CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP041168	Streptomyces griseorubiginosus strain BTU6 chromosome, complete genome	14 crisprs	csa3,WYL,DEDDh,cas4,Cas9_archaeal,cas3,Cas14u_CAS-V,DinG	4	5	0	0

1. NZ_CP041168

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041168_1

• CRISPR_ID: NZ_CP041168_1
• CRISPR_location: 1329039-1329145
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_1

Consensus_repeat	Method
CCGATCCCGGGGTCCAGGGTCCGGTC	CRISPRCasFinder

spacers of NZ_CP041168_1

>1.1|1329065|55|NZ_CP041168|CRISPRCasFinder
AGCGGTCCCGAAGCCAGGGGTCCGGCAGGCGATCCCGAACCCAGGAGTCCGGCCG

CRISPR arrays and Neighbor proteins around NZ_CP041168_1

CRISPR arrays

The CRISPR arrays of NZ_CP041168_1

>merge|NZ_CP041168|1|1329039-1329145|CRISPRCasFinder
CCGATCCCGGGGTCCAGGGTCCGGTCAGCGGTCCCGAAGCCAGGGGTCCGGCAGGCGATCCCGAACCCAGGAGTCCGGCCGCCGATCCCGAGGTCCAGGGTCCGGTC

>NZ_CP041168|1|1|1329039-1329145|CRISPRCasFinder
CCGATCCCGGGGTCCAGGGTCCGGTC	AGCGGTCCCGAAGCCAGGGGTCCGGCAGGCGATCCCGAACCCAGGAGTCCGGCCG
CCGATCCCGAGGTCCAGGGTCCGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141203682.1|1327019_1328078_-|acyl-CoA-desaturase	unknown	unknown	gnl|CDD|239583
NZ_CP041168.1|WP_141203680.1|1325238_1325535_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141203684.1|1333730_1334897_-|xylose-isomerase	unknown	unknown	gnl|CDD|237170
NZ_CP041168.1|WP_141203689.1|1341125_1342649_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143434
NZ_CP041168.1|WP_141203675.1|1320944_1321544_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225136
NZ_CP041168.1|WP_141203681.1|1325670_1326663_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141203677.1|1322453_1323011_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP041168.1|WP_141203679.1|1323625_1325053_-|monooxygenase	unknown	unknown	gnl|CDD|223727
NZ_CP041168.1|WP_141203687.1|1339091_1339691_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP041168.1|WP_141203674.1|1320018_1320792_-|hypothetical-protein	unknown	unknown	gnl|CDD|225837
NZ_CP041168.1|WP_141203690.1|1344975_1345575_-|hypothetical-protein	unknown	unknown	gnl|CDD|373064
NZ_CP041168.1|WP_141203676.1|1321590_1322346_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP041168.1|WP_141209114.1|1336640_1337801_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP041168.1|WP_020137233.1|1326716_1326899_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141203678.1|1323089_1323575_+|VOC-family-protein	unknown	unknown	gnl|CDD|319910
NZ_CP041168.1|WP_141203686.1|1338049_1339063_+|acetamidase	unknown	unknown	gnl|CDD|225279
NZ_CP041168.1|WP_141209113.1|1333043_1333274_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141203683.1|1331265_1332540_+|SWF-or-SNF-family-helicase	unknown	unknown	gnl|CDD|226729
NZ_CP041168.1|WP_141203688.1|1339788_1341069_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|225822
NZ_CP041168.1|WP_141203685.1|1335043_1336489_+|xylulokinase	unknown	unknown	gnl|CDD|198375

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141203682.1|1327019_1328078_-|acyl-CoA-desaturase	gnl|CDD|239583	cd03506, Delta6-FADS-like, The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases are required for the synthesis of highly unsaturated fatty acids (HUFAs), which are mainly esterified into phospholipids and contribute to maintaining membrane fluidity. While HUFAs may be required for cold tolerance in bacteria, plants and fish, the primary role of HUFAs in mammals is cell signaling. These enzymes are described as front-end desaturases because they introduce a double bond between the pre-exiting double bond and the carboxyl (front) end of the fatty acid. Various substrates are involved, with both acyl-coenzyme A (CoA) and acyl-lipid desaturases present in this CD. Acyl-lipid desaturases are localized in the membranes of cyanobacterial thylakoid, plant endoplasmic reticulum (ER), and plastid; and acyl-CoA desaturases are present in ER membrane. ER-bound plant acyl-lipid desaturases and acyl-CoA desaturases require cytochrome b5 as an electron donor. Most of the eukaryotic desaturase domains have an adjacent N-terminal cytochrome b5-like domain. This domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain the residues: HXXXH, HXX(X)HH, and Q/HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homolog, stearoyl CoA desaturase.	1.42921e-67
NZ_CP041168.1|WP_141203684.1|1333730_1334897_-|xylose-isomerase	gnl|CDD|237170	PRK12677, PRK12677, xylose isomerase; Provisional.	0
NZ_CP041168.1|WP_141203689.1|1341125_1342649_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143434	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like. Included in this CD is the NAD+-dependent, acetaldehyde dehydrogenase II (AcDHII, AcoD, EC=1.2.1.3) from Ralstonia (Alcaligenes) eutrophus H16 involved in the catabolism of acetoin and ethanol, and similar proteins, such as, the dimeric dihydrolipoamide dehydrogenase of the acetoin dehydrogenase enzyme system of Klebsiella pneumonia. Also included are sequences similar to the NAD+-dependent chloroacetaldehyde dehydrogenases (AldA and AldB) of Xanthobacter autotrophicus GJ10 which are involved in the degradation of 1,2-dichloroethane. These proteins apparently require RpoN factors for expression.	0
NZ_CP041168.1|WP_141203675.1|1320944_1321544_+|methyltransferase-domain-containing-protein	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	4.83426e-22
NZ_CP041168.1|WP_141203685.1|1335043_1336489_+|xylulokinase	gnl|CDD|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	0
NZ_CP041168.1|WP_141203677.1|1322453_1323011_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	8.12846e-16
NZ_CP041168.1|WP_141203679.1|1323625_1325053_-|monooxygenase	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	2.31329e-12
NZ_CP041168.1|WP_141203687.1|1339091_1339691_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	5.49155e-41
NZ_CP041168.1|WP_141203674.1|1320018_1320792_-|hypothetical-protein	gnl|CDD|225837	COG3300, COG3300, MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms].	2.40352e-37
NZ_CP041168.1|WP_141203690.1|1344975_1345575_-|hypothetical-protein	gnl|CDD|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	1.35971e-17
NZ_CP041168.1|WP_141203676.1|1321590_1322346_-|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.67093e-19
NZ_CP041168.1|WP_141203678.1|1323089_1323575_+|VOC-family-protein	gnl|CDD|319910	cd07246, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.35279e-36
NZ_CP041168.1|WP_141203686.1|1338049_1339063_+|acetamidase	gnl|CDD|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	3.14225e-57
NZ_CP041168.1|WP_141203688.1|1339788_1341069_+|GAF-domain-containing-protein	gnl|CDD|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	5.50358e-27
NZ_CP041168.1|WP_141203683.1|1331265_1332540_+|SWF-or-SNF-family-helicase	gnl|CDD|226729	COG4279, COG4279, Uncharacterized conserved protein [Function unknown].	1.09151e-27
NZ_CP041168.1|WP_141209114.1|1336640_1337801_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	2.13285e-49

Protein sequences

>NZ_CP041168.1|WP_141203682.1|1327019_1328078_-|acyl-CoA-desaturase
MPQSTATLVPHPRGTSGSPPGPSEFTALLRAVKNRGLLERRHGWYARTIAVNALALAGLVTAVALSGDTWLTLLLAPLLAVFSARTAFIGHDAGHAQITGDKATGRVIGLVHGNLLLGMSYSWWNHKHNRHHANPNHIDKDPDVAADVLVFTGEQAKLRTGFRRWLTRRQAWLFFPLTLLEGIALKIQGFRDLRRQAPGERAVEGALLVTHVVAYATLLLTVMSPGKALAFAAIHQALFGLHLGMSFAPNHKGMEMPDPDGESWGHLRRQVLTSRNIRGGAVTDWFLGGLNYQVEHHLFPSMPRPHLRLAQPLVRAHCRDLGIPYTETGLVDSYRQALRHMHDVGEPLRADH
>NZ_CP041168.1|WP_020137233.1|1326716_1326899_-|hypothetical-protein
MSKNAKIAAGGVAVGLLLLIWLPWWAALLIVLGVPAAAYLTLDPSQRRRLRRVTRKELGR
>NZ_CP041168.1|WP_141203681.1|1325670_1326663_+|hypothetical-protein
MAGTDEDAVAAAEDALYVLTAVLLTPAKFPSVLGDDYPEACAALGLAPLADGYGLVIGQDGAGARWTVVIDDVSLVAVAIASWDCGMEYELSPEEHTVVAALPGWPLAVAVAAPGVPAPHDPDADAAYGPVLAPPDTTTWGSAQRRLGADEIALQWSMWREQIDDSAFPSPSGASAASEKTSAGQISGEKAADQGPLEGNSSPGTSSNGQAVDGSIAESGPSDGAGSVTETSGGAGKTAGKGHSGVRRVLAEARAYIESPPPLGRVRSSFASGDSRTLRADGPGWSLVARTDDIAFVLLDDEPGEVLPVGRGPELPGLLAALDKLAVRPS
>NZ_CP041168.1|WP_141203680.1|1325238_1325535_+|hypothetical-protein
MWGRIRKSGTRLVNAMRIEEQPEGETRAHNLFEAAAAYVSACAEDDQERLEEAAAWVSPEALSFGVNELACRAVIALARERDESPREVARALLGLPAA
>NZ_CP041168.1|WP_141203679.1|1323625_1325053_-|monooxygenase
MNSAGQKGRWGEGDGRGERHAVVVGGSLAGLLAAHALAGHADRVTVVERDRFPDGPVPRPGVPQGRHPHVLLKGGQQALEALLPGFLDELREAGAPRVGMPSDMVMWQNGRWFRRYPATTHIYTGSRAQLEELVRRRVLADPVISVVDGTDVVGLLGDAARVRGVLLRERSGDAHAEARPLEADLVVDASGGGTRASRWLTAIGAEAAPEETIDTGLAYASRVYRGPRGVLDGGTLGYYVYPGPDQVHGGGALPLEDGSHLVIVSGLRGDEPPTGDEEFVAYTKRLAHPLLDRWLAEAEPLSTAFGYRRTANVRRRHDLPGRPAGFLATGDALCTFNPIYGQGMAVAAMSAVALRDALSDPRRTPTTRRVQQALLAASRQAWDISAGADRKMPGAVGSALAGGPADRVAGWYLRRVQERAPGDPVVGRAFRAVLTLSAPVGALFAPPVARAVLFGQVPPTPAEPPTVPEEPRSRT
>NZ_CP041168.1|WP_141203678.1|1323089_1323575_+|VOC-family-protein
MTERSARAVIPDRYRHAVIPHIMVGDAAAAIDFYQRAFGAREDFRLDAPGGGILHAEITVGQSVLMLGDATVDEAESGAFASPASLGGGTSVALHVFVPDVDSLAKRAEAAGAEILQPPQDTFHGDRTVILKDPSGHLWVFLTHVEDLSEEELQRRLTNAR
>NZ_CP041168.1|WP_141203677.1|1322453_1323011_+|helix-turn-helix-transcriptional-regulator
MLETAILGFLYDTPLHGYELRKRISALAGHVRPVAESTLYPAIKRLETAGLLARATEPGAVAAPRHVLTLTDEGRRELRRRLAEPVRRDITDENRWFTVLAFLRHLDDAGAQAAVLRRRLAFLEEPASFFYEGDRPLSAEELDDPFRRGVLVIARATSRAELGWLRETIAALDSGSGAAPGHVRA
>NZ_CP041168.1|WP_141203676.1|1321590_1322346_-|alpha/beta-fold-hydrolase
MKQAEFDGRGSRIRWTETPGAEPARVYVHGLGAVSAVYHAHIAARPELAGRRSLFVDLPGHGASDRPQDFGYTLRDHADALAVVLEAAGLTGVELIAHSMGGSVALVLAHRRPELVSRLVLTEANLDPSPPSSAGSTWIDAYAEDDFVAGGHARVLEKAGPLWAATMRLADPRALHRSAAGLRRGSVPMMRAILEALPMERVYLQGELTGELEGREGLEAAGVRVLTVPGAGHNVMFENPDAFVAAVAGTG
>NZ_CP041168.1|WP_141203675.1|1320944_1321544_+|methyltransferase-domain-containing-protein
MSDDHTHVQEFFSARAADWDRRFPDDGPAYAAAVAELGLREGDRVLDAGCGTGRALTPLRAAVGPTGVVVGADLTPAMLEAAVGAGRDRDGRLLLADVTALPLRSRSLDAVFGAGLISHLPEPAENLRELARVVRPGGVLALFHPIGRAALAARQGRQITPEDLRAEANLRPLLAGSGWHLTSYTDEAARFLALAVRES
>NZ_CP041168.1|WP_141203674.1|1320018_1320792_-|hypothetical-protein
MGHLDHAALGWLTPTLSYVMACIGAALGLRCTVRALGATGRSRRNWLITAASAIGTGIWTMHFVAMLGFSVSGTDIRYDVPLTIASLLVAMVVVSAGVFAVGYGRDRIRALFLGGLTTGLGVASMHYLGMAAVRLHGHIDYDPALVGLSVLIAVVAATAALWAALNIKSPVAVTIASLIMGAAVSSMHYTGMFAVSVRVAPSGVLLPGATAMQFIFPLAVGLGSYLFLTSAFVALSPTTGEREATASAQRAAETVPS
>NZ_CP041168.1|WP_141203683.1|1331265_1332540_+|SWF-or-SNF-family-helicase
MTGHDTDTERTFAALPPAQGRGFAQTWWGQAWLRALEDAALDSGQVKTGRRLARAGAVGAVSVRAGRITALVLDRDRTAHRADVLLAELSAEQWDRFLDLAVERSGHVAALLDREMPTHLVEDAASAGIDLLPGLGDLEPECDCGAWDHCGHTAALCYQMARLVDQDPFVLLLMRGRGEQSVLDALQARTAAPAEEASAPEGVDAAEAYAAGDILPPLPAPPVPPVVPGLPPTLDTEVPPAPGVDPVALRHLAARTAVEAHRLLTEALRPPSDQHAAGTEPTAAQDAVRLAVDAPDDTVTDRLAEGSGRDPQSLAVATRAWEFGGAAALAVLEEEWTPDEEGEVHARARAALHSAWDEDERPALRAVGNRWTVADAPAQIRLGRDGRWWPYRREQGRWVPAGPAALDPATALASAGPASVESRR
>NZ_CP041168.1|WP_141209113.1|1333043_1333274_-|hypothetical-protein
MAAVAVIAVIFMASGSDDSQDKNPAPQTSTNGSPEPSFSLPTRLPSELPSELPSQFPSELPSEFPSDLESLLPSFG
>NZ_CP041168.1|WP_141203684.1|1333730_1334897_-|xylose-isomerase
MNYQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVETVQRLAELGAHGVTFHDDDLIPFGSSDSERENHIKRFREALDATGMKVPMATTNLFTHPVFKDGAFTANDRDVRRYALRKTIRNIDLAVELGAETYVAWGGREGAESGAAKDVRVALDRMKEAFDLLGEYVTEQGYDLKFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRAAFWLVDLLESAGYAGPKHFDFKPPRTEDLDGVWASAAGCMRNYLILKERATAFRADPRVQEALRAARLDELAQQTAADGLKSLLADRTAFEDFDVEAAAARGMAFEQLDQLAMDHLLGARG
>NZ_CP041168.1|WP_141203685.1|1335043_1336489_+|xylulokinase
MSAAEGPLVVGVDTSTQSTKALVVDAATGRVVARGQAPHTVSSGAGRESDPRQWWDALSEALRQCGDAAREAAAVSIGGQQHGLVTLDAQGEPVRPAMLWNDVRSAPQARRLIDELGGPKAWAERTGSVPGASFTITKWAWLAEHEPEALRATKAVRLPHDYLTGRLTGEGTTDRGDASGTGWWASATESYDSEILAHVGLDPALLPRVVRPGEVAGTVRDGHDLPFSKGTLVAPGTGDNAAAALGLGLRPGTPVMSLGTSGTVYAVSKRRPTDPTGTVAGFADAHGDWLPLACTLNCTLAVDRVAALLNLDREAVEPVSGVTLLPYLDGERTPNLPNASGLLHGLRHDTTGGQLLQAAYDGAVQALLGALDLVLDADADRSTPLLLIGGGAQGTAWQQTVRRLSGRPVQVPEAKELVALGAAAQAAGLLTGEDPGAVARRWNTAAGPVLEAVERDDETLARIAGVLSDAAPLLERGTSGE
>NZ_CP041168.1|WP_141209114.1|1336640_1337801_+|ROK-family-protein
MPDTQQGMRRRNLARVMHAVSAEGPLSRAAVASRIGLTRAAVSTLVDELIRSGLLEELGPERPGRVGRPGSALAVSGRGPAGIGAEIGVDHLAVCAVDLRGQTRAQVVRYGANRGRAPEPVIAELSSLVRQVVAEAEGEGLWPAGLAVAVPGLVARDARTVVRAPNLDWHDTDLGALLPEDFPLTVGNEANFGALAELWLGDGTPHDFLHVSAEIGIGAALVVDGQLLRGTRGFAGELGHVPVRPDGPRCPCGGRGCLEQYAGEEAVLRAAGLEQGEDRVGLLAQHAADGDEDVRDALREAGEALGIALTGAVNLLDPDGVVLGGALAGLAPWLLPSLRDELARRTAGQSCPVSVSRLGSQGPLLGAAHSVVRAVLDDPSVVGERA
>NZ_CP041168.1|WP_141203686.1|1338049_1339063_+|acetamidase
MSDPRILTVRPEPGDYAWTFGGAPPVARIRPGTVLDLYTEDCFAGRVRSEKDLVSEVCEFPFLNPQTGPFHIEGAEPGDTVAVHFVSVEPARDWAASTTVPLFGALTSTHTTATLQPPLPETVWIWQLDRTRRTALFRAHDSDIEIELPMDPMHGTVGVAPANLEVRSALVPDAHGGNMDTPEMRAGVTCYLGVNVEGALLSLGDGHARQGEGETCGVAVECAMNTVVIVELLKGLATPWPRIESDTHIISTGSARPLEDAFRISQLDLVQWLVRDYGFSELDAYQFATQAVESPLANVCDTNYTCVAKIRKEWLPARETHRGVHHRLRETAAAFRG
>NZ_CP041168.1|WP_141203687.1|1339091_1339691_+|N-acetylmuramoyl-L-alanine-amidase
MERARPQFDRRRLLKGALLAAVPYTLLPETRAGAAPQTGDYPLAEWQPATSSNFTESDRPWSYRVNLVVVHVTQTSYTEALDIFRNPAKQVSAHYVVRSADGHIAQCVREADVAWHAGNWDYNTRSIGIEHEGWVDKPAYFTDALYEESAKLTAGICEKYGIPRDRAHIIGHYEVPGSDHTDPGPSWDWTRYMRMVEAM
>NZ_CP041168.1|WP_141203688.1|1339788_1341069_+|GAF-domain-containing-protein
MSDPWVALEAGADPAERVRVLLRAHETFTEAGTVQRPVRPVVADSWRRSARAGVGPDGTANVELSDGDLGVYRAEHPLARVMPLFRELMGTFASDGEHLLAVCDEHGRLLWVEGHATTRRKAGRMNFVPGARWSETAVGTNAPGTAVAVDRPVQVFAAEHFIRRVQPWTCAAAPVHDPRTGRVLGAVDITGGDGLAHPHSLGFVQAVARAAESQLALLLPPETAADTPELSALGRDEAVFASAGRRIRLSRRHSEILVLLSRHPEGLSGDELLCALYEDESVTPVTLRAELARLRRVLGPGLLASRPYRLTVPVESDVAAVERRLESGAVTGAARGYTGPLLPASRAPAVARLRRLIADGLRTALIARRDPDLLADWAHAPWGEDDLDVWRALAAVRPTASVRARLAALESELAAPTATWLQRPRF
>NZ_CP041168.1|WP_141203689.1|1341125_1342649_+|aldehyde-dehydrogenase-family-protein
MTRYAAPGTEGAIVSYQARYDHFIGGEYVPPARGQYFENPSPVNGQPFTEVARGTAEDVERALDAAHAAAPGWGRTSVTERSDILLKIADRMEANLEKLAVAESWENGKPVRETLAADIPLAIDHFRYFAGAIRAQEGSLGEVDDDTVAYHFHEPLGVVAQIIPWNFPILMATWKLAPALATGNAVVIKPAEQTPASIHYWMSLIADLLPPGVLNIVNGFGVEAGKPLASSPRVAKVAFTGETTTGRLIMQYASENIKPVTLELGGKSPNIFFDDVWARDDDFRDKALEGFTMFALNQGEVCTCPSRALIQSGHYSEFLEAAVARTELIKPGHPLDTDTMIGAQASNDQLEKILSYLDVGRQEGARVLTGGERIEYDGELKGGYYVQPTIFEGDNRMRIFQEEIFGPVVSVTSFADFDDALKIANDTLYGLGAGVWTRDINTAYRAGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKNVLVSYSPKKLGFF
>NZ_CP041168.1|WP_141203690.1|1344975_1345575_-|hypothetical-protein
MALAHQHDRRVMVPWRSMRVTMILNVTCNDRRWFAETDTEVSTVVTEVLGSLQGWNKRGEHWHPGTVAWFSWSDRRHMGDADMPNNFLVVSLNRESGYGGLIWFVNAGYPGPESDEVLDNIWVSDNPNPPDFDTEVVSNPGEPYWFDPRSTLPIEEIEAAVHEFCRVRTGIRPACVQWTLGEVSGRRADREPETDLPPY

Crispr_ID: NZ_CP041168_2

• CRISPR_ID: NZ_CP041168_2
• CRISPR_location: 1593034-1593115
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_2

Consensus_repeat	Method
GGTGCGCAGGCGCTCCAGGTTCAGCA	CRISPRCasFinder

spacers of NZ_CP041168_2

>2.1|1593060|30|NZ_CP041168|CRISPRCasFinder
TGCGGGCCACCCTTCCACGCGCGGGTGCGA

CRISPR arrays and Neighbor proteins around NZ_CP041168_2

CRISPR arrays

The CRISPR arrays of NZ_CP041168_2

>merge|NZ_CP041168|2|1593034-1593115|CRISPRCasFinder
GGTGCGCAGGCGCTCCAGGTTCAGCATGCGGGCCACCCTTCCACGCGCGGGTGCGAGGTGCGCGGGCGCTCCAGGTTCAGCA

>NZ_CP041168|2|2|1593034-1593115|CRISPRCasFinder
GGTGCGCAGGCGCTCCAGGTTCAGCA	TGCGGGCCACCCTTCCACGCGCGGGTGCGA
GGTGCGCGGGCGCTCCAGGTTCAGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141203849.1|1584795_1585479_-|uracil-DNA-glycosylase	unknown	unknown	gnl|CDD|235376
NZ_CP041168.1|WP_141203864.1|1598831_1599020_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_062026143.1|1599147_1599576_+|polyketide-cyclase	unknown	unknown	gnl|CDD|176864
NZ_CP041168.1|WP_141203852.1|1589067_1589517_-|DUF3037-domain-containing-protein	unknown	unknown	gnl|CDD|378608
NZ_CP041168.1|WP_141203863.1|1598030_1598633_-|peptidase	unknown	unknown	unknown
NZ_CP041168.1|WP_141203858.1|1593121_1594471_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|185378
NZ_CP041168.1|WP_141203865.1|1600506_1601403_-|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl|CDD|369561
NZ_CP041168.1|WP_141203856.1|1591688_1592156_+|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|334450
NZ_CP041168.1|WP_141203850.1|1585624_1587205_-|peptide-binding-protein	unknown	unknown	gnl|CDD|173884
NZ_CP041168.1|WP_141203853.1|1589513_1590278_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141203854.1|1590432_1590909_+|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl|CDD|239550
NZ_CP041168.1|WP_141203855.1|1590895_1591552_-|isochorismatase-family-protein	unknown	unknown	gnl|CDD|376404
NZ_CP041168.1|WP_020140547.1|1588173_1588935_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187594
NZ_CP041168.1|WP_028810074.1|1599702_1600332_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP041168.1|WP_141203859.1|1594506_1595190_+|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|378988
NZ_CP041168.1|WP_141203860.1|1595189_1595822_+|FMN-binding-negative-transcriptional-regulator	unknown	unknown	gnl|CDD|377290
NZ_CP041168.1|WP_141203861.1|1595825_1596737_-|EamA-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP041168.1|WP_141203862.1|1596927_1597926_-|EamA-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP041168.1|WP_141203848.1|1584079_1584598_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141203851.1|1587396_1588161_-|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|235975

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141203849.1|1584795_1585479_-|uracil-DNA-glycosylase	gnl|CDD|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	1.3408e-143
NZ_CP041168.1|WP_141203861.1|1595825_1596737_-|EamA-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	4.28215e-17
NZ_CP041168.1|WP_141203859.1|1594506_1595190_+|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	1.71227e-52
NZ_CP041168.1|WP_141203858.1|1593121_1594471_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	1.14819e-112
NZ_CP041168.1|WP_141203865.1|1600506_1601403_-|alpha/beta-hydrolase-fold-domain-containing-protein	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.45724e-75
NZ_CP041168.1|WP_141203856.1|1591688_1592156_+|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	1.17008e-13
NZ_CP041168.1|WP_141203850.1|1585624_1587205_-|peptide-binding-protein	gnl|CDD|173884	cd08519, PBP2_NikA_DppA_OppA_like_20, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP041168.1|WP_062026143.1|1599147_1599576_+|polyketide-cyclase	gnl|CDD|176864	cd07822, SRPBCC_4, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	8.87265e-17
NZ_CP041168.1|WP_141203855.1|1590895_1591552_-|isochorismatase-family-protein	gnl|CDD|376404	pfam00857, Isochorismatase, Isochorismatase family. This family are hydrolase enzymes.	4.38898e-25
NZ_CP041168.1|WP_141203854.1|1590432_1590909_+|Rieske-2Fe-2S-domain-containing-protein	gnl|CDD|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	4.69707e-25
NZ_CP041168.1|WP_020140547.1|1588173_1588935_-|SDR-family-oxidoreductase	gnl|CDD|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.81271e-98
NZ_CP041168.1|WP_141203860.1|1595189_1595822_+|FMN-binding-negative-transcriptional-regulator	gnl|CDD|377290	pfam04299, FMN_bind_2, Putative FMN-binding domain. In Bacillus subtilis, family member PAI 2/ORF-2 was found to be essential for growth. The SUPERFAMILY database finds that this domain is related to FMN-binding domains, suggesting this protein is also FMN-binding.	9.53818e-40
NZ_CP041168.1|WP_028810074.1|1599702_1600332_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	4.44697e-22
NZ_CP041168.1|WP_141203852.1|1589067_1589517_-|DUF3037-domain-containing-protein	gnl|CDD|378608	pfam11236, DUF3037, Protein of unknown function (DUF3037). This bacterial family of proteins has no known function.	1.92889e-57
NZ_CP041168.1|WP_141203862.1|1596927_1597926_-|EamA-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	5.4164e-21
NZ_CP041168.1|WP_141203851.1|1587396_1588161_-|glucose-1-dehydrogenase	gnl|CDD|235975	PRK07231, FabG-like, SDR family oxidoreductase.	1.37063e-114

Protein sequences

>NZ_CP041168.1|WP_141203856.1|1591688_1592156_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MTVTQRRGRKIMMTPGELDEFLTSQRTCRVATVSGGGAPHVSTLWFAWDGTSMWLYSVVRSKRWTDLRRDPRIAIVVDTGEEYDELRGVELSGTVDFVGEAPRTGELCAELDVPETLFARKNFRLEEMPHDGRHAWIRLTPEKIVSWDFRKLGSA
>NZ_CP041168.1|WP_141203855.1|1590895_1591552_-|isochorismatase-family-protein
MPSYGQLSELLAPGTTVLLTVECQQGVVGPDSALPELAREARKSGALANVARLVAAAHESGVQVIHAIAERRPDGRGANRNARLFHAAERLPVQQLSGTSAVRVAPPIEVSEEDFVVRRLHGLSPIQGTEVDALLRNLGCRTLVVTGVSANVAVPNAVFDAVNRGYTVVVPSDAVAGVPSDYTPVMIRHTLALVATIATTDEVLGALGRPRRPRVRPA
>NZ_CP041168.1|WP_141203854.1|1590432_1590909_+|Rieske-2Fe-2S-domain-containing-protein
MTSELPQSVPAPARRTVVAAVGAAGLAVALTACGSDGDSSGSSTSQADANAGGGGASSSSGSGGTALAKTSDIPEGGGTIFKDQGVVVTQPTAGTFKAFSSKCTHQGCAVGSVADGVIVCPCHNSHFSVEDGSVKKGPATQPLPAAQINVSGDSITLA
>NZ_CP041168.1|WP_141203853.1|1589513_1590278_-|hypothetical-protein
MLKEAIATRYITPLREGGSLPGLVEADDRGTYVIKFTGAGQGRKTLVAEVVAGELARRLGFRVPRLLTLDLDPDLGLGEPDERVQELLRSSGGTNLGMDFLSGALGFDPLAFPVDPEEAGRIVWFDALVNNVDRSWRNPNLLWWRSEVWLIDHGATMIWHHNWPGAEKSAARPYDASDHVLRPFAPDVAAAAAALAPQLTEDLLAEVTGEIPDAWLADEPGFDTPDDLRRAYARPLLQRAAAVHERITGIEGDK
>NZ_CP041168.1|WP_141203852.1|1589067_1589517_-|DUF3037-domain-containing-protein
MSERHIHMAGSVVERHVIKGGRVSERDVFEYVLLKVVPRVERGECINAGVLVYCRAKAYVGVRTHLDEDRLRALDPAADVSGVRAALQAVEAVCAGGDAAGPAARDDAGRRFRWLVAPRSTVVQPGPVHTGLTLDPAAEAERLLDLLVR
>NZ_CP041168.1|WP_020140547.1|1588173_1588935_-|SDR-family-oxidoreductase
MSTTEQRVAVVTGAARGIGAATAVRLAAEGRAVAVIDLDEAACKDTVEKITAAGGKAIAVGADVSDEAQVEAAVARVVAELGAPTILVNNAGVLRDNLLFKMSVSDWDTVLNVHLRGSFLMTKAVQKHMVDAGFGRVVNLSSSSALGNRGQANYSAAKAGLQGFTKTLAIELGKFGITANAVAPGFIATDMTAATAARVGMGFEEFKAAAATQIPVARVGEPDDIANAIAFFTGEAAGFVSGQVLYVAGGPLD
>NZ_CP041168.1|WP_141203851.1|1587396_1588161_-|glucose-1-dehydrogenase
MTSQLPELSGKVALITGASRGIGYGVAEALVARGDRVVITGRNEDALKEAVEQLGSDRAVGVAGKAHDEAHQAVAVERAMEAFGRVDFLVNNAGTNPVFGPIADLDLNVARKVFETNVISALGFAQKTWHAWQKDNGGAIVNIASVAGIAPSPFIAAYGVSKAAMINLTQQLAHEFAPKVRVNAIAPAVVKTKFAQALYEGREAEAAASYPLARLGVPSDIGGAAAFLTSEQSDWVTGQTLVVDGGIFLNAGVG
>NZ_CP041168.1|WP_141203850.1|1585624_1587205_-|peptide-binding-protein
MFMRNRYLPPFAALVSLSTVAGCGVFSSGSSDDGKAIVVGTTSAPATLDPAASWDNSWELFRNVYQTLLNYSPGGSDPEPDAAEHCEFTDTSSTVYSCTLREGLKFSDGHPLNAQAVKYSIDRIKRINVNGGPAGLLGTLSRVQTKGDREIVFHLSQPDATFPLVLTTPAMSIVDPEEYSATAIRKDGKINGSGPYRLDSYQEGEKAELVRNDNYKGIADLQNNAVTIRYFSRSDEMVKALKDKQIAVVYRGLGASDTVDIEVNQRKEGLQLVENPTTEISYLVFNPKDPWSAKPAVRKAVAQVVDRPALVHYVYKDTVEPLYSMVPAGLTGHTTGFFDDFGDPSVPKARKILREAGITERVPLTLWYTSDRYGSTTKPAFEELKKQLESSGLFRITLKSRPWKTYVQGYQNGEYPVFGRGWFPDFHDADNFISPFVGKQNALGTPYDAPEITGKLLPQSRAESDRGAVGPQIEEAQQVFVNDARLVPLWQGKQYVAASEEIAGLEKVIDPATMMTMWELYWKTSW
>NZ_CP041168.1|WP_141203849.1|1584795_1585479_-|uracil-DNA-glycosylase
MTDIAMLPESWRGVLGDELQQPYFKELTEFVEDERAKGPVYPPREEVFAALDATPYDRVKVLILGQDPYHGEGQGHGLCFSVRPGVKTPPSLRNIYKEMKEELGTEIPDNGYLMPWAQQGVLLLNAVLTVRAGEANSHKGKGWEKFTDAVIRAVAERPDPAVFVLWGNYAQKKLPLIDESRHVVVKGAHPSPLSAKKFFGSRPFTRINEAVAAQGHEPIDWTIPNLG
>NZ_CP041168.1|WP_141203848.1|1584079_1584598_-|hypothetical-protein
MTERQEQAVPDAVMTRIGQVVMLCHAGDREEARHRYLALWAEIGEDGDPLHRCTLAHYMADAQDDPCDELAWDLRALTAAEELTDDRLVRHEGALAVRALYPSLHLNLAADYVRLGRTDAARSHLRRARRASAELGEDTYSDGVRAAISRLELRLGEGGTAGDGWGPPRQRP
>NZ_CP041168.1|WP_141203858.1|1593121_1594471_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MLGGYRIEGRRAAEIAASVERAVGAGELEPGQPLPPMRELAGQLGVNPNTVAAAYRSLRERGVIETAGRRGSRVRSKPATTGRESIRVEVPEGVRDVANGNPDPALLPPLGPAFAAAAEQGDREPVLYGDATVDPELARLARGALDADGVPAGPLAVASGSLDVIERVLAAHLKPGDTVAVEDPGWGSLLDLVPALGLRVAPVGVDDEGPLAEDVRRALESGARALIVTDRAQNPTGASVTAPRARALRAVLAGHPDTLLIEDDHGHGIVDLPLHPLAGVTRHWAFVRSVAKAYGPDLRLALLTGDEITVDRVHGRHRLGPGWVSRITQRAVVNLWADGVLDTAKPAAAYRERRDQLIEALAARGVEAHGRSGLNVWIPVQDETGAVARLLHAGWAVAPGARFRMSAPQGIRVTVATLKADEVAPLADAVAKAVGPAPGHAHQHLRVER
>NZ_CP041168.1|WP_141203859.1|1594506_1595190_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MQGTTATTPEPTAYAPTDRTVPTRSAERASYDRDLVHSILDEGYVCHLGFVRDGAPVVLPTLYGRVGERLYVHGSTGSRPLRMTGQADPGLPVCLTVTHVDALILARSAFHHSINYRSVVVHGLAHDVTDPKEKRLALDALVDHVVPGRAQDSRPANKKELAATAVIRLDLDEVSAKLRTGGVNDEPEDLALPHWAGVLPLRKGYGSPVADGDLAPGTEVPGYLTAL
>NZ_CP041168.1|WP_141203860.1|1595189_1595822_+|FMN-binding-negative-transcriptional-regulator
MLIHPWDAAASDAEWQQWLAVHDFGQLAVNGPAGEPPFVQPLHFFYDPGRGEAVTHLARPNPLWSALEANPEVVLSVVDDYAYIPGPWQADPDGPAAHGTPTSFYAAVQLRCRAHVVDDPAEKAALLNRQVGHFQPEGGSAEVAVGEVPYGRMLSGIRGLRLEVTEVRAKFKYAGKRTEQVRERIAEGLADRGGPGDAAAREHLLRRRRG
>NZ_CP041168.1|WP_141203861.1|1595825_1596737_-|EamA-family-transporter
MSHASSGLPVGRGLVYLIIAGTTWGTAGAVASLVYRTSDLGPAALSFWRCASGLAVLLAVRLARPRARTTVPEPLVRRALRVGGSGVALAVFQTAYFAAVRSTGLAVATVVTLGAGPVLSALGARLVLGERLGRSGAVAVVGALAGLGVLTLGGTGASVRPLGVLLGLLSAAGCCVMTLITRAAEAESTGTSAGVFAVTSLCLLPFAVAGGLVPHTGHPALLLGLLAYLATVPTALAYGLYFAAAAVVRPTTVSVVMLLEPVSAAVLAVLLFGEHLTLTTLAGTLLMLGAVAGLAVTEGRVRA
>NZ_CP041168.1|WP_141203862.1|1596927_1597926_-|EamA-family-transporter
MHTSESSRAGDGKGVGLGLALVSALAFGGSGVAAKPLIEAGLDPLHVVWLRVAGAALVMLPLAVRHRALLRSRPALLAGFGLLGVAGVQAFYFASISRIPVGVALLVEYLAPAMVLGWVRFVQRRPVTRAAALGVVLAVGGLACVVEVWSGLSFDALGLLLALGAACCQVGYFVLSDQGSDSGRQAPDPLGVIAYGLLVGTAVLTVVARPWTMDFSVLTHRADMNGTPVAAGLLLGWIVLVATVLAYVTGVVSVRRLSPAIAGVVACLEAVVATVLAWVLLGEHLSAPQIVGGAVVLLGAFIAQSSTPAKGTLEPVAGGGAETRLSARENAA
>NZ_CP041168.1|WP_141203863.1|1598030_1598633_-|peptidase
MHPRIPRQSARDQDRPPQVAPDGDATLSAELAAVVSGARRRALRDGDRQIDTAHLLHSLLDADAEACAVFEDEPHLPRLLGYLVQRSIGYGLRWQGTVEDSGAVPVVTAPGTLGADPAAAAAEGFSPLAAEAMQHARVRAGHRDGGPARGVDLLAAILVDPGSRAVEVLARAGIDAGEVRARLDGLMPGDLWGRSRRGNR
>NZ_CP041168.1|WP_141203864.1|1598831_1599020_+|hypothetical-protein
MESGSWLVALPAVDGREYVYRVYAPEDARPADLFWQAWHCHDESAHPRAWDLFDAATIRPVC
>NZ_CP041168.1|WP_062026143.1|1599147_1599576_+|polyketide-cyclase
MAEISAEALVQAPADKVWAQLTDWSSYGEWNATHTSFPKGGPAVLEVGATFQENMKLMGFPAEVEWTVDQVEPARLLAIRGKGPMAVSVATRYTLTPDGDATDVRIDGEFTGAAVSLMAGKLKDSGTAALNESLRKLAGLVE
>NZ_CP041168.1|WP_028810074.1|1599702_1600332_-|helix-turn-helix-transcriptional-regulator
MRSHGFERGHGGAGRQGRGGFEGRRGAFGPFGPGGPGGPGGPFGGPGFGPGPWGPRGRGGPRGRARRGDVRASILALLKDRPMHGYEMIQEIAERSGGAWKPSPGSVYPTLQLLEDEGLIASESEGGKKLFSLTEAGRTAADEGPDAPWEEASRGIDFEALGEIRQAGFGLMEAFGQVWKTGNKEQRDKAVAVINEARKKLYLILADED
>NZ_CP041168.1|WP_141203865.1|1600506_1601403_-|alpha/beta-hydrolase-fold-domain-containing-protein
MPFSPRIQARGIQLLLGRVMARVHKDLRFTDIPAYTETLRVRTGAGPVKCTVYRPTGTAADTPAPVYVNFHGGGFVVARPEQDDHLCRRIAATAGCVVVNVDYAVAPRHPYPAAVTQAYDVTAWIAGNGAAGGWDGSRLAVGGHSAGGNLAAAVCRLARERGTFTPRLQIIDSAPLDQRADPATKRSLVAKPLLSPQVMRIFTAAYVPDPADRAHPLVSPALADDLSGLPPALVITAENDRLRDEGDAYAKALEAAGVPVTHRVFEGVDHYFTHAGPASSGRAAIDLMASSLRVALGS

Crispr_ID: NZ_CP041168_3

• CRISPR_ID: NZ_CP041168_3
• CRISPR_location: 2479963-2480055
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_3

Consensus_repeat	Method
GCCCGCCCATGACCGACATCGCC	CRISPRCasFinder

spacers of NZ_CP041168_3

>3.1|2479986|47|NZ_CP041168|CRISPRCasFinder
CACCGGGAGGCTGCCCGCCCATGACCGACATCGCCCACCCGGAAGCC

CRISPR arrays and Neighbor proteins around NZ_CP041168_3

CRISPR arrays

The CRISPR arrays of NZ_CP041168_3

>merge|NZ_CP041168|3|2479963-2480055|CRISPRCasFinder
GCCCGCCCATGACCGACATCGCCCACCGGGAGGCTGCCCGCCCATGACCGACATCGCCCACCCGGAAGCCGCCCGCCCATGACCCACATCGCC

>NZ_CP041168|3|3|2479963-2480055|CRISPRCasFinder
GCCCGCCCATGACCGACATCGCC	CACCGGGAGGCTGCCCGCCCATGACCGACATCGCCCACCCGGAAGCC
GCCCGCCCATGACCCACATCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141204464.1|2466601_2467519_+|chitosanase	unknown	unknown	gnl|CDD|376538
NZ_CP041168.1|WP_141204469.1|2477467_2478634_+|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NZ_CP041168.1|WP_141204472.1|2480930_2482121_+|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_CP041168.1|WP_141204480.1|2488827_2489076_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141204465.1|2467669_2469130_-|glutamate-synthase-small-subunit	unknown	unknown	gnl|CDD|237213
NZ_CP041168.1|WP_141204475.1|2484086_2484860_-|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|372611
NZ_CP041168.1|WP_141204473.1|2482117_2482945_+|CoA-ester-lyase	unknown	unknown	gnl|CDD|225184
NZ_CP041168.1|WP_141204468.1|2476094_2477459_+|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NZ_CP041168.1|WP_141204476.1|2484962_2485781_-|tryptophan-synthase-subunit-alpha	unknown	unknown	gnl|CDD|237285
NZ_CP041168.1|WP_141204466.1|2469122_2473715_-|glutamate-synthase-large-subunit	unknown	unknown	gnl|CDD|236968
NZ_CP041168.1|WP_141204462.1|2464852_2465575_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|378410
NZ_CP041168.1|WP_078616718.1|2487142_2487340_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141204467.1|2475081_2476098_+|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NZ_CP041168.1|WP_062024641.1|2474093_2474825_-|hypothetical-protein	unknown	unknown	gnl|CDD|153124
NZ_CP041168.1|WP_141204477.1|2485777_2487064_-|tryptophan-synthase-subunit-beta	unknown	unknown	gnl|CDD|235288
NZ_CP041168.1|WP_141204479.1|2488308_2488749_-|DUF2752-domain-containing-protein	unknown	unknown	gnl|CDD|378499
NZ_CP041168.1|WP_141204478.1|2487361_2488171_-|indole-3-glycerol-phosphate-synthase-TrpC	unknown	unknown	gnl|CDD|234710
NZ_CP041168.1|WP_030318864.1|2463802_2464699_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141204474.1|2483029_2484004_-|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl|CDD|237284
NZ_CP041168.1|WP_141204463.1|2465672_2466590_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141204464.1|2466601_2467519_+|chitosanase	gnl|CDD|376538	pfam01374, Glyco_hydro_46, Glycosyl hydrolase family 46. This family are chitosanase enzymes.	8.60247e-126
NZ_CP041168.1|WP_141204469.1|2477467_2478634_+|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	1.70367e-35
NZ_CP041168.1|WP_141204472.1|2480930_2482121_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.42358e-141
NZ_CP041168.1|WP_141204465.1|2467669_2469130_-|glutamate-synthase-small-subunit	gnl|CDD|237213	PRK12810, gltD, glutamate synthase subunit beta; Reviewed.	0
NZ_CP041168.1|WP_141204473.1|2482117_2482945_+|CoA-ester-lyase	gnl|CDD|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	1.02621e-60
NZ_CP041168.1|WP_141204468.1|2476094_2477459_+|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	3.5844e-21
NZ_CP041168.1|WP_141204476.1|2484962_2485781_-|tryptophan-synthase-subunit-alpha	gnl|CDD|237285	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional.	4.45521e-115
NZ_CP041168.1|WP_141204466.1|2469122_2473715_-|glutamate-synthase-large-subunit	gnl|CDD|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NZ_CP041168.1|WP_141204462.1|2464852_2465575_-|VWA-domain-containing-protein	gnl|CDD|378410	pfam10138, vWA-TerF-like, vWA found in TerF C-terminus. vWA domain fused to TerD domain typified by the TerF protein. Some times found as solos.	1.40736e-89
NZ_CP041168.1|WP_141204467.1|2475081_2476098_+|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	3.7557e-47
NZ_CP041168.1|WP_062024641.1|2474093_2474825_-|hypothetical-protein	gnl|CDD|153124	cd02433, Nodulin-21_like_2, Nodulin-21 and CCC1-related protein family. Nodulin-21_like_2: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter. .	1.65043e-96
NZ_CP041168.1|WP_141204477.1|2485777_2487064_-|tryptophan-synthase-subunit-beta	gnl|CDD|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
NZ_CP041168.1|WP_141204479.1|2488308_2488749_-|DUF2752-domain-containing-protein	gnl|CDD|378499	pfam10825, DUF2752, Protein of unknown function (DUF2752). This family is conserved in bacteria. Many members are annotated as being putative membrane proteins.	1.06815e-15
NZ_CP041168.1|WP_141204478.1|2487361_2488171_-|indole-3-glycerol-phosphate-synthase-TrpC	gnl|CDD|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	9.62506e-128
NZ_CP041168.1|WP_141204475.1|2484086_2484860_-|thioredoxin-domain-containing-protein	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	2.67106e-24
NZ_CP041168.1|WP_141204474.1|2483029_2484004_-|prolipoprotein-diacylglyceryl-transferase	gnl|CDD|237284	PRK13108, PRK13108, prolipoprotein diacylglyceryl transferase; Reviewed.	3.45622e-116
NZ_CP041168.1|WP_141204463.1|2465672_2466590_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	1.64168e-31

Protein sequences

>NZ_CP041168.1|WP_141204469.1|2477467_2478634_+|ADP-ribosylglycohydrolase-family-protein
MTPKNQESSLEERIAGALVGAAVGDALGGPVEGYSPDQILERHAGRVHGIVGPWNGDEWRTARPIAPYHKGDGHVTDDTLMTHALIRVYDRVGDHLDAYAIAEHLVPDLMTTPRWIPELEAEALPLHRLFLAEKWLVTRLHYGHVDPREAGVGNIVNCGAAMYMAPVGLVNAANPAAAYAEALDVAGAHQSSYGREAAGVFAAAVAAASAPGATPDSVVAACLSLAKDGTRTAVEKVCEVASRYTDFESALRPLRAAVSPYDTVGDDYRAPSLGARRPSRLHAIEELPVALAMLVVAGGDFRHAVLGAVNYGRDCDSIATMAGAVAGALGSPVPEEWSKKVAEASRLDLWEPARTLTAVTRQIFEQDVRRRRAHESAFTALGGPGCSD
>NZ_CP041168.1|WP_141204468.1|2476094_2477459_+|ADP-ribosylglycohydrolase-family-protein
MTPPAPWDEPTTPTPTPTTATATATATATAYAPAAPPANAPAEAPRDAPSAADGEHPPPGPPAPDHESETGGAGGNAKAEGEAEAGRTVGLLLGLAAGDAAGWPSARHRATRLPDWTRRLTRELDTFAEQNATTTLPVPIALNQSPEPLRLGPSDDAEWAALTAEALLRAADDTALGDLPRDRRTRTAIDLTWNALADEVAAATDRAPEIESADIPLRARISVRAGLGNLATGLRPPATGHDNPHYFDDAACVRACVLAVAHPGAPRLAADLAEFDARYTQDGDGVHGARAMAAALSLALTGAPVDTCVQAALAELPDGTEIARNAHHALDLARSADSAFALIPALEHDIVDHVYSYGIAAAETVPVALALATAARGRIAEAVPAAACLSRVADSAPALVGALTGALGGSGSIPATWQAACRTLSGCALPRLTGTDLVELAGLLEAAQPPLPGG
>NZ_CP041168.1|WP_141204467.1|2475081_2476098_+|ADP-ribosylglycohydrolase-family-protein
MTSIACVPSAPVPQHTAELRDRARGALLGLAVGDALGAPAENLKPSEIRARWGRIEGFVAETPSGTDDTEYTIFSGLLLARHGSALTPAHVEAAWHEWIADRDEGPFRGAGFSERGTLENLRRGLAAPISAQHRHAWSDGLAMRAAPFGVFAAGRPAEAARLVAIDGSVSHDGEGIYGGQAVAAGVAAAMAGAPTIAVVASALAVIPDDSWTARSLRRAVAVAHRGEKAVRSAVVIGGYPWTDLAPEAVALAFGAYAAADGDFREAVLTAVNMGRDADTTAAVAGALAGATRGISAIPPLWATAIGPARGSCLPSMAGRHVLDVAESLVTGAGAEVTP
>NZ_CP041168.1|WP_062024641.1|2474093_2474825_-|hypothetical-protein
MAIIDIEAPLHEAHRDNHTHRDVNGGWLRPAVFGAMDGLVSNLALMTGVAGGAVGQHTIVLTGLAGLAAGAFSMAAGEYTSVASQRELVEAELDVERRELRKHPQDEEAELAALYEGRGVEPELAREVARQLSKDPEQALEIHAREELGIDPGDLPSPIVAAVSSFGSFALGALLPVLPYLLGATALWPAVLLALFGLFACGAVVARVTARSWWYSGLRQLALGGAAAGVTYALGILIGTAVG
>NZ_CP041168.1|WP_141204466.1|2469122_2473715_-|glutamate-synthase-large-subunit
MRTPRQPSQHSTNGQKWSFMDARPAAQGMYDPRNEKDACGVGFVATLTGEASHALVEQALTVLRNLEHRGATGSEPDSGDGAGILSQVPDAFFREVSGFELPAAGTYAVGIAFLPEEGTQEAVSKIETIAGEEGLTVLGWREVPVAPELLGATARSTMPVFRQVFVTDGASEGIDLDRKAFVLRKRAEREVDVYFPSLSARTIVYKGMLTTGQLEPFFPDLSDRRFASAIALVHSRFSTNTFPSWPLAHPYRFVAHNGEINTVKGNRNWMAARESQLVSDLFGDKGLERVFPICTPDASDSASFDEVLELLHLGGRSLPHSVLMMIPEAWENHDSMEPARRAFYEFHSTMMEPWDGPACVTFTDGKQVGAVLDRNGLRPGRYWVTDDGLVVLGSEVGVLDIDPAKVVRKGRLQPGRMFLVDTVEHRIIEDDEIKAGLAAEQPYAEWLEAGEIELSDLPEREHIVHTHASVTRRQQTFGYTEEELRVILAPMAKAGAEPIGSMGTDSPIAALSSRPRLLFDYFTQLFAQVTNPPLDAIREELVTSLRSSLGPQGNLLEPSAASCRTVTLPFPVIDNDELAKLIHINADGDMPGFKAATLSGLYRVSGGGDALAARIEEICAEADAAIENGARLIVLSDRHSDAEHAPIPSLLLTAAVHHHLIRTKQRTQVGLLVEAGDVREVHHVALLIGFGAAAVNPYLAMESVEDLVRAGTFLSGIEPEKAIRNLIYALGKGVLKVMSKMGISTVASYRGAQVFEAVGLEEGFVQKYFSGTASKIGGVGIDVIAKEVAARHAKAYPASGIAPAHRALEIGGEYQWRREGEPHLFDPETVFRLQHSTRANRYDIFKKYTDRVNEQSERLMTLRGLFGFKSDRPSIPVEEVEPVSEIVKRFSTGAMSYGSISKEAHETLAIAMNQLGGKSNTGEGGEDPDRLYDPARRSAIKQVASGRFGVTSEYLVNADDIQIKMAQGAKPGEGGQLPGHKVYPWVAKTRHSTPGVGLISPPPHHDIYSIEDLAQLIHDLKNANPQARIHVKLVSEVGVGTVAAGVSKAHADVVLISGHDGGTGASPLTSLKHAGGPWELGLAETQQTLLLNGLRDRIVVQTDGQLKTGRDVVIAALLGAEEFGFATAPLVVSGCVMMRVCHLDTCPVGIATQNPVLRDRFSGKAEYVVNFFKFIAEEVREILAELGFRSIEEAVGHAETLDVTRAVDHWKAQGLDLAPLFYVPELPEGSALHQVIAQDHGLEKALDNELIKLAADALAADSATDAQPVRAQVKVRNINRTVGTMLGHEVTKKFGGAGLPDDTIDITFTGSAGQSFGAFLPRGVTLRLEGDANDYVGKGLSGGRVIVRPDRGADHLAEYSTIAGNTIAYGATGGELFLRGRTGERFCVRNSGALVVSEGVGDHGCEYMTGGHAVVLGPTGRNFAAGMSGGIAYVVDLDRDNVNVGNVDAVEALDDTDKQWLHDVVRRHQEETGSTVAEKLLAEWDTAVERFSKIIPSTYKAVLAAKDAAEQAGLSESEITEKMMEAAING
>NZ_CP041168.1|WP_141204465.1|2467669_2469130_-|glutamate-synthase-small-subunit
MADPKGFLNHGREVAKSRPVDVRLKDWNEVYVPGSLLPIISKQASRCMDCGIPFCHNGCPLGNLIPEWNDYAYREDWTEASERLHATNNFPEFTGRLCPAPCEAACVLGINQPPVTIKNVEVSIIDKAWDSGDVRPQAPERLSGKTVAVIGSGPAGLAAAQQLTRAGHTVAVYERADRVGGLLRYGIPEFKMEKRHINRRIEQMRAEGTRFRTGIEIGRDLKATDLRKRYDAVVIAAGATTARDLPVPGRELKGIHQAMEYLPLANKVQEGDYVTSPISAEGKHVVVIGGGDTGADCVGTAHRQGAASVTQLEIMPRPGEERNPNQPWPTFPMLYKVTSAHEEGGERVYSVSTTHFEGDEDGNVQWLHLTEVEFIDGKLTPKPGTERKIPAQLVTLAMGFTGTDRENGLVEQFGLELDERGNIARDADFATNVPGVFVAGDAGRGQSLIVWAIAEGRSAARGCDRFLTGASELPAPIRPTDRSLMV
>NZ_CP041168.1|WP_141204464.1|2466601_2467519_+|chitosanase
MLLFAAVPVLATASVYVLAPGDTDASGAGPDLSAAYRAQAAEETEDAEGAKDWAEQAGSSASYKVLGSLPPGLAAPGRKDLAQQLVASAENSTLDWRSAYAYIEDIGDGQGYTAGVIGFCTGTHDLLTLVEGYTKAHPDNGLARYLPALRAVDGTDSHEGLDPGFPAAWRAEAEVPAFRAAQDTARDRVYFDPAVRLAKLDGLGALGQFVYYDAMVFHGPGTDPTSFYGLRERALEKAASPTGGGSERTYLNAFLDLREAAMRTRHPGIDTTRVDTAQRRFLNDGNLELRTPLEWQVYGETFKVP
>NZ_CP041168.1|WP_141204463.1|2465672_2466590_+|rhomboid-family-intramembrane-serine-protease
MEPESTLTTCYRHSKVESHVRCTRCDRFICPDCMQEAAVGHQCPECVREGARSVRQARTAFGGRITAVPLVTYVLIGLNVLAYVGELVRPAIVDRFEMLGAGLAGPDGGHYLWQASYPAELHVEGVVDGEWYRLLTGAFLHLPPTGGTFGILHIVMNMVSLWNIGRVVEAQLGRVRYLALYLLSALGGSVLVLLIAPYDATLGASGAIFGLGAAYWVMARRLGADMSQVNRFMAGLLLWLVISAAMTSWEGHLGGLLTGGAVTLAYAYAPRDGRRALVQAGACAVLLVLLVVCAWAKVAELTGTR
>NZ_CP041168.1|WP_141204462.1|2464852_2465575_-|VWA-domain-containing-protein
MVAISLSKVEETAPALVDLYKSAGVSLVKHGLDGLRAAVYLVVDHSGSMRPYYRDGSVQALADRVLGLSTHLDDDGRVPVVFFSTDIDAETDIELADHQGSVDRIVAGLGHMGRTSYHLAMDAVIDHYLDSGSTAPALVVFQTDGGPINKLAAERYLCKAAKLPLFWQFVAFGNPDSKQFDFLRRLDELPVPDRRAVDNAGFFHAGEDPRTVPDGELYDRLVGEFPKWLEAARAAGIVRA
>NZ_CP041168.1|WP_030318864.1|2463802_2464699_+|hypothetical-protein
MANDGPVQHGYPHLETVRAAITALYKRLSYDTVQTFATSVAPVDVAFCDTDDLYLGAQRVARELVRHYRLPDARFVVSFREMTHAANVELTAGPEYFVELNDRFRTHRRDIGAALAHEVMHVYLHRLDLSFPGVRENEILTDTATTYLGAGWLLLDAYREDAASSQKLGYLTPEEFGYVLAKRSLVFGEDPSVWFTSPQAYTAYGKGLALAREDEQQPPLTAAGWAGRRRYARDRRHGGPGPGQGQGPGTRYAFTPDGTGSLRVSFPCPTCHQRIRVPVRGRVRARCALCRTVLECDT
>NZ_CP041168.1|WP_141204472.1|2480930_2482121_+|CoA-transferase
MTETPLTGLRVLDAATLFAGPLAATMLGDFGAEVVKIEHPTKPDPSRGHGPSKDGIGLWWKLLGRNKRTLTLDLSRPGGRTTFLRLAATADVVIENFRPGTLEKWDLGWPELSAVNPRLVLARVTAFGQFGPYSRRPGFGTLAEAMSGFAAITGEPDAPPVLPPFGLADSIAGLATAYAVMTALAARDRTGAGQVVDMAIIEPILAALGPQPTWYDQLGHVQERTGNRSANNAPRNTYRTADGTWVAVSTSAQSIAERVMHLVGRPELIDEPWFATGAQRAEHADVLDAAVGSWIAARSRTEVLAAFEKAEAAIAPVQDIRDVMADPQYQALDTVTTVDDPELGPLRMQNVLFRLSSTPGAIRWAGRPHGADTDEILTELGLTEAELTALRTEGAL
>NZ_CP041168.1|WP_141204473.1|2482117_2482945_+|CoA-ester-lyase
MRRHPLTWLYVPGDRPHVVDKALNCGADVVVIDLEDAVDPDRKAYAREATAERLTDLQPTPVHVRVNAVDTPLAAADLAALAHLPGLSALRLPKVTSPAQITRVAGTAPADKGAPPLYALLESALGVERAYDIALAHPALRGLALGEADLRADLGVRHDAGLDWSRSRVIVAARAAALPPPSQSVHPDIRDLEGLKASCAHGRALGFLGRAAIHPRQLPVIERAYLPTQEEIEQAESILEAAQAHPGAQALANGTFIDTAVAAQAHRTLSLTRRP
>NZ_CP041168.1|WP_141204474.1|2483029_2484004_-|prolipoprotein-diacylglyceryl-transferase
MELAYIPSPSRGVIHLGPIPLRGYAFCIIIGVFVAVWLGNKRWIARGGRAGTVADIAVWAVPFGLVGGRLYHVITDYELYFSEGRDWVDSFKVWEGGLGIWGAIALGAVGAWIGCRRRGIPLPAYADAIAPGIALAQAIGRWGNWFNQELYGKPTDLPWALHITSSTDGRVPGYYHPTFLYESLWCIGVALLVIWADRRFTLGHGRAFALYVAAYCTGRGWIEYMRIDDAHHILGLRLNVWTAIIVFLLAVTYIVLSARKRPGREEVVEPGAADGPADEGEKADAEETAAGAEKAEGAEKAEADSEDADAEDETKDEAESAKKT
>NZ_CP041168.1|WP_141204475.1|2484086_2484860_-|thioredoxin-domain-containing-protein
MSEKNREGKRTARERLAEERAKQKSAEKRRRVLIVGASVVCVLGLAAVIGVVAANSGKDDKQASGPVVAPSGANGQDSLAIPVGEEGAKSTLVVWEDFRCPACKAFEAAYRPTIHELTGSGKLKVEYHLATIIDGNMGGTGSRTAANAAACAQDMGKFPGYHDVLYENQPEETSDDYAENAKLLELAKKVDGLDTPAFRTCVEKGTHDSWVEKSAAAFRNGGFSGTPTVLLNGKNIYQDQTMTPAKLKQQVLEAAKG
>NZ_CP041168.1|WP_141204476.1|2484962_2485781_-|tryptophan-synthase-subunit-alpha
MSGNIQLLSDTLAAAKAEGRSALIAYLPAGFPTVDGGIEAIKAVFDGGADIVEVGLPHSDPVLDGPVIQTADDIALRGGVKIADVMRTVKEAHEATGKPVLVMTYWNPIDRYGVERFTAELAEAGGAGCILPDLPVQESALWREHAEKHGLATVFVVAPSSRDARLAEITAAGSGFVYAASLMGVTGTRESVGAQAQDLVERTRAARGDLPVCVGLGVSNAQQAAEVAGFADGVIVGSAFVKRMLDAPDDKAGVEGVRELAAELAKGVRRQA
>NZ_CP041168.1|WP_141204477.1|2485777_2487064_-|tryptophan-synthase-subunit-beta
MPSEFFIPDPEGQVPSPEGYFGAFGGKFIPEALVAAVDEVAVEYDKAKHDPEFARELDDLLVNYTGRPSSLTEVPRFAEHAGGARIFLKREDLNHTGSHKINNVLGQALLTKRMGKTRVIAETGAGQHGVATATACALFGLECTIYMGEIDTQRQALNVARMRMLGAEVIAVKSGSRTLKDAINEAFRDWVANVDRTHYLFGTVAGPHPFPAMVRDFHRVIGVEARRQLLERAGRLPDAAIACVGGGSNAIGLFHAFIPDTAVRLIGCEPAGHGVETGEHAATLTAGEPGILHGSRSYVLQDEEGQITEPYSISAGLDYPGIGPEHSYLKDSGRGEYRAVTDDAAMQALRLLSRTEGIIPAIESAHALAGALEVGRELGTDGLIVVNLSGRGDKDMDTAARYFGLYDTDAAVAADEAGTGAEIEGDAK
>NZ_CP041168.1|WP_078616718.1|2487142_2487340_-|hypothetical-protein
MTLTTTTTDRYARLARGCRPRGCRAPARRVHGRRVRYVIGDEPGQVNGMRWQRPVRGAGNCATSH
>NZ_CP041168.1|WP_141204478.1|2487361_2488171_-|indole-3-glycerol-phosphate-synthase-TrpC
MSVLDEIIDGVRADLAERQARVSLDELKERAAKAPAAKDGVAALRGDGVKVICEVKRSSPSKGALAAIADPAGLAADYEAGGAAVISVLTEQRRFGGSLADLEAVRARVDIPVLRKDFIVTSYQLWEARAYGADLALLIVAALEQPALESLIERAESIGLTPLVEVHDEDEVERAVEAGAKVIGVNARNLKTLEVDRGTFERVAPEIPANLVRIAESGVRGPHDLIAYANAGADAVLVGESLVTGKDPKTAVADLVAAGEHPALRHGRG
>NZ_CP041168.1|WP_141204479.1|2488308_2488749_-|DUF2752-domain-containing-protein
MPDVNADTQRALPPEGVLGRLAVPAGILAAVAGAFAYVGTVDPNQPGHYPVCPLYRFTGLYCPGCGGLRSAHAFVHGDVLAALQDNAMAVVGYLAFAVLWTVWVVRAARGRPLRLALGPVQLWTVGALALVFTVVRNLPFGGWLHP
>NZ_CP041168.1|WP_141204480.1|2488827_2489076_-|hypothetical-protein
MAGSSHGHTPAAWTGVTIAFIGFCVAGVFMVMAQPAGFWAGMAIVAIGGIIGWIMSAMGMGMPKDAHKPLVTTKAEAADAKS

Crispr_ID: NZ_CP041168_4

• CRISPR_ID: NZ_CP041168_4
• CRISPR_location: 4178049-4178245
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_4

Consensus_repeat	Method
GGCAGGCACCACCGGACACGGCCGCCCCGAGGACGCCGGACGCCGTG	CRISPRCasFinder

spacers of NZ_CP041168_4

>4.1|4178096|103|NZ_CP041168|CRISPRCasFinder
TCGCGGGACCCTGGGGACAACCGGCACGGGCAGGCACCACCGGACACGGCCGCCCCGAGGACGCCGGACGCCGTGCCCCAGGGCTCCGGGGCCGGGCGGCACA

CRISPR arrays and Neighbor proteins around NZ_CP041168_4

CRISPR arrays

The CRISPR arrays of NZ_CP041168_4

>merge|NZ_CP041168|4|4178049-4178245|CRISPRCasFinder
GCCGGGCACTGCTGGGCGCGACCGCACCGAGGACGCGGGACGCCGTGTCGCGGGACCCTGGGGACAACCGGCACGGGCAGGCACCACCGGACACGGCCGCCCCGAGGACGCCGGACGCCGTGCCCCAGGGCTCCGGGGCCGGGCGGCACAGGCAGGCACCGCCGGACACGGCCGCCCCGAGGACGCCGGACGCCGTG

>NZ_CP041168|4|4|4178049-4178245|CRISPRCasFinder
GCCGGGCACTGCTGGGCGCGACCGCACCGAGGACGCGGGACGCCGTG	TCGCGGGACCCTGGGGACAACCGGCACGGGCAGGCACCACCGGACACGGCCGCCCCGAGGACGCCGGACGCCGTGCCCCAGGGCTCCGGGGCCGGGCGGCACA
GGCAGGCACCGCCGGACACGGCCGCCCCGAGGACGCCGGACGCCGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141209297.1|4169753_4171097_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP041168.1|WP_141205607.1|4171159_4171663_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205606.1|4168411_4169338_-|DUF3027-domain-containing-protein	unknown	unknown	gnl|CDD|378605
NZ_CP041168.1|WP_141205611.1|4174447_4175098_-|HAD-hydrolase-like-protein	unknown	unknown	gnl|CDD|223620
NZ_CP041168.1|WP_141205616.1|4184179_4184872_-|copper-homeostasis-protein-CutC	unknown	unknown	gnl|CDD|225684
NZ_CP041168.1|WP_141205618.1|4187135_4187396_-|DUF4031-domain-containing-protein	unknown	unknown	gnl|CDD|379076
NZ_CP041168.1|WP_020140317.1|4173673_4174057_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP041168.1|WP_141205612.1|4175409_4176447_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
NZ_CP041168.1|WP_141205608.1|4171682_4172345_+|futalosine-hydrolase	unknown	unknown	gnl|CDD|236194
NZ_CP041168.1|WP_141209299.1|4187843_4188719_+|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|224651
NZ_CP041168.1|WP_141205619.1|4187392_4187776_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_078616859.1|4174220_4174481_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141209298.1|4185830_4186910_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP041168.1|WP_141205617.1|4185126_4185768_+|hypothetical-protein	unknown	unknown	gnl|CDD|226789
NZ_CP041168.1|WP_141205610.1|4173232_4173673_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205614.1|4179320_4179854_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_062033590.1|4181661_4181877_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_062033587.1|4180010_4181654_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223989
NZ_CP041168.1|WP_141205615.1|4182108_4184175_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226482
NZ_CP041168.1|WP_141205609.1|4172337_4173228_+|1,4-dihydroxy-6-naphthoate-synthase	unknown	unknown	gnl|CDD|270353

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141209297.1|4169753_4171097_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.52725e-23
NZ_CP041168.1|WP_141205606.1|4168411_4169338_-|DUF3027-domain-containing-protein	gnl|CDD|378605	pfam11228, DUF3027, Protein of unknown function (DUF3027). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.72865e-104
NZ_CP041168.1|WP_141205611.1|4174447_4175098_-|HAD-hydrolase-like-protein	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	5.16135e-21
NZ_CP041168.1|WP_141205616.1|4184179_4184872_-|copper-homeostasis-protein-CutC	gnl|CDD|225684	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism].	3.78608e-26
NZ_CP041168.1|WP_141205609.1|4172337_4173228_+|1,4-dihydroxy-6-naphthoate-synthase	gnl|CDD|270353	cd13635, PBP2_Ttha1568_Mqnd, A menaquinone biosynthetic enzyme exhibits the type 2 periplasmic-binding protein fold. This group includes Ttha1568 (MqnD) from Thermus thermophilies HB8, an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. Ttha1568 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.72325e-142
NZ_CP041168.1|WP_141205617.1|4185126_4185768_+|hypothetical-protein	gnl|CDD|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	5.97874e-46
NZ_CP041168.1|WP_141205612.1|4175409_4176447_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000219973
NZ_CP041168.1|WP_141205608.1|4171682_4172345_+|futalosine-hydrolase	gnl|CDD|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	5.34643e-73
NZ_CP041168.1|WP_141209299.1|4187843_4188719_+|SIS-domain-containing-protein	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.35472e-68
NZ_CP041168.1|WP_141209298.1|4185830_4186910_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.61829e-22
NZ_CP041168.1|WP_141205618.1|4187135_4187396_-|DUF4031-domain-containing-protein	gnl|CDD|379076	pfam13223, DUF4031, Protein of unknown function (DUF4031). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 91 and 130 amino acids in length. There is a conserved HYD sequence motif.	7.17506e-34
NZ_CP041168.1|WP_141205615.1|4182108_4184175_+|AAA-family-ATPase	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	1.08422e-66
NZ_CP041168.1|WP_020140317.1|4173673_4174057_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	4.56793e-27
NZ_CP041168.1|WP_062033587.1|4180010_4181654_+|DEAD/DEAH-box-helicase	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	8.1214e-109

Protein sequences

>NZ_CP041168.1|WP_141205612.1|4175409_4176447_-|hypothetical-protein
MGIESDQVVYEYLSRVGDVAQQRQLPSSTRMRLVSELRNEIDRRRAKAPVDSPAAVRRIIARLGSPDEVVTAAGGSAAVAPQAPAVSMPVQRDRESQDDDGGQRRTGLRKNVPRPRPADPPPPDPAVSHGPHLAGLDELGDPATQPDWWRVDSSPFGVGDSVPGFVGGVEIPELLKPPPPKEEKKPEPAVEQPAAEVPAPGKRTAWWRPRPKAAPPVVEAALAPRRRFLGAGGGSWSNPLLLLAAALLVAGAVLGNLLVLIVGWLIAWASRRLTDAETKWAVVILPGLSLTAGLVWLWGRNEGRWGEPIAQGHMNDAVAETWPWVVRGAAVASALFLVWRSQRRR
>NZ_CP041168.1|WP_141205611.1|4174447_4175098_-|HAD-hydrolase-like-protein
MASASISAPGPTVGFDLDMTLIDSRPGIHACWVELSERTGTYVDADLVVTRLGPPLAEEMAHWFPADRIPQMADLYRELYPAYAIAGTLAMPGAREAIDAVQAAGGRAIVVTAKWEPNARLHMEHLGLEPDAVIGNLWAEQKGEALREHGASVYVGDHTGDVRGARIARATSVAVATGPCSPEELTEAGAEVVLGDLTEFPGWFSDYRADCLPARA
>NZ_CP041168.1|WP_078616859.1|4174220_4174481_+|hypothetical-protein
MRDKTQTNSAAPGDRLIRTGAVVFFVGAVATLVTVAPFLLGTKPFPTYMFGLSMLMAVGFVVAGAGVLQSVAAGRRQARAGRQSAR
>NZ_CP041168.1|WP_020140317.1|4173673_4174057_-|cold-shock-protein
MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVETLKPGQRVEFGVVAGQRGDQALSVAILDPTPSVAAATRKKPDELASIVQDLTTLLENITPMLERGRYPDKAAGKKIAGLLRAVADQLDV
>NZ_CP041168.1|WP_141205610.1|4173232_4173673_-|hypothetical-protein
MHEIRTEPSEELWEYIRRQRRHTLELLIVCAVGLVPWTILLYFTLPSGYTVRQWRVTWVGFDVLLLLAMSATAFLGWRRHRGVVVAAVATGALLVCDAWFDVSLALGTPAVWWSAALAVFVELPLAAFLLRKVLGMMSLAQWPGPR
>NZ_CP041168.1|WP_141205609.1|4172337_4173228_+|1,4-dihydroxy-6-naphthoate-synthase
MTEPSQPSQPSRSVQPSPPLQIAYSPCPNDTFVFDALAHGRVPGAPALDVTFADIDITNGMAERGEFDVLKVSYAVLPYVLDGYTLLPCGGALGRGCGPLVLTREAGLELTGRRVAVPSERSTAYLLFRLWAADVLDGKVGEIVVMPFHEIMPAVRDGLVDAGLVIHEARFTYQNYGLHKLADMGEHWESTTGLPIPLGAIIAKRSLGTERLSRLAESIRASVRAAWDAPEVSRPYVMAHAQEMDPAVADQHIGLYVNEFTADLGEDGYAAIRGLLTRAAAEGLVPALKPDALSFG
>NZ_CP041168.1|WP_141205608.1|4171682_4172345_+|futalosine-hydrolase
MRILVATAVPVERDAVAPAFQGTAAAVDVLAVGVGPALAAAGTATALTRAALEGAAYGLVVSAGIAGGFLPGAPVGSLVVADEITAADLGAETADGFVPVTALGFGAVTHRPPAALVRDAVTATGGRAGAVLTVSTVTGTAERAAALRARHPTALAEAMEGFGVAEAAGAHGVPVLEIRAVSNPVGPRDRAAWRIGDALTALTEGFGKLAPVLESWKQHD
>NZ_CP041168.1|WP_141205607.1|4171159_4171663_+|hypothetical-protein
MTTLQSAVRRRRAVAAAGLVSAGLLVLSACDKPTPRVTVTVGSTSVSSEATCYDDGKDLGQAKATKCALEKSDAKTIKVNQSETLRVGVDPKVADTGWALWINGQQMTYVYKKTYYAFDGVDLFAQQQGQAPQKTLYISIVEQDKTASGQSKEHKGVWNFKLENADY
>NZ_CP041168.1|WP_141209297.1|4169753_4171097_+|MFS-transporter
MTGSVRAVGRALHFPFTGTARGIRKATHAHGAGESGLGKLIELHAVNGAGDVMITVALASTVFFSVPTDEARGRVALYLAITMAPFTVLAPVIGPLLDRLPHGRRAAMAGAMLARALLALIISGAVATGSLELYPAALGVLVASKAYGVVRSAVVPRLLPPRFSLVKANSRVTLGGLLATGIAAPVGAGLQAIGPRWPLYGAFVIFVAGTFLSFSLPPKVDSAKGEDVALLAADEGHLHGPHLKPVKRPGLRTVGTAVTHALGANAALRWLSGFLTFFLAFLLREHPLTGESAAVSLGLVAVSAGAGNALGTAVGAWLKSKAPEIIIVTVVAVVLGAAITAAIFFGAFLVACLAAVAGFAQALSKLSLDALIQRDVPELVRTSAFARSETLLQVSWVFGGAVGIVMPLNGYLGLSVAAAVVAAGWLATAKGLIASARHGSAPRARVA
>NZ_CP041168.1|WP_141205606.1|4168411_4169338_-|DUF3027-domain-containing-protein
MSAATTRSRTPDRLCAEAVDLARAAAEEAAAPGVVGEHAGLVSEGDRVVTHFFESKELGYRGWRWAVTVARASRAKIVTLDEVVLLPGPDALLAPEWVPWSERLRPGDMGPGDLLPTDAEDLRLEPGYTGEDEPLPNAPVSEEMAELVEAEDADVTGGSPAHLPMTPSRGSIAAVAEELGMRRARVLSRYGLHVAADRWEDSFGAQTPMAQAAPAPCVSCGFLVPLGGSLGQAFGLCANEFAPADGRVVSLSYGCGGHSEAAVMPKPPQPAAPVIDETRVDPFPLRPARDSGSVPDTADEASAELGHS
>NZ_CP041168.1|WP_141205614.1|4179320_4179854_-|hypothetical-protein
MSAGRWAAGGGAVVVLVATGAWARWPGGTGVDADLWSRVRPVVEARLLEQVRGSGAGEPGARWFCRAQAVDLEQQGGLVRAGVSTLCLEYGVRARSLVECSGAEVPQVMRLRREADGEYVVVSVETAPDGAGHAEWVTARFGHVTAAALDSAVPSTALEAAARRHFGLPADAPVGPC
>NZ_CP041168.1|WP_062033587.1|4180010_4181654_+|DEAD/DEAH-box-helicase
MNGPLIVQSDKTLLLEVDHEQADACRRAIAPFAELERAPEHIHTYRVTPLGLWNARAAGHDAEQVVDALVQYSRYPVPHALLVDVAETMDRYGRLTLSKHPAHGLVLTTTDRPVLEEILRSKRITPLVGARLDPDTVVVHPSERGQIKQTLLKLGWPAEDLAGYVDGEAHPIELAEDGWALRPYQKQAVENFWHGGSGVVVLPCGAGKTLVGAGSMAQAKSTTLILVTNTVSARQWKHELVKRTSLTEEEIGEYSGTKKEIRPVTIATYQVLTTRRKGVYPHLELFDSRDWGLIVYDEVHLLPAPVFKFTADLQARRRLGLTATLVREDGRESDVFSLIGPKRFDAPWKEIEAQGYIAPADCVEVRVNLTDSERLAYATAEQEEKYRFCATTATKRKVTEALVKRFAGQQILVIGQYIDQLDELGEHLGAPVIKGETSNAQREKLFDAFREGEISVLVVSKVANFSIDLPEATVAIQVSGTFGSRQEEAQRLGRVLRPKADGHQAHFYSVVARDTIDQDFAAHRQRFLAEQGYAYRIVDADELLAES
>NZ_CP041168.1|WP_062033590.1|4181661_4181877_-|hypothetical-protein
MPPLCLIGHHGYMSAATFTPAPGRPSGATPVSSGHTHRLGDALRAVRVFAGAAFDVVILGEYGQEAGVRRK
>NZ_CP041168.1|WP_141205615.1|4182108_4184175_+|AAA-family-ATPase
MSTPLPTDDPLFRERSHLAESRAALRAMREDVESLDIKDVTANWVNAEVLARQIDERIKALADLSDTPLFFGRLDYLHAPGAEQAEGAEGERFYIGRRHVHDHDGDPMVIDWRAPVSQPFYRASKKDPMDVGLRRRFGYTRGDITAYEDEHLSDPAETARTSKLLQQEIERPRVGPMRDIVATIQPEQDEIVRSGLGGTVCVQGGPGTGKTAVGLHRVAYLLYAHRERLARTGTLVIGPNRSFLHYIEQVLPALGELSVQQATVDDLVAKGVEVRGADEAPAAVLKGDARMAEVLRRAVYAHVTMPTEPVMVVRGSRRWRVPAYEIEEIVRELLDRGIRYGAAREALPQRIAHAVLVQMERSGEAPDDRVQDAVARNSAVKAAVKAIWPPVDPAKLVLRLLTDADFLAAHAEGILDEDEQKTILWAKPVRSVKSAKWSAADAVLIDETTDIVERTHSLGHVVLDEAQDLSPMQYRAVGRRCSTGSATVLGDLAQGTTPWATRSWDEALAHLGKSDGVIEELTAGFRVPTDVITYASRLLPHIAPGLTPVASVRENPGFFDLRETSGPGDVVAACEELLRNEGSTGLIAADARVPELADALTAAGIPYLAPGEETTAETRLTLVPASLAKGLEYDYVVLDEPQAVVDGEPDERTGLRRLYVALTRAVSGLIVTHSAPLPEQLAGQGAAR
>NZ_CP041168.1|WP_141205616.1|4184179_4184872_-|copper-homeostasis-protein-CutC
MSKRAVLEVIALDVEDALAARAGGADRLELVTDMAADGLTPAVATVAGIREAVDLPVRVMLRLSDGFGAGDVPRVVRSARELRDAGAEEFVLGFLDAHGEVDLRAVERVVEALDGCRWTFHRAIDHTADRDALRKQLADLPGLDTYLTAGSAAGVDTGLGVLLAEAARAGEPGYEQQLLVGGGLRLDHVPQLRAAGIDAFHIGGAARPCGWEAPVSEEAVREWRRAVDGR
>NZ_CP041168.1|WP_141205617.1|4185126_4185768_+|hypothetical-protein
MADLDDLRARFTAALDAARGTDGPDPLPYADNLLARWQEPQRRYHTLAHLTAVLDHIDVLEPHADDPDLVRLAAWFHDAVYLPDRSENEDRSARLAERALPEAGVPDAATAEVARLVRLTTTHAPADDDRNGQVLCDADLAILAAPPAGYAAYTAAVREEYGFVPTDAFREGRSAILRQLLGLPRLFRTPYGAREWEATARYNLTSELEMLSL
>NZ_CP041168.1|WP_141209298.1|4185830_4186910_+|GNAT-family-N-acetyltransferase
MTEAVAGAVAVLRTVADRDWTAVKPAGMDWTVHETAFHVCGCLIAYAGNLAGGAQDDYVPFDITLDEGTDNTGLLHVMKTGGALLAAAVRTAPREARAFHPYPFRSANREGFAAMGIAEVLLHTYDVARGLDLAYEPPAHLPEYVLTRIFPEAQPGPDPWRTLLWATGRGDLPGRARRTEWRWSNNLVLPAERLTLQGVTPAAAADLAAGCDGGFDWVEDGPFEGTREAAGMTLKAYEAGVHRPEFGLFVLVRREDGRAIGGMGFHGAPDEDGRAEVGYDLAPSARGRGYATEALRALSDWALARDDVRSLCATIEPDNAPSQRVIARAGFLRASVEEEQAYGEKDAGLRLYVLPGPNA
>NZ_CP041168.1|WP_141205618.1|4187135_4187396_-|DUF4031-domain-containing-protein
MTVYIDPPTWPGHGRMWSHLISDVSFDELHAFAEGLGVPSRAFERDHYDIPSHRYADVVAAGAVEVSSREVVRLLTGAGLRRPKGR
>NZ_CP041168.1|WP_141205619.1|4187392_4187776_-|hypothetical-protein
MESIGPLEQSLHTARALVLADLAVGDVAAPDVVSMVEDSVVQRRWWVEQWPEGADFVAGLVAQDVQDAILERHGRWPLCPVCGAGDPHALEVEPELGADPHWVCHKAGVKVAAIGSLGTATGEAPSP
>NZ_CP041168.1|WP_141209299.1|4187843_4188719_+|SIS-domain-containing-protein
MKEIFGSALAAKVRTLGPSMTRSMQRVAEAVASDPAGCAALTVTGLAERTGTSEATVVRTARLLGYPGYRDLRLALAGLAAQQQSGRSPAITTDIAVDDPIADVVAKLAYDEQQTLADTAAGLDTVQLGAAVAATASARRIDVYGVGASGLVAQDLTQKLLRIGLIAQAHSDPHLAVTNAVQLRSGDVAIAITHSGSTGDVIEPLRVAFEHGATTVAITGRPGGTVAQYADHVLTTSTARESELRPAAMSSRTSQLLVVDCLFVGVAQRTYDTAAPALAASYEALAHRHRR

Crispr_ID: NZ_CP041168_5

• CRISPR_ID: NZ_CP041168_5
• CRISPR_location: 4220810-4220884
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_5

Consensus_repeat	Method
GCCTCAAGCCTCAAGACCCGGGCTTCGG	CRISPRCasFinder

spacers of NZ_CP041168_5

>5.1|4220838|19|NZ_CP041168|CRISPRCasFinder
ACCTCAGGTCTCAGCTCAG

CRISPR arrays and Neighbor proteins around NZ_CP041168_5

CRISPR arrays

The CRISPR arrays of NZ_CP041168_5

>merge|NZ_CP041168|5|4220810-4220884|CRISPRCasFinder
GCCTCAAGCCTCAAGACCCGGGCTTCGGACCTCAGGTCTCAGCTCAGGCCTCAAGCCTCAGGCCTCAAGACCCGG

>NZ_CP041168|5|5|4220810-4220884|CRISPRCasFinder
GCCTCAAGCCTCAAGACCCGGGCTTCGG	ACCTCAGGTCTCAGCTCAG
GCCTCAAGCCTCAGGCCTCAAGACCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_020140122.1|4231644_4232103_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_020140110.1|4218044_4218215_+|hypothetical-protein	unknown	unknown	gnl|CDD|372724
NZ_CP041168.1|WP_141205646.1|4218287_4219160_-|oxidoreductase	unknown	unknown	gnl|CDD|236676
NZ_CP041168.1|WP_141205651.1|4224912_4226346_+|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_CP041168.1|WP_141205640.1|4214331_4215156_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP041168.1|WP_141205642.1|4215711_4215960_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205649.1|4222954_4223680_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP041168.1|WP_141205645.1|4217436_4217862_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205647.1|4219340_4220204_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182183
NZ_CP041168.1|WP_141205648.1|4222364_4222865_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141209303.1|4226519_4227902_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274522
NZ_CP041168.1|WP_141205644.1|4216912_4217326_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205655.1|4230282_4231419_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl|CDD|236947
NZ_CP041168.1|WP_141205643.1|4215972_4216800_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205652.1|4227928_4228570_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141205654.1|4229490_4229970_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP041168.1|WP_141205650.1|4223842_4224820_+|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176206
NZ_CP041168.1|WP_141205653.1|4228568_4229489_+|hydroxyurea-phosphotransferase	unknown	unknown	gnl|CDD|309685
NZ_CP041168.1|WP_141205641.1|4215309_4215711_+|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP041168.1|WP_141205639.1|4214131_4214335_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141209303.1|4226519_4227902_-|FAD-dependent-oxidoreductase	gnl|CDD|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	3.11435e-56
NZ_CP041168.1|WP_020140110.1|4218044_4218215_+|hypothetical-protein	gnl|CDD|372724	pfam13779, DUF4175, Domain of unknown function (DUF4175).	0.00584676
NZ_CP041168.1|WP_141205646.1|4218287_4219160_-|oxidoreductase	gnl|CDD|236676	PRK10376, PRK10376, putative oxidoreductase; Provisional.	0
NZ_CP041168.1|WP_141205651.1|4224912_4226346_+|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.59165e-66
NZ_CP041168.1|WP_141205640.1|4214331_4215156_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	2.14845e-06
NZ_CP041168.1|WP_141205649.1|4222954_4223680_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.641e-18
NZ_CP041168.1|WP_141205650.1|4223842_4224820_+|zinc-binding-dehydrogenase	gnl|CDD|176206	cd08244, MDR_enoyl_red, Possible enoyl reductase. Member identified as possible enoyl reductase of the MDR family. 2-enoyl thioester reductase (ETR) catalyzes the NADPH-dependent dependent conversion of trans-2-enoyl acyl carrier protein/coenzyme A (ACP/CoA) to acyl-(ACP/CoA) in fatty acid synthesis. 2-enoyl thioester reductase activity has been linked in Candida tropicalis as essential in maintaining mitiochondrial respiratory function. This ETR family is a part of the medium chain dehydrogenase/reductase family, but lack the zinc coordination sites characteristic of the alcohol dehydrogenases in this family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. Candida tropicalis enoyl thioester reductase (Etr1p) catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis. Etr1p forms homodimers, with each subunit containing a nucleotide-binding Rossmann fold domain and a catalytic domain.	1.1335e-117
NZ_CP041168.1|WP_141205647.1|4219340_4220204_+|LysR-family-transcriptional-regulator	gnl|CDD|182183	PRK09986, PRK09986, LysR family transcriptional regulator.	1.23271e-33
NZ_CP041168.1|WP_141205653.1|4228568_4229489_+|hydroxyurea-phosphotransferase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	1.09585e-53
NZ_CP041168.1|WP_141205655.1|4230282_4231419_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	2.96237e-180
NZ_CP041168.1|WP_141205654.1|4229490_4229970_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.57905e-15
NZ_CP041168.1|WP_141205641.1|4215309_4215711_+|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	9.18621e-19
NZ_CP041168.1|WP_141205639.1|4214131_4214335_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.35217e-18

Protein sequences

>NZ_CP041168.1|WP_141205647.1|4219340_4220204_+|LysR-family-transcriptional-regulator
METLETRELRYFLAVAEELHFGRAAQRLGMAQPPLSRAVQQLERRLGVRLLERNRRGVALTGAGEMLLHEGRAALDAVTAAARRTSRAGETDGTGARRNRLVLAVKAAASHELLHKLLDAYAAEPGAVEVEVLPSGTCEQGEMLRDGRADVALMHAPFNSLAGFDSEELLTEGQIAVLPAGHPLAARESLSLADVTDVPDLPLARWSHDGTYPPGPGPEIHDQTQLAQLIALGRTVAVFPDSARAWLWSDHAAVPLTDAPPVVTHIAWPAHSRSLPLATLIRTATRL
>NZ_CP041168.1|WP_141205646.1|4218287_4219160_-|oxidoreductase
MNTPSAALPGGTWSLGDLTVTRFGYGAMQLAGPGVMGPPADHDGAVAVLREAVDLGITHLDTAGAYGPRVTNRLIREALHPFPASLHIVTKVGAERDGQGGWPPARRPEELRRAVHENLEDLGLDALDVVNLRLGDAQGPRPGSLAEPFEALAELRRQGLIRHLGVSNATAEQVAEARGIAPVVCVQNLYNLAHRHDDDLIDDLAAEGIAYVPFFPLGGFTPLQSSALTAVATRLDATPMSVALAWLLQRSPNILLIPGTSSVAHLRENITGAGLTLSDEDVTELDKIGA
>NZ_CP041168.1|WP_020140110.1|4218044_4218215_+|hypothetical-protein
MVPLLVVLLLALLLFGAGFALKALWWLAVIVLVVWLLGFVLRSADAGGRKGRWYRW
>NZ_CP041168.1|WP_141205645.1|4217436_4217862_-|hypothetical-protein
MTKREKSVKKRIGLAVLVAGLLATAALGLRSLLYAEGWVGTIGTYRASSCDYSSGEGAWNCSGTFVSSDGRVDDPRAEVSLSGDAKGRSVRVNSSGDGDYQEIGGFAVAGAVSLILFGAGPLAVVAALELRKRHKSSKLPR
>NZ_CP041168.1|WP_141205644.1|4216912_4217326_-|hypothetical-protein
MPNTPDPGTPEAVDGEEPWLSSDEVAKLWPIRKDWLSGAAHRADVRVRRSGGASRGTWGAEPTFYHFHPEDVRRAAPAIAEGHVDIPSVWRTDTPDGRRREFWGTLSARVAGTLVLALLVFAIILLLGTVVFLLTVE
>NZ_CP041168.1|WP_141205643.1|4215972_4216800_-|hypothetical-protein
MRTRCAVTAVVSGAVVLSALAVPVAAQAAERTSALTKSSPNDSLGNTKFSNAVVNGGKDIVLGTTGTKSVVVTYTATDQNGVALTEAFLWQGTDSSTTEGITGGLGTDDDPDCTETATQGVYKCKAVFTIHPATDMKDNGVAGTWKLFLGAWDLYANASYNDDVTTAAIKKAATLTADATPEPVRKGGTLTVTGKLARANWSTGKYAGYVSQPVKLQFRKKGSNTYTTLKTIKTNSTGVLRTTTKATVDGYYRYSFAGTSTTAPATAPGDFVDVR
>NZ_CP041168.1|WP_141205642.1|4215711_4215960_-|hypothetical-protein
MNDTEHDGPPGEAELRIPLALVALVLYSGALVRFLTGFLSGFSVGKLMEGLVGLAFETGMTTALVLAVVLFRRRRQRGAGQG
>NZ_CP041168.1|WP_141205641.1|4215309_4215711_+|ATP-binding-protein
MNQETTAIRNFSVPLSATPRGARLARLLACEQLREWGLPLDPAEHLVAELAANAATHGRVPGRDFRLTLYVVGDTLRIEVTDTRGDRLPHPELPPPDAESGRGLLLVDALSTRWGVSPGPAPRKTVWAEVTFP
>NZ_CP041168.1|WP_141205640.1|4214331_4215156_-|helix-turn-helix-domain-containing-protein
MSVDGETVDPDDEWGVAVIATVGRQLKLRREAVGMRAGEFGEAVGYGEDLVYKIEGGKRIPRQEYLDRADEVLGAGGLISAAWEDVKKVRYPKKVRELAKLEGRAVEIGVYECNIVAGLLQTPEHARAVISAAQPPYSPDDVERMVNARLARQSVFERDPAPSIHFVLEEAALRRPIGGTMVWRRQLEHLLEVGQLHNVVLQVMPLNTEVHSGLDGRIEVLKFPDGTAVGRSDGRATSDPKQLRILELRYGTIRAQALSPGESLILIEQLLGAT
>NZ_CP041168.1|WP_141205639.1|4214131_4214335_-|DUF397-domain-containing-protein
MIRKSAAGDVSDLAWFKSSYSGGNDGNSCVEIAVAPRSVHVRDSKHDTIGPRLAFTPASWTVFVSQA
>NZ_CP041168.1|WP_141205648.1|4222364_4222865_+|hypothetical-protein
MLDIGYALSNRFPDPPQTDYRRADVHALRHDLFCGDVYLADTKEDRELSTAWGWVPVLDFAWALCDIAERLDRDPAGSRASRPQHAELDFTESTDRMLFERRFGWVDVEADWMRAEEPPLTFSHAELRREARDFLHDLIADLIDLHEDLAENPAIWTLQARFPRVK
>NZ_CP041168.1|WP_141205649.1|4222954_4223680_-|pentapeptide-repeat-containing-protein
MLLQVRSVVSGGVQDGGMVSRGTGAGRVKGARRPEVRLPPLEAFGGGELEPDGDYDGLEFPEKDLAGQDGAGARFMDCALRGCALDETRLHHARFLDSVLTGVRGVGTDLAESTLRDVELVDARLGGVQLHGAALERVVIRGGKIDYLNLRTAVLRDVVFEGCVLVEPDFGGARLERVEFVDCALKGVDLTAATLKDVDLRGAVSLEIARGVDRLAGAVISPSQLLDLAPVLAAEVGIRVE
>NZ_CP041168.1|WP_141205650.1|4223842_4224820_+|zinc-binding-dehydrogenase
MHAIRLHRFGPAENLTYETTDDPAPGPGQVRVAVRAAGVHLLDTALREGHRGPLPEPPALPTVPGREVAGIVESLGDGVAGPWLGKRVVAHLGFAPGGYAELAVTDVDRVHEIPADLDFAQAVAMIGTGRTAMGIVQFAELGPDSVVVIPAAAGGIGTLLVQYAKNAGATVVGLAGGPRKAALVAENGADLAVDYRDSAWAGKVRAFLGGRPATVVFDGVGGAIARASVRLLGPEGQHIVFGWSGEGIHDGHPYLVEGVSEQVLGPAMLRKAGPDPLRTLELRALTEAAAGRLRPAVQRFPLAEAAAAHRALETRGTTGKVVLEP
>NZ_CP041168.1|WP_141205651.1|4224912_4226346_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MVIALAQLMVVLDATIVNIALPSAQQDLGMSDANRQWVITAYTLAFGGLLLLGGRIADLVGRKRTFMIGLVGFAAASALGGAATGSGMLFAARALQGVFAAVLAPSALSLLTTTFTDPKERGKAFGIYGALAGSGSAIGFIVGGLLTEYLNWRWCLYVNVPIAVVAFFGALVLLHDRPGHAGARLDVPGVLLGCGGLVAIVYGFSEAQPRGWSDPLVLTLLGGGVVLLAIFVWWQSRAPMPLLPLHIVKDRNRAGCFLTMGLAVIGMFGLFLFMTYYLQVVLAYSPVRTGLAFLPMTAAIIVGSTQISARLMNRVAPRMLMVPGMVLAASGMVILTQMTVDSSYTTEILPALLLMGLGMGLTFMPVFSTATAGVAPQDSGVTSATVNTSQQVGGSIGTALLNTIATTSSTAYITAHLTDPSRKALIVKEGVVHGYTVAIWWAAGIMLLAGLIAGLMVTAKPPKQGAPAPTPVPESVA
>NZ_CP041168.1|WP_141209303.1|4226519_4227902_-|FAD-dependent-oxidoreductase
MNGGISFWYADDGFPEAREPLAGDASADVVIVGGGYTGLWTAYYLKKAVPFLRITVLEQKFCGYGASGRNGGWLYNGVAGRDRYAKLHGHEAAVRLQRAMNDTVDEVVRVVGEEGFDAGLHKGGVLEVARTPAQLARLRAFHEHELSYGEKDRELYGARETARRVRVAGAVGASWTPHGARVHPVRLVKGLAAAVEALGVVVHEQTPLTEIRPKHAVTPYGTVRAPYVLRCTEGFTAALKGQRRTWLPMNSSMIATEPLSEEQWAAIGWEGRQTLGDMAHAYMYAQRTADGRIALGGRGVPYRYGSRTDNDGRTQAATVEALREILVDFFPMLAGTRIEHAWSGVLGVPRDWCASVTLDRSTGIGWAGGYVGSGVATANLAARTLRDLVRQDSGQGGRTELTDLPWVGHKVRKWEPEPLRWLGVQGMYATYRTADRRETASHSAESSRLARWADRVAGRH
>NZ_CP041168.1|WP_141205652.1|4227928_4228570_-|hypothetical-protein
MRINRGVHRVGEYVRRAPGTYVWLTVLFVTTVALHHMSPTFEEQFLRQRSTNIHELSSNPVRVLVASAMWIDSGHWLPYVVLFSVFHAQAERWLGTARWLAVCAAAHVLATLISEGALLWGIRHGMAPESAVNTLDVGVSYALAGVVAVLVYRIPRPWRYVYGFVVLVVYAVPLVTGRTFTDLGHFTSALIGFGCYPLVGVRNPKETAGASAG
>NZ_CP041168.1|WP_141205653.1|4228568_4229489_+|hydroxyurea-phosphotransferase
MSRFTHAGRVRHVIDIPAALAAAQERYNGDRGREFVAGLPALVEEFLERWALRPDGAPLHGVTALVLPVRQDGTPAVLKLQLLDEESAGEPVALRRWDGDGAVRLLDHDPVTHTMLLERLDSTRMLSTLPGTRDAVLVIARLLAHLTAGPAPAGIRRLGDIAHAMLEQTPRALPRIPDPRIRRTVADCAAAVREVVDEPGDRLLHWDLHDENVLASDRAPWLAIDPKPLAGDPGFDLWPALDNRFDADEITWRFDAMTDVLGLDRARARAWTMGRLLQNALWDIEDGRPLEPRQLEIAHRLRTPGA
>NZ_CP041168.1|WP_141205654.1|4229490_4229970_+|GNAT-family-N-acetyltransferase
MIRPATPADIPAIHALIRELADYEKSLPEARATEDQLHEALFGAHPAVHAHVATDPTGAVIGYAVWFLNFSTWRGVHGIYLEDLYVRPQSRGAGHGKALLTELARICVARGYQRLEWSVLDWNTPAIDFYESLGARPQNGWTVYRLTDDALTKAASGTA
>NZ_CP041168.1|WP_141205655.1|4230282_4231419_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MATVSFDKATRIYPGSTKPAVDGLDIHIEDGEFLVLVGPSGCGKSTSLRMLAGLEDVNGGAIRIGDRDVTHLPPKDRDIAMVFQNYALYPHMTVADNMGFALKIAGVNKAEIRQKVEEAAKILDLTEYLDRKPKALSGGQRQRVAMGRAIVREPQVFLMDEPLSNLDAKLRVSTRTQIASLQRRLGITTVYVTHDQVEAMTMGDRVAVLKDGLLQQVDSPRNMYDRPANLFVAGFIGSPAMNLVEVPITDGGVKFGNSVVPVNREALKAASDKGDTTVTVGVRPEHFDVVEHNGAAASALSKDTEDAPAGLAVSVNVVEELGADGYVYGSAKVGDELKDLVVRVSGRAVPEKGATLHVVPRPGETHVFSTSTGERLSD
>NZ_CP041168.1|WP_020140122.1|4231644_4232103_+|hypothetical-protein
MKHSTYQQTRRGRGPARRIGRSLALVLPVVLVLSGTLAVTRVNWSGDPSSSSVLTASDATVSDGKPRSAPLAPQDVLRERLLTELQEKDPGTALTHLQEAVNGRPSLAKHCVSIARALGRAAVRVYGPTRAQSYARPVCDTSFATGVAAAHS

Crispr_ID: NZ_CP041168_6

• CRISPR_ID: NZ_CP041168_6
• CRISPR_location: 5257800-5257953
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP041168_6

Consensus_repeat	Method
GCACCGGACCGGCGTGCGGCGCCGG	CRISPRCasFinder

spacers of NZ_CP041168_6

>6.1|5257825|50|NZ_CP041168|CRISPRCasFinder
GGACAGGCGGTCCTACGGGTACGGAGCGGGTGAGCCGCGCGAGGCGCCTG
>6.2|5257900|29|NZ_CP041168|CRISPRCasFinder
ACCGGCATGCCCCACCGGACCGGCGTGCC

CRISPR arrays and Neighbor proteins around NZ_CP041168_6

CRISPR arrays

The CRISPR arrays of NZ_CP041168_6

>merge|NZ_CP041168|6|5257800-5257953|CRISPRCasFinder
GTGCCGGACCGGCGTGCCGTCGGCGGGACAGGCGGTCCTACGGGTACGGAGCGGGTGAGCCGCGCGAGGCGCCTGGCACCGGACCGGCGTGCGGCGCCGGACCGGCATGCCCCACCGGACCGGCGTGCCGCACCGGACCGGCGTGCCGCGCCGG

>NZ_CP041168|6|6|5257800-5257953|CRISPRCasFinder
GTGCCGGACCGGCGTGCCGTCGGCG	GGACAGGCGGTCCTACGGGTACGGAGCGGGTGAGCCGCGCGAGGCGCCTG
GCACCGGACCGGCGTGCGGCGCCGG	ACCGGCATGCCCCACCGGACCGGCGTGCC
GCACCGGACCGGCGTGCCGCGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141206322.1|5250831_5251839_-|A/G-specific-adenine-glycosylase	unknown	unknown	gnl|CDD|224115
NZ_CP041168.1|WP_020141090.1|5248617_5249322_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP041168.1|WP_028810200.1|5253140_5254265_-|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl|CDD|237395
NZ_CP041168.1|WP_141206329.1|5263714_5265808_-|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl|CDD|270916
NZ_CP041168.1|WP_141206319.1|5245581_5247156_+|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_CP041168.1|WP_141209380.1|5258090_5258897_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206327.1|5260952_5261591_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380054
NZ_CP041168.1|WP_141206320.1|5247271_5248603_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP041168.1|WP_141206328.1|5261802_5263656_+|dihydroxy-acid-dehydratase	unknown	unknown	gnl|CDD|237104
NZ_CP041168.1|WP_030323816.1|5260131_5260956_+|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NZ_CP041168.1|WP_141206324.1|5254346_5255756_-|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NZ_CP041168.1|WP_141206321.1|5249404_5250082_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206330.1|5265990_5266308_+|SH3-domain-containing-protein	unknown	unknown	gnl|CDD|227324
NZ_CP041168.1|WP_141206332.1|5266716_5267226_+|EamA/RhaT-family-transporter	unknown	unknown	unknown
NZ_CP041168.1|WP_141206331.1|5266326_5266662_+|SH3-domain-containing-protein	unknown	unknown	gnl|CDD|227324
NZ_CP041168.1|WP_020141092.1|5250066_5250609_-|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_CP041168.1|WP_141206325.1|5256038_5257742_+|hypothetical-protein	unknown	unknown	gnl|CDD|274357
NZ_CP041168.1|WP_141206323.1|5252187_5253045_+|hypothetical-protein	unknown	unknown	gnl|CDD|164795
NZ_CP041168.1|WP_141206333.1|5267571_5268351_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|369777
NZ_CP041168.1|WP_141206326.1|5259073_5260015_+|Ppx/GppA-family-phosphatase	unknown	unknown	gnl|CDD|223326

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141206322.1|5250831_5251839_-|A/G-specific-adenine-glycosylase	gnl|CDD|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.69098e-80
NZ_CP041168.1|WP_020141090.1|5248617_5249322_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.91957e-82
NZ_CP041168.1|WP_028810200.1|5253140_5254265_-|DNA-integrity-scanning-protein-DisA	gnl|CDD|237395	PRK13482, PRK13482, DNA integrity scanning protein DisA; Provisional.	0
NZ_CP041168.1|WP_141206329.1|5263714_5265808_-|PQQ-binding-like-beta-propeller-repeat-protein	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.18296e-83
NZ_CP041168.1|WP_141206319.1|5245581_5247156_+|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.73529e-69
NZ_CP041168.1|WP_141206327.1|5260952_5261591_+|TetR-family-transcriptional-regulator	gnl|CDD|380054	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins found in Actinobacteria. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	4.8101e-33
NZ_CP041168.1|WP_141206320.1|5247271_5248603_-|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.23796e-31
NZ_CP041168.1|WP_141206328.1|5261802_5263656_+|dihydroxy-acid-dehydratase	gnl|CDD|237104	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional.	0
NZ_CP041168.1|WP_030323816.1|5260131_5260956_+|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	9.53999e-29
NZ_CP041168.1|WP_141206324.1|5254346_5255756_-|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP041168.1|WP_141206330.1|5265990_5266308_+|SH3-domain-containing-protein	gnl|CDD|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	1.5886e-08
NZ_CP041168.1|WP_141206331.1|5266326_5266662_+|SH3-domain-containing-protein	gnl|CDD|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	4.82467e-11
NZ_CP041168.1|WP_020141092.1|5250066_5250609_-|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	2.71843e-56
NZ_CP041168.1|WP_141206325.1|5256038_5257742_+|hypothetical-protein	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	5.53181e-08
NZ_CP041168.1|WP_141206323.1|5252187_5253045_+|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	3.37469e-05
NZ_CP041168.1|WP_141206333.1|5267571_5268351_+|methyltransferase-domain-containing-protein	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.54788e-19
NZ_CP041168.1|WP_141206326.1|5259073_5260015_+|Ppx/GppA-family-phosphatase	gnl|CDD|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	1.44246e-82

Protein sequences

>NZ_CP041168.1|WP_141206325.1|5256038_5257742_+|hypothetical-protein
MMSSTPETSTRTTGAHRAQREERDRGAARTLAQRPPGRYEPYLDGLFTYCLSVLCEHEAATAALGEVLALAEKRGGPDAAGDRRAWLYALARWACLRKLAEAKQKRQATHAAGRHGASATVAGPPVAEDVLAERRRELAQLAWPEAAGTTPEQREALELAVRHHLAAHEVAAVLGMDLAGARELLASAACEVERTRAALAVVETGDCPGVARLTGDNQFVLSSALRRELVRHVDDCPRCRRGAERAIPGRWPGAMTTPAELPVLEAPRAALHMALAHPPRARGAGVPRFDRRGFPMDPKDRAARRDRLRARAVTTTVVATVVAAPVLALWAAYRGGPGEGADGHSASASEAHGPGTLDGANASGGYQNAGNASVKPGPRFTKDGRPDVSVEVVSVTGVGKKGAGQLEVAAGNDGDTTLVTLTANGAAPVRWSATTGASWLYLSHSSGTLKPGQSLTIKVYVDHLREPSGPWSARVAISPAGAVVTIHGYGTAPTPTGPGPRPTPPSGPPSSSDPDPTPTGPTSPPDGSEPPPSPDPTLTASTDPSSPTPSDSTPPPSEGDDPSPSTS
>NZ_CP041168.1|WP_141206324.1|5254346_5255756_-|DNA-repair-protein-RadA
MATRTKSAKERPSYRCTECGWQTAKWLGRCPECQAWGTIEEYGAPAVRTTTPGRVTTSAVPIGQVDGRQATARSTGVPELDRVLGGGLVPGAVVLLAGEPGVGKSTLLLDVAAKSASDEHRTLYVTGEESASQVRLRADRIGAIDDHLYLAAETDLSAVLGHLDAVKPSLLILDSVQTVASPEIDGAPGGMAQVREVAGALIRASKERGMSTLLVGHVTKDGAIAGPRLLEHLVDVVLSFEGDRHARLRLVRGVKNRYGATDEVGCFELHDEGITGLADPSGLFLTRRDEPVPGTCLTVTLEGRRPLVAEVQALTVDSQIPSPRRTTSGLETSRVSMMLAVLEQRGRISALGKRDIYSATVGGVKLSEPAADLAIALALASAASDTPLPKNLVAIGEVGLAGEVRRVTGVQRRLSEAHRLGFTHALVPGDPGKIPAGMKVMEVADIGDALRVLPRSRRREAPQDAEDRR
>NZ_CP041168.1|WP_028810200.1|5253140_5254265_-|DNA-integrity-scanning-protein-DisA
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGFDKTVETMCTGGFVLDVEFAATRLRELCKLDGGIVLSSDLSKILRAGVQFVPDATIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIAGVEPERELVVRDYVPEPTAKRSRTVDEALYELNVLSHAELLELTTVARALGYTGSPESLDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV
>NZ_CP041168.1|WP_141206323.1|5252187_5253045_+|hypothetical-protein
MGSLRNPVGPLPSSIYWRRRAVMLSVLAVLALLIAWIVSFGGGGGDKNGADGSNGKNPTPSTISPGPSGSGPAISQAPGGRDESTTGGDTSGGAGSGGGAGDGSDVGDAGSGGAGGSDAGGSGGTDGAGAAGGGAAGSGVGQGDTLPAGSSLPNCTPGSLKLSVRSQRNAYEPGQTPTLLLTATNSSGSDCKVDLGPKNAVLTITQADSDDTYWSSADCPKTAGNLVFRAPAGSSITYTVKWDRKPSAPQCATPPAGSAGAGTYLVEVKKPGYPTVQASFVLEND
>NZ_CP041168.1|WP_141206322.1|5250831_5251839_-|A/G-specific-adenine-glycosylase
MTAPTKPSPSRPAADSTGPALADTNGAPPADAAATPLADTAGAPRGEDLHAPVIDWFDEHARDLPWRRPEAGPWGVMVSEFMLQQTPVSRVLPVYEQWLARWPRPADLAQEAPGEAVRAWGRLGYPRRALRLHGAAVAITERHGGDVPTDHAHLLALPGIGEYTAAAVASFAYGQRHAVLDTNVRRVFARAVTGVQYPPNATTAAERKLARALLPRDEATAARWAAASMELGALVCTAKNETCGRCPIAAQCAWRLAGKPAHDGPARRGQTYAGTDRQVRGKLLAVLREAHAPVPQAVLDRVWHEPVQRARALDGLVADGLVEPLAGGLYRLPLT
>NZ_CP041168.1|WP_020141092.1|5250066_5250609_-|SigE-family-RNA-polymerase-sigma-factor
MAQGEVLEFEEYVRTRQDALLRSARRLVPDPVDAQDLLQTALVRTYGRWETIEDKRLADAYLRRVMINTRTEWWRARKLDEVPTEQLPDASVDDSTEQHADRALLMDVMKVLAPKQRSVVVLRHWEQMSTEETAAALGMSVGTVKSTLHRALARLREELEARDLDARALEREERERCAAA
>NZ_CP041168.1|WP_141206321.1|5249404_5250082_-|hypothetical-protein
MRGGLTEPGPTGSDPAPVRGILQAASTAVAVLAALALFVSACATGGTGTRDEGPAHAVAGTGARSAAVPSLASSPRLDRSSAVALLKSDPKVSEAVKRDLKPCVADEYPVDLSYGDLTGGSADDVVVNVVTCADLVGVGSYVYREEDGSYQNVFQAEEPPVYAEIDRGDLVVTKQVYEKGDPVSAPSGENVITYRWAAGKFATVYRTHSDYSGVVGTDPAPTPDN
>NZ_CP041168.1|WP_020141090.1|5248617_5249322_-|response-regulator-transcription-factor
MADQTHVLFVEDDDVIREATQLALERDGFAVTAMPDGLSGLEAFRADRPDIALLDVMVPGLDGVSLCRRIRDESTVPVIMLSARADSIDVVLGLEAGADDYVTKPFDGAVLVARIRAVLRRFGHAGGADRGEESAAPDAGGVLTFGELEIDTEGMEVRKGGQPVGLTPTEMRLLLEFSSAPGTVLSRDKLLERVWDYGWGGDTRVVDVHVQRLRTKIGQDRIETVRGFGYKLKA
>NZ_CP041168.1|WP_141206320.1|5247271_5248603_-|HAMP-domain-containing-protein
MRGIFRSPVTERVVMRTGLRWKLSAAIALVGALVAVALSLVVHNAARVSMLDNARDLADERIRIAQRNYELTGKPNFPSIVVDDRHLPPPLRRKVEEGRRATFVSDRPDRGPDIWAAVPVKGGHVLSLHTGFTDRSTDILKDLDQALVIGSIAVVLGGSALGVLIGGQLSRRLRKAATAANQMAKGETDVRVRDAIGGVVQDETDDLASAVDAMADALQQRLEAERRVTADIAHELRTPVTGLLTAAELLPPGRPTELVLDRAKAMRTLVEDVLEVARLDGASERAELQDILLGEFVARRVAAKDPEIEVRVVHESEVTTDPRRLERVLFNLLANAARHGKPPIQVTVEGRVIRVRDHGPGFPEDLLADGPSRFRTGSADRAGHGHGLGLTIAAGQARVLGARLTFRNVRPAGAPDEIPSEGAVAVLWLPEHAPTATGSHPLP
>NZ_CP041168.1|WP_141206319.1|5245581_5247156_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MADTQTVETEPDKEPAKQRSVRVVLLALMITMMLAMLDNMIVGTAMPTIVGELGGLEHLSWVVTAYTLATAAATPIWGKLGDMYGRKATFMTSIVIFLIGSALSGMAQDMGQLIGFRAVQGLGAGGLMVGVMAIIGDLIPPRERGKYQGMMAGVMALAMIGGPLVGGTITDNWGWRWSFYINLPLGVVALGLISVVLHLPKKRAKAGIDYLGVVLLTVGITSIVLVTTWGGTEYAWTSARIMELIGIGVAALIGFVFWQTKAAEPIVPLHIFRSRNFTLMSLIGFITGFVMFGATLFLPLYQQSVQGASATNSGLLLLPMLGAMLVTSMVAGRVTTSSGRYYVFPVVGSVLMVVGLYLLSTMDTGTSRFTSGVFMAVVGFGMGCLMQITMLVAQNSVEMKDMGVASSSTTLFRTLGSSFGVAIMGALFNNRVQDVMSERAGALGSKVTEQSAQLDAASLAKLPAAAREAYQYAVSAGTHSAFLLGSIVAVLALVAAVFVKEVPLKGAGPQKQTEDAAPAPLVEV
>NZ_CP041168.1|WP_141209380.1|5258090_5258897_-|hypothetical-protein
MSKKARQALAADEKGLDFARAWVEFPDPADDEQVFRCDLTWLTSRWNCIFGSGCQGIQAGRADDGCCTLGAHFSDEDDEKRVAEHVARLTPDIWQHHDEGTANGWVSEDEDGDRQTRPFQGSCIFQNRPGFAGGQGCSLHILALREGREPLETKPDVCWQLPVRRTYDWIDRPDDTRVLQVSIGEYDRRGWGPGGHDLHWWCTSATSAHGAGDPVYVSYRPELIELMGKAGYDRLVELCEERLASQLPLLAPHPADPAGPTSPTTPAV
>NZ_CP041168.1|WP_141206326.1|5259073_5260015_+|Ppx/GppA-family-phosphatase
MRLGVLDVGSNTVHLLVVDAHPGARPLPAHSHKAELRLAQLLDGAGAIGSEGVEKLVSVVKDALQAAEDKGVEDLLPFATSAVREASNADDVLARVRAETGVELQVLSGAEEARLTFLAARRWFGWSAGKLLCLDIGGGSLEIAYGIDEEPDAAVSLPLGAGRLTAGWLPGDPPDPDDIRALRRHVRAQIARTVGEFARFGAPDHVVATSKTFKQLARLAGAARSAEGLYVQRELKRESLEAWVPRLAGMTTDQRAELPGVSEGRANQLLAGALVAEGAMDLFGVETVEICPWALREGVILRRLDHMGSAQGL
>NZ_CP041168.1|WP_030323816.1|5260131_5260956_+|sugar-phosphate-isomerase/epimerase
MAEPVVRIPDAKVALSTASVYPESTATAFEIAARLGYDGVEVMVWTDPVSQDIEALRRLSDYHGIPILAVHAPCLLITQRVWSTDPWVKLQRARAAAEKLGASTVVVHPPFRWQRQYARDFVDGIWRMANETDVRFAVENMYPWRYRDREMLAYAPDWDVTKDDYRHFTIDLSHAATSRTDAMQMVDRMGDRLGHVHLADGKGSAKDEHLVPGRGSQPCAELLERLALSGFDGHVVIEVNTRRAMSGAEREADLAEALAFTRLHLASPVKVPRR
>NZ_CP041168.1|WP_141206327.1|5260952_5261591_+|TetR-family-transcriptional-regulator
MSGAEGAPAVSDGTARKRGRPRRTESDAAGTRDRILVAAREEFSERGYEKTSVRGIAKAAGVDSALVHHYFGTKEQVFAASIEVAFAPALNASDTVAEGPLDGVGERLTRFIFGIWENPTTRTPLLAIVRSAVNNETAAAVFRRMVASQLLRRIAAQVDAPDAELRAELAAAQLIGTAMLRYVIKVEPLASADPEQIIARVAPVVQGHLTGA
>NZ_CP041168.1|WP_141206328.1|5261802_5263656_+|dihydroxy-acid-dehydratase
MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPIIAVANSFTEFVPGHTHLQPVGRIVSEAIVEAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICISNCDKITPGMLNAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISDEDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARKQLYVDAANTVMDITRRYYEQDDETVLPRNVATFAAFENAMALDIAMGGSTNTILHLLAAAQEAGVPFGLEEINEVSRRVPCLAKVAPNVAKNRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHSVHSPSLADWLKTWDVRGGSPSPKAVELWHAAPGCVRSAEAFSQSERWEALDEDAAEGCIRSAEHAYSKDGGLAVLKGNLAVDGCVVKTAGVDESIWRFEGPAVVCESQEEAVQKILTQQVKEGDVVVIRYEGPKGGPGMQEMLYPTSYLKGRGLGKACALVTDGRFSGGTSGLSIGHASPEAAAGGTIALVEDGDRIRIDIPARTIELLVDDEELARRDAALGGVYAPKNRERKVSAALRAYAAMATSADKGAVRDVSKLG
>NZ_CP041168.1|WP_141206329.1|5263714_5265808_-|PQQ-binding-like-beta-propeller-repeat-protein
MAPQGNTGAGAEAELPEYAGHYRLESHLGSGGMGVVHVAQSTSGMKLAVKIVHAEFAKDDEFRGRFRQEVAAARKVSGAFTASVVDADPDAERPWMATLFIPGPTLSDEVKRNGPLEPAQLRRLMAGLAEALRDIHRVGVVHRDLKPSNVLLAEDGPKVIDFGISRPKDSELRTETGKLIGTPPFMAPEQFRRPREVGPAADIFALGSVMVHAATGRGPFDSDSPYVVAYQVVHDEPDLTGVPANLAPLIVRCLAKEPEDRPTPDELMRELRSVAASYDTQAFIPAQRGEGVPEPRPRKETVRPRRRPSGKAALVAGAVVLVLAGVLASVQWLGDGVGAVAKSGDEPTATASAFAGWARNPVPKATGAAQCSYGATQVLCAQPGVVFALDPADGALLWRHPVAESKPGKPPAVVGGLVQPMVDEGRRLEALDPASGKARWRRPLPAHHGMQLAGGTLLLTLLDGTVTGVDASTGDTRWSGRVPEQPMPTFVSFAGDPLAYATNLSADASTTQVTAVDPATGAVRWEARLSGNVTPVGVRDGSVFFLSTNEVYGDTDAVVRYTPATRSTRRVKLPVARPDAQATVHGNTVYVLATSGALDAVDMEAGKRLWNLETSVSRGSVPVADGRHVYFTTADGRLFAVEADDGRLVGQTPARLGSNSGTVAAALPRPVLAAHRIYATAPDGTVFAVDARDPSAW
>NZ_CP041168.1|WP_141206330.1|5265990_5266308_+|SH3-domain-containing-protein
MSVERVEEAGAVETAEARTATASVRYYSVAPGVRLNVRSGPGTGYSVVRVLPEGSKVPIYCQTPGTSVAGPYGTSNIWDNVSNGQYVSDAYVLTGSDGYVADRCS
>NZ_CP041168.1|WP_141206331.1|5266326_5266662_+|SH3-domain-containing-protein
MTSLKRRSVALAGLACAFLMVGAAHAEATVHYFDTAPGQRLNVRRGPGTQYGIVRVLPEGAKVAIYCQTPGETVTGYYGTSNIWDNIANGEFVSDTNVKTGSDGYIASRCG
>NZ_CP041168.1|WP_141206332.1|5266716_5267226_+|EamA/RhaT-family-transporter
MSDESGTQDIPAGSPEGGPRPEPIRFFGTTWVDHDHGYALRRAGVAAGSLAAAVASCLILRFAYEGLQIADTGSFVTVLVIAMFAICSALAFRNTWDGFGRRPDPDRQASLRGLLAIGFVGSLLAYFLRSLTEAPGEKLHREEYESARRQHEKRSTRRTGNPSKKKRPR
>NZ_CP041168.1|WP_141206333.1|5267571_5268351_+|methyltransferase-domain-containing-protein
MTASSHTSRAHSFNAAAAQYAAHRPSYPPALFDAIEELSGRTLAGARVVDVGAGTGIATTLLHDRGAEVLAVEPGDGMAAQFRRLHPELPIVRGDGNDLPLLTDSVDFVTYAQSWHWTDTARAVPEALRVLRPGGSLVLWWNTHALDVPWIVGQFDRIAEHFKDYGAKPAAAAKDTRPRSLLADPTGRLDFAHRVVRWSRRVSLDAHLANIASHSIFLVAGEEHSGAFLTEERRILQEVFPDGTVEETYDVELLVATAG

Crispr_ID: NZ_CP041168_7

• CRISPR_ID: NZ_CP041168_7
• CRISPR_location: 6034807-6034899
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_7

Consensus_repeat	Method
GTGCAGGCGCAGTACTGACGTCT	CRISPRCasFinder

spacers of NZ_CP041168_7

>7.1|6034830|47|NZ_CP041168|CRISPRCasFinder
TGGCCGGAGCGAGTGCGGGCGCAGTACTGACGTCTTGGTCCGAGTAC

CRISPR arrays and Neighbor proteins around NZ_CP041168_7

CRISPR arrays

The CRISPR arrays of NZ_CP041168_7

>merge|NZ_CP041168|7|6034807-6034899|CRISPRCasFinder
GTGCAGGCGCAGTACTGACGTCTTGGCCGGAGCGAGTGCGGGCGCAGTACTGACGTCTTGGTCCGAGTACGTGCGGGCGCAGTACTGACGTCT

>NZ_CP041168|7|7|6034807-6034899|CRISPRCasFinder
GTGCAGGCGCAGTACTGACGTCT	TGGCCGGAGCGAGTGCGGGCGCAGTACTGACGTCTTGGTCCGAGTAC
GTGCGGGCGCAGTACTGACGTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141206838.1|6042128_6043184_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP041168.1|WP_141206828.1|6025962_6026709_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_062024014.1|6030988_6031630_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206834.1|6036025_6038488_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_CP041168.1|WP_028809477.1|6038976_6039723_+|hypothetical-protein	unknown	unknown	gnl|CDD|205967
NZ_CP041168.1|WP_141206835.1|6038429_6038843_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206829.1|6026757_6027270_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_030320648.1|6027280_6028399_-|magnesium-and-cobalt-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
NZ_CP041168.1|WP_020136747.1|6033582_6033735_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206832.1|6031925_6032783_+|PHP-domain-containing-protein	unknown	unknown	gnl|CDD|223686
NZ_CP041168.1|WP_141206831.1|6029581_6030805_-|MFS-transporter	unknown	unknown	gnl|CDD|341027
NZ_CP041168.1|WP_020136748.1|6032831_6033437_+|MarC-family-protein	unknown	unknown	gnl|CDD|225006
NZ_CP041168.1|WP_020136741.1|6040439_6040667_-|DUF3107-domain-containing-protein	unknown	unknown	gnl|CDD|378634
NZ_CP041168.1|WP_028809475.1|6040854_6041496_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP041168.1|WP_141206837.1|6041691_6041910_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_120051066.1|6024482_6025760_-|magnesium-transporter	unknown	unknown	gnl|CDD|225148
NZ_CP041168.1|WP_141206836.1|6039989_6040259_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206839.1|6043192_6044764_+|DUF3152-domain-containing-protein	unknown	unknown	gnl|CDD|371483
NZ_CP041168.1|WP_141206830.1|6028917_6029502_+|suppressor-of-fused-domain-protein	unknown	unknown	gnl|CDD|377450
NZ_CP041168.1|WP_141206840.1|6045084_6046803_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141206838.1|6042128_6043184_+|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.2674e-29
NZ_CP041168.1|WP_020136741.1|6040439_6040667_-|DUF3107-domain-containing-protein	gnl|CDD|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	1.44579e-36
NZ_CP041168.1|WP_141206834.1|6036025_6038488_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	4.59735e-131
NZ_CP041168.1|WP_028809477.1|6038976_6039723_+|hypothetical-protein	gnl|CDD|205967	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like.	8.28413e-95
NZ_CP041168.1|WP_141206830.1|6028917_6029502_+|suppressor-of-fused-domain-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	2.78536e-30
NZ_CP041168.1|WP_030320648.1|6027280_6028399_-|magnesium-and-cobalt-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.96116e-165
NZ_CP041168.1|WP_120051066.1|6024482_6025760_-|magnesium-transporter	gnl|CDD|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	8.48075e-45
NZ_CP041168.1|WP_141206831.1|6029581_6030805_-|MFS-transporter	gnl|CDD|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.92983e-92
NZ_CP041168.1|WP_020136748.1|6032831_6033437_+|MarC-family-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	5.04786e-41
NZ_CP041168.1|WP_141206839.1|6043192_6044764_+|DUF3152-domain-containing-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.51361e-72
NZ_CP041168.1|WP_028809475.1|6040854_6041496_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.01065e-16
NZ_CP041168.1|WP_141206832.1|6031925_6032783_+|PHP-domain-containing-protein	gnl|CDD|223686	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only].	9.17476e-46
NZ_CP041168.1|WP_141206840.1|6045084_6046803_+|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0

Protein sequences

>NZ_CP041168.1|WP_020136747.1|6033582_6033735_-|hypothetical-protein
MRFEIMRLDDVDGTPVDSTVVDAASVNRIVQQAAAIGQRLWIRPADTTAS
>NZ_CP041168.1|WP_020136748.1|6032831_6033437_+|MarC-family-protein
MFDVAVFGSLFLTLFVIMDPPGITPIFLALTAGRPGKVQKRMAFQAVCVAGGVIAVFGLLGHQILDYLHVSVPALMIAGGLLLLLIALDLLTGKTDEPKQTKDVNVALVPLGMPLLAGPGAIVSVILAVQKADSVATQVSVWVAILAIHVVLWLVMRYSLLIIRVIKDGGVVLVTRLAGMMLSAIAVQQIINGITQVVRAS
>NZ_CP041168.1|WP_141206832.1|6031925_6032783_+|PHP-domain-containing-protein
MRIDLHTHSTASDGTDTPAELVRNAAAAGLDVVALTDHDTTRGHREALAALPAGLTLVTGAELSCRIDGISLHMLAYLFDPEEPALLAERELVRDDRVPRARAIVARLQEIGVPVTWEQVARIAGDGSVGRPHVATALVELGVVSSVDEAFTADWLGDGGRAHVAKHETDPFEAIRLVKAAGGVTVFAHPGASKRGRTVPESAIAEMAAAGLDGIEIDHMDHDEETRVRLRGLAADLGLLVTGSSDYHGSRKTVALGAYTTDPEVYGEITRRATGAFPVPGTGGV
>NZ_CP041168.1|WP_062024014.1|6030988_6031630_+|hypothetical-protein
MRGEPSCPKCGGRVRAPGLFADSWQCDVHGTVHPLQPVIPPSVEALGVVVHRTQVPVWMPWPLPVGWLFTGVACAGDDRSGGRATAVACTGPGPLGGVGELILVAEELGVGLGARYAGIDGPDPGPYMSVEKPAQAKVLAAGRPTPLWHVAGVPDDRAVFAGEALGLWLWAVVWPEQSGLLMYDELVLTDLRDAGAELELVPCGALSPRLLKP
>NZ_CP041168.1|WP_141206831.1|6029581_6030805_-|MFS-transporter
MDPFDAGAGGILRQPKAVWATAGASVVAFMGIGLVDPILPSIAKGLDATASQVSLLFTSYFLITAIAMLVTGFVSSRIGGRKTLLLGLALVVVFAGLAGTSGSVGELVGFRAGWGLGNALFVSTALAVIVGAAAGGSAAAILLYESALGLGMACGPLLGALLGDASWRYPFFGTAFLMAIGFLCITVFLKEQPKPARKTSLLDPLKALGHGGLASAAVSSFFYNYTFFTVLAFTPFVLDMTPYKSGAVFFAWGVLLAVFSVFVAPRLQERFGSLKVLGGSLVLLAADVLVLGYGNHTAAVVCTILSGAFIGVNNTVYTELALGVSDAPRPVASAGYNFVRWFAAAAAPYFAPKIEEWTDIHIPFVVAAVTAVLGALVVVVRRKALTHEAEELEPRHAVEDSVTVFAG
>NZ_CP041168.1|WP_141206830.1|6028917_6029502_+|suppressor-of-fused-domain-protein
MADVLPLVEARLRGALGEPDARAAVTFLGTDRIEVLRFTDGDVVRYATLGMSAQPMSDPTAMLADPVKGPRAELVLSVRAGLADTDKVLRPLAVLAASPQVEGVVVAPGASLDVGEPLWPGAPFTSVLVAEPGGLVEDLELDEPLDPVHFLPLLPMTPNEAAWKRVHGAQALQERWLTHGTDLRDPSRKSVPLD
>NZ_CP041168.1|WP_030320648.1|6027280_6028399_-|magnesium-and-cobalt-transport-protein-CorA
MSMIRDLRAAVRPSRPSLRKDTGAYDATRDPSTPSAVVDCAVYRDGRRVETDCQLSPHDAMRQVRRDGGFVWIGLHEPSEAEFSGIASEFGLHPLAVEDAVQAHQRPKLERYDDSLFTVFKTIHYVEHDELTANSEIVETGEVMCFTGRDFFITVRHGGQGSLRALRHRLQDDPELLAKGPSAVLHSIADHVVDGYVAVADAVQDDIDEVETEVFTPGRGGKVSRGVDSARIYQLKREVLEFKRAVAPLLRPMQLLSERPMRLVDPDIQKYFRDVADHLVRVQEQVLGFDELLNSILQANLAQASVAQNEDMRKITSWAAIVAVPTMVCGVYGMNFDYMPETHWRFGYPVIMAITGVICMGIHRTLKRNGWL
>NZ_CP041168.1|WP_141206829.1|6026757_6027270_-|hypothetical-protein
MTSELLDRALVEEATKKSGLVWVQGPGAPARALWHVWHEGAACLVGDGPGEQPLPGLVDSGTAEVTVRSKDKGGRLVSWAARVVELAPGSEAWEAAVGELKGKRLNAPDGEAMTDRWARECRVLRLEPTGVVGSLPDGDLAEPPLPTPATTREPIPAGLPRLLLKKRKRG
>NZ_CP041168.1|WP_141206828.1|6025962_6026709_+|hypothetical-protein
MTAIARDRTRRTVLAGAVCALVVTGTGLTGCSEDPDAGTNGVGKLPAEQIQAKTRAAAGAADALRLSGNVVTSGRTYKLDMRLSSAGGSGSVTAEGATFQLLRIGEKLYLKADAGFWAQEDGKGDDTDAAADKLDGKYVKVPSGDPAYKKFSGFTDKDVLLDGLLTLHGSLDTDGHHEQAGTRTIRITGDKGDGGTLDVSLEGQPYPLRLARAGGAGTLTFSAWGKDFPLTEPAKDETVDYGKQLPTS
>NZ_CP041168.1|WP_120051066.1|6024482_6025760_-|magnesium-transporter
MAAGAPRIFVSHLAGVAVFDPNGDQVGRVRDLVVVLRVGRRPPRVLGLVVELSTRRRIFLPMTRVTSIESGQVITTGVLNVRRFEQRPTERLVFGELLDRRVTLVESDEQVTVLDISVQQLPARRDWEIDRVFVRKGGKGGAFRRKGEALTVEWSAVTGFTLEEQGQGAESLLATFEQLRAADLANVLHHLSAKRRAEVAAALDDDRLADVLEELPEDDQIEILGKLKEERAADVLEAMDPDDAADLLSELPTEEQERLLSLMQPGDAADMRRLMAYEEHTAGGLMTTEPIVLRPDATVADALARVRNPDLSPALAAQVYVCRAPDETPTGKYLGTVHFQRLLRDPPYTLVSSLVDDDLQALDPDATLPVIAGFFATYDMVAAPVVDDSGSLLGAVTVDDVLDHMLPEDWRETEFDAEGAAHHDA
>NZ_CP041168.1|WP_141206834.1|6036025_6038488_-|DEAD/DEAH-box-helicase
MTLPVALSGTDVIGQAKTGTGKTLGFGLPLLERVTVPADVEAGRAKPEDLTDAPQALVVVPTRELCTQVTNDLLTAGKVRNVRVLAIYGGRAYEPQVEALKKGVDVVVGTPGRLLDLAGQKKLNLGHIKALVLDEADEMLDLGFLPDVEKIINLLPARRQTMLFSATMPGAVIGLARRYMSQPTHIRATAPDDEGKTVANTAQFVYRAHNMDKPEMVARILQSDGRGLAMVFCRTKRTAADLADQLKQRGFAAGAVHGDLGQGAREQALRAFRNGKVDVLVCTDVAARGIDVEGVTHVINYQSPEEEKTYLHRIGRTGRAGAKGIAITLVDWDDIPRWQLINKALELNFNDPPETYSTSPHFYEELNIPAGTKGILPRAERTRAGLDAEELEDLGEPGGRGARGRGDRDRGRGRGGRDESRSADRERSERTPRRRRRTRGGSALDTTAPAEAVAPSESGVSAPASPTEDVTAPRTPRRRRRTRGGAADSAPATASTAAVTAEPAVSEAAEAAVTTAESTSLDTETPAKPRRRRTRKSAEAPVEQAQATVAETAPVAEVVAETPAAKPRRTRKSAAVAPAADAAEVAVDTAEATEAKPRRRTRKAAEPAVAAVTAVETVEAPKVTEAADVTEVAETKPRRTRKTTAAAPAETATVEAAEAVVEAKPRRTRKTAASKAAEAAVDTVEATEATPRRRTRKAAEPDVAAEIPVQTVQEAEVAEAVKPRRTRKTAASKAAEAAEAAVDTAEGTATTPRRRTRKTAAAAPAETATAEVAEAKPRRRTTRKAAEPAVTADIPAQADQEPAAPRRRTRKTAAAEPADS
>NZ_CP041168.1|WP_141206835.1|6038429_6038843_+|hypothetical-protein
MPVLAWPMTSVPERATGSVISWMGNGLTMPTASRASAVSVRIPRSRKVVVRVLPLLCARCEASAGGRHNRAGDVGCLTGEAVMARDHCRRSSARTAEGPPPNSVRTVPYGRGGLSGRSRSGHRPGILIRAACRGTAH
>NZ_CP041168.1|WP_028809477.1|6038976_6039723_+|hypothetical-protein
MRFMTTPDNTSDAPAERTGVAAQDWAQAATEPQYRAAVVDLLGALAYGELAAFERLAEDAKLAPTLADKAELAKMASAEFHHYEKLRDRLAEIGEEPTLAMEPFVAALDGFHRQTAPSDWLEGLVKAYVGDSIASDFYREVAERLDTDTRELVLAVLDDTGHAGFAVEKVRAAIDAEPRVGGRLALWARRLMGEALSQSQRVVADRDALSTMLVGGVADGFDLAEVGRMFSRITEAHTKRMAALGLAA
>NZ_CP041168.1|WP_141206836.1|6039989_6040259_-|hypothetical-protein
MMLFEALGSALLGLVLAGVALRRLSHRLPTRSLVLATGPAGALFGAFVTHTALDPGNVLLILLGAAVVSVASLSLLLRPSGRLRRSATA
>NZ_CP041168.1|WP_020136741.1|6040439_6040667_-|DUF3107-domain-containing-protein
MEVKIGVQHAPREIVLESGQSAEDVERAVADALAGKSQLLSLVDEHGRKVLVPADRLAYVELGEPAPRKVGFGAL
>NZ_CP041168.1|WP_028809475.1|6040854_6041496_-|TetR/AcrR-family-transcriptional-regulator
MTAIEQTEAARPRGTRLPRRARRNQLLGAAQEVFVAQGYHAAAMDDIAERAGVSKPVLYQHFPGKLDLYLALLDQHCESLIQAVRSALASTTDNKQRVRATMDAYFAYVEDDGGAFRLVFESDLTNEPAVRERVDKVTNECAEAIRDVIAEDTGLSPAEAMLLASGLGGLAQVVARSWLHSDRSVPRDQAVQLLTSLAWRGIAGFPLHGTDHH
>NZ_CP041168.1|WP_141206837.1|6041691_6041910_-|hypothetical-protein
MAYDPTDPEAFEEESEAVELDVEAPEVDAAEQHTDIAPDHDDPLTGVDPGRASEADLIEQARVVSLDEDDYR
>NZ_CP041168.1|WP_141206838.1|6042128_6043184_+|alpha/beta-fold-hydrolase
MSSTEVPFVPPANVLPKVSPVRVGEGERLRSVGLQGITLTVRSRPPAREGLPPALYVHGLGGSSQNWSALMEQLEGDVDGEALDLPGFGDSPPPDDGNYSLTAHARAVIRFLDASGRGPVHLFGNSLGGAVSTRVAAVRPDLVRTLTLVSPALPEIRVQRTAVPTGLLALPGVAGLFTRYSKNWTAEQRVRGVTALCYGDPGRVTPEGFRHAVEEMERRLQLPYFWDAMARSARGLVNAYTLGGQHALWRQAERVLAPTLLVYGGKDQLVGFRMAQKAARAFRDSRLLTLPEAGHVAMMEYPETVAGAFRDFVSDKGESTSGGAGPVRGSAGRSEAGTASGGGADATAVGS
>NZ_CP041168.1|WP_141206839.1|6043192_6044764_+|DUF3152-domain-containing-protein
MGRHSRRGPAPKKGSDNSGSSDGDRAVQTGPGPVPGAGTEVPGGRARNLSQAGTPAPGGTGRRVPAQGGPRLPEGTPAHGFPRLPEGTPARGLPRLPDGTPAHGFPRIADGTPAQGTPRARGGHPEQRESGGGWGAFDGRGPGAQAAGGPGGVLPRQRQGQRQQAAGTRQGPRQDYLDAFTDDTDLFAPGAPKGRPGRGQREGHGPRPGAGTSVAAHPSDPYGSYGSVTDWPDDTSGGVATGAGSDGTPPVDAPPSAKGGKGRTFTGVAAAAVVTVLAVVVAGQVTGERDTAAGSSAATDQARDARDTVTAGRPTPSGSPSVATLTYEQAMGTKYPLSAKLDGSGKFDAVPGVDKAPGKGQKYTYRVDVEQGLGLDGALFAEAVQKTLNDDRSWAHGGARTFERVYTGKPDFVITLASPGTTADWCAKSGLDTTEDNVSCDSAATERVMINAYRWAQGSITYGDRIHAYRQMLINHEVGHRLGYSHVTCDKNGELAPVMQQQTKFLDHDGIHCRPNPWPYPGS
>NZ_CP041168.1|WP_141206840.1|6045084_6046803_+|ABC-transporter-substrate-binding-protein
MRQPSLTKRRVAALSVSLVLAAGAAACGPEDNDAKSSGGDSAPHKGGTLTVLNSDPQSDFDPARLYTSGGGNVPSLVFRTLTTRNRESGAEGTKVVPDLATDTGRPNKDATVWTYTLKKGLKYEDGTAITSADIKYGIERSFAPELSGGAPYLRDWLVGAADYQGPYKDKKGLPAIETPDARTIVFHLNKPEGEFPYLATQTQFTPVPKAKDTGTKYEEHPVSSGPYKVVKNENDGETLLLERNTYWSAATDPERKAYPDKIDVKSGLDSSVINQRLSASQGADAAAVTTDTNLGPAELAKVTGDKELAARVGTGHFGYTNYIAFNPTVKPFNDVKVRQAISYAVDRSSVVNAAGGSSLAEAATTFLPDQKSFGYEPYDLFPAGATGNAAKAKELLKEAGHPNGLTVTLTHDNAQNFKTSPEIATAIQDALKKAGITVKLQGLEDNNYSDTIHDVKKEPGFFLSAWGADWPSGGPFLAPIFDGRQIVKDGANFNSGLLNDKSVNAEIDAINKLTDLDAAAKRWGALDKKIGEQALTVPLFHPVYKRLVGKDIRNVVISDWTGVLDISQVAVK

Crispr_ID: NZ_CP041168_8

• CRISPR_ID: NZ_CP041168_8
• CRISPR_location: 6070337-6070463
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP041168_8

Consensus_repeat	Method
GACGACGAGGCGCCCTACGAGGACG	CRISPRCasFinder

spacers of NZ_CP041168_8

>8.1|6070362|20|NZ_CP041168|CRISPRCasFinder
CGGACTGGCCCCCGCCGCCG
>8.2|6070407|32|NZ_CP041168|CRISPRCasFinder
ACGAGGCGCCTTACGACGACGAGGCGCCCTAC

CRISPR arrays and Neighbor proteins around NZ_CP041168_8

CRISPR arrays

The CRISPR arrays of NZ_CP041168_8

>merge|NZ_CP041168|8|6070337-6070463|CRISPRCasFinder
CACGACCCGGACACCTACGACGACCCGGACTGGCCCCCGCCGCCGGACGACGAGGCGCCCTACGAGGACGACGAGGCGCCTTACGACGACGAGGCGCCCTACGACGACGAGGCGCCCTACGACGACG

>NZ_CP041168|8|8|6070337-6070463|CRISPRCasFinder
CACGACCCGGACACCTACGACGACC	CGGACTGGCCCCCGCCGCCG
GACGACGAGGCGCCCTACGAGGACG	ACGAGGCGCCTTACGACGACGAGGCGCCCTAC
GACGACGAGGCGCCCTACGACGACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_028809468.1|6077268_6077637_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP041168.1|WP_141206854.1|6077633_6077960_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_079069728.1|6076771_6077095_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206844.1|6050711_6052481_+|DUF3492-domain-containing-protein	unknown	unknown	gnl|CDD|340841
NZ_CP041168.1|WP_141206856.1|6078288_6079659_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|270872
NZ_CP041168.1|WP_020136729.1|6055268_6056018_+|hypothetical-protein	unknown	unknown	gnl|CDD|371915
NZ_CP041168.1|WP_141206855.1|6078063_6078282_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141206845.1|6052477_6053848_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141209435.1|6074463_6076602_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|223288
NZ_CP041168.1|WP_141206852.1|6071414_6072824_+|dipeptidase	unknown	unknown	gnl|CDD|349929
NZ_CP041168.1|WP_141206853.1|6072920_6073865_+|NAD(+)-diphosphatase	unknown	unknown	gnl|CDD|225373
NZ_CP041168.1|WP_141209436.1|6079651_6080869_-|TOMM-precursor-leader-peptide-binding-protein	unknown	unknown	gnl|CDD|366360
NZ_CP041168.1|WP_020136719.1|6073956_6074199_-|mycoredoxin	unknown	unknown	gnl|CDD|131255
NZ_CP041168.1|WP_062024032.1|6056081_6057260_+|adenylyltransferase/sulfurtransferase-MoeZ	unknown	unknown	gnl|CDD|181156
NZ_CP041168.1|WP_141206848.1|6060621_6063345_-|TIGR00374-family-protein	unknown	unknown	gnl|CDD|377103
NZ_CP041168.1|WP_030320602.1|6054321_6055281_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|366597
NZ_CP041168.1|WP_141206849.1|6063531_6063918_+|DNA-binding-protein	unknown	unknown	gnl|CDD|226219
NZ_CP041168.1|WP_141206846.1|6057331_6058879_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP041168.1|WP_141206847.1|6059007_6060552_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP041168.1|WP_141206850.1|6064184_6067685_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|223288

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_028809468.1|6077268_6077637_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	5.35639e-16
NZ_CP041168.1|WP_141206856.1|6078288_6079659_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|270872	cd13970, ABC1_ADCK3, Activator of bc1 complex (ABC1) kinases, also called aarF domain containing kinase 3. This subfamily is composed of the atypical yeast protein kinase Abc1p, its human homolog ADCK3 (also called CABC1), and similar proteins. Abc1p (also called Coq8p) is required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. It is necessary for the formation of a multi-subunit Q-biosynthetic complex and may also function in the regulation of Q synthesis. Human ADCK3 is able to rescue defects in Q synthesis and the phosphorylation state of Coq proteins in yeast Abc1 (or Coq8) mutants. Mutations in ADCK3 cause progressive cerebellar ataxia and atrophy due to Q10 deficiency. In algae and higher plants, ABC1 kinases have proliferated to more than 15 subfamilies, most of which are located in plastids or mitochondria. Subfamily 13 (ABC1K13) of plant ABC1 kinases belongs in this subfamily with yeast Abc1p and human ADCK3. ABC1 kinases are not related to the ATP-binding cassette (ABC) membrane transporter family.	4.16437e-96
NZ_CP041168.1|WP_141206844.1|6050711_6052481_+|DUF3492-domain-containing-protein	gnl|CDD|340841	cd03813, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.	1.47422e-173
NZ_CP041168.1|WP_020136729.1|6055268_6056018_+|hypothetical-protein	gnl|CDD|371915	pfam12138, Spherulin4, Spherulation-specific family 4. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.	5.09704e-24
NZ_CP041168.1|WP_141209435.1|6074463_6076602_+|AAA-family-ATPase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	3.15971e-112
NZ_CP041168.1|WP_141206852.1|6071414_6072824_+|dipeptidase	gnl|CDD|349929	cd05680, M20_dipept_like, uncharacterized M20 dipeptidase. Peptidase M20 family, unknown dipeptidase-like subfamily (inferred by homology to be dipeptidases). M20 dipeptidases include a large variety of bacterial enzymes including cytosolic nonspecific dipeptidase (CNDP), Xaa-methyl-His dipeptidase (anserinase),and canosinase. These dipeptidases have been shown to act on a wide range of dipeptides, but not larger peptides. For example, anserinase mainly catalyzes the hydrolysis of N-alpha-acetylhistidine while carnosinase degrades beta-alanyl-L-histidine.	0
NZ_CP041168.1|WP_141206853.1|6072920_6073865_+|NAD(+)-diphosphatase	gnl|CDD|225373	COG2816, NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair].	2.26439e-86
NZ_CP041168.1|WP_141209436.1|6079651_6080869_-|TOMM-precursor-leader-peptide-binding-protein	gnl|CDD|366360	pfam00899, ThiF, ThiF family. This domain is found in ubiquitin activating E1 family and members of the bacterial ThiF/MoeB/HesA family. It is repeated in Ubiquitin-activating enzyme E1.	9.99437e-26
NZ_CP041168.1|WP_020136719.1|6073956_6074199_-|mycoredoxin	gnl|CDD|131255	TIGR02200, conserved_hypothetical_protein, Glutaredoxin-like protein. This family of glutaredoxin-like proteins is limited to the Actinobacteria and contains the conserved CxxC motif.	2.1339e-33
NZ_CP041168.1|WP_062024032.1|6056081_6057260_+|adenylyltransferase/sulfurtransferase-MoeZ	gnl|CDD|181156	PRK07878, PRK07878, molybdopterin biosynthesis-like protein MoeZ; Validated.	0
NZ_CP041168.1|WP_141206848.1|6060621_6063345_-|TIGR00374-family-protein	gnl|CDD|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.59009e-29
NZ_CP041168.1|WP_030320602.1|6054321_6055281_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|366597	pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilize NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.	4.2822e-40
NZ_CP041168.1|WP_141206849.1|6063531_6063918_+|DNA-binding-protein	gnl|CDD|226219	COG3695, COG3695, Predicted methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	6.45904e-18
NZ_CP041168.1|WP_141206846.1|6057331_6058879_-|alpha/beta-fold-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	1.09672e-35
NZ_CP041168.1|WP_141206847.1|6059007_6060552_-|alpha/beta-fold-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	1.35491e-35
NZ_CP041168.1|WP_141206850.1|6064184_6067685_+|AAA-family-ATPase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	6.8042e-71

Protein sequences

>NZ_CP041168.1|WP_141206850.1|6064184_6067685_+|AAA-family-ATPase
MSSSSSTKHPSHAQVRQGARGAYRLVRTPPARVDPPHLDAAQRAVVEHRSGPLLVLAGPGTGKTTTLVESVASRIARGGDPARVLVLTFSRKAAVELRDRMALRVGAARAPQATTFHSFCYALVRAHQDSDLFVEPLRLLSGPEQDVTVRELLAGQPDLERLGLAHVRWPDELRACLTTRGFADEVRAVLARSRELGLGPGALDAFARRIGRPDWRAAAAFLAEYLDVLDLQGVLDYAELVHRAVLLARRPEVAEQLAAQYDAVLVDEYQDTDPAQVRLLDALAGGGRTLVAFGDPDQSIYAFRGADVNGILDFPYAFPRADGRPAPVEVLRTSRRSGAALLAATRLVTQRMPLTRLPAEKVRAHRELAPVREGGRVEVFTYPTPGTELDNIADILRRAHLEDGVPWGEMAVLVRAGSRTIPTVRRALTAAGVPLDIDGDDLALRHEPAVAPLLTALRAVATAEAAEGAVRHQEAASEEAAPEGPAPEGPVREETEPSEETASEEAAPEDPAPEHPVAEETEPSDQQGAAGEPASEAPASVTSWLDTETALTLLASPLAGMDAADLRRLGRALRDEERAGGNAFPPPSDELLARALAEPERLAAHDPAYARGAQRLGALLGKARARLAGGGSAEEALWDLWDGTPWPGRLERAARRGGAAGRNADRDLDAVCALFATAARAEERTGGRGALNFLEEIDAEDIAADTLTRRAVRPDAVRLMTAHRSKGLQWRLVVVAGVQEGLWPDLRRRGSLLEADRIGRDGLAEPLTPGALLAEERRLFYVAATRARERLVVTAVKAPADDGDQPSRFLTELGVEPKDVTGRPRRPLSVSALVAELRATTVDPRVSDTLREAAARRLARLAALADDDGRPLVPSAHPYRWWGMFEPTESKVPLRNRDQPVVLSGSALDQLANTCALQWFLGREVKADAPATVAQGFGNVVHVLADEVASGRTPADLDVLMERLDSVWNALAFDAPWKSAQEKENARVALERFLKWHVMDRTGRTPVASEHDFDVTLEAGEVEVRIRGQMDRVEADGEGRAYVVDFKTGKQPVSSADVERHPQLAVYQLAVREGAVDEAFDGVRPEPGGAELVQLRQGAPKRDGGETLPKVQAQDPLEGEWVGDLLATAAGKVLDERFTPSAGQHCAHCAFRASCSAQPEGRHVVE
>NZ_CP041168.1|WP_141206849.1|6063531_6063918_+|DNA-binding-protein
MSEQSLPRDAHPEYADTLPEYAERVLDVAERIPPGRVMTYGDVAEWLEEGGPRQVGRVMALYGSPVPWWRVVRADGVLLPGHELEALARYREEGTPLKGASRAAEGHLPRLDMRRARWDGDERAEGHT
>NZ_CP041168.1|WP_141206848.1|6060621_6063345_-|TIGR00374-family-protein
MKPQGVHPEDAESTSAASSRPDAADRDDDRTPGADAGVEAEETHAEEVEGDEPLLPARVHRPSDLMRLLVGVLAVVVLLAIAAFAHGTTSGLEQDINKGTGQAPDLLIKIAGLASSIAILLVPVAFAIERLIKRDGLRIADGVLAAVLAHGVTLATDLWVAKAAPDSIQEALTQPSPGDIHALTDPVHGYLAPVIAYMTAVGMSRRPRWRAVLWMVLTLDAFSMLVTGYTTPFSIILTVLIGWTVAYGTLYAVGSPNVRPTGQTLMAGLRTVGFHPAGAAREETPETAENGDRGRRYFVTLEDGPPLDVTVVDREQQAQGFFYRVWRNLTLRGFATRSSLQSLRQALEQEALLAYAAIAAGANAPKLIATSELGPDAVMLVYEHTGGRTLESLSEDEITDELLRNTWRQVQALQSRRIAHRRLAGDAILVDRSGSVILTDLRGGEIAASTLLLRMDVAQLVTTLGLLAGAERAVASGVEILGPDTVADCLPMLQPIALTRSTRATLRRLARERAQREREAVLEASRLAKQARLDEAAQDTGPVLDKPDKKAERAEARAEKRAIDEALEEAREEDLLSQIRNQVLLIRPQAPVEPARLERVRPRTLISVFAGAIGAYFLLTQLTHIEFGPLIENAEWGWVAAAVLFSACSYFAAAMALLGFVPERVGFLRTVAAQVAGSFVKIVAPAAVGGVALNTRFLQRQGVRPGLAVASVGASQLFGLGCHILMLLSFGYLTGTEKTPSLSPSRTVIAGLLTVAVLVLVVTSVPFLRKFVVTRVRSLFAGVVPRMLDVLQRPQKLVTGIGGMLLLTACFVMCLDASIRAFGQEGTSLSIASVAVVFLAGNALGSAAPTPGGVGAVEATLTVGLIAVGLPKEVAAPAVLLFRLLTLWLPVLPGWLAFNHLSRKGAL
>NZ_CP041168.1|WP_141206847.1|6059007_6060552_-|alpha/beta-fold-hydrolase
MPNPARPRVAALTAAALLLSCALAGCGGDSQDEDLSAQKLSWKDCRAPSRAEGGGDAPSPLPGGTEWQCATLKAPRDWAKPKGDTIDLALIRARTSGPKDKRIGSLVFNFGGPGGSGVTTLPAFGTEYAKLRTRYDLVSFDPRGVGRSAPVECLNDPQLDYYFEQDWTPDDSAERTALLNNTKEFNAACEDNSKKMLPHVRTTDAARDMDLMRQVLGDDKLYYFGISYGTELGGVYAHLFPRHVGRAVFDAVVDPTQNSEQGSLGQAEGFQLALDNFAEDCTSKTEDCPVGDTAQDVKDRIAKLLADLDRKPIPGIGQRPLTQTAATNGIAQSLYSKDFWEYLVEGLQQAYDGDGRILMLLSDSLNGRSENGEYSNITAANIAINCADDKPRYTAADVERGLPEFRAASPLFGDFLAWSMVSCTDWAVPGAADHPDVSAAGSAPILVVGNTGDPATPYEGARRMVEALGPGVGVELTYKGQGHGAYGSKNSCVQRAVDGYLLNGRVPAAGTVCS
>NZ_CP041168.1|WP_141206846.1|6057331_6058879_-|alpha/beta-fold-hydrolase
MGRFARWAAVAATAALLATGCSGGSSGRGDGVERTGGATPATRGAKALPASLTSQQLDWGRCKATGDFSPPGNDWRCATLKTPLDWSKPDGETIGLALIRTKARGGDRVGSLLFDFGGPGLTGVGTLPAYAATASLLRERYDLVSWDPRGVGASEGVRCRGDKEVQAAESVDATPDTPAEERAYLRDATDFARGCEKDAGKLLAHVSTTDTARDMDLMRQVLGDDKLYYFGISYGTQLGGVYAHLFPHRVGRMVLDAAVDPSADAVGHRKNQARGFQRALDNYLKSTGQDPARGTRRIADLLERIDANPLPTFSGRKLTQVLAFTGIVYPLYRQDSWPSLTSALRTAEQGDGSELLALADGYNERDPSGHYGLLPQAQRVISCLDDKQRPTLAQAKRLLPEFERISPVFGPFLGWDAAGWCHDWPVAGQFETPEVSAPGAAPVLVVGNTGDPATPYEGARKMADELGKGVGVELTWEGQGHTAYGNGSDCVDSTVNAYLLKGTVPKDGKVCAQGQ
>NZ_CP041168.1|WP_062024032.1|6056081_6057260_+|adenylyltransferase/sulfurtransferase-MoeZ
MSLPPLVEPAAELTVDEVRRYSRHLIIPDVGMDGQKRLKNAKVLCVGAGGLGSPALMYLAAAGVGTLGIVEFDEVDESNLQRQIIHSQADIGRSKAESARDSVLGINPYVNVVLHEERLEADNVMDIFSQYDLIVDGTDNFATRYLVNDACVLLNKPYVWGSIYRFDGQASVFWSEHGPCYRCLYPEPPPPGMVPSCAEGGVLGVLCASIGSIQVTEAIKVLTGTGEPLVGRLMIYDALEMQYRQVKVRKDPNCAVCGENPTVTELIDYEAFCGVVSEEAQEAAAGSTITPKQLKEWIDDGENIEIIDVREINEYEIVSIPGAKLIPKNEFLMGTALESLPQDKKIVLHCKTGVRSAEVLAVLKSAGFSDAVHVGGGVIGWVNQIEPDKPVY
>NZ_CP041168.1|WP_020136729.1|6055268_6056018_+|hypothetical-protein
MPHLTSTKSSTPSTELHTGLGVPGFAHPLVAPAEWAELTRPGTPLHWTVLNIADGPGARPDPHCLEAAGRLRNAGVRVLGHLDTTYGARTFGELISEGQRYLDWYQVDGFLLDRCPTGRAALPEIRRAVTTLRALRDDAHIVFGHGTHPYPGYAENADQLITFSGPWSDYRWSQVAEWTADYPPETFCHLVHGLPGPHLEEALRIARWQGASTIWFTDRTDRGGRVDPWETMPGYWDEIVSRIGTGVSE
>NZ_CP041168.1|WP_030320602.1|6054321_6055281_+|NAD-dependent-epimerase/dehydratase-family-protein
MRVLLIGANGYLGRFVADRLLADPAVQLTALGRGDDADVRFDLASGSPGALTRFLDAVHPGVVVNCAGATRGGARELTRHNTVAVATVCEALRRSGCGARLVQIGCGAEYGPSQPGSSTAEDAVPRPGGPYGVSKLAATELVLGSGLDAVVLRVFSPAGPGTPAGSPLGRLAEAMRRAMQSGDGELKLGGLGAQRDFVDVRDVARAVHAASLSAAQGVINIGSGRAVRLRDAAAVLARVAGYGGALHELDGPPGPLRASIGHPRSESDHAAPVAYPYPDGCGSWQQADVRTARDRLGWRPRINLEESLADIWMEAACRI
>NZ_CP041168.1|WP_141206845.1|6052477_6053848_+|hypothetical-protein
MSDTDTTDTTGALGEQEVSDAGGELGEHEVSAVHGETGNPEAPADASPESAERPERAAPASSGQAAAEADAPTSPAPAPRAPEIATGRTFTTSSARRSAADPVKALMHRHRELCERAVDPLEIAAGLEAHGVTDRTAVRFRHRDVFSLAEEMYARTPRDGETPPSPAVDRTSPPRAAWALLTLLPGALCAAAVVGIRLTDGRSRLVTALVGALVISFAVRAALSRGPLGAPDRARTATPSTWTYWLLAYAAFGDGLLGAAVTGGPDALPTGAADAPWPVATAPLLALTLSCAPAAWAAHLLRARARRKLTASRGLEDFAASVRPLLIGTFALYLCALTALLALSAAALEEPAPYAQTLTLGALLLLARLLTTHGFTHAPVVVLIAATTAQATALATTFASRLPGCAFLATPVNALVDLWGAAGIQTLSCGIAALALLIHATRKLTRASAHAQEEPC
>NZ_CP041168.1|WP_141206844.1|6050711_6052481_+|DUF3492-domain-containing-protein
MRIGLLTEGGYPYVSGDARLWCDRLVRGLEQHEFDIYALSRSERQEDEGWVPLPPQVDRVITAPLWTAEDDGVVYGRRARRRFAESYGELAAALCEAGVAETSGPGSTGATGLVDSAKGSVKGSGEVSGVEADRFASALYGLAELARDEGGLVGALRSETAVRALERACRAPGARQTAREARVPDLLAVAAHLERALRPLSLDWYEDDGLGAVDLCHAASGGPAALPGLLAHHFCGVPLLVTEYGVRLRTHYLADSDSPPAVRALLAAFHGRLATETYRRAAVVTPGNTHARRWQERCGADREKIRTVYPGMEVGHFADVGESAECVDPDTLVWVGRVEPAKDLISLLHAFAEIRKEEPKTRLRIVGAPSGPEGAAYLGHCKALAAQLFPDEAEGLHSVGDNPVSFEEIGGPELPSAADAYGAGAVTVLSSVVEGFPISLVEAMFCARATVSTDVGAVVEVIGGTGLVVPPRNPKALAEACLTLLRDPERRERLGAAARARALELFTVEQNITAFHGIYLEIVSRTPVRRVVLDGTGEPLPFAAPAEAHVPGRWTERSTRVVARGGPGWAAGPPVRATPPFAATEGAPG
>NZ_CP041168.1|WP_141206852.1|6071414_6072824_+|dipeptidase
MTMSPTPDSAVRSYIQQHRAAFLDDLAEWLRIPSVSAQPDHGPDVRRSADWLAAKLRETGFPTAEVWETPGAPAVFAEWPAEDPGAPTVLVYGHHDVQPAAREDGWDSDPFEPVVRDDRLYARGAADDKGQVFFHTLGVRAHLAATGRTAPAVHLKLLIEGEEESGSPHFRALVEEHEQRLAADAVIVSDTGMWDEDTPTVCTGMRGLAECEIVLHGPDQDIHSGSFGGAVPNPATAVARLVAALHDEHARVAIPGFYDGVVELTDRERELFAELPFDEERWLRTAKSYATLGEAGHTTLERVWARPTAEVNGIGGGYQGPGSKTVIPSSAMVKLSFRLVAGQDPDHVEKAVRDWAAGQVPAGIRQEITFGAATRPCLTPLDHPALQSVVRAMGRAFGRPIRFTREGGSGPAADLQEVLGAPVLFLGISVPSDGWHAPNEKVELDLLLKGVETTAYLWGDLGEHFSHAP
>NZ_CP041168.1|WP_141206853.1|6072920_6073865_+|NAD(+)-diphosphatase
MTTWTDHTADRPVSLTAPSGIDRAAHHRLDEAWLAAAWSHPTTRCFVVSGGQVLIDETPDGRTELVMTPAFEAPLTEAHRYFLGIDEEGVRYFALQKDALPGRIDQSARPAGLREAGLLLSAREAGLMVHAVGLENWQRTHRFCSRCGERTVIAAAGHIRRCPACGAEHYPRTDPAVIMAVTDDQDRILLGRQVHWPEGRFSTLAGFVEPGESIEQSVRREVFEEAGITVGPVEYVASQPWPFPSSLMLGFKARAISTDINVDGDEIHEARWFSRDELQAAFESGEVLPPYGISIAARLIELWYGKPLPTRSFV
>NZ_CP041168.1|WP_020136719.1|6073956_6074199_-|mycoredoxin
MQGTVTMYSTTWCGYCQRLKKQMDREGIAYTEINIEQDPASAAFVEKANGGNQTVPTVLFGDGSTLTNPSLAQVKQKIGA
>NZ_CP041168.1|WP_141209435.1|6074463_6076602_+|AAA-family-ATPase
MLEGLDPEQREVATSLHGPVCVLAGAGTGKTRAITHRIAYGVRAGILQPSSVLAVTFTNRAAGEMRGRLRQLGAAGVQARTFHSAALRQLQYFWPKAVGGSMPRLVDRKIQLVADAAAACRIRLDRGELRDVTGEIEWSKVTQTVPSDYALAAAKAGREAPRAAAEIAQLYAAYEDVKRERAVIDFEDVLLLTVAILQDRHDIAEQVRSQYQHFVVDEYQDVSPLQQRLLELWLGQRDSLCVVGDASQTIYSFTGATPDHLLDFRTRHPGATVVKLVRDYRSTPQVVHLANGLLAQARGRAADHRLELISQRRSGPEPVYTEYTDEPAEAEGAARRIRDLMDAGVRASEIAILFRTNSQSETYEQALADAGVPYQLRGAERFFDRPEVRRAIVNLRGAARFGGNDTRLDDAVDLPSQVRAVLSGEGWTSEPPAGSGAVRERWESLAALVNLAQDFAAARPGATLNDLVAELDERAGAQHAPTVEGVTLASLHSAKGLEWDAVFLVGVAEGMMPITYARTDEQIEEERRLLYVGVTRARERLHVSWSLSRSPGGRPNRRPSRFLDGLRPGSTATAGRAAAAGPGGVERGFTSPAGEVPRRTRRTPARCRVCGRTLTDAGEMKLMRCEDCPSDMDEGLYERLRAWRAVQAERSGQPAFCVFTDKTLMAIAEAVPDDEHELTRIPGVGMRKLNRYGADVLAICAGQEVAGEEDED
>NZ_CP041168.1|WP_079069728.1|6076771_6077095_+|hypothetical-protein
MISINSTKAISTAKMTDRSVVSTCMLGVSNLGTGLSGISAVRPASSLSLAVLPVRERNERPTKALEAVVAQAHAYAFAAAGAGFRKLTTQHHQMWAFRGPEPWSDPA
>NZ_CP041168.1|WP_028809468.1|6077268_6077637_+|WhiB-family-transcriptional-regulator
MQLEAHAPSVPPSATLPPPGSTEDSTLIPLTALTALDDAIENLGVPVPCRSYDPEVFFAESPADVEYAKSLCRTCPLMEACLAGAKERREPWGVWGGELFVQGVVVARKRPRGRPRKNPVTA
>NZ_CP041168.1|WP_141206854.1|6077633_6077960_+|hypothetical-protein
MNTIAGTIDRPLTNDPKKQAPMKPSTSEPAGSAIPDFTTTGAIDSRQNRTREMQLIPEALARAHMHDRLHEAEQERRAIRLATARRMQRRAERASLRARRALAMAVMQ
>NZ_CP041168.1|WP_141206855.1|6078063_6078282_+|hypothetical-protein
MTTPSGDSDDGGFPHRDAEARPLVCARCGKRAGGPEPTWTLSVENGVRQYVCDTCSREHLRAIEGRLDSAWW
>NZ_CP041168.1|WP_141206856.1|6078288_6079659_-|AarF/ABC1/UbiB-kinase-family-protein
MSDLPRKAVTRTAKLAALPLGFAGRATWGLGKRIVGESAEIVGRELQQRTADQLFKVLGELKGGAMKFGQALSVFESALPEEVAGPYRAALTKLQEAAPPMPTRTVHTVLEERLGEDWRQLFAEFDDKPSAAASIGQVHRAVWHDGREVAVKVQYPGAGEALLSDLNQLGRFARLLGPLVPGIDIKPLINELRDRVSEELDYGLEAQAQQAHAEEFADDPDVVVPAVVHQGEQVLITEWIDGVPLSEVIADGTQEQRDRAGQLLARFLFSGSARTGLLHADPHPGNFRLLPGGPEGEEDWRLGVLDFGTVDRLPGGLPDTIGTSLRMTLEGDAEAVYDLLRTEGFVKESIELDPDAVLDYLLPIIEPAVVDEFTFTRGWMRSQAARIADPRSPAHQLGKQLNLPPAYLLIHRVTLSTIGVLCQLGAAVRLREELEEWLPGFLPEDDAGEDESAAEA
>NZ_CP041168.1|WP_141209436.1|6079651_6080869_-|TOMM-precursor-leader-peptide-binding-protein
MVPRMKPALRRGWRDLHTVQFGMTPAHAMTLGPMDRATGDFLDLLNGTRGLALLREEARGRDLPEGQVDALVDRLARAGLVEDAKGGGPAADVLRGKKEVMDRLAPDLASLSLTTSAPDDAIGLLAARRSLRVQVRGAGRVGAVLAALLSGAGVGEVDVRDWGRVEPGDVAPGGLPAASVGERRDTAARRAVSSAAPGRPPRRASRTAAGGDAPGFSLVILAPRDDVDVHAPAVAVAEPLVRSGTPHLYAGVVEATGVVGPFVLPGETGCAGCLHETRTDRDEAWPRLVAQWRSGGRPRSARPCDLALATTVAGLAAAHALAFLDGRVPSSAGARWEVSLPGLSWHARPVWPHAACPCGAAEKGKGEHTSKEEAGHETMAVQGSSEESCRKATAPRPAGTWRAHV

Crispr_ID: NZ_CP041168_9

• CRISPR_ID: NZ_CP041168_9
• CRISPR_location: 6282321-6282449
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_9

Consensus_repeat	Method
GCGGCCTCGGTGCGCAGCCGGTCGGCCTC	CRISPRCasFinder

spacers of NZ_CP041168_9

>9.1|6282350|70|NZ_CP041168|CRISPRCasFinder
CTCCTGGGCCTGCTCGTGCAGCCCGGCGACCGAGTCGCGGACCTGCTGGGCGTGCTGCTCGGCGGCCGAC

CRISPR arrays and Neighbor proteins around NZ_CP041168_9

CRISPR arrays

The CRISPR arrays of NZ_CP041168_9

>merge|NZ_CP041168|9|6282321-6282449|CRISPRCasFinder
TCGGCGGCGGAGCGCAGCCCGGTGATCTCCTCCTGGGCCTGCTCGTGCAGCCCGGCGACCGAGTCGCGGACCTGCTGGGCGTGCTGCTCGGCGGCCGACACCATCTCCGTGGCCCGCCGGTCCGCCTCC

>NZ_CP041168|9|9|6282321-6282449|CRISPRCasFinder
TCGGCGGCGGAGCGCAGCCCGGTGATCTC	CTCCTGGGCCTGCTCGTGCAGCCCGGCGACCGAGTCGCGGACCTGCTGGGCGTGCTGCTCGGCGGCCGAC
ACCATCTCCGTGGCCCGCCGGTCCGCCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141206990.1|6292134_6292611_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP041168.1|WP_062027045.1|6290005_6290674_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP041168.1|WP_141206991.1|6292703_6293501_-|AIM24-family-protein	unknown	unknown	gnl|CDD|224924
NZ_CP041168.1|WP_030320280.1|6273142_6273535_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_020136530.1|6293497_6294148_-|AIM24-family-protein	unknown	unknown	gnl|CDD|376704
NZ_CP041168.1|WP_141206981.1|6277588_6278359_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224196
NZ_CP041168.1|WP_141206979.1|6272214_6272886_-|endonuclease-NucS	unknown	unknown	gnl|CDD|235114
NZ_CP041168.1|WP_020136551.1|6269031_6269355_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP041168.1|WP_141206989.1|6290670_6292065_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP041168.1|WP_141206983.1|6279701_6280637_-|cellulose-binding-protein	unknown	unknown	gnl|CDD|274008
NZ_CP041168.1|WP_141206985.1|6285702_6286905_+|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP041168.1|WP_141206980.1|6275258_6276137_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NZ_CP041168.1|WP_141206987.1|6288021_6289245_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP041168.1|WP_062027061.1|6273649_6274678_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NZ_CP041168.1|WP_020136539.1|6285112_6285553_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NZ_CP041168.1|WP_141206978.1|6269584_6272119_+|ATP-binding-protein	unknown	unknown	gnl|CDD|374124
NZ_CP041168.1|WP_141206988.1|6289252_6289879_-|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377032
NZ_CP041168.1|WP_141206982.1|6278361_6279318_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NZ_CP041168.1|WP_141206986.1|6286939_6287896_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
NZ_CP041168.1|WP_020136546.1|6274901_6275243_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141206990.1|6292134_6292611_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.0185e-15
NZ_CP041168.1|WP_062027045.1|6290005_6290674_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.87181e-85
NZ_CP041168.1|WP_141206991.1|6292703_6293501_-|AIM24-family-protein	gnl|CDD|224924	COG2013, COG2013, Uncharacterized conserved protein [Function unknown].	1.12462e-07
NZ_CP041168.1|WP_062027061.1|6273649_6274678_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	4.61615e-56
NZ_CP041168.1|WP_020136530.1|6293497_6294148_-|AIM24-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	3.5043e-40
NZ_CP041168.1|WP_141206981.1|6277588_6278359_-|ABC-transporter-permease-subunit	gnl|CDD|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	0.00570677
NZ_CP041168.1|WP_141206979.1|6272214_6272886_-|endonuclease-NucS	gnl|CDD|235114	PRK03298, PRK03298, endonuclease NucS.	3.80759e-178
NZ_CP041168.1|WP_020136551.1|6269031_6269355_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.23396e-20
NZ_CP041168.1|WP_141206989.1|6290670_6292065_+|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.43477e-46
NZ_CP041168.1|WP_141206983.1|6279701_6280637_-|cellulose-binding-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	3.33193e-06
NZ_CP041168.1|WP_141206985.1|6285702_6286905_+|acetyl-CoA-C-acyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP041168.1|WP_141206980.1|6275258_6276137_-|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.000115273
NZ_CP041168.1|WP_141206987.1|6288021_6289245_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.10968e-23
NZ_CP041168.1|WP_141206986.1|6286939_6287896_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	1.63312e-120
NZ_CP041168.1|WP_020136539.1|6285112_6285553_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	2.12739e-52
NZ_CP041168.1|WP_141206978.1|6269584_6272119_+|ATP-binding-protein	gnl|CDD|374124	pfam15800, CiPC, Clock interacting protein circadian. CiPC is a family of proteins found in eukaryotes. The protein was identified in sheep as a gene-orthologue involved in regulation of the circadian clock. Proteins in this family are typically between 220 and 400 amino acids in length.	7.51707e-07
NZ_CP041168.1|WP_141206988.1|6289252_6289879_-|PepSY-domain-containing-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	9.82579e-08
NZ_CP041168.1|WP_141206982.1|6278361_6279318_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	3.6759e-94

Protein sequences

>NZ_CP041168.1|WP_141206983.1|6279701_6280637_-|cellulose-binding-protein
MSDTSPYGFELVRRGYDRAQVDERISKLVSDRDSALSRITALEKRIEELHLETQNAQAQVSDAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAEQHRELAESAAQQVRNDAESFAAERKSKAEDEGVRIVEKAKSDASQLRAEAQKDAQSKREEADALFEETRAKAAQAAADFETNLAKRREQSERDLASRQQKAEKRLAEIEHRAEQLRLEAEKLRTDAERRARQTVETAQRQAEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREMLATLTGAAVAAAGSPVEDEPISRGVPAQQSR
>NZ_CP041168.1|WP_141206982.1|6278361_6279318_-|ATP-binding-cassette-domain-containing-protein
MIELAGLTKRYGEKVAVNNLTFTVRPGIVTGFLGPNGAGKSTTMRMMLGLDRPTAGDVRIDGKHYDQLKDPLTYIGALLDAKAMHGGRSAYNHLLCLAQSNGIPTKRVHEVLDTVGLTAVAKKKAKGFSLGMGQRLGIAGALLGDPRILMFDEPVNGLDPEGIHWIRNLMKSLAAQGRTVFVSSHLMSEMALTADHLVVIGQGRLLADTSMADFIAQNSRSYVRIRTPQRERLLDVLHAAGVTVVETGNGTLEVDGGKSEHIGELAAQHQIVLHELSPQQASLEEAFMQLTAESVEYHAHSDAPSGPQPAWGDAWKGK
>NZ_CP041168.1|WP_141206981.1|6277588_6278359_-|ABC-transporter-permease-subunit
MAATQVIRSEWTKIRSVASTVWTLSLAVVVTVGLGILISALSKNEFDTMSRKDRLSFDPTFISFAGMSLGQLAMIVFGVLVVSNEYSTGMIRTSLAAVPQRGTFLASKIAVATGLCLVVGLVTSFVTFFLGQAMLGSHRAEIGDPGVLRAVIGGGVYMTLIAMFSMGVAAMLRSPMLSLGILMPFFFLISNILGNVSATKKVGRFLPDQAGSKIMQVVTPIDDDSPYGPWGGLGIMALWVAAALIGAYVLLKKRDA
>NZ_CP041168.1|WP_141206980.1|6275258_6276137_-|ABC-transporter-permease-subunit
MSTPQPSMPQAQPAVPTWQAAGGPAYAGYTSPIPVVRTHLGHAIASEWTKIRSVRSTMWTLGVFVLIMIGIGLGAAALIAANSSPDDLRDQNPLSFGFFGLLLGSMCVITLGVLTTASEYGTGMIRTTMVACPSRGRVLAAKSIVFFTVAFVTTLVSVLLVALADIALLDGAPEPTGQEWLKGTLGISLYIALLGLLSLIIGSIIRHSAGAITIMIGVVLAPLVIALFMFSQSLEGVRQALFEYSIPNQLSVFYANSLTDSGPSGWDPLWIILGVTAVAFAGAYALLEKRDV
>NZ_CP041168.1|WP_020136546.1|6274901_6275243_+|hypothetical-protein
MSPRRNRPKGSGSSDPADRSAEDDRSGRYGGFQSSTHWQGEDWNVRHVAGASAQGKTYRCPGCDQMIPDGVPHVVAWPDHSGVDERRHWHKACWNARDRRTTRVQRSRNAPRF
>NZ_CP041168.1|WP_062027061.1|6273649_6274678_-|LLM-class-flavin-dependent-oxidoreductase
MHVGTFLLAAQFPGQGQGEALHRAVRSAEVAEEAGLDAVWLAEHHFVPYGTCPSAITLAALLLGRTRRIRVGTAVSVLPTVHPVALGEQAALLHMTSGGRFSLGVGRGGPWVDLEVFGAGLEAYEKGFPESLDLLVRWLREPSVGADGERFRFREVPVVPRPSESLTEADGPEVIVACTSPASVRLAAERGLPMLLGMHVGDEEKAEMVALWRRQARAAGHAPQKVLEAPHVSAGVCQIADRRTDAVEALVKAMPGWLRQGLGAHVTVDGRVRQMRDPVAYTELLCGLHPVGTPRLCADRLAATSERTGISRFALLVEGSGDLAATEENVRRLGGEVLPHLT
>NZ_CP041168.1|WP_030320280.1|6273142_6273535_+|hypothetical-protein
MSLDVSPALLEKAERGEVDEAEFVDCVRTSLPYAWEMISSLVAQLKVDGGNFADNQTPPPDEQARGQLLRALASDAIRGALQRHFGVRLAFQNCHRVAVFPLDSSVDETLTRFTSVRSQLLNQSPEFRDC
>NZ_CP041168.1|WP_141206979.1|6272214_6272886_-|endonuclease-NucS
MRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCTLKEGTGDEEGVWTVVNKAGEKLIITMEEVLHDSSHELGVDPGLIKDGVEAHLQELLADRIETLGDGYTLIRREYMTAIGPVDILCRDAEGQTVAVEIKRRGEIDGVEQLTRYLDLLNRDPHLAPVRGIFAAQEIKPQARVLATDRGIGCAVLDYDALRGIEDDKLRLF
>NZ_CP041168.1|WP_141206978.1|6269584_6272119_+|ATP-binding-protein
MDPNNREPEEYGHDGDGGSPRQRPPRDSLTSDFGQHAPALARTVQLVAGDYLLTVNPVDGSEIEACPPGERPGRPAKYGAAERAEVDRAARPPVPPGPTRTTLPLLARQDEREQLVRMLARGRSVRLTGPAGSGRTSLLDVVAEDCSDLAPDGVVRLTGFRRTAAELLYDLYYAVFDSPLHRPDRDELLSCVREIGAVVVLDDIEFGGAALDELLDATPECAFVIGATPEVPAPSADSAVEEVVLSGLERADGVELLERAVGRVLTEEESNWAGDLWFESEGLPLRFVQAGALLRQRDRQRAGAGAVDEFGVFAEMAVADVPPPTDDADEIPLPALGDAAAPAPLLASRLSESARATLRFAVALGGEVPHQAHLPALVGDTHADAALGELADAGLVSPVGSRYRLAAGVLAQLEAAGYADDIEDRARTAAQHYAWWAGHPSVTPERVCAEADALLAALDVLVPVTVAPLDGEEETIAVRLARTAAPAFAAGGHWGAWERSLWAGSEASRLAGVVSERAYFHHELGILALCGGELDRARAELEASIGLRGALADKRGTVAGRRALALVSDRDGTTPATGLLGLGATAGEEVPDARHDESASPPGGVPAAFPRLQPPGESQTVVVHRTPAVGPSRKARGGLKGLAKRNLVAAGAGALLVAVLGTVVTLGATSDNDPNSPSNEVGVNPSASVGIDDGNLGADVPSNDDKGDTGTATSRPTDPGPDGTYGTSDDPTPTGGTTPSAKPSGTRGSGSSPTSRPTTPRPSNSPSAPSSPTGRPTGSGSASATPSGPTGTPTESPSSTPSGTTPTNSTTASGPASSAPVETSSSASAPASSAVSGTPSGQVI
>NZ_CP041168.1|WP_020136551.1|6269031_6269355_+|STAS-domain-containing-protein
MYIRGDHAELVVGGRLDVRSAADARTVLHSAVDDGAGDLVLDLSELDSWDATGLGVIMGAHRRAGRCGRRLVLRDVPPQMQRLLVATRLHRILAIEGGIGVESLPRV
>NZ_CP041168.1|WP_020136539.1|6285112_6285553_-|methylmalonyl-CoA-epimerase
MLTRIDHIGIACFDLDKTVEFYRATYGFEVFHSEVNEEQGVREAMLKINETSDGGASYLQLLEPTRPDSTVAKWLDKNGEGVHHIAFGTADVDAEAADIKDKGVRVLYEEPRRGSMGSRITFLHPKDCHGVLTELVTSAPVESPEH
>NZ_CP041168.1|WP_141206985.1|6285702_6286905_+|acetyl-CoA-C-acyltransferase
MSGSNSTTSVIVAGARTPMGRLLGSLKSFSGADLGGFAIKAALDRAGIGGDQVQYVIMGQVLQAGAGQIPARQAAVKAGIPMNVPALTINKVCLSGLDAIALADQLIRAGEFDVIVAGGQESMTNAPHLLPKSREGFKYGAIEMLDAMAYDGLTDAFENIAMGESTEKHNTRLGILRPEQDEFSALSHQRAAAAQKNGIFEAEITPVEIPQRKGEPVVFSKDEGIRGDTTAESLGKLRPAFTKDGTITAGSASQISDGAAAVVVMSKAKAQELGLDWIAEIGAHGNVAGPDNSLQSQPSNAILHALKKEGLEVSDLDLIEINEAFAAVAVQSMKDLGVSTEKVNVNGGAIALGHPIGMSGARLVLHLALELKRRGGGVGAAALCGGGGQGDALVVRVPKA
>NZ_CP041168.1|WP_141206986.1|6286939_6287896_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MQDVSSLVALAREGRPRAVARLISLVEGASPQLREVMQTLAPLTGNAYVVGLTGSPGVGKSTSTSALVTAYRKQDRRVGVLAVDPSSPFSGGALLGDRVRMSEHASDPGVYIRSMATRGHLGGLAWSAPQAIRVLDAAGCDVILVETVGVGQSEVEIASQADTSVVLLAPGMGDGIQAAKAGILEIGDVYVVNKADRDGADATARELNHMLGLGESRKPGDWRPPIVKTVASRAEGVDEVVEALEKHRAWMEEHGVLAERRRARAAHEVEAIALTALRERIGDLRGDRRLGALAERIVAGELDPYRAADELVNGLTQG
>NZ_CP041168.1|WP_141206987.1|6288021_6289245_+|MFS-transporter
MSASYRRVLRLPHARRTFAAALLGRLSYGVVPLSVMLSVLRASDSYAVAGAVMALFGATVVLLAPARAALVDRYGPRRALVTLPAAHLALLGMLTAAVWRPGAPPVLLGALAALAGACAPPLGPTMRAVWSRLAQDDKALLQRAYSLDGVAEELLFVSGPLLVGGLVAVAPPTAGIVVGAALLLAGTAGFVRSPAVRAVPAAGPVSVRRDRGGPRILRRLGRPVAAAASVGLAIGVLDLLVVVFAERHGHGGASVAWVLAALSAGSAVGGMLNGAVNWRAPAHARLAALTLCLGLALLGAGCAPGLGTLALFVSGAGFFVSPALTTAYLIADEAVPPEARTRAGAWVNTAVNAGSTGGTALAGALAGRLPVAVCFAVTGGVVVLAAALVMGQGARVGGALREEAAVR
>NZ_CP041168.1|WP_141206988.1|6289252_6289879_-|PepSY-domain-containing-protein
MKRNIVIATLTAAALAAGGTVAAFAAGDDEATATQRQAGTDARAAADRDDESAGDDSVDDDRTAAPRGSVTAADAIAAALKHTPGTALAADFEDDGAGTWEVTVVRGDGSEYDVRIAPGSGKVLGAQRDADDDHDRDDRAELAAVKGASTDAREAALAAAAKGTVTEVGLEEDNGAVAWSAETVKDGTHGEWRVALDSGRVTQDREED
>NZ_CP041168.1|WP_062027045.1|6290005_6290674_+|response-regulator-transcription-factor
MRLLIVEDEKRLAVSLAKGLTAEGYAVDVVHDGREGLHRATEGSYDLVILDIMLPGLNGYRVCAALRAAGHEVPILMLTAKDGEYDEAEGLDTGADDYLTKPFSYVVLVARIKALLRRRGNGSGASPVLELGGLRIDTAARRVLLDGTEVTLTAKEFSVLEQLAVRAGEVVSKAQILEHVWDFAYDGDPNIVEVYVSTLRRKLDAGLIRTVRGAGYRLEAGR
>NZ_CP041168.1|WP_141206989.1|6290670_6292065_+|HAMP-domain-containing-protein
MRRLFGSVRARATLGATLVVAVALVAAGASVLLSLRSDLIDRAGTQAERTARNVAAHLAAGTAYDDLKLDDEEEPVQVVDAHGTLVAASEHLERISGTGTGEVRPAPQQDTGSGDEDDDSALEPGEIADEVAFTDGSATIDGESADYRFAALEVDVQDKGRLTVYAGASLDAEQGAVDTAQTVMLIGFPLLLGVVAAVTWLVTRRALRPVEGIRTEMAAITASEDLARRVPVPDTHDEVARLARTTNETLAALETSVERQRRFVADASHELRSPIASLRTQLEVAAAHPELLDVDGAVEDTVRLQRLAADLLLLARLDAGERRGDARVDLGELAARCARGRDGVTVEAPAVEVTGSRGQLERVLGNLLDNAQRHARAAVAVTVRRDGEWAVVSVADDGSGVPAADRERVFERFVRLDEARARDDGGAGLGLAIARDVAVRHGGTLTVRDAPAGGALFELRLPVG
>NZ_CP041168.1|WP_141206990.1|6292134_6292611_-|MarR-family-transcriptional-regulator
METETATRWLTDAEQCAWRTHLEVNRLLTYQLERDLQPFGLTMNDYEILVNLSESEGVRMRMSDLASATLQSKSRLSHQITRMENADLVRRENCESDRRGLYAVLTEHGMETMKKVAPHHVASVRRHFIDLQTDESLAELSKALKPVAEHLRGHQGRP
>NZ_CP041168.1|WP_141206991.1|6292703_6293501_-|AIM24-family-protein
MSHYPGTGPTVYDPMTLPSDDNVNNYTFCVELKGSQWFLQKGKMIAYYGQMDFNGIGHGRLDGLVRTSFHSPLHASDWVVAQGSGKMLLADRAFDVNSYDLEDGNLTIRSGNLLAFQPSLALKQSIVPGFLTLIGTGKFVAASNGPVVFMEPPIRVDPQALVGWADCPSPCHHYDHGYMTGVMGGLRAMTGLGGASGEEHQFEFVGAGTVLLQSTEVLMAEQATGVVPNEPGVPGGYGAPAGHPQQPGVPRLPGQLGDLQRRFGL
>NZ_CP041168.1|WP_020136530.1|6293497_6294148_-|AIM24-family-protein
MPFREINSKMVEATVMPGQRLFSQRGAMLAYKGEVSFTPNIQGGQGGIMSMIGRRVANEDTPLMTVEGSGTVLFGHGGHHVTVINLTGDTLYVEADRLLAFEGTLQQGTMFMGSQGGVMGMVRGQISGQGLFTTTLKGHGSVAVMAHGGVFEVPITPQRPVHVDPQAYVAHHGDVRNKLSTALGWRDMVGRGSGEAFQLELSGHGAVYVQASEEKL

Crispr_ID: NZ_CP041168_10

• CRISPR_ID: NZ_CP041168_10
• CRISPR_location: 6282582-6282895
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP041168_10

Consensus_repeat	Method
GCGGCCTCGGTGCGCAGCCGGTCGGCCTC	CRISPRCasFinder

spacers of NZ_CP041168_10

>10.1|6282611|25|NZ_CP041168|CRISPRCasFinder
CTCCTGGGCGGCGGCCAGCGTCTCG
>10.2|6282665|37|NZ_CP041168|CRISPRCasFinder
GGCCTGCGCCTCCGCCCGGACCCGGTTCGCGGTGTCC
>10.3|6282731|70|NZ_CP041168|CRISPRCasFinder
CGCGGCGGCCTCGGAGCGCAGCCGTACGGCGACGGCCTCGCCCTCGGCACGGGAGGCGGACGCGTCGGCC
>10.4|6282830|37|NZ_CP041168|CRISPRCasFinder
GGCCTCGGCCTGCTGCTGGAGGGTGCGGATCCGCTCG

CRISPR arrays and Neighbor proteins around NZ_CP041168_10

CRISPR arrays

The CRISPR arrays of NZ_CP041168_10

>merge|NZ_CP041168|10|6282582-6282895|CRISPRCasFinder
TCGGCCTCGCGGCGGCGCCGGTTGGCCTCCTCCTGGGCGGCGGCCAGCGTCTCGGACGCCTCGGTGGCGAGCCGCTCGGCGGCGGCCTGCGCCTCCGCCCGGACCCGGTTCGCGGTGTCCTGCGCCTCGGACTTCAGCCGCTCCGCCTCCGCGGCGGCCTCGGAGCGCAGCCGTACGGCGACGGCCTCGCCCTCGGCACGGGAGGCGGACGCGTCGGCCGCGGCCTCGGTGCGCAGCCGGTCGGCCTCGGCCTCGGCCTGCTGCTGGAGGGTGCGGATCCGCTCGGCGGCCTCGCTGCGCAGCCGGTCGGCCTC

>NZ_CP041168|10|10|6282582-6282895|CRISPRCasFinder
TCGGCCTCGCGGCGGCGCCGGTTGGCCTC	CTCCTGGGCGGCGGCCAGCGTCTCG
GACGCCTCGGTGGCGAGCCGCTCGGCGGC	GGCCTGCGCCTCCGCCCGGACCCGGTTCGCGGTGTCC
TGCGCCTCGGACTTCAGCCGCTCCGCCTC	CGCGGCGGCCTCGGAGCGCAGCCGTACGGCGACGGCCTCGCCCTCGGCACGGGAGGCGGACGCGTCGGCC
GCGGCCTCGGTGCGCAGCCGGTCGGCCTC	GGCCTCGGCCTGCTGCTGGAGGGTGCGGATCCGCTCG
GCGGCCTCGCTGCGCAGCCGGTCGGCCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141206990.1|6292134_6292611_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP041168.1|WP_062027045.1|6290005_6290674_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP041168.1|WP_141206991.1|6292703_6293501_-|AIM24-family-protein	unknown	unknown	gnl|CDD|224924
NZ_CP041168.1|WP_030320280.1|6273142_6273535_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_020136530.1|6293497_6294148_-|AIM24-family-protein	unknown	unknown	gnl|CDD|376704
NZ_CP041168.1|WP_141206981.1|6277588_6278359_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224196
NZ_CP041168.1|WP_141206979.1|6272214_6272886_-|endonuclease-NucS	unknown	unknown	gnl|CDD|235114
NZ_CP041168.1|WP_020136551.1|6269031_6269355_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP041168.1|WP_141206989.1|6290670_6292065_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP041168.1|WP_141206983.1|6279701_6280637_-|cellulose-binding-protein	unknown	unknown	gnl|CDD|274008
NZ_CP041168.1|WP_141206985.1|6285702_6286905_+|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP041168.1|WP_141206980.1|6275258_6276137_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NZ_CP041168.1|WP_141206987.1|6288021_6289245_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP041168.1|WP_062027061.1|6273649_6274678_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NZ_CP041168.1|WP_020136539.1|6285112_6285553_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NZ_CP041168.1|WP_141206978.1|6269584_6272119_+|ATP-binding-protein	unknown	unknown	gnl|CDD|374124
NZ_CP041168.1|WP_141206988.1|6289252_6289879_-|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377032
NZ_CP041168.1|WP_141206982.1|6278361_6279318_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NZ_CP041168.1|WP_141206986.1|6286939_6287896_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|224617
NZ_CP041168.1|WP_020136546.1|6274901_6275243_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141206990.1|6292134_6292611_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.0185e-15
NZ_CP041168.1|WP_062027045.1|6290005_6290674_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.87181e-85
NZ_CP041168.1|WP_141206991.1|6292703_6293501_-|AIM24-family-protein	gnl|CDD|224924	COG2013, COG2013, Uncharacterized conserved protein [Function unknown].	1.12462e-07
NZ_CP041168.1|WP_062027061.1|6273649_6274678_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	4.61615e-56
NZ_CP041168.1|WP_020136530.1|6293497_6294148_-|AIM24-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	3.5043e-40
NZ_CP041168.1|WP_141206981.1|6277588_6278359_-|ABC-transporter-permease-subunit	gnl|CDD|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	0.00570677
NZ_CP041168.1|WP_141206979.1|6272214_6272886_-|endonuclease-NucS	gnl|CDD|235114	PRK03298, PRK03298, endonuclease NucS.	3.80759e-178
NZ_CP041168.1|WP_020136551.1|6269031_6269355_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.23396e-20
NZ_CP041168.1|WP_141206989.1|6290670_6292065_+|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.43477e-46
NZ_CP041168.1|WP_141206983.1|6279701_6280637_-|cellulose-binding-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	3.33193e-06
NZ_CP041168.1|WP_141206985.1|6285702_6286905_+|acetyl-CoA-C-acyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP041168.1|WP_141206980.1|6275258_6276137_-|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.000115273
NZ_CP041168.1|WP_141206987.1|6288021_6289245_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.10968e-23
NZ_CP041168.1|WP_141206986.1|6286939_6287896_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	1.63312e-120
NZ_CP041168.1|WP_020136539.1|6285112_6285553_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	2.12739e-52
NZ_CP041168.1|WP_141206978.1|6269584_6272119_+|ATP-binding-protein	gnl|CDD|374124	pfam15800, CiPC, Clock interacting protein circadian. CiPC is a family of proteins found in eukaryotes. The protein was identified in sheep as a gene-orthologue involved in regulation of the circadian clock. Proteins in this family are typically between 220 and 400 amino acids in length.	7.51707e-07
NZ_CP041168.1|WP_141206988.1|6289252_6289879_-|PepSY-domain-containing-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	9.82579e-08
NZ_CP041168.1|WP_141206982.1|6278361_6279318_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	3.6759e-94

Protein sequences

>NZ_CP041168.1|WP_141206983.1|6279701_6280637_-|cellulose-binding-protein
MSDTSPYGFELVRRGYDRAQVDERISKLVSDRDSALSRITALEKRIEELHLETQNAQAQVSDAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAEQHRELAESAAQQVRNDAESFAAERKSKAEDEGVRIVEKAKSDASQLRAEAQKDAQSKREEADALFEETRAKAAQAAADFETNLAKRREQSERDLASRQQKAEKRLAEIEHRAEQLRLEAEKLRTDAERRARQTVETAQRQAEDIVADANAKADRIRSESERELAALTNRRDSINAQLTNVREMLATLTGAAVAAAGSPVEDEPISRGVPAQQSR
>NZ_CP041168.1|WP_141206982.1|6278361_6279318_-|ATP-binding-cassette-domain-containing-protein
MIELAGLTKRYGEKVAVNNLTFTVRPGIVTGFLGPNGAGKSTTMRMMLGLDRPTAGDVRIDGKHYDQLKDPLTYIGALLDAKAMHGGRSAYNHLLCLAQSNGIPTKRVHEVLDTVGLTAVAKKKAKGFSLGMGQRLGIAGALLGDPRILMFDEPVNGLDPEGIHWIRNLMKSLAAQGRTVFVSSHLMSEMALTADHLVVIGQGRLLADTSMADFIAQNSRSYVRIRTPQRERLLDVLHAAGVTVVETGNGTLEVDGGKSEHIGELAAQHQIVLHELSPQQASLEEAFMQLTAESVEYHAHSDAPSGPQPAWGDAWKGK
>NZ_CP041168.1|WP_141206981.1|6277588_6278359_-|ABC-transporter-permease-subunit
MAATQVIRSEWTKIRSVASTVWTLSLAVVVTVGLGILISALSKNEFDTMSRKDRLSFDPTFISFAGMSLGQLAMIVFGVLVVSNEYSTGMIRTSLAAVPQRGTFLASKIAVATGLCLVVGLVTSFVTFFLGQAMLGSHRAEIGDPGVLRAVIGGGVYMTLIAMFSMGVAAMLRSPMLSLGILMPFFFLISNILGNVSATKKVGRFLPDQAGSKIMQVVTPIDDDSPYGPWGGLGIMALWVAAALIGAYVLLKKRDA
>NZ_CP041168.1|WP_141206980.1|6275258_6276137_-|ABC-transporter-permease-subunit
MSTPQPSMPQAQPAVPTWQAAGGPAYAGYTSPIPVVRTHLGHAIASEWTKIRSVRSTMWTLGVFVLIMIGIGLGAAALIAANSSPDDLRDQNPLSFGFFGLLLGSMCVITLGVLTTASEYGTGMIRTTMVACPSRGRVLAAKSIVFFTVAFVTTLVSVLLVALADIALLDGAPEPTGQEWLKGTLGISLYIALLGLLSLIIGSIIRHSAGAITIMIGVVLAPLVIALFMFSQSLEGVRQALFEYSIPNQLSVFYANSLTDSGPSGWDPLWIILGVTAVAFAGAYALLEKRDV
>NZ_CP041168.1|WP_020136546.1|6274901_6275243_+|hypothetical-protein
MSPRRNRPKGSGSSDPADRSAEDDRSGRYGGFQSSTHWQGEDWNVRHVAGASAQGKTYRCPGCDQMIPDGVPHVVAWPDHSGVDERRHWHKACWNARDRRTTRVQRSRNAPRF
>NZ_CP041168.1|WP_062027061.1|6273649_6274678_-|LLM-class-flavin-dependent-oxidoreductase
MHVGTFLLAAQFPGQGQGEALHRAVRSAEVAEEAGLDAVWLAEHHFVPYGTCPSAITLAALLLGRTRRIRVGTAVSVLPTVHPVALGEQAALLHMTSGGRFSLGVGRGGPWVDLEVFGAGLEAYEKGFPESLDLLVRWLREPSVGADGERFRFREVPVVPRPSESLTEADGPEVIVACTSPASVRLAAERGLPMLLGMHVGDEEKAEMVALWRRQARAAGHAPQKVLEAPHVSAGVCQIADRRTDAVEALVKAMPGWLRQGLGAHVTVDGRVRQMRDPVAYTELLCGLHPVGTPRLCADRLAATSERTGISRFALLVEGSGDLAATEENVRRLGGEVLPHLT
>NZ_CP041168.1|WP_030320280.1|6273142_6273535_+|hypothetical-protein
MSLDVSPALLEKAERGEVDEAEFVDCVRTSLPYAWEMISSLVAQLKVDGGNFADNQTPPPDEQARGQLLRALASDAIRGALQRHFGVRLAFQNCHRVAVFPLDSSVDETLTRFTSVRSQLLNQSPEFRDC
>NZ_CP041168.1|WP_141206979.1|6272214_6272886_-|endonuclease-NucS
MRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCTLKEGTGDEEGVWTVVNKAGEKLIITMEEVLHDSSHELGVDPGLIKDGVEAHLQELLADRIETLGDGYTLIRREYMTAIGPVDILCRDAEGQTVAVEIKRRGEIDGVEQLTRYLDLLNRDPHLAPVRGIFAAQEIKPQARVLATDRGIGCAVLDYDALRGIEDDKLRLF
>NZ_CP041168.1|WP_141206978.1|6269584_6272119_+|ATP-binding-protein
MDPNNREPEEYGHDGDGGSPRQRPPRDSLTSDFGQHAPALARTVQLVAGDYLLTVNPVDGSEIEACPPGERPGRPAKYGAAERAEVDRAARPPVPPGPTRTTLPLLARQDEREQLVRMLARGRSVRLTGPAGSGRTSLLDVVAEDCSDLAPDGVVRLTGFRRTAAELLYDLYYAVFDSPLHRPDRDELLSCVREIGAVVVLDDIEFGGAALDELLDATPECAFVIGATPEVPAPSADSAVEEVVLSGLERADGVELLERAVGRVLTEEESNWAGDLWFESEGLPLRFVQAGALLRQRDRQRAGAGAVDEFGVFAEMAVADVPPPTDDADEIPLPALGDAAAPAPLLASRLSESARATLRFAVALGGEVPHQAHLPALVGDTHADAALGELADAGLVSPVGSRYRLAAGVLAQLEAAGYADDIEDRARTAAQHYAWWAGHPSVTPERVCAEADALLAALDVLVPVTVAPLDGEEETIAVRLARTAAPAFAAGGHWGAWERSLWAGSEASRLAGVVSERAYFHHELGILALCGGELDRARAELEASIGLRGALADKRGTVAGRRALALVSDRDGTTPATGLLGLGATAGEEVPDARHDESASPPGGVPAAFPRLQPPGESQTVVVHRTPAVGPSRKARGGLKGLAKRNLVAAGAGALLVAVLGTVVTLGATSDNDPNSPSNEVGVNPSASVGIDDGNLGADVPSNDDKGDTGTATSRPTDPGPDGTYGTSDDPTPTGGTTPSAKPSGTRGSGSSPTSRPTTPRPSNSPSAPSSPTGRPTGSGSASATPSGPTGTPTESPSSTPSGTTPTNSTTASGPASSAPVETSSSASAPASSAVSGTPSGQVI
>NZ_CP041168.1|WP_020136551.1|6269031_6269355_+|STAS-domain-containing-protein
MYIRGDHAELVVGGRLDVRSAADARTVLHSAVDDGAGDLVLDLSELDSWDATGLGVIMGAHRRAGRCGRRLVLRDVPPQMQRLLVATRLHRILAIEGGIGVESLPRV
>NZ_CP041168.1|WP_020136539.1|6285112_6285553_-|methylmalonyl-CoA-epimerase
MLTRIDHIGIACFDLDKTVEFYRATYGFEVFHSEVNEEQGVREAMLKINETSDGGASYLQLLEPTRPDSTVAKWLDKNGEGVHHIAFGTADVDAEAADIKDKGVRVLYEEPRRGSMGSRITFLHPKDCHGVLTELVTSAPVESPEH
>NZ_CP041168.1|WP_141206985.1|6285702_6286905_+|acetyl-CoA-C-acyltransferase
MSGSNSTTSVIVAGARTPMGRLLGSLKSFSGADLGGFAIKAALDRAGIGGDQVQYVIMGQVLQAGAGQIPARQAAVKAGIPMNVPALTINKVCLSGLDAIALADQLIRAGEFDVIVAGGQESMTNAPHLLPKSREGFKYGAIEMLDAMAYDGLTDAFENIAMGESTEKHNTRLGILRPEQDEFSALSHQRAAAAQKNGIFEAEITPVEIPQRKGEPVVFSKDEGIRGDTTAESLGKLRPAFTKDGTITAGSASQISDGAAAVVVMSKAKAQELGLDWIAEIGAHGNVAGPDNSLQSQPSNAILHALKKEGLEVSDLDLIEINEAFAAVAVQSMKDLGVSTEKVNVNGGAIALGHPIGMSGARLVLHLALELKRRGGGVGAAALCGGGGQGDALVVRVPKA
>NZ_CP041168.1|WP_141206986.1|6286939_6287896_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MQDVSSLVALAREGRPRAVARLISLVEGASPQLREVMQTLAPLTGNAYVVGLTGSPGVGKSTSTSALVTAYRKQDRRVGVLAVDPSSPFSGGALLGDRVRMSEHASDPGVYIRSMATRGHLGGLAWSAPQAIRVLDAAGCDVILVETVGVGQSEVEIASQADTSVVLLAPGMGDGIQAAKAGILEIGDVYVVNKADRDGADATARELNHMLGLGESRKPGDWRPPIVKTVASRAEGVDEVVEALEKHRAWMEEHGVLAERRRARAAHEVEAIALTALRERIGDLRGDRRLGALAERIVAGELDPYRAADELVNGLTQG
>NZ_CP041168.1|WP_141206987.1|6288021_6289245_+|MFS-transporter
MSASYRRVLRLPHARRTFAAALLGRLSYGVVPLSVMLSVLRASDSYAVAGAVMALFGATVVLLAPARAALVDRYGPRRALVTLPAAHLALLGMLTAAVWRPGAPPVLLGALAALAGACAPPLGPTMRAVWSRLAQDDKALLQRAYSLDGVAEELLFVSGPLLVGGLVAVAPPTAGIVVGAALLLAGTAGFVRSPAVRAVPAAGPVSVRRDRGGPRILRRLGRPVAAAASVGLAIGVLDLLVVVFAERHGHGGASVAWVLAALSAGSAVGGMLNGAVNWRAPAHARLAALTLCLGLALLGAGCAPGLGTLALFVSGAGFFVSPALTTAYLIADEAVPPEARTRAGAWVNTAVNAGSTGGTALAGALAGRLPVAVCFAVTGGVVVLAAALVMGQGARVGGALREEAAVR
>NZ_CP041168.1|WP_141206988.1|6289252_6289879_-|PepSY-domain-containing-protein
MKRNIVIATLTAAALAAGGTVAAFAAGDDEATATQRQAGTDARAAADRDDESAGDDSVDDDRTAAPRGSVTAADAIAAALKHTPGTALAADFEDDGAGTWEVTVVRGDGSEYDVRIAPGSGKVLGAQRDADDDHDRDDRAELAAVKGASTDAREAALAAAAKGTVTEVGLEEDNGAVAWSAETVKDGTHGEWRVALDSGRVTQDREED
>NZ_CP041168.1|WP_062027045.1|6290005_6290674_+|response-regulator-transcription-factor
MRLLIVEDEKRLAVSLAKGLTAEGYAVDVVHDGREGLHRATEGSYDLVILDIMLPGLNGYRVCAALRAAGHEVPILMLTAKDGEYDEAEGLDTGADDYLTKPFSYVVLVARIKALLRRRGNGSGASPVLELGGLRIDTAARRVLLDGTEVTLTAKEFSVLEQLAVRAGEVVSKAQILEHVWDFAYDGDPNIVEVYVSTLRRKLDAGLIRTVRGAGYRLEAGR
>NZ_CP041168.1|WP_141206989.1|6290670_6292065_+|HAMP-domain-containing-protein
MRRLFGSVRARATLGATLVVAVALVAAGASVLLSLRSDLIDRAGTQAERTARNVAAHLAAGTAYDDLKLDDEEEPVQVVDAHGTLVAASEHLERISGTGTGEVRPAPQQDTGSGDEDDDSALEPGEIADEVAFTDGSATIDGESADYRFAALEVDVQDKGRLTVYAGASLDAEQGAVDTAQTVMLIGFPLLLGVVAAVTWLVTRRALRPVEGIRTEMAAITASEDLARRVPVPDTHDEVARLARTTNETLAALETSVERQRRFVADASHELRSPIASLRTQLEVAAAHPELLDVDGAVEDTVRLQRLAADLLLLARLDAGERRGDARVDLGELAARCARGRDGVTVEAPAVEVTGSRGQLERVLGNLLDNAQRHARAAVAVTVRRDGEWAVVSVADDGSGVPAADRERVFERFVRLDEARARDDGGAGLGLAIARDVAVRHGGTLTVRDAPAGGALFELRLPVG
>NZ_CP041168.1|WP_141206990.1|6292134_6292611_-|MarR-family-transcriptional-regulator
METETATRWLTDAEQCAWRTHLEVNRLLTYQLERDLQPFGLTMNDYEILVNLSESEGVRMRMSDLASATLQSKSRLSHQITRMENADLVRRENCESDRRGLYAVLTEHGMETMKKVAPHHVASVRRHFIDLQTDESLAELSKALKPVAEHLRGHQGRP
>NZ_CP041168.1|WP_141206991.1|6292703_6293501_-|AIM24-family-protein
MSHYPGTGPTVYDPMTLPSDDNVNNYTFCVELKGSQWFLQKGKMIAYYGQMDFNGIGHGRLDGLVRTSFHSPLHASDWVVAQGSGKMLLADRAFDVNSYDLEDGNLTIRSGNLLAFQPSLALKQSIVPGFLTLIGTGKFVAASNGPVVFMEPPIRVDPQALVGWADCPSPCHHYDHGYMTGVMGGLRAMTGLGGASGEEHQFEFVGAGTVLLQSTEVLMAEQATGVVPNEPGVPGGYGAPAGHPQQPGVPRLPGQLGDLQRRFGL
>NZ_CP041168.1|WP_020136530.1|6293497_6294148_-|AIM24-family-protein
MPFREINSKMVEATVMPGQRLFSQRGAMLAYKGEVSFTPNIQGGQGGIMSMIGRRVANEDTPLMTVEGSGTVLFGHGGHHVTVINLTGDTLYVEADRLLAFEGTLQQGTMFMGSQGGVMGMVRGQISGQGLFTTTLKGHGSVAVMAHGGVFEVPITPQRPVHVDPQAYVAHHGDVRNKLSTALGWRDMVGRGSGEAFQLELSGHGAVYVQASEEKL

Crispr_ID: NZ_CP041168_11

• CRISPR_ID: NZ_CP041168_11
• CRISPR_location: 6492725-6492789
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_11

Consensus_repeat	Method
GCACCGGGCCGCGGGAACTGACC	CRISPRCasFinder

spacers of NZ_CP041168_11

>11.1|6492748|19|NZ_CP041168|CRISPRCasFinder
CGTGCCCTGCGCGCCGTTG

CRISPR arrays and Neighbor proteins around NZ_CP041168_11

CRISPR arrays

The CRISPR arrays of NZ_CP041168_11

>merge|NZ_CP041168|11|6492725-6492789|CRISPRCasFinder
GCACCGGGCCGCGGGAACTGACCCGTGCCCTGCGCGCCGTTGGCGCCGGGCCGCGGGAGGTCGTT

>NZ_CP041168|11|11|6492725-6492789|CRISPRCasFinder
GCACCGGGCCGCGGGAACTGACC	CGTGCCCTGCGCGCCGTTG
GCGCCGGGCCGCGGGAGGTCGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141207124.1|6500642_6501305_+|DUF4241-domain-containing-protein	unknown	unknown	gnl|CDD|379427
NZ_CP041168.1|WP_141207118.1|6483009_6484605_+|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|130187
NZ_CP041168.1|WP_141207121.1|6497576_6498017_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141209460.1|6496606_6497476_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141207127.1|6505297_6505891_+|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|179314
NZ_CP041168.1|WP_030315920.1|6485575_6486148_-|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NZ_CP041168.1|WP_004983065.1|6486244_6486658_-|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|367422
NZ_CP041168.1|WP_007384912.1|6490394_6490970_-|ATP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP041168.1|WP_003993189.1|6491460_6491874_-|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|367422
NZ_CP041168.1|WP_020138705.1|6496323_6496509_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_062026781.1|6484662_6484854_+|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl|CDD|379386
NZ_CP041168.1|WP_141207123.1|6499039_6500524_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|234953
NZ_CP041168.1|WP_141207125.1|6501355_6502087_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|223943
NZ_CP041168.1|WP_003973454.1|6490950_6491349_-|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NZ_CP041168.1|WP_141207122.1|6498270_6499056_+|DUF2437-domain-containing-protein	unknown	unknown	gnl|CDD|223257
NZ_CP041168.1|WP_026248371.1|6485013_6485595_-|ATP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP041168.1|WP_141207117.1|6480512_6482858_+|polysaccharide-lyase-8-family-protein	unknown	unknown	gnl|CDD|238517
NZ_CP041168.1|WP_007384919.1|6502960_6503677_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP041168.1|WP_141207119.1|6486668_6489992_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|377989
NZ_CP041168.1|WP_141207126.1|6503867_6505292_+|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl|CDD|235490

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141207124.1|6500642_6501305_+|DUF4241-domain-containing-protein	gnl|CDD|379427	pfam14025, DUF4241, Protein of unknown function (DUF4241). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 205 and 315 amino acids in length. There is a conserved GDG sequence motif at the C-terminus.	5.97973e-57
NZ_CP041168.1|WP_141207118.1|6483009_6484605_+|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|130187	TIGR01117, methylmalonyl-CoA_decarboxylase_alpha-subunit, methylmalonyl-CoA decarboxylase alpha subunit. This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds].	0
NZ_CP041168.1|WP_141207125.1|6501355_6502087_+|HAD-IA-family-hydrolase	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	8.26887e-34
NZ_CP041168.1|WP_141207127.1|6505297_6505891_+|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	6.74993e-126
NZ_CP041168.1|WP_030315920.1|6485575_6486148_-|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	4.97233e-46
NZ_CP041168.1|WP_007384912.1|6490394_6490970_-|ATP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	3.07001e-46
NZ_CP041168.1|WP_003993189.1|6491460_6491874_-|roadblock/LC7-domain-containing-protein	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	5.94463e-23
NZ_CP041168.1|WP_004983065.1|6486244_6486658_-|roadblock/LC7-domain-containing-protein	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	1.51599e-22
NZ_CP041168.1|WP_062026781.1|6484662_6484854_+|acyl-CoA-carboxylase-subunit-epsilon	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	6.10402e-09
NZ_CP041168.1|WP_141207123.1|6499039_6500524_+|glutamate--tRNA-ligase	gnl|CDD|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP041168.1|WP_003973454.1|6490950_6491349_-|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	2.04492e-38
NZ_CP041168.1|WP_141207122.1|6498270_6499056_+|DUF2437-domain-containing-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	8.57098e-102
NZ_CP041168.1|WP_026248371.1|6485013_6485595_-|ATP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	2.02103e-45
NZ_CP041168.1|WP_141207117.1|6480512_6482858_+|polysaccharide-lyase-8-family-protein	gnl|CDD|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
NZ_CP041168.1|WP_007384919.1|6502960_6503677_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.45656e-45
NZ_CP041168.1|WP_141207119.1|6486668_6489992_-|HAMP-domain-containing-protein	gnl|CDD|377989	pfam08376, NIT, Nitrate and nitrite sensing. The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.	8.6011e-23
NZ_CP041168.1|WP_141207126.1|6503867_6505292_+|3-isopropylmalate-dehydratase-large-subunit	gnl|CDD|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0

Protein sequences

>NZ_CP041168.1|WP_003993189.1|6491460_6491874_-|roadblock/LC7-domain-containing-protein
MSQAAQNLNWLITNFVDNTPGVSHTVVVSADGLLLAMSEGFPRDRADQLAAVASGLTSLTAGASRIFEGGSVAQTVVEMERGFLFLMSVSDGSSLAVLAHPECDIGLVGYEMALLVDRAGAVLTPDLRAELQGSLLH
>NZ_CP041168.1|WP_003973454.1|6490950_6491349_-|DUF742-domain-containing-protein
MTPPTASHDPYAEPYEDEGDQPLVRPYAMTGGRTRPRYQLAIEALISTTADPAALMGLLPEHQRICHLCREVKSVAEVSALLAMPLGVARILVADLAEAGLVAIHQPGGDENNGGAPDVTLLERVLSGLRKL
>NZ_CP041168.1|WP_007384912.1|6490394_6490970_-|ATP-binding-protein
MDFASSDAGRATTSAKIVVAGGFGVGKTTFVGAVSEINPLRTEAVMTSASAGIDDLTHTGDKTTTTVAMDFGRITLDQDLILYLFGTPGQDRFWFMWDDLVRGAIGAVVLVDTRRLADCFPAVDYFENSGLPFVVALNGFDGHQPYAPEEVREALQIGPDAPIITTDARHRSDAKSALITLVEHALMARLR
>NZ_CP041168.1|WP_141207119.1|6486668_6489992_-|HAMP-domain-containing-protein
MRRSKNGPEPSARGNFTPPPRGAAPAPVSGPEPTAAPPSGGGRFSPRNWRVPTRLNAILLIPVIVGLVMGGFQVKSSIDTWREAEDAENTARLVRASLSYADALYNERDSTAAPLLSGQGQDNPTVVAARKKTDQAAEVFNEAAAKMPKKAGLERRLKLFRDGEGGLQTLRAGAYTSSKFTGVKTEEGYTQVAHPLTEFANELGLGTGNITSYGRTVYAIELTKAALSLQRSIGMHLLIKPGPGLSSFASQKVALSSYAYLEGIAVEEYVGGGTAADAAKLDTAKKQIQTEGAALAKEAAAKNPNYVPPPSNPVVMVSSLAQLPSMDQSARESLAKDGITAENWWAVNTLKYNAYRQIETDLADTAVNEAAGIADDAKRDAFIVGAAVVVALLLAFILAGAVARQMSRSMRQLRNAAFGIAEQRLPMLVDQLSRTDPGRVDTRVAPIPINTKDEIGEVARAFDQVHREAVRLASEQALLRGNINAIFTNLSRRNQSLIEGQLTLITDLENNEADPDQLENLFRLDHLATRMRRNGENLLVLAGEEPGRRWDQPVPLVDVLRAASSEVEQYERIELSGVPEAEIHGRAVTDLVHLLAELLENATTFSSPQTKVRVTATRLPDGRIMIEIHDKGIGLTAEDFADINHKLANPPTVDAAISQRMGLFVVGRLSDRHGIRVQLRPSGEQAGTTSLVMLPDAITHGGGGEHQPANDEFTVSQIMPEQQYQGEDFNNGLPMRTAAELGFDDSRYAEVPDDIRELDPVGRSLMREERRAALEAQSHDQPPALQAPDPSYTEAFDGPQNAPQGGAQNGYDSNRNGFPEQQPAGYDQQTSYEEAQQAPYEEAQQAPYEEQRQPSYEEPGRPAYDEPYFAQNGGLPQNDVFSANGGYPEPAYAEQVQEEPAAVHAAAPETFSGFEERRHQDDWPQPDGYRGGYADQYAPETESVQAADVSEPDRVGFDRPGPAPANVGHELTDAGLPRRGSTGSGANGSNGTRHAHRESTASAPESNGGGDIWRSANDARWQQASQLRKPKAGGVTSSGLPRRVPKANLVEGAAESTPQGGPSVSRAPEDVRGRLSNLRRGVQRGRNAGSETNGQGFGSDSTYNQER
>NZ_CP041168.1|WP_004983065.1|6486244_6486658_-|roadblock/LC7-domain-containing-protein
MSQAAQNLNWLITNFVDNTPGVSHTVVVSADGLLLAMSEGFPRDRADQLAAVASGLTSLTAGASRIFEGGSVNQTVVEMERGFLFIMSISDGSSLAVLAHPEADIGLIGYEMALLVDRAGTVLTPDLRAELQGSLLN
>NZ_CP041168.1|WP_030315920.1|6485575_6486148_-|DUF742-domain-containing-protein
MATPPGGSSGNWSYGPGQGPNDGQNPNRYNFPSTPSHRQQPYAPQGPGPSPYDQPPAPRIQPVQPQRRSEPAPAGASNNPLVRPYAMTGGRTRPRYQLAIEALVHTTAQPHQMQGQLPEHQRICNLCREIKSVAEISALLTIPLGVARILVADLAEAGLVAIHQPGGDENAGGQPDVTLLERVLSGLRKL
>NZ_CP041168.1|WP_026248371.1|6485013_6485595_-|ATP-binding-protein
MDFASSSGGPSRSTTSAKIVVAGGFGVGKTTFVGAVSEINPLRTEAVMTSASAGIDDLTHTGDKTTTTVAMDFGRITLDQDLILYLFGTPGQDRFWFMWDDLVRGAIGAIVLVDTRRLADCFPAVDYFENSGLPFVIALNGFDGNQPYNPDEVREALQIGPDTPIITTDARHRADAKSALITLVEHALMARLR
>NZ_CP041168.1|WP_062026781.1|6484662_6484854_+|acyl-CoA-carboxylase-subunit-epsilon
MSTPDIRVEKGHAEPEEVAAITAILLARAAARPSETPSHPGHPKARWRRLEREGGFRAPHSWH
>NZ_CP041168.1|WP_141207118.1|6483009_6484605_+|acyl-CoA-carboxylase-subunit-beta
MTVLDEAPSESTGEPTDARGRVAELHEIRAAALAGPSEKATEAQHAKGKLTARERIELLLDAGSFQEVEQLRRHRATGFGLEAKKPYTDGVITGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIFQRNTKASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVKAVTGEEITQNGLGGADVHAETSGVCHFAYDDEETCLAEVRYLLAMLPQNNRENPPRVESSDAADRRGDVLLDLVPADGNRPYDMAKVIEEIVDDGDYLEVHERWARNIICALARLDGQVVGIVANQPSTLAGVLDIEASEKAARFVQMCDAFNIPIVTFLDVPGFLPGVDQEHGGIIRHGAKLLYAYCNATVPRISLILRKAYGGAYIVMDSQSIGADLTYAWPTNEIAVMGAEGAANVIFRRQIAEAEDSEAMRARMVKEYKSELMHPYYAAERGLVDDVIDPAETREVLIKSLAMLQSKHADLPSRKHGNPPQ
>NZ_CP041168.1|WP_141207117.1|6480512_6482858_+|polysaccharide-lyase-8-family-protein
MNTRRNPTPNPLVSRRTALLAAALLPTTALPAAPVRAAGAADPYDALRHRWLDIALGTGYDPTAEPYAGRLAETGGLARGFRAAMAPTPTSLWPGVPFDPPAGITQSYGRLWTMTRAHVQQGTGSTGDEDLLGAVLRGLDHLSATVYNPSTTRYGNWWEWQIGSPRLLMDITAALHDRLTDTRRAAACAAVDHFIPDALLTDYSGTSTGANRVDLCRSVALRGILGRAPERIALARDALSPVFPYVTKGDGLYADGSFVQHTRVAYSGTYGQVLLDGLGRLLTLLAGSEWEVTDPNRRTVLDSVEHAFAPLIHDGLVMDGVNGRAISRGHLKSDDRPVLRSDHFHGHGIVAAVALLAGGAGTAERERWYGLVKGWIERDTVTPVLTSPQFGVADLARLHTVAASPVPAAPAPVGHRLFAAMDRAVHRRPGFVAGIAMASDRIAAYECGNGENPRGWHTGAGMLSWWTGKRSDQYTDWYWPTVDWYRLPGTTVSTRRLPDRAGGEWGEPRPDVRWVGGTTDGEYAAIGQHLKGLESTLQARKSWFCLADAVVCLGAGITCTDGVPVETVVDNRNLGESGEQAFVRGPGWAHLDGHGGWLVPDAVHALREDRTGAWSDINTGGTAERRTRRWQTLWLDHGTDPVDATYAYVLLPGAARRTVAARAADRHWLSVLANDGTCQAVHVDRLGLTAANFWRPGTAGPLTTSAPASVLVRRTGRTATLCVAEPTRTGEPLEIVWNRPVRSVIRADDTVEVLAAGRLLRLRVTPGEVCATHVCEVALTG
>NZ_CP041168.1|WP_020138705.1|6496323_6496509_+|hypothetical-protein
MKTTMMFRNIANPRRTTLVHVKDAGELHTPEQPEHTLDLPAQTANPRRTVLMEIPVSAAAE
>NZ_CP041168.1|WP_141209460.1|6496606_6497476_-|hypothetical-protein
MVGCAAHEPSAGVASGASPSAPERIPSPSPSASESYTFRLPLAVYSYSDADYEVIRSAEQVLARDCMKDFGLSYTPAKNTAPAEAQDRRYGLTDRASAERYGYRMPPQPRTPKAKLTEDQIKVLYGNRSAPAAEAKNSELRYRGKKVPAEGCLGAAVLGFRKPYEDEAGAEAASRISTASYENSQKVPEVRAAFGKWSSCMKQKGYDYASPMEAMAAPAFVRGRVSAVEKDTAEADVSCKERTGLADVWFAAESSIQKDMIKTEAEALRRLGELHERKLRAARKILAGA
>NZ_CP041168.1|WP_141207121.1|6497576_6498017_-|hypothetical-protein
MKSKRKALSLAMAVSAAAVTVLGAAPVAHAEARETCPTWANDCAVFYYNSGLSGSRTAFTDDGVANLAGYTFLSPGNGKGQAVKNNAASFWNASVDHVATVFFNSNYSGACDTFAPLADADKLARTYNENASFDFNRNGTNCYKWN
>NZ_CP041168.1|WP_141207122.1|6498270_6499056_+|DUF2437-domain-containing-protein
MRIARFSIDGNVAFGAVEGDKPDELVLDIIKGIPFADFQLSGTKVPLSKVRLLPPVLPNKVVAYGRNYADHAKELGNEVPDVPFAFFKPSTSVIGPGDDIQYPSFSADVHHEAELAVVIGRMCREVPRERVKDVIFGYTCANDITARDVQKREKQWARAKGFDTSCPLGPWVETDLDLGTAADLTIQLTVNGEQRQLGRTSEMIHPIEDLIVNISEAMTLLPGDVILTGTPAGVGPLTVGDEVAVTIEGIGTLTNKVVKRG
>NZ_CP041168.1|WP_141207123.1|6499039_6500524_+|glutamate--tRNA-ligase
MSSVASAPVRVRFCPSPTGNPHVGLVRTALFNWAFARHHQGTLVFRIEDTDAARDSEESYNQLLDSMRWLGFDWDEGPEVGGPHAPYRQSQRMDLYKDVAAKLLDAGHAYHCYCSQEELDTRREAARAAGKPSGYDGHCRDLSAEQVSAYVAQGRTPIVRFRMPDETITFTDLVRGELTFTPENVPDYGIVRANGAPLYTLVNPVDDALMEITHVLRGEDLLSSTPRQIALYKALIELGVAQGIPQFGHLPYVMGEGNKKLSKRDPQASLNLYRERGFLPEGLLNYLSLLGWSLSADKDIFTTDELIAAFDIADVNPNPARFDLKKCEAINADHIRMLDVKDFTERCAPWLKAPFAPWAPEDFDETKWQAIAPHAQTRLKVLSEITDNVDFLFLPEPVFDEPSWTKAMKEGSDALLRTAREKLESADWTSPESLKEAVLAAGETHGLKLGKAQAPVRVAVTGRTVGLPLFESLEVLGKDTTLARIDAALEKLAA
>NZ_CP041168.1|WP_141207124.1|6500642_6501305_+|DUF4241-domain-containing-protein
MPMSPRDYTWLFTPGSSFAYESGTTGVIHVADGGELDLPTGQVVASDPFVYLGSGDIEPFTVSVPPGRYRVEAAVATLGRPDEPPADRPHLRVAAARVVIGTEPTTSWELALRPDQDPAELGDDEFYGYGVDAGTGCFYDASAEEAFPEAQEDEGPLWDAFENSDWSPGPHLVTSPSTGHTLVAFTSGWGDGFYPTWIGRSASGEVTCFLTDFFVVPDPS
>NZ_CP041168.1|WP_141207125.1|6501355_6502087_+|HAD-IA-family-hydrolase
MSIRAVVWDVDDTLFDYRGADRIGMGLHLAAEGLLAAHDSVEQAIDRWREVTDAQWARFSAGEVDFQGQRRDRVRVFLGEELTDAEADAWFQRYIAHYETAWSLFPDVLPALDALAASHRHAVLSNSSIHVQDHKLRVLGVHDRFEVILCAAELGVSKPEAGAFLAACDALELDPHQVAYVGDHPEIDGRGAADAGLLSVWIAREGLYATVEAPDGTHRIASLAELPSILGADTRFGAPSTFG
>NZ_CP041168.1|WP_007384919.1|6502960_6503677_-|IclR-family-transcriptional-regulator
MDNSSGVGVLDKAALVLSALESGPATLAGLVAATGLARPTAHRLAVALEHHRMVARDMQGRFILGPRLAELAAAAGEDRLLATAGPVLTHLRDITGESAQLYRRQGDMRICVAAAERLSGLRDTVPVGSTLTMKAGSSAQILMAWEEPERLHRGLQGARFTATALSGVRRRGWAQSIGEREPGVASVSAPVRGPSNRVVAAVSVSGPIERLTRHPGRMHAQAVIDAAARLSEALRRTG
>NZ_CP041168.1|WP_141207126.1|6503867_6505292_+|3-isopropylmalate-dehydratase-large-subunit
MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRQVRRLDLTIATEDHNTPTLDIDKPIADPVSRVQLETLRKNAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLVRPKTMAITVNGELPDGVTAKDLILAIIAKIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTFDYLEGRPHAPKGEDWDAAVAYWKTLKTDEDAEFDAEVVIEAAELSPFVTWGTNPGQGAPLSAHVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAELVKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPAAAGV
>NZ_CP041168.1|WP_141207127.1|6505297_6505891_+|3-isopropylmalate-dehydratase-small-subunit
MEAFTTHTGRAVPLRRSNVDTDQIIPAHWLKKVTRDGFEDGLFEAWRKDEKFILNQPERAGATVLVAGPDFGTGSSREHAVWALQNYGFKAVISSRFADIFRGNSLKNGLLTVVLDQKIVDALQELTEKDPEAEITVDLEAREVRAEGITASFELDENSRWRLLNGLDDISITLQNEDDIAAYEAKRPSFKPRTLQV

Crispr_ID: NZ_CP041168_12

• CRISPR_ID: NZ_CP041168_12
• CRISPR_location: 6511551-6511645
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_12

Consensus_repeat	Method
CGCGTCAGCCGTCCGTGACCCGC	CRISPRCasFinder

spacers of NZ_CP041168_12

>12.1|6511574|49|NZ_CP041168|CRISPRCasFinder
CGGGCCGGTCCGGATCTCCGTCCGTGATCCGCCGGGGCAGTCAGCGTCT

CRISPR arrays and Neighbor proteins around NZ_CP041168_12

CRISPR arrays

The CRISPR arrays of NZ_CP041168_12

>merge|NZ_CP041168|12|6511551-6511645|CRISPRCasFinder
CGCGTCAGCCGTCCGTGACCCGCCGGGCCGGTCCGGATCTCCGTCCGTGATCCGCCGGGGCAGTCAGCGTCTCGCGTCAGCCGCCCGTGACCCGC

>NZ_CP041168|12|12|6511551-6511645|CRISPRCasFinder
CGCGTCAGCCGTCCGTGACCCGC	CGGGCCGGTCCGGATCTCCGTCCGTGATCCGCCGGGGCAGTCAGCGTCT
CGCGTCAGCCGCCCGTGACCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141207133.1|6513645_6514467_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl|CDD|180561
NZ_CP041168.1|WP_141207132.1|6511737_6512220_-|DUF3515-family-protein	unknown	unknown	gnl|CDD|378794
NZ_CP041168.1|WP_141207135.1|6519928_6521764_-|HSP90-family-protein	unknown	unknown	gnl|CDD|237603
NZ_CP041168.1|WP_141207131.1|6510167_6511325_+|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234993
NZ_CP041168.1|WP_020138716.1|6506563_6507214_+|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|259858
NZ_CP041168.1|WP_141207136.1|6521932_6525163_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|236794
NZ_CP041168.1|WP_141207137.1|6525265_6525868_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl|CDD|367574
NZ_CP041168.1|WP_030315884.1|6512680_6513649_+|thiamine-phosphate-kinase	unknown	unknown	gnl|CDD|235583
NZ_CP041168.1|WP_141207130.1|6508313_6509078_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP041168.1|WP_020138726.1|6514671_6514857_-|50S-ribosomal-protein-L28	unknown	unknown	gnl|CDD|234736
NZ_CP041168.1|WP_141207127.1|6505297_6505891_+|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|179314
NZ_CP041168.1|WP_141209461.1|6515113_6516838_+|DAK2-domain-containing-protein	unknown	unknown	gnl|CDD|274671
NZ_CP041168.1|WP_141207126.1|6503867_6505292_+|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl|CDD|235490
NZ_CP041168.1|WP_028809826.1|6506195_6506426_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141207129.1|6507520_6508159_-|2-phospho-L-lactate-guanylyltransferase	unknown	unknown	gnl|CDD|274643
NZ_CP041168.1|WP_020138723.1|6512240_6512474_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366431
NZ_CP041168.1|WP_141207134.1|6516869_6519929_-|tetratricopeptide-repeat-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_007384919.1|6502960_6503677_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP041168.1|WP_141207128.1|6507319_6507511_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_062026769.1|6509074_6510085_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|234629

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141207133.1|6513645_6514467_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl|CDD|180561	PRK06427, PRK06427, bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed.	4.10447e-123
NZ_CP041168.1|WP_141207132.1|6511737_6512220_-|DUF3515-family-protein	gnl|CDD|378794	pfam12028, DUF3515, Protein of unknown function (DUF3515). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 166 to 214 amino acids in length. This protein has a conserved RCG sequence motif.	8.57736e-23
NZ_CP041168.1|WP_141207131.1|6510167_6511325_+|D-alanine--D-alanine-ligase	gnl|CDD|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	3.42091e-178
NZ_CP041168.1|WP_020138723.1|6512240_6512474_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|366431	pfam01037, AsnC_trans_reg, Lrp/AsnC ligand binding domain. The l-leucine-responsive regulatory protein (Lrp/AsnC) family is a family of similar bacterial transcription regulatory proteins. The family is named after two E. coli proteins involved in regulating amino acid metabolism. This entry corresponds to the usually C-terminal regulatory ligand binding domain. Structurally this domain has a dimeric alpha/beta barrel fold.	1e-08
NZ_CP041168.1|WP_141207136.1|6521932_6525163_+|DEAD/DEAH-box-helicase	gnl|CDD|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP041168.1|WP_141207137.1|6525265_6525868_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl|CDD|367574	pfam03602, Cons_hypoth95, Conserved hypothetical protein 95.	7.40377e-68
NZ_CP041168.1|WP_030315884.1|6512680_6513649_+|thiamine-phosphate-kinase	gnl|CDD|235583	PRK05731, PRK05731, thiamine monophosphate kinase; Provisional.	1.27389e-130
NZ_CP041168.1|WP_141207130.1|6508313_6509078_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.35981e-44
NZ_CP041168.1|WP_020138726.1|6514671_6514857_-|50S-ribosomal-protein-L28	gnl|CDD|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.49418e-23
NZ_CP041168.1|WP_141207127.1|6505297_6505891_+|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	6.74993e-126
NZ_CP041168.1|WP_141209461.1|6515113_6516838_+|DAK2-domain-containing-protein	gnl|CDD|274671	TIGR03599, YloV, DAK2 domain fusion protein YloV. This model describes a protein family that contains an N-terminal DAK2 domain (pfam02734), so named because of similarity to the dihydroxyacetone kinase family family. The GTP-binding protein CgtA (a member of the obg family) is a bacterial GTPase associated with ribosome biogenesis, and it has a characteristic extension (TIGR03595) in certain lineages. This protein family described here was found, by the method of partial phylognetic profiling, to have a phylogenetic distribution strongly correlated to that of TIGR03595. This correlation implies some form of functional coupling.	8.43809e-143
NZ_CP041168.1|WP_141207126.1|6503867_6505292_+|3-isopropylmalate-dehydratase-large-subunit	gnl|CDD|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP041168.1|WP_141207129.1|6507520_6508159_-|2-phospho-L-lactate-guanylyltransferase	gnl|CDD|274643	TIGR03552, F420_cofC, 2-phospho-L-lactate guanylyltransferase. Members of this protein family are the CofC enzyme of coenzyme F420 biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.83645e-40
NZ_CP041168.1|WP_141207135.1|6519928_6521764_-|HSP90-family-protein	gnl|CDD|237603	PRK14083, PRK14083, HSP90 family protein; Provisional.	0
NZ_CP041168.1|WP_020138716.1|6506563_6507214_+|HU-family-DNA-binding-protein	gnl|CDD|259858	cd13836, IHF_B, Beta subunit of integration host factor (IHFB). This subfamily consists of the beta subunit of integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms.	2.02373e-21
NZ_CP041168.1|WP_007384919.1|6502960_6503677_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.45656e-45
NZ_CP041168.1|WP_062026769.1|6509074_6510085_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	4.08165e-180

Protein sequences

>NZ_CP041168.1|WP_141207131.1|6510167_6511325_+|D-alanine--D-alanine-ligase
MSTENLPQSPEQPPRKPRVAVVFGGRSSEHGISVVTAGAVLKAIDRTKYDVLPIGITQDGRWALTADAPERMAITERRTPNVSELAESHEGGVVLPVDPANREVVYSEPGSVPKALGEVDVVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRVFTSFGLKVGPYVVIRPREWERDESAARKKIVDFAGEHGWPLFVKPARAGSSIGITKVDDLSGLDEAIAEAQSHDPKILVEAALRGREIECGVLEFEDGPRASVPAEIPPPQEHAYYDFEAKYIDSTPGIVPAPLTPEETAEVQRLAVDAFDAASCEGLVRADFFLTEDGEFVINEINTLPGFTPISMYPQMWEKSGISYPELVSRLIEAALRRSTGLR
>NZ_CP041168.1|WP_062026769.1|6509074_6510085_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MSKPVKAAVFGTGSWGTAFGMVLADAGCEVTLWARRPELAEAVNSTRTNPDYLPGVELPENLRATADAAEAARDAELTVLAIPSQTLRANLAEWTPLLAPDTVLVSLMKGVELGSAMRMSEVVEDVAKVGQDRIAVVTGPNLAREIAARMPAAAVVACTDEAVATRLQASCHTPYFRPYTNTDVVGCELGGAVKNVIGLAVGIADGMGLGDNAKGSLITRGLAETTRLGLAMGADPLTFSGLAGLGDLVATCSSPLSRNHTFGTNLGKGMTLQETIAVTKQTAEGVKSCESVLDLARRHGVDMPITETVVGIVHEGKSPVVAVKELMSRSAKPERH
>NZ_CP041168.1|WP_141207130.1|6508313_6509078_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MPRRRIGFWYRLAAVIAKPPLVVLIKRDWCGLENIPADGGFITAVNHNSHIDPFAYAHFQYNTGRVPRFLAKSGLFKKGFVGAVMRGTGQIPVYRESTDALSAFRAAIEAVERGECVAFYPEGTITRDPDQWPMIGKTGAARVALQTKCPVVPVAQWGANEVLPPYAKKLHLFPRKTHHVLAGPPVDLTRFYDKDMTQDLLKEATEVIMAAITAQLEIIRGEKAPGTAYDPRRERIEQRRRTQAQSGREGEKSK
>NZ_CP041168.1|WP_141207129.1|6507520_6508159_-|2-phospho-L-lactate-guanylyltransferase
MQWTLVIPLKPLARAKSRLSDTAGDGVRPGLALAFAQDTVAAALTCPAVRDVAVVTDDDLARRELAALGARIVPDEPLGGLNAALRHGASAVRSARPESALAALNADLPALRPLELARVLDAAAEFPRAFLPDAAALGTTLLAAAAGEELHPAFGPHSRRRHHASGAAELRLDDVDSVRQDVDTGEDLRAALALGVGPRTAAAAARLLIPGQ
>NZ_CP041168.1|WP_141207128.1|6507319_6507511_-|hypothetical-protein
MQATAYTYDPESRSGQVLLDDGTPVPFDAPAFDAGGLRLLRPGQRVRVETDGGKITLVTLQTF
>NZ_CP041168.1|WP_020138716.1|6506563_6507214_+|HU-family-DNA-binding-protein
MNKAQLVEAIADKVGGRQQAADAVDAVLDAIVRATVAGDRVSVTGFGSFEKVDRPARYARNPQTGERVRVKKTSVPRFRAGQGFKDLVSGTKKLPKNDVAVKKAPKGSLTGGASATVKKAAAKKATTAKTAAAKKTTAKKTTAKKTTATAKKTTAKKAPAKKATGTAAKTTAASKTAAKKTTAKKAPAKKATAKKAPAKKSAARTTTAKKATARKR
>NZ_CP041168.1|WP_028809826.1|6506195_6506426_+|hypothetical-protein
MEHDGQLELYAAVADQLKEAHARVRALQVPEGVRMALTRKLLVITAAAKHDVVEATRRLERFTADLDAGRIPEEER
>NZ_CP041168.1|WP_141207127.1|6505297_6505891_+|3-isopropylmalate-dehydratase-small-subunit
MEAFTTHTGRAVPLRRSNVDTDQIIPAHWLKKVTRDGFEDGLFEAWRKDEKFILNQPERAGATVLVAGPDFGTGSSREHAVWALQNYGFKAVISSRFADIFRGNSLKNGLLTVVLDQKIVDALQELTEKDPEAEITVDLEAREVRAEGITASFELDENSRWRLLNGLDDISITLQNEDDIAAYEAKRPSFKPRTLQV
>NZ_CP041168.1|WP_141207126.1|6503867_6505292_+|3-isopropylmalate-dehydratase-large-subunit
MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRQVRRLDLTIATEDHNTPTLDIDKPIADPVSRVQLETLRKNAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQPGMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLVRPKTMAITVNGELPDGVTAKDLILAIIAKIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTFDYLEGRPHAPKGEDWDAAVAYWKTLKTDEDAEFDAEVVIEAAELSPFVTWGTNPGQGAPLSAHVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAELVKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPAAAGV
>NZ_CP041168.1|WP_007384919.1|6502960_6503677_-|IclR-family-transcriptional-regulator
MDNSSGVGVLDKAALVLSALESGPATLAGLVAATGLARPTAHRLAVALEHHRMVARDMQGRFILGPRLAELAAAAGEDRLLATAGPVLTHLRDITGESAQLYRRQGDMRICVAAAERLSGLRDTVPVGSTLTMKAGSSAQILMAWEEPERLHRGLQGARFTATALSGVRRRGWAQSIGEREPGVASVSAPVRGPSNRVVAAVSVSGPIERLTRHPGRMHAQAVIDAAARLSEALRRTG
>NZ_CP041168.1|WP_141207132.1|6511737_6512220_-|DUF3515-family-protein
MIDFRRRLIGLPALLMLITIAGCSSADDGTRAAVPSPGTEVTELCENLDKALPSKVDGQDRRDPEPASALTAGWGDPAIILRCGVQRPSKMDDPEADGVEVDGVGWLLEKQDDGSFRFTTTLRKAYVEVTIPEKRTGDGMAPLVDLAPAVKKTIPAGIAD
>NZ_CP041168.1|WP_020138723.1|6512240_6512474_-|Lrp/AsnC-family-transcriptional-regulator
MVQAYILIQTEVGKASTVAETISKIPGIIQAEDVTGPYDVIVRAQADTVDDLGRMVVAKVQQVDGITRTLTCPVVHL
>NZ_CP041168.1|WP_030315884.1|6512680_6513649_+|thiamine-phosphate-kinase
MKGTVGELGEFGLIRELTSRLTTTPAVRVGPGDDAAVVAAPDRRVVASTDILLEGRHFRRDWSTAYDVGRKAAAQNLADIAAMGAVPTALLLGLVVPAELPVTWPSELMDGLRDECQVAGASVVGGDVVRGDTIMVSITALGDLRGQEPVTRAGAQPGDLVAVTGWLGWSAAGYAVLARGFRSPRAFVEAHRRPEPPYHAGPAAAALGATAMCDVSDGLIADLGHIAEASKVRIDVRSGAIDIPSQMNDIGQAVGVDPLQWVLTGGEDHAIVATFHPDVKLPARWKVIGEVLNPSALPQVTVDGAPWTSKGGWDHFGEDIEP
>NZ_CP041168.1|WP_141207133.1|6513645_6514467_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MRPPLVLTVAGSDSGGGAGIQADLKTMLALGVHGMSVVTAVTAQNSLGVQGAWELPVEAVRAQYRSVVDDIGVQAVKTGMLASAELVETVAELLGSTGVPAVVDPVGVSKHGDSLLASTALESMRRKLLPVATVATPNLDEVAQLTGVRVESEAGMREAADAVLSFGPAWVLIKGGHLSGDAVDLLTDGAEEHWLRAPRHDNRHTHGTGCTLASAIASQLAKGRSVPEAVADAKDYVTGAIASGFALGGGIGPVDHGWALKRDLTPGAPAVRC
>NZ_CP041168.1|WP_020138726.1|6514671_6514857_-|50S-ribosomal-protein-L28
MAANCDVCGKGPGFGNSVSFSHRRTSRRWNPNIQHVRTVIGGTPKRLNVCTSCIKAGKVSR
>NZ_CP041168.1|WP_141209461.1|6515113_6516838_+|DAK2-domain-containing-protein
MAQVPQTFFDALAVRTWCGLALRALGRAREEIDAINVYPVADGDTGTNLYLTAESAAAAVEAVFEAHNAHDLGKPALADAARAMAHGALIGARGNSGTILAQLLRGMAQVLAADSETPHTDGEGLRLALRQAADSARQAVAHPVEGTVLTVASAAADAAEHTDGDCGTVARAAYDGARAALAETPGRLAVLGRAGVVDAGGRGLVAVLAALVETFTGETPKAVPVAAGPEHARGVGATAVTSPEIVAEMSDVPATPLDECADGPETGGPAFEVIYLLEADDTAVARLRERLDGLGESLVVVGGDGLWNVHVHVDDAGAAVEAGVEAGRPYRIRITHFGVGDVHTTGAERPPRERAQRAVVAVVPGEGLAGLYAEAGATTVLARPGEPPASGELVQAVRRAHAREVVLLPNDADLRHTAAAAAEQARAEGIRVALIPTRSAVQGIAALAVHEPERRFDEDVVQMTSAAGATRHAEVVVAERQSWTMAGICQAGDVLGLIDGDVAVIGSDVTATAESVLDRMLSAGGELVTLVLGDEAPETVADHLETRVREAYLAVDTVVYRGGRQGAVLLIGVE
>NZ_CP041168.1|WP_141207134.1|6516869_6519929_-|tetratricopeptide-repeat-protein
MSGFDGEAAFDALRRAMAENSEEPEGPARNARAEQLLAEAEKLNIPLAVIEALGHQLKVYNYSSEKAKMFVPFARLLRMWDERPEDFDEYETHSLHWVFKWMTAGMLDQPHIPLAAMEKWLGEMEHRYRLAGHSERAVRSAEYSVAAHIGDRARAERAYAAWLAADRDAMADCHACELHEQGWWQVRQGRDAEALDLWAPVLEGEFTCAHEPHAALASSLAPLLRLGRLEEARANHLRGFRLVRSMESMRGAYADHVEFCALSGNEARGLELLAERPAYFTDDGHPRSRLDFMAVVTLLMDRLVELGPADRPVPGPAGRAWTAAELAAHAREEALALAARFDERNGTAHVSERARARMAQHPLVDRLPLGVRAARTVAAPPPAPPAPALAQEPGLPALIAEARRLSDTLRPNAVEAWAAVARAAQDVELDPRDRAEIADHEAMDRGPEGAALFERAAELYELAGDPGEALAAHARAAYVRALAGEVDEALTAVDGPYDEVLALYAADGTGVRQTASVVMSRARILMRQVQEAGEDGEGGEGGEGGILSEAERAVREVLALVEGRTEDDVRLAARVAEAQAMLAELAARTGDVESAAELFTRAAAGFVEAGLPWFAVEYEARLAGLLHHLGDLAGTERALRSALEHGGPHLEPVGRAQLRLQLAEVVGGRGLAEEAAEHALEAAHWADEAGEGRTLGAWARHQLGGYLVRLGRWAEAAEVLESALHDLRPETHGDGVVVQTQWWLGDCLSELGEHREAAERRLQAAEIARHWPEQHDHATLAHLAAESLGAAGLPAEADRAYARAGGLWREIGNVHGLIRSLRARAWLALRAEDGADAARELMARAVRECEAALGDAGSDEEARARLVGELGHTHRQFGDLLARSVSEDAEDDSIRAVLEEALTQVAESIVLFASLGEDALDARTGAELAAGWLAADLSRPEEAAARARAVLAAYGAPGSPSDDDTTERDRRDADDPTARDRRDVGGGTGPTRRDAGDATAQARRAEAAQMLALMEEQQD
>NZ_CP041168.1|WP_141207135.1|6519928_6521764_-|HSP90-family-protein
MDSQTSQSSQTPQVPQQPHTFQVDLRGLVDLLSHHLYSSPKVYLRELLQNAVDAITARRAEEPDAPARVRLYAEEGALRVEDSGVGLTEADVHNLLATIGRSSKRAEGLQEARSDFLGQFGIGLLACFVVAERIRVVSRSARTPDAPPVEWTASDDGSYRVRTLPADARPEPGTTVYLVARAGTGEWLAPGRVLQLARDFGSLLPYDVRVGEEAVTDLPAPWDRPYPSPANRRVALARHCHDLFGFTPLDSIELNVPLAGVRGVAYVLPSAVSPAQRATHRVHLKGMLLTERAEQLLPDWAFFVRCVLDTDSLRPTASRESLYEDETLAAVREALGERIRSWLTGLAAGDPERLGAFLSVHHLGVKSLARHDREMLRTMLPWLPFETTDGRLSLEEFAQRHPVVHFTRTVEEYRQVAPIASAQGIGVVNGGYTYDSDLVEALPSVRPGTVVTELDADTVTAHMDLVDPAEELALSGFLAAARAKLDPLGCDVVLRAFRPLSVPALHLDDRDARHEQARADAEEQADDLWAGILGSLRGSAPRARLVLNHLSPLVRRIGALGDPELIGTATESLYGQALLMAQRPLRPADSALLNRAFIGLLEWATNGEEGR
>NZ_CP041168.1|WP_141207136.1|6521932_6525163_+|DEAD/DEAH-box-helicase
MDLVPALEEPLKKVLGPATAKVMAEHLGLHTVGDLLHHYPRRYEERGQLTHLADLPLDEHVTVVAQVADARLHSFASAKAPRGKGQRLEVTITDGSGRLQLVFFGSGVHKPHKELLPGTRAMFAGKVSLFNRRLQLAHPAYELLRGADDEAAESVETWAGALIPIYPATAKLESWKIGKAIQTVLPSAQEALDPLPESLREGRGLVTLPEALLKIHRPHTKADIADAHARLKWDEAFVLQVALARRRHADAQLPAVPRKPSPDGLLTAFDDRLPFTLTEGQQKVSKEIFDDLATAHPMHRLLQGEVGSGKAQPLDSLVLTPVGFRRMGDLRVGDEIVVPDGEIALVDGVFPQGERDVWRLVLSDGSSVECDDEHLWIVGTSCGWHRGQAPKVMTTREIRRDTFRANGSSKWYLPAATPVDLGDDCGLPLDPYLFGVLLGDGSFRHHLRLSTVDAEIRDAVETAVAPECRLVPVSGSRCDYTIQLPLRAGGERNPVIQALRDLNLWGVTSHGKFIPGEFKNTSIKNRLAVLQGLMDTDGTVDKAGLSISFCSASRRLAEDVAWLVRSLGGRARILPKRSAFNVFVSLPDEYVPFRLRRKAERVGPRPKYNTFRRGVRAVEYVGRKPVQCISVAHPSHAYVTDNFTVTHNTMVALRAMLAVVDAGGQAAMLAPTEVLAQQHHRSIVEMMGELAEGGMLGGAEHATKVVLLTGSMGTAARRQAMLDLVTGEAGIVIGTHALIEDKVQFEDLGLVVVDEQHRFGVEQRDALRGKGKQPPHLLVMTATPIPRTVAMTVFGDLETSVLDQLPAGRSPIASHVVPAADKPHFLSRAWERVREEVENGHQAYVVCPRIGDEEDDPKKSGRKKSPEDEAEKRPPLAVLEVADQLTKGPLSGLKVEVLHGRMHPDDKDAVMRRFAAGETHVLVATTVIEVGVNVPNATAMVIMDADRFGVSQLHQLRGRVGRGSAAGLCLLVTEMPEASPARQRLNAVASTLDGFELSRIDLEQRREGDVLGQAQSGARTSLRVLAVIEDEEIIAEAREEATAVVEADPELKGLPGLRTALDALLDEEREQYLEKG
>NZ_CP041168.1|WP_141207137.1|6525265_6525868_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MTRVIAGRAGGRRLAVPPGNGTRPTSDRAREGLLSTWQSLLGGPLDGERVLDLYAGSGAVGLEALSRGASHTLLVEADARAARTIRENVKSLGLPGAEVRAGKAEQIIQQPAPAQPYDIVFLDPPYRVTDHDLREILLTLRAEHWLAPEALVTVERSTRGGEFAWPPGFEAVKARRYGEGTFWYGRAAMGDNASTCEDAR

Crispr_ID: NZ_CP041168_13

• CRISPR_ID: NZ_CP041168_13
• CRISPR_location: 7113707-7113822
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_13

Consensus_repeat	Method
CCACCACTCGCCCGGCGGCGGCACGCGTGAGAGCCGGC	CRISPRCasFinder

spacers of NZ_CP041168_13

>13.1|7113745|40|NZ_CP041168|CRISPRCasFinder
GGGCCGGGGCAGCGCGCCCCCTTTCCCGCGGCCCGCACCG

CRISPR arrays and Neighbor proteins around NZ_CP041168_13

CRISPR arrays

The CRISPR arrays of NZ_CP041168_13

>merge|NZ_CP041168|13|7113707-7113822|CRISPRCasFinder
CCACCACTCGCCCGGCGGCGGCACGCGTGAGAGCCGGCGGGCCGGGGCAGCGCGCCCCCTTTCCCGCGGCCCGCACCGCCACCACTCGCCCGGCGGCGGCACGCGTGAGGGCCGGC

>NZ_CP041168|13|13|7113707-7113822|CRISPRCasFinder
CCACCACTCGCCCGGCGGCGGCACGCGTGAGAGCCGGC	GGGCCGGGGCAGCGCGCCCCCTTTCCCGCGGCCCGCACCG
CCACCACTCGCCCGGCGGCGGCACGCGTGAGGGCCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141207508.1|7113827_7114619_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224332
NZ_CP041168.1|WP_141207511.1|7118326_7119349_-|hypothetical-protein	unknown	unknown	gnl|CDD|236122
NZ_CP041168.1|WP_141207504.1|7109388_7109928_+|hypothetical-protein	unknown	unknown	gnl|CDD|366659
NZ_CP041168.1|WP_141207499.1|7105115_7106261_+|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NZ_CP041168.1|WP_141207505.1|7109961_7110423_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP041168.1|WP_141207513.1|7128203_7129319_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP041168.1|WP_141207506.1|7110690_7111734_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380519
NZ_CP041168.1|WP_141207501.1|7107352_7108018_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|197666
NZ_CP041168.1|WP_141209502.1|7114758_7115658_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|131350
NZ_CP041168.1|WP_141207509.1|7115844_7117107_-|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl|CDD|274452
NZ_CP041168.1|WP_141207500.1|7106392_7107343_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378976
NZ_CP041168.1|WP_141207502.1|7108000_7108453_-|glyoxalase	unknown	unknown	gnl|CDD|319901
NZ_CP041168.1|WP_141207507.1|7111985_7113569_+|carboxylesterase-family-protein	unknown	unknown	gnl|CDD|365897
NZ_CP041168.1|WP_141207503.1|7108454_7109087_-|VOC-family-protein	unknown	unknown	gnl|CDD|379203
NZ_CP041168.1|WP_141207512.1|7121945_7122665_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379115
NZ_CP041168.1|WP_141207510.1|7117368_7118208_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224332
NZ_CP041168.1|WP_141209504.1|7123299_7128099_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|225858
NZ_CP041168.1|WP_141209503.1|7119345_7121610_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP041168.1|WP_062021719.1|7117126_7117372_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|179197
NZ_CP041168.1|WP_141207498.1|7103231_7104866_-|DNA-alkylation-response-protein	unknown	unknown	gnl|CDD|183199

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141207508.1|7113827_7114619_-|helix-turn-helix-domain-containing-protein	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	3.33059e-51
NZ_CP041168.1|WP_141207511.1|7118326_7119349_-|hypothetical-protein	gnl|CDD|236122	PRK07877, PRK07877, Rv1355c family protein.	8.49231e-07
NZ_CP041168.1|WP_141207504.1|7109388_7109928_+|hypothetical-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	0.000718623
NZ_CP041168.1|WP_141207499.1|7105115_7106261_+|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	1.98743e-44
NZ_CP041168.1|WP_141207505.1|7109961_7110423_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	2.72126e-08
NZ_CP041168.1|WP_141207513.1|7128203_7129319_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	4.58795e-49
NZ_CP041168.1|WP_141207506.1|7110690_7111734_-|substrate-binding-domain-containing-protein	gnl|CDD|380519	cd06296, PBP1_CatR-like, ligand-binding domain of a LacI-like transcriptional regulator, CatR which is involved in catechol degradation. This group includes the ligand-binding domain of a LacI-like transcriptional regulator, CatR which is involved in catechol degradation. This group belongs to the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.5134e-94
NZ_CP041168.1|WP_141207501.1|7107352_7108018_+|helix-turn-helix-domain-containing-protein	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	3.34992e-13
NZ_CP041168.1|WP_141209502.1|7114758_7115658_+|helix-turn-helix-domain-containing-protein	gnl|CDD|131350	TIGR02297, AraC-type_DNA-binding_domain-containing_protein, 4-hydroxyphenylacetate catabolism regulatory protein HpaA. This putative transcriptional regulator, which contains both the substrate-binding, dimerization domain (pfam02311) and the helix-turn-helix DNA-binding domain (pfam00165) of the AraC famil, is located proximal to genes of the 4-hydroxyphenylacetate catabolism pathway.	2.25758e-21
NZ_CP041168.1|WP_141207509.1|7115844_7117107_-|beta-ketoacyl-ACP-synthase-II	gnl|CDD|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_CP041168.1|WP_141207500.1|7106392_7107343_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	1.76388e-41
NZ_CP041168.1|WP_141207502.1|7108000_7108453_-|glyoxalase	gnl|CDD|319901	cd07235, MRD, Mitomycin C resistance protein (MRD). Mitomycin C (MC) is a naturally occurring antibiotic, and antitumor agent used in the treatment of cancer. Its antitumor activity is exerted primarily through monofunctional and bifunctional alkylation of DNA. MRD binds to MC and functions as a component of the MC exporting system. MC is bound to MRD by a stacking interaction between a His and a Trp. MRD adopts a structural fold similar to bleomycin resistance protein, glyoxalase I, and extradiol dioxygenases; and it has binding sites at an identical location to binding sites in these evolutionarily related enzymes.	5.18381e-59
NZ_CP041168.1|WP_141207507.1|7111985_7113569_+|carboxylesterase-family-protein	gnl|CDD|365897	pfam00135, COesterase, Carboxylesterase family.	2.89787e-107
NZ_CP041168.1|WP_141207503.1|7108454_7109087_-|VOC-family-protein	gnl|CDD|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.53545e-44
NZ_CP041168.1|WP_141207512.1|7121945_7122665_+|TetR-family-transcriptional-regulator	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	4.61482e-14
NZ_CP041168.1|WP_141207510.1|7117368_7118208_-|helix-turn-helix-domain-containing-protein	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	3.73723e-53
NZ_CP041168.1|WP_141209504.1|7123299_7128099_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	6.94674e-168
NZ_CP041168.1|WP_141209503.1|7119345_7121610_-|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	6.2209e-87
NZ_CP041168.1|WP_062021719.1|7117126_7117372_-|acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.29651e-25
NZ_CP041168.1|WP_141207498.1|7103231_7104866_-|DNA-alkylation-response-protein	gnl|CDD|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	7.51334e-176

Protein sequences

>NZ_CP041168.1|WP_141207507.1|7111985_7113569_+|carboxylesterase-family-protein
MAAVRTDPVVSTPYGAVRGRHEDGVAVFRGIPYAAPPFGPNRFRPPVPPEPWDGVRDTVDFGPTAPKPPYSEAFAHYLSDPFVPGEDCLNLNVWTPDPGPGARLPVLVWLHGGALTRGSSAVPVYDGHAFARDGVVFVSVNYRLGVEGYGLFPDAPANPGLRDQLAALRWVHETIEAFGGDPGRVTLAGQSAGAISIGALLAAPQAQGLFRRAVLQSGPPEASDRDKVRRMVRRMATRLKVPATAAAFAEVDRELLLRTQAEVGRLSSPVLGGPAFGIVIDGDLVPRDPLEALVEGSVAREVELMLGWTSDEYRLWLVPGGLLERVDRLGPVALAGAMARCHCGSEVVRGYRALHPDAGTADIVGQMVTDHLLRIPLHRLAEARPGSSYVYEFAWPSNLPDLGACHALELGFVFDTGAVPESAKLAGEGAPAELADAMHGSWVRFATDGDPGWRPWDATHPVQIFGKGDPYVDSGPRDRDFAVWTADTTTKETAPVSEPAEGWPARTAELRSVVRRLRRTGLARRQH
>NZ_CP041168.1|WP_141207506.1|7110690_7111734_-|substrate-binding-domain-containing-protein
MVRTGSASVAAGPTLAVVAREAGVSVPTASKVVNGREDVAPETRRRVTEALDRLGYVRRPRFDAAKPSGLVDLVVHSLETSWSGAVLHGVEAAAHDAGLEVVVSAGLTRNRAGRPERGWLDKLTGRGSSGVLFNLAELSPTQYGWLDQHRIPYVLIDPVLEPPAGVVSVGAANWQGGVTATEHLLALGHERIAVVAGHRRKMCSSARVAGYRSALAAAGVRQRAEYVRLAGFDESTAHRRTLELLDLPEPPTAVFVCSDSMALGVYAALAERGLKVPDDMSVVGFDDLPEARWATPGLTTVRQPLSEMAATALRLLVRMMEGDRPESTRTELSTRLVERASTGAPRD
>NZ_CP041168.1|WP_141207505.1|7109961_7110423_-|helix-turn-helix-domain-containing-protein
MTRWRPLPDALPREARHLVEQLRQLKDRTDLSLAELARRTAYSKSSWQRYLSGAKQPPRGAVRALCRVAGADQARLLALWELAAPVWPYGPVGPPVPARISADEVPEAVVSDAVAEAVPGPEHRRWRAAALVAFAVIVLLVAGVLWAWPSGSG
>NZ_CP041168.1|WP_141207504.1|7109388_7109928_+|hypothetical-protein
MSMRKRAAATVTAVLVGAGTIGLAVAPAAEAAPYYGIDGGGVVSDDFQDEENLGVDDHANGNATALWQSVLYADGAKWQDDDGDWHNFAKSRIDGSFGPETESATQWWQERYGLTDNDGVVTDQSWEFAQQWLHGPFSGGVVRYDGDKRDVDFKRVGGKYRVKLKGTGSWRNAYYDQVG
>NZ_CP041168.1|WP_141207503.1|7108454_7109087_-|VOC-family-protein
MNAIPAGLDHLVLATPDLAATVADFTRRTGVVPAPGGVHVGRGTRNHLVALGGTAYLEIVGPDPEQPEPTGPRPFTVDTLPTARTVTWAISPPDLDAAVAAARSRGYDPGEIRPMSRRRPDGTLLKWRLTDGDTQHPSGLVPFLIDWGASPHPTASGLPNAPLLSLAATHPAPDEIRPLLAAVGTDLRLAEGPVGLSFTVDTPRGPVSFG
>NZ_CP041168.1|WP_141207502.1|7108000_7108453_-|glyoxalase
MSDSFKTAPGGAVYRAGMTPRFDAIGLVASDMAASVAFYRRLGLPFPEGAETQPHAEAELPGGMRLMLDTEETVRSFHPGWRAPAGGSRTALALRCDSPAEVDAVYERLVGEGAHGELKPWDAVWGQRYASLHDPDGNGVDLYAPLSGGE
>NZ_CP041168.1|WP_141207501.1|7107352_7108018_+|helix-turn-helix-domain-containing-protein
MYTERASRLAGAVLWTGDGAGRVLPDGCMDLLWNDGRLLVAGPDTRAYVTEGAPSTWVGLRFHPGSAPAFLGVPAHELRDLRVELADLWPASEARRLGSRVAASADPATALEDIALERAAPADPVLRALVASLDAGRPVGVTADELGLGPRQLHRRSLVAFGYGPKTLARILRLQRALALARAGVPYAETAARCGFADQAHLARDVRELTGVPLTRLLAAG
>NZ_CP041168.1|WP_141207500.1|7106392_7107343_+|helix-turn-helix-domain-containing-protein
MDALAGLLEGPRARGAFMIRACFDPPWAVRVEDRAPLTVMLMVRGEAVVLPDTGQSVRLRPGDLAIARGPAPYTCADAPDTAPQALILPGAECRHPDGRTLNGSMDLGVRSWGDRLNGGTVLLIGTYLVDGEISSRLLDALPPLLSLTTDVWECPLTPLLMAEIVRDEPGQEVVLDRMLDLLVIAALRAWFSRPEAEAPAWYAALADPVVGRVLRLMQDDPAHAWTVASLAAKAGVSRAALARRFTELVGEPVMAYLTGWRLALAADRLREGTATLDAIARQVGYGSAFALSSAFKRGYGVSPQEFRTRAAGARTA
>NZ_CP041168.1|WP_141207499.1|7105115_7106261_+|YihY/virulence-factor-BrkB-family-protein
MQAASESPRQPSGRLHRARALYRNVSKRRTAWLLLKDTVNSCIEYRILGLAAEAAFFSLLSVPPLLLSLIGLLGYVDDWTGTDSISSLEANLLAAARTVLSDKGVRQIAQPILDDVMKGGRPDVISVGFLFALWSGSRAVNVFIDTITVMYGLDGVRGIVKTRLVAFALFIAALLIGSVALPLMVAGPDAVVRIVPWSTTVVQVLYWPVVIILSVAFLTTLYHVSVPVRSPWIEDVPGALVALAMWVLGSFLLRIYLQSTIEGATIYGSLAAAVAVLLWIGVSAFAVLVGAAVNAAIDRVWPAAATAAARAANERVREAQVAEYVARAAAGVRDTDVDPDDPDMPSEFPERWSRFLPPEDVTSRLRTHAKSTHPPHKPEGS
>NZ_CP041168.1|WP_141207498.1|7103231_7104866_-|DNA-alkylation-response-protein
MAGTTHTVTNQPPPLTGYDVYGADLALKEAVARHLDPDLLDEVDGELSALGRACGSAQVQEWGAQANENPPRLRTHDRHGHRVDEVEFHPAWHRVLGKGVAAGLTAAWARPGGHVRRAAAFLLWTQVDAGNCCPLSMTHAAVPALRTDPDLAAEWEPRLTSMVYDRELRPAHLKAGALFGMGMTEKQGGSDVRAATTTARPFPDGETYELTGHKWFCSAPMSDGFLVLAQAPGGLTCFLVPRVLEDGTRNPFLLQRLKDKLGNRSNASAEVEFEGTWGRRVGDEGRGVRTIIEMVAATRLDCALGSAGLMRQAVAQAIHHCTHREAFGGKLVDKPLMRNVLADLALESEAATTLALRLAAAYDKGDEQERAFLRIAVPVAKYWITKRCTPLVTEAAECLGGNGYVEESGLPRLVRESPLNSIWEGAGNVQALDVVRALKREPQALNAYLLEIGRTRGADHRLDAAVKSLFTELADLEGIEGRARHLTERLALVLQGSLLVRHAPPEVADTFCASRLGGDSGTSFGTLPATLDLEKVVDRARPQA
>NZ_CP041168.1|WP_141207508.1|7113827_7114619_-|helix-turn-helix-domain-containing-protein
MTTPHAGTPERSLVDRALSVLSAFDRQNRTLTLSDISRRSGLPLATAHRIVNRLHSWGALERGEEGSYSIGLRLWETGTLAPRCSPLAEAALPHLMDLRARTSAGALLVIRDGLEGVCLAIAWSGPGSPVCLPESGDRMPLHACAAGLVLLAHADDAVQNHVCESPLRVYTPTTPTHGAALRQALAKVRRDGYAVTHRTLDPDCASLSFPVRGPGRAVVAAVAVVAPADTFQPAKVAPLVSAAADAVSQHARSTTLRPPRTTP
>NZ_CP041168.1|WP_141209502.1|7114758_7115658_+|helix-turn-helix-domain-containing-protein
MVDFARLPIPVVPYTPVCRSGSGISVMSLEDLLEKVPQTLLSAPHRLGFHEILLVTEGIGMFSIDSTRMECGPGSLLWLRPNQIVRYAPQPGMKGEVVLFTEAFPLPLQATVGTLDDVLRPSFWQLEEPETGQLGRVLDLLREEFRRTERVMGEHILQHLLSVVLLTVTRFCRSRQACRLAHDEIDHRELELFQRFRQDLDRSFHHTRRVEYYATALNCTSHALSRACRTVVGTSAKGVIDARVALEARRLLAHTRLPIGAVARQLGFTEVSNFTKFFIRLVQMTPGAFRRVHGVNFDG
>NZ_CP041168.1|WP_141207509.1|7115844_7117107_-|beta-ketoacyl-ACP-synthase-II
MFSKDRKVVVTGVGATTPLGGDSRSTWQGLLSGRSGVRLLTHAWAAETPVRIAAEVAVEPTELLPRPEARKLDRSAQFALVAAREAWADAGFTGPAGTDGTADPDRLGVVVASSIGGVISLLHQHDVLRQQGVRKVSPHTIPMMLPNTQGANVGLALNARAGVHSPVSACASGSESVGYGIDMIRTGRADIVVAGGTEAAIHPLTIAGFGNMMAMSKRNDDPAAASRPYDRARDGFVMGEGAGVVVLESAEHAERRGARVYAEAVGQGLSADSHHITQPEPSGRGIVAALSGLLDSCDLVPDQVVHVNTHATSTPKGDVSEVRALRKVFGEAMDHIAVSATKSMTGHLLGAAGGVESVATVLALHHRLAPPTINIDDLDPEVDADIVRGEPRPLPGGRIAALNNSFGFGGHNVVLAFRTV
>NZ_CP041168.1|WP_062021719.1|7117126_7117372_-|acyl-carrier-protein
MNTVQEEVRSGLADIVNEIVGVPLDEVRPEQSFADDLDVDSLSMVEVVVAAEERFGLTIPDQAAAGMKTVGDAIGYIVANR
>NZ_CP041168.1|WP_141207510.1|7117368_7118208_-|helix-turn-helix-domain-containing-protein
MSVPSPASDRSVVERTLSVLGAFDTGNVRLTVSEISRRSGIPVATAYRIVAKLLSWGALERAEDNRYTIGLRLWEIALLAPRHSDLRSAAVPHMFELRAVTRSAVLLSVRDGNEGICLESVSGTARPLHRSWSRGHRFPLHATACGRVLLAAADDITWEEIHTLGLGPHTPRTVTDPALLRGLVEQGRRQGFAVCDGELLDGVVEVAAPLYDADGTAVGAVGLVTDRARTSHDRDRASRVHDLTRPLLTAAGRISRSLALRNRTEGQHHSSTDKQRSRT
>NZ_CP041168.1|WP_141207511.1|7118326_7119349_-|hypothetical-protein
MTDTESTPVRSMDRLREIAGVAARAANAHNTQPWELRFRADHVEVGWRTQYALGPSDPAHRDLRLSLGTYVESLLICAAEAGIPVRYEPDFDADATRVGRLRPDAWPTASPRSVADVEGRRVWRGAWKREQVPAQTLHRARRTAEEAGFRVAVVPTQAARPLLVRAYHWFFGDAGIAAELLAWARLSPRHPEYRRDGLNDVMLVLSRAEALAMRMFFAPPVYRALRPLGLVRLLTTLSSGATRGDGVVLVILGKGHDPADEVEAGRLVTRLWLDLFRDGIHVHPQSHVIDCPGTVGDLARLCGATDGERPLVFFRVGYPATDPAARPRHPRRESAEHISA
>NZ_CP041168.1|WP_141209503.1|7119345_7121610_-|MMPL-family-transporter
MVTSVPPGSARTNRRGPWFTLLAGLLFLLVAGAASAGVLTHLKSGGFDDPGSDSVAAAKALERSFPDSQPNLIVLVKDTENGIDGAPARAEADAVRKAVSGTSGARIVASWFETPDPSLRSGDSALILVRIDGDENESMRTADDLHEELSDTDGGVSVSFGGITAVNDDMNKQVEKDIVAAETIAIPITLLLLVLVFRGLVAALLPMLLSVLTIVGALAAVNVTAQFTDVSVFAVNLITALGLGLSVDYSLLIVTRYREERAAGRTDEEALRITRATAGRTVAVSGGVVGAALATLLVFDQYFLRSFAVAGIAVVLGAVLGSLYLLPAALRLLGHRIDALGGRRRRPPAPPAGTFWGRVAGLAFRRPALLATPVIALLLLMAVPFAGAQFGVPDERVLPEGAESRVVNEAVRADFGAGDDRALNVVSEDWKATQAQLGQYAAALSKVTGVTRVVGSAGVFQDGSRVAALDPAAAAGYRSEGAVRLQVQTDVVPYSEKGGDLARAVRAVAPPGGSEVLVGGQAAQLVDITHSIAAKLPLAIVLISVLSLLFLFLLTGSVLMPVKALLFNALSLVGILGVAVWIFQDGHLSGLLGFTPSPLAVSMPVLVFCIAFGLSMDYEVFLVARIKERFDRTGRLESSVREGLGASGPVITAAAAILAVSFFAMLSSGVSLIKMYGLATGLAIVVDAVLVRGVLVPAFMRAVGPYNWWAPAPLKALHRRFGISESAEPGTAPAAAAPSSDRSGTAPQTTGSRP
>NZ_CP041168.1|WP_141207512.1|7121945_7122665_+|TetR-family-transcriptional-regulator
MGVIQGAKDRARAEVAGAIKDQARRQLAAEGAARLSLRAVARELGMVSSALYRYFPSRDDLLTALIVDAYNALGDTAEEAVERVGTDDWMRAWSAVCRAVRRWALDHPHEYALIYGSPVPGYAAPQDTVAPASRVALVLLAVAQSAHEAGALAEPDVPGADCRSVLADDVRLLLREPGRTLPERAAPRLAAVWAQLFGLISFEVFGQYNAVIEDREALFEATVLVLAHQVGLRPAGQDA
>NZ_CP041168.1|WP_141209504.1|7123299_7128099_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MSCRFPGAVNIDEFWKILMNAEPQFSAVPANRWDHSVYHRPGDFREPHGVYTDQVAFLPEADRFAPAHYGIPPRRARAMDPQAKLFVDLAREAIQDAGWERDGFDRAGTGVFAGVTSLDHRDISVSRISANLLADGSFHDGETDPELLGRLHRATDSALMPFNSFTIPGCLANMVPCTVSEVLDLGGPSVSLDAACSSALVALDAAIRSLRSGACSIALVGGVYLGLSPTPLVGFSRAGALSRQGVCRPFDERADGFVLGEGGATLVLRPVEDALAAGDRIYAVVTGVGSANDGRGGGPMTPQAQGQLAALRAAYRDAGADPGEVGLLEAHGTGTPVGDRTEIEAIGLLRAESDATTPCYVSSSKALIGHTLSAAGAAGLVKAALAVHHGVVPPQPAGTQVADVLDLDSSGLRLTTSPQAWPHDEVRRAGVSSFGFGGTNVHAVLEGAPRVAPAPAQGEHLPEGGNLPDDPWLILLSAGSVADLARHAEEVGNAVAADPEATPADVSRTLGRRELLTARLAFTAADRTELLDGLRLAAERLAQGALGEIAPGIHAAARPLPAEERRIAFAFPGQGSQRPGMLADLVRRFPVPAARAAELIEVTAEESQTVPSVLPGLLTRPHAPGDSEAQAMLTVTDMCQPALGITGAGTVGLLAACGIEPDVTVGHSVGEFPAAVAAGALTADEAVRFMTRRGAVLASAVPSGSGAMLAVQAPVAEAERLAEAVAGVWPACYNHDGQLVFSGSTETVEELREHCAAQGVTTVLLRVSHAFHSPLVAAADEEMSETIAALPLTVPTRTFVSAVSGRVCRDPQETKDLWARHNTAAVRFTDAVRSVAASGARFLVQVYGGDTLLRMARNNEAGASLETLALSTGRPDACRALLTTLGRLAVAGAPLDPTPLLPSEGRLLSLPPSPLATSVYSVRTGGSLRERSVVIPSPAAARPAAVAVTGTAGTAPAAPAGDTEAVAAHGSGTQSAAAVPLAHGASQPPLRTVIPSPLPTSPIGEPRMSGLIEFLHAQVALLQSFDPAGRGLPGPALPTITLPVTEPAVTHTVAAPVPPALPAAPSTVTADEVRAVVYAGIAKVSAYPEDFLRPEQVFATDLGFDSIMLAELATRLRAQWPDLAMPAADMMDIASIGDLVTAVHTRLDDRPGTRPAASPTPSEAPAPATETPATARAAAPARPTPAAPVEPSRRPVDRREVADVRTFPEVLASLERKRGLETSGAVNPYFLPHEGTIRDTTRVGDRELISFSSYNYLGLSGHPEVAAAVREAVERYGSSVSAARILSGNRPLHMELDRGLADLVGAEDAVSLVSGHATNVTVIGHLMGPQDLILHDALAHDSIIQGCRQSGAARQPFPHNDLVALDRILDHVRDNYRRVLIVVEGVYSMDGDTADLPALIAVKQRHDALLMVDEAHSIGVMGKTGGGMAQFSGVNPDDVDVWMGTLSKSLASCGGYVAGRHELIEHFRYTLPGFVFSAGLPPASTAAALTALRLIREEPERVTRLHDNSALFLRLAAEAGVDVGTSEGTPVVPAITGDSQKALHLADRLYARGISANPILHPAVEERLARLRFFITSEHTEEQITTAVNILGEELARLS
>NZ_CP041168.1|WP_141207513.1|7128203_7129319_+|Gfo/Idh/MocA-family-oxidoreductase
MTEPIRVGVIGAGPERGWARMSHLPALTASPDYELTAVATTRSGSARRAAELYGARHHFTDPARLSGHPDVDLVVVAVRTPDHAALVEAALEAGKHVYCEWPLARTTKEAEVLASAAEQAGVHHAVGLQARHAPAVRHARHLLTSGAIGRITGVDVYAARAKGAGGTVTSDAVYTLDRRNGAGTLEVAGGHTLDLLEHLCGSMGRLSALLSVQQPRLTVSDTAESVGVTGADHVLIGGLLVTGVPVSVHVHDGKTGHPRTRLEFTGTRGSLALVSEGPAAGHGIQVSDIHLYEAPAGDTWREVPVPPAHRTAVDVPDTAVRNVLELYTALARDIRTGSRTVPDFETGLRLHLLLDTVRSAHRTGACQAREV

Crispr_ID: NZ_CP041168_14

• CRISPR_ID: NZ_CP041168_14
• CRISPR_location: 7255157-7255240
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP041168_14

Consensus_repeat	Method
GGCCGCCCTGCACCGGCAAGGCG	CRISPRCasFinder

spacers of NZ_CP041168_14

>14.1|7255180|38|NZ_CP041168|CRISPRCasFinder
AGGGAGCGCCCGAGGGTGGCGACTCCTTGGCCTTCTGC

CRISPR arrays and Neighbor proteins around NZ_CP041168_14

CRISPR arrays

The CRISPR arrays of NZ_CP041168_14

>merge|NZ_CP041168|14|7255157-7255240|CRISPRCasFinder
GGCCGCCCTGCACCGGCAAGGCGAGGGAGCGCCCGAGGGTGGCGACTCCTTGGCCTTCTGCGGCCGCCCTGCACCGGCAAGGCG

>NZ_CP041168|14|14|7255157-7255240|CRISPRCasFinder
GGCCGCCCTGCACCGGCAAGGCG	AGGGAGCGCCCGAGGGTGGCGACTCCTTGGCCTTCTGC
GGCCGCCCTGCACCGGCAAGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041168.1|WP_141207616.1|7263200_7264580_+|8-oxoguanine-deaminase	unknown	unknown	gnl|CDD|236184
NZ_CP041168.1|WP_141207606.1|7251781_7253449_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341278
NZ_CP041168.1|WP_141207604.1|7247874_7250691_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|226415
NZ_CP041168.1|WP_141207610.1|7258771_7259662_-|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl|CDD|130569
NZ_CP041168.1|WP_141207602.1|7243692_7244853_-|magnesium-and-cobalt-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
NZ_CP041168.1|WP_141207600.1|7240485_7240974_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP041168.1|WP_141207601.1|7241068_7242595_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP041168.1|WP_141207603.1|7245001_7246231_+|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377630
NZ_CP041168.1|WP_141207611.1|7259693_7260515_-|TIM-barrel-protein	unknown	unknown	gnl|CDD|163190
NZ_CP041168.1|WP_141207607.1|7253492_7255079_+|AMP-binding-protein	unknown	unknown	gnl|CDD|236236
NZ_CP041168.1|WP_141207614.1|7261869_7262265_+|hydroxyisourate-hydrolase	unknown	unknown	gnl|CDD|376352
NZ_CP041168.1|WP_141207605.1|7250834_7251665_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_CP041168.1|WP_020133468.1|7246867_7247659_-|serine-protease	unknown	unknown	gnl|CDD|238113
NZ_CP041168.1|WP_141207612.1|7260900_7261260_+|transcriptional-regulator	unknown	unknown	gnl|CDD|379117
NZ_CP041168.1|WP_141207609.1|7256346_7258131_+|glyoxylate-carboligase	unknown	unknown	gnl|CDD|183066
NZ_CP041168.1|WP_141207608.1|7255339_7256152_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP041168.1|WP_062238673.1|7260652_7260904_+|hypothetical-protein	unknown	unknown	gnl|CDD|376658
NZ_CP041168.1|WP_141207615.1|7262269_7263190_+|urate-oxidase	unknown	unknown	gnl|CDD|274554
NZ_CP041168.1|WP_141209512.1|7243067_7243613_+|kinase	unknown	unknown	gnl|CDD|235858
NZ_CP041168.1|WP_141207613.1|7261344_7261854_+|2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline-decarboxylase	unknown	unknown	gnl|CDD|184333

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP041168.1|WP_141207616.1|7263200_7264580_+|8-oxoguanine-deaminase	gnl|CDD|236184	PRK08203, PRK08203, hydroxydechloroatrazine ethylaminohydrolase; Reviewed.	0
NZ_CP041168.1|WP_141207606.1|7251781_7253449_+|AMP-binding-protein	gnl|CDD|341278	cd05974, MACS_like_1, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. MACS enzymes are localized to mitochondria.	0
NZ_CP041168.1|WP_141207604.1|7247874_7250691_-|AAA-family-ATPase	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.99695e-18
NZ_CP041168.1|WP_141207610.1|7258771_7259662_-|2-hydroxy-3-oxopropionate-reductase	gnl|CDD|130569	TIGR01505, 2-hydroxy-3-oxopropionate_reductase, 2-hydroxy-3-oxopropionate reductase. This model represents 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60), also called tartronate semialdehyde reductase. It follows glyoxylate carboligase and precedes glycerate kinase in D-glycerate pathway of glyoxylate degradation. The eventual product, 3-phosphoglycerate, is an intermediate of glycolysis and is readily metabolized. Tartronic semialdehyde, the substrate of this enzyme, may also come from other pathways, such as D-glucarate catabolism.	3.15905e-149
NZ_CP041168.1|WP_141207602.1|7243692_7244853_-|magnesium-and-cobalt-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	7.2543e-157
NZ_CP041168.1|WP_141207601.1|7241068_7242595_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.00681917
NZ_CP041168.1|WP_141207603.1|7245001_7246231_+|winged-helix-DNA-binding-domain-containing-protein	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	3.16335e-60
NZ_CP041168.1|WP_141207611.1|7259693_7260515_-|TIM-barrel-protein	gnl|CDD|163190	TIGR03234, OH-pyruv-isom, hydroxypyruvate isomerase. This enzyme interconverts tartronate semi-aldehyde (TSA, aka 2-hydroxy 3-oxopropionate) and hydroxypyruvate. The E. coli enzyme has been characterized and found to be specific for TSA, contain no cofactors, and have a rather high Km for hydroxypyruvate of 12.5 mM. The gene is ofter found in association with glyoxalate carboligase (which produces TSA), but has been shown to have no effect on growth on glyoxalate when knocked out. This is consistent with the fact that the gene for tartronate semialdehyde reductase (glxR) is also associated and may have primary responsibility for the catabolism of TSA.	1.97606e-113
NZ_CP041168.1|WP_141207607.1|7253492_7255079_+|AMP-binding-protein	gnl|CDD|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	0
NZ_CP041168.1|WP_141207614.1|7261869_7262265_+|hydroxyisourate-hydrolase	gnl|CDD|376352	pfam00576, Transthyretin, HIUase/Transthyretin family. This family includes transthyretin that is a thyroid hormone-binding protein that transports thyroxine from the bloodstream to the brain. However, most of the sequences listed in this family do not bind thyroid hormones. They are actually enzymes of the purine catabolism that catalyze the conversion of 5-hydroxyisourate (HIU) to OHCU. HIU hydrolysis is the original function of the family and is conserved from bacteria to mammals; transthyretins arose by gene duplications in the vertebrate lineage. HIUases are distinguished in the alignment from the conserved C-terminal YRGS sequence.	6.3199e-47
NZ_CP041168.1|WP_141207605.1|7250834_7251665_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	8.59681e-14
NZ_CP041168.1|WP_020133468.1|7246867_7247659_-|serine-protease	gnl|CDD|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	6.43244e-75
NZ_CP041168.1|WP_141207612.1|7260900_7261260_+|transcriptional-regulator	gnl|CDD|379117	pfam13309, HTH_22, HTH domain. This domain is a helix-turn-helix domain that is likely to act as a DNA-binding domain.	7.8405e-22
NZ_CP041168.1|WP_141207609.1|7256346_7258131_+|glyoxylate-carboligase	gnl|CDD|183066	PRK11269, PRK11269, glyoxylate carboligase; Provisional.	0
NZ_CP041168.1|WP_141207608.1|7255339_7256152_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.0027113
NZ_CP041168.1|WP_062238673.1|7260652_7260904_+|hypothetical-protein	gnl|CDD|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	0.000430641
NZ_CP041168.1|WP_141207615.1|7262269_7263190_+|urate-oxidase	gnl|CDD|274554	TIGR03383, Structure_Of_Uricase, urate oxidase. Members of this protein family are urate oxidase, also called uricase. This protein contains two copies of the domain described by the uricase model pfam01014. In animals, this enzyme has been lost from primates and birds. [Central intermediary metabolism, Other].	1.90746e-150
NZ_CP041168.1|WP_141209512.1|7243067_7243613_+|kinase	gnl|CDD|235858	PRK06762, PRK06762, hypothetical protein; Provisional.	2.21558e-70
NZ_CP041168.1|WP_141207613.1|7261344_7261854_+|2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline-decarboxylase	gnl|CDD|184333	PRK13798, PRK13798, putative OHCU decarboxylase; Provisional.	1.93728e-69

Protein sequences

>NZ_CP041168.1|WP_141207607.1|7253492_7255079_+|AMP-binding-protein
MNSYTHGVSTTALLGDTIGANLDRAVATWPDREALVDVPSGRRWTYAQFGADVDELARALLGAGVVKGDRVGIWAVNCPEWTLVQYATARIGAIMVNINPAYRTHEVEYVLDQAGVCLLFASLSHKSSDYRAMVDEVRGRCRELREVVYIGDPSWRALLERAVEEPEFPELSCDDPINIQYTSGTTGFPKGATLSHHNILNNGYFVGELIAYGEQDRVCIPVPFYHCFGMVMGNLAATSHGACMVIPAPSFDPAATLSAVEQERCTSLYGVPTMFIAELNLPDFASYDLSSLRTGIMAGSPCPVEVMKRVVAEMHMAEVSICYGMTETSPVSLQTRRDDDLEHRTGTVGRVLPHIEVKVVDPATGVTQPRGTAGELCTRGYSVMLGYWNEPEKTAEAVDAGRWMHTGDLATMREDGYVEIVGRIKDMIIRGGENIYPREIEEFLYGHPKIADVQVVGVPHERYGEEVLACVIPRDPAIPPSLDELRAFCEDRLAHYKIPTRLRILETFPMTVSGKVRKVELREGYGEG
>NZ_CP041168.1|WP_141207606.1|7251781_7253449_+|AMP-binding-protein
MTATEDFRGARDFLLAHREDYATAYEGFVWPRPRHFNWALDWFDVIARGNDRTALHIVEEDGGEVRLSFAEMAERSDRVANLLRERGVEAEDRILVMLGNQTELWETALAAMKLRAVVIPATPLLGPADLRDRVERGRVRHVLVRAEDTGKFDDVPGDYTRIAVGGVPEGWQPYEDAHAASAEFLPDGPTLSDDPLMLYFTSGTTARPKLVEHTHTSYPIGHLATMYWIGLKPGDVHLNISSPGWAKHAWSNLFAPWNAEATVFIHNYTRFDAARLMAEMDRAGVTTFCAPPTVWRMLIQADLTQLRTPPREVVAAGEPLNPEVIEQVRRAWGVTIRDGFGQTETAVQVSNSPGQVLKAGSMGRPSPGYKVELLDPVSGAPGAAEGEIALDLSARPVGLMTGYHGDPDRTAEAMAGGYYRTGDVASRDEDGYLTYIGRSDDVFKASDYKISPFELESALLEHEAVAEAAVVPAPDELRLAVPKAYVVLAAGWEPGPDTAKVLFEHSRQTLAPYKRIRRLEFGALPKTVSGKIRRIELREATAAGSDAEYREEDFR
>NZ_CP041168.1|WP_141207605.1|7250834_7251665_-|helix-turn-helix-transcriptional-regulator
MTVDAAGAVEIRRALVRLRRTTGLPVAFGGLVEAGRPRMRISELSGTATTSLLALAVTSGNGLGGKTVALARPCAVADYSVSRQISHEYDAAVAAEGLRSVLAVPVVVRRRVRGVLYGALRDARPLGDRTMAAAVDAARDVEQALVVGDEARDVLAAARAEPPPGDTSGWEQVREAHAALRALAPRITDPALRTELLDACALLTPAPASPAGVALAPRELDVLACVAAGATNAVAAARLGVGAETVKAYLRSAMRKLGAGTRGEAVAAARRAGLLP
>NZ_CP041168.1|WP_141207604.1|7247874_7250691_-|AAA-family-ATPase
MTVPSDFQEPASCRPDLVIGRDDLFAQARDRLTRGGSVLLHGPAGIGKSTVLRALASECGDAARTVLRCSATESESHLPFLALADLFGLVLDDISDKLPAAQRTALESALTGRGESTLQRDGLALRLAVLSALRALAAEGPVLIVADDMQWLDPASLELLGFAARRLGDIPVRMLCAVRTDGPEYDHHLRVLPPDSLAVRFNPLTRAQTAALLDHRGYTGLQRSTVRDIHRTSGGNPFYALELGRALTESPVPPRPGDPLPVPTSLRALVLSRLEMLSEEARRTLLVASAGARPTPALLHAAGRGDAEAEMAQAAALGLLATEAEGPAVRFAHPLISAALYAEAPAQERREAHRALSTAASDPIERARHLALSTHGTDPEVATRLAEAAALARDRGAPSMAASLGLLSARHTPADSVPAPDVRRLTAAEDAITAGELDLARDIARDVLTRATVPADRVRAWIIVIDTAGHAMTEVDAVFPQALADAGDDPGLLALIRYQLAWRALLVEGDFDEARAEAARSAALAERAGDRYNELMGLSLQAQLETLMGHPDAPATIKRALKEPQDPRVSCHHNGAGYSRFRWLIMSDQLPEARATVTALLREVRRRGSVESEVHFLRGVAETELRSGHCGRALDLARESLMMARDTGIGEVASAVLASLAEASGGNVERALELAREAVGHSEENGDQMYESRGLAALGYAQLVAGDAEGAVRSLRRVRELEHGLGITDPARGRWQGDLAEALVRIGEIGEAQDVIDGTRVNALRLGRESVLAVLDRAEALVRAARGEHDAALDRLTSVQDRLAKLGYGLEEARAAFALAQLRTRQPGPTSYDEAARLFRRCRALPWLRQVETAALTRPVEPAAPLTTAQDGLDSLEGLASMERQVAALVMEGATNREIAARLFISVKTVEATLTRVYRKLGIRSRVDIVRLAAGRRS
>NZ_CP041168.1|WP_020133468.1|7246867_7247659_-|serine-protease
MFGLTRAKKAGAVGLATAAAAATALLSAPTAVAAPQPIVGGTTTTTTAYPFMMQITDASQNQFCGGTLVSATKVVTAAHCMVGETTSSVRVVGGRTYLNGTNGTVSRVSKIWINPSYTDATNGDDVAVLTLSTSMPYTKASYVSSSQTSVYAAGTTARILGWGTTSSNGSSSNQLRTATVPIVSDSSCKSSYGSDFVQSDMVCAGYTSGGTDTCQGDSGGPLLIGGVLAGITSWGEGCAQAGYPGVYTRLTTFSSLVTAQVNS
>NZ_CP041168.1|WP_141207603.1|7245001_7246231_+|winged-helix-DNA-binding-domain-containing-protein
MTKTTASAPVLGPRALNRATLDRQLLLRRSGMSAKAAVGHLLGLQAQNVKPPYYALAARLVGFAPEELSALMADREVVRIVTMRSTIHTHTAEDCRTLRPLVQPARDRELTHFRKGLQGVDLDRLAALARDLVESEPRTMKELREALLVEWPDADPQALAVAARCKLPLVQVTPRGLWGRSGQVALTTAEHWLGRPADTAPPSEHRPTEAAPPSERRPTEAAPSSEHRPTDPACPTPAPAPDATVLRYLAAFGPASVKDMQTWAGLTRLREAFERLRPELRVFRDEQGVELFDLPDAPRPAEDTPAPPRFLPEFDNLLLSHADRTRVVPKEYWGRNWQGNQAYCTLLVDGFLAGVWKLHGDTLVVEPFGRLTRAQREEVTEEAQRMLATLYPGTSYDIRFGTVVQQRAT
>NZ_CP041168.1|WP_141207602.1|7243692_7244853_-|magnesium-and-cobalt-transport-protein-CorA
MSERRPRPAGKNSARKSAWRRALTPPSAPPKSPAPAAEPTAPEPAEPPSIVQAALYRDGVRVSSPATLADTFRELREQPSGMAWIGLARPPESELLSLAEEFDLHPLSVEDAMEAHQRPKLERYGDTLFVVLRAARYLDAPEEVDFGELHVFVGPDFVITVRHGAAPDLSAVRHRMEQTPELLGLGPEAVLYAILDAVVDGYAPVVSGVQNDIDEIETEVFRGDPEVSRRIYELSREMVEFQRATRPLVGMLHALMAGFAKYGTDEELQRYLRDVADHVTHTSERVDGFRQALTDILTVNATLVTQQQNAEMRALAEAGFEQNEEIKKISSWAAILFAPTLVGTIYGMNFRHMPELHWGFGYPFAIALMGIVCTSLYVIFKRRDWL
>NZ_CP041168.1|WP_141209512.1|7243067_7243613_+|kinase
MTDVMVGTEETRLVVLRGNSASGKSSVAAGLRERFGRGLAVVGQDNLRRIVLRERDRPGAANIGLIDLTARYALDAGFHVVVEGLLYADHYGDMLTELRADHRGPTHAYYLDVPFGETLARHATKPIAHDVGETQLRDWYRPRDLLPGGIETVVGADSALQETVDRIMLDTGLAHLPAVDR
>NZ_CP041168.1|WP_141207601.1|7241068_7242595_-|hypothetical-protein
MHKPRTHALVSALSTVIAATLLATGCSTHSPATTDAAATSPVETPEPGTGQEKLAVVSAPTGDVATPTAVAAVNAVEPGKAKKTALKVASYDRKSGRAVIAAPRSGSDAAPSTPLPTTTTASPESSDSPGSSESSSGSGAPQGTGSSPATRPKAAVAVGDVIASAPVPGAPDGVLAKVTEIVDTTADGETTVRTEPTKLNSVLGRSEADGTVPVDPSTLDVDPLVKGVKVSWAKTGDLTFGPEGAKLPLGSLRIDVGAALQTAPGAPASAAASVQGFVQLAPQVSFSYDGSGSRANSSPSGAFLGLTGEWASQWRLKGRAAGTTRGKPIRVPFAELHAAPVIQVGPVPVVVNLDLVCYFQVDADGRVTVDAEQKLTGDFRVGGDFTWSKGWTGVSESHMSGEPLRTTVSAVGDVKAAMGAEATVGLYGTVGVTADLAPYLRADAEATGAGSADGTGSASGSWALYGGVDLNGTLNLQLSVFGTPVFRTRIPLGSLHKEWLLTKGTART
>NZ_CP041168.1|WP_141207600.1|7240485_7240974_+|hypothetical-protein
MDYGAVDAEIRRLVSAASEGEVRAFGQQTVIRLARSDRFQDADEDELTEQAWAALTTACANVLTLDAAELRAAVETIDDGILADGDLDTEVLVAIQALGHWQGYLEHGGREEIYELALRSIEDVDHEVCAALDDFLATPEMAAEYERIRRLLGSASDRRGQA
>NZ_CP041168.1|WP_141207608.1|7255339_7256152_-|hypothetical-protein
MSESVPVRCPACRREHLYAAPTYPCVCGAPVSPPLGPGARAVTHQVWEEAWVTVECALCGRRSEWPHPELGCACGTVLRIAVTADGADPARSVPERAAAGDGTARAVDPADASAAAEPPLPAGNAVPATPAPPAPPRRAFQPITIRTARDAVTVAALYLRWLGYQDIRRADQRPPSGIGLAARGTSGVGLTARGLLAQVDPTVRPASPRDVECLWLTAMTESAHCVYFSLAGYTAEARARADTLGVPLFVLDLTGTPQPVNTLADELGHT
>NZ_CP041168.1|WP_141207609.1|7256346_7258131_+|glyoxylate-carboligase
MARMTAARAAVEILKREGVTDAFGVPGAAINPFYAALKASGGIHHTLARHVEGASHMAEGYTRTHPGNIGVCIGTSGPAGTDMITGLYSATGDSIPILCITGQAPTAVIHKEDFQAVDIASIAGPVTKMAVTVLEAAQVPGVFQQAFHLMRSGRPGPVLIDLPIDVQLTEIEFDPETYEPLPVYKPAASRAQIEKAIGMLNASERPLIVAGGGVINADAAELLVEFAELTGTPVVPTLMGWGVLPDDHELNAGMVGLQTSHRYGNATFLESDFVLGIGNRWANRHTGKLDVYTAGRTFVHVDVEPTQIGRIFAPDYGIASDAKAALTLFVEVARELKAAGRLPDRGAWAASAQEKKATLQRRTHFDDIPIKPQRVYEEMNKAFGPETRYVSTIGLSQIAGAQMLHVFRPRHWINCGQAGPLGWTVPAALGVAKADPEAQVVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNSYLGLIRQAQRAFDIDFQVNLEFENVNSPELGVYGVDHVKVAEGLGCKAIRVTDPAELGAALEQAKKLAAEFQVPVVVEAILERVTNIAMSTTNDIGNVVEFEELATEPGHAPTSIRTLKV
>NZ_CP041168.1|WP_141207610.1|7258771_7259662_-|2-hydroxy-3-oxopropionate-reductase
MSSLPKIAWIGLGIMGSPMSENLVKAGYDVTGYTLEQDKLDRLAAAGGTAAASIAEAVRDADVIITMVPASPQVEAIAYGPDGILANARSGALLIDMSSITPQTSVDLAKAAAEKGIRVLDAPVSGGEAGAIEAVLSIMVGGEQADFDEAEPVFEALGKTIVLCGPHGSGQTVKAANQLIVAVNIQACAEAVVFLEKSGVNLKAALDVLNGGLAGSTVLTRKKDNFLQRDFKPGFRIDLHHKDMGIVTDAARTVGAALPVGAVVAQLVASLRAQGDGGLDHSALLRAVERLSGAQV
>NZ_CP041168.1|WP_141207611.1|7259693_7260515_-|TIM-barrel-protein
MGFAEQRFNVNLSILFTELPLLERPAAAAAAGFTAVELWWPWIDTPTPEQSELDALKRAVEDAGVQLTGLNFYAGELPGPDRGALSIPGEESERFRANIDVAADFAGSLGATALNALYGNRVDGVDPAEQDALALENLVLAARAADRIGAVLLIEALNRPESPRYPLVSAPAAVGIVDKVNAASGLGNARFLMDLYHLSMNGEDLPAVIEEFTPKTGHVQIADNPGRGAPGTGTLPLEELLGLLAKAGYDGWVGLEYKPGDRPSAEAFDWLAR
>NZ_CP041168.1|WP_062238673.1|7260652_7260904_+|hypothetical-protein
MRLRVEFTTEPFDLDEAPAHALVAREVIEAAELDAVDVGPFGNTAEGGADQVLGAVDALLHRALAAGATRISLQVNVVAEGDV
>NZ_CP041168.1|WP_141207612.1|7260900_7261260_+|transcriptional-regulator
MSADEPFIAAVKPLVDAMGGELLPPDEAGPDDVVLAWEGADVVAVRLPQLADSLDHILAAMERKRGVPLADLDRKAKQEVVRVLEARGAFSVRHGVETVASALGVSRFTVYNYLNRDKA
>NZ_CP041168.1|WP_141207613.1|7261344_7261854_+|2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline-decarboxylase
MTSTSTPPGLARFNALEESAARAVLLEACASTAWARRLLAARPYATADDLYAQSDAAMAELTAEDLGEAMGGHPPIGRPKPGDPASAREQSGMASAGDALKAEMLELNLAYQERFGHVFLICATGRSAEEMRDAVKERIGNAPEQEREIVRTELGRINRIRLARIVAED
>NZ_CP041168.1|WP_141207614.1|7261869_7262265_+|hydroxyisourate-hydrolase
MSSSTTASVSTHILDTSVGRPAEGVAVRLAARGGRDAAWQALGGSATDADGRCKDLPALPEGTSHVRLDFEVEPYFLKKQADAQQDAPANRDSGAGVFFPEVAITFAVEPGEHYHVPLLLNPFGYSVYRGS
>NZ_CP041168.1|WP_141207615.1|7262269_7263190_+|urate-oxidase
MTDNSRPARPVILGQNQYGKAENRVVRITRDGATHHIKDLNVSVSLSGAMDDVHYSGSNASVLPTDTTKNTVYAFAKEHGIESAEQFGIHLARHFVTSQEPIHRARIRIEEYTWERIEVPGEARHSFVRKGQETRLAQITYDGSSWEVVSGLKDLTVLNSTDSEFWGYVKDKYTTLPEAYDRILATDVSGRWRFNWTDDAQEMPDWDTSYEQTKQHMLRAFAETYSLSLQQTLYQMGSRIIENRDEIDEVRFSLPNKHHFLVDLEPFGLKNDNEVYFAADRPYGLIEATVLRDGREARIPADLTTL
>NZ_CP041168.1|WP_141207616.1|7263200_7264580_+|8-oxoguanine-deaminase
MTALQRIVIENCSIATVDADDTEYASGHVVIAGNRIESLGAGPAPQGLQDVVRRIDATGHLVTPGLVNTHHHYYQWITRGLATDHNLFNWLVALYPTWARIDEEMVYAAAQGSLAMMARGGVTTAMDHHYVFPKDSGDLSGAIIRAACETGVRFTLARGSMDRSEKDGGLPPDFAVETLEGALTATEATVKEHHDSSFDAMTQVAVAPCSPFSVSTELLREGAELARRLGVRLHTHGSETVEEEQFCKELFGMGPTDYFESTGWLGEDVWMAHCVHMNDSDIAAFARTKTGVAHCPSSNARLAAGIARVPDMLAAGVPVGLGVDGTASNESGELHTELRNALLINRLGAHREAALNARQALRLGTYGGAQVLGRAAETGSLEAGKLADLVLWKLDTLAHASIADPVTALVFGAAAPVTASFVNGRQIVEDSRLLHVDEDAVARSTREQARRLARIAAQG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP041168.1	5869082-5869106	1	0.96
NZ_CP041168_5	5.1|4220838|19|NZ_CP041168|CRISPRCasFinder	4220838-4220856	19	NZ_CP041168.1	5002739-5002757	2	0.895
NZ_CP041168_8	8.1|6070362|20|NZ_CP041168|CRISPRCasFinder	6070362-6070381	20	NZ_CP041168.1	236044-236063	2	0.9
NZ_CP041168_8	8.1|6070362|20|NZ_CP041168|CRISPRCasFinder	6070362-6070381	20	NZ_CP041168.1	1216745-1216764	2	0.9
NZ_CP041168_8	8.1|6070362|20|NZ_CP041168|CRISPRCasFinder	6070362-6070381	20	NZ_CP041168.1	2781774-2781793	2	0.9
NZ_CP041168_8	8.1|6070362|20|NZ_CP041168|CRISPRCasFinder	6070362-6070381	20	NZ_CP041168.1	3456637-3456656	2	0.9
NZ_CP041168_8	8.1|6070362|20|NZ_CP041168|CRISPRCasFinder	6070362-6070381	20	NZ_CP041168.1	6811037-6811056	2	0.9
NZ_CP041168_11	11.1|6492748|19|NZ_CP041168|CRISPRCasFinder	6492748-6492766	19	NZ_CP041168.1	665604-665622	2	0.895

1. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to position: 5869082-5869106, mismatch: 1, identity: 0.96

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ctcctgggcggcggtcagcgtctcg	Protospacer
**************.**********

2. spacer 5.1|4220838|19|NZ_CP041168|CRISPRCasFinder matches to position: 5002739-5002757, mismatch: 2, identity: 0.895

acctcaggtctcagctcag	CRISPR spacer
acctcaggactcagcccag	Protospacer
******** ******.***

3. spacer 8.1|6070362|20|NZ_CP041168|CRISPRCasFinder matches to position: 236044-236063, mismatch: 2, identity: 0.9

cggactggcccccgccgccg	CRISPR spacer
cggactggacccggccgccg	Protospacer
******** *** *******

4. spacer 8.1|6070362|20|NZ_CP041168|CRISPRCasFinder matches to position: 1216745-1216764, mismatch: 2, identity: 0.9

cggactggcccccgccgccg	CRISPR spacer
cggcctgtcccccgccgccg	Protospacer
*** *** ************

5. spacer 8.1|6070362|20|NZ_CP041168|CRISPRCasFinder matches to position: 2781774-2781793, mismatch: 2, identity: 0.9

cggactggcccccgccgccg	CRISPR spacer
cggactggcccccggccccg	Protospacer
************** * ***

6. spacer 8.1|6070362|20|NZ_CP041168|CRISPRCasFinder matches to position: 3456637-3456656, mismatch: 2, identity: 0.9

cggactggcccccgccgccg	CRISPR spacer
cggacaggccccggccgccg	Protospacer
***** ****** *******

7. spacer 8.1|6070362|20|NZ_CP041168|CRISPRCasFinder matches to position: 6811037-6811056, mismatch: 2, identity: 0.9

cggactggcccccgccgccg	CRISPR spacer
cggactggccccggccgacg	Protospacer
************ **** **

8. spacer 11.1|6492748|19|NZ_CP041168|CRISPRCasFinder matches to position: 665604-665622, mismatch: 2, identity: 0.895

cgtgccctgcgcgccgttg	CRISPR spacer
cgtgccctgcccgctgttg	Protospacer
********** ***.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	162026-162050	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP024312	Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence	62555-62579	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	2503508-2503532	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MH588544	Caulobacter phage CcrBL10, complete genome	62702-62726	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1300493-1300517	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1589818-1589842	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MF975638	Streptomyces phage Abt2graduatex2, complete genome	10335-10359	3	0.88
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	77861-77885	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	473537-473561	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	874470-874494	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NC_023316	Streptomyces sp. 14R-10 plasmid pZL1, complete sequence	122367-122391	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1519865-1519889	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	788576-788600	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	97153-97177	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	CP054917	Streptomyces sp. NA02950 plasmid unnamed, complete sequence	100470-100494	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	84531-84555	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	946584-946608	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	965436-965460	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1142062-1142086	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1295026-1295050	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	863620-863644	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	950932-950956	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	443348-443372	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	670376-670400	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	878035-878059	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	778940-778964	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	876638-876662	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	875142-875166	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	950921-950945	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	944720-944744	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	987659-987683	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	965474-965498	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	841274-841298	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	944720-944744	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	987659-987683	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	181237-181261	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP054033	Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence	572855-572879	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	944720-944744	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	841297-841321	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	944724-944748	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	987659-987683	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	987659-987683	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	987659-987683	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	841297-841321	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	878311-878335	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	858999-859023	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	906071-906095	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	953087-953111	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	841297-841321	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	944720-944744	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	841297-841321	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	841297-841321	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	987661-987685	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MK224497	Mycobacterium phage Henu3, complete genome	53956-53980	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1767300-1767324	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1327339-1327363	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP042265	Litoreibacter sp. LN3S51 plasmid unnamed4, complete sequence	174269-174293	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	321862-321886	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	9235-9259	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	746484-746508	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	97359-97383	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1151989-1152013	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052758	Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence	118519-118543	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	930136-930160	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1747473-1747497	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	161666-161690	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1293232-1293256	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	209580-209604	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1112655-1112679	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1293199-1293223	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1292004-1292028	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	1371672-1371696	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1292041-1292065	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1292041-1292065	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	493999-494023	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1088469-1088493	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1292030-1292054	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1197508-1197532	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1292030-1292054	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1016785-1016809	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1293197-1293221	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1292041-1292065	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1115469-1115493	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1292052-1292076	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1292030-1292054	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1115469-1115493	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MN369761	Mycobacterium phage Malthus, complete genome	5019-5043	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	KJ944841	Mycobacterium phage Cheetobro, complete genome	5029-5053	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	AP018469	Mycobacterium phage Y10 DNA, complete genome, note: sample1	5019-5043	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	KY087992	Mycobacterium phage Mitti, complete genome	5032-5056	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MF140402	Mycobacterium phage Chancellor, complete genome	5029-5053	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	AP018470	Mycobacterium phage Y2 DNA, complete genome	5019-5043	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	KT361920	Mycobacterium phage Slarp, complete genome	5029-5053	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MT310882	Mycobacterium phage JF1, complete genome	5019-5043	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	AP018471	Mycobacterium phage Y10 DNA, complete genome, note: sample2	5019-5043	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	KX621007	Mycobacterium phage Taquito, complete genome	4630-4654	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MH051258	Mycobacterium phage SamScheppers, complete genome	4629-4653	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	MF140435	Mycobacterium phage Wintermute, complete genome	5018-5042	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NC_027365	Mycobacterium virus Fionnbarth, complete genome	5019-5043	4	0.84
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	118900-118924	5	0.8
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	483499-483523	5	0.8
NZ_CP041168_6	6.2|5257900|29|NZ_CP041168|CRISPRCasFinder	5257900-5257928	29	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	140821-140849	6	0.793
NZ_CP041168_6	6.2|5257900|29|NZ_CP041168|CRISPRCasFinder	5257900-5257928	29	MK376961	Gordonia phage Asapag, complete genome	42725-42753	6	0.793
NZ_CP041168_6	6.2|5257900|29|NZ_CP041168|CRISPRCasFinder	5257900-5257928	29	NZ_CP010659	Phaeobacter piscinae strain P71 plasmid pP71_c, complete sequence	37930-37958	6	0.793
NZ_CP041168_6	6.2|5257900|29|NZ_CP041168|CRISPRCasFinder	5257900-5257928	29	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	113779-113807	6	0.793
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	593565-593589	6	0.76
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NC_015409	Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence	11130-11154	6	0.76
NZ_CP041168_10	10.1|6282611|25|NZ_CP041168|CRISPRCasFinder	6282611-6282635	25	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	134634-134658	6	0.76
NZ_CP041168_6	6.2|5257900|29|NZ_CP041168|CRISPRCasFinder	5257900-5257928	29	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	466815-466843	7	0.759
NZ_CP041168_6	6.2|5257900|29|NZ_CP041168|CRISPRCasFinder	5257900-5257928	29	NZ_CP048426	Rhizobium daejeonense strain KACC 13094 plasmid unnamed3, complete sequence	4973-5001	7	0.759
NZ_CP041168_8	8.2|6070407|32|NZ_CP041168|CRISPRCasFinder	6070407-6070438	32	NZ_CP015585	Roseomonas gilardii strain U14-5 plasmid 1, complete sequence	78141-78172	7	0.781
NZ_CP041168_2	2.1|1593060|30|NZ_CP041168|CRISPRCasFinder	1593060-1593089	30	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	135255-135284	8	0.733
NZ_CP041168_8	8.2|6070407|32|NZ_CP041168|CRISPRCasFinder	6070407-6070438	32	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	605780-605811	8	0.75
NZ_CP041168_10	10.4|6282830|37|NZ_CP041168|CRISPRCasFinder	6282830-6282866	37	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	272106-272142	10	0.73

1. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtcctgggcggcggccagcgtcccc	Protospacer
 *********************.* 

2. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP024312 (Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ttccttgacggcggccagcgtctcg	Protospacer
.**** *.*****************

3. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ttcctggccggcgggcagcgtctcg	Protospacer
.****** ****** **********

4. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MH588544 (Caulobacter phage CcrBL10, complete genome) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
cttctgggcggcggccagcgcctcc	Protospacer
**.*****************.*** 

5. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
cgccttggcggcggccagcgtcacg	Protospacer
* *** **************** **

6. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
cgccttggcggcggccagcgtcacg	Protospacer
* *** **************** **

7. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MF975638 (Streptomyces phage Abt2graduatex2, complete genome) position: , mismatch: 3, identity: 0.88

ctcctgggcggcggccagcgtctcg	CRISPR spacer
cgcctgcgcggcggccagcgtcccg	Protospacer
* **** ***************.**

8. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcgagggcggcggccagcgtctcg	Protospacer
  *  ********************

9. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctgggcggcggccagcgactcc	Protospacer
  ****************** *** 

10. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

11. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NC_023316 (Streptomyces sp. 14R-10 plasmid pZL1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gacccgggcggcggccagcgtcgcg	Protospacer
  **.***************** **

12. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

13. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

14. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gccctgggcggcggtcagcgcctcg	Protospacer
 .************.*****.****

15. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to CP054917 (Streptomyces sp. NA02950 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctgggccgcggccagggtctcg	Protospacer
  ******* ******** ******

16. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gccctgggcggcggtcagcgcctcg	Protospacer
 .************.*****.****

17. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

18. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

19. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

20. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

21. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

22. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

23. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gccctgggcggcggtcagcgcctcg	Protospacer
 .************.*****.****

24. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

25. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

26. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

27. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

28. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

29. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

30. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

31. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

32. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

33. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

34. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

35. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

36. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcgtggtcggcggccagcgtctcg	Protospacer
  * *** *****************

37. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP054033 (Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gccctgggcggcggtcagcgcctcg	Protospacer
 .************.*****.****

38. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

39. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

40. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

41. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

42. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

43. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

44. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

45. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

46. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

47. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

48. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

49. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

50. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

51. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

52. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

53. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

54. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MK224497 (Mycobacterium phage Henu3, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

55. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

56. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

57. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP042265 (Litoreibacter sp. LN3S51 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctgcgcggcggccagcgtgtcg	Protospacer
  **** ************** ***

58. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ctccagggcggcggccagcggctga	Protospacer
**** *************** ** .

59. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
atcctgcgcgccggccagcgtctcc	Protospacer
 ***** *** ************* 

60. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
atcctgcgcgccggccagcgtctcc	Protospacer
 ***** *** ************* 

61. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gaccagggcgacggccagcgtctcg	Protospacer
  ** *****.**************

62. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

63. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052758 (Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gacctgggcgtcggccagcctctcg	Protospacer
  ******** ******** *****

64. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

65. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

66. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
atccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

67. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

68. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

69. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

70. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

71. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

72. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctgggtggcggccagggtctcg	Protospacer
  ******.********* ******

73. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

74. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

75. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ctccagggcggcggccagcggctga	Protospacer
**** *************** ** .

76. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

77. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

78. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

79. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

80. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

81. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

82. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

83. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

84. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

85. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

86. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gtccggcgcggcggccagcgtctcc	Protospacer
 *** * ***************** 

87. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MN369761 (Mycobacterium phage Malthus, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

88. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to KJ944841 (Mycobacterium phage Cheetobro, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

89. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to AP018469 (Mycobacterium phage Y10 DNA, complete genome, note: sample1) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

90. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to KY087992 (Mycobacterium phage Mitti, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

91. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MF140402 (Mycobacterium phage Chancellor, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

92. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to AP018470 (Mycobacterium phage Y2 DNA, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

93. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to KT361920 (Mycobacterium phage Slarp, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

94. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MT310882 (Mycobacterium phage JF1, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

95. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to AP018471 (Mycobacterium phage Y10 DNA, complete genome, note: sample2) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

96. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to KX621007 (Mycobacterium phage Taquito, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

97. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MH051258 (Mycobacterium phage SamScheppers, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

98. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to MF140435 (Mycobacterium phage Wintermute, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

99. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NC_027365 (Mycobacterium virus Fionnbarth, complete genome) position: , mismatch: 4, identity: 0.84

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ggcctcggcggcggccagcgcctcg	Protospacer
  *** **************.****

100. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.8

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gggatcggcggcggccagcgtctcg	Protospacer
    * *******************

101. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 5, identity: 0.8

ctcctgggcggcggccagcgtctcg	CRISPR spacer
gaggtcggcggcggccagcgtctcg	Protospacer
    * *******************

102. spacer 6.2|5257900|29|NZ_CP041168|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 6, identity: 0.793

accggcatgccccaccggaccggcgtgcc	CRISPR spacer
ggcggcatgccccaccggaccggcgccgg	Protospacer
. ***********************.   

103. spacer 6.2|5257900|29|NZ_CP041168|CRISPRCasFinder matches to MK376961 (Gordonia phage Asapag, complete genome) position: , mismatch: 6, identity: 0.793

accggcatgccccaccggaccggcgtgcc	CRISPR spacer
tccggcatgcgccaccggaacggcgcctc	Protospacer
 ********* ******** *****. .*

104. spacer 6.2|5257900|29|NZ_CP041168|CRISPRCasFinder matches to NZ_CP010659 (Phaeobacter piscinae strain P71 plasmid pP71_c, complete sequence) position: , mismatch: 6, identity: 0.793

accggcatgccccaccggaccggcgtgcc	CRISPR spacer
atccacatgccccacctgaccggcgagca	Protospacer
*.* .*********** ******** ** 

105. spacer 6.2|5257900|29|NZ_CP041168|CRISPRCasFinder matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 6, identity: 0.793

accggcatgccccaccggaccggcgtgcc	CRISPR spacer
gtcggcatgcccgacaggaccggcgcggc	Protospacer
..********** ** *********.* *

106. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.76

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ttcctgggcggcggccagcgcgaac	Protospacer
.*******************.    

107. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NC_015409 (Verrucosispora maris AB-18-032 plasmid pVMKU, complete sequence) position: , mismatch: 6, identity: 0.76

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ctcctgggcggcggccagcagggta	Protospacer
*******************.   ..

108. spacer 10.1|6282611|25|NZ_CP041168|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 6, identity: 0.76

ctcctgggcggcggccagcgtctcg	CRISPR spacer
ttcctgggcggcggccagcgcgaac	Protospacer
.*******************.    

109. spacer 6.2|5257900|29|NZ_CP041168|CRISPRCasFinder matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 7, identity: 0.759

accggcatgccccaccggaccggcgtgcc	CRISPR spacer
gccggcctgccacaccggaccggctgaca	Protospacer
.***** **** ************  .* 

110. spacer 6.2|5257900|29|NZ_CP041168|CRISPRCasFinder matches to NZ_CP048426 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

accggcatgccccaccggaccggcgtgcc	CRISPR spacer
accggcatgcaccaccggacccatcgggc	Protospacer
********** ********** ..  * *

111. spacer 8.2|6070407|32|NZ_CP041168|CRISPRCasFinder matches to NZ_CP015585 (Roseomonas gilardii strain U14-5 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.781

acgaggcgccttacgacgacgaggcgccctac	CRISPR spacer
gcggcgcgccttacgacgaggacgcgcccacc	Protospacer
.**. ************** ** ******  *

112. spacer 2.1|1593060|30|NZ_CP041168|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.733

tgcgggccacccttccacgcgcgggtgcga	CRISPR spacer
agcgggccacccgtccgcgcgcggcgaagg	Protospacer
 *********** ***.*******  . *.

113. spacer 8.2|6070407|32|NZ_CP041168|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 8, identity: 0.75

acgaggcgccttacgacgacgaggcgccctac	CRISPR spacer
acgaggcgcctttcgaccacgagggtgagttc	Protospacer
************ **** ******     * *

114. spacer 10.4|6282830|37|NZ_CP041168|CRISPRCasFinder matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.73

ggcctcggcctgctgctggagggtgcggatccgctcg---	CRISPR spacer
accctctgcctgctgctggggggtgcggg---ggccgagc	Protospacer
. **** ************.********.   * .**