CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP019699	Staphylococcus arlettae strain P2 plasmid pSASP2, complete sequence	0 crisprs	NA	0	0	0	0
NZ_AP019698	Staphylococcus arlettae strain P2	2 crisprs	csa3,WYL,DEDDh,cas3,DinG	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP019698_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019698_1

1856107-1856209

Orphan

Consensus_repeat	Method
TAGTGCTCAAGATCAAAACAGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019698_1

>merge|NZ_AP019698|1|1856107-1856209|CRISPRCasFinder
TAGTGCTCAAGATCAAAACAGTTCATCAGAAGCTAGTCAACAAGATGCTGCTGCTTCTGATGACAGTGACGCACAAACTAGCGCTCAAGATCAAAACAGTTCA

>NZ_AP019698|1|1|1856107-1856209|CRISPRCasFinder
TAGTGCTCAAGATCAAAACAGTTCA	TCAGAAGCTAGTCAACAAGATGCTGCTGCTTCTGATGACAGTGACGCACAAAC
TAGCGCTCAAGATCAAAACAGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019698.1\|WP_100218112.1\|1849564_1850698_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_AP019698.1\|WP_142019732.1\|1854145_1854616_+\|DUF2538-family-protein	unknown	unknown	gnl\|CDD\|287742
NZ_AP019698.1\|WP_142019733.1\|1854684_1855107_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
NZ_AP019698.1\|WP_142019737.1\|1863069_1864236_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|236075
NZ_AP019698.1\|WP_002510126.1\|1865806_1866613_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	unknown	unknown	gnl\|CDD\|274729
NZ_AP019698.1\|WP_002510127.1\|1866599_1868282_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl\|CDD\|224087
NZ_AP019698.1\|WP_002510112.1\|1847520_1848126_+\|cytochrome-aa3-quinol-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|131943
NZ_AP019698.1\|WP_142019730.1\|1850771_1852424_-\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NZ_AP019698.1\|WP_142019736.1\|1861947_1862952_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_AP019698.1\|WP_002510125.1\|1864995_1865814_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl\|CDD\|180958
NZ_AP019698.1\|WP_142019731.1\|1852805_1854128_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_AP019698.1\|WP_142019739.1\|1870849_1871404_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP019698.1\|WP_021459248.1\|1848122_1848413_+\|cytochrome-aa3-quinol-oxidase-subunit-IV	unknown	unknown	gnl\|CDD\|225667
NZ_AP019698.1\|WP_142019735.1\|1861335_1861773_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_AP019698.1\|WP_142019738.1\|1864313_1864766_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_AP019698.1\|WP_142019728.1\|1844421_1845543_+\|cytochrome-aa3-quinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|273621
NZ_AP019698.1\|WP_002510114.1\|1848580_1849489_+\|ribonucleoside-hydrolase-RihC	unknown	unknown	gnl\|CDD\|182713
NZ_AP019698.1\|WP_142019729.1\|1845542_1847531_+\|cytochrome-aa3-quinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|131928
NZ_AP019698.1\|WP_002510128.1\|1868274_1869627_-\|isochorismate-synthase	unknown	unknown	gnl\|CDD\|273127
NZ_AP019698.1\|WP_002510129.1\|1869809_1870748_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl\|CDD\|235695

Protein	Function_ID	Function_description	E-value
NZ_AP019698.1\|WP_100218112.1\|1849564_1850698_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	9.40991e-29
NZ_AP019698.1\|WP_142019732.1\|1854145_1854616_+\|DUF2538-family-protein	gnl\|CDD\|287742	pfam10804, DUF2538, Protein of unknown function (DUF2538). This family of proteins has no known function.	6.93484e-99
NZ_AP019698.1\|WP_142019733.1\|1854684_1855107_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	9.38161e-23
NZ_AP019698.1\|WP_142019737.1\|1863069_1864236_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|236075	PRK07683, PRK07683, aminotransferase A; Validated.	5.88465e-160
NZ_AP019698.1\|WP_002510126.1\|1865806_1866613_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	gnl\|CDD\|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	6.94792e-102
NZ_AP019698.1\|WP_002510127.1\|1866599_1868282_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl\|CDD\|224087	COG1165, MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism].	0
NZ_AP019698.1\|WP_002510112.1\|1847520_1848126_+\|cytochrome-aa3-quinol-oxidase-subunit-III	gnl\|CDD\|131943	TIGR02897, AA3-600_quinol_oxidase_subunit_III, cytochrome aa3 quinol oxidase, subunit III. This family (QoxC) encodes subunit III of the aa3-type quinone oxidase, one of several bacterial terminal oxidases. This complex couples oxidation of reduced quinones with the reduction of molecular oxygen to water and the pumping of protons to form a proton gradient utilized for ATP production. aa3-type oxidases contain two heme a cofactors as well as copper atoms in the active site. [Energy metabolism, Electron transport].	6.96641e-103
NZ_AP019698.1\|WP_142019730.1\|1850771_1852424_-\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_AP019698.1\|WP_142019736.1\|1861947_1862952_+\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	1.02738e-58
NZ_AP019698.1\|WP_002510125.1\|1864995_1865814_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl\|CDD\|180958	PRK07396, PRK07396, dihydroxynaphthoic acid synthetase; Validated.	0
NZ_AP019698.1\|WP_142019731.1\|1852805_1854128_+\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	3.6697e-68
NZ_AP019698.1\|WP_142019739.1\|1870849_1871404_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.40652e-09
NZ_AP019698.1\|WP_021459248.1\|1848122_1848413_+\|cytochrome-aa3-quinol-oxidase-subunit-IV	gnl\|CDD\|225667	COG3125, CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Energy production and conversion].	5.46512e-23
NZ_AP019698.1\|WP_142019735.1\|1861335_1861773_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.97787e-13
NZ_AP019698.1\|WP_142019738.1\|1864313_1864766_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.8892e-19
NZ_AP019698.1\|WP_142019728.1\|1844421_1845543_+\|cytochrome-aa3-quinol-oxidase-subunit-II	gnl\|CDD\|273621	TIGR01432, AA3-600_quinol_oxidase_subunit_II, cytochrome aa3 quinol oxidase, subunit II. This enzyme catalyzes the oxidation of quinol with the concomitant reduction of molecular oxygen to water. This acts as the terminal electron acceptor in the respiratory chain. This subunit contains two transmembrane helices and a large external domain responsible for the binding and oxidation of quinol. QuoX is (presently) only found in gram positive bacteria of the Bacillus/Staphylococcus group. Like CyoA, the ubiquinol oxidase found in proteobacteria, the residues responsible for the ligation of Cu(a) and cytochrome c (found in the related cyt. c oxidases) are absent. Unlike CyoA, QoxA is in complex with a subunit I which contains cytochromes a similar to the cyt. c oxidases (as opposed to cytochromes b). [Energy metabolism, Electron transport].	8.31418e-125
NZ_AP019698.1\|WP_002510114.1\|1848580_1849489_+\|ribonucleoside-hydrolase-RihC	gnl\|CDD\|182713	PRK10768, PRK10768, ribonucleoside hydrolase RihC; Provisional.	0
NZ_AP019698.1\|WP_142019729.1\|1845542_1847531_+\|cytochrome-aa3-quinol-oxidase-subunit-I	gnl\|CDD\|131928	TIGR02882, cytochrome_aa3_quinol_oxidase_subunit_I, cytochrome aa3 quinol oxidase, subunit I. This family (QoxB) encodes subunit I of the aa3-type quinone oxidase, one of several bacterial terminal oxidases. This complex couples oxidation of reduced quinones with the reduction of molecular oxygen to water and the pumping of protons to form a proton gradient utilized for ATP production. aa3-type oxidases contain two heme a cofactors as well as copper atoms in the active site. [Energy metabolism, Electron transport].	0
NZ_AP019698.1\|WP_002510128.1\|1868274_1869627_-\|isochorismate-synthase	gnl\|CDD\|273127	TIGR00543, Salicylate_biosynthesis_isochorismate_synthase, isochorismate synthases. This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	2.23205e-117
NZ_AP019698.1\|WP_002510129.1\|1869809_1870748_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	2.72978e-120

>NZ_AP019698.1|WP_142019733.1|1854684_1855107_+|GNAT-family-N-acetyltransferase
MFKIITTEAEKQDAFDIRKEVFVKEQGVPVENELDDYDAIATHIIGYNDNQQPFATARFRQYEQGVKIERVAIHPAFRKSGYGKKLMQFVEKSAAQQGYTKLILNAQLQAKLFYSSLGYNSVGDIFYEEEIKHVKMVKSI
>NZ_AP019698.1|WP_142019732.1|1854145_1854616_+|DUF2538-family-protein
MSRKTYDKLAHINGMFNMLEQQIIHSKDMALFRNEFFYVNHAHRENYEALRIYYKESDVNPVVDGACYIVALPEIFDKVDVFESELPFTWVYDQNGITETMKQISVPIQYLIAAALEVTDVNLFKPSGFTMGMNNWNIAQMRIFWQYSAIVRKEAQ
>NZ_AP019698.1|WP_142019731.1|1852805_1854128_+|LCP-family-protein
MNKLFKYLLILLSLGLVVIPVIYTIMLFKASQGAIDDSFNGSDSNRKSNLRDTKINPSKDPVSILFLGIDENEQRKKNGQSASKSRTDAMIFSTLNPDTQQLRMLSIPRDTISYIPKVGYYDKITHAHAYGGPIASMDAVEGTLNVPVDYYVRINMEAFVDAVNELDGIYYDVPYNLNEPNTNDTGKIKVKKGYQKLNGDEALAVARTRHNDSDLKRGQRQMELIKLLIAKAQKKNSFSKLDDVIKIVGNNSKHNLSSKEVKSLATTYLKSDLDIKTTQLKGEDDYLNNIYYYNPDIKSIMKTSNLLRKDLNLPKINDADKFLNQRVTDFYGTLIPQTEIDQSLLRKNQKDSFESEDESNDESNTNQQQNDTQNMDPNMQQDDSQNSDQNMQQDNSQNMEPNMQQNGNNQSGQSNETQNNDQMAPSADTNQSNQMPTGQY
>NZ_AP019698.1|WP_142019730.1|1850771_1852424_-|phospho-sugar-mutase
MKQQWIEKLDESLVKPFYETQSEEEVEYGFNSTLSFGTAGIRSTFGIGPGKLNAFTVRKVALGLAQFLTAQHATPSVVIHFDTRYLSKEFSEEMAGILAANGVQVILAASYKSTPELSFAVRHLNTTAGVMITASHNPKNYNGIKVYNDAGGQLLPEESTTLSSYIDAIDKPLELTKPDFSELKANQKIQYLDDTVTESYIEAVTKLIDKIEYNNEKVVLTSLHGTSLPILENILTGLDYTNYVIEKEQSQPDGGFPTVKSANPEEVEAFERGISLAQESNANLVIATDPDADRLGIVEVYEDGSYRYFNGNEIGLMLMKLRFQDLADLNQPLYIVKSIVTSELAERLGQLLDVEINNVLTGFKYISELLEEKDAEEEKLLLAFEESHGYLAESISRDKDAIQIVPLIIKYKNLLAQNGLTFNNVINDIYQNIGQFKDKTVALSYEGAAGVNKINAIMDQFRTDTTLPTEMCGLTVKRVEDYQQGIVTNITEQSVQSLSLPKTNLLRFIFDEGFIALRPSGTEPKIKLYFSLNVDNITAIEDQFIAKYVD
>NZ_AP019698.1|WP_100218112.1|1849564_1850698_-|serine-hydrolase
MLVVLTLGGTYLYKYLFNEATKKTIPTNSHNTTRKTNKVVRMNTTMDTTNKVYTQINDYLESVNFNGTITIMQEGELKLNKGYGMKNFDTLQPNDANTMYLIGSSQKFLTGLMLKQLAIAKQINMEASLTQYIPWFQTIYPLNSNDLMLHQSGLFKYQPSEHVTSIQEATQAIQRRGINPKLYKKPQYNDGNYIVLAHLIEVITHQSYEQAFKQMIMQPNDLKFTAFYNDHNLAHNMAIGYKQVNQKPVKQQPRFLNQYYGAGNLFMAPYDMAQLILNLQHNKIFSAVETLPFIKESMTSRYPKAYRFGYYSFPDKNRINGGFYGQVFTVYFNDRYIIVMGTNYEQPHLTNESMLKHIFKHYLKQENHNYNKTGKTY
>NZ_AP019698.1|WP_002510114.1|1848580_1849489_+|ribonucleoside-hydrolase-RihC
MKHPIIIDTDPGIDDAAAISIALNHPDLDVKMLTTVNGNVGIEKTTANALKLTQFFNSNVPVHRGASHPLLSDIFSASSVHGESGMDGYEFQEVDASTLSSHNAVAAMYDLLINSKEPITLIPIGPLTNIALLLTTYPEVKTQIKEIILMGGSAGRGNVTPLAEFNIYCDPEAAHIVFNSGLPLTMVGLDVARSSTLIHAKLEKLKSLNDTGRMLHQLFSHYRGDDFEYGINIYDAYTILYLLHPELFQIVEARVDIETTGELTRGATVTDLKSAYPNCTVVMGIETDIFEKIFFDALTYCK
>NZ_AP019698.1|WP_021459248.1|1848122_1848413_+|cytochrome-aa3-quinol-oxidase-subunit-IV
MNTIVKHTVGFIASIVLTILAVFVTLYTSMTLNAKITIIFGFAFIQAAVQLLMFMHLTEGKDGNLQGFKVIFAIIITLITVIGTYWVMQGGHSSHL
>NZ_AP019698.1|WP_002510112.1|1847520_1848126_+|cytochrome-aa3-quinol-oxidase-subunit-III
MSHDVNTIDARSHEGNLNKLGFWIFLTAEFSLFGTLFAALLTLQYGGDYAGKMTTELFELPLVLIMTFALLISSYTCGIAIYYMRKEKQKLMMIWMIITVLLGAIFVGFEIYEFAHYAHEGVNPTIGSYWSSFFILLGTHGAHVSLGIVWIICLLIQIGMRGLNEDNAPKLFIVSLYWHFLDVVWIFIFTAVYMIGMVFSG
>NZ_AP019698.1|WP_142019729.1|1845542_1847531_+|cytochrome-aa3-quinol-oxidase-subunit-I
MNFPWDQLLVQGNWMITMAQIGAPFMVIGVIAVITYFKLWKYLYREWFTSIDHKKIGAMYLICAVLMFIRGGIDALLMRTQLAIPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWNVIVPLQIGARDVAFPILNNVSFWLFFSGMLLFNLSFIVGGSPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGIGTLMTGINFFVTILRCKTPTMKFMEMPMFTVTTFITALIVILAFPVLTVALALFTTDRIFDTAFFTVADGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMGNGALINSFFSITTMLIGIPTGVKLFNWLFTLYQGRVTFESPMLFALAFIPNFLLGGVTGVMLAMAAADYQYHNTYFLVAHFHYTLVAGVVFACLGALIFWYPKMVGYKLNETLNKWCFWFFMIGFNVCFLPQFVLGLDGMPRRLYTYMPEDGWWMLNLISTIGAVLMAIGFAFLVVSIVYSHFTSPREATGDNWNGLGRTLEWATASAMPPKYNFAITPDWNDYDTFVNMKEHGRHYLDNHNYSEIHMPNNTPVGFWMGIFFTIGGFFLVFETILPAILCLIGIFGTMIYRSFQIDHGYHIPVSEVEETEARLREARKKEREAVSHES
>NZ_AP019698.1|WP_142019728.1|1844421_1845543_+|cytochrome-aa3-quinol-oxidase-subunit-II
MSKFKSLLLLFGSLILLSGCSNVEVLNPKGPMASDSKFLIIYSIIFMLVIMAVVLIMFAYFLFKYRLRNNDESGKMHHNSLIEFIWFVIPVIIVIALAIPTVKSLYQYEAKPEKKDDPIVIYATSAGYKWFFSYPEEKIETVNHLTIPKDRPVVFKLQSMDMMTSFWIPQLGGQKYAMTGMTMDWTMTASETGTFRGRNSNFNGEGFARQVFDVHSVSQSDFKDWVKDAQSKKVLDQDTFDKQLLPTTENKELTFSGTHMAFVDPAADPEYIFYAYDRYNYVQKDPNFNTEEERKKDILDEPDQPKRKPQISNANYERHGMKAMILGNDEPYNNEFKEEESHNMDEMEKLNEGSKDNKASELEKNDQEHGGGH
>NZ_AP019698.1|WP_142019735.1|1861335_1861773_-|MarR-family-transcriptional-regulator
MYRQLEKLITHTSNELNLVSRHLSQRTELSPDHIDLLSILFDYSKLSQYDLTMKLNKEQSIVSRWIKKLCKLGYIMSIQNKTDLRCKDLIITEKSKLLIQQINDSRVALIEARCQSLSQEDILLFQMLLLKLSSLDQYKQNGPRL
>NZ_AP019698.1|WP_142019736.1|1861947_1862952_+|acyltransferase-family-protein
MTQIKERDFFFDNARALLIFLVVFGHLLQPYTESDTFLTSLYLTIYSFHMPCFLFISGYFAKKVGQPGYLEKVSKKLLVPYFIFFAFFSLYYYFTGKEDNVTLDPFDPVFALWFLLTLFFFHIILVLVKNYKPYFVLPIAIIIALFAGFSDDIGNYLSFSRTIIFFPIFYLGYLFKKEHTQVLRNKKFIPLSILVLIVFYIGYTLHPINSDWLLGSSPYTSLEDEEGLYSPLKRLFLYFTILITMFSFLNLVPEKKRIFTYIGTRTLQVYLLHGLFIGIIRGFKIYPFKDPTSFLTYIYLIVVTCIIVYLLSSYKVAKWTNPVINLEKPSNFKG
>NZ_AP019698.1|WP_142019737.1|1863069_1864236_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MKLSLNDRAQYLRAPSIRQFSNRMKDIEDCVNLTIGQPDFNMPQVVKDAYINAINEDMTSYSHNKGLIETRRAVSQYFYHKYNFQYSEEEIIITNGASEALDTSLRSIINIGDEILIPGPIYAGYIPLIETLGGKPVYIDTTHSNYKITPEAIEQHITAKTKAILLNYPTNPTGVTLTFNEVEALVTTLQQHELFIISDEIYAENTFNGTHTSFAQFDSIRDQLLLIGGLSKSHSATGIRIGFLIGPEYLIEKLTFMHAYNCICANVPAQVACIAALNEGLEAPQYMNESYIERKNYLVQKLESLGFELDAQPEGAFYIFPSIRKFTDNDFEFCVQLLEEAHLAIVPGSSFTDYGKGHVRISYAYDLEVLKEGMRRLEHFIAEHYSAV
>NZ_AP019698.1|WP_142019738.1|1864313_1864766_-|MarR-family-transcriptional-regulator
MNNEYGEDARKELCFLFYVSTKEFVNRFNKYLKQYNISFPNYIVLLYIENNIPIYIKTLCEKLYLDSGTISPIIKRLEKKNLIQRTRILEDERRVKVQLTAEGIELKRHFNKISEEVFNQFDMEEEDTRQYHKILKKFTQINVVENSNES
>NZ_AP019698.1|WP_002510125.1|1864995_1865814_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MTRQWETIKEYKEIKYEFYNGIAKVTINRPEVRNAFTPNTVQEMIDAFTRARDDQRISVIILTGEGDKAFCSGGDQKKRGHGGYVGDDQIPRLNVLDLQRLIRIIPKPVIAMVRGYAIGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLAEVEDETVKWCEEIMQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
>NZ_AP019698.1|WP_002510126.1|1865806_1866613_-|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase
MLHYNFHGAQITTDNLIILLHGFISDHSSFDDHIDTLNQHANVLTIDLPGHGDDISANDVTWDFDFIAQQLDEVIRLYASYNIYLHGYSMGGRVALYYALYGNMALTGLILESTSPGIATDSEREERQNVDNARAKVLEIAGLEIFVNDWEKLPLFYTQYELEKPIRKRIRNMRMNQDPYKLAKALRDYGSGYMPSLWSEITHIDIPVAILAGALDQKFVAIGNKMTNLIPRSKFYEVPHVGHTIHVEDASEFDKIVVGFLNKEEQND
>NZ_AP019698.1|WP_002510127.1|1866599_1868282_-|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MTKHVEALTKQVYTLASELYAYGIREVVISPGSRSTPLAIAIEAHPKLTTWIHPDERSAAFFALGLMKGSEKPVAVLCTSGTAAANYTPAVAESQISRLPLVLLTSDRPHELRGIGAPQAINQIQMFENYVQYQFDFPLVDSGENSEKMMDTIAFQMQKASQHLYGPHRGPIHFNLPFREPLTPDLTKVSWLTSDNKALPHYQKTTTLNEIATIIKKKRGLILVGDMQHQEVDQILTYATIHDLPILADPLSQLRKIKHPNVISTYDLMFRAGLELEVDFIIRVGKPVISKVINRWLTQTSAYQILIQNNDRPDAFPIAPHISYEMSANDFFRQLSETVTVERKQWLEKWQLLEVRAQNEVRDYIQSATDEGAYVGHLLDKLTDKDALFVSNSMPIRDVDNLYINCEAEVYANRGANGIDGVVSTAIGMAVHKKVTLLIGDLAFYHDMNGLLMAKLNNINLNIVLLNNDGGGIFSYLPQKNAAEPYFERLFGTPTGLNFEHTALLYDFAFHKFETMADFKYESLSQFGSHIYEIITERDSNQLQHQTLYQKLGDIINATL
>NZ_AP019698.1|WP_002510128.1|1868274_1869627_-|isochorismate-synthase
MTVDVKEDKIVSAVYDSSRTWVSVEAKIDYELDPTMLFQITEDSADDRFFFKKNDNTMSFFGYRAINRFKNDFENKQSIFREWEKYKNDIELIHPNSDKHHLKICGGFQFSSHKSGDEWRQFGINHFILPEVLVTMTEGSTYITYTTKRATFELAKFNAVIQHLTQNTTVIHDDLGKVKRIEDIYKEEWRDLVRDTIAQLNENNKIVLARKRMIQFEKQIKIPFILNQAMQSERNSYLFVLESEDSIFFSQTPEQLMEVKNDVIYTKAVAGTIKRTHDEAEDLRNIEQFLQDTKNLNEHQFVVDSILNDIKPYVNEVNYNESPKILTNDHLYHLLTEITGTLTNESYIGLIDHLHPTPALGGFPKDEAVSYIEKNEFGTRGLYGAPVGFIDMYDDCEFIVAIRSMLIKNQQATLFAGCGIVHDSDPDSEVEETAVKFTPMMRALGVDGND
>NZ_AP019698.1|WP_002510129.1|1869809_1870748_+|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MASQYQQYSTVRKYWQLMRPHTLTAAIVPVLVGTATAKIFLLGSEDHIKISLLLAMLLACLLIQAATNMFNEYYDFKKGLDDHTSVGIGGAIVRNGMSPKLVMNLAIAFYIIAALLGIYLAVQSSFWILPIGLVCMAIGYLYTGGPMPISWTPFGELFSGVFMGGIIILLAFFIQTGNLQTLVVWISVPIIITIGLINMANNIRDRVKDKESGRLTLPIVLGKANSIRFLALMYIVAYAFVVYITFFIPGGSIFFLLALLSFPLPVKAVRRFKKNDTPATMMTAMAATGKTNTFFGVLYALGIYISALLGGI
>NZ_AP019698.1|WP_142019739.1|1870849_1871404_-|GNAT-family-N-acetyltransferase
MIRKAEAKDKVAIAQLCYIIWDELEVDMVKFVERERLLSILERSIVEVPYRGNLNNIWVYEIDGNVAGCLIAYPGEKELEYEKAWLDMDLDHDVAALGTPMPMKEAKDDEYYIETIATFPNYRGRGVATQLIQYVIDLAPHEKWSLNCDYHNERAFYVYNKFGFVTDSDIDLYGHKHRHMIYQQ

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Click the colored protein region to show detailed information

Crispr_ID: NZ_AP019698_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019698_2

2041829-2041937

Orphan

Consensus_repeat	Method
ATATCAGTGTTTATAGGTGTGACCGAAATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019698_2

>merge|NZ_AP019698|2|2041829-2041937|CRISPRCasFinder
ATATCAGTGTTTATAGGTGTGACCGAAATAATTTGGTTCAGTCACAGTAAATATGGAGAATTTTGTTTTAAGCTTGTCATATCAGTGTTTATAGGTGTGACCGAAATAA

>NZ_AP019698|2|2|2041829-2041937|CRISPRCasFinder
ATATCAGTGTTTATAGGTGTGACCGAAATAA	TTTGGTTCAGTCACAGTAAATATGGAGAATTTTGTTTTAAGCTTGTC
ATATCAGTGTTTATAGGTGTGACCGAAATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019698.1\|WP_002455585.1\|2038108_2038582_-\|phage-terminase-small-subunit-P27-family	unknown	unknown	gnl\|CDD\|377461
NZ_AP019698.1\|WP_142019790.1\|2043502_2044387_-\|primase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214926
NZ_AP019698.1\|WP_002455582.1\|2036891_2037227_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_142019795.1\|2045959_2046544_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|376540
NZ_AP019698.1\|WP_037554465.1\|2045644_2045866_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_AP019698.1\|WP_142019791.1\|2044485_2044785_-\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_AP019698.1\|WP_002455584.1\|2037546_2038083_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_002455587.1\|2040236_2040854_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_002455579.1\|2035804_2036215_-\|YolD-like-family-protein	unknown	unknown	gnl\|CDD\|370161
NZ_AP019698.1\|WP_142019794.1\|2045426_2045645_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224393
NZ_AP019698.1\|WP_002455583.1\|2037223_2037550_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_142019792.1\|2044797_2045229_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_002455580.1\|2036224_2036416_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_142019788.1\|2039747_2040221_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_037554559.1\|2041157_2041451_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019698.1\|WP_002510524.1\|2048229_2048694_-\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455
NZ_AP019698.1\|WP_142019793.1\|2045230_2045410_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369018
NZ_AP019698.1\|WP_142019796.1\|2046553_2047660_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_AP019698.1\|WP_142019789.1\|2041969_2043490_-\|nucleoside-triphosphatase	unknown	unknown	gnl\|CDD\|273716
NZ_AP019698.1\|WP_002455578.1\|2035287_2035776_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379324

Protein	Function_ID	Function_description	E-value
NZ_AP019698.1\|WP_002455585.1\|2038108_2038582_-\|phage-terminase-small-subunit-P27-family	gnl\|CDD\|377461	pfam05119, Terminase_4, Phage terminase, small subunit.	2.52287e-18
NZ_AP019698.1\|WP_142019793.1\|2045230_2045410_-\|hypothetical-protein	gnl\|CDD\|369018	pfam06645, SPC12, Microsomal signal peptidase 12 kDa subunit (SPC12). This family consists of several microsomal signal peptidase 12 kDa subunit proteins. Translocation of polypeptide chains across the endoplasmic reticulum (ER) membrane is triggered by signal sequences. Subsequently, signal recognition particle interacts with its membrane receptor and the ribosome-bound nascent chain is targeted to the ER where it is transferred into a protein-conducting channel. At some point, a second signal sequence recognition event takes place in the membrane and translocation of the nascent chain through the membrane occurs. The signal sequence of most secretory and membrane proteins is cleaved off at this stage. Cleavage occurs by the signal peptidase complex (SPC) as soon as the lumenal domain of the translocating polypeptide is large enough to expose its cleavage site to the enzyme. The signal peptidase complex is possibly also involved in proteolytic events in the ER membrane other than the processing of the signal sequence, for example the further digestion of the cleaved signal peptide or the degradation of membrane proteins. Mammalian signal peptidase is as a complex of five different polypeptide chains. This family represents the 12 kDa subunit (SPC12).	0.00743754
NZ_AP019698.1\|WP_142019795.1\|2045959_2046544_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	1.75953e-05
NZ_AP019698.1\|WP_037554465.1\|2045644_2045866_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.019e-09
NZ_AP019698.1\|WP_142019791.1\|2044485_2044785_-\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.50794e-37
NZ_AP019698.1\|WP_002455579.1\|2035804_2036215_-\|YolD-like-family-protein	gnl\|CDD\|370161	pfam08863, YolD, YolD-like protein. Members of this family are functionally uncharacterized. However it has been predicted that these proteins are functionally equivalent to the UmuD subunit of polymerase V from gram-negative bacteria. This family has been shown to belong to the WYL-like superfamily.	1.38644e-21
NZ_AP019698.1\|WP_142019794.1\|2045426_2045645_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	9.20213e-06
NZ_AP019698.1\|WP_142019790.1\|2043502_2044387_-\|primase-C-terminal-domain-containing-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	3.29459e-14
NZ_AP019698.1\|WP_002510524.1\|2048229_2048694_-\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	3.8984e-85
NZ_AP019698.1\|WP_142019796.1\|2046553_2047660_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.40114e-38
NZ_AP019698.1\|WP_142019789.1\|2041969_2043490_-\|nucleoside-triphosphatase	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	2.89699e-111
NZ_AP019698.1\|WP_002455578.1\|2035287_2035776_+\|ATP-binding-protein	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	6.54538e-24

>NZ_AP019698.1|WP_037554559.1|2041157_2041451_-|hypothetical-protein
MADNNLGFNAIDFNDMTMEQLETVLMWCKQLEPIKSFNENYSSYNLKHMFEREPYGFYISNGNMKEAMALAGFKPKNADDLNWFYPISERSIKQLQK
>NZ_AP019698.1|WP_002455587.1|2040236_2040854_-|hypothetical-protein
MTKVNEKSIEVFNKVIEPKVENKKHVALEKSKVTDKLKEFDYKMSHYRNENDFAMIASLKKEQGKLENEIVALHEQSEDDNHKLLDKDIKDFNNAYDKEVKELRDINSKLIQDFNNKLQEVYDVYEKIAANKVEAIRRASRRNYMNTAINNPDQWRLSLQRNTSLVDDPFRTNTDPTTLANSFKEKLFNINGRADSEYNNGNHKW
>NZ_AP019698.1|WP_142019788.1|2039747_2040221_-|hypothetical-protein
MSYTVLSPIKQDYALGFDEKKNTIILKPLYSNSQVGIATVDGVTSSDINYKKGSLTRRVFKNFKDTDGINIVINNNEHSFVANSKDSGVLTVIKEEFIGFGIQVDRVQDKGEGLKELIDIAKNNKSVSVQCYASKLGMDNTTIGNVDKIELVSVNTK
>NZ_AP019698.1|WP_002455585.1|2038108_2038582_-|phage-terminase-small-subunit-P27-family
MAQRKLLSQQKSRLTTEVQETKQATEEALQQLTKLSPEPPEWLDDTATKEWHRIFPLLQEMPVASLDLMLVSTYCQAYSDYINATKRMNNSDVVIVTERGTKLNENHRIKRDSLSQLNSIAPKLGLTVESRLKILDPSKEKTNDKSVYEMFGIDDND
>NZ_AP019698.1|WP_002455584.1|2037546_2038083_-|hypothetical-protein
MILKHCKSVLWYYEEKKITEYELLTHYNPQFINSKIRAIQEQIDAMYHLNVSHTVCDDVMGVISISYPLEKLVLWIIDQKEELNRFKNSSTKKLNLLKKIVHNYTPKEQQEVMRYFKSNGSNKPFKTIDKLQEDLYKVHHHKRLERNKQQEKESEVIYQNFVVEVKQSLNNEHEELVV
>NZ_AP019698.1|WP_002455583.1|2037223_2037550_-|hypothetical-protein
MIGSLNDVDYPILERYMRNYHSMVDTYKNKPSDMNELQYMNLESIVKGVTKVYNDSDVKVQQIIKLTWWDDKKYTDEVIADVIGVGELTLRHAKEVILKRVAKAVDYV
>NZ_AP019698.1|WP_002455582.1|2036891_2037227_-|hypothetical-protein
MSYDKATVKEFILNYHKTINNNDAYNEDINIDDFFNVNDQAEVHDIDNKNVEESIFYNELEAVIESVATEKEHNLFLLLCSGVSFEKAGSIFGVKEARAKQMLNRLLEKLK
>NZ_AP019698.1|WP_002455580.1|2036224_2036416_-|hypothetical-protein
MIPNLDWNKNFQEFQEILNSGINPEWLYNAKANMILNPAYTGEGKQFFFTKDIIKASKTIPFF
>NZ_AP019698.1|WP_002455579.1|2035804_2036215_-|YolD-like-family-protein
MKPINPDVPDEYKCTSDYREIPREYLNSRIPEGRGIVKWQAFKTMPEQYEQLEQYIQDQNKIDKPILDDDQLNELNNTLIFKMYNDPSIELRYFENGYIKNKVGYIHKVDVHTKTLHMYEDTGMSVLNLKDIVEIK
>NZ_AP019698.1|WP_002455578.1|2035287_2035776_+|ATP-binding-protein
MNNLGTLYFFSGKMGAGKSTRSKEIAQTENAVLLSEDEWLEKLYPNQINDFDDYLSYSKLIKPLLKEHIQRILKVGSNVVLDFPGNTKTQRKWLLSVASEINANHQLIFLNISDDKCLKQINIRRSEEPEREQFDTKETFEYVSSFFEPPEFSEGLNIIEIK
>NZ_AP019698.1|WP_142019789.1|2041969_2043490_-|nucleoside-triphosphatase
MVDIYNFAEEETDKLIEEYQHHLQTVQKEKDNIKIFLKQLRKEELDHMRQQWEQAKEKGEASGAPPKTISPNRCAVLLNEHLTFILFDIEEGTKLAFYRQDEGIYTQNYTYIKRVISWLEPSHNQRRAEDVIFHLTNMVNVVPRTNEPHLIPVNNGVFNKETKKLEPFTPDYVFTTKITTNYIEGAVQPTISGWSFDNWLDEVACGDREVFTLLWQVINDSLNGNYTRKKAIFLVGDGNNGKGTFQTLLSNLIGFDNIASLKVNEFDHEFKPSVLEGKTLVIGDDVPVGVNIEDSSNFNSVVTGDSILVNVKKKQPYRAVFRCTVIQSTNGMPRFKNKTGGTNRRLLIVPFNADFNGTKENPDIKEKYLNNKEVLEYVLYKAINLDFGKFIVPKVSADMLEEYKQDNDPAYDFKVTEFDTWKIDKVPKSVVYYRYKVFCENSGYHALSERKFYKTFNQYLSKNWEEERARFYSVADMQKKVGYFEPTLVPNGELKRSYINNKLKVV
>NZ_AP019698.1|WP_142019790.1|2043502_2044387_-|primase-C-terminal-domain-containing-protein
MGFEQIKLQHDIRLNIIEYKNLSSYSFVQTNDVMWSEWLNRLQTPMNHNEKYQRGLVVYGDVKDVEQDGKLIQKYRNDENIINRNTLALDYDDIEDFKGLYSAICKQLEGFCWAFHTTYNHTTEKPRIRLMVPVNEPVSADDYRKYTQALAQKIGYKIDEGSFQPSRAMALPVKPDKNIPYIFKYNDAPAITIGDLNELSRNINSQKNKPITINYSSQYKKRDSSYWRDIAFGVGEGERNQTLASLIGYLLRRYVDVNLVYGLAIAWAQQCTPPIDDKEVNNTFRSILKKDLNR
>NZ_AP019698.1|WP_142019791.1|2044485_2044785_-|DUF1474-family-protein
MNWETKSLIEDVDIIKRKINDAVTTFGCFDDEYFTYDSGHMLTKDEILKHGASYHEHRCYITQHIDLLSLYLKELDKVLEDIEKASSENNSLPTKSDNA
>NZ_AP019698.1|WP_142019792.1|2044797_2045229_-|hypothetical-protein
MTNYENIPQIEIVREFKSKYGREIALMLISDRVNNKKMNKDDRELREYELIKAYMEHQDINDKYIGDLDILDMVTDFERMIKMSVNATNILTVLGTSGNEMQNEISYFSREDDLNNLYLAKLEIEKLIKAIEKNRTEYINFYK
>NZ_AP019698.1|WP_142019793.1|2045230_2045410_-|hypothetical-protein
MKLFGILITASSLTSFAVGYVTEDIFNSLALYSPLAVVSWAITEWFYDRKIKKQLLEEN
>NZ_AP019698.1|WP_142019794.1|2045426_2045645_-|helix-turn-helix-domain-containing-protein
MKKLAYPHLYIQRKEHGHNQAFVAHKLGISKERYSLKELNKANFTLPEAKILSELYGMPIDQLFSNSITVGQ
>NZ_AP019698.1|WP_037554465.1|2045644_2045866_-|helix-turn-helix-transcriptional-regulator
MVNRIKEIRLEKSITITELSNITGVSRTTIYKLEEQKSNPSLETISRISSGLKERPEKIFNFSVIQELQKEEA
>NZ_AP019698.1|WP_142019795.1|2045959_2046544_+|helix-turn-helix-domain-containing-protein
MNEFGNKLKELRGKQSIREASRNIGISHTYLDSLEKGYDPRTGKERKPTIEVINKISEYYNYDFFKLVNLAGLFVSISEAPEKVKKDEIQKMKKRFEDFAITKENRVKSEYLDLFSEKLNYNEVMFFEKIYTFFETERYSEELSIKNGADIDPLSFIGIIFDFLVENKNSHKIEAYDDIMNEFSEFLKEYLNIK
>NZ_AP019698.1|WP_142019796.1|2046553_2047660_+|tyrosine-type-recombinase/integrase
MQHDLKLSHNIYKDAKRGTYYFRIKYYEKTGERKEIKRTGYKQRKEAVKACNAYMNEIEGIGKINQLPFDELVQEYVEWYSARRKASSLKSLKTHTNNHLVPFFQSMDVFNMTTQDIMKFQNKKMKEAHSGEYLKKMHVFLVSILNHAMKYHDLKQNVASLVGNFEIETQKRLNYWTLEQFNQFHDMLPNLQQKVFFKLLFMSGARKGEIRALTWDDVNFDDDYIHINKTDYHGIVTAPKTKASIRDIYLPAHMMDDLQEYLNWYKDNNIYKSNYVLFGTFFKAFSESAIDRWFTGTLKKLDETLPDGETFPRIVIHELRHSHASMLVNHGASPMIIAQRLGHSSTEEVTSRYGHLYPSTQKEIIKYL
>NZ_AP019698.1|WP_002510524.1|2048229_2048694_-|SsrA-binding-protein-SmpB
MPKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVKRGEIYLQNMHIAPYEEGNRFNHDPRRSRKLLLHKREIIKLGERTREIGYSIVPLKLYLKHGNCKVLLGIARGKKKYDKRQALKEKAVKRDVDRAMKARY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1098681 : 1136756

Staphylococcus_phage(88.89%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142019568.1\|1098681_1099830_+	DegT/DnrJ/EryC1/StrS family aminotransferase	A0A2D2W2B8	Stenotrophomonas_phage	8.1e-12	25.2
WP_103388009.1\|1099929_1100556_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_142019569.1\|1102395_1103778_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	9.0e-159	59.1
WP_103387794.1\|1103795_1104791_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.5e-94	52.1
WP_021459078.1\|1104787_1105021_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	3.0e-30	80.6
WP_021459079.1\|1105080_1105554_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.6e-43	55.4
WP_002509985.1\|1105540_1106335_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.4e-92	67.8
WP_002510562.1\|1108047_1109643_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.3e-257	80.6
WP_002510563.1\|1110016_1111213_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	3.8e-190	85.1
WP_002510564.1\|1111305_1112214_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.4e-107	78.5
WP_002510565.1\|1112343_1113180_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	8.8e-109	66.4
WP_002510566.1\|1113233_1113587_-	CrcB family protein	NA	NA	NA	NA
WP_021459821.1\|1113579_1113951_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	2.4e-34	63.1
WP_002510568.1\|1114148_1114454_-	hypothetical protein	NA	NA	NA	NA
WP_002510569.1\|1114734_1115448_+	transaldolase	R9TM64	Synechococcus_phage	8.5e-20	33.3
WP_002510570.1\|1115821_1116271_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.4e-20	45.3
WP_002510571.1\|1116278_1116713_-	competence protein ComK	NA	NA	NA	NA
WP_037580146.1\|1116728_1117199_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.6e-22	44.1
WP_002510573.1\|1117411_1117636_+	hypothetical protein	NA	NA	NA	NA
WP_002510574.1\|1117775_1118630_+	glucosaminidase domain-containing protein	Q4ZE13	Staphylococcus_virus	6.6e-43	38.9
WP_002510575.1\|1119192_1120116_-	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_021459818.1\|1120289_1121765_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	9.4e-13	65.5
WP_002510577.1\|1122181_1123225_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.7e-130	66.2
WP_002510578.1\|1123231_1123864_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.4e-68	61.9
WP_002510579.1\|1123878_1125060_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.0e-163	71.2
WP_002510580.1\|1125072_1125537_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.6e-59	75.3
WP_142019570.1\|1125746_1126781_-	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	7.5e-126	69.2
WP_002510582.1\|1127041_1127866_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_142019571.1\|1128041_1128992_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_002510584.1\|1129154_1129556_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_002510585.1\|1129596_1130157_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	3.3e-67	65.4
WP_002510586.1\|1130153_1131107_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.6e-66	84.8
WP_142019572.1\|1131215_1132394_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	3.8e-158	71.9
WP_142019573.1\|1132696_1135114_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	84.0
WP_002510589.1\|1135135_1135447_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-34	66.0
WP_002510590.1\|1135496_1136756_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	5.0e-39	78.1

DBSCAN-SWA_2

1273198 : 1289419

uncultured_Mediterranean_phage(44.44%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002510442.1\|1273198_1274200_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	4.9e-05	29.1
WP_142019611.1\|1274202_1275228_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002510444.1\|1275247_1276387_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	6.0e-84	43.6
WP_002510445.1\|1276403_1276664_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	5.7e-06	44.1
WP_142019612.1\|1276898_1279175_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.0e-29	36.1
WP_142019613.1\|1279365_1281642_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.7e-66	29.0
WP_002510448.1\|1281658_1282177_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.5e-29	46.3
WP_021459896.1\|1282517_1284707_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	4.1e-12	38.0
WP_103387844.1\|1284720_1285173_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002510451.1\|1285169_1286045_+	N-acetylmuramoyl-L-alanine amidase	A0A067ZJB6	Vibrio_phage	7.8e-15	31.7
WP_112369439.1\|1286377_1287646_+\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_002510453.1\|1287652_1289419_+\|tRNA	aspartate--tRNA ligase	A0A2K9L3L6	Tupanvirus	1.5e-04	32.2

DBSCAN-SWA_3

1832222 : 1840691

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002510860.1\|1832222_1832789_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.8e-28	38.2
WP_002510861.1\|1832785_1833820_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	4.8e-64	43.9
WP_142019725.1\|1833812_1835300_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-42	31.3
WP_002510863.1\|1835278_1837468_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.0e-137	38.4
WP_021459050.1\|1837460_1838132_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002510865.1\|1838131_1838392_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002510866.1\|1838393_1839095_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	3.1e-46	42.5
WP_142019726.1\|1839094_1840222_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002510868.1\|1840208_1840691_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.1e-21	44.0

DBSCAN-SWA_4

2026753 : 2051104

Staphylococcus_phage(52.17%)

terminase,head,integrase

attL 2044544:2044560|attR 2050398:2050414

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142019783.1\|2026753_2027347_+	hypothetical protein	A0A1D6Z277	Staphylococcus_phage	1.4e-12	68.4
WP_142019784.1\|2028685_2029084_-	DUF1722 domain-containing protein	NA	NA	NA	NA
WP_142019785.1\|2029111_2029303_-	hypothetical protein	U3PCX8	Staphylococcus_phage	1.4e-25	85.0
WP_142019786.1\|2029446_2030658_-	Fic family protein	Q9AZ49	Lactococcus_phage	1.5e-37	28.0
WP_172604825.1\|2030875_2031019_-	hypothetical protein	NA	NA	NA	NA
WP_142019787.1\|2031104_2031446_-	sigma-70 family RNA polymerase sigma factor	A0A2H4JEH8	uncultured_Caudovirales_phage	1.5e-19	45.6
WP_142020101.1\|2031442_2031721_-	hypothetical protein	A0A2H4JEA5	uncultured_Caudovirales_phage	1.5e-17	46.7
WP_002455574.1\|2032414_2032975_+	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_037554456.1\|2033149_2033467_-\|head	phage head closure protein	A0A2I7SC03	Paenibacillus_phage	1.2e-10	41.1
WP_037554460.1\|2034087_2034609_+	hypothetical protein	A0A0H3U494	Staphylococcus_phage	1.0e-83	83.2
WP_002455577.1\|2034601_2035105_+	hypothetical protein	A0A0H3U2S7	Staphylococcus_phage	1.1e-26	67.7
WP_002455578.1\|2035287_2035776_+	ATP-binding protein	A0A2H4JFX6	uncultured_Caudovirales_phage	3.2e-87	100.0
WP_002455579.1\|2035804_2036215_-	YolD-like family protein	U3PG23	Staphylococcus_phage	3.7e-68	91.2
WP_002455580.1\|2036224_2036416_-	hypothetical protein	U3PCX8	Staphylococcus_phage	2.9e-31	100.0
WP_002455582.1\|2036891_2037227_-	hypothetical protein	NA	NA	NA	NA
WP_002455583.1\|2037223_2037550_-	hypothetical protein	A0A2H4JEA5	uncultured_Caudovirales_phage	1.4e-22	47.6
WP_002455584.1\|2037546_2038083_-	hypothetical protein	A0A2H4JB26	uncultured_Caudovirales_phage	5.4e-43	50.8
WP_002455585.1\|2038108_2038582_-\|terminase	phage terminase small subunit P27 family	A0A2H4JB21	uncultured_Caudovirales_phage	1.7e-53	68.8
WP_142019788.1\|2039747_2040221_-	hypothetical protein	A0A1W6JPF7	Staphylococcus_phage	6.0e-30	39.5
WP_002455587.1\|2040236_2040854_-	hypothetical protein	A0A1W6JPC6	Staphylococcus_phage	6.6e-53	53.7
WP_037554559.1\|2041157_2041451_-	hypothetical protein	NA	NA	NA	NA
WP_142019789.1\|2041969_2043490_-	nucleoside triphosphatase	A0A1P8BMT9	Lactococcus_phage	9.1e-104	44.6
WP_142019790.1\|2043502_2044387_-	primase C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	9.7e-82	51.7
WP_142019791.1\|2044485_2044785_-	DUF1474 family protein	A0A1W6JPG5	Staphylococcus_phage	5.5e-37	79.8
2044544:2044560	attL	NA	NA	NA	NA
WP_142019792.1\|2044797_2045229_-	hypothetical protein	NA	NA	NA	NA
WP_142019793.1\|2045230_2045410_-	hypothetical protein	NA	NA	NA	NA
WP_142019794.1\|2045426_2045645_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_037554465.1\|2045644_2045866_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_142019795.1\|2045959_2046544_+	helix-turn-helix domain-containing protein	A0A1W6JPB6	Staphylococcus_phage	5.0e-10	26.6
WP_142019796.1\|2046553_2047660_+\|integrase	tyrosine-type recombinase/integrase	H0UST3	Bacillus_phage	3.2e-74	42.7
WP_002510524.1\|2048229_2048694_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	7.9e-75	92.9
WP_002510525.1\|2048716_2051104_-	ribonuclease R	Q0GXV6	Lactococcus_phage	6.2e-91	38.4
2050398:2050414	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2108595 : 2126811

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002509864.1\|2108595_2109564_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.0e-136	77.6
WP_142019804.1\|2110028_2110997_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	7.2e-171	91.0
WP_002508884.1\|2111103_2113209_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.4
WP_002508885.1\|2113171_2113570_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	3.1e-51	72.7
WP_142019805.1\|2114247_2115138_+	EamA family transporter	NA	NA	NA	NA
WP_002508887.1\|2115162_2115663_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.4e-53	72.3
WP_002508888.1\|2115944_2117459_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	9.2e-72	36.8
WP_021459144.1\|2117842_2119345_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.2e-66	35.6
WP_002508890.1\|2119483_2120422_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	4.0e-09	25.8
WP_002508891.1\|2120471_2121008_-	5'-3'-deoxyribonucleotidase	A0A0A0PKY7	Bacillus_phage	2.7e-26	36.6
WP_002508892.1\|2121088_2122144_-	histidinol-phosphate transaminase	A0A142C026	Faustovirus	3.4e-17	24.0
WP_142019806.1\|2122332_2123847_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_142019807.1\|2123843_2124800_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	2.1e-29	35.2
WP_002508895.1\|2125032_2126811_-	DNA helicase RecQ	M1PGQ0	Moumouvirus	1.7e-77	37.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP019698

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection