCTGCACACCAGCACCACACAGAACCGCGACCGTCGCCGCAACCAGATTCCGGGAGTACTCTGCATGCATGGCAGAGAAGTTCACCCTCGATGCAGCCGAAGCCGAATCGGGGTTGTCCACCGCGGATGCCGCCACCGCTGCGCAGCCCAGCAGCAACCTTCCCGGCCTGTGCATCGGCGGCTACATGACCACCTTGCTCGGCGCTGTTGTCGGCGGCCGAGCCATAGGCCAGGCCCAAGCAGAGGCACGCGCGGTAGCCAACACCACCAGCCGCGAATTCAGCATCACCACGATCCAAACAACAGAAGCCGACAACACCAGCCTTCTTACGACTTGAAAAAACTCCGTCAGTTACGTTGTGCCAGTTCGCGGTACACATCGGCCGCACTCGACAACCCAAACCGCGGGGGCCGGCGCAGCGGAGACAACAAAACACGGATCGCCGTATCAATGAGCCGGCACGACACGGCCGCGAACTCCGCGCGGACCGCCGCAGGAGCACCGCCAGCCACCACCAGCCACCAGCAGTGCATCGTCTGGTTCACGTCCGCCACAGCGCCCGTTAAAGCGCACGCACAAACCGCGCACGTCTGCTCAACCGTCGCCTTCCGCGCCAACAACACTTCCAGCTCGCGGCCAACAGCAAGCCGCCGGACCGGATCATCCAGATCCGACAACGTTTCCAGCGACCCCAGCCAAGCGCGCCGCTCCTCCCAACCGCTCAAAGCATCAACATAATTCGCTTCATAAAGCCAATTGCACAGCGCCTCGAACGCTCTCAACGCCAACGCCAACGCCAGCGGCAACGGCGGCCCAGCTTCCTCGAAGCGCACCACGGTGCGCGTCGGACGCGGCTCATTCAACAACTCCGCGAAAACATCATGCTCAGCCAACCGTCAAGCCCCCGTTTTTCGCCAATGGCGCGCGTATACCGGCCACCCACGCCGCGTACACCACATTCAGTGGGTCGTCACCGTAGTACTCCCAGCACAGCAGCGCCTCCAACTGCCGGCACCGAACGAATTCCCTTGTGTAGCTGACAGTCTGATCGGGGTTTTCCAATCCATTCAATCCCGGCCGCTGGCACGCCATCTGCACCAGAGCGTCCTGGTGTTCCTCGCCCAGCAGCGCCCACTCCGCGGCGCTGGGCCGGCGGCCGGCCACCAACGCCTGCCCCACCGACTGAGCAACCGCCGACAGCTCCTCACCGGGAATGCCAAACACCAACTGGCGGACCAACTCTCGGCAGTAATCGCGCACCACCGACTCACCGGCCGCCACCAAATCCGCGTACAAGGCTGCGTCCACCGTTTGCAGGCGGTGAGCTCGCGGCTGCGATAACTTCGCCGCCGCGTTGTCCGGTTCCAGGCTCGGTTTGACACCGTAAGCAACCTGCGGCGTCGGGTGCTCGGCCAAATACTCTGACGGCAGCGCCCACGAGGTGGCCACCGCGCTCACCGTGTCGCCGAACTCCCGCGCTGCCCGCACCGCCTTATCGGCCGGATTCACCCAGCCAAACCAGCGCGCATCGAAATCTGCATCATGTCCGCCCGCGATCGGCATCACTTTGCGCACAAACACACCCGGCGGGATATAGGTCGCGCCGTCGTTGGTGGCCACCCAATACGTCGGCATCCCCGAAGCGTTATGCCCAACGGCCACAGCCCAATCCACACCAGGATCAGTGACTTTCGCCGCCCCAGCCAGTTCGGCGACCCACATCTTGGCCTGCTCCAAATCCGACCAGGCGTCCTCCTTGCGGACCGTCACCACATCACGCCGCCCCGCCACCGGCATCAACCCCGCCCCCGCCCCTGGTGACCCACCTCCGGCCTCGGCAGGAACCGATGGCGCGGCAGGCGGCGAACCCACCGGCGAAGCCGCCGGTGCGCCCTGGGGAGGCAACACCGACCCGTACGACGTCATGCCACCTGCTGGCATGCCCGCCGCCGGCGCCGGGCTTGGGGCTGAAGTAGCTGCCGGCGGCGTAGTCGGTATCGGAGCGGCTGCCGGCGCCGCCGATGTCGGAGCAGTCTCGATCGGCGCCGTCAACGGCGTCATCGGCGCCGCCGGCGTCACCGGCGGAACCCCACCCGCCGCCGCAGCACCCGCCGCTAAACCACGCCCGAAGTCCATCCCCAACGACGGCATCGGAGAACCCTGCAACCCAGACGCACTCAACCCCGTAGGCGAAGGCATACCACCGGGAAGACCGCCAAACCCACCCATCAGCCCCTGCAACGGGCCCATAGGAAGCCCGCCCCCCGAGCCACCCCCAGGCATACTCGGCAAACTCGGCAAGCCACCACCCATCAGCGACGTCAACGGGTTGTGCTTTGGGGTCGGGATATTATCCGACCAATGCGGCGACAAAGGCCCGCCGGACCCGGGTGCCTTGCCTATGCCGTCCGACCACTGATCGGCCTTGACATTGCCTCGGCCTGGAATTGGGTTAGTGGGGTCGCCCGGGCCTGCTTGTGGGGGAGAATCTGGATCGGACCACGAATCCGACCGCGTTCCATTCCCCGCCTCTCGTACCTGACGACCACCACCTGGCCCGCCTAACTTGAAGTGGTTGGTGAATTGGGTCGTGTATTGGGTGGCATAGCCCTGCAACTCAGATGAATACCCTTGGATCGTCGCTCGATGTGCACCAAGGACTACCGCCAACTGCGCAAGCGACTGCCCCGAGCCACTTCGCAGAAACGCGAAGGCCTCTTGATGTGCCTGCTTGTTCACCTCGAACATATGCCTCTTGATGCCCGCCACATCCTCGGCGCCGCGCCTGATCAAACCGGAAGCAACCCTGTTGATCTCCGCCTCGAAATCCTTGATCGACGCCGCCTCAAACTGGGCCGCTCGACCAGCGTCCCCGCTCTCACCCACCCACGACCCACCGTCAAACACCCTGTTCGCCGCCTGGCGGATCGTCGCCGCCCCGCCATCGTGCAGCTTGAAATCCCCAGCACACTGATCCGCGGCGGCATTCAAGGCCGTCTCAGAGTCTTCCGGCCAGACAAACGGCTGAAACAAAAACCTGACGAACGCGCCCTGCGGCCGCGGATAATCACTACTGACATGTGGCAGTGACGCTGGCTGGATACTGCGCACTGGCCCCTGGTTCACCACCCTCAGCAGCCGCTCCGCCTGCTCCTTATTGCGCTCCACCCACCAGTCCGCAACCTCAACCCCATCCCCGTTCGGGCCTATCACCGACGCCATCTCGATTTACCTCGGCAATCCGCACACATCGAGCAGCGCCTCGATCGCATCGTTGCGGACGTCCGTTAGGCGATTACCTTCGCTCGTTGGCGTGTTGCCCATCGCGGCCGTCGTTTGATCCAGCGTTGCCGTGACGTACTTCCGAGCTGCGGCCGCGACATCGGGAGGTACTGCCGGAACAAGGGTGTTCTGTACTGCTGACGCACTATTTAGGGCACGAACCACTACTGGCATGTTTAGGTTCCCCTGCACTCGGAGTCCCCCTTGGCCCTCTTGTCCGCGCACCGACACGTCGAATACTTGGCACAGGTGATTTTTTGCCGCCGTCGCATCAGCCGCGCTGAACTGTGGCGCCGCGCTTGAGGACACCGGCACCGGTGGAGGTGGGGCGGCGACGTTGTCCTTACGCAGTGCCATGGTGAGCGCCGACGCCACGGCAGCCGACACTCCCACTACGCCGATCCACTTGAGCGCCGCACCGGCCCGATAACGCCCCCGCGGCAGTCCCACAGGTGGAGACCACCCGGGTGCGGTTGGCGCTGCCGTCCTTTGCGGTGCACCGGGCGGCGCCGGAGGCAATACCGCGGACGGCGGCGCCTCTTTCGACCAGGGGGATTCCCCCACGCCGGGCGGGGGTGTAGGCCTTTCTTGGCTCATCGGTTAATCGTATGCACGCCTGGTGACATTGCGCTGCAGTCGGACTCGGCGAAACTTCGCCGCGCCGGCGCAACCGATCACTCAGAATCCAATACCGCCGGAAGAAGGAAGAAAGCGCTTCGTTCAGCAGACCGAGTGTCTCGTATCTAAAGAAACGGGACGCCTGGCGCTGGACACTCCCCTGCTCTGTCACCCCAGGTCGCGGTGTCTCATTTCTCGTCTCACACCGCGTGTCTCGAATCCTCGATGTCGTCGGGCGGTGAGACAGTACCCACGTGGCAGTGATCTTGGGTTATGCCCGCGTCAGCAGCACGGGCCAAGACCTCGATGCACAGCTGGCGGCCTTGGCAGCCGCCGGCGTCGATGACGAGCGGGTCTATACCGACAAACTGTCAGGTGCAGCTAACACCGATCGTCCTGGGCTGGCTGCACTATTGGACTACGCCCGCGCTGACGATATCGTCCTCGTCACCGCGATCGACCGCCTCGGTCGCTCGGTTGCCGAAGTCACTCGCACCATTGCTGACCTTAATGAGCAGCGAATCGTGTTGCGCGCCATGCGGGAGGGAATCGACACGGCCACCTCGGCAGGCCGCGCTGTCGCCGCCATCATGGCTACGTTGGCCGAACTCGAACTCGAACTCGGTCGCGAACGCCGCGCAGCTGCTCGTGAATCACGGCGGGTTCGCCGACTGCCAGCCACTAAGCCGCCCAAGCTCAGCGCCGAACGGCAGGAGCAATTGCGACGACTTGCGGCCACCGGCGAACCAGTGGGTGAGCTGGCGGCCGCGTTCGGGGTGGGTCGAGCCACGGCGTACCGCTACCTTGCTTCTCCCTCTACCGATGCAGCACAACGCTGAATAACACGAGGACGTTGACACATCCGATGAGCAGCGACAGTGCTCCTGCCGCGTCGTATGAAGTCAGCGCCTGCGATCGGTGATCAGCGCACCTGTGGAGGAAGCCTTTTCGGGGTTGCTCGCAGCGGCGGGTCCCGTCGTTTATCCAGGCACGACACTTGCTGAGCAGTTCCCAACCGATACCGAATGGCGCCACGACCAGGACGACAGTAATCATCCAGAGCGTCCACGATCCGTGCGGCCGTGGCACTAGGAGCACCAAGATCAGCAAGTCAGCCGTGCTGATTCCGCCCCATACCTGTGGCGCTCGATCGACCGGCCGCCCGTGTACGACACCTCCAGTAGAGCTTCCTAGGGCATTAGTTGACCGGCTCGCACCGCCGTAATTGACTAGATCGCCCAGCCCGCTGCTACCCCAGCCGTGCCCCGCGTAAGGGCAGATAGTCCCAGGCCGATGTCGCCCCACCCGGCACCGTGCATCGTATTGACACAAGGCTGACCCCTCTCAGTTCCACCCACCTCGGCTCAAGTATGTGTCGAACGACTGACATCCTCCTCCTGGCCAACACCGAGGAATTGTCAAGACCTGTGGATTGGGGTGTTTCAGGCGACCTCCGTTTCGGCTGATTCGGCCGGTTCGGGTGGTGTGATGTCGACGGGCCGTTCGAGTAGCTTGCCCTTGTGGAAGACCGCGCCGGCGCGGACCAGGGCGACCAGGTGTGGTGCGTTGACGGCCCTCCAGCGGGCTTGTGCGGCGTCGATCAGCTTGTAGGCCATGGCAATTCCGGCCGCGCGTGATCCGGGGCCCTTGGTGACCTTGGTTCTCAACCTGACGGTGGCGAACGTCGACTCGATCGGGTTGGTCGTTCTCAAGTGGATCCAGTGTTCGGCCGGGTAGCGGTAGAACTCGAGCAGCACGTCGGCGTCATCGACGATCTTGGCGACCGCCTTGGGGTACTTGGCCCCGTAGTCCACTTCGAAGGCCTTGATCGCGACCTGTGCGTGGTCGATGTCCTCGGCGTTGTAGATCTCCCGCATCGCCGCCAACGCACCGGGGTGGGCTGACTTGGGCAGGCAGGAAAGGACATTGGCCTGCTTGTGGAACCAGCATCGCTGCTCGCGGGTAGCCGGGAACACCTCGCGCATCGCCTTCCAGAAGCCCAGTGCACCATCACCGACAGCCAGCACCGGGGCGGTCATCCCGCGGCGTCGACACGACCGCAGCAGATCGGCCCACGACTCGGTCGACTCCCGATACCCATCGGCCAGCCCAACGAGCTCCTTTCGGCCATCGGAACGCACGCCGATCATCACCAGCAAGCAGAGCTTCTCCTGCTCCAACCTGACCTTGAGATGAATGCCGTCGACCCACAGGTACACGTAGTCGGTGCCCGACAGATCGCGCTCGCCGAAGGCCTTGGCCTCGTCCTGCCACTGCGCGGTGAGCCGAGTGATCGTGGTGGCCGACAGCCCGGCACCCGAGCCGAGGAACTGTTCCAACGCGGGACCGAAGTCACTGGTCGACAAGCCGTGCAGATACAGCAGCGGCAGCACCTCGGTCATCTGCGGGGACTTACGCGCCCACGCCGGCAGGATCGCCGAGGAAAACCGCCGCCGCTCAGCGGTATCGGCGTCGATACGCTTGTCGTTGACCCGCGGCGCGATCACCGTCACCGCACCCGCCGCGGTCAACACCTCACGCTCGCGGTGATAGCCGTTGCGGACCACCAGCCGATGCCCGTTCTCATCGACCTCCCCAGCATGGGCGTCGATGTAGGCGGCGACCTCGGCGGCCAACGCCGCCGCCAGCATCTGGCGGGCACCGTCGCGGACGATCTCATCGAGCAACGACCGCGACCCGCACGCGTCCTCGTTGGAGGAATCCTGGTCGTGAACTACCGTGAGCATGGGCGTACCTTCCCAACCAGCGCGCCAACGCCGGTCTTGATCAGAGCTACTGGACTTTCAGATCATCCTCGGGAAGGTGCGCCCATTTCTCACGCGCCCCGCCGAGGCTCATCCACAGGTTCTGATCATTGCTCGCCAACACCACAGATGGCTTGTAAGGCATCGTCGGATTGACGGGGAAAATCGGGCGCCAATCGCCTCCACCAGATCAGCCCGAGTGAGCCGTCTTCTGGTACGCCGTGACCGTGCGGTGGCGCGCTCTCGGATTGATCGGCCAAGGCGGCTGCTTGTTGCGCTAGCTGCACCGTTGCGCTTGCCTAATCTCCCATGACGACGACCCCACTGCGCACTCTGACCTCGACGTGACCGCGCGCCATATCTACATTGACGAAACCAAAGAGCGCGGCTACGTCCTAGTTGCCAGCGCCCACATTGCCGACAACCACCTCAGCGAACTACGCAAAACCATGCGCGAATTCGTCCTGCGCGGCCAGACCCGTGTCCACATGGCTAAGGAAAGCGACCAGAGGCGGCGCACAATATGCGCCGCCATCTGTGCCGCCAGTGTCAACGCCACCATCTACGACGCCGGCCGGCGCTACCGAGACCCACTGGACGCTCGCAGCGCCTGTCTGCAAGGCGTCATCAGCGACACCACCGCCGGCGAGGAAACCCTTATCGTCCTTGAACAAGACGATTCGATCATCCAATGGGACCGCCAGCGGCTCATCGAACTCACGCGGGCAGAAAGCCGACGCGACAACCTGCGATACGAACACCGCCGCGCCAAAACCGAGCTGCTGCTCACAGTGCCCGACGCGATCGCTTGGTGCTGGGCGCGTGGAGGCCACTGGAGACGGCGCATCGAGCCCGTCATCGCCACCGTTAAGCAGGTCTAACACGTCCCCGGATGCGCGAAACCCGGCCCGCCCACCGTCCGGAAGGCTGCCGGGTTCACTTCCTGAAGCTCAGCGCAACAGGCACCCACCACTATATCCCAGAAATGGGGGACCAATGAAGGAACACCCACAAGGGGGTTTTAAAGCCCAGGTACCGAACAGATGGCCTTGTAGCCGCGCAACGTGCGCAGCGTAGACATGCAAGCATGTTTACTTACATGTAAGGCTGCATGTAGCCATGCTTGCTTGTAAGGAGGTATGCTGTCCGCTATGAATGTTCCCGCAGATGAGCGGTGTGAAATCGTGGCGGTGGCACTGCAAAAAGGCGGCGTCGGCAAGACGACCACCACCATCAACCTCGGCGCGAACCTCGCGGCAATGGGGTTCCGCGTCCTCGTTATCGACATGGATCAACAAGCCCACAGCACCAAAGGGCTCGGCATCGAGCTCGGCGCCGACGACGCCTCGATGTACGAGGTGCTGCACCCGGACCGGGCGATGCGCGTTCCGCTGGCCAAGGTCATCCGGCCAAGCCAGTTCGGAATTGACGTCGCGCCCGGTCACCTCGCGCTCAAGGAACTCGAGCGCACCGGCCTCGGATCAGGTGGCCAGCTGCGCCTCGCGCGCCAGCTCGACGACATCGAGGGCTACGACTTCGTGCTCATGGACTGCCCGCCCGCACTCGGCGAGTTAACGACCGCAGCGCTGGCGGCCGCCGATTACGTCTTGGCGGTCCTCAAGGCCGGCCCCGATGAAGTCGACGGCCTGGTCGAACTGGGCAACTCGATCCTCGACGTCCAGGAGACGCTCAACCCCGACGTGCAAATCCGATACGTGCTGCTGGCCGATTTCGACGGTAATCCCAAGGCCAGCAAGGATGTTCGCAAGCAGCTGCGCGCCGATTGGGGGGAATGGGACGCCGGCGGGGCATACCTCGGCGAAATTCCGCACACCGTGCGAGTCGTGGAAGCCAAGGGCAAGCGCGTGCCCGTGCACGTGCACGCCCCGACCAGCACGGCCGCGGTGGCATACCGAGAGGTCGCCGAACGCATCGCGGCCAGGCGGCAAGCAGCATGAACGCAGCCAAGCCCAGCGGTCTAGAGATCGGCTCGACCAGACCCCTATCTCGCGCGGAACGCCGGGCCGAGGCCGCACGAGTCAAAGCCGACGAAGCTCTCCCCGAACCGGCAGCAGCCAGCCCATCGCCGCAGAACGATGACGTTCCGCCGGCGCCGGCGGTAACCCCCGACCGCGGAAACGAAGCCCCCGAGCCGTCAGTGCGGTTGAAAGCCCGACAGCGCAAGGCGAAAAACCCGTTCGCTACGCAACTGCACCCAGGAACGCTGGCGCGGCTCGAATGGATCAAGGCCCGCGGATACGTCATCACCGACACCGTCGACGACGCCATCAACACCTACCTCGACGGCGCCGGCATCCCCAGGCCAGACGAAAACGACCGCATGCCCAGCTGAGAGGCGATGTCCTTCCTCGCCGCCAATTGTGGCGAACGTGGGGGTGCCGGCTGTCAAGGCCACGCCGCTACGCGGTCGACCACGGTCGAGCCTTGACAGCCAGCACCCCCACGCACAACAGCGGCCACTACGAGGAAGGGCATACCGCGAAGGCACACAAACGTCAGGAGTGCCCTATCAGGCCATCCGCGTTGGCATAATGGACGCCACACCCACCCGTCCCTGCTGGGGGCGGGTTTTTGTCACCCGTGATCACGCGATGAGTCTGTTACTTTGGGATTACCAGACTTCCAGATGGCAAAGGTGACTCGCCGCTATGCCTCACGATGACGACCCGCGGCCGGGTCAATGGGTGCGCTACGACCAACTCGAACGCAAAGAGACCCGCCTACGCCCCGATCAGTACAGCCGCCTGAGCAGCATTAGCCGCGCCCTCAACCGGGCACGGGCCGGCAAAGGCGAGCGGATCACCGAAAACACGCTCATACGAGTGGCGATCGATCTACTGCTCCAGCGCGAAACAGAGCTGGCCGGCGACACCGAAGGCGAACTCCGTAAGTCCCTAGGGCTATAACTTCGGAACTCTGTTACTCTGTAAGTTGTGACTACGGCTGATCAGTTCCTCACCGTTGCGGTCGCCAACGTCCGCGCATTCAACCACGCAACAACGGCGACCCAGCTAGCCGACCGCCCCATCACCGCCGACCAGGCCTACGGCATTCTTGACGCCGCAGAAATACTCACCCAGCTCATGCCGCAGGCCTTCATCAGGCTCGGCCTGGCCGTAGGACAGTCGCTCACCGCCCACGGTGACCCCGCCGACATCGACCTGGTGATCACCGCAGCCGCGGCACACATGGTCCAAGCCGCCCAACTCATCTCAGACGCAAGCGAGAAAATCGCCCCACTGCTTGACCACAGCGACGCCGACGATGAGCGCCGGCGCCGGCGGCCGAGGGTCGAGGGCATTCGCCGCTGGGTCTCAAAGGCCGCCTAAACCCCAGTCACGAAAACATCACGGACACATGTGGCAATGTCAACTTGAAGTGGCCCCAGTGTGACGGCTAGTTTTGGCCCCCCCTTCGCGGTGCGTTGGGATTTTCTGGCGTTGAGGTGGCTAGCCCCAGAAGATGCCTGAGGGGTTGTGATCGATTTCGGTGAGCACATCGTGGATGTGCGGTGTGGGGTCGATCGTGTCGTAGCGGTGAAATTTGAGGTGTCGGTCTCGCCAGTACAGGGTCCAGGTGTTGGTGGTGGCGGTGTAGCGCAGTCGTGCGATCGGGAAACTGGTCCAGTCTGGACCGTAGTCTTCGCGCCACGGCGCTCGTCGTTCGACGATGGTGAGGTGCCGGGCAGCGACGTCGCATTCGACGCGGACTTGGTGACGCGCGTGTTCGGGCACTCTGGCCGCGCACCACTGTTGCACGCGTGCGATATCGAGTTCGGGTAGGGCCATTGGGTCACCACCGGGGCGTGTCGGTGGCGGCGGTCAGGGTGTCGTAGGCGGTGTCGAGTTGGCGTTGACGGCGGCGGTGGGGTTCATGATTGGACTCGGCAGCCAGAGCATCGATCAGGTCGTCGAGTTCGGCGGCGGTCATCGTGAGATGAAGCTCGCCGCCGTGGGCGCAGATCGCGAAAACCGCTCTCTGACAGTTGTTGTCGAGGAAGGGCAGGGTGCGCAGGGTCGCTGCGGTGTCAGCGTCGATGGGAATGTCGCGGCGCGGTTGGGCTGCGGTCAGTTGCTGGCGACGCAGATCGTAGATTGATGCTGCCCAGTTGCTGATGGTGCCGTCGTCGCCGCAGTGGCTGCATTGCCAGCCGATGGGTTGCTCAGCATCGCCGCGGACCACCGTGATGCGGCCCGGGCAGCGGCGGTTGGCGGGTCGGCGCCGACACGGCAGCGCGGTTTCCCACCGGGTGTGAGCGTCGCCGGCCGACGCTGCGGAAACGATGCCGCCCAGGTGCTCGGCGAGCGCACGGGCCGGCCCGGGGTCTCGGGGCCCACGTCGAGGAAGTGCTGCAGATCGGCGACCAACATGACCTGGTCACTGTATCGGCTGCAGGCCGGCCAGAGGCGCGTGAGTTACTGCGCGGTGCTGGTGCGGCGGGTGCGGGCATGGGCGAGTCGGTGGAGGTGGTGCCGGTTTCGATGATCTGCCCGGCGAAGGTCAACCGGTCGACGATGGCCGCACACAGTCGCGGGTCGGTGAAGGTCTTGGTCCACGCGGAAAACGGCTCGTTGGACGCGATCGCCACCGAGGCGCGTTCCTCGCGCTCGGTGAGCACCTGAACAGCAACTCCGCACCGCGGCGGTCCAATTGCAGGTAGCCCAGCTCATCGATGAGCAGCAGATCCACCCGACCGTAGCGGGTGATCAACTTACTCAGGTGGGCCTCGTCGGCGGCCTCGACGAGTTCATTGACCAGCTTGCTGGCCAGGGTGTAGCGGACGCGGTAACCGGCTTCGGCGGCGGTGGTTCCCAACCCGATCAGCAGGTGAGTCTTGCCGGTCCCGGAGTCGCCGATCAAGCACAAGGGTTCACCGGCTTTTGACCCAGGCGCAGGTCGCCAGGGTGCCGATGACTGCGGGGTTGATCGCGGGGTTGGCCTCAAAGCTGAACTCGTCAAGCCGCTTTGGCCGAGGGAACCCGGCGTCATGAATACGGCGCTGCGCCCGGCGGCGATCCCGGTCCTCGCATTCGGCGATCATCAGCTCCGATAAGAACCCCAGATAGGACTGCTGTTCACGTTCGGCCGCGGCGGCGATCTCGGCGAAGCGGTCACGGATGGTGGGCAGCCGCAACATCCGGGCGCCCTGTTCGATTGCCGCGACCGCGGCCTGATCGGTGACGGTGTGACGCGCGGTGGTGTTCATGAGCTCTGCTGCCCCAGCAGCGTGTCATAGGGGGCCACCGACGGCAACGGCCGCTCGTCGGCGATCAGGCGGTGCTCAGCGAGCCGGAGCACCTGGGCGCCCTCACCGCCGCCGGGTGGCGAACCGAGGCCGGCGCGCTGTTCGGCGGCCCGGCGGGCTTCCAGCGCCACCACATCGGCATTGACCGAGCCCACCGACAGCGCAGCGCTGATACCGGCCAGCACATCAGCGCGGTCGAGGTGACGGTGCAGCAGCAGGACTTCAACCAGCACACGGGTTCCGCCAGCATCCCCATGAACCCGCCGGGCTGCGGCCCACCACGCGTCATGTTCAGCGGTGAACAGTTTGGCCGCCCGCGCTTGAGCCAGTGCGGTGGCCCCCGGCAACGCACCGGGTTTGCGGGCCAGGATCTCCAGATAGTGGTCCAAGTCCAGCACCTTGGTGCCTTTGCCGACTGCCCGGGGATGACGTGCCACCACCGTGGTGCGGTCATAGACAGTGACATGCGACGCCGACAGTTTCACCCGCACACGATGCCCGATGAACCGGGCCGGCACCGAATACTGATTGCAGCGCACCATGATCTGGGCGTACCGATCCACCCGCGGAGTCAGCGTCAACGCCGTCTCAAACCCCTGATCGGCAACAGGCTGCAGGAACTGCCGCTCGGTTTCCCAGTCCTGGCCAACACTGTTGGCGCGGTTAGCGATCCGACGACGATCGTCGGCGTCGTCAGCAGCGGCCAAGAAGGCGTTGAGCTCGTCGATGGAGTCGACCACCGGCATCGGCACGCAGTGATTGCGGCGAAACCGGCCCCCTTCGCCTTCCACGCCGCCCTTTTCGTGGCTGCCGTCGTGACCGGGCTGGCAATACCACGCTTCAAAGCCGTAGTGCGAGCGGAACGCGATCCAGCGTTCATTCTCCTGACGGGACCGTCCGAACAACACCTGCTTGACCGCACTATTGAGATTGTCGTAACGGATCTTGTCGACCGGCACCCCGCCGAGGCGGTCGAACCCGTAAACGTGGCCCTCCAGAAACGCTTCCTGGCCCTGGGTGGCGAACGCCCGATGCGCTGCTCGCCCCGAGAACGACAACCGCATCGTAAACAGTGCGGTCTTGGTCTTCACCCCGGCCAGCATCACCCACAGATCGTGGAAGTCGACCTCGGCTTCAGCGCCGGGTCGGTAGGTCTGCGGCACAAATCCCGCCTCCAAGGCCCGGCCCGCCTCCGCAGCGATCTGTGGGCGACGTTTGCGGATGTGGTCGCGCACCGTCGAATACGACAACCCGGCAGCGTCATGCTCATCGACCAGCCGCGCCAACACCCGTCGCGCGGTATGGCGTTGCTTTTTCGGGGCATCCAGATCCGAACGCAGCATCTCATCGATGGCCGCCTTGAACGGCTCCAACCGCGGCGCCGCTCGCGGCCCGGTCTTGCGCGGCGGCGGCACCGCCGAATCCAACGCTTGGCGCACTGTGCGTCGATGCACCCGGTACTTATCTGCCAGCGCCCGGATCGACAAACCCTCAACCCGACGATCCCGGCGGATCGCTGCGAACTGCTCCACCCGTGTCCTCACCTTTCCAGCCACCAACCCTTCACCAGCGATCCGGGCCATCCGGAACCGCCTGTGATCACTGTCAGGTGGGGCCAATTCACGCCGTCATAACCGACGCGGCGTGTCGTCAAGGTGGGGCCAACTCAGACCGTCACAACAGCACACCCGCGACCACACAGGTGGGGCCACTTTCGACCGCCCACCCGGGGCCAAATCAGGCTGTCACAGCCAATCGGCTTGTACACGGGGAAGCGATGCAGGACGGCGTGGATTGCGTCGAGCTTGTCCAGAGAAGAATCCGGTTATTTCCGCCTGCATCCTGCGAGTCCGAGGCGGTCGGCGGCATCTCGCTGCCAGATGTCAAGACCCGGGTGTGTGCCAAGTGATAGGTCGACGGTTCGGCGTGTTCGTTGGTCGCCTGTCTACCGGATGGTCATGAGGCGTTCGGTCGGCCCGGTGCCTGTAGGTGAGGGCGGGGTGGCAGCCGCGGTGTTTCTGTGGGACGGTGCGGCGCTCGATTCGATGCGGCTGCGGCCGGTGCTCATTGCGGCGATCCCCTCTTCGGGTGCGTTTCAGTAGATCTGCATATCAGTACGCGGATCAATGAGGGGTCCTGCACTTGGGCCCAAGGTGAGGCGCGGCACCCCTCGCGCGTCGTCGGCGATGAGTTGCCGGCGGGCGTCTGCTGAGGCCCTGTGTTGGGGACGGTCTAGGTGCACGCGGCGAGGTGTGACTGCTGATCGGACTACGCAGGGAGCGATTTTTGGCCAACAGCGATACTGAATTCTAGGAAGAAAGGTTTCTGCAGATATCGGGCACCAACCGAGTAAGTCTAGTTTGCTGGCACCTTGAAACTCTGATAATCGTAATCAAGTCAGACTCTGGCCTGAATGATTCACGTTGTGCTCGATATCAGTAAGTACGCAGACGCGAATTGGCGCATGTCAGTACACCAGTACATGGTTGTTGAACTGCTGCAATATACGATTGTAGGTGTGGAAGTCAGTGTCTACTGAAACACTGAATTTATGAATATGAATCACTTTGCAAACAAGGTAGCCCAATTGGCTTGACGCTCACTTTCTGTAGTAGCTAAGCTGCATTGCATAGCCAAAGTTCATACAGCTGGTGGCATTGCTATCACCAGTTGTGGGAATCCAGTTGTGGGAATGGAGGTGAGCCCCATTACCACCTAAGTGACTGTGCAACGCACGACAAGTGCGCCGATCATAACGCGATCATCTAATGATCCATGAATTCGGAGGGGAACATGACTTGCAAGACACGACGCCGCGGTATCACGATCAAGCTCGGCATGGCCGCAGGTGCAGCTTTGGCCGCCGGGCTCATCCCGATAGCCAGCGCGGGCGCTGCCTGGGCGGATGAGCCAGACCCAGGGATCACAGTTGGGGGCGGCGGGTCTGGTGGAGTGTCCACCCCGATCGGTGGGGGCAGGGCGTCGACCGGCGGGTCCGGTGCTTTCAACGACAATGGCGGCGGCTTCGGTACTGGCACGTCGGGCGGTTTGACCGGTCCGGGCGGCGCTGGGAGCGGCGCTTCCACCGGCGCGGGCGGTGGTTTCACCCTGCCGGGATTGCCGGGATTTTGAGGTAGGCACCGCAGCGGGAATCGACATTTGACTGGCGTGGCCGCTAGCCGCGCAGCAACGGATGTCGACATGCGGGGCAAGCGGATGACGCACCCCGAAGCCTCGGGAGAGGACGTTTGCTTGGTGATTGGGACCGGTCGCCCGAGTCGCGCACATCGTGGCCGGGCGACCGCTCGTCGGCGGGTATGACGGTCGGCTGCCGAACACGCCTGGCGCCTGAAGCGGCCACCCATGATGCCGAGCATGAAGTGTTGGTGCGCGCGCCCAGTCGCAAAGTTCGTGATTGAGGCGTGACGGGCGGTCCACCACGCAACGCACGATGTCTTGCGGTCACCATCTTCCACCATCTTCGAGCCAGCGCCCGTTCACATCCGGCCACCAGGTCGGCAACGGGTCGCGGCGGGCAAGGCGGGCGGTTCATCGCGCTGCGCGGCGCACCAGACAGCGCGGTCGCCTGGCGTTTCTGCCGCGCGCTCGCAACGCCGTGCTGCGCCGCTTCATCGAGGCTGCAGTGCGCTTCATCGCGTCGATGAGGTCCTTGGCCTCGCCGATCGATTCCAAAATGGCCACCCGAGCTTGGCCGGCCTCCTTAGTCAGTGGTGTGCCCAGGAGCTGCCAGTCCGAGCGCAGCCAGTCGCGCGCCGCGCTGAGCGCTGATCTCACTTCGTCGATGCAGGCGCGGGCGTTCTCGAATAGTTCGGGACGAGTTGGCAGGTCAGCCATGGGTTGTCCTTTGCGGCGGGTTGTAGCGGGAAGCCGTGGGAGTGACGGCCGGCGAGGTTTTCACCAGCCGGCGTAGGCAAGGGGCAGGTCGGCGATGACTTGTCGGCGTGATTCGTCGAGGCTGGCAGCAATGTCGCTGAGGCCATTTGCGCCAAGTGATCGCAAGAGTTCGCCGCCGGGCTCAGAGTTGTAAAAGCTCACCATCGCCGCAAGGAACATCGCTTCGCCCGAGGACAGCCATCCGATAGCTGATCGGATCTCGTCGACCCTCGGCGAGAGATCCCACTTGCTGGTCGCGCTGTCCGGGGAAGTCTGGCCGTCGGCGAACCATCGGGGACCGGCGATCTCTACACCGCGCTGCCACGCTTGAAAAACGGTCTCATCATAGAAACGTGCTGACATGTGTTCTCCTCCTGAGCCGTTCATGAGTTTCTTCCAGGTGTGACAATCGTTATCCCGAGGGCACGGGCGGCGTCGCTGAGTCGACTGTCATAGGCGACCATGGCGGTCAATGGTGCTGTGGATGCGGCGATTTGAGCGGTGGCCAGGTGTATCGCATCGAGCGAGCGCAGCGCCGGATCGGGGTAGGCGGCCGCGGTGGCGCGGATGACCTGGTCGATTTCGAACCGATCCAGTCTGGCCAGCACAGAGGGGACAGCAGATAAGCCATTTGGGGCGACTGCGCGGATGGCTCTGGGGAGCTCCACTTCAGCCAAGGCAGATGTTATCCAACGTGTTTCGGTGCGTTCATCGAGCCAGTCAGCTAGAGCATCAGATTCGACTTCGATCCGGATCAGCTTGACCAGAGCCGAGGTATCCAGGTAGATCACCGGCTAATACCTTTCCTCGGCGCGCAGACGTTGCAATAGCGCGCCGGCGTCGAGATTGTCGTGCATCGGAACGGTCGGCCGCGGGGCTGGGCCGGCCAGCGTCGCCGGTTGCACTCTGCCGGCAGTGATCAACGCATCCAGTGGGCCGGCGGTAGCGGGGATTATTCGGGCGATGACTTCCCCGCGCTCAGTAAGCGTGATCTCTTCGCCACGCTTGACGCGGGCCAAGACCTTTGCCGTCTCTTGGTTGAGCATTCGGAGAGGTACTTCACTCATACCAATAATGTACTACATAGTTGTACTACATGCTATGGTGGCGCAACTGGTTCGGAGCGCCGGCGGCCCATGTCCACACGCCCGCCCCCGAGAATCAACCTATCGACGAAGCCGTTCAGGAACTCCGCGCCGGCCTCGTCGTCAGGCTCGCGGCCATCGGTGCTCACAAAGGGACCTATCCGTCTCTAGCTGCCTTGTCAGCTCAATTCTCACAGGTGGGGCAGAGATATGCGACGGTCAGCGCGTGGTTATACGGCCGAGCCATTCGCTTGATGCCGGCGGTCTGCGGGCGGTGCCGCTCAGTCAGTGCCGTCGTCCCGACCATTGGTGGCGCCAGCCACTCGGCCAACCTAGCCTTGACCTGCTCCGCCTGCTCCCGACTGTGGCACATGTCGTTTGCCATCTTTCCGAGTGTTACGCGGCAGGGGAGAAGGTCAAGTCCAGGGACGTGGTGTACGACGTCGTCGTGTGATTCTTCGACTTGGTGGTTTAGGCGGTCAGTGCCGCCGGGGTGTCCTCCTGTTCTGTTGATGGCGTGTGGTCGGCGCGGGATTTGCTGAGGACGTCGAGGCCGAGGTAGCGGCGGGATTCGGCCCATTCGTCGTGTTGTTCGGCCAGCACCGCGCCGACGAGGCGGATTAGGGCGTTGCGGTCGGGGAAGATTCCGACGACGTCGGTGCGCCGGCGGATTTCCTTGTTGAGTCGTTCTTTTATCCGGCCCTCGGGGGCGGGTCAACCCGTCGGGGTGGGATGTCATCGATCGAGGCGCTGGAGGTGGTCGGTAAGGGCGTGGGCGACGCGGTCGTGGCGGGCGGCTTCGTCGGTCCAGCCGCGGCACTCGGCGTCGGTTCTGAGGGCCTGGACGTCGGCGAGTTGGTCGGTGAGCGTGTCGCGGAATTCGGGGGCGGTGACGTAGTTGTCGCAGGTTTCGCAGATGTTGGCATAAGGGCACGCGCCCGCGGATTCGTGGCGAGCGCAGTATCCGTGTGCAACGCGGGTTTTCAGCATTTCACTGTGCAGCCAGCCGACCTTGTCGGGCAGGATCGGTTTGCCGACCGGGGTGAGGGTGAACTGGCGGCGCATCTTGCCCATCGCTTCGTCGTAGGCCGCGCGCAGGGTGGGCGAGGCCAGGGTGGCGTAGCGGATCGTCATTTGTGGAGTGACGTGCCCGAGTAAGGACATCAAGGCCTGCAGACTCATCCCGGCGTTGGCGAGTTCGGTGGCCCAGGTGTGGCGCAACTGATGTGGAGTGACCATCAGGACGCCGCCGTCGGGACGGTGCAACCCGGCGGATTCAGCGGCGGTGAGCAGCCCGTTGCGCAGCCGGGTGTAGCCCAGGCGGCGTCCGTGCCGGGTGAACAGAAAGTCGGTGAGCACGCCGGTGCGTGGGTGCGGCAGCGGCCGGTGCGTGCCGCGGAGGGCGACCCACTCGTCGAGCGCGGCGAGGGTCGCGGCGGAGAGCGGGACCATGCGTTCGGTGGCGAGCTTGCCCAGTGGCACCTTCAGCCAGGTTCCGGCCGGTCCGTAGTCGATGATGCTGCCCAGTTCGAGGTCGAGCAGTTCCCCCGCCCGCAGGCCGGCACCACGCAGCACGGTCAGGCCGATGCGGGCGAACGGATCCTGCAGGTGGGCAACGGCGTTCATCACTGCCGCGTCCACATCGGGTGCTAGCGCGCGTGGCAACGGCTGGTCGAGTTTGGGGACGTCGGCGGCGAATACCAACCGCCGTGGTGGGGCCTGCGCCCAGCCCAGGCGGTGATGTCGTCGAGCAGGTTGCGCAGACTGAGCACTGCCGACTGGGCCACCGCGGCCGAGACGGTGCGCCCGGCGCCCGCGGCGGCGCGCTGACCACGCCAGCCCCGGGTGCGATTCCATTTCAGGTAGCCCTCGATGCAGCTCCGGTCGAGTTCACGCAGGCTGATGACGTCGGGATGGTGAGCGGTGAGGTATTCGGCGAAGGGCAGCAGGTCGTTGATCAGCGACTCGACCGATTTGGGCCGCAGCACCGCCGCGCGCACGCCGATGTAGCGCAGCAACGTCTGACGGATCGGGTCGGGCATCTCCACCTCGGTGAAGCGCTGCTCGAGGCTACGGGCCCACCGCCGGCGTTTCGGCGCGGTGTCGATGACCGCGGTCTCGAACAACAGCTGCCGCAGGCTGGCCAGCCGCCCCTGTATGCCCGCCGCGACGATGGCGGCACCACGGTACGTGACAGCGCGGCGTCGAAGTCGTCGAGCGCGTCGCCGGTCAGGTCGGCGACCATTCCGCCGTGGTGTGCCAGCACTACCGCCAGACATTCGCCGAGGACCGTCTCGACCCAGGAACTCCTCCAGCCCAACCGAATTCCCGCATTCCGCAACGCGGCGAATCCGCTCGGATCCCGGTCCTCCACTGCGCGGCCCAGCCCGGTCAACTGTTTGACCGCGGCCAGCTCGACGTCCAGCCGTAACCGGCCGGTGCCGATCGTGTGACAGATCAGCGGCCACGCCCCGGTGTCCCGTATCTCGGCGATCCGCTCGGCTGCCGGCAGCGTCATCCAGGCGTGCAGGTCGCGGTGGCGTGCGGTGAAGTCGCGAGCGATCCGAATCCGGTCGCGTACCGCCCGCCCGCTCAAACCCAGGGTGGCGACGTGGTCGAGATAATCCGCCACCACCTCGTCGGCGCCTACGGGTTGGCCGACCAACACCGTGGTCACTGCCGGGCTCCGGCCAACGTCGCACGAGCAGCACCGTATTCGGCGGCGAGCTGCTCGATCGACAAATGCACGTAGCGGGCCGTGGTCTCCGGCGAGACATGCCCCATCAACGCCCGCAACGCCAGCAGATCGATTCCGGCCGCCGACAATTCGGTGCCGTAGGTATGCCGTAAACGGTGCGGGCGGACTCTTGTGGCGCCAGAGGTCTCCCGGTGCCGACGGAACAGGCTGCGCAGCCCGGCCTCGCTGACCGGTGCACCGGTCGTCGGGCCGCGCAGCACTACGAAGCACTGCGGCGTCGCCAACCCCGGCGGCCGCTCCCATCGCAGGTAGGCGGCGAGCTCGGTGAAGAACGCCGCATCGACCGGGACATGACGTTCCTTGCCGCCCTTGCCGATCACCCGAAGCCGGCGCCGGCCCATATCGACGTCGGCGAGCAGCAGGCCACGCGCCTCGGCCGAACGCAGCCCTCCGAGTAGCATCACCAGCACCATCGCCCGGTCCCGGTGCGTTGCCAGTGTCGCCAGGAACGCGTCGACATCGTTGGTGGACAACGATTCCGGAAGACGCTGCGGCTGACGCACCAACCTACCGCCACTGCGTGCACGCCCGGGACCCAGATGACCGAGCAACCCCCGCTGCGACTGGCGCAGCCCCTGTCCCCCCGCGGCGACGGCACCGGATTGTCGGTGCAGACACCGGTCATCACCAGATACTCGAATAACGCGCGCACTGCCGCGACCCGGCGGTTCACCGTCGAAGCTGCCGGCAGGGGTCGACGAGCGGTGACCGCCGGTGGGCTGGTCCGTTCGGCGGACGCCTTGCCAGTCGATCCAGTCGAACACCAACGGCGCATCGACCGCGGCGAGCCCGACCGCTTGCTGGACGAGGAACCGGCTCAAATTGGCGACGTCGAATGCGTAGGCCCGCACCGTGGCCGCGCTGAACCCCCGTCCCGCCAAATGGTTGAGAAACGCGTTCACCGCGTCCTGCCCGTCCCAGTCGCCCTCCAGGACATATCCGCTGTCGCTCTTGAGTACCCGCATCGCCGCTCCGCCTTCCCCCACCGAGATGCAGACAGCATCCATCCGTGCTCAGCGCTTGTGCGTGAACCTCACGCTGCAGCCCGAACCGTGTCCCCGGAGAGCCGGTTAACGGATAGTGGGTTGTTGGACCAGATCTGCCGCCAAATTTGTTTGGGGAAGGCGGTGAAGGCGAGCAGGTCGGCGCGGGCGTCTTCGAGGTGGTCGGCGACCTTGGGGAGCTTGTCGGCCAGTGCGTCGATGATGCGGTCATATTGGGCTGCAACGGAACCGGCGTCAGGTTGATCGAAGACCGAATGCAGTAGTGTGCGTACCCACGGCCACGATGATTTCGGAGTGATGGCCATCAGGTTGGTGGCGTAGTGGGTGCGACACCGTTGCCACGATGCCCCAGGCAGGGTGGCGCCGATCGCGGCCACCAGACCGGCGTGGGCGTCGGAAGTGACCAGACGGACCCCTGATAGGCCGCGGGCGGTCAGCGACCGCAGGAAGGTCAGCCAGCCGGCCCCGTCCTCGGCGGTGGTGACGTCGATGCCCAGGATTTCGCGGTAGCCCTCGGCGTTGACCCCGGTGGCGATCAGCGCGTGCACGTTGACCACCCGGCCTGCTTCGCGAACCTTGAGCACCAGGGCGTCAGCAGCCATGAACGTGTACGGGCCTGCATCCAGTGGCCGGGTCCGGAACGCCTCGACCGCGGCGTCGAGCTCTTTGGCCATCACGCTGACCTGGGACTTCGACAAGCTGGTGATGCCCAGAGTCTCGACGAGTTTGTCCATCCGCCGCGTCGAAACGCCCAGCAGGTAGCAGGTAGCCACCACCGTGGTCAGGGCCCGCTCGGCGCGTTTGCGCCGTTCCAGCAGCCAGTCCGGGAAGTACGAACCTTGCCTTAGCTTGGGAATCGCCAGATCCAATGTGCCTGCGCGGGTGTCAAACTCGCGGTGCCGATACCCGTTGCGGGAATTGGTGCGCTCGCTGCTGCGCTGGCCGTAGCCGGCACCGCACACCGCGTCGGCTTCGGCGCCCATCAGGGCGTGAATGAAGGCGGCCAACAACTCGCGCAGCACATCAGGGTGCGTGGTGGTGAGTCGTTCGGCCAGCACGGCAGACAGGTCGATATCGTGGGCAATGGTCATCGCGTTGATTCCTTTGCTCGAGTGACTTTGGTCGGTCCCTCGAAGAATCAC

Protein sequences of DBSCAN-SWA_2

>NZ_CP040250|1693950:1731208|1719529_1719868_-|WP_062887574.1|DBSCAN-SWA
MALPELDIARVQQWCAARVPEHARHQVRVECDVAARHLTIVERRAPWREDYGPDWTSFPIARLRYTATTNTWTLYWRDRHLKFHRYDTIDPTPHIHDVLTEIDHNPSGIFWG
>NZ_CP040250|1693950:1731208|1718013_1718412_+|WP_062889965.1|DBSCAN-SWA
MNAAKPSGLEIGSTRPLSRAERRAEAARVKADEALPEPAAASPSPQNDDVPPAPAVTPDRGNEAPEPSVRLKARQRKAKNPFATQLHPGTLARLEWIKARGYVITDTVDDAINTYLDGAGIPRPDENDRMPS
>NZ_CP040250|1693950:1731208|1709741_1710287_-|WP_062888002.1|DBSCAN-SWA
MAEHDVFAELLNEPRPTRTVVRFEEAGPPLPLALALALRAFEALCNWLYEANYVDALSGWEERRAWLGSLETLSDLDDPVRRLAVGRELEVLLARKATVEQTCAVCACALTGAVADVNQTMHCWWLVVAGGAPAAVRAEFAAVSCRLIDTAIRVLLSPLRRPPRFGLSSAADVYRELAQRN
>NZ_CP040250|1693950:1731208|1721282_1722869_-|WP_062887208.1|transposase|DBSCAN-SWA
MRTRVEQFAAIRRDRRVEGLSIRALADKYRVHRRTVRQALDSAVPPPRKTGPRAAPRLEPFKAAIDEMLRSDLDAPKKQRHTARRVLARLVDEHDAAGLSYSTVRDHIRKRRPQIAAEAGRALEAGFVPQTYRPGAEAEVDFHDLWVMLAGVKTKTALFTMRLSFSGRAAHRAFATQGQEAFLEGHVYGFDRLGGVPVDKIRYDNLNSAVKQVLFGRSRQENERWIAFRSHYGFEAWYCQPGHDGSHEKGGVEGEGGRFRRNHCVPMPVVDSIDELNAFLAAADDADDRRRIANRANSVGQDWETERQFLQPVADQGFETALTLTPRVDRYAQIMVRCNQYSVPARFIGHRVRVKLSASHVTVYDRTTVVARHPRAVGKGTKVLDLDHYLEILARKPGALPGATALAQARAAKLFTAEHDAWWAAARRVHGDAGGTRVLVEVLLLHRHLDRADVLAGISAALSVGSVNADVVALEARRAAEQRAGLGSPPGGGEGAQVLRLAEHRLIADERPLPSVAPYDTLLGQQSS
>NZ_CP040250|1693950:1731208|1726013_1726286_-|WP_033711258.1|DBSCAN-SWA
MSEVPLRMLNQETAKVLARVKRGEEITLTERGEVIARIIPATAGPLDALITAGRVQPATLAGPAPRPTVPMHDNLDAGALLQRLRAEERY
>NZ_CP040250|1693950:1731208|1701045_1702095_-|WP_138017755.1|integrase|DBSCAN-SWA
MRVLKSDSGYVLEGDWDGQDAVNAFLNHLAGRGFSAATVRAYAFDVANLSRFLVQQAVGLAAVDAPLVFDWIDWQGVRRTDQPTGGHRSSTPPAASTVNRRVAAVRALFEYLVMTGVCTDNPVPSPRRGTGAAPVAAGLLGHLGPGRARSGGRLVRQPQRLPESLSTNDVDAFLATLATHRDRAMVLVMLLGGLRSAEARGLLLADVDMGRRRLRVIGKGGKERHVPVDAAFFTELAAYLRWERPPGLATPQCFVVLRGPTTGAPVSEAGLRSLFRRHRETSGATRVRPHRLRHTYGTELSAAGIDLLALRALMGHVSPETTARYVHLSIEQLAAEYGAARATLAGARQ
>NZ_CP040250|1693950:1731208|1717210_1718017_+|WP_062890007.1|DBSCAN-SWA
MNVPADERCEIVAVALQKGGVGKTTTTINLGANLAAMGFRVLVIDMDQQAHSTKGLGIELGADDASMYEVLHPDRAMRVPLAKVIRPSQFGIDVAPGHLALKELERTGLGSGGQLRLARQLDDIEGYDFVLMDCPPALGELTTAALAAADYVLAVLKAGPDEVDGLVELGNSILDVQETLNPDVQIRYVLLADFDGNPKASKDVRKQLRADWGEWDAGGAYLGEIPHTVRVVEAKGKRVPVHVHAPTSTAAVAYREVAERIAARRQAA
>NZ_CP040250|1693950:1731208|1716403_1716940_+|WP_062890008.1|DBSCAN-SWA
MTARHIYIDETKERGYVLVASAHIADNHLSELRKTMREFVLRGQTRVHMAKESDQRRRTICAAICAASVNATIYDAGRRYRDPLDARSACLQGVISDTTAGEETLIVLEQDDSIIQWDRQRLIELTRAESRRDNLRYEHRRAKTELLLTVPDAIAWCWARGGHWRRRIEPVIATVKQV
>NZ_CP040250|1693950:1731208|1725602_1726010_-|WP_007168487.1|DBSCAN-SWA
MIYLDTSALVKLIRIEVESDALADWLDERTETRWITSALAEVELPRAIRAVAPNGLSAVPSVLARLDRFEIDQVIRATAAAYPDPALRSLDAIHLATAQIAASTAPLTAMVAYDSRLSDAARALGITIVTPGRNS
>NZ_CP040250|1693950:1731208|1693950_1695303_+|WP_046184758.1|transposase|DBSCAN-SWA
MPSPGRPSVAWRQDRVRFWAGIAAGAMTEDAATEAGVSSPVGFRWFRHAGGVNPRLPETVSGCYLSSNEREDIALWRAHGAGVREIARRLRRAPSTISRELRRNASTRTYRLDYKASVAQWHAERRARRPKTAKLVGNDRLRQYVQDKLSGVVRGAYGQIMAGPAATPWKGRNKPHRGDRAWVTAWSPEQIAHRIKLDFPDDESMRISHEAIYQALYVQSRGALKRDLITCLRRGRALRVPRARSRQKAWAHVTPETLISARPPEVADRAVPGHWEGDLLIGLQRSAIGTLVERSSRFTMLIHLPREAGYGLIPRTKNGPALAGYGALTMANALAQTITSLPEELRRSLTWDRGKELSAHAQFSIASGVKVYFADPKSPWQRGTNENTNGLLRQCFPKGTDLSRWNADDIAAIAHTLNTRPRKTLGWRTPAEAFNEHLHSLQQAGVATTD
>NZ_CP040250|1693950:1731208|1704029_1707671_+|WP_138017784.1|DBSCAN-SWA
MLSISKPMKRHSVRYYNDTARAAISASADRQRAGGGLAEYYSEGETRAPVWVCVGESGDAEKAAALVGLSAADRAGGPADLDVVARWLDEGIAPNGAQGRAFSARSTHGFDLTFGAPKSVTLLRAVSGDDVLAKAVVEAHNHAVREALEYLYDHAGYTRVHNPDTGKKDLVRLPGLVMAAYQHETSRDGDPHLHTHVLLPNTQARGDGTLVSVDSKSLHHEAKAAGIIYQATLRHHLLQSVGLEWGPIDPRTGMAEIAGVDRATIKSWSQRSTELRAWAEQNLVVDEQGGATAAQLAAAQKATRPAKPEHLAWAELKHLWAHDGRGFVIDETAQLAARLARKSMRFDVHALGRQAAVGIDKAAFTRADLVEAIGSRLPPSIEGAGSQSDGNAIPPRYLIEGIAERIGIRISAPRLAHEREGHERFTTAAVIAEEAAIVDLMGARDERAALAPAALDTAGLSADQARAITAIATSPWLIQPLSAPAGAGKTTSLKALRAAAHRGGKPRVVVLAPTGKAVDVAVREGAGDTGYTVDKAVKDLRNRELTFDARTLIVVDEAGMVGTPHLRQLLTAATTAGAKIVLVGDAYQLAPVKARGGMFAQLVADLPWAQKLSEVWRMRDPDERCASLAVRNGGPKPLRRAVEWYRTHDRLHTGDALTMAHDALTAYQTDLDAGKDSLLMTDRWEVCDALNTRLHHQTVAPQAPTVAGARGHRIGVGDVIISRRNDATVPVIDATDHTQAADPVRNGHRWRVYKIDPDNHRVYARRLTDGARAMFAGEYLAEHVHYGYAVTVHASQGATAGDALTAGTAHAILSESASRNLAYVALTRGRDANHVYTYENSTADDYLAEHVQAAQGHRGVHAAQRGTSREAAASLRAILGRDERAQTVMAAAVAIDRTQQPAALRSLLTKRDRVRTRLRAEDRTHTAARELAAELPALRHEIDFADVAGRAFAGATGYPIPANTLDHLDEAHRQVVTAIARDLHAVQSLHLYPGADKAAALTAITDAAHRDHRHVLALPATPQTHAYASTRPYADNAAHIQQTPTEQALAKIRELADAGRRLPRGNLVIVDDADHLAANHLQWLANNAAATNTKLLLITTPDQRTPDHTLTAALDHLLPWAHHLGTPDPAHQRTRTAIERTEHHLAAAPDITSPTHQAARELLNRRDALLNHFNEERRFEQRLDTIAARNRARARNKDRGHDHGLAQIFREML
>NZ_CP040250|1693950:1731208|1718728_1718986_+|WP_081248522.1|DBSCAN-SWA
MPHDDDPRPGQWVRYDQLERKETRLRPDQYSRLSSISRALNRARAGKGERITENTLIRVAIDLLLQRETELAGDTEGELRKSLGL
>NZ_CP040250|1693950:1731208|1713548_1714133_+|WP_081248532.1|DBSCAN-SWA
MAVILGYARVSSTGQDLDAQLAALAAAGVDDERVYTDKLSGAANTDRPGLAALLDYARADDIVLVTAIDRLGRSVAEVTRTIADLNEQRIVLRAMREGIDTATSAGRAVAAIMATLAELELELGRERRAAARESRRVRRLPATKPPKLSAERQEQLRRLAATGEPVGELAAAFGVGRATAYRYLASPSTDAAQR
>NZ_CP040250|1693950:1731208|1714736_1716041_-|WP_011724019.1|transposase|DBSCAN-SWA
MLTVVHDQDSSNEDACGSRSLLDEIVRDGARQMLAAALAAEVAAYIDAHAGEVDENGHRLVVRNGYHREREVLTAAGAVTVIAPRVNDKRIDADTAERRRFSSAILPAWARKSPQMTEVLPLLYLHGLSTSDFGPALEQFLGSGAGLSATTITRLTAQWQDEAKAFGERDLSGTDYVYLWVDGIHLKVRLEQEKLCLLVMIGVRSDGRKELVGLADGYRESTESWADLLRSCRRRGMTAPVLAVGDGALGFWKAMREVFPATREQRCWFHKQANVLSCLPKSAHPGALAAMREIYNAEDIDHAQVAIKAFEVDYGAKYPKAVAKIVDDADVLLEFYRYPAEHWIHLRTTNPIESTFATVRLRTKVTKGPGSRAAGIAMAYKLIDAAQARWRAVNAPHLVALVRAGAVFHKGKLLERPVDITPPEPAESAETEVA
>NZ_CP040250|1693950:1731208|1725240_1725582_-|WP_007168486.1|DBSCAN-SWA
MSARFYDETVFQAWQRGVEIAGPRWFADGQTSPDSATSKWDLSPRVDEIRSAIGWLSSGEAMFLAAMVSFYNSEPGGELLRSLGANGLSDIAASLDESRRQVIADLPLAYAGW
>NZ_CP040250|1693950:1731208|1719013_1719409_+|WP_062889964.1|DBSCAN-SWA
MTTADQFLTVAVANVRAFNHATTATQLADRPITADQAYGILDAAEILTQLMPQAFIRLGLAVGQSLTAHGDPADIDLVITAAAAHMVQAAQLISDASEKIAPLLDHSDADDERRRRRPRVEGIRRWVSKAA
>NZ_CP040250|1693950:1731208|1709461_1709731_+|WP_062888004.1|DBSCAN-SWA
MAEKFTLDAAEAESGLSTADAATAAQPSSNLPGLCIGGYMTTLLGAVVGGRAIGQAQAEARAVANTTSREFSITTIQTTEADNTSLLTT
>NZ_CP040250|1693950:1731208|1707766_1709173_+|WP_011724501.1|transposase|DBSCAN-SWA
MKNIAAGSRVKVSADGHGVVSHAGMGMLRELADRTGLSAQVSAALADTYRGPWVYAPGDVFADLAAAVADGADCIDGVGQLCGDREHVFGAKASTTTMWRLIDKRIDAARLPGVRAARAGARAAAWAAGATPTGDGWLHIDIDATLVIDHSDNKTGATPTWKKTFGLHPLLAFLDRPEISGGEALAGLLRTGNAGSNTASDHIIVLKQALASLPPRWRPHPGARADPDASGVLVRCDTAGATHKFADACRAAGVGFSFGYPVDVRVQDAVDTLNLADGWYPAIDTDGGIREGAWVAEATDLVNLSSWPAGTRLILRKERPHPGAQLRFTDADGMRVTAFITDTEPGVIAGQVAGLELRHRQHARVEDRIRELKATGLRNLPCHSFWANAAWLEIVLAAADLVTWARLIGFRAHPGLARAEIATFRYRVLHVAARITRGARQQRLRIDATWRWASAIATAWQHLRTAFG
>NZ_CP040250|1693950:1731208|1730095_1731208_-|WP_094494180.1|transposase|DBSCAN-SWA
MILRGTDQSHSSKGINAMTIAHDIDLSAVLAERLTTTHPDVLRELLAAFIHALMGAEADAVCGAGYGQRSSERTNSRNGYRHREFDTRAGTLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLLGVSTRRMDKLVETLGITSLSKSQVSVMAKELDAAVEAFRTRPLDAGPYTFMAADALVLKVREAGRVVNVHALIATGVNAEGYREILGIDVTTAEDGAGWLTFLRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGASWQRCRTHYATNLMAITPKSSWPWVRTLLHSVFDQPDAGSVAAQYDRIIDALADKLPKVADHLEDARADLLAFTAFPKQIWRQIWSNNPLSVNRLSGDTVRAAA
>NZ_CP040250|1693950:1731208|1712040_1712484_+|WP_132160601.1|DBSCAN-SWA
MCTKDYRQLRKRLPRATSQKREGLLMCLLVHLEHMPLDARHILGAAPDQTGSNPVDLRLEILDRRRLKLGRSTSVPALTHPRPTVKHPVRRLADRRRPAIVQLEIPSTLIRGGIQGRLRVFRPDKRLKQKPDERALRPRIITTDMWQ
>NZ_CP040250|1693950:1731208|1710279_1711191_-|WP_062906138.1|DBSCAN-SWA
MPVAGRRDVVTVRKEDAWSDLEQAKMWVAELAGAAKVTDPGVDWAVAVGHNASGMPTYWVATNDGATYIPPGVFVRKVMPIAGGHDADFDARWFGWVNPADKAVRAAREFGDTVSAVATSWALPSEYLAEHPTPQVAYGVKPSLEPDNAAAKLSQPRAHRLQTVDAALYADLVAAGESVVRDYCRELVRQLVFGIPGEELSAVAQSVGQALVAGRRPSAAEWALLGEEHQDALVQMACQRPGLNGLENPDQTVSYTREFVRCRQLEALLCWEYYGDDPLNVVYAAWVAGIRAPLAKNGGLTVG
>NZ_CP040250|1693950:1731208|1695930_1696257_+|WP_007168431.1|DBSCAN-SWA
MKWNLRLTAANRGIWKASELQRMLAERGLVISAGKMSGLWSGNPNAIKLHDLDVFCAVLDCAIDELLIPEPETVAAPTPKGSEEAAAAAGEARPVTPRARTGRSLPPR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046184758.1|1693950_1695303_+|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.3e-32	34.6
WP_007168431.1|1695930_1696257_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
1696239:1696256	attL	NA	NA	NA	NA
WP_138017755.1|1701045_1702095_-|integrase	tyrosine-type recombinase/integrase	A0A166YH27	Gordonia_phage	5.0e-08	27.1
WP_138017784.1|1704029_1707671_+	relaxase domain-containing protein	V5UQN3	Mycobacterium_phage	8.3e-103	33.4
WP_011724501.1|1707766_1709173_+|transposase	IS1380-like element ISMav7 family transposase	A0A222ZN33	Mycobacterium_phage	2.6e-84	44.2
1708399:1708416	attR	NA	NA	NA	NA
WP_062888004.1|1709461_1709731_+	hypothetical protein	NA	NA	NA	NA
WP_062888002.1|1709741_1710287_-	hypothetical protein	NA	NA	NA	NA
WP_062906138.1|1710279_1711191_-	hypothetical protein	NA	NA	NA	NA
WP_132160601.1|1712040_1712484_+	hypothetical protein	NA	NA	NA	NA
WP_081248532.1|1713548_1714133_+	recombinase family protein	G8I4U3	Mycobacterium_phage	2.5e-41	54.6
WP_011724019.1|1714736_1716041_-|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_062890008.1|1716403_1716940_+	hypothetical protein	A0A068F3M6	Mycobacterium_phage	1.7e-44	49.4
WP_062890007.1|1717210_1718017_+	AAA family ATPase	Q8JL10	Natrialba_phage	7.6e-17	35.8
WP_062889965.1|1718013_1718412_+	hypothetical protein	NA	NA	NA	NA
WP_081248522.1|1718728_1718986_+	hypothetical protein	NA	NA	NA	NA
WP_062889964.1|1719013_1719409_+	hypothetical protein	NA	NA	NA	NA
WP_062887574.1|1719529_1719868_-	DUF3024 domain-containing protein	NA	NA	NA	NA
WP_062887208.1|1721282_1722869_-|transposase	IS21 family transposase	NA	NA	NA	NA
WP_007168486.1|1725240_1725582_-	hypothetical protein	NA	NA	NA	NA
WP_007168487.1|1725602_1726010_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_033711258.1|1726013_1726286_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_094494180.1|1730095_1731208_-|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.0e-67	44.2