CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP040999	Staphylococcus aureus strain FDAARGOS_773 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	0	2
NZ_CP040998	Staphylococcus aureus strain FDAARGOS_773 chromosome, complete genome	13 crisprs	DinG,DEDDh,cas3,WYL,csa3	12	5	8
NZ_CP041000	Staphylococcus aureus strain FDAARGOS_773 plasmid unnamed2	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 3637

Bacillus_virus(100.0%)

bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000726502.1\|381_675_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000713732.1\|749_2684_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000831610.1\|2687_2999_+	YxeA family protein	NA	NA	NA	NA
WP_000593106.1\|3010_3637_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.1e-22	33.7

DBSCAN-SWA_2

14179 : 27079

Staphylococcus_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000690626.1\|14179_14755_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	2.9e-42	51.7
WP_000069452.1\|15021_17067_+	copper-translocating P-type ATPase CopB	A0A218MNH6	uncultured_virus	1.0e-70	31.0
WP_000277154.1\|17081_18515_+	multi-copper oxidase Mco	NA	NA	NA	NA
WP_000277738.1\|18581_20228_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.0e-289	98.4
WP_000378396.1\|20590_22771_-	cadmium-translocating P-type ATPase CadA	E4ZFI9	Streptococcus_phage	9.3e-251	63.7
WP_000159128.1\|22763_23129_-	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	8.5e-24	47.8
WP_000361064.1\|23366_23744_-	hypothetical protein	NA	NA	NA	NA
WP_001105942.1\|23838_24513_+\|transposase	IS6-like element ISSau6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.3e-113	88.4
WP_001035802.1\|24547_24760_-	hypothetical protein	NA	NA	NA	NA
WP_000120605.1\|25475_25790_+	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4PQT4	Staphylococcus_phage	4.7e-39	73.1
WP_000153630.1\|25789_27079_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	6.6e-188	81.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP040998

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040998_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_1

579698-579884

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCC	CRT

3 spacers

The CRISPR arrays of NZ_CP040998_1

>merge|NZ_CP040998|1|579698-579884|CRT
TCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCACTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCACCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCC

>NZ_CP040998|1|1|579698-579884|CRT
TCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTC
ACTATGTTGGGGCCCCGCC	AACTTGCACATTATTGTAAGCTGACTTTTCGTCAGCT
TCTGTGTTGGGGCCCACCC	CAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTC
TCTATGTTGGGGCCCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000791587.1\|584785_585283_-\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_CP040998.1\|WP_001239285.1\|571204_572152_+\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_CP040998.1\|WP_001063559.1\|577933_578659_+\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP040998.1\|WP_000231632.1\|582475_582709_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_001074342.1\|574719_575652_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP040998.1\|WP_000739523.1\|577113_577839_+\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP040998.1\|WP_000793605.1\|575674_576676_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP040998.1\|WP_000398672.1\|569721_569856_-\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_CP040998.1\|WP_001791789.1\|587080_587173_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000765708.1\|580220_580367_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_001823392.1\|572991_574497_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP040998.1\|WP_000739209.1\|587489_587819_-\|complement-convertase-inhibitor-Ecb	unknown	unknown	gnl\|CDD\|289007
NZ_CP040998.1\|WP_000149423.1\|572456_572684_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000669537.1\|584281_584632_-\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_CP040998.1\|WP_001245802.1\|570767_570956_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_CP040998.1\|WP_000857483.1\|581039_581999_+\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388
NZ_CP040998.1\|WP_000041896.1\|578766_579483_+\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_CP040998.1\|WP_000739563.1\|586719_587121_+\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_CP040998.1\|WP_001032814.1\|583330_583516_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_001802045.1\|580039_580264_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000791587.1\|584785_585283_-\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
NZ_CP040998.1\|WP_001239285.1\|571204_572152_+\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.44089e-84
NZ_CP040998.1\|WP_001063559.1\|577933_578659_+\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_CP040998.1\|WP_001074342.1\|574719_575652_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP040998.1\|WP_000739523.1\|577113_577839_+\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_CP040998.1\|WP_000793605.1\|575674_576676_-\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP040998.1\|WP_000398672.1\|569721_569856_-\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_CP040998.1\|WP_001823392.1\|572991_574497_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_CP040998.1\|WP_000669537.1\|584281_584632_-\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_CP040998.1\|WP_001245802.1\|570767_570956_-\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_CP040998.1\|WP_000857483.1\|581039_581999_+\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.27434e-141
NZ_CP040998.1\|WP_000041896.1\|578766_579483_+\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
NZ_CP040998.1\|WP_000739563.1\|586719_587121_+\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	3.87075e-77
NZ_CP040998.1\|WP_000739209.1\|587489_587819_-\|complement-convertase-inhibitor-Ecb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	4.63429e-22

>NZ_CP040998.1|WP_000041896.1|578766_579483_+|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_CP040998.1|WP_001063559.1|577933_578659_+|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP040998.1|WP_000739523.1|577113_577839_+|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_CP040998.1|WP_000793605.1|575674_576676_-|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP040998.1|WP_001074342.1|574719_575652_-|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_CP040998.1|WP_001823392.1|572991_574497_-|YfcC-family-protein
MPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_CP040998.1|WP_000149423.1|572456_572684_-|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_CP040998.1|WP_001239285.1|571204_572152_+|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_CP040998.1|WP_001245802.1|570767_570956_-|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_CP040998.1|WP_000398672.1|569721_569856_-|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
>NZ_CP040998.1|WP_001802045.1|580039_580264_-|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_CP040998.1|WP_000765708.1|580220_580367_-|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP040998.1|WP_000857483.1|581039_581999_+|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NZ_CP040998.1|WP_000231632.1|582475_582709_+|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP040998.1|WP_001032814.1|583330_583516_+|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP040998.1|WP_000669537.1|584281_584632_-|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_CP040998.1|WP_000791587.1|584785_585283_-|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NZ_CP040998.1|WP_000739563.1|586719_587121_+|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
>NZ_CP040998.1|WP_001791789.1|587080_587173_+|hypothetical-protein
MLKTVKSTRLLGIKKHTELNSCTPNVRKQC
>NZ_CP040998.1|WP_000739209.1|587489_587819_-|complement-convertase-inhibitor-Ecb
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNVEAAKKYDQYQTNFKKQVNKKVVDAQKAVNFFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP040998_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_2

797659-797967

Orphan

Consensus_repeat	Method
CCAACTTGCANNNTNTNNNNAGCTGNCTTT	CRT
CCAGCCTCTGTGTTGGGGCCCCG	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP040998_2

>merge|NZ_CP040998|2|797659-797967|CRT,CRISPRCasFinder
CCAAATTGAAATTATCCTACTGCTGTCTTTTTGGGAGTGGGACAGAAATGATATTTTCGCAAAATTTATTTCGTCGTCCCACCCCAACTTGCACACTATTGTAAGCTGACTTTTCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAAATTGAGGAGCTAATTTCTCTGTGTCGGGGCTCCACCCCAACTTGCACACTATTGTAAGCTGACTTTCCGCCAGCCTCTGTGTTGGGGCCCCGCCAACTTGCACACTATTGTAAGCTGACTTTCCACCAGCCTCTGTGTTGGGGCCCCG

>NZ_CP040998|2|2|797659-797941|CRT
CCAAATTGAAATTATCCTACTGCTGTCTTT	TTGGGAGTGGGACAGAAATGATATTTTCGCAAAATTTATTTCGTCGTCCCACC
CCAACTTGCACACTATTGTAAGCTGACTTT	TCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCATTGTCTGTAGAAATTGAGGA	GCTAATTTCTCTGTGTCGGGGCTCCACC
CCAACTTGCACACTATTGTAAGCTGACTTT	CCGCCAGCCTCTGTGTTGGGGCCCCG
CCAACTTGCACACTATTGTAAGCTGACTTT

>NZ_CP040998|2|1|797889-797967|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCG	CCAACTTGCACACTATTGTAAGCTGACTTTCCA
CCAGCCTCTGTGTTGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000781156.1\|803881_804265_+\|kinase	unknown	unknown	gnl\|CDD\|378054
NZ_CP040998.1\|WP_011443624.1\|807233_807563_+\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
NZ_CP040998.1\|WP_000035058.1\|803224_803818_-\|peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|238908
NZ_CP040998.1\|WP_000838037.1\|800942_802070_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_CP040998.1\|WP_000138487.1\|798091_799336_-\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_CP040998.1\|WP_000154930.1\|782851_786505_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP040998.1\|WP_000711486.1\|790141_790717_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP040998.1\|WP_000007967.1\|791261_791837_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP040998.1\|WP_000172342.1\|786505_789982_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_CP040998.1\|WP_000573077.1\|807555_809052_+\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
NZ_CP040998.1\|WP_000054609.1\|804395_806801_+\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
NZ_CP040998.1\|WP_000758215.1\|790732_791257_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP040998.1\|WP_000660045.1\|793843_795049_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_CP040998.1\|WP_000167314.1\|799444_800635_-\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_CP040998.1\|WP_002871011.1\|795038_796418_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_CP040998.1\|WP_001067294.1\|802431_802809_-\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023
NZ_CP040998.1\|WP_000670752.1\|781783_782686_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP040998.1\|WP_000148849.1\|792161_793493_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CP040998.1\|WP_000185319.1\|796659_797589_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_CP040998.1\|WP_001081626.1\|806793_807222_+\|Na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000781156.1\|803881_804265_+\|kinase	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	1.89892e-52
NZ_CP040998.1\|WP_011443624.1\|807233_807563_+\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	3.20641e-61
NZ_CP040998.1\|WP_000035058.1\|803224_803818_-\|peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
NZ_CP040998.1\|WP_000838037.1\|800942_802070_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_CP040998.1\|WP_000138487.1\|798091_799336_-\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP040998.1\|WP_000154930.1\|782851_786505_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP040998.1\|WP_000711486.1\|790141_790717_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
NZ_CP040998.1\|WP_000007967.1\|791261_791837_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
NZ_CP040998.1\|WP_000172342.1\|786505_789982_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP040998.1\|WP_000573077.1\|807555_809052_+\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP040998.1\|WP_000054609.1\|804395_806801_+\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_CP040998.1\|WP_000758215.1\|790732_791257_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
NZ_CP040998.1\|WP_000660045.1\|793843_795049_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CP040998.1\|WP_000167314.1\|799444_800635_-\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_CP040998.1\|WP_002871011.1\|795038_796418_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP040998.1\|WP_001067294.1\|802431_802809_-\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
NZ_CP040998.1\|WP_000670752.1\|781783_782686_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
NZ_CP040998.1\|WP_000148849.1\|792161_793493_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP040998.1\|WP_000185319.1\|796659_797589_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
NZ_CP040998.1\|WP_001081626.1\|806793_807222_+\|Na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61

>NZ_CP040998.1|WP_000185319.1|796659_797589_+|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_CP040998.1|WP_002871011.1|795038_796418_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDNLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_CP040998.1|WP_000660045.1|793843_795049_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>NZ_CP040998.1|WP_000148849.1|792161_793493_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWIDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_CP040998.1|WP_000007967.1|791261_791837_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>NZ_CP040998.1|WP_000758215.1|790732_791257_-|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>NZ_CP040998.1|WP_000711486.1|790141_790717_-|signal-peptidase-I
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>NZ_CP040998.1|WP_000172342.1|786505_789982_-|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_CP040998.1|WP_000154930.1|782851_786505_-|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP040998.1|WP_000670752.1|781783_782686_-|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>NZ_CP040998.1|WP_000138487.1|798091_799336_-|Glu/Leu/Phe/Val-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_CP040998.1|WP_000167314.1|799444_800635_-|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_CP040998.1|WP_000838037.1|800942_802070_-|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_CP040998.1|WP_001067294.1|802431_802809_-|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_CP040998.1|WP_000035058.1|803224_803818_-|peptidyl-prolyl-cis-trans-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>NZ_CP040998.1|WP_000781156.1|803881_804265_+|kinase
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHDRKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>NZ_CP040998.1|WP_000054609.1|804395_806801_+|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>NZ_CP040998.1|WP_001081626.1|806793_807222_+|Na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>NZ_CP040998.1|WP_011443624.1|807233_807563_+|Na(+)/H(+)-antiporter-subunit-C
MIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>NZ_CP040998.1|WP_000573077.1|807555_809052_+|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP040998_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_3

890893-890974

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_3

>merge|NZ_CP040998|3|890893-890974|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_CP040998|3|2|890893-890974|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_001183858.1\|885226_886078_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP040998.1\|WP_000255561.1\|896598_897216_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP040998.1\|WP_000150017.1\|894264_894981_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP040998.1\|WP_000569884.1\|895949_896444_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP040998.1\|WP_000807671.1\|881376_882618_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP040998.1\|WP_001065801.1\|889660_889957_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP040998.1\|WP_000589549.1\|892672_893029_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP040998.1\|WP_000660172.1\|891957_892071_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000168845.1\|884137_884899_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP040998.1\|WP_000752917.1\|886310_886505_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP040998.1\|WP_000290485.1\|892134_892515_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP040998.1\|WP_000205572.1\|882732_884040_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP040998.1\|WP_000520233.1\|887697_888393_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP040998.1\|WP_001018962.1\|889949_890336_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP040998.1\|WP_000571218.1\|888385_889411_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP040998.1\|WP_000422908.1\|893642_894182_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP040998.1\|WP_001190695.1\|893172_893493_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP040998.1\|WP_000974460.1\|895128_895551_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP040998.1\|WP_000932216.1\|891077_891956_-\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP040998.1\|WP_000732326.1\|886858_887680_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_001183858.1\|885226_886078_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
NZ_CP040998.1\|WP_000255561.1\|896598_897216_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
NZ_CP040998.1\|WP_000150017.1\|894264_894981_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
NZ_CP040998.1\|WP_000569884.1\|895949_896444_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP040998.1\|WP_000807671.1\|881376_882618_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP040998.1\|WP_001065801.1\|889660_889957_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP040998.1\|WP_000589549.1\|892672_893029_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP040998.1\|WP_001190695.1\|893172_893493_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_CP040998.1\|WP_000168845.1\|884137_884899_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP040998.1\|WP_000752917.1\|886310_886505_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP040998.1\|WP_000290485.1\|892134_892515_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
NZ_CP040998.1\|WP_000205572.1\|882732_884040_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
NZ_CP040998.1\|WP_000520233.1\|887697_888393_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP040998.1\|WP_001018962.1\|889949_890336_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP040998.1\|WP_000571218.1\|888385_889411_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP040998.1\|WP_000422908.1\|893642_894182_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP040998.1\|WP_000974460.1\|895128_895551_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP040998.1\|WP_000932216.1\|891077_891956_-\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
NZ_CP040998.1\|WP_000732326.1\|886858_887680_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112

>NZ_CP040998.1|WP_001018962.1|889949_890336_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP040998.1|WP_001065801.1|889660_889957_-|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP040998.1|WP_000571218.1|888385_889411_-|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP040998.1|WP_000520233.1|887697_888393_-|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP040998.1|WP_000732326.1|886858_887680_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP040998.1|WP_000752917.1|886310_886505_-|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP040998.1|WP_001183858.1|885226_886078_+|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP040998.1|WP_000168845.1|884137_884899_-|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP040998.1|WP_000205572.1|882732_884040_-|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP040998.1|WP_000807671.1|881376_882618_-|cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF
>NZ_CP040998.1|WP_000932216.1|891077_891956_-|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP040998.1|WP_000660172.1|891957_892071_-|hypothetical-protein
MKEKLLGTIIWSIATFYYSRMMEIMNLAILKIKIGGS
>NZ_CP040998.1|WP_000290485.1|892134_892515_-|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_CP040998.1|WP_000589549.1|892672_893029_-|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP040998.1|WP_001190695.1|893172_893493_+|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP040998.1|WP_000422908.1|893642_894182_-|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP040998.1|WP_000150017.1|894264_894981_-|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>NZ_CP040998.1|WP_000974460.1|895128_895551_+|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP040998.1|WP_000569884.1|895949_896444_+|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP040998.1|WP_000255561.1|896598_897216_+|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP040998_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_4

934027-934112

Unclear

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_4

>merge|NZ_CP040998|4|934027-934112|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NZ_CP040998|4|3|934027-934112|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000638419.1\|944907_945144_-\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP040998.1\|WP_001049165.1\|929476_930064_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP040998.1\|WP_000958224.1\|938260_939193_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP040998.1\|WP_001836215.1\|937415_938255_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP040998.1\|WP_000134963.1\|934473_935409_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP040998.1\|WP_001074749.1\|922952_924143_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP040998.1\|WP_000070826.1\|926999_927629_-\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP040998.1\|WP_001790093.1\|946951_947059_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000369722.1\|932682_933594_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP040998.1\|WP_000654030.1\|925344_926358_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP040998.1\|WP_000816295.1\|928331_929234_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP040998.1\|WP_000749380.1\|945964_946804_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP040998.1\|WP_001248939.1\|931690_932686_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP040998.1\|WP_001260089.1\|922069_922831_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP040998.1\|WP_000279414.1\|924281_925292_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP040998.1\|WP_000662681.1\|939799_942646_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP040998.1\|WP_000006551.1\|930636_931581_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP040998.1\|WP_000057542.1\|935475_936915_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP040998.1\|WP_001224793.1\|936922_937408_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP040998.1\|WP_000229253.1\|942653_944639_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000638419.1\|944907_945144_-\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP040998.1\|WP_001049165.1\|929476_930064_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP040998.1\|WP_000958224.1\|938260_939193_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP040998.1\|WP_001836215.1\|937415_938255_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	9.1614e-120
NZ_CP040998.1\|WP_000134963.1\|934473_935409_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP040998.1\|WP_001074749.1\|922952_924143_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP040998.1\|WP_000070826.1\|926999_927629_-\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
NZ_CP040998.1\|WP_000369722.1\|932682_933594_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP040998.1\|WP_000654030.1\|925344_926358_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP040998.1\|WP_000816295.1\|928331_929234_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NZ_CP040998.1\|WP_000749380.1\|945964_946804_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NZ_CP040998.1\|WP_001248939.1\|931690_932686_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP040998.1\|WP_001260089.1\|922069_922831_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NZ_CP040998.1\|WP_000279414.1\|924281_925292_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP040998.1\|WP_000662681.1\|939799_942646_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP040998.1\|WP_000006551.1\|930636_931581_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP040998.1\|WP_000057542.1\|935475_936915_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	3.57983e-06
NZ_CP040998.1\|WP_001224793.1\|936922_937408_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP040998.1\|WP_000229253.1\|942653_944639_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0

>NZ_CP040998.1|WP_000369722.1|932682_933594_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP040998.1|WP_001248939.1|931690_932686_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP040998.1|WP_000006551.1|930636_931581_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP040998.1|WP_001049165.1|929476_930064_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP040998.1|WP_000816295.1|928331_929234_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP040998.1|WP_000070826.1|926999_927629_-|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP040998.1|WP_000654030.1|925344_926358_-|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP040998.1|WP_000279414.1|924281_925292_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP040998.1|WP_001074749.1|922952_924143_-|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP040998.1|WP_001260089.1|922069_922831_-|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
>NZ_CP040998.1|WP_000134963.1|934473_935409_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP040998.1|WP_000057542.1|935475_936915_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP040998.1|WP_001224793.1|936922_937408_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP040998.1|WP_001836215.1|937415_938255_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGSLPWPTKKVK
>NZ_CP040998.1|WP_000958224.1|938260_939193_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP040998.1|WP_000662681.1|939799_942646_-|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP040998.1|WP_000229253.1|942653_944639_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP040998.1|WP_000638419.1|944907_945144_-|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP040998.1|WP_000749380.1|945964_946804_-|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP040998.1|WP_001790093.1|946951_947059_-|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIIENVLNYMV

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Crispr_ID: NZ_CP040998_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_5

939430-939510

Unclear

Consensus_repeat	Method
AGTTGGCGGGGCCCCAACATAAAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_5

>merge|NZ_CP040998|5|939430-939510|CRISPRCasFinder
AGTTGGCGGGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGCGGGGCCCCAACATAAAGAA

>NZ_CP040998|5|4|939430-939510|CRISPRCasFinder
AGTTGGCGGGGCCCCAACATAAAGAA	TTTCGAAAAGAAATTCTACAAACAATGCA
AGTTGGCGGGGCCCCAACATAAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000638419.1\|944907_945144_-\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP040998.1\|WP_001049165.1\|929476_930064_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP040998.1\|WP_000958224.1\|938260_939193_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP040998.1\|WP_001836215.1\|937415_938255_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP040998.1\|WP_000134963.1\|934473_935409_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP040998.1\|WP_010956549.1\|947212_948323_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP040998.1\|WP_000506531.1\|948637_951169_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP040998.1\|WP_000617735.1\|951582_952155_-\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP040998.1\|WP_001790093.1\|946951_947059_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000369722.1\|932682_933594_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP040998.1\|WP_000662681.1\|939799_942646_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP040998.1\|WP_000816295.1\|928331_929234_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP040998.1\|WP_000749380.1\|945964_946804_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP040998.1\|WP_001248939.1\|931690_932686_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP040998.1\|WP_000229253.1\|942653_944639_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP040998.1\|WP_001790092.1\|948491_948596_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000006551.1\|930636_931581_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP040998.1\|WP_000057542.1\|935475_936915_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP040998.1\|WP_001224793.1\|936922_937408_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP040998.1\|WP_001057965.1\|952215_952890_-\|ComF-family-protein	unknown	unknown	gnl\|CDD\|223970

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000638419.1\|944907_945144_-\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP040998.1\|WP_001049165.1\|929476_930064_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP040998.1\|WP_000958224.1\|938260_939193_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP040998.1\|WP_001836215.1\|937415_938255_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	9.1614e-120
NZ_CP040998.1\|WP_000134963.1\|934473_935409_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP040998.1\|WP_010956549.1\|947212_948323_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP040998.1\|WP_000617735.1\|951582_952155_-\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP040998.1\|WP_000369722.1\|932682_933594_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP040998.1\|WP_000662681.1\|939799_942646_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP040998.1\|WP_000816295.1\|928331_929234_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NZ_CP040998.1\|WP_000749380.1\|945964_946804_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NZ_CP040998.1\|WP_001248939.1\|931690_932686_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP040998.1\|WP_000229253.1\|942653_944639_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP040998.1\|WP_000506531.1\|948637_951169_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP040998.1\|WP_000006551.1\|930636_931581_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP040998.1\|WP_000057542.1\|935475_936915_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	3.57983e-06
NZ_CP040998.1\|WP_001224793.1\|936922_937408_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP040998.1\|WP_001057965.1\|952215_952890_-\|ComF-family-protein	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.0058e-51

>NZ_CP040998.1|WP_000958224.1|938260_939193_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP040998.1|WP_001836215.1|937415_938255_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGSLPWPTKKVK
>NZ_CP040998.1|WP_001224793.1|936922_937408_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP040998.1|WP_000057542.1|935475_936915_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP040998.1|WP_000134963.1|934473_935409_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP040998.1|WP_000369722.1|932682_933594_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP040998.1|WP_001248939.1|931690_932686_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP040998.1|WP_000006551.1|930636_931581_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP040998.1|WP_001049165.1|929476_930064_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP040998.1|WP_000816295.1|928331_929234_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP040998.1|WP_000662681.1|939799_942646_-|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP040998.1|WP_000229253.1|942653_944639_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP040998.1|WP_000638419.1|944907_945144_-|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP040998.1|WP_000749380.1|945964_946804_-|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP040998.1|WP_001790093.1|946951_947059_-|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIIENVLNYMV
>NZ_CP040998.1|WP_010956549.1|947212_948323_-|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP040998.1|WP_001790092.1|948491_948596_-|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP040998.1|WP_000506531.1|948637_951169_-|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP040998.1|WP_000617735.1|951582_952155_-|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_CP040998.1|WP_001057965.1|952215_952890_-|ComF-family-protein
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR

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Crispr_ID: NZ_CP040998_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_6

1033364-1033462

Orphan

Consensus_repeat	Method
CCCCTTTTAATTTATTAATTAGGGGCTCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_6

>merge|NZ_CP040998|6|1033364-1033462|CRISPRCasFinder
CCCCTTTTAATTTATTAATTAGGGGCTCTTATGCAGTTGGTGCATTAGCAACCAACTGTATTCCTTTGTCCCCTTTTAATTTATTAATTAGGGGCTCTT

>NZ_CP040998|6|5|1033364-1033462|CRISPRCasFinder
CCCCTTTTAATTTATTAATTAGGGGCTCTT	ATGCAGTTGGTGCATTAGCAACCAACTGTATTCCTTTGT
CCCCTTTTAATTTATTAATTAGGGGCTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000820892.1\|1028099_1028666_+\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_CP040998.1\|WP_001259678.1\|1030282_1030726_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP040998.1\|WP_000152582.1\|1031640_1032129_-\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_CP040998.1\|WP_001129754.1\|1037409_1039560_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP040998.1\|WP_000081602.1\|1040256_1040901_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223742
NZ_CP040998.1\|WP_000148828.1\|1027639_1028098_+\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_CP040998.1\|WP_001789973.1\|1035317_1035434_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000833483.1\|1035525_1035999_-\|cupin	unknown	unknown	gnl\|CDD\|226072
NZ_CP040998.1\|WP_000842860.1\|1030852_1031542_+\|DUF1129-family-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000358498.1\|1026953_1027637_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP040998.1\|WP_001090985.1\|1036904_1037264_-\|HTH-type-transcriptional-regulator-SarX	unknown	unknown	gnl\|CDD\|130944
NZ_CP040998.1\|WP_000638613.1\|1028761_1029304_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP040998.1\|WP_000120368.1\|1042646_1043654_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NZ_CP040998.1\|WP_000545115.1\|1029383_1029683_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000367064.1\|1032125_1033346_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341024
NZ_CP040998.1\|WP_000733431.1\|1029820_1030216_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240271
NZ_CP040998.1\|WP_000532966.1\|1035998_1036715_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_CP040998.1\|WP_000865624.1\|1034528_1035173_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
NZ_CP040998.1\|WP_000731644.1\|1041261_1042059_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP040998.1\|WP_000687411.1\|1033546_1034413_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000820892.1\|1028099_1028666_+\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.24037e-61
NZ_CP040998.1\|WP_001259678.1\|1030282_1030726_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.56694e-12
NZ_CP040998.1\|WP_000152582.1\|1031640_1032129_-\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	4.76789e-44
NZ_CP040998.1\|WP_001129754.1\|1037409_1039560_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.1737e-20
NZ_CP040998.1\|WP_000081602.1\|1040256_1040901_-\|hypothetical-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	1.16188e-32
NZ_CP040998.1\|WP_000148828.1\|1027639_1028098_+\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	1.18273e-77
NZ_CP040998.1\|WP_000833483.1\|1035525_1035999_-\|cupin	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	1.99109e-74
NZ_CP040998.1\|WP_000532966.1\|1035998_1036715_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
NZ_CP040998.1\|WP_000358498.1\|1026953_1027637_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000491798
NZ_CP040998.1\|WP_001090985.1\|1036904_1037264_-\|HTH-type-transcriptional-regulator-SarX	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.54609e-22
NZ_CP040998.1\|WP_000638613.1\|1028761_1029304_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.77698e-28
NZ_CP040998.1\|WP_000120368.1\|1042646_1043654_-\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	5.23541e-104
NZ_CP040998.1\|WP_000367064.1\|1032125_1033346_-\|MFS-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.37741e-101
NZ_CP040998.1\|WP_000733431.1\|1029820_1030216_-\|hypothetical-protein	gnl\|CDD\|240271	PTZ00108, PTZ00108, DNA topoisomerase 2-like protein; Provisional.	0.00179936
NZ_CP040998.1\|WP_000865624.1\|1034528_1035173_-\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	1.46792e-91
NZ_CP040998.1\|WP_000731644.1\|1041261_1042059_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.27934e-40
NZ_CP040998.1\|WP_000687411.1\|1033546_1034413_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.51151e-39

>NZ_CP040998.1|WP_000367064.1|1032125_1033346_-|MFS-transporter
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>NZ_CP040998.1|WP_000152582.1|1031640_1032129_-|DUF456-domain-containing-protein
MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>NZ_CP040998.1|WP_000842860.1|1030852_1031542_+|DUF1129-family-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKNGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>NZ_CP040998.1|WP_001259678.1|1030282_1030726_-|GNAT-family-N-acetyltransferase
MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISNTIHKNNLPMISLNKDLGYQVSHVKMYKDID
>NZ_CP040998.1|WP_000733431.1|1029820_1030216_-|hypothetical-protein
MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKDKEASQDKQSKDQTKSSDKDNHKKPTSADKDQKANDKHQS
>NZ_CP040998.1|WP_000545115.1|1029383_1029683_-|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGHTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>NZ_CP040998.1|WP_000638613.1|1028761_1029304_-|GNAT-family-N-acetyltransferase
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKATLKLAEEHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>NZ_CP040998.1|WP_000820892.1|1028099_1028666_+|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>NZ_CP040998.1|WP_000148828.1|1027639_1028098_+|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
>NZ_CP040998.1|WP_000358498.1|1026953_1027637_+|hypothetical-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKEEQKAREKNEIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA
>NZ_CP040998.1|WP_000687411.1|1033546_1034413_-|LysR-family-transcriptional-regulator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>NZ_CP040998.1|WP_000865624.1|1034528_1035173_-|DUF402-domain-containing-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNHQKPQNKTNIEKSKQIKPKQYNQTKNHQQQKKN
>NZ_CP040998.1|WP_001789973.1|1035317_1035434_-|hypothetical-protein
MLQLFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN
>NZ_CP040998.1|WP_000833483.1|1035525_1035999_-|cupin
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPKGTIFASSIEISNTFSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>NZ_CP040998.1|WP_000532966.1|1035998_1036715_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>NZ_CP040998.1|WP_001090985.1|1036904_1037264_-|HTH-type-transcriptional-regulator-SarX
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
>NZ_CP040998.1|WP_001129754.1|1037409_1039560_-|helix-turn-helix-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>NZ_CP040998.1|WP_000081602.1|1040256_1040901_-|hypothetical-protein
MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>NZ_CP040998.1|WP_000731644.1|1041261_1042059_+|LysM-peptidoglycan-binding-domain-containing-protein
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>NZ_CP040998.1|WP_000120368.1|1042646_1043654_-|inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLAGLLFYILNLFF

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Crispr_ID: NZ_CP040998_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_7

1096355-1096447

Orphan

Consensus_repeat	Method
TAGCATCCAACTGCGTTCCTCTTCATCTTTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_7

>merge|NZ_CP040998|7|1096355-1096447|CRISPRCasFinder
TAGCATCCAACTGCGTTCCTCTTCATCTTTAGCGATTAGAGGCTTTTATGCAGTTGTGCCTTAGCATCCAACTGCGTTCCTCTTCACCTTTAG

>NZ_CP040998|7|6|1096355-1096447|CRISPRCasFinder
TAGCATCCAACTGCGTTCCTCTTCATCTTTAG	CGATTAGAGGCTTTTATGCAGTTGTGCCT
TAGCATCCAACTGCGTTCCTCTTCACCTTTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_001018677.1\|1089640_1090015_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP040998.1\|WP_000735558.1\|1092100_1092607_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000901764.1\|1096664_1097300_-\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP040998.1\|WP_000365354.1\|1093526_1094246_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP040998.1\|WP_001788287.1\|1101546_1102068_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP040998.1\|WP_001045421.1\|1090265_1091054_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP040998.1\|WP_000362967.1\|1092742_1093543_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP040998.1\|WP_001813976.1\|1095398_1096226_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP040998.1\|WP_000169042.1\|1087344_1087569_+\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP040998.1\|WP_000180230.1\|1102095_1103391_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP040998.1\|WP_000655099.1\|1099855_1099963_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000808902.1\|1104822_1105761_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP040998.1\|WP_001790232.1\|1094300_1095251_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP040998.1\|WP_001021145.1\|1097688_1099350_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP040998.1\|WP_001819741.1\|1099346_1099730_-\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP040998.1\|WP_000477504.1\|1103430_1103907_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP040998.1\|WP_001222133.1\|1091222_1091939_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000633782.1\|1104075_1104612_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP040998.1\|WP_001553862.1\|1087763_1088693_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP040998.1\|WP_001200748.1\|1100037_1101048_-\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_001018677.1\|1089640_1090015_+\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP040998.1\|WP_001200748.1\|1100037_1101048_-\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP040998.1\|WP_000901764.1\|1096664_1097300_-\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_CP040998.1\|WP_000365354.1\|1093526_1094246_-\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP040998.1\|WP_001788287.1\|1101546_1102068_-\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP040998.1\|WP_001045421.1\|1090265_1091054_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
NZ_CP040998.1\|WP_001813976.1\|1095398_1096226_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.32108e-72
NZ_CP040998.1\|WP_000169042.1\|1087344_1087569_+\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NZ_CP040998.1\|WP_000180230.1\|1102095_1103391_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP040998.1\|WP_000808902.1\|1104822_1105761_-\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_CP040998.1\|WP_001790232.1\|1094300_1095251_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_CP040998.1\|WP_001021145.1\|1097688_1099350_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP040998.1\|WP_001819741.1\|1099346_1099730_-\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
NZ_CP040998.1\|WP_000477504.1\|1103430_1103907_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP040998.1\|WP_000362967.1\|1092742_1093543_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
NZ_CP040998.1\|WP_000633782.1\|1104075_1104612_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NZ_CP040998.1\|WP_001553862.1\|1087763_1088693_+\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37

>NZ_CP040998.1|WP_001813976.1|1095398_1096226_-|ABC-transporter-substrate-binding-protein
MKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP040998.1|WP_001790232.1|1094300_1095251_-|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP040998.1|WP_000365354.1|1093526_1094246_-|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP040998.1|WP_000362967.1|1092742_1093543_-|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP040998.1|WP_000735558.1|1092100_1092607_-|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP040998.1|WP_001222133.1|1091222_1091939_-|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP040998.1|WP_001045421.1|1090265_1091054_-|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NZ_CP040998.1|WP_001018677.1|1089640_1090015_+|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP040998.1|WP_001553862.1|1087763_1088693_+|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP040998.1|WP_000169042.1|1087344_1087569_+|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK
>NZ_CP040998.1|WP_000901764.1|1096664_1097300_-|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP040998.1|WP_001021145.1|1097688_1099350_-|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP040998.1|WP_001819741.1|1099346_1099730_-|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP040998.1|WP_000655099.1|1099855_1099963_-|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NZ_CP040998.1|WP_001200748.1|1100037_1101048_-|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP040998.1|WP_001788287.1|1101546_1102068_-|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP040998.1|WP_000180230.1|1102095_1103391_-|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP040998.1|WP_000477504.1|1103430_1103907_-|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP040998.1|WP_000633782.1|1104075_1104612_-|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP040998.1|WP_000808902.1|1104822_1105761_-|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED

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Crispr_ID: NZ_CP040998_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_8

1341251-1341352

Orphan

Consensus_repeat	Method
CAAATTTAATACTCAATTCATATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_8

>merge|NZ_CP040998|8|1341251-1341352|CRISPRCasFinder
CAAATTTAATACTCAATTCATATATAGCTTTGATTTAAAAACTGATTTTTATAAACCTATAGAACTGTAATTTACTTTCAAATTTAATACTCAATTCATAAA

>NZ_CP040998|8|7|1341251-1341352|CRISPRCasFinder
CAAATTTAATACTCAATTCATATA	TAGCTTTGATTTAAAAACTGATTTTTATAAACCTATAGAACTGTAATTTACTTT
CAAATTTAATACTCAATTCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000956132.1\|1340277_1341234_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_CP040998.1\|WP_000211676.1\|1349568_1349778_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000746687.1\|1347479_1348106_+\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP040998.1\|WP_000551776.1\|1332869_1333406_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000052781.1\|1344926_1345496_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP040998.1\|WP_000793009.1\|1336588_1337857_-\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP040998.1\|WP_000930486.1\|1345511_1347035_+\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP040998.1\|WP_000264071.1\|1335084_1336551_-\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP040998.1\|WP_000041883.1\|1331772_1332477_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP040998.1\|WP_000159787.1\|1331101_1331374_+\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP040998.1\|WP_000991007.1\|1342210_1343599_+\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP040998.1\|WP_001795623.1\|1347113_1347407_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000394698.1\|1339497_1340160_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000868248.1\|1348360_1348744_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000763768.1\|1338947_1339355_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP040998.1\|WP_000424966.1\|1333518_1335060_-\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP040998.1\|WP_001789518.1\|1342024_1342126_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_001289311.1\|1343679_1344435_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP040998.1\|WP_000158374.1\|1348809_1349391_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP040998.1\|WP_000421410.1\|1337856_1338435_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000956132.1\|1340277_1341234_+\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
NZ_CP040998.1\|WP_000746687.1\|1347479_1348106_+\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
NZ_CP040998.1\|WP_000052781.1\|1344926_1345496_+\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NZ_CP040998.1\|WP_000158374.1\|1348809_1349391_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
NZ_CP040998.1\|WP_000793009.1\|1336588_1337857_-\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
NZ_CP040998.1\|WP_000930486.1\|1345511_1347035_+\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP040998.1\|WP_000264071.1\|1335084_1336551_-\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP040998.1\|WP_000041883.1\|1331772_1332477_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
NZ_CP040998.1\|WP_000159787.1\|1331101_1331374_+\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NZ_CP040998.1\|WP_000991007.1\|1342210_1343599_+\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP040998.1\|WP_001289311.1\|1343679_1344435_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
NZ_CP040998.1\|WP_000763768.1\|1338947_1339355_+\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
NZ_CP040998.1\|WP_000424966.1\|1333518_1335060_-\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP040998.1\|WP_000421410.1\|1337856_1338435_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119

>NZ_CP040998.1|WP_000956132.1|1340277_1341234_+|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP040998.1|WP_000394698.1|1339497_1340160_+|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP040998.1|WP_000763768.1|1338947_1339355_+|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>NZ_CP040998.1|WP_000421410.1|1337856_1338435_-|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_CP040998.1|WP_000793009.1|1336588_1337857_-|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP040998.1|WP_000264071.1|1335084_1336551_-|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP040998.1|WP_000424966.1|1333518_1335060_-|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP040998.1|WP_000551776.1|1332869_1333406_+|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NZ_CP040998.1|WP_000041883.1|1331772_1332477_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NZ_CP040998.1|WP_000159787.1|1331101_1331374_+|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI
>NZ_CP040998.1|WP_001789518.1|1342024_1342126_-|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>NZ_CP040998.1|WP_000991007.1|1342210_1343599_+|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>NZ_CP040998.1|WP_001289311.1|1343679_1344435_-|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP040998.1|WP_000052781.1|1344926_1345496_+|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP040998.1|WP_000930486.1|1345511_1347035_+|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP040998.1|WP_001795623.1|1347113_1347407_+|hypothetical-protein
MINLIYTTRCAIMLKVCTSRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLVQPIMQLFIDKAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>NZ_CP040998.1|WP_000746687.1|1347479_1348106_+|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP040998.1|WP_000868248.1|1348360_1348744_+|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>NZ_CP040998.1|WP_000158374.1|1348809_1349391_-|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>NZ_CP040998.1|WP_000211676.1|1349568_1349778_+|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFNPILSTFSNIIIHIDHFHANKKDDN

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Crispr_ID: NZ_CP040998_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_9

1762877-1763050

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAG	PILER-CR
TTACAATAATGTGCAAGTTGGCGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP040998_9

>merge|NZ_CP040998|9|1762877-1763050|PILER-CR,CRISPRCasFinder
TTGGCGAGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGCGGGGCCCCAACAAAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGGTTACAATAATGTGCAAGTTGGGGT

>NZ_CP040998|9|1|1762877-1763021|PILER-CR
TTGGCGAGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCA	AGTTGGCGGGGCCCCAA
CAAAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCC	CAACATAGAAGCTGGC
GGAAAG

>NZ_CP040998|9|8|1762971-1763050|CRISPRCasFinder
TTACAATAATGTGCAAGTTGGCGG	GGCCCCAACATAGAAGCTGGCGGAAAGTCAGG
TTACAATAATGTGCAAGTTGGGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000244278.1\|1770583_1771084_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP040998.1\|WP_000571736.1\|1757555_1758260_+\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	unknown	unknown	gnl\|CDD\|172156
NZ_CP040998.1\|WP_025175201.1\|1759836_1760016_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000592609.1\|1758256_1759015_+\|imidazole-glycerol-phosphate-synthase-subunit-HisF	unknown	unknown	gnl\|CDD\|234996
NZ_CP040998.1\|WP_000565310.1\|1769581_1770349_+\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP040998.1\|WP_000640266.1\|1756409_1756988_+\|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl\|CDD\|153419
NZ_CP040998.1\|WP_000723836.1\|1763225_1764278_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226446
NZ_CP040998.1\|WP_000635623.1\|1756984_1757563_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|171871
NZ_CP040998.1\|WP_000930643.1\|1754161_1755412_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|172308
NZ_CP040998.1\|WP_000170492.1\|1759011_1759644_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	unknown	unknown	gnl\|CDD\|235067
NZ_CP040998.1\|WP_000944149.1\|1753554_1754169_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|172153
NZ_CP040998.1\|WP_000240580.1\|1765133_1765439_-\|intracellular-adhesion-protein-D	unknown	unknown	gnl\|CDD\|188447
NZ_CP040998.1\|WP_001159430.1\|1765402_1766641_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|274866
NZ_CP040998.1\|WP_000842036.1\|1760736_1762779_+\|YSIRK-domain-containing-triacylglycerol-lipase-Lip1	unknown	unknown	gnl\|CDD\|224001
NZ_CP040998.1\|WP_000185864.1\|1768892_1769585_+\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP040998.1\|WP_000301926.1\|1771086_1771563_+\|peptide-methionine-(S)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|235497
NZ_CP040998.1\|WP_000877317.1\|1764264_1765137_-\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	unknown	unknown	gnl\|CDD\|188448
NZ_CP040998.1\|WP_000653261.1\|1766804_1767365_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376089
NZ_CP040998.1\|WP_000659675.1\|1768213_1768876_+\|capsular-polysaccharide-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|226453
NZ_CP040998.1\|WP_000639183.1\|1755427_1756441_+\|histidinol-phosphate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223157

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000244278.1\|1770583_1771084_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.30563e-13
NZ_CP040998.1\|WP_000571736.1\|1757555_1758260_+\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	gnl\|CDD\|172156	PRK13587, PRK13587, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Provisional.	2.24553e-168
NZ_CP040998.1\|WP_000592609.1\|1758256_1759015_+\|imidazole-glycerol-phosphate-synthase-subunit-HisF	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	5.46363e-153
NZ_CP040998.1\|WP_000565310.1\|1769581_1770349_+\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.38228e-144
NZ_CP040998.1\|WP_000640266.1\|1756409_1756988_+\|imidazoleglycerol-phosphate-dehydratase-HisB	gnl\|CDD\|153419	cd07914, IGPD, Imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase (IGPD; EC 4.2.1.19) catalyzes the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, the sixth step of histidine biosynthesis in plants and microorganisms where the histidine is synthesized de novo. There is an internal repeat in the protein domain that is related by pseudo-dyad symmetry, perhaps as a result of an ancient gene duplication. The apo-form of IGPD exists as a catalytically inactive trimer which, in the presence of specific divalent metal cations such as manganese (Mn2+), cobalt (Co2+), cadmium (Cd2+), nickel (Ni2+), iron (Fe2+) and zinc (Zn2+), assembles to form a biologically active high molecular weight metalloenzyme; a 24-mer with 4-3-2 symmetry. Each 24-mer has 24 active sites, and contains around 1.5 metal ions per monomer, each monomer contributing residues to three separate active sites. IGPD enzymes are monofunctional in fungi, plants, archaea and some eubacteria while they are encoded as bifunctional enzymes in other eubacteria, such that the enzyme is fused to histidinol-phosphate phosphatase, the penultimate enzyme of the histidine biosynthesis pathway. The histidine biosynthesis pathway is a potential target for development of herbicides, and IGPD is a target for the triazole phosphonate herbicides.	2.40504e-103
NZ_CP040998.1\|WP_000723836.1\|1763225_1764278_-\|acyltransferase-family-protein	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	5.4483e-115
NZ_CP040998.1\|WP_000635623.1\|1756984_1757563_+\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|171871	PRK13142, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	1.76981e-127
NZ_CP040998.1\|WP_000930643.1\|1754161_1755412_+\|histidinol-dehydrogenase	gnl\|CDD\|172308	PRK13770, PRK13770, histidinol dehydrogenase; Provisional.	0
NZ_CP040998.1\|WP_000170492.1\|1759011_1759644_+\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	1.98613e-110
NZ_CP040998.1\|WP_000944149.1\|1753554_1754169_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|172153	PRK13584, hisG, ATP phosphoribosyltransferase.	2.32782e-134
NZ_CP040998.1\|WP_000240580.1\|1765133_1765439_-\|intracellular-adhesion-protein-D	gnl\|CDD\|188447	TIGR03932, IcaD_partial, intracellular adhesion protein D. Members of this protein family are IcaD (intracellular adhesion protein D), which with catalytic subunit IcaA forms an N-acetylglucosaminyltransferase. In the absence of IcaC, this enzyme forms N-acetylglucosamine oligomers up to 20 in length. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.14464e-30
NZ_CP040998.1\|WP_001159430.1\|1765402_1766641_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|274866	TIGR03937, Poly-beta-16-N-acetyl-D-glucosamine_synthase, poly-beta-1,6 N-acetyl-D-glucosamine synthase. Members of this protein family are biofilm-forming enzymes that polymerize N-acetyl-D-glucosamine residues in beta(1,6) linkage. One named members is IcaA (intercellular adhesin protein A), an enzyme that acts (with aid of subunit IcaD) in Polysaccharide Intercellular Adhesin (PIA) biosynthesis in Staphylococcus epidermis). The homologous member in E. coli is designated PgaC. Members are often encoded next to a polysaccharide deacetylase and involved in biofilm formation. Note that chitin, although also made from N-acetylglucosamine, is formed with beta-1,4 linkages.	0
NZ_CP040998.1\|WP_000842036.1\|1760736_1762779_+\|YSIRK-domain-containing-triacylglycerol-lipase-Lip1	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	1.58472e-82
NZ_CP040998.1\|WP_000185864.1\|1768892_1769585_+\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.92039e-84
NZ_CP040998.1\|WP_000301926.1\|1771086_1771563_+\|peptide-methionine-(S)-S-oxide-reductase	gnl\|CDD\|235497	PRK05528, PRK05528, peptide-methionine (S)-S-oxide reductase.	1.4924e-106
NZ_CP040998.1\|WP_000877317.1\|1764264_1765137_-\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	gnl\|CDD\|188448	TIGR03933, Poly-beta-16-N-acetyl-D-glucosamine_N-deacetylase, intercellular adhesin biosynthesis polysaccharide N-deacetylase. A common motif in bacterial biosynthesis of polysaccharide for export is modification that follows polymerization. This model describes a subfamily of polysaccharide N-deacetylases that acts on poly-beta-1,6-N-acetyl-D-glyscosamine as produced by Staphylococcus epidermidis and S. aureus. The end product in these species is designated polysaccharide intercellular adhesin (PIA), and this gene designated icaB (intercellular adhesion protein B). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Cellular processes, Pathogenesis].	1.47819e-150
NZ_CP040998.1\|WP_000653261.1\|1766804_1767365_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|376089	pfam18665, TetR_C_37, Tetracyclin repressor-like, C-terminal domain. IcaR belongs to the tetracycline repressor (TetR) family of proteins, which are involved in a wide variety of gene regulations. It binds to a 42 bp region immediately upstream of the icaA gene. This entry represents the C-terminal domain which is involved in dimerization.	2.88245e-28
NZ_CP040998.1\|WP_000659675.1\|1768213_1768876_+\|capsular-polysaccharide-biosynthesis-protein-CapA	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	5.65863e-89
NZ_CP040998.1\|WP_000639183.1\|1755427_1756441_+\|histidinol-phosphate-aminotransferase-family-protein	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	5.6943e-85

>NZ_CP040998.1|WP_000842036.1|1760736_1762779_+|YSIRK-domain-containing-triacylglycerol-lipase-Lip1
MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKKSSLNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEADNSQDSNANNNLPSQSRIKEAPSLNKLDQTSQREIVNETEIEKVQPQQNNQANDKITNYNFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNHDNMISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTKATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKLTDTKQA
>NZ_CP040998.1|WP_025175201.1|1759836_1760016_+|hypothetical-protein
MKSKLSNSGIDVTVKDVEKYMNRYNEVMKGKNGEKAKELCLSLLPINIIVVFTFFVFIL
>NZ_CP040998.1|WP_000170492.1|1759011_1759644_+|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE
MTKYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGVVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
>NZ_CP040998.1|WP_000592609.1|1758256_1759015_+|imidazole-glycerol-phosphate-synthase-subunit-HisF
MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTTGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
>NZ_CP040998.1|WP_000571736.1|1757555_1758260_+|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase
MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
>NZ_CP040998.1|WP_000635623.1|1756984_1757563_+|imidazole-glycerol-phosphate-synthase-subunit-HisH
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNTSKIIDQAETIILPGVGHFKDAMSEIKRLNLNAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGADIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND
>NZ_CP040998.1|WP_000640266.1|1756409_1756988_+|imidazoleglycerol-phosphate-dehydratase-HisB
MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
>NZ_CP040998.1|WP_000639183.1|1755427_1756441_+|histidinol-phosphate-aminotransferase-family-protein
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRQFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS
>NZ_CP040998.1|WP_000930643.1|1754161_1755412_+|histidinol-dehydrogenase
MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYNLTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEESVECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSQEVLAACYITQVDQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGIDQIAGPTEIALIIDETADLDAIVYDVFAQAEHDELARTYAISEDAQVLKDLESRIAKALPNVDRYDIVSKSIANQHYLIHASNFDEACHVMNTIAPEHASIQTVNPQPYIEKVKYVGALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFEQIADSAQHIAHVEALYNHQQSILIRQS
>NZ_CP040998.1|WP_000944149.1|1753554_1754169_+|ATP-phosphoribosyltransferase
MLRIAIAKGRLMDSLINYLDVIEYTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPETTNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA
>NZ_CP040998.1|WP_000723836.1|1763225_1764278_-|acyltransferase-family-protein
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
>NZ_CP040998.1|WP_000877317.1|1764264_1765137_-|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase
MKYRKFIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
>NZ_CP040998.1|WP_000240580.1|1765133_1765439_-|intracellular-adhesion-protein-D
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
>NZ_CP040998.1|WP_001159430.1|1765402_1766641_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
>NZ_CP040998.1|WP_000653261.1|1766804_1767365_+|TetR/AcrR-family-transcriptional-regulator
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
>NZ_CP040998.1|WP_000659675.1|1768213_1768876_+|capsular-polysaccharide-biosynthesis-protein-CapA
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
>NZ_CP040998.1|WP_000185864.1|1768892_1769585_+|polysaccharide-biosynthesis-tyrosine-autokinase
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVVNSENNNRDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
>NZ_CP040998.1|WP_000565310.1|1769581_1770349_+|tyrosine-protein-phosphatase
MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILKGLDNGSIQGINRSKYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYSNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF
>NZ_CP040998.1|WP_000244278.1|1770583_1771084_+|GNAT-family-N-acetyltransferase
MVLRKVIMQDLDQIIALENIGFSPEEAATREALKLRIEQIQETFIVAEKNDEVIGYINGPVIKERYISDDLFKNVSTNNSEGGYISVLGLVVAPNYQGQGIAGRLLNYFETLAKNHHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNIKKDDEV
>NZ_CP040998.1|WP_000301926.1|1771086_1771563_+|peptide-methionine-(S)-S-oxide-reductase
MAVVYVAGGCLWGVEAFFATIPGIIHTEAGRANGRSSKLDGPYDGYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNQQGNDIGQKYRTGLYSCVDDHLIEARQFIERRKDRDQIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISKDLLNKYK

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Crispr_ID: NZ_CP040998_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_10

2205161-2205251

Orphan

Consensus_repeat	Method
AAAAGAAATTCTACAGACAATGCAAGTTGGGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_10

>merge|NZ_CP040998|10|2205161-2205251|CRISPRCasFinder
AAAAGAAATTCTACAGACAATGCAAGTTGGGGAACGGGGCCCCAACATAGAGAATTTCAAAAGAAATTCTACAGACAATGCAAGTTGGGGA

>NZ_CP040998|10|9|2205161-2205251|CRISPRCasFinder
AAAAGAAATTCTACAGACAATGCAAGTTGGGGA	ACGGGGCCCCAACATAGAGAATTTC
AAAAGAAATTCTACAGACAATGCAAGTTGGGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000066900.1\|2205562_2205913_+\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP040998.1\|WP_000413865.1\|2209218_2210484_+\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP040998.1\|WP_001790034.1\|2205266_2205437_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000076929.1\|2198739_2199744_+\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP040998.1\|WP_000600967.1\|2207822_2208587_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP040998.1\|WP_000866971.1\|2203046_2203280_+\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP040998.1\|WP_001549681.1\|2208578_2208830_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_001161085.1\|2213954_2214272_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000808500.1\|2202594_2203041_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP040998.1\|WP_000592303.1\|2210600_2213768_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP040998.1\|WP_000184419.1\|2206016_2207228_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP040998.1\|WP_000913019.1\|2197964_2198570_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP040998.1\|WP_000259718.1\|2200839_2202099_+\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP040998.1\|WP_000643988.1\|2203286_2203886_+\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP040998.1\|WP_000602937.1\|2202095_2202581_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP040998.1\|WP_000051206.1\|2214516_2214681_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000230173.1\|2203905_2204928_+\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP040998.1\|WP_000951058.1\|2207220_2207661_-\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP040998.1\|WP_000134528.1\|2200282_2200777_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP040998.1\|WP_000503820.1\|2199774_2200281_+\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000066900.1\|2205562_2205913_+\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP040998.1\|WP_000413865.1\|2209218_2210484_+\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NZ_CP040998.1\|WP_000076929.1\|2198739_2199744_+\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NZ_CP040998.1\|WP_000600967.1\|2207822_2208587_+\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP040998.1\|WP_000866971.1\|2203046_2203280_+\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP040998.1\|WP_000808500.1\|2202594_2203041_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP040998.1\|WP_000592303.1\|2210600_2213768_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP040998.1\|WP_000184419.1\|2206016_2207228_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
NZ_CP040998.1\|WP_000913019.1\|2197964_2198570_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_CP040998.1\|WP_000259718.1\|2200839_2202099_+\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
NZ_CP040998.1\|WP_000643988.1\|2203286_2203886_+\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP040998.1\|WP_000602937.1\|2202095_2202581_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_CP040998.1\|WP_000230173.1\|2203905_2204928_+\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP040998.1\|WP_000951058.1\|2207220_2207661_-\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP040998.1\|WP_000134528.1\|2200282_2200777_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
NZ_CP040998.1\|WP_000503820.1\|2199774_2200281_+\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65

>NZ_CP040998.1|WP_000230173.1|2203905_2204928_+|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP040998.1|WP_000643988.1|2203286_2203886_+|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP040998.1|WP_000866971.1|2203046_2203280_+|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP040998.1|WP_000808500.1|2202594_2203041_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP040998.1|WP_000602937.1|2202095_2202581_+|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP040998.1|WP_000259718.1|2200839_2202099_+|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP040998.1|WP_000134528.1|2200282_2200777_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_CP040998.1|WP_000503820.1|2199774_2200281_+|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP040998.1|WP_000076929.1|2198739_2199744_+|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP040998.1|WP_000913019.1|2197964_2198570_+|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG
>NZ_CP040998.1|WP_001790034.1|2205266_2205437_-|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP040998.1|WP_000066900.1|2205562_2205913_+|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP040998.1|WP_000184419.1|2206016_2207228_-|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP040998.1|WP_000951058.1|2207220_2207661_-|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP040998.1|WP_000600967.1|2207822_2208587_+|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP040998.1|WP_001549681.1|2208578_2208830_-|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP040998.1|WP_000413865.1|2209218_2210484_+|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP040998.1|WP_000592303.1|2210600_2213768_+|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP040998.1|WP_001161085.1|2213954_2214272_-|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP040998.1|WP_000051206.1|2214516_2214681_-|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD

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Crispr_ID: NZ_CP040998_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_11

2329222-2329372

Orphan

Consensus_repeat	Method
TGCATAAGAGCCCCTAACAACTAAAGTT	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NZ_CP040998_11

>merge|NZ_CP040998|11|2329222-2329372|CRISPRCasFinder
TAGAAAGAAGCCCCTAACAACTAAAGTTGAAAAATAGAGGAACACAGTTGGATGCTACGCATCAACTGCATAAGAGCCCCTAACAACTAAAGTTTAAAAGTAGGAGCGCCTGCGCTAAGCGCATGCATAAGAGCCCCTAACAACTAAAGTT

>NZ_CP040998|11|10|2329222-2329372|CRISPRCasFinder
TAGAAAGAAGCCCCTAACAACTAAAGTT	GAAAAATAGAGGAACACAGTTGGATGCTACGCATCAAC
TGCATAAGAGCCCCTAACAACTAAAGTT	TAAAAGTAGGAGCGCCTGCGCTAAGCGCA
TGCATAAGAGCCCCTAACAACTAAAGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_000115562.1\|2326962_2328099_+\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP040998.1\|WP_001790138.1\|2326581_2326674_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_001127960.1\|2333300_2334239_+\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP040998.1\|WP_000495671.1\|2329389_2330481_-\|lytic-regulatory-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000070866.1\|2337615_2338059_+\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP040998.1\|WP_000808817.1\|2334269_2334500_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000648719.1\|2316194_2317301_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP040998.1\|WP_001123303.1\|2337002_2337416_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP040998.1\|WP_000334465.1\|2322132_2323938_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP040998.1\|WP_000908177.1\|2324169_2324952_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP040998.1\|WP_000370924.1\|2325019_2325877_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP040998.1\|WP_000083807.1\|2319913_2321452_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP040998.1\|WP_000927363.1\|2317746_2319879_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP040998.1\|WP_001292149.1\|2317300_2317735_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP040998.1\|WP_000019744.1\|2330746_2331727_-\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP040998.1\|WP_001802298.1\|2328785_2328890_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000160304.1\|2338179_2338890_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP040998.1\|WP_001024094.1\|2332200_2332866_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP040998.1\|WP_000123393.1\|2335171_2336545_+\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP040998.1\|WP_000003759.1\|2331728_2332049_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_000115562.1\|2326962_2328099_+\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.8303e-06
NZ_CP040998.1\|WP_000123393.1\|2335171_2336545_+\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP040998.1\|WP_000003759.1\|2331728_2332049_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP040998.1\|WP_000070866.1\|2337615_2338059_+\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP040998.1\|WP_000648719.1\|2316194_2317301_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP040998.1\|WP_001123303.1\|2337002_2337416_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP040998.1\|WP_000334465.1\|2322132_2323938_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP040998.1\|WP_000908177.1\|2324169_2324952_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.86955e-104
NZ_CP040998.1\|WP_000370924.1\|2325019_2325877_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
NZ_CP040998.1\|WP_000083807.1\|2319913_2321452_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP040998.1\|WP_000927363.1\|2317746_2319879_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
NZ_CP040998.1\|WP_001292149.1\|2317300_2317735_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP040998.1\|WP_000019744.1\|2330746_2331727_-\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NZ_CP040998.1\|WP_000160304.1\|2338179_2338890_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP040998.1\|WP_001024094.1\|2332200_2332866_+\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
NZ_CP040998.1\|WP_001127960.1\|2333300_2334239_+\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129

>NZ_CP040998.1|WP_001802298.1|2328785_2328890_+|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP040998.1|WP_000115562.1|2326962_2328099_+|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPIKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>NZ_CP040998.1|WP_001790138.1|2326581_2326674_-|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>NZ_CP040998.1|WP_000370924.1|2325019_2325877_+|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>NZ_CP040998.1|WP_000908177.1|2324169_2324952_+|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP040998.1|WP_000334465.1|2322132_2323938_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP040998.1|WP_000083807.1|2319913_2321452_-|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP040998.1|WP_000927363.1|2317746_2319879_-|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP040998.1|WP_001292149.1|2317300_2317735_-|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP040998.1|WP_000648719.1|2316194_2317301_-|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP040998.1|WP_000495671.1|2329389_2330481_-|lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP040998.1|WP_000019744.1|2330746_2331727_-|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP040998.1|WP_000003759.1|2331728_2332049_-|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP040998.1|WP_001024094.1|2332200_2332866_+|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NZ_CP040998.1|WP_001127960.1|2333300_2334239_+|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP040998.1|WP_000808817.1|2334269_2334500_+|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP040998.1|WP_000123393.1|2335171_2336545_+|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP040998.1|WP_001123303.1|2337002_2337416_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP040998.1|WP_000070866.1|2337615_2338059_+|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP040998.1|WP_000160304.1|2338179_2338890_-|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE

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Crispr_ID: NZ_CP040998_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_12

2523420-2523498

Orphan

Consensus_repeat	Method
TGCAGGTTGGCGGGGCCCCAACA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP040998_12

>merge|NZ_CP040998|12|2523420-2523498|CRISPRCasFinder
TGCAGGTTGGCGGGGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACGATAATGTGCAGGTTGGCGGGGCCCCAACA

>NZ_CP040998|12|11|2523420-2523498|CRISPRCasFinder
TGCAGGTTGGCGGGGCCCCAACA	CAGAAGCTGACGAAAAGTCAGCTTACGATAATG
TGCAGGTTGGCGGGGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_001250336.1\|2518992_2520306_+\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP040998.1\|WP_001017131.1\|2525754_2526798_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP040998.1\|WP_000428172.1\|2529027_2529303_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000949467.1\|2518200_2518701_-\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP040998.1\|WP_000613733.1\|2517257_2517812_-\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP040998.1\|WP_000228666.1\|2529309_2529774_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP040998.1\|WP_001790679.1\|2518026_2518119_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000149064.1\|2525056_2525758_+\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP040998.1\|WP_001836289.1\|2516119_2517190_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP040998.1\|WP_000636142.1\|2523680_2524439_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP040998.1\|WP_001795438.1\|2530123_2531380_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP040998.1\|WP_000037075.1\|2527532_2528750_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP040998.1\|WP_000999713.1\|2522166_2523153_-\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP040998.1\|WP_001549145.1\|2521263_2521677_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000548781.1\|2515342_2515873_+\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP040998.1\|WP_001790257.1\|2521124_2521235_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000544969.1\|2520307_2521039_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP040998.1\|WP_001110179.1\|2524655_2525042_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040998.1\|WP_000153530.1\|2526787_2527417_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP040998.1\|WP_000180461.1\|2529920_2530121_+\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_001250336.1\|2518992_2520306_+\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	7.18737e-99
NZ_CP040998.1\|WP_000149064.1\|2525056_2525758_+\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP040998.1\|WP_000949467.1\|2518200_2518701_-\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_CP040998.1\|WP_000613733.1\|2517257_2517812_-\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.92778e-75
NZ_CP040998.1\|WP_000228666.1\|2529309_2529774_-\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP040998.1\|WP_001017131.1\|2525754_2526798_+\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP040998.1\|WP_001836289.1\|2516119_2517190_+\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP040998.1\|WP_000636142.1\|2523680_2524439_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NZ_CP040998.1\|WP_001795438.1\|2530123_2531380_+\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP040998.1\|WP_000037075.1\|2527532_2528750_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	4.24482e-85
NZ_CP040998.1\|WP_000999713.1\|2522166_2523153_-\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP040998.1\|WP_000153530.1\|2526787_2527417_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
NZ_CP040998.1\|WP_000548781.1\|2515342_2515873_+\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
NZ_CP040998.1\|WP_000544969.1\|2520307_2521039_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.33663e-121
NZ_CP040998.1\|WP_000180461.1\|2529920_2530121_+\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	2.44511e-24

>NZ_CP040998.1|WP_000999713.1|2522166_2523153_-|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP040998.1|WP_001549145.1|2521263_2521677_+|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDCDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>NZ_CP040998.1|WP_001790257.1|2521124_2521235_+|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP040998.1|WP_000544969.1|2520307_2521039_+|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>NZ_CP040998.1|WP_001250336.1|2518992_2520306_+|Mur-ligase-family-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLYLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP040998.1|WP_000949467.1|2518200_2518701_-|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP040998.1|WP_001790679.1|2518026_2518119_+|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP040998.1|WP_000613733.1|2517257_2517812_-|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKIHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP040998.1|WP_001836289.1|2516119_2517190_+|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGETAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP040998.1|WP_000548781.1|2515342_2515873_+|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>NZ_CP040998.1|WP_000636142.1|2523680_2524439_+|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP040998.1|WP_001110179.1|2524655_2525042_+|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP040998.1|WP_000149064.1|2525056_2525758_+|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP040998.1|WP_001017131.1|2525754_2526798_+|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP040998.1|WP_000153530.1|2526787_2527417_+|response-regulator-transcription-factor
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP040998.1|WP_000037075.1|2527532_2528750_-|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP040998.1|WP_000428172.1|2529027_2529303_-|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP040998.1|WP_000228666.1|2529309_2529774_-|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP040998.1|WP_000180461.1|2529920_2530121_+|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
>NZ_CP040998.1|WP_001795438.1|2530123_2531380_+|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAGKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF

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Crispr_ID: NZ_CP040998_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040998_13

2680074-2680297

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040998_13

>merge|NZ_CP040998|13|2680074-2680297|CRISPRCasFinder
CCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCC

>NZ_CP040998|13|12|2680074-2680297|CRISPRCasFinder
CCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCC	CGCCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCTTACC
CCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040998.1\|WP_001025061.1\|2664060_2665242_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP040998.1\|WP_000004335.1\|2676957_2678619_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP040998.1\|WP_000526539.1\|2662997_2663951_-\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
NZ_CP040998.1\|WP_000434765.1\|2683480_2684272_+\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|223584
NZ_CP040998.1\|WP_001266157.1\|2684286_2684931_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP040998.1\|WP_001048368.1\|2689203_2689800_+\|DUF4479-domain-containing-protein	unknown	unknown	gnl\|CDD\|234804
NZ_CP040998.1\|WP_001108732.1\|2665532_2667947_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_CP040998.1\|WP_001024576.1\|2686765_2687842_+\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NZ_CP040998.1\|WP_001051860.1\|2679327_2679750_+\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
NZ_CP040998.1\|WP_001836275.1\|2668605_2675166_+\|LPXTG-anchored-repetitive-surface-protein-SasC	unknown	unknown	gnl\|CDD\|275089
NZ_CP040998.1\|WP_001091387.1\|2688317_2689175_+\|DUF1444-domain-containing-protein	unknown	unknown	gnl\|CDD\|237463
NZ_CP040998.1\|WP_000265417.1\|2680669_2682079_+\|Mn(2+)-dependent-dipeptidase-Sapep	unknown	unknown	gnl\|CDD\|235988
NZ_CP040998.1\|WP_000764419.1\|2662437_2663001_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377744
NZ_CP040998.1\|WP_000163826.1\|2686367_2686679_-\|peptidase	unknown	unknown	gnl\|CDD\|227871
NZ_CP040998.1\|WP_000285019.1\|2675282_2676551_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|367519
NZ_CP040998.1\|WP_000689580.1\|2685400_2686243_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293814
NZ_CP040998.1\|WP_001217125.1\|2678615_2679311_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP040998.1\|WP_000836465.1\|2667968_2668280_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP040998.1\|WP_000811163.1\|2687906_2688218_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP040998.1\|WP_000411085.1\|2682082_2682931_+\|D-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|130191

Protein	Function_ID	Function_description	E-value
NZ_CP040998.1\|WP_001025061.1\|2664060_2665242_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66072e-94
NZ_CP040998.1\|WP_000004335.1\|2676957_2678619_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.63186e-123
NZ_CP040998.1\|WP_000526539.1\|2662997_2663951_-\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0
NZ_CP040998.1\|WP_000434765.1\|2683480_2684272_+\|phosphotransferase-family-protein	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	5.2385e-83
NZ_CP040998.1\|WP_001266157.1\|2684286_2684931_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.9831e-87
NZ_CP040998.1\|WP_001048368.1\|2689203_2689800_+\|DUF4479-domain-containing-protein	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	7.47641e-48
NZ_CP040998.1\|WP_001108732.1\|2665532_2667947_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP040998.1\|WP_001024576.1\|2686765_2687842_+\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	2.36515e-152
NZ_CP040998.1\|WP_001051860.1\|2679327_2679750_+\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000542053
NZ_CP040998.1\|WP_001836275.1\|2668605_2675166_+\|LPXTG-anchored-repetitive-surface-protein-SasC	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	2.97261e-115
NZ_CP040998.1\|WP_001091387.1\|2688317_2689175_+\|DUF1444-domain-containing-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
NZ_CP040998.1\|WP_000265417.1\|2680669_2682079_+\|Mn(2+)-dependent-dipeptidase-Sapep	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NZ_CP040998.1\|WP_000764419.1\|2662437_2663001_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.38341e-67
NZ_CP040998.1\|WP_000163826.1\|2686367_2686679_-\|peptidase	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.78628e-46
NZ_CP040998.1\|WP_000285019.1\|2675282_2676551_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0
NZ_CP040998.1\|WP_000689580.1\|2685400_2686243_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293814	cd07728, YtnP-like_MBL-fold, Bacillus subtilis YtnP and related proteins; MBL-fold metallo hydrolase domain. Bacillus subtilis YtnP inhibits the signaling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.38932e-155
NZ_CP040998.1\|WP_001217125.1\|2678615_2679311_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.1062e-94
NZ_CP040998.1\|WP_000836465.1\|2667968_2668280_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.46882e-25
NZ_CP040998.1\|WP_000811163.1\|2687906_2688218_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.34221e-24
NZ_CP040998.1\|WP_000411085.1\|2682082_2682931_+\|D-amino-acid-transaminase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	6.28892e-159

>NZ_CP040998.1|WP_001051860.1|2679327_2679750_+|YtxH-domain-containing-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFKEEKSKFTEYDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>NZ_CP040998.1|WP_001217125.1|2678615_2679311_+|rRNA-pseudouridine-synthase
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLTDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>NZ_CP040998.1|WP_000004335.1|2676957_2678619_+|polysaccharide-biosynthesis-protein
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNIHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>NZ_CP040998.1|WP_000285019.1|2675282_2676551_-|NAD(P)/FAD-dependent-oxidoreductase
MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHASME
>NZ_CP040998.1|WP_001836275.1|2668605_2675166_+|LPXTG-anchored-repetitive-surface-protein-SasC
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQATNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDVVSNNTALNVPTKTNENGSGGHLTLKEIQEDVRHSSNKPELVAIAEPASNRPKKRSRRAAPADPNATPADPAAAAVGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPTVNVVNNLPGFTLINGGKVGVFSHAMVRTSMFDSGDNKNYQAQGNVIALGRIHGTDTNDHGDFNGIEKALTVNPNSELIFEFNTMTTKNGQGATNVIIKNADTNDTIAEKTVEGGPTLRLFKVPDNVRNLKIQFVPKNDAITDARGIYQLKDGYKYYSFVDSIGLHSGSHVFVERRTMDPTATNNKEFTVTTSLKNNGNSGASLDTNDFVYQVQLPEGVEYVNNSLTKDFPSNNSGVDVNDMNVTYDAANRVITIKSTGGGTANSPARLMPDKILDLRYKLRVNNVPTPRTVTFNETLTYKTYTQDFINSAAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNGLKRRAQTILDENRNNVPLNKRVSQAYIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTIDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDALNQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNANVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDTRNVVNDKAREAITNINATTGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVTPDHIVRAAARDAVKQQYEAKKREIEQAEHATDEEKQVALNQLANNEKRALQNIDQAIANNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>NZ_CP040998.1|WP_000836465.1|2667968_2668280_+|rhodanese-like-domain-containing-protein
MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>NZ_CP040998.1|WP_001108732.1|2665532_2667947_+|leucine--tRNA-ligase
MNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLAIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>NZ_CP040998.1|WP_001025061.1|2664060_2665242_+|MFS-transporter
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>NZ_CP040998.1|WP_000526539.1|2662997_2663951_-|TIGR01212-family-radical-SAM-protein
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>NZ_CP040998.1|WP_000764419.1|2662437_2663001_-|methyltransferase-domain-containing-protein
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS
>NZ_CP040998.1|WP_000265417.1|2680669_2682079_+|Mn(2+)-dependent-dipeptidase-Sapep
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>NZ_CP040998.1|WP_000411085.1|2682082_2682931_+|D-amino-acid-transaminase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>NZ_CP040998.1|WP_000434765.1|2683480_2684272_+|phosphotransferase-family-protein
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>NZ_CP040998.1|WP_001266157.1|2684286_2684931_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>NZ_CP040998.1|WP_000689580.1|2685400_2686243_+|MBL-fold-metallo-hydrolase
MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVLGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDNGENIDAYILRETLVDNN
>NZ_CP040998.1|WP_000163826.1|2686367_2686679_-|peptidase
MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>NZ_CP040998.1|WP_001024576.1|2686765_2687842_+|M42-family-metallopeptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>NZ_CP040998.1|WP_000811163.1|2687906_2688218_+|thioredoxin-family-protein
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>NZ_CP040998.1|WP_001091387.1|2688317_2689175_+|DUF1444-domain-containing-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>NZ_CP040998.1|WP_001048368.1|2689203_2689800_+|DUF4479-domain-containing-protein
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	283192-283228	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	933962-933998	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	981452-981488	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	2521931-2521967	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	2521990-2522026	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	371503-371539	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	1097373-1097409	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	1605832-1605868	0	1.0
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	371561-371597	0	1.0
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	680510-680546	0	1.0
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	934018-934054	0	1.0
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	1379911-1379947	0	1.0
NZ_CP040998_1	1.3\|579829\|37\|NZ_CP040998\|CRT	579829-579865	37	NZ_CP040998.1	2205153-2205189	0	1.0
NZ_CP040998_3	3.1\|890917\|34\|NZ_CP040998\|CRISPRCasFinder	890917-890950	34	NZ_CP040998.1	283175-283208	0	1.0
NZ_CP040998_3	3.1\|890917\|34\|NZ_CP040998\|CRISPRCasFinder	890917-890950	34	NZ_CP040998.1	371523-371556	0	1.0
NZ_CP040998_9	9.1\|1762930\|17\|NZ_CP040998\|PILER-CR	1762930-1762946	17	NZ_CP040998.1	1462714-1462730	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	283147-283162	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	367172-367187	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	371569-371584	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	579669-579684	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	680523-680538	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	890620-890635	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	1379919-1379934	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	1928278-1928293	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	2205110-2205125	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	2512538-2512553	0	1.0
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	2512596-2512611	0	1.0
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	654313-654349	1	0.973
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	2038726-2038762	1	0.973
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	103388-103424	1	0.973
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	283134-283170	1	0.973
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	1928265-1928301	1	0.973
NZ_CP040998_1	1.3\|579829\|37\|NZ_CP040998\|CRT	579829-579865	37	NZ_CP040998.1	2680360-2680396	1	0.973
NZ_CP040998_2	2.2\|797772\|26\|NZ_CP040998\|CRT	797772-797797	26	NZ_CP040998.1	934001-934026	1	0.962
NZ_CP040998_4	4.1\|934057\|26\|NZ_CP040998\|CRISPRCasFinder	934057-934082	26	NZ_CP040998.1	579689-579714	1	0.962
NZ_CP040998_4	4.1\|934057\|26\|NZ_CP040998\|CRISPRCasFinder	934057-934082	26	NZ_CP040998.1	971065-971090	1	0.962
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	1379802-1379830	1	0.966
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	2680365-2680393	1	0.966
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	103401-103416	1	0.938
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	325522-325537	1	0.938
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	583749-583764	1	0.938
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	970989-971004	1	0.938
NZ_CP040998_9	9.2\|1763000\|16\|NZ_CP040998\|PILER-CR	1763000-1763015	16	NZ_CP040998.1	2115651-2115666	1	0.938
NZ_CP040998_12	12.1\|2523443\|33\|NZ_CP040998\|CRISPRCasFinder	2523443-2523475	33	NZ_CP040998.1	371569-371601	1	0.97
NZ_CP040998_12	12.1\|2523443\|33\|NZ_CP040998\|CRISPRCasFinder	2523443-2523475	33	NZ_CP040998.1	103384-103416	1	0.97
NZ_CP040998_12	12.1\|2523443\|33\|NZ_CP040998\|CRISPRCasFinder	2523443-2523475	33	NZ_CP040998.1	934014-934046	1	0.97
NZ_CP040998_12	12.1\|2523443\|33\|NZ_CP040998\|CRISPRCasFinder	2523443-2523475	33	NZ_CP040998.1	1928261-1928293	1	0.97
NZ_CP040998_1	1.1\|579717\|37\|NZ_CP040998\|CRT	579717-579753	37	NZ_CP040998.1	583685-583721	2	0.946
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	579661-579697	2	0.946
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	583741-583777	2	0.946
NZ_CP040998_1	1.2\|579773\|37\|NZ_CP040998\|CRT	579773-579809	37	NZ_CP040998.1	2205097-2205133	2	0.946
NZ_CP040998_1	1.3\|579829\|37\|NZ_CP040998\|CRT	579829-579865	37	NZ_CP040998.1	103446-103482	2	0.946
NZ_CP040998_1	1.3\|579829\|37\|NZ_CP040998\|CRT	579829-579865	37	NZ_CP040998.1	890877-890913	2	0.946
NZ_CP040998_1	1.3\|579829\|37\|NZ_CP040998\|CRT	579829-579865	37	NZ_CP040998.1	2512641-2512677	2	0.946
NZ_CP040998_1	1.3\|579829\|37\|NZ_CP040998\|CRT	579829-579865	37	NZ_CP040998.1	2013442-2013478	2	0.946
NZ_CP040998_2	2.2\|797772\|26\|NZ_CP040998\|CRT	797772-797797	26	NZ_CP040998.1	1379939-1379964	2	0.923
NZ_CP040998_2	2.4\|797886\|26\|NZ_CP040998\|CRT	797886-797911	26	NZ_CP040998.1	579689-579714	2	0.923
NZ_CP040998_2	2.4\|797886\|26\|NZ_CP040998\|CRT	797886-797911	26	NZ_CP040998.1	971065-971090	2	0.923
NZ_CP040998_2	2.5\|797912\|33\|NZ_CP040998\|CRISPRCasFinder	797912-797944	33	NZ_CP040998.1	890613-890645	2	0.939
NZ_CP040998_4	4.1\|934057\|26\|NZ_CP040998\|CRISPRCasFinder	934057-934082	26	NZ_CP040998.1	971009-971034	2	0.923
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	2013447-2013475	2	0.931
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	103449-103477	2	0.931
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	778244-778272	2	0.931
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	890880-890908	2	0.931
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	2205156-2205184	2	0.931
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	NZ_CP040998.1	2512644-2512672	2	0.931
NZ_CP040998_12	12.1\|2523443\|33\|NZ_CP040998\|CRISPRCasFinder	2523443-2523475	33	NZ_CP040998.1	283130-283162	2	0.939

1. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 283192-283228, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

2. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 933962-933998, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

3. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 981452-981488, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

4. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 2521931-2521967, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

5. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 2521990-2522026, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

6. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 371503-371539, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

7. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 1097373-1097409, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

8. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 1605832-1605868, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

9. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 371561-371597, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

10. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 680510-680546, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

11. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 934018-934054, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

12. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 1379911-1379947, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

13. spacer 1.3|579829|37|NZ_CP040998|CRT matches to position: 2205153-2205189, mismatch: 0, identity: 1.0

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttctttttgaaattc	Protospacer
*************************************

14. spacer 3.1|890917|34|NZ_CP040998|CRISPRCasFinder matches to position: 283175-283208, mismatch: 0, identity: 1.0

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
**********************************

15. spacer 3.1|890917|34|NZ_CP040998|CRISPRCasFinder matches to position: 371523-371556, mismatch: 0, identity: 1.0

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
**********************************

16. spacer 9.1|1762930|17|NZ_CP040998|PILER-CR matches to position: 1462714-1462730, mismatch: 0, identity: 1.0

aagaatttcgaaaagaa	CRISPR spacer
aagaatttcgaaaagaa	Protospacer
*****************

17. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 283147-283162, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

18. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 367172-367187, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

19. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 371569-371584, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

20. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 579669-579684, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

21. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 680523-680538, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

22. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 890620-890635, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

23. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 1379919-1379934, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

24. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 1928278-1928293, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

25. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 2205110-2205125, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

26. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 2512538-2512553, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

27. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 2512596-2512611, mismatch: 0, identity: 1.0

tcagcttacaataatg	CRISPR spacer
tcagcttacaataatg	Protospacer
****************

28. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 654313-654349, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttacattgtctgtagaaattgggaatccaatttc	Protospacer
*****.*******************************

29. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 2038726-2038762, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctctagaaattgggaatccaatttc	Protospacer
************** **********************

30. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 103388-103424, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattatagtaagctgacttttcgtcagct	Protospacer
************** **********************

31. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 283134-283170, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcatct	Protospacer
********************************** **

32. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 1928265-1928301, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aactcgcacattattgtaagctgacttttcgtcagct	Protospacer
****.********************************

33. spacer 1.3|579829|37|NZ_CP040998|CRT matches to position: 2680360-2680396, mismatch: 1, identity: 0.973

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttcttttcgaaattc	Protospacer
*****************************.*******

34. spacer 2.2|797772|26|NZ_CP040998|CRT matches to position: 934001-934026, mismatch: 1, identity: 0.962

tcgccagcttctgtgttggggccccg	CRISPR spacer
tcgtcagcttctgtgttggggccccg	Protospacer
***.**********************

35. spacer 4.1|934057|26|NZ_CP040998|CRISPRCasFinder matches to position: 579689-579714, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
*************.************

36. spacer 4.1|934057|26|NZ_CP040998|CRISPRCasFinder matches to position: 971065-971090, mismatch: 1, identity: 0.962

cggggccccaacacagaagctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
******************** *****

37. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 1379802-1379830, mismatch: 1, identity: 0.966

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaagcaatgca	Protospacer
*********************.*******

38. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 2680365-2680393, mismatch: 1, identity: 0.966

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacagacaatgca	Protospacer
********************.********

39. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 103401-103416, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttactataatg	Protospacer
********* ******

40. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 325522-325537, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacaacaatg	Protospacer
***********.****

41. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 583749-583764, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacaaaaatg	Protospacer
*********** ****

42. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 970989-971004, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagctaacaataatg	Protospacer
****** *********

43. spacer 9.2|1763000|16|NZ_CP040998|PILER-CR matches to position: 2115651-2115666, mismatch: 1, identity: 0.938

tcagcttacaataatg	CRISPR spacer
tcagcttacaacaatg	Protospacer
***********.****

44. spacer 12.1|2523443|33|NZ_CP040998|CRISPRCasFinder matches to position: 371569-371601, mismatch: 1, identity: 0.97

cagaagctgacgaaaagtcagcttacgataatg	CRISPR spacer
cagaagctgacgaaaagtcagcttacaataatg	Protospacer
**************************.******

45. spacer 12.1|2523443|33|NZ_CP040998|CRISPRCasFinder matches to position: 103384-103416, mismatch: 1, identity: 0.97

cagaagctgacgaaaagtcagcttacgataatg	CRISPR spacer
cagaagctgacgaaaagtcagcttactataatg	Protospacer
************************** ******

46. spacer 12.1|2523443|33|NZ_CP040998|CRISPRCasFinder matches to position: 934014-934046, mismatch: 1, identity: 0.97

cagaagctgacgaaaagtcagcttacgataatg	CRISPR spacer
cagaagctgacgaaaagtcagcttacaataatg	Protospacer
**************************.******

47. spacer 12.1|2523443|33|NZ_CP040998|CRISPRCasFinder matches to position: 1928261-1928293, mismatch: 1, identity: 0.97

cagaagctgacgaaaagtcagcttacgataatg	CRISPR spacer
cagaagctgacgaaaagtcagcttacaataatg	Protospacer
**************************.******

48. spacer 1.1|579717|37|NZ_CP040998|CRT matches to position: 583685-583721, mismatch: 2, identity: 0.946

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattggggttccaatttc	Protospacer
**************************. *********

49. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 579661-579697, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

50. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 583741-583777, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacatttttgtaagctgacttttcgccagct	Protospacer
************ ******************.*****

51. spacer 1.2|579773|37|NZ_CP040998|CRT matches to position: 2205097-2205133, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttctgtcagct	Protospacer
****************************..*******

52. spacer 1.3|579829|37|NZ_CP040998|CRT matches to position: 103446-103482, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

53. spacer 1.3|579829|37|NZ_CP040998|CRT matches to position: 890877-890913, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

54. spacer 1.3|579829|37|NZ_CP040998|CRT matches to position: 2512641-2512677, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttcctttcgaaattc	Protospacer
*************************.***.*******

55. spacer 1.3|579829|37|NZ_CP040998|CRT matches to position: 2013442-2013478, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

56. spacer 2.2|797772|26|NZ_CP040998|CRT matches to position: 1379939-1379964, mismatch: 2, identity: 0.923

tcgccagcttctgtgttggggccccg	CRISPR spacer
tcgtcagcttctttgttggggccccg	Protospacer
***.******** *************

57. spacer 2.4|797886|26|NZ_CP040998|CRT matches to position: 579689-579714, mismatch: 2, identity: 0.923

ccgccagcctctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
********.***.*************

58. spacer 2.4|797886|26|NZ_CP040998|CRT matches to position: 971065-971090, mismatch: 2, identity: 0.923

ccgccagcctctgtgttggggccccg	CRISPR spacer
ccgcctgcttctgtgttggggccccg	Protospacer
***** **.*****************

59. spacer 2.5|797912|33|NZ_CP040998|CRISPRCasFinder matches to position: 890613-890645, mismatch: 2, identity: 0.939

ccaacttgcacactattgtaagctgactttcca	CRISPR spacer
ccaacttgcacattattgtaagctgacttacca	Protospacer
************.**************** ***

60. spacer 4.1|934057|26|NZ_CP040998|CRISPRCasFinder matches to position: 971009-971034, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcaggcgg	Protospacer
*************.****** *****

61. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 2013447-2013475, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

62. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 103449-103477, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

63. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 778244-778272, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

64. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 890880-890908, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaagaaattctacaggcaatgca	Protospacer
********************..*******

65. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 2205156-2205184, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcaaaaagaaattctacagacaatgca	Protospacer
****.***************.********

66. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to position: 2512644-2512672, mismatch: 2, identity: 0.931

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
tttcgaaaggaaattctacagacaatgca	Protospacer
********.***********.********

67. spacer 12.1|2523443|33|NZ_CP040998|CRISPRCasFinder matches to position: 283130-283162, mismatch: 2, identity: 0.939

cagaagctgacgaaaagtcagcttacgataatg	CRISPR spacer
cagaagatgacgaaaagtcagcttacaataatg	Protospacer
****** *******************.******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040998_2	2.1\|797689\|53\|NZ_CP040998\|CRT	797689-797741	53	MG543995	Staphylococcus phage UPMK_1, partial genome	76246-76298	4	0.925
NZ_CP040998_2	2.2\|797772\|26\|NZ_CP040998\|CRT	797772-797797	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_CP040998_4	4.1\|934057\|26\|NZ_CP040998\|CRISPRCasFinder	934057-934082	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_CP040998_4	4.1\|934057\|26\|NZ_CP040998\|CRISPRCasFinder	934057-934082	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
NZ_CP040998_4	4.1\|934057\|26\|NZ_CP040998\|CRISPRCasFinder	934057-934082	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808
NZ_CP040998_5	5.1\|939456\|29\|NZ_CP040998\|CRISPRCasFinder	939456-939484	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
NZ_CP040998_12	12.1\|2523443\|33\|NZ_CP040998\|CRISPRCasFinder	2523443-2523475	33	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159745-159777	10	0.697

1. spacer 2.1|797689|53|NZ_CP040998|CRT matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 4, identity: 0.925

ttgggagtgggacagaaatgatattttcgcaaaatttatttcgtcgtcccacc	CRISPR spacer
aagggagtgggacagaaatgatagtttctcaaaatttatttcgtcgtcccacc	Protospacer
  ********************* **** ************************

2. spacer 2.2|797772|26|NZ_CP040998|CRT matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

tcgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

3. spacer 4.1|934057|26|NZ_CP040998|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcgg	CRISPR spacer
taaggcctcaacacagaagctggcgt	Protospacer
...****.*****************

4. spacer 4.1|934057|26|NZ_CP040998|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcgg	CRISPR spacer
gtaggcccagacacagaagctggcgg	Protospacer
  .***** .****************

5. spacer 4.1|934057|26|NZ_CP040998|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

cggggccccaacacagaagctggcgg	CRISPR spacer
tcagggccaaacacagaagctggcgg	Protospacer
. .** ** *****************

6. spacer 5.1|939456|29|NZ_CP040998|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tttcgaaaagaaattctacaaacaatgca	CRISPR spacer
cacttagaagaaatcctacaaacaatgca	Protospacer
. .. *.*******.**************

7. spacer 12.1|2523443|33|NZ_CP040998|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 10, identity: 0.697

cagaagctgacgaaaagtcagcttacgataatg	CRISPR spacer
aggtgcttgacgaaaactcaccttacgataaaa	Protospacer
 .* . .********* *** ********** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

45361 : 54404

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001005767.1\|45361_46366_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_001019172.1\|46367_47393_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|47415_48555_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|48573_48834_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_000749795.1\|49108_51388_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_000594993.1\|51590_53864_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
WP_000364542.1\|53885_54404_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_2

123542 : 131854

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217261.1\|123542_125342_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0
WP_001283055.1\|125565_126672_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_000624584.1\|126802_127480_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000683931.1\|127482_128583_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_001062180.1\|128696_130043_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
WP_000924214.1\|130052_130943_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001213908.1\|131068_131854_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3

DBSCAN-SWA_3

670559 : 679032

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000238664.1\|670559_671126_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1
WP_000030812.1\|671128_672157_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000483713.1\|672149_673634_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000032727.1\|673612_675802_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000666799.1\|675794_676466_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000848350.1\|676467_676731_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174053.1\|676730_677435_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_002871056.1\|677438_678563_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000861572.1\|678549_679032_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_4

835694 : 882618

Staphylococcus_phage(94.37%)

head,holin,plate,portal,capsid,terminase,integrase,tail

attL 849768:849784|attR 884515:884531

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000382163.1\|835694_835895_-	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0
WP_000139423.1\|835881_835992_-	hypothetical protein	W5R8J7	Staphylococcus_phage	1.7e-12	100.0
WP_001788502.1\|836062_836215_-	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	3.1e-20	100.0
WP_001035620.1\|836589_837147_+	DUF4888 domain-containing protein	A0A0F6N4L1	Staphylococcus_phage	7.4e-96	100.0
WP_001141517.1\|837206_838619_-	CHAP domain-containing protein	A0A0F6N3N1	Staphylococcus_phage	5.8e-286	100.0
WP_000351119.1\|838605_838881_-\|holin	phage holin	A0A0F6N3M0	Staphylococcus_phage	8.6e-45	100.0
WP_000398872.1\|838936_839332_-	hypothetical protein	A0A0F6N3G8	Staphylococcus_phage	1.2e-68	100.0
WP_000276662.1\|839337_840576_-\|plate	BppU family phage baseplate upper protein	A0A0F6N3G7	Staphylococcus_phage	1.6e-210	100.0
WP_001836236.1\|840588_842487_-	CHAP domain-containing protein	A0A0F6N4K6	Staphylococcus_phage	0.0e+00	100.0
WP_000466777.1\|842623_842923_-	DUF2951 domain-containing protein	A0A0F6N3M6	Staphylococcus_phage	9.9e-47	100.0
WP_000782200.1\|842962_843136_-	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
WP_000705896.1\|843139_843517_-	DUF2977 domain-containing protein	A0A0F6N3G4	Staphylococcus_phage	1.5e-60	100.0
WP_000634521.1\|843516_845340_-\|plate	phage baseplate upper protein	A0A0F6N3G2	Staphylococcus_phage	0.0e+00	100.0
WP_001836235.1\|845339_847250_-	hypothetical protein	A0A0F6N4K2	Staphylococcus_phage	0.0e+00	100.0
WP_000152718.1\|847264_849163_-	peptidase	A0A0F6N3M1	Staphylococcus_phage	0.0e+00	100.0
WP_000350675.1\|849171_850119_-\|tail	phage tail family protein	A0A0F6N3L4	Staphylococcus_phage	2.8e-183	100.0
849768:849784	attL	NA	NA	NA	NA
WP_000141480.1\|850131_853599_-	hypothetical protein	A0A0F6N3F9	Staphylococcus_phage	4.2e-245	100.0
WP_000105584.1\|853615_853960_-	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
WP_001100161.1\|853989_854355_-	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	3.6e-59	100.0
WP_000002577.1\|854416_854998_-\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	4.9e-106	100.0
WP_000188649.1\|855016_855400_-	hypothetical protein	A0A0F6N3L1	Staphylococcus_phage	1.5e-68	100.0
WP_001017815.1\|855411_855759_-	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
WP_025175363.1\|855758_856061_-	hypothetical protein	B2ZYY8	Staphylococcus_phage	7.4e-50	98.0
WP_000208960.1\|856057_856390_-\|head,tail	phage head-tail connector protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
WP_001836234.1\|856398_856686_-	hypothetical protein	A0A0F6N4J3	Staphylococcus_phage	1.6e-46	100.0
WP_001836233.1\|856707_857682_-\|capsid	phage major capsid protein	A0A0F6N3L5	Staphylococcus_phage	3.7e-183	100.0
WP_000392146.1\|857695_858316_-	DUF4355 domain-containing protein	A0A0F6N3K8	Staphylococcus_phage	2.1e-70	100.0
WP_000072208.1\|858424_858595_-	hypothetical protein	A0A0F6N3E9	Staphylococcus_phage	1.5e-23	100.0
WP_001133044.1\|858667_859663_-\|head	phage head morphogenesis protein	A0A0F6N3F1	Staphylococcus_phage	2.0e-184	100.0
WP_000909970.1\|859669_861208_-\|portal	phage portal protein	A0A0F6N4I8	Staphylococcus_phage	2.4e-293	100.0
WP_001836232.1\|861218_862514_-\|terminase	PBSX family phage terminase large subunit	A0A0F6N3L3	Staphylococcus_phage	2.0e-256	99.8
WP_001038244.1\|862516_863011_-\|terminase	terminase small subunit	A0A0F6N3K6	Staphylococcus_phage	7.8e-89	100.0
WP_000162701.1\|863198_863621_-	RinA family phage transcriptional activator	A0A0F6N3E5	Staphylococcus_phage	1.2e-74	100.0
WP_000990005.1\|863644_863791_-	hypothetical protein	B2ZYX7	Staphylococcus_phage	2.2e-15	100.0
WP_001657250.1\|863791_863965_-	transcriptional activator RinB	A0A0F6N3E7	Staphylococcus_phage	2.2e-22	100.0
WP_001072794.1\|863957_864161_-	hypothetical protein	B2ZYX5	Staphylococcus_phage	8.8e-31	98.5
WP_000132920.1\|864157_864352_-	hypothetical protein	S4SX95	Staphylococcus_phage	7.9e-29	100.0
WP_000195785.1\|864348_864555_-	DUF1381 domain-containing protein	A0A0F6N4I4	Staphylococcus_phage	1.1e-20	100.0
WP_000185651.1\|864591_865122_-	dUTP pyrophosphatase	A0A0F6N3L0	Staphylococcus_phage	1.7e-94	100.0
WP_000028421.1\|865114_865297_-	hypothetical protein	A0EWY1	Staphylococcus_phage	1.0e-25	98.3
WP_001836226.1\|865286_865538_-	DUF1024 family protein	A0A1W6JPK6	Staphylococcus_phage	2.1e-37	98.8
WP_001557190.1\|865530_865902_-	hypothetical protein	A0A0F6N3K4	Staphylococcus_phage	3.6e-54	100.0
WP_001562543.1\|865910_866153_-	phage protein	A0A0F6N3E1	Staphylococcus_phage	6.6e-41	100.0
WP_000029376.1\|866156_866513_-	hypothetical protein	A0A0F6N3E3	Staphylococcus_phage	6.5e-61	100.0
WP_000101252.1\|866640_866946_-	hypothetical protein	A0A0F6N4H9	Staphylococcus_phage	1.7e-49	100.0
WP_001187243.1\|866946_867132_-	DUF3113 family protein	A0A0F6N3K7	Staphylococcus_phage	1.1e-27	100.0
WP_001836225.1\|867136_867541_-	DUF1064 domain-containing protein	A1KX76	Staphylococcus_virus	3.6e-68	99.3
WP_001123695.1\|867550_867772_-	DUF3269 family protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
WP_000256589.1\|867784_867943_-	hypothetical protein	A0A2H4PQI7	Staphylococcus_phage	4.5e-22	100.0
WP_000803062.1\|867936_868716_-	ATP-binding protein	G4KNP1	Staphylococcus_phage	3.8e-146	100.0
WP_001836222.1\|868725_869496_-	hypothetical protein	G4KNP0	Staphylococcus_phage	9.3e-121	99.6
WP_000414755.1\|869561_869843_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
WP_000057263.1\|869981_870656_-	hypothetical protein	A1KX69	Staphylococcus_virus	3.9e-131	100.0
WP_001099009.1\|870667_871111_-	single-stranded DNA-binding protein	A0A2I6PD99	Staphylococcus_phage	1.8e-76	100.0
WP_000840496.1\|871107_871758_-	single-stranded DNA-binding protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
WP_001004336.1\|871758_872295_-	hypothetical protein	A0A0F6N4M6	Staphylococcus_phage	1.4e-80	100.0
WP_001836221.1\|872307_872568_-	DUF1108 family protein	A0A0F6N3P1	Staphylococcus_phage	1.2e-43	100.0
WP_000165363.1\|872572_872875_-	DUF2482 family protein	A0A0F6N3N3	Staphylococcus_phage	1.4e-48	100.0
WP_000066011.1\|872968_873130_-	DUF1270 domain-containing protein	Q4ZAZ7	Staphylococcus_virus	2.5e-20	100.0
WP_000977381.1\|873122_873344_-	hypothetical protein	A0A0F6N3I2	Staphylococcus_phage	1.5e-31	100.0
WP_001836220.1\|873357_873807_-	hypothetical protein	A0A0F6N3I1	Staphylococcus_phage	3.0e-79	100.0
WP_000187184.1\|873846_874071_-	hypothetical protein	A0A0F6N4M2	Staphylococcus_phage	3.2e-34	100.0
WP_001002757.1\|874071_874839_-	phage antirepressor Ant	A0A0F6N3N8	Staphylococcus_phage	1.1e-142	100.0
WP_000108122.1\|874838_875033_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	1.1e-25	100.0
WP_001055143.1\|875295_875628_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	4.1e-57	100.0
WP_000775187.1\|875644_876319_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	4.9e-126	100.0
WP_000661437.1\|876346_877072_+	hypothetical protein	A0A0F6N4L7	Staphylococcus_phage	9.9e-125	100.0
WP_000391592.1\|877103_878009_+	hypothetical protein	A0A0F6N3N6	Staphylococcus_phage	1.4e-168	100.0
WP_000143212.1\|877945_878146_-	excisionase	Q38044	Staphylococcus_phage	5.6e-30	100.0
WP_001145725.1\|878257_879307_+\|integrase	site-specific integrase	A0A0F6N3M4	Staphylococcus_phage	9.1e-204	100.0
WP_001074405.1\|879374_880772_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_001010508.1\|880922_881387_-	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_000807671.1\|881376_882618_-	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.5
884515:884531	attR	NA	NA	NA	NA

DBSCAN-SWA_5

967875 : 982606

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000616842.1\|967875_968637_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6
WP_001245578.1\|968633_969590_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000876318.1\|969576_970548_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_000499195.1\|970586_970742_-	hypothetical protein	NA	NA	NA	NA
WP_000562498.1\|971255_972227_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000855505.1\|972344_974450_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000692521.1\|974412_974811_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_001068497.1\|975611_976478_+	DMT family transporter	NA	NA	NA	NA
WP_000930014.1\|976497_976998_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_000193751.1\|977338_978844_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_001790641.1\|978921_979023_-	hypothetical protein	NA	NA	NA	NA
WP_000429014.1\|979113_980031_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_000197271.1\|980654_981197_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_001836199.1\|981547_982606_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.4

DBSCAN-SWA_6

994578 : 1002398

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217785.1\|994578_995730_-	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7
WP_000604514.1\|995713_996307_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_000446724.1\|996657_997326_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000941336.1\|997327_997747_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_001062972.1\|997750_998464_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000637687.1\|998562_999147_+	hypothetical protein	NA	NA	NA	NA
WP_001093553.1\|999426_999867_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001037807.1\|1000208_1000682_+	DoxX family protein	NA	NA	NA	NA
WP_000149344.1\|1000656_1001343_+	response regulator transcription factor	NA	NA	NA	NA
WP_000244412.1\|1001342_1002398_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	2.1e-14	30.0

DBSCAN-SWA_7

2558234 : 2659277

101

Staphylococcus_phage(89.66%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047930299.1\|2558234_2559338_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_153801567.1\|2559319_2559472_-	hypothetical protein	NA	NA	NA	NA
WP_000063582.1\|2559928_2560990_+	PTS transporter subunit IIC	NA	NA	NA	NA
WP_000649907.1\|2561247_2562705_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_001144055.1\|2562691_2563420_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-36	42.7
WP_001789049.1\|2563555_2564698_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_000181398.1\|2564702_2565173_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_001251224.1\|2565331_2565931_+	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
WP_000031108.1\|2565955_2566108_+	hypothetical protein	NA	NA	NA	NA
WP_000901021.1\|2566884_2567280_+	hypothetical protein	NA	NA	NA	NA
WP_000116224.1\|2567475_2568861_+	class II fumarate hydratase	NA	NA	NA	NA
WP_000669376.1\|2569323_2570145_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000437967.1\|2570307_2571420_+	GAF domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_001045133.1\|2571441_2572065_+	response regulator transcription factor	NA	NA	NA	NA
WP_000375864.1\|2572420_2572885_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000992527.1\|2573063_2574188_+	DUF445 domain-containing protein	NA	NA	NA	NA
WP_000290301.1\|2574256_2574601_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
WP_001791795.1\|2574983_2575082_+	hypothetical protein	NA	NA	NA	NA
WP_000238227.1\|2575372_2576569_+	exonuclease SbcCD subunit D	NA	NA	NA	NA
WP_000584648.1\|2576558_2579495_+	AAA family ATPase	NA	NA	NA	NA
WP_001244175.1\|2579491_2580433_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
WP_000782121.1\|2580553_2581516_-	foldase	NA	NA	NA	NA
WP_000477959.1\|2581720_2582278_-	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_000648118.1\|2583010_2583376_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_000004981.1\|2583517_2583940_-	HIT family protein	NA	NA	NA	NA
WP_000216878.1\|2584073_2584814_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8
WP_001836284.1\|2584806_2586030_+	ABC transporter permease	NA	NA	NA	NA
WP_000737976.1\|2586153_2586657_-	signal transduction protein TraP	NA	NA	NA	NA
WP_001790154.1\|2586819_2586930_+	hypothetical protein	NA	NA	NA	NA
WP_000233526.1\|2586919_2587957_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_000162881.1\|2588014_2588938_+	ferrochelatase	NA	NA	NA	NA
WP_000167538.1\|2588961_2590362_+	protoporphyrinogen oxidase	NA	NA	NA	NA
WP_000132889.1\|2590684_2591239_+	serine hydrolase family protein	NA	NA	NA	NA
WP_000206350.1\|2593695_2594484_-	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8
WP_001790220.1\|2594496_2595036_-	hypothetical protein	Q4ZCB9	Staphylococcus_virus	2.0e-61	76.8
WP_000878802.1\|2595849_2596770_+	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	2.3e-174	100.0
WP_000782464.1\|2596771_2597755_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000416759.1\|2597996_2598140_+	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000416756.1\|2598876_2599020_+	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_001092605.1\|2599084_2602078_+	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
WP_000566596.1\|2602070_2603315_+	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_000504439.1\|2603330_2603849_+	enterotoxin	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000691541.1\|2603858_2605232_+	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_001096791.1\|2605254_2605947_+	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000581552.1\|2605943_2606705_+	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_000586140.1\|2606701_2607400_+	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_001092763.1\|2607873_2608440_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_001836281.1\|2609403_2610111_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	1.7e-129	99.6
WP_001039447.1\|2610235_2610958_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_001836279.1\|2611015_2611735_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	2.1e-130	98.7
WP_001038704.1\|2611855_2612575_+\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_011447030.1\|2612523_2612631_-	hypothetical protein	NA	NA	NA	NA
WP_001038759.1\|2612732_2613449_+\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_001038688.1\|2613599_2614319_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001791797.1\|2614383_2614518_+	hypothetical protein	NA	NA	NA	NA
WP_001793440.1\|2614498_2616238_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
WP_000072624.1\|2616230_2617430_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	8.5e-230	100.0
WP_000831218.1\|2618279_2622392_+	SMEK domain-containing protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
WP_002868972.1\|2622929_2623289_+	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001791893.1\|2623636_2623738_-	hypothetical protein	NA	NA	NA	NA
WP_001801861.1\|2623860_2623956_-	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001549059.1\|2624158_2624302_+\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_000070812.1\|2624905_2625289_+	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|2625299_2625476_+	hypothetical protein	NA	NA	NA	NA
WP_000809857.1\|2625477_2625663_+	hypothetical protein	NA	NA	NA	NA
WP_000494956.1\|2625776_2626418_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
WP_000414205.1\|2626635_2627187_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
WP_000627551.1\|2627284_2627629_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
WP_000669046.1\|2627669_2628296_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
WP_000070653.1\|2628371_2629367_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
WP_001795535.1\|2629447_2630098_-	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_011443643.1\|2630400_2630856_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_000348360.1\|2631014_2632493_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
WP_000778523.1\|2632497_2633499_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
WP_000718107.1\|2633495_2633753_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000672014.1\|2633818_2634292_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_002868962.1\|2634296_2635043_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.1e-142	98.4
WP_000093392.1\|2635417_2635903_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
WP_000109906.1\|2636038_2637631_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000933822.1\|2638001_2639195_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000366154.1\|2639319_2640228_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
WP_000453320.1\|2640439_2641273_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
WP_000623471.1\|2643356_2643710_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_001200542.1\|2643706_2644072_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000091445.1\|2644327_2644630_-	hypothetical protein	NA	NA	NA	NA
WP_001096494.1\|2644889_2645603_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_001168904.1\|2646042_2646678_-\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001030465.1\|2646973_2647417_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
WP_001153742.1\|2647403_2647847_-	competence protein ComK	NA	NA	NA	NA
WP_000671063.1\|2647959_2648430_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	3.3e-81	98.1
WP_000384171.1\|2648628_2648853_+	hypothetical protein	NA	NA	NA	NA
WP_001032833.1\|2649128_2649983_+	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000163235.1\|2650277_2650673_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_000989123.1\|2650690_2651983_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.9e-227	99.3
WP_000221179.1\|2651982_2652297_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_001261681.1\|2652819_2654322_+	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000384181.1\|2654814_2655846_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.8e-197	99.4
WP_000493892.1\|2655852_2656485_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_001159022.1\|2656495_2657677_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_001008551.1\|2657689_2658154_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001196354.1\|2658275_2659277_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7

DBSCAN-SWA_8

2662437 : 2675166

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000764419.1\|2662437_2663001_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000526539.1\|2662997_2663951_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_001025061.1\|2664060_2665242_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_001108732.1\|2665532_2667947_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_000836465.1\|2667968_2668280_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001836275.1\|2668605_2675166_+	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.3e-303	97.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP040999

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP040998

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection