CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040695	Nocardioides sp. S-1144 chromosome, complete genome	18 crisprs	DEDDh,cas3,csa3,cas4,WYL,RT,PD-DExK,DinG	1	12	1	0

1. NZ_CP040695

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040695_1

• CRISPR_ID: NZ_CP040695_1
• CRISPR_location: 23814-23926
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_1

Consensus_repeat	Method
CGTGCAATTGCCGCGACCTGGCCAGCTCTCG	CRISPRCasFinder

spacers of NZ_CP040695_1

>1.1|23845|51|NZ_CP040695|CRISPRCasFinder
GGCTGGGAACTGGCCATACGTCGGCAATTGCGCGCGATGAACACGGCGTCC

CRISPR arrays and Neighbor proteins around NZ_CP040695_1

CRISPR arrays

The CRISPR arrays of NZ_CP040695_1

>merge|NZ_CP040695|1|23814-23926|CRISPRCasFinder
CGTGCAATTGCCGCGACCTGGCCAGCTCTCGGGCTGGGAACTGGCCATACGTCGGCAATTGCGCGCGATGAACACGGCGTCCCGTGCAATTGCCGCGATCTGGCCAGCTCTCG

>NZ_CP040695|1|1|23814-23926|CRISPRCasFinder
CGTGCAATTGCCGCGACCTGGCCAGCTCTCG	GGCTGGGAACTGGCCATACGTCGGCAATTGCGCGCGATGAACACGGCGTCC
CGTGCAATTGCCGCGATCTGGCCAGCTCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138874730.1|28910_30320_-|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl|CDD|223843
NZ_CP040695.2|WP_138874725.1|22406_22967_-|cell-division-protein-CrgA	unknown	unknown	gnl|CDD|377706
NZ_CP040695.2|WP_137294567.1|18678_19698_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153252
NZ_CP040695.2|WP_138874724.1|20646_21168_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_CP040695.2|WP_138874732.1|33559_34627_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|212492
NZ_CP040695.2|WP_138877009.1|30322_31696_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NZ_CP040695.2|WP_137294564.1|21178_22138_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759
NZ_CP040695.2|WP_138877008.1|17491_17842_+|DUF3817-domain-containing-protein	unknown	unknown	gnl|CDD|378962
NZ_CP040695.2|WP_138874723.1|17848_18682_+|patatin-like-phospholipase-family-protein	unknown	unknown	gnl|CDD|224666
NZ_CP040695.2|WP_138877007.1|15798_16542_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293828
NZ_CP040695.2|WP_138874731.1|32212_32959_-|DUF3662-domain-containing-protein	unknown	unknown	gnl|CDD|378850
NZ_CP040695.2|WP_137294555.1|35237_35729_+|glutathione-peroxidase	unknown	unknown	gnl|CDD|238207
NZ_CP040695.2|WP_134765786.1|31749_32220_-|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|224630
NZ_CP040695.2|WP_138874729.1|27430_28891_-|penicillin-binding-protein-2	unknown	unknown	gnl|CDD|223839
NZ_CP040695.2|WP_137294607.1|34667_35225_+|nitroreductase	unknown	unknown	gnl|CDD|380315
NZ_CP040695.2|WP_138874727.1|24004_25825_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP040695.2|WP_138874722.1|16730_17471_+|SURF1-family-protein	unknown	unknown	gnl|CDD|119401
NZ_CP040695.2|WP_138874728.1|25821_27408_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP040695.2|WP_137294566.1|19716_20439_-|hypothetical-protein	unknown	unknown	gnl|CDD|235334
NZ_CP040695.2|WP_148240221.1|22965_23772_+|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|377575

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138874730.1|28910_30320_-|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl|CDD|223843	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning].	9.94285e-83
NZ_CP040695.2|WP_138874725.1|22406_22967_-|cell-division-protein-CrgA	gnl|CDD|377706	pfam06781, CrgA, Cell division protein CrgA. CrgA is a trans-membrane (TM) protein, first described in Streptomyces as being required for sporulation through the coordination of several aspects of reproductive growth. In Mtb (Mycobacterium tuberculosis ) CrgA is a central component of the divisome, and consists of 93 residues with two predicted TM helices (TM1: residues 29-51; and TM2: residues 66-88). CrgA facilitates the recruitment of the proteins essential for peptidoglycan synthesis to the divisome and also stabilizes the divisome. Reduced production of CrgA results in elongated cells and reduced growth rate, and loss of CrgA impairs peptidoglycan synthesis. CrgA has homologs in other actinomycetes.	1.30201e-12
NZ_CP040695.2|WP_137294567.1|18678_19698_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153252	cd07990, LPLAT_LCLAT1-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.	5.84507e-14
NZ_CP040695.2|WP_138874724.1|20646_21168_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	4.25682e-65
NZ_CP040695.2|WP_138874732.1|33559_34627_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.07533e-45
NZ_CP040695.2|WP_138877009.1|30322_31696_-|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.4162e-63
NZ_CP040695.2|WP_137294564.1|21178_22138_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	3.20592e-36
NZ_CP040695.2|WP_138877008.1|17491_17842_+|DUF3817-domain-containing-protein	gnl|CDD|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	3.36154e-23
NZ_CP040695.2|WP_138874723.1|17848_18682_+|patatin-like-phospholipase-family-protein	gnl|CDD|224666	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only].	1.12903e-41
NZ_CP040695.2|WP_138877007.1|15798_16542_-|MBL-fold-metallo-hydrolase	gnl|CDD|293828	cd07742, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.49547e-90
NZ_CP040695.2|WP_138874731.1|32212_32959_-|DUF3662-domain-containing-protein	gnl|CDD|378850	pfam12401, DUF3662, Protein of unknown function (DUF2662). This domain family is found in bacteria, and is approximately 120 amino acids in length. The family is found in association with pfam00498.	6.83768e-52
NZ_CP040695.2|WP_137294555.1|35237_35729_+|glutathione-peroxidase	gnl|CDD|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	1.20156e-102
NZ_CP040695.2|WP_134765786.1|31749_32220_-|FHA-domain-containing-protein	gnl|CDD|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	9.77734e-20
NZ_CP040695.2|WP_138874729.1|27430_28891_-|penicillin-binding-protein-2	gnl|CDD|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	4.34229e-97
NZ_CP040695.2|WP_137294607.1|34667_35225_+|nitroreductase	gnl|CDD|380315	cd02138, TdsD-like, nitroreductase similar to Burkholderia pseudomallei TdsD. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to Burkholderia pseudomallei TdsD, may be involved in the processing of organosulfur compounds. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	1.44017e-59
NZ_CP040695.2|WP_138874727.1|24004_25825_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.01954e-119
NZ_CP040695.2|WP_138874722.1|16730_17471_+|SURF1-family-protein	gnl|CDD|119401	cd06662, SURF1, SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring complex of the respiratory chain, is an assemblage of nuclear and mitochondrially-encoded subunits. Its assembly is mediated by nuclear encoded assembly factors, one of which is Surf1/Shy1. Mutations in human Surf1 are a major cause of Leigh syndrome, a severe neurodegenerative disorder.	1.89748e-30
NZ_CP040695.2|WP_138874728.1|25821_27408_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.84299e-117
NZ_CP040695.2|WP_137294566.1|19716_20439_-|hypothetical-protein	gnl|CDD|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.00284543
NZ_CP040695.2|WP_148240221.1|22965_23772_+|DUF881-domain-containing-protein	gnl|CDD|377575	pfam05949, DUF881, Bacterial protein of unknown function (DUF881). This family consists of a series of hypothetical bacterial proteins. One of the family members YlxW from Bacillus subtilis is thought to be involved in cell division and sporulation.	3.42242e-46

Protein sequences

>NZ_CP040695.2|WP_148240221.1|22965_23772_+|DUF881-domain-containing-protein
MDPAHPVDPEVGTEVDGATPAGRSRGPWRIGTPVVVLLSGVLFVASATTSGGTDLRPGRYTDLASLTQSESESYEALQAEAASLRTEVEALTNDIDDVRVRREHRVAEELKGPAGLEAVSGEGLRIVLSDAPDDAFEDALREPDPEARLQRLVVHQQDIQAVVNALWAGGARAVTIQGQRVVTTTGIRCTGSTVQLQGVPYPEPYEIEAVGDPQTLQAAIDADQDVTDFRVDAASPDIGIGWELDQEPEVDAPAYEGLITMDSARPQD
>NZ_CP040695.2|WP_138874725.1|22406_22967_-|cell-division-protein-CrgA
MPTKVTRDRDAPWRARPRPQHPSDRNRPVAKLKAKQQTFDPDRGPVVGPRFLVAIALVVLGIAWIAFYYIGVRAPDGLNSEGAPNSATGPGFMQDLDQWNYLIGFGLFFLGLVVAAHPSTPLGRGRGVVVGMLGCFLLGLAWICVFYAIANQADPSLPIFNDLGQKNLGVGIAFMAVGFTFATRWE
>NZ_CP040695.2|WP_137294564.1|21178_22138_+|rhomboid-family-intramembrane-serine-protease
MSTSGPAGPPAPGVPVCYRHAGREAHIRCQRCDRPICPDCMRDAAVGFQCPTCISEGARSTRQGQGAYGGARSANPALTSMVLIGLNAAVWLAIVVTGWSQSPLLGRLAISARGICESVADPASYWRGVESAASCAMVGNGDGSWVPGVADGAYWQLVTSMFTHEQIWHIGANMLSLYVLGPQLEAALGRVRFLAVYLLSGLSGSVAVYWLSGTEGYTLGASTAIFGLFGAFAVIVHKVGGDLRSIGGLLLVNVVITFLPGLNISWQGHLGGLVGGVLVTAALVHAPRGPRRAVVQWCLLFAFTALLALAVIARSAALA
>NZ_CP040695.2|WP_138874724.1|20646_21168_+|peptidylprolyl-isomerase
MADQQAILKTNRGDITIDLFPNHAPETVANFTGLATGEKAYSTPDGRTGKFYDGLGFHRVISGFMIQGGCPLGTGTGGPGYTFKDEIHPELVFDKPYLLAMANAGPGTNGSQFFITVGATPWLNRKHTIFGEVADQASRDVVDAIGATPTAAGDRPVEPVVIESVEIVGGSEK
>NZ_CP040695.2|WP_137294566.1|19716_20439_-|hypothetical-protein
MGLRKKKSLVDQARTQASDYVDALKPHVESALEQAKDFVQDTAIPAISDARDKAGPALADARDKAAPVLADARAKAAPIVAGGAALAVEKASEVREKAAPLVATGASVAAARATQARELADSQVARIKGEEPKKKGKLKKFVLVALIAGGIAFVAKKLQGGKDDNWQSSYKPTPAPAPKPAAKPAAAPVTPATTTIDDPAGAAPDEAIADAVEAPHPVTTPDEPAEVVDIDPDAKPNTPD
>NZ_CP040695.2|WP_137294567.1|18678_19698_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MRHGFRRLVLAPAVVVLAVLTWVTLPVWLLVAAALSPVLPGRWRALRLLWLLVLYLTTEALVLVVLLGWWLASGLGRRVRTPYWEGVHYDLVQGVMWVFFREARRVLKLSITTDGPAPDAHPGVPILVACRHAGPGDSFTLIHALMHWYQREPRVVLKDTLAWDPAIDVLLNRIPARFIAPNPGPDADLASLVHALASGLDENDAFVIFPEGGNFTEERRDRAIARLRRLGLERMAQRAEQMTTVLAPRPGGLIAALDAAPDADVVLVAHTGLDHLLTVGDLWRALPMDKQIVMRWWQVPREEIPQDREARIEWLFDWWERIDDWIKQNRPEDRGPRGG
>NZ_CP040695.2|WP_138874723.1|17848_18682_+|patatin-like-phospholipase-family-protein
MSTAFVLGGGGVLGAVEVGMVQALLEHGVVPDLVLGTSIGAMNGALVAREPELAVVDRLLDLWRSAAASGRDVLGDTALRTVRRAVTSGTHLYSAEPLARRLADELGDVRFEELPVRFQVCAASIERAAEHWFTSGPVVPAVIASAAVPGLLPPAEVDGEHYLDGGIVNSVPLGRAVALGATRVFVLQVGRFDRPLEAPRRPWEVARVAFEIARRHRFVRELAELPDGVACHVLPARGTSGKDDTLRASRDFGSVERRIEQTYQACSAYLDELDGAP
>NZ_CP040695.2|WP_138877008.1|17491_17842_+|DUF3817-domain-containing-protein
MSRALLAYRVMATIVGVLLVVLILVGVPLKYLLEDGTGAQELGDWITGYLGVAHGWLYMIFLFAAFLLSRRADWDIPYTAVTLLCGTVPVLSFWAEHRATARVRREHGADAPATTS
>NZ_CP040695.2|WP_138874722.1|16730_17471_+|SURF1-family-protein
MRELLTPRMLGAHLLGLVCVLVAGGLGVWQYEAWQQHRENERVDLTQGEPVALADVLGPDDGFPADRIGQPVEIDGTWLPDATVFVGDRRHEGVDGYWVVTPITSGAVDQPAVPVVRGWVEDPADAPAPPTGAGEVTGWLQPPEGTGAADEDPTDDVFPQLRIADLVQRVDGDLYGAYAVAEGGVDGLPAGDLEELPEPSSTTALKNILYAIEWWVFGAFAGFIWWRFVRESRAPAVADHPVPSST
>NZ_CP040695.2|WP_138877007.1|15798_16542_-|MBL-fold-metallo-hydrolase
MVTHVLLVERAGGLLLVDTGFGTADVASPQRLGRAFKALMRPQLRDDETALAQVTALGHAADDVTDIVLTHMDLDHVGGVGDFPRARVHVYEAELAAARDPHGMEHGRYLPAQWQDADFVTHRTRGPGGGSGTGVDWFGFESVTVLGDDVLMVPLAGHSRGHALVAVRDGDGWLAHAGDAYFHRGDLAAPTSGPRTLRVVQRLMAQDDELRRANRDRLGELVRAGHDGLRVFSAHDPVELAAFATTG
>NZ_CP040695.2|WP_138874727.1|24004_25825_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MNDPGPTVVGGRYELGEMLGRGGMAEVRKGTDSRLGRIVAVKRLRTDLASDATFQARFRREAQSSASLNHPSIVAVYDTGEEPATDGSGVAQPYIVMEFVAGRTLRDILREGRKILPERALEITSGVLSALDYSHRAGIIHRDIKPGNVMLTPSGDIKVMDFGIARAMSDAANSMTQTAAVVGTAQYLSPEQARGESVDSRSDVYSAGCLLYELLTGRPPFVGDSPVAVAYQHVREQPSPPSDHDTELPPAVDAIVLKALTKRLEDRYQSAGAMRNDIERYLAGRPVEATVPPPPPAPEPAPVAAVAAPAPTPPRRPEPTPLPLAQEPGPPRTGLWVLLGLLVVALLVAGWFLVKDELFPEPPERTAVPGVIGMTEDQARQTIGNAGLTVDPEVVYENSDTVPAEEVVEQSPSKDDYVAPGSPITLTVSIGKEEVAVPSVVTLSLKAAKAELRDQGFTKVRQEEIESDRPKGEVLTQNPAAGTMVEKGTAITVEYSAGPEEVPFVIGKTEREATRLIEDAGFIVDVRPDTTSTEVKGTVTDQAQEAGQPLPQDSVVVIFVSVYVEPTTTSPPPTTDPVPTTDPVPTDPLPTEPPPSRGPAPSSDDD
>NZ_CP040695.2|WP_138874728.1|25821_27408_-|protein-kinase
MSELTDNFADDAGRFRLESRIATGGMGEVWRATDTVLGRQVAVKLLKTEYADDPTFRARFATEAQHAAALHHPGIASVFDVGERAATDGSGTPRPFLVMELVEGQPLSALIGSASGGRDLDPQAVRDLLSQVGDALGAAHRAGIIHRDVKPANLLVTPEGKVKVTDFGIARAADGVGITRTGAVMGTPQYLSPEQAEGRPATSASDVYALGVVAFECLAGHRPFEADSPVATALAHLRNPIPDLPASVPADLAAVVRRALSKKPEERYADGTAFAAALRDPAAADPATRVTTRTPVDPVPVVPLPPVGDTSATQVLGAAPAYDPTPTPPPAGPVTGTTDTAGATGPGRRNPWPVVAAVALIVALAIVLTLLLTGGDDDGDETSTDVTTTPSRTRTQSQSATTSGPETIELNASDYVGRQVEDVEDALGDLGLQVRRDEQDNDDPARDGEVTGLNPTGAVTEGDTITVTFLGVAPEETSEPPSEPPTTEPTTEPTTEPTTEPTTEPTSDPTETETETTETQPTEGETSP
>NZ_CP040695.2|WP_138874729.1|27430_28891_-|penicillin-binding-protein-2
MNKPIRSVSIFCLLLFVALMLNVTYLQFWQADSLNDRAENRRVKEAAYSSERGAILVGRTPIAESKPVDDEFNYLRTYPAKGLYAPVTGYFSFGSSSGIESSQNEVLSGDDPRLFIGSLVDLLSNKAPKGGNVQLTLDPDAQQAAYDGLAALGDDVEGSVVALQPSTGKILAMVSLPTFDPNRLASHDFATRDALYARLLEDDQDPLLNRAIQTRLFPGSVFKLVTAAAALESDKYDGPDAMVPGGSTFQLPQTSGEGGLIDNEGRYCGSGEITLRLAMEQSCNTTFAQLAIEVGAEGMLRQAEQFGFNSSYLEDLGGQVRSSFPDELTPPEVGQVGFGQFEVQATPLQMAMVAAAIANDGVVMRPYVVDEVQSADYDAQTTDPEELSRAISEETAETLREVMVSTVDDGTASPAAISGVSVGGKTGTAQRGVPGQPPYGWFVSFAPQDDADVAVAVMIQEAPGREIAGGALGGPIAKAVMEAIIR
>NZ_CP040695.2|WP_138874730.1|28910_30320_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MATTPGTGALMGFVHRRRRGAELFLLVLALAVGVGGYGAVGLGVDGEVPANLVGYGGWLAGLMVAAHVAVRLVAPYADPVLLPVVAALNGLGLAVIHRLDLAEDDSFAPQQLTWMTLGVILFVLTLLVLRDHRVLARFTYTAGLLAIVLLVLPMAPVIGKQVNGARIWINLGPFNFQPGEVAKVLLVVAFAGYLVLHRDALALAGRRVLFVDLPRGRDLGPILVMWLISLGILVFQRDLGSSLLFFGLFLLMLYVATERPGWVVVGALLFSGGAVAGYRLFGHVRVRVDTWLHPFEYYDGAAGENSYQLVEGLFGFSWGGLIGKGLGEGDPGRVPEASSDFIMAAIGEELGLTGVLAVLLLYGIVVERALRTALICRDNFGKLMATGLAGVFALQLFVVIGGVTRLIPLTGLTTSFLSYGGSSLVMSWVIIALLLRISDQARRPVPELTPEAESSPDDESTQVIKLSKT
>NZ_CP040695.2|WP_138877009.1|30322_31696_-|serine/threonine-protein-phosphatase
MPDQPADDATVVAPPARAALALHYSAISDVGRIRKDNQDSGYAGPWLLSVCDGVGGAARGDIASSTAISELRNLDAAPRPPGDGHPGDPDVLDRVTDALHEAHAQIGRLVDADPAINGTSTTATVALFDGRRLGIGHVGDSRAYLFRDNEISQLTTDHTFVQSLIDEGRITEAEARVHPHRNLILKALDGIHEAEPDLFVLELVAGDRLLLCSDGASGVLDDGRLADVLSMGTPDFAAVELVRASLEAGSSDNVTCIVADVVDAETAAADPAFAELEPLLVGAAAELKRKLPRGLFRGHRSGDTGELEPIDAEIPGDVPFAIPSDPLLPPDPEAARYAPIPPPRHTWLRRVMLLVIVVGLLWIGAAAAWSYVQQQYYIGEEDGVVVIHHGLNASLPGLELSDVVVVTTLAVDDLEEFDRESVRDGIPVDDLAEARERVEELAAKRTTSSAADGGGAS
>NZ_CP040695.2|WP_134765786.1|31749_32220_-|FHA-domain-containing-protein
MSELTFFLIRIAYLAILWIFVLAAISVIRSDMFGARVPEAVRTAPGPAPAKQKKPPKRRGSPTHVAVTQGSNTGATAGLDRAPILIGRGTDAAIRLDDDYVSTRHARIAASGDQWFVEDLGSTNGTYIGSVRITQPTTITLGTQVRIGKTILELRK
>NZ_CP040695.2|WP_138874731.1|32212_32959_-|DUF3662-domain-containing-protein
MGGLQRFEQKLESMISGAFARTFRSAVQPVEIAAALERELDQNAQILSRDRRLVPNDFHVELSDTDLSRLAPYDSTLARELSDQLQKHADGQGYVFPGPIRIDFETAEDLTTGRFRIRSEAQAKVVGTATHTQVRQALAVLEVNGTRHPLHPPGLVVGRGTDADLRINDPGISRRHLEFMVTAGRGEELPLIEVHDLGSTNGISVDGRKVPRAALHDGSQVKVGTTTMTVRIVTETHDSPREPGAADV
>NZ_CP040695.2|WP_138874732.1|33559_34627_+|SDR-family-NAD(P)-dependent-oxidoreductase
MSARAKSRLTSTLDTVLDRSLVLGYSRVGPALRRRWWPADPEPGCLAGQRVVVTGATSGIGEAMVTSFARLGATVHVLGRNPDKVRRVVAEVREALPGADLVEEVCDVGDLDVVRAWCADLTDRLGAGGALRGIVHNAGAMVAERTETAQGHELALAVHVLGPHLMTERLLPLLGADAGGPGGPGGPGSVVWMSSGGMYSAGLRSTPDEIEFRPVEGEQEYSGVRGYARTKRMQVELADAWNDRPDVRSGVRPGGGAGAGVRVESCHPGWAATPGVTDSLPGFDTVMGPLLRDAASGADTAVWLVATRPASAGTHHFWHDRRPRPTTYPVQRRPDPVARRAFLDHVAAATGTVWP
>NZ_CP040695.2|WP_137294607.1|34667_35225_+|nitroreductase
MPGAEDLAEPLRSRWSPSIFDADHVLAEADVVRLLEAARWAPSTGNSQPWRFVVAPRGSAAHAAFVPHLSRGNAGWVPAASLVLVAGCEVVDVKDPDYARYDLGQAAAHVTLQARAMGLHAHQLAGFDKDGAAAALGVPDHVRLMSAIAIGVRGDPALVAERDREREQRVRRRLPLAEIVWWDRA
>NZ_CP040695.2|WP_137294555.1|35237_35729_+|glutathione-peroxidase
MTSLKDFSATTLDGQPVDLSAYAGQVVLVVNTASECGFTGQYEGLQQLHERYADQGLVVLGFPCDQFGGQEPGDEAQIGAFCQKNYGVTFPMMSKIEVNGDDAHPLYQWLKSEKGGLLGGKIKWNFTKYLLGRDGQVIDRYAPTTKPEKMTGDIEKALAGSKA

Crispr_ID: NZ_CP040695_2

• CRISPR_ID: NZ_CP040695_2
• CRISPR_location: 89859-89983
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP040695_2

Consensus_repeat	Method
GAGCCAACCTCGGCAATTGCGCGC	CRISPRCasFinder

spacers of NZ_CP040695_2

>2.1|89883|26|NZ_CP040695|CRISPRCasFinder
CGTGGGCCGGTCCGACCCGAGTGATC
>2.2|89933|27|NZ_CP040695|CRISPRCasFinder
TCCGGGCCGACGCGACCGGGAGAAACT

CRISPR arrays and Neighbor proteins around NZ_CP040695_2

CRISPR arrays

The CRISPR arrays of NZ_CP040695_2

>merge|NZ_CP040695|2|89859-89983|CRISPRCasFinder
GAGCCAACCTCGGCAATTGCGCGCCGTGGGCCGGTCCGACCCGAGTGATCGAGCCAACCTCGGCAATTGCGCGCTCCGGGCCGACGCGACCGGGAGAAACTGAGCCAACGTCGGCAATTGCGCGC

>NZ_CP040695|2|2|89859-89983|CRISPRCasFinder
GAGCCAACCTCGGCAATTGCGCGC	CGTGGGCCGGTCCGACCCGAGTGATC
GAGCCAACCTCGGCAATTGCGCGC	TCCGGGCCGACGCGACCGGGAGAAACT
GAGCCAACGTCGGCAATTGCGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_137293055.1|100137_100689_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_CP040695.2|WP_138874758.1|81307_82183_-|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl|CDD|223344
NZ_CP040695.2|WP_148240231.1|95630_97745_-|potassium-transporting-ATPase-subunit-KdpB	unknown	unknown	gnl|CDD|234905
NZ_CP040695.2|WP_148240230.1|92452_94993_-|DUF4118-domain-containing-protein	unknown	unknown	gnl|CDD|225115
NZ_CP040695.2|WP_137293065.1|88381_89317_+|topoisomerase-II	unknown	unknown	gnl|CDD|235521
NZ_CP040695.2|WP_138874769.1|100685_101558_+|hypothetical-protein	unknown	unknown	gnl|CDD|184927
NZ_CP040695.2|WP_148240232.1|97741_99406_-|potassium-transporting-ATPase-subunit-KdpA	unknown	unknown	gnl|CDD|377138
NZ_CP040695.2|WP_137293068.1|86274_86511_-|DUF1059-domain-containing-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137293072.1|82241_82496_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138874765.1|91343_91736_+|DUF4446-family-protein	unknown	unknown	gnl|CDD|379655
NZ_CP040695.2|WP_137293059.1|95001_95622_-|potassium-transporting-ATPase-subunit-KdpC	unknown	unknown	gnl|CDD|376890
NZ_CP040695.2|WP_138874766.1|91781_92456_-|response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP040695.2|WP_148240229.1|85291_86167_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138874762.1|86507_87404_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236600
NZ_CP040695.2|WP_138874759.1|82570_83764_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NZ_CP040695.2|WP_148240233.1|99690_100101_-|nuclear-transport-factor-2-family-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137293066.1|87536_88316_+|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176524
NZ_CP040695.2|WP_138874763.1|89313_89727_-|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|237999
NZ_CP040695.2|WP_138874760.1|83790_85152_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138874764.1|90033_91242_-|arginine-deiminase	unknown	unknown	gnl|CDD|234949

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_137293055.1|100137_100689_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.10031e-33
NZ_CP040695.2|WP_138874759.1|82570_83764_+|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	8.95093e-17
NZ_CP040695.2|WP_148240231.1|95630_97745_-|potassium-transporting-ATPase-subunit-KdpB	gnl|CDD|234905	PRK01122, PRK01122, potassium-transporting ATPase subunit KdpB.	0
NZ_CP040695.2|WP_148240230.1|92452_94993_-|DUF4118-domain-containing-protein	gnl|CDD|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP040695.2|WP_137293065.1|88381_89317_+|topoisomerase-II	gnl|CDD|235521	PRK05590, PRK05590, hypothetical protein; Provisional.	1.89055e-07
NZ_CP040695.2|WP_138874769.1|100685_101558_+|hypothetical-protein	gnl|CDD|184927	PRK14963, PRK14963, DNA polymerase III subunits gamma and tau; Provisional.	0.00129175
NZ_CP040695.2|WP_148240232.1|97741_99406_-|potassium-transporting-ATPase-subunit-KdpA	gnl|CDD|377138	pfam03814, KdpA, Potassium-transporting ATPase A subunit.	0
NZ_CP040695.2|WP_138874758.1|81307_82183_-|Fpg/Nei-family-DNA-glycosylase	gnl|CDD|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	3.02274e-52
NZ_CP040695.2|WP_138874765.1|91343_91736_+|DUF4446-family-protein	gnl|CDD|379655	pfam14584, DUF4446, Protein of unknown function (DUF4446). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 165 and 176 amino acids in length.	5.70601e-38
NZ_CP040695.2|WP_137293066.1|87536_88316_+|glycerophosphodiester-phosphodiesterase	gnl|CDD|176524	cd08582, GDPD_like_2, Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of uncharacterized bacterial glycerophosphodiester phosphodiesterase and similar proteins. They show high sequence similarity to Escherichia coli glycerophosphodiester phosphodiesterase, which catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	1.17295e-64
NZ_CP040695.2|WP_137293059.1|95001_95622_-|potassium-transporting-ATPase-subunit-KdpC	gnl|CDD|376890	pfam02669, KdpC, K+-transporting ATPase, c chain. This family consists of K+-transporting ATPase, c chain, KdpC. KdpC forms strong interactions with the KdpA subunit, serving to assemble and stabilize the Kdp complex. It has been suggested that KdpC could be one of the connecting links between the energy providing subunit KdpB and the K+-transporting subunit KdpA. The K+ transport system actively transports K+ ions via ATP hydrolysis.	2.80891e-87
NZ_CP040695.2|WP_138874762.1|86507_87404_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	6.33876e-63
NZ_CP040695.2|WP_138874766.1|91781_92456_-|response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.6694e-76
NZ_CP040695.2|WP_138874763.1|89313_89727_-|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	2.53619e-18
NZ_CP040695.2|WP_138874764.1|90033_91242_-|arginine-deiminase	gnl|CDD|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0

Protein sequences

>NZ_CP040695.2|WP_138874763.1|89313_89727_-|cyclic-nucleotide-binding-domain-containing-protein
MATFFDSFSAREIARISAHGRRVRLPEGWSPIWERTPADKAYIILDGSVSVRRGGTEIARLGAGDIVGEAAIVGRSLRTATVVALTPLSAIHFTDTDINELLEELPGFRDKLVALAQSRVGGAAAAGGAAGAGDGTG
>NZ_CP040695.2|WP_137293065.1|88381_89317_+|topoisomerase-II
MAKKSRTKARDHAPAETDGAVGPRQPCPCGSGKRYKACHGASGGADVYVARPFEGLPGECDIIALRELVPAATAPLTIKGHEDRTVRLCTLLPGAVPAMSRDSGEVWLGLQVQHQFGDPSRDLAAVLEAALAAEPGVVGLTTPPGPGHRLQDLVTDETLDVTVHDGFDYWVSDLDDSDELAGALEQANDAATPTSRLGSVEAAYWTDVGTKEHLRWVMPEPEDALLDALARLHESGDDVIVPDARLVGMFRAHGLLAPVWDLPVGTGAEVLEEPAAAFKKALDAALADTSPLTAEQRSARSGLANRQVTIR
>NZ_CP040695.2|WP_137293066.1|87536_88316_+|glycerophosphodiester-phosphodiesterase
MTTQVVAHRGASDENAEHTLGAYLAALESGADGLECDVRLTADGHLVCVHDRDLRRTAQARGLVSTMDLADLNELDFATWKNPWADLDDEAPERDESLDRVLTLRKLLETVADLDRRVEVAIETKHPTRYGGLVERRLVEMLKDFGWDVPGSPVRVMSFSFTALQRVERAAPGIQLVQLVDKAQHWSMLRRVVGPGWIMGPGIALLREQPRLGERITTAGHDMHVWTVNTDRDLERCLELGVKAVITDRPAYILERLGR
>NZ_CP040695.2|WP_138874762.1|86507_87404_-|sigma-70-family-RNA-polymerase-sigma-factor
MDQTQVFEAERPRLVGIASRVLGDHAEAEDVVQQAWLRMDRAASGTVIENVPAWLTTVTTRLCLDRLRSRTPVPVDDADLDDLDGVDGPDDRHGLAGDPADDVALADTVGLALHVVLDRLSPRERVAFVLHDSFGFDFPTIAAVLDTSPVAARKLASRARAKVAQPRPEDRLADWEVVDAFMAAARGGDLDRLLRLLAPDASVGADDAAVLAGTPRHVAGRDEVAAFFDGSAAAAFPVLVGGRPGAAWFHRGEARVVFDFTVVDGVVHTITFRAAPDVLADVVRRDGATPTHPTRRDR
>NZ_CP040695.2|WP_137293068.1|86274_86511_-|DUF1059-domain-containing-protein
MKTMTCRDLGGPCELAHHGESADDVINAQDQHLKEAEKAGDATHQEARDAMKGRWRHPKRSMGWYRDTKAAFAALPDD
>NZ_CP040695.2|WP_148240229.1|85291_86167_-|hypothetical-protein
MTRLRLAAAALAAAALLAPATAAHAKGGDDGGGDDRGGGTTSATAGDYAVTVNGRTYDPAPGRDVRVRDLAVTAGITVAGVHTRFTIDPATLGVHDYTLTGAPSPERMVTRPTVVFASKVPVLGPAQLRAPVLRQLEVRDGTLVVILATAAGKLKIQAKDAPQGGIFQMEPEFAGDVEVVHTLGPGLFYFVNSFTGKINFGDGVDAVASGPDAHQMLLGKDSPQVATKLFQDGRTTRWSVVPGGRLGGVLGEDAIELSQGATSCTSQCQAQNRVRGSLPVPPDPTDPTPLP
>NZ_CP040695.2|WP_138874760.1|83790_85152_-|hypothetical-protein
MDIDALKQAAIDAYMRSEGYQRQGGGSYFDYGLGFSATVGSDGTGVATYSTSSGSGMPVTSNVDLDYRTEWGEVRDRVDTALEQWQDDRLPEPSALNGGMVTAQAAVTALNMGSQNSYGGALGGYYKTISDNASEFRGAAMDAFNNSFVNQLPAVISNHGCLAAIVTEAWAAEKEIWTQARADRDTHVEKATAALDSYAESEGTSEIKFLLGLTGAALAGASAIASGGVTLPFALATAGITSLSATNDYVGELRLERSGDSYQDLMAAFESGLDDIDEAITQQETLVREGLENGWQTFEAHRALFDLTPRVSDDGDGGWGDETSIFDVTDAGALAVVIPGEAVVGSLSSGMKNLAHGLEDADPKIIAGAEEGGLLSPSAREVGLRYNGVAIMMWIVGDNTAASIRDLTWDVRNSEAMLRAIVTDFTNADAASQAGLDDLRGQLVGGSGEDPWR
>NZ_CP040695.2|WP_138874759.1|82570_83764_+|AAA-family-ATPase
MDPIRNPYAPGAGQRPPELAGRDEQLRAFDVVLERVSRGRPERSLVLTGLRGVGKTVLLNTLRSQAVRRGWGTGKLEARPDQPLRRPLSSALHQAVRELGHGREEEVEHALGVLRAFSERAAGGDAKLRDRWSPGITAPLVRGRADSGDVEIDLVELLTDLGGLAGETGRGIAVFIDEMQDLGPDDVSALCAACHEISQSGLPLIVVGAGLPHLPAVLSASKSYSERLFAYQRIDRLSRAEADRALTTPAAEEDAGFTPEALEALYAATGGYPYFVQAYGKTVWDLAPASPITAADVDVATPEADRELGVGFFGSRYERATPGERDYLRAMAEATPDPDDPAGSVATADVAAVLARKPQALSPARDALLKKGLIYSGERGRIAFTVPHFGRYLREQA
>NZ_CP040695.2|WP_137293072.1|82241_82496_+|hypothetical-protein
MSTPVRALRSPGAIFLDPRGDERALRVSWHTDGGPDGVVVLSMWRDNLCVATFRLAVDEVPDLIAMLREGLDVAYAATRSARSA
>NZ_CP040695.2|WP_138874758.1|81307_82183_-|Fpg/Nei-family-DNA-glycosylase
MPELPEVEALALDLKGRLDGRAIATVHLAAFSALKTYDPPVTALTGMLVDDVTRHGKFLDIDVSGLHLVLHLARAGWVRWREEVPALPPKPSNKSPLAVRVVLDDGTGLDITEAGTKKSLAMYVVRDPLEVRGIASLGPDPLSPDFTRDALEAILRSEGRKQIKGVLRHQGTIAGIGNAYSDEILHAARISPYRPASAIADDEDGGLDVLYAAVRTTLGDAVERSRGLAASELKGEKKSNLAVHGRTGKACPVCGDTVREVSFADSSLQYCPTCQTGGKPLADRRMSKLLK
>NZ_CP040695.2|WP_138874764.1|90033_91242_-|arginine-deiminase
MTLGADSEVGRLRTVMLHRPGGELTRLTPRNNDRLLFDGIPWVARAQEEHDAFAQALRERDVEVLYLTDLLTETLADDGARAAAISDALAGLDLGDTMRRYLQGFLGEATPAELTTYLTAGIRNDEVRGGFGLVTSLLTHDDFLIDPLPNLLFTRDSSVWVRDHVAITSLAMPARKRETELTELIYTRHPRFVGTPRIHGSHYEHVEGGDVLLLAPGVVAVGVGERTTPAGVERLARQVFDDDLAHTVLAVPIAQERATMHLDTICTMVDVDKMVVYENVADSLVAFTVTPDGQSDDGELRLSVADSRPFLEAAADAMGIDVLHRIDTGLDPVTAEREQWDDGNNTLALAPRVAVAYERNDATNDRLEQAGIEVVRIAGSELGSGRGGPRCMSCPIERDPLV
>NZ_CP040695.2|WP_138874765.1|91343_91736_+|DUF4446-family-protein
MLEVLAVVAVVLAAAALVLAVVALRRTSRRADGSDLPQDLHGLRQEVAALRAEGADVLRHLAVVRYDAFNDVGGHLSWSLALLDDHGDGVLLSSIHGRSEARSYAKSVTGWSCEQQLSPEEDEAITLARG
>NZ_CP040695.2|WP_138874766.1|91781_92456_-|response-regulator
MRVLVVDDEPALARALAINLRAHGWDVVTAADGRGALDAAATTHPDVVLLDLGLPDLDGTEVISGLRGWTTVPIVVLSARQHGEDKVEALDLGADDYVTKPFAMNELMARLRAAVRRAQEAAPTAALVQVGDLAIDLARKRVAKAGADVRLTPTEWAFLELLARNVGRLVPREQVLREVWGPAYLHETHYLRVYAAQLRRKLEDDPSAPRHLRTSAGLGYTLEP
>NZ_CP040695.2|WP_148240230.1|92452_94993_-|DUF4118-domain-containing-protein
MEQRRGRLTVYLGAAPGVGKTCAMLDEARRRVERGTDVVVGLVETHGRAHTEARTEGLEVLPRRTVEHRGTTFTDLDVDAVLARRPAVVCIDELAHTNVPGSAREKRAEDVEVIRAAGIDVVTTVNIQHLESLNDQVERITGVRQRETVPDAVVRSADQIQLVDMAPEALRRRMAHGNVYRPENVDASLTSYFRVGNLTALRELALLWLADRVDDALGDYRRAHRIDHPWPTKERVVVAVTGGPESETLIRRGAKLAERAVGSELLAVHVIADDGLRDPGERQVARAQQLVATLGGTFHTVVGEDVARAVVDFATGADATMLVVGVSRHGRLRRLLTGSSGDRIASLAGAVDVHLVTHAQAGRATRARGAGSSLSTRRQLAGWAAAVVLPVVLTWLLQRFEDTDQLPLAEMLLLAGTVLVALVGGLLPALAAAVVSFFTLNWFFTPPTGVLTVAEPANFVALLVYVAVAGGVATVVDRASRRAAEATLARTEAATMGALSRSVLTGHDTAEAVVARLRETFGQDAVSLLARTASGWQVVAASGGPCAATPDEGDTRVRVDDDHVLVLTGDPLRASDQRVLEGFAVQTSLVLEYRRLRTREDRAAALESAEATSTALLRAVSHDLRTPLATMRTSVDGLVGGGELVGPDDRAELVRSLDDGIDRLERLIDHLLDLSRLEAGLLQPVLRDRSLDEVLPLAVAGHPPGAVSLEVDESVPMVRTDVGMLERVVANLVGNAVRASRSTGATPVRVLAHVLPGTVEVLVVDRGPGVPAAQRERMFAPFQRLDDSSVGGLGLGLAVARGLTEALGGTLEAEDTPGGGLTMVLAVPRAEPPTGTGSGTGTGVGG
>NZ_CP040695.2|WP_137293059.1|95001_95622_-|potassium-transporting-ATPase-subunit-KdpC
MKDLSSLFRFSLAGLRLLVAMTLVLGLGYPLLVTGIARVAAPWQADGSLVTVTGAHTTDPDEAVGSALLGQLVDDPTLFQPRPSAAGDGYDPLSSYGSNLGPESPELVAAITERRAEVAAREGVAPDDVPPDAVTASASGLDPHISPAYAAIQVARVARGTGLAPDDVRALVEEHTEGRTLGILGEPRVDVLGLNIAVLAAAGAAG
>NZ_CP040695.2|WP_148240231.1|95630_97745_-|potassium-transporting-ATPase-subunit-KdpB
MSTPASTTPTATTPTARGSSVLTVAQLAAALPGALRKLDPRELLATPVMLVVEVGAVATTVMSVLDPSTLGWLVTLWLWLTVVFGTLAESVAEGRGKAQAASLRELQTETPARRVRGAAGALPHTDTLADLPTDLPTDEVPSTSLHAGDVVVVEAGERIPGDGDVVAGVASVDESAVTGESAPVIRESGGDRSAVTGGTVVLSDRIVVKITSEPGQSFVDRMIALVEGSERQRTPNEIALNVLLSSLTVVFVVVCGSLYFLADHSGAHQSPLVLTALLVCLIPTTIGALLSAIGIAGMDRLVRRNVLAMSGRAVEAAGDVDVLLLDKTGTITHGNRQAAELLAVPGVTSAELAEAALLSSLADETPEGRSIVTLVGGAVATPPGATFVPFSAATRMSGLDLPGRTLRKGAGSAVAQWVHSTGSPAAHPSVAAIEAHVQHVSESGGTPLVVAEQVGSAPARLLGVIHLKDVVKDGIRERFEELRAMGIRTVMITGDNAVTAAAIAREAGVDDVLAEATPEDKLALIRREQQGGRMVAMCGDGTNDAPALAQADVGVAMNTGTTAAKEAGNMVDLDSDPTKLLDVVEIGKQLLITRGALTTFSVANDVAKYFAILPAMFVVAFPDLDVLNVMRLSSPESAIVSAVVFNALVIVALIPLALRGVAYRPASASALLQRNLLVYGVGGLVAPFLGIKLLDLVISHIPGL
>NZ_CP040695.2|WP_148240232.1|97741_99406_-|potassium-transporting-ATPase-subunit-KdpA
MSEIVPTLLQVAVLVAALALTVPPLGRLLAHAYTSPRHLAVERVTYRVLRVDPDADQHWRTYAMSVLGFSLVGVLVLFAFGRLQQHLPLSLGFAALPPDGAWNTAVSFVTNTNWQWYSGEAALGHLMQMSGLTVQNFLSAGVGMAVAAAFARGLARRGGAGRVGNFWADLVRTVLRVLLPIALVAAVLLVATGVVQNLAGPHLVDTLTGGHQAITGGPVASQEAIKELGTNGGGFYNANSAHPFENPTPLSNLFEIFLILLVPFAMAWAFGLIVGDRRQGVAVLTVMGLLLAVSVALLTWAEMAGPGTAPQLAQGALEGKEQRFGTAGSALFAAATTGTSTGAVNTMHDSLTAPGGGVALFNMMLGEIAPGGVGSGLYGMLVLAVVTVFLCGLMVGRTPEYLGKKIGQREIVLVAAYVLTTPVLVLVGSAVALTASDGLAGLQESGPHGLTEAVYAVTSASNNNGSAFGGLTSGTPFWNTLLGLCMLLGRFLPMVVVLALAGRFATQPRLPAGAGTLPTHRPLFVVLLAGVALVVVGLTYVPVLALGPIVESLS
>NZ_CP040695.2|WP_148240233.1|99690_100101_-|nuclear-transport-factor-2-family-protein
MTTPAPVQAWHRIAAARDEASLADLDALLAEECVFRSPAVHTPQEGKPVTTAYLLAAMAVLGPTLRYLDEWYAVAEDGGGSAVLEFGCEVGGRSVHGVDMLRWGADGRLTSFTVMIRPAQGLEAVIAAMGAELSRA
>NZ_CP040695.2|WP_137293055.1|100137_100689_+|SigE-family-RNA-polymerase-sigma-factor
MRRLTSMTTTSDLAAGSRRPLAAGDLAQLYAAHRLSLVRLAILLVDDRASAEDVVQDAFASLAGRLHRLRDPDAALGYLRTSVVNGSRSALRRRRTARAYVPPAEAEPPGPDDRAVLAEEHREVLAGVDRLAPRQREVLVLRYWSGLSEAEIAEACGISRGAVKSTASRALDALEQILKGEGR
>NZ_CP040695.2|WP_138874769.1|100685_101558_+|hypothetical-protein
MNTLESRLAEALEARAEQVQAADLGPGRVPATVSPLRRRVQVGGAVAAAAAVAAAAVVAVSVMNDDGGTSPSPAPRPTVSDTANPTTPPAPGPTSSTNAPEDRLSDLLPFDTTQYVEPDTTVRFGDGETATITGGELVVSGSGSVLRGPLEGVDPREATSITRVALGQVGNGYLLGQTLGGDSLVQELYVAGDGGGLVLARAPEDVPFGFGYAEGFPDGFLTWTTGDGSGLFTRVQLGDPAGNRWQVYRWEVTGPGEGGGPESLARDLVPTDLGVACFGPGNPPQSVTPC

Crispr_ID: NZ_CP040695_3

• CRISPR_ID: NZ_CP040695_3
• CRISPR_location: 318064-318150
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_3

Consensus_repeat	Method
ACCGGAGGTTGAGCAAGCGAGCGC	CRISPRCasFinder

spacers of NZ_CP040695_3

>3.1|318088|39|NZ_CP040695|CRISPRCasFinder
CAGCGAGCGCCGACGAAACCCCGGTCCGCGACCTCGGGG

CRISPR arrays and Neighbor proteins around NZ_CP040695_3

CRISPR arrays

The CRISPR arrays of NZ_CP040695_3

>merge|NZ_CP040695|3|318064-318150|CRISPRCasFinder
ACCGGAGGTTGAGCAAGCGAGCGCCAGCGAGCGCCGACGAAACCCCGGTCCGCGACCTCGGGGACCGGAGGTTGACCAAGCGAGCGC

>NZ_CP040695|3|3|318064-318150|CRISPRCasFinder
ACCGGAGGTTGAGCAAGCGAGCGC	CAGCGAGCGCCGACGAAACCCCGGTCCGCGACCTCGGGG
ACCGGAGGTTGACCAAGCGAGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138874896.1|327204_328443_-|DUF222-domain-containing-protein	unknown	unknown	gnl|CDD|367155
NZ_CP040695.2|WP_138874895.1|319551_320484_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240281.1|325531_327208_+|DUF853-family-protein	unknown	unknown	gnl|CDD|283518
NZ_CP040695.2|WP_138874889.1|312325_312799_+|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl|CDD|380217
NZ_CP040695.2|WP_137295655.1|320516_320975_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137295656.1|322588_323044_+|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240040
NZ_CP040695.2|WP_137295658.1|324650_325295_-|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379163
NZ_CP040695.2|WP_137292874.1|313966_314140_+|CsbD-family-protein	unknown	unknown	gnl|CDD|283241
NZ_CP040695.2|WP_137292872.1|315670_316531_+|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NZ_CP040695.2|WP_138874891.1|313328_313910_+|hypothetical-protein	unknown	unknown	gnl|CDD|380217
NZ_CP040695.2|WP_138874890.1|312795_313332_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240280.1|318187_319555_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240950.1|321080_322259_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|235596
NZ_CP040695.2|WP_137295659.1|325183_325486_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl|CDD|227737
NZ_CP040695.2|WP_148240279.1|316527_317952_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|283431
NZ_CP040695.2|WP_137292878.1|311921_312212_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137295657.1|323141_324635_+|potassium/proton-antiporter	unknown	unknown	gnl|CDD|235410
NZ_CP040695.2|WP_138874892.1|314206_315580_-|FAD-binding-protein	unknown	unknown	gnl|CDD|273050
NZ_CP040695.2|WP_137292879.1|311586_311925_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_134767929.1|312225_312402_+|DUF2273-domain-containing-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_148240281.1|325531_327208_+|DUF853-family-protein	gnl|CDD|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP040695.2|WP_138874889.1|312325_312799_+|Asp23/Gls24-family-envelope-stress-response-protein	gnl|CDD|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	0.00137792
NZ_CP040695.2|WP_137295658.1|324650_325295_-|LytR-C-terminal-domain-containing-protein	gnl|CDD|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	2.25864e-10
NZ_CP040695.2|WP_137292874.1|313966_314140_+|CsbD-family-protein	gnl|CDD|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	0.000341295
NZ_CP040695.2|WP_137292872.1|315670_316531_+|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.1315e-43
NZ_CP040695.2|WP_138874892.1|314206_315580_-|FAD-binding-protein	gnl|CDD|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	9.03225e-125
NZ_CP040695.2|WP_148240950.1|321080_322259_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	1.80106e-147
NZ_CP040695.2|WP_137295659.1|325183_325486_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl|CDD|227737	COG5450, COG5450, Transcription regulator of the Arc/MetJ class [Transcription].	7.82689e-08
NZ_CP040695.2|WP_148240279.1|316527_317952_+|VWA-domain-containing-protein	gnl|CDD|283431	pfam05762, VWA_CoxE, VWA domain containing CoxE-like protein. This family is annotated by SMART as containing a VWA (von Willebrand factor type A) domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria.	1.67996e-33
NZ_CP040695.2|WP_138874896.1|327204_328443_-|DUF222-domain-containing-protein	gnl|CDD|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	5.26302e-19
NZ_CP040695.2|WP_137295657.1|323141_324635_+|potassium/proton-antiporter	gnl|CDD|235410	PRK05326, PRK05326, potassium/proton antiporter.	0
NZ_CP040695.2|WP_137295656.1|322588_323044_+|NUDIX-domain-containing-protein	gnl|CDD|240040	cd04684, Nudix_Hydrolase_25, Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	7.08351e-29
NZ_CP040695.2|WP_138874891.1|313328_313910_+|hypothetical-protein	gnl|CDD|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	5.43962e-07

Protein sequences

>NZ_CP040695.2|WP_148240279.1|316527_317952_+|VWA-domain-containing-protein
MSTRSGLVDRHIAFVEALRGAGLSVSLAEDLDAIAVLGALDWTDRDVVREGYAASLVKRQAQRPTFEALFDLYFPRMVGGGAASLDPDAGSGEESGEESGDDVAASPVRDNAAALSAFREQLAEALAADDRQRLQQLAAEMVGRFGAMPGRGPGLSSWSAYTALQRVAPSELVAQIVAGLLAEGLTEEEAERGAGRRVGAFTAQVEADARRRIAEEKGADHVANVALRPSIERLDFMAARRSDLEEMRREIYPLARRLATRLTQEQHARRRGPLDFRRTVRASMSTGGVPIATHHRPKRPHRTELVVLCDVSGSVANFAQFTLLLVFALRDQFQKVRAFTFIDQVHEVTPYFKPGADVVDVMSDLAASTTHAALWGRTNYGRALGRFAEEHPDAVGPKTSLLVLGDARSNYSDLNEAVLRELAGTARHAWWLNPEHRRHWGTGDSAAAAYGDIVPMVECRNLTQLAEFVHDLTT
>NZ_CP040695.2|WP_137292872.1|315670_316531_+|MoxR-family-ATPase
MSWFASPTDASARLHEVGYLADGATSTTSYLAGALEKPLLVEGPAGVGKTELAKAVARATGAELVRLQCYEGLDEARALYEWNYKKQLLRIQASHGQEWDATHDDIFTEEFLLTRPLLTAIQRETPTVLLIDEVDKTDVEVEGLLLEVLSDFQVTIPELGTVTATRRPFVVLTSNASRELSEAVKRRCLYLHLDYPDAEREREIVASQVPGLDDRVTAQLVATVARLRELELKKAPSIAESVDWARTLVALEIGDLDAKAIADTLGVILKHRSDHDRAVKELKLAR
>NZ_CP040695.2|WP_138874892.1|314206_315580_-|FAD-binding-protein
METTPPDLAALRGALPAGALVEDPDRMAGYRWDRARDPGAGVPLAVVRATCTADVQAAVRYAAAHGVPVVPRGAGSGLSGGASAVDGCLVVSTERMRAIEVDPVTRTAVVEPGLLNAEVKAAAAAHGLWYPPDPSSYEICSIGGNVATNAGGLCCVKYGVTTDYVLGLTVVLADGTAVELGGPRLKDVAGLSLTKLFVGSEGVLGVITRVVLRLVPAQRPPSTLVATFPTLDGATDAVLAITRRMRPSMLELMDRVTINAVEDETRMGLDRTAEAMLVIQTDEPADHAAVEVTEITADCESRGAVEVFATDDVAVGEAFVVARRMAIPAMEKKGFLLLEDVGVPLPALGALVRGIAAISRDRAVTIAVIAHAGDGNTHPLIVFDAADPDESDRAQVAYGEVMRLAIRLGGTITGEHGVGRLKRPWLGDYLGPDALELNRRVKTALDPQGILNPGALL
>NZ_CP040695.2|WP_137292874.1|313966_314140_+|CsbD-family-protein
MGIADKAKNAAQDALGKAKEVVGDAKGDDALKAEGKADQGEAKTKNKVEDVKDVFKG
>NZ_CP040695.2|WP_138874891.1|313328_313910_+|hypothetical-protein
MTRRLLLLDRLAVLVVGLALVALGLLAADWQHGWVLHLDDRLDTGRLDDVLDAAWWPWTLAAVGVVLGLAGLAWLLAHLRRSGPSVMRLRASDGSGHVEADLASAATAAAQRLGTLAPVTGVRGTSRTVRSRTVLELRGHVDPSADVATLTEAAEVCAADVAAAFPDDDVVCRVVLDAPRRPRTGRSTRVRVR
>NZ_CP040695.2|WP_138874890.1|312795_313332_+|hypothetical-protein
MSAPTDRTPPRARPVAALAAPVLALALVAVAVVAVRDLLVDRGRVGGTPWSRDLVDAVDGLTASTALTVAGLAAAVVGLLLVVAALLPGRRTHLRGSAAADLWVSPGALAALAQTVADRSPGVVSAAATRVGRRRVTVEVVAREGEPGVRDAVRAALDDGPGALTAATVGVRLQEVPR
>NZ_CP040695.2|WP_138874889.1|312325_312799_+|Asp23/Gls24-family-envelope-stress-response-protein
MSATSSAATSTASSTSRRWCEDVVAEPAVEGTAGPATLDRARPDDRGTLEVRVRAIQHVVEQAVLSTPGTVAHRTALGRLRGSNSPHADITMQGRSARVAVDVACVWPCHVAGIAARVRDTVRSEAARITGVHLHTVDVTIHTLGAAEVDQERRRVE
>NZ_CP040695.2|WP_134767929.1|312225_312402_+|DUF2273-domain-containing-protein
MTTSTIGLIAGLLLTIAIVAGGFTGFLLAVVLGGVGYLVGGHVDGELDLAALVRGRRG
>NZ_CP040695.2|WP_137292878.1|311921_312212_+|hypothetical-protein
MSDPQRDVRARRRALAKEHHPDVGGDPAEFVRAMRGLGGSAGDDGPDAVTSGTTTVAPSRVARSARRVRGAGTTLVATVRRRLPRSFPGSRRYGHL
>NZ_CP040695.2|WP_137292879.1|311586_311925_+|hypothetical-protein
MSSPPSSPTTPADAAGSEPADRVAAAVLAVAGVDGLHGGAHGEVATYLPGRRVVGVRLRDPGCAVHVVLAWGVPIAGTAELVRRAVNGLVAGPVDVTIEDVSPPTVPAGPAS
>NZ_CP040695.2|WP_148240280.1|318187_319555_-|hypothetical-protein
MTGRAEEDPTSQASVVAAAAAEQRRVPATDSEAADLADRYDRMMRLASLFDGSGEEMRQRAQLGADVVADPAFAESAPLSPATHAQVEDDVRAATTGKHGLLARSIELDADALVLRATVLTYRWIDELQIAAYKTLGSIAGRAIGYLAPEVALGGAIVSAGLIETDALDRDGVAAYLNELADSNPELMEHVTSGGGGLLDGLQMRALLTAGILSGDHGRLAGRGGLRAIDVEPFPSTFAASLRDVAGGLVDAASELPDAATAPSPGGAPRNLAELLTALHETRTTVVVRSVAPSRYIAYLHGPDGGTGGRLRLVGGDHSSYAGHVVRSIEQAIGSDTDARVMLVGSAQGGVTAAEVAAAPASTRFVIDQVVTTGAPSAHVPRIPESTRMLSLEDRSDPVALLGSLMNSGASNRVTVVYDGGADGYVDGGRAADAANHPALVEEIARITAMGYLAG
>NZ_CP040695.2|WP_138874895.1|319551_320484_-|hypothetical-protein
MTTIDLSTPAPPPSSLFDALPRRVALTLLELQLVAERAGGAPLPFDVRAPDADGAPSLEDRLGASRGSAQDQAYLAAVAALHDPEVSLTRRGLLVNGVVDDGLAGAVGLLATPTYALDIDVAVEAVQVKAWHRANDDAVATLATSDGIVFELAWFPTAAWPDELGRVGVVPEDLAMRESSVPSFLDLPYELADAAVEAGASGRTDVLQVLTAQHADQVVDADGRPVPAAEVPGLLQALGAEAQGRLRVLVADVSREPTSVVGVRSWVLLADGWRTLHPHQSEGGTRVEIRAVQPTELAVDLAPVLADVAS
>NZ_CP040695.2|WP_137295655.1|320516_320975_-|hypothetical-protein
MYGDTDVMRRRADQLREQATDIRTMADQLVAHTEVVGWSGRAADSMRVRVTERASHLRAAAADHDAAAEALDKHVLEVDTAKDAIAEVERRAGDLVAEARTRLARVEQANADADGAPGGARIEPDHDDVVLAAFDPPPAGHRDWLAVELPGL
>NZ_CP040695.2|WP_148240950.1|321080_322259_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MQAAQRANVPPFHVMDLLAAGTERQRTHGDLVDLLAGQPSTGAPRAVNDEAVRLLRSGEPLGYTPATGIRELREAIAGHHRRTRGIDVDPDEVVVTTGSSGGFLLAFLAAFEVGDRVAIARPGYPCYRNVLAALGCEVVEVPTGPGTRFQPTVDQVAELVASPGGLRGLVVASPANPTGTMLLPSELAALATYCDENGVQLISDEIYHGIEYPAAGAERLARSAWETSREAVVFCSFSKYFSMTGWRIGWMLVPERLRRAVDVLTGNFTICPPVLAQRACVAAFGDDAYAELDGHVARYAGNRRLLLDGLARLGVTGLAPADGAFYAYADVGHLTSDSMTFAHDVLARTGVALATGVDFDTVDGGRFVRFSFAGPESRIVEALDRLAPVLAP
>NZ_CP040695.2|WP_137295656.1|322588_323044_+|NUDIX-domain-containing-protein
MHYTQYDTRVATYALILDDQDRILLTWWNGEGRFTPGWSLPGGGVDLEEGLEESLVREVREEAGYDVVVGAPLTTHSWFRHDEPRPFKAVRVIFDATIVGGVLGTLEVGGSTDFAQWMPIADVAAQPSRAEIVDVAVSAHLARTGRGVEDR
>NZ_CP040695.2|WP_137295657.1|323141_324635_+|potassium/proton-antiporter
MTFDLHQFDQFVLIGSVVTLAAILAVRLSSRAGLPSLLIYLLMGVVLGESVIGIDFEDAELAHALGFGALAIILAEGGLTTSWREARPAMRLGLSLATVGIAVSVAVVAIGSHYLLGLPWELAVLLGAVCSPTDAAAVFSVLRVVPLPKRLIGSLEAESGLNDAPTVVLVTLISTGAVADQGVLGMFAIIVFELVVGVAFGLGAGFGGAWLMRRVALPSSGLYPLAVLCLAFLSYGASVAVHASGFAAIYVAALVLGNADLPHRGTTRSFAEGIAWLAQIGLFVMLGLLLSPARIDLDVVVLAVTAGLILTFVARPVSVLVSSVVQPMPWREVTFLSWAGLRGAVPIVLTTIPLAEGVDDAEKLFDIVFVIVIVYTLLTGPTLPLVARVLGVDRKSEPRDLDLEAAPLERVQADLLQITITPLSHLHGVEVGELRLPKGASVSLVIRAGETLVPERRTVLKHGDDLLVVTPRKLRERTEERLRQVSARGRLGQWLDE
>NZ_CP040695.2|WP_137295658.1|324650_325295_-|LytR-C-terminal-domain-containing-protein
MAGRALPRGRAAPRAARRPAPAQRPARPRPRDGRRAVSGPQDVSPGLLGHVRTIVTLAVLALLLALGVTRGLNAVSEPFPESADPPLCVDDDLTAGDILRPAQLTVTVLNAGERTGLAGVTLDDLEARGFARGRISNLTGEDVASVEIWSPEGRTPAVRLVAGYLTGRVEVVERGSSADGITVVVGDKFPGVRAGKEQLVLRSDVTVCSPASLG
>NZ_CP040695.2|WP_137295659.1|325183_325486_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MIFKRVGDGRPYPAHGLTSSAWANLPPRQVRLNELVTTKDTLQLAALLEEDGTFYGDLFAHVVRWQGELYLEDGLHRALRAALHQRNVLHARVLEMDGVR
>NZ_CP040695.2|WP_148240281.1|325531_327208_+|DUF853-family-protein
MTTTPGGSPADQPAPVEPPAEPAAPAGDPAVAPTPLEAAVAAGYAFEGPALELGGLMADAETLSPVPVRIPLGMLNRHGLVAGATGTGKTKTLQLLAEQLSAAGVPVFAADIKGDLSGLATPGEGGEKVTARAASVGQTWAATGYPVELYALGGEGTGIPLRVTMTAFGPVLLSKVLGLNDTQESSLGLVFHYADKAGLPLLDLADLRAVVSHLTSDEGKPELKALGGLSPATAGVILRELIAFSDQGADAFFGEPEFESADLLQVTPEGRGLISLVELPNLQDRPAIFSTFLMWLLADLFHDLPEVGDIDKPKLVFFFDEAHLLFNDASKAFLDQIAQTVRLIRSKGVGVFFVTQSPTDVPDAVLAQLGSRVQHQLRAHTPNDAKALRATVNTYPGSLYDDLGAVITSLGIGEAVVTVMNERGAPTPVAWTRLRAPESLMGPSDPAAMQATVAASPRHAKYATAVDRESAREKLAARLEEGARKKAEEDAAAERAEEATGTGAGRSTSTGGARKPARKPARDEGGLVHDVVSSGAFKDFVRTAAREIARGMFKTGRR
>NZ_CP040695.2|WP_138874896.1|327204_328443_-|DUF222-domain-containing-protein
MSKHPGDRHDGHPVARFVALLEAELAALVDAPTWSLDPATTADLVPRLAGLVAGVQELEARVVGHAGTLDLPGSIGARSLAAWLARTTRVTGAEAARKARLADDLAAHESVRVAMASGRVHGEQAKVIAAAVGDLDGEHFSWREKAEAHLLDEAAHHDAHDLKTLGRRILETLDPDKADEHEARLLEAEEARARKRTALTMWDDGEGLAHGRFTMPSAQASMLRKALTALAAPKHVRAEHGAGSYDHERPTAERLGQAFCEYVEHYPADQLPTMGGVNATVVVTMTLDALHGGLAAAHLDTGTALSPTEARRLACEAGIIPAVLGSQGQVLDLGRRRRFHTPAQRLAIGLEQRHCQHPACTTPAAYCHTHHAVPWSEGGSTDTRDAVLLCPFHHHQTHRAAHATEEAHPLRV

Crispr_ID: NZ_CP040695_4

• CRISPR_ID: NZ_CP040695_4
• CRISPR_location: 418384-418539
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP040695_4

Consensus_repeat	Method
GGCCAGCAGGGCTACGGCCAGCAG	CRISPRCasFinder

spacers of NZ_CP040695_4

>4.1|418408|21|NZ_CP040695|CRISPRCasFinder
CCGCCCGCCCCGGGCGGGTAC
>4.2|418453|21|NZ_CP040695|CRISPRCasFinder
CCCGGCGGCCAGCAGGGCTAC
>4.3|418498|18|NZ_CP040695|CRISPRCasFinder
CAGGGCTACGGACAGGGC

CRISPR arrays and Neighbor proteins around NZ_CP040695_4

CRISPR arrays

The CRISPR arrays of NZ_CP040695_4

>merge|NZ_CP040695|4|418384-418539|CRISPRCasFinder
GGCTACCAGTCCTACGGCCAGCAGCCGCCCGCCCCGGGCGGGTACGGGCAGGGCGGCTACGGGCAGCAGCCCGGCGGCCAGCAGGGCTACGGCCAGCAGCCCTACGGCGCCCAGCAGGGCTACGGACAGGGCTACGGACAGGACTATGGCCAGCAG

>NZ_CP040695|4|4|418384-418539|CRISPRCasFinder
GGCTACCAGTCCTACGGCCAGCAG	CCGCCCGCCCCGGGCGGGTAC
GGGCAGGGCGGCTACGGGCAGCAG	CCCGGCGGCCAGCAGGGCTAC
GGCCAGCAGCCCTACGGCGCCCAG	CAGGGCTACGGACAGGGC
TACGGACAGGACTATGGCCAGCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_148240304.1|424213_425788_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP040695.2|WP_148240953.1|422309_422960_+|dTMP-kinase	unknown	unknown	gnl|CDD|234814
NZ_CP040695.2|WP_148240300.1|408514_408739_+|DUF4244-domain-containing-protein	unknown	unknown	gnl|CDD|379429
NZ_CP040695.2|WP_138874941.1|426460_427447_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|184242
NZ_CP040695.2|WP_137295008.1|408735_409143_+|pilus-assembly-protein	unknown	unknown	gnl|CDD|377921
NZ_CP040695.2|WP_137295013.1|423066_424200_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|236134
NZ_CP040695.2|WP_137294993.1|429501_430425_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP040695.2|WP_138877025.1|427443_428373_-|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
NZ_CP040695.2|WP_137295004.1|412971_415281_+|sodium-translocating-pyrophosphatase	unknown	unknown	gnl|CDD|234827
NZ_CP040695.2|WP_138874942.1|428390_429437_-|AAA-domain-containing-protein	unknown	unknown	gnl|CDD|223786
NZ_CP040695.2|WP_138874938.1|417363_418119_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375319
NZ_CP040695.2|WP_148240305.1|425841_426453_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137295006.1|409510_409822_-|hypothetical-protein	unknown	unknown	gnl|CDD|119324
NZ_CP040695.2|WP_137295007.1|409139_409523_+|hypothetical-protein	unknown	unknown	gnl|CDD|274799
NZ_CP040695.2|WP_148240952.1|409831_412171_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|274800
NZ_CP040695.2|WP_148240301.1|415393_416860_+|methyltransferase	unknown	unknown	gnl|CDD|368316
NZ_CP040695.2|WP_137294992.1|430511_430694_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137295005.1|412420_412759_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP040695.2|WP_138874937.1|416896_417253_-|DUF1330-domain-containing-protein	unknown	unknown	gnl|CDD|377765
NZ_CP040695.2|WP_148240303.1|419542_422299_+|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|236048

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_148240304.1|424213_425788_+|alpha/beta-fold-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	5.9218e-31
NZ_CP040695.2|WP_148240953.1|422309_422960_+|dTMP-kinase	gnl|CDD|234814	PRK00698, tmk, thymidylate kinase; Validated.	1.29345e-81
NZ_CP040695.2|WP_148240300.1|408514_408739_+|DUF4244-domain-containing-protein	gnl|CDD|379429	pfam14029, DUF4244, Protein of unknown function (DUF4244). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 66 and 95 amino acids in length. There is a conserved EYA sequence motif.	1.53413e-10
NZ_CP040695.2|WP_138874941.1|426460_427447_-|VWA-domain-containing-protein	gnl|CDD|184242	PRK13685, PRK13685, hypothetical protein; Provisional.	7.80675e-93
NZ_CP040695.2|WP_137295008.1|408735_409143_+|pilus-assembly-protein	gnl|CDD|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	0.00162035
NZ_CP040695.2|WP_137295013.1|423066_424200_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|236134	PRK07940, PRK07940, DNA polymerase III subunit delta'; Validated.	6.6011e-156
NZ_CP040695.2|WP_137294993.1|429501_430425_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.2608e-34
NZ_CP040695.2|WP_138877025.1|427443_428373_-|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.68995e-16
NZ_CP040695.2|WP_137295004.1|412971_415281_+|sodium-translocating-pyrophosphatase	gnl|CDD|234827	PRK00733, hppA, membrane-bound proton-translocating pyrophosphatase; Validated.	0
NZ_CP040695.2|WP_138874938.1|417363_418119_+|helix-turn-helix-domain-containing-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	1.93405e-24
NZ_CP040695.2|WP_138874942.1|428390_429437_-|AAA-domain-containing-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.98146e-83
NZ_CP040695.2|WP_137295006.1|409510_409822_-|hypothetical-protein	gnl|CDD|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	0.00412289
NZ_CP040695.2|WP_137295007.1|409139_409523_+|hypothetical-protein	gnl|CDD|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	7.65392e-08
NZ_CP040695.2|WP_148240952.1|409831_412171_-|DEAD/DEAH-box-helicase	gnl|CDD|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	0
NZ_CP040695.2|WP_148240301.1|415393_416860_+|methyltransferase	gnl|CDD|368316	pfam05175, MTS, Methyltransferase small domain. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.	2.61053e-23
NZ_CP040695.2|WP_137295005.1|412420_412759_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.26984e-29
NZ_CP040695.2|WP_138874937.1|416896_417253_-|DUF1330-domain-containing-protein	gnl|CDD|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	2.28798e-29
NZ_CP040695.2|WP_148240303.1|419542_422299_+|type-I-DNA-topoisomerase	gnl|CDD|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0

Protein sequences

>NZ_CP040695.2|WP_138874938.1|417363_418119_+|helix-turn-helix-domain-containing-protein
MTQESGVLLREWRRRRNLSQLDLAHRAGVSSRHVSFIETGRARPTSAMILRLCDQLAVPLREQNRCLLAAGYAPAHPEHALDAPPMAEVAAAIDAILAAHLPFPALVVDPGWDLVAANDALYALIGEVAPRLVEPPVNVVRLSLDPEGLAPRIVNLPEWRAHLLARLRREHDADHDPRLAALLAELDDGAGEPGTTTPGLLVPLLLRVGDTVLSLLSTTTVFGTPREVTVSELAIEAFYPGDDETRRALLA
>NZ_CP040695.2|WP_138874937.1|416896_417253_-|DUF1330-domain-containing-protein
MTEQTRSTPAYAVAHLRQVGVGDAIIEYLTRIDATLAPYGGRFLVHGGPVTALEGVWDGDVVVIAFPSSGAARAWYDSAEYRAILPLRLDHAHSVAAIVEGVPEGYRATDKLAALQGA
>NZ_CP040695.2|WP_148240301.1|415393_416860_+|methyltransferase
MNPATAPALREALVAAGFTYDGVAELLGARAHDALARNETSPGLARTRGGSPLETLVRLFLLQTTVTLEDAERALPGLVDRLAVDGLVARSVGEVAARLDCRPYAASHGTGDDDVDLWVVSDLTPGLDGGPHRVGTDHVLGISPASTSLAQLTLREEVGSALDLGTGCGVQALHLARHSGRVVATDVNARALAVTRFNAALNGVDVDVRDGSFFEPVRGERFDLIATNPPFVISPATGERLVYRDSGLPGDRVVEDIVRTAPRHLNPGGWCQVLANWVIQRDRPWDERLAGWLPEGHDALVVQREVLDPASYVELWLKDAGLHGSPDYLSRYDTWLSWFDDQGIEAVGFGWINLHEAGTSDGRTELLSWPYDVEQPIAEAIGAWGDAVRADVGLDDHLQLRPDVVQETHGPVGAEDPETIVLRQQVGFRRARTVDTVEAALAGTCDGDLSVGQILDALAVLLDLDAAEVRTSYLPAVQDLVRQSFLTR
>NZ_CP040695.2|WP_137295004.1|412971_415281_+|sodium-translocating-pyrophosphatase
MAGFHPAAVEVSGGNLVLVIVVALIALGALAMAYLFRSEVLAAGEGTANMKNIAQAVQEGADAYLQRQFRTLAIFAGVAFFVLLALPADDLTVRIFRSVFFIVGAVFSAAVGYLGMSLAVRANLRVAAAANEPGGREPAMRIGLRTGAMVGMLTVGLGLLGASLVVLFFQDEAPDVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQNIPEDDPRNAATIADNVGDNVGDCAGMAADLFESYAVTLVAALILGSQAFGDKGLVYPLLIPAIGALTAVAGVYLTKPKVGEPGLTTINRSFYLSAGIAALASVVLSFVYLPTSFADFEGLAGSNTLELISGQPEGNPALIASVAVVIGIVMAAGILALTGYYTGTEYKPVKDVGRTSLTGAATVILSGLSVGFESAVYTTLVIGAAVFGAFLLGGASLTISLFAVALAGCGLLTTVGVIVAMDTFGPVSDNAQGVAEMSGDVSPEGAQILTELDAVGNTTKAITKGIAIATAVLAATALFGSYATSSIEALDEAGALDELTGFFVFDPSVLVGVLLGSAVVFLFSGLAINAVARAAAAVVYEVRRQFREIPGIMEGTGRPEYGKVVDIVTRDSLRELITPGILAVFAPVAVGFGLGVTALAGFLAGAIGTGTLMAVFLANAGGAWDNAKKLVEDGNHGGKGSPAHEATIIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIASAVVSTSVGEDENDVLRILIALVSVAIIAGAVYVSKQRESNLGDDVPLADKPV
>NZ_CP040695.2|WP_137295005.1|412420_412759_+|STAS-domain-containing-protein
MDLSLETRDVGGRTIVAVGGEIDVYTAPKLRDRITELVAAGTYDLVIDMEAVEFLDSTGLGVLVGGLKKVRAHDGSLSLICNQDRLLKIFRITGLAKVFVIHESADAALAGA
>NZ_CP040695.2|WP_148240952.1|409831_412171_-|DEAD/DEAH-box-helicase
MAGLLDRLAAVPGREGRLTHVEVRPSRAARHADWPAWAAPSVVAGLTARGVARPWAHQVEAAEAAWAGRHVVLSTGTASGKSLGYQLPALSAALAGRGERRGRGAGTLYLAPTKALAHDQLESLLALRLDARITTCDGDSSHDERDWARAHAEYVLTNPDMLHRSILPGHQRWASFLGSLRYVVVDECHHYRGVFGAHVAHVLRRLRRVCASYGASPTFVLASATTAEPALTAARLTGLDVEAVTDDGSPRGEVTLGLWEPPLTSYVGENGAPVRRAATSETADLLADLVAEDVHTLAFVRSRRGVEQVALTAAGLLEEVDPALATRVAAYRGGYLPEERRALEGALRRGELVGLAATNALELGIDVSGLDAVLIAGFPGTRAALWQQVGRAGRDAQDALGILVARDDPLDTYLVHHPDALLGRPVEAHVFDPGNPYVLGPHLCAAAQEIPLTEADLPIFGPTAREVVDALVERGLLRRRPRGWFWTDRRRAADLADIRGAGGSPVTLVEDVTGRVVGTVDAGRAHGTAHTGAVYLHRGETWLVDELDLESRVATLERADPGYTTSARDVTDIAIVEEREHRSWGRCRLSFGAVEVSQQVVSYLKRRQPHGDVIGEVPLDLPATSLTTTAVWWTVPDDVLAAAGLLEADLPGSAHAAEHCAIGLLPLVATCDRWDIGGVSTARHADTGELTVFVHDGQPGGAGFSERGFHAARRWLTATREAIASCSCELGCPSCVQSPKCGNQNNPLDKTGAVALLDVLLSGAEDDAGENGPDAGGRA
>NZ_CP040695.2|WP_137295006.1|409510_409822_-|hypothetical-protein
MLILGLVVILVGAVLVVGGLFTTEVSGGDVEILGIGLSPSALFVVGLVAGLCILVGLWLTKWGTQRGLRQRKEQKKIDELSQKLDRAEAGRRRDLDDDPDYRA
>NZ_CP040695.2|WP_137295007.1|409139_409523_+|hypothetical-protein
MSRGRGRAAGRDGGEERGGATVVTLALAGVLLLLGAALGVVAALVVGHRTAQAAADLAALAAAQALARGSDGCGAAATVAAANGAALTGCAVEGREVRVEVGVTGPRWLGQSGDLTARARAGPAQAR
>NZ_CP040695.2|WP_137295008.1|408735_409143_+|pilus-assembly-protein
MRSTRAARAAVSHHAPRGRRGQRGAVTAELAMALPLLVALTIGLVWLLSVGAAQVRAVDAARETARAVARGDDEAAAVAAGQRVVPDGGRVTVRGAGDSVVAEATARVEGPGGLFDFLPAVTVRAEATALVEESG
>NZ_CP040695.2|WP_148240300.1|408514_408739_+|DUF4244-domain-containing-protein
MTRTTRTTRPSRTNRPSRTSRRRRDDGITTAEYAVGTAAGAGLAGLLYKLLSGGFGDRLLKTLFDHVLGLLGIG
>NZ_CP040695.2|WP_148240303.1|419542_422299_+|type-I-DNA-topoisomerase
MAHKLVIVESPAKARTIGGYLGDGYVVESSIGHIRDLPNNAADTPAKIKDKSWGRLAVDVEDGFTPYYVVPRDKKSHISKLKGLLKDADELFLATDEDREGEAIAWHLLDELKPKKDVTVKRMVFHEITKQAILDAAANPRDIAMDLVEAQETRRILDRLYGYEVSPVLWKKVMSGLSAGRVQSVATRLVVDRERQRMAFRAASYWDLEGTFDAGSKHDQRMFPARVHSLDGTRVASGSNFGQDGLLKAGADVVHLDRARAQSLVSALADTTYDVRSVESKPYRRSPYAPFRTTTLQQEASRKLGMSASVTMSVAQRLYENGFITYMRTDSTTLSGGAVEAARSQVRELYGAEYVPDVPRTYTSKVKNAQEAHEAIRPAGESFRTPAQTGLTGDQFRLYELIWMRTVASQMKDAVGQSVSVRIGGAAATGEDVVFSASGRVITFHGFLKAYVEGTDDGGAKDDQETRLPALVEGDAVSAASLSANGHETKPPSRFTEATLIKELEEREIGRPSTYASIIGTILNRGYVYKKGTALVPAWLAFSVIRLMEDHFPRQVSYEFTAAMETVLDEIARGEKDRVTELGEFYYGSDSVQGLHTLVTELGDIDARENATFPVGDADSGIFLRVGKYGPYLEGPDDDGNPLGRRANVPDDLPPDELTLDKAKELLANPAGEEIALGRHPVTGLEVVAKNGRYGPYVTELLPEDAKKSDKPRTGSLFKSMSLDTVTLDDAVKLLSLPRVVGVAPPAEGAEGEAAEGEEITAQNGRYGPYLKKGTDSRSLTSEEQLFTVTLDEALAIYAQPKQRGRAAAAPPLKELGNDPVSGQPVVVKSGRFGEYVTDGEYNATLRKDDSVDAITLERAAELLADRRERGPAKGAKKGAKKAPAKKSTAKKTAAKKTTTTKAAAKKTTAKKTTAKKA
>NZ_CP040695.2|WP_148240953.1|422309_422960_+|dTMP-kinase
MPASRPVYADHGVFVCFEGGEGSGKSTQSRRLATWLRAAGHDVLLTFEPGDTPVGADLRRIVLSPETGALGDRTEVLLYAADKAEHVETVVRPALARGGVVITDRYVDSTLAYQGAGRALDVAEVEAVARWATGDLRPHLTVVLDLEPEAGLARFEGRDRIEAESLEFHQRVRAAFPRMAAADPDHYLVLDARADVDEIEAAVRAAVTPLLPPRAT
>NZ_CP040695.2|WP_137295013.1|423066_424200_+|DNA-polymerase-III-subunit-delta'
MWAGLVGQDRAVGVLRPAVAGHGMTHSWLFTGPPGSGRSNLAVAFAAALQCEQGGCGECHACRTALAGTHADVDVVRTQKLSIGIDEVRDLVRRSALAPAGRRWQVIIVEDADRLTEPAANALLKTIEEPNGRTVWMLCAPTVEDVLPTIRSRCRQLTLATPSPAAVAAHLVRHDGVSEALASYAARASQGHIGRARALALDEATRERRRTVVSYPTSLTSLGACMRAATELAAVAKEEADAITGDLDAREKADLDVQYGVVERGRRPREYSPALSALDKSQKTRAKRRVIDVVDRGLMDLVSVYRDAVALALGAPGELVNAEIRADVEEVVRTSTPELNLRRIGWIFEARQQMVEFNVPVALALESMMVALKVPSS
>NZ_CP040695.2|WP_148240304.1|424213_425788_+|alpha/beta-fold-hydrolase
MNKQVVWVVAVIAVLVLGVGSGLTAALLVGDGGDGSSDGGGERDRGAAPETSSLGPAGAVPAGLEEFYGQQLAWEGCGSNQCATLTVPLAYAEPGGETIGIALERTLARDPDNRVGSLVVNPGGPGAPGTTMAENADGYFTASLLERVDVVAFDPRGTGDSAPVDCLSDADLDAFVAQDPTPDDAAERQEFAASEEEFFAGCVAGSDGVAAHVSTVEAARDMDVLRSVLGEEQLSYLGFSYGTTLGSTYAELFPGNVGRFVLDGATDPTLDFRDNALSQAAGFQTALDAYLDDCVAGEGCFLGASREEAQGTISDLFASIEEQPLPTSGDRDLQIGNAFYGVAYPLYSRESWFLLDQGLQEALDGDGTTLLALSDLYGSRNASGGYDDNSLEAFYAINCLDDPTSASAEEIPAEYPAFDAASPTFGRFFAWGLAGCLGIQDEAAEPTPTIRAAGAAPIVVVGTTRDPATPYEEAVALAEQLESGVLLTRDGDGHTGYNKGNSCIDDAVEGYLLDGDVPADDTRC
>NZ_CP040695.2|WP_148240305.1|425841_426453_+|hypothetical-protein
MRTLVRTVALLASTLSLLVVAPAPPSTAAGGGTPPAGLRAAACAAGRPQVGVGDTTDRGYHGFDITAMGLWNNPGDACVWTTVAGRFTSAKAQALQVLIDTDGRGGPEFYTFGYSPRDGDDRTGSFLVGRRDGEWTYLDCEVRTFWRPRKDQLGIGVPQWCLGDPRSVRVKVQVWDIREYRPNNTWRGRADQAPNRRWSPAAG
>NZ_CP040695.2|WP_138874941.1|426460_427447_-|VWA-domain-containing-protein
MRIPAPAPLFALASPGWLWLLVPVVLLAVFYGVQQARRSRYAVRFATLPMLERLVPRQPAWRRHVPAALLLLAFVGLAVAASRPQVDEQVPRERATVIVTVDVSLSMEATDVDPNRLTAARAAATAFVEGLPDGFNVGVVAFAGSATVLAQASPDHEAAIEALGRLELDRGTAIGDGVLTSLAQIEAIGDSAGTDADGEPVPAHVVLLSDGTNTVGSTVEMAVGAAQEAGVPVSTIAYGTPEGTVTVDGQLVPVPVDQPSLDALAEATGGTGYAAETADELDEVYDDIQSSIGFRTEPRDVTPFFVAGSLLVALLAAAFSLRWFARLP
>NZ_CP040695.2|WP_138877025.1|427443_428373_-|DUF58-domain-containing-protein
MPLGTASPEAVFDALDLAVRRRLPGRLHGDKRGLRLGPGSDPEEVVRYRPGEDDVRRIDWNVTARSGEAHVWRPVAEHELEAWVLVDDTASMAFGTVHLEKRQVADGVTAAVALLTQGPGNRLGTAHLAADGLTWAQPLPSRAAAHRALRRHRATAAVGSGGSVDVGLARAVRTFATRHPRPGVRVVVTDFVEPDGRMERPFAWETPLRRLAAVHETLVVEVVDPRELELPDVGAVTLEDPETGRRREIFTSDRRLRARYAAATAAHRAATADAVRAARAGHVLLRTDRDWVRDLARFVNGRPMRRVTA
>NZ_CP040695.2|WP_138874942.1|428390_429437_-|AAA-domain-containing-protein
MSAEQEREVADASATLERALIEVKKVVVGQDAMVERMIIGLLARGHILLEGVPGVAKTLAVRTLADVVGGSFARLQFTPDLMPGDITGTRVWRASSETFDVELGPVFANLVLADEINRAPAKVQSALLEAMAEKQVSIAGTSHRLPDPFLVLATQNPVESEGVYRLPEAQRDRFLLKVDVPYPSGQEEFTILHRMSVKPPRAEAVLDPVEVIRLQGVADGLFVHHSVASYLVNLTIATRSPERYGLAHLREVIELGVSPRASLGMLAAGRALALLRGRSYVLPADIAEVASDVMSHRMLLSFDAVADGADPRAIVREVVAAVPQPTVASREDPDAGHTAALAAQGQSS
>NZ_CP040695.2|WP_137294993.1|429501_430425_-|LysR-family-transcriptional-regulator
MLSLHQLRCFLATYEHGSLTAAADELGYAQPSVSEQVRALEKSLGVQLFRRVGRGVVPTTVADTLRPHAEKVLASVAEAQDAVRSVRSFETGTIRFGMFGVARLYASAGLIADVLARYPGVRVELVGQNSTAVAEDLRRGRLEAAMLAVAGVRSEGITITPVAREELVYISADPARLATPVTAHRLALATLVMPETTWRAEDSTRILLRQLLHETGRNPQTRIEVEDVETAVEIVGLGLADSVIPRGAAEQLLPRLAPNAGWVALRPRVWDTFAVVHRAGAVLSPAAQLMIELATARIREIAEPLGR
>NZ_CP040695.2|WP_137294992.1|430511_430694_+|hypothetical-protein
MFVHSCTSCGKRQLTFPSQLSGVTHTDEGMVVSFTCWCGATQTLDHSPFDGGRARDLVDA

Crispr_ID: NZ_CP040695_5

• CRISPR_ID: NZ_CP040695_5
• CRISPR_location: 739274-739387
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_5

Consensus_repeat	Method
GACCCGTCGCTGATCACTGACGGGTCAG	CRISPRCasFinder

spacers of NZ_CP040695_5

>5.1|739302|58|NZ_CP040695|CRISPRCasFinder
AGCCACACCTGAGGTGACCCGTCGCTGATCACTGACGGGTCAGCGCCACACCTGGGGT

CRISPR arrays and Neighbor proteins around NZ_CP040695_5

CRISPR arrays

The CRISPR arrays of NZ_CP040695_5

>merge|NZ_CP040695|5|739274-739387|CRISPRCasFinder
GACCCGTCGCTGATCACTGACGGGTCAGAGCCACACCTGAGGTGACCCGTCGCTGATCACTGACGGGTCAGCGCCACACCTGGGGTGACCCGTCGCTGATCACTGACGGGTCAG

>NZ_CP040695|5|5|739274-739387|CRISPRCasFinder
GACCCGTCGCTGATCACTGACGGGTCAG	AGCCACACCTGAGGTGACCCGTCGCTGATCACTGACGGGTCAGCGCCACACCTGGGGT
GACCCGTCGCTGATCACTGACGGGTCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138875093.1|740106_740979_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl|CDD|235695
NZ_CP040695.2|WP_138875094.1|741073_742063_+|AMP-binding-protein	unknown	unknown	gnl|CDD|236108
NZ_CP040695.2|WP_148240353.1|736673_738296_+|cytochrome-c-biogenesis-protein-ResB	unknown	unknown	gnl|CDD|377471
NZ_CP040695.2|WP_137292314.1|725854_726526_+|redox-sensing-transcriptional-repressor-Rex	unknown	unknown	gnl|CDD|235486
NZ_CP040695.2|WP_138875098.1|748106_748940_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|187578
NZ_CP040695.2|WP_137292577.1|727930_728935_+|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP040695.2|WP_137292316.1|728931_730620_+|bifunctional-uroporphyrinogen-III-C-methyltransferase/uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|223086
NZ_CP040695.2|WP_137292328.1|745885_747778_+|Na+/H+-antiporter	unknown	unknown	gnl|CDD|223104
NZ_CP040695.2|WP_137292315.1|726536_727916_+|glutamyl-tRNA-reductase	unknown	unknown	gnl|CDD|234592
NZ_CP040695.2|WP_138877044.1|742080_743031_+|o-succinylbenzoate-synthase	unknown	unknown	gnl|CDD|235084
NZ_CP040695.2|WP_138875087.1|730766_731774_+|porphobilinogen-synthase	unknown	unknown	gnl|CDD|236450
NZ_CP040695.2|WP_137292323.1|739655_739919_+|DUF4229-domain-containing-protein	unknown	unknown	gnl|CDD|379415
NZ_CP040695.2|WP_137292579.1|739390_739588_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240356.1|749058_749664_+|hypothetical-protein	unknown	unknown	gnl|CDD|226851
NZ_CP040695.2|WP_148240355.1|744660_745824_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP040695.2|WP_137292318.1|734670_735348_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP040695.2|WP_138875095.1|743027_744626_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl|CDD|236020
NZ_CP040695.2|WP_137292320.1|735906_736674_+|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl|CDD|280792
NZ_CP040695.2|WP_138875089.1|735347_735914_+|redoxin-family-protein	unknown	unknown	gnl|CDD|239264
NZ_CP040695.2|WP_138877043.1|733367_734648_+|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl|CDD|234607

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138875093.1|740106_740979_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl|CDD|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	1.4978e-112
NZ_CP040695.2|WP_148240353.1|736673_738296_+|cytochrome-c-biogenesis-protein-ResB	gnl|CDD|377471	pfam05140, ResB, ResB-like family. This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.	9.39979e-155
NZ_CP040695.2|WP_137292314.1|725854_726526_+|redox-sensing-transcriptional-repressor-Rex	gnl|CDD|235486	PRK05472, PRK05472, redox-sensing transcriptional repressor Rex; Provisional.	1.31051e-111
NZ_CP040695.2|WP_138875098.1|748106_748940_-|NAD(P)H-binding-protein	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.43629e-79
NZ_CP040695.2|WP_137292577.1|727930_728935_+|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.4442e-133
NZ_CP040695.2|WP_137292316.1|728931_730620_+|bifunctional-uroporphyrinogen-III-C-methyltransferase/uroporphyrinogen-III-synthase	gnl|CDD|223086	COG0007, CysG, Uroporphyrinogen-III methylase [Coenzyme metabolism].	3.68992e-61
NZ_CP040695.2|WP_137292328.1|745885_747778_+|Na+/H+-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	4.42276e-79
NZ_CP040695.2|WP_137292315.1|726536_727916_+|glutamyl-tRNA-reductase	gnl|CDD|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	8.22784e-147
NZ_CP040695.2|WP_138877044.1|742080_743031_+|o-succinylbenzoate-synthase	gnl|CDD|235084	PRK02901, PRK02901, O-succinylbenzoate synthase; Provisional.	3.32251e-145
NZ_CP040695.2|WP_138875087.1|730766_731774_+|porphobilinogen-synthase	gnl|CDD|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP040695.2|WP_137292323.1|739655_739919_+|DUF4229-domain-containing-protein	gnl|CDD|379415	pfam14012, DUF4229, Protein of unknown function (DUF4229). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 95 and 122 amino acids in length.	1.10714e-08
NZ_CP040695.2|WP_137292318.1|734670_735348_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	9.59234e-43
NZ_CP040695.2|WP_148240356.1|749058_749664_+|hypothetical-protein	gnl|CDD|226851	COG4430, COG4430, Uncharacterized protein conserved in bacteria [Function unknown].	2.76042e-25
NZ_CP040695.2|WP_148240355.1|744660_745824_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.00310285
NZ_CP040695.2|WP_138875094.1|741073_742063_+|AMP-binding-protein	gnl|CDD|236108	PRK07824, PRK07824, o-succinylbenzoate--CoA ligase.	7.26671e-73
NZ_CP040695.2|WP_138875095.1|743027_744626_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl|CDD|236020	PRK07449, PRK07449, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Validated.	1.89688e-141
NZ_CP040695.2|WP_137292320.1|735906_736674_+|cytochrome-c-biogenesis-protein-CcdA	gnl|CDD|280792	pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region. This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family.	4.59984e-41
NZ_CP040695.2|WP_138875089.1|735347_735914_+|redoxin-family-protein	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	5.65628e-33
NZ_CP040695.2|WP_138877043.1|733367_734648_+|glutamate-1-semialdehyde-2,1-aminomutase	gnl|CDD|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0

Protein sequences

>NZ_CP040695.2|WP_148240353.1|736673_738296_+|cytochrome-c-biogenesis-protein-ResB
MSDLRQHSDLPTRRPGELGARELARWAWRQLTSMRTALVLLLLLALAAVPGSVIPQSGVDALEVSQWKEAHPNLTPVYERLGLFSVYDSAWFSAIYLLLMISLVGCIIPRTLVYARALRAQPPAVPRNLSRLPDHTAYETDDDVEVVLERARTALRRKRYRLRVADDGPAGVSAEKGYLREFGNLVFHISVIVVLVGFAVGSLRGYQGGVIVLAGNPSSGLEGGTFSNTPASYDDLDPGSLFGADDFDPFTFTVDDFDITWLTEGSAAGTAREFRAPITYREGLDGAEQTYDLRVNHPLSIGDTDVFLIGHGYAPVITVRDGDGEVAYQGPTVFLPQDPSFLSFGVVKAPSARPGAIGLEGVLYPSFEFIDGNPVTVFPALANPLISMNVWTGDLGLDDGVPQSVYVLDTSGATPVDDADGTQLRLDLQLGETVQLPDGLGSVSFDDVQPWVRVQISQSPGKEVALGGVVLALLGLLGSLFIRPRRVWVTARRREGEESDRRGATMVEVGLLDRSGGADLTDVLDEIVAALQGRAEEEKA
>NZ_CP040695.2|WP_137292320.1|735906_736674_+|cytochrome-c-biogenesis-protein-CcdA
MGDWFQDQAAAGSLALALPVAMIAGLVSFFSPCVIPLLPGYLSYATGISGADLAAGEASNRRGRMLLGSVLFVLGFTVVFVLIGTALGGIGVSVRQYEDQIRIGMGIVLVVLGLVFAGAVPWLQREWRIHRVPAVGLGAAPLLGALFAFGWAPCIGPTFGVILTLTYSTDGATAARGGVLSAAYALGLGIPFIVVGLFYARSLRALSWVRKHQRAVMQIGGAMLVVIGVLFLTGWWEWAVQWVQVRLVGGFQVPV
>NZ_CP040695.2|WP_138875089.1|735347_735914_+|redoxin-family-protein
MRVRRFVAAALLTPTLALVAGCSGGLDGTGDANFVYGDGAITLVPPEDRGDTVDIAGETLGGEQLDLADLRGRVVVLNVWGSWCNPCREEAPVLKTASEEVDAAFVGLSFRENSFENARSFEREFGIGYPTIADTGAGVLQLGRWAPTSPPTTYVLDEQGRVAALITGAVTSATTLEDLVEDVANADG
>NZ_CP040695.2|WP_137292318.1|734670_735348_+|histidine-phosphatase-family-protein
MSTPDTIVHLLRHGEVHNPEGVLYGRRDGFHLSDLGNRMAQKVADTIKDRDIVHLVSSPLERAQETAAPLALARGLTPVLDERVLESTNKFEGMTFGKGRNSLKNPSTWRHLWNPFKPSWGEPYDQVVARMMAAVRDAREAAAGHEAVVVSHQLPIWITRLAAEKRSYLHHPKNRQCTLCSLTSLHFVGDRLTQVAYSEPAGDLIPVGDKGAPFSAGNAPEEKRP
>NZ_CP040695.2|WP_138877043.1|733367_734648_+|glutamate-1-semialdehyde-2,1-aminomutase
MFDRARAVIPGGVSSPVRAFNAVGGTPRFIRSAAGPRLTDVDGNTYVDLVCSWGPMLVGHAHPEVQEAVLAAVARGTSYGAPTEPEVELGEEILARTPVERVRFVSSGTEATMSAIRLARGFTGREVVVKFAGCYHGHVDALLASAGSGLITFAVPGTPGVPVSSTELTLVLPYNDRAAVTAAFAEHGDRIACVITEAAPGNMGVVPPEPGFNQFLSETCTRHGALFVSDEVMTGFRASRRGQWGLDGAVEGWAPDLMTFGKVMGGGFPAAAFGGRADVMSMLAPEGPVYQAGTLSGNPVATTAGLATLRLATDEVYARLTAAGDTIKAATAEALSAAGVAHTIQSVGTMFSVFLCEGPVRDFTEASRTDVAAYAALFHAMLDAGVYLPPSAYEAWFLSSAHDDAAVQTILDALPGAARAAARTQK
>NZ_CP040695.2|WP_138875087.1|730766_731774_+|porphobilinogen-synthase
MTDAAPHVRRPTIRPRRLRTTPALRRAVAETSLEARQLVLPVFVREGLTEPRPISSMPGVVQHSTDSLRRAAAEAADLGLAGIMLFGIPEHKDAVGSGAVDPDGVLNRAIVDVVAEVGDALPVMADLCLDEFTDHGHCGVLTADGRVDNDATLEVYAEMARAQAAAGVDLVGPSGMMDGQVAVVRDALDGAGHTDVAVLAYSAKYASAFFGPFREAVDSSLRGDRRTYQQDPANGREGVREALLDIAEGADIVMVKPALAYLDVLRRVRDAVDVPVAAYNISGEYSMVEAAAAHGWIDREAAILETLVSIRRAGADIVLTYWASEAARLLRTRTR
>NZ_CP040695.2|WP_137292316.1|728931_730620_+|bifunctional-uroporphyrinogen-III-C-methyltransferase/uroporphyrinogen-III-synthase
MTRAKSPSVADLIARSWVSFVGSGPGDPDLLTVRAVDLIRQADVVVTETPEHAGLVRTLLGLPTPVEPADVDDPAAVEPVGPVGPELVDGGFGEDGQPLTHANRAKVVVKQAKRGLRVVRLLSGEPFLYASGPEEAQACAKAGIGFEVVPGVSSVSAVPAYAGIPLTTKDHRELAVVTCGDKVDWSRYGDNRTLVLLSAVGQIADVAKALVAAGRSPQTPVAMTRVGTTTEQQTVASTLEHIAADARAARMSPPAITVVGDVVDLRETLSWFETKPLFGWRVLVPRTKDQAASLSTGLRGYGAVPEEVPTISVEPPRNPLQMDKAVRGLVEGRYEWIAFTSVNAVRAVREKFEEYGLDARAFSGLKIAAVGDKTAAAIAAWGLRADLVPSGEQSAAGLLADWPEYDEVLDPINRVFLPRADIATETLVAGLVDLGWECDDVTAYRTVRATPPPAPVRDAIKSGRFDAVVFTSSSTVRNLVGIAGKPHPSTVIAVIGPATAKTAEEHGLRVDVLAPKPDVDELVRALADFGGARRSAMVEAGEPVTKPSDRKPSARRSSRAKA
>NZ_CP040695.2|WP_137292577.1|727930_728935_+|hydroxymethylbilane-synthase
MRVGTRRSLLATTQAGHVADLIRERLGHEVELVEITTEGDRSQASGTPLVGSSVTGVFVGALREALVDGRVDVAVHSLKDLPTQPAPGIALAAIPVREDPRDAVVARDGLTLGELPAGSRVGTGSPRRAAQLHALGLGLDVVGVRGNVDTRIGKVLDGELDGVVLARAGLARIERLADVTEVLDPLQMLPAPGQGALAVECRDGDPLALELARLDDPASRAAVEAERALLATLEGGCSAPIGALALVVEGDDGDELWVRAVALSPDGSLSVRKSASGDPADAAGVGNRLASEMLADGAGQLNPSAARPATADGGAAAQRPPSSQENPVAEVQNP
>NZ_CP040695.2|WP_137292315.1|726536_727916_+|glutamyl-tRNA-reductase
MSILVVGISHNSAPVSVLERVALDADGVHKLVTDVASCAHVTEATVVSTCNRVEVYADVDRFHGSVESLSRLLVERAGETAEAMLQHLYVHYDDGAVAHLFQVAAGLDSMAVGEGQILGQTRAALRLGQELGTVGPALNSLFQQALRVGKRTRAETGIDRVAPSLVSAALDRAELAVGPVAGRAVVVVGAGAMAGLATATVSRLGAARVSVVNRSADRAQRLALEHAAVPVALADLPAALAGADVVITCTGATGILVTRDMVDRVRDADSAPLAVIDLALPHDVEPSVADLDGVSLIGLAELAESLADSDAGREVVEVRRVVGEEVDAFLTARRQSSVTPTVVALRSMATAVVDAEMSRLEARLPRLDDASRAEIRHTVRRVADKLLHEPTVRVRELANEQGAVSYERALAELFALDPEAVVAVTRPDVTATGRPSSAPATRSSDEQRRGDADATGGTP
>NZ_CP040695.2|WP_137292314.1|725854_726526_+|redox-sensing-transcriptional-repressor-Rex
MTARTPSRTLGESVRDIPEATVARLPVYLRALNTLAEADTRTCSSEELATAAGVNSAKLRKDLSYLGSYGTRGVGYDVDYLRYQIAREIGVTQDWPVVIVGIGNLGHALANYSGFRSRGFRVVALLDADDTRHGEVVAGVDVRAFDDLEEIVTTHGVAIGVIAAPAAAAQDVADRMVACGITSILNFAPSVISVPDGVDVRKVDLSIELQILAYHEQRKAQLS
>NZ_CP040695.2|WP_137292579.1|739390_739588_-|hypothetical-protein
MFLLILFAVAIYLLVRVFQERGMLPDRPARPRRPGPRRIVAPDDDEDFLRDLDRKRREPEDPETT
>NZ_CP040695.2|WP_137292323.1|739655_739919_+|DUF4229-domain-containing-protein
MKDFVVYTALRIGLFLLTWAAVTGAWLLVAGEAALGLTFLIAFVLSGIGSYFVLSGPRDRLARHVEQRAGRISEKMEERAAKEDVPD
>NZ_CP040695.2|WP_138875093.1|740106_740979_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MATAAEWVQGARPRTLPAAVSPVLAGTGVASYDGGAVWWKALLALLVSLALQVAVNYANDYSDGIRGTDDVRVGPMRLVGSGVATPGAVKRAAFLAFGVAGAAGLVLAATTAWWLVAVGLVSVVAAWYYTGGSTPYGYLGLGEVMVFVFFGLVAVVGTTYVQTEAWSWAALAAACGIGALACAILVVNNLRDIPTDTDAGKRTLAVRLGDAATRRLYVGLVAAAAVAVVAVAALTSWWALLGLGFLAVAGRGVRTVLGGATGPRLIPVLQSTGIGELAWAALVAVPLLLT
>NZ_CP040695.2|WP_138875094.1|741073_742063_+|AMP-binding-protein
MDVPRLRAWLAAPGEPEPLVVETSGSSGTPKRVVLSRRAVLASVAASADRLGGTGPWALRLPLGYVAGLQVVCRSLVAGHEPLTDPTRWPDGEGWFTSLVPTQLHRILEDADPTDRSALARAHTVLLGGGPVDPALRAGAAAAGVRVVATYGAAETAGGCVYDGVPLDGVAVDVDVSGRIRLGGPTLFDRYDGDPDLTAQTLVDGWFLTADAGRLGPDGRLEVLGRVDDVVVSGGVNVPGPAVAARLRAHPGVAAAEVLGVPDEEWGNRLVAFVALADAARDVDATALRAWVAAAHPRAWAPRQVVVLDAIPLLANGKADRLRLRELAR
>NZ_CP040695.2|WP_138877044.1|742080_743031_+|o-succinylbenzoate-synthase
MRVLSIPMRTRFRGITVREVALVEGAGGWGEWSPFLEYDAATAWPWLACAREAAAGDWPAPLRSEVAVNVTVPAVDPERAHRIVLDGGCRTAKVKVAEPGQSLADDEERVAAVRAALGPGGAVRVDANGGWSVEAAVTAIRRLDAAAGGLEYAEQPVATVEDLALVRRRVDVPIAADESIRRAADPYRVRDLEAADIAVLKVQPLGGVRACLRIAEDIGLPVVVSSALETSVGIAAGLALAAALPELPHACGLATVQLLTDDVAVTPLLPVDGVLPVPVAGAPLVDLAALDRLAAPPDRVAHWTARLAAVTRGGRP
>NZ_CP040695.2|WP_138875095.1|743027_744626_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MTASATELARDVVRQLLDAGISEVVIAPGSRNAPLSFAFFDAARDGLVRLHTRIDERTAGFLALGLTRSHARAAVVCTSGTAVANLHPAVLEAVHAGVPVVVVTADRPARMRGTDANQTTDQVGVFGPLVPTVDLASPQPLELEGHGPVHLNVQLDDPLLPGSRWEAAADGAGADRTSRSWSDPPPVELPLGPRTVVVAGDDAGPPARRLAEAAGWPLLAEPSSGSRTGENALRCYRLLLGEGGDLAGRVERAVVHGSPTLSRPVQWLLARADVEVLSVPGRGAWAERPYPVAGTAAAYAVAGPDDPAWLQEWRDADRDVARRLDALLAGRPGLTPYEVAGAVHRALGPGMQLVVGASSPIRDLDVMARPTGVGERRKVIANRGLAGIDGTISTAVGAALGRRHGSTIALMGDVTFLHDSNGLVLGPTEPRPDLVVVVVNDDGGAIFTTLEQGAPEHADRFEALFGTPHHVDLAALCAATRTPHLEVGSLPELEQALASPNGGIEVVEVRVRRDDRRELDLAIRSLAAASPH
>NZ_CP040695.2|WP_148240355.1|744660_745824_+|hypothetical-protein
MELHDRLYALGLQSGRHVFDDPAAFRGVLDDAVRRGEVSRDDVDLLADAIRSGALGAMLAAMDAGTDALPAAGEAGARVVGGRRSKTPPGPAEVARGQWACAVLGFAVGRVSESDVVRFRTLAQASPGSGTGSGGASAPTYAPGYPGQPYQPTYQPAYQQAQGYPGGPVSWTPAPGRRSRTGLYVGIGVTAAAVVIAVVLALVLTGGDDEDPVASDTGSSGAPSSEVTSDPTSDPTSDPTSPATSDPTSDPTSPATSAAPSGRVSDEAAAGYTLALQTFSTDFGKASDELSSATTDDDLAGALAGSAGMRAAVYDLDLAVRGLDLTPIQPTVNEFLGVSGEMITGFDETASSATSSLDVNLGFLGLPTIEYTAAFQAVAEEIDKSRR
>NZ_CP040695.2|WP_137292328.1|745885_747778_+|Na+/H+-antiporter
MEIALLLVSLAVSVLAVTAVADRIDIPAPLVLIVAGVAVSYVPGVLEVRLEADVVLFGLLPPLLYATAIQTSLVDFRANLRTILLLSVGLVVFTAAGIAVLLHALLPGLGWGLAFAIGAVVAPPDAVAATAVGRRIGLPRRITTILEGESLLNDATALVSLRTALAAGGLAAHGHGGGHVEEVTAQGVALDFVVAAGGGVLVGLLAFLVVAFLRRKLTDPLMDTALSLIVPYAAYVGAEEISASGVIAVVVAGLLLGHRAPILQTAQSRIAERTNWRTIAFVLENVVFLLIGLQAASLIEAVEESDLSGTRVALACGLSLVGVIVLRLAWVFPARYLLARNVGDHEARAVPPASYTFLLGWAGMRGVVTLAAAFVIPAEAEYREVLLLVAFTVVAGTLLVQGLSLPFLARRLDVPPPDPMDDALARATLLQQASKAGFKKLKSLDEDDLHGVVSLIKQRIEQRNFAAWERLGTTADEETPSELYGRLRLTMIEEERRRVLAIRSEGTTPSVVVAEVLAMLDVEESMLDRATQARAELRTSAVRRPGEECDHLAEHPVVETVSDGTCPACVANGNRWVALRQCLDCGHVGCCDSSPDRHATTHFQETGHTVMQSAEDGEEWRWCYVHHMTA
>NZ_CP040695.2|WP_138875098.1|748106_748940_-|NAD(P)H-binding-protein
MLALTGSTGALGGPVAHALADLRPRLLVRDPARAPQLGEQSGGVHVTPYDDAAAATAALEGVDLLFMVSAAESEHRRREHRTFVEAAARAGVRHVVYTSFSGAAADATFTLGRDHHDTEVAIRESGMDFTILRDAFYADVLPLFADASGAIRGPAGHGSVAAVARADVADAAVAVLRDPRAHLGATYTLTGPEALTLDEVADRAGAVLGRPLRYEPESVEEAYAARRAAYPDAGEWQLDAWVSTYVAIADGSCAAVTDDVRRLTGHPARTLEQALAG
>NZ_CP040695.2|WP_148240356.1|749058_749664_+|hypothetical-protein
MTAPVPAPEEGEAHDGRPYVHPETLEQWRAWLAAHHARGSGVWVYQWRRATGRPALGYEEQVVEALAWGWIDSTAGTVDEQRARMWFAPRRPTSGWSRPNKQRVERLHAEGRMQPAGRAALDLAHANGSWTLLDDVEDLVVPPDLAAALAAHPGARAHWDSFPPSTRKQMLTQVVTAKKPETRTARIARFADAAARGERGA

Crispr_ID: NZ_CP040695_6

• CRISPR_ID: NZ_CP040695_6
• CRISPR_location: 906186-906308
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_6

Consensus_repeat	Method
CCCTGCCCGTGCAATTGCCGCGAATGGCTCGG	CRISPRCasFinder

spacers of NZ_CP040695_6

>6.1|906218|59|NZ_CP040695|CRISPRCasFinder
TTCCGACGTCCGAACCTGAGCCGATCGCGGCAATTGCGCGCCCTTGGCCGCCCTGCCCA

CRISPR arrays and Neighbor proteins around NZ_CP040695_6

CRISPR arrays

The CRISPR arrays of NZ_CP040695_6

>merge|NZ_CP040695|6|906186-906308|CRISPRCasFinder
CCCTGCCCGTGCAATTGCCGCGAATGGCTCGGTTCCGACGTCCGAACCTGAGCCGATCGCGGCAATTGCGCGCCCTTGGCCGCCCTGCCCACCCTGCCCGTGCAATTGCCGCGAATCGCTCGG

>NZ_CP040695|6|6|906186-906308|CRISPRCasFinder
CCCTGCCCGTGCAATTGCCGCGAATGGCTCGG	TTCCGACGTCCGAACCTGAGCCGATCGCGGCAATTGCGCGCCCTTGGCCGCCCTGCCCA
CCCTGCCCGTGCAATTGCCGCGAATCGCTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_148240377.1|918028_918991_-|Ku-protein	unknown	unknown	gnl|CDD|238408
NZ_CP040695.2|WP_138875196.1|908237_910103_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP040695.2|WP_137292458.1|920016_920949_+|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|236599
NZ_CP040695.2|WP_148240374.1|899410_900343_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137292440.1|894546_894918_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137292447.1|900417_901245_+|tryptophan-2,3-dioxygenase	unknown	unknown	gnl|CDD|188272
NZ_CP040695.2|WP_137292442.1|896497_896848_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240378.1|919084_920020_+|DNA-ligase	unknown	unknown	gnl|CDD|236599
NZ_CP040695.2|WP_137292596.1|893206_894517_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240376.1|916742_917969_+|DUF222-domain-containing-protein	unknown	unknown	gnl|CDD|238038
NZ_CP040695.2|WP_148240373.1|895049_896501_+|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	unknown	unknown	gnl|CDD|274360
NZ_CP040695.2|WP_138875199.1|915052_916582_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP040695.2|WP_138875192.1|898682_898910_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_148240375.1|901311_906162_+|NAD-glutamate-dehydrogenase	unknown	unknown	gnl|CDD|377452
NZ_CP040695.2|WP_138875198.1|913943_915017_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP040695.2|WP_137292452.1|913044_913944_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP040695.2|WP_138875191.1|896998_898636_+|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143441
NZ_CP040695.2|WP_138875197.1|910206_912915_+|M1-family-metallopeptidase	unknown	unknown	gnl|CDD|341066
NZ_CP040695.2|WP_138875195.1|906447_908241_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP040695.2|WP_138875193.1|898894_899365_-|DUF2505-family-protein	unknown	unknown	gnl|CDD|378476

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_148240377.1|918028_918991_-|Ku-protein	gnl|CDD|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	9.62281e-121
NZ_CP040695.2|WP_138875196.1|908237_910103_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.14606e-169
NZ_CP040695.2|WP_137292458.1|920016_920949_+|ATP-dependent-DNA-ligase	gnl|CDD|236599	PRK09632, PRK09632, ATP-dependent DNA ligase; Reviewed.	9.93014e-132
NZ_CP040695.2|WP_138875198.1|913943_915017_+|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	3.90949e-25
NZ_CP040695.2|WP_138875193.1|898894_899365_-|DUF2505-family-protein	gnl|CDD|378476	pfam10698, DUF2505, Protein of unknown function (DUF2505). Members of this family are all Actinobacteria. The function is not known.	1.74943e-40
NZ_CP040695.2|WP_138875191.1|896998_898636_+|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl|CDD|143441	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), families 4 and 17: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), also known as ALDH4A1 in humans, is a mitochondrial homodimer involved in proline degradation and catalyzes the NAD + -dependent conversion of P5C to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Also included in this CD is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences.	0
NZ_CP040695.2|WP_148240378.1|919084_920020_+|DNA-ligase	gnl|CDD|236599	PRK09632, PRK09632, ATP-dependent DNA ligase; Reviewed.	4.66563e-79
NZ_CP040695.2|WP_148240373.1|895049_896501_+|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	gnl|CDD|274360	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT. This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity].	4.89514e-122
NZ_CP040695.2|WP_138875199.1|915052_916582_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.00461875
NZ_CP040695.2|WP_148240375.1|901311_906162_+|NAD-glutamate-dehydrogenase	gnl|CDD|377452	pfam05088, Bac_GDH, Bacterial NAD-glutamate dehydrogenase. This family consists of several bacterial proteins which are closely related to NAD-glutamate dehydrogenase found in Streptomyces clavuligerus. Glutamate dehydrogenases (GDHs) are a broadly distributed group of enzymes that catalyze the reversible oxidative deamination of glutamate to ketoglutarate and ammonia.	0
NZ_CP040695.2|WP_148240376.1|916742_917969_+|DUF222-domain-containing-protein	gnl|CDD|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	3.16752e-14
NZ_CP040695.2|WP_137292447.1|900417_901245_+|tryptophan-2,3-dioxygenase	gnl|CDD|188272	TIGR03036, trp_2_3_diox, tryptophan 2,3-dioxygenase. Members of this family are tryptophan 2,3-dioxygenase, as confirmed by several experimental characterizations, and by conserved operon structure for many of the other members. This enzyme represents the first of a two-step degradation to L-kynurenine, and a three-step pathway (via kynurenine) to anthranilate plus alanine. [Energy metabolism, Amino acids and amines].	3.99882e-68
NZ_CP040695.2|WP_138875197.1|910206_912915_+|M1-family-metallopeptidase	gnl|CDD|341066	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains mostly bacterial and some archaeal M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	1.20327e-103
NZ_CP040695.2|WP_138875195.1|906447_908241_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.66496e-136
NZ_CP040695.2|WP_137292452.1|913044_913944_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.29475e-101

Protein sequences

>NZ_CP040695.2|WP_148240375.1|901311_906162_+|NAD-glutamate-dehydrogenase
MSTTTHDADKAELLAKAADLAKHGKGSGGPPHDDVHGLLQAYFRHVAPEDVLDRSDADVYGTLASHYKLADVRAQGTAQVRVVTPVSAEHGWSAGGHSVVEVVVDDMPFLVDSLTMELSRQLRDVHLVVHPNFDVERTLTGELVSVTPVADGASEPDDGRIRESWMHVEIDRLREDDDPATIVEDVQRVLRDVREAVEDWAKMNERVAAITAELREDPPPLDPEELRQSGELLTWLAEGHFTFLGYREYTLDRAEVDGVEDDVLRAVPGSGLGILRSDQHLSESFGRLPDPVKAKAREKTLLVLAKANSRATVHRRAYLDYVGVKTFGDDGEVTGERRFLGLFSSAAYTESLLRIPLVREKVQAVLHRSGFDPQSHAGKALLDTLETYPRDDLFHTPIEELGPLAEAAMQARERRAVRMFIRKDTYGRYVSVLVYLPRDRYNTGVRERFVQILKDRLGADDVEFNVRINESTTARVHFVVHQPAGESIPDIDTADLERRLAEASRSWRDDFTSAVIAEYGEEVGAILGRRYLDSFPEAYKEDFPPRVASVDLGRLEGIDGDEGIDHSLYQDVDAGRGEARLKLYRIGSPLSLSQILPMLSSMGVEVVDERPYTLTGVERPSHIYEFGLRYPGTLPEEGRVLFQDAIRAVWDGYTEIDGFNALVLGARLTWRQAALLRAYAKYMKQGGTPFALDYIEDALSSNVDITRMLVDLFEARFDPDRDRSEEAGVEQQILAALDDVASLDHDRILRSYLTHVQATLRTNYFQLTSAGGPHTFISLKLEPSAIPDLPEPRPAYEIFVYSPRVEGVHLRFGAVARGGLRWSDRRDDFRTEVLGLVKAQMVKNTVIVPVGAKGGFFAKHLPDPSVDRDAWLAEGIACYKTFISGLLDVTDNLVDGVTVPPERVVRHDGDDSYLVVAADKGTATFSDIANGVAKSYGFWLGDAFASGGSVGYDHKAMGITARGAWVSVQRHFREMGVDCQSEDFTCAGVGDMSGDVFGNGMLCSEHIRLVAAFDHRDIFIDPDPDAAASFAERRRLFELPRSSWQDYDASLISAGGGVFPRSAKSIRLTPEIRAALGIDDGVEKMTPAELMRAILLSPVDLLWNGGIGTYVKSAEETHGDAGDKANDPIRVDGGQLRARCVGEGGNLGMTQLGRIEYARNGGRVNTDFIDNSAGVDTSDHEVNLKILLDRVVASGDLTEKHRNAVLAEMTDEVAGLVLRDNYEQNLALANADSNAVPLLHVHESWMKRLERDGVLNRELEALPTSRQVRRRIERGEGLSVPELSVLLAWTKIVLATELIDSDLPDDPYLDLDLRSYFPTAVRERFADRIVDHPLRREIIVTQVVNDLVNGAGMTYWPRLAGETGASAAELTRANFVAREIFGSLALREEIATYDNDLDAAVQTHMRIEMRTLVERGSRWLITNRRPPLDSQGLVDTFSGPMQAAMTELPDLLVGSELASYEQRRAALVERQVPEDLASRVAMLPTAYQLLNVIEIASREGLEPADVARVHFALAERLGLPLLVQQILTLPRDDQWQTMARATLRDDLHSVHAQLTAQVLADSAADDPAADRIAAWEDGDDVRVTRAAETVAQICADGEVDLARMSVGLRVVRSLLA
>NZ_CP040695.2|WP_137292447.1|900417_901245_+|tryptophan-2,3-dioxygenase
MSDENREQFVSFGEQGAQLTYGSYLRLPVLLDAQHLESDPPAHDELLFITIHQVYELWFKQLLHEVVAARDTMLAAAAEGDPASGLWRAQHLLARVHVIERVLVHQVDVLETMTPQDFLEFRQRLAPASGFQSVQFRELEFLSGAKDPAYLRRFRGLTDDEQARLRARLDEPTLWDAFVAVLRARGLPADDDEQVADAVRTAAHDRDRHAAVWALAEALLQHDELAASWRARHVVMVERMIGAKSGTGGSSGSAYLRGRLPLQYYPVLWDVRSML
>NZ_CP040695.2|WP_148240374.1|899410_900343_-|hypothetical-protein
MNRTPTRSRPRRPAVATILVPLLATVLVACGSEADDEPAPAPSAGPSSTDAPPTDDATTGGPTGGGPTGGGSTGEADLGAATEALETADTGRFRLSLDNAGETLQTKDGIYRLTDGASYSTTVVIRADQSVTTRTLAVDGVVYTQVDQPEGVAFDQCWIRYDQETLRELSPGYEGGAPPNEVTTLLGARIDGDRVTAPLDDVVGSLGTRFLQILGLGAGGSGETPIEVAIQDGVPVGWRTTFADLVASSTAAGNTPVDGVDSVGAAQLVVNLSELGSPVDLTAPPARLQVPFDRDVPTLEDAVRTCESRT
>NZ_CP040695.2|WP_138875193.1|898894_899365_-|DUF2505-family-protein
MAKSIRHEMPYDAPVEAVAAMLTDPAFREEVCRAQGAVRHQVSVEGTTVTIDQWLPTAGVPSFARKIVGDETNIVQVERWDTPSRGDIEVSIPGKPGDMRGSAVLVPSGTGTLETVELTVKVSIPLVGGKLEGLIADLLLKALKAEHRTGIAYLSR
>NZ_CP040695.2|WP_138875192.1|898682_898910_+|hypothetical-protein
MTPLHLGPLHPVEQALTLVLAFGPFVVLAIVVWLRRRADAAADPAEAGTEAEVQGEDGTEGGAEGAAAERPQRDR
>NZ_CP040695.2|WP_138875191.1|896998_898636_+|L-glutamate-gamma-semialdehyde-dehydrogenase
MDAITTPPAPTNEPNLTYAPGSPERAALVVEIEKLESRQHTFPAHVGGRRRDGGGAEVNVVQPHDHQHVLGTLKNATTKDAEEAVGAAKDAALPWQRMPFDERCAIILKAADLLAGPWRQRINAATMLGQSKTAFQAEIDAACELIDFWRFNVHYAKQILAEQPIANSPGIWNRTDHRPLEGFVYAITPFNFTAIAGNLPTAPALMGNTVVWKPSPTQQLAASLTMELLEEAGMPPGVINMLPGDGLDVSKVALTHPDLAGIHFTGSTPTFQHLWRTVGENIASYRSYPRIVGETGGKDFILAHPSADPDVLRVAMIRGAFEFQGQKCSAASRAYVARSVWDKMKDQLLHDVESLTMGDVTDLSNFMGAVIDDRAFAKHRTAIARVAGNDHLTTLAGGQTDDSVGYFVRPTVVASTDPADEMFSTEYFGPILVVHVYEDRSYDQVLTQLESIASYALTGAIIAQDRQAIADARRDLRFAAGNFYINDKPTGAVVGQQPFGGGRASGTNDKAGAASNLLRWTSPRSIKETFVPPTDHRYPHMDAEG
>NZ_CP040695.2|WP_137292442.1|896497_896848_+|hypothetical-protein
MTRVYLPTTLDRLRDAWSAGAVPVPDADAVVVAEGEDEESEYAALMTAADVSAELLAGPGRRVVVVAEVADPTAGHPVPLKRVLAVHADAADRPADADPDDDLAWYATQEVPDLLG
>NZ_CP040695.2|WP_148240373.1|895049_896501_+|wax-ester/triacylglycerol-synthase-family-O-acyltransferase
MVERLRARDLAFLTAETVVAPRHNATVEVFEPGPAGFDHARLLEIVSDRISFVPRYRQRLVEVPGRLATPVWVDDEHFDLGYHVRRSALPRPGSDDQLRELVARIVSRRLDRSRPLWEIYVVEGLAEGRFALLTKSHQALVDGVHTVDLGQLLLDAVAEPRPLEPDDWTPRSVPSALRLVAGAVRDSVTAPATFVDTVSVTTGSVLRTAERASSRAKVVADALTGRRPRRRAMEGPLSQQRRVVTVATELADHRRIRDAHGGTVNDVVLATIAGGLRAWLMTRGEPLGGARHMRALVPVSVVDEELEATSLGQIAPHYVNLPIGEASPLVRLHQVSYSFQAHADTGRGVAANRIAGIAGFAPTTFHAIGARVAATEVRRGYQLCVTNVPGPQTPLYLAGARMIATYPVPPLLEDHPLAIGVTSYDGRVFYGMNADRDQLPDADLLGTCLREALDELLSTTTATRAPRGRRRPSSRRPSEGGTS
>NZ_CP040695.2|WP_137292440.1|894546_894918_-|hypothetical-protein
MTGSTTRRGAAATAVLALLLTTSACGGDDGGGSTEVKVIEVTLEAGAVTPDGDRIDVDVNQPIDLVVTADEPGELHLHSSPEQTFEFEAGENAPIELQFDRPGLVELELHEPASLPVLELQIS
>NZ_CP040695.2|WP_137292596.1|893206_894517_-|hypothetical-protein
MSAHGIGGQQDLPISLGLAIAGAVAALVVSFTILAVAWRKPRYDAATSGRPAPEAVQRLVAHPAFAIALRVFGMVLFLYTAFVALFGVDKVINPIFGIFFVWLWVGIVPMSLLLGPFWKAISPVRTINLLLARVVGSDPDEGLHRYPDRLGYWPAAVGLYAFVWFELVYPYMSDLSPVRFWCAVYVAAMLLGGALYGNRFYENADPFEVYSTLVGKLSIWGERDGVLLVRSPLANVDSVRVAPGLVAVVGVLVGSTGFDSFGESPTWVRFLQGTQVSGYLLDNLALLGFCLAATGIVAVASMLTGVHTDQRRSDLPNLFAHSIIPIVVGYVVAHYLSYFVEVGSRYLVLASDPLSNGADILGTGGWTGIVWLGYHPTLLANLKVGAVVVGHVVAAVVAHDRALRLLPARHQLTGQLPMLFAMVGITSGGLFLLFSS
>NZ_CP040695.2|WP_138875195.1|906447_908241_+|ATP-binding-cassette-domain-containing-protein
MATTSHDVGLDPDPDQPPAASVRFLWRLRGYLRPHLGSVAVMLLTSLAVVGTSIGIPLVTRAVIDGPIADHELGPVLPLGLLALALGVVEAVLIFVRRWVQSTAVLAMETSMRHDLYTRLQELPMSFHSRWPAGQLLSRAIQDLSSIRRFSGFGLIFLVVNIVQVVAVTIVLLGMYWPLGLVVAATAAPIVWLSMTFEKKYVVMSRRVQDQQGDLATLAEEGALGFRVIKAFGRSEHVASEYERQARSLHASSMDKVHLSARFWTFLEVIPNLAVCVVLLLGAIGAGQGALTTGELVAFITLLLSLVWPVSSLGVILAMAQEAMSASARILEVLDTEPAIVGGDRTIAEPRGHLRFEHVDFAFPDAPDEVVLRDVCLDVPPGETVAIVGGTGSGKTALTALVPRLHDVTAGRITIDGVDVRDLELGHLRSLVATAFEEPTLFSMSARENLTLGRAEAPEADVEEAIDVAQAGFVRDLPWGLDTRIGEQGMALSGGQRQRLALARAVVARPRILVLDDTLSALDVHTERLVEDALRAVLGSTTGIVVAHRASTVLLADRVALLQDGTITHVGQHRTLLAEVPAYRELLSADAGDRVPA
>NZ_CP040695.2|WP_138875196.1|908237_910103_+|ATP-binding-cassette-domain-containing-protein
MSTDTSTGTGTSTGTDADQSWRGIAAGEADAIDSADRIRFTGGSGQLLRELLRPYRRAIWILVAVVVVENAARLAIPYLVKVGIDSGIPPIRESDDLGPLGIVVALVLGATVVQAITRQIFLVRSGRIGQDLLYQLRRRVFRHFQRLSPAFHDDYTSGRIISRQTSDIDAIYEMLETGFDGLVTAFLTLVGTAVILMFLDVKLGLLALLCGPFLFWITAWFRRESAKSYRVARERVALLIVHFVESMGGIRAVQAFRREPRDLEIFDVLNDDNRRANLVAFRLVAWFMPGVRLIGNITIAAVLVYGGYLAYQGEVTVGVLAAFLLYLRRFFEPMMEISQFFNTFQSASAALEKLAGVLRVEPSVPEPATPVPLAHRRGGLTFEQVRFSYVDGRDVLPGLDLDIPGGQTVALVGTTGAGKTTLAKLATRFYDPTSGRVLLDGVDLRDLASDDLRSSVVMVTQENFLFTGSIADNIRFGRPGASDADVEAAARALGAHDLIMALPDGYATQVANRGGRLSAGQRQLVAFARAFLADPEVLILDEATSSLDVPSERLVQHALRTVLAGRTAVIIAHRLSTVEIADRVLVMAHGDVVEDGTPADLVAGGEGHFSDLHRAWLDSLA
>NZ_CP040695.2|WP_138875197.1|910206_912915_+|M1-family-metallopeptidase
MTKPRPRSTRISARLLTPLVAIAAVALPAAAPAHAEDPVAGAQTSGDSLFPHVGNGGYDVQHYDLDIAWTPGATLALSTIAATTSIEASTTGAPLSSFSLDFERGGLAVSSVTVNGVPAAFAHDEVPADIKHKLVVTPATPVSGAFTTVVTYSGIPTRHTDADGSYEGWNVTADGATFVNQPIGSMTGFPNNNTPADKATYTIDVDIPTTITNAAGTGAAAAASNGELVGKDVAGDRTTWRWVQQEPMASELAIISIGKYDVLESDVTLASGRTLHEWSFVDSASSAANKNSVGVQRARFKSVIDGLESRFGPYPGNSIGVVVDLVPSAISYALETQDRSFFPTSINAGTFVHELAHQWYGNNVAPTVWNDLYINEGMATWMPTHFANQLAEPATSGASTEYTYFTSWSASAPESANWLTPPAGITDAAGLYGYQTYTRSAQFWEALRLSIGDADFFALIREWQVRHAGQSRGTAALLALAEEVSGAELDAFFQDWVRDADKPAWPQRYDLVLGQDTADGALEPGDTVTYTVTAANRGYVPLTSSVAEVDLSDVLDDATLGALPDGLTLAGDTLTWALPTTPRHGSRTASFDVVVDGDVSAASLRASLSSQTLGGFCAPGASCTTRADVAEQAVAPAPLPTITGTPKVGAELTADTTGWAPGTTFAFGWTVGGEDVVDATGPTLLLGPDDAGKVVRVTVAGSKAGYGDVTRTSAATAAVAAGDLTTTPTPTVTGTARVGVPLTAVAGTWDDGVTLAYRWTRDGAPITGATAATYTAVAADAGRRLGVVVTGTKPGFAPTEVASADTAPVALGQQVRRPTPTVAGRAAVGRTLRAVPGARDAGVTLTYRWFVGGKAVAGARGAGRTFAVTRAARGKRVVVVVTATRPGYVTVTGRSPRTAKVV
>NZ_CP040695.2|WP_137292452.1|913044_913944_+|ABC-transporter-ATP-binding-protein
MAAIEVDGLVKRYGDLRAVDGVSLEVAEGEFVGILGPNGAGKTTTLEMIEGLRQPDEGSVRVLGEAVWPRNPRLLPRMGVQLQASAFFERLTAREQLRTFASLYSVPVTAAEEWLERVGLVEKADTRVEDLSGGQAQRLSIACALVHDPEVVFLDEPTAALDPQARRNLWDLLAGLNDSGRTVVLTTHYMDEAEVLCDRVAIMDAGRVLEVDTPAALVRGLDAPTRVSVGPGQVSLDEARAIDGVDEATESVDGVVLTTRSPAAVLTRLAEQDRLDGVQIRTATLEDVFLDLTGREYRA
>NZ_CP040695.2|WP_138875198.1|913943_915017_+|ABC-transporter-permease
MPATTATFRALSLAIIKGFLRDKASVFFALIFPLMFLVLFGGIFGDQGQSRVELVQVGDVSLVDDLPAGAREVFDDTFDVTRSDDLAAALEEVRRGDADVAVEMRGDTLVAHYTQTDQVGAAITQGTLRSFVDGANVAATGSPPTYTLETERVEDDSLTTIQFVTPGLLGWAVAMSAAFGAAATIQGWRQSKLLRRLQLAPVSTRTVVGARVAVAIGIAFVQMAIFLGLGAGAFGLQLTGSWWMSIPLLVVGTLCFMSVGLLAGAITTTTEGAVNAANFMVLPMAFLSGSFFPLDAAPAWLRAVSNVLPLKHLNEGMLDVMVRGQGPGSAVLPIVILAGFALVVSLVAARLFRWETA
>NZ_CP040695.2|WP_138875199.1|915052_916582_+|hypothetical-protein
MELHEHLYDLGVRRGDAVFDDADVLRGALEGSFADVSTAAERGLLVDAVRSGVFGFLVDRLVAGVPVDEAVGDAGDRLARVPGGDPAAARWACAALAYAVGRADDADVRRHPRPGAAPGAGPGAGPEPHLAPDDTRERMPAVPALAPTSIPVPVPAPVPLEGREDVVSRAGSRAERGGARRRWPVVAAAVLVLALVAGVVAAVVLGGDEEPAPTGGGVTTPSASPSETETETIDPDGTDPAAVNARYSGLAEAVVPDDVMCTTAGRARARGERLTCELPTGTLELVTYPSAAALEAAREERVEHDIGTVYEATTSGTLMAFEREDDAGAPVRAAVYWDDAVAQQSATLTGPRGTDLDDLVAEVRARVPSVAYPTGPSAPGLVDFLGGWLDVEKCLRIETAVDLELEESFCDPTGPVEVFVGRFESEEALEAYRALTLAVAKDSERPLRTWEARRGKDDGALYEYTTAAGRPVRYWDLPGCACYAEATLTRGDADKLATWWRRGPGVEGD
>NZ_CP040695.2|WP_148240376.1|916742_917969_+|DUF222-domain-containing-protein
MAAATAQLADPALVAVRTHQAATRRAEVATLVSVLDWAREHTTDDDPHTVTFGERPLPLGGVGCPVVEEFAAYDLAAAMGMSTDAGLGYLGRALELRYRLPRLWAAVLDGRLPVWKAGRIAESTMRLPVDGAAYVDARLAQAVSSITFTQLDRLVTEALARHAPQDVAPPADERYVAIDLTHATLDGNARLEGVLSVPDAMDLEDALRTGAATLAEAGCEEPLDVRRSIALGDLARGDQPLDLTSQPTRPLVVHLHQDSPDLGRSETTRSPVTVETIQTWCATATHVTIKQVIDLHDHVHVEAYEAPDRLREQIELRDLTCAFPHCRRPATRCDLDHITPHDLGGPTSTDNLAPLCRRHHRAKTHGRWRYTTTTPGTYHWTAPSGLTYRRDHHGTTPLDPPPAEPAEP
>NZ_CP040695.2|WP_148240377.1|918028_918991_-|Ku-protein
MRAIWKGAVSFGLVSVPVKLYSATESHDVSFRQVHASDGGRIKYQRVCAIDGEEIAYADIAKGYETEDGEMVILSDDDMAQLPSTSSREIAVEKFVPTDQIDPMLFEKSYYLEPEKSGAKPYALLRQALIDADRMAVVTVALRQRTTVAVLRVRDDVIVLQTMMWPDEIRQPDFTIDTGEIKDSEVKMANMLVETLAGDFDAGDFEDDYADAVQELVRTKIEGGEIKRTPTSTKSSGEVVDLLAALQRSVQNAKSARGEATDADDDSDDGTDEKPARKTAAKKAPAKKAPARKTAAKKAPAKKTAAKKTTTRKTAAKKAS
>NZ_CP040695.2|WP_148240378.1|919084_920020_+|DNA-ligase
MRPMLATKGDHVPTGEEWAHEVKWDGMRILADTRPAGRAGGSGTRLTSRNDNDVTAAWPDVADAPLADRDHLVDGEVIALNERGLPDFRVLQERMHVRRATSVARLVHQVPVTFMIFDLLRLDGRDLLAEPLATRRALLAETFEGSAWQVPPSYDDGPMLLDATREQGLEGIVSKRLSAPYRPAERSPHWLKFAHRHRESFVVGGWRPQEGTTDRLAALLVGEPTPDGLRYRGRVGSGIAARQSRVLAEAVAGLARADSPFADEVPRVDALGTRWCEPVLVVDVDSHGRGYDRLRQPSFRGLRTDLGAADL
>NZ_CP040695.2|WP_137292458.1|920016_920949_+|ATP-dependent-DNA-ligase
MSPRERPQQRVEKEELHVDVDGRTLKISNLAKVLYPRTGTTKGEVLDYYARISPTMLPHLRDRAVTRIRWPHGVQDASFFEKNVPPGTPSWVRTVTVPTTGSRGSSRHGDTLVFPVVDDLATLTWMANLAALELHVHQWRVGRNGRPRNADRVVVDLDPGEPAGLHECCQVALLARDKLAERDLVAKPVLSGSKGLHLYADLPRRLPPDESTALAREIAEELQGEHPKLVTATMTKAKRGGKVFFDWSQNAGSKTTVAPYSLRGRERPYVAAPVAWDEVEEGAEDPLGLEQLRHDEVLDRVADLGDLFAG

Crispr_ID: NZ_CP040695_7

• CRISPR_ID: NZ_CP040695_7
• CRISPR_location: 1041891-1041983
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_7

Consensus_repeat	Method
GTCGCGCTGACGCGGATCCCGGTCGTCA	CRISPRCasFinder

spacers of NZ_CP040695_7

>7.1|1041919|37|NZ_CP040695|CRISPRCasFinder
TGACGCGGATCCCGGTCGTCGCCGACGCGGATCCCGG

CRISPR arrays and Neighbor proteins around NZ_CP040695_7

CRISPR arrays

The CRISPR arrays of NZ_CP040695_7

>merge|NZ_CP040695|7|1041891-1041983|CRISPRCasFinder
GTCGCGCTGACGCGGATCCCGGTCGTCATGACGCGGATCCCGGTCGTCGCCGACGCGGATCCCGGTCGTCGCTGACGCGGATCCCGGTCGTCA

>NZ_CP040695|7|7|1041891-1041983|CRISPRCasFinder
GTCGCGCTGACGCGGATCCCGGTCGTCA	TGACGCGGATCCCGGTCGTCGCCGACGCGGATCCCGG
TCGTCGCTGACGCGGATCCCGGTCGTCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138875263.1|1038176_1039115_+|MOSC-domain-containing-protein	unknown	unknown	gnl|CDD|225758
NZ_CP040695.2|WP_138875267.1|1044007_1044892_+|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl|CDD|223344
NZ_CP040695.2|WP_138875258.1|1029755_1030772_-|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NZ_CP040695.2|WP_138875261.1|1034523_1036248_+|CHAP-domain-containing-protein	unknown	unknown	gnl|CDD|377495
NZ_CP040695.2|WP_138875268.1|1046358_1047795_+|trigger-factor	unknown	unknown	gnl|CDD|234956
NZ_CP040695.2|WP_148240394.1|1042018_1042588_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138875259.1|1030836_1031223_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138875262.1|1036276_1036903_+|disulfide-bond-formation-protein-DsbA	unknown	unknown	gnl|CDD|239320
NZ_CP040695.2|WP_138875264.1|1039124_1040945_+|methionine--tRNA-ligase	unknown	unknown	gnl|CDD|237029
NZ_CP040695.2|WP_137295680.1|1052995_1053985_-|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NZ_CP040695.2|WP_137292562.1|1036987_1038157_+|hypothetical-protein	unknown	unknown	gnl|CDD|128941
NZ_CP040695.2|WP_137292555.1|1029339_1029756_-|globin	unknown	unknown	gnl|CDD|381280
NZ_CP040695.2|WP_148240395.1|1047884_1049609_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP040695.2|WP_138875266.1|1043511_1044015_+|ribose-5-phosphate-isomerase	unknown	unknown	gnl|CDD|235509
NZ_CP040695.2|WP_148240396.1|1049676_1051782_-|hypothetical-protein	unknown	unknown	gnl|CDD|376628
NZ_CP040695.2|WP_138875270.1|1051778_1052972_-|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
NZ_CP040695.2|WP_137292558.1|1031209_1031590_+|DUF5130-family-protein	unknown	unknown	gnl|CDD|379937
NZ_CP040695.2|WP_138877068.1|1045092_1046049_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP040695.2|WP_138875260.1|1031823_1034391_-|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NZ_CP040695.2|WP_138875265.1|1042729_1043473_+|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl|CDD|369561

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138875263.1|1038176_1039115_+|MOSC-domain-containing-protein	gnl|CDD|225758	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only].	2.30663e-54
NZ_CP040695.2|WP_148240395.1|1047884_1049609_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.89775e-80
NZ_CP040695.2|WP_138875258.1|1029755_1030772_-|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	3.89807e-47
NZ_CP040695.2|WP_138875268.1|1046358_1047795_+|trigger-factor	gnl|CDD|234956	PRK01490, tig, trigger factor; Provisional.	5.79607e-141
NZ_CP040695.2|WP_138875267.1|1044007_1044892_+|Fpg/Nei-family-DNA-glycosylase	gnl|CDD|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	2.66382e-64
NZ_CP040695.2|WP_138875261.1|1034523_1036248_+|CHAP-domain-containing-protein	gnl|CDD|377495	pfam05257, CHAP, CHAP domain. This domain corresponds to an amidase function. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of Escherichia coli gss, where it functions as a glutathionylspermidine amidase EC:3.5.1.78. This domain is found to be the catalytic domain of PlyCA. CHAP is the amidase domain of bifunctional Escherichia coli glutathionylspermidine synthetase/amidase, and it catalyzes the hydrolysis of Gsp (glutathionylspermidine) into glutathione and spermidine.	1.014e-13
NZ_CP040695.2|WP_138875262.1|1036276_1036903_+|disulfide-bond-formation-protein-DsbA	gnl|CDD|239320	cd03022, DsbA_HCCA_Iso, DsbA family, 2-hydroxychromene-2-carboxylate (HCCA) isomerase subfamily; HCCA isomerase is a glutathione (GSH) dependent enzyme involved in the naphthalene catabolic pathway. It converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1,2-dihydroxynapthalene by a dioxygenase, into cis-o-hydroxybenzylidenepyruvate (cHBPA). This is the fourth reaction in a six-step pathway that converts napthalene into salicylate. HCCA isomerase is unique to bacteria that degrade polycyclic aromatic compounds. It is closely related to the eukaryotic protein, GSH transferase kappa (GSTK).	2.32587e-06
NZ_CP040695.2|WP_138875264.1|1039124_1040945_+|methionine--tRNA-ligase	gnl|CDD|237029	PRK12268, PRK12268, methionyl-tRNA synthetase; Reviewed.	0
NZ_CP040695.2|WP_137295680.1|1052995_1053985_-|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.11661e-83
NZ_CP040695.2|WP_137292562.1|1036987_1038157_+|hypothetical-protein	gnl|CDD|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	6.45645e-34
NZ_CP040695.2|WP_137292555.1|1029339_1029756_-|globin	gnl|CDD|381280	cd14771, TrHb2_Mt-trHbO-like_O, Truncated hemoglobins, group 2 (O); Mycobacterium tuberculosis hemoglobin O like. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P). This group includes a Mycobacterium tuberculosis TrHb2, Mt-trHbO, encoded by the Mycobacterium tuberculosis glbO gene, which is expressed throughout the Mycobacterium growth phase. It also includes a TrHb2 from the thermophilic Thermobifida fusca ( Tf-trHb) which has a high thermostability and at the optimal growth temperature for Thermobifida fusca (between 55 and 60 degrees C ), it is capable of efficient O2 binding and release. Tf-trHb shares a relatively slow rate of oxygen binding with Mt-trHbO.	6.94596e-61
NZ_CP040695.2|WP_138875266.1|1043511_1044015_+|ribose-5-phosphate-isomerase	gnl|CDD|235509	PRK05571, PRK05571, ribose-5-phosphate isomerase B; Provisional.	2.04634e-73
NZ_CP040695.2|WP_148240396.1|1049676_1051782_-|hypothetical-protein	gnl|CDD|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	8.58843e-21
NZ_CP040695.2|WP_138875270.1|1051778_1052972_-|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	5.66541e-28
NZ_CP040695.2|WP_137292558.1|1031209_1031590_+|DUF5130-family-protein	gnl|CDD|379937	pfam17174, DUF5130, Domain of unknown function (DUF5130).	1.99856e-11
NZ_CP040695.2|WP_138877068.1|1045092_1046049_+|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.12226e-29
NZ_CP040695.2|WP_138875260.1|1031823_1034391_-|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP040695.2|WP_138875265.1|1042729_1043473_+|alpha/beta-hydrolase-fold-domain-containing-protein	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.05001e-61

Protein sequences

>NZ_CP040695.2|WP_138875264.1|1039124_1040945_+|methionine--tRNA-ligase
MTHVLSAVAWPYANGPRHIGHVAGFGVPSDVFSRYSRMAGHDVLMVSGSDEHGTPILIAADEAGVSPQELADRNHRIIAEDLVSLGCTYDLYTRTTTRNHHAVVQELFLGVYENGYFVEQTTYGAISPSTGRTLPDRYIEGTCPICGAGGARGDQCDTCGNQLDPADLIDPVSKINGETPEFIETQHFFLDLPALADALGEWLDGRAATGLWRPNVIRFSQNILKEIRPRAMTRDIDWGIAVPLDGWRENPTKKLYVWFDAVVGYLSASVEWARRSGDPEAWRKWWNPATAGGAGGSEALSYYFMGKDNITFHSQIWPAELLAYSGRGSKGGEPREYGELNLPTEVVSSEFLTMEGRKFSSSKKVVIYVRDLLSRYQPDAFRYFVAAAGPENQDSDFTWAEFVRRTNDELVAGWGNLVNRTATLIAKNFGEIPPAGVLTEDDERVLAVAEQAFTVVGDLIGRHRQKQAIAEAMRAVGEVNKYVSDTEPWKLKGEDQRERLGTVLHVVAQCVADLNLVLAPFLPFSANAVDRVFGGAGDVAPMPRIEEVDDLDGGAGYPIITGDYTTAPAWQRRAVVVGTPVEKPTPVFTKLDVAVVDEELARLAGG
>NZ_CP040695.2|WP_138875263.1|1038176_1039115_+|MOSC-domain-containing-protein
MAVPISLTSLRRYPVKSCRGEELPTATVRPWGLDGDRRWMVVDHAGAAITAREVNRLLLLDPQLTATGLRVEARDGAAGGAGGAGGAAIAPLEVATPDPAHQVPVSLWSSRLTAAAAGAEADAWFSEVLGTDARLVHLDDPTRRPTTPDYGDEGDVVSLADGYPLLLATEESLAAVNDQVLAAAPHGREPLTMTRFRPNVVVSGAAAWSEDDWRRIRIGDVVLRAVKGCARCVITTIDPDTAVREKEPVAAMARIRRFDNKTWFGTNLVPDVPAGGDGVVVRVGDEVEVLDAVEPGAGPLRVPTRNAVARAH
>NZ_CP040695.2|WP_137292562.1|1036987_1038157_+|hypothetical-protein
MPSLTTPPGRRSAALGAVVAAALTAPTLAVTAAPPGSGASAAPAPVRAEPPVQRLDPAGAGLRAADVPLPADRRTVETATPFAMVGVTWTDDGADRAVRVRTRSEDGWSSWRGLEQIGDGPDRRTRERSAGVAATDLQWVGTADAVRVDVAGARPADLTLVLIAPDGTQVRSPARPQPRLLARDTRNPWSPKPAMRGRAQWGADPALRSGAARYNSTIQQVHVHHTVNSNTYARDDVPGLLRGIYRYHTQNLGWSDIGYNFLVDRFGRTWVGRAGGPRKPVLGAHTLGFNSTSTGVAVIGNFEDARPRRNVVSALVRLSAWKLDRYDRKPRGRVSVTSSGSDRFPAGERPRLPTIDGHRDTNQTACPGERLYAELPTIRRRAAARIARW
>NZ_CP040695.2|WP_138875262.1|1036276_1036903_+|disulfide-bond-formation-protein-DsbA
MSTPTTADFWFDPLCPFAWITSRWILEVEQVRDIQVTWHVMSLGYLNQDKDISEEYRELLAPAWGPVRVCIAAEQKHGREVLLPLYTALGTRIHVDGRTLHEQEDAGRSIIVESLAEAGLEPELVDAMDDSGLDAAVAASHHEGMDQVGNDVGTPTIAIEGAAFFGPVLSKIPRGEDAGLLWDGCVAVAKVPYFYELKRSRTGDLDFS
>NZ_CP040695.2|WP_138875261.1|1034523_1036248_+|CHAP-domain-containing-protein
MGLLLRNAPDVLDSGPVPLRRSPLTRRPTRPPTRRPSGLLARLVALVVLGSLAVVVPVANPSPAWASSRYHCSGYSGCANAGYSDDGYGRVNNQMYWRMYSGHNCTNYVAYRMIRAGMSTERPWGGTGMAYNWGLARRDVTDTKPAVGAVAWWNRGVSGAGSSGHVAYVEKVVSSTEIVISEDSWNGDFHWRTIYKDGTGWPTGFVHLADRAPAPTPAVTVRTAPSISDAPKVGVPVRGTWAAFTPKATHTVQWLRNGTAIPGATTSTYTPTGEDAGAVLTFRDTGSRAGHTAAVATSAPSAPVASGAFLRRTSPVVTGDPTVGATLSVVPGAWSPAPASVSVRWSADGVYLSGRNGPTLELTRGLVGKTISAVEVARGPGLPKAFGYSNRVGPVVSGNVAVAQPFAASGTPRHGSTLSFAGASWTPRDAVATYQWLRDGAVVPGAVAPTYLLGAADVGRTIEARATVAKPNFRPVVQAATFGRVTTGAAITLRAGGRKRAVMVRVRVRAPGAVPTGSVVVKVRKRTTTLPLVDGVATIRVDRLPAGRRWVKVTYAGDGLVTGSAAGAWATVKP
>NZ_CP040695.2|WP_138875260.1|1031823_1034391_-|aminopeptidase-N
MPGTNLTRDEAATRAALLDVTSYSIDLDLTTAPDSTTDTFGSTTTIAFTCREPGASTFADLVGATVHELTLNGAPLDPATYADSRIPLPDLQADNLLVVRADCTYSTSGEGLHRFVDPVDDRVYLYSQFEVPDARRVFTTFEQPDLKSVFTFRVTAPDHWKVVSNAPTPEPEALDGGAAVWTFPPTKRMSTYITAVVAGEYHAVFDTYEGQFGEIPLGHYCRQSLVEHLDRDELVKITRQSFEFFERQFGYPYPFEKYDQLYVPEYNMGAMENAGCVTLRDEYLPRSRQPRSFYEFRCSVITHEMAHMWFGDLVTMKWWDDLWLNESFAEWACYWCEAEATEFTDAWTGFANARKQTGYRADQLPSTHPIAADNHDLEAVEVNFDMITYAKGASVLKQLVAWVGLEPFIAGLRQYFQDHAFGNTEFGDLLVALERSSGRELGSWAEEWLQTAGVNTLTPEFELDADGAYTRLAVRQTAAADQPTLRRHRLGIGLYDEVANEQGEPRLVRRDYIEVDVEGESTDIEAAVGQRQPALLLLNDGDLAYAKIRLDERSLATVVGGLSRLDDSLARALVWGATWDMTRDAELSATDFVSLVLANIGSETDAWGVTRIPAYAALAVNSYSAPAHRDELRLQWERGLRGLLDAAEPGSDSQLTFARSYAGAAHTDEALDALESLLDGSLVVEGLAVDDDLRWSLVTALAARGRADDARIDEVLATDNTISGQEHAAAARAAMPTAEAKETAWRLGMLEAGTPNETARSIVLSFMRSGQEEVLAPYVEKYLDLVDSTWERIGAHRGSVALEHFFPKPLASAELLDKVDAYLATTTANPGAVRYVREGRAEVARALAAQAKDAG
>NZ_CP040695.2|WP_137292558.1|1031209_1031590_+|DUF5130-family-protein
MPAGEYLSEADRSSLDVVMRKAEQTCRAEFSIFVGRAQGEPRAFATSLHNSMVAPARSILIMVDPDARSVEVVTGGFVRETLTDAQVELATATMAEAFADGDLVGGLRHGIRQLGEHARTARPRKA
>NZ_CP040695.2|WP_138875259.1|1030836_1031223_+|hypothetical-protein
MTGTVTNHTGDPRGRLHRARRLLTVAGAAGVLVAGSAGAASADVPEGWDTPPSIDTGFALLILLGVPVGLFLLITLLTYLPAMIRGERLAPGGQVPEDQWLGGPRRSPNELAAPDTAESRAGGSSARW
>NZ_CP040695.2|WP_138875258.1|1029755_1030772_-|mechanosensitive-ion-channel
MPVPDIVALGALPRPFGPALVANPCAEGESVCNTVFDQTNNDTLARYSDVLIGKPLALMGLLLLAVTLRWLVHKVIDRIVRRAAHGVLPDRVALGASQRRSQRAEAMGSLLKSIVTGLLVAVFGTMMLSEIGVDIAPIIASAGIVGLALGFGAQSLVKDFLSGVFMIIEDQYGVGDDVDLGEAIGTVEAVTLRMTRLRDVNGTVWYVPNGQIVRVGNQSQNWARTVLDVSVAYHEDLARVRRVLSEVAHDLWEDDDFKGQVIEEPSVWGVQDLGVDGVTVRVVLKTTPGEQWAVAREMRQRIKNRFDYEGIEKPFPQRVVWQREEPARRRPDDVEGGA
>NZ_CP040695.2|WP_137292555.1|1029339_1029756_-|globin
MPPTQDVTIEPDNGGVTFYEEIGGFETVRTVVHRFYEGVATDELLRPMYPEEDLGPAEERFLLFLVQYWGGPTTYSEARGHPRLRMRHAPFAVTPAAKERWLHHFRAGLDAADLTPEQDAKFWDYVTHAAQFMVNSFE
>NZ_CP040695.2|WP_148240394.1|1042018_1042588_+|hypothetical-protein
MTAPSHVPLFYVKQKFAMTTNRYELVGAGAGGAEGQSLGVAQQKRMAFKEEVTFYTDESRSQAVFSFRARKKIDLNAGYDVFDAQGQQLGFFRKDFGKSLLRSTFHLEGPGYQAVGQERSQAVALVRRFADIPFLPIHFDFTTPDGRTVLSVQRQSTVRDRYTVTVGDPALDFRVAAAVAVGLDALMQR
>NZ_CP040695.2|WP_138875265.1|1042729_1043473_+|alpha/beta-hydrolase-fold-domain-containing-protein
MLDLDAGGVPCRLYLPAGAAPGVVVHAHGGGFVFNDVAVHDASCRRLANRTGTAVLSVDYRLAPEHPFPAAVEDLDAVVAWLDEHGEGHGLTGPTYGHGDSAGANLVLVAALRHPDRFRALALVYPFLDPTAAGASHHEEVEGFDPRDVAWYWEQYTGGDARHHADPDLAPLLSDRLGTLPPTFVMTSEHDPLRDEGELLAARLAETGVEVLGVRYLGQVHGFWRHPDAFPAAEPLLRQAAAFLRDH
>NZ_CP040695.2|WP_138875266.1|1043511_1044015_+|ribose-5-phosphate-isomerase
MRVHLGSDHAGLDLKAHLTTWLTDHGYEPVDHGPFVFDAVDDYPVFCLRAAEGVVADRAEGLDSLGVVIGGSGNGEQIAANKVLGCRAALAWSEETASLGREHNDANVVAVGGRMHSLDDMTRFVQVFLETPFSGDERHVRRIGMLSSYDETHVLPPLPASARPGDA
>NZ_CP040695.2|WP_138875267.1|1044007_1044892_+|Fpg/Nei-family-DNA-glycosylase
MPEGHTLHRLAGELTRAFGGRTVAVSSPQGRFADAAALLDGERLVDAQAWGKHLFVEFAGERFVHIHLGLIGGMDVRTDVDPDVGVPPPVGQVRLRIATTDGPDGPDGPDGGALALADLRGAITCALVTAEQRAATLARSGPDPIRADADPDRAWHRIRRSNRTIGALLMDQGVLAGVGNVYRAEVLFRNRLHPLRPGTTLRVGQWQAIWSDLVVLMAEGVVSGRIDTVRPEHTPEAMGRPPRRDDHGGEVYVYRRTGLPCLVCGRQVSTAVLEGRNLFWCSRCQPVFRSRAVG
>NZ_CP040695.2|WP_138877068.1|1045092_1046049_+|SpoIIE-family-protein-phosphatase
MLFPSRTPFSSLVLPVVLGSILLGPRLLPWFVGFDMVMLTICVSRQESLTGRVLGAATVQLAVACVVLLANLQRARLGVAGLRGESMFVDLRDRILDQAHIPDLPAGWQVESALHSAGGTAFAGDFVVASRSADGTSLQVVVVDVSGKGEAAGTRALLLSGAFGALLGALPPAGFLPAANAYLLRQAWDEGFATAIHLCLDLTTGAFEVRTAGHPPAVHRASGTGRWAVLHTEGPVLGLLDDLDLTVRRGRLDHGDAVLLYTDGIIEEPCRDLDLGIDRMMGEAESVLRGSFVGAAGRLTTTLGSRDDDRAMVVVRRT
>NZ_CP040695.2|WP_138875268.1|1046358_1047795_+|trigger-factor
MKSAVETLSPTRVKLTVEVPFEELKPNLDKAYQQIAKQINVPGFRRGKVPPMVIDRQVGRGAVLEQAINDTLPQKYVEALEANELTPLAQPEIEGLEIADDEGFGFTAEVDVKPTITVPDYTGITASVDDVEVTDSDVDEQVDALRERFATLTDVERPAADGDFVVLDLKATQDGEVVEGAEVTGMSYQVGRGGMIEGLDEALVGLTPGEDKIFDSELVGGDLLGEQVQVAVSISQVQEQELPEYDDEFAQLASEFDTVEELTADVRERLGRGKRLEQAAAARDAVLEALLEQVEIPLPESIVTDELNSRRQSIEQQLAMAGITMEKYLEDESQTVEEFEADLDRRVRDAVAAQFLLDEIAKKEEFGIDQAELSQHLVRRAQQSGQDPQQFANHMFEHNHIPDLVQEILRGKALQTIVDAAVVTDASGNAVELKNLRPDGTIGDPEAEAAEAAEAEADVEEADAEGDAESDDDAAKDA
>NZ_CP040695.2|WP_148240395.1|1047884_1049609_+|protein-kinase
MVSGGMGTSDGSDAAWRPPAAGPATVEELDGYTDLTEVGRGGDSVVYRARQESVGRDVAIKVLSIDTTSDPARSVRFKREIDITVQLGRQHPNIVTVLAVGTTASGKPAVVMDFFEGGTLHDRLKAHGPLPPEEVGRIGEVLADALSFAHERGVLHRDVKPQNVLVLPTSWVLADFGIARLVDSEHTSSAETFTYRHAAPQILDGHPPTPLDDVWSLGSTLYTLLDGRPPFASDDPDEDSALAYLRRARTEPHRPLQVPGAERLAPIIDRCLSKDVAGRWGSAAALHDALHALRGSAWEPAGPTTPPLLAKAAPPRTAGDAAESPTPTPTPTLHASAPAPISPAPISPAPLSPSPARGAEPAEPSPVAISAVSHVVRVADAAPTGTGFPDTTGAAPGPSEPTPEAPEEEKAPRRRLPIVLGVAALVIGLLLGLLGAVLRGRDDDETPVRAAVTPDGSAVAPPSVGGTVTSRPDTDLAVVLQSLEYDGVTLRATWTDPADGEGSFALLATDPSFPNGRVIATFPAGQTSGEAAVRGLPPGRTCFFMGVFLVDGTYGLNNRQSRCEEVVAGGGFAS
>NZ_CP040695.2|WP_148240396.1|1049676_1051782_-|hypothetical-protein
MRDGTPSPATRALQLAWPVALVVLGAMVLATAWHRWTISLLFAAVAAVPLLALRGLLRAGLSRWFATSLLLLLTVMAAYLATTGADLTLEQTVQDVVPRLLTSPQPYAVQADLLAGPLLLTALVSLLVGLRVDSRLRVEAVLGAAVLYVAGALLTAGSADPWGLVAVLTLIVAVLGWVFLDEHSEPVRQRLSMAGPVAVVGVGALAALATLPVGQAFEPRDLVAPPTYEVVASNPLTQLGAWANNPTDELLEVRGDEGPLRLVVLDDYDGLQWTAATRYEALPTDGRTGLEPGIYPRSTTVQVSFSRLGGSWLPSPGLPSSVALADALVDPGTGTLYSGVDTAGLVYEVTGAFDDPPQAALDAAELPEDGLEPMTALPPLSNALADLAARVGEGADTAYQRAARIETFVRSSYELSTTAISGSALWRIERFLLSDRTQSGGGVGTSEQFASAFAVLARANGLPTRVVVGFRPGEVQDDGTRVIRGEDAFAWAEVYFRDLGWVPFSPTPDDDTFRRPRPVEAEEPRLPEPADTGAPVPTPSGGEPATDAPAPVDDETASAPTSTSGAAPDPYLVAAAALAALLLGLVALRGGRRLRHARQGPPGAWAEVVDALRLAGIRPAPHQPADLVAADADARLGTTAAVPIAARAEAVAFGPPGGRDAGSAADARGRLGEVRRAARRTVPAWRRWWWHLDPRVLGRRR
>NZ_CP040695.2|WP_138875270.1|1051778_1052972_-|DUF58-domain-containing-protein
MLPVWSSTTGRGRAMLALGLVLLVAGTAWGYLLVAGLGGCLVLLVLVEVTAVLSARRVAVERTIEPAVVVRQGRCEGTIAVRGRRRRGLVRLDVADRVQGTLVPVALPDRADEVEEADRVAGEPTVRVRYQVPTPRRGLVDVGPVQVRMAGLTGMAARSAEHGRVDQVRVLPRRIPLGAMMAGTRRSLSGGDDAHELGGTDLVGLHEYAMGDDLRRLHWATSARTGTLMVREDAEPSEAHVTVLLDDRASSYLGDENLFEEAVELAAALCRSGIEAGSPVRLHTTSDRHEVRVPGSVGGRPRREHQELDWVLAEIDLTGPSTQVELHGRDLDVAVGVTGPGADLHLLGLALGTAPTRVLAVVDPAPLVGAHQEAGLLVLRGATSVTLALGWDEAVER
>NZ_CP040695.2|WP_137295680.1|1052995_1053985_-|MoxR-family-ATPase
MTALINPAAPGEQEIAGFGRLHQALGDAVETAVHGKRAVVDLALVATFAGGHILLEDVPGTGKTTLARAISRAMGGQDGRIQFTPDLLPSDVTGTTVFDPRDGQIRFRQGPVFANVVLADEINRAAAKTQSALLEVMQERTVTVDGVAHPVPTPFVVIATQNPIDLDGTYRLPEAQLDRFLIRTSLGYPDAEHEIEVLRPGSTAGRVDDVPTVTTPDEIAAVTAQLSRLHVADPILRYVREIGVGIRRDPRVRIGVSTRGLKALVGCLQVYAAARGRHYVVPSDVQRLAEPVLAHRTVLGRDAILAGHTSQDVVHEVLDVVNPPQPDAG

Crispr_ID: NZ_CP040695_8

• CRISPR_ID: NZ_CP040695_8
• CRISPR_location: 1171494-1171626
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_8

Consensus_repeat	Method
CGGTGGTTGAGTCGGCGTCCTCGGCCCGGGGGTTTCGTCGGCGCTCGC	CRISPRCasFinder

spacers of NZ_CP040695_8

>8.1|1171542|37|NZ_CP040695|CRISPRCasFinder
CGGGGCTCGCTTGCTCAACCTCCGGTGGGAGCGAGGG

CRISPR arrays and Neighbor proteins around NZ_CP040695_8

CRISPR arrays

The CRISPR arrays of NZ_CP040695_8

>merge|NZ_CP040695|8|1171494-1171626|CRISPRCasFinder
CGGTGGTTGAGTCGGCGTCCTCGGCCCGGGGGTTTCGTCGGCGCTCGCCGGGGCTCGCTTGCTCAACCTCCGGTGGGAGCGAGGGCGGTGGTTGAGTCGGCGTCCTCGGCCGGGGGTTTCGTCGGCGCTCGCT

>NZ_CP040695|8|8|1171494-1171626|CRISPRCasFinder
CGGTGGTTGAGTCGGCGTCCTCGGCCCGGGGGTTTCGTCGGCGCTCGC	CGGGGCTCGCTTGCTCAACCTCCGGTGGGAGCGAGGG
CGGTGGTTGAGTCGGCGTCCTCGGCCGGGGGTTTCGTCGGCGCTCGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_148240967.1|1171821_1172208_-|hypothetical-protein	unknown	unknown	gnl|CDD|225557
NZ_CP040695.2|WP_148240408.1|1172308_1173697_+|magnesium-chelatase	unknown	unknown	gnl|CDD|224160
NZ_CP040695.2|WP_137294176.1|1166803_1167991_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224050
NZ_CP040695.2|WP_148240409.1|1179516_1180158_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137294179.1|1163572_1164601_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238874
NZ_CP040695.2|WP_138875320.1|1175847_1176279_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137294167.1|1178032_1178671_+|YigZ-family-protein	unknown	unknown	gnl|CDD|224653
NZ_CP040695.2|WP_138875318.1|1169845_1170637_+|aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|131620
NZ_CP040695.2|WP_138877080.1|1168094_1168802_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224095
NZ_CP040695.2|WP_137294181.1|1161826_1162459_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP040695.2|WP_138875321.1|1176339_1177221_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238564
NZ_CP040695.2|WP_137294178.1|1164645_1166052_+|cystathionine-beta-synthase	unknown	unknown	gnl|CDD|273464
NZ_CP040695.2|WP_138875322.1|1177256_1178036_+|TSUP-family-transporter	unknown	unknown	gnl|CDD|182593
NZ_CP040695.2|WP_138875316.1|1162613_1163471_+|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|378959
NZ_CP040695.2|WP_138877079.1|1161139_1161679_+|peptide-deformylase	unknown	unknown	gnl|CDD|366575
NZ_CP040695.2|WP_137294177.1|1166165_1166807_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224095
NZ_CP040695.2|WP_137294171.1|1173689_1175744_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|227204
NZ_CP040695.2|WP_137294175.1|1168801_1169794_+|glycine-betaine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270329
NZ_CP040695.2|WP_138877082.1|1180297_1180777_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP040695.2|WP_138875323.1|1178675_1179476_+|VOC-family-protein	unknown	unknown	gnl|CDD|380093

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_148240967.1|1171821_1172208_-|hypothetical-protein	gnl|CDD|225557	COG3012, COG3012, Uncharacterized protein conserved in bacteria [Function unknown].	4.45361e-36
NZ_CP040695.2|WP_148240408.1|1172308_1173697_+|magnesium-chelatase	gnl|CDD|224160	COG1239, ChlI, Mg-chelatase subunit ChlI [Coenzyme metabolism].	5.41171e-106
NZ_CP040695.2|WP_137294176.1|1166803_1167991_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	3.10324e-145
NZ_CP040695.2|WP_137294179.1|1163572_1164601_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	4.30358e-43
NZ_CP040695.2|WP_137294167.1|1178032_1178671_+|YigZ-family-protein	gnl|CDD|224653	COG1739, COG1739, Uncharacterized conserved protein [Function unknown].	9.85158e-60
NZ_CP040695.2|WP_138875318.1|1169845_1170637_+|aminoglycoside-phosphotransferase	gnl|CDD|131620	TIGR02569, conserved_hypothetical_protein, TIGR02569 family protein. This protein family is found, so far, only in Actinobacteria, including as least five species of Mycobacterium, three of Corynebacterium, and Nocardia farcinica, always in a single copy per genome. The function is unknown. [Hypothetical proteins, Conserved].	4.18485e-21
NZ_CP040695.2|WP_138877080.1|1168094_1168802_+|ABC-transporter-permease-subunit	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.4435e-54
NZ_CP040695.2|WP_137294181.1|1161826_1162459_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.63803e-17
NZ_CP040695.2|WP_138875321.1|1176339_1177221_-|ABC-transporter-substrate-binding-protein	gnl|CDD|238564	cd01144, BtuF, Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	5.39843e-61
NZ_CP040695.2|WP_137294178.1|1164645_1166052_+|cystathionine-beta-synthase	gnl|CDD|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	0
NZ_CP040695.2|WP_138875322.1|1177256_1178036_+|TSUP-family-transporter	gnl|CDD|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	1.46726e-38
NZ_CP040695.2|WP_138875316.1|1162613_1163471_+|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|378959	pfam12811, BaxI_1, Bax inhibitor 1 like. The Bax-inhibitor-1 region of the receptor molecules is conserved from bacteria to humans.	1.82975e-71
NZ_CP040695.2|WP_138877079.1|1161139_1161679_+|peptide-deformylase	gnl|CDD|366575	pfam01327, Pep_deformylase, Polypeptide deformylase.	1.04416e-44
NZ_CP040695.2|WP_137294177.1|1166165_1166807_+|ABC-transporter-permease	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.30962e-49
NZ_CP040695.2|WP_137294171.1|1173689_1175744_+|VWA-domain-containing-protein	gnl|CDD|227204	COG4867, COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain [General function prediction only].	0
NZ_CP040695.2|WP_137294175.1|1168801_1169794_+|glycine-betaine-ABC-transporter-substrate-binding-protein	gnl|CDD|270329	cd13611, PBP2_YehZ, Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	7.67931e-147
NZ_CP040695.2|WP_138877082.1|1180297_1180777_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.06367e-12
NZ_CP040695.2|WP_138875323.1|1178675_1179476_+|VOC-family-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.56291e-16

Protein sequences

>NZ_CP040695.2|WP_138875318.1|1169845_1170637_+|aminoglycoside-phosphotransferase
MSSPPTEVLDLFAVPHVVEPLPGGSGRSVRAGDLVLSPGRDEATAAWLNPVLARLAVRLDESPTRRPRDLRIAMPVPARDGAWVVAGWGASRYEPGTTGCDDLDVTLAAGRLLHAELASVVGRPPAALAARTDRAALAERAAFGAVGELSGPVAGRVAPLLDDTPLGPDQLVHTALHGNVLLDAAGAPVVLDVTPAWRPTLWAEALAVLDAVLAADAPLSVLQRWTTARERQAMLRALLFRVLANDVQALAPYAPVLAVLTGG
>NZ_CP040695.2|WP_137294175.1|1168801_1169794_+|glycine-betaine-ABC-transporter-substrate-binding-protein
MRTRLRNVLAAAAAGAVVTTTAGCGLGTAGGFVPDAQLAGPLADAPRLDGVPITVGSKNFSENILLGKMALILFKAAGADTEDLTNIPGSAPARQAHVEGDVDAMWEYTGTGWLVYLGHPKPVQGKEEQYDAVREEDLEVNGLDWLPPAPMNNTYAFAVTKASQEKYGITKLSEIKQKVPKAERTFCVESEFRNRADGLEGMLKAYGIPLGNEVPSGNLQTYQTGAIYDATASGQCLLGEVFTTDGRILALDLQVLEDDKAYFPNYNVSLVVRSGLLEDHPEIEDLMAPVTEKLTDEVMKELNAEIDVDGREPEDVAFDWLKSEGFVSDP
>NZ_CP040695.2|WP_138877080.1|1168094_1168802_+|ABC-transporter-permease-subunit
MLTVPPALVLIAFAAFVVWRQSAEFTETELRQLAWTEIRSLLWQHVKLTVTSSVLVVAIAVPLGIALTRSGLRKFSPLVVGFANIGQGAPSIGLIVLLAIWLGYGFWTSVLALTLYGLLPVLRNTIVGLDGVDPTLVEAGRGLGMSAGSVLLRVELPLALSVIMAGVRTSLVLVVGTATLATFINGGGLGAIIQTGISLFLPKLIVAGALLVALLALFVEWLGRVLEFLARPKGV
>NZ_CP040695.2|WP_137294176.1|1166803_1167991_+|ABC-transporter-ATP-binding-protein
MTTDLTKESEPGPAPEQGTADISGAEIVLEDVVKKYPGQKNAAVESLSLTIPAGEIVMFIGPSGCGKTTSLKMINRLIEPTSGTIRIGGEDIRGQSENELRRKIGYVIQGGSLFPHMTVAKNIALVPKLLGWDAKRISTRVEELLELVGLDPSRYRDRYPRELSGGQQQRVGVARGLAADPPVILMDEPFGAVDPITRQRLQDEMLSIQRELRKTIVCVTHDIDEAIKLGDRILILQEGAQVAQYDTPEVILGAPANEFVEDFVGAGSSLKQLSLTRVSEVELRRPTTAVVGEQVAEVKRRAEANGDRSVIVLDSRNRPVGWPWLRQLKGDVVLEPTEDLVNLDQRATLNDALDTMLSSSHGGAVVTGDRDQYLGVVVFDAVTDHIRSLEEQARG
>NZ_CP040695.2|WP_137294177.1|1166165_1166807_+|ABC-transporter-permease
MWDFIVERREALLYNTFQHANLVVQAVLVATVVAVLLAVLITRVPRLEGPANALSAIGLTIPSFALVSLLLTFFSFGSLPAFIAVAFYAVLPVLRNAVVGLQGVDATLLESARGMGMSELTTLLRVRLPLAWPVILAGVRVSMQMSMGVAAIAAYVGGPGLGTYILKGLTQIGGANAINYALVGTIGVVVVALLADLVLLLLGRATISKGVRA
>NZ_CP040695.2|WP_137294178.1|1164645_1166052_+|cystathionine-beta-synthase
MEYANSVLDLIGNTPLVRLSRTLDLPGAGDGSAGGPLVLAKVEYLNPGGSVKDRIATRMIEAAEASGALQPGGTIVEPTSGNTGVGLAMVAQQKGYSCVFVCPDKVSEDKRNVLRAYGAEVVVCPTAVAPEHPDSYYNVSDRLASQPGAWKPDQYSNPHNPRSHYETTGPEIWAQTEGRITHFVAGMGTGGTISGVGRYLKEQNPDVKVIGADPAGSVYSGGTGRPYLVEGVGEDFWPETYDRGVADRVIEVSDADSFAFTRRLAREEALLVGGSCGMAAHAARTLAHELAGTPEGEDAVIVVILPDSGRGYLTKIFNDEWLAQYGFSSGNQVPSQTVGEVLRGKSGRLPELVHTHPSETVAEAVAILQEYGVSQIPVVRAEPPIVAAEVAGSVSDRTLLDALFAGHARLTDPVEQHMSPALPTIGSGEDADAAVALLESADAVLVHEDGKPVGVLTRQDLLAHLARA
>NZ_CP040695.2|WP_137294179.1|1163572_1164601_-|SGNH/GDSL-hydrolase-family-protein
MGKAGAARKLASAAAFGGGGLSLLGAGLYGVLTAEAKLARKTIGEASSDPTPDATGWYGRGRPGPALKIALFGDSSAAGYGVDRVEEVPGALLGSGVAEQGDRRVYLREFCKVGAVSADLAGQIDRALPIEPHLAVILVGANDVTHVTMPSQSVRHLSEGVRRLREAGVHVVVGTCPDLGTIKPIAPPLKQVARAWSRRLAAAQTIAVIKEGGRTVSLGSVLGPEFLAAPALLFGPDQFHPSAEGYRALARILLPSVLAGLGLAPDEEARPETHRGEGVMPVARAAIQAVNEPGTELDGTEVGGNRAGVRGLWVELRHRRRRPQTRGEAPQDAEHGAPSSDR
>NZ_CP040695.2|WP_138875316.1|1162613_1163471_+|Bax-inhibitor-1/YccA-family-protein
MQSNNPVFRRSEEFNRAGGQTQQTYAQQSPSTWQTSPAGGAFGYDDVRQTPANRGGAMSIDSVVQKTAITLGVVILTALATWILTPDIDGFTTSSELGTIYGAAMFGALGAFALSMVNSFKRVVSPALVLAFAALEGVALGAISKAFDAQFGDGVVSGAVIGTFAAFAGTLTAYKVFNIQVGAKFKMFVMAAVFGMIGLSLMELVLSLFGAQIGLFGVSGLGMVTAFAGLVLGVFMLIMDFDFVEQGIRNQLPERESWRAAFAMTVSLVWIYTNLLRILAFFSQD
>NZ_CP040695.2|WP_137294181.1|1161826_1162459_+|class-I-SAM-dependent-methyltransferase
MTDLRDMFTREFWDERYASSHRIWSGEPNRRLVDQVEALAPGTALDVGCGEGADAVWLAAHGWTVTGVDVSGVALERAEEHAREAGVGERTSWLRADVFAGDALPVGFDLVSAAYVHVPPEDFAAVYTALIASVAPGGSLVVLAHHPDDVHTGLRNTELSHLLFGPDAVTSLLDPAQWDVVAAETPTRPITHDGRELEVTDTVVRAVRRA
>NZ_CP040695.2|WP_138877079.1|1161139_1161679_+|peptide-deformylase
MRAWTEAELGVEGRVLDVVRAPAAVLSTPGGAVDPTDPAVVQLAADLVATMRVSPGCVGLAAPQVGLAVTVFCVDVSEHPKTREHHGTFVLCNAEVVESSRNDRGREGCMSVPDLTGDVKRASRVVVRGALPGTGEVVEVAATAFEARALQHEIDHCAGLLFLDRVAGAHAVYARQTYL
>NZ_CP040695.2|WP_148240967.1|1171821_1172208_-|hypothetical-protein
MGPVSLRPDCPCGTGATYDACCGRLHRGAAQAGTPEELMRSRYAAYAVGDGGYVWRTWHPRTRPLDVNPDPTLRWTGLVVEDASGDEVEFTATFEQDGRPGRLHERSRFEHRAGRWFYLDALPDPTRG
>NZ_CP040695.2|WP_148240408.1|1172308_1173697_+|magnesium-chelatase
MVTRPTISTLGELRAAGHVQKSLRTEIRDNLLAKLAAGEDPWPGLHGFENTVVPQLERALIAGHDIVLLGERGQGKTRLLRTMVGLLDEWTPVLAGSDLGEHPFEPITHESRRRATEEGDRLPVEWRHRDERYAEKLATPDTSVADLIGDVDPMKVAEGRSLGDPETIHFGLIPRSHRGIVAINELPDLAERIQVAMLNVMEERDIQIRGYVVRLPLDVLVVASANPEDYTNRGRIITPLKDRFGAEIRTHYPTELDAEIAVIRQEADLVADVPDYLVEILARFTRQLRESSSVDQRSGVSARFAIAGAETIAAAALHRATVQHEDDAVARVVDLETAVDVLGGKIEFETGEEGREDEVLTHLLRTATAETVRAHFRGLDLGVLVAAIENGAMVTTGEQVTARDFLTGLPVLGESELYDDICDRLGASDDGTRAGAIELALEGLYLARKIGKDSDGSETVYG
>NZ_CP040695.2|WP_137294171.1|1173689_1175744_+|VWA-domain-containing-protein
MARTRSNRFKKYDGGDPLAPPVDLAEALDAIGEDVMAGYSPERAMREFLRRGGQDQRGLDDLARRVAERRRELLEQHDLDGTLQEVRELLDNAVLEERKQLARDAMMDDGDRALREMQMDNLPPNTAAAVSELGGYDWQSSQAREDFEKIKDLLGRELLDQRFAGMKQALENASEADRAAVQEMLGDLNELLDKHRRGEDTQQDFDDFMAEHGEYFPEGPENLEELLDTMAQRAAAAQRMLNSMSPEQRQELMELSAQAFGSPELMDQLAQLDSNLQSLRPGEDWGGSEQMGEGGEGVGLGDGTGVFQDLADLDQLSEQLAQSYGGARLDDLDLDALSRQLGDEAAVDARTLQQLEKALRDGGTLRRGSDGQLSLTPKAMRQLGKALLRDVAQKLSGRQGQRDLDRAGASGERSGATREWQFGDTEPWDIPRSVLNGVRRRATDPTDRRALAIDDVEVQETEARTQAAVALLVDTSFSMAMDGRWVPMKRTALALHTLIRTRFRGDHLQLIGFGRQAEVMDIEQLTALDAMWDKGTNLHHALLLANRHFRKHPNAQPVLLVVTDGEPTSHLEASGEVYFSYPPHPMTIAHAVRELDNSRRMGAQTTFFRLGDDPGLARFIEQMAQRVDGRVVSPELDDLGAAVVGSYLGSRDAGRPGGSGGIMSGLRSHYGDWLGGRGSWVGDD
>NZ_CP040695.2|WP_138875320.1|1175847_1176279_-|hypothetical-protein
MRMFRTIAAVAALVMAATMTSLVASPSTAAAPSADRFSASSAAPAAKAALPRHKMKSVRGVETGGGKFAALGKIPTFKNKKVLLRKAVSKNKPFRAYKSARTNGKGKFRIAFDGRIGNCFEVVAAKTPRNARTAKVIGCIIPG
>NZ_CP040695.2|WP_138875321.1|1176339_1177221_-|ABC-transporter-substrate-binding-protein
MRIVSLLPSTTEILFAVGAGDDVVGVTFECNHPPEARRRRIVSTSSMPEGLTPAAIDAHVAAAVARGEDLYRLDAGALADLDADLVVTQDLCAVCAIDVTLVDDALAHLGCTADVLTLDPHTLDDVLASVLRLGEATGRLPAAQGLVADLRRRLDVVREGVARAADRPRVVVLEWTDPPYAPGHWIPEMVTLAGGECVLGVAGEKSTRVPWSAVLDARPDVVVVAPCGYDRAGAQAQADALVAAGTLPDGVLVHAVDADAMWARPGPRLVDGIEELAGVLRRHRDEARGTQEV
>NZ_CP040695.2|WP_138875322.1|1177256_1178036_+|TSUP-family-transporter
MSEPTLTVLALLALAGLVAGYVDAVVGGGGLVQLPALLLGLPGASPVEVLATNKLGSICGTSVSSITYYRRVRPDPRTFLPLMGFAFTGSVLGAFVASHIPRSAFDPIVLVVLVLVGTYVVVKPDLGDETTLRFGGHRHTLMAVLTGLGVGFYDGALGPGTGSFFVFLLVGLLGYNFLEASAKARLANWATNLAALCVFVPQGAVLWHVGLTLGAANLVGGYLGARTAIARGAGFVRAFFIVVVAGFAVRIGGGVVGLW
>NZ_CP040695.2|WP_137294167.1|1178032_1178671_+|YigZ-family-protein
MSAGSYLTIARDTQAETEARRSRFLCTLERVEDEDAARAVVDRLRRAHHDARHHCSAFVLGPPGGGQVVRSSDDGEPSGTAGAPMLEVLRGHGLADVVAVVTRWFGGTLLGAGGLVRAYGDAVRAAVDEAGTLRRGLLRELALEVGHDVAGRVESDLRGRGVVVLDTAYGAAVTLRLGVPPAEEDAVHALVAELSGGAAEALVVGERWVDLR
>NZ_CP040695.2|WP_138875323.1|1178675_1179476_+|VOC-family-protein
MTTDATSAATPTGAGPTWLTAFLDLAPDDFERGVVFWAGVTGCEVSPSRGRHDEFATLVPADGDAHLRLQCLRAGRSDVHLDLHVADPWAAAERAVRLGASVVADRGYVVLESLAGLTFCLVPEPGSARPVPATPGSWPGGRSQVDQVCLDVGPAAHDAECAFWQELTGFDPTPASGAEFRRLDAPGMPLRLLLQRLDEERPPGIHLDLAADDRAAEVERHLALGATPGPTPSGPDRGFTVLVDPAGSRYCITDRVPGTRGAGSGT
>NZ_CP040695.2|WP_148240409.1|1179516_1180158_+|hypothetical-protein
MTLLQPGPRTSSPLRADDRSAASALSLAVALGIALGVVDLLLQTTLPYPWANLANSSAVWAVAAFALARVLAPTAAVGAAAGAVFLVVAVEAYYVAAIAVDLASPSSLVAASSLAWAFFGVVAGVGFGVAGVWSRAGDTWPAAAGLGLASAVLVAEAWLRLDTPGTAVLTGTAGVLVLASTVHRPVLLRRAALCAGALVVPCHLAFGVAGFGG
>NZ_CP040695.2|WP_138877082.1|1180297_1180777_+|GNAT-family-N-acetyltransferase
MTPDDWPRVWPFFRDVVAAGETYAYPLDLTSEQARDLWTMRPPGLTVVLEDDDEPGRLLGSATMGQNRPGRGAHVGTASFMVAPDARGRGVGRRLGEHVVAWHREQGFAAIQFNAVVETNTVAVRLWESLGFRVIGTVPAAFDSRAHGRVGLHVMHLEL

Crispr_ID: NZ_CP040695_9

• CRISPR_ID: NZ_CP040695_9
• CRISPR_location: 1587927-1588040
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_9

Consensus_repeat	Method
TGACCCGTCGCTGATCACTGACGGGTCG	CRISPRCasFinder

spacers of NZ_CP040695_9

>9.1|1587955|58|NZ_CP040695|CRISPRCasFinder
ACGAGAAACCTCCGCTGACCCGTCGCTGATCACTGACGGGTCAGCGAGCAATCCCTGC

CRISPR arrays and Neighbor proteins around NZ_CP040695_9

CRISPR arrays

The CRISPR arrays of NZ_CP040695_9

>merge|NZ_CP040695|9|1587927-1588040|CRISPRCasFinder
TGACCCGTCGCTGATCACTGACGGGTCGACGAGAAACCTCCGCTGACCCGTCGCTGATCACTGACGGGTCAGCGAGCAATCCCTGCTGACCCGTCGCTGATCACTGACGGGTCG

>NZ_CP040695|9|9|1587927-1588040|CRISPRCasFinder
TGACCCGTCGCTGATCACTGACGGGTCG	ACGAGAAACCTCCGCTGACCCGTCGCTGATCACTGACGGGTCAGCGAGCAATCCCTGC
TGACCCGTCGCTGATCACTGACGGGTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138875516.1|1573364_1574033_-|response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP040695.2|WP_138875518.1|1583863_1585060_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379062
NZ_CP040695.2|WP_148240484.1|1577281_1580542_+|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|223288
NZ_CP040695.2|WP_138875526.1|1593156_1593951_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|181723
NZ_CP040695.2|WP_138875522.1|1588434_1590489_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|223288
NZ_CP040695.2|WP_138875515.1|1570013_1573310_+|peptidase-M14	unknown	unknown	gnl|CDD|349463
NZ_CP040695.2|WP_148240483.1|1575708_1577217_+|potassium/proton-antiporter	unknown	unknown	gnl|CDD|235410
NZ_CP040695.2|WP_138875520.1|1586171_1586909_-|purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|180275
NZ_CP040695.2|WP_138875525.1|1591949_1592711_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138877102.1|1580610_1583814_+|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|223288
NZ_CP040695.2|WP_137295422.1|1575161_1575722_+|hypothetical-protein	unknown	unknown	gnl|CDD|366488
NZ_CP040695.2|WP_138875527.1|1594286_1595363_+|PHP-domain-containing-protein	unknown	unknown	gnl|CDD|236135
NZ_CP040695.2|WP_137295431.1|1591079_1591415_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP040695.2|WP_138875524.1|1591411_1591639_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138875519.1|1585072_1586143_-|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224983
NZ_CP040695.2|WP_137295421.1|1574029_1574971_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP040695.2|WP_148240485.1|1595837_1596437_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|239646
NZ_CP040695.2|WP_138875523.1|1590626_1590875_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137295436.1|1595373_1595907_+|M48-family-metallopeptidase	unknown	unknown	gnl|CDD|320703
NZ_CP040695.2|WP_137295428.1|1588084_1588354_-|mycoredoxin	unknown	unknown	gnl|CDD|131255

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138875516.1|1573364_1574033_-|response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.21542e-68
NZ_CP040695.2|WP_138875518.1|1583863_1585060_+|AAA-family-ATPase	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.14735e-07
NZ_CP040695.2|WP_148240484.1|1577281_1580542_+|UvrD-helicase-domain-containing-protein	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.20468e-100
NZ_CP040695.2|WP_138875526.1|1593156_1593951_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|181723	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein.	1.86173e-66
NZ_CP040695.2|WP_138875522.1|1588434_1590489_+|AAA-family-ATPase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.93998e-89
NZ_CP040695.2|WP_138875515.1|1570013_1573310_+|peptidase-M14	gnl|CDD|349463	cd06244, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	8.40257e-43
NZ_CP040695.2|WP_148240483.1|1575708_1577217_+|potassium/proton-antiporter	gnl|CDD|235410	PRK05326, PRK05326, potassium/proton antiporter.	0
NZ_CP040695.2|WP_138875520.1|1586171_1586909_-|purine-nucleoside-phosphorylase	gnl|CDD|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	7.81293e-142
NZ_CP040695.2|WP_138877102.1|1580610_1583814_+|UvrD-helicase-domain-containing-protein	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	4.36868e-91
NZ_CP040695.2|WP_137295422.1|1575161_1575722_+|hypothetical-protein	gnl|CDD|366488	pfam01145, Band_7, SPFH domain / Band 7 family. This family has been called SPFH, Band 7 or PHB domain. Recent phylogenetic analysis has shown this domain to be a slipin or Stomatin-like integral membrane domain conserved from protozoa to mammals.	0.000110247
NZ_CP040695.2|WP_138875527.1|1594286_1595363_+|PHP-domain-containing-protein	gnl|CDD|236135	PRK07945, PRK07945, PHP domain-containing protein.	0
NZ_CP040695.2|WP_137295431.1|1591079_1591415_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.34571e-13
NZ_CP040695.2|WP_138875519.1|1585072_1586143_-|NAD(P)-binding-domain-containing-protein	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.04806e-34
NZ_CP040695.2|WP_137295421.1|1574029_1574971_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.40952e-55
NZ_CP040695.2|WP_148240485.1|1595837_1596437_-|NUDIX-domain-containing-protein	gnl|CDD|239646	cd03674, Nudix_Hydrolase_1, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, U=I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.11709e-32
NZ_CP040695.2|WP_137295436.1|1595373_1595907_+|M48-family-metallopeptidase	gnl|CDD|320703	cd07344, M48_yhfN_like, Peptidase M48 YhfN-like, a novel minigluzincin. M48 YhfN-like protease is considered as a CaaX prenyl protease 1 homolog, with most of the sequences in this family as yet uncharacterized. It contains the zinc metalloprotease motif (HEXXH), likely exposed on the cytoplasmic side. It is probably associated with the endoplasmic reticulum (ER), regardless of whether its genes possess the conventional signal motif (KKXX) in the C-terminal. Proteins in this family proteolytically remove the C-terminal three residues of farnesylated proteins. This novel family of related proteins consist of the soluble minimal scaffold similar to the catalytic domains of the integral-membrane metallopeptidase M48 and M56, thus called minigluzincins.	7.91892e-24
NZ_CP040695.2|WP_137295428.1|1588084_1588354_-|mycoredoxin	gnl|CDD|131255	TIGR02200, conserved_hypothetical_protein, Glutaredoxin-like protein. This family of glutaredoxin-like proteins is limited to the Actinobacteria and contains the conserved CxxC motif.	5.8598e-30

Protein sequences

>NZ_CP040695.2|WP_138875520.1|1586171_1586909_-|purine-nucleoside-phosphorylase
MSTHIGAAPGDIAPVVLMPGDPLRARWIAETFLDDVACYSEVRGMYGYTGTWRGHHVSVQGSGMGQPSCAIYATELIREYDVQTIVRVGSCGALTERLGIRDLVIASGACTDSSMNRITFEGLDYAPVADFGLLRDAAAAAPEAHVGLVFSSDSFYASRPELATRMVDHGVLAVEMEAAALYTIAARHGRRALAVCTVSDHVVTGEETTAHEREQTFGRMVEVALTAALGSGVAPGAGGEGGHGE
>NZ_CP040695.2|WP_138875519.1|1585072_1586143_-|NAD(P)-binding-domain-containing-protein
MEVYDSVVIGAGQAGLSASYHLQRRDVRHVVLDADAAPGGAWQHRWDSLSMADVHGVAALPDSARPEPDGGERANVAVPAYFATYEREHHLPVVRPVRVDRVDDTDEGLLVVRAGERTWTTRTVVNATGTWSQPFVPHYPGASGFAGPQWHTADYPGAEAFRGLRTVVVGGGASAVQLLGEVALVTDTVWVTRRPPVWRTDDFTPEVGRAVVALVEERVRQGLPPASVVSVTGLALREQERAAEAVGAYVRRPMFSSVEPDGVRWPDSFEPAQAILWATGFRPAVGHLAPLHLRSPLGGIRLEGTTAVADPRVQLVGYGPSASTIGANRAGRVAARGVVAALASDAGTLDADALGA
>NZ_CP040695.2|WP_138875518.1|1583863_1585060_+|AAA-family-ATPase
MTTPPATEALPDPYTPGQVPRVLAGRAVELGRIRDRLGRVASFGELAGPLLVFHAPRGLGKTSLLRTAEREAAAIGFASAWLACSRERPFLPELVRSVERALDRVDLRVESRRRWRDRLTSLSVELGVLGVSVGGEVDATGDRSPDAGAAPIGALEDLLHEAARAVRDRGGAGLVVFIDELHAASADDLATLLNAVQNLDGDRDDNPLTVVTAGLPVTPEAIIRAATFGERSAFVPLDVLSDDDARQLLVLPSDALGVTWEADALEAVVRRVGGHPYLLQLAGSCTWQALRPRAGAVVDEAAVDAGLPAAEVQLTAMHAARWGSATELERTFISAMASVGPGNVTRARIAAAMGVDSRSISVPRERLIEKGIIEPVGHGLVRFTMPGFDAWVRARGQD
>NZ_CP040695.2|WP_138877102.1|1580610_1583814_+|UvrD-helicase-domain-containing-protein
MVVDTPERLRDLLGESWTFSEAQFTAITAPLEPAVVIAGAGSGKTSVMAARVVWLVATGQVAPAEVLGLTFTTKATAELETRIRESLRGAGLLPERSAPRDDDDEEVEEPTVSTYHSYASALLSEHGLRIGHEPDTRLITDASRYQLAARAVQRYTAPVAHLTDSPLHVVRYLLALDAEMSEHLVSPAQVRAHDAAARPLFEAGMLTEHRSTYRAKNEKAIATIDARAELLGLVEAYRGLKAHLGLMDFSDQIALAARLAETCPEVGEVERGKYRVVLLDEYQDTSVAQALMLSRLFSGAEGQPGRGHAVTAVGDPNQAIYGWRGASVSNILEFGQDFPAVDGATTTYPLVVNRRSDRRILATANHLAADLYALRSDLLPLEPTPGAAEGDVRAIVHETSLDELDWLAEQVLATHAELAAAREGPVWKEIGVLTRDNATAAAAFDALTAREVPVEIVGLKGLLRLPEVAEVVATLTLVQDVTANAALLTLLAGPRWAIGPRDLALLGRRAGELAGARTGAETFPDVHEQLVAAVEGADPTEIPSLCDALEDLGDAGYSAEARERFVLLAAELRRLRSAIGEPILDLVRRIIDTTGIDVELASSVSPAAAARRDNLDLFVQAVAEFQAVDGQVTLAALLAWLEAEDEHGQGLDVATPSEADSVKLLTVHRAKGLEWDAVFLVGVTDKKFPTSRGRSSWLTVSSVMPTALRGDARDLPQLAGHTPADIADVARRAKAHDALEELRLGYVAWTRARHLLWVSAWRWAPHLKTGNGPSPYLVRTREAMAGWGGEPDAWGEVVAKGEVSPFAGRVVDQPWPISHHTPEVERRLDAAARVRAADPDAGDDLEDVLELDRVQQWDDEIERLLDEAARERASEIVVPLPSSLSATSVARLRDDPDAFARDLARPMPRAPSPAARFGTRFHAWVEARFGQQLLLDPDDLPGRADAGIEDDADLQELIAAFERGPFAERPPLVVEPSFALVLAGQVVRGRIDAVYAEGEDFLVVDWKTGRGGGTDPLQLALYRLAWAELRGVDVERVRAAFYHVRSGRLVEPADLPGRDELTRLLDL
>NZ_CP040695.2|WP_148240484.1|1577281_1580542_+|UvrD-helicase-domain-containing-protein
MTTSAPTYRLVREHVAVDVPVLDPQQQAVVEHREGPLLVLAGPGTGKTTTLVEAIVDRIEHVDGVTPDDVLALTFSRKAAEQLRDRVTSRLGRTMATGLSSTFHSFAYGLVRRYAPAELYVAPLRLLSAPEQDVVLQELLTDAPESVRWPDALRAAVGTRGFAREVQAVIGRARERGLDPDQLVELGRRDGVVEFEAAGLFLQQYLDVLGDQAAIDYPDLIARGVIEAERHRAELRERYRHVFVDEYQDTDPSQVALLRALAGDGGNLTVVGDPDQSIYGFRGADVRGILDFPAEFRARDGSPATVVALGTTRRFGSRLLRASRTVAASIGVSGSIPADQYAAFRNPEAAPHGLGRGSVEVLTFDTARAETEHVADLLRRAHLADGVAWSDMAVLVRSGRASIPALRRSLAASGVPVEVASDDTPLVREPAVVPLLSALSVILHARPPRSTTDDAAADDDADVDDPEDPDFVGADVVEGLLTSPLGGLDATDVRALTRALRARDEETRARDLVRAAILDPSRLEGLSGPGVRRAARLATLLQQGREALAGGATVEEVLWTVWEGSEWGPRLRQGTQSGGHAARLAHRDLDAICALFETAARAEEQRGHTSVSSFVETLRAQEIPADTLAERGVRGDAVRLLTAHRAKGLEWRLVVVAHVQEGAWPDLRRRDSLLGADRIGADRFGTGELLPPLTRRAMLAEERRLFYVAVTRARQRLVVTAVRSPDDDGEQPSRFVDELGRKPEHRIGRPPRPLSMDGLVAELRRVVADPAQSETLRRAAAVRLRRLAGTEVNGHAVAPQADPVSWWGLRAPSRSELPVRPDGEPLVLSASALEGLLTCPAQWFLQREAGGAVVSSTSQGFGKVVHAIAERIAKADLPPDADLDVLVDEVWSRMEFRTPWSGDREREAVAAVLARFVAWHGRPDARTVIAVEPKLRAEVTLPDGEVVRLHGYADRLELDESGRVVVVDLKTGKYPPTGAEVAEHAQLGLYQLAVDHGAADEAAAEHVEGPVRTGGAELVQLRHGDVLPKVQQQPAPGEGPRLAVTQLAQAVATLRAEDFVARPGKQCDRCSFQAICPDKASGTVLS
>NZ_CP040695.2|WP_148240483.1|1575708_1577217_+|potassium/proton-antiporter
MDPADLDLVVLAVAGVVLAAVVAVRVSSRLGLPSLLLYLALGLAIGEAGLGLEFEDADLTQVLGTVALAVILAEGGFTTDWRVVRPVAPLASVLATVGVATSVAVTSTIVHVVLDVDLRTAILLGAVASSTDAAAVFSVLRALPVRSRLRSTVEAESGFNDPPVIILVTVVASDAWGTASGLSILGEVVVQLVLGVVVGVVVARIGLWVLARSALPASGLYPIATLAFAFLAFAVAGVAGGSALMAIYVAGLVLGNGTLPHRTSTAGFVGGLAWLAQIGLFILLGLLASPGRLWDALPHALVVGGALTLVARPLSVALCATPFGVPWREQVFVSWAGLRGAVPVVLATIPLSAGLPAAERVFDVVLLLVVVFTLLQGPTLPWVARVTGAASAENPRDVTIESAPLDDLGATLLQLTVAPGSRLAGVEVGELRLPPRAAVSLVLRAGEVFAPSPTTGLRVGDHVLVVAPRADRAPVERRLRAVSASGRLAGWYAALPGEAVRR
>NZ_CP040695.2|WP_137295422.1|1575161_1575722_+|hypothetical-protein
MEEHPDTVLWLLLAVPVIGLLAATLLRWVPTGHLLVVTRRGVVSRVVRPGVAVRGPAGDAVLVPTEPEEVPLHVRATTRDGTAVRMLVRAEVRLVPPTPLERYTDPVRAAVPSAERVLQAAIEDDPHGDLHDLPVRLRRSWPRLTALADRETTPRGLRILSLELAELDAVLVPSLVDLPGDGVGPR
>NZ_CP040695.2|WP_137295421.1|1574029_1574971_-|sensor-histidine-kinase
MPLYWKVVLVNGAVFCAGTAALVLSPASVSQDPLVSELVVLTLGLAAMLLVNAALLRASLGPVDRVVREMRVLESPGGGRRLGDAGGAGPGAVLVRSWNGMLDRLEAERASSSQRALAAQEAERHRIAQDLHDQVGQSLTVVLLGLKQVEGLAPPGLVEELALVRDSARAGLDDVRRVARQLRPGVLDDLGLHSALAALATEFSAAGRHVRRSVAPGLPDLTPEIELVLYRVAQEALTNVARHAGASQVEVSLGRVGDAVVLEVADDGVGTRDSPPGTGLAGMRERALLVGGRLSVEGREGRGTTVRLAVPLP
>NZ_CP040695.2|WP_138875516.1|1573364_1574033_-|response-regulator
MTGATRTGPTRILLADDHALVRRGVRLILEREPDLTVVAEAGDGAEAVALLRGTEVDLVVLDIAMPRMTGLQAAREIARRRDPPRVLMLSMHDNEQYFFEALRVGASGYVLKSVADEDLVEACRAAVRGETFVYPGAMSALVVDYLGRLRRGETVPSTVLTEREDEVLKLIAEGASSKEIAATLTISVKTVERHRANILARLGMRDRTQLTRYAIRAGLIEP
>NZ_CP040695.2|WP_138875515.1|1570013_1573310_+|peptidase-M14
MLSPTTGVPLKRTLATLSCSALLASALALPATDAGAAVPFAGRTATAAAPDPDSAGRGAATATRVAPLEKAEVARRAAAAPVSGDPLEMPTSYPYQPELRLYRDNPDDAAHTAELLGHPDLAPQLLDWMAESDRISTQVVGQSTAGRDLYLVTVTAPERAEDTAQQTAWKEELKDDPEAASDNAELLAQYKTPVWVSANIHGNEWEGTDGVMQYIDWLVHAPTSEVGSILRNNRLYFSLSLNPDGRTLATRATALGLDPNRDMITNTTPETRSFVRTAQAIQPLYSADLHGYTNVLQVEPCGPPHGSNYEYDLYMPHNYAIALDVEADVVAANIPGNTYYNIATGQTSPTNTGPETAHIKIPYRDTASGWDDFPPIFTAQYAAFYGAATATVELPLTRGASGGRQTPARAVVNTAVAVQTVKSMVEYMNVPTNAREMLLNQAEVFRRGASGEAKVSMSTENIADVPGPTQWKPLWDVADDQEPVSLPRAYVIPVGDDQRSASDASSLVEKLLFHDIEVGTLDAAATVGGTTYPAGSYVVDMHQPLRGLANSLLDLGDDISDKVPSMYDISAWSYSYLWGATVDKVGATTDAALGAVTPVTAPTSVASMPADGYLTFEAAGLADMQAVNALLDEDVAVSMLADGSVVVAPGDRDAVAEVADGFDIAVEKATPADVAALDDESTKALSDLTIAYAGTQDDRLSLGELGFDELVSVTAAGINTAATSGTATGLEDADVLWIGSTFNLTAGSPGRLAVQAFVDGGGSVLGRGSAAFNAAAAYGLVTGTAVTGNSGGNGIVAVDTPADSLLAPYAQDTSFIYPATWFTGLGAGTEVEQTYGADPLLAGHWRASGAGVNGPDNAANQPSVVSGEVASGARSVVFGTSVLFRTHPKGGLSQAARALLWAGPEGLGVPGPEATTISLEATTPVVYPAKVAFDVEAATASGPAAGSVAILDAAGRTVGSADLAAGSATVSAAVLPGTTSYTAVLTPASAAVEPATSSPVTVTVAKASSTTSLKARKVGPRKVRLTVGLVVRGLRPVGPVTITDGGRKIKVVSFGGSATTRTFVVRLPRGRHSLRAVFAGTAVAAASKSAPVVVRITR
>NZ_CP040695.2|WP_137295428.1|1588084_1588354_-|mycoredoxin
MPDNADQASTNFTMYSTPWCGYCHRLRSQLDREGITYDVVDIEQHPEAAKIVETANNGNQTVPTLVYSDGTAQTNPSLAQVKAKVASLA
>NZ_CP040695.2|WP_138875522.1|1588434_1590489_+|AAA-family-ATPase
MPPSSDDLLSALDPEQREVAETLRGPVRVLAGAGTGKTRAITHRIAHGVASGVYVPTEVLAVTFTTRAAGEMRARLRRLGAPTVQARTFHSAALRQLRYFWPHVHGTELPTLVESKIPIVVGAARQLRMRTDQAMLRDLASEIEWAKVSNVRPDDYVEVAAARGRSVAQLEADQVARVIGAYEDVKREQGRMDMEDVLLLTAGVLAEDERVAAQVRRQYKWFVVDEFQDVSPLQSALLDLWLGGRDELCVVGDPAQTIYSFAGANADYLRDFPRKHAGTTSIELVRNYRSTPQVVGAANTLLAGTGSTSVQLRAQRPAGAAVTYTGHPDEVAEATDVAGRVAALRSAGRPLSEIAVLFRINAQSEAYEEALTEAKIPYVIRGAARFFDRPEVREAVTRLRGAARSGAQAADGDTWVDLVRDTLAGMGWTTEAPTARGQTRDRWESWQALVSQAEAFAGEAASGGDGGLNAFVDDLDRRAAEQHAPVAEGVTLATFHAAKGLEWDSVFLVGLQDGTLPITYAQTPAAIEEERRLLYVGMTRARVDLAVSWAAARNPGQAARRKPSRFLDPLLPDSARPVARGKARAKGARTCVECGKPLSTAERTRSRCSDCPVPYDEALFERLREWRKQRAAEEEIAAFMVFSNATLEAVAERRPTTPKALLAISGVGPEKLEKYGQELLELVS
>NZ_CP040695.2|WP_138875523.1|1590626_1590875_+|hypothetical-protein
MENIMTMTTSTTSNPCQTSDFGMPTRGRRANIAGEQRFPTTGLSITGPIARDLRDRKDLAAKGHVALVAYVPGIHAWSPPLC
>NZ_CP040695.2|WP_137295431.1|1591079_1591415_+|WhiB-family-transcriptional-regulator
MTTSVLTRSDGKLLEFQSTSGLGDLHDEAGKVDEALLPCRANNPELWFAELPADVEFAKALCQTCPVQQICLGGALDRSEPWGVWGGELFLQGTVIPRKRPRGRPRKDAVA
>NZ_CP040695.2|WP_138875524.1|1591411_1591639_+|hypothetical-protein
MTSATRSIQHTQTTDPNGSTTMNTMQEDLARAHMSMRLGEAQSMRAGHQLARARRLSRKAERAAQQARLALARAL
>NZ_CP040695.2|WP_138875525.1|1591949_1592711_-|hypothetical-protein
MPAPPRLRPGVHVVVRDADHVQLGLDPPARVIVARRPEVARVLERLTAGLPPAPTTPEGAAVVRDLAAAGLLVVPETAPTGSVRLVSRGLDLAPLGVLLEDAGLTVTRSDPLPDLYVVATPGPLPRAVVDGWVGEGAPHLVVAGTSRPGGLRVGPLVEPGTTACLRCVDAHEATHDPRRPLLVEQLAALPAAPVDRRVVALATAWAARDAVDFLAGRRPVTWSGTVDLDGPSPVVRTWDRHPHCGCGWDDVPY
>NZ_CP040695.2|WP_138875526.1|1593156_1593951_+|enoyl-CoA-hydratase/isomerase-family-protein
MPELAHLRLLRPSDGVVLLVLDNPDQRNAMSPEMTSSWVAAIDQVAADRSVRAVVVTGEGTAFCSGGDTAWLAGEPNATVDHLRDRMLPFYRAWLSIRRLEVPTIAAINGPAIGAGLCLALACDLRHAAAGAKMGVPFVKLGLHPGMAGTALLPDVVGAAAARDLFLTGRIVDADEALGLGLVSRVVDPETFLDTVLETAAQVAATAPIASRLTKLALAGGGHADVETGLQWEALAQPVTLATDDLQEGLRAARERRAPVFRGR
>NZ_CP040695.2|WP_138875527.1|1594286_1595363_+|PHP-domain-containing-protein
MNASDEPYEAGPVAALRRIAFLLERAREDTYKVKAFRGAAATILPLPAEDVARAVEAGTLTDLPGIGASSGKVIAAAVRGQVPERLARLEAEHAGPLTDGGAALRAALRGDCHSHSDWSDGGSPIEEMAMTAIELGHEYLVLTDHSPRLKVARGLSAERLQRQLGVVDAVNEHLGGGADGGGAGGEPGFTLLKGIEVDILDDGSLDQSEEMLDRLDLRVASVHSKLAMDAGAMTRRMIGAVRQRHTNVLGHCTGRLVTGGRGTRQQSSFDARAVFEACAENDVAVEINSRPERRDPPFALLALARDAGCVFSIDSDAHAPGQLDFLQLGCERAEDAGIDADRIVNTWPRQRLLEWARK
>NZ_CP040695.2|WP_137295436.1|1595373_1595907_+|M48-family-metallopeptidase
MGAGEVEVRRSPRRLRTVSAYREDDRIVVLIPASFSAADEAEWVETMVARILRSEQRVPLSDDELRVRALRLSDRHLGGLAVPESVRWVSNQHTRWGSCSLGERAIRLSERLQAMPSWVLDYVIVHELAHLIEPGHDERFWAWVDRYPRAEKAKGYLLGWSEAAKVSLPSEFDSHVD
>NZ_CP040695.2|WP_148240485.1|1595837_1596437_-|NUDIX-domain-containing-protein
MSSLHADALGVLRAWVPPEAEGQAALRERYVAYLESHPDAMTRASRPDHLTASTLVLDVGRTHALLTLHAKAGRWFQLGGHAEPGDATLADAALREAVEESGLAPSDLELDPRPAWLDAHAVPFCGSGEGVTHLDVMYVAVARPGAVHAVSEESLDVRWWPLEELPNEELLPRVRRLQSTWLSNSEGSETFAASDQPSR

Crispr_ID: NZ_CP040695_10

• CRISPR_ID: NZ_CP040695_10
• CRISPR_location: 1814034-1814122
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_10

Consensus_repeat	Method
GCTCGCTTGCTCAACCTCCGGTGGTGGTCGGC	CRISPRCasFinder

spacers of NZ_CP040695_10

>10.1|1814066|25|NZ_CP040695|CRISPRCasFinder
TCCGGTTTCGTCGGCGCTCGCTGGG

CRISPR arrays and Neighbor proteins around NZ_CP040695_10

CRISPR arrays

The CRISPR arrays of NZ_CP040695_10

>merge|NZ_CP040695|10|1814034-1814122|CRISPRCasFinder
GCTCGCTTGCTCAACCTCCGGTGGTGGTCGGCTCCGGTTTCGTCGGCGCTCGCTGGGGCTCGCTTGCTCAACCTCCGGTGGTGGTTCGG

>NZ_CP040695|10|10|1814034-1814122|CRISPRCasFinder
GCTCGCTTGCTCAACCTCCGGTGGTGGTCGGC	TCCGGTTTCGTCGGCGCTCGCTGGG
GCTCGCTTGCTCAACCTCCGGTGGTGGTTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138875638.1|1818320_1819364_-|glycosyltransferase	unknown	unknown	gnl|CDD|133030
NZ_CP040695.2|WP_138875632.1|1805444_1806662_+|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
NZ_CP040695.2|WP_137292150.1|1822679_1823642_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187540
NZ_CP040695.2|WP_137292159.1|1812692_1813637_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|181818
NZ_CP040695.2|WP_138875633.1|1806676_1808839_+|transglutaminase-domain-containing-protein	unknown	unknown	gnl|CDD|376628
NZ_CP040695.2|WP_137292149.1|1823716_1824301_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NZ_CP040695.2|WP_138875634.1|1809827_1810724_+|phosphotransferase	unknown	unknown	gnl|CDD|270703
NZ_CP040695.2|WP_148240512.1|1801469_1802627_-|glycosyltransferase	unknown	unknown	gnl|CDD|340831
NZ_CP040695.2|WP_137292166.1|1803513_1804455_+|DUF3068-domain-containing-protein	unknown	unknown	gnl|CDD|371444
NZ_CP040695.2|WP_137292165.1|1804486_1805452_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|285027
NZ_CP040695.2|WP_138875640.1|1821835_1822534_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379115
NZ_CP040695.2|WP_148240514.1|1820618_1821656_-|GNAT-family-N-acetyltransferase	unknown	unknown	unknown
NZ_CP040695.2|WP_148240513.1|1819354_1820611_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137292156.1|1816402_1817062_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137292148.1|1824300_1825242_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP040695.2|WP_137292265.1|1802674_1803424_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP040695.2|WP_137292160.1|1810837_1812307_+|30S-ribosomal-protein-S1	unknown	unknown	gnl|CDD|236126
NZ_CP040695.2|WP_138875637.1|1817058_1818324_-|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|235010
NZ_CP040695.2|WP_137292162.1|1808906_1809767_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_CP040695.2|WP_138875636.1|1815392_1816406_-|GNAT-family-N-acetyltransferase	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138875638.1|1818320_1819364_-|glycosyltransferase	gnl|CDD|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.07846e-48
NZ_CP040695.2|WP_138875632.1|1805444_1806662_+|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	2.34596e-24
NZ_CP040695.2|WP_137292150.1|1822679_1823642_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187540	cd05229, SDR_a3, atypical (a) SDRs, subgroup 3. These atypical SDR family members of unknown function have a glycine-rich NAD(P)-binding motif consensus that is very similar to the extended SDRs, GXXGXXG. Generally, this group has poor conservation of the active site tetrad, However, individual sequences do contain matches to the YXXXK active site motif, and generally Tyr or Asn in place of the upstream Ser found in most SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	9.49334e-70
NZ_CP040695.2|WP_137292159.1|1812692_1813637_+|helix-turn-helix-domain-containing-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.75346e-109
NZ_CP040695.2|WP_138875633.1|1806676_1808839_+|transglutaminase-domain-containing-protein	gnl|CDD|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.91792e-07
NZ_CP040695.2|WP_137292149.1|1823716_1824301_+|RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	3.29838e-32
NZ_CP040695.2|WP_138875634.1|1809827_1810724_+|phosphotransferase	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	2.83941e-14
NZ_CP040695.2|WP_148240512.1|1801469_1802627_-|glycosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	6.16048e-50
NZ_CP040695.2|WP_137292166.1|1803513_1804455_+|DUF3068-domain-containing-protein	gnl|CDD|371444	pfam11271, DUF3068, Protein of unknown function (DUF3068). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	2.20306e-59
NZ_CP040695.2|WP_137292165.1|1804486_1805452_+|AAA-family-ATPase	gnl|CDD|285027	pfam07726, AAA_3, ATPase family associated with various cellular activities (AAA). This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.	3.85332e-86
NZ_CP040695.2|WP_138875640.1|1821835_1822534_-|TetR-family-transcriptional-regulator	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.09638e-09
NZ_CP040695.2|WP_137292148.1|1824300_1825242_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000118066
NZ_CP040695.2|WP_137292265.1|1802674_1803424_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.47595e-19
NZ_CP040695.2|WP_137292160.1|1810837_1812307_+|30S-ribosomal-protein-S1	gnl|CDD|236126	PRK07899, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP040695.2|WP_137292162.1|1808906_1809767_-|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	9.99876e-23
NZ_CP040695.2|WP_138875637.1|1817058_1818324_-|ATP-grasp-domain-containing-protein	gnl|CDD|235010	PRK02186, PRK02186, argininosuccinate lyase; Provisional.	2.44874e-24

Protein sequences

>NZ_CP040695.2|WP_137292159.1|1812692_1813637_+|helix-turn-helix-domain-containing-protein
MQKVAVIVQDGAEPFGLGSLVEVWGEPYHADDDNPVFDFQVCTPRPGRVTGRAGYDLLVDVGLEAAADADLVCLSPKYDFLDHDPAVLEVARAAHDRGAIVYAHCSGVFELAAAGLLEGRECTTHWRYTDRLARMYPDAIVRPDVLYVQSGNVLTGAGSAAGIDASLHLLRQTFGARVAATTARRIVVPPHRDGGQAQFISRQVVDCQAETLGAVLTWALENLAEPLDVDTLARKAHMSPRTFARRFRDETGTTPHAWVTAQRLQLAEEMLERTDNSVDHIAAEVGFGNAATLRHHFTRVRGVSPQVYRRQFAC
>NZ_CP040695.2|WP_137292160.1|1810837_1812307_+|30S-ribosomal-protein-S1
MTIAFLPDYDAPQVAINDIGSEEDFLAAIDLTIKYFNDGDIVEGTIVKVDRDEVLLDIGYKTEGVIPSRELSIKHDVDPSEVVSVGDKVEALVLQKEDKEGRLILSKKRAQYERAWGTIEQVKEEDGVVEGTVIEVVKGGLILDIGLRGFLPASLVEMRRVRDLQPYVGQVLEAKIIELDKNRNNVVLSRRAWLEQTQSEVRHGFLTQLQKGQIRKGVVSSIVNFGAFVDLGGVDGLVHVSELSWKHIDHPSEVVTVGDEVTVEVLDVDMDRERVSLSLKATQEDPWQHFARTHQIGQIVPGKVTKLVPFGSFVRVEEGIEGLVHISELAERHVEIPEQVVQVNDDVMVKIIDIDLERRRISLSLKQANETATATDVDEFDPTLYGMAATYDEQGNYVYPEGFDSETGEWLEGFDDQRAVWEEQYAKAHARWEAHVKQQADAKTADAEAGEATSYSSGGDDVDTEGDGGSLASDEALQALREKLTGGQA
>NZ_CP040695.2|WP_138875634.1|1809827_1810724_+|phosphotransferase
MLDDDFASLRPLEGDRSGETFVAEVGGERQVVRVYARDPARAEVDAALLRLVRGLVPVPDVLEVRPPRGDLPALLVTSFVPGVRGDLHLASLPDDLSGGFAWALAEVAATLAGMPTLTRGALTGAGLRIEPLDGGADGLPAHVEARRPDLAHWSSEELAGLDEVAGTAQALLDTVDRSCLVHGGLEPRNVVVDPVTRWITAVVGWEHAHAGHPFADLGSVLRLDRGPAYVEVALSAFEDRHGVPPDEALALARAADLWALTDLAGRRRQDPAAQRAHDLLRGIAASRDLGWTLPEAPA
>NZ_CP040695.2|WP_137292162.1|1808906_1809767_-|methyltransferase-domain-containing-protein
MPGADPHAPDSRHHPDLPDSVRSVRRPVTEEQSRRANGPDWDRYADEYQATHGAFLGDVGFVWGPEGLTEAEAGVLGDPAGLAGRDVLEVGSGAGQCSRWVRARGGRAVGLDLSHRQLQHSRRIDDETGVRVPSVLGTATHLPFADASFDVVFSSFGALQFVREIDAAVAETARVLRPGGRFAFSITHPTRWMFPDDPSAAGLTASQSYWDRTPYVEVDDATGEVTYVEHHRTLGDWVSLLAGAGFVLTTLLEPEWPAGHDRVWGGWSGVRGAITPGTAILGADLR
>NZ_CP040695.2|WP_138875633.1|1806676_1808839_+|transglutaminase-domain-containing-protein
MSGARPASTPTRTDGVLADAVLALLASGVVLLAWQPTYAGSGWWIAGLSASFLAVMVAVAVRDAGGGGEVVTLGLFAGYLVVAGPLARGSLAVEGWDTVTDGIRGSWEVWHQLLTTHPPVTAAGPTLLPPILTGLVSGGFAATLALGSRRPAVPLVPVALALGAVLLVGQHQAASVLGVGVGAGAVAVVWLQVRAARLEAEEIGRDPARRRRTVVALVVVALCGAASLRLVGGDPVEDRYVLRDGVRPFAVSGIVTPLDSLRDLVLSDRKLLQVDGLPAGHRLRFVALDRYDGQSWTADNDTDPVRDDDRFLHVSETVENPAAGEVREVTVRATRYWDRPWVPTVGAVQSLGFQGSDADLGSDLLYNPATQSALLPGGLDADVRYAFTAIDTDRLADRRVEGSAAYDEELRDRLQVLDEVVSYWSIGAYTPMDALSKVAEGIRKVGRYSHGVEPWEQRFESGHDLRRLTDEFLLTVPTVGDEEQYAAAMALLATRMRIPARVVVGAVVPRDGAVRGSDVTAWVEIRAEDGTWRTIPAEVFMSRKPPDRLTAGGPVDRDYQPPSDVEPQLPDARPEQPADREDGPDADRDRGAAWWLLLPSVLLLLVVAVPAAKWVRRRRRLRSRRVSARYAGAWDELVDHARDLGVDVPVSAARPGQAAVLEGTLPLALEADRRIYGAGDLDPGDADAFWELVRAELREMDAAVPRWRRVLALLDPRTLR
>NZ_CP040695.2|WP_138875632.1|1805444_1806662_+|DUF58-domain-containing-protein
MREPLRLLGSLTSSVSPAGWTVGGLGVLAAVAGRVGGYVELQVLAVLCGLVLLVSLVLLVVAPGRVEAKLELRPASTVAGTPGRALLRVTNRGRWSVRHPVVTVPVRAGAVVVERGFVRLPRLRPGVQHQEEVVLPAMERGIVQVGPVGARRTDPLGLFRRDRDWTGVADLAVRPRMTPIETMAPGHVPDHDGTPSEEVSMSDLAFHALREYVPGDDLRHVHWRSSARAGVLHVRQYHDTRRSHVVIVVDRHEESYPRAQDFELALSIATSVAVRLTEEGYTLTFVCGPDVGADAIGVVLDASCRAVLGPDDLEESARTASRMAPGSSQLVVVSGVLGAPQRVQGCRAAFADDVRFLGLATGRVPGESRDDPPRDLGAGPARMLRVRRMAELPGVLAASVLGEGR
>NZ_CP040695.2|WP_137292165.1|1804486_1805452_+|AAA-family-ATPase
MTLSPDQASRFQRVFTDVVDNMGLALLGKDRVVRLAVTCLLAEGHLLLEDLPGTGKTMLARALANSVEGSHARIQFTPDLLPTDVTGVTVYDQHKGTFSFHEGPIFHDIVLADEINRASPKTQSALLEVMEEGHVTVDGTTHDVPRPFMVIATQNPIEQAGTYQLPEAQLDRFLMKTSVGHPGAEATEQLLMDAGVRDRASLVKPVLSRADVADLAAAAAEVHVDRSLIRYVRELAEASREADQVKLGLSARGCLALIRVTKVWAAAAGRTAVVPQDIHDLAHPVLCHRVLLDAHAQYGGVHVDAVIDRLLRDVPPPRDRA
>NZ_CP040695.2|WP_137292166.1|1803513_1804455_+|DUF3068-domain-containing-protein
MRTILGRVLIALGGFLLVAGLVALVWAPGVVKKTPVDVDSVTHLSGEGGRVDTATGQITVGPVVASSITKVDTDASDDDVAVFVSTSCLMKDEGDVPDCLDGDDDRLLSASTSLFATDRDTALSVDNGSYLPEGSPQPRGLQNKWPFDAEKKDYEYWDGTAGVSVTAAYDREQDILGLKTYVYRVVVEDAPIEVAEGVEGTYSSTKEIYVDPVTGAIIHQTDDQERYIGSGAEATQALELQLAFTEDQQQTNVDDAESNATSLALVTKWIPIIGLVGGLLALVAGILLVLREGRRTDHAVADDVYADKTTTDA
>NZ_CP040695.2|WP_137292265.1|1802674_1803424_+|class-I-SAM-dependent-methyltransferase
MPGRATSPTRRRSTLRRSVALLRAFRHEQPDPPRFYTALARDSVEQLSGYADLDGALLLDVGGGPGYFRDAFTAAGARYVALDADVGELSGLGEMPPGTVLGSGMALPFRDASLDVCYSSNVLEHVSDPWLMAEEMLRVTRPGGTVFLSYTVWFGPWGGHETAPWHYLGGRRARARYRRKHGREPKNRYGESLFKVTVAEALEWSRRQDLADVVEVLPRYNPAWSWWLLRVPVVRELATWNLALVLRRR
>NZ_CP040695.2|WP_148240512.1|1801469_1802627_-|glycosyltransferase
MHPLDDLAGKHVVFLSWRDTRNPEGGGAERYLEKVAGGLAALGCRVTILCAAHAAAPPDETVDGVHYVRRGSKITVYLRGMLALATRRLGRVDLVVDVQNGLPFFSRLVTRAPVVVLVHHVHREQWGVLFGPLMARVGWWIERRFAPWLYRRCQYVAVSRATRAELAELGVDPRRVAVVHNGTDRVVRVDETKAPEPTIAVVGRLVPHKQVEHAVDAVVALRAEHPGIHLEVVGNGWLGGEPPRVRRRARRDLVTFHGHVEEHTKHEVYARSWLLALPSIKEGWGLVIGEAAMHATPTVAYSSAGGTRESVRADVTGLLVDDQDGLTAAIDRLVRDHDLRARLGTAALAMSHSYTWEHAQESFGVVVLAALEGRVIDAQDPDEGA
>NZ_CP040695.2|WP_138875636.1|1815392_1816406_-|GNAT-family-N-acetyltransferase
MSDSDAGPDDVPYDVRVVDLAGLRGDAVLAAHLATSRGPLWRVEALSAMEEETRNRVWLAVATRSGPAGDALVAGILLERVLLAGGIGHVHHPHSGSEPSYWSEPGHRGALPLLVGALRRRLGPRMPALLWRQVGDDDVASGLPGRRLVQQTTLPLGVVDLDRADAEAWLQSLGRSRRQDLRRLRRRLAEDVDLDVTQGPLAEVAKGEEVAPLLDANFSKHNPRRHPLMNRPAPAAWLDVAMADHDLQAVAYRDRGVLSAVGLMSTHRGVSRWLSWGADYEGAADRRGLYYDCTRRIVELSYAAASTTLVLGKGKGELKSSFGARLEGQRAVVRTPI
>NZ_CP040695.2|WP_137292156.1|1816402_1817062_-|hypothetical-protein
MKQGIATLGFGAAAAVTAWAVHHWVANDVETLVSLLFALVPFVLATEAVARVPRAWAGARWMAPLMVSAVFLAVMGGFAPLMFGAFVDEDFDRFYSIMRMLVPFVILGLVFALRLGGATGATVRRASYAALLVMLSGIEDLMFQVWRGNDIPDRWEWAEHITVRLGGHVASQNEAFAFIAAHFVLAAVVIFAPIPGRRSRPGAGTDDAADDRAPTAVPS
>NZ_CP040695.2|WP_138875637.1|1817058_1818324_-|ATP-grasp-domain-containing-protein
MKRRRSRGSVVVLGAAIGVFETYRAAQRMGLRTIAVDVRPDAPALGLADERLIISTRDVDAVHEALLGRDDLRGVVAPASDVALDAQRRLSRRLGLPCGLSAATVRASHDKTYLRQVCDDLGLPTCRWATGVPGPPLLRETERLGLPVVVKPADAQSSRGVSRCREGDDLTAAIAEAAAFSYSGRVIVEEEMLGQHLSAECIVEDSRAAFLGLSARTITRAPRAITTEHAMSGELPGHVVDQVHDLVDALCRALDYRRGPMMLDLVLGADDTVRIVEIGARVGGDPLGELVRLTHGVHTVENAVRAAVGLPFDLGRRRRPSAAVGRIILPDAVGTVAGVRGAGPAAMLPGVERVRIGAQQGDRVEGGACLADQLGYVLTTAPTVCEARQRALDAVGGLTFDITTDAGDGAGEDMTKELMAG
>NZ_CP040695.2|WP_138875638.1|1818320_1819364_-|glycosyltransferase
MDMREDDPCATGLSVVMPCYNEAGGLDDVLDELLDELDREPRLDVEVVCVDDGSRDGTLDVLRRRAAADPRVQYLSFTRNFGVEAAFSAGYLYASKPWLVHVDADGQFPPSEIRRLIEASDGMDAVFGVRVQRHDPLVRRIGSTVNQLVARGVLGIELPRHATCFRLVRTELARAVVDLRLGSPYFLATLPKLTDRHTTVPIAHRARTDGPARVRFLHLAGHALDLWFAFSRRPAQFAILTAIWAAVVSVALGVLHMTRALPAPVMEGGIVVLVGIALFVIAVEVRCLGVLAAGQPRPRMFYVREASVPVLPADTFGSVATGRPVGPLGAVGAVGPVGPVAPVEVAS
>NZ_CP040695.2|WP_148240513.1|1819354_1820611_-|hypothetical-protein
MSIAAAPTTSVPYAPSWVSTGVVLAGRAGFRALWMVAPLLLATTWTADELGRTVAVIGGFGWLAILFATAEKTLLKQVPRLPRLAGQVSRRTVATVLVPLGCALGAATLSTLTGAGPTLLLWGLCWGLTGAAYQVVAALHRLAHRPGADALLFASGALALLTATGVTVALDLRPVAWVVTCLVLLLAVAAAGLAAVPRETFRGVGRRAAVGPLRRSLLLLGLPEVLSIVSVSAGFWAVAALAPEQEAVRYYVAVTVASVFGATTTVVVRLHQPDVSLRLRGSGAAAGEDAARRILARATTAGAGTAALAVGAHLLGAPWWATLALLTLGEVVVFTQRTVAANLVENSRSRWLPGNVGASACGLLAASVVLLACTARGGALAAMGALVAAQLCNATALRLLLRRASGRRVPQPISGRWT
>NZ_CP040695.2|WP_148240514.1|1820618_1821656_-|GNAT-family-N-acetyltransferase
MPGSTHALTTRVTLAGSGEDQPGWAELVRDEGLVALWDHDLLQLSALSPTPWCPTFTAAVRHGDTIVGAFVGSYRGVRPHAAPSRLEPVLVDMRMPGQGHEASWAFRSGLTRPQRADVVRAFERGVVRALGRTRLAGIAYRNVTDDDLPDLRRRGAVVSQAQGQGTVMPLPATFEEWFAGLSKKRRKSLRRLGPMIESQVRVEFGNARTDVDPQAVADLLVAMIERNAPLRVDPRPHMPAAYFAALMARDDVRTITYHQGERLVAVGTLLEHPRHPWGSYWAMVHPRDGGVPHLYFDHFLRYARHAIDSGAETLSSGRGFVDDKVSVGFDVTPLSFVGVPRPFLG
>NZ_CP040695.2|WP_138875640.1|1821835_1822534_-|TetR-family-transcriptional-regulator
MPAAPRTARATARAELTRAILDSAATQLADVGPAALSVRAVARDLEMASSAVYRYFPSRDALLTALIIEAYDDLGAAVESAERAVRRGDLRGRWRAVAHGVRDWAVGHPHRYALTHGSPVPGYAAPVDTVVPATRVTLALLTVLRDAQAAGRTPAAGPARVPAAEKAALGPVMAFVDPPLSPAFAVRGLTAWATLFGHVSLELFGHLHRGVLDYDTHFATVVDQLGADLGLT
>NZ_CP040695.2|WP_137292150.1|1822679_1823642_+|NAD-dependent-epimerase/dehydratase-family-protein
MGRHVVVGAGPVGLATVRELVAQGHGDVLLVSRSGRGDDVPGVRRVALDVADAEALTTLAEGAGALHNCVNPPSYDVWSTWWPPVARAFLVAAERTGAVLVTASCLYPYGPTDAPMTEGQADRAAGVKGALRATMWADARAAHEAGRLRAVEVRGSDYAGPGVTTAHLPTVAPRALAGRSVRVFGRADVAHSFTDVRDMARTLVAVAGRPDTHGRVWHAPTNPPRTQAEAVADVCRAVGREPVRVRPWPRALLGVGGLVVPLLREMRETVHQFERPYVLDSSLTQRELGLAPTPWDDVCRATAETALGGVVPGTEVSRPA
>NZ_CP040695.2|WP_137292149.1|1823716_1824301_+|RNA-polymerase-sigma-factor
MSPPEDTMTQSEAALAERLRLGDPEAVAELFDRHADRIHRHCFRLTADRADAEDATATTFLEVWRHRHRVQVHDGSLAPWLHGVATNVCRNLTRGRRRHLRAVARLTAPGDQPDHADRVGERLDTERRMRVVLDAVATLPPHERDVLALVVWSGLSYEAAAAALEVPVGTVRSRLSRARRRLTALAPTDAGGTP
>NZ_CP040695.2|WP_137292148.1|1824300_1825242_+|hypothetical-protein
MDDDLTTPPDQPLDDAARARLRGRVLAGLAEPAASGSGRRWAAPAAAAAAVVVLAGATGWATLAPGAEDVAPADRGTSSPEVLPTPTPADDVAVPDPSDGSDRPDDPTGQGGVTPHEGPAVEPTPSGAGPAGGPAVACRRDLDDVLPGAVPALTLGGTLGATSFLVGGDRFVLCDTAGGTVTLHGAQPLDGRHAPDDTTPWRVSTNAVDPQDGTGGLDLVLVAGGIVPPRAEGWGISYTFPDGHVEEATTGTDAEGRTWWRMEHVATDGVLVARGTDQTTLEPILVDVRVAGTSTEHELRWGEDTCAQVNHGC

Crispr_ID: NZ_CP040695_11

• CRISPR_ID: NZ_CP040695_11
• CRISPR_location: 2059212-2059301
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_11

Consensus_repeat	Method
GAGTTTCACCGCTTGAGCGGTGAAACTC	CRISPRCasFinder

spacers of NZ_CP040695_11

>11.1|2059240|34|NZ_CP040695|CRISPRCasFinder
ACGCTCCTGTCGTGAAGTTTCAGCCGGCAAGCGC

CRISPR arrays and Neighbor proteins around NZ_CP040695_11

CRISPR arrays

The CRISPR arrays of NZ_CP040695_11

>merge|NZ_CP040695|11|2059212-2059301|CRISPRCasFinder
GAGTTTCACCGCTTGAGCGGTGAAACTCACGCTCCTGTCGTGAAGTTTCAGCCGGCAAGCGCGAGTTTCACCGCTTCAGCGGTGAAACTC

>NZ_CP040695|11|11|2059212-2059301|CRISPRCasFinder
GAGTTTCACCGCTTGAGCGGTGAAACTC	ACGCTCCTGTCGTGAAGTTTCAGCCGGCAAGCGC
GAGTTTCACCGCTTCAGCGGTGAAACTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_137291938.1|2057601_2059200_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NZ_CP040695.2|WP_148240980.1|2062030_2063947_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP040695.2|WP_138875755.1|2061165_2061984_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|119339
NZ_CP040695.2|WP_138875749.1|2051987_2052446_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl|CDD|273918
NZ_CP040695.2|WP_137291930.1|2068296_2068623_-|DUF3099-domain-containing-protein	unknown	unknown	gnl|CDD|378630
NZ_CP040695.2|WP_137291943.1|2052438_2052825_+|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl|CDD|225062
NZ_CP040695.2|WP_148240545.1|2065453_2066212_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187602
NZ_CP040695.2|WP_148240542.1|2050718_2051984_+|SufS-family-cysteine-desulfurase	unknown	unknown	gnl|CDD|131034
NZ_CP040695.2|WP_148240979.1|2059309_2060362_-|S-adenosylmethionine:tRNA-ribosyltransferase-isomerase	unknown	unknown	gnl|CDD|223879
NZ_CP040695.2|WP_148240543.1|2052843_2053938_-|hypothetical-protein	unknown	unknown	gnl|CDD|237940
NZ_CP040695.2|WP_137291935.1|2063939_2065436_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP040695.2|WP_137291933.1|2066097_2067024_-|SURF1-family-protein	unknown	unknown	gnl|CDD|119401
NZ_CP040695.2|WP_138875757.1|2067060_2068077_+|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|234672
NZ_CP040695.2|WP_138875753.1|2056587_2057517_-|peptidase	unknown	unknown	gnl|CDD|225203
NZ_CP040695.2|WP_138877119.1|2054522_2055614_+|YfcE-family-phosphodiesterase	unknown	unknown	gnl|CDD|223695
NZ_CP040695.2|WP_138875754.1|2060364_2061048_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP040695.2|WP_137291946.1|2049918_2050677_+|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl|CDD|223473
NZ_CP040695.2|WP_148240544.1|2055624_2056542_+|phosphotransferase	unknown	unknown	unknown
NZ_CP040695.2|WP_138875751.1|2053934_2054438_-|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_CP040695.2|WP_138875758.1|2068059_2068296_-|acetone-carboxylase	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_137291938.1|2057601_2059200_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	7.12169e-175
NZ_CP040695.2|WP_148240980.1|2062030_2063947_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.78208e-167
NZ_CP040695.2|WP_138875755.1|2061165_2061984_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	2.49995e-51
NZ_CP040695.2|WP_138875749.1|2051987_2052446_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl|CDD|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	5.73852e-55
NZ_CP040695.2|WP_137291930.1|2068296_2068623_-|DUF3099-domain-containing-protein	gnl|CDD|378630	pfam11298, DUF3099, Protein of unknown function (DUF3099). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	7.55461e-21
NZ_CP040695.2|WP_137291943.1|2052438_2052825_+|metal-sulfur-cluster-assembly-factor	gnl|CDD|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	2.38264e-33
NZ_CP040695.2|WP_148240542.1|2050718_2051984_+|SufS-family-cysteine-desulfurase	gnl|CDD|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP040695.2|WP_148240979.1|2059309_2060362_-|S-adenosylmethionine:tRNA-ribosyltransferase-isomerase	gnl|CDD|223879	COG0809, QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis].	4.32774e-70
NZ_CP040695.2|WP_148240543.1|2052843_2053938_-|hypothetical-protein	gnl|CDD|237940	PRK15313, PRK15313, intestinal colonization autotransporter adhesin MisL.	5.46004e-05
NZ_CP040695.2|WP_137291935.1|2063939_2065436_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.28935e-68
NZ_CP040695.2|WP_137291933.1|2066097_2067024_-|SURF1-family-protein	gnl|CDD|119401	cd06662, SURF1, SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring complex of the respiratory chain, is an assemblage of nuclear and mitochondrially-encoded subunits. Its assembly is mediated by nuclear encoded assembly factors, one of which is Surf1/Shy1. Mutations in human Surf1 are a major cause of Leigh syndrome, a severe neurodegenerative disorder.	6.53136e-44
NZ_CP040695.2|WP_138875757.1|2067060_2068077_+|GTP-3',8-cyclase-MoaA	gnl|CDD|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	7.47825e-176
NZ_CP040695.2|WP_138875753.1|2056587_2057517_-|peptidase	gnl|CDD|225203	COG2321, COG2321, Predicted metalloprotease [General function prediction only].	1.01283e-74
NZ_CP040695.2|WP_138877119.1|2054522_2055614_+|YfcE-family-phosphodiesterase	gnl|CDD|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	1.56093e-39
NZ_CP040695.2|WP_138875754.1|2060364_2061048_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.78041e-39
NZ_CP040695.2|WP_137291946.1|2049918_2050677_+|Fe-S-cluster-assembly-ATPase-SufC	gnl|CDD|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.60469e-141
NZ_CP040695.2|WP_148240545.1|2065453_2066212_+|SDR-family-oxidoreductase	gnl|CDD|187602	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR. This subgroup resembles the SDR family, but does not have a perfect match to the NAD-binding motif or the catalytic tetrad characteristic of the SDRs. It includes the SDRs, Q9HYA2 from Pseudomonas aeruginosa PAO1 and APE0912 from Aeropyrum pernix K1. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.3187e-68
NZ_CP040695.2|WP_138875751.1|2053934_2054438_-|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.23963e-25

Protein sequences

>NZ_CP040695.2|WP_137291938.1|2057601_2059200_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MITAHQLEVRAGARLLMEDVSFRVAAGDKVGLVGRNGAGKTTLTKILAGESLPAAGNVTRTGEVGYLPQDPRTGDPEVLARDRILSARGLDAVVRKMRAAEEQMASDDPNVREKAMRRYTRADDEMHAGGGYAAESEAATIAASLGIEDRILNQPLKTLSGGQRRRVELARILFSDAEVLILDEPTNHLDADSIVWLRDFLKSHKGGFIVISHDNALLEETVNKVLHLDANRCVMDVYNMGWRHYQTQRETDEKRRKRERANAESKAKTLTDQANKMRAKASKAVAAQSMLKRAEKMMAGLEGERQADKVARIKFPSPAPCGKTPLTGAELSKSYGSLEVFTDVDLAIDKGSRVVILGLNGAGKTTMLRILAGVDRPDTGVVTPGHGLKLGYYAQEHETLDTSRTVLENMQSAAPQLTDTEARSVLGSFLFSGDDANKPAAVLSGGEKTRLALASLVVSSANVLLLDEPTNNLDPASREEVLAAIRTYEGAIILVTHDEGAVRALEPDRVLLLPDGDEDLWNDGYADLVSLA
>NZ_CP040695.2|WP_138875753.1|2056587_2057517_-|peptidase
MRFNPKARLDTGRVSDAGRGGGGGGGGGGSRLPIPGGMAGGGGVIGVIAIVVFVAVQLLGGGGGGGGVSGGGLSAAKFTDTGRYADCKTGEDANNSADCARVAVENSLTDFWGDTLGSDFRAEDRIVTFEGSINTGCGGATSSVGPFYCPGDETIYLDDAFFDDVLVGQLKGPEGAFVEPYVLAHEYGHHVSNLIGTLGKVTGETGPQSTGVRLELQADCFAGMWAKHATETEDSTGNVLLLDLTQDDITTALDAAKTVGDDYIQKRSGGSVDEEVWTHGSSAQRQKWFQVGYTEGTMQACDTFGASRV
>NZ_CP040695.2|WP_148240544.1|2055624_2056542_+|phosphotransferase
MWEPEPGWHALPGGTGVSTVGVWRAALGDHPVVIKRLAAPQHGDAAELSDPTHPAYWRREADVLATGLVAATRGLRAVPASVEEDAEGLTITRPWVEDAAASGLFVAVALGRFAGVALPRPRFLARDLLRQRLARTERRAGGWPTLARTTAADVADHLWSRRGSFLDLLDALPAVAQHGDPSHVNVPGRDGDDAVAIDWATLGLGPVGCDLGYFSLTAREEFEPLLDAYLVGLAGGPMGHVDRDDVVLGARVSAVYTAFTRAEWALARVAGGEGALAGKFRHPAVAPYLRALQRQATAVEALLGW
>NZ_CP040695.2|WP_138877119.1|2054522_2055614_+|YfcE-family-phosphodiesterase
MGPVARQLRAQPRTDRPRGRGRRPDRHRGGRVALRGAAALRPRARRRARRRPGSPGRPGRRPRRLGGAPGPQGWLRDGAAARHHAGGVQDRPAPRPGPHQGRRAVAAALRPTSRQPGPAGLRGGGRPRRADPRRAARPPGHRRGPRRRRRGPGRPAAARRRRGRAVAGGPGPTALGAGAGRRRRHRAPGGGRQRVTHVLLLADTHLPRRARDLPAEVWEQVAAADVVVHAGDWVDLATLDRLEERARRVVGVYGNNDGPELRARLPEVATARIGGVRFAVVHETGAKQGREQRCEAAHPDADVLVFGHSHIPWDTTTPRGLRLLNPGSPTDRRRQPHCTYLTLTAHDGALTDVRLHRLPPRVQ
>NZ_CP040695.2|WP_138875751.1|2053934_2054438_-|SigE-family-RNA-polymerase-sigma-factor
MGVEREDEHQVEEVYARAAGPLIGLLTVLGGSRADAEEVAQDAFVRLLEHWTRVRGYDDVDAWLRTVAVRLLVSRQRRRKVAALGLGRLRARAAGSVEGPDGVRLDVGAAVAALPLDHRAILLLHHVHDLPVEEVAALLRVPVGTVKSRLSRARAALAPRLTEGSTP
>NZ_CP040695.2|WP_148240543.1|2052843_2053938_-|hypothetical-protein
MTEPLDRLVQDATPAHPPPFADVVRRRRARRLRRRAAAGVGVAAVAVVALAVVDGPGDRPGPEADDPATSASDPASDPVPSDPVPSDPVPSDPVPSEPVPTTATSPLEPDDGVGDEPPRLVLDGTRGPVLALQGSYCWGSTCADRAFPAPADVPLVAPVAPLRAAFPLAGRWDADVTPGVGDPGCARYPVLVEPAADDQLLLTPSGPGGDRMGSYFVRPEAGGDTSGLWRWPVPARDGRALAWLDLRQNTPSSGGEAGVTLHVDDAAVDGDVSASVRITAADGAVGRTVALPRTDQHCDGDGFVELGTPWGVRQQRIDGIGPAPYSYVVDLVVDGTHHTGTGTFAGGSGGGDSRITFDPPLPAS
>NZ_CP040695.2|WP_137291943.1|2052438_2052825_+|metal-sulfur-cluster-assembly-factor
MADTQPDHSDLPEVPEATAGGSGGTATVTVDDVTEAMKDVVDPELGINVVDLGLVYDLHLDPSSNLVIDMTLTSAACPLTDVIQDQTNQALEGLVNDVAINWVWMPPWGPDKITDDGREQLRALGFNV
>NZ_CP040695.2|WP_138875749.1|2051987_2052446_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MDLDNLYQDIILDHAKRRLNAGLREPFEAEVHHVNPTCGDEVTLRLHLDGTGDEARIADISYDNQGCSISTASASVMTELLIGKTVVQAQPVHAAFLEMMRGKGQVEPDEDVLEDGIAFAGAAKLTARIKCALLSWMAYQDALIQAQEAQHG
>NZ_CP040695.2|WP_148240542.1|2050718_2051984_+|SufS-family-cysteine-desulfurase
MHGLLPELEVVRKDFPILERTLANGQALVYLDSANTSQKPQCVIDAMVDHLEHHNANIARAMHQLGAEATEAFEGGRDKVAAFLGAPSRDEVIFTKNASEALNLVANTLAWRGRHQVGEGDEVVITEMEHHSNIVPWQMLTERTGATLRWFGLTDDGELDLSNIDELLTERTKVVSFTWVSNMLGTINPVAELTRRAHEVGAIVVVDASQAAPQLCIDLAAMAPEERPDVVVFTGHKVVGPTGIGVLWGSSELLGELPPFLGGGEMIETVTMARSTYAPIPHKFEAGTPPIAEAVGLGAAVDYLSHLGLDAIRDHEHAITTHALEGLATVPGLKVLGPLDAARRGGAISFEIDGVHPHDVAQVLDSRGVAVRAGHHCAKPAHARFGVQSSTRMSSYLYTTPGEIDALVEALEYTRTYFKLG
>NZ_CP040695.2|WP_137291946.1|2049918_2050677_+|Fe-S-cluster-assembly-ATPase-SufC
MSTLEIKDLHVSVTTEDGPKEILKGVTLTIGDGETHAIMGPNGSGKSTLAYSVAGHPKYQVTGGSVLLDGVDVLEMSVDERARAGLFLAMQYPVEVPGVSVTNFLRTAKTAIDGEAPKLRTWVKDVNKSLADLDLDPSFAQRSVNEGFSGGEKKRHEIAQLELLDPKIAILDETDSGLDIDALKVVSEGVNRYRAREGKGVLLITHYTRILRYIQPDRVHVFVAGRVAESGGPELADELEANGYERFLTATV
>NZ_CP040695.2|WP_148240979.1|2059309_2060362_-|S-adenosylmethionine:tRNA-ribosyltransferase-isomerase
MLEEHPTTVFTPPPGAFAPAPAEARGVARDATRLLVASRHGTAHARFRDLADHLEPGDLVVVNNSATVAGQLDARSSRHGAVVVHLATPLDDGTWVVEVRSAPDAARAVLGAEPGDVVTAAGLGLELLEPHPRDGSSPTGRGNRLWRARADGDVVRTLERHGRPIAYGYLDRGYPLPDYQTIFASRPGSAEMPSAARPFTTDLVTRLVSKGVGVVPVTLHTGVSSQEAGEAPQAERFEVTDATARAVNAARAGGGRIVAVGTTVTRALESAVSDAGRLEARAGWTTRVVTPGAPPHVVTGLVTGWHDPAASHLLLVEAVAGAALSQVAYDAAVAGGYLWHEFGDAALFLP
>NZ_CP040695.2|WP_138875754.1|2060364_2061048_-|SDR-family-NAD(P)-dependent-oxidoreductase
MPVALVTGGSAGLGRALVHTLGARGWTVVTDGRDHARLAAAVGTLPAVVPVVGDVADPAHVEALAREVGWLGRLDLLVHNASTLGPLPLRPLRETSTEELLDVWRVNAAAPVALTRAVLPQLRTASGVVVSLSSDAAVEHYETWGAYAAGKAALDHLTLTLAAEEDLTAYAVDPGDMRTAMHQDAFPGEDISDRPLPETVVPQLLALLAARPPSGRYRAASFAQVPA
>NZ_CP040695.2|WP_138875755.1|2061165_2061984_+|enoyl-CoA-hydratase/isomerase-family-protein
MTTDTGAPISPDRLAAARLRLEVDGAVATITLDRPEVRNAQTPTMWRTLAEIGAWLPDEVRVVVVRGAGATFSAGLDRTLLTPGGGDGQERVADLLTLDEEAFSRTVGEYQEGFTWLRDPRFVSIAAVRGHAIGAGFQLALSCDLVLAADDATFCMKEAALGLVPDLTGTKPLVDAVGYSRALEICATARNVGAEEAVRIGIAIDAVPGDALDARLAQLVTALTAPLPGAVRETKALLLGATDRDLDTQRRLEREAQGRRFRELAALLGGQQ
>NZ_CP040695.2|WP_148240980.1|2062030_2063947_+|ATP-binding-cassette-domain-containing-protein
MGGGAAWRSLRTDRSVVDNRVSRQTIRRVLGFARPHRRLIAVFLTLTVVDAATVVVTPLLVQRVVDDGIIAGDRGVVLGVALAMAGFAVFSAVLSVFAGWFSSRIGEGLIFDLRTRVFAHVQRQSLAFFTRTQTGALVSRLNNDVVGAQRAFTSVLSSTVSNSIAVVVVGIAMLALSWQVTILCLLMFPVLFGVSRWVGARLAGLTRRQMDGNADLGNAMTERFNVGGAMLLKLFGRRSEEDTLFGEKASVVRDLGVRISLITRIFGATMMLVPALATALVYGVGGYLAIEGTLTVGTLLALATLLLRLLGPLQGLSNVRVDVMTALVSFERVFEVLDLPSLIKQKHDAVVLPPTAGRLEFEHVSFSYPRAEDVSLGSLEKVARKESREQAQVLTDVGFVAEPGEMIALVGPSGAGKTTVTHLVARLYDVQGGAVRVGGHDVRDVTLQSLEDVVGYVTQDAHMFHDTIGANLRYARPAATDEEIWDALDAAQVGRLVRSLPDGLDTVVGDRGYRLSGGERQRLAIARLLLKSPAIVVLDEATAHLDSESEAAVQRALDAALEGRTSLVIAHRLSTVRNADQILVLDDGRIVEFGTHTDLLRRGGLYAELYRTQFAQHDERPDPRHEVDGGADLVPTDA
>NZ_CP040695.2|WP_137291935.1|2063939_2065436_+|MFS-transporter
MPDAAAPTAPGLALTSGPGRWVLLATILGSALAGIDATVVNVALPALGDDLDADFAALQWTVTAYALTLASFILLGGTLGDRFGRRRVFVVGVVWFALASLACGLAQDVGTLIAARAVQGVGAALLTPGSLAILQVSFRPADRARAIGAWSGLGGVATAIGPLLGGWLVDTVSWRWVFLVNLPLAVVVVWLAARHVPETRDPAAAGTPIDWTGGLVGALALAGATYALIESGGRAAVVAGVVGALAAVAFVLRERRARYPILPLEVFRTAQFSAVNAVTFLVYGGFGVVFFLLVVQLQEVAGFGPVAAGSALLPVTALMLLLSSRSGALAARIGPRLQMSLGPLVAAGGLLLLSRIDADAGYLADVLPGVVVFGLGLAIMVAPLTAAALGAAPDEHVGMASGVNNAVARTGGLIALAAVPVLAGVTDGVGDGFARALWISAGVLLLAGVLAALTVRNDVLEPDDPAPPDEGVQHLPHCAVGGPPLATATDGGGRPCTG
>NZ_CP040695.2|WP_148240545.1|2065453_2066212_+|SDR-family-oxidoreductase
MDLGLTDRVYVVTGGARGLGRATADVLVAEGARVVLSGRSAETLDAARERLGADAVATVVADNADPDTPARLAASARDAWGRLDGALVSVGGPPRGPVTDVTDDQWRTAFESVFLGAVRLGRELATELGESGSLAFVLSSSVRSPLPDMALSNGLRPGLAMVAKTLADEVGPRGVRVNGLLPGRVGTERVAELDAASGDADAARAAALRTIPLGRYGEPAEFGRAAAFLLSPAASFVSGVMLPVDGGMLRAL
>NZ_CP040695.2|WP_137291933.1|2066097_2067024_-|SURF1-family-protein
MHSYRFLLSRRWLLFGLTVVLLSTFAWWLGEWQFGRLEDRKDRNAAVRANEDQDPTPVEDVLAPPGGDLPRDEEWRVVTATGTYDVDDTVIVRYRTRDGQAGVDVVVPLVTAGGTAVVVNRGWLATENRGTASPDDVPAPPSGEVTITGWARVDGTGDSIAVEDQSTRAINSERIGAALSRDVYGGFVNLRSEDPPAATTLEQTELPELDNGPHFFYGLQWWFFGVLALFGFGYLAYDEHRRGPRGERPHREPRPRRTNVPAGSQRRDAVAQSARSMPPSTGSMTPDTNDAAGDSRNAAARPNSAGSP
>NZ_CP040695.2|WP_138875757.1|2067060_2068077_+|GTP-3',8-cyclase-MoaA
MQVIAPTVLPVTPLADGYGRVATDLRVSLTDKCNLRCTYCMPAEGLDWMASDQQLTDDEVVRLVTVAVERLGVREVRFTGGEPLVRRGLVDIVARTHALGVETSLTTNGLGLARTAPALAAAGLDRVNVSLDTVRAETFHTITRRDRLHDVVAGLQGAADAGLGPVKVNAVLMRGVNDDQAGELLAWCVERGYELRFIEQMPLDAQHGWSRDGMVTADEILATLEQSFVLTPDGEPRGSAPAERFLVDGGPATVGVIASVTRPFCGDCDRVRLTADGQVRTCLFAREESDLRGALRAGAPDDELARRWVTAMRGKLAGHGIDDPSFLQPQRPMSAIGG
>NZ_CP040695.2|WP_138875758.1|2068059_2068296_-|acetone-carboxylase
MEPDTCSAKGCRAPATWQLLWNNPKLHTPERRKTWLACDDHRGSLEQFLGARGFLKDTVPHVLGSESGASQDPSAADR
>NZ_CP040695.2|WP_137291930.1|2068296_2068623_-|DUF3099-domain-containing-protein
MARTRAGTDDTVRITTAAGSRAAEIRSRQKRYLLSMSLRTLCFVGAVIASLSGVDWLWPILVAGAIVLPYIAVVMANAAANLSDGFRLREGDFTRPELGASTRRDREL

Crispr_ID: NZ_CP040695_12

• CRISPR_ID: NZ_CP040695_12
• CRISPR_location: 2725862-2725966
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_12

Consensus_repeat	Method
CCCAGCCACCGGACGTCGAGCAGCG	CRISPRCasFinder

spacers of NZ_CP040695_12

>12.1|2725887|55|NZ_CP040695|CRISPRCasFinder
CGCGTCAGAGAGACCGGACGTCGAGCAGCGAGCGCCAGCGAGCGTCGACGAGGCG

CRISPR arrays and Neighbor proteins around NZ_CP040695_12

CRISPR arrays

The CRISPR arrays of NZ_CP040695_12

>merge|NZ_CP040695|12|2725862-2725966|CRISPRCasFinder
CCCAGCCACCGGACGTCGAGCAGCGCGCGTCAGAGAGACCGGACGTCGAGCAGCGAGCGCCAGCGAGCGTCGACGAGGCGCCCCACCACCGGACGTCGAGCAGCG

>NZ_CP040695|12|12|2725862-2725966|CRISPRCasFinder
CCCAGCCACCGGACGTCGAGCAGCG	CGCGTCAGAGAGACCGGACGTCGAGCAGCGAGCGCCAGCGAGCGTCGACGAGGCG
CCCCACCACCGGACGTCGAGCAGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138876094.1|2731957_2732956_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224054
NZ_CP040695.2|WP_138876089.1|2726678_2727533_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138877156.1|2722454_2723861_+|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|235798
NZ_CP040695.2|WP_138876095.1|2732952_2733945_+|ABC-transporter-permease-subunit	unknown	unknown	unknown
NZ_CP040695.2|WP_138877157.1|2729339_2730059_+|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl|CDD|184638
NZ_CP040695.2|WP_138876090.1|2727619_2728528_+|TIGR01777-family-protein	unknown	unknown	gnl|CDD|187553
NZ_CP040695.2|WP_138876086.1|2719287_2720388_-|glycine-cleavage-system-aminomethyltransferase-GcvT	unknown	unknown	gnl|CDD|234742
NZ_CP040695.2|WP_138876085.1|2719033_2719291_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876084.1|2718104_2718935_-|PhzF-family-phenazine-biosynthesis-isomerase	unknown	unknown	gnl|CDD|223461
NZ_CP040695.2|WP_138876082.1|2716502_2716748_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137292844.1|2721965_2722298_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137292620.1|2716790_2717270_-|dihydrofolate-reductase	unknown	unknown	gnl|CDD|365932
NZ_CP040695.2|WP_148240655.1|2723887_2725783_+|2-oxoglutarate-dehydrogenase,-E2-component,-dihydrolipoamide-succinyltransferase	unknown	unknown	gnl|CDD|200219
NZ_CP040695.2|WP_138876093.1|2730674_2731877_-|inorganic-phosphate-transporter	unknown	unknown	gnl|CDD|376541
NZ_CP040695.2|WP_137292627.1|2726149_2726608_-|tellurite-resistance-TerB-family-protein	unknown	unknown	gnl|CDD|377455
NZ_CP040695.2|WP_138876092.1|2730076_2730358_-|DUF3349-domain-containing-protein	unknown	unknown	gnl|CDD|371747
NZ_CP040695.2|WP_138876087.1|2720451_2721969_+|leucyl-aminopeptidase	unknown	unknown	gnl|CDD|234863
NZ_CP040695.2|WP_137292634.1|2730354_2730660_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876083.1|2717269_2718076_-|thymidylate-synthase	unknown	unknown	gnl|CDD|234984
NZ_CP040695.2|WP_138876091.1|2728508_2728838_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138876094.1|2731957_2732956_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.77954e-86
NZ_CP040695.2|WP_138877156.1|2722454_2723861_+|dihydrolipoyl-dehydrogenase	gnl|CDD|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP040695.2|WP_138876084.1|2718104_2718935_-|PhzF-family-phenazine-biosynthesis-isomerase	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	5.02016e-79
NZ_CP040695.2|WP_138876090.1|2727619_2728528_+|TIGR01777-family-protein	gnl|CDD|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.73973e-87
NZ_CP040695.2|WP_138877157.1|2729339_2730059_+|lipoyl(octanoyl)-transferase-LipB	gnl|CDD|184638	PRK14345, PRK14345, lipoyl(octanoyl) transferase LipB.	2.20122e-114
NZ_CP040695.2|WP_138876086.1|2719287_2720388_-|glycine-cleavage-system-aminomethyltransferase-GcvT	gnl|CDD|234742	PRK00389, gcvT, glycine cleavage system aminomethyltransferase GcvT.	0
NZ_CP040695.2|WP_138876093.1|2730674_2731877_-|inorganic-phosphate-transporter	gnl|CDD|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	8.30826e-88
NZ_CP040695.2|WP_137292620.1|2716790_2717270_-|dihydrofolate-reductase	gnl|CDD|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	2.78213e-64
NZ_CP040695.2|WP_148240655.1|2723887_2725783_+|2-oxoglutarate-dehydrogenase,-E2-component,-dihydrolipoamide-succinyltransferase	gnl|CDD|200219	TIGR02927, putative_dihydrolipoamide_acyltransferase, 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase. This model represents an Actinobacterial clade of E2 enzyme, a component of the 2-oxoglutarate dehydrogenase complex involved in the TCA cycle. These proteins have multiple domains including the catalytic domain (pfam00198), one or two biotin domains (pfam00364) and an E3-component binding domain (pfam02817).	0
NZ_CP040695.2|WP_137292627.1|2726149_2726608_-|tellurite-resistance-TerB-family-protein	gnl|CDD|377455	pfam05099, TerB, Tellurite resistance protein TerB. This family contains the TerB tellurite resistance proteins from a a number of bacteria.	1.38094e-27
NZ_CP040695.2|WP_138876087.1|2720451_2721969_+|leucyl-aminopeptidase	gnl|CDD|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	1.53296e-168
NZ_CP040695.2|WP_138876083.1|2717269_2718076_-|thymidylate-synthase	gnl|CDD|234984	PRK01827, thyA, thymidylate synthase; Reviewed.	0
NZ_CP040695.2|WP_138876092.1|2730076_2730358_-|DUF3349-domain-containing-protein	gnl|CDD|371747	pfam11829, DUF3349, Protein of unknown function (DUF3349). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 99 to 124 amino acids in length.	4.47246e-35

Protein sequences

>NZ_CP040695.2|WP_148240655.1|2723887_2725783_+|2-oxoglutarate-dehydrogenase,-E2-component,-dihydrolipoamide-succinyltransferase
MATEVNLPALGESVTEGTVTRWLKQVGDTVAVDEPLLEVSTDKVDTEIPSPVAGTLLEIKAQEDDTVEVGAVLAVIGDEGESAGDADESAAPEAQPKDEGEAEKKAEQEEEIVEEKGDLPAGDETPEKEKPAEDAPAASGGGEATSVTLPALGESVTEGTVTRWLKSVGDDVAVDEPLLEVSTDKVDTEIPSPVAGTLLEIKVEEDETVEVGAELAVIGDKGASAADVSGSAAPEAQPKDDGEAEKKAEQEEEIVEEKGELPAGDETPEKEKAPEPEKKPEPENPQAPTDAPTSSKEQAPAPSAQSPSTGESSEGSSDGGSYVTPLVRKLAAQHNVDLASVSGSGVGGRIRKQDVLDAASAAKEAAAAPAAAAPAAPAASSSAPAAQAPSVTPSPLRGTTEKISRLRKIIAERMVDSLQSGAQLTQVVEVDVTNVARLRNAKKEEFLAREGVKLSYLPFFTKAAVDALKQHPKLNATIDTDEGTITYYDRENIAFAVDTEKGLLTPVVKDAGDLSIAGLAKKIADVAGRTRANKIGPDELGGGTFTITNLGSVGALWDTPIINKPQVAIMGPGAVVKRAVVIDDPNLGETIAVRHMVYLALTYDHRLVDGADAGRFLQDVKKRLESGVFEV
>NZ_CP040695.2|WP_138877156.1|2722454_2723861_+|dihydrolipoyl-dehydrogenase
MGRTRVADFDVLVLGAGSGGYACALRAAQLGLSVGLVEKDKVGGTCLHVGCIPTKALLHAAEVADSARESEQFGVRATLDGIDMPGVNAYKDGVVSRLHKGLAGLIKGRGITVLEGAGTVTGPRQVTVAGEVHTGRHLVLASGSYPRTLPGLDVDGERVLTSEHALRLERVPASVIVLGGGVIGSEFASVWRSFGAEVTIVEALPRLVAGEDEASSKALERAFRKRGISFRTGTRFQSLERTDGGVAVTVTSGDDGARTDVLEAELLLVAVGRGPATDGLGLEELGVTTERGFVLTDDHCRTNVEGVYAVGDIVPGLQLAHRGFQQGIFVAEHIAGLDPVPVDETGIPRVTYSHPEVASVGLDEAAARTAYGDDGIETVTYDLGGNGKSQILKTQGFVKLIRRTDGPVVGVHLVGDRVGELIGEAQLIYNWEAHAEDVAPLVHAHPTQNEALGEAHLALAGKPLHAHS
>NZ_CP040695.2|WP_137292844.1|2721965_2722298_-|hypothetical-protein
MSRPTGGQRTGSTTVRAADRVDEQHLHEFVEARRGVEGFVEPRTAVSEVTLLLVAHDGEWTRRRVPSVAWAHDFANKHQVPSYDAAVVGVPQRMRDYNSRIKAERRERGL
>NZ_CP040695.2|WP_138876087.1|2720451_2721969_+|leucyl-aminopeptidase
MTTYTLRSASPAKTRADAVVVGVLSGDSRPSLAPGGEDVLDAYGRRLAPLLASLGVTGKAGEVVKVPTSKAIASPVLVLVGLGPSVTATSVRRGAGAAARAVTNAASVAVALPADSPELVRAATEGYLLGGYTFTAYKKQSSTSTAPGEVVVLSPASRKKDVAAAFEEAQVLARAVAGVRDWVNTPPNDLRPPSFADAVVAANKARGRGAATITVKVLDEEQLAELGCGGILSVGAASDAPPRLVELSYAPQGATTHLALIGKGITFDTGGLSIKPAANMHEMKSDMAGAAAVVQATFAIADLGLPLKVTTYASLAENMLGGSATRPGDVVTMYGGTTVEVLNTDAEGRMVLGDALVMASEKEPDVMLDVATLTGHMVVALGDRVGGVLGDDDVVAAVMAAATVAGEDHWPMPIPEFMDERIHSSRIADLAQHDWIRWGGGLYAAAFLREFTGGLPWAHLDIAGPAYNSGGPTGHLTSGGTGVAVTTLVEYARTLSEHGLPARGA
>NZ_CP040695.2|WP_138876086.1|2719287_2720388_-|glycine-cleavage-system-aminomethyltransferase-GcvT
MSELLRSPLHDRHEALGAKFAEFGGWSMPLEYAGVVAEHHAVRSAVGIFDVSHLGKAEVRGPGAAAFVDATLSNDLARIGPGQAQYTLCCDDATGGIVDDLIAYHRGEESVFLIPNAANTAEVVRRLQAAAPDGVEVENQHRDHVVLAVQGPSSDEVLAAVGFPVGHDYMSFVEAPFGESRVVVCRTGYTGERGYELVAPNDVAVALWDSLMAAGAAYGIAPCGLGSRDTLRTEMGYPLHGQDISLDVTPNEARLGWAVGWRKEAFWGRDVLVAEKERGPRRRLFALESTGRAIPRPHMSVSLTPDVLLGEVTSGTFSPTLRKGIALALLSTVVNPEAQVGVDVRGRRELFQIVKLPFVDSSVRDA
>NZ_CP040695.2|WP_138876085.1|2719033_2719291_-|hypothetical-protein
MNPPEAPPTFRRPSVEERPWAWRLEDAAGTEVGVEGDLADQRFANQADAESWVGETWADLAALGVDQVVLFEHDRRVYGPMSLHA
>NZ_CP040695.2|WP_138876084.1|2718104_2718935_-|PhzF-family-phenazine-biosynthesis-isomerase
MHALRQVDVFSAEPLLGNPVAVVHDADDLTEEQMAAFARWTNLSETTFLLRPSDPAADYRLRIWTPGGELPFAGHPTLGSAHAWLEAGGVPAAAERVVQECGAGLVDVRRGDRLAFAAPPLTRSGPVDRADLDHAVRVLGLQRADVVDAAWIDNGPGWMGLLLPDAATVLDCRPDFGAFDGLKVGVVGPHRDDSECAVEVRAFCPGYGPAEDPVTGSLNAGVAQWLAGSRLPASYVAAQGTVLGRRGRVHVELAGDVVWVGGDTRTTISGSVGLSR
>NZ_CP040695.2|WP_138876083.1|2717269_2718076_-|thymidylate-synthase
MRAYLDLVQRILDEGVEKDDRTGTGTRSVFGHQMRFDLTEGFPLVTTKKVHTRSVFAELLWFLRGDTNVGWLQDRGVTIWDEWADADGDLGPVYGYQWRSWPTPDGQHVDQIAQVVEQIRTNPDSRRHLVSAWNVADVPRMALAPCHTMFQFYVAPSEGGGRLSCQLYQRSADVFLGVPFNIASYALLTHMVAQVTGLEVGDFVHTLGDAHLYSNHLDQARLQLTREPRPLPRLVLDPSVTALDEFDLEHVRVEGYDPHPGIRAPIAV
>NZ_CP040695.2|WP_137292620.1|2716790_2717270_-|dihydrofolate-reductase
MKRVILVAAVARNGVIGNGPDIPWSLPGEQAEFKKLTLGHTLVMGRTTYESIGRPLPGRTTVVLTRDPSWSPGRDDVLVARSVLDALARAATREGEVIVAGGAQVYAAAMPLASEQVITEVPLEPEGDVHYPPIDPRVWREADRERFDGYERAWYERVT
>NZ_CP040695.2|WP_138876082.1|2716502_2716748_-|hypothetical-protein
MASYDADLQAAVDATSVARDAGIAAEADLVGYLRQQLAEREVETADEAWLQRTVEAIIADPNYMIETEPNDFVSQRKQQDG
>NZ_CP040695.2|WP_137292627.1|2726149_2726608_-|tellurite-resistance-TerB-family-protein
MPSFWAKLRQSTEGMQQQLLAKKNDLQSGGFRDASMAMCALVAAADGSIDESERQKVSSLITSNEALGNFPPESLRAKFDEACAKLTADYQLGKVELIQVISKTKKKPAEARAVIQIGIIIGGADGTFDDQEKAVVREACHAVGIDPSEFEL
>NZ_CP040695.2|WP_138876089.1|2726678_2727533_-|hypothetical-protein
MKRPLAVLCVASLVPLLAACGDDPEPGDGPVVEVQEQGAEPRARLVIDVEVGHTETTVMTLDQDVDAGQSVDVPPIEMTLTNEVVSVDGDAIRVDTTYGESRVADQDDPAAADIEAALSELTGVTGSTTFTPSGEVTDSEIDIPDGVTSTVRQSMEQLTDQSSSLTVAFPEEELGAGATWTASSALELNGIEVQQTTSYELVSLEGDQYVIEVEVTQEFEPGEAEGFEVVSGDGTSTGTMRGTVGNLTASEVTTSGRTDIRVEAGGQEQTVSTETEMTVRTTVD
>NZ_CP040695.2|WP_138876090.1|2727619_2728528_+|TIGR01777-family-protein
MSLTVVLAGGSGFLGAHLKQELRARGHEVVSLVRRDTSARDESTWDPYAGTLDRTLVRSAAVVVNLAGSPTLGNPHSKRWARELRSSRVTTTRLLAETIAQAATPPAYLAGNGISYYGDHGDQVLTEVSDTRGHALLTSVTREWQAATEAAVAGGSRVCVLRTAPVMDRRAAPLQQLRLLTRAGLGGRLGKGRQYMPMSTLRDWVGAVVHLAEHPDAAGPFNICLPQAPTNAEFTRALGRALHRPTFLPVPAPAIRLAGGAMAPELLGSLNVRPAALLDSGFVFADADVEACLATALSASDD
>NZ_CP040695.2|WP_138876091.1|2728508_2728838_-|hypothetical-protein
MAWTTGDTAALARLYTGRSVAGRRDVAMLEAWNARGRRVTEMSTQVLALEVVASGRGRLVLEVTDRLARAVAGGTELPADRVSTRRLVLRPGGGDAGWRVSAVLSRPTR
>NZ_CP040695.2|WP_138877157.1|2729339_2730059_+|lipoyl(octanoyl)-transferase-LipB
MSFRVAGLAPDAVDYLAAWDLQREVHAGVVAGAPGTVLLLEHPPVYTAGKRTEQHERPADPGGADVVDVDRGGKITFHGPGQLVGYPIVRLPDHVKVVDYVRRVEEALIAVCRDLGVETARVPGRSGVWLRAGHGRPERKVAAIGIRVSRGVTMHGFSLNCDVDLGWYDRFVPCGIADAGVTTLSVETGRRVTVADVLPAVEAHLRHYLAWGPYTSTPDYDPRPEPGRTPRIELVRPGA
>NZ_CP040695.2|WP_138876092.1|2730076_2730358_-|DUF3349-domain-containing-protein
MTGPLSRVVAWLREGYPAGVPAQDYVPLLALLRRRLSDEEVVEIARELEEAGLAPHDHADIAVSISKVTDAMPSAADVDRVREHLAFRGFPRD
>NZ_CP040695.2|WP_137292634.1|2730354_2730660_-|hypothetical-protein
MENIGFALEGAWQVLLIGLLLGAGLPAVFALGIRSLAHGAGGAAETVQGGHAAPHPVGRLGAAVCFAVVLAGVALGITIVVASGFGKEVSFENVVPSLVDK
>NZ_CP040695.2|WP_138876093.1|2730674_2731877_-|inorganic-phosphate-transporter
MTPELVILGLVVVTALAFDFTNGFHDTGNAMATSIATGALRPRVAVALSASLNLVGAFLSVEVALTVTNAVIKIQDTDGAPRPEFLADGGEALLVIVLAGLVGGILWNLATWLLGLPSSSSHALFGGLVGATIAGLGFHGVNWAGDGTKLDGVVGKVILPALLSPLIAIAVAAVGTWLIHRITEGVAERYRESGFRWGQIGSASLVSLAHGTNDAQKTMGVITLALLASGEWSDTTSIPLWVKVSCAVAIALGTYLGGWRIIRTLGKGLVEISSPQGMAAESSSAAVILTSSHLGFALSTTHVATGSILGTGVGKKGAEVRWGVAARMALAWLVTLPMAAVVGAVAWYAAHLVGGLPGAVAVFVVLVAASGAMYVRSRREPVDHDNVNADWDGMPTQAKV
>NZ_CP040695.2|WP_138876094.1|2731957_2732956_+|ATP-binding-cassette-domain-containing-protein
MARHATTGGGTVTDLVIEAAGLRKEFRGRRGVRVAVENLDLAVPGGGVHGFLGPNGSGKTTTIRMLLGLARATRGEMRLFGQPVPESLPAVIDRVGAVVESPKFSPHFTGRQNLLLLSRSIGAPDTRVDAAIETVGLTGRDGDRFKSYSLGMKQRLAIAATLLKDPQLLILDEPTNGLDPAGIREIRDTIRDLGERGVTVLLSSHILAEVQQVCTSATIIGNGRLLASGRVEDLLDTGAAAHAVEVADPDTATRVLSGAGLTVAATPTGLRVESDDPAAITRILGEAGVWLSALTPLRRDLESVFLELTAADTLGHEHLDGADGLGRKGGAA
>NZ_CP040695.2|WP_138876095.1|2732952_2733945_+|ABC-transporter-permease-subunit
MTGLLRVELTRLRWRRAVLVLVGAAVLVPLVILGVRTYDTRPVGDGDRAAAQQQVDVELEYIEQGIADCEQNPRNFGVDPDRAERQCARQFGYQPQVEDYLYREQLNVARERSNSALAVVAIVAALMLLAGTTYVGHDWNSGSMSNQLLFEPRRLRVWLAKAVAVALVAASVAVVGLVLFWGGLLLVAQSRDLPVPGQVVTDVVQHALRSTLAITGAAVFGYALTTLSRSTVFTIGVLFAVSVAGGLIFALLPQSALRYEPSTNAAAVVNGRAEYWVQPPEACYGPRVPDGLDCDETKEVSVQHGTAYYAVLMLLVGGASAASFRRRDIS

Crispr_ID: NZ_CP040695_13

• CRISPR_ID: NZ_CP040695_13
• CRISPR_location: 3310558-3310633
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_13

Consensus_repeat	Method
CGGCGAGCGCCGACGAAACCCCGG	CRISPRCasFinder

spacers of NZ_CP040695_13

>13.1|3310582|28|NZ_CP040695|CRISPRCasFinder
AACCACCGGAGGTTGAGCAAGCGAGCCT

CRISPR arrays and Neighbor proteins around NZ_CP040695_13

CRISPR arrays

The CRISPR arrays of NZ_CP040695_13

>merge|NZ_CP040695|13|3310558-3310633|CRISPRCasFinder
CGGCGAGCGCCGACGAAACCCCGGAACCACCGGAGGTTGAGCAAGCGAGCCTCGGCGAGCGCCGACGAAACCCCGG

>NZ_CP040695|13|13|3310558-3310633|CRISPRCasFinder
CGGCGAGCGCCGACGAAACCCCGG	AACCACCGGAGGTTGAGCAAGCGAGCCT
CGGCGAGCGCCGACGAAACCCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_137293923.1|3308436_3308997_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP040695.2|WP_137293793.1|3303917_3304097_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876400.1|3308975_3310520_+|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_CP040695.2|WP_148240745.1|3311815_3312835_-|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NZ_CP040695.2|WP_137293922.1|3304777_3305101_-|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|274340
NZ_CP040695.2|WP_137293794.1|3304115_3304739_+|hypothetical-protein	unknown	unknown	gnl|CDD|236642
NZ_CP040695.2|WP_148240746.1|3315259_3318196_-|vitamin-B12-dependent-ribonucleotide-reductase	unknown	unknown	gnl|CDD|235828
NZ_CP040695.2|WP_138876403.1|3313656_3315162_+|SIR2-family-protein	unknown	unknown	gnl|CDD|238697
NZ_CP040695.2|WP_138876402.1|3312913_3313660_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|226596
NZ_CP040695.2|WP_138876398.1|3306250_3306919_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137293807.1|3321043_3321415_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876396.1|3301786_3302551_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137293921.1|3303258_3303903_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NZ_CP040695.2|WP_138876397.1|3302582_3303248_-|SprT-family-zinc-dependent-metalloprotease	unknown	unknown	gnl|CDD|370932
NZ_CP040695.2|WP_138876399.1|3306937_3308239_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876404.1|3319090_3319585_-|mismatch-specific-DNA-glycosylase	unknown	unknown	gnl|CDD|381679
NZ_CP040695.2|WP_138877191.1|3311435_3311819_+|DNA-mismatch-endonuclease-Vsr	unknown	unknown	gnl|CDD|238136
NZ_CP040695.2|WP_137293804.1|3318366_3318849_-|transcriptional-repressor-NrdR	unknown	unknown	gnl|CDD|234774
NZ_CP040695.2|WP_138876401.1|3310660_3311257_-|dual-specificity-protein-phosphatase-family-protein	unknown	unknown	gnl|CDD|350348
NZ_CP040695.2|WP_138876405.1|3319671_3320964_+|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl|CDD|224883

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_137293923.1|3308436_3308997_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	2.07315e-11
NZ_CP040695.2|WP_148240745.1|3311815_3312835_-|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	1.3115e-43
NZ_CP040695.2|WP_138876400.1|3308975_3310520_+|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.73116e-91
NZ_CP040695.2|WP_137293922.1|3304777_3305101_-|TraR/DksA-family-transcriptional-regulator	gnl|CDD|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	8.79346e-19
NZ_CP040695.2|WP_137293921.1|3303258_3303903_-|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	2.01687e-06
NZ_CP040695.2|WP_148240746.1|3315259_3318196_-|vitamin-B12-dependent-ribonucleotide-reductase	gnl|CDD|235828	PRK06556, PRK06556, vitamin B12-dependent ribonucleotide reductase; Validated.	0
NZ_CP040695.2|WP_138876403.1|3313656_3315162_+|SIR2-family-protein	gnl|CDD|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	1.32921e-26
NZ_CP040695.2|WP_138876402.1|3312913_3313660_+|NUDIX-hydrolase	gnl|CDD|226596	COG4111, COG4111, Uncharacterized conserved protein [General function prediction only].	3.04219e-07
NZ_CP040695.2|WP_137293794.1|3304115_3304739_+|hypothetical-protein	gnl|CDD|236642	PRK10030, PRK10030, YiiX family permuted papain-like enzyme.	0.00204298
NZ_CP040695.2|WP_138876397.1|3302582_3303248_-|SprT-family-zinc-dependent-metalloprotease	gnl|CDD|370932	pfam10263, SprT-like, SprT-like family. This family represents a domain found in eukaryotes and prokaryotes. The domain contains a characteristic motif of the zinc metallopeptidases. This family includes the bacterial SprT protein.	1.88761e-09
NZ_CP040695.2|WP_138877191.1|3311435_3311819_+|DNA-mismatch-endonuclease-Vsr	gnl|CDD|238136	cd00221, Vsr, Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches.	7.31543e-27
NZ_CP040695.2|WP_138876404.1|3319090_3319585_-|mismatch-specific-DNA-glycosylase	gnl|CDD|381679	cd10028, UDG-F2_TDG_MUG, Uracil DNA glycosylase family 2, includes thymine DNA glycosylase, mismatch-specific uracil DNA glycosylase and similar proteins. Uracil DNA glycosylase family 2 consists of thymine DNA glycosylase (TDG), which removes uracil and thymine from G:U and G:T mismatches in double-stranded DNA. It includes mismatch-specific uracil DNA glycosylase (MUG), the prokaryotic homolog of TDG. Escherichia coli MUG is highly specific to G:U mismatches but also repairs G:T mismatches at high enzyme concentration. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil in DNA can arise as a result of misincorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other..	1.03841e-45
NZ_CP040695.2|WP_137293804.1|3318366_3318849_-|transcriptional-repressor-NrdR	gnl|CDD|234774	PRK00464, nrdR, transcriptional repressor NrdR.	1.97403e-73
NZ_CP040695.2|WP_138876401.1|3310660_3311257_-|dual-specificity-protein-phosphatase-family-protein	gnl|CDD|350348	cd14498, DSP, dual-specificity phosphatase domain. The dual-specificity phosphatase domain is found in typical and atypical dual-specificity phosphatases (DUSPs), which function as protein-serine/threonine phosphatases (EC 3.1.3.16) and protein-tyrosine-phosphatases (EC 3.1.3.48). Typical DUSPs, also called mitogen-activated protein kinase (MAPK) phosphatases (MKPs), deactivate MAPKs by dephosphorylating the threonine and tyrosine residues in the conserved Thr-Xaa-Tyr motif residing in their activation sites. All MKPs contain an N-terminal Cdc25/rhodanese-like domain, which is responsible for MAPK-binding, and a C-terminal catalytic dual specificity phosphatase domain. Atypical DUSPs contain the catalytic dual specificity phosphatase domain but lack the N-terminal Cdc25/rhodanese-like domain that is present in typical DUSPs or MKPs. Also included in this family are dual specificity phosphatase-like domains of catalytically inactive members such as serine/threonine/tyrosine-interacting protein (STYX) and serine/threonine/tyrosine interacting like 1 (STYXL1), as well as active phosphatases with substrates that are not phosphoproteins such as PTP localized to the mitochondrion 1 (PTPMT1), which is a lipid phosphatase, and laforin, which is a glycogen phosphatase.	2.01489e-09
NZ_CP040695.2|WP_138876405.1|3319671_3320964_+|NupC/NupG-family-nucleoside-CNT-transporter	gnl|CDD|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	2.27255e-157

Protein sequences

>NZ_CP040695.2|WP_138876400.1|3308975_3310520_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MATAPGVRDTPPPDKAPDLPADYKPWPALLAMVVGFFMILVDNTIVSVATPAIMQDLRTDYNAVIWVTSAYLLAYAVPLLVTGRLGDRFGPKNVYLAGLVVFTLASLWCGLTDSIEMLILARVVQGFGAAMITPQTMAVITRTFPPAKRGGAMALWGATAGVATLVGPILGGVLVDSLGWEWIFIVNVPIGVIGFVLAWRLVPVLPTHTHSFDWLGVALSGIGVFLVVFGIQEGEKYDWGQIEGLISVPLLIVVGVVVFAAFVFWQSRIKAEPLVPLGLFRDRNFSLGNGGIALVSLGITSMSLPFFFYAQGVRGWSPTESALLMAPMAVVLMILSPFVGKLVDRTHPRNITVVGFGTAAVAMFWLSQLIEPTTPVWQLCLPMALFGVSNACLWAPLSATATRNLPMASAGSGAGVYNTTRQVGAVLGSAAIAALIQGRLTANGIEGSSQDLQAAGDTMPSFIQGPFSQAMSQTLYLPVGAFLIGLVLVLFLAKPSHAGHGRAPEAKADSVATP
>NZ_CP040695.2|WP_137293923.1|3308436_3308997_+|PadR-family-transcriptional-regulator
MTPLAVSALALLAERPMHPYEMYQLLLERHEDRFVKIRPGSLYHAVQRLEAERLVEATGTDRDGNRPERTTYAITAGGRVAMTERIREILQRPVREYPHLPLALAEAHNVPAEQVAADLRQYLAALDDDIAELADVLRAARGRGKPETYLVGGDYLLTMTTAQRDWIALLITRIDTEDFAWQPHLA
>NZ_CP040695.2|WP_138876399.1|3306937_3308239_-|hypothetical-protein
MTDMDLTAATEAAWTSFRGRLADHVAAMAGDDSLVLAVPEALGGDDDAAAPAVLVSALADGLVRLEVVLDARPDRRVTADDVRARLLERLGWPAPLDETGGEHPHQMAERREADRVAVLLVGTLREVHGVPHPAFLAAGGLEVDPGSVAWTPSAPDRPADPGPTGDVVEVPRDREHLQSMVDAAMRVVFPDLRHDADGDIPVRDGESALYVRVLPGRPVVELYAELVVDPVEADRLSLEAGLLNAAHPTWKFVHRDATVVMVHEVVAVPFVASQLRVLVDLFLDDLDRLSGELVARVGGRRFLQPLPPPAPTAEHTPDHTGDHTGEHEPDLVLAGLLELCHLGRPRAATVAGLFGHDRLELIRQIVRLRSGQQGCGEHDPDVVLTALRQALRLVSDGHVEQPTVLSPRPRSVQSSLLGDADLGEDALDLGWSA
>NZ_CP040695.2|WP_138876398.1|3306250_3306919_+|hypothetical-protein
MTTSTTHPRRRRLTAGGIGLVCGVAALSVSLGVPSEAAKLITGKDVKNSSLTGKDVKKDSLTGSDVKEKTLQGVLKSGQVAAFGDAESVSIDNFVTAAFTPVVSTAVTAPTSGVLYITGTLSSEDDITIPGSGRLQYGLSLDGSQLSDGVHALDYDNETVGNDDSGAATAVVPVSAGSHTVALTARNLGGGSFILAREVSVMFVPSGSGFTPPAKPSAPKSQ
>NZ_CP040695.2|WP_137293922.1|3304777_3305101_-|TraR/DksA-family-transcriptional-regulator
MRTALEAERRRAAERLARLRGDFDEVVAASRDTNADDEHDPEGATIAFERSQIDTLVRQARDRLAEIDAALERLAAGRHGRCEVCGQPIPAERLEVRPSARTCVGCA
>NZ_CP040695.2|WP_137293794.1|3304115_3304739_+|hypothetical-protein
MTTSRSTSLGLDEAVDLTRTGDLWLFRGRSAADHAIRVLTNAPVNHVGMAVVVDDLPPLLWHAELGKGLTDVWTGSRHRGVQLHDLREAVVQWCGRYEQRAWLRQLDTVVTAEQEAAVLRTVARLDGTPFPSTAALAGRWARGRVRRQAGVEMTYCAEVVAATYQAMGLLDDARPTNYYDPGRFWSGDDLELLGGATLGEEIAVHVP
>NZ_CP040695.2|WP_137293793.1|3303917_3304097_-|hypothetical-protein
MKLWKWLGLAGVAGVAATGAVIARDQRRRSQVTPDEVRERLHERLAESDGPDDRSGARP
>NZ_CP040695.2|WP_137293921.1|3303258_3303903_-|alpha/beta-fold-hydrolase
MVDVRTPRSPDAAVVVLHGGARRRERAVVSPTQLSVVRMIPVARSIGRAGGRRLAVVRLLNSYRGWDDERTPLDDATWAVDQLRERYGDVPVALVGHSLGGRAALLAAAHDAVRTVVALNPWVYPSDGVPLPGRRVLFVHGDADRVAPIGRARAVAERLSGSADVRFEVVPDGKHAMLRHGRVFERAASDFVVETLLDAPADETSAGGAVGGDV
>NZ_CP040695.2|WP_138876397.1|3302582_3303248_-|SprT-family-zinc-dependent-metalloprotease
MDLGDAFAMAEDLLEHHGLHDWTVELDGAKRRAGICRFGPQVLGLSAPLTTLHSEAEVRDTILHEIAHALAGPAHGHDATWRAVARRIGSSGERCVSPESPRVEPPWLGVCPAGHTTGRHRRPERVMTCAQCSRTFDLAHLITWTHHGRPAEPHPNYDAELARLRAGRRLQLLRPGTRARVIAPGEHHGRVGKVVKLGRTSYHLRAGGAVLRVPFAHVERA
>NZ_CP040695.2|WP_138876396.1|3301786_3302551_-|hypothetical-protein
MTGEDQWPVYEPGATPRTPEPRTPEEPTVARRRSPLLAVVVAACVLGGAGAAGLALLGGEPDDPPAAGAGREPADVAVDGSVDGPAVRPPPGAQPAPVPVDVLTARGYRALLAALERRTGSTEVFSVSLHATGAHLEVPVDATTRREVRISWDGRFDGPGATGTSVFHDRVDLADVDPAVFVRMGRQALRAVEDATVSHVIISGPPTSGPDDGTRVRVYAGNEYGEGGYLGATAGGSVTRRHLDRPVGGPRPTG
>NZ_CP040695.2|WP_138876401.1|3310660_3311257_-|dual-specificity-protein-phosphatase-family-protein
MTIRPDLEHANAVFVTERLLVGGDLDQRDDHLAGRQLDELVAAGLTHVIDARVEADDREFVERHAPGVTYLWHGMDDAGQRVPPAWFEAGVAWVLEALEDPDAVVLTHCHMGINRGPSLGYAVLLAQGVDPVDAIAAIRAVRPISAVAYAEDALRWHHHRSSASSSERRRDRARLRAWRQENPLDVLRIIAQQRRAGA
>NZ_CP040695.2|WP_138877191.1|3311435_3311819_+|DNA-mismatch-endonuclease-Vsr
MSRLARSRTAPEILLRRELHRRGLRFRTQVKVPGNRRRTIDIALTRAKVAVFVDGCFWHACPDHFTQPRANADWWRWKMDGNVARDRDTDELLRAAGWQVVRVWEHEDVVIAADAVQRLWRERTAST
>NZ_CP040695.2|WP_148240745.1|3311815_3312835_-|ADP-ribosylglycohydrolase-family-protein
MTSSTTARLDRAAGVLLATAAGDALGVPYEFARPPAADELAEMTGGGLGGFAPGEWSDDTAMAVAIAEVAATGADLTTDDALDAIALGFLRWYDDGPADIGVQTSAVLGATRRNLGRPGGPGGGRPAEVMAAVAATYAVEHAHSAGNGALMRTAPVALAHLEDRDRLARAARLVARLTHADPLAGDACVLWSEAIRVAVVEGRIGVRAGLDLLPADRRAPWSGWLDAALAGPAAGFTPNGYTVTALQAAVAAVAGTPDADHRHLQDALHAAVRIGDDTDTVAAIAGGLLGARWGARAVPEAWRRAVHGWPGRDGDDLLALAARAVRGDRPGNATPGDQG
>NZ_CP040695.2|WP_138876402.1|3312913_3313660_+|NUDIX-hydrolase
MSDLGDYPRPHLAVDLVILTTGALRPEDDRVSLGVLVQRRADGRAVLPGRFVRERHTVLETVRELLAEKLDFRPRRDVHLEMIDLYDAPERDERGWVVSVGHLTTLLPDDVERLSPDLVEVLPITGNAARGRRVTRESLAHDHDAMVTTAVRRARRRYERSPDPLRLARAPYTLSQLRHVHEAVLGEPLKRDTFNRRMQPFLTAATGPRGDLLVSDTGGRPAQLFRPTTARDRDPEAGPFPLPRTASR
>NZ_CP040695.2|WP_138876403.1|3313656_3315162_+|SIR2-family-protein
MSGHLFVAHGDLTRLACDAIVVPCDGAGNVSDSWAALLPPDLPRGDGPGWLRVGSPDAAGAVDLGTHAGRRVVALDTVSGAPSPADLAARTWAAVDRLGPGLTARDGRRQPLVALPLVGTGDGGLAGRRGEVVAALLERRRERTPSVDVALVLRDRRDVAAVQARRVDADWDCLPPHLRGEADRLGTLAGEGRLSLFLGAGVSMPVGLPDWWSLLGSIAAEEPVVDLAGVDDPLDAASRLVRSRGAEPFLDAVVARVSTDRHGIGHALLGGLGVRQSVTTNFDACFETALHGVRGDDVDVLTRSVADGSRPWLLKLHGDVAVPSSLVLTSEQYAVHAADHQALDGVVQALLLTSHLLFVGFSLTDANFLRLARQVDVVRAESAGARTTPSGTALALTTRDVTAAGYQGLTMLPMSPGLDRPAAGRVLEIFLDRLAWTAARAHDLSSEYLLDERYASGLSAADRVLKQHLLALAARPGVTDSEAWPEVRRLLHRLGGGADER
>NZ_CP040695.2|WP_148240746.1|3315259_3318196_-|vitamin-B12-dependent-ribonucleotide-reductase
MTETVSGASSSTQGTTNGKGHGKGLTVERVFSTPGVHPYDEVTWERRDVVQTNWKTGATVFEQRGVEYPSTWSVNASTIVTTKYFRGAVGTEAREQSLRQLIDRIVKTYTKAGADHGYFATDADTEVFEHELTWLLVNQYFSFNSPVWFNVGTASPQQVSACFILSVDDSMDSILNWYKEEGFIFKGGSGAGLNLSRIRSSKELLSSGGTASGPVSFMRGADASAGTIKSGGATRRAAKMVVLDVDHPDIVEFVETKAKEEDKIRALRDAGFDMDLGGADITSVQYQNANNSVRVSDEFMRAVEDGTDFALRGRKNGEEIERVDARGLFRKISEAAWACADPGLQYDDTINDWHTNPETGRITASNPCSEYMSLDNSSCNLASLNLLKFLKDDDTFDAALFAKAVEFIITAMDISICFADFPTEPIGETTRNYRQLGIGYANLGALLMAMGLGYDSDGGRAMAATITSLMTGQSYKRSAELAAVVGPYAGYARNADAHKRVMRKHQAANDTIRTLAIADSGVHKLATQAWAEVQKLGEANGFRNAQASVLAPTGTIGFMMDCDTTGIEPDFSLVKFKKLVGGGSMQIVNQTIPRALRKMGYQPEQVEAIVAYIGENGHVIDAPGLRLEHYEVFDTAMGARSLKPMGHVRMMAACQPFLSGAISKTVNLPESATVEEIEDVYLQSWKLGLKATAVYRDNCKVGQPLSDGKGDNKGKDSNLATDAEADETPTKVIEKVIYAPTRKRLPKSRVSRTTSFTVGGAEGYMTSGAHDDGELGEVFLKLGKQGSTLAGVMDAFSIAVSIGLQYGVPLETYVSKFTNLRFEPAGLTDDPDVRMAQSLMDYVFRRLALDYLDFDARSMLGIYSASERQRHLETGSYDLPPEETGNASELIESGVELVSPQPVTAEAEVVETKDTHGAEQREVPAKVTTTKAHTSAELLEQLTGTAVDSPLCMTCGTKMRPAGSCYVCEGCGSTSGCS
>NZ_CP040695.2|WP_137293804.1|3318366_3318849_-|transcriptional-repressor-NrdR
MHCPYCRGTDTRVLDSRVADDGGSIRRRRTCSSCERRFTTVELMQLSIRKRSGASEPFARDKAVAGVRKACKGRPVSDAQLACLGQEVEDTLRLTGAAEVPAHEVGLAILGPLRALDEVAYLRFASVYRSFESADDFIKEIAAMHAESTPSLATQPAPTG
>NZ_CP040695.2|WP_138876404.1|3319090_3319585_-|mismatch-specific-DNA-glycosylase
MEVLPDIVAAEPRVVFCGLAGAASTKLRDHYYETPGNSFWESLHLSGFSPRRLRPDEDRLVAELGLGLTDLVGHWDPRSVELDALVAKLETWRPEWIAFTSKGVAAEAARADGVRRPGLGPRDWYLGGAQVFVLPGVSGANQRHDYDGRPTRLAWWRDLAALAL
>NZ_CP040695.2|WP_138876405.1|3319671_3320964_+|NupC/NupG-family-nucleoside-CNT-transporter
MADLRGVLGLAVLLLVAWLLSKDRRGVSWRTVGVALALQVGFAVLVLRWGPGERALGWVSERVESLIGYANEGTAFVFGPLLDVGEEGSTIFALQVLPVIIFLGTLIGLLYYLRVIQWTTYLVGGALSKLLGIGKVESLYAGTVVFLGMSEAPLMVQGYLGRLRQGQVFAIMTAGFAAAAGSTLVGYSLLGAPLEYLLAATVMNAPASILMAKLMWPDSVADPDPDPDPDPDPDADQEAHGDRDGAEEIDVRDVRDEESANVIDALGRGAMAGGRIAVTVGALLIAFVAVIALANGILGGVGGWFGAEDLTFEKILGWAVAPLAWLLGVPWSEAADAGSWIGQKTVLNEFVAYADFGPQVGDLSPVTVAVVTFALAGFANFSSIAIQIGALGSLMPERRAMVARLGLRALLAGSLANLANAAIAGVVVGL
>NZ_CP040695.2|WP_137293807.1|3321043_3321415_+|hypothetical-protein
MAHGKRAGARTKRRLRPALLGLALGVTLAVVAWGYLVYAAIDFGTSARAGDSTAWWFLALAALGAVACLFLGLVLVTRISRAVGLTRGPDPRTPATPAEPAGPTAAPGPGGAPPTPGGRRAAR

Crispr_ID: NZ_CP040695_14

• CRISPR_ID: NZ_CP040695_14
• CRISPR_location: 4102880-4103286
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NZ_CP040695_14

Consensus_repeat	Method
GACCGGCTCCGGCGACCTCCACATCG	CRISPRCasFinder

spacers of NZ_CP040695_14

>14.1|4102906|28|NZ_CP040695|CRISPRCasFinder
CCGGCACCATCGGCACCTGCCACCTGCG
>14.2|4102960|28|NZ_CP040695|CRISPRCasFinder
AGGACGTCGCCGGCGCGGGCCTGGTGGA
>14.3|4103014|28|NZ_CP040695|CRISPRCasFinder
TCTCGGTCACCGGGTCGCTGCGCGTCAA
>14.4|4103068|28|NZ_CP040695|CRISPRCasFinder
GCACCGCGGGCAGCGACGCCGCGGTCTC
>14.5|4103122|28|NZ_CP040695|CRISPRCasFinder
GCGAGTCGAACGGCGCCACGGCCGTCAA
>14.6|4103176|28|NZ_CP040695|CRISPRCasFinder
GCCAGGCCCGCACCGACGTCGGCCTCAC
>14.7|4103230|31|NZ_CP040695|CRISPRCasFinder
CCTCGGTCAGCGCCGGCCGGGTGCAGGTCAA

CRISPR arrays and Neighbor proteins around NZ_CP040695_14

CRISPR arrays

The CRISPR arrays of NZ_CP040695_14

>merge|NZ_CP040695|14|4102880-4103286|CRISPRCasFinder
GCTCGGCAGCGCCGACCTGCACGTCACCGGCACCATCGGCACCTGCCACCTGCGGTCGGGCTCCGGCGACGTGCGCGTCCAGGACGTCGCCGGCGCGGGCCTGGTGGAGACCGGCTCGGGCGACATCACCCTGGTCTCGGTCACCGGGTCGCTGCGCGTCAAGAGCGGCTCCGGCGACGTCACGATCGGCACCGCGGGCAGCGACGCCGCGGTCTCGACCGGCTCGGGCGACGTCCAGATCCGCGAGTCGAACGGCGCCACGGCCGTCAAGACCGGCTCCGGCGACCTCCACATCGGCCAGGCCCGCACCGACGTCGGCCTCACGACCGGCTCCGGCGACCTCCAGATCGCCTCGGTCAGCGCCGGCCGGGTGCAGGTCAAGGGCGCCTCGGGCGACGTCCGCGTCG

>NZ_CP040695|14|14|4102880-4103286|CRISPRCasFinder
GCTCGGCAGCGCCGACCTGCACGTCA	CCGGCACCATCGGCACCTGCCACCTGCG
GTCGGGCTCCGGCGACGTGCGCGTCC	AGGACGTCGCCGGCGCGGGCCTGGTGGA
GACCGGCTCGGGCGACATCACCCTGG	TCTCGGTCACCGGGTCGCTGCGCGTCAA
GAGCGGCTCCGGCGACGTCACGATCG	GCACCGCGGGCAGCGACGCCGCGGTCTC
GACCGGCTCGGGCGACGTCCAGATCC	GCGAGTCGAACGGCGCCACGGCCGTCAA
GACCGGCTCCGGCGACCTCCACATCG	GCCAGGCCCGCACCGACGTCGGCCTCAC
GACCGGCTCCGGCGACCTCCAGATCG	CCTCGGTCAGCGCCGGCCGGGTGCAGGTCAA
GGGCGCCTCGGGCGACGTCCGCGTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_148240890.1|4104817_4105393_-|dCTP-deaminase	unknown	unknown	gnl|CDD|234753
NZ_CP040695.2|WP_138876819.1|4101934_4102510_+|toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|226679
NZ_CP040695.2|WP_137294062.1|4106519_4107176_+|DUF2461-domain-containing-protein	unknown	unknown	gnl|CDD|378166
NZ_CP040695.2|WP_138876818.1|4100024_4101755_-|sodium/solute-symporter	unknown	unknown	gnl|CDD|271372
NZ_CP040695.2|WP_148240888.1|4099069_4099711_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP040695.2|WP_137294049.1|4090615_4091365_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|377092
NZ_CP040695.2|WP_137294063.1|4107269_4108055_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_134766511.1|4108130_4108589_-|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224870
NZ_CP040695.2|WP_138876817.1|4093260_4094829_-|histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
NZ_CP040695.2|WP_138876821.1|4105443_4106223_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238870
NZ_CP040695.2|WP_148240891.1|4108832_4110707_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173842
NZ_CP040695.2|WP_138876814.1|4088507_4089305_-|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|130643
NZ_CP040695.2|WP_138876823.1|4110814_4111693_-|ArgP/LysG-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|235144
NZ_CP040695.2|WP_148240887.1|4091572_4093264_-|urocanate-hydratase	unknown	unknown	gnl|CDD|235448
NZ_CP040695.2|WP_138876815.1|4089331_4090084_-|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270256
NZ_CP040695.2|WP_138876824.1|4111763_4112363_+|LysE-family-transporter	unknown	unknown	gnl|CDD|224198
NZ_CP040695.2|WP_148240889.1|4099729_4100011_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876816.1|4090121_4090517_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|273189
NZ_CP040695.2|WP_137294058.1|4103517_4103697_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137294059.1|4103709_4104651_-|siderophore-interacting-protein	unknown	unknown	gnl|CDD|99790

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138876819.1|4101934_4102510_+|toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|226679	COG4226, HicB, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	0.000344117
NZ_CP040695.2|WP_137294062.1|4106519_4107176_+|DUF2461-domain-containing-protein	gnl|CDD|378166	pfam09365, DUF2461, Conserved hypothetical protein (DUF2461). Members of this family are widely (though sparsely) distributed bacterial proteins, about 230 residues in length. All members have a motif RxxRDxRFxxx[DN]KxxY. The function of this protein family is unknown.	4.7955e-66
NZ_CP040695.2|WP_138876818.1|4100024_4101755_-|sodium/solute-symporter	gnl|CDD|271372	cd11478, SLC5sbd_u2, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	0
NZ_CP040695.2|WP_148240888.1|4099069_4099711_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.70563e-15
NZ_CP040695.2|WP_137294049.1|4090615_4091365_+|ABC-transporter-permease	gnl|CDD|377092	pfam03649, UPF0014, Uncharacterized protein family (UPF0014).	4.14585e-51
NZ_CP040695.2|WP_134766511.1|4108130_4108589_-|Rrf2-family-transcriptional-regulator	gnl|CDD|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.36844e-37
NZ_CP040695.2|WP_148240890.1|4104817_4105393_-|dCTP-deaminase	gnl|CDD|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	2.85822e-96
NZ_CP040695.2|WP_138876821.1|4105443_4106223_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	6.01668e-65
NZ_CP040695.2|WP_148240891.1|4108832_4110707_+|acyl-CoA-dehydrogenase	gnl|CDD|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.85406e-176
NZ_CP040695.2|WP_138876814.1|4088507_4089305_-|molybdate-ABC-transporter-permease-subunit	gnl|CDD|130643	TIGR01581, Molybdenum_transport_system_permease_protein_modB., NifC-like ABC-type porter. This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way. Included in this group is a gene designated NifC in Clostridium pasturianum. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity.	4.61538e-70
NZ_CP040695.2|WP_138876823.1|4110814_4111693_-|ArgP/LysG-family-DNA-binding-transcriptional-regulator	gnl|CDD|235144	PRK03635, PRK03635, ArgP/LysG family DNA-binding transcriptional regulator.	1.2029e-126
NZ_CP040695.2|WP_137294059.1|4103709_4104651_-|siderophore-interacting-protein	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	6.8556e-65
NZ_CP040695.2|WP_138876815.1|4089331_4090084_-|molybdate-ABC-transporter-substrate-binding-protein	gnl|CDD|270256	cd13538, PBP2_ModA_like_1, Substrate binding domain of putative molybdate-binding protein;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins of putative ABC-type transporter. Molybdate transport system is comprised of a periplasmic binding protein, an integral membrane protein, and an energizer protein. These three proteins are coded by modA, modB, and modC genes, respectively. ModA proteins serve as initial receptors in the ABC transport of molybdate mostly in eubacteria and archaea. After binding molybdate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.8349e-80
NZ_CP040695.2|WP_138876824.1|4111763_4112363_+|LysE-family-transporter	gnl|CDD|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	7.28195e-61
NZ_CP040695.2|WP_138876816.1|4090121_4090517_-|MerR-family-transcriptional-regulator	gnl|CDD|273189	TIGR00638, Probable_molybdenum-pterin-binding_protein, molybdenum-pterin binding domain. This model describes a multigene family of molybdenum-pterin binding proteins of about 70 amino acids in Clostridium pasteurianum, as a tandemly-repeated domain C-terminal to an unrelated domain in ModE, a molybdate transport gene repressor of E. coli, and in single or tandemly paired domains in several related proteins. [Transport and binding proteins, Anions].	5.38052e-11
NZ_CP040695.2|WP_138876817.1|4093260_4094829_-|histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NZ_CP040695.2|WP_148240887.1|4091572_4093264_-|urocanate-hydratase	gnl|CDD|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0

Protein sequences

>NZ_CP040695.2|WP_138876819.1|4101934_4102510_+|toxin-antitoxin-system-HicB-family-antitoxin
MDITPYVDHLRRDLLAAAEGAGDELRNAAERLSFALDPAARLALMEAISQACAEITAEMPAGGVDVRLDGRDLAFVVDSAAAQHLAGPPAPPAPPTPPLPPAPPEEAEDGGMARITLRLPESVKARAEDAAAGAGQSLNTWLVNVIRSATRGQGDAAINVDIDLSSLPFFGGDGFPNTRGNRGSKRMNGWV
>NZ_CP040695.2|WP_138876818.1|4100024_4101755_-|sodium/solute-symporter
MSSVLPMATIIDANFVDYLIVGIYFAFVLGIGVMARRQVSDSVDFFLSGRSLPAWVTGLAFVSANLGAVEIMGMSANGAEFGLPTLHYFWIGAIPAMLFLGVVMMPFYYGSKVRSVPEFMLRRFGPAAHLVNALSFAVAQLLIAGINLYLLASIIKAMLGWELWISLVVAAVVVLTYITLGGLSAAIYNEVLQFFVIVAALLPLTLIGLHQVGGYSGLKDKITEAAPTAADADAQLNSWPGTNLTGIDNEVLSVIGIVLGLGFVLSFGYWTTNFVEVQRAMASDSISSARKTPIIGAFPKILVPFITILPGMIAAVAVAEIVQTKAGETVAGGASGDGVKFNDSLLYLMRDVLPNGLLGIAIAGLLAAFMAGMAANISAFNTVFSYDLWQSYAVKDRSDGYYLKVGRLATIGATVVAIFTAGLAANFDNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPTAAWIGLVAGTLSAVAVAFLSEDAFGSASLGVIGLSGQGASFVAAGAAFAVDIVLSVVISLVTKPRPASELVGLVYSETPKDTLVDENEAGYPWYRRTVPLAGVALGLVVVLNFIF
>NZ_CP040695.2|WP_148240889.1|4099729_4100011_-|hypothetical-protein
MAQPTGSKKHTAGALDIRNVIGALLFVYGAILLVTRLVSGDEGGENSAGVNANLWAGLALAAVGAGFMIWSRVRPIVVPEHVDSPEDLTPPKR
>NZ_CP040695.2|WP_148240888.1|4099069_4099711_+|GNAT-family-N-acetyltransferase
MLADIWPTYGLRVRTGRLCLRLPDLDELAALAELAGRGVHGPEERPFLTPWTDGTPTERAARVLRGHWSQLHAWRPEDWSLGLCVFLDDRPVGAVSLRARDFRVVREVTTSSWLGVEHQGAGLGTEARVGLLTLAFDHLGALDATTEVFPDNRASQGVSRRLGYLPDGISRDARGEEALVSDRLRLTAARWAGQQHPDVTVEGVDAARAMFLG
>NZ_CP040695.2|WP_138876817.1|4093260_4094829_-|histidine-ammonia-lyase
MTASSRPALDAVVVGTGPVSFADVVAVARGGAPVVIGEDALTAIDRARAVIEELAAGATPAYGVSTGFGALATRHIPTEMRAQLQRSLVRSHAAGSGPEVEREVTRALMLLRLSTLATGHTGVRRETAQLLAGLLTHGITPVVHEHGSLGCSGDLAPLSHCALALMGEGPVRDASGALVDAATALAAVGLEPVELAAKEGLALINGTDGMLGMLVLAIEDLRRLLRTADVAAAMSVEGQLGTDRVFAAELQALRPHPGQAASAANLVRLLADSGVVASHRGPDCNRVQDAYSLRCAPQVHGAARDTLEHAATVAGRELCAAVDNPVVLPDEGRVESNGNFHGAPVGYVLDFLAIAAADVASMSERRTDRFLDRNRSHGLPPFLADDPGVDSGHMIAQYTQAAIVSELKRLAVPASVDSIPSSAMQEDHVSMGWSAARKLRHSVDGLTRVVAVEVLTAARALDLRAPLVPSPATAAVVALLRSSGVAGPGPDRHLAPEIEAAVTLVASGAVVTAVEEVIGELQ
>NZ_CP040695.2|WP_148240887.1|4091572_4093264_-|urocanate-hydratase
MTPSVNPANPRLPIRAVRGTDLTARSWQTEAPLRMLMNNLDPENAERPEDLVVYGGTGKAARDWPSYDALVRTLTTLGDDETMLVQSGRPVGVMRTHAWAPRVLIANSNLVGDWANWEEFRRLEDLGLTMYGQMTAGSWIYIGTQGILQGTFETFAAVADKRFGGTLAGTITLTAGLGGMGGAQPLAVTMNDGVAICVEVDQARITRRIEHRYLDEQADSVEDAVARAVAARDARRPLSIGLLGNAAEIFPLLLEMDAPIDVVTDQTSAHDPLSYLPVGVGVDDWADAADRDPAGFTKDAQASMAAHVRAMVEFQDKGAEVFDYGNSIRDEARKGGYDRAFEFPGFVPAYIRPLFCEGRGPFRWAALSGDPADIAATDRAILELFPAHESAQNERLHKWITMAGERVAFQGLPARICWLGYGERHLAGLRFNEMVASGELSAPVVIGRDHLDCGSVASPYRETEAMLDGSDAIADWAILNALVNTASGATWVSFHHGGGVGMGRSLHAGQVCVADGTELAAAKIERVLTNDPGMGVIRHVDAGYDRAVEVAVERDVRVPMREA
>NZ_CP040695.2|WP_137294049.1|4090615_4091365_+|ABC-transporter-permease
MSTVADHALFGLGLLVLCGSTLALARWARLDLGWFPLWALVRATVQLSAIALILSGVLAAPATVAAFLVLMVSTASLTAAGRLKGLRHGRRVAVLGVVVGSAVTLALVLALGLVDLEARYVVAVAGIVIGNTMSAATLTGRHFLHDTRQRRDEVEAWFALGASPSQAHDEIGRTAVREALLPNLDQTKSTGLVTLPGAFVGALFGGADPVEAAQFQLVVLAGLGLAMTTTGVIVARLAGRTPYLPEQDG
>NZ_CP040695.2|WP_138876816.1|4090121_4090517_-|MerR-family-transcriptional-regulator
MTTYRVSEAAGLLGVSDDTLRRWIDAGRVVADTSTGRAEIAGADLAALAVSLADDPDRESTRAAHVSARNRLAGIVVAVKKDVVMAQVDMVCGPYRLVSLMSAEAADELGLEPGSRVVASVKSTNVVVETP
>NZ_CP040695.2|WP_138876815.1|4089331_4090084_-|molybdate-ABC-transporter-substrate-binding-protein
MRRTALLAAAFLLAPALAACGGDDEGTTLNVYAAASLTATFEEVAEVFEQEHDGVDVELNFSGSSDLVTAIQEGADADVFASADLPNMDKITTDGLEAGDPVDFATNTLQIVVPPGNPAGVTGFADLAGADVKLVVCAPEVPCGAATQKVSENTGITLSPVSEEQSVTDVLGKVTSGEADAGLVYVTDVIAAGEAVEGIEFPEAAEVVNTYPIVVLADSEEGDLAQEFVDLVLGEAGQGVLGDAGFAPAP
>NZ_CP040695.2|WP_138876814.1|4088507_4089305_-|molybdate-ABC-transporter-permease-subunit
MVTARARPTGLPGWVFVPAALGAVFVLLPLVAIVARVDWANFVPLITSDSSRAALWLSLRTSAVSTVLCVLLGVPMAVVLARTEFRGQGVLRSLVLLPLVLPPVVGGLALLYTFGRRGLLGETFSAWGIEIAFSSTAVVMAQTFVSMPFLVVSLEGALRTAGQRYEVVAATLGAGPSTVFRRVTLPLVLPGLLSGAVLAFARALGEFGATVTFAGSLQGTTQTLPSLIYQERVTDPDAAVALALVLVVVAVVVIGLARQGRGSTR
>NZ_CP040695.2|WP_137294058.1|4103517_4103697_+|hypothetical-protein
MNNATQLLDYELRRNHSAVLATGLTGQDRARTDLLSARRQTRRRRMAQRVRAVADRLDA
>NZ_CP040695.2|WP_137294059.1|4103709_4104651_-|siderophore-interacting-protein
MTTTTTDLPMLIEEVECVSVERVSPSFVRVELGSPALAELDRNDRSYDQRVKLIFADGDHPLPSFAGADDSWYATWMTKPLSERGHMRTYTVREVRGEGVDTRLVVDFIVHDGDCGPGGTWGARARVGDRLVLMAPRRGYLYGGIEFVPGDASRLLLVGDETAVPAIAAILEQLDVGAQGAAFLEVPFSDDVLTLQHPPGISVHWVPRDGAPRGEALDVAVLGYLGAGPVDLDVSDDEVDPDLWETPTHSSSGEDVAEHAGPVGHDWDGLYAWIAGESKIVTGLRRALVKDLGIDRHQVAFMGYWRHGVAMRS
>NZ_CP040695.2|WP_148240890.1|4104817_4105393_-|dCTP-deaminase
MLLSDRDIMAEIDAGRVGLDPWDPGMVQPSSVDVRLDRYFRVFENHRYPHIDPAADQSDLTRVVEPQGDEPFILHPGEFVLGSTYEVVSLPDDIAARVEGKSSLGRLGLLTHATAGFVDPGFSGHVTLELANVATLPIKLYPGMKIGQFCFFRLSSPSEHPYGSEKYGSRYQGQRGPTPSRSFQSFHRTPI
>NZ_CP040695.2|WP_138876821.1|4105443_4106223_+|SGNH/GDSL-hydrolase-family-protein
MSTHPYRRYVALGDSFTEGVGDLHPGRPNGVRGWADRVAEVLGHDEPAFGYANLAIRGRKLRAIIAEQVGPAVDLEPDLVTIYAGGNDILRPQVDLDALVADYDAALGRLAATGARLLVWTAFDPGGSATFKLLRGRFALYNELVRESADRHGASIVDFWRMREYRDWGLWDPDRLHMGPAGHQRMATAVLDVLGVPHELAPLAPTPLATSDRRADVLRQNAVWVRTSAAPWVHRRLTGRSSGDGLAPRHGTFSRPVAD
>NZ_CP040695.2|WP_137294062.1|4106519_4107176_+|DUF2461-domain-containing-protein
MQFQGFPVAALDFYDDLEMDNTKSFWEAHKEVYDESVKKPFAALSAALEPEFGAVKIFRPYRDVRFAKDKTPYKTHQGAFVAAGPSMGWYVELSPRGVRVGAGFYEASGARLGAIRAAVADDRTGPALRRVVSKLERSGFELGGDRLKTTPRGFDADHPRIDLLRHRQIILGRPYGFEKVIHTPAVLTLIRDDWRALKPLVTWLQRAVAGVPEDLRVR
>NZ_CP040695.2|WP_137294063.1|4107269_4108055_+|hypothetical-protein
MPRKRQAFVHVGLDDGSGDVVGTALDSHAHALLDLGVRRPAEPAEGDGTWAGLRRDAGRGRDTVVLSRPLLAAAPPDRARTLVAALDAFDVHVVVTARAPDAWTIPGDPGRDLASVLDRWAAAVPDPGRLHVIVGSDGAGTWRSFGRVVGFGTASLRVGPETPSVTSGQDVVPAARAADLRRLAGTWADLLASSPYDVVGDLAALEPDLRCADSVDDLTAALDLARHEVELLRRRADDLERQLAKSEKKKRKLKRRLSEVA
>NZ_CP040695.2|WP_134766511.1|4108130_4108589_-|Rrf2-family-transcriptional-regulator
MRVSAKSDYALRALIEMAGREDGKAVSAEELGRLQEIPHGFLQAILADLRRAGVVMSQRGQSGGWRMGRPATDVSVADVIRAVDGPLVSVYGLRPESVTYNESADVLQHVWIAARRSLRDVFEQVSIQQLADGKLPKAVTSRTADEDAWQPH
>NZ_CP040695.2|WP_148240891.1|4108832_4110707_+|acyl-CoA-dehydrogenase
MSHYKSNLRDIEFNLFEVLGRDEILGTGPFADVDGESARSILAEVERLSREDLAASYEDSDRNPPVFDPATNTAPIPESFQKSYRAWMDAEFWRLQINEDLGGTPAPSSLVWATAEMVLGANAPVWMYAAGPAFAQVVHRNGNDRDKRIAQIMVERQWGCTMVLTEPDAGSDVGAGRSRATANADGSWNIEGVKRFITSAEHDMSENIMHLVLARPVGVEGVGGPGTKGLSLFLVPHHHFDHETGELTGERNGVYVTNVEHKMGIKVSNTCEVTFGDSSVGNGEPARGWLLGEVHHGIAQMFQVIENARMMVGTKAIATLSTGYLNALEYAKQRQQGADLTQSGDKTAPRVTITHHPDVRRSLMVQKSFSEAMRSLVLYTATWQDRIQLAEHHGEGLGEDAKLANAVNDLLLPIVKGYGSERSWVLLGTESLQTFGGSGFLQEYPLEQYVRDAKIDTLYEGTTAIQGQDFFFRKIVKDQGRALGTIAAEIQKFLDAEGGNGRLKSERALLATALDDANAIVGHMINELMSAQDDIRNIYKVGLNTTRLLMVLGDVVCAWLLLRGADVALGKLGGEVSPKDKSFYEGKVAAAQFFAQYNLPKISAERAIAEATDLSLMDLDESAF
>NZ_CP040695.2|WP_138876823.1|4110814_4111693_-|ArgP/LysG-family-DNA-binding-transcriptional-regulator
MQPDQLAALAAIVDHGTFEAAARQLHVTTSAVSQRIRALETSVGQVVVRRSTPCVATPAGETLVRLARQTALLHDEARALLDAGTRARTDLPVAVNADSLATWFRDVVGEVAGWDGVALRLHVEDQGFSADLLRRGDVLGAVTSDPVAVQGCAVEPLGSLRYRPAASPAFAERWRHGRGADWARMPVVVFNEKDALQHELLAARGLGPPPVAHRVPTSTDYHEAVRRGLGWGLLPAPQLDPDLASGALVLLSARDRVDVPLHWQRWRLDSPVLARLTETVRAAAAPALRPAR
>NZ_CP040695.2|WP_138876824.1|4111763_4112363_+|LysE-family-transporter
MLSSSVAGLLTGLSLIIAIGAQNAFVLRQGLARRHVGAVVAVCAVSDLVLIVAGIAGIGTVIEQAGWVVDVVRWAGVAFLTWYGVRSLLRARRGESLEAATGQDATLGVAVRTAVALTWLNPHVYLDTVLLVGSIAHTHDHVWWFAAGAGTASIVWFVGLGYGARLMHRTLSTPRAWQVLDVLIGVTMLGIAALLATGG

Crispr_ID: NZ_CP040695_15

• CRISPR_ID: NZ_CP040695_15
• CRISPR_location: 4173177-4173284
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_15

Consensus_repeat	Method
CGGCCCGCCGGGATATTCACCGCTG	CRISPRCasFinder

spacers of NZ_CP040695_15

>15.1|4173202|58|NZ_CP040695|CRISPRCasFinder
GAGCGGTGAAACTCGCGCTCCTGGCATGAAACTTCGCACCACAAGCAGGAGTTTCAGC

CRISPR arrays and Neighbor proteins around NZ_CP040695_15

CRISPR arrays

The CRISPR arrays of NZ_CP040695_15

>merge|NZ_CP040695|15|4173177-4173284|CRISPRCasFinder
CGGCCCGCCGGGATATTCACCGCTGGAGCGGTGAAACTCGCGCTCCTGGCATGAAACTTCGCACCACAAGCAGGAGTTTCAGCCGACCCGCCGGGATATTCACCGCTG

>NZ_CP040695|15|15|4173177-4173284|CRISPRCasFinder
CGGCCCGCCGGGATATTCACCGCTG	GAGCGGTGAAACTCGCGCTCCTGGCATGAAACTTCGCACCACAAGCAGGAGTTTCAGC
CGACCCGCCGGGATATTCACCGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138876864.1|4163817_4164339_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876865.1|4164374_4165256_-|transglutaminase-family-protein	unknown	unknown	gnl|CDD|224224
NZ_CP040695.2|WP_138876860.1|4159653_4160610_-|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223512
NZ_CP040695.2|WP_138876863.1|4162790_4163411_-|DUF4878-domain-containing-protein	unknown	unknown	gnl|CDD|372352
NZ_CP040695.2|WP_138876867.1|4171786_4173055_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP040695.2|WP_148240902.1|4167799_4171096_-|transglutaminase-family-protein	unknown	unknown	gnl|CDD|378297
NZ_CP040695.2|WP_138876862.1|4161789_4162794_-|hypothetical-protein	unknown	unknown	gnl|CDD|379751
NZ_CP040695.2|WP_138876874.1|4181677_4182193_+|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl|CDD|319971
NZ_CP040695.2|WP_138876873.1|4179521_4181246_+|ubiquinone-dependent-pyruvate-dehydrogenase	unknown	unknown	gnl|CDD|181661
NZ_CP040695.2|WP_137294809.1|4165252_4167772_-|circularly-permuted-type-2-ATP-grasp-protein	unknown	unknown	gnl|CDD|379601
NZ_CP040695.2|WP_137294821.1|4181279_4181681_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377198
NZ_CP040695.2|WP_148240904.1|4177714_4178617_-|amidinotransferase	unknown	unknown	gnl|CDD|224747
NZ_CP040695.2|WP_138876868.1|4173341_4174409_-|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|179559
NZ_CP040695.2|WP_148240903.1|4174981_4175545_-|hypothetical-protein	unknown	unknown	gnl|CDD|377417
NZ_CP040695.2|WP_138876872.1|4178728_4179427_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP040695.2|WP_138876870.1|4175555_4176257_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP040695.2|WP_137294814.1|4174419_4174989_-|dihydrofolate-reductase	unknown	unknown	gnl|CDD|223340
NZ_CP040695.2|WP_138876861.1|4160663_4161695_-|DUF2510-domain-containing-protein	unknown	unknown	gnl|CDD|372352
NZ_CP040695.2|WP_138876866.1|4171208_4171790_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378968
NZ_CP040695.2|WP_138876871.1|4176310_4177711_+|carotenoid-oxygenase	unknown	unknown	gnl|CDD|226196

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138876865.1|4164374_4165256_-|transglutaminase-family-protein	gnl|CDD|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	1.59437e-46
NZ_CP040695.2|WP_138876860.1|4159653_4160610_-|glutathione-S-transferase-family-protein	gnl|CDD|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	1.39381e-141
NZ_CP040695.2|WP_138876863.1|4162790_4163411_-|DUF4878-domain-containing-protein	gnl|CDD|372352	pfam12870, DUF4878, Domain of unknown function (DUF4878). This is a family of putative lipoproteins from bacteria. The family is probably related to the NTF2-like transpeptidase family.	2.59542e-06
NZ_CP040695.2|WP_138876867.1|4171786_4173055_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.41781e-47
NZ_CP040695.2|WP_148240902.1|4167799_4171096_-|transglutaminase-family-protein	gnl|CDD|378297	pfam09899, DUF2126, Putative amidoligase enzyme (DUF2126). Members of this family of bacterial domains are predominantly found in transglutaminase and transglutaminase-like proteins. Their exact function is, as yet, unknown, but they are likely to act as amidoligase enzymes Protein in this family are found in conserved gene neighborhoods encoding a glutamine amidotransferase-like thiol peptidase (in proteobacteria) or an Aig2 family cyclotransferase protein (in firmicutes).	0
NZ_CP040695.2|WP_138876862.1|4161789_4162794_-|hypothetical-protein	gnl|CDD|379751	pfam15887, Peptidase_Mx, Putative zinc-binding metallo-peptidase. This family has a highly conserved HHExxH motif with a highly conserved ED pairing downstream. HExxH is indicative of a zinc-binding metallo-peptidase.	6.7942e-129
NZ_CP040695.2|WP_138876874.1|4181677_4182193_+|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl|CDD|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.27637e-63
NZ_CP040695.2|WP_138876873.1|4179521_4181246_+|ubiquinone-dependent-pyruvate-dehydrogenase	gnl|CDD|181661	PRK09124, PRK09124, ubiquinone-dependent pyruvate dehydrogenase.	0
NZ_CP040695.2|WP_137294809.1|4165252_4167772_-|circularly-permuted-type-2-ATP-grasp-protein	gnl|CDD|379601	pfam14403, CP_ATPgrasp_2, Circularly permuted ATP-grasp type 2. Circularly permuted ATP-grasp prototyped by Roseiflexus RoseRS_2616 that is associated in gene neighborhoods with a GCS2-like COOH-NH2 ligase, alpha/beta hydrolase fold peptidase, GAT-II -like amidohydrolase, and M20 peptidase. Members of this family are predicted to be involved in the biosynthesis of small peptides.	1.34573e-159
NZ_CP040695.2|WP_137294821.1|4181279_4181681_+|phage-holin-family-protein	gnl|CDD|377198	pfam04020, Phage_holin_4_2, Mycobacterial 4 TMS phage holin, superfamily IV. These proteins are predicted transmembrane proteins with probably four transmembrane spans. The 1.E.40 is represented by the mycobacterial 4 phage holin, but it also contains many cyanobacterial. proteobacterial and firmicute proteins. Holins are encoded within the genomes of Gram-positive and Gram-negative bacteria as well as in those of the bacteriophage of these organisms. The primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded the enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some may catalyze export of nucleases.	1.25411e-18
NZ_CP040695.2|WP_148240904.1|4177714_4178617_-|amidinotransferase	gnl|CDD|224747	COG1834, COG1834, N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism].	3.91237e-44
NZ_CP040695.2|WP_138876868.1|4173341_4174409_-|histidinol-phosphate-transaminase	gnl|CDD|179559	PRK03321, PRK03321, putative aminotransferase; Provisional.	3.16019e-178
NZ_CP040695.2|WP_148240903.1|4174981_4175545_-|hypothetical-protein	gnl|CDD|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	0.000596442
NZ_CP040695.2|WP_138876872.1|4178728_4179427_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.32372e-32
NZ_CP040695.2|WP_138876870.1|4175555_4176257_-|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.9444e-13
NZ_CP040695.2|WP_137294814.1|4174419_4174989_-|dihydrofolate-reductase	gnl|CDD|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	2.21081e-15
NZ_CP040695.2|WP_138876861.1|4160663_4161695_-|DUF2510-domain-containing-protein	gnl|CDD|372352	pfam12870, DUF4878, Domain of unknown function (DUF4878). This is a family of putative lipoproteins from bacteria. The family is probably related to the NTF2-like transpeptidase family.	2.89869e-08
NZ_CP040695.2|WP_138876866.1|4171208_4171790_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	3.16879e-13
NZ_CP040695.2|WP_138876871.1|4176310_4177711_+|carotenoid-oxygenase	gnl|CDD|226196	COG3670, COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	3.78321e-115

Protein sequences

>NZ_CP040695.2|WP_138876867.1|4171786_4173055_+|MFS-transporter
MRRPLHGWLVAEALSLTGTRVSMIAIPLFVLEQTGSATQTGLVALAEMLPLVVLKVLGGPVIDRVGARRVAVTCDLLSLVVVAAIPLLFDLGLLSFPGFLALVAGAGALRGPGDGAKHAMVPALVTSAGIAMERATGLSSTVERTASMLGAGLAGVLVATLGAQNALLVDAATFGLSALVLSWATKGLPATSGTGGGTVVGSEPVPYLEQLREGWDFLRRDPLLLGISVMVAVTNLLDAAWSSVLMPVWSIESGEGAATLGVLFAVMSGSSALGAVCAATIAARLPRFRTYLFAFLLCGLPRFAVFVVDTPLAGVVAVFVVAGFASGFINPVLGAVMFERIPDHLVGRVSSLTSAMCWALMPLGGLVGGVLFDTGGLALAMGACGLAYLAATMLPAVDPRWRDMDRRPEPTTVASGDASVRG
>NZ_CP040695.2|WP_138876866.1|4171208_4171790_+|helix-turn-helix-domain-containing-protein
MDRTSITPEPHQLRALAHPVRLRMLGMLRVDGPATATSLATRLGLNSGATSYHLRQLAQHGFVVDDEERGNGRERWWRAAHTSTRTAGGPAGTEAGDSADAFLQAAVVVYSEWLQQAVEEGPLLPEPWRDATSFNDWIHRLTPAAARHLMRTVGEMMEAVEDDEDDPRARSVVVQVHVFPRPGQEYDAQERHP
>NZ_CP040695.2|WP_148240902.1|4167799_4171096_-|transglutaminase-family-protein
MSIKVALEHRTTYDFAEPVHVGPHVVRLRPAPHTRTPIEAYSLTVEPRNHFVNWQQDPFGNWNARLVFPEKVKTLDITVGLVADLMVINPFDFFVEEYAEHFPFTYEDSLAADLAPYLHPVEDAGAAEAFRRAQPQPDPGDGTPIITFLAGLNAAVNGEVAYSVRMEAGVQTPDETLARRIGSCRDSAWLLVALLRQHGLAARFVSGYLVQLTADPDAMVGLDGPSGPTSDFTDLHAWAEVYLPGAGWVGMDPTSSLFAGEGHIPLSATPRPSSAAPISGATDPVEVAFSFHNQVRRVHEDPRVTRPYSEAQWARVDALGAAVDQRLTDGDVRLTMGGEPTFVSRDDATTAQWSTEADGPEKRALASTLAERLRETYARGGVVHRGQGKWYPGEPLPRWNIALQWRTDGVPLWQDPSLLSDPWGPAPTAGDEAVAVERAEALARRITRVLGLPGEHLLAAHEDPLAALASEVRQPAGDRPDGAAERLDAHGLGVLDAAVDTPTGWVLPLVPGEEWTSPAWTFRRGRLVLLPGTSAAGLRLPLDAIAWRDPASPGAASYLEAGPPLEPRVPVVGVVDPEDAPTTALAVEARDGHVHVFLPPTERLDDYADLLRLVEVAARRIGCPVVLEGYGPPPDPRLTQLVVTPDPGVIEVNVQPTTSWAEQRDLTTTLYDEARRAGLTTEKFDLDGTHTGTGGGNHLTLGGRVPVDSPLLRRPDLLVSLLTYWQRHPALSYLFSGRFVGPTSQAPRFDEGRPEAAYEMEIAFAEIERLVREQRDEGLEPRPWLVDRALRHLLTDLTGNTHRAEFCIDKLYSPDSSRGRLGLLELRGFEMPPHAQMALVQALLVRSLVAMFWEQPLRAPLVRWGTRLHEDALLPHGAAADVAEVVADLRAAGIAFEEEWLAPFVEFRFPRIGVTRAGDVEVELRQAIEPWHVLGEEATGTGTARYVDSSVERLQVAVRGYDPARHLVTCNGVPLPLTPAGAGHAGGHVAGVRYRAWQPSSALHPSIEVHAPLRLDVVAVQDGGAGVSLGGATYHVVHPGGRSYDAPPVNAHEAEARRASRFEPHGHTAGVLDVAALRRAGRAAASEEYPHTLDLRRA
>NZ_CP040695.2|WP_137294809.1|4165252_4167772_-|circularly-permuted-type-2-ATP-grasp-protein
MTVLREYAAGVLQPTLDGGGGASGRYDEVVGPDGALRPSWKGLAEVAVGLRPEDLRRLDDDIRRALSDDGVTYARAGRAGERGARPAEWRLDPMPLILDAAQWTRLEVGLAQRAELLNAVLADLYGEQRLLAEGVLPPAVVLGHPGFVRPVARASARDPRPLVLAATDLGRDHRGEWRVLGDRAQAPSGLGYAMENRRVLSRVLPELYREAGLHRMEPFFSALRSALLQSAQGELPDPRVVVLTPGSRSETAYDQAFIASALGFPLVQGSDLVVRDGWVQMRVFGRLERVDVILRRVDAGWSDPLELRGDSQLGVAGLAEAVRRGRVRVVNGLGAGVLENPGLLPYMPAMCEALLGEPLRLEAVPTWWCGDPDGLGHVLDHLDDLTVLALDAPASRPSDLPRGALVEQLVAAPHRFVGQERLALSQAPTWVAPGRVAARPLTLRTFTLRYGSAYRPLVGGLVTVVEPSGDDGGRSVSSKDLWVLKSEPGAPDQGLVDVLPMTHNRASTGTVPRILADMFWFGRYAERAEDLLRLVLAAHSLAEDFRDRPRSTGAAGLEVMMGAVTRLAGPGLDDLDAEFRSVLLDGARAGSVAHALEGLRRAGSGVRDQLSLDVWRALGTIDRAAEVLQRSTHSHQVAESAGRMLTGILALQGITASMIRDPGWHMLGAGRSVERALQVVHLLTPTTTRRRGMDVDREVLNAVLLTAESSVTHRRRYRGSVRPGGVLELLLTDPDNPRSLAFALDRTLEHLARLPASTGSSRPERLAGDLRDELAGTDIATLVAIGGEARPNLAAFLEQCTGQLLRLTDAVAELHLTTGPAPRPLAALDLVDSFEVATA
>NZ_CP040695.2|WP_138876865.1|4164374_4165256_-|transglutaminase-family-protein
MRYRVRHTTTYTYDEPVTDSLGVAHLVPRSLPWQAVSGYTVAVRPAPGDVSEDLDHYGNHVTYFQLTEPHDSLVVEGLGDVDVVAPHVPEAALRTPWEALRPVREPARAGAWRAADVALASPLVDQPASAASYASTSLTPGRPVGAAVTDLMHRVHADFEYDRTATTVTSTVAHVLDARAGVCQDFAHLMLACLRGHGLAARYVSGYLATEAPAGQPRLVGADASHAWVEVWLGDDTWLAVDPTNDQRIGDRHVTVAWGRDYGDVPPLKGVIFTEARRSTMRVAVDVAPLEAP
>NZ_CP040695.2|WP_138876864.1|4163817_4164339_-|hypothetical-protein
MLVRRSARLLVPLVLGLALLQGCGGEEGPVDDGSQASVVDAPGLETAGVEVLAAAVPAAATGDQVAAALTDAGSSGATSSTPASVEADAYALDSGAVAGLLAVVADGTGEAVVLVFDDPASAQVLAAEDPAVFAAAAVERRSEALLAGNLVGYAAGDAAIGHVRRALNSLRTG
>NZ_CP040695.2|WP_138876863.1|4162790_4163411_-|DUF4878-domain-containing-protein
MILGIVGAVVALAVVAVVLILVLTGGDDDNGGGGGQDADPADTVQEFIDALKDDDCDAAAALTTGDAAEDVEECETEGTEAFDDIDFEVGESDVDGDTATVPVTVTSSGFEETASFELEKVDGDWLISSLDGDGEEPTADAPSAGSVTPDLPSDVPTDLPTDLPSDFLSDLPSDFPSEFLSEFPTDFPTDFLTDLPTDFPTDFPTE
>NZ_CP040695.2|WP_138876862.1|4161789_4162794_-|hypothetical-protein
MKAFRCRVCDNALHLENTVCVSCGTALGFSRSERALVPVDATGQYVDATGLVWHVCANLNLSGCAWLAPLQGGQCSSCDLTRTRPSDDDVVGLQHFPAAEQAKRHLLVELDTLGMKVVGKDPARGGDPENGLAFDLLSSVEENVVIGHENGVITIDLAESDDAHREKVRAQLAEPYRTMLGHFRHEFGHYAEWQLVRGDELMARCRELFGDESVDYQAELQRHYDEGPPPGWEESYISTYATMHPFEDFAETWAHFLHIADTVETAREYGLLTIAAVGAFAQFRDVVTGVWVPLSIALNQINRSMGKDDVYPFVIAPPVLDKLDFVAGLLPLDG
>NZ_CP040695.2|WP_138876861.1|4160663_4161695_-|DUF2510-domain-containing-protein
MTHGSTPPGWYDDGQGAQRWWDGSQWTEHTQGGDQQPAQPAEPEPAPASDPHSEPTRFNPAAGLGGGPSSSSATPNLDKGAGGSSPATPEHGQPAQPEQQGYGQQGYGQQPGYGQQGYGQQPGYGQQGYGQQPGYGQQPGYDQQGYGQQPGYGQQGYGQQGYGQQPAWGNQLPASSSGGGKGKLIAIIAGGAALLLVVVVLLLTVVLGGGGPEGAAKDYFEASVEGDSEEVCELTAEEPRQELLDNLEASDCGDYADKVEAQLEEFGGDFQALQDDIDFDFDVEDVEEDGDEATVKGTVKSKYTGDDPDGFRDAYGTDELEEEDDATVELVKEDGDWKVASTS
>NZ_CP040695.2|WP_138876860.1|4159653_4160610_-|glutathione-S-transferase-family-protein
MADQGTYVEQGKAFDRDMNYVPDRITRDARRPEHGPVEGELWPVEPGRYRLVAAKACPWANRSIIVRSLLGLEDVISLGLPGPTHDARSWTFDLDPGGRDPVLGIERLQEAYLKRFPDYPRGITVPAVVEESTGLLVTNDFPWITHDLFHEWREFHRADAPDLWPVDLREEMEDVMKRVFTEVNNGVYRCGFAGSQEAYDAAYERLFTALDWLEERLGTRRYLMGAAITEADVRLFTTLARFDPVYHGHFKCNRQKLTEMPNLWGYARDLFQTPGFGDTIDFEQIKQHYYVVHRDINPSGIVPAGPDPAVWLEPHGRG
>NZ_CP040695.2|WP_138876868.1|4173341_4174409_-|histidinol-phosphate-transaminase
MAHPQPRANIARIPAYVPGKPPVVRPGVTAYKLSSNENPYPPLPGVVEAATAAVATMNRYPDMGSVALYAALSERLGVPVDDIATATGSVGLIYQVVTGFCEPGDEVVYAWRSFEAYPIAVTAAAATSVQVPLLADGRHDLDAMLAAITDRTRVVLVCTPNNPTGPAVTQTELDAFLARVPEHVVVVVDEAYLEFVRMADAVDGVATYRAHPNVVLFRTFSKAYGLAGFRVGYAVSQAPIAAALRAVSLPFGVSAVAQAAAIASLAAEAELLERVDALALERTRVRDALLAQGWDIPDAQGNFVWFPLGDRAGDLAAAADAVGVTVRPFAGDGVRVSIGEPEANDRLIEAAATLR
>NZ_CP040695.2|WP_137294814.1|4174419_4174989_-|dihydrofolate-reductase
MTDRRRLVITQNITLDGSIQMLDDWFDDQLVAEDPELLAENHRQDAAADALLVGRQTFTDFRGYWRDLEDDATGIADYLGGVRKYVVTSTLADDDLDWQHSTALRGDVVEEVRALKALPGKDVVCTGSLTLLPTLVEADLVDEYRLFVHPVVQGRGTRLFPEGHRASGLRLLEARSFATGVALLRYAAH
>NZ_CP040695.2|WP_148240903.1|4174981_4175545_-|hypothetical-protein
MFPVGGVGVMLVGVAVAGVVCGLLAVVLSRRLGPVAAVAVGGLLWSIAIIGLITLLPATAAPGVVPAEGRLDTCSWDIGGPAPDGFWIFSGGQRLLNTVVFVAPGAFLVVAAARWGRAALALVPLGLALLAAYSLGIEWTQLELARIDRACDVTDIIDNVTGAVVGVGLGVVLAMILRPWRGRDRHD
>NZ_CP040695.2|WP_138876870.1|4175555_4176257_-|TetR-family-transcriptional-regulator
MARVSDQPNRPARPDEPDLRRRLLEVAADVLAEEGPSALTARRLTREAGTSTMAVYTHFGGMPALVREIVADGFDRLHARVDAVPVTEDPLADLTAMAGAYRAHALAHPHLYAVMFGATTLGGYRLTHEEQQVGMAAFGQLVAGVRRAMDAAVLRPADPASVAAQLWTALHGYTMLEQSGFHRVVEDPEGELLQPLVANLVAGLLAAPGVPGVPGSVRDSVRVPDPGPGPGPG
>NZ_CP040695.2|WP_138876871.1|4176310_4177711_+|carotenoid-oxygenase
MSRYLQDEFAPVAEELTALDLTVSGRLPAHLDGRYLRIGPNPAQDPAALAAAGYHWFLGEGMVHGVRLEDGHARWYRNRWVRPDACDFAPNTNVVQHAGRTMALVEAGAPPYELDDELDTVGRCGFAGDLRAGYTAHPHEDPATGELHAVSYSWTRGNRVDYSVLDAAGSLRHQLEIEVHGSPMMHDCALTEHHLVVYDLPVTFDIDMVAGKAPRPLRLPTRLALNRVVGRNPVSDKVVEAMTRGRGVPTQLPYSWDDDYPARIGLLPRDATDGSAVRWFDVDPCYVFHTLNAFEVPGTDEVVVDVVRHDRMFATRFDGPDEGPASLVRFTLDLASGRASEHRFDEHPQEFPRHDERLTGRRHRFGYSVGFDDGRLGDTVLKHDTVAGTTQERRLGAGRLAGEMTFVPSSPDAAEDDGVLMGYVHDLARGLSDLVLLDAGTLEDVATVHLPGRVPAGFHGSWAPAP
>NZ_CP040695.2|WP_148240904.1|4177714_4178617_-|amidinotransferase
MSELGWGRHYVAVEPTHFRVDYVINPFMDPDVQPDPALAWRQWYDMVGTLRGLGAVVDVLPQRPDAPDMVYAMNLGLGVVRPGPDGPAPHVVMSHMRYPQRRMETRSAQPWFAEHGATTSYVGRDGVGAHLEAGDAFAFGDALVVGYGPRTEELALKHLATELGVRVRGLRITHPGMYHLDLAFCPLDDRRALVCPSALDDASAAALLDLVPEPLVLTEEEALTTFCANSVVVGRTVVMPSCPDRVRAQLEAWGFEVVVVDVSEFHKGGGSIRCLTNPVDITLGRDLPLVPGGEVVLPPE
>NZ_CP040695.2|WP_138876872.1|4178728_4179427_+|GntR-family-transcriptional-regulator
MMGPMSTAPGPVGPFATLHVEHTSTVDRAAEELRRAIFEGDIESGTALREVALAESLGVSRPTIREALGTLVAEGLATREPHRGVHVSTPEAGSVRDVCRARWVLEGAGVARWLDASEEARDHVRASLRAYTDAVRAEGTYQSLNALHLAFHVSLVGLAGSPRLVAMAENLVVELKLALAQVERIARNAHDQADSHVALVRLLEDDDVDGALAFLRTHLDDAEHEIIEALRL
>NZ_CP040695.2|WP_138876873.1|4179521_4181246_+|ubiquinone-dependent-pyruvate-dehydrogenase
MPTVAATIVASLRANGVRRVYGLPGDSLNGFTDALRKEGSIAWQHVRHEETAAFAAGAEAALTGELAVCAGSCGPGNLHLINGLYDAHRSRVPVLVIAAHIPSSEIGSTYFQETHPQQLFAECSVYCEMVGDPAQMPRVLEIAMRTAVERRGVAIVVIPGDVALADAGSTRTVVVRRARPVVVPSPEELAEAATMLDHGTKVTILAGAGVEGAHDEVVALAEALGAPIVHAYRGKEFIEHDNPYDVGMTGLLGFSSGYRAMESCDVLLMLGTDFPYQQFYPDDAKVIQVDVRGEQLGRRVPLDLGLVGTVKDTAAALLPLVTRKKKRKHLESSLEHYRKTREKLDDLATDDHDRTPIHPQYVARLIDELADDDAVFIPDVGSPVVWAARYLRMNGRRRLIGSFSHGSMANAVPQAIGAQASHPGRQVVTLSGDGGLAMLLGDLITLTQQRLPVKIVVFNNSSLNFVELEMKAAGFVTFGTDLENPDLAEVATSLGVRGFRVEKPSELPGALAAAFAHDGPALVDVVTSRQELSMPPAVTAAQVKGFTLYAIRTVMSGRGDELVDLAATNRRQIF
>NZ_CP040695.2|WP_137294821.1|4181279_4181681_+|phage-holin-family-protein
MRILLRLVTTALGVAAAAWFFDGIAFTGGPRQGWAEVEHNLVPLLLVAAILGIITSFVKPLLTFLSIPLIILTLGLFLLVINAAVLMLTGALADGLGIPFRVDGFWTAVGGAIVITLVTWVVDGAFGASDDGR
>NZ_CP040695.2|WP_138876874.1|4181677_4182193_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MSLPPPREAGRYRIGVVCLGNICRSPMAHVVLEARVAAAGLADEVTVTSSGTGGWHVGDPMDPRAAATLAAAGHDGSRHRARQFATSWHDEHDLLLAMDAANLADIGGGTDRVRLFRSFDPEEPGADVPDPYYGGDRGFQEVLAMVERCSEAIVSELATSLPTSLPSSPDR

Crispr_ID: NZ_CP040695_16

• CRISPR_ID: NZ_CP040695_16
• CRISPR_location: 4226129-4226214
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_16

Consensus_repeat	Method
GGATTTCCCCGGTCGACCGGGGAA	CRISPRCasFinder

spacers of NZ_CP040695_16

>16.1|4226153|38|NZ_CP040695|CRISPRCasFinder
GTCTGAACTTGGGGGCCGATATCCCGGCCGACAAGTTC

CRISPR arrays and Neighbor proteins around NZ_CP040695_16

CRISPR arrays

The CRISPR arrays of NZ_CP040695_16

>merge|NZ_CP040695|16|4226129-4226214|CRISPRCasFinder
GGATTTCCCCGGTCGACCGGGGAAGTCTGAACTTGGGGGCCGATATCCCGGCCGACAAGTTCAGGTTTCCCCGGTCGACCGGGGAA

>NZ_CP040695|16|16|4226129-4226214|CRISPRCasFinder
GGATTTCCCCGGTCGACCGGGGAA	GTCTGAACTTGGGGGCCGATATCCCGGCCGACAAGTTC
AGGTTTCCCCGGTCGACCGGGGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138876901.1|4230666_4232175_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143404
NZ_CP040695.2|WP_148240911.1|4217454_4219047_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP040695.2|WP_138876900.1|4229357_4229915_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876896.1|4225182_4226094_-|hypothetical-protein	unknown	unknown	gnl|CDD|197317
NZ_CP040695.2|WP_138876891.1|4215502_4217449_-|biotin/lipoyl-binding-protein	unknown	unknown	gnl|CDD|227111
NZ_CP040695.2|WP_138876899.1|4228031_4229297_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173844
NZ_CP040695.2|WP_138876898.1|4226943_4228035_-|phosphotransferase	unknown	unknown	gnl|CDD|270703
NZ_CP040695.2|WP_138877251.1|4219581_4221273_-|acyclic-terpene-utilization-AtuA-family-protein	unknown	unknown	gnl|CDD|377804
NZ_CP040695.2|WP_137295184.1|4236605_4237544_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223673
NZ_CP040695.2|WP_138877250.1|4219043_4219505_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176854
NZ_CP040695.2|WP_137295185.1|4235685_4236609_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213260
NZ_CP040695.2|WP_138876902.1|4232188_4233550_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|235687
NZ_CP040695.2|WP_138876903.1|4233680_4234835_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|378117
NZ_CP040695.2|WP_138876894.1|4223667_4224096_-|hypothetical-protein	unknown	unknown	gnl|CDD|226720
NZ_CP040695.2|WP_138876892.1|4221340_4222141_-|TIGR03084-family-protein	unknown	unknown	gnl|CDD|274423
NZ_CP040695.2|WP_137295219.1|4222137_4222701_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP040695.2|WP_138876897.1|4226248_4226944_-|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP040695.2|WP_148240912.1|4234900_4235689_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223673
NZ_CP040695.2|WP_138876895.1|4224092_4225172_-|VanZ-family-protein	unknown	unknown	gnl|CDD|377417
NZ_CP040695.2|WP_138876893.1|4222797_4223658_-|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138876901.1|4230666_4232175_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP040695.2|WP_148240911.1|4217454_4219047_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP040695.2|WP_138876896.1|4225182_4226094_-|hypothetical-protein	gnl|CDD|197317	cd09083, EEP-1, Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds. Their substrates range from nucleic acids to phospholipids and perhaps, proteins.	7.87179e-16
NZ_CP040695.2|WP_138876891.1|4215502_4217449_-|biotin/lipoyl-binding-protein	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_CP040695.2|WP_138876899.1|4228031_4229297_-|acyl-CoA-dehydrogenase	gnl|CDD|173844	cd01155, ACAD_FadE2, Acyl-CoA dehydrogenases similar to fadE2. FadE2-like Acyl-CoA dehydrogenase (ACAD). Acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACAD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. ACAD's are generally homotetramers and have an active site glutamate at a conserved position.	0
NZ_CP040695.2|WP_138876898.1|4226943_4228035_-|phosphotransferase	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	8.68825e-85
NZ_CP040695.2|WP_138877251.1|4219581_4221273_-|acyclic-terpene-utilization-AtuA-family-protein	gnl|CDD|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	1.49546e-161
NZ_CP040695.2|WP_137295184.1|4236605_4237544_-|ABC-transporter-permease-subunit	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	8.61151e-30
NZ_CP040695.2|WP_138877250.1|4219043_4219505_-|SRPBCC-family-protein	gnl|CDD|176854	cd07812, SRPBCC, START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket; they bind diverse ligands. Included in this superfamily are the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, and the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), as well as the SRPBCC domains of phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of this superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	9.55789e-15
NZ_CP040695.2|WP_137295185.1|4235685_4236609_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.09536e-114
NZ_CP040695.2|WP_138876902.1|4232188_4233550_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NZ_CP040695.2|WP_138876903.1|4233680_4234835_-|ABC-transporter-substrate-binding-protein	gnl|CDD|378117	pfam09084, NMT1, NMT1/THI5 like. This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine. They are regulated by thiamine. The protein adopts a fold related to the periplasmic binding protein (PBP) family. Both pyridoxal-5'-phosphate (PLP) and an iron atom are bound to the protein suggesting numerous residues of the active site necessary for HMP-P biosynthesis. The yeast protein is a dimer and, although exceptionally using PLP as a substrate, has notable similarities with enzymes dependent on this molecule as a cofactor.	9.81161e-35
NZ_CP040695.2|WP_138876894.1|4223667_4224096_-|hypothetical-protein	gnl|CDD|226720	COG4270, COG4270, Predicted membrane protein [Function unknown].	8.02238e-15
NZ_CP040695.2|WP_138876892.1|4221340_4222141_-|TIGR03084-family-protein	gnl|CDD|274423	TIGR03084, conserved_hypothetical_protein, TIGR03084 family protein. This family, like pfam07398, belongs to the larger set of probable enzymes modeled by TIGRFAMs family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized. [Hypothetical proteins, Conserved].	8.36302e-112
NZ_CP040695.2|WP_137295219.1|4222137_4222701_-|TetR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.66938e-09
NZ_CP040695.2|WP_138876897.1|4226248_4226944_-|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	7.82203e-17
NZ_CP040695.2|WP_148240912.1|4234900_4235689_-|ABC-transporter-permease-subunit	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.40411e-41
NZ_CP040695.2|WP_138876895.1|4224092_4225172_-|VanZ-family-protein	gnl|CDD|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	3.67156e-17
NZ_CP040695.2|WP_138876893.1|4222797_4223658_-|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	4.33225e-23

Protein sequences

>NZ_CP040695.2|WP_138876896.1|4225182_4226094_-|hypothetical-protein
MGGRRGGARRRLACVVACLVTAAPLLAACDGGGDGDGPPAGGATSPAAGPDAADLPRRRLLTVATFNVLGASHTSPGGGAAEYYPPAAERIGGTMRRIRTYRPDVLGLQELQARQSAVLRRRLGDRFGYFGDLDNAVVWRRARLAVLERTTLTIPYFYDNLREMPVVVLRVRSTGDVVTVVNVHNPADVRGEVGDNRAEAVARERAFVEAERAKGRAVLLLGDLNAEEEAFCALTEGGVLVAANGGSHRSGTCRPPDDAAIDWILGAGVEFNGFHSDASAREEKVSDHPFVVATVARLRPGRD
>NZ_CP040695.2|WP_138876895.1|4224092_4225172_-|VanZ-family-protein
MGDQATNALVAIVLGSVVAVVLLVPTAAYQYRLDGRLQAKDLAVLLSGAVYGLSLWTYTLLPMPAPDSYRCRGRQLEPFGSISRIWTDVGAPDHTFQVGQVALNVLLFVPLGYYLRVIVRRGVVTAALVGLATSLLIELTQTTGVWNLYDCPYRLLDVDDLLVNTVGAVGGSLLSFVVLDRRDDTTPPLPSTVSLGRRLVGLASDVIFSVLLGGAAAAVYRGLTEHGPGDHDAAVRTAVLVGVPYVVQAVSVLAVGRTVGEHVVAVRAVPRAGGAARSPYPRRLVKLAAGATPGFALVAVAVAGAGWVATAALVGLGLLTVAHVVVAGRTEQHRGLSHVVAGLDLRIATEERLEREVHR
>NZ_CP040695.2|WP_138876894.1|4223667_4224096_-|hypothetical-protein
MSPVRTAARVLLAAVLLVAGVAHFAIAAEFLGQVPTFLPLREEIVLVSGVVELVLGAALLLPAGRHDDRRAVLGVVVAVFFVAVFPGNVWQAVDGSPSFGLDTATARVVRLLFQPLLVVWALWCTGGWEWLHRAAGRLRPHP
>NZ_CP040695.2|WP_138876893.1|4222797_4223658_-|FkbM-family-methyltransferase
MDQDIATWTPQRVDDDAWLLVRPGARRRVRQLGPPEVEASIVYQPRSARTRQGRFERAVADFLGREHSAWLLRAVGANVVLDVGGNKGQYAKSLRRNGYTGRIVSFEPVAHLVERLRELSADDPDWRIVDCALGDEDGTAEINMTPGPLSSLLPASEFGRDWAENLSRTTVEEIRIRRLADLWDDVMAGLDDPRPFLKMDTQGYDLETFRGAGDKVQQLLGLQSEVAMVPIYDGMPRLAEMLDIYEAAGFQTTGMFPVNRDRTTLRAIEFDLMMVGPAYEPEVDPS
>NZ_CP040695.2|WP_137295219.1|4222137_4222701_-|TetR-family-transcriptional-regulator
MRARLLEATVECLVERGFAGTSTTLVSERAGVSRGAQLHHFPTKNDLVVAAVEHLTVVRGAELAAAASRLPTGVRRTRAVLQVLGDHFASPVFFAALELWVAARTDEALLAAVAPLEQRVGREAHRLVVEALGADESQPGVRELVQATLDLVRGLGLATTISDDARRRGRILDEWAAVLDARLEEHR
>NZ_CP040695.2|WP_138876892.1|4221340_4222141_-|TIGR03084-family-protein
MTLLDDLLADLAAEGDRLRALVAGLDAAGWATATPAPGWSVAAQVAHLLWTDEAATLAARAHDDQGPWDALVLAAVEDPTGFVDAAALELAALPPEELLARWDGARAGLAAALRAVPDGVRMPWFGPPMAPASMVTARFMETWAHALDVHDALGVAPEVTDRIRHVAHLGVRTRGFAFAAHGVDVPDADVRVELVAPSGGTWTWGPDDAPERVTGPAHDFCRLVTQRVHRADTDLVAVGPGADAWLDVAQCFAGPPGAGRDAVTRA
>NZ_CP040695.2|WP_138877251.1|4219581_4221273_-|acyclic-terpene-utilization-AtuA-family-protein
MREMLEGSADGQGLDVLTGDYLAELTMLILGKDTMRDPRLGYARTFVRQVEDCLGLALERGVRIVSNAGGLNPAGLADALREVARGLGLDPVVAHVEGDDLRPRAGELGLAGALTANAYLGGFGIAAALRAGADVVVTGRVTDASLVVGPAVAHHGWTPTSYDELAGAVVAGHVLECGTQATGGNFSGFLSLPAGSLDRPLGFPLAEVAADGSCVVTKHDGTGGAVTVDTVTAQLVYEIQSAHYLGPDVTTRLDTVRLEQVGPDRVAVTGVRGVAPPARLKVCVNTLGGYRNTMELVLTGLDVEAKADWVRAQLDAVLTASSVTWTRTALPAADADTEEGASCLLRCTVKDADAAPVGKAFTGPLVELALGSYPGFTLTSPPGPPTPYGVYRPALVDRAAVEHTVVHADGRREVVPDPPGPLDPDPDADHVGRRPSPYPAPIDTITRRVPLGTFVHARSGDKGGDANLGLWVAHDGSPARADRVTWLTKLITPRRVRELVPEAAALPDDAIDVYVLPHLGAVNVVLRGLLGEGVAASTRFDPQAKGLGEWVRSRHVQVQEGLL
>NZ_CP040695.2|WP_138877250.1|4219043_4219505_-|SRPBCC-family-protein
MKPMGQEVSLHVDAPVAAVWALVSDVTRIGEFSPETFEARWTKGSTGPEVGATFAGHVKRNGVGPTYWSPCRVTVCEPERVFEFSVGTDAVSVNNWGYRLDPEDGGTRVTEYFRLQPALAMRVYWLLLGRLRGRTNVNGMRTTLERMRAVLEA
>NZ_CP040695.2|WP_148240911.1|4217454_4219047_-|acyl-CoA-carboxylase-subunit-beta
MTTTQGPTHREAMLEKLADLDTEHAKAVAGGGERSVQRHHERGKLMPRERIELLVDEGSAFLELSPLAGWGSDFTVGASVVTGIGVIEGVECMITANDPSVKGGASNPWTTRKVFRAAQIAEENGLPTVSLVESGGADLPTQKEIFIPGGKLFRDLTRASARKEPTIALVFGNSTAGGAYVPGMSDHTVMVRGRAKVFLGGPPLVRMATGEESDDESLGGAEMHARTSGLADHLAEDERDAIRIGRRIVARLNWRKATAPPAPGSYAEPDADPDGLLDLIPGDLKEPFDPREVIACVVDGVSRGNAAAFDEFKPLYGTSLVTGWARLHGRPVGILANARGVLFSEEAQKAAQFVQLANQSDTPLLFLHNTTGYMVGAEYEQGGIIKHGAMMINAISNSTVPHLTVVMGASYGAGNYGMNGRAFDPRFLFTWPSAKSAVMGPAQLAGVLEIVARTSAESRGETFDADGFAGVKAMVEAQIEEQSLPHFLSGMLYDDGVIDPRDTRTVLGICLSVIENKPYAGTDRFGVFRM
>NZ_CP040695.2|WP_138876891.1|4215502_4217449_-|biotin/lipoyl-binding-protein
MITRLLVANRAEIASRVFRTCRRLGIETVALHSDADADLPYVREADHVVRLPGTSPAETYLRADLVIEAAKRAGADAVHPGYGFLSENADLARAVAAVGLTWVGPSPESMEQMGSKIRAKQIMAAAGVPVLEAPAEPTEADLPLLVKASAGGGGRGMRVVRSLASLAAEVEQARAEAESAFGDGTVFVEPYVERGRHVEVQVLGTDDGVIVLGERDCSLQRRHQKVVEEAPAPGLSDATREALHAAGRAAAAAIDYLGAGTVEFLYDDEKDIFWFLEMNTRLQVEHPVTEMVHGVDLVELQLLVAEGRVVHHHAPGLDESAPVGHAIEARLYAEDPAAGYQPQSGRLTTFEVPTDGGVRVDAGFESGSEVSTHYDAMLAKVVAHAATREQAARKLASALARARIHGLTTNRDQLVAVLRDEAFLAGEVSTAFLDEHPLAVGLVGDAGAPVAAAVALAERARLARVVQHGVPVGWRNVVSQPQRTTFAAAPGADHPGEQVVEWYGGRDGYRVDGFVVVAAGPDAVVLETDGVRRTYAVAVSGAGAVDVDGPGGHTRLHVVPWFVDPADAVASGSLLAPMPGTVVRVAVEAGQQVGAGDAVLVLEAMKMQHTVKAPTSGTVTEVNVEAGAQVAAGEVLAVVETASEGDGS
>NZ_CP040695.2|WP_138876897.1|4226248_4226944_-|histidine-phosphatase-family-protein
MGVVLLVRHGQASFGTDDYDVLSENGWEQGRRLGGWFAEHEATPTALVRGDMRRHRETLEAMGERAGWSAADVVEDPAWNEFDHLAVIAGFVAAPGESGPADVGGDVRHDRRAFQRLFERATERWAAGDGSYEETYPGFVGRVRGALDRAAAASGSGRTTVVVTSGGAIAVVCAALVDPDADPATSARLWQRFNTVTVNTSITRVVVGSGGPRLLTFNEHPHLAGPLLTYR
>NZ_CP040695.2|WP_138876898.1|4226943_4228035_-|phosphotransferase
MTPPPDPQRVEGNPARPVRDEDAFDVDAVAAWIGRGPIVEVRQFAGGASNLTYLLRYDDAAGADLILRRPPAGSKARGAHDMGREHDVQQALAPVFPFVPTMVGLCTDASVIGSEFYVMEKVDGLIPRKDFQVEVSPAAASALCSDALDVLVALHAVDVAAVPTLAALGRGDGYVARQVGGWTRRFADARTDDTGDWGAVVAWLDERQPRDVGQVLVHNDFRLDNLVLDQDSLAVVGVLDWEMATVGDPLMDLGGALAYWVQADDDEVFQMFRRQPTAAPGMWTRAEVVAAYAERTGRDVDPERWRFYEVFGLFRLAVIIQQIWYRYVHRQTTNEAFAHLGGAVAYLEGRCRALVGPGPGGAA
>NZ_CP040695.2|WP_138876899.1|4228031_4229297_-|acyl-CoA-dehydrogenase
MDFAPSPRAADLTERVRAFLVEEVEPVEADYHRELAARRLDPSLGSPWEPLPVLEELKAKARARGLWNLFLPREHAGEYAARFGTDGGEGLSNVDYAPIAELTGRSAIAPVVLNCNAPDTGNMEVLLRYGTDAQRAEWLEPLLEGRIRSAFTMTEPGVASSDATTMEATAVVDGDEVVINGRKWWSTGVGHPDCRILVFMGLTDPDADRHHRHSMVLVPRDTPGVRVERMLSTMGFHDEPFGHGEVSFTDVRVPLANIVGGPGEAFSIAQGRLGPGRVHHCMRLIGLAERALELACRRSLERTAFGKPLANLGGNRERIAEARIAIDSTRLLVLHAAWKLDRGGPLEALSEVAQIKVAAPRMAQEVIDMAIQLHGGGGLSDDHPLAGAWTTARSLRLADGPDEVHRGVVARLELGKHGASR
>NZ_CP040695.2|WP_138876900.1|4229357_4229915_+|hypothetical-protein
MRTARHPVAVRLPALAALTGLATLVLGGCDADLNQTDDHDAQPDVVRAGLVDLYAGDATDPAPADVLAEGGCFADALLDAVSLDELVAAEVVDDKGQVVETLPVLDVDVAGAWVDAFTGCVDYRVAAARGAGLAGDLDAAAFLRCLDAAVPPGDVPAALVDTLTGRSDSAAATALLDAQDRCATA
>NZ_CP040695.2|WP_138876901.1|4230666_4232175_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MTDLPVLDHWIGGSLAAGTSDRTGPVYDPALGEVTKHVRYGSADDVDAAVATARAAFAGKGGWGRSSIAKRQTVMFAFRAILHERRDELAALLTSEHGKVLSDAAGEVARGIEVVEFACSMPHVSKGAYSQSVSTDVDVYSIKEPLGVVGIISPFNFPAMVPMWFFPLAIATGNTVVLKPSEKDPSVANWLAAALTEAGLPDGVLNVVHGDKEAVDRLLVHPDVASISFVGSTPIARHVYETGTRHGKRVQALGGAKNHMLVLPDADLDLAADAAVNAGFGSAGERCMAISVLLAVDPVGDELVAKIQERMANLVTGDGRKGADMGPLITREHRDKVAGYLEVAATDGASVVVDGRGVEADGAADGFWLGPSLVDHVATTSTVYTDEIFGPVLSIVRVASYAEGLELINSGQFGNGTAIFTNDGGAARRFQQDVEVGMIGINVPIPVPVAYHSFGGWKASLFGDSKAYGPAGMDFFTREKAVTSRWLDPSHGGLNLGFPQNE
>NZ_CP040695.2|WP_138876902.1|4232188_4233550_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme
MTATQHPTTAPGEGADLDARTKSLDRNHVFHSWSAQGALDPMVVAGGLGCHVWDHAGNRYLDFSSQLVNVNIGHQHPKVVAAIQAQAAQLATIAPATANLTRGEAARRIIERAPAGLDKVFFTNGGADANENAIRMARLHTGRDKVVSTYRSYHGNTGAAVVATGDWRRVPNEYARGHVHVFGPYLYRSEFWATTPEEESERALRHLRRVVESEGASSVAAVLLETIPGTAGIMVPPPGYLAGVRALCDQHGIVMILDEVMAGFGRAGEWFALDAFSELDGHGPDLITFAKGVNSGYVPVGGVLISDAIAADFDETVFPGGLTYSGHPLAAASIIGALDAMEEEGIVANARRIGAEAIGPGLAELAEKHPVVGEVRGLGVFWAVELVADRDTRAPVPPALIGLAKKECMARGLLPFAADNRLHVVPPCVVTDDQVAEAMAVYDDVLTILDREI
>NZ_CP040695.2|WP_138876903.1|4233680_4234835_-|ABC-transporter-substrate-binding-protein
MLKTMRRNLAVAATLVTASAMLTACGGDDGDDGGGGGGGGGGGTTEVTLQLQWLPQAQFAGYYAAVEQGFFADEGLDVTIEPSGGDIVPQDALAAGDADYAIAWVPKVLGSIEQGANLTNVAQIFQRSGTLQVSMADSGIESVADFEGKRIGSWGFGNEWEIFAAMAAEGLDSESVEIVTQDFNMNAFLQGDIDAAQAMTYNEYAQLLETPNPDTGELYTADDFNVISYEDTEGAMLQDAIWADTERLESDDEYADTTVKFLKAVIKGWAYARDNVESAAETTIAAGSSWGPTHELWMANETNKLIWPADAGIGVIDQAAWDQTVEGALAAVNEQGQNLITAEPPATAYDNTYVEQAIEELGDEVDTTGADYSPIEVTPTEGGS
>NZ_CP040695.2|WP_148240912.1|4234900_4235689_-|ABC-transporter-permease-subunit
MTSPTTPVAHVARVVAPLVVGALIVGLWQFLVSVVEVSPYLLPGPQEIWGELRDNSEAVREAFWITGRNALIGLVFGTVVGIVLAGLAAWARVVDGMLAFAVAALAVVPIVALAPVLNSMYGADSEYGRRAIAAIAAFVPVYVNTVRGLRQTTPQHRDLMHSYSASGWQTFRSLTLPSAAPFVITGIRVASSLAVISALVAEYFGGPRGGLGSFISTSAATSAYARAWAYVVAAIVLGLVAYVATVLLERLVQWRLPTGGAR
>NZ_CP040695.2|WP_137295185.1|4235685_4236609_-|ABC-transporter-ATP-binding-protein
MNTPDPQPAPTLAKDGGEDPAARTPAATSGPTGASTAAPFGTVDAVRVAGVTKTFGTRKNQVTALSEVDLTVRAGEFIALIGPSGCGKSTLMRVVADLEQPTGGTVEVFGKTATQARKDQDYGIAFQQAGLLPWRSVAGNIALPLELHGASRSERKQRVAELVEMVGLTDFAKSRPDQLSGGMQQRVAIARSLAERPRLLLMDEPFGALDEMTRERMQAELARISVETGAAVVFVTHSIPEAVFLADRVVVMSARPGRITEEVVTGIGRDVVRDQRLREDPAFFTKVTEVREALHGAPVASSGAEER
>NZ_CP040695.2|WP_137295184.1|4236605_4237544_-|ABC-transporter-permease-subunit
MSSTAQTSAAPGLVSARPRLVTGAWPVLRSALLGVLGLVAAAGVWEAYKALAPEDGVLVGENRVLPRTTDLSMPHVWDMFQRLGEPVTSMPGAEPLWQVVGDAVVVSLKVAAAGWVVGTVVGLLLALLMSSLRVVEWGLLPWIVLSQTVPLIAFAPMVRSWGSRIEIGGWEWEPWMSVALIASYLAFFPVAVGALRGLQASDRIHTELMHTYDAGWWATLRRVRAPAAVPYLLPALRLGAAGAVVGTVVAEVSIVYPDGIGRMLVQFAGQASGDPEKAWAPIFGAVVLGLVAAGFVALLGLLLRNYRRGEAS

Crispr_ID: NZ_CP040695_17

• CRISPR_ID: NZ_CP040695_17
• CRISPR_location: 4350462-4350608
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP040695_17

Consensus_repeat	Method
GGGGTTTCGTCGGCGCTCGCTGGCGCTCGCTTGCTCAACCTCCGGGG	CRISPRCasFinder

spacers of NZ_CP040695_17

>17.1|4350509|53|NZ_CP040695|CRISPRCasFinder
ACCGGGACGACCGAGGGACCGGGGCGTCCGGGGGCCGGGACGCAGGAACCCCG

CRISPR arrays and Neighbor proteins around NZ_CP040695_17

CRISPR arrays

The CRISPR arrays of NZ_CP040695_17

>merge|NZ_CP040695|17|4350462-4350608|CRISPRCasFinder
GGGGTTTCGTCGGCGCTCGCTGGCGCTCGCTTGCTCAACCTCCGGGGACCGGGACGACCGAGGGACCGGGGCGTCCGGGGGCCGGGACGCAGGAACCCCGGGGGTTTCGTCGGCGCTCGCTGGCGCTCGCTTGCTCAACCTCCGGGG

>NZ_CP040695|17|17|4350462-4350608|CRISPRCasFinder
GGGGTTTCGTCGGCGCTCGCTGGCGCTCGCTTGCTCAACCTCCGGGG	ACCGGGACGACCGAGGGACCGGGGCGTCCGGGGGCCGGGACGCAGGAACCCCG
GGGGTTTCGTCGGCGCTCGCTGGCGCTCGCTTGCTCAACCTCCGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138876962.1|4343671_4344718_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137294750.1|4340260_4341040_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP040695.2|WP_137295685.1|4366022_4367165_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP040695.2|WP_148241032.1|4368506_4369541_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224093
NZ_CP040695.2|WP_137295702.1|4375086_4375947_-|hydrolase-TatD	unknown	unknown	gnl|CDD|224024
NZ_CP040695.2|WP_137294757.1|4349085_4350321_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP040695.2|WP_137295705.1|4372484_4373846_-|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|366747
NZ_CP040695.2|WP_138876968.1|4350736_4357357_-|DUF1349-domain-containing-protein	unknown	unknown	gnl|CDD|377643
NZ_CP040695.2|WP_148240928.1|4375946_4376579_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876961.1|4341476_4343603_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_134768264.1|4341125_4341446_+|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|224278
NZ_CP040695.2|WP_138876974.1|4373875_4375090_-|metabolite-traffic-protein-EboE	unknown	unknown	gnl|CDD|224007
NZ_CP040695.2|WP_138876967.1|4347521_4348919_-|xylulokinase	unknown	unknown	gnl|CDD|273550
NZ_CP040695.2|WP_148240927.1|4346276_4347437_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP040695.2|WP_138876964.1|4345209_4345530_-|AzlD-domain-containing-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_137295372.1|4367309_4368395_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380534
NZ_CP040695.2|WP_148241031.1|4357463_4358519_-|PKD-domain-containing-protein	unknown	unknown	gnl|CDD|214510
NZ_CP040695.2|WP_138876963.1|4344714_4345104_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP040695.2|WP_138876973.1|4371397_4372405_-|TIM-barrel-protein	unknown	unknown	gnl|CDD|224007
NZ_CP040695.2|WP_137294762.1|4345526_4346195_-|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl|CDD|224215

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_148241031.1|4357463_4358519_-|PKD-domain-containing-protein	gnl|CDD|214510	smart00089, PKD, Repeats in polycystic kidney disease 1 (PKD1) and other proteins. Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.	4.18116e-08
NZ_CP040695.2|WP_137294750.1|4340260_4341040_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.5609e-42
NZ_CP040695.2|WP_137295685.1|4366022_4367165_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.17434e-61
NZ_CP040695.2|WP_137294757.1|4349085_4350321_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	9.05266e-55
NZ_CP040695.2|WP_137295705.1|4372484_4373846_-|alkaline-phosphatase-family-protein	gnl|CDD|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	4.53539e-57
NZ_CP040695.2|WP_138876968.1|4350736_4357357_-|DUF1349-domain-containing-protein	gnl|CDD|377643	pfam06283, ThuA, Trehalose utilisation. This family consists of several bacterial ThuA like proteins. ThuA appears to be involved in utilisation of trehalose. The thuA and thuB genes form part of the trehalose/sucrose transport operon thuEFGKAB, which is located on the pSymB megaplasmid. The thuA and thuB genes are induced in vitro by trehalose but not by sucrose and the extent of its induction depends on the concentration of trehalose available in the medium.	2.15239e-87
NZ_CP040695.2|WP_138876974.1|4373875_4375090_-|metabolite-traffic-protein-EboE	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.06565e-05
NZ_CP040695.2|WP_134768264.1|4341125_4341446_+|antibiotic-biosynthesis-monooxygenase	gnl|CDD|224278	COG1359, COG1359, Uncharacterized conserved protein [Function unknown].	1.26127e-20
NZ_CP040695.2|WP_138876967.1|4347521_4348919_-|xylulokinase	gnl|CDD|273550	TIGR01312, Xylulose_kinase, D-xylulose kinase. This model describes D-xylulose kinases, a subfamily of the FGGY family of carbohydrate kinases. The member from Klebsiella pneumoniae, designated DalK (see , was annotated erroneously in GenBank as D-arabinitol kinase but is authentic D-xylulose kinase. D-xylulose kinase (XylB) generally is found with xylose isomerase (XylA) and acts in xylose utilization. [Energy metabolism, Sugars].	1.91387e-130
NZ_CP040695.2|WP_148240927.1|4346276_4347437_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	4.35044e-50
NZ_CP040695.2|WP_148241032.1|4368506_4369541_-|ABC-transporter-permease	gnl|CDD|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	2.73475e-81
NZ_CP040695.2|WP_137295372.1|4367309_4368395_-|substrate-binding-domain-containing-protein	gnl|CDD|380534	cd06311, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	6.40162e-69
NZ_CP040695.2|WP_137295702.1|4375086_4375947_-|hydrolase-TatD	gnl|CDD|224024	COG1099, COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only].	3.2476e-84
NZ_CP040695.2|WP_138876963.1|4344714_4345104_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.76805e-19
NZ_CP040695.2|WP_138876973.1|4371397_4372405_-|TIM-barrel-protein	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	2.43457e-31
NZ_CP040695.2|WP_137294762.1|4345526_4346195_-|AzlC-family-ABC-transporter-permease	gnl|CDD|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	9.00646e-27

Protein sequences

>NZ_CP040695.2|WP_137294757.1|4349085_4350321_+|ROK-family-protein
MSTSPHTSGVQALPTTPAPAPLGGGELLGLMLDGRPRTRADLIELTGLARSTVAGRIEGLLSVGLLLPSGQSRSTGGRPPTRFAFNPAARLVLAADFGVTHGRAALTDLTATVIAEEVSDLDIADGPETTLGWLVEATDRLLERTGRTRADLAGVGIGLPGPVEHHTGRPVKPPIMPGWDGFEVATWVGDRLGAPVLVDNDVNMMALGEHSVVYPHVEHLVFVKVATGIGAGIISGRRLHRGAQGSAGDLGHVQSPQGGDALCRCGNHGCLEAIASARAIAQALDADHSPVVDASRAVLDRLALGDREALAAIRRAGRDIGEVLASCVSLLNPSVIVLGGALAGGAPSLLAGVREVIYARSLPLATGELSVVPAQTGEHAGVIGAATMAVQQFLAPQSVDAMLANPVSQAI
>NZ_CP040695.2|WP_138876967.1|4347521_4348919_-|xylulokinase
MTLALGIDTSTQSVKALLVDADDGTVVAQRAVRHPAGTEVDPQAWLAAVDEVLAALPPAQLRDVAAVGVGGQQHGMVALDAEDRPVRDALLWNDTRSAGAAADLVAEMGGPQACADAIGSVLVASFTVTKLRWLRDHEPERAARVARVLLPHDLVARHLSAPGTDPFTDRGDASGTGYFATAEGRWRPDLAAAALGHEPDLPRLVAPGGVAAHTPDGAVVSAGTGDNMAAALGMALGPDDVLVSLGTSGVASAVSARPVADGTGVVTGFADAAGGFLPMVTTMNAAGILDLQAQWLGVDHDGLADLALESTPDAGGVVLSPYYGGERSPYRPTATGTWTGLTPRTTRADLARAAYTALLCSLADAVDQVVAATGVEPRRVLLVGGAARSRAVRALAPAVLGRPVTVVPPGEYVALGAARQAAWALAGSDAPPTWAGPEAEVLEAEPDPQVRATYADLRERTASWT
>NZ_CP040695.2|WP_148240927.1|4346276_4347437_-|ROK-family-protein
MTTGTEQLRRRHTALVVRTLRRLGPTSRAELAVATGLSKPTIGVIVAGLEADGTVGLDPTGDGRTGEDRVPVRGRPGRPVALRPGRHLGLGLDLNVDYVTAVVLDLAGEVVLSESRPVATDRVEALLATTRELRDRYGADRFVGVTAAVPALVHGDDRTVAWAPNLTLSGPELADALAGVLPDSDVRVVNDANCAAYAEVHHGVARGVDHALYVTGTVGIGVGIVAGGVLVQGATGFAGEAGHVAVGDPTALCGCGRRGCWEASVGLHAVLRSLGMEELGTPTATGEAVAARAAHDAAAQEVLARVGRDLGLGLATLTSVLDPEVVVLGGYFVPLGDLVLDHARAALDARLDPPTRRRPELRLSTLGLGAAALGAAEQALAGVLLG
>NZ_CP040695.2|WP_137294762.1|4345526_4346195_-|AzlC-family-ABC-transporter-permease
MPYGAVALVLALSFSVLAVNAGFTPLQAVVTSALVFAGSAQFTALTIVAGGGSIPAALSAAALMHSRFLAMGVALAPSLTGGRLRRAVEGQAVVDSSWALANRGDGTFDRGLLFGTTLPQYVAWTTGAVVGAFSGDVLADTERLGLDALFPTFFVAILLAELRQPRARVVAALGAGIAIALVPLAPPGVPVLAAGAAALLGLGAARPGPVDGAGDDAARGDG
>NZ_CP040695.2|WP_138876964.1|4345209_4345530_-|AzlD-domain-containing-protein
MNLSEAQVWLLIAGLVGVAVVTKGIGPAVVGDRPLPGWSAGVIAALAPALLAALVATALLADGRRLAVGAEAVGVAVATVLLLCRAPLLAAAAAAVLVTALLRALV
>NZ_CP040695.2|WP_138876963.1|4344714_4345104_-|PadR-family-transcriptional-regulator
MDTTQLLKGVLDLAVLAVVEEEDGYGYDVLRRLRASGLSEVGDASVYGTLRRLYAAGALTSYVVPSDEGPHRKYYGMTPAGRDQLERQSKDWATFSETVTELLHPDRRPGPRSEPRLDPHPARPEGDHP
>NZ_CP040695.2|WP_138876962.1|4343671_4344718_-|hypothetical-protein
MTTRAPHRTTPDIASFVSQVRAHLSDLSEEEREELVGGLEADLVDHLADPTNRTDLGDPAAYAAELRLAAGLPEHAGRRARLRVPRPPGVEDLLDQSRARFDRVVEERAWSRATWDVVRELRPVWWVARAWIAVTLLDLVAGDHEPLSLVPSLGHPATGAVLLAAAVVVSVLVGLGRPGPGPGGHRHPATRLVTLAVNVGLVVTMLSFGVPWPGYLAGNAVEAQPYDGYRPGFNDGARSERRPGLQLDDEAVTNVFAYDAQGLPLQDVQLFDQDGDPLAVASGTSTGRGAERRVPCPALDADTELLNVFPLDEVQLRTGRCTAETTGRSTPLPPLARARPVPVAPVVP
>NZ_CP040695.2|WP_138876961.1|4341476_4343603_-|hypothetical-protein
MPRSLPQVPGLTVARFEGWYAGADLPEGPPPRVAGRVLGELFARAQRGGGDLHDPTAELLRWLLRDVVRDGIDPGDDYDLVLMTLVRYLLFLRRTERWRRSERAVQDCWDVTTWGTQPPLGLGSLGPTVDESFATGLAAVPSAHDVLGAGAARPFLGFLRATLDVLGTGPSLPRSAAARLVGLADGTVALRLWVDALHETGLVRVDGGGQVLEARGEVRDAGGCPPPSADLVDLVVMGLVRAAVDSAFDAALRSDDQRRPLAAAAALAVALVAGCDESYLLAEDEDDEEESTASVVTQMAEAMLGDDAAGLAPVTAEVMRTLDALASLGLLDDVVLERGSHVLLVPEALRHRVIRTLSDHLGVVGTDDTAVVWAPVDLPSTLPEGAGVELTAALGGVDVVRLRVGAATSLGDLHRVVSFALRRPVARRHVYCHVDGVRRFTGTSWLRSFEERDDAEVTDDGAAAVGAVLAEPGAELDLVLDGTPVPVRLRVGAVLATAPATAVVVGPDGAEEPLAARHAVLDARLPPGSGLARHLLVLAATGRHDHAGLVGVALDLVTADDFGRRFPGERRPTQGEAVALVEEVVAEHRRLVPRASPGAQALLRALTTLPGRGVAVFLAGHTWTPASSPLGHVATTAREEARAILTDEVTLTYGGADRSDDAAAERVGRILAEALTEAGLDVDWDGDPRWPVVVTPLRWEWPFGVPLD
>NZ_CP040695.2|WP_134768264.1|4341125_4341446_+|antibiotic-biosynthesis-monooxygenase
MILICVKWKIKPEHADSWPELAREFTEATRAEPGNRFFDWSRSVEDPTEYVLLEAFDDDAAGPHVQSDHFKKAQADLPQYVVETPQIRNWQNEPDEWHRLGEFEVS
>NZ_CP040695.2|WP_137294750.1|4340260_4341040_-|IclR-family-transcriptional-regulator
MSVMSATAGEQRPGSVARTFDILEAVAARGGASAKEIADVTGLPLPTVYRLVRELLDGDYLVHIREEKRFELGYKLHALGVSLHEQIGVSRQVRAEVTALHQQLGTAAYLAVHRGSQIVVVLTVDSPAHPRLPPIDFGFHEAAHATAFGKILLARMDDEERAALLDPEPMPRFGPGTITTHAELHAQLDTVAERGIAWEFGEFQAGSTCAAAAVRGVAGALVGSVAISAPDPVLAHGRADVEQVLRACASRIGRFYRSA
>NZ_CP040695.2|WP_138876968.1|4350736_4357357_-|DUF1349-domain-containing-protein
MAALAVTGGVMAAAPASAAPAAAAPAISSSSLSSAQAAPTTSGAAAPAASAAPAAAAAPAAAAAAAAEPEYDVLVFSKTAGFRHGSIGAGIRSIQRLGAQYGFTVTATEDATTFTTANLAQYEAVVWLSTTSDVLNATQQAAFEDYIQAGGGYVGVHAASDTEYSWPWYGKLVGAYFRNHPNGTPTATVRFEDKTTPSTCAMPDSVSRTDEWYNFQPTEGTFAGGPLPFPGGNGPATVPDYSPRSNSNINVLATVDESTYDEVDGNTTDDDHPIAWYQEYDGGRSFYTGGGHTDASFSEPLFELHLLGGIQYAADQAPTACTELPPTDASFEQVTLAKGVDKVGEPMSISVLPDGRVLHNARDGRIFLTDLEGNTTLLYDVPIYSHDEDGLQSLTVSPNFEEDGWVYLYYAPPLDTPAGDAPNDGTEATFQAWKGHNVLTRMKMVDDDLVPSTEQELLQVEADRGICCHAGGAIDFDADGNLYLSTGDDSNPFASDGYAPLDERLTRNPSYDAQRSSANTNDLRGKVLRIKPDATAATYTVPGGNLFPEAADTGDKTRPEIYAMGFRNPFRMTVDKETGYVYLGEYGPDAGSANPNRGPGGIVEFNQIRSAGNFGWPYCTGLNTAAETYNRWNFATNATGPKFNCAAPVNNSPHNTGLTNLPPAQPAWIKYDGGSVTYNGVTTDEFGSGGEGPMAGPVYNYDPDLDSDVKFPEYFDNHFFAGEWTRGWIRDIALDAEGDVSSIDPFFDSSTLYAAMDMEFGPDGSLYVLDYGNGGYFTGNENSAVYKINAINEGARSPSASARATPDSGVAPLPVQFSSEGSSDPDEGDSIASYAWDFQNDGTVDSTEANPTFTYTTNGVYDARLVVTDTTGRTGVATAVVTVGNTRPTVELELPPNGGFFEFGDAVRVKVNVTDPEDGVIDCSKVEIDYILGHDSHGHPLSSATGCDVVLQTVKDEGHDASADIFGVINASYTDEGAGTIRTLSGEDEVVLQPKRKQAEHFDTQQGVATEATTDPQGGARNVSNIDAGDHVSYGPISLFQVPQLRFRVASGGAGGTIEAHLDSPTGPLAGSVDVPVTGGWQSWQTVAMDVAASAQEGTHELFLVFTNDNPAATGLFNLNFFDAAGKGVSINSKPQVGATGTPTQGSSPLTVDFTGSATDFDGDALTYAWDFGVPGDADTATTLNAQWTYTEPGSYTARLTVTDAQGATASSTVPIRVLSTCGTQQSDEFDGTSLDGKWQVIRPSGNIAVTGGSLTMPIDTGSLYGPGGNAKDVVVQAAPDGAWEVTAKVTADVSENYQQAGLRLYSDDENWASVHLISAGGARDVEFIYETQGSARNNAEDKLGGVPAGFPTTYYVRLTSDGTDLRASYSTDGETFAPVGRPAPMGTMPSPKVGPTAVSGGAVGTPTVAFDWIRFDPDGTSGAAGPRDDFDGTSLDECRWNAIVREDPDAYEVAGGALTIQGAPADLYTASANQDQATNLILQSDANTTEDYSIETQLSATYTDGYGQAGLLIYGDDDNYVKLDPVADVDRPTESFNRIELRSESNAAILNPQPEVVVPPNVSTFKLRITKTGTSYLGEVDFGGGWVTVGTVSNPTADMDFGVFSLGVQQSGQSGTFDYFEVTGAGTENRAPVADDDTATTEQGIALDVPVLVGDTDPDGDDLTVTAVTDPANGTTAINADGTVRYTPGAGFTGTDTFGYTVSDGELTDTATVTVTVTEPCGPTSSDDTFEGTALDKCRWDAIQAEDTTKYTVVDGELRLTTTPGEIYLAGTAKSNYILQSASHAGDDFVLETGLDASALTGGYSQAGIMVYGDDANYVKLDFLTGENAGSAIKVEMRSEVGDVIVGNLPETTLAAGQGADLRLRLTKAGSTYSGEFSVDGGTTWTALASTVSNEMTKPSFGVFAAGVQDSGDVVSFDYFTVDGEDPLNAAPVAADDNATTVQDTAVSVDVLANDTDADTGATLTVESVTTPAHGTATIAGDGSVTYTPAAGYTGSDTFDYVVSDGTDTDTGTVTITVTAAPAGVTDTRITSAPSGTTRSRTATLRFTATGPAAGQATFECSIDGSAYAACTSPKTFGNLKDGRHTVRVRSVSAGGVDASPATATWTVDATGPKVVGTSPKGTTRDRTPTIKAKVTDGTSGVRAGSLKVFIDGKRVSPVRYVKATGRLTATPKRALGFGRHTVRVVAVDTAGNQTATTWRFTVRR
>NZ_CP040695.2|WP_148241031.1|4357463_4358519_-|PKD-domain-containing-protein
MVRSRGETYTTLDVTGVKPNANHMVHVHEETCASNNGGAHFRFDETQPFAEANEIWLPFTADATGASTLVEDTMPIRAGAKAVSIVIHDPDNGAKRIGCVDLAPSTADLTYDWDFGDGTTGTGADPDHTYAEPGTYTATVTVGSVHAGHMPGHDATTTAEVEIVVEDGETPDTTAPQTTVTAGPTGTVRSTTATFRLASDESGTFECRLNGGAWRPCASPATFTNLRQGAQRLEVRAVDAAGNEDATPVVRTWKVDTQGPVVKNLGPRGTTRDRTPTVRAVVRDQGSELARRHLTLRIDGKKVGVRYDARTDRMTWTSGRAMSIGRHTVRLVVVDAVGNRTTKTWRFTVRR
>NZ_CP040695.2|WP_137295685.1|4366022_4367165_-|Gfo/Idh/MocA-family-oxidoreductase
MVGHAFMGAAHSQAWRSAGRFFDLPLNPVMQVLGGRDMARTAAAAEKLGWLDCETDWRRLVERDDVDLVDICTPGDTHAEIAIAALEAGKHVLCEKPLANSVAEAEEMVRAAEAAAAHGVRAMVGFTYRRVPAIALARRMVAEGRLGDIRHVRAQYLQDWIADPEAPLSWRLERDKAGSGALGDIGAHIIDLAQHITGDHIAEVSGQLETFVKERPLAAEHAGLSGTASAERGQVTVDDAALFLARFRGGAAGIFEATRFATGRKNAIRLELNGSRGSLAFDFEDMNVLEYFDAEEPDETAGFRRILVTEPTHPYVAAWWPPGHGLGYEHGFTHQAVDLVTAIAEGTDPTPGFAEGLQVQRVLGAVEVSSDTRQWQQVPA
>NZ_CP040695.2|WP_137295372.1|4367309_4368395_-|substrate-binding-domain-containing-protein
MSLKFLSAPRAGAYKSAKFTATLAVVAVLGLSACTSNDSSEEEGNPNLSGGNSGAEEGSNDEAGDKITIGFSAPAADHGWMASITESTRAVAEQYDDVELVVSEGTNDPNVQIEQIKTFISDGVDAIVLLPFDGAALTPVALEAMEAGIPVVNVDREFSDPNAARVTVLGDNYGMGVSAGEFVCEDAAGNEDAVIGEIQGIASLPLTQDRSQGFADALAECGLEVENQVEAAFSADTGQEAAEGLLQALPKMDYLWNHDDDQGVGVIAAIEAAGRDEFTMIGGAGSQQAMESIKAGNSVLKATVIYPSTQGADGLKLARLLAQDKNVSDLVEVEVPRTVQLFAPVVTADNVDEYLPTAFKS
>NZ_CP040695.2|WP_148241032.1|4368506_4369541_-|ABC-transporter-permease
MTASGPGGAGGGGGAAGGSTMARLADMGFFRIIGLVVVLLLIAVVGTITAGDRFLAADNFQSILRQGTVVGIVAIGMTFVITGGGIDLSVGAVVALSSVWATTLATQEMAADTHWLLLVLAAIAVGAGAGLVNGILIAYGKIVAFIATLAMLVAARGLAEIISEKRTQIVSSSDLPGFYDFFNAKPLGIDMQIWLFAVVAVGVGVLLNRTTFGRRTFAVGGNPEAARLAGINVRRHTVLLYVLVGVCAGLAALILIAKTTTGSANHAELLELDAIAAVVIGGTLLAGGRGTITGTVLGVLIFNTLTNVFTLNNRPPSEQDVLKGAIIVAAVLLQQWLASRKSTT
>NZ_CP040695.2|WP_138876973.1|4371397_4372405_-|TIM-barrel-protein
MPRPITLFTGQWADLPFEEVARLASGWGYDGLEIACWGDHLDPWQAAEDDAYVQGKLDLLEKYGLKVHAISNHLKGQAVCDDPIDGRHEAILSSRVWGDGDPEGVRQRAAEEMKLTARTAQRLGVDTVVGFTGSAIWKYVAMFPPATEEMVAAGYRDFADRWNPILDVFDECGVRFAHEVHPSEIAYDYWTTVATLEAIGHRPAFGLNWDPSHFVWQDLDPVGFLWDFRDRIYHVDCKDAKRQVGNGRNGRLGSHLPWADPRRGWDFVSTGHGDVPWEACFRMLNTIGYQGPISVEWEDAGMDRLVGAPEALEFVRRLAFDPPSAAFDAAFSTSS
>NZ_CP040695.2|WP_137295705.1|4372484_4373846_-|alkaline-phosphatase-family-protein
MLVVDVVGLTPDLLRHMPRAQRVATAGFAAELGTVLPAVTCSVQSTFLTGLLPRDHGIVGNGWYFRDLGEVLLWRQHNALVQGEKLWDVIRRERPGYKVANVCWWYAMGADVDSTVTPRPVYHADGRKSPDCWTWPPELHDRLTDKLGPFPLFTYWGPTAAIPSSRWIVEAARELMPEHDLTLVYVPHLDYDLQRFGPDSEQAVQAARDVDEVLTPLLDDAERTGTTVVLLSEYGITKASRPVDVNRLLRREGLLHVHHNATGELLDPWTSRAFAVADHQVAHVYVKDPADLPRVRALCEGLDGVDQVLDREGQAELGLDHERAGELVLVAEPDAWFTYYYWLDDALAPDFAKAVEIHKKPGYDPAELFLDPEDRLVKARAGLTLVRKKVGLRYSMSVVPLDPAPVSGSHGRLPSRPEDGPVLLCSDPSVKAERIEATDVRDLLARLATGSRP
>NZ_CP040695.2|WP_138876974.1|4373875_4375090_-|metabolite-traffic-protein-EboE
MRFRHRDGSLVHLSYGSNVHPAETVDGIVAQLRTYAAGVRSALDADVLGVGLWLPAAVAHELARDAGARDRVRQVLRAERLEVVTVNAFPYRGFHDDVVKKAVYLPDWTDDARLDFTLDCARVLADLLPDEAVRGSVSTLPLGWRTPWDDDHDRAATDVLHRLSDGLAALADDVGRPVRVGLEPEPGCLVETAADAVERLAWLADLGPGLVGVCVDTCHLAVGFEEVADALDDLESAGLPVVKVQASAALHAARPGDDETRAALAGWAEGRFLHQTREPVGAEVSGRDDLDEALGLDGAGGEPLPARRPWRVHVHVPVHADPEPPLRSTRPHLEAGLTALLGGDHPVVDHVEVETYTWGVLPPELRPRDDAGLVAGIAAELAWARDRLVALGLDPVPGLQGAPS
>NZ_CP040695.2|WP_137295702.1|4375086_4375947_-|hydrolase-TatD
MRIFDPHIHMTSRTTDDYEAMHAAGVRAVVEPAFWLGQPRTGVDSFIDYFDALLGWERFRAAQFGIAHHCTIALNPKEANDPRCTPVIDLLPRYLAKDGVVAVGEVGFDSMTEAEETAFTRQLELAGEHGLPAMVHTPHRDKLAGTHRTLELVAAVGLPAGHVLVDHLNEVTVDVVDDAGAWMGFSIYPDTKMDPHRMVAILERRGLDRVLVNSAADWGRSDPLTTRQTGDAMLAAGFSDDDVDRVLWRNPVEFYGQSGRLLLEAPQVEATDTFEGSSVLRGERAS
>NZ_CP040695.2|WP_148240928.1|4375946_4376579_-|hypothetical-protein
MTTLDEQTEQRLAAAEDAVRADPARVRSLFPAAGRDIGRTPTAPGAAPGEVRVEDVVRVRLLGALGEALAADPDALAQEVADLYRFGDAAERRAVLLGLATLVSAGRPERAALLVHDALRTNDVRLVAAALGPAGAALLDADAFRQAVLKCLFVGVPLDLVAGLDERADATLRTMVASYADERRAAGRAVPDDALTLLDPAGPDAPTQES

Crispr_ID: NZ_CP040695_18

• CRISPR_ID: NZ_CP040695_18
• CRISPR_location: 4391468-4391559
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP040695_18

Consensus_repeat	Method
GGGAGTTTCACCGCCTCAGCGGTGAAACTC	CRISPRCasFinder

spacers of NZ_CP040695_18

>18.1|4391498|32|NZ_CP040695|CRISPRCasFinder
ACGCTTCCTGCATGAAGCTTCACGACAGGAGC

CRISPR arrays and Neighbor proteins around NZ_CP040695_18

CRISPR arrays

The CRISPR arrays of NZ_CP040695_18

>merge|NZ_CP040695|18|4391468-4391559|CRISPRCasFinder
GGGAGTTTCACCGCCTCAGCGGTGAAACTCACGCTTCCTGCATGAAGCTTCACGACAGGAGCGGGAGTTTCACCGCCCCAGCGGTGAAACTC

>NZ_CP040695|18|18|4391468-4391559|CRISPRCasFinder
GGGAGTTTCACCGCCTCAGCGGTGAAACTC	ACGCTTCCTGCATGAAGCTTCACGACAGGAGC
GGGAGTTTCACCGCCCCAGCGGTGAAACTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040695.2|WP_138876986.1|4389937_4391365_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240541
NZ_CP040695.2|WP_138876988.1|4393653_4395894_-|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_CP040695.2|WP_138876979.1|4382725_4382938_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP040695.2|WP_138876981.1|4384610_4384967_+|hypothetical-protein	unknown	unknown	gnl|CDD|377688
NZ_CP040695.2|WP_138876984.1|4386466_4387618_+|ACR3-family-arsenite-efflux-transporter	unknown	unknown	gnl|CDD|213563
NZ_CP040695.2|WP_134768758.1|4392130_4392367_-|30S-ribosomal-protein-S18	unknown	unknown	gnl|CDD|178997
NZ_CP040695.2|WP_148240932.1|4399034_4400471_-|hypothetical-protein	unknown	unknown	gnl|CDD|227937
NZ_CP040695.2|WP_137295672.1|4386092_4386470_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP040695.2|WP_134768760.1|4393174_4393480_-|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|179034
NZ_CP040695.2|WP_137294600.1|4397979_4399074_+|alanine-racemase	unknown	unknown	gnl|CDD|376473
NZ_CP040695.2|WP_137294601.1|4396787_4397975_+|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	unknown	unknown	gnl|CDD|225224
NZ_CP040695.2|WP_137294598.1|4400467_4402780_-|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP040695.2|WP_138876985.1|4387614_4388028_+|arsenate-reductase-ArsC	unknown	unknown	gnl|CDD|319973
NZ_CP040695.2|WP_137295675.1|4388080_4389499_-|replicative-DNA-helicase	unknown	unknown	gnl|CDD|273206
NZ_CP040695.2|WP_148240931.1|4385535_4386012_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP040695.2|WP_138876982.1|4385010_4385487_+|polyketide-cyclase	unknown	unknown	gnl|CDD|176867
NZ_CP040695.2|WP_138876987.1|4392432_4393035_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|236092
NZ_CP040695.2|WP_137294605.1|4391656_4392103_-|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NZ_CP040695.2|WP_138876989.1|4395892_4396687_+|deoxyribonuclease-IV	unknown	unknown	gnl|CDD|179214
NZ_CP040695.2|WP_148240930.1|4383012_4384614_+|MFS-transporter	unknown	unknown	gnl|CDD|340863

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP040695.2|WP_137295672.1|4386092_4386470_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	1.9e-20	68.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040695.2|WP_138876986.1|4389937_4391365_+|MATE-family-efflux-transporter	gnl|CDD|240541	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.45049e-94
NZ_CP040695.2|WP_138876988.1|4393653_4395894_-|FHA-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	3.32544e-23
NZ_CP040695.2|WP_138876981.1|4384610_4384967_+|hypothetical-protein	gnl|CDD|377688	pfam06689, zf-C4_ClpX, ClpX C4-type zinc finger. The ClpX heat shock protein of Escherichia coli is a member of the universally conserved Hsp100 family of proteins, and possesses a putative zinc finger motif of the C4 type. This presumed zinc binding domain is found at the N-terminus of the ClpX protein. ClpX is an ATPase which functions both as a substrate specificity component of the ClpXP protease and as a molecular chaperone. The molecular function of this domain is now known.	4.17248e-15
NZ_CP040695.2|WP_138876985.1|4387614_4388028_+|arsenate-reductase-ArsC	gnl|CDD|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	6.47981e-47
NZ_CP040695.2|WP_148240932.1|4399034_4400471_-|hypothetical-protein	gnl|CDD|227937	COG5650, COG5650, Predicted integral membrane protein [Function unknown].	5.05804e-17
NZ_CP040695.2|WP_137295672.1|4386092_4386470_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	9.12623e-19
NZ_CP040695.2|WP_134768760.1|4393174_4393480_-|30S-ribosomal-protein-S6	gnl|CDD|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	3.57204e-40
NZ_CP040695.2|WP_137294600.1|4397979_4399074_+|alanine-racemase	gnl|CDD|376473	pfam01168, Ala_racemase_N, Alanine racemase, N-terminal domain.	2.63347e-14
NZ_CP040695.2|WP_137294601.1|4396787_4397975_+|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	gnl|CDD|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.39184e-37
NZ_CP040695.2|WP_137294598.1|4400467_4402780_-|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	2.55262e-150
NZ_CP040695.2|WP_134768758.1|4392130_4392367_-|30S-ribosomal-protein-S18	gnl|CDD|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	1.69923e-36
NZ_CP040695.2|WP_137295675.1|4388080_4389499_-|replicative-DNA-helicase	gnl|CDD|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP040695.2|WP_138876989.1|4395892_4396687_+|deoxyribonuclease-IV	gnl|CDD|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	3.96835e-103
NZ_CP040695.2|WP_148240931.1|4385535_4386012_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.14221e-42
NZ_CP040695.2|WP_138876982.1|4385010_4385487_+|polyketide-cyclase	gnl|CDD|176867	cd07825, SRPBCC_7, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	5.57998e-48
NZ_CP040695.2|WP_138876987.1|4392432_4393035_-|single-stranded-DNA-binding-protein	gnl|CDD|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	1.04475e-83
NZ_CP040695.2|WP_137294605.1|4391656_4392103_-|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	5.32629e-60
NZ_CP040695.2|WP_138876984.1|4386466_4387618_+|ACR3-family-arsenite-efflux-transporter	gnl|CDD|213563	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein. The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. [Cellular processes, Detoxification, Transport and binding proteins, Anions].	1.61119e-146
NZ_CP040695.2|WP_148240930.1|4383012_4384614_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.50594e-48

Protein sequences

>NZ_CP040695.2|WP_138876986.1|4389937_4391365_+|MATE-family-efflux-transporter
MYFRPRRITSVVAVRRRPDPSDTPTRTPTSADGRSQDREILRLAVPAFLALVAEPMFLLADAAVVGHLGTPELAGLGIAAVVLQTAVGLCVFLAYGTTAGVARRMGAGDLRGALSLGLDGVWLATGLGAVITVGGVLLTDPLVAAFGVGGEVAGHATTYLRIAFLGTTPLLVMLAATGVLRGLQDTRTPLVVAVVGNLLNVVLNVALVYGLDLGIAGSAIGSVVAQVACAVALTAVVVRGARRHDAPLRPDLAGVRAAARAGVALVVRTLTLRAALLVTTVAVTLDARGDDGADRIATHQLAMTLWTFLAFVLDAIAIAAQAITGRALGAGDVDTARALTRRMVRWGLWSGVVTGIAIAALSPVLGPLFTDDPAVPDLLVPVLLVAAIGQPAAGVVFVLDGVLIGAGDGRYLAWAGLLVAALYAPVTLAAAVWWDAGLLAVWVLFCGLFMGGRLVTLLHRARGDAWLRTGATVDA
>NZ_CP040695.2|WP_137295675.1|4388080_4389499_-|replicative-DNA-helicase
MSLTESDSRGFPEPPYDDWGDGPAAYEPGNAPSSPGGRTPPQDMAAEQSVLGSMLISKDAIAEVSEVLRGNDYYRPSHEIIHDAIIDLFGRGEPVDMITVAAELQRAGELAKIGGAPYLHTLAANVPIAANAEFYAQIVHEKSVLRRLVDAGTRIAQFGYAGEGQVDDIVDRAQAEIYQIADKRSTEDYAPLSDIMEGVLDEIEAISNRENGLYGVPTGFADLDDLTNGLHAGQMIIVAARPAMGKSTLALDLCRSASINNNLASVFFSLEMTRSEITMRLLSAEAKVPLNHIRNGNMQDGDWDKLARHMAKVSAAPMFIDDSPNMTMMEIRSKARRLKQRHDLRLIVIDYLQLMSSGKKVESRQLEVSEFSRQIKLLAKELGVPIIALSQLNRGPEQRGDKRPMMSDLRESGSIEQDADMVILLHRDDVYEKESTRPGEADLLVVKHRNGATRDITVAFQGHYSRFVDMAH
>NZ_CP040695.2|WP_138876985.1|4387614_4388028_+|arsenate-reductase-ArsC
MTTPEVLFVCVHNQGRSQMAAALLARHAAGRVRVRSAGSAPADSVNPAVVEVMAEIGIDISQELPKKLLTHDVAAADVVVTMGCGDACPIYPGKRYEDWVLTDPSGKGPDSVREIRDEIDQRVRALLAELVPDTPTA
>NZ_CP040695.2|WP_138876984.1|4386466_4387618_+|ACR3-family-arsenite-efflux-transporter
MSDVVGERAGTSSEDAVATRLSTLDRFLPVWIVAAMALGLLLGRSIPGLDDALASVEIGSVSLPIAVGLLVMMYPVLAKVRYDELGRVAADRRLLAASILLNWIVGPALMFALAWLMLPDLPEYRTGLIIVGLARCIAMVLIWNDLACGDREAAAILVAINSVFQVVAFAGLGYLYLELLPGWLGLADTGGGGGGGLHVSVWDIATSVLVFLGVPLLAGFLTRTLGERARGRDWYETTFLPRIGPTALHGLLFTIVVLFALQGDTITHRPLDVARIALPLLAYFALMWAGSFALGVALGMTYERTTTLAFTAAGNNFELAIAVAIGVFGVTSGQALAGVVGPLIEVPVLVGLVHVSLWARRRYYPRATTRTRHRPPATGKRST
>NZ_CP040695.2|WP_137295672.1|4386092_4386470_+|helix-turn-helix-transcriptional-regulator
MSNSARPVPVPPDALACCTPLAREPMGEDQAATVAPLLKALADPVRLRLMSLVLSHEGREACVCDLLPAFDLSQPTISHHLKVLHEAGLLDREKRGVWVYYQARPEAMEAMVNLFAAVVPAGTSV
>NZ_CP040695.2|WP_148240931.1|4385535_4386012_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MSRVQLALRVADLEASIAFYSTLFDTTPAKRRPGYANFAIAEPPLKLVLLEGRAGEDTRMDHLGVEVETTDLVTDAHHRLAEAGVLTRPEDNTTCCYAVQDKVWVTGPGREPWEVYTVKSDARPDLEGHAEEPGAAVDGTCCTTNDEAMRLTVSPPGR
>NZ_CP040695.2|WP_138876982.1|4385010_4385487_+|polyketide-cyclase
MTHECISATARVEASAASVFAVLADPSQHRAIDGTGRVRDPVEPVPITAAGQIFRVGMFHERHPDGTYEMANLVLDLVPPHVISWKPGHRSAGTGDLEFGGWTWRYDLSALGPSLTEVTLTYDWSATTREARRVQGFPPFPPTHLADSLTHLAALVTP
>NZ_CP040695.2|WP_138876981.1|4384610_4384967_+|hypothetical-protein
MTPTNPDDHHCSFCGTLGTEAERFIAGPGVYICNECVEVCVDILAGKPTPSFPPLDDKSDDDLLRDMAQIAASRDQVEEAVVDRAQRLRARGVTWARIGEGLGMTRQSAWERFSTDLD
>NZ_CP040695.2|WP_148240930.1|4383012_4384614_+|MFS-transporter
MERRSRTTAPPDAPTGARAAAGQDDGSGQRWEEGLHEPSTPPRPGWLSAHRWGLRRVRRRRYHRPACRVLGGRTASRAGGRRTEGATDDGRAAARGPSVNRPGFRSALASTAFRRLCLAHGLATVGQLVVTLAVGVHVLAETRSGVWVSVTVASAFAPYALCSALAGVLADRRSRSAVLAGAAWVRTALALVLVAGTAAGWPVAVLAGVTALVAVAATPSFPSLAAATPQCVPDRDLPPANALVTCVENVTWIGGPGVFGLLVLAGAGTEVTVLVAAVLFAVAGTVAASVRLRRPARDRATGWWADLVAGVAAVARRPEVRRPMGLAVVDNLLYGYLVVAIVLLADAAPGDDDPLGLLNAALTVGALASMLVVNRCTRGDRTSAVLVVTLVGFCLTLAALGAVGATALGVALLVVAGGTTMVAEVAAVTLLQRSTDTGTLARVFGIYDQLNVGAIALGSLAAGPLSAVAGPHAGLVAVAGLGIVLTLPALLGQLGPARAGAGATRRRGRLASGSVRRSLTTRQDVPDTAEGTP
>NZ_CP040695.2|WP_138876979.1|4382725_4382938_-|hypothetical-protein
MDSLGGLHPVRGVLVRAAGRLTLMRVVGYDVGRGPVRPASYLVTVSGGASDGPGLRAILRHVTPTVFSTP
>NZ_CP040695.2|WP_137294605.1|4391656_4392103_-|50S-ribosomal-protein-L9
MKLILTQEVDGLGSPGDIVEVKDGYGRNYLIPRNVAVRWTRGGQKQVDSIKAARSTRSVRDAAHADELRAKLEASSVDVKVRAGDSGRLFGTVTVADLADALGEAAGETVDKRTIVVTNPIKTLGAHTVAVKLSDDVSATVSLNVIPA
>NZ_CP040695.2|WP_134768758.1|4392130_4392367_-|30S-ribosomal-protein-S18
MAKAVLRKPKKKVCQFCKEKATGVDYKDTTLLRKFISDRGKIRARRVTGNCVQHQRDVAIAVKNARELALLPYTSTGR
>NZ_CP040695.2|WP_138876987.1|4392432_4393035_-|single-stranded-DNA-binding-protein
MAGETLITVVGNLTDDPELRFTPSGAAVANFTVASTPRTLNKQTNEWEDGEAMFLRCSIWRQAAENVAESLQKGARVIVQGRMRARTWETREGEKRTSFEIDVDEIGPSLRWATAKVARAGRSTAGGGGGGYSGGGGGAGGGAGGGGGYSGGGGGGQAEDPWASSAPQSGGRPAAGGGGGGAPANDPWGAPGVGSDEPPF
>NZ_CP040695.2|WP_134768760.1|4393174_4393480_-|30S-ribosomal-protein-S6
MRAYEVMVILDPSLEERTVEPSLDKYLNVIRKDGGTVDKVEVWGRRRLAYPIKNAEGAKNAEGIYAVINLQAEPATVKEFDRQLGLNESILRTKVMRPDAH
>NZ_CP040695.2|WP_138876988.1|4393653_4395894_-|FHA-domain-containing-protein
MRPTLGTATDIAAGVSLAREGSPSIRAAGPVRVARLEPTESAMTSIRIQTSGQTLTADSTEGARVFTVGRDAASDITSLDPTVSRRHAEIRALGQGWEVVDLGSSVGTFVGGRRVERADLTGTTVVGFGRDGQALTVTVTVTPAAPQSFPPPSAPRLDKPAPSAPLGAPAAAPPQAFPPPVAVERLPQFDGPPPLDQTVVTGQGPFPGFGPAGPGLLVRRRTGKDLRFPAGMPIRVGRDPVLEVHADDQAVSRLHAVLEPRPDGWWWVDRSTSGSFIDGERITQHHVDEPVEISLGHPTAGYEIEVVPVVAAGQASARIQARKRRRTLALVGGVVGAMVLVGGGITGVALLGDDDPPAAGQGTTTDPAEERQEALTRAKAAAVLLTAFDESDQPLWSGSGSIITEDGLILTNAHVADPDAPGQTSGESDPAYLTVSLTSGEDDKPASAAFRAAPIVSDGYLDVAVLQIESDAEGNPVEKTELDLPEPLPIGDSDDLRTGDRIIALGYPAIGNLSVQGDRPLTVTEGVVSTFQADEVVGTPRGSIDSDVRLGSGNSGGPSINEEGEIIGLNTRVVTAGSDAAGAITQGSALIVPVNLATAVLDIARDGGDPSYVSPYLDELPTDPGVPTDVAAQAAGWVREGEEGSCAGASSPDAPQKLSGVGTGETLMAEFNVEGLPDGLPLAIDFYDQDDIRIDTLTTTWDLGPEGICIWAPLELSTDFPEITAVLSLGQESEPVAVNPLILSGS
>NZ_CP040695.2|WP_138876989.1|4395892_4396687_+|deoxyribonuclease-IV
MTIAIGAHVDQTDPLAEARARKAPLVQFFLGDPQSYGGPEWAYAGGPEALRADAEAAGVDLYVHAPYLVNVATTNNRIRIPSRKLLQQHVDAAASIGAKGLIVHGGHVNKADDPEKGFDNWRKAIEATDLKLPLLIENTAGGDNAMTRYLERIGRVWEAISGAEGFDMVGFCLDTCHAHAGGNDLETVVDDVRAITGRIDLVHCNDSRDEFDSGADRHANFGAGRIDPDLLAAVVRDAGAPVVCETPGGAAEHTADFAWLSARL
>NZ_CP040695.2|WP_137294601.1|4396787_4397975_+|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein
MTIDVRVTSEADHLAFVASRRSASFLQTPAWGRVKGEWRRESVGLFRDAGPDAEQVGAALVLYRQLPRLRRYLAYLPEGPVLDWASDDLGALLGPLAAHVRKQGAFGIRIGPPAVVRRWDAAAVKAGLADPAVRRLDDVAPTERDATGARVVSQLHALGWRPQAVEGGFAAGQPQYVFQVPLRHPADGSGAGDGVGAAKTEADVLKAMNQLWRRNIKKAAKEGVEVTTPDAATGVSDADLAAFHALYRHTAERDHFTPRPLGYFRTMVDALAAEDPDRIRLWFAHHEGDLVAATIAIRVGAHAWYSYGASSTEKREVRGSNAVQWAMIQDALAAGADVYDLRGITDTLDADDSHAGLIQFKVGTGGEAVEYAGEWDLPLNRVLYAAFQQYLKRRR
>NZ_CP040695.2|WP_137294600.1|4397979_4399074_+|alanine-racemase
MALTLTVDGDRWRSHLRGVADANPGLVPVVKGNGYGFTPGRLARKSEWLGVDTIAVGTYEELPGVASRFGGSLLVLTPWRPFVADLPPELAGRVIHTVGRVEDVDALLTRQPGARLVLELLTSMKRHGFTARGLWDAAEHLRRHRSARLEGVALHLPLAQGSHLGEVRRLMNDAVGAGLQHLGQPGPDGQPGRGGLDTVWVSHLTAGEQAALRTSYADFTIRPRMGTDLWLGDRAALTVTATVLDVHEVERGDSFGYRGRTVPKAGHLLVVSGGTAHGIGLEAPTGDSSIKARAATLARGGLDAVGFVRSPFSIDDKQRLFAEPPHMQASMLFLPSGARVPTVGDEIDVRVRYTATTFDRIVLS
>NZ_CP040695.2|WP_148240932.1|4399034_4400471_-|hypothetical-protein
MTHVDPTHDDPVVAGMSGAVGGPLGERAARGGAFSVLGVLLAITALTFALGLLTKTTCAQDDWSLQEADRFTHACSSEVADEYTGTGLVELAWPWSGEEATRDRYPVTDQPALVGLWTYATARVTYLLSGSPDVSERYRQPVTAVAQSDDAAGERSLFMAVNAVLLAGVAMLATAALAAVHRRRPWDAAGFAAAPVLALAGAISFDLLAVAAVAGALWAWSRGRGVLAGALVGVGAAAGFWPVLVLAAFLLVAATERRAAWVLPSAVTAVATWAVLNAPAFLTGRAQWERAWSATFERGADQGSVWRIVADTAGLATDVGLVVSWLLVALWTGLVVALVLLAPARARVSQVALLLVAGYALLGIAYEPRQALWLLPLAALARPRWRDLLVWQAGEVFFLAATSWWQGGLLSPGSGETAGFYWVAIVVRLVCTGWLVAVVVRDLWWPEADPVGDPETAPSGRSGDEAQDSTMRSNVVAV
>NZ_CP040695.2|WP_137294598.1|4400467_4402780_-|penicillin-binding-protein
MTWKRRVLKVVKWGFITGLVLTLVGIAGFIYLYKTTDIPEPNAELLTNATFVYYDDGETELGRFATQFRDSLTYEEMPQNIKDAVVAAEDQSFWTNSGIDPKGILRAVFNNASGGSQQGASTITQQYVKILYLTQERSYERKVKEAILSLKIQREYSKEQVLTGYLNTIYFGRGAYGIEAAADVYFNKKAADLTLRETAVLASVLNNPNGLDPADGKAVRLELKGRYEYVLGAMASEGYITDEDAEQARRKLPKFPEQDVEDSYGGQTGHALTLIKNQVLGLTNAETDAPFTEEEIDGGGLRITTTLTSKAMKAAEEGVEEVRPKGFPGAKDLHLAAATVEPGTGALRGFYAGQDFLDSQLNWAVAGGQAGSTFKPFAVAAGLKQGFALKDTFDGNSPYEIEGTDDEVENQGDEDYGSAVSLTSATENSINTAFIDLTIAMDDGPESIIETAESMGIPPAKAKRRGAYGIPTSSPGLEPVTGVALGSQTVSPINMANGYATVANEGVAADVHVISKVVNKAGDVLYEHKVTDERAISADIASDVSYAMQQVTEAGSGTRANLDDGRPIAGKTGTATKDGGAVSSSWFVGYTPQLSTAVMMVRGVGNGQLDDWVPSSEDGVDGYFGGNYPAKTWKAIMERDLEGVDPEDFPEPAFVDGEAPSDGHAPYTPPPAPSTTRQPPKTPSIDPNPPTSEPTQDPSPTQEPPPTQEPPPTSPPEPPETSTPPEPPQTSAPPTSPPAPAPPAGPPNPRERSRSPRRRPSRTRRAPAVR

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040695_4	4.2|418453|21|NZ_CP040695|CRISPRCasFinder	418453-418473	21	NZ_CP040695.2	2974878-2974898	2	0.905

1. spacer 4.2|418453|21|NZ_CP040695|CRISPRCasFinder matches to position: 2974878-2974898, mismatch: 2, identity: 0.905

cccggcggccagcagggctac	CRISPR spacer
cccgacggccagcagggccac	Protospacer
****.*************.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040695_4	4.2|418453|21|NZ_CP040695|CRISPRCasFinder	418453-418473	21	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	294661-294681	1	0.952
NZ_CP040695_2	2.1|89883|26|NZ_CP040695|CRISPRCasFinder	89883-89908	26	KJ433975	Mycobacterium phage 40BC, complete genome	68406-68431	3	0.885
NZ_CP040695_2	2.1|89883|26|NZ_CP040695|CRISPRCasFinder	89883-89908	26	KJ433973	Mycobacterium phage 39HC, complete genome	68406-68431	3	0.885
NZ_CP040695_2	2.1|89883|26|NZ_CP040695|CRISPRCasFinder	89883-89908	26	NC_024145	Mycobacterium phage Hosp, complete genome	65710-65735	3	0.885
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	314992-315019	4	0.857
NZ_CP040695_14	14.3|4103014|28|NZ_CP040695|CRISPRCasFinder	4103014-4103041	28	NZ_CP045722	Pantoea eucalypti strain LMG 24197 plasmid unnamed2, complete sequence	61773-61800	4	0.857
NZ_CP040695_14	14.3|4103014|28|NZ_CP040695|CRISPRCasFinder	4103014-4103041	28	NZ_CP022519	Pantoea vagans strain FBS135 plasmid pPant3, complete sequence	1736-1763	4	0.857
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	680315-680342	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2711001-2711028	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NC_009479	Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM2, complete sequence	11255-11282	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP027023	Streptomyces sp. WAC00288 plasmid p1, complete sequence	22438-22465	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP022220	Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence	957721-957748	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	195121-195148	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP030052	Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence	570561-570588	5	0.821
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP030054	Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence	750154-750181	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP021917	Sagittula sp. P11 plasmid unnamed4, complete sequence	22023-22050	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1064623-1064650	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_LR134447	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 5, complete sequence	81279-81306	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_LR134457	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 15, complete sequence	16238-16265	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	172595-172622	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	975078-975105	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	709796-709823	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	543136-543163	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	338812-338839	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	MF140416	Mycobacterium phage LastHope, complete genome	23173-23200	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1685312-1685339	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	465797-465824	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_LR134469	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence	17925-17952	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1502835-1502862	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1685449-1685476	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	310148-310175	5	0.821
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP049906	Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence	750773-750800	5	0.821
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1508967-1508994	5	0.821
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	149551-149578	5	0.821
NZ_CP040695_2	2.2|89933|27|NZ_CP040695|CRISPRCasFinder	89933-89959	27	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	911409-911435	6	0.778
NZ_CP040695_2	2.2|89933|27|NZ_CP040695|CRISPRCasFinder	89933-89959	27	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	513169-513195	6	0.778
NZ_CP040695_2	2.2|89933|27|NZ_CP040695|CRISPRCasFinder	89933-89959	27	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	170425-170451	6	0.778
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	MK279905	Mycobacterium phage Acquire49, complete genome	42982-43009	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	MK310144	Mycobacterium phage CicholasNage, complete genome	43018-43045	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	JN600672	Mycobacterium phage Fezzik, complete genome	43328-43355	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	MN586018	Mycobacterium phage Wyatt2, complete genome	43317-43344	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	MK494092	Mycobacterium phage Silverleaf, complete genome	43052-43079	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	MN096382	Mycobacterium phage AvadaKedavra, complete genome	43055-43082	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	NC_042313	Mycobacterium virus JoeDirt, complete genome	43297-43324	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	MT771349	Mycobacterium phage Tyson, complete genome	43319-43346	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	161657-161684	6	0.786
NZ_CP040695_14	14.1|4102906|28|NZ_CP040695|CRISPRCasFinder	4102906-4102933	28	KU160669	Arthrobacter phage Tank, complete genome	64570-64597	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	853966-853993	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP033971	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence	326111-326138	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_LR134466	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 24, complete sequence	19148-19175	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	379676-379703	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP006368	Aureimonas sp. AU20 plasmid pAU20a, complete sequence	334246-334273	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP006370	Aureimonas sp. AU20 plasmid pAU20c, complete sequence	210119-210146	6	0.786
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	634808-634835	6	0.786
NZ_CP040695_14	14.3|4103014|28|NZ_CP040695|CRISPRCasFinder	4103014-4103041	28	NZ_CP011518	Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence	277006-277033	6	0.786
NZ_CP040695_14	14.3|4103014|28|NZ_CP040695|CRISPRCasFinder	4103014-4103041	28	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	220084-220111	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	327196-327223	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4211122-4211149	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	258101-258128	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	184669-184696	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	594946-594973	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1548641-1548668	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP030371	Salinibacter ruber strain RM158 plasmid pSR60, complete sequence	32186-32213	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1170422-1170449	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1638838-1638865	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	174427-174454	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	437632-437659	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	530405-530432	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	149593-149620	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	309559-309586	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP030363	Salinibacter ruber strain SP73 plasmid pSR118, complete sequence	89393-89420	6	0.786
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	479423-479450	6	0.786
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5326502-5326529	6	0.786
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5519046-5519073	6	0.786
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NZ_AP020327	Mycobacterium avium subsp. hominissuis strain JP-H-1 plasmid p1-JPH1	145304-145331	6	0.786
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	1011986-1012013	6	0.786
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_008271	Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence	319218-319248	6	0.806
NZ_CP040695_7	7.1|1041919|37|NZ_CP040695|CRISPRCasFinder	1041919-1041955	37	NZ_CP018865	Arthrobacter crystallopoietes strain DSM 20117 plasmid pLDW-10, complete sequence	208383-208419	7	0.811
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	480966-480993	7	0.75
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP046330	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed1, complete sequence	75959-75986	7	0.75
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	12385-12412	7	0.75
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_CP044066	Cupriavidus pauculus strain FDAARGOS_664 plasmid unnamed1, complete sequence	220073-220100	7	0.75
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	470748-470775	7	0.75
NZ_CP040695_14	14.2|4102960|28|NZ_CP040695|CRISPRCasFinder	4102960-4102987	28	NC_006525	Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence	30733-30760	7	0.75
NZ_CP040695_14	14.3|4103014|28|NZ_CP040695|CRISPRCasFinder	4103014-4103041	28	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	403041-403068	7	0.75
NZ_CP040695_14	14.3|4103014|28|NZ_CP040695|CRISPRCasFinder	4103014-4103041	28	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	480293-480320	7	0.75
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	67219-67246	7	0.75
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_LR134458	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 16, complete sequence	11188-11215	7	0.75
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	692430-692457	7	0.75
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP032053	Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence	69036-69063	7	0.75
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP054620	Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence	24710-24737	7	0.75
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP026654	Streptomyces dengpaensis strain XZHG99 plasmid unnamed2, complete sequence	4773-4800	7	0.75
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	AP017627	Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome	33875-33902	7	0.75
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	NZ_CP031094	Hydrocarboniclastica marina strain soil36-7 plasmid psoil36-7, complete sequence	108837-108864	7	0.75
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	400959-400986	7	0.75
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	1540438-1540465	7	0.75
NZ_CP040695_14	14.6|4103176|28|NZ_CP040695|CRISPRCasFinder	4103176-4103203	28	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	38491-38518	7	0.75
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_AP022578	Mycolicibacterium aubagnense strain JCM 15296 plasmid pJCM15296, complete sequence	103147-103177	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP025432	Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence	177682-177712	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	658732-658762	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	619448-619478	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1454713-1454743	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	655187-655217	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH590593	Mycobacterium phage Rabinovish, complete genome	108954-108984	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK112554	Mycobacterium phage TinyTim, complete genome	107437-107467	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359314	Mycobacterium phage Ewok, complete genome	108381-108411	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359337	Mycobacterium phage Flabslab, complete genome	106426-106456	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MN234193	Mycobacterium phage Kboogie, complete genome	107804-107834	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH779502	Mycobacterium phage FudgeTart, complete genome	107528-107558	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359365	Mycobacterium phage Loanshark, complete genome	107912-107942	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359364	Mycobacterium phage ChickenPhender, complete genome	107009-107039	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK112549	Mycobacterium phage Morizzled23, complete genome	106717-106747	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK112541	Mycobacterium phage Jessibeth14, complete genome	109130-109160	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK450425	Mycobacterium phage Shelob, complete genome	109962-109992	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_023714	Mycobacterium phage LinStu, complete genome	108089-108119	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KJ595575	Mycobacterium phage Willis, complete genome	108248-108278	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359333	Mycobacterium phage JustHall, complete genome	107146-107176	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KT321476	Mycobacterium phage Zeenon, complete genome	108648-108678	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MN428065	Mycobacterium phage Cactojaque, complete genome	106882-106912	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359306	Mycobacterium phage Norm, complete genome	108788-108818	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	JN699625	Mycobacterium phage Wally, complete genome	107334-107364	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	EU826471	Mycobacterium phage Cali, complete genome	108829-108859	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KX721255	Mycobacterium phage Yucca, complete genome	108996-109026	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359366	Mycobacterium phage Basquiat, complete genome	106862-106892	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359346	Mycobacterium phage NoodleTree, complete genome	108786-108816	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH779498	Mycobacterium phage Bread, complete genome	107453-107483	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	GQ303262	Mycobacterium phage LRRHood, complete genome	107802-107832	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MT818423	Mycobacterium phage Janiyra, complete genome	108239-108269	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH316567	Mycobacterium phage ParkTD, complete genome	108350-108380	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KX721256	Mycobacterium phage Erdmann, complete genome	108462-108492	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KM881426	Mycobacterium phage ZygoTaiga	109268-109298	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MT889395	Mycobacterium phage Shifa, complete genome	107573-107603	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	EU826467	Mycobacterium phage Rizal, complete genome	106306-106336	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MT723944	Mycobacterium phage ChaylaJr, complete genome	107290-107320	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH910040	Mycobacterium phage Sauce, complete genome	107005-107035	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK112548	Mycobacterium phage McWolfish, complete genome	107808-107838	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359308	Mycobacterium phage Shaqnato, complete genome	107222-107252	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK112545	Mycobacterium phage Khaleesi, complete genome	108597-108627	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359350	Mycobacterium phage Nidhogg, complete genome	108879-108909	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MT723945	Mycobacterium phage Quasimodo, complete genome	108679-108709	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK112533	Mycobacterium phage Bonray, complete genome	109455-109485	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359327	Mycobacterium phage EmToTheThree, complete genome	108504-108534	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH727543	Mycobacterium phage CharlieB, complete genome	107590-107620	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359336	Mycobacterium phage Chargie21, complete genome	106862-106892	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359355	Mycobacterium phage Sprinklers, complete genome	107712-107742	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MF919499	Mycobacterium phage Daffodil, complete genome	108353-108383	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359334	Mycobacterium phage Delilah, complete genome	108471-108501	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_023696	Mycobacterium phage Dandelion, complete genome	111986-112016	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MN276192	Mycobacterium phage Trinitium, complete genome	107184-107214	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH825713	Mycobacterium phage Zalkecks, complete genome	108077-108107	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359349	Mycobacterium phage FoxtrotP1, complete genome	109061-109091	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	JF704096	Mycobacterium phage Ghost, complete sequence	107261-107291	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MN062707	Mycobacterium phage Grungle, complete genome	105298-105328	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359344	Mycobacterium phage Napoleon13, complete genome	107081-107111	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359363	Mycobacterium phage Fludd, complete genome	107817-107847	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KX831080	Mycobacterium phage Lukilu, complete genome	108812-108842	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	JQ911768	Mycobacterium phage Ava3, complete genome	107784-107814	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_011270	Mycobacterium phage Spud, complete genome	107424-107454	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359345	Mycobacterium phage QBert, complete genome	107409-107439	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	GQ303260	Mycobacterium phage ET08, complete genome	107624-107654	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH744422	Mycobacterium phage Roots515, complete genome	109607-109637	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK359321	Mycobacterium phage Phusco, complete genome	106885-106915	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	EU826469	Mycobacterium phage ScottMcG, complete genome	106812-106842	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK310143	Mycobacterium phage Dietrick, complete genome	106592-106622	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK450429	Mycobacterium phage Bipolarisk, complete genome	108053-108083	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH051266	Mycobacterium phage MikeLiesIn, complete genome	109235-109265	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MH669008	Mycobacterium phage Megamind, complete genome	108099-108129	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK878897	Mycobacterium phage Blackbrain, complete genome	107947-107977	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK450434	Mycobacterium phage DrPhinkDaddy, complete genome	109131-109161	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MF919527	Mycobacterium phage Phox, complete genome	109008-109038	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MT818416	Mycobacterium phage BackyardAgain, complete genome	106036-106066	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MF919494	Mycobacterium phage BeanWater, complete genome	107388-107418	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_028869	Mycobacterium phage HyRo, complete genome	107604-107634	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KT365400	Mycobacterium phage ErnieJ, complete genome	106284-106314	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	KC748968	Mycobacterium phage Gizmo, complete genome	110379-110409	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MT553335	Mycobacterium phage Ronan, complete genome	106491-106521	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	DQ398053	Mycobacteriophage Catera, complete genome	106563-106593	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MF919513	Mycobacterium phage Koguma, complete genome	107457-107487	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	JN204348	Mycobacterium phage Sebata, complete genome	109514-109544	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MN183285	Mycobacterium phage YoungMoneyMata, complete genome	107546-107576	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MK450423	Mycobacterium phage Stubby, complete genome	107464-107494	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	MF919493	Mycobacterium phage Audrick, complete genome	107240-107270	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_008207	Mycobacterium phage Catera, complete genome	106563-106593	7	0.774
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	JN624850	Mycobacterium phage Pleione, complete genome	108828-108858	7	0.774
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	468204-468231	8	0.714
NZ_CP040695_14	14.4|4103068|28|NZ_CP040695|CRISPRCasFinder	4103068-4103095	28	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	586307-586334	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	797213-797240	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	796762-796789	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	KC139653	Salmonella phage FSL SP-038 putative phage replicative helicase/primease and hypothetical protein genes, complete cds; and hypothetical protein gene, partial cds	1976-2003	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	KC139518	Salmonella phage FSL SP-031, complete genome	13372-13399	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	KC139559	Salmonella phage FSL SP-049 hypothetical protein, helicase, hypothetical proteins, DNA polymerase I, Mom, hypothetical protein, endonuclease, hypothetical proteins, putative HNH endonuclease, putative phage replicative helicase/primease, hypothetical proteins, lysozyme, hypothetical proteins, phage structural protein, head morphogenesis protein, and hypothetical protein genes, complete cds	13839-13866	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	MH424444	Salmonella virus VSiP, complete genome	36751-36778	8	0.714
NZ_CP040695_14	14.5|4103122|28|NZ_CP040695|CRISPRCasFinder	4103122-4103149	28	MN070121	Salmonella phage Shemara, complete genome	37792-37819	8	0.714
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_011879	Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence	311796-311826	8	0.742
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP025409	Paracoccus sp. BM15 plasmid pBM151, complete sequence	92419-92449	8	0.742
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP021915	Sagittula sp. P11 plasmid unnamed2, complete sequence	145236-145266	8	0.742
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP010856	Marinovum algicola DG 898 plasmid pMaD1, complete sequence	148791-148821	8	0.742
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP018081	Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence	118327-118357	8	0.742
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1065151-1065181	8	0.742
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP006990	Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence	240643-240674	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP013600	Rhizobium sp. N741 plasmid pRspN741e, complete sequence	342243-342274	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP013504	Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence	342243-342274	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP013510	Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence	340684-340715	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP013521	Rhizobium sp. N113 plasmid pRspN113d, complete sequence	344931-344962	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP021127	Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence	227290-227321	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP013494	Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence	339049-339080	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP013594	Rhizobium sp. N871 plasmid pRspN871d, complete sequence	342243-342274	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	239768-239799	8	0.75
NZ_CP040695_18	18.1|4391498|32|NZ_CP040695|CRISPRCasFinder	4391498-4391529	32	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	171602-171633	8	0.75
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_LR134457	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 15, complete sequence	1359-1389	9	0.71
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	CP000663	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence	232707-232737	9	0.71
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	544280-544310	9	0.71
NZ_CP040695_14	14.7|4103230|31|NZ_CP040695|CRISPRCasFinder	4103230-4103260	31	NZ_CP031752	Rhodobacter sphaeroides strain EBL0706 plasmid p.A, complete sequence	230140-230170	9	0.71

1. spacer 4.2|418453|21|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 1, identity: 0.952

cccggcggccagcagggctac	CRISPR spacer
cccggcggccagcacggctac	Protospacer
************** ******

2. spacer 2.1|89883|26|NZ_CP040695|CRISPRCasFinder matches to KJ433975 (Mycobacterium phage 40BC, complete genome) position: , mismatch: 3, identity: 0.885

cgtgggccggtccgacccgagtgatc	CRISPR spacer
ggtaggccggtccgccccgagtgatc	Protospacer
 **.********** ***********

3. spacer 2.1|89883|26|NZ_CP040695|CRISPRCasFinder matches to KJ433973 (Mycobacterium phage 39HC, complete genome) position: , mismatch: 3, identity: 0.885

cgtgggccggtccgacccgagtgatc	CRISPR spacer
ggtaggccggtccgccccgagtgatc	Protospacer
 **.********** ***********

4. spacer 2.1|89883|26|NZ_CP040695|CRISPRCasFinder matches to NC_024145 (Mycobacterium phage Hosp, complete genome) position: , mismatch: 3, identity: 0.885

cgtgggccggtccgacccgagtgatc	CRISPR spacer
ggtaggccggtccgccccgagtgatc	Protospacer
 **.********** ***********

5. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 4, identity: 0.857

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
ggcgcgtcgccggcgcgggcctggcgga	Protospacer
.* .********************.***

6. spacer 14.3|4103014|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP045722 (Pantoea eucalypti strain LMG 24197 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.857

tctcggtcaccgggtcgctgcgcgtcaa	CRISPR spacer
ggtcggtcaccgagtcgctgcgcgacaa	Protospacer
  **********.*********** ***

7. spacer 14.3|4103014|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP022519 (Pantoea vagans strain FBS135 plasmid pPant3, complete sequence) position: , mismatch: 4, identity: 0.857

tctcggtcaccgggtcgctgcgcgtcaa	CRISPR spacer
ggtcggtcaccgagtcgctgcgcgacaa	Protospacer
  **********.*********** ***

8. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 5, identity: 0.821

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
ccggccccatcggcacctgcccccgtgg	Protospacer
***** *************** **   *

9. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
tcgacgtcgccggcgcgggccaggtcgc	Protospacer
  ******************* *** * 

10. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NC_009479 (Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM2, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
aggacgtcgccggcgcggacctcgtact	Protospacer
******************.*** **.  

11. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP027023 (Streptomyces sp. WAC00288 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
agctcgtcgccggcgcggggctgctggc	Protospacer
**  *************** *** *** 

12. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP022220 (Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
acggcgtcgccggcgcgggccttgtcca	Protospacer
* *.****************** **  *

13. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
aggaggccgccggcgcgggcctgctcgg	Protospacer
**** *.**************** * *.

14. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP030052 (Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
acggcgtcgccggcgcgggccttgtcca	Protospacer
* *.****************** **  *

15. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP030054 (Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.821

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
acggcgtcgccggcgcgggccttgtcca	Protospacer
* *.****************** **  *

16. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP021917 (Sagittula sp. P11 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgcgggcagcgccgtcgcggtggt	Protospacer
*************** **.******  .

17. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgcgagcggcgacgccgcggtgat	Protospacer
********.**.*************  .

18. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_LR134447 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 5, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
cgaccgcgggcaccgacgccgcgggcgc	Protospacer
  ********** *********** * *

19. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_LR134457 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 15, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ggtcgtcgggcagcgacgccgcggtgtc	Protospacer
*  *  ******************* **

20. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcgaggcgcgcagcggcgccgcggtctc	Protospacer
**.  *** ******.************

21. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gccgcaggggcagcgacaccgcggtctc	Protospacer
**  *. **********.**********

22. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgcgggcagcgacgccaaggattt	Protospacer
********************. ** .*.

23. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ccaccgcgggcagcgccgccgcgcccgc	Protospacer
 ************** ******* .* *

24. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgcgggcagcgacgccaaggattt	Protospacer
********************. ** .*.

25. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to MF140416 (Mycobacterium phage LastHope, complete genome) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gtaccgcgggcagcggcgccacggtcgg	Protospacer
*.*************.****.*****  

26. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.821

-gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
cgca-tgcgcgcagcgacgccgcggtcct	Protospacer
 *** .*** *****************..

27. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.821

-gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
cgca-tgcgcgcagcgacgccgcggtcct	Protospacer
 *** .*** *****************..

28. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_LR134469 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 27, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ccaccgcgggccgcgacgccgaggaccc	Protospacer
 ********** ********* ** *.*

29. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 5, identity: 0.821

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
tcaacgcgcgcagcgacgccgcggccgc	Protospacer
 ** **** ***************.* *

30. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.821

-gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
cgca-tgcgcgcagcgacgccgcggtcct	Protospacer
 *** .*** *****************..

31. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.821

-gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
cgca-tgcgcgcagcgacgccgcggtcct	Protospacer
 *** .*** *****************..

32. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP049906 (Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.821

gcac-cgcgggcagcgacgccgcggtctc	CRISPR spacer
-cacaggcgggcagcgacgctgcggtcaa	Protospacer
 ***  **************.******  

33. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 5, identity: 0.821

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
gcgcaacgaacggcgccacggccctcag	Protospacer
*** . ***************** ***.

34. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 5, identity: 0.821

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
gccaggccctcaccgacggcggccacga	Protospacer
********* ******** ***** *. 

35. spacer 2.2|89933|27|NZ_CP040695|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 6, identity: 0.778

tccgggccgacgcgaccgggagaaact	CRISPR spacer
atcgggccgacccgaccgggaggaagc	Protospacer
 .********* **********.** .

36. spacer 2.2|89933|27|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 6, identity: 0.778

tccgggccgacgcgaccgggagaaact	CRISPR spacer
atcgggccgacccgaccgggaggaagc	Protospacer
 .********* **********.** .

37. spacer 2.2|89933|27|NZ_CP040695|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 6, identity: 0.778

tccgggccgacgcgaccgggagaaact	CRISPR spacer
atcgggccgacccgaccgggaggaagc	Protospacer
 .********* **********.** .

38. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to MK279905 (Mycobacterium phage Acquire49, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

39. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to MK310144 (Mycobacterium phage CicholasNage, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

40. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to JN600672 (Mycobacterium phage Fezzik, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

41. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to MN586018 (Mycobacterium phage Wyatt2, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

42. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to MK494092 (Mycobacterium phage Silverleaf, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

43. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to MN096382 (Mycobacterium phage AvadaKedavra, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

44. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to NC_042313 (Mycobacterium virus JoeDirt, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

45. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to MT771349 (Mycobacterium phage Tyson, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
gtgtcttcatcggcaccggccacctgcg	Protospacer
 .* * .********** **********

46. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
cctgccccatcggcacctgccacgggtt	Protospacer
** ** *****************  *. 

47. spacer 14.1|4102906|28|NZ_CP040695|CRISPRCasFinder matches to KU160669 (Arthrobacter phage Tank, complete genome) position: , mismatch: 6, identity: 0.786

ccggcaccatcggcacctgccacctgcg	CRISPR spacer
ccggcaccctcggcaccggccacggcca	Protospacer
******** ******** *****   *.

48. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
gtgccgtcgccggcgcgggcgtggcggg	Protospacer
. * **************** ***.**.

49. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP033971 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
gcgacgtcgccggcgcgggcctgcgcgc	Protospacer
. *********************   * 

50. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_LR134466 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 24, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
tcgacggcgccggcgcgggccaggtgcg	Protospacer
  **** ************** **** .

51. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
aggacgtcgccgtcgccggcctgggtct	Protospacer
************ *** *******    

52. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP006368 (Aureimonas sp. AU20 plasmid pAU20a, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
aggacgtcgccggcgcgcgcctccgtgc	Protospacer
***************** ****    * 

53. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP006370 (Aureimonas sp. AU20 plasmid pAU20c, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
gcctcgtcgccgtcgcggccctggtgga	Protospacer
.   ******** ***** *********

54. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
tggcgttcgcctgcgcgggcctggtggg	Protospacer
 **   ***** ***************.

55. spacer 14.3|4103014|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP011518 (Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence) position: , mismatch: 6, identity: 0.786

tctcggtcaccgggtcgctgcgcgtcaa	CRISPR spacer
gcaaggtcaccgggtcgccgcgggtcag	Protospacer
 *  **************.*** ****.

56. spacer 14.3|4103014|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

tctcggtcaccgggtcgctgcgcgtcaa	CRISPR spacer
cgttggtcaccgggtcggtgcccgtcag	Protospacer
. *.************* *** *****.

57. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgccggcagcgacggcgcgtcgcc	Protospacer
******* ********** **** . .*

58. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ccacctcgggcagcgacgccacgggcag	Protospacer
 **** **************.*** *  

59. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgcgcgcagcgtcgccgcggcgag	Protospacer
******** ****** ********.   

60. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcgtgacgtgcagcgacgccgcggtctg	Protospacer
**.. .** ****************** 

61. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ccaccgcgggcagcgccgcggcggcagc	Protospacer
 ************** *** ****.  *

62. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
tcaacgcgcgcagcgacgccgcggcggc	Protospacer
 ** **** ***************.  *

63. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP030371 (Salinibacter ruber strain RM158 plasmid pSR60, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
tcaccgccagcagcgacgccgcggccat	Protospacer
 ****** .***************.* .

64. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
tcaacgcgcgcagcgacgccgcggcggc	Protospacer
 ** **** ***************.  *

65. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ccgccgcgggcagcgccgccgcgctcga	Protospacer
 *.************ ******* **  

66. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
ccgccgcgggcagcgccgccgcgctcga	Protospacer
 *.************ ******* **  

67. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gccagccgggcagcgacgtcgcggtctt	Protospacer
**    ************.********.

68. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gccagccgggcagcgacgtcgcggtctt	Protospacer
**    ************.********.

69. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcggcgcgggcggcgacgccgcggtgat	Protospacer
**. *******.*************  .

70. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gccagccgggcagcgacgtcgcggtctt	Protospacer
**    ************.********.

71. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP030363 (Salinibacter ruber strain SP73 plasmid pSR118, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
tcaccgccagcagcgacgccgcggccat	Protospacer
 ****** .***************.* .

72. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 6, identity: 0.786

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgcgggcagccccgccgcgcgtgc	Protospacer
**************  *******  . *

73. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
cggagtcgaacgacgccacgaccgtgca	Protospacer
  **********.*******.****  *

74. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.786

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
tgcaggcccgcaccgacttcggcgccat	Protospacer
  *************** ***** .**.

75. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP020327 (Mycobacterium avium subsp. hominissuis strain JP-H-1 plasmid p1-JPH1) position: , mismatch: 6, identity: 0.786

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
ctcgcgccggcaccgacgtcggccgcac	Protospacer
 .*. *** *************** ***

76. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.786

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
tcgccgccggcaacgacgtcggcctcac	Protospacer
 *   *** *** ***************

77. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_008271 (Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence) position: , mismatch: 6, identity: 0.806

cctcggtcagcgccggccgggtgcaggtcaa--	CRISPR spacer
acccggtcagcggcggacgggtgcag--caatc	Protospacer
 *.********* *** *********  ***  

78. spacer 7.1|1041919|37|NZ_CP040695|CRISPRCasFinder matches to NZ_CP018865 (Arthrobacter crystallopoietes strain DSM 20117 plasmid pLDW-10, complete sequence) position: , mismatch: 7, identity: 0.811

tgacgcggatcccggt-----cgtcgccgacgcggatcccgg	CRISPR spacer
-----cggaccccggtccggccgtcgtcgacgcggatcccgg	Protospacer
     ****.******     *****.***************

79. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.75

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
tctacgtcgtcgtcgcgggcctggtgtg	Protospacer
   ******.** ************* .

80. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP046330 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.75

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
gcgacgttgccggcgcgggcctgcgtgc	Protospacer
. *****.***************   * 

81. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 7, identity: 0.75

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
atctgcccgcgggcgcgggcctggtgga	Protospacer
*     .*** *****************

82. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP044066 (Cupriavidus pauculus strain FDAARGOS_664 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.75

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
gcgacgtcgccggcgcgggtctgcgcgc	Protospacer
. *****************.***   * 

83. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 7, identity: 0.75

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
tctacgtcgccggcgcggggctggcgcg	Protospacer
   **************** ****.* .

84. spacer 14.2|4102960|28|NZ_CP040695|CRISPRCasFinder matches to NC_006525 (Cupriavidus metallidurans CH34 plasmid pMOL28, complete sequence) position: , mismatch: 7, identity: 0.75

aggacgtcgccggcgcgggcctggtgga	CRISPR spacer
gcgacgttgccggcgcgggcctgcgtgc	Protospacer
. *****.***************   * 

85. spacer 14.3|4103014|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.75

tctcggtcaccgggtcgctgcgcgtcaa	CRISPR spacer
tctcggtcatcgggtagctgcgcacgcc	Protospacer
*********.***** *******..   

86. spacer 14.3|4103014|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.75

tctcggtcaccgggtcgctgcgcgtcaa	CRISPR spacer
ccgtcaccatcgggtcgctgcgcgtcaa	Protospacer
.* . ..**.******************

87. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 7, identity: 0.75

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccccgggcagcggcgccgcgcgtgt	Protospacer
***** *********.*******  . .

88. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_LR134458 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 16, complete sequence) position: , mismatch: 7, identity: 0.75

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
cgcccgcgggcacggacgccgcggtcct	Protospacer
   *********  ************..

89. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.75

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcgccgcgggcagcgccgccgcgtcggt	Protospacer
**.************ ******* .  .

90. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032053 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL2, complete sequence) position: , mismatch: 7, identity: 0.75

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgccgtcagcgacgccgcgcggag	Protospacer
******* * *************     

91. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP054620 (Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.75

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gtgatgcgggcggcgacgccgcggtcga	Protospacer
*.. .******.**************  

92. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP026654 (Streptomyces dengpaensis strain XZHG99 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.75

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
gcaccgccggcagcggcgccgcgaagag	Protospacer
******* *******.*******.    

93. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to AP017627 (Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome) position: , mismatch: 7, identity: 0.75

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
cggccgcgaacggcgccacggccgacag	Protospacer
  *   ****************** **.

94. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP031094 (Hydrocarboniclastica marina strain soil36-7 plasmid psoil36-7, complete sequence) position: , mismatch: 7, identity: 0.75

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
cgccgtcgaatgacgccacggccgtcat	Protospacer
    ******.*.************** 

95. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 7, identity: 0.75

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
cccaggaccgcatcgacgtcggccaacg	Protospacer
 ***** *****.***********    

96. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.75

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
atgtggccggcaccgatgtcggcctcag	Protospacer
..  **** *******.********** 

97. spacer 14.6|4103176|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 7, identity: 0.75

gccaggcccgcaccgacgtcggcctcac	CRISPR spacer
cgcaggccggcaccgacctcggcctgct	Protospacer
  ****** ******** *******  .

98. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_AP022578 (Mycolicibacterium aubagnense strain JCM 15296 plasmid pJCM15296, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cctcggtcagcgccggctgggtgagccgaaa	Protospacer
*****************.***** .    **

99. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP025432 (Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cctcggtcagcgccagccgggtggcgatgcc	Protospacer
**************.********  *.*   

100. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cggcgatcatcgccggccgggtgcaggcgat	Protospacer
*  **.*** *****************. * 

101. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cggcgatcatcgccggccgggtgcaggcgat	Protospacer
*  **.*** *****************. * 

102. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cggcgatcatcgccggccgggtgcaggcgat	Protospacer
*  **.*** *****************. * 

103. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
ccgagcgcagcgccggccggctgccggtcat	Protospacer
**  *  ************* *** ***** 

104. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH590593 (Mycobacterium phage Rabinovish, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

105. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK112554 (Mycobacterium phage TinyTim, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

106. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359314 (Mycobacterium phage Ewok, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

107. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359337 (Mycobacterium phage Flabslab, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

108. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MN234193 (Mycobacterium phage Kboogie, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

109. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH779502 (Mycobacterium phage FudgeTart, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

110. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359365 (Mycobacterium phage Loanshark, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

111. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359364 (Mycobacterium phage ChickenPhender, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

112. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK112549 (Mycobacterium phage Morizzled23, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

113. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK112541 (Mycobacterium phage Jessibeth14, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

114. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK450425 (Mycobacterium phage Shelob, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

115. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_023714 (Mycobacterium phage LinStu, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

116. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KJ595575 (Mycobacterium phage Willis, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

117. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359333 (Mycobacterium phage JustHall, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

118. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KT321476 (Mycobacterium phage Zeenon, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

119. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MN428065 (Mycobacterium phage Cactojaque, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

120. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359306 (Mycobacterium phage Norm, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

121. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to JN699625 (Mycobacterium phage Wally, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

122. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to EU826471 (Mycobacterium phage Cali, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

123. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KX721255 (Mycobacterium phage Yucca, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

124. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359366 (Mycobacterium phage Basquiat, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

125. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359346 (Mycobacterium phage NoodleTree, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

126. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH779498 (Mycobacterium phage Bread, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

127. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to GQ303262 (Mycobacterium phage LRRHood, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

128. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MT818423 (Mycobacterium phage Janiyra, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

129. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH316567 (Mycobacterium phage ParkTD, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

130. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KX721256 (Mycobacterium phage Erdmann, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

131. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KM881426 (Mycobacterium phage ZygoTaiga) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

132. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MT889395 (Mycobacterium phage Shifa, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

133. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to EU826467 (Mycobacterium phage Rizal, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

134. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MT723944 (Mycobacterium phage ChaylaJr, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

135. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH910040 (Mycobacterium phage Sauce, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

136. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK112548 (Mycobacterium phage McWolfish, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

137. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359308 (Mycobacterium phage Shaqnato, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

138. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK112545 (Mycobacterium phage Khaleesi, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

139. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359350 (Mycobacterium phage Nidhogg, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

140. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MT723945 (Mycobacterium phage Quasimodo, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

141. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK112533 (Mycobacterium phage Bonray, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

142. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359327 (Mycobacterium phage EmToTheThree, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

143. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH727543 (Mycobacterium phage CharlieB, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

144. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359336 (Mycobacterium phage Chargie21, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

145. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359355 (Mycobacterium phage Sprinklers, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

146. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MF919499 (Mycobacterium phage Daffodil, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

147. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359334 (Mycobacterium phage Delilah, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

148. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_023696 (Mycobacterium phage Dandelion, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

149. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MN276192 (Mycobacterium phage Trinitium, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

150. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH825713 (Mycobacterium phage Zalkecks, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

151. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359349 (Mycobacterium phage FoxtrotP1, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

152. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to JF704096 (Mycobacterium phage Ghost, complete sequence) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

153. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MN062707 (Mycobacterium phage Grungle, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

154. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359344 (Mycobacterium phage Napoleon13, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

155. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359363 (Mycobacterium phage Fludd, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

156. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KX831080 (Mycobacterium phage Lukilu, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

157. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to JQ911768 (Mycobacterium phage Ava3, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

158. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_011270 (Mycobacterium phage Spud, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

159. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359345 (Mycobacterium phage QBert, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

160. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to GQ303260 (Mycobacterium phage ET08, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

161. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH744422 (Mycobacterium phage Roots515, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

162. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK359321 (Mycobacterium phage Phusco, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

163. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to EU826469 (Mycobacterium phage ScottMcG, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

164. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK310143 (Mycobacterium phage Dietrick, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

165. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK450429 (Mycobacterium phage Bipolarisk, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

166. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH051266 (Mycobacterium phage MikeLiesIn, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

167. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MH669008 (Mycobacterium phage Megamind, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

168. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK878897 (Mycobacterium phage Blackbrain, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

169. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK450434 (Mycobacterium phage DrPhinkDaddy, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

170. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MF919527 (Mycobacterium phage Phox, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

171. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MT818416 (Mycobacterium phage BackyardAgain, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

172. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MF919494 (Mycobacterium phage BeanWater, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

173. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_028869 (Mycobacterium phage HyRo, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

174. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KT365400 (Mycobacterium phage ErnieJ, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

175. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to KC748968 (Mycobacterium phage Gizmo, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

176. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MT553335 (Mycobacterium phage Ronan, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

177. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to DQ398053 (Mycobacteriophage Catera, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

178. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MF919513 (Mycobacterium phage Koguma, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

179. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to JN204348 (Mycobacterium phage Sebata, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

180. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MN183285 (Mycobacterium phage YoungMoneyMata, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

181. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MK450423 (Mycobacterium phage Stubby, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

182. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to MF919493 (Mycobacterium phage Audrick, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

183. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_008207 (Mycobacterium phage Catera, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

184. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to JN624850 (Mycobacterium phage Pleione, complete genome) position: , mismatch: 7, identity: 0.774

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tctcggccagcgccagccgggtgccgcgcag	Protospacer
.*****.*******.********* *  **.

185. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 8, identity: 0.714

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
agcgggcgggcagcgacgtcgcggtcca	Protospacer
.    *************.*******. 

186. spacer 14.4|4103068|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 8, identity: 0.714

gcaccgcgggcagcgacgccgcggtctc	CRISPR spacer
tgggaatgggcagcgtcgccgcggtctc	Protospacer
  .  ..******** ************

187. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
ttttgtcgaacgacgccacggccgtggt	Protospacer
 .  ********.************ . 

188. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
ttttgtcgaacgacgccacggccgtggt	Protospacer
 .  ********.************ . 

189. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to KC139653 (Salmonella phage FSL SP-038 putative phage replicative helicase/primease and hypothetical protein genes, complete cds; and hypothetical protein gene, partial cds) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
tcgagtcgaacggcgccagggctacggg	Protospacer
 ***************** ***... ..

190. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to KC139518 (Salmonella phage FSL SP-031, complete genome) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
tcgagtcgaacggcgccagggctacggg	Protospacer
 ***************** ***... ..

191. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to KC139559 (Salmonella phage FSL SP-049 hypothetical protein, helicase, hypothetical proteins, DNA polymerase I, Mom, hypothetical protein, endonuclease, hypothetical proteins, putative HNH endonuclease, putative phage replicative helicase/primease, hypothetical proteins, lysozyme, hypothetical proteins, phage structural protein, head morphogenesis protein, and hypothetical protein genes, complete cds) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
tcgagtcgaacggcgccagggctacggg	Protospacer
 ***************** ***... ..

192. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to MH424444 (Salmonella virus VSiP, complete genome) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
tcgagtcgaacggcgccagggctacggg	Protospacer
 ***************** ***... ..

193. spacer 14.5|4103122|28|NZ_CP040695|CRISPRCasFinder matches to MN070121 (Salmonella phage Shemara, complete genome) position: , mismatch: 8, identity: 0.714

gcgagtcgaacggcgccacggccgtcaa	CRISPR spacer
tcgagtcgaacggcgccagggcgacagg	Protospacer
 ***************** *** .. ..

194. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_011879 (Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence) position: , mismatch: 8, identity: 0.742

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
gttcgggcagcgccggccgggtgcggtggta	Protospacer
 .**** *****************.*    *

195. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP025409 (Paracoccus sp. BM15 plasmid pBM151, complete sequence) position: , mismatch: 8, identity: 0.742

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cctcggtcagggccagccgggtggatatgcc	Protospacer
********** ***.******** * .*   

196. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP021915 (Sagittula sp. P11 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

cctcggtcagcgccggccgggtgcaggtcaa--	CRISPR spacer
tctcggacagccccggccgggtgc--gccggct	Protospacer
.***** **** ************  *.*..  

197. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP010856 (Marinovum algicola DG 898 plasmid pMaD1, complete sequence) position: , mismatch: 8, identity: 0.742

cctcggtcagcgccggccgggtgcaggtcaa--	CRISPR spacer
tctcggacagccccggccgggtgc--gccggct	Protospacer
.***** **** ************  *.*..  

198. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP018081 (Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.742

cctcggtcagcgccggccgggtgcaggtcaa--	CRISPR spacer
tctcggacagccccggccgggtgc--gccggct	Protospacer
.***** **** ************  *.*..  

199. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 8, identity: 0.742

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
cctcggtcagcgccatccgggtggcggagct	Protospacer
**************. *******  **    

200. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP006990 (Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

201. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP013600 (Rhizobium sp. N741 plasmid pRspN741e, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

202. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP013504 (Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

203. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP013510 (Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

204. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP013521 (Rhizobium sp. N113 plasmid pRspN113d, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

205. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP021127 (Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

206. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP013494 (Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

207. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP013594 (Rhizobium sp. N871 plasmid pRspN871d, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

208. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

209. spacer 18.1|4391498|32|NZ_CP040695|CRISPRCasFinder matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 8, identity: 0.75

acgcttcctgcatgaagcttcacgacaggagc	CRISPR spacer
gctgttccagcatgaagcttcgcgacatgcgg	Protospacer
.*  **** ************.***** * * 

210. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_LR134457 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 15, complete sequence) position: , mismatch: 9, identity: 0.71

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
gactggtccgcgccggccaggtgcaggcgat	Protospacer
  ..**** *********.********. * 

211. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to CP000663 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence) position: , mismatch: 9, identity: 0.71

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tggcggtcagcgccggcctgctgcagacaga	Protospacer
.  *************** * *****.. .*

212. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 9, identity: 0.71

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
agggcggcatcgccggccgggtgcatgtcat	Protospacer
     * ** *************** **** 

213. spacer 14.7|4103230|31|NZ_CP040695|CRISPRCasFinder matches to NZ_CP031752 (Rhodobacter sphaeroides strain EBL0706 plasmid p.A, complete sequence) position: , mismatch: 9, identity: 0.71

cctcggtcagcgccggccgggtgcaggtcaa	CRISPR spacer
tggcggtcagcgccggcctgctgcagacaga	Protospacer
.  *************** * *****.. .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	3864361 : 3923810	41	Bacillus_phage(28.57%)	tail,plate,holin	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP040695|3864361:3923810|DBSCAN-SWA
GTCACCATTCCTCGTCCTGTTCGGAGTTCCACACCTGGCGGTCCGCCACCCAGAGCTCGGCCGTCACGTGGGCCGGGATCTCGTCGCGCACCATGTCGACGAACGCGGCCTCGTCGAGAGAACCGGTCCGCTGGACCCGCATCCGCACCCACGCCGTGTCGTCGGGCACCTCACCCGCCCGCCAGATCCCGCCCCCCTCGACGACCTCGGCGGTGGAGCCGCTGAGGAGCTCGAGGTACGACGTGAGCCCGGCGACCGTGCCCCTCGTGGCGAGGGTGCGAGCCGCGGTGGCCACGATACGGCGCCGCAGCGCCTCCGGCATGGAGTTGTCGAGCTTGTCCACGCCAATCCACGACCCGAGCCAGGCGATCGAGCTCTCCGGCGCGATCGTGAGGTCGACGGCGTGCTCGACGCCGTCGGCGTCCTCGAGCAGCGTGCTGCCGAGCTCCTGGAAGATCGAGACGAACCGGACGAAGAAGTCGTGGCTGAGCATCTGCACCGGCAGCTGGCGCAGCATCCAGTCGTCGGGACGCCGCGGCTTGCGCGGGCGCGTCAGCCCGGCCGAGGAGACCTTGACCAGGGCGCTCATCGCACCACCACCTGGTGGGACGCCGAGAGGAACAGCGACTGGCGGTCGAGCCGGATGACGTCCTTGGCCGCGCCGAGGCGGCGTCCGGTGCGCAGGTCGTACTCGAACAGCAGCGCCTCCTCGACCCGCTCGACGCCCTCGACCGACTCGAGCAGCTGGGTGACGGTGGCGACGTTCAGGTCGGCGTCGAAGGGCCAGCCCGCGCCGTCGGGCCCGCCGATGAGCGGGTTGACGAACCGGGCCAGCGCCTCGGAGGCGCGCTGCTTGACGATGCCCTGGGGCCGCCCGGGGGCGCCGTGGACGAGCGCGACCACCGAGACCCCCTGGTAGAACGGCGTGGTCACCTCCACGGCGGTGCCCACGACGCGGTGGGCGTCGAGGTGGTCGGTGACGGTGGCCATCAGCTGCGCGGAGATGGCGTAGTCGTCGATGGTGTGGCCGCCGGCCTCGCCGCGCACCTCCGGGACGACGAGCAGCTGCACCGTGCCGTTGCCACGCCGGGCCGAGCGGCACCGGGCACGGGCCACCGCGGGCGAGGCCTCGAGGGTGAGCCGCTCGTAGTCCTGGGCGGTGACGGCGCGCTGGCCCGTCCGCAGGGTGAGCGGGCCGCGGACCTTGGCCTCCTCGACGCTCTCCGCGTCGACGCCGCCGGTCGCCGGCAGCAGGTTGACCACGCCGCTGACGAAGGGGACGGTCGAGCGCAGCAGGGTGAGGGTGCGGGCTCCGACGTTGCCGCGCGAGCCGCCGCCGTGGCGGTAGCCGCTGACCTCGATCATCGCGCCGTCGCGGGGGATGTCGCCGTGCTGGCGCACCGACCCGTCGGGGTAGCGCACCCGCGGACCGAACTGGATCTCGCCGTTGCTGTCGTTCCACACGTAGTGCCGGTCACGCGGGGTGGAGCCGGAGAAGTCGGCGACCTCGGTCCACTCCTGCACCTCGCTCCCGTCGACGACGCGGACCACCTCGTCGCCGCGGCGCGGGAGCACCGGACGGTGGGTGACCGAGAAGCGCTGGGCGGCGCCGCCGTCGCTGCGGCCGACCTGCTCGCCGGGAGCCTCCTCGGCGTGCTCGGCGCGCACCGTGCCGCCCAGGGCGGAGACCTCGATGCGCTGCACCCGCGGCGAGGCCTGGTAGGTCGGCCGGCCGTTCGCCGTGGGCAGCAGGCGGGCCCGCAGCCAGTAGGCCGACTGGTTGCCGACGCTCATCGGCTGGTGCTCGACGGGGACCATCAGCACGATCTCGCCGGCCCGGTTCAGCCCGCCCGTGGTGTCCTCGTAGACCTCGGTGGCCAGCCAGCCCTCACCGTTCCAGACCTCCCAGGCGATCGGCGGGTTGCGCGGGTCGACGCCGATGCCCTCGGCCTGGGCCTCGACGGCCAGGCGCAGCACCATGCCGGCGAGCGAGTCGCGGAAACCGAGGCAGAAGGTGTCGCCCACGGCCATCGTGGAGGAGGCGAAGACGCGGGCGCCGACGGTGCCGAAGCGGAGGTCGTCCCACACGTCGGTGACCGTCCCCTCGACGGCGGTCGACACCTTGGCGTGCTCGAGCCGCGGCGGCGCGATGACCAGCTCGGCGACGGTCGAGAAGACCACCGAGTCGACCGCGGCCGACGTGGTCGACACCGTCATCACCTCGGTGCTGGCGGGCACCACGACCGCGGACTCCAGCACGGCGGAGAGCCAGAACGTGAGGTTCGTGCCGGCCACCGACGGCGGGAACGGCTCGATCCCCACCATGTTGAGGAAGTGCGTGTAGAGCCGGTCGGGCACCTGGTTGACGCGGTAGAGCACCATCTCGCTCATCCACGCGAACAGCTCGATGAGCGCGACACCGGGGTCGGAGACGTTGTGGTTGGTCCACTCCGGGCAGAAGCGGGGGATCATCCGCTTGGCCTCGTCGACGATGTCCTGGAAGGTGCGGTCGTCGAGGGACGGGCTCGGCAGGGGCATGGCTTCGGGTGTCCTGACTGGGCTTCGCGACGGCTATTCGGCGTCGTGCGGGATGACGTAGAACGGGTAGACGAGGTTGCGGCGGTCGTTGGTGGAGCGGACGCGGTAGCCGATGTGGATGTTGACCAGCGAGGAGGAGGAGTCGTCGCCGGTGCTGGTGACCTCCTCGACGGTGATCCGCGGCTCCCACTGGGCCAGGGCGTCGCGCACGGCCTGGTTGATGAGACCGAGCAGGTTGGCGGTGACCGGCTCGAAGAGCAGGTCCCAGATCCGGCAGCCGAACTGCGGCCGCATCAGCCGCTCCCCCGGCGCGGTCATCAGCACCATCTCGATCGAGCGGTCCAGCTCGGGGACGCCGCTCGACAGCCGGATCGAGCCGGTGTGGTCGACGCCCATCGGCCAGCCGAAGCCGCGTCCGATGAACGACGTCTCGTCCCCGTGTCCGCCCGGCACCGTCAGCTCGCTCATCAGTTGATCGCCACCATCGCGCCCTTGAGGGTGAGCGGGCCGCTCGCCTCGACCGAGGCCATGCCGTCCGCCTTGACCTTCACCGTCGAGCCCCCGACCTCGGTGCCGGCCGTGCCCTTGACGGCGACCTGGCCGTTGGCGGTGACCTTGATGCCGGCCTTCGCCTTGATCTCGATGTTGTTGCCGTCGAGGGTGATGTCGCCGTTCTTGGCCAGGACCACCTTGGCCTGGCCGTTCGACAACGTGATCGGCAGCCCGTCGGAGATCACCTCGACCTCCTCACCGGAGATCTTGATCTGGTGCTTCTTCTCCTGGTGCTGCAGCAGGATGTGCTGCTCGCCGGGCTGCTCGCCGTCGGCGAGCTCGACCATGTGACCGAGCCGCGAGGTGATCCGGCGGTACTTGATCTTGTTGTTGGCCACGGCCGTGCCGCTGCCGACCGGCAGGGTGTTCTTGGCCGAGAAGAGCCCGCCGAGGACGACGGGCCGGCGGGTGTCGCCGTTCTCGAAGGCGATCAGCACCTCGTCGCCGACCTCTGGGTAGAAGAGCATCCCGCGGTCCTTGCCGGCGCCGAGGACGACCATCCGCGCCCAGGCCGACTCGACCTCCTCGGAGACGGCGGAGTACTTGACGGCGATCCGGCCCTTGTTGTCGGGGTCCTTGAGGTTCGTGACGAGCGCGGCCAGGACGCCGGACACGGCCATCCCCGAGTCGGGCGGCGGGGTCCCGAGCAGGTCGACGAGGCCGGCGGGGCGGACCGGCCCGGCGGTGAAGTGGGTCCGGAACCCCGCGCTGTGGCTGTAGACGTGCTCGAGGCCGGTGACGAGGTAGGAGCCGGACGCCGGGCCGGCATTCGCGATCTTGACCTTGTCGTAGAGCTTGATCCGGGAGTTGATCGCGCCGCCGCCCTTGGCGACGACCGCCGCGGAGCTCGCCTCGGCGAACCGGGCCCTGGCCATCGTGCCGGCCTCGCCGGCGTCGAGCGCCGGTGCCGCCAGGATGACGTCGGTGGCGCCCCGCGAGGGGCGGGTGGCGCGGCCGGCCGCCTTGGCGACGAAGGCGGACTCCCCGGTGACGCTCGTGGTGTGCTCGCCGCTGACGACCGCCTGCTGGTCGGGGTTCCAGCCGCGCACGACGACCTGCGCCGGGCCGGTGTTGGTGGCGCGCACCGAGAACGACGTGAGGTCGTCGGTGCCGAGCGCCAGCGGCACCGTCGCGCCCGCGGTCCCGACCGGGACGACGTTCAGGGCGACCCCCTCGACCCACCAGGCGAGCCCGGCGCGGGAGCAGATGGCGTTCAGGAAGGCCAGGTTGCTGCCGGCCTGGAGCTGGTAGGCGTGCGCCGGGCTGGTCGCGCCCACGCTGCCGACCGAGAGGCCCGACTCGCCGATGATCTTGCGGACCACGTCGGAGTAGGTCTGGTTCAGGAAGGTGCGGTTCTTCGTCGAGCCGTTGAGCCGGCACGCCTTGTCGTCGACGGTGACCACGAGCACGGGCGTCTGACCGGCCCCCTGCTCCAGGACGACGCCGGTCACCTCCCCGATCATCAGCTGGTTGCCCCCGGCGGTGACCTCCACCTCCACGCCCATCGCGAACTCCTGGGACGTCGACAGCGCGAACCCGCGGTCCCGGAAGCGCAGCACGGTGCGGCCGGACAGGCCGATCGCGAGGTCGATCCGGACGCTCGCGAGCAGGTCGAGCCACTGGGAGCGCAGGGCGGCGCCGCCCACCGTGACGGTCGGCGCGATCCCGAGCTCGGCCATCAGTTCTCCAGCCGCGGGATGTCCAGGATGGTGCCCGGGCGGACCGCGAGCGGGTCCTGCAGCCCGTTGGCGTCGGCGAGCATCCGCCACCGGGTGGCGTTGCCGTAGTAGCGCGCGCTGATCCGGTCGAGCGTCTCGCCGGGCAGCACCCGGTGGGTGCGGTGCGGCTTCGGGGTGCCGGACGTCGGGTTCTGCGGCCCGAACGCGTGCGACTCCTCGTACTGGCGCAGCTCGAGCAGCATCCTGGCCCGCAGCGGCACGCCCGAGGAGGAGAAGTAGGTGAAGGTCAGCTTGAGGTCCTGCACGACGGCGACGAAGGAGTGCAGGTCGCCCCAGTGGAAGGTCAGCGTCGGCGGGCGCACGTTGTTGGACGTCTCGTCGCTGCCGGGCAGGTTCGGGTCGACGTCCATCAGGCCGAGGATCTTGCCGGTGTGGACGCTGACCGGGGTGCCGTCGGACGTCGTGTCGAAGACCAGGTCCAGACGCATCCACCCGGACGTCGCGCCGGCGTACTGCAGCGTCGGGACGCCCTTGCCCGGCATCGGGTTGGAGGTCCAGTTGTTGCGCCGGCCGACGCTGAGGGTCTCGGGGTTGTACAGGCACGGCACCTTCGCGCCGCCCTCGATCTCGAGGAACGCCTTCTCCAGCTCTGCCATCAGAACACTCCCCAGTCCTGGCGCCGTCCGCGCCGTTCGAGCTCGTCGACCACGCGGGCCTCGATCCGCTCGACGACGGCGTCGACGAGCGCGTCCATCGCGTCACCGGGCAGGTTCCCGGCGTCGGCGTCGGCGGTGTTGACCGCGAAGCCGCGGTAGCCGTCGTTCGACGTCCACCCCGTCATGTCCTCGGCGGGCTGGATGCTGCCTCCGCGGTGCTCGAGCTCCCAGCTCTCGCGACCCTGGCCGAAGAAGTCTGGTGCGCTGCCACTGGGCATGGCGGGTCCTCCCTGGTCGAGCAGGCGCCGGACGACGCCGGCCTGGGCGTCACCGAACAGGTGGGCGGTCGAGGAGAGCAGCGAGCCGCCGGCCGGCGGTGCCGCGGGCGAGGCGGGGGTGGCCGGCGTCGTGGTGCTCGAGCGGCGGACCACGTCGGCCCGGGCGGAGGCCGGCACCGGGGGCGCGCCGGCAGCCGCCGGCCGCGACGGCTGATGCTGACCCGGGGCGGGGCGACGGTCATCCGGCGCAGCAGGCTCGGGTCGGGCCCGGCGACAGCCGGTCCGCCCGGCGTCGCTGGGGTGCCGGCGCGGCCGAGGCGGGCCACGGCGGGGGCCGCCGGTCCGGTCGGACCTCCCGGGCCGAGCGGCGGCCCACCCGAGCGGGCCACGAGCGCGACCGCCTCGGCGGTGCCGGCCGCCGGGTGGCGACCGAGCGCGGGGACCTGGGCGCCGGGGCCGGAGCGGCGTACGACGGACGCCGAGTCGCTCGACGCGGGGTCAGGGACCGGCGGCGCAGCCCACCGCAGCACGGTGGACGCCGCGGACGTGGTGCCGGGCGCGGAGCCGCCCGTGGTGCCGGGCGTGGTGCGGACCGCGGAGCCGCGGCTGCGGACCGACGCCGCGGACGGCGCGGAGGCCCGGGCGACGTGGCGACGGATCGACTCCGGGGCCGACGCGGCGCGACCGGCCCGGCCCGCACGACCACCGGCGGCGCCGACCAGGCGGGGGTCCGGGAGCGAGGCGCTCGCGGTGGCGGGCCGGATGTCCTCGGCGGTGCCCAGCGCGGTCGCCAGCGGGTGGCCGGCGTCGACGCCGTGCCGGGTGGAGCGGCGCACCGAGTAGAGGTCGCCCATCGCGACCGACGTCGCGCCGACGCGGCCGATCGACGCGGCGATGGTCGGCGCGGTCACGGGGACGGCGGCCGGCGCCGCCGGGGCGGGGGCGGCAGCCGCGGGGACGACCTCGGCGGGCGTGCCGGCGGGCGTGCCGCCCTGGGTGGCCGGGGTGGGGACGGCGGCGTCGACGCTGCGGCGGACCACGGTCGCCGACCCGGCGGAGAAGCCCGCGTCCGCTGCCGTGACGCCCGCGACCACCGGGGCCTGCCGGCCCACCACGGCCGAGCGGCGCACGTCGGCGGCGGGGGCGATGACCTGGTCGGTGCTCCACAGACGGCGGACCGGGCGGCGGGTGCTGCGCGCGAGTCCGGGGGCGGCGGCCGAGGCGGCGAGCCCCGGCGCGGTCTGGATCGGGGCGATCGGCGGCGGGGCCGACCCGCTCGGGTCGCCGGCGGCCGGGGCGGGACCCGAGGCGGCCGCGGCCTGGGCAGCAGGGGTCGCAGGAGTCGCAGGGGTCGCCCCGAGCATCCGGCGCAGGACGCCGCCGGGGCTCCGGCCGACAGCCACGGTGGATGTGGTCGGAACGGCGGCGGGTGCCGCCGGAACGGCGGCGGCAGGCCGGCCGTGCTGCTGGGCTCCGGGGGACGCGGGCGCGGGGGGTGCCGTCGTCGAGGACCCGGCGGCCGGCGCCACTGCCGGGGCCACCGCGGGTGAGGCGGTGGCGCGGACCTGCGACGGGGCGGGTGACGAGGAGGGCGAGGCGACGGGTGCGACGTCGGCCGAGGCGATAGACGCCGGGGACGACGCCGCGGTCGCCGTCGAACGACGGACCGTGCCGCCGGCCTGGCGCATCACCGGGCTGGACGCCGTCCAGCGCTCCCGGCGCGCGGCAGCGGCTCCGGCAGCGGCACCGGCACCGGTGGCCGGGGCGGCGTGGGAGCGGGCGATGAGGCCGGGGCCTGCGGCGCGCACGGCGTCGCCGTCGCGGACCGCGCTGTCGAGTCCTCGCTGCTGGGCCGAGGGCAACGCGGTCGCCGCGGCGACGGGCACACCGCCGCTCCCGGTCGTGCTGCCCGGGACCGTTGCCGCGGACGCGGCCGGAGCCGGAGCCAGGGGCGTGGTCCCGGCCGAGGTCGGGCGGCTGGGCGTCGACGCCGCGGCCAGCCCGGGCGCGGTCGAGCGCGAGCGCGCTCCCGCGCTGCTCAGCGCCATGCCGGCCGAGCGGCCGGACTGCCGCATCACCAGGCTGCCGGCCGACCACACGTCGCGGCGGGAGACGCCGGGCGGGGTGGCCGAGCGACGGATCAGGGACGGCGCCGACGCGGCGAGCGTCCGGGCGTCGCGGACGCCGCTGTCGAGCGCGGCGCGGCCGGCGGCCAGCGGCGCCGAGGCGGCCGTGTGCGTGGCGGCGGTGGCCGGGGTGCGGCGGACCATCGTCCCGAACCGGCCGGGTCCGGAGCCGAGCTGCCACGACGCGCGGCGGACGGGGCCGGCCGCCGAGGAGGGCGCCGCGGAGGCAGAGGACGAGGAGACAGGGGACGAGGCGGACGACGCGGGGGTCGACACCGCCGCCCCGGACGGACCGCTGACCGGGGCGGACGGCGGGCTCGGCGTGCCGGGCCCGGAGCCACCGGAGGAGCCACCGGACGGGCCCGCGGGCGGACCGCCGGACGGGCCGGCGGACGGGCCGGGGGGTGCCGCGGGACCGTCACCGGGGTCGGGACCGTCGGCGCGGGGCGGGCTGGTGGGGGTGGCGCTCGCGGCGGCGGTGGACGGCGTCCGCCGCACCGGGGGCGCCGGGTCCGGCGGGGGCGCGACGACGCGGCGGGTGGCCTGGAGCCGGGAGAGGTCACCGGGGGTGAGCATCGGACCGGCCGCCTGGACCTCGACGTGCCGGCGCACCTGGGCGACCTGGGCGGTCAGGCCGCCGACGATGCCGCCGGGCGTGTAGGTGTCCTCCTGGGGCACCGAGCGCGCCGCGCGGGGCAGCCGGCGCTCGGGCAGCGCCTCCACCTCGAGCGGCCGTGACGGGCTGAGCCAGGCGGGCCCGGGGGCCGGAGGTCTCGACTCGGCTCGCTGGCGCTCGCCGGCTCGACCAGCGGAGGCGGGGGCCGGCGCACTCGACTCGGCTCGCTGGCGCTCGCCGGCTCGACCAGCGGAGGCAGCTCCCGCTGTTCTCGACTCGGCCCGACCGACAGGGGCAGCTCCCGCTGGTCGAGCCGCGGGGACGGAGTCACCGCGTGTCGAGACCACCGGAGGCCCGGTCTGACGAAAGACGGGGCGGGGGTCGACGGCGTCCGCGGCGTCCGCGACGTCGTCGGCCGGGCGCGGTACCCACCAGCGCGGCGGACGGACGCCGGGGCCGCCGGGGTCGGGGCCGGCCAGCGCGCGCCGGATGTCGATCGGGCGCGAGGTGGCGGCGGCGAAGCGGGAGACCCCGGAGGCCAGCGACCCGATCCGGGACGGCAACGGGCGCCCGACCGGCGGACCGGGCAGGCGCAGACGACGGCGCACGGCACCGCCCAGCCACGGCGTGGTCGGGGGCGGGGAGTCGGCGGGGGCCGCCGGTGCGTCGGTCATGTCGGTCATCTCGGGGGGTCCGGGGTCAGGCCTGGGTCTTGGCGCGGAACCCGTGGTGGGCGATCTCGAGCTCTTCCTCGAGGGCGTCCTGGCTGGCGACGGAGAAGTCGGGTCCCTTCCACCGTACGGGGAAGACGTCGATCAGCTCCCAGGCGCGCAGCCGGGTGCCGACGTGGTCGATGGCGGTGACGGCGCCGGTCGAGCGGGTCAGCTTGTTGCCCGAGCTGGCGAACCCCTCGCCCGAGCTCTTCTGGAGCCACTCGAAGAGCGCGTTGCTGGAGGTGACGCCGCGCTTGAAAACGATGTTCGGCCAGGTCATCCGGCCGGGCACGCGGTGGCTGAAGCCGTTCTGCCCGCCCTCGCGGAACTCCTCGACGCCGACGGTGACCTGAAGCCCGTAGAGCTCGCGGAAGACGCCGATCTCGACGCCGTCCAGCTCGAACAGGAACCGGTTCGCGGTGGGGATGTCCCCGCCGAGGGGATCCTCGGCGGGGCTGCCGGTTCCGCCGCTACTGGCCATACTCACGCACCACCTGCCAGGCTCGTTCGTTCAGGGAGACGACCGCGCGCACCATCCGCACGCGGTCCATGTGCTCAAGGTCGAGCAGCTCGTCGAGCGGCCAGTGCAGGTGGTAGGCCAGGTAGGCGATCTCCTGCCACAGGGCATCACTCGGGTAGCGCATCATGCGGCGGTGCTCCTGTCCCGACGCACGCTACGACGAGCGACGCGGCAGCTCCTCGACGCTGTGCCGCAGGCTGGGTCGCTCCGACACCTGCTCCGAGACACCCGTCGGTCCGGCCGGGGCCGGAGGAGCGGTCGCGTCGTCCGCGGACCCCGGCCCGGCACCCTCGGCGGCCGGAGCCGCCGCGGGGGCCGAGGACGGGGCGGGTGCGGACGACCCGACCAGCGCACTGGACTCCTGCGCCGCGATCAGGGCGTCGAACTCCTCCTGGTTCCCGAAGTTGATCACTCCGTAGAAGTCCTGGAGGAACGCGAGGTCGACCGCGAACAGGCCCTCGATGACGTACGAGTTGATCTGCTCGAGCGAGCCGAGGCGGGTGACCACCCTGGTGAGCACCAGGATGGTCAGCCTCGGGTCGTCGGGACCCTGGACCGTGGGGTCCCGCAGCGGCGCGAGCTCGTCGCGCGCCGTCGCGAGCCGCATGACGCCCTTGCGGTGCAGGGTGCCCTCGTCGTCCACGTAGCCTCGCGGCAGCGTGAACTCGTACGTCGTGCGCAGTGAGCTCACTTGACGCGGTCGAGCCGCTCGATCACGAGGGTGATGGTCTCCTTGACCGCCTCGTTGGAGTCGGTGCTCACGGCGTCCGTGGCGATCTTGCTGGGCCAGCCCTTGGAGAAGTTGAAGCGGCCGACCTCGGCGTAGGCGCCGTCGTAGAGCACGATCGAGCCGTCCTTGCGGGTCGCGGTGCGGGCGGTGCCGCCCATGCCCTTGTCCCGGATGTCCTTGAACCACTTCCAGATCGGGTCCGACATGGCATCCATGGGGGCCATCCGGGTGATCGTGATGTCGGCGGCCTTGTTGATGTTGCCGCGGGTCTTGACCATCTCCGAGCGGCCGGTCTTGCCGACCTGCTGGATGGAGACGACGTCGGCCTCGACGTCGAGGCCGGAGACGCCGGTGAGGATGATGTTCTCGCCGGCGATCTCCAGGTAGAAGTTCTGCGCGACGATCGGGTCGGTCGCGATGAGAGACTCGTTGGGCATCTGCTAAACCACTTTCTCGGTGTGGGTGAGGGGGACGGTCTCCGGCGTCAGCCGGCGACCTGCTTCTTCTGGCTGATGCGGAACACGACGAACTCGGCGGGCTTGACCGGCGCGATGCCGACCTCGACCACGAGCATGCCGGCGTCCACGGACTCCGGCGGGTTCGTCTCCGCGTCGCACTTGACGTAGAACGCCTCGTCGGCCGAGAGACCCGACAGGGCGCCGGCGGTCCACAGACCACGCAGGAAGCCGCTGACGGTGCGGTTCACACCCTCCCAGAGCGCCATGTCGTTCGGCTCGAAGACGGCGTACTGGGTGCCCTCGAGGATGGTCGACTCGACCATGTTGAACAGGCGGCGGACGTTGATGTAGTTCCAGTCGGTGTCCGAGGCCAGGGTGCGCGCGCCCCAGATGCGGATGCCGCGGGTGCCGAACGGGCGGATGCAGTTGACGCCGATCGGGTTGAGCAGCGACTGCTCGTTCTGGGTCACCGAGCGCTCGATGTCGAGGACGCCGCGCATGGTGTCGTTGGCCGGGGCCTTCCACACGCCGCGGGTGTCGTCGGTGCGGGCCCAGACGCCGGCCACGTGGCCCGACGGGGGGATGAGGATCTCGGTCTCGCCGTTGGTCGGGTTCGGGTTCTCGACCTTGACCCAGGGGTAGTACAGCGCGGCGTAGGCCGAGTCGTACATGGCCGTCTCCGAGCGCCACTCCTTGACCTGCTGCGGGTTCATGCCGGGAGGCGCGTCGAGGACCGCCATCCGGTTGCCGTTCTGCTCGCAGTGCGAGATCAGGGCGGTCTGGACGGCCTTCCACAGACCGAGGTCGAGGCTGCCGTCCTCCTTGGTGGCCGCGGTGACGAGGTCGGGGACGATCACCATGGTGACGTCCTCGGCGACCGCGAGACCGTTGATGCCGGCGCGGGCCGACTCCGAGCCGGCGAACTTCTTGCCGGTGACGGGCACCGGGATCGGCGCGGCCTTCGAGAGGCTGTAGGTGCCGGGCTTGACCAGCTCGAGCTGGCTGGCGACGTCGGCGTCCTCGGCAAGGTCGAGGTCGACCTTGACCTTGGTCGAGGTCGCGTTGACCTTGGTGGCGACGTTCGAGTCGCCCTTGTCGAAGCTGAGGCCGGAGAACTCCTCGACCGCGACGCCGTTCTCGATGATCGTCATCGTGAAGGTCGGCTGCGCGTCGTCGTCGTCACCGGCGTCGTCCGAGGTGACCTGGACGGCGATGTTGGCGTCGGGCTCGACGCTGGTGACCGCGACGGGCAGGCCGAGGGAGCGGTCGGCGGCCGGGAGGGCGGCCGTGGCCGGCTCGCCGGCGGGCTCGGTGTTCGGCACGCGGCAGATGTAGGCGATCGAGCCGCCGTTGGCGAAGTAGCCGTAGACGGAGAGGGGGAGCATGCAGCCGGGCGCGAAGCCGCCGTACAGGCTCTCGAACTGGGTCCAGCTCGTGACCAGGCGCGGGGCCAGGCCCTGCGGGTCGTTGGGGTCGTCGGTCGGCGCCAGCTCCGTGAAGCCGACGAACGCGGCGACGGCGGTGGGGGCAGCCGAGAGGATCTTCTGAGAGGACGGGACCTCTTCGACGTACACACCGGGTGCGGTGTAGGTAGGCATGGGTTCTCCGCTTCGTGGCTTCGGGGCTTGGTGATTTCGTGGGATCCGGGAGGGCGACGGCATCACGCCCTGGCAGACACGTTCTGACAAGTCGAATCGTGGTCCGGTCGGGCGAGCCCCGGCGGGTAATGGCGGAAAGTGGTTCGATCTGACCAGGGTGCGTCCCAACCGGTCTTGACGTTTTCGCCCGCCGGAGCGCGTTCCCGCCCAGACTGGGGTCGTGACCGCCACCGCCGGGTCCTGGGGCCCGGCCGACCTCCCCGCGATCTCCCCCGCCCGCGCCGAGCGCTACGCGCTGCGTCCCGGGGAGGTGCCGCAGCTGTCGGCGTACGCCGCGGCGTCGAGCGCGCTCGGCCTGCGGGCGCGGATCGTGCTGCTCTCGGGCCGCGGGATCGGACCGACCCAGGTGGCGCGGGTGCTGGGCGTGAGCCGGCAGACAGTGCACACGTGGCGCACGCGCTACGCCGACGCCGGTCTCGCCGGACTCCACGACCAGCCGCCCAAGCCGGTCCGCGCGGCCGACGACCGCGCGATCGTGGCGGCCACCCTGGCGCCGCCGCCGGCGTCGGTCGGCGCCACGACCTGGTCGGCGCGCAGCCTCGCGGCGCACCTCGGCGTCGGGCACAGCACCGTCGCGCGGGCGTGGGAGGCCCAGGGCGTCCGGCCCAACGGCGCCGACACCTTCCGCGTCGCGACCACGCCCGAGCTCGTCGTCCAGCTGGTCGAGGTGGTCGGGCTGGTCCTGGCCCGCGACGTCCGCCTGGTCGCGCTCCTCGTGCGCGACGCCACCGCCACCGGGGCGACCCGCCACGCCCGGACCCGCTCGCCGCGCACCGGCCTGGCCCCCCTCTACCTGTACGCCGCCACCCGCGCCGCGCTGGCCGACCCCGCCGCGCACGCGCGCCGCGGCCGGCTCGACCTCGGTCGCTGGCTCGACGGCCTGGAGGGCAGCGGCACCGACGGCGCGCGGCTGTGCCTGGTCGCCGACACCGGCGACGTCCTCGCCCGCCCCGCGCTCGCGGCCTGGCTCTCGGCCCGGCCACACGTCCGCACCCACCACGCCGGCAGCACCCGCCGGTGGCTCCGCCTCACCACGGCCTTCCTGACCCTCGCCGAGTCCCGGACCACCGGTCCGGGCTGCGCACCCGAGATGGCCGGGCTCCTGCGCGGCCTGACCTCGGGCGACCTCGTCCTGCCCGCCCCCCTGGTGTGGTCCGGACCCGGGGCCCGGGTGCCGGTCCCGGCCCCACCCCGCCGCTAGCCGACCCGGTCGAGCCGGAGGCTCCCCGAGGGCTGCCGGACCGGCCCGCCCGCCGTCCACAGATGTTCGAACACCGTAGCGATTGTCTGCTGGCCGGACTAGAATGGGGCCATGCCCGCAGCCACCGCCCGGACCGCCGACCCGGCGCTGGCGGCGGTGCGCACCCACCAGGCTGCGGCCCGCCGGGCCGAGATCGCGACCCTGGTCGCGGTCCTCGACTGGGCCACCGAGCACACCACCGACGCCGACCCCGCGGCGATGACCTTCGGCGAACGTGCCCTCACCCTCGGCGGCCCCGGCTGCCCGGCGATCGAGGAGTTCGCCGCCTACGACCTCGCCGCCGCCCTCGGCTCCTCCACCGAGTCCGGGCTGAAGTACCTCGCCCGCGCCCTCGAGCTGCACCACCGACTCCCCCGACTCTGGGCCGCAGTCCTCGCCGGACGGCTGCCGGTGTGGAAGGCCGCCAAGATCGCCGACGCCACCATGCGACTCCCCCTCGACGGCGCCACCCACGTCGACGCCCGGCTCGCCCAGGCCGTCTCCACCATCACCTACGCCCAGCTCGACCGCCTCGTCGACGAAGCCATCGCCCGCCACGCCCCCGACCAGGCCACCGCAGGCAGGGACCAGCGGCACGTGCGGGTCGACCTCGACCACGCCACCATCGACGGTCACGTCCGCCTCGACGCCCTCCTGACGGTCCCCGACGCCCTCGACCTCGAACACGCCCTCCAGACCAGCGCCCAAGCCCTCGCCGACGCCGGCTGCGACCAGTTCCTCGACGTCCGCCGCTCGATCGCCCTCGGCGACCTCGCCCGCGGCGACCAACCCCTCGACCTGGCGGGACGCACGCTCGTCGTGCACCTGCACCAGGACTCACCCGACGTCGGGCGCTGCGAGACCACCCGCACCCCGGTCACCGTGGAGACCATCGAGACCTGGTGCGCCACCGCCGCGAAGGTCGTCATCAAGCCCGTCATCGACCTCGAGCAGCACGTCCACGTCGAGGCCTACGAAGCCCCCGACCGCTTGCGCGAACACGTCGAGCTGCGCGACCTCACCTGCGTCTTCCCCCACTGCCGACGCCCCGCCACCCGCTGCGACCTCGACCACGTCGTCCCGTACTCAGCCGGCGGCACCACCAGCAGCGACAACCTCGCACCCCTCTGCCGACGACACCACCGCGCCAAGACCCACAGCCACTGGACCTACCGGATGACCGACCCCGGCACCTACCACTGGACCGCACCCTCCGGCCTCACCTACCGACGAGACCACCACGGCACCACCCCACTCGACCCACCACCAGCCGAGCCGGCCGAGCCCTGACCACCCCGCCCCGCACCCCGCCCACGGCGGGGCCCACCGGCGCGCGGTCAGGTCGTGAGGAGTCGGGACAGAGGACCGTCAGCCCATCGACGTGCGGACGGCGCCGGGCATCGTGATGCTGATGACGCCGCCCCACGCGCAGGTGCACATCGAGCCGGCCGTGACGGCGGGCAGCCCGCCGACGAGCGTCCTCGGGGCGCCGGGCGCCCAGGGCGCCGGGACGACCGGGACGCAGGGCATGGGGGTGAGCACGCCGAGCGCGGCGGCGGTGGCGGCGGCCACCATCGGGTTGGTGAGGCTGGTGCACATCCCGAACGGCGCGATGTTCACCCCGGGCGCGATGTCGGGGATGGTCGCGACCGGGCGGCCCTCGACGGTCACCCGCTTGGCGGGGATCACGTTCAGGGTCGACGGCGCGACGCCGAAGGTGCAGGTCAGCATCGCGCCGGTCACCGCTGCGGGGTTGCCCATGGCTGTCTCCTGGTCACGTCGGTCAGAGCCCGGTGCCCTTGACCGACTCGTCGAGCTGGCGCCCGGCCTCCATGACCAGGCAGACGACGGCACGGTCGCCGGACTGCCAGGAGCGCGGGGACGGGTAGAGGTAGGTGAAGTAGAAGCGGGAGTCGAGGTAGTCGACGCCGACGTAGCCCTTGAACTCCTCGGCGCAGCGGCCGTCGGCGAACGCCGTGAGGGCGTCGTCGCCCGGGAAGACGTCGCCGTCGACGTCCTGGTCGGCCGGCTCGTAGTCGGCGACCGCGTAGGCCTCCTGGTCGTGCGGCTCGTCGCACGCCACGGTGGAGATGTCGCTGATCTGGGCCTTGATCTCCTCGGGAGCGTTCACGCAGTCGCCCACCTCGAGGTCGAGGACCGGGTTCTCGTCGCCGTCGTCGTCATCGCCGCAGCCGGCGAGCGCCAGCACCGCGAGGCACACCGGCACGACGAGCCGCGCGAACCGGCGGGTGTGGGGAGCGTTCACGTTCCCGGTCACGACCTCTCGCTCTCGACGGCCCGGCCCCGGCAATCTAGTCGCGGCCCGGTGCCCGTCGCGGGCGAATGCGGAGATTGCCCGCACGCACCCCGTCGGCGCGCCTACATTGGCCCCGACCCCCCACCCGAGGAGAGCGCACGTGTTCATCAGGTACGTCGACGAGGGCCTCGAGCAGCTGGTCCGCCGTCGCCTCCCGCTCCCCGAGGACGTCGGCGACGTCAGCTTCGACACCCCCACCTCGACCTGGGCCGCCCAGCTGTCCCGACTCACGGTGAACCTCTTCCTCTACGGCCTCGACCGCAGCAGCCAGCCCACCCGCACTGCGCAGGCGCGCGTCGACGCGTCGGGCCGCGCCGAGCGCCGCGCCCCCCTGCCGATGGTCGAGCTCGACTACCTCGTCAGCGCCTGGGCCGGCAGCCCCCGCGACGAGCACCAGCTGCTCAGCGACGTCGTCAGCCTCTTCGCCGGCGTGCCGGTGCTCCCGCTGGACCTCACGCACGCCAACCTGAACTCGACCGTCACCCTCGGCTTCGGCAGCGACCCCACGATGCGACCCCGCGAGATCTGGCAGGGCGTGAGCGGACAGCTCAAGGCCTGCGCCGTCATCCGGGCCACCGTCGCCGCCGACACGTGGGACTGGGAGGACCAGGCCGCCGCCGTCGAGCGCGTGTCGGTGCTGGCCGCGCCGAAGCAGATCTGACACGGTCCGACCCGTCGGGTCGTCGTCGCCCCGGCGGGTGCACCGCGTGCGGATGGGGAGAGAAGTTTCCTCATTCTGCCTCGCGGCGCTGCTCCCTGCTCCTACTGTGCCTGGTGTTGCCCCCCTCGTCCTAGGCCCCCGGCAGGTACCCGTGCTCGGCTCCGTCCCCGCCCTCCACTCGCGGCACTCGTGCGTGCCCGCGAGGCGCGCCCGATGAGACTGGTGACCGAGCACCTCGTCCTGCAGGCCGACCCCGGCACGACCATCGAGATCCCGGTCGACGTCGTCAACACCAGCGACCTCATCGACGGCGTCACCGCCCGCCTCATCGGCCTCCCGGACGCCGCGACCCGGATCGAGCCGCAGCTGCTGCCGCTCTTCCCCGGCGCCGAGGGCCGCCTGGTCATGCACGTCGACGTCCCGCCGTCGCTGACCGCGGGCAGCCACCCGGTCACCGTCGAGGTCGTCTCCCACGGCAGCGGCGCGCCGACGCAGCACCTCGACCTCGACCTGTCCGTGGCCGCCCACCCGGCGCTGCGCCTGCACCGCACGCCGCAGCTGATCCGGGCCCGGCGCTCCGGCCGGTTCCTGCTCGACGTGGAGAACACCGGCAACACCGCGCTCGACGTCACCCTGGCGGCGTCCCTGGAGGACGGCCGCAGCACCGCGCGGTTCAGCTCGGAGCGGCTCACCGTCGACCCGGGCACCCGCACCCCGGTCATCCTGGTCGTCAAGGGCCCGCGGATGATCACCGGCGCCGAGATCGACCGCACCGCCGCGATCAACCTCACCGCCAGCCGCGCGCACTCGATCGCGGCCATGGAGGAGACCGAGCAGGACCCCGACCTGGTCGCCGAGACCCGCGTCGTCCTCAAGCAGCGCCCGACGCTGAGCCGCGGGCTGCTCACCGCGCTGATCCTGATGGGGATCATCGCGGTGTGGGCCGCGATCTTCGTGCTCGGCCTCGCGCAGGTCCTCGGCGGCGACCCGGTCACCAAGAAGGTCGCGACGTCGTTCTACCCGGCCGACCGCGTGGAGAACGTCGCCGCGACGACGCCCGAGGGCGCCCTCGACAAGGAGGACGGCCTGGTCGACCCCGAGATCGGCGGCACGATCCAGGGCGTCGTCACCGCCGCGAGCAACCTGCAGCCGGTCGGCCGGATCCTCGTCCAGGCCTGGCGCGACGGCCGCGACGGCCCGGTGCTGGTCAGCTCGGCGGCCACCCAGGCCGACGGCAGCTACCGCCTCGTCGGGCTCTTCCCCACCAGCTACCGGCTGCGCTTCGTCGCGGCCGGCTACGAGCCGGCCTGGTGGAGCGACCGCGGCGCGGTCGGCCGGGGCCGCGCCACCGCCGTCCCCGTGCCCGCGCAGGGTGAGGCCGAGGGCCTGCAGAACATCGTCATCACCGGCCTGGACGCCTCGATCACCGGCGTCGTCGACCAGGGCGCCTCGCTGACGTCGCTGCCGACGACCGTCGTGGCCCGCTCCCTCGACATCCCCGACGCCCCGACGGTGCGCACCACCACCGACGGCGGGGGCACCTACCTGCTCCGGGGCCTCCTGGCCCCCTCGCGCTACGAGCTCAGCTTCACCACCGAGGGCTACGAGGTGAAGACGACGACCACCTCCGTCGCCGGCGGCGAGAAGCGGCTGCAGCCGAGCGTCGTCCCGGCCTCCGCCGACGGCCGGATCACCGGGCGGGTCGAGCTGCCCGACGGCACCCCGGCCGGCGGCGTCACCGTGACCACCACCGTCGAGGGCGAGACGGTCGCGGTCGTCACCCCGACCGTCGGGGCGGTCGGCTCGTTCACCCTCGAGAACCTCCCCACCCCGGCGACCTACGTGCTGACCTTCACCTCCGAGACCTACGGCGCCGACACCACCATCGTCGACCTGGACGCCGGCGCCAGCGAGGACGGCGTGGTGGTGCAGGTCGAGGCCGGCACCACCAGCGTCACCGGCTACCTGCGCGGTCCCGACGGCAACGGCCTCGGCGGCGCGACCGTCACGGTCGGCGGCGTCGCCGCGACCGAGGACGGCACCACGACCCCCACCACGACCACGCTGACCTCCGGCGACGTCGGCCGGTTCAGCCTCAGCGGCCTCGCGGCCCCCGGCGACTACACGCTCACCTTCACCCTCGAGGGCTACGCCCCGCGCAGCGTCCCGGTCTCCCTCGACGGCGTCAGCCCGCCGCCGGTGGTCGAGGTGCAGCTGAACAACAAGCTCGGCGGCATCGCCGGCCAGGTCTACGGCGCCACCGACAACCCCTACGTCGGCGCACAGGTCACCATCACCAACGGCCTCACCACGTGGACCGCGACCAGCGGCGGCGCCGGCAGCATCGACGGCAACGGCGGGTACCGGGTCGAGGGTCTGCCCTCGGGCACCTACAGCGTGACCGTGACCGCCGAGGGGCTGCGCCAGCAGACCGCGATGGTCGTGGTCATGGAGGGGCTGACGTCCTTCCAGGACCTCGCCCTCGGCTCGGGCGGCGGCTGAGGTGCACGTCGACGTCTCCCCCCGTCAGTTCGACGTGATCGCGGGCATCCCCCAGCCGATCGTCGTCACGCTGAGCAACACCGGCGACGTCATCGGCGGCTACACGCTCCGGGTGCTCGGCGCCGACCCCTCCTGGGTCGGCATGGACGACGCCGAGATCACCCTGTTCCCCGACGAGACCCGCACGGTCGTGGTGACCCTGGAGGTCCCGCCCGGCATGACCGCCGGCGACCGCCGGGTCGCCCTGCAGGTCCGCGAGGTCACGCCGCCGTTCGCCAGCATCGTCGAGGACGTCGTGCTCTCGGTTCCCGAGGCGCCCTCGGTCACCGTCACCGCCGACCCGGTGGTCGTCTCGGCCGGGCGCACCGCCAAGCTCAGCATCCTGGTCGCCAACGAGGGCAACACCCGCGTCAGCGGCCGGATGCACGGCCAGGACCCCGAGGGCCGCGTCCGGTTCGAGTTCAGCCCGGGGACCGTCGACCTCGCGCCCGGCGAGAACACCATGATCGACCTGCGCGCGCGCAGCCGTCGTCCGCTGACCGGCAGCCCCGTGATCCGCCCGCTCGAGCTGCGGATGCTCGACGAGGCCCAGAGCAGCGCCCTCGACCGCGCCCAGGAGGAGCCGGTCGCCGCCGGCGTCGCCGCGGACGCCGGCGAGCCCGCCCCGCGACCCAGCGCGGCCCAGAAGCTGAGCCCCAAGCTGCGGCGCAAGCGCCCGCCCCTGGTCGGCGACGACGTGCCGGCGCAGGCCCAGGCGACGTTCGTGCAGCGCGCGACCATCTCCCGCGGCGGGCTGTCCCTGGTCGGGCTGCTCGTCGCGGTCACCGTGTTCGCCATCGTCATCACCCTCTCCCTCGGCCAGCTCGTCGGGCGCTCCGCCGAGGACCGCGACCTCGCCCTCGCGATCGCCGCCGCGGGCGACGCGAGCGCGACCGGCGGCTCCGCCCAGGTCGGCGGCACCGTCCGGCTGCTGACGTCGAGCGAGCCGGTCGAGGGCGTCGAGGTCAGCGTCTTCGCCGCCGACGACACCGAGAGCGCGCGCGGCACCATCGCCACCGACCGCAACGGCGCCTGGAAGGTCGCCGACCTCCCCGCCGGCGACTACAAGTTCTCCTTCCGCGGCGCCGGCTTCGTGCAGCTCTGGTACCCGACGGCGCTCGACGCCGCCGACGGCCAGACGGTGACCGTGGAGTCCGGCGGCCAGCAGCTCTCGCTCGACGTCGACCTCGGCGGCGTCCCGGCCTCGATCAGCGGCACCGTCGTCGGCGCCGACGTCTCCAACGCCACGCTCACCCTCAAGGCGCCCCTCGACGCGACCAACGCCGGGGCGGGGGCCAACGCACCCATCCCGGCCGACGGCGTCGACAACCCCTCGGTCGACGTCGCCTCCGAGGGCGCGACGGTCACCTCGGTGCCGATCGGCGACGACGGCACGTTCTCGCTCACCGACGTCCCCTCCCCCCAGACCTACGACCTGGTCGTGGAGAAGGAGGGCTACGCCACCTCCACCCAGCGCATCGACGTCAGCGCCGGCGAGGAGCGCGAGGACGTCGAGATCACCCTGCGCCAGGGCGACGGCGTCATCAGCGGCACCGTAAGCTCCGCGACCCAGAAGGTCGAGGGCGCCACGATCACCGCCACCGTCGGCCAGACCTCGGTGACCACGACGTCGCAGACCGGCGCCCAGGGCGGCGACTTCACCCTGCGCGGCCTGCCGACCCCGGCCGCGTTCACCCTGGTCGTGAGCCAGGAGGGCTACGCCTCCCAGACCCTCACCGTCGCCCTCGGCGAGGGGCAGCGCCTGACCGGCGTCGCGGTCAACCTCGACAAGTCCTCCGGCGAGCTCTGCGGCAAGGTGATCTCGGTCCTCGACGACCTGCCCGCCCCCGACGTCACGGTCACCGTCACCGACGGCAGCCAGACGGTGCAGACCGCCACCCAGTCCGACGACTCCGCGGGACCGGCCTGCCCGACCGTGCCCGGCACCAACTGGAAGGCCTCCGGCCTCCCGCTGCCCGGCGACTACACGATCACCTTCGCCCGCGCCGACCTCGAGTCGCAGACGGTCGCCGTCGCGCTCGACGGCGAGGGCAACGTGTCGGCCGACGCCGAGAACAGCGCCGTCGTCAACGGCGTCATCACCGTGCGGCTCCAGGCCTCCACCGCCGTCGTCTTCGGCAAGGTGACGCAGTCGCCGACGCGCGGCGTCGCCGCCGAGCCGGCCGGCGAGACCGTCGTCCAGCTGATCTCCAACACCGCCACCTACAGCGTGGTGGCGGCCTCGGTGCCGGCCGCGTCGGCCGGCGACTACCGCTTCGATGCCGTGCCCCCGGGCACGTACACGCTGCAGACCAGCAGGAGCGGCGTCACGCCCACGACGGAGACGCTCACCGTCGAGGCCGGCCAGGAGTACGAGCGCAACCTCAAGCTCGACCCGCCGGCGTCCCTCAGCGGCGTGATCACCAACGCCCGCCCCGGGTGGGTCGTCGAGCTCTACCGCTCCTCTGCGTACCCGAGCCAGACCTACCTCACCACCACCGTGGTGATGAGGGAGATCCGCGGCCGGGGGTGTCCCGAGAACATGTGCGCCTACTACGAGTTCCTCGACATCGACGCTCCGCAGACCTACGTGATCCAGGTCCGACGCACCAGCGGAGGCGCGCCCCTGGCCACCGCCCGGGCCGAGGTCAACCGCAGCGAGCCCCAGACCAAGGACTTCCAGGTGCGTTCCGATGGCTGACCACTCCCCGCACGCCCCGCTCCCGCCGGGAGTCACCACCGCGCCGGTCCTCCGGACGGCGGCCGGCGTCGAGCTCGCGGTGCCGGTGACGGTGACCAACACCGCCGCCGCCCCCCGCGTCCTGACCGTGACCCCGCTCGGCGTCGACCCCGTGTGGGTCGTCGGCCCGCCGCTGCGCACCGCGACCCTCGGGCCCGGTGCCTCGCAGGAGCTCACCGTCGCCCTGCACCCGCCGCAGGGCACGCTGCCGGCGTCCTACCCGCTCGTCGTGACCGTCCAGGCCCTCGACCCCGCGACCGGGCTCACCGACGGCAGCCGGCCCGGTCTCGCCGAGACGACCCTCCTCGTCAACCCGCGCACGACCCTCTCGGTCTCCCTCGAGCCGGCGGAGCCGTCCGCGATCGCCAAGGCCCGCTTCACCGTCGTCGTCCGCAACGGCGGCGGCGTCGCCACCGACGTCGCGCTCAGCGTCACCAACCCCTCGATCGGCTACGTGAAGCTGCGCCGGCAGCTGGTGACCGTGCCCGCCCAGGGCGAGGTCCGCGTCGGCGCGCGGGCCCGGATGAACCGCCCCCGGATGGCCGGCTACGGCTCGCGCGCGGCGTTCGCGGTCACGGCGAGCGCCACCGAGTCCGTGCGGCACACCGTCGGCACCCTGCACCAGCGCGCGCTGATGGGCCCGTGGGCCCTCAAGGCCGTCGCGCTGGTCGCGGTGCTCGCCGTCTGGGCGGCCGCGGCGCTGACGCTCATCCCGATGCTCTCGGAGAAGATCTCATCCTCCTCCTCCGACGAGGCCACCACGGCCGGCGCCACCACCGACGGCGAGGACGGCGAGGACGGCGGCGAGGACGGCTCGGGCGGCGAGGACGGCGGTGCCGGCGGCTCCGGCGCGGCACCCACCGCGGCGGGCGGACCCGGCCTGATCAGCGGCACGATGCTGGGCGAGGCCCCCGCCGGCGTGACGGTCCGCCTGGAGTCGAAGGCGCTCGTCGACGAGTCGATGCAGCAGGGCGTCCGCACCGTCGGCACCTCGGAGGACGACGTCGCCGGCGAGGGCAAGCGGCTCGCCGCGGCCGCCGTCGCGGCGCTGCCCAGCGAGAGCGACGCCCGCACCAAGACCACCCCCGAGAACGGCGCGTGGGCCTTCCAGGACGTCCGCAGCCCCGGCTACTACCTGCTCACCATGTCGAAGCCGGGCTACCAGACCCAGCGCTTCGTGGTGAACAGCGCCAGCGAGGCGGCCAAGGAGCCGCTCGAGGTCGAGATGGTCCCCGGCAGCGGCGCCCTCCGGGGCCGCATCACCGGCCCGGGCGGACCGGTCGGCGGCGCCCAGGTCACCATCACCGACGGCATCAACACCGTCACCACGAGCACCAACTCGCAGGGCGACGTCGGGGCCTGGTCGATCACCGGCCTCTCCACGCCGAGCACCTACGTCGTCGTCGCGACGCGCCACGACATGAGCAGCGAGGCGGCCTCGGTGCGGGTCGAGCCCGAGGAGACCCGCACGGTCGACCTCACCCTCACCCCCGGCGTCGCCCTCCTCACGGGCAAGATCAAGCGCTACCTGCCGGACGGGTCGAAGGGCCCGCTGCTCGGCGCCACGGTGTCGGTCAGCGACGGCGAGGGCAACATCCGCACCGCCACCACGCTGACCGAGGAGCCCCAGGGCAAGTTCTTCCTCTCGGGCGTGCCGGTCCCCGGCAGCTACACCGTCACCATCAGCGCCCCCGGGTTCCAGTCCGAGAGCCGGCAGGTCGACCTGGTGCCCGGACGGCGTCCCGACCCCGTCTCGACGCTGCTGCTCAGCTCCTCGGGCCGGCTCGTGGGGGACGTGACGATCGCCGAGGAGCCGGCCGCCGCCCCCGCGGCCACCCCCGTCGCCGCGCGCGGCCGGGCCCGCGAGCCGGTGTCCTCCGGGGTGCCGCTGCGCGCCACCGGCCTGGTCCTGACCAACAACGAGGCCACGTACAAGACGACGAGCTCGTCCGGCAAGGACACCTCGTCCTACGCCTTCACCGGCGTCGAGCCGGGCGTGTACTCGCTCTCGGCCGAGTACTTCGGCTACGTCTCGCGCCAGCTCACCGTCCGGGTCACCGCCGGCGGCGAGAAGCGGGCCGACCTGGTCATGGAGCCCGTGGCCGACGGCATCTCGCCCCAGACCTCGACCGTCCGCGGCACCGTGGTCGACGTGGCGACCGCCGAGCCGATCCGGACCTGCGACGACGGCCGGCCGGTCAACCCGGAGGGCTGCCTGGCCGCGACGCTCGACGAGAACGGCAACGGCGTCGCCGACCCGGAGGAGTTCACGACCCGCTTCGGTCCCGAGGACGCCTACACCCTGCCCGACCCCGCCGACGACCTCTGCGAGGAAGCCGTCTCCGCCGGCCGCACCTGCGGCATCGCCCCCGGGCTCTACACCGTGCTGGTCGAGGCCCCCGGCTACCTCCCGAAGTCGCTCGACGTCCAGGTGGCCGAGCGCAGCAACGTCACCGCCCCCGTCGCCGAGCTGACGGCGGTCCCCTCGGTCACCGGGCGGGTCAGCCTCGCGCCGTTGGTCGGCGAGGACTTCGAGGCCCTGGACCCCCAACCCGCCCAGCCGATGCCCGTCACCTGCGTGTGGATGCAGGTCGACGGCACGACCGGCGCCCTGCCCGACTGCACCACCGCCGTCGCTGCGGGCGCCGCGAACGACGCCGCCGCCCAGGCCGACGTGGACGCCTGCCTGCCCGGCGCGTTCTACCAGGTCGGTTCGCAGCCGGGCCGGACCCGCTGGTGCGCCGCCATCGGCGAGGACGACCGGTTCACCATCGAGGCCCCGCGCACCGGCGCCTACACCCTGACCACCGTCCCCGCCGACAAGGAGTACATCGTCTCCCGCTCCGGCACGCTCCTGCTCGACGGCGGCGCCGAGCAGTACAACCCGGTCCTCGACCGGCTCGGCCAGATCATCGTTCGCTCGCTGCAGCCGGAGCCGATCCCCGGCGACGGCGTGGACGACCCGACGGATCGTCTCGTGCCCAGCGACCCGCGGCCGACCCTGACCCTGACCCCGGAGCCGCCGGGCCTGCAGCAGGCGCCCGAGCCCGAGACCGGCGTCACGCGGATCTACCGGGTCCAGCCGGGCTCCTACACCGTCACCGGCACGAGCGGTGCCTACAGCGGCAAGGTGGACGCCGACGTCGTCTACAACCAGGTGCTCACGCTCCGGCTGGCCCTGATCGACCCGATCCCGAACTTCGTCGGCAAGGTCGTCGGTCGCATCGACGGTGCCCCGGTCCCGCTGAACGGCATCCCGGTCCTGCTGCGCGGGGCGACCTCGTTCTCGGACACGGGTGTGCCCGGCTACAGCACGACCGAGCCGACCACCGGAACCGACGGGTGTTTCGCCGTCGAGGCTCGGGAGACCCCCCCGCTCCTCGGATGCACGACCGGGTGGAACGACTCGAACCGGACCGTCATGGGCTTCCTCACCGACACGATGAACAGGATCATCGTGCGGGGCGAGGCCGCGGGCTGGGAGCCCTACCAGCGCACCAAGCAGCGGCTCGTCGTGGGCGGACTCAACACCTTCGAGCTCGCGCCCGCCCCGGTCGACGTCGACGTCGCGGTGACCGTGACCCCGTCGGCCACCACCTCGCCGTTCACCCTGCCCGTCCCGGTCACGGTCGTGGACCCGCCCAACGGGCGCAGCGTCACCGCCCGGCTGGTCGCCGACCCGCTCCAGGCCTCGCGCGGCGTCCTCGAGTGGGACGACGAGGGCGACGACGCCCAGGGCGACGCCCTGCCGCCCGGCCGCGCCATCCCCGGCACCTACCCCCTCAGGATCGAGCTCGAGGGCTACGTGCCCTTCACCGGCACCCTCACCTGCGCCGTCGGCGGCTCGTGCTCCTTCGGCGGCGCCGTCGTCCTGGAGAGGCTCGGGAAGATCGAGCTCACCGTGCGCGGGCGCGACGGCGAGCCCGTCACCGGCGCCGTCATCACGCGGAGCGTCGACGGTGTCGAGGACTCCTTCGAGCAGACCCTCGGCAGCAGCAGCACCACGACCTACGACCGGGTCGTGCCGGGGACCGACACCCGCACGCAGTTCTCCGTGCGGGCCCCGGGCTACGAGCACGCCACGACCCGACTGGTGCAGAACTCGAGCGACGCCGTGCGCCTCGACTGCGAGACCGGGCCCGACCCGACCCGGGTCACCGTCGAGCCCGGCGGCACCACCCGCTGCGACCTGATCCTCACCCGGCTCGGCACGATCCAGGGCGACGTCCTCGCCAACCTCGGCGTCCAGGGCGGCCCCGCCAGCGAGGTCCGACACCCCGAGGACGTCGTGGTCACCGCCGCGCTGTGCACGAACCCGGTCGCCGGGGGGTGCACGGCGGTCTCCGAGCAGGCCGACGAGGTGTTCACCACGACCACCGACGAGGACGGCGCGTTCGTCGTCACCGGCAGCAACCAGGTCGGCCGATCCGGGCTCGCCGAGGGCACGTGGGTGCTCACCGCCGCGGTCCCCGGCTTCGACCAGCGGACCAACCCCGGCAGCGTGCGCGGGCGGGTCGTGCAGGTCGAGCGCGGCGTCCAGACCGCCGACGTCGACGTCTACGCCACCGCGGTCGCGCTCTCGGTCACCGTCCAGGACGCCGTGGCGACCGTCGACGACGCGAGCGTCGTCGTCCGCCTGACCCAGAACGACGACGAGGTCCCCACGGCCGGCGACCCCACCGCCTCGCTCGTCGGCACGGGCGCCGGGGCGCGCTACGTCTTCGACGCCGTCGTCCCCGGCACCTGGACGATCGTGGTGACCGGCCCGACGATCGTGCGCACCACCCAGGACACCACCCTCGTGCCCGGTGACCCCACGCAGGCAGACACCGTCACCGTCGAGCGCACCGAGGCCTCGATCGAGGGCGTCGTCACCGTCGGCGGCTCCGACTCCGACGCCGGCGACGTCGCCGGCGGGGCCACCGTGACCCTCACCTGCACCGACCGTGCGGTGGTGTTCTGCCCGCTCGACCAGCCCGCCCGCGGCACCGAGGGCCAGGAGCTGACCACCACCACCAGCCCCGACGACGGCAGCTACCGGATCGAGAACGTCCCGGCCGGCAGGTACGTCGTCACCTTCACCAAGACCGGGTTCGAGCCCTCGTCGTCGCCCGAGACCACCTTCGCGAGCAGCGCCGTGATGGTGCTCGACCACGCGCTGGTGCCGACCCGCCGCTTCCTCGACGTCACGCTCACCTCGAGCGCCGGCGCCGCGGAGAACCTGTCCGGCACCGTCCTCGCGCTCGAGCCCCTCGGCGGCACCGTCAGCCCCGACCTCGCCCTCACCCTCACCGGCGGCGGCACCGGCTCCTTCCAGCAGGTCCGCTCCGGCTGCTACCAGGTGAGCCTCACCCAGGGCGCCGGCCACCTCGGCACCCTGAGCGGCCCCACCGGCCGCGGCGACACGTCCGGCTGCCCGGCCGGCGCCGCCGGCACCACCGTGGTCCGGGTGCCCGACGGCACCTCCGACGAGCGCAGCGTCCTGGCCTGGACGGTCCAGGCCGCCCGGTTCGGCTACACGCTCAGCGCCGACGCCTGGGAGGGCCACGCCGAGCCCACGACGTCCCTGCGGATCGTCCGGGCCGCCGGCGGCGGGTTCGACCGCACCGTCGCGGCCCCGGCCACGACCACCGGCGAGCTCTGGGTGCCGCCCGGCCGCTACGACGTCACCCCGGTTCTCGCCGGCGTCCCCGCCCAGTGGTGGCCGGTCACCACCTCCACGGTGGACGTGCCCACGGCGTCGCCGGCGACCTTCGCCCTGGCCGAGTCGCTGTTCGAGGTCACCGTGCGGATCGAGGGGTTCGCCGGCGGCACCGCGAACATCCAGGTCTCGCCCGGCACCGGGCAGGACGGCGCCGCGCCGAGCCCCGCCTCCCTCTCCACGAGCACCGGCGAGGTCGTCCTCACCCTCCCCCACGGCGCCTGGCTCTTCGAGGGCGACTGGGCCGACGGTCCCGACTCGGTCCAGGTGACCGTCACCGGCCCGACCAGCGTCACGCTGCGACCCGCACCGGCCGACCCGGACCCCGCGCCCGCCCCGGCGCCCGACGCGGCACCGGACCCGGCGCCCGCACCTGACGGGACCGACGGGACCGGTGGAACAACCGATGGGACCGGTGGAACCGACGGGACCGACGGGACCGACGGGACCGACGGGACCGACGGGGAGCTCGCGCCGTGACCCGGCGGACCGGACGCCGGCTGCCGGGCCTCGTCTCGACCGCCCTGACCGGGGCCCTCGTCGGAGCGCTGGTCGCCACCGCCGGCGCCGCGGTGCCCGCGGCGCCCGCGGCCGCCGCAGCCGCCGCGGCCCCCCCCCGCAGACCCCGGTGCTCACCGACCCCACCACGACGCCCCTGCTGGTCAGCGCGACCCCCTGGACGCCGGCGGTCACGACCCCGTCGTCGGGCACCCCGGTCACCTTCGCGGTCGTCGCCACCCCGGCCGGCGCCTGCACGACGTCGGCCGACCAGCGCACGATCACCCTCGCCGCGCCGGGCAGCTGCGCCGTCACCGCCACCGTCCCGGGCGACGCCACGTACGCCGCCGGCACCAGCGCGGCCAAGACCTTCCAGGTGCGCCGGCCGCGCACCTTCTCCATCACCCCGCCCGCCGACCCGCTGCGCGCCCTCGGGGAGCCCTGGACGCCGGCCTACTCCGGTGCCGGGACCTCGGCGGTCGACCTGACGTCGACCACGCCGCGCGTGTGCACCGTCGCCGCCAACGGCGACGACGTCTCGCTCCTGGCCCCCGGCTCGTGCACCGTGCACGCCGAGGTCGAGGCCGGCGACCAGGACGCCGCGGCCGAGGACGACGAGACCGTGGCCGTCGCCGCGGCCGACCCGCGGCTCACGCTCACCCCGACCACGGGGTCCCGGGTCGTGCGCGGCGAGCAGCCGCTCGTGGTCAGCCAGGACGGCAGCGAGCGCGTCACCCTGACGGTCTCCGACACCGCCGTCTGCGAGGTCCTCGCGGGCCGCACGGCCGTGCGGATGAAGCGGGTCGGGTCGTGCGAGGTCACCGCGAGCGTGCCCGCCGGGGACCTGTACGCCGCCGACTCCGCCGTCGCGACGATCGAGGCGACGGCGCGACCGGTCAGCATCGCCTGGAGCGTGGTGCCGGTCGGCCCCCGCTACCGCGACCTGGTCCGGGTGACGGCCACCGCGACCGACACCGCGACCGGCGAGGCCGTCGCCGGCGCCGGCCACCTCCAGGTCGTCGACCTCGACGCCACGACCCCCGCCGACACCGCCTGGCCCGGCGGCGTCGGGGTCCGCGAGTTCGAGGCCGCCGGCGTCCGCACCTACGTCGTCCGGGCCGGGTTCGTGCCCACCGACACCGGGGTGTGGGCCGAGGTCGACCAGGCCTCCCACGACGTCGTGGTCGGCAAGGCCGACCTCGTGGCGTCGTTCACCACCCCGACGGCCGCCGAGCTCGTCGCCGGCGACACCTGGACCGACGCGGCCGCCCTCACGCCGTCCGACTCCGGCCTGACGCCGGCCCTGAGGTCGACGACGCTGTCGGTCTGCACCGTCTCGGGCAACGACGTCACCTTCCTCACCGCCGGCAGCTGCGCGCTCGAGGCCAGCCACCCCGGCACCGCGCTGTACGCCGCCGCGGCCGTCGTCAAGCGGAGCTTCACCGTGGCCGCCGCCCCGGTCGACGTCGTCGTCACCTCCAGCCCCGCCAACCCGGTCTTCGGCGGCACCGTGACCGTGACCGCCACCGTGCGCGACCGCGCCAGCGGGGCCCTGGTCACCGGGGGCGCCGGCTCCATGACGATCACCGGCGTGCCGAACCCCAGCCCGGCCACCGTCGCCTGGACCGGCGGCACCTACACCCGCACCTTCACCGCCGGCACGGTCGGCACCCTCTCCGCGGTCGCGTCCTTCGCCGGGGTGACCGGGAGGTACACCACCGGCACGGGCAACGCCACGATCACCGTCGGCAAGGCCTCCTCACCCATCACCTGGGACACCACGACCGTCCCGAGCCCGGCCCGCGTCGGCACCACGTGGGTCACCGGCGCCGTCAAGGGGGCCTCGCCCCAGCCGCTGGTCCTCAGCACCGACGACCCCACGACCTGCACCGTCAGCGGCACCACCGTGGCGCTCGTGGGGGCCGGCACCTGCACGGTCAGCGCCGACCAGGCCGAGGGCCCCACCCACGAGGCCGCCCACCTCGAGCACACCTTCGAGGTCGTGCGGCGCCCGGTCACCCTGACCACGACGGTCGACAGGTCGGCCCCGGTCTACGGCGACACCGTCACCGTCACCGTCGTGGCGACCGACACCCTCACCGGTGCCCGGCTGCCCGGCTCCGGCACGATCACCGTCGACGCCCCGGTGACCGGCGACCCCGCGGCCGTCACCTACGCCTCCACCGGACCCGCCATCGGCGCCGCGACCCGCCGGCTGACGGCGGTCCCGGTGGGCTCGTTCACCATCGCGGCGTCGTTCACGGCCTCCCGCACCCACGCCGCCCAGACCGCGACCCGGCCCCTCGTCGTGGGCAAGGCGTCGCAGGCCGTGACGCTCGGGACCGCCCCCAGCCCGGCGTACGTCGGCCAGACCTGGGAGCCGCTGGTCACGCGCGGCCCCTCGACCGGCGCCGTCACCATCGTCCCCACCGGCTCCTGCACGGTCGAGGGCCTCGTCGTCACCTTCACCGTCCCCCCGGGCACCTGCACGGTGAGCGTGACCCAGGCGGGTGACGGCAACTACCTGGCCGCCCCGGCGGTGGAGCGCACGGTCACCGTCACCAGCCGCCCGGTCCGGATCGCGGTGACGACGCCGTCCGGCCCGCCGGAGTTCGGCACGCCCGCCACCGTCGTCGTCCAGGTCTACGACGCCCTCCAGCCGGCCGCGACGGCCGACGTCGTGCTCGGCACCGGCACCGCCGTCGTCGCCGGGTTCCCGGCCTCCGCGCAGTCCTTCGACCCGGTCACCGGCCGGGCCACGCTGACCTACACCCCGACCGCGGCCGGCCCGCAGGACATCGTGGTGACGTTCACGGCCGGGACCGCGCGGCACGAGTCCTTCACCGAGCGGAGGGCGTCGATCACGGTCGCCCTCGCCCAGCAGGTCCTCACCCTCGGTGCCACCCCGGCGAAACCTGCACCCGGCCGGGTCACCAAGACCTGGACGCCGCCCCTGACCAGCACCAACGCGACCCAGCCGATCGTGCTCGCCACGGTGCCGGCCGACTCGGTGTACTGCTCGGTCTCCGCCGGCGTGGTGACCTTCGACCGCGAGGGCACCTGCGAGCTCCAGGCCACGCAGGCCGCCGTGCCCACGAAGTACTCCGCCGCCACCCCGGTGACGATCCTCGTCACCGTCGACCGGATCCAGGTCACGGTGACGCTGCGCGTCACCCCCGTCAGCCCGGTGGACGGCGAGGTCGTCACCGACCTCGCCGTCGACGGCGGCCTCGAGGTCCGCGCCGAGGCCTTCGCCCGCGGCGAGGGTGCCGGCGGGAGCAACCTCAAGATCGCCGGCACCGGTGCGATCGGGATCGACCGCGGCACCGGCGCGGGCGCCACCACGATCGCGCAGAGCACGAACCCCACCAGCGCCTGGTTCGGCAGCGGCCGGTTCCTCGCCGCCACACCGCGGCGGGCTGGTGACCACTACCTCTGGCACGAGTTCGTCCCCAGCGACAGCCGGGTCTACGAGGTCGCGCCGTACGCCGCCCCGGCGGCCGGCCAGCCGCAGCCGCTGCGCCAGGTCGCCCCGACCGCCCACCCGGTCGGGAAGGCACGCCAGACCATCGGCTTCACGCCCCGCACCGGCCCCGACCACGTCGACGGCAGCTGGTTCCCGGCGCCCACCGGCGGCGGTTCCGGCAACCCGGTCCAGGTGTCGGCGGCCGGAGGCTGCACCAGGCGCGGCACGACTGCCGCGCCCGAGGTCTACCTCACCTCGCCGGACACCTGCACCGTGACGTTCCACCAGGACGGCAACGACGACTACCTCGCCGGCGACGCCGAGGTGTCCTTCCAGGTCTACCGGGCCCCGACCACCGTGACCCTCTCGGTCAGCGCGGCACCGACGGTCGGGACGCCGGTCACCGTGACCGCCCGGGCGACCGCCTCCTCCCTCGACGGCGCGGCCGTCCCCGGTGGGTACACGATCACCGTCGAGGGCCAGACCCTGGTCACGACGCCGCGCGCCGACGGCACGGCCACCGTCACCTGGACGCCGACCGCGCGCGGCCCGGTCGAGGCGACCGCGACGTTCCGGCCCGACGACGACAACGCCTTCGCCGACAGCCCGCCGGCCTCGCTCACCGTGGCCGTGGACGCCGGCACCCAGACCTTCACCTCGGCGGCTCCGCCCGCCGACCAGCAGTACGTCGGCGACGCGTGGACCCCCGCGCCGGTCGTCACCCACGGCCCGCCCGACGCCGTGGTCGACGTCGAGGTCACCACGCCCGACGTCTGCCGCTGGGACGGCACGGTCGTGCGCCTCGAGGCCGAGGGCACCTGCTCGGTGACGCTCGGCGTGGCCGAGTCGCCGCGCGGCTCGACCGCCCCCGACTGGCTCCCGGCGGTGGGGCTGACCCGCACGATCGACGTGCGTCGCAACCCGACCACGGTGGCGCTGCCGGCCGACACCTCGACCCTCGTCACCCGGCCCGGCCCGTTCCAGGACCCCGCCCTCACGATCCCCGTCACGCTGACCGGCCGCCTCAGCGGCGACGTCCTCGACCCGGCCCTGCTCTCCGGCACCGTCGTGCTCACCCGCACCCGGGTCTCGACCGACCCCGCCGACCCGCCCGGCCCGGTCCAGCTGGCCCGGGTCGAGGTGGCGGGCGGCGCGGCCTCGGCCGACGTCTCGTTCACCCGCTTCGGCAGCTACACCGTGACCGCGACGTTCGTGCCGGCCGACCCGACGACCTTCGCCGGCAGCACGACGTCCTACCAGGTGCTCGTGCGCAAGCACGCCCAGACGATCACCCAGGTCGTGCCGCCGACGCCGGCCAAGGTGCTGACCTCCTGGACCTACCCGTTCGCCGAGAGCTCGGCCGGGCTGCCCGTCGTCGTCACCCCGACGTCGGCGTCGTGCACCACGGCCGGCGCCGTGGTCACCTACAGCGCCGTCGGCCCCTGCACGATCACCTTCTCCCAGCCCGGCGACGACTACTACGCCGCGGCGGCCGCGCTCGGAGCCACGGTCGCCGTCGAGAAGAACGCCACCAGCGTCGCCGTGCGGGTCCCCGCCGGCGCCACCGTCGGCGCCCCCAGCGACCTGACCGCGACCGTCACCTCGGTGCTCCCGGTGCCGGGCACGGCGCCCGCGGGCGGCACCGTGCAGTTCACCGCTTCCGGTCAGCCCGTCGGCGACCCGGTGCCCGTGGTCGGCGGCACCGCGACCCTCCCGTGGATCCCCTCCGCGGCGGGCACCACCGCCGTGCGGGCCGTCTTCGCACCGACCGGGACCTCGGACGCCGTCTACGCCGGCAGCAGCGCGTCCGGCTCCTCCACGGTCGCCCCCGCCCCGGTCACGGTCGTCGTCACGATCACCACCGACGCCATCCGGGCCGCGGTGTCGCCCGAGCGGCCCGCGGCGGGCACGGCGACCGGGGACGTGGTGTTCCGCACCGCGGGCGGGCCGGCCCTCGGCACCGGCACGCTGGTGGCCGGCGTCGCCCGGATCGACAACACGCTCGACCCGACCGCCGACGTCGTCGTCCAGGCCTCCTACGCCGGCGACGGCACCCGGGCCGGCCAGGGCGGCTCGCTGCGGCGGGCGCTCCCCACGGTCAGGGCCACCCCCACCGGCGCCTCCGGCTGGCAGCGCACCAACGTGACCATCCGCTACGAGTGCACGCGGCCGGCCGGCGCCGAGCTCGCGGCCCCGTGCCCGGCACCGCACGTCTTCTCCGCCGACGCGGCCGGGCAGTCGCACACCGAGACCGTCCGGGCCACCAACGGCGGCCGGGCCACCGTCACGGTCGGGGGGATCGACATCGACAAGACCGGGCCGGTGCCGGTCATCCAGGGCGTCACCCGCAACGCCGACTACCGCGACGTCCCGCCGCGCGGGCGCTGCGTCGCCTCCGACGCCCTCTCCGGCCTCGTCGGGTGCGTGACCAGGACCGTCGTCACCGGCCGCGACACCCGTGAGCTCGTGGCGACCGCCACCGATCGCGCCGGCAACCGGACGGTCGTGACGGTGCCCTACCGCCAGCTCCACGAGTGGGTGGTCGGGGCCCCGCTGCGCGGCAGCCGGTTCGCGGTCAAGCCCCGCTCGACGGTGCGCATCGCCGCGACCAGCACCCGCCGCAAGCCGCAGCTGATGCTGCCCCGCAAGGGCGGTGGCTGGACCCCCGGCCCGGTGATGGTCGCGGAGAGCGTGCGCGAGGGACTCTTCCTCTTCACCACCGCCGCCCGGCTCCCCGCCGACGTCGGCGGGCACCGCCTCGGCGTCCGGCTCCAGGGCACCAAGCAGGTGCAGGTCATCCGGTTCGTCGCCCGCTGAGCGCCCTCGGGCCCGCCCCGTGCGGCGTGAGGTCCGTCACCGGGCCACGCTCCGCGGCGCCCGGAGTTTGACGGGCGGGCGAAAGGGAAATGAACGCAGGACGTCGTGTCTCCTACGATGGGCGTCCAGCCGGCCGCACCCTCGCGGCTCACCACGTCGCCGCGGAAGCAGGTCACCTTGTCGGAGCAGCTCGTCGACGAGCCGGTCGGGACGACCGACGGCTCCGACGCGCCTCCGGCCTACAACCCGTGGCAGTCGGTGCTCTGGGCCCTGCGGGTCTCCTGGCTCGGCGCGATGGCGTGCGCCCTGGTGCTGGAGCTCTCGGGGCTGGTCGGCGAGGAGTCCTACTGGTGGCACTCGACGTTCGTCGACGGCCTCAGCTACGTGCTCGACAGCGTCGTCATCTGGGTCATCCTGGTGGCCGTCATCGGCCTCACCAACCGGGTCATCCTCTCCCTCGGGATCGTCGCGGCGGGCACCATCACGCTCGCCGCCGCCAACAGGGTCAAGCTCGGGCTCCGCTCGGAGCCGGTCTACCCGAGCGACGTCGACTTCCTGCGGGAGCCCAGCTTCCTGCTGACCCAGGTCTCGGTCGGCACCCTCGTGGTCGCGGGCATCGGGCTGGTCGTCCTGGTCGCCGTCGCCTGGCTCGTGGGGCGGCGCTTCGAGCCCCGGATGCCGCGGATCTGGCCGCCGCACCTCTCGGTGCGCCGGCAGCTTGTCGCGGTCGGGGTGCGCGCGGTCCTGGTGACCCTCGCGATCGGCACGATCCAGAACACCGCCAACTTCAACGACCCCGGCAACCCGCTGCGCGGGCTCTACGAGGTCGGCGACCACGAGTGGAAGTACTGGAACCAGCGCAACAACTACCTCGCCAACGGCTTCGTCGGCGGCTTCCTCTCCAACATGCCGACCGTGGCGATGAAGACCCCGGAGACCTACTCCGAGGAGACCATGGACGCCCTCGCGACGCGCTACGAGCGCGCCGCGGCCCGGATCAACCGCAAGCGCACCGGGACCCTCGACGACGCCAACGTCGTGGTGGTGCTCAGCGAGTCGTTCACCGACCCGACCCAGCTCGAGGGCTTCGAGCTCGCCCGCGACCCGATCCCGAAGATCCGCAAGGTCATGCGCGAGGGCAGCTCCGGCACGATGATGGCCCAGCTCCTCGGGGGCGGCACGGCCAACATGGAGTTCGAGACCCTGACCGGCGAGTCGATCGGCCTCTTCGAGCCGCAGCTCAGCACGCCGTACCAGATGCTCGTCTCCGACTACGACCAGTACCCCTCGGCGGTGGGCTGGCTCGGGGCCAACGGCCACAAGCCGATCGCGGTGCACCCCTACCTCACGTCGTTCTACAAGCGCGACAAGGTCTACGAGACCCTCGGCTTCGACGAGTTCATCCACGACACGACGATGACCGAGACCGAGAGGATCGACGACAACGAGTTCATCTCCGACAAGTCGGCCTTCGACGAGGTCGCCCGGCAGATCGACGACGCCGACGAGCCGCTGATGGTCAACCTCGTCACGATGCAGAACCACATCCCGGTCGACGGCAACTACGACGACCCGATCCCGGTCACCGGCGTCGAGGGCGACCAGGCCGACCGGATCTCCAACTACGCCCGCGGCCTGAGCCACACCGACGACGCGGTGGCCGACTTCCTCACCCGGATGAAGCGGTCCAAGGAGCGCACCGTCGTGGTGTTCTACGGCGACCACCAGCCCGGCATCTACGACTCCTCGATCGCCGACCAGAACCCCGGCCTGGCGCTCTACACGACGCCGTTCTTCCTCTGGGACAGCGCCGGGACGCCGAAGCAGCAGCTCCCGCAGAGCAGCCCCACGCAGTTCCTGCCGATGCTCTACGACATGGTCGGCGCGCCGGTGCCGCCCTACTACGTGCTGCTGAACCGGCTCCGCACCTACGTCAGCGCGCTGGAGCAGGGCCGGATGCTCTCCCCCGAGGGCCAGGAGATCACCGAGGACGACCTGCCGCCCCGGGGGAGGCGTCTGCTCGAGGACGTGCGGCTCGTGCAGTACGACTTCTCGATCGGCGACCGCTACTCCGTCGAGCGGATGTGGCCCGGCTCGATGCGCTGACCGGCGCGCCGACCCGTCCTCCCTAGGCTCGTGGGGTGCCCGCCTCCCTCCCGGCCTTCCGCACCGCCGCCCGCCTGCGTCCCGTGGACGTCGTCCAGCCCGGCAGCCGCGTCGGGCCCGCGCCCTTCGTCGCCGCCGAGCGCGACCTGGCCGCCGGTCGCCCGGCGCCCGCCGACGTCGTCCTGCGCTCGGGGCGCACGACCTTCCGCGCGACGTGGGACGGCGCCGTCGTCGCCCTGGAGGTCGGCGACGCGACCGGCGGGGTCAGCCGCCACGTCAGCCGCCGGCACGGGCACGGCGTCTCACCGACCACCCTGGCCCTGGCCCTGACCGGTCCGTACCTGGCGGCGTTCGTGCGCGAGGCCGGCACGTGGGTGGCCCGCGCGGTGGTCGACCTGACGCTGCTGCCGGGCGCGCCCGACGTCCACGACGAGGACTGGCTGGCCGGGCTGAGCGCCGAGGGCGAGCGCACCGGCACCTTCGGCCAGCTCGGGTTCCGCGACGTCCGCACGGTCACCCACGCCGACGGGACCGCCCACCTCGACGGCGACCGGGTGCTGCTCACCGCGACCAGCGCCGGGCCGGGCGGCTTCCGGACCGGCCACACCTCGGTCTGGGCGCTGGACCCGCTGCGGCTCGAGGTGGAGCACCGCGCCGACCTGTTCTTCCGACGGCCGGAGCGGCCCGGCACGTTCGGCGACCACGCCACCCACCTGGTGCGCGACGGCGACCGGTGGCTGGTCGCGACCAGCACGTGGGGCGACTTCGACAAGCGCACGAACCCGCGGGTGACCACCACCCTGGCGACCGAGACGGCCGACGTCGACCTGCTGCACGGCCACCACGTGCTCGACACCGTCCCGCTCGACCTCCCGGTCGAGGGCCTCGACTCGGTGGGCCGCTGGGACCCGCACCTGGTGCGCGCCGACGGCGGCTGGCTGGCGACCTACGTGAGCGCGCGGCGCTTCTTCTCCTTCCACCCGGTGCTGGCCCAGGGTCGCGACCTCGACCGGCTGCGGCTGCGCGCCGCGGCCACCGACCGCACCGCCACCGAGGGACCGACGCTGACCCGCCTCGGCGAGGAGTGGGCGGTGCTGGCCTCCGACGGCCGCGACAACCCCCGGGGACGGCGCGCGGCCTACCCGGTCTACGACCTCGACCTGCGCCAGCGGGGCACGCTCGACGCCGACTACCCCACGAACATCCCGTGGCCGACCCTGGTGCCGAGGCCGGGCGGCCCCGCCGTGGTGGGCTTCGACGGCACCCCGGCCGGTGGACCGCTGCTCGACTACGGCACCCACGGGGACCTGGTGGTGCAGCTGCCCGTCGTCCCGTAGTATCCCTAGTAGATCACTAGCCATTGACGGTCACGGGAGCCCAGCGATGAGCGCACTGCACCACGACACGAGCCACCACGAGCACCACGCGGGCGCGCCCCGCCGGCGGGCCGACCTCGACCACGACCGGGTCGCGATCCTCGCCATGATGGCGATCCTGGCCCTCACCGTCGCGTGCTTCCTGGCCCAGGGCCTGCTCGCCCGCTGAGGGTGCCGCCGGCGGCGCCGCGGCCCGCGGTTGCGGCCCTGGTGGCCCGGTGACCACCCGGACTGCGCTACGGTCGGCTGCTGCGTGACCTCACTTCCCTGGGGTCCGCACCCCTGACCACCACCGAGAGGACGAGTAACTCCCATGAACCGCACCGAGCTTCGTGAGGCCATCGCGACCGAGACCGGCCTCAGCGGCGCCCAGGCCGACCAGGCCCTCACCGCCGTGCTGGACGCCATCACCGGCGCCCTGGCAAAGGGCGACAAGGTCACCCTGCCCGGCTTCGGCACCTTCGAGACCCGCGAGCGCTCCGCCCGCCAGGGCCGCAACCCGCAGACCGGCGAGGCCATCGACATCGCCGCGAGCACCGCTCCCGCCTTCAAGGCCGGGTCCGCGCTGAAGAAGGCTGTCTCCGGCAGCTGAACCACGCACCACGCACCACGTCGAAGCCGGTCCCGCCACGCGGGGCCGGCTTCCGTCGTCCTCGACTCCTCCCCCAGGATCGAGACACGGCGGCCCGGAGCAGCGATGATGTCCTGGATGGACGGGATGCGGCTCGGGCCGGACGACGCGCTGCTCCGCAGCATGGTCGACGCGACTCCCGACAGCCTGTGGCTGCTCGGCACCGACGGGGTGACCCGCTACGCCAACCAGCGCCTCGCCGACCTCGTCGGGTACCCCCTCGACGAGCTGCTCGCGCTCTCCCCCCTCGACCTCGTCGATGCCCAGGGCCGTGAGGACCTCGAGCGCCACCTGGAGCAGATGCGCGCGGGCCACCCCGGCGGCGAGAACGAGGAGGTCCGGCTGACCCGGCGCGACGGCAGCTCGGTCTGGACCCTCGTCAGCTGGGCCCCGGTGCCCGGCGCCCCCGGCACCTACCTGCACCGGCTCACCGAGTACACCGAGCGGCGCCGGCTCCTCGAGGAGCTGCGGCTGCGCGAGGAGCAGCTCTCCACCGCCGGCCGGATGGCCCGCCTCGGCGGCTGGACGTGGGACCTGCGGCGCAACCACGTCACCTGGTCCGACGAGCTCTTCGAGATCCTCGCCGTCGACCCGGACTCCTTCGGCGGGAGCTGGGAGGCCGGGTTGTCGGCGTTCCACCCGGAGGACGCCGAGCACGGCCGCACCGTCATCCTCGAGGCGCTCGAGCACGGCGACGACTTCTCCTGGGAGGGCCGGGTCACCACCCCCGACGGCGCGGTGCACTGGATCCGCAACTTCGGCGTGCTCGAGCGCGACGAGGCCGGCGCCGTGGTCCGCGCCACCGGGACCAGCCAGGACATCACCGACCTCCAGGCCGCCGACCACGCCGCCGGCGAGGCCACCCGCCGGGTCGAGATGCTGCAGCGGCTCGCGGCCGCCGCCAACCGGTCCGCGACGGTGGCCGAGGCGCTCACCGAGTCCGACCGCGTGCTCCGCGGCGTGAGCCGGTGGCGCGCGATCGGGTACTTCGCGACCGGTCCCGACGCGACGCTCGTCGAGGGCCGGCTGGCACACCCGGGCGGGCCCGACCTCCCGCCCGCCGACGTGGAGCTGGCCGAGGTCGCGCGCCGCAGCCGTCGCCTCGAGATGGCACCGCTGCCCGACCGCCCCGGCACGGGCATCCTGTCGGTGCCGGTCGTCACCGACGACGAGGTCGTCTACGTCTACCAGCTCCTCGCCGACACCGAGACGCCGAGCGCGGCCACCCTGTCCCTGGTCGCCCAGAGCAGCGACCAGCTCGCCTGGGTCGCCGAGCGCGAGCGAGCCGCGGCCCGGCTCGCCCAGGCCCACGACGACGCGATGACCGCCTCCCGCATGAAGTCGGAGTTCCTGGCCATGATGAGCCACGAGATCCGCACGCCGATGAACGGCGTCATCGGGCTCAACGACCTCCTCCTCGGCACCGCCCTCGACGACCAGCAGCTGCGCTACGCCCAGGGCGTCCGCAGCGCGGGCCTCACGCTGCTGGCGCTGATCGACGACGTCCTGGACCTGTCGAAGGTCGAGTCCGGCAAGCTCGAGCTCGAGGTCACCGAGTTCGACCTGCGCGCCCTGGTCGACGAGACCGTCGGCCTGCTCGCCGCGCCGGCGCGGGTCAAGGGGCTCGACCTGGTCGCGGGCTACGGGCCCGGGGTGCCCCGCACCGTGCTGGGCGACCCGGTGCGCCTCGGCCAGGTGATCGCGAACCTCGGCTCGAACGCGGTGAAGTTCACCGACGCCGGCACCGTCGTCATCGAGGTGACCTGTCCCGACCCCGACGAGCACGACGGCCACGTCGTCCTGCAGGTGGAGGTGCGCGACACCGGGGTCGGCATCGCGCCGGCCGACGTCGACGGGCTCTTCGACGCCTTCACCCAGGCCGACCTGTCGACCACCCGCAAGCACGGCGGCACGGGGCTCGGGCTGACGATCTCGCGCCGGCTGGTCACGACCATGCAGGGCGAGATCGGCGTCCGGAGCACGCCGGGCGAGGGCAGCGTGTTCTGGTTCACCGCCCGCCTCCGGGCGGCTCCGCCGGGGGCCGACACCGCGCTGCCGCCGCTCCAGCCGCTGCACGGGCTGCGGGTCCTCGTCGTCGACGACAACCCGACCGCGGCGGCGTTCCTCGCCCGCCAGCTCAGCGAGTGGGGCCTGTCCCCCGTCGTCGTCGGCTCGAGCACCGACGCGATCGCGACGCTCGCCGCGGCGGCGGCCGACCGCACGCCGTTCGACCTCGCCGTGGTCGAGCTCGACCTGCCGGGCACCGACGGGCTGGCGCTCGGGCACCGGATCAGCCTCGACCCCGGCCTCCCCGACGTCGCCCTCGTCCTGGTCGCCGCCGACGGCGGCGTCGACCCCGCGACGGCACGCGAGGCCGGCTTCCGCACGGTGACGGCCAAGCCCGTGCGCGTGGCCGCGCTGCACGAGGACCTGCTCGACACCGTCACCGACACCGTCGCGGCCACCGTCACCGCCAGCGTCGCCGTCACAGGAGACGACGCCGGGGGCGCGCCGGCCCGCACCCGCCGGCAGCGGCCGGCGCGCGCCGTCCGGCCCGGGGGGACCGGCCTCGACCTGCACGTGCTGGTGGTCGAGGACAACGCCGTCAACCAGCTCGTCGCGATCGGCGTCCTGGAGAACCTCGGGTGCACGGTCGTCGCGGTCGAGAACGGCGAGGAGGCGGTCATCGCGCTGCGTCCGGGGCACGCCTTCGACGTCGTCCTGATGGACTGCCGGATGCCGCGCCTCGACGGCTTCGGCGCCACCCGGGCCGTCCGCGCCGTGGAGACCGGCCACCGCGTGCCGATCATCGCGATGACCGCCTCGGCCCTGCCCGGTGAGCGCGACCGCTGCCTGGACGCCGGGATGGACGACTTCCTGACCAAGCCGGTCGACCCGGTCCGGCTCGCCGTCGCCCTGGCCCGGGCGGTGGGGACGCGCACCGACGCCGGCCACCCGGAGACACCCGTCCCCGCCGCCGGGCCGCCCGCCTCGGCGGACCACGACGTCCTGGACGTGGAGCGGGTCGAGCTCCTCGACGAGCTGGTCAAGGACGGCGTCAGCTTCTTCGAGCGCGGCCGGATGTCGTTCCTGGCGCGCATCGACCAGTCCATGGAGCAGATCGGGCGCGCGGTCGCCGAGCGCGACGTCGAGGGCACCGTGCAGGGCGCCCACCAGCTGCGGGGCAGCGCGCTCAACCTGGGCCTGCGGCGGGTCGGCGCCACCGCCGAGGACCTCGAGCAGGCCGCTCGCGACGGCTCCCTCGACCGCGCCGACGCACTGTTGCTGGCGCTGCGCCACGCGGTGGTCATCGGCGTCGAGGCCCTGGTCGGCGTCGACCTGCCCGGCCGGCGTCCACCCACCCCCTGAGCCAATCACCACCACCCCCACCCCCGCTGACCCGTCAGTGATCAGCGACGGGTCAGCGCCAGGAGGAGGGTGACCCGTCGGTGATCAGCGACGGGTCAGCGCCAACAGGTGGGTGACCCGTCAGTGATCAGCGACGGGTCAGCGCCAACAGGTGGGTGACCCGTCAGTGATCAGCGACGGGTCAGCGCCAAGAGATGGGTGACCCGTCAGTGATCAGCGACGGGTCAGCGGGGGTAGGCGGGGCGTGTCCTAGGGTGGTGTGATCCGCGCCACCCCTGCGGACCGCCCAGGTCGCCTCATCCGGTGACCGTCGCACCGAACCGAACGGACACCACCCATGTCAGTCACGTCGTCAGTCACGTCAGTCACGTCGTCACCCCCGTCCCTGCCCGCCGACGTCTTCGAGCTGGGCGCCGAGCACGAGCAGGTCGTCTTCTGCCAGGACGCCGCCACCGGGCTGCGCGCCATCGTCGCGATCCACTCGACCGCCCTCGGCCCGGCCCTCGGCGGCACCCGCTTCCACCCGTACGCGACGACGGCCGACGCCCTGGCCGACGTCCTCGACCTCTCCCGCGGGATGTCCTACAAGGCCGCGCTGGGCGGGCTCGACCTGGGCGGCGGCAAGGCCGTCATCATCGGCGACCCCGCCACGCTCAAGTCCGAGGCGCTGCTGCGGGCCTACGGCCGGTTCGTGGAGTCGCTCTCGGGGCGCTACCTGACGGCGTGCGACGTCGGCACCTACTCCGAGGACATGGACCACGTCGCGCGCGAGTCGCGGCACGTCACCGGCCGCACGGTCGCCCACGGCGGCGCCGGCGACAGCTCGGTCCTGACCGCCTACGGCGTCTTCCGCGGCCTGCTCGCCGCGGCCGAGGCCGCCTGGGGCACCGACAGCCTGGAGGGGCGCGTGGTCGGCGTCTCCGGGGTCGGCAAGGTCGGCCGGCACCTCGTCGGCCACCTCGTCGAGGCCGGCGCCTCGGTGGTCGTCACCGACGTGTCGGACCAGGCGCTCGACCGGGTCCGCGACGAGCACGCCGGCGTCCGGGTCGCGGAGTCCACCGAGGCGCTGGTCGCCTCGCCGCTGGACGTCTACGCCCCCTGCGCCCTCGGACACGCCCTGACCGACGAGGTCGTCGAGGTGCTCTCGGCCCGCGTCGTGTGCGGCGCGGCCAACAACCAGCTCGCCCACCCGGGCGTCGAGAAGGCCCTCGCCGACCGCGGCGTCGTCTACGCCCCCGACTACTGCGTCAACGCCGGCGGCCTGATCCAGGTCGCCGACGAGCTCGAGGGCTTCTCCTTCGCCCGGGCCCAGCAGCGCGCCGCGCGGATCTACGACACCACCCGCGCCGTCCTCGAGCTGGCCGCCTCGGACGGCGTCCCGCCCGCGACCGCCGCCGACCGGCTCGCCGAGCGCCGGATGCGCGAGGTCGGCCGCCTGCGCGGCATCTGGCTCGGCTGAGACCCGCACCGCCCACCGCGGCGCGCTCCCGTCGTGGGAGCGGGCCGTGGTGGCGGTGCGGTCACGGACGTCGCCGCCGGACCGCGGGCGCACCGAACCACGGCGGCACCACACGGGTCAGGCGCGTGCGAGCCTCAGGGACGGCGGCGCAGCACCGTCACGAGGGTCAATCGCGGGAGCGGTCGGGCGCGTAGCCCGACCACTCGTCTGGCTCCTCGACCGGGTCGACCGGGTCGACGTCGTCGGATTCACCACCGTGCAGCTCCTTGGCCAACGCCCCGAAGTCCGTCTCATGCGTCCGGTACTTCAGGTCGCGCGCGACCTTCGTCTGCTTGGCTTTCGCTCGGCCGCGGCCCATAGGGTCCAGCCCCCTCGCACACTTGGCCGGGCGCCGATGGCGTCCCGGACTCTCTCAACAGGATCTCGTGGGGGCAACGCTACCTGTTCGCTGTCTGTTCCGGCACGTCGGGATCACGTTCGGACGACGTTTTCCTACCAGTCCGGGTGCTGGCCCACCATCCGCACGGTCGCGGACTGCTCGGGGTCGACGTCGACCTGCCCCGCGACCCACGCGCGGACACCCAGCCCGTCGAGCAGGTGCAGGGCCGCCTCGACCGAGTCGGGGGGGCACAGGGCGATCATCCCGACCCCGCAGTTGAGGGTCATCTCGAGGTCGGCCTGGCTCAGCGAGCCCACCTGGCGGACGACGTCGAAGATCGGCTGGGGGTTCCAGGTGGCCCGCTCGACGCTCGCGCGCAGCTCGGCCGGGAGCACCCGCGCGAGGTTGGCCGCGAGGCCGCCGCCGGTGACGTGGGACATGGCGTGCAGCTCGACCTGGTCGGCGAGTGCCAGGCAGTGCTTGGCGTAGATCGTGGTCGGCTCCAGGAGCTCCTCGCCGAGGCTCCGGCCCAGCTCGGGGACGTGGCGGTCGAGCGACCAGCCGGCGTCGGCCAGCAGCACCTGGCGCACGAGGGAGTAGCCGTTCGAGTGCAGGCCGGACGACGCCATCGCGATGACGGCGTCGCCGGGGCGGACCCGGCCCGGGCCCAGCAGGCGGTCGGCCTCGACGACCCCGGTGGCGGCACCGGCGACGTCGTACTCGTCGGGCGCGAGCAGCCCGGGGTGCTCGGCGGTCTCGCCGCCCACGAGCGCGCAGCCGGCCTCGACGCACGCCTCGGCGATGCCCTTGACGATCGCGGCGATCCGCTCGGGGACGACCCGACCGGTGGCGATGTAGTCGGTCATGAACAGCGGCTCGGCCCCGCAGACCACCAGGTCGTCGACGACCATGCCCACGAGGTCGAAGCCGATGGTGTCGTGCTTGTCCATCGCCTGGGCGATCGCGACCTTGGTGCCGACACCGTCGGTCGACGTCGCGAGGAGCGGGCGGGTGTACTGCGTCAGCGCGGTGGCGTCGAAGAGCCCCGCGAAGCCGCCGAGCCCGCCGATCACCTCGGGACGGGAGGCCTTGGCCACCGAGGCCCTCATCAGCTCGATCGCGGTGTCGGCGGCCTCGATGTCGACGCCGGCGCGGGCGTAGGCGTTCTGCTCGGTCAACGTCGGTCCGTTCGGGGTGGTGGGGTCGGTCACGGGTTGTTGAGCACGGGGAGCGCCTTGCCGTGCGTCGGCGAGGCGATCGACGTCTCGAGCAGGTGCTTGCCGAGCAGGCTCTCGTCGGGCAGCTCGACCGGGTACTCGCCGGTGAAGCACGCCTGGCACAGCTGCGAGGCCGCCTGCTTGGTCGAGTCGACCATCCCCTCGAGGGAGATGTAGCCGAGGCTGTCGGCGCCGATGCTGGCCGCGATCTCCTCGGGGCTGAGCCCGTTGGCGATCAGCTCGGCACGGGTGGCGAAGTCGATGCCGTAGAAGCACGGCCACTTCACCGGGGGGCTCGAGATCCGCACGTGCACCTCGGCGGCGCCGGCCTCGCGCAGCATCCGCACCTGGGCGCGCTGGGTGTTGCCCCGGACGATCGAGTCGTCGACGACGACGATCCGCTTGCCGCGGATCATGTGGTCGAGGGCGTTGAGCTTGAGCCGGATGCCCAGCTGGCGCAGGGTCTGGCTCGGCTGGATGAAGGTGCGTCCGACGTAGGCGTTCTTCACGAACCCCTGGCCGAACGGGATGCCGGACTCCTCGGCGTACCCGGCCGCGGCCGGCGTCCCGGACTCGGGCACCGGGATGACGAGGTCGGCCTCGACGGGGAACTCGCGGGCCAGCTGGCGGCCCATCTCGACCCGGGACTCGTGCACGCTGCGCCCGCTGATCGTGGCGTCGGGGCGGGCCAGGTAGACGTACTCGAACACGCAGCCCTTGCGGTCGGGCTCGGCGAAGCGGTGCGAGCGGAGACCGTTCTCGTCGATCACGATCATCTCGCCGGGCTCGACCTCGCGGACGACGCTGGCGCCGATCGTCGCCAGCGCGGCGTCCTCGCTCGCCACGACCCAGCCCCGGTCGAGCCGGCCGAGCACGAGCGGGCGGATGCCCTGCGGGTCGCGGGCGGCGTAGAGGGTGTTCTCGTTCATCCAGACGAAGCAGAACGCGCCGCGCAGCAGCGGCAGCACCTCGAGCGCCCGCTGCTCGAGCGAGGTGTCGGGGTGGTGGGCCAGCAGCGCGGTCACCAGGCCGGTGTCGTTGGTCGAGACCTCGACGGGCCGGGTGTGGAGGTCGAGCTCGTCGTCGGGGCCCGGGAGGGCGTCGACCATCTCGCGCAGCTCGTGGGTGTTGATCAGGTTGCCGTTGTGGCCCAGGGCGATGGAGCCGTCGGCGGTCGGGCGGAACGTCGGCTGCGCGTTCTGCCAGGTGCTCGCGCCGGTGGTCGAGTAGCGGGCGTGGCCGACGGCCAGGTGCCCCTTCAGCGAGGCCAGCGTCGTCTCGTCGAAGACCTGGGAGACCAGCCCCATGTCCTTGTAGACGAGGATCTGGCGGCCGTTGCTCACCGCGATGCCGGCCGACTCCTGGCCGCGGTGCTGGAGGGCGTAGAGGCCGAAGTAGGTCAGCTTCGAGACGTCCTCGCCCGGCGCCCAGACCCCGAAGACGCCGCAGGCGTCCTGTGGGCCCTGGTCGTGCGGGTCGAGTGCTGCGGTGAGGCGGCCGTCGCCACCGGGCCTGGAGCCTTGACTGCTCATGAAGGGCACGACCGCATCCTAGTCGAGGCTCGGCCCCGGTCCCCCAACGGCGACGGTGGACGAACCGGGGACGGATGCGGCCCACGGTCGTACCCTGGAGGCACCCGCCCCTCCCCTCCCCTCCCCTCCAGGATCCCCCTGTGCCGGACGGCCGCCCCCGTTCCCCCGCGCGCATCGACGTCACCACGTGGTCCGACGTCGGCTCCCGCGACGCCATGGCACTGGTGGCTGCCTCGGTGGCGGAGATGGTCGGGTTCGAGATCGCGATCATCAGCGTGGTCGTGGGCGAGCACATGTACTCCATCTCGGTCGAGGGCAGCAACGACGCCACCGACGCCATGGCCGGGGTCGCGACGCCGATCTCGCTCGTGCTGCCCGAGCTCGAGCGCGCCGACGACTGGGGCCGCTTCCGCTTCGTGCCGCACGACCGGATCGCGGACGGCGACACCGCGGTCGGCTGGATCCCGCAGATGGAGACCGTCGACGCCGTCGACGCCTGGCACCCGCTCGACCTGCTCCTGGCCCCGCTGTACGACGAGGGCGGCCGGATGATCGGCGTGCTGTCGATCGACGTCCCGATCTCGGGCCGGCGGCCCGACGTCACCCAGCGCCACCTGCTCGAGCGGTACGCCGCGCAGGCCGAGCGCACGCTGCGGATGGCCATCGAGCGCGAGGAGCTGGCCGAGCGGATCCGGCTGGCCGAGGCCGCGCGCCGGGTGGTGCGGTTCGCGACGTCGCAGGACGACCTGGAGAGCGTGCTCGACGACTGCCGCGACCCGCTGCTCGAGGGGCTGCGCGCCGACTACCTCGAGATCCGCACCTACTCCACGCCGGAGCTTCCGGGTGCCGGGTCGCCGTCGTCCGGGCTGGCCCACGAGCTGAAGGAGACCATCCGCGCCGTGGCGCGCCGCTGCTGGACCGAGCAGCGGGTGCTGCTGAGCGGGCCCGACATCGAGCGCGACCCGCTGCTCGACGACCAGACCCACGCCCGGCTGGCCGAGGCCGTCGCCCTGCTCGGCCTCGGCTCGGCGATGGTGGTGCCGCTCGGGTCCGGCCGCGCCAGCCTCGGCCACCTGGTGCTCGGTCGCAAGGACCCCGCCATGCGGTGGAGCCCCGACGAGCGGGCCGGCGCGCTCGACATCGCCCGCGACATCGGCCAGGCCGTGGTGAACTCCCGCAACCTGGCCCGCGAGCAGCGCCTGGTCGGCGAGCTGCGGCAGCTGGCGGCGTACAAGTCGCAGGTGCTCTCGACGGTGTCGCACGAGCTGAAGAACCCCCTGACCGCGGTCTCCGGCTACGTCGAGATCCTGGAGGGCGACCCCGGGATCACCGGCTCCGGACGACGCTCCCTCGGCGCCCTCGACCGGGCCGCGCGCCGGATGGGCCGGCTGGTCGACGACCTGCTCGAGCTCTCCGAGGTCGAGGACCCCGAGGCGGCCGTGCCGTCGGAGGTGATGGACGTGCGCCCGATGGTCGACGGCGCCCTCGAGCTGCTCCGGACCGCCGCGAGCCGGCGCGACCTCGACGTCCGCGTCGACGCGCCCGGGCACCCGGTGCTCGCGTGCTGCTCGCCGGCGGACCTCGAGCGGGTGCTGACCAACCTGGTGAGCAACGCGGTGAAGTACACCCCTCGCGGACGCGCGGTCACCGTCCGCGTCGTCGAGCACCCCGACGTCGTCGAGCTCGCGGTGGCCGACGACGGCATCGGGATCTCGGAGGCCGACCAGCAGCGGCTGTTCACCGAGTTCTTCCGCTCCACCAACCCCGACGCCGTGGCCCAGCCCGGCACCGGACTCGGGCTGACCATCAGCGCCCGGATCGTCGAGCGGCACGGCGGCCGGATCGAGGTCGAGTCCGAGCTCGGCGAGGGCAGCACGTTCCGGGTCTTCCTCCCCCGGCCCGACGCCGCCTGAGCGGTCCCGCCCGGGCGGGCGCTCAGGCGGGCGCGGCCGCGGTGTCGACCCGGCGGGCCCCCGTGAGGCCGAGGATGCCGCGGGCGACGTCGGCGGCCTGACCCCGGATCTCCGGGATCGCGGTCGACTCCCACAGGGTGCCCTTGCGCGGCGGGCCGACGGCGAACAGCCCGGGCGCCACGGTGCCGTCGTCGCCGACCAGGCGGCCCTCGTCGGTGGTGTCGATGCCGAGCAGCAGCGGGTCGGGACGGACCAGGCCGCGCTCGCGGAGGGCGAGCAGCAGCGGGTCGTCGCTGCGGGTGATGTCGGTCGACGGGCCGGTGCAGTTCACGACCGCGCCGGCGACGAGCGGGGTGGCGACGCCGGCGATCCGGACCTGGCAGGTGGCACCGCGGTCGGCGATCGAGAGCAGGCCGCCGCCGAGCACGCTGAGGCGGCCGTCGTCGGCGTAGACGCGGATCCGCTCGGCGACCTCGGGCGCCATCCGGTGCCGGCGGGTCTCCCACTCGCGGGCGTGCACGGCGAGGAAGCGGCGCCGCTCCTCGATCGGCAGCCGCTTCCACAGCGACGGCGTCGCGGCGCGCAGCCCGTCGACGACGGCGCGCCAGCCGACGCCCTGGGCGGCGGCCGCCGCGACCTGCTCGGTCACGTGCTCGGCGAGCAGGTCGGCGGTCAGCGGGCCCTCCGGCACCGGCTGGACCCACGCGGTCGAGAGCTGGGCGACGTGCTGGTGCGGGAGGAGGCCGTGGCGGCTGACCATCACCACCCGGCGGCCCGGGCCCTCCTCGAGCAGGGTGATGACGGTGTCGACCGCCGTCAGGCCGGTGCCGACGACGACGATCGTCGCGTCGTCGGGCAGCATCCGCAGCCCGGCGAGGTTCCACGGGTCGGCCAGGTGCCAGGGCGCCGCCGGGAGCGCGTCGCCGTCGATCACGAGGGGCTGCGGACGGCGGTTGCCGTAGGCGAGCACCACGCTGTCGGCGTGGGTGACGACGTCCTGGGCGTGGATGTCGAACCCCGCCCCGTGGCGGTCGGTGTGCGGCACGACGTCGTCGACCCGGCCGGCGCGGATGCTGAGCCGGTAGTCGGCCACGGAGGCGAGCCGGTCCTGGAGGTAGGTCGCGAAGTCCAGCCGCGGGAGGAAGGCCTGCGGGTCCTGGCTGCGCCCGGTCGCGCGCGCCCAGTCGATGAGGTCCGACGGGACGTCGGCGAACGCGCTCATGTGCCGCGAGCGGACGTTGAGCAGGTGGTGCGGGTCGTTGGTGCCGTAGGCGATGCCCCGCCCGACGATCCCGCTGGCCTCGTGGATCTCGACCCGCAGGTGCGGGTTGTCGCTGCTGGAGAGCAGCTGGATCGCGGTCAGGACGCCGCTGGCCCCGCCGCCGATGATCGCCGTCCGGTGGACGGACCGGGGGTCCTGCGTGCGGGACGGGACCTGGAGTGGCGCGACAGACATGGCGTAATCCTAGCGACCAAGTACAGAAAGTCCGGTAATCGACCACCCCCGGACGGCGGGTCGTCACCGGGCCCGGCCGGAGCCGTCCTAGAGGGCGCCGAGGTTGCGCAGCAGGAACGCCTCGGCGAGCACGACCTTCTCGAACTCCGCGAGGTGCAGTCCCTCGTTGGCGCCGTGGGCGCGGGTGTCGGGGTCCTCGACGCCGGTGACGAGCACGCTGGCCTCGGGGAACGCCTCGAGGAACTCGGCGATGAAGGGGATCGAGCCACCGACGCCCATGTCGACCGGCTCGGTGCCGTCCCAGGCCTCGGTGAAGGCCGCGCGCGCGGCGTCGTAGGCGGGTCCGGTGGCCTCGATCGAGGTCGCCTCGCCGGTGTCGACGGTCGTGACGGTCAGGCCGGCGCCCCACGGGACGTGCTGCTCCAGGTGGGCCGTCAGCCGGGCGAGGGCGTTCTCGGTGGTGTCGCCGGGGGCGACGCGCAGGCTGAGCCGGGCGCGGGCGGCCGGCGTCAGGGTGTTGCTGGCGCCGTCGACCCGGGGGGCGTCGAGACCGGTGATGGTGAGGGCCGGCTGGGTCCACAGCCGCTCCACGACCGGGCCGCGGCCGATCCAGTCGACGCCGGGCGCCGCGCCACTCTCGGCCCGCAGGCGCACCTCGGGGTACTCGACGTCGGCCGCCGGACCGCTGTGCAGGCCCTCGATCGCCAGGGCCCCCTCGTCGTCGTACAGGGAGGACAGCAGGCGGGTCAGGGCCATGATCCCGTCGGGCACCAGGCCGCCCCACATGCCGGAGTGCACGGCGTGGGTGAGGGTGCGCACCTCCACGTCGACCCGCACGAGACCGCGCAGGCTGGTGGTCAGCGCCGGCTCGCCGATGTCCCAGTTCCCGGAGTCGGCGATCACGATGACGTCGGCGCGCAGCGCCTCCTGGTGCTGGGCCAGCAGCGCCGGGAGGGTGTCGGAGCCGACCTCCTCCTCGCCCTCGATGAACATCGTGACGCTGACCGGGAGGTCGTCGCCGAACACGCGGAGCGCGCCGAGGTGGGCGGCGATGCCGGCCTTGTCGTCGGCCGCGCCGCGGGCGTACAGGCGCTCGCCCCGCTCGGTCGGCTCGAACGGCGGGCTGTCCCAGTCGGCGTGGTCGTTCTCCGGCTGGACGTCGTGGTGGGCGTAGAGCAGCACCGTCGGCGCGCCGTCGGGGCCGGGCTTGTGGGCGATCACGGCCGGGGCACCACCGTCGGCCGAGACGATGTCGACGCTGGCGAAGCGTTCGGCGCGCAGCAGCTCGGCGACGGCCTCCGCGCTGCGCTGCACCTCGGCCGCGCGGGCCGGGTCGGCGCTGACCGACTCGATCCGCACGAGGTCCTCGAGGTCGCGCCGGATGCCCGGCATGAGGTCGGTCACCTGGGCACGGATGGCGTCGCTCGCAGCAGTCATGCCGGCCAATCTAGACCGGCGGGCGTGAAGCACCCCGCGCCCGGGCATGATGCGCTGCGACCACGTCGTCGACACCTGCTGGAGCCCCGATGTCGCAGCGCCCCCCTGAGGACCCGCACTCCGCCGAGACGCAGGTCGGGCGACCCGGCGGACCGGGCAAGCCGCCCCCTACGCCGTCCGGACCGCCGTCCGGACCCCCGTCCGGACCGCCGTACGGGCCGCCCTCGGGACCGCCGTCCGGGCCGCCGTCCGGGCCGCCGTCCGGGCCGGGGTACGGGCCGGGGTACGGCGCCGCGCCGTCGGGACCGCCGGCGGGCTGGCCGCCGCAGCAGCCCGGTCCCGGGTGGCAGGGCGGACCGCCCGGTGGCTACCCGCCGGGTGGCCCGGGCGGCCACCAGCCGGGCCGCGGGGGATCCTCCAGGCTGCCGTGGATCATCGCCGCGGCGGTGCTGGCGATCGTGCTGGTCGGCGGCTCGGTCACCGCGTTCGTCCTCGCCGGCGGTGACGACGAGGACGAGAAGGCCGGCGACCCCGGCACGTCGTCGAGCGCGACCGAGAGCAGCGACGTGCCCTCGCCGAGCAGCCCGGCCGCGCCGACGTCGCCCGCCCCCTCCTCGGCGGCCCCGTCGTCGGCGGCCCCGTCGGCCCCGACGGCACCCGACCCCTCCACCTCGGCCGGGCCCAGCCTCGAGGCGATGCAGATCGGGGGCTCCTGGACGGGCACCTACCGGTGCCCCCAGGGCCCCACGAAGCTCAGCCTGACCATGGCCTCCCTCGGCGACGGCGACGGCGTCCAGGCGGTCTTCGAGTTCGGGCCGACCCGGAACGGTCCCGACGTCCCCAACGGCGCGTTCCTGATGGAGGGCACGATCACCGGCGGCGAGCTGGTCATGGCCGGCACCGAGTGGCTCGACCGGCCCACCGGCTACTCCTTCGTGGGCCTGCGCGCCGACGTCCCCGACGCGACGGTCGACTCGCTGACCGGCGAGGTGACCGACGGCGGGTGCAGCACCTTCAAGATCTCCCGCTGACGCTCAGGTCAGCGGGAGGTACGGCGTCAGGTCGGTGCGCTCGCCGGAGGCGGAGGCCCGGGCGTGGGTGAGGGCGTCGATCCAGGCCAGCGCGCCCGTCGCGAGCGCGATCCACGTCAGCGCGTCGGTCTCGACCACCGCGGGCGGGGTGCCGCGCGTGTGACGGACCCCCTCGATCACCTGGACGGCGGCGTAGGGCGGCACCCGGACCTCGACCGAGCGACCGGGCGCCCGGTCCTCGAGCACCGCGAGGTAGTGCTTGACCAGGAGCTTGAGGTCGGCCCGCTCGTGGCTGCCGGAGGCGAGGCGCTCGGTCGCCTCGCGCACCAGGGCGGGATCGGCAGGACGGAGTCGGGCGGCCACGTCGACCGAGGCTACGGCGTGGACGGCAGTGGTGCCGTTCCGCCCCGGCCGCGGCCGCCCGGGTCTAGCATCGCGAGGGTGGCCGGCTCCCGGATCGCACGACGACGACGACGCACCGCCCGCACGACGGAGACGAGCCCGTCGACGCGGTCGCCGGCCGCCACGCCCAGCCCTCCCGAGGACCCCGACGCCGTCGCGCGCCTCGCCGAGGCCCACCCCGTGCCGGGTCCGGGGACCGAGCCCACCCGGATCCGTCGCCTCCAGGGTGACCACGGCGACCGGGGCGACCGGGGCGACCGGGGCACCGACGGCGGACCCGGGACACCGGGCGGTCCGGACCTGGCCGCCGCCCTGCGCCAGCAGCGCGCCCGCGCGACCGGGAGGTCGCGCGCCGACGTCGACCAGGAGGCGGCCCAGGAGGGCGCGCAACGCGCGCACGGCGAGGCGCTGCTCACCTCCTCGGGCCAGCGGGCGACCGCGGAGGCGCAGCAGTTCGGGCTGGGCGGCGGCGTCGACCACCAGCGCATCGGCGCCACCGTCACCCGGAACCGCGCGCTGGGCGCGACCGGCTTCGAGGAGCTGCTCGCCGGGCGCCGGGCCCGCACGGAGGCGATGACGCCCGTGTCGGGCGCGACACCGGCGCTCGACGACCACCAGGGCGGGCTCGCGGACCGGGAGGCCCGCCTCGCGGAGCTCGGCGAGCTGCGCACCGAGGCTTCCCGCCGCAGGGACGGGCTGGCCGCCGTGCTCGCCGGGGCGCGGCAGACCGCGGCCGAGGCGGTCGCGGTCGCCAGCTGGGACCAGGACGCCCTCGACCAGCTCGCGTCGGCCGCCTCCGCGGCCCTGGCCGGGCTGAGGGTGAGCAGCCTCGAGACCCCCGAGCAGGTCGAGGCCGGGCTCGGCGCGGTGCAGGCCGCGATCATGCCGCTCCTCGAGCGGGCCCGCGAGGACATCGCCTGGATGGAGCGGCTGCAGCCACGCACCGAGACCGAGATCCGGGAGGGGGTCGAGGAGTTCCGGACCACGGGCTCGACCGACGTCATGAACAGCGCGATGTGCCAGCTGTGGCAGAACATCCTCTCCCTCGGACCGGCGATCCCGCGGGACGGCGTCCTCGTGGAGGCCAAGTTCGACGGCCTCTCCAGCGAGATCGACCGCAAGACCTCCTTCGACCCCGGCAGGGCGACCGCCGCCCTGACCTCGGGCACGCCGAGGCAGAAGGCCGACCTGGTCGAGCAGCTGCAGAAGCGGGCCTCGACCAAGCGCTCCATCACCGAGGTGCTCAAGGTCGGCTACGACACCAAGAAGCTCCTCACGATCGTGAACCGGCTCGCCAGCGTCGACGGCCTCGCGACCGCGATGGCCCACACGACCCCGGACGACCTCGACCAGATCACCCAGCGCTGCCGGGACACCAAGGTCCTCCTGCGGATCTACCGGGCGGCGAGGCTCGACGGGGCACGGGTGGTGAAGTGGCTCGTCACCAGCGCCCGGCACGACGCCGCGGACCTCGACGCCTACCTCGCGCGCGGTGGCCGGGCGTGGCTCGACGAGACCTGCGGCCCTCCGGCGCTCCCGGCCGGGGTCACCAAGGAGGACATCGTCCGCGACGCGCAGCCGAAGGAGGGCTCGGCGCGGCCACCGACGAACGGCTTCGCCGGCAACCGGAGGTTCACCAACCAGGGGAAGCTGCCCGACATGCTGCTGCCGGCGAGGACCGCCGAGAACAAGGCCATCACCTACCGGGAGTACGACGTGCAGCGCTACCGACCCGGCGTCGACCGGGGCAGTCGACGGTTCGTCAAGGGCAGCGACGGCCGCTTCTACTACACCGACGACCACTACCAGACGTTCCGCAAGTTCGCGCCGTGAGGCTGACCGCGCCCGAGGCGCTCCACGTCCAGGTCGAGGACCCCAGCGCCTTCGCCGAGACCTACACCCGGCTCCAGGGCGAGTACCCGGACGCCCGCACCTGGCGGGTGCGGGGCGACCGCATGGCGACCGCCCGCGCCGCGTTCGACGAGCTCGGCGCCGCGCTGCAGCTCCCGTACTACTTCGGCGGCAACTGGGCCGCCCTCGAGGACTGCCTCCTCGACCTCGACTGGGCGCCCGCGACCGACTACCTGCTGCTGGTCTGCGACGCGCACCTGGCCCTCGCGGACGAGCCCGACCAGCTGCCGAGCCTCCTGGGCTCGCTGGTCCGGGCCCACGAGGCCTGGCAGCCGCGCTCGTTCCGCACCGTCCTGCAGGTGCCCGCCGGGGCCGACGACGCGCTCTGGTCGCGGCTGGCGCAGGCCGGACAGGCCACCGCCGTGTAGACAGGGGCCGTGGACGCCACCGCCGCCGGCCGCACGGCCCGCACCCTCGAGACGCTGCACGCCCTCAGCTACTTCGCCCCGGAGGTCGACGCCGAGCTCGTCGCGCTCGGCGTCCGGACCGGGAGGGCGACCTACTTCGCGTCGCGCTCGGCTCCCATGGGCGCCGTGGGCGCGGGCACCGTCACAGCGACGTTCTTCGTCTTCAACCCCACCCTGGTGGCCCGGCTCGTCCCGGCGGTCTGGGCGGCCGCGGCACCGGCCGACGTGGTCGCGGCCCGGTTCCGCGCGGTCGACGCGGCCTACCGCCGACTGCTGGGCGACGAGGCGGTCGCCGCGCCCGAGATCGCCGAGGCCGCCGACCTGACCCGCGCCGCCGTCGCCGGGTGCGACCCGGCCGGCCGGCCGCTCTACGCCGCGCACGCCGACCTCGCCTGGCCCGACGAGCCGCACCTCGCGCTGTGGCACGGGCTCAGCCTGCTGCGCGAGTACCGCGGCGACGGTCACGTCGCGGCGCTGCTCTCGCACGGTCTCACCGGCCTGGAGTCGCTGGTGACCCACACCGCGACCGGCACCGGCTTCACCGAGCCCGCGGCGAAGCTGACCCGCGGCTGGTCCGACGAGCAGTGGGCCGGGGCCGTCTCCTCGCTCGCCGAGCGCGGGCTCGTGGACGCCGGCGGCGGCCTCACCGAGGCCGGCGTCGCCCTGCGCGCCTCGATCGAGGCCGCGACCGACGAGCTGGCGCTGGCGCCGTGGGCGACCCTCGGCGAGGCCGGCCGCGAGCGGCTCGGCGCGATCGGCAAGCCGCTGGTGATCCGGGCGCTCAAGGCCGGGGCGTTCCCCGCCGGCGTCTTCGCCTGAGGACCGTCGCGTGCCCGAGGGCGACAGCGTCCACAAGCTCGCGCGGCGGCTCGACCGCTCGCTGCTCGGGCGCACCGTCGTCCGCTCCGACCTGCGGGTCCCGAGGCTGGCGACCCGCGACCTGGCCGGGCGCCGGGTCCTCGAGCACGCCACCCACGGCAAGCACCTGCTGACGCGGTTCTCCGGCGACGTGACCCTGCACAGCCACCTGCGGATGGACGGCGAGTGGTCGGTCACCGGGCCCGGCAAGCAGCTGCCGCGGCGGCTGCAGCACGAGGTCCGGCTGGTGCTGGTGCTCGACTCCGGCTCGACGGCGTGGGGACTGCGGCTGCACGACCTGGCCCTGGTGGCCACCACCGACGAGGCCTCGATCATCGGCCACCTCGGGCCCGACCCCCTGCGGGAGGACTGGGACGCCGCAGAGGCGGTGCGCCGGCTGCGCACCGACCCCTCGCTGCCGTTGGTCTCGGCGCTGCTCGACCAGACCCGGGTGGCCGGCCTCGGCAACCTGTGGGTCAACGAGCTCGCCTTCCTCACCGGCGTCAGCCCCTGGACGCCGATCGGCTCGGTCGACGTCGAGCGGCTGGTCGCGCGCGCCGCGACGGCGCTGCGCCACTCCGCCCTGGTGCCCGGGGCCTACCAGGTCACCACCGGCTCCAGCCGGCGCGGCGAGGACCACTGGGTCGCCGGCCGGCAGCGGCGTCCGTGCCTGCGCTGCGGCACCGAGGTGCGGATGGTCGCCGAGCTCGCGAACGACCCGGCGAACCGCCGCACCTGGTGGTGCCCGCACTGCCAGCCCGGCCCGGGCCCCGAGACGCGACGACCGGCCTGAGGGCCGCGCCGGTCAGGGTCAGGGGCAGTCGATCGAGACGTCGGAGACGCGCACCAGGCGCGGCCGGTCGACGTCGTCCTCGACCTTGCCGGTGGCCCACCAGAGCCGGATGCCCTCACCGTGGACCTCGAGGACGGCGAGGTTGTTGTCGAACCAGGGGCCCTCGACCAGCCGCCACGAGAACGGGGCGTCGGGCACCTTCGCCGACCGGGCCACGACGTGGCCGAGCGGGCCGGCGACGCCGTAGGAGAGGGCGGCGGTGGCGAAGCGCCACTTGCGCGAGAGCGGGTTGCGGATCGGCGAGCAGACCGCCTGGAGGATCCGGCTGCGCACGCCGGGCAGCGGCTTCACCGCCGACAGGTAGCTGTGGTGGACGTCGCCGGAGAGGAAGGTGATCGTCGCCGGGGCCCGGCCGCGCTCGCCGCGGCCGACCTCGAGGGTCATCCGGGCGACCTCGCCGAAGCCCTTCTGGAACGCCGCCCAGTGCTCGAGGTCGACGGTCTGGCGGATCTTCTCGCCCAGGCCGGTCAGACGCCGTCCCCAGCCGCCGCCGGCGAGGGCCTCGGAGAAGGCCTCCACGTAGTGCAGCCCCGGCGCCAGCAGGAACGGCAGCGAGGTCGCCACGAGCAGGTGGTCGACGTCGCCGCGCAGCTGGCCGTCGAGCCAGGCCAGCTCCTCGTCGTCGAGGATGCTGCGCTCGTCGTCCTCGAGCACCCGCGCCGCCCGGGAGTCGACGACGACCAGGCGGGCCTGCGGGCCGAGGTCGCGCGCGAAGCTCCAGCGGTACGACGTCGGCTCCTGGTCGGCGCGGTCGGCGAAGGCGTCGAGGACGTCGCTGACGTCGAAGCCCGGCTCGTCGGCGTGCTCGACGACCAGTGACCAGATCGCGTCGTCGGCGCGCTCGGACGGCGTCATGTTGCCCAGGTGCTGGTAGACCCAGTACGACGCCAGCCCGCCGACGATCCGGTCGTGCCACCACGAGGTGGCCTCCATCTCGTCCTTCCAGGCGCGCGAGGTGTTCCAGTCGTCGCGGATGTCGTGGTCGTCGAAGATCATCAGGCTGGGCAGCGTCGAGAGCAGCCAGCGGTTGACCGGGTCCGACCAGGCGAGCCGGTAGAGGTGGGCGTACTCCTCGTAGTCCTTGAGCTCGTCGCCCGGCTCGCTGTCGAGACCGCGGCGCTGCTCGATGAAGGCCTGCATCTCCTTCGTGGTCTCGTCGGCGTAGACCTGGTCGCCCAGGAACGCCACCAGGTCGGGCCAGCGCGGCCCGTCGCCGTGGGAGCGGTCCGGGTCGTCGGCGCCGGCGTCGGTGAGGCCCGCCATCCGCAGCGCGAAGGCCCGCAGGGCGTCGACGCCGTGGGTGGCGTTGCCCTTCTCGTCGTGACCGACCGAGGTGCGGCACGAGCCGTAGGCCAGGCGCAGGGGCTTGCCGTGGTCGAGGGTCGGCACCACCGACGGCGGCAGGTCGGAGCCGGGGTCGGGCCACACCACCTCGTCGTCGACGGTCACGACGTAGGGGTAGCGCCGGCCGCGCTCGAGCCCGTCGAGGCAGACCATCGCGTAGTGGTGGCCGTGGACGGCGAACGACGCCGCCTCGGCCGAGGGGCCGCCCTCGGTCGTCACCCGCACCCGGGCGGGGCCGTCGACCTCCACCCAGATCGAGGCGGAGACCTCGTCGACGTGCCGGAGGAGGGGACCGAGCACGAGGGAGGTCATGCGGACATGCCTACCAGGAGCGGCCTCAGTCGCCCGGCCACTCGCCGGTCCAACGCTGGAACCCGCGTGCGGAGGCCCGCTGGAACAGCGCCTTCACCACGGCGAAGATGGCCCCCTGGATGGTCGCGGCGAGCACGACCTGGCCGAGGGAGTACTCCGACTCGAGCGGCTTGGGCGGGTCCTCGCTGTCGACCGGGACGACCTTGGTCCACACCACGGTGAAGACCTGGCGGGCGATGAGGGCGGCCACGATACTGCCCACGATGCCCCACGGCTTGTAGAGCACGCGGGCGGCCTTGCCGCCCTGCGCCTCGACCTTCGGCTGCTGCCTCACGACGACCGCCTCGACCGGACGACGCGCACGACCACGACGAGCAGGAGGACGGCGGCGCCACCGGCGGCCACCTTCACCCCGAGGTCCTTGGCCTGCGTCTTGCGCTCCTGTAGCCGCCCGGTCAGCTGGTCGACGGTGGCGGCGAGGTCGGCGCGGGTGCGCTCGATGTCGGCCTGGATGGCCTCGGGGTCGTTGGAGTCACTCATGGTGTCCGCCCTTCAACGTGTCGACGTCCTGCTTGACGCCCTCGACGGCCCGGGTGGGGGCGACTCCCCCGACCTCGCCCATCTCCTTCTTGCCGAGCAGCGCGGCGACCGCCGCGGCGGCCAGGACGACCACCGACACGATCAGCGCCGAGAGCCAGGCGGGCAGCACCTCGGCCAGACCCAGGACGGCGGTCGCGAGCAACCCGAGGACGCCGTACAGCGCGAGCAGCCCGGCGACGCCGAAGCCCGCGATGCCGGTGACGCCGTGCTTGACCTTCTGCGCGGTCTCGGCCTGGGCCAGGCGGATCTCGTCACGGATCAGCTGGCTCGACTGGTCCGAGAGCCGGGAGATCAGCTCCCCGGTGCTGGTGGCCTCGCCGGGCTGACCGGCCGGCTGCTGGGGATGACTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP040695|3864361:3923810|3869128_3869785_-|WP_138876702.1|DBSCAN-SWA
MAELEKAFLEIEGGAKVPCLYNPETLSVGRRNNWTSNPMPGKGVPTLQYAGATSGWMRLDLVFDTTSDGTPVSVHTGKILGLMDVDPNLPGSDETSNNVRPPTLTFHWGDLHSFVAVVQDLKLTFTYFSSSGVPLRARMLLELRQYEESHAFGPQNPTSGTPKPHRTHRVLPGETLDRISARYYGNATRWRMLADANGLQDPLAVRPGTILDIPRLEN
>NZ_CP040695|3864361:3923810|3886336_3892564_+|WP_148240859.1|DBSCAN-SWA
MADHSPHAPLPPGVTTAPVLRTAAGVELAVPVTVTNTAAAPRVLTVTPLGVDPVWVVGPPLRTATLGPGASQELTVALHPPQGTLPASYPLVVTVQALDPATGLTDGSRPGLAETTLLVNPRTTLSVSLEPAEPSAIAKARFTVVVRNGGGVATDVALSVTNPSIGYVKLRRQLVTVPAQGEVRVGARARMNRPRMAGYGSRAAFAVTASATESVRHTVGTLHQRALMGPWALKAVALVAVLAVWAAAALTLIPMLSEKISSSSSDEATTAGATTDGEDGEDGGEDGSGGEDGGAGGSGAAPTAAGGPGLISGTMLGEAPAGVTVRLESKALVDESMQQGVRTVGTSEDDVAGEGKRLAAAAVAALPSESDARTKTTPENGAWAFQDVRSPGYYLLTMSKPGYQTQRFVVNSASEAAKEPLEVEMVPGSGALRGRITGPGGPVGGAQVTITDGINTVTTSTNSQGDVGAWSITGLSTPSTYVVVATRHDMSSEAASVRVEPEETRTVDLTLTPGVALLTGKIKRYLPDGSKGPLLGATVSVSDGEGNIRTATTLTEEPQGKFFLSGVPVPGSYTVTISAPGFQSESRQVDLVPGRRPDPVSTLLLSSSGRLVGDVTIAEEPAAAPAATPVAARGRAREPVSSGVPLRATGLVLTNNEATYKTTSSSGKDTSSYAFTGVEPGVYSLSAEYFGYVSRQLTVRVTAGGEKRADLVMEPVADGISPQTSTVRGTVVDVATAEPIRTCDDGRPVNPEGCLAATLDENGNGVADPEEFTTRFGPEDAYTLPDPADDLCEEAVSAGRTCGIAPGLYTVLVEAPGYLPKSLDVQVAERSNVTAPVAELTAVPSVTGRVSLAPLVGEDFEALDPQPAQPMPVTCVWMQVDGTTGALPDCTTAVAAGAANDAAAQADVDACLPGAFYQVGSQPGRTRWCAAIGEDDRFTIEAPRTGAYTLTTVPADKEYIVSRSGTLLLDGGAEQYNPVLDRLGQIIVRSLQPEPIPGDGVDDPTDRLVPSDPRPTLTLTPEPPGLQQAPEPETGVTRIYRVQPGSYTVTGTSGAYSGKVDADVVYNQVLTLRLALIDPIPNFVGKVVGRIDGAPVPLNGIPVLLRGATSFSDTGVPGYSTTEPTTGTDGCFAVEARETPPLLGCTTGWNDSNRTVMGFLTDTMNRIIVRGEAAGWEPYQRTKQRLVVGGLNTFELAPAPVDVDVAVTVTPSATTSPFTLPVPVTVVDPPNGRSVTARLVADPLQASRGVLEWDDEGDDAQGDALPPGRAIPGTYPLRIELEGYVPFTGTLTCAVGGSCSFGGAVVLERLGKIELTVRGRDGEPVTGAVITRSVDGVEDSFEQTLGSSSTTTYDRVVPGTDTRTQFSVRAPGYEHATTRLVQNSSDAVRLDCETGPDPTRVTVEPGGTTRCDLILTRLGTIQGDVLANLGVQGGPASEVRHPEDVVVTAALCTNPVAGGCTAVSEQADEVFTTTTDEDGAFVVTGSNQVGRSGLAEGTWVLTAAVPGFDQRTNPGSVRGRVVQVERGVQTADVDVYATAVALSVTVQDAVATVDDASVVVRLTQNDDEVPTAGDPTASLVGTGAGARYVFDAVVPGTWTIVVTGPTIVRTTQDTTLVPGDPTQADTVTVERTEASIEGVVTVGGSDSDAGDVAGGATVTLTCTDRAVVFCPLDQPARGTEGQELTTTTSPDDGSYRIENVPAGRYVVTFTKTGFEPSSSPETTFASSAVMVLDHALVPTRRFLDVTLTSSAGAAENLSGTVLALEPLGGTVSPDLALTLTGGGTGSFQQVRSGCYQVSLTQGAGHLGTLSGPTGRGDTSGCPAGAAGTTVVRVPDGTSDERSVLAWTVQAARFGYTLSADAWEGHAEPTTSLRIVRAAGGGFDRTVAAPATTTGELWVPPGRYDVTPVLAGVPAQWWPVTTSTVDVPTASPATFALAESLFEVTVRIEGFAGGTANIQVSPGTGQDGAAPSPASLSTSTGEVVLTLPHGAWLFEGDWADGPDSVQVTVTGPTSVTLRPAPADPDPAPAPAPDAAPDPAPAPDGTDGTGGTTDGTGGTDGTDGTDGTDGTDGELAP
>NZ_CP040695|3864361:3923810|3867365_3869129_-|WP_138876701.1|DBSCAN-SWA
MAELGIAPTVTVGGAALRSQWLDLLASVRIDLAIGLSGRTVLRFRDRGFALSTSQEFAMGVEVEVTAGGNQLMIGEVTGVVLEQGAGQTPVLVVTVDDKACRLNGSTKNRTFLNQTYSDVVRKIIGESGLSVGSVGATSPAHAYQLQAGSNLAFLNAICSRAGLAWWVEGVALNVVPVGTAGATVPLALGTDDLTSFSVRATNTGPAQVVVRGWNPDQQAVVSGEHTTSVTGESAFVAKAAGRATRPSRGATDVILAAPALDAGEAGTMARARFAEASSAAVVAKGGGAINSRIKLYDKVKIANAGPASGSYLVTGLEHVYSHSAGFRTHFTAGPVRPAGLVDLLGTPPPDSGMAVSGVLAALVTNLKDPDNKGRIAVKYSAVSEEVESAWARMVVLGAGKDRGMLFYPEVGDEVLIAFENGDTRRPVVLGGLFSAKNTLPVGSGTAVANNKIKYRRITSRLGHMVELADGEQPGEQHILLQHQEKKHQIKISGEEVEVISDGLPITLSNGQAKVVLAKNGDITLDGNNIEIKAKAGIKVTANGQVAVKGTAGTEVGGSTVKVKADGMASVEASGPLTLKGAMVAIN
>NZ_CP040695|3864361:3923810|3914390_3915740_-|WP_137294517.1|DBSCAN-SWA
MTAASDAIRAQVTDLMPGIRRDLEDLVRIESVSADPARAAEVQRSAEAVAELLRAERFASVDIVSADGGAPAVIAHKPGPDGAPTVLLYAHHDVQPENDHADWDSPPFEPTERGERLYARGAADDKAGIAAHLGALRVFGDDLPVSVTMFIEGEEEVGSDTLPALLAQHQEALRADVIVIADSGNWDIGEPALTTSLRGLVRVDVEVRTLTHAVHSGMWGGLVPDGIMALTRLLSSLYDDEGALAIEGLHSGPAADVEYPEVRLRAESGAAPGVDWIGRGPVVERLWTQPALTITGLDAPRVDGASNTLTPAARARLSLRVAPGDTTENALARLTAHLEQHVPWGAGLTVTTVDTGEATSIEATGPAYDAARAAFTEAWDGTEPVDMGVGGSIPFIAEFLEAFPEASVLVTGVEDPDTRAHGANEGLHLAEFEKVVLAEAFLLRNLGAL
>NZ_CP040695|3864361:3923810|3919461_3920310_+|WP_138876721.1|DBSCAN-SWA
MDATAAGRTARTLETLHALSYFAPEVDAELVALGVRTGRATYFASRSAPMGAVGAGTVTATFFVFNPTLVARLVPAVWAAAAPADVVAARFRAVDAAYRRLLGDEAVAAPEIAEAADLTRAAVAGCDPAGRPLYAAHADLAWPDEPHLALWHGLSLLREYRGDGHVAALLSHGLTGLESLVTHTATGTGFTEPAAKLTRGWSDEQWAGAVSSLAERGLVDAGGGLTEAGVALRASIEAATDELALAPWATLGEAGRERLGAIGKPLVIRALKAGAFPAGVFA
>NZ_CP040695|3864361:3923810|3879907_3880549_-|WP_148240856.1|DBSCAN-SWA
MNTCALLGWGVGANVGAPTGCVRAISAFARDGHRAATRLPGPGRREREVVTGNVNAPHTRRFARLVVPVCLAVLALAGCGDDDDGDENPVLDLEVGDCVNAPEEIKAQISDISTVACDEPHDQEAYAVADYEPADQDVDGDVFPGDDALTAFADGRCAEEFKGYVGVDYLDSRFYFTYLYPSPRSWQSGDRAVVCLVMEAGRQLDESVKGTGL
>NZ_CP040695|3864361:3923810|3902660_3902939_+|WP_134766683.1|DBSCAN-SWA
MNRTELREAIATETGLSGAQADQALTAVLDAITGALAKGDKVTLPGFGTFETRERSARQGRNPQTGEAIDIAASTAPAFKAGSALKKAVSGS
>NZ_CP040695|3864361:3923810|3916186_3916771_+|WP_148240864.1|DBSCAN-SWA
MLAIVLVGGSVTAFVLAGGDDEDEKAGDPGTSSSATESSDVPSPSSPAAPTSPAPSSAAPSSAAPSAPTAPDPSTSAGPSLEAMQIGGSWTGTYRCPQGPTKLSLTMASLGDGDGVQAVFEFGPTRNGPDVPNGAFLMEGTITGGELVMAGTEWLDRPTGYSFVGLRADVPDATVDSLTGEVTDGGCSTFKISR
>NZ_CP040695|3864361:3923810|3878196_3879414_+|WP_148240855.1|DBSCAN-SWA
MPAATARTADPALAAVRTHQAAARRAEIATLVAVLDWATEHTTDADPAAMTFGERALTLGGPGCPAIEEFAAYDLAAALGSSTESGLKYLARALELHHRLPRLWAAVLAGRLPVWKAAKIADATMRLPLDGATHVDARLAQAVSTITYAQLDRLVDEAIARHAPDQATAGRDQRHVRVDLDHATIDGHVRLDALLTVPDALDLEHALQTSAQALADAGCDQFLDVRRSIALGDLARGDQPLDLAGRTLVVHLHQDSPDVGRCETTRTPVTVETIETWCATAAKVVIKPVIDLEQHVHVEAYEAPDRLREHVELRDLTCVFPHCRRPATRCDLDHVVPYSAGGTTSSDNLAPLCRRHHRAKTHSHWTYRMTDPGTYHWTAPSGLTYRRDHHGTTPLDPPPAEPAEP
>NZ_CP040695|3864361:3923810|3911008_3912847_+|WP_148240863.1|DBSCAN-SWA
MRPTVVPWRHPPLPSPPLQDPPVPDGRPRSPARIDVTTWSDVGSRDAMALVAASVAEMVGFEIAIISVVVGEHMYSISVEGSNDATDAMAGVATPISLVLPELERADDWGRFRFVPHDRIADGDTAVGWIPQMETVDAVDAWHPLDLLLAPLYDEGGRMIGVLSIDVPISGRRPDVTQRHLLERYAAQAERTLRMAIEREELAERIRLAEAARRVVRFATSQDDLESVLDDCRDPLLEGLRADYLEIRTYSTPELPGAGSPSSGLAHELKETIRAVARRCWTEQRVLLSGPDIERDPLLDDQTHARLAEAVALLGLGSAMVVPLGSGRASLGHLVLGRKDPAMRWSPDERAGALDIARDIGQAVVNSRNLAREQRLVGELRQLAAYKSQVLSTVSHELKNPLTAVSGYVEILEGDPGITGSGRRSLGALDRAARRMGRLVDDLLELSEVEDPEAAVPSEVMDVRPMVDGALELLRTAASRRDLDVRVDAPGHPVLACCSPADLERVLTNLVSNAVKYTPRGRAVTVRVVEHPDVVELAVADDGIGISEADQQRLFTEFFRSTNPDAVAQPGTGLGLTISARIVERHGGRIEVESELGEGSTFRVFLPRPDAA
>NZ_CP040695|3864361:3923810|3909392_3910934_-|WP_148240862.1|DBSCAN-SWA
MSSQGSRPGGDGRLTAALDPHDQGPQDACGVFGVWAPGEDVSKLTYFGLYALQHRGQESAGIAVSNGRQILVYKDMGLVSQVFDETTLASLKGHLAVGHARYSTTGASTWQNAQPTFRPTADGSIALGHNGNLINTHELREMVDALPGPDDELDLHTRPVEVSTNDTGLVTALLAHHPDTSLEQRALEVLPLLRGAFCFVWMNENTLYAARDPQGIRPLVLGRLDRGWVVASEDAALATIGASVVREVEPGEMIVIDENGLRSHRFAEPDRKGCVFEYVYLARPDATISGRSVHESRVEMGRQLAREFPVEADLVIPVPESGTPAAAGYAEESGIPFGQGFVKNAYVGRTFIQPSQTLRQLGIRLKLNALDHMIRGKRIVVVDDSIVRGNTQRAQVRMLREAGAAEVHVRISSPPVKWPCFYGIDFATRAELIANGLSPEEIAASIGADSLGYISLEGMVDSTKQAASQLCQACFTGEYPVELPDESLLGKHLLETSIASPTHGKALPVLNNP
>NZ_CP040695|3864361:3923810|3880373_3881102_+|WP_148240857.1|DBSCAN-SWA
MWGAFTFPVTTSRSRRPGPGNLVAARCPSRANAEIARTHPVGAPTLAPTPHPRRAHVFIRYVDEGLEQLVRRRLPLPEDVGDVSFDTPTSTWAAQLSRLTVNLFLYGLDRSSQPTRTAQARVDASGRAERRAPLPMVELDYLVSAWAGSPRDEHQLLSDVVSLFAGVPVLPLDLTHANLNSTVTLGFGSDPTMRPREIWQGVSGQLKACAVIRATVAADTWDWEDQAAAVERVSVLAAPKQI
>NZ_CP040695|3864361:3923810|3869784_3870240_-|WP_148240851.1|DBSCAN-SWA
MPASARADVVRRSSTTTPATPASPAAPPAGGSLLSSTAHLFGDAQAGVVRRLLDQGGPAMPSGSAPDFFGQGRESWELEHRGGSIQPAEDMTGWTSNDGYRGFAVNTADADAGNLPGDAMDALVDAVVERIEARVVDELERRGRRQDWGVF
>NZ_CP040695|3864361:3923810|3921160_3922858_-|WP_148240866.1|DBSCAN-SWA
MTSLVLGPLLRHVDEVSASIWVEVDGPARVRVTTEGGPSAEAASFAVHGHHYAMVCLDGLERGRRYPYVVTVDDEVVWPDPGSDLPPSVVPTLDHGKPLRLAYGSCRTSVGHDEKGNATHGVDALRAFALRMAGLTDAGADDPDRSHGDGPRWPDLVAFLGDQVYADETTKEMQAFIEQRRGLDSEPGDELKDYEEYAHLYRLAWSDPVNRWLLSTLPSLMIFDDHDIRDDWNTSRAWKDEMEATSWWHDRIVGGLASYWVYQHLGNMTPSERADDAIWSLVVEHADEPGFDVSDVLDAFADRADQEPTSYRWSFARDLGPQARLVVVDSRAARVLEDDERSILDDEELAWLDGQLRGDVDHLLVATSLPFLLAPGLHYVEAFSEALAGGGWGRRLTGLGEKIRQTVDLEHWAAFQKGFGEVARMTLEVGRGERGRAPATITFLSGDVHHSYLSAVKPLPGVRSRILQAVCSPIRNPLSRKWRFATAALSYGVAGPLGHVVARSAKVPDAPFSWRLVEGPWFDNNLAVLEVHGEGIRLWWATGKVEDDVDRPRLVRVSDVSIDCP
>NZ_CP040695|3864361:3923810|3920320_3921142_+|WP_148240865.1|DBSCAN-SWA
MPEGDSVHKLARRLDRSLLGRTVVRSDLRVPRLATRDLAGRRVLEHATHGKHLLTRFSGDVTLHSHLRMDGEWSVTGPGKQLPRRLQHEVRLVLVLDSGSTAWGLRLHDLALVATTDEASIIGHLGPDPLREDWDAAEAVRRLRTDPSLPLVSALLDQTRVAGLGNLWVNELAFLTGVSPWTPIGSVDVERLVARAATALRHSALVPGAYQVTTGSSRRGEDHWVAGRQRRPCLRCGTEVRMVAELANDPANRRTWWCPHCQPGPGPETRRPA
>NZ_CP040695|3864361:3923810|3898970_3900971_+|WP_137294524.1|DBSCAN-SWA
MSPTMGVQPAAPSRLTTSPRKQVTLSEQLVDEPVGTTDGSDAPPAYNPWQSVLWALRVSWLGAMACALVLELSGLVGEESYWWHSTFVDGLSYVLDSVVIWVILVAVIGLTNRVILSLGIVAAGTITLAAANRVKLGLRSEPVYPSDVDFLREPSFLLTQVSVGTLVVAGIGLVVLVAVAWLVGRRFEPRMPRIWPPHLSVRRQLVAVGVRAVLVTLAIGTIQNTANFNDPGNPLRGLYEVGDHEWKYWNQRNNYLANGFVGGFLSNMPTVAMKTPETYSEETMDALATRYERAAARINRKRTGTLDDANVVVVLSESFTDPTQLEGFELARDPIPKIRKVMREGSSGTMMAQLLGGGTANMEFETLTGESIGLFEPQLSTPYQMLVSDYDQYPSAVGWLGANGHKPIAVHPYLTSFYKRDKVYETLGFDEFIHDTTMTETERIDDNEFISDKSAFDEVARQIDDADEPLMVNLVTMQNHIPVDGNYDDPIPVTGVEGDQADRISNYARGLSHTDDAVADFLTRMKRSKERTVVVFYGDHQPGIYDSSIADQNPGLALYTTPFFLWDSAGTPKQQLPQSSPTQFLPMLYDMVGAPVPPYYVLLNRLRTYVSALEQGRMLSPEGQEITEDDLPPRGRRLLEDVRLVQYDFSIGDRYSVERMWPGSMR
>NZ_CP040695|3864361:3923810|3879492_3879885_-|WP_137294530.1|DBSCAN-SWA
MGNPAAVTGAMLTCTFGVAPSTLNVIPAKRVTVEGRPVATIPDIAPGVNIAPFGMCTSLTNPMVAAATAAALGVLTPMPCVPVVPAPWAPGAPRTLVGGLPAVTAGSMCTCAWGGVISITMPGAVRTSMG
>NZ_CP040695|3864361:3923810|3903044_3906347_+|WP_148240860.1|DBSCAN-SWA
MMSWMDGMRLGPDDALLRSMVDATPDSLWLLGTDGVTRYANQRLADLVGYPLDELLALSPLDLVDAQGREDLERHLEQMRAGHPGGENEEVRLTRRDGSSVWTLVSWAPVPGAPGTYLHRLTEYTERRRLLEELRLREEQLSTAGRMARLGGWTWDLRRNHVTWSDELFEILAVDPDSFGGSWEAGLSAFHPEDAEHGRTVILEALEHGDDFSWEGRVTTPDGAVHWIRNFGVLERDEAGAVVRATGTSQDITDLQAADHAAGEATRRVEMLQRLAAAANRSATVAEALTESDRVLRGVSRWRAIGYFATGPDATLVEGRLAHPGGPDLPPADVELAEVARRSRRLEMAPLPDRPGTGILSVPVVTDDEVVYVYQLLADTETPSAATLSLVAQSSDQLAWVAERERAAARLAQAHDDAMTASRMKSEFLAMMSHEIRTPMNGVIGLNDLLLGTALDDQQLRYAQGVRSAGLTLLALIDDVLDLSKVESGKLELEVTEFDLRALVDETVGLLAAPARVKGLDLVAGYGPGVPRTVLGDPVRLGQVIANLGSNAVKFTDAGTVVIEVTCPDPDEHDGHVVLQVEVRDTGVGIAPADVDGLFDAFTQADLSTTRKHGGTGLGLTISRRLVTTMQGEIGVRSTPGEGSVFWFTARLRAAPPGADTALPPLQPLHGLRVLVVDDNPTAAAFLARQLSEWGLSPVVVGSSTDAIATLAAAAADRTPFDLAVVELDLPGTDGLALGHRISLDPGLPDVALVLVAADGGVDPATAREAGFRTVTAKPVRVAALHEDLLDTVTDTVAATVTASVAVTGDDAGGAPARTRRQRPARAVRPGGTGLDLHVLVVEDNAVNQLVAIGVLENLGCTVVAVENGEEAVIALRPGHAFDVVLMDCRMPRLDGFGATRAVRAVETGHRVPIIAMTASALPGERDRCLDAGMDDFLTKPVDPVRLAVALARAVGTRTDAGHPETPVPAAGPPASADHDVLDVERVELLDELVKDGVSFFERGRMSFLARIDQSMEQIGRAVAERDVEGTVQGAHQLRGSALNLGLRRVGATAEDLEQAARDGSLDRADALLLALRHAVVIGVEALVGVDLPGRRPPTP
>NZ_CP040695|3864361:3923810|3883605_3886344_+|WP_137294526.1|DBSCAN-SWA
MHVDVSPRQFDVIAGIPQPIVVTLSNTGDVIGGYTLRVLGADPSWVGMDDAEITLFPDETRTVVVTLEVPPGMTAGDRRVALQVREVTPPFASIVEDVVLSVPEAPSVTVTADPVVVSAGRTAKLSILVANEGNTRVSGRMHGQDPEGRVRFEFSPGTVDLAPGENTMIDLRARSRRPLTGSPVIRPLELRMLDEAQSSALDRAQEEPVAAGVAADAGEPAPRPSAAQKLSPKLRRKRPPLVGDDVPAQAQATFVQRATISRGGLSLVGLLVAVTVFAIVITLSLGQLVGRSAEDRDLALAIAAAGDASATGGSAQVGGTVRLLTSSEPVEGVEVSVFAADDTESARGTIATDRNGAWKVADLPAGDYKFSFRGAGFVQLWYPTALDAADGQTVTVESGGQQLSLDVDLGGVPASISGTVVGADVSNATLTLKAPLDATNAGAGANAPIPADGVDNPSVDVASEGATVTSVPIGDDGTFSLTDVPSPQTYDLVVEKEGYATSTQRIDVSAGEEREDVEITLRQGDGVISGTVSSATQKVEGATITATVGQTSVTTTSQTGAQGGDFTLRGLPTPAAFTLVVSQEGYASQTLTVALGEGQRLTGVAVNLDKSSGELCGKVISVLDDLPAPDVTVTVTDGSQTVQTATQSDDSAGPACPTVPGTNWKASGLPLPGDYTITFARADLESQTVAVALDGEGNVSADAENSAVVNGVITVRLQASTAVVFGKVTQSPTRGVAAEPAGETVVQLISNTATYSVVAASVPAASAGDYRFDAVPPGTYTLQTSRSGVTPTTETLTVEAGQEYERNLKLDPPASLSGVITNARPGWVVELYRSSAYPSQTYLTTTVVMREIRGRGCPENMCAYYEFLDIDAPQTYVIQVRRTSGGAPLATARAEVNRSEPQTKDFQVRSDG
>NZ_CP040695|3864361:3923810|3866931_3867366_-|WP_137295306.1|DBSCAN-SWA
MSELTVPGGHGDETSFIGRGFGWPMGVDHTGSIRLSSGVPELDRSIEMVLMTAPGERLMRPQFGCRIWDLLFEPVTANLLGLINQAVRDALAQWEPRITVEEVTSTGDDSSSSLVNIHIGYRVRSTNDRRNLVYPFYVIPHDAE
>NZ_CP040695|3864361:3923810|3919002_3919452_+|WP_138876720.1|DBSCAN-SWA
MRLTAPEALHVQVEDPSAFAETYTRLQGEYPDARTWRVRGDRMATARAAFDELGAALQLPYYFGGNWAALEDCLLDLDWAPATDYLLLVCDAHLALADEPDQLPSLLGSLVRAHEAWQPRSFRTVLQVPAGADDALWSRLAQAGQATAV
>NZ_CP040695|3864361:3923810|3875252_3876824_-|WP_137294538.1|tail|DBSCAN-SWA
MPTYTAPGVYVEEVPSSQKILSAAPTAVAAFVGFTELAPTDDPNDPQGLAPRLVTSWTQFESLYGGFAPGCMLPLSVYGYFANGGSIAYICRVPNTEPAGEPATAALPAADRSLGLPVAVTSVEPDANIAVQVTSDDAGDDDDAQPTFTMTIIENGVAVEEFSGLSFDKGDSNVATKVNATSTKVKVDLDLAEDADVASQLELVKPGTYSLSKAAPIPVPVTGKKFAGSESARAGINGLAVAEDVTMVIVPDLVTAATKEDGSLDLGLWKAVQTALISHCEQNGNRMAVLDAPPGMNPQQVKEWRSETAMYDSAYAALYYPWVKVENPNPTNGETEILIPPSGHVAGVWARTDDTRGVWKAPANDTMRGVLDIERSVTQNEQSLLNPIGVNCIRPFGTRGIRIWGARTLASDTDWNYINVRRLFNMVESTILEGTQYAVFEPNDMALWEGVNRTVSGFLRGLWTAGALSGLSADEAFYVKCDAETNPPESVDAGMLVVEVGIAPVKPAEFVVFRISQKKQVAG
>NZ_CP040695|3864361:3923810|3908298_3909363_-|WP_138877233.1|DBSCAN-SWA
MTEQNAYARAGVDIEAADTAIELMRASVAKASRPEVIGGLGGFAGLFDATALTQYTRPLLATSTDGVGTKVAIAQAMDKHDTIGFDLVGMVVDDLVVCGAEPLFMTDYIATGRVVPERIAAIVKGIAEACVEAGCALVGGETAEHPGLLAPDEYDVAGAATGVVEADRLLGPGRVRPGDAVIAMASSGLHSNGYSLVRQVLLADAGWSLDRHVPELGRSLGEELLEPTTIYAKHCLALADQVELHAMSHVTGGGLAANLARVLPAELRASVERATWNPQPIFDVVRQVGSLSQADLEMTLNCGVGMIALCPPDSVEAALHLLDGLGVRAWVAGQVDVDPEQSATVRMVGQHPDW
>NZ_CP040695|3864361:3923810|3912869_3914303_-|WP_138876718.1|DBSCAN-SWA
MSVAPLQVPSRTQDPRSVHRTAIIGGGASGVLTAIQLLSSSDNPHLRVEIHEASGIVGRGIAYGTNDPHHLLNVRSRHMSAFADVPSDLIDWARATGRSQDPQAFLPRLDFATYLQDRLASVADYRLSIRAGRVDDVVPHTDRHGAGFDIHAQDVVTHADSVVLAYGNRRPQPLVIDGDALPAAPWHLADPWNLAGLRMLPDDATIVVVGTGLTAVDTVITLLEEGPGRRVVMVSRHGLLPHQHVAQLSTAWVQPVPEGPLTADLLAEHVTEQVAAAAAQGVGWRAVVDGLRAATPSLWKRLPIEERRRFLAVHAREWETRRHRMAPEVAERIRVYADDGRLSVLGGGLLSIADRGATCQVRIAGVATPLVAGAVVNCTGPSTDITRSDDPLLLALRERGLVRPDPLLLGIDTTDEGRLVGDDGTVAPGLFAVGPPRKGTLWESTAIPEIRGQAADVARGILGLTGARRVDTAAAPA
>NZ_CP040695|3864361:3923810|3922883_3923192_-|WP_137294510.1|DBSCAN-SWA
MRQQPKVEAQGGKAARVLYKPWGIVGSIVAALIARQVFTVVWTKVVPVDSEDPPKPLESEYSLGQVVLAATIQGAIFAVVKALFQRASARGFQRWTGEWPGD
>NZ_CP040695|3864361:3923810|3923188_3923398_-|WP_138876722.1|DBSCAN-SWA
MSDSNDPEAIQADIERTRADLAATVDQLTGRLQERKTQAKDLGVKVAAGGAAVLLLVVVVRVVRSRRSS
>NZ_CP040695|3864361:3923810|3923390_3923810_-|WP_137294508.1|holin|DBSCAN-SWA
MSHPQQPAGQPGEATSTGELISRLSDQSSQLIRDEIRLAQAETAQKVKHGVTGIAGFGVAGLLALYGVLGLLATAVLGLAEVLPAWLSALIVSVVVLAAAAVAALLGKKEMGEVGGVAPTRAVEGVKQDVDTLKGGHHE
>NZ_CP040695|3864361:3923810|3874192_3874720_-|WP_138877231.1|DBSCAN-SWA
MRTTYEFTLPRGYVDDEGTLHRKGVMRLATARDELAPLRDPTVQGPDDPRLTILVLTRVVTRLGSLEQINSYVIEGLFAVDLAFLQDFYGVINFGNQEEFDALIAAQESSALVGSSAPAPSSAPAAAPAAEGAGPGSADDATAPPAPAGPTGVSEQVSERPSLRHSVEELPRRSS
>NZ_CP040695|3864361:3923810|3907972_3908164_-|WP_137294520.1|DBSCAN-SWA
MGRGRAKAKQTKVARDLKYRTHETDFGALAKELHGGESDDVDPVDPVEEPDEWSGYAPDRSRD
>NZ_CP040695|3864361:3923810|3864945_3866898_-|WP_148240850.1|plate|DBSCAN-SWA
MPLPSPSLDDRTFQDIVDEAKRMIPRFCPEWTNHNVSDPGVALIELFAWMSEMVLYRVNQVPDRLYTHFLNMVGIEPFPPSVAGTNLTFWLSAVLESAVVVPASTEVMTVSTTSAAVDSVVFSTVAELVIAPPRLEHAKVSTAVEGTVTDVWDDLRFGTVGARVFASSTMAVGDTFCLGFRDSLAGMVLRLAVEAQAEGIGVDPRNPPIAWEVWNGEGWLATEVYEDTTGGLNRAGEIVLMVPVEHQPMSVGNQSAYWLRARLLPTANGRPTYQASPRVQRIEVSALGGTVRAEHAEEAPGEQVGRSDGGAAQRFSVTHRPVLPRRGDEVVRVVDGSEVQEWTEVADFSGSTPRDRHYVWNDSNGEIQFGPRVRYPDGSVRQHGDIPRDGAMIEVSGYRHGGGSRGNVGARTLTLLRSTVPFVSGVVNLLPATGGVDAESVEEAKVRGPLTLRTGQRAVTAQDYERLTLEASPAVARARCRSARRGNGTVQLLVVPEVRGEAGGHTIDDYAISAQLMATVTDHLDAHRVVGTAVEVTTPFYQGVSVVALVHGAPGRPQGIVKQRASEALARFVNPLIGGPDGAGWPFDADLNVATVTQLLESVEGVERVEEALLFEYDLRTGRRLGAAKDVIRLDRQSLFLSASHQVVVR
>NZ_CP040695|3864361:3923810|3873504_3873999_-|WP_137294545.1|tail|DBSCAN-SWA
MASSGGTGSPAEDPLGGDIPTANRFLFELDGVEIGVFRELYGLQVTVGVEEFREGGQNGFSHRVPGRMTWPNIVFKRGVTSSNALFEWLQKSSGEGFASSGNKLTRSTGAVTAIDHVGTRLRAWELIDVFPVRWKGPDFSVASQDALEEELEIAHHGFRAKTQA
>NZ_CP040695|3864361:3923810|3874725_3875205_-|WP_134766694.1|tail|DBSCAN-SWA
MPNESLIATDPIVAQNFYLEIAGENIILTGVSGLDVEADVVSIQQVGKTGRSEMVKTRGNINKAADITITRMAPMDAMSDPIWKWFKDIRDKGMGGTARTATRKDGSIVLYDGAYAEVGRFNFSKGWPSKIATDAVSTDSNEAVKETITLVIERLDRVK
>NZ_CP040695|3864361:3923810|3881315_3883604_+|WP_148240858.1|DBSCAN-SWA
MRLVTEHLVLQADPGTTIEIPVDVVNTSDLIDGVTARLIGLPDAATRIEPQLLPLFPGAEGRLVMHVDVPPSLTAGSHPVTVEVVSHGSGAPTQHLDLDLSVAAHPALRLHRTPQLIRARRSGRFLLDVENTGNTALDVTLAASLEDGRSTARFSSERLTVDPGTRTPVILVVKGPRMITGAEIDRTAAINLTASRAHSIAAMEETEQDPDLVAETRVVLKQRPTLSRGLLTALILMGIIAVWAAIFVLGLAQVLGGDPVTKKVATSFYPADRVENVAATTPEGALDKEDGLVDPEIGGTIQGVVTAASNLQPVGRILVQAWRDGRDGPVLVSSAATQADGSYRLVGLFPTSYRLRFVAAGYEPAWWSDRGAVGRGRATAVPVPAQGEAEGLQNIVITGLDASITGVVDQGASLTSLPTTVVARSLDIPDAPTVRTTTDGGGTYLLRGLLAPSRYELSFTTEGYEVKTTTTSVAGGEKRLQPSVVPASADGRITGRVELPDGTPAGGVTVTTTVEGETVAVVTPTVGAVGSFTLENLPTPATYVLTFTSETYGADTTIVDLDAGASEDGVVVQVEAGTTSVTGYLRGPDGNGLGGATVTVGGVAATEDGTTTPTTTTLTSGDVGRFSLSGLAAPGDYTLTFTLEGYAPRSVPVSLDGVSPPPVVEVQLNNKLGGIAGQVYGATDNPYVGAQVTITNGLTTWTATSGGAGSIDGNGGYRVEGLPSGTYSVTVTAEGLRQQTAMVVVMEGLTSFQDLALGSGGG
>NZ_CP040695|3864361:3923810|3870594_3870906_+|WP_148240852.1|DBSCAN-SWA
MDAADVVPGAEPPVVPGVVRTAEPRLRTDAADGAEARATWRRIDSGADAARPARPARPPAAPTRRGSGSEALAVAGRMSSAVPSAVASGWPASTPCRVERRTE
>NZ_CP040695|3864361:3923810|3877044_3878085_+|WP_148240854.1|DBSCAN-SWA
MTATAGSWGPADLPAISPARAERYALRPGEVPQLSAYAAASSALGLRARIVLLSGRGIGPTQVARVLGVSRQTVHTWRTRYADAGLAGLHDQPPKPVRAADDRAIVAATLAPPPASVGATTWSARSLAAHLGVGHSTVARAWEAQGVRPNGADTFRVATTPELVVQLVEVVGLVLARDVRLVALLVRDATATGATRHARTRSPRTGLAPLYLYAATRAALADPAAHARRGRLDLGRWLDGLEGSGTDGARLCLVADTGDVLARPALAAWLSARPHVRTHHAGSTRRWLRLTTAFLTLAESRTTGPGCAPEMAGLLRGLTSGDLVLPAPLVWSGPGARVPVPAPPRR
>NZ_CP040695|3864361:3923810|3864361_3864949_-|WP_137295304.1|tail|DBSCAN-SWA
MSALVKVSSAGLTRPRKPRRPDDWMLRQLPVQMLSHDFFVRFVSIFQELGSTLLEDADGVEHAVDLTIAPESSIAWLGSWIGVDKLDNSMPEALRRRIVATAARTLATRGTVAGLTSYLELLSGSTAEVVEGGGIWRAGEVPDDTAWVRMRVQRTGSLDEAAFVDMVRDEIPAHVTAELWVADRQVWNSEQDEEW
>NZ_CP040695|3864361:3923810|3916774_3917134_-|WP_138876719.1|DBSCAN-SWA
MAARLRPADPALVREATERLASGSHERADLKLLVKHYLAVLEDRAPGRSVEVRVPPYAAVQVIEGVRHTRGTPPAVVETDALTWIALATGALAWIDALTHARASASGERTDLTPYLPLT
>NZ_CP040695|3864361:3923810|3906684_3907806_+|WP_148240861.1|DBSCAN-SWA
MSVTSSVTSVTSSPPSLPADVFELGAEHEQVVFCQDAATGLRAIVAIHSTALGPALGGTRFHPYATTADALADVLDLSRGMSYKAALGGLDLGGGKAVIIGDPATLKSEALLRAYGRFVESLSGRYLTACDVGTYSEDMDHVARESRHVTGRTVAHGGAGDSSVLTAYGVFRGLLAAAEAAWGTDSLEGRVVGVSGVGKVGRHLVGHLVEAGASVVVTDVSDQALDRVRDEHAGVRVAESTEALVASPLDVYAPCALGHALTDEVVEVLSARVVCGAANNQLAHPGVEKALADRGVVYAPDYCVNAGGLIQVADELEGFSFARAQQRAARIYDTTRAVLELAASDGVPPATAADRLAERRMREVGRLRGIWLG
>NZ_CP040695|3864361:3923810|3870957_3872850_+|WP_148240853.1|DBSCAN-SWA
MVGAVTGTAAGAAGAGAAAAGTTSAGVPAGVPPWVAGVGTAASTLRRTTVADPAEKPASAAVTPATTGACRPTTAERRTSAAGAMTWSVLHRRRTGRRVLRASPGAAAEAASPGAVWIGAIGGGADPLGSPAAGAGPEAAAAWAAGVAGVAGVAPSIRRRTPPGLRPTATVDVVGTAAGAAGTAAAGRPCCWAPGDAGAGGAVVEDPAAGATAGATAGEAVARTCDGAGDEEGEATGATSAEAIDAGDDAAVAVERRTVPPAWRITGLDAVQRSRRAAAAPAAAPAPVAGAAWERAMRPGPAARTASPSRTALSSPRCWAEGNAVAAATGTPPLPVVLPGTVAADAAGAGARGVVPAEVGRLGVDAAASPGAVERERAPALLSAMPAERPDCRITRLPADHTSRRETPGGVAERRIRDGADAASVRASRTPLSSAARPAASGAEAAVCVAAVAGVRRTIVPNRPGPEPSCHDARRTGPAAEEGAAEAEDEETGDEADDAGVDTAAPDGPLTGADGGLGVPGPEPPEEPPDGPAGGPPDGPADGPGGAAGPSPGSGPSARGGLVGVALAAAVDGVRRTGGAGSGGGATTRRVAWSRERSPGVSIGPAAWTSTCRRTWATWAVRPPTMPPGV
>NZ_CP040695|3864361:3923810|3918493_3919006_+|WP_138877234.1|DBSCAN-SWA
MAHTTPDDLDQITQRCRDTKVLLRIYRAARLDGARVVKWLVTSARHDAADLDAYLARGGRAWLDETCGPPALPAGVTKEDIVRDAQPKEGSARPPTNGFAGNRRFTNQGKLPDMLLPARTAENKAITYREYDVQRYRPGVDRGSRRFVKGSDGRFYYTDDHYQTFRKFAP
>NZ_CP040695|3864361:3923810|3901006_3902308_+|WP_138876715.1|DBSCAN-SWA
MPASLPAFRTAARLRPVDVVQPGSRVGPAPFVAAERDLAAGRPAPADVVLRSGRTTFRATWDGAVVALEVGDATGGVSRHVSRRHGHGVSPTTLALALTGPYLAAFVREAGTWVARAVVDLTLLPGAPDVHDEDWLAGLSAEGERTGTFGQLGFRDVRTVTHADGTAHLDGDRVLLTATSAGPGGFRTGHTSVWALDPLRLEVEHRADLFFRRPERPGTFGDHATHLVRDGDRWLVATSTWGDFDKRTNPRVTTTLATETADVDLLHGHHVLDTVPLDLPVEGLDSVGRWDPHLVRADGGWLATYVSARRFFSFHPVLAQGRDLDRLRLRAAATDRTATEGPTLTRLGEEWAVLASDGRDNPRGRRAAYPVYDLDLRQRGTLDADYPTNIPWPTLVPRPGGPAVVGFDGTPAGGPLLDYGTHGDLVVQLPVVP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_137295304.1|3864361_3864949_-|tail	phage tail protein	NA	NA	NA	NA
WP_148240850.1|3864945_3866898_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_137295306.1|3866931_3867366_-	GPW/gp25 family protein	R9TRM1	Vibrio_phage	9.5e-06	39.7
WP_138876701.1|3867365_3869129_-	hypothetical protein	NA	NA	NA	NA
WP_138876702.1|3869128_3869785_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_148240851.1|3869784_3870240_-	hypothetical protein	NA	NA	NA	NA
WP_148240852.1|3870594_3870906_+	hypothetical protein	NA	NA	NA	NA
WP_148240853.1|3870957_3872850_+	hypothetical protein	NA	NA	NA	NA
WP_137294545.1|3873504_3873999_-|tail	phage tail protein	NA	NA	NA	NA
WP_138877231.1|3874192_3874720_-	hypothetical protein	NA	NA	NA	NA
WP_134766694.1|3874725_3875205_-|tail	phage tail protein	NA	NA	NA	NA
WP_137294538.1|3875252_3876824_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.3e-68	34.4
WP_148240854.1|3877044_3878085_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148240855.1|3878196_3879414_+	DUF222 domain-containing protein	NA	NA	NA	NA
WP_137294530.1|3879492_3879885_-	DUF4280 domain-containing protein	NA	NA	NA	NA
WP_148240856.1|3879907_3880549_-	hypothetical protein	NA	NA	NA	NA
WP_148240857.1|3880373_3881102_+	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_148240858.1|3881315_3883604_+	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_137294526.1|3883605_3886344_+	hypothetical protein	NA	NA	NA	NA
WP_148240859.1|3886336_3892564_+	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_137294524.1|3898970_3900971_+	LTA synthase family protein	NA	NA	NA	NA
WP_138876715.1|3901006_3902308_+	hypothetical protein	NA	NA	NA	NA
WP_134766683.1|3902660_3902939_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.4e-18	59.6
WP_148240860.1|3903044_3906347_+	response regulator	A0A1V0SGX0	Hokovirus	1.4e-48	29.3
WP_148240861.1|3906684_3907806_+	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_137294520.1|3907972_3908164_-	DUF3073 domain-containing protein	NA	NA	NA	NA
WP_138877233.1|3908298_3909363_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.2e-56	38.4
WP_148240862.1|3909392_3910934_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.4e-48	30.1
WP_148240863.1|3911008_3912847_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	9.6e-15	27.3
WP_138876718.1|3912869_3914303_-	SidA/IucD/PvdA family monooxygenase	NA	NA	NA	NA
WP_137294517.1|3914390_3915740_-	dipeptidase	NA	NA	NA	NA
WP_148240864.1|3916186_3916771_+	hypothetical protein	NA	NA	NA	NA
WP_138876719.1|3916774_3917134_-	hypothetical protein	NA	NA	NA	NA
WP_138877234.1|3918493_3919006_+	hypothetical protein	NA	NA	NA	NA
WP_138876720.1|3919002_3919452_+	barstar family protein	NA	NA	NA	NA
WP_138876721.1|3919461_3920310_+	hypothetical protein	NA	NA	NA	NA
WP_148240865.1|3920320_3921142_+	Fpg/Nei family DNA glycosylase	NA	NA	NA	NA
WP_148240866.1|3921160_3922858_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_137294510.1|3922883_3923192_-	DUF4235 domain-containing protein	NA	NA	NA	NA
WP_138876722.1|3923188_3923398_-	DUF3618 domain-containing protein	NA	NA	NA	NA
WP_137294508.1|3923390_3923810_-|holin	phage holin family protein	NA	NA	NA	NA