CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP041230	Bacteroides xylanisolvens strain H207 chromosome, complete genome	3 crisprs	PrimPol,PD-DExK,WYL,cas3,RT,DEDDh	1	1	9	2
NZ_CP041231	Bacteroides xylanisolvens strain H207 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP041232	Bacteroides xylanisolvens strain H207 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041230_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041230_1

2965293-2965369

Orphan

Consensus_repeat	Method
TTGCGCAAGAGGCTCTTGCGTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041230_1

>merge|NZ_CP041230|1|2965293-2965369|CRISPRCasFinder
TTGCGCAAGAGGCTCTTGCGTAAATTCTTTTGATTGAAATATATTTGTCTGAAATTGCGCAAGAGGTTCTTGCGTAA

>NZ_CP041230|1|1|2965293-2965369|CRISPRCasFinder
TTGCGCAAGAGGCTCTTGCGTAA	ATTCTTTTGATTGAAATATATTTGTCTGAAA
TTGCGCAAGAGGTTCTTGCGTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041230.1\|WP_141408973.1\|2985909_2988234_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|366567
NZ_CP041230.1\|WP_128858972.1\|2975176_2975695_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274376
NZ_CP041230.1\|WP_141408961.1\|2953825_2955493_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP041230.1\|WP_141408967.1\|2967223_2969869_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041230.1\|WP_004315272.1\|2959108_2960272_+\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237047
NZ_CP041230.1\|WP_004325025.1\|2956270_2957815_+\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP041230.1\|WP_004301902.1\|2958450_2959020_+\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NZ_CP041230.1\|WP_165861481.1\|2972239_2975014_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP041230.1\|WP_141408966.1\|2965595_2967023_-\|DUF4419-domain-containing-protein	unknown	unknown	gnl\|CDD\|379593
NZ_CP041230.1\|WP_141408970.1\|2975740_2978977_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP041230.1\|WP_141408962.1\|2960268_2961081_+\|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl\|CDD\|376831
NZ_CP041230.1\|WP_008775531.1\|2955856_2956078_+\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|371235
NZ_CP041230.1\|WP_120067517.1\|2961131_2961797_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225917
NZ_CP041230.1\|WP_141409620.1\|2983009_2985766_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041230.1\|WP_141408964.1\|2962507_2963689_-\|beta-propeller-fold-lactonase-family-protein	unknown	unknown	gnl\|CDD\|378416
NZ_CP041230.1\|WP_141408971.1\|2978991_2980947_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|369630
NZ_CP041230.1\|WP_004308350.1\|2957855_2958392_+\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
NZ_CP041230.1\|WP_167509109.1\|2980972_2982799_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238338
NZ_CP041230.1\|WP_141408963.1\|2961825_2962464_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|366703
NZ_CP041230.1\|WP_141408968.1\|2969886_2971530_+\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|366525

Protein	Function_ID	Function_description	E-value
NZ_CP041230.1\|WP_141408973.1\|2985909_2988234_+\|beta-galactosidase	gnl\|CDD\|366567	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.	2.72006e-68
NZ_CP041230.1\|WP_128858972.1\|2975176_2975695_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274376	TIGR02985, Sig70_bacteroi1, RNA polymerase sigma-70 factor, Bacteroides expansion family 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.	3.10732e-32
NZ_CP041230.1\|WP_141408961.1\|2953825_2955493_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.19273e-14
NZ_CP041230.1\|WP_004315272.1\|2959108_2960272_+\|GTPase-ObgE	gnl\|CDD\|237047	PRK12298, obgE, GTPase CgtA; Reviewed.	0
NZ_CP041230.1\|WP_004325025.1\|2956270_2957815_+\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	3.76871e-117
NZ_CP041230.1\|WP_004301902.1\|2958450_2959020_+\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	6.0643e-98
NZ_CP041230.1\|WP_165861481.1\|2972239_2975014_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.78731e-13
NZ_CP041230.1\|WP_141408966.1\|2965595_2967023_-\|DUF4419-domain-containing-protein	gnl\|CDD\|379593	pfam14388, DUF4419, Domain of unknown function (DUF4419). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, eukaryotes and viruses. Proteins in this family are typically between 348 and 454 amino acids in length.	1.14186e-103
NZ_CP041230.1\|WP_141408970.1\|2975740_2978977_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP041230.1\|WP_141408962.1\|2960268_2961081_+\|peptidoglycan-editing-factor-PgeF	gnl\|CDD\|376831	pfam02578, Cu-oxidase_4, Multi-copper polyphenol oxidoreductase laccase. Laccases are multi-copper oxidoreductases able to oxidize a wide variety of phenolic and non-phenolic compounds and are widely distributed among both prokaryotes and eukaryotes. There are two main active catalytic sites with conserved histidines that are capable of binding four copper atoms.	4.86872e-91
NZ_CP041230.1\|WP_008775531.1\|2955856_2956078_+\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|371235	pfam10771, DUF2582, Winged helix-turn-helix domain (DUF2582). This family is conserved in bacteria and archaea. The function is not known. The structure of two proteins in this family were solved using NMR and shown to adopt a winged helix-turn-helix fold. Structural analysis shows that these proteins form an unusual dimeric conformation. This dimer was shown to be similar to that found in the FadR and TubR wHTH domains. It was suggested that these proteins are not very likely to bind to DNA.	5.76247e-28
NZ_CP041230.1\|WP_120067517.1\|2961131_2961797_+\|hypothetical-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	2.56611e-37
NZ_CP041230.1\|WP_141408964.1\|2962507_2963689_-\|beta-propeller-fold-lactonase-family-protein	gnl\|CDD\|378416	pfam10282, Lactonase, Lactonase, 7-bladed beta-propeller. This entry contains bacterial 6-phosphogluconolactonases (6PGL)YbhE-type (EC:3.1.1.31) which hydrolyze 6-phosphogluconolactone to 6-phosphogluconate. The entry also contains the fungal muconate lactonising enzyme carboxy-cis,cis-muconate cyclase (EC:5.5.1.5) and muconate cycloisomerase (EC:5.5.1.1), which convert cis,cis-muconates to muconolactones and vice versa as part of the microbial beta-ketoadipate pathway. Structures of proteins in this family have revealed a 7-bladed beta-propeller fold.	1.80286e-149
NZ_CP041230.1\|WP_141408971.1\|2978991_2980947_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	7.62703e-39
NZ_CP041230.1\|WP_004308350.1\|2957855_2958392_+\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	7.92823e-63
NZ_CP041230.1\|WP_167509109.1\|2980972_2982799_+\|hypothetical-protein	gnl\|CDD\|238338	cd00604, IPT_CGTD, IPT domain (domain D) of cyclodextrin glycosyltransferase (CGTase) and similar enzymes. These enzymes are involved in the enzymatic hydrolysis of alpha-1,4 linkages of starch polymers and belong to the glycosyl hydrolase family 13. Most consist of three domains (A,B,C) but CGTase is more complex and has two additional domains (D,E). The function of the IPT/D domain is unknown.	2.414e-08
NZ_CP041230.1\|WP_141408963.1\|2961825_2962464_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	2.4876e-38
NZ_CP041230.1\|WP_141408968.1\|2969886_2971530_+\|glycoside-hydrolase	gnl\|CDD\|366525	pfam01229, Glyco_hydro_39, Glycosyl hydrolases family 39.	1.47167e-84

>NZ_CP041230.1|WP_141408964.1|2962507_2963689_-|beta-propeller-fold-lactonase-family-protein
MIKTYLSKTSIFKAFAAVCIFGISISGCTSKKKTPMETTDTTENELTMLVGTYTSGTSKGIYSYRFNEEDGTATPLSETEVENPSYLVPSADGKFVYAVSEFNNTQAAANAFAFNKEKGTLQLLNSQQTGGEDPCYIIASGNNVITANYSGSSISVFPIAKDGSLLPVSDIIQFKGTGIDKERQEKPHLHCVRITPDGKYLFADDLGTDQIHKFIINPAANAENKEAFLKEGSPAAFKVKAGSGPRHLTFSPNGHYAYLINELSGTVIAFEYKDGDLKEIQTIAADTVNAQGSADIHISPDGKFLYASNRLKADGIAIFSIHPDNGMLAKAGYQLTGIHPRNFIITPNGKYLLVACRDSNVIQVYERDTDTGLLTDVQQDIKVDKPVCIKFVP
>NZ_CP041230.1|WP_141408963.1|2961825_2962464_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MKNILILLTVLLLPLTADGQDKPFFSAREMADVRVATPGLFAKSNHIYLHLDSLKDHEYAFPLPGGKVISAYGTRGGHSGTDIKTCAKDTIRAAFDGVVRMSKPYYAYGNIVVIRHANGLETLYSHNFKNLVKAGDVVKAGQAIGLTGRTGRATTEHVHFETRINGQHFNPNLIFDLKERTLRKECIKCTKNGSKIVVKTQIPDNRIAQNKK
>NZ_CP041230.1|WP_120067517.1|2961131_2961797_+|hypothetical-protein
MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYSEGLWQEINAFAGQLTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDLINLVSLRTGHSIGGFDADKIQGTRLELGIGKAGERFEGIGRGVLNIEGLPVYRDSFGGIGTPTSDHERTKMDLGTTHILAIVNGYNGKEGLREAAEMIQTLLRNYTESDGGEIVFFE
>NZ_CP041230.1|WP_141408962.1|2960268_2961081_+|peptidoglycan-editing-factor-PgeF
MISLTKHNELKGYKSLEAYPEVAHFVTTRHEGISTGTYGSFNCSPYTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQNHGCASLIINESFFKESLEMRRLLLRGMDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHLNKMFGTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANRIELLNRRVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRILSGIMIRK
>NZ_CP041230.1|WP_004315272.1|2959108_2960272_+|GTPase-ObgE
MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRGGHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAETGEYLCDVTEDGQEVILLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLADVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIEGASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLAVTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVHRPKDVTRLQQELKDMGEDEDIVYEYEEDVDDDDDIDYEYEEEDWEEK
>NZ_CP041230.1|WP_004301902.1|2958450_2959020_+|adenylate-kinase
MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTELGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAERGQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNEKKYQHINGLGTMEGIFAEICEAVDKL
>NZ_CP041230.1|WP_004308350.1|2957855_2958392_+|hypoxanthine-phosphoribosyltransferase
MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSVLNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDIVDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDYDGFGRNYPDIYTVVD
>NZ_CP041230.1|WP_004325025.1|2956270_2957815_+|peptide-MFS-transporter
MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKEAAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTNLAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPLICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKKEDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLILLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASWFQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVPGVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAGMLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE
>NZ_CP041230.1|WP_008775531.1|2955856_2956078_+|winged-helix-turn-helix-domain-containing-protein
MEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIGWLAREDKIFLRKREGMLFASIENVEFTFG
>NZ_CP041230.1|WP_141408961.1|2953825_2955493_-|ISL3-family-transposase
MQQAISTTYKYTSKKENPPTNRGLFHDFRFSPGYDNLQQDGISEAVGSLTVFLHTAGKGASCPYCGHFSHRLHSYYSRHIQDLEVYGHTLELVIKVGKYYCENVSCPRKIFCEPLSFLARRYGRRSYLVEERIRSISLELTSRKASSLLQLFHITASSSSCLRILQQYGQHNPMHNKSIYVGIDDFAYKKGKDYMSVVVDQMTHMPIALLEDRSGEALDNWLIRNPQIQYITRDRGRCFTEAINRIIPGVTQICDRFHLTKNMTDTMIPEIEKMIRQTKQKLKYEYPDRDTASSLILQDIFNMGDVRHREKLKIYRESLNLKMQGMTIEQTAAHLGKKSRYIYKLIHNRRIGAYLNEQQKTALKYVSELATIISAGCITRKILAQKMGSKISGALIGRITSSLRKMYQQKRKEVKEHNESIENGSKTQRVSQNQIRKYILKGESDNPKLAELYKSSPQIKELLSVCQNFRDMINGNTYDKDIRKWIEKAKATRNMALTNFAYGIEKDWEAVQAAIDIPFSNGLLEGTVNKIKAVKRQMYNRAGSKLLRAKILYSQ
>NZ_CP041230.1|WP_141408966.1|2965595_2967023_-|DUF4419-domain-containing-protein
MKNTLFCLFIFCSVSTFAQNGITFKVEKLSKPEELLHLHSPNEIYENLILSDMNIEPYEIKKKNIKVPYHIIAKSESPDSLVSFGPNSFFNGMYQAYADHRPFVLSPDIIWLLISQGFARHINANQESMRNELVDFSGKLSLIVREDKKLEDPTLSWEKIFPQFTEQISQYAGNHLTELLTCNFSTTTSLEKVASEITIMEAVKPYFEFIIIRIVCGIPEITLEGTPEDWEKLLHKARGLKEYKLDWWISELEPLLEEFVKASKGEVNKNFWRNMFKYHSQKRYGAPNIIDGWIVKFFPYDKEGKRNNLKQLEGRNCLPDEIVKVDVKYQEVYGDAVKETPLEFWAGFIGLEQNSKTFALRPQIGWMVRKKDVNKEGLKSKLSADAQKDGWGSGINIRVKEFPAVLLELKEIKRLDIQFIDTINIPDEISKIKIESLNLYGKITKEGIERIKRLLPDTDIKINGSRGGSASFMTP
>NZ_CP041230.1|WP_141408967.1|2967223_2969869_+|hypothetical-protein
MKNILLLILVCLGNMWTLKAQEHPVIYASASDKATILQKIADEEWAKEAFTKIRGNVEKYADRHTADPQWIISRLAMYWKEGERYTQCYLKNQNWDRGEGDAPVPTVRMPGMRTWNKYYNVPLEDRQPYNETGDMLGLNRQNPSAPPVLVPYKESGHMVRGNNVEILTLAENAAFVYWVTGEEKFARFAADIFNTWLIGTYYMNPILDPEKSTGGTGGWEPGGICGYYDYEQIHDDLALHAATVYDFLYDYLNANPHVHLKEIGKETKEVAGVVFKRFIDIGFIRGGKSGNWNVNGWNMILRPILVLEENEAYPDGKGKDYYLHYLTNESTIYHDAIPDMVKTYDPVTGLWPESPGYSFGTIQMLLDWAILLKRSGIDVIADNPILQKAAMAVFPWMDDAANMVVFGDSRGGSANFLTFENLLTYYTQTANKKGIESTASALNKGLSLGKYNRSNAGWTGICTYAPTIPVVKSETSERTSYSPHHRFITMKNWTGPFKMMAALYGGTDGYHLTANGLALQLYGYGYALAPDAAAYESYWSKDHVYHQSPVGANTILPGYSEGKIVIEAMEPMVESGKFVNEKALTPFLNFADISAGEKRRTVALVRTSDSDGYYIDIFRSDLNDNDYLFHNVGTNLEVVDVRGNILPFNQQDKFERTYHAGYEWFTNIRKTEYARNFIASWTMPENITARLWMTGEKGRQIYKVDAPATTLNKGLTPGNVSMPPSVTPTLIVRQEDNNAKAHPFVSVYEAYKGDTPHVKQVTAMSVGENCAGVKVLTGNKREDYVFSATDSQVYSLASRTFFSGTFGLISEVGGKIYSMYLGKGRLLQKGNYSLEAEQNVYATIYQVDGNWFYSATGPVKVKIGKMERILDEGYNKLLNIK
>NZ_CP041230.1|WP_141408968.1|2969886_2971530_+|glycoside-hydrolase
MDKKNFFVTLAAAALFAVPVSSQTIDVKGDAEPFTHYWSVGVGAGRANEGLRAGWLEHLKLVKDYCGFQYVRMHGLFGDDMFVYFKKPDGRVVYNWQYIDEVYDRMLALGVKPFVELSFFPKDIAAKDSKQQMWYQNNVSVDRNNFDKWHNLVKEFTQHVVDRYGIDEVLTWYFEVWNEPNLNLNPKAGFFDGTKSDYFRMYKESVKAIKSIDKRLKVGGPATSNFIADNRHDGEIMDHKKSVFYSQDIINTKQWKGVWIEDFLRFCEKENLPVDFISTHPYPTDYALDPDTGRSKDAIRYVHSLHDDITWLRQQIASSKYPDAEVHLTEWSTSPNSRDRMHDVLPPAAYILKTNLDCLGMANSLMYWTFTDVFEEKGGGEEIFHGGFGMINFQGLVKPSFHAYRMLHQLGDEKLYYKDPLFVSRSSRTGKISAVAFNYPSEYEEAVPSAANFNNYMQASSKKVDIALKGLKPGTAFEIEILDKDHGNVYDDYLKIGAPHSPGYKEIDYLRQAAWNTDKQIIKVNSEGTFVWKSELAPWSCMLIREL
>NZ_CP041230.1|WP_165861481.1|2972239_2975014_+|helix-turn-helix-domain-containing-protein
MKNILIVLFIILLNILNPQYLLAIDLKFNRLTAENGLPYSTANVMLQDDNGFLWIGTHTGLCRYDGINTEIYSEFENRQVRSLEETEGNWLWVGMENGLARINLKTRKMESILCEGKKELQRVSTIHWGKDEKVYVAAIDGLFVYDKGILTHVIADEGQVFSILENTLTDYWLLTEKALLNLDTKTGKVTRYAWPLKFNPFFLASLNSHKNVLYISAEYNSMLRFDMKNRRFMNEFAIEDKKRTYPLIIDGGQLFVNTTWGIEVLSCTTNRLQYTIVADDDMKNGLRSNQFYSMYKKGTTLWLGIFSGGIAYSQIENDAFNVYRLPGTDFTTFNRQVRSFCIVSDDIKLIGTRNGLLLVSEKEKRVQTFTTQDYPALLSNSILFIQPFGGDDYLIGTTKGLVLYSLKKNSFRIFSEENVYKGTQFYSCLSDEEGIWLATSEKVLYYNMHTNQTDIYPLDTNKYPGCSALSLCFDSRNRLWIGTSEGVFLLDKVTHKITDTFEGKDKLKNISKAQINNISRSKNGKMFICTDRMGLIVLNERGSEIDIYSEDNILPHNTVYSVYEDEQNVWWIATMKGILRYNRVTNKKQLYDLSAGIPGGVCRSFCKDSQNRYWWANEMGLVVCDPYQLSQAVLCDLPRISSVKVAGKRQQLLEDQEQGLVTPAYAKSMVLPAFQNNLELCFSMHTYLGALDSYQYILEGFDEKWKYNIENNCLSYTDLPAGKYLLRVRGQGNSDYETQLEIIVEYPWYVTYGIVAIVVIIVLLGIGWKYWRRKVAIVEMKQDTDDELLNTAAYRPKTPRSSQEKLDRLYEQLIHYFETEKPYLNKQLKSADIAAALSCSISSLSECLSFKLNTNFSDFVAHYRVEAFVQKQKQEDISLYTLMSIAESCGFNSKSSFFRLFKKQMGCTPLEYIQKQDHDRVSKQ
>NZ_CP041230.1|WP_128858972.1|2975176_2975695_+|sigma-70-family-RNA-polymerase-sigma-factor
MENVTDRSQSIIIDSYIEYYSRVVDFITYRINNRCDAEDLAQDVFIRLMEYKQILCEDTVKHFIYTISRNIVTDYLRRYYKAREISSYLYDETSSACTNETEETVLANDISSLEKKKMATFPRQRKQIYYLTRFKGLSSVEIATRLNVGKRTVECHLFMARKEMRTYLQQCI
>NZ_CP041230.1|WP_141408970.1|2975740_2978977_+|SusC/RagA-family-TonB-linked-outer-membrane-protein
MENDFLRFSPKRVLYSVVMASTLWVGSPQLVFSEVRDVQAILQSGFVKGQVVDEKGEPIIGASISVKGTTNGVITDMDGNFTLNNISGGVLIISYVGFQTQEVNITGKPLKIVLREDSEMLDEIVVVGYGVQKKATLSGSVTQVKGDEVLAGKSTQSVASALQGTIPGLTITRTSSRPGNEGTSITLRGGISVNDDANKPMIIIDGVEAYEWELSQINPNDVESISVLKDAAAAIYGTKAAGGVMLVTTKRGQEGKIKVTYSGSVHANIVGKRYPVANGQEWAQMHNMAVENDYKYGADHTYGWKLGWSEETWRSLANGEYIEGMVNGAYKVLDPYADQFDAVYGTTWGQSHNVMVRGGNDRVKVMTSLGYANDRSLIDVAYDGQKKYNFRTNLDYKINDIVKTEFNVSYDKRNTSSPQQGVGHGLQDMYLFPIYNEYGQFYDTFGNNNLVAKMVEGGRNNNTEEIMRLGGKLTLDLNKYVKGLSLQTSANFRIRHHKKIERQTHVTLYDWAGETTSIDGYPDYSQGSGSIHYQSSDDDCWVKNTLEETFYQTYNALLNYNRSFGSHNVSLMAGLTGEKTGYEKYYQYRKGMANDELDDINLGDVTTAEATGGRNEVGMISWIGRLNYDYKGIYLLEGLFRRDGSSRFSKNNRWANFYGLSAGIRFSEFEFVKNWNVFDNLKLRGSYGETGSQGGIGQYDYYSTISKGNTVFGFDGTKVNTAWISSMTSEDRTWERVSTTNVAVDFAVLNNRLSGTFEYYIRKNNDMLIDITYPKTLGATAPKTNSGGYRANGWELQLNWNDRIGRDFSYSVGLSLSDARTKVTSYEGAAAITYGKNKIVEGKPINSIYVFKTNGYLQNEEEVTAYYGTINGTGTLAPTQNSNNQLRPGCVRKVDLDENGAITTDDLYYYGDSNPHYQFGISLGAKYKGFDFSAFIQGVGKQNLIREGNMRGPFVSWWMNQNKTYLDNTWTEGNTDARFPLLSFNGSVNDWNYSQYNDINVMNVWYARLKNVALGYTLPKTWMKKIGVENLRLYISADNLFELTHVDDKFDPEAQASTGQGKIDCYARTISFGIDLTF
>NZ_CP041230.1|WP_141408971.1|2978991_2980947_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTGKVIYILLLGSLVVTSCIDDFLNLKPLDSETEAIFFQNLEQFQAAADNLHTNIYAWQSNGKKGSANNTYAIRFDYGTDLITVSHDAVNGTNAAGTSDDYYSQSYEWLRGCNQLIEKAASYSNPNEIAGPVGQAHFFRAWHHFFLLQRFGGIPLMMSTPDVSSDVVWGKRASRYEVVKAILDDLDTAIFNLKNTTVSSTSNDGHVTIEAAKAFKARVCLYEGTWEKYNGIGAADPTNGDGVKNGAGTVIPDGYPSVTDFLTMAKTLSDEIISSGTFELFLGVENVPNSANPDLYAHKSYFYLFNLEGSDSNPSGLSKASNKEAIFRAVYDHTNRKSNMNLTHSEPAKMTRKLIDMYLCADGLPVHVSPLFKGYIDMNTEFENRDYRLTACHPKTLDYVWGWGKYGTGADYMTDITSLSANQYQYCPNLTTNTASGTRGRKFCSELSTITDAGQEAMDCMLIRLAEIYLIYAEATCELGNGTISDEDLDKSLNLVRARGGVAPLNAALIAKARTLGCDMSYLGEIRRERALELYAEGLRIADVCRWGIAEQVFGTEKCGVYISYEDTNTYLVTMKNPVTNEDVFKSSVWTADNIEQETITYEDPAYTPTKPGCVIVEKKVNRKFSKKNYLQPIPTDEIKLNPQLLQNPQW
>NZ_CP041230.1|WP_167509109.1|2980972_2982799_+|hypothetical-protein
MKKLFNSIMICVLLFSSTFIGTACSDDDKNGSNKYPVPVISEFSPSEGLPTSVVTIKGANFGTERTERVGRVYFGGVEATDYESWSDNEIKVRVPQKGITGNITLWVWKNHTETTDEFICVPGAEITSINPSPTFPGSQITINGKNFQYFIDKGVTAQDVIVEFCAEEGITKATADALTATSVTVTVPTDAKGGVITIDFDGYQKVSGPELPLVGDLNLPLINYLETSGTITIEEGGIGSTKDGAYVIYQFDAPATGLFDVYLMTGTTKDGSSLNVNIGDNLNTLKTAALNETLTHAMKNTGSWATNWKDQWGAFYLEEGKTYYLKITFLQVGTTWVGNVGEIGLTLSADQNQTPVNGVKPGVDYVIYKHDFNSGTSYLPFTDAWAWEPNYIKIVDKYLEFYYNYKALLEDDRRMRRGAEVTCNFKTTTEGWYGFKVYLPEGKFPMNESGIIIAQIFGQGCKNSWAGHLSIDQGTLKFSHRHALVDPVVGTVGKLEVNKWYSVVVYFKVGRNNKGRLKAWIGDDMAEGSPAYDSGNCNFGFAHWIDDDTLDDTGNNPECAGYNGTYDALGCKFGLYVSNKVDITIRFDDLKALEGSPSGAFNIVKPGN
>NZ_CP041230.1|WP_141409620.1|2983009_2985766_+|hypothetical-protein
MLDVWIAFAQSTISEKDFRTNMHPRVFVTMDDKQAIQAKIESVNWARDIYEALKTDVDPIIAMHQDNPGYVVSRMQMHWEPGKRYTHFYTEGNYVIRREGNAKYPTVRVTYGRAASNSVPLAPLDKIIPYGDGSLTKPVSTNLGIVKLTESSNNKLSDLGNETPYDTVPFTKTGLGTETVNRAFIQLAWKSSILYYLTEDKKYAKLAADILWNFVRGAAQQEQLNPGWEQNHKEGSFNGYLSFETLGDTRHFATLPLAYDMIYDYLRQEYFDSEQFVKGIDGEMWAPPHPEGKEWALGCFEKMFKRLIENKLNRGGGLKGNWNMNEQQSAMLYALALDEDSTYQDGKGRAYYVNKLVYGPTTEHHGAYLDVLRANISPTTGLWPEAPGGYGQGSIGQLVRFGFIYYKNGLDFLSKDPLLSKASSSMTQMLFPNGYVTNFGDATYATMNTEQLELMMAYWHDKKDSLQERKCAEWMKYAPQRNLHNEFYYALFFYLPEIPRTDSAPQLARTSYSETYSLIFGRNNAPDPKDALAFTLMGFGKDTGHRQPNGMNMELYGRGHILAPDQGVGQDYWGADTHEYKINVAGHNTVSPNGKGADNNMPQNLEIVHAEPVVVDGKAPDYEVSPYHQYVDAVNHFYTPEIKAEQRRMLSIIRTSPQTGYYVDIFRSEVTDGEDRYHDYIYHNMGTGSEFFLSSGQPMLMSASPLDSLSGKGYSYFTTLGSYENPDNFYVDYHLGIDDTHMRMFVPTGKGRTVYQLNSLFNHRYYEPSLRTLPVPALLIRQKSEAWDHPFIAVYEPYGNGAKSQIRSVYTSKTPKQKGVAKLSVEYFKKDKMDHIIHSVNEKTEAKYMGIRFMGTYCVVTMEKGRLVSLYIGNGYSFSMDGLEVSLDEGKPFDVWLEWRDGEWICHSREAVKIKMLK
>NZ_CP041230.1|WP_141408973.1|2985909_2988234_+|beta-galactosidase
MKKYIVGLLGFLPMFMSAQNITDLAVMNDQTADSFIGNGTQISSIDDSVFIHPDRIRYDRQCIQIEGKDIFLFSAAFHYFRVPQPLWPDRFRKLKEGGFNCVETYIPWNWHERKMPRSPQDESCLDMRELDDFLKMAEDFGLYVIVRPGPYICAEWSGGGFPQWIMQKKPAKTTFDTWLQSNDPEFMRWNEHWYRVVCRVVAPHQLTRKSKGHTGVIFFQVENEFNRIKWFPKEAKKDYLIQLTQIVRKYEIDVPVITCWTDEARNVEEGVLNGVVDMVNSYPRWEIEKNFGRLINQQLRTQPGKPLISGELQGGWMSEVGGKLSWEQDGLMPVQTQNITLYALQRGFCGINYYMTVGGTNFDDWGARQMTTTYDYAAAIAENGSTNERYRCFQGLAHLLKEHGTKIARADVLPIEYISTDPDVKLVLRKASNGDRYYFVRTEEHTRHHFGTIQTSDLTFDFSLEPFGAMIYYLPSGGSQGDWLPKLPDTESRPAVEADTIRLTPDMQMADPLPTRWTKLEKGECIDHDGIYGRHFVYYRTYAPQGKLLEVGRIGHKLINGTDADEVLVSVQGKILPMLKEDAYSVFYQLPGDSAINRKLEIVMLFESKGLHHHTKKIVEDYWGIGLNYVRCGDKELSLEYAYTENERGLNLSKGGGLQEKILPETAELDESLLSWYSYSFTLPEQPRGVWFPYHLRLEHSGNGFIYINGHCIGRCWQKGPQHEYYIPECWLNIGGENHLVVSLCPTRDGAEIRGAEIIPVTWVAERREKLVVD

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Crispr_ID: NZ_CP041230_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041230_2

4030789-4030909

Orphan

Consensus_repeat	Method
CAGCACCGATAGCAGCACCTTTACC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP041230_2

>merge|NZ_CP041230|2|4030789-4030909|CRISPRCasFinder
TCTTACCGATAAGAGCACCTGTACCTGCACCTACTGCCGTACCAATAGCAGCACCGATAGCAGCACCTTTACCTTTACCGATAACACCTCCCAGGATCGCACCTAGTGCAGCACCCGAACC

>NZ_CP041230|2|2|4030789-4030909|CRISPRCasFinder
TCTTACCGATAAGAGCACCTGTACC	TGCACCTACTGCCGTACCAATAG
CAGCACCGATAGCAGCACCTTTACC	TTTACCGATAACACCTCCCAGGA
TCGCACCTAGTGCAGCACCCGAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041230.1\|WP_004316871.1\|4020090_4021362_-\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP041230.1\|WP_004311582.1\|4025489_4026113_+\|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl\|CDD\|225415
NZ_CP041230.1\|WP_141409184.1\|4042679_4045337_-\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP041230.1\|WP_004311593.1\|4038243_4041489_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|379297
NZ_CP041230.1\|WP_004311581.1\|4024311_4025397_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|340819
NZ_CP041230.1\|WP_008022103.1\|4031173_4032526_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240545
NZ_CP041230.1\|WP_004300346.1\|4028799_4029303_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP041230.1\|WP_004311592.1\|4036335_4038027_+\|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl\|CDD\|236992
NZ_CP041230.1\|WP_120080457.1\|4029573_4030317_-\|monofunctional-biosynthetic-peptidoglycan-transglycosylase	unknown	unknown	gnl\|CDD\|234603
NZ_CP041230.1\|WP_141409181.1\|4018986_4019943_-\|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240639
NZ_CP041230.1\|WP_004326932.1\|4032617_4034003_+\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|238865
NZ_CP041230.1\|WP_008775885.1\|4048192_4048969_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP041230.1\|WP_141409183.1\|4041536_4042634_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197318
NZ_CP041230.1\|WP_141409182.1\|4021368_4023945_-\|carboxypeptidase-like-regulatory-domain-containing-protein	unknown	unknown	gnl\|CDD\|372685
NZ_CP041230.1\|WP_008022096.1\|4026311_4026809_-\|DUF4251-domain-containing-protein	unknown	unknown	gnl\|CDD\|372897
NZ_CP041230.1\|WP_141409186.1\|4046652_4048209_-\|spore-coat-protein-CotH	unknown	unknown	gnl\|CDD\|378045
NZ_CP041230.1\|WP_141409185.1\|4045407_4046622_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133061
NZ_CP041230.1\|WP_087317920.1\|4034196_4036068_+\|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP041230.1\|WP_004313396.1\|4027999_4028560_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|377192
NZ_CP041230.1\|WP_008643886.1\|4026991_4027954_-\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320699

Protein	Function_ID	Function_description	E-value
NZ_CP041230.1\|WP_004316871.1\|4020090_4021362_-\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP041230.1\|WP_004311582.1\|4025489_4026113_+\|trimeric-intracellular-cation-channel-family-protein	gnl\|CDD\|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	3.2089e-53
NZ_CP041230.1\|WP_141409184.1\|4042679_4045337_-\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	7.37577e-67
NZ_CP041230.1\|WP_004311593.1\|4038243_4041489_+\|TonB-dependent-receptor	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	5.75632e-18
NZ_CP041230.1\|WP_004311581.1\|4024311_4025397_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|340819	cd03786, GTB_UDP-GlcNAc_2-Epimerase, UDP-N-acetylglucosamine 2-epimerase and similar proteins. Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family (EC 5.1.3.14) are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues (UDP-ManNAc) for use in the biosynthesis of a variety of cell surface polysaccharides; The mammalian enzyme is bifunctional, catalyzing both the inversion of stereochemistry at C-2 and the hydrolysis of the UDP-sugar linkage to generate free ManNAc. It also catalyzes the phosphorylation of ManNAc to generate ManNAc 6-phosphate, a precursor to salic acids. In mammals, sialic acids are found at the termini of oligosaccharides in a large variety of cell surface glycoconjugates and are key mediators of cell-cell recognition events. Mutations in human members of this family have been associated with Sialuria, a rare disease caused by the disorders of sialic acid metabolism. This family belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	8.88802e-113
NZ_CP041230.1\|WP_008022103.1\|4031173_4032526_-\|MATE-family-efflux-transporter	gnl\|CDD\|240545	cd13140, MATE_like_1, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	0
NZ_CP041230.1\|WP_004300346.1\|4028799_4029303_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.06862e-34
NZ_CP041230.1\|WP_004311592.1\|4036335_4038027_+\|energy-dependent-translational-throttle-protein-EttA	gnl\|CDD\|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP041230.1\|WP_120080457.1\|4029573_4030317_-\|monofunctional-biosynthetic-peptidoglycan-transglycosylase	gnl\|CDD\|234603	PRK00056, mtgA, monofunctional biosynthetic peptidoglycan transglycosylase; Provisional.	3.22764e-120
NZ_CP041230.1\|WP_141409181.1\|4018986_4019943_-\|D-2-hydroxyacid-dehydrogenase	gnl\|CDD\|240639	cd12162, 2-Hacid_dh_4, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	0
NZ_CP041230.1\|WP_004326932.1\|4032617_4034003_+\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|238865	cd01827, sialate_O-acetylesterase_like1, sialate O-acetylesterase_like family of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	2.65991e-100
NZ_CP041230.1\|WP_008775885.1\|4048192_4048969_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.63582e-11
NZ_CP041230.1\|WP_141409183.1\|4041536_4042634_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197318	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps, proteins.	6.6052e-92
NZ_CP041230.1\|WP_141409182.1\|4021368_4023945_-\|carboxypeptidase-like-regulatory-domain-containing-protein	gnl\|CDD\|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	1.56772e-17
NZ_CP041230.1\|WP_008022096.1\|4026311_4026809_-\|DUF4251-domain-containing-protein	gnl\|CDD\|372897	pfam14059, DUF4251, Domain of unknown function (DUF4251). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 164 and 196 amino acids in length.	3.61754e-57
NZ_CP041230.1\|WP_141409186.1\|4046652_4048209_-\|spore-coat-protein-CotH	gnl\|CDD\|378045	pfam08757, CotH, CotH kinase protein. Members of this family include the spore coat protein H (cotH). This protein is an atypical protein kinase that phosphorylates CotB and CotG.	5.51682e-34
NZ_CP041230.1\|WP_141409185.1\|4045407_4046622_-\|glycosyltransferase	gnl\|CDD\|133061	cd06439, CESA_like_1, CESA_like_1 is a member of the cellulose synthase (CESA) superfamily. This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.	3.42071e-108
NZ_CP041230.1\|WP_087317920.1\|4034196_4036068_+\|PAS-domain-containing-sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.65413e-57
NZ_CP041230.1\|WP_004313396.1\|4027999_4028560_-\|LemA-family-protein	gnl\|CDD\|377192	pfam04011, LemA, LemA family. The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.	3.71781e-75
NZ_CP041230.1\|WP_008643886.1\|4026991_4027954_-\|M48-family-metallopeptidase	gnl\|CDD\|320699	cd07340, M48B_Htpx_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	1.04134e-107

>NZ_CP041230.1|WP_120080457.1|4029573_4030317_-|monofunctional-biosynthetic-peptidoglycan-transglycosylase
MHKQLLIKKLLRYTRNLLIFFFTSTLLAVIIYRFMPVYVTPLMVIRSVQQVFSGDKPTWKHTWVSFDKISPNLPMAVIASEDNRFAEHNGFDLVEIKKAMKENETRKRKRGASTISQQTAKNVFLWPQSSWVRKGLEVYFTFLIELFWSKERIMEVYLNSIEMGNGIYGAQATAKNKFGTTADKLTRGQCALIAATLPNPIRFNSAKPSSYILKRQSQILRLMNLVPKFPPEEKAVEKKKSKKKKSK
>NZ_CP041230.1|WP_004300346.1|4028799_4029303_+|RNA-polymerase-sigma-factor
MKSLSFRKDLIGVQEELLRFAYKLTANREEANDLLQETSLKALDNEEKYVPDTNFKGWMYTIMRNIFINNYRKIVRDQTFVDTTDNYYHLNLPQDSGFESTEGAYDLKEMHRIVNALPREYKIPFSMHVSGFKYREIAEKLGLPLGTVKSRIFFTRQRLQQELKDFV
>NZ_CP041230.1|WP_004313396.1|4027999_4028560_-|LemA-family-protein
MTILIIVGIIVLLGIIFASMYNSLVKLRNNRENAFADIDVQLKQRHDLIPQLVDTVKGYAAHEKETLDRVIQARNGAVGAKTIDDKIAAENQLSSALAGLKITLEAYPDLKANQNFLQLQEEIADVENKLAAVRRYFNSATKEYNNAVQTFPSNIVAGMTGFQREIMFDLGKNERANLDQAPKISF
>NZ_CP041230.1|WP_008643886.1|4026991_4027954_-|M48-family-metallopeptidase
MQYVGIQTQQSRNNLRSAFLLFLFPCLVAALLYLSCYLLVLFGYGKSMEIEIMPMVNHFFLSSLPYTMGIVIIWFLIAYWANTSIINSATGSKPLDRIENKRVYNLVENLCMSQGMKMPKINIIYDSSLNAFASGINERTYTVTLSEGIIKKLNDEELEAVIAHELSHIRNRDVRLLIISIVFVGIFSMLTEITLYTITHIRVRSNSKGSGGIFLFILLALVIAAIGYLFSSLMRFAISRKREYMADAGSAEMTKNPLALASALRKISADPAIEAVERKDVAQLFIQNPKKKSKSIFSGINGLFATHPPIEKRIEILEQF
>NZ_CP041230.1|WP_008022096.1|4026311_4026809_-|DUF4251-domain-containing-protein
MRTKKQIFMLLLALLVGIPTLSAQSKKEKKEQKKEAVKKLIESENYKIDVNTAMPMRGRSIPLTSSYSLEIRNDSVISYLPYYGRAYSIPYGGGDGLNFKAVLKEYSMEMDKKGNAVIEFIARNPEDRYEYRVKVFPNGSASIDVNMQNRQSISFQGELYIKEEK
>NZ_CP041230.1|WP_004311582.1|4025489_4026113_+|trimeric-intracellular-cation-channel-family-protein
MPTFVQILDFIGTFAFAISGIRLASAKRFDWFGAYVVGLATAIGGGTIRDVLLDVTPGWMTDPIYLICTGLALLWVICFGRWLIRLNNTFFIFDTIGLALFTVVGVGKSIALGYPFWVAIIMGSITGAAGGVIRDVFINEIPLIFRKEIYAMACVVGGIAYWICDLAGMESYACQLIGGSAVFLTRILAVKYHICLPILKGGEEPEE
>NZ_CP041230.1|WP_004311581.1|4024311_4025397_-|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKITIVAGARPNFMKIAPITRAIEAARALGKSISYRLVYTGRKDDTSLDASLFSDLDMKAPDVYLGVESSNPTSLTAGIMVAFEQELTENPAHVVLVVDDLTATMSCAIVAKKQGIKVAHLVAGTRSFDMKMPKEVNRMITDGLSDYLFTAGMVANRNLNQTGTESENVYYVGNILIDAIRYNRNRLLKPIWFSVLGLQEGNYLLFTLNRRVLLGNKENLRQLMKTIIDKSAGMPIVAPLHTYVRNAIKELDIEAPNLHIMPPQNYLFFGYLINKAKGIITDSGNVAEEATFLGIPCITLNTYAEHPETWRMGTNELVGEDPALLAKTMDTLMHGEWKRGELPERWDGRTAERIVQILTSK
>NZ_CP041230.1|WP_141409182.1|4021368_4023945_-|carboxypeptidase-like-regulatory-domain-containing-protein
MIQRYNKILILFLLVLVASNAFAQQIKGVVTDSITHEPLMYISVYYQEKRDMGTITNIDGEYSLEARRNGGTLVFSAVGYISKTVRVGSNNQTVNVKLAPDNVLLNEVVVKPQKEKYSRKNNPAVEFMKKVIEHKKAQVLEVNEYYQYDKYEKMKMSINDLTPEKLEKGIYKKYSFLRDQVEVSETTNKLILPISVQETSSQTIYRKNPENKKTIIKGKNSNGIEEFFSTGDMLGTVLKDVFADINIYDDDIRLLQQRFVSPIGNNAISFYKYYLMDTLMVNKRECVHLTFVPQNSQDFGFTGHLYVLNDSTYAVQKCTMNLPKKTGVNFVNRMDITQQYEQLPNGNWVLADDDMTVDLSWNSNKTAGGLQVERTTKYSNYKFDPIEQRLFRLKGSVIKEADMLSKSDEYWASVRQVPLTKKESSMDVFVNRLEQIPGFKYIIFGAKALIENFVETGSKEHPSKVDIGPINTMISSNYIDGTRFRLSGMTTAHFDKHWFLSGYGAYGLKDERWKYSGTVTYSFNKRDYVVWEFPKHYLSATYSYDVMSPMDKFLFTDKDNIFLSVKTTTVDQMSYMRDATINYELETLTGFGVKAMLRHRNDEPTGKLEYLRNDAAQTRVHDVTTSEASLTLRYAPGESFVNSKQRRVPVSLDAPIFTLTHAMGFKGVLGGDYNFNRTEASVWKRFWLPASWGKIDCSVKAGAEWNTVPFPLLILPEANLSYITQRETFNLINNMEFLNDRYASMSLSYDMNGKLFNRIPLIKNLKWREMFRVRALWGTLTDKNNPFKSNNPDLFRFPTRDGKFTSFVMDPKVPYVEASVGIYNIFKLLHVEYVHRFTYRDNPGINKNGIRFMVLMVF
>NZ_CP041230.1|WP_004316871.1|4020090_4021362_-|replication-associated-recombination-protein-A
MQPLAERLRPKTLDDYIGQKHLVGPGAILRKMIDAGRISSFILWGPPGVGKTTLAQIIANKLETPFYTLSAVTSGVKDVREVIERAKSNRFFSQSSPILFIDEIHRFSKSQQDSLLGAVENGTVTLIGATTENPSFEVIRPLLSRCQLYVLKSLEKEDLLELLQRAITTDAVLKERKIELKETTAMLRFSGGDARKLLNILELVVQSETEETVVITDEMVTERLQQNPLAYDKDGEMHYDIISAFIKSIRGSDPDGAIYWLARMVEGGEDPAFIARRLVISAAEDIGLANPNALLLANACFETLMKIGWPEGRIPLAETTIYLATSPKSNSAYSAINDALELVRSTGNLPVPLHLRNAPTKLMKQLGYGQEYKYAHSYEGNFVKQQFLPDELKDKRIWQPQNNPAEQKHAERMIQLWGDKFKK
>NZ_CP041230.1|WP_141409181.1|4018986_4019943_-|D-2-hydroxyacid-dehydrogenase
MKIVVLDGFAANPGDLSWEGMKVLGECTIYDRTAPEEVLERAAGAEAILTNKVIINADHMAALPELKYIGVLATGYNVVDTAAAKERGIVVTNIPSYSTASVAQMVFSHILNITQQVQRHSEEVHKGRWTNNKDFCFWDTPLMELRDKKIGLVGLGNTGYTTARVAIGFGMQVYALTSKSHFQLPPEIKKMDLDQLFSECDIISLHCPLTPDTREMVNARRLAMMKPTAILINTGRGPLINEQDLADALNSGKIYAAGVDVLSTEPPCADNPLLTAKNCYITPHIAWATIEARERLMNIAISNLQAYISGKPENVVNK
>NZ_CP041230.1|WP_008022103.1|4031173_4032526_-|MATE-family-efflux-transporter
MQGIKNLTQGPINRQLFNLAMPIMATSFIQMAYSLTDMAWVGRLGSEAVAAIGSVGILTWMSGSISLLNKVGSEVSVGQSIGAQSQEDARSFASHNITIALIISICWGTLLFIFAEPIIRIYELEDHITANAIQYLRIVSTGLPFIFLSAAFTGIYNAAGRSKVPFFISGTGLILNIILDPLFIFGFGLGTNGAAYATWIAEASVFLIFVYQLRCRDALLGGFPFFTRLKKKYTRRIFKLGLPVATLNTLFAFVNMFLCRTASEQGGHIGLMTFTTGGQIEAITWNTSQGFSTALSAFIAQNYAAGRVERVLRAWYTTLWMTGIFGTFCTLLFVFFGNEVFAIFVPEQAAYEAGGVFLRIDGYSQLFMMLEITMQGVFYGIGRTIPPAIISISCNYMRIPLAILFVRMGMGVEGIWWAVCITTVAKGLILLSWFIIIKKKCLSIPSTIKG
>NZ_CP041230.1|WP_004326932.1|4032617_4034003_+|alpha/beta-hydrolase-fold-domain-containing-protein
MKQKFSTIFILLLLFFAGSRVVAQNAPKPFDIEQPSLRVFLPAPELATGRAVVACPGGGYSHLAFEHEGCDWAPYFNKQGIALIVLKYRMPNGDRTLPISDAEAAMKLVRDSADVWNLNPNDIGIMGSSAGGHLASTIATHAKPELRPNFQILFYPVITMDKSYTHRGSHDNLLGKDASAELELEYSNEKQVTKDTPRAFIVYSDDDKVVPPANGVNYYLALNKNNVPSVLHIYPSGGHGWGIREGFLYKNEMLDELTSWLRSFKVPHKDAIRVACIGNSITYGARIKNRDRDSYPAVLSRMLGEAYWVKNFGVSARTLLNKGDHPYMNEKAYQDALAFNPNIVVIKLGTNDSKSFNWKYKADFTKDLQTMVDAFKALPAQPKIYLCYPSKAYQTGDNINDDIISKQIIPMIKKVAKKNNLSVIDLHAAMDGMPQLFPDKIHPNEEGAKVMAKAVYQSLKK
>NZ_CP041230.1|WP_087317920.1|4034196_4036068_+|PAS-domain-containing-sensor-histidine-kinase
MNRLQDFTFFSQLMANANMGWWKANLSTANYECSDFIVELLGLDQTGVISFEDFNKRIQKEEQLSTTVHSYGVYQRPEVVYLLDTVKGSVWVRSKVCFQETDEDGNEIIYGISEVQDGPDMASAYQALQYSERLLSNIFKCLPIGIELYDMDGVLVDLNDKELEMFHIEKKEDVLGINIFDNPIFPKEMKERLKKNEDADFTFRYDFSKVGSYYQNTQKQGTIDLMTKVTTLYNSEHQPINYLLINADKTETTVAYNKIQEFEEFFELVGDYAKVGYAHFNILSGHGYAQKSWYRNVGEADETPLSDIFGTYRHFHPDDRALLIRFLDDARKGLTTKLSKEMRVLREDGTYTWTHVNLLVKKYAPQDRIIEIISINYDITELKRTEEMLVKARDKAEASDRLKSAFLANMSHEIRTPLNAIVGFSSLLTSTENAAEKELYNSLIGHNNKLLLNLINDVIDLSKIESGYLELRPDWVNLTELLDESVAEYAHQVPSGVELLTNYPAHDSLVELDKLRIKQILSNFLSNALKNTTTGHVEVFYEVDHQSVRIGVKDTGRGIPQNMLEKIFERFEKLDSFAQGAGLGLPICKLIVEKMNGRILVDSQLGIGTTFIIELPCRSMLVE
>NZ_CP041230.1|WP_004311592.1|4036335_4038027_+|energy-dependent-translational-throttle-protein-EttA
MAADDKKIIFSMVGVSKAFTPNKNVLKDIYLSFFYGAKIGIIGLNGSGKSTLLKIIAGLEKSFQGEVVFSPGYSVGYLAQEPYLDNTKTVKEVVMEGVQPIVDALTEYEEINQKFGLPEYYEDQDKMDALFARQGELQDIIDATDAWNLDSKLERAMDALRCPPEDQPVENLSGGERRRVALCRLLLQKPDVLLLDEPTNHLDAESIDWLEQHLQQYEGTVIAVTHDRYFLDHVAGWILELDRGEGIPWKGNYSSWLEQKTKRMEMEEKTASKRRKTLERELEWVRMAPKARQAKGKARLNSYDKLLNEDVKEKEEKLEIFIPNGPRLGNKVIEAKHVAKAYGDKLLFDDLNFMLPPNGIVGVIGPNGAGKTTLFRLIMGLETVDKGEFEVGETVKVAYVDQQHRDIDPNKSVYQVISGGNELIRMGGRDVNARAYLSRFNFSGGDQEKLCGVLSGGERNRLHLAMALKEEGNVLLLDEPTNDIDVNTLRALEEGLEDFAGCAVVISHDRWFLDRICTHILAFEGDSNVFYFEGSYSEYEENKMKRLGNEEPKRVRYRKLMTD
>NZ_CP041230.1|WP_004311593.1|4038243_4041489_+|TonB-dependent-receptor
MLKRMRSFLVAAMLMVIATVSAQVTTSSMSGKVTAQDEPIIGATVVAIHEPSGTRYGTVTNISGQFNLQGMRTGGPYKVEVSYVGYQTAIYKGVNLSLGEVYTLNVVLKESSELLDEVIVTAQKTVEKMGTVTNVSERQLTTLPTINRSITDFTKLSPYAGGSNSFAGRDGRYNTITVDGAALNNNFGLSTNNLPGGDAQPISLDAIDEISVNVSPYSVTYSNFTGASINAVTKSGTNELKGTVYTYQKPKNFIGKSINDVDVPNVESYKSSLYGFTLGAPIIKNKLFFFVNGELENSTSPGILWTPSQEEGGSGDNQNHISRTWIKDLKTISDFVKDKYGYDPGSYDKFDDFESKNWKLMARLDWNINKSHKLSLRFNTVKSENDASISSTSSVITKANSNRYGVDAFAFGNSNYGFRNIVTSLSGELNSNFSSSVQNKLLVTYTHIRDSRTTKGDAFPMVDIYKDGKQYMTLGTELFTPFNDVENNVFSVTDNVTINKGNHLITAGATFERQYFMNSYLRAPYGYYRYASMDDFMTGEKPMLYGITYGYNGKDAPGAELTFGMLGAYAQDEYSITPNLKLTYGLRFDLPLYFDDLLGNAAIKEQSFNGTNVDVSEWPKSKLLISPRLGFNWDIKGDRSIVLTGGTGLFTGLLPFVWFTNQPTNAGQMQNMVEFETSELPANFAFNPNYKETLTQNPDMFPSTPGNEVPGAIAYVDPNFKMPQVWRSNVNAEFQLPYGFMLSVGAMYTRDIYNVVQKNMNEKAPSGTYNEQPGRVYWTKNNYYDNPKTKTVIQLTNGDEKGYQYSFNAVLTKKFDFGFTGSFGYTYTMAKDMTANPGSSAASVWQNNVAVNSLNDPGVSYSLFSTPHRLIANASYEVAYANMKTTVSLFYTGYQQGRFSYTYSNDMNGDGNYSDLMYVPASKEEMTFVDIKDKQNNVTYSAVDQQEDFWNYVNNDSYLNDHKGQYVERASSLEPWIHRFDMKIAQDFYAKIGSRKYGIQVSLDMLNIGNLLNSKWGAYRSCGLQSYDNVRLLKTASKVGEPLTYQMNASSREVFQKNSKWDYTASTGSAWQMQLGVKFTF
>NZ_CP041230.1|WP_141409183.1|4041536_4042634_-|endonuclease/exonuclease/phosphatase-family-protein
MKAFYRLFYYISIVLTSILAGVTIAGAFVGNAAPDSFKFMPFIGLILPILLLANLASAIYWTIRWRCWVFIPLIAIFSNWGYMSCVLQSPFFSPASSPMVKMNVYTPGVLTVATYNVDAFNHEHTGYSCKEIASYMRNLQADILCFQEFGINDEFGIDSISAALSNWPYHYIPSSPEGKNLLQLAVFSRYPIKEEHLIIYPDSKNCSLACDIEINGRTIRLFNNHLQTTEVSQNKRKLEKGLRTDDSQRVEHAALGLIDGLHENFRKRAVQADLLKQLIAASPYPTLVCGDFNSLPSSYVYHTVKGDKLQDGFQRSGHGYMYTFKYFKHLLRIDYILHSPELNSTDYFSPDLNYSDHNPVVMRMK
>NZ_CP041230.1|WP_141409184.1|4042679_4045337_-|response-regulator
MNRILHDANNAQRILKLTADTMLLVDRHGVCVDIEPHCDLWFLQEDILLGKNIFELLPEYTRERVMPIFQIVLEEQRSISKNFKLVLKGETFYFKCLMFPYDGMVLCQYRDITQRSNVKRQLEQANLTLRAIQKVAQIGQWTYNTKQNIFHYLGYTGVLCEENVQNLAIEKYVELIVEEDRQSFMEWCRVNEKELNMESISYRVRLNGEIFYMRIQTYLREQRSDGSFNIEGYIQNITDIQHRRNDINTLTHAINNAKESIFAAKPDGTIIFANRRFLYNHGISENEDISQLKIYNVAADMPTQEAWNERCKDVIHGGSSNFVAHHPSKINKGILAYEGTMYNVTNDSGEESYWSFAHDISERIRYEAQIKRLNQIMDTTINNLPAGIVVKEINNDFRYIYRNREAYNRDLYKNDPVGKNDFDFYPPIVAEKKRQEDIQVATTGKGLHWTAEGKDRNGNMIILDKRKIRVDGDELSSPIIVSIEWDITELEMIKRELQSSKEKAEMSDSLKSAFLANMSHEIRTPLNAIVGFSHLIAESDDAEERKTYYNIVNANNERLLQLINEILDLSKIESGTIEFSFGPASLHNLCREVHDAHIFRTPQGVSLVYESSDESLMIETDKNRVFQVISNLIGNAVKFTKEGSISYGYKLVDNQIVFHVTDTGTGIEPEKVGRVFERFAKLNNHAQGTGLGLSICKSIVERLGGKISVNSEFGKGTTFTFTLPYTIANPANVDSSKKENGEGNIAGIASAGKTADSSVDSSANTRHACILVAEDTDSNFDLLEAILGKDHQLIRAHDGMEAVTMFDEVKPDLILMDIKMPNLDGLEATKIIRELSATVPIIAQSAFAYEQDRKAAEEAGCNDFIAKPIADDKLKAMIHKWLLPS
>NZ_CP041230.1|WP_141409185.1|4045407_4046622_-|glycosyltransferase
MNETIALCLEIIFWLALFIVFYTYLGYGIVLYVLVKLKELFVKPVKRSLPASDADLPEVTLFITAFNEEDVIDEKMENSLELDYPADKLHIVWVTDGSNDGTNERLKTRWQGKATIHFQPLRQGKTAAMTRGMTLVDTPLVVFTDANTMVNREAIQEIVLAFQDPKVGCVAGEKRIAVQTKDGAAAGGEGIYWKYESTLKALDARLYSAVGAAGELFAVRRELFEAMEPDTLLDDFILSLRITMKGYTIAYCTNAYAIESGSADMREEEKRKVRIAAGGLQSIWRLRPLLNPFRYGTLSFQYTSHRVLRWSITPFLLFALFPLNIAILLLGGSAIFYGVLLAMQVLFYGLGYWGYYLSTKQIKNKLLFIPYYFLFMNVNVLKGIRYLKKKKGSGAWEKAKRAEK
>NZ_CP041230.1|WP_141409186.1|4046652_4048209_-|spore-coat-protein-CotH
MKRKNNMIFNFVLSKMYIRLACTLSIVLLSSSCIDTKNNLFVDKGNLLSFKFEKKLNPQLAEDIELPIYTSHNKLTWYLDKPIDASNLIASFSTERGKLYINNKEQKDGVTANDFSEIITYTFKGDNGETKDYQVRLLPYTGLPVVIIKTNGEHPLLDRENWLTASFEIKGMNHFEDFKDSIEVKGRGNGTWRFPKKPFNVKLNNKSSILGMPKHKRWSFLANYRDRTLLRNDVTFHIGYIADNLQWTPKSQFAEVIFNGEYQGNFQVCEQIRVDKNRVNVKELTAEDVDEPQITGGYLLEYDSYYDEPNKFRTPINNWPVNIKEPDEKVLNKAQLEYIENYTNTFEALLQAGEYEQVYNEYINVESFIDYWMVQAIVGNKEMGYIYSVYCYKDRNKKLYAGPLWDFDYTTFTTEAENNNKSAVWYKYLFKDPNFKRKVVERFCQLKPQLIGIADYISEKATALSLSEKENSKLWPLSNLDSTIIPNNDEKLTFNEAVSRMRSIYLKRLEWIEQQLNN
>NZ_CP041230.1|WP_008775885.1|4048192_4048969_-|class-I-SAM-dependent-methyltransferase
MIIRNPYDRDDLNIGKKDRVLEVGSGHNPTYRADVIVEQYMETNYHRCGNLKIYPHQDFINANGEVLPFKDKEFDYVICNQVLEHVENPADFIREQCRVSKRGYMETPSLLGEFLFPKKSHKWIILYLDKKLILFEKSRMPGNYENNYGELFLNYLPYQSLTYKLLWLTEGDLMLNRCEWKDNIEFIVNPIDEKYTDFFTKPWSRQMVEQLYPRRSAVKELKKVGSALYYMIKNKVKNKTHRHVPITLEEYMKNEKKK

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Crispr_ID: NZ_CP041230_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041230_3

5127571-5127680

Orphan

Consensus_repeat	Method
TCTGCAAATGGAGAATGACAGGTAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041230_3

>merge|NZ_CP041230|3|5127571-5127680|CRISPRCasFinder
TCTGCAAATGGAGAATGACAGGTAGTCGTATGTGACTTATGTTTTTTCTTTATAGTCTCCATTAATGGATTGTTACTTATACACATCTGCAAATGGAGAATGGACAGGTA

>NZ_CP041230|3|3|5127571-5127680|CRISPRCasFinder
TCTGCAAATGGAGAATGACAGGTAG	TCGTATGTGACTTATGTTTTTTCTTTATAGTCTCCATTAATGGATTGTTACTTATACACA
TCTGCAAATGGAGAATGGACAGGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041230.1\|WP_167509053.1\|5127844_5128021_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041230.1\|WP_122350538.1\|5131478_5131676_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|349760
NZ_CP041230.1\|WP_141409372.1\|5116578_5118564_-\|fimbrillin-family-protein	unknown	unknown	gnl\|CDD\|372499
NZ_CP041230.1\|WP_141409371.1\|5114024_5116526_-\|fimbrillin-family-protein	unknown	unknown	gnl\|CDD\|372499
NZ_CP041230.1\|WP_122350532.1\|5131682_5132339_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041230.1\|WP_122350531.1\|5130020_5130950_+\|amidoligase-enzyme	unknown	unknown	gnl\|CDD\|378827
NZ_CP041230.1\|WP_141409374.1\|5122273_5123254_-\|DUF5119-domain-containing-protein	unknown	unknown	gnl\|CDD\|375016
NZ_CP041230.1\|WP_122350525.1\|5113575_5113860_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041230.1\|WP_141409378.1\|5129085_5129874_+\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|349760
NZ_CP041230.1\|WP_135185671.1\|5118594_5119692_-\|fimbrillin-family-protein	unknown	unknown	gnl\|CDD\|372499
NZ_CP041230.1\|WP_141409376.1\|5124633_5125113_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|273242
NZ_CP041230.1\|WP_087339474.1\|5130946_5131180_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041230.1\|WP_081415331.1\|5133733_5133904_+\|DUF3875-domain-containing-protein	unknown	unknown	gnl\|CDD\|163495
NZ_CP041230.1\|WP_094582421.1\|5125383_5126628_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271185
NZ_CP041230.1\|WP_118290587.1\|5128158_5128575_+\|DUF3408-domain-containing-protein	unknown	unknown	gnl\|CDD\|378750
NZ_CP041230.1\|WP_141409375.1\|5123250_5124582_-\|DUF3575-domain-containing-protein	unknown	unknown	gnl\|CDD\|371897
NZ_CP041230.1\|WP_075964283.1\|5133420_5133771_+\|DUF4133-domain-containing-protein	unknown	unknown	gnl\|CDD\|379272
NZ_CP041230.1\|WP_141409373.1\|5119851_5120979_-\|fimbrillin-family-protein	unknown	unknown	gnl\|CDD\|372499
NZ_CP041230.1\|WP_122350530.1\|5128604_5128991_+\|DUF3408-domain-containing-protein	unknown	unknown	gnl\|CDD\|378750
NZ_CP041230.1\|WP_135185675.1\|5121054_5122197_-\|fimbrillin-family-protein	unknown	unknown	gnl\|CDD\|372499

Protein	Function_ID	Function_description	E-value
NZ_CP041230.1\|WP_122350538.1\|5131478_5131676_+\|ParA-family-protein	gnl\|CDD\|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	1.96841e-05
NZ_CP041230.1\|WP_141409372.1\|5116578_5118564_-\|fimbrillin-family-protein	gnl\|CDD\|372499	pfam13149, Mfa_like_1, Fimbrillin-like. A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.	3.74885e-15
NZ_CP041230.1\|WP_141409371.1\|5114024_5116526_-\|fimbrillin-family-protein	gnl\|CDD\|372499	pfam13149, Mfa_like_1, Fimbrillin-like. A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.	7.02433e-18
NZ_CP041230.1\|WP_122350531.1\|5130020_5130950_+\|amidoligase-enzyme	gnl\|CDD\|378827	pfam12224, Amidoligase_2, Putative amidoligase enzyme. This family of proteins are likely to act as amidoligase enzymes Protein in this family are found in conserved gene neighborhoods encoding a glutamine amidotransferase-like thiol peptidase (in proteobacteria) or an Aig2 family cyclotransferase protein (in firmicutes).	8.9781e-46
NZ_CP041230.1\|WP_141409374.1\|5122273_5123254_-\|DUF5119-domain-containing-protein	gnl\|CDD\|375016	pfam17145, DUF5119, Domain of unknown function (DUF5119). This is a family of uncharacterized Bacteroidia sequences.	1.77639e-66
NZ_CP041230.1\|WP_122350530.1\|5128604_5128991_+\|DUF3408-domain-containing-protein	gnl\|CDD\|378750	pfam11888, DUF3408, Protein of unknown function (DUF3408). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 128 to 160 amino acids in length.	4.50126e-06
NZ_CP041230.1\|WP_141409378.1\|5129085_5129874_+\|P-loop-NTPase	gnl\|CDD\|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	6.75023e-26
NZ_CP041230.1\|WP_135185671.1\|5118594_5119692_-\|fimbrillin-family-protein	gnl\|CDD\|372499	pfam13149, Mfa_like_1, Fimbrillin-like. A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.	7.14634e-13
NZ_CP041230.1\|WP_141409376.1\|5124633_5125113_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|273242	TIGR00738, Putative_HTH-type_transcriptional_regulator, Rrf2 family protein. This model represents a superfamily of probable transcriptional regulators. One member, RRF2 of Desulfovibrio vulgaris is an apparent regulatory protein experimentally (MEDLINE:97293189). The N-terminal region appears related to the DNA-binding biotin repressor region of the BirA bifunctional according to results after three rounds of PSI-BLAST with a fairly high stringency. [Unknown function, General].	2.26721e-24
NZ_CP041230.1\|WP_081415331.1\|5133733_5133904_+\|DUF3875-domain-containing-protein	gnl\|CDD\|163495	TIGR03783, Bac_Flav_CT_G, Bacteroides conjugation system ATPase, TraG family. Members of this family include the predicted ATPase, TraG, encoded by transfer region genes of conjugative transposons of Bacteroides, such as CTnDOT, found on the main chromosome. Members also include TraG homologs borne on plasmids in Bacteroides. The protein family is related to the conjugative transfer system ATPase VirB4. [Cellular processes, DNA transformation].	4.18534e-28
NZ_CP041230.1\|WP_094582421.1\|5125383_5126628_-\|site-specific-integrase	gnl\|CDD\|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.6523e-28
NZ_CP041230.1\|WP_118290587.1\|5128158_5128575_+\|DUF3408-domain-containing-protein	gnl\|CDD\|378750	pfam11888, DUF3408, Protein of unknown function (DUF3408). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 128 to 160 amino acids in length.	9.5934e-19
NZ_CP041230.1\|WP_141409375.1\|5123250_5124582_-\|DUF3575-domain-containing-protein	gnl\|CDD\|371897	pfam12099, DUF3575, Protein of unknown function (DUF3575). This family of proteins are functionally uncharacterized. This family is only found in bacteria. Proteins in this family are typically between 187 to 236 amino acids in length.	4.04692e-47
NZ_CP041230.1\|WP_075964283.1\|5133420_5133771_+\|DUF4133-domain-containing-protein	gnl\|CDD\|379272	pfam13571, DUF4133, Domain of unknown function (DUF4133). Based on Bacteroides thetaiotaomicron gene BT_0094, a putative uncharacterized protein as seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or vs when in culture.	3.41071e-37
NZ_CP041230.1\|WP_141409373.1\|5119851_5120979_-\|fimbrillin-family-protein	gnl\|CDD\|372499	pfam13149, Mfa_like_1, Fimbrillin-like. A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.	2.80812e-15
NZ_CP041230.1\|WP_135185675.1\|5121054_5122197_-\|fimbrillin-family-protein	gnl\|CDD\|372499	pfam13149, Mfa_like_1, Fimbrillin-like. A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.	1.59326e-10

>NZ_CP041230.1|WP_094582421.1|5125383_5126628_-|site-specific-integrase
MMDRKKETLLSPLLDRTLEALKGQRSVRTLENYRSSINKVKEFAGDGWESLTMENITKCWTDKYAAWLEKRHADKPQTADFYLRTFRAVYGHALALSSEGTDGKPFGGHRTGGYFPAKRALRKEEVQRLLSPDLRQTLPENQREALDVLLFILYARGMVFKDVYGLTWRMVTDGHIRYRRSKTDVSIDVEIVPELEEIMERYHLEDSPFVFPFLHEARKGCPGKELPEESALRRINRTARMIGRKVGLSVPLTTYVLRHTWATLMLEDSQPVELISQCMGHTSIRTTQIYLSRISSRKVDTAVDGMYDRMLRKPKHKRKERDIPSGCHRKSESGSPQPMENGNTHPHVSQTPENEKCPFLSKKETFVSCHVNTVIFFAAKVYISYICSKFSSAFFSVSPDISSCLSALYSFHAM
>NZ_CP041230.1|WP_141409376.1|5124633_5125113_-|Rrf2-family-transcriptional-regulator
MLTNPTRYGLIACRYLAWGWHYGVWLNAPEIAERYRINVRALSPALLRLVQAGILYSRVGGPKPGYMLSRDPAEIPMLEVVRALEGTFRMDCCRTVLPNVQCQCEADNCRVCGVFRDILDELRSRLSGVSLEDHAATEEFLPTYWGGKTLQTNKIEYLV
>NZ_CP041230.1|WP_141409375.1|5123250_5124582_-|DUF3575-domain-containing-protein
MKKRFIPSLLLAALLAGNAQAEIVSDSLRTTIYYRTASARLELPYMDNDRHLAALGDSIRSLGSDPAVVLRRILIQASASPDGNTKYNKELARKRGEDLRDYLKDNLSLPDSIFALQPQGEGWSELAEKLGRTDAPWRDKAITIIRDTPEWVVREGKVVDGRKRQLMNLAGGRAWQYMKENLFDSLRSGALVVCEMERIERVKPKPESAQAELKPAPEQAVDNVMNPDDTVDTAGKELETTATLYNKEDETIPQDNTDKEAAEKKPFYMAAKTNLLYDAALVPNVGLEVYLSGGWSVGGDWMYAWWSKDSKHRYWRIYGGELEVRKYFGSKAAEKPLQGHHVGVYAQGLTYDFETGGKGYLSDFNYGFGLEYGYSLPVAKRLNIDFGIGVGYSGGKYKVYDPEDGCYVYKETKKRRWFGPTKAEISLVWLLGHGNENKKGGTK
>NZ_CP041230.1|WP_141409374.1|5122273_5123254_-|DUF5119-domain-containing-protein
MTHIRIYKELRKAIAGCLAAMLLPLLTACEHKDLCYDHPHSANVEVVFDWTEAPDAHPATMSLYLYPEDGSEPMRYEFTKREGGTIIVPEGMYDALCVNSDKETHRIQNKERMETFEVTTGNTRSLRGALTTRSETAPLARGAEEERSVMEPEALWSDHAERLDIGPASGVRRIVLTPKPRVNTCTVEVRNVENLRHVSALSASLTGMAGGWLAGIDELTTEKVTIPFEVHANEEKTQLSGNLTFFGHCPKETGTHKLMIYALMSDGSTYYFEADVTDQLHDPAQDPTHIVIVVDKLPLPKPITGGGGLQPTVKDWEEVHISLPMS
>NZ_CP041230.1|WP_135185675.1|5121054_5122197_-|fimbrillin-family-protein
MMLASCSNDEVVEQAQENAISFRSMMGANTRGVVADVSNLNTLCVTAYQGTNLHFDNVIFQKDGTGFFNSAKPYYWPETGELTFTVLSGNWSGTRDFTSSTEQWMKNVTIDDDISKQEDMTYVSKVRGTKADYGKVGVPLEMKHALVQVQLNAKNTNPNYVYKVKGFRLNNVVSNGDFDFKNEEWNANGKGNIKHKTLEVTYDTPIDLTADAKSIMGTAGNAMVIPCTSLQWIVGGGSFEVPLSADAQPQASTIEGAFFSVLVNIQMKLGATVYPDKVGGYAWVAIPVNYQWAQQHGKKFTYTLDFSNGAGRVDPVDPGTDWDASKDPAKAQPVLGGLIRFGVTVSEWGTDDKNVDLKDPEKFDVTVDGWTDDTKDAPLK
>NZ_CP041230.1|WP_141409373.1|5119851_5120979_-|fimbrillin-family-protein
MNKMIYLCAAAALTLASCSNDETVEVAQQKGISFRAVTGLNTRASEVTTANLSEIQVTAFWDANNNKYDGFTNGEVLYKKDGNGDFNSAIPVYWPGKDQENEKLSFTAFSNNWTGNKTITDKNTISVGSVEINTDVDQQADMVYVTGATGTKVANETAGVPLVLGHALSQIQISAKSDNTVYTYQVKGIRISNVDGEADFDVVTDKWSNNGANDQVYNVTYDNAITLNGTAQTIMKAEGNNLMLLPQAGVDGTGTTTAWDVENDQTNTQKGTYISVLLRITKTADNSNVFPAEGDDTYGWAAVPASFTWVKGNKYVYTLDFTNGAGRVDPVTPGPDVKPQPDGKDPKPGDKILGDPIKFTVTVTPWNPQENNIGM
>NZ_CP041230.1|WP_135185671.1|5118594_5119692_-|fimbrillin-family-protein
MANKAIHVLAAAALILASCSNDDTVQVASGKGIRFRTTVGMNTRALPADLAGLKAAGFSVSAFATAGNEEKYGFRNLLFTHEAGTENDWTSDPLKYWPDDGSELRFVAACPAAADWGGTYEGDKPGELKVTGFSPAADITGQKDLLAGYASGDRNNAAKTEIELRHVLTQVEVRAKNTNATYRYDVKAVRIGSVHSTGDYTFPSETNANGSWTLKDGSYASYATAELTDPIRLTSDAKGLMDDSGTAMLLPQQLTAWDTKDDKENKKNGSYIALLLKITTEAGRQVYPSAEGEYGWAAVSIGGHAESKKNLWQPGDKFVYTLDLSNGAGVMPPDSPDPGEPVLGQPIRFTVTVNNWVIRHQDVNQ
>NZ_CP041230.1|WP_141409372.1|5116578_5118564_-|fimbrillin-family-protein
MTDMNYKNKLMGLSLILLAAFSACTDDVENGGRDSGTDDHRITFAVGTESPDARTRADGSLPDAAGSYETNSVEMQGKLDGKNVYLTAEVSDGLPGDDQPLTRGTQVTGGAQVDEFSVSAAILDANVFEPETLDVMYNVKVAKDNASSTWTTGTPYYWPTGKKLTFFAWYPYNSKNLTIPKDNNVKDTKLFYEIPEQVADQEDFMMANSYEVSETSSVPIFFRHMLTAVKFKTSNNIPACTVKSISLKGVKYKGYHNWQAHNSIILSWNPDADTRDFTLDFPNGKEVAENTETELTGKGETFFMMPQTFGDDSEARLEVTLVMNGVEQTLSAKLKDIMANGSGYSYWVAGTAVTYNISLDQNVELELNKDVFVASGADAVIYVKSNCDWECTLSDPNGITGSAAPALCKPTLKGSTSGVQSDSFDNENAKLTIETIQPTDTETRKGKVKLTFTFPSKPGKTVEKEVTLTSSLMVEYPTGSDIWYKLSQGSMSCHDLMTTDTPTLPDNADFATAIAKVVGANVTYSRELVATRMLNPDDNTQCFTYFGIRRATPDGSTIVVNLSRITLENYGGSTFDEKNFMTWGGTYYPVGSTWTVTKDNYDVKTHVDDMGTDLSVWQSTAMGNWGYDQAYDYSSSTFRYPGYYTIKNNKFGYYSIEKVSN
>NZ_CP041230.1|WP_141409371.1|5114024_5116526_-|fimbrillin-family-protein
MNYRNKLMNLSLIALAVFSACSDEVENGTHPGKGDQRLSFAVSMGGTNAWKPTAGTRAASGLGESTYELKTIEMEGKVNGKTVYLTAEVTDGFPGDNRPMTRGTQISETNKTDMETFALSAYTDATGTPDFMYNETVTLNKDEGRWYPTGTYYWPGKKQLSFYAWFPSAADGMTLTGNTDVGAPVITYTVPDDVKKQQDVMSAAAIGKDNPTADGFATTDLTFNHALTAVKFVAGDDLPNCVVKSIKLDGVRYKGTYTLGTDAWTLTDDTQAFTLRLNKVVAGNGGAITEDGKGETLFMMPQTLSDDAKIEVVLNDGTADFTVGASIGGTKWEMGKTYTYHISNNFVSLVTTNDKFVAFTDETLTDQVAFFLSASATTAGTTGEILAPAGVTVTPTTFASGASNLPVKVTWLKDMGNYVSMEISFAGKKKRILMSRQTPTEGDAYWLYSLPETTSQHLENDIIGLQNASESDWIAMTSSPTYTKDNYSQVIYDNSSKGDIYLQTLSIPSANRFASLLATKEDFDQNVMYCVEQKAFTADFGFKGCERNISRESEKWNIVLNGGHFKDNVTNMKARVVISSDVSDELINDQGRDLTYGEPVSIVVNKTISMAVSATPYVKKRWDNLQNNTANNGTRKVNVQVKNDGMDEWYDCGPDGLMSDRFTWGNNFAIGYNQYHGRGNNWNNGALPIVRDYYEVHQKHPMFGLHRWSIMRDNGDANIMGNALYMIFCSAKQWNGWNNGSIYRNSTSGGWSYIACNQANCITDPENPNYNDVYNGGRFITIGVNGRNWRWSSWQNYPGPLTVWIPVVYTDSHCGLNARPTDGTPIPGTSVNE
>NZ_CP041230.1|WP_122350525.1|5113575_5113860_-|hypothetical-protein
METTKILETEKENKDAVHLYWNEADETWNAYGTSVENALRINPELRALTDKVDLDGMQVTHLKVTTEQFERYGLADYCVAVDDERLKLKIPVHG
>NZ_CP041230.1|WP_167509053.1|5127844_5128021_-|hypothetical-protein
MDGHAAALGRFFLYGGDVRGPLPVEVWKSGQDSVSFSTGPFQSLWVGVGARTCPDTDS
>NZ_CP041230.1|WP_118290587.1|5128158_5128575_+|DUF3408-domain-containing-protein
MDSEKEKNRLSDIVLERVGLTGNLLSDPVSPSPEPAMRMPGHERQVGAGKVTDPEEYKRRFLVPAPKASEWKTAYIDGRLHRRIAMLVRAAGCGSISGFIIRLLELHMEEHREDIAALLGEVYRPWDEDGQPGGTARR
>NZ_CP041230.1|WP_122350530.1|5128604_5128991_+|DUF3408-domain-containing-protein
MTGKNVKDRMGPGGMDADRIREIMGEAPACPRKGRGTSGNDIMRPARKNGPMQPSVYGKEYLHGIAGVQRRSLHIPAALHRKLSILAGASRNGKVTLEGFINHLVSLHLEEYRETVDMILEESLPGRP
>NZ_CP041230.1|WP_141409378.1|5129085_5129874_+|P-loop-NTPase
MMKKEKELLVAIASQKGGVGKSVFTVLLASVLHYRKGMRVAVVDCDSPQHSIALMRERDMESVMKNDDLKVNLYRQYERIRKPAYPVIKSDPEKAVEDLRRYMDEKGETFDIVLFDLPGTLRSEGVVHTVSAMDYIFVPLKADNIVMQSSLQFAKVLEEELIAKGNCNLKGIRLFWNMVDRRGRKDLYDAWNRVIHRMGLRLLSSHIPNTLRYNREADPICKGVFRSTLFPPDPRQEKGSGLPELVEEICPAIGLEESDTDR
>NZ_CP041230.1|WP_122350531.1|5130020_5130950_+|amidoligase-enzyme
MNEQVRSILAQETTKTSKIRQLFLLGVPRAEIARMVTNGNYGFVVNALRRMREREGGLNIHPATAALDYTFNRKFGIEIEAYNCSRERLARELREAGIEVTVESYNHTTRPHWKLVTDSSINGNDTFELVSPILVGEAGLRELEKVCWVLDLCEVKVNESCGLHVHIDAAGFSMATWRNLALSYKHLEPVIDRFMPASRRDNYYCKGLCHVSDEMIRSARTVDELKGRIGNRYHKVNLEAYSRHKTVEFRQHSGTTNFTKMRNWVLFLHKLVTFATREQVPAATALQDIPFLDSEQKLYYKLRTKKLSA
>NZ_CP041230.1|WP_087339474.1|5130946_5131180_+|hypothetical-protein
MNKHMYILADGGRIAASDPSEFVRVLREGSWFDSECTDGEYMVNFSGRYRELHGVTVRTDTPEHFMDDLKKYGYITG
>NZ_CP041230.1|WP_122350538.1|5131478_5131676_+|ParA-family-protein
MKKEPLFIELTGRKGEPGKTFFTVLTAGILHYRRGYNVVVADCDPFQHYIGLTEEKMEHPMTNLM
>NZ_CP041230.1|WP_122350532.1|5131682_5132339_+|hypothetical-protein
MEYAFILLFLYASYLSIEKYVHTGSVLKWRGGQRPASGLPVKEEPAEPREETSEEAVIGRSRYRLWQSPPMDEEYAMSEKRTDTAMKEKKVPVPEFPAPFGRPEEGEVPERYEITGYVERPDPHRARGVTFDDMDLLSRFMTTDHLSEPEQSHARQTLERLEGTDMERILQAGILGSDETLKRYMELYVDSDREPPLLAGKDRESIIRDFDIMDFIPR
>NZ_CP041230.1|WP_075964283.1|5133420_5133771_+|DUF4133-domain-containing-protein
MEYKLNKGVGQDVEFCGLKAQYLYLFAGGLLAVFLVFVILYMAGVNRWFCIALCVVSATGITLGVFRLNRKYGPHGLMKLAAAGYRPYYIINRKRITSLFKRRKYAKHTQSVHPGK
>NZ_CP041230.1|WP_081415331.1|5133733_5133904_+|DUF3875-domain-containing-protein
MRNILKASTLESKFPLLAVEDGCILSKDADVTVGFKVRLPEIFTLTSDDYEAMHGA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP041230_2	2.1\|4030814\|23\|NZ_CP041230\|CRISPRCasFinder	4030814-4030836	23	NZ_CP041230.1	4622427-4622449	2	0.913

1. spacer 2.1|4030814|23|NZ_CP041230|CRISPRCasFinder matches to position: 4622427-4622449, mismatch: 2, identity: 0.913

tgcacctactgccgtaccaatag	CRISPR spacer
tgcacctacagccataccaatag	Protospacer
********* ***.*********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	NZ_LR134423	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 14	2866-2896	7	0.774
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	NC_007501	Lactobacillus phage Lc-Nu, complete genome	30638-30668	7	0.774
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	AY131267	Bacteriophage Lc-Nu, complete genome	30638-30668	7	0.774
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	MH983004	Lactobacillus phage BH1, complete genome	32670-32700	7	0.774
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	NZ_CP004877	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence	52386-52416	7	0.774
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	1065035-1065065	8	0.742
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	67130-67160	8	0.742
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	37911-37941	8	0.742
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	AP013657	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S32-C172, * SEQUENCING IN PROGRESS *	3482-3512	9	0.71
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	MH791414	UNVERIFIED: Aeromonas phage Aswh_1, complete genome	66404-66434	9	0.71
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	AP014421	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S43-C174, * SEQUENCING IN PROGRESS *, 2 ordered pieces	8851-8881	9	0.71
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	AP013664	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S45-C223, * SEQUENCING IN PROGRESS *	5115-5145	9	0.71
NZ_CP041230_1	1.1\|2965316\|31\|NZ_CP041230\|CRISPRCasFinder	2965316-2965346	31	AP013658	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S33-C129, * SEQUENCING IN PROGRESS *	4640-4670	9	0.71

1. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to NZ_LR134423 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 14) position: , mismatch: 7, identity: 0.774

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
ttttatttgattgaaatatttttgcctggat	Protospacer
 **. ************** ****.***.*

2. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.774

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
atcgttttgaatgaaatatacttgtctagca	Protospacer
**. ****** *********.******.. *

3. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.774

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
atcgttttgaatgaaatatacttgtctagca	Protospacer
**. ****** *********.******.. *

4. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to MH983004 (Lactobacillus phage BH1, complete genome) position: , mismatch: 7, identity: 0.774

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
atcgttttgaatgaaatatacttgtctagca	Protospacer
**. ****** *********.******.. *

5. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to NZ_CP004877 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence) position: , mismatch: 7, identity: 0.774

attcttttgattgaaatatatttgtctgaaa----	CRISPR spacer
tttcttttgattttaatatatt----tgaaatatt	Protospacer
 ***********  ********    *****

6. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 8, identity: 0.742

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
tttctttttattgaattatatttgagcgcta	Protospacer
 ******* ****** ********  .*  *

7. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 8, identity: 0.742

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
attcttctgatttaaatatatttttaatatc	Protospacer
******.***** ********** *   *

8. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 8, identity: 0.742

attcttttgattgaaatatatttg----tctgaaa	CRISPR spacer
cttcttttaattcaaatatatttgataattt----	Protospacer
 *******.*** ***********    *.*

9. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to AP013657 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S32-C172, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.71

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
tttctcttgatagaaatatatttgataaacc	Protospacer
 ****.***** ************ . .*

10. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to MH791414 (UNVERIFIED: Aeromonas phage Aswh_1, complete genome) position: , mismatch: 9, identity: 0.71

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
acccttttgattgacatatatttttcctttt	Protospacer
*..*********** ******** **.

11. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to AP014421 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S43-C174, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 9, identity: 0.71

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
tttctcttgatagaaatatatttgataaacc	Protospacer
 ****.***** ************ . .*

12. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to AP013664 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S45-C223, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.71

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
tttctcttgatagaaatatatttgataaacc	Protospacer
 ****.***** ************ . .*

13. spacer 1.1|2965316|31|NZ_CP041230|CRISPRCasFinder matches to AP013658 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C24-MedDCM-OCT-S33-C129, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.71

attcttttgattgaaatatatttgtctgaaa	CRISPR spacer
tttctcttgatagaaatatatttgataaacc	Protospacer
 ****.***** ************ . .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

110387 : 174714

Acanthamoeba_polyphaga_mimivirus(20.0%)

protease,transposase,integrase

attL 108933:108950|attR 172857:172874

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
108933:108950	attL	NA	NA	NA	NA
WP_141408434.1\|110387_111560_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_074559355.1\|112420_115420_+	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
WP_004306509.1\|115436_116990_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_008777222.1\|117218_117791_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008777221.1\|117800_118448_-	NAAT family transporter	NA	NA	NA	NA
WP_141408435.1\|118509_119202_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_004299178.1\|119298_120156_-	hypothetical protein	NA	NA	NA	NA
WP_004299177.1\|120189_120864_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	8.0e-52	47.3
WP_118195688.1\|120876_121554_-	hypothetical protein	NA	NA	NA	NA
WP_004299175.1\|121694_122294_+	thymidine kinase	G3MBK1	Bacillus_virus	3.5e-35	46.7
WP_141408436.1\|122315_123449_+	AI-2E family transporter	NA	NA	NA	NA
WP_141408437.1\|123746_124682_-\|transposase	transposase	NA	NA	NA	NA
WP_008640050.1\|124722_125094_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_141408438.1\|125155_125725_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_141408439.1\|125798_126671_+	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_141408440.1\|126892_130153_+	hypothetical protein	NA	NA	NA	NA
WP_141409578.1\|130373_131825_-	ATP-binding protein	NA	NA	NA	NA
WP_141408441.1\|132180_132585_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_008998991.1\|132630_133020_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_141408442.1\|133353_136440_+	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
WP_141408443.1\|136455_138294_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_087322334.1\|138537_139023_+	flavodoxin	NA	NA	NA	NA
WP_022199146.1\|139162_139522_+	hypothetical protein	NA	NA	NA	NA
WP_164497290.1\|139632_139794_-	hypothetical protein	NA	NA	NA	NA
WP_049703574.1\|139808_140651_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	6.1e-17	37.7
WP_055235665.1\|140647_141178_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.5e-18	42.3
WP_141408444.1\|141674_143768_-	DUF3874 domain-containing protein	I6R9L9	Nonlabens_phage	1.8e-25	28.2
WP_141408445.1\|144115_144766_+	DNA-binding protein	NA	NA	NA	NA
WP_004309081.1\|144979_146059_-	choloylglycine hydrolase family protein	A0A1J0F9I3	Only_Syngen_Nebraska_virus	2.5e-23	28.4
WP_004323539.1\|146227_147940_-	GAF domain-containing protein	A0A1V0SGX0	Hokovirus	1.4e-31	37.5
WP_004309079.1\|148239_148560_-	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_032852847.1\|148713_149286_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_004306433.1\|149360_149726_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_141408446.1\|149985_152118_+	cation:proton antiporter	NA	NA	NA	NA
WP_004299152.1\|152221_152698_+	hypothetical protein	NA	NA	NA	NA
WP_004299151.1\|152752_153598_+	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_004306429.1\|153671_154292_-	hypothetical protein	NA	NA	NA	NA
WP_004309075.1\|154490_154907_+	DUF3788 domain-containing protein	NA	NA	NA	NA
WP_004309074.1\|154903_156034_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004306423.1\|156065_156536_+	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_004315537.1\|156680_157586_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_008770674.1\|158171_159584_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_141408447.1\|159575_160772_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_004299141.1\|161021_161240_+	hypothetical protein	NA	NA	NA	NA
WP_008025240.1\|161458_162562_-	Fic family protein	D7RWK9	Brochothrix_phage	3.2e-13	24.1
WP_004315243.1\|162660_164034_-	MATE family efflux transporter	NA	NA	NA	NA
WP_004315244.1\|164127_164862_-	lipoprotein	NA	NA	NA	NA
WP_004315245.1\|164946_165474_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004315246.1\|165485_166112_-	CatB-related O-acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	2.7e-22	40.0
WP_004315247.1\|166184_166655_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_004315248.1\|166832_168119_+	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	A0A0B5JD48	Pandoravirus	1.2e-16	28.2
WP_004306417.1\|168187_168427_+	hypothetical protein	NA	NA	NA	NA
WP_004315249.1\|168533_169439_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_004315250.1\|169592_172133_-\|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_008025245.1\|172137_174714_-\|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
172857:172874	attR	NA	NA	NA	NA

DBSCAN-SWA_2

389730 : 434140

Tetraselmis_virus(33.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004315537.1\|389730_390636_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_008026192.1\|391124_392447_+	ATP-binding protein	NA	NA	NA	NA
WP_008022065.1\|392590_393949_+\|transposase	transposase	NA	NA	NA	NA
WP_008026191.1\|394239_396084_-	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase	NA	NA	NA	NA
WP_004296231.1\|396231_396741_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-27	45.8
WP_008026188.1\|396793_397174_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_004316578.1\|397203_397875_-	hypothetical protein	NA	NA	NA	NA
WP_008644971.1\|397923_399408_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_055235815.1\|399546_400920_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_141408494.1\|401155_402466_+	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_008026182.1\|402470_402872_-	hypothetical protein	NA	NA	NA	NA
WP_008016291.1\|403092_404766_-	nucleoside kinase	NA	NA	NA	NA
WP_008644967.1\|404848_406546_+	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_004306971.1\|406704_406869_-	rubredoxin	NA	NA	NA	NA
WP_087323313.1\|407092_408268_+	two-component sensor histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	1.2e-23	30.6
WP_015531659.1\|408358_411064_+	calcium-translocating P-type ATPase, PMCA-type	A0A1J0FA34	Only_Syngen_Nebraska_virus	7.8e-114	34.6
WP_008026174.1\|411053_411677_+	HAD family phosphatase	NA	NA	NA	NA
WP_008026172.1\|411687_412668_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_008026168.1\|412807_413587_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004316653.1\|413602_414028_-	SufE family protein	NA	NA	NA	NA
WP_004316652.1\|414050_415046_-	M28 family peptidase	NA	NA	NA	NA
WP_015531658.1\|415116_416025_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_008026160.1\|416242_417202_+	phosphate butyryltransferase	NA	NA	NA	NA
WP_008018575.1\|417227_418289_+	butyrate kinase	NA	NA	NA	NA
WP_008022065.1\|418602_419961_-\|transposase	transposase	NA	NA	NA	NA
WP_008018576.1\|420147_421905_-	ATP-binding protein	NA	NA	NA	NA
WP_004316645.1\|421934_422408_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_008644935.1\|422627_422891_+	hypothetical protein	NA	NA	NA	NA
WP_004311937.1\|423387_425514_-	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_141408495.1\|425710_426862_+	DUF4369 domain-containing protein	NA	NA	NA	NA
WP_032811363.1\|427043_427508_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_141408496.1\|427559_427952_+	HIT domain-containing protein	NA	NA	NA	NA
WP_141408497.1\|428088_428988_-	EamA family transporter	NA	NA	NA	NA
WP_120144590.1\|428991_430308_-	MFS transporter	NA	NA	NA	NA
WP_008022065.1\|431265_432624_+\|transposase	transposase	NA	NA	NA	NA
WP_004297445.1\|433138_434140_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2133186 : 2226274

Trichoplusia_ni_ascovirus(11.11%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008025715.1\|2133186_2134122_-\|transposase	DDE transposase	NA	NA	NA	NA
WP_008640050.1\|2134162_2134534_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_008024540.1\|2135199_2136870_+	hypothetical protein	NA	NA	NA	NA
WP_141408833.1\|2137093_2140081_+	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
WP_008024544.1\|2140093_2141665_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_008997879.1\|2141678_2142842_+	SusF/SusE family outer membrane protein	NA	NA	NA	NA
WP_087318191.1\|2142858_2144421_+	SusF/SusE family outer membrane protein	NA	NA	NA	NA
WP_141408834.1\|2144449_2145814_+	hypothetical protein	NA	NA	NA	NA
WP_008024552.1\|2145826_2147239_+	glycoside hydrolase	NA	NA	NA	NA
WP_008997877.1\|2147291_2148737_+	sialate O-acetylesterase	NA	NA	NA	NA
WP_141408835.1\|2148781_2150986_+	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_008024558.1\|2151387_2151624_-	hypothetical protein	NA	NA	NA	NA
WP_141408836.1\|2151777_2152368_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_004299904.1\|2152384_2153131_+	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	2.1e-21	33.6
WP_004299905.1\|2153140_2153812_+	RNA pseudouridine synthase	NA	NA	NA	NA
WP_008771523.1\|2153856_2155164_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_074708887.1\|2155465_2157736_+	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_167509087.1\|2158037_2159198_-	hypothetical protein	NA	NA	NA	NA
WP_004304956.1\|2159694_2161140_-	glycoside hydrolase family 125 protein	NA	NA	NA	NA
WP_061448197.1\|2161199_2162357_-	hydrolase	NA	NA	NA	NA
WP_061448198.1\|2162411_2163362_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_073343648.1\|2163415_2165698_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_141408837.1\|2165908_2169949_+	response regulator	NA	NA	NA	NA
WP_122136137.1\|2170137_2172111_+	LamG domain-containing protein	NA	NA	NA	NA
WP_008018369.1\|2172129_2173377_+	hypothetical protein	NA	NA	NA	NA
WP_004313036.1\|2173391_2174783_+	glycosyl hydrolase family 76	NA	NA	NA	NA
WP_004299917.1\|2174819_2178065_+	TonB-dependent receptor	NA	NA	NA	NA
WP_004299918.1\|2178078_2180007_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_004310443.1\|2180043_2181615_+	LamG domain-containing protein	A0A0A7RU14	Clostridium_phage	3.1e-06	43.8
WP_117684362.1\|2181734_2182001_-	hypothetical protein	NA	NA	NA	NA
WP_117684363.1\|2182275_2183832_-	sulfatase	A0A2P0VMN7	Tetraselmis_virus	1.0e-17	24.9
WP_141408838.1\|2184047_2185421_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_141408839.1\|2185508_2186348_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_141408840.1\|2186353_2187592_+	insulinase family protein	NA	NA	NA	NA
WP_049701794.1\|2187676_2189035_+	MATE family efflux transporter	NA	NA	NA	NA
WP_141408841.1\|2189069_2191388_+	response regulator	A0A1V0SGX0	Hokovirus	5.4e-31	27.0
WP_167509089.1\|2191502_2196014_+	translocation/assembly module TamB	NA	NA	NA	NA
WP_009040283.1\|2196016_2198359_+	BamA/TamA family outer membrane protein	NA	NA	NA	NA
WP_004299937.1\|2198883_2199795_+	hypothetical protein	NA	NA	NA	NA
WP_141408842.1\|2199937_2201893_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.9e-54	29.0
WP_004299939.1\|2202102_2204139_+	M13 family metallopeptidase	E3T4I7	Cafeteria_roenbergensis_virus	2.2e-92	33.0
WP_004299940.1\|2204290_2205814_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	S4VT61	Pandoravirus	6.6e-54	39.6
WP_004299941.1\|2205829_2206852_+	rod shape-determining protein	NA	NA	NA	NA
WP_004299942.1\|2206859_2207705_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004314401.1\|2207701_2208199_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004324644.1\|2208201_2210064_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_008024621.1\|2210044_2211502_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_004319780.1\|2211594_2211951_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_004312010.1\|2211954_2212320_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_004312011.1\|2212395_2214069_+\|transposase	IS66-like element ISBf10 family transposase	A0A218MNE7	uncultured_virus	2.1e-37	28.9
WP_141408843.1\|2214034_2214925_-	gliding motility lipoprotein GldH	NA	NA	NA	NA
WP_004314398.1\|2214902_2216402_-	hypothetical protein	NA	NA	NA	NA
WP_008024625.1\|2216417_2217542_-	DNA polymerase III subunit	NA	NA	NA	NA
WP_004304907.1\|2217543_2218497_-	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_004304906.1\|2218683_2219196_-	ferritin	NA	NA	NA	NA
WP_118219981.1\|2219441_2221538_-	DUF3874 domain-containing protein	I6R9Q6	Nonlabens_phage	2.4e-22	28.1
WP_004304904.1\|2221675_2222113_+	hypothetical protein	NA	NA	NA	NA
WP_141408845.1\|2222629_2224297_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_004315537.1\|2225368_2226274_+\|transposase	IS982 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2427870 : 2494638

Klosneuvirus(11.11%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004315537.1\|2427870_2428776_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_009041301.1\|2428956_2430558_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_008642045.1\|2430652_2431003_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_009041302.1\|2430990_2431380_-	hypothetical protein	NA	NA	NA	NA
WP_141408879.1\|2432199_2434470_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_004315134.1\|2434574_2436881_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_167509093.1\|2436925_2437933_-	DUF4974 domain-containing protein	NA	NA	NA	NA
WP_004310994.1\|2437967_2438525_-	RNA polymerase sigma-70 factor	NA	NA	NA	NA
WP_141409606.1\|2438552_2440790_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_004315136.1\|2441313_2443932_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.5e-98	42.5
WP_004305395.1\|2444103_2445072_+	M23 family metallopeptidase	A8ATH6	Listeria_phage	4.4e-19	40.1
WP_004301384.1\|2445092_2445437_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_009039031.1\|2445473_2447714_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.2e-11	37.0
WP_004315140.1\|2447786_2449082_-	lytic transglycosylase domain-containing protein	A0A0S2SXN2	Bacillus_phage	5.7e-14	42.5
WP_004315141.1\|2449115_2450003_-	hypothetical protein	NA	NA	NA	NA
WP_004301392.1\|2450003_2450894_-	ParB/RepB/Spo0J family partition protein	S5VSZ7	Leptospira_phage	3.3e-13	36.3
WP_004301394.1\|2450909_2451674_-	ParA family protein	Q8JL10	Natrialba_phage	7.5e-22	34.3
WP_008020629.1\|2452029_2452797_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	4.7e-32	33.1
WP_009039034.1\|2452889_2454026_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_141408880.1\|2454120_2454921_+	hypothetical protein	NA	NA	NA	NA
WP_008642078.1\|2455027_2455876_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_008642079.1\|2455892_2458046_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	G9E4U6	Ostreococcus_lucimarinus_virus	1.0e-108	42.6
WP_004310984.1\|2458055_2458415_-	ribosome silencing factor	NA	NA	NA	NA
WP_008025715.1\|2458887_2459823_-\|transposase	DDE transposase	NA	NA	NA	NA
WP_008640050.1\|2459863_2460235_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_004301408.1\|2460539_2462393_-	DUF349 domain-containing protein	NA	NA	NA	NA
WP_004312092.1\|2462478_2463819_-	magnesium transporter	NA	NA	NA	NA
WP_004312093.1\|2463880_2464681_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_004315816.1\|2464797_2465784_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_141408881.1\|2465905_2467363_+	beta-Ala-His dipeptidase	NA	NA	NA	NA
WP_087321590.1\|2468739_2470407_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_167509095.1\|2470760_2476505_+	alpha-2-macroglobulin	NA	NA	NA	NA
WP_004301426.1\|2476730_2477798_+	DUF1573 domain-containing protein	NA	NA	NA	NA
WP_004320987.1\|2477809_2478901_+	methylmalonyl Co-A mutase-associated GTPase MeaB	NA	NA	NA	NA
WP_004315635.1\|2478992_2479910_-	DMT family transporter	NA	NA	NA	NA
WP_004312099.1\|2480032_2480896_+	ATP-binding protein	NA	NA	NA	NA
WP_004315637.1\|2480918_2481947_+	DUF4435 domain-containing protein	NA	NA	NA	NA
WP_032849615.1\|2482065_2483325_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_004315639.1\|2483359_2484256_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_117683340.1\|2484282_2485848_-	ATP-binding protein	NA	NA	NA	NA
WP_141408882.1\|2489051_2490260_+	hypothetical protein	NA	NA	NA	NA
WP_141408883.1\|2490452_2493263_+	PAS domain-containing protein	A0A1V0SGX0	Hokovirus	3.8e-31	36.4
WP_008771523.1\|2493330_2494638_-\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

3196968 : 3258527

Erysipelothrix_phage(12.5%)

tRNA,transposase,integrase

attL 3202019:3202033|attR 3210482:3210496

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117860485.1\|3196968_3197772_-\|integrase	tyrosine-type recombinase/integrase	A0A0H4TI16	Erysipelothrix_phage	3.4e-09	24.1
WP_119979479.1\|3197676_3198303_+	type I restriction endonuclease subunit S	NA	NA	NA	NA
WP_167509115.1\|3198297_3199434_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_119979480.1\|3199533_3199938_-	hypothetical protein	NA	NA	NA	NA
WP_117860476.1\|3199972_3200914_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_117860475.1\|3200903_3201212_-	MobC family plasmid mobilization relaxosome protein	NA	NA	NA	NA
WP_117860474.1\|3201351_3202431_-	hypothetical protein	NA	NA	NA	NA
3202019:3202033	attL	NA	NA	NA	NA
WP_117860483.1\|3202509_3203886_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_015532562.1\|3203894_3204263_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015532563.1\|3204610_3205690_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_117860473.1\|3205692_3206817_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_015532565.1\|3207055_3207943_-	hypothetical protein	NA	NA	NA	NA
WP_015532566.1\|3208125_3208485_-	hypothetical protein	NA	NA	NA	NA
WP_117860472.1\|3208493_3209600_-\|integrase	site-specific integrase	A0A1B0WMK0	Flavobacterium_phage	1.1e-05	25.6
WP_117860471.1\|3209684_3210587_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
3210482:3210496	attR	NA	NA	NA	NA
WP_141409019.1\|3210836_3212234_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_141409020.1\|3212368_3214276_+	response regulator	A0A1V0SGX0	Hokovirus	3.9e-35	30.9
WP_167509172.1\|3214367_3215018_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004302019.1\|3215135_3216014_-	nucleoside phosphorylase	NA	NA	NA	NA
WP_004304885.1\|3216170_3217172_-	flotillin-like protein FloA	NA	NA	NA	NA
WP_009040378.1\|3217194_3217665_-	hypothetical protein	NA	NA	NA	NA
WP_141409021.1\|3217681_3219103_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_009040380.1\|3219286_3220033_+	adenine nucleotide alpha hydrolase family protein	A0A0U2S5Z2	Escherichia_phage	4.1e-25	32.5
WP_004302024.1\|3220048_3220420_+	DMT family protein	NA	NA	NA	NA
WP_004309770.1\|3220496_3221510_-	FAD:protein FMN transferase	NA	NA	NA	NA
WP_004302038.1\|3221540_3222122_-	manganese efflux pump	NA	NA	NA	NA
WP_004309771.1\|3222128_3222878_-	hypothetical protein	NA	NA	NA	NA
WP_004309772.1\|3222861_3223446_-	hypothetical protein	NA	NA	NA	NA
WP_004309773.1\|3223467_3224418_-	glycosyltransferase family 2 protein	F1C5B0	Cronobacter_phage	9.3e-22	30.6
WP_015532571.1\|3224450_3225008_-	DUF4199 domain-containing protein	NA	NA	NA	NA
WP_008640050.1\|3225547_3225919_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_008025715.1\|3225959_3226895_+\|transposase	DDE transposase	NA	NA	NA	NA
WP_004309775.1\|3227110_3227584_-	hypothetical protein	NA	NA	NA	NA
WP_141409022.1\|3227986_3229267_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.3e-172	72.9
WP_008644437.1\|3229446_3230109_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004309778.1\|3230139_3230517_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_004309779.1\|3230874_3233034_+	glycoside hydrolase family 97 protein	NA	NA	NA	NA
WP_004302052.1\|3233198_3234608_+	amidophosphoribosyltransferase	NA	NA	NA	NA
WP_141409023.1\|3234760_3235984_+	peptidase T	NA	NA	NA	NA
WP_120079044.1\|3236045_3237131_+	glycine cleavage system aminomethyltransferase GcvT	NA	NA	NA	NA
WP_008644441.1\|3237281_3239555_+	sodium:proton antiporter	NA	NA	NA	NA
WP_120079045.1\|3239604_3240030_+	HIT family protein	NA	NA	NA	NA
WP_008021285.1\|3240301_3240724_-	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_032855967.1\|3240838_3241405_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_004309786.1\|3241541_3242132_-	50S ribosomal protein L25/general stress protein Ctc	NA	NA	NA	NA
WP_004309787.1\|3242269_3242671_-	PUR family DNA/RNA-binding protein	NA	NA	NA	NA
WP_008021289.1\|3242839_3243766_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_004302063.1\|3243805_3244129_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_004313972.1\|3244150_3245164_+	YbbR-like domain-containing protein	NA	NA	NA	NA
WP_117684308.1\|3245153_3245768_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_004313967.1\|3245792_3246221_+	DUF5606 domain-containg protein	NA	NA	NA	NA
WP_004313964.1\|3246840_3249429_-	ATP-dependent chaperone ClpB	A0A223W0B1	Agrobacterium_phage	7.4e-122	34.5
WP_141409024.1\|3249662_3251291_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	7.4e-19	28.0
WP_004313961.1\|3251461_3252046_+	hypothetical protein	NA	NA	NA	NA
WP_118194702.1\|3252106_3253003_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_008021301.1\|3253003_3254725_-	ATP-binding protein	NA	NA	NA	NA
WP_141409025.1\|3255017_3256685_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_087321590.1\|3256859_3258527_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

4584402 : 4599265

unidentified_phage(81.82%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141409289.1\|4584402_4585758_+	hypothetical protein	H7BUJ9	unidentified_phage	1.1e-262	99.8
WP_115484561.1\|4585759_4586803_+	hypothetical protein	H7BUJ8	unidentified_phage	9.7e-198	98.3
WP_141409290.1\|4586799_4588509_+	PHP domain-containing protein	H7BUJ7	unidentified_phage	7.5e-264	97.8
WP_108912208.1\|4588511_4588709_+	hypothetical protein	NA	NA	NA	NA
WP_008768550.1\|4588715_4590017_+	AAA family ATPase	H7BUJ6	unidentified_phage	9.4e-251	99.8
WP_141409291.1\|4590023_4592219_+	DNA polymerase III subunit alpha	H7BUJ5	unidentified_phage	0.0e+00	99.6
WP_008647879.1\|4592215_4592743_+	ATP-binding cassette domain-containing protein	A0A0E3X9J6	Bacillus_phage	1.6e-10	39.7
WP_008647882.1\|4592744_4593518_+	hypothetical protein	H7BUJ3	unidentified_phage	1.3e-143	100.0
WP_008647883.1\|4593521_4593803_+	hypothetical protein	NA	NA	NA	NA
WP_008647884.1\|4593875_4594361_+	hypothetical protein	H7BUJ2	unidentified_phage	6.2e-14	100.0
WP_008647885.1\|4594369_4594573_+	hypothetical protein	NA	NA	NA	NA
WP_141409292.1\|4594574_4595255_+	hypothetical protein	NA	NA	NA	NA
WP_032846307.1\|4595259_4595688_+	hypothetical protein	A0A2I7RVN5	Vibrio_phage	1.9e-06	27.8
WP_008647889.1\|4595684_4596200_+	hypothetical protein	NA	NA	NA	NA
WP_008768544.1\|4596249_4596576_+	hypothetical protein	NA	NA	NA	NA
WP_008647899.1\|4596668_4598246_+\|portal	phage portal protein	H7BUJ0	unidentified_phage	0.0e+00	100.0
WP_141409293.1\|4598248_4599265_+	hypothetical protein	H7BUI9	unidentified_phage	6.3e-194	99.1

DBSCAN-SWA_7

4680252 : 4693648

unidentified_phage(85.71%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004325867.1\|4680252_4681974_-	hypothetical protein	H7BUT1	unidentified_phage	0.0e+00	98.3
WP_004325866.1\|4681933_4682614_-	hypothetical protein	NA	NA	NA	NA
WP_004325865.1\|4682594_4682939_-	hypothetical protein	NA	NA	NA	NA
WP_004325864.1\|4682913_4683588_-	site-specific DNA-methyltransferase	H9YP98	environmental_Halophage	2.0e-26	33.6
WP_004325863.1\|4683744_4684692_-	hypothetical protein	H7BUS8	unidentified_phage	2.3e-161	96.2
WP_004325862.1\|4684806_4685613_-	hypothetical protein	H7BUS7	unidentified_phage	5.4e-148	97.8
WP_004325861.1\|4685671_4687876_-	hypothetical protein	H7BUS6	unidentified_phage	0.0e+00	97.8
WP_004303397.1\|4687900_4688767_-\|protease	protease	H7BUS5	unidentified_phage	2.9e-163	97.2
WP_017142804.1\|4688828_4689230_-	hypothetical protein	NA	NA	NA	NA
WP_004303399.1\|4689350_4689839_-	hypothetical protein	NA	NA	NA	NA
WP_004303400.1\|4690433_4690748_-	hypothetical protein	NA	NA	NA	NA
WP_004325859.1\|4690744_4693648_-	hypothetical protein	H7BUS3	unidentified_phage	0.0e+00	99.2

DBSCAN-SWA_8

5763118 : 5818195

uncultured_Caudovirales_phage(20.0%)

integrase,transposase,tRNA

attL 5805704:5805763|attR 5813809:5813928

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008022065.1\|5763118_5764477_-\|transposase	transposase	NA	NA	NA	NA
WP_141409439.1\|5764788_5765733_-	nitronate monooxygenase	NA	NA	NA	NA
WP_004314511.1\|5765901_5766627_-	DUF4858 domain-containing protein	NA	NA	NA	NA
WP_008644616.1\|5766838_5767363_-	DUF4943 family protein	NA	NA	NA	NA
WP_141409440.1\|5767374_5768424_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_004300758.1\|5768407_5768959_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_004314515.1\|5769184_5770033_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_008025787.1\|5770025_5770418_-	DUF4783 domain-containing protein	NA	NA	NA	NA
WP_004314516.1\|5770545_5771019_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_008644609.1\|5771038_5771638_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_004311349.1\|5771592_5771892_-	hypothetical protein	NA	NA	NA	NA
WP_004311350.1\|5771969_5772611_-	HD domain-containing protein	NA	NA	NA	NA
WP_008644607.1\|5772648_5773104_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	3.1e-47	64.4
WP_004311351.1\|5773683_5774343_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.1e-57	50.7
WP_004311352.1\|5774351_5775032_-	queuosine precursor transporter	A0A1W7AG82	Streptococcus_virus	1.4e-32	37.1
WP_008644602.1\|5775266_5776271_+	virulence RhuM family protein	Q9JMN3	Wolbachia_phage	4.1e-60	42.1
WP_032851668.1\|5776500_5777007_-	RNA polymerase sigma factor	A0A0F6TH34	Sinorhizobium_phage	9.4e-13	30.6
WP_008644596.1\|5777170_5778460_+	hypothetical protein	NA	NA	NA	NA
WP_074705501.1\|5778577_5779987_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_074705499.1\|5780197_5781199_+	2-hydroxyacid dehydrogenase	M1I636	Acanthocystis_turfacea_Chlorella_virus	2.0e-59	44.4
WP_004314524.1\|5781262_5781967_+	pirin family protein	NA	NA	NA	NA
WP_074705496.1\|5782010_5782658_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_009041224.1\|5782724_5783456_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_120144337.1\|5783469_5784615_+	DUF4468 domain-containing protein	NA	NA	NA	NA
WP_004304308.1\|5784629_5785007_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_008774710.1\|5785318_5785786_-	hypothetical protein	NA	NA	NA	NA
WP_004300779.1\|5785790_5785976_-	hypothetical protein	NA	NA	NA	NA
WP_120144339.1\|5786071_5786803_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_141409441.1\|5786948_5787551_-	redoxin family protein	NA	NA	NA	NA
WP_087323662.1\|5787770_5788658_-	DMT family transporter	NA	NA	NA	NA
WP_141409442.1\|5788815_5789349_-	hypothetical protein	NA	NA	NA	NA
WP_141408677.1\|5789561_5790497_-\|transposase	transposase	NA	NA	NA	NA
WP_008640050.1\|5790537_5790909_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_004312937.1\|5791175_5791391_-	hypothetical protein	NA	NA	NA	NA
WP_008774741.1\|5791387_5793874_-	ferrous iron transport protein B	NA	NA	NA	NA
WP_141409443.1\|5794019_5795300_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_074705482.1\|5795284_5796121_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_015532994.1\|5796357_5798616_+	transcription termination factor Rho	NA	NA	NA	NA
WP_162613011.1\|5798902_5800369_+	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_008025832.1\|5800641_5801964_+	MATE family efflux transporter	NA	NA	NA	NA
WP_004312925.1\|5802068_5803391_+	signal recognition particle protein	NA	NA	NA	NA
WP_004312924.1\|5803597_5804479_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.1e-28	31.7
WP_141409444.1\|5804475_5805630_+	CapA family protein	A0A2H4JG01	uncultured_Caudovirales_phage	2.7e-39	28.9
5805704:5805763	attL	NA	NA	NA	NA
WP_141409445.1\|5805910_5807185_+\|integrase	site-specific integrase	H7BVW5	unidentified_phage	1.1e-70	54.5
WP_141409446.1\|5807572_5808100_+	hypothetical protein	NA	NA	NA	NA
WP_141409447.1\|5808260_5810201_+	hypothetical protein	NA	NA	NA	NA
WP_141409448.1\|5810891_5811908_+	DUF3871 family protein	NA	NA	NA	NA
WP_032812064.1\|5812945_5813317_+	hypothetical protein	NA	NA	NA	NA
WP_008641868.1\|5814415_5814790_+	hypothetical protein	NA	NA	NA	NA
5813809:5813928	attR	NA	NA	NA	NA
WP_004316244.1\|5814783_5815116_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_141409449.1\|5815223_5816993_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.8e-33	28.8
WP_004313273.1\|5817031_5818195_-\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

5919187 : 5988913

Tupanvirus(12.5%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004300862.1\|5919187_5920207_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.0e-26	33.2
WP_141409471.1\|5920355_5921555_+	MFS transporter	NA	NA	NA	NA
WP_008644887.1\|5921551_5922229_+	endonuclease III	NA	NA	NA	NA
WP_004300866.1\|5922322_5923582_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_118195832.1\|5923699_5924677_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004314227.1\|5924701_5925745_+	hypothetical protein	NA	NA	NA	NA
WP_004314226.1\|5925875_5927060_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_118195830.1\|5927070_5929275_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_087322459.1\|5929417_5929999_-	septum formation protein Maf	NA	NA	NA	NA
WP_008026011.1\|5930069_5930591_-	HAD-IIIA family hydrolase	NA	NA	NA	NA
WP_141409472.1\|5930571_5931366_-	DUF2520 domain-containing protein	NA	NA	NA	NA
WP_008026007.1\|5931373_5931709_-	hypothetical protein	NA	NA	NA	NA
WP_008771322.1\|5931711_5932248_-	NAD(P)H nitroreductase	A0A1V0E011	Clostridioides_phage	3.9e-17	32.8
WP_008026002.1\|5932428_5932653_+	hypothetical protein	NA	NA	NA	NA
WP_141409473.1\|5932742_5933285_-	carbonic anhydrase	NA	NA	NA	NA
WP_141409474.1\|5933435_5934434_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004311398.1\|5934609_5935014_+	methylmalonyl-CoA epimerase	NA	NA	NA	NA
WP_004300890.1\|5935042_5936596_+	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_008644873.1\|5936627_5937548_+	hypothetical protein	NA	NA	NA	NA
WP_004300895.1\|5937572_5938004_+	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_004300899.1\|5938005_5939166_+	sodium ion-translocating decarboxylase subunit beta	NA	NA	NA	NA
WP_141409475.1\|5939460_5940801_+	hypothetical protein	NA	NA	NA	NA
WP_008644872.1\|5940885_5941890_-	class II fructose-1,6-bisphosphate aldolase	NA	NA	NA	NA
WP_004300906.1\|5942323_5942578_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_004300908.1\|5942658_5943873_-	ATP-binding protein	NA	NA	NA	NA
WP_004300910.1\|5944066_5944474_+	hypothetical protein	NA	NA	NA	NA
WP_141409476.1\|5945206_5945635_+	hypothetical protein	NA	NA	NA	NA
WP_008777519.1\|5946141_5947755_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	6.4e-47	31.6
WP_004323560.1\|5947824_5948334_-	hypothetical protein	NA	NA	NA	NA
WP_004304417.1\|5949021_5950077_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_141409477.1\|5950143_5953176_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_008644859.1\|5953224_5954496_+	TolC family protein	NA	NA	NA	NA
WP_004304421.1\|5954666_5954930_-	hypothetical protein	NA	NA	NA	NA
WP_004300937.1\|5955033_5956269_-	sodium ion-translocating decarboxylase subunit beta	NA	NA	NA	NA
WP_004314195.1\|5956268_5958104_-	oxaloacetate decarboxylase	NA	NA	NA	NA
WP_004300941.1\|5958130_5958391_-	OadG family protein	NA	NA	NA	NA
WP_008640050.1\|5958716_5959088_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_008025715.1\|5959128_5960064_+\|transposase	DDE transposase	NA	NA	NA	NA
WP_141409478.1\|5960826_5961666_-	histidine kinase	NA	NA	NA	NA
WP_008771523.1\|5961951_5963259_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_141409479.1\|5963778_5965353_-	peptide chain release factor 3	A0A2K5B2A5	Erysipelothrix_phage	4.2e-35	26.5
WP_141409480.1\|5965436_5966303_-	dTDP-4-dehydrorhamnose reductase	A0A1D7XFA3	Escherichia_phage	2.5e-34	38.0
WP_008651846.1\|5966303_5966849_-	DUF4924 family protein	NA	NA	NA	NA
WP_004314184.1\|5966860_5967514_-	LysE family transporter	NA	NA	NA	NA
WP_118418171.1\|5967773_5971478_+	phosphoribosylformylglycinamidine synthase	A0A0S0BVK5	Lymphocryptovirus	5.2e-36	25.8
WP_141409481.1\|5971746_5975757_+	response regulator	W8CYM9	Bacillus_phage	5.9e-09	35.9
WP_004300957.1\|5975753_5976296_+	chromate transporter	NA	NA	NA	NA
WP_004300958.1\|5976421_5976970_+	chromate transporter	NA	NA	NA	NA
WP_008022065.1\|5977155_5978514_+\|transposase	transposase	NA	NA	NA	NA
WP_032810880.1\|5978800_5980309_-	family 10 glycosylhydrolase	NA	NA	NA	NA
WP_141409482.1\|5980403_5983175_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.1e-223	44.5
WP_087323871.1\|5983272_5983758_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_004300962.1\|5983762_5983993_-	hypothetical protein	NA	NA	NA	NA
WP_118407255.1\|5983989_5985420_-	carbon starvation protein A	NA	NA	NA	NA
WP_141409483.1\|5985529_5986996_+	family 10 glycosylhydrolase	NA	NA	NA	NA
WP_004297445.1\|5987911_5988913_+\|transposase	IS110 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP041230.1|WP_004291533.1|3570231_3570648_+|hypothetical-protein

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Acr_ID: NZ_CP041230.1|WP_120489990.1|3761593_3762019_+|PcfK-like-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP041230.1|WP_004291533.1|3570231_3570648_+|hypothetical-protein

3570231_3570648_+

138 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|40	0.5571428571428572	0.9855072463768116	0.9929078014184397

NZ_CP041230.1|WP_120489990.1|3761593_3762019_+|PcfK-like-protein

3761593_3762019_+

141 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|40	0.5285714285714286	0.9929078014184397	0.9929078014184397

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP041230

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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Click the colored protein region to show detailed information