CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP041514	Klebsiella michiganensis strain KNU07 plasmid unnamed, complete sequence	0 crisprs	csa3,RT	0	0	3	0
NZ_CP041515	Klebsiella michiganensis strain KNU07 chromosome, complete genome	2 crisprs	WYL,DEDDh,DinG,cas3,csa3	0	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10292 : 66372

Bacillus_phage(26.67%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009309912.1\|10292_10928_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_009309911.1\|11035_11380_-	hypothetical protein	NA	NA	NA	NA
WP_047057603.1\|12828_13269_-	hypothetical protein	NA	NA	NA	NA
WP_009309909.1\|13287_13881_-	hypothetical protein	NA	NA	NA	NA
WP_001261282.1\|14172_14403_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001044770.1\|14399_14816_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_009309907.1\|14889_16452_+	AAA family ATPase	NA	NA	NA	NA
WP_000361404.1\|16436_17459_+	helicase UvrD	NA	NA	NA	NA
WP_032425603.1\|18002_18911_+	HNH endonuclease	NA	NA	NA	NA
WP_004187110.1\|19096_19447_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	6.0e-19	51.4
WP_004196883.1\|19533_19938_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	1.1e-69	99.3
WP_004196919.1\|19934_20282_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	3.3e-62	99.1
WP_004196907.1\|20330_21869_+\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	7.4e-295	99.2
WP_020803533.1\|22056_22488_-	silver-binding protein SilE	NA	NA	NA	NA
WP_003032875.1\|22738_24214_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_001572351.1\|24206_24887_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	35.6
WP_000475512.1\|25076_26462_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246153.1\|26490_26844_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_004152079.1\|26957_28250_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_004098958.1\|28260_31407_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	4.0e-61	22.5
WP_008322815.1\|31493_31934_+	hypothetical protein	NA	NA	NA	NA
WP_004098955.1\|32060_34508_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	7.6e-84	35.8
WP_000843497.1\|34548_34746_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004182013.1\|34779_35517_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
WP_001023257.1\|35805_36255_-	copper resistance protein	NA	NA	NA	NA
WP_000925242.1\|36488_38306_+	multicopper oxidase PcoA	NA	NA	NA	NA
WP_001242438.1\|38305_39202_+	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_000025662.1\|39241_39622_+	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_004118344.1\|39626_40556_+	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_001188930.1\|40610_41291_+	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
WP_004152084.1\|41287_42688_+	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	4.1e-18	26.3
WP_004152085.1\|42904_43339_+	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
WP_024623170.1\|43570_43750_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_004196769.1\|45490_46000_+	major intrinsic family protein	NA	NA	NA	NA
WP_004196778.1\|46049_46547_-	N-acetyltransferase	NA	NA	NA	NA
WP_004152092.1\|46878_47205_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004182005.1\|47922_48468_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004152095.1\|48543_48906_+	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_004152096.1\|50802_51339_+	N-acetyltransferase	NA	NA	NA	NA
WP_004152097.1\|51371_51797_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.3e-52	72.9
WP_004152098.1\|51809_53099_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4J144	uncultured_Caudovirales_phage	1.9e-171	74.0
WP_048289678.1\|54956_55961_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_004152100.1\|56257_56620_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_004152101.1\|56669_57020_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_004152102.1\|57377_57647_+	hypothetical protein	NA	NA	NA	NA
WP_004152103.1\|57634_58210_+	hypothetical protein	NA	NA	NA	NA
WP_004152104.1\|58240_58735_+	DNA-binding protein	NA	NA	NA	NA
WP_004152105.1\|58778_59147_+	hypothetical protein	NA	NA	NA	NA
WP_004152106.1\|59180_59384_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004152107.1\|59432_59690_+	hypothetical protein	NA	NA	NA	NA
WP_004152108.1\|59765_60020_+	hypothetical protein	NA	NA	NA	NA
WP_003026799.1\|60195_60462_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003026803.1\|60449_60932_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_077253535.1\|61139_62486_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_004143398.1\|62534_62930_+	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_077255298.1\|63127_64474_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_101827254.1\|65355_66372_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7

DBSCAN-SWA_2

70180 : 127076

Escherichia_phage(26.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049014947.1\|70180_73165_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	4.4e-304	53.9
WP_004206571.1\|73324_73903_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	3.9e-23	37.7
WP_049015982.1\|74078_75284_+	chromate efflux transporter	NA	NA	NA	NA
WP_004206574.1\|75294_75600_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_049015986.1\|76181_76607_+	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.8e-50	71.4
WP_000928911.1\|78760_79111_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000043177.1\|79415_79892_-	DNA starvation/stationary phase protection protein	G0X506	Salmonella_phage	6.7e-05	28.7
WP_016241611.1\|80006_80444_-	PaaI family thioesterase	NA	NA	NA	NA
WP_143444184.1\|80604_81066_-	dinitrogenase iron-molybdenum cofactor	NA	NA	NA	NA
WP_001137910.1\|81040_81361_-	DUF134 domain-containing protein	NA	NA	NA	NA
WP_072196656.1\|81425_81632_-	hypothetical protein	NA	NA	NA	NA
WP_004393997.1\|82118_82829_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-31	38.3
WP_022652303.1\|82830_84036_-	ABC transporter permease	NA	NA	NA	NA
WP_016236501.1\|84032_85184_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_049015493.1\|85180_85789_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_016236507.1\|86143_86479_+	hypothetical protein	NA	NA	NA	NA
WP_000156887.1\|86700_87723_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_031591991.1\|88218_88644_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	6.1e-50	70.0
WP_031591992.1\|88656_89946_-	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	3.5e-173	74.0
WP_032694617.1\|89992_91744_-	arsenical pump-driving ATPase	NA	NA	NA	NA
WP_049015829.1\|91760_92123_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_025376942.1\|92170_92524_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	1.1e-23	48.7
WP_016241603.1\|93417_93708_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_024196088.1\|93808_94684_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000019445.1\|94682_95663_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	1.0e-185	99.4
WP_064381628.1\|96058_96679_+	recombinase family protein	A0A1V0E035	Clostridioides_phage	9.4e-07	29.6
WP_040118531.1\|96698_96962_+	hypothetical protein	NA	NA	NA	NA
WP_064381635.1\|97062_97992_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	3.2e-75	55.0
WP_101827254.1\|98317_99334_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7
WP_004098901.1\|99377_101225_-	diol dehydratase reactivase subunit alpha	NA	NA	NA	NA
WP_004098899.1\|101237_101669_-	diol dehydratase small subunit	NA	NA	NA	NA
WP_004098897.1\|101665_102256_-	propanediol/glycerol family dehydratase medium subunit	NA	NA	NA	NA
WP_004098894.1\|102269_103937_-	propanediol/glycerol family dehydratase large subunit	NA	NA	NA	NA
WP_004098893.1\|104330_104759_+	heme-binding protein	NA	NA	NA	NA
WP_004098891.1\|104796_105960_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_101827236.1\|106029_106395_+	hypothetical protein	NA	NA	NA	NA
WP_004098883.1\|106396_106945_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_004098881.1\|106922_108848_-	PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR	NA	NA	NA	NA
WP_004098879.1\|108987_110088_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_004098877.1\|110684_111755_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_004098873.1\|112414_113842_+	dihydroxyacetone kinase subunit DhaM	NA	NA	NA	NA
WP_143444187.1\|114206_114803_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	9.1e-116	100.0
WP_143444190.1\|116572_117445_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_143444207.1\|117437_117509_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_143444192.1\|117724_117994_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_143444210.1\|118132_118696_-	DUF1669 domain-containing protein	A0A1B2LRT6	Wolbachia_phage	1.7e-18	34.3
WP_143444195.1\|118707_119328_-	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_143444198.1\|120076_120868_-	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_143444201.1\|120977_121568_-	fertility inhibition protein FinO	NA	NA	NA	NA
WP_143444204.1\|121692_122418_-	type-F conjugative transfer system pilin acetylase TraX	NA	NA	NA	NA
WP_004118541.1\|124067_127076_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	62.8

DBSCAN-SWA_3

184890 : 193806

Macacine_betaherpesvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032425559.1\|184890_185862_-	StbA family protein	A0A222YXF2	Escherichia_phage	1.4e-73	46.8
WP_032425560.1\|186110_187595_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_099144854.1\|187594_187846_-	hypothetical protein	NA	NA	NA	NA
WP_009309980.1\|188000_188426_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.9e-31	50.4
WP_004206782.1\|188425_189697_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	8.6e-156	64.0
WP_004206783.1\|189775_190027_+	plasmid stabilization protein	NA	NA	NA	NA
WP_009309981.1\|190080_190386_+	hypothetical protein	NA	NA	NA	NA
WP_016240375.1\|190411_190669_+	hypothetical protein	NA	NA	NA	NA
WP_009309982.1\|191668_192640_-	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	9.2e-150	86.3
WP_000523812.1\|192639_193806_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	3.0e-224	97.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP041515

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041515_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041515_1

729459-729585

Orphan

Consensus_repeat	Method
GTAGCCCTGCTAAGCGCAGCGCGAGCAGGGGATGTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041515_1

>merge|NZ_CP041515|1|729459-729585|CRISPRCasFinder
GTAGCCCTGCTAAGCGCAGCGCGAGCAGGGGATGTTTTCCCGGGTTGCGGCGTAAACGCCTTACCCGGGCTACCGGACCAGCACCGCCAGTAGCCCTGCTAAGCGCAGCGCGAGCAGGGGATGTTTT

>NZ_CP041515|1|1|729459-729585|CRISPRCasFinder
GTAGCCCTGCTAAGCGCAGCGCGAGCAGGGGATGTTTT	CCCGGGTTGCGGCGTAAACGCCTTACCCGGGCTACCGGACCAGCACCGCCA
GTAGCCCTGCTAAGCGCAGCGCGAGCAGGGGATGTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041515.1\|WP_025106514.1\|722155_722635_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|182325
NZ_CP041515.1\|WP_014837425.1\|726358_726895_-\|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl\|CDD\|185079
NZ_CP041515.1\|WP_025107362.1\|731131_731617_-\|type-II-secretion-system-protein-M	unknown	unknown	gnl\|CDD\|377391
NZ_CP041515.1\|WP_057173050.1\|735682_736888_-\|type-II-secretion-system-inner-membrane-protein-GspF	unknown	unknown	gnl\|CDD\|273980
NZ_CP041515.1\|WP_004098689.1\|725022_725478_-\|RNA-polymerase-binding-protein-DksA	unknown	unknown	gnl\|CDD\|182722
NZ_CP041515.1\|WP_064374753.1\|732795_733776_-\|type-II-secretion-system-minor-pseudopilin-GspK	unknown	unknown	gnl\|CDD\|377165
NZ_CP041515.1\|WP_064374752.1\|736889_738383_-\|type-II-secretion-system-ATPase-GspE	unknown	unknown	gnl\|CDD\|131585
NZ_CP041515.1\|WP_064374756.1\|730383_731142_-\|type-II-secretion-system-protein-N	unknown	unknown	gnl\|CDD\|376490
NZ_CP041515.1\|WP_014837424.1\|724080_724962_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP041515.1\|WP_004098709.1\|735239_735662_-\|type-II-secretion-system-major-pseudopilin-GspG	unknown	unknown	gnl\|CDD\|130771
NZ_CP041515.1\|WP_004098690.1\|725642_726359_-\|DNA/RNA-nuclease-SfsA	unknown	unknown	gnl\|CDD\|234733
NZ_CP041515.1\|WP_025106513.1\|720378_721233_-\|pantoate--beta-alanine-ligase	unknown	unknown	gnl\|CDD\|234741
NZ_CP041515.1\|WP_064374754.1\|731609_732803_-\|type-II-secretion-system-protein-GspL	unknown	unknown	gnl\|CDD\|273768
NZ_CP041515.1\|WP_049083165.1\|734727_735240_-\|type-II-secretion-system-minor-pseudopilin-GspH	unknown	unknown	gnl\|CDD\|225076
NZ_CP041515.1\|WP_064374758.1\|726967_729397_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|236950
NZ_CP041515.1\|WP_004098680.1\|721244_722036_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234723
NZ_CP041515.1\|WP_072065680.1\|722631_724029_-\|polynucleotide-adenylyltransferase-PcnB	unknown	unknown	gnl\|CDD\|236939
NZ_CP041515.1\|WP_048262356.1\|734365_734731_-\|type-II-secretion-system-minor-pseudopilin-GspI	unknown	unknown	gnl\|CDD\|376798
NZ_CP041515.1\|WP_004098675.1\|719904_720285_-\|aspartate-1-decarboxylase	unknown	unknown	gnl\|CDD\|180090
NZ_CP041515.1\|WP_047724421.1\|733772_734369_-\|type-II-secretion-system-minor-pseudopilin-GspJ	unknown	unknown	gnl\|CDD\|130772

Protein	Function_ID	Function_description	E-value
NZ_CP041515.1\|WP_025106514.1\|722155_722635_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|182325	PRK10239, PRK10239, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.	1.40324e-115
NZ_CP041515.1\|WP_014837425.1\|726358_726895_-\|RNA-2',3'-cyclic-phosphodiesterase	gnl\|CDD\|185079	PRK15124, PRK15124, RNA 2',3'-cyclic phosphodiesterase.	9.06738e-118
NZ_CP041515.1\|WP_025107362.1\|731131_731617_-\|type-II-secretion-system-protein-M	gnl\|CDD\|377391	pfam04612, T2SSM, Type II secretion system (T2SS), protein M. This family of membrane proteins consists of Type II secretion system protein M sequences from several Gram-negative (diderm) bacteria. The precise function of these proteins is unknown, though in Vibrio cholerae, the T2SM (EpsM) protein interacts with the T2SL (EpsL) protein, and also forms homodimers.	1.59029e-34
NZ_CP041515.1\|WP_057173050.1\|735682_736888_-\|type-II-secretion-system-inner-membrane-protein-GspF	gnl\|CDD\|273980	TIGR02120, Putative_general_secretion_pathway_protein_F, type II secretion system protein F. This membrane protein is a component of the terminal branch complex of the general secretion pathway (GSP), also known as the"Type II" secretion pathway. The GSP transports proteins (generally virulence-associated cell wall hydrolases) across the outer membrase of the bacterial cell. Transport across the inner membrane is often, but not exclusively handled by the Sec system. This model was constructed from the broader subfamily model, pfam00482 which includes components of pilin complexes (PilC) as well as other related genes. GspF is nearly always gene clustered with other GSP subunits. Some genes from Xylella and Xanthomonas strains score below the trusted cutoff due to excessive divergence from the family such that a sequence from Deinococcus which does not appear to be GspF scores higher. [Protein fate, Protein and peptide secretion and trafficking].	1.42595e-157
NZ_CP041515.1\|WP_004098689.1\|725022_725478_-\|RNA-polymerase-binding-protein-DksA	gnl\|CDD\|182722	PRK10778, dksA, RNA polymerase-binding protein DksA.	1.69645e-91
NZ_CP041515.1\|WP_064374753.1\|732795_733776_-\|type-II-secretion-system-minor-pseudopilin-GspK	gnl\|CDD\|377165	pfam03934, T2SSK, Type II secretion system (T2SS), protein K. Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.	9.23109e-87
NZ_CP041515.1\|WP_064374752.1\|736889_738383_-\|type-II-secretion-system-ATPase-GspE	gnl\|CDD\|131585	TIGR02533, Type_II_secretion_system_protein_E, type II secretion system protein E. This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP041515.1\|WP_064374756.1\|730383_731142_-\|type-II-secretion-system-protein-N	gnl\|CDD\|376490	pfam01203, T2SSN, Type II secretion system (T2SS), protein N. Members of the T2SN family are involved in the Type II protein secretion system. The precise function of these proteins is unknown.	4.17418e-37
NZ_CP041515.1\|WP_014837424.1\|724080_724962_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	8.20481e-154
NZ_CP041515.1\|WP_004098709.1\|735239_735662_-\|type-II-secretion-system-major-pseudopilin-GspG	gnl\|CDD\|130771	TIGR01710, Type_II_secretion_system_protein_G, type II secretion system protein G. This model represents GspG, protein G of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	4.52093e-65
NZ_CP041515.1\|WP_004098690.1\|725642_726359_-\|DNA/RNA-nuclease-SfsA	gnl\|CDD\|234733	PRK00347, PRK00347, DNA/RNA nuclease SfsA.	1.48175e-144
NZ_CP041515.1\|WP_025106513.1\|720378_721233_-\|pantoate--beta-alanine-ligase	gnl\|CDD\|234741	PRK00380, panC, pantoate--beta-alanine ligase; Reviewed.	1.19992e-163
NZ_CP041515.1\|WP_064374754.1\|731609_732803_-\|type-II-secretion-system-protein-GspL	gnl\|CDD\|273768	TIGR01709, Type_II_secretion_system_protein_L, type II secretion system protein L. This model represents GspL, protein L of the main terminal branch of the general secretion pathway, also called type II secretion. It transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	1.08384e-60
NZ_CP041515.1\|WP_049083165.1\|734727_735240_-\|type-II-secretion-system-minor-pseudopilin-GspH	gnl\|CDD\|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	5.84894e-09
NZ_CP041515.1\|WP_064374758.1\|726967_729397_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|236950	PRK11664, PRK11664, ATP-dependent RNA helicase HrpB; Provisional.	0
NZ_CP041515.1\|WP_004098680.1\|721244_722036_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl\|CDD\|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	4.27227e-160
NZ_CP041515.1\|WP_072065680.1\|722631_724029_-\|polynucleotide-adenylyltransferase-PcnB	gnl\|CDD\|236939	PRK11623, pcnB, poly(A) polymerase I; Provisional.	0
NZ_CP041515.1\|WP_048262356.1\|734365_734731_-\|type-II-secretion-system-minor-pseudopilin-GspI	gnl\|CDD\|376798	pfam02501, T2SSI, Type II secretion system (T2SS), protein I. The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. As members of the T2SJ family, members of the T2SI family are pseudopilins containing prepilin signal sequences.	4.70005e-22
NZ_CP041515.1\|WP_004098675.1\|719904_720285_-\|aspartate-1-decarboxylase	gnl\|CDD\|180090	PRK05449, PRK05449, aspartate alpha-decarboxylase; Provisional.	4.79081e-74
NZ_CP041515.1\|WP_047724421.1\|733772_734369_-\|type-II-secretion-system-minor-pseudopilin-GspJ	gnl\|CDD\|130772	TIGR01711, Type_II_secretion_system_protein_J, type II secretion system protein J. This model represents GspJ, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspI. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.	5.10746e-55

>NZ_CP041515.1|WP_064374758.1|726967_729397_+|ATP-dependent-helicase-HrpB
MSSLPVAAVLPELLSALQHAPQVLLNAPTGAGKSTWLPLQILAEGNINGRIILLEPRRLAARNVAQRLAELLGEKPGETVGYRMRAETCIGPNTRLEVVTEGILTRMIQRDPELSGVGLAILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLDNERLQRLLPEAPVIVSEGRAFPVERRFLPLPAHQRFDEAVAVAAAELLRSENGSMLLFLPGVGEIQRVQERLAERVASDVILCPLYGALPLSEQRKAILPAPAGMRKVVLATNIAETSLTIEGIRLVVDSAQERVARFDARTGLTRLVTQRISQASMTQRAGRAGRLEPGICLHLLAKEQAERAAAQGDPEILQSDLSSLLLELLQWGCQDPAQLSWLDLPPATNLAAARRLLTDLSALEGERLSAHGRKMAALGNDPRLAAMLTAAEDADGAATAAKLAAILEEPPRGGNSDLSAAFARQQGNWQQRAQQLMKRLAVRGGQPDADSIAALLASAFADRIAHRRGQEGRYQLANGMGAMLDADDALGRHEWLIAPLLLQGSASPDARILLALPVDIHALIEQCPALARRSDIVEWDEALGTLKAWRRTCIGRLVIKTQPLAKPSEEELHQAMLNGIREKGLSVLSWTPEAEQLRLRLHCAARWLPEEAWPAVDEASLLASLEQWLLPQMAGVHSLRALKALDVRQALQNWLPWPLRQKLDSELPTHYTVPTGSRIAIRYHDENPPALAVRMQEMFGEATTPTIAQGRVPLVLELLSPAQRPLQITRDLGAFWQGSYREVQKEMKGRYPKHVWPDDPANTAPTRRTKKYS
>NZ_CP041515.1|WP_014837425.1|726358_726895_-|RNA-2',3'-cyclic-phosphodiesterase
MSEPKRLFFAIELPGDVQQQIVHWRAASFPGDAGRPVAAANLHLTLAFLGEVSADKQRALSAMAGRIRQPGFTLTLDDAGQWLRSRVVWLGTRQPPRGVLQLANMLRAQAARSGCYQSPQPFHPHITLLRDARHAVPIPPPGFSWAFAVNEFVLYESSFSRGRTRYQALERYPFDKES
>NZ_CP041515.1|WP_004098690.1|725642_726359_-|DNA/RNA-nuclease-SfsA
MLFTPPLQSATLVKRYKRFLADVVTPDGRELTLHCPNTGAMTGCAAPGDTVWYSTSDNPKRKYAHTWELTETVEGATICVNTLRANTLAKEAILAGNIPELLGYNTLKSEVKYGDESSRIDILLQADDQQNCYIEVKSVTLAEKEYGYFPDAVTARGQKHLRELMSVAAAGDRAVILFAVLHSAIDRFSPAHHIDARYAQLLIEAQNKGVEILAYKAELSTEMMTLNKPITVVLTPGK
>NZ_CP041515.1|WP_004098689.1|725022_725478_-|RNA-polymerase-binding-protein-DksA
MQEGQNRKTSSLSILSIAGVEPYQVKPGEEYMNEAQLAHFKRILEAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDFGFCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
>NZ_CP041515.1|WP_014837424.1|724080_724962_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQNGIWRVRIEDIDPPREVPGAAETILRQLEHFGLHWDGEVLWQSKRHEAYRERLAWLREQGLCYYCTCTRARIHAIGGLYDGHCRDLRLGAENAALRLRQTRPVLEFYDQLRGTIVADEPLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQHFGWQAPDYIHLPLALNAQGNKLSKQNHAPALSTGDPRPEIVRALTFLNQDVIQEWQTLSIEDLLKYAVANWRPEQIQHSQMRSAEL
>NZ_CP041515.1|WP_072065680.1|722631_724029_-|polynucleotide-adenylyltransferase-PcnB
MFTRVANFCRKVLSREEREAEAAVEQLHMTVIPREQHAISRKDISENALKVMYRLNKAGYESWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGHTTDRVTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLQDGVIRLIGDPETRYREDPVRMLRAVRFAAKLGMSISEETAEPIPRLATLLHDVPPARLFEEVLKLLQAGDGYQTYLLLREYNLFQPLFPTITRYFTERGDSPMERIISQVLKNTDNRIRNDMRVNPAFLFAVMFWYPLLETAQKIAQESGLAYYDAFALAMNDVLDEACRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDLLELRAGAENSSELQRLTKWWGEFQVAAPPDQKDMLDDLGDDPAPRRRHRRPRKRAPRREGSA
>NZ_CP041515.1|WP_025106514.1|722155_722635_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MTLAYIAIGSNLASPLEQVNAAVNALAEIPDSRVISVSSFYRTPPLGPQDQPDYLNAAVALETSLAPEALLDHTQRIELQQGRTRKAERWGPRTLDLDIMLFGNEVINTPRLTVPHYDMQNRGFMLWPLFEIAPELCFPDGLALRDVLANLGAEKPASW
>NZ_CP041515.1|WP_004098680.1|721244_722036_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MKPTTIALLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTVQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLADLPFMAYATPEQTFENAAIVMRAGANMVKIEGGAWLADTVKMLAERAVPVCGHLGLTPQSVNVFGGYKIQGRGDAGQVLLDDALALEAAGAQLLVLECVPVELAKRVTEALTIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLSTAGDMRAAVRQYVAEVESGVYPGEEHSFH
>NZ_CP041515.1|WP_025106513.1|720378_721233_-|pantoate--beta-alanine-ligase
MLIIETLPLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDTAKASADVVVASIFVNPMQFDRAEDLARYPRTLQDDCEKLNKRKVDFVFAPAAAEIYSHGLENQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDFQQLALIRKMVADMGYDIEIIGVPIMRAKDGLALSSRNGYLSADQRKVAPGLYKVMNGAAEKLAAGERNLDEIIAIAAQELNEKGFRADDIQIRDADTLLDLTENSQRAVILMAAWLGEARLIDNQIVALVR
>NZ_CP041515.1|WP_004098675.1|719904_720285_-|aspartate-1-decarboxylase
MIRNMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIHIWNVTNGNRFSTYAIAAERGSRIISVNGAAAHCASVGDILIIASFVTMPDEEARTWQPKVAYFEGENEMKRQAKAIPVQVA
>NZ_CP041515.1|WP_064374756.1|730383_731142_-|type-II-secretion-system-protein-N
MKNKLTIALLLAAVYLFWLLFSAPARLLTLALPDGARLGETTGSLWQGEARQASWRGFDIAHLRWEFGFSSWLPGWHIAFNDPSGLRGQAWLHGLNDVVVREGRLAAPARTIGQRLASGIPLEARGQVVLTLPEARFNAGGCRQMTAGTVQWRDAALSSPAGSLELAQVNGKLSCTPAGALAVALTQDSRQLSLAGQGVLTPNGRYTFNGTLQTRQTAPALLTLLLAQNGRKDEQGRTPWQWQGQWRSGEKK
>NZ_CP041515.1|WP_025107362.1|731131_731617_-|type-II-secretion-system-protein-M
MDNLLALWQQRTRRERHLLLGMGVMLLIGLIYYAFWQPWQNREAQWRQTLAREQSSLRWMRQQTPLLQQLNQRKPSAAPEEPSTVIMREAGRHGIAIVRLQPQGSRLSLTVQPADFQALMAWLDALGQAGMTTATLAVTAVAQQPGWVTINTLVLERSDEK
>NZ_CP041515.1|WP_064374754.1|731609_732803_-|type-II-secretion-system-protein-GspL
MNNHHTFSAAVLIIRLNPDAATAIWRLAAPGDAAQTGEWHPDAGDPTLSLLAQRHPAWVLVPASDCAFHRVTLPAGARRNAQQALAFLLEEQLATEIEESHFALIHRDKSDCAVAVVGREKMRAWQAWCEGLGLNVLALTPDALALPQNPTGWSAVRCGEQWLFRCETCSGMAVETPWLGELLAHWPHIAPIACYSPPPDIAAPWQPRPAQDLLALAASNPQARKICLRQGNFAAKRRPPTPRRWRPAIVATLALLLLWSGNRLHDHLALARQADAAVQASRDFYRQWFKAEKNLVNPRLQMQQHLRRLESVSARPALISRLGALQQIIAETPGIRLRTLSYDAGRNALQLEISAVSSQALAQFSQRARAGFRVQTGEMKPRADGIEGRLTLEGNDG
>NZ_CP041515.1|WP_064374753.1|732795_733776_-|type-II-secretion-system-minor-pseudopilin-GspK
MNTRQRGVALLMVLLILALMMVLASAMTERSARMYQQTATTLDNLQAKWYALGAETLAAALLQRDALDSPNQTHLAQNWAQQGRRFAVNDGEIYATITDAQACFNLNAINQLSGDESVEIPYPAQVFTRLLENLGSEPLRALQLTAALRDWVDSDRQALLNGAEDEAYMAQSPGYLTGNQPLQDVSELRLLAGMDAALYQRLLPYVCALADETLQVNVNTLQPAQAALLAALFPAELTLAEARQLLQARAATGWSSVAAFLSQPLLQKTDTAAARPWLAVHSERFIATFSVVMGSARYQQRSLLQKQGRTFSVVQRRYGIYWVADE
>NZ_CP041515.1|WP_047724421.1|733772_734369_-|type-II-secretion-system-minor-pseudopilin-GspJ
MIQRARGFTLVEMLLALAILAALSVAAVTVLQNVMRADTLTRDKGGRMQALQLTFSQMAADFSQIIPRRSRDSASLFFAGRFQLGSDDWAIAFSRNGWPNPLGILPRSEIQNVSYRLRGDRLERLSYDQQDPLPGSLPTVTVMQRNVQAFRLRFYASGRWQDEWQQTQTLPQGLEVTLTLEQSGEIRRLFLLTPGGSQ
>NZ_CP041515.1|WP_048262356.1|734365_734731_-|type-II-secretion-system-minor-pseudopilin-GspI
MKKQAGMTLIEVMVALAVFALAGLAVMQATLQQTRQLGRMEEKTLAGWLADNQLVQLRLENRWPALSWSETMVQAAGVSWHIRWQGVETDLPQLRALDVEVRRAKSDKMPVSSLRTYVTPP
>NZ_CP041515.1|WP_049083165.1|734727_735240_-|type-II-secretion-system-minor-pseudopilin-GspH
MRQRGFTLLEMMLILLLIGVSAGMVMLAFPASRDDSAAQALARFEAQLRFVQQRGLQTGQFFGASVHPDRWQFLVLQPRESNDPPPAGDDWNGYRWLPLRAGRVATSGSVAGNTLHLTFPQGEAWTPGDNPDVLIFPGGEMTPFRLTVGEGPGIAFNARGESLPEPQEAP
>NZ_CP041515.1|WP_004098709.1|735239_735662_-|type-II-secretion-system-major-pseudopilin-GspG
MQRQRGFTLLEIMVVIVILGVLASLVVPNLMGNKEKADRQKVVSDLVALEGALDMYKLDNSRYPTTEQGLQALVSAPSAEPHARNYPEGGYIRRLPQDPWGSDYQLLSPGQHGQVDIFSLGPDGVPESNDDIGNWTIGKK
>NZ_CP041515.1|WP_057173050.1|735682_736888_-|type-II-secretion-system-inner-membrane-protein-GspF
MALFRYQAVDENGKTRRGVQQADSARHARQLLREKGWLALDIAPAAGSGGQLRFIRRTNARDLALVTRQLATLVAAAIPLEKALDAVAQQCEKNQLKTLIAGVRGKVLEGHSLAEAMRGYPGCFDALYCAMVAAGEASGHLDGVLNRLADYTEQRQQLRARLLQAMIYPIVLTLVAVSVIVILLSTVVPKVVEQFIHLKQALPFSTRLLMAMSDVLRAAGPWLLLAAMLIALLLRYLLRQPAKRLAWHRLLLRLPLIGRVARSVNSARYARTLSILNASAVPLLLAMRISAEVLSNAWAKRQLEAASDAVREGVSLHRALEMTQLFPPMMRYMVASGEQSGELNGMLERAADNQDRDLSAQIQLALSLFEPLLIVAMAGMVLFIVLAILQPILQLNTLMSM
>NZ_CP041515.1|WP_064374752.1|736889_738383_-|type-II-secretion-system-ATPase-GspE
MTPAAERRPLLPFAYARAHNVMLLSNGESCEVFCLAATAPQALLEARRVAGMPFSLERLEAEAFEKLLVLSYQRDSAEARRMMADIGNELDLYTLAEELPDTDDLLDSEDDAPIIRLINAMLTEAIKEKASDIHIETYERHLQIRFRVDGVLREILRPQRRLAALLISRIKVMASLDIAEKRIPQDGRMALRIGGRAVDVRVSTLPSSYGERVVLRLLDKNSVNLDLLTLGMSPALLQQVDGLIARPHGIVLVTGPTGSGKSTTLYAALSRLDARERNIMTIEDPIEYELEGIGQTQVNAKVDMTFARGLRAILRQDPDVVLVGEIRDGETAQIAVQASLTGHLVLSTLHTNSALGAISRLQDMGVEPFLLSTSLLAVMSQRLVRRLCPLCRQQEPANADTARQMEIAPGTALWQPRGCAECGFTGYRGRTGIHELLLVDDRVRMAIHRGENEVTLIQQLGADYITLRHAGRDKALAGITSWQEVLRVSEQQIAEAS

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Crispr_ID: NZ_CP041515_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041515_2

5660583-5660673

Orphan

Consensus_repeat	Method
CCGCCTGCGATCGGGTAGCCCGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041515_2

>merge|NZ_CP041515|2|5660583-5660673|CRISPRCasFinder
CCGCCTGCGATCGGGTAGCCCGGATAAGGCGACAGCCGCCATCCGGGGGATTCAATCCGCTTCACAGCCGCCTGCGTTCGGGTAGCCCGGA

>NZ_CP041515|2|2|5660583-5660673|CRISPRCasFinder
CCGCCTGCGATCGGGTAGCCCGGA	TAAGGCGACAGCCGCCATCCGGGGGATTCAATCCGCTTCACAG
CCGCCTGCGTTCGGGTAGCCCGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041515.1\|WP_032751845.1\|5652442_5653396_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|181818
NZ_CP041515.1\|WP_014839827.1\|5665822_5667187_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NZ_CP041515.1\|WP_064375676.1\|5668564_5669467_+\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NZ_CP041515.1\|WP_025107590.1\|5660717_5661134_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP041515.1\|WP_025107596.1\|5654905_5655766_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP041515.1\|WP_025107592.1\|5658277_5659774_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP041515.1\|WP_025107593.1\|5657456_5658077_-\|phosphatase	unknown	unknown	gnl\|CDD\|226105
NZ_CP041515.1\|WP_025107597.1\|5654359_5654914_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
NZ_CP041515.1\|WP_014227296.1\|5667237_5668404_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP041515.1\|WP_064375678.1\|5653410_5654190_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|225130
NZ_CP041515.1\|WP_064375675.1\|5672633_5673599_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|182167
NZ_CP041515.1\|WP_143444515.1\|5661587_5662712_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|184990
NZ_CP041515.1\|WP_032751836.1\|5662711_5665819_+\|multidrug-efflux-RND-transporter-permease-subunit-EefB	unknown	unknown	gnl\|CDD\|273335
NZ_CP041515.1\|WP_014227281.1\|5651396_5652446_+\|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176186
NZ_CP041515.1\|WP_014227287.1\|5656855_5657326_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|377770
NZ_CP041515.1\|WP_064375677.1\|5659854_5660502_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP041515.1\|WP_048262922.1\|5669491_5670925_+\|PTS-N-acetylmuramic-acid-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|181971
NZ_CP041515.1\|WP_014227298.1\|5671030_5671267_+\|type-II-toxin-antitoxin-system-CcdA-family-antitoxin	unknown	unknown	gnl\|CDD\|377822
NZ_CP041515.1\|WP_014227299.1\|5671269_5671578_+\|CcdB-family-protein	unknown	unknown	gnl\|CDD\|376629
NZ_CP041515.1\|WP_025107595.1\|5655790_5656600_-\|lipoprotein-NlpA	unknown	unknown	gnl\|CDD\|182119

Protein	Function_ID	Function_description	E-value
NZ_CP041515.1\|WP_032751845.1\|5652442_5653396_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.38791e-105
NZ_CP041515.1\|WP_014839827.1\|5665822_5667187_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	6.39623e-100
NZ_CP041515.1\|WP_064375676.1\|5668564_5669467_+\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	1.87241e-174
NZ_CP041515.1\|WP_025107590.1\|5660717_5661134_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.06375e-10
NZ_CP041515.1\|WP_025107596.1\|5654905_5655766_-\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.87809e-13
NZ_CP041515.1\|WP_025107592.1\|5658277_5659774_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.16335e-70
NZ_CP041515.1\|WP_025107593.1\|5657456_5658077_-\|phosphatase	gnl\|CDD\|226105	COG3576, COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase [General function prediction only].	4.23803e-13
NZ_CP041515.1\|WP_025107597.1\|5654359_5654914_+\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	4.18561e-36
NZ_CP041515.1\|WP_014227296.1\|5667237_5668404_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.76372e-84
NZ_CP041515.1\|WP_064375678.1\|5653410_5654190_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|225130	COG2220, COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only].	8.46226e-18
NZ_CP041515.1\|WP_064375675.1\|5672633_5673599_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	1.07981e-145
NZ_CP041515.1\|WP_143444515.1\|5661587_5662712_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|184990	PRK15030, PRK15030, multidrug efflux RND transporter periplasmic adaptor subunit AcrA.	3.41667e-111
NZ_CP041515.1\|WP_032751836.1\|5662711_5665819_+\|multidrug-efflux-RND-transporter-permease-subunit-EefB	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NZ_CP041515.1\|WP_014227281.1\|5651396_5652446_+\|NAD(P)-dependent-alcohol-dehydrogenase	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP041515.1\|WP_014227287.1\|5656855_5657326_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|377770	pfam07080, DUF1348, Protein of unknown function (DUF1348). This family consists of several highly conserved hypothetical proteins of around 150 residues in length. The function of this family is unknown.	5.44062e-96
NZ_CP041515.1\|WP_064375677.1\|5659854_5660502_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.90275e-14
NZ_CP041515.1\|WP_048262922.1\|5669491_5670925_+\|PTS-N-acetylmuramic-acid-transporter-subunit-IIBC	gnl\|CDD\|181971	PRK09586, murP, PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed.	0
NZ_CP041515.1\|WP_014227298.1\|5671030_5671267_+\|type-II-toxin-antitoxin-system-CcdA-family-antitoxin	gnl\|CDD\|377822	pfam07362, CcdA, Post-segregation antitoxin CcdA. This family consists of several Enterobacterial post-segregation antitoxin CcdA proteins. The F plasmid-carried bacterial toxin, the CcdB protein, is known to act on DNA gyrase in two different ways. CcdB poisons the gyrase-DNA complex, blocking the passage of polymerases and leading to double-strand breakage of the DNA. Alternatively, in cells that overexpress CcdB, the A subunit of DNA gyrase (GyrA) has been found as an inactive complex with CcdB. Both poisoning and inactivation can be prevented and reversed in the presence of the F plasmid-encoded antidote, the CcdA protein.	8.08152e-21
NZ_CP041515.1\|WP_014227299.1\|5671269_5671578_+\|CcdB-family-protein	gnl\|CDD\|376629	pfam01845, CcdB, CcdB protein.	9.48804e-43
NZ_CP041515.1\|WP_025107595.1\|5655790_5656600_-\|lipoprotein-NlpA	gnl\|CDD\|182119	PRK09861, PRK09861, lipoprotein NlpA.	0

>NZ_CP041515.1|WP_064375677.1|5659854_5660502_+|TetR/AcrR-family-transcriptional-regulator
MSAQKDNEAPRRPGRPRGQKSGSANREQLMDIALALFARHGIARISLNAIAKEAGVTPAMLHYYFSSREALVEKLVEERFMPLRSEIGQIFVAHGDDPVTAFTLLIETLAAMAEKNAWFAPLWMQEIIGEMPVLRQHMHARFGDQKYHKMLETVRRWQREGKLNPALSPELLFTTLISLVLVPFSRTHTDPRLQSVDRKMIVSHALTLIGRGIGG
>NZ_CP041515.1|WP_025107592.1|5658277_5659774_-|MFS-transporter
MTSEIASQPAVPSIRLLFSALLLVMLLSALDQTIVSTALPTIVGELGGLDKLSWVVTAYILSSTIAVPLYGKFGDLFGRKIVLQVAIVLFLAGSALCGLAQNMTQLVLMRGLQGLGGGGLMVISMAAVADVIPPANRGRYQGLFGGVFGLATVIGPLIGGFLVQHASWRWIFYINLPLGLFALLVIGAVFHSSNKRSQHQIDWLGAIYLSMALLCIILFTSEGGSVRAWSDPQLWCILAFGLVGIVGFIHEERLASEPIIPLSLFRNRSFLLCSLIGFVIGMALFGSVTFLPLYLQVVKEATPTEAGLQLIPLMGGLLLTSIVSGRIISRTGKYRVFPIIGTLLGVVGMVLLTRITIHSAMWQLYLFTGVLGAGLGLVMQVLVLAVQNAMPAQMYGVATSGVTLFRSIGGSIGVALFGAVFTHVLQSNLQRLLPEGAQLPRTLNPAAVQNLPAEIRLDYLDAFGSAIHAAFLMAACIMAVAFALSWLLKEAPLKTGTR
>NZ_CP041515.1|WP_025107593.1|5657456_5658077_-|phosphatase
MPAEFLDIAMTPDVMDVQHEMGSDELWQSPHRQRRGERFGASEEAMIATRDSFYLATLSQTGWPYIQHRGGPVGFLHLLDETTLAMADFSGNRQYITTGNLRGSDRACLFLMDYPRRARLKIYATVEVVAVDADPQLLAQVAPENYRARIERIYRFHLQAFDWNCPQHITPRYTARQVAEYSQTLQQRIDELERENQRLQQLIYPK
>NZ_CP041515.1|WP_014227287.1|5656855_5657326_-|nuclear-transport-factor-2-family-protein
MTEQRPPLPPFTRESAAQKVRAAEDGWNSRDAAKVALAYTVESEWRNRSEFVHGRTQIIDFLQRKWRKEQEYRLIKELWAWSDNRIAVRFAYEWHDDSGNWFRSYGNENWEFDEHGLMQTRYACINDLPITESERLFHWPQGRRPDDHPGLSELGL
>NZ_CP041515.1|WP_025107595.1|5655790_5656600_-|lipoprotein-NlpA
MKLRLRTAAAVVLAGLLLAGCDQKGSDAKHIKVGVINGAEQDVAEVAKKVAKEKYGLDVELVGFSGSLLPNESTNAGDLDANVFQHRPFLEQDNKAHNYRLVAVGNTFVFPMAGYSRKIKSVAELKDGATIAIPNDPTNLGRALLLLQQEKLITLKAGTGLLPTAVDIIDNPHHLKIMELEGAQLPRVIDDPKVDVAIISTTYLQQTGLSPVRDGIFIEDKNSPYVNIIVTREDNKDAENVKAFIQSYQSPEVAKAAETIFNGGAVPGW
>NZ_CP041515.1|WP_025107596.1|5654905_5655766_-|EamA-family-transporter
MTRQRQADLLLIAATVIAACGWIFSREAIAGMPVFAFLGLRFFFAALLLLPFCRGLRVERQQWPRMIISGLWFALNLCLWIYSVSTTPSLGEGAFIMSLSMLFVPLTAWVMMKARPARAYWECLPIAIVGLGLLSLHMPIAFHPSQGWFLLTALVQSIWFCYTSKSAREVPLIPLTTVQLGITGIVGLGISAAVESWTQPFTLPTFGWLLASIVIATSLRFGLQMKGQKYAAVASAAIIMVLEPLLTVIAAALWYGEQLPLQKIIGGLLILVAQLWFRWRMLKPLR
>NZ_CP041515.1|WP_025107597.1|5654359_5654914_+|NUDIX-hydrolase
MKKKLTSADMHDVEVLADTPWFSMRKVGIDMAPGDRRDFYSIHYPRPAVGIVAMQDDKVLLIRHYRYLIDRVVWAIPSGGVDEGEDPRAAALRELREETGWQAQRADEIIRYNPSYGSSDQLFITWLAHDLTWVGMDEDQDEVMETGWFTLEEIGQLIARGEMPDGLSLVPLLHLMAQRRTGLA
>NZ_CP041515.1|WP_064375678.1|5653410_5654190_-|MBL-fold-metallo-hydrolase
MKITHVRNATQLIDYAGKKFLIDPMLSAKGAWAGFAGTARSELRNPLVELPFSIETIVDVDAVIVTHTHQDHWDEAAIAAIPKTLPVYVQHDADGQLLRGQGFCDIRLLSEDSAFADVALVKTTSGQHGSDRTYAVPAMAERLGEACGVVLRHPQEKTLWLVGDTIWRDAVEADMLRLRPDVVVLNAGYAHVIGFGPIIMGKEDVLKAHFVLPEAKIVASHMDAVNHCLLSRDELRQYVADNQIAEAVSIPQDGESMVF
>NZ_CP041515.1|WP_032751845.1|5652442_5653396_-|helix-turn-helix-domain-containing-protein
MKLTEVAIVAVDGFSPFHYSVPCMLFGDTVSETKRFNLHICAERPGLLSARDGFALNASGDFSLLAQADIVVVPYWGAVNQRPPQPLLDGLVRARNNGAQIVGLCLGAFVLGYAGLLDDRRAATHWEFEQDFQRLFPQVRLDINALYVDDEGIITSAGTAAALDCCLYLIRQRFGSLVANQIARRMIVPPHREGGQAQFIAQPVPKNTRDARINGLLEYLQQHIREPHNLDSLAQVAAMSRRTLTRHFAKATGMGIADWLAAERLRRSQILLEAGDLPVGQVAEEVGYRSAVTWRQQFKARFGVSPAEWRRTFRRGA
>NZ_CP041515.1|WP_014227281.1|5651396_5652446_+|NAD(P)-dependent-alcohol-dehydrogenase
MQINAIGTNSASQPLGSMAITRREPGPDDVQIAIDYCGVCHSDVHQARSEWAGTLYPCVPGHEIVGRVTAVGSRVSGHAVGDLVGVGCMVDSCKECEECRDGLENYCDRMVLTYNGPTQDAPGHTLGGYSQQIVVHQRYVLRVRHPKEQLAAVAPLLCAGITTYSPLRHWNVGPGKKVGIVGIGGLGHMGIKLAHAMGAHVVAFTTSESKRDAARELGADEVVVSRNENEMAAHLKSFDFILNTVAAPHNLDAFTTLLKRDGTMTLVGAPATPHPSPEVFNLIFRRRSIAGSMIGGIPETQEMLDFCAEHGIVADIELIRGDQINEAWERMIKGDVKYRFVIDSATLGG
>NZ_CP041515.1|WP_025107590.1|5660717_5661134_-|GNAT-family-N-acetyltransferase
MTLIITENINPADQEELLAGLREYNLRFLDPAQFGELGVYSRDDAGAMRGGLIGKRKGSWLCIDYLWVSEASRGSGLGSELMHEAENQARARGCSHVLVDTFSFQALPFYQKLGYQLQMSLPDFPHVGMQRHYLSKVL
>NZ_CP041515.1|WP_143444515.1|5661587_5662712_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKYTLAPIAAALFLLSGCDNAQNASPQQMTQEVGVVTLHGQPVPVVSSLTGRTTASLSAEVRPQVGGIVQKRLFTEGDMVKAGQALYQIDPSSYRATFNEAAASLKQAQALVIADCQKAQRYAVLVKDNGVSRQDADDAIATCNQDKASVESKKAALESARINLNWTTVTAPIAGRIGISSVTPGALVSADQDTALATIRGLDTMYVDLTRSSVDLLRLRKQSLASNSDTLNVTLTLEDGSTYSEKGRLALTEVAVDESTGSVTLRAVFPNPQHVLLPGMFVRACIDEGIMNDAILAPQQGITRDAKGDATALVVDANNKVEQRSVETGETYGDKWLIVNGLKSGDRLIVEGTGKVAPGQQVKAAEVKNDGGNA
>NZ_CP041515.1|WP_032751836.1|5662711_5665819_+|multidrug-efflux-RND-transporter-permease-subunit-EefB
MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPAIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFTSTSSSDGSVSITVTFEQGTDPDTAQVQVQNKVQQAESRLPSEVQQSGVTVEKSQSSFLLILAVYDKNNKATSSDISDWLVSNMQDPMARIEGVGSLQVFGAEYAMRIWMDPTKLASYSLMPSDVQSAIEAQNVQVSAGKIGALPASNAQQLTATVRAQSRLQTVAQFKEIIVKSKSDGSVVRLSDVARVEMGSEDYTASANLNGHPAAGIAVMMAPGANALNTATLVKNKIAEFQRQMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIILVVCVMYLFLQNFRATLIPAVAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALIAIALVLSAVFLPMAFFGGSTGVIYRQFSVTIISAMMLSVVVALTLTPALCGALLSHSKPHTKGFFGAFNRLWGRTEQGYQHRVVGGLRRSAMMMGAFVLICGGMALAMWKLPGSFLPTEDQGEIMVQYTLPAGATAVRTAEVRRQVTDWFLTKEKANTDVIFTVDGFSFSGSGQNAGMAFVSLKNWSERKGEENTAQAIALRATKELGSIRDATLFAMTPPSVDGLGQSNGFTFELMASGGTDRDSLMKMRSQLLAAANQSTELQSVRANDLPQMPQLQVDIDNNKAVSLGLSLSDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGESDARAVPSDLGKWFVRGSDDSMTPFSAFATTRWQYGPESLVRYNGSAAFEIQGENASGFSSGAAMDKMEALANNLPAGTTWAWSGMSLQEKLASGQAMSLYAISILVVFLCLAALYESWSVPFSVIMVIPLGLLGAALAAWMRGLSNDVYFQVALLTTIGLSSKNAILIVEFAESAVEEGYSLSRAAMRAAQTRLRPIVMTSLAFIAGVLPLAIATGAGANSRVAIGTGIIGGTLTATLLAVFFVPLFFVLVKRFFTRHRSSQE
>NZ_CP041515.1|WP_014839827.1|5665822_5667187_+|efflux-transporter-outer-membrane-subunit
MFRFTLVFVALLTAGCVSLDPHYERPAAPVPATLPGSHGEATAVVSDWQQVVNDARLKKVVNIALTSNRDVQKALADIEAARAQFGETRASLFPTLDAELSHTRSKTVASGLTSSAEADGAVSSFELDLFGKNQSLTRAARETWLASEFTAQNTRLTMIADLTTAWITLAADNSNLALAQDTMASAENSRRIVTRQMEVGTASAGDLSDAESVYQQARASVASYRTLVAQDKNALNLLAGETVPDSLLPGTLESLGDRSITLVPAGVSSSVLLRRPDIQEAEHNLKSANADIGAARANFFPSISLTASAGVGSDSLSSLFSHGMQVWSFAPSISLPLFTGGSNLAQLRYAEAEKKGLIATYEKTIQSAFKDVADALARRETLSEQLDAQNKYVAAEQKSLNIAMKSYQAGVGDYLSVLTAQRTLWSAQATLISLQQTDLENRITLWQSLGGGAS
>NZ_CP041515.1|WP_014227296.1|5667237_5668404_+|multidrug-effflux-MFS-transporter
MSRISLSWVVVLGLLSAIGPLCTDFYLPALPEITQQLSATGTQTQLSLTAALIGLGLGQLFFGPLSDRIGRKKPLALSLLLFIFSSAMCAITYDIHMLIAWRFLQGFAGAGGSVLSRSIARDRYQGTLLTQFFALLMTVNGIAPVLSPVLGGWIITAFDWRILFWAMAAIGVVLLLLSLTVLHETLPAKSAASATRQQADAPVLKNRRFMRYCLIQAFMMAGLFSYIGSSSFVIQSEYAMSAMQFSLLFGLNGIGLIIAALIFSRLARRFSAEALLRGGQLLAVAFAAITLLFAWLPQPTLALVGLFFTVSMMSGISTVAGSEAMNAIHARQSGTASALMGTLMFVFGGIAAPLAGLGGETMLKMSFAMTLCYLAALLIGLKKPRPIA
>NZ_CP041515.1|WP_064375676.1|5668564_5669467_+|N-acetylmuramic-acid-6-phosphate-etherase
MSIDLSKLLTERRNANSANIDILTTEEMLTVINQEDQQVAHAITPYLPQIAQVVDKVAAALQAGGRLIYIGAGTSGRLGILDASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKAQGAMDLQNLNFSSRDVLVGLAASGRTPYVIGAMEYAHSQNAFVAIVSCNPHGEMAQLADVAITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRIGKVYSNLMVDVEATNAKLIERQVSIVMEATECDRATAQSALEACDRYCKTAIVMVLADLSAADAQALLAKNNGYIRKALSHS
>NZ_CP041515.1|WP_048262922.1|5669491_5670925_+|PTS-N-acetylmuramic-acid-transporter-subunit-IIBC
MAKINKEMIARILQHVGGAGNVAQAGNCMTRLRLTLRDESRADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQSAAEMMNALLEEAPADAPSLADVAAEKKQALKSKQTSGIQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQIFVLENAHPNATLMALIGYMKVFSKGMFTFLSILIGYNAQKAFGGSGVNGAIIAALFVLGYNPEATSGFYSGISTFFGHGIDPRGNIIGVLIAAIIGAWVERQVRRIMPANLDMILTSAVTLLIMGAITFTVIMPIGGWLFTGMSWLFLHLNGNPFGSAVLAGLFLLAVMFGVHQGFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAKHGSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFITACLGGACGGFFLGLVAWMGLPVGLNTVFGPSGLVALPLMTSGSGIYAGMAVYAAGLAVSYLCGFALTWLFGSKNVDLS
>NZ_CP041515.1|WP_014227298.1|5671030_5671267_+|type-II-toxin-antitoxin-system-CcdA-family-antitoxin
MPAAKRNKQNVSVTLDPGLVKQAREVGINLSLTLTNALKSEIHSLEIARWQKENAQAIDYLNNLTEENGLLSDEYRTF
>NZ_CP041515.1|WP_014227299.1|5671269_5671578_+|CcdB-family-protein
MQYYVYKNTGRIAAYPYLLDVQSDIIGKRNTRVVIPLFPLKNYKGPRADRLTPLVTVEGEEYVVMTHELASIPHRVLGEEVCNLNHQREVVKASMDFLFDGI
>NZ_CP041515.1|WP_064375675.1|5672633_5673599_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MTQKGTPSTPHDAVFKQFLSHPECARDFIEIHLPAPLRQLCNLQTLKLESGSFIEADLCASYSDVLWSLKTRDGDGYIYVVIEHQSTPEAHMAFRLMRYALAAMQRHLDAGHKTLPLVVPMLFYHGAKSPYPFSLCWLDEFTDTQTARRLYAAAFPLVDITVVPDDEIMQHRRVALLELIQKHIRQRDLLGLVERLAELLVKGCANDSQLKALFNYMLQCGDAPHFGEFLHEVERRVPQHKEVLMTIAERLRQEGRQEGKLEGKLEGKLEGKQEGRQEEALRIARSLLEQGFERELVQVACELSDDDLKMLQTQVAASPGR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP041515_1	1.1\|729497\|51\|NZ_CP041515\|CRISPRCasFinder	729497-729547	51	LR134122	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2	454344-454394	9	0.824

1. spacer 1.1|729497|51|NZ_CP041515|CRISPRCasFinder matches to LR134122 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2) position: , mismatch: 9, identity: 0.824

cccgggttgcggcgtaaacgccttacccgggctaccggaccagcaccgcca---	CRISPR spacer
cccgggtagcggcgtaaacgccttacccgggctactgg---agagcagacattt	Protospacer
******* ***************************.**   ** .* * **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1124829 : 1237812

114

Escherichia_phage(20.0%)

integrase,protease,transposase,tail,tRNA,holin

attL 1162768:1162783|attR 1223339:1224537

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143444305.1\|1124829_1125753_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	6.6e-65	52.0
WP_014228211.1\|1125819_1125993_-	pleiotropic regulatory protein RsmS	NA	NA	NA	NA
WP_064374554.1\|1126007_1126535_-	primosomal replication protein N''	NA	NA	NA	NA
WP_004848353.1\|1126604_1126982_+	DUF454 family protein	NA	NA	NA	NA
WP_004099669.1\|1127132_1127684_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.3e-28	45.2
WP_064374555.1\|1127775_1129683_+	DNA polymerase III subunit gamma/tau	A0A1L2BWV7	Bacteriophage	2.3e-43	38.2
WP_004099673.1\|1129740_1130073_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_004129946.1\|1130072_1130678_+	recombination protein RecR	NA	NA	NA	NA
WP_009653565.1\|1130789_1132664_+	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	5.6e-111	36.3
WP_004848363.1\|1132852_1133497_+	adenylate kinase	NA	NA	NA	NA
WP_004129953.1\|1133624_1134587_+	ferrochelatase	NA	NA	NA	NA
WP_004137947.1\|1134650_1135955_+	inosine/guanosine kinase	NA	NA	NA	NA
WP_064374556.1\|1135998_1137660_-	Kef family K(+) transporter	NA	NA	NA	NA
WP_004848370.1\|1138017_1139238_-	MFS transporter	NA	NA	NA	NA
WP_014228215.1\|1139401_1141054_+	bifunctional UDP-sugar hydrolase/5'-nucleotidase	NA	NA	NA	NA
WP_014228216.1\|1141182_1141662_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_046876973.1\|1141863_1142658_-	conjugal transfer protein TraB	NA	NA	NA	NA
WP_025107137.1\|1142980_1143388_+	biopolymer transporter ExbD	NA	NA	NA	NA
WP_064374557.1\|1143389_1144133_+	TonB family protein	NA	NA	NA	NA
WP_014228220.1\|1144167_1146408_+	TonB-dependent receptor	NA	NA	NA	NA
WP_004137930.1\|1146427_1147075_+	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_025107135.1\|1147067_1148318_+	phospholipase	A0A1B1MR92	Pteropox_virus	1.2e-24	22.4
WP_064374559.1\|1148392_1150894_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	1.4e-114	38.1
WP_048261479.1\|1151000_1151411_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_064374560.1\|1151407_1151872_-	NfeD family protein	NA	NA	NA	NA
WP_004129981.1\|1151868_1152786_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_004848402.1\|1152922_1153603_+	iron ABC transporter ATP-binding protein FetA	G3M9Y6	Bacillus_virus	3.2e-24	34.3
WP_004129987.1\|1153589_1154372_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_014228228.1\|1154480_1155335_-	co-chaperone YbbN	NA	NA	NA	NA
WP_049084602.1\|1155396_1156167_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_072351673.1\|1156195_1156822_-\|protease	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	NA	NA	NA	NA
WP_004099723.1\|1156789_1157476_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.6e-34	36.5
WP_032748326.1\|1157472_1159890_+	ABC transporter permease	NA	NA	NA	NA
WP_014228233.1\|1159958_1160267_-	monooxygenase	NA	NA	NA	NA
WP_004130005.1\|1160476_1161622_+	porin	NA	NA	NA	NA
WP_032719617.1\|1161739_1162819_-\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
1162768:1162783	attL	NA	NA	NA	NA
WP_014228235.1\|1163024_1164092_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
1162768:1162783	attL	NA	NA	NA	NA
WP_064374561.1\|1164088_1164598_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_025107126.1\|1164879_1165602_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_004099775.1\|1165605_1166100_-	peptidylprolyl isomerase B	NA	NA	NA	NA
WP_004848430.1\|1166273_1167659_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.0e-45	35.1
WP_025107125.1\|1167953_1168166_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004099791.1\|1168167_1169034_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	6.5e-30	34.8
WP_065806339.1\|1169625_1170837_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	3.1e-131	58.5
WP_074423280.1\|1170962_1171253_+	hypothetical protein	NA	NA	NA	NA
WP_080490680.1\|1172092_1172872_+	hypothetical protein	NA	NA	NA	NA
WP_047683739.1\|1172946_1173429_+	hypothetical protein	NA	NA	NA	NA
WP_143444306.1\|1174526_1175198_+	hypothetical protein	NA	NA	NA	NA
WP_139155936.1\|1175221_1175500_+	hypothetical protein	NA	NA	NA	NA
WP_021314389.1\|1176896_1178177_-	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_031285560.1\|1178343_1180527_-	1,4-alpha-glucan branching enzyme	NA	NA	NA	NA
WP_021314392.1\|1181497_1182622_-	ABC transporter permease	NA	NA	NA	NA
WP_021314393.1\|1182621_1185351_-	ribosome-associated ATPase/putative transporter RbbA	A0A2H4PQG7	Staphylococcus_phage	4.6e-21	30.6
1183902:1183917	attR	NA	NA	NA	NA
WP_028016386.1\|1185347_1186415_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
1183902:1183917	attR	NA	NA	NA	NA
WP_021314398.1\|1188214_1188778_+	hypothetical protein	NA	NA	NA	NA
WP_115723444.1\|1188774_1189619_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	4.0e-24	50.9
WP_021314400.1\|1189852_1190083_+	YgdI/YgdR family lipoprotein	NA	NA	NA	NA
WP_021314401.1\|1190370_1190613_-	YfdY family protein	NA	NA	NA	NA
WP_031285562.1\|1191120_1192152_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_101827254.1\|1193328_1194345_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7
WP_143444307.1\|1194362_1195196_+	DUF932 domain-containing protein	A0A2C9CX26	Yersinia_phage	9.9e-44	37.3
WP_087776359.1\|1195219_1195450_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_065805885.1\|1195529_1195973_+	antirestriction protein	A0A2D0W9W4	Bordetella_phage	3.9e-15	35.2
WP_065805886.1\|1195984_1196464_+	DNA repair protein RadC	NA	NA	NA	NA
WP_065805887.1\|1196477_1196699_+	DUF987 domain-containing protein	NA	NA	NA	NA
WP_065805888.1\|1196723_1197083_+	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_065805889.1\|1197139_1197529_+	toxin CbtA	NA	NA	NA	NA
WP_065805890.1\|1197615_1198461_+	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_032434112.1\|1198628_1199792_-\|integrase	site-specific integrase	G8C7S0	Escherichia_phage	1.1e-202	86.8
WP_071531921.1\|1199668_1200004_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_009483816.1\|1200005_1200224_-	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	2.6e-12	52.2
WP_064838834.1\|1200220_1200496_-	hypothetical protein	A0A1U8QJU8	Salmonella_virus	1.9e-23	59.5
WP_040217347.1\|1200982_1201327_-	hypothetical protein	NA	NA	NA	NA
WP_057774652.1\|1201361_1202471_-	recombinase RecT	H6WRX0	Salmonella_phage	3.6e-182	85.6
WP_130949577.1\|1202483_1205582_-	exodeoxyribonuclease	H6WRX1	Salmonella_phage	2.5e-294	57.2
WP_022631175.1\|1205719_1205875_-	DNA breaking-rejoining protein	K7PGY4	Enterobacteria_phage	1.5e-14	71.2
WP_130949578.1\|1205883_1206075_-	DUF1482 family protein	NA	NA	NA	NA
WP_022631176.1\|1206181_1206280_-	hypothetical protein	NA	NA	NA	NA
WP_004190711.1\|1206371_1206680_-	hypothetical protein	G8C7T6	Escherichia_phage	1.7e-25	62.2
WP_020805737.1\|1206963_1207167_+	hypothetical protein	A0A192Y6Q5	Salmonella_phage	6.3e-21	76.1
WP_130949579.1\|1207199_1208063_-	hypothetical protein	M9NYX6	Enterobacteria_phage	7.5e-95	62.5
WP_016831735.1\|1208169_1208289_-	hypothetical protein	NA	NA	NA	NA
WP_136085610.1\|1208394_1208493_-	YoaK family small membrane protein	NA	NA	NA	NA
WP_004190707.1\|1208510_1208906_-	helix-turn-helix transcriptional regulator	K7PM35	Enterobacteria_phage	3.1e-48	74.0
WP_029503646.1\|1209010_1209244_+	Rha family transcriptional regulator	A0A0M4QX15	Salmonella_phage	2.1e-20	61.6
WP_023287506.1\|1209246_1209783_+	bacteriophage regulatory protein CII	K7PJT7	Enterobacteria_phage	2.1e-63	70.4
WP_023286277.1\|1209870_1210059_+	hypothetical protein	NA	NA	NA	NA
WP_032417026.1\|1210983_1211733_+	ATP-binding protein	H6WRX8	Salmonella_phage	1.3e-119	83.1
WP_117038221.1\|1211740_1212109_+	DUF977 family protein	H6WRX9	Salmonella_phage	1.8e-10	41.8
WP_060876940.1\|1212108_1212366_+	hypothetical protein	NA	NA	NA	NA
WP_143444308.1\|1212362_1214345_+	DNA cytosine methyltransferase	H9C171	Pectobacterium_phage	9.5e-202	53.2
WP_064185108.1\|1214379_1214928_+	hypothetical protein	NA	NA	NA	NA
WP_134726016.1\|1215266_1215746_+	hypothetical protein	NA	NA	NA	NA
WP_023304767.1\|1216420_1216654_+	hypothetical protein	A0A0M4R5D9	Salmonella_phage	9.9e-18	57.1
WP_023322448.1\|1216689_1217286_+	DUF1367 family protein	K7PKS6	Enterobacteria_phage	8.5e-90	80.1
WP_032422218.1\|1217285_1217492_+	hypothetical protein	H6WRY8	Salmonella_phage	1.1e-23	72.7
WP_004892208.1\|1217494_1217791_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	1.2e-36	72.9
WP_023282412.1\|1217787_1218144_+	RusA family crossover junction endodeoxyribonuclease	K7P6W0	Enterobacteria_phage	1.5e-41	64.1
WP_023282413.1\|1218259_1219081_+	antitermination protein	K7PKS8	Enterobacteria_phage	4.0e-98	67.1
WP_025983157.1\|1219767_1220163_+	membrane protein	G8C7V8	Escherichia_phage	1.5e-45	73.1
WP_008806056.1\|1220149_1220431_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.3e-32	73.1
WP_032417032.1\|1220430_1221060_+	glycoside hydrolase family 19 protein	G9L6E8	Escherichia_phage	3.1e-90	77.5
WP_032417033.1\|1221062_1221338_+	hypothetical protein	G8C7W1	Escherichia_phage	2.2e-08	40.0
WP_050485568.1\|1221288_1221480_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	1.8e-25	94.9
WP_130946567.1\|1221613_1222225_-	hypothetical protein	NA	NA	NA	NA
WP_101827254.1\|1223485_1224502_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7
WP_050512794.1\|1224916_1225285_+	zinc ribbon domain-containing protein	I6PDJ9	Cronobacter_phage	6.6e-16	43.7
WP_032445346.1\|1225357_1228015_+\|tail	tail protein	A0A2D1GPC9	Escherichia_phage	3.6e-87	34.8
WP_032417047.1\|1228014_1228479_+	hypothetical protein	A0A286S298	Klebsiella_phage	6.7e-58	67.8
WP_143444309.1\|1228720_1230049_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_032417048.1\|1230097_1230580_+	DUF1833 family protein	A0A286S2B1	Klebsiella_phage	2.9e-80	93.8
WP_016946669.1\|1230589_1230970_+	hypothetical protein	A0A286S2A6	Klebsiella_phage	3.1e-69	95.2
WP_032417049.1\|1230966_1234035_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	96.3
WP_032417050.1\|1236717_1237812_+	hypothetical protein	A0A248XD67	Klebsiella_phage	2.0e-177	86.8

DBSCAN-SWA_2

1459172 : 1498620

Pseudomonas_phage(45.95%)

integrase,terminase,transposase,plate,head,tail

attL 1481664:1481679|attR 1502412:1502427

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064375583.1\|1459172_1459802_-	ParB-like nuclease domain-containing protein	A0A0F7L444	uncultured_marine_virus	8.0e-54	51.3
WP_143444319.1\|1460529_1461624_-	hypothetical protein	A0A248XD67	Klebsiella_phage	6.4e-168	82.7
WP_143444320.1\|1461628_1464421_-	hypothetical protein	A0A248XD04	Klebsiella_phage	0.0e+00	84.7
WP_020804748.1\|1464407_1465031_-\|tail	tail fiber assembly protein	A0A0F7LDQ5	Escherichia_phage	3.1e-34	43.2
WP_020804710.1\|1465030_1465774_-\|tail	tail fiber protein	A0A0U2DA62	Escherichia_phage	8.0e-21	57.1
WP_020804756.1\|1465785_1466442_-	DUF2313 domain-containing protein	F6MIL7	Haemophilus_phage	6.2e-33	39.8
WP_117252891.1\|1466438_1467500_-\|plate	baseplate J/gp47 family protein	A0A0M3LQN4	Mannheimia_phage	9.6e-76	47.8
WP_060591309.1\|1467499_1467856_-	hypothetical protein	A0A0M3LQK5	Mannheimia_phage	6.8e-26	55.1
WP_080876734.1\|1467921_1468503_-\|plate	phage baseplate assembly protein	A0A0M3LPA3	Mannheimia_phage	5.9e-35	52.4
WP_064360179.1\|1468486_1469725_-	hypothetical protein	A0A2H4J9E6	uncultured_Caudovirales_phage	4.9e-71	35.4
WP_080876736.1\|1469708_1471022_-	multidrug DMT transporter permease	A0A0M3LQ21	Mannheimia_phage	6.2e-24	21.8
WP_117252890.1\|1471021_1473199_-\|tail	phage tail tape measure protein	B5TAA4	Burkholderia_phage	1.6e-32	27.0
WP_117005993.1\|1473318_1473714_-	hypothetical protein	NA	NA	NA	NA
WP_064360183.1\|1473713_1474088_-	hypothetical protein	A0A0M3LRV6	Mannheimia_phage	9.3e-26	50.8
WP_117252889.1\|1474099_1475518_-\|tail	phage tail protein	B7SDP8	Haemophilus_phage	7.2e-103	50.1
WP_117252888.1\|1475517_1475715_-	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_117252887.1\|1475695_1476355_-	DUF1834 family protein	NA	NA	NA	NA
WP_117252886.1\|1476351_1476780_-	DUF1320 family protein	A0A219VH93	Ochrobactrum_phage	1.6e-13	38.5
WP_117252885.1\|1476789_1477188_-	hypothetical protein	NA	NA	NA	NA
WP_117252884.1\|1477188_1478097_-\|head	head protein	A0A2H4J778	uncultured_Caudovirales_phage	5.5e-96	57.3
WP_117252883.1\|1478108_1478504_-	hypothetical protein	J9RWG0	Pseudomonas_phage	2.4e-24	51.5
WP_117252882.1\|1478496_1479582_-	hypothetical protein	A0A0M5N0Q6	Ralstonia_phage	7.5e-52	41.7
WP_117005991.1\|1479816_1480362_-	phage virion morphogenesis protein	A0A2D1GNX5	Pseudomonas_phage	1.8e-09	31.5
WP_117252881.1\|1480351_1481623_-\|head	phage head morphogenesis protein	A0A0A7DJT5	Pseudomonas_phage	3.7e-50	36.0
WP_080876745.1\|1481615_1483184_-	DUF935 domain-containing protein	A0A125RNC0	Pseudomonas_phage	1.8e-123	45.9
1481664:1481679	attL	NA	NA	NA	NA
WP_117252880.1\|1483183_1484887_-\|terminase	phage terminase large subunit	A0A0A1IW02	Pseudomonas_phage	1.5e-195	64.3
WP_117252879.1\|1484891_1485251_-	hypothetical protein	NA	NA	NA	NA
WP_117252878.1\|1485254_1485584_-	ammonia monooxygenase	G8GWD9	Rhodobacter_phage	5.8e-32	61.1
WP_080876747.1\|1485587_1485797_-	hypothetical protein	NA	NA	NA	NA
WP_080876748.1\|1485789_1486290_-	DUF1804 family protein	I6PBD1	Pseudomonas_phage	5.2e-48	55.4
WP_088911576.1\|1486291_1486606_-	hypothetical protein	NA	NA	NA	NA
WP_064360196.1\|1486602_1486848_-	hypothetical protein	NA	NA	NA	NA
WP_071199240.1\|1486844_1487480_-	hypothetical protein	NA	NA	NA	NA
WP_047935294.1\|1487469_1487718_-	DUF2644 domain-containing protein	NA	NA	NA	NA
WP_080876750.1\|1487699_1488353_-	glycoside hydrolase family 19 protein	A0A2D1GNI0	Pseudomonas_phage	1.3e-62	58.7
WP_088911574.1\|1488434_1488926_-	hypothetical protein	NA	NA	NA	NA
WP_117005987.1\|1488935_1489370_-	hypothetical protein	A0A2D1GNW5	Pseudomonas_phage	3.4e-27	46.2
WP_064360201.1\|1489314_1489791_-	regulatory protein GemA	A0A2D1GNN4	Pseudomonas_phage	9.6e-44	64.4
WP_110540648.1\|1489850_1490066_-	hypothetical protein	A0A2D1GNS9	Pseudomonas_phage	1.1e-20	66.2
WP_117252877.1\|1490046_1490769_-	hypothetical protein	NA	NA	NA	NA
WP_117252876.1\|1490765_1491044_-	hypothetical protein	NA	NA	NA	NA
WP_117252875.1\|1491036_1491303_-	DUF977 family protein	NA	NA	NA	NA
WP_117252874.1\|1491439_1491979_-	HD family hydrolase	A0A2D1GNL9	Pseudomonas_phage	7.5e-61	70.4
WP_049593289.1\|1491975_1492200_-	hypothetical protein	A0A2D1GNI2	Pseudomonas_phage	2.6e-15	52.8
WP_117252873.1\|1492212_1492731_-	hypothetical protein	A0A2D1GNV6	Pseudomonas_phage	5.2e-35	45.5
WP_117100345.1\|1492731_1492941_-	hypothetical protein	NA	NA	NA	NA
WP_143444321.1\|1492972_1493161_-	hypothetical protein	A0A2D1GNV5	Pseudomonas_phage	4.1e-06	54.2
WP_071199250.1\|1493162_1493801_-	DUF3164 family protein	J9SHK0	Pseudomonas_phage	8.1e-62	59.1
WP_102811806.1\|1493793_1493985_-	hypothetical protein	NA	NA	NA	NA
WP_020804713.1\|1493986_1494220_-	hypothetical protein	NA	NA	NA	NA
WP_127702660.1\|1494235_1494454_-	hypothetical protein	NA	NA	NA	NA
WP_088911564.1\|1494462_1495356_-	AAA family ATPase	A0A2D1GNS0	Pseudomonas_phage	1.9e-101	60.8
WP_117252872.1\|1495368_1497429_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2D1GNK9	Pseudomonas_phage	4.5e-170	48.7
WP_023158148.1\|1497433_1497697_-	transcriptional regulator	F6MII4	Haemophilus_phage	2.1e-24	67.9
WP_117252895.1\|1497894_1498620_+	helix-turn-helix transcriptional regulator	A5X9F5	Aeromonas_virus	2.2e-23	37.1
1502412:1502427	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1751621 : 1759059

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009653787.1\|1751621_1752908_-	DUF3596 domain-containing protein	A0A0U2JGI6	Escherichia_phage	5.7e-123	54.6
WP_004111685.1\|1752907_1753123_-	DUF1233 family excisionase	NA	NA	NA	NA
WP_049111946.1\|1753210_1753555_-	hypothetical protein	NA	NA	NA	NA
WP_070596239.1\|1753551_1753908_-	hypothetical protein	Q5G8U7	Enterobacteria_phage	2.9e-53	80.4
WP_009653810.1\|1753904_1754210_-	hypothetical protein	NA	NA	NA	NA
WP_141749737.1\|1754224_1754458_-	hypothetical protein	NA	NA	NA	NA
WP_070596244.1\|1754523_1754817_-	host cell division inhibitory peptide Kil	NA	NA	NA	NA
WP_064377515.1\|1755303_1755708_-	helix-turn-helix domain-containing protein	B1B6L9	Salmonella_phage	1.2e-13	54.9
WP_064377477.1\|1755787_1756015_+	transcriptional regulator	K7PHK4	Enterobacteria_phage	1.8e-08	42.6
WP_064404685.1\|1755998_1756424_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_049095182.1\|1756437_1756692_+	hypothetical protein	NA	NA	NA	NA
WP_064404683.1\|1756688_1757765_+	hypothetical protein	U5P0A0	Shigella_phage	2.1e-22	43.7
WP_070596246.1\|1757778_1758072_+	hypothetical protein	NA	NA	NA	NA
WP_070596248.1\|1758068_1758281_+	hypothetical protein	NA	NA	NA	NA
WP_070596250.1\|1758273_1759059_+	hypothetical protein	A4JX52	Burkholderia_virus	1.1e-60	49.8

DBSCAN-SWA_4

1762404 : 1792422

Klebsiella_phage(50.0%)

protease,terminase,portal,head,tail,capsid,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014228555.1\|1762404_1762638_+	DinI family protein	H6WRY5	Salmonella_phage	1.3e-25	68.8
WP_004111729.1\|1762764_1762947_+	hypothetical protein	NA	NA	NA	NA
WP_064375010.1\|1763113_1763707_+	hypothetical protein	A0A0M4RU10	Salmonella_phage	2.4e-44	69.0
WP_072351724.1\|1763703_1764363_+	phage N-6-adenine-methyltransferase	Q8HA94	Salmonella_phage	3.3e-103	80.8
WP_064375011.1\|1764359_1764938_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	4.4e-51	57.8
WP_143444531.1\|1765577_1765877_+\|holin	holin	A0A286N2Q5	Klebsiella_phage	2.5e-45	97.9
WP_143444330.1\|1765873_1766416_+	hypothetical protein	A0A286N2Q6	Klebsiella_phage	5.8e-77	77.5
WP_087867214.1\|1766412_1766760_+	hypothetical protein	A0A286N2Q7	Klebsiella_phage	4.4e-38	76.5
WP_087867213.1\|1766756_1767026_+	hypothetical protein	NA	NA	NA	NA
WP_087867212.1\|1766976_1767159_+	hypothetical protein	A0A286SGR9	Klebsiella_phage	3.9e-14	63.8
WP_142928200.1\|1767193_1767667_+	hypothetical protein	NA	NA	NA	NA
WP_143444331.1\|1767839_1768190_+	HNH endonuclease	K7PHK9	Enterobacteria_phage	1.0e-50	78.4
WP_047720924.1\|1768348_1768846_+\|terminase	phage terminase small subunit P27 family	K7PHI2	Enterobacteria_phage	2.5e-63	72.0
WP_130989162.1\|1768849_1770601_+\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	1.3e-258	71.8
WP_071957418.1\|1770611_1770797_+	hypothetical protein	S5FXQ9	Shigella_phage	4.0e-14	59.3
WP_071199611.1\|1770796_1772026_+\|portal	phage portal protein	U5P411	Shigella_phage	1.6e-204	82.4
WP_130989208.1\|1772012_1772666_+\|head,protease	HK97 family phage prohead protease	Q8W628	Enterobacteria_phage	4.6e-105	86.4
WP_065953941.1\|1772680_1773889_+\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	4.0e-195	85.7
WP_065953940.1\|1773927_1774131_+	hypothetical protein	S5FNU1	Shigella_phage	3.6e-08	50.0
WP_065953939.1\|1774127_1774448_+\|head,tail	phage gp6-like head-tail connector protein	K7PKT4	Enterobacteria_phage	1.7e-15	38.6
WP_065953938.1\|1774517_1774730_+	hypothetical protein	A0A286S2A5	Klebsiella_phage	1.3e-13	68.6
WP_065953937.1\|1774731_1775064_+\|head	phage head closure protein	A0A286S2A2	Klebsiella_phage	1.0e-44	81.8
WP_064398063.1\|1775056_1775596_+	HK97 gp10 family phage protein	A0A286S249	Klebsiella_phage	1.8e-86	91.1
WP_143444332.1\|1775592_1775958_+	DUF3168 domain-containing protein	A0A286S1R1	Klebsiella_phage	1.7e-56	86.0
WP_142472161.1\|1776016_1776508_+\|tail	phage tail protein	A0A286S1Q8	Klebsiella_phage	4.6e-81	91.4
WP_064355145.1\|1776550_1776934_+\|tail	phage tail protein	A0A286S1N4	Klebsiella_phage	2.7e-52	83.8
WP_142468673.1\|1776936_1777200_+\|tail	phage tail protein	A0A286S1P2	Klebsiella_phage	9.7e-38	83.9
WP_025108047.1\|1777263_1777656_+	hypothetical protein	A0A286S1N7	Klebsiella_phage	4.7e-20	41.4
WP_143444333.1\|1777717_1780147_+\|tail	phage tail tape measure protein	A0A286S1S3	Klebsiella_phage	0.0e+00	80.0
WP_143444334.1\|1780146_1780626_+	hypothetical protein	A0A286S298	Klebsiella_phage	4.0e-90	94.3
WP_143444335.1\|1780612_1781095_+	DUF1833 family protein	A0A286S2B1	Klebsiella_phage	5.5e-79	90.6
WP_064375423.1\|1781104_1781485_+	hypothetical protein	A0A286S2A6	Klebsiella_phage	2.6e-68	92.9
WP_143444336.1\|1781481_1784550_+	kinase	A0A286S259	Klebsiella_phage	0.0e+00	92.5
WP_143444337.1\|1787233_1788328_+	hypothetical protein	A0A248XD67	Klebsiella_phage	3.8e-176	86.0
WP_072351784.1\|1788648_1788888_+	hypothetical protein	K7P7N3	Enterobacteria_phage	1.1e-19	58.2
WP_064375420.1\|1788887_1789214_+	hypothetical protein	K7PGV5	Enterobacterial_phage	4.2e-22	50.0
WP_072351781.1\|1789560_1789977_+	hypothetical protein	K7P834	Enterobacteria_phage	3.0e-25	46.1
WP_064375419.1\|1790432_1791635_+	serine-type D-Ala-D-Ala carboxypeptidase	B6DZZ7	Stx2-converting_phage	3.6e-95	46.7
WP_004849345.1\|1791663_1792422_-	DNA-binding transcriptional repressor DeoR	A0A077SK06	Escherichia_phage	2.0e-11	27.2

DBSCAN-SWA_5

2402187 : 2530517

112

Enterobacteria_phage(20.69%)

protease,transposase,plate,tail,tRNA,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049080383.1\|2402187_2403531_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_014229072.1\|2403527_2404193_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_064375458.1\|2404189_2405878_+	OmpA family protein	NA	NA	NA	NA
WP_014229074.1\|2406022_2406514_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_101827254.1\|2406840_2407857_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7
WP_025107999.1\|2409235_2410690_-	MFS transporter	NA	NA	NA	NA
WP_014229093.1\|2411647_2412607_-	DUF523 and DUF1722 domain-containing protein	NA	NA	NA	NA
WP_025107997.1\|2412621_2413155_-	DUF3833 domain-containing protein	NA	NA	NA	NA
WP_014838292.1\|2413151_2414375_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_047723943.1\|2414371_2415094_-	DUF1365 domain-containing protein	NA	NA	NA	NA
WP_064375602.1\|2416350_2417070_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_064375601.1\|2417066_2417501_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_064375600.1\|2417799_2418879_-	porin	Q1MVN1	Enterobacteria_phage	3.3e-92	46.1
WP_064375599.1\|2418984_2420400_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_143444353.1\|2420459_2420702_-	hypothetical protein	NA	NA	NA	NA
WP_143444354.1\|2420758_2421853_-	PTS transporter subunit EIIB	NA	NA	NA	NA
WP_064375597.1\|2422098_2423010_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_032693666.1\|2423088_2423814_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	3.5e-45	46.4
WP_072351814.1\|2423915_2424260_-	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_064375595.1\|2425687_2426824_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014229104.1\|2426995_2427880_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_009653016.1\|2427993_2428878_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_048263680.1\|2429036_2430017_+	nitronate monooxygenase	NA	NA	NA	NA
WP_048263679.1\|2430061_2430892_-	oxidoreductase	NA	NA	NA	NA
WP_064375594.1\|2431086_2432112_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_071532263.1\|2432950_2433139_+	cold-shock protein	NA	NA	NA	NA
WP_014838304.1\|2433508_2434138_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_032720811.1\|2434263_2434845_+	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_014229112.1\|2435041_2435605_+	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_004850294.1\|2435659_2435974_-	PTS cellobiose transporter subunit IIB	NA	NA	NA	NA
WP_004850297.1\|2436151_2436343_-	hypothetical protein	NA	NA	NA	NA
WP_014229113.1\|2436499_2436694_-	hypothetical protein	NA	NA	NA	NA
WP_004850301.1\|2436981_2437404_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.6e-32	51.2
WP_025107982.1\|2437403_2438669_+	translesion error-prone DNA polymerase V subunit UmuC	I6RSM4	Salmonella_phage	3.5e-157	66.4
WP_025107981.1\|2438741_2439809_-	oxidoreductase	NA	NA	NA	NA
WP_025107980.1\|2439825_2440569_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.1e-14	27.6
WP_064375591.1\|2441185_2441806_+	response regulator transcription factor	NA	NA	NA	NA
WP_004850311.1\|2442148_2443132_+	zinc transporter ZntB	NA	NA	NA	NA
WP_014229118.1\|2443615_2444989_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.8e-50	31.8
WP_025107977.1\|2445033_2445969_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.4e-139	93.4
WP_064375607.1\|2446781_2447720_+\|protease	omptin family outer membrane protease	NA	NA	NA	NA
WP_014229121.1\|2448118_2448409_-	hypothetical protein	C6ZCX3	Enterobacteria_phage	9.7e-31	66.0
WP_004101601.1\|2448597_2449032_-	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	7.2e-30	51.4
WP_064358488.1\|2449114_2449327_-	KTSC domain-containing protein	NA	NA	NA	NA
WP_004850328.1\|2449480_2450587_-	porin OmpC	Q1MVN1	Enterobacteria_phage	3.8e-107	57.7
WP_102803582.1\|2450519_2450759_-	hypothetical protein	NA	NA	NA	NA
WP_025107972.1\|2450944_2454472_-	pyruvate:ferredoxin (flavodoxin) oxidoreductase	NA	NA	NA	NA
WP_009653037.1\|2455116_2455653_+	helix-turn-helix transcriptional regulator	K7PKK1	Enterobacteria_phage	5.2e-30	49.7
WP_064375589.1\|2456116_2456479_+	hypothetical protein	C6ZR44	Salmonella_phage	3.2e-31	57.5
WP_025107970.1\|2456555_2456948_+	membrane protein	K7PHB9	Enterobacterial_phage	4.5e-39	66.9
WP_032749344.1\|2456937_2457210_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	2.2e-16	55.4
WP_004850338.1\|2457217_2457760_+	glycoside hydrolase family 108 protein	A0A0U2I1S0	Escherichia_phage	5.2e-70	66.7
WP_004850340.1\|2457815_2458235_+	hypothetical protein	Q6UAS0	Klebsiella_phage	9.4e-35	51.5
WP_014229127.1\|2458354_2459017_+\|tail	phage tail protein	I6PBN6	Cronobacter_phage	7.0e-77	65.0
WP_004850345.1\|2459089_2459401_+	hypothetical protein	I6PDG2	Cronobacter_phage	1.5e-32	62.1
WP_048263674.1\|2459463_2459709_+	hypothetical protein	A0A2H4J4F7	uncultured_Caudovirales_phage	2.3e-09	40.0
WP_064375588.1\|2459793_2460903_+\|tail	phage tail tape measure protein	I6PCW3	Cronobacter_phage	5.9e-52	48.5
WP_025107966.1\|2460925_2461273_+\|tail	phage tail protein	I6PBN7	Cronobacter_phage	1.8e-36	60.0
WP_025107965.1\|2461269_2462022_+\|tail	phage minor tail protein L	K7PKU0	Enterobacteria_phage	5.7e-115	76.3
WP_004850357.1\|2462924_2463539_+\|tail	tail assembly protein	K7PM97	Enterobacterial_phage	1.2e-67	69.6
WP_004101621.1\|2470520_2470793_+	DUF333 domain-containing protein	NA	NA	NA	NA
WP_014229134.1\|2470789_2471230_-	heat shock protein HslJ	NA	NA	NA	NA
WP_064375761.1\|2471355_2472345_-	2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	1.6e-69	45.4
WP_004850371.1\|2472494_2472992_-	DedA family protein	NA	NA	NA	NA
WP_064375762.1\|2473187_2475827_+	YdbH family protein	NA	NA	NA	NA
WP_004121063.1\|2475826_2476012_+	YnbE family lipoprotein	NA	NA	NA	NA
WP_014838317.1\|2476019_2476343_+	YdbL family protein	NA	NA	NA	NA
WP_025107961.1\|2476343_2477252_-	transcriptional regulator FeaR	NA	NA	NA	NA
WP_064375763.1\|2477487_2478987_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_032720803.1\|2479143_2479875_-	hypothetical protein	NA	NA	NA	NA
WP_014229141.1\|2479879_2480710_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004850399.1\|2480733_2481606_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_049079908.1\|2481632_2483153_-	amino acid ABC transporter permease/ATP-binding protein	W8CYL7	Bacillus_phage	1.9e-08	27.1
WP_009653045.1\|2483640_2484558_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004139129.1\|2486009_2486444_+	RidA family protein	NA	NA	NA	NA
WP_014229145.1\|2486440_2487115_+	DUF1028 domain-containing protein	NA	NA	NA	NA
WP_064375765.1\|2487107_2488277_+	acetylornithine deacetylase	NA	NA	NA	NA
WP_049082239.1\|2488300_2489116_+	phytanoyl-CoA dioxygenase	NA	NA	NA	NA
WP_143444355.1\|2489915_2490242_+	hypothetical protein	NA	NA	NA	NA
WP_143444356.1\|2490286_2490712_+	hypothetical protein	NA	NA	NA	NA
WP_064375767.1\|2491063_2491600_-	dihydrofolate reductase	NA	NA	NA	NA
WP_064375768.1\|2491672_2492791_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_064375769.1\|2494119_2494992_-	HlyD family secretion protein	NA	NA	NA	NA
WP_014229155.1\|2494988_2495204_-	DUF1656 domain-containing protein	NA	NA	NA	NA
WP_064375770.1\|2495193_2497233_-	FUSC family protein	NA	NA	NA	NA
WP_009653008.1\|2497310_2498105_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004850429.1\|2498179_2498554_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_064375771.1\|2498891_2500067_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_070596112.1\|2503294_2504623_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_004121015.1\|2504745_2505225_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_064375858.1\|2505473_2506094_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_064358476.1\|2506377_2507067_+	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	5.7e-13	29.1
WP_025107943.1\|2507137_2507884_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.5e-06	30.8
WP_143444532.1\|2508439_2508988_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_064375857.1\|2509235_2510732_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_064375856.1\|2510770_2511538_+	acetyltransferase	NA	NA	NA	NA
WP_049082479.1\|2513421_2514432_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_014229170.1\|2514510_2515491_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_049082482.1\|2515987_2516827_+	hypothetical protein	NA	NA	NA	NA
WP_064375888.1\|2516944_2518024_-	SMEK domain-containing protein	NA	NA	NA	NA
WP_101827254.1\|2518299_2519316_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7
WP_072351869.1\|2519472_2519925_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_049082507.1\|2520212_2521124_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_049082508.1\|2521220_2522210_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_049082513.1\|2522324_2523152_-	streptomycin kinase	NA	NA	NA	NA
WP_048263566.1\|2523379_2523985_-	glutathione transferase GstA	NA	NA	NA	NA
WP_049070134.1\|2524105_2524981_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_071846104.1\|2525028_2525256_-	DUF1272 domain-containing protein	NA	NA	NA	NA
WP_143444357.1\|2525564_2526428_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_048263569.1\|2526598_2527024_+	VOC family protein	NA	NA	NA	NA
WP_046877265.1\|2527218_2527872_-	LysE family translocator	NA	NA	NA	NA
WP_000227969.1\|2529440_2530517_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

3070256 : 3137822

Klebsiella_phage(36.59%)

integrase,terminase,transposase,lysis,head,tail

attL 3085475:3085491|attR 3114958:3114974

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101827254.1\|3070256_3071273_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	1.7e-186	99.7
WP_049082727.1\|3071761_3072667_-	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
WP_049082726.1\|3072898_3073639_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_032694459.1\|3073746_3074670_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004851318.1\|3074750_3076364_+	two-component system sensor histidine kinase DcuS	NA	NA	NA	NA
WP_025105800.1\|3076360_3077080_+	two-component system response regulator DcuR	NA	NA	NA	NA
WP_014838638.1\|3077060_3078011_-	FAD:protein FMN transferase	NA	NA	NA	NA
WP_064374899.1\|3078078_3080856_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	4.7e-66	30.8
WP_004851326.1\|3081483_3082989_+	anion permease	NA	NA	NA	NA
WP_064374898.1\|3083040_3084696_+	fumarate hydratase	NA	NA	NA	NA
WP_046876593.1\|3084776_3085160_-	4-carboxymuconolactone decarboxylase	NA	NA	NA	NA
WP_064374897.1\|3085149_3085917_-	3-oxoadipate enol-lactonase	NA	NA	NA	NA
3085475:3085491	attL	NA	NA	NA	NA
WP_064374896.1\|3085906_3087259_-	3-carboxy-cis,cis-muconate cycloisomerase	NA	NA	NA	NA
WP_004851337.1\|3087268_3088471_-	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
WP_046876591.1\|3088481_3089138_-	CoA transferase subunit B	NA	NA	NA	NA
WP_049079304.1\|3089148_3089835_-	3-oxoacid CoA-transferase subunit A	NA	NA	NA	NA
WP_004851343.1\|3090002_3090809_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004851345.1\|3090805_3091369_-	DNA endonuclease SmrA	NA	NA	NA	NA
WP_014229560.1\|3091451_3092360_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_048262175.1\|3092526_3093837_+	M20 family metallo-hydrolase	NA	NA	NA	NA
WP_048262176.1\|3093836_3095282_+	amidohydrolase	NA	NA	NA	NA
WP_004146386.1\|3096640_3097741_+\|integrase	site-specific integrase	A0A1W6JP34	Morganella_phage	2.9e-115	56.8
WP_065242224.1\|3097951_3098233_-	hypothetical protein	NA	NA	NA	NA
WP_143444384.1\|3098975_3099788_+	hypothetical protein	NA	NA	NA	NA
WP_143444385.1\|3099915_3101013_-	hypothetical protein	A0A248XD67	Klebsiella_phage	7.1e-175	85.7
WP_143444386.1\|3104472_3105246_-	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	4.1e-68	53.3
WP_064364844.1\|3106440_3106794_-	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	3.9e-50	79.5
WP_143444387.1\|3106795_3107449_-	hypothetical protein	A0A0M5M1K7	Salmonella_phage	5.7e-71	57.9
WP_143444388.1\|3107671_3108037_+	hypothetical protein	NA	NA	NA	NA
WP_143444389.1\|3108048_3108402_-	hypothetical protein	A0A0M4RTY3	Salmonella_phage	5.0e-29	82.1
WP_143444390.1\|3108404_3109469_-	hypothetical protein	A0A0M4QX01	Salmonella_phage	4.8e-136	68.6
WP_143444391.1\|3109471_3109774_-	hypothetical protein	A0A0M4R5B7	Salmonella_phage	3.1e-24	52.0
WP_143444392.1\|3109774_3110350_-	hypothetical protein	A0A0M3ULD5	Salmonella_phage	6.6e-63	69.6
WP_004152565.1\|3112335_3112488_-	hypothetical protein	A0A2H4J1A2	uncultured_Caudovirales_phage	7.6e-19	88.0
WP_143444393.1\|3112523_3112949_-	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	6.8e-41	64.2
WP_004199809.1\|3112952_3113393_-	DUF3277 family protein	A0A0M5M1K6	Salmonella_phage	3.3e-62	80.1
WP_143444394.1\|3113403_3114549_-	DUF3383 family protein	A0A2H4J8G4	uncultured_Caudovirales_phage	3.8e-155	73.2
WP_143444538.1\|3114552_3114993_-	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	2.3e-39	52.4
3114958:3114974	attR	NA	NA	NA	NA
WP_143444395.1\|3115087_3115474_-\|head,tail	head-tail adaptor	A0A2H4J1A4	uncultured_Caudovirales_phage	1.1e-45	74.2
WP_143444396.1\|3115473_3115971_-	hypothetical protein	NA	NA	NA	NA
WP_143444397.1\|3115967_3116378_-	DUF4054 domain-containing protein	A0A2H4J1A6	uncultured_Caudovirales_phage	6.8e-30	53.3
WP_064353321.1\|3116349_3116703_-	hypothetical protein	NA	NA	NA	NA
WP_064353320.1\|3116750_3117698_-	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	5.1e-97	55.3
WP_143444398.1\|3117708_3118212_-	hypothetical protein	A0A0M4QWZ6	Salmonella_phage	4.0e-32	47.9
WP_143444399.1\|3118223_3119507_-	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	1.5e-78	41.4
WP_142462483.1\|3119516_3119711_-	hypothetical protein	NA	NA	NA	NA
WP_077253535.1\|3119936_3121283_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_004143398.1\|3121331_3121727_+	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_104460111.1\|3121968_3122589_-\|terminase	terminase small subunit	I3PUX8	Vibrio_phage	2.2e-40	45.8
WP_143444400.1\|3122962_3123193_-	hypothetical protein	NA	NA	NA	NA
WP_143444401.1\|3123233_3123701_-\|lysis	lysis protein	Q76H63	Enterobacteria_phage	2.2e-56	74.2
WP_143444402.1\|3123697_3124237_-	glycoside hydrolase family protein	H6WRZ4	Salmonella_phage	1.1e-88	84.8
WP_004151282.1\|3124239_3124488_-	hypothetical protein	NA	NA	NA	NA
WP_143444403.1\|3125222_3126158_+	hypothetical protein	NA	NA	NA	NA
WP_143444539.1\|3126296_3126752_+	hypothetical protein	NA	NA	NA	NA
WP_143444404.1\|3126785_3127133_-	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	1.5e-54	86.4
WP_143444405.1\|3127214_3127691_-	hypothetical protein	A0A286N2Q1	Klebsiella_phage	4.0e-90	99.4
WP_143444406.1\|3127687_3128650_-	DNA primase	A0A286N2Q0	Klebsiella_phage	3.1e-182	99.1
WP_143444540.1\|3128651_3130298_-	DEAD/DEAH box helicase family protein	A0A286N2P9	Klebsiella_phage	8.5e-273	80.8
WP_004152163.1\|3130607_3130901_-	hypothetical protein	A0A286S2B5	Klebsiella_phage	2.8e-38	97.6
WP_004152162.1\|3130875_3131097_-	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	3.0e-32	100.0
WP_004152161.1\|3131194_3131863_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.4e-125	99.5
WP_004152160.1\|3132033_3132348_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.0e-49	100.0
WP_143444407.1\|3132340_3132529_+	hypothetical protein	A0A286S1P8	Klebsiella_phage	2.3e-25	98.4
WP_004152158.1\|3132698_3133064_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	6.9e-58	99.2
WP_143444408.1\|3133056_3133311_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	1.8e-36	89.3
WP_143444409.1\|3133282_3133501_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	1.1e-26	87.0
WP_143444410.1\|3133497_3133929_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	1.4e-70	92.9
WP_064388511.1\|3133972_3134491_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	6.9e-88	90.7
WP_143444411.1\|3134496_3135213_+	DNA-binding protein	A0A286S260	Klebsiella_phage	9.8e-125	97.0
WP_047719108.1\|3135209_3135773_+	hypothetical protein	A0A088C4R7	Shewanella_sp._phage	1.1e-25	37.2
WP_143444412.1\|3135916_3137245_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_023313034.1\|3137561_3137822_+	hypothetical protein	A0A1L5C290	Pseudoalteromonas_phage	1.5e-11	43.7

DBSCAN-SWA_7

3857362 : 3865757

Bacillus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143444446.1\|3857362_3858898_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	2.8e-28	27.6
WP_014230101.1\|3858894_3859617_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	2.4e-30	32.7
WP_025107782.1\|3859935_3861297_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.6e-200	92.0
WP_009654032.1\|3861541_3862435_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	8.8e-14	28.9
WP_014230103.1\|3862435_3862906_-	hypothetical protein	NA	NA	NA	NA
WP_032693715.1\|3862892_3863693_-	CadC family transcriptional regulator	NA	NA	NA	NA
WP_014230105.1\|3864109_3864883_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.8e-27	37.7
WP_032719918.1\|3864893_3865757_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-11	29.0

DBSCAN-SWA_8

4809676 : 4857106

Stx2-converting_phage(25.0%)

integrase,transposase

attL 4829456:4829470|attR 4858720:4858734

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_064362539.1\|4809676_4811215_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.7e-271	90.8
WP_000227969.1\|4811541_4812618_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_064362542.1\|4812937_4814008_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_141749718.1\|4815173_4816291_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.0e-52	44.1
WP_048268169.1\|4816669_4817293_+	hypothetical protein	NA	NA	NA	NA
WP_048268170.1\|4817443_4818454_-	formamidase	NA	NA	NA	NA
WP_048268171.1\|4818486_4819176_-	urea ABC transporter ATP-binding subunit UrtE	A0A2H4PQG7	Staphylococcus_phage	8.0e-15	25.2
WP_048268172.1\|4819186_4819936_-	urea ABC transporter ATP-binding protein UrtD	W6JKT0	Anomala_cuprea_entomopoxvirus	4.2e-17	28.1
WP_048268174.1\|4821069_4821996_-	urea ABC transporter permease subunit UrtB	NA	NA	NA	NA
WP_101857421.1\|4822049_4823240_-	urea ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_048268177.1\|4826895_4827801_+	response regulator	W8CYM9	Bacillus_phage	6.4e-12	32.5
4829456:4829470	attL	NA	NA	NA	NA
WP_004189163.1\|4830063_4830504_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	2.6e-19	60.3
WP_004189161.1\|4830500_4830851_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	5.2e-39	63.8
WP_004902302.1\|4830881_4832474_+\|transposase	IS66-like element ISKox1 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.2e-176	61.8
WP_048268181.1\|4833715_4836964_-	DEAD/DEAH box helicase	A0A1B1ISM1	uncultured_Mediterranean_phage	1.9e-26	25.1
WP_048268182.1\|4836963_4838646_-	hypothetical protein	NA	NA	NA	NA
WP_048266230.1\|4838642_4839383_-	OmpA family protein	NA	NA	NA	NA
WP_048268183.1\|4839396_4841586_-	anti-phage defense ZorAB system ZorA	NA	NA	NA	NA
WP_064362547.1\|4841914_4844275_+	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	1.5e-28	23.9
WP_064362549.1\|4844274_4845681_+	hypothetical protein	NA	NA	NA	NA
WP_048268186.1\|4845677_4848926_+	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_048268187.1\|4848955_4850938_+	AAA domain-containing protein	K4I1H4	Acidithiobacillus_phage	3.9e-30	39.8
WP_048268189.1\|4850934_4852293_+	McrC family protein	NA	NA	NA	NA
WP_048268190.1\|4852314_4852938_+	hypothetical protein	NA	NA	NA	NA
WP_048268191.1\|4853372_4853852_-	hypothetical protein	NA	NA	NA	NA
WP_064362533.1\|4853926_4854706_-	hypothetical protein	NA	NA	NA	NA
WP_049239071.1\|4855544_4855835_-	membrane protein	NA	NA	NA	NA
WP_047683744.1\|4855927_4857106_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	9.1e-136	60.9
4858720:4858734	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP041514

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP041515

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection