CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP041194	Weissella cibaria strain CBA3612 plasmid pCBA3612-01, complete sequence	0 crisprs	csa3	0	0
NZ_CP041193	Weissella cibaria strain CBA3612 chromosome, complete genome	2 crisprs	csa3,csn2,cas2,cas1,cas9,cas3,DEDDh,csa5gr11	2	4
NZ_CP041196	Weissella cibaria strain CBA3612 plasmid pCBA3612-03, complete sequence	0 crisprs	NA	0	0
NZ_CP041195	Weissella cibaria strain CBA3612 plasmid pCBA3612-02, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041193_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041193_1

395796-396031

TypeII

Consensus_repeat	Method
AAGTTTGAGAAGCATTCTATTCAACATGACACTAAAAC	CRT
ATTCTATTCAACATGACACTAAAAC	CRISPRCasFinder
AAGTTTGAGAAGCATTCTATTCAACATGACACTAAAAC	PILER-CR

3 spacers

csa3,csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP041193_1

>merge|NZ_CP041193|1|395796-396031|CRT,CRISPRCasFinder,PILER-CR
CAATTTGAAAAATATTCTATTCAACATGACACTAAAACCTGAAGCAATTCACTGGTGTTGATGCGGACGTTTGAGAAGCATTCTATTCAACATGACACTAAAACTAAAACAACGCGTGTTTATTGGTTCCATAAGTTTGAGAAGCATTCTATTCAACATGACACTAAAACAATCAAGAACGTTCAATCAATCATCAACAAGTTTGAGAAGCATTCTATTCAACATGACACTAAAAC

>NZ_CP041193|1|1|395796-396031|CRT
CAATTTGAAAAATATTCTATTCAACATGACACTAAAAC	CTGAAGCAATTCACTGGTGTTGATGCGG
ACGTTTGAGAAGCATTCTATTCAACATGACACTAAAAC	TAAAACAACGCGTGTTTATTGGTTCCAT
AAGTTTGAGAAGCATTCTATTCAACATGACACTAAAAC	AATCAAGAACGTTCAATCAATCATCAAC
AAGTTTGAGAAGCATTCTATTCAACATGACACTAAAAC

>NZ_CP041193|1|1|395809-396031|CRISPRCasFinder
ATTCTATTCAACATGACACTAAAAC	CTGAAGCAATTCACTGGTGTTGATGCGGACGTTTGAGAAGC
ATTCTATTCAACATGACACTAAAAC	TAAAACAACGCGTGTTTATTGGTTCCATAAGTTTGAGAAGC
ATTCTATTCAACATGACACTAAAAC	AATCAAGAACGTTCAATCAATCATCAACAAGTTTGAGAAGC
ATTCTATTCAACATGACACTAAAAC

>NZ_CP041193|1|1|395864-396031|PILER-CR
GTTTGAGAAGCATTCTATTCAACATGACACTAAAACTA	AAACAACGCGTGTTTATTGGTTCCATAA
GTTTGAGAAGCATTCTATTCAACATGACACTAAAACAA	TCAAGAACGTTCAATCAATCATCAACAA
GTTTGAGAAGCATTCTATTCAACATGACACTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041193.1\|WP_010373838.1\|394074_394677_-\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NZ_CP041193.1\|WP_010373835.1\|393231_394047_-\|NAD-kinase	unknown	unknown	gnl\|CDD\|235317
NZ_CP041193.1\|WP_141146502.1\|399495_402735_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP041193.1\|WP_141146501.1\|398261_399458_-\|hypothetical-protein	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374655
NZ_CP041193.1\|WP_063084249.1\|388169_388577_-\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	unknown	unknown	gnl\|CDD\|226180
NZ_CP041193.1\|WP_063084250.1\|394964_395576_+\|dithiol-disulfide-isomerase	unknown	unknown	gnl\|CDD\|372699
NZ_CP041193.1\|WP_063084261.1\|389841_390369_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP041193.1\|WP_010373846.1\|404066_404912_-\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
NZ_CP041193.1\|WP_108730631.1\|403451_404048_-\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP041193.1\|WP_063084258.1\|405755_406067_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_063084257.1\|405071_405692_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|372595
NZ_CP041193.1\|WP_063084252.1\|396845_397181_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP041193.1\|WP_081215792.1\|396181_396859_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP041193.1\|WP_010373833.1\|392320_393232_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP041193.1\|WP_141146499.1\|387174_388068_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_CP041193.1\|WP_010373842.1\|402929_403448_-\|YfcE-family-phosphodiesterase	unknown	unknown	gnl\|CDD\|223695
NZ_CP041193.1\|WP_010373795.1\|386850_387159_-\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP041193.1\|WP_010373802.1\|388644_389805_-\|DUF2075-domain-containing-protein	unknown	unknown	gnl\|CDD\|378274
NZ_CP041193.1\|WP_141146500.1\|397177_398050_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP041193.1\|WP_141146880.1\|390909_392262_-\|magnesium-transporter	unknown	unknown	gnl\|CDD\|225148

Protein	Function_ID	Function_description	E-value
NZ_CP041193.1\|WP_010373838.1\|394074_394677_-\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	1.4962e-68
NZ_CP041193.1\|WP_010373835.1\|393231_394047_-\|NAD-kinase	gnl\|CDD\|235317	PRK04885, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	5.53057e-153
NZ_CP041193.1\|WP_141146502.1\|399495_402735_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	8.35788e-114
NZ_CP041193.1\|WP_141146501.1\|398261_399458_-\|hypothetical-protein	gnl\|CDD\|374655	pfam16595, Cas9_PI, PAM-interacting domain of CRISPR-associated endonuclease Cas9. Cas9_PI is a family found at the C-terminal of bacterial type II CRISPR system Cas9 endonuclease. This domain adopts a novel protein fold that is unique to the Cas9 family. It is positioned in the structure-DNA-complex to recognize the PAM sequence on the non-complementary DNA strand of the crRNA. PAM sequence is protospacer-adjacent motifs on DNA. See family CRISPR-DR2, Rfam:RF01315. Cas9 carries two nuclease domains, HNH and RuvC, which cleave the DNA strands that are complementary and non-complementary to the 20 nucleotide guide sequence in crRNAs, respectively.	1.04107e-10
NZ_CP041193.1\|WP_063084249.1\|388169_388577_-\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	gnl\|CDD\|226180	COG3654, Doc, Prophage maintenance system killer protein [General function prediction only].	5.56903e-13
NZ_CP041193.1\|WP_063084250.1\|394964_395576_+\|dithiol-disulfide-isomerase	gnl\|CDD\|372699	pfam13743, Thioredoxin_5, Thioredoxin.	5.15378e-33
NZ_CP041193.1\|WP_063084261.1\|389841_390369_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.79604e-18
NZ_CP041193.1\|WP_010373846.1\|404066_404912_-\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	5.35544e-108
NZ_CP041193.1\|WP_108730631.1\|403451_404048_-\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	4.02885e-96
NZ_CP041193.1\|WP_063084257.1\|405071_405692_-\|HAD-family-hydrolase	gnl\|CDD\|372595	pfam13419, HAD_2, Haloacid dehalogenase-like hydrolase.	1.54553e-47
NZ_CP041193.1\|WP_063084252.1\|396845_397181_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.45641e-38
NZ_CP041193.1\|WP_081215792.1\|396181_396859_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.74738e-70
NZ_CP041193.1\|WP_010373833.1\|392320_393232_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.26791e-86
NZ_CP041193.1\|WP_141146499.1\|387174_388068_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.46494e-69
NZ_CP041193.1\|WP_010373842.1\|402929_403448_-\|YfcE-family-phosphodiesterase	gnl\|CDD\|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	1.91713e-31
NZ_CP041193.1\|WP_010373795.1\|386850_387159_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.40285e-16
NZ_CP041193.1\|WP_010373802.1\|388644_389805_-\|DUF2075-domain-containing-protein	gnl\|CDD\|378274	pfam09848, DUF2075, Uncharacterized conserved protein (DUF2075). This domain, found in various prokaryotic proteins (including putative ATP/GTP binding proteins), has no known function.	3.2783e-118
NZ_CP041193.1\|WP_141146500.1\|397177_398050_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.63414e-111
NZ_CP041193.1\|WP_141146880.1\|390909_392262_-\|magnesium-transporter	gnl\|CDD\|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	1.2312e-127

>NZ_CP041193.1|WP_063084250.1|394964_395576_+|dithiol-disulfide-isomerase
MLEVYHFVNPLSGDSLETEKKLASYVTTATEKIALQVVPVMTMQSVHETAVALGHPDQEQVLSQTMYRFILDVKALQFQGKKVARRFLEAAQTAIFSGQPYTDEFVMGLVADIAADPTLFLEDRNSDLTIQAYRADHNMAAEMGVTQFPTLVVYNTNGANHASRTTDFSDESLRSLITPTANQQLNTYDDYLHNGHVTEIEEG
>NZ_CP041193.1|WP_010373838.1|394074_394677_-|GTP-pyrophosphokinase-family-protein
MTHNEWDKLLQPYVQAVDELKVKLRGMRTEFELAGIKTPVEFVTGRVKAIPAIEEKLVRRHIDMERLEQDMEDLAGVRIMTQFTEDIFKIVDLLRQRKDMVILEERDYVSNAKPSGYRSYHIVIEYPVQLITGEKKILAEIQVRTMQMNVWATIEHAINYKYDGDYTPEMTEKLREVAELSIRVDELFSELHNGLDKPTD
>NZ_CP041193.1|WP_010373835.1|393231_394047_-|NAD-kinase
MKLAIYSNNGAQSKAVVALFKEKLAARNTDKIVFDDEHPDVVISVGGDGTLLGAFHHYADQLAFVRFIGVHTGHLGFYADWQHFEIDELIDSLVNDEDARTVKYPLLEAHVRYTDGREERVLALNEAAIKRPLGTLVADVYIQGELFERFRGDGLTASTPTGSTAYNKAIGGAVMHPSLDAIQLAEIASINSRVFRTLGSPLIIGNHEVIRVQLENDGAAVTLSFDHLSKIASNIDWIEFRVSKTKIQFAEYRHMHFWHRVQSSFIGTEVK
>NZ_CP041193.1|WP_010373833.1|392320_393232_-|RluA-family-pseudouridine-synthase
MAQFSWINQGDETLKIKTFLAQRGVSHRMFSIVKRGGGAVLLAGKQVRTVDEVKPGDKVTIVMPPEESNDVVAMSDLPITVLYEDENWLVVEKEAGVTSVPGKADRETTMVNRVKGYLARSGAEDLVPHVVTRLDRFTSGVALLAKHRFAHGLLDKQLQTHSVDKRYYAIVDGDLPDDYGFIDAPIGRMDDDFIRREVREDGRPSQTEYWVVKRFGNQTLVRVQLHTGRTHQIRVHFKYLGHPLIGDEIYGGPMDRGITRQALHAYWLRFYDPFAQVERTTQSALPQDIVAVLDGYQVEPDEN
>NZ_CP041193.1|WP_141146880.1|390909_392262_-|magnesium-transporter
MRDELSEQAHHLVDYLEHGEKEAFLDGFDELHGYDKAVFYVTLPSQLRHQIIEWLTPTELAEVFDEIEPEDVDINDLLEEMSPRYAAQMLNQMYTDNSVDLFEDMDQRELGMYLALMPKEDAAQIRRLLNYEDDTAGSLMGTEFVAINQKLTIGQAMTAVKKAAQEAEQITYIYVVDDDEKLVGVISLRSLIVWPDEAKVADVMDTNLITVTPSDDQEDVARLMADYNFVSIPVVVKDHLVGTITVDDIVDVIDEEAAEDYSRLAGVDVVTLEENPFKSAAKRLPWLVGLIFLGMGTASVINNFEGLVSQASILAVFISLITGTAGNAGTQSLAVSVRRLALKETSSLIKMLMTEVLIGAMIGTTAGLTIFLVVWIWKANMLLGVAVGLAMGVAILVANVAGSFIPLVMDKIGVDPAVASGPFISTLSDLTSVIIYFNIAGLFISHFVSA
>NZ_CP041193.1|WP_063084261.1|389841_390369_-|GNAT-family-N-acetyltransferase
MSMTLRRLTTKDLDTLRDISIETFSDTFGAQNTAENMRDYLAAAYTPEKLAAELANPASMFYFVLVDEKIAGYLKLNVDDAQSEKMGEDALEVERIYVRRSFQRQGLGRVFIGEAERLAKSLDKHQIWLGVWEHNPNAIAFYEKMGFTLTGEAHDFYMGTDQQTDVLMMKNLASK
>NZ_CP041193.1|WP_010373802.1|388644_389805_-|DUF2075-domain-containing-protein
MNKILKEQFFVDNLSAEQEAVISNMNAYIGDGLKQNDHRVAIIQGAAGTGKSVVLMNLVTKYMTDKRYKTALVVNHPELFKAYKDLAVDIPGMRDKDITRPTPLINNAQKRNWQYDVIFVDEAHLLLSKPEPYMHYNGENQLADLMSLAKVVVVVYDFAQVFQSKMYWDKDLLFKTIGNNPYHQFDMDFQYRMVASQEQVDWLDDLTAEKPLKPFPYNSEFEFKVFDKAGDLYEAIKEKNKEFGQSRVVATSGFPRIDGRHNVEMDTFNLPWDEWDPQRTHWAKREGSITQVGTIYTLQGFDLNYVGMIIGPSFGYDPKTDSVTIIPEKYSHKEIFKKRQDRKFTEDEFKAFIANVLNVLIKRGKYGLYLTAYDDALRARLLELQK
>NZ_CP041193.1|WP_063084249.1|388169_388577_-|type-II-toxin-antitoxin-system-death-on-curing-family-toxin
MNQVKYLTAAEVLHLNETAIATLGGGNAGVQSPRAFEVVITQPQQIVFGQEMYSTIWLKAAYMMQQIVKTPVFVDGSKRTAMLVVQTFLTANGYDPTPDFFEDVQAFTIEVTQTSNTEAVMATIADWLASVFTER
>NZ_CP041193.1|WP_141146499.1|387174_388068_-|cation-diffusion-facilitator-family-transporter
MAHTHHHEIEQNNQTPYLIGIGLNLAFIIGEMIFAKLAGSTALFADALHSVSDVASLILSWLAVLVFGLKATRRRTYGFHNTTILASAINAILLLIAVGIIWFEAIDKLLNGKAHVDGDIVIWVALVGILVNFLAAHFFAKSGQQEHDLNARGAYIHLLADAGVSVGVVISGVLIALTGWNWIDPLVSALIGIVIVVSSWDVFKQSLNLLLNGVPAGIDEAGIANYLANHAEVKSVHDLHIWGISTTEAALTAHLAVTSTFNDADLDDITETLKHEFGIAHTTIQAETHLEVNCNTI
>NZ_CP041193.1|WP_010373795.1|386850_387159_-|winged-helix-turn-helix-transcriptional-regulator
MAQEQALLQAVAGFYKVLGNESRLAILHYMVMHPGPVYVSELVAQTGIAQPTVSKHLAILYQNHVVTRETSGNRVYYEIYDQHLKQTLEATFTHLEHMDISN
>NZ_CP041193.1|WP_081215792.1|396181_396859_-|type-II-A-CRISPR-associated-protein-Csn2
MRMFSLNFDFLDEPIKLEGFTELVIENRTVFTKVVQALYEYSDYEDYIQIFNEDYQALKANELMLVNDVLGFDINSATTLKLVYQDIIGQINDKPEVKSKIESYLNQAIQIIKDELVEFEIDLVSDEILLTEALKSLGVKIEIVSDTIFERFFEIIQVFKYLKAKELLVVINAGVYFSKSEIAAIAEYTELQNMNMLMINSAKYEGVKSRYVLDEDFVIMHEHMV
>NZ_CP041193.1|WP_063084252.1|396845_397181_-|CRISPR-associated-endonuclease-Cas2
MSYRFMRMILMFDMPMQSPEDKRTYRQFRKYLLSEGFLMHQFSIYSKLLLNDTANKAMLRRLEKNNPKVGNISLLTVTEKQFARMIYLNGEKSDSVANTDDRIVILGDEDV
>NZ_CP041193.1|WP_141146500.1|397177_398050_-|type-II-CRISPR-associated-endonuclease-Cas1
MGFRTLIINVHSKLSYKNNHLVFKTAEQTEMIHLSEIDTLLCETTDIVITTMLLDRLVNEGVLVIFCDSKRLPSSMLMPYYARHDSSLQVRRQTEWTPAIKSVVWTKIIAQKLANQASVLGGVDLIDKQVAVEKAAADLILDDPANIEAHVARTYFNALFGNDFVRDEPTEINKALDYGYALIMGLFAREVAKCGCITQIGIKHANQFNQFNLASDLMEPFRVLIDQIVYENRRETFPRIKRQLFNLFSNTYVYDDKEMYLNNIVSDYVRKIIDCLHEERENIPEFKVNG
>NZ_CP041193.1|WP_141146501.1|398261_399458_-|hypothetical-protein
MLTPKSGLTSQLRSGLIYELNPAFDEAKALDRGKAYQVERYTTIKLHDRFVKNRKLNDYHHAHDAYLNAFVAQYVYQEHPEWKNAWVYGKYPRNGQADFGKWATQRKQKSLQLLSSMANDVWNLEDPDTMEKTILNRDETFEQMRQTLCYRNINIVKKLETQTGKFGDESVYKKGNKADHYSLGLKRKYPPQKYGGTKGAISAVTALVKDNSGRVIPVSISASDYDSYQNASDKLAWLLMRKKNIAEILVASLPKYTKYELPSGALRLLASYQEAQSAVELPMLNLGLMDDEAKVLNLYDQLAQFIADNKLFTDKKIALLKGEMRVAFEGLEEFKDKQKVIDELLGVTNGSNQGLQALNSIGLGTSNQRLKSGNTMTNGVTLINESVTGLYSTRTTYN
>NZ_CP041193.1|WP_141146502.1|399495_402735_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MAKQKYTVGLDIGTNSVGWAVINQDFKLVSGKKHINDNGKQKRSRTNLWGVRLFDAAETAEDRRLKRGMRRRIARRKERLNYLRGIFQADILAFDDSFFIRMDESFLQDDDKQATAFSYRDQSGAMQTRVVTEKEAVKYPLFNGKSGSGETYTDESAYYNQYPTIYHLRQRLIDNPAQADLRLVYLAMHHILKYRGHFVNQGQTFDLGNINIAGNLTSALDKLDEASSFKFGLADVDADQANAVLKNKQWSASKKAYELNALFEIIQDTVYRRENETQAVAYDSLTVKQQEKWLAEKQKQVKAFLTGIVGNTISPKDIFANKDYDKKQNEDFPEKIKYSNENFEEQIGELEKYLDETEVAAIVAGKDVYESLVLSNILTKSTLSGSMIEKYNVHGAQLKSLKSFSRKVSAEFYDKLFNVVKDEKGKPHIGVYAQYIDGVGNPAKRLAREDFYDALKKVFESEFKGLTFPADEKGIDFTKTDLSADRVVFIREMNEAINLENYLPKQRQADNGAIPYQVHEHELIRIIENQMQYYPFLGDKVQVAYEDESGQTQVRSEYKIQVLFKFRIPYYVGTLAKNPGWVNEDGKKLVARNVAAKNSWVVRNSNEKVTPWNFEQVINKEASSINFIERMTNFDTYLPNEKVLPKNSLLYQEFIVNNELISSGYYLDGRKEYFLPEQRQRIITRLFKRYRKVSAKQMLDFLKNEYQIKLDDDPKKLFGLDTFVKAPSYNGSLSTVVELTKKIGISEDLIVNYPERFEEIIKWQTIFEDKKILKKTIREANHNKWSGMLTAEQVNKLSKRHYTGWGRLSQKLLDGVKTSQGRTIIESLREGIRDNFMRLIEDEKIAEFIANAQVAGAKDGVLAYDLVDQLPGSPAIKKGICQSLRVLQELEHYLGRDAIGKVVIEMSRDDESSMRTKARKQQLEEFYKKFKESTGSDVTAELKRELSKKDAKEIDDEKVFLYFLQNGKSMYSGDQLYLSRLADYQVDHIVPQTYIKDDSLDNKVLVTQRDNQNKGGDTPSQTVVTRMNSYWEMLAKNGQVSPRKLANLKKGPITLKQREGFINRQLVENRQITNHKACC
>NZ_CP041193.1|WP_010373842.1|402929_403448_-|YfcE-family-phosphodiesterase
MDYLIISDAHGDRQILVDVVDHYRGKVKAMFYNGDSELSRSDELFNDLMPVIGNMDTDPMFPDDRDYADDNFTLYQTHGHLVHTEVSLNQLREVASAKGVDVVTSGHTHVLGAEEIDGRLFINPGSIALPKGQYAYLGGTYAILTVEPTQFIVQFYTRDMQPVDGLRFTFKR
>NZ_CP041193.1|WP_108730631.1|403451_404048_-|XTP/dITP-diphosphatase
MAKLIFASKNEGKVREFREFLTPLGVEVVSLNELENVPTIIEDGNTFQENATIKAETIAKAFNVPVVAEDAGLTVDALDGAPGVHSARYAGDHDDAANNAKLLRELADVADDDRTASFHAVIVAIKPDGKRLVASGKVDGRILRAAQGSDGFGYDPLFFYEPFGKSFGELTPAEKNEISHRGAALQQFMSDFNAWWED
>NZ_CP041193.1|WP_010373846.1|404066_404912_-|glutamate-racemase
MDNRAIGYIDSGIGGLTVVKQALKQIPDEQVYYVGDTARMPYGPRPQEEVLGFTWQMVRYLLKKDIKMLVVACNTATAAALPDLQAKLDIPVVGVIQPGVDAALRKSADGEIGVIATAGTVKSLAYYNGLLQGNRAANVVQLAAPEFVDVAENHDYTSEFARQVVKEKLSYFKNHQVDTLILGCTHFPLMENFIQEAMGPQVTLVNSGAETISTVVEFLDKFDLRRASANPADHNDDEYFTTGSVKRFATIGGRWLDDKEMTVKHLDIIDDTLVLNEDVTD
>NZ_CP041193.1|WP_063084257.1|405071_405692_-|HAD-family-hydrolase
MKSFIFDVDGTLLSTESMYMKSLQQTLEENGIHKAYEELYAIFGLQSLDALIKFGIENPEEMQRQWQDHYHDFWDEVQLFAGVTDMLADLKATGVQLGIVTSNTPEEFADHADAFGINGYFDDFVFAGQTPKMKPAADPILKSMADLKATPETSIYIGDSVHDMHAAHNAGIKFGMAAWGVRDRAVFNDEAEFIFETPADILKLVD
>NZ_CP041193.1|WP_063084258.1|405755_406067_-|hypothetical-protein
MTKILFILIFIGDVLATPLFDSHPIFLIGTAVLAAATLYALYDMQSNRVNYAMTAILLLLAVSLFVLHGESDYLTVLNRVMMAQVAVSAILAVTYAGVRSQTA

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Crispr_ID: NZ_CP041193_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041193_2

1661634-1661741

Orphan

Consensus_repeat	Method
ACGGCGGTTTCTGATGCGCAAACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041193_2

>merge|NZ_CP041193|2|1661634-1661741|CRISPRCasFinder
ACGGCGGTTTCTGATGCGCAAACGGCCCGTGATAATGCTGAAACAGCGGCGAAGGCCGTGGATTCAAGTGGCTTTTCAACGGTGACGGCAGTTTCTGATGCGCAAACG

>NZ_CP041193|2|2|1661634-1661741|CRISPRCasFinder
ACGGCGGTTTCTGATGCGCAAACG	GCCCGTGATAATGCTGAAACAGCGGCGAAGGCCGTGGATTCAAGTGGCTTTTCAACGGTG
ACGGCAGTTTCTGATGCGCAAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041193.1\|WP_063083016.1\|1649469_1649712_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_063083030.1\|1679925_1680150_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_141146735.1\|1652647_1654900_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236140
NZ_CP041193.1\|WP_141146737.1\|1658258_1658870_+\|stage-II-sporulation-protein-M	unknown	unknown	gnl\|CDD\|376676
NZ_CP041193.1\|WP_141146736.1\|1655050_1656664_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340855
NZ_CP041193.1\|WP_141146742.1\|1680562_1681375_+\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|369561
NZ_CP041193.1\|WP_063083022.1\|1656663_1658178_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340855
NZ_CP041193.1\|WP_141146740.1\|1677143_1678508_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341046
NZ_CP041193.1\|WP_141146733.1\|1648442_1649312_+\|NAD-binding-protein	unknown	unknown	gnl\|CDD\|224995
NZ_CP041193.1\|WP_063083018.1\|1651136_1652006_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_063083017.1\|1649845_1650904_+\|DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP041193.1\|WP_043708081.1\|1680223_1680451_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_063083027.1\|1675488_1675743_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153123
NZ_CP041193.1\|WP_063083026.1\|1673539_1674928_+\|divalent-metal-cation-transporter	unknown	unknown	gnl\|CDD\|234815
NZ_CP041193.1\|WP_141146739.1\|1676193_1677147_+\|Dyp-type-peroxidase	unknown	unknown	gnl\|CDD\|367887
NZ_CP041193.1\|WP_141146741.1\|1679326_1679902_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_141146734.1\|1652161_1652647_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041193.1\|WP_010375198.1\|1647560_1648337_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|131468
NZ_CP041193.1\|WP_063083025.1\|1669283_1672259_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP041193.1\|WP_043708087.1\|1674946_1675405_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180

Protein	Function_ID	Function_description	E-value
NZ_CP041193.1\|WP_141146735.1\|1652647_1654900_+\|hypothetical-protein	gnl\|CDD\|236140	PRK08026, PRK08026, FliC/FljB family flagellin.	0.00013924
NZ_CP041193.1\|WP_141146737.1\|1658258_1658870_+\|stage-II-sporulation-protein-M	gnl\|CDD\|376676	pfam01944, SpoIIM, Stage II sporulation protein M. SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.	0.00176233
NZ_CP041193.1\|WP_141146736.1\|1655050_1656664_+\|glycosyltransferase	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	9.75258e-99
NZ_CP041193.1\|WP_141146742.1\|1680562_1681375_+\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	7.01173e-30
NZ_CP041193.1\|WP_063083022.1\|1656663_1658178_+\|glycosyltransferase	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	5.23794e-63
NZ_CP041193.1\|WP_141146740.1\|1677143_1678508_+\|MFS-transporter	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.06657e-53
NZ_CP041193.1\|WP_141146733.1\|1648442_1649312_+\|NAD-binding-protein	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	8.68096e-100
NZ_CP041193.1\|WP_063083026.1\|1673539_1674928_+\|divalent-metal-cation-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0
NZ_CP041193.1\|WP_063083027.1\|1675488_1675743_+\|hypothetical-protein	gnl\|CDD\|153123	cd02432, Nodulin-21_like_1, Nodulin-21 and CCC1-related protein family. Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter. .	2.70408e-11
NZ_CP041193.1\|WP_063083017.1\|1649845_1650904_+\|DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	8.06608e-21
NZ_CP041193.1\|WP_141146739.1\|1676193_1677147_+\|Dyp-type-peroxidase	gnl\|CDD\|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	1.21331e-71
NZ_CP041193.1\|WP_010375198.1\|1647560_1648337_+\|glucose-1-dehydrogenase	gnl\|CDD\|131468	TIGR02415, Diacetyl_reductase, acetoin reductases. One member of this family, as characterized in Klebsiella terrigena, is described as able to interconvert acetoin + NADH with meso-2,3-butanediol + NAD(+). It is also called capable of irreversible reduction of diacetyl with NADH to acetoin. Blomqvist, et al. decline to specify either EC 1.1.1.4 which is (R,R)-butanediol dehydrogenase, or EC 1.1.1.5, which is acetoin dehydrogenase without a specified stereochemistry, for this enzyme. This enzyme is a homotetramer in the family of short chain dehydrogenases (pfam00106). Another member of this family, from Corynebacterium glutamicum, is called L-2,3-butanediol dehydrogenase (). [Energy metabolism, Fermentation].	2.11707e-85
NZ_CP041193.1\|WP_063083025.1\|1669283_1672259_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	5.43717e-12
NZ_CP041193.1\|WP_043708087.1\|1674946_1675405_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	2.80476e-15

>NZ_CP041193.1|WP_141146737.1|1658258_1658870_+|stage-II-sporulation-protein-M
MTKIGTIWRETFRRYWRTMVIFAIINVVIWFVVLALVKFNAFGLHDLALKSIKANFVNDASSHKINHSGAFGGFVQLTWHNYLGGLATVAISLIPIPFWWVTAVMNPASIGYLLGLSPIPVTTFFAGIFPHSIVEMPMQWLEFSIAWETFRLIWQNIRTKQGWWHGVDWRRIITILIVVVLPMAIVTGAIESFITPALLNMAK
>NZ_CP041193.1|WP_063083022.1|1656663_1658178_+|glycosyltransferase
MNYFVSENVFTFNSGTEHAQAKRVQLFTEQGQLAQYVTRNYNRFLARDAEAIGLHAEQVLNMYDFFQGVTNVPREEVSLRLLPQIPLDEYHIEGHGPNYSTINHAGRELARINVMPATVGLVNDIIYYDRYGNTTARENFDWRGFKSSVDYFHPDGNLAVQKMLNLAGETVIEISHMKVNGTLYPTMWKLLNYKGHDWRFNTEDQLFLFFLNEITAEHPGSILVSDRRSLDHVVADVQFAAKKFAVLHDIHTPDIKNPIRGKLYDAYLNVLERRVRDFDAILVPTPEQQADLQKRYPGVDFRVVPDTFVPQAQLAAPRLRLPDRQAGNILFMGRLSPEKRPDQAIRALARVVKSVPSATLTFHGYPANAEILNELKALANQLGVTNSVIFGDYITSDALAAAYQRAQVIVQTSVAEGFGMNLVEAMSYGVPVVSYDITYGTRELIHDGVNGYVVANGAHGEMADRIVSILSDDGVWADLSAAAYDKAVTFNGQVMMAAWQQALQ
>NZ_CP041193.1|WP_141146736.1|1655050_1656664_+|glycosyltransferase
MNFFVNATMPKQKSGIEHAQLKRFELFNNHQVDSRIVLRDWDPVAHVNANAAGIPDNQLINMFDYFQEAVAVTPKTLHAQEIEFGVPNLQFADEPANNRYLVTAQNGQLVARVNYDATADKRVRSTELFDGYNNLFRVDHYDSRGFASLIQWYTTDNQIGTETWVTPSGRTVIETFNKKTMAGEFVKSGWRLIEHGGHVMQFDTIEELTKHFFDRLNDDFWSEEQPNVFVLDRSHLGDWGLLRLRNPAYVVMHLHNSHAGDAQDPMHAILNNHYEFAMNALDEYDAVVSATHKQTHDVNERFQPKTRLFTIPVGVVPDRLLQSERVPVARREFGKVIAVARIAWEKHLDDLVRAVGIVHKEFPQVTLDLYGYADPADNYKARTSVEEAIREYGLEGVVTMKGYTTEIDAVENNAMMYGLTSRMEGFNLAIMEAISHGLIAFSYDVNYGPNEIVEDDVNGNVVPYEDYEAMAQAMLKVLRDPDLAQRYSTGAYESSERYSEENVWHAWRELLDDAAAVWPAKLAAMPAHAHDLNKEAE
>NZ_CP041193.1|WP_141146735.1|1652647_1654900_+|hypothetical-protein
MSVTPGSWDSGTGISQAYIVAAGNKMPDGTGSTNSVPAFPDLTKLYRFSGKQYVYLHNPADTTGTMLTNISTQLRSGVAGMGVVVQFADGTMSDASTPTRIVGSYTGALRYYSLNLTTGIIQVQVGHILSTSTSRVTNLSWDAPVDAEKDEHWTNNNNKPASVIVVKQLKDVAALNWQLVLAGNVKLPSNGDTTQVSGDVRMFGAGGSTASLTYGVSGNATTTPTMVGSAIAYMSSYQEGGFNLLKNKTTDKGTITHDESYTDADGKSVTTGSYTGSQLVQLDKFTNTQSSDTTGTYTIDTGSSSVGFASDAIVLQNKNGDDVSAAVNMSGVTYKDATGATVTDSSKAKTATFTATLPAGASFTVKSKLVANAGQPAGITSTTTMAGKDANGDAVNLAGTFNWVPVTTVSGNITYVDATGATIATGKYTDKQPGSSTSDITAPTTTDGYRYKFVSADKATYDGSDIKVTVAKITTGNINYVYNGKTVSSTPFTDQEAGKTIANIAAPAGTVDGLRYKLADATKSYAYPDKDGDVNVDLAAIVSGTIKFVDADNNTLVKQQEFLDQTPGAQISPLTLPDGYVLAVDANGDVQSTYNYPTTDAQVVTVKVQKLTTGNRNDGMELTEVPSFSSDNNTIGASDTTTLTATKDGVLSYLNLKGQKADIYMSATDLKSNGSALPIKTLKANLSAGLADVYAANQTDGYGHMIVNDTTSKKGSLTIPDLQMTLSNNNFAAGTYSGTINYTMVSDDLN
>NZ_CP041193.1|WP_141146734.1|1652161_1652647_+|hypothetical-protein
MKNTRRLQAKVQHMALASIIIAGIVAPVTQLTPVFPGMSLQDVKAATTGTPDAVDKAGVIVENVRDQGQGVLPSNTPAQLAGQSGTMDNSWKISPLLPEQQANKIVNAKGDFRIQYASKTTEGNNTIYDGSQKSNNDSDKTSVTLTTPNVPQNTVPGQTAS
>NZ_CP041193.1|WP_063083018.1|1651136_1652006_+|hypothetical-protein
MMKQFLMRVAVLGAATALIAPAVSADTTAADQVNVANNQGKTTVTYVGDKTTDPSVVDPNPGDKGSTPEDGNNTTDNNGKQVKGLSLTAVPSFDFGKANKLAATTVATANGATDLTNATAGMKEAAAAAENSGKSSIFVNDTRGGNTGFKVYAAGSSLYDAAGNQLNVSALHLTVNNGVANGNQGVITGSKGVDVYHATNLTTNTSAAGTDTAQDTKDVLSGGTQANDMFGKVAGYGNLIATGNDKSTGDTATGAVSADLTLKTANALDGQAYNGTITYTLQDATLSAN
>NZ_CP041193.1|WP_063083017.1|1649845_1650904_+|DUF3324-domain-containing-protein
MIGRKLWSSLAIVTAALGALGVAKPAAAADYSNSNPEMGVMLSSIEDDTDTNNSTWELNTKPGKVLHGAVSVQNTSNESAKYTVSFEQARTNSQMNIMYSNGGTNKSLDPNMKLSKIAKVDGKDSATITVPANSTTALPVTLTMPAKEFDGYILGSVVVTKQVPKGYKVKDGFTNQFMYTKTVQITESIVNPTAVLTNTKKGGVKVVAGQQEFQLRIKNNEPSYIGNMKMSAKITYKKTGDVVLTDKQTGRSVAPNSSFTYRLPSERVMRAGKYHYVVTMTNEKTKKSWTFSNDFVVSQASATSVGIGRSIAFIPTWIWQLLALFLVLIGFLFFLLWKRRKDEDDEDEANAK
>NZ_CP041193.1|WP_063083016.1|1649469_1649712_+|hypothetical-protein
MTIGRIYSDLKAMFELLAWITFIFVLFVLSSRYLYGMDYSIFLPLVVMLYAGVWAGLSVALVLTWIFSAGAAKQATQTTK
>NZ_CP041193.1|WP_141146733.1|1648442_1649312_+|NAD-binding-protein
MKIGFIGTGVMGRGIINNLLQANYEVVVFNRTKAHAQSVLDNGATWADSPKEIAESADLVITMVGYPKDVEEQYYGDNGLFAGSHAGQIFVDMTTSTPTLAEQLAVDGEKYDVKVLDAPVSGGDVGAKNGTLTIMAGGDEAAYDSLQPIFDVISKAANRFGVAGRGQHTKMANQIMIAATMLGMSEMMVYAKAADLDVAKVMATLSAGGAQNWSLDNYGPRVLAGDFEPGFYAKHLLKDLRIALDEAAKMNLSLPATDLAEALYTKLVDQKNLGDEGTQTLVKLWAQFA
>NZ_CP041193.1|WP_010375198.1|1647560_1648337_+|glucose-1-dehydrogenase
MAEKVAIVTGGGQGIGEGIALRLAQDGYAVIVNGRTQTKLDNVVNKIVAAGGEATTFAGDVQQKSVNEEMVQLALTKYGRLDVFVANAGIDWVDTIEETPEEQVDNVFNINLKSQVWALQTAPAAMRKNGKQGGSIVLASSIAGMEGFEMLGIYSATKFATRGLVQAAAKELATDNIRVNAYNPGIVLTPMWDQIDARFAERKNVAIGETRQAFIDGILLGRGEEPDDIAKYVSFLVSDQADYITGQSLAVDGGVKFQ
>NZ_CP041193.1|WP_063083025.1|1669283_1672259_+|hypothetical-protein
MAAAKTTADDTIADQIAQMQDDLAAIQADVASLTEIAAKNPDDTLIAALLDDAKAQETLAQDKLADAQKQADAVADAPTMAAVTDLTDAVTQDAAATADALTQADRDVSDGQTKSDANLDAAKTAADVALADNIAQIKQNISDIQDDIATLTDLQDKNPGNTVIANLLADAQTQLAESQQSLADVTNLANQVEDQPTLADVQKIVDAAQTQTDYSDGDETQAQTDVDKAQAESNAKLNDAKQAATTAANQALQDIQQSIAGIQEDIRQLEQLVTDNPGDTTIANALADAQAQLDTAQATQTDAQQQAAKIAAATTLADVTAVTYQIAHDEASAGVDKEDADAALATGQQKSAENLAAAKDAAKQDLQDNIDAIQNNVAEIQKIVETITDIANKNPNDADIRAALTNAQNQLDKANDALTDAKQQLATVDDAKTLAQVAEKTAAGDADEKRSDQAVADAQTELKQAGAKSADNLADAVADAMKQADASLAAIQADIEQIKDDISQIRAIAAKNPDNQKIADLLADANMQLTEAQSRYQAAQAAKTELQDKNQTTTLADVTEKLQTISDKTTAADVDRKQADQDLANAKVAAADDLADAKQQATDAINQQLDRIDEQIKQIAQDIADLNDLAKQHPDSQAVKDALADAKQQLGDAQDAKQTAQDQLQQIGQATTPDAVNNLNDAAQAAGGAVTDAVKAANQDLADAKAAVANEMATAKDAAKDAVQQQINQLTDNVKQIQDIVDQLQNLVNQHPGNQALADKLASAQTQLKAAQQALDNARDQLAAIDAATTPADIAKAVNQIKVDQVVGQQALQTAQRLLADAQTIVAGLSTTATVVQAVSAGQTVPASAMLAYTVPQTVAVPGPVVTVTTTGAPEYRWAGMPVTSIDQATPAVGQTIGERTLAGAAAYRALDNKGARIQDRRVALSDINQTQQQDSHASLLRHGWRMPYYLSGRFMNDWHLNAANVATLLFFGTFLGWFFLPAKKKENEEE
>NZ_CP041193.1|WP_063083026.1|1673539_1674928_+|divalent-metal-cation-transporter
MENMTNGKHGLIQNAADDASLAEVNGTIVPPKNGSFWRKLWSFSGPGALVAVGYMDPGNWVTSVTGGATYHYLLLSIVLISSLIAMMLQYMAGKMGMVTGEDLAQATRNRTSKGGGIALWIITELALMATDIAEVIGGAIALHLLFGWSMIVSVLTTAFDVLLLLLLMRFGFRKIEAIVITLITTILFVFLYLVILSRPDISAMFGGYLPKLQSVSTHGITGADSPLVMTLGIIGATVMPHNLYLHSSIAQTRKVNRENKEELKESVRFMAWDSNIQLSVAFVINSMLLILGAAMFFGHADSVGTFGQMYNALGDKTIAGAIASPILSTLFAVALLASGQNSTITGTLTGEIIMAGFLHLRVPMWLRRVITRGLALIPVVAFTLIYGGAEDKLDQLLVYSQVFLSVALPFAMAPLIWMTSSKKIMGKEFVISKWMTTIAWLVFLVLTALNIQLVIQIVGKLL
>NZ_CP041193.1|WP_043708087.1|1674946_1675405_+|universal-stress-protein
MALELSDIQTSYQHVLVGVDESEQGQVALASAVHQALEDQAKLTIATVLELGELSTTDVLSLAAVNKRREDLEKNLQTYKNFAIAQGVTNVETVLADGAKAGEVLAMELAPETKADLLIVGAHSKQGMWPSLGSQAVYIARHAKISSMIARR
>NZ_CP041193.1|WP_063083027.1|1675488_1675743_+|hypothetical-protein
MAKDKQILAQRNNLIRASVMGANDGILSVSGIVIGVAGATTVAVALTGYLSALIGKGFASRAVKRNVIIGLLTITIHYTIGLFF
>NZ_CP041193.1|WP_141146739.1|1676193_1677147_+|Dyp-type-peroxidase
MAEMDYTKAQDVWKDVGQSVEFVVLGLDRTRPLAELQDAITEFADRSQAINCSMNVRAADGNLKVAIGFSYTAWKTLFPNKPVPAELEEFKGLKGPKYSMPGTAGDIFIHVRANDMSIVYEVVRQYMTVLHDVTTVIDETKGFRNFEGRAIIGFIDGTEVPSAADSAEVAVIGDEDPEFVNGSYAFAQKWLHDMDFWGQLKTEVQEKAIGRHKYDDLELEDEEKFHNAHNVSAKVEIDGEERQIVRMNVPFSEPALNKTGTYFIGYSRYWSVTKAMLTQMVEMSDYLLTFSQLMSGQLFFVPSRELLGDIADGEWTE
>NZ_CP041193.1|WP_141146740.1|1677143_1678508_+|MFS-transporter
MSETKQLGKRERTLFVWMMLLTSFSFSISQSAMTTIYPVMANHFSVPISMVQWLTTGFMLVMTVTMPLSPWLLNRVPFKWFLAGIQAMFLLGTFIAINATGFGWVIFGRVLEGTAVGFLFPSYQSVIMLITPEENRGANMGMVGLVMGAALATGPIVSGIISQWFNWQGVFIFFELVIGLLFLVNLFVGQNVIVKKDVHLDVPSLIGLFGFAMVLFSIQSLGHTTKLISMFAMMMVGLVLSVYFVHRQGNLSQPMLDFKVFKQVGFTLGLLLTGASYTALIVMTVLMPLYYQNVLHTSKLVSGLLMVPPAAAMAVMNRRSGKLLDQKGLKVVMRIGAASIFIGYAGLALTFGLHNAVLAVIFATFGEVGNAFMMLPATTYANNQLPDNLITHGSAMISTARQFAGVIGVLVATTIVSGLGNGLHSAYIIFALGMAVMIVTVWRITAIYHGENSL
>NZ_CP041193.1|WP_141146741.1|1679326_1679902_+|hypothetical-protein
MAWLLKINVARLGLFGFVIDHQKKFRFEGIALGSFVVFRNAKPTVLNLGILYAGGAVANVLVVMLLPLKAGLGVETFTLMNGVIAAVTLLPLNNLATDGSMLLNLVMNPEETVLHYTVSYFLTNEYTEKFDALLPQVLSTLDGPLGKVQESHIIIYLSYLNYVCALKKGRLENEQKQLVNKVFNAVLSDKK
>NZ_CP041193.1|WP_063083030.1|1679925_1680150_+|hypothetical-protein
MIGEVITQRLINSEDSVNDYKGLHKLPVLLKRRIAYLLDPEDTGKKADYYREITTTDQGEATLMINGELSYLAL
>NZ_CP041193.1|WP_043708081.1|1680223_1680451_+|hypothetical-protein
MEKANAIRKTANHDILVLAAVVMPSLIFPRTFRGFVIVALCYLAFCTFIYAVYFVFLKYTKMGLSRVEKYYRLDE
>NZ_CP041193.1|WP_141146742.1|1680562_1681375_+|alpha/beta-hydrolase-fold-domain-containing-protein
MTTDEFTKRFRPGTTTSGYLDDRAKAEIRAAGPSFDHQPTPTEIRAVMGWPAAHHEAANELTVRAHKIAGVSVTEFVQQQYDDQVLPAVVFIHGGAFVGGSVANVTPILQQMADAGALRVFALDYSLAPEHPFPAGMLDVYRVVVALHQAAKQYGIDETQLSLAGDSAGGNLTYTVALLDQNLQSNYLHKLVAMYPAVYNGHDAEKEMDFSDTQSYGAQADQALIAQYIASFRESPLIADWYLQGVDDEQMRFRRSMRQQRCLLRYRHHC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP041193_1	1.3\|395966\|28\|NZ_CP041193\|CRT	395966-395993	28	NC_006509	Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence	10844-10871	6	0.786
NZ_CP041193_1	1.3\|395966\|28\|NZ_CP041193\|CRT	395966-395993	28	NC_010420	Geobacillus stearothermophilus plasmid pGS18, strain 18	9842-9869	6	0.786
NZ_CP041193_1	1.8\|395968\|28\|NZ_CP041193\|PILER-CR	395968-395995	28	NC_006509	Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence	10844-10871	6	0.786
NZ_CP041193_1	1.8\|395968\|28\|NZ_CP041193\|PILER-CR	395968-395995	28	NC_010420	Geobacillus stearothermophilus plasmid pGS18, strain 18	9842-9869	6	0.786
NZ_CP041193_1	1.3\|395966\|28\|NZ_CP041193\|CRT	395966-395993	28	KC430106	Bacillus phage BPS10C, complete genome	157877-157904	7	0.75
NZ_CP041193_1	1.3\|395966\|28\|NZ_CP041193\|CRT	395966-395993	28	JN654439	Bacillus phage BPS13, complete genome	156571-156598	7	0.75
NZ_CP041193_1	1.3\|395966\|28\|NZ_CP041193\|CRT	395966-395993	28	NC_031034	Bacillus phage SalinJah, complete genome	32852-32879	7	0.75
NZ_CP041193_1	1.8\|395968\|28\|NZ_CP041193\|PILER-CR	395968-395995	28	KC430106	Bacillus phage BPS10C, complete genome	157877-157904	7	0.75
NZ_CP041193_1	1.8\|395968\|28\|NZ_CP041193\|PILER-CR	395968-395995	28	JN654439	Bacillus phage BPS13, complete genome	156571-156598	7	0.75
NZ_CP041193_1	1.8\|395968\|28\|NZ_CP041193\|PILER-CR	395968-395995	28	NC_031034	Bacillus phage SalinJah, complete genome	32852-32879	7	0.75

1. spacer 1.3|395966|28|NZ_CP041193|CRT matches to NC_006509 (Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence) position: , mismatch: 6, identity: 0.786

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
tttcaagaactttcaaccaatcatcttc	Protospacer
  ******** *****.********  *

2. spacer 1.3|395966|28|NZ_CP041193|CRT matches to NC_010420 (Geobacillus stearothermophilus plasmid pGS18, strain 18) position: , mismatch: 6, identity: 0.786

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
tttcaagaactttcaaccaatcatcttc	Protospacer
  ******** *****.********  *

3. spacer 1.8|395968|28|NZ_CP041193|PILER-CR matches to NC_006509 (Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence) position: , mismatch: 6, identity: 0.786

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
tttcaagaactttcaaccaatcatcttc	Protospacer
  ******** *****.********  *

4. spacer 1.8|395968|28|NZ_CP041193|PILER-CR matches to NC_010420 (Geobacillus stearothermophilus plasmid pGS18, strain 18) position: , mismatch: 6, identity: 0.786

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
tttcaagaactttcaaccaatcatcttc	Protospacer
  ******** *****.********  *

5. spacer 1.3|395966|28|NZ_CP041193|CRT matches to KC430106 (Bacillus phage BPS10C, complete genome) position: , mismatch: 7, identity: 0.75

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
aatcaagaacgttcaaacaataaaaggg	Protospacer
**************** **** *  ..

6. spacer 1.3|395966|28|NZ_CP041193|CRT matches to JN654439 (Bacillus phage BPS13, complete genome) position: , mismatch: 7, identity: 0.75

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
aatcaagaacgttcaaacaataaaaggg	Protospacer
**************** **** *  ..

7. spacer 1.3|395966|28|NZ_CP041193|CRT matches to NC_031034 (Bacillus phage SalinJah, complete genome) position: , mismatch: 7, identity: 0.75

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
aatcaagaacgttcaaacaataaaaggg	Protospacer
**************** **** *  ..

8. spacer 1.8|395968|28|NZ_CP041193|PILER-CR matches to KC430106 (Bacillus phage BPS10C, complete genome) position: , mismatch: 7, identity: 0.75

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
aatcaagaacgttcaaacaataaaaggg	Protospacer
**************** **** *  ..

9. spacer 1.8|395968|28|NZ_CP041193|PILER-CR matches to JN654439 (Bacillus phage BPS13, complete genome) position: , mismatch: 7, identity: 0.75

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
aatcaagaacgttcaaacaataaaaggg	Protospacer
**************** **** *  ..

10. spacer 1.8|395968|28|NZ_CP041193|PILER-CR matches to NC_031034 (Bacillus phage SalinJah, complete genome) position: , mismatch: 7, identity: 0.75

aatcaagaacgttcaatcaatcatcaac	CRISPR spacer
aatcaagaacgttcaaacaataaaaggg	Protospacer
**************** **** *  ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

580927 : 631929

Enterococcus_phage(39.29%)

capsid,protease,terminase,tRNA,tail,portal,head,integrase

attL 595287:595306|attR 631986:632005

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141146537.1\|580927_581653_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_010372458.1\|581654_581849_-	hypothetical protein	NA	NA	NA	NA
WP_010372455.1\|581851_582691_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_010372453.1\|582871_583267_+	large conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_010372451.1\|583484_584129_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	9.0e-45	45.0
WP_141146538.1\|584182_585631_-	LysM peptidoglycan-binding domain-containing protein	D2KRB9	Lactobacillus_phage	2.3e-11	34.2
WP_063082920.1\|586017_587523_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_003609051.1\|587621_587807_-	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_063082921.1\|587831_588788_-	YitT family protein	NA	NA	NA	NA
WP_010372861.1\|589002_590289_-	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_010372859.1\|590485_590842_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_043708158.1\|590959_591700_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_043708159.1\|591702_592206_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_063082922.1\|592366_593035_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_063082923.1\|593206_594010_-	hypothetical protein	A0A288TXV9	Enterococcus_phage	2.3e-50	51.6
WP_063082924.1\|594139_595096_-	TerC family protein	K7QKE8	Escherichia_phage	2.6e-40	35.0
595287:595306	attL	NA	NA	NA	NA
WP_141146539.1\|595593_597912_-	hypothetical protein	NA	NA	NA	NA
WP_141146540.1\|598113_599133_-	endolysin	I6PBG3	Weissella_phage	1.4e-15	41.8
WP_141146541.1\|599134_599455_-	hypothetical protein	NA	NA	NA	NA
WP_060654748.1\|599441_599672_-	hypothetical protein	NA	NA	NA	NA
WP_060654746.1\|599684_599933_-	hypothetical protein	NA	NA	NA	NA
WP_141146542.1\|600109_605335_-	hypothetical protein	A0A1B1SDS2	Weissella_phage	1.4e-140	61.0
WP_141146543.1\|605344_606241_-\|tail	phage tail protein	D2IYX7	Enterococcus_phage	4.5e-50	40.3
WP_141146544.1\|606250_609385_-\|tail	phage tail tape measure protein	A0A1B1SDY9	Weissella_phage	8.2e-99	55.4
WP_106443650.1\|609401_609608_-	hypothetical protein	D2IYX5	Enterococcus_phage	5.3e-07	46.0
WP_106443649.1\|609700_610147_-	hypothetical protein	D2IZN3	Enterococcus_phage	2.6e-14	33.8
WP_106443648.1\|610231_610846_-\|tail	phage major tail protein, TP901-1 family	D2IYX2	Enterococcus_phage	2.0e-57	55.4
WP_141146545.1\|610854_611223_-	hypothetical protein	NA	NA	NA	NA
WP_060654728.1\|611219_611582_-	hypothetical protein	A7J2A0	Streptococcus_phage	3.3e-12	38.1
WP_106443646.1\|611584_611869_-	hypothetical protein	NA	NA	NA	NA
WP_106443645.1\|611868_612210_-	hypothetical protein	Q597V3	Lactobacillus_virus	1.5e-19	45.8
WP_141146546.1\|612221_612560_-	hypothetical protein	NA	NA	NA	NA
WP_106443643.1\|612578_613481_-\|capsid	phage capsid protein	D2IYW7	Enterococcus_phage	6.9e-83	56.1
WP_106443642.1\|613498_614074_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	2.3e-15	44.4
WP_134658786.1\|614191_615127_-\|head	phage head morphogenesis protein	D2IYW4	Enterococcus_phage	4.5e-61	42.1
WP_060654715.1\|615113_616661_-\|portal	phage portal protein	D2IYW2	Enterococcus_phage	7.5e-162	58.4
WP_141146547.1\|616669_617950_-\|terminase	PBSX family phage terminase large subunit	Q4ZE37	Staphylococcus_virus	1.7e-140	57.6
WP_141146548.1\|617942_618365_-\|terminase	terminase small subunit	D7RWC4	Brochothrix_phage	7.5e-16	40.1
WP_141146549.1\|618683_619397_-	hypothetical protein	NA	NA	NA	NA
WP_141146550.1\|619579_620116_-	hypothetical protein	NA	NA	NA	NA
WP_141146551.1\|620692_621094_-	DUF722 domain-containing protein	E3W8E2	Leuconostoc_phage	4.6e-15	35.8
WP_141146552.1\|621094_621283_-	hypothetical protein	NA	NA	NA	NA
WP_141146553.1\|621286_621634_-	hypothetical protein	NA	NA	NA	NA
WP_141146554.1\|621630_621876_-	hypothetical protein	NA	NA	NA	NA
WP_141146555.1\|621875_622148_-	hypothetical protein	NA	NA	NA	NA
WP_141146556.1\|622442_622655_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_141146557.1\|622710_623079_-	hypothetical protein	NA	NA	NA	NA
WP_141146558.1\|623081_623807_-	ATP-binding protein	Q6J1V5	Lactobacillus_phage	1.6e-21	32.8
WP_141146559.1\|623806_624607_-	DnaD domain protein	A0A0S2MYA8	Enterococcus_phage	1.4e-39	57.3
WP_141146560.1\|624617_625094_-	single-stranded DNA-binding protein	A0A1B1SDU6	Weissella_phage	2.1e-43	59.5
WP_141146561.1\|625059_625770_-	hypothetical protein	D7RWH3	Brochothrix_phage	4.1e-38	42.9
WP_141146562.1\|625769_626411_-	hypothetical protein	A0A0S2MYH3	Enterococcus_phage	2.8e-14	35.8
WP_141146563.1\|626413_626602_-	hypothetical protein	NA	NA	NA	NA
WP_141146564.1\|626680_627208_-	hypothetical protein	NA	NA	NA	NA
WP_141146565.1\|627197_627386_-	hypothetical protein	NA	NA	NA	NA
WP_141146566.1\|627375_627600_-	hypothetical protein	NA	NA	NA	NA
WP_141146567.1\|627743_628031_-	hypothetical protein	NA	NA	NA	NA
WP_141146568.1\|628033_628789_-	phage regulatory protein	D2IYT0	Enterococcus_phage	1.4e-41	42.9
WP_141146569.1\|628800_629007_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_141146570.1\|629261_629606_+	helix-turn-helix transcriptional regulator	A0A141E189	Streptococcus_phage	1.6e-11	36.5
WP_141146571.1\|629606_630017_+	hypothetical protein	NA	NA	NA	NA
WP_118123307.1\|630085_630703_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_141146572.1\|630861_631929_+\|integrase	tyrosine-type recombinase/integrase	A0A0P0IXL3	Lactobacillus_phage	2.7e-33	31.4
631986:632005	attR	NA	NA	NA	NA

DBSCAN-SWA_2

722374 : 731016

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063082958.1\|722374_722968_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	3.1e-23	38.3
WP_141146582.1\|722958_723999_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F0L1	Synechococcus_phage	1.1e-55	40.9
WP_141146583.1\|724010_725546_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.8e-49	33.2
WP_063082961.1\|725530_727753_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.0e-139	41.1
WP_063082962.1\|727749_728433_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_043708231.1\|728434_728692_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_080774035.1\|728694_729420_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HWF9	Synechococcus_phage	1.1e-30	35.1
WP_063082963.1\|729416_730535_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_043711455.1\|730527_731016_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.7e-19	41.0

DBSCAN-SWA_3

1856444 : 1919428

Bacillus_phage(18.75%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141146474.1\|1856444_1857314_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.6e-20	28.4
WP_141146760.1\|1857706_1858786_+	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	1.4e-58	38.2
WP_141146761.1\|1859008_1860559_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.2e-20	31.5
WP_141146762.1\|1860560_1861700_+	ABC transporter permease	NA	NA	NA	NA
WP_043941415.1\|1861702_1862659_+	ABC transporter permease	NA	NA	NA	NA
WP_063083970.1\|1862720_1864085_-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_010371409.1\|1864236_1865226_+	rod shape-determining protein	NA	NA	NA	NA
WP_043710753.1\|1865228_1865438_+	DUF2969 family protein	NA	NA	NA	NA
WP_063083971.1\|1865459_1866650_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_043708872.1\|1866789_1867581_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_063083972.1\|1867619_1867868_-	hypothetical protein	NA	NA	NA	NA
WP_063083973.1\|1867982_1868732_+	hypothetical protein	NA	NA	NA	NA
WP_063083974.1\|1868995_1869799_+	HAD family phosphatase	NA	NA	NA	NA
WP_063083975.1\|1869864_1870365_+	methylated-DNA--[protein]-cysteine S-methyltransferase	NA	NA	NA	NA
WP_063083976.1\|1870385_1871201_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_063083977.1\|1871295_1871943_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_063083978.1\|1872092_1874072_+	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	1.7e-33	38.5
WP_063083979.1\|1874245_1875421_+	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_063083980.1\|1875424_1876126_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010371372.1\|1876252_1876753_+	DUF1097 domain-containing protein	NA	NA	NA	NA
WP_010371369.1\|1876990_1877602_+	30S ribosomal protein S4	NA	NA	NA	NA
WP_141146763.1\|1877751_1878912_+	MFS transporter	NA	NA	NA	NA
WP_063083982.1\|1879022_1879967_+	Dyp-type peroxidase	NA	NA	NA	NA
WP_141146764.1\|1880501_1882235_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_063083985.1\|1882379_1883093_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_043708889.1\|1883237_1883459_+	hypothetical protein	NA	NA	NA	NA
WP_141146765.1\|1883578_1884886_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.8e-44	31.9
WP_063083987.1\|1885131_1887714_+	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	6.8e-75	27.9
WP_010371348.1\|1887942_1889235_+	adenylosuccinate synthase	A0A2P1EKE7	Megavirus	4.0e-68	35.9
WP_063083988.1\|1889238_1889775_+	hypoxanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_141146766.1\|1889984_1890635_+	elongation factor G-binding protein	NA	NA	NA	NA
WP_063083989.1\|1890695_1891115_-	hypothetical protein	NA	NA	NA	NA
WP_063083990.1\|1891107_1891923_-	hypothetical protein	NA	NA	NA	NA
WP_141146767.1\|1892130_1892793_+	hypothetical protein	NA	NA	NA	NA
WP_063083992.1\|1892842_1893244_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_063083993.1\|1893260_1893587_+	hypothetical protein	NA	NA	NA	NA
WP_081215771.1\|1893856_1894861_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.8e-46	34.5
WP_063083995.1\|1895406_1895850_+	hypothetical protein	NA	NA	NA	NA
WP_063083996.1\|1896052_1896955_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_063083997.1\|1897255_1898878_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_063083998.1\|1898889_1900056_+	amidohydrolase family protein	NA	NA	NA	NA
WP_141146768.1\|1900131_1901988_+	hypothetical protein	NA	NA	NA	NA
WP_063084000.1\|1902035_1902635_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_141146769.1\|1904335_1906828_+	ATP-binding cassette domain-containing protein	A0A1B1IVR3	uncultured_Mediterranean_phage	2.5e-122	30.3
WP_043941382.1\|1906918_1907761_+	aldo/keto reductase	A0A1V0SDE7	Indivirus	4.4e-23	30.3
WP_043708921.1\|1908025_1908874_+	DegV family protein	NA	NA	NA	NA
WP_063084004.1\|1909090_1909852_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_063084005.1\|1909907_1910339_+	DUF1810 family protein	A0A2H4UVK5	Bodo_saltans_virus	5.9e-16	40.4
WP_141146770.1\|1910409_1911279_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.0e-19	28.0
WP_141146483.1\|1911320_1911638_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_141146771.1\|1911701_1912001_-\|transposase	transposase	NA	NA	NA	NA
WP_141146772.1\|1912311_1912908_+	thymidine kinase	A0A249XZX5	Enterococcus_phage	8.1e-40	47.6
WP_010371283.1\|1913165_1913492_+	multidrug resistance protein SMR	NA	NA	NA	NA
WP_010371280.1\|1913491_1913815_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_141146773.1\|1914277_1915303_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	NA	NA	NA	NA
WP_043941376.1\|1915302_1915890_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.0e-26	42.7
WP_141146774.1\|1917103_1917568_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	8.0e-27	45.3
WP_043708937.1\|1917674_1918481_+	membrane protein	NA	NA	NA	NA
WP_141146474.1\|1918558_1919428_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.6e-20	28.4

DBSCAN-SWA_4

2172280 : 2286003

107

Lactococcus_phage(37.14%)

capsid,protease,terminase,tRNA,portal,head,integrase,transposase

attL 2228735:2228751|attR 2267197:2267213

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141146829.1\|2172280_2172748_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_141146830.1\|2172749_2173259_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_063083840.1\|2173278_2173812_+	3'-5' exonuclease	A0A0A8WJ41	Clostridium_phage	4.7e-07	27.0
WP_063083839.1\|2173829_2174726_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_010369943.1\|2174749_2176801_+	Na+/H+ antiporter	NA	NA	NA	NA
WP_043941158.1\|2176812_2177646_+	TIGR00159 family protein	NA	NA	NA	NA
WP_063083838.1\|2177645_2178623_+	hypothetical protein	NA	NA	NA	NA
WP_010369937.1\|2178631_2179990_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_010369936.1\|2179994_2180309_+	hypothetical protein	NA	NA	NA	NA
WP_063084342.1\|2180612_2182463_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_063084343.1\|2183244_2184150_+	aspartate carbamoyltransferase catalytic subunit	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.5e-24	28.6
WP_063084344.1\|2184149_2185436_+	dihydroorotase	NA	NA	NA	NA
WP_141146831.1\|2185432_2186515_+	carbamoyl phosphate synthase small subunit	R4TGJ8	Halovirus	4.3e-55	36.3
WP_141146832.1\|2186507_2189687_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_063084347.1\|2189710_2190670_+	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_081215797.1\|2190675_2191395_+	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_063084349.1\|2191397_2192036_+	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	5.3e-05	31.0
WP_043709773.1\|2192195_2193443_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_063084350.1\|2193439_2194468_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_141146833.1\|2194472_2195492_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_010369896.1\|2195488_2195743_+	DUF1797 family protein	NA	NA	NA	NA
WP_141146834.1\|2195865_2198070_+	sulfatase-like hydrolase/transferase	W6LM83	Streptococcus_phage	3.9e-140	43.6
WP_010368840.1\|2204137_2204440_+	hypothetical protein	NA	NA	NA	NA
WP_108730106.1\|2204449_2205403_+	ADP-ribosylglycohydrolase	A0A1S6UB21	Serratia_phage	2.8e-26	28.0
WP_141146770.1\|2205494_2206364_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.0e-19	28.0
WP_141146599.1\|2206405_2207086_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_063084356.1\|2207207_2210009_-	YfhO family protein	NA	NA	NA	NA
WP_043709678.1\|2210301_2211282_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_010368852.1\|2211333_2212146_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_010368857.1\|2212165_2213113_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_010368859.1\|2213234_2213579_+	DUF956 family protein	NA	NA	NA	NA
WP_043941647.1\|2213609_2214275_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_043709687.1\|2214489_2214882_-	hypothetical protein	NA	NA	NA	NA
WP_063084355.1\|2215060_2215912_+	DNA-entry nuclease	NA	NA	NA	NA
WP_010368871.1\|2216283_2216667_+	helix-turn-helix transcriptional regulator	A0A1J0MG99	Staphylococcus_phage	2.2e-14	47.3
WP_010368874.1\|2216656_2217115_+	hypothetical protein	NA	NA	NA	NA
WP_010368877.1\|2217159_2217339_+	hypothetical protein	NA	NA	NA	NA
WP_010368880.1\|2217478_2217691_+	hypothetical protein	NA	NA	NA	NA
WP_043709693.1\|2217833_2218544_+	hypothetical protein	NA	NA	NA	NA
WP_010369259.1\|2218818_2219829_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_010369262.1\|2219951_2221178_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_063084353.1\|2221316_2222189_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_043941642.1\|2222342_2223791_+	cardiolipin synthase	NA	NA	NA	NA
WP_043709699.1\|2223861_2224278_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	5.1e-25	44.0
WP_141146835.1\|2224692_2227389_+	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_043942025.1\|2227460_2227910_-	universal stress protein	NA	NA	NA	NA
WP_108730109.1\|2228030_2228885_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.9e-46	38.1
2228735:2228751	attL	NA	NA	NA	NA
WP_141146836.1\|2229152_2231003_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	5.8e-20	24.9
WP_010374216.1\|2231138_2231381_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_141146837.1\|2231617_2232595_-\|integrase	tyrosine-type recombinase/integrase	Q6EVM3	Oenoccocus_phage	3.4e-43	34.2
WP_141146838.1\|2232799_2233000_+	hypothetical protein	A0A1P8BMQ1	Lactococcus_phage	5.3e-20	74.2
WP_141146839.1\|2233035_2233401_-	hypothetical protein	NA	NA	NA	NA
WP_141146840.1\|2233620_2234043_-	ImmA/IrrE family metallo-endopeptidase	E3W8B8	Leuconostoc_phage	1.3e-12	34.4
WP_141146841.1\|2234029_2234380_-	helix-turn-helix transcriptional regulator	A0A141E1M3	Streptococcus_phage	4.3e-09	34.3
WP_141146842.1\|2234777_2235110_-	hypothetical protein	NA	NA	NA	NA
WP_141146810.1\|2235575_2236370_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	6.1e-27	34.7
WP_063084397.1\|2237096_2237612_+	HNH endonuclease	Q9AZM8	Lactococcus_phage	2.3e-51	54.2
WP_063084398.1\|2238347_2238812_+\|terminase	phage terminase small subunit P27 family	B8R648	Lactobacillus_phage	9.5e-20	39.9
WP_063084399.1\|2238814_2240641_+\|terminase	terminase large subunit	Q9AZM6	Lactococcus_phage	1.6e-267	73.7
WP_063084400.1\|2240818_2241889_+\|portal	phage portal protein	Q9AZM4	Lactococcus_phage	5.8e-121	59.7
WP_141146843.1\|2241888_2242473_+\|head,protease	HK97 family phage prohead protease	Q9AZM3	Lactococcus_phage	1.4e-65	64.1
WP_141146844.1\|2242465_2243761_+\|capsid	phage major capsid protein	Q9AZM2	Lactococcus_phage	1.1e-110	53.2
WP_063084403.1\|2243826_2244132_+	hypothetical protein	Q9AZM1	Lactococcus_phage	4.3e-21	54.3
WP_063084404.1\|2244118_2244454_+\|head	phage head closure protein	Q9AZM0	Lactococcus_phage	1.1e-25	51.4
WP_063084405.1\|2244456_2244933_+	hypothetical protein	Q9AZL9	Lactococcus_phage	4.8e-35	48.1
WP_063084406.1\|2244932_2245319_+	DUF806 family protein	Q94MA5	Lactococcus_phage	2.9e-14	36.7
WP_141146845.1\|2245356_2245968_+	hypothetical protein	Q9AZL7	Lactococcus_phage	5.9e-70	70.3
WP_063084408.1\|2246098_2246458_+	hypothetical protein	Q8LTK3	Lactococcus_phage	2.4e-07	31.1
WP_063084409.1\|2246682_2246976_+	hypothetical protein	Q9AZL5	Lactococcus_phage	1.9e-26	68.0
WP_063084410.1\|2247015_2248056_+	hypothetical protein	A0A1S7FYZ4	Listeria_phage	9.9e-17	30.5
WP_141146810.1\|2248360_2249155_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	6.1e-27	34.7
WP_141146846.1\|2249541_2250708_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_043712300.1\|2251289_2252669_+	amino acid permease	NA	NA	NA	NA
WP_141146847.1\|2252772_2254287_+	carboxypeptidase M32	NA	NA	NA	NA
WP_141146848.1\|2254655_2256011_+	sodium:proton antiporter	NA	NA	NA	NA
WP_043940693.1\|2256102_2256498_-	ribonuclease HI family protein	NA	NA	NA	NA
WP_010374198.1\|2256564_2256948_+	hypothetical protein	NA	NA	NA	NA
WP_063084171.1\|2256944_2257859_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_010374194.1\|2258029_2258539_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_063084172.1\|2258599_2259685_+	carbamoyl phosphate synthase small subunit	NA	NA	NA	NA
WP_063084173.1\|2259681_2262150_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_141146849.1\|2262215_2263226_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_063084174.1\|2263377_2264673_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.2e-18	31.8
WP_010374184.1\|2264767_2264980_+	CsbD family protein	NA	NA	NA	NA
WP_010374183.1\|2265250_2265724_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_010374181.1\|2265726_2266185_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_141146850.1\|2266196_2267168_+	beta-ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_141146851.1\|2267254_2267494_+	acyl carrier protein	NA	NA	NA	NA
2267197:2267213	attR	NA	NA	NA	NA
WP_141146852.1\|2267526_2268474_+	enoyl-[acyl-carrier-protein] reductase FabK	NA	NA	NA	NA
WP_060655412.1\|2268495_2269437_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_010374173.1\|2269436_2270159_+	3-oxoacyl-ACP reductase FabG	W8CYX9	Bacillus_phage	2.9e-07	35.4
WP_010374171.1\|2270246_2271482_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_141146853.1\|2271481_2271949_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_043712314.1\|2271961_2272393_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_063084177.1\|2272394_2273771_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_063084178.1\|2273783_2274629_+	acetyl-CoA carboxylase, carboxyltransferase subunit beta	NA	NA	NA	NA
WP_010374161.1\|2274628_2275414_+	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_063084179.1\|2275528_2276203_+	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_063084180.1\|2276219_2277365_+	hypothetical protein	NA	NA	NA	NA
WP_063084181.1\|2277452_2278481_-	peptidoglycan bridge formation glycyltransferase FemA/FemB family protein	NA	NA	NA	NA
WP_141146854.1\|2278684_2280409_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.0e-184	57.0
WP_010374151.1\|2280520_2280841_+	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_063084183.1\|2280850_2281885_+	serine hydrolase	NA	NA	NA	NA
WP_010374148.1\|2281956_2282526_+	LemA family protein	NA	NA	NA	NA
WP_010374146.1\|2282543_2283440_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_063084184.1\|2283492_2285028_-	hypothetical protein	NA	NA	NA	NA
WP_141146855.1\|2285133_2286003_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.1e-20	28.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP041193

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection