CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040229	Staphylococcus aureus strain GD487 chromosome, complete genome	11 crisprs	cas3,DEDDh,DinG,csa3,TnsE_C,WYL	4	1	8	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040229_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_1

260352-260432

Orphan

Consensus_repeat	Method
TTACAATAATGTGCAAGTTGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_1

>merge|NZ_CP040229|1|260352-260432|CRISPRCasFinder
TTACAATAATGTGCAAGTTGGCGGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGC

>NZ_CP040229|1|1|260352-260432|CRISPRCasFinder
TTACAATAATGTGCAAGTTGGCGG	GGGCCCCAACACAGAAGCTGGCGAAAAGTCAGC
TTACAATAATGTGCAAGTTGGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_000922329.1\|257032_257737_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP040229.1\|WP_000337367.1\|267700_268693_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_CP040229.1\|WP_001066542.1\|266090_267467_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP040229.1\|WP_001792906.1\|253037_253481_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_CP040229.1\|WP_000182750.1\|261716_262631_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_CP040229.1\|WP_000757874.1\|264190_265189_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP040229.1\|WP_000806128.1\|270693_271614_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NZ_CP040229.1\|WP_000975356.1\|247641_249363_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|376098
NZ_CP040229.1\|WP_000607067.1\|253473_254175_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_CP040229.1\|WP_000750483.1\|262658_263063_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_CP040229.1\|WP_001159764.1\|265569_265962_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000062645.1\|254515_256807_+\|nitric-oxide-reductase	unknown	unknown	gnl\|CDD\|225795
NZ_CP040229.1\|WP_000645457.1\|252184_252925_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_CP040229.1\|WP_000570073.1\|270020_270680_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP040229.1\|WP_000608834.1\|249506_250181_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_CP040229.1\|WP_000164008.1\|258692_260129_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_CP040229.1\|WP_000066924.1\|257885_258677_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225101
NZ_CP040229.1\|WP_000736799.1\|269018_269969_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|226451
NZ_CP040229.1\|WP_138766919.1\|263077_263959_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NZ_CP040229.1\|WP_000925394.1\|250442_252182_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_000922329.1\|257032_257737_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.76404e-62
NZ_CP040229.1\|WP_000337367.1\|267700_268693_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	2.86355e-151
NZ_CP040229.1\|WP_001066542.1\|266090_267467_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.94981e-30
NZ_CP040229.1\|WP_001792906.1\|253037_253481_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64
NZ_CP040229.1\|WP_000182750.1\|261716_262631_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	1.07143e-143
NZ_CP040229.1\|WP_000757874.1\|264190_265189_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	7.74259e-99
NZ_CP040229.1\|WP_000806128.1\|270693_271614_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	3.89511e-07
NZ_CP040229.1\|WP_000975356.1\|247641_249363_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	8.99017e-35
NZ_CP040229.1\|WP_000607067.1\|253473_254175_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_CP040229.1\|WP_000750483.1\|262658_263063_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	4.08879e-70
NZ_CP040229.1\|WP_000062645.1\|254515_256807_+\|nitric-oxide-reductase	gnl\|CDD\|225795	COG3256, NorB, Nitric oxide reductase large subunit [Inorganic ion transport and metabolism].	4.56088e-179
NZ_CP040229.1\|WP_000645457.1\|252184_252925_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	7.57134e-152
NZ_CP040229.1\|WP_000570073.1\|270020_270680_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.1821e-66
NZ_CP040229.1\|WP_000608834.1\|249506_250181_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	8.35569e-154
NZ_CP040229.1\|WP_000164008.1\|258692_260129_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_CP040229.1\|WP_000066924.1\|257885_258677_+\|hypothetical-protein	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	4.11077e-54
NZ_CP040229.1\|WP_000736799.1\|269018_269969_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.52422e-32
NZ_CP040229.1\|WP_138766919.1\|263077_263959_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	1.33364e-115
NZ_CP040229.1\|WP_000925394.1\|250442_252182_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0

>NZ_CP040229.1|WP_000164008.1|258692_260129_+|6-phospho-beta-glucosidase
MTKLPQSFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVNTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NZ_CP040229.1|WP_000066924.1|257885_258677_+|hypothetical-protein
MSNKYKDQAQDILTAVGGVENIVDVSYDTVRMTIHMHHAIPSTANEVTQIDGVASVDENETQLVIVFNEEVKYVYQQLQLLMDDAKHQEDTNHDAVDTQETEQKAQAKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHKEFKVIAPFSGKVSMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQEQGYNSDVIVVISNSSDFNKVELTMNEIITTEDVIFKIFKN
>NZ_CP040229.1|WP_000922329.1|257032_257737_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEIATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDQLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_CP040229.1|WP_000062645.1|254515_256807_+|nitric-oxide-reductase
MSMQSSYKRLVKVLLTILVIVFSILLVGGWYIFKNEAPRPTKIVDQQGHTLVTKGELISGQAIYEKYGLTDYGSYLGNGSYLGPDYTAEALHHYLIGMRKYYAQDIYHKQLHKLNHVEIAVVKDKVMKEIRINRYSEKEDQLVLTPGQVYGLKYLQDYYKKEFVNNPKQVGLNENMIKQFQNDDYMVAGNKIEHLSQFFFWGAWLSSTDRPGKTFSYTNNWPYDVDAGNTLPSAGILWTAISVTLLIAGLAFIIYIQKRYEFDMKPTYESERELPKIEVDSKITDSQRKVGKYLVVVMLLFLVQILLGELLAHYYVENKFFGIEIQRLFPFNIAKTWHVQLVIFWVATTWLAAGIYIVPKVLGNEPKKQGVLVDILFWALIIVVMGSMIGEWSHILGWIDSHWWLFGHFGWEYIELGKFWQILFIVGMVLWVIILCRGFLPAIRNKVQVNHDKRHLLTLLFVGAIAIPLFYLASLFIMPNSHVTFADYWRWWIVHLWVEGIFEAFAVVLIGFLMVNMKLTTIETTIRALYFQLILLLGTGIVGMGHHYYWQGDHSIWLALGSCFSALEVVPLCLLIWEAYTHYRLYKKSDIAFPYKGTFIFLASTGLWNAIGAGALGFLINTPAVNYFEHGTQWTAAHAHGSMAGVYGMFSIAIALYVFKNITKKEFWTPKVEKWIKISCWALNVGLAGMVFVTLIPVGYIQLKDGLEDGYWHSRLTSFYEQPLVKAIMWGRMPWDIIFTVGVIILVVIFIRGYRHLKPKYRV
>NZ_CP040229.1|WP_000607067.1|253473_254175_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_CP040229.1|WP_001792906.1|253037_253481_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_CP040229.1|WP_000645457.1|252184_252925_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASTIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_CP040229.1|WP_000925394.1|250442_252182_+|sensor-histidine-kinase
MLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_CP040229.1|WP_000608834.1|249506_250181_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNEVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_CP040229.1|WP_000975356.1|247641_249363_+|glycosyltransferase-family-2-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKVEDQPQWINALGDFIQAVPVRVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGQYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMVMGMLSQTSENEVQILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_CP040229.1|WP_000182750.1|261716_262631_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTTEEKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEIPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_CP040229.1|WP_000750483.1|262658_263063_-|D-ribose-pyranase
MKKTAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_CP040229.1|WP_138766919.1|263077_263959_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHRIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALIYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_CP040229.1|WP_000757874.1|264190_265189_-|LacI-family-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSECLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMMIVAPYDMMANMSTRVTGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_CP040229.1|WP_001159764.1|265569_265962_+|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKDNYNKYIQGQKQRVIFENGHFV
>NZ_CP040229.1|WP_001066542.1|266090_267467_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGDHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIIIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTSLQPSQYIIAVVIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATITFIVSIVLMILGSLSAYMIIPKTVKS
>NZ_CP040229.1|WP_000337367.1|267700_268693_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSIHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPAPANLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_CP040229.1|WP_000736799.1|269018_269969_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSYYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
>NZ_CP040229.1|WP_000570073.1|270020_270680_-|ABC-transporter-ATP-binding-protein
MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLLRMIAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENIKFFKSLCKNSINDTTINEYLQQLNFNDTSAKVSTLSGGNKRKINILVGLLGQPRILILDEPTVGIDLKSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWAYTYY
>NZ_CP040229.1|WP_000806128.1|270693_271614_-|ABC-transporter-permease
MKPYIQLVVFKQWLQYILLVTTIVTALVLIGMGYRVAHDNFKIPITIQDLDQTTASKSFVNKIKQSDYVTIKKVDEDESYIEDDVTKKEAILSMQIPKGFSQKLKENRLKETIQLYGRDDFIGGIAVEIVSSSLYEQQIPNIIYEHLEDMKQHQSIDAINKSYHKHTPESKIKFVSLTKQAQHSISISLIFAVILFVSAVQVVLHYRLNQQAALQRLSQYHLSRFKLYSTYVMTHTILLLLVLLAVSLYLSQPLSLIFYLKSLLLILIYEIGIVFILFHIQTISHRLFMTFIYALAMGIVYLTIFM

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Crispr_ID: NZ_CP040229_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_2

614201-614308

Orphan

Consensus_repeat	Method
AAAGGAACGCAGTTGGATGCTACCGCACAACTGCATAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_2

>merge|NZ_CP040229|2|614201-614308|CRISPRCasFinder
AAAGGAACGCAGTTGGATGCTACCGCACAACTGCATAAAGCCTCTAATCACTAGAGTTCAAGAGGCTTTAAAGGAACGCAGTTGGATGCTACCGCACAACTGCATAAA

>NZ_CP040229|2|2|614201-614308|CRISPRCasFinder
AAAGGAACGCAGTTGGATGCTACCGCACAACTGCATAAA	GCCTCTAATCACTAGAGTTCAAGAGGCTTT
AAAGGAACGCAGTTGGATGCTACCGCACAACTGCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_010922824.1\|615397_616348_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP040229.1\|WP_000808883.1\|604601_605540_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP040229.1\|WP_138766934.1\|608530_609052_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP040229.1\|WP_000901759.1\|613395_614031_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP040229.1\|WP_072434949.1\|610869_611253_+\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP040229.1\|WP_001018677.1\|620634_621009_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP040229.1\|WP_000365352.1\|616402_617122_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP040229.1\|WP_001222139.1\|618709_619426_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000169038.1\|623078_623303_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP040229.1\|WP_000633790.1\|605985_606522_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP040229.1\|WP_001826156.1\|605563_605755_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_001021133.1\|611249_612911_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP040229.1\|WP_000180233.1\|607207_608503_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP040229.1\|WP_000362963.1\|617105_617906_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP040229.1\|WP_000735556.1\|618041_618548_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_001045424.1\|619594_620383_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP040229.1\|WP_000477504.1\|606691_607168_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP040229.1\|WP_001200750.1\|609550_610561_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP040229.1\|WP_016187114.1\|614419_615247_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP040229.1\|WP_001807864.1\|621956_622886_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_010922824.1\|615397_616348_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	6.43614e-48
NZ_CP040229.1\|WP_000808883.1\|604601_605540_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	1.23356e-168
NZ_CP040229.1\|WP_138766934.1\|608530_609052_+\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	3.27957e-96
NZ_CP040229.1\|WP_000901759.1\|613395_614031_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	5.92839e-91
NZ_CP040229.1\|WP_072434949.1\|610869_611253_+\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.66881e-54
NZ_CP040229.1\|WP_001018677.1\|620634_621009_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP040229.1\|WP_000365352.1\|616402_617122_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	5.71997e-38
NZ_CP040229.1\|WP_000169038.1\|623078_623303_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	3.83351e-14
NZ_CP040229.1\|WP_000633790.1\|605985_606522_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.37974e-25
NZ_CP040229.1\|WP_001021133.1\|611249_612911_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP040229.1\|WP_000180233.1\|607207_608503_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	3.99954e-151
NZ_CP040229.1\|WP_000362963.1\|617105_617906_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.7852e-26
NZ_CP040229.1\|WP_001045424.1\|619594_620383_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.07146e-34
NZ_CP040229.1\|WP_000477504.1\|606691_607168_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP040229.1\|WP_001200750.1\|609550_610561_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP040229.1\|WP_016187114.1\|614419_615247_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.69801e-72
NZ_CP040229.1\|WP_001807864.1\|621956_622886_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	6.93341e-34

>NZ_CP040229.1|WP_000901759.1|613395_614031_+|endonuclease-III-domain-containing-protein
MLGTDELYKLLYRHMGPQNWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIRPSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKAELRKELLTLKGIGSETADVLLVYIFERIEFIPDSYTRKIYNKLGYENTKSYDQLKKVITLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP040229.1|WP_001021133.1|611249_612911_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNILLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIVKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP040229.1|WP_072434949.1|610869_611253_+|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQATTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP040229.1|WP_001200750.1|609550_610561_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADVIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP040229.1|WP_138766934.1|608530_609052_+|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVAKKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKVILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP040229.1|WP_000180233.1|607207_608503_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVSPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGKIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP040229.1|WP_000477504.1|606691_607168_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP040229.1|WP_000633790.1|605985_606522_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQGLDYQWIDVTQHRFKPIRDVRHIEESITDYEDDYQEILDKVLASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTANKPGDIMKDNYALARATEWNQLLQ
>NZ_CP040229.1|WP_001826156.1|605563_605755_-|hypothetical-protein
MGIQFLFVGAHPQLALPVEFLFEILCVGPLTRIEKSLLQAHFRSVNYCQYNFVEHRTLIYVPA
>NZ_CP040229.1|WP_000808883.1|604601_605540_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINFLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVNALEKIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVIENIKAADIVLSKDEIQYIDELFPIED
>NZ_CP040229.1|WP_016187114.1|614419_615247_+|ABC-transporter-substrate-binding-protein
MKDNDKQSSDDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP040229.1|WP_010922824.1|615397_616348_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP040229.1|WP_000365352.1|616402_617122_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKIDNKGENYGSIY
>NZ_CP040229.1|WP_000362963.1|617105_617906_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP040229.1|WP_000735556.1|618041_618548_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLANTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNENGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP040229.1|WP_001222139.1|618709_619426_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFILNFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTLDAMIHNPQSAQTFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP040229.1|WP_001045424.1|619594_620383_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLESHFLNVTKKIFEHSGHAPHIEEPEAFLSYYLNFLKSVS
>NZ_CP040229.1|WP_001018677.1|620634_621009_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP040229.1|WP_001807864.1|621956_622886_-|DMT-family-transporter
MLLFYIIGVIVGMFIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIVLNIFINPDVFSLHFFSNQTFNYTWFVGGLLGVGYLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIITMNQINKCNLLLTNQKHLIFWLLLGFTFGFFPPIQTTINSLLASHTHSPAFASLVSFTIGSITLLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP040229.1|WP_000169038.1|623078_623303_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNIVTEQVARDSMNALVDLNILKSNSGAITKVHSAQIIDKTTTVLFEAKK

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Crispr_ID: NZ_CP040229_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_3

776358-776440

Orphan

Consensus_repeat	Method
CACCCCAACTCGCATTGCTTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_3

>merge|NZ_CP040229|3|776358-776440|CRISPRCasFinder
CACCCCAACTCGCATTGCTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCACCCCAACTCGCATTGCCTGTAGAA

>NZ_CP040229|3|3|776358-776440|CRISPRCasFinder
CACCCCAACTCGCATTGCTTGTAGAA	TTTCTTTTCGAAATTCTCTGTGTTGGGGCCC
CACCCCAACTCGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_000057561.1\|773499_774939_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP040229.1\|WP_001224800.1\|773006_773492_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP040229.1\|WP_000006551.1\|778720_779665_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP040229.1\|WP_000513301.1\|772159_772999_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP040229.1\|WP_000816293.1\|782845_783748_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP040229.1\|WP_000134958.1\|775005_775941_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP040229.1\|WP_000662684.1\|767765_770612_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP040229.1\|WP_000369722.1\|776708_777620_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP040229.1\|WP_000229253.1\|765772_767758_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP040229.1\|WP_000675901.1\|781004_782639_+\|NAD-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|237414
NZ_CP040229.1\|WP_000070836.1\|784450_785080_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP040229.1\|WP_138766941.1\|786920_787931_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP040229.1\|WP_000958224.1\|771221_772154_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP040229.1\|WP_001049165.1\|780234_780822_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP040229.1\|WP_000538141.1\|764620_765271_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP040229.1\|WP_071938136.1\|770641_770872_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_001074744.1\|788069_789260_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP040229.1\|WP_001248939.1\|777616_778612_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP040229.1\|WP_000654030.1\|785854_786868_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP040229.1\|WP_000638419.1\|765267_765504_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_000057561.1\|773499_774939_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.86204e-06
NZ_CP040229.1\|WP_001224800.1\|773006_773492_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.7022e-30
NZ_CP040229.1\|WP_000513301.1\|772159_772999_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.21225e-120
NZ_CP040229.1\|WP_000816293.1\|782845_783748_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.98978e-153
NZ_CP040229.1\|WP_000134958.1\|775005_775941_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	1.80771e-153
NZ_CP040229.1\|WP_000662684.1\|767765_770612_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP040229.1\|WP_000369722.1\|776708_777620_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP040229.1\|WP_000229253.1\|765772_767758_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP040229.1\|WP_000675901.1\|781004_782639_+\|NAD-dependent-malic-enzyme	gnl\|CDD\|237414	PRK13529, PRK13529, oxaloacetate-decarboxylating malate dehydrogenase.	0
NZ_CP040229.1\|WP_000070836.1\|784450_785080_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	7.04966e-05
NZ_CP040229.1\|WP_138766941.1\|786920_787931_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP040229.1\|WP_000958224.1\|771221_772154_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP040229.1\|WP_001049165.1\|780234_780822_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP040229.1\|WP_000538141.1\|764620_765271_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP040229.1\|WP_000006551.1\|778720_779665_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP040229.1\|WP_001074744.1\|788069_789260_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP040229.1\|WP_001248939.1\|777616_778612_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP040229.1\|WP_000654030.1\|785854_786868_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP040229.1\|WP_000638419.1\|765267_765504_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34

>NZ_CP040229.1|WP_000134958.1|775005_775941_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIETKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP040229.1|WP_000057561.1|773499_774939_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMANQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVIENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP040229.1|WP_001224800.1|773006_773492_+|acetyltransferase
MRKFLSKTYHHTNPLWHVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP040229.1|WP_000513301.1|772159_772999_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPGEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP040229.1|WP_000958224.1|771221_772154_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP040229.1|WP_071938136.1|770641_770872_-|hypothetical-protein
MYEFYSCIPIFKYTIAVANDKEPIHNKSLVILYHFCPAPSFDLCLATLDRSYLNIILFTHLFFLLFITKLIKRSEG
>NZ_CP040229.1|WP_000662684.1|767765_770612_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLAFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKINRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDN
>NZ_CP040229.1|WP_000229253.1|765772_767758_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP040229.1|WP_000638419.1|765267_765504_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP040229.1|WP_000538141.1|764620_765271_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP040229.1|WP_000369722.1|776708_777620_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP040229.1|WP_001248939.1|777616_778612_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP040229.1|WP_000006551.1|778720_779665_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP040229.1|WP_001049165.1|780234_780822_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP040229.1|WP_000675901.1|781004_782639_+|NAD-dependent-malic-enzyme
MKGIELLNNPFLNKGIAFTNEERKQLGLEGLLPANVRTLEQQAEQCYEQFKAKQTDFEKRLFLMAIFNRNRTLFYKLTSEHLVEFMPIIYDPVIAQSIEQYNENFSRPQDAVFLSVDRQDQIEQELRNVANGRDIRLIVVTDAEGILGIGDWGVDGVDIAIGKLIVYTAAAGINPSQVLPVSLDVGTNNEQLLNDDLYLGNRHKRVDDETYYAFVDKFVSAVRKEYPNALLHWEDFGRGHAKNILDKYEDTLPTFNDDIQGTGIVTLAGVLGALNISKVNYTNQTFLVYGGGTAGMGITNILKDELIKQGVSEEKANQHFYIMDKQGLLFDDMDDLTEAQQVFAKNRNEFSKTVNWKNLKEVIENIKPTVLIGTSTQTGAFTEDAVKEMLKHTERPMIFPLSNPTKLAEATAQDLLKWTNGKALIGTGIPYNDIEYNGVNYSIGQANNALMYPGLGLGLIASKAKKVNQQILSAASHALGGMVNPDEPGAAVLPPVEKIHQCSRAIAKAVAQSVIDQGLNAETIDDIDKAIEAEIWYPEYKSYI
>NZ_CP040229.1|WP_000816293.1|782845_783748_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQKIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLISK
>NZ_CP040229.1|WP_000070836.1|784450_785080_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQNQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP040229.1|WP_000654030.1|785854_786868_+|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP040229.1|WP_138766941.1|786920_787931_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNVSNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP040229.1|WP_001074744.1|788069_789260_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPDLGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK

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Crispr_ID: NZ_CP040229_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_4

825518-825598

Orphan

Consensus_repeat	Method
TCTTTATCATTTCTGTCCCACTCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_4

>merge|NZ_CP040229|4|825518-825598|CRISPRCasFinder
TCTTTATCATTTCTGTCCCACTCCCAAGAACCAATACATAATAAAGCATAAGTGATTCTTTATCATTTCTCTCCCACTCCC

>NZ_CP040229|4|4|825518-825598|CRISPRCasFinder
TCTTTATCATTTCTGTCCCACTCCC	AAGAACCAATACATAATAAAGCATAAGTGAT
TCTTTATCATTTCTCTCCCACTCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_001018957.1\|821455_821842_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224572
NZ_CP040229.1\|WP_001010508.1\|830860_831325_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NZ_CP040229.1\|WP_001183849.1\|826168_827020_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP040229.1\|WP_000752917.1\|825740_825935_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP040229.1\|WP_000662306.1\|819760_819874_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000267231.1\|834941_836009_+\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|224981
NZ_CP040229.1\|WP_000205572.1\|828207_829515_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP040229.1\|WP_000571213.1\|822380_823406_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP040229.1\|WP_000807673.1\|829629_830871_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP040229.1\|WP_000932205.1\|819875_820754_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP040229.1\|WP_000589549.1\|818801_819158_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP040229.1\|WP_138742457.1\|825091_825313_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000274033.1\|833204_833519_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000168845.1\|827347_828109_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP040229.1\|WP_001074405.1\|831475_832873_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NZ_CP040229.1\|WP_001065802.1\|821834_822131_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP040229.1\|WP_138766944.1\|823398_824094_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224922
NZ_CP040229.1\|WP_000290492.1\|819315_819696_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP040229.1\|WP_138766945.1\|824111_824933_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP040229.1\|WP_138766946.1\|833887_834928_+\|DUF21-domain-containing-protein	unknown	unknown	gnl\|CDD\|226911

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_001018957.1\|821455_821842_+\|hypothetical-protein	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	4.21303e-36
NZ_CP040229.1\|WP_001010508.1\|830860_831325_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	6.42482e-68
NZ_CP040229.1\|WP_138766944.1\|823398_824094_+\|ABC-transporter-permease-subunit	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	1.53079e-99
NZ_CP040229.1\|WP_000752917.1\|825740_825935_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP040229.1\|WP_000267231.1\|834941_836009_+\|nitronate-monooxygenase	gnl\|CDD\|224981	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only].	2.6112e-111
NZ_CP040229.1\|WP_000205572.1\|828207_829515_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
NZ_CP040229.1\|WP_000571213.1\|822380_823406_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.03316e-170
NZ_CP040229.1\|WP_000807673.1\|829629_830871_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP040229.1\|WP_000932205.1\|819875_820754_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16986e-75
NZ_CP040229.1\|WP_000589549.1\|818801_819158_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP040229.1\|WP_138766946.1\|833887_834928_+\|DUF21-domain-containing-protein	gnl\|CDD\|226911	COG4536, CorB, Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism].	2.157e-159
NZ_CP040229.1\|WP_000168845.1\|827347_828109_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP040229.1\|WP_001074405.1\|831475_832873_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP040229.1\|WP_001065802.1\|821834_822131_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	3.92494e-14
NZ_CP040229.1\|WP_001183849.1\|826168_827020_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	2.68358e-76
NZ_CP040229.1\|WP_000290492.1\|819315_819696_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.19798e-69
NZ_CP040229.1\|WP_138766945.1\|824111_824933_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.51141e-112

>NZ_CP040229.1|WP_138742457.1|825091_825313_-|hypothetical-protein
MYTGFPSASMLGPTPTCTVYKISFRNPLCWGPAIIVKRLLQSYFHSINNCLYNIVNLWTLIEITEAYRPSLYI
>NZ_CP040229.1|WP_138766945.1|824111_824933_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGSKSGSDDKKITVGASPAPHAEILEKAKPLLDKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGNVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP040229.1|WP_138766944.1|823398_824094_+|ABC-transporter-permease-subunit
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILFIVFIIQFIGDWLTNKLDKR
>NZ_CP040229.1|WP_000571213.1|822380_823406_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP040229.1|WP_001065802.1|821834_822131_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFQSVTDLLENLK
>NZ_CP040229.1|WP_001018957.1|821455_821842_+|hypothetical-protein
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKFDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPFLPNINNERLVLVNE
>NZ_CP040229.1|WP_000932205.1|819875_820754_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPILPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPISDLSLKDIQAHLKSLNADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQGLKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP040229.1|WP_000662306.1|819760_819874_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>NZ_CP040229.1|WP_000290492.1|819315_819696_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEVSDESQLEALLSAEKYAEMIGE
>NZ_CP040229.1|WP_000589549.1|818801_819158_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP040229.1|WP_000752917.1|825740_825935_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP040229.1|WP_001183849.1|826168_827020_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEFVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP040229.1|WP_000168845.1|827347_828109_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP040229.1|WP_000205572.1|828207_829515_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP040229.1|WP_000807673.1|829629_830871_+|cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSTIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
>NZ_CP040229.1|WP_001010508.1|830860_831325_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MNFNNLDQLYRSVIMDHYKNPRNKGVLDNGSMTVDMNNPTCGDRIRLTFDIEDGIIKDAKFEGEGCSISMASASMMTQAVKGHSLGEAMQMSQEFTKMMLGEDYVITEEMGDIEALQGVSQFPARIKCATLAWKALEKGTVAKEGKAEGTTEEE
>NZ_CP040229.1|WP_001074405.1|831475_832873_+|Fe-S-cluster-assembly-protein-SufB
MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEPEWMLDFRLKSLKLFYKMPMPQWGGDLSELNFDDITYYVKPSEQAERSWDEVPEEIKRTFDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKYFASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLIIADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRTFVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHKAPNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYNEVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
>NZ_CP040229.1|WP_000274033.1|833204_833519_-|hypothetical-protein
MYFVLAIFTIISASVSLGYSIQACASSHNINAYYALSRSLPLFLLAIFSLVIHSAIFLITISIAMILVQFLDAIVGYKSNDVFKTYGPLATSVVNLILLIVFLF
>NZ_CP040229.1|WP_138766946.1|833887_834928_+|DUF21-domain-containing-protein
MIIAIIILIFISFFFSGSETALTAANKTKFKTEADKGDKKAKGIVKLLEKPSEFITTILIGNNVANILLPTLVTIMALCWGISVGIASAVLTVVIILISEVIPKSVAATFPDKITRLVYPIINICVIVFRPITLLLNKLTDSINRCLSKGQPQEHQFSKEEFKTMLAIAGHEGALNEIETSRLEGVINFENLKVKDVDTTPRINVTAFASNATYEEVYETVMNKPYTRYPVYEGDIDNIIGVFHSKYLLAWSNKKEDQITNYSAKPLFVNEHNKAEWVLRKMTISRKHLAIVLDEFGGTEAIVSHEDLIEELLGMEIEDEMDKKEKEKLSQQQIQFQQRKNRNVSI
>NZ_CP040229.1|WP_000267231.1|834941_836009_+|nitronate-monooxygenase
MWNKNRLTQMLSIEFPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSNQIENMNAWLKPYRRALHLEEPVVKITEEQQFKCHIDTIIKKQVPVCCFTFGIPNESIIKRLKEANIKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVITKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK

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Crispr_ID: NZ_CP040229_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_5

1720676-1720762

Orphan

Consensus_repeat	Method
TGCAAGTTGGGGTGGGGCCCCAACATAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_5

>merge|NZ_CP040229|5|1720676-1720762|CRISPRCasFinder
TGCAAGTTGGGGTGGGGCCCCAACATAGAAGGTGACGTAATGTCAGCTTACTTTAATGTGCAAGTTGGGCTGGGGCCCCAACATAGA

>NZ_CP040229|5|5|1720676-1720762|CRISPRCasFinder
TGCAAGTTGGGGTGGGGCCCCAACATAGA	AGGTGACGTAATGTCAGCTTACTTTAATG
TGCAAGTTGGGCTGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_000277602.1\|1722356_1722770_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP040229.1\|WP_000626092.1\|1719542_1720484_-\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_CP040229.1\|WP_000829167.1\|1706460_1707582_-\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NZ_CP040229.1\|WP_000471571.1\|1713594_1714452_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP040229.1\|WP_000717561.1\|1711413_1712382_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_CP040229.1\|WP_000226933.1\|1716324_1719522_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NZ_CP040229.1\|WP_001232654.1\|1709634_1711392_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_CP040229.1\|WP_000690004.1\|1725510_1726629_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP040229.1\|WP_000365308.1\|1730468_1731239_-\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|182593
NZ_CP040229.1\|WP_000777188.1\|1723275_1723965_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_CP040229.1\|WP_000136251.1\|1729876_1730371_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP040229.1\|WP_000058389.1\|1714646_1715876_-\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NZ_CP040229.1\|WP_000840583.1\|1728806_1729754_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NZ_CP040229.1\|WP_000160430.1\|1720853_1722152_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_CP040229.1\|WP_000161656.1\|1724139_1725195_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NZ_CP040229.1\|WP_000634175.1\|1726769_1727270_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP040229.1\|WP_000818532.1\|1707929_1709291_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP040229.1\|WP_000040067.1\|1727516_1728719_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP040229.1\|WP_000883646.1\|1712650_1713595_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_CP040229.1\|WP_000123161.1\|1705143_1706412_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_000277602.1\|1722356_1722770_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.00154e-19
NZ_CP040229.1\|WP_000626092.1\|1719542_1720484_-\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	5.72376e-100
NZ_CP040229.1\|WP_000829167.1\|1706460_1707582_-\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NZ_CP040229.1\|WP_000471571.1\|1713594_1714452_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP040229.1\|WP_000717561.1\|1711413_1712382_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_CP040229.1\|WP_000226933.1\|1716324_1719522_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NZ_CP040229.1\|WP_001232654.1\|1709634_1711392_-\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_CP040229.1\|WP_000690004.1\|1725510_1726629_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP040229.1\|WP_000365308.1\|1730468_1731239_-\|TSUP-family-transporter	gnl\|CDD\|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	1.0657e-38
NZ_CP040229.1\|WP_000777188.1\|1723275_1723965_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	3.09103e-133
NZ_CP040229.1\|WP_000136251.1\|1729876_1730371_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	7.99696e-100
NZ_CP040229.1\|WP_000058389.1\|1714646_1715876_-\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_CP040229.1\|WP_000840583.1\|1728806_1729754_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	6.63876e-57
NZ_CP040229.1\|WP_000160430.1\|1720853_1722152_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_CP040229.1\|WP_000161656.1\|1724139_1725195_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	1.16164e-126
NZ_CP040229.1\|WP_000634175.1\|1726769_1727270_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NZ_CP040229.1\|WP_000818532.1\|1707929_1709291_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP040229.1\|WP_000040067.1\|1727516_1728719_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP040229.1\|WP_000883646.1\|1712650_1713595_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_CP040229.1\|WP_000123161.1\|1705143_1706412_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0

>NZ_CP040229.1|WP_000626092.1|1719542_1720484_-|pApA-hydrolase-Pde2
MISTMNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLKQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVNSWDEFEQLAKALRTKLN
>NZ_CP040229.1|WP_000226933.1|1716324_1719522_-|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDTCIANNIKPIFGMTIYVTNGLNTVETVVLAKDNNGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKNVADEHRDIVQVFDSHEDTYLDHRSVLVQGIKHVWIQDVCYQTRHDADTISALAAIRDNTKLDLIHDQEDFGAHFLTENEIQQLDVNPEYFTQADRIAQKCDAELKYHQSLLPQYQAPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRREKVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVEERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDLRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVVLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_CP040229.1|WP_000058389.1|1714646_1715876_-|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_CP040229.1|WP_000471571.1|1713594_1714452_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
>NZ_CP040229.1|WP_000883646.1|1712650_1713595_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVEQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_CP040229.1|WP_000717561.1|1711413_1712382_-|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_CP040229.1|WP_001232654.1|1709634_1711392_-|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIEEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_CP040229.1|WP_000818532.1|1707929_1709291_+|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAYKTQFGHASFTNLYEHGVFPKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKKATYKLFGGKYMGYLIFVFFIFVFGLLFINVETRRAIYFIPIWFILLGFMYLRYKRIAAKSNN
>NZ_CP040229.1|WP_000829167.1|1706460_1707582_-|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NZ_CP040229.1|WP_000123161.1|1705143_1706412_-|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVEKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALTEFGDQVFTWQQYDEIVEKEGRDAANVAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
>NZ_CP040229.1|WP_000160430.1|1720853_1722152_-|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVIDFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANQTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_CP040229.1|WP_000277602.1|1722356_1722770_+|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_CP040229.1|WP_000777188.1|1723275_1723965_-|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_CP040229.1|WP_000161656.1|1724139_1725195_+|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEINKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSQEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_CP040229.1|WP_000690004.1|1725510_1726629_-|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDNPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_CP040229.1|WP_000634175.1|1726769_1727270_+|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_CP040229.1|WP_000040067.1|1727516_1728719_-|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVDGEKVKTVQDIKDHVEAVDIMLDAFKKHNIINDINDIDGTGHRVVHGGEKFPESAAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLQRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTYGGLK
>NZ_CP040229.1|WP_000840583.1|1728806_1729754_-|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEADIVIGDFPVGYYPIDERSRDFKLGFEEGHSYSHYLLIEQAINALKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK
>NZ_CP040229.1|WP_000136251.1|1729876_1730371_-|thiol-peroxidase
MTEITFKGGPIHLKGQLINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI
>NZ_CP040229.1|WP_000365308.1|1730468_1731239_-|TSUP-family-transporter
MDLNLTMIIIIILFGFIAAFIDSVVGGGGLISTPALLAIGLPPSVALGTNKLASSFGSLTSAIKFIRSGKVDLYVVAKLFGFVFLASACGAYIATMVPSQILKPLIIIALSSVFIFTLLKKDWGNTRTFTQFTFKKAILFAALFILIGFYDGFVGGGTGSFMLFVLLIFGFDFLSAAGNAKVLNFASNIGALVLFMVLGQVDYVIGLVMAASMIVGSYAGAHFAIKQGVGYVKVLFIIITAILILKNAFDYIQQFV

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Crispr_ID: NZ_CP040229_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_6

1723096-1723178

Orphan

Consensus_repeat	Method
GAAGCTGACGAAAAAGTCAGCTTAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_6

>merge|NZ_CP040229|6|1723096-1723178|CRISPRCasFinder
GAAGCTGACGAAAAAGTCAGCTTACTATAATGTGCAAGTTGGGGTGGGCCCCAACACAGAAGCTGACGAAAAAGTCAGCTTAC

>NZ_CP040229|6|6|1723096-1723178|CRISPRCasFinder
GAAGCTGACGAAAAAGTCAGCTTAC	TATAATGTGCAAGTTGGGGTGGGCCCCAACACA
GAAGCTGACGAAAAAGTCAGCTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_000277602.1\|1722356_1722770_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP040229.1\|WP_000626092.1\|1719542_1720484_-\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_CP040229.1\|WP_000690004.1\|1725510_1726629_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP040229.1\|WP_138767044.1\|1732505_1733654_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|224029
NZ_CP040229.1\|WP_000471571.1\|1713594_1714452_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP040229.1\|WP_000717561.1\|1711413_1712382_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_CP040229.1\|WP_000226933.1\|1716324_1719522_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NZ_CP040229.1\|WP_001232654.1\|1709634_1711392_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_CP040229.1\|WP_000040067.1\|1727516_1728719_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP040229.1\|WP_000365308.1\|1730468_1731239_-\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|182593
NZ_CP040229.1\|WP_000634175.1\|1726769_1727270_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP040229.1\|WP_000872673.1\|1731282_1732506_-\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234960
NZ_CP040229.1\|WP_000136251.1\|1729876_1730371_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP040229.1\|WP_000777188.1\|1723275_1723965_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_CP040229.1\|WP_000840583.1\|1728806_1729754_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NZ_CP040229.1\|WP_000160430.1\|1720853_1722152_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_CP040229.1\|WP_000161656.1\|1724139_1725195_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NZ_CP040229.1\|WP_000818532.1\|1707929_1709291_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP040229.1\|WP_000883646.1\|1712650_1713595_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_CP040229.1\|WP_000058389.1\|1714646_1715876_-\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_000277602.1\|1722356_1722770_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.00154e-19
NZ_CP040229.1\|WP_000626092.1\|1719542_1720484_-\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	5.72376e-100
NZ_CP040229.1\|WP_000690004.1\|1725510_1726629_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP040229.1\|WP_138767044.1\|1732505_1733654_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	9.48636e-165
NZ_CP040229.1\|WP_000471571.1\|1713594_1714452_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP040229.1\|WP_000717561.1\|1711413_1712382_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_CP040229.1\|WP_000226933.1\|1716324_1719522_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NZ_CP040229.1\|WP_001232654.1\|1709634_1711392_-\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_CP040229.1\|WP_000040067.1\|1727516_1728719_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP040229.1\|WP_000365308.1\|1730468_1731239_-\|TSUP-family-transporter	gnl\|CDD\|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	1.0657e-38
NZ_CP040229.1\|WP_000634175.1\|1726769_1727270_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NZ_CP040229.1\|WP_000872673.1\|1731282_1732506_-\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	0
NZ_CP040229.1\|WP_000136251.1\|1729876_1730371_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	7.99696e-100
NZ_CP040229.1\|WP_000777188.1\|1723275_1723965_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	3.09103e-133
NZ_CP040229.1\|WP_000840583.1\|1728806_1729754_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	6.63876e-57
NZ_CP040229.1\|WP_000160430.1\|1720853_1722152_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_CP040229.1\|WP_000161656.1\|1724139_1725195_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	1.16164e-126
NZ_CP040229.1\|WP_000818532.1\|1707929_1709291_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP040229.1\|WP_000883646.1\|1712650_1713595_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_CP040229.1\|WP_000058389.1\|1714646_1715876_-\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0

>NZ_CP040229.1|WP_000277602.1|1722356_1722770_+|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_CP040229.1|WP_000160430.1|1720853_1722152_-|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVIDFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANQTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_CP040229.1|WP_000626092.1|1719542_1720484_-|pApA-hydrolase-Pde2
MISTMNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLKQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVNSWDEFEQLAKALRTKLN
>NZ_CP040229.1|WP_000226933.1|1716324_1719522_-|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDTCIANNIKPIFGMTIYVTNGLNTVETVVLAKDNNGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKNVADEHRDIVQVFDSHEDTYLDHRSVLVQGIKHVWIQDVCYQTRHDADTISALAAIRDNTKLDLIHDQEDFGAHFLTENEIQQLDVNPEYFTQADRIAQKCDAELKYHQSLLPQYQAPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRREKVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVEERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDLRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVVLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_CP040229.1|WP_000058389.1|1714646_1715876_-|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_CP040229.1|WP_000471571.1|1713594_1714452_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
>NZ_CP040229.1|WP_000883646.1|1712650_1713595_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVEQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_CP040229.1|WP_000717561.1|1711413_1712382_-|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_CP040229.1|WP_001232654.1|1709634_1711392_-|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIEEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_CP040229.1|WP_000818532.1|1707929_1709291_+|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAYKTQFGHASFTNLYEHGVFPKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKKATYKLFGGKYMGYLIFVFFIFVFGLLFINVETRRAIYFIPIWFILLGFMYLRYKRIAAKSNN
>NZ_CP040229.1|WP_000777188.1|1723275_1723965_-|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_CP040229.1|WP_000161656.1|1724139_1725195_+|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEINKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSQEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_CP040229.1|WP_000690004.1|1725510_1726629_-|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDNPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_CP040229.1|WP_000634175.1|1726769_1727270_+|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_CP040229.1|WP_000040067.1|1727516_1728719_-|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVDGEKVKTVQDIKDHVEAVDIMLDAFKKHNIINDINDIDGTGHRVVHGGEKFPESAAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLQRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTYGGLK
>NZ_CP040229.1|WP_000840583.1|1728806_1729754_-|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEADIVIGDFPVGYYPIDERSRDFKLGFEEGHSYSHYLLIEQAINALKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK
>NZ_CP040229.1|WP_000136251.1|1729876_1730371_-|thiol-peroxidase
MTEITFKGGPIHLKGQLINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI
>NZ_CP040229.1|WP_000365308.1|1730468_1731239_-|TSUP-family-transporter
MDLNLTMIIIIILFGFIAAFIDSVVGGGGLISTPALLAIGLPPSVALGTNKLASSFGSLTSAIKFIRSGKVDLYVVAKLFGFVFLASACGAYIATMVPSQILKPLIIIALSSVFIFTLLKKDWGNTRTFTQFTFKKAILFAALFILIGFYDGFVGGGTGSFMLFVLLIFGFDFLSAAGNAKVLNFASNIGALVLFMVLGQVDYVIGLVMAASMIVGSYAGAHFAIKQGVGYVKVLFIIITAILILKNAFDYIQQFV
>NZ_CP040229.1|WP_000872673.1|1731282_1732506_-|tRNA-4-thiouridine(8)-synthase-ThiI
MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVKGKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTLEAMSATAIKFAQQFEENSTFKIDVKRADKNYPMDTYELQRELGGAVLKHFDNISVNVKRPDHEIRVEVRLDAIYMYEEVVQGAGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQAKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLVHQIGAYAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTFETSIQPFEDCCTIFTPKNPVTEPNFDKVVQYESVFDFEEMINRAVENIETLEITSDYKTIKEQQTNQLINDFL
>NZ_CP040229.1|WP_138767044.1|1732505_1733654_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MFILIYLDNAATTKAFEEVLDTYLKVNQSMYYNPNSPHKAGLQADQLLQQAKVQINDMVNTNMTYDVVFTSGATESNNIALKGVAYRKFDTAREIITSVLEHPSVLEVVRYLEEREGFKVKYVDVTKDGSINLEHFKELMSDKVGLVTCMYVNNVTGQIQPIPQMADVIKNYPKAHFHVDAVQAFGKISMDFNNVDSISLSGHKFNGLKGQGVLLVNHIQNVEPTVHGGGQEYGVRSGTVNLPNDIAMVKAMKIANENLEALNAFVTELNNDVRQFLNKYHGVYINSSTSGSPFVLNVSFPSVKGEVLVNAFSKYDIMISTTSACSSKRNKLNEVLTAMGLSDKAIEGSIRLSFGAMTTKEDITKFKETFTIIYEEIKELLK

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Crispr_ID: NZ_CP040229_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_7

2086545-2086757

Orphan

Consensus_repeat	Method
TGATGTGCTGTTGTGGAAGCTTGGTGTCGTGCCATGCTACTTTGATG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP040229_7

>merge|NZ_CP040229|7|2086545-2086757|CRISPRCasFinder
TGACGTATTGTTGCGGGAACTTGGTGTCATGACATGTTACTTTGATGTGCTGGTACCACGATGCGTCTTGATGTAGTGCTATGATGTGCTGTTGTGGAAGCTTGGTGTCGTGCCATGCTACTTTGATGTGCTGTTGTGGGAGCTTGGTGTTGGTGCCATGTTACTTTGATGTGCTGTTGTGGAAGCTTGGTGTCATGCCATGCTACTTTGATG

>NZ_CP040229|7|7|2086545-2086757|CRISPRCasFinder
TGACGTATTGTTGCGGGAACTTGGTGTCATGACATGTTACTTTGATG	TGCTGGTACCACGATGCGTCTTGATGTAGTGCTA
TGATGTGCTGTTGTGGAAGCTTGGTGTCGTGCCATGCTACTTTGATG	TGCTGTTGTGGGAGCTTGGTGTTGGTGCCATGTTACTT
TGATGTGCTGTTGTGGAAGCTTGGTGTCATGCCATGCTACTTTGATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_000447678.1\|2095197_2095638_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP040229.1\|WP_001789631.1\|2094637_2095141_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379494
NZ_CP040229.1\|WP_000594965.1\|2091128_2091959_-\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|180561
NZ_CP040229.1\|WP_138767008.1\|2079196_2080552_-\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl\|CDD\|223841
NZ_CP040229.1\|WP_000396068.1\|2091951_2092641_-\|thiaminase-II	unknown	unknown	gnl\|CDD\|213919
NZ_CP040229.1\|WP_000932694.1\|2094111_2094507_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|366099
NZ_CP040229.1\|WP_001825748.1\|2086790_2087111_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_001109939.1\|2081954_2083157_+\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP040229.1\|WP_000828354.1\|2083420_2083558_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000159641.1\|2080566_2081637_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234993
NZ_CP040229.1\|WP_000483161.1\|2089710_2090352_-\|thiamine-phosphate-synthase	unknown	unknown	gnl\|CDD\|234590
NZ_CP040229.1\|WP_000138932.1\|2083906_2084200_-\|copper-sensing-transcriptional-repressor-CsoR	unknown	unknown	gnl\|CDD\|197387
NZ_CP040229.1\|WP_000571550.1\|2084365_2085850_+\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|211988
NZ_CP040229.1\|WP_000581792.1\|2083685_2083895_-\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|238219
NZ_CP040229.1\|WP_001190840.1\|2076112_2076808_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP040229.1\|WP_001178939.1\|2077160_2078681_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587
NZ_CP040229.1\|WP_000751995.1\|2093027_2093723_-\|lytic-transglycosylase-SceD	unknown	unknown	gnl\|CDD\|369056
NZ_CP040229.1\|WP_000725800.1\|2088752_2089625_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NZ_CP040229.1\|WP_000072261.1\|2073455_2076113_+\|sensor-histidine-kinase-KdpD	unknown	unknown	gnl\|CDD\|225115
NZ_CP040229.1\|WP_001108486.1\|2090353_2091145_-\|hydroxyethylthiazole-kinase	unknown	unknown	gnl\|CDD\|236477

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_000447678.1\|2095197_2095638_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	8.27669e-92
NZ_CP040229.1\|WP_001789631.1\|2094637_2095141_+\|hypothetical-protein	gnl\|CDD\|379494	pfam14183, YwpF, YwpF-like protein. The YwpF-like protein family includes the B. subtilis YwpF protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 146 and 167 amino acids in length. There is a conserved IIN sequence motif.	5.66466e-57
NZ_CP040229.1\|WP_000594965.1\|2091128_2091959_-\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|180561	PRK06427, PRK06427, bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed.	1.38659e-148
NZ_CP040229.1\|WP_138767008.1\|2079196_2080552_-\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl\|CDD\|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	0
NZ_CP040229.1\|WP_000396068.1\|2091951_2092641_-\|thiaminase-II	gnl\|CDD\|213919	TIGR04306, salvage_TenA, thiaminase II. The TenA protein of Bacillus subtilis and Staphylococcus aurues, and the C-terminal region of trifunctional protein Thi20p from Saccharomyces cerevisiae, perform cleavages on thiamine and related compounds to produce 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP), a substrate a salvage pathway for thiamine biosynthesis. The gene symbol tenA, for Transcription ENhancement A, reflects a misleading early characterization as a regulatory protein. This family is related to PqqC from the PQQ biosynthesis system (see TIGR02111), heme oxygenase (pfam01126), and CADD (Chlamydia protein Associating with Death Domains), a putative folate metabolism enzyme (see TIGR04305).	1.05378e-100
NZ_CP040229.1\|WP_000932694.1\|2094111_2094507_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|366099	pfam00436, SSB, Single-strand binding protein family. This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.	9.06157e-32
NZ_CP040229.1\|WP_000725800.1\|2088752_2089625_-\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	7.06711e-64
NZ_CP040229.1\|WP_001109939.1\|2081954_2083157_+\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.51677e-108
NZ_CP040229.1\|WP_000159641.1\|2080566_2081637_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	0
NZ_CP040229.1\|WP_000483161.1\|2089710_2090352_-\|thiamine-phosphate-synthase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	5.71532e-89
NZ_CP040229.1\|WP_000138932.1\|2083906_2084200_-\|copper-sensing-transcriptional-repressor-CsoR	gnl\|CDD\|197387	cd10152, SaCsoR-like_DUF156, Staphylococcus aureus copper-sensitive operon repressor (CsoR), and related domains; this family was previously known as part of DUF156. This domain family includes Staphylococcus aureus CsoR (SaCsoR). SaCsoR is Cu(I)-inducible, and regulates the expression of genes involved in copper homeostasis; it represses a genetically unlinked copA-copZ operon. copA encodes a copper efflux P-type ATPase, and copZ, a copper chaperone. This family belongs to a larger superfamily that contains various transcriptional regulators that respond to different stressors such as Cu(I), Ni(I), sulfite, and formaldehyde, and includes Mycobacterium tuberculosis CsoR (MtCsoR), Bacillus subtilis CsoR, and Thermus thermophilus CsoR. The latter three proteins do not belong to this family. CsoRs form homotetramers (dimer of dimers). In MtCsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in the majority of members of this superfamily, including this family, and a conserved Tyr and a Glu residue that facilitate allosteric regulation of DNA binding for CsoRs are also well conserved.	8.02331e-35
NZ_CP040229.1\|WP_000571550.1\|2084365_2085850_+\|cardiolipin-synthase	gnl\|CDD\|211988	TIGR04265, bac_cardiolipin, cardiolipin synthase. This model is based on experimentally characterized bacterial cardiolipin synthases (cls) from E. coli, Staphylococcus aureus (two), and Bacillus pseudofirmus OF4. This model describes just one of several homologous but non-orthologous forms of cls. The cutoff score is set arbitrarily high to avoid false-positives. Note that there are two enzymatic activites called cardiolipin synthase. This model represents type 1, which does not rely on a CDP-linked donor, but instead does a reversible transfer of a phosphatidyl group from one phosphatidylglycerol molecule to another.	0
NZ_CP040229.1\|WP_000581792.1\|2083685_2083895_-\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|238219	cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. In the case of copper, stoichiometry of binding is one Cu+ ion per binding domain. Repeats of the HMA domain in copper chaperone has been associated with Menkes/Wilson disease due to binding of multiple copper ions.	0.000383249
NZ_CP040229.1\|WP_001190840.1\|2076112_2076808_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.28552e-68
NZ_CP040229.1\|WP_001178939.1\|2077160_2078681_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	7.40342e-159
NZ_CP040229.1\|WP_000751995.1\|2093027_2093723_-\|lytic-transglycosylase-SceD	gnl\|CDD\|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	6.44668e-24
NZ_CP040229.1\|WP_000072261.1\|2073455_2076113_+\|sensor-histidine-kinase-KdpD	gnl\|CDD\|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP040229.1\|WP_001108486.1\|2090353_2091145_-\|hydroxyethylthiazole-kinase	gnl\|CDD\|236477	PRK09355, PRK09355, hydroxyethylthiazole kinase; Validated.	7.69146e-123

>NZ_CP040229.1|WP_000571550.1|2084365_2085850_+|cardiolipin-synthase
MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANSIWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENFSNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQYYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFFPSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGDAVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGYLKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKNAASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQIAKKLKQAFIDDLAVSSELTKARYANRSLWIKFKEGISQLLSPIL
>NZ_CP040229.1|WP_000138932.1|2083906_2084200_-|copper-sensing-transcriptional-repressor-CsoR
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVAIKLLEQHMKSCIMNKVNQGAQEEAMEELLVTFQKLIKD
>NZ_CP040229.1|WP_000581792.1|2083685_2083895_-|heavy-metal-associated-domain-containing-protein
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
>NZ_CP040229.1|WP_000828354.1|2083420_2083558_-|hypothetical-protein
MKRPEKIQNVVKLLSSLGVNIKKTKSRLDIINTLPASNKVSHELK
>NZ_CP040229.1|WP_001109939.1|2081954_2083157_+|rod-shape-determining-protein-RodA
MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQYSANFGIRQIFYYILGAIFAGIIMFISPKKIKHYTYLLYFLICLLLIGLLVIPESPITPIINGAKSWYTFGPISIQPSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKIIGVSLVPSILILLQNDLGTTLVLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGILYAPALIENLLGVQLYQMGRINSWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHGEVYIPENHTDFIFSVIGEELGFIGSVILILIFLFLIFHLIRLAAKIEDQFNKIFIVGFVTLLVFHILQNIGMTIQLLPITGIPLPFISYGGSALWSMMTGIGIVLSIYYHEPKRYVDLYHPKSN
>NZ_CP040229.1|WP_000159641.1|2080566_2081637_-|D-alanine--D-alanine-ligase
MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITTEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELAKERHQDKQKNKYKID
>NZ_CP040229.1|WP_138767008.1|2079196_2080552_-|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MINVTLKQIQSWIPCEIEDQFLNQEINGVTIDSRAISKNMLFIPFKGENVDGHRFVSKALQDGAGAAFYQKGTPIDENVSGPIIWVEDTLTALQQLAQVYLRHVNPKVIAVTGSNGKTTTKDMIESVLHTEFKVKKTQGNYNNEIGLPLTILELDNDTEISILEMGMSGFHEIEFLSNLAQPDIAVITNIGESHMQDLGSREGIAKAKSEITIGLKDNGTFIYDGDEPLLKPHVKEVENAKCISIGVATDNALVCSVDDRDTTGISFTINNEHYDLPILGKHNMKNATIAIAVGHELGLTYNIIYQNLKNVSLTGMRMEQHTLENDITVINDAYNASPTSMRAAIDTLSTLTGRRILILGDVLELGENSKEMHIGVGNYLEEKHIDVLYTFGNEAKYIYDSGQQHVEKAQHFNSKDDMIEVLTSDLKAHDRVLVKGSRGMKLEEVVNALIS
>NZ_CP040229.1|WP_001178939.1|2077160_2078681_-|DEAD/DEAH-box-helicase
MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIEKVVGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALKKGPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQTMLFSATMPKAIQALVQQFMKSPKIIKTMNNEMSDPQIEEFYTIVKELEKFDTFTNFLDVHQPELAIVFGRTKRRVDELTSALISKGYKAEGLHGDITQAKRLEVLKKFKNDQINILVATDVAARGLDISGVSHVYNFDIPQDTESYTHRIGRTGRAGKEGIAVTFVNPIEMDYIRQIEDANGRKMSALRPPHRKEVLQAREDDIKEKVENWMSKDSESRLKRISTELLNEYNDVDLVAALLQELVEANDEVEVQLTFEKPLSRKGRNGKPSGSRNRNSKRGNPKFDSKSKRSKGYSSKKKSTKKFDRKEKSSGGSRPMKGRTFADHQK
>NZ_CP040229.1|WP_001190840.1|2076112_2076808_+|response-regulator-transcription-factor
MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQIDKPDVILLDLGLPDKDGLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTKPFNVDELRARIRVIERIAKSHQETNFVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSLLELLSNHKGKVLTYEMILKRIYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTHPRIGYQMLQWKEK
>NZ_CP040229.1|WP_000072261.1|2073455_2076113_+|sensor-histidine-kinase-KdpD
MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNVDIKIGYIEPHQRDETNALAEQLLKIATNFTKHGSHHFQYLDVDRIIEESPTIVLIDELAHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIERMTGVHVKERVPDYFIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYAHLSELRTLTLRTVADLMSDKEKVRHNHKTSLKPHIAVAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEISRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKRRDFFNKPLIDHLMSFEHSYNIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMILIQIICVMMGLWIYQLDKHESSTIILMIFLIGIILLSIWTRSYIIGFLAAIINVFVFNYFFTEPRYTFEVYRFDYPITFIVSILTSILTSALLKQIKFQYAITKKQLYRTDLLFQFNDSIKQTYTVENLLINAGYQINQLLQQSITIYVINQSKVIKTIPLQNHIDNTTQQHEQALSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESMLNELSLAVENVTLLKQTRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSHSKDMSIIEKEQLLVHSFQESQYLYLLVTNILSLTKLQSSNVQIKLQPYLVSELVEEIDMILERRHLKKRITVSSSVDLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYASDEQIEFAVIDEGPGISLKEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKHQSNLQYKPNQPHGSIFYFNIDTDFNEGDI
>NZ_CP040229.1|WP_001825748.1|2086790_2087111_+|hypothetical-protein
MIWRCGVMGGIARGIDAMPLQFYDMALGRCNVYYAVVTLLFHTVTCICELLWKCCDIYCYTDESLCQDDIAMMNSNSVINHFLHAEISLILFGSMSNWTDAFNIGS
>NZ_CP040229.1|WP_000725800.1|2088752_2089625_-|membrane-protein-insertase-YidC
MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVDGLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGNNKKGKNTQVVSKKKKK
>NZ_CP040229.1|WP_000483161.1|2089710_2090352_-|thiamine-phosphate-synthase
MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREKGESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIAQYFTDKIIGLSISDLGEYAKSDLTHVDYIGVGPIYPTPSKNDAHTPVGPEMIATFKEMNPQLPIVAIGGINTSNVAPIVEAGANGISVISAISKSENIEKTVNRFKDFFNN
>NZ_CP040229.1|WP_001108486.1|2090353_2091145_-|hydroxyethylthiazole-kinase
MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPEEAEEFYKVAQALLINIGTLTAQNEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFCKLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDANLDAVAIAKKAYAIYKTAIVITGKEDVIVQGDKAIVLANGSPLLARVTGAGCLLGGVIAGFLFRETEPDIEALIEAVSVFNIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRIRIQEVE
>NZ_CP040229.1|WP_000594965.1|2091128_2091959_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MIKPKIALTIAGTDPTGGAGVMADLKSFHSCGVYGMGVVTSIVAQNTLGVQNIHNLNHQWVDEQLDSVFNDTLPHAIKTGMIATADTMETIRHYLMQHESIPYVIDPVMLAKSGDSLMDNDTKQNLQHTLLPLADVVTPNLPEAEEITGLTIDSEEKIMQAGRIFINEIGSKGVIVKGGHSNDTDIAKDYLFTKEGVQTFENERFKTKHTHGTGCTFSAVITAELAKGRPLFDAVQKAKKFISMSIQYTPEIGRGRGPVNHFAYLKKEGLDDELSK
>NZ_CP040229.1|WP_000396068.1|2091951_2092641_-|thiaminase-II
MEFSQKLYQAAKPIINDIYEDDFIQKMLLGNIQADALRHYLQADAAYLKEFTNLYALLIPKMNSMNDVKFLVEQIEFMVEGEVLAHDILAQIVGESYEEIIKTKVWPPSGDHYIKHMYFQAHSRENAIYTIAAMAPCPYIYAELAKRSQSDHKLNREKDTAKWFDFYSTEMDDIINVFESLMNKLAESMSDKELEQVKQVFLESCIHERRFFNMAMTLEQWEFGGKVND
>NZ_CP040229.1|WP_000751995.1|2093027_2093723_-|lytic-transglycosylase-SceD
MKKTLLASSLAVGLGIVAGNAGHEAHASEADLNKASLAQMAQSNDQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGANGADMSAQAPATNNVAPSADQANQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKASEGSSVNVNDHLKQIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVKLYNTGGAGHWVTA
>NZ_CP040229.1|WP_000932694.1|2094111_2094507_-|single-stranded-DNA-binding-protein
MLNKIVIVGRLTKDAQIFEKEDRKIATFCVATHRNYKDENGEIVCDYLFCKAFGKLASNIEKYTNQGTLVGITGQMRSRKYDKDGQTHFVTELYVETIKFMSPKSQNNEILSDSILDIDSQNIDNHDLLEI
>NZ_CP040229.1|WP_001789631.1|2094637_2095141_+|hypothetical-protein
MTLNLLNNSKIINIKLMGCGNMKTFKAVRFQIVNEHGRIIEYELEDGVIINKEESGTGWLLEIVISNEHYETFKEYQDNEQLLDIRVVITRPANDPALFESTVKSIKNFKTTMSIVFECHIYTLRQQYAESLLEQLIDDGLSGEELKKSFNRMMQSKPKLKDEKLEE
>NZ_CP040229.1|WP_000447678.1|2095197_2095638_-|3-hydroxyacyl-ACP-dehydratase-FabZ
METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGNEPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVPGDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK

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Crispr_ID: NZ_CP040229_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_8

2143250-2143400

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3,TnsE_C

The CRISPR arrays of NZ_CP040229_8

>merge|NZ_CP040229|8|2143250-2143400|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTAAGGGGCTCTTATGCAGTTGATGCATAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGAGCTTCTTTCTA

>NZ_CP040229|8|8|2143250-2143400|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTAAGGGGCTCTTATGCA	GTTGATGCATAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGAGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_001024099.1\|2139755_2140421_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP040229.1\|WP_001127960.1\|2138383_2139322_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP040229.1\|WP_000495673.1\|2142140_2143232_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_001156920.1\|2151032_2151437_-\|hypothetical-protein	TnsE_C	TnsE	gnl\|CDD\|376049
NZ_CP040229.1\|WP_001123309.1\|2135206_2135620_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP040229.1\|WP_001792291.1\|2144266_2144449_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000101714.1\|2147326_2147935_-\|TIR-domain-containing-protein	unknown	unknown	gnl\|CDD\|378100
NZ_CP040229.1\|WP_001802298.1\|2143729_2143834_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000876896.1\|2147962_2148997_-\|toll/interleukin-1-receptor-domain-containing-protein	unknown	unknown	gnl\|CDD\|379328
NZ_CP040229.1\|WP_000123402.1\|2136077_2137451_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP040229.1\|WP_099184063.1\|2150617_2150908_-\|DUF3387-domain-containing-protein	unknown	unknown	gnl\|CDD\|378743
NZ_CP040229.1\|WP_000003759.1\|2140572_2140893_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP040229.1\|WP_000808818.1\|2138122_2138353_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000019735.1\|2140894_2141875_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP040229.1\|WP_000160304.1\|2133732_2134443_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP040229.1\|WP_000220902.1\|2145107_2145200_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000070865.1\|2134563_2135007_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP040229.1\|WP_000370942.1\|2145329_2146187_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP040229.1\|WP_001792784.1\|2144513_2144672_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000908191.1\|2146254_2147037_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_001024099.1\|2139755_2140421_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	7.27205e-48
NZ_CP040229.1\|WP_001127960.1\|2138383_2139322_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP040229.1\|WP_000876896.1\|2147962_2148997_-\|toll/interleukin-1-receptor-domain-containing-protein	gnl\|CDD\|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	2.54926e-06
NZ_CP040229.1\|WP_001156920.1\|2151032_2151437_-\|hypothetical-protein	gnl\|CDD\|376049	pfam18623, TnsE_C, TnsE C-terminal domain. The bacterial transposon Tn7 facilitates horizontal transfer by directing transposition into actively replicating DNA with the element-encoded protein TnsE. Structural analysis of the C-terminal domain of TnsE identified a central V-shaped loop that toggles between two distinct conformations. It is suggested that a conformational change within the C-terminal domain of TnsE underlies target site selection by regulating stable engagement of the target DNA while providing a signal for activating transposition.	5.43167e-08
NZ_CP040229.1\|WP_001123309.1\|2135206_2135620_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	5.06041e-44
NZ_CP040229.1\|WP_000908191.1\|2146254_2147037_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.99209e-106
NZ_CP040229.1\|WP_000101714.1\|2147326_2147935_-\|TIR-domain-containing-protein	gnl\|CDD\|378100	pfam08937, DUF1863, MTH538 TIR-like domain (DUF1863). This domain adopts the flavodoxin fold, that is, five parallel beta-strands and four helical segments. The structure is a three-layer sandwich with alpha-1 and alpha-4 on one side of the beta-sheet, and alpha-2 and alpha-3 on the other side. Probable role in signal transduction as a phosphorylation-independent conformational switch protein. This domain is similar to the TIR domain.	5.23558e-19
NZ_CP040229.1\|WP_000123402.1\|2136077_2137451_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP040229.1\|WP_099184063.1\|2150617_2150908_-\|DUF3387-domain-containing-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	2.17206e-37
NZ_CP040229.1\|WP_000003759.1\|2140572_2140893_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP040229.1\|WP_000019735.1\|2140894_2141875_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.75655e-109
NZ_CP040229.1\|WP_000160304.1\|2133732_2134443_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP040229.1\|WP_000070865.1\|2134563_2135007_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
NZ_CP040229.1\|WP_000370942.1\|2145329_2146187_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.61293e-60

>NZ_CP040229.1|WP_000495673.1|2142140_2143232_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPGDAYLKVIALLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLVGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILYVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP040229.1|WP_000019735.1|2140894_2141875_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVNTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP040229.1|WP_000003759.1|2140572_2140893_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP040229.1|WP_001024099.1|2139755_2140421_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NZ_CP040229.1|WP_001127960.1|2138383_2139322_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP040229.1|WP_000808818.1|2138122_2138353_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQTSASLKFSALLINVLPLCGTFVASN
>NZ_CP040229.1|WP_000123402.1|2136077_2137451_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP040229.1|WP_001123309.1|2135206_2135620_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQQPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP040229.1|WP_000070865.1|2134563_2135007_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP040229.1|WP_000160304.1|2133732_2134443_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP040229.1|WP_001802298.1|2143729_2143834_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP040229.1|WP_001792291.1|2144266_2144449_-|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>NZ_CP040229.1|WP_001792784.1|2144513_2144672_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP040229.1|WP_000220902.1|2145107_2145200_+|hypothetical-protein
MTYGSIVAILCALFAIFFIPYMEKKDKKKK
>NZ_CP040229.1|WP_000370942.1|2145329_2146187_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWLRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP040229.1|WP_000908191.1|2146254_2147037_-|ABC-transporter-ATP-binding-protein
MLIQLDQVGRMKQGKTILKNISWQINGGDKWILYGLNGAGKTTLLNILNAYEPATTGSVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP040229.1|WP_000101714.1|2147326_2147935_-|TIR-domain-containing-protein
MARKTFISYKYSEAKDLRDKIVESLGEDAKYYQGETSDSPDMSDRITEYIKKELKNKIYSTSVTIVVISPNMKESNWIDWEIEYSVKQMKRGDRTSSTNGVVGVVMKHNGDYSWLRNSVINSDGHTAIHTDNSYLYDIIVKNRFNQEPIEYTCDECKNIDALTGSFISLVEEDEFLGNPTKYIENAYEKSKKATNYNICRRK
>NZ_CP040229.1|WP_000876896.1|2147962_2148997_-|toll/interleukin-1-receptor-domain-containing-protein
MKYPIRQVAEVLPEKYTRYILLKEFQRLFPYQWNIIVERQQTYKEKAQHLYKVKKIKNRYNTKSAEEYFFSIPQVKYILSAGRMKKHKENYNASEIKIKKAALEKSRKNKNWKIEERLIKAKRYTQKVDPEYLNIYMKAYHKKDITTEEKLEILTELKKFDTENIVRFFRKLNDAEQNKMIRNLAFKYLQDYGHYVKLRKNFKGKKKVYQTERASLDTKKPEDLYNDLTNKNIQSQKVYDIFISHSTKDKKTVEDIIRVFNEQNKTCYCDWTMDQDYLKRKYVGEYTKQVLKARMEQSKMLVLLRTENSVQSDWVSFEIEYFENLKKPIYIVESLEELLEAFSD
>NZ_CP040229.1|WP_099184063.1|2150617_2150908_-|DUF3387-domain-containing-protein
MVMEENAFYDALASHDTAEHVLGDDTLKIIAHELTQSIKENMSIDWNLCESARAKMRVIVRRLLKKYGYPPEISKQAVETVIEQAELMSEQLAMEL
>NZ_CP040229.1|WP_001156920.1|2151032_2151437_-|hypothetical-protein
MQELEDYKEVQLIIIQMSSLPIGDGKRVFSYLEDGVTPRQYALATVSLFNGNEFKILEVERENCALSMLILSSTGLVNWNPLIDSLLLNLVNSSGTWVKESLEILERSNVIIQKAKHSKKEYAHRAKLLIHKML

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Crispr_ID: NZ_CP040229_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_9

2322416-2322501

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP040229_9

>merge|NZ_CP040229|9|2322416-2322501|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NZ_CP040229|9|9|2322416-2322501|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_138767021.1\|2319018_2319513_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP040229.1\|WP_138767022.1\|2319875_2320829_+\|hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240655
NZ_CP040229.1\|WP_000717395.1\|2314288_2315098_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP040229.1\|WP_000206106.1\|2318359_2318782_+\|DUF4870-domain-containing-protein	unknown	unknown	gnl\|CDD\|225833
NZ_CP040229.1\|WP_000606724.1\|2331773_2332103_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_072460394.1\|2322653_2323292_-\|autolysin	unknown	unknown	gnl\|CDD\|226656
NZ_CP040229.1\|WP_000921246.1\|2323451_2323685_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_001030125.1\|2330270_2330963_+\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP040229.1\|WP_000840813.1\|2323979_2324453_-\|DUF1641-domain-containing-protein	unknown	unknown	gnl\|CDD\|225283
NZ_CP040229.1\|WP_138767020.1\|2315534_2316935_-\|Na+/H+-antiporter-NhaC	unknown	unknown	gnl\|CDD\|188097
NZ_CP040229.1\|WP_001826090.1\|2322117_2322357_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000073196.1\|2332547_2333420_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP040229.1\|WP_000684154.1\|2320920_2322045_-\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|168661
NZ_CP040229.1\|WP_000684571.1\|2317029_2318112_-\|octopine-dehydrogenase	unknown	unknown	gnl\|CDD\|376763
NZ_CP040229.1\|WP_000426692.1\|2330987_2331725_-\|CPBP-family-intramembrane-metalloprotease-SdpB	unknown	unknown	gnl\|CDD\|376806
NZ_CP040229.1\|WP_016187165.1\|2328008_2328932_-\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|181811
NZ_CP040229.1\|WP_000130460.1\|2329088_2329886_-\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|223559
NZ_CP040229.1\|WP_138767019.1\|2311723_2313679_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP040229.1\|WP_001155267.1\|2324452_2327407_-\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|225918
NZ_CP040229.1\|WP_001826088.1\|2315166_2315361_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_138767021.1\|2319018_2319513_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.26375e-33
NZ_CP040229.1\|WP_138767022.1\|2319875_2320829_+\|hydroxyacid-dehydrogenase	gnl\|CDD\|240655	cd12178, 2-Hacid_dh_13, Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	9.77145e-180
NZ_CP040229.1\|WP_000717395.1\|2314288_2315098_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	9.81396e-31
NZ_CP040229.1\|WP_000206106.1\|2318359_2318782_+\|DUF4870-domain-containing-protein	gnl\|CDD\|225833	COG3296, COG3296, Uncharacterized protein conserved in bacteria [Function unknown].	7.90586e-53
NZ_CP040229.1\|WP_072460394.1\|2322653_2323292_-\|autolysin	gnl\|CDD\|226656	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].	8.08552e-103
NZ_CP040229.1\|WP_000073196.1\|2332547_2333420_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.12128e-80
NZ_CP040229.1\|WP_001155267.1\|2324452_2327407_-\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NZ_CP040229.1\|WP_138767020.1\|2315534_2316935_-\|Na+/H+-antiporter-NhaC	gnl\|CDD\|188097	TIGR00931, Uncharacterized_Na+/H+_antiporter_HI_1107, Na+/H+ antiporter NhaC. A single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of the NhaC family are found in both Gram-negative bacteria and Gram-positive bacteria. Intriguingly, archaeal homolog ArcD (just outside boundaries of family) has been identified as an arginine/ornithine antiporter. [Transport and binding proteins, Cations and iron carrying compounds].	1.77843e-114
NZ_CP040229.1\|WP_001030125.1\|2330270_2330963_+\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.1353e-57
NZ_CP040229.1\|WP_000840813.1\|2323979_2324453_-\|DUF1641-domain-containing-protein	gnl\|CDD\|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	1.05607e-29
NZ_CP040229.1\|WP_000684154.1\|2320920_2322045_-\|NAD(P)-binding-protein	gnl\|CDD\|168661	PRK06753, PRK06753, hypothetical protein; Provisional.	0
NZ_CP040229.1\|WP_000684571.1\|2317029_2318112_-\|octopine-dehydrogenase	gnl\|CDD\|376763	pfam02317, Octopine_DH, NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain. This group of enzymes act on the CH-NH substrate bond using NAD(+) or NADP(+) as an acceptor. The Pfam family consists mainly of octopine and nopaline dehydrogenases from Ti plasmids.	2.04121e-47
NZ_CP040229.1\|WP_000426692.1\|2330987_2331725_-\|CPBP-family-intramembrane-metalloprotease-SdpB	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.30887e-10
NZ_CP040229.1\|WP_016187165.1\|2328008_2328932_-\|putative-transcriptional-regulator	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	9.43081e-99
NZ_CP040229.1\|WP_000130460.1\|2329088_2329886_-\|inositol-monophosphatase	gnl\|CDD\|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	7.03254e-72
NZ_CP040229.1\|WP_138767019.1\|2311723_2313679_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.99387e-14

>NZ_CP040229.1|WP_001826090.1|2322117_2322357_-|hypothetical-protein
MKFSVLGPLTRVEKSLLQAHFHSVNYCQYNIIDPRTLIYVPSSHIIVTNVHYVNEYCCLNMHVIYNGADNTLKSLKMKR
>NZ_CP040229.1|WP_000684154.1|2320920_2322045_-|NAD(P)-binding-protein
MKIAIIGAGIGGLTAAALLQEQGHTIKVFEKNESVKEIGAGIGIGDNVLKKLGNHDLAKGIKNAGQILSTMTVLDDKDRPLTTVKLKSNTLNVTLPRQTLIDIIKSYVKDDAIFTNHEVTHIDNETDKVTIHFAEQESEAFDLCIGADGIHSKVRQSVNADSKVLYQGYTCFRGLIDDIDLKHPDCAKEYWGRKGRVGIVPLLNNQAYWFITINSKENNHKYSSFGKPHLQAYFNHYPNEVREILDKQSETGILLHNIYDLKPLKSFVYGRTILLGDAAHATTPNMGQGAGQAMEDAIVLVNCFNAYDFEKALQRYDKIRVKHTAKVIKRSRKIGKIAQYRSRLVVAVRNRIMKMMPNALAAGQTKFLYKSKEK
>NZ_CP040229.1|WP_138767022.1|2319875_2320829_+|hydroxyacid-dehydrogenase
MEKVYVAGAIPEVGLKLLQEHFEVEMYEGKGLVDKDTLIKGVKDATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNATADLTIGLVLAVARHIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLIDTEQFKMMKSTAYLINASRGPIVHEQALVQALKNNEIEGAALDVYEFEPDITDDLKSLNNVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN
>NZ_CP040229.1|WP_138767021.1|2319018_2319513_+|CHAP-domain-containing-protein
MKKLVTATTLTAGIGTALVGHAQHADAAENYTNYNNYNTTQTTTTTTTTTTTSSISHSGNLYTAGQCTWYVYDKVGGEIGSTWGNANNWAAAAQGAGFTVNHTPSKGAILQSSEGPFGHVAYVESVNSDGSVTISEMNYSGGPFSVSSRTISASEAGNYNYIHI
>NZ_CP040229.1|WP_000206106.1|2318359_2318782_+|DUF4870-domain-containing-protein
MTTEMNDVTNHQPNRKSNDENIMAMLIYLLSLFTSIIGPLIIWLLKKDESKLVDRAGKNYLNYTISYIIWSIVLVVITFIGVFLIATDIDFIIIIGFIITFIGILSIFAFSILSFVFTIIACVKYYNGQEYVIPLTIRFI
>NZ_CP040229.1|WP_000684571.1|2317029_2318112_-|octopine-dehydrogenase
MKIAIVGSGNGAVTAAVDMVSKGHDVKLYCRNQSISKFQNAIEKGGFDFNNEGEERFVKFTDISDDMEYVLKDAEIVQVIIPSSYIEYYADVMAEHVTDNQLIFFNMAAAMGSIRFMNVLEDRHIETKPQLAEANTLTYGTRVDFENAAVDLSLNVRRIFFSTYDRSCLNDCYDKVSSIYDHLVKEESLIKTNLENGNPEVHPGPTLLNVGRIDYAGEFALYKEGITKHTVRLLHAIELERLNLGRRLGFELSTAKESRIERGYLERDKEDEPLNRLFNTSPVFSQIPGPNHVESRYLTEDIAYGLVLWSSLGRVIDVPTPNIDAVIVIASTILERDFFEEGLTVESIGLDKLDLEKYLK
>NZ_CP040229.1|WP_138767020.1|2315534_2316935_-|Na+/H+-antiporter-NhaC
MMTRKPTFLESISTMIVMVIVVVTGFVFFDIPIQVLLIIASAYAAWIAKRVGLTWQDLEKGIAERLNTAMPAILIILAVGIIVGSWMFSGTVPALIYYGLDLLNPSYFLISAFFISAVTSVATGTAWGSASTAGIALISIGNQLSISPGMAAGAIIAGAVFGDKMSPLSDTTNLAALVTKVNIFKHIRSMMWTTIPASIIGLLVWFIAGFQFKGHSNDKQIQTLLSELAHIYQINIWVWVPLIVIIVCLLFKMATVPAMLISSFSAIIVGTFNHHFKMTDGFKAIFSGFNDSMIHQSHISSSVKSLLEQGGMMSMTQILVTIFCGYAFAGIVEKAGCLEVLLTTISKGIHSVGSLICITVICCIALVFAAGVASIVIIMVGVLMKDLFEKYQVSRSVLSKTLEDSSTMVLPLIPWGTSGIYYTNQLHVSVGEFFIWTVPCYLCAIIAIIYGFTGIGIKKSSNSRLT
>NZ_CP040229.1|WP_001826088.1|2315166_2315361_-|hypothetical-protein
MTKLIENLKASIFVSTLTKNLSMYSRFDAPKFGCVNGCMLFILYYRVNRIGENRSFEISTNPIF
>NZ_CP040229.1|WP_000717395.1|2314288_2315098_+|CHAP-domain-containing-protein
MKKIATATIATAGFATIAIASGNQAHASEQDNYGYNPNDPTSYSYTYTIDAQGNYHYTWKGNWHPSQLNQDNGYYSYYYYNGYNNYSYNNYNNGYSYNNYSRYNNYSNNNQSYNYNNYNSYNTNSYRTGGLGASYSTSSNNVQVTTTMAPSSNGRSISSGYTSGRNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAARAGYTVNNTPKAGAIMQTTQGAYGHVAYVESVNSNGSVRVSEMNYGYGPGVVTSRTISASQAAGYNFIH
>NZ_CP040229.1|WP_138767019.1|2311723_2313679_-|helix-turn-helix-domain-containing-protein
MTDNYSLHIFKSMKMSSVKEANLKIIYWLQGTGVVSINLQQYDVKRNDVTVIMLNDLYQIDGHDDSVCCVVEVSAKTFLKFMNANYMMRGKILTNEVASTLRILIKYLIYSKIKQQPYNANDKIINYMCVELMSLNTYDGSRHLVAEEVHDYLTNNHHKKINRKDVINQVSITNKALSDMFKATPYSNFIQYLNHIRLEHCLIDILTSKKPIEEIASSHGFNHYSRFIHLFKETYGDTPKLIRKRNSPTSHSINHSQLVEIDKNIIELFDDTNQSSSSMREIDIPFEPTKRSQMYQPKNIYIKRSNFYWMDYYTIKQIIQRLGVNPENLHIIVTIDTSNELSIEQITLLLQKIVNYNVNVVFRIKHEYKELLTSTERGKIEKLVATIFNMTFESNRCKIAFLINDLNTTAIQKLKRLIDNYIGVFELIYHLEPNELNTRYDKEIDHLIDYFILPLRQIEQVSIARSKIICDVDLINENNDLKEKITMSDINKVTELLTNYTKFRGLIMHMSIISEASKEINLTRLSIFIFIINILNQLRGIVIYQNDTMIVTKFKHEVQCVICLPAALLNENSDAIRLSCKGLQQFSHAKTKQIVLSIDKDNHTSENGVLVNDIMQQHSYWKANFIERNIYDHSLMVSSNSIVHLKYHLEI
>NZ_CP040229.1|WP_072460394.1|2322653_2323292_-|autolysin
MQQGKGIVQTKEEDGKFVEANNNEIAKAMTISHKDNDMKYMDITEKVPMSESEVNQLLKGKGILENRGKVFLEAQEKYEVNVIYLVSHALVETGNGKSELAKGIKDGKKRYYNFFGIGAFDSSAVRSGKSYAEKEQWTSPDKAILGGAKFIRNEYFENNQLNLYQMRWNPENPAQHQYASDIRWADKIAKLMDKSYKQFGIKKDDIRQTYYK
>NZ_CP040229.1|WP_000921246.1|2323451_2323685_-|hypothetical-protein
MLKTSAVISNTLLVIGLVCLFMMKLVLAITFFAVSLSISLVVFNMMFRDRTTMKVIVNASFLIVILAIVVAYFLLSK
>NZ_CP040229.1|WP_000840813.1|2323979_2324453_-|DUF1641-domain-containing-protein
MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKLIKVLDDAKILDALNGAVRGRQVIINKFAVELNKDIYTGLLSNMASMVFLLGELNVSDLSDFLNKVNKGLHVANQASPNAKTSVRSLFGVLKDDDMNRSLTYMLNMLKGMSRED
>NZ_CP040229.1|WP_001155267.1|2324452_2327407_-|formate-dehydrogenase-subunit-alpha
MQEHLVVTLDGKDYLVEPGTNLLEFIKSQDTFVPSICYNESMGPIQTCDTCTVEIDGKIERSCSTVIDRPMTVNTVNNDVKDAQKEALDRILEKHMLYCTVCDYNNGDCEIHNTMDAWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDIEVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMTDTEPGSLAAMIDLTKKAEPGYGPLFAISDSEAEMRKERIKKTKTVCTYCGVGCSFEVWTKDREILKVQPSHDSPANKIATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEALNVIADNFTSIKEKHGPDALSFISSSKATNEESYLMQKLARQVIGTNNVDNCSRYCQAPATKGLFRTVGHGGDSGSIEDLEKAAMSVLIGTNTAEAHPVIASRMKRAQKLFGQKIHVFDIRKHEMAERADRFYQPKPGTDLAWLSAVTKYIIDHDLHDKAFIEEWVEDFDEYYKSLETFTMAFAEEATGIPEAELIKFAEECAKAESVVICWAMGITQQDIGSDSSTAISNLLLVTGNYRRPGTGAYPLRGHNNVQGCSDMGSMPDKITGYQSIEADDIRAKFEKEYGVKLNPKAGKDNHEMVEGIHDGQIHSLYLYGEDTGIVDSNINFVQAAFEKLDFMVVQDEFLTFTATFADVVLPASPSLEKDGTFTNTERRIQRLYQALKPLGESKPDWKIFQAIANKLGFDWNYKHPSEIMDEIARLTPLYAGVSYERLEGFNSLQWPVHPDGTDEPILYLEGFNFDNGKAKLFPLSFDNYFKQDEVYDIHVNNGRLLEHFHEGNMTYQTPMLKYKVPRAFVEISPELAEDRGIHEGAEVKLISETGEAVLQVHVTDRVKGKEIYIPLNNDAMENGDLGAINLLTNSDVDQYTDTPSYKRTSCRLEVITKRGKSPLNPNNFRVNKKRHPQYSVQVQKKWERPDYVFPGNQVDK
>NZ_CP040229.1|WP_016187165.1|2328008_2328932_-|putative-transcriptional-regulator
MSLPKKIFLWVFGILVILAIVAVVYVAAKIFITGNKIHNPLDRNHSELRDKKVSLNDGDPFTIALFGVDSDADRKKKGGGERSDSIMILSINPKTKKTEIVSIPRDTRAEIVGRDTTEKIAHAYAYGGPNMAVKSLEKLMNVPIDHYATIDMDGLHNMIDSIGGVDVVSNDTFTVDGVRFTKGQQTHVNGDQALKFIRSRKEEGAGGDFGRQQRQQIVLEAMANKIASPSSITHFNSLMNEIQNNVKTDLTLGDLNTIRSNYKDANDTINKHQLSGQGGIQSDGLYYFIPSEQSKAESTKLLKDNLE
>NZ_CP040229.1|WP_000130460.1|2329088_2329886_-|inositol-monophosphatase
MTDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATHFQEHQLLAEEKSNEMITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGIKMEEPPSLKLEDAIISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNANGGYQKYR
>NZ_CP040229.1|WP_001030125.1|2330270_2330963_+|YafY-family-transcriptional-regulator
MNKAERQNLIITAIQQNKKMTALELAKYCNVSKRTILRDIDDLENQGVKIYAHYGKNGGYQIQQAQSKIALNLSETQLSALFLVLNESQSYSTLPYKSEINAIIKQCLSLPQTRLRKLLKRMDFYIKFDDTQHMTLPMLFSDILIYCTERNVMLVDHRVDDNIKAENVIFIGLLCKHGHWHAVIYDIAQDKTAELEIENIIDISYSFGKTIQTRDISIDNYHQFLNPIDS
>NZ_CP040229.1|WP_000426692.1|2330987_2331725_-|CPBP-family-intramembrane-metalloprotease-SdpB
MENEKKKYTFKDIAWRDLFIIPIIGVLSFALTIAAYIVPILFGYYEIDSNLIFVGTITQALAYTIGIGAFYLFHLKVMPSRLRAGFAYIKKYWLRLSITYIIALILIYTYEYMTQFLPKHLQYSETANELELNKMFEVPVFLPVAFLLIVIVGPIVEEIVFRHILIGELGKKFNFIAMSIVSVFLFAFIHVTDAKSPFEFGPYLILSIILVFTYIKSGRNLGSTIALHIANNFVSFVISVISIYA
>NZ_CP040229.1|WP_000606724.1|2331773_2332103_+|hypothetical-protein
MINETKYMRQQITNLIQIIDTIKYNTLMTDWNIQTHIYKFNQIVTNELNKFKGFETSYIINENQVFYYEIITLLNKRPLRQVDYGNKIQYLNFYHTELSNALFAIKFAH
>NZ_CP040229.1|WP_000073196.1|2332547_2333420_+|MurR/RpiR-family-transcriptional-regulator
MSNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASLLDISTSSVIRFSKKITDGGFHDLKINISKYVPKASSIYNVELMNNESTESLRTKLHTRTTRALNHANNELNDKTIDQICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQLVQETHIFATLLATHNSNDSVILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVAQASNIVLTYGKTDENEMHMGATTSLFAQMFTIDILYYRYVALNYHASLDYITQSKMALDNYRKHLSNINFKH

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Crispr_ID: NZ_CP040229_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_10

2439908-2440002

Orphan

Consensus_repeat	Method
TTCTTCAAATTTATTTGTTAGAAAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_10

>merge|NZ_CP040229|10|2439908-2440002|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAGGCTTATGCAGTTGACGTTTTACGTCCAACTGCGTTCCTTCGTCTTCTTCAAATTTATTTGTTAGAAAGGC

>NZ_CP040229|10|10|2439908-2440002|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAGGC	TTATGCAGTTGACGTTTTACGTCCAACTGCGTTCCTTCGTC
TTCTTCAAATTTATTTGTTAGAAAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_001012240.1\|2432341_2433592_+\|FemA/FemB-family-glycyltransferase-FmhA	unknown	unknown	gnl\|CDD\|367067
NZ_CP040229.1\|WP_000762708.1\|2437629_2437734_+\|putative-metal-homeostasis-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000916697.1\|2443737_2444685_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	unknown	unknown	gnl\|CDD\|369625
NZ_CP040229.1\|WP_001807892.1\|2440180_2440300_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000479573.1\|2434416_2435136_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP040229.1\|WP_138767028.1\|2440394_2441705_+\|immunoglobulin-binding-protein-sbi	unknown	unknown	gnl\|CDD\|288473
NZ_CP040229.1\|WP_001046647.1\|2447989_2448997_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_CP040229.1\|WP_000594523.1\|2442240_2443170_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	unknown	unknown	gnl\|CDD\|369625
NZ_CP040229.1\|WP_000286872.1\|2446193_2446886_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_CP040229.1\|WP_000615466.1\|2433688_2434420_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP040229.1\|WP_000825936.1\|2435116_2435896_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270429
NZ_CP040229.1\|WP_000019127.1\|2438900_2439767_-\|cation-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP040229.1\|WP_000819845.1\|2431724_2432087_-\|DUF4467-domain-containing-protein	unknown	unknown	gnl\|CDD\|291399
NZ_CP040229.1\|WP_001110056.1\|2448998_2450357_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_CP040229.1\|WP_001125208.1\|2437887_2438574_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518
NZ_CP040229.1\|WP_000162807.1\|2431106_2431706_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NZ_CP040229.1\|WP_000038955.1\|2436016_2437456_-\|multidrug-efflux-MFS-transporter-MdeA	unknown	unknown	gnl\|CDD\|129794
NZ_CP040229.1\|WP_001056917.1\|2444686_2445664_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NZ_CP040229.1\|WP_000200954.1\|2445715_2446183_-\|QueT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623
NZ_CP040229.1\|WP_000971556.1\|2446896_2448012_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_001012240.1\|2432341_2433592_+\|FemA/FemB-family-glycyltransferase-FmhA	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_CP040229.1\|WP_000200954.1\|2445715_2446183_-\|QueT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00118414
NZ_CP040229.1\|WP_000916697.1\|2443737_2444685_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.12563e-91
NZ_CP040229.1\|WP_000479573.1\|2434416_2435136_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	8.38308e-78
NZ_CP040229.1\|WP_001110056.1\|2448998_2450357_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NZ_CP040229.1\|WP_001046647.1\|2447989_2448997_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP040229.1\|WP_000594523.1\|2442240_2443170_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	3.62723e-97
NZ_CP040229.1\|WP_000286872.1\|2446193_2446886_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	8.32691e-130
NZ_CP040229.1\|WP_138767028.1\|2440394_2441705_+\|immunoglobulin-binding-protein-sbi	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	1.35538e-25
NZ_CP040229.1\|WP_000825936.1\|2435116_2435896_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.4238e-99
NZ_CP040229.1\|WP_000019127.1\|2438900_2439767_-\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.54055e-90
NZ_CP040229.1\|WP_000819845.1\|2431724_2432087_-\|DUF4467-domain-containing-protein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	4.12726e-31
NZ_CP040229.1\|WP_001125208.1\|2437887_2438574_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167
NZ_CP040229.1\|WP_000162807.1\|2431106_2431706_-\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	3.11803e-30
NZ_CP040229.1\|WP_000038955.1\|2436016_2437456_-\|multidrug-efflux-MFS-transporter-MdeA	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.17835e-92
NZ_CP040229.1\|WP_001056917.1\|2444686_2445664_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	2.43039e-128
NZ_CP040229.1\|WP_000971556.1\|2446896_2448012_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	7.0088e-136
NZ_CP040229.1\|WP_000615466.1\|2433688_2434420_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	8.01718e-147

>NZ_CP040229.1|WP_000019127.1|2438900_2439767_-|cation-transporter
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNAITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>NZ_CP040229.1|WP_001125208.1|2437887_2438574_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>NZ_CP040229.1|WP_000762708.1|2437629_2437734_+|putative-metal-homeostasis-protein
MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK
>NZ_CP040229.1|WP_000038955.1|2436016_2437456_-|multidrug-efflux-MFS-transporter-MdeA
MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGIVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIEMMNQIKIDTMLHGYHAGFLFALLITVISFFCSFMLQGKKKEVDSHQ
>NZ_CP040229.1|WP_000825936.1|2435116_2435896_-|transporter-substrate-binding-domain-containing-protein
MKRLLFVVIAFVFILAACGNNSSKDKEASKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKAEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSKSAFAFSKKVDDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>NZ_CP040229.1|WP_000479573.1|2434416_2435136_-|amino-acid-ABC-transporter-permease
MFLNLNSEQLHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKVLRSIARVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYRQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>NZ_CP040229.1|WP_000615466.1|2433688_2434420_-|amino-acid-ABC-transporter-ATP-binding-protein
MIQLNNIHKSFNDVEVIKGIDLSVGKGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVFVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKAEAREKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAREVSNNIVFIHEGEIGEQGAPEEIFNNPKTEELKRFLNVINEE
>NZ_CP040229.1|WP_001012240.1|2432341_2433592_+|FemA/FemB-family-glycyltransferase-FmhA
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEVLEESPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHINRYNFYGITGDFSESAEDYGVQQFKKGFNAHVEEYIGDFIKPIKPMLYKLQTYLKHKRR
>NZ_CP040229.1|WP_000819845.1|2431724_2432087_-|DUF4467-domain-containing-protein
MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQGFDSRRYYQQHDADYHEENMTN
>NZ_CP040229.1|WP_000162807.1|2431106_2431706_-|DsbA-family-protein
MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKCPYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQKDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAKGNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>NZ_CP040229.1|WP_001807892.1|2440180_2440300_-|hypothetical-protein
MLTNRLTSVNYVKKRLIQNIQRILSKEVLYEEMQYFANK
>NZ_CP040229.1|WP_138767028.1|2440394_2441705_+|immunoglobulin-binding-protein-sbi
MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAITKLQKNDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVETPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYTDKYFKYKGTIDKTVLSVFGNGYKSYIQPLKVEDQKNYVSKSYAQVRNYVTETLNTGKVLYAFYQNPKVVKAAITTAETASSIKNTLSNLLSFWK
>NZ_CP040229.1|WP_000594523.1|2442240_2443170_+|bi-component-gamma-hemolysin-HlgAB-subunit-A
MIKNKILTATLAVGLIAPLANPFTEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHEKGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>NZ_CP040229.1|WP_000916697.1|2443737_2444685_+|bi-component-gamma-hemolysin-HlgCB-subunit-C
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGNDVEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKNTNHIKSMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFKNRNYTVKYEVNWKTHEIKVKGQN
>NZ_CP040229.1|WP_001056917.1|2444686_2445664_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MNMNKLVKSSVATSMALLLLSNTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKAAGNINSGYERPNPKDYDFSKIYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NZ_CP040229.1|WP_000200954.1|2445715_2446183_-|QueT-transporter-family-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_CP040229.1|WP_000286872.1|2446193_2446886_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIDDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVIYETV
>NZ_CP040229.1|WP_000971556.1|2446896_2448012_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDQVDFESFMRKYSYHLSSSRLISGSSTVYEEIESMLADWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAEYPNQNIPKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGIDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHAEQDIDRLFEILHQED
>NZ_CP040229.1|WP_001046647.1|2447989_2448997_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYGTCENKENKNDVSRAN
>NZ_CP040229.1|WP_001110056.1|2448998_2450357_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGLSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMAAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRNCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC

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Crispr_ID: NZ_CP040229_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040229_11

2527510-2527620

Orphan

Consensus_repeat	Method
GGTACTTCTGGTGTCGGTGGCGTTGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040229_11

>merge|NZ_CP040229|11|2527510-2527620|CRISPRCasFinder
GGTACTTCTGGTGTCGGTGGCGTTGGTTCGCCTGGCTCACTCGGCACTTCTGGTGTCGGTGGTGTTGGTGTTTCCGGCTCACTCGGTACTTCTGGTGTCGGTGGTGTTGGT

>NZ_CP040229|11|11|2527510-2527620|CRISPRCasFinder
GGTACTTCTGGTGTCGGTGGCGTTGGT	TCGCCTGGCTCACTCGGCACTTCTGGTGTCGGTGGTGTTGGTGTTTCCGGCTCACTC
GGTACTTCTGGTGTCGGTGGTGTTGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040229.1\|WP_000274558.1\|2533813_2534491_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP040229.1\|WP_000282632.1\|2518509_2519703_+\|DNA-(cytosine-5-)-methyltransferase	unknown	unknown	gnl\|CDD\|273211
NZ_CP040229.1\|WP_138767031.1\|2517484_2518414_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|370247
NZ_CP040229.1\|WP_031774865.1\|2516468_2517242_-\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NZ_CP040229.1\|WP_001117057.1\|2536499_2536916_-\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|227213
NZ_CP040229.1\|WP_000581897.1\|2515592_2516357_-\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NZ_CP040229.1\|WP_000876647.1\|2532235_2533789_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP040229.1\|WP_000721337.1\|2522657_2523524_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP040229.1\|WP_000481425.1\|2530760_2532119_-\|gluconate-permease	unknown	unknown	gnl\|CDD\|129873
NZ_CP040229.1\|WP_001825629.1\|2539390_2539594_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000289136.1\|2535576_2536269_-\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NZ_CP040229.1\|WP_000678764.1\|2521813_2522080_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_072434834.1\|2530426_2530720_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_000586373.1\|2537054_2538878_-\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208
NZ_CP040229.1\|WP_000074000.1\|2534647_2535412_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP040229.1\|WP_000841387.1\|2523703_2526559_-\|fibronectin-binding-protein-FnbB	unknown	unknown	gnl\|CDD\|371043
NZ_CP040229.1\|WP_000660709.1\|2539789_2541067_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP040229.1\|WP_000217726.1\|2522223_2522532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040229.1\|WP_014937076.1\|2514559_2515345_-\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NZ_CP040229.1\|WP_138767032.1\|2519778_2521530_+\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092

Protein	Function_ID	Function_description	E-value
NZ_CP040229.1\|WP_000274558.1\|2533813_2534491_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	7.62004e-44
NZ_CP040229.1\|WP_000586373.1\|2537054_2538878_-\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	1.43413e-83
NZ_CP040229.1\|WP_138767031.1\|2517484_2518414_-\|restriction-endonuclease	gnl\|CDD\|370247	pfam09019, EcoRII-C, EcoRII C terminal. The C-terminal catalytic domain of the Restriction Endonuclease EcoRII has a restriction endonuclease-like fold with a central five-stranded mixed beta-sheet surrounded on both sides by alpha-helices. It cleaves DNA specifically at single 5' CCWGG sites.	8.10463e-11
NZ_CP040229.1\|WP_031774865.1\|2516468_2517242_-\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	3.80143e-129
NZ_CP040229.1\|WP_001117057.1\|2536499_2536916_-\|DUF2188-domain-containing-protein	gnl\|CDD\|227213	COG4876, COG4876, Uncharacterized protein conserved in bacteria [Function unknown].	1.54722e-61
NZ_CP040229.1\|WP_000581897.1\|2515592_2516357_-\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	2.21828e-125
NZ_CP040229.1\|WP_000876647.1\|2532235_2533789_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP040229.1\|WP_000721337.1\|2522657_2523524_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	5.5142e-177
NZ_CP040229.1\|WP_000481425.1\|2530760_2532119_-\|gluconate-permease	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	2.53789e-168
NZ_CP040229.1\|WP_000289136.1\|2535576_2536269_-\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	8.50652e-86
NZ_CP040229.1\|WP_000282632.1\|2518509_2519703_+\|DNA-(cytosine-5-)-methyltransferase	gnl\|CDD\|273211	TIGR00675, Modification_methylase, DNA-methyltransferase (dcm). All proteins in this family for which functions are known are DNA-cytosine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	1.26934e-125
NZ_CP040229.1\|WP_000074000.1\|2534647_2535412_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	3.96069e-33
NZ_CP040229.1\|WP_000841387.1\|2523703_2526559_-\|fibronectin-binding-protein-FnbB	gnl\|CDD\|371043	pfam10425, SdrG_C_C, C-terminus of bacterial fibrinogen-binding adhesin. This is the C-terminal half of a bacterial fibrinogen-binding adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin that allows attachment of the bacterium to host tissues via specific binding to the beta-chain of human fibrinogen (Fg). SdrG binds to its ligand with a dynamic "dock, lock, and latch" mechanism which represents a general mode of ligand-binding for structurally related cell wall-anchored proteins in most Gram-positive bacteria. The C-terminal part of SdrG(276-596) is integral to the folding of the immunoglobulin-like whole to create the docking grooves necessary for Fg binding. The domain is associated with families of Cna_B, pfam05738.	4.68514e-33
NZ_CP040229.1\|WP_000660709.1\|2539789_2541067_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.24287e-91
NZ_CP040229.1\|WP_014937076.1\|2514559_2515345_-\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	2.08363e-133
NZ_CP040229.1\|WP_138767032.1\|2519778_2521530_+\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0

>NZ_CP040229.1|WP_000841387.1|2523703_2526559_-|fibronectin-binding-protein-FnbB
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGNSATESKASETQTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPTTVQAPKAETSRVDLPSEKAADKGIVGTQVDTTQPSNVSEIKPRMKRSADVTAASEKEVVEEAKVTGTDVTSKVKVEEGSEIVGHNNKETNVVNPHNAERVTLKYKWKFEDGIKPGDYFDFTLSNNVETHGISPLRKVPDIKSKDGQVMAVGEVNEERKIRYTFKEYVQGKKDLKAELDLNLFIDPTTVTKRGNQNIEVTLGEKKISKQFDIKYLDGVKDNWGVTVNGRIHTLNKQEGRFSHFAYVKPNNQSLTSVTVTGQVTSGYKQNAKNPTVKVYKHIGSDELAESVYGDVLDETKFEDVTDKLSLTLTGNGGYTLDFSELDKTKNYVIKYEGDYNSSASDLNFQTKLSGYHNYYYSYYPVQLTWNNGVAFYSNNAQGDGKDKPKEPIIEHSTPIELEFKSEPPMEKHELTGTVEESDDSKPIDFEYHTAVEGAEGHAEGTIETEEDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTVEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIDEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNNGNQSFEEDTEEDKPKYEQGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPEVPSEPETPTPPTPEVPSEPGEPTPPTPEVPSEPETPVPPTPEVPSEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKQKQSKKSELPETGGEESTNKGILFGGLFSILGLALLRRNKKNHKA
>NZ_CP040229.1|WP_000721337.1|2522657_2523524_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKELGL
>NZ_CP040229.1|WP_000217726.1|2522223_2522532_+|hypothetical-protein
MTVNIVVSIVFCISMVVLSIYVAITKDFTLISYINQTTIADKHKNQIAYIFALCISLSAVFLMSAILCFEYDFIALAFLFLTIALLLIALFYVCFYKITKYP
>NZ_CP040229.1|WP_000678764.1|2521813_2522080_+|hypothetical-protein
MKGSKQILLIMGIISLIVLFIFTLFIMAQYAKHYEQKSDSSNAHTLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKD
>NZ_CP040229.1|WP_138767032.1|2519778_2521530_+|phospho-sugar-mutase
MFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLSRYLNAQTNNPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFEVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELVSRYIEDVGDPLQIDISFSKHNSSYIKPLPKSVAENYIKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVEYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSHPPQEIQGLKVKAIEDYLTSEVHQLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS
>NZ_CP040229.1|WP_000282632.1|2518509_2519703_+|DNA-(cytosine-5-)-methyltransferase
MYNNIITKNESDNSIPLNYGDFIKEKRNKLNMTQKELADSIGLPKFGDRTIRRWENYETSPSYLEYKTIMNFPDTPPYLNPNIYDYKMIDLFAGIGGTRLGFQLHGNVKCVFSSEWDKFSAKTYKANFGETPKGDITQIIADEIPTHDILVAGFPCQAFSQAGLKKGFNDTRGTLFFDIARILKAKRPKCFLLENVKNLRSHDKGKTFDIIMNTLLELDYDVSSSILRARDFGCPQNRERIYIVGFDKQQIKNAENFSFPEPLPIETSLGSILESNVNDKYTISDRLWYGHQRRKREHKAKGNGFGYSIFNETSPYTNTLSARYYKDGSEILIEQNKKNPRKLTPREAARLQGFPENYIIPVSDTQAYKQFGNSVSVPVVHAIASNIFQVLQQNKNN
>NZ_CP040229.1|WP_138767031.1|2517484_2518414_-|restriction-endonuclease
MTNLNNQLKEFKNTIKVERSKLLPSPFDMVYKNFEKLGYHKQNEQFFYDNASIIIDELRNQSWIEFKKIEKEFSKKLYSHLLDQDSENYKNMTVKEGIEKFTSKHTDEIYALQLSNTQSRRSRAGKEFESIIELVLMGANIEFVTQGSIGSGVFESSELAKLVDCVVLGAAEYNLNKRNTSLISAKTSLRERWQEVGDEMSRTKAKEMYLVTLDESISEKTLKLIEKNNIIIVTTKSVIDKNYLNSSNVISFEDMLNELHIQLLQWNNYGYPATELNNKKELYQTLIEKYDGNMFVRNYYENMLSNINV
>NZ_CP040229.1|WP_031774865.1|2516468_2517242_-|tandem-type-lipoprotein
MIHSRKLRLCLYLVLLAVFIGACGMKKEESSKDKQIKENFTKTLNLYPTKNLEDFYDKEGFRDQEFEKGDKGTWIVDSEMVIELKDKKMESRSMVLYINRNTRTTKGNFIVRELWEDSKGYAQSKDTKYPVKMEHNKIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYNSNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLIKGDGDLKGSSIAHKNLEFTFIENKEENIYFTDSINFKPTE
>NZ_CP040229.1|WP_000581897.1|2515592_2516357_-|tandem-type-lipoprotein
MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKEAFNKTLNVYPTKNLEDFYDKEGFRDQEFDKRDKGTWIINSGMNIQLKGGALKSRAMVLYINRNTRTAKGYFLISETTEDKKGYVHNKDKKYPVKMEHNQIIPTKPIRDDKLKKEIENFKFFVQYGDFKDYKDGDISYNPNVPSYSANYQLNNDDYNVQQLRKRYDISTKRAPELKLRGSGDLKGSSVGSKELEFNFIRNKEENVYFTDSINFKPTE
>NZ_CP040229.1|WP_014937076.1|2514559_2515345_-|tandem-type-lipoprotein
MIHSKKLKLCLCLIILSVFIGGCGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKEGFRDEEFEKGDKGTWIIHSKMIIETNGRNMESRGMVLYINRNTRTTKGNFVIREITEDSKGYSDSKDKKYPVKMENNRIVPMKPIHDEKLRKEIEDFKFFVQYGNFKDINDYKDGDISYNPNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLLKGDGDLKGSSVGSKNLEFTFVENKEENIYFTDSVQYTPSEDNNL
>NZ_CP040229.1|WP_072434834.1|2530426_2530720_-|hypothetical-protein
MALKHVYFYVENRLKYLESERYKKYIGYFSVMKGVSRHVFVRIVQAIIMKRLVYCFKLDNDEFNFKNKYKKYKPCVTRVFDDLNTIYRYISNNKIIN
>NZ_CP040229.1|WP_000481425.1|2530760_2532119_-|gluconate-permease
MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV
>NZ_CP040229.1|WP_000876647.1|2532235_2533789_-|gluconokinase
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDRYIIDYSMASATGMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVAVYQELVSIFINLSRSLTENYEQISDFQRQHMAENKTQ
>NZ_CP040229.1|WP_000274558.1|2533813_2534491_-|GntR-family-transcriptional-regulator
MYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>NZ_CP040229.1|WP_000074000.1|2534647_2535412_-|MerR-family-transcriptional-regulator
MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTEQQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLDKIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIISAILMKNKWPFLIALPFMISYGIGITIYYQRKVAYLCPNCQHIFSPSLWAVIKAKHTATTRRFECPNCHETHYCIEVPKTHMSTEQLEVPRTKNNN
>NZ_CP040229.1|WP_000289136.1|2535576_2536269_-|GTP-pyrophosphokinase-family-protein
MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE
>NZ_CP040229.1|WP_001117057.1|2536499_2536916_-|DUF2188-domain-containing-protein
MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEKTEVDSEYATTDNEEHIQEQSNQDKSYFDSESIVNQSGGVRQREPLMDGPHPKVVESFKDV
>NZ_CP040229.1|WP_000586373.1|2537054_2538878_-|FUSC-family-protein
MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVIICNLAFAICMILGTLTATTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPINLPIAPEEALYRGFAILVGGVLATMMVLITILLSKNKAEEQAIQNDFKLISKLLHAYNDKSAFSQVAKTAVDSFKASDKLLITSNSSSDKLSGRFQKLLLLHTSAQGIYSELLELNAKQIRPLPDELIEMMDHIITQRDDRNKNVRYWRKEVTVTEEFQNLFNHILKIDEMVHANEARIAYEAEMRKPLYSKRIYQNLTLDSIVFRNTLRYAAIMMIAIFIALMFDFEKAYWIPLSAHTVLLGTSTIHAIERGIARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALFTEALVGANYTIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAMGIVIAIIGLFVLGQRTASALLPYVMAEVVRKEATLFHYLFSENQYKDDVYQKNTAMNLSVKLNNMTQVYNAANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAKHLELNTELEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV
>NZ_CP040229.1|WP_001825629.1|2539390_2539594_-|hypothetical-protein
MKGNLEKYIRSLPLIGLIISIFLIILYFLIYRVEGNFCVIILYCLLPLFVNTSLYILYIIIFRYFKK
>NZ_CP040229.1|WP_000660709.1|2539789_2541067_-|MFS-transporter
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	891242-891272	0	1.0
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1952489-1952519	0	1.0
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	2011812-2011842	0	1.0
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	870450-870480	0	1.0
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	1600902-1600927	0	1.0
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	776324-776356	1	0.97
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	870508-870540	1	0.97
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	1332194-1332226	1	0.97
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	1952546-1952578	1	0.97
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	2277242-2277274	1	0.97
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	2322392-2322424	1	0.97
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	242265-242295	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	242323-242353	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	821111-821141	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	984208-984238	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	2277302-2277332	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	335977-336007	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	605668-605698	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	730041-730071	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1084506-1084536	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1084560-1084590	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1720633-1720663	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1811408-1811438	1	0.968
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	2322334-2322364	1	0.968
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	821175-821200	1	0.962
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	242205-242237	2	0.939
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	335862-335894	2	0.939
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	1010402-1010434	2	0.939
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	1600893-1600925	2	0.939
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	2097659-2097691	2	0.939
NZ_CP040229_1	1.1\|260376\|33\|NZ_CP040229\|CRISPRCasFinder	260376-260408	33	NZ_CP040229.1	2455335-2455367	2	0.939
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	785365-785395	2	0.935
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1336635-1336665	2	0.935
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	1382723-1382753	2	0.935
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	2288050-2288080	2	0.935
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	2722633-2722663	2	0.935
NZ_CP040229_3	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	NZ_CP040229.1	825219-825249	2	0.935
NZ_CP040229_4	4.1\|825543\|31\|NZ_CP040229\|CRISPRCasFinder	825543-825573	31	NZ_CP040229.1	770781-770811	2	0.935
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	825320-825345	2	0.923
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	870255-870280	2	0.923
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	1332306-1332331	2	0.923
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	2097657-2097682	2	0.923
NZ_CP040229_9	9.1\|2322446\|26\|NZ_CP040229\|CRISPRCasFinder	2322446-2322471	26	NZ_CP040229.1	2455344-2455369	2	0.923

1. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 891242-891272, mismatch: 0, identity: 1.0

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctgtgttggggccc	Protospacer
*******************************

2. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1952489-1952519, mismatch: 0, identity: 1.0

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctgtgttggggccc	Protospacer
*******************************

3. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 2011812-2011842, mismatch: 0, identity: 1.0

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctgtgttggggccc	Protospacer
*******************************

4. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 870450-870480, mismatch: 0, identity: 1.0

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctgtgttggggccc	Protospacer
*******************************

5. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 1600902-1600927, mismatch: 0, identity: 1.0

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
**************************

6. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 776324-776356, mismatch: 1, identity: 0.97

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagaagctgacgaaaagtcagc	Protospacer
********************.************

7. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 870508-870540, mismatch: 1, identity: 0.97

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagaagctgacgaaaagtcagc	Protospacer
********************.************

8. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 1332194-1332226, mismatch: 1, identity: 0.97

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagaagctgacgaaaagtcagc	Protospacer
********************.************

9. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 1952546-1952578, mismatch: 1, identity: 0.97

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagaagctgacgaaaagtcagc	Protospacer
********************.************

10. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 2277242-2277274, mismatch: 1, identity: 0.97

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagaagctgacgaaaagtcagc	Protospacer
********************.************

11. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 2322392-2322424, mismatch: 1, identity: 0.97

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagaagctgacgaaaagtcagc	Protospacer
********************.************

12. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 242265-242295, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctttgttggggccc	Protospacer
******************* ***********

13. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 242323-242353, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctttgttggggccc	Protospacer
******************* ***********

14. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 821111-821141, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctatgttggggccc	Protospacer
*******************.***********

15. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 984208-984238, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctttgttggggccc	Protospacer
******************* ***********

16. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 2277302-2277332, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctttgttggggccc	Protospacer
******************* ***********

17. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 335977-336007, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctatgttggggccc	Protospacer
*******************.***********

18. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 605668-605698, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctgtgttgggcccc	Protospacer
*************************** ***

19. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 730041-730071, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctttgttggggccc	Protospacer
******************* ***********

20. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1084506-1084536, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttctattcgaaattctctgtgttggggccc	Protospacer
***** *************************

21. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1084560-1084590, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttctattcgaaattctctgtgttggggccc	Protospacer
***** *************************

22. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1720633-1720663, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctatgttggggccc	Protospacer
*******************.***********

23. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1811408-1811438, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttgtcgaaattctctgtgttggggccc	Protospacer
****** ************************

24. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 2322334-2322364, mismatch: 1, identity: 0.968

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttctttttgaaattctctgtgttggggccc	Protospacer
********.**********************

25. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 821175-821200, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctgacgg	Protospacer
**********************.***

26. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 242205-242237, mismatch: 2, identity: 0.939

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacatagaagctggcggaaagtcagc	Protospacer
***********.***********.*********

27. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 335862-335894, mismatch: 2, identity: 0.939

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacaaagaagctgacgaaaagtcagc	Protospacer
*********** ********.************

28. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 1010402-1010434, mismatch: 2, identity: 0.939

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacaaagaagctgacgaaaagtcagc	Protospacer
*********** ********.************

29. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 1600893-1600925, mismatch: 2, identity: 0.939

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacatagaagctggcggaaagtcagc	Protospacer
***********.***********.*********

30. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 2097659-2097691, mismatch: 2, identity: 0.939

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacaaaagctggcggaaagtcagc	Protospacer
*************.*********.*********

31. spacer 1.1|260376|33|NZ_CP040229|CRISPRCasFinder matches to position: 2455335-2455367, mismatch: 2, identity: 0.939

gggccccaacacagaagctggcgaaaagtcagc	CRISPR spacer
gggccccaacacagtagctggcggaaagtcagc	Protospacer
************** ********.*********

32. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 785365-785395, mismatch: 2, identity: 0.935

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcatttcgaaattctctatgttggggccc	Protospacer
**** **************.***********

33. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1336635-1336665, mismatch: 2, identity: 0.935

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcggaattctctgtgttggagccc	Protospacer
**********.***************.****

34. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 1382723-1382753, mismatch: 2, identity: 0.935

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaaatctctgtgttgaggccc	Protospacer
************* ***********.*****

35. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 2288050-2288080, mismatch: 2, identity: 0.935

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttctttttgaaattctctatgttggggccc	Protospacer
********.**********.***********

36. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 2722633-2722663, mismatch: 2, identity: 0.935

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaattctctgtattgggggcc	Protospacer
*********************.****** **

37. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to position: 825219-825249, mismatch: 2, identity: 0.935

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttttcgaaatcctctgtgttggggacc	Protospacer
**************.************* **

38. spacer 4.1|825543|31|NZ_CP040229|CRISPRCasFinder matches to position: 770781-770811, mismatch: 2, identity: 0.935

aagaaccaatacataataaagcataagtgat	CRISPR spacer
aagaaccaatacataataaatcattagtgat	Protospacer
******************** *** ******

39. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 825320-825345, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagtagcaggcgg	Protospacer
**************** *** *****

40. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 870255-870280, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggtgg	Protospacer
*************.*********.**

41. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 1332306-1332331, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaaactggcgg	Protospacer
*************.****.*******

42. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 2097657-2097682, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacaaaagctggcgg	Protospacer
*************.*.**********

43. spacer 9.1|2322446|26|NZ_CP040229|CRISPRCasFinder matches to position: 2455344-2455369, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagtagctggcgg	Protospacer
*************.** *********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040229_7	7.1\|2086592\|34\|NZ_CP040229\|CRISPRCasFinder	2086592-2086625	34	NC_027332	Acinetobacter phage YMC13/03/R2096, complete genome	68639-68672	11	0.676
NZ_CP040229_7	7.1\|2086592\|34\|NZ_CP040229\|CRISPRCasFinder	2086592-2086625	34	KY000079	Acinetobacter phage AM24, complete genome	74925-74958	11	0.676

1. spacer 7.1|2086592|34|NZ_CP040229|CRISPRCasFinder matches to NC_027332 (Acinetobacter phage YMC13/03/R2096, complete genome) position: , mismatch: 11, identity: 0.676

tgctggtaccacgatgcgtcttgatgtagtgcta	CRISPR spacer
gatcaataccacgatgcgtcttgaagtggtagaa	Protospacer
 .....****************** **.**.  *

2. spacer 7.1|2086592|34|NZ_CP040229|CRISPRCasFinder matches to KY000079 (Acinetobacter phage AM24, complete genome) position: , mismatch: 11, identity: 0.676

tgctggtaccacgatgcgtcttgatgtagtgcta	CRISPR spacer
gatcaataccacgatgcgtcttgaagtggtagaa	Protospacer
 .....****************** **.**.  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

708232 : 716052

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|708232_709288_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|709287_709974_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037805.1\|709948_710422_-	DoxX family protein	NA	NA	NA	NA
WP_001093557.1\|710762_711203_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637685.1\|711483_712068_-	hypothetical protein	NA	NA	NA	NA
WP_001062968.1\|712166_712880_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|712883_713303_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|713304_713973_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604516.1\|714323_714917_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.1e-39	44.0
WP_001217786.1\|714900_716052_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_2

728022 : 742338

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663034.1\|728022_729081_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	1.5e-20	26.9
WP_001825709.1\|730082_730250_+	hypothetical protein	NA	NA	NA	NA
WP_000429003.1\|730518_731436_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.0
WP_014936998.1\|731526_731634_+	hypothetical protein	NA	NA	NA	NA
WP_000193750.1\|731705_733211_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_071938133.1\|733272_733479_-	hypothetical protein	NA	NA	NA	NA
WP_000930016.1\|733550_734051_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	2.7e-52	66.2
WP_138766939.1\|734070_734937_-	EamA family transporter	NA	NA	NA	NA
WP_078064764.1\|735321_735471_+	ribonucleoside-diphosphate reductase	NA	NA	NA	NA
WP_000692521.1\|735738_736137_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|736099_738205_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|738324_739296_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000876311.1\|739665_740637_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
WP_001245567.1\|740623_741580_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.6e-05	57.8
WP_000616865.1\|741576_742338_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.2e-17	30.1

DBSCAN-SWA_3

985703 : 994176

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001807816.1\|985703_986186_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010409.1\|986172_987297_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174055.1\|987300_988005_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	2.1e-47	42.1
WP_000848351.1\|988004_988268_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|988269_988941_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032750.1\|988933_991123_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-140	39.4
WP_000483707.1\|991101_992586_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	8.5e-46	31.7
WP_000030815.1\|992578_993607_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.9e-61	41.1
WP_000238668.1\|993609_994176_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.7e-29	40.1

DBSCAN-SWA_4

1228219 : 1300437

Staphylococcus_phage(90.67%)

protease,tail,transposase,holin,portal,head,integrase,tRNA,capsid

attL 1239881:1239896|attR 1248743:1248758

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000121214.1\|1228219_1229167_+\|transposase	IS30-like element ISSau1 family transposase	Q9MBM9	Staphylococcus_prophage	1.9e-184	99.7
WP_000655666.1\|1229205_1229499_+	thiamine-binding protein	NA	NA	NA	NA
WP_001001522.1\|1229632_1231177_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_000282384.1\|1231177_1231543_+	hypothetical protein	NA	NA	NA	NA
WP_000842283.1\|1231569_1232061_+	energy coupling factor transporter S component ThiW	NA	NA	NA	NA
WP_000073346.1\|1232363_1234982_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.9e-40	23.7
WP_000516257.1\|1234994_1237004_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	5.3e-59	29.5
WP_001072706.1\|1237009_1237552_+	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_138766965.1\|1238026_1238845_+	MIP family channel protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	3.1e-26	35.1
WP_000417370.1\|1238973_1240470_+	glycerol kinase GlpK	NA	NA	NA	NA
1239881:1239896	attL	NA	NA	NA	NA
WP_001218598.1\|1240627_1242301_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_000857185.1\|1242932_1243970_-\|integrase	site-specific integrase	Q38086	Staphylococcus_phage	4.5e-179	100.0
WP_001549185.1\|1244161_1244875_-	toxin MazF	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
WP_000694772.1\|1244953_1245136_-	hypothetical protein	A0A2I6PDF8	Staphylococcus_phage	6.9e-27	100.0
WP_031896415.1\|1245339_1245681_-	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	6.0e-56	99.1
WP_138766966.1\|1245686_1246619_-	ATP-dependent helicase	A0A2I6PEZ7	Staphylococcus_phage	7.4e-173	99.7
WP_001031454.1\|1246634_1247348_-	helix-turn-helix transcriptional regulator	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
WP_031929273.1\|1247310_1247484_+	hypothetical protein	NA	NA	NA	NA
WP_000854072.1\|1247480_1247744_+	helix-turn-helix transcriptional regulator	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
WP_001025404.1\|1247759_1247975_+	DUF2829 domain-containing protein	A0A0H3U4C7	Staphylococcus_phage	4.8e-35	100.0
WP_000128907.1\|1247963_1248293_-	hypothetical protein	M9NS98	Staphylococcus_phage	2.7e-53	100.0
WP_001148605.1\|1248343_1249096_+	oxidoreductase	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
1248743:1248758	attR	NA	NA	NA	NA
WP_001148862.1\|1249111_1249309_+	hypothetical protein	O80075	Staphylococcus_phage	3.5e-24	87.7
WP_000762521.1\|1249295_1249676_-	DUF2513 domain-containing protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
WP_001120201.1\|1249730_1250054_+	DUF771 domain-containing protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
WP_000048129.1\|1250050_1250212_+	DUF1270 family protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
WP_000165371.1\|1250306_1250609_+	DUF2482 family protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
WP_000291510.1\|1250613_1250874_+	DUF1108 family protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
WP_001205732.1\|1250882_1251146_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_031896414.1\|1251154_1253098_+	AAA family ATPase	S4V9K6	Staphylococcus_phage	0.0e+00	99.5
WP_000138475.1\|1253099_1254020_+	recombinase	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_071621397.1\|1254100_1254718_+	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	9.1e-87	100.0
WP_000934760.1\|1254718_1255189_+	single-stranded DNA-binding protein	A0EWX3	Staphylococcus_phage	7.4e-81	99.4
WP_031833239.1\|1255218_1256103_+	DnaD domain protein	A0A1W6JPN9	Staphylococcus_phage	1.7e-139	100.0
WP_000338527.1\|1256109_1256328_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	4.0e-37	98.6
WP_000401965.1\|1256336_1256792_+	RusA family crossover junction endodeoxyribonuclease	A0A1P8L6F2	Staphylococcus_phage	5.9e-83	99.3
WP_000101275.1\|1256804_1257173_+	hypothetical protein	I1W656	Staphylococcus_phage	6.3e-51	100.0
WP_000131384.1\|1257176_1257419_+	hypothetical protein	M1T302	Staphylococcus_phage	2.5e-40	97.5
WP_031875643.1\|1257432_1257687_+	DUF1024 family protein	A0A2I6PE79	Staphylococcus_phage	6.5e-39	98.8
WP_001066447.1\|1257836_1258373_+	hypothetical protein	A0A0H3U2Z8	Staphylococcus_phage	7.2e-96	100.0
WP_001282074.1\|1258409_1258655_+	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_000195803.1\|1258651_1258858_+	DUF1381 domain-containing protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
WP_000592207.1\|1258854_1259241_+	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
WP_000595265.1\|1259237_1259387_+	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000265043.1\|1259386_1259587_+	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
WP_000590122.1\|1259614_1260031_+	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000988336.1\|1260262_1260562_+	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000402904.1\|1260691_1261036_+	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000025274.1\|1262708_1263896_+\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000642728.1\|1263879_1264617_+\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_138766967.1\|1264640_1265786_+\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	6.2e-214	99.7
WP_138766968.1\|1265805_1266066_+	hypothetical protein	A0A0H3U504	Staphylococcus_phage	5.4e-41	98.8
WP_000150936.1\|1266078_1266363_+\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000755150.1\|1266346_1266709_+\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_138766969.1\|1266705_1267110_+	hypothetical protein	G4KNQ5	Staphylococcus_phage	4.8e-68	98.5
WP_000565498.1\|1267106_1267514_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000268740.1\|1267514_1268159_+\|tail	phage tail protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
WP_071621395.1\|1268200_1268425_+	hypothetical protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
WP_001096355.1\|1268474_1268825_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_061819789.1\|1269069_1273614_+\|tail	phage tail tape measure protein	A0A075M036	Staphylococcus_phage	0.0e+00	98.6
WP_000567408.1\|1273610_1275095_+\|tail	phage tail protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_138766970.1\|1275110_1278893_+	hypothetical protein	A0A068A201	Staphylococcus_phage	0.0e+00	99.0
WP_001000058.1\|1278885_1279038_+	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_001262621.1\|1279083_1279371_+	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
WP_000340977.1\|1279426_1279801_+	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_000750412.1\|1280173_1280947_+	staphylococcal enterotoxin type A	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
WP_011447039.1\|1281055_1281232_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_031762631.1\|1281284_1281392_-	hypothetical protein	NA	NA	NA	NA
WP_000611512.1\|1281443_1281698_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|1281709_1282465_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000920038.1\|1282655_1283147_+	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
WP_001793418.1\|1283593_1283749_-	hypothetical protein	NA	NA	NA	NA
WP_001791825.1\|1283675_1283930_+	hypothetical protein	Q4ZCK0	Staphylococcus_virus	8.0e-13	93.0
WP_001110820.1\|1283836_1284133_+	peptidoglycan hydrolase	A0A1P8L6B4	Staphylococcus_phage	1.6e-49	95.9
WP_000702263.1\|1284643_1284994_+	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_001791826.1\|1285046_1285307_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_001789576.1\|1285285_1285594_-	hypothetical protein	M9NTD8	Staphylococcus_phage	3.2e-40	100.0
WP_000669791.1\|1285617_1285797_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
WP_001807854.1\|1286704_1287640_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_000561357.1\|1287654_1287888_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_000448080.1\|1288109_1288586_-	glutathione peroxidase	Q70H87	Fowlpox_virus	1.6e-22	38.0
WP_000068615.1\|1288697_1289936_+	GTPase HflX	NA	NA	NA	NA
WP_000652039.1\|1289954_1291193_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000624945.1\|1291436_1291805_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_001126603.1\|1291823_1293164_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_001807853.1\|1293682_1293880_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	9.9e-11	50.0
WP_074347689.1\|1294566_1294794_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.9e-18	72.1
WP_001002341.1\|1295089_1295296_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	5.5e-12	55.2
WP_001788716.1\|1295996_1296107_+	hypothetical protein	NA	NA	NA	NA
WP_000006110.1\|1296499_1296685_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_000477489.1\|1297195_1297612_+	hypothetical protein	NA	NA	NA	NA
WP_000974166.1\|1298043_1298628_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	4.4e-30	42.6
WP_000585092.1\|1299276_1299528_+	hypothetical protein	NA	NA	NA	NA
WP_074347678.1\|1299597_1300437_+\|head	head morphogenesis protein	A0A1J0MFV1	Staphylococcus_phage	1.1e-29	50.7

DBSCAN-SWA_5

1572501 : 1580813

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1572501_1573287_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924214.1\|1573412_1574303_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062171.1\|1574312_1575659_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683941.1\|1575772_1576873_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
WP_000624563.1\|1576875_1577553_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1577683_1578790_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217255.1\|1579013_1580813_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_6

1650234 : 1659277

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1650234_1650753_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000595008.1\|1650774_1653048_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.1e-64	29.3
WP_000749801.1\|1653250_1655530_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_138766984.1\|1655804_1656065_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	6.3e-05	35.3
WP_001112045.1\|1656083_1657223_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019177.1\|1657245_1658271_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005766.1\|1658272_1659277_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_7

1782751 : 1830654

Staphylococcus_phage(91.89%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_138766987.1\|1782751_1789300_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.8e-294	94.9
WP_000836471.1\|1789623_1789935_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.3e-49	95.1
WP_001807819.1\|1789956_1792374_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.1
WP_001025063.1\|1792669_1793842_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.2e-216	99.7
WP_000526541.1\|1793951_1794905_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	6.4e-79	99.3
WP_000764426.1\|1794901_1795465_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	7.3e-99	95.7
WP_000757543.1\|1795583_1795985_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1796556_1797384_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1797386_1797506_-	hypothetical protein	NA	NA	NA	NA
WP_001834472.1\|1797517_1797709_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1797617_1798619_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008555.1\|1798746_1799205_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.1e-68	97.4
WP_001159034.1\|1799217_1800399_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.9e-226	99.7
WP_000493892.1\|1800409_1801042_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000384182.1\|1801048_1802080_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.1e-196	99.1
WP_001261673.1\|1802572_1804075_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	5.0e-30	98.6
WP_000221190.1\|1804717_1805032_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.3e-52	98.1
WP_000989103.1\|1805031_1806324_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	7.5e-216	94.7
WP_001032832.1\|1806410_1807265_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1807540_1807765_-	hypothetical protein	NA	NA	NA	NA
WP_000671058.1\|1807963_1808434_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	5.0e-69	84.6
WP_001153741.1\|1808546_1808990_+	competence protein ComK	NA	NA	NA	NA
WP_001030475.1\|1808976_1809420_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	6.4e-50	78.6
WP_001168915.1\|1809717_1810353_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000492903.1\|1810519_1811140_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001096494.1\|1811762_1812476_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091443.1\|1812734_1813037_+	hypothetical protein	NA	NA	NA	NA
WP_001200546.1\|1813291_1813657_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.9e-58	98.3
WP_000623484.1\|1813653_1814007_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.3e-18	82.1
WP_000453302.1\|1814256_1815090_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.7e-157	98.9
WP_000366160.1\|1815301_1816210_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.3e-137	99.3
WP_000933822.1\|1816334_1817528_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109913.1\|1817899_1819492_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.6
WP_138767045.1\|1819788_1820535_-	prolyl oligopeptidase family serine peptidase	A0A2H4PQM6	Staphylococcus_phage	2.3e-140	97.6
WP_000672013.1\|1820539_1821013_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1\|1821078_1821336_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778553.1\|1821332_1822334_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.3e-163	86.5
WP_000348381.1\|1822338_1823817_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.7e-277	95.5
WP_016187363.1\|1823975_1824431_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	8.3e-77	96.6
WP_001825423.1\|1824733_1825396_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.8e-49	87.7
WP_000070644.1\|1825476_1826472_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.3e-69	94.8
WP_000669036.1\|1826546_1827173_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	9.9e-81	84.1
WP_000627549.1\|1827213_1827558_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	5.1e-55	96.5
WP_000414230.1\|1827655_1828228_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.5e-24	93.1
WP_000864133.1\|1828425_1828983_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	1.1e-78	98.1
WP_000375476.1\|1829353_1829530_-	hypothetical protein	NA	NA	NA	NA
WP_000070813.1\|1829540_1829924_-	hypothetical protein	NA	NA	NA	NA
WP_000196442.1\|1830372_1830654_-\|transposase	IS3 family transposase	A0A0C5AJ30	Paenibacillus_phage	3.2e-23	63.4

DBSCAN-SWA_8

1869045 : 1942559

Staphylococcus_phage(76.47%)

tail,plate,holin,portal,head,tRNA,integrase,terminase,capsid

attL 1934074:1934092|attR 1946718:1946736

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181394.1\|1869045_1869516_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_001793998.1\|1869520_1870663_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_138766988.1\|1870798_1871527_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.9e-36	42.7
WP_000649908.1\|1871513_1872971_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_000063551.1\|1873227_1874289_-	PTS transporter subunit IIC	NA	NA	NA	NA
WP_000110011.1\|1883234_1883681_-	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
WP_000869465.1\|1883777_1884728_-	2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_000939521.1\|1884733_1885189_-	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_001011603.1\|1885269_1886559_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_001807907.1\|1886851_1887946_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_000597248.1\|1888136_1889873_-	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	1.3e-53	30.4
WP_000251253.1\|1890163_1890706_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000284749.1\|1891008_1892046_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000379101.1\|1892197_1893175_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_014937047.1\|1893278_1893509_+	hypothetical protein	NA	NA	NA	NA
WP_000886473.1\|1893435_1894272_-	membrane protein	NA	NA	NA	NA
WP_000535846.1\|1894280_1895798_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000435806.1\|1895812_1896127_-	YfhH family protein	NA	NA	NA	NA
WP_001124416.1\|1896104_1896923_-	recombination regulator RecX	NA	NA	NA	NA
WP_000830380.1\|1897183_1897993_-	monofunctional peptidoglycan glycosyltransferase SgtB	NA	NA	NA	NA
WP_000163283.1\|1898333_1898849_-	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_001005407.1\|1898978_1899140_-	hypothetical protein	NA	NA	NA	NA
WP_100250272.1\|1899486_1899567_+	hypothetical protein	NA	NA	NA	NA
WP_000382163.1\|1899892_1900093_-	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0
WP_000139423.1\|1900079_1900190_-	hypothetical protein	W5R8J7	Staphylococcus_phage	1.7e-12	100.0
WP_001788502.1\|1900260_1900413_-	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	3.1e-20	100.0
WP_138766989.1\|1900655_1902101_-	CHAP domain-containing protein	A0A0H4ITZ3	Staphylococcus_phage	6.9e-295	99.4
WP_138766990.1\|1902081_1902519_-\|holin	phage holin	A0A2H4PQP0	Staphylococcus_phage	1.2e-72	99.3
WP_000398874.1\|1902574_1902970_-	hypothetical protein	A1KX48	Staphylococcus_virus	2.7e-68	100.0
WP_138766991.1\|1902975_1904214_-\|plate	BppU family phage baseplate upper protein	A0A0F6N3G7	Staphylococcus_phage	2.9e-209	99.3
WP_138766992.1\|1904226_1906101_-	CHAP domain-containing protein	Q4ZBX1	Staphylococcus_virus	0.0e+00	99.8
WP_000466769.1\|1906237_1906537_-	DUF2951 domain-containing protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
WP_001790193.1\|1906577_1906751_-	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_000705921.1\|1906754_1907132_-	DUF2977 domain-containing protein	Q4ZBX4	Staphylococcus_virus	1.6e-54	100.0
WP_029052110.1\|1907131_1908955_-\|plate	phage baseplate upper protein	A0A0F6N3G2	Staphylococcus_phage	0.0e+00	99.8
WP_138766993.1\|1908954_1910853_-	hypothetical protein	Q4ZBX7	Staphylococcus_virus	0.0e+00	99.7
WP_001573307.1\|1910865_1912752_-	hypothetical protein	Q4ZBQ3	Staphylococcus_phage	0.0e+00	99.8
WP_138766994.1\|1912762_1913704_-\|tail	phage tail protein	Q4ZBQ4	Staphylococcus_phage	1.5e-181	99.7
WP_138766995.1\|1913718_1916862_-\|terminase	terminase	Q4ZBY3	Staphylococcus_virus	0.0e+00	99.9
WP_000880587.1\|1916865_1917150_-	hypothetical protein	A0A0N7E0V9	Staphylococcus_phage	8.8e-45	100.0
WP_000134337.1\|1917194_1917701_-	hypothetical protein	Q4ZBQ7	Staphylococcus_phage	2.7e-92	100.0
WP_000057582.1\|1917767_1918325_-\|tail	tail protein	Q4ZBQ8	Staphylococcus_phage	8.2e-103	100.0
WP_000270192.1\|1918325_1918751_-	DUF3168 domain-containing protein	Q4ZBQ9	Staphylococcus_phage	5.5e-75	100.0
WP_001151330.1\|1918763_1919177_-	HK97 gp10 family phage protein	A0A0N9BAY5	Staphylococcus_phage	1.1e-75	100.0
WP_000483041.1\|1919163_1919499_-\|head	phage head closure protein	A0A0E3TAH8	Staphylococcus_phage	8.8e-60	100.0
WP_000177351.1\|1919510_1919861_-\|head,tail	phage head-tail adapter protein	A0A0H3U2R5	Staphylococcus_phage	1.9e-60	100.0
WP_000235168.1\|1920021_1920936_-\|capsid	phage major capsid protein	A0A0H3U2U7	Staphylococcus_phage	1.2e-170	100.0
WP_001019221.1\|1920952_1921537_-	DUF4355 domain-containing protein	A0A2H4JDY6	uncultured_Caudovirales_phage	7.3e-78	100.0
WP_138766996.1\|1921632_1922583_-\|head	phage head morphogenesis protein	A0A0H3U2Z4	Staphylococcus_phage	1.4e-174	99.4
WP_138766997.1\|1922551_1923976_-\|portal	phage portal protein	A0A0E3T9I6	Staphylococcus_phage	2.4e-271	99.8
WP_001037578.1\|1923972_1925196_-\|terminase	PBSX family phage terminase large subunit	A0A0N9BAX9	Staphylococcus_phage	7.5e-242	100.0
WP_000594087.1\|1925188_1925683_-	hypothetical protein	A0A0N9BAX3	Staphylococcus_phage	2.2e-83	99.4
WP_025174416.1\|1925851_1926106_+	hypothetical protein	Q4ZB48	Staphylococcus_virus	1.1e-19	78.6
WP_000286968.1\|1926035_1926437_-	hypothetical protein	A0A2H4PQK5	Staphylococcus_phage	5.6e-69	100.0
WP_031902440.1\|1926437_1926611_-	transcriptional regulator	Q4ZA36	Staphylococcus_virus	5.4e-21	94.7
WP_001799187.1\|1926607_1927003_-	hypothetical protein	A7TWI1	Staphylococcus_phage	3.3e-66	100.0
WP_000608278.1\|1926986_1927223_-	hypothetical protein	Q4ZDP0	Staphylococcus_virus	2.8e-36	100.0
WP_001072794.1\|1927215_1927419_-	hypothetical protein	B2ZYX5	Staphylococcus_phage	8.8e-31	98.5
WP_000195769.1\|1927415_1927622_-	DUF1381 domain-containing protein	A0A1W6JPY0	Staphylococcus_phage	1.6e-19	97.1
WP_000120374.1\|1927618_1927864_-	hypothetical protein	A9CR89	Staphylococcus_phage	6.5e-28	100.0
WP_138766998.1\|1927900_1928410_-	dUTP pyrophosphatase	Q8SDV3	Staphylococcus_phage	6.2e-89	98.2
WP_000700108.1\|1928402_1928645_-	hypothetical protein	A0A2I6PF40	Staphylococcus_phage	3.7e-36	100.0
WP_001065101.1\|1928634_1928871_-	DUF1024 family protein	A0A0H3U313	Staphylococcus_phage	5.3e-35	100.0
WP_001557190.1\|1928863_1929235_-	hypothetical protein	A0A0F6N3K4	Staphylococcus_phage	3.6e-54	100.0
WP_001562543.1\|1929243_1929486_-	phage protein	A0A0F6N3E1	Staphylococcus_phage	6.6e-41	100.0
WP_000029376.1\|1929489_1929846_-	hypothetical protein	A0A0F6N3E3	Staphylococcus_phage	6.5e-61	100.0
WP_000101252.1\|1929973_1930279_-	hypothetical protein	A0A0F6N4H9	Staphylococcus_phage	1.7e-49	100.0
WP_000049785.1\|1930465_1930870_-	DUF1064 domain-containing protein	A7TWN5	Staphylococcus_phage	1.6e-71	99.3
WP_001123688.1\|1930880_1931102_-	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_138766999.1\|1931269_1932043_-	ATP-binding protein	Q4ZAS1	Staphylococcus_virus	8.6e-143	99.2
WP_000504988.1\|1932052_1932856_-	replication protein	A0A2H4JCF5	uncultured_Caudovirales_phage	1.1e-121	100.0
WP_050959248.1\|1932827_1933523_-	hypothetical protein	A0A2I6PDA6	Staphylococcus_phage	3.7e-129	100.0
WP_001099009.1\|1933534_1933978_-	single-stranded DNA-binding protein	A0A2I6PD99	Staphylococcus_phage	1.8e-76	100.0
WP_000840496.1\|1933974_1934625_-	single-stranded DNA-binding protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
1934074:1934092	attL	NA	NA	NA	NA
WP_001004336.1\|1934625_1935162_-	hypothetical protein	A0A0F6N4M6	Staphylococcus_phage	1.4e-80	100.0
WP_001108164.1\|1935174_1935507_-	DUF1108 family protein	A0A2I6PDT0	Staphylococcus_phage	2.9e-55	100.0
WP_000829610.1\|1935439_1935757_-	hypothetical protein	A0A2I6PEL3	Staphylococcus_phage	3.9e-33	100.0
WP_000048124.1\|1935849_1936011_-	DUF1270 family protein	C7F7L3	Staphylococcus_phage	1.9e-20	100.0
WP_000594789.1\|1936003_1936225_-	hypothetical protein	B2ZYU8	Staphylococcus_phage	8.7e-32	100.0
WP_000395455.1\|1936295_1936526_+	hypothetical protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
WP_001148606.1\|1936692_1937445_-	oxidoreductase	A0A1X9H0A0	Staphylococcus_phage	1.5e-139	99.2
WP_000933364.1\|1937446_1937632_-	helix-turn-helix transcriptional regulator	A0A0H4IP57	Staphylococcus_phage	1.7e-25	98.4
WP_138767000.1\|1938076_1938559_+	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	2.4e-82	99.4
WP_000438350.1\|1938659_1938839_-	hypothetical protein	A0A0H3U490	Staphylococcus_phage	4.9e-25	96.6
WP_001106623.1\|1938854_1939109_-	helix-turn-helix transcriptional regulator	B7T095	Staphylococcus_virus	3.1e-41	98.8
WP_000874710.1\|1939298_1939937_+	LexA family transcriptional regulator	A0A0E3TAG1	Staphylococcus_phage	8.8e-117	100.0
WP_000705238.1\|1940002_1940170_+	hypothetical protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
WP_000337827.1\|1941220_1941400_-	hypothetical protein	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
WP_001145722.1\|1941512_1942559_+\|integrase	site-specific integrase	Q4ZB10	Staphylococcus_virus	5.5e-201	100.0
1946718:1946736	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP040229.1|WP_000384171.1|1807540_1807765_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP040229.1|WP_000384171.1|1807540_1807765_-|hypothetical-protein

1807540_1807765_-

74 aa aa

LuxR_C_like

Identity	Hit_domain_coverage
0.42857142857142855	0.7368421052631579

1782751-1830654

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP040229_3	Orphan	3.1\|776384\|31\|NZ_CP040229\|CRISPRCasFinder	776384-776414	31	1811438-1811408	1

1. spacer 3.1|776384|31|NZ_CP040229|CRISPRCasFinder matches to NZ_CP040229 position: 1811438-1811408, mismatch: 1

tttcttttcgaaattctctgtgttggggccc	CRISPR spacer
tttcttgtcgaaattctctgtgttggggccc	Protospacer
****** ************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP040229

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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