CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP034412	Glutamicibacter creatinolyticus strain LGCM 259 chromosome, complete genome	3 crisprs	WYL,csa3,cas3,DinG,DEDDh	1	5	1	0

1. NZ_CP034412

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP034412_1

• CRISPR_ID: NZ_CP034412_1
• CRISPR_location: 166107-166328
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP034412_1

Consensus_repeat	Method
CGCCTTCGGCTTGATGGTTTCCTTGGGCTTCTCCGTAGCCTTCGGCTTTT	PILER-CR

spacers of NZ_CP034412_1

>1.1|166157|66|NZ_CP034412|PILER-CR
CACTTGCGGCTTAGGCTGCGGCTTGGGAGTAGGCTTCGGAGTGGTCTGCGGCTGCGGCTGCGGCTG
>1.2|166273|34|NZ_CP034412|PILER-CR
CCGTCTTTGGCTTCGTTGATTCCTTGGGCTTATC

CRISPR arrays and Neighbor proteins around NZ_CP034412_1

CRISPR arrays

The CRISPR arrays of NZ_CP034412_1

>merge|NZ_CP034412|1|166107-166328|PILER-CR
TGATGGTTTCCTTGGGCTTCTCCGTCACTTGCGGCTTAGGCTGCGGCTTGGGAGTAGGCTTCGGAGTGGTCTGCGGCTGCGGCTGCGGCTGCGGCTTGGGCTTGGCGGTTTCCTTCGGCTTCTCAGCCTTGGGCTTTTCCGTCTTTGGCTTCGTTGATTCCTTGGGCTTATCCGCCTTCGGCTTGCTGGTTTCCTCGGGCTTCTCGGTGGCCTTCGGCTTTT

>NZ_CP034412|1|1|166107-166328|PILER-CR
TGATGGTTTCCTTGGGCTTCTCCGTCACTTGCGGCTTAGGCTGCGGCTTG	GGAGTAGGCTTCGGAGTGGTCTGCGGCTGCGGCTGCGGCTGCGGCTTGGGCTTGGCGGTTTCCTTC
GGCTTCTCAGCCTTGGGCTTTTCCGTCTTTGGCTTCGTTGATTCCTTGGG	CTTATCCGCCTTCGGCTTGCTGGTTTCCTCGGGC
TTCTCGGTGGCCTTCGGCTTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP034412.1|WP_054821224.1|159875_160190_+|thiamine-binding-protein	unknown	unknown	gnl|CDD|376658
NZ_CP034412.1|WP_138925461.1|170850_171900_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|379770
NZ_CP034412.1|WP_138925465.1|175298_175598_+|ArsR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|316153
NZ_CP034412.1|WP_138925455.1|159473_159791_+|AzlD-domain-containing-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138925456.1|160865_161381_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NZ_CP034412.1|WP_054821227.1|162882_164340_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP034412.1|WP_138174615.1|167969_168341_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP034412.1|WP_138925462.1|171907_172804_+|3-hydroxyisobutyrate-dehydrogenase	unknown	unknown	gnl|CDD|130753
NZ_CP034412.1|WP_138925460.1|169037_169892_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138925453.1|158081_158762_+|hypothetical-protein	unknown	unknown	gnl|CDD|178546
NZ_CP034412.1|WP_054821225.1|160294_160666_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138927127.1|161397_162201_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|223498
NZ_CP034412.1|WP_138925464.1|174583_174868_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138174598.1|174864_175302_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138174611.1|169891_170692_-|exodeoxyribonuclease-III	unknown	unknown	gnl|CDD|197320
NZ_CP034412.1|WP_054821581.1|172816_173320_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP034412.1|WP_138925458.1|164509_165472_+|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_CP034412.1|WP_138925454.1|158754_159477_+|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|224215
NZ_CP034412.1|WP_138925463.1|173392_174535_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173840
NZ_CP034412.1|WP_138925457.1|162207_162837_-|DUF2087-domain-containing-protein	unknown	unknown	gnl|CDD|378279

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP034412.1|WP_054821224.1|159875_160190_+|thiamine-binding-protein	gnl|CDD|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	7.08831e-33
NZ_CP034412.1|WP_138925461.1|170850_171900_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|379770	pfam16113, ECH_2, Enoyl-CoA hydratase/isomerase. This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.	1.43048e-136
NZ_CP034412.1|WP_138925456.1|160865_161381_+|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.75626e-08
NZ_CP034412.1|WP_054821227.1|162882_164340_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.96679e-105
NZ_CP034412.1|WP_138174615.1|167969_168341_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	1.57216e-40
NZ_CP034412.1|WP_138925462.1|171907_172804_+|3-hydroxyisobutyrate-dehydrogenase	gnl|CDD|130753	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase. 3-hydroxyisobutyrate dehydrogenase is an enzyme that catalyzes the NAD+-dependent oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde of the valine catabolism pathway. In Pseudomonas aeruginosa, 3-hydroxyisobutyrate dehydrogenase (mmsB) is co-induced with methylmalonate-semialdehyde dehydrogenase (mmsA) when grown on medium containing valine as the sole carbon source. The positive transcriptional regulator of this operon (mmsR) is located upstream of these genes and has been identified as a member of the XylS/AraC family of transcriptional regulators. 3-hydroxyisobutyrate dehydrogenase shares high sequence homology to the characterized 3-hydroxyisobutyrate dehydrogenase from rat liver with conservation of proposed NAD+ binding residues at the N-terminus (G-8,10,13,24 and D-31). This enzyme belongs to the 3-hydroxyacid dehydrogenase family, sharing a common evolutionary origin and enzymatic mechanism with 6-phosphogluconate. HIBADH exhibits sequence similarity to the NAD binding domain of 6-phosphogluconate dehydrogenase above trusted (pfam03446). [Energy metabolism, Amino acids and amines].	8.29448e-113
NZ_CP034412.1|WP_138925453.1|158081_158762_+|hypothetical-protein	gnl|CDD|178546	PLN02961, PLN02961, alanine-tRNA ligase.	9.17587e-30
NZ_CP034412.1|WP_138925458.1|164509_165472_+|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	3.98565e-24
NZ_CP034412.1|WP_138927127.1|161397_162201_+|methyltransferase-domain-containing-protein	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	7.61078e-19
NZ_CP034412.1|WP_138174611.1|169891_170692_-|exodeoxyribonuclease-III	gnl|CDD|197320	cd09086, ExoIII-like_AP-endo, Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases. This subfamily includes Escherichia coli ExoIII, Neisseria meningitides NExo,and related proteins. These are ExoIII family AP endonucleases and they belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER, the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiencies. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity. For example, Neisseria meningitides Nape and NExo, and exonuclease III (ExoIII) and endonuclease IV (EndoIV) in Escherichia coli. NExo and ExoIII are found in this subfamily. NExo is the non-dominant AP endonuclease. It exhibits strong 3'-5' exonuclease and 3'-deoxyribose phosphodiesterase activities. Escherichia coli ExoIII is an active AP endonuclease, and in addition, it exhibits double strand (ds)-specific 3'-5' exonuclease, exonucleolytic RNase H, 3'-phosphomonoesterase and 3'-phosphodiesterase activities, all catalyzed by a single active site. Class II AP endonucleases have been classified into two families, designated ExoIII and EndoIV, based on their homology to the Escherichia coli enzymes ExoIII and endonuclease IV (EndoIV). This subfamily belongs to the ExoIII family; the EndoIV family belongs to a different superfamily.	2.83271e-106
NZ_CP034412.1|WP_054821581.1|172816_173320_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.45713e-20
NZ_CP034412.1|WP_138925465.1|175298_175598_+|ArsR-family-transcriptional-regulator	gnl|CDD|316153	pfam13601, HTH_34, Winged helix DNA-binding domain.	2.91846e-26
NZ_CP034412.1|WP_138925454.1|158754_159477_+|branched-chain-amino-acid-ABC-transporter-permease	gnl|CDD|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	2.23951e-27
NZ_CP034412.1|WP_138925463.1|173392_174535_+|acyl-CoA-dehydrogenase	gnl|CDD|173840	cd01151, GCD, Glutaryl-CoA dehydrogenase. Glutaryl-CoA dehydrogenase (GCD). GCD is an acyl-CoA dehydrogenase, which catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and carbon dioxide in the catabolism of lysine, hydroxylysine, and tryptophan. It uses electron transfer flavoprotein (ETF) as an electron acceptor. GCD is a homotetramer. GCD deficiency leads to a severe neurological disorder in humans.	1.2719e-115
NZ_CP034412.1|WP_138925457.1|162207_162837_-|DUF2087-domain-containing-protein	gnl|CDD|378279	pfam09860, DUF2087, Uncharacterized protein conserved in bacteria (DUF2087). This domain, found in various hypothetical prokaryotic proteins and transcriptional activators, has no known function. Structural modelling suggests this domain may bind nucleic acids.	1.64644e-15

Protein sequences

>NZ_CP034412.1|WP_138925458.1|164509_165472_+|universal-stress-protein
MSDQTPAATEKIEGIVVGVDGSQQSRCALKWAVREASRRGTVLNVVSAYTIPVFAASSMDAGYSTLDDDLIRGGAEDIVRQAREEIGDTDVQVRTYIESGDPAGVLLDLSNDADLVVVGTRGRGGFVGRLLGSVSSALPAHSKCPTVVVPLSMAREQESQEIESREAIVVGVDGSDRARAAVLAAAEAALARDITLRVVCAVAPVSAALAWMPATVDQEAVLEDVRYQMEVGARWLKSHFPDLKLETDVIPGPPVEVLIRESEHAVLTVTGSRGRGGFAGMLLGSTSQGVLHHSKGPVMVVPDSEDPRLADRKDFEEEEQ
>NZ_CP034412.1|WP_054821227.1|162882_164340_-|NCS2-family-permease
MSSSTQTPATLTFAQRVDRYFKISERQSTFSTEIRGGIATFFAMSYIVVLNPLVLSGADASGTELGLQRVAAVTAFVAGILTIIMGVWARHPFAMATGLGVNAFVAITVATNPGLTWQDIMGLVVIAGVVMFVLVLTGFRTAVFNAVPASLKTAIVVGIGMFIALIGLVNSGFVRRIPDAAGTTVPVGLGFDGKLLGWPILVFIVGLLLTMALVVRKVKGAILIGIVAAAVLANILEAMFDIGASSAENPSGWSLVVPSLPSWTLPDLSLIGHVNPIGAFSSLGVTAALLLAFVILLSIFFDAMGTMVGLAAEAGNIDEEGNIPDVEKVLLVDAAGAIVGGGTSSSSSQIFVESGAGIGEGARTGFASVITGLLLLAAMFLTPLIYLVPFEAVAPALVVVGFMMISQVTKIDWNDWGLALPAFLTFTLMPFTYSIANGIGAGFIAFVFIRSAQGRAREVHPLMWVVAAAFVLFFGIGLIEQLTGV
>NZ_CP034412.1|WP_138925457.1|162207_162837_-|DUF2087-domain-containing-protein
MALRIRPVCRTPGHPACATAVMGQCRLTNNGPALRGGRIPLPTCRRLRGMGTQWIEVFAGMKNPGMRHVLGLVLCGQQEQLPEDRTTTKNLERWEKIGLLRQGPGWELNEQLLTSALRARARPKPEGVQRFFNGPRLLTLPARPVERHEVLRQIRDAAIGADEELSEERLNDRLRTIHPDVALLRRYMVDSLLLERSANGSAYRSTGAA
>NZ_CP034412.1|WP_138927127.1|161397_162201_+|methyltransferase-domain-containing-protein
MPGQYPIDTGLAEIEPDPYGAERYILKVNGVPSSHIDLNDPTFLDFEYMRWMQPLFGFGYPAERFDGRQRKLRVLHLGGGGCTMARWVAATYDNARQVVVELDAKLAELVRTQFQVPRAPLVRLRVGDAAQVLPGLSDASRDIIIRDVFAGSTTPVELTTLEYARQVQRVLDVGGTYLANCGDTADLAGARAEAATLSEVFAHVAMVADAPMLKGRRYGNIVFLASDEPLPLDAGFERNLRMAPLPAQVISGAGVRRFIAGASPISG
>NZ_CP034412.1|WP_138925456.1|160865_161381_+|GNAT-family-N-acetyltransferase
MQLRNDYRIRLARTEDIRPALLMKLQAWREAYGHLRPESFFTEQEDQLEAQVQWWERGIEAGAQFYVAELADGTIIGLAGGTPVIDEDKDTGVEIELGMLYVLSPLYGTGVGEHLLETVLCRRDALVWVLEQNARARAFYAKHGFEADGTGEDLAGCWEGLREIRMVRKRG
>NZ_CP034412.1|WP_054821225.1|160294_160666_-|hypothetical-protein
MSNNEKFAWVAAAMVTGFSLVICLAPGLWLAVAGAILLMGCFTVIAQLERGSAQLNRRHWYYLVPLVLAPSICGLLSGPVTFWMGPLIAVVGGVATYYLARSYPVIGEPRPVQEPLVDSEHHV
>NZ_CP034412.1|WP_054821224.1|159875_160190_+|thiamine-binding-protein
MIVAFSVAPSGTGSNPDGSVHDAVAAAVKVVRDSGLPNRTSSMFTELEGSWDEVFDVVKRATEAVAPFGSRISLVIKADIRPGYEGEIHGKLERLESAIEESGQ
>NZ_CP034412.1|WP_138925455.1|159473_159791_+|AzlD-domain-containing-protein
MSELSWWILGACVSAFAIKLCGYFVPRRVLDSPVMSRVAGILTIALLASLVTMNGFTSGQDLVIDARVGALGAAAIALLLRAPFLLVVIAGAGAAILLRATGLAA
>NZ_CP034412.1|WP_138925454.1|158754_159477_+|branched-chain-amino-acid-ABC-transporter-permease
MPRGKLTPATRMGLSIAIATGLYGISFGALAIAAGLNLWQTVALSALMFTGGSQFAFIGVIAGGGTASAAFTAASLLGVRNAVYGMQIKQALRPRAGQVPLMAHVTIDESVATSLAQSSPAEKSRGFWTAGLGVFILWNLFTLAGALLGESLGDPAAWGLDGAAVAAFLGLLWPRLKGAEPILVAIGAALVTALAVPFTAPGLPILIAAAGAVLYALAGSRHAPRATEHGGLREVDGGKP
>NZ_CP034412.1|WP_138925453.1|158081_158762_+|hypothetical-protein
MNTPTSPQEQAYLFDTYLFENEAEVIAAGADDEGQYIALSPNIFHPRGGGQPEDTGTVNGQPVTVSRIESLVVLHGTTGLQVGDRVVATIDAERRKLHAALHTAGHLVGFAGEERGWQHRGHSHFPGQARLDFDPQSLDVPVEQPEQRQAAEAWLQRRVDELLAAGTAVTSTIAADGTRTVSIQGVNSEPCGGTHVQHVSQLRQVQIGQARVKRGVYKVRYDAGHA
>NZ_CP034412.1|WP_138174615.1|167969_168341_-|metallopeptidase-family-protein
MDLQMPDEEFDELVRQAIEAIPASAQRMMDNVAFFIEDEYEPLPGEPENTEILGIYEGIALTERDHDWAAGAMPDRIIIFKNPTLRVCRSPEEVVREVGITVMHELAHHFGIDDARLHELGWG
>NZ_CP034412.1|WP_138925460.1|169037_169892_-|hypothetical-protein
MTPEISGPLQELSAATAHLRVYEPLAAFEDWAQSIILSTPKRDWQQSEEHETRLLWTRTLRRVSDPFPHDEPEFFRAVTIAGYDGTEHTRYCPGQLPARALLAAEQAEEAMRPEVFDLLVPPAAREANAARLDTNRLAEDLTHLNTRTSSWGIPLSWFALFREDDEVRVHQQGDKLRSVRLLTTFSQAVERLSWALNVMVAHAAQAPLFEELGQLGTWLEGFDRESVLELDYGTLAELVWPDDSVNDLHHGLQALEESDATGAAAAYRRLSNRWLGPRHLGRAN
>NZ_CP034412.1|WP_138174611.1|169891_170692_-|exodeoxyribonuclease-III
MKIATWNVNSLRARADRVEDWLRRTDVDVLAIQETKCKDENFPWELFENNDYEVAHFGVNQWNGVAIASRVGLDDVERTFGGQPSFGKGGKDPIQEPRAMAATCNGVRVWSLYVPNGRALDDEHMEYKLQWLDVLKDNAASWLERDPDAQIALAGDWNIAPRDEDVWDIDFFVENRMTHVSEPERAAFRAFETAGFSDPVRPFTEGAFTYWDYTQLRFPRGEGMRIDFALTSPALAARVNNAWIDREERKGKGASDHAPVVVELAG
>NZ_CP034412.1|WP_138925461.1|170850_171900_+|enoyl-CoA-hydratase/isomerase-family-protein
MSDIRIEQRGTLGLITLDRPRALNALTTAMCQQMLDVLLAWRDDPQIHQVAVTGAGERGLCAGGDIVAIYRDINDRDGSTEEFWRIEYQLNALIDEYPKPYIALMDGIVLGGGIGISAHGSHRVVTEASKCGMPEVSIGFFPDVGGTHLLARAPRSAGRYAALTGQSVGAADAIELGLADVHVEQRLLPQLLRELETLSADQVLNQHRSQPAPGILSEPWIRAFEAAEPVDILQQLQRYQDPAAQRAAAALQRACPSSVDLVLALLQEAGSDLREDLRREFRAAVHRLDDPDFGEGIRAQVIDKDRSPQWAARVDGLSAQQRVARHLAPLTGRELDFELIEHGTVSVKE
>NZ_CP034412.1|WP_138925462.1|171907_172804_+|3-hydroxyisobutyrate-dehydrogenase
MDSKPRIGFLGLGHMGLPMVANLHAAGYELKAFDVMPQALQAATGLGITTVQEGAQAAQGVDIVVTMFPTGQHVLDAYRDYLLEAAPPNTLFLECSTIDVAQAREAAELAVAGGHRSADAPVSGGVVGAEAGTLTFMLGAEEADLDQIRPVLEVMGKRVVHCGGHGAGQAAKVCNNMLLGISMIGAAEAFVLGERLGLSHQALFDVISSASGQCWSVTTNCPVPGPVPSSPANRDYAPGFAAALMSKDLGLAASAVQLTDTDAHMGALATQLYKKFSEAGGADNDFSAIITAIREGSL
>NZ_CP034412.1|WP_054821581.1|172816_173320_-|MarR-family-transcriptional-regulator
MTDPLPRDPIAEARSQWVSHGWGQEADAMAAITAVMRTASIFLQRADAILKPHGLTFARFEVLALLGFSSRGSLPMSHASQRLQVHATSLTSSVDRLEAAGLVRRVAHPTDGRTRLLELTGQGRAVLEQARDELNQQLFANSGLQHAEATQLFEILAAFRHRAGDFL
>NZ_CP034412.1|WP_138925463.1|173392_174535_+|acyl-CoA-dehydrogenase
MDLLGIETQLSPAEQARLREVRELVQQQLRTQSVEYWNKEAFPAELVRTLGAAGLGGLQLQSGSQLLRGLIHAEIARADISLSSVVGIHNELIVGMIDSLGSQEQKDTWLPRLSRFEAFGAFALTEPEHGSDVAGGLGTEVVRDGQEYVITGSKRWIGMATLADFALVWARDPESGEVGAYLVESSRPGYRASKIENKIGLRIMQNADIELDQVRIPVANKLPGATSFAAANELLMQSRAWVGWQAVGAMMATLDITRQYSLQREQFGKPIASFQLVQQSLAEIAGHLTVCLSMMRDVALRQEQGELEMVQAALAKSTATRLARESVSQGRALLGGNGVVSDGHMAKVFCDVEILHTYEGTYEINSLIVGRALTGVSAFV
>NZ_CP034412.1|WP_138925464.1|174583_174868_+|hypothetical-protein
MSWWWKPTATAGEHDMGGTGSTIRGTTHRQNTRGRAAMALRITLVLAATVVLGAFIAFALTGAPVYFVAGMSGFAAVGAAASAAHQVTGRKEAA
>NZ_CP034412.1|WP_138174598.1|174864_175302_+|hypothetical-protein
MSFGEREEAARQLAAVQAAQRALASPRRAGARQIGWLSVLLGLLLGALHVLLHFFTPQRSLTSFWVLCAAAAVAITVLALGYRRLHRVLPAGFGRRYLVALAASLVLYAGLLALIMTPMPLAVVLLLGAVVALPLAVAGGWMIRQ
>NZ_CP034412.1|WP_138925465.1|175298_175598_+|ArsR-family-transcriptional-regulator
MTQHPRARMNEDFTNPVRLSLMVALQQVDEVDFRTLRETLGVSDSVLSRHLAALEEKGHLVIRKGFVGKRPRTWAHLSKTGRQSLAEHVQALREITGTL

Crispr_ID: NZ_CP034412_2

• CRISPR_ID: NZ_CP034412_2
• CRISPR_location: 2655313-2655824
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NZ_CP034412_2

Consensus_repeat	Method
GCATCAGCGTTGGCGTCNGC	CRT

spacers of NZ_CP034412_2

>2.1|2655333|22|NZ_CP034412|CRT
ATCCGCCTGGGCGTTGGAAGTT
>2.2|2655375|34|NZ_CP034412|CRT
ACCGGACTCAGCATCAGCGTTGGTGTCAGCCTCA
>2.3|2655429|40|NZ_CP034412|CRT
ATTAGCCTGAGCATCAGCGTTGGCGTCGGCATTAGCCTGA
>2.4|2655489|40|NZ_CP034412|CRT
ATCAGCGTTGGCATCAGCCTGAGCGTCCGCACCGGACTCA
>2.5|2655549|34|NZ_CP034412|CRT
CTGAGCATCCGCACCGGACTCAGTATCAGCGTCG
>2.6|2655603|28|NZ_CP034412|CRT
TTCAGCGTCGGCGTCGGCATTAGCCTGA
>2.7|2655651|40|NZ_CP034412|CRT
ATCAGCGTCGGTGTCGGCATTAGCCTGAGCATCAGCATCC
>2.8|2655711|40|NZ_CP034412|CRT
CTCAGCATCAGCGTTTGCGTCGGCGCTGGCATCAGCCTCA
>2.9|2655771|34|NZ_CP034412|CRT
AGTTGCATCAGCCTGAGCGTCCGCACCGGACTCA

CRISPR arrays and Neighbor proteins around NZ_CP034412_2

CRISPR arrays

The CRISPR arrays of NZ_CP034412_2

>merge|NZ_CP034412|2|2655313-2655824|CRT
GCATTAGCCTCGGCACTCGCATCCGCCTGGGCGTTGGAAGTTGCATCAGCCTGAGCATCCGCACCGGACTCAGCATCAGCGTTGGTGTCAGCCTCAGCATCAGCGTTGGCGTCAGCATTAGCCTGAGCATCAGCGTTGGCGTCGGCATTAGCCTGAGCATCAGCGTTGGCGTCAGCATCAGCGTTGGCATCAGCCTGAGCGTCCGCACCGGACTCAGCATCAGCGTTGGCATCAGCCTGAGCATCCGCACCGGACTCAGTATCAGCGTCGGCATCAGCGTTGGCGTTGGCTTCAGCGTCGGCGTCGGCATTAGCCTGAGCATCAGCGTTGGCGTCAGCATCAGCGTCGGTGTCGGCATTAGCCTGAGCATCAGCATCCGCATCAGCGTTGGTGTCAGCCTCAGCATCAGCGTTTGCGTCGGCGCTGGCATCAGCCTCAGCATCAGCGTTGGCGTCAGCAGTTGCATCAGCCTGAGCGTCCGCACCGGACTCAGCATCAGCGTTGGCGCTGTG

>NZ_CP034412|2|1|2655313-2655824|CRT
GCATTAGCCTCGGCACTCGC	ATCCGCCTGGGCGTTGGAAGTT
GCATCAGCCTGAGCATCCGC	ACCGGACTCAGCATCAGCGTTGGTGTCAGCCTCA
GCATCAGCGTTGGCGTCAGC	ATTAGCCTGAGCATCAGCGTTGGCGTCGGCATTAGCCTGA
GCATCAGCGTTGGCGTCAGC	ATCAGCGTTGGCATCAGCCTGAGCGTCCGCACCGGACTCA
GCATCAGCGTTGGCATCAGC	CTGAGCATCCGCACCGGACTCAGTATCAGCGTCG
GCATCAGCGTTGGCGTTGGC	TTCAGCGTCGGCGTCGGCATTAGCCTGA
GCATCAGCGTTGGCGTCAGC	ATCAGCGTCGGTGTCGGCATTAGCCTGAGCATCAGCATCC
GCATCAGCGTTGGTGTCAGC	CTCAGCATCAGCGTTTGCGTCGGCGCTGGCATCAGCCTCA
GCATCAGCGTTGGCGTCAGC	AGTTGCATCAGCCTGAGCGTCCGCACCGGACTCA
GCATCAGCGTTGGCGCTGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP034412.1|WP_138926758.1|2663733_2665290_+|histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
NZ_CP034412.1|WP_138926754.1|2657710_2658685_+|GHKL-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP034412.1|WP_138926749.1|2651151_2652534_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143418
NZ_CP034412.1|WP_138926753.1|2656299_2656923_+|DUF3060-domain-containing-protein	unknown	unknown	gnl|CDD|371435
NZ_CP034412.1|WP_138926751.1|2653742_2654531_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138926750.1|2652597_2653716_-|HTTM-domain-containing-protein	unknown	unknown	gnl|CDD|214802
NZ_CP034412.1|WP_138176537.1|2642967_2643408_-|DoxX-family-membrane-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138927253.1|2665826_2668382_-|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|223256
NZ_CP034412.1|WP_138926746.1|2644464_2645694_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173840
NZ_CP034412.1|WP_138926755.1|2658681_2659740_-|LD-carboxypeptidase	unknown	unknown	gnl|CDD|132883
NZ_CP034412.1|WP_138926752.1|2654717_2655257_-|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138926756.1|2659812_2662530_-|ornithine-decarboxylase	unknown	unknown	gnl|CDD|224893
NZ_CP034412.1|WP_138926757.1|2662911_2663451_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138926747.1|2645797_2648377_-|ATP-dependent-helicase-HrpB	unknown	unknown	gnl|CDD|224557
NZ_CP034412.1|WP_138176187.1|2649766_2650909_+|L-glyceraldehyde-3-phosphate-reductase	unknown	unknown	gnl|CDD|381376
NZ_CP034412.1|WP_138926759.1|2665394_2665817_+|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|376751
NZ_CP034412.1|WP_138926748.1|2648383_2649166_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|274729
NZ_CP034412.1|WP_138175917.1|2656986_2657718_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP034412.1|WP_138176535.1|2643660_2644350_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_CP034412.1|WP_054822059.1|2668588_2669059_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP034412.1|WP_138926758.1|2663733_2665290_+|histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NZ_CP034412.1|WP_138926749.1|2651151_2652534_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143418	cd07100, ALDH_SSADH1_GabD1, Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like. Succinate-semialdehyde dehydrogenase 1 (SSADH1, GabD1, EC=1.2.1.16) catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde (SSA) to succinate. SSADH activity in Mycobacterium tuberculosis (Mtb) is encoded by both gabD1 (Rv0234c) and gabD2 (Rv1731). The Mtb GabD1 SSADH1 reportedly is an enzyme of the gamma-aminobutyrate shunt, which forms a functional link between two TCA half-cycles by converting alpha-ketoglutarate to succinate.	0
NZ_CP034412.1|WP_138926753.1|2656299_2656923_+|DUF3060-domain-containing-protein	gnl|CDD|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	0.00012572
NZ_CP034412.1|WP_138926750.1|2652597_2653716_-|HTTM-domain-containing-protein	gnl|CDD|214802	smart00752, HTTM, Horizontally Transferred TransMembrane Domain. Sequence analysis of vitamin K dependent gamma-carboxylases (VKGC) revealed the presence of a novel domain, HTTM (Horizontally Transferred TransMembrane) in its N-terminus. In contrast to most known domains, HTTM contains four transmembrane regions. Its occurrence in eukaryotes, bacteria and archaea is more likely caused by horizontal gene transfer than by early invention. The conservation of VKGC catalytic sites indicates an enzymatic function also for the other family members.	1.47837e-32
NZ_CP034412.1|WP_138927253.1|2665826_2668382_-|excinuclease-ABC-subunit-UvrA	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP034412.1|WP_138926746.1|2644464_2645694_+|acyl-CoA-dehydrogenase	gnl|CDD|173840	cd01151, GCD, Glutaryl-CoA dehydrogenase. Glutaryl-CoA dehydrogenase (GCD). GCD is an acyl-CoA dehydrogenase, which catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and carbon dioxide in the catabolism of lysine, hydroxylysine, and tryptophan. It uses electron transfer flavoprotein (ETF) as an electron acceptor. GCD is a homotetramer. GCD deficiency leads to a severe neurological disorder in humans.	2.42583e-137
NZ_CP034412.1|WP_138926755.1|2658681_2659740_-|LD-carboxypeptidase	gnl|CDD|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	1.86622e-100
NZ_CP034412.1|WP_138926756.1|2659812_2662530_-|ornithine-decarboxylase	gnl|CDD|224893	COG1982, LdcC, Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism].	8.102e-126
NZ_CP034412.1|WP_138926747.1|2645797_2648377_-|ATP-dependent-helicase-HrpB	gnl|CDD|224557	COG1643, HrpA, HrpA-like helicases [DNA replication, recombination, and repair].	0
NZ_CP034412.1|WP_138176187.1|2649766_2650909_+|L-glyceraldehyde-3-phosphate-reductase	gnl|CDD|381376	cd19150, AKR_AKR14A1, Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ/AKR14A1) and similar proteins. Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ), also called GAP reductase, is a founding member of aldo-keto reductase family 14 member A1 (AKR14A1). It catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). It is also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo.	3.57781e-178
NZ_CP034412.1|WP_138926759.1|2665394_2665817_+|aspartate-1-decarboxylase	gnl|CDD|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	3.87936e-78
NZ_CP034412.1|WP_138926748.1|2648383_2649166_-|alpha/beta-fold-hydrolase	gnl|CDD|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	3.5921e-29
NZ_CP034412.1|WP_138926754.1|2657710_2658685_+|GHKL-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.3652e-38
NZ_CP034412.1|WP_138175917.1|2656986_2657718_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.50017e-71
NZ_CP034412.1|WP_138176535.1|2643660_2644350_+|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.89865e-14

Protein sequences

>NZ_CP034412.1|WP_138926752.1|2654717_2655257_-|LPXTG-cell-wall-anchor-domain-containing-protein
MNITSPKENSEVEGPNITISGVSDPNAKVTVSVSRVPEGAAAKAAVTNPQQETDADDEGNWSVTVAGVESGKYTAHAADGLTEDTTTFFVVDPSVGSDSSATEGGSDSSATEGASDTSSTETDASTGGKDEDSPSKPESGGNKDELADTGANGVLIAAGAALILALAGAGVLFARRKKA
>NZ_CP034412.1|WP_138926751.1|2653742_2654531_-|hypothetical-protein
MTETDSTSKIKKRPLWLRLVAVACIGLTIWHVYATFLWVSPPSELRNAIPGNALRSYIQPMFGQSWSVFAPKPIDGDYSFEVRAMLEDTSGKPSPTQWVDAVNLEMGMIHRNLFPARASLAGNQLASDYRTGWQKLNDRQRDIVKLGYFKGDDWTQRLARELNERAAKTGSSQKNTMSFVESERTASAYATQVAKALWGQEVRSVQFRVGRQGVIPFEQRNKPGAIRPSPAIIESGWRGLTVRDGQNEQNFAEVFNSLEGVK
>NZ_CP034412.1|WP_138926750.1|2652597_2653716_-|HTTM-domain-containing-protein
MKLARIWSAFWKEGPVHLLDASRGVVAIIDDWLFDGKHATYGIAVARMIFAASALGLLMTNFSTRHYTYGSGAAWSGQLEEPNGSFAGNPFFGLFFNIASNDAAVTAYFLMLIVLAAALLVGYRARIVLPVFLALWIGLIETPYFGGDQGDNALRIALFLMLFTDHSAKWSFDERRRERNTNYQGSLLAKMWRGTRFVPENLTNLWHNLALVVLACQVFMIYVSGALFKAGGKPWQNGTAIYGPLHTMRFGPWPELSELVTTFGWVVAVGSIGSVILQVCFPGALLFRWTRIPVLFAMISFHAGIAILMGLPWFSLAMVGIDAIFIRDVTWARLTNWFKRSARETEYVQTASNVEETSPIESHEEYRVTVGA
>NZ_CP034412.1|WP_138926749.1|2651151_2652534_+|aldehyde-dehydrogenase-family-protein
MSAQTYKVLNPATGETVEEFPVATDEQVQETLSAASSAYESWGKTDINERAKIVHRIAELFGERAEELGKIMTTEMGKPLSEAVGEAEFCKDIFEYFATEGPTLAADQEIKSLSGGRAVVQKRPIGPLLGIMPWNFPLYQVARFAAPNLMLGNTIILKHAESCPRSALAIQEIFDEAGVPAGVYNNLFATHDQISTIIEDPRIQGVSLTGSERAGAIIGEQAGRNLKKAVLELGGSDPFVVLDSQNISDIAETAWGFRIDNTGQACNSNKRMIVMEDIYDEFVSELTKRAEGLQPGDPMKEEDGTFAPMSSRKAAEDLHEQVQDAVSKGATLHAGGVLHDGPAAYYSPAVLTGVTKDMRAYYEELFGPVAVVYKVSSDEEALEMANDTVYGLGGSVHSEDRARAEKVAMGLQAGMASVNAASAEGAEMPFGGVKRSGFGRELGPLGMDEFVNKRLYYIGE
>NZ_CP034412.1|WP_138176187.1|2649766_2650909_+|L-glyceraldehyde-3-phosphate-reductase
MNRIRPFSCPSLELVQWHLPPRRERCTVEYERFQPVVDSHRPWVASEDRYEHFGYRRVGASGLLLPPISLGLWWNFGDNRTFDSQREILRHAFDSGINHFDLANNYGPPAGSAEENFGRMLRGDFRPYRDELIISSKAGWDMWQGPFGTFGSRKYLMASADASLERLGVDYVDVFYSHRFDPKTPLEETIGALDTLVRQGKALYVGISSYSAERTAEAAAIAKDLGTPLVIHQPSYNMLNPWVEHGLLQTLEQERMGSIAFTPLAQGLLTNKYLGTTDVERSGGRRSLQDQLTEENLKKIRSLNELAQQRGQSLAQMAIAWLLRDGAATSVLIGASSTQQLDENLAALQNTEFTTQELEQISTITQGDAGIDWWKSSAIG
>NZ_CP034412.1|WP_138926748.1|2648383_2649166_-|alpha/beta-fold-hydrolase
MPSITNPADGTEIFFDDDRAAGEAVVYLHGSALSRSIWRGLGYTKTVGAGRRNIRIDLRGHGKSGKPHRTESYTMELITGDVLAVLDSLGIERAHLLGYSFGSRTALSIALQQPERVLSLSMLGGTYAIESGEIDGLFFEGYLQVLRAGDIEGFVSGQGRLDPATRMAFLANDPLALAAYFEAAETLQRLELEQLRALRVPTLLLAGTRDQPRFEHNKVMARTMPHARLVPLVDRTHGSTLFPIEPGATQIAQFLDRHDR
>NZ_CP034412.1|WP_138926747.1|2645797_2648377_-|ATP-dependent-helicase-HrpB
MMVNRASAPFDLAAIGRGLAFGPAHTQISRRLGDAVDAPLVIQAPPGSGKTTIVPPTVANALAAAGLGGRVIVTQPRRMAARAAARRLAQLDGSELGERIGFSVRGQSLSGPRTRIEFVTAGLLLRRLLADPDLASVGAVIVDEVHERSIETDLVLAMLNQVNQLRDDLALLVMSATLHAEDLAGYLGRGAAAGIISGSGIQHPVAEEFCSYSGTRNAERGLERGYLDHVAATAVEQTARNTAQGPARDTLVFVPGAGEVERVRALAAGDPRFEVLALHGQVEAAAQDAILQDPGPAARPRIIISTPIAESSLTVPRVNLVVDAGYAREPRRDAVRGMSGLVTVVASRASATQRAGRAGRLEPGRVVRTLDQRSFAAAPAFTSPQIATAELTQAALYLAAWGTPRGEGLELWQQPPAAALDDAESVLRSLGAIDETGQLTPAGQRLVQVPADPRLARALLEGARHFGPRAAAEAVAMLSGTERAGGADAGALLRELRRGGHPGHGPWAAETRRFAQLLRRQQAPAEVAPTPGAGAESAALAGVMALAYPQWVGRLVAGDEYLLASGTRASLPRHSPLHGHEFLAIADVARAGAGAVIRSAAGIELELLLELLPQMHRVQTRAEFTAGKVSARQVQLLGAIELSTRPVKPTAEQAGAAVLRALQAEGLGIFGQQPKFQALRARLALAHRELGEPFTAMDEPALLQRADEWLQEGLLQMARGTAAAKVDLAQALRSLIPWQHAHDLDELLPERLQVPSGSRIALQYPEPGTAQGRVVAAVKLQECFGLAQTPRLLHGQVPIQFHLLSPAGRPLAVTDDLRSFWDGPYRQVRAEMRGRYPKHPWPENPWEHVATAKTKNRLR
>NZ_CP034412.1|WP_138926746.1|2644464_2645694_+|acyl-CoA-dehydrogenase
MTQETTYEFPTGVTEPDYELWTTDVEIDPTGVFEDLDPEDRAWWDKARAFTLDEVRPVAHEYWETADYPLHLVKKLGDADLLRDGQTPKGYAPMSAMAAGLVNMELHRGDGSVGTIVGVQAGLALRSILQCGSPEQIEKFGVPMLRGELPGAFALTEPTHGSDSVSLETRATRVEGGYVLNGEKKWIGNGSVGGISVVWARDDEGKVRGLLVDQQSAGYTATTIKNKLSLRAIWQAHIRLENVFVPDEMVLPGANSFKDTAAVLFATRLGVAWAAVGHATACYESAVAYAKQRVQFGRPLAASQVVQERLARMQSELATIQLLAVQSTRREMAGKLTGPAASLAKYTATRTARSIAANARDLLGGNGILTDNRVARHFADMEALHTYEGTETVQALIMGRAITGISAFA
>NZ_CP034412.1|WP_138176535.1|2643660_2644350_+|TetR-family-transcriptional-regulator
MITSSAVPVAALELLIDQGFDATSVDELANAAGMSRSTFFRRFGSKENMVFADQEMIITHLQTVLGTSSAPTMQALTEAVSVVFDQYTANPPAAELRHQLLQEVPALRDRELVSTHRFERAFNDYLRAKGLFAAPGERSLRLGLSAALVSIHNDHLRTWLRDHAATGRDELAADVRRFLSRFADLISPEQAETAPGQRTTVVVSVINPGGDQQAVLDEVAQALKQAGGI
>NZ_CP034412.1|WP_138176537.1|2642967_2643408_-|DoxX-family-membrane-protein
MGISIANAALRLVSGAYILNSGINKLRLDEESAAGLQQMASNGVPQLGNMEPAAFGKAVSATEISLGSALLLPLVPSRLAGLGLAGFSGVMLSMYLRTPGLTESDGIRPTAEGGTLAKDVWLAGIAVALIFGRRSYRQQKKKNNNK
>NZ_CP034412.1|WP_138926753.1|2656299_2656923_+|DUF3060-domain-containing-protein
MEKKTMHSAGLSLAVLLLASAGLSGCVSVQPENGTETSSGPITSPSAPEQDTQSPTAQPSPSSSAPAATSSSPAAKGAQEASFSEIFKSINSNAAKKLECLDEDHGRNDADDLYIKDKNTVISITGDCDDVVISGHNLVIAATEIDDLIVRGNNNVIAVQDLDNVEVSGSGNHVGWDPAYEDDPDVENHGSKNVLRHDAVGSAELDL
>NZ_CP034412.1|WP_138175917.1|2656986_2657718_+|response-regulator-transcription-factor
MTASDGASVLLVDDEQDILATLGGYLRRSGLEVHTAGNGAEALQLLESQPVSVIVSDVMMPYLDGRALLRTLREREDWTPVILLTVVGEADERSAALDEGADDYLNKPFAPQELLSRIRAVLRRLQSATQSLGNAQVLVAEHAGGTLKLDRSARRVWNSGSEVTLTPKALTLLEYLMSRPDEVHSRERLLETLWGFEFAVSTRAVDHRIAEIRRSFGDDAAAPTLIETVPGHGYRLAAQVRRG
>NZ_CP034412.1|WP_138926754.1|2657710_2658685_+|GHKL-domain-containing-protein
MARVRTTTDTGRRAADGAQRALLFALFSIPVLALAAAILLFFLAGGLDLSILMPLWLVPLVLGVAAFTGCALVLRQRRSTERQIQDLRAKITSEGDQARRRLLRRLDHELKNPLTVLQAVISGSEDQLPDAASWGSVATQTRRLSRLVGDLRGLAELEVAQLERVQVDVEQLLRDVLDDTAEGPQGRDAEQRRISLHLPKAPWPLPAIQGDPDLLRLSLHNLLSNAIKYSSAGDSIEITAQELDGSLIIDIADTGRGIPEEEQDLVLEELARASNARDMPGSGIGLALVRVIVARHGGTLILRSRDGHGTSVSMRLPLHPPAAA
>NZ_CP034412.1|WP_138926755.1|2658681_2659740_-|LD-carboxypeptidase
MTWTDKHVTVPARLRPGAQVRVVAPSCSRSYVMEHDNTRWINERFAALGIKLSFGWHVDERDDFDSSSITSRLEDLHAAFADPAVDGIMSVIGGFNANELLPYLDWDLIAANPKVFCGYSDFTVLANAIHARTGMITYVGPHWSMFGMRDHFEPTGQWFTAATSGQAWSIEPATAYTDDLWFMNQDGRQTLPTDGPWVLREGAGTGRVIGGNLCTLNLLQGTGLMPRLEGAMLFLEDDAAGDIHEFARNLAALLQRPDAAGITGLGIGRFQQDSGVTRSMLQQAVDKHPLLDSVPVVANLDFGHTSPMFTLPIGGQARLAATPAQGQPDRVQLRFAHRREQLDQAGGSAENC
>NZ_CP034412.1|WP_138926756.1|2659812_2662530_-|ornithine-decarboxylase
MDTGLAKPAVNATGTPESAWRRRKDAWEHLGYILSELVRVVGNGSGEPETLVQEAGKLIGLIAAIEPYWATPGISYFNEMVAALEADDYDPAMEKVYLVNQTFRSQTQYIEPDTLHAEDEENEPTARFTPVVEVLMVDNGRVEEIEGFKQEMLDQRRSSDEFTYNLVVVPSVEDALVALMINPTIQTCVLTPRFELHTRQKLSTALHGYISAQMDGMFSSGKQVDLLLDLERLVERLRPEVAVYLVAGVALESLARELTGRFRRIFSRNDGMDLHLSIIGEILSRYETPFFNALQRHARRPGGVFHAMPISRAGSVQNSPWARDLVDFYGINLLLAETSATSGGLDSLLDPHGSIRDAHELAARAFGSHRTYFVTNGTSTANKIVHQSILAPGDIVLVDRNCHKSHHYSLVLAGAHVKYLEAYPLQEHAIYGAVPLREIKKALLELRRAGKLHKVKMITLTNCTFDGIIYDPRRVMEECLAIKPDLVFLWDEAWYAFAGFHPIYRKRTAMAAARGLEADLSTAQHRRRYEEQVGQLPEPGTHEDPANDEAWLNARLIPDPQATRLRIYATQSTHKTLTSLRQGSMIHVHDQDFASRNANSFREAYMTHTSTSPNYQILASLDIGRRQVELEGYALVQRQVDLALSISKAIARHDLLRKYFRVLDSSDLIPEQFRTSRNTNPVRDGLAAWDQAWDTDEFVVDPSRLTLDISRTGVDGDTFKHSYLMDGHAIQVNKTSRTSVLLMTNIGTNRSAVAYLIEVLIKIANELERQRRLDGRDAYPAQPTAQPQVPLPDFSHFAPAFDGGAQSGDMRRAYYLTYDDPATTFYHSPAIRERIAAGQEVVSAAFVTPYPPGFPVLVPGQVISLPILDYMDALDTREIHGYHRQYGYQVFTPEALALVEQDKRG
>NZ_CP034412.1|WP_138926757.1|2662911_2663451_-|hypothetical-protein
MSGNLFARSVHDLTAAAWFGGSLMGAVGLNGATSEAKDATERTRLSSLGWKKWAPVQTGAFAAHLASLGPILWENKGRYATQDGVMAWTWIKTGVTLAGAAVTFYAAVLGKKVDQLAEEGAKGATEPRAGSSDELAKAQKQLRQLQWLIPGFAATVIVLGAQHGEMQRPKNVKLGLLKR
>NZ_CP034412.1|WP_138926758.1|2663733_2665290_+|histidine-ammonia-lyase
MEANLKNSAVTLNLGGTTAEDVIAVARQQAPVMIADAVLAELGRVRTHIEQMAASDTPVYGVSTGFGALATRHIPQADRAKLQRSLIRSHAAGMGEPVEREVVRALMFLRAKTLATGRTGVRPVVLQTMVEVLNAGITPVVREFGSLGCSGDLAPLAHCALVLMGEGEAVDRQGVLRPVPQLLAEAGIEPLVLEEKEGLALINGTDGMLGMLLLALADLGELVDIADLSAAMSVEAQLGTDQVFRADLHEPLRPHPGQATSAANMFNALAGSPIVASHREGDGRVQDAYSLRCSPQVTGATRDTMDHAATVARRELAAAIDNPVVLPDGRISSNGNFHGAPVAYVLDFLAIAVADLGSIAERRTDRMLDPARSRDLPAFLADDPGVDSGMMIAQYTQAGLVAENKRLAVPASADSIPSSAMQEDHVSLGWHAARKLRKSVENLRRILSIELVVAGRALDLRRPLQPSPVTGAVLGLLRSKVQGPGPDRFLSADLEAAYQLLADGQVHRVLREALAGGR
>NZ_CP034412.1|WP_138926759.1|2665394_2665817_+|aspartate-1-decarboxylase
MQRTMFKSKIHRATVTQADLHYVGSVTIDQDLLDASDILPGELVSIVDVTNGARLETYTIAGERGSGVVGINGAAAHLVHPGDLVIIISYAQMEDAQARAYAPAVVHVDEHNRMIHLGDDPAVAVADGVQTPPFAQVTGN
>NZ_CP034412.1|WP_138927253.1|2665826_2668382_-|excinuclease-ABC-subunit-UvrA
MHPTPGADPAPALPAPGATAGQDGFLHVRGASENNLQNVEVRIPRDAIVAFTGVSGSGKSSLAFGTIFAEAQRRFLESVAPYARRLISQGHTPKVEYISGLPPAVALQQRRAGSSSRSSVGTLTTLSNSVRMLFSRAGSYPPGAARLDSDAFSPNTAVGACPQCHGLGQAHTVSEELLVPDPSLSIRQGAIAAWPGAWQGKNLRDVASHLGYDVDKPFGQLARKDRDWLLFTDEQPVVEVTPERDRIEKPYKGRFWSAKRYVLHTVAESKSETMRAKALRFLKTGPCPLCGGSGFRQESLAVRFAERTIAEFNAASLTELAELLDTYQPQQQATAAEQQVAQTIGTDLRARIQVLLDLGLGYLSLNRATPTLSPGEMQRLRIATQLRSGLFGVIYVLDEPSAGLHPADAQPLIQVLGSLKEAGNSVFVVEHNMDVVAAADWIVDVGPRAGRNGGQVLYSGPVPGLKEVQSSVTRRFLTPPPAPDHQIRQASGWLELQGVNLHNLMDLQARFPLGVFTAVTGVSGSGKSSLVSHALAQSVQGKLRTAPASPRNAEPSEEVTAQVGRVLGAEALNRCVVMDQKPIGRTPRSNLATYTGLFDAVRKTFADTQLARERGYGAGRFSFNVAGGRCETCQGEGYLEIELLFLPGTYGPCPTCHGARYNPQTLEVTYQPTDGAQPKNIAEVLAMSVDEAAEFLHPIPAAARALATLQEVGLGYLSLGQPATELSGGEAQRIKLATELQRARRGHTLYLLDEPTTGLHPADVQLLVAQLHRLVEQGNTVVVVEHHLDVVAAADWVIDLGPAGGDAGGRIIAAGTPQQVAANPASRTGTYLAARFPDQDRPGTKPQPDAG
>NZ_CP034412.1|WP_054822059.1|2668588_2669059_+|hypothetical-protein
MPDDSPEAPHRQWNELLQEMRVMQTGIQILAAFLVVLPFQSRFEIVEPREQVIYAVLLLVSVLLILLMIFPVAVHRYLFGQRVKATTVHLGHIVVKVVGIGVGLLICGCVWFVVQVLFGWQIGSLVGGSLMLVTIFLLVILPRLVTPLDTLPQQDR

Crispr_ID: NZ_CP034412_3

• CRISPR_ID: NZ_CP034412_3
• CRISPR_location: 2697647-2697917
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP034412_3

Consensus_repeat	Method
TTTTNCGTTAANAACGTAAAA	CRT

spacers of NZ_CP034412_3

>3.1|2697668|45|NZ_CP034412|CRT
GCCTGCCCCGTAGTAGTGCCCCGAGTGGGCGCTGTTGCAGCGGAG
>3.2|2697734|25|NZ_CP034412|CRT
GCTATGGTCAGGCAGTCAATCCGCC
>3.3|2697780|22|NZ_CP034412|CRT
CAGAGCTCTTCACCGGTGTCAT
>3.4|2697823|26|NZ_CP034412|CRT
TTCCAGCCAAGATCGGCCAATCCAAC
>3.5|2697870|27|NZ_CP034412|CRT
GTTCAGACAGGCAGCAGTAGAGCCAGC

CRISPR arrays and Neighbor proteins around NZ_CP034412_3

CRISPR arrays

The CRISPR arrays of NZ_CP034412_3

>merge|NZ_CP034412|3|2697647-2697917|CRT
TTTTGCGTTAAGAACGTAAAAGCCTGCCCCGTAGTAGTGCCCCGAGTGGGCGCTGTTGCAGCGGAGATTTACGTTAACAACGTAAAAGCTATGGTCAGGCAGTCAATCCGCCTTTTACGTTAAGAACGTAAAACAGAGCTCTTCACCGGTGTCATTTTTAGGTTAAAAACGTAAAATTCCAGCCAAGATCGGCCAATCCAACTCTTACGTTAAGAACGTAAAAGTTCAGACAGGCAGCAGTAGAGCCAGCTTTTGCGTTAAGAACGTAAAA

>NZ_CP034412|3|2|2697647-2697917|CRT
TTTTGCGTTAAGAACGTAAAA	GCCTGCCCCGTAGTAGTGCCCCGAGTGGGCGCTGTTGCAGCGGAG
ATTTACGTTAACAACGTAAAA	GCTATGGTCAGGCAGTCAATCCGCC
TTTTACGTTAAGAACGTAAAA	CAGAGCTCTTCACCGGTGTCAT
TTTTAGGTTAAAAACGTAAAA	TTCCAGCCAAGATCGGCCAATCCAAC
TCTTACGTTAAGAACGTAAAA	GTTCAGACAGGCAGCAGTAGAGCCAGC
TTTTGCGTTAAGAACGTAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP034412.1|WP_138926782.1|2697228_2697537_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138926781.1|2696665_2697025_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138926778.1|2690015_2690258_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP034412.1|WP_138175857.1|2690729_2691416_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187554
NZ_CP034412.1|WP_138927254.1|2705465_2707163_-|FAD-binding-protein	unknown	unknown	gnl|CDD|235758
NZ_CP034412.1|WP_138926784.1|2698450_2699608_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP034412.1|WP_138175843.1|2700461_2702141_-|L-lactate-permease	unknown	unknown	gnl|CDD|224535
NZ_CP034412.1|WP_054821375.1|2702286_2703051_+|(Fe-S)-binding-protein	unknown	unknown	gnl|CDD|223325
NZ_CP034412.1|WP_138175841.1|2704516_2705149_+|lactate-utilization-protein-C	unknown	unknown	gnl|CDD|224473
NZ_CP034412.1|WP_138176151.1|2703068_2704520_+|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl|CDD|224062
NZ_CP034412.1|WP_138176153.1|2692098_2692578_-|hypothetical-protein	unknown	unknown	gnl|CDD|223659
NZ_CP034412.1|WP_138926780.1|2693855_2694992_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|369639
NZ_CP034412.1|WP_054821161.1|2691512_2691974_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_CP034412.1|WP_054821294.1|2695493_2695943_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP034412.1|WP_054821295.1|2694992_2695346_-|bifunctional-3-phenylpropionate/cinnamic-acid-dioxygenase-ferredoxin-subunit	unknown	unknown	gnl|CDD|239604
NZ_CP034412.1|WP_138926787.1|2708297_2709086_-|dethiobiotin-synthase	unknown	unknown	gnl|CDD|234625
NZ_CP034412.1|WP_138926779.1|2692591_2693839_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP034412.1|WP_138926785.1|2699705_2700416_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225097
NZ_CP034412.1|WP_138927255.1|2709082_2710240_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP034412.1|WP_138926786.1|2707384_2708332_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP034412.1|WP_138175857.1|2690729_2691416_+|SDR-family-oxidoreductase	gnl|CDD|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.09517e-50
NZ_CP034412.1|WP_138926787.1|2708297_2709086_-|dethiobiotin-synthase	gnl|CDD|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	5.51031e-47
NZ_CP034412.1|WP_138927254.1|2705465_2707163_-|FAD-binding-protein	gnl|CDD|235758	PRK06263, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	4.51429e-168
NZ_CP034412.1|WP_138926784.1|2698450_2699608_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	8.4776e-71
NZ_CP034412.1|WP_138175843.1|2700461_2702141_-|L-lactate-permease	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	6.19097e-125
NZ_CP034412.1|WP_054821375.1|2702286_2703051_+|(Fe-S)-binding-protein	gnl|CDD|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	9.41752e-52
NZ_CP034412.1|WP_138175841.1|2704516_2705149_+|lactate-utilization-protein-C	gnl|CDD|224473	COG1556, COG1556, Uncharacterized conserved protein [Function unknown].	3.77143e-31
NZ_CP034412.1|WP_138176151.1|2703068_2704520_+|iron-sulfur-cluster-binding-protein	gnl|CDD|224062	COG1139, COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion].	0
NZ_CP034412.1|WP_138176153.1|2692098_2692578_-|hypothetical-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	8.80605e-17
NZ_CP034412.1|WP_138926780.1|2693855_2694992_-|FAD-dependent-oxidoreductase	gnl|CDD|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.30084e-45
NZ_CP034412.1|WP_054821161.1|2691512_2691974_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.64532e-35
NZ_CP034412.1|WP_054821294.1|2695493_2695943_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.80837e-17
NZ_CP034412.1|WP_054821295.1|2694992_2695346_-|bifunctional-3-phenylpropionate/cinnamic-acid-dioxygenase-ferredoxin-subunit	gnl|CDD|239604	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The ferredoxin component contains either a plant-type or Rieske-type [2Fe-2S] cluster. The Rieske ferredoxin component in this family carries an electron from the RO reductase component to the terminal RO oxygenase component. BPDO degrades biphenyls and polychlorinated biphenyls. BPDO ferredoxin (BphF) has structural features consistent with a minimal and perhaps archetypical Rieske protein in that the insertions that give other Rieske proteins unique structural features are missing. CARDO catalyzes dihydroxylation at the C1 and C9a positions of carbazole. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.	8.67654e-40
NZ_CP034412.1|WP_138927255.1|2709082_2710240_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	8.25573e-29
NZ_CP034412.1|WP_138926785.1|2699705_2700416_-|GntR-family-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	9.48981e-32
NZ_CP034412.1|WP_138926779.1|2692591_2693839_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.98942e-28
NZ_CP034412.1|WP_138926786.1|2707384_2708332_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.65727e-47

Protein sequences

>NZ_CP034412.1|WP_138926782.1|2697228_2697537_+|hypothetical-protein
MTEVVQKHEKPKKIHKIGSVVAAACLVVGASFGTAAPAQAATKVLSGSSKHYLSCYRAYSDASRHLVKAGYTSQVHNATCGKKWTWSKGYIYTWKITARTPR
>NZ_CP034412.1|WP_138926781.1|2696665_2697025_-|hypothetical-protein
MIASPDCTFCTFGITTPNGDGCPNPICGLSITIAPAVQDEGCLVTATSNGTGDLNGVVEALADVASCRVADRMIETTPGYPIEVDEPKPVESGWIISEGVARELVEVLFGMGIPYQAAI
>NZ_CP034412.1|WP_054821294.1|2695493_2695943_+|MarR-family-transcriptional-regulator
MHDEELFITVEREFTTTLLRARQTLMRRAKAIHPELQAPGYRILSILVHHDSQQQGFLAESLQLDKATISRLVKQLETQGLITRTADPKDGRAQLVSITDRARDAWYVSGQAQRQRLRDKLEDWSTEDVQRFADLLHRLNDNSDAADAG
>NZ_CP034412.1|WP_054821295.1|2694992_2695346_-|bifunctional-3-phenylpropionate/cinnamic-acid-dioxygenase-ferredoxin-subunit
MRKTNFRTEGEAVSYTVGPVDMIPVGEALKVESDDSGAKEDIAIFHAEDGNFYALQDECTHEVASLSEGWIEDCEVECPLHASRFNLKTGKVLCLPAYVDARTYKVEVIDGMLELHF
>NZ_CP034412.1|WP_138926780.1|2693855_2694992_-|FAD-dependent-oxidoreductase
MGSVHIVGAGVAGFSLAHTLVQAGYAGNITLSDPEGLPYDRPPLSKTLERVNLAPPAWFIEHSVQLQPQRIDQVQTPESEQDWLVLATGTTPRRPQVPGAEHARVIHTAKDAEDLSQKLSFGAFGTQVVVIGAGLIGAEFAAAARQFGAMVTLISNQQVPLVTAFGEPMARQLHEDHRLNGIRVVTGMAERITENSVEVNQESIEADIVVAAIGVEPNLTLADTLGLETHNGIIVDAGMRTSVPQVLAIGDVAREAGARPLRHWDRANEDAALAAATIMGTGAPRRKVPWFWSDRHESHVEVVGDFTAVARTVARHTRQGKIQVLFGLDGQDRLVAASMVDGGLMGRAVRKLIEQEITPPIIDLEDPGITPRNLGRKR
>NZ_CP034412.1|WP_138926779.1|2692591_2693839_-|MFS-transporter
MESNKAVEALRTPTARVGVGWIAAVLIVHIGINVGFFAPIQVLLGLHSEAISPQQKNATLSLVTGVGAVVSMIANPLFGALSDRTTSRFGRRIPWIVAGTLGGALALLLMSTAQTVTVLVLGWALMQAAGNAALAAVLAVVPDKVPVAQRGTVGGLIALAQTLGILVGAGIGMVAASDLVFGYAIVAVVIALCSVPFVLLRQDVVLPASAREEFAWGSFLRSFWINPVRYPDFGWAWLTRFLLYLSSQLILVYLLYFLQDGLNHPEPAAGVLVLSSIYAGFVILSSVVAGKLSDRDGKRKRYVVISSLIVAAAALVMAVAPSFPVAIGGAVLLGLGFGSFLAVDYALLTQVLPHADSRAKDLGVINIANSLPQVFAPLIAWIAVSWLGGYPTLFICAAVVSVAGGLLVRRIKMVP
>NZ_CP034412.1|WP_138176153.1|2692098_2692578_-|hypothetical-protein
MQWIEDAPYLVTYLFFFLGAMIRANTTYWIGRSIAAGVKQTRFQRVLRGPIYLKSQALLARWGVFAVPLSFLTVGVQTAVNATAGITRMPLRRYLPAVIVGCLIWALVYTTVGLAFIYAWIALDWPWLVGIVLLVALVLWLILRRRKRARRVIGPEEIK
>NZ_CP034412.1|WP_054821161.1|2691512_2691974_-|Lrp/AsnC-family-transcriptional-regulator
MKRAQLDELDRKLLRLLSENSRRTNNSLAEELGIAPSTCLARLNQLRDTGVISRFTIEVDPQVLGRELEALIFVRIRPGARHLMSTFAQDMQAKPGVRQLFFLGGADDFVLHVAVRNSADVRQFVLDYLSSNPAVATTQTSLVFEHSHGSAEY
>NZ_CP034412.1|WP_138175857.1|2690729_2691416_+|SDR-family-oxidoreductase
MAEKRRVVIVGGHGKVALLAAPRLVREGFEVHSLIRNPEHITDIRAVGATPVEVDIETASAEELAKTFTGADAVVFSAGAGGGDPERTNAVDYEAAVRTMQAAKQAGVNRYVMVSYARALVDVDNLDPKDSFYPYAKAKHDADEYLRGTSLEYTILGPGALTLEPATKKLRLADSRGRISGHEPAGTEGRTARENVAEMIAYVLAHNAGIRQTVNFFDGDTPMSKIVS
>NZ_CP034412.1|WP_138926778.1|2690015_2690258_-|hypothetical-protein
MQQFDVLVLTALLTIVALGIISAVLVVGYRRTHATEIREDLLAKAQQLGLRVDPAVSNDELRAQVKHARHEARSGKPKAA
>NZ_CP034412.1|WP_138926784.1|2698450_2699608_+|cytochrome-P450
MSASAAPDWDPRSPEVLEDQIAAYDRLRAQCPVAHSEFLGYSVLGHEDALRVLHDPETFSNAVSQRLTVPNGMDPPEHTVYRAVNDRYFTPELMRRFEPVCREVALSLLRELPLHEPIDVIEQLAEVYALRAQSAFLGWPRELEEPLRAWTAKNRTATLAQDRPAMKAIAVEFDGYIRQLLQQRREAGHRAPKDLTTQLLHEQVYGRPLNDEELVSLLRNWTVGELSTIAASVGILANFLATHPEIQTRLREDPSLIGAANDEILRAHAPLIANRRVATRDVEVNGRLIPAGERVTVVWASANRDESVFGDPDEFRLDRDPGLNLLYGAGIHICPGAPLARLELRVLVEELLKRTSSITPAPGAQAPARAHYPGSGYSTLPLQLD
>NZ_CP034412.1|WP_138926785.1|2699705_2700416_-|GntR-family-transcriptional-regulator
MSTKPTPRAYQVVLEAIERDLRTGKLNLGDQLPGERALAEAHGISRASVRDAIRILDVMGVVRTSTGSGPNSGAVIISNPSAGLSQALRLHVAAKGIQVREIVESRILLETWAAQMTPRDPIHAQQVIERTAVLIMRMDDPQLSRDEFHRIDAEFHVLLSSMAGNSVVEAMMESLRHSISDYVASAIPDDATWQPIVKVLRRQHKAIHRAFANNNRERAAHMLEEHINWFYQQTRF
>NZ_CP034412.1|WP_138175843.1|2700461_2702141_-|L-lactate-permease
MFTPSTEPIAGSVAISALVALIPLLTFFVMLAVVKVKAHYAGLSSLLVAIIVAIFGWQMPVGLAINSGVMGVVFGAFPIVWIVVMAIWLYQVTVVSGRFEDLRRVFDVIGGGDVRIQTVLIAFCFGGLLEALAGFGAPVAITATMLLALGLSPLRAASAVLIANTAPVAFGAVAIPITTAGALTGIPAAEIGATVGHQSPVLALFVPTVLVLVIAGWRSMRQTLPVTLVIGISFAIAQWLCATYFSYELTDIVASLVGLGVAVLFLQVWKPKGADEARERILTPEALAKPVDANRNLRPGATWMALFPYVLVILIFGVAKLWRLGVDIPAALAATDVKFGWPGLHGNIVDGNGEAVSSTIYNFNWLSTPGTLLLITGLIVAIVYSKFDDGGKYPIAVGNAIAEIGRTVYNMRFAALTILSVLGLAYVMNLSGQTITIGTWMAGAGGAFAFLSPILGWIGTAVTGSDTSANALFAKLQQTAGVNAGIDPTLLVAANTSGGVVGKLISPQNLAIAATAVKMEGQESVILKKVAGWSVGMLLVLCVLVYLQSTPVLSWMLPH
>NZ_CP034412.1|WP_054821375.1|2702286_2703051_+|(Fe-S)-binding-protein
MRIALFATCIVDAMYPETAKSTVKILERLGHEVIFPAGQACCGQMHMNSGYMPEALPVVENHVQAFERADYDVAVAPSGSCVSSLKHQHGMLAERLGKPDLKSRAAEVAGRTYELSQLLTDVLGITNAAEQLGSYFPHSVTYHPSCHGMRLLKLGDRQLDLLKSVGGITVEELPEADQCCGFGGTFSIKNSDVSSAMLQDKARNIASTGASLCVGGDVSCLMHIGGGLSRNGQKPGTMHLANILASTKEEMVAL
>NZ_CP034412.1|WP_138176151.1|2703068_2704520_+|iron-sulfur-cluster-binding-protein
MPAAGEGNLFADESFPKAAHHELQNTQLRANLRHATHSIRDKRLRVVGELPDWESLRNAGEAIKNQAMARLDERLEEFEKNFTARGGIIHWARDAAEANQIVTDLIKQTGSTEVVKVKSMATQEIGLNEHLETQGIAAFETDLAELIVQLDHDKPSHILVPAIHKNRTEVRDIFLREMPDVDPNLTNEPAKLAEASRKHLRKKFLSTKVAISGANFALADTGTLGVVESEGNGRMCLTLPETLITVMGIEKVLPSWQDIEVFMQLLPRSSTGERMNPYTSLWTGVTENDGPQNVHLVLMDNGRTRALSDRFGRSALNCIRCSACMNVCPVYERTGGHAYGSTYPGPIGAILSPLLTGIEAEENNSLPYASSLCGACFDACPVKINIPEILVHLRGEDVDSQRGKKLLPTQMDLLMKGGSWALGKGRNLDLLEKGLPLGKLAAGRDKKIKRLPGIAAGWTASRDIPAPPSKSFRDWWKSEKEGK
>NZ_CP034412.1|WP_138175841.1|2704516_2705149_+|lactate-utilization-protein-C
MSAKEEILGRIRTALADNPHVEPVVRDYRTTSQLSETEVIELLVDRLVDYKAGVDVIEAEQIATHVAAKLATARSVVYPHGLDTGWLQQLPESIERRIDAPGHALDIPVLDETSAVVTSSAVSIAESGTIILDGEPDQGRRAISLVPDHHVCIVPVSTIVQLLPEAMPRMDVTRPQTWISGPSATSDIELERVEGVHGPRTLDVLIVRGL
>NZ_CP034412.1|WP_138927254.1|2705465_2707163_-|FAD-binding-protein
MLVIGTGGSGLRAAIELAELGVDVLAVGKRPRHDAHTSLAAGGINAALGTMDAEDSWQQHAADTIKESYYLANPHTVQIVAQGAAEGIADLERYGMGFAREEDGRISQRFFGAHTFRRTAFAGDYTGLEIQRSLVRRSEQLQVPILDTVYITDILTHDNRVFGAYGFDVNNGTRYLIHADAVILAAGGHNRIWRRTSSRRDENTGDSFRLAVEAGARLRDPELVQFHPSGIIEPENAAGTLISEAARGEGGILRNGLGERFMERYDPQRMELSTRDRVALAAYTEIKEGRGTKKGGVWLDISHLPRQLIMERLPRVYQTMLEVQMLDITREPIEIAPTAHYSMGGVWVRPEDHSTHVEGLYAIGEASSGLHGANRLGGNSLIELLVFGRIVGRAAAEYSAGLESHTRSAAAVTRARSELERLLAADGQENVRSLQRAIRDMMTECAGVVRDEAGLLEGLRRLDEIEARMANVGIHPDIAGFQDLAHAYDLKSAALSARATLEAALERRETRGCHNRSDYPEQDPQLQVNLVWSPHGGVVRESIPPVPAEISELIGEVDTAGKLVE
>NZ_CP034412.1|WP_138926786.1|2707384_2708332_+|LysR-family-transcriptional-regulator
MNLDQLKSFLTVADLGHFTRAAEQLHLAQPSLSRQIATLESELGSQLFHRARGNITLTPAGEALVPLASRMLADADRIRHQMQELAGLRAGRVRLGAPPSMCISLVAMVLGEFHRRYPGIELHLSEAGSRLLLEQLSAGQLDLALVVASEHEPAAFESLDDIPLLSEELMVIAAKAGQLPAGQGPLSLAQLAPVPQIVFSPSYDLRAATMQAYRSCNLEPNVVLEGGEMDAVLRFVQLGLGVAVVPATVLLDRSEFHTRRLEQPSLTRTISLAHRKDVGLTRAAAAMQQMITATAAQLAGRSPAINALAAPGAQR
>NZ_CP034412.1|WP_138926787.1|2708297_2709086_-|dethiobiotin-synthase
MSGDAARILAVTGTDTEVGKTVVTAVLAAAALQRGHRVAVYKPTQTGVGPGEEGDVQAVARWLSHPAQLTVAEGVRLAPAMAPLDALGQEARRRPSGGAGSLPSLQEHVRRVGELARTHQVVLVEGAGGLLVKLTQQQQTLADLARELHARPVLVTRPDLGTLNHTELTLEAASQRGLREGLLVMGSWPGQPQALHEVNRANLRGLAANFGWTWAPGPLAGVVRQGAGTLTARLHAAGQKIAQTGELWEARVSAAHRVRPGR
>NZ_CP034412.1|WP_138927255.1|2709082_2710240_-|cytochrome-P450
MPGPPATTTRRAPLGGNLHRAYPPQITERYRIIEDPQQVRRILLRPELFTPDNALLTAIDLAPSALRILAAEKFFLPPVLASASGQEHRRVRRIVAGFFSPAKVAAQRGFVQRRAREICEDLAAGTEREPVDLSARLAAPIPAEVMQRLSGVPVPPADLLKRFSRHSLELFWGWPDHQRQLELARTAAQFHAWLRHSVLQAIAAGDGNLYAELHREGVDADRIRSLGYFLTIAGQETTALLIHTVLHTALDRGRWEQCAHNPHTAAQLVGAVLAAQSSVPTWRRVVARDTVCGGEQFLAGQQLVLQLSGGQLGREQDDSLAFGLGVHRCLGAGLARMQAEEVLRTAAQQLPGLTLTEPETPWLHLLSFQAPLTVPARLAAAGVRA

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP034412_2	2.9|2655771|34|NZ_CP034412|CRT	2655771-2655804	34	NZ_CP034412.1	3014086-3014119	0	1.0
NZ_CP034412_2	2.9|2655771|34|NZ_CP034412|CRT	2655771-2655804	34	NZ_CP034412.1	3014140-3014173	0	1.0

1. spacer 2.9|2655771|34|NZ_CP034412|CRT matches to position: 3014086-3014119, mismatch: 0, identity: 1.0

agttgcatcagcctgagcgtccgcaccggactca	CRISPR spacer
agttgcatcagcctgagcgtccgcaccggactca	Protospacer
**********************************

2. spacer 2.9|2655771|34|NZ_CP034412|CRT matches to position: 3014140-3014173, mismatch: 0, identity: 1.0

agttgcatcagcctgagcgtccgcaccggactca	CRISPR spacer
agttgcatcagcctgagcgtccgcaccggactca	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP034412_3	3.2|2697734|25|NZ_CP034412|CRT	2697734-2697758	25	MN693593	Marine virus AFVG_25M494, complete genome	7647-7671	3	0.88
NZ_CP034412_3	3.4|2697823|26|NZ_CP034412|CRT	2697823-2697848	26	NZ_CP011404	Lactobacillus salivarius str. Ren plasmid pR1, complete sequence	167724-167749	4	0.846
NZ_CP034412_3	3.4|2697823|26|NZ_CP034412|CRT	2697823-2697848	26	NZ_CP020859	Lactobacillus salivarius strain ZLS006 plasmid unnamed1, complete sequence	186630-186655	4	0.846
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	80061-80088	5	0.821
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	80169-80196	5	0.821
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	107955-107982	5	0.821
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	108063-108090	5	0.821
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP028567	Aeromonas hydrophila subsp. hydrophila strain WCHAH045096 plasmid pMCR5_045096, complete sequence	148573-148600	5	0.821
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	126281-126308	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP041205	Rhizobium sp. NIBRBAC000502774 plasmid pMK-2, complete sequence	20257-20284	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP041205	Rhizobium sp. NIBRBAC000502774 plasmid pMK-2, complete sequence	20299-20326	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP053858	Rhizobium pusense strain 76 plasmid pR76, complete sequence	458299-458326	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	590643-590670	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP023496	Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence	165152-165179	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP023496	Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence	166691-166718	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP023496	Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence	140583-140610	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP023496	Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence	142125-142152	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	79185-79212	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	79965-79992	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	80085-80112	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	80193-80220	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	107931-107958	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	108039-108066	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP031267	Staphylococcus warneri strain 16A plasmid unnamed3	108159-108186	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NC_031122	Gordonia phage Eyre, complete genome	6546-6573	6	0.786
NZ_CP034412_2	2.6|2655603|28|NZ_CP034412|CRT	2655603-2655630	28	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	466022-466049	8	0.714
NZ_CP034412_2	2.5|2655549|34|NZ_CP034412|CRT	2655549-2655582	34	MG030346	Proteus phage PM87, complete genome	11826-11859	11	0.676
NZ_CP034412_2	2.5|2655549|34|NZ_CP034412|CRT	2655549-2655582	34	MN840486	Proteus phage P16-2532, complete genome	11753-11786	11	0.676
NZ_CP034412_2	2.5|2655549|34|NZ_CP034412|CRT	2655549-2655582	34	MN604053	Escherichia phage E21, complete genome	25793-25826	11	0.676
NZ_CP034412_2	2.5|2655549|34|NZ_CP034412|CRT	2655549-2655582	34	CP059058	Proteus phage ASh-2020a, complete genome	3400-3433	11	0.676
NZ_CP034412_2	2.9|2655771|34|NZ_CP034412|CRT	2655771-2655804	34	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	182974-183007	11	0.676
NZ_CP034412_2	2.9|2655771|34|NZ_CP034412|CRT	2655771-2655804	34	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	177934-177967	11	0.676

1. spacer 3.2|2697734|25|NZ_CP034412|CRT matches to MN693593 (Marine virus AFVG_25M494, complete genome) position: , mismatch: 3, identity: 0.88

gctatggtcaggcagtcaatccgcc	CRISPR spacer
cctatggtcgggcattcaatccgcc	Protospacer
 ********.**** **********

2. spacer 3.4|2697823|26|NZ_CP034412|CRT matches to NZ_CP011404 (Lactobacillus salivarius str. Ren plasmid pR1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccagccaagatcggccaatccaac	CRISPR spacer
gtccagccaagataggccaatctaat	Protospacer
 ************ ********.**.

3. spacer 3.4|2697823|26|NZ_CP034412|CRT matches to NZ_CP020859 (Lactobacillus salivarius strain ZLS006 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

ttccagccaagatcggccaatccaac	CRISPR spacer
gtccagccaagataggccaatctaat	Protospacer
 ************ ********.**.

4. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 5, identity: 0.821

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcggcgtcggcgtcggcatcagcatca	Protospacer
 **.****************.*** * *

5. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 5, identity: 0.821

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atctgcgtcggcgtcggcatcagcatca	Protospacer
 ** ****************.*** * *

6. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 5, identity: 0.821

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atctgcgtcggcgtcggcatcagcatca	Protospacer
 ** ****************.*** * *

7. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 5, identity: 0.821

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcggcgtcggcgtcggcatcagcatca	Protospacer
 **.****************.*** * *

8. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP028567 (Aeromonas hydrophila subsp. hydrophila strain WCHAH045096 plasmid pMCR5_045096, complete sequence) position: , mismatch: 5, identity: 0.821

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
ataaccgtcggcgtcggcatcggcctga	Protospacer
 * * ***************..******

9. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
tacagcgtcggcgtcggcatcagcgcct	Protospacer
* ******************.*** .  

10. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP041205 (Rhizobium sp. NIBRBAC000502774 plasmid pMK-2, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcagcgtcggcatcggcatcagcgtcg	Protospacer
 ***********.*******.*** * .

11. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP041205 (Rhizobium sp. NIBRBAC000502774 plasmid pMK-2, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcagcatcggcgtcggcatcagcgtcg	Protospacer
 *****.*************.*** * .

12. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP053858 (Rhizobium pusense strain 76 plasmid pR76, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atccgcgtcggcgtcggcatcagcatcc	Protospacer
 ** ****************.*** *  

13. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcagcatcggcgtcggcatcagcatcg	Protospacer
 *****.*************.*** * .

14. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP023496 (Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcggcgtcggcgtcggcatcagcatct	Protospacer
 **.****************.*** *  

15. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP023496 (Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcggcgtcggcgtcggcatcagcatct	Protospacer
 **.****************.*** *  

16. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP023496 (Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcggcgtcggcgtcggcatcagcatct	Protospacer
 **.****************.*** *  

17. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP023496 (Staphylococcus simulans strain FDAARGOS_383 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcggcgtcggcgtcggcatcagcatct	Protospacer
 **.****************.*** *  

18. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
gtcagcgtcggcatcggcatcagcatct	Protospacer
 ***********.*******.*** *  

19. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atcagcgtcggcatcggcatcagcatct	Protospacer
 ***********.*******.*** *  

20. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atcagcgtcggcgtctgcatcagcatct	Protospacer
 ************** ****.*** *  

21. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atcagcgtcggcgtctgcatcagcatct	Protospacer
 ************** ****.*** *  

22. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atcagcgtcggcgtctgcatcagcatct	Protospacer
 ************** ****.*** *  

23. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atcagcgtcggcgtctgcatcagcatct	Protospacer
 ************** ****.*** *  

24. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP031267 (Staphylococcus warneri strain 16A plasmid unnamed3) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
atcagcgtcggcatcggcatcagcatct	Protospacer
 ***********.*******.*** *  

25. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NC_031122 (Gordonia phage Eyre, complete genome) position: , mismatch: 6, identity: 0.786

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
ctgggcgtcggcgtcggccttcgcctgc	Protospacer
.* .************** ** ***** 

26. spacer 2.6|2655603|28|NZ_CP034412|CRT matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.714

ttcagcgtcggcgtcggcattagcctga	CRISPR spacer
aacagcgtcggcgtcggcataaggaaac	Protospacer
  ****************** **   . 

27. spacer 2.5|2655549|34|NZ_CP034412|CRT matches to MG030346 (Proteus phage PM87, complete genome) position: , mismatch: 11, identity: 0.676

ctgagcatccgcaccggactcagtatcagcgtcg	CRISPR spacer
ggagtcatacgcatcggactcagtatcagagatc	Protospacer
  .. *** ****.*************** * . 

28. spacer 2.5|2655549|34|NZ_CP034412|CRT matches to MN840486 (Proteus phage P16-2532, complete genome) position: , mismatch: 11, identity: 0.676

ctgagcatccgcaccggactcagtatcagcgtcg	CRISPR spacer
ggagtcatacgcatcggactcagtatcagagatc	Protospacer
  .. *** ****.*************** * . 

29. spacer 2.5|2655549|34|NZ_CP034412|CRT matches to MN604053 (Escherichia phage E21, complete genome) position: , mismatch: 11, identity: 0.676

ctgagcatccgcaccggactcagtatcagcgtcg	CRISPR spacer
ggagtcatacgcatcggactcagtatcagagatc	Protospacer
  .. *** ****.*************** * . 

30. spacer 2.5|2655549|34|NZ_CP034412|CRT matches to CP059058 (Proteus phage ASh-2020a, complete genome) position: , mismatch: 11, identity: 0.676

ctgagcatccgcaccggactcagtatcagcgtcg	CRISPR spacer
ggagtcatacgcatcggactcagtatcagagatc	Protospacer
  .. *** ****.*************** * . 

31. spacer 2.9|2655771|34|NZ_CP034412|CRT matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 11, identity: 0.676

agttgcatcagcctgagcgtccgcaccggactca	CRISPR spacer
tcaaccatcagcctgagcgtgcgcagcggcgaga	Protospacer
     *************** **** ***    *

32. spacer 2.9|2655771|34|NZ_CP034412|CRT matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 11, identity: 0.676

agttgcatcagcctgagcgtccgcaccggactca	CRISPR spacer
tcaaccatcagcctgagcgtgcgcagcggcgaga	Protospacer
     *************** **** ***    *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1198514 : 1206648	7	Anomala_cuprea_entomopoxvirus(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP034412|1198514:1206648|DBSCAN-SWA
CATGAGTATCCCCGCACTGAGCATCAGATCGCTGGCCAAGCAGTTTGGCCCCAAGGTGGCGGTCAACGACGTCAGCCTGGACGTCCCGGCCGGTTCCTTCTTTGGACTGGTCGGCCCGAACGGCGCCGGCAAGACCACCATGCTGTCCATGGCCACCGGGCTGCTGCGCCCGGATGCCGGCAGCGCTGCGGTGCACGGGGTGGACGTGTGGGCCCAGCCGCGCGAGGCGAAGTCGATGATGGGGGTGCTGGCCGACGGGGTGCGCCAGTTCGACCGGCTCACCGGACGCCAGCTGGTCACCTATTCGGGGCTGCTGCGCGGGATGGAGCGCGAGGAGGTCACCACCCGCACCGAGGACCTGCTGCGGGTCATGGACCTGGTCAACGACGGGGACAAGCTGGTGGTGGACTACTCCGCGGGGATGACCAAGAAGATCTCGCTGGCCACCGCGATGATCCACTCGCCGAAGCTGCTGGTGCTCGATGAGCCCTTCGAGGCGGTGGACCCGGTCTCGGCGGCGAACATCCGCGACATCCTGAACGAATACGTGAAGTTCGGCGGCACCGTGATCGTCTCCTCCCACGTGATGGACCTGGTGCAGCGCATGTGCTCGCACGTGGCCGTGATCGCCGACGGGGTGCTGCGCGCCTCGGGCACCGTGGATGAGGTGCGCGGCGGGATGAGCCTGGAGGAGCGCTTCGTGGACCTGGTCGGCGGACGGGCACAGGGCGGAGGGCTGTCGTGGTTGCGCACATCCTCAAACTGAAGCTGACCCTGCTGCGCAACGGTTTCCGGCGCAGCACCTGGCAGCTGGTCGGAGTGATCATCGGTACGCTCTACGCCCTGGGCGTGGTGGCGATGCTGATCCTGGCCGCCTGGTTCTCCGCGGACCTGCAGTGGCTGAGCTACATTTCCATCCTGGCCAGCTCGCTGGTGGTGATCGGCTGGGCGATTGTCCCGCCGCTGCTGACCGGCGTGGACCTGACCCTGGAGCCGCAGCGCTTCGTGCACTTTGGCATTGAGCCCAAGACGCTGGGCCGGGCGCTGGTGCTGGCCGGGTTCGTCTCCATCCCGGCGCTGATCACGGTGCTGGCGATGGCCGGGTTCAGCGTGCTGTGGCGCCTGGATCCGGGTGTGCTGCTGCTGGCGCTGGTGGCGAACCTGGGCACCGCGGTGCTGGCGGTGTTCGGCTGCCAGTACCTGACCATCCAGGCCACCGCGCTGCGCTCCAAGCGCCGCTTCCGCGAGGCCACGTTCCTGATCTTCTTCCTGCTGCTGGTGAGCCTGGGGCCGATCATCGGGATGCTCACCGAGGCGGCGACCAGCGCCCTTGACTGGATCGACCCGGTCGCCACGGTGTTGGCCTACACCCCGTTCGGCACCCTGGGCGCGGTCGCCCCGGCCGCCGCCGAGGGCGCGTGGCTGGCCGCGATCGGCCACCTGCTCTACGGCCTGGTGTGCCTGGCGGTGCTCTACTGGCTGCTGCTGCGGGCCACCGCGAACGCCGTGGTCACCGCGCCGGCCCCGCAACGCGCCGCCTCGGCCAAGGGGCTGGGCCCCTTCAAGTGGATGCCGCCCACCCCGTGGGGTGCGGTCGCCGCCCGGGCGCTGGTGTATTGGCTGAAGGACCCGCGCTACGCGATCGGCGTGCTGATGGTCCCGGTGCTGCCGGTGATCTTCTACTTCGCCGGCTCCCAGTCCGGCAGCTACGCGATGATGTTCCTGCTCGGCCCGATCTTCGGGATCCTGATGGGCTTTTCCATCTCCGCCGACGTCTCCTACGACAACACCGCGTTCTCCCTGCACGTGCTCACCGGGGTGCGGGGCCGCGATGACCGGATCGGGCGCATGCTCGCCTGCCTGCTGGTGGGCCTGGTGCCGGTGCTGCTCGGGGCGATCCTGCCCGGGGCGCTGACCAACCAGTACTGGCGCATCCCGGCCGATGTGGGCCTCTCGCTCGGTGCGCTGCTGGTGGCCCTGGCGATCTCCTCGGTGGTCTCGGCCCGCTACACCTACGCGGTCCCGTTGCCGGGGGAGAACCCGATGAAGACCCCGCCGGGCAACGGGGTGCGCGTGGCGCTGACCCAGCTGCTGACCTTTGGCGGGATGGGGCTGCTCTTGCTGCCGCTGGTGATCCCGTACCTGTTTGCGATCTTCGGCCGTATCCAGCCGCTGGGCTGGGTGACCCTGGCCGGCGCATTCGTCTACGGCGGGATCCTGCTGTTGATCGGTGTGCGGGTGGGCGGCAAGTGGATGGATGCCCGCCTGCCGGAGCTGATGCAGGCGGTGCTGCTGAACAAGTAGCGGCCTTGACGGCCATGGCGCCTCACCCAAGCCCCGGGCCGCCGGTGCTGGATCATCTCCAGCACCCGGCTACCGGGGCTTTGCCATGTCCGCAACCCCCTGCCGGTGCCCGGAACTTCACACGGTGTTCAAAGCCATCCGCGGTGCCCTGAAAGTCGGCAGGTCAGCCCGCTAATCGAGCGGATTCCCGGGGCTGCGGCGGACCGCTTGGGCGTGCTGTGGGGGCTTGGGTGGAGCGCGAAAAGTACTAGACTGGATGCCATGGTTGAAGAGTCACAAGAAACCCGCGGCGGAACAGCAACAATCGAGCGGACCGAGACGCAGCAGAACGTTGAGGCCGGCGATCACGAGCGCTTCGCACACTATGTGCGCAAGGAAAAGATCATGGAATCGGCCCTGTCCGGGGAACCGGTGATCGCCCTGTGCGGCAAGGTCTGGACTCCCGGCCGCGACCCCAAGAAGTTCCCGGTCTGCCCGGAGTGCAAGGAAATCTACGAATCCATGCAGGGCGACTAACCGACCCTGCCTTCACGCCCGGCAGCCGCACGGCTGCTGGGCATAGATTCGTGGTCCGCGCCGGGAGAGGATAGATGACCGACACACTTTTCGACATTGGTGACAAGCTTCCGCTGGAAGACAAGCTGCCGGTGGCATATCCGGAACGCGCGGCCTGGGGCACCGGGCCGAAGCTGCGCGCCTGGCAGGCCGAGGCGCTCGCCCTCTACTTCGACACCGAACCCAAGGACTTCCTGGCGGTGGCGACCCCCGGCGCCGGTAAGACCACGTTCGCGCTGCGCCTGGCCAAGGTGCTGGTGGACTCCAAGAAGATCAACCGGATGATCGTGGTCGCGCCCACCGACCACCTGAAGAAGCAGTGGGCCGACGCGGCCGGCCGTGTCGGGCTGGCGCTGGACCCGAACTACAAGAACTCCGATGGCCGCCATGGCGATCACTACCTCGGGGTCGTGGTCACCTACGCGCAGGTCGCCCAGAAGCCGGCCGTGCACCGGGCCAAGACCGAGGACGCGCGCACCTTGGTGATCATGGACGAGGTCCACCACGCCGGTGACGCCCTGTCCTGGGGCGATGGCATCCGCGAGGCCTTCGAGCCGGCCACCCGCCGCCTGGCGCTGACCGGTACCCCGTTCCGTTCGGACACCGCCCCGATCCCGTTCGTGCAGTACACCGACGAGGGGGACGGGATCCGCCGCTCCAAGGCCGACTACACCTACGGCTACGGCAACGCCCTGACCGACCACGTGGTGCGCCCGGTGCTGTTCATGGCCTACTCGGGCAACATGCGCTGGCGCACCGCCGCCGGCGAGGAAATGGAGGCCCAGCTCGGTGCCGGGGCCACCAAGGACATCACCGCCCACGCCTGGCGCACGGCGCTGGACCCGGCGGGGGACTGGATCCCCTCGGTGCTGCGCGCCGCTGACCGCCGCCTGTCCGAGGTGCGGCGCACCGTGAAGGACGCCGGCGGGCTGGTGATCGCCACCGACATCGATGACGCCAAGGCCTACGCCCAGCAGCTGGAGGCAATCTGCGGGCAGAAGGTCACCACGATCCTCTCCGATGACCCCACCGCCTCGCAGAAGATCGATGAGTTCTCCGAAGGAGACTCACGCTGGATGGTGGCGGTGCGCATGGTGTCCGAGGGCGTGGACGTGCCCCGGCTGTGCGTGGGCGTGTACGCCACCTCAACCTCGACCCCGCTGTTCTTCGCCCAGGCCGTCGGCCGCTTCATGCGAAGCCGCAAGCGCGGTGAAGTGGCCAGCGTGTTCCTGCCCTCCGTGCCGATCCTGATGGCCCTGGCCAATGAGATGGAGGTCGAACGCGACCACGCGCTGGACCGCGAAGGCTCCAAGGTGGAGGACGGGCTGGATGACGCGGCCCTGGAGGAAGCCAACCGTGAGGAGAAGGCCAGCGACGAGCTGGTGCGCAACAAGTTTGAGGCGCTGAACTCCCAGGCCTCGTTCGACCGTGTCCTCTTTGACGGCGGCGAGTTCGGCACCGGCGCGGACATCGGCAGCGATGAGGAGCTCGGCTTCCTGGGGATCCCCGGGCTGCTGGAGCCCGAACAGGTCTCGGCGCTGCTGCGCGAACAGCAGAGCAAGCAGATCAAGGGCGGGGCCTCCAAACCCGCCCCGGTTTCCGACCACCGCCAGCTGATGGACCTGCGCAGCCAGCTGTCCAAGAACGTTTCGGCGTGGGCGGCGCGCACCGGCACCCCGCACGCGCAGATCCACACGAAGCTGCGCAGCGTGTGCGGTGGCCCGGCCGTGCCGCAGGCCAACGCGGACCAGCTGCGCGCCCGCATTGAGAAGCTGCAGGACTGGTTCGTCGGGCGCAAGTAGCCAGCGGTGACCGCAGTCCCGGTAGGAGCGGAACGCCGCAACCAAACCAAAGAGGAAGAGGCCGCCACGGCAGCCTCTTCCTCTTTGACAATGCCCGTGTTCGGACCCGGTTTCTAGCCCAGGGTCAGGACGGTGACCCCGGATTCACGCAGTTCACTGTAAAGGCTCGGCAGGTTCTCGGGGGAGACCGCCGCGGTCAGCGGGGTGATCACGGTGGTGGCAAAGCCGGCCTTGGCCGCATCCAGCGCGGTGGCGCGCACGCAGTGGTCGGTGGCGATGCCCACCACGTCCACCGCGGTCACCTGCCGCTGCTTTAGCCAGTCCTCCAGCAGCGGACCGGATTCGTCCTCCAGATCCGCGGCCGGATTCAGCAGCCGGGCCTCGAAGCCCGAATAGCCATCCGAATACCGGCCCTTGGCGAAGTGGCCGTCCACCCCCAGGTCGGCGATCTGTGGATGCAGGGCGGCCCCGGGAGTCCCGGCCACGCAGTGCACCGGCCAGGTGTCCACGTAGTTCGGGTTCTTAGAGAAATGCCGGCCCGGATCGATGTGCCAGTCCTGGGTGGTGGCGATCGCGGTGTAGGAGTCGCGGCGTTCGGCCACATCCGCGGCAATGGCCGAGGCAACGGCATTGCCGCCCTTCACGCCCAGCGGGCCGCCTTCGCAGAAGTCCGGTTGTACGTCAATGATCAGCAGTGCGCGGGACATAGTGCTTCCTATTCATTCACGAGGATCGTGGGGATCACCGGTTCACCGCGCTGCAGTTTGCGGGCGATGCCTGGCATCTCCTGGATCGAGGCGTGGTGCCGCTGGCGGGCCAGCTGCACGCCGGAGGCTGAGACATACTTTTCGTCAATCTCACCATGCGTGACCAGCGGGACGGTTAGCAAGCGTTCCGGGCCTTCGGTGGTGTGTTCACCCAGTACAACGATCTCGTTGACCGCACGGTTCCGCTCATTGAGCTGACGCACGCCGCTCTTGCGTCCGCCGGTGCTGGCCTTGTTGGTGGCGGCCTTGGCCACCGGGATCCATTCGCCGGAGGTGTCCTGACGGGCCACCAGCTTGTAGACCATGGAGGCGGTGGGGTGCCCGGAACCGGTGACCAGTGCGGTGCCCACCCCGTAGGAGTCCACCGGGGCGCTGGCCAGGGCGGCGATCGCGTACTCGTCCAGGTCGCTGGTCACGGTGATCTTGGTGTTCCAGTTGCCCAGGTCATCGAGCAGCTCGCGCACCCAGGTGGCCTGTTGGACCAGGTCCCCGGAGTCCAGCCGGACCGCACCCAGTTCGGCGCCGGCGACCTCCACCGCGGTGCGCACGCCCTGCTCGACGTCGTAGGTGTCCACCAGCAGCGTGGTGTCCACGCCCAGGGCATCGACCTGTGCCTGGAACGCCTCGCGTTCGCTTTCATGCAGCAGGGTGAAGGAGTGGGCGCTGGTGCCCACGGTCGGGATGTCGTAGCGGGCCCCGGCCTCCAGGTTGGAGGTGGAGTCAAACCCGGCGATGGCGGCGGCGCGCGCCGCGGCCACGGCGGCCTCCTCGTGGGTGCGCCGCGAGCCCATCTCGATGCAGGGGCGCTCGCCGGCGGCGGCGATCATGCGAGAGGCGGCGGAGGCGATGGCCGAATCGTGGTTCAGCGTGGAGAGCACGAAGGTCTCGATGACGCAGGCCTCGGCGAACGTGGACTCCACGGTCAGCAGCGGCGAGTTGGGGAAATAGAGCTCACCTTCGGCGTAGCCGGTGATGTTGCCGGTGAACTTGAAGTTCTCCAGGTAGTCCAGGGTCTCCTTGTTCACGACCTTGTTGTCGGACAGGAACTTCAGCTGTTCGTCCTCGAAGCGGAAGTTCGCCAGCCCCTCCAGCAGCCGGCCGGTGCCGGCGACCACTCCGTAGCGACGTCCATCCGGCAGGCGGCGGGCGAAGGCCTCGAACACGCTGGGACGGTGCGCGGCCCCGGACGCCAGTGAGGCCTGCAGCATGGTCAGCTCATAGTGGTCGGTAAAGAGGCTGGTGAGCATGCGGTGCTCCTGTGTAGTCGGGGACAAACCAAGACTTACTGTATCCCGCTTCAAACCGTGGTGAGACATCACCCCGGTGCCAGGTGCGGGCGAGTCCCGGACACGCCGGCGCATTGCCCTGCACTGGATTCGCCTGAGTCGGTTCCGTTGCCGGGTTCCAGCAAGAGAGGCACGGAAATGGGAGTCGAGTGGGCCAGCACCAGCGTCTATGGGGCTGGGGCCGGCCCGGGGACGGCGGAGCCGTAGAGCCTGCTGTTCGGGCTTGAAGTCGCCATGTCGCGCTGGTATTTTCAGCAAAAAGCGGGGTTCGGATGATGCGGACCGGTGAAGCGGCCGGGAGCTGTACGCGGTGCGCGTCTGCGGCGCGGGCACCAACCGTGCGGATCCGGCATCTCAGGGGCACCCCTGAGACGATCGACAACGAGAAACGAGTGGCAAGCGTGTACGAATCTGGCACCGGTGAAGGCTCCCTGTCACAGGACGCACTCCTTGGAAATGCGAAGGGTGCACCGCGGCTGGCCGCGCAGCGCAGGGAGGTCAACGGTGCCCACAGTTTCTCCCAGGCCGCGCAGCGCGTGGTGGACTACCTGAACCACCACACCCCTTTAACTGATTGGTCGGTCTCGCGGATCACCGACGGGTACCAGGTGCACCTGCACGTTCACCATGATCACCTGATCAACGTGGGGGACCGGATGGACTGGGGCGAAACCTTTTGTCGGCGCATGGCGGCGGGCGCCGCACACGTGGTCCCCGACGCCAAGACCCACCCGCAGTATGCGGATTTGCAGGTTGCCCGCAAGATCGGGGCGTATGCCGGCTATACGATCGGTGATGACAATGGACAGCCCTTCGGCGTGCTGTGCGGGGTGCGCAGCCAACCGCTGGAGGCTGACGAGTCCGTGGACGAGGAACTGCTCAAGGTCTTCAGTGACCTGCTTTCCTCCCAGCTGGAACTCTCCCGCGGCTTTGACCGGGACCGGCGGGCCCTGGAAATCGCGAAGGCACAGGCACACCGCGATGCCCTGACCGACTTGCTGAACCGTCGCGGCTGGGACGCGATTCTTGCCGACGCCCAGGCACGGGTCAACGCCTTTGGGGATCTGGTCGCCGTGGCCGTGCTCGACATTGACGGATTGAAGGCCCTGAACGATTCGCAGGGTCACACGGCGGGGGATCAGTTGATCCAACGCGCGGCCCGGGCCCTGCGCGACGCCTCCTCGCGCTCCCACCGGATTGCGCGCTACGGGGGAGATGAGTTCGTCATCCTGGCCAACGGGATCCCTTCCGCGCGGCTGGAGCAGCATTTCGCCGTGTTCCGCCAGGCTTTGGAAACGGCCGGGGTTGCGGCGTCGCTTGGCTACGCCGCCTCGGTGCCCGGGGATTGCTCGGTGCAGCAGGCATTCATGGAAGCCGACCGGCAAATGTACCTGGACAAGCAGCGCCGCCGGGCCCGATAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP034412|1198514:1206648|1201407_1203174_+|WP_138925971.1|DBSCAN-SWA
MTDTLFDIGDKLPLEDKLPVAYPERAAWGTGPKLRAWQAEALALYFDTEPKDFLAVATPGAGKTTFALRLAKVLVDSKKINRMIVVAPTDHLKKQWADAAGRVGLALDPNYKNSDGRHGDHYLGVVVTYAQVAQKPAVHRAKTEDARTLVIMDEVHHAGDALSWGDGIREAFEPATRRLALTGTPFRSDTAPIPFVQYTDEGDGIRRSKADYTYGYGNALTDHVVRPVLFMAYSGNMRWRTAAGEEMEAQLGAGATKDITAHAWRTALDPAGDWIPSVLRAADRRLSEVRRTVKDAGGLVIATDIDDAKAYAQQLEAICGQKVTTILSDDPTASQKIDEFSEGDSRWMVAVRMVSEGVDVPRLCVGVYATSTSTPLFFAQAVGRFMRSRKRGEVASVFLPSVPILMALANEMEVERDHALDREGSKVEDGLDDAALEEANREEKASDELVRNKFEALNSQASFDRVLFDGGEFGTGADIGSDEELGFLGIPGLLEPEQVSALLREQQSKQIKGGASKPAPVSDHRQLMDLRSQLSKNVSAWAARTGTPHAQIHTKLRSVCGGPAVPQANADQLRARIEKLQDWFVGRK
>NZ_CP034412|1198514:1206648|1201078_1201333_+|WP_054821750.1|DBSCAN-SWA
MVEESQETRGGTATIERTETQQNVEAGDHERFAHYVRKEKIMESALSGEPVIALCGKVWTPGRDPKKFPVCPECKEIYESMQGD
>NZ_CP034412|1198514:1206648|1198514_1199279_+|WP_138173052.1|DBSCAN-SWA
MSIPALSIRSLAKQFGPKVAVNDVSLDVPAGSFFGLVGPNGAGKTTMLSMATGLLRPDAGSAAVHGVDVWAQPREAKSMMGVLADGVRQFDRLTGRQLVTYSGLLRGMEREEVTTRTEDLLRVMDLVNDGDKLVVDYSAGMTKKISLATAMIHSPKLLVLDEPFEAVDPVSAANIRDILNEYVKFGGTVIVSSHVMDLVQRMCSHVAVIADGVLRASGTVDEVRGGMSLEERFVDLVGGRAQGGGLSWLRTSSN
>NZ_CP034412|1198514:1206648|1205499_1206648_+|WP_138925973.1|DBSCAN-SWA
MMRTGEAAGSCTRCASAARAPTVRIRHLRGTPETIDNEKRVASVYESGTGEGSLSQDALLGNAKGAPRLAAQRREVNGAHSFSQAAQRVVDYLNHHTPLTDWSVSRITDGYQVHLHVHHDHLINVGDRMDWGETFCRRMAAGAAHVVPDAKTHPQYADLQVARKIGAYAGYTIGDDNGQPFGVLCGVRSQPLEADESVDEELLKVFSDLLSSQLELSRGFDRDRRALEIAKAQAHRDALTDLLNRRGWDAILADAQARVNAFGDLVAVAVLDIDGLKALNDSQGHTAGDQLIQRAARALRDASSRSHRIARYGGDEFVILANGIPSARLEQHFAVFRQALETAGVAASLGYAASVPGDCSVQQAFMEADRQMYLDKQRRRAR
>NZ_CP034412|1198514:1206648|1203287_1203881_-|WP_138925972.1|DBSCAN-SWA
MSRALLIIDVQPDFCEGGPLGVKGGNAVASAIAADVAERRDSYTAIATTQDWHIDPGRHFSKNPNYVDTWPVHCVAGTPGAALHPQIADLGVDGHFAKGRYSDGYSGFEARLLNPAADLEDESGPLLEDWLKQRQVTAVDVVGIATDHCVRATALDAAKAGFATTVITPLTAAVSPENLPSLYSELRESGVTVLTLG
>NZ_CP034412|1198514:1206648|1203889_1205188_-|WP_138173088.1|DBSCAN-SWA
MLTSLFTDHYELTMLQASLASGAAHRPSVFEAFARRLPDGRRYGVVAGTGRLLEGLANFRFEDEQLKFLSDNKVVNKETLDYLENFKFTGNITGYAEGELYFPNSPLLTVESTFAEACVIETFVLSTLNHDSAIASAASRMIAAAGERPCIEMGSRRTHEEAAVAAARAAAIAGFDSTSNLEAGARYDIPTVGTSAHSFTLLHESEREAFQAQVDALGVDTTLLVDTYDVEQGVRTAVEVAGAELGAVRLDSGDLVQQATWVRELLDDLGNWNTKITVTSDLDEYAIAALASAPVDSYGVGTALVTGSGHPTASMVYKLVARQDTSGEWIPVAKAATNKASTGGRKSGVRQLNERNRAVNEIVVLGEHTTEGPERLLTVPLVTHGEIDEKYVSASGVQLARQRHHASIQEMPGIARKLQRGEPVIPTILVNE
>NZ_CP034412|1198514:1206648|1199254_1200817_+|WP_138925970.1|DBSCAN-SWA
MVAHILKLKLTLLRNGFRRSTWQLVGVIIGTLYALGVVAMLILAAWFSADLQWLSYISILASSLVVIGWAIVPPLLTGVDLTLEPQRFVHFGIEPKTLGRALVLAGFVSIPALITVLAMAGFSVLWRLDPGVLLLALVANLGTAVLAVFGCQYLTIQATALRSKRRFREATFLIFFLLLVSLGPIIGMLTEAATSALDWIDPVATVLAYTPFGTLGAVAPAAAEGAWLAAIGHLLYGLVCLAVLYWLLLRATANAVVTAPAPQRAASAKGLGPFKWMPPTPWGAVAARALVYWLKDPRYAIGVLMVPVLPVIFYFAGSQSGSYAMMFLLGPIFGILMGFSISADVSYDNTAFSLHVLTGVRGRDDRIGRMLACLLVGLVPVLLGAILPGALTNQYWRIPADVGLSLGALLVALAISSVVSARYTYAVPLPGENPMKTPPGNGVRVALTQLLTFGGMGLLLLPLVIPYLFAIFGRIQPLGWVTLAGAFVYGGILLLIGVRVGGKWMDARLPELMQAVLLNK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_138173052.1|1198514_1199279_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.6e-14	24.0
WP_138925970.1|1199254_1200817_+	transporter	NA	NA	NA	NA
WP_054821750.1|1201078_1201333_+	DUF3039 domain-containing protein	A0A2R4A1S7	Microbacterium_phage	3.0e-12	44.3
WP_138925971.1|1201407_1203174_+	DEAD/DEAH box helicase family protein	I4AZM6	Saccharomonospora_phage	2.8e-88	36.7
WP_138925972.1|1203287_1203881_-	isochorismatase family protein	A0A1V0SL12	Klosneuvirus	4.5e-06	25.0
WP_138173088.1|1203889_1205188_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.0e-52	38.5
WP_138925973.1|1205499_1206648_+	diguanylate cyclase	A0A1B0Z064	Pseudomonas_phage	7.1e-08	35.1