CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017196	Leuconostoc gelidum subsp. gelidum strain TMW 2.1618 chromosome, complete genome	1 crisprs	csa3,cas3,DEDDh,cas9,cas1,cas2,csn2	0	5	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017196_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017196_1

540553-541380

TypeII

Consensus_repeat	Method
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	PILER-CR
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CRISPRCasFinder
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CRT

12 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP017196_1

>merge|NZ_CP017196|1|540553-541380|PILER-CR,CRISPRCasFinder,CRT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCCATACGGATATAAAGAGTTAACGTCTAATGGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCATAATCCAGAGTTGTTAAAGCGTTTGAATGGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCTATTCAACAAGTTGCTAATTTGGGAACAAGGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCTATCAGTATGCAATGACTTCTCTTCCCACTGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCGCCGCCGCGCACAATTAACAAGAAGGCTGGGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCCCTGACTACTAATACCTTGAACAGCTGCATGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCTTAGGATACTGCACAATTACAGCACACCCAGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCCACTAAAAGGTTAAGGGGAGAAGTTCCATGGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCACAGTAACAGGAATTTGGAACGTGTTTGTTGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCTTGCGTGAAATCAGTCGTCACACGCCGGTCGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCATCGATATAGCTAACTCCACTTAATCCAGTGCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACCAGTGAACTAAAGAAGGCTTATTCTAATTCTGCTTCAGATGTGTGTCAGATCAATGAAGTTCAAAAC

>NZ_CP017196|1|1|540553-541380|PILER-CR
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CATACGGATATAAAGAGTTAACGTCTAATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ATAATCCAGAGTTGTTAAAGCGTTTGAATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TATTCAACAAGTTGCTAATTTGGGAACAAG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TATCAGTATGCAATGACTTCTCTTCCCACT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	GCCGCCGCGCACAATTAACAAGAAGGCTGG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CCTGACTACTAATACCTTGAACAGCTGCAT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TTAGGATACTGCACAATTACAGCACACCCA
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CACTAAAAGGTTAAGGGGAGAAGTTCCATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ACAGTAACAGGAATTTGGAACGTGTTTGTT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TTGCGTGAAATCAGTCGTCACACGCCGGTC
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ATCGATATAGCTAACTCCACTTAATCCAGT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	AGTGAACTAAAGAAGGCTTATTCTAATTCT
GCTTCAGATGTGTGTCAGATCAATGAAGTTCAAAAC

>NZ_CP017196|1|1|540553-541380|CRISPRCasFinder
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CATACGGATATAAAGAGTTAACGTCTAATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ATAATCCAGAGTTGTTAAAGCGTTTGAATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TATTCAACAAGTTGCTAATTTGGGAACAAG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TATCAGTATGCAATGACTTCTCTTCCCACT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	GCCGCCGCGCACAATTAACAAGAAGGCTGG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CCTGACTACTAATACCTTGAACAGCTGCAT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TTAGGATACTGCACAATTACAGCACACCCA
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CACTAAAAGGTTAAGGGGAGAAGTTCCATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ACAGTAACAGGAATTTGGAACGTGTTTGTT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TTGCGTGAAATCAGTCGTCACACGCCGGTC
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ATCGATATAGCTAACTCCACTTAATCCAGT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	AGTGAACTAAAGAAGGCTTATTCTAATTCT
GCTTCAGATGTGTGTCAGATCAATGAAGTTCAAAAC

>NZ_CP017196|1|1|540553-541380|CRT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CATACGGATATAAAGAGTTAACGTCTAATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ATAATCCAGAGTTGTTAAAGCGTTTGAATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TATTCAACAAGTTGCTAATTTGGGAACAAG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TATCAGTATGCAATGACTTCTCTTCCCACT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	GCCGCCGCGCACAATTAACAAGAAGGCTGG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CCTGACTACTAATACCTTGAACAGCTGCAT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TTAGGATACTGCACAATTACAGCACACCCA
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	CACTAAAAGGTTAAGGGGAGAAGTTCCATG
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ACAGTAACAGGAATTTGGAACGTGTTTGTT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	TTGCGTGAAATCAGTCGTCACACGCCGGTC
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	ATCGATATAGCTAACTCCACTTAATCCAGT
GCTTCAGATGTGTGTCAGATCAATGAGGTTCAAACC	AGTGAACTAAAGAAGGCTTATTCTAATTCT
GCTTCAGATGTGTGTCAGATCAATGAAGTTCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017196.1\|WP_174249014.1\|552822_553569_+\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP017196.1\|WP_174249002.1\|529389_530154_+\|nicotinamide-mononucleotide-transporter	unknown	unknown	gnl\|CDD\|273672
NZ_CP017196.1\|WP_174249016.1\|555531_556437_+\|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl\|CDD\|234631
NZ_CP017196.1\|WP_174249009.1\|544312_545608_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NZ_CP017196.1\|WP_010017026.1\|533429_534350_+\|type-II-restriction-endonuclease	unknown	unknown	gnl\|CDD\|377384
NZ_CP017196.1\|WP_174249666.1\|532627_533440_+\|DNA-adenine-methylase	unknown	unknown	gnl\|CDD\|273146
NZ_CP017196.1\|WP_174249015.1\|553571_555485_+\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP017196.1\|WP_174249010.1\|545798_547055_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NZ_CP017196.1\|WP_010017266.1\|528880_529318_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP017196.1\|WP_174249006.1\|539555_539861_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP017196.1\|WP_174249003.1\|530201_531344_+\|nicotinamide-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273670
NZ_CP017196.1\|WP_174249012.1\|550394_551363_+\|methionyl-tRNA-formyltransferase	unknown	unknown	gnl\|CDD\|234567
NZ_CP017196.1\|WP_174249007.1\|539857_540532_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP017196.1\|WP_174249008.1\|541563_544092_+\|enterotoxin	unknown	unknown	gnl\|CDD\|283125
NZ_CP017196.1\|WP_174249004.1\|534409_538477_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP017196.1\|WP_174249013.1\|551355_552717_+\|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB	unknown	unknown	gnl\|CDD\|237857
NZ_CP017196.1\|WP_174249005.1\|538671_539544_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP017196.1\|WP_014947663.1\|531494_532271_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|131468
NZ_CP017196.1\|WP_174249011.1\|547801_550219_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NZ_CP017196.1\|WP_010017036.1\|547054_547639_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770

Protein	Function_ID	Function_description	E-value
NZ_CP017196.1\|WP_174249014.1\|552822_553569_+\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.47551e-63
NZ_CP017196.1\|WP_174249002.1\|529389_530154_+\|nicotinamide-mononucleotide-transporter	gnl\|CDD\|273672	TIGR01528, Protein_pnuC., nicotinamide mononucleotide transporter PnuC. The PnuC protein of E. coli is membrane protein responsible for nicotinamide mononucleotide transport, subject to regulation by interaction with the NadR (also called NadI) protein (see TIGR01526). This model defines a region corresponding to most of the length of PnuC, found primarily in pathogens. The extreme N- and C-terminal regions are poorly conserved and not included in the alignment and model. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	6.5783e-34
NZ_CP017196.1\|WP_174249016.1\|555531_556437_+\|ribosome-small-subunit-dependent-GTPase-A	gnl\|CDD\|234631	PRK00098, PRK00098, GTPase RsgA; Reviewed.	1.60532e-119
NZ_CP017196.1\|WP_174249009.1\|544312_545608_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	1.44661e-144
NZ_CP017196.1\|WP_010017026.1\|533429_534350_+\|type-II-restriction-endonuclease	gnl\|CDD\|377384	pfam04556, DpnII, DpnII restriction endonuclease. Members of this family are type II restriction enzymes (EC:3.1.21.4). They recognize the double-stranded unmethylated sequence GATC and cleave before G-1. http://rebase.neb.com/rebase/enz/DpnII.html.	2.50137e-68
NZ_CP017196.1\|WP_174249666.1\|532627_533440_+\|DNA-adenine-methylase	gnl\|CDD\|273146	TIGR00571, DNA_adenine_methylase, DNA adenine methylase (dam). All proteins in this family for which functions are known are DNA-adenine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). The DNA adenine methylase (dam) of E. coli and related species is instrumental in distinguishing the newly synthesized strand during DNA replication for methylation-directed mismatch repair. This family includes several phage methylases and a number of different restriction enzyme chromosomal site-specific modification systems. [DNA metabolism, DNA replication, recombination, and repair].	1.88026e-83
NZ_CP017196.1\|WP_174249015.1\|553571_555485_+\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.08912e-115
NZ_CP017196.1\|WP_174249010.1\|545798_547055_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_CP017196.1\|WP_010017266.1\|528880_529318_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	5.7596e-85
NZ_CP017196.1\|WP_174249006.1\|539555_539861_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.12732e-22
NZ_CP017196.1\|WP_174249003.1\|530201_531344_+\|nicotinamide-nucleotide-adenylyltransferase	gnl\|CDD\|273670	TIGR01526, nadR_NMN_Atrans, nicotinamide-nucleotide adenylyltransferase, NadR type. The NadR protein of E. coli and closely related bacteria is both enzyme and regulatory protein. The first 60 or so amino acids, N-terminal to the region covered by this model, is a DNA-binding helix-turn-helix domain (pfam01381) responsible for repressing the nadAB genes of NAD de novo biosynthesis. The NadR homologs in Mycobacterium tuberculosis, Haemophilus influenzae, and others appear to lack the repressor domain. NadR has recently been shown to act as an enzyme of the salvage pathway of NAD biosynthesis, nicotinamide-nucleotide adenylyltransferase; members of this family are presumed to share this activity. E. coli NadR has also been found to regulate the import of its substrate, nicotinamide ribonucleotide, but it is not known if the other members of this model share that activity.	1.6778e-106
NZ_CP017196.1\|WP_174249012.1\|550394_551363_+\|methionyl-tRNA-formyltransferase	gnl\|CDD\|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	7.98908e-129
NZ_CP017196.1\|WP_174249007.1\|539857_540532_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.9478e-68
NZ_CP017196.1\|WP_174249008.1\|541563_544092_+\|enterotoxin	gnl\|CDD\|283125	pfam05382, Amidase_5, Bacteriophage peptidoglycan hydrolase. At least one of the members of this family, the Pal protein from the pneumococcal bacteriophage Dp-1 has been shown to be a N-acetylmuramoyl-L-alanine amidase. According to the known modular structure of this and other peptidoglycan hydrolases from the pneumococcal system, the active site should reside at the N-terminal domain whereas the C-terminal domain binds to the choline residues of the cell wall teichoic acids. This family appears to be related to pfam00877.	1.13723e-24
NZ_CP017196.1\|WP_174249004.1\|534409_538477_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	8.42971e-106
NZ_CP017196.1\|WP_174249013.1\|551355_552717_+\|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB	gnl\|CDD\|237857	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB.	0
NZ_CP017196.1\|WP_174249005.1\|538671_539544_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.03806e-89
NZ_CP017196.1\|WP_014947663.1\|531494_532271_+\|glucose-1-dehydrogenase	gnl\|CDD\|131468	TIGR02415, Diacetyl_reductase, acetoin reductases. One member of this family, as characterized in Klebsiella terrigena, is described as able to interconvert acetoin + NADH with meso-2,3-butanediol + NAD(+). It is also called capable of irreversible reduction of diacetyl with NADH to acetoin. Blomqvist, et al. decline to specify either EC 1.1.1.4 which is (R,R)-butanediol dehydrogenase, or EC 1.1.1.5, which is acetoin dehydrogenase without a specified stereochemistry, for this enzyme. This enzyme is a homotetramer in the family of short chain dehydrogenases (pfam00106). Another member of this family, from Corynebacterium glutamicum, is called L-2,3-butanediol dehydrogenase (). [Energy metabolism, Fermentation].	1.10664e-89
NZ_CP017196.1\|WP_174249011.1\|547801_550219_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NZ_CP017196.1\|WP_010017036.1\|547054_547639_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	1.07135e-110

>NZ_CP017196.1|WP_174249007.1|539857_540532_+|type-II-A-CRISPR-associated-protein-Csn2
MNYSIVCFPNNPIKIIPGLTMISIANHELYWQLSTGLKETSEDVTLGQNGHIADVNKAVMFIGDIGAQLDVNKLYQKNIVNTMKNYADDQALEVFYKINSELNHVLENIILENNLPFYFQTEFNIVELINEKKFKIETLTNSSGFGKIEDVVSVAGEFSEQRLIVFTNLYLLLSVDQIDYLNNLAKTMNLCLISLNLTQNPVMTKQGLPPEVFIDEDFVQFGAD
>NZ_CP017196.1|WP_174249006.1|539555_539861_+|CRISPR-associated-endonuclease-Cas2
MRVMIFFDLPTLTDVDRRNYRHFRKSLINEGFLMIQESVYVRVTTNRQAAALLEKRIQTITPVDGLVQSLIVTEKQYTMMKFLSGTPSDDIRNSDEKMVVI
>NZ_CP017196.1|WP_174249005.1|538671_539544_+|type-II-CRISPR-associated-endonuclease-Cas1
MAWRTVVVTKHSKLNYKMNHLVVQTAEKTYQIPMEDIQIILITTTQAVVTAYVIAETIKRNIKIIFSDINGQPIGEINQYHTNGKHNRNISEQIIWTSQRKNLLWSEIIKRKIENQMQVLFVYQSADREKFQALIAGIEVGDETNREAVAARMYFNRLFGNEFVRHEAGIVNAMLDYGYQILMAAVAREIVLQGYLSELGIHHNGAQNDYNLASDLMEPFRPLVDAVAKKHEHEMALNLDIKLALVDIINQVIEINGQQMLVANAITILVRDAINYLNSGLKLPEWRFEI
>NZ_CP017196.1|WP_174249004.1|534409_538477_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTYSIGLDIGTGSVGWAVIGDDYRLKRARGKNLIGVRLFDSATTAAERRGYRTTRRRLSRRHWRLRLLNDIFASDLAEQDENFLPRLKYSWVNPDDEQNPQLNSDVANGALFGSSETDKAFHKNYPTIYHLRHELMTDTAKHDLREVYLAIHHIVKYRGNFLNTADKINTENSFDVDLFVAALDEYNEFLETPITSINDAQLFSDKLTDINARNKSVRVENAMSETYDSKSKIFKAILTALVGNTANFQTIFDLSDLEKDEVKNFKFKLDLEDVETKLDVVRAKLSDEQNAFLEAILIAYDGITLKMILGDYKSISQSMIESYKSHQRDWKYIKNNVRLNEQKIEPDKNSVKFFKLDPKKLIYPSNLAYLQVISSNEDEHRKGLDYFKTAIQDVDILQRIENDTFLPRQRTKRNGVLPYQLHLAELEQIIEKQSKYYPFLANTYTQDNKTENKLIGLLKFRVPYYVGPLVEAEKVTGDGKNHWLIKKELQENTPITPFNFDDVVDKDKSGEQFIKRITGTDSYLIGEPTLPENSLLYQKYNVLQELNNVRNERHQRLPIKVKQDIFEHVFKIDKNVNAKKVMAYLKLNGYGDFQIAGLSDTRTGNFNSNLSSYNYFVELLGREKTEKIEEDRLEEIIEIQTVFEDKSIVAKRLSNLDFLTPQEKSQLSAKHYTGWGRLSQKLLTTQFIKTALSEAGDIIPQSHSIIDLLYYTDKNLIEILNDKKFKVQDWLTEQNSSIASGNSLYDQIDALAGPKDIKRGITQVFSIMDDIKKAMGSNPETVYLEFARETQASRLTNSRLNHVQEIYNSPQLKTEFAHLVKKLETETKESIQDDRLYLYYLQEGQDMYTKDEIPFEQISSNYDIDHIIPQSFTKDDSFDNRVLVNRATNARKSNSPTFTNDIIDKRKVWWQSLVKHGLMSKEKFERLTDKRSNFSENQTSHFIARQLVETRQIIKNVADLIKNNYDGTQAVAVRASLTGEMRHYLRWPKNRDMNDYHHAHDALMVATVGKYIDRRGFFDKGNVSDGAKNAYNLYTKDWLSAARAGTKNDSQRVNPFGFIVGSMNSEAVRQQVNKETGEIVWKNENVDYLRHVLDYKKIVVTRRLRGSSGRLYAETLFSPNPKAKLIAQKANRSVALYGGFTKAESAYMALVEFNKKGDRSYKLIKVPMTIVNRVNNKQITVTTYIESLKLRDFSRVVLEQLPLGTLIRESDGSEFYAATSEMKHNAKELWASKEILKSSKRLDKATTEDLIDIFDFLISDKTINHFKFYERDLLHLKNVRDKFVEASDGIKLKMLADIIYELHNDAGWRDPFKHIQEKPAWTMLQVKGGIKLSEKAAIVYQSPTGLFETINIVGE
>NZ_CP017196.1|WP_010017026.1|533429_534350_+|type-II-restriction-endonuclease
MVSKMNVYEYRNLPINQRLEYFVSTLSNIEKFADYWVNFDNVYKNVPQKLAPDLFTLDYLIGKDQMEIESFFHERPYLLMLVPLLLGIRKDKLDQYGNLSVQDIQEKYQLNFNDINTENMSAYFDFLTHSGLMNLLSQGLKKSVFDYSVGVQAGMDSNGRKNRSGKIGEKFLEERLSAIASKNDLKWMGQSTPSKIKKEFDVDIEQIFENRRFDGALYNPRKLKIILFEINLFNASGSKSKSASTEFQTLRDRLAKTNHEFIYITDGEGWLKDKSHLKEALEYIGNVFNVSMVEDGYIESVLDLKR
>NZ_CP017196.1|WP_174249666.1|532627_533440_+|DNA-adenine-methylase
MKWVGGKRQLLPELAKYVPEHFGTYFEPFLGGGAFLLALSPEHAVINDFNPELVVSWMIVRDRPEELLKQLKQHQLNHSKEYYLHLRAADRDGRLEKMTLVQRAARFIYMNKTGFNGLWRVNKKGQNNVPFGSYKNPNISDKDTIKPAARYLNDAQITITNADFEKAILDAQTGDFVYFDPPYIPISETSSFTAYSSDFGYDQQVRLRDVFVALHQKGVHVMLSNSDVPLIEKLYGHIDGIVIEHVSVTHMVAAKASSRKKVGEVIVHGK
>NZ_CP017196.1|WP_014947663.1|531494_532271_+|glucose-1-dehydrogenase
MSEKVAIVTGGGQGIGEGIALRLAKDGYAVIVNGRTEHKLTKVVNKIEAAGGQASLFVGDVQSRQVNFDLVQFAMEKYGRLDTFIANAGIDWVDTIEETPEEQVDNILNINLKSQIWALQAAPTALRKNGKQGGTIILASSIAGMEGFEMLGIYSATKFAARGLMQAAAKELAVDNIRVNAYNPGIVLTPMWDEIDARFAERKNVPVGSTRQAFIDGILLGRGEEPEDIAKYVSFLVSDQADYITGQSLAVDGGIKFQ
>NZ_CP017196.1|WP_174249003.1|530201_531344_+|nicotinamide-nucleotide-adenylyltransferase
MRTFAGNLFKDDLEGEKIGVFFGTLAPMHVGHQAEIYKAAALNDGVVVIASGYTGDRGDQMGLSVEKRFRYLREAFSDETAIKVDYINEDNIPQMPAGWDEWTKILVHTVKRNVVNQNAKITFYTGEAEYKLNLEKRLPQTGQFTVSLMDRTVLKISATDIRKNPIGNWDYINRVFRRHFTKKVTVMGSASTGKSTLVRRLARTSNSPFSEEYAREYQERSNVSDDELVVKDYIRLIQGQYDANSKEINSPANNGLTIFDTDAMVTKVYADLWLSKEDSRQLQPLFDNTISEELIDLILIIPPVTPYTHDGFRNMNNTDDKSRWAFHNELMRVIKHYGFMDKVVLLDAKGEGEDPYGYYARYLQALDAIQERTGFNIKHL
>NZ_CP017196.1|WP_174249002.1|529389_530154_+|nicotinamide-mononucleotide-transporter
MENVRKNDFWRYFNPVNIVKELLLGWTIPEAILLIVLVFLQGAVWGLGVMHTHNFDWFGLATGLMNIITVVLVAKGRITNYFWGLVYSVMYMPLAFQSQLFGEVALSAFWVVMQFVGIIAWLGFMKRDTSTEKSDQAVVTTKYMSRKQWLFVIPVFLVLLAIVGLILEQAGSRQPYMDGMTTTISMGAQILQTEKFAESWYAWLLFDIVELILWGRAWTGHADPSAFAMLGMNLALTVNAIYGIVQWRKLTKKE
>NZ_CP017196.1|WP_010017266.1|528880_529318_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEKYTDEALKKRLTPEAYQVTQHAATERAFTGEYDQWWEAGIFVDIVSGEPLFSSTDKYDAGCGWPSFTQSIDDQHIKRHVDQSFGMTRTEVTSRDANSHLGHLFTDGPTEKGGLRYCINSASLKFVPKNELVAAGYGKYLSLFE
>NZ_CP017196.1|WP_174249008.1|541563_544092_+|enterotoxin
MVNKKLRVKELLVSTIIIGGVLGTMSTVNAAENTAHVSTQVPSTITSGSSGTSQAPSTKTSSSTINESRQNDNYNVTPSTRSIQVHQAKFKTGSVIALTNSAKTSNGTQLQNYGDQSGVVTNVISPKHANLDYTYDVKLDNGMVVSSVLEQGVVSFDKISVFSINNHVAIKKDATHDPDGKNISAYRGFSGTITKVTRYHQLSSNFYYQITLDNGVVVAKILEQDLQRYTNKPVHKDGWSSENGVTKYYVNGAAIVGEKKIDGHWYNFASNGVQSKGLTTLAHKTVFYDMKSGQMAYGYVWTNGTLMFFDTSDGHALTGVRHYNGGVEVYGTDFKQIRNNYATVGSSRYYLTGNGDAFKGSRETNGQLEFYGTNYVQVRNNYTWLNGSLMFFDSNGHAVTGVRYYGSNMEYYDANHKQIRNSYMRTGNTYYYLKANGDAFKGLRQYSATGLEYYGSDFKQIRHNYATTNGSTYYFNGDGDAIKGTRIVNDKLEYYDNNYKQVRNNYAWLDGSLMFFDGNGHAMTGIRYYGSNMEYYDANHKQIRNSYVKTGNTYYYMKANGDAFKGLRQYSTTGLEYYGSDFKQVRNQSVTIGDKIYHFNKDGDADSIQSKNPTTARYAKNTSAYITNNADQSVNGDHNLKKYAGQQVKIISAKAEKQSNWLYTVELNNGTIIKDVLEQDLQESKVNFKVNTNKLIDWFESRKGKLTYSMYGSRNGTDGTADCSGSVVQAIRDAGGTPFTWLYNTEAIHTYLKDNSYQIIDNNDPYGWMSRRGDIVIWGQQGHSDGADGHIGIITNNLDNPLFISTCYITQGQKGTAVQEVRYNQFVSENGYPYYYVYRSAQ
>NZ_CP017196.1|WP_174249009.1|544312_545608_+|trigger-factor
MSNWTATEDQKNQGTLEFKISRAQVEAGLEKAFQQNKNDVSIPGFRKGKVTKALFFSKFGEEALYQQTMDIVLPTAYEAAVDESGITPVGRPNIEPVSMNKGEDWTMKAEITTAPEVKLGEYLNLEVEAADTEVTDADVEAEIKHLQDGQAELVLQEASVKAENGDTVIIDFDGSVDGDHFDGGQADDFSLELGSGQFIPGFEEQLVGHSAGEDVNVTVTFPKDYQAADLANKEALFEVKIHELKRKELPEIDDEFAKDVDEEVETLAELKEKTAKKLTEDKAESAQAAFEDAVIKKAVDNASIDGDKVPEAMIDEDVHRQIDQYLAQLQQQGISREMFFQISGQTEDDLHKQFEEGAETRVKTNLVLEAIVKAEAIEPSEDQINEEVTNLATQYKMEAAQVRANLSDSLLKHDIAMREVIKRVTDSAKAK
>NZ_CP017196.1|WP_174249010.1|545798_547055_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MAQTPDLEEEIYCSFCGKSASEVRQIVAGPSGIYICNECVDLAKNIMSEELTVDQTVAKPITLALPTPHEIVSELNDYVIGQDDAKKTLAVAVYNHYKRINENYTPTTDVELQKSNIALIGPTGSGKTYLAQSLARILDVPFAIADATTLTEAGYVGEDVENIVLKLLQSANFDIDAAQHGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKMLEGTIASVPPQGGRKHPQQELIQVDTTNILFIVGGAFAGIDTIIKERLGERVIGFGSDANDNAIALESENILEHVQPEDMTKFGLIPEFIGRLPIVTVLDELKIDDLTRILTEPKNALIKQYTVLLGLDDVILEFQPDALEAMAELAIKRHTGARGLRSIIELTMKDVMYDIPSRDDVSKVIITKASVVDGEQPELQLKKVN
>NZ_CP017196.1|WP_010017036.1|547054_547639_+|YihA-family-ribosome-biogenesis-GTP-binding-protein
MDVHNVDMVMSAVSAAQYPTDGKPEIALVGRSNVGKSSLTNTLIQRKNFARTSSQPGKTQTLNFYNVEDKLYFVDVPGYGYAKVSKKQREEFGHMIEEYITSRKQLRGVVSLVDARHEPSDDDVSMYEWLHYYNIPILIVATKSDKISKSKFNKYASNIKQTLGFNEDESDFQFFSSETKYGKDQVWKWIEAHI
>NZ_CP017196.1|WP_174249011.1|547801_550219_+|primosomal-protein-N'
MTKLQYAQIIVDVPTMQTNQPYTYVIPESMIESVRPGMRVDVPFGHRHVMGFVVGLRATTDLETNKLRHINNLLDLTPVLNTELLNLSDYLAQETFAFRISVLQTMLPNALRASYERILKIIDEVDDDVRDRIFKGLDEILYQARELNVRDIATLTKLQREHKIEASVNVTNRSKIKTQLAYQFNGDVEFLENERQDLRPTAKKQFELLMFIMGHLEEVWVKKTLQEMISVSDATLNQGVEKKWLSKKKVEQLRDPFSMNDIIPTTALTLNEEQQNALNHIVASSDAQQYQPFLLEGITGSGKTEVYLQAAQHVFDQEKTVLFLVPEIALTPQMVRRVKSRFGAQTAVLHSGLSDGERYDEWRRIERGDAKIVVGARSAVFAPLDNIGLIIVDEEHETTYKQTDNPRYNARDIALWRGEYYQIPVVLGSATPSLESRARAQRGVYELLRLTERAGGAKLPAVDVIDMKATLADGPETNFSEQLKNKLQDRLKRGEQSVLMLNRRGFSSFVMCRDCGFVPRDPNCNLAMTLHMDSHTLKCHYCGHEEPIPVICANCGSNRIRYYGTGTEKVETELATLLPEARVIRMDQDTTRKKGSMDKMLQKFGNHEADILLGTQMIAKGLDFPDVTLVGVLNADTSLGLPDFHASERTFQLLTQVSGRAGRAKKAGEVLVQTFNPQHYAIVYAKQHDYEGFYQQEMAVRHAGNYAPYYYTVQIQASHVTENETAKQMIQIARWLRSRVDDKVIILGPSPKPIAKLRNRYYFQIILKFKHQHEMDVLLTELQNRAQKSKNGLQLMIDREPVSFM
>NZ_CP017196.1|WP_174249012.1|550394_551363_+|methionyl-tRNA-formyltransferase
MTYSVVLMGTPQFAVPILEALIADDKYDVKAVVTQPDKPQGRKHILKPSPVKITALAHNLPVLQPEKIGDSDDMQQIIALNPDFIVTAAFGQFLPNKLLEAAKIAAVNTHASLLPKYRGGAPVHYAIMNGDTETGVSIMYMVKKMDAGDIIDVVKVPITNQDNVGTMFNKLSLAGRDLLLASLPKIATGDISPVKQNDNDVSFSPNIPHHMQNLNFTSETAQQIDWHLRGLYPTHPAHVQVSGQRVKLMKVTPLDEKTDLDAGHVVEKTKKQLKISAADQTVVSIDRLQPAGKSEMDIVAYLNGAGNQLQTGDLWAEEPINE
>NZ_CP017196.1|WP_174249013.1|551355_552717_+|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB
MSDKRVYSDNPRVLAVQTLAKIKNGAYSNLQLNQVIKQHQLSEADKRLLTTLVYGVIQHRMTFEYWLAPFVGDKKIDAWVRELLYSAIFQMKFLDKIPEHAIFNESIEVAKILGHVGTGKYVTAILHNIGRQGLRSTSDIKEPIQRLSIERSLPIWLIEELISQNGEETTRAMLETINDAPQQSIRVNTTLASDKEVEQALATEKFTTVKSRVAAHAYIVSGGHVAGSKAFHDGLLTLQDESAMLPVESMRLTENVKTILDAAAAPGGKTTQIAQSVGENVTITALDIHEHKIKLIRSNAERLHVTEKIHTRVLDARKVPTEIDQKFDRILVDVPCSGFGLLRRKPEIRYDKTLADVENLAHLQFEILDSVSQNVTDNGMIVYSTCTILRQENDDVITKFLLKHSDFELVPTQTSKNLKPNRSENVLHVYPNDYQTDGFFVATLQRKIPTDSV
>NZ_CP017196.1|WP_174249014.1|552822_553569_+|serine/threonine-protein-phosphatase
MQIAFHTDSGVKRNENQDYVGAFTNQKGNVMVMVADGVTSTEGGEVASAMAVEHFGHAWEKTTIETIKPSIAWIKETVAFENDVIIEAGQRFDDLKTMATTLVLAILFDEQVVIGNLGDSKAFLLHHNSLKQISFDHNLKNELVRTGTVSQKQAEHIPNANSVTRFLGVDRHADIEIGQHKFSDEDMLFLTSDGITKVLNKTTIKQIMRTATTLDLRAHELIRSANNNGASDNVTALLVSRNNEEDTK
>NZ_CP017196.1|WP_174249015.1|553571_555485_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MLPDTVIDNRYKIIKSLGGGGMANVYLAHDEFLDRDVTFKMMRLDMKNDVELAKRFQRDAISATELVHDNIVQVYDTGEYEGTQYLVMEYVAGNDLKSFIAEHFPIPYQQVVDIMTQVLSAVQAAHDADIIHRDLKPQNILIDKNCQVKITDFGIAIAKSVQDMTQTNTVIGSVHYLSPEQTRGGLASAKSDIYALGVMLYEMLTKQVPYEGDTPVAVAMKHTTEEMPSVRDFDPRIPQALENVILKATAKRPQDRYLSAAAMSEDLNTTLSPRRSDEIRFAPMSDTIDETRIIPMAQIQDQLKTGVSSDKIFPDEVPEEPSIKDVIISHGKKGYSVKDIAHIVDRTPNYVRSVLRGNGIKFRKSSKWPWVLVGLILMAVAVTVFLNYQSNKTTVPNVINLTQDQATMKIKKAGLVVGTVSSTPSKTITNGHVVRTTRSSGAEAKKGDTINLIISSGRAKVRFGDYVGSDYDVTATQLRAQGYSVTRKDSPSDSVSEGRIILQSVDANGKVDPTATNVEFTVSTGAQRINVPDFTGKSTQEQVQSWASEHDIVVNFNTQYDGNTKKDHVISQSIRGGSSITKDMVLLVTISQGPQVSSSDSSDDSSSSDGSSSSSSSSSSSSSSSSSSSASSSKNKN
>NZ_CP017196.1|WP_174249016.1|555531_556437_+|ribosome-small-subunit-dependent-GTPase-A
MKTGRIIRSLSGYYDIQISNGEVQRTRARGEFRKSGQKPLVGDFVDFESENDEGLIWKIYPRENVLVRPLIANIDVAVIVTALKEPDFAPNLLDRQLVALAAARVTPLIYFTKADLLTESEYIHATEVSNRYLKIGYTTILPAMNNINGNFFELRSELRGKVAVFMGQTGAGKSTLLNHLSPELGLETGIVSKALSRGKHTTRQVTLIQVNDALIADTPGFSSYEVFDFPVEQLAGYFPEFVAVRQNCRFRGCLHLNEPGCAVKESVTVGAIAQSRYNSYKAFYDLIKSQKPRYNTDNRNI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017196_1	1.7\|540985\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540985-541014	30	AJ131519	Lactobacillus bacteriophage phi adh complete genome	21515-21544	5	0.833
NZ_CP017196_1	1.7\|540985\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540985-541014	30	NC_000896	Lactobacillus prophage phiadh, complete genome	21515-21544	5	0.833
NZ_CP017196_1	1.6\|540919\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540919-540948	30	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	391307-391336	6	0.8
NZ_CP017196_1	1.6\|540919\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540919-540948	30	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	384697-384726	6	0.8
NZ_CP017196_1	1.7\|540985\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540985-541014	30	MN856101	Myoviridae sp. isolate 109, complete genome	22751-22780	6	0.8
NZ_CP017196_1	1.7\|540985\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540985-541014	30	NZ_CP022359	Shewanella bicestrii strain JAB-1 plasmid pSHE-CTX-M, complete sequence	113802-113831	6	0.8
NZ_CP017196_1	1.5\|540853\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540853-540882	30	MF140432	Arthrobacter phage Teacup, complete genome	35075-35104	7	0.767
NZ_CP017196_1	1.6\|540919\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540919-540948	30	NZ_CP028799	Acinetobacter junii strain WCHAJ59 plasmid p2_010059, complete sequence	3955-3984	7	0.767
NZ_CP017196_1	1.6\|540919\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540919-540948	30	NC_012858	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132502, complete sequence	14892-14921	7	0.767
NZ_CP017196_1	1.6\|540919\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540919-540948	30	NZ_CP054023	Rhizobium sp. JKLM12A2 plasmid pPR12A202, complete sequence	172841-172870	7	0.767
NZ_CP017196_1	1.6\|540919\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540919-540948	30	NZ_CP054033	Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence	330050-330079	7	0.767
NZ_CP017196_1	1.4\|540787\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540787-540816	30	MG883712	Microviridae sp. isolate Pig170, complete genome	5383-5412	8	0.733
NZ_CP017196_1	1.5\|540853\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540853-540882	30	NZ_CP023280	Nostoc sp. CENA543 plasmid pCENA543a, complete sequence	12455-12484	8	0.733
NZ_CP017196_1	1.3\|540721\|30\|NZ_CP017196\|PILER-CR,CRISPRCasFinder,CRT	540721-540750	30	NZ_CP003562	Flammeovirga sp. MY04 plasmid unnamed, complete sequence	73284-73313	9	0.7

1. spacer 1.7|540985|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to AJ131519 (Lactobacillus bacteriophage phi adh complete genome) position: , mismatch: 5, identity: 0.833

ttaggatactgcacaattacagcacaccca	CRISPR spacer
cctgaatactgcacaattacagcacatcca	Protospacer
.. *.*********************.***

2. spacer 1.7|540985|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NC_000896 (Lactobacillus prophage phiadh, complete genome) position: , mismatch: 5, identity: 0.833

ttaggatactgcacaattacagcacaccca	CRISPR spacer
cctgaatactgcacaattacagcacatcca	Protospacer
.. *.*********************.***

3. spacer 1.6|540919|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 6, identity: 0.8

cctgactactaataccttgaacagctgcat	CRISPR spacer
gctgaatacgaataccttgaacaggagtat	Protospacer
 **** *** **************  *.**

4. spacer 1.6|540919|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 6, identity: 0.8

cctgactactaataccttgaacagctgcat	CRISPR spacer
gctgaatacgaataccttgaacaggagtat	Protospacer
 **** *** **************  *.**

5. spacer 1.7|540985|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to MN856101 (Myoviridae sp. isolate 109, complete genome) position: , mismatch: 6, identity: 0.8

ttaggatactgcacaattacagcacaccca	CRISPR spacer
cccgagtactgcacaattacggcacaccca	Protospacer
.. *..**************.*********

6. spacer 1.7|540985|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022359 (Shewanella bicestrii strain JAB-1 plasmid pSHE-CTX-M, complete sequence) position: , mismatch: 6, identity: 0.8

ttaggatactgcacaattacagca-caccca	CRISPR spacer
ccaggacactgcacaattacagcagcagct-	Protospacer
..****.***************** ** *.

7. spacer 1.5|540853|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to MF140432 (Arthrobacter phage Teacup, complete genome) position: , mismatch: 7, identity: 0.767

gccgccgcgcacaattaacaagaaggctgg	CRISPR spacer
tcttcgccgcgcaatcaacaagaaggctgg	Protospacer
 *. *  ***.****.**************

8. spacer 1.6|540919|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028799 (Acinetobacter junii strain WCHAJ59 plasmid p2_010059, complete sequence) position: , mismatch: 7, identity: 0.767

cctgactactaataccttgaacagctgcat	CRISPR spacer
caatcctactaataccttgaacaacagcaa	Protospacer
*    ******************.* ***

9. spacer 1.6|540919|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NC_012858 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132502, complete sequence) position: , mismatch: 7, identity: 0.767

-----cctgactactaataccttgaacagctgcat	CRISPR spacer
agggcgctg-----taataccttgaactgctgcat	Protospacer
      ***     ************* *******

10. spacer 1.6|540919|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054023 (Rhizobium sp. JKLM12A2 plasmid pPR12A202, complete sequence) position: , mismatch: 7, identity: 0.767

-----cctgactactaataccttgaacagctgcat	CRISPR spacer
agggcgctg-----taataccttgaactgctgcat	Protospacer
      ***     ************* *******

11. spacer 1.6|540919|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054033 (Rhizobium sp. JKLM13E plasmid pPR13E02, complete sequence) position: , mismatch: 7, identity: 0.767

-----cctgactactaataccttgaacagctgcat	CRISPR spacer
agggcgctg-----taataccttgaactgctgcat	Protospacer
      ***     ************* *******

12. spacer 1.4|540787|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to MG883712 (Microviridae sp. isolate Pig170, complete genome) position: , mismatch: 8, identity: 0.733

tatcagtatgcaatgacttctcttcccact	CRISPR spacer
tataagaatgcaatgacttctctatgtgca	Protospacer
*** ** **************** . ..*

13. spacer 1.5|540853|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023280 (Nostoc sp. CENA543 plasmid pCENA543a, complete sequence) position: , mismatch: 8, identity: 0.733

gccgccgcgcacaattaacaagaaggctgg	CRISPR spacer
ttcgccgcgctcaattaacaagatagaagt	Protospacer
 .******** ************ .*  *

14. spacer 1.3|540721|30|NZ_CP017196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP003562 (Flammeovirga sp. MY04 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

tattcaacaagttgctaatttgggaacaag	CRISPR spacer
aattgaacaagttgctaatttgtatgtatt	Protospacer
 *** ***************** . ..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

401249 : 411575

Streptococcus_phage(50.0%)

protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_174248942.1\|401249_403415_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.6e-136	43.8
WP_010015313.1\|403484_405491_+	excinuclease ABC subunit UvrB	A0A2K9VDA5	Lactobacillus_phage	4.7e-07	27.7
WP_174248943.1\|405613_408484_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	8.7e-281	52.0
WP_010015310.1\|408546_408669_-	putative metal homeostasis protein	NA	NA	NA	NA
WP_014947678.1\|408936_409911_+	YvcK family protein	A1IMD5	Streptococcus_phage	4.5e-80	47.8
WP_174248944.1\|409910_410855_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-41	35.2
WP_010015307.1\|410972_411575_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.1e-48	53.3

DBSCAN-SWA_2

787855 : 828086

Streptococcus_phage(22.22%)

protease,transposase,integrase

attL 787394:787408|attR 793668:793682

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
787394:787408	attL	NA	NA	NA	NA
WP_174249124.1\|787855_788098_+\|transposase	transposase	Q6J1X3	Lactobacillus_phage	1.2e-05	37.0
WP_174249125.1\|788143_788737_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_174249126.1\|788765_788948_+\|transposase	transposase	NA	NA	NA	NA
WP_174249127.1\|789458_792269_+	hypothetical protein	NA	NA	NA	NA
WP_174249128.1\|793015_794341_+	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	9.1e-84	39.3
793668:793682	attR	NA	NA	NA	NA
WP_174249129.1\|794333_794711_+	hypothetical protein	E3W8I0	Leuconostoc_phage	6.3e-14	36.8
WP_174249130.1\|794697_794949_+	hypothetical protein	NA	NA	NA	NA
WP_174248743.1\|795218_795512_-	hypothetical protein	NA	NA	NA	NA
WP_174249131.1\|795529_795823_-	hypothetical protein	NA	NA	NA	NA
WP_174249132.1\|795838_796189_-	hypothetical protein	NA	NA	NA	NA
WP_174249133.1\|796163_796406_-	hypothetical protein	NA	NA	NA	NA
WP_174249134.1\|797005_797218_-	hypothetical protein	NA	NA	NA	NA
WP_174249135.1\|797210_797654_-	hypothetical protein	NA	NA	NA	NA
WP_174249136.1\|797650_797878_-	hypothetical protein	NA	NA	NA	NA
WP_174249137.1\|798292_798553_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5SCV8	Streptococcus_phage	1.2e-19	51.2
WP_090090295.1\|798552_798768_-	CopG family transcriptional regulator	NA	NA	NA	NA
WP_174249138.1\|798832_799039_-	hypothetical protein	NA	NA	NA	NA
WP_174249139.1\|799020_799398_-	hypothetical protein	NA	NA	NA	NA
WP_174249140.1\|799511_799943_-	JAB domain-containing protein	NA	NA	NA	NA
WP_174249141.1\|800401_800668_+	hypothetical protein	NA	NA	NA	NA
WP_174249142.1\|800654_802910_+	toprim domain-containing protein	NA	NA	NA	NA
WP_174249143.1\|802925_803408_+	hypothetical protein	NA	NA	NA	NA
WP_174249144.1\|803404_805306_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	2.8e-62	30.7
WP_174249145.1\|805292_808313_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_174249146.1\|808309_810412_+	hypothetical protein	NA	NA	NA	NA
WP_174249147.1\|810474_810978_+	hypothetical protein	NA	NA	NA	NA
WP_174249148.1\|811059_811560_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_174249675.1\|811502_812408_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.5e-45	39.8
WP_174249149.1\|812477_812759_-	hypothetical protein	NA	NA	NA	NA
WP_174249150.1\|812758_813538_-	ParA family protein	A0A1V0DZZ0	Clostridioides_phage	5.7e-17	25.0
WP_060391577.1\|813913_814243_+	hypothetical protein	NA	NA	NA	NA
WP_174249151.1\|814242_814896_+	hypothetical protein	NA	NA	NA	NA
WP_174249152.1\|816855_817050_+	hypothetical protein	NA	NA	NA	NA
WP_174249153.1\|817053_818301_+	M23 family metallopeptidase	A0A1W6JQH9	Corynebacterium_phage	1.5e-06	36.1
WP_174249154.1\|818314_818746_+	thioredoxin family protein	NA	NA	NA	NA
WP_174249155.1\|818742_819300_+	hypothetical protein	NA	NA	NA	NA
WP_174249156.1\|819302_819899_+	hypothetical protein	NA	NA	NA	NA
WP_174249157.1\|820208_820553_+	hypothetical protein	NA	NA	NA	NA
WP_174249158.1\|820757_821147_+	hypothetical protein	NA	NA	NA	NA
WP_174249159.1\|821162_823277_+	hypothetical protein	NA	NA	NA	NA
WP_174249160.1\|823288_824170_+	class A sortase	NA	NA	NA	NA
WP_174249161.1\|827093_828086_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.8e-36	34.0

DBSCAN-SWA_3

1160781 : 1174001

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010385946.1\|1160781_1161552_-	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.1e-16	30.4
WP_010016924.1\|1161548_1162388_-	phosphate ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	2.9e-11	28.4
WP_014947482.1\|1162467_1163352_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_010385941.1\|1163351_1164275_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_010385939.1\|1164403_1165285_-	phosphate ABC transporter substrate-binding protein PstS family protein	R9S7J3	Prochlorococcus_phage	4.4e-10	27.3
WP_174249274.1\|1165382_1166738_-	GHKL domain-containing protein	W8CYF6	Bacillus_phage	1.9e-28	35.5
WP_060391362.1\|1166807_1167713_-	phosphate ABC transporter substrate-binding protein	H6WG65	Cyanophage	3.5e-10	27.0
WP_174249686.1\|1167894_1168587_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-37	38.2
WP_013231401.1\|1168698_1169844_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	4.9e-118	66.6
WP_089998903.1\|1169978_1170560_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_060391360.1\|1170569_1171448_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_089998907.1\|1171461_1172733_-	insulinase family protein	A0A2K9V7S4	Bandra_megavirus	6.4e-18	33.8
WP_010016937.1\|1172729_1174001_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.6e-43	30.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage