CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	1 crisprs	NA	0	4	0
NZ_CP030042	Enterococcus faecalis strain C25 chromosome, complete genome	3 crisprs	csa3,DEDDh,DinG,cas3,cas14j,WYL	1	4	7
NZ_CP030044	Enterococcus faecalis strain C25 plasmid pC25-2, complete sequence	0 crisprs	RT	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP030042_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030042_1

192653-192726

Orphan

Consensus_repeat	Method
GTTTTTCTGTTGCTCACCAACTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030042_1

>merge|NZ_CP030042|1|192653-192726|CRISPRCasFinder
GTTTTTCTGTTGCTCACCAACTATTGGCTCTACGTCCAATTCTATATCGAGTTTTTCTGTTGCTCGCCAACTAT

>NZ_CP030042|1|1|192653-192726|CRISPRCasFinder
GTTTTTCTGTTGCTCACCAACTAT	TGGCTCTACGTCCAATTCTATATCGA
GTTTTTCTGTTGCTCGCCAACTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030042.1\|WP_002354864.1\|183084_183882_+\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NZ_CP030042.1\|WP_002398179.1\|197830_198529_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP030042.1\|WP_002354871.1\|189794_190232_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP030042.1\|WP_002398178.1\|198623_199340_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP030042.1\|WP_002398175.1\|203939_204194_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030042.1\|WP_002354869.1\|189107_189662_+\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NZ_CP030042.1\|WP_002354863.1\|181368_182925_+\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NZ_CP030042.1\|WP_002381060.1\|190406_191378_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP030042.1\|WP_002398183.1\|191992_192586_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376232
NZ_CP030042.1\|WP_025189669.1\|193712_196457_-\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NZ_CP030042.1\|WP_002359008.1\|183955_184342_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226923
NZ_CP030042.1\|WP_002360992.1\|202771_203638_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NZ_CP030042.1\|WP_002398185.1\|184342_186919_+\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_CP030042.1\|WP_002354883.1\|199380_199830_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP030042.1\|WP_002392696.1\|191609_191753_+\|putative-holin-like-toxin	unknown	unknown	gnl\|CDD\|319017
NZ_CP030042.1\|WP_002380969.1\|201299_202604_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP030042.1\|WP_010716772.1\|186950_189083_+\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NZ_CP030042.1\|WP_002398177.1\|200038_201307_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP030042.1\|WP_002367455.1\|196717_197431_+\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_CP030042.1\|WP_002398182.1\|193047_193698_-\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672

Protein	Function_ID	Function_description	E-value
NZ_CP030042.1\|WP_002354864.1\|183084_183882_+\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.68643e-155
NZ_CP030042.1\|WP_002398179.1\|197830_198529_+\|hypothetical-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	7.45601e-10
NZ_CP030042.1\|WP_002354871.1\|189794_190232_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.48715e-93
NZ_CP030042.1\|WP_002398178.1\|198623_199340_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	2.41264e-24
NZ_CP030042.1\|WP_002354869.1\|189107_189662_+\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	1.6551e-85
NZ_CP030042.1\|WP_002354863.1\|181368_182925_+\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NZ_CP030042.1\|WP_002381060.1\|190406_191378_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP030042.1\|WP_002398183.1\|191992_192586_-\|hypothetical-protein	gnl\|CDD\|376232	pfam18813, PBECR4, phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4. A predicted endoRNase of the Barnase-EndoU-ColicinE5/D-RelE like nuclease fold found in polyvalent proteins of phages and conjugative elements. The predicted active site contains a conserved histidine residue.	1.89421e-23
NZ_CP030042.1\|WP_025189669.1\|193712_196457_-\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	9.76019e-174
NZ_CP030042.1\|WP_002359008.1\|183955_184342_+\|hypothetical-protein	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	2.38925e-14
NZ_CP030042.1\|WP_002360992.1\|202771_203638_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	8.53832e-35
NZ_CP030042.1\|WP_002398185.1\|184342_186919_+\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_CP030042.1\|WP_002354883.1\|199380_199830_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NZ_CP030042.1\|WP_002392696.1\|191609_191753_+\|putative-holin-like-toxin	gnl\|CDD\|319017	pfam16935, Hol_Tox, Putative Holin-like Toxin (Hol-Tox). Hol_Tox is a family of small proteins (34-48aas) with a single TM region. Members can exhibit antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria.	3.57939e-12
NZ_CP030042.1\|WP_002380969.1\|201299_202604_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	6.66379e-85
NZ_CP030042.1\|WP_010716772.1\|186950_189083_+\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0
NZ_CP030042.1\|WP_002398177.1\|200038_201307_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.75552e-51
NZ_CP030042.1\|WP_002367455.1\|196717_197431_+\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	2.26478e-136
NZ_CP030042.1\|WP_002398182.1\|193047_193698_-\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	1.9434e-106

>NZ_CP030042.1|WP_002398183.1|191992_192586_-|hypothetical-protein
MIEKKDFDTIRKAFLIYDTNFNNHMFTYTYQHRKTKKLLEMNVQFEAGNFMHLCGVDYYQIDKQGSCKFRFKATQFYRALKNNKVSLRGIKPKDDGTTGQKLQVIPLLEMLISPGVRVCDGGKFYNLQYEKAIRSGKMIVALTCKENNKNYVPQSLLSLINQPRKSQSKSLTESHEVIKISKSELNSTSVIEVYDKF
>NZ_CP030042.1|WP_002392696.1|191609_191753_+|putative-holin-like-toxin
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
>NZ_CP030042.1|WP_002381060.1|190406_191378_+|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIAKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NZ_CP030042.1|WP_002354871.1|189794_190232_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NZ_CP030042.1|WP_002354869.1|189107_189662_+|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPTFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NZ_CP030042.1|WP_010716772.1|186950_189083_+|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPEAVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAADSANHWETASNEQQVIAEETKITEVPDSEPSLRSSEAADEVFQEEMKLHPEFDANSAASQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMISCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NZ_CP030042.1|WP_002398185.1|184342_186919_+|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKARQEMVQSLLNAYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVVLIATAINEEAPLQITEGNVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPSSVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NZ_CP030042.1|WP_002359008.1|183955_184342_+|hypothetical-protein
MKVKKMEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NZ_CP030042.1|WP_002354864.1|183084_183882_+|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFPEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NZ_CP030042.1|WP_002354863.1|181368_182925_+|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK
>NZ_CP030042.1|WP_002398182.1|193047_193698_-|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGIPIDETFNETLKGINRMDSLDRILVHGHRENAFTPAEKEALAQQKNDHYVQLLEQLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSIDALLNC
>NZ_CP030042.1|WP_025189669.1|193712_196457_-|glycoside-hydrolase-family-65-protein
MSIQVYKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLIVAEAAPILGGIVADFPADFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQAAAPNLLEAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETALITGDFFEKEAIMIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPKDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTTSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWAAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQSLAFQLIHQGVTYQFSLTQTSVTITADKDTQLLVQGALIPLTAERPKEVHYQ
>NZ_CP030042.1|WP_002367455.1|196717_197431_+|trehalose-operon-repressor
MNKFHDIFLELEQQIVQGDYQPGDLLPSENQLVETYNVSRETIRKALNLLINAGYIQKKQGKGSIVLNFKKFNFPISGVTSYKELQQTQHIESHTHVVSLEEIPVERNLAQLTGWREGAPVWRLVRQREIEGEVDILDIDYLIKEIVPELPKHRAEDSIFDYLENDLGLAISYAQKEITVEPLTEMDKQLIGEVEGNHVVVVRSIMNLEDTRCFGYTESRHRLNKFKFVEFARRRKL
>NZ_CP030042.1|WP_002398179.1|197830_198529_+|hypothetical-protein
MKKKMMASLLVGSAVVGASLAPLSAQATTTGNTPVQVEFGGGLLPDQEDNTGGSVDPDPTKPNTDFDLLAIPKSFDFPLAKIGEDLSALKESSSMVKSVMVGDVRGTKEGWHVTGEIAEMSNGTDKLDGQFNFGMTPFYAIFNTETGSYGGFNTLNGMDIANDPTAPTFSGTSMKIGGGATPLASATVGKGQGTWTGRFDNLTLNVTTPYQQIKAGAYTGSITWNLVAGPSI
>NZ_CP030042.1|WP_002398178.1|198623_199340_+|WxL-domain-containing-protein
MKKKMIASLLVGSAVVGASLAPLSAQATTTGNTPVTAEFEGGTLPDGNGDANTVDPDPNGSNSNFDLLFIPREFNFGKLSISDDLTKPILNQRDPEATNGHTEMIGVGDVRGGKEGWHLTAQSNGLKLGTESLQGNIKVALITQLDLEYEATSNSYVALTTAVSAPEVRPQLAAPQNWTLDLGGEAQLMANAAAGQGQGLWQFSLFNTALNITTPANNIKAGAYTGSITWNLVAGPSV
>NZ_CP030042.1|WP_002354883.1|199380_199830_-|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NZ_CP030042.1|WP_002398177.1|200038_201307_+|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAEETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKISELEIEQTKAMLKNQYILALDNAGAWLEKEYLNELMPQTMLTAEEWIARINAVTIPEIQEVAKRLELQAIFFLEGETEND
>NZ_CP030042.1|WP_002380969.1|201299_202604_+|insulinase-family-protein
MIKKDYAQIKETLYTETLANGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWRLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMAVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETFIREEGLSRFYMYPKGETEQ
>NZ_CP030042.1|WP_002360992.1|202771_203638_+|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSASVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETETTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NZ_CP030042.1|WP_002398175.1|203939_204194_+|hypothetical-protein
MVKIASNQGTAQKAIAGIKNVSVSKNQTCHLGESNISSMKKGVKVSNQLLNQLAKVVNGVNAQANKFPKLAATIAARDSQTTFK

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Crispr_ID: NZ_CP030042_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030042_2

810847-810974

Orphan

Consensus_repeat	Method
TGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAGATGTGGAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030042_2

>merge|NZ_CP030042|2|810847-810974|CRISPRCasFinder
TGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAGATGTGGAACAGCACAAGGTGACCAAAGGGAACGTTGTCTCCTCTGTGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAAATGTGGAAC

>NZ_CP030042|2|2|810847-810974|CRISPRCasFinder
TGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAGATGTGGAAC	AGCACAAGGTGACCAAAGGGAACGTTGTCTCCTCTG
TGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAAATGTGGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030042.1\|WP_010706545.1\|811097_812006_+\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NZ_CP030042.1\|WP_002356741.1\|804005_804455_+\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP030042.1\|WP_002398033.1\|809701_810490_+\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NZ_CP030042.1\|WP_002356760.1\|818145_819027_+\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP030042.1\|WP_002389231.1\|804637_805612_+\|phosphate-starvation-inducible-protein-PhoH	unknown	unknown	gnl\|CDD\|224616
NZ_CP030042.1\|WP_002356759.1\|817254_818040_+\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP030042.1\|WP_002356755.1\|814356_815289_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NZ_CP030042.1\|WP_002356753.1\|814131_814323_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_CP030042.1\|WP_002356744.1\|805640_807839_+\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
NZ_CP030042.1\|WP_002356757.1\|815837_816614_+\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NZ_CP030042.1\|WP_002356756.1\|815455_815731_-\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
NZ_CP030042.1\|WP_002367049.1\|816633_817071_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP030042.1\|WP_002356745.1\|807838_808318_+\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CP030042.1\|WP_002376733.1\|812007_814092_+\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_CP030042.1\|WP_002356740.1\|803803_803980_+\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP030042.1\|WP_002356761.1\|819287_820010_+\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NZ_CP030042.1\|WP_002382760.1\|802241_803099_-\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NZ_CP030042.1\|WP_002356746.1\|808295_808703_+\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
NZ_CP030042.1\|WP_002359745.1\|808716_809619_+\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CP030042.1\|WP_002387080.1\|803197_803638_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478

Protein	Function_ID	Function_description	E-value
NZ_CP030042.1\|WP_010706545.1\|811097_812006_+\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP030042.1\|WP_002356741.1\|804005_804455_+\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63
NZ_CP030042.1\|WP_002398033.1\|809701_810490_+\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.72495e-71
NZ_CP030042.1\|WP_002356760.1\|818145_819027_+\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.02636e-146
NZ_CP030042.1\|WP_002389231.1\|804637_805612_+\|phosphate-starvation-inducible-protein-PhoH	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	4.35931e-144
NZ_CP030042.1\|WP_002356759.1\|817254_818040_+\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	3.78425e-167
NZ_CP030042.1\|WP_002356755.1\|814356_815289_-\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	1.42463e-134
NZ_CP030042.1\|WP_002356753.1\|814131_814323_+\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	6.66934e-06
NZ_CP030042.1\|WP_002356744.1\|805640_807839_+\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	6.87785e-159
NZ_CP030042.1\|WP_002356757.1\|815837_816614_+\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	9.03482e-72
NZ_CP030042.1\|WP_002356756.1\|815455_815731_-\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	1.58992e-26
NZ_CP030042.1\|WP_002367049.1\|816633_817071_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.03251e-32
NZ_CP030042.1\|WP_002356745.1\|807838_808318_+\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	4.17563e-61
NZ_CP030042.1\|WP_002376733.1\|812007_814092_+\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CP030042.1\|WP_002356740.1\|803803_803980_+\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
NZ_CP030042.1\|WP_002356761.1\|819287_820010_+\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.02758e-148
NZ_CP030042.1\|WP_002382760.1\|802241_803099_-\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	4.76001e-139
NZ_CP030042.1\|WP_002356746.1\|808295_808703_+\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	2.85033e-42
NZ_CP030042.1\|WP_002359745.1\|808716_809619_+\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	0
NZ_CP030042.1\|WP_002387080.1\|803197_803638_+\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	4.90593e-35

>NZ_CP030042.1|WP_002398033.1|809701_810490_+|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLMPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSKYSGVLCEKHWHLDEQRYHADPRAIHFIRLFSQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEK
>NZ_CP030042.1|WP_002359745.1|808716_809619_+|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>NZ_CP030042.1|WP_002356746.1|808295_808703_+|diacylglycerol-kinase-family-protein
MRMALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>NZ_CP030042.1|WP_002356745.1|807838_808318_+|rRNA-maturation-RNase-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGEDELPIIFDDEELAELPRNLGDLIISTERAAEQAVEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>NZ_CP030042.1|WP_002356744.1|805640_807839_+|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVTFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRKRMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICASAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>NZ_CP030042.1|WP_002389231.1|804637_805612_+|phosphate-starvation-inducible-protein-PhoH
MTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>NZ_CP030042.1|WP_002356741.1|804005_804455_+|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>NZ_CP030042.1|WP_002356740.1|803803_803980_+|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>NZ_CP030042.1|WP_002387080.1|803197_803638_+|transcriptional-repressor
MAMAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK
>NZ_CP030042.1|WP_002382760.1|802241_803099_-|kinase/pyrophosphorylase
MTISEEKKCVTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETSED
>NZ_CP030042.1|WP_010706545.1|811097_812006_+|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQHVSKEAE
>NZ_CP030042.1|WP_002376733.1|812007_814092_+|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTPSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVIPFKVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFDVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKLFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>NZ_CP030042.1|WP_002356753.1|814131_814323_+|hypothetical-protein
MLETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>NZ_CP030042.1|WP_002356755.1|814356_815289_-|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQKIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNKGRNAGKQKRK
>NZ_CP030042.1|WP_002356756.1|815455_815731_-|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVKNEDDGSVSITAIAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>NZ_CP030042.1|WP_002356757.1|815837_816614_+|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLVEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFENNQ
>NZ_CP030042.1|WP_002367049.1|816633_817071_+|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEGQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDLLSLAVYRKNQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>NZ_CP030042.1|WP_002356759.1|817254_818040_+|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>NZ_CP030042.1|WP_002356760.1|818145_819027_+|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGEVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>NZ_CP030042.1|WP_002356761.1|819287_820010_+|UMP-kinase
MVKPKYQRVVLKLSGEALAGEDGFGIKPPVIKEIVQEIKEVHELGIEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENLGVPTRVQTSIEMRQIAEPYIRRRAERHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEVDADVILMAKNNVDGVYSADPRVDETATKFEELTHLDVISKGLQVMDSTASSLSMDNDIPLVVFNLNEAGNIRRAILGENIGTTVRGK

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Crispr_ID: NZ_CP030042_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030042_3

1046439-1046738

Orphan

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CRT

4 spacers

The CRISPR arrays of NZ_CP030042_3

>merge|NZ_CP030042|3|1046439-1046738|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACCTGCTCTATATAAAGGATATTATTTGGCTTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACGAAAAAATCAAAGAAAAAGCGGCAGAAGTTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTCTAGAAGAATATAGAGCTACTAAAAACAAGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACACCAGAAAGAGTTTTACGATACTATGATGAGTTTTATAGCCATGTTGTTAAAAAATAAACTATCAC

>NZ_CP030042|3|1|1046439-1046672|PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTGCTCTATATAAAGGATATTATTTGGCTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	GAAAAAATCAAAGAAAAAGCGGCAGAAGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TCTAGAAGAATATAGAGCTACTAAAAACAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC

>NZ_CP030042|3|3|1046439-1046738|CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTGCTCTATATAAAGGATATTATTTGGCTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	GAAAAAATCAAAGAAAAAGCGGCAGAAGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TCTAGAAGAATATAGAGCTACTAAAAACAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	ACCAGAAAGAGTTTTACGATACTATGATGA
GTTTTATAGCCATGTTGTTAAAAAATAAACTATCAC

>NZ_CP030042|3|1|1046439-1046672|CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CTGCTCTATATAAAGGATATTATTTGGCTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	GAAAAAATCAAAGAAAAAGCGGCAGAAGTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TCTAGAAGAATATAGAGCTACTAAAAACAA
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030042.1\|WP_002364252.1\|1042087_1042657_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP030042.1\|WP_002360016.1\|1054255_1055161_+\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP030042.1\|WP_002381711.1\|1060086_1060836_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP030042.1\|WP_002364369.1\|1049577_1051311_+\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NZ_CP030042.1\|WP_002398073.1\|1045416_1046280_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214874
NZ_CP030042.1\|WP_002356959.1\|1038310_1038655_+\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP030042.1\|WP_002360015.1\|1053153_1054134_-\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP030042.1\|WP_002356962.1\|1040184_1041423_-\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP030042.1\|WP_002364246.1\|1051307_1053074_+\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP030042.1\|WP_002356974.1\|1047144_1048563_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP030042.1\|WP_002398071.1\|1038880_1040005_+\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP030042.1\|WP_002364367.1\|1056714_1059138_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP030042.1\|WP_002362072.1\|1043250_1045332_+\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP030042.1\|WP_002356983.1\|1059267_1059969_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP030042.1\|WP_002360017.1\|1055189_1056401_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP030042.1\|WP_002356958.1\|1037097_1038243_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP030042.1\|WP_002356966.1\|1042754_1043120_+\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_CP030042.1\|WP_002425753.1\|1041439_1041955_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP030042.1\|WP_002356976.1\|1048559_1049573_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP030042.1\|WP_002356957.1\|1035966_1036941_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039

Protein	Function_ID	Function_description	E-value
NZ_CP030042.1\|WP_002364252.1\|1042087_1042657_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	3.60546e-15
NZ_CP030042.1\|WP_002360016.1\|1054255_1055161_+\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_CP030042.1\|WP_002381711.1\|1060086_1060836_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.63593e-110
NZ_CP030042.1\|WP_002364369.1\|1049577_1051311_+\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NZ_CP030042.1\|WP_002398073.1\|1045416_1046280_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|214874	smart00871, AraC_E_bind, Bacterial transcription activator, effector binding domain. This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.	4.05987e-27
NZ_CP030042.1\|WP_002356959.1\|1038310_1038655_+\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_CP030042.1\|WP_002360015.1\|1053153_1054134_-\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
NZ_CP030042.1\|WP_002356962.1\|1040184_1041423_-\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.18762e-174
NZ_CP030042.1\|WP_002364246.1\|1051307_1053074_+\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP030042.1\|WP_002356974.1\|1047144_1048563_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP030042.1\|WP_002398071.1\|1038880_1040005_+\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP030042.1\|WP_002364367.1\|1056714_1059138_+\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	7.68936e-175
NZ_CP030042.1\|WP_002362072.1\|1043250_1045332_+\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP030042.1\|WP_002356983.1\|1059267_1059969_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	5.36718e-38
NZ_CP030042.1\|WP_002360017.1\|1055189_1056401_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.24993e-121
NZ_CP030042.1\|WP_002356958.1\|1037097_1038243_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	4.17386e-179
NZ_CP030042.1\|WP_002356966.1\|1042754_1043120_+\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_CP030042.1\|WP_002425753.1\|1041439_1041955_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	9.06062e-31
NZ_CP030042.1\|WP_002356976.1\|1048559_1049573_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
NZ_CP030042.1\|WP_002356957.1\|1035966_1036941_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0

>NZ_CP030042.1|WP_002398073.1|1045416_1046280_+|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFIAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWSGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELAQRITPQQRAEMHTFDDVYPYQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_CP030042.1|WP_002362072.1|1043250_1045332_+|DNA-topoisomerase-III
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLSVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_CP030042.1|WP_002356966.1|1042754_1043120_+|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_CP030042.1|WP_002364252.1|1042087_1042657_+|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAR
>NZ_CP030042.1|WP_002425753.1|1041439_1041955_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHIYTLYVYATKNPLNLKEGFFANELHQALNDQRLAKAKFEFLY
>NZ_CP030042.1|WP_002356962.1|1040184_1041423_-|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLINLLWVRRSTAELKKEKNDD
>NZ_CP030042.1|WP_002398071.1|1038880_1040005_+|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDLAYQDEKELQYV
>NZ_CP030042.1|WP_002356959.1|1038310_1038655_+|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_CP030042.1|WP_002356958.1|1037097_1038243_+|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGVPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_CP030042.1|WP_002356957.1|1035966_1036941_+|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTTDRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE
>NZ_CP030042.1|WP_002356974.1|1047144_1048563_+|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_CP030042.1|WP_002356976.1|1048559_1049573_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_CP030042.1|WP_002364369.1|1049577_1051311_+|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_CP030042.1|WP_002364246.1|1051307_1053074_+|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVAQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_CP030042.1|WP_002360015.1|1053153_1054134_-|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_CP030042.1|WP_002360016.1|1054255_1055161_+|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_CP030042.1|WP_002360017.1|1055189_1056401_+|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_CP030042.1|WP_002364367.1|1056714_1059138_+|DNA-translocase-FtsK
MAQKRATNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAATETPEQ
>NZ_CP030042.1|WP_002356983.1|1059267_1059969_+|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEEMFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NZ_CP030042.1|WP_002381711.1|1060086_1060836_+|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQSFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIVQNGNQKEFYDLIMVKLAEIEGVDNEF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NZ_CP030044.1	67167-67196	0	1.0

1. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to position: 67167-67196, mismatch: 0, identity: 1.0

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagaatatagagctactaaaaacaa	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	MT119360	Enterococcus phage nattely, complete genome	70749-70778	0	1.0
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NZ_CP022485	Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence	14606-14635	0	1.0
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NZ_AP018540	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-2, complete sequence	73628-73657	0	1.0
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NZ_CP030044	Enterococcus faecalis strain C25 plasmid pC25-2, complete sequence	67167-67196	0	1.0
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NC_004670	Enterococcus faecalis V583 plasmid pTEF3, complete sequence	12025-12054	1	0.967
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	76144-76173	1	0.967
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	121698-121727	2	0.933
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NZ_CP053900	Proteus mirabilis strain YPM35 plasmid pJPM35-2, complete sequence	27198-27227	6	0.8
NZ_CP030042_3	3.4\|1046673\|30\|NZ_CP030042\|CRISPRCasFinder	1046673-1046702	30	NC_011774	Bacillus cereus G9842 plasmid pG9842_140, complete sequence	45872-45901	6	0.8
NZ_CP030042_3	3.1\|1046475\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046475-1046504	30	NC_014249	'Nostoc azollae' 0708 plasmid pAzo01, complete sequence	15166-15195	7	0.767
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	NC_014754	Sulfuricurvum kujiense DSM 16994 plasmid pSULKU01, complete sequence	117138-117167	7	0.767
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	NC_020522	Legionella pneumophila subsp. pneumophila LPE509 plasmid, complete sequence	13814-13843	7	0.767
NZ_CP030042_3	3.4\|1046673\|30\|NZ_CP030042\|CRISPRCasFinder	1046673-1046702	30	AP013520	Uncultured Mediterranean phage uvMED DNA, complete genome, group G21, isolate: uvMED-CGR-U-MedDCM-OCT-S39-C26	12136-12165	7	0.767
NZ_CP030042_3	3.1\|1046475\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046475-1046504	30	MT758689	Lactobacillus phage Lbab1, complete genome	20150-20179	8	0.733
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	NZ_CP042415	Leuconostoc citreum strain CBA3624 plasmid unnamed2, complete sequence	13830-13859	8	0.733
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	KM058087	Cronobacter phage vB_CsaP_Ss1, complete genome	35100-35129	8	0.733
NZ_CP030042_3	3.3\|1046607\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046607-1046636	30	NC_009795	Campylobacter concisus 13826 plasmid pCCON31, complete sequence	17771-17800	8	0.733
NZ_CP030042_3	3.1\|1046475\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046475-1046504	30	MG592671	Vibrio phage 2.275.O._10N.286.54.E11, partial genome	28459-28488	9	0.7
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	NZ_AP014867	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK3, complete sequence	115149-115178	10	0.667
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	AP022645	Bacillus wiedmannii PL1 plasmid pBwiPL1-2 DNA, complete sequence	51488-51517	10	0.667
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	CP013001	Bacillus thuringiensis strain XL6 plasmid, complete sequence	382934-382963	10	0.667
NZ_CP030042_3	3.2\|1046541\|30\|NZ_CP030042\|PILER-CR,CRISPRCasFinder,CRT	1046541-1046570	30	CP016196	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence	135779-135808	10	0.667

1. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 0, identity: 1.0

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
gaaaaaatcaaagaaaaagcggcagaagtt	Protospacer
******************************

2. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022485 (Enterococcus faecalis ARO1/DG plasmid pARO1.2, complete sequence) position: , mismatch: 0, identity: 1.0

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagaatatagagctactaaaaacaa	Protospacer
******************************

3. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018540 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-2, complete sequence) position: , mismatch: 0, identity: 1.0

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagaatatagagctactaaaaacaa	Protospacer
******************************

4. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030044 (Enterococcus faecalis strain C25 plasmid pC25-2, complete sequence) position: , mismatch: 0, identity: 1.0

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagaatatagagctactaaaaacaa	Protospacer
******************************

5. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NC_004670 (Enterococcus faecalis V583 plasmid pTEF3, complete sequence) position: , mismatch: 1, identity: 0.967

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagaatatagagctactaaaaataa	Protospacer
***************************.**

6. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.967

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagaatatagagctactaaaaataa	Protospacer
***************************.**

7. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 2, identity: 0.933

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
tctagaagattataaagctactaaaaacaa	Protospacer
********* ****.***************

8. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053900 (Proteus mirabilis strain YPM35 plasmid pJPM35-2, complete sequence) position: , mismatch: 6, identity: 0.8

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
accagaagaatataaagctactaataaccg	Protospacer
 *.***********.********* *** .

9. spacer 3.4|1046673|30|NZ_CP030042|CRISPRCasFinder matches to NC_011774 (Bacillus cereus G9842 plasmid pG9842_140, complete sequence) position: , mismatch: 6, identity: 0.8

accagaaagagttttacgatactatgatga	CRISPR spacer
tgtagaacgagttttacgttactatgatgg	Protospacer
  .**** ********** **********.

10. spacer 3.1|1046475|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NC_014249 ('Nostoc azollae' 0708 plasmid pAzo01, complete sequence) position: , mismatch: 7, identity: 0.767

ctgctctatataaaggatattatttggctt	CRISPR spacer
tttccctatttaaaggatattatttgatgt	Protospacer
.* *.**** ****************.. *

11. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NC_014754 (Sulfuricurvum kujiense DSM 16994 plasmid pSULKU01, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
acaaacatcaaagagaaagcggcagaaaca	Protospacer
. *** ********.************..

12. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NC_020522 (Legionella pneumophila subsp. pneumophila LPE509 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
caaataatcaaagaaaacgcggcacatgcg	Protospacer
 *** ************ ****** * *.

13. spacer 3.4|1046673|30|NZ_CP030042|CRISPRCasFinder matches to AP013520 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G21, isolate: uvMED-CGR-U-MedDCM-OCT-S39-C26) position: , mismatch: 7, identity: 0.767

accagaaagagttttacgatactatgatga	CRISPR spacer
aaaagaaaaagttttacgatactattttag	Protospacer
*  *****.****************  *..

14. spacer 3.1|1046475|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to MT758689 (Lactobacillus phage Lbab1, complete genome) position: , mismatch: 8, identity: 0.733

ctgctctatataaaggatattatttggctt	CRISPR spacer
gcaatatatttaaaggatattatttggcgc	Protospacer
 .. * *** ****************** .

15. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042415 (Leuconostoc citreum strain CBA3624 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
agtaaaatcaaagaaaaaactgcagatggc	Protospacer
.. ***************.* ***** * .

16. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to KM058087 (Cronobacter phage vB_CsaP_Ss1, complete genome) position: , mismatch: 8, identity: 0.733

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
ccgtcaatgaaagtaaaagcggcagaagat	Protospacer
  .  *** **** ************** *

17. spacer 3.3|1046607|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NC_009795 (Campylobacter concisus 13826 plasmid pCCON31, complete sequence) position: , mismatch: 8, identity: 0.733

tctagaagaatatagagctactaaaaacaa	CRISPR spacer
atataaaggataaagagctactaaaaacac	Protospacer
 .  .***.*** ****************

18. spacer 3.1|1046475|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to MG592671 (Vibrio phage 2.275.O._10N.286.54.E11, partial genome) position: , mismatch: 9, identity: 0.7

ctgctctatataaaggatattatttggctt	CRISPR spacer
aaatcatataaaaaggatattatatggcta	Protospacer
  ... **** ************ *****

19. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014867 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK3, complete sequence) position: , mismatch: 10, identity: 0.667

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
cctaaaatcaaagaaaaaggggcatctaac	Protospacer
   **************** ****   . .

20. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to AP022645 (Bacillus wiedmannii PL1 plasmid pBwiPL1-2 DNA, complete sequence) position: , mismatch: 10, identity: 0.667

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
cctaaaatcaaagaaaaaggggcatctaac	Protospacer
   **************** ****   . .

21. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to CP013001 (Bacillus thuringiensis strain XL6 plasmid, complete sequence) position: , mismatch: 10, identity: 0.667

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
cctaaaatcaaagaaaaaggggcatctaac	Protospacer
   **************** ****   . .

22. spacer 3.2|1046541|30|NZ_CP030042|PILER-CR,CRISPRCasFinder,CRT matches to CP016196 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence) position: , mismatch: 10, identity: 0.667

gaaaaaatcaaagaaaaagcggcagaagtt	CRISPR spacer
cctaaaatcaaagaaaaaggggcatctaac	Protospacer
   **************** ****   . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

509465 : 519205

Streptococcus_phage(57.14%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002397890.1\|509465_510104_+	dTMP kinase	M1PSC7	Streptococcus_phage	4.7e-54	53.8
WP_002356367.1\|510123_510453_+	hypothetical protein	NA	NA	NA	NA
WP_002384059.1\|510454_511405_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356371.1\|511521_512361_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002356372.1\|512353_512701_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_078122373.1\|512812_513685_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.2e-81	57.6
WP_002356375.1\|513699_514362_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002356377.1\|514345_515104_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002362328.1\|515229_516348_+	DNA polymerase IV	NA	NA	NA	NA
WP_002397887.1\|516392_516989_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	7.8e-51	56.4
WP_002385686.1\|517021_519205_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	3.1e-286	66.8

DBSCAN-SWA_2

887396 : 958089

Enterococcus_phage(86.79%)

terminase,tRNA,integrase,portal,tail,capsid,head,holin

attL 916689:916715|attR 957584:957610

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002398053.1\|887396_888401_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_002398054.1\|888454_890233_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.5e-52	30.2
WP_002398055.1\|890285_892013_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.6e-35	27.8
WP_002398056.1\|892079_892895_+	MerR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_104846292.1\|893368_897493_+	DUF11 domain-containing protein	NA	NA	NA	NA
WP_002356852.1\|898031_898988_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002359877.1\|898999_899923_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_078122602.1\|899946_901413_+	DUF3502 domain-containing protein	NA	NA	NA	NA
WP_002362905.1\|901483_902119_+	DUF624 domain-containing protein	NA	NA	NA	NA
WP_002398203.1\|902072_903803_+	sensor histidine kinase	NA	NA	NA	NA
WP_002359882.1\|903814_905296_+	response regulator transcription factor	NA	NA	NA	NA
WP_002364393.1\|905336_907478_-	alpha-1,2-mannosidase	NA	NA	NA	NA
WP_002364392.1\|907650_908763_+	FUSC family protein	NA	NA	NA	NA
WP_002356863.1\|908806_909289_-	SRPBCC family protein	NA	NA	NA	NA
WP_002356864.1\|909310_909691_-	VOC family protein	NA	NA	NA	NA
WP_002383776.1\|909902_911369_+	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_002356866.1\|911496_912501_+	nucleoid-associated protein	A0A090D855	Clostridium_phage	8.6e-10	22.3
WP_002398205.1\|912538_912892_-	YxeA family protein	NA	NA	NA	NA
WP_002383773.1\|913090_913795_+	zinc metallopeptidase	NA	NA	NA	NA
WP_002356871.1\|913878_914217_+	hypothetical protein	NA	NA	NA	NA
WP_002372093.1\|914243_915089_-	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_002383772.1\|915145_915997_-	Fis family transcriptional regulator	NA	NA	NA	NA
WP_002362126.1\|916074_916596_+	nucleoside deaminase	NA	NA	NA	NA
916689:916715	attL	NA	NA	NA	NA
WP_002405155.1\|916789_917926_-\|integrase	site-specific integrase	A0A0S2MYI6	Enterococcus_phage	2.9e-211	100.0
WP_010776364.1\|917992_918565_-	hypothetical protein	A0A1B1UZZ9	Enterococcus_phage	9.4e-86	100.0
WP_002389192.1\|918625_918826_-	hypothetical protein	A0A0S2MYA2	Enterococcus_phage	7.4e-30	100.0
WP_002404917.1\|918849_919551_-	DUF5067 domain-containing protein	A0A0S2MYA9	Enterococcus_phage	5.5e-96	100.0
WP_002381617.1\|919639_920113_-	hypothetical protein	A0A0S2MYA6	Enterococcus_phage	5.4e-87	100.0
WP_002404919.1\|920129_920702_-	helix-turn-helix domain-containing protein	C9E2M1	Enterococcus_phage	7.4e-99	98.9
WP_002389146.1\|920860_921094_+	DUF739 family protein	A0A0S2MYC3	Enterococcus_phage	7.8e-39	100.0
WP_002404920.1\|921175_921895_+	oxidoreductase	A0A0S2MYI3	Enterococcus_phage	2.3e-134	100.0
WP_002389279.1\|921910_922159_+	hypothetical protein	A0A0S2MYC6	Enterococcus_phage	2.1e-42	100.0
WP_002389004.1\|922673_922910_+	hypothetical protein	A0A0S2MYD6	Enterococcus_phage	6.2e-36	100.0
WP_002404924.1\|922910_923588_+	ERF family protein	A0A0S2MYH3	Enterococcus_phage	3.3e-122	100.0
WP_002404925.1\|923572_924511_+	DUF1351 domain-containing protein	A0A0S2MYB3	Enterococcus_phage	1.1e-123	99.7
WP_002404926.1\|924507_925188_+	hypothetical protein	A0A0S2MYA3	Enterococcus_phage	4.8e-129	100.0
WP_010776362.1\|925191_926220_+	hypothetical protein	A0A0S2MYA8	Enterococcus_phage	2.9e-162	99.3
WP_002381633.1\|926219_926528_+	hypothetical protein	D2IZR4	Enterococcus_phage	1.6e-44	90.9
WP_010776361.1\|926517_927045_+	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	9.0e-43	58.3
WP_078122599.1\|927056_927386_+	hypothetical protein	NA	NA	NA	NA
WP_025190349.1\|927405_927612_+	hypothetical protein	A0A1B1V001	Enterococcus_phage	5.3e-23	90.3
WP_078122598.1\|927665_928148_+	class I SAM-dependent methyltransferase	D2IYU6	Enterococcus_phage	4.5e-89	96.8
WP_010712230.1\|928341_928521_+	hypothetical protein	D2IZY7	Enterococcus_phage	9.8e-26	96.6
WP_078122622.1\|928620_928905_+	hypothetical protein	S6CQM6	Streptococcus_phage	1.1e-23	77.1
WP_078122597.1\|928904_929129_+	hypothetical protein	NA	NA	NA	NA
WP_078122596.1\|929143_929380_+	hypothetical protein	A0A096XT77	Enterococcus_phage	2.2e-09	43.6
WP_089201922.1\|929385_929709_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_078122594.1\|929705_929957_+	hypothetical protein	A0A0Y0C5A8	Bacillus_phage	7.9e-05	39.0
WP_074653948.1\|929968_930208_+	hypothetical protein	NA	NA	NA	NA
WP_078122593.1\|930210_930702_+	DUF1642 domain-containing protein	D2IZZ0	Enterococcus_phage	9.4e-18	37.5
WP_002357362.1\|931456_931873_+	autolysin	D2IZL7	Enterococcus_phage	1.7e-68	99.3
WP_002404957.1\|933730_934525_+\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	5.6e-121	91.8
WP_138807301.1\|934496_935816_+\|terminase	PBSX family phage terminase large subunit	D2J001	Enterococcus_phage	5.5e-230	91.8
WP_002404959.1\|935833_937372_+\|portal	phage portal protein	A0A1B1V003	Enterococcus_phage	1.9e-287	99.8
WP_002404960.1\|937376_938315_+\|capsid	minor capsid protein	A0A0S2MYG5	Enterococcus_phage	9.7e-173	100.0
WP_002404961.1\|938315_938585_+	hypothetical protein	A0A0S2MYD1	Enterococcus_phage	3.8e-45	100.0
WP_025188184.1\|938679_938943_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	4.1e-44	100.0
WP_002404963.1\|939065_939665_+	DUF4355 domain-containing protein	A0A0S2MYF0	Enterococcus_phage	3.5e-75	100.0
WP_002404964.1\|939677_940610_+\|capsid	phage major capsid protein	A0A1B1V000	Enterococcus_phage	2.3e-174	100.0
WP_002404965.1\|940683_941016_+\|head,tail	phage head-tail connector protein	A0A0S2MYD5	Enterococcus_phage	5.5e-54	100.0
WP_002404966.1\|941012_941348_+	hypothetical protein	A0A0S2MYE1	Enterococcus_phage	1.1e-57	100.0
WP_002402384.1\|941322_941703_+	hypothetical protein	A0A0S2MYE9	Enterococcus_phage	2.1e-65	100.0
WP_002404967.1\|941699_942089_+	hypothetical protein	A0A0S2MYG3	Enterococcus_phage	2.3e-67	100.0
WP_002404968.1\|942104_942635_+\|tail	phage major tail protein, TP901-1 family	A0A0S2MYF4	Enterococcus_phage	1.5e-93	100.0
WP_002404969.1\|942712_943171_+	hypothetical protein	A0A0S2MYH7	Enterococcus_phage	3.7e-77	100.0
WP_002404970.1\|943226_943577_+	hypothetical protein	A0A0S2MYH5	Enterococcus_phage	2.5e-57	100.0
WP_002404971.1\|943669_943927_+	hypothetical protein	A0A0S2MYH1	Enterococcus_phage	1.6e-40	100.0
WP_010776350.1\|943942_947350_+	tape measure protein	A0A0S2MYN1	Enterococcus_phage	0.0e+00	100.0
WP_002373078.1\|947350_948280_+\|tail	tail protein	A0A097BY64	Enterococcus_phage	8.1e-172	99.4
WP_002404973.1\|948296_950315_+	phage minor structural protein, region	A0A0S2MYF5	Enterococcus_phage	1.4e-309	100.0
WP_078122592.1\|950494_952885_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	0.0e+00	99.9
WP_002381665.1\|952976_953204_+	hypothetical protein	A0A0S2MYL7	Enterococcus_phage	1.3e-30	98.6
WP_002369080.1\|953200_953404_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	100.0
WP_002404976.1\|953408_954668_+	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	1.5e-237	97.6
WP_002404977.1\|954769_955366_-	hypothetical protein	NA	NA	NA	NA
WP_002404978.1\|955377_955767_-	hypothetical protein	NA	NA	NA	NA
WP_002404979.1\|956068_957031_+	Abi-like protein	A0A0S2MYH0	Enterococcus_phage	3.1e-182	100.0
WP_002404980.1\|957126_957375_-	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	1.6e-37	100.0
WP_002356881.1\|957708_958089_-	PH domain-containing protein	A6N235	Microbacterium_phage	2.5e-10	33.0
957584:957610	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1038880 : 1117508

Enterococcus_phage(21.43%)

terminase,plate,tRNA,integrase,portal,tail,capsid,head,protease,holin

attL 1068355:1068373|attR 1102087:1102105

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002398071.1\|1038880_1040005_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_002356962.1\|1040184_1041423_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_002425753.1\|1041439_1041955_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_002364252.1\|1042087_1042657_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002356966.1\|1042754_1043120_+	DUF1033 family protein	NA	NA	NA	NA
WP_002362072.1\|1043250_1045332_+	DNA topoisomerase III	NA	NA	NA	NA
WP_002398073.1\|1045416_1046280_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_002356974.1\|1047144_1048563_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_002356976.1\|1048559_1049573_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_002364369.1\|1049577_1051311_+	thiol reductant ABC exporter subunit CydD	A0A2H4UU96	Bodo_saltans_virus	6.5e-13	24.3
WP_002364246.1\|1051307_1053074_+	thiol reductant ABC exporter subunit CydC	W8CYL7	Bacillus_phage	1.6e-22	25.8
WP_002360015.1\|1053153_1054134_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002360016.1\|1054255_1055161_+	prenyltransferase	NA	NA	NA	NA
WP_002360017.1\|1055189_1056401_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002364367.1\|1056714_1059138_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.2e-83	48.0
WP_002356983.1\|1059267_1059969_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002381711.1\|1060086_1060836_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-33	36.5
WP_138807092.1\|1060825_1062655_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_002356987.1\|1062781_1063855_+	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_002360022.1\|1064144_1065473_+	amino acid permease	NA	NA	NA	NA
WP_002398077.1\|1065714_1066683_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_002369171.1\|1066639_1067686_+	secretion system protein F	NA	NA	NA	NA
WP_002356991.1\|1067685_1067961_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_138807094.1\|1067957_1068395_+	hypothetical protein	NA	NA	NA	NA
1068355:1068373	attL	NA	NA	NA	NA
WP_138807096.1\|1068428_1069577_-\|integrase	tyrosine-type recombinase/integrase	A0A1C8E994	Bacillus_phage	1.3e-38	30.7
WP_138807098.1\|1069673_1070402_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	2.4e-22	48.4
WP_002395798.1\|1070435_1070780_-	ImmA/IrrE family metallo-endopeptidase	A0A097QQ08	Enterococcus_phage	5.9e-43	73.7
WP_002395799.1\|1070797_1071184_-	helix-turn-helix transcriptional regulator	A0A097QQ00	Enterococcus_phage	7.8e-60	98.3
WP_002364354.1\|1071431_1071608_+	helix-turn-helix transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
WP_002381719.1\|1071618_1071930_+	hypothetical protein	NA	NA	NA	NA
WP_002395800.1\|1071936_1072116_+	hypothetical protein	A0A0S2MY96	Enterococcus_phage	4.9e-17	78.6
WP_105194762.1\|1072747_1072948_+	hypothetical protein	NA	NA	NA	NA
WP_010826715.1\|1072944_1073238_+	VRR-NUC domain-containing protein	A0A2H4J095	uncultured_Caudovirales_phage	3.6e-09	44.2
WP_016626781.1\|1073227_1074424_+	DEAD/DEAH box helicase	A0A1X9IH01	Staphylococcus_phage	3.8e-20	25.3
WP_010826713.1\|1074425_1074668_+	hypothetical protein	NA	NA	NA	NA
WP_138807100.1\|1074680_1075592_+	endonuclease	A0A2H4JA52	uncultured_Caudovirales_phage	2.9e-12	27.9
WP_002407623.1\|1075593_1075812_+	hypothetical protein	NA	NA	NA	NA
WP_104858190.1\|1075828_1076353_+	hypothetical protein	D7PQ37	Enterococcus_phage	2.8e-20	51.4
WP_128722480.1\|1076330_1077251_+	AAA family ATPase	A0A0A1ENB5	Lactobacillus_phage	4.9e-76	57.3
WP_138807102.1\|1077301_1077814_+	hypothetical protein	A0A0A1ELK1	Lactobacillus_phage	4.5e-23	36.9
WP_105194765.1\|1077836_1079399_+	hypothetical protein	A0A1B1P7M5	Bacillus_phage	4.9e-44	28.8
WP_162301521.1\|1079395_1080148_-	DUF4145 domain-containing protein	M1PSB6	Streptococcus_phage	8.4e-18	37.6
WP_105194767.1\|1080223_1082077_+	DNA primase	H7BVJ4	unidentified_phage	4.6e-41	26.0
WP_033591994.1\|1082456_1082801_+	sigma-70 family RNA polymerase sigma factor	A0A1J0MFD1	Staphylococcus_phage	9.8e-14	36.2
WP_138807104.1\|1082932_1083334_+	hypothetical protein	A0A1B1P7N8	Bacillus_phage	3.3e-13	41.6
WP_002393035.1\|1083333_1083702_+	HNH endonuclease	A0A1B0T6C5	Bacillus_phage	6.3e-43	62.6
WP_105194768.1\|1083814_1084267_+\|terminase	terminase small subunit	A0A2H4JFK0	uncultured_Caudovirales_phage	2.7e-48	69.2
WP_105194769.1\|1084263_1085991_+\|terminase	terminase large subunit	A0A2H4JDG5	uncultured_Caudovirales_phage	8.4e-255	70.7
WP_138807106.1\|1086009_1087221_+\|portal	phage portal protein	A0A2H4J9C7	uncultured_Caudovirales_phage	2.8e-148	67.2
WP_002393031.1\|1087207_1087780_+\|head,protease	HK97 family phage prohead protease	A0A2H4J6Z9	uncultured_Caudovirales_phage	2.7e-61	61.9
WP_105194770.1\|1087791_1089153_+\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	2.7e-123	66.6
WP_002395304.1\|1089155_1089437_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7M9	Bacillus_phage	1.5e-20	58.0
WP_002373974.1\|1089414_1089741_+\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	1.2e-21	54.4
WP_002398474.1\|1089730_1090069_+	hypothetical protein	A0A1B0T6B7	Bacillus_phage	6.4e-26	53.2
WP_105194771.1\|1090058_1090421_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_105194772.1\|1090417_1091065_+\|tail	phage tail protein	A0A2H4JGN2	uncultured_Caudovirales_phage	1.3e-27	34.0
WP_002395308.1\|1091064_1091520_+	hypothetical protein	A0A2H4J956	uncultured_Caudovirales_phage	1.7e-13	35.1
WP_138807108.1\|1091711_1094015_+\|tail	phage tail tape measure protein	V5UPR9	Enterococcus_phage	6.3e-72	51.4
WP_162301522.1\|1094011_1094725_+\|tail	phage tail protein	NA	NA	NA	NA
WP_138807110.1\|1094721_1097517_+	CHAP domain-containing protein	D7RWE0	Brochothrix_phage	7.6e-64	37.5
WP_138807112.1\|1097535_1098417_+\|plate	BppU family phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.1e-11	27.3
WP_138807114.1\|1098409_1099006_+	hypothetical protein	NA	NA	NA	NA
WP_002365086.1\|1099002_1099290_+	hypothetical protein	NA	NA	NA	NA
WP_138807116.1\|1099289_1099799_+	hypothetical protein	NA	NA	NA	NA
WP_002402192.1\|1099815_1100190_+	hypothetical protein	NA	NA	NA	NA
WP_002399193.1\|1100189_1100327_+	XkdX family protein	NA	NA	NA	NA
WP_002383824.1\|1100360_1100594_+\|holin	holin	D2J075	Enterococcus_phage	1.2e-23	69.0
WP_010784051.1\|1100596_1100803_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	1.3e-29	97.0
WP_138807118.1\|1100805_1101906_+	N-acetylmuramoyl-L-alanine amidase	V5URN7	Enterococcus_phage	1.2e-84	46.4
WP_002425755.1\|1102101_1102428_+	type II secretion system protein	NA	NA	NA	NA
1102087:1102105	attR	NA	NA	NA	NA
WP_002398461.1\|1102417_1102852_+	ComGF family competence protein	NA	NA	NA	NA
WP_002360027.1\|1102851_1103205_+	hypothetical protein	NA	NA	NA	NA
WP_138807122.1\|1103333_1104341_+	N-6 DNA methylase	NA	NA	NA	NA
WP_002398460.1\|1104365_1105553_+	acetate kinase	NA	NA	NA	NA
WP_002383133.1\|1105664_1106171_-	universal stress protein	NA	NA	NA	NA
WP_002357068.1\|1106315_1106648_-	hypothetical protein	NA	NA	NA	NA
WP_002360030.1\|1106921_1108199_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-105	49.9
WP_010717036.1\|1108327_1109005_+	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_002398458.1\|1108952_1109447_+	DUF3013 family protein	NA	NA	NA	NA
WP_002357075.1\|1109462_1110410_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_002357078.1\|1110411_1111164_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_002357079.1\|1111378_1113592_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.3e-10	38.0
WP_002357080.1\|1113615_1114062_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002383130.1\|1114201_1114423_+	hypothetical protein	NA	NA	NA	NA
WP_002362049.1\|1114419_1115721_+\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	8.8e-23	26.8
WP_002360034.1\|1115738_1117508_+\|tRNA	aspartate--tRNA ligase	A0A2K9L424	Tupanvirus	3.0e-13	30.3

DBSCAN-SWA_4

1267425 : 1276069

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357268.1\|1267425_1267914_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	7.6e-20	42.7
WP_002371924.1\|1267906_1269031_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002398358.1\|1269182_1269896_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	9.7e-48	42.5
WP_002357271.1\|1269909_1270161_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002374675.1\|1270161_1270836_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_127341785.1\|1270832_1273052_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.7e-147	39.9
WP_127341784.1\|1273027_1274467_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.1e-49	32.1
WP_002398355.1\|1274468_1275500_+	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	1.1e-55	45.2
WP_002374681.1\|1275496_1276069_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.4e-25	35.1

DBSCAN-SWA_5

1398543 : 1435539

Streptococcus_phage(64.71%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010710319.1\|1398543_1398858_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	6.6e-25	52.4
WP_010710320.1\|1398870_1399245_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	5.4e-34	60.9
WP_033591428.1\|1399254_1399590_+	damage-inducible protein J	NA	NA	NA	NA
WP_138807178.1\|1399658_1401026_+	DUF87 domain-containing protein	A0A1S5SFB5	Streptococcus_phage	5.1e-162	65.1
WP_138807180.1\|1401070_1402213_+	DNA (cytosine-5-)-methyltransferase	A0A1S5SEK0	Streptococcus_phage	1.0e-123	65.4
WP_010818847.1\|1402202_1402493_+	hypothetical protein	NA	NA	NA	NA
WP_138807182.1\|1402748_1403933_+	helix-turn-helix domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.0e-143	62.1
WP_002335932.1\|1403947_1404067_+	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_002298822.1\|1404071_1404293_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
WP_138807184.1\|1404868_1405258_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	2.5e-42	65.9
WP_138807187.1\|1406689_1408813_+	FUSC family protein	A0A1S5SF30	Streptococcus_phage	7.1e-179	59.0
WP_073357662.1\|1408809_1409814_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	4.0e-116	62.6
WP_010710331.1\|1409832_1410738_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	4.6e-63	43.6
WP_138807189.1\|1412116_1413286_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_138807191.1\|1413394_1414585_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_010710335.1\|1414761_1415541_+	hypothetical protein	NA	NA	NA	NA
WP_010818839.1\|1415586_1416531_+	LytR family transcriptional regulator	NA	NA	NA	NA
WP_010710337.1\|1416546_1417326_+	LPS biosynthesis protein	NA	NA	NA	NA
WP_010710338.1\|1417337_1418036_+	CpsD/CapB family tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	1.6e-26	37.6
WP_138807193.1\|1418063_1418828_+	tyrosine protein phosphatase	NA	NA	NA	NA
WP_138807195.1\|1418840_1420658_+	polysaccharide biosynthesis protein	A0A2P1ELS8	Moumouvirus	1.7e-27	31.8
WP_138807197.1\|1420641_1421283_+	sugar transferase	NA	NA	NA	NA
WP_138807200.1\|1421279_1422128_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_138807202.1\|1422124_1423276_+	glycosyltransferase	NA	NA	NA	NA
WP_138807204.1\|1423437_1424520_+	EpsG family protein	NA	NA	NA	NA
WP_073506267.1\|1424638_1425454_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.4e-10	40.7
WP_138807208.1\|1425508_1426678_+	nucleotide sugar dehydrogenase	M1HV26	Paramecium_bursaria_Chlorella_virus	1.3e-102	49.6
WP_138807210.1\|1426681_1428094_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_138807212.1\|1428343_1429505_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	3.2e-80	54.2
WP_138807214.1\|1429753_1429954_+	hypothetical protein	NA	NA	NA	NA
WP_010710357.1\|1429943_1430300_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_010710358.1\|1430405_1431950_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_138807216.1\|1431991_1433188_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	2.1e-103	52.6
WP_010710361.1\|1434024_1435539_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.2e-50	39.4

DBSCAN-SWA_6

1754843 : 1769470

Enterococcus_phage(50.0%)

tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002398986.1\|1754843_1755968_-	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	6.6e-75	43.8
WP_002357842.1\|1756086_1756482_-\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_002365555.1\|1756505_1758275_-	hypothetical protein	A0A097BYA8	Enterococcus_phage	8.0e-144	64.3
WP_002365554.1\|1758307_1759765_-	phage minor structural protein	C9E2K6	Enterococcus_phage	6.6e-176	48.0
WP_002365553.1\|1759777_1760704_-\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
WP_138807241.1\|1760705_1763639_-	hypothetical protein	A0A1U9WR55	Streptococcus_virus	1.9e-09	25.0
WP_002382238.1\|1763628_1763922_-	hypothetical protein	NA	NA	NA	NA
WP_002357848.1\|1764014_1764374_-	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002365550.1\|1764406_1764919_-\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002398212.1\|1764931_1765348_-	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|1765568_1765976_-	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_002363798.1\|1765995_1766388_-	hypothetical protein	NA	NA	NA	NA
WP_002365547.1\|1766454_1767297_-	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.3e-30	30.7
WP_002393201.1\|1767315_1768071_-	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_002360496.1\|1768467_1768950_+	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	2.6e-20	47.7
WP_002382232.1\|1768984_1769470_+	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5

DBSCAN-SWA_7

2129549 : 2137463

uncultured_Caudovirales_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_138807273.1\|2129549_2130725_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	5.6e-85	47.7
WP_002361365.1\|2130740_2131256_-	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	7.7e-39	48.8
WP_162301534.1\|2131273_2131768_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002370721.1\|2131835_2132195_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002397944.1\|2132262_2132643_+	hypothetical protein	NA	NA	NA	NA
WP_002355799.1\|2132688_2133048_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_002355798.1\|2133108_2133309_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355797.1\|2133422_2133944_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355796.1\|2134343_2135414_-	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
WP_002361357.1\|2135454_2136411_-	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	4.2e-06	23.9
WP_002364714.1\|2136410_2137463_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP030043

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP030043_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030043_1

750-881

Orphan

Consensus_repeat	Method
TTTCGAAAGTGGGAAAAACCAAC	CRISPRCasFinder
TTCGTTCGAAAGTGGGAAAAACCAACC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP030043_1

>merge|NZ_CP030043|1|750-881|CRISPRCasFinder,PILER-CR
TCCCGAAAGTGGGAAAAACCAACCTTCGGATAAACATGATAAAATCGGCGTTTCTTTCGAAAGTGGGAAAAACCAACGTCCAGAAGAATCCAATAATACCAGTACTTTGTTCGAAAGTGGGAAAAACCAACC

>NZ_CP030043|1|1|750-880|CRISPRCasFinder
TCCCGAAAGTGGGAAAAACCAAC	CTTCGGATAAACATGATAAAATCGGCGTTTC
TTTCGAAAGTGGGAAAAACCAAC	GTCCAGAAGAATCCAATAATACCAGTACTTT
GTTCGAAAGTGGGAAAAACCAAC

>NZ_CP030043|1|1|753-881|PILER-CR
CGAAAGTGGGAAAAACCAACCTTCGGA	TAAACATGATAAAATCGGCGTTTCTTT
CGAAAGTGGGAAAAACCAACGTCCAGA	AGAATCCAATAATACCAGTACTTTGTT
CGAAAGTGGGAAAAACCAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030043.1\|WP_000395511.1\|2971_3586_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP030043.1\|WP_001808810.1\|2454_2619_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP030043.1\|WP_000191454.1\|1735_2416_-\|IS6-like-element-ISEnfa1-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP030043.1\|WP_000384569.1\|2784_2982_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP030043.1\|WP_104765562.1\|3768_4686_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213235
NZ_CP030043.1\|WP_000084745.1\|7592_7985_+\|NimC/NimA-family-protein	unknown	unknown	gnl\|CDD\|227348
NZ_CP030043.1\|WP_013646119.1\|8172_8853_+\|IS6-like-element-IS1216-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP030043.1\|WP_128713131.1\|5427_6258_+\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
NZ_CP030043.1\|WP_000933358.1\|4678_5428_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|378937
NZ_CP030043.1\|WP_161978276.1\|6454_7135_-\|IS6-like-element-ISEnfa1-family-transposase	unknown	unknown	gnl\|CDD\|225853

Protein	Function_ID	Function_description	E-value
NZ_CP030043.1\|WP_000395511.1\|2971_3586_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.09499e-14
NZ_CP030043.1\|WP_001808810.1\|2454_2619_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.46895e-05
NZ_CP030043.1\|WP_000191454.1\|1735_2416_-\|IS6-like-element-ISEnfa1-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.02708e-90
NZ_CP030043.1\|WP_000384569.1\|2784_2982_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.000516033
NZ_CP030043.1\|WP_104765562.1\|3768_4686_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	8.22568e-92
NZ_CP030043.1\|WP_000084745.1\|7592_7985_+\|NimC/NimA-family-protein	gnl\|CDD\|227348	COG5015, COG5015, Uncharacterized conserved protein [Function unknown].	1.3551e-35
NZ_CP030043.1\|WP_013646119.1\|8172_8853_+\|IS6-like-element-IS1216-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.50055e-92
NZ_CP030043.1\|WP_128713131.1\|5427_6258_+\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	5.16829e-101
NZ_CP030043.1\|WP_000933358.1\|4678_5428_+\|ABC-transporter-permease-subunit	gnl\|CDD\|378937	pfam12730, ABC2_membrane_4, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	7.12632e-22
NZ_CP030043.1\|WP_161978276.1\|6454_7135_-\|IS6-like-element-ISEnfa1-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.40725e-89

>NZ_CP030043.1|WP_000191454.1|1735_2416_-|IS6-like-element-ISEnfa1-family-transposase
MTQFKGKQFQKDVIIVAVGYYLRYNLSYREVQEILYDRGIHVCHTTIYRWVQEYGKILYQIWKKKNKQSFYSWKMDETYIKIKGKWHYLYRAIDVDGLTLDIWLRKKRDTQAAYAFLKRLKNQFGEPKVLVTDKAPSIKSAFRKLQKNGLYITTEHRTIKYLNNLIEQDHRPIKRRNKFYQSLRTASTTIKGMEAIRGIYKKSRKEGSLFGFSVCTEIKGLLGIPA
>NZ_CP030043.1|WP_001808810.1|2454_2619_-|helix-turn-helix-transcriptional-regulator
MYQDERKLDFKPLGIAIKKAREAKGWTQEYLAQLVDLTPRSIMGSVAKFPISSF
>NZ_CP030043.1|WP_000384569.1|2784_2982_+|helix-turn-helix-domain-containing-protein
MDYISVKAASEKWGISERRIQKLCEENRIDGTEKFGRAWMIPKDAEKPVDGRMKTRNKQEENHGI
>NZ_CP030043.1|WP_000395511.1|2971_3586_+|helix-turn-helix-transcriptional-regulator
MEFNEKLQQLRTGKNLTQEQLAEQLYVSRTAISKWESGKGYPNIESLKCISKFFSVTIDELLSGEELITLAETENRSNLKKIYNYIYGILDMMAVAFIFLPLYGNSVGGYVYAVNLLSFTATTPFNLAVYWSAFAALIVIGIAKIILTHLDKETWGGIATKCSLGLTALAICFLAAAREPYITALMFLLFVAKIVVWIKQNGTK
>NZ_CP030043.1|WP_104765562.1|3768_4686_+|ATP-binding-cassette-domain-containing-protein
MDYIIETENLTKRYGTATVVDKVNLHVPTGKIYGLLGRNGAGKTTAMKMMLQLAFPTEGTVRLFGTNYKENIHTLYSKVGSIIETPGFYSNLTGYENLQILAKLRGGVSKSGVEKALEVVGLHKEKRKVFSDYSLGMKQRLGIAAAIMHEPELLILDEPINGLDPIGIVEIRSLLSELSHNHGITIFISSHVLSEIEQIADIIGVMHEGHLVEEVNISELHKRNRKYIQFDLSDSEIAGKILESHYHMTDFTVQDGTVRIYDFSQSVGEINREFARNGLLVTRIDDSEENLEDYFSKLIGGGGIA
>NZ_CP030043.1|WP_000933358.1|4678_5428_+|ABC-transporter-permease-subunit
MLNLISCELLKLKRSKMVLISVAGVLSTPLLMLIEALQTHFDKPEIIFTLSDIYSDSVLYIMLLVNIMIYVAIAAYLFSREYTESTLKTILPIPISRTKLLIGKFCTLLLWIVMLTLVTWAGIFIACGLYHAVFTLEGYSLLVAIVWLPKFLFGSILMFLTVSPFVFVAMKTKGFVAPMIGSAVIVMGSAALSNQEWGALYPWTATYFLVQGKLQSTGYPTLLSVSIIILVSAVGFLMTFHHFKKEDLK
>NZ_CP030043.1|WP_128713131.1|5427_6258_+|undecaprenyl-diphosphate-phosphatase
MVLDFIEILKVIFLGIVEGITEWLPISSTGHMILADKFITLNMSEAFKEMFFVVIQLGAILAVVVMFWNKMFPFQLKDKSQPLVKKDTFSLWFKVAVACVPSAIMGILFDDYLDAYLQTPIVISIMLIFYGLLFILIENWNKKRTPTTMALSDISYKTAILIGAFQVLSLIPGTSRSGATIIGALLLGVSRVAAAEFTFFLAVPTMLGASAFKLLKFGFDFTSAELLALVLGMAVAFAVSVLVIKFLMNFIKKHDFKVFGWYRIVLGILVVLTTVM
>NZ_CP030043.1|WP_161978276.1|6454_7135_-|IS6-like-element-ISEnfa1-family-transposase
MTQFKGKQFQKDVIIVAVGYYLRYNLSYREVQEILYDRGIHVCHTTIYRWVQEYGKILYQIWKKKNKQSFYSWKMDETYIKIKGKWHYLYRAIDVDGLTLDIWLRKKRDTQAAYAFLKRLKNQFGEPKVLVTDKAPSIKSAFRKLQKNGLYITTEHRTIKYLNNLIEQDHRSIKRRNKFYQSLRTASTTIKGMEAIRGIYKKSRKEGSLFGFSVCTEIKGLLGIPA
>NZ_CP030043.1|WP_000084745.1|7592_7985_+|NimC/NimA-family-protein
MSQVVDFLNEAKTFYFATVEGDQPRVRPFNAAMERNGKVYLGTTNQKKVYQQLLANSKVEVSGMAKGKWIRLTGEAVIDDTVEAREAMLEANPPLRDWYSADDGKFTVFYLKNMQAVLYSFTGDPEILDN
>NZ_CP030043.1|WP_013646119.1|8172_8853_+|IS6-like-element-IS1216-family-transposase
MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	548-578	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	461-491	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33655-33685	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	449-479	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5472-5502	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43942-43972	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83451-83481	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4997-5027	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	773-803	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7642-7672	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66170-66200	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12175-12205	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60905-60935	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92753-92783	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43888-43918	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4943-4973	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5073-5103	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	602-632	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	515-545	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33709-33739	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	503-533	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	503-533	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5526-5556	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83505-83535	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9536-9566	0	1.0
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	827-857	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43945-43971	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	5000-5026	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	549-575	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	462-488	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33656-33682	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	450-476	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5473-5499	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83452-83478	0	1.0
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	774-800	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7645-7671	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66173-66199	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12178-12204	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60908-60934	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92756-92782	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43891-43917	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4946-4972	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5074-5100	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	603-629	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	516-542	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33710-33736	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	504-530	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	504-530	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5527-5553	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83506-83532	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9537-9563	0	1.0
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	828-854	0	1.0
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7696-7726	1	0.968
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12229-12259	1	0.968
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60959-60989	1	0.968
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92807-92837	1	0.968
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	748-778	1	0.968
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7699-7725	1	0.963
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66227-66253	1	0.963
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12232-12258	1	0.963
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60962-60988	1	0.963
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92810-92836	1	0.963
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	450-476	1	0.963
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	749-775	1	0.963
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66224-66254	2	0.935
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	449-479	2	0.935
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5019-5049	2	0.935
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	694-724	2	0.935
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9482-9512	2	0.935
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5020-5046	2	0.926
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	695-721	2	0.926
NZ_CP030043_1	1.3\|780\|27\|NZ_CP030043\|PILER-CR	780-806	27	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9483-9509	2	0.926
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	MT711976	Streptomyces phage Coruscant, complete genome	87403-87429	5	0.815
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31964-31990	5	0.815
NZ_CP030043_1	1.4\|834\|27\|NZ_CP030043\|PILER-CR	834-860	27	JQ660954	Clostridium phage PhiS63, complete genome	22891-22917	6	0.778
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31963-31993	7	0.774
NZ_CP030043_1	1.1\|773\|31\|NZ_CP030043\|CRISPRCasFinder	773-803	31	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	586541-586571	8	0.742
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	MT711976	Streptomyces phage Coruscant, complete genome	87400-87430	8	0.742
NZ_CP030043_1	1.2\|827\|31\|NZ_CP030043\|CRISPRCasFinder	827-857	31	JQ660954	Clostridium phage PhiS63, complete genome	22890-22920	10	0.677

1. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

2. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

3. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

4. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

5. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

6. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

7. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

8. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

9. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

10. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

11. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

12. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

13. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

14. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

15. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

16. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

17. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

18. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

19. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

20. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

21. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

22. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

23. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

24. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

25. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

26. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

27. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

28. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

29. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

30. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

31. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

32. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

33. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

34. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

35. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

36. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

37. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

38. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

39. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

40. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

41. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

42. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

43. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

44. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

45. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

46. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

47. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

48. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

49. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

50. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

51. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

52. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

53. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

54. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

55. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

56. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

57. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.968

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccaggacttt	Protospacer
************************* *****

58. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

59. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcagcgt	Protospacer
**********************.****

60. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

61. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

62. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

63. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcagcgt	Protospacer
**********************.****

64. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.963

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccaggac	Protospacer
************************ **

65. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcagcgttta	Protospacer
***********************.******

66. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcagcgttta	Protospacer
***********************.******

67. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

68. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

69. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

70. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

71. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

72. spacer 1.3|780|27|NZ_CP030043|PILER-CR matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

73. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 5, identity: 0.815

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaagccaataaaaccactct	Protospacer
********** ******* **** * .

74. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 5, identity: 0.815

tccagaagaatccaataataccagtac	CRISPR spacer
ttttgaagaatcctttaataccagtac	Protospacer
*.. *********  ************

75. spacer 1.4|834|27|NZ_CP030043|PILER-CR matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 6, identity: 0.778

tccagaagaatccaataataccagtac	CRISPR spacer
aaacgaagaaaccaataatatcagtac	Protospacer
    ****** *********.******

76. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 7, identity: 0.774

gtccagaagaatccaataataccagtacttt	CRISPR spacer
attttgaagaatcctttaataccagtactta	Protospacer
.*.. *********  **************

77. spacer 1.1|773|31|NZ_CP030043|CRISPRCasFinder matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 8, identity: 0.742

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
ccaccattaaaaatgataaaaacggcgtttt	Protospacer
*. * . **** ********* ********.

78. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 8, identity: 0.742

gtccagaagaatccaataataccagtacttt	CRISPR spacer
atccagaagaagccaataaaaccactctgtg	Protospacer
.********** ******* **** * . *

79. spacer 1.2|827|31|NZ_CP030043|CRISPRCasFinder matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 10, identity: 0.677

gtccagaagaatccaataataccagtacttt	CRISPR spacer
aaaacgaagaaaccaataatatcagtacaag	Protospacer
.    ****** *********.******

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP030044

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP030042

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP030043

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP030044

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection