CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040872	Agromyces sp. HY052 chromosome, complete genome	4 crisprs	csa3,WYL,DinG,cas3,DEDDh,Cas9_archaeal	0	2	0	0

Cas Category Instructions

Results visualization

1. NZ_CP040872

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040872_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040872_1

81749-81849

Orphan

Consensus_repeat	Method
CGTCAGCCTCTACGACCGGCCCTCAACCGATTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040872_1

>merge|NZ_CP040872|1|81749-81849|CRISPRCasFinder
CGTCAGCCTCTACGACCGGCCCTCAACCGATTCCAGACGGCAACAGACGAGGCACAACACCCAGCACCGTCAGCCTCTACGACCGGCCCTCAACCGATTCC

>NZ_CP040872|1|1|81749-81849|CRISPRCasFinder
CGTCAGCCTCTACGACCGGCCCTCAACCGATTCC	AGACGGCAACAGACGAGGCACAACACCCAGCAC
CGTCAGCCTCTACGACCGGCCCTCAACCGATTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040872.1\|WP_139418213.1\|78939_79380_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NZ_CP040872.1\|WP_139415413.1\|89799_90756_+\|Ku-protein	unknown	unknown	gnl\|CDD\|238408
NZ_CP040872.1\|WP_139415412.1\|87231_89715_-\|ATP-dependent-DNA-ligase	unknown	unknown	gnl\|CDD\|236599
NZ_CP040872.1\|WP_139415401.1\|76880_77732_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
NZ_CP040872.1\|WP_139415399.1\|75236_76361_+\|23S-rRNA-(uracil(747)-C(5))-methyltransferase-RlmC	unknown	unknown	gnl\|CDD\|235128
NZ_CP040872.1\|WP_168197042.1\|74624_75203_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|377233
NZ_CP040872.1\|WP_139415405.1\|81912_82356_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP040872.1\|WP_139415410.1\|85934_86201_+\|Rho-termination-factor	unknown	unknown	gnl\|CDD\|237171
NZ_CP040872.1\|WP_139415409.1\|85081_85312_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139415402.1\|77811_78774_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP040872.1\|WP_139415404.1\|80584_81439_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|294013
NZ_CP040872.1\|WP_139415403.1\|79452_80088_+\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653
NZ_CP040872.1\|WP_168197029.1\|74044_74440_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139415414.1\|90837_91278_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380530
NZ_CP040872.1\|WP_139415406.1\|82701_82995_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642
NZ_CP040872.1\|WP_139415400.1\|76463_76715_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139415411.1\|86213_87191_+\|DNA-topoisomerase-IB	unknown	unknown	gnl\|CDD\|226099
NZ_CP040872.1\|WP_139415396.1\|73345_74014_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP040872.1\|WP_139415407.1\|82957_84334_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_168197043.1\|84602_84983_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|377256

Protein	Function_ID	Function_description	E-value
NZ_CP040872.1\|WP_139418213.1\|78939_79380_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	1.67352e-55
NZ_CP040872.1\|WP_139415413.1\|89799_90756_+\|Ku-protein	gnl\|CDD\|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	6.49325e-120
NZ_CP040872.1\|WP_139415401.1\|76880_77732_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	3.16189e-83
NZ_CP040872.1\|WP_139415399.1\|75236_76361_+\|23S-rRNA-(uracil(747)-C(5))-methyltransferase-RlmC	gnl\|CDD\|235128	PRK03522, rumB, 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC.	0
NZ_CP040872.1\|WP_168197042.1\|74624_75203_-\|DUF402-domain-containing-protein	gnl\|CDD\|377233	pfam04167, DUF402, Protein of unknown function (DUF402). Family member FomD is a predicted protein from a fosfomycin biosynthesis gene cluster in Streptomyces wedmorensis. Its function is unknown.	3.89006e-10
NZ_CP040872.1\|WP_139415405.1\|81912_82356_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.5612e-13
NZ_CP040872.1\|WP_139415410.1\|85934_86201_+\|Rho-termination-factor	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	3.57619e-05
NZ_CP040872.1\|WP_139415412.1\|87231_89715_-\|ATP-dependent-DNA-ligase	gnl\|CDD\|236599	PRK09632, PRK09632, ATP-dependent DNA ligase; Reviewed.	0
NZ_CP040872.1\|WP_139415402.1\|77811_78774_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.70385e-45
NZ_CP040872.1\|WP_139415404.1\|80584_81439_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|294013	cd00383, trans_reg_C, DNA-binding effector domain of two-component system response regulators. Bacteria and some eukaryotes use two-component signal transduction systems to detect and respond to changes in the environment. The systems consists of a sensor histidine kinase and a response regulator. The former autophosphorylates a histidine residue on detecting an external stimulus. The phosphate is then transferred to an invariant aspartate residue in a highly conserved receiver domain of the response regulator. Phosphorylation activates a variable effector domain of the response regulator, which triggers the cellular response. This C-terminal effector domain belongs to the winged helix-turn-helix family of transcriptional regulators and contains DNA and RNA polymerase binding sites. Several dimers or monomers bind head to tail to small tandem repeats upstream of the genes. The RNA polymerase binding sites interact with the alpha or sigma subunit of RNA polymerase.	4.40702e-29
NZ_CP040872.1\|WP_139415403.1\|79452_80088_+\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	1.10944e-119
NZ_CP040872.1\|WP_168197043.1\|84602_84983_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|377256	pfam04237, YjbR, YjbR. YjbR has a CyaY-like fold.	2.93947e-16
NZ_CP040872.1\|WP_139415414.1\|90837_91278_-\|hypothetical-protein	gnl\|CDD\|380530	cd06307, PBP1_sugar_binding, periplasmic sugar-binding domain of uncharacterized transport systems. Periplasmic sugar-binding domain of uncharacterized transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes.	0.00442772
NZ_CP040872.1\|WP_139415406.1\|82701_82995_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	5.78571e-26
NZ_CP040872.1\|WP_139415411.1\|86213_87191_+\|DNA-topoisomerase-IB	gnl\|CDD\|226099	COG3569, COG3569, Topoisomerase IB [DNA replication, recombination, and repair].	2.43778e-60
NZ_CP040872.1\|WP_139415396.1\|73345_74014_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	3.55981e-37

>NZ_CP040872.1|WP_139415404.1|80584_81439_+|winged-helix-turn-helix-transcriptional-regulator
MSLAFAPAPARTASVRTAPDRTAPARTVQARTAPSLSAPLASPAAPLRSVPASVTELDGAVRSVAAEAAPAAAPAAPRVRAVPEGTEARGFVLYVGIDEAKALADGTSLHRIVEALRALTSEVSPSAETYAAVALAPEGAGGRDVDVVRLALQDPSALAKQREGHGVRDDADRHPNGVIIDISRKRVLLDGEAAGLTYKEFELLQYLVLREGRTIDRHELIENLWDADDEAPSERTIDVHVRRLRSKLAHYQDIVRTVRGVGYRFDRHADVSIRQASTPSPDLY
>NZ_CP040872.1|WP_139415403.1|79452_80088_+|uracil-phosphoribosyltransferase
MRVHVADHPLITHKLTVLRNVNTPSPVFRSLVEELMTLLAYEGTRGVRVEPVEIMTPVAPTTGVRIADPRPLIVPILRAGLGMLEGMTKLVPTAEVGFLGMARNEETLEPTTYAERLPDDLSDRQCFVLDPMLATGGSLIAAVEFLLKRGATDVTAICILAAPEGLAAVEKALEGRGEVSIVLGAVDERLNEVGYIVPGLGDAGDRLYGTV
>NZ_CP040872.1|WP_139418213.1|78939_79380_-|nucleoside-deaminase
MRLALAEAAQAPATRDVPVGAIVVDDSGEVIAARRNERELLGDPTAHAELLALRTAAEVTGDWRLTGSTLVVTLEPCVMCAGAILAARIPTVVFGAWDERAGAAGSLYDVLRDRRLNHRVEVFAGVEADAAAKLLLDFFEDPLRRP
>NZ_CP040872.1|WP_139415402.1|77811_78774_+|cation-diffusion-facilitator-family-transporter
MSASGGTKAIIAAFLANTGIALTKFIAWFFSGSASMLAEAVHSVADAGNQLLLILGGRQAKKKADKEHPFGYGRERYVYAFVVSIILFSVGGIFSIYEGVDKLTHPHELENAWLPLLVLTIAIVLESFSLRTAVKESNLVRGRQSWVQFVRRAKAPELPVVLLEDIAALIGLVFAFIAVGLTVITGNPLFDAIGTLMIGTLLVLVAIVLGIETKSLLVGEGANDDDLARIEQAILAGPEVERIIHMKTLYLGPDELLVGAKLGFAADARLLEVAAATNAIEHRIRDAAPSARVIYIEPDVYVEPNHPAPPTDAIVIKGLE
>NZ_CP040872.1|WP_139415401.1|76880_77732_-|pyrroline-5-carboxylate-reductase
MSAEATVRLPAIAFLGAGSMARAILTGLLQPGIEVDGGIRATNRGAEKAAELAELPGVAAFATESDAAANRTAVAGAKIVVVAVKPAMVPALLEEIADALVPGTIVVSVAAGVTVATFESLLPASVAVIRAMPNTPAVVGRAVTGISAGTRASDADLALAVALFETVGEVLVVPEDQIDALSTISGSGPAYVFYLIEQLTATAVGKGFTPEQAAVMVEGTFRGASELLAASDDGPGELRRRVTSPNGTTERAVALLESASLKQIFDRATDAALARARELAAGA
>NZ_CP040872.1|WP_139415400.1|76463_76715_+|hypothetical-protein
MRRITPFFATMIVASWLFVIGFAVGFEGELAADPALTREHPDALFAGLAMGLGAVGAALVIVAGVRLTTALVRTRSDKAHAAH
>NZ_CP040872.1|WP_139415399.1|75236_76361_+|23S-rRNA-(uracil(747)-C(5))-methyltransferase-RlmC
MDCSYFDAGRCTSCSLMGQPYERQLADKQRHAEELLAAHDGLDWLPPVGSSEAGYRNKAKMVIGGTVDAPTIGILDADGHGIDLEACGICSPGHRAAFPVISAFITRAGLIPYDVPSRRGELKHLIITESPDGELMVRFVVRSTEPVSRIRKHLPWLLAALPDARVVTANVLPEHKAVLEGAHEIVFTEASTLPMRLGDVTMHLRPQSFFQTNTEIAEALYVEARDWVRALAPDSAWDLYSGVGGFALHIADAAASVTGIETSVEAVASAELSRTDAALSRVRFEAGDATAFASGAGAAPDLVIVNPPRRGIGRELSGWLEASAVRHVLYSSCNAASLARDLEAMPSLRPVRGRVFDMFPQTTHFEVMVLLERV
>NZ_CP040872.1|WP_168197042.1|74624_75203_-|DUF402-domain-containing-protein
MSSPDDRPSVPGDLVRVRAMKWPEQPHWEFDGRWLGSDEHGDWIGFPAGTRFDRPGHGFIATWDSVTLFPREGWAATFCTGHPRGVGIYVDIATVSEWRADASVPTLSYVDLDLDVVERAGAPAFIEDEDEFAEHAVEFGYPPEVVARARADADAVLRAVQRRDAPFDGATSAAWLERDGLGAQGSSGNRGV
>NZ_CP040872.1|WP_168197029.1|74044_74440_-|hypothetical-protein
MNAADTVSVIAEVIGWFALAAGLVLLGLALLIRLADGRWLRTEAVVIDEDGGSVVRWFTDDGFQSRRLSEDERAHVTRPDEEPAYYKEREPYRLRLHEPPPGRRVIRILGIVFIGIAAASAAVGLVLMFAG
>NZ_CP040872.1|WP_139415396.1|73345_74014_+|TrkA-family-potassium-uptake-protein
MVDRIRHDAPVLVIGLGRFGAATAGQLDRLGREVLAVDESEALVQKWSDRVTHAVVADARSIDALKQIGAQDFSIAVCAVGSSIEASVLITANLVDLKIPQIWTKAISASHGKILQRIGASHVIYPEREAGERTAHLVSGRMLDFIEFDDDFALVKMYPPKPIRGKNLTESGVRSKHRVTVVGVKSPGKPFTYATENTVVSNHDLIIVSGTEGDIEKFAALE
>NZ_CP040872.1|WP_139415405.1|81912_82356_+|MarR-family-transcriptional-regulator
MADRAITVAAWESLFRAQVTIMRALAAEFPSDVISLNEYDVLFNIARAPQRRLRLKELNQHVLITQPSVSRLVDRLTARGLIEKLPDLNDGRGTIVAITDEGFALFRRIAIIHMEAINRQFGDTLSEDELHTLAELCNRLRLELERV
>NZ_CP040872.1|WP_139415406.1|82701_82995_-|GNAT-family-N-acetyltransferase
MATDIVEIVRNDDRHRYELSFGGEPAGFAQYRLRDGAIVFHHTVVLPEFEGRGLGSKLARFVLDDAVARGERIVPECPFIAAYLRRHEGYEASVDWP
>NZ_CP040872.1|WP_139415407.1|82957_84334_-|hypothetical-protein
MRRAFAGGGPVSFNRGLVAPPGAVVRAAARLGSLRLPPLAAHLRRLFALLIAVGVSIVLYRALDPRFSPVSGQHGIDVFWMVPALAGGAAVGACLVVTSASSRGIAGLAKLGLPGVPVESRAIANGLTWAAIAMLAVHFTSSAFDVLPGGHHAAGTMLGVGFGVGAFRLHHHAIEHEAYRTFNLVAMLLAVGSLASMSITPTGEWWTRNFSTLGTSNDLAAVCFNVALIVSGLGMAVLSSLLTRGLAHGPFALRHGARTVMRLLVVFVGVGLAGVGFVPIDTDTELHNAFALAVAAAFAALCLGVRFFAPGIPRAFARFSYLSLAVEAMAMVAYDRLGLFSLTVFEIVAFTLVFAWLIALVVATVDGHGDTRADAAAHPRRIRRPLPALAPSRRRFADRWLCSGRRRYRAVLVARAATAAAPRGAARRRRLRRSRGASRGGPVESRHGYRHRRNRPQR
>NZ_CP040872.1|WP_168197043.1|84602_84983_-|MmcQ/YjbR-family-DNA-binding-protein
MDPQHPLVERVRAVCLALPEAVEVEAWGRPTFRAAKPIFVHVSASMERPLSIVVKTDPDEHLALVQDARFFGPPYYDRDHWVGVDLDQPDTDWALLAELIETSYRQVANRRQLTALDALRPAHAED
>NZ_CP040872.1|WP_139415409.1|85081_85312_-|hypothetical-protein
MNDDGRGDRAGGPTASVEHWWPRLSIGAKHRVLADMSAPIDAETAHEIEELCGEPAPVRLTPADEAFVRTQIESVD
>NZ_CP040872.1|WP_139415410.1|85934_86201_+|Rho-termination-factor
MPGRRNDSLKDPELYEELRDDGASKEKAARISNAAAKQGRSAIGRKGGQSGDYEDWTVDALRKRAKELGLSGYSGKRKADLISALRNH
>NZ_CP040872.1|WP_139415411.1|86213_87191_+|DNA-topoisomerase-IB
MPRLRRVEPYVSPGFARIARGRGFGYVHSSGGAAGRAERARITDLAIPPAWRDVWIADAPNAHILAVGVDAAGRRQYLYHPAWRERQDAEKFQRMTALAEALPTARRSVARDLALDGSPRELVLAAAFRTLDLGGIRIGSEESLAGFRSRGLTTLLVRNARLVDDETVRFRFRAKGGVTQKLCVTDAALAAFIGRAGERSPASRLYAWPAGRSTRAAAPVDVNDDIRDRTGGDFTAKDFRTLRGTIAAADHLAGAGPSSTERARKATVRGAIEAAAAALGNTPAIARGSYVDPRVLAAYEEGVVVASGADRERRLIELLGRVDES
>NZ_CP040872.1|WP_139415412.1|87231_89715_-|ATP-dependent-DNA-ligase
MADGTRQLVEVDGRRLRLTNLDKVMYPETGMTKGEVISYYAEIAAAMVPLVAGRPVTRKRWVHGVGTADAPEQPFFEKNLADHAPEWVRRGIQHHSDGDKAYPIAGDRATLVWLAQQAALELHVPQWRFDAAGEPANPDRMVFDLDPGDGMGLAECAEVARLVRDLIAGMGLEAVPVTSGSKGIHLYAALDGSQSSDQVSAVAHELARALEADHPELVVSSMRKTLRTGRVLIDWSQNNGKKTTIAPYSLRGRPRPTVAAPRTWEELDDAGLRQLEASEVLERVAASDDPMRAITERSHGGPLTQYLSMRSATATPEPMPESAWGEASPGEPRFVIQEHRARRLHFDLRLERDGVLKSWAVPKGVPESSGTNHLAVQTEDHPMEYAAFEGTIPKGEYGAGAMTIWDAGTYAAEKWRDDEIIIDIDGRPGGPLGGQVRLALIRTDGQGEKSSWLLHRMKDQTVRHEEPPQAAAAQAAAPVPAAAPVPRADGVVGQITQRPMLATASTLGMLAGEDWAIEWKWDGIRVLARVEAGGVRLLSRNGVDITARYPELAALPAVVRGEALLDGEIVALDADGRPDFGRLQHRMNLTKPREVERVAASVPVRLLLFDVLEVDGRPVVDEPYRERRARLAGLVRVRRGVPVEVPAPTSGSPAEALEESRRLGLEGLVAKRPDSRYRPGARSNDWLKLKLTRTQEVVIGGYRRGIGTRTGRIRSLLVGIPSDADRERAGSGRTSTEGLRLEYAGRVGSGLGERELERLLTTLRPLEQPESPFVQVPAADMNDAVWVRPALVGEIELGDWTSTGVARHPRWRGLRPDESPADVVRET
>NZ_CP040872.1|WP_139415413.1|89799_90756_+|Ku-protein
MRAVWKGAVTFGLVNVPVKLYSATEDHDVSLHQVHDEDGGRIRYQRKCEVCGKVVDYKNIDKAYDDGEQTVVITDADLKALPAERSREIEVVEFVPSEQLDPIMFDRSYYLEPDSASSKAYVLLRETLESTDRTAIVQMALRQKTRLAALRVHGDVLMVQTLLWSDEVRAAEFASLDEPVKISAKELDLSKQLVESLVSDFDPEQYVDEYQQELRTLISAKLEQGEGIDTAATFGEEPEEEAGGEVIDLMEALRQSVAAKREAGGATGTSSGAGSKGTSSKGTSSKGTSSKGTKKKSTSKSSDSPKKAAGTRKRAASE
>NZ_CP040872.1|WP_139415414.1|90837_91278_-|hypothetical-protein
MRRIITSTALVFAGALLLSGCATSGGTEASPSADSCEVVRVEARDISNGAQNAILAVSDPAELASSLDALSERVDALGEEAADDSAVADALDALDEKIDAASDWAETVPTEAEVEAGAEVDADAQTAQAEGIQAAAIKVTEVCAAE

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Crispr_ID: NZ_CP040872_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040872_2

2426965-2427053

Orphan

Consensus_repeat	Method
GCATGTTCTAGACCACCATTCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040872_2

>merge|NZ_CP040872|2|2426965-2427053|CRISPRCasFinder
GCATGTTCTAGACCACCATTCCGGATGACAGGGAGGGATTCGAGCCGCAGTGGGCTGCGCACGTGGCCATGTTCTAGACCACCATTCCG

>NZ_CP040872|2|2|2426965-2427053|CRISPRCasFinder
GCATGTTCTAGACCACCATTCCG	GATGACAGGGAGGGATTCGAGCCGCAGTGGGCTGCGCACGTGG
CCATGTTCTAGACCACCATTCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040872.1\|WP_139417393.1\|2433123_2433744_-\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NZ_CP040872.1\|WP_139417383.1\|2422978_2424022_-\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NZ_CP040872.1\|WP_139417379.1\|2418761_2419691_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|234835
NZ_CP040872.1\|WP_139417395.1\|2434370_2435147_-\|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl\|CDD\|223344
NZ_CP040872.1\|WP_139417381.1\|2420904_2421822_-\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|234869
NZ_CP040872.1\|WP_139417389.1\|2430706_2431495_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP040872.1\|WP_139417390.1\|2431551_2432364_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NZ_CP040872.1\|WP_139417374.1\|2413700_2413907_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417380.1\|2419687_2420908_-\|acetylornithine-transaminase	unknown	unknown	gnl\|CDD\|235112
NZ_CP040872.1\|WP_139417377.1\|2416672_2417290_-\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|234840
NZ_CP040872.1\|WP_139417382.1\|2421824_2422982_-\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl\|CDD\|235441
NZ_CP040872.1\|WP_139417378.1\|2417286_2418762_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CP040872.1\|WP_139417387.1\|2429053_2429701_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP040872.1\|WP_139417391.1\|2432455_2432842_-\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
NZ_CP040872.1\|WP_139417375.1\|2414043_2415348_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NZ_CP040872.1\|WP_139417386.1\|2428130_2429057_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP040872.1\|WP_139417376.1\|2415454_2416060_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|339675
NZ_CP040872.1\|WP_139417394.1\|2434007_2434358_+\|DUF1844-domain-containing-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417388.1\|2429771_2430638_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270408
NZ_CP040872.1\|WP_139417392.1\|2432873_2433068_-\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676

Protein	Function_ID	Function_description	E-value
NZ_CP040872.1\|WP_139417393.1\|2433123_2433744_-\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	2.33268e-88
NZ_CP040872.1\|WP_139417383.1\|2422978_2424022_-\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	1.79019e-148
NZ_CP040872.1\|WP_139417395.1\|2434370_2435147_-\|Fpg/Nei-family-DNA-glycosylase	gnl\|CDD\|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	6.39408e-62
NZ_CP040872.1\|WP_139417381.1\|2420904_2421822_-\|acetylglutamate-kinase	gnl\|CDD\|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	8.9563e-145
NZ_CP040872.1\|WP_139417382.1\|2421824_2422982_-\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl\|CDD\|235441	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ.	3.34823e-177
NZ_CP040872.1\|WP_139417390.1\|2431551_2432364_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.54683e-67
NZ_CP040872.1\|WP_139417379.1\|2418761_2419691_-\|ornithine-carbamoyltransferase	gnl\|CDD\|234835	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional.	0
NZ_CP040872.1\|WP_139417380.1\|2419687_2420908_-\|acetylornithine-transaminase	gnl\|CDD\|235112	PRK03244, argD, acetylornithine transaminase.	0
NZ_CP040872.1\|WP_139417377.1\|2416672_2417290_-\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|234840	PRK00802, PRK00802, DNA-3-methyladenine glycosylase.	1.87963e-68
NZ_CP040872.1\|WP_139417387.1\|2429053_2429701_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.23792e-54
NZ_CP040872.1\|WP_139417378.1\|2417286_2418762_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP040872.1\|WP_139417391.1\|2432455_2432842_-\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	4.4608e-62
NZ_CP040872.1\|WP_139417375.1\|2414043_2415348_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NZ_CP040872.1\|WP_139417386.1\|2428130_2429057_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.65946e-49
NZ_CP040872.1\|WP_139417376.1\|2415454_2416060_+\|DNA-binding-protein	gnl\|CDD\|339675	pfam16264, SatD, SatD family (SatD). This family consists of uncharacterized proteins around 220 residues in length and is mainly found in various Streptococcus species. The function of this family is involved in acid resistance.	0.00907753
NZ_CP040872.1\|WP_139417389.1\|2430706_2431495_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.13351e-150
NZ_CP040872.1\|WP_139417388.1\|2429771_2430638_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.79265e-93
NZ_CP040872.1\|WP_139417392.1\|2432873_2433068_-\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	6.18843e-19

>NZ_CP040872.1|WP_139417383.1|2422978_2424022_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MTFTVAVSGASGYAGGEILRLLADHPDFDVRTVTAHSNAGQPLIAVQPHLRSYTHLTLKDTTAENLAGHDIVFLALPHGASGAIAEQLPPETLVIDCGADHRLESETDWAAFYGGEFHGAWTYGVPELPRLSGTQRDRLAKTKRIAAPGCNASTVALSLAPGIRAGVIEAADVVAVLAVGPSGAGKSLKAHLLGSELLGSANPYSVGGVHRHIPEIQQALRWAGGGNPTISFTPVIVPMSRGILATSTARIVPGTDAAAVRTAWEDAYAGERFVQLLPAGQFPRTADVLGANTALLGLQIDEKAGRVVVVAAVDNLVKGTAGAAIQSANIALGLTESTGLPVNGVAP
>NZ_CP040872.1|WP_139417382.1|2421824_2422982_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MTITHPQGFEAAGIAAGIKRTGALDLALVVNRGPAQQAAAVFTSNRAQANPIIWSRQVAADGIVSAIVLNSGGANCFTGPEGFQVTHRTAEAAASGLGVAAGDVLVCSTGLIGDQLDGEVLEEGVVSAIARLSSEDGGGDDAARAIMTTDTTPKQVVVVGDGWSIGGMAKGAGMLAPGLATMLVVVTTDAALSAADLDSALRAATRVTFDRLDSDGCMSTNDQVTLLASGASGVAPEPTEFAAALTEACRSLAMQLQADAEGASHDIAIEVVGAVTEDDAVEVGRSVARNNLFKAAIFGNDPNWGRVLAAIGTTSAPFDPYLVDVSMNGVRVCHAGRPDAPRDDVDLTPRATHVLIELHAGEASATIFTNDLTHDYVHENSAYAS
>NZ_CP040872.1|WP_139417381.1|2420904_2421822_-|acetylglutamate-kinase
MSDDTEPDETGSDDTNDAAAKAQVLIDSLPWLKRFHGETIVVKFGGNAMVSPELQRAFAEDMVYFRYAGIKPVVVHGGGPQISTMLERLGIPSEFRGGYRVTTPETMDVVRMVLSGQVNRELVSLINEHGPLASGLSGEDAGLFTGRRRGAVVDGEEVDLGLVGDVVAVDPAAVLAELDAGRIPVVSSIAPDGDVTGQSLNVNADSAAAALAVALGAAKLVILTDVAGLYRDWPNRDSLVSVIDVPSLIDLLPNLESGMIPKMAACLEAVEGGVSKAAIIDGRVPHSILLEVFTQSGIGTEVVAA
>NZ_CP040872.1|WP_139417380.1|2419687_2420908_-|acetylornithine-transaminase
MIDWQQRFDQRIMRSIGMPLAKLEHGSGVWVTDAAGTTYLDFLAGIAVNSLGYAHPVFVEAVTTQASKLAHVSNYFTTEPALELAERLVRLAGAGAEGRAWFGNSGAEANEAAFKLARLNNSGGARTRVIALVDAFHGRTMGSLALTGKPHMRTPFEPLAGGVEHIPATIEALEASIDDAVAAVFIEPIQGEAGVRELPEGFLEAARELTLRHGALLIVDEIQTGAGRTGEWFGFQHAGITPDAITVAKGIGGGIPIGGLITFGHASELYQKGQHGSTFGGNPLATAVSNAVLGEIERAGLVANAAVRGPQLRRRIEAIGSPLVAGTRGRGLLVGVALSAPVAGDVVVHAMRHGLIVNAANDTTIRIAPPLIIGDAEIDEFESRFARALADAHPYPTDLSTNGRTA
>NZ_CP040872.1|WP_139417379.1|2418761_2419691_-|ornithine-carbamoyltransferase
MTRHFLRDDDLSQAEQSEILDLAEQLKADRWSRTPLAGPQTVAVIFDKSSTRTRVSFAVGIADLGGSPLIISTANSQLGGKETPSDTARVLERMVSAIVWRTYAQAGLEQMAAGTTVPVVNALSDDFHPCQLLADLLTIREHKGRLAGLTVTFLGDGRSNMAQSYLLAGATAGMHVRIAAPAEFAPESSVVADAERIAATTGGSVAVVTDARESVSGADVVVTDTWVSMGKEEEKAHRVATFGSYQVDAELMSLAESDAVFMHCLPADRGYEVSADVIDGPRSIIWDEAENRLHAQKALLVWLLERKGA
>NZ_CP040872.1|WP_139417378.1|2417286_2418762_-|argininosuccinate-lyase
MSDVTEAGGAAEAHGTNEGSLWGARFASGPAPELARLSKSTHFDWQLAGYDLAGSRAHARALAAAGYLEADELDAMLAGLDTLEARVVSGEIVAGETDEDVHGALEAALIAIVGAELGGKLRAGRSRNDQIATLVRLYLKDHAAIIGRDLVHLIDALAAQADAHRTAIMPGRTHLQHAQPVLLAHHLLAHAWALSRDLERLVDWTKRADVSPYGGGALAGSTLGLDAASVARDLGLGGPAENSIDGTSSRDVVAEFAFVTAMIGIDLSRIAEEIILWNTREFDFVTLHDGYSTGSSIMPQKKNPDIAELARGKSGRLIGNLTGLLATLKALPLAYNRDLQEDKEPVFDSVETLEVLLPAFTGMVATLTFHTERMTQLAPAGFSLATDVAEWLVKQRVPFRDAHEITGALVRHAEEHGLELDDVDDAALAAISPHLTPEVREVLTVEGSVASRDGIGGTAPGRVAEQFSRLADRVRHLVAGLPDARSPEARS
>NZ_CP040872.1|WP_139417377.1|2416672_2417290_-|DNA-3-methyladenine-glycosylase
MNSLITPNREFFLQDPVVLAPLLLGSVLSYDAPDGRVAIRLSELEAYRGVGEDPGSHAFRGRTPRNEVMFGDPAHLYAYFSYGMHVCLNIVARAAGSSSGMLMRGATVVDGIEVARRRRPGVSDRDLARGPGRLSKALGVPLGARGSDLLALPFTLQVPATPLHSASGPRTGVGGEGGGSQYPWRFWLPGDEGVSPYRRHKLAAE
>NZ_CP040872.1|WP_139417376.1|2415454_2416060_+|DNA-binding-protein
MFVVTADQVSSRTQADLAGAERDRIQREHGETLLLPVARNAGDEVQLLTSDALTVVEVVFELTRDGAWSIGIGCGTVRAPLPADIREASGEAFFAARDAVERAKKSAPRLAIEAAHDDAVHVEALFRLALLLRERRSDQGWEVYDRIIAGAMQSEIADELGVSAPAISSRMKSGNIRAELDAVPALARLLENLDSSTGARE
>NZ_CP040872.1|WP_139417375.1|2414043_2415348_-|tyrosine--tRNA-ligase
MVSDPVILATQQNDASFDDVWEELVWRGLVHVSTDQAALKELLAGEPITYYCGFDPTAPSLHLGNLVQLLTMRRIQLAGHRPLGLVGGSTGLIGDPRPTAERTLNTKETVVEWVGYLQGQVSRFLSGEGENAVRLVNNLDWTGGLSAIDFLREIGKHYRVGTMLKKDAVASRLNSDAGISYTEFSYQILQGFDYLELHRQYGCVLQTGGSDQWGNLTSGTDLIHRIEGASVHAIGTPLVTNADGTKFGKSEGNAIWLDDAMCSPYAFYQFWLNTDDADVISRLKIFTFLSRERIEQLEELVATEPFKREAQRVLATEVTTLVHGADATEAVTAASRALFGQGDLAALDPATLMAALRELPNTTATTDASIVQLLVDTGLVSSQSEARRAINQGGVSLDNVRIDDDTATLEGRVAAGGMAVLRRGKKTLAGVFVE
>NZ_CP040872.1|WP_139417374.1|2413700_2413907_+|hypothetical-protein
MPDPDRIELPEPSFSFGHPEEDGSERFKHEKAIPSRFGIVVPLEEDELGAINTGLIRSAALPLLWGNE
>NZ_CP040872.1|WP_139417386.1|2428130_2429057_-|ABC-transporter-permease-subunit
MSGSSVLFDAPGPKARRASLISSIVAGVLIVGGLAWMALTLAAPRESGGITLPGFFDPSRWDIFADPELWSFIVFEGVFGTLRAALIASVFAIILGIILSLLRSSAIAWIRIPTAVVLEFVRGMPVLLMMLFILLVLNTGAFWAVVAALTLYNGALIGEALRAGLAALPRGQREAGLSLGMRPLQSKMLVEFPQAFRQMLPIIVAQLVVLLKDTSLGYIVGYTELLRVNMNNLVNFYGNRYLFSFFVVTLVLYLAMNLSLSWFARWLSKRTSSSSSGKRLDPEDPNQAVLVAEASASARQSESHEPRT
>NZ_CP040872.1|WP_139417387.1|2429053_2429701_-|ABC-transporter-permease-subunit
MDAVIDNLPTYFEGFRMTLLLLVVSGISALVLGTIVAAMRISPVPSLRAFATVYTELVRNTPLTLVLFFCAIVLPYLGPDLAYAASAMVGLSVYTSPFVAEALRSGINGVPVGQAEAARSVGLGFGQTVSLIVLPQAFRMTIPPLINVFIALTKNTSVAGGFFVFELFGATSRLANANGDAVIAILLGAATLYLVITIPLGVIAAQLERKWVVQR
>NZ_CP040872.1|WP_139417388.1|2429771_2430638_-|transporter-substrate-binding-domain-containing-protein
MKRMRIALVAAAAASALALAGCAGGDTGGTEEPSAEPAPTFEAGTTMAELADAGTITVGTKFDQPLFGLMGPSGVPEGFDVEIAKIIASELGISEDKIEWTETVSANREPFIENGQVDIVVATYTINDKRKEVVSFAGPYYMAGQSILVLADNDDIKSEEDLVGQPVCSVTGSTSAANLQELGAELVATDTYSNCLEPLRRGEVVAVSTDNVILAGLVTQNEGEFKVVGEPFTEEPYGIGLALEDTEFRNWINDVLEESYEDGRYEEAWDATAGTVLPFVDPPAPDRY
>NZ_CP040872.1|WP_139417389.1|2430706_2431495_-|ATP-binding-cassette-domain-containing-protein
MEPTQPAPPTSNISVRRGEPLVVIDHVEKHFGELHVLNDINTVVNRGEVVVVIGPSGSGKSTLCRAINRLETIDSGSIAIDGQELPAEGAALAKLRADVGMVFQSFNLFAHKTVLENVTLAPIRVKKMSRKDADAKAMELLERVGVANQAKKMPAQLSGGQQQRVAIARSLAMNPKLILLDEPTSALDPEMINEVLDVMIGLAKDGMTMIVVTHEMGFARKAADRVLFMADGKIVEEATPAVFFDHPETDRAKDFLSKILEH
>NZ_CP040872.1|WP_139417390.1|2431551_2432364_-|RNA-methyltransferase
MLENPRSPRVRAVAKLARKAARVESGLFLLEGPQAVAEALTFRPELVVELFATPSALERHGEIAEAAASADVDIEYVTEEVLDSMADTVTPQGFVAICRQFPTAVKDVFASKPKLVAILEEVRDPGNAGTIVRAADAAGADAVIFTGRTVDLYNPKVVRSSTGSIFHLPVAMGAELEDVLVRVRAAGLTVLAADVKGDDLLVARNDGVLAGPTAWVFGNEARGLPEEQLALAHRVVRVPIYGHAESMNLATAASVCLYESAFAQRSSHHG
>NZ_CP040872.1|WP_139417391.1|2432455_2432842_-|50S-ribosomal-protein-L20
MARVKRAVNAHKKRRVILERAEGYRGQRSRLYRKAKEQVTHSLVYAYRDRRQKKGDFRRLWIQRINAASRANGLTYNRLIQGLGLAGIEVDRRILADLAVNEPATFAAIVESAKKALPADTSAPKNAA
>NZ_CP040872.1|WP_139417392.1|2432873_2433068_-|50S-ribosomal-protein-L35
MPKQKTHSGSKKRFKITGSGKVKKQQAGMRHNLEVKSSKRKARLNQDKVVSAPDAKVIKKLLGR
>NZ_CP040872.1|WP_139417393.1|2433123_2433744_-|translation-initiation-factor-IF-3
MSDPRTNDRIRVPEVRLVGPAGEQVGVVKIEVALRLAQEADLDLVEVAPNSKPPVAKIMDYGKFKYEAAQKAKEARRNQANTILKEVRFRLKIDKHDYETKMKRAIGFLKAGDKVKAMILFRGREQSRPEMGVRLLQRFAEDVVEYGTVEHNPTIDGRNMVMVIGPLKNKSEAKAEANAQRAAAKARPAADAPGDGDAQTAEPSKG
>NZ_CP040872.1|WP_139417394.1|2434007_2434358_+|DUF1844-domain-containing-protein
MNSSSDETTVEGATRDIAEVPAVEIITTAAVHLMSAAAVKVGLAEDPEEQIDLDEARKLINALAGLITAGAPEISDMHARSLRDGLRSLQLAFREASVVPDPIGKGPGEKWTGPVN
>NZ_CP040872.1|WP_139417395.1|2434370_2435147_-|Fpg/Nei-family-DNA-glycosylase
MPEGDTVFQAARVLEAALAGHTITRTDFRVPALAEVDLAGLPVHSVGSRGKHVLLRIGDIVVHSHLKMEGEWRVFRPGEPWRRPAWQARAIVEVPEASAVGFDLGTLELFGAAEEAERLLYLGPDLLGADWDAAEAVRRLASVPETPIAVALAEQRNLAGLGNVYVNEVCFLRGILPTRPVGQVELDPVVALAVRVIRANRDRAVRTTTGDTRRGRRLWVHGRAGEACRRCGALIEHGRLGRTEIELRESWWCPNCQR

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Crispr_ID: NZ_CP040872_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040872_3

2566249-2566334

Orphan

Consensus_repeat	Method
CTCGAGAACGGGTTGTTGCCCGGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040872_3

>merge|NZ_CP040872|3|2566249-2566334|CRISPRCasFinder
CTCGAGAACGGGTTGTTGCCCGGGCGAGGCTGGGCCGGGCGCGAGCCCATGCCCTGCGAGCTCGAGAACGGGTTGTTGCCGGGGCG

>NZ_CP040872|3|3|2566249-2566334|CRISPRCasFinder
CTCGAGAACGGGTTGTTGCCCGGGCG	AGGCTGGGCCGGGCGCGAGCCCATGCCCTGCGAG
CTCGAGAACGGGTTGTTGCCGGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040872.1\|WP_139417501.1\|2560394_2561693_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP040872.1\|WP_139417496.1\|2555048_2556296_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380550
NZ_CP040872.1\|WP_139417507.1\|2567278_2568277_-\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|237061
NZ_CP040872.1\|WP_139417497.1\|2556364_2557234_+\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119324
NZ_CP040872.1\|WP_139418437.1\|2554257_2554950_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213191
NZ_CP040872.1\|WP_139418438.1\|2575370_2575991_-\|3-oxoacid-CoA-transferase-subunit-B	unknown	unknown	gnl\|CDD\|188219
NZ_CP040872.1\|WP_139417506.1\|2566936_2567200_-\|DUF448-domain-containing-protein	unknown	unknown	gnl\|CDD\|377288
NZ_CP040872.1\|WP_139417513.1\|2574308_2575358_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP040872.1\|WP_139417502.1\|2561966_2562569_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|180660
NZ_CP040872.1\|WP_139417508.1\|2570205_2570397_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367841
NZ_CP040872.1\|WP_139417510.1\|2571672_2572392_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417498.1\|2557230_2558259_+\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119323
NZ_CP040872.1\|WP_139417500.1\|2559339_2560302_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP040872.1\|WP_139417511.1\|2572953_2573688_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378615
NZ_CP040872.1\|WP_139417504.1\|2563509_2563986_-\|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl\|CDD\|234787
NZ_CP040872.1\|WP_139417514.1\|2576013_2576787_-\|3-oxoacid-CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
NZ_CP040872.1\|WP_139417509.1\|2570471_2571602_-\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|234737
NZ_CP040872.1\|WP_139417499.1\|2558294_2559290_+\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|235821
NZ_CP040872.1\|WP_139417512.1\|2573708_2574137_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417503.1\|2562618_2563509_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115

Protein	Function_ID	Function_description	E-value
NZ_CP040872.1\|WP_139417501.1\|2560394_2561693_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	0.00729606
NZ_CP040872.1\|WP_139417496.1\|2555048_2556296_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380550	cd06327, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs). Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.	3.00059e-142
NZ_CP040872.1\|WP_139417507.1\|2567278_2568277_-\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	5.06517e-170
NZ_CP040872.1\|WP_139417497.1\|2556364_2557234_+\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	4.36765e-61
NZ_CP040872.1\|WP_139418437.1\|2554257_2554950_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	2.50928e-99
NZ_CP040872.1\|WP_139418438.1\|2575370_2575991_-\|3-oxoacid-CoA-transferase-subunit-B	gnl\|CDD\|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	3.22727e-119
NZ_CP040872.1\|WP_139417506.1\|2566936_2567200_-\|DUF448-domain-containing-protein	gnl\|CDD\|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	6.28877e-21
NZ_CP040872.1\|WP_139417513.1\|2574308_2575358_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.86628e-20
NZ_CP040872.1\|WP_139417502.1\|2561966_2562569_-\|uridine-kinase	gnl\|CDD\|180660	PRK06696, PRK06696, uridine kinase; Validated.	4.72361e-41
NZ_CP040872.1\|WP_139417508.1\|2570205_2570397_-\|hypothetical-protein	gnl\|CDD\|367841	pfam04147, Nop14, Nop14-like family. Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.	0.00128232
NZ_CP040872.1\|WP_139417498.1\|2557230_2558259_+\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	5.42974e-84
NZ_CP040872.1\|WP_139417500.1\|2559339_2560302_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.66912e-25
NZ_CP040872.1\|WP_139417511.1\|2572953_2573688_-\|hypothetical-protein	gnl\|CDD\|378615	pfam11253, DUF3052, Protein of unknown function (DUF3052). This family of proteins with unknown function appears to be restricted to Actinobacteria.	0.00613848
NZ_CP040872.1\|WP_139417504.1\|2563509_2563986_-\|30S-ribosome-binding-factor-RbfA	gnl\|CDD\|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	3.15833e-46
NZ_CP040872.1\|WP_139417514.1\|2576013_2576787_-\|3-oxoacid-CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	4.64735e-98
NZ_CP040872.1\|WP_139417509.1\|2570471_2571602_-\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl\|CDD\|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NZ_CP040872.1\|WP_139417499.1\|2558294_2559290_+\|2-dehydropantoate-2-reductase	gnl\|CDD\|235821	PRK06522, PRK06522, 2-dehydropantoate 2-reductase; Reviewed.	2.92521e-53
NZ_CP040872.1\|WP_139417503.1\|2562618_2563509_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	5.23254e-86

>NZ_CP040872.1|WP_139417504.1|2563509_2563986_-|30S-ribosome-binding-factor-RbfA
MADPARARKMADRIKEIVAKRLDKGLRDPRLGFVTITDVRVTGDLQHASIFYTVYGTDEERQDSAKALKAATGMLRSEVGRNITARLTPSLEFIADAIPENAEHISALLREAQTRDAETAEFAATAEYAGEADPYVKPREYQDDDGADGRVDEADASR
>NZ_CP040872.1|WP_139417503.1|2562618_2563509_+|A/G-specific-adenine-glycosylase
MPRPPTPDTIATSVVDWFADAARPLPWRAAGVSPWAVLVSEFMLQQTQVARVVPRWEAWIARWPTAAALAAEPPSEAVRAWERLGYPRRALWLHRAAVEIVERHDGEVPADIDALLALQGIGPYTARAIAAFAFGARVPVVDTNTRRVIARAVAGQAEPGPPSTSRDLAAMAGLLPRDRDAARRFNAGAMELGATICTARSPRCDACPIAGACAWRAAGYPAYTGPRKAGQPRFEGSDRQVRGLVMRELRAAHRPVSRAEFEPLWADAAQLERALTTLVADGLAVGNPDGYRLPER
>NZ_CP040872.1|WP_139417502.1|2561966_2562569_-|uridine-kinase
MRLVTTPRVTFLRSIADEVLRHHGRGRMIVAIDGPLQSGKTAFGDDLAAVLEERDHSVFRASMEGFHRSREAQSVFGDDTPARYHRYGFDESALRRVLVEPFRLGGSTAFVTRVWDPARDAWVEPKWITGPDDAILIVDGRFLLRQRLAELWDVRIALDGDPVDPADVLAYAEGDPRLVASVVVDNRDPEHPKRGRSGRP
>NZ_CP040872.1|WP_139417501.1|2560394_2561693_-|LPXTG-cell-wall-anchor-domain-containing-protein
MSNPGAVPAHFDTDARTRVRWSSRRPFRRIAAILTSLALGAGLAVVGVVAPASAHTGDLIAKAACNPVTGEYDVTYSLKLSQASGKHGVTMWRVGTAAFDGTPKSDAGMDRGPVASDGNVTITLGTESLPGDTTTAPWVYAFTTWSDDFTKGSDGRVENLKGDCTTSGPEEIEVEGAPTFSDECGPGNEQVTLPDNTDFIEWTQAEQGGVITVTATARDGYVFAPGAKTTWNFEVDDEACTEASLDGSVVTGVCEADSPWIFFDVALTDPDDQVTDRNVRLVLSDGTDSETLDLGELDEQGLLQGKVLWPGASVDDEGNADGWPGWTRLDDGTWVETDGNFAWTRDLTNATIVVNPELPVELVYPEATPDCAVAPPTPGEPGGEGETPSTPAAGESLAHTGFAGTTIAIVAGLIVLAGAAFIVIARLRRKKS
>NZ_CP040872.1|WP_139417500.1|2559339_2560302_+|LysR-family-transcriptional-regulator
MRSFTDEVCDYAEMSTTTLRPPRPNPDDLLVLLAVSRTGRYTAAGAELGVNHTTIARRITALESALGGRVLARGADGWMLTALGEHAIAAAEGVERALDGLSPEDPRLAGVVRLSATDGFSGFIASPAIVAVRRKHPDVSLEIVAAQRRAAQHRMGVDLEVVVGTPHVHRAEAVHLADYALGLYASRSFLERHGTPRSPADLEGAPLVYFIESMLQVDALDEARRSTQGMIDAVSSTNVYVHVDATRAGAGFGLLPAFLADGHDDLERLFADEIDERLPYWLVCRPEALTQPVVLAFIEALRARIADVTDELLGRSARAA
>NZ_CP040872.1|WP_139417499.1|2558294_2559290_+|2-dehydropantoate-2-reductase
MRIGIIGAGALGGTFAVLLSRAGHEVEVTARGAGLEAIRVGGIRLTGGYGDLHVRVAAGTRLSVRPDLVLVCTKAQDAAAAIEGNAPLIDGATVVVVQNGLDGVVTAERLLPSSTCMGLLSIIAANYTEPGSVRVTTTAASYLGRGDGLADATCVRVAAILSEAVPVIAIDGFRGAQWTKLVVNMLNAVPAIVGRSVQEVVDDRRLRRVVTAEMRECVRVGIARGIRFGRLQGLGNLRLRLFARLPLVIGQVLPWLMRIRMGGNPNLGSTQQSVRRGQPTEIDHLNGVVVREAAAAGRVAPVNRALTALMHEVEDRGAFLPAERVLDAVRV
>NZ_CP040872.1|WP_139417498.1|2557230_2558259_+|branched-chain-amino-acid-ABC-transporter-permease
MSTDLETPIPTKFDVSDFDPQARRARSIRRILLGVVALVAVIGLPWWVYPPIAVDIAAWALFAISVDLLLGFVGLLSFGHAAFWGVSAYSAGLIAQNLGVPFPVAIIGGAIAAMIIAVPIGYLAVKRAGIYFAMVTLAFAQMIWFVANQWNDVTGGENGLQGVPKSFFGIELIETEAFYFYYVAVILIVLGAWLAWRIVNSPFGRVLVAIRDNPSRTRALGYDVERYKLIAFVLSAGIAGIAGGVFAISHGFVSLQELDWSTSGKVVLMTVLGGMGTLWGGPIGAAVIVLLEDRLATSGFDGIGIITGSIFILCVLLFRRGIWGTAKNLIDKATAAFAKRKG
>NZ_CP040872.1|WP_139417497.1|2556364_2557234_+|branched-chain-amino-acid-ABC-transporter-permease
MEAFLQYTVQGLAAGGFYALAALGLAVIFGALGVVNFAHGSFYMLGAVTAAVLLDVLDIHFWASLVIVPILMFIFGVIVELLLVQWLLKLDILYNFLLTFGLSLVLVDLVKRQYGVSGLPYEQPAGLDGLIRLGSVEIPAYQLFVFLFSLAVCLIVWLVLAKTRVGMIVRAATEEPERARALGINVSAWVTPVFGFGVALAGLAGVLAAPFRAVTATMGSNFVIILFAIVVIGGLGSVLGAVVAGFLVGLVEAYGQGYAGTFSQVLIFVLMAVVIMVRPAGLFGRKEAV
>NZ_CP040872.1|WP_139417496.1|2555048_2556296_+|ABC-transporter-substrate-binding-protein
MASTRRGLLGVTGFAASALLLAGCAGGPAPAAESELSDDKVVIGLLNDQSGVYKDLSGPNSEVAIEMAIEDYFAEYGDEAVVTEEQLEIVTADTQNKPDVANTQAQQMYDRSNADIILDVPASSAALAVAEVAAQKKKLYINVGAATMELTGAACNPYTFHWAYNTQMLAKGAAGVVEDGGETWSLVYPDYAFGQDMVKSFTGAVEDAGGTINESIATPFPNDNFSTFITRAASTNPDVVGIMAAGGDLINFVKQFNQSGVRDQATLAVGLMFITDIHSLGVEEFAGTTFTDAWYWNYDEQNREFADRFQKLTDTRPSFAHAANYSAAYQYLDAIQRAGTDDADAIVSELEGLKVNDVFLRNGEIRAGDHSVIHDSYVAKVKAADDVEEDWDYEEIIATIPAEDAFPDVNPDCSL
>NZ_CP040872.1|WP_139418437.1|2554257_2554950_+|ATP-binding-cassette-domain-containing-protein
MIEIGGLSAQYGEARVLNDVSLTVRPGEVVTLVGRNGAGKTTLLRSIMGLHRDLSGSIAYDGKQIETWSPNARARAGIGWVPDDRGIYASLTVAENLALPPVVHTDAWSMEQIHATFPRLRERRSSMGTQLSGGEQQMLAIARVLRMGSRLLLLDEPSEGLAPVIVQRIGEIIREITAQGVAVLLVEQNVKFASTVADRHYLLAQGRVVEQLSNADFLAREGELLEHLGM
>NZ_CP040872.1|WP_139417506.1|2566936_2567200_-|DUF448-domain-containing-protein
MEPVRTCIGCRSRAPRASLLRLVAQNSHVIADDEAVLPGRGAWLHPSLECYQLAVRRRAFGRALRIRGEVDTGNVENKLNGEVMTNE
>NZ_CP040872.1|WP_139417507.1|2567278_2568277_-|transcription-termination/antitermination-protein-NusA
MDIDLSVLRMMEREKEIPFDELVEIIEQAILMAYLKHTHPDQHGHANPEGARAHLDRKTGHVSVFVPELDEEGNVVGEAEGSPSDFGRIAAFAAKQVINQRLRDLADDAVLGEFRGREGDIVAGIIQQGPNPRMVHIDLGTVEAILPPEEQVAGEEYAHGQRIRVYVTSVAKGLKGPSITVSRTHPALVRKLFALEVPEIASGVVEIVSLAREAGHRTKIAVRATQPGVNAKGAAIGELGQRVRAVTAELGAEKIDIVDWNDDLATFVASALSPAKVTSAFVIDEGTRAVRALVPDYQLSLAIGKEGQNARLAAKLTGAKIDIQPDSALESD
>NZ_CP040872.1|WP_139417508.1|2570205_2570397_-|hypothetical-protein
MNGDDDEFEYPDTAGYPDGTGTLPEDVDDSDESADDSDDDLATELEGDLERFALADEEDDEGV
>NZ_CP040872.1|WP_139417509.1|2570471_2571602_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MPKVPEVLAPRRKSRQIKVGKVLVGGDAQVSVQSMTTTPTTNINATLQQIAELTASGCDIVRVAVPSRDDAEALPIIAKKSQIPVIADIHFQPNYVFAAIDAGCAAVRVNPGNIRKFDDRVGEIAAAAKAAGVSLRIGVNAGSLDPRLLEKYGKATPEALVESAVWEASLFEEHDFHDFKISVKHNDPIVMVKAYRQLAERGDWPLHLGVTEAGPEFQGTIKSATAFGILLGEGIGDTIRVSLSAPPVEEVKVGLQILQSLNLRERKLEIVSCPSCGRAQVDVYKLANDVTDGLEGMTVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESEIVATLIEEANRIADEMGADAPVGAPEVLTP
>NZ_CP040872.1|WP_139417510.1|2571672_2572392_-|hypothetical-protein
MTRNRRTAALTAAAVAILLGLGGCMGGSPAATSTPGTSPPPAESTPSASETPEDPLAQVTSVVLRPEALELRAGSELVVAIPYAGHESELVDALTRVSGVAPVVEDATPRESPPGTAYTWDAILYYDTAAAAEDENNPMVMPAWVRVTAPAFSSGVTLTTEQGYQVGDDVAAAIALGNPSMNGAGYGYYGAVEYGPVRGEHPYPASGVPFADAVVVDSGADGEAIEYLQAPLVLGLGGA
>NZ_CP040872.1|WP_139417511.1|2572953_2573688_-|hypothetical-protein
MDNSSAMRATIAAAATFVLATTLLAGCSAAPEPPSPSTVPSESPSSAPTPTVEPIDTVVAIVARPEALELRDASGGVVVELGYLGDVDSAIATIEGALGAAPVDEEYPGSSHVPPSTAHRWGAFELWEHRYVDNWADFATQERTLYMPSFGIMFTGPEVAGVALTTEQGVVAGSSWSVLEAMPGLQENPSGCSGPYLDFTSRDVTWPDGTVHEERHGVDFVATDDRSAIERVRAPLQVNQESCA
>NZ_CP040872.1|WP_139417512.1|2573708_2574137_-|hypothetical-protein
MFGRPGTQDAGSSQELPSAVRRWAGFELRERQYSDELPDAVQGPWYPNFRVVFTAAVSGDVRLETESGHVAGEPWADFAASPDANSNGLCEQRYGEIVVLSRTYSDGTMEDARNSVEFRASDDETIIASVTAPSVMHRDGCA
>NZ_CP040872.1|WP_139417513.1|2574308_2575358_-|alpha/beta-fold-hydrolase
MVDTIFPGIEVRRVRTPRLLANVLERPSDAPARTVVFVHGNVSSSLFWQPLMLTLPADVRALAVDLRGFGDSETLPVDATRGVRDFSDDVASVIDAMDLGEVHLVGWSLGGGVAMQLLLDRPELVATLTLQAPVSPDGFGGTRLDGGLLASDAAGTGGGGANPDFVARIARGDRSDEAGSPRAVFRSSYVVPGFESEHEDIWVESMLTTKTGVDNYPGDSAQSEHWPGFAPGGRGVLNTLAPTHFNTTAIVDLERKPPILWIHGTHDAIVGDASFFDLNQLGKAGLIPGWPGDDVAPPQPMIAQTRAVLARYSDSGGRVTELELENCGHSPHLEHPDAFRDALVAMLSD
>NZ_CP040872.1|WP_139418438.1|2575370_2575991_-|3-oxoacid-CoA-transferase-subunit-B
MAARAAKELPDGAYVNLGIGLPTLVPNYVPDGVTVVLQSENGILGVGPYPTEDTVDPDLINAGKETVTVLPGAAYFDSATSFGMIRGGKINAAILGAMQVSAAGDLANWMIPGKMVKGPGGAMDLVHGAQRLIILMEHVAKDGSAKIVNECSLPLTGRAVVHRIITDLAVIDVTPEGLKLVELSPGVTVDEVVAATEPSLDTTAFA
>NZ_CP040872.1|WP_139417514.1|2576013_2576787_-|3-oxoacid-CoA-transferase-subunit-A
MTLDKVVGSAGEAVADIPSGSSLAVGGFGLCGIPMVLIQALLDAGVDDLKVVSNNCGVDDWGLGVLLANRRISKMTSSYVGENKEFERQFLTGELELELTPQGTLAEKLRAGGSGIAAFFTQTGVGTQVAEGGLPRRYNPDGTISVASPVKPVQTFTVRGEDREFVLEEAITTDFALVHALRGDRHGNLVFDKSARNFSPLAAMSGRVCIAQVEELVEPGTIDPDHVHVPGVFVDRVVVVGPDIEKRIERRTVREEN

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Crispr_ID: NZ_CP040872_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040872_4

2779551-2779628

Orphan

Consensus_repeat	Method
CGCGCGCACGCGCGCCTTCCGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040872_4

>merge|NZ_CP040872|4|2779551-2779628|CRISPRCasFinder
CGCACGCACGCACTGCTTCCGCGCGACGCACCTTCCTCGCGCGCACGCGCGCCTTCCGCGCACGCACCTCTTCCGCGC

>NZ_CP040872|4|4|2779551-2779628|CRISPRCasFinder
CGCACGCACGCACTGCTTCCGCGC	GACGCACCTTCCTCGCGCGCACGCGCGCCT
TCCGCGCACGCACCTCTTCCGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040872.1\|WP_157008573.1\|2779843_2780536_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|223810
NZ_CP040872.1\|WP_139417673.1\|2785771_2786701_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223674
NZ_CP040872.1\|WP_139417664.1\|2772229_2774782_+\|penicillin-acylase-family-protein	unknown	unknown	gnl\|CDD\|376618
NZ_CP040872.1\|WP_139417674.1\|2786882_2788505_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853
NZ_CP040872.1\|WP_139418462.1\|2774766_2776065_-\|citrate-synthase	unknown	unknown	gnl\|CDD\|180164
NZ_CP040872.1\|WP_139417665.1\|2776259_2777375_-\|succinyldiaminopimelate-transaminase	unknown	unknown	gnl\|CDD\|236119
NZ_CP040872.1\|WP_139417672.1\|2784828_2785782_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224094
NZ_CP040872.1\|WP_139417668.1\|2778736_2779546_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|180270
NZ_CP040872.1\|WP_139417678.1\|2790316_2793205_-\|aminomethyl-transferring-glycine-dehydrogenase	unknown	unknown	gnl\|CDD\|235432
NZ_CP040872.1\|WP_139417666.1\|2777735_2778137_-\|histidinol-dehydrogenase	unknown	unknown	unknown
NZ_CP040872.1\|WP_056658762.1\|2777377_2777698_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|224069
NZ_CP040872.1\|WP_139417663.1\|2771082_2772048_+\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-succinyltransferase	unknown	unknown	gnl\|CDD\|274635
NZ_CP040872.1\|WP_139417676.1\|2789421_2789901_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417662.1\|2770371_2771016_+\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|377696
NZ_CP040872.1\|WP_139417671.1\|2783065_2784832_-\|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NZ_CP040872.1\|WP_139417667.1\|2778133_2778583_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417677.1\|2790006_2790294_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040872.1\|WP_139417661.1\|2769239_2770337_-\|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|237264
NZ_CP040872.1\|WP_139417670.1\|2780926_2782831_-\|translational-GTPase-TypA	unknown	unknown	gnl\|CDD\|224138
NZ_CP040872.1\|WP_139417675.1\|2788711_2789476_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806

Protein	Function_ID	Function_description	E-value
NZ_CP040872.1\|WP_157008573.1\|2779843_2780536_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	6.13574e-32
NZ_CP040872.1\|WP_139417673.1\|2785771_2786701_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.44702e-102
NZ_CP040872.1\|WP_139417664.1\|2772229_2774782_+\|penicillin-acylase-family-protein	gnl\|CDD\|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	2.9309e-171
NZ_CP040872.1\|WP_139417674.1\|2786882_2788505_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	3.94518e-135
NZ_CP040872.1\|WP_139418462.1\|2774766_2776065_-\|citrate-synthase	gnl\|CDD\|180164	PRK05614, gltA, citrate synthase.	0
NZ_CP040872.1\|WP_139417665.1\|2776259_2777375_-\|succinyldiaminopimelate-transaminase	gnl\|CDD\|236119	PRK07865, PRK07865, N-succinyldiaminopimelate aminotransferase; Reviewed.	0
NZ_CP040872.1\|WP_139417672.1\|2784828_2785782_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.64165e-87
NZ_CP040872.1\|WP_139417668.1\|2778736_2779546_+\|enoyl-CoA-hydratase	gnl\|CDD\|180270	PRK05809, PRK05809, short-chain-enoyl-CoA hydratase.	1.69564e-78
NZ_CP040872.1\|WP_139417678.1\|2790316_2793205_-\|aminomethyl-transferring-glycine-dehydrogenase	gnl\|CDD\|235432	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase.	0
NZ_CP040872.1\|WP_056658762.1\|2777377_2777698_-\|ferredoxin-family-protein	gnl\|CDD\|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	4.19498e-10
NZ_CP040872.1\|WP_139417663.1\|2771082_2772048_+\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-succinyltransferase	gnl\|CDD\|274635	TIGR03535, DapD_actino, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. This model represents a clade of the enzyme specific to Actinobacteria. Alternate name: tetrahydrodipicolinate N-succinyltransferase.	1.06028e-163
NZ_CP040872.1\|WP_139417662.1\|2770371_2771016_+\|DUF1211-domain-containing-protein	gnl\|CDD\|377696	pfam06736, DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins.	1.68143e-26
NZ_CP040872.1\|WP_139417671.1\|2783065_2784832_-\|dipeptide-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NZ_CP040872.1\|WP_139417661.1\|2769239_2770337_-\|succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|237264	PRK13007, PRK13007, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NZ_CP040872.1\|WP_139417670.1\|2780926_2782831_-\|translational-GTPase-TypA	gnl\|CDD\|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NZ_CP040872.1\|WP_139417675.1\|2788711_2789476_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	6.99306e-11

>NZ_CP040872.1|WP_139417668.1|2778736_2779546_+|enoyl-CoA-hydratase
MAEPSTQENGPDVRVERDGGIAIVTIDRPRALNALSPEVLSTILGTFEALAAEGSDVRGVLLTGAGGRAFVAGADIRAMAQFTPEQAEETARLGHRVAAAIEGLAAPVIACVDGFALGGGLELALACDFIYATDASSFGQPEVHLGLIPGFGGTVRLPRAVGLARAKELIYTGRRIDTAEALAIGLVARSFADRESLFAGARATLDEVGANAAPAVGLAKRVLVDAAGRRTESATELEVAGFGDAFRTQDMREGVAAFVEKREPEFTGA
>NZ_CP040872.1|WP_139417667.1|2778133_2778583_-|hypothetical-protein
MRQSTTSRRLGAAALIAALAVTGLSACFPNPADLVEQGVEDAVEGATGGDVSLGGELPDGFPESVALVDGDITFAAGAGGSEGWIVMIASTAADPVADAAAKLEAAGFTEDTTLSGEGASAVVYSNGEYFVLVAGEGEAVSYTVTPQTK
>NZ_CP040872.1|WP_139417666.1|2777735_2778137_-|histidinol-dehydrogenase
MTSRGSRIGTIVVAFLIGLFYGALGTVGHRTSWTIGEIAVPWGLVAALVGVAGLLLGIRLVAGGRGAAAAAGAGIVVAVAVLTLPGPGGSVLIVGDLTGTVWSIAPALIAVLVVAWPKLPKPRPRDAETLRDA
>NZ_CP040872.1|WP_056658762.1|2777377_2777698_-|ferredoxin-family-protein
MTYVIALPCVDVKDRACIDECPVDCIYEGERSLYIHPDECVDCGACEPVCPVEAIYYEDDLPEMWADYYKANVEFFDDIGSPGGAAKIGVIPKDHPVIAVLPPQAH
>NZ_CP040872.1|WP_139417665.1|2776259_2777375_-|succinyldiaminopimelate-transaminase
MARGELPDYPWDLMVPFRERAAVHPDGVVDLSIGSPVDPTPALVRTALANATDAHAYPQTIGTDELRSAIIDWFARRRGVTGLTSANVLPTVGSKELVALLPFLLGLGEGDVVVHPRAAYPSYEMGAVLVGATAMASDDPAEWPAETKLVWLNSPGNPDGRVLTIDELRTARERALELDAIIVGDECYAELGWEGEWADAPAPSLLDPRVVGESRHQVLVAYSLSKQSNMAGYRTAFIAGCAAVIGRITTVRKHAGLMLPQPLQAAMIAALRDDVHVAEQKERYRARRDLLKPALEAAGFRIDRSEAGLYLWATEGRAAWESIGRLADLGIVAGPGIFYGPHHPEHVRLSLTATDERISAASERLRAAAPA
>NZ_CP040872.1|WP_139418462.1|2774766_2776065_-|citrate-synthase
MKNAAGQTPQTATLSYGGTTAELPVQRAVQGNSSIDVSTLTRQTGLTALDYGFVNTASTRSAITYIDGEQGILRYRGYPIEELAANSTFLEVAWLLIYGELPTADQLGEFDEKIRRHTLLHEDLKRFFSSLPHTAHPMSVLSSAVSALSTYYEDSTDSNDPEQVELTMVRLLAKLPVIAAYAHKKSIGQAFLYPDNSLSFVDNFLKLNFGNMAEPFGVDPVLSTALDRLLILHEDHEQNASTSTVRLVGSTGANLYASISAGIQALSGPLHGGANEAVLQMLGRIRDSGEGVEKFVERVKNKEDGVKLMGFGHRVYKNYDPRATIVKQSADEVLAGLGVADPLLDIAKELEQFALQDDYFKERRLYPNVDFYTGVIYKAMGFPTRMFTVLFAIGRLPGWMAHWREMNLDPQTKIGRPQQLYIGEPERHYPSA
>NZ_CP040872.1|WP_139417664.1|2772229_2774782_+|penicillin-acylase-family-protein
MKFVIGLLITVLVLAIVAAGLGWWTVHRSFPTLNGAVDVPGLGAEVTVIRDDAGIPQLYAETDHDLFFAQGYVHAQDRFWEMDFRRHVTSGRLAELFGESQVGTDAFIRTLDWRGIAEQEYEALASAPKAYYDAYAEGVNAYLGERSGADLSLEYAVLGLQNPGYSPEPWTGVDSIAWLKAMAWDLRSNLGDEIDRAMLSTALPPEEVARLHPEFPWGTMPTIVGEQPAAAPAGLSSTRLPGDVDASETDAAAASAPVSDYVAALATLRATIDGVPELLGPEGGDIGSNSWVVSGALTESGLPLLANDPHLGPTMPSIWTQMGLHCVEITETCGFDVAGFSFSGLPGIVIGQNASIAWGFTNLGPDVADLYLERLDGDSYELDGALVPLTLREETIEVAGGDPVTITVRSTDRGPIVTDISTDFGEVAAQFPAASGQPDGTYEVSLQWTALTPGTTAGAIFALDRAQDWNGFRAAAALFDVPAQNLIYADVAGNIGYQAPGRIPVRTSGDGTLPVPGWTSENGWSGTIPFDELPSVLNPAAGYIVTANNAAAGPDGPMLTKDWDYGYRAAGIDRLIRERIDSGEKFTVDSLAEIQLDTADANAEAFLPVIASLEVDGDAARGAELLGGWNGNADVDSAQAAYFAVFWRTLLDDMFGELPEAALPQGGDRWFNVVGTLLGEPDAAWWTNEDLGVAGRDAMIANALDAAWKEAEQRMGSNPDSWRWGRLHTLTLTNQSFGESGIAPIEWLFNRGPYELGGGSAIVNAIGWDARFGYAVDWVPSMRMVVDLADRDASRWINLTGASGHAFHANYADQAPLWQRGELLDWPFTREGVEADARDTLTLQPAQAEG
>NZ_CP040872.1|WP_139417663.1|2771082_2772048_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-succinyltransferase
MPANDASTPPARTAHGAGLATVAADGTVLDAWFPNPELVGEGGAEASALAPAHLELARPDDRRNVTVEAVDFTIDLDAAPDGTADAYLRLHLLSHLVVRPNTINLDGIFAHLPSVVWTNGGPVHPDDFTRLRPALQRAGIHAEGLDKFPRLLDYVTPDRVRIADAARVRLGAHLAPGTTVMHEGFVNFNAGTLGASMVEGRISQGVVVGDGSDIGGGASIMGTLSGGGTQRIEIGERALLGANSGIGISIGDDSVVEAGLYVTAGTKVVLLGGKGERPSTVKAVVLSGVPNLLFRRNSLNGQVEALSRSGDGVQLNTALHA
>NZ_CP040872.1|WP_139417662.1|2770371_2771016_+|DUF1211-domain-containing-protein
MIRRRQHPDATQATTRLEAFTDGVFAIAATLLVLDLTTHALGEVDSDAQLWAALGGMWELFLNFGVSFIVLCLLWMTHVQQFESIARVDAVMTWLNNGRLLFVVLVPFTTGVATEYSEYYAGRMLMPITFFLAILFSWLQWRWAVHHRSDLMPDLPEQDVRTLDRGSLSAVILATSVVVLSPWLGSAAFLMFTLDSLLTRALRTRSAGAGTTTG
>NZ_CP040872.1|WP_139417661.1|2769239_2770337_-|succinyl-diaminopimelate-desuccinylase
MPAHTPLTLDLAADSVAITQAICDVPSVSGDETLLADLVEQAFAGASHLEVFRDGDTVVARTNLGRERRVVIAGHLDTVPINGNVPTRFETEDGVDYLWGRGTVDMKAGVAVQLKLALELTEPVVDVTWMWYDNEEVAASLNGLGRLSRNRPDLFAGDFAILGEPSNGQVEGGCNGTLRAEVRTAGLRAHSARSWVGENAIHKLAPALTRLAEYEAETVEVDGLAYREGLNAVLVSGGIAGNVIPDEAVLTVNYRFAPSRSVAEASALVTSFFDGFDVAIVDSAEGARPGLDDPLAQQFVRAVGAEPRPKYGWTDVARFSALGIPAVNFGPGDPLKAHADDERVDVRQIRHTETALRAWLTGVTA
>NZ_CP040872.1|WP_157008573.1|2779843_2780536_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MFSVIAMSFAAAMMVATSLPSLAVSATDTEARASVYAPAEDTIEYTPQTVEVGGEGVMSQLAAEPYDVVAAPPPIVSEVASLGNVALVDTDTIVWPVLTPENRSSGFGPRAAPCSGCSTNHDGVDFNPGNGTPVMSIADGVVVLATENGGGLGVNIEVQHNIGGELITSSYGHMQIGSMTVSVGQQVTAGQVIGLVGSTGQSTGPHLHLEMFGEDGVRFDGFAWLSARLG
>NZ_CP040872.1|WP_139417670.1|2780926_2782831_-|translational-GTPase-TypA
MANATRNDLRNVAIVAHVDHGKTTLVDAMLNQTNSFDAHAHVEERAMDSNELEREKGITILAKNTAISYRGTHAADGPITINVIDTPGHADFGGEVERGLSMVDGVVLLVDSSEGPLPQTRFVLRKALEARMPVILLVNKTDRPDARIDEVVAESQDLLLGLASDMADDVPDLDLDAILDVPVVYASGRNGAASHNKPGNGELPDNDDLEPLFESILQHIPAPTYDDEHPLQAHVTNLDASPFLGRLALLRVFHGTIKKGQTVAWVKHDGSVQNVRVTELFLTKALDRYPAESAGPGDIAVVAGFEDIMIGDTLADADDVRALPIIAVDEPAISMTIGTNTSPLVGKVKGHKLTARMVKDRLDRELVGNVSLKILDIGRPDAWEVQGRGELALAILVEQMRREGFELTVGKPQVVTKQVDGKTHEPYEHLTIDAPEEYLGAITQLLAARKGRMDNMSNHGTGWVRMEFIVPSRGLIGFRTEFMTTTRGTGIANAISHGYDAWAGQIVTRNNGSIVADRSGVVTPFAIIALQERMTFFVNPTEEVYEGMVIGENSRADDMDVNITKEKKLTNMRSSTADTFESMTPSRQLSLEECLEFAREDECVEVTPAAVRIRKVELDATARARATSRLKKQG
>NZ_CP040872.1|WP_139417671.1|2783065_2784832_-|dipeptide-ABC-transporter-ATP-binding-protein
MSETTNGAGMHDSSAGEERPLLEIKNLQVGFNTQDGVLKAVDGANITLYRGQSLAIVGESGSGKSTTAHAIINLLPGTGHISGGQILLDGQDLTKASAKEMEGIRGRKIGFVPQDPMSNLNPVWSIGFQVEEAIQANGIATGRKEVKKRAIEVLKQAGLHDADRRLKQFPHQFSGGMRQRVLIGMGLAANPQLLIADEPTSALDVTVQRVILDHLESLTRELGTTLLFITHDLGLAAERAEQLVVMYKGRIVESGPSAQILQNPQHPYTQRLVAAAPSLASRRIQATGSISAAESSMSDDAASAAGDSIDLLATAEARAEALAAAESAPPAIVVEDLTKVFKIRGSGEFTAVDQVSFQIPKGTTMALVGESGSGKSTVAKLLLKLEDATSGKIVVGGKDLAATSGKELFELRGRMQPVFQDPYGTLNPLRNIGNTISEPLFTHKVGTNASRRERVFELLEQVSLPRTLVGRYPNELSGGQRQRIAIARALALKPEILVLDEAVSALDVLVQAQILRLLADLQAELGLTYLFITHDLAVVRVIADRVCVMQRGKIVESATTDEVFDHPQEQYTKDLLAAIPGANIQLGA
>NZ_CP040872.1|WP_139417672.1|2784828_2785782_-|ABC-transporter-permease-subunit
MPSKTRPNQEHFVAPLEETPLVAIDSVKTEGKPSNLWRDAWADVRKRPMFWISAALIVLVVVVALFPNWFTQVPPNNDCQLANSNGGPTAGHPLGFTKQGCDIYSRIIHGTSTSLSVGLIVTFLVAFLGIVFGAFSGFYGGWIDSVLSRIGDIFFSIPYILAAVVVMSVMSKYASVWVISLAIGLFAWPSTARVLRAEILRVKNSDFVMAATALGVSKFRILLRHVLPNSIAPVIVITTLSLAAAIVAEASLSFLGVGLPSTTMSWGNDISAAQNDLRQAPQTLILPSIALSITVLSFIMLGEVIRDALDPKARAQR
>NZ_CP040872.1|WP_139417673.1|2785771_2786701_-|ABC-transporter-permease-subunit
MAGYIVRRLLQVIPVLLGTTFLIYFMVFAMPGDPVVGLFGDKTPPPAVVEELRARYNLDKPFIVQYLLFLGNILRGDLGVSFSGQPVADILAQTFPVTLRLAMLSVFFLMVAGISVGLVSGLRKGGIFDASALVVSLMLISVPIFVVGFVAQYVFAIQLGWFRPTVGFGAPWSELVLPALVLATGSFAQIVRLTRSSVIETEGQDFVRTAASKGLSRRRIVPVHILRNSLIPVVTYLAVDFGVLMVGAVITEGIFNVPGVGRTVYQAIIRGENPTVVAFVTIMVLIYLVVNLLIDLFYAVLDPRIRYAK
>NZ_CP040872.1|WP_139417674.1|2786882_2788505_-|ABC-transporter-substrate-binding-protein
MKIKRIGVVAIALAAAGALTLSGCTSGDTGATDESGSSTAIITTNGSEPQNPLIPTNTNEVGGGKILDSIFAGLIFYDADGAPVNDMAESIETEDAQHYTIKIKADQTFSNGEPVTANSFVDAWNYGAALDNAQLSSYFFESIEGFSYDVNVPELPGLVVVDDLTFEVTLSQPESDFPLRLGYSAFFPLPESAWEDLEAFGENPIGNGPYMLDGEGAWKHNEKIDLVVNPDYQGPRQPANGGLDIIFYATQDASYADLQGGNVDVVDQIPPSALGTYEDEFGDRSVNQAAAIFQSFTIPARLPHFSGEEGELRRAAISKAINREEITDVIFEGAATATHDFTSPVIDGYSEEIPGSDVLDFDADAAKDLWAQADAIAPWTGTFQIGYNADGGHQAWVDAVANQLKNNLGIEASGNPFPTFAEFRTSVTDRAIQTPFRSGWQADYPALFNFLGPIYGTGAGSNDGDYSNPEFDTLLTEGLAETEIDAANEKFQQAQEILFKDLPAIPLWYRTVNGAWSEQVENVQYGWNSVPLYYQITKSE
>NZ_CP040872.1|WP_139417675.1|2788711_2789476_+|CPBP-family-intramembrane-metalloprotease
MSSAARLRLEVGIVFGLSLGASAVYSIVSIVAKLTEETPLGEQTVALNPSRAPREWLDFTYQFLDVFFGLFAVALVLYLLWAPGTNPFRRIGLDLSRPGRDAASGVLLVLAIGVPGLALYALGRALGLTVAVEASPADWLWWTVPVLIFRALEAALVEEVIVVGYLFTRFRELGVGPWATIVSSALLRGTYHLYQGIGPFFGNVAMGVVFGWCYQRWGRTMPLVIAHWILDIVSFVGYPLAVGWWPGLFTVSTG
>NZ_CP040872.1|WP_139417676.1|2789421_2789901_-|hypothetical-protein
MAPGSLEAGGMMFVDFIGVVATLGFVGLLVGTTVLAGRGLGLEQRAGLLERRDPATAEALRRAQSITGFGGGAFGDEGYYSTVCTPSRRSGLDLARVRGTDPDLRVEAAEEALPPMPATVVVLGRSEHVPRTLRAGHANRRSQPVETVKSPGHQPTASG
>NZ_CP040872.1|WP_139417677.1|2790006_2790294_+|hypothetical-protein
MEESSVEGTGLNGTMLLAQALAVGLIAARATDRRFGIDRAARREAQRRETEVLAAERRLRAPRARRHTLSQEPPPEIALFSGETGRFQPNRPEDS
>NZ_CP040872.1|WP_139417678.1|2790316_2793205_-|aminomethyl-transferring-glycine-dehydrogenase
MTVSSAFDLDAFGRRHIGTSPSDHGLMLAELGYDSLDSLMAAAVPTSIRMGDVLNSAIPPAATEREALEELASLASQNTVRTSMIGLGYYGTVTPAVIQRNVLENPGWYTAYTPYQPEISQGRLEALINFQTLVCDLTGLDTANSSMLDEGTAVVEGMLLARRASKSTSNRFIVDADLFPQTLALLESRAEAVGIELVVADLGEATDVADLGEHFGLFVQYPGASGRVWNPASVIAASKAQGGLVVVAADLLALALITSPGELGADIAVGTSQRFGVPMGFGGPHAGYMAVRAGLERQLPGRLVGVSKDVAGAPAYRLTLQAREQHIRREKATSNICTAQVLLAVMASMYAVYHGPRGIRHIATQVAAKARLLAGWLEEIGQHVAHDAYFDTLRVHVPGIAKHVVERARALGIDVWEADDATVQVSVDETTTWEDLQAVVRAFGFDDAPFRAGSGSLPNAIPEALRRTSSYLEHPVFNTHQSETQMMRYLKQLADRDYALDRGMIPLGSCTMKLNAATEMQAVTWPAFANLHPFAPAADAVGSLGLIEQLETWLAEVTGYDTVSLQPNAGSQGELAGLLAIRGFHHANGEDERTVCLIPSSAHGTNAASAVLAGMRVVVVATDALGNVDLDDLRAKIAEHAETLAALMITYPSTHGVYEHEVKDIAQAVHDAGGQVYVDGANLNALLGFARFGDFGGDVSHLNLHKTFCIPHGGGGPGVGPVAAKAHLAPYLPGHPMAQRADHSGGFVHGGGPVSAAPYGSPSILPISWAYVRMMGSEGLKQATATAVLAANFVASRLREHFPVLYTGDNGLVAHECILDLRPLTAATGVSVDDVAKRLVDYGFHAPTMSFPVAGTLMVEPTESEDLAELERFVEAMVAIKAEADAVASGEWPADDNPLVNAPHTAESVITGEWTHPYTREQAVYPVHSLVRGKYWAPVRRVDQAYGDRNLVCACPPIEAFA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	620519-620548	6	0.8
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	556130-556159	6	0.8
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1477637-1477666	7	0.767
NZ_CP040872_3	3.1\|2566275\|34\|NZ_CP040872\|CRISPRCasFinder	2566275-2566308	34	NZ_CP045204	Citrobacter sp. NMI7904_11 plasmid pCTEL-1, complete sequence	5001-5034	8	0.765
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	381915-381944	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NC_004041	Rhizobium etli CFN 42 plasmid p42d, complete sequence	62217-62246	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP020898	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRetBra5b, complete sequence	42009-42038	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP021027	Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence	80519-80548	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013633	Rhizobium sp. N324 plasmid pRspN324c, complete sequence	90833-90862	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	121754-121783	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP020950	Rhizobium sp. CIAT894 plasmid pRheCIAT894c, complete sequence	130657-130686	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013587	Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence	64702-64731	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013598	Rhizobium sp. N741 plasmid pRspN741c, complete sequence	99141-99170	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013561	Rhizobium phaseoli strain N841 plasmid pRphaN841d, complete sequence	92830-92859	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	121363-121392	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013550	Rhizobium phaseoli strain R611 plasmid pRetR611c, complete sequence	86372-86401	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013530	Rhizobium phaseoli strain R723 plasmid pRphaR723c, complete sequence	86373-86402	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013535	Rhizobium phaseoli strain R650 plasmid pRphaR650c, complete sequence	86372-86401	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013540	Rhizobium phaseoli strain R630 plasmid pRphaR630c, complete sequence	103356-103385	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013544	Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence	31993-32022	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	121754-121783	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013502	Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence	99062-99091	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013583	Rhizobium phaseoli strain N261 plasmid pRphaN261c, complete sequence	86373-86402	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013508	Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence	99141-99170	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013519	Rhizobium sp. N113 plasmid pRspN113b, complete sequence	99140-99169	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	121363-121392	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP021125	Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence	91426-91455	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013492	Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence	99138-99167	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013514	Rhizobium sp. N1314 plasmid pRspN1314c, complete sequence	92829-92858	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013497	Rhizobium sp. N621 plasmid pRspN621b, complete sequence	99138-99167	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013592	Rhizobium sp. N871 plasmid pRspN871b, complete sequence	99062-99091	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	CP007643	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence	88288-88317	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NC_010996	Rhizobium etli CIAT 652 plasmid pB, complete sequence	96841-96870	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP013604	Rhizobium sp. N731 plasmid pRspN731c, complete sequence	92829-92858	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	356292-356321	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP017243	Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence	78982-79011	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	412974-413003	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	264428-264457	8	0.733
NZ_CP040872_4	4.1\|2779575\|30\|NZ_CP040872\|CRISPRCasFinder	2779575-2779604	30	KR080206	Mycobacterium phage ShedlockHolmes, complete genome	55896-55925	8	0.733
NZ_CP040872_3	3.1\|2566275\|34\|NZ_CP040872\|CRISPRCasFinder	2566275-2566308	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1353743-1353776	9	0.735

1. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.8

-gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
tcatg-accttcatcgcgcgcacgagcgccg	Protospacer
  *.* ****** *********** *****

2. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
gttgcaccttcttcgcgcgaacgcgcgtca	Protospacer
* .********.******* *******.*

3. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
atcgcgccttcctcgcgcgctcgcgcaacc	Protospacer
. ***.************** *****. *.

4. spacer 3.1|2566275|34|NZ_CP040872|CRISPRCasFinder matches to NZ_CP045204 (Citrobacter sp. NMI7904_11 plasmid pCTEL-1, complete sequence) position: , mismatch: 8, identity: 0.765

aggctgggccgggcgcgagcccatgccctgcgag	CRISPR spacer
ggcccgctccgggcgcgtgcccttgccctgcgcg	Protospacer
.* *.*  ********* **** ********* *

5. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
acggcaacttcctcgtgcgcacgcgcgagc	Protospacer
.  *** ********.***********  .

6. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NC_004041 (Rhizobium etli CFN 42 plasmid p42d, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

7. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP020898 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRetBra5b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

8. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP021027 (Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

9. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013633 (Rhizobium sp. N324 plasmid pRspN324c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

10. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

11. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP020950 (Rhizobium sp. CIAT894 plasmid pRheCIAT894c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

12. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013587 (Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

13. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013598 (Rhizobium sp. N741 plasmid pRspN741c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

14. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013561 (Rhizobium phaseoli strain N841 plasmid pRphaN841d, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

15. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

16. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013550 (Rhizobium phaseoli strain R611 plasmid pRetR611c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

17. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013530 (Rhizobium phaseoli strain R723 plasmid pRphaR723c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

18. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013535 (Rhizobium phaseoli strain R650 plasmid pRphaR650c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

19. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013540 (Rhizobium phaseoli strain R630 plasmid pRphaR630c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

20. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013544 (Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

21. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

22. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013502 (Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

23. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013583 (Rhizobium phaseoli strain N261 plasmid pRphaN261c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

24. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013508 (Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

25. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013519 (Rhizobium sp. N113 plasmid pRspN113b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

26. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

27. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP021125 (Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

28. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013492 (Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

29. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013514 (Rhizobium sp. N1314 plasmid pRspN1314c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

30. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013497 (Rhizobium sp. N621 plasmid pRspN621b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

31. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013592 (Rhizobium sp. N871 plasmid pRspN871b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

32. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to CP007643 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

33. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NC_010996 (Rhizobium etli CIAT 652 plasmid pB, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

34. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP013604 (Rhizobium sp. N731 plasmid pRspN731c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

35. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
acggcaacttcctcgtgcgcacgcgcgagc	Protospacer
.  *** ********.***********  .

36. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP017243 (Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
attccaccttcctcgggcgcacgggcgcaa	Protospacer
. . *********** ******* ****

37. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
cgcaaaccctcctcgcgcgcacgcgcctcc	Protospacer
 .*. ***.***************** .*.

38. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
cgcaaaccctcctcgcgcgcacgcgcctcc	Protospacer
 .*. ***.***************** .*.

39. spacer 4.1|2779575|30|NZ_CP040872|CRISPRCasFinder matches to KR080206 (Mycobacterium phage ShedlockHolmes, complete genome) position: , mismatch: 8, identity: 0.733

gacgcaccttcctcgcgcgcacgcgcgcct	CRISPR spacer
gcttgaccttgctcgcgctcacgcgcgcac	Protospacer
* .  ***** ******* ********* .

40. spacer 3.1|2566275|34|NZ_CP040872|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 9, identity: 0.735

aggctgggccgggcgcgagcccatgccctgcgag	CRISPR spacer
caccatggccaggcgccagcccatgccctgcgtc	Protospacer
 . *  ****.***** ***************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage