CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP041607	Streptomyces sp. S1D4-14 chromosome, complete genome	23 crisprs	Cas14u_CAS-V,c2c9_V-U4,csa3,RT,DEDDh,WYL,cas4,Cas9_archaeal,cas14i,DinG,c2c10_CAS-V-U3,cas14j	14	14
NZ_CP041605	Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence	0 crisprs	NA	0	0
NZ_CP041606	Streptomyces sp. S1D4-14 plasmid pS1D4-14.2, complete sequence	1 crisprs	NA	1	2

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041607_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_1

1022753-1022836

Orphan

Consensus_repeat	Method
CGCGCGGGCGGGGGTGAGCCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_1

>merge|NZ_CP041607|1|1022753-1022836|CRISPRCasFinder
CGCGCGGGCGGGGGTGAGCCGGCTTCGCCGTGGTCGAAATTCACGGCGAAGGTGCTTTCCCCGCGCAGGCGGGGGTGAGCCGGC

>NZ_CP041607|1|1|1022753-1022836|CRISPRCasFinder
CGCGCGGGCGGGGGTGAGCCGGC	TTCGCCGTGGTCGAAATTCACGGCGAAGGTGCTTTCCC
CGCGCAGGCGGGGGTGAGCCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143600046.1\|1016295_1016973_+\|response-regulator	unknown	unknown	gnl\|CDD\|225107
NZ_CP041607.1\|WP_143600049.1\|1019211_1021314_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600052.1\|1026071_1026644_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP041607.1\|WP_143600042.1\|1010105_1010552_-\|DUF4265-domain-containing-protein	unknown	unknown	gnl\|CDD\|379459
NZ_CP041607.1\|WP_143600047.1\|1017102_1017516_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|198164
NZ_CP041607.1\|WP_143600051.1\|1023866_1024106_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600048.1\|1017781_1018621_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP041607.1\|WP_143600043.1\|1010818_1011382_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|223340
NZ_CP041607.1\|WP_143600045.1\|1015192_1016299_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP041607.1\|WP_143600056.1\|1029456_1030215_+\|FCD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225097
NZ_CP041607.1\|WP_054235274.1\|1024851_1025058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600055.1\|1028598_1029366_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235546
NZ_CP041607.1\|WP_054235275.1\|1024421_1024655_-\|chaplin	unknown	unknown	gnl\|CDD\|367652
NZ_CP041607.1\|WP_054235273.1\|1025167_1025818_-\|DUF4360-domain-containing-protein	unknown	unknown	gnl\|CDD\|372992
NZ_CP041607.1\|WP_143600050.1\|1021303_1022578_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600044.1\|1014293_1014980_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143605161.1\|1011822_1013052_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180297
NZ_CP041607.1\|WP_143605162.1\|1023033_1023621_-\|exonuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|99836
NZ_CP041607.1\|WP_143600053.1\|1026784_1027327_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600054.1\|1027432_1028599_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|224871

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143600046.1\|1016295_1016973_+\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	6.5683e-71
NZ_CP041607.1\|WP_143605161.1\|1011822_1013052_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|180297	PRK05868, PRK05868, FAD-binding protein.	9.91696e-98
NZ_CP041607.1\|WP_143600052.1\|1026071_1026644_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	1.20428e-57
NZ_CP041607.1\|WP_143600042.1\|1010105_1010552_-\|DUF4265-domain-containing-protein	gnl\|CDD\|379459	pfam14085, DUF4265, Domain of unknown function (DUF4265). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 139 and 168 amino acids in length.	4.95399e-09
NZ_CP041607.1\|WP_143600047.1\|1017102_1017516_+\|hypothetical-protein	gnl\|CDD\|198164	smart01096, CPSase_L_D3, Carbamoyl-phosphate synthetase large chain, oligomerisation domain. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. The carbamoyl-phosphate synthase (CPS) enzyme in prokaryotes is a heterodimer of a small and large chain.	0.004525
NZ_CP041607.1\|WP_143600048.1\|1017781_1018621_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.24042e-29
NZ_CP041607.1\|WP_143600043.1\|1010818_1011382_+\|dihydrofolate-reductase	gnl\|CDD\|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	8.35384e-19
NZ_CP041607.1\|WP_143600045.1\|1015192_1016299_+\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	7.11667e-42
NZ_CP041607.1\|WP_143600055.1\|1028598_1029366_+\|glucose-1-dehydrogenase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.69997e-87
NZ_CP041607.1\|WP_054235275.1\|1024421_1024655_-\|chaplin	gnl\|CDD\|367652	pfam03777, DUF320, Small secreted domain (DUF320). Small domain found in a family of secreted streptomyces proteins. It occurs singly or as a pair. Many of the domains have two cysteines that may form a disulphide bridge.	3.48246e-15
NZ_CP041607.1\|WP_054235273.1\|1025167_1025818_-\|DUF4360-domain-containing-protein	gnl\|CDD\|372992	pfam14273, DUF4360, Domain of unknown function (DUF4360). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 200 and 228 amino acids in length. There is a conserved GCP sequence motif near the N-terminus.	2.14664e-88
NZ_CP041607.1\|WP_143600056.1\|1029456_1030215_+\|FCD-domain-containing-protein	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	2.24258e-40
NZ_CP041607.1\|WP_143605162.1\|1023033_1023621_-\|exonuclease-domain-containing-protein	gnl\|CDD\|99836	cd06133, ERI-1_3'hExo_like, DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins. This subfamily is composed of Caenorhabditis elegans ERI-1, human 3' exonuclease (3'hExo), Drosophila exonuclease snipper (snp), and similar proteins from eukaryotes and bacteria. These are DEDDh-type DnaQ-like 3'-5' exonucleases containing three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. ERI-1 has been implicated in the degradation of small interfering RNAs (RNAi). 3'hExo participates in the degradation of histone mRNAs. Snp is a non-essential exonuclease that efficiently degrades structured RNA and DNA substrates as long as there is a minimum of 2 nucleotides in the 3' overhang to initiate degradation. Snp is not a functional homolog of either ERI-1 or 3'hExo.	8.22967e-51
NZ_CP041607.1\|WP_143600054.1\|1027432_1028599_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.66658e-111

>NZ_CP041607.1|WP_143600050.1|1021303_1022578_+|hypothetical-protein
MFHETARDPRSDRALRAQAVLPGTAGDEVKVLDPAALGGEDRVLAGALPPARGITEIKADVAERYGVTLNDGDGRWTAVEATRILEQLACVPEWDLGVLRDCWMYREGDLSSPLGRVEANSHYKWNDAKDGKNVYGYTDVKHIHFYDAAFDKRVFFEARENFPLLHELGHLRAEATLVRGNRRAFLDGVDRVLALHGEAVAQADRFVPTDADAPKVREFVLRLHGRWTSDYARLREHLESLRRDFDDLWAYTDVFERYGVSRDEMAGWGRVVNGARNACEDLGGWAYGVGKEIDEEIKAYGDLLLAKATFGTPGLRAQCLGFLKVCDMLFAETPKVLRQALAYGGSARYLEYFQWVVRASGFNPFTEYSKVSRAEWFAETYELAVLDPGELARLSGPMAEWFVTRRLAFPLHLHPYTADDLLPP
>NZ_CP041607.1|WP_143600049.1|1019211_1021314_+|hypothetical-protein
MPEGSAKIESWSPAIAAVGDDLPEPAVHRGQYVIPLGVDDQDWLRFLGISYHVAPNIGIPVSTTSFGLRVVDEELELTCQIFNETGEHVQDLVVENPKRPWGGDAVGVPLTLDRFPGTSLTFRFNYRNSVNVRDLILTLDFGDALVVALNRRSINFTLAQRPVADTTLDRRERDLPATDADTPLLYLHGYEDPDSGYETPITRVPPIALTPERIGAAWRTAKSTGWFDPAVFPNIGGAQDAAGLAGVMAALAPLDETTVVKQLLSGARLAVQRGVTGEYDYRFLDVPAHCHPGLVLVENYRLTAYPARYGAGRVIKTFSLLPGERTNIRLNTYKRSSSALQQASSILDSTNSETEQEFTNSVNREQSTQENASKNFEYRASAEAEGQATWGWGSAKAKVSGGVSGGNNSAREEFAKNLTNAVSQNAARATSRRDIQVDTSLDTKLEEGEEQAVERTLENINVSRTLNFVFRQMNQEYVSLLHLVDVRVAFFNGHAESRDEVPLGELRRLLEDCVLPERVDAVYENLLGQLRGITDHRGETRADFVEVVRDGDEPATAYARVNPDATSSYPSPDGRTLTVPGVIVGAEQHVLRTDGVVVEAFLGEGNGLDTYSTGLQEQEVRAKEAANQLRELEAERLRLALKIVSDNDEQRMRLYQQMFVRPQIVNQIDHAAMTGVPGAGVPGGADGDGTPSGTDGLRVP
>NZ_CP041607.1|WP_143600048.1|1017781_1018621_-|IS5-family-transposase
MTRQRPYPSDLSDARWELIGPTLTTWRTERRSKALDIGRPPEHDLRRIMDAILYVDRTGIAWRYLPHDFPPWETVYGYFAAWQKVGVFDQLNGLLRHLLREAEGRDGEPTACVLDAQSVKTSANVPAAGQGIDAGKKIAGRERHIGVDTLGLLLAVWVTAASVSDNVGGMHLMSHIAATHPRVTKAWADTGYRTKAIDHGARLGLDVEVVQRDPGVKGFKVIPRRWVVERTFGWLMHHRRLARDYETHPHRSEAIIHVAMIDLISRRLTRESTPNWRNT
>NZ_CP041607.1|WP_143600047.1|1017102_1017516_+|hypothetical-protein
MTKLPDNPELLKLYRNGFSDKEIAVQFDVTVQAVNMRLQQMGIKRAPFRTTAKEILEAAWPSIETRRGEFIHLNRARDLYAFLRRQLRDPALTKNQRTAAERFERLLKEHNAVLDLQPGMPGGPWVPCLVSPQTGAW
>NZ_CP041607.1|WP_143600046.1|1016295_1016973_+|response-regulator
MTVRVVVVDDETLVRAGFRVLLESETDLQVVGEAADGTEAVRVIRELRPDVALMDIRMPGINGIEAIRTLLGGPSPVPVHVLVLTTFDLDEYVFEALRAGAAGFLLKDTPPARLIDAVRVIATGESLLSPGVTRRLIETYVRRPGYTGPVTHALDGVTGRERDVLGLIAHGLSNNEIAAELYLTVGTVKTHVSRLLTKLGARDRAQLVIAAYESGLSSTWGARGT
>NZ_CP041607.1|WP_143600045.1|1015192_1016299_+|sensor-histidine-kinase
MASNVVWWTLGTHRTGWPTWQTVLTCSLGAAVAVRRLLPLPALAVASVVMATDGALSLTGVLATALLVYGVAVARPTRVAAYAGAVAGAAQLALMIPMQGITGHDYWGWPGMSQSLIVEAAAWAIGWSTRRGRAYTRGLVEQAEERAQLLLVEERMRIARELHDVVAHSLSIVAVQAGVGHHVIGSRPDEAAKSLSAIETTSRDALGELRSLLGVLRDDDGAEWLPGGLDDLNTLLEQIRRAGVQVELTISGHPHAVPRGLDRAAYRIVQEALTNVVKHARTSHARATVAYAPGEVAFTVVDAGAGRTSTPITEGHGLTGMKERAALYGGEVHAGPLSPHGFRVAARLPYAANERTAQFPVGADLEGA
>NZ_CP041607.1|WP_143600044.1|1014293_1014980_-|hypothetical-protein
MDLSRTPARRWLSPVPWGFALLAAASSLTYGGDHAVNAWASTNLANMGDHPVEALITSAFLFGADPWACLRSIALAGAILAFLVIRFGNVRAVALIAAGQVLGTLVSEGLLAARIAAGQADPALRTTLDVGPSYVIVSALAAVAVAGARRWHRWTALAALAVRAPHITSGLTTLGVTPVGHVTALSTGMLLAWGPRSSDARHRYLHRLTLRAAPLQTEERTNGRALST
>NZ_CP041607.1|WP_143605161.1|1011822_1013052_-|FAD-dependent-oxidoreductase
MSGPRVLVAGASIAGPALAHWLRRRGAEVTVVERAPELRPGGQAVDARGVAKEAIGRMGLDAAVRAACTDTAGAHTVDADGQVLETFRADDDGGDGFIADIEILRGDLSQVLYDDTRDGVEYVFGDRIAELAQDADGVDVVFAGGNRRRFDLVVGADGLHSELRAMVFGPHKRFLRHLEHVLAFYSVPNEFGLDRWLLEYRDQESGRSALLRPIQDATRAMAMFYFPSADFDVDHRDVAAQKVLLRERMAGLGWLTPDILAHLDDTPDFYLDQVAQVVMDRWSSGRVGLLGDAAFSSSPMSGQGTGLALVGAYLLAGELAAAGWDPDAGFARYEARMRSFVEANQEIGRLNARSRDLPGPDAEPRPDFASEWFTELVGRAINGVELPDYAGVPDSAAPAGSPITSSAKP
>NZ_CP041607.1|WP_143600043.1|1010818_1011382_+|dihydrofolate-reductase
MRKLIYGMNLTLDGYIAAPGDDIGWSVPSDELFQFWSDQLQATDLSLYGRKLWQTMSSYWPTGDQQPNATPAEIEFARRWRDMSKVVFSSTIDKVDWNTRLVTGDAVAEITRLKAEDGGPMDIGGATLAGAAMRAGLIDEYVLATAPVLVGGGTPFFTALDNWVNLNLVETRAFPSGVILTRYETRR
>NZ_CP041607.1|WP_143600042.1|1010105_1010552_-|DUF4265-domain-containing-protein
MMDEPNVGADTHIRLLAGHNSIGRPVFEVLPARVLGEHSFELSGSPGLVLGCAAGDVLQVADDGTFEVARRGANVCIQAYRGGPFSLEELAGLEAGLTALNGLAEAPADRRFIVGTVAREVGFPVIERVMNDWAASVDNTEWWFGNAD
>NZ_CP041607.1|WP_143605162.1|1023033_1023621_-|exonuclease-domain-containing-protein
MFPRTRQSAPHPARRRPSRWGFWAQPPGAVSEIIEIGLTVIDLDAGERLARHRTLVRPVRSTVSEFCTELTGLTPHEVDQGVSFAEACQLPAAEHRAGTRPWVSWGDYDRNQFTRQCQATRTPYPFGRHYTNAKAVFTEAYGLRKRPGMAQALEIAGRRLEGRHHRGEDDAWNIAALVLHLSERGVWPATVEHPA
>NZ_CP041607.1|WP_143600051.1|1023866_1024106_+|hypothetical-protein
MAVCQDRRPGTEAVAIAVRQIRSPSTTSDSRSPEPATVRLNGQPFARTDNHTPKPVIVRQDRWPTSLRHRFAKTDDRAP
>NZ_CP041607.1|WP_054235275.1|1024421_1024655_-|chaplin
MRIRLMAAAGLAGVALLATAGTAAADPTPVGVASNSPGVLSGNVIQIPLDLGLNLCGNSLDLLSLLNPATGNTCTNN
>NZ_CP041607.1|WP_054235274.1|1024851_1025058_+|hypothetical-protein
MPTSQPDSSSPSDDRATPDALLHTGSEGPVTAEDMVLAAGRDLSPKNLAWAERRLREDGPTAIERLLP
>NZ_CP041607.1|WP_054235273.1|1025167_1025818_-|DUF4360-domain-containing-protein
MAGGLLLGGAIAALFATALPGPDPSSGIVDPPPDKIVIKVATVNGSGCPQGTAAVAVSPDNTAFTVTYSDYLAQVGGNSDPTAFRKNCQLNLIVHVPQGFTYAIASADYRGFAALQSGASSSEKASYYFQGSSSTAAITHPFRGPYNDNWQSTDVTDWAQLVWAPCGVQRNFNINTELRVNAGTSTPGSSSFMTMDSTDGDISTIYHLAWKECPAS
>NZ_CP041607.1|WP_143600052.1|1026071_1026644_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MRRGNWLGSVVTAAVVALTAGCGGASRTPAASAAPTPGASAAIGVTSPAFGDGGTVPRRFTCDGANVSPPLRLSGVPGGAAELVVLAEDPDAASGTFVHWLMWGVDPHETALGAGAVPKGAVQGRNGFGQRRYGGPCPPAGKPHHYVFSVLAADVRLHLPGDATVDAVRRALAGHTVGSGTLVGRYGRTG
>NZ_CP041607.1|WP_143600053.1|1026784_1027327_+|hypothetical-protein
MESRHLRIGRRRIWMLSGACLLVLGPIGYFLGGWIPLTALTVSLLAATTVAHWKAASWLGPAIARGQRESRRDVATFCVVIAVSGYAQPPARPAPTAEELAALRLEAYRAAAHDDLAEDLRGLAADALAAADTAHTEDTPVAWRAARASAERLAHSAQEGNPYVRRLLIQWVEGNPAADR
>NZ_CP041607.1|WP_143600054.1|1027432_1028599_+|acyl-CoA-dehydrogenase
MDFELTEDQETIRKAVVGLLRDFDDRYWMEKDRDHRFPEEFYAAVANGGWLGLTIPEEYGGHGLGITEATLLLEEVARSGGGMNAASSIHMSIFGMQPVVVHGSEELKRRTLPRVATGDLHVCFGVTEPEAGLDTTSITTFARRDGDHYVVNGRKVWISKAVESEKILLLTRTTKVDEVARRTDGMTLFLTDLDRDRIDVRPIPKMGRNAVTSNELFIDDLRVPVEDRVGEEGQGFRYLLDGLNPERMLIAAEALGIGRVALEKAVSYGNERVVFGRPIGMNQAIQFPLADSLARLDAAELILRKATWLYDNGRPCGREANTAKYLCADAGFTAADRALQTHGGMGYSEEYNVARYFREARLMKIAPISQEMILNYLGSHTLGMPRSY
>NZ_CP041607.1|WP_143600055.1|1028598_1029366_+|glucose-1-dehydrogenase
MADNTGLFDLSGRSALVTGAAGGIGSAVAQALAHAGAAVLVTDVDGAAAAAAAEKISAAGERADSAVLDVRDRASADAAVARAAALTGGKLHILVNNAGIIAPDMFENLQEEAFRRIVDIHLMGAFHCAQAALPYLPTDGTGRIINVTSSAGIVGTLGQVNYSAAKAGIIGLTKSLARELARKQIKVNALAPLAATPMTETIRTDKKFADAMLARIPLGRWAEPEEIAGGFVFLASDAASFVTGQVLPVDGGMVM
>NZ_CP041607.1|WP_143600056.1|1029456_1030215_+|FCD-domain-containing-protein
MPGRSHPRFDALTVPKASDVLASEVRERILSGEFTEGMALPPERQLVEQTGLSRATVREALRILEVEKLLQIRPGRGGGAFVHRPGRESLASTVQLVIRGQRIRLEALHETREAIEPTCAALAAVRRTDRDLAELDAAQRDLVEAGDDIPRFLRANIDWHSAVARASDNELLIGFMSALSQSIYAATNLEQFMDAEIRSITARAHAKITDAIRDQDGPAAMRRMARHVCGFADAAARVDRRGQVELSGPTDD

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP041607_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_2

1182207-1182418

Orphan

Consensus_repeat	Method
GTCCTCCCCGCGCAGGCGGGGGTGAGCCG	CRISPRCasFinder
GTCCTCCCCGCGCAGGCGGGGGTGAGCCG	CRT
CGTCCTCCCCGCGCAGGCGGGGGTGAGCCG	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP041607_2

>merge|NZ_CP041607|2|1182207-1182418|CRISPRCasFinder,CRT,PILER-CR
TCCTCCCCCGCGCAGGCGGGGGCGAGCCGGCCAAGCCATCGACGGGGAAGGGGAGTCGGCTGTCCTCCCCGCGCAGGCGGGGGTGAGCCGTCGCGTTTGGTGACGTATGCGCTGATGTATTCGTCCTCCCCGCGCAGGCGGGGGTTAGCCGAGCACCGCCGCCGACCCGTCCGCGTGCGGCACGTCCTCCCCGCGCAGGCTGGGGTGAGCCG

>NZ_CP041607|2|2|1182207-1182418|CRISPRCasFinder
TCCTCCCCCGCGCAGGCGGGGGCGAGCCG	GCCAAGCCATCGACGGGGAAGGGGAGTCGGCT
GTCCTCCCCGCGCAGGCGGGGGTGAGCCG	TCGCGTTTGGTGACGTATGCGCTGATGTATTC
GTCCTCCCCGCGCAGGCGGGGGTTAGCCG	AGCACCGCCGCCGACCCGTCCGCGTGCGGCAC
GTCCTCCCCGCGCAGGCTGGGGTGAGCCG

>NZ_CP041607|2|1|1182207-1182418|CRT
TCCTCCCCCGCGCAGGCGGGGGCGAGCCG	GCCAAGCCATCGACGGGGAAGGGGAGTCGGCT
GTCCTCCCCGCGCAGGCGGGGGTGAGCCG	TCGCGTTTGGTGACGTATGCGCTGATGTATTC
GTCCTCCCCGCGCAGGCGGGGGTTAGCCG	AGCACCGCCGCCGACCCGTCCGCGTGCGGCAC
GTCCTCCCCGCGCAGGCTGGGGTGAGCCG

>NZ_CP041607|2|1|1182268-1182418|PILER-CR
GTCCTCCCCGCGCAGGCGGGGGTGAGCCGT	CGCGTTTGGTGACGTATGCGCTGATGTATTC
GTCCTCCCCGCGCAGGCGGGGGTTAGCCGA	GCACCGCCGCCGACCCGTCCGCGTGCGGCAC
GTCCTCCCCGCGCAGGCTGGGGTGAGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143600155.1\|1192135_1193377_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|215608
NZ_CP041607.1\|WP_143600153.1\|1185904_1186432_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600146.1\|1177912_1178974_+\|alkene-reductase	unknown	unknown	gnl\|CDD\|239243
NZ_CP041607.1\|WP_143605175.1\|1187001_1188117_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|379267
NZ_CP041607.1\|WP_143600142.1\|1174931_1175525_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP041607.1\|WP_143600157.1\|1193617_1194514_+\|tRNA-dependent-cyclodipeptide-synthase	unknown	unknown	gnl\|CDD\|275332
NZ_CP041607.1\|WP_143600147.1\|1179762_1180785_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|366154
NZ_CP041607.1\|WP_143600156.1\|1193387_1193690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600149.1\|1181636_1181942_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600143.1\|1175630_1176368_+\|NADP-oxidoreductase	unknown	unknown	gnl\|CDD\|224996
NZ_CP041607.1\|WP_143600151.1\|1182932_1183433_+\|DUF3761-domain-containing-protein	unknown	unknown	gnl\|CDD\|315295
NZ_CP041607.1\|WP_143600154.1\|1190428_1191847_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380163
NZ_CP041607.1\|WP_143600141.1\|1173844_1174684_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319
NZ_CP041607.1\|WP_143600158.1\|1194503_1195688_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_CP041607.1\|WP_143600145.1\|1176929_1177835_+\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176191
NZ_CP041607.1\|WP_143600144.1\|1176497_1176701_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600148.1\|1181379_1181640_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_099918061.1\|1178985_1179465_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP041607.1\|WP_143600150.1\|1182508_1182769_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600152.1\|1184292_1185831_-\|ISKra4-family-transposase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143600155.1\|1192135_1193377_+\|sodium:proton-antiporter	gnl\|CDD\|215608	PLN03159, PLN03159, cation/H(+) antiporter 15; Provisional.	2.02248e-58
NZ_CP041607.1\|WP_143600146.1\|1177912_1178974_+\|alkene-reductase	gnl\|CDD\|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0
NZ_CP041607.1\|WP_143600142.1\|1174931_1175525_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.75845e-10
NZ_CP041607.1\|WP_143600157.1\|1193617_1194514_+\|tRNA-dependent-cyclodipeptide-synthase	gnl\|CDD\|275332	TIGR04539, CycloL-leucyl-L-phenylalanyl_synthase, tRNA-dependent cyclodipeptide synthase. Members of this family take two aminoacylated tRNA molecules and produce a cyclic dipeptide with two peptide bonds. This enzyme therefore produces a type of nonribosomal peptide, but by a mechanism entirely different from the typical non-ribosomal peptide synthase (NRPS) that relies on adenylation to activate amino acids. Three characterized members of this family are the cyclodityrosine synthase of Mycobacterium tuberculosis (an essential gene), a cyclo(L-Phe-L-Leu) synthase from Streptomyces noursei involved in natural product biosynthesis, and cyclodileucine synthase YvmC from Bacillus licheniformis. Many cyclodipeptide synthases are found next to a cytochrome P450 that further modifies the product.	1.36712e-47
NZ_CP041607.1\|WP_143600147.1\|1179762_1180785_-\|glycosyltransferase	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	3.25113e-19
NZ_CP041607.1\|WP_143605175.1\|1187001_1188117_+\|IS630-family-transposase	gnl\|CDD\|379267	pfam13565, HTH_32, Homeodomain-like domain.	6.10965e-15
NZ_CP041607.1\|WP_143600143.1\|1175630_1176368_+\|NADP-oxidoreductase	gnl\|CDD\|224996	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only].	9.47936e-32
NZ_CP041607.1\|WP_143600151.1\|1182932_1183433_+\|DUF3761-domain-containing-protein	gnl\|CDD\|315295	pfam12587, DUF3761, Protein of unknown function (DUF3761). This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 157 amino acids in length.	1.36881e-07
NZ_CP041607.1\|WP_143600154.1\|1190428_1191847_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|380163	NF033113, halo_ClmS, chloramphenicol-biosynthetic FADH2-dependent halogenase CmlS.	1.1074e-76
NZ_CP041607.1\|WP_143600141.1\|1173844_1174684_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	1.37153e-38
NZ_CP041607.1\|WP_143600158.1\|1194503_1195688_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.72733e-53
NZ_CP041607.1\|WP_143600145.1\|1176929_1177835_+\|zinc-binding-dehydrogenase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.14987e-95
NZ_CP041607.1\|WP_099918061.1\|1178985_1179465_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	5.25965e-17

>NZ_CP041607.1|WP_143600149.1|1181636_1181942_-|hypothetical-protein
MSAQPDHAAVPPAPIAPTAAAQLLAQLRVSARAESWVPAFEQDWSRALEDSRHSYSLTPLHDVVRAWLARLEAAPAVESFLASGRDDSDGVDLADVLDGRW
>NZ_CP041607.1|WP_143600148.1|1181379_1181640_-|hypothetical-protein
MTDKPWTARLSPKALAVLDDLPEHARAMLRDVMDIAGRDPWSFPPFDSRDPEGEDVRSAAVGHLTAIYWINRPAGRLYVIDIVWLG
>NZ_CP041607.1|WP_143600147.1|1179762_1180785_-|glycosyltransferase
MISVIVAAHDLQGQLEVCLNSILNQSFRDVEVVAVLDQSAECPADLVDDYARRDGRVSVVRLTGVVGIGRIRNAGAERAAGDYLLFLDSDHIIGGETLQAMGDQLQSADEPDVLLFGHTRLHRGRAWSGAAVGLLARQGREPFASIDQPELFGAPAYSWDRLVRRDLWIRQELAFPDGLHEEVTVVHRAMLATDRVAVLKWNCVQIRRRHTQHPAGSPDGTHFDVFGRYEESFDLLKERDALDVVAPFLFTRMIRHYLFLLNLEGCLSRSERPQFFERASEHYRRFLPDGYEHPEGREGVKFQLVASGRFTALKAASLPQQARSFVSRSAAVRGRQPQAG
>NZ_CP041607.1|WP_099918061.1|1178985_1179465_+|winged-helix-turn-helix-transcriptional-regulator
MPAPTPHTPSTASEGPMSYAIFQLARAHRARAAAMLREMDLHPGQELLLMHLLDRDGQTQSELLESVGLDHSTVSKSLRRMQDAGLLIREPAEHDRRVMVVHLTDKGRAMREPLAAMWRALEETSALNLSAQQAESFVRIAYAIADAINSRALPREESE
>NZ_CP041607.1|WP_143600146.1|1177912_1178974_+|alkene-reductase
MLNSLWTPTTVGGISLPHRLVMAPMTRDRSTPEGVPTELNAEYYAQRASHALLITEGTQPSADGQGYLLTPGIHNDEQIAGWRKVTDAVHAADGRIVIQLMHTGRIAHPDNTPHGRQPVAPSAIRPAGAMFTASGPQEMPTPRALSTQEVAATVDDFRRAAAAAVAAGADGVEIHGANGYLVHQFLSDNTNQRTDRYGGSLDNRIRFAVEVAAAVADEIGADRTGLRISPGNPYNDIAEADTAELYPALLRALSPLGLAYLHVMHAGDEELLGTLRALWPTTLILNRAGTDLPTRAKDVDNGTADLVSVGALALANPDLVERLRSDAPLNTPDPATFYGGGVAGYTDYPTHTV
>NZ_CP041607.1|WP_143600145.1|1176929_1177835_+|zinc-binding-dehydrogenase
MKTILFDRFGGTEVLHEADIEVPQPGPGQIRVRVRAAGLNALDGKIRSGAMQAAFPTPLPAVPGAELAGVVDALGEGVQDVQVGDEVLGWSDTGSYAQYALATTVAPKPAGLDWQHAVALPVAGETAERVLNLLGVKAGETILMHGAAGAVGTLAVQLATARGARVIATAGPANQDYLTSLGATATVYGEGLVERVRALAPDGVDAVFDLAGKGALEDSIALRGGTERIVTIADFRAHQLGITFASGGQERSAARLAALAQDAATGKIVTTVTAYPLDQAATAQQVSDAGHIRGKLVLTVD
>NZ_CP041607.1|WP_143600144.1|1176497_1176701_+|hypothetical-protein
MGEQAWRESGLGAPADQEELQRQVSRLEQANTELLARLEERDAELEAARAAIRELTRALNQKGAADR
>NZ_CP041607.1|WP_143600143.1|1175630_1176368_+|NADP-oxidoreductase
MKITVIGAGAIGGNLAAKLSTAGHDVQVADARGPEAVRAEVLESGARAADLADAVQGRDVIVLSIPFGVAGQLADLFASVPDETVVIDTSNYYPGMLSEPIEAVDNGQVESVYTAELLGRPVVKAWNAALAETQRTKGVPAGTPGRLAIPVAGDSEEARKVAMSLVDDTGFDPYDAGTLADSWRQQPNGPAYCTELTLDELPTALAAADRVKDAAIRDSLPERFAALPANPTVDDVVEMNRAAHR
>NZ_CP041607.1|WP_143600142.1|1174931_1175525_+|TetR-family-transcriptional-regulator
MSAGELRGRKPRADVQRNRVALLETAQRHFLQHGVGTSLEAVAKEAGVGPATLYRHFPTREALLAAVLQTRSEELVARQADIEQLGDPAEALEQWLRAMEEYFSAFSGLPDPLMAAARAQEPDNPLTIPCDILIAATDQYVRAAQLAGRVRASVQGHDLFLAACSIAWIKGTGTEEESLDRLRMLIASGYRERDTQA
>NZ_CP041607.1|WP_143600141.1|1173844_1174684_+|helix-turn-helix-domain-containing-protein
MDKKELAEFLRHRRETLRPRDVGLVEGPRRRTQGLRREEVAQLAGMSTDYYARLEQQRAPQPSVQITTALARALRLTLDERDHLFVLIGHNAPARFQRSEHVSPTLMRVLDRLDDSPALVQTDLLDTLAMNPLAVALLGDQTRHTGLARSGYYRWFMDPAERLVYPEETHERHGRAQAARLRAALTSGSDTPRAAQILAELQEHSPEFVRMWELQEVAQRYDDCKTILHPELGRIDVDAQVLFTENRAQTLVVLTTRPGTESDSKLELLSVIGHQQLTP
>NZ_CP041607.1|WP_143600150.1|1182508_1182769_+|hypothetical-protein
MKAIWTLLTLLFGVLTLGAIANAIQSLTGAGASGAHNSYSISTGIIDGALQLLFIALLALATRACYRRASRGNQPRPGADRRPWER
>NZ_CP041607.1|WP_143600151.1|1182932_1183433_+|DUF3761-domain-containing-protein
MSYNQPPPPPGYGPPAAPAQQPPRPKWGRKRYMLPAIGFAFFLGIGAGGSSSQDTNTTKAAASTVQPTATVTATATATETATPKPAPTVTATETVKVKVTVTAKAASGSGSGSSGGSSGSSGSSSSGGSSAAGNGATALCNDGTYSYAAHHQGACSHHGGVAVFYK
>NZ_CP041607.1|WP_143600152.1|1184292_1185831_-|ISKra4-family-transposase
MEQYDALSEPDPYVASRDAFECLVSTLAGAPARSMAHDELELLLERQGRELLRQLIQDHLDMRARNEEDAVRTGGGQPVVRGPEGQERTWREKGHRRWLTCVFGPVRVTRIAYRGRGVSNVHPADADLSLPAGRHSRGLARLAVLEAVRGSFDQAAAAIERRCGRVLGKRRLEELVVAAAVDIAAYYTVKIPTPCTREMPLVIQVDGKGVVMRPEALREATRRAAAQSAAAGRRGRLAPGEKPNRKRMATVACVFDTAPAPRRPHDIVHPPGGRSETRQPRPGPKAERKWCTASVIRPPEQVVSDAFAQAEARDPQHLRDWIVLVDGARHQLDLIHTEAARRGIRLNVLLDFVHVAEYCWTAAHAFHPPGSREAETWAADKLTAILAGHADRAATEMTAQAAAEQLPAARRDAVTTCHRYLTGHLDQLHYDTALTAGWPIATGAVEGACRHLIADRLDITGARWGLNGAEAVLQLRALITNNDFEDYWNFHSAREHQRLYPSPDQRNYSLTA
>NZ_CP041607.1|WP_143600153.1|1185904_1186432_-|hypothetical-protein
MVSLPEELQAREAAARQRVEELQAEAAELAVRLERAREDLSRLEITRETVAQVLADLSAAEAAPDGPAHDVPESEETSAPHGIGVMAVPPWREGLVAQVLPDVYRDIVEIVADAPGPLQAKQIVPRIGLEATTAKIEGTRGKLKRLVERGWLDEDAPGRFTLARHGPDADRVNSQ
>NZ_CP041607.1|WP_143605175.1|1187001_1188117_+|IS630-family-transposase
MKKMAYGHKTQHRARQRATVVLLAARGRGNARISAETLLYVDTVRTWRGRFADGGLPALADRKRSGRPARFTPVQVAEAKALACQLPAETGIPLSRWSCPELASELTARGITDSISASTVRRWLREDALKPWQYRSWIFIRDPDFRARAQRVLDLYARTFEGVPLGEDEYVLSSDEKTSIQARCRCHPALAPGQTRAMRVNHEYGRGGALAYLVAYDVHRAEVHGRCESTTGIVPFMAPVEQVMTQEPYAGAKRVFWIVDNGSSHRGRRSIDRMAARFPNAVLVHTPVHASWLNQIEIFFSIVQRKVVSPNDFTDLAEVRERLRGFEDRYNATAQPFQWRFTTSDLDDLLARLDRHTPADRQGESSVTPAA
>NZ_CP041607.1|WP_143600154.1|1190428_1191847_+|FAD-dependent-oxidoreductase
MAAARLGLLVGIPAEAALVPSSAADCRAVHRRQRLCQVFPEAAQRPPTSGTADRIHHEADRSYEISIDEQYDVIVVGGGPAGAVTAGLLAKDGRRVLLLEREKFPRYHIGESLNPGLVPALERMGLRERLDEIGYLRKYGATFVWGAGVEPWDFRFNEGSPYEYVHQVRRADFDALLLARARELGAVVVEEATVKDIVQDGERVTGVTYQTKAAVTPRTARCRMLVDASGQQHLLARRFDLLNWHDDLRNIAVWSYWQGCELYAGNRAGDTLVENLPEGWIWYIPLADGTVSIGYVTPVEQYKKAAPQNAEAFLHEQLTRTCEVSRLTRNAVQVSGVRTIKDWSYQATRFQGPGWALVGDAAAFVDPLLSSGVTLAMRAAERLADGLGRVLDHPESEEEVLTRYEKNYQEFLGVILEFVRVFYDRTRLKEEYWDEAQRAIDPDALLNSKVDFVTLISGLFGTAEIFDPVDVP
>NZ_CP041607.1|WP_143600155.1|1192135_1193377_+|sodium:proton-antiporter
MTGSTVADFFLALSLVLGAAHFFGGLARRVGQPAVVGEICAGLLASPMVVTTADAEAVLPVEVKPLLGALANVGLATFMFLIGYELDGGFLRDRRGAALGVAAGSVVVPMAAGVALAVPLADTYAPGNHTAFVLFVGVAMSVTAFPVLARILADCGLNRHSVGSLALASAAIGDLVAWIGLAGVVAYASAFGQWQMALLPVYLVLMLAVVRPVLAAVVRRVQDRDRPVERLIPLLVAGLMLSCAATEWLGIHFIFGAFAFGAVMPRNVLGTLRTQIMRQMEQVGHILLPLYFVVAGTKVDLSTFTPASVLTLIAVIGVAVLSKAGGAYVGARLSGLAHSVAMPIAVLMNTRGLTEIVILAVALEKGLIDQSFYSMMVVMAVVTTAMTGPLLRLLGVHLRPTTGSRPAPSLELG
>NZ_CP041607.1|WP_143600156.1|1193387_1193690_+|hypothetical-protein
MLRSPVGRSRRTGPASCCTELLSISAFARRVGLATSALRSYDGCRVLPGRLGVESTTRAALDLASGQLCIEPGSGLLCSGVPCPCPASGPQGNSRFPRTV
>NZ_CP041607.1|WP_143600157.1|1193617_1194514_+|tRNA-dependent-cyclodipeptide-synthase
MQWRPLSLPGIGAAGQLPVPPNCVRGVAEVKLRRDISLCRDRDADTNSSGDFVFSPAPRHAGADPAAAQTVVRIRVHRERCRRVLEKRHCAVLGLSPFNSFFTPRTIRLLVAWADDWFDQVEILLPGYEAAYGQIAAGMAPRAAVRHTLHAVRTLRGAAKTALARVGREPRVHTWTAKAAHPHYQALHRAGIDAFHREPLFRDLCEQNARAYLRTVTDRVPDADTVARNVDYILAEVPYLLDVAGIVDAESAVFCYPKPWPLQLALFDGHVPTLVPADRHGYAQVTLDAVQPEGPHVR
>NZ_CP041607.1|WP_143600158.1|1194503_1195688_+|cytochrome-P450
MCADILDWPLPPGPHGTPPPLYETLRRKRPVCPVRMPSGEVMWLLTRREDICAVATDHHRFTRNLTYPGAPRIAGEDFNSVKGGIFNLDPPDHTRIRTILTPYYTRAAVTRYAGTIRALAHALLDEMIQGPNPADLMTGYAEPLALRFNCDMLRIPLALRTRYRDCFRTQTSQTASRAAIADATAQISALARTVLDAHNGSAADHPIGALLAAHREGTISEEELIGTVDYLMVTGVDPLISPTGTFVVTVLRHHGHRGRLIADPDSWPATIEELLRYHHNGYLSNPRVATEDITLHGQTIHAGQAVITPFLAACWDPDRYPKPGKFDPGRSTDGSLTFGHGAHYCLGSSLARLYLDIALRELFARLPDLTLAVDDIPWDENILFTRPALLPVTW

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Crispr_ID: NZ_CP041607_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_3

1413987-1414503

Orphan

Consensus_repeat	Method
CGGCTCACCCCCGCCNNNGCGGGGNNGA	CRT

8 spacers

The CRISPR arrays of NZ_CP041607_3

>merge|NZ_CP041607|3|1413987-1414503|CRT
CGGCTCACCCCAGCCTGCGCGGGGAGGACAACGCCGCCGTCGCCGACATCGACGTGATGGCCGGCTCACCCCCGCCTGCGCGGGGAGGACGGAATCGGGCTGAGTCGAATGCTGGGAAGCGGCGGCTCACCCCCGCCTGCGCGGGGAGGACGCATCGCGCAGGACGTGAAGGATCAGGTCCGGCGGCTCACCCCCGCCTGCGCAGGGAGGACCGAAGCTTCAACTCGCGCGGCTTTGCTGCCGCCTGGCTCACCCCCGCCTGCGCGGGGAGGACGAGGAGGACGAAACCGACGGTGTAGCAGAAGACGGCTTACCCCCGCCTGCGCGGGGAGGACGGCGCGTGGCAGGCCCGCTCATCGCGTCCCTCCGGCTCACCCCCGCCCAGGCGGGGGTGAGCCGCCGGGTACAAAGAGTGATCCTCCCAAGACCCTGTCCTCCCCGCGCAGGCGGGGGTGAGCCGTCGTCCCGGAATTCTTGCCGTTTCGTTCTTCGGTCCTCCCTGCGCAGGCGGGGGTGA

>NZ_CP041607|3|2|1413987-1414503|CRT
CGGCTCACCCCAGCCTGCGCGGGGAGGA	CAACGCCGCCGTCGCCGACATCGACGTGATGGC
CGGCTCACCCCCGCCTGCGCGGGGAGGA	CGGAATCGGGCTGAGTCGAATGCTGGGAAGCGG
CGGCTCACCCCCGCCTGCGCGGGGAGGA	CGCATCGCGCAGGACGTGAAGGATCAGGTCCGG
CGGCTCACCCCCGCCTGCGCAGGGAGGA	CCGAAGCTTCAACTCGCGCGGCTTTGCTGCCGCC
TGGCTCACCCCCGCCTGCGCGGGGAGGA	CGAGGAGGACGAAACCGACGGTGTAGCAGAAGA
CGGCTTACCCCCGCCTGCGCGGGGAGGA	CGGCGCGTGGCAGGCCCGCTCATCGCGTCCCTC
CGGCTCACCCCCGCCCAGGCGGGGGTGA	GCCGCCGGGTACAAAGAGTGATCCTCCCAAGAC
CCTGTCCTCCCCGCGCAGGCGGGGGTGA	GCCGTCGTCCCGGAATTCTTGCCGTTTCGTTCT
TCGGTCCTCCCTGCGCAGGCGGGGGTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143600302.1\|1429250_1429814_-\|GNAT-family-N-acetyltransferase	unknown	unknown	unknown
NZ_CP041607.1\|WP_143605203.1\|1408910_1409900_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP041607.1\|WP_143600151.1\|1412971_1413472_-\|DUF3761-domain-containing-protein	unknown	unknown	gnl\|CDD\|315295
NZ_CP041607.1\|WP_143600289.1\|1407556_1408390_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367959
NZ_CP041607.1\|WP_143600300.1\|1425630_1426947_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP041607.1\|WP_143600290.1\|1409968_1410382_-\|transposase	unknown	unknown	unknown
NZ_CP041607.1\|WP_054235232.1\|1413635_1413896_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_099925055.1\|1419942_1420173_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600295.1\|1417370_1418054_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367243
NZ_CP041607.1\|WP_143600298.1\|1421612_1422611_+\|DUF1259-domain-containing-protein	unknown	unknown	gnl\|CDD\|377846
NZ_CP041607.1\|WP_143600299.1\|1422924_1423170_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600291.1\|1410929_1411175_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600296.1\|1420169_1420385_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234688
NZ_CP041607.1\|WP_143600292.1\|1411174_1411396_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600293.1\|1411728_1412727_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_CP041607.1\|WP_143600287.1\|1406208_1406532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600297.1\|1420421_1421372_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|185715
NZ_CP041607.1\|WP_143600288.1\|1407136_1407418_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600301.1\|1427035_1428013_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238042
NZ_CP041607.1\|WP_143600294.1\|1415864_1417220_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143600295.1\|1417370_1418054_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	2.22508e-09
NZ_CP041607.1\|WP_143605203.1\|1408910_1409900_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.66331e-26
NZ_CP041607.1\|WP_143600300.1\|1425630_1426947_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.5998e-35
NZ_CP041607.1\|WP_143600294.1\|1415864_1417220_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.08783e-60
NZ_CP041607.1\|WP_143600151.1\|1412971_1413472_-\|DUF3761-domain-containing-protein	gnl\|CDD\|315295	pfam12587, DUF3761, Protein of unknown function (DUF3761). This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 157 amino acids in length.	1.36881e-07
NZ_CP041607.1\|WP_143600289.1\|1407556_1408390_-\|hypothetical-protein	gnl\|CDD\|367959	pfam04484, QWRF, QWRF family. AUG8 belongs to the plant QWRF motif-containing protein family, which also includes microtubule-associated protein ENDOSPERM DEFECTIVE 1 and SNOWY COTYLEDON 3. AUG8 binds the microtubule plus-end and participates in the reorientation of microtubules in hypocotyls (the stem of a germinating seedling).	1.9886e-05
NZ_CP041607.1\|WP_143600298.1\|1421612_1422611_+\|DUF1259-domain-containing-protein	gnl\|CDD\|377846	pfam07485, DUF1529, Domain of Unknown Function (DUF1259). This family is the lppY/lpqO homolog family.	6.32432e-42
NZ_CP041607.1\|WP_143600293.1\|1411728_1412727_+\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.00115162
NZ_CP041607.1\|WP_143600296.1\|1420169_1420385_+\|hypothetical-protein	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	5.63099e-15
NZ_CP041607.1\|WP_143600297.1\|1420421_1421372_-\|hypothetical-protein	gnl\|CDD\|185715	cd07906, Adenylation_DNA_ligase_LigD_LigC, Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases. Bacterial DNA ligases are divided into two broad classes: NAD-dependent and ATP-dependent. All bacterial species have a NAD-dependent DNA ligase (LigA). Some bacterial genomes contain multiple genes for DNA ligases that are predicted to use ATP as their cofactor, including Mycobacterium tuberculosis LigB, LigC, and LigD. This group is composed of ATP-dependent DNA ligases similar to Mycobacterium tuberculosis LigC. ATP-dependent polynucleotide ligases catalyze phosphodiester bond formation using nicked nucleic acid substrates with the high energy nucleotide of ATP as a cofactor in a three step reaction mechanism. DNA ligases play a vital role in the diverse processes of DNA replication, recombination and repair. Members of this group contain adenylation and C-terminal oligonucleotide/oligosaccharide binding (OB)-fold domains, comprising a catalytic core unit that is common to all members of the ATP-dependent DNA ligase family. The adenylation domain binds ATP and contains many of the active-site residues. The common catalytic core unit comprises six conserved sequence motifs (I, III, IIIa, IV, V and VI) that define this family of related nucleotidyltransferases. LigD consists of a central ATP-dependent DNA ligase catalytic core unit fused to a C-terminal polymerase domain and an N-terminal 3'-phosphoesterase (PE) module. LigD catalyzes the end-healing and end-sealing steps during non-homologous end joining.	1.50186e-38
NZ_CP041607.1\|WP_143600301.1\|1427035_1428013_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.44606e-08

>NZ_CP041607.1|WP_054235232.1|1413635_1413896_-|hypothetical-protein
MKAIWTLLTLLFGVLTLGAIANAIQSLTGAGASGAHNSYSISTGIIDGALQLIFIALLALATRACYRRASRGNQPRPGADRRPWER
>NZ_CP041607.1|WP_143600151.1|1412971_1413472_-|DUF3761-domain-containing-protein
MSYNQPPPPPGYGPPAAPAQQPPRPKWGRKRYMLPAIGFAFFLGIGAGGSSSQDTNTTKAAASTVQPTATVTATATATETATPKPAPTVTATETVKVKVTVTAKAASGSGSGSSGGSSGSSGSSSSGGSSAAGNGATALCNDGTYSYAAHHQGACSHHGGVAVFYK
>NZ_CP041607.1|WP_143600293.1|1411728_1412727_+|hypothetical-protein
MARRDFEKILSELGEIRRTVDDRAIGLAALHKDQEDLRRKVLETVLQGTTGLREENRELRRRQEKMLTDLADTRSGVEALRRELAQAFTHIVGVPVPWAADDSASAFELLQHEPQPLEAADVDSSNGWRGEAVHEVTGPADDGDGKREEQRDEQPDPGEAPEAAAEPAPGASASAPPGPAAPEPPPDSAIASSEEDEQRRREDHRQHVESVLSAAAIASARVICHRDTWSFLIEQTSQHPHFRLPEHINDLDDGKIETFLSGRSVLAVLVTMRKVRDDHLAGDEHMATWALAAAVYRRTQLAVKDTAHTRPDDAGVTTIVLDDRPITIGEAA
>NZ_CP041607.1|WP_143600292.1|1411174_1411396_-|hypothetical-protein
MSQEPSARQPLEPAAADAVRAYAARTRADADRFASALEDIAANGLPAVEECTPWEELPEAHLARLATQRPAVA
>NZ_CP041607.1|WP_143600291.1|1410929_1411175_-|hypothetical-protein
MTGRRRAQIAFSDSAAKQLENLTDEHQIHALDRALVAIFVDPEIGEPIPGDTTHPELRQYADEIERVRVLYFVTALRTGVI
>NZ_CP041607.1|WP_143600290.1|1409968_1410382_-|transposase
MASTNDHGTPDPQVEARSTGPRRYTAEYKARILAEYETLDKKGKGALLRREGLYSSLITTWRQQRDKGALDALAASAGRPKADPRDTEIEKLKAEKARLEADLAKARTVIEVQGKLSALLDQFATDSVPTRNGEKNQ
>NZ_CP041607.1|WP_143605203.1|1408910_1409900_-|IS3-family-transposase
MVGRVQACAALGVSRATYYRQHRRSPAPAKPRPERRRHARALTPEEEIRILDVLHSPEFADMAPAEIYAVLLDRGVYLCSESTMYRLLRRHGEVRERRRQAVHPPRTVPELVAEGPNRVWSWDITKLKGPVKGVYYCLYTIIDIFSRYTVGWMIAAHENKDLAERFLSESIAKYGIEPGQLTIHSDRGSPMVAQNVAQMMAGLGVTKSHSRPKTSNDNPYSESQYKTLKYRHDFPERFGSLEDARAWCTQFFTWYNEEHRHSGIGLHTPYDVHFGLAEHLREMRADVLQAVYAKHPERFVRKPPEPPKLPAAAWINQPAPDGPLIPAQR
>NZ_CP041607.1|WP_143600289.1|1407556_1408390_-|hypothetical-protein
MPSCSPPATGSGFTTPPTPRTARSAGMTSPRAARSWPSAGPSARASATGATPGTGWSGRTIATGLWPPPPRTSSPGTPTTTRAASTGTPTSLSADAIDTPGQGVNREPCRRGKAHAWRARYVGSLTGLRHGTAVMGGDAMRIRFGRRTGKLAIVGTLTVAALSLATGGAFAATPPTGAEACPSGNVCLYFNSPQYGWGAWEDWSPGQSLSLSDFKFAHWGNSSGYGQTVYDHAASIVNNTGHTVVVESDLGHDDYYVAGYAGSLTSFTYNHDALLYC
>NZ_CP041607.1|WP_143600288.1|1407136_1407418_+|hypothetical-protein
MEAFGWYLYRRFAQWSRDRGLSAYERSSSDKGVGRAPMPPVGNPELALVLAGVPDSLAQTGGDLYAVINRCRGRRQPGQAGARRTAPCGRCCC
>NZ_CP041607.1|WP_143600287.1|1406208_1406532_+|hypothetical-protein
MMRPPAAGRARRLLGGWREDVGTAQLGSGRRPGDGQGTRGGGPGREQRERAVEVALDALRRAGGHRRGLAAELAREHGGVDRSWQRAVNEARVVYEREQSAEPGTPP
>NZ_CP041607.1|WP_143600294.1|1415864_1417220_-|serine-hydrolase
MSHDALAEFVEEKAKELGIPGAAVGVRVDGRELTVCHGVTNIDNPLPVDRDTLFVLGSVTKTYTATAIMRLIEQGRVELEAPVRRYVPELRLPDQDAAAQITILNLLNHTAGLDTRMVFDSGDGDDALAREVTNMAEVALIGPVGGRASYSQLGYNLLGRVVENVTGETYEAAVASLVLEQAGMTDSVFTAGQAITRRFAVGHNLSEGALKVARTWKDTRGNNPGGGLVSSVSDQLRWARFHLGGGDLARRMQEPTVELHGSTLGDAIGLGWFLRDVDGVRTVGHGGSTNGQFANLLLVPERDFAVVAASNAGPDNGLEFNQAVLRWALEHYLGVVERDPDPLPYDPQRAQEITGHYENEFMTLIIDTDGDTMTVECRIKPEIRAAADRELPADLPPASLGLLPGSGDEYIVTGGGLIGQRGFLTRDADGAIIGADMAGRFFNRVSSTPSE
>NZ_CP041607.1|WP_143600295.1|1417370_1418054_+|TetR-family-transcriptional-regulator
MPRNTLTREQILTAAITLLDAEGLEGLSMRALGQRLGSAATAVYWHVGSKDNLIALAGDQLWHEIALPDPDGVGWRTAATIMASDLYTMLTRHPWLLQAFGSLLMFGPGKARHDDHLLAIYEAAGFAGPAADQAAAAVFTFVLGNALGPAATASLTRKLRREGSGDAEQAIGEAQAEAREIAAQFPRLRARLDTHSVDYGAAPDNTFQIGLHAILDGLEALQRGPTR
>NZ_CP041607.1|WP_099925055.1|1419942_1420173_+|hypothetical-protein
MEHAPFPPDLIELQAEWQLTYAALAVPHPVHTTALRRRLQTLSGRLLFHPYWSGPGRTPAARVELRRQARAVGWQP
>NZ_CP041607.1|WP_143600296.1|1420169_1420385_+|hypothetical-protein
MNRRPEHLTAREEQILRCIRRWIEERGEGPSARQLADDIGLSSTASVAYHLGNLEERGALVRDWRTCRLVR
>NZ_CP041607.1|WP_143600297.1|1420421_1421372_-|hypothetical-protein
MVPPFDLPVPLALCRSVDHVRGHPHTAAIEPKFDGLRCQVLAGAGRLWSRHGTDLSASFADIAEASRALPDCVLDGELVAVLDSGELAFGKLQSRSGRGPRSHEGFTVHLAAFDVLAVGDTDWRPKPYAERRGRLLDLLEGGPPAIRPVPVTDSVATALGWVGALGGVEGVVMKPNRPYVAGRGSGWLKWRQMHTSEAAVLGVSGRTPATQCLILGLPHRGGRMRAVGVSLPLGQAVRHELLPLLRPAGDTEAELPGTVGGLPGADPVYYRPVIPDVVVEIEADQTGPRELGRFRHRPRVLRVRGDLTADNLPCAP
>NZ_CP041607.1|WP_143600298.1|1421612_1422611_+|DUF1259-domain-containing-protein
MDDERPQDTRTRLTASRRRVLAAAALAPVLTGVPAGARALSAGPQDRALVEPVMTKLADWVEVGEALGRPGDIKRFMYHTGLPRGDLTVFSRGIRINPALVLGSHVSFVRYADHSTLLMGDAVVTECELQHFGDVLQKHGIMQTAIHKHLLAHKPDVWWVHLHAHGHNPVTVARGLRAAFDCTGTPPAEPATSSPPVDLDTAAIDAAMGVKGTTDGEIYKCTYVRRETVADGPVILPPGLGTTTSVNFQPLGGGRAALSGDLVMIAQEVQPALMALRHGGVELVEMHHHNLTDEPRLFFVHYWAVGDAVSLAKAVRRAVDTTNVVPMPGGAA
>NZ_CP041607.1|WP_143600299.1|1422924_1423170_-|hypothetical-protein
MSDPTGAADQAVYRRRALLHIHGSGQSIGLQQNLAAWVLASPWRGMTLYPLHGPVAIAGRSQDGGVAPLDDDLAQHVRAVA
>NZ_CP041607.1|WP_143600300.1|1425630_1426947_-|MFS-transporter
MTPTAEPAQGNHRATYREVLAEPRFRLLFSTRTVAVTADALRITTFSVLVFSATGSALLSALAFGIGFIPQLFGSLLLGSLADQLPPRALITGGYALTCAAALLLALVRMPIAASLGVVALVALATPVFHGASSRLVAQSLEGDAYVLGRSLNNIASSGAQLFGLALGGAAVAVLGPHRALAVSAALYLGCALAIRIRLPRLQPGEFGGTPGSARGDGGPVRASLHGAGLLLRGRTVRRLMLAQWLPSAFVAGAEGLIVAYAGGRHFAPGWYAVLLGCLPVGMLVGDLLVGRLLRPPTRERLVVPLIALMGLPLVGFAAEPGVGVSSCLLLLCGFGFAYGLGLQRPFLDALPQDGQGQAFGLLGSGNMTLQGVGPACFGSVAAGVGTGGAIALAGSAAALTAGWILTWQPPTTPVPVPNYSTGSENGAEQHACSAPAR
>NZ_CP041607.1|WP_143600301.1|1427035_1428013_+|helix-turn-helix-domain-containing-protein
MLRFEVSVEDLLRSRFALSPALDLCLLLRSLAGQGQPLPRAWAARLMPAFERLRRETELDAALALQAPHGGPNFVAPPPRGLNQTWADDLAVIRATPLEAARHEFAATATGPSARDPRVRAVLDSADAVSRIAEAMDQAWHELLAADWSQLRAICERDVVHRVGVIGEHGWAATIESLHPGVAWRAGGIEIGFFRGGTVRLAGDGLLLIPSVFVGHIAAQVEDPWPRTLVYPARGTAALWGEQETVPQPDALAALVGRARARLLLALDAPASTSHLARSLAMAPGAVGDHLAILRGAGLLVRARSGRSVLYRRTPLGEALVGGTG
>NZ_CP041607.1|WP_143600302.1|1429250_1429814_-|GNAT-family-N-acetyltransferase
MTTTPTIKLRSFNQLAPVRDDLIAVYSDVRAELLHLPNYAIPAFAERLDRHGNAPGWAAVLAYTDDGEAVGYAYGNVIDSDDRWWKRVTPIPASEYTDRPAVALKELGARVPWRKTGTARRLHDSLLAEYVNEPYVTLMVNPAAGDGKVQRLYESWGYWSIGTSQPSPESPVLTVMIRPTLGRSSLA

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Crispr_ID: NZ_CP041607_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_4

1779859-1779978

Orphan

Consensus_repeat	Method
CGGATGATTGCCGGACCGGCCGCACGTGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_4

>merge|NZ_CP041607|4|1779859-1779978|CRISPRCasFinder
CGGATGATTGCCGGACCGGCCGCACGTGGCCGCCGGACCCGGCCGTACGCGGTCACCGTACCGACGGTGCGCGGTTACCGGACCCGGTATCGGATGATTGCCGGACCGGCCGCGCGTGGC

>NZ_CP041607|4|3|1779859-1779978|CRISPRCasFinder
CGGATGATTGCCGGACCGGCCGCACGTGGC	CGCCGGACCCGGCCGTACGCGGTCACCGTACCGACGGTGCGCGGTTACCGGACCCGGTAT
CGGATGATTGCCGGACCGGCCGCGCGTGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_097283304.1\|1788615_1790235_+\|acyl-CoA-synthetase	unknown	unknown	gnl\|CDD\|236100
NZ_CP041607.1\|WP_097283297.1\|1772595_1772961_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_060902537.1\|1787627_1788428_-\|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl\|CDD\|181122
NZ_CP041607.1\|WP_143600520.1\|1790483_1792028_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|181381
NZ_CP041607.1\|WP_097283298.1\|1773019_1774024_-\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224296
NZ_CP041607.1\|WP_143600521.1\|1794700_1796251_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236215
NZ_CP041607.1\|WP_054232933.1\|1786436_1787378_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|224462
NZ_CP041607.1\|WP_054232932.1\|1785380_1786436_-\|lipid-transfer-protein	unknown	unknown	gnl\|CDD\|181173
NZ_CP041607.1\|WP_143600519.1\|1783021_1783636_-\|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|378696
NZ_CP041607.1\|WP_143600517.1\|1770543_1772535_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|376556
NZ_CP041607.1\|WP_143600518.1\|1778227_1779247_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274928
NZ_CP041607.1\|WP_143600515.1\|1767336_1768839_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600516.1\|1769072_1770215_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|366736
NZ_CP041607.1\|WP_097283306.1\|1792213_1794637_+\|penicillin-amidase	unknown	unknown	gnl\|CDD\|376618
NZ_CP041607.1\|WP_060902539.1\|1784217_1785384_-\|thiolase-domain-containing-protein	unknown	unknown	gnl\|CDD\|181378
NZ_CP041607.1\|WP_054232928.1\|1779263_1779761_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143600514.1\|1765825_1767256_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|369272
NZ_CP041607.1\|WP_143600513.1\|1763357_1765379_-\|phospholipase-C,-phosphocholine-specific	unknown	unknown	gnl\|CDD\|274561
NZ_CP041607.1\|WP_054232930.1\|1783891_1784134_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP041607.1\|WP_143600512.1\|1762325_1763339_+\|inositol-2-dehydrogenase	unknown	unknown	gnl\|CDD\|275173

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143600518.1\|1778227_1779247_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274928	TIGR04027, Luciferase-like_monooxygenase, putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family. This protein family consists of luciferase-like monooxygenases (LLM), and include KPN_01858 from Klebsiella pneumoniae as a representative member. Most are from species that lack F420 biosynthesis, so the family is likely to bind FMN as its cofactor. This family is closely associated with a binding protein-dependent ABC transporter, suggesting a role in catabolism. [Unknown function, Enzymes of unknown specificity].	1.31054e-31
NZ_CP041607.1\|WP_060902537.1\|1787627_1788428_-\|crotonase/enoyl-CoA-hydratase-family-protein	gnl\|CDD\|181122	PRK07799, PRK07799, crotonase/enoyl-CoA hydratase family protein.	3.04715e-153
NZ_CP041607.1\|WP_097283298.1\|1773019_1774024_-\|LuxR-family-transcriptional-regulator	gnl\|CDD\|224296	COG1378, COG1378, Predicted transcriptional regulators [Transcription].	3.61104e-10
NZ_CP041607.1\|WP_143600521.1\|1794700_1796251_-\|AMP-binding-protein	gnl\|CDD\|236215	PRK08276, PRK08276, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP041607.1\|WP_054232933.1\|1786436_1787378_-\|DNA-binding-protein	gnl\|CDD\|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	1.27471e-23
NZ_CP041607.1\|WP_054232932.1\|1785380_1786436_-\|lipid-transfer-protein	gnl\|CDD\|181173	PRK07937, PRK07937, lipid-transfer protein; Provisional.	0
NZ_CP041607.1\|WP_143600519.1\|1783021_1783636_-\|CGNR-zinc-finger-domain-containing-protein	gnl\|CDD\|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	1.32895e-08
NZ_CP041607.1\|WP_143600517.1\|1770543_1772535_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	2.09346e-30
NZ_CP041607.1\|WP_143600520.1\|1790483_1792028_-\|AMP-binding-protein	gnl\|CDD\|181381	PRK08316, PRK08316, acyl-CoA synthetase; Validated.	0
NZ_CP041607.1\|WP_143600516.1\|1769072_1770215_+\|phosphotransferase	gnl\|CDD\|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	1.26612e-12
NZ_CP041607.1\|WP_097283306.1\|1792213_1794637_+\|penicillin-amidase	gnl\|CDD\|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	1.0667e-129
NZ_CP041607.1\|WP_060902539.1\|1784217_1785384_-\|thiolase-domain-containing-protein	gnl\|CDD\|181378	PRK08313, PRK08313, thiolase domain-containing protein.	0
NZ_CP041607.1\|WP_097283304.1\|1788615_1790235_+\|acyl-CoA-synthetase	gnl\|CDD\|236100	PRK07798, PRK07798, acyl-CoA synthetase; Validated.	0
NZ_CP041607.1\|WP_143600514.1\|1765825_1767256_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.14939e-38
NZ_CP041607.1\|WP_143600513.1\|1763357_1765379_-\|phospholipase-C,-phosphocholine-specific	gnl\|CDD\|274561	TIGR03396, PC_PLC, phospholipase C, phosphocholine-specific, Pseudomonas-type. Members of this protein family are bacterial, phosphatidylcholine-hydrolyzing phospholipase C enzymes, with a characteristic domain architecture as found in hemolytyic (PlcH) and nonhemolytic (PlcN) secreted enzymes of Pseudomonas aeruginosa. PlcH hydrolyzes phosphatidylcholine to diacylglycerol and phosphocholine, but unlike PlcN can also hydrolyze sphingomyelin to ceramide ((N-acylsphingosine)) and phosphocholine. Members of this family share the twin-arginine signal sequence for Sec-independent transport across the plasma membrane. PlcH is secreted as a heterodimer with a small chaperone, PlcR, encoded immediately downstream. [Cellular processes, Pathogenesis].	0
NZ_CP041607.1\|WP_054232930.1\|1783891_1784134_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.28273e-11
NZ_CP041607.1\|WP_143600512.1\|1762325_1763339_+\|inositol-2-dehydrogenase	gnl\|CDD\|275173	TIGR04380, hypothetical_protein_HOLDEFILI_04020, inositol 2-dehydrogenase. All members of the seed alignment for this model are known or predicted inositol 2-dehydrogenase sequences co-clustered with other enzymes for catabolism of myo-inositol or closely related compounds. Inositol 2-dehydrogenase catalyzes the first step in inositol catabolism. Members of this family may vary somewhat in their ranges of acceptable substrates and some may act on analogs to myo-inositol rather than myo-inositol per se. [Energy metabolism, Sugars].	3.17173e-52

>NZ_CP041607.1|WP_054232928.1|1779263_1779761_-|hypothetical-protein
MSFLRRRSATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQGVFLRYDLFGGRGPAMIIGNLPEGSPAREVAEDEIPFEVAQLLLALENDEEVTVTGTEDIPVMQGDGLLIVRRLKLSETRISCVQFDRSDNVLVTIAAWDRPITDDLYALLKPLPPELFQQG
>NZ_CP041607.1|WP_143600518.1|1778227_1779247_+|LLM-class-flavin-dependent-oxidoreductase
MPLPSHPLRKLGFLTIGLFDEADPRRGHESTLEIIELGERLGFDSAWVRHRHLQYGISSPVAVLAAASQRTSRIELGTAVIPVGWENPLRLAEDLATVDILSGGRLNPGVSVGPPMHYDQVKQALYPDTGDVEDFGYARVERLLDFVRGKSATDFSGVEGFEVFSDRVQPHAAGLGRRMWYGGGSLRSAQWAGEHGMNLLTSSVVKAEESEDFAEIQRSHIRTFRAHHPDGDRARVSQGLVVIPTDSASPEQREKYEEYALKRTPRTATPQGPARMMFAPDLVGTSEEIAERLYAHAAFREVDEVAFALPFTFGHEDYVQILTDIATRLGPALGWQPAA
>NZ_CP041607.1|WP_097283298.1|1773019_1774024_-|LuxR-family-transcriptional-regulator
MTLEAAGVTDAEESAYRILVTMSNASAREFAIRSGATTADAAGTLEALTARGLASHTDGSPRLYRATPPDVALMPRLKRNADALDQARATATALLATYRDTMRRRDAGELIEVITGADALRQHLRRIQADTQDEMLWFCKAQYVAMPSGSNEAEFDALARGVRYRVLYEKAFFDDEGAVDNVIEGVRAGEVARAVPHLPLRLAVSDRAIAICPLVPGGPHGSPEEPTAALVRDSSLLAALIALFERYWDDAIPLHVDDTGTVSGTDGTSGADSLSTTDRRLLSLLVAGVTDKAIASQLGLSRRTVQRHIQQLMTFAGAATRMQLAWQAARRDWV
>NZ_CP041607.1|WP_097283297.1|1772595_1772961_-|hypothetical-protein
MTDGSLVVESLKVGTHLKDLRIEAREIYRFRPQNVGPGQPDVWTVIEFSVSAARAAEVAEAISGALDQPGWYADLRSADETFVVFPGRVLRYARGDRTARAEARALGWTFGVPEHQLDWSE
>NZ_CP041607.1|WP_143600517.1|1770543_1772535_+|N-acetylmuramoyl-L-alanine-amidase
MRGSVTDPEATAGHRRARRTAGAVASATLLLPLLGAAPSNSTAQASSDGLQRAFAGAAAEYHVPLSVLLGVSYLQSRWDAHAGVPSASGGYGPMHLTDARTAIAEAPHHSDGTEDARGDSSRAALLPTTKVPQNSQLPARLKTLTKAARLTGLPEERLRTDAAANVAGGAALLAAAQKDLGEPLSDDAADWYGAVARFSGADDTATAATYANDVYGVIREGEERTTDAGQQVALAARPELRPDTTQLRRAGLRTVSAKSTECPTSVSCEWIPAPYSEFGNNDYGNHDLGDRPTSQSIKYIVIHDTEGTWDGVLKLVQDPTYVSWNYTLRSTDGHIAQHVKAKDVAWHAGNWYINAKSIGLEHEGFLASPDAWYTEEMYRASARLVTYLAEKYRVPLDRQHILGHDNVPGPTTSTIPGMHTDPGPYWDWQHYFTLLGHPLQRATKAKTRTSGGLVTILPNFAQNQPRYTGCVTSGEPCAAHGSSEVRLYSRPDETSPLIKDIGLRPKGDDSTIDVNDVGSRVSTGQRYAVADRNGDWTAIWYLGQKAWFKNPQGRPTAVNASGQVVTPKAGVTEIPVYGRAYPEAAAYPAGVPVQAVSPLPYKMQAGQKYAVGDKVPGEYFYAPTFDTAPHRVVIGKDMYYEIQFGHRVAFVRAADVTLTRSRT
>NZ_CP041607.1|WP_143600516.1|1769072_1770215_+|phosphotransferase
MYTASSSVSAPPRSLHPRPAAGSGPYLDPARPAAPVLGAGRTRRVPGLGTQPLSGRIDLSGPQGAQLRTAIASVHRICPEFAPVQVLRRSGRSVLLVGTTGRSTAVAKCLLDHSSIWAERIRHEIAAYRSFVRHRPPVRVPRLIAADPDNCTLVIERMPGRVAALQRHPAEAPPRADIRAALGAICRLNAWRPPAGTFDAPLDYAERISRFHELGLLTDRDMGDLQKLVHGIAHSAGRQGMGQFCHGDALLSNILLSPAGPVLVDWEHAGWYLPGYDLATLWAVLGDAPVARRQISQLAQSAGPAARDAFLVNLMLVLTREIRTYETAVQRSMHDATPAAPGPAHPGAAPSGEEQRLLLRRLHDDCQMARRAVRAAVGTR
>NZ_CP041607.1|WP_143600515.1|1767336_1768839_-|hypothetical-protein
MNGQPNTRLSDLFGLAGWSKGELARLVNKQAAAMGHPQLATDTSRVRRWIDVGEIPRDPVPRVLAALFTERLGRVVTIEDLGLVRHGRVGKRPGGGNVEHPDGVPWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSALSSAMHDWLHTDPALVADAPVVDNPLHADPAGFDRYEAAPIGSQEIEELERSVEVFRAWDAARGGGLQRKAVVGQLNEVGGMLSYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFIIAAHAAREGGDRPRAGEALSRAARQMVHLGRPDDALDLMKLAKSGSGSEMLPRTRAMLYTIEAWAQASMGKGQAMRRTLGEAEDLFVSDKGDVPPPSWMQMFDEADMHGMQALAYRTLAEHDPAAATTAQRHAKEALHLRENGRQRSQIFDWLSLASACFIADDPEQADRYARLALVSMGANSSHRTWDRLREMYRLTAEYSGYPKIHELREEIQLALPKGLLRPKRGGTTTQA
>NZ_CP041607.1|WP_143600514.1|1765825_1767256_+|SpoIIE-family-protein-phosphatase
MPSHLSADRPAAQPPPRGSVDALISQTRRLRGEMDAVRRDAPLDGTDPQGRWQRALCDLAMHQLDDLDQHLAQLRDGPPPVPAEPARAPAVPAVSAASRRGSLLSRVGSAEWNLLTDEASWSGELYDILGRDPAAPPLTLDELPSLMLDEDRPMLTAMVTDCLIDAKPIDGEFRIVRPDGGVRTVHMMGEPVLDIDGSTAAMWAVLRDVSELRRSQRTVSESRESLQLHRHHAQSERRLAVQLQEAVLPPWRGSLRFPQRGPEALDLAARHLPSSNSALIGGDWYDAMELPDGATLLSVGDLTGQGVTVASGMAMLLGALRGMAVAGTRPGQLMSWLNQLLDASVQPSLGSAVCCRYRPETRTLTWAQAGHPAPLLFRNGTGRMLAAPDGVLLGATSGAVYGQAEETLEDGDLLLLHTDGLVPGHYGEQAVQRLLDLAPRFRGARTAQDCVRTVVEEFGESEREDDACVLIARIGS
>NZ_CP041607.1|WP_143600513.1|1763357_1765379_-|phospholipase-C,-phosphocholine-specific
MTPISRRGFVGLGASVAAGAALGVGSRPAAAAGATTGTISDVRHVVVLMQENRSFDHYFGRLKGVRGFDDRSAITLSGGYSVFNQPNGAGRQYPWKLSSTPAAGGKDGETLAQCNGDLPHSWSSQHSAWNKGRLDNWVSGVGNVRSLGYLDRSDIPFHYALADNYTICDAYFCSALSATGPNRTYLWSGKVDGSSYDGGDESGLTWQNYAEALQTAGVTWKVYQNAQDNYGDNGCAYFKKFASAKAGDPLYDRGMASVPKVTGSTPDDIAAAIRADVLAGTLPQVSWVVANQAFSEHPYAPPGDGAHFVDLVYKALAADPDVFDSTVLFLNYDENDGFFDHVPPPAPPANTAGEFLNGVPYGLGFRVPMLVISPWTRGGWVSSEVFDHTSVLRFLETWTTALGKPAACPNISSWRRKVTGDLTGVFDFGNPAYGTVPLPATSVLGIATCGPLPNPVPTTNALPAQEPGTRPARALPYQPNGYLDHLEFGSGGKILAWFTMANQGTPAGRAAHLSIHPNAYRDTTPWQYTIDAGGTASDSFNIGSGFGNGKYDLTMAGPNRFLRRFKGDATQAGKSAEVSTRYATEPGTGKTALYFKMTNSSAAPVKFTITSNQYRGDGPWTYTVAAGGSAEDYFNAVAYQNGWYDFTITVDSDASWSRRFTGHIETGTASVSG
>NZ_CP041607.1|WP_143600512.1|1762325_1763339_+|inositol-2-dehydrogenase
MSELLGVAVLGAGHMGADHVRRIVRVVNGARVAAVADPDTGRAKDAVTGIDGVSVHTEVAAALDAPGVQAVLIASPGPAHEEAVLAAFDRGLPVLCEKPMVPESAGALRVVEAEARLGRRLVQVGFMRRYDAEYQRLKSLLDSRRLGRPLMLHCTHRNVSSPPGFTSAMLVNSSVSHEIDVARWLLDQELTAVTVLRPRPSAGAPEGLLDPQFVVFETAEGALVDVEVFVNSGFGYQVRCEAVCESGSARIGDEHTMVVTTAGDAREEVAQDYLVRFADAYDREVQAWVDATRQGKVTGPGAWDGYAASAVAEAGVRALESGGRVTVELAPRPDLYV
>NZ_CP041607.1|WP_143600519.1|1783021_1783636_-|CGNR-zinc-finger-domain-containing-protein
MADSIDADTRLALDLALTIRHDGQGGVADDLAEPGGLTTWVRGHADLLPGADAFVADAAALAAVRELRAAVRALFARAVRPGDPSPADAARLLPVPQAVLCLNTAAALAPTVPVLTWDDGAEPVVRRQAVGGAAPLPALLARAALAFLASPDRSRLHACHAPRCVRYFIKEHPRQEWCKPSCGNRARVARHHERHRKSAQAVGD
>NZ_CP041607.1|WP_054232930.1|1783891_1784134_-|DUF397-domain-containing-protein
MAESTIEQHPLAGWDKPELDLSNAEWQSSSRGRGDVQIAFVEGFIAMRNSGRPASPSLIFTPAEWGAFVSGAREGEFDLT
>NZ_CP041607.1|WP_060902539.1|1784217_1785384_-|thiolase-domain-containing-protein
MSKEPVAVVGIGQTKHVAARRDVSLAGLVREAAGRALADAELTWADIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVATNLIAGRVHGTVLTLAYEKQSESNAMWGLSLPIPFQQPLLAGAGGFFAPHVRAYMRRTGAPDTVGSLVAYKDRRNALKNPYAHLHEHDITLEKVQASPMLWDPIRYSETCPSSDGACAMVLTDRAGAARAPRPPAWLHGGAMRSEPTLFAGKDCVSPQAGKDCAADVYRQAGIADPRRDIDAVEMYVPFSWYEPMWLENLGFAEEGEGWKLTESGVTELDGDLPVNMSGGVLSTNPIGASGMIRFAEAALQVRGQAGEHQVEGARRVLGHAYGGGSQFFSMWLVGAEPPTS
>NZ_CP041607.1|WP_054232932.1|1785380_1786436_-|lipid-transfer-protein
MPPIRDVAVVAFAQSDHLRTTDELSEVEMLIPVLHAVLDQTGLKTSDIGFTCSGSSDYLAGRAFSFTMALDGVGAWPPISESHVEMDGAWALYEAWTKLLTGDADTALVYGYGKSSPGSVRDVLTRQLDPYYVAPLWPDSVALAALQAQALIDAGETDEPALAGVASRSRASAATNSHAQLRGSVAQGEYLVRPLRVGDCPPVGDGGAAVILAAGERARELCERPAWIRGIDHRIEAHGLGVRDLTDSPSTRLAAERAGAFERPVDTAELHAPFTSQEVVLRKALRLGQEVRVNPSGGALAANPIMAAGLIRIGEAAARVHRGESDRALAHATSGPCLQQNLVAVLEGDPR
>NZ_CP041607.1|WP_054232933.1|1786436_1787378_-|DNA-binding-protein
MPEVLKAPLVVEFPFTRSLGPVQSAFLTGLRERVVLGVKTADGRTLVPPVEYDPVTAEDLGELVEVAPTGTVTTWAWNHEPRRGQPLDTPFAWVLVRLDGADTALLHALDAPGPEAVRTGMRVRVRWAAQRTGAITDIACFEPYDGDRPQLAGHDGRFEDMVTGIVAPARLDYVYSPGRAQSAYINSLSSRRTVGERCPSCRKVYVPPRGACPTCGVVTSEQVEVGPRGTVTTYCIVNIKARNLDIEVPYVYAHIALDGADLALHGRIGGIPYDQVRMGLRVEPVWTEGGRYPDHYRPTGEPDAEYDTYKELL
>NZ_CP041607.1|WP_060902537.1|1787627_1788428_-|crotonase/enoyl-CoA-hydratase-family-protein
MGGTEHLTVQREGATLVLTLNRPEAKNALSLPMLVGLYDGWIEADEDDAIRSIVLTGAGDAFCAGMDLKALAGRGMEGQQYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGHCVAGGTEILQGTDIRVAAESATFGLFEVKRGLFPIGGSTVRLQRQIPRTHALEMLLTGRPYSAREAAGIGLVGHVVPDGTARQKALEIAELINACGPLAVEAVKASVYETAEMTETEGLAAELTRGWPIFDTADAKEGSRAFTEKRPPVYRRA
>NZ_CP041607.1|WP_097283304.1|1788615_1790235_+|acyl-CoA-synthetase
MEYNLADLFESVVDVVPGREALVYIDHPGTGAERRLTYAQLDAAANRVAHHLIDSGIRPGEHLGLHLYNGVEYVQTVLGCLKARIVPVNVNYRYVEEELVYLYRDADLVALVFDTEFTDRVAAALPRASALRHLLRVGDAAADAASLPALDFAEAEAAGSPERGFPPRSADDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVTKPEELAERVAAGGEGITFFPTPPLMHGTSTLTAFIGFNFGQRVVIHRKFVPEEVLRTVEREKVTSMSLVGDAMLRPLIDALRGPMKGTDCSSMFSVSSSGAIMSETVREQFQSLVPNVMLLNNYGSSESGFNGTATADSGAGQGFRLRVNSRTQVVDPATYEPVAVGEPGRVAQRGHVPLGYYNDPKKTAETFFQKDGERWVLLGDMATVDEEGIVTVLGRGSQCINTGGEKVYPEEVEQALKSHPDVYDALVAGVPDEKWGNHVAAVVQLREGAGSPSLEDIQTHCRSHLAGYKIPRQLVITDTIQRSPSGKADYRWARSVATQAAH
>NZ_CP041607.1|WP_143600520.1|1790483_1792028_-|AMP-binding-protein
MTAGQNPTVAAGRSATVDGVLRRSARRTPERVAIHYRDRSWTYAELDEAVSRAAQVLRSSGLAPGDRVGAYGHNSDAYLIGFLACARGGLVHVPVNQNLTGDDLAYIVGQAGCGLVLADPDLAGNLPEGTRVLALRDSDDSLLARLDTTTPYDGPEPRGEDLTQLLYTSGTTAQPKGAMLTHRALVHEYLSAITALDLQAGDLPVHSLPLYHSAQMHVFLLPYLAVGAVNVILDAPDAGQILDLVEAGHADSLFAPPTVWIGLSQRPDFATRDLSGLRKAYYGASIMPVPVLERLRERLPKLAFYNCFGQSEIGPLAMVLGPHEHKGRMDSCGRPVLFVEARVVDESGKDVPDGERGEIVYRSPQLCEGYWDKPEETAEAFRDGWFHSGDLAVRDEEGYFTVVDRVKDVINSGGVLVASRQVEDALYTHDAVAEVAVVGLPDERWIEAVTAVVVARTEVTEAELLAHAREKLAAFKAPKRVIFVDELPRNASGKILKRELRDRFADARAESAQG
>NZ_CP041607.1|WP_097283306.1|1792213_1794637_+|penicillin-amidase
MRIRPGRFAVLAVALLTASAALPATAANGQERQHSPSHPSSGGLSAVIRYTEYGIPHILAKNYPDLGFGTGWAQAADQVCTLADGFVTLRGERSRFFGPDAAPDGSLSSAAENLSSDLYFRGVRATGTVEKLLAEPAPRGPSRDSKDLMRGWAAGYNAWLAQNRITDPACRGASWVRPVTAVDVAARTFALAVLGGQGRAVDGITAARPPATTAARTAVGIPDAQSAARAARRLFDTADMGSNAVAFSGATTANGRGLLLGNPHYPWQGGRRFWQSQQTIPGELNVAGGALLGSTTVSIGHNARMAWSHTVATGVTLNLHQLTLDPADPTTYLVDGKPERMTRRTVTVEARGGPPVTRTQWWTRYGPVVTSLGAGLPLPWTSTTAYALNDPNAENLRAPDTALGFGRARGTADVLTTLRRTQGLPWINTIAADSGGHSLFTQSQVLPRITDELAQRCSTALGKALYPSSGIAVLDGSRGDCAPGSDPDAVQPGIFGPAHMPVLKDAPYAENSNDSAWLANTDRPLTGYERVFGPIGSPLSSRARGAKADVSAMAAKGELTVRDLQAQQFANRATSGDLIADDSARACAALPGGTATGSDGKAVDVSEACGVLKAWDHSMKTGSRGALLFDRFWRRLTAVTAPAQLWKVPFSAADPVHTPNTLNTRAPGVATALADAVSELRAAGIALDATLGAHQVVVRGDRRIPVPGGTESLGVWNKVEPVWDAAAGGYTEVTTGSSYIQAVGWDGGRCPVARTLLTYSQSSNPNSPHFSDQTRLFSEGKWVTSRFCEKDILSSPGLRVIRVGEHR
>NZ_CP041607.1|WP_143600521.1|1794700_1796251_-|AMP-binding-protein
MSTAPNGFWAQATADPGRTVLITPDGDEWTAGRLHAAANRLVHGLRAAGLERGDAFAVVLPNGVECFVAYLAASQAGLYLVPVNHHLVGPEIAWIVSDSGAKVLIAHERFADAARHAADEAKLPAAQRYAVGTVAGFRPYAELLDAQPDSAPADRTLGWVMNYTSGTTGRPRGIRRPLPGKLPEESYLGGFLGIFGIRPFDDNVHLVCSPLYHTAVLQFAGASLHIGHRLVLMDKWTPEEMLRVIDAHACTHTHMVPTQFHRLLALPDEVKARYDVSSMRHAIHGAAPCPDHVKRAMIEWWGHSVEEYYAASEGGGAFATTEDWLKKPGTVGKAWPISELAVFDDDGNRLPPGELGTVYMKMSTGGFSYHKDESKTKKNRIGDFFTVGDLGCLDEDGYLFLRDRKIDMIISGGVNIYPAEIEAALLSHPAVADAAAFGIPHDDWGEEVKAVVEPAPGHEGGPALAADILGHCERLLAGYKRPKSVDFIESMPRDPNGKLYKRRLRDPYWEGRTRAM

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Crispr_ID: NZ_CP041607_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_5

3155229-3155364

Orphan

Consensus_repeat	Method
GGTGGGGGCTTGGCGCGCAGTTCCCCGCGCCCCTGGGGGCGGGGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_5

>merge|NZ_CP041607|5|3155229-3155364|CRISPRCasFinder
GGTGGGGGCTTGGCGCGCAGTTCCCCGCGCCCCTGGGGGCGGGGCTCCGCCCCGCATCCCCGGCCGTGCCAAGTTCGTCGGCTGACGGCCGGTGGGGGCTGGGCGCGCAGTTCCCCGCGCCCCTGGGGGCGGGGCT

>NZ_CP041607|5|4|3155229-3155364|CRISPRCasFinder
GGTGGGGGCTTGGCGCGCAGTTCCCCGCGCCCCTGGGGGCGGGGCT	CCGCCCCGCATCCCCGGCCGTGCCAAGTTCGTCGGCTGACGGCC
GGTGGGGGCTGGGCGCGCAGTTCCCCGCGCCCCTGGGGGCGGGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_054230570.1\|3153000_3153435_-\|NfeD-family-protein	unknown	unknown	gnl\|CDD\|224501
NZ_CP041607.1\|WP_054232214.1\|3155454_3155700_-\|chaplin	unknown	unknown	gnl\|CDD\|367652
NZ_CP041607.1\|WP_143601245.1\|3166732_3167251_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NZ_CP041607.1\|WP_143605346.1\|3140649_3141441_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|367841
NZ_CP041607.1\|WP_143601242.1\|3159949_3160723_+\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381605
NZ_CP041607.1\|WP_054230569.1\|3151933_3152869_-\|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl\|CDD\|223407
NZ_CP041607.1\|WP_143601243.1\|3163554_3165315_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NZ_CP041607.1\|WP_054230566.1\|3149829_3150615_+\|sporulation-protein	unknown	unknown	gnl\|CDD\|369195
NZ_CP041607.1\|WP_143601238.1\|3148388_3148730_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_097284100.1\|3150654_3151188_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|182339
NZ_CP041607.1\|WP_143601239.1\|3156493_3157663_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|226951
NZ_CP041607.1\|WP_054232215.1\|3155859_3156501_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP041607.1\|WP_143601240.1\|3157851_3158547_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187625
NZ_CP041607.1\|WP_054230572.1\|3153508_3154300_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP041607.1\|WP_054230568.1\|3151346_3151853_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|224321
NZ_CP041607.1\|WP_097284099.1\|3148951_3149593_-\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|376746
NZ_CP041607.1\|WP_143605347.1\|3160807_3163312_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP041607.1\|WP_143601244.1\|3165426_3166638_+\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_CP041607.1\|WP_143601241.1\|3158543_3159650_+\|S-adenosylmethionine:tRNA-ribosyltransferase-isomerase	unknown	unknown	gnl\|CDD\|376813
NZ_CP041607.1\|WP_054230571.1\|3154421_3155210_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_054230570.1\|3153000_3153435_-\|NfeD-family-protein	gnl\|CDD\|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	5.05993e-17
NZ_CP041607.1\|WP_054232214.1\|3155454_3155700_-\|chaplin	gnl\|CDD\|367652	pfam03777, DUF320, Small secreted domain (DUF320). Small domain found in a family of secreted streptomyces proteins. It occurs singly or as a pair. Many of the domains have two cysteines that may form a disulphide bridge.	7.27134e-16
NZ_CP041607.1\|WP_143601245.1\|3166732_3167251_-\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	3.54943e-39
NZ_CP041607.1\|WP_143605346.1\|3140649_3141441_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|367841	pfam04147, Nop14, Nop14-like family. Emg1 and Nop14 are novel proteins whose interaction is required for the maturation of the 18S rRNA and for 40S ribosome production.	3.95789e-06
NZ_CP041607.1\|WP_143601242.1\|3159949_3160723_+\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381605	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains. These tail fiber-like proteins are multi-domain proteins that include a lytic transglycosylase (LT) domain. Members of the LT family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, and the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL). LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.72445e-31
NZ_CP041607.1\|WP_054230569.1\|3151933_3152869_-\|SPFH/Band-7/PHB-domain-protein	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	2.56918e-67
NZ_CP041607.1\|WP_143601243.1\|3163554_3165315_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	1.07714e-05
NZ_CP041607.1\|WP_054230566.1\|3149829_3150615_+\|sporulation-protein	gnl\|CDD\|369195	pfam07070, Spo0M, SpoOM protein. This family consists of several bacterial SpoOM proteins which are thought to control sporulation in Bacillus subtilis.Spo0M exerts certain negative effects on sporulation and its gene expression is controlled by sigmaH.	6.301e-107
NZ_CP041607.1\|WP_097284100.1\|3150654_3151188_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	4.35128e-61
NZ_CP041607.1\|WP_143601239.1\|3156493_3157663_-\|GAF-domain-containing-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.10535e-50
NZ_CP041607.1\|WP_054232215.1\|3155859_3156501_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.23812e-81
NZ_CP041607.1\|WP_143601240.1\|3157851_3158547_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187625	cd05367, SPR-like_SDR_c, sepiapterin reductase (SPR)-like, classical (c) SDRs. Human SPR, a member of the SDR family, catalyzes the NADP-dependent reduction of sepiaptern to 7,8-dihydrobiopterin (BH2). In addition to SPRs, this subgroup also contains Bacillus cereus yueD, a benzil reductase, which catalyzes the stereospecific reduction of benzil to (S)-benzoin. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.24012e-41
NZ_CP041607.1\|WP_054230572.1\|3153508_3154300_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	3.30392e-93
NZ_CP041607.1\|WP_097284099.1\|3148951_3149593_-\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|376746	pfam02245, Pur_DNA_glyco, Methylpurine-DNA glycosylase (MPG). Methylpurine-DNA glycosylase is a base excision-repair protein. It is responsible for the hydrolysis of the deoxyribose N-glycosidic bond, excising 3-methyladenine and 3-methylguanine from damaged DNA.	5.56048e-90
NZ_CP041607.1\|WP_143605347.1\|3160807_3163312_-\|FHA-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.85208e-74
NZ_CP041607.1\|WP_143601244.1\|3165426_3166638_+\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.72779e-93
NZ_CP041607.1\|WP_143601241.1\|3158543_3159650_+\|S-adenosylmethionine:tRNA-ribosyltransferase-isomerase	gnl\|CDD\|376813	pfam02547, Queuosine_synth, Queuosine biosynthesis protein. Queuosine (Q) biosynthesis protein, or S-adenosylmethionine:tRNA -ribosyltransferase-isomerase, is required for the synthesis of the queuosine precursor (oQ). It catalyzes the transfer and isomerisation of the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to form epoxyqueuosine (oQ-tRNA). Q is a hypermodified nucleoside usually found at the first position of the anticodon of asparagine, aspartate, histidine, and tyrosine tRNAs. In Streptococcus gordonii, QueA has been shown to play a role in the regulation of arginine deiminase genes.	7.97901e-65
NZ_CP041607.1\|WP_054230568.1\|3151346_3151853_+\|HNH-endonuclease	gnl\|CDD\|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	1.16282e-17

>NZ_CP041607.1|WP_054230571.1|3154421_3155210_+|hypothetical-protein
MLSEPRSGRLAAWGNALLAGLVSPDDAALAIVGEDAVHRVEGLPGESGPVGLTLALGRLRALGVKGLRVALPAPGHPLGLSGPPDFNARALDAEEAVVCHGAALGLVPEVYEAGPEGDVHVEVVWHCLAVREAPPADVPSLGEAERELAEALREATEVLSRLDVAGSGPVAEAAVDAYRARAERGREVLAPGYPPRAVRVLELAQRVGLLISVAYENGHGGAVSASEISARALALRPVERTARRAQVAAYNAFVEERERGVR
>NZ_CP041607.1|WP_054230572.1|3153508_3154300_-|ABC-transporter-ATP-binding-protein
MSDVLELEDVSVVREGRALVDQVSWSVKEGERWVILGPNGAGKTTLLNLASSYLFPSQGTATILGETLGKVDVFELRPRIGVAGIAMAEKLPKRQTVLQTVLTAAYGMTAGWHEDYEDIDEQRARAFLDRLGMSDYLDRRFGTLSEGERKRTLIARALMTDPELLLLDEPAAGLDLGGREDLVRRLGRLARDPIAPSMIMVTHHVEEIAPGFTHVLMIRQGKVLAAGPLELELTSRNLSLCFGLPLIVEQNGERWTAQGLPMS
>NZ_CP041607.1|WP_054230570.1|3153000_3153435_-|NfeD-family-protein
MNDINAWVWWLVGAAALGIPLVVTAMPEFGMLALGAAAAAVTAGLGGDVVLQVLVFAVVSFALIAVVRPVAARHRAQRPQLATGVEALKGKQAIVLERVDGSGDGRIKLGGEIWSARALDAQQAYEVGQEVDVVDIEGATAIVM
>NZ_CP041607.1|WP_054230569.1|3151933_3152869_-|SPFH/Band-7/PHB-domain-protein
MAPIIIVLIILVVLVFIALIKTIQVIPQASAAIVERFGRYTRTLNAGLNIVVPFIDSIRNRIDLREQVVPFPPQPVITQDNLVVNIDTVIYYQVTDARAATYEVASYIQAIEQLTVTTLRNIIGGMDLERTLTSREEINAALRGVLDEATGKWGIRVNRVELKAIEPPTSIQDSMEKQMRADRDKRAAILTAEGIRQSQILTAEGEKQSAILRAEGEAKAAALRAEGEAQAIRTVFESIHAGDADQKLLAYQYLQMLPKIAEGDANKLWIVPSEIGDALKGLSGAMGNFGPMGGGSGNAGTERREKPSVTD
>NZ_CP041607.1|WP_054230568.1|3151346_3151853_+|HNH-endonuclease
MRDTLVLNASFEPLSTVTLNRAVVLVLQDKAVVEQAHPELRMRGAALDIPVPRVIRLCRYVRVPFRRQAPWSRRGVLIRDRHRCAYCGRRATTVDHVVPRAQGGRDSWLNTVASCAEDNHRKADRTPEQAGMPLLRQPFEPTPADAMLLALGRDDLDALPEWLAQPAA
>NZ_CP041607.1|WP_097284100.1|3150654_3151188_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MTELKRPPLPHDFHPPVPAFTVTSEDVEPGGVLKDAQVYAAGNTSPQLSWEGFPPETKSFAVTCFDPDAPTGSGFWHWVVFDIPASVTELPTGAGSGKFEGLPEGAVQVRNDYGSKDFGGAAPPAGDPAHRYVFTVYAVDQEKLGPDAEVSPAVVGFNLRFHSLARAQLMGEYASPA
>NZ_CP041607.1|WP_054230566.1|3149829_3150615_+|sporulation-protein
MGFKRLLASLGAGGASVETVLTEVNVVPGGVVQGEVRIQGGSVNQAIEGLSVGLQAKVEVEGHDDQEYKQDIEFTKLRLGGAFELQAGAVHAVPFGLEIPWETPITTIDGQALRGMHIGVTTELEIARAVDSGDLDPINVHPLPAQQAILNAFIQLGFRFKNADMERGHIRGTRQKLPFYQEIEFFPPSQYRGLNQVELSFVADDHEMDVILEMDKKPGLFSEGSDSYRSFRVGLHDYQGTDWAAYLNQWLSEVGSKRSWF
>NZ_CP041607.1|WP_097284099.1|3148951_3149593_-|DNA-3-methyladenine-glycosylase
MIAAPDRTPITRDFFDRPVLEVAPDLLGRVLVRTTPDGPIELRLTEVEAYDGPNDPGSHAYRGRTARNDVMFGPPGHVYVYFTYGMWFCMNLVCGPEGNPSGVLLRAGEIIEGAELARKRRLSARNDKELAKGPARLATALGVDRALDGADACGPEGSPLTLLTGTPVRSDQVRNGPRTGVAGDGGVHPWRFWVANDPTVSPYRAHTPRRRST
>NZ_CP041607.1|WP_143601238.1|3148388_3148730_+|hypothetical-protein
MPGRTFSKEPRPSRSAGDGVSTYLALIFGTLLSSQGTDASFVLTLSGFPPGASLRSCCPALFLRFRLYQTVSRSDFLGAFQVSAFAFPFPAVPTVSDSFVSDSLSERDSVLRL
>NZ_CP041607.1|WP_143605346.1|3140649_3141441_-|tetratricopeptide-repeat-protein
MVARLIDEDPEGAYAYSKIALRLASRVAAVREAAGFAAYANQKYSEALAEFRAARRMTGNVDLWPVMADCERGLGRPEKALDMAGAPEVHKLDKAGQVEMRLVAAGARRDIGQLDAAIVTLQSPELASNSVQPWTARLRYAYADALLAAGREDEAREWFAKAVESDKDGSTDASDRLAELDGVEFVDALVEDEDEDEVAPEAEAEDEAEDESETATDAEADTDPDTEVETEVDDEDDDKDDIVEAERTKPVVEADDDDEAPRG
>NZ_CP041607.1|WP_054232214.1|3155454_3155700_-|chaplin
MKNLKKATAVAMVAGGLVAAGAGMASATDGSWAGGNAAGSPGVVSGNVIQAPIHIPVNAVGNSVNVIGVLNPAFGNLGLNH
>NZ_CP041607.1|WP_054232215.1|3155859_3156501_-|response-regulator-transcription-factor
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVARAEELKPDVVLMDVKMPGMDGIDALRKLRELANPARVLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGVLLSQEEANSGQGRGGSLTEREREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG
>NZ_CP041607.1|WP_143601239.1|3156493_3157663_-|GAF-domain-containing-protein
MSQGPRSGLYAVSSALLAMSRHLEVRDVLKTIVASARELLDAQYAALGVPDDHGGFAQFVVDGVSDAQWKAIGPLPRQHGILAAMLHEARPERLADVRKDPRFEGWPAAHPDMSDFLGLPIRDGDEVIGALFLANKNRTKENQKDCSAPDGGCGFTEDDQELLTILAQHAAIALTNARLYERSRELTIAEERSRLAHELHDAVSQKLFSLRLTAQAAAALVDRDPARAKGELHQVAMLAAEATEELRAAVIELRPAALDEDGLVATLRTQIQVLDRAHSARVTFAGNGVRALPAAQEEAMLRVAQEALHNALRHSGAGRVDVTLEKRGTGTVLRVSDDGSGFEPTAVRAAGRHLGLVSMRDRSSGVGGTLSVESAPGKGTTIEMEVPGG
>NZ_CP041607.1|WP_143601240.1|3157851_3158547_+|SDR-family-NAD(P)-dependent-oxidoreductase
MPVAIITGASKGLGRALATALAERGWDLVLDARTAGVLKETAEALSAYGTRVEALPGDVGDAGHRAGLVAAARGLGGVDLLVNNASALGAEPLVRLEDLPLDGLRHALEVNVVAALGLVQEALPLLRAAPAGAVVAVSSDAAAEAYETWGGYGASKAALDHLAAVLGVEEPGLRVWAVDPGDMGTDLYAAAVPDDGDARPTPDSVVPAFLRLLDERPASGRYGAPALLEVR
>NZ_CP041607.1|WP_143601241.1|3158543_3159650_+|S-adenosylmethionine:tRNA-ribosyltransferase-isomerase
MTTTVRVPEERSARVPAEQRGPGRDRDSVRLLVSCGTEVSHHAFVELPRRLRAGDLLIVNTSPTLAAAVDGWIGHARVVVHFSTRGDDGRWAVELRDPDGRGTTRARAGGPAGTKVRLAGDVRLVLEEPLTPYGSTLTPYGSRLWWGRVSEPDVLGLLRRHGRPIRYSYTQRDQPLSVYQTVFALPSADGGGSAEMPSAARPFTARLVAELVSRGVQFAPITLHTGVASAEAHEPPYPERYEVPEASARLINAARAGEGRILAVGTTAVRAVESAVDAGGVVRARKGWTDLVVTPERGVRVVDGLLTGLHEPEASHLLMLEAIAGRAAIERSYGEALSGLYLWHEFGDVHLILPEEGPHTEGCSSNCR
>NZ_CP041607.1|WP_143601242.1|3159949_3160723_+|transglycosylase-SLT-domain-containing-protein
MTKNTRTPGHSPKLTKLHKLSIAGVATLGAATLAFSLAPNHTQATTNDAAISAAPVAFSQQPIKNVQARVTDQQAGASLKTQAIEAKKKAADAAAATKAAENVRKVQAASRSVQRPAIETIAMKTVAMKTATTKTYATKTATTKAATTKTYANNLDGWIRQSLDIMKRRGIPGSYNGLHRNIMRESSGNPMAINGWDINAINGIPSKGLLQVIQPTFNAYHVPGTSWNIYDPVANITAAANYAADKYGSMDNVNSAY
>NZ_CP041607.1|WP_143605347.1|3160807_3163312_-|FHA-domain-containing-protein
MPELVLELNGRTWTLDASRPYTLGRDPQGDVVLDDARVSWRHATMSWDGRSWVIEDHGSTNGTFVQGQRIHRMEIGPGSAVHLGNATDGPRLNLSGAAAAVAQPQQQPYAAQGASPGWAQQTPPQQTPEQSHQQPQQPAARVPQQQGPGGGAGAPPVYGDRSPTTFHQLDLGRVMRIGRALENELVVSDLQVSRHHAEFHATPGGRFEIRDLGSHNGTYVNGQPIAKGGSALLGPNDIVGVGHSTFRLVGDRLEEFVDTGEVSFSARHLTVTVDGGKQILKDVSFGVPEKSLIAVIGPSGSGKSTLLKALTGYRPANQGDVLYDNRNLYKQFAELRQRIGLVPQDDILHKELTVKKALKYAAKLRFPADTTTAEREARIDEVLRELKLDIHKEKKVTSLSGGQRKRVSVALELLTKPSLIFLDEPTSGLDPGMDRDVMQLLRGLADDGRTVLVVTHSVAELAICDKLLVMAPGGSVAYFGPPEEALNFFGYETWADVFSAFENYRDYDWAGRWKGSQHYQMYAADIDAVAPQSANVTPPQAMKPPKPQGWFSQLSTLVRRYVSVIVSDKGFLALTVILPAVLGAVSLLIDPNKTLLVNAQVNPKTGVHVPNGTATTVLLILAVGACFAGAANSVRELIKERVIYERERATGLSRSAYLMSKVVVLGVVTVLQGAMVGAIGFTSRTKPTEGVVFGHSVLLELSIPIMALGFTSMMFGLVISSLVKTAEKTMPLLVMFAIIQVVFTGCLFILNGKIGVNEFSYLMPSRWAVAAAGATLDFNNINPNTDDPSSTDPLWNHTATAYGMDIVALLVLAAVCGFFVARFLRRHEPEVMRK
>NZ_CP041607.1|WP_143601243.1|3163554_3165315_+|hypothetical-protein
MSIDTARHGGRLPWGDVLLSAIASVSWALIAMAGTAALGLHLVGADAAGSLGPMTAAVVALGANGAVKPSGDVSAFGLKGAEAHTAIQITPLGVGLVGALLLSFFFLRSLRGAGVVIAPSELLARAGAVVVLFVATLGGLAWAGHDIITIDGSKLGLDRVTGGGGLGNITDKLPGGLGDLGGLLPGKIGDLVQAQAAVGFTVDTVPTLLGGAAWAAGILVIALLASRRTPLPRGWEGVHRMVRPAASALVTVVLVAVLAGLAAAAYAAIGDPHPKLIAGAALLGAPNGVWLGIPIGLFVPWDGKATGELAKLLPHPLDRLLSVDSYQPVTLGRLAELDGRVWLLGVATAVMMLFAGVLAASRTPFVRERGAASVGTPAAPVVGGGGALGFAGRCALRLGIVTALALPLLAWLTDVSVDASLSVFGIDAFGAGIRLHGHLGMALLLGAVWGAGAGAAGALLAYASGAAGRRAAPLALGDAGPPVAAPAPDLPRGPGPYAPGAPYRPANPDTNPYLRLPDELREPDDGWPAERPRSPDDVYGAPTVVRPMAPPPGPQKRRPRGRDVPPPPQPPPGQGPSAPPGPGRQS
>NZ_CP041607.1|WP_143601244.1|3165426_3166638_+|phosphoserine-phosphatase-SerB
MSASQTSEVPTLLVKIFGKDRPGITAGLFDTLAAYSVEVVDIEQVVTRGRIVLCALVTEPPAGLEGDLRATVHSWAESMKMQAEIISGLGDNRPRGLGRSLVTVLGHPLTAESTAAIAARITKTGGNIDRIFRLAKYPVTAVEFAVSGTGTEALRTALVTEAAALGVDIAVVAAGLHRRAQRLVVMDVDSTLIQDEVIELFAAHAGCEEQVAEVTAAAMRGELDFEQSLHARVALLKGLDASVVAKVREEVRLTPGARTLIRTLKRLGFQVGVVSGGFTQVTDDLKERLGLDFAQANTLEIVDGKLTGRVTGEIVDRAGKARLLRRFAAEAGVPLAQTVAIGDGANDLDMLNAAGLGVAFNAKPVVRQAAHTAVNFPFLDTVLYLLGVTREEVEAADMHLGDH
>NZ_CP041607.1|WP_143601245.1|3166732_3167251_-|histidine-phosphatase-family-protein
MSVAEPRRIVLFRHAKADWPQVSDHERPLADRGRKDAAVAGRKLADTGIPFDMALCSTATRTRETWKLAVHELPHRPKTVYEERLYEASPGELIAVLNETPDDAHNVVLIGHNPGIQGLTEVLAGQAEGDTRTRMAAHGFHTGAFAVLSVEGSWKSLEPGVCTLTDYWAPTE

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Crispr_ID: NZ_CP041607_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_6

3460880-3460996

Orphan

Consensus_repeat	Method
CCTCCGGCCCCTTCCTCACACCCGACGGACTGAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_6

>merge|NZ_CP041607|6|3460880-3460996|CRISPRCasFinder
CCTCCGGCCCCTTCCTCACACCCGACGGACTGAAAGGCGCGAGCCAGGGTGGGTGGGGTGACGGGGCGGGTGGGGCATCGGCCTCCGGCCCCTTCCGCACACCCGACGGACTGAAAG

>NZ_CP041607|6|5|3460880-3460996|CRISPRCasFinder
CCTCCGGCCCCTTCCTCACACCCGACGGACTGAAAG	GCGCGAGCCAGGGTGGGTGGGGTGACGGGGCGGGTGGGGCATCGG
CCTCCGGCCCCTTCCGCACACCCGACGGACTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143601345.1\|3459189_3460554_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|99743
NZ_CP041607.1\|WP_054236003.1\|3469593_3470490_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054236004.1\|3470586_3471630_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293786
NZ_CP041607.1\|WP_143601342.1\|3449366_3450350_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223488
NZ_CP041607.1\|WP_054235994.1\|3453394_3454831_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|180487
NZ_CP041607.1\|WP_097284255.1\|3468580_3469441_-\|serine-protease	unknown	unknown	gnl\|CDD\|238113
NZ_CP041607.1\|WP_097288885.1\|3464895_3465264_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|181719
NZ_CP041607.1\|WP_143601343.1\|3452608_3453385_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379154
NZ_CP041607.1\|WP_143601347.1\|3465275_3466160_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP041607.1\|WP_097284250.1\|3455833_3457648_+\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|236506
NZ_CP041607.1\|WP_143601348.1\|3466269_3468039_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|366567
NZ_CP041607.1\|WP_143601349.1\|3471697_3472615_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|236099
NZ_CP041607.1\|WP_143605358.1\|3472611_3473382_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|236116
NZ_CP041607.1\|WP_054235991.1\|3451171_3451555_-\|DUF2267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378360
NZ_CP041607.1\|WP_143605357.1\|3461519_3464018_-\|aminopeptidase-N	unknown	unknown	gnl\|CDD\|274121
NZ_CP041607.1\|WP_143601344.1\|3457771_3459193_-\|SidA/IucD/PvdA-family-monooxygenase	unknown	unknown	gnl\|CDD\|226017
NZ_CP041607.1\|WP_054235992.1\|3451677_3452328_-\|response-regulator	unknown	unknown	gnl\|CDD\|226230
NZ_CP041607.1\|WP_143601346.1\|3464100_3464691_-\|response-regulator	unknown	unknown	gnl\|CDD\|381085
NZ_CP041607.1\|WP_060898114.1\|3454981_3455695_-\|DUF541-domain-containing-protein	unknown	unknown	gnl\|CDD\|377344
NZ_CP041607.1\|WP_060898117.1\|3450346_3451063_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223487

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143601345.1\|3459189_3460554_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|99743	cd06450, DOPA_deC_like, DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.	3.63943e-78
NZ_CP041607.1\|WP_054236004.1\|3470586_3471630_+\|hypothetical-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	3.43126e-20
NZ_CP041607.1\|WP_143601342.1\|3449366_3450350_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223488	COG0411, LivG, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	5.64466e-121
NZ_CP041607.1\|WP_054235994.1\|3453394_3454831_-\|pyruvate-kinase	gnl\|CDD\|180487	PRK06247, PRK06247, pyruvate kinase; Provisional.	0
NZ_CP041607.1\|WP_097284255.1\|3468580_3469441_-\|serine-protease	gnl\|CDD\|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	8.80264e-67
NZ_CP041607.1\|WP_097288885.1\|3464895_3465264_-\|chorismate-mutase	gnl\|CDD\|181719	PRK09239, PRK09239, chorismate mutase; Provisional.	2.49536e-55
NZ_CP041607.1\|WP_143601343.1\|3452608_3453385_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379154	pfam13384, HTH_23, Homeodomain-like domain.	0.00906441
NZ_CP041607.1\|WP_143601347.1\|3465275_3466160_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.70943e-23
NZ_CP041607.1\|WP_097284250.1\|3455833_3457648_+\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|236506	PRK09420, cpdB, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase.	1.55115e-133
NZ_CP041607.1\|WP_143601348.1\|3466269_3468039_+\|beta-galactosidase	gnl\|CDD\|366567	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.	3.6326e-132
NZ_CP041607.1\|WP_143601349.1\|3471697_3472615_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|236099	PRK07791, PRK07791, short chain dehydrogenase; Provisional.	4.49977e-162
NZ_CP041607.1\|WP_143605358.1\|3472611_3473382_-\|SDR-family-oxidoreductase	gnl\|CDD\|236116	PRK07856, PRK07856, SDR family oxidoreductase.	9.50548e-122
NZ_CP041607.1\|WP_054235991.1\|3451171_3451555_-\|DUF2267-domain-containing-protein	gnl\|CDD\|378360	pfam10025, DUF2267, Uncharacterized conserved protein (DUF2267). This domain, found in various hypothetical bacterial proteins, has no known function.	7.82993e-25
NZ_CP041607.1\|WP_143605357.1\|3461519_3464018_-\|aminopeptidase-N	gnl\|CDD\|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP041607.1\|WP_143601344.1\|3457771_3459193_-\|SidA/IucD/PvdA-family-monooxygenase	gnl\|CDD\|226017	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	1.82009e-159
NZ_CP041607.1\|WP_054235992.1\|3451677_3452328_-\|response-regulator	gnl\|CDD\|226230	COG3707, AmiR, Response regulator with putative antiterminator output domain [Signal transduction mechanisms].	6.90874e-62
NZ_CP041607.1\|WP_143601346.1\|3464100_3464691_-\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	3.94845e-24
NZ_CP041607.1\|WP_060898114.1\|3454981_3455695_-\|DUF541-domain-containing-protein	gnl\|CDD\|377344	pfam04402, SIMPL, Protein of unknown function (DUF541). Members of this family have so far been found in bacteria and mouse SwissProt or TrEMBL entries. However possible family members have also been identified in translated rat (Genbank:AW144450) and human (Genbank:AI478629) ESTs. A mouse family member has been named SIMPL (signalling molecule that associates with mouse pelle-like kinase). SIMPL appears to facilitate and/or regulate complex formation between IRAK/mPLK (IL-1 receptor-associated kinase) and IKK (inhibitor of kappa-B kinase) containing complexes, and thus regulate NF-kappa-B activity. Separate experiments demonstrate that a mouse family member (named LaXp180) binds the Listeria monocytogenes surface protein ActA, which is a virulence factor that induces actin polymerization. It may also bind stathmin, a protein involved in signal transduction and in the regulation of microtubule dynamics. In bacteria its function is unknown, but it is thought to be located in the periplasm or outer membrane.	8.5577e-34
NZ_CP041607.1\|WP_060898117.1\|3450346_3451063_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	4.82115e-127

>NZ_CP041607.1|WP_143601345.1|3459189_3460554_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MSTPPLASGPEGPGALRPLLDTVLDALRDGGEARGGPLPAGGPESVARRVRDAVGDVLPEQGTEDALHVLVRALAEGAADPAHPLCAAHLHCPPLAVATAADLAASALNPSMDSWDQAPAASELEALVTRALAQEIGADDALVTTGGTESNQLALLLAREAHAGVRLIHGANAHHSLPRAAWLLGLPDPVVVPAPAGTMDLAALDEALTELQGLRGSLLVAATAGTTDAGLIDPLPDIADLCEAHGTRLHIDAAYGGGLLFSDHHRGKLDGLDRAHTVTLDLHKLGWQPVAAGLLVVKDPHDLDALSHRADYLNADDDTEAGLPDLLGRSLRTTRRPDILKVAVTLKTLGRAGLGALVDQVCARAVELADLVEAHPGFELYDPPTLSTVLFRPAEASDEAVAAVRRTLLHEGRAVLGRALLDDRLWLKATLLNPHTRPGDLAALLKLVEGHTPR
>NZ_CP041607.1|WP_143601344.1|3457771_3459193_-|SidA/IucD/PvdA-family-monooxygenase
MSPTPLPPPHESDAPRDLVGIGIGPFNLSLAALAQPLPELDSVFYEQRPGFDWHPGLLIDGATLQVPFLADLVTLADPASPWSFLNYLKDRDRLFPFYFAERFHMQRAEYDAYCRWVAGRLPGLHFGHQVDAVRWNPERTLFEVDFTQLDSEGEAEALGRTYTRNIVLGVGTAPHIPEPLKPLVDAPGVPVIHAADYLAHRESFLTAEHITVIGAGQSGAEVFLDLLRNRPAGREKIHWLARTEAFAPMEYSKLGLEHFTPDYTRYFHALTEPVRDRLVAAQWQLHKGIDADTIAAIHDELYRRTLHGGWPDAVLTPAVTVRTAGRVATTKVELHLEHGQQSARTRLVTDAVVLATGYRERPLGQILAGLDPYLRRDSAERPRIDDQFRLALDPAVTGRVYVQNAELHTHGVGAPDLGLAAWRSATILNSLMGKDPYPLPRRTAFTTFGLEPQSQVPPARHTAQTLTPLVDGR
>NZ_CP041607.1|WP_097284250.1|3455833_3457648_+|bifunctional-metallophosphatase/5'-nucleotidase
MPLNRRKFLKKSAVTGAGVALTGAVAAPSAQAATSAAAGGGKKPVKRHSLTVMGTTDLHGHVFNWDYFKDAEYKDAAGNAQGLARISTLVNEIRKEKGRCNTLLLDAGDTIQGTPLTYYYAKVDPITAKGGPVHPMAQAMNAIGYDAVALGNHEFNYGIETLRKFESQCRFPLLGANALDAKTLKPAFPPYFMKTFHVPGAPSVKVAVLGLTNPGIAIWDKAYVQGKLTFPGLEEQAAKWVPKLRSMGADVVVVSAHSGSSGTSSYGDQLPYVENSAALVAQQVPGIDAILVGHAHVEIPELKVTNAKTGGTVVLSEPLAYAERLSVFDFELVLEKGKWQVESVKASVRNSNSVADDPKITRLLKDEHDLVVAYVNQVVGTATDTLTTVEARYKDAPIIDLITKVQEDVVKAALVGTEYASLPVIAQASPFSRTSEIPAGKVTIRDLSSLYVYDNTLVAKVLTGAQVRAYLEYSANYFVRTAAGAVIDTEKLTNANNRPDYNYDYVSGLRYDIDIAQAEGSRIKNLTYNGAALDDAQQFVFAVNNYRANGGGAFPHVASAKEVWSESTEIRTRIAEWVTAKGVLDPKEFASVDWKLTRDGTPVF
>NZ_CP041607.1|WP_060898114.1|3454981_3455695_-|DUF541-domain-containing-protein
MAPTAEEPRPAVPYGTPESPRIAVRGEAHLEVDPEIARIGITVSARGTDRREALADLTRRNATAMDLVKSYGDAVERLETGAFSISPELTKHGRGERVRAYHGRVHLTAELTDFTALGELTTRLADLDLTRVDGPWWALRPDSPSHRQARQQAVREAVQRAREYAEALGTTLAALVELADIGAENAQPYPAAPGRAMRSMSFAGGTPEEAAPLDLEPERQHVYAQVNARFTMAPPEL
>NZ_CP041607.1|WP_054235994.1|3453394_3454831_-|pyruvate-kinase
MRRAKIVCTLGPATDSYDQLKALVDAGMDVARFNLSHGTHAEHEERYQRVRKASDETGRSVGLLADLQGPKIRLGRFTEGPVLLERGDTFTITVEEGAEGDRLTCGTTYSGLAADVTPGERILVDDGKVCLEVTAVDGPRVHTTVVEGGMVSDHKGLNLPGVAVSVPALSDKDEADLRWALRTGFDVIALSFVRSGRDIDDVHRIMDEEGRRLPVIAKVEKPQAVDAIDDIVAAFDGIMVARGDLGVEMPLEQVPIVQKRAIKLAKRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKYPVETVRTMSRIVEAAEEDILAKGLPPLTDRNKPRTQGGAVARAAAEMGDFLGAKFLVAFTQSGDTVRRLSRYRSPIPLLAFTPDPATRSQLNLTWGVETFLGPHVDSTDAMVDQVDELLLKYGRCKKGDIVVITAGSPPGVSGTTNLVRVHHIGEDDSPK
>NZ_CP041607.1|WP_143601343.1|3452608_3453385_+|helix-turn-helix-domain-containing-protein
MYDMGTRERALALVAQGRSLNSVSKETGVSRSAIRCWQSRVDPLPRMQRTPCSRCGATPEPPSNTAAYSYLLGLYLGDGCISPGMRAGYVLRIACANTWPGLIEACAAAVEAINPSKKSNRVRAVGYVSVVGYSRHWPCLFPQHGPGKKHERPVVLESWQQEIVDSHPWEFIRGLVHSDGCRITNWTEKVIAGERKRYEYPRYFFTNVCDDIRQLYTDTLDKLGIQWTHCTRDGNPFAISVARKTSVALMDAHVGSKY
>NZ_CP041607.1|WP_054235992.1|3451677_3452328_-|response-regulator
MTAPESPQPVADDDKSHVPPLTTRVVIAEDEALIRLDLKEMLEEEGYAVVGEAGDGEQAVELAREHRPDLVILDVKMPKLDGISAAEKIAEESIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRFTELKQLEKEVADLSQRLETRKLVDRAKSVLQTQYGLTEPAAFRWIQKTSMDRRMSMQQVAEAVIADAEEKKASKG
>NZ_CP041607.1|WP_054235991.1|3451171_3451555_-|DUF2267-domain-containing-protein
MEEKAFVQAVSERTGLTRQESADLTRATLETLAHRLSSGEARNLALELPEGLAESVRRGATAEIERFDYDELVRRVAQRNVLKPDEADGGVRAVLVTLREAISEKEFGHAMSQLGADFSRPIENFVG
>NZ_CP041607.1|WP_060898117.1|3450346_3451063_+|ABC-transporter-ATP-binding-protein
MTALLEVEDLKVAYGKIEAVKGISFSVEAGQIVTLIGTNGAGKTTTLRTLSGLLKPTAGRITFDGKPLSGIPAHKIVSLGLAHSPEGRHIFPRLTITENLQLGAFLRTDKAGIEKDIQRAYDLFPILGERRKQAAGTLSGGEQQMLAMGRALMSQPKLLMLDEPSMGLSPIMMQKIMATIAELKADGTTILLVEQNAQAALSLADQGHVMEVGNIVLSGTGQDLLHDESVRKAYLGED
>NZ_CP041607.1|WP_143601342.1|3449366_3450350_+|ATP-binding-cassette-domain-containing-protein
MTHMTTTTATSPVLEASGVTMRFGGLTAVRSVDLTVNSGEIVGLIGPNGAGKTTFFNCLTGLYVPTEGKVSYKGTVLPPKPHLVTSAGIARTFQNIRLFANMTVLENVLVGRHTRTKEGLWSALLRGPGFRKAEAASRERAMELLEFIGLDHKADHLSRNLPYGEQRKLEIARAMASEPGLLLLDEPTAGMNPQETRATEDLVFAIRDRGIAVLVIEHDMRFIFNLSDRVACLVQGEKLVEGTSEVVQGDERVIAAYLGTPFEGAPGAEELAEVEAAEAAEASAAPEPAEASETPESDETPEATETPEAAESDAAAEGTTSKEGNAQ
>NZ_CP041607.1|WP_143605357.1|3461519_3464018_-|aminopeptidase-N
MSPMSVLTRDEAQTRAQLLDVHHYGIALDVTHGDETFDSLTVIRFTARADADTFVELKPAELRSVTLDGQPLDPETLDENRLPLKGLTAGEHELRVDARMRYSRTGEGMHRFTDPTDGETYLYTQLFMEDVQRVFAAFDQPDLKAVFELSVTAPDGWTVLANGVTEHVGEGRWQAAPTPLISTYLVAVAAGPWHSVRTEHRGLPFGIHCRRSLAPYLDADADEILDVTRACFDRYHEKFDEPYPFDSYDQAFVPEFNAGAMENPGLVTFRDEFVYRSAVTDTERQTRAMVIAHEMAHMWFGDLVTLRWWDDIWLNESFAEYMGYQTLTEATRFTDTWTDFGVTRKPWGYDADQRPSTHPVAPDPDAVPDTASAMLNFDGISYAKGASALRQLVAWLGEKDFLAGINTHFARHKFANATLADFIDNLASATERDVHAWADSWLRTTGVDTLTPTLTAGPDGTHTLTVEHHGSRPHRIAVGLYDNDLGVEGRLTLRDRLEADVPGTEPTVIGKRPALLLLNDGDLSYAKVRFDPESFQTVRTALAGLPEPLTRAVVWNALRDSVRDGELPAMAYIDAARAHLPRESDLALVQGVLSFAATQVADRYLPAEDRPTALATLTDLCRDLIRRTEDGSHPGLRLTAVRHYIDVAAHPDTISAWFSEGTVPGGPELDPELRWRILGRLAVLGAIDDAVIEAELVQDPSATGQEGAARCRAALPDPEAKRRAWEEMFTSDHLSNYLFTATAQGFWQPEQTHLVREYVERYWADAVAVSARRGPAIADAAGRYAFPVHAVAPETLALGETCLRDGDPIPALRRKLVDQLDDLARALKVRTA
>NZ_CP041607.1|WP_143601346.1|3464100_3464691_-|response-regulator
MPSDAKILIVDDHEDTLYALESALAPLGHLVTRATSGDDALKEVLRGQVGLLLLDVRMPGVSGLDVVRYMRRVEQTQHIPVILLTGFGPDTELSATAFALGVADLVMKPVDPWTLRTKVRYLYDTHQRRRALEAEVRELRALTEERASPRAPGRLRHDTRVPPQRDGHTDARDARDVRGSRGSREALDAREQDRTA
>NZ_CP041607.1|WP_097288885.1|3464895_3465264_-|chorismate-mutase
MTTSDTGNTNDGAGGEVDPAVRAELARLRDSIDNIDAAVVHMLAERFKCTQQVGHLKAAHQLPPADPSREAHQIARLRRLAENAKLDPAFAEKLLNFIIAEVIRHHESIADGAGRGAAATGE
>NZ_CP041607.1|WP_143601347.1|3465275_3466160_-|helix-turn-helix-domain-containing-protein
MHHTWMRYFSPAPVHHRLGLVCLGVGLQHGELPTVGPRTLDHHVAVVVSAGGGWFRGPDGHHHTVTAPALLWLTPGVPHHYGPDPSWDECFVDFTGPATATYTELGYIEPDRPVVPLSDATGARATVGRIARAARRGNPLLEVETGAAVHELLVALRRARADLAPDGDPVLNALARDAFQPLSVAEHAARHGMTPAELRAAVRRGAGRSPKDYLLGIRLGRAKELLAATELPVAAVARRVGYDDPAYFSRLFTRRVGMAPVRFREQQGRTLPGGWSDRIPDPDDPPMIEPPHAT
>NZ_CP041607.1|WP_143601348.1|3466269_3468039_+|beta-galactosidase
MSEFTVGDTDFLLDGRPVRLLSGALHYFRVHEGQWGHRLGMLRAMGLNCAETYVPWNLHEPRPGEYRDVQALGRFLDAVREAGLWAIVRPGPYICAEWENGGLPHWLTGKPRTRDEEYVGHVERWFHQVLHEIVPRQIDRGGPVLMVQVENEYGSYGSDQVYLRRLADVLRAEGVSVPLVTSDGPEDHMLTGGSIPGVLATVNFGSRARAAFEVLRRHRPEGPLMCMEFWCGWFDHWGGEHVVRDAGDAAQALREILECGASVNLYMAHGGTNFAGWAGANRGGGALHEGPLEPDVTSYDYDAPIDELGRPTEKFWRFREILGAYADGPLPELPPAPAPLGAGAAVDLREWAALDAVLETLGGRDAEYPVPPTFEELDVDRGLVKYEVTVPGPRGPYPLLLRGLRDLAVVYVDGVAAGVLTEDDPGLKEPVAGHARVEAWVESLGRVNYGPRSGEPKGITGGMLHERQFLHGVRARGLRLDAFDAGGVGRVPFGGLSAEGGRGLYRGTVQVRGAGDAFLELPGWTRGFVWVNGFCLGRYWSVGPQRSLYVPGPVLREGANEVWLLELQEPSPTAPVLRRPDAAASAPGR
>NZ_CP041607.1|WP_097284255.1|3468580_3469441_-|serine-protease
MRATAVVSCGLGVPPRGFQPPTRGSTLKSSKKFTGVKRVLALGAVALATVSLQPVSAQAAPTPVVGGTRAAQGEFPFMVRLSMGCGGALYTQQIVLTAAHCVSGSGNNTSITATTGVVDLQSSSAIKVKSTKVLQAPGYNGKGKDWALIKLASPVNQPTLKIATTTAYNNGNFTIAGWGAAREGGAQQRYLLKATVPFVSDATCQQAYGSDLVPGDEICAGFVQQGGVDTCQGDSGGPMFRKDDSGAFIQVGIVSWGQGCAEPGYPGVYSEVSTFAADIARAASTL
>NZ_CP041607.1|WP_054236003.1|3469593_3470490_+|hypothetical-protein
MANGGPVEHGFPHLDTVRASITALYKRLSYDTIHTFATSVAPADVAFGDIDDLHLGAQRVAREMVHHYHLPDARLIIGFREMTQAANVELTAGPEYFVELNDRFRSHRRDIGAALAHEVMHVYLHRLDLYFPGTRDNEILTDTAATYLGAGWLLLDAYREDADSSQKLGYLTPEEFGYVLAKRALVFDEDPSIWFTSPQAYTAYTAGMAQARRDEQQPPLTAAGWAGRRRYAKDRRHAQDHHAPGPHPGVPYAFSPDSRGPLRVSFPCPTCHQRIRVPVRGRVRARCTLCRTVLECDT
>NZ_CP041607.1|WP_054236004.1|3470586_3471630_+|hypothetical-protein
MSTNDPAAHLFTAVHEGDEDAVVRLLRSGVSPDAVDEDGQTALYLAAVSDRPGVVRLLLVAGAAPDRLSQGTDAPLCGAACGGHTEVVRALLAAGAAPDTVEEFGFTALTWAVRLGRVAVVRELLAAGADPDRPGPTGEPPLVAAARRGSPGCVRALLRHGARARSAALAEAHRRLTADVETEVRAGLEETWGPGRPSVTHRYPEDGGITVEVQLLDPAGNPVASNDQQTGHAAIATLLESALGITAPAAELAARALRPADPDNDDWTEAATSLGLRGDEETFRAAVEWCAAPDPLRQAFGADVLGRLGNPHGLPILRVLTGATDPVIRDRAASALARLDSPGPSGP
>NZ_CP041607.1|WP_143601349.1|3471697_3472615_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSGPLLCEGRVVIVTGAGRGLGRAHALAYAAEGARVVVNDLGVGLDGTPGPDSPAARVVAEIRAAGGQAVAHGGDIATTEGAASLVRTALETYGRLDTLVNNAGFLRDRMLVNLDEDDWDAVLRVHLKGHFLPLKHAAAHWRAEAKDGRTPRARVVNTSSGAGLLGSVGQGNYSAAKAGIIGLTLVAAAELGRYGVQVNAIAPAARTRMTERTFADTMAAPDADSFDAMAPENVSPLVVWLGASASTGVTGRVFETEGGRITVMEGWRPGPTADKGARWTPSEAGDTALKLLAQAEVPGAVYGAG
>NZ_CP041607.1|WP_143605358.1|3472611_3473382_-|SDR-family-oxidoreductase
MDLGGRTVVVTGGTRGVGAGIARAFVEAGADVVVCARRPPDTPLEGTEFVSVDLRDPAAVHAFFAALPRLDVLVNNAGGAPYRPLTEADAGRHARVIELNLVAPLTASLAAYEHLRRARGSIVMIGSVSGTRPSPGSAAYGAAKAGLANLARSMAVEWAPDVRVNTLVVGMVRTELSHLHYGGEDGIAAVSRTVPLGRLADPSDIGGAAVFLASDAARYVSGASLLVHGGGERPAFLDAATANKAGTSGQDLGGLR

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Crispr_ID: NZ_CP041607_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_7

3685470-3685588

Orphan

Consensus_repeat	Method
CCAGCCCCCACCGGCCCGCAGCCAAACGA	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP041607_7

>merge|NZ_CP041607|7|3685470-3685588|CRISPRCasFinder
CCAGCCCCCACCGGCCCGCAGCCAAACGAATTCGGGTGGGCGGGGGGCGCGGGCGAAGCCCCGTCCTGGGGGCGCGGGGAACTGCGCGACCAGCCCCCACCGGGCCCGCAGCCAAACGA

>NZ_CP041607|7|6|3685470-3685588|CRISPRCasFinder
CCAGCCCCCACCGGCCCGCAGCCAAACGA	ATTCGGGTGGGCGGGGGGCGCGGGCGAAGCCCCGTCCTGGGGGCGCGGGGAACTGCGCGAC
CAGCCCCCACCGGGCCCGCAGCCAAACGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143601417.1\|3680910_3681216_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054230749.1\|3675634_3676258_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP041607.1\|WP_054229281.1\|3687178_3688618_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054229277.1\|3691805_3692507_+\|DUF4191-domain-containing-protein	unknown	unknown	gnl\|CDD\|379389
NZ_CP041607.1\|WP_143601420.1\|3684337_3685264_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|273800
NZ_CP041607.1\|WP_054229280.1\|3688920_3689718_+\|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl\|CDD\|184638
NZ_CP041607.1\|WP_143601418.1\|3681591_3682467_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|128941
NZ_CP041607.1\|WP_054229279.1\|3690237_3691203_+\|lipoyl-synthase	unknown	unknown	gnl\|CDD\|235493
NZ_CP041607.1\|WP_097284369.1\|3694781_3695099_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054229275.1\|3693291_3694701_+\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|273198
NZ_CP041607.1\|WP_097284365.1\|3685824_3687177_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|366721
NZ_CP041607.1\|WP_143601415.1\|3674695_3675343_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_097284360.1\|3680422_3680944_+\|DUF4240-domain-containing-protein	unknown	unknown	gnl\|CDD\|379426
NZ_CP041607.1\|WP_054230748.1\|3676522_3679225_+\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	unknown	unknown	gnl\|CDD\|236500
NZ_CP041607.1\|WP_054229278.1\|3691518_3691716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_060902030.1\|3682591_3683776_+\|MarP-family-serine-protease	unknown	unknown	gnl\|CDD\|379142
NZ_CP041607.1\|WP_060895232.1\|3692621_3693092_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP041607.1\|WP_143601416.1\|3679336_3680335_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP041607.1\|WP_143601419.1\|3683777_3684275_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP041607.1\|WP_054229287.1\|3695459_3696383_+\|zinc-metalloprotease-HtpX	unknown	unknown	gnl\|CDD\|179418

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_054230749.1\|3675634_3676258_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.93935e-34
NZ_CP041607.1\|WP_054229277.1\|3691805_3692507_+\|DUF4191-domain-containing-protein	gnl\|CDD\|379389	pfam13829, DUF4191, Domain of unknown function (DUF4191).	8.53396e-107
NZ_CP041607.1\|WP_143601420.1\|3684337_3685264_+\|TIGR01777-family-protein	gnl\|CDD\|273800	TIGR01777, Hypothetical_UPF0105_protein_Rv2216/MT2273/Mb2239., TIGR01777 family protein. This model represents a clade of proteins of unknown function including the E. coli yfcH protein. [Hypothetical proteins, Conserved].	6.08787e-134
NZ_CP041607.1\|WP_054229280.1\|3688920_3689718_+\|lipoyl(octanoyl)-transferase-LipB	gnl\|CDD\|184638	PRK14345, PRK14345, lipoyl(octanoyl) transferase LipB.	5.32996e-109
NZ_CP041607.1\|WP_143601418.1\|3681591_3682467_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	9.68732e-44
NZ_CP041607.1\|WP_054229275.1\|3693291_3694701_+\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NZ_CP041607.1\|WP_097284365.1\|3685824_3687177_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	1.89154e-42
NZ_CP041607.1\|WP_054229279.1\|3690237_3691203_+\|lipoyl-synthase	gnl\|CDD\|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0
NZ_CP041607.1\|WP_097284360.1\|3680422_3680944_+\|DUF4240-domain-containing-protein	gnl\|CDD\|379426	pfam14024, DUF4240, Protein of unknown function (DUF4240). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 169 and 263 amino acids in length. This domain is often associated with the WGR domain pfam05406.	1.0971e-49
NZ_CP041607.1\|WP_054230748.1\|3676522_3679225_+\|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	gnl\|CDD\|236500	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed.	0
NZ_CP041607.1\|WP_060902030.1\|3682591_3683776_+\|MarP-family-serine-protease	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	5.80766e-17
NZ_CP041607.1\|WP_060895232.1\|3692621_3693092_-\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	3.02779e-11
NZ_CP041607.1\|WP_143601416.1\|3679336_3680335_+\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.47824e-41
NZ_CP041607.1\|WP_143601419.1\|3683777_3684275_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.03752e-17
NZ_CP041607.1\|WP_054229287.1\|3695459_3696383_+\|zinc-metalloprotease-HtpX	gnl\|CDD\|179418	PRK02391, PRK02391, heat shock protein HtpX; Provisional.	4.47918e-173

>NZ_CP041607.1|WP_143601420.1|3684337_3685264_+|TIGR01777-family-protein
MNDSPLAPDSRRSRVAIAGASGLIGSALTRSLTADGHEVVRLVRRAPRGKDEVRWDPDGQRMDAAGLAGCAAVVNLAGAGVASRRWTEAYKRKILDSRVRGTATLAAAVASLDERPRVFVNGSAIGFYGETGDRVVDESAPPGEGFLPSVCVAWEGAAAPAREAGVRTVFARTGLVVAREGGAWGKLFPLFKAGLGGRMGDGRQYWSYISLHDEVAAIRHLIDTSSLSGPVNLTAPTPLTNREITEAMGRVLHRPTVFPTPAPLLRLALGDMSGDILGSQRVHPTRLLSSGFAFAFPSIEEALLAALR
>NZ_CP041607.1|WP_143601419.1|3683777_3684275_-|GNAT-family-N-acetyltransferase
MTFMPVPHIRIATLDDEDALGRLDRVTWSTQHAVMPRPQPPYEPFYNERFGPRDHHVAELDGVLVGYIRLGYPTPLACNSHVRQIQGLVVAEEARRAGVGRELLRAVMDGARRQGARRITLRVLGHNAPARKLYESEGFQVEGVLPEEFLLDGQYVDDVFMGRFL
>NZ_CP041607.1|WP_060902030.1|3682591_3683776_+|MarP-family-serine-protease
MDLLDILLLLVILAYAASGYRRGLVAGCVSLAGFVGGAVIGVWVLPWMMDLVTAGTSAATVTAVLTVLVPAVVGHELAGRLALKLRRELDQGPLRVADGVGGAAANTVAVLLVAWVAASVLGASSSTLITQSIRNSALLGAVQTAMPDTTPTWFSRATSALTEAGFPQVFNPFENEPTAGVAKPSGDSVTAAATSAAKRSTVKIEGAAGNQGREGSGFAYAAQHVMTNAHVVAGIDNPTVRVGGVGRVYSARVVFFDPRKDVAVLYVPDLRVPLLRFDDSAKRGDSAVVAGYPQDGGLDLQAATVAGRINARGQNIYNSSMVTREIYSIRSTVRPGNSGGPLLTTGGRVYGVVFARSTSDNETGYVLTADEVAGDAQRAATATTPVDTGDLITS
>NZ_CP041607.1|WP_143601418.1|3681591_3682467_-|N-acetylmuramoyl-L-alanine-amidase
MVPPGGTAHIAGGPEPGQGGSMRVFRKARGAWTRLARRVWARRATVVVLGCVPGLLAVLALVVCAVGVDRKVVARERPVAAPLPAGPHRGARPVIVPRSRWLDAGSAHAQPPARYDDHVVAVFVHHTDSPNAYECAEAPRIIRSLYAGQTGVRRWDDIGYNFLVDRCGTIYEGRAGGVDRAVTGAHTQGFNHGTAGIAAIGTFGAGTPVPRAMTEAIASLAAWKLGLSDVDPRATVRLVSSNDLSRYTAGTSAVLPTLAGHDAGFMTNCPGAALASQLPGIRSRAAHLQGR
>NZ_CP041607.1|WP_143601417.1|3680910_3681216_-|hypothetical-protein
MSSRRTEKTGKANRAAGARGWNTALRTPWTVACAVVTVLVGPAAATASALDRANAAPPYHAHENHENHEDHESHKNRETRLPYVTPYATLPQSLKRSHSLG
>NZ_CP041607.1|WP_097284360.1|3680422_3680944_+|DUF4240-domain-containing-protein
MMDETEFWELVDTTREAVEGDPEDHADLLVERLVQLDPDAVLDFARHFEARYNRAYRWDLWGAAWVLLDGVSDDAFDFFRCWLIGQGREVFEGAMHDPDALADLLDDFDEDLDGDGEELGYAADEAYEQLTGVVAPDLGIPPASPEPEGTPLDFENESVLAERYPKLWERFRD
>NZ_CP041607.1|WP_143601416.1|3679336_3680335_+|WYL-domain-containing-protein
MRAARLIKMVLLLQSRPSMTAGELARELEVSERTITRDAQALSEAGVPVYADRGRAGGYRLIGGYRTRLTGLARTEAEALFLSGVPGALRDMGLEDAASAARLKVSAALLPSLRDASRAAGQRFHLDAPAWFDEPETPELLPVVAEAVWDDRRITAGYRRGTAEVERVLEPYGLVLKAGVWYLCARVPEPGPGGSGPYRVYRIDRFTEVRPATECFTREDGFDLPGFWAERAGQFARSILRAEAVVRLSPEGVRRLAYVVDPASARQALDGCGDPDGRGWVTVTLPVESEEVAHAQLTGLGPEVEVLSPAALRERFAGDAVRLAALYRENAS
>NZ_CP041607.1|WP_054230748.1|3676522_3679225_+|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type
MTDPTAIQPSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAYLMRRTLERAEGNGLALPKLLETDYVNTIPTAAEPVVDGDEAMEARITAWNRWNAAAMVTRGAKHGVGGHIATFASAAWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLTEQHLDNFRQEAGGNGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTSRGIKDVSQSHVWAFLGDGEMDEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKSLWGSAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGADPALVEMAKLLSDDKITECFHLSRGGHESRKVYAAYRAALAHKGAPTVILAQTVKGFTLGEGFASKNANHQMKKLSTDEFKQMRDLLELPISDSQFVDGVVPYGHPGADSPEVRYLQERRAALGGPAPARRTHALAPLPAPADKAFASFDKGSGSQNVATTMAFVRLIKDLVRDKETGKRWVPIVPDEARTFGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTAYATHGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPVIAATNPAALSYDPAFAYEIATIVKDGLRRMYGEAAPGEDSNVFYYLTVYNEPMPQPAKPAGLGIDEGIVKGLYRFNTAESAGLSPVANAPRIQLLGSGTAIHWTLQAQKLLAEEWGVAADVWSATSWTELRRDALEADAALLRGEERMPFVRQALHGAEGPVLAVSDYMRQVPDQIAQWVEQDYSSLGADGFGLSDTREAARRHFGVDAQSIVVAALAQLARRGEVKASAVKEARERYGL
>NZ_CP041607.1|WP_054230749.1|3675634_3676258_+|GntR-family-transcriptional-regulator
MTAPVVHSLREQIREHIVEGIVSGRWKPGERIVERRIATELEVSQTPVREALRELESLRLIESAPNKGVRVRNLTAADLEESYPVRAGLEAIAAELAAERLAQDCSALEPHVTALYEADRLSDGTGQVRHTVAFHRELVRAAGNSVLLHTWEGLGIEVFTALSIRWLGTVQQSYAEEHEALVDAFRRRDPLIADLVKAHVLGCAPRP
>NZ_CP041607.1|WP_143601415.1|3674695_3675343_-|hypothetical-protein
MGGWGRKRGLRWAAAAGAVAAVAACGPVDTGAAVRPSAARAHGTPVASGGACVFVKPDGARKFGHVGWGFRITGTDRWVYGAVENPSNALYTPPGGDIGAWHAEGTYARMLGDMSRDAHFPGKSTHPYSRYRCTDSSTSDVNSARAMIRKVEKRGFLVGVDPETGDLGSRDCLDATYDVLRAYRTRHLTPAYPTEIPNLWVETLVLWSDSALKPR
>NZ_CP041607.1|WP_097284365.1|3685824_3687177_+|FAD-dependent-oxidoreductase
MLEPVSKADVDVVIVGAGAAGLAAAQHLTRAGLTTKVLEAAPTVGGRMTTEKVDGFRLDRIGRLLSTSYPELHRTPGLNTLALRPFSPGVLLHSDGRHHRAAAPTTPRSARGALTAARALASAPRLPRSQSSRPGPLGGHLDQTRLATALARLAVTPPERLLTRPDLPTAHALTTRGLPPRAVDGFLRPLLAALLCDPALTTSSRAADLALHSFASGRLCLPEGGADTLPELLAASLPPGTVHTGVEVTAVSTTTVTTKDHGELSCRAILLATGARAAARLLPGLRVPAFHPVTVLHHTTDEPPLTDPALLLDADRSGPVAQTAVISQVDPSRAPAGRALVSSTVLGTPPAAAHLDTAVRAQLARLYGTSTTRWELLAVHHTRDAVPAMPPPHDLRRPVRLLAGLYVCGDHRDTGTVQGALHSGRRAAHALLMDLGARPAATEEPLETAA
>NZ_CP041607.1|WP_054229281.1|3687178_3688618_-|hypothetical-protein
MTERPAQRTPNRQLAALIAEAGFSNAGLARRVDQLGLEHGLDLRYDKTSVTRWLRGQQPRGTTPALIAEVFTRRLGRRLTAQDLGLDACAPVYAGLEFAATPEEAVDIVSGLWRKDSGSHAELRKIAFTPAGLVVPSRDWLIGRADDRVSRGDQAAARIPAQGRPAVPRQRSQTERGPGQKVTGGDIAALRSVGELFRALDHAYGGGHARQALVRYLEHEAEPMLRGAYGEQTGRRLFAAAADLTRLAGWTSYDIGAHGLAQRYFVQALRLSQAAGDRAYGSYVLVTMSRQAVYLGHGREAVQLARVAQQGVGSSVPPVVQALLHSVEARGHGVLGEVRACTASLVRAERALESARPGDEAPHWARFFDEAQLADEFGHCHRDLQQYRAAAQHAERSLQLRAPGFARSRLFCRVVLASARLGLGELDQACLLGAEAAGQAAEMRSVRAVEYVRDFERRLEPYRDAAPVRGYRDRVAALG
>NZ_CP041607.1|WP_054229280.1|3688920_3689718_+|lipoyl(octanoyl)-transferase-LipB
MSELRFVRMGFGAEAVEYQEAWDEQRRVHAARFLDEVPDTCLLLEHPPVYTAGRRTADSERPLDGTPVVDVDRGGKITWHGPGQLVGYPIQKLPRPVDVVAHLRRLEEVMIRVCAEFGVETSRVEGRAGVWVLGDPVAARPSLGGLSLDFDPRLTDEEFDPRLNGPEYAPSNAGQRREDRKICAMGIRVAKGVTMHGFALNVNPDTSSFDKIIPCGIRDAGVTSLAYELGRDVTIAEVLPVAEKHLRDVLENADLRPREVERASA
>NZ_CP041607.1|WP_054229279.1|3690237_3691203_+|lipoyl-synthase
MSAVAPDGRKMLRLEVRNAQTPIERKPEWIKTRAKMGPEYTKMQNLVKSEGLHTVCQEAGCPNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPEALDRDEPRRVGESVVTMDLNYATITGVARDDLEDGGAWLYAETVRQIHRQTAEREAGRTKVELLAPDFNAEPAQLAEVFSSRPEVFAHNVETVPRIFKRIRPGFRYERSLKVITEARDYGLVTKSNLILGMGETREEVSEALTQLHEAGCELVTITQYLRPSVRHHPVERWVKPHEFVELKEEAEQIGFSGVMSGPLVRSSYRAGRLYQMAIEKRGAYVASQAV
>NZ_CP041607.1|WP_054229278.1|3691518_3691716_+|hypothetical-protein
MQAAPVRATAIPSFTDALRAVESLLMSSGQRTARRNAWTSVLEDRRRAKDRVEAQRVLESVATRS
>NZ_CP041607.1|WP_054229277.1|3691805_3692507_+|DUF4191-domain-containing-protein
MARKETAADAANPGRLKQIALTYKMTRKADSKIGLVLAAVGIVTFGVFLAIGLLIDHPFYLGILGLLLAFLATAIVFGRRAERAAFGQMEGQPGAAAAVLDNIGRGWTTTPAVAMNRSQDVVHRAVGKAGIVLVAEGNPNRVKSLLAAEKKKMARIVADVPVHDVLVGSGEGQVELKKLRTTMLKFPRVLTGPQVTATNDRLRAMGDLMSNMPLPKGPMPKGMRMPRGGPKAR
>NZ_CP041607.1|WP_060895232.1|3692621_3693092_-|RDD-family-protein
MDNRQAIGSWLSGPRAALEDAGADLGYRGEQLGLPEQGPGSIARPGRRLGALAIDWALCLLIAYGLLTHGYKPGATGNWALLVFFVLGVLTVGTVGFTPGKRLLGLRIVPEGGGRLNPLRVLLRTALLCVAIPALIWDRDGRGLHDRLARTIEVRA
>NZ_CP041607.1|WP_054229275.1|3693291_3694701_+|type-I-glutamate--ammonia-ligase
MFQNADEAKKFIADEDVKFVDVRFCDLPGVMQHFTIPAEAFDPAEELAFDGSSIRGFQAIHESDMALRADLSTARVDPFRRDKTVNINFFIHDPITGEQYSRDPRNVAKKAEAYLASTGIADTAFFGPEAEFYVFDSVRFDTKSNEAFYHIDSEAGAWNTGALEDNRGYKVRYKGGYFPTPPVDHFADLRAEISLELAKSGLQVERQHHEVGTAGQAEINYKFNTLLAAADDLQLFKYIVKNVAWRNGKTATFMPKPIFGDNGSGMHVHQSLWANGDPLFYDEAGYAGLSDTARYYIGGILKHAPSLLAFTNPTVNSYHRLVPGFEAPVNLVYSQRNRSAAMRIPITGSNPKAKRVEFRAPDSSGNPYLAFSALLLAGLDGIKNKVEPAEPIDKDLYELAPEEHAGVAQVPTSLPAVLDRLEADHEFLLAGDVFTSDLIETWIDYKRTNEIAPLQLRPHPHEFELYYDV
>NZ_CP041607.1|WP_097284369.1|3694781_3695099_-|hypothetical-protein
MKAQRARRFFAVSAIGVLMAGGAAIGAAGTASAAAPAQAQTHVTNGCSNWGGRGFGNCGFGFNNGFNTGFNRFGFNNGFGFNNGFGFNNGFSNGFGGGVVVIVVP
>NZ_CP041607.1|WP_054229287.1|3695459_3696383_+|zinc-metalloprotease-HtpX
MQSRFRSDPRLTVRMTVTLFLLGLLYVAFVAALIVLLKSWVLVVVVAALVLGAQYWFSDRIALYAMHGRIVEREEYPQLHGVVDRLCAVADMPKPLVAVSDIDMPNAFATGRNADHAVLCVTTGLLRRLEPDELEGVLAHELSHVAHKDVAVITVASFLGVIAGLIVRFAFYSQLFGGRGRKDQNTVAIFMAVMAVSAAVYAISFLLIRALSRYRELAADRSAALLTGRPSALASALTKVSGDIARIPTKDLRTAQAFNAFYFTPAFGAEPGIAKLFSTHPSLEQRLEQLGRISAELGEAATPENTA

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Crispr_ID: NZ_CP041607_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_8

3979683-3979771

Orphan

Consensus_repeat	Method
CGCCGAACAGGCTGAATGGTGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_8

>merge|NZ_CP041607|8|3979683-3979771|CRISPRCasFinder
CGCCGAACAGGCTGAATGGTGCGCACCGGGGTGGGTGGGGCATCGGCCTTCGGCCTTGTCCTCAATCGCCGGACAGGCTGAATGGTGCG

>NZ_CP041607|8|7|3979683-3979771|CRISPRCasFinder
CGCCGAACAGGCTGAATGGTGCG	CACCGGGGTGGGTGGGGCATCGGCCTTCGGCCTTGTCCTCAAT
CGCCGGACAGGCTGAATGGTGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143601520.1\|3971299_3973822_-\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|224389
NZ_CP041607.1\|WP_143601525.1\|3979465_3979681_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143601521.1\|3974626_3974956_-\|DUF2568-domain-containing-protein	unknown	unknown	gnl\|CDD\|378498
NZ_CP041607.1\|WP_060901990.1\|3988360_3989365_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176198
NZ_CP041607.1\|WP_060899262.1\|3985556_3985991_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP041607.1\|WP_060899263.1\|3984412_3985432_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176190
NZ_CP041607.1\|WP_143605382.1\|3980054_3980918_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143601523.1\|3977334_3978588_+\|pyroglutamyl-peptidase	unknown	unknown	gnl\|CDD\|238279
NZ_CP041607.1\|WP_143601522.1\|3976262_3977204_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176115
NZ_CP041607.1\|WP_054233605.1\|3989581_3990550_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143601526.1\|3981213_3983772_+\|peptidase-M28	unknown	unknown	gnl\|CDD\|349463
NZ_CP041607.1\|WP_097284537.1\|3970336_3971173_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370676
NZ_CP041607.1\|WP_143601527.1\|3986131_3986836_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367156
NZ_CP041607.1\|WP_143601524.1\|3978630_3979455_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225528
NZ_CP041607.1\|WP_097284553.1\|3983857_3984277_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP041607.1\|WP_054233607.1\|3987206_3988364_+\|mandelate-racemase/muconate-lactonizing-enzyme-family-protein	unknown	unknown	gnl\|CDD\|239432
NZ_CP041607.1\|WP_097284545.1\|3975409_3976222_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_CP041607.1\|WP_054233604.1\|3990682_3991804_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380649
NZ_CP041607.1\|WP_097284540.1\|3974012_3974588_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP041607.1\|WP_054231019.1\|3974981_3975398_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|223329

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143601520.1\|3971299_3973822_-\|glycosyl-hydrolase	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	1.07325e-59
NZ_CP041607.1\|WP_097284553.1\|3983857_3984277_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	6.39029e-71
NZ_CP041607.1\|WP_143601521.1\|3974626_3974956_-\|DUF2568-domain-containing-protein	gnl\|CDD\|378498	pfam10823, DUF2568, Protein of unknown function (DUF2568). One member in this family is annotated as yrdB which is part of a four gene operon however currently no function is known.	2.89624e-14
NZ_CP041607.1\|WP_060901990.1\|3988360_3989365_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	2.22104e-77
NZ_CP041607.1\|WP_060899262.1\|3985556_3985991_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.32542e-17
NZ_CP041607.1\|WP_060899263.1\|3984412_3985432_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	1.49795e-180
NZ_CP041607.1\|WP_143601523.1\|3977334_3978588_+\|pyroglutamyl-peptidase	gnl\|CDD\|238279	cd00501, Peptidase_C15, Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from proteolysis by other proteases until the pGlu is removed by a PGP. PGPs are cysteine proteases with a Cys-His-Glu/Asp catalytic triad. Type I PGPs are found in a wide variety of prokaryotes and eukaryotes. It is not clear whether the functional form is a monomer, a homodimer, or a homotetramer.	0.000137814
NZ_CP041607.1\|WP_143601522.1\|3976262_3977204_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.75154e-43
NZ_CP041607.1\|WP_143601526.1\|3981213_3983772_+\|peptidase-M28	gnl\|CDD\|349463	cd06244, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	3.24438e-67
NZ_CP041607.1\|WP_097284537.1\|3970336_3971173_-\|hypothetical-protein	gnl\|CDD\|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	7.92033e-06
NZ_CP041607.1\|WP_143601527.1\|3986131_3986836_-\|hypothetical-protein	gnl\|CDD\|367156	pfam02724, CDC45, CDC45-like protein. CDC45 is an essential gene required for initiation of DNA replication in S. cerevisiae, forming a complex with MCM5/CDC46. homologs of CDC45 have been identified in human, mouse and smut fungus, among others.	2.44024e-05
NZ_CP041607.1\|WP_143601524.1\|3978630_3979455_-\|hypothetical-protein	gnl\|CDD\|225528	COG2981, CysZ, Uncharacterized protein involved in cysteine biosynthesis [Amino acid transport and metabolism].	7.40326e-28
NZ_CP041607.1\|WP_054233604.1\|3990682_3991804_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380649	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system. Periplasmic aldose-monosaccharides binding protein ChvE that belongs to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	1.38116e-152
NZ_CP041607.1\|WP_054233607.1\|3987206_3988364_+\|mandelate-racemase/muconate-lactonizing-enzyme-family-protein	gnl\|CDD\|239432	cd03316, MR_like, Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. Members of the MR subgroup are mandelate racemase, D-glucarate/L-idarate dehydratase (GlucD), D-altronate/D-mannonate dehydratase , D-galactonate dehydratase (GalD) , D-gluconate dehydratase (GlcD), and L-rhamnonate dehydratase (RhamD).	6.83511e-138
NZ_CP041607.1\|WP_054231019.1\|3974981_3975398_-\|RidA-family-protein	gnl\|CDD\|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	8.2912e-24
NZ_CP041607.1\|WP_097284540.1\|3974012_3974588_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.64747e-12
NZ_CP041607.1\|WP_097284545.1\|3975409_3976222_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	4.53068e-58

>NZ_CP041607.1|WP_143601525.1|3979465_3979681_-|hypothetical-protein
MWTGPEASPVHPPPGPPAHPGPYHSARPAFEDEAVQAVRGSRGRSAPGGGEGAEPLGDGTGRGGGGEEKGR
>NZ_CP041607.1|WP_143601524.1|3978630_3979455_-|hypothetical-protein
MRDVGAGFGYLIQGQRWVARHGKQYGFGLLPGLITLVLYAAALVTLALYGEDFVTWSTPFADDWSSPWLGLFRGFLTAVLFALALLLAVLTFTAVTLLVGQPFYESLSEKVDRDVSPDGTAPESGLPLWRELWISARDSLRILVRAAVWGVLLFALGFLPFIGQTVVPVIGFFVTGFFLTEELTAVALQRRGVDLRDRLTLLRSRKTLVWGFGTPLGLAFLVPFVAVFLMPGAVAGATLMARDLLDEETDEPDDDHDDHGGHGNHDDHEQRAAV
>NZ_CP041607.1|WP_143601523.1|3977334_3978588_+|pyroglutamyl-peptidase
MTHIRVRLGAGVLGLALVGGLAAAPTASAAAAAPVTVEEQRLDQAAPQEILRRSGFDTVAPGFARALERAGSFGQAERVVVRQGARLWQRAVDRAQGRGPAGGDLSRDDDRPLYWARLGMTREVRQWEPEFGLTDTQRARLLAELEENSRGENTIRYPHAKGVKRILLTGFDPFTLDRDVRISNPSGATALALDGTTILTADGPARIETAVFPVRWQDFAEGTVERTLRRQLPRVDLFTTVSQGRVGRFDVERTNGAWRGGFPDNENVSRTETIPVTDPVSQPQWTSTTLPYARIVAAPTGRFPVYDHTSVTEIPAGGTDPVVRPDGPTPGSTARAGGGGDYLSNEIAYRATLLRDRLGLHDSLPGGHVHTPVLQFGTGNTDPATGTVTDPEFVRNRLDIIAQVRAIVTVAVSGTGR
>NZ_CP041607.1|WP_143601522.1|3976262_3977204_+|LysR-family-transcriptional-regulator
MSSMALMPNPHAVPDLSTTWLRVFLEVARHGSFTVAARALGWTQSAVSRQIASLESALGGAPLFDRLPRGVRLTEAGRFLVPHAEAVVERLHDANRELAALRRVAGGRLRFGAFATADAALVPRAIAAFRVRHPGVRLTREEGLTPVLLERLSAGGLDLAIVSTTGRAPLDPYTLHHLLDESLYVAVPADHPLAAEPSVRLPQLADADWISGSARPEGTLLDAALRHGFRPRVAHVVAEWTAKQGYVAAGLGVTLVPALAAESVRPDIALLAVRDDEAPARAVYAATVRGRSLGPAARAFLGALREAATHLPT
>NZ_CP041607.1|WP_097284545.1|3975409_3976222_-|NAD(P)-dependent-oxidoreductase
MEKIAFLGLGHMGAAMARRLLAAGFPLTVWNRTAEKAEPLVAEGATLAPSPAEAVRDADVVITMLANPAALDTVADAIVPELRRGTTWVEMSTVGPDVVKELAARLGEGVTFVDAPVAGSTDKAAAGQLGILAGGELTGVGHVLVHMGTVTRTGPLGSGAALKLIVNTALLGGVALVAETMALADKLGIDEKVARTALANGPLGGAVGRAFAEDVHFATALAAKDVALATKVAELPVLEAVLEHYKRAAADPAVAGADITKAVEHIRRSA
>NZ_CP041607.1|WP_054231019.1|3974981_3975398_-|RidA-family-protein
MQITLDNPPSAPGPANGYYSQVARVELPGAGALLYLSGQVAEGADLTEQSRGVFETIDALLGAHGAGLADIINIRTYLTDITQLPAYGAVRAQYLTGAPPTSMTFEVSRLFKPEALIEIEVVAAVPAVPAPRDAHGPE
>NZ_CP041607.1|WP_143601521.1|3974626_3974956_-|DUF2568-domain-containing-protein
MKAVNLGVLFLIELGALAAVGYWGFTRAAAAPLTWLLGLGAPAVLITLWALFGSQKASYKTRGAVRVGFELLWFGAGVAALAFAGANGWAIAFAAVCAVSKTLAVIWHQ
>NZ_CP041607.1|WP_097284540.1|3974012_3974588_+|TetR/AcrR-family-transcriptional-regulator
MPYGDAMGTRARSEERRAEIVRAALEVIAERGYRGASMASVAERVGLTQQGLLHYFPTKDALLVAVLKERDQWDAVPDTQWRVDLLASLVEYNAMRPGIIQTFSALLGESVTEGHPAREYFTERYARVRASMAAVLRAEYGERLPNGLTPERTAPLLVAVMDGLQFQWLLDPESVDMPGAFRDFLALLGED
>NZ_CP041607.1|WP_143601520.1|3971299_3973822_-|glycosyl-hydrolase
MAGTRTPADEAREAVVEAALGKLDLDAKTRLLAGQDMWSLPALPEIGLKSLVMSDGPIGVRGVHWTADDPSIALPSPTALAATWDPALARRAGTLLAQEARRKQVHVLLAPTVNLHRSPLGGRHFEAYSEDPYLTGEIGSGYVQGVQSGGVGTTVKHFVANDAETDRFTVNNLLSERALRELYLAPFEAIVAHAHPWGIMTAYNTVNGTTMTEHHHLVNEILRGEWGFDGFNVSDWTAARATAGALEGGLDVAMPGPRTVYGEALAAAVRAGEVEEAKVDEAVRNVLRLAARVGILEGAEPVVTEPPATVDGEALAREIARRSFVLVRNQGALPLEGGRGEGHGEARGEGHKVALIGAAARDARILGGGSATVFPARVVPPLDGLTAALPEGSLTYAVGADPNEELAVADRGFTLRAVCRDRDGAVVGTGSAPNGQIQWMGDDLPEGVTHATLHSVELTGTFTPRESGTHTLGIKGLGAFTLTVDGTVHFDDIQRGTKDDPFEAFFGAPVERAQVDLVAGETYEVALRHVIVVPEGAPLKVVGFALAHQDPRRDPDELIAEAVEAARAADTAVVVVATTDRVESEGFDRKDLRLPGRQDELVHAVAAANPNTVVVVNAGSPVELPWREEVAAVLLSWFPGQEGGAALADVLTGAHEPGGRLPTTWGSLTAAPVTQVVPADGELPYTEGVFIGYRAWEKEGRTPSYAFGHGLGYTDWTYESIELGDGGAGAGSGAGSGSDSGTTTVTVRVRNSGARAGREVVQVYLAPVEADAERPARWLAAFAGVEAGPGESVDVVLVLPRRAFEVWDESTGAWVFVKGSYEIAAGRSIVDRRVAATINV
>NZ_CP041607.1|WP_097284537.1|3970336_3971173_-|hypothetical-protein
MYPGQQPGPYPPQGPYQGQQPSYPPPQQVPYPPQYQQQPQAPQQHLGEGEMRLDPHLTPDQRQLVLRIQQQAKTYAYGFVLGIPLTFGGAHYGITRTPVGFAATAVGLVAVAVGLFAMTRMRALKQQLRLITPDAWRSPAAHLPGARKAATLAAYLNGVLVLLSLGAAGYLLYKGAGWGAYGNSFGFGALVLGAFIPFGMGIAAATTIPQLLRVIPAGAKVGRSLYSIIMVLATTVLVEGIKGKSPLPALIGAVVVAVCLGAMTLLGRATKRMRGESV
>NZ_CP041607.1|WP_143605382.1|3980054_3980918_-|hypothetical-protein
MPSLPSIPSRDDVLRMARSTTDITGQLLDTAGNITRIALNTFDPRDGSGAEALRVLRETTAELAEASASPQAQEAFYRIVDTLTRLGTTGAPLAVHPVSRPAQALLAALGDSLLPILDAVEPAVQEAADALGDLLEAGSPLLPAVAGVAAGALLALTPVIRATADVLRDSSPELRRIADALTSALAPLLPLQVALAERAAAAGVGVVRAALPPLADLTEAAAATTDAVRPVLIAGEEFLVSGLEHLQPLLLASASRTGRVARAVAVRVSAAVSPTAERGLVVAVTPT
>NZ_CP041607.1|WP_143601526.1|3981213_3983772_+|peptidase-M28
MRLPRPVLIATVLTAATGSLLLAPPSATADREPPVREGTDQPTGAARAPANAARNALTSPVIDLSDSGLAAPRRGYPREQVLSPDPENPADKSIKLGLTPYHAIAPKLNALQRLGDRVSVEVAGRSAGGHRLYLVTVTAPESARESLDQERMRELIENAPQAAAKDPAVKASYKTPVFFDNNIHGNEWEGTDAALQLIERLASAKDAQTTDLLAHSRLYFNITANPDGRIAGTRANANGFDLNRDFITASQPEARAIRQIAIDKQPAVMLDLHGYVNGTLIEPTTPPHGENYEYDLFLKNTYANALGMEAAVNGLGHTPAKDGVEPVQIPFRDQREGWDDWPPIFTPQYQAFHGAVAAHTVEIPLAVNNSEYDTLPVAELRRRSAINVDVAGAAMRATLAYARTHRASIIADQIEVFRRGATGAAQVPVSAETVPGVPGIGPEDVYTTDFPRAYVIPAGGAQRSATAAARLVDHLLANDVRVTRATRDFRLAGRSYAKGSYVVDLHQPKRGLANVMLADGRDISDKVSVMYDISGWSLGRLWGATVVPVRSGGLSAVATRRVEAAARVGYVAPRGDLRLRLDTPQEIAALNSLLEQGVSVRRLADGSVVVPGSARARAAALARTYDVAFDATGQTRTTEGSPGTPLHRVRVAAAVTPGELFALREMNFDVVPVSTAVLNAGFDWSAVDVLFVSSGLDHAGLNEGARAALDAFLHTHGLVGRGAVGAALNSAAGLLAVRPVEGNGDANGVVRVVNSGGPLTANAPDHGFVYAPVWFTDLGPGVRVEQAYAPGDPLVSGHWRPLADGTGGPEAAGGQAAVVSGPHAVLFGTEPLFRDHPKGEFPQVGRALLTVS
>NZ_CP041607.1|WP_097284553.1|3983857_3984277_-|organic-hydroperoxide-resistance-protein
MSIQQTDVLYTAVATAENGRDGRVATDDGRLDVVVNPPKEMGGSGAGTNPEQLFAAGYSACFQGALGVVARRENADVSGSTVTAKVGIGKNEDGFGIIVEISATIPNVDGATARDLLEKAHQVCPYSKATRGNITVTLV
>NZ_CP041607.1|WP_060899263.1|3984412_3985432_-|NADP-dependent-oxidoreductase
MTETQLPAVNREWHLVSRPVGWPKPEDFALVEAEVPQPGEGQVLVRNAYVSVDPYMRGRMSAAKSYVAPFELGKVMQGGAVGEVIASNAEGVEVGDHVLHFFGWREFAVVDAKQAVKVDPQAAPLSTYLGALGMTGLTAYAGLLRTASFKEGDSVFVSGAAGAVGSQVGQIAKLKGASRVIGSAGSDEKVKLLVEEYGFDAAFNYKNGPVSEQLRAAAPDGVDVYFDNVGGDHLEAAIGSLNRDGRIAVCGMISVYNSTEPVPGPKNLARLIQTRGRIEGFLVGDHYDLQAQFVQEVGAWVRSGELKYSETVVEGIENNLEAFFGVLRGDNVGKMIVKL
>NZ_CP041607.1|WP_060899262.1|3985556_3985991_+|MarR-family-transcriptional-regulator
MATQRTTRIDPLTLEVVDLIGTVVARYHEEYEDAAAEHALTGAQARLLSLLSLEPLPMRRLAQKLKCEPSNVTGIVDRLEARGLVERRPDPSDRRVKLAAATEEGRRVARSLRDALNFAREPLAGLSTEERLSLRDLLQRMLAP
>NZ_CP041607.1|WP_143601527.1|3986131_3986836_-|hypothetical-protein
MRAGTGAGAVDAGVDSLYEGDNDDDEDPDDEDEDGEGERSGRAAARRRNRGRGRGRGRDSEGPGGASRRDRKAAAHRRRRRRVLLIAAGFVLAAGGLSLAELGIDGPGLLPKPAAAGGEPADGSASSDAGTARPITDAGGSSGGTSTATASPDASASPSASKSAKGDKSKDDKKKGTQEQSATTGTGVVPSATSGPVSSTPPKSSPKPTAAPTSAAPSPSPSPSRCNRFLWWCT
>NZ_CP041607.1|WP_054233607.1|3987206_3988364_+|mandelate-racemase/muconate-lactonizing-enzyme-family-protein
MRITGISTHVVGTPWRNLTYVQVHTDEGLTGVGETRMLGHTDALIGYLREAEANHILGSDPFAVEDLVRRMKYGDYGRAGEIVMSGIAVIEMACWDIKGKALGVPVWQLLGGKVTDRVKAYANGWYTTERTPEAYHKAAQEVVARGYKALKIDPFGTGHFELDHEATLYSVSLIEAVRDAIGPEAELMLEMHGRFSPSTAVRLARELAPFKPAWLEEPVPPENLKALEKVAAKVDIPVATGERIHDRIEFRELFESQAVDIIQPDVGHIGGIWETRKLAATAEAHYVLVAPHNVGGPVLTAASLQVGFTSPNFKILEHFNDFADAEIKKVVKGAPQVVDGYFELSHEPGLGVELDVDAAAEFPQQQARFDLWADGWEQRKPKGSQ
>NZ_CP041607.1|WP_060901990.1|3988360_3989365_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MSTAVVVEAPGEHRLIEHEPVRPSAGEALVRVHAVGICGSDREVYQGNRPDGYVRYPLTPGHEWSGTVEAVGAGVPESIVGRKVVGEGFRNCQVCDRCHAGETTLCTAGYEETGFTQPGAMATTLTLPARLLHVLPDDADLTAAALLEPAACIAAAALKANALPGERVAVVGTGTLGMFAIQFLKANSPAELLVVGTRPDRAALSRDFGATDFRTRDQELPDDFDVVIETAGSASAARTAASLLRRGGRLVLTGIPAPGAEGLDPTDLVVRQLEVHTVFGAPPAAWAHTVRVFGAGLLSPLPLVTHELPLAEFPQAIELVGSGDPKVGKVLLKP
>NZ_CP041607.1|WP_054233605.1|3989581_3990550_+|hypothetical-protein
MTDAAPTAARRPGEQALAALGLGAPALSPADASPHTFPGGGRWRTEVPSVEGPEALAVVLKESSRLDVPIHRISQGSGVWMLTDAEITEMVEATGERDIELCLFTGPRGTWDIGGSVRSDSRGGGLRARGHDAVAGCVEDALRATELGVKCLLVADEGVLWTLHRARAAGIIPADTTLKLSALVGPVNPASYAVYENLGADSINVPSDLTLDHLTEIRRVSAAPMDMYIEAPDDLGGYVRMYEVAELIRRGAPLYLKFGLSKAPGIYPYGHHLRDLTLNTAKERVRRGRLALDLLARHGADGDMAPLGSRLPGTLTRFNTTS
>NZ_CP041607.1|WP_054233604.1|3990682_3991804_+|sugar-ABC-transporter-substrate-binding-protein
MMIMRNRRAALTAIAGAASLALTLTACGQNSDGGSKDSSGSTKGATIGISMPTKSSERWIGDGNNVVKDLQSKGYKTKLAFGEDDPDTQVSQIENMITQGVKALIIAAIDNKSMNNVLQQAADAKIPVISYDRLILGTKNVDYYASFDNSKVGELQGNYILQKLGLADGSKKGPFNIELFAGSNDDNNTKYFFGGAMKVLQPYIDKKQLVVKSGQTALNQVTTLRWDGGTAQKRMDDILTSSYKSARVDAVLSPYDGISIGILSSLKSDDYGSKSKPLPVVTGQDAELASVKSIIAGEQTQTVYKDTRKLATVASGMVDAALKGNKPELNDTKTYDNGTKVVPAYLLQPVSVDKTNYEKELVGTGYYKDSDLK

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Crispr_ID: NZ_CP041607_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_9

4587262-4587383

Orphan

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_9

>merge|NZ_CP041607|9|4587262-4587383|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCATCGGCCCGCGGACGAAGAACCACCGGGCAGACGGGGATCCGGGGCGCAGCCCCGGCCCAGGGGCGCGGGGAACTGCGCGACCAGCCCCCA

>NZ_CP041607|9|8|4587262-4587383|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCA	TCGGCCCGCGGACGAAGAACCACCGGGCAGACGGGGATCCGGGGCGCAGCCCCGGCCC
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_097288984.1\|4588130_4588913_-\|decarboxylase	unknown	unknown	gnl\|CDD\|226004
NZ_CP041607.1\|WP_143601734.1\|4580898_4581534_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_097288986.1\|4594539_4595358_+\|ectoine/hydroxyectoine-ABC-transporter-ATP-binding-protein-EhuA	unknown	unknown	gnl\|CDD\|224051
NZ_CP041607.1\|WP_143601735.1\|4583686_4585747_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_CP041607.1\|WP_054232842.1\|4585816_4586911_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_CP041607.1\|WP_054235542.1\|4592245_4593175_+\|ectoine/hydroxyectoine-ABC-transporter-substrate-binding-protein-EhuB	unknown	unknown	gnl\|CDD\|270223
NZ_CP041607.1\|WP_143605419.1\|4581667_4583128_-\|M6-family-metalloprotease-domain-containing-protein	unknown	unknown	gnl\|CDD\|274507
NZ_CP041607.1\|WP_143601738.1\|4590183_4591587_+\|amidase	unknown	unknown	gnl\|CDD\|180437
NZ_CP041607.1\|WP_095854470.1\|4595547_4596333_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224332
NZ_CP041607.1\|WP_060901880.1\|4574217_4574814_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NZ_CP041607.1\|WP_060898408.1\|4593887_4594538_+\|ectoine/hydroxyectoine-ABC-transporter-permease-subunit-EhuD	unknown	unknown	gnl\|CDD\|132048
NZ_CP041607.1\|WP_143601736.1\|4586900_4587206_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237605
NZ_CP041607.1\|WP_143601737.1\|4587402_4588134_-\|decarboxylase	unknown	unknown	gnl\|CDD\|226004
NZ_CP041607.1\|WP_097284856.1\|4591643_4592147_-\|DUF3830-family-protein	unknown	unknown	gnl\|CDD\|315562
NZ_CP041607.1\|WP_054235581.1\|4589239_4590163_+\|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240625
NZ_CP041607.1\|WP_143601739.1\|4593171_4593891_+\|ectoine/hydroxyectoine-ABC-transporter-permease-subunit-EhuC	unknown	unknown	gnl\|CDD\|223836
NZ_CP041607.1\|WP_097284850.1\|4575072_4576071_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|379588
NZ_CP041607.1\|WP_143601733.1\|4578827_4580162_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224037
NZ_CP041607.1\|WP_054232844.1\|4580323_4580707_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143601732.1\|4577226_4578831_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_097288986.1\|4594539_4595358_+\|ectoine/hydroxyectoine-ABC-transporter-ATP-binding-protein-EhuA	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.86838e-136
NZ_CP041607.1\|WP_143601735.1\|4583686_4585747_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	5.46454e-107
NZ_CP041607.1\|WP_054232842.1\|4585816_4586911_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	6.54332e-174
NZ_CP041607.1\|WP_054235542.1\|4592245_4593175_+\|ectoine/hydroxyectoine-ABC-transporter-substrate-binding-protein-EhuB	gnl\|CDD\|270223	cd01002, PBP2_Ehub_like, Substrate binding domain of ectoine/hydroxyectoine specific ABC transport system; the type 2 periplasmic binding protein fold. This family represents the periplasmic substrate-binding component of ABC transport systems that involved in uptake of osmoprotectants (also termed compatible solutes) such as ectoine and hydroxyectoine. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.46523e-112
NZ_CP041607.1\|WP_060898408.1\|4593887_4594538_+\|ectoine/hydroxyectoine-ABC-transporter-permease-subunit-EhuD	gnl\|CDD\|132048	TIGR03003, ectoine_ehuD, ectoine/hydroxyectoine ABC transporter, permease protein EhuD. Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.	6.06793e-80
NZ_CP041607.1\|WP_143605419.1\|4581667_4583128_-\|M6-family-metalloprotease-domain-containing-protein	gnl\|CDD\|274507	TIGR03296, hypothetical_protein, M6 family metalloprotease domain. This model describes a metalloproteinase domain, with a characteristic HExxH motif. Examples of this domain are found in proteins in the family of immune inhibitor A, which cleaves antibacterial peptides, and in other, only distantly related proteases. This model is built to be broader and more inclusive than pfam05547.	6.211e-47
NZ_CP041607.1\|WP_097288984.1\|4588130_4588913_-\|decarboxylase	gnl\|CDD\|226004	COG3473, COG3473, Maleate cis-trans isomerase [Secondary metabolites biosynthesis, transport, and catabolism].	7.45734e-49
NZ_CP041607.1\|WP_060901880.1\|4574217_4574814_-\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	3.76188e-57
NZ_CP041607.1\|WP_143601736.1\|4586900_4587206_+\|hypothetical-protein	gnl\|CDD\|237605	PRK14086, dnaA, chromosomal replication initiator protein DnaA.	0.000583268
NZ_CP041607.1\|WP_143601737.1\|4587402_4588134_-\|decarboxylase	gnl\|CDD\|226004	COG3473, COG3473, Maleate cis-trans isomerase [Secondary metabolites biosynthesis, transport, and catabolism].	1.91496e-33
NZ_CP041607.1\|WP_097284856.1\|4591643_4592147_-\|DUF3830-family-protein	gnl\|CDD\|315562	pfam12903, DUF3830, Protein of unknown function (DUF3830). This is a family of bacterial and archaeal proteins, the structure for one of whose members has been characterized. Structure 3kop probably adopts a new hexameric form compared to previous structures. The putative active is near the domain interface. 3kop is most closely related, structurally to Structure 1zx8, where the potential active site is located near residues E51 and Y53 (conserved in 1zx8). Beyond the two residues above, the other residues are not conserved. Also the shape of the active site differs from that of 1zx8. Structure 1zx8 belongs to family DUF369. pfam04126, which is part of the cyclophilin-like clan.	9.41122e-82
NZ_CP041607.1\|WP_143601738.1\|4590183_4591587_+\|amidase	gnl\|CDD\|180437	PRK06169, PRK06169, putative amidase; Provisional.	0
NZ_CP041607.1\|WP_143601739.1\|4593171_4593891_+\|ectoine/hydroxyectoine-ABC-transporter-permease-subunit-EhuC	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	5.43547e-64
NZ_CP041607.1\|WP_097284850.1\|4575072_4576071_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|379588	pfam14378, PAP2_3, PAP2 superfamily.	1.70436e-65
NZ_CP041607.1\|WP_143601733.1\|4578827_4580162_+\|AAA-family-ATPase	gnl\|CDD\|224037	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair].	1.68238e-12
NZ_CP041607.1\|WP_054235581.1\|4589239_4590163_+\|D-2-hydroxyacid-dehydrogenase	gnl\|CDD\|240625	cd05300, 2-Hacid_dh_1, Putative D-isomer specific 2-hydroxyacid dehydrogenase. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomains but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric. Formate dehydrogenase (FDH) catalyzes the NAD+-dependent oxidation of formate ion to carbon dioxide with the concomitant reduction of NAD+ to NADH. FDHs of this family contain no metal ions or prosthetic groups. Catalysis occurs though direct transfer of the hydride ion to NAD+ without the stages of acid-base catalysis typically found in related dehydrogenases. FDHs are found in all methylotrophic microorganisms in energy production and in the stress responses of plants.	1.07098e-122
NZ_CP041607.1\|WP_095854470.1\|4595547_4596333_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.31306e-23

>NZ_CP041607.1|WP_143601736.1|4586900_4587206_+|hypothetical-protein
MSSTGVPPVAYVLLSSRRQQETVPAYSRHRAPARGKGLSPPPPLPVPSPGAPPPHPRQGRCAPWTPARPERPRPQTPDGLKEAGRGGRGHGLRPVLKRRMG
>NZ_CP041607.1|WP_054232842.1|4585816_4586911_-|LLM-class-flavin-dependent-oxidoreductase
MDDTDEIRGTAQGTAPVPLSVLDLVTVGAGRTATDALRTSVAISRLAESRGFHRYWVAEHHSMPGVASSSPAVILAHLAAHTTRIRLGSGGVMLPNHAPLVIAEQFGTLEAMAPGRVDLGLGRAPGTDGATAAALRRTERLHEGADDFPEQLAELTRFLDDDFPSGHPYARIHAVPGPVQSTSPGGVQSPHRPPIWLLGSSGFSARLAGVLGLPFAFAHHFSAQNTIPALDLYRESFRPSAVLDAPYALIGVSALATDDEKEARRQVRAAALNMVRLRTGRPGLVPTPEEAEAYDFSPMEREFVDSWNANVIHGTADEVRAGLDDLQKRTGADELMLTGNAHGGDVRLRSYELIADAYGLPNAD
>NZ_CP041607.1|WP_143601735.1|4583686_4585747_+|EAL-domain-containing-protein
MSGTSEGPTPTADLIRSAVTERHIDTSPRTSPRTYAEVSPSASVPAVSPPGAPPCAEASPGTYAPAETPLDTLDTPESPLDTPGSLSDTPESIPGVSESVPDAALIPSAGTSTSPGAFRAAFGAAPLPMAVVDREGLVVTANESLGALLGTGSGALVGRIAADLVDLASDARTWHAYREVLRGRQARLRCTRRLKHPDGHSLWVQVTIAPLPAQEEAVLLSIADISARRELQARLRHLQMHDPVTRLPNRTLFFERLSSALEAEAYEEGGTGRIGLCYLDLDGFKAVNDTLGHRVGDRLLASVAERLTRCADEAGYARGATPLVARLGGDEFALLVEDSTGTDQLADLAESVLKSLQAPFDLSGQRLSVSASIGVVERRAAGTSATHLMQAADTTLYWAKADGKGRWTLFDPERNAHRMTRQALSSTLRAAIERNEFALEYQPLVGMEDGGVRGVEALVRWNHPQFGTLTPNRFIGLAEEDGSIVQLGRWVLATACRQARRWQLDRPDAVPIFVSVNVAVRQVWDSDLVADVAEILAETGLAPHLLQLELTESAVMGSAGRPLQALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSVLKLDGSFVRGFQYEGPDGGAHPNPADEVIVEALIQLAHRLGLTVTAECVETASQATRLRGIGCDTGQGWLYSRPVAPDRISALLTASS
>NZ_CP041607.1|WP_143605419.1|4581667_4583128_-|M6-family-metalloprotease-domain-containing-protein
MSALAATSLITGPALAEPLFSPCALKRTGAHHSEGLDTWNADYPRPTRPLDAVLVYLSFPDSRPRTTPAELAADYFPATSQFFERASYGRFTLRPHPQRDWIRMPHTSTSYAIKRDWNAARRGAYLRDAVAAADRQVDFSRYDIVYFVADPDAPGVDSDATKVVNLDTPIEADGKEIRRVVTVFEKHPPDRLVLAHETGHVFDLPDLYHRPTDGKGEWDTYVGDWDLMGSQFGLAPDLFGWHKWKLGWLETRQVACLREHGTTRLTLEPLGSGPVTGGAGTAASGAPVSVASDAVQAGPPPAPGAGGSTSDAEGSAAGSVGSVPGPGVPGSGSGGPASGSRARTSAPALSASAPALSASRAVLPTSVPGARIFGSGRGTKLAVVRTGPDSALAFEARTSTGNDGATCTQGVLIYRIRSETDSGGGPIEVVDAHPHSESCWGESVYPPLADAPVGLGESFTVPGEKVRVEVEDRTASGAWTVKITTG
>NZ_CP041607.1|WP_143601734.1|4580898_4581534_+|hypothetical-protein
MSSTRNPASSAAPLPDRFDVCGVTPDGAAWLASAGTYPRSTLTLWEERPTAPVVLPCGTAFDIVNVPAIFGRRMLDQLWDEGPGSGPVAVHRGRTLLFSAPGTAQRLPSLLEWEEWGAGESGGSGRVDAIPPLLCHGVGDAVTVPALSPVAHLTSRWLVAPDTRHPWLPGPEILVWAAVRAARTAASAAVRISIFPPADQDAKVYDVSRRR
>NZ_CP041607.1|WP_054232844.1|4580323_4580707_+|hypothetical-protein
MAEPTPRRNEPRLRPAPLLFEPAEAAGDPEHFFDLESIDDPRALLARATELTLAFRAAADRALEFQAIAAAQLADPRRFDRLTPASIAERAEWTEDYAKKMIEFGRDLLRGAEGDGRGLGHGVGDHA
>NZ_CP041607.1|WP_143601733.1|4578827_4580162_+|AAA-family-ATPase
MTTVFDPAAAAGRATDAILDDTLHGTHRGVVVDSPPGAGKSTLVVRAALELASAGRPLMVIAQTNAQVDDLVLRLAEKNGELPVGRLHSSDPDPYDKALDDLPNVRKSTKAGDLAGLDVVISTAAKWAHVKGVEPWRHAIVDEAYQMRSDALLAVAGLFERALFVGDPGQLDPFAIVGSEQWAGLSYDPSASAVTTLLAHNPELPQHRLPVSWRLPASAAPLVSNAFYPYTPFRSGTGHGDRRLKFAVASDGSGPDRVIDEAAEAGWGLLELPARHTPRTDPEAVQAVAQVVRRLLDRGGAATSERADEPLPLTADRIAVGTAHRDQAAAVRAALADLGVADVTVDTANRLQGREFDVTVVLHPLSGRPDATAFHLETGRLCVLASRHRHACIVVCRAGVTELLDDHPSTEPVQLGVTVKFPDGWEANHAVLSHLAEHRVLWRP
>NZ_CP041607.1|WP_143601732.1|4577226_4578831_+|hypothetical-protein
MSLIATLARLEAVESGRAQPLATVRHRHLTERPLVFVPLTTAGEAGAPLGALVGTDRDAPHLLVVPQPRDRDLRFAFLAELADVVLPYVDTYADVVEAAERSETDPETGKRVKVEVELCADAPQLIVPSRAGVEFVRLLGRSTRFRRTAEQEPEAPHPAPPRVPLLGRWLTHFGERARVPGSALLLALTDVLSRHWATGQSSLEDQHLGALLAWIDPPEGASGAAGALRAELRRDARGQLVCPPAGPATDPAFDNKLLAPAIERYDRARTALAAAEDGLEADDRLGELTAAEREIRALVEQVTRPTWDAVWRGLDLLRTLPEGTHAADRWTRDRWSFTGHRDRITAGEPPQPRRDDAVTAANKLATREREQARLDAQEALDDPLVMAGRRLVGEAFAGEVTDVVMAYSESKRPSPRPLVTVRTDDRPHLGERTKVYRSLGGKPQAAEFVGYEESSEGDGLVVLRIVDKMGRGKEPETGSVPEKGDLLCFTLFEHEQRGGAKLPDPEDTPWTHGGPPGEPDAVPQPDPVTEEDIL
>NZ_CP041607.1|WP_097284850.1|4575072_4576071_+|phosphatase-PAP2-family-protein
MPQTDARRTEAAPRARLRRWTELRTAASHTRLRWWTELPLLVMVYASYSAGRLLARGDTDDAVEHGLGILRVEKALHLNAEHPLNRLFTREAWLGVPADFWYASLHYLVTPAILIWLFRSRAVRYRAARTWLMTSTLIGLIGFTLMPTCPPRLLSAGHGFVDTMAQYSSYGWWGGEASAPRGLGGMTNQYAAMPSLHVGWSLWCGVMLWRYGRTPVVRLAGIAYPLLTTIVVMGTANHYFLDAAAGAAVMGIGLLLTPYVMRLADRVRGLLGARIPWVAGASHGARSSIVSGGCQTSAGERIPRQRESRTGPEAEPGASPKDAGEGATAAAR
>NZ_CP041607.1|WP_060901880.1|4574217_4574814_-|histidine-phosphatase-family-protein
MAPRILLARHGQTEWSLSGKHTGRTDIPLLEEGRRGAKVLGERLHRAPFDGLSGVEVRTSPLARARETCELAGFGERATTWDTLMEWDYGAYEGMTPAEIQAVRPGWFIWRDGVPEGETLEQVTARADEVVAWARAEDRDVLVFAHGHILRSIGARWLGLPLDFAARIRLNPTSLSVLGWAYGEPAIEAWNDCGHLTA
>NZ_CP041607.1|WP_143601737.1|4587402_4588134_-|decarboxylase
MTALGFLYPGHSAEDDYPRIEQLLGSDVRLQLVHTDIGEDAHRVDALREMGSAARLSAGVEELRLSGAEAVVWACTSGSFVYGWEGAHEQVRALARAAGLPASSTSFAFAHAVREVGARRVAIAATYPQDVTDLFAAFLREAGVEVVSSRASGIITAAEVGTWGEGEVLALARAGDHPDADAVLLPDTALHTAAHLPALEKDLSKPVLTANQVTVWEALRLADRKVNAPTLGTLFTKEPIIQV
>NZ_CP041607.1|WP_097288984.1|4588130_4588913_-|decarboxylase
MDVSFLGGPRPQRGIGVVAPFDFALDRELWRWVPDDVSLHLTRTPFVPVEVSLDLARLVSEHETLGDAVRALNAVAPEVVAYACTSGSFVGGVAGERAMCEAMTRAGEVRSLTTSGALLEALTELAAHRIALVTPYTVSVTQSLEEYLAEAGVHVTGRAFMGLTRHIWKVPYREVVDMARRAVRGEGADALFISCTNLPTYDVIPQLEAELRIPVISANQVTMWAALRHLGTRAVGPYQRLIDQSARGGPVLPEEQEGWA
>NZ_CP041607.1|WP_054235581.1|4589239_4590163_+|D-2-hydroxyacid-dehydrogenase
MDAEPLPRLGRLTGRVRIEHADESTLAERLPRADVLLVWDFTSHAVRRAWPGEGSRPRWVHTASAGVDHLMCPELAASGTVVTNARGIFDRPIAEYVAALVLAMAKDLPRTWDLQRQREWRHRESQRVAGTRACVVGSGPIGRTIVKTLKALEVTTALVGRTARTGIHGPEELDRLMARADWVVSAAPLTEATYGMFDARRFGMMQPSARFINVGRGQLVVEDALAEALSKRWIAGAALDVFQDEPLGPDSPLWGVPGLIVSPHMSGDTVGWRDELGAQFVEMYERWEAGRPLPNVVDKKRGYVPGH
>NZ_CP041607.1|WP_143601738.1|4590183_4591587_+|amidase
MSELVELTAVQLLDGYRKGEFSPVDATRAALRRAVEIQPAVNAFVRIDADAALARAARSADRWRRGEPAGLLDGVPVSVKDILLLRGGPTLRGSKTVDPQGSWDEDAPSVARLREHGAVFLGRTTTPEFGWKGVTDSPLSGITRNPYDVTRTAGGSSGGSAAAVALGAGPLALGTDGGGSVRIPAAFCGIFGLKPTYGRVPLYPASAFGTLSHVGPMTRDAADAALMMDVISGPDARDWSALGPVDGSFVEALGGGVRGLRVAYSPSLGGQVAVQPAVAAAVRRAVERLAGLGAYVTEADPDLTDPVEAFHVLWFGGAARVAQRLGPRQRESLDPGLREICARGARFSALDYLAAVDVRMELGRRMGRFHESYDVLVTPTLPLTAFAAGVEVPPGSGHRRWTGWTPFTYPFNMTQQPAASVPVGTDGDGLPVGLQIVAARHRDDLVLRTAHALYETGAAGVAPPPGF
>NZ_CP041607.1|WP_097284856.1|4591643_4592147_-|DUF3830-family-protein
MECMADRFIEVSLVKRGIHCTAKLLDDRAPVTCAAVWDALPLGGDVYHAKYARNEIYALFPPFAKSEPPLENPTVTPIPGDLCYFAFAGTELGTKAYGYDTDVRPGTTVVDLALFYERNNLLLNGDVGWVPGIVWGQVTEGLEAMAEACNDLWRSGAQGETLSFRRA
>NZ_CP041607.1|WP_054235542.1|4592245_4593175_+|ectoine/hydroxyectoine-ABC-transporter-substrate-binding-protein-EhuB
MAPPLRNDGNDGTDAEKRSPSRRSLLAGVSALGAVGALGAAGCTRVATASDNGGDLLDRLKAQGVVRLGIAGEIPFGYIDKNGELTGEAPELAKVIFKRLGVDRVQPVPTEFGSLIPGLNSQQFDVVSAGMYINPERCQQVVFADPDYQMLDAFIVRKGNPKGLHDYKDVVAKKARFATGTGYAEIQYAVEAGYKESDILIVPDQVAGLNAVEAGRVDVFAGTALTTREVAKKSSKAESTKPFTPLVKGKPHVDGGGFAFRSAETRLRDAFNVELKKLKASGELFRILRPFGFTRAEMTDMTAKELCRG
>NZ_CP041607.1|WP_143601739.1|4593171_4593891_+|ectoine/hydroxyectoine-ABC-transporter-permease-subunit-EhuC
MTSGLWELVLKGVWVTVQLLFLSSLVAGAVSFAVGVARTSRRWIVRFLAGLYTEVFRGTSALIMIFWVYFVLPLAFGWQLVPMWAGTLALGLTYGAYGSEIVRGALNAVDPAQREGGIALSFTPWQRMRLILLPQAVPEMIPSFCNLLVELLKGTALVSIMGMGDLTFSGNLVRLALQESAEIYAYVLLIYFAIAFVITRLMRALERRLKAGIGKAPQPARATPRRAEATGVGATGGAA
>NZ_CP041607.1|WP_060898408.1|4593887_4594538_+|ectoine/hydroxyectoine-ABC-transporter-permease-subunit-EhuD
MNWDWGAVRDFMPHFWDGLLVTLQALALGSVISFALGLVWALLMRTPTRWVRWPVGVVTEFIRNTPLLVQLFFLFYVLPEWNITFSALTTGVVAIGLHYSTYTMQVYRAGIEGVPAGQWEAATALNLPLRRTWTAVILPQAIRRVVPALGNYVISMLKDTPMLMAITVLEMLGEARLYSQEHFQFTEPLTVIGVAFILISYPASLLLRALERRLVR
>NZ_CP041607.1|WP_097288986.1|4594539_4595358_+|ectoine/hydroxyectoine-ABC-transporter-ATP-binding-protein-EhuA
MPLDTSTTPADTNPAEKTDHTANPPVDGGELIRFDKVTKRFGDNTVLDGLDFRVDSGKHVTLIGPSGSGKTTILRLLMTLAKPDEGTITVAGERLHPAPEKQIREVRKKIGMVFQQFNLFPNMKVLRNITEAPVTVLGLSGDEAEARARELLEMVGLADKCDAYPSQLSGGQQQRVAIARALAMRPQVLLLDEVTSALDPELVTGVLDVLRDIAHTTDITMLCVTHEMNFARDISDQVLMFDSGHVIESGSPDRIFTDPEHERTREFLSAIL
>NZ_CP041607.1|WP_095854470.1|4595547_4596333_+|helix-turn-helix-domain-containing-protein
MAQKAQGETVALMNEPTAPYHSAQDALRVLETVARHSGGVTDVELARQTGLGTERLTALLRMLRREGYVEQVVDGAYVAGAALGRLGSAHGRDQALREKLQQTIDRLRDSVGAAIYISRYIDGEVHVTQCAEGPATPAVNEWVDFRSSAHASAVGKSLLGQLDLNARRDHLSRHKMARLTSRTITNERLLLSRLDAQPATVPVLDLQEYAIGTVCAAVPITAGSSVGCLALSLPVEHAHRLRRAADTLNRGATPVLLSLAI

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Crispr_ID: NZ_CP041607_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_10

4896318-4896439

Orphan

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCGCCCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_10

>merge|NZ_CP041607|10|4896318-4896439|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCGCCCACACGCAGCCGGACACATCCGGGCGGGACCCCTTACGGGCCGAGGGGTTCAGGGGCGCGGGGAACTGCGCGACCAGCCCCCGCCCAC

>NZ_CP041607|10|9|4896318-4896439|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCGCCCAC	ACGCAGCCGGACACATCCGGGCGGGACCCCTTACGGGCCGAGGGGTTC
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCGCCCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_097284986.1\|4903479_4905339_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|367673
NZ_CP041607.1\|WP_143601847.1\|4900100_4901351_+\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367673
NZ_CP041607.1\|WP_143601845.1\|4895815_4896043_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184256
NZ_CP041607.1\|WP_143601848.1\|4906540_4908097_+\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367673
NZ_CP041607.1\|WP_054229209.1\|4891603_4892095_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380416
NZ_CP041607.1\|WP_143601844.1\|4894792_4895806_+\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NZ_CP041607.1\|WP_097289012.1\|4897661_4898996_-\|peptidoglycan-recognition-protein	unknown	unknown	gnl\|CDD\|128941
NZ_CP041607.1\|WP_060901834.1\|4893248_4894520_+\|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl\|CDD\|183957
NZ_CP041607.1\|WP_143601846.1\|4899125_4899881_+\|TIGR03089-family-protein	unknown	unknown	gnl\|CDD\|274426
NZ_CP041607.1\|WP_054236896.1\|4909576_4910122_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|224523
NZ_CP041607.1\|WP_143605432.1\|4891178_4891388_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143601849.1\|4908170_4909457_-\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367673
NZ_CP041607.1\|WP_060901833.1\|4892157_4893117_+\|2-phospho-L-lactate-transferase	unknown	unknown	gnl\|CDD\|237443
NZ_CP041607.1\|WP_079090353.1\|4884748_4885198_+\|metallopeptidase-family-protein	unknown	unknown	gnl\|CDD\|240574
NZ_CP041607.1\|WP_003975777.1\|4890633_4890897_-\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
NZ_CP041607.1\|WP_097284985.1\|4901595_4903338_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|367673
NZ_CP041607.1\|WP_143601842.1\|4885279_4886779_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054236899.1\|4905427_4906468_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
NZ_CP041607.1\|WP_097284983.1\|4896459_4897542_-\|NDP-sugar-synthase	unknown	unknown	gnl\|CDD\|224129
NZ_CP041607.1\|WP_143601843.1\|4886775_4890447_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|224137

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_097284986.1\|4903479_4905339_+\|LCP-family-protein	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	6.44813e-40
NZ_CP041607.1\|WP_143601847.1\|4900100_4901351_+\|LytR-family-transcriptional-regulator	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	6.71021e-59
NZ_CP041607.1\|WP_143601843.1\|4886775_4890447_-\|glycosyltransferase	gnl\|CDD\|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.44382e-30
NZ_CP041607.1\|WP_143601848.1\|4906540_4908097_+\|LytR-family-transcriptional-regulator	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	7.20555e-56
NZ_CP041607.1\|WP_054229209.1\|4891603_4892095_+\|cupin-domain-containing-protein	gnl\|CDD\|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.14695e-25
NZ_CP041607.1\|WP_143601844.1\|4894792_4895806_+\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	1.98547e-22
NZ_CP041607.1\|WP_097289012.1\|4897661_4898996_-\|peptidoglycan-recognition-protein	gnl\|CDD\|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	1.48927e-49
NZ_CP041607.1\|WP_060901834.1\|4893248_4894520_+\|coenzyme-F420-0:L-glutamate-ligase	gnl\|CDD\|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
NZ_CP041607.1\|WP_143601846.1\|4899125_4899881_+\|TIGR03089-family-protein	gnl\|CDD\|274426	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein. This protein family is found, so far, only in the Actinobacteria (Streptomyces, Mycobacterium, Corynebacterium, Nocardia, Propionibacterium, etc.) and never more than one to a genome. Members show twilight-level sequence similarity to family of AMP-binding enzymes described by pfam00501.	3.47527e-77
NZ_CP041607.1\|WP_054236896.1\|4909576_4910122_+\|acyl-CoA-thioesterase	gnl\|CDD\|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	2.03492e-48
NZ_CP041607.1\|WP_143601849.1\|4908170_4909457_-\|LytR-family-transcriptional-regulator	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	6.60027e-57
NZ_CP041607.1\|WP_003975777.1\|4890633_4890897_-\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.95518e-28
NZ_CP041607.1\|WP_079090353.1\|4884748_4885198_+\|metallopeptidase-family-protein	gnl\|CDD\|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	3.86411e-28
NZ_CP041607.1\|WP_060901833.1\|4892157_4893117_+\|2-phospho-L-lactate-transferase	gnl\|CDD\|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	9.33922e-176
NZ_CP041607.1\|WP_097284985.1\|4901595_4903338_+\|LCP-family-protein	gnl\|CDD\|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	7.87498e-57
NZ_CP041607.1\|WP_143601845.1\|4895815_4896043_+\|hypothetical-protein	gnl\|CDD\|184256	PRK13700, PRK13700, conjugal transfer protein TraD; Provisional.	0.00466155
NZ_CP041607.1\|WP_054236899.1\|4905427_4906468_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	2.21918e-93
NZ_CP041607.1\|WP_097284983.1\|4896459_4897542_-\|NDP-sugar-synthase	gnl\|CDD\|224129	COG1208, GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].	8.30481e-102

>NZ_CP041607.1|WP_143601845.1|4895815_4896043_+|hypothetical-protein
MRAGSPSPPPPLPVPSPGAPPLQPHQGLRPRTPDRPERPRPQTPDGLSDTGQGGRVDRGAGGASASSLGLTRWTG
>NZ_CP041607.1|WP_143601844.1|4894792_4895806_+|DNA-3-methyladenine-glycosylase-2-family-protein
MAGRFAPRPTRTTVRGGHVVVPADASGGVPRQAVSPGRTRTWTPPWPVDLGLVLGPLRRGPGDPTFRATPDGAVWRTSRTPAGAGTLRVSARGGVVRGEAWGPGSEWLLEQLPEMLGAADDPDAFEPRHRLVAVARHRRPGLRLTRTGLVLESLIPSVLEQKVTTDEAYRAWRLLVRKFGEPAPGPAPERMSVMPEPRTWALIPSWEWHRAGVDNKRASTILRAVRVAGRLEEAVGMEPGAAQARLELVSGIGPWTSAETVQRSHGAADSVTVGDLHLPGIVGYALVGDRDADDSVMLSLLEPYAGQRHRAARLILLSGRAPARRVPRMPRGDIGRL
>NZ_CP041607.1|WP_060901834.1|4893248_4894520_+|coenzyme-F420-0:L-glutamate-ligase
MPGLPEVRQGDDLGKLIAVAEPGLVDGDVLLVTSKIVSKAEGRLVEAADREAAIDAETVRVVARRGALRIVENRQGLVMAAAGVDASNTPAGTVLLLPEDADASARAIRDELRDTLGVDVGVVITDTFGRPWRTGLTDVAIGAAGVRVLDDLRGGTDAHGNPLSATVVATADELAAAGDLVKGKASGLPVAVVRGLPHVVAEDDGEGTRAMVRGARDDMFRLGTSEAVREAVTQRRTVRAFTDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESEESRTRLLDAMRDAWIADLRRDGKSEESIAKRVRRGDVLRNAPYLVVPCLVMDGSHTYGDPRRDGAEREMFVVAVGAGVQNFLVALAGERLGSAWVSSTMFCRDVVRDVLELPEGWDPMGAVAVGHAAEEPRARPSRDAGAFVEVR
>NZ_CP041607.1|WP_060901833.1|4892157_4893117_+|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLQRAVPDADITVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEEQGWGRTDETFHLKEELAAYGVGPEWFGLGDRDFATHIVRTQMLSAGYPLSAVTEALCDRWKPGVRLIPMSDDRVETHVAVEIDGQRKVIHFQEYWVRLRASVPAEAVVPVGAEQAKPAPGVLEAIAEADVILFPPSNPVVSIGTILAVPGIREAIADAGVPVVGLSPIVGDAPVRGMADKVLAAVGVESTATAVAEHYGSGLLDGWLVDTVDASAVEQVEAAGIRCRAVPLMMSDLDTAAQMAREALTLAEEVRES
>NZ_CP041607.1|WP_054229209.1|4891603_4892095_+|cupin-domain-containing-protein
MNSDSDLQIAGDILEVPHLLQPPREHPATVSEFVGLARSIAADRSQWEHLVQYDATSRWYHRLRTGPGYEVWLLSWVPGQGSGLHDHGRSSGVLTVLEGALTERTERDTRALGAGSQRVFAPGYIHEVVNDSLEPAVSLHVYYPGLTEMPMHSAQCAPAVVTA
>NZ_CP041607.1|WP_143605432.1|4891178_4891388_-|hypothetical-protein
MRVEVSAKFASMPIRTPVHTSTVNFMSAIWEMFHLIRFICVTKGLLSSHPGHMAHNRARKPRCDPVIQM
>NZ_CP041607.1|WP_003975777.1|4890633_4890897_-|WhiB-family-transcriptional-regulator
MTELVQQLLVDDADEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYALANDERFGIWGGLSERERRRLKKAAV
>NZ_CP041607.1|WP_143601843.1|4886775_4890447_-|glycosyltransferase
MSVHSHSAVPHDAATPEFPRHVVTAVLVSHDGARWLPEALAGLLGQERPVQNAVAADTGSADDSAQLLTDALGADRVLHLARRTGFGQAVEEAIRGAGVLTPDDLPYLKRPSGWDPVTRTWRDDAYDMPELPHGEPEQWLWLLHDDSAPEPDALAQLLRVVESEQEFGREVAVVGPKLRGWYDRRALLEIGVTIANSGRRWTGLDRREQDQGQHDHVHPVLAVSTAGMLIRRDVYEELGGFDRRLPLMRDDVDLCWRAQAAGHRVLVAPEAVVRHAEAASRERRTVDCVGRTAASPHKVDKAGAVYTLLVNARTAQLPWILIRLVLGTLLRTVAYLVGKVPGQAVDEIRGLLGTLLRPERILAGRRRRGRPQVDKGELRPLFPPPGATVRATVEQVAGNFMGSDDPDATTGAGRHGGAVESGPGGDDADFLQIEQFARLKRIARNPGPMLFLVLLFVSLLACRGLLGSGSLAGGALLPAPADASELWSRYVDGWHPVGAGGTETAPPYLAIVALLSSLLLGSTGLAVTVLLVASVPLAGFAAYFASRPLVESRLLRAWASVTYAFLPAAAGALAGGRIGTAVLAILLPLIARAGVAASGLTHSSGARGSWRATWAYALLLTFTTAFTPIVWPIALVLGIALLVVRRGEITAYGPRFLAQLGTPLLVLAPWSLTLLPFGFFKEAGMPYGASAASALDLLGASPGGPGTVSGLMLIGIVLAALAALTRSARQRAVWAAWVVALVALVFAVLSNKSAWAGPATLVYGLALLAAATVGADGARARVAEQSFGWRQPVAALIAFASVAGPLLVAAGWVLGGADGPVERRDPVQVPAFVAEESGTRDQARTLVLDSDSGARVGYTLVRGSGARLGDGELAAEGGENKKLDKVVANLVAGSGADQANQLGGFAVRYVLVRKGAPREMSRVLDATPGLTRLSQQDGSALWRLDSQVSRASIVPKSGEALPIAAGPVELHTTIPSGGEGRVLRLADTADAGWTATLDGKPLTRTTVDGWAQGFELPASGGRLDVTFDAPMSHTGWLWAQGALAVVLVVLALPGRRRDVDDDLPDEPVVPAQDVTGEGRRARRLRAQAEAEQSDQAVQDEGALPPPEEEAEQTPVSVPQQQAYDEWDASTYAGAEYGTYGGEQYQGQQQYPAGTYEQQPYQADPYQAGQYDPYAYGGTAPYDPMQTYQGYDGTGQGYDAAYDPNTPPQPPHGTDSERPDGSQQ
>NZ_CP041607.1|WP_143601842.1|4885279_4886779_-|hypothetical-protein
MNRTTLSLIAGATALAAVTGFASLNAPAASGDNTAKAATQQPVERTSLLCPQPSTSEIAKTSYTSYTPVTQGTADSGKAELQAAAVESADSTSGKKAGKKTVKPALKPAEPGKPATGDGSGAEPPALVGTAEGKFAPGWTVQETTAVAVGTGRGLLGTNCTAPDTEFWFPGVSTATGRTDYVHLTNPDDSAAVVDVEMYGKDGALKSTVGEGITVQPHASEPILLSTLASGQQTDLTVHVTVRSGRVGAAVQALDDKIGGDWLAASTDPAGGLVMPGIPKDATAVRLVAFAPGDQDADLKVRLASPSGLITPAGNETLHVKAGMTAAVDLGDVTRGEAGSLVLTSTGTSAPVVAALQVVRGKGSKQEMAFIPATNPVGARATVADNSSKGTTLALSAPGQSAQVKVTASAGSEGGTAATKTYTIKGGTTQDVDAPVPAGLKGTYALTVEPVSGGPVYASRTLASAQEGVPGFTIQTLPDDRGTVAVPEADQDLSVLLKK
>NZ_CP041607.1|WP_079090353.1|4884748_4885198_+|metallopeptidase-family-protein
MDTPVPPTAAAPGPRRRDRHGRGMRGPVAPPQVPLAASRAEVFADLVQDSVERLERRWPQLADIDFMVLEVPRLDGSGEGWSDEAVPLGGTIPAHEGHPARVVVYRRPVEIRTKGRDERAALVHEVVVEQVAELLGLTPETVDPRYGED
>NZ_CP041607.1|WP_097284983.1|4896459_4897542_-|NDP-sugar-synthase
MTEAILLVGGKGTRLRPLTVNTPKPMVPAAGVPFLTHQLARARAAGVEHIVLATSYLAEVFEPYFGDGSGLGLHIEYVTEEEPLGTGGAIRNVAARLRSGPDEPVLIFNGDILTGLDIRALVATHETTGADVSLHLTRVEDPRAYGLVPTDATGRVTAFLEKPQTPEEIVTDQINAGAYVFRRSVIDTIPAGRPVSVERETFPELLATGAHLQGMVDSTYWLDLGTPQAFVRGSADLVLGRAPSPAVPGRCGDRLVLPTARVAPDAKLTGGTVVGDGARIGEGARITGSTILSGAVVEPGAVITDSLIGTRAHIGERTILSGAVIGDGAVVGPDNELREGVRVWCEAKIPAGALRFSSDQ
>NZ_CP041607.1|WP_097289012.1|4897661_4898996_-|peptidoglycan-recognition-protein
MHGILASSVGVTCAAALTLPLALSAPAQARPQAARTEPAAPGSTQSLPLVPLSGDRSLGPAAPEQGLGRRSVRTFSLVGVVWDDPDTELRGRVQVRTRATGANRWSGWQDIETHNHEHAADPDSAEGSSGRVRGSTAPLWVGDSDGVEVRVQAQVDERATAAGESPLPRGMHLELVDPGAEPAPRGALTGDGSAGAESAETYATFATNAALAPFGATEIPALSRAETEREAPALRDGAPLVKPYIGERPRIVTRRGWGADESLREGGFVYTKKVKAAFVHHTASGNNYLCSQAPSLIRSIYRYHVVSSGWRDIGYNFLVDKCGNIYEGRAGGVAKPVMGAHTLGFNNDTMGIAVLGSFGKTKPAAAAVTAIARLTAWKLGLSGADPRGKTYLKSGGGNLYRKGKNVRLNVISGHRDGFATECPGRLLYGKLGSARTAAARYQGR
>NZ_CP041607.1|WP_143601846.1|4899125_4899881_+|TIGR03089-family-protein
MNATDRTPADLLRSALAADPARPLVTFYDDATGERVELSVATFANWVAKTANLLQGELSAEPGDRVALLLPAHWQTAVWLLACSSVGVVADVGGDPGAADLVVAGPDALEAGLACSGERVALSLAPLGRRFPTPPAGYADYAVEVPSQGDRFQPYAPVDPEEAALIVAGAEHTGAEVVERARAEAASLDLTGPGSRILSALSYDTWEGLSAGLYAPLASGGSVVLCRHLERLGEDALAKRIESERVTSTVR
>NZ_CP041607.1|WP_143601847.1|4900100_4901351_+|LytR-family-transcriptional-regulator
MDSDVTDRTGPGTGASPTGAGLARRRRRRWVQYSALGVAVVVLGAVGVGLVAYEKLSRNITADEEAAAELARYEKERPTALVRDAQNILLIGSDSRSGDGNKEYGRDSGTERSDTTILLHLSANRSSATAVSLPRDLMVDVPSCRRPDGTRTGPTFAMFNSAFEVGGSACTIRTVEKLTNIRVDHHVVVDFHGFKDMVDAVDGVEVCLKEPIDDKAAKLKLPAGKVVLDGEQALGYVRARKSIGDGSDTDRMERQQRFLGALVNKVQSNDVLLNPARLYPMLDAATSSLTTDPDLASLRGLYDLVRGMRNIPTERVQFLTVPRTSYVYNANRDQLVKPAADKLFALLRADAPVAVAKDLPTDPQSGLPTTPASGHDSAFDYEEESRGNGKSRGKRPDAPTSAPTFRGNTAAEDACG
>NZ_CP041607.1|WP_097284985.1|4901595_4903338_+|LCP-family-protein
MDAQGRGRADNIDPADQWVLNPNTGEYELRLTPSAPQSGVPRPRRGSPANAGPGAGTRARRAPERESPATPGPDVPGPRRRRGAPAEPPPGRRKGRTKPKKSKAKKILLWTGGSMAFVLVAVSAAGYLYLKHLEGNVSTTDVGSAGKKGFSKDEAFNILIIGTDKRTGKGNEGYGDKGSVGHADTNILLHVSKDRTNATALSIPRDLIVDVPDCPTKQPDGSEKVVPGTQNVRFNTSLGQDGRDPGCTMRTVKAVTGISVDHFMMADFNAVKTLTSAVGGVDVCVAHAVNDKESHLKLPAGKSKVEGEQALAFVRTRHSFGNQGDLDRIKVQQQFLGSLMRKMSSSDTLTNPAKLISLAEAATKALTVDTGIGNVSTLKDVALELKKVPTKNITFTTVPVLDNPAEKVKATVVVNQSQAPAVFDAIKSDVSFTAVKQKEKKEKAEVAARLKGTRSAAADIRVDIYNGGAPGGSAQETLNWLQNTEGVPKSSQLGNAAAPLSKTTVEYSPDQADQARKLADLMGLSASALKPGKSEKNSQGLPAIVLTLGKDFKGAGVSLTTPTKAPEVDKSTADKTVCAS
>NZ_CP041607.1|WP_097284986.1|4903479_4905339_+|LCP-family-protein
MARSGVRGEGARPRVRQADDLGWDDSLYDENGDPADGGGASGGRGGDATGQGSGSTSRDSGSSGTGGDSAHADGPGAGSDRRNGRPVDKDGDDASAEPRGQGRHGGGGGRRRGGGDGGHPRRRRRILRWSASVLALLILGTAGAGYLYYQHLNNNIKKDDLNLGDEKDRAAKSKANAAGQTPLNILLIGSDARDTKENQSLGGAKDTFGGTPLADVQMLLHLSADRSNMSVISMPRDTLLKMPKCTDPDTKKVYPATVGLVMTNISLGRGGPGCTVATWEKLTKIHIDHFMKIDFSGVVSMADAIGGVPVCVDANIYSKDSQGHGSGLKLKKGTTPVKGTQALAWLRTRYGFEDNTDIGRTKAQHQYMNSMVRQLRENATISNPGKLRSLAETATKALTVDKGLGSVLKLYDLGNELKKVEPKRITMTTMPWQWAVSDSNRVEPKPVEAEQLFRLVREDIALDGKDKKKTVTAVKASTDPAAADDQIGVTVQNGTRTAALGPVGGRARTVSQLLVGKGFTKAEADSSAATAEETTVIRYPSADLQGDAQAVAKALGVPLSAVKKSTDVSGVTLVVGADWREGTAYKAKAQDNTTPESADVLNGAKTDACMHVNKDYTWS
>NZ_CP041607.1|WP_054236899.1|4905427_4906468_-|glycosyltransferase-family-2-protein
MSEKSDVRPPAVSVIMPVLNEERHLRGAVQAILAQEYDGEMEVVIAIGPSSDRTDEIAAELVREDPRVHTVPNPTGRTPAALNAAIKASRHPVVVRVDGHGMLSPNYIATAVRLLEETGAQNVGGIMHAEGENDWEHAVAAAMTSKIGVGNAAFHTGGEAAPAETVYLGVFRREALERQGGYNEEFIRAQDWELNFRIREAGGLIWFSPELKVSYRPRPSVKALAKQYKDYGRWRHVVARYHEGSINLRYLAPPTALCAIAAGVVVGAALTPWGFVIPGGYLAAIAAGSLPAGKGLPLKARLQIPVALATMHMSWGFGFLTSPKALAKKVIASRRPAVLASTEPAN
>NZ_CP041607.1|WP_143601848.1|4906540_4908097_+|LytR-family-transcriptional-regulator
MGLRCSRIPTFTPAEVSPLPTPPRSPARPQPRPQSRPQPPRSRRPPVRSTVRPPVRRKKPRWAMRVVTTISVVVLASAGIGHAVVTSLGENIARVDPFKDMKNRPAAGHGMNVLLVGTDGRDKITEEERQKYRLGGAPCHCTDTMMIVHIAANRERASVVSLPRDSYAEAPAHTDQTTGAEHGPHPIKLNAAYAEGGPQLTVRTVENMTHVKIDHYLEVDFTSFMRTVDVLGGVSICTAQPLKDSYTGLDLSAGTHTLSGGQALQYVRSRHVDGASDIGRMQRQQRFLAALIERATSSGVLLNPMKFRDVTRAVLGSVRADQGFGTDELLDLGRAMRNFSPSSSEFTTVPIGQMAYMAKGIGSTLKWDDNKAAALFQSLRDDKPLAPPHKAAHAKTVRVQVAPQQIQVQVENGTPTDGLGKRMDGALAATGFHTTGRPVNAQDRGARHSVIVYDPRWDRSAKSLAAALPGSELREVKGRGPLLKVIAGADFKEVTRVRVQDPYQAETRVVTGDQVVCT
>NZ_CP041607.1|WP_143601849.1|4908170_4909457_-|LytR-family-transcriptional-regulator
MNDWPDGWSDSNRSDRYGRGSAGAQPEGARVMRQVQRGPGSPGPRPSAPPYGGVPQQPTYDDGQGYDNGYDSGYNTGQVYGSPGGPGGPQGPGGQGGRGPRPAPNWRRRIKWIAITLVTLLVVVSVGTYFWADSKLHRDVDLSKVIDRPDAGKGTNYLIVGSDSRAGMSAEEKKKLHTGSAEGKRTDSMMILHVGDNGDTLVSLPRDSNVTIPTYKGSGSGKTFPGTGRQVKLNAAYAEDGPTLLVRTIEYNTGLHIDHYVEIGFAGFANIVDAVGGVEMTLDQGFKDKYSGADFKAGKQTLNGEQALAFVRTRHAFAASDLQRTKNQQKFLSALAHQVATPGTVLNPFKLYPTMGSGLDSLTVDKDMSLWDLGSMFWAMKGVTGGSGKSMNMPISGSTGGNLVWDKAKVKTLVDELKNDQTVTVSGN
>NZ_CP041607.1|WP_054236896.1|4909576_4910122_+|acyl-CoA-thioesterase
MTDLAPNPESDIPGKPTFASRTTLSHIMTHNDTNLLGTVHGGVIMKLVDDAAGAVAGRHSGGPAVTASMDEMVFLEPVRVGDLVHVKAQVNWTGRTSMEVGVRVLAERWNESTPPQQVGSAYLVFAAVDADGKPRRVPPVLPETERDERRYQEAQIRRTHRLARRRAIMELREKRAAEGLD

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Crispr_ID: NZ_CP041607_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_11

5280025-5280112

Orphan

Consensus_repeat	Method
CTACTTCACGAAGTCGTAGACGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_11

>merge|NZ_CP041607|11|5280025-5280112|CRISPRCasFinder
CTACTTCACGAAGTCGTAGACGGGTTGTCGTAGACGGGTTGTCGCGGACGGGTTGTCGCAGACGGCTACTTCGCGAAGTCGTAGACGG

>NZ_CP041607|11|10|5280025-5280112|CRISPRCasFinder
CTACTTCACGAAGTCGTAGACGG	GTTGTCGTAGACGGGTTGTCGCGGACGGGTTGTCGCAGACGG
CTACTTCGCGAAGTCGTAGACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_054234406.1\|5272353_5272989_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP041607.1\|WP_143602043.1\|5288168_5289062_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|235852
NZ_CP041607.1\|WP_143602041.1\|5284258_5285602_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143602028.1\|5271433_5272186_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319911
NZ_CP041607.1\|WP_143602033.1\|5277956_5278931_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182137
NZ_CP041607.1\|WP_097285183.1\|5274871_5276038_+\|acetyl-CoA-acetyltransferase	unknown	unknown	gnl\|CDD\|180434
NZ_CP041607.1\|WP_143602026.1\|5267985_5268789_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|119339
NZ_CP041607.1\|WP_097285185.1\|5277348_5278020_+\|pyridoxal-5'-phosphate-synthase	unknown	unknown	gnl\|CDD\|235555
NZ_CP041607.1\|WP_054234404.1\|5268945_5271273_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|270916
NZ_CP041607.1\|WP_060901772.1\|5294375_5295521_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173841
NZ_CP041607.1\|WP_097285181.1\|5273072_5273567_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|211538
NZ_CP041607.1\|WP_143602030.1\|5273566_5274757_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173838
NZ_CP041607.1\|WP_143602047.1\|5293315_5294365_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176240
NZ_CP041607.1\|WP_143602045.1\|5289773_5291198_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340913
NZ_CP041607.1\|WP_097285191.1\|5285869_5288095_+\|acetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|223972
NZ_CP041607.1\|WP_143602037.1\|5281065_5281689_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP041607.1\|WP_143605454.1\|5289130_5289736_+\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|214900
NZ_CP041607.1\|WP_143602039.1\|5281719_5282256_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224462
NZ_CP041607.1\|WP_060898543.1\|5282281_5282734_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143602032.1\|5276313_5277105_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_054234406.1\|5272353_5272989_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.58463e-09
NZ_CP041607.1\|WP_143602043.1\|5288168_5289062_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|235852	PRK06688, PRK06688, enoyl-CoA hydratase; Provisional.	1.94023e-75
NZ_CP041607.1\|WP_060901772.1\|5294375_5295521_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	9.69412e-125
NZ_CP041607.1\|WP_143602028.1\|5271433_5272186_-\|VOC-family-protein	gnl\|CDD\|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.34774e-27
NZ_CP041607.1\|WP_143602033.1\|5277956_5278931_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182137	PRK09906, PRK09906, DNA-binding transcriptional regulator HcaR; Provisional.	2.05546e-36
NZ_CP041607.1\|WP_097285183.1\|5274871_5276038_+\|acetyl-CoA-acetyltransferase	gnl\|CDD\|180434	PRK06158, PRK06158, thiolase; Provisional.	9.77717e-138
NZ_CP041607.1\|WP_143602026.1\|5267985_5268789_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	3.64159e-40
NZ_CP041607.1\|WP_097285185.1\|5277348_5278020_+\|pyridoxal-5'-phosphate-synthase	gnl\|CDD\|235555	PRK05679, PRK05679, pyridoxal 5'-phosphate synthase.	7.80784e-56
NZ_CP041607.1\|WP_054234404.1\|5268945_5271273_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.91918e-72
NZ_CP041607.1\|WP_097285181.1\|5273072_5273567_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	6.02519e-23
NZ_CP041607.1\|WP_143602030.1\|5273566_5274757_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	4.43543e-38
NZ_CP041607.1\|WP_143602047.1\|5293315_5294365_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176240	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase. Glutathione-dependent formaldehyde dehydrogenases (FDHs, Class III ADH) are members of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. Class III ADH are also known as glutathione-dependent formaldehyde dehydrogenase (FDH), which convert aldehydes to corresponding carboxylic acid and alcohol. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	1.33758e-157
NZ_CP041607.1\|WP_097285191.1\|5285869_5288095_+\|acetate--CoA-ligase-family-protein	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	8.93877e-100
NZ_CP041607.1\|WP_143602037.1\|5281065_5281689_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.4195e-25
NZ_CP041607.1\|WP_143602045.1\|5289773_5291198_-\|MFS-transporter	gnl\|CDD\|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.46805e-103
NZ_CP041607.1\|WP_143602039.1\|5281719_5282256_-\|hypothetical-protein	gnl\|CDD\|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	7.26596e-22
NZ_CP041607.1\|WP_143605454.1\|5289130_5289736_+\|flavin-reductase-family-protein	gnl\|CDD\|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	1.93967e-48
NZ_CP041607.1\|WP_143602032.1\|5276313_5277105_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.23475e-17

>NZ_CP041607.1|WP_143602033.1|5277956_5278931_-|LysR-family-transcriptional-regulator
MTPDSSPQQPSPPVDLDLRLVRYFTVVAEHRHFGRAATALCIAQPSLSRQIRRLEQQLGARLLDRTPQGSRLTEAGEVFLPQAKALLRSATQAAARTRAAAQPSRVTIGYTSSIIVTPAVREMRRLHPDVEVVAQHLVWNDAHAALVEHRVDVAVTRLPMRTDQLHVTILYDEPRLLLVPLDHRLAGKESVTLDDIADEPLPRVSDASWNAFWRIDPRPDGSRAPDGPLIEALEDKFEFIASGQAVGIVPADPRVDSIRPDLTTVPLHGVEPSHVVLATRADDRSRLVTAFRKCAQAHLAPPASQGQSSSLRQPPPSGEGSVRR
>NZ_CP041607.1|WP_097285185.1|5277348_5278020_+|pyridoxal-5'-phosphate-synthase
MGTDLHELLRSLRVWDVELPSFDPASAPAEPLPLFTEWFAEAVAAGQSEPHTMSLATADEDGLPDVRIVMLHGADADGWAFASHVTSRKGRQLSARPYAALGFYWPAQGRQIRLRGPVEVAPAEEGQADLHARSTGALAAALVGGQSEVLGSVEELGRASDEAWDRARREPDAPAPTWTLYRLRPEEVEFFQGDARRRHVRLVYRRTEPSPEGGGWRKELLWP
>NZ_CP041607.1|WP_143602032.1|5276313_5277105_-|methyltransferase-domain-containing-protein
MQDIVVDPVAHNRAAWDKYVQEGNEWSRPVSAEDVERARTGDWSIVLVGREPVDRSWLPTDLTGKDVLCLASGGGQQGPILAAAGARVTVFDNSPRQLGQDQMVAARDGLELRTVLGDMRDLSAFGDATFDVVFHPVSNLFVPDLAPVWRECFRVLRPGGTLLVGFLNPDVYLFDHEALDERGELIVVHKLPYSDVTQYSAEERATKFGADAALEYSHTLTDQIGGQLAAGFVLTGFAEAPHQSNASAPYMSHYFATLAVKPG
>NZ_CP041607.1|WP_097285183.1|5274871_5276038_+|acetyl-CoA-acetyltransferase
MTPGKRKVAVVGVSLSDCGRVDDATPYALHAQAARRALADAGMDRSLVDGFASAGLGTLPPVEVAEYLGLRPTWVDSTAVGGSTWEVMAAHATDAIAAGHAEAVLLVYGSTARADIKAGRRTGNLSFGARGPLQFEVPYGHTLIAKYAMAARRHMHTYGTTLEQLASVAVQARANAALNPEAMFRTPITTDDVLSGPMIADPFTKLHCCLRSDGGAAVLLAAEEYVRDCRTAPVWILGTGEHVSHTTMSEWPDFTVSPAAVSGRLAFERAGVRPDEIDVAELYDAFTYMTLVTLEDLGFCAKGEGGQFVEKGRLTVGGELPVNTDGGGLSAQHPGMRGLFLLVEAVRQLRGEAGERQVRKTGGRLPELAVASGTGGWFCSSGTVVLGR
>NZ_CP041607.1|WP_143602030.1|5273566_5274757_-|acyl-CoA-dehydrogenase
MDARFTAEQDEIRRTLRELLLKRCGPEEVRSAVRTGVGHDAGLWETLAQQLGLPGLALPTAYGGVGCSFADLALACEESGRVLAPSPLLATAALAAPLILALGTDAQRAGLLPRIAAGELTAALAVPGAGLPTALGLVGDNGGDWAGGGRAGGVQARPGEEGGWRLYGEVERVLDGHSAGLLLVAAHTGGFARARTRIFLVTEGAQGLVRMRQTSLDETRAQGRVQLRQVRAELLGEEDGDVLGALASVGDGAAAVLAVEAVGAADRALERTIAHVRQREQFGRAIGSFQAVKHRLADVYVRVQAARSAAYYAAWAAGAGGERVGGLALAQGLEALRTAAAEAIQLHGGIGFTWEHEAQLYFKRAAGDELLFGPVHRLRAYAADAARLFDGAEVAV
>NZ_CP041607.1|WP_097285181.1|5273072_5273567_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MAPGIRSRLVVRSVQKVSSTRAFARIAPHLVPAMDRAVHRLTRGRVLLSAQLLPGIVLTVRGARSGLERRTPLACMPEGEGGWILVGSNFGRPDHPAWTANLLAHPDAVISWQGEDIPVRARLLEGEERDAAWKAVLAFWPPYATYQARIDREIRLFRIVRRGT
>NZ_CP041607.1|WP_054234406.1|5272353_5272989_+|TetR/AcrR-family-transcriptional-regulator
MRTVDGRVAGRRGQATRQKLLDCLSEMLSSSPYRDVKVIDVARKAGTSPATFYQYFPDVEGAVLEIAEQMAAEGAGLTQLLEGRSWVGKAGWATAQELVDGFLEFWRKNEAILRVVDLGAAEGDKRFYKIRMKILNSVNNSLADSVSELQSKGKVDKDVNPAAIAGSLVAMLAAVASHQKGFQTWGVKQAELKPNLALLVHLGVTGKKPTK
>NZ_CP041607.1|WP_143602028.1|5271433_5272186_-|VOC-family-protein
MAVSRASDATHAYPEGVPCWVDAQLPDVEAGRRFYGELFGWTFGEGFEPHLEGVWARHHGEPVAALTPKRDGRMPTVWTVSFATPDAAALAARIQAAGGRVITAPTRLGPYGTAALATDPEGGVFGLWQAGTHPGFGERHEPGSFCWAELYARDPETVDRFYGTLFHEALFGPDASPDFGRAPVSGVFPAEMPPHFLVHFGVEDVDAVLGTVNRLGGRVQAPPFDTSYGRAAVVTDNQGASFAVLQVRGR
>NZ_CP041607.1|WP_054234404.1|5268945_5271273_-|PQQ-binding-like-beta-propeller-repeat-protein
MVDQLTQHDPRRIGPFEVLGRLGAGGMGLVYLARSASGRRVAIKTVRTELAEDQLFRVRFTREVEAARAVSGFYTAAVVDADPRAAVPWLATAYVPAPSLEEIVNECGPLPAQAVRWLAAGVAEALQSIHGAGLVHRDLKPSNVLVVEDGPRVIDFGIASGVSNTRLTMTNVAVGTPAYMSPEQAKDSRSVTGASDVFSLGSMLVFAATGHAPFHGANPVETVFMLLREGPDLEGLPDELRPLIESCMQMEATGRPNPADLQAQLAPHLFGSGSDDSGTASAWLPERAVGLIESRRGGRPPVKPQSSGGRSGGGRGPALPPPPSHAPLPVGAPDTGPVRLAGGQVPIGPGPRVADARAAAVKAPPPEAGLAASWSRPRVGVNGADPAPAVAPPPAPDSPSGWRPWRFRMSNDVWGTPSVAGDLVYVTSFEVHALDVATGRRRFKTRDVAWSMAVADGRIHASDGPTLFALNAREGADLWRLSTDAWVYSLKADRGTVITGTRGGGVQAWEASNGQKLWEITGAQTDFESPEAGPAVHDGTVYVWKDARLRALEARTGEERWSYPIGDAASCGGVPVRITSAPDGYVYISAGTRVLAVDVAGGHVRWHFEAPAVFLSPPTFVPGPAVTGGGVYLADYLGTVYALDATDGRDRWRIATEARSSIDPVLVAAGHVHVGSGKGLYTLDAVTGTPKWRFQAGGDLVGAPAVAEGRIHFGSTDHLLYTLKADDGRLRWKLATGGEITGAPVVKDGVVYACSKDRCVYALDAEKGTGTARTT
>NZ_CP041607.1|WP_143602026.1|5267985_5268789_+|enoyl-CoA-hydratase/isomerase-family-protein
MGSGRPVVNGGALRIAADKDTGVAVLTLDRPEKLNAIDEALASELSAAWRALRFDDSVRAVVLTGAGERAFSTGLDRATETPQPTSPYMVDDPLLRIGPKANDLWKPVVAAVSGMACGGAFYLLGEAEFVVADETATFFDPHTTYGMVSAYESVYAAHRMPYGEAARMALMGNAERMSARRAYDIGWVSELTPPGGALEAAVRCATVIAGYPSEGVQGTVRALWAAHEAARAHAFAQAPHLIALGNLPPARQTELFSARQPNGFRVR
>NZ_CP041607.1|WP_143602037.1|5281065_5281689_-|GNAT-family-N-acetyltransferase
MSDVHEKSLAHPFPVVDGHGLRLRPWDPESEADVATWLRGLSDPEFQRWNTPVKIVRDLDSARDSLRSRAEAVADGTAVAFCVTDAATGTTLGHIGVNDINHVIRVGIVGYWVLPEARGHQVATRALALAARYAFGAVRLHRVELGHALGHDASCRIAERCGFPYEGTLREAMFESGRHDAFRDVHLHARIATDPEPTLPPTGSGPR
>NZ_CP041607.1|WP_143602039.1|5281719_5282256_-|hypothetical-protein
MPVTGERASSEERPSGEVRAADTARASGGARFDLPEVDAFTRPYWDAAAEGRLLIRHCAGCDRAHHYPREFCPHCWSEDVRWRPASGHATLYTWSVVHRNDLPPFGERVPYVAAVVDLAEGPRMMTEVVECEDDALRIGMGLEVTFRAGVPVFRPRSGAVPPPSSSVPSPSSASKTTS
>NZ_CP041607.1|WP_060898543.1|5282281_5282734_-|hypothetical-protein
MDTIWLGGAEWLAVLRIGLGLWWLESWRHKDKKGWFERGTGIAWAADVAGKHRWNAVRSGFDVVVAPRPRTMAYVVVYAELALGLGLVAGFLTPIALVGGLLLNVLYFTLMIHDWAEQGQNAMMALISVVAFFGMGWQTWSLDSAIGLFS
>NZ_CP041607.1|WP_143602041.1|5284258_5285602_-|hypothetical-protein
MRPVSFGRALRLGACTTLAAGLVTVGLTAAPALAETESDQLWIDAPSEQTLPLGTDGGAPQGRTIDVGLYHDNGHFTVTDGKVTVDASGLAGVGEVTWPDNCAPNGATAVCSVPDVPVIGSDYSRQIHLGIRAAAGAQAGARGRITYGATATGGPDGTLTAPEDSFQTDFTLASGPDLSLAPVADVEHAQPGGAETIPFALTNKGNESAHGVTVKMTASYGVDFLNKYDACTYTRRGGDEYAPMTDATCTFDQVLAPGDSFELPAPLQLAIARRALNDRLDISVDPADGATDLASRDNYAALQIGTDNTADFSVTGAAVTGTAGQTVTAPLTFKNNGPAWFANLGSGDPAAKVRLIVPTGTTVTGVPADCVPHTLTGGYYEKRTGAPRYDCALPYWVSENTERTYAFQLRIDAAAPGTTGEVSIHPEFGDFAFDPDTTNNTAVLAVN
>NZ_CP041607.1|WP_097285191.1|5285869_5288095_+|acetate--CoA-ligase-family-protein
MLGSTHGTLTTDSRRARVIACGEQPSPVVHGRPADVDDLDVSGRPLYADAPDLDRFFRPESVAVVGASDAEGRPNTGITRQLIAWAERVGARLHPVHPTRQSVFGIPCSPSLADLPEQVDLAVLLVGDPLPVIGELAEAKVKFAVAFASGFAETGAEGAAAQAHLAAAVRHAGLRLLGPNTNLNAFEKFRDDLDGPAIALITQSGHQGRPVFAMQELGVRLSHWAPTGNEADLETADFISYFSEQPEIGAIACYVEGLKDGRSFLLAADRAARRGVPVVAVKVGRTETGARTAASHTGKLTGADTVVDAAMRQYGVIRVDGLDELQDTAALLARARAPRAEGVVVYSISGGTGAHFADLATAAGLPLPNLSAPKQAELHQWIPEYLSVTNPVDNGGHPVGDWRGRKIIDAILADPEVGVLICPITGPFPPMSDKLAQDLVDAAEQTDKLVCVVWGSPVGTEAAYRETLLGSSKVATFRTFANCITAVRAYLDHHRFVASYRSPFDEAPRTPSPSFRKTQALMRPGQQLSEHAAKQLLRAYGIRVPREQLVTSAAAAVRAASLVGYPVVMKASGAQIAHKTELGLVKIGLTSASQVRDAYRELTDIARYEGISLDGVLVCQMVERGVEMVVGVTHDQLFGPTVTVGLGGVLVEVLRDAAVRVPPFGEDQARGMLGELRGRALLEGVRGGPPVDVDALVEVVMRVQRMALELGDDIAELDINPLMVLPRGQGAVALDALVVCR
>NZ_CP041607.1|WP_143602043.1|5288168_5289062_+|enoyl-CoA-hydratase/isomerase-family-protein
MTSSPEKSAAKSADPVDSLVLHATDNHVAWITLNRPEALNAITPDQRERLIQHLSHASCDPGVRAVVITATGRGFCAGADLRGGPSTGGPQAGERVAGEQVAGEQVAGERVAGDVARMIRLGAQRLIGAVLDCEKPVIAAVNGTAAGLGAHLALACDLVLAADSAKFIEVFVRRGLVPDGGGAYLLPRLIGPQRAKELMFFGDALTAADAARLGLVNRVVPADDLEKTARDWAERLATGPTRALALTKQLVNASLDTDRTTAFAAEAAAQEINMTTADANEGVAAFTERRTPHYRGH
>NZ_CP041607.1|WP_143605454.1|5289130_5289736_+|flavin-reductase-family-protein
MAAAAVRYLRSAGASTVAGHVEALPRPELRAVGDDERAPVDQVTFRRVLGNFATGVTVVTAPGVEGEAGGEGPAGFACQSFASLSLDPPLVCFMVGRTSATWPRIARAGVFCVNVLGAHQGELCRGFAVSGADKFAGVVYDAAPVSGSPRLAGAAAWVDCTIHAVHTGGDHLIVVGRVDALGASDDDDAAAPLLFHKGRFL
>NZ_CP041607.1|WP_143602045.1|5289773_5291198_-|MFS-transporter
MTQTTDAASPGGAAAAEDPRPTEPTDFTDSTDSIVPTDSTEPTDSVEPTRASAPRVRIHRAWFVAAVTFVTIIGAAAFRSLPGLLIDPLHQEFHWSRGTIGAAVSINLALYGLTAPFAAALMDRFGIRRVVAVALMVIALGSGLTVWMTAAWQLLLCWGLLVGLGSGSMALAFAATVTNRWFTARKGLVTGILTAASASGQLIFLPLLSWIVTEHDWRPAAVTVALAALAVVPFVWLLLRDHPADVGVKPYGSAEFVPKPAPVQGAARRAVTVLLSAVRTGPFWLLAGTFAICGASTNGLVQTHFVPAAHDHGMPITAAASLLAVIGVFDVVGTVASGWFTDRFEPRRLLAVYYALRGTSLLFLPMLLAPSVHPPMIFFIVFYGLDWVATVPPTLALCREQYGEDSAIVFGWVLASHQVGAALVAFLGGVARDAFGSYDVVWYASGALCAAAALMALVIRRRPATGTPAVAALA
>NZ_CP041607.1|WP_143602047.1|5293315_5294365_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MRGVIFDGKRTQVVDDLEIRDPGPGEVQVAISAAGLCHSDLSVVDGTIPFPVPVVLGHEGAGVVEAVGAGVGHVRPGDHVALSTLANCGTCAECDRGRPTMCRKAIGMPRQPFTRGGRPLYQFASNSAFVERTVVKAVQAVRIPKDIPLPSAALIGCGVLTGVGAVLNRARVDRGDTVLVIGTGGIGLNVLQGARIAGALKIVAVDANPAKEAVARRFGATHFLTSTEAVKDILPTGADHAFECVGRVELIRQAIDLLDRHGQAVLLGVPPATAEASFLVSSMYLDKSILGCRYGSSRPQRDIALYADLYREGRLLLDELVTQTYPVEDFDKAAQDAEEGRVARAVLTF
>NZ_CP041607.1|WP_060901772.1|5294375_5295521_-|acyl-CoA-dehydrogenase
MEFGFDAEDEAFRRTAREWLTAHPVGEPVVRQDWERELGRGGWIGLGWAEDGYGNRRASLTQQVVWAEEYARSRAPARSGHIGEKLLAPTLIAHGTPEQKARFLPPVARGEELWCQGYSEPDAGSDLAGIRTAAVRDGDTYRVSGQKIWTSLAHEAHWCFVLARTEPGSSRHHGLSFLLVPMDQPGRVEVRPIRQLTGTSEFNEVFFDGAVARAEHVVGGAGNGWQVAMSLLGFERGVSTLAQQIGFAEELGRVIETAVATGAAADPVVRDHLVRQWAELRTMRWNALRTLGGSGDAGAPSVAKLLWGRWHQRLGELAVRVRGAEAATGPGDWSAVAPYELDSSQHLFLFSRADTIYGGSDEIQRTIIAERVLGLPREPKG

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Crispr_ID: NZ_CP041607_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_12

6173696-6173830

Orphan

Consensus_repeat	Method
CCCCGCCCCGAGGGGCGCGGGGAACTGCGCGCCCAGCCCCCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_12

>merge|NZ_CP041607|12|6173696-6173830|CRISPRCasFinder
CCCCGCCCCGAGGGGCGCGGGGAACTGCGCGCCCAGCCCCCACCGGGCGTCAGCCGACGAACTTGGCACGGCCGGGGGATGCGGGGCGCAGCCCCGCCCCGAGGGGCGCGGGGAACTGCGCGCCAAGCCCCCACC

>NZ_CP041607|12|11|6173696-6173830|CRISPRCasFinder
CCCCGCCCCGAGGGGCGCGGGGAACTGCGCGCCCAGCCCCCACC	GGGCGTCAGCCGACGAACTTGGCACGGCCGGGGGATGCGGGGCGCAG
CCCCGCCCCGAGGGGCGCGGGGAACTGCGCGCCAAGCCCCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143602439.1\|6182074_6182971_-\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|369561
NZ_CP041607.1\|WP_143602438.1\|6179353_6180094_-\|SLATT-domain-containing-protein	unknown	unknown	gnl\|CDD\|375613
NZ_CP041607.1\|WP_075033091.1\|6180410_6180752_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NZ_CP041607.1\|WP_143602432.1\|6163232_6164753_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP041607.1\|WP_143602437.1\|6176722_6178675_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP041607.1\|WP_143602435.1\|6170093_6171926_+\|twin-arginine-translocation-signal-domain-containing-protein	unknown	unknown	gnl\|CDD\|236505
NZ_CP041607.1\|WP_143605519.1\|6175523_6176153_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153234
NZ_CP041607.1\|WP_054231371.1\|6176149_6176638_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP041607.1\|WP_143602431.1\|6162658_6163174_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
NZ_CP041607.1\|WP_143602433.1\|6164970_6166365_+\|ethanolamine-ammonia-lyase-subunit-EutB	unknown	unknown	gnl\|CDD\|237897
NZ_CP041607.1\|WP_143602440.1\|6183012_6183480_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380345
NZ_CP041607.1\|WP_075033086.1\|6172895_6173591_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP041607.1\|WP_143602430.1\|6159995_6161621_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226089
NZ_CP041607.1\|WP_143605517.1\|6161617_6162559_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP041607.1\|WP_054231368.1\|6172086_6172737_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054231366.1\|6168438_6169722_+\|adenylosuccinate-synthase	unknown	unknown	gnl\|CDD\|234904
NZ_CP041607.1\|WP_054231375.1\|6180809_6181409_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP041607.1\|WP_143602434.1\|6166361_6167120_+\|ethanolamine-ammonia-lyase-subunit-EutC	unknown	unknown	gnl\|CDD\|235482
NZ_CP041607.1\|WP_060897796.1\|6173940_6175296_-\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|235687
NZ_CP041607.1\|WP_054231376.1\|6181401_6182061_+\|DUF5063-domain-containing-protein	unknown	unknown	gnl\|CDD\|374737

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143602439.1\|6182074_6182971_-\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.2711e-65
NZ_CP041607.1\|WP_143602438.1\|6179353_6180094_-\|SLATT-domain-containing-protein	gnl\|CDD\|375613	pfam18183, SLATT_2, SMODS and SLOG-associating 2TM effector domain 2. The SLATT domain contains two transmembrane helices. SLATT domains are generally predicted to function as pore-forming effectors in a class of conflict systems which are reliant on the production of second messenger nucleotide or nucleotide derivatives. SLATT domains are predicted to initiate cell suicide responses upon their activation. This SLATT family is the only prokaryotic SLATT family to exist as a standalone domain, with no as-yet discernable genome associations.	6.33731e-121
NZ_CP041607.1\|WP_075033091.1\|6180410_6180752_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	3.14351e-38
NZ_CP041607.1\|WP_143602432.1\|6163232_6164753_-\|amino-acid-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	1.10572e-37
NZ_CP041607.1\|WP_143602437.1\|6176722_6178675_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.52428e-78
NZ_CP041607.1\|WP_143602435.1\|6170093_6171926_+\|twin-arginine-translocation-signal-domain-containing-protein	gnl\|CDD\|236505	PRK09419, PRK09419, multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase/5'-nucleotidase.	6.16442e-132
NZ_CP041607.1\|WP_143605519.1\|6175523_6176153_+\|glutamine-amidotransferase	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	8.69514e-63
NZ_CP041607.1\|WP_054231371.1\|6176149_6176638_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	1.83496e-10
NZ_CP041607.1\|WP_143602431.1\|6162658_6163174_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	3.50965e-13
NZ_CP041607.1\|WP_143602433.1\|6164970_6166365_+\|ethanolamine-ammonia-lyase-subunit-EutB	gnl\|CDD\|237897	PRK15067, PRK15067, ethanolamine ammonia-lyase subunit EutB.	0
NZ_CP041607.1\|WP_143602440.1\|6183012_6183480_-\|cupin-domain-containing-protein	gnl\|CDD\|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	3.19847e-26
NZ_CP041607.1\|WP_075033086.1\|6172895_6173591_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.12818e-30
NZ_CP041607.1\|WP_143602430.1\|6159995_6161621_-\|ABC-transporter-permease	gnl\|CDD\|226089	COG3559, TnrB3, Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane].	9.34563e-109
NZ_CP041607.1\|WP_143605517.1\|6161617_6162559_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.67459e-86
NZ_CP041607.1\|WP_054231366.1\|6168438_6169722_+\|adenylosuccinate-synthase	gnl\|CDD\|234904	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional.	0
NZ_CP041607.1\|WP_054231375.1\|6180809_6181409_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	1.00062e-120
NZ_CP041607.1\|WP_143602434.1\|6166361_6167120_+\|ethanolamine-ammonia-lyase-subunit-EutC	gnl\|CDD\|235482	PRK05465, PRK05465, ethanolamine ammonia-lyase subunit EutC.	2.81842e-113
NZ_CP041607.1\|WP_060897796.1\|6173940_6175296_-\|aspartate-aminotransferase-family-protein	gnl\|CDD\|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NZ_CP041607.1\|WP_054231376.1\|6181401_6182061_+\|DUF5063-domain-containing-protein	gnl\|CDD\|374737	pfam16702, DUF5063, Domain of unknown function (DUF5063).	9.63162e-55

>NZ_CP041607.1|WP_075033086.1|6172895_6173591_-|GntR-family-transcriptional-regulator
MPGTGGNGAVTRSTLRQQIADALRDEVLAGRLRPGQAFTVKEIAEQYGVSATPVREALVDLSAQGLLEADQHRGFRVHEYSPDDYRGMIEARSLVTDGMFRSLLAGGMAQADDPRTLAALAGVRRRGEEAQRAATAGDLNILIGYDLRFWRELSALFGNAYLADFLHRLRVQSWVCTVQHLRRVEDLKGHLWAGHTELVDALARRDPGAAHAIVAAYNEHSLALIERLAAG
>NZ_CP041607.1|WP_054231368.1|6172086_6172737_-|hypothetical-protein
MACDLWLVPLVDVLCHTPDNPFAEELALYDKALGEAGLPPVPVYAYMPGLSGDVAPVAGFDYDALHFLRRAYLLQMCGLAVTPVDELGGDYEQLLEMFETNAQQSHLVWHYDHAGAYVPVDFPHPLANDELLAGGGPLGSSQTLLRELEFVAPSIGIDPANPPAAPQPPMAPTELEEPAAPAPYDASPFARERHVWLGLHAAATRSLAQGSMIIFS
>NZ_CP041607.1|WP_143602435.1|6170093_6171926_+|twin-arginine-translocation-signal-domain-containing-protein
MPVNPMNRREFVKKSAVTGAAVTVAGAVAATPAQAQTADHKPEKAPRTWSFSILGTTDLHSHIFDWDYYTDATYKDKAGNSVGVARVATLIKQQRAAKGENHVLLVDAGDIIQGTSLAYYYARVDPIVAAKGKRAPVHPMAVAMNHMRYDAAALGNHEFNYGIETLRKFEKQCHFPLLGANALDAKTLRPAFQPYTVKRICVPGAPDIKVGILGLTNPGIALWDKDNVSGKLAFTGLVEQAKKYVPRMRALGCDVVFLTDHSGLDGSSSYGSELPYVENASNLVAQQVPGIDAILVGHTHVEVSSYTVKNEETGKDVVLSEPYCWGMRLTVFDFELELHHGQWKVTSTKAQTLNSNTVEEDPEITRLLKADHDLVVKYVNTPVGTCTVDLSAAEACWKDVPVMDFIHQVQMATVASGLSTADAALPLISVAAPFSRTADIPAGNVTIRDVAGLYIYDNTLYGKKLTGAQLKDYLEYAAKYYHQFASGTKVDTATLTNANNFWDYMYDTAAGVEYDIDIAQAEGSRIKNLTYKGVAVADDQVFVVAVNNYRANGGSGYPHIAAADIAYSSTNEIRQLMIDYVTAKGTLDPADFAVTNWKLTQDGTPVFPAS
>NZ_CP041607.1|WP_054231366.1|6168438_6169722_+|adenylosuccinate-synthase
MPALVLLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGDQKYALHLLPSGILTPECTPVIGNGVVVDPSVLFSELNGLNERGVDTSKLLISGNAHIITPYNVTVDKVTERFLGKRKIGTTGRGIGPTYADKINRVGIRIQDLYDESILTQKVEAALEVKNQLLTKLYNRRAIEAGQVVEELLGYADRLKPYVADTVLILNQALEQDKVVLFEGGQGTLLDIDHGTYPFVTSSNPTAGGACTGSGVGPTKISRVIGILKAYTTRVGSGPFPTELLDEDGEALRRIGGERGVTTGRDRRCGWFDAVIARYATRVNGLTDFFLTKLDVLTGWEEIPVCVAYEIDGKRVEELPYSQTDFHHAKPIYENLPGWSEDITKAKSFSDLPKNAQAYVKALEDMSGAQISAIGVGPGRDETIEINSFI
>NZ_CP041607.1|WP_143602434.1|6166361_6167120_+|ethanolamine-ammonia-lyase-subunit-EutC
MTERQVMAPDSDAVLWNSLRRHTQARIGLGRAGSALPTRHRLELQAAHAAARDAVHSPFDPDVVASALAGAATIRVRSAAPDRLTYLQRPDLGRRLHDVDRAHLPRDGWDVVFVVADGLSSRAVHEHAAAVVRATTQRLPSDWRVAPVVLAEQARVALGDDIAHALGAGMAVVLIGERPGMSAADSLGAYLTYDPRPGRTTDADRNCLSNIRPPLGLSHTDAATKLATLMRRARDLGRTGVSLKDESTPALP
>NZ_CP041607.1|WP_143602433.1|6164970_6166365_+|ethanolamine-ammonia-lyase-subunit-EutB
MSTYSATLGGRTHSFAGLAGLLAAASPERSGDRLAGLAADSAQARVAARWALAEVPLARFLAEPVIPYETDDVTRLIMDSHDTAAFAPVSGLTVGELREWLLSDAADAPALAALAPGLTPEMAAAVSKLMGNADLVAVARKVQVVTAFRSTIGLPGRLATRLQPNHPTDDPAGVAAALLDGLLLGSGDAVIGINPATDSPRAVRDLLDLLDGVIDRYSIPTQSCVLCHVTTSIDLMERGAPVDLVFQSIAGTQAANASFGVTLGLLDEAYEAARSLARGTVGSNALYFETGQGSALSADAHHGVDQQTVEARAYAVARRYDPLLVNTVVGFIGPEYLYDGRQILRAALEDHFCGKLLGLPMGLDICYTNHADADDDDIATMLTMLGVAGASFVICTPGGDDIMLNYQSASYHDALYLREVLGLRPAPEFETWLGRIGLLDEGGGIRDVAGTGHPLTAIGRGLAA
>NZ_CP041607.1|WP_143602432.1|6163232_6164753_-|amino-acid-permease
MAVQEGVVPEAAGTPEAPGGAVHRLKPNAIGLLGVVFMAVATAAPITAMTGNVPFMVSAGNGIGAPASYLVAMVVLAIFAVGFTSMAKHITSTGAFYGFISYGLGRTAGLASGLLATFAYVVFEPALIGIFSTFATGTLKDQTGLDVPWWAFAVLMLAVNATGTWFGVSVAEKLLVVLLATEVTILAAMAVSVALHGGGPHGFTFGPVNPVNAFKGTSAGLGLFFAFWSWVGFESTAMYGEESRDPKKIIPKATMISVLGVGVFYVFVSWMAIIGNGESEAVTAASSSNPLALFFNPTEHYVGHWAVDVMQWLMITGSLACGMAFHNCAARYMYALGREGVLPSLQRTIGRTHPQHGSPHIAGLVQTVVSAVLIAAFWLAGKDPYTGTYVLLAILGTMAILVVQAVCSFAVLAYFRKNHPESRHWFKTFTAPLIGGLAMLGVVVLLVSNMGAAAGTESGSLVLKATPWIVALIAAGGVAYATYLKRRAPQRYALLGRTVLEETKER
>NZ_CP041607.1|WP_143602431.1|6162658_6163174_+|MarR-family-transcriptional-regulator
MAEPEALGAAGAVGRDAEAVSRFVEHFAAQLVEAGMPRMPSRVFGALLASDTGAMTSVELGEQLRISPAAVSGAVRYLAQVHMVSREREPGSRRERYRVHSDQWYEALTNREAIIKRWEDALREGVVSLGADTPAGARLAETLAFFEFMEGELESMMDRWRVHREQHFGEG
>NZ_CP041607.1|WP_143605517.1|6161617_6162559_-|ATP-binding-cassette-domain-containing-protein
MTKATTKAITVSGLHKSFGGTHALDGLDLDVEAGEVHGFLGPNGSGKSTTIRVLLGLLRGDAGAAQVLGRDPWADAVELHRRVAYVPGDVTLWRNLSGGEVIDLYGRLRGGLDRARRAELIECFELDPTKKGRTYSKGNRQKVALVAAFASDVDLLILDEPTSGLDPLMEEVFQRCVEEERDRGRTVLLSSHILSEVEELCDRVSIIRKGRTVESGTLADLRHLTRTSVTAELAGPPNGLAHLPGVHDLDIQGHRVRLQVETDKLDAVLRSLTDSGVRSLTSTPPTLEELFLRHYQDDVQDDVRVNGEGTMAR
>NZ_CP041607.1|WP_143602430.1|6159995_6161621_-|ABC-transporter-permease
MTTATTATAAVRGGVRARSSRQLAGTGTLLRFFLRRDRLMMPLWVGVIGLLVLSMPNSLKSVYGTAAERADLARQMLTNSSLRATYGPVFDDSLGGLTAWRIGGYAGLFAGIMSLLVVVRHTREEEESGRQELLSSAMVGRRAPLTAALLAALVANGVLALLIAGGLAGQGGAGALALGLGVGGVGMVFATMAAIVAQLTESARLAKGLTGGLLGAAFVLRAAGDSSTSDGSSVLTWVSPLGWLENERPFAQERWWVPALFVVAVVIQGAVAYELAGRRDVGMSFLPTRPGPARGRLGSAGALAWRLQRGAVLGWSLGFLAAGAAFGGITKGAADLVGSNAKTRQIIERMGGQSGITDAFLAAMVGMLGMVAALYVVSSVLRLHGEETSQRAEPVLANAVGRLRWAGGHLVVAFGGAALIMTLGGLGLGLGYGHELGPVLGACLVQVAAVWTLGGLAVLLYGVSPRLAPGAWGAAGVALLLGWIGPALNVPQAAMDLSPFGHLPKLPGGEMTWTPVLILTAIALALTATGLAALRRRDMST
>NZ_CP041607.1|WP_060897796.1|6173940_6175296_-|aspartate-aminotransferase-family-protein
MTPQPNPQVGAAVKAADRAHVFHSWSAQELIDPLAVAGAEGSYFWDYEGKRYLDFTSGLVFTNIGYQHPKVVAAIQEQAATLSTFAPAFAVEARSEAARLIAERTPGDLDKIFFTNGGAEAVENATRMARLHTGRPKVLSAYRSYHGATSTAINLTGDPRRWPNDSGAAGVVHFWAPFLYRSPFHSDSEQQECERALQHLEDTIAFEGPGTVAAVILETIPGTAGIMTPPPGYLAGVRALCDQYGIVFILDEVMAGFGRTGKWFAADHYDVTPDLMTFAKGVNSGYVPLGGVAISSAIAETFARRPYPGGLTYSGHPLACAAAVATINVMEEEGIVEQAARIGETVLGPGLRELAARHPSVGEVRGTGVFWALELVKDRETREPLVPYNAAGEANGPMVAFGAAAKARGLWPFINMNRTHVVPPCNVSEGEAKEGLAVLDEALSVADEYTV
>NZ_CP041607.1|WP_143605519.1|6175523_6176153_+|glutamine-amidotransferase
MNDHGGPVHLAVYDTYADWETGHTTAYLARAGREIRTVGPTREPVTTIGGLRIQPDLALDELRPEDSSLLILTGADLWDTSDDLAPFARKARAFLDAGVPVAAICGATAGLAREGLLDDRDHTSAVSFYLAATGYRGGGRCADTDAVTDGNLVTAGPTEPVAFAREVLRLLGVYEGEVLDAWYRLFHDSDASAYAVLEKASGAAEEAAR
>NZ_CP041607.1|WP_054231371.1|6176149_6176638_+|MarR-family-transcriptional-regulator
MSRERQNLLSRAALGVFRLNGQFLSVADELARPAGLTAAWWQVLGAVLPEPLPVAGIARVMGITRQSVQRVADLLVGEGLAEYLPNPAHRRAKLLSPTAAGRTAVAAIGPGHATLADRLARALGEDGFAETVRILERLSAVLDEIDGAATDVTETPGAVTEP
>NZ_CP041607.1|WP_143602437.1|6176722_6178675_+|protein-kinase
MEKLGAGEPQQIGAYRLLARLGAGGMGRVYLARSDRGRTVAVKLVREELAAQEEFRARFRQEVLAARRVGGLWTAPVLDADTEAAVPWVATGYVAGPSLQTVVGHDHGALPERSVRILAAGLAHALKDIHAAGLIHRDLKPSNVLVTIDGPRVIDFGIARALETVTDGGLTRTGALVGSPGFMAPEQVRGDRVTPACDVFCLGSVLSYAATGALPFGAANSGVHAMMFRIAQEDPDLDGVPEGLADLVRHCLRKDPAARPGLDEILERIGAEDTVVEGRSRDPWLPSALVAQLGRHAVRLLDTENPAERPAPAPAPPTRQAAAPAQEPAPGSAPAALDLSKSSAAPAPTPAPAPEVAPEHAATPPPPGGPASTDHLPTLIAGADQTPPPAAPPAAHPAYGHPQQHPSPTGPPAYGHPQGGWGAPGSYGPTPPYGPGMPTTPYGPAGVPEPEPPRRSGRSTAALIVVALVVALGAGGSVYALMQGGPAKGTDDAKASSAASKSPSSPDSSPSSPSTPSSSPSDSPSPQASQGGGAIPEGFLGTWDASIDNATGHNTRRLTIQQGAVGDTVLSLVADGPSGSSTYHCVFRAELTAAPGAGGPLVIGPSEVTGGAPISSCSPGAASEITLQSDGRLRRVNTGSGESLTYTKSG
>NZ_CP041607.1|WP_143602438.1|6179353_6180094_-|SLATT-domain-containing-protein
MSQPEMQPEGPPQDGRDDRAAGTRPGDLTGRAFPLGDWGEPAERLHELYRWVERGALDTASWYLADRVWKRRGARVLRGGAAAGAVAGAALPLLDLTGVVGGVAPWGYLALLLGVACVAGDRFFGVTSGWIRDVATAQAVQRRLQVLQFDWASESVREVLGPTEGTASEAADRCLGVLRRFSEDMTELVRVETTDWMVEFRTGAAPLGIQSSLAGVPRAEGASAGRLPLPPGTRPNMPRQRPPEPR
>NZ_CP041607.1|WP_075033091.1|6180410_6180752_+|YbaB/EbfC-family-nucleoid-associated-protein
MIPGGGQPNMQQLLQQAQKMQQDLANAQEELARTEVEGQAGGGLVTATVTGSGELRALVIDPKAVDPEDTETLADLVVAAVQAANENAQALQQQKLGPLAQGLGGSGIPGLPF
>NZ_CP041607.1|WP_054231375.1|6180809_6181409_+|recombination-protein-RecR
MYEGVVQDLIDELGRLPGVGPKSAQRIAFHILQAEPTDVRRLAQCLMEVKAKVRFCATCGNVAQEDLCNICRDPRRDLTVICVVEEPKDVVAVERTREFRGKYHVLGGAISPIEGVGPDDLRIRELLARLADGTVTELILATDPNLEGEATATYLARMIKPMGLRVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV
>NZ_CP041607.1|WP_054231376.1|6181401_6182061_+|DUF5063-domain-containing-protein
MSDATLHATSQDPDDFVVQIADQVESFIVAVTEVAKGDEPDSAVPFLLLEVSQLLLAGGRLGAHEDIVPDERYEPDLGPEPDVDDLRERLAVMLDPIDVYSEVFDPYEPRKAPVACRISDDLADVITDLRHGMAHYRAGRTTEALWWWQFSYFSNWGSTTSAALRALQSLVAHVRLNQPLDDLNGLDTDQDLGEEVLAEEAGRVMAEEIGEPLGIRSSK
>NZ_CP041607.1|WP_143602439.1|6182074_6182971_-|alpha/beta-hydrolase-fold-domain-containing-protein
MTQQQRQTLDELLRHAPFDIGGELGEQRALFHEMIASVPPPEDVTATPGRLGGIPVVTVETPGDDSSAVVLYFHGGAYALGSAGDSVGLAADVARRVGVRAVSVDYRLAPEHPFPAAVDDAVAAYRALLADGTPSSEVAFVGESAGGGLVVATLVALKEAGLPQPSSAVVFSPWADLTLSGDSLTGKADVDPALTAKGLQIRARDYLGETDPATPLASPVFADLTGLAPLLIQVGSHEILLDDAVRLAARAAKHDVAVELQVWPQVPHVFQGFAALLDDADAALTSAAAFTRAHWPAG
>NZ_CP041607.1|WP_143602440.1|6183012_6183480_-|cupin-domain-containing-protein
MSMAYLAQADQQQKLEWLDGGVFAVLLDSAATDGQLTVGRFSVAKGEAPPYHVHTREDEVFMLIKGTALVWSDDQEMELSEGGIVYLPKNVPHGYRITSDTADLLMICTPGGIEGMFRHAGRDLTTPRPEGFRIEPELLAEAADKYGQIVLGPPR

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Crispr_ID: NZ_CP041607_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_13

6516515-6516615

Orphan

Consensus_repeat	Method
TCGCGCAGTTCCCCGCGCCCCTGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_13

>merge|NZ_CP041607|13|6516515-6516615|CRISPRCasFinder
TCGCGCAGTTCCCCGCGCCCCTGAAGGGGCGCTGCCCCTCGGGGCGGTTCCTCGGCCGCGGGCCGGTGGGGGTTGATCGCGCAGTTCCCCGCGCCCCTGAA

>NZ_CP041607|13|12|6516515-6516615|CRISPRCasFinder
TCGCGCAGTTCCCCGCGCCCCTGAA	GGGGCGCTGCCCCTCGGGGCGGTTCCTCGGCCGCGGGCCGGTGGGGGTTGA
TCGCGCAGTTCCCCGCGCCCCTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143602550.1\|6513438_6513774_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197713
NZ_CP041607.1\|WP_143602553.1\|6522091_6522631_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP041607.1\|WP_143602551.1\|6513805_6514420_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371934
NZ_CP041607.1\|WP_143602548.1\|6511155_6511545_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143602554.1\|6523723_6524581_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239537
NZ_CP041607.1\|WP_054232133.1\|6523073_6523718_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP041607.1\|WP_054232132.1\|6522725_6523031_+\|DUF4229-domain-containing-protein	unknown	unknown	gnl\|CDD\|379415
NZ_CP041607.1\|WP_143602546.1\|6508064_6508523_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|238612
NZ_CP041607.1\|WP_143605545.1\|6509928_6511005_-\|abortive-phage-infection-protein	unknown	unknown	gnl\|CDD\|381626
NZ_CP041607.1\|WP_143602549.1\|6512307_6513321_-\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176189
NZ_CP041607.1\|WP_054232130.1\|6520204_6520660_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|214628
NZ_CP041607.1\|WP_143605547.1\|6511594_6512245_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP041607.1\|WP_143602547.1\|6508624_6509905_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NZ_CP041607.1\|WP_054232128.1\|6518469_6519375_+\|4-hydroxybenzoate-octaprenyltransferase	unknown	unknown	gnl\|CDD\|183814
NZ_CP041607.1\|WP_054232131.1\|6520745_6521909_+\|aminofutalosine-synthase-MqnE	unknown	unknown	gnl\|CDD\|213851
NZ_CP041607.1\|WP_060896632.1\|6514424_6515816_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP041607.1\|WP_143602552.1\|6516965_6518423_+\|menaquinone-biosynthesis-decarboxylase	unknown	unknown	gnl\|CDD\|163413
NZ_CP041607.1\|WP_054232129.1\|6519406_6520081_+\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
NZ_CP041607.1\|WP_097285776.1\|6515905_6516313_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379161
NZ_CP041607.1\|WP_143602555.1\|6524832_6526188_-\|3-oxoacyl-ACP-reductase	unknown	unknown	gnl\|CDD\|236207

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143602550.1\|6513438_6513774_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	6.81621e-08
NZ_CP041607.1\|WP_143602553.1\|6522091_6522631_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.32714e-11
NZ_CP041607.1\|WP_143602551.1\|6513805_6514420_+\|hypothetical-protein	gnl\|CDD\|371934	pfam12167, Arm-DNA-bind_2, Arm DNA-binding domain. This domain is found at the N-terminus of various phage integrases. The domain binds to DNA.	0.00967372
NZ_CP041607.1\|WP_143602554.1\|6523723_6524581_-\|hypothetical-protein	gnl\|CDD\|239537	cd03453, SAV4209_like, SAV4209_like. Similar in sequence to the Streptomyces avermitilis SAV4209 protein, with a hot dog fold that is similar to those of (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	6.29795e-11
NZ_CP041607.1\|WP_054232133.1\|6523073_6523718_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.07155e-14
NZ_CP041607.1\|WP_054232132.1\|6522725_6523031_+\|DUF4229-domain-containing-protein	gnl\|CDD\|379415	pfam14012, DUF4229, Protein of unknown function (DUF4229). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 95 and 122 amino acids in length.	2.06322e-18
NZ_CP041607.1\|WP_143602546.1\|6508064_6508523_-\|nucleoside-deaminase	gnl\|CDD\|238612	cd01285, nucleoside_deaminase, Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on the substrate. The functional enzyme is a homodimer. Cytosine deaminase catalyzes the deamination of cytosine to uracil and ammonia and is a member of the pyrimidine salvage pathway. Cytosine deaminase is found in bacteria and fungi but is not present in mammals; for this reason, the enzyme is currently of interest for antimicrobial drug design and gene therapy applications against tumors. Some members of this family are tRNA-specific adenosine deaminases that generate inosine at the first position of their anticodon (position 34) of specific tRNAs; this modification is thought to enlarge the codon recognition capacity during protein synthesis. Other members of the family are guanine deaminases which deaminate guanine to xanthine as part of the utilization of guanine as a nitrogen source.	1.78712e-39
NZ_CP041607.1\|WP_143605545.1\|6509928_6511005_-\|abortive-phage-infection-protein	gnl\|CDD\|381626	cd19608, GH113_mannanase-like, Glycoside hydrolase family 113 beta-1,4-mannanase and similar proteins. Mannan endo-1,4-beta mannosidase (E.C 3.2.1.78) randomly cleaves (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans and is also called beta-1,4-mannanase, endo-1,4-beta-mannanase, endo-beta-1,4-mannase, beta-mannanase B, beta-1, 4-mannan 4-mannanohydrolase, endo-beta-mannanase, beta-D-mannanase, 1,4-beta-D-mannan mannanohydrolase, and 4-beta-D-mannan mannanohydrolase. (1->4)-beta-linked mannans are polysaccharides with a linear polymer backbone of (1->4)-beta-linked mannose units (in plants and fungi) or alternating mannose and glucose/galactose units (glucomannan in plants and fungi, and galactomannan and galactoglucomannan in plants), such as in the hemicellulose fraction of hard- and softwoods. Complete degradation of mannan requires a series of enzymes, including beta-1,4-mannanase. According to the CAZy database beta-1,4-mannanases are grouped into various glycoside hydrolase (GH) families; GH family 113 beta-1,4-mannanases include mostly bacterial and archaeal sequences.	5.70668e-09
NZ_CP041607.1\|WP_143602549.1\|6512307_6513321_-\|zinc-binding-dehydrogenase	gnl\|CDD\|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.50907e-100
NZ_CP041607.1\|WP_054232130.1\|6520204_6520660_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	9.99453e-35
NZ_CP041607.1\|WP_143605547.1\|6511594_6512245_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.64925e-23
NZ_CP041607.1\|WP_143602547.1\|6508624_6509905_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	1.82776e-38
NZ_CP041607.1\|WP_054232128.1\|6518469_6519375_+\|4-hydroxybenzoate-octaprenyltransferase	gnl\|CDD\|183814	PRK12888, ubiA, 4-hydroxybenzoate octaprenyltransferase.	3.70696e-175
NZ_CP041607.1\|WP_054232131.1\|6520745_6521909_+\|aminofutalosine-synthase-MqnE	gnl\|CDD\|213851	TIGR03700, mena_SCO4494, putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family. Members of this protein family appear to be involved in menaquinone biosynthesis by an alternate pathway via futalosine, based on close phylogenetic correlation with known markers of the futalosine pathway, gene clustering in many organisms, and paralogy with the SCO4550 protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
NZ_CP041607.1\|WP_060896632.1\|6514424_6515816_-\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	1.39065e-54
NZ_CP041607.1\|WP_143602552.1\|6516965_6518423_+\|menaquinone-biosynthesis-decarboxylase	gnl\|CDD\|163413	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family. Members of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
NZ_CP041607.1\|WP_054232129.1\|6519406_6520081_+\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	1.72718e-67
NZ_CP041607.1\|WP_097285776.1\|6515905_6516313_-\|hypothetical-protein	gnl\|CDD\|379161	pfam13396, PLDc_N, Phospholipase_D-nuclease N-terminal. This family is often found at the very N-terminus of proteins from the phospholipase_D-nuclease family, PLDc, pfam00614. However, a large number of members are full-length within this family.	1.59412e-06
NZ_CP041607.1\|WP_143602555.1\|6524832_6526188_-\|3-oxoacyl-ACP-reductase	gnl\|CDD\|236207	PRK08261, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	0

>NZ_CP041607.1|WP_097285776.1|6515905_6516313_-|hypothetical-protein
MLRYLPFLLVLALWIYSFIDCLNTPEEEVRGLPKVVWVIVILLFGEVLVGPIAWLVAGKVGRGPTRGVTPSEWHREQRSQYVAPDDNPEFLNSLSTEPAPSKNVKDEALLKDWEADLRRREEELRRREAGEESES
>NZ_CP041607.1|WP_060896632.1|6514424_6515816_-|cytosine-permease
MTTAPAGTTAPITPEYGDRVIAVETAGSEPIPDAERHGSPLQLLWTWASPNIEFATVYIGVISVLFFGLNFWQAAAALLLGTALGALTQGVLSLDGPRFGVPQMVIGRLSFGYRGNLLPAGVNALVAGVGWFAVNSVSAAFALNTLTGLRPLPSLLLVVAVEIVIGFIGHNFVHAFEKYAFPALAVVFLVAGVWTFDHADLGASGGGGGIGGFLLAFSTAWGYAAGWNPYATDYSRYLPRTANRFRTALYPAVGLFLSVAVVSLVGAASATIAAPAGATPTAAFTGHLPSWLGDLVLLSIILGGISANALNVYSSAMSITSLGLRLPAWLGRGALVVISGVAGTAAAWASLSDAGHAYEAFLLVIAYWIGPWLGVVLVERWLRTRTPDDEPARRLGDRAFTNWPGITALLVGVAVSVPLFSNQEKYVGWVPKHWASFGDITCLVGFALSAALYALLRRAPRTG
>NZ_CP041607.1|WP_143602551.1|6513805_6514420_+|hypothetical-protein
MKKRVRGRTATGATVTGAVVLLGALLQGSSAVAQAEPAHSAPVTATCVGTRPAGSLSDRDAEDFTPLDRTLAHVERMGESARYAAVYTGLSVDEEDRATDVYRMPSASFDADLCGAAEKGVTVRLHDTDANRTDLEALADRIAADMNRWNGTFDLREVGVDEAGFVFVGVDDPTAAAPLLKKAFGARHIEVGYAEQASLLSTTG
>NZ_CP041607.1|WP_143602550.1|6513438_6513774_+|helix-turn-helix-domain-containing-protein
MTERASHRAAPEHVHPDDVPVQTALAALADPVRVTLVRELADSAEWARSCGSFDVPVGKAALSHHFSVLRGAGLVEQRDEGPKRVNRLRREEFEARFPGLLDLVLREDRAH
>NZ_CP041607.1|WP_143602549.1|6512307_6513321_-|zinc-binding-dehydrogenase
MRAVEIQEYGGPEVLRVVETEAPTPGPGQVSIDVAYTGVNFADLKARADGYRVPALPFVPGLEASGRVRALGAGVTGLAVGQQVAALTQGGAYADVVVADAVTVFPLPPGVDLRTGATLPTVLPTAYALIHTVGRLQPGETVLVQGAAGGVGTVLGQLASAAGAGAVLGVVSSEAKAEYAREHGYDEVFVTSSTTPSFAKEVREATGGRGVDLALDPVGGETLRASLDSLAPFGRLVSFGNASGAQPWQVGQPDLYPLALSVSGFSILTLAQTSPTELRALTERAFRTVVDGVVSLPVTAEFALPDAAEAHRLMGTRTSTGKLLLRAHGTDGDADLA
>NZ_CP041607.1|WP_143605547.1|6511594_6512245_-|methyltransferase-domain-containing-protein
MTSRPDATRASYDTVAVDYSEFLKAELEHKPFDRAMLAAFAEKVRGGGGGQVADLGCGPGRVTIHLESLGLDAYGIDLSPRMVAVARRSHPHLRFEVGSMTDLDIEDASLAGALAWYSTVHTPLDELPLFFREFHRILAPGGHLLLAFKVGDERVHLDHAYGHDLDLDVYRFPPERVAELLREAGLVEVARLVREADAREKTLQAFVLARRPEPSV
>NZ_CP041607.1|WP_143602548.1|6511155_6511545_-|hypothetical-protein
MRTRFRLTRDGDGFVARLTPAQAAAMREALSHVRHRDVSDLTLRLRLGIGRETVDALIERLSGGYTESHDIRFDTEELHAVHSAPTTAPTMFVSREGAFLQEPFHIRLGFYRENFDALAYGIAEAASEV
>NZ_CP041607.1|WP_143605545.1|6509928_6511005_-|abortive-phage-infection-protein
MGMAAGAGGAVVLPVGRAGATGRRPGLTYRGVVYEVTDGETPSTGWSPGRMRRDLRAIAHDLHADSVKVTGDGVERLTATAAEAAELGLNVWLEPALGDVPEREILDHLAETGRFAERLRRRGAGVHLSVGCEFVLYVPGIVPGANAQERVEHLLKGDFDPVLMARRLHRFTAKAASVGRSVFHGRLTYAAAQDEDVDWGLFDLVGVDYYGWFRDRNAYVRDLAALRRFGKPVAVMEFGCCTFEGAPEKGGMGWDVVDRGKEPPEIKGGLVRSERTQAAYLTDVLSVFESMGLYSAMAYTFVTPDAPHRPRDPRHDLDMASYGIVKTLEDRHGGWHWEPKESFRALARQYARARAHTC
>NZ_CP041607.1|WP_143602547.1|6508624_6509905_+|PucR-family-transcriptional-regulator
MPALTLRDILALDPVRGSEPELLAGEGALDRPVRWVHSSEVYEGANFLDGGELLLTNGFGLTDADEDTRRRYVRELTARGAAGLAVEVGRSLVRMPEEVVDEARRLGLPLLALHRVVPFVRITEAANRAIVARGLSGRAASMRPWGGDHTAALLADLADGQALNQPEVEARAALAGFHPGPGARLVGVSAHGARELGVVDRAARSLGGVAVLRAAFPGDVLALVAMPDDAVRAVTARRDVVRAVQEAFRTVAEAGMTVAVGHAVLAGGGWLRWSETLRAARTTLELALTVPSAEPGPTGGPVVTSSRALTLERELTRGGVDANRDRLARLVQHTLGPLLAWEAAHPSDLVRTLEIHLRHGCSPTRTAALLHIGRQSLYQRLERIESLLGLEIDDPDLLGELLAALCAQRIVRGVPATADGGLRTVA
>NZ_CP041607.1|WP_143602546.1|6508064_6508523_-|nucleoside-deaminase
MEHMDQARARMWLSTAVAEARAGLAEGGIPIGAALYGADGTLLGRGHNRRVQDGDPSMHAETSAFRAAGRQRSYRGTTMVTTLSPCWYCSGLVRQFGISRVVVGEAETFHGGHDWLAEHGVEIVLLDDPECAALMRDFIKDHPALWNEDIGE
>NZ_CP041607.1|WP_143602552.1|6516965_6518423_+|menaquinone-biosynthesis-decarboxylase
MAYDDLRSLLRALEREGDLKRIKAEVDPYLEVGEIVDRVQKAGGPALLFENVRGSAMPLAMNVFGTDRRLLKALGLKSYGEISEKIGGLLRPELPHGFVGVREAFGKLGAMTHVPPKKVKSDNAPVQEVVLHGEDVDLDALPALFTWPQDGGSFFNLGLTHTKDPESGIRNLGLYRLQRHDKRTIGMHWQIHKDSRNHYQVAARRGERLPVAIAFGCPPAVTYASTAPLPGDIDEYLFAGFIQGKRIEMVDCKTVPLQVPANAEVVLEGWLEPGEMLPEGPFGDHTGFYTPQEPFPALTIDCATMRKRPLLQSIVVGRPPTEDGPLGRATERFFLPLLKIIVPDIVDYHLPEAGGFHNCAIIAIDKKYPKHAQKVMHAVWGAHMMSLTKLIVVVDSDCDVHDLHEVAWRALGNTDYARDLTVVEGPVDHLDHASYQQFWGGKAGIDATRKWPEEGYTRDGGWPEMVLSDPETAATVDRRWKEYGL
>NZ_CP041607.1|WP_054232128.1|6518469_6519375_+|4-hydroxybenzoate-octaprenyltransferase
MTSASAALPQQPGRTKAFLRLVMIEHSVFALPFAYIAALTAMFAWDRNIHWGRLLLVTIAMVGLRTFAMAANRIIDREIDARNPRTAHRELVTGAMSVKHAWTGALVALVFFLGAAALLNPLCLALAPIAVIPMVVYPYGKRFTNFPQAILGLAQAMGPIGGWLAISGEWSWDAVILGLAVGIWIGGFDLIYACQDVDTDREIGVMSVPARFGIPAAIWGARGCHAVTTALFAWYAVATDAGAFFWLGLLIVAGAFLYEHSIVKPHDLSRLNRAFFQVNGFIGIALFVCALLDLLVRGLTV
>NZ_CP041607.1|WP_054232129.1|6519406_6520081_+|UbiX-family-flavin-prenyltransferase
MKPGQTQRRPWIVGVSGASGTPYAASVLRALLAAGESVDLVVSRASRLTLLDETGLPFRDAHWQDDLREWLARGADGKPGTFDVRIEDVRHWSAGDLAAGPSSGSYPSKGMLIVPASTACVAGVALGLSKDLLQRAASVTLKEGRKLVVAVRETPLNGQTLRHLVSLDDAGATVLPASPAFYAGATHIQDLVDFVAGRVLDAAGVEHGLYRRWEGELGGGSRAT
>NZ_CP041607.1|WP_054232130.1|6520204_6520660_+|Lrp/AsnC-family-transcriptional-regulator
MDAVDRQLIQALRENGRASYAELGRLVGLSGPSVTDRINRLEAAGVITGYRATVDSASLGLGVTALIGISLSDAADHEDVARRMRDLGEIEDCWFIAGDDSFMLKVRASDVDGLEKTIRRLSGTKGVSRTRTTIVLSTKWENRVGELPEEG
>NZ_CP041607.1|WP_054232131.1|6520745_6521909_+|aminofutalosine-synthase-MqnE
MDVGLKRELEQKVRAGERLTREDGIALYESDDLAWLGGLAHEVRTRKNGDVVHFNVNRHLNMTNVCTASCAYCSFQRKPGEKDAYTMRIEEAVRLAKAMENDNLTELHIVNGLHPNLPWRYYPRSLSELKKALPNVSLKAFTATEIHHFETISGLSASEILDELIEAGLESLTGGGAEIFDWEVRQHIVDHRTHWEDWSRIHRLAHEKGLKTPCTMLYGHIEEPRHRVDHVLRLRELQDETGGFQVFIPLRYQHDFVDMKDGKVRNRLQARTQMATGAEALKTFAVSRLLFDNVPHVKVFWVMHGVQTAQLALQHGADDMDGSVVEYKITHDADNYGTPNKLTREDLLDLIRDAGFQPVERNTRYEIIREYDGPDPARRESPQPMRV
>NZ_CP041607.1|WP_143602553.1|6522091_6522631_+|GNAT-family-N-acetyltransferase
MPLTFTLFTRDAQPTQPLPDQLLTLWTDVTNAGGAVGFVPPVTAVDIRPRAEAHLTAIAEGRTRLLAGFTADGRLAATAFLALNDHPLMRHWAWLYTVMVDPALQGRGYGADLLREAEDRARALGLEGLRLTCRGGEGLERFYASCGYKEIGRAPDALRVAPGDDRDEITMLLPLPPGD
>NZ_CP041607.1|WP_054232132.1|6522725_6523031_+|DUF4229-domain-containing-protein
MGRYTLMRLGVFAGCLVVVWGLVYLGIAPRGLGDSNYMWIVLLALVISAPISFVVLRKERDRASAQVVARVDRMKTNLEQNRSQEDGVDDATRGGVQGQTS
>NZ_CP041607.1|WP_054232133.1|6523073_6523718_+|TetR/AcrR-family-transcriptional-regulator
MGAVKNKRMPRAVREQQMLDAAVRTFGQRGYRSASMDEIADLAGVSKPLVYLYLNSKEDLFTACIRREAAALTTAVRAGVQPGLPADRQLWAGLRAFFTHTAENPDGWAVLHRQARTHGEPFAAEVAAMREELVAFVTQLIVVAAREAHRDPSLAEREVAGLAEALVGAAESLAAWANATPGVSAKQAAATLMNFAWAGLGDLMENRPWTPPQD
>NZ_CP041607.1|WP_143602554.1|6523723_6524581_-|hypothetical-protein
MTTLTLTAPPALTPLLARGALFSPLKRRPRPDAHVPPTRLVLPDVRIDLARLTTYERVCGFATGADALPVTYPHVLGFPLAMRIMASRSFPLPLLGLVHTSIEITQRQPLAASETYELGVRVAGLEPHHRGTQACVVTEARVDGTLVWESRSAYLARHRTAGEPTSTPPREPGDGTPLPVRAEWRLGGDVGRRYGAASGDRNPIHLHPLTARLFGFPRAIAHGMWTVARCLAEQGPQDAVRLHADFKAPVLLPGTVTYAADGPAFELRGTDSGRLHLTGDLQPIR
>NZ_CP041607.1|WP_143602555.1|6524832_6526188_-|3-oxoacyl-ACP-reductase
MADRYLSFTGTAPGRFLTRRLGLPQPAALHRWSPERPTLEGALLLLTAGKSTLDDMAAVLARTGLEVRTEATAQGPAGVVLDATGVADVEALAEVYAALHPVVRSVADGGRVVVLGAALDPADHHQAAAQQALEGFVRSLGKEIGRGRTVTSVRIVGAAAGSVAGAESTFRFLLSPRSAYVSGQVIEVRVAGGDGGAGEMSVPEDWARPLAGRTALVTGAARGIGRAVAETLARDGARVVCLDVPGAAAELDVVAARLDGGRALALDITSADAGARIGEALPDGLDVLVHNAGITRDRKLANMPAERWGSVLDVNLASVLRTTDVLLGDGVVRRGGRIVATASIAGIAGNVGQTNYAASKAGVVGFVRALAPRGWGEHGVTVNAVAPGFIETKMTAAVPLFVREAGRRMNSLGQGGLPVDVAETIAWLAGPGSWGVNGQVVRVCGQSLLGA

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Crispr_ID: NZ_CP041607_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_14

7390923-7391061

Orphan

Consensus_repeat	Method
GGGGCGGAGCCCCGCCTGAGGGGCGCGGGGAACTGCGCGTCAGCCCCCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_14

>merge|NZ_CP041607|14|7390923-7391061|CRISPRCasFinder
GGGGCGGAGCCCCGCCTGAGGGGCGCGGGGAACTGCGCGTCAGCCCCCACCTACCCGCGGTCGAGTGTGTGCGGGCGGGTGGGGATTCGGGGCGGAGCCCCGCCTGAGGGGCGCGGGGAACTGCGCGATCAGCCCCCAC

>NZ_CP041607|14|13|7390923-7391061|CRISPRCasFinder
GGGGCGGAGCCCCGCCTGAGGGGCGCGGGGAACTGCGCGTCAGCCCCCACC	TACCCGCGGTCGAGTGTGTGCGGGCGGGTGGGGATTC
GGGGCGGAGCCCCGCCTGAGGGGCGCGGGGAACTGCGCGATCAGCCCCCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_082417802.1\|7394302_7395253_-\|DUF4097-family-beta-strand-repeat-protein	unknown	unknown	gnl\|CDD\|226123
NZ_CP041607.1\|WP_143602867.1\|7396628_7400456_-\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	unknown	unknown	gnl\|CDD\|237030
NZ_CP041607.1\|WP_054236710.1\|7401928_7402666_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP041607.1\|WP_143602864.1\|7385344_7386133_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP041607.1\|WP_097286206.1\|7386231_7387026_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP041607.1\|WP_010984411.1\|7392355_7392565_+\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP041607.1\|WP_005312030.1\|7396268_7396451_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_097286208.1\|7392564_7393131_+\|peptidase	unknown	unknown	gnl\|CDD\|274529
NZ_CP041607.1\|WP_054228111.1\|7389499_7390774_+\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|223358
NZ_CP041607.1\|WP_054236711.1\|7400738_7401842_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP041607.1\|WP_054228113.1\|7387022_7387961_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP041607.1\|WP_143605643.1\|7381491_7382364_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319
NZ_CP041607.1\|WP_143602866.1\|7395411_7396239_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054228112.1\|7387999_7388956_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270225
NZ_CP041607.1\|WP_054228272.1\|7384266_7384701_+\|nickel-type-superoxide-dismutase-maturation-protease	unknown	unknown	gnl\|CDD\|274282
NZ_CP041607.1\|WP_143602865.1\|7393236_7394301_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367559
NZ_CP041607.1\|WP_097286207.1\|7391245_7392211_+\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176227
NZ_CP041607.1\|WP_143602863.1\|7384604_7385234_-\|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|378696
NZ_CP041607.1\|WP_004983535.1\|7383726_7384122_-\|superoxide-dismutase,-Ni	unknown	unknown	gnl\|CDD\|131800
NZ_CP041607.1\|WP_143602862.1\|7382532_7383486_+\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176228

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_082417802.1\|7394302_7395253_-\|DUF4097-family-beta-strand-repeat-protein	gnl\|CDD\|226123	COG3595, COG3595, Uncharacterized conserved protein [Function unknown].	7.37694e-11
NZ_CP041607.1\|WP_143602867.1\|7396628_7400456_-\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
NZ_CP041607.1\|WP_054236710.1\|7401928_7402666_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.63381e-82
NZ_CP041607.1\|WP_143602864.1\|7385344_7386133_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.12981e-16
NZ_CP041607.1\|WP_097286206.1\|7386231_7387026_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	9.64581e-157
NZ_CP041607.1\|WP_010984411.1\|7392355_7392565_+\|HTH-domain-containing-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	0.000634141
NZ_CP041607.1\|WP_097286208.1\|7392564_7393131_+\|peptidase	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0.000124104
NZ_CP041607.1\|WP_054228111.1\|7389499_7390774_+\|NADP-dependent-malic-enzyme	gnl\|CDD\|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	3.87999e-175
NZ_CP041607.1\|WP_054236711.1\|7400738_7401842_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.13962e-48
NZ_CP041607.1\|WP_054228113.1\|7387022_7387961_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.86866e-78
NZ_CP041607.1\|WP_143605643.1\|7381491_7382364_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	5.0943e-41
NZ_CP041607.1\|WP_054228112.1\|7387999_7388956_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.63674e-82
NZ_CP041607.1\|WP_054228272.1\|7384266_7384701_+\|nickel-type-superoxide-dismutase-maturation-protease	gnl\|CDD\|274282	TIGR02754, putative_signal_peptidase, nickel-type superoxide dismutase maturation protease. Members of this protein family are apparent proteases encoded adjacent to the genes for a nickel-type superoxide dismutase. This family belongs to the same larger family (see pfam00717) as signal peptidase I, an unusual serine protease suggested to have a Ser/Lys catalytic dyad. [Cellular processes, Detoxification, Protein fate, Protein modification and repair].	5.20123e-25
NZ_CP041607.1\|WP_143602865.1\|7393236_7394301_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	1.27171e-21
NZ_CP041607.1\|WP_097286207.1\|7391245_7392211_+\|zinc-binding-dehydrogenase	gnl\|CDD\|176227	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family. This group contains proteins related to the zinc-dependent alcohol dehydrogenases. However, while the group has structural zinc site characteristic of these enzymes, it lacks the consensus site for a catalytic zinc. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	3.13613e-102
NZ_CP041607.1\|WP_143602863.1\|7384604_7385234_-\|CGNR-zinc-finger-domain-containing-protein	gnl\|CDD\|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	3.88932e-13
NZ_CP041607.1\|WP_004983535.1\|7383726_7384122_-\|superoxide-dismutase,-Ni	gnl\|CDD\|131800	TIGR02753, Superoxide_dismutase, superoxide dismutase, Ni. This superoxide dismutase uses nickel, rather than iron, manganese, copper, or zinc. Its gene is always accompanied by a gene for a required protease.	1.91906e-65
NZ_CP041607.1\|WP_143602862.1\|7382532_7383486_+\|zinc-binding-dehydrogenase	gnl\|CDD\|176228	cd08267, MDR1, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	2.26147e-87

>NZ_CP041607.1|WP_054228111.1|7389499_7390774_+|NADP-dependent-malic-enzyme
MAAEIVNPRSDSSTGLEGDVEPVNSAGSVDTVGSDGSVDSLDFDPAFALHRGGKMAVQATVPVRDKDDLSLAYTPGVAKVCSAIAEQPELVHDYTWKSSVVAVVTDGTAVLGLGDIGPEASLPVMEGKAILFKQFGGVDAVPIALDCTGVDEIVETVVRLAPSFGGVNLEDISAPRCFEIERKLQERLDIPVFHDDQHGTAIVTLAALRNAAKLTGRTLGDLRAVISGAGAAGVAIAKFLLEAGIGDVAVADRKGIVSADRDDLTDVKRELAGITNKAGLTGSLESALAGADVFIGVSGGTVPEPAVASMAEGAFVFAMANPNPEVHPEIAHKYAAVVATGRSDFPNQINNVLAFPGIFAGALQVRASRITEGMKIAAAEALAAVVGDDLAADYVIPSPFDERVAPAVTAAVAAAARAEGVARR
>NZ_CP041607.1|WP_054228112.1|7387999_7388956_-|ABC-transporter-substrate-binding-protein
MTASTTRRTTAAQSRIAAVGAIAVAGALVLTGCGDQTKKDSNSSSSSAASAPLASKLPASIRDAGVIKVGSDIAYAPVEFKDSSGKTVGIDPDLADAMGKQLGVKFDFQNGTFDTLITGLRSKRYDMAMSAMTDTADRQNGVDADTGKKVGEGVDFVDYFTAGVSIYTPKGKTQNIKTWADLCGKKIAVQRGTVSEDLAKSESKKCTGGKKIAIESYDNDQQAQTRVRAGGADAGSSDFPVAAYAVKTSGGGKDFELVGEQVEAAPYGIAVAKSNTQLRDALQAALDAIIKNGEYDKVIAKWGVEAGAVKTAAVNGGK
>NZ_CP041607.1|WP_054228113.1|7387022_7387961_-|amino-acid-ABC-transporter-permease
MTVDIDKTAGPEDTPPAGPEAIKAIPVRHYGRYLSAVIAIAVLVAIIYAFGQGKINWHAVPDYFFDHRIIKGVGQTLLLTVLSMAIGILGGILLAVMRLSKNPVTSSIAWFYIWFFRGTPVLVQLFVWFNLGLVFEYINLGPIYKDYWSSFMTPFLTALLGLGLNEAAYMAEICRAGLLSVDEGQTEASHALGMSHGKTLRRIIIPQAMRVIVPPTGNEVINMLKTTSLVSAVQYYELLRYAQDIGQTSGAPVEMLFLAAAWYLIMTSVLSVGQYYVERYYARGSSRQLPPTPWQKIKANLTSLSSRKGATA
>NZ_CP041607.1|WP_097286206.1|7386231_7387026_-|amino-acid-ABC-transporter-ATP-binding-protein
MTEKETGKDISGTPMVKSEGVHKSFGAVEVLKGIDLEVKPGEVFCLIGPSGSGKSTFLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPHMTALENVMEAPVQVKSISRTQARARAEQLLERVGLADKAASYPSQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMIVVTHEMGFAREVGDSLVFMDGGVVVESGHPRDVLTNPQHERTQSFLSKVL
>NZ_CP041607.1|WP_143602864.1|7385344_7386133_+|methyltransferase-domain-containing-protein
MTVGTGIDSDEIHGNGTDWHAWQESWDRQQEWYMPDREERFRVMLDMVEALCGPEPRVLDLACGTGTITARLLDRFPKATSTGVDLDPALLTIAEGTFAGDARVSFVTADLKDPHWATRLPYDSYDAVLTATALHWLHSEPLAVLYGQVAQLVRDGGVFMNADHMIDESTPRINEAERAQRHARMDQARARGVLDWAAWWELAAQDPALAAPTARRFEIYGEHADGDMPSVDWHTRVLREKGFGEARAVWRSPSDALVLAVK
>NZ_CP041607.1|WP_143602863.1|7384604_7385234_-|CGNR-zinc-finger-domain-containing-protein
MELAYYSDYAVRLVNTEEPTRGKDSLTSVEAVRDLFEGNSSAARRATDADVTRFRSVRARLRAVFEAADGGDETLSVDLLNSLLLEFPVSPQISGHDHRDDDGRPLWHMHLADHPSNATAGYAAIAAMGLAFHLTAYGVDRLGLCEAAPCRNAYLDTSTNRSRRYCSDRCATRANVAAYRARKRLEADRSESTGLAAPRAQRTTASGER
>NZ_CP041607.1|WP_054228272.1|7384266_7384701_+|nickel-type-superoxide-dismutase-maturation-protease
MPELSQETERGRAVLPFGAAEVTGPSMVPTLQHGDRLVVQYGARVGPGDVVVLRHPFQQDLLVVKRIAERREGGWWVLGDNAYAGGDSTDYGTVPEDLVLGKVRFRYRPHLPGQRSPLAVVRWALGAARPVLSDRSASRRLRAR
>NZ_CP041607.1|WP_004983535.1|7383726_7384122_-|superoxide-dismutase,-Ni
MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAGNDDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKASTDPATGQKALDYIAQIDKIFWETKKA
>NZ_CP041607.1|WP_143602862.1|7382532_7383486_+|zinc-binding-dehydrogenase
MKAAQITSYGDAVDVLRINDVDRPAPGAGEVLVRVEASSVNGHDVIVRSGEMKIVSGRRFPLGTGLDFAGVVTGSGTGVEGLRVGERVWGTVHPRQRHIIGGAAEYVVVPADRLAPAPTALSAAEAASLVVAGATALIAVRDTVRLAPGEKVLVRGAAGGVGTAAVQLAHALGCHVTALARARHAPALTDLGADEVLDHGSTTSDRIGPFDVVVDTVGTELNCYRSRLAKGGRMVTVGLSAPALAAIAVSSVYGARRVRTFSANPDATVLRALADHVTSGALRPVVNSVHPLADIAAAHQAFERGGVVGKHVVAVSE
>NZ_CP041607.1|WP_143605643.1|7381491_7382364_-|helix-turn-helix-domain-containing-protein
MSDDPRHELGEFLRTRRTRLRPQDVGLEPGPRRRVAGLRREELALLAGVSSDYYQRMEQGRDVRPSEQVLDALARALNFTAEETRHLHSLAAAARTPARRPRHHAPEEVPPTTLRLLRTMTSPSVVVGRFLDVLAWNPLAGALLGEFTQRPRSERNLLSLLLHPEADRTCPERAATVAELVAMLRTQVAAEPGHPRAVELVGELAVHSDEFAGLWARHDVAETTRGRMRVRHPLVGELNLDWDAYPMPDATGPVLIAFTAEEGGPDAERLQLLAGLLVAPGPAAAPPPRP
>NZ_CP041607.1|WP_097286207.1|7391245_7392211_+|zinc-binding-dehydrogenase
MFAAYAARIDRDQPLTGLELGERPAPEPRPGWTTVNVRAASLNHHDLWSLRGVGLAEDKLPMILGCDAAGVDEDGNEVVLHSVIGQTGHGVGPKEPRSILTERYQGTFAEQVSVPTWNVIPKPKELSFEEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIVLGKAAGLRVFATSRDEAKRKRAVELGAVEALESGARLPQRVDAVIETVGAATWSHSVKSLRPGGTLVISGATSGDRPSHAELTRIFFLELKVVGSTMGTKDELEDLLSFCAATGVRPVIDEVLPLDRAREGFERLAAGDQFGKIVLTVG
>NZ_CP041607.1|WP_010984411.1|7392355_7392565_+|HTH-domain-containing-protein
MTEATDLAERAGDRDPRIGLRAVSALRRLLEQLEAVQVRSARNQGWSWQEIAAELGVSRQAVHKKYGRQ
>NZ_CP041607.1|WP_097286208.1|7392564_7393131_+|peptidase
MFERFTKDARAVVAGAVGHAERTGAEAVDEEHMLLALLDREGSRGSFALASLGAAGRRDSMERALAEARRRGGLSRADTEALSGLGIDLSEIVSRVEEAHGVGALGSGNGGGGGRRSRRRPFAPGAKDVLTRSLRAALARHDRHIGDEHLLMALTARPGVPAEVLADHGVTYEAVTRVLYGGGEAKAG
>NZ_CP041607.1|WP_143602865.1|7393236_7394301_-|PadR-family-transcriptional-regulator
MPPVFAHGRLRLYLLKLLDEAPRHGYEVIRLLEERFQGLYAPSAGTVYPRLAKLEAEGLVTHTTEGGRKVYAITDAGRAELADRSGELADLELEIRDSVAELAAEIRADVRGAAGDLRREMRAAATEARRTGKGGTGTGSGEHEGPAGEFGDFGDSRDKESWRVAKEEMRRVKQEWKEQNRRAKDESRRARDEAQRARRQAKEAQEEMQRMAKRVQEQVQDRFARGDWPNGVREGLSELAKEFGDFGKTFGKDFGKDFGFGRAGAAATGSAKPEYAEYTDTPEDFPADYAPSWAHEDSTGDPARDLERLLDRFRDDIRDAARDHGVTEDQLRSARRHLSTAAAHIGAALRTSKS
>NZ_CP041607.1|WP_082417802.1|7394302_7395253_-|DUF4097-family-beta-strand-repeat-protein
MARRVQITSSPDARPVWSGRWEVCTMSEWSVAEPRKLTFDDPVTALHVRVVNGTVNVVGTDEGSARLEVSELEGPPLLVTQQDGTLTVAYEDLPWKGFLKWLDRKGWRRSAVVTLAVPAGTSVEVGVVGAAAVVSGMENRVAVKGVTGDTTLVRIAGPVRVETVSGSLEAQAVTGDLRFNSVSGDLTVVEASGCSVRAESVSGSMIVDLDPRGTPTDVQLSNVSGEIAIRLPHPADAEVEANTASGTVSSAFEDLRVSGQWGAKKITGRLGAGNGKLKAMTVSGSIAMLRRPTAEDEPHEDGSSASPETPTDKKVL
>NZ_CP041607.1|WP_143602866.1|7395411_7396239_+|hypothetical-protein
MPTTPDPSQAKAAGALLLCRAGHESVGLAAQLLRERMLLTGAGPEWSVLVPEGEPWLHGAEPVDRVVTGWATALAVSAPWPVLALWWDADRSGLTLAAGFRRTVGYEWLANGTPVGEDEAMRTFAARLGLDPVLDMQALDPLTRPVSGADARARLRGLLAVLTRAGVLLPAGLGPGEPADRLLEVARTQPGAEQIEWNGWRAAVRAELEAPEGAGGGSWLRGRRARVLATGQLAAGLPLTVWGVRRHSAGWIVAGTLLMLHGALGLAYDRLRAFD
>NZ_CP041607.1|WP_005312030.1|7396268_7396451_-|hypothetical-protein
MYFTDRGIEELEKRRGEEEVTFEWLAEQLRTFVDLNPDFEVPVERLATWLARLDDEDDEE
>NZ_CP041607.1|WP_143602867.1|7396628_7400456_-|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit
MSPQSPSNSSISTDDQAAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPGAPAASASAGTAAAGAAGTTTPSATPQAAPAAPAAPAAPAAPAAPAQAAPAPVQAAAPAAAPAAPKPAAAAPAPVKAAPAAAKPKAEPATEAPEGPEYVTLRGPAGAVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWHYAEKDGKPTLVKPAHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGENGFFDEIFEALRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLETVDPVIEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVREAVSQGAEVQISDAQAQFPVAVQTAVSQEVVKRIAESQVNIPDNVTVHPRLLPQLQRRAAMIEDGTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRGTFGQRHAVLIDRVTGEDFTPLQYLSDDQARYNVYDSLLSEYAVMGFEYGYSLARPDALVMWEAQFGDFVNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAQPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGAFRPVIGDDSVEAAAVRRVVFCAGKLYYDLEAERQKRGVTDTAIIRIERLYPLAGAELQAEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADIPGAERLRRISRPAGSSPAVGSAKRHQAEQEQLVREVFEA
>NZ_CP041607.1|WP_054236711.1|7400738_7401842_-|HAMP-domain-containing-histidine-kinase
MSGPGEPGRGEGFWGSVRPFSIKTKLGALVVISVLITTGLSMIAVHTKTELRFITVFSMIATLLITQFVAHSLTAPLDEMNTVARSISHGDYTRRVRDDRRDELGDLAQTINLMADELEAQDRQRKELVANVSHELRTPIAGLRAVLENVVDGVSAADPETMRTALKQTERLGRLVETLLDLSRLDNGVVPLRRRRFEVWPYLSGVLKEANMVASVRAGIASGSGSHTRTDVHLHLDVSPPELTAHADPERIHQVVANLIDNAVKHSPPHGRVTVKARRGDYPESLALEVLDEGPGIPQSEWHRVFERFNRGGVPSPHGPGSDGGTGLGLAIARWAVDLHGGRIGVAESQRGCRIQVILPGLPSLPS
>NZ_CP041607.1|WP_054236710.1|7401928_7402666_-|response-regulator-transcription-factor
MEQTHTSHNGTAATPGAQRRVLVVEDDPTIVDAIAARLRAEGFLVQTAGDGPAAVDTAEAWQPDLLILDIMLPGFDGLEVCRRVQAQRPVPVLMLTARDDETDMLVGLGVGADDYMTKPFSMRELAARVHVLLRRVERAVVAASTPRSGILRLGELEIDHAQRRVRVRSEDVHLTPTEFDLLVCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKALRRKIGAERIRTVHGVGYALETPTP

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Crispr_ID: NZ_CP041607_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_15

7760680-7760792

Orphan

Consensus_repeat	Method
GGGGCATCGGCCTTCGGCCTTGTCCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_15

>merge|NZ_CP041607|15|7760680-7760792|CRISPRCasFinder
GGGGCATCGGCCTTCGGCCTTGTCCTCACGCGTCGGACGGGCTGGGTGGTGTGGCTCGGGGGTGGGTGGGTTGAGCGGGGTGGGCGGGGCATCGCCCTTCGGCCTTGTCCTCA

>NZ_CP041607|15|14|7760680-7760792|CRISPRCasFinder
GGGGCATCGGCCTTCGGCCTTGTCCTCA	CGCGTCGGACGGGCTGGGTGGTGTGGCTCGGGGGTGGGTGGGTTGAGCGGGGTGGGC
GGGGCATCGCCCTTCGGCCTTGTCCTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143603011.1\|7763541_7764738_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP041607.1\|WP_097286346.1\|7744911_7746120_-\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|369642
NZ_CP041607.1\|WP_143603014.1\|7767626_7768934_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379258
NZ_CP041607.1\|WP_143603006.1\|7747267_7748209_+\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240643
NZ_CP041607.1\|WP_054234580.1\|7744647_7744884_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603010.1\|7762949_7763537_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP041607.1\|WP_097286349.1\|7748406_7751640_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_CP041607.1\|WP_054234575.1\|7753750_7754281_+\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NZ_CP041607.1\|WP_054234574.1\|7754396_7755395_+\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235491
NZ_CP041607.1\|WP_143603013.1\|7766284_7767529_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225755
NZ_CP041607.1\|WP_143603007.1\|7751866_7753723_+\|acetolactate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236098
NZ_CP041607.1\|WP_054234564.1\|7772106_7772313_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603009.1\|7761286_7762852_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|184957
NZ_CP041607.1\|WP_143603016.1\|7772469_7774404_-\|glycoside-hydrolase-family-97-protein	unknown	unknown	gnl\|CDD\|371140
NZ_CP041607.1\|WP_143603008.1\|7757497_7760464_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NZ_CP041607.1\|WP_054234565.1\|7770091_7771732_+\|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143441
NZ_CP041607.1\|WP_143603005.1\|7746183_7747191_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NZ_CP041607.1\|WP_054234573.1\|7755825_7757415_+\|phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|237436
NZ_CP041607.1\|WP_143603015.1\|7769115_7770042_+\|proline-dehydrogenase	unknown	unknown	gnl\|CDD\|223580
NZ_CP041607.1\|WP_143603012.1\|7764785_7766237_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224089

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143603011.1\|7763541_7764738_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19671e-52
NZ_CP041607.1\|WP_097286346.1\|7744911_7746120_-\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	8.19712e-88
NZ_CP041607.1\|WP_143603014.1\|7767626_7768934_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	1.1908e-20
NZ_CP041607.1\|WP_143603006.1\|7747267_7748209_+\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240643	cd12166, 2-Hacid_dh_7, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.49563e-146
NZ_CP041607.1\|WP_143603010.1\|7762949_7763537_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.17924e-11
NZ_CP041607.1\|WP_097286349.1\|7748406_7751640_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.52281e-74
NZ_CP041607.1\|WP_054234575.1\|7753750_7754281_+\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	8.34941e-89
NZ_CP041607.1\|WP_054234574.1\|7754396_7755395_+\|ketol-acid-reductoisomerase	gnl\|CDD\|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NZ_CP041607.1\|WP_143603013.1\|7766284_7767529_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|225755	COG3214, COG3214, Uncharacterized protein conserved in bacteria [Function unknown].	3.03143e-64
NZ_CP041607.1\|WP_143603007.1\|7751866_7753723_+\|acetolactate-synthase-large-subunit	gnl\|CDD\|236098	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated.	0
NZ_CP041607.1\|WP_143603016.1\|7772469_7774404_-\|glycoside-hydrolase-family-97-protein	gnl\|CDD\|371140	pfam10566, Glyco_hydro_97, Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.	3.83e-79
NZ_CP041607.1\|WP_143603009.1\|7761286_7762852_-\|MFS-transporter	gnl\|CDD\|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	3.08926e-75
NZ_CP041607.1\|WP_143603008.1\|7757497_7760464_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	7.08287e-37
NZ_CP041607.1\|WP_054234565.1\|7770091_7771732_+\|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|143441	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), families 4 and 17: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), also known as ALDH4A1 in humans, is a mitochondrial homodimer involved in proline degradation and catalyzes the NAD + -dependent conversion of P5C to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Also included in this CD is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences.	0
NZ_CP041607.1\|WP_143603005.1\|7746183_7747191_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	3.55085e-128
NZ_CP041607.1\|WP_054234573.1\|7755825_7757415_+\|phosphoglycerate-dehydrogenase	gnl\|CDD\|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_CP041607.1\|WP_143603015.1\|7769115_7770042_+\|proline-dehydrogenase	gnl\|CDD\|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	7.6557e-47
NZ_CP041607.1\|WP_143603012.1\|7764785_7766237_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	2.6529e-117

>NZ_CP041607.1|WP_143603008.1|7757497_7760464_-|AAA-family-ATPase
MAQTSGTPFIGRDDELARLTGVLDRARAGTPRAVVLSGDAGVGKTRVLTEAAAHATRTGMTVLTGHCVDLGDVGLPYLPFTEILGVLGADERFADALAAHPAVERLLGSGSGTDTDTGSRLRLFEGVAGLLADAADITPLLLVLEDLHWADQSSRDLLRFLLSRGVLQNPTPGSPTHHLALFASYRSDDLHRRHPLRPLLAELARLPSVDRLELRPMADAEVARLVRALRTDALSDTTVRRIVDRAEGNAFYAEELLAALPGDLDPAAPAMPSGLADLLLIRIEQLSDTAQQVLRTAAVAGRRVEHDLLRDAVQLPEEELESALREAVGRQLLVPGDDATYSFRHALAREAVYADLLPGERVRLHGAFAKLLAGRGHTAESAAERAHHSRESHDLADALTASLEAADHAHRVGAPAEELHHVEAALELWPAVDPGARPRKGDPVTLTLRASAAAAHAGETHRAVSLTRAALARAGSDADSELAARVRYTLAGNLMRVDSLKAAFTYSSEALAMIPAEPPSHTWVWAAATHVMAARYMGHDEDAERVARQALRTAEELRLADAQADLIISLVGLEDHNRRTAEGRERLRQARDLARRAGNVSVEMRALFNLAIGAYESGALDECLTWLAEGLERANRSGLVSSPYALELRYLQSLILYTLGRWDECARAATVDAERLPPAGGFAVGPALYVALARGEEGAAERARALLDGPFDWMATLVAGIVLTDAAALRGDPEGAVASVRATLASLSDGSGNGRPDIGVRLAALALSAVADAAVELRLTGDGAGARRWADLATELVEVARSTAAKGEDGSRQGPEGLAWLARAEAEWLRAHSGPEVAAWEQAVAAFDYGDPYELARCERRLAEALLVADRREEAAERARAARDTAVRLGAVPLREELDTLIRRGRLADSPSAADRVPALTARESDVLRLLARGRTNRQIGEELFITGKTASVHVSNILAKLGASGRTEAVAIAYREGLVEPPRDSRA
>NZ_CP041607.1|WP_054234573.1|7755825_7757415_+|phosphoglycerate-dehydrogenase
MSSKPVVLIAEELSPATVDALGPDFEIRHCNGADRAELLPAIADVDAILIRSATKVDAEAVAAAKKLKVVARAGVGLDNVDVSAATKAGVMVVNAPTSNIVTAAELACGLLLATARHIPQANSALKNGEWKRSKYTGVELAEKTLGVVGLGRIGALVAQRMSAFGMKVVAYDPYVQPARAAQMGVKVLSLDELLEVSDFITVHLPKTPETVGLIGDEALHKVKPSVRIVNAARGGIVDEEALFSALKEGRVAGAGLDVYAKEPCTDSPLFELDQVVCTPHLGASTDEAQEKAGVSVARSVRLALAGELVPDAVNVQGGVIAEDVKPGLPLAEKLGRIFTALAGEVAVRLDVEVYGEITQHDVKVLELSALKGVFEDVVDETVSYVNAPLFAQERGVEVRLTTSSESPDHRNVVTVRGTLGDGQEVSVSGTLAGPKHLQKIVAVGDYDVDLALAAHMVVLSYEDRPGVVGTVGRILGEAGINIAGMQVARAAAGGEALAVLTVDDTVPQNVLSEVAEEIGATSARSVNLV
>NZ_CP041607.1|WP_054234574.1|7754396_7755395_+|ketol-acid-reductoisomerase
MAELFYDDDADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQGLRVVTPSEAAAEADVIMILVPDPIQAQVYEESIKDNLKDGDALFFGHGLNIRFGFIKPPAGIDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDSTGSAFPLALSYAKGIGGTRAGVIKTTFTEETETDLFGEQAVLCGGTAALVKAGFETLTEAGYQPEIAYFECLHELKLIVDLMYEGGLEKMRWSVSETAEWGDYVTGPRIITDATKAEMKKVLAEIQDGTFAKNWMEEYHSGLKKYNEYKTQDENSLLETTGKELRKLMSWVNDEA
>NZ_CP041607.1|WP_054234575.1|7753750_7754281_+|acetolactate-synthase-small-subunit
MSTKHTLSVLVENKPGVLARITALFSRRGFNIDSLAVGVTEHPDISRITIVVNVIEALPLEQVTKQLNKLVNVLKIVELEPGSAVQRELVLVKVRADNETRSQIVEIVQLFRAKTVDVSPEAVTIEATGGSDKLEAMLKMLEPFGIKELVQSGTIAIGRGARSITDRSLRALDRSA
>NZ_CP041607.1|WP_143603007.1|7751866_7753723_+|acetolactate-synthase-large-subunit
MPMTEQATGAHHPQPRPRSGGQQSAPEHVTGAQSLIRSLEEVGAETVFGIPGGAILPAYDPLMDSTRVRHVLVRHEQGAGHAATGYAQATGKVGVCMATSGPGATNLVTPIADAHMDSVPLVAITGQVASKAIGTDAFQEADIVGITMPITKHNFLVTKAEDIPRTIAEAFHIASTGRPGPVLVDIAKDALQAQTTFQWPPTQDLPGYRPVTKPHAKQIREAAKLITQAKRPVLYVGGGVLKAKATAELKVLAELTGAPVTTTLMALGAFPDSHPLHVGMPGMHGVVTAVTALQKADLIVALGARFDDRVTGKLDSFAPYAKIVHADIDPAEIGKNRAADVPIVGDAREVIADLVQAVQKEHSEGHAGDYAAWWKDLNRWRETYPLGYEQPDNGSLSPQQVIERIGQLAPEGTIFAAGVGQHQMWAAHYVQYEQPATWLNSGGAGTMGYAVPAAMGAKAGQPDRTVWAIDGDGCFQMTNQELTTCALNNIPIKVAIINNGALGMVRQWQTLFYNQRYSNTVLHSGPDADGKQPSAGTRVPDFVKLSEAMGCHAIRCESPEDLDKVIAEANSINDRPVVVDFIVHEDAMVWPMVAAGTSNDEIMAARDVRPDFGDNEDD
>NZ_CP041607.1|WP_097286349.1|7748406_7751640_+|EAL-domain-containing-protein
MDQRSDAAGPPTTLARGHAQTRPQRPWWSRWPSPPRAQRPQKACAPSAHGPAGPRADRVDPVSSPGALLSRRQLYGAGTGLIPQLVLALVCAGYAFGSALGWGSAGLALFMGDFGLSAAAGTAAVSCFLYARSRRSRFRPAWLLFALSSTMASLGNGVWGWYEVVLDRQVPSPSYADLFFLCFAPPAIVGLLVLAKRPVTKAGWVCLALDSWLIGGSLLTLSWSLALAQAAKFDGPSVAHTALSLAYPLLDIALVSMVLALHFRRSSVNRSAVNTAIGALALTVMCDALFTSPLLHNNYHSGQLLDAGWFAGSLLLAYAPWVGPRPGQPVADGHGTEEPRRDGHARVVHEHIPGPRQGGPGITQGSQGSQGSPQGSQGSQGHQEPQGAQEPQDGGHNRYPTTRPIAGSLAALTPYLAAAVCTLGILYNVLNGRSVDRVVLITAGLVVLALVVRQGIMLLDNITLTQELAQQENHFRSLVQGSSDVIMIAAPNGILRYVSPAAAGVYGRNAEELVGSELASLIHPEDLGCVVHEVRRFLAASHLEEPTTRIECRFKSGDGGWLNVESTVNRHHGGLIFNSRDVTERVRLQAQLQHNAEHDPLTDLPNRALFTRRVQQALSGRRSTDRGAALRGTAVLFIDLDGFKAVNDTIGHQAGDELLVQAARRLQDSVRQGDTAARLGGDEFAALIVGDGSGDRGAREQQILELADRLRIKLSQPYAIGGNDVRVAASIGVGFAEPGLGAGELLRNADLAMYRAKAAGKGRVELYAPQMQQDVVRKAELATRLRSALQDGEFALLHQPVVCLGNGRIVTVTAQARWRSSQGVLFTPAEFLRVAEDSDKTAELGRWMLEEAVEQAVERAAAGVTVPVAVRMSARRLLDRSMPLGSVEALLTRHGLASGSLIVELADTDPRVSLDELERRLNALRRLGVRIALDGFGSGYAAITTLRRLPVDVLKLDRGLVEGVVESARLHKITSGLLRIATDLGLQSVADGVDLPEQVVALRAMGCTHGQGMAFSGPLDEYRLRRALSCGHYPVPHGPAEPAFAGGGAGVYTSGVPAVFGGGTALRSHNETPVPPT
>NZ_CP041607.1|WP_143603006.1|7747267_7748209_+|2-hydroxyacid-dehydrogenase
MTSDVWLPFHADEIEGLPEGLSYRFWDGDQEFPADPAHCEFYVVPYMKAPGVGQRPLAEMTSLRVVQTLSAGVDHVLQGVQSLPAGVQLCNARGVHEASTAELALTLILASLRGVPGFVRAQDKGEWHAGFHPALADKSVLIVGYGSIGSAIEDRLTPFEVARVARVARSERTTARGPVHPLTELPALLPEADIVVLSTPLTDSTRGLVNAEFLAGMKDGALLVNVARGPVVDTKALLAELDSGRLTAALDVTDPEPLPQGHPLWQTPGALISPHVGGPTSAFLPRAKRLLTAQLNRFVNREPLGNVVLTTGA
>NZ_CP041607.1|WP_143603005.1|7746183_7747191_-|aldo/keto-reductase
MERRTIGAATLDVGAIGLGCMPMSWAYTCSRQRGEESLRAVHAALDRGSTLLDTADMYGPFTNELLVGRVLKERRSEAFVSTKVGLLVGEQHIVANGRPGYVRRACDASLRRLQTDVIDLYQLHRADPEVPVEETWGAMADLVSAGKVRSLGLCAVGARSARRAGARLHDGTIRQLERVQQVFPVSAVEAELSVWSTEALDALLPWCAARGVGFLAAMPLGNGFLTGTLTPGEGFEPDDLRARHPRFTAEMMAANQPIVVGLRRVARRHGLLGNTVTPAQVALAWVLAQGRHVVPVPGAKRERWVTENAGAAELRLTAEDLAEVAALPGARGSWD
>NZ_CP041607.1|WP_097286346.1|7744911_7746120_-|PQQ-dependent-sugar-dehydrogenase
MNSRTAASKGPLIVQRRVMKAVLAAAALVVTAGCSSGGGGGAPIGGLSPSSSGGTGTGASSAPRATETAAPAKGSVKVLRTVTENLKSPWGLAPLPEGGLLVSSRDEGTITRVDEKTGKKTELGQVPGVAPAGEGGLLGIALSPAYASDHMIYAYFTTASDNRIVRMLYDEKKPSGEQLGAPDTIFKGIPKGMIHNGGRIAFGPDRMLYAGAGETGDRGQAQDTKALGGKILRMTPDGDPAPGNPFDNSVVYSYGHRNVQGLAWDDKQRLWASEFGQDTWDELNQIKPGDNYGWPVVEGRSDDPKYHNPVAQWHTDQASPSGIAYAEGSIWMAGLRGQRLWRIPLKGTEAAAAPQAFLKGEYGRLRTVVPAGGDKLWLVTSETDGRGSPGKGDDRILELEVK
>NZ_CP041607.1|WP_054234580.1|7744647_7744884_+|hypothetical-protein
MFNMFEELFAPGRKHTNDERKRLELSRVDLNDGDPGRGPIDLTSGKVVVRLPKQERDQEREGGQGDTGEEPVSEPDES
>NZ_CP041607.1|WP_143603009.1|7761286_7762852_-|MFS-transporter
MTNSKHSTSTTPAPGGGLAGRREWTALGVLMLPLLLVSMDVSVLYFAIPAISADLEPSGTQQLWIFDIYAFVLAGLLMTMGSLGDRIGRRKLLLVGAAAFGTASVMAAYADSAEMLIAARAVLGIGGATLMPSTMAIIRTMFTDPGQRAKAIGLWSGVMTGGIALGSVMSGVLVEYFWWGSVFLVNLPAMVLLLVLGPILLPESKNPEPGRFDLLSVPLSMAAVLPVIYGVKEIPSEGWKFEYGASIVVGLIFAALFVQRQRTAKSPLISPELFRGRGFAAAVVLNLVSAFGMLGSAYFTTQYLQSVLGKSSMEAALWSLLPTVLVGVAAPVAAQLVQKGVHRAHVVSGGFVLGACGYGLLAFTRTDSMWLVLAGAGVLASGIVTVMSQMMDLALGTVPVGNAGAASSLLETGAEFGGALGMAVLGSIGTAVYRHEIPSGAPAPAQETLGGALAVAHGLPGGAGDALVRAAREAFTSGMQAAAIAGAVLLLGAAGVASATLRRVRVREIGAEAPHPEQAPA
>NZ_CP041607.1|WP_143603010.1|7762949_7763537_+|TetR-family-transcriptional-regulator
MGHREDLLEGAKRCLLEKGFVRTTARDIVKESGTNLASIGYHYGSKDALLTQAFVELVQEWGEKFAPHPEHEGAPGGSVERFHSVWTRMLESFEEFRPVWAASMEIVTQGERVPELRKLMATAQIEGRSGLVAMLTGLDEETLDERTVQSLGGFYQALLNGLMVQWLFDPASASTADDLTEGLRRVIEGATGPRD
>NZ_CP041607.1|WP_143603011.1|7763541_7764738_-|MFS-transporter
MTTTRPRVPAAASRPPLLTRPLLLRFVSMVGASASFFLLLSVVPRYATESGAGLATGALMLSTVLGELAAPRLVARYGYRVALIAGLTLLGAPALVLTVSDGMAWIVTVCLVRGLGFALTLVAGGALTASLIPAERRGEGLALVGVVSGVPSLIALPLGVWLAAHAGYGPVAVAAGVAALAAIVAVPGLPDREPTSGKPVGVLAGLRTGGLMRPGAVFATTALAAGIVVTFLPLAVPAAYGTVVAVALFVQPAASTAARWAAGRYGDRHGPARLLVPGLVLSAGGLSITAVTGSPVAVLVGVAVFGTGFGIAQNATLTLMYARVPATGYGTVTALWNIAYDGGMGVGAAGFGVLAGVTGYPSALAVTAALMLVALIPAYRDARADRGSGTSPTGVVAG
>NZ_CP041607.1|WP_143603012.1|7764785_7766237_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MPLQWAGLSPELLLSVDRESGEQLRAQLERQLRDAIRTGRLGAGERLPSSRELAREMGLSRGLVQDCYAQLQSEGYLVTRVGSATRVAACAHVPPAPAPHRSAPEPLIADFRHGVPDLTGFPLSDWLWALREAGRTLPTADLDYGDPRGSRVLREVVAGYLRRVRAAAADPERIVVCSGYAQGLGLALESLAGAGVRVVAYEDPGAPATVTAAAAAAGLTAVPVPVDEQGIDVRALEATGARAVVVTPAHQWPTGVVLAPERRLALIEWATRRDAYVVEDDYDAEFRYDREPVGALQGLAADRVVSIGTVSKSLAPALRIGWLLCPPALTAPITATKLRTDRGSPTLDQLALARLVESGRYDRHLRRMRATYAARRTALVTALGAHAPEVRLTGLAAGFHAVAHLPGTDADAERAVVDGARARSVGLYGMSACRSNRATAPPQLVLGFGDVGVRAITEGIATIGDLLAGARRPGRLVAGPDRS
>NZ_CP041607.1|WP_143603013.1|7766284_7767529_-|winged-helix-turn-helix-domain-containing-protein
MPTSQQKLTISQVEARRLALSRQWLGGVRPSGDGEGLRAVLRSLRYLQLDPISVVAPSHELVVWSRLGAGAGSHLGALWWEERWLFEYWAHAAALVLTEDYPIHRVSMDGYPPKNLSLTKVWMEANEGLLAHILTRLAEGTPLPTDAFEDRSVMEWPSSGWTAGRNVERMLTFLWLQGRIMVAGREAGRRLWGLPDACLPPGADRVAVSAREMVTTAAEHTLRALGVARPLDIKQYFLRGKYDGLAEVLRTLTREGRVLPVRVEGATSATETWYVHVDAMAELEAIRAGDWHGRTALLSPFDNLVGDRRLTERLWGFAFRNEMYVPKAKREYGYYLLPILHEDRLVGRISPRRDRNRGTLLVEGLYLEPDVRPTVALRKAVTGQLADLATLVGATDVEYGETVPEPWRAALRRS
>NZ_CP041607.1|WP_143603014.1|7767626_7768934_-|PucR-family-transcriptional-regulator
MSDEHRDHREHRDHREHRDHRGDHGGYQELVDEISALLGVPATLENRDFELIAFGAYDSEGELDPSALDPVRTRSILTRRSTAAVRTWFEGFGITRATAPVHIPPTPEAGVYRGRICLPVRHRGVVLGYVWLLEDDPGPSEAQLSAAMEVAARIGDLLADEAQAGADLTRELRAVLTAERGWQRDMAVAELRTALGPRGDGLHAVVCVAPWPSADPDDAPSVRTVPGATALCTVPWGATGQSLALLVRLRSADVLTPALTAATRFVREADGDRGGGQGTEAPRPSSTPGTSGTTKGAGTTVAAGVAGARVGLAELGAAWQEASAAARAVLAEPRLGPVAEWASIGPFRLLTALPPEAAHDPAVRTLLSPAHRELARTAEVFLDCAGQAGRTAAELGIHRQTLYYRLSRVEQLTGLDLDDGEDRLLLHMALKGARL
>NZ_CP041607.1|WP_143603015.1|7769115_7770042_+|proline-dehydrogenase
MLGPVILAASRSDRMRRFVSAAPGTKQVVARFIAGESVDQVVPVVQDAVAKGLEVTLDVVGEDITTREQAFAARDAYLELIEHLKELDLGTKAEMSIKLSMFGQALEGGHELALANVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRKDFPRTGCVIQAYLYRTEADARRLAASGSRVRLVKGAYKEPAEVAYQDKAETDKAYVRVLRVLMEGEGYPMIGSHDPRLISIAQELARKAGRKLDEYEFQMLYGIRSEEHLRLAAEGHRMRVYTAFGTDWYGYFMRRLAEKPANLLFFARSILTKG
>NZ_CP041607.1|WP_054234565.1|7770091_7771732_+|L-glutamate-gamma-semialdehyde-dehydrogenase
MDAVTQVPTPVNEPVHGYAPGSPERARLEAKLKELAENPIELPMTIGGEKRLGGGERFEVVQPHNHKAVIGTGAHATQQDAQDAIDAALAAAPAWRAMSFDDRAAIILRAAELLAGPWRETLAASTMLGQSKTAQQAEIDCPCELVDFWRFNVAYARQILAEQPPANSPGVWNRLDHRPLEGFVYAITPFNFSAIAGNLPTAPALMGNVVVWKPSPTQTHAAVLLMRLLEEAGLPKGVINLVTGDGIEVSKVALEHRDLAGIHFTGSTKTFQYLWKTVGNNIEKYRSYPRLVGETGGKDFLVAHPSADRAVLKTALTRGAFEYQGQKCSATSRAYIPASIWNSGFKEEFAAEVDYLTMGDVTDLANFVGAVIDERAFAKNKAAIDRAKTDPACTIVAGGSYDDSVGYFVRPTVVECSDPENEVFKTEYFGPFLAVHVYEDETDEGYDEMLTQMESASDYALTGSVVSGDRAAAAYTMEKLRYAAGNFYINDKSTGAVVGQQPFGGGRSSGTNDKAGAPQNLMRWTLTRAIKETLVPPTDYTYPHMG
>NZ_CP041607.1|WP_054234564.1|7772106_7772313_-|hypothetical-protein
MSDTTKALLEGGPDDLPERIVPVPPPGTDVKIELRGGYEHFRATPRQADTPEGRLPVYEWWERTEFAG
>NZ_CP041607.1|WP_143603016.1|7772469_7774404_-|glycoside-hydrolase-family-97-protein
MSVQLRARTIVLTLCSTLLATAVAALPARAEGTARAAWEVKGPHGSPTAVVALDRSDGRPTLAVRREGRTVLEPSPLGLVTEQTDFSRGLTLTGRSERTITEHYTSPTGKSRDRVARMTEARFRFRAADGARLDLVTRVARDGVAYRYVLPQNHGNVLREASAFTLPTDANALLGGYRADNELRFTRYDSAAAAPAGAYMMQGLFRTDGGNGAAADGDYALIAESDVNGTYAGAHLTHTADSSTYGLSLWNDEPILTTGPLTTPWRAIVTGDLATVTESTFTDDLAPASRVHDTSWIKPGPALWTWLAGGKEAGQSLAAQEKYVDYAAERGWRYEVVDAGWYFKTGEWEVIDPRWQTDSWMPELVRYAAAKGVGIHVWLHYSLLTDPVEREKWLSTLAGWGVKGVKIDFMDSESQERMRWYDDVLESTARHHLMVNFHGSTIPKGIQRTWPQVMSMEGVGGEEKRNNTAEQLASLPFTRNVIGSMDFTPGAFHRPYRPNVASDAGELGLSVLYESGIQNLSGTPESYDARPEARRYLEQLPARWEETRLLTGDPGRSAVLARRAADGRWFLGGTFTGAARTVDVPLRLGAGRWLVETLTDGPSGLLRETHVVRGGGTLTVPVVADGGFAALACRAREGRTTCEN

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Crispr_ID: NZ_CP041607_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_16

7960372-7960516

Orphan

Consensus_repeat	Method
GTCTGTCGCTGGTCGCGCAGTTCCCCGCGCCCCTCGGGCCGGGGCTGCGCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_16

>merge|NZ_CP041607|16|7960372-7960516|CRISPRCasFinder
GTCTGTCGCTGGTCGCGCAGTTCCCCGCGCCCCTCGGGCCGGGGCTGCGCCCCGAGTGCCTCACCGGCCCGGATTCGTTCGGCTGCGGGGTGTCTGTGGCTGGTCGCGCAGTTCCCCGCGCCCCTCGGGCCGGGGCTGCGCCCCG

>NZ_CP041607|16|15|7960372-7960516|CRISPRCasFinder
GTCTGTCGCTGGTCGCGCAGTTCCCCGCGCCCCTCGGGCCGGGGCTGCGCCCCG	AGTGCCTCACCGGCCCGGATTCGTTCGGCTGCGGGGT
GTCTGTGGCTGGTCGCGCAGTTCCCCGCGCCCCTCGGGCCGGGGCTGCGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_054235322.1\|7947510_7948434_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NZ_CP041607.1\|WP_143603074.1\|7974915_7975629_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235746
NZ_CP041607.1\|WP_143603066.1\|7951492_7953325_+\|chitinase	unknown	unknown	gnl\|CDD\|119350
NZ_CP041607.1\|WP_143603075.1\|7975646_7976138_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054235310.1\|7968399_7969335_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP041607.1\|WP_097286428.1\|7949307_7950726_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274522
NZ_CP041607.1\|WP_054235323.1\|7946350_7947511_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP041607.1\|WP_143603069.1\|7958610_7960272_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NZ_CP041607.1\|WP_143603065.1\|7950901_7951378_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603067.1\|7953312_7954170_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_CP041607.1\|WP_060901190.1\|7954340_7955675_-\|4-aminobutyrate--2-oxoglutarate-transaminase	unknown	unknown	gnl\|CDD\|235685
NZ_CP041607.1\|WP_054235312.1\|7965643_7967341_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270298
NZ_CP041607.1\|WP_143603073.1\|7972606_7974880_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379625
NZ_CP041607.1\|WP_143603072.1\|7970630_7972610_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|367090
NZ_CP041607.1\|WP_143603071.1\|7967368_7968403_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226666
NZ_CP041607.1\|WP_143603076.1\|7976254_7978306_-\|glycoside-hydrolase-family-31-protein	unknown	unknown	gnl\|CDD\|224418
NZ_CP041607.1\|WP_060901188.1\|7960844_7962290_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143465
NZ_CP041607.1\|WP_143603068.1\|7956007_7958461_+\|ATP/GTP-binding-protein	unknown	unknown	gnl\|CDD\|237871
NZ_CP041607.1\|WP_143603070.1\|7962412_7965268_-\|sugar-hydrolase	unknown	unknown	gnl\|CDD\|178629
NZ_CP041607.1\|WP_054235321.1\|7948434_7949235_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224098

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_054235322.1\|7947510_7948434_+\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	2.69905e-79
NZ_CP041607.1\|WP_143603074.1\|7974915_7975629_+\|hypothetical-protein	gnl\|CDD\|235746	PRK06215, PRK06215, hypothetical protein; Provisional.	5.85582e-128
NZ_CP041607.1\|WP_143603066.1\|7951492_7953325_+\|chitinase	gnl\|CDD\|119350	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus.	1.66369e-146
NZ_CP041607.1\|WP_054235310.1\|7968399_7969335_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.24251e-60
NZ_CP041607.1\|WP_097286428.1\|7949307_7950726_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	3.37275e-65
NZ_CP041607.1\|WP_054235323.1\|7946350_7947511_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.51226e-154
NZ_CP041607.1\|WP_143603069.1\|7958610_7960272_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	2.30505e-32
NZ_CP041607.1\|WP_143603067.1\|7953312_7954170_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	2.8305e-29
NZ_CP041607.1\|WP_060901190.1\|7954340_7955675_-\|4-aminobutyrate--2-oxoglutarate-transaminase	gnl\|CDD\|235685	PRK06058, PRK06058, 4-aminobutyrate--2-oxoglutarate transaminase.	0
NZ_CP041607.1\|WP_054235312.1\|7965643_7967341_+\|extracellular-solute-binding-protein	gnl\|CDD\|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	9.41657e-49
NZ_CP041607.1\|WP_143603073.1\|7972606_7974880_+\|hypothetical-protein	gnl\|CDD\|379625	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain. This domain represents a domain found to the N-terminus of the glycosyl hydrolase 65 family catalytic domain.	4.63419e-29
NZ_CP041607.1\|WP_143603072.1\|7970630_7972610_+\|beta-galactosidase	gnl\|CDD\|367090	pfam02449, Glyco_hydro_42, Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.	0
NZ_CP041607.1\|WP_143603071.1\|7967368_7968403_+\|ABC-transporter-permease-subunit	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	4.68996e-102
NZ_CP041607.1\|WP_143603076.1\|7976254_7978306_-\|glycoside-hydrolase-family-31-protein	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	9.59459e-172
NZ_CP041607.1\|WP_060901188.1\|7960844_7962290_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143465	cd07147, ALDH_F21_RNP123, Aldehyde dehydrogenase family 21A1-like. Aldehyde dehydrogenase ALDH21A1 (gene name RNP123) was first described in the moss Tortula ruralis and is believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and ALDH21A1 expression represents a unique stress tolerance mechanism. So far, of plants, only the bryophyte sequence has been observed, but similar protein sequences from bacteria and archaea are also present in this CD.	0
NZ_CP041607.1\|WP_143603068.1\|7956007_7958461_+\|ATP/GTP-binding-protein	gnl\|CDD\|237871	PRK14965, PRK14965, DNA polymerase III subunits gamma and tau; Provisional.	0.00100575
NZ_CP041607.1\|WP_143603070.1\|7962412_7965268_-\|sugar-hydrolase	gnl\|CDD\|178629	PLN03080, PLN03080, Probable beta-xylosidase; Provisional.	4.66837e-56
NZ_CP041607.1\|WP_054235321.1\|7948434_7949235_+\|ABC-transporter-permease	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	2.03434e-65

>NZ_CP041607.1|WP_143603069.1|7958610_7960272_+|PucR-family-transcriptional-regulator
MRPTLASIVHHSALKLTVRAGEDRLDVPVRWAHVSELADPVPYMEGGELLLITALQLDAEDPDVMRRYVKRLVGAGVVGLGFAVGVNYDEIPKALVDAAEEEGLPLLEVPRRTPFLAISKAVSAAIAADQYRAVTAGFAAQRELTKQALNDGPEGLLSALAGQVDGWAALYDASGAVVATAPEWAGRRAARIIPDVERLRERPAPASSVVGGEDRVELHSLGTGRRPRAALAVGTAAALGTAERYAVHSAIALLTLTTERSRSLHAAEQRIGAAVLRMLLAGQPEHARTVAGDLYGELLDAPFRLILAESASASAARAHADGHARVAAAKPSKAPVVVPDPTNGDPLGGLAEIVESAAARSGESVLVVPDGERLVVLAVDGGAAVTACGEYAAALEAARIATREQPVGEEDELVVGLSAPAGPIAAAAAYKQAEQALSVARRRGRSLVEHEELAAGSVLPLLADDAVRAFADGLLRPLNEHDATGRGDLVASLRAWLSRHGQWDAAAADLGVHRHTLRYRMRRVEEILGRSLDDPDVRMELWLALKATAAAGE
>NZ_CP041607.1|WP_143603068.1|7956007_7958461_+|ATP/GTP-binding-protein
MDSDGTQDARGGHTGAVPGPAVPPPPGRAPASPPPGVPPVLRGTPPRPAGLPSVPEQSPAPRPTVADWLDRPRPAAGPGIWRYGYRVRRPSKGRERLSPVTIVGLAVPLVVALVVWSLWRHGSVPYMWVVLKVFTPDGWWWSGTTSPKVWQGVEAIEVYNGVFFGVLVYTMGRLGSWPEVVRHYVTARPQPLRAALAGLGALIALTFVFPDAFPGVGWDALPVVAPLFSLVALVSGGYDLFQSQLITDGLYTLITLLVLWPFARIGAWRRYAREWLAARAARNEAQEAGTAKFAPDLPAAQWPELRDAGQHEAADLLTAEVLGGRMNDVDCARVRRAWTTAKWDATRLAAFADTVLRRGGAAWTHPSGARDLPARTAAHDVLVGQVRIGRWTTGDRTPEAYDGGGAALDPEALGTSLLAVGPSGSGKTRHLVGPVVESLALQALTGRCAVVAVAAAGTPLGPDSAFDVVVKIGDPASVHDLDLYADSDDPDEAASFLAEGLAGDLDAVAGQRATTALAQLLGPYRAVHGTFPPMSVLRELLEGVPEALTALHEALFGPQHAGMRRELEARMRQVGSPADAGPALADRLALLDRPAFADFFGAGGTTRAFSLRAVAHHPLRVRIDLPEHGHEEAARLLARLVLAQFTAVVRGGERPHFVCLVLDDATGTLTPDSVRRIQRLRSQNAGVVLALRTIGDIPEALHGPLYGAVGCRMAFSGVTTWDGSRFAHAWGTEWVETRDVAKHTVFADQPMTRAIHALRKLVTGKAVTTDAVTIRKVERERWSASELAHEVPPGHAVLSLTTVGGEHAPPLLVDLRS
>NZ_CP041607.1|WP_060901190.1|7954340_7955675_-|4-aminobutyrate--2-oxoglutarate-transaminase
MTALPQERRVVTAIPGPKSQELQARRIAAVAAGVGSVLPVFTTRAGGGIIEDVDGNRLIDFGSGIAVTSVGASAEAVVRRASAQLQDFTHTCFMVTPYEGYVAVAEALAELTPGDHAKKSALFNSGAEAVENAVKIARAYTKRQAVVVFDHGYHGRTNLTMALTAKNMPYKHGFGPFAPEVYRVPVAYGYRWLTGPENAGAEASAQAIDMINKQIGADNVAAIIIEPVLGEGGFIEPAKGFLPAISKFAKDNGIVFVADEIQSGFCRTGQWFACEDEGIVPDLITTAKGIAGGLPLAAVTGRAEIMDAAHAGGLGGTYGGNPVACAGALGAIETMKELDLNAKAKNIEAVMKARLGAMAEKFDVIGDVRGRGAMIAIELVKDRATKEPNPEATAALAKACHQEGLLVLTCGTYGNVLRFLPPLVIGEDLLNEGLDIIEQAFARI
>NZ_CP041607.1|WP_143603067.1|7953312_7954170_-|phosphatase-PAP2-family-protein
MRDTPRPQGTVGDTGSRPPQLRPGRALAHTPGASGSGSPHRSDSRSPQTPRGARRPDLDGRLGTTPPVPGRPTFLRGRLGLFGPLGFLGLPALLFALITWQVAAHGPLARADEHLSDRLVHPDRVSGLLADLGDVTVAVPVLAVVLGYVAWRARAAGRERWWLPSLATAALMAVVPALIVPLKELVARPGPPVMGPGTGFYPSGHTATAVIAYGGAALVLIPWLRGAGARRALLVGCLALNLGVAFGLVRRGYHWPLDVAASWCLCAVLLLSLRLLLGRNGRQPK
>NZ_CP041607.1|WP_143603066.1|7951492_7953325_+|chitinase
MPPCPEAVVDRTERTRPSTRQRLLAVCTATVLAVPGLAALSSAARAADADLVRNGGFEAGLDGWTCTAGAVVNSPVRSGSSALRATPAGSDNAQCSQTVTVKPDSQYTLAGYVRGSYVYLGASGTGTTDVSTWTQSAPDWQQLTTTFRTGPSTTKVTLYTHGWYGTGAYYADDVSLVGPGADPGQPPAAPTGLATGTVTSSTVALSWSPVTGATGYAVYRDGVKVQTATGTSTTVSGLAPSTAYAFQVAAVNDAGESAKSATVTATTSTGSGGSTGHALVGYLHASFANGSGYTRMSDVPDSWDIIDLAFGEPTSTTSGDIRFTRCPVTECPTVESDADFKAAIKAKQAAGKKVLISIGGQNGQVQLTTTAARDTFVSSVSKIIDTYGLDGLDIDFEGHSLSLDAADTNFKSPTTPVIVNLISALKTLKAKYGSTFVLTMAPETFFVQLGYQYYGTGKWGGQDPRAGAYLPVIYALRNDLTLLHVQDYNSGSIMGLDNQYHSMGGADFHIAMTDMLLTGFPVAGDANNVFPPLRPDQVAIGMPASTNAGNGYVAPSEVTKTLDCLTRKTNCGSYTTHGSWPGLRGLMTWSINWDRYGSWEFQRTFDGYFG
>NZ_CP041607.1|WP_143603065.1|7950901_7951378_+|hypothetical-protein
MTGAKTAVEWLASVAPDPEACRREWETNPQRVALLPAGRLWDVLILPGELGYPTLDVLTRVIDRLGPVLVDFGDARMGFFVPPGTAARWLGTGVRTAGRGTWIVVPYPGRTHGGVRWLVPPDGTGTLTDPALLELAMHEATAGIAGNEGRQPPRGGLR
>NZ_CP041607.1|WP_097286428.1|7949307_7950726_+|FAD-dependent-oxidoreductase
MAPSAMTRWTTSLSEAQPVPYWLDDPGKPHPEPALTGAETCDLLVVGGGYSGLWTALIAKERDPQREVVLLEGREVGWAASGRNGGFCAASLTHGLANGLTRWPDEIRKLEELGARNLDEIEAAVARYSLDCDFERSGEIDVATEPHQAAELREWHEELRERGLADGIEFLDADAVREQVDSPTFLAGLHDRRGVAMLHPAKLAWGLKRACLRLGVRVYEHTPALALKAYGAGMAVRTPYGSVRARKVALATNIFPNLVKRVRAYTVPVYDYALMTEPLTADQLASVGWKNRQGLGDSANQFHYFRLSADNRILWGGYDAIYPYGGRVRAEYDDRPETYAKLAGHFFTCFPQLEGVRFTHAWGGAIDTCSRFSAFFGTAHHGKVAYAAGYTGLGVGATRFGADVMLDLLAGERTERTELEMVRKKPLPFPPEPFAWTGIALTKWSLARADAHGGRRNLWLRTMDKLGLGFDS
>NZ_CP041607.1|WP_054235321.1|7948434_7949235_+|ABC-transporter-permease
MAFVRWFKRNLVVIGGLLTLGYLLLPNVIVTVFSFNKPKGRFNYEWQQFSLDAWRDPCGVADMCGSLSISLQIAVWATIGATILGTMIAFALVRYRFRARGAVNSLIFLPMAMPEVVMAASLLTLFLNLGAQLGFWTILIAHIMFCLSFVVTAVKARVMSMDPRLEQAAQDLYAGPVQTFLRVTLPIAAPGIAAGALLAFALSFDDFIITNFNAGSTVTFPMFVWGSAQRGTPVQINVIGTAMFIVAVLFVLAGMVVSNRRSKQKA
>NZ_CP041607.1|WP_054235322.1|7947510_7948434_+|ABC-transporter-permease
MASVTEAPLLAPQPDKKPPRKRGRLVPYWLLLPGILWLLIFFALPMVYQASTSVQTGSLEQGFKVTWHFQTYWNALADYWPQFLRSVLYAGAATILCLVLGYPLAYLIAFRAGRWRNVVLILVIAPFFTSFLIRTLAWKTILADGGPVVGALNTLHVLDVTNWLGFTSGDRVLATPLAVVCGLTYNFLPFMILPLYTSLERIDGRLHEAAGDLYAKPFTTFRKVTFPLSMPGVVSGTLLTFIPASGDYVNADLLGSTDTRMVGNVIQTQFLRILDYPTAAALSFILMAAILIMVTLYIRKSGTEDLV
>NZ_CP041607.1|WP_054235323.1|7946350_7947511_+|ABC-transporter-ATP-binding-protein
MTTDNGGDVRLSGISKTYGSFTAVHPLDLTVPEGSFFALLGASGCGKTTTLRMIAGLEEPSSGTVFLGDQEVTHLPPYKRPVNTVFQSYALFPHLDIFENVAFGLRRRGIKSVKKQVEDMLELVQLGEQARKKPHQLSGGQQQRVAVARALINHPKVLLLDEPLGALDLKLRRQMQLELKRIQTEVGITFVHVTHDQEEAMTMADTVAVMNAGRVEQLGAPADLYENPQTTFVANFLGTSNLIEAAVDSKDGDDIVLAAGGGKLVLPQARCSAPTTTGGKVLVGVRPEKISLTHVDDAGEIPAGRNRITGRIADSSFIGVSTQYVVDSAVCPEFEVYSQNIDRDARLTPGAEVVLHWSPAHTFGLDAAQDIDAGVETVEPEEGVAA
>NZ_CP041607.1|WP_060901188.1|7960844_7962290_+|aldehyde-dehydrogenase-family-protein
MTSTHAFWLAGRQATGETTFDVTSPWDGRVVGQVSVPTEAQVEEAVAAAYAVRDEFAATPAHVRAAALDHVSKRLVERTEEIAQLISAENGKPIKWARGEVGRAVSVFRFAAEEARRFNGGEAQRLDTDLGGQGRLALTRRFPKGVVLGIAPFNFPLNLCAHKIAPAIAAGAPIILKPAPATPLSGLIIGDLLAETELPAGSWSILPVSNDRMPALVQDERLPVISFTGSEKVGYAIMDSVPRKHCTLELGGNGAAVVLADWASDEDLDWAATRIATFSNYQGGQSCISVQRVIADASVYDRLLPRIVAAVEAQVTGDPSDDKTDVGPLVSEDAAQRVESWVDEAVRSGATLLTGGKRDGASYAPTVLTDVPAEATISCEEVFGPVLTVRKVDGEAEAFAAVNDSKYGLQAGVFTHDLQVAFRAHRALEVGGVVVGDVPSYRADQMPYGGVKQSGVGREGVKFAMDDYTYERVLVLTGLAL
>NZ_CP041607.1|WP_143603070.1|7962412_7965268_-|sugar-hydrolase
MTAQTPPTPPFRDPQLPFAKRIDDLLARLTLDERIAFLHQFAPAVERLGVAAFRTGQEALHGVAWMGPATVFPQAVGLGATWNDELVRRVGEAVSAEVRAMRARDDRVGLNVWSPTVNLLRHPLWGRNEEGYSEDPKLTSAIATAYTRGLRGDHPDYWRTAPVLKHWLAHNNETDRDTTSSSVRPRVLHEYDLRAFRATVEAGAVAGVMPAYNLVNGRPNHVSPYLGEHLRTWTDQDLLVCSDAGAPSNLVDSEHYFDTHEEATAAAILAGVDSFTDHGTDGSKIVDRVRGALEKGLLSEADIDTAVRRQLAIRFRLGEFDPHTDPHAGTSDFDTPAHRALAREAAEQAIVLLKNDGLLPLGPGVRVAVVGLLADECKLDWYSGTLIHRSTPLEGLYERFGAERVDFAEGVDHVRLRTSSGTYLSVPLAGDADDEVRGAEGALDPALLAGRTDLPPLTTDATGTDLALIDWGEGLLTLRAPDGRYLSVAEDGYLRASADQPGGWVVQETFRLEPAGSRSGSHGSGHLLRHVGTGGHLSVAADGVRVADDAPEIFELEFAERGEDAVARVAEAADVVVVVAGNDPHINGRETEDRTTLRLPAHQERLLRAARAANPDTVLALVSAYPYAVDPTDLPAVLWTAHGGQAAGTALARVLAGDVSPAGRLPQTWYASDADLPDLLDYDVIGGRQTYLYFEGSPLFPFGHGLAYTTFAYEDLEVTEARAALKVSFTVTNTGEAPADEVAQLYARAVDPSVPRPRRELLAHRRLHLTPDASERLTFELPLSALEFWDVAVGRTRLEPGAYELLAGASSEDIRLRTTITLTGEPATPRPVRETGLNAADFDEQRDTEIVDRTKVSGDAVSPRADATGELVHRGCDFGTGVTRVEVEASGEGVVEVSLDGGPSLATVAFDGTKSPYDYTTIGAEFAAHGVHDLRLRLRGPLRLARVGFSG
>NZ_CP041607.1|WP_054235312.1|7965643_7967341_+|extracellular-solute-binding-protein
MTPNTATSAPSAPSRRSFLASTAVAAAAVAGGMPLLAACGGSDSGSGGGTSAGKSAKKLLPAYVATNVVTPDIAAKNGSAVGFTSKLDIASLKTSVPKKLGKGGKVSIMSPFWGSPPKSDNAYYKAMNDLIGVDVEWQNQDGNTYDQKLGAVLASSDIPDVVVIPGWNMGGKIPSAIIGKFADLGPYLSGDAIKQYPNLAAIPTDAWQRSLFGGKLRGLPQPSPYVTGIVPLYRKDIFDKEGYQVPTSADEFMALCKEITNAKAKRWACLDMKWTAFQSFGVLSGSEKPLGWNLVDGKLVYRIETQEYLEALEWTRKLFAAGYVHPDAKLGKSAATDPGPKFAAGEFLIYAQNISQWWSRTAEQATQNPDYKIWGMDIFGHDGGSPTLWAEQPAGIFAFVSKKASESVIRDVLAVANVTAAPYGTKEYMLTNYGVEGTHYTVKNGVPTKTDQGNNEVINAYVMVASPTATIAHPDFPEVAKAQVEWQQRMGAFTKKSSFYGMQITEPSRYTNLSNDFEQLEDDIVRGRKKISDMQQAVSDWKSKGGDQLRDWYKKLLDENGPAAS
>NZ_CP041607.1|WP_143603071.1|7967368_7968403_+|ABC-transporter-permease-subunit
MSHSTVPRSGTEADTREKTPVASGGATGSREKRPSGKVSLRLRFRRDRVLLLMTLPAVLLVLLFNYVPILGNIVAFQDYDPYISDNGIVSMLHSPWVGIENFQRVFEDSAFWDAVQNTLVLFFLQLVLYFPIPIALALLINSVVRPRVRALSQAILYLPHFFSWVLVIAVFQQLFGGAGILSQLLRQHGYDGLDIMTDPNTFKFLITAQSVWKDAGWGIIVFLAALSSVSPDLYEAAAMDGAGRWRRMWHITLPALRPVIALLLVLRVGDALTVGFEQILLQRDAVGPGAAEVLDTFVWWNGVRNQDFGYAAAAGLIKGVVSLGLVLAANKVAHLMGEQGVYKK
>NZ_CP041607.1|WP_054235310.1|7968399_7969335_+|carbohydrate-ABC-transporter-permease
MTAVIDKPVRGPSRWAAPPRPTWEEEPSKAGLAGKGLVLTLACLGIFFPLWIVIVTSLSSRKTIDEAGGLVMVPKGITFVAYKELLSGGQVTRASVISILITLVGTLFSMAVSVLCAYGLSRIGSLGHRWILLALLATMFFSAGLIPTYLLVQSLGLTDSYLALILPSAISVFNILVLRGFFMGISQELIDSARIDGAGDVRILWQIVMPLSRAVLAVITLFYAVGYWSAWFNASLYLSDQDMMPLQNVMIQLVQKQEAPVGLGQAIKTGQLSGLAVQMAVMVMALLPVAVLSPFVQRHFKKGMLTGAVKG
>NZ_CP041607.1|WP_143603072.1|7970630_7972610_+|beta-galactosidase
MPTLADATRGRILFGGDYNPEQWPEELWREDVRLMKEAGVNSVTVGVFSWAKLEPTPGAREFGWLDRLMDLLHENGVGVVLATPTSSPPPWMGRLHPETLPRDADGRVEWWGGRQHFAHSSAAYRRHAAAITEDLAARYGGHPALTMWHINNEYCTYDWGDEAAAAFRRWLQDTYGTLDALNTAWGTAFWSQGYDDWEGVLPPRHAHYMNNPTQVLDFKRFTSDALLECYLAERDIVARHTPHIPVTTNFMPFWQGQDAWAWAEREDVVSVDIYPDPRDPLGAQYGALIHDMTRSQAHGGPWMVMEQAAGPVNWRGVNHPKPRGLNRLWSLQAVARGADAVCYFQWRQSRQGAEKFHSGMVSHAGERGRTFQEVKRIGAELALLSDKVTGTRVVGADVAVLLDWNAWWASQQDGRLSCEVDHQSVVRAWHRALWEANTTTSFAHPEHDLSGYKLVVVPQLYLLTDRAIDNLVGYVRGGGTLVSGFLTGVADQDDRVRPGGMDERLRALFGIRTLHEWWPLDADEKVEAEGFRGTLWSEEIEAADDTYAVVRYKGGELDGLPAVLRKGRAWYLSTLPEPEALWPLLAGIAEDAGVRPPLDHLPADVEAVRRGELLFLLHHGRDTVTVPVPGRHRDLLTGEDVVDAVELGRYGVVVLEAAP
>NZ_CP041607.1|WP_143603073.1|7972606_7974880_+|hypothetical-protein
MSEPAGGPTDDPADGPTDAPVHGSIDAPVHGTWEPAPAARWEDAFLSGNGRHGVMVFGDPNDDRVIVNHHSLVRPNGSEHARPPELAERLRSVQDRLLAGDVDAGEDFTDGRPLLWVQPFHPAFQVRLRRAPRESRAYRREVDFTTGVVRAECGGRRGEVFVSRADDVIVQYVTEADLTVDVTLDHRLPGVPVDLGVGHGCVRTPEGALLTLRARYPGSERAYTGVTLAVVTGGRTLTAPPGIRVEGARSVLLLTRVRRHEGEWDTLAEARELRALLPDGDEDAYDRLLARHTALHRRAYLRAGLELGADPAERALPGSELVRRPKSRALLERLFAAGRYHLLSAAGMLPPRLTGLWTGDWDTAWSGAFTTDANVNLQTASAAAAALPEVSEAHAALIHGQLPHWRDNARAIFGARGVVAPAHTDGESGHIYHLSREYPLHVWTAGADWLLKPLVDHDETRGARDPRLAAALAEVARFYEDFLTRTDENGHVVIVPSYSPENRPATARWITLNAAMDLSAARHALRTAADHHPGPDAERWRALADRLPPHRVNADGALAEWAWPGLDDTYDHRHLSHLYGVWPLDEINPYDTPELAAAAHRALVLRGAENDSAHGHLHHALVAARLRDAARVAGALDNVLAGDFFHVSLMSGHYPNRHVYNADAAHTLPAVLIETLVHSTPGRLVLFPALPTAYPSGRLHGIRTRFGAEVDLTWSPEERTAVIRPTRSTRIDLRTSAGARPLSLSAGEDCVLTLGPQ
>NZ_CP041607.1|WP_143603074.1|7974915_7975629_+|hypothetical-protein
MAPRTLGRAAKALLAPALALGATVGLASAPAQAAVWNSCEQYGNTSLNGYTLYNNIWGSGAGSQCIWANSGTNWGVWANHPNTGGIKSYPNAKKVINKSITSLGSLTSGYNVTVPSSGAYNTSYDIWDTGYKYEIMLWVNKTGAVGPLGTSQGTLTLGGHTWTVYKGNNGSNDVFSFVRTSNSSSGTVDVLPILKWIKDTKGWFGNVTIGDLQFGFEITSSSGGLDFVTNSLSVSSS
>NZ_CP041607.1|WP_143603075.1|7975646_7976138_-|hypothetical-protein
MVYLLLLLVPGGLVAAFAFVGYCFGTLGRIGLRQADRVVWLRVVAALMGAATALLYVWGLAHLVGAVMDAAENGADSAPLRPCRAPGREQRAQDPGSVDYTVRYLPIRFVCETGDGEGHVTDAVPDYLNPGVLGFALAGAGCAGAARLISRRPGPRATREPSH
>NZ_CP041607.1|WP_143603076.1|7976254_7978306_-|glycoside-hydrolase-family-31-protein
MNQPAENQTQSGAVSLAQSSPTVGTFRERDGALEWSGRQETVRIEPWGPDAVRVRARLGGAVLEGLPGALLDEPQVTESTVKIQDGEGRLTVGALTVEVDAEGQVRFLRTADGTELLAEERAHFWWPGPRLYTPTGNGHHRLEQRFAAYEGEKLYGLGQHQHGLLDQKGAVLDLVQRNAEVTVPVLTSSRGYTFLWNSPAIGRVELAGNGTRWVADSARQLDYWITAGTPADAQRRYSAATGRTPMLPEWAAGFWQCKLRYRTQDELLDVAREYKRRGLSLSAIVCDFFHWTHLGDWKFDPAEWPDPAAMQRELAELGVKLVVSVWPSVSPLSENHPLMEQRGYFIGTQYGPMAHADWPDKEVASTVQVAFYDATNPEARDFLWSRVKDNYLDPYGISAFWLDACEPELKPGFQENLRYHAGPGLEVGNLYPRENARTFYEGMLAAGETEVVTLNRSAWAGSQRYGAALWSGDIGTDFATLRRQIAAGLNTALSGIPWWNTDIGGFHGGDPDDPAYREVMVRWFQFGALSPLMRLHGFRDPGMPLGPDMTGGPNEVWSYGEEVGAILEKYLRLRERLKPYVLDVMREAHEEGLPVMRPLFLEFPEDHAAWSVDDSYLFGSDLLVAPVLTAGATVRTAYLPAGARWTDAWTGETYEGGAAVTVDAPLDRIPLFLRDGARLPVAE

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Crispr_ID: NZ_CP041607_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_17

7990977-7991117

Orphan

Consensus_repeat	Method
ACGCACCCGCAGACAAGCGATCCGGGGCCGTCGTCGTATCCGGGGCGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_17

>merge|NZ_CP041607|17|7990977-7991117|CRISPRCasFinder
ACGCACCCGCAGACAAGCGATCCGGGGCCGTCGTCGTATCCGGGGCGCAGTCCGGCCCCAAGGGGCGCGGGGAACTGCGCGCCCAGCCCTCACGCACCCGCAGACAAGCGATCCCGGGCCGTCGTCGTATCCGGGGCGCAG

>NZ_CP041607|17|16|7990977-7991117|CRISPRCasFinder
ACGCACCCGCAGACAAGCGATCCGGGGCCGTCGTCGTATCCGGGGCGCAG	TCCGGCCCCAAGGGGCGCGGGGAACTGCGCGCCCAGCCCTC
ACGCACCCGCAGACAAGCGATCCCGGGCCGTCGTCGTATCCGGGGCGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_097289235.1\|7991370_7992219_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379120
NZ_CP041607.1\|WP_143603080.1\|7993044_7994742_+\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236405
NZ_CP041607.1\|WP_143603083.1\|7996790_7998050_+\|NADH-quinone-oxidoreductase-subunit-E	unknown	unknown	gnl\|CDD\|224806
NZ_CP041607.1\|WP_143603077.1\|7979840_7980647_+\|endo-1,4-beta-glucanase	unknown	unknown	gnl\|CDD\|366751
NZ_CP041607.1\|WP_054235302.1\|7982846_7983332_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603078.1\|7983348_7986117_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP041607.1\|WP_143603081.1\|7995220_7996198_+\|FAD:protein-FMN-transferase	unknown	unknown	gnl\|CDD\|376782
NZ_CP041607.1\|WP_097286450.1\|7998051_7998297_+\|ferredoxin	unknown	unknown	gnl\|CDD\|379198
NZ_CP041607.1\|WP_054235298.1\|7988100_7989405_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100084
NZ_CP041607.1\|WP_054235300.1\|7986147_7986600_-\|lamin-tail-domain-containing-protein	unknown	unknown	gnl\|CDD\|376421
NZ_CP041607.1\|WP_097286444.1\|7980790_7982743_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173850
NZ_CP041607.1\|WP_143603079.1\|7986820_7988104_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl\|CDD\|235472
NZ_CP041607.1\|WP_097286451.1\|7999341_7999833_-\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|373114
NZ_CP041607.1\|WP_060901179.1\|7978488_7979502_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP041607.1\|WP_143603082.1\|7996194_7996794_+\|ferric-reductase	unknown	unknown	gnl\|CDD\|366815
NZ_CP041607.1\|WP_097286446.1\|7989579_7990737_+\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|234737
NZ_CP041607.1\|WP_060901173.1\|7992402_7992972_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223532
NZ_CP041607.1\|WP_143603076.1\|7976254_7978306_-\|glycoside-hydrolase-family-31-protein	unknown	unknown	gnl\|CDD\|224418
NZ_CP041607.1\|WP_097289236.1\|7998309_7999251_-\|kinase	unknown	unknown	gnl\|CDD\|309685
NZ_CP041607.1\|WP_143603084.1\|7999829_8000372_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375354

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_097289235.1\|7991370_7992219_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379120	pfam13312, DUF4081, Domain of unknown function (DUF4081). This domain is often found N-terminal to the GNAT acetyltransferase domain, pfam00583 and FR47, pfam08445.	1.29199e-48
NZ_CP041607.1\|WP_143603080.1\|7993044_7994742_+\|proline--tRNA-ligase	gnl\|CDD\|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NZ_CP041607.1\|WP_097286444.1\|7980790_7982743_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	1.78045e-88
NZ_CP041607.1\|WP_143603083.1\|7996790_7998050_+\|NADH-quinone-oxidoreductase-subunit-E	gnl\|CDD\|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	1.09123e-42
NZ_CP041607.1\|WP_143603077.1\|7979840_7980647_+\|endo-1,4-beta-glucanase	gnl\|CDD\|366751	pfam01670, Glyco_hydro_12, Glycosyl hydrolase family 12.	7.08277e-29
NZ_CP041607.1\|WP_143603082.1\|7996194_7996794_+\|ferric-reductase	gnl\|CDD\|366815	pfam01794, Ferric_reduct, Ferric reductase like transmembrane component. This family includes a common region in the transmembrane proteins mammalian cytochrome B-245 heavy chain (gp91-phox), ferric reductase transmembrane component in yeast and respiratory burst oxidase from mouse-ear cress. This may be a family of flavocytochromes capable of moving electrons across the plasma membrane. The Frp1 protein from S. pombe is a ferric reductase component and is required for cell surface ferric reductase activity, mutants in frp1 are deficient in ferric iron uptake. Cytochrome B-245 heavy chain is a FAD-dependent dehydrogenase it is also has electron transferase activity which reduces molecular oxygen to superoxide anion, a precursor in the production of microbicidal oxidants. Mutations in the sequence of cytochrome B-245 heavy chain (gp91-phox) lead to the X-linked chronic granulomatous disease. The bacteriocidal ability of phagocytic cells is reduced and is characterized by the absence of a functional plasma membrane associated NADPH oxidase. The chronic granulomatous disease gene codes for the beta chain of cytochrome B-245 and cytochrome B-245 is missing from patients with the disease.	5.14322e-05
NZ_CP041607.1\|WP_143603078.1\|7983348_7986117_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP041607.1\|WP_143603081.1\|7995220_7996198_+\|FAD:protein-FMN-transferase	gnl\|CDD\|376782	pfam02424, ApbE, ApbE family. This prokaryotic family of lipoproteins are related to ApbE from Salmonella typhimurium. ApbE is involved in thiamine synthesis. It acts as an FAD:protein FMN-transferase, catalyzing the attachment of an FMN residue to a threonine residue of a protein via a phosphoester bond in such bacterial flavoproteins.	6.03509e-46
NZ_CP041607.1\|WP_097286450.1\|7998051_7998297_+\|ferredoxin	gnl\|CDD\|379198	pfam13459, Fer4_15, 4Fe-4S single cluster domain.	4.97328e-11
NZ_CP041607.1\|WP_054235298.1\|7988100_7989405_+\|site-2-protease-family-protein	gnl\|CDD\|100084	cd06163, S2P-M50_PDZ_RseP-like, RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog RseP is involved in the sigmaE pathway of extracytoplasmic stress responses. Also included in this group are such homologs as Bacillus subtilis YluC, Mycobacterium tuberculosis Rv2869c S2P, and Bordetella bronchiseptica HurP. Rv2869c S2P appears to have a role in the regulation of prokaryotic lipid biosynthesis and membrane composition and YluC of Bacillus has a role in transducing membrane stress. This group includes bacterial and eukaryotic S2P/M50s homologs with either one or two PDZ domains present. PDZ domains are believed to have a regulatory role. The RseP PDZ domain is required for the inhibitory reaction that prevents cleavage of its substrate, RseA.	2.9615e-45
NZ_CP041607.1\|WP_054235300.1\|7986147_7986600_-\|lamin-tail-domain-containing-protein	gnl\|CDD\|376421	pfam00932, LTD, Lamin Tail Domain. The lamin-tail domain (LTD), which has an immunoglobulin (Ig) fold, is found in Nuclear Lamins, Chlo1887 from Chloroflexus, and several bacterial proteins where it occurs with membrane associated hydrolases of the metallo-beta-lactamase,synaptojanin, and calcineurin-like phosphoesterase superfamilies.	8.84356e-25
NZ_CP041607.1\|WP_060901173.1\|7992402_7992972_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	2.83342e-06
NZ_CP041607.1\|WP_143603079.1\|7986820_7988104_+\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl\|CDD\|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP041607.1\|WP_097286451.1\|7999341_7999833_-\|ferritin-like-domain-containing-protein	gnl\|CDD\|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	5.13819e-31
NZ_CP041607.1\|WP_060901179.1\|7978488_7979502_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.86494e-69
NZ_CP041607.1\|WP_097286446.1\|7989579_7990737_+\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl\|CDD\|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NZ_CP041607.1\|WP_143603076.1\|7976254_7978306_-\|glycoside-hydrolase-family-31-protein	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	9.59459e-172
NZ_CP041607.1\|WP_097289236.1\|7998309_7999251_-\|kinase	gnl\|CDD\|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	2.99381e-67
NZ_CP041607.1\|WP_143603084.1\|7999829_8000372_-\|hypothetical-protein	gnl\|CDD\|375354	pfam17818, KCT2, Keratinocyte-associated gene product. This entry includes Keratinocyte-associated transmembrane protein 2 found in humans. Functional studies show that KCP2 localizes to the endoplasmic reticulum, consistent with a role in protein biosynthesis, and has a functional KKxx retrieval signal at its cytosolic C-terminus.	0.00501074

>NZ_CP041607.1|WP_097286446.1|7989579_7990737_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MTAISLGMPSVPTKLAERRKSRQIQVGTVAVGGDAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIKQFDDQVKEIARAAKDTGTPIRIGVNAGSLDKRLLQKYGKATPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMVNAYRQLAAACDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEVKVGLQILESLNLKQRGLEIVSCPSCGRAQVDVYKLAEEVTAGLTGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEAMKLAEQMEADGIASGEPSVSVAG
>NZ_CP041607.1|WP_054235298.1|7988100_7989405_+|site-2-protease-family-protein
MTTLMMILGIVVFAVGLLISIAWHELGHLSTAKLFGIRVPQYMVGFGPTIWSRKKGDTEYGVKAVPLGGYIRMIGMFPPGPDGRIEARSTSPFRGMIEDARSAAFEELQPGDETRLFYTRKPWKRVIVMFAGPFMNLVLAVAIFLGVMMTFGVQTQTTTVGKVSDCVIQQSENRSKCAASDQAAPAKAAGLKGGDKIVAFNGKVIDDWAALQSDIRSNPGKDVTLTVERGGQKVDLTAHLIKNQVSKTDGNGGYVEGKYVYAGFLGFTPASGIVQQSFGQSVNRMGDMMQNGVESLVSLPGKIPDLWNAAFGDGPRKADSPMGVVGAARIGGDVFTLDIPASQQVAMMLLLVAGFNLSLFLFNMLPLLPLDGGHIAGALWESLRRNAAKVLRRPDPGPFDVAKLMPVAYVVAGIFVCFTILVLIADVVNPVKIS
>NZ_CP041607.1|WP_143603079.1|7986820_7988104_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MSDSPAPLADPHLVFDPVDGVRDVVILGSTGSIGTQAIDLVLRNPDRFRVTALSAAGGRVALLAEQAHRLRVRTVAVAREDVVPALREALTAEYAPGETLPEILAGADAATQLAASDCHTVLNGITGSIGLAPTLAALEAGRTLALANKESLIVGGPLVKALAKPGQIIPVDSEHAALFQALAAGTRADVRKLVVTASGGPFRGRTKAELANVTPAEALAHPTWAMGPVITINSATLVNKGLEVIEAHLLYDIPFDRIEVVVHPQSYVHSMVEYTDGSTLAQATPPDMRGPIAIGLGWPERVPDAAPAFDWTKASSWEFFPLDNDAFPSVGLARHVGQLAGTAPAVFNAANEECVDAFLNGALPFNGIMETVTRVVEEHGTPGTGTSLTVADVLEAETWARARARELTAQTAPTVPMAQTTTAEARA
>NZ_CP041607.1|WP_054235300.1|7986147_7986600_-|lamin-tail-domain-containing-protein
MRIRAALPALAGAVALTGTFLLSTPAQAAGGVTIYHVWFDSPGSDNRSNASLNAEWVQIKNTSSTAISLKGWILKDVSNHRYTFPNVKIGAHKTMKVHTGSGRDTAGDKYQNRRAYVWNNTSDTATLTKANGGKVDACSWTTRDPSDKYC
>NZ_CP041607.1|WP_143603078.1|7983348_7986117_+|preprotein-translocase-subunit-SecA
MPGKGLDVITGRIMRAGEGRVLRRLQRVVDQVNSLDEEFRALSDEDLQSLTPEFQQRHADGESLDDLLPEAFATMREAARRTLGMRHFDVQVMGGAALHLGNIAEMQTGEGKTLVATLPVYLNALAGKGVHLVTVNDYLAERDAEWMGRAYRFLGLTVGVIKSDSTPAARRAQYACDITYGTNTEFGFDYLRDNMAWSRDELVQRGHHFAIVDEADSILIDEARTPLIISGPADQPTQWYEAFAGLVRRMKGVRVQEELFTRPAEKEELTALRATYDYEYDPKKRTVAILDRGVEYLQDQLGIESLYESDHTSLIGHLNNALKAKEHFKRDKDYVVVDGEVLIVDEHTGRILAGRRYNEGLHQAIEAKEGVTIKDENQTLATITLQNFFRLYEKLAGMTGTAMTEAAEFHQIYQLQVVPIPTNRPPRRADDPDQIYRTADAKYAAIVEDIAERHAQGQPILVGTTSVEKSELLSALLRKRGIRHEVLNAKNHQREAQIVAQAGRKGAVTVATNMAGRGTDIMLGGNPESLIAAELEKSALTEEEHPDACREVRERVTAAVGAAYEEVKELGGLYVLGTERHESRRIDNQLRGRSGRQGDNGASRFYLSLEDDLMRLFRAQVVDRVMAMANVPDDIPIENKMVTRAIASAQAQVEQQHFESRKDVLKFDEVLNRQRTLIYAERRRVLAGEDLREQLLHFMDDTVRAYIGQETGEGFPEEWDLERLWGAFAQLYPVRVTIEGLEEAAGDRANLTAEDLVEAVTRDIHDRYEDREAELGAEALRDLERLVVLNVLDRKWREHLYEMDYLRDGIGLRWTLGREPIVEYEREGFDMYGAMTDAIKEESVGYVFNLDASGGPGALERRDRVEDLHFTAPTMDTAEGVVEGGFAPADADAPATASASAPAPSRGGARPGRSKARRRRKR
>NZ_CP041607.1|WP_054235302.1|7982846_7983332_+|hypothetical-protein
MRQGIGEEHGHGLSAQLTRARAEARLQLDEPDLVRALRTVRKEVRPLAQKLREVAPETFEAHRDALAVLLNDCALALVDTEPRPPVPSFDAVRIRRIDLRDVDGLLDAGRPGERPVIQQLFKSALDVVDDPVLREVIKANQQGVHILQRANHWIRLLADAV
>NZ_CP041607.1|WP_097286444.1|7980790_7982743_+|acyl-CoA-dehydrogenase
MRGEVSLMSATPHQPTVTEREARQVAEAAREQDWRKPSFAKELFLGRFRLDLIHPHPMPAEDDVQRGEEFLAKLRDFCETKIDSARIEREAQIPDEVIDGLKDIGALGMKIDTKYGGLGLTQVYYNKALALVGSANPAIGALLSAHQSIGVPQPLKLFGTQEQKDVFLPRCARTDISAFLLTEPDVGSDPARLATSAVPDGDDYVLDGVKLWTTNGVVADLLVVMARVPKSEGHKGGITAFVVEAGSEGITVENRNAFMGLRGLENGVTRFHQVRVPAANRIGPEGAGLKIALTTLNTGRLSLPAMCVGAGKWCLKIAREWSAAREQWGKPVALHEAVGAKISFIAATTFALEAVVDLSSQMADENRNDIRIEAALAKLYGSEMGCLMADELVQIRGGRGFETAASLAARGERAVPAEQILRDLRINRIFEGSTEIMHLLIAREAVDAHLSVAGDLIDPDKSLSDKAKAGANAGVFYAKWLPKLVAGPGQLPRSYGEFNRHVDLSPHLRYVERNARKLARSTFYAMSRWQGRMETKQGFLGRIVDIGAELFAMSAACVRAEHLRLTGQHGREAYQLADAFCRQSRIRVDELFGRLWSNTDDLDRKVVKGVLAGTYEWLEQGVIDPSGDGPWIADATPGPSRKENVHRPIR
>NZ_CP041607.1|WP_143603077.1|7979840_7980647_+|endo-1,4-beta-glucanase
MQHRRPRLSKKAKTMLAGTVALAAAAGVTVAQAGEADKKCGAFDTVTMGKYYVNNNLWGQDDGTGTQCVWDTSRSGDTVGWGTNYTWTSKAGKENSVKSYASTVLGWHWGWKTDKAATELPVRVGDRKPVRTSWEFSVGSDPGTMNVAYDLWLHAKGNADWQDRPTDEVMVWLNRQGGAGPLGTKYGSVSLDGAMWDIYQGDIGWKVYSFVRRANTTKASLDLDDFTQALVRRKLLGNDKYLSGIESGSEVFRGSGRLDTKAYSVDIG
>NZ_CP041607.1|WP_060901179.1|7978488_7979502_-|LacI-family-transcriptional-regulator
MVTLAEVAQHAGVSASTVSYVLSGKRSISAGTRQRVERSIQELGYHPNAGARALASSRSNIIALMVPLRTDMYVPVMMEIAIAVATHARTHGYDVLLLTGEEGPDAVRRVTGSGLADAMILMDVELDDERLPLLRQTDQPSVLIGLPADTSGLTCVDLDFGATGALCAEHLALLGHRDIAVIGEAPAVYERHTGFAERTLDGLRSRSRELGLRVLHRPCEGGYDAMALTLARILDERPGTTGFVVQNESAVEPLLALLRQQGRAVPEDVSVIAICPDQVATQASVRLTSVAIPAQEMGRLAVEHLIAKLEGHGKDEVVLIAPELTVRASTGPAPTAA
>NZ_CP041607.1|WP_143603076.1|7976254_7978306_-|glycoside-hydrolase-family-31-protein
MNQPAENQTQSGAVSLAQSSPTVGTFRERDGALEWSGRQETVRIEPWGPDAVRVRARLGGAVLEGLPGALLDEPQVTESTVKIQDGEGRLTVGALTVEVDAEGQVRFLRTADGTELLAEERAHFWWPGPRLYTPTGNGHHRLEQRFAAYEGEKLYGLGQHQHGLLDQKGAVLDLVQRNAEVTVPVLTSSRGYTFLWNSPAIGRVELAGNGTRWVADSARQLDYWITAGTPADAQRRYSAATGRTPMLPEWAAGFWQCKLRYRTQDELLDVAREYKRRGLSLSAIVCDFFHWTHLGDWKFDPAEWPDPAAMQRELAELGVKLVVSVWPSVSPLSENHPLMEQRGYFIGTQYGPMAHADWPDKEVASTVQVAFYDATNPEARDFLWSRVKDNYLDPYGISAFWLDACEPELKPGFQENLRYHAGPGLEVGNLYPRENARTFYEGMLAAGETEVVTLNRSAWAGSQRYGAALWSGDIGTDFATLRRQIAAGLNTALSGIPWWNTDIGGFHGGDPDDPAYREVMVRWFQFGALSPLMRLHGFRDPGMPLGPDMTGGPNEVWSYGEEVGAILEKYLRLRERLKPYVLDVMREAHEEGLPVMRPLFLEFPEDHAAWSVDDSYLFGSDLLVAPVLTAGATVRTAYLPAGARWTDAWTGETYEGGAAVTVDAPLDRIPLFLRDGARLPVAE
>NZ_CP041607.1|WP_097289235.1|7991370_7992219_+|GNAT-family-N-acetyltransferase
MLTQTTTRVLEPSDLDAALAVLDRDPVANAFVASRVQVAGLDPWRLGGEMWGWYEDGMLRSLCYAGANLVPICATPRAVRGFADRARRAGRRCSSIVGPVEATAQLWRLLEPSWGPAREVRAHQPLMVTDRLPADIAPDPYVRRIRKDEMETIMPACVAMFTEEVGVSPLAGDGGLLYQARVAELVGTGRSFARLDQNGKVVFKAEIGAATRQACQVQGVWVDPEYRGQGLAAPGMAAVMRYALADIAPLVSLYVNDFNTPARATYHRVGFQEVGAFMSVLF
>NZ_CP041607.1|WP_060901173.1|7992402_7992972_+|GNAT-family-N-acetyltransferase
MLRFPGQGPRNPDDVVVGPLDLAARVDEALAVQALAFGLGADEVAVRRQIVLRHLTYPGARALGATTVDGRLVGFVYGMPNDRTHWWSTVVEPYLRAQGRDAWLDHSFVITELHVHPHYQNHGVGRSLITGITDSATEPRSILSAIDTDSPARGLYRSLGYEDLARQVLFPSAPKPYAVMGAPLPLRRR
>NZ_CP041607.1|WP_143603080.1|7993044_7994742_+|proline--tRNA-ligase
MAQVQRMSRLMVKTLRDDPADAETLSHKLLVRAGYVRRNSAGIWTWLPLGKKVLDNISRVVREEMDAIGAQEVLLPALLPKEPYEASARWEEYGDLLFRLKDRKGGEYLLGPTHEEIFTLVVKDQVASYKDLPVMLYQIQTKYRDEARPRSGVLRGREFQMKDSYSFDTTDEGLAHSYALHRAAYQKIFARLGLDYRIVSAVSGAMGGSASEEFLAPAAAGEDTFVDCPSCDYAANTEAVTFALKPVDGSGVGPVEELDTPDTPTIETLAEHLGVPASATLKNLLVKVDGEIVAVGVPGNREVDLGKLGEHLAPAVVELVTAEDFEGRGDLVRGYVGPQGLEKVRYIADPRVAPGTAWITGANKVNTHAKNVVASRDFEVDDYLDVVVVEEGDPCPKCGTGLKLDRAIEIGHIFQLGRKYADTFQLDVLGQQGKPVRVTMGSYGIGVSRAVAALAEQSADEQGLCWPKEIAPADVHVVAAGKALQTELALDVSEKLGAAGVRVLVDDRAGVSPGVKFTDAELIGVPKILVAGRRSAEGVLELKDRRTGEREELTVDEAIARLAAE
>NZ_CP041607.1|WP_143603081.1|7995220_7996198_+|FAD:protein-FMN-transferase
MATATRRTTAAADWRALGTSVRLVTTDPALLDSCNLLLARHLAEVDAACSRFRQDSELVALDQARGRPVRVSPLLAEALAVALRAAAATDGAVDPTVGSAIGALGYDRDFRLIQDDGRPIRLTVRPVPGWRAVTLDRATDTVTVPAGVRLDLGATAKAWAADKAAARLAEAAGCGVLVSLGGDTAVAGEPPAGGWRVRVQDATGPVDETPAPGTYATVSIRSGGLATSGTTSRRWRRGAHDLHHIVDPYTGLPAETPWRTVSVAAATCADANAAGTAALVKGAGAQQWLAGLGLPARLVANDGTVVTTPGWPPSAPAWSGPEAAA
>NZ_CP041607.1|WP_143603082.1|7996194_7996794_+|ferric-reductase
MSDSALLWYANRATGAVSLVLFTVVVLLGIAVRLRGRLPGLPRFGTVRLHRTLSLSAVVFLALHITAAVVDSYVSISLLDVLVPFASTYQPLWLGLGTVALDLMLAVLITSLLRARIGHRAWRAVHWLAWASWPIALIHGIGIGTDTGAGWMLWLTLSCLAAVLTAFGIRVAHAARASGLTPSTLLRTAESRTPEGARP
>NZ_CP041607.1|WP_143603083.1|7996790_7998050_+|NADH-quinone-oxidoreductase-subunit-E
MTTTTTVTATATATVATTSTDIYMPPRLLAPGGAPAGFSTHEQRYGPVAHGDPAQLLRTLAESGLTGRGGAAFPTYRKLVSVAEAGRRTGRTPVVVANGAEGEPASAKDKTLLRLSPHLVLDGLQLVAELVGAGEAYLAVEDHATPLEAALAERRDPLRVRTVRVPKRFLSGQSSALTQYVSGHAALPRHQRPPVREQGAHRAPTLVQNVETLAHLALIARYGADWFRSLGTPAEPGSALCTVHVPGRGIRVLEAPFGMPLHRLLPLGGIGAVLVGGYHGTWLPAAEAATRTLTVADLGAGVLAALPTSRCGLAETARVLRYLALESAGQCGPCLNGLPRIAAAFQTLATPGPQGGTREDIARWAGLVEGRGACHHPDGTVRLVRSALTTFAAELDAHAAGHCTATDHSPLLPVPANRN
>NZ_CP041607.1|WP_097286450.1|7998051_7998297_+|ferredoxin
MARHAHRTDRLDRTHRLEVDWTACQAHGLCAELLPEHITLDEWGYPLLGEAPLPPTTLKRARRAAADCPVLALKLATAQGS
>NZ_CP041607.1|WP_097289236.1|7998309_7999251_-|kinase
MAFEPPRRLVRALGETQRSGSNGSGGSNGTGEWLDKLPVLAQQAVDLRELTVERVQAPGGRSSLVLLVRQADGTPAVLKLAPPRARPESERAALAHWDGRGAVQLLNPADAQGDTHGVLVLERLRPDLSVRSLPEAKALLEAAGTLRRLWVEPPATHVFETVAERTGRQAEAMRAAASADTEVAPLVDAALAAREELLAGPPEERLLHGTFRQSKVLAGERMPWLAVGPDPVVGECAFDLARLVRDRVEDLIASPSGSSITRRRVKRLAESLEVDQDRLRGWTLFRAVESGVRAGRVGRPQDAELLLEFAGWL
>NZ_CP041607.1|WP_097286451.1|7999341_7999833_-|ferritin-like-domain-containing-protein
MSTTEDTKSAKAAELGALQAALAAEHAAVYGYGVVGGRIDEARRGEARSAYDAHRARRDELARAVRDLGGRPEVSAAAYALPFAVKDSAAAVQLAADLEERVAGVYSDLVRASSGDRRRSAAEALREAAVRAVRWRGESVAFPGLAERAAPSATPAAATPSPS
>NZ_CP041607.1|WP_143603084.1|7999829_8000372_-|hypothetical-protein
MPFTLPPRTPSGPRRRSLFASAAGAFVLVGCSAPEPSTVTTVRSPSAADLTRARAARDSESLAARYAAVITAHPPLAGRLKPLRAEVVRHAQAFGGSGTAGSRPSASGSPSASASAHPSPSPTVPAQEKDALADLATAERTLADQRTKALLTVPGELARLLASVAAAGAAHAFLLTEGAK

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Crispr_ID: NZ_CP041607_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_18

8584391-8584475

Orphan

Consensus_repeat	Method
GAGGACGGCGACAGCTGGTGACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_18

>merge|NZ_CP041607|18|8584391-8584475|CRISPRCasFinder
GAGGACGGCGACAGCTGGTGACCCGCATCCCGTATCCCGTCCCGGCGCACCCGTACGACCGAGAGGACGGCGACCGCTGGTGACC

>NZ_CP041607|18|17|8584391-8584475|CRISPRCasFinder
GAGGACGGCGACAGCTGGTGACC	CGCATCCCGTATCCCGTCCCGGCGCACCCGTACGACCGA
GAGGACGGCGACCGCTGGTGACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143603285.1\|8586601_8588728_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NZ_CP041607.1\|WP_060898396.1\|8575261_8575810_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603287.1\|8590182_8590953_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603280.1\|8568024_8569536_+\|cellulose-binding-protein	unknown	unknown	gnl\|CDD\|366161
NZ_CP041607.1\|WP_143603286.1\|8589083_8590127_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238697
NZ_CP041607.1\|WP_143603291.1\|8597767_8600485_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|369272
NZ_CP041607.1\|WP_143603288.1\|8590920_8592342_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223708
NZ_CP041607.1\|WP_097286721.1\|8564311_8565319_+\|hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240644
NZ_CP041607.1\|WP_107469532.1\|8575942_8578183_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP041607.1\|WP_143603292.1\|8604388_8604757_-\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274925
NZ_CP041607.1\|WP_143603290.1\|8593455_8596500_-\|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl\|CDD\|335469
NZ_CP041607.1\|WP_143603281.1\|8570774_8571647_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603282.1\|8571652_8574175_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054236962.1\|8600731_8601841_+\|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl\|CDD\|234988
NZ_CP041607.1\|WP_143605689.1\|8602316_8603717_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225080
NZ_CP041607.1\|WP_143603289.1\|8592412_8593426_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370993
NZ_CP041607.1\|WP_143605688.1\|8569946_8570660_+\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NZ_CP041607.1\|WP_060901056.1\|8566400_8567747_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_097289273.1\|8574209_8575265_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603283.1\|8578319_8581793_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372732

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143603285.1\|8586601_8588728_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	2.77647e-06
NZ_CP041607.1\|WP_143603292.1\|8604388_8604757_-\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274925	TIGR04023, Pyridoxamine_5'-phosphate_oxidase, PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. This subfamily within the PPOX family occurs in at least 19 distinct species of F420 producers and is likely to bind F420 rather than FMN. The member OxyR was shown to use F420 to catalyze a C5a-C11a reduction in oxytetracycline biosynthesis. [Unknown function, Enzymes of unknown specificity].	1.32343e-61
NZ_CP041607.1\|WP_143603280.1\|8568024_8569536_+\|cellulose-binding-protein	gnl\|CDD\|366161	pfam00553, CBM_2, Cellulose binding domain. Two tryptophan residues are involved in cellulose binding. Cellulose binding domain found in bacteria.	2.68127e-30
NZ_CP041607.1\|WP_143603291.1\|8597767_8600485_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	5.00278e-56
NZ_CP041607.1\|WP_143603288.1\|8590920_8592342_-\|radical-SAM-protein	gnl\|CDD\|223708	COG0635, HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism].	2.69618e-45
NZ_CP041607.1\|WP_097286721.1\|8564311_8565319_+\|hydroxyacid-dehydrogenase	gnl\|CDD\|240644	cd12167, 2-Hacid_dh_8, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.61324e-137
NZ_CP041607.1\|WP_107469532.1\|8575942_8578183_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	2.01808e-10
NZ_CP041607.1\|WP_143603290.1\|8593455_8596500_-\|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.81038e-47
NZ_CP041607.1\|WP_143603286.1\|8589083_8590127_+\|hypothetical-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	1.77768e-30
NZ_CP041607.1\|WP_054236962.1\|8600731_8601841_+\|ribosome-small-subunit-dependent-GTPase-A	gnl\|CDD\|234988	PRK01889, PRK01889, GTPase RsgA; Reviewed.	0
NZ_CP041607.1\|WP_143605689.1\|8602316_8603717_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	1.61892e-57
NZ_CP041607.1\|WP_143603289.1\|8592412_8593426_-\|hypothetical-protein	gnl\|CDD\|370993	pfam10343, Q_salvage, Potential Queuosine, Q, salvage protein family. Q_salvage proteins occur in most Eukarya as well as in a few bacteria possible via horizontal gene-transfer. Queuosine (Q) is a chemical modification found at the wobble position of tRNAs that have GUN anticodons. Most bacteria synthesize queuosine de novo, whereas eukaryotes rely solely on salvaging this essential component from the environment or the gut flora. The exact enzymatic function of the domain has yet to be determined, but structural similarity with DNA glycosidases suggests a ribonucleoside hydrolase role.	6.63381e-06
NZ_CP041607.1\|WP_143605688.1\|8569946_8570660_+\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.34113e-31
NZ_CP041607.1\|WP_143603283.1\|8578319_8581793_+\|hypothetical-protein	gnl\|CDD\|372732	pfam13809, Tubulin_2, Tubulin like. Many of the residues conserved in Tubulin, pfam00091, are also highly conserved in this family.	4.75557e-73

>NZ_CP041607.1|WP_143603283.1|8578319_8581793_+|hypothetical-protein
MKIFQPMLFVGLGGTGGLVGAELERKLRAELCGPDGVALSHLSGHAPYQLPDCLQFVYADYSESDLQRLPQFNVDPSLRAAYSRTSRATHNLLPNFDASPELTKMLRASLRDEVADWLPPRIDEPKVTPLHNGAGQLPTVGRAALFATLRHSLAPVLEPLLQAIDAIAKSAGELAELGGGKVNGCDVFVAFSVAGGTGAGIFLDYLHLINHAFQLRRFDGVKIYPLVVMPSSFSSAGGGGREAELNAARALVDLFRLVDAQNAPSEGTEIGDLDLDLDSGLGIRYPGTTPIRLRTGILPTAFLFSPTAGIRQDDLRRSIVSLVMSLIGTELGDSRPRGRATATDDDFQTFAASFINRGVHRSAVSPTGIGRQGVSTSLVASMTAPMDQLADLVAGRLLREAVTDLVERPRTALRDNAVPLIRQLFADSHLEELWERAQLAVPEPDPLPRGGKAIEQALGERLTDMQRLLSDLQSIADRQAASMADRFAPRPAIDKLLQSVDPFLAERIVRGVQDSDEPIARLGFLGMLDSRSRAPQRPPGVTDQPPKTPRIKGRLAGMSPARWGDDDVQAALQEQDLWYQWRSRTVWHEAWREQQQQWQPPAATAGADLGRLVNAFRKHSDQERKVSAQKGLELYEDRTGISYLLPPQRTLNHFYEDVVTRLIRREGMRENDDEAALLLRMIDGDTWREVHTLSRRNPDNAVAVVKAQLEGRITRLFAESGEHLEERPLLPAMGTLLAAAAGDADAADQVSKEALDLFGRKLTGLLPVGFTPEGTGPLRVLVTHPRVQAVEEVQEYLGKALRLPSDAKNSVEYRGVESDSVTVVLFRSEMSLTQVPEARKVLRQWARAKDSEQAQDVLRWRQRLGYRDSWMVSSEEDRRVILHRLLCCMWNGQVDVVDGDPASPERLRLRLFPEKGAHVPGVRLRLGDFPGGVSSWAELLRSYERWTVLDDERTVEDYCRELMGAQPLGLARSASEPHPLFVELVEKTAPRQLELLADRRERGGERVEGWVRPLWEFWAKTLPAALDTEFGDQRAVQPTLRTLLEHVRGGTPAQRVRKEVPEPRRAVADEDDWGTAPRASFDKYPSGAEERPRRASVDDYDDGYDADRGDRGDRVNGRSGGADRPSVPWDEPGDPGPYGDDGERERSRRNPWDGDPE
>NZ_CP041607.1|WP_107469532.1|8575942_8578183_+|VWA-domain-containing-protein
MAVLVSLLAPAGHDPVPAADSEPAFPAVNYSIAVDESASLAPEDMKAEKAAAARIALGDVSSSSHATVFGFAAAESDAQRAVDPVCPRTTLDAAGRETVGTCVDKLRGRTKNEGTGTDFPSAIRQGVHDLTTGTDPSQPRVLFLLTDGKLDVQDSPKYGDPAHRKDEGEQQLTQELENAAAQHVQIWPLGFGPDPDKAQLDRIAAGGYQKGCVELPSARPSAGKVSGAKDVGPVLEKIFAAAHCLRHEQGPSKRPPATLEIGISPLATVGSIVVDKGDPQVKITYLDPNGHQVPTTGTYRKSGFELAGGSGTVEALKIVDPVPGTWRVKAEAPEGHRSLPVAVSVLWQGELRGAITMDPPSPQAGEKVTVTMRLQTREGYEIKDARDYEGLRVRSELTGDGFDPLALRLTDDGQGPDSKASDGSFTGSVEIPKSADGALKVSGTLTASGLSADTRSEGGQIAPGALPVTTALELPTANTHPGSTVTGTLAVHNTSDTPHTLRLSVADLKSGLLTLTPAEIQVKPGESGTRKITVEVAPRDVFGDRLGDGGLQLGGTVTVVDTTDHDRTLVRTPLSVRVTPEPGVWAKYWWAFVSAAALIALATVAVLAWLRQRRTRRDPFGLVLRLVSAEGDVLGEHLAGHGHKQWYEFAVVEPHRSPRIERRAHGPYAVQRSPEGGAVLRKRGGGRTPLPARGQVQLTDTLSLALGEDTRASKVRRPRPSARTTAGSTTSATGTGESGSSYGSYL
>NZ_CP041607.1|WP_060898396.1|8575261_8575810_+|hypothetical-protein
MTGDGPARTSPDPVGPVPDGGPHGSDRGERIAERLLSTVREDLGRADAKAAVLLSGTLALPAFLIGRHGPPDWRGLADVTLILASVLWVVAVTALVGALMPRTRTVRGRDGVTYFGDLLAPRDLAGLSADVTEAGRDTAGWLLVQAVDVSSILSAKYRAIRWGVGSLAPSTALALAWSLTAR
>NZ_CP041607.1|WP_097289273.1|8574209_8575265_+|hypothetical-protein
MRARKAAAGPAGPFLREYAPTGGSPQVSAQKASVLFYRNGGYSVVTVSGVRHVDKRALARPYTVCEIALGTYVTTLQMELPAAGGTTFFKAEVDIHWTVTDPHLTATEVVTDVAQRLTAPVLERLREVSSAYRVTQAEQADRAITLECAGGRWADLGTELGMRVRLYVRLRVDDRTIEHMDGIRDAHASAEVTRVHQAAFRKMLQGGELEQLSYMLAAEPEAAKDFLEKIRQEGRQDEKERVDRLFAMVASGQIQSNDMETQALNLLNQGRHPLQGPIGSLPARRETPQLAPAADEPFTPDWVADEPPSRADRGPRAREPYQGDPQDAEPEPPRRRTRSRDDGWSWAEEDR
>NZ_CP041607.1|WP_143603282.1|8571652_8574175_+|hypothetical-protein
MTDDQQAGGGAEPAPRKGADARSPEADGKARNDPPRADEGKAEGDEGAAGNDAPDEGDVKKDQGKKQEEERERAAGRFKEHTRDPLAEEQGEDGTTDLAAASRARRATRMLFDTGRDLNSFDRSYFQSAHIGDIHLRMDARHSGAGMRSGPVPDEELRRLRRVHVEPQGYVQLRNALGARRLLVLGAAPGTGRTSTALSLLDEVTGPAADATGTEPGAGSRVRRVDPDGGVRKLAGSLAVEGEEARRGTGYLLELSLTGPGALPPDEMDLDGLAAALARCESYAVVVVTVGSAANPLLAGRYGRLCPPAPTQELLTTRLRERLEEHVAAAPDGEVRLEDLLAGAEELAVRRDVKDAVGLKDLRPAEAELLASLLAAHQLGEVPRDELLAGCRSLAADQAQEWFAGVDRALTAPPAEPEGGAGRPGTAALFHPVAFRIALAVLGGASHSAVAAAAHLLTWELSVQCDPDHTPARPLFCDDPEADLALSRAELTDGRLEVAGTEVPARLIWYRGSALPSAVLTEIWDRHFPVRAPIVRWLRLLADDPRPQVWMRAAVAAGELCARDFDHGYAELIRPLAEAATPRRRIFAATTLDQAAGHASHRKAVRKLVDDWSRYGTKALRWTAAMALGYGNAADTTEDALDALARIGVRDDGEQLAVASFNAVRLLALPDGAKVLRRMADWTHHKRAEYQDLGLVTTVRLAVTSVDEVLSDEPDSPLADRADWPLPLALAVSRPELVLPMADLMWSALNTARSKDVALDALESLLRSAVRGDGTEGTRPGLAALLPALATEENDRRRLDWLLRRMMNDPEDPLPDAQARTLWWLAVPPKERTGEEDSHG
>NZ_CP041607.1|WP_143603281.1|8570774_8571647_+|hypothetical-protein
MDHDAMDLAEARYELVISVDARRSGEYDDVDKQRMRERIYRVLEAAFSHAKVARDAVHMEDRGDGVLLSVAGRIAVTRLLGLWMVEVHENLRDENRGLSVPLGLRVGMHVGPVRHDGRGISGRAVDLACRLADSPLARRLLDAERADLVLVTSQSLYEDVVSSGGKFIEPAHYSSARLELKEGEVTAWFHLPGRPAPEIPTAAPAAPDADRADDVDGVDDARDVRDVSDTCGVDDAPDVDDVRRVDGEDRADAPRAHYTVHGDMSQHSDNVYQQPVHIGRITGDAGRRKG
>NZ_CP041607.1|WP_143605688.1|8569946_8570660_+|cyclic-nucleotide-binding-domain-containing-protein
MGLLGNELAFARALTPQERESVMALGSRKHYAADAHLLTEGDRSSHVLIIIRGWVTVSVATDRGATRLILGLRGPGELLGEMAALDPHPRSATVRALGPTETQVISGDAFRRFLALHPRVSGLVIRQLTFRLRSADQERSALASLTVLQRLAGRLTELSRAEPSGPYNPAVPGGAMHTGTVVQLAQDELAATIGATREAVAKALKLLRTQHVVRTGNRMVEILDPELLALLADGHQE
>NZ_CP041607.1|WP_143603280.1|8568024_8569536_+|cellulose-binding-protein
MPDLPTPQNAAEAALLSECWDAVLSYADLCTSGSASATQLATEAFTHGIDELRAATAASKSTGTGRRALRLPRIPLLLASVRTVAAAWETSGLGHRLDPDLRLWLHSNKAARYVGPPLHRPLALRGLRDMQEPDAVLLWLAEVESLPMSAVARRLGLDPAAASSELAQVRALFRDRCHRNHLDTPMDAHCRSYARLLDAVTRSPSAETPEDLSRHMARCVECAEAAACLRLHGGGLPAALSSGVIGWGGLAYLERRRRAAEAGMIGGRTDAAVDTGLNEGKPVRPRIGRTGILVTAVLVSALALTVSLMPFGGSKGDDANAAQGESTDGQSVADPGPTFPSGSKTKSGSGSGTGTAGSPAVADSTSRPAGNSDQEAQGESSSPAGKQGGAKGSTKSAAPDCRVKYEIVSEWPDGFQATVTVTSTKALATWSLGWTFKDGQRVGQMWDGTFTQDDSHVTATAADYNKTVAANGTFTFGFLGSWTGSNSAARNFTLNKASCQAVG
>NZ_CP041607.1|WP_060901056.1|8566400_8567747_+|hypothetical-protein
MVGSRTALVEDLMERFPHVPREAVFKEDLLRGGVAFDESALSDNEDGDVKPKSYFIFSFDHGTLPELGEAALRRPPEEIILTGGPYDLRRTVVSVRVNPASPYRVAADDEGMLGLYLDGKRIADVGVPPMPEYYRHTLSNGKSVMEVAPTIQWGYLIYLTVFRVCQYFGAKEECQYCDINHNWRQHKAAGRPYTGVKDVEEVLEALEIIDRYDTAKASTAYTLTGGAITSKLQGRDEADFYGHYAKAIEERFPGRWIGKVVAQALPRDDVQRFKDYGVQIYHPNYEVWDRRLFELYCPGKERYVGRDEWHKRILDSAEVFGARNVIPNFVAGVEMAEPFGFTTVDEAIASTTEGLRFFMSHGITPRFTTWCPEPTTPLGKANPQGAPLEYHIRLLEAYRSTMEDFGLSSPPGYGPPGPGHAVFSVSSFMDSLPAREPAVAEAAGPKVP
>NZ_CP041607.1|WP_097286721.1|8564311_8565319_+|hydroxyacid-dehydrogenase
MPERPVAMFAMSAENVPQIFPAEVMTRLREVVDIDPALVAEDFSEPRVREALGGTEILITGWGCPRLDAATLDAAPKLRAVLHSAGSVKGFTTPAVWDRGLVVSSAAVANALPVAEYTLAMILLAGKDLFAQRDRLRARRSVPGWALVPGIGNYGRRVGVVGASRIGRRVIELLRPFDLRVSLTDPYVDEGGAAELGVPLLPLDDLLATSDIVTVHAPQTPETRHLIGRRELGLMPAGSVLINTARGSLVDHDALIDALRVGRLSAILDVTDPEPLPADSPLYDLPNAFVTPHLAGSQGNELTRLGLTVLSEAERVVAGEGVEFGVDVGVLERGA
>NZ_CP041607.1|WP_143603285.1|8586601_8588728_+|hypothetical-protein
MSDFQDRVSDFRDRRSPAAHGEQAGAQGPGGGGTGGSVHQVVFRWDGNQGRQGTGMKAVAHSCPAERAEELGRELGPLLWVSGTAAARQSVVRTLSRDGDVMLVQRWPTTDRGGRPSTISHVLIGDPGTLKIRQCLGLSYGGWGGRESAEKASGRLRVIECAQLDAMARKRLPAMLELLPAVKHALILVAAEWLRDPAQRVSLLAEEKGQPGWPEQDTVPVAYLGLFLLFGRWLGQEWTFATHDTVDTHQLRLTCVPHWEPDAGGAGPLARVTGRRVTPRFEHKAAARLVDHLLDRLRAHPDAPAGVPQLVDELAGGAGLEWARRRVLLHEILSTDRRSGTRADAPAPRSAEPGPVGEGDEGGGDRERAETTTPPRLPKPYAYPAPHLEPRPDVYADPRPDVYADPHPDVYSDPHPDSYADPYPDTYAAPAPEDPPPMAPPRPLRAPVQAPGRTPAHEAYGLHQDLLDHRRGNHMQRGLLAARLRTLPDELLLGELRSADLPPESVELLLDELGNEHRLQERRPEMRHDLCAEVLHNGLYFTQYGQSPEPVSRTAMVTRAADLFTWAVAPLAREERYLRDLRELLHRMTRDSHPTGGNWLRQSIIAPANGQVPDLPPVLWQQILRDVLSRGERAPSAQPSPAAPQPPSASQAPYTVPDPTTAPEPSSTPPRPPTLTSRLSDLTNNPGCVMGVGFSVIAVLITIVLIVL
>NZ_CP041607.1|WP_143603286.1|8589083_8590127_+|hypothetical-protein
MWRPGLRQASFSLGRGAVRLRDPLSERPPHETERSATSRRASNTRAEQAPTRLCWRPAWTNDGASPMGREVVVTLTDCHEYRYPGSVAEPIPVELIDAVRSEDAVLFCGAGLSASQGLPTASSLAQSIAARMRDFDGNPRDLTQVATAYAALRGRHALISFVVESLTQQPWQPGPAHADFAGLPFHAYVTTNWDALVEGALQAANRRHQIVVTDSDVPFLTRSAVPVVKAHGELARPDTLVITDRDYFDLFSLRPSLTHLLDHYFSSKTLVFVGFALADPDFKRLFHACTQRFGPLRRHAYAIQLRPTSADRRIWQAEQVDVIDADARDFAADLVRAMTQPQPSSTA
>NZ_CP041607.1|WP_143603287.1|8590182_8590953_+|hypothetical-protein
MRNALRRIGRDLIERRNIDAYVVSAAALAFAVFDLFSGAVSDEMRWAVLLAGMSLLIFRVTLPAQRVDGSDFLYDRQHLAEVPLSERIERARTLWVLAPSAVNLLSPDTISALRTGMLSRRGSVVRILVLDPDQEHAVQIAEQQLDSSLRFPIQSLRPSIRATLDKLRLMSGWHVTGSLEWRLLDLSPGFSLVAIDPGERQGVLILEIHGYHGDSVSSRMHLELRREDDPRWHNYWADQFEALWNASARPTGTPLP
>NZ_CP041607.1|WP_143603288.1|8590920_8592342_-|radical-SAM-protein
MWERSRISDLLPGISPESHSFTYTYPPPYVAWDRSSCGGFDIAETDAWQDFSMYVHFPFCRMNCNFCSLHRQTAHNESMVSGYLQSLRRELRLLGESRCVPPLQALYLGGGTPTMLSADELNELLDCIAAAAQIPSGADVEVTIECAPEAGRDAQGWYTLFRSLTSRRVLPVTRVSVGVEAWSDVVLARMGRTAATVSAVRALLGAIDESVATYNIDFLVGYPRGPEGPREEARDIVAAVRSLRDQKLRVPSVSIYQLWAVENIPISRASLHTLPPADDLLIELWTVQSALYDFGYMPGYGTAFVRGAEDLHRWTRHRYEAFRHLGFGSGSYSFLPDGLVQRERDLAGYRALLAQQSLDWGEVDRVLNLVTRLSAVDREMRRIICGLRSGTPVLPPPTTASDRELQELGSKLSRLEALEVLERRGEGLTLSADSLLLTNAVSSYLHPVTMPRKPPVARHAALVSRQRGARRSG
>NZ_CP041607.1|WP_143603289.1|8592412_8593426_-|hypothetical-protein
MQEAAQKSAVTVVNSRIEQLAKSLGSLPLAADFAAQMTPVVPVSDEEAFRAYLWTAAVCHATKGGLTGTFGRNRFKGWDFLLRAFSAQAAADADVLSPQNMTDFTADGLHRILTSHSTNTQVNLTDLERRAAILRTTAEELLQKFDGRVMTLLGRADQRAGGQDGAYALLEQLSAFQDPLQKKSSAFLMTVHFSKRWTIQDQESIQPMIDYHRMRVLLRTGCIEIDNPQTAERLRAQLPVEPELEREIRQTSLDVCSRLPRLADMPMFDFDVLLWAHARSCCRHEPMCVSRKAENDSFGSYLDIVDTKRCVFEEWCPGSAKAETRAYWEPIVATENY
>NZ_CP041607.1|WP_143603290.1|8593455_8596500_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MVNVPRELLEAAAIGDVVPVLGDALNPGPPAGAASCDQLALLLAAKLSLPAGSIRPTKDLPSLVSQYEALRGRHALIEVLRQQMGAPDPALPPELLLAVRLAPQALITTSVSLNAEAALRRIGNSTSTVIIDPVATWYTSQDRQPWLIKLAGCVSQPESVALSSDRLMRLSTSIDQLELMVRGILLTKTLVFLAYSLDDPYLEALHTLLQMSSTHSRRRYILTEGVADEEKAVARVWETRGYEVIPGPLRATLEQLVEAGDPSGHSIAAVAPKSSFSSHPFKFLDYYTEQEAAIYFGRDDDAETLATMIATNPLTVIVGPSGVGKTSLINAGLIPRLHTKGYDTCTIRALDHPTKEILKALRSKENGEGSVSDDLQTALSSHSRKRPLVVTIDQFEEFFLRVGPGARRDFAEQLHACLSNDTLDIRLAFVIRDDFLHHMLELSPPLDRILHSHFLVRRLSRSQVSDVLTKTLQEFGIEIEPGLVTRLTDDLDDEGIDPCQLQIIGHTLQRELPPRSRLVKTELYESLGGTSAILARYLDHTLDVLATELLPVAKGVLQCMVSADRTKSVMSTKEIARDVITRRLNVSDDTLQRILHDLTQARVIRSVQGRSEEVFELAHDVLAAKVWGWIEPRDIELKYVRQLLQQSTVDWQQVEILPSHPQWDLVERHRADLEFSPSEALFALHAAYHFASDIAWWTAQAQRCDVDVWAECTQMLDTASLSVRLAVLNWAANSDDSRKFSLLEIALRSEYPAVRRVAHRAMFGDTPLRGGDDEPVFVEVPGGAFLFGTDDVRFEHSQPCHRVTVSTFSIQRYPVTNYEYRQFVRTTGHRAPDHWPGGHLPEQLMEHPVVQVSWWDATKYCTWFAAETGLATRLPTAAEWEKAAGWDPRRGEQSYWSWGDIYDPAKGNSRIGGPGSTTPVGQHTPAGGDSSYGVADMCGNTFDWVSDWWAPGHDPSDTMNPQGPSAGQHKCARGGSWAGSAEGTSVVSNKYSLSPGTRNEYVGFRMAYTVAEDS
>NZ_CP041607.1|WP_143603291.1|8597767_8600485_+|SpoIIE-family-protein-phosphatase
MANRFAGFRRFSLRPLVSRSPRSVAGQVFVLQVALVVLLVACGVFALALQSERDTTAEAKRRSVATAETFAHSPGVVAALRTPDPSKILQPATEAARKAAGVDFIVVMNTKGIRYTHPIPSLIGKRFVGTIGPSLAGRVYTESVHGPLGHEVQATVPIKDGTDKVVGLVSAGLKVKNVTSEVNRQLPIILGAGAGALVVSTGVTALVGRRLRRQTHSLAPDEMTRMYDHHDTVLHSVREGVLIVAGDGRLLLANDEARRLLELPPDAEGQLVSQLSSLEPETVELLVSGREATDEVHFAGERLLAVNQRPTGRDGGIEGTVVTLRDSTELQAVTGRAEVARERLKLLYDAGLGVGTTLDVRRTADELARVAVPRFADFVTVDLADAVLHGEEPATTATDLRRIAVCGIRNDHPLYERGRLIDFVPSTPQARGYGSGRSELVTDLSTATGWHAQDPERTKEIIDYGIHSLIAAPIQAGGVVLGVANFWRAKQHEPFDDEELSLAEELVARAAVSIDNARRYTREHALAVTLQRSLLPRALPEQSALDVGYRYLPAQSGVSGDWFDVIPLPGSRVALAVGDVVGHGLHAAATMGRLRTAVHNFSTLDLPPDELLSHLDDLVGRIDQDEQDTDGVAGVVGATCLYAIYDPVTRRCVMARAGHLAPALVHPDGTVTFVDVPTGPPLGLGGLPFQTAELDIAEGAQLVLYTDGLIEDRRRDLDVGMELLRDALAGHPDRSPEESCQAVLDELLPGRPKDDVALLIARTRGLSSDRIADWDVPLDPAAVAGMRETVSRKLDEWGLSELGFSTELVLSELITNAMRYGSEPIHVRLIHDRTLICEVSDSSSTSPHLRYAATMDEGGRGLFLVSQMAERWGTRYTPQGKVIWAEQTLPRITGQPGPGSRPGTP
>NZ_CP041607.1|WP_054236962.1|8600731_8601841_+|ribosome-small-subunit-dependent-GTPase-A
MTSAFLAFPSSPFAALVPYGWDDVWADEFAPYATEGLLAGRVIRVDRGQCDVVTTDGVLRADTAFVTPNDPMRVVCTGDWVAVEPAGNPRYVRTYLPRRTAFVRSTSSKRSEGQILAANVDYAVVAVSLALELDLGRVERFLALAWESGAQPLVVLTKADLVPDAATLGHLVQDVEKTAPGVPVLPVSSSAGEGLDVLAAVLSGGTSVLLGQSGAGKSTLANALIGEDVMDVRAARDVDGKGRHTTTTRNLLALPGGGVLIDTPGLRGVGLWDAETGVGQVFSEIEGLAADCRFHDCAHEAEPGCAVLAAVDSGVLPERRLASYRKLLRENQRIVAKTDARVRAEIRRDWKRKGAEGRAAMDAKRGRWH
>NZ_CP041607.1|WP_143605689.1|8602316_8603717_+|helix-turn-helix-domain-containing-protein
MERGRRRLVGVIDAETRYEAVRSRDARFDGEFFFAVETTGIYCRPSCPAVTPKRQNVRYYTTAAAAQSSGFRACRRCRPDAVPGSAEWNVRADVVGRAMRLIGDGVVDREGVGGLAVRLGYSARQVQRQLTAEVGAGPVALARAQRAHTARVLLQTTGLPITEIAFAAGFASVRQFNDTIRAVYASTPSELRAAAAPRGGTGTRRTVTPTAGIPLRLAHRGPYQSAAVFDLLAHEAVPGVEDVDGTPGRRTYRRTLRLPYGTGIVAVDERSRGWLDARLHLTDLRDLTTAVQRLRRLFDLDADPYAVDERLGADPRLAPLVAARPGLRSPGAADPDELAVRALVGRTEAERLVRRYGKALDAPSGTLTHVFPEPAVLAEAEPDGPLGALTTALADGTLRLDAGAERDEAQEALLALPGLDGRTAAEIRTRALGDPDVVPPGVDVPDAWRPWRSYAVQHLRAAGELE
>NZ_CP041607.1|WP_143603292.1|8604388_8604757_-|PPOX-class-F420-dependent-oxidoreductase
MTEFSEAERAYLTTQRLGRLATVDAHGQPQANPVGFFPQDDGTILIGGYAMGTTKKWRNLQKNPKVALVVDDIVSHQPWKVRGIDIRGDAELLTGPHDLGPHFSEELIRVHPRRIHSWGLED

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Crispr_ID: NZ_CP041607_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_19

8601928-8602060

Orphan

Consensus_repeat	Method
GCGCAGTTCCCCGCGCCCCTGAGGCGGGGGCTTCGCCCCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_19

>merge|NZ_CP041607|19|8601928-8602060|CRISPRCasFinder
GCGCAGTTCCCCGCGCCCCTGAGGCGGGGGCTTCGCCCCGCATTCCCCGCCCGCCCGAAGTTTTTTGGCTGCGGGCCCGGTGGGGGCTGGGTGCGCAGTTCCTCGCGCCCCTGAGGCGGGGGCTTCGCCCCGC

>NZ_CP041607|19|18|8601928-8602060|CRISPRCasFinder
GCGCAGTTCCCCGCGCCCCTGAGGCGGGGGCTTCGCCCCGC	ATTCCCCGCCCGCCCGAAGTTTTTTGGCTGCGGGCCCGGTGGGGGCTGGGT
GCGCAGTTCCTCGCGCCCCTGAGGCGGGGGCTTCGCCCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143603293.1\|8604953_8606195_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238868
NZ_CP041607.1\|WP_143603285.1\|8586601_8588728_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NZ_CP041607.1\|WP_143603296.1\|8610629_8612558_+\|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl\|CDD\|379325
NZ_CP041607.1\|WP_143603287.1\|8590182_8590953_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603294.1\|8606191_8608504_-\|Tat-pathway-signal-sequence-domain-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603291.1\|8597767_8600485_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|369272
NZ_CP041607.1\|WP_143603288.1\|8590920_8592342_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223708
NZ_CP041607.1\|WP_054236970.1\|8615408_8616461_-\|DUF2637-domain-containing-protein	unknown	unknown	gnl\|CDD\|378511
NZ_CP041607.1\|WP_054236967.1\|8609173_8610154_-\|TrmB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224296
NZ_CP041607.1\|WP_143603290.1\|8593455_8596500_-\|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl\|CDD\|335469
NZ_CP041607.1\|WP_143603295.1\|8608654_8609137_-\|DUF456-family-protein	unknown	unknown	gnl\|CDD\|377293
NZ_CP041607.1\|WP_097289275.1\|8614921_8615344_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|340413
NZ_CP041607.1\|WP_143603286.1\|8589083_8590127_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238697
NZ_CP041607.1\|WP_054236962.1\|8600731_8601841_+\|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl\|CDD\|234988
NZ_CP041607.1\|WP_143605689.1\|8602316_8603717_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225080
NZ_CP041607.1\|WP_143603284.1\|8581789_8584411_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143603292.1\|8604388_8604757_-\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274925
NZ_CP041607.1\|WP_143603297.1\|8612639_8614382_+\|pyruvate-dehydrogenase	unknown	unknown	gnl\|CDD\|180614
NZ_CP041607.1\|WP_143603289.1\|8592412_8593426_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370993
NZ_CP041607.1\|WP_143603283.1\|8578319_8581793_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372732

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143603293.1\|8604953_8606195_+\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238868	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	4.76812e-94
NZ_CP041607.1\|WP_143603285.1\|8586601_8588728_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	2.77647e-06
NZ_CP041607.1\|WP_143603296.1\|8610629_8612558_+\|protein-phosphatase-2C-domain-containing-protein	gnl\|CDD\|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	1.05634e-27
NZ_CP041607.1\|WP_143603295.1\|8608654_8609137_-\|DUF456-family-protein	gnl\|CDD\|377293	pfam04306, DUF456, Protein of unknown function (DUF456). This family is a putative membrane protein that contains glycine zipper motifs.	3.71301e-15
NZ_CP041607.1\|WP_143603291.1\|8597767_8600485_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	5.00278e-56
NZ_CP041607.1\|WP_143603288.1\|8590920_8592342_-\|radical-SAM-protein	gnl\|CDD\|223708	COG0635, HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism].	2.69618e-45
NZ_CP041607.1\|WP_054236970.1\|8615408_8616461_-\|DUF2637-domain-containing-protein	gnl\|CDD\|378511	pfam10935, DUF2637, Protein of unknown function (DUF2637). This family of proteins has no known function.	8.01426e-15
NZ_CP041607.1\|WP_054236967.1\|8609173_8610154_-\|TrmB-family-transcriptional-regulator	gnl\|CDD\|224296	COG1378, COG1378, Predicted transcriptional regulators [Transcription].	1.44995e-08
NZ_CP041607.1\|WP_143603290.1\|8593455_8596500_-\|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.81038e-47
NZ_CP041607.1\|WP_097289275.1\|8614921_8615344_+\|ATP-binding-protein	gnl\|CDD\|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	2.07851e-17
NZ_CP041607.1\|WP_143603286.1\|8589083_8590127_+\|hypothetical-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	1.77768e-30
NZ_CP041607.1\|WP_054236962.1\|8600731_8601841_+\|ribosome-small-subunit-dependent-GTPase-A	gnl\|CDD\|234988	PRK01889, PRK01889, GTPase RsgA; Reviewed.	0
NZ_CP041607.1\|WP_143605689.1\|8602316_8603717_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	1.61892e-57
NZ_CP041607.1\|WP_143603289.1\|8592412_8593426_-\|hypothetical-protein	gnl\|CDD\|370993	pfam10343, Q_salvage, Potential Queuosine, Q, salvage protein family. Q_salvage proteins occur in most Eukarya as well as in a few bacteria possible via horizontal gene-transfer. Queuosine (Q) is a chemical modification found at the wobble position of tRNAs that have GUN anticodons. Most bacteria synthesize queuosine de novo, whereas eukaryotes rely solely on salvaging this essential component from the environment or the gut flora. The exact enzymatic function of the domain has yet to be determined, but structural similarity with DNA glycosidases suggests a ribonucleoside hydrolase role.	6.63381e-06
NZ_CP041607.1\|WP_143603292.1\|8604388_8604757_-\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274925	TIGR04023, Pyridoxamine_5'-phosphate_oxidase, PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. This subfamily within the PPOX family occurs in at least 19 distinct species of F420 producers and is likely to bind F420 rather than FMN. The member OxyR was shown to use F420 to catalyze a C5a-C11a reduction in oxytetracycline biosynthesis. [Unknown function, Enzymes of unknown specificity].	1.32343e-61
NZ_CP041607.1\|WP_143603297.1\|8612639_8614382_+\|pyruvate-dehydrogenase	gnl\|CDD\|180614	PRK06546, PRK06546, pyruvate dehydrogenase; Provisional.	0
NZ_CP041607.1\|WP_143603283.1\|8578319_8581793_+\|hypothetical-protein	gnl\|CDD\|372732	pfam13809, Tubulin_2, Tubulin like. Many of the residues conserved in Tubulin, pfam00091, are also highly conserved in this family.	4.75557e-73

>NZ_CP041607.1|WP_054236962.1|8600731_8601841_+|ribosome-small-subunit-dependent-GTPase-A
MTSAFLAFPSSPFAALVPYGWDDVWADEFAPYATEGLLAGRVIRVDRGQCDVVTTDGVLRADTAFVTPNDPMRVVCTGDWVAVEPAGNPRYVRTYLPRRTAFVRSTSSKRSEGQILAANVDYAVVAVSLALELDLGRVERFLALAWESGAQPLVVLTKADLVPDAATLGHLVQDVEKTAPGVPVLPVSSSAGEGLDVLAAVLSGGTSVLLGQSGAGKSTLANALIGEDVMDVRAARDVDGKGRHTTTTRNLLALPGGGVLIDTPGLRGVGLWDAETGVGQVFSEIEGLAADCRFHDCAHEAEPGCAVLAAVDSGVLPERRLASYRKLLRENQRIVAKTDARVRAEIRRDWKRKGAEGRAAMDAKRGRWH
>NZ_CP041607.1|WP_143603291.1|8597767_8600485_+|SpoIIE-family-protein-phosphatase
MANRFAGFRRFSLRPLVSRSPRSVAGQVFVLQVALVVLLVACGVFALALQSERDTTAEAKRRSVATAETFAHSPGVVAALRTPDPSKILQPATEAARKAAGVDFIVVMNTKGIRYTHPIPSLIGKRFVGTIGPSLAGRVYTESVHGPLGHEVQATVPIKDGTDKVVGLVSAGLKVKNVTSEVNRQLPIILGAGAGALVVSTGVTALVGRRLRRQTHSLAPDEMTRMYDHHDTVLHSVREGVLIVAGDGRLLLANDEARRLLELPPDAEGQLVSQLSSLEPETVELLVSGREATDEVHFAGERLLAVNQRPTGRDGGIEGTVVTLRDSTELQAVTGRAEVARERLKLLYDAGLGVGTTLDVRRTADELARVAVPRFADFVTVDLADAVLHGEEPATTATDLRRIAVCGIRNDHPLYERGRLIDFVPSTPQARGYGSGRSELVTDLSTATGWHAQDPERTKEIIDYGIHSLIAAPIQAGGVVLGVANFWRAKQHEPFDDEELSLAEELVARAAVSIDNARRYTREHALAVTLQRSLLPRALPEQSALDVGYRYLPAQSGVSGDWFDVIPLPGSRVALAVGDVVGHGLHAAATMGRLRTAVHNFSTLDLPPDELLSHLDDLVGRIDQDEQDTDGVAGVVGATCLYAIYDPVTRRCVMARAGHLAPALVHPDGTVTFVDVPTGPPLGLGGLPFQTAELDIAEGAQLVLYTDGLIEDRRRDLDVGMELLRDALAGHPDRSPEESCQAVLDELLPGRPKDDVALLIARTRGLSSDRIADWDVPLDPAAVAGMRETVSRKLDEWGLSELGFSTELVLSELITNAMRYGSEPIHVRLIHDRTLICEVSDSSSTSPHLRYAATMDEGGRGLFLVSQMAERWGTRYTPQGKVIWAEQTLPRITGQPGPGSRPGTP
>NZ_CP041607.1|WP_143603290.1|8593455_8596500_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MVNVPRELLEAAAIGDVVPVLGDALNPGPPAGAASCDQLALLLAAKLSLPAGSIRPTKDLPSLVSQYEALRGRHALIEVLRQQMGAPDPALPPELLLAVRLAPQALITTSVSLNAEAALRRIGNSTSTVIIDPVATWYTSQDRQPWLIKLAGCVSQPESVALSSDRLMRLSTSIDQLELMVRGILLTKTLVFLAYSLDDPYLEALHTLLQMSSTHSRRRYILTEGVADEEKAVARVWETRGYEVIPGPLRATLEQLVEAGDPSGHSIAAVAPKSSFSSHPFKFLDYYTEQEAAIYFGRDDDAETLATMIATNPLTVIVGPSGVGKTSLINAGLIPRLHTKGYDTCTIRALDHPTKEILKALRSKENGEGSVSDDLQTALSSHSRKRPLVVTIDQFEEFFLRVGPGARRDFAEQLHACLSNDTLDIRLAFVIRDDFLHHMLELSPPLDRILHSHFLVRRLSRSQVSDVLTKTLQEFGIEIEPGLVTRLTDDLDDEGIDPCQLQIIGHTLQRELPPRSRLVKTELYESLGGTSAILARYLDHTLDVLATELLPVAKGVLQCMVSADRTKSVMSTKEIARDVITRRLNVSDDTLQRILHDLTQARVIRSVQGRSEEVFELAHDVLAAKVWGWIEPRDIELKYVRQLLQQSTVDWQQVEILPSHPQWDLVERHRADLEFSPSEALFALHAAYHFASDIAWWTAQAQRCDVDVWAECTQMLDTASLSVRLAVLNWAANSDDSRKFSLLEIALRSEYPAVRRVAHRAMFGDTPLRGGDDEPVFVEVPGGAFLFGTDDVRFEHSQPCHRVTVSTFSIQRYPVTNYEYRQFVRTTGHRAPDHWPGGHLPEQLMEHPVVQVSWWDATKYCTWFAAETGLATRLPTAAEWEKAAGWDPRRGEQSYWSWGDIYDPAKGNSRIGGPGSTTPVGQHTPAGGDSSYGVADMCGNTFDWVSDWWAPGHDPSDTMNPQGPSAGQHKCARGGSWAGSAEGTSVVSNKYSLSPGTRNEYVGFRMAYTVAEDS
>NZ_CP041607.1|WP_143603289.1|8592412_8593426_-|hypothetical-protein
MQEAAQKSAVTVVNSRIEQLAKSLGSLPLAADFAAQMTPVVPVSDEEAFRAYLWTAAVCHATKGGLTGTFGRNRFKGWDFLLRAFSAQAAADADVLSPQNMTDFTADGLHRILTSHSTNTQVNLTDLERRAAILRTTAEELLQKFDGRVMTLLGRADQRAGGQDGAYALLEQLSAFQDPLQKKSSAFLMTVHFSKRWTIQDQESIQPMIDYHRMRVLLRTGCIEIDNPQTAERLRAQLPVEPELEREIRQTSLDVCSRLPRLADMPMFDFDVLLWAHARSCCRHEPMCVSRKAENDSFGSYLDIVDTKRCVFEEWCPGSAKAETRAYWEPIVATENY
>NZ_CP041607.1|WP_143603288.1|8590920_8592342_-|radical-SAM-protein
MWERSRISDLLPGISPESHSFTYTYPPPYVAWDRSSCGGFDIAETDAWQDFSMYVHFPFCRMNCNFCSLHRQTAHNESMVSGYLQSLRRELRLLGESRCVPPLQALYLGGGTPTMLSADELNELLDCIAAAAQIPSGADVEVTIECAPEAGRDAQGWYTLFRSLTSRRVLPVTRVSVGVEAWSDVVLARMGRTAATVSAVRALLGAIDESVATYNIDFLVGYPRGPEGPREEARDIVAAVRSLRDQKLRVPSVSIYQLWAVENIPISRASLHTLPPADDLLIELWTVQSALYDFGYMPGYGTAFVRGAEDLHRWTRHRYEAFRHLGFGSGSYSFLPDGLVQRERDLAGYRALLAQQSLDWGEVDRVLNLVTRLSAVDREMRRIICGLRSGTPVLPPPTTASDRELQELGSKLSRLEALEVLERRGEGLTLSADSLLLTNAVSSYLHPVTMPRKPPVARHAALVSRQRGARRSG
>NZ_CP041607.1|WP_143603287.1|8590182_8590953_+|hypothetical-protein
MRNALRRIGRDLIERRNIDAYVVSAAALAFAVFDLFSGAVSDEMRWAVLLAGMSLLIFRVTLPAQRVDGSDFLYDRQHLAEVPLSERIERARTLWVLAPSAVNLLSPDTISALRTGMLSRRGSVVRILVLDPDQEHAVQIAEQQLDSSLRFPIQSLRPSIRATLDKLRLMSGWHVTGSLEWRLLDLSPGFSLVAIDPGERQGVLILEIHGYHGDSVSSRMHLELRREDDPRWHNYWADQFEALWNASARPTGTPLP
>NZ_CP041607.1|WP_143603286.1|8589083_8590127_+|hypothetical-protein
MWRPGLRQASFSLGRGAVRLRDPLSERPPHETERSATSRRASNTRAEQAPTRLCWRPAWTNDGASPMGREVVVTLTDCHEYRYPGSVAEPIPVELIDAVRSEDAVLFCGAGLSASQGLPTASSLAQSIAARMRDFDGNPRDLTQVATAYAALRGRHALISFVVESLTQQPWQPGPAHADFAGLPFHAYVTTNWDALVEGALQAANRRHQIVVTDSDVPFLTRSAVPVVKAHGELARPDTLVITDRDYFDLFSLRPSLTHLLDHYFSSKTLVFVGFALADPDFKRLFHACTQRFGPLRRHAYAIQLRPTSADRRIWQAEQVDVIDADARDFAADLVRAMTQPQPSSTA
>NZ_CP041607.1|WP_143603285.1|8586601_8588728_+|hypothetical-protein
MSDFQDRVSDFRDRRSPAAHGEQAGAQGPGGGGTGGSVHQVVFRWDGNQGRQGTGMKAVAHSCPAERAEELGRELGPLLWVSGTAAARQSVVRTLSRDGDVMLVQRWPTTDRGGRPSTISHVLIGDPGTLKIRQCLGLSYGGWGGRESAEKASGRLRVIECAQLDAMARKRLPAMLELLPAVKHALILVAAEWLRDPAQRVSLLAEEKGQPGWPEQDTVPVAYLGLFLLFGRWLGQEWTFATHDTVDTHQLRLTCVPHWEPDAGGAGPLARVTGRRVTPRFEHKAAARLVDHLLDRLRAHPDAPAGVPQLVDELAGGAGLEWARRRVLLHEILSTDRRSGTRADAPAPRSAEPGPVGEGDEGGGDRERAETTTPPRLPKPYAYPAPHLEPRPDVYADPRPDVYADPHPDVYSDPHPDSYADPYPDTYAAPAPEDPPPMAPPRPLRAPVQAPGRTPAHEAYGLHQDLLDHRRGNHMQRGLLAARLRTLPDELLLGELRSADLPPESVELLLDELGNEHRLQERRPEMRHDLCAEVLHNGLYFTQYGQSPEPVSRTAMVTRAADLFTWAVAPLAREERYLRDLRELLHRMTRDSHPTGGNWLRQSIIAPANGQVPDLPPVLWQQILRDVLSRGERAPSAQPSPAAPQPPSASQAPYTVPDPTTAPEPSSTPPRPPTLTSRLSDLTNNPGCVMGVGFSVIAVLITIVLIVL
>NZ_CP041607.1|WP_143603284.1|8581789_8584411_+|hypothetical-protein
MKTSEDLGTVIRLDLRSGAAELDTAKTLRASVARQLGRAGLPEPDDPLFLVIDTPAGLTDHQRQYELLTAYRAVGEVRILVLLVGSAPGSYAGEDEAFQPDRRLVRPAVLRASGTALLWAGDLRSARTALEQPEPDAPEALAVLVDVLSVPDVYLKVLDGLGALPDAVAAPGVRLLEQDLPLEVRDRAWRDALVRFAGEDTELAPDLLATASTGADLPEPLRSLVAGRGGRDQRHREPGGVADSTYAACAQALDYAEDALAGLRSLPGLLWASRRQAFEADLDQAHQALGEYRDLVGTALRGGGSGTAPSAAETAARLGALGLRVPSAEGMGERIGEGLREFAGKLLGQGLALRSVAQRFTGLAGRVEPVPGSALVRKLADHSTEALSRQPVVGNGPVATGHGALPAAAVAGLLGGLWRGPLAALAIAVPLVFLAVALLGASRLRGAGRPGRWGWGPRAAALGGAAAGVAVAYAVEPPLWLSALGLLAGLGLAVETARRLWRAAIDSWAAFHATTALREALAGLDALLAEAVREHWAVEERLHCADAARSVAGMLRATAAAAAAEAVPEPERPTVTGAPGPEPLDADDWLTSTSVLETDAFAVPDDGDSDWASAYAWQDGASWSEPGEPGQPGARGGFAESAGPADPWADRTAGVPRWLDRESGEGGPELVAVLAGDLTDAAMVAMEPYWGAVERGQAGALAVRRTEERVRDLLSTARRHLQHNGVLAPPPFAADHRTRAGSANLLGTDPRRVADLVGTEADRQAVVQLSSPEQGTLLSRDPAAAVWIRFAPEAVRDEVEKTWRTTGCVPPEQTLWTSSGRYAGLVRLTPLRMGVVDTVRSRQNSPADGFDPYDREDAYDRADAHDREDGDSW
>NZ_CP041607.1|WP_143603283.1|8578319_8581793_+|hypothetical-protein
MKIFQPMLFVGLGGTGGLVGAELERKLRAELCGPDGVALSHLSGHAPYQLPDCLQFVYADYSESDLQRLPQFNVDPSLRAAYSRTSRATHNLLPNFDASPELTKMLRASLRDEVADWLPPRIDEPKVTPLHNGAGQLPTVGRAALFATLRHSLAPVLEPLLQAIDAIAKSAGELAELGGGKVNGCDVFVAFSVAGGTGAGIFLDYLHLINHAFQLRRFDGVKIYPLVVMPSSFSSAGGGGREAELNAARALVDLFRLVDAQNAPSEGTEIGDLDLDLDSGLGIRYPGTTPIRLRTGILPTAFLFSPTAGIRQDDLRRSIVSLVMSLIGTELGDSRPRGRATATDDDFQTFAASFINRGVHRSAVSPTGIGRQGVSTSLVASMTAPMDQLADLVAGRLLREAVTDLVERPRTALRDNAVPLIRQLFADSHLEELWERAQLAVPEPDPLPRGGKAIEQALGERLTDMQRLLSDLQSIADRQAASMADRFAPRPAIDKLLQSVDPFLAERIVRGVQDSDEPIARLGFLGMLDSRSRAPQRPPGVTDQPPKTPRIKGRLAGMSPARWGDDDVQAALQEQDLWYQWRSRTVWHEAWREQQQQWQPPAATAGADLGRLVNAFRKHSDQERKVSAQKGLELYEDRTGISYLLPPQRTLNHFYEDVVTRLIRREGMRENDDEAALLLRMIDGDTWREVHTLSRRNPDNAVAVVKAQLEGRITRLFAESGEHLEERPLLPAMGTLLAAAAGDADAADQVSKEALDLFGRKLTGLLPVGFTPEGTGPLRVLVTHPRVQAVEEVQEYLGKALRLPSDAKNSVEYRGVESDSVTVVLFRSEMSLTQVPEARKVLRQWARAKDSEQAQDVLRWRQRLGYRDSWMVSSEEDRRVILHRLLCCMWNGQVDVVDGDPASPERLRLRLFPEKGAHVPGVRLRLGDFPGGVSSWAELLRSYERWTVLDDERTVEDYCRELMGAQPLGLARSASEPHPLFVELVEKTAPRQLELLADRRERGGERVEGWVRPLWEFWAKTLPAALDTEFGDQRAVQPTLRTLLEHVRGGTPAQRVRKEVPEPRRAVADEDDWGTAPRASFDKYPSGAEERPRRASVDDYDDGYDADRGDRGDRVNGRSGGADRPSVPWDEPGDPGPYGDDGERERSRRNPWDGDPE
>NZ_CP041607.1|WP_143605689.1|8602316_8603717_+|helix-turn-helix-domain-containing-protein
MERGRRRLVGVIDAETRYEAVRSRDARFDGEFFFAVETTGIYCRPSCPAVTPKRQNVRYYTTAAAAQSSGFRACRRCRPDAVPGSAEWNVRADVVGRAMRLIGDGVVDREGVGGLAVRLGYSARQVQRQLTAEVGAGPVALARAQRAHTARVLLQTTGLPITEIAFAAGFASVRQFNDTIRAVYASTPSELRAAAAPRGGTGTRRTVTPTAGIPLRLAHRGPYQSAAVFDLLAHEAVPGVEDVDGTPGRRTYRRTLRLPYGTGIVAVDERSRGWLDARLHLTDLRDLTTAVQRLRRLFDLDADPYAVDERLGADPRLAPLVAARPGLRSPGAADPDELAVRALVGRTEAERLVRRYGKALDAPSGTLTHVFPEPAVLAEAEPDGPLGALTTALADGTLRLDAGAERDEAQEALLALPGLDGRTAAEIRTRALGDPDVVPPGVDVPDAWRPWRSYAVQHLRAAGELE
>NZ_CP041607.1|WP_143603292.1|8604388_8604757_-|PPOX-class-F420-dependent-oxidoreductase
MTEFSEAERAYLTTQRLGRLATVDAHGQPQANPVGFFPQDDGTILIGGYAMGTTKKWRNLQKNPKVALVVDDIVSHQPWKVRGIDIRGDAELLTGPHDLGPHFSEELIRVHPRRIHSWGLED
>NZ_CP041607.1|WP_143603293.1|8604953_8606195_+|SGNH/GDSL-hydrolase-family-protein
MTRVIKARHLFTALVTVLALVPPTASANAGSTSLTAHDDDQARWTGTWETAPSGTAPALPGASIRNVVHTSVGGSAARVRVSNRLGNAPLQLDAVTVALQEWGRPMSPNAAPGSLRVATFAGRRSVTVPVGQDMVSDPVDLPVPADANLLVSVHTPADSGPATYHRSAFQANFLAREGDRTADEPGTAYTVTLDNWYYVTGVDVLDAPAAGSVVALGDSLTDGTGSTYSANRRWPDLLAARLRTLPAYRRLGVLNAGISGNRLLLENGGPSALTRLDADALSRAGVRAVIVLEGINDIKGTPEQTDPLAIEDAYRRIVERAHARGIRVVGATITPYGGYSAYTERREAIRLTVNAFIRNADLFDAVVDFDAAVRDPADPHRILPAYDPGDHLHFNDTGMRALADDIDLDTLLL
>NZ_CP041607.1|WP_143603294.1|8606191_8608504_-|Tat-pathway-signal-sequence-domain-protein
MPSPSRRTVLATGSALGGTLLAGGLPAQARAADHPDTSDPWHTVLDDADLVWQRMPKTWYEGPYLGNGFLGSGIYAEPGAETGSFSAVRFNVQHSQVQDHRPEFGSLFGLARLPIGWFTLEPVGAITGLDWRLGLRDAELTGTLTTDKGTLTLRALVHNSRSVLAVEVTPSEGERDFRWVFHPADAISPRADFKPLPDGYQGNPPAEVATHDGVSTAVQPLLSGGQHVTAWRERTRGRTRCLYVHVAHSYPKSTALGRALATVRAASALSYDLLAETHRAWWHAYYRKSFLSLPDARIQRFYWIQLYKTASAARRDAPVMATSGPWLESTPWPNTWWNLNVQLEYWLIHGSNHLELDAVTRALSEFRDNLSKEVSDRYRADSLGIPRTTDPQLVNGAAGTLTGYGVGIPGQDPPTPEVGNLTWALHNVWLSYRHTMDESILRDVLFPLLRKAVNYYLHFLEPGTDGKLHLPATFSPEYGGNSRDCNYDLMLLTWGCRTLLESAELLGLDDELAPRWREVLAKRVAYPTDANGFVIGADIPFAKSHRHYSHLLAVYPLYELTGRTPDERALIEKSLAHWVGFEGALQGYTFTGAASMSALLGKGEDALKYLGQLMTRFIQPNTMYKESGPVIETPLSAAQSLHDMVCQSWGGVVRVFPALPAEWADLTVHDFRTQGAFLLSAVRKGGVTRWVRLVSEAGAPCVVRHGIAGAIDVRDGRGRQLRYETVGDGTIHVTLRRGESALITAKGDRPDLTVTPVRPNADAPRWGLPA
>NZ_CP041607.1|WP_143603295.1|8608654_8609137_-|DUF456-family-protein
MGAWELLLVGVVIVLGLCGVLVPGVPGSWLVWAAVLWWALTDPRALTWGVLVGASVVLVLAQAIRWGLPPRRLREAGATPRMGVYAGVGTLLGFILLPVVGAVAGFLGGIYLYERPRLGGHGPAKAAVGTVMRSGGWHVLTELFACLLVTAAWLATVIWG
>NZ_CP041607.1|WP_054236967.1|8609173_8610154_-|TrmB-family-transcriptional-regulator
MLGAIGLDETHESAYRALVSVGAADVPDLARRLTLGEHDTERALRRLERHGLAAQSSGRPGRWVAAPPGVALGALLTQQRHELEKAELAAALLAEEYRAQATEPAVHDLVEVVIGAAAVTQRFLQLQLGAATEVCALVTGNPMVVSGMDNDAEEQAAGRGVGYRVVLERAVLDQPTGLTELSAALSRDEQVRVVDKVPTKLVIADRSLAMVPLTSHTAEPAALVVHASGLLELLSGLFESVWRDALPLRLGSRGVMEQEPDGPDVTDLEILSLLLAGLTDASVAKQLDLGLRTVQRRVKRLMELAGVTTRLQLGWHAYEKGWVARD
>NZ_CP041607.1|WP_143603296.1|8610629_8612558_+|protein-phosphatase-2C-domain-containing-protein
MSQQGERPTGHEDDWWGQLYDATGDTGPTPAADSLDDRFASAAGTVGSGSEPPEPEGPPVVPEQRGGGATPRGEAPGRRPARWDREPPSDPPDRFLDPTGPAEDLPPSTSADAALDPSEIEDAVPSGSGEGVGRPGSGEGLGPSGSGEDPGPLWSGGGRGSSRSGGDLGLPGDGPGDGEGSGFSRGGGDPGLSWSSGYPGPSGSGEDPGLSSADAEPGPWWSREATGFSRGGADPRSSGGGEEPLPPWGPPPAEPPTPATFPPGPTPPGFHAESLRGRTPKEPPGAAVPPRPTAPPHPAPPGAAASEDALPEPVLTVPHQPPPVDHVGSGPPTYDAEPTALPPADPDDLDDLVADTVLDGARYGASTLRAASVRGDSARFRGEPRRDSLLTARFGAGEHALVLVAMATGARATPGAHRAAAEACRWIGRAVGRSHARLAEDIRAARRGDLKSGLHRLTDRSLGKLRASAAEQGIEPEEYTAGLRCLLFTGDPECRTRVFFGVGDGGLFRLRDGEWQDIEPRVAETTGEAVVGFGSLPHETPEGDRLTMDLGITTPPSPYEPAPEPPREPFRFRASVARPGDTLLLCTGGLAEPLRGEPQLCEHLTERWSAAEPPGLAAFLADTQVRVKGYADDRTVAAVWEA
>NZ_CP041607.1|WP_143603297.1|8612639_8614382_+|pyruvate-dehydrogenase
MAKQNVAEQFVDILVRAGVKRLYGVVGDSLNPVVDAIRRNAAIDWIHVRHEETAAFAAGAEAQITGKLAACAGSCGPGNLHLINGLYDAHRSMAPVLALASHIPSSEIGLGYFQETHPDQLFRECSHYNEMISNPKQMPRLLQTAIQHAVGQSGVSVVSLPGDIASEPAPDKALETALVTSRPTVRPGDTEIDKLVAMIDEADRITLFCGSGTAGAHAEVMEFAEKIKSPVGHALRGKEWIQYDNPYDVGMSGLLGYGAAYEATHECDLLILLGTDFPYNAFLPDDVKIAQVDVRPERLGRRSKLDLAVWGDVKETLRCLTPRVKPKGNRRFLDKMLKKHADALEGVVKAYTRKVEKHVPIHPEYVASVLDELADEDAVFTVDTGMCNVWAARYISPNGRRRVIGSFSHGSMANALPMAIGAQFTDRGRQVVSMSGDGGFAMLMGDFLTLVQYDLPVKVVLFNNSALSMVELEMLVAGLPSYGTTTKNPDFGAVARACGAYGVRVEKPKDLTGALKAAFKHKGPALVDVVTDPNALSIPPKISAEMVTGFALSASKMVLDGGVGRMVQMARSNLRNVPRP
>NZ_CP041607.1|WP_097289275.1|8614921_8615344_+|ATP-binding-protein
MEEEATDGTREPAAAQLRRRLARADLRAVPEARRALRELLRHWGKPEKSEIAELLTSELVTNALIHTDHDAVLTATVGPRGLHVEVRDFVGRRPRLRVPIADDGTHGRGLVLVQSLADAWGVRPHGVGKSVWFELDGGAV
>NZ_CP041607.1|WP_054236970.1|8615408_8616461_-|DUF2637-domain-containing-protein
MRLTDISLNWLLPGAVLLLGLLAAVAVLARSKRSGENASSNNDDSWERSEERRRRKEAVYGTASYVLLFCCAAVAAALSFHGLVGFGQQNLGLTDGWEYLVPFGLDGAAMFCSVLAVREASHGDAALGSRILVWTFAGAAAWFNWVHAPRGVDHSGAPQFFAGMSLSAAVLFDRALKQTRRAALREQGLVPRPLPQIRIVRWLRAPRETYSAWSLMLLENVRTLDEAVEEVREDKRQKEQNRLRRRNEERVERAHLKALSRGHRGLPGRGGGGGGGRQQLETTVERAPAQATAEPAIAPELPVRSRPSLQPVRKSGDPITVDLTAEDDTMALPRLDSLERKLKDLEQQFG

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Crispr_ID: NZ_CP041607_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_20

9634437-9634520

Orphan

Consensus_repeat	Method
CCCCGGAGTCCCGTGCCCGTGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_20

>merge|NZ_CP041607|20|9634437-9634520|CRISPRCasFinder
CCCCGGAGTCCCGTGCCCGTGGCCCCCGGGCGCAGGTGCGCCGTGGTGGTGTCCTTCCGCCCCGGCAGTCCCGTGCCCGTGGCC

>NZ_CP041607|20|19|9634437-9634520|CRISPRCasFinder
CCCCGGAGTCCCGTGCCCGTGGCC	CCCGGGCGCAGGTGCGCCGTGGTGGTGTCCTTCCGC
CCCGGCAGTCCCGTGCCCGTGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_097287407.1\|9628274_9629606_+\|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	unknown	unknown	gnl\|CDD\|274360
NZ_CP041607.1\|WP_143603911.1\|9642812_9644345_+\|alpha-L-fucosidase	unknown	unknown	gnl\|CDD\|226195
NZ_CP041607.1\|WP_054234950.1\|9647013_9647910_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP041607.1\|WP_054234963.1\|9623947_9625168_+\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234846
NZ_CP041607.1\|WP_143603903.1\|9625405_9628012_+\|glycoside-hydrolase-family-2	unknown	unknown	gnl\|CDD\|225789
NZ_CP041607.1\|WP_143603908.1\|9638565_9640905_+\|alpha-L-fucosidase	unknown	unknown	gnl\|CDD\|376461
NZ_CP041607.1\|WP_143603901.1\|9619017_9620229_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|366703
NZ_CP041607.1\|WP_054234952.1\|9644448_9645492_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP041607.1\|WP_097289376.1\|9629803_9631255_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|237218
NZ_CP041607.1\|WP_097287416.1\|9645712_9647005_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NZ_CP041607.1\|WP_143603905.1\|9631263_9632880_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP041607.1\|WP_097287412.1\|9636969_9638313_-\|amidase	unknown	unknown	gnl\|CDD\|223232
NZ_CP041607.1\|WP_097287410.1\|9633850_9634306_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|132319
NZ_CP041607.1\|WP_143603906.1\|9633024_9633825_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235975
NZ_CP041607.1\|WP_143603913.1\|9648909_9650169_+\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|225344
NZ_CP041607.1\|WP_143605748.1\|9647963_9648872_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223472
NZ_CP041607.1\|WP_054234957.1\|9636457_9636940_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224168
NZ_CP041607.1\|WP_060900917.1\|9622714_9623866_+\|glycogen-synthase	unknown	unknown	gnl\|CDD\|273997
NZ_CP041607.1\|WP_097289375.1\|9621889_9622633_+\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|378676
NZ_CP041607.1\|WP_143603910.1\|9640897_9642793_+\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119334

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_097287407.1\|9628274_9629606_+\|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	gnl\|CDD\|274360	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT. This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity].	5.41809e-109
NZ_CP041607.1\|WP_143603911.1\|9642812_9644345_+\|alpha-L-fucosidase	gnl\|CDD\|226195	COG3669, COG3669, Alpha-L-fucosidase [Carbohydrate transport and metabolism].	6.27125e-55
NZ_CP041607.1\|WP_054234950.1\|9647013_9647910_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	4.08599e-74
NZ_CP041607.1\|WP_054234963.1\|9623947_9625168_+\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|234846	PRK00844, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NZ_CP041607.1\|WP_143603903.1\|9625405_9628012_+\|glycoside-hydrolase-family-2	gnl\|CDD\|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	8.42481e-37
NZ_CP041607.1\|WP_143603908.1\|9638565_9640905_+\|alpha-L-fucosidase	gnl\|CDD\|376461	pfam01120, Alpha_L_fucos, Alpha-L-fucosidase.	8.66654e-125
NZ_CP041607.1\|WP_143603901.1\|9619017_9620229_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.44819e-40
NZ_CP041607.1\|WP_054234952.1\|9644448_9645492_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.54601e-80
NZ_CP041607.1\|WP_097289376.1\|9629803_9631255_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|237218	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	8.23666e-13
NZ_CP041607.1\|WP_097287416.1\|9645712_9647005_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.03837e-53
NZ_CP041607.1\|WP_143603905.1\|9631263_9632880_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.14533e-49
NZ_CP041607.1\|WP_097287412.1\|9636969_9638313_-\|amidase	gnl\|CDD\|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	2.71287e-104
NZ_CP041607.1\|WP_097287410.1\|9633850_9634306_-\|hypothetical-protein	gnl\|CDD\|132319	TIGR03276, Phn-HD, phosphonate degradation operons associated HDIG domain protein. This small clade of proteins are found adjacent to other genes implicated in the catabolism of phosphonates. They are members of the TIGR00277 domain family and contain a series of five invariant histidines (the domain in general has only four).	6.57395e-06
NZ_CP041607.1\|WP_143603906.1\|9633024_9633825_-\|glucose-1-dehydrogenase	gnl\|CDD\|235975	PRK07231, FabG-like, SDR family oxidoreductase.	1.06956e-99
NZ_CP041607.1\|WP_143603913.1\|9648909_9650169_+\|glycosyl-hydrolase	gnl\|CDD\|225344	COG2730, BglC, Endoglucanase [Carbohydrate transport and metabolism].	0.00288721
NZ_CP041607.1\|WP_143605748.1\|9647963_9648872_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.06157e-87
NZ_CP041607.1\|WP_054234957.1\|9636457_9636940_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	3.20644e-11
NZ_CP041607.1\|WP_060900917.1\|9622714_9623866_+\|glycogen-synthase	gnl\|CDD\|273997	TIGR02149, glgA_Coryne, glycogen synthase, Corynebacterium family. This model describes Corynebacterium glutamicum GlgA and closely related proteins in several other species. This enzyme is required for glycogen biosynthesis and appears to replace the distantly related TIGR02095 family of ADP-glucose type glycogen synthase in Corynebacterium glutamicum, Mycobacterium tuberculosis, Bifidobacterium longum, and Streptomyces coelicolor. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP041607.1\|WP_097289375.1\|9621889_9622633_+\|(2Fe-2S)-binding-protein	gnl\|CDD\|378676	pfam11575, FhuF_C, FhuF 2Fe-2S C-terminal domain. This family consists of several bacterial ferric iron reductase protein (FhuF) sequences. FhuF is involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. This domain is the C-terminal domain that contains 4 conserved cysteine residues that are found to be part of a 2Fe-2S cluster.	2.25322e-08
NZ_CP041607.1\|WP_143603910.1\|9640897_9642793_+\|family-20-glycosylhydrolase	gnl\|CDD\|119334	cd06564, GH20_DspB_LnbB-like, Glycosyl hydrolase family 20 (GH20) catalytic domain of dispersin B (DspB), lacto-N-biosidase (LnbB) and related proteins. Dispersin B is a soluble beta-N-acetylglucosamidase found in bacteria that hydrolyzes the beta-1,6-linkages of PGA (poly-beta-(1,6)-N-acetylglucosamine), a major component of the extracellular polysaccharide matrix. Lacto-N-biosidase hydrolyzes lacto-N-biose (LNB) type I oligosaccharides at the nonreducing terminus to produce lacto-N-biose as part of the GNB/LNB (galacto-N-biose/lacto-N-biose I) degradation pathway. The lacto-N-biosidase from Bifidobacterium bifidum has this GH20 domain, a carbohydrate binding module 32, and a bacterial immunoglobulin-like domain 2, as well as a YSIRK signal peptide and a G5 membrane anchor at the N and C termini, respectively. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	1.12571e-58

>NZ_CP041607.1|WP_097287410.1|9633850_9634306_-|hypothetical-protein
MELRSVEELMDLLHACRGARDTPGRCGGRVDLHDHALQTAALLRRSRPADKELQVAGLVHAVGQLLRPGDTAGHADLAADLVRPLLGQRVSRLVGLHAGGWADEADADDVLSLRHADESGRVPGLDAGVLEDWRTVLELVAAQHSRLGAVD
>NZ_CP041607.1|WP_143603906.1|9633024_9633825_-|glucose-1-dehydrogenase
MTTPYGLEGRSAIVTGASRGIGLAVAEELSRAGARVCVTARDPDAVGRAAERLGGVGLAGSVADPAHLRELTELALREFGRIDVVVNNAATNQPYGPLMDADPDRWREAFTVNVEAPLRLVQCAWRAWMGEHGGAVVNVCTEGAGHVGPNVGAYGTSKAALLHLTQQLAGELAPKVRVNSVSPGLVRTEMARFVWENAEDELGAGLPLGRIGRPEDIARAVVWLASDAAGWITGADLLVDGGTRVRSAHSPADTVHERLRTRAPDA
>NZ_CP041607.1|WP_143603905.1|9631263_9632880_-|serine-hydrolase
MVTMGVRRRAGHHRCAALIAAAATSLLGAGHTPSAVAAAPPPQPPPQLTQAKVDDAVGKLDDIVRDAMKRTGVPGVAVAVVHKGRVVHLKGFGERRVGRSGAVDPDTVFQLASLSKPLASTVVAGVVGGRTLGWDDPVAAHLPGFALKDPWVTTHVTYADLFSHRSGLPDHSGDLLEDLGYDRTYILDHLKYEPLGPFRASYAYTNYGVTAAAQAVANAKDTSWDKLSQDTLYGPAGMKNTSSRFSDYDRAKDKAVTHVKNADGTWQPKYVRDADAQSPAGGASSTARDMATWMRLQLANGKLDGRQIIPAAPLERTHLPEIVAQPPQAPAGRAGFYGLGWNVGYDDQGRLRLSHSGAFELGANTNVTMLPGEQLGITVLTNGAPVGLADSVALNFFDIAQHGKPTTDWLPLVDRVYRQQEQQGRSPTDYARPPRNGAVARAADRYTGTYDNAYYGPLTVTAANGELSMSLGPKHTTFRLTHYDGDTFAFRTVGENATGLSGVTFEVGPGSPGSGGSKASRVTVEAWDHGGLGTFTRR
>NZ_CP041607.1|WP_097289376.1|9629803_9631255_+|SDR-family-NAD(P)-dependent-oxidoreductase
MDGEAVSYGPGIDPERLAVCLSVLDELDKIEVDHPDAIAVRRATAGVYRTVKQRRRQERRAAKTAHDKAVTESTATGSAQRIDDETEGILPSSVTDAGEIAGILQRPRSCYICKKRYVEVDYFYHQLCQDCAAENRARRDARADLTGKRALLTGGRAKIGMYIALRLLRDGAHTTITTRFPNDAIRRFKAMPDSDEWIGRLKIVGIDLRDPAQVVALADSVAAEGPLDILINNAAQTVRRSPGAYSELLAAESGPLPAGELPPAEVIGTFGSGAVAALPVAGGGALTAQDVTDLALVSGSASLERIAAGTAIDAGGLVPDLHDTNSWIQSVEEVTPVELLEVQLCNSTAPFILISRLRAAMAASGADRTYIVNVSAMEGVFNRGYKGAGHPHTNMAKAALNMLTRTSAQEMFEKDRILMTAVDTGWITDERPHPDKMRLADAGFHAPLDLIDGAARVYDPIVRGEQGEDLYGVFMKDYAPGKW
>NZ_CP041607.1|WP_097287407.1|9628274_9629606_+|wax-ester/triacylglycerol-synthase-family-O-acyltransferase
MTPDLLAPLDLAFWNIESAQHPMHLGALGVFSAHSPTAGAHAAELLAVRAAGVPGLRMRIRDVWQPLAFPPHFGSAAREPAPDFEPLDHVRLHAPTADFPAAAGRLMERPLQRGRPPWEAHVLPGEDGTSFAVFFKFHHALADGLRALMLAAALMDPLDLPEPRPRPAEPPRGLLPDVRKLPDLVRGTLSDLGRALDIGSSVARATLGARSSPALTSQPTGTRRIAGVALDLDDVHRVRKSVGGTVNDVLIAVVAGALRNWLDERGDSSAGVAPRALIPVSRRRPRTAHPQGNRLSGYLIRLPVDDPDPLGRLRSVRTAMDANKDAGPNRGAGAVALLADHVPPLGHRLGGPVVGQAARLLFDILVTSVPLPSLGLKLGGCPLTEVYPLAPLARGQALAVAVSTYRGRVHYGLVADAQAVPDLNRLARALTEEVETLIIACGP
>NZ_CP041607.1|WP_143603903.1|9625405_9628012_+|glycoside-hydrolase-family-2
MRFGRLRDRLALLLAAALGAAGLASVPAAADDPVAVHGLKGDYYTQSAPGAFDFHELKATGFDPRLDFDDLEPRLRFATGQDNDVSVRWTGKLVPEKSGATTFSIIGDNGFRLWIDGRPVIDHWVDDWDREQTSEPIDLTAGHAYDFKLEYFEHYGGSNLHLRWTEPGGAKVTIPQSAFLLPDGYDYDGALATTVQPDGRTLRLDFARELSAPPAAVVDHLQAVIGGAKWPLGAAELDPADPRSLLVTLKEPVVGDKTGTARGNADLRYDGTGGLAAAGDGKAIGAFWSSGPNHSTYELRTKWADEVGPDNALPEYPRPQLTRDAWRNLNGRWQFAAATAGEQPPVGKTLGEHILVPYPVESQLSGVERHEDRMWYRRTFTVPADWHIGSGRRLLLNFGAVDWQSEVYVNGVRVAEHRGGYDKFGVDVTDALKPGRSQELIVGVYDPTDAASGENPPLGKQRLDPSGIWYTPTSGIWQTVWMEPVAPDHVDSLELTPDVAGGRLTVEPKGVRDGLPVTATAYEGGRKVATVTGRTGQPLTLKIAHPRLWSPDDPFLYDLRVSVGRDRVGSYFGMRSISVEKVDGTPRTVLNGKPVFMMATLDQGFWPDGLYTAPTDEALAYDLRMHKEMGFNAVRKHIKVEPDRWFYWADRLGLLVWQDMPAMTAGVNPSAAARVEYEREMKLMIDQHISSPSVVMWVTFNEGWGQYDEGRIADQAKAWDPTRLVNGMSGLNLGADGGTGDIMDEHGYPSPALPPAPDGRRALVSGEYGGLGLAVPGHAWSVQQSYVDVDPSTYTDDYLARLAEVRALACRGSNGAVYTQISDVEGELNGLLTYDRKVVKPDVGRLRAAHEALIADASRATPTGCPAT
>NZ_CP041607.1|WP_054234963.1|9623947_9625168_+|glucose-1-phosphate-adenylyltransferase
MRRGGPSVLGIVLAGGEGKRLMPLTADRAKPAVTFGGTYRLVDFVLSNLVNADILRICVLTQYKSHSLDRHVTTTWRMSSLLGNYVTPVPAQQRLGPRWYLGSADAILQSLNLVHDERPDYIAVFGADHVYRMDPRQMLAQHIEGGAGVTVAGIRVPRAESSSFGVISPGSDGQTVEGFLEKPADPPGLPDDPECVFASMGNYIFTTKALVEALQRDAEDVHSVHDMGGSILPMLTDRGEAQLYDFSDNHVPGETTRDQGYWRDVGTLDAYYDAHMDLIAERPAFNLYNRSWPIYTSSGQLSPARFNAGGIASESIVSAGSLIRGQVTRSVLSPGVVVDPGAVVQGSILHDNVHIGRGAVVRGAVLDKNVEVPPGATIGVNPERDADLYTVSKGGVIALGKGRIVP
>NZ_CP041607.1|WP_060900917.1|9622714_9623866_+|glycogen-synthase
MRVGLLTREYPPDVYGGAGVHVEFLARELRTLTDLDVHCWGEGAAGGVVRHRSWSSLDGANDALRTFSVDLAMAAALEGRELVHSHTWYANLAGHFGKLLYGIPHVMTAHSLEPLRPWKAEQLGGGYALSSWAERTAVEAADAVIAVSGAMREDILTCYPALDPAKVRVVHNGIDTALYRPDHGTDVLERIGIDTARPYVLFVGRITRQKGVPHLLRAVRDIDPAVQVVLCAGAPDTPEIDQEFRDLFQELSAVRQGLHWIPQMLPRPDVVQLLTHAAVFVCPSVYEPLGIVNLEAMACGTAVVASRVGGIPEVVEDGVTGVLVPVEENFEAGLALALDSVLADPRAARRMGEAGRERAVREFGWDAVARRTVQLYEEVLKPG
>NZ_CP041607.1|WP_097289375.1|9621889_9622633_+|(2Fe-2S)-binding-protein
MELDPELVALGSLGGFFVLRTGVPPRAPLPTLAQAYASPRDDDPRDVWSDPLNFRVRKVAASLRAPEPRIAVSVAQQGLAARLWSVSLGAVALYGRLPDLDPGLLRWDPDGSAPDDLWLSEVRALPVAAIGEVVRDGHLAPLAAALRTRHRMSEGLLWGNAGSALAGAWRQLHRWAEANGRTDVADRARALAADLFTHPDLSATVDPRTLRRRSCCLYYRLPGGGLCGDCCFDRPPGRTRGGTPGRR
>NZ_CP041607.1|WP_143603901.1|9619017_9620229_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MAVRGRHRRYQPNRINRASLTVTAGGAGMALPLIGTGVAHAADVDTWNKVAACESTDNWSINTGNGYYGGLQFTQSTWEAYGGQVYAPRADQATKDQQIAIAEKVLKGQGPGAWPVCSVRAGLTRGGDTPDVTPAAERTGTRSGTSPQTTKRSVRDVQPQTTPQSRAGTAEMYTVVHGDTLSGIAGSRHVQGGWQRLYEANRSTVGSDPDLILPGQRLNLRGKGQSPAHTESPSSASKKQKTPDKPSTHKTSPHQPSSHKTSSDTAKKTDTLVAPVHAATGTPYRAAGASWSKGYHTGVDFPVPTGTSVKAVAAGQVVSAGWGGSFGYQVVIRHADGRYTQYAHLSAISVKDGQSVVGGQRIGRSGSTGNSTGPHLHFEVRTGPGFGTDVDPVAYLRAGGVRI
>NZ_CP041607.1|WP_054234957.1|9636457_9636940_+|GNAT-family-N-acetyltransferase
MLIREAAADDWPRIWPFWHRIVAAGETYTWDPGTSEEAARALWMAPGKRVYVAEDATGAVVGSAYVTPNYGGPAARVAGAGFMVDPDRAGLGIGRALAEHILAAAKADGYRGMVFNAVVETNPAVKLWTALGFTVLGTVPDAYEHPRHGWVGLHIMYKAL
>NZ_CP041607.1|WP_097287412.1|9636969_9638313_-|amidase
MTSWVGRTATEIAAAVREKRATPHEVVADHLARIDRLDARVGAFRVVRSEAALAEADELAGRADLAELPLAGVPVAVKDNLAVRGEANRNGSAATADIPADHDHPTVARLRAAGAVVVGLTNVPELCVFGTSEGVHGTARNPWDTSRTAGGSSGGSAAAVAAGMVPIALGNDGMGSLRIPAANCGILGLKPGHGTIPAGIGHGDWFGMSENGPLATTVEDARLMFAVLSDTEAIRPSGNLVRKVAVSVRSPLIGVGVGRPYANAAREAGELLAGAGHEVRPADPPYPYWLGTAALMHWTAGTAVDAEDLDPRRLARRTRVHATVGRRFVAGVRTGERREQLRGRLEPFFAEHDVLLTPALARRGPAAAPWHKRGWLRNVLVNTNYSPLTPPWNLTGWPAMAVPFGTLPSGAPAAVQLVGRPGSELELLELASQLEELRPWRRTAPLD
>NZ_CP041607.1|WP_143603908.1|9638565_9640905_+|alpha-L-fucosidase
MSTYPRRQVLGAAAGVAVAATLPLAATAEARPAVEQHGQWVPVPDTIPVPLDAYTDNDGIDTATAPGGSFDGSGYTFPGEELPAGPVEVDGIAFVFPSAAAGARNNVVALGQRIDLPSGRYLSAHFLTAGSYGDASGRATVHYADGSTTTAGLGGADWYATGGSLSAPYRYRPDGTKDEHGVGIGTAEVWIDPQREAVALTLPTINPAEAGKASLHLFALSLQPAAQGRALALRDAHSTFSLLESSGAQSVEATVVNAGTVAVLAGDRVSVGVDVPGARTVEPAHVVRLDPGEQARVRVGIRNRVGTAPGTARPGKVTVTGRGQQVTSAGRELTLGVPDYQPTESSLAGHQAPYWFHRAKFGIFIHWGVYSVPAWSPVGKQYAEWYWNHLQSPDNAVYAYHRDTYGENFAYDDFIPMFTAERFDPRAWVELFRDAGAQYHVLTSKHHEGFALWDTKVSDRNAVKMGPKRDLIRELFDASKKFTPELHRGLYFSMPEWFNPDNPWMGHAPRNPYTLEPLPYTGYTAGKDFVKDYQAPQMLELIHGYDPSLIWCDIGGANDSLHVLAEYFNHGKNRPKPYEVTVNNRSGIGFHDFTTPEYTTYENTVVAKWESSRGLDPFSYGYNKATPDAAYMTAEEVVHSLVDIVSKNGNFLLDIGPRADGTIPDIMQTRLRETGRWLRTNGEAIYDTTYWSRMAQLGEDLRFTVRQNEAFYIHSLTEPGATLTVEAPVPIRGGDKVTMLGHDRPLTWTVSGGSLVVDVPEAARKAGQYVWVFKVEWHG
>NZ_CP041607.1|WP_143603910.1|9640897_9642793_+|family-20-glycosylhydrolase
MADQRAARSVRSRWTRRVVGCVVALLLTLATPAPALARTVRAGTAAVPPVTVPALSNWTPERGSYSIGPGSRIVAPDPAARRVADTLADDLRAAGHGTVPVVRQGAHTGDIVIGVDPSASRLGAEGYELRAGKSLLVTAAAETGAFYGTRTLLQLLAQSDRVPAGSTVDVPQYKERGVGVCACYVHISTAWLENLVRDMAYHKLNQLLLELKVKSDAHPEANAWGYYTKDEIRRLVALGEKYHVEIVPEINSPGHMDPWIQNRPDLQLTDADGVKQPARLDITQDAAFTYYTSLIDEYAQVFTSGSWHMGADEYMLGSDFAKYPQILAYARARYGANATPQDAFIDFVNRVQAYAAAKGKKLRIWNDGLTGANTVPVTAGTTVEHWLNVTTKPSRLIAQGYPLMNAAYSLYLVRGGFHTDTKALYDQSWDPRSFEGEKLASRAGVTGAKISLWPDNGRGETENEVATAMDPALRHIAQVTWGSAHPDPTYAEFTARGAAVGHAPGWRDLTRVPVPEGTYTFRGGAATADLQVRRTADGYVTLRSTTSGGCLEVSGGKLTLNVPLDPGVEVTEAPCVAADTLQRWELAPVRGGGHRLVNAITRMAVHVTDAGRLLQYPPDQEPPTVWQLTTH
>NZ_CP041607.1|WP_143603911.1|9642812_9644345_+|alpha-L-fucosidase
MAISRRLFVLASTALVASTGTSVALAAPGEAPSRIPVSPSDTEDDLVRKASQVRPTARQIAWQNLGRTAFLHFGVNTFTGLEWGTGDEDPDVFQPVGLDTDQWARALRDGGFELAILTVKHHDGFVLHPSRYTDHSVASSSWRGGRGDVLRSFADSMRRHGIKVGVYISPADENQYLHGVYANGSARTERTIPTLVDGDDRTNPRTFTLDATDYGAHMLNQLYEVLTEYGPVDEVWFDGAQGRIPPDKVEKYDWDSWYALVRALAPDASIAVSGPDVRWVGNEGGLAREDEWSVVPVTRKDNGRTDYALAYDAPDEGSRAALVAARPVADYLQWWPAECDVSIRDGWFYHADQQPKSVDELTDIYFRSVGRNSVLLLNIPPDTQGLLPAADVVRLREFRERVDRELPDDLGRGAVVRSSPGVFTVDLGTEHEVDRIRLAEDIRHGQQVESFVVEAYGAGAWSRVAGAGTIGASRILLLSAPVRARRWRLRVTRSRRTARIAEFALHRSRI
>NZ_CP041607.1|WP_054234952.1|9644448_9645492_-|LacI-family-transcriptional-regulator
MPAKRSPARRPTMKDIAQRAGVSESAVSFALNDRPGVSEITRDRVRRVAEQLGWRPSTAARQLSGEGAATVGLVVARPADTLGVDSFFLQLISGIQEVLAERHLGLLFQVVEDVADECAVYRRWWAEHRVDGVMVVDPRTDDPRPDLLEELGLPAVVIGGVPDAGHPGISTVWADDAGAMAAVVDELYALGHRRIVHIAGLPGLAHTERRIRTLRAEAERRGLTEVRSVPTDYSDAEGAAVTRRVLESGTPPTALVYDNDVMAVAGVAAATELGFLVPGDVSVVAWEDSPLCRMVKPWLSALSRDTVQFGRTAAQELTALLDGGPARTVQVPVPRLIERESTGPRGA
>NZ_CP041607.1|WP_097287416.1|9645712_9647005_+|sugar-ABC-transporter-substrate-binding-protein
MRISRRALAAAATVAVLLPLSACGSGSDGSGSTDASGKVEGDITFQTWNLRANFKPYFEGVIADFEKKYPGTHVKWVDQPAEGYADKISADAAGGTLPDVVNVSPDLVAPLVKAGLALDLDKSAAQYKKEYLDGAWASHQIPGMTGTYAFPWYLNTGPLFYNKSLFKEAGLDASKPPTTYDELFADALQLAKKSDGKVATLANVPTIEDFGRYGVELMNKEGTAFAFNDAKGVELLTKYKELYDAKALDPQALTATPESSGKKFLTEAVAMNPGSALDLGNFKKQAPNLYKNIGITDQITSTGKVNMYVMGVMVNSRTKHTPASVAFAHFVTDAQNQMSFAKKVAIFPSTAGSLDDPYFTKEDGTDETRVRIAAAKSLKNAVNYTPVLFSEQMKTALRNEVAKALQGKESPKTALDNAVKACDTLLKQQG
>NZ_CP041607.1|WP_054234950.1|9647013_9647910_+|sugar-ABC-transporter-permease
MASSSSTARVRRQLPTSPWLFAAPGLLVVGVFILYPFVSTVVNAFTDRRTLIPGTFVGLANFRELLHDDMFWIGLRNSTLYVLGVVPALVLLPLLLALLVQKNIPGITFFRSAFYTPVVASIVVVGLIWVWLLDERGLVNSLLESIGVGRVGFLSDQWLLLLSAMAVTVWKGLGYYMIIYLAALANVPRELHEAASVDGAGAVRRFLTVTVPAVRSTMVLVAALSSVAAFKVFSEVYLMAGPDGGPAGEDTTLVMLVQRTGTGLTGRVGYASAISVVVFVVTVALMLLVLRADRKEDA
>NZ_CP041607.1|WP_143605748.1|9647963_9648872_+|ABC-transporter-permease-subunit
MEKERDVERRPPAERGPRRRRITDEHGRRVRGWELALRYLLLLAVLALTVGPFLWQLSTSLKGPTEDIFSSPPKFLPGDPTLHNYKRVADTIPVWDYAFNSLKVAGANVVTNCVGSALAGYALARLRYRGRRVATLVFILAMLVPVEGIIIAQFTTMRELGLNNTLIGVVLPGCIGAMNVLLMRNAFLNLPYEIEEAAFVDGANTWQRFLRIALPSVKGTLAVVAIFAFMGAWDDFLWPLIVLSDPSKFTLTIGLNYLHGTFANDERLVAAGTVIAVAPLIALFACLQRYFFRGVGEGAVKG
>NZ_CP041607.1|WP_143603913.1|9648909_9650169_+|glycosyl-hydrolase
MPSAVRFGVNYTPSEGWFHHWLDFDLDSVRADLDSIAALGLDHIRVFPLWPYFQPNRALIRPRAVEQLLQLVDAAGERGLDVNVDGLQGHLSSFDFLPAWTRTWHRRNLFTDPEVLDGQAVYLRTLAAALADRPHFIGMTLGNEVNQFSAGPPHPDPDRASSAQIDDWLERMLAACEEGAPGRLHLHAEYDATWYQDDMPFTPGQAARRGAVTAVHSWVFNGTAQRHGRTSVPTEHHAAYLIELSKAWADDPHRPVWLQEVGAPAPLIPPEHAAAFTEATVAAALDCPDLWGITWWCSHDVSRDLADFPELEYGLGLLTNDRRPKDSARTLARAAREHHHTPAPRSTALIVPADPAVRSLCAPGGPVFEAFFRLTADGARPTTVLDARADDKEHLAARGITEVVSPDQVLPIPQGETRS

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Crispr_ID: NZ_CP041607_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_21

10101542-10101625

Orphan

Consensus_repeat	Method
CCGCCCGCTGGTACGAGGACCAGGTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041607_21

>merge|NZ_CP041607|21|10101542-10101625|CRISPRCasFinder
CCGCCCGCTGGTACGAGGACCAGGTCGACGCAGCGACCTCGTGGCACGGTGTCAGCACCGCCCGCTGGCACGAGGACCAGGTCG

>NZ_CP041607|21|20|10101542-10101625|CRISPRCasFinder
CCGCCCGCTGGTACGAGGACCAGGTCG	ACGCAGCGACCTCGTGGCACGGTGTCAGCA
CCGCCCGCTGGCACGAGGACCAGGTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_097287820.1\|10113141_10113846_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP041607.1\|WP_143604157.1\|10112598_10113021_+\|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl\|CDD\|377399
NZ_CP041607.1\|WP_097287814.1\|10106122_10106362_+\|DUF5302-domain-containing-protein	unknown	unknown	gnl\|CDD\|379949
NZ_CP041607.1\|WP_097287810.1\|10100306_10101002_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP041607.1\|WP_143604151.1\|10097031_10098675_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP041607.1\|WP_143604150.1\|10095719_10096328_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP041607.1\|WP_143604156.1\|10111928_10112318_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054233519.1\|10091938_10092055_+\|SapB/AmfS-family-lantipeptide	unknown	unknown	gnl\|CDD\|380211
NZ_CP041607.1\|WP_097287809.1\|10096537_10096804_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604149.1\|10092261_10093974_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP041607.1\|WP_143604147.1\|10086458_10087136_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604155.1\|10106447_10106639_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604152.1\|10099902_10100109_+\|Arc-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|164855
NZ_CP041607.1\|WP_143605771.1\|10115251_10115689_-\|transposase	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604154.1\|10104671_10105571_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP041607.1\|WP_060897681.1\|10104109_10104589_-\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|224759
NZ_CP041607.1\|WP_143605770.1\|10094063_10095881_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP041607.1\|WP_143604148.1\|10089208_10091857_+\|lantipeptide-synthetase	unknown	unknown	gnl\|CDD\|271199
NZ_CP041607.1\|WP_143604158.1\|10114125_10115193_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604159.1\|10115716_10116487_-\|transposase	unknown	unknown	gnl\|CDD\|372577

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_097287820.1\|10113141_10113846_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.03394e-10
NZ_CP041607.1\|WP_143604157.1\|10112598_10113021_+\|SsgA-family-sporulation/cell-division-regulator	gnl\|CDD\|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	2.4637e-32
NZ_CP041607.1\|WP_143604148.1\|10089208_10091857_+\|lantipeptide-synthetase	gnl\|CDD\|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	2.08987e-94
NZ_CP041607.1\|WP_097287810.1\|10100306_10101002_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.77432e-09
NZ_CP041607.1\|WP_143604151.1\|10097031_10098675_+\|amino-acid-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	7.51352e-53
NZ_CP041607.1\|WP_143604150.1\|10095719_10096328_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.30575e-32
NZ_CP041607.1\|WP_054233519.1\|10091938_10092055_+\|SapB/AmfS-family-lantipeptide	gnl\|CDD\|380211	NF033212, SapB_AmfS_lanti, SapB/AmfS family lantipeptide. Members of this family are class III lantipeptide precursors. These typically are short peptides, encoded next to the gene for the lantipeptide synthetase that creates the characteristic lanthionine (or beta-methyl lanthionine) bridges for which these natural products are named. Members of this family include SapB and AmfS, which are considered morphogens rather than antibiotics. Members also include labionin-containing peptides such labyrinthopeptins A1 and A2.	1.95101e-08
NZ_CP041607.1\|WP_143604149.1\|10092261_10093974_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.11186e-92
NZ_CP041607.1\|WP_143604152.1\|10099902_10100109_+\|Arc-family-DNA-binding-protein	gnl\|CDD\|164855	PHA01513, mnt, Mnt.	7.70542e-07
NZ_CP041607.1\|WP_143604154.1\|10104671_10105571_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.3567e-26
NZ_CP041607.1\|WP_060897681.1\|10104109_10104589_-\|winged-helix-DNA-binding-protein	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	5.26349e-08
NZ_CP041607.1\|WP_143605770.1\|10094063_10095881_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.89506e-60
NZ_CP041607.1\|WP_097287814.1\|10106122_10106362_+\|DUF5302-domain-containing-protein	gnl\|CDD\|379949	pfam17227, DUF5302, Family of unknown function (DUF5302). Family of unknown function found in Actinobacteria with highly conserved motif of FRRKSG found at the C-terminus.	8.04467e-13
NZ_CP041607.1\|WP_143604159.1\|10115716_10116487_-\|transposase	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.46451e-15

>NZ_CP041607.1|WP_097287810.1|10100306_10101002_-|TetR/AcrR-family-transcriptional-regulator
MSHHHAPSASETLAKPLRRDAQRNRDAIVAAARTAFSEQGLGASLEGVAREAGVAIGTLYRHFPTRLDLVETLFNAKYTELLTTAEEAAAMDDAWEGFCRYLEKLCQLQACDRAFNDLVSARLPLHVAGRKMYERTKELGIQIMRNAQEQGVLRGDVTAQDIAFVIWSQAGIIQATRTIAPQAWRRHLHLMLDAFRTEGAHELPEPPLTSQQVDQTLVTLECTEEDCREQS
>NZ_CP041607.1|WP_143604152.1|10099902_10100109_+|Arc-family-DNA-binding-protein
MIRFSLRIPADLHEQVTARAAADRRSLNSEILHLLEVALTAPRPDAGSPSGDPASPAPLRGKPDSSPA
>NZ_CP041607.1|WP_143604151.1|10097031_10098675_+|amino-acid-permease
MASVDQLAPPSTSQNRSSLRRNVGLIGLLWASAGSIIGSGWLYGAKNAVVAAGPAALISWGIGAVAIVLLAFVHAELGGMFPVAGGTARYPHYAFGGLAGMSFGWFAWLQAATVAPIEVEAMIGYAGHWHFAKSFLNDNGTLTTSGFIVAVILMGVFVAVNFLGVSVLARTNSAATWLKIFVPLLAIFTLAATHFHSSNFTSHGFAPFGSKGVLAAISTSGIVFALLGFEQAIQLAGESRNPKRDIPRAVLGSVAIGTLIYVLLQVVFIGALPGSSFAQGWDKLDFVGISGPFAGLATLVGLGWLTVVLYFDAIVSPGGTGLIYTTSTSRISYGLSKNGYAPRVFERTDARGVPVYGLIMSFVTGVVCFLPFPSWQQLVGFITSASVLMYAGAPLAFGAMRRRLPNRERSYRLPLGGVLSPLAFIVASLIIYWSGWQTLEKLGEAIVLGYLLLGGYALYASKKGLPNAPRISWKSAQWLPVYLLGIGVISWQGTFGGGQGNLPMWTDIAVVAVFSLAIYHWAIRVALPTDAIEQNIEDIEVVDAGGH
>NZ_CP041607.1|WP_097287809.1|10096537_10096804_-|hypothetical-protein
MVPTKPWSRPAAVPLREWALRDRERRGITAAVAKGAQPRKAVPSADPDERVWRLEARGAELEASERKLATERNILRKAAKYLAGETNW
>NZ_CP041607.1|WP_143604150.1|10095719_10096328_-|response-regulator-transcription-factor
MIQVLLVHDGCLVRSVLAQWLSREPDLRVDDVPWRRASRHVRALRPDVCAADLDCSDTAGIPPLGELGLRGGGQVLSRLLVLATANRPGLLRRALEAGALGYVDKTGTPEQLLRGIRKVAKGERFVSESLGFGFLKAAEMPLTRRELSVLTLAAEGASVAEIAGSLHLSHGTVRNYMAAITRKTGARNRIDAIRISQSQGWL
>NZ_CP041607.1|WP_143605770.1|10094063_10095881_+|ATP-binding-cassette-domain-containing-protein
MVRLAGWSVLETGQTFLLGYALARALDDGFLAGRAAVGLGWLAAAGLGVLVGAYGTGRVYGAVAALVEPLRDRLVTGVVRRGVREGDRGALSGLTQQVEIARDTFAGLVMVSRSFVFTSVGALAGLCSLAPLLLLPVVPPLVAGVALFAATLRPLARRQEAYLAADEALAENLGAVCPGLRDVTAAGAEDRIAADAGALADAEQRAARALARWGVARVVCLAVGGHLPLVLLLAGTPWLLDHGVTPGAVLGALAYVSQSLLPALTGLIHGLGTSGSRLTVVLRRLTPPPPAVSRPAVTELTPHTPPPCPSTPAVPPALALTSLTFSYGPACAPVVDDLTLALPSGAHLAVVGPSGVGKSTLAGLVAGLLKPVRGDIRICGCRVPGREAAAGRVLIPQEAYVFSGRLRENLAHLRPDPVPEAELLAAAEAVGLTPLLNALGGPGASVDPATLSAGERQLIALTRAYLSSAPLVLLDEATCHLDPVAEERAERAFAARPGGTLVVVAHRISSARRAGRVLVMDGPRTAFGTHEEVLRRSPLYRDLVGGWEPGQLSQPALALGDADGVDAVAGAGLAGDGRHVVAHGPVGQVQAPGDLRDGGPLGGEG
>NZ_CP041607.1|WP_143604149.1|10092261_10093974_+|ATP-binding-cassette-domain-containing-protein
MSMDPTTGGLLTAASRHSGPRWAALCLVSVATTGAGLLLPAALGRALDLLLAHAPATRWVLICATLVLLLTGLDACETVLAGTLDARTTAFLRRRVTGHVLALGPRATLRFGPGDLVARLVGNAAQAGTAPGARAALLAALAGPVGGVVALGVIDPWLAAAFLTGAPLLTLLLRSLARDTSTCVADYQRVQGRIASALAEAVGGTRTIRAAGTADRDAERILRPLPELSRAGRRMWRVQGRAAARAVAVAPLLHLAVVAVAGMLLSRHRLSAGDVLAASRYAVLATGVGVLVGQLSGLVRARTAARRLGEVLAEPAPTHGDRSLPPDGPGHLELRGVSARRGARTVLDGVDLVVPGGTTLALVGRSGAGKSLLAALAGRLTDPDAGEVLLDGVALPALSRAELRAAVAYAFDRPALLGTTVEDTIALGLRCPSPARVREAARTACADAFVRRLPDGYATPVADAPHSGGEAQRLGLARAFAQRGRLLVLDDALSSLDTVTEHQVTEAVLGRAATGTRLVVAHRAATAARADTVAWLDGGRVRAVGTHAQLWRRLPGYRAVFGAAGEEAGA
>NZ_CP041607.1|WP_054233519.1|10091938_10092055_+|SapB/AmfS-family-lantipeptide
MALLDLQTMESDEHTGGGGNSTVSLLSCISAASVLLCL
>NZ_CP041607.1|WP_143604148.1|10089208_10091857_+|lantipeptide-synthetase
MDKRYEVYALADAHFYETPDRLATGVAGAAQGTVPVFETARRPIPEGWATARVGDWLTLTPLGADGAPAAAPAQGWKIHASATRANADRIAAIVWDYCFPRRIPFKFVPGPHLLHLRNTKYAGRDTSGKFVTVYPADEEQLHTVLRELGSLLEGFEGPYILTDLRWHDGPLYVRYGAFARMYVVDERGSLVPAVRDGSGTLVPDRRAPSFQVPEWVALPAFLEPHLAARNTTTVGELPYRIEKALHFSNGGGVYAGTDTRNGRKVVLKEGRPHAGLASDGADAIARLEREKRALEAVAGSGVVPEVRDWFTLGDHRFLVMDFVAGRPLNSFFAERHPLLSPDPDPQAVAAYTAWAVSIHRAVECAVEKVHARGIVFNDLHVFNIMVAPDEESVFLIDFAAAAPAEENGRQVVAHPGFFAPPDRRGADVDRYALACLRLALFLPVTTLLVVDRGKAAHLAEVIAQQFPDVPREFLDEAVAEITRDVCGTGAPVGGTGAPERVPSAPASRVEPGDWPHSRDSMIKAILASATPERDDRLYPGDVAQFSDGGGLGLAHGAAGVLYALAAVGAERHDEGERWLLDHTAPAPTGTPLGLYDGLAGVAHTLDLLGHRQRALDLVDGILRERWQHLSSDLQGGLAGLGLVLGRLAATTGESELHERAAEAADLLVRRLAEPAPAAPRRRAGLMRGASGPALFLLRRYEETGERALLEAAGVALRRDLECCAEREGGAVEVDEGWRTMPYLGDGSVGVGLMLDDYAAHVPDAGAEFARARAGILTAATSRFYAQPGLFQGRAGMILHLARTTAPGATRARLDEQIAGLGWSAMPYQGQLAFPGHQMMRLSMDLATGTAGALLALAAAFGSGDEGVAAHLPFLPPPHRRPL
>NZ_CP041607.1|WP_143604147.1|10086458_10087136_-|hypothetical-protein
MISKRAVTAAAVAATAAVLLASGDAYACSIGDFTAKATCDTSTGEARAAITITDKDPSGTPADITVRIRMAVGTDGETVGTGHIDHPTAAGASTTILVPWLQGYQWNVSVTAGNLVDERLTDLPISPDTPCVPATSPTSGTPTVGPAPSVSPTAGVTPTSSAAAPLASTSSAPSTSASSPVAGTRLAETGGGSDTGLIAGSAAAAIAAGTGVLFAMRRRATAGRH
>NZ_CP041607.1|WP_060897681.1|10104109_10104589_-|winged-helix-DNA-binding-protein
MPRSGADLALLLLGGFRSLADAATAELARRGYEDVRPVHDFAMRAITAGADNASELGRRLSVSKQAAAKTIAVLQERGYVARDTDPLDARRKRLEVTALGFEVLRQGESIFDELRDQWERQIGSAELASLEAHLATLVGALPVRLDAPGWIAHDLGGPA
>NZ_CP041607.1|WP_143604154.1|10104671_10105571_+|alpha/beta-fold-hydrolase
MNATPAGATLPGITHHRVEVNGTTLHYVAAGTSGTPILLVHGFPETWWAFHKLIPLLAERHRVFAVDLRGFGDSGNGPGEYDSATSAEDLHLLIEQLDVGPVHLTGQDISGATVFRLATTHPHDVLSFIAIETGLPGFGVEALADITHGGAWYIGVLAAPGIPEMLLAGREREFLGQFAFSATSATPDASTDADIDEFVRSYARPDGWRGAIGLYRSMLREGSEIKALADAPGLTVPVLAVGAGGRSFTAATMTQAAAATEVSSVSLDGVGHYAAMEAPDELAKAILEFVGNIDAAQRF
>NZ_CP041607.1|WP_097287814.1|10106122_10106362_+|DUF5302-domain-containing-protein
MTAEPSPQEGSELADIEEPAPAPDDGQDDLKRKFRDALARKRGMQADAAALAANTGASKIRGAHGPAASQRSFRRKSGG
>NZ_CP041607.1|WP_143604155.1|10106447_10106639_-|hypothetical-protein
MISLDAGSGDRLALAVLVQYRMATTEQMTADQDLPCGPPAGVVAIPGHGLCRTCAAKASPDGS
>NZ_CP041607.1|WP_143604156.1|10111928_10112318_+|hypothetical-protein
MNKWIKRVSTAVASTALAGGALLGVSGTASAATASAPGEHTQSAITAFTTGGDRASGYQSTHHGAQGDGWGAPRGWYTNDDRQGHYGEERWNGSHLYVWDGYRWGEVTTYRVSAERWYLDQVAWSADQH
>NZ_CP041607.1|WP_143604157.1|10112598_10113021_+|SsgA-family-sporulation/cell-division-regulator
MRSVRTVAHELPVRLVLSHDLSVSIPAALQYDADDPYAVRAVFHPLDQSGTVEWFLSRDMLAQALSEHTGHADVRMWPTSDSGRDVVRMVLSSPAGSALLELPAQGVESFLRETRSAVPPGTESSRCDLDAELAQLLAEN
>NZ_CP041607.1|WP_097287820.1|10113141_10113846_-|TetR/AcrR-family-transcriptional-regulator
MSHQHVLSAPQAPAKPLRRDAQRNRDAIVAAARKAFAEQGLDASLEGVAREAGVAIGTVYRHFPRRLDLVEELFTAKFTDLLAAAEEAAAMDDAWEGFCSYLEKLCELQACDRAFNDLVSARLPVHALGRGMFERTKERVAQIFRNAQEQGVLRDDVTPEDIAFVIWSQVGIIQATRAVAPNAWRRHLHLLLDAFRAECAHELPEPALTPQQFAQTLTTLECPEEECRECRDEA
>NZ_CP041607.1|WP_143604158.1|10114125_10115193_+|hypothetical-protein
MDVFACAGCGTELTAPVSRVALPVHVHHGGWEELHPPLMEPATYAVDPQPTGPPWRLWKEVGADAAARQGVFAPVYSVSFGARNRIVIAPGDSRSMTLIPDKCEGYCQGVDGRAGPNLACEGCGRAVATRMDDCGMWQTVWLEPDAVARRSSGLSAGPSPDWDDLERAEYRVPPVEPDGSWSRRWEAAVGVALAHLVAVTEDRPVSLPVGPVAELLGHAVGRYLPAGPGVRSVGLAGPGIHLPRPRPDVLLVPRHPLTAAPWRPPGDEGAVVPLDSGVWAYLAHPGETSPLPATGVLPEGVLRDDYPLPSRPWCPLTPHHRAFEDTLVRLPAVRAPRLRRYREAYRQAVSPASAG
>NZ_CP041607.1|WP_143605771.1|10115251_10115689_-|transposase
MQHHGLLQHALGRSRGWLTTKIRLVADGRCRPLAFLLTGGQANDAPAFTEVMARLRVPRRRGRPRTRPDVVLADRPIRRARSASTCAAVVSARTSRSGRNQGTHRLRRGSRGGCPLAFDREAYKQRNTVERCINRLQQWRGISTR
>NZ_CP041607.1|WP_143604159.1|10115716_10116487_-|transposase
MAGVLRAGPLWMETFTGLRMKQFERLLKVVRERGGDGPRIGRPWCLPLADRVLVVAVYYRTNLTMRQLAPLFGVSPATVCRVIQRLRPLLALEPASRPVDAADRLWIVDGTLVPVRDRKVGASSRNYRFSANVQVIIDAHTRLVVATARPAPGNRADAHVWRDSVLPEQCKGVTVLGDGVSINTGLVVPHRKRPGRPLPAGEEADNAEHRRVRARVEHAIGRLKNYKILRDCRQHGDGLHHAVRAVAHMHNLALAA

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Crispr_ID: NZ_CP041607_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_22

11130773-11130984

Orphan

Consensus_repeat	Method
CGACCCACCTCCGCTGGCGCGGAGAGCAC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP041607_22

>merge|NZ_CP041607|22|11130773-11130984|CRISPRCasFinder
CGACCTACCTCCGCTCGCGCGGAGAGCACCACCTGTCTACGGGGTCACGGCCCCGGGTGTTCGACCCACCTCCGCTGGCGCGGAGAGCACCCCGAGATCCTCCAGCAGGGAAAGTTGAAGCCCGACCCACCTCCGCTGGCGCGTAGAGCACGACGTGCCCTGGGCCTGGGCCTCGATCGACAGCGACCCACCTCCGCTCCAGCGGAGGTGAA

>NZ_CP041607|22|21|11130773-11130984|CRISPRCasFinder
CGACCTACCTCCGCTCGCGCGGAGAGCAC	CACCTGTCTACGGGGTCACGGCCCCGGGTGTT
CGACCCACCTCCGCTGGCGCGGAGAGCAC	CCCGAGATCCTCCAGCAGGGAAAGTTGAAGCC
CGACCCACCTCCGCTGGCGCGTAGAGCAC	GACGTGCCCTGGGCCTGGGCCTCGATCGACAG
CGACCCACCTCCGCTCCAGCGGAGGTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143604749.1\|11142653_11144090_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143457
NZ_CP041607.1\|WP_143604745.1\|11134829_11135492_-\|arsenate-reductase-ArsC	unknown	unknown	gnl\|CDD\|319973
NZ_CP041607.1\|WP_143604734.1\|11119032_11119668_-\|3-oxoacid-CoA-transferase-subunit-B	unknown	unknown	gnl\|CDD\|188219
NZ_CP041607.1\|WP_097282087.1\|11131147_11132164_-\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NZ_CP041607.1\|WP_143604744.1\|11132646_11133585_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP041607.1\|WP_143604750.1\|11144163_11145789_+\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NZ_CP041607.1\|WP_143604738.1\|11123269_11124304_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|368185
NZ_CP041607.1\|WP_143604742.1\|11127701_11128646_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_CP041607.1\|WP_143604747.1\|11137725_11138709_-\|AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP041607.1\|WP_143604748.1\|11139321_11140941_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238625
NZ_CP041607.1\|WP_143604746.1\|11135947_11136193_-\|DUF2283-domain-containing-protein	unknown	unknown	gnl\|CDD\|378367
NZ_CP041607.1\|WP_143604743.1\|11128758_11130042_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341026
NZ_CP041607.1\|WP_143604735.1\|11119664_11120447_-\|3-oxoacid-CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
NZ_CP041607.1\|WP_097282082.1\|11141597_11142218_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP041607.1\|WP_143605845.1\|11133883_11134675_+\|transposase	unknown	unknown	gnl\|CDD\|372577
NZ_CP041607.1\|WP_143604737.1\|11122295_11123258_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|319904
NZ_CP041607.1\|WP_143604740.1\|11125590_11126571_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|377240
NZ_CP041607.1\|WP_143604739.1\|11124300_11125470_-\|2-polyprenyl-6-methoxyphenol-hydroxylase	unknown	unknown	gnl\|CDD\|235874
NZ_CP041607.1\|WP_143604741.1\|11126567_11127566_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|376566
NZ_CP041607.1\|WP_143604736.1\|11121232_11122207_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|376566

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143604749.1\|11142653_11144090_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
NZ_CP041607.1\|WP_143604745.1\|11134829_11135492_-\|arsenate-reductase-ArsC	gnl\|CDD\|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	2.88515e-41
NZ_CP041607.1\|WP_143604734.1\|11119032_11119668_-\|3-oxoacid-CoA-transferase-subunit-B	gnl\|CDD\|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	1.16388e-123
NZ_CP041607.1\|WP_097282087.1\|11131147_11132164_-\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NZ_CP041607.1\|WP_143604744.1\|11132646_11133585_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.12286e-32
NZ_CP041607.1\|WP_143604750.1\|11144163_11145789_+\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_CP041607.1\|WP_143604738.1\|11123269_11124304_-\|amidohydrolase-family-protein	gnl\|CDD\|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	5.97661e-30
NZ_CP041607.1\|WP_143604742.1\|11127701_11128646_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.31347e-37
NZ_CP041607.1\|WP_143604747.1\|11137725_11138709_-\|AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	3.20308e-12
NZ_CP041607.1\|WP_143604748.1\|11139321_11140941_+\|amidohydrolase-family-protein	gnl\|CDD\|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	3.48419e-122
NZ_CP041607.1\|WP_143604746.1\|11135947_11136193_-\|DUF2283-domain-containing-protein	gnl\|CDD\|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	1.04094e-11
NZ_CP041607.1\|WP_143604743.1\|11128758_11130042_+\|MFS-transporter	gnl\|CDD\|341026	cd17473, MFS_arabinose_efflux_permease_like, Putative arabinose efflux permease family transporters of the Major Facilitator Superfamily. This family includes a group of putative arabinose efflux permease family transporters, such as alpha proteobacterium quinolone resistance protein NorA (characterized Staphylococcus aureus Quinolone resistance protein NorA belongs to a different group), Desulfovibrio dechloracetivorans bacillibactin exporter, Vibrio aerogenes antiseptic resistance protein. The biological function of those transporters remain unclear. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.90704e-95
NZ_CP041607.1\|WP_143604735.1\|11119664_11120447_-\|3-oxoacid-CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	3.95501e-97
NZ_CP041607.1\|WP_097282082.1\|11141597_11142218_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.25277e-08
NZ_CP041607.1\|WP_143605845.1\|11133883_11134675_+\|transposase	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.59219e-16
NZ_CP041607.1\|WP_143604737.1\|11122295_11123258_-\|oxidoreductase	gnl\|CDD\|319904	cd07239, BphC5-RK37_C_like, C-terminal, catalytic domain of BphC5 (2,3-dihydroxybiphenyl 1,2-dioxygenase). 2,3-dihydroxybiphenyl 1,2-dioxygenase (BphC) catalyzes the extradiol ring cleavage reaction of 2,3-dihydroxybiphenyl, the third step in the polychlorinated biphenyls (PCBs) degradation pathway (bph pathway). The enzyme contains a N-terminal and a C-terminal domain of similar structure fold, resulting from an ancient gene duplication. BphC belongs to the type I extradiol dioxygenase family, which requires a metal in the active site for its catalytic activity. Polychlorinated biphenyl degrading bacteria demonstrate multiplicity of BphCs. Bacterium Rhodococcus rhodochrous K37 has eight genes encoding BphC enzymes. This family includes the C-terminal domain of BphC5-RrK37. The crystal structure of the protein from Novosphingobium aromaticivorans has a Mn(II)in the active site, although most proteins of type I extradiol dioxygenases are activated by Fe(II).	1.99741e-82
NZ_CP041607.1\|WP_143604740.1\|11125590_11126571_-\|cyclase-family-protein	gnl\|CDD\|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	9.48391e-17
NZ_CP041607.1\|WP_143604739.1\|11124300_11125470_-\|2-polyprenyl-6-methoxyphenol-hydroxylase	gnl\|CDD\|235874	PRK06847, PRK06847, hypothetical protein; Provisional.	7.33069e-175
NZ_CP041607.1\|WP_143604741.1\|11126567_11127566_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|376566	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family. This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. FAA is the last enzyme in the tyrosine catabolic pathway, it hydrolyzes fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle. Mutations in FAA cause type I tyrosinemia in humans this is an inherited disorder mainly affecting the liver leading to liver cirrhosis, hepatocellular carcinoma, renal tubular damages and neurologic crises amongst other symptoms. The enzymatic defect causes the toxic accumulation of phenylalanine/tyrosine catabolites. The E. coli W enzyme HHDD isomerase/OPET decarboxylase contains two copies of this domain and functions in fourth and fifth steps of the homoprotocatechuate pathway; here it decarboxylates OPET to HHDD and isomerises this to OHED. The final products of this pathway are pyruvic acid and succinic semialdehyde. This family also includes various hydratases and 4-oxalocrotonate decarboxylases which are involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. 2-hydroxypentadienoic acid hydratase encoded by mhpD in E. coli is involved in the phenylpropionic acid pathway of E. coli and catalyzes the conversion of 2-hydroxy pentadienoate to 4-hydroxy-2-keto-pentanoate and uses a Mn2+ co-factor. OHED hydratase encoded by hpcG in E. coli is involved in the homoprotocatechuic acid (HPC) catabolism. XylI in P. putida is a 4-Oxalocrotonate decarboxylase.	1.62891e-73
NZ_CP041607.1\|WP_143604736.1\|11121232_11122207_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|376566	pfam01557, FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family. This family consists of fumarylacetoacetate (FAA) hydrolase, or fumarylacetoacetate hydrolase (FAH) and it also includes HHDD isomerase/OPET decarboxylase from E. coli strain W. FAA is the last enzyme in the tyrosine catabolic pathway, it hydrolyzes fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle. Mutations in FAA cause type I tyrosinemia in humans this is an inherited disorder mainly affecting the liver leading to liver cirrhosis, hepatocellular carcinoma, renal tubular damages and neurologic crises amongst other symptoms. The enzymatic defect causes the toxic accumulation of phenylalanine/tyrosine catabolites. The E. coli W enzyme HHDD isomerase/OPET decarboxylase contains two copies of this domain and functions in fourth and fifth steps of the homoprotocatechuate pathway; here it decarboxylates OPET to HHDD and isomerises this to OHED. The final products of this pathway are pyruvic acid and succinic semialdehyde. This family also includes various hydratases and 4-oxalocrotonate decarboxylases which are involved in the bacterial meta-cleavage pathways for degradation of aromatic compounds. 2-hydroxypentadienoic acid hydratase encoded by mhpD in E. coli is involved in the phenylpropionic acid pathway of E. coli and catalyzes the conversion of 2-hydroxy pentadienoate to 4-hydroxy-2-keto-pentanoate and uses a Mn2+ co-factor. OHED hydratase encoded by hpcG in E. coli is involved in the homoprotocatechuic acid (HPC) catabolism. XylI in P. putida is a 4-Oxalocrotonate decarboxylase.	5.76597e-70

>NZ_CP041607.1|WP_143604743.1|11128758_11130042_+|MFS-transporter
MPSSVPSPSSPPAPAESAQPPFATLPTSGAAHRLRVALLMAGSCLPILGAVLIAPVLPKMQEHFADVPGAAALVPMALTVPALALGLLAPFAGVIVDRLGRKRLLIVATVLYAVFGTAPLWLKSLGAIVASRALVGIAEAAIMTCCTTLIGDYYTGRVRDRYLALQTMCASASATAFFVIGGAAGSAGWRTPFWIYAVSLLIAPLMAIGLPKPTAATGAAAEDGEGTDTTAVPKRSFPFRQLAGICGLTMFGALVFYTVPVEMAYLLDDLGVTATSVIGPATSIASAATVAGAITFAKLRGAPGPRLPLVFALCAAGFAVMWLANSAPLLIAGAVLNCLGTGLLLPSLLTIAMSKLDFSDRGRGTGLWTASFFIGQFICPLVLIAAESALGTLAAAVGLLGLASAVIAAGLLLAARRGAAALAPLPQ
>NZ_CP041607.1|WP_143604742.1|11127701_11128646_+|LysR-family-transcriptional-regulator
MNLASLDLNLVVALRALLEERNVTRAGRRIGLSQPAMSAALARLRRHFDDDLLSRVGGRYELTALGLALLDRTVTACDLLERVFTSQAVFDPAHEEHEFTLLASDYAVAVFGADLARVVHTEAPGVRLRFRQSPTDITENTGALLSTADGLLLPHGIIGDFPAVELYRDRWVYLVADDNPEVGERLTLDDLARLPWVTYQRTYDAPAARQIGMLGIEPHVEVSVDSFQLMPLLVAGTRRVALIQGHLADRLDGLVPVRVMEPPYDAVPLREALWWHPVHTHDAAHIWLRETAARVAETIHGKDDRDPADRSDRG
>NZ_CP041607.1|WP_143604741.1|11126567_11127566_-|fumarylacetoacetate-hydrolase-family-protein
MKSAAASAPLFAGPFAIGTLSAPGGTAFPGLAVPDGRVLDLRTALAEPALTTLALLERWDEELPRLHGFAGDPAGDWLPLDSLSVHAPVEPRQIFQSGANYRQHVIDLEVAHRAPDDPRTVEEARAEIAAIMDKRAAEDLPYVFIGLPTTITGPYDDVVLPSWAKKPDWELELAAVISRPAYRVTVEEALDHVAGYTIANDLTDRATVFRRDMPAIGTDWLRCKNAPGFTPLGPWIVPTGSVADPSDLRVTLKLNGDTMQDESTKDMIFGVARLVSYISQTAQLLPGDLVLTGSPAGNGIHWGRLLRDGDVMDGSVTGLGAQRTHCVAEEAP
>NZ_CP041607.1|WP_143604740.1|11125590_11126571_-|cyclase-family-protein
MSDHATTVPDAKDAEGTIAEAAKAYSNWGRWGADDVLGTLNFLDADKRREGAALVRDGVSFSLSQRFDMNGPQKGWRRRTNPVHTMLDTGTDAALGNQGFPHGIGGADDVIAMPLQCSTQWDGLGHIFDHGKAWNGRAAEKVVTSDGDLVTGIEHMAPYVAGRGVLLDVGLVVGRDGELPDGFAITEEHLTATAEAHGVTVGRGDLVLVRTGRLARARRDGWGEYAGGPSPGLSFTTAGWLHRSEIAGIATDTWGFEVRPNEFDHAFQPLHQVAIPNMGLLIGEMWDLDALAEHCAADGRYEFWLTAAPLPITGAVGSPVNPIAVK
>NZ_CP041607.1|WP_143604739.1|11124300_11125470_-|2-polyprenyl-6-methoxyphenol-hydroxylase
MTDPRPRSRPRTVLVIGGGASGNAVTVLLRRAGITVDLIEARPDWNVLGSGITLQGNALRVLRELGVWDKVRESGYAFDSVGLATPDGHVFHVQQDIRTGGTDLPATIGMRRPRLQEILCEAVRASGATVHLGTTADELVQDSAGVTARFSDGTEGRYDLVVAADGLNSATRAMIGFSEKPEPTGMAIWRVAAPRPAGVERTDLAYGGPCYIAGYCPTGENTIYAYLVEANRDRASIDPASYADEMRRLAAPYGGAWPEIAASITDPAKVNYTWFDRLLVEGPWHRGRVVLIGDAAHACPPTLAQGAAMSLEDASVLAELLSAEESWDSPGSPGSLDNLLTRYHERRIDRVRMVVEASMQLGQWQLDGVRDADVPGLIGRTMSVLKETP
>NZ_CP041607.1|WP_143604738.1|11123269_11124304_-|amidohydrolase-family-protein
MTTPDTPDALATSAIPTIDVHAHVLLPHVEQAVAGHPGLDAARALDARRNGPDALAVSGPMVRDRIPQLTDVKARLTAMDASGVDVQLVSPSPSHYHYWADEDLARTVWELANTGTAAHVAQAPDRLHGLGLVPLQHPDLAVEALDHALGLGLRGVEISSHAPGRELSDPAYDTFWALAETTGAVLFLHPFGCTLDERLNRWYLSNTVGQPTENAVALSHLIFSGVLDRHPGLKVIAAHGGGYLPTHIGRSDHAWRARPDTRGCVSEPSSYLRRLYFDSLVHDPHVLRELIRVAGPHRVLLGSDFPFDMGTEDPVGALRAATDLPDPHFHAVRGGTAAALLRLS
>NZ_CP041607.1|WP_143604737.1|11122295_11123258_-|oxidoreductase
MTNDLPNPLPNRLLTHLRHVDLAVPDYDKQLDFYAGVWGLTKVAEDSGISFLAAEGSPESYVVRLRKADEKRLDLVSYGAASAADVDTLAEQLLADRARLISQPGKVDTPGGGYGFRFFDGDGRTVEVSAEVEARQHRRIEEKEAIPVRLSHVVLNSPDLDATRSWYERHLGFRLSDTLSSPHMGQVMHFMRISSQHHSMAIAKGPHTSLHHVSFELRGLDEYMRGSGRVMRSGARKIWGPGRHMAGDNTFTYFLDPHGNTVEYTTELEELDEDTWHPHVYDFSRPEVTDQWGTANPMNELIAKESFNDVDPGVFVAPPV
>NZ_CP041607.1|WP_143604736.1|11121232_11122207_-|fumarylacetoacetate-hydrolase-family-protein
MRFATYEHHGRRSVATVDDDGTLHPVPGHDSLLDLLRAGPEALREAGNATLDAPDVPGCPHVSEVRLLPPLQPPSVRDFVTFEEHVEGVRRSIDNAAGVPDAWYDAPTFYFTNPYAVIGPHDDVPVPPGSSVLDFELEVAAVIGVEGRDLTPEQARDHIIGYTIFNDWSARDLQSAEMKVGLGPCKGKDTAATLGPYLVTADELEPYRDRDGFLRLALTASVNGEVVGEDLLSNMSWTFEEMAAYASRGTYVRPGDVLGSGTCGNGGCLAELWGVRGRQDPPPLKPGDTLTLTVEGIGTVSNTVVPGAGPIPIPRARKRPRLRP
>NZ_CP041607.1|WP_143604735.1|11119664_11120447_-|3-oxoacid-CoA-transferase-subunit-A
MNKVSASAAAAVADIPDGASLAVGGFGLSGIPATLIDALHAQGATGLKVVSNNCGVDGRGLGVLLAEGRVNRVTGSYVGENKEFARQYLSGELEVELVPQGTLAERLRAGGAGIPAFYTPAGVGTQVADGGLPWRHAADGSIAVASPAKESRTFGGRNHVLEHGITTDYALVHAWRGDTHGNLVFNKAADNFNPLAAMAGRITIAEVEELVEPGALGPDAIHVPGIFVQRVVALAPAQAADKHIEHLRISASSTRGTVRT
>NZ_CP041607.1|WP_143604734.1|11119032_11119668_-|3-oxoacid-CoA-transferase-subunit-B
MSWTRDQMAARAAAELSDGSYVNLGIGLPTLIPGHLPPGVHVVLHSENGILGTGPYPREHEVDPDLINAGKETVTVLPGASFFDSALSFGMIRGGHIGTAVLGAMQVSATGDLANWMIPGKMVKGMGGAMDLVHGARRVIVLMDHTAKDGSPKILDECTLPLTGRACVHRVITDLGVIDVTDSGLLLVEAAPGVTPEAITAATAAKLHTAT
>NZ_CP041607.1|WP_097282087.1|11131147_11132164_-|DNA-directed-RNA-polymerase-subunit-alpha
MLIAQRPSLTEEVVDEFRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDLILNIKQLVVSSEQDEPVVMYLRKQGPGLVTAADIAPPAGVEVHNPDLVLATLNGKGKLEMELTVERGRGYVSAVQNKQVGQEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVETKQAMRPRDAMASAGKTLVELFGLARELNIDAEGIDMGPSPVDAALAADLVLPIEELELTVRSYNCLKREGVHSVGELVARSEADLLDIRNFGAKSIDEVKAKLAGMGLGLKDSPPGFDPTAAALGADDGADAGFVETEQY
>NZ_CP041607.1|WP_143604744.1|11132646_11133585_+|alpha/beta-fold-hydrolase
MPSRGARTLSTINTGLPEGCEERFVALEHHYDDIEQIRMHWVTAGAGDPVVLLHGWPQTWYEWRHLIPVLAERHLVIAPDLRGWGETERPADGYDVATAAADVRHLLDHLGIASAHVIGHDWGTPIGYYLAATARDRVVSFTALEASIPGAGGEDLLNFSRAWNPLWFFPFLATPELPQQLIGGGGQETFFTWMLTQMCRATPGSLTDEDIAVYVKAYSDDDAVRSSCAYYVNTWASADQVRAAAQVPLNVPVLAIAGERSLGQNMIDFVRRLAPDAEGVILPGCGHLVPEERPAELAQLVTNFLAGIDSHG
>NZ_CP041607.1|WP_143605845.1|11133883_11134675_+|transposase
MFTDRVLVTLVHLRTQLPHAALAQLYGVGRFTVTEAIGEMRPLLAARGFAVPDRPGLRLRTLADVFAYAEAEGVILRIDGTETQVRRPQANRPGRRAFVSGKKKQNTIKTTTISDGQGSTLFSGAVRPGRMHDQTAMRTEGIAEHLRLHPTVKAEVDEGYRGLANEFPHQVSAPPRKRKADASLGDQHAWREIRRRQSSRRICVEHTNAEYKQWRPLQRYLGHREHYADDHRAIASLVSDRAAQRPTARKPSTELVLVRTVAC
>NZ_CP041607.1|WP_143604745.1|11134829_11135492_-|arsenate-reductase-ArsC
MTGTASTPPRNLSIDQQLALRTAATHLSREFDGIFGQETIERFLHTSYDQFAGRRTIPNFLPLIAERFARQRLRALAKVEDHHTDGKPVLLFLCVHNAGRSQMAMGFFQHLAGDNAVAWSGGFEPDFEFNPSAIAAMSERGIDISREFARPWTDEVVRAADVVVSMGCGDACPVFPGKRYLDWTLDDPAGKAVDDVRPIRDDIERRVRGLLDDLGVPAQH
>NZ_CP041607.1|WP_143604746.1|11135947_11136193_-|DUF2283-domain-containing-protein
MTDVRVTYDKSVNAAYIYLTDPQAHVKSARMYPCDPVDVDGMINLDFDEQGRLIGIEVLAASSKLPEYLLQSAERLDTEGA
>NZ_CP041607.1|WP_143604747.1|11137725_11138709_-|AsnC-family-transcriptional-regulator
MPKVRQDLDAVDRRITAVLLASPRASWRHVADVLGVSERTVVRRAAPLFHDQTLRATAVRNPALYPHLIPMVLRIRCRPNRITAIAATLARRRDTVWVDILGGGDEICAVLFLNGPDARNELVLRDLPATAAVQSWTSYDLLKVFPAGFAWSAGLLTQEESAQLWPGFDASPEPLSPLPEDDVLIDALIEDSRMTYEELASRTGKTPRTVRRRQDALVEAHAVRLATEVDLALLGVHAEALLWIKAMPGALQETGQILSRHPQVRFTAATTGSSSLLVAVAAADLSALYTFLTGTVGALPHISDIEVTPILTGVKRTGLVRPAALSL
>NZ_CP041607.1|WP_143604748.1|11139321_11140941_+|amidohydrolase-family-protein
MTDHGADLVIRADAVHTLVPGRAPQRALAVRGDRIAALSPDPNGLDHWVTARTTVHDLPGATVLPAFDDTHTHLIYAALGAQDVPVHQARTISEFLDLIRQRAEVTPEGEWIRTTTNWQELNLAERRMPTAAELDRATDRHPVLVKRGGHNDVVNTYALRLAGITEDTPVPPGGVIGRDADGRLDGRLIDNALGLVERLVPAPDRSQRIDGLRLATSQYAATGIGSVRDCAVTPEDYRVLLAAREAGALSTRVRTLISALGMTSAAQVEDLLDVMEEWRYSSDPWLRVWGVKFGLDGGLEAGATEEPYACDHSFSGTLTWEPGALVEAVEAVVRRGWRVGTHAYGDRAVRILLDVYERVLARNPGLPVGTLVMEHGGLAGPEQRARAVELGIPVTIQQPLLHDTAEVEEGFWGPERVARLFPARGWIDLGAQVSAGSDFPVGQFGAMRSVWGMTTRQTVIGVKGPEHAITYQEALALHTTNAARLCGEESLRGTLTPGRFADLTVWDRDPAHCPSDALRDLNPIRTIVGGLLVTSADAH
>NZ_CP041607.1|WP_097282082.1|11141597_11142218_-|TetR/AcrR-family-transcriptional-regulator
MRTYGGATAEQRTSLRRQRLMESGLELFSSQGYAHTSISAVLRHAGLKDRYFTESFSSLDDLMAALMRDIYEEQITRCTEAIGTDQPLRDRARNMIDVIVGLPLQDPRKGRVKLAESLGAGPLTARERRLGLQRMSGLVDSLLREGLHDPRIDTATMSVAVVGAVSEMLLSWFNGVLDISREELVDQGLLLFEAITCMPGDAPSAA
>NZ_CP041607.1|WP_143604749.1|11142653_11144090_+|aldehyde-dehydrogenase-family-protein
MNPNHLFIGGRWVHTSGDRVINVVSASTGDHLGAVPDGSQGDIDRAVGAARAAFDPPTGWASWGTERRAAAMIRLADALDARKGATSDAVSAQNGMPITVARSFEGVVPSALLRYYAGLADSMPCEELRTGLPRGTTLVRREPAGVVAAIMTWNFPQTIAFFKIAPALAAGCVLVLKPAPETVLDSVLLAEAVKEAGIPDGVINIVPGGRDTGAYLVSHPGVDKVSFTGSTRAGRQVASTCAELLRPVTLELGGKSAAVVLDDADLAANAEQFFMASLLNNGQTCYASTRILASRSRYREVVEFCTAMARDAVVGDALDPDTQIGPLVSLRQRERVLGYIKTGLNEGARLTTGGGRPPGLDRGWFVEPTVFADVENSSTIAQEEIFGPVLTITSYDGEDEAVRLANESAYGLAGTVWTTDVDHGAQVARRIRTGTVGLNGYLPDLTSPYGGRKASGLGSELGPEGLHAYQQVQSIYHP
>NZ_CP041607.1|WP_143604750.1|11144163_11145789_+|choline-dehydrogenase
MTSTGTEGFDYVIVGAGSAGCVLADRLSRDDRVRVLLLEAGGPDTDELIHIPAALGMLFGSHSDWSYRTVEQPQPGRTFSWPRGKTLGGSSSTNVMIYTRGNRHDYDGWRDEYGARGWGYDDVLPYFVKSESNRRLGEPYHGSDGPLHVEDRVYTHELSRSWLDAAVEWGLDRTDDFAGESPVGAGLYQVTCHHGRRWSAADAYLRPALDRPNLTVRTGALATKITLDGSRAAGVTYLRDGQERAAHADREILLCGGSINSPQLLLLSGIGDPDELHDVGIDVRVPLPGVGRNLQDHLMAPVVWDTRNSTDIVRDLLTPDNLERWRAHGDGPFASNYGEVGAFLNVTDGNSRPDVQLVGGATALILSGEEVPDRPVFTMNCCPLNPRTRGTVRLASADPQAPPLIDPRYFDVPADVSVMVAGLRAVIGIAHCAPFAAYLARAYLPASDDLDCLDGMDDAALEEHVRRWSATSYHPVGTCAMGTGDDSVVNADLEVYGVERLRVVDASVMPTVISGNTNAPTIMIAERAAELIGERRRRQSG

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Crispr_ID: NZ_CP041607_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041607_23

11451284-11451502

TypeV-U3,TypeV-U4?

Consensus_repeat	Method
GGCGGCGACGGTGTCATCGGCGGCAACGGAGGCAAGGGCGGCAACGGCGGC	PILER-CR

2 spacers

c2c10_CAS-V-U3

The CRISPR arrays of NZ_CP041607_23

>merge|NZ_CP041607|23|11451284-11451502|PILER-CR
TCGGCGGCAACGGAGGCAAGGGCGGCAACGGAGGCGACGGCATCCTGTCCGGCGGTGGTGGCGGCGGCGGTGGTGGCGGCGGCGACGGTGTCATCGGCGGCAACGGAGGCAAGGGCGGTGACGGCGGCACCGGCCTGTTCGGCGGCAGCGCCGGCTCCGGCGGCTCCGGCGGCGACGGTGTCATCGGCGGCAACGGAGGCAAGGGCGGCAACGGCGGCT

>NZ_CP041607|23|2|11451284-11451502|PILER-CR
TCGGCGGCAACGGAGGCAAGGGCGGCAACGGAGGCGACGGCATCCTGTCCGG	CGGTGGTGGCGGCGGCGGTGGTGGCGGCGGCGACGGTGTCAT
CGGCGGCAACGGAGGCAAGGGCGGTGACGGCGGCACCGGCCTGTTCGGCGGC	AGCGCCGGCTCCGGCGGCTCCGGCGGCGACGGTGTCATC
GGCGGCAACGGAGGCAAGGGCGGCAACGGCGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041607.1\|WP_143604920.1\|11441879_11442548_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380313
NZ_CP041607.1\|WP_143604921.1\|11443258_11443852_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604924.1\|11452380_11452989_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_143604928.1\|11460550_11461492_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|181818
NZ_CP041607.1\|WP_143604929.1\|11461751_11463632_+\|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl\|CDD\|225922
NZ_CP041607.1\|WP_143604925.1\|11453126_11454362_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|369272
NZ_CP041607.1\|WP_143605864.1\|11459588_11460467_-\|NAD-dependent-epimerase	unknown	unknown	gnl\|CDD\|187540
NZ_CP041607.1\|WP_097281907.1\|11447598_11448651_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP041607.1\|WP_143604919.1\|11441083_11441734_-\|FMN-dependent-NADH-azoreductase	unknown	unknown	gnl\|CDD\|224103
NZ_CP041607.1\|WP_143604923.1\|11451771_11452227_+\|DUF1153-domain-containing-protein	unknown	unknown	gnl\|CDD\|366690
NZ_CP041607.1\|WP_143604918.1\|11438638_11440150_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380463
NZ_CP041607.1\|WP_143604922.1\|11444186_11445524_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|223594
NZ_CP041607.1\|WP_143604916.1\|11435501_11435963_-\|DUF2871-family-protein	unknown	unknown	gnl\|CDD\|378551
NZ_CP041607.1\|WP_143604915.1\|11434826_11435432_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP041607.1\|WP_143604926.1\|11455538_11458142_-\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|369272
NZ_CP041607.1\|WP_075032243.1\|11440436_11440922_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP041607.1\|WP_143604927.1\|11458450_11458681_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|99777
NZ_CP041607.1\|WP_095849905.1\|11464588_11464912_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041607.1\|WP_054228623.1\|11463874_11464534_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP041607.1\|WP_143604917.1\|11437222_11438380_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c10_CAS-V-U3	-	gnl\|CDD\|223747

Protein	Function_ID	Function_description	E-value
NZ_CP041607.1\|WP_143604920.1\|11441879_11442548_+\|nitroreductase	gnl\|CDD\|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	9.27927e-53
NZ_CP041607.1\|WP_143604916.1\|11435501_11435963_-\|DUF2871-family-protein	gnl\|CDD\|378551	pfam11070, DUF2871, Protein of unknown function (DUF2871). This family of proteins has no known function.	1.12335e-56
NZ_CP041607.1\|WP_143604928.1\|11460550_11461492_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.55461e-106
NZ_CP041607.1\|WP_143604929.1\|11461751_11463632_+\|glycoside-hydrolase-family-15-protein	gnl\|CDD\|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	1.34409e-124
NZ_CP041607.1\|WP_143604925.1\|11453126_11454362_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.00985e-48
NZ_CP041607.1\|WP_143605864.1\|11459588_11460467_-\|NAD-dependent-epimerase	gnl\|CDD\|187540	cd05229, SDR_a3, atypical (a) SDRs, subgroup 3. These atypical SDR family members of unknown function have a glycine-rich NAD(P)-binding motif consensus that is very similar to the extended SDRs, GXXGXXG. Generally, this group has poor conservation of the active site tetrad, However, individual sequences do contain matches to the YXXXK active site motif, and generally Tyr or Asn in place of the upstream Ser found in most SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.20589e-63
NZ_CP041607.1\|WP_097281907.1\|11447598_11448651_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.89889e-108
NZ_CP041607.1\|WP_143604919.1\|11441083_11441734_-\|FMN-dependent-NADH-azoreductase	gnl\|CDD\|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	1.03251e-44
NZ_CP041607.1\|WP_143604923.1\|11451771_11452227_+\|DUF1153-domain-containing-protein	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.00252898
NZ_CP041607.1\|WP_143604918.1\|11438638_11440150_-\|hypothetical-protein	gnl\|CDD\|380463	cd19540, LCL_NRPS-like, LCL-type Condensation domain of nonribosomal peptide synthetases (NRPSs) and similar domains. LCL-type Condensation (C) domains catalyze peptide bond formation between two L-amino acids, ((L)C(L)). C-domains of NRPSs catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). In addition to the LCL-type, there are various subtypes of C-domains such as the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity. An HHxx[SAG]DGxSx(6)[ED] motif is characteristic of LCL-type C-domains.	3.50257e-42
NZ_CP041607.1\|WP_143604922.1\|11444186_11445524_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|223594	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones].	6.93178e-36
NZ_CP041607.1\|WP_143604915.1\|11434826_11435432_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.85542e-08
NZ_CP041607.1\|WP_143604926.1\|11455538_11458142_-\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	9.4916e-51
NZ_CP041607.1\|WP_075032243.1\|11440436_11440922_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	4.93011e-16
NZ_CP041607.1\|WP_143604927.1\|11458450_11458681_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|99777	cd06170, LuxR_C_like, C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.	1.50693e-11
NZ_CP041607.1\|WP_054228623.1\|11463874_11464534_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.7039e-62
NZ_CP041607.1\|WP_143604917.1\|11437222_11438380_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.6824e-28

>NZ_CP041607.1|WP_097281907.1|11447598_11448651_+|serine/threonine-protein-kinase
MGAASGGRELYSGRASGLIGAQIAGYRVEREIGRGGMAVVYCAKDLRLDRTVALKLLAPELARNDTFRRRFTHESLVAAAIDHPHIVPVFEAGETDGVLYIAMRYVSGLDLRALLDRDGPLPVTTALRIAGQVASALDAAHEHDLVHRDVKPGNILVARGTDSDHPEYVYLTDFGLTKKSLSLTGFTTVGEFVGTLDYVAPEQISGRPVDGRCDLYGFACVVYETLAGGPPFQRDDDMALLWAHQYDQPPPLSEQRPGIPPALDGVLAKALAKVPEDRYDSCLEFVAALRAAASGAGAAAAVGKDVHAPTQVVPAVPEAARAPDPVPDPALEPVPDPPRWARPVFGRTPG
>NZ_CP041607.1|WP_143604922.1|11444186_11445524_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MNATPSSTDHRDHTYGTDHAYGTATDRTEPADQEGRTVHLDTAGWGTMPAAVRALVADCASREDRYGPHELEEDLEDVLRTEVHERLGALLGVPAADTAVVTDAAGAFDALVSRLAPGRGERVWTTPYESAARLTALYALRDRTRCTVEVVPLREDGDLDLEWMARHIGDDVALVSVVHVPSGCGIVNPVEEIGQILAPYRCVYAVDASYSAGQLPVDAGRIGCQLLTGDGWRFLRGPYAVGFAFLAPRLRAAFEDAAAHRPLPPNAAVAGLNAALAHHTATATAAADGPAGLAGQGLLPALRAAVEECPGTELIAPGRVQSAILAFRHRDLPAALVRRRLAARGVVVWKTVAQETPLHLPRSGATTALRASLGPDTTPQDIARFGRALREVVREETAGAQRPRPARTLPPAPTPVLASAPAPVPPAGPRPRPSARRHLTLCPTP
>NZ_CP041607.1|WP_143604921.1|11443258_11443852_-|hypothetical-protein
MKNLVARLAVTAATAAVASAVLTAGGISTAADGIGWPKAASTTTTASAQGNIGWPKTTATTAAATDDIGWPKVTVVSANGNIGWPKATATTVSATDDIGWPKVTVVSANGDIGWPKTATTVSATDDIGWPKVTVVSANGDIGWPKTATTVSATDDIGWPKVTVVSANGDIGWPKTTATTVSATDDIGWPVAGGSAAV
>NZ_CP041607.1|WP_143604920.1|11441879_11442548_+|nitroreductase
MDVYEAVTTRRAVRGFTDRPVPREVLERVLSAAAWAPSGSNLQPWHTYVLTGGPLAELKKRADERLATGDPWDEPEYEQYPPALKSPYRERRSAFGEQRYGALGIPREDMEARQRAASANWDCFGAPAALFCYIDRDLGPAQWSDTGMYLQTVMLLLRAEGLHSCPQMAWAKYRKTVAEVLSPPDELILFCGMSIGFEDVTAGYARTGRAPLDETVTFVGDY
>NZ_CP041607.1|WP_143604919.1|11441083_11441734_-|FMN-dependent-NADH-azoreductase
MATLLHIDSSVFPGEASSSRSVTDAFRRAWEEQHPQGTVIYRDLAAAPVPHITADAWSAGYAAPREHTPEQSAAFAARVKLIEELEQADAVLIGAPMYNFSIPSTLKAWLDNVLLLGRTAGETPSAQGTPVIVVASRGGSYAAGTPREDYEFVQNYLEAVLKNTLGLDLDFIVPELTMAPRRPAMSELVPLYEASRKRAFEDATAKARQLGGRLAV
>NZ_CP041607.1|WP_075032243.1|11440436_11440922_+|winged-helix-turn-helix-transcriptional-regulator
MNADVPHRTTPSRVTDRPGDASPFALGLLLRRAHWRAAAVMEEALRPLGIELRHFAVLIVLVDRGPTVQRDLAAATGSDKAGIMRVVDDLERRGLAVRRNVPGDRRVRAVEITPEGVELFDAAHVAAAPLAERLVADLAPGEPEQLTDLLTRFAHPAGGEA
>NZ_CP041607.1|WP_143604918.1|11438638_11440150_-|hypothetical-protein
MSLSGQKPPDRLVPSARTALTALTALPRGAGGGGDGAEHAAPPASGAEPPGTPLQEIVRDLFAEAIGVPRRTVHADSDFFRLGGHPAAAARLLARARRVLGAGLDDRALHEAPTPARFAAAAGERPAAATGPAGALDGTPDGEGSAVLPLRLRGALNAGALQEALGDVGRRHGALRNSRLGSAGTRLRALAARDHLLELTLPADLVDLWSHTPLAAELALAYRARAAGRAPHWEGPVPEAAPRARAGDLAPTVPPGSRPAPADARVGRLALDWDAGLHQRLAHLAATQGATLFMVVHAALAALLTRLGAGPAITVAAPVPARDSAALRRAVGPYGRVLALSVDTSGDPAFTTLLRRVHAADLAAYRTGTAALARPGGIALSVLADSGEAYEAAGLTVRAAPPLLPLRAAALGLILTERHTPAGAPAGIAVTAAYQYDAVGETAAAHLTGQLTALLEAALDTPAAALSRLGGGARPPLAPARTREHAAPSPARRPAPAAVPVAG
>NZ_CP041607.1|WP_143604917.1|11437222_11438380_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKLVTQVKLMPEAEQAAALSVTLHTVNEAANWVSAVAFERGVPREYELRKHTYGELRARGLGAQAAQHIIKKTRDAYTTLKANIKAGNLGRPGSKRRVKAEAKPITFRREAAQPYDDRCLSWQYDAQTVSIWTTAGRIKNVRFACSPDGLKTLREHRQGESDLIERNGVFYLIATCDVPEAEQYEPDHFNGVDLGIANIATTSTGHKAAGRGLNRHRKRQLDLRKKLQAKGTKSAKRLLKKRNRREQRHASNTNHIIAKTIVTEAERTSAGISLEELHGIRQRVRLRKPQRVALHSWAFAQLADFIVYKARRAGVPVVFVDPAYTSQQCCECGHIDKKNRASQALFICRNCGVVAHADRNASHNIARKGEAVWTAGRESRVPATP
>NZ_CP041607.1|WP_143604916.1|11435501_11435963_-|DUF2871-family-protein
MRKSYYAAHVYMILGVVSGLYYREFTKANDFTGDTQLALMHTHLLSLGMMGFLIVLALDKQFALSGTKLFTYFFWFYNVGITITVAMMFVHGTETVLGDHVPEAVPLTAGLGHILLTVGLILLFVLLGKRLNESAGAGPAEPEQEKETAKSPV
>NZ_CP041607.1|WP_143604915.1|11434826_11435432_+|TetR-family-transcriptional-regulator
MTPRERRLREQAQRHRLILTTAREMAESEGWDYVTTRRLADRIEYSQPVLYQHFKNKDAIVHAVALEGFAELAAALRTAREEAGDPQEALGAVARAYADFAEHGPVLYEAMLTLDPGEDTGEDTTGAAGTPAPLADVLAEIRQAVEPVAAGRDSGLLTEVLWSAWHGQAALTRAGRLRPDPARQRLAALTDALLGPAAQPV
>NZ_CP041607.1|WP_143604923.1|11451771_11452227_+|DUF1153-domain-containing-protein
MSRTRWQRPLVLAVASVALATGTACAAQAAPGVTTGTSQMAPADPSHCGHGGEGGKGGEGGKGGAPGQPGEPGKPGQFGCFKFDDLPDKPKSELTGVDKIRIVLTVESGQAKKADVAKKYKISEKEFDTWDKQFRDGDWAALMGLNSLFGS
>NZ_CP041607.1|WP_143604924.1|11452380_11452989_+|hypothetical-protein
MRIRSWKVRLGLTVSTALTAGVAAGALAPAAMAAPMPQNHTAVVAAARQLPADGARPGGGSQFANGQFAGGQFGSGQLGTVKVGDGSVRIGDRVCAGNCNGTVNGSNGGQGGICAGLCNGSANGGTGTAGAPGREGGIGGKGGICAGICGGSANGGTGGTGGAAVGTGDGGRGGKGGTGGICLGLGCESGGMGGRGGTGGAG
>NZ_CP041607.1|WP_143604925.1|11453126_11454362_+|SpoIIE-family-protein-phosphatase
MRERIDYRALFAATPSPYLVLGRDLVIVDVNRAYLLATGRTRAELVGRYLFDAFPDNPADPDADGVRNLSASLHWVLRSKEPDTMAVQKYDIPVAGRPGEFEERWWSPVNTPVLGPDGQVEWIIHRVEDVTEFVLSHPQHAQRISVLGEREAMEAELYARARELQQLNEELRKAHARERQIAVALQEAMLQSPDLAAHQNIAVRYMPAAGSLNVCGDWYDVVDLPGGFAVAVGDVVGHGLEAAAAMGMLRSALSAAVRALHEPARALEVLGLYARSVEGALATTVVKAVIDDQGHRIRYSSAGHLPPVLVHPDGSFDLLDQATDPPLGARPRHVPRPQAELPYTPGDTLVLYTDGLIERRGEDIDVGLRRLTDTLTRHTRLAPERLADMLLARLGVSSGGRDDVALVVVRL
>NZ_CP041607.1|WP_143604926.1|11455538_11458142_-|SpoIIE-family-protein-phosphatase
MERLPTHPGERPHESDASPGPARTAPPTPPPPATAAVDARGIVTEWSEGARQLLGYPPSEVVGQPAARLLADDAGTAGAAALRDAAGRERWSGTVALRHRDGRRLRRELLAHRRTAEGPVTEWLVVSAVTGTPEGQTPGGQTPEGQTPAGTPEGEVPEGEAAGGGTPRSEAYGSGTSGSGRLGEWAFRQAPCVMAVFDADLRLVRANAGMEQVLSLTEDQMRGMRLPEIVPHPVSDETEAKMRRVLEGGGPQQLRAGAGPAGTGANDGWSTSLVPLEDSAGHVRAVCLAAHQRIQEHLARQRMLLLSEASARIGTTADSGRTAQELADIAVPGLADFAAVDLLDAPRHGGAPSPAAPARPLAATRTAVRSVLDDGPTASAAGTAGTAGTKTLYPALSPVARCLAQGHGALYDAADPDLLRWARQDPGAARLLGSTTHSVMVVPMRAHGATLGVALFGRHRHAEPFEADDLWLAEELTAKAAVSIHTARRDSREHTSTMTLQRSLLPQTLPDQGALDIATRYLPAGTRAGVGGDWFDVIPLSGARVALVVGDVVGHGIRASATMGRLRTAVRTLADVDLPPDELLTHLDDLVLHLSADESGTDDTAESAGGIGTTCLYAVYDPVSRRCALARAGHPPPAAVTPDGAVRFLDVPAGPPLGLGGLPFETFETELPEGSLLALYTDGLLAARDHDIDEALDKMFAALARPAKTLDTVCDRVLTAMLTHRPDDDIALLVARTRALHADRVAAWDLASDPAVVARARKHATEQLTAWGLDDAAFITELTVSELVTNAIRYGRPPIQLRLIHEDSTLTCEVFDSSSTAPHMRRARTFDEGGRGLLLVGQLARRWGTRHALTGKTVWAEQSLSPG
>NZ_CP041607.1|WP_143604927.1|11458450_11458681_+|helix-turn-helix-transcriptional-regulator
MSLTLATPHTEAPVPALAPREQETLRHIAAGRTYLQTARHMGLSKHTVDAYLRRIRAKLNINSTAELTRLAISMGL
>NZ_CP041607.1|WP_143605864.1|11459588_11460467_-|NAD-dependent-epimerase
MIVGRGAAASKTALLLAEDGERVRMISRTGGGPDHPLIDKVTADATDTDRLTELAEGADTLFTTAAPPYHLWPEQFPILSGSLLSAVKRTGAAYVMLGNLYAYGPASGPITPDFPLAATGPKGRTRARAWEEAAASGVKVTEVRAAQFYGAGAFSVFSLMVQRQVLEGKLVLVPQELDVPHSYSAIGDTARTLVAASRNEQAYGRAWHVPTSTLSVRELAVRLAELAGAPEPRMEEMSERDLTLLAFTEPFWAEMHEVLTKPGHPFVIDYSETEKILGVSATPANDVLREVI
>NZ_CP041607.1|WP_143604928.1|11460550_11461492_+|helix-turn-helix-domain-containing-protein
MHRVAAVIVPPVLSFDVSIPLMVFNSVPHYDVRVCTARPGPMPTVSGPDIVVPDGLDAVEGADTVIAVGSGGEQAPTEALDALRKAAATGARIASLCTGAFVLAQAGLLDGLRATTHWGLAGDLATRFPSIDVQPDLLFVEDGGIFTSAGAAAAIDLCLHLVRIDYGAAVANTAARLAVVPPVRPGGQSQFIETPLPPERGTSLAPTRAWALEHLDRPLTLADLAGHAKMSVRTLSRRFHAETGLSPLQWLLHRRIDRARELLEMTELPMDQVAQKSGLGSADSLRKHMVGRVGLTPTAYRASFNRAPTGASR
>NZ_CP041607.1|WP_143604929.1|11461751_11463632_+|glycoside-hydrolase-family-15-protein
MAEATPEAGAKDRDRTYTGPRGTGTPGYLPIAEHGLIGDLRSAALVGTNGTIDWYCCPRFDAPSVFASILDAERGGSFELAPDVPTRTKQFYFPDTNVLITRFFADDGVGEIQDFMPVVDESREADRHRLIRRVVCVRGALPFRARVAPRFEYGTAPHTVHAEAGQAVFASASLRLALTSTVPIEVDGPDVWALFKLHEGETAVFTIDKIGGDVAPRFCAAAEAEREFNATVRYWRHWLSQSRYRGRWREMVHRSALTLKLLTYAPTGAIVAAPTTSLPEQIGGERNWDYRYVWIRDAAFCVYAMLRLGFTDEAEAFMGFVTEHVQRAPDGPTGPTGPLQIMYGIDGCRDLPERELPHLEGYRGSAPVRVGNAAVDQLQLDIYGALVDSLYLYDKWGKPISSAHWDSISELVDWVCDHWDQPDEGVWETRGGRKTFLYSRLMCWVAIERAMRLARHRGLPADMVRWGAVRDTIYRRIMSHGWSAERHAFTQYEDSDILDASLLMMPLAKFIAPTDPKWLATLDALGEDLVSDSLVYRYDPQASPDGLQGEEGTFSICSFWYVEALTRAGRLDEARLAFEKMLTYANHLGLYAEEIGHTGEQRGNFPQAFTHLALISAAFNLDRMLG
>NZ_CP041607.1|WP_054228623.1|11463874_11464534_-|response-regulator-transcription-factor
MTRILIVDDQDEIRAGIKAMLRLDPSLVVAGDLSDGLQVVPFLRDHPVDLVLMDIRMPGIDGVEATRRIRKEHPPEKMRVIVLTTFDQDDIVLAALRAGANGFLSKTVSPAELVAGITEVVGGGGALSAAATAALIGHMTDSPPPVIDQELLRRFDALTPRERDVVVLVASGLGNDEIAAQMSVSPFTVKTHAVRAMTKVGARDRAQLVSFVFRAGLYP
>NZ_CP041607.1|WP_095849905.1|11464588_11464912_-|hypothetical-protein
MNPPPAEAGGFLAQAACGSSGPTGLTPSTPAGSEPARFGTTSKGVAVLAWLSLSTVCALGSRNAHRPRYPIAWTVFRPGGETPFPALLRRSPIPSRPEGRGILGGTR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	376197-376227	5	0.839
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP035420	Leisingera sp. NJS204 plasmid unnamed3, complete sequence	132843-132875	5	0.848
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	376196-376227	6	0.812
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	387807-387837	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP034352	Streptomyces sp. W1SF4 plasmid p2, complete sequence	30815-30845	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP049734	Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence	247493-247523	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	CP049734	Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence	36225-36255	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	277269-277299	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP054030	Rhizobium sp. JKLM19E plasmid pPR19E03	108707-108737	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	200849-200879	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP054035	Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence	202107-202137	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1006785-1006815	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP054024	Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence	288799-288829	6	0.806
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	185161-185191	6	0.806
NZ_CP041607_3	3.2\|1414076\|33\|NZ_CP041607\|CRT	1414076-1414108	33	NZ_CP041652	Streptomyces sp. RLB1-9 plasmid pRLB1-9.2, complete sequence	73497-73529	6	0.818
NZ_CP041607_1	1.1\|1022776\|38\|NZ_CP041607\|CRISPRCasFinder	1022776-1022813	38	NZ_CP041605	Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence	41245-41282	7	0.816
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	387807-387838	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP049734	Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence	247493-247524	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	CP049734	Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence	36225-36256	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	1148386-1148417	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP030762	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence	277269-277300	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP054024	Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence	288798-288829	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP054030	Rhizobium sp. JKLM19E plasmid pPR19E03	108707-108738	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	200849-200880	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	1088319-1088350	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP054035	Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence	202107-202138	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1006785-1006816	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	185160-185191	7	0.781
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	685455-685486	7	0.781
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP022366	Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence	175990-176020	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	461479-461509	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	614199-614229	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP049160	Caballeronia sp. SBC1 plasmid pSBC1_4, complete sequence	48221-48251	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	106871-106901	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	266716-266746	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1591618-1591648	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	1148386-1148416	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	1088320-1088350	7	0.774
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	685456-685486	7	0.774
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	283205-283237	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	114014-114046	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	608566-608598	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	596917-596949	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	494124-494156	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	563496-563528	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	494124-494156	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	497998-498030	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	497988-498020	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	494136-494168	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	494156-494188	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	494109-494141	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	608613-608645	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	608613-608645	7	0.788
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	608604-608636	7	0.788
NZ_CP041607_21	21.1\|10101569\|30\|NZ_CP041607\|CRISPRCasFinder	10101569-10101598	30	NZ_CP029211	Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence	233204-233233	7	0.767
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	647205-647236	7	0.781
NZ_CP041607_2	2.1\|1182236\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182236-1182267	32	NC_009469	Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence	2824-2855	8	0.75
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP049160	Caballeronia sp. SBC1 plasmid pSBC1_4, complete sequence	48220-48251	8	0.75
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1591618-1591649	8	0.75
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP042268	Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence	19151-19182	8	0.75
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP042268	Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence	19151-19181	8	0.742
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	29274-29304	8	0.742
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NC_006824	Aromatoleum aromaticum EbN1 plasmid 2, complete sequence	149605-149637	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1056228-1056260	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NC_014642	Achromobacter xylosoxidans A8 plasmid pA82, complete sequence	62401-62433	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1121064-1121096	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3436641-3436673	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP026974	Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence	236516-236548	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1084651-1084683	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	186868-186900	8	0.758
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP026539	Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence	89954-89986	8	0.758
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	77748-77779	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1664535-1664566	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1621380-1621411	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	77568-77599	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	48739-48770	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	1319977-1320008	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	77857-77888	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	77746-77777	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	1226887-1226918	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	343836-343867	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	407773-407804	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	329851-329882	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	1347665-1347696	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	893276-893307	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	866539-866570	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	937080-937111	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	231057-231088	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	80468-80499	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	190498-190529	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	1555142-1555173	8	0.75
NZ_CP041607_22	22.2\|11130863\|32\|NZ_CP041607\|CRISPRCasFinder	11130863-11130894	32	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1664550-1664581	8	0.75
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MH593831	Podoviridae sp. isolate ctdb7, complete genome	34371-34402	8	0.75
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	JN699011	Mycobacterium phage Stinger, complete genome	26862-26893	8	0.75
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	749225-749256	8	0.75
NZ_CP041607_2	2.1\|1182236\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182236-1182267	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	718143-718174	9	0.719
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	29273-29304	9	0.719
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	185793-185824	9	0.719
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	185793-185823	9	0.71
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	1006335-1006367	9	0.727
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2371973-2372005	9	0.727
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP039902	Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence	68619-68651	9	0.727
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP039893	Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence	33418-33450	9	0.727
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	645459-645491	9	0.727
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_KY000025	Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence	172421-172453	9	0.727
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_KY000029	Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence	172421-172453	9	0.727
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MN369759	Mycobacterium phage Mithril, complete genome	28303-28334	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MK524486	Mycobacterium phage Waleliano, complete genome	28288-28319	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MN234171	Mycobacterium phage Magpie, complete genome	28128-28159	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MH513970	Mycobacterium phage Hangman, complete genome	28285-28316	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MT639648	Mycobacterium phage Heath, complete genome	27886-27917	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NC_042035	Mycobacterium phage Zemanar, complete sequence	28288-28319	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NC_008195	Mycobacterium phage Cooper, complete genome	27475-27506	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NC_028968	Mycobacterium phage BrownCNA, complete genome	28554-28585	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1081964-1081995	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NZ_CP013071	Sphingobium indicum B90A plasmid pSRL1, complete sequence	77383-77414	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	409730-409761	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	MH834619	Arthrobacter phage Maureen, complete genome	36155-36186	9	0.719
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NC_048115	Arthrobacter phage Liebe, complete genome	36155-36186	9	0.719
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	603163-603193	10	0.677
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	337789-337819	10	0.677
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NC_011366	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence	140428-140458	10	0.677
NZ_CP041607_2	2.5\|1182359\|31\|NZ_CP041607\|PILER-CR	1182359-1182389	31	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	104395-104425	10	0.677
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	699286-699318	10	0.697
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	696799-696831	10	0.697
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	694960-694992	10	0.697
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	349318-349350	10	0.697
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_LR134445	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 3, complete sequence	54282-54314	10	0.697
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	356694-356726	10	0.697
NZ_CP041607_3	3.1\|1414015\|33\|NZ_CP041607\|CRT	1414015-1414047	33	NZ_CP015597	Mycobacterium sp. YC-RL4 plasmid pMYC1, complete sequence	90231-90263	10	0.697
NZ_CP041607_3	3.3\|1414137\|33\|NZ_CP041607\|CRT	1414137-1414169	33	NZ_CP041606	Streptomyces sp. S1D4-14 plasmid pS1D4-14.2, complete sequence	8876-8908	10	0.697
NZ_CP041607_3	3.4\|1414198\|34\|NZ_CP041607\|CRT	1414198-1414231	34	KC292021	Halovirus HRTV-7, complete genome	18342-18375	10	0.706
NZ_CP041607_16	16.1\|7960426\|37\|NZ_CP041607\|CRISPRCasFinder	7960426-7960462	37	NZ_CP005190	Sphingobium sp. MI1205 plasmid pMI1, complete sequence	238525-238561	10	0.73
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	KF279411	Mycobacterium phage Adawi, complete genome	26973-27004	10	0.688
NZ_CP041607_23	23.2\|11451430\|39\|NZ_CP041607\|PILER-CR	11451430-11451468	39	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1004831-1004869	10	0.744
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	337789-337820	11	0.656
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NC_011366	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence	140427-140458	11	0.656
NZ_CP041607_2	2.3\|1182358\|32\|NZ_CP041607\|CRISPRCasFinder,CRT	1182358-1182389	32	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	104394-104425	11	0.656
NZ_CP041607_3	3.6\|1414321\|33\|NZ_CP041607\|CRT	1414321-1414353	33	MN855955	Bacteriophage sp. isolate 57, complete genome	27638-27670	11	0.667
NZ_CP041607_3	3.6\|1414321\|33\|NZ_CP041607\|CRT	1414321-1414353	33	MN856062	Bacteriophage sp. isolate 351, complete genome	2481-2513	11	0.667
NZ_CP041607_22	22.3\|11130924\|32\|NZ_CP041607\|CRISPRCasFinder	11130924-11130955	32	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	268571-268602	11	0.656
NZ_CP041607_23	23.2\|11451430\|39\|NZ_CP041607\|PILER-CR	11451430-11451468	39	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	685570-685608	11	0.718

1. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.839

agcaccgccgccgacccgtccg-cgtgcggca	CRISPR spacer
agcaccgccgccgccccggccgccgcccggc-	Protospacer
************* **** *** **. ****

2. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP035420 (Leisingera sp. NJS204 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.848

caacgccgccgtcgccgacatcgac-gtgatggc	CRISPR spacer
caacgccgccctcgccgatatcgacaatgacgg-	Protospacer
********** *******.****** .***.**

3. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.812

agcaccgccgccgacccgtccg-cgtgcggcac	CRISPR spacer
agcaccgccgccgccccggccgccgcccggct-	Protospacer
************* **** *** **. ****

4. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccatcccgtccgcgtccccga	Protospacer
************. *********** *   *

5. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP034352 (Streptomyces sp. W1SF4 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccg-ccgccgacccgtccgcgtgcggca	CRISPR spacer
-acgccgcccgccgaccagtccgcgtgcggtg	Protospacer
 .*.*** ********* ************..

6. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP049734 (Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccgccccctccgcccccgcca	Protospacer
************* *** ***** . ** **

7. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to CP049734 (Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccgccccctccgcccccgcca	Protospacer
************* *** ***** . ** **

8. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccgccccctccgccgccgcca	Protospacer
************* *** *****   ** **

9. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP054030 (Rhizobium sp. JKLM19E plasmid pPR19E03) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccgccccctccgcccccgcca	Protospacer
************* *** ***** . ** **

10. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtg-cggca	CRISPR spacer
tcgaccgtcgccgacccgtcctcgtgacggc-	Protospacer
   ****.************* **** ****

11. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP054035 (Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccgccccctccgcccccgcca	Protospacer
************* *** ***** . ** **

12. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgt-gcggca	CRISPR spacer
tcgaccgtcgccgacccgtcctcgtggcggc-	Protospacer
   ****.************* *** *****

13. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP054024 (Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccgccgccccctccgcccccgcca	Protospacer
************* *** ***** . ** **

14. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.806

agcaccgccgccgacccgtccgcgtg-cggca	CRISPR spacer
tcgaccgtcgccgacccgtcctcgtgacggc-	Protospacer
   ****.************* **** ****

15. spacer 3.2|1414076|33|NZ_CP041607|CRT matches to NZ_CP041652 (Streptomyces sp. RLB1-9 plasmid pRLB1-9.2, complete sequence) position: , mismatch: 6, identity: 0.818

cggaatcgggctgagtcgaatgctgggaagcgg	CRISPR spacer
tttggtagggctgagtcgaatgctgggaagcgg	Protospacer
.  ..* **************************

16. spacer 1.1|1022776|38|NZ_CP041607|CRISPRCasFinder matches to NZ_CP041605 (Streptomyces sp. S1D4-14 plasmid pS1D4-14.1, complete sequence) position: , mismatch: 7, identity: 0.816

ttcgccgtggtcgaaattcacggcgaaggtgctttccc	CRISPR spacer
gtcgccgtggtcgaaattcacggcgaaggttcggccgg	Protospacer
 ***************************** *  .*

17. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccatcccgtccgcgtccccgag	Protospacer
************. *********** *   *

18. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP049734 (Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccgccccctccgcccccgccag	Protospacer
************* *** ***** . ** **

19. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to CP049734 (Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccgccccctccgcccccgccag	Protospacer
************* *** ***** . ** **

20. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccg----cgtgcggcac	CRISPR spacer
agcagcgccgccgacgcgtccgctgccttgcg----	Protospacer
**** ********** ******    * ****

21. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP030762 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccgccccctccgccgccgccag	Protospacer
************* *** *****   ** **

22. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP054024 (Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccgccccctccgcccccgccag	Protospacer
************* *** ***** . ** **

23. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP054030 (Rhizobium sp. JKLM19E plasmid pPR19E03) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccgccccctccgcccccgccag	Protospacer
************* *** ***** . ** **

24. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtg-cggcac	CRISPR spacer
tcgaccgtcgccgacccgtcctcgtgacggcg-	Protospacer
   ****.************* **** ****.

25. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccg----cgtgcggcac	CRISPR spacer
agcagcgccgccgacgcgtccgctgccttgcg----	Protospacer
**** ********** ******    * ****

26. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP054035 (Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccgccgccccctccgcccccgccag	Protospacer
************* *** ***** . ** **

27. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgt-gcggcac	CRISPR spacer
tcgaccgtcgccgacccgtcctcgtggcggct-	Protospacer
   ****.************* *** *****

28. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccgcgtg-cggcac	CRISPR spacer
tcgaccgtcgccgacccgtcctcgtgacggcg-	Protospacer
   ****.************* **** ****.

29. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 7, identity: 0.781

agcaccgccgccgacccgtccg----cgtgcggcac	CRISPR spacer
agcagcgccgccgacgcgtccgctgccttgcg----	Protospacer
**** ********** ******    * ****

30. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP022366 (Azospirillum sp. TSH58 plasmid TSH58_p04, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgt--gcggca	CRISPR spacer
tcgaccgccgccgacccgtccgggttgccgg--	Protospacer
   ******************* **   ***

31. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgt--gcggca	CRISPR spacer
tcgaccgccgccgacccgtccgggttgccgg--	Protospacer
   ******************* **   ***

32. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgt--gcggca	CRISPR spacer
tcgaccgccgccgacccgtccgggttgccgg--	Protospacer
   ******************* **   ***

33. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP049160 (Caballeronia sp. SBC1 plasmid pSBC1_4, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agtgatgccgcggacccgtgcgcgtgcggcc	Protospacer
**.. .***** ******* **********

34. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgt--gcggca	CRISPR spacer
tcgaccgccgccgacccgtccgggttgccgg--	Protospacer
   ******************* **   ***

35. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgt--gcggca	CRISPR spacer
tcgaccgccgccgacccgtccgggttgccgg--	Protospacer
   ******************* **   ***

36. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
agcaccgccagcgacccgtccgccgtcagga	Protospacer
*********. ************   *.* *

37. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccg----cgtgcggca	CRISPR spacer
agcagcgccgccgacgcgtccgctgccttgc----	Protospacer
**** ********** ******    * ***

38. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccg----cgtgcggca	CRISPR spacer
agcagcgccgccgacgcgtccgctgccttgc----	Protospacer
**** ********** ******    * ***

39. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 7, identity: 0.774

agcaccgccgccgacccgtccg----cgtgcggca	CRISPR spacer
agcagcgccgccgacgcgtccgctgccttgc----	Protospacer
**** ********** ******    * ***

40. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
caacgccgccatcgccgacctcgacctcaacgg	Protospacer
**********.******** ***** * *  *

41. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc-	CRISPR spacer
caccgtcgccgtcgccgacatcgac-tgggaacg	Protospacer
** **.******************* **. ..*

42. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

43. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

44. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

45. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

46. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

47. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

48. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

49. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

50. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

51. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

52. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

53. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

54. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgccgccgtcgccggcatcgccgtccaggc	Protospacer
*..**************.***** ***   ***

55. spacer 21.1|10101569|30|NZ_CP041607|CRISPRCasFinder matches to NZ_CP029211 (Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence) position: , mismatch: 7, identity: 0.767

acgcagcgacctcgtggcacggt-gtcagca	CRISPR spacer
ccgcagcgacctcgtggcccggcggattgc-	Protospacer
 ***************** ***. * . **

56. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 7, identity: 0.781

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tccagcatgccccagcagggaaagttgaaggc	Protospacer
.**.. ** *.******************* *

57. spacer 2.1|1182236|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NC_009469 (Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence) position: , mismatch: 8, identity: 0.75

gccaagccatcgacggggaaggggagtcggct	CRISPR spacer
gccatgccagcgacggggaagggccggagcat	Protospacer
**** **** *************  *  *  *

58. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP049160 (Caballeronia sp. SBC1 plasmid pSBC1_4, complete sequence) position: , mismatch: 8, identity: 0.75

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agtgatgccgcggacccgtgcgcgtgcggcca	Protospacer
**.. .***** ******* **********

59. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.75

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
agcaccgccagcgacccgtccgccgtcaggaa	Protospacer
*********. ************   *.* *

60. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP042268 (Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence) position: , mismatch: 8, identity: 0.75

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
cgcaccgccgccgacgcggccgcgcggttcgc	Protospacer
 ************** ** *****.*   *.*

61. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP042268 (Pseudomonas aeruginosa strain HOU1 plasmid pHOU1-1, complete sequence) position: , mismatch: 8, identity: 0.742

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
cgcaccgccgccgacgcggccgcgcggttcg	Protospacer
 ************** ** *****.*   *.

62. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 8, identity: 0.742

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
ctcgccgccgccgacccggccgggtgccgac	Protospacer
  *.************** *** **** *

63. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NC_006824 (Aromatoleum aromaticum EbN1 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
gcacgccgccttcgccgacatcgacggccttgt	Protospacer
  ******** ***************   * *.

64. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
gaacgccgccgtcgccgccagcgacgccgccgc	Protospacer
 **************** ** *****. .. **

65. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NC_014642 (Achromobacter xylosoxidans A8 plasmid pA82, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgtcggcgtcgccgacatcgacgtggttca	Protospacer
*..**.** *******************.*

66. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
tgacgccgccgtcgccgccatcgccgtcacgct	Protospacer
..*************** ***** *** *.* .

67. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cgtcgccgccgacgcggacatcgacgtcgcagc	Protospacer
*. ******** *** *********** ...**

68. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP026974 (Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cggcgtcggcgtcgccgacatcgacgtggttca	Protospacer
*..**.** *******************.*

69. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
tgacgccgccgtcgccgccatcgccgtcacgct	Protospacer
..*************** ***** *** *.* .

70. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
gaacgccgccgtggccgacaccgaccggccgga	Protospacer
 *********** *******.****  * .**

71. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP026539 (Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence) position: , mismatch: 8, identity: 0.758

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cgacgccgccgccgccgacatcgccgcccggga	Protospacer
*.*********.*********** **.   **

72. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

73. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

74. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

75. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

76. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

77. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

78. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

79. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

80. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

81. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

82. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

83. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

84. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

85. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

86. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

87. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

88. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

89. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

90. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

91. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

92. spacer 22.2|11130863|32|NZ_CP041607|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

cccgagatcctccagcagggaaagttgaagcc	CRISPR spacer
tcgagcatgccccagcagggaaagttgaaggc	Protospacer
.* .. ** *.******************* *

93. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MH593831 (Podoviridae sp. isolate ctdb7, complete genome) position: , mismatch: 8, identity: 0.75

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
tcgatgacctgggcctgggcctcgatcttctg	Protospacer
   .** ********************  * *

94. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to JN699011 (Mycobacterium phage Stinger, complete genome) position: , mismatch: 8, identity: 0.75

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatgcg	Protospacer
 .******* ** **************.   *

95. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
gagatgccgagggcctgggcctcgatcatcgc	Protospacer
** .****  *****************. *.

96. spacer 2.1|1182236|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 9, identity: 0.719

gccaagccatcgacggggaaggggagtcggct	CRISPR spacer
gcgtgaccatcgacgaggaaggggagacgcgg	Protospacer
**  ..*********.********** **

97. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 9, identity: 0.719

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
ctcgccgccgccgacccggccgggtgccgacg	Protospacer
  *.************** *** **** *

98. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 9, identity: 0.719

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
gcctgcgccgcggacccgtccgcgggcgtgcc	Protospacer
. *  ****** ************ ***   *

99. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 9, identity: 0.71

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
gcctgcgccgcggacccgtccgcgggcgtgc	Protospacer
. *  ****** ************ ***

100. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
attcgccgccgacgccgtcatcgacgtaacccc	Protospacer
   ******** ***** *********.*.  *

101. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
attcgccgccgacgccgtcatcgacgtaacccc	Protospacer
   ******** ***** *********.*.  *

102. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP039902 (Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc-	CRISPR spacer
taacggcgccgtcgccgacctcgac-catcgact	Protospacer
.**** ************* ***** .. .*.*

103. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP039893 (Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc-	CRISPR spacer
taacggcgccgtcgccgacctcgac-catcgact	Protospacer
.**** ************* ***** .. .*.*

104. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
gacggccgccggcgccgacatcgtcgtggcgca	Protospacer
 *  ******* *********** ****..*

105. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_KY000025 (Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc-	CRISPR spacer
taacggcgccgtcgccgacctcgac-catcgact	Protospacer
.**** ************* ***** .. .*.*

106. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_KY000029 (Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence) position: , mismatch: 9, identity: 0.727

caacgccgccgtcgccgacatcgacgtgatggc-	CRISPR spacer
taacggcgccgtcgccgacctcgac-catcgact	Protospacer
.**** ************* ***** .. .*.*

107. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MN369759 (Mycobacterium phage Mithril, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatggc	Protospacer
 .******* ** **************.  .

108. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MK524486 (Mycobacterium phage Waleliano, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatggc	Protospacer
 .******* ** **************.  .

109. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MN234171 (Mycobacterium phage Magpie, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatgga	Protospacer
 .******* ** **************.  ..

110. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MH513970 (Mycobacterium phage Hangman, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatggc	Protospacer
 .******* ** **************.  .

111. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MT639648 (Mycobacterium phage Heath, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatgga	Protospacer
 .******* ** **************.  ..

112. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NC_042035 (Mycobacterium phage Zemanar, complete sequence) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatgga	Protospacer
 .******* ** **************.  ..

113. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NC_008195 (Mycobacterium phage Cooper, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatgga	Protospacer
 .******* ** **************.  ..

114. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NC_028968 (Mycobacterium phage BrownCNA, complete genome) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgcgtgcccaggccctgggcctcgatcatggc	Protospacer
 .******* ** **************.  .

115. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
ttcaggccccgggcctgggcctcgttcgcgac	Protospacer
  *. ****.************** ***  *

116. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP013071 (Sphingobium indicum B90A plasmid pSRL1, complete sequence) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
accgcgccctgggcctgggcatcgacatgcgg	Protospacer
. **.*************** ****.  .*.*

117. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
accgtgccctgggcctgagcgtcgaaggcgcg	Protospacer
. ***************.** ****  *   *

118. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to MH834619 (Arthrobacter phage Maureen, complete genome) position: , mismatch: 9, identity: 0.719

gacgt-gccctgggcctgggcctcgatcgacag	CRISPR spacer
-ctgtagcccgggacctgggcctcgatcgcggc	Protospacer
  .** **** **.***************  .

119. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NC_048115 (Arthrobacter phage Liebe, complete genome) position: , mismatch: 9, identity: 0.719

gacgt-gccctgggcctgggcctcgatcgacag	CRISPR spacer
-ctgtagcccgggacctgggcctcgatcgcggc	Protospacer
  .** **** **.***************  .

120. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.677

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
tcgaccgccgccgacccgtccgggtttccgg	Protospacer
   ******************* ** .   .

121. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 10, identity: 0.677

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
gatgccgccgccgatccggccgcgtgccttg	Protospacer
....**********.*** ********  ..

122. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NC_011366 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence) position: , mismatch: 10, identity: 0.677

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
gatgccgccgccgatccgtccccgtgccttc	Protospacer
....**********.****** *****  .

123. spacer 2.5|1182359|31|NZ_CP041607|PILER-CR matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 10, identity: 0.677

agcaccgccgccgacccgtccgcgtgcggca	CRISPR spacer
gatgccgccgccgatccgtccccgtgccttg	Protospacer
....**********.****** *****  ..

124. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
caacgccgccgtcgcctacagcgaatccttcct	Protospacer
**************** *** ***  .  *  .

125. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
caacgccgccgtcgcctacagcgaatccttcct	Protospacer
**************** *** ***  .  *  .

126. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
caacgccgccgtcgcctacagcgaatccttcct	Protospacer
**************** *** ***  .  *  .

127. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
caacgccgccgtcgcctacagcgaatccttcct	Protospacer
**************** *** ***  .  *  .

128. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_LR134445 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 3, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
cgccgctgccgtcgccgacctcgacgttccact	Protospacer
*. ***.************ *******  .. .

129. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
caacgccgccgtcgcctacagcgaatccttcct	Protospacer
**************** *** ***  .  *  .

130. spacer 3.1|1414015|33|NZ_CP041607|CRT matches to NZ_CP015597 (Mycobacterium sp. YC-RL4 plasmid pMYC1, complete sequence) position: , mismatch: 10, identity: 0.697

caacgccgccgtcgccgacatcgacgtgatggc	CRISPR spacer
gctcgacgccgacgccgacatcgacgtcgacac	Protospacer
   ** ***** *************** .  .*

131. spacer 3.3|1414137|33|NZ_CP041607|CRT matches to NZ_CP041606 (Streptomyces sp. S1D4-14 plasmid pS1D4-14.2, complete sequence) position: , mismatch: 10, identity: 0.697

cgcatcgcgcaggacgtgaaggatcaggtccgg	CRISPR spacer
aaggacgcgcaggacgtgaaggaccagatcgct	Protospacer
 . . ******************.***.**

132. spacer 3.4|1414198|34|NZ_CP041607|CRT matches to KC292021 (Halovirus HRTV-7, complete genome) position: , mismatch: 10, identity: 0.706

ccgaagcttcaactcgcgcggctttgctgccgcc	CRISPR spacer
ccgaagcgtcaactcccgcggcttaatctcgaac	Protospacer
******* ******* ******** ... * . *

133. spacer 16.1|7960426|37|NZ_CP041607|CRISPRCasFinder matches to NZ_CP005190 (Sphingobium sp. MI1205 plasmid pMI1, complete sequence) position: , mismatch: 10, identity: 0.73

agtgcctcaccggcccggattcgttcggctgcggggt	CRISPR spacer
cctgccccaccggcccggattcgctcggccagtgtgc	Protospacer
  ****.****************.*****..  * *.

134. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to KF279411 (Mycobacterium phage Adawi, complete genome) position: , mismatch: 10, identity: 0.688

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
cgtgtgcccaggccctgggcctcgatcatgga	Protospacer
 ..****** ** **************.  ..

135. spacer 23.2|11451430|39|NZ_CP041607|PILER-CR matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.744

accggcctgttcggcggcagcgccggctccggcggctcc	CRISPR spacer
tcgaacgggttcggcggcgtcgccggctccggcggcggc	Protospacer
 * ..*  **********. ****************  *

136. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 11, identity: 0.656

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
gatgccgccgccgatccggccgcgtgccttgg	Protospacer
....**********.*** ********  ..

137. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NC_011366 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence) position: , mismatch: 11, identity: 0.656

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
gatgccgccgccgatccgtccccgtgccttcg	Protospacer
....**********.****** *****  .

138. spacer 2.3|1182358|32|NZ_CP041607|CRISPRCasFinder,CRT matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 11, identity: 0.656

agcaccgccgccgacccgtccgcgtgcggcac	CRISPR spacer
gatgccgccgccgatccgtccccgtgccttgg	Protospacer
....**********.****** *****  ..

139. spacer 3.6|1414321|33|NZ_CP041607|CRT matches to MN855955 (Bacteriophage sp. isolate 57, complete genome) position: , mismatch: 11, identity: 0.667

cggcgcgtggcaggcccgctcatcgcgtccctc	CRISPR spacer
attggcggggcaggcccgctcttcgcgttgggt	Protospacer
    *** ************* ******.   .

140. spacer 3.6|1414321|33|NZ_CP041607|CRT matches to MN856062 (Bacteriophage sp. isolate 351, complete genome) position: , mismatch: 11, identity: 0.667

cggcgcgtggcaggcccgctcatcgcgtccctc	CRISPR spacer
atcggcggggcaggcccgctcttcgcgttgggt	Protospacer
    *** ************* ******.   .

141. spacer 22.3|11130924|32|NZ_CP041607|CRISPRCasFinder matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 11, identity: 0.656

gacgtgccctgggcctgggcctcgatcgacag	CRISPR spacer
agtaacgactgggcctgggacacgatcgacaa	Protospacer
....    *********** * *********.

142. spacer 23.2|11451430|39|NZ_CP041607|PILER-CR matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 11, identity: 0.718

accggcctgttcggcggcagcgccggctccggcggctcc	CRISPR spacer
gcccagtccatcggcggcggcggcggctccggcggctcg	Protospacer
.** . ..  ********.*** ***************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

9976 : 72430

Mycobacterium_phage(33.33%)

transposase,protease,integrase

attL 9533:9571|attR 26156:26194

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
9533:9571	attL	NA	NA	NA	NA
WP_143599454.1\|9976_11131_-\|integrase	tyrosine-type recombinase/integrase	A0A1D8EW73	Mycobacterium_phage	2.5e-21	34.8
WP_143599455.1\|11740_11944_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.7e-21	75.8
WP_143599456.1\|13648_14008_-	hypothetical protein	NA	NA	NA	NA
WP_143605090.1\|14720_15035_-	PH domain-containing protein	NA	NA	NA	NA
WP_143599457.1\|15429_15774_+	hypothetical protein	NA	NA	NA	NA
WP_143599458.1\|15996_17181_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143599459.1\|17277_18088_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_143599460.1\|18089_18395_-	hypothetical protein	NA	NA	NA	NA
WP_143599461.1\|18500_19046_+	hypothetical protein	NA	NA	NA	NA
WP_143599462.1\|19483_19993_+	hypothetical protein	NA	NA	NA	NA
WP_143599463.1\|20337_21012_+	hypothetical protein	NA	NA	NA	NA
WP_097289593.1\|21369_21903_+	NUDIX hydrolase	NA	NA	NA	NA
WP_143599464.1\|24056_24800_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_143599465.1\|24824_25403_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_054237353.1\|25686_26025_+	hypothetical protein	NA	NA	NA	NA
WP_143599466.1\|26209_26392_-	hypothetical protein	NA	NA	NA	NA
26156:26194	attR	NA	NA	NA	NA
WP_054237351.1\|26457_26916_-	hypothetical protein	NA	NA	NA	NA
WP_143599467.1\|27508_29167_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_097289597.1\|30051_30879_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_097289598.1\|31666_32023_-	hypothetical protein	NA	NA	NA	NA
WP_143599468.1\|32478_32871_+	hypothetical protein	NA	NA	NA	NA
WP_143599469.1\|32790_33801_-	Ku protein	NA	NA	NA	NA
WP_143599470.1\|34315_34924_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_143599471.1\|35421_36300_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_143599472.1\|36348_37617_+	two-component sensor histidine kinase	NA	NA	NA	NA
WP_143599473.1\|37621_38314_+	response regulator	NA	NA	NA	NA
WP_143599474.1\|38475_38850_-	hypothetical protein	NA	NA	NA	NA
WP_143599475.1\|39141_39345_-	hypothetical protein	NA	NA	NA	NA
WP_143599476.1\|39572_41054_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_143599477.1\|41066_41543_-	hypothetical protein	NA	NA	NA	NA
WP_143599478.1\|42029_43310_-	GNAT family N-acetyltransferase	R4TQL5	Phaeocystis_globosa_virus	2.1e-21	33.3
WP_143599479.1\|43546_44872_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_143599480.1\|48324_48858_+	CbrC family protein	NA	NA	NA	NA
WP_143599481.1\|48936_49473_-	DUF4240 domain-containing protein	NA	NA	NA	NA
WP_143599482.1\|49530_50601_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_143599483.1\|50712_51243_-	carbonic anhydrase	NA	NA	NA	NA
WP_143599484.1\|51647_52037_-	hypothetical protein	NA	NA	NA	NA
WP_054237343.1\|52726_53413_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_143599485.1\|53580_53994_+	DUF2399 domain-containing protein	NA	NA	NA	NA
WP_143599486.1\|54595_55066_+	hypothetical protein	NA	NA	NA	NA
WP_143599487.1\|55151_55424_+	hypothetical protein	NA	NA	NA	NA
WP_143599488.1\|57298_58195_-	META domain-containing protein	NA	NA	NA	NA
WP_143599489.1\|59506_60112_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_054228298.1\|60110_60401_+	hypothetical protein	NA	NA	NA	NA
WP_143599490.1\|60655_60859_-	hypothetical protein	NA	NA	NA	NA
WP_143599491.1\|60857_62321_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143599492.1\|62324_66140_+	hypothetical protein	NA	NA	NA	NA
WP_143605091.1\|66614_67211_+	DUF2461 family protein	NA	NA	NA	NA
WP_143599493.1\|68029_68290_+	hypothetical protein	NA	NA	NA	NA
WP_143599494.1\|69522_69843_+	MafI family immunity protein	NA	NA	NA	NA
WP_143599495.1\|69869_70442_-	hypothetical protein	NA	NA	NA	NA
WP_143599496.1\|70717_72430_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

108340 : 177587

Virus_Rctr71(20.0%)

transposase,protease,integrase

attL 123241:123257|attR 159619:159635

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143599523.1\|108340_109132_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_143599524.1\|109088_109634_-	hypothetical protein	NA	NA	NA	NA
WP_143605096.1\|110097_111120_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_143599525.1\|111374_112814_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_143605097.1\|114258_114675_+	hypothetical protein	NA	NA	NA	NA
WP_143599526.1\|114798_115053_-	hypothetical protein	NA	NA	NA	NA
WP_143605098.1\|115049_115355_-	hypothetical protein	NA	NA	NA	NA
WP_143599527.1\|115474_115816_-	hypothetical protein	NA	NA	NA	NA
WP_143599528.1\|115947_116472_+	ATP-binding protein	NA	NA	NA	NA
WP_143599529.1\|116679_117573_+	DUF1963 domain-containing protein	NA	NA	NA	NA
WP_143599530.1\|118698_119094_+	hypothetical protein	NA	NA	NA	NA
WP_143599531.1\|121145_121295_+	ferredoxin reductase	NA	NA	NA	NA
WP_143605099.1\|122668_123943_+	cytochrome P450	NA	NA	NA	NA
123241:123257	attL	NA	NA	NA	NA
WP_143599532.1\|124829_125417_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_143599533.1\|127438_128290_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143599534.1\|128766_128961_-	hypothetical protein	NA	NA	NA	NA
WP_143599535.1\|129333_130089_-	AAA family ATPase	NA	NA	NA	NA
WP_143599536.1\|130500_131004_+	hypothetical protein	NA	NA	NA	NA
WP_143599537.1\|131622_132003_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143599538.1\|132078_133008_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_143599539.1\|133354_134518_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1P8DJA0	Virus_Rctr71	8.3e-73	45.1
WP_054228646.1\|134995_135208_-	hypothetical protein	NA	NA	NA	NA
WP_143599540.1\|135393_135660_-	recombinase family protein	NA	NA	NA	NA
WP_143599541.1\|135970_136756_-	Ku protein	A0A2D1GE00	Mycobacterium_phage	7.4e-33	36.5
WP_143599542.1\|136955_137249_+	hypothetical protein	NA	NA	NA	NA
WP_143599543.1\|138120_139227_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_143599544.1\|140419_140701_+	hypothetical protein	NA	NA	NA	NA
WP_054228640.1\|140878_141310_-	cyclase	NA	NA	NA	NA
WP_054228639.1\|141664_141883_+	hypothetical protein	NA	NA	NA	NA
WP_054228638.1\|141987_142734_-	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_143599545.1\|144321_145179_+	hypothetical protein	NA	NA	NA	NA
WP_143599546.1\|145168_149332_+	hypothetical protein	NA	NA	NA	NA
WP_143599547.1\|149498_150812_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A7P9	Microcystis_virus	4.0e-47	35.6
WP_054228650.1\|151055_151406_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_097288518.1\|151621_151801_+	hypothetical protein	NA	NA	NA	NA
WP_143599548.1\|151834_152629_+	2-phosphosulfolactate phosphatase	NA	NA	NA	NA
WP_143599549.1\|152640_153051_-	STAS domain-containing protein	NA	NA	NA	NA
WP_054237178.1\|153086_153512_-	ATP-binding protein	NA	NA	NA	NA
WP_143599550.1\|153511_153919_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_143599551.1\|153915_155649_-	STAS domain-containing protein	A0A2H4J153	uncultured_Caudovirales_phage	1.0e-18	22.9
WP_054237181.1\|155645_155987_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143605100.1\|156146_156500_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_143599552.1\|157823_158423_+	MepB domain containing protein	NA	NA	NA	NA
WP_143599553.1\|158917_159772_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
159619:159635	attR	NA	NA	NA	NA
WP_143599554.1\|159968_160151_+	hypothetical protein	NA	NA	NA	NA
WP_143599555.1\|161771_162215_-	hypothetical protein	NA	NA	NA	NA
WP_143599556.1\|163674_164205_+	hypothetical protein	NA	NA	NA	NA
WP_097289555.1\|164387_164912_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_143599557.1\|164908_165601_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.5e-29	39.9
WP_143599558.1\|165597_167943_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_143599559.1\|169425_170643_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_143599560.1\|171390_172176_+	sel1 repeat family protein	NA	NA	NA	NA
WP_143599561.1\|172518_173016_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143599562.1\|173097_173571_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143605101.1\|173931_174273_-	DUF1707 domain-containing protein	NA	NA	NA	NA
WP_097288501.1\|174318_174888_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143599563.1\|175427_175970_+	hypothetical protein	NA	NA	NA	NA
WP_143599564.1\|175991_177587_-\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

935363 : 983816

Mycobacterium_phage(25.0%)

transposase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143600005.1\|935363_935777_+\|transposase	transposase	NA	NA	NA	NA
WP_143605156.1\|935797_936835_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_143600006.1\|936890_937535_+	peptidase M55	NA	NA	NA	NA
WP_143600007.1\|937535_938495_-	chlorophyllase	NA	NA	NA	NA
WP_143600008.1\|939013_939856_+	hypothetical protein	NA	NA	NA	NA
WP_143600009.1\|940079_941027_+	alpha/beta hydrolase fold domain-containing protein	NA	NA	NA	NA
WP_054229446.1\|941795_943127_-	aromatic acid/H+ symport family MFS transporter	NA	NA	NA	NA
WP_143600010.1\|943397_944363_-	catechol 2,3-dioxygenase	NA	NA	NA	NA
WP_143600011.1\|944373_945462_-	4-oxalomesaconate tautomerase	NA	NA	NA	NA
WP_143600012.1\|945458_946169_-	4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase	NA	NA	NA	NA
WP_143600013.1\|946165_946915_-	PIG-L family deacetylase	NA	NA	NA	NA
WP_143600014.1\|946963_947614_-	FCD domain-containing protein	NA	NA	NA	NA
WP_143605157.1\|949263_950121_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_143600015.1\|950339_951245_+	EamA family transporter	NA	NA	NA	NA
WP_097282724.1\|951454_951922_+	hypothetical protein	NA	NA	NA	NA
WP_143605158.1\|951952_952315_-	hypothetical protein	NA	NA	NA	NA
WP_143600016.1\|952490_953951_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	6.0e-20	28.7
WP_054229457.1\|954198_954777_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_097282726.1\|954883_955264_+	DoxX family membrane protein	NA	NA	NA	NA
WP_097282727.1\|955260_955728_+	peroxiredoxin	NA	NA	NA	NA
WP_097282728.1\|955783_956155_-	cupin domain-containing protein	NA	NA	NA	NA
WP_143600017.1\|956212_956596_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_143600018.1\|956655_957000_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_143600019.1\|957280_962833_+	hypothetical protein	NA	NA	NA	NA
WP_143600020.1\|962845_965680_-	AAA family ATPase	NA	NA	NA	NA
WP_054229465.1\|965869_966532_+	response regulator transcription factor	NA	NA	NA	NA
WP_143600021.1\|966665_967385_+	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_143600022.1\|967381_969478_+	AAA family ATPase	A0A1B2RW50	Lymphocystis_disease_virus	5.8e-08	30.9
WP_143600023.1\|969576_969783_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_143600024.1\|969800_971021_+\|transposase	transposase	A0A1D8ETH9	Propionibacterium_phage	1.4e-94	49.6
WP_143600025.1\|971081_972521_-	hydrolase	NA	NA	NA	NA
WP_143600026.1\|972613_974038_-	hydrogenase expression protein	NA	NA	NA	NA
WP_143600027.1\|974391_975825_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_143600028.1\|977099_978680_+\|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.3e-65	34.8
WP_054230236.1\|978745_979189_+\|tail	phage tail protein	NA	NA	NA	NA
WP_143600029.1\|979188_979671_+	hypothetical protein	NA	NA	NA	NA
WP_054235291.1\|983390_983816_+\|tail	phage tail protein	NA	NA	NA	NA

DBSCAN-SWA_4

1129236 : 1353304

173

Mycobacterium_phage(14.29%)

transposase,tRNA,protease,integrase

attL 1323531:1323546|attR 1356146:1356161

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143605172.1\|1129236_1130430_-\|transposase	transposase	I4AZI9	Saccharomonospora_phage	9.9e-37	33.4
WP_143600108.1\|1131597_1134420_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_097288697.1\|1134425_1135118_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.8e-36	40.7
WP_143600109.1\|1135216_1135846_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_097282842.1\|1136048_1136498_+	hypothetical protein	NA	NA	NA	NA
WP_143600110.1\|1136589_1136859_+	hypothetical protein	NA	NA	NA	NA
WP_143600111.1\|1137350_1137959_-	hypothetical protein	NA	NA	NA	NA
WP_143600112.1\|1138019_1138316_-	hypothetical protein	NA	NA	NA	NA
WP_143600113.1\|1139388_1140582_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0R8V9X2	Thermobifida_phage	4.0e-147	72.2
WP_143605173.1\|1141012_1141858_-	ATP-binding cassette domain-containing protein	M1HP82	Acanthocystis_turfacea_Chlorella_virus	8.3e-06	26.3
WP_067377257.1\|1141968_1142424_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_143600114.1\|1142595_1143501_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_143600115.1\|1143517_1144909_-	MFS transporter	NA	NA	NA	NA
WP_060900631.1\|1144946_1145558_-	LysE family transporter	NA	NA	NA	NA
WP_143600116.1\|1145624_1146533_+	ArgP/LysG family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_143600117.1\|1146790_1149334_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_143600118.1\|1149594_1150263_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_060900627.1\|1150370_1150724_+	hypothetical protein	NA	NA	NA	NA
WP_143600119.1\|1150815_1151028_-	hypothetical protein	NA	NA	NA	NA
WP_143600120.1\|1151324_1152518_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0R8V9X2	Thermobifida_phage	1.2e-146	71.9
WP_143600121.1\|1153542_1154370_+	hypothetical protein	NA	NA	NA	NA
WP_143605174.1\|1154889_1155858_-	hypothetical protein	NA	NA	NA	NA
WP_143600122.1\|1155988_1156327_+	hypothetical protein	NA	NA	NA	NA
WP_143600123.1\|1156535_1156964_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_143600124.1\|1157098_1157962_+	ANTAR domain-containing protein	NA	NA	NA	NA
WP_143600125.1\|1158057_1158375_+	plasmid stabilization protein	NA	NA	NA	NA
WP_143600126.1\|1158901_1159240_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_143600127.1\|1160501_1161077_+	DinB family protein	NA	NA	NA	NA
WP_143600128.1\|1161171_1162896_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_143600129.1\|1162955_1163285_+	hypothetical protein	NA	NA	NA	NA
WP_143600130.1\|1163555_1163801_-	hypothetical protein	NA	NA	NA	NA
WP_143600131.1\|1164171_1165305_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143600132.1\|1165392_1166166_-	hypothetical protein	NA	NA	NA	NA
WP_143600133.1\|1166162_1166774_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_143600134.1\|1167000_1167441_-	hypothetical protein	NA	NA	NA	NA
WP_143600135.1\|1167849_1168677_-	hypothetical protein	NA	NA	NA	NA
WP_143600136.1\|1168873_1169098_-	hypothetical protein	NA	NA	NA	NA
WP_143600137.1\|1170392_1171622_+	protein kinase	S4VV57	Pandoravirus	1.9e-14	32.0
WP_143600138.1\|1171966_1172311_+	hypothetical protein	NA	NA	NA	NA
WP_143600139.1\|1172283_1172481_+	hypothetical protein	NA	NA	NA	NA
WP_143600140.1\|1172569_1173319_+	SDR family NAD(P)-dependent oxidoreductase	F2NZ12	Diadromus_pulchellus_ascovirus	6.2e-05	26.0
WP_143600141.1\|1173844_1174684_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143600142.1\|1174931_1175525_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143600143.1\|1175630_1176368_+	NADP oxidoreductase	NA	NA	NA	NA
WP_143600144.1\|1176497_1176701_+	hypothetical protein	NA	NA	NA	NA
WP_143600145.1\|1176929_1177835_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_143600146.1\|1177912_1178974_+	alkene reductase	NA	NA	NA	NA
WP_099918061.1\|1178985_1179465_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143600147.1\|1179762_1180785_-	glycosyltransferase	NA	NA	NA	NA
WP_143600148.1\|1181379_1181640_-	hypothetical protein	NA	NA	NA	NA
WP_143600149.1\|1181636_1181942_-	hypothetical protein	NA	NA	NA	NA
WP_143600150.1\|1182508_1182769_+	hypothetical protein	NA	NA	NA	NA
WP_143600151.1\|1182932_1183433_+	DUF3761 domain-containing protein	NA	NA	NA	NA
WP_143600152.1\|1184292_1185831_-\|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_143600153.1\|1185904_1186432_-	hypothetical protein	NA	NA	NA	NA
WP_143605175.1\|1187001_1188117_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143600154.1\|1190428_1191847_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_143600155.1\|1192135_1193377_+	sodium:proton antiporter	NA	NA	NA	NA
WP_143600156.1\|1193387_1193690_+	hypothetical protein	NA	NA	NA	NA
WP_143600157.1\|1193617_1194514_+\|tRNA	tRNA-dependent cyclodipeptide synthase	NA	NA	NA	NA
WP_143600158.1\|1194503_1195688_+	cytochrome P450	NA	NA	NA	NA
WP_143600159.1\|1195707_1196547_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_143600160.1\|1196951_1198286_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143600161.1\|1198383_1199481_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143600162.1\|1199646_1201785_+	DUF559 domain-containing protein	A0A1B1P7Q7	Bacillus_phage	3.5e-24	27.2
WP_143600163.1\|1202007_1204317_+	protein kinase	A0A291AU40	Pandoravirus	1.8e-10	28.9
WP_143600164.1\|1205347_1205956_-	hypothetical protein	NA	NA	NA	NA
WP_143600165.1\|1205925_1215984_-	hypothetical protein	NA	NA	NA	NA
WP_143600166.1\|1216339_1217659_+	S8 family serine peptidase	NA	NA	NA	NA
WP_143600167.1\|1217777_1218260_+	hypothetical protein	NA	NA	NA	NA
WP_143600168.1\|1219575_1220202_+	hypothetical protein	NA	NA	NA	NA
WP_060895661.1\|1221353_1221854_-	hypothetical protein	NA	NA	NA	NA
WP_143600169.1\|1222986_1223253_+	hypothetical protein	NA	NA	NA	NA
WP_143600170.1\|1223523_1224165_-	hypothetical protein	NA	NA	NA	NA
WP_143600171.1\|1224602_1224893_-	barnase inhibitor	NA	NA	NA	NA
WP_143600172.1\|1224899_1228877_-	hypothetical protein	NA	NA	NA	NA
WP_143600173.1\|1229233_1230799_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_143605176.1\|1230849_1231239_-	hypothetical protein	NA	NA	NA	NA
WP_143600174.1\|1231987_1232581_-	hypothetical protein	NA	NA	NA	NA
WP_143600175.1\|1232666_1233713_-	hypothetical protein	NA	NA	NA	NA
WP_143600176.1\|1234457_1235129_-	hypothetical protein	NA	NA	NA	NA
WP_143600177.1\|1236142_1236667_+	hypothetical protein	NA	NA	NA	NA
WP_143600178.1\|1237492_1237897_+	hypothetical protein	NA	NA	NA	NA
WP_143600179.1\|1239770_1241024_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	1.5e-152	66.2
WP_143600180.1\|1241710_1243426_-	hypothetical protein	NA	NA	NA	NA
WP_143600181.1\|1243882_1244815_-	Ku protein	A0A249XRB2	Mycobacterium_phage	5.0e-36	35.6
WP_143600182.1\|1244926_1245802_+	DNA ligase	NA	NA	NA	NA
WP_143600183.1\|1245815_1246937_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_143600184.1\|1247141_1247354_+	hypothetical protein	NA	NA	NA	NA
WP_143600185.1\|1248005_1249109_+	hypothetical protein	NA	NA	NA	NA
WP_143600186.1\|1249614_1249968_-	hypothetical protein	NA	NA	NA	NA
WP_097283026.1\|1250036_1250210_-\|transposase	transposase	NA	NA	NA	NA
WP_143600187.1\|1251174_1253505_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_143600188.1\|1253839_1254364_+	hypothetical protein	NA	NA	NA	NA
WP_143600189.1\|1254723_1255335_+	hypothetical protein	NA	NA	NA	NA
WP_097283029.1\|1255960_1256578_+	RICIN domain-containing protein	NA	NA	NA	NA
WP_143600190.1\|1256707_1257721_-	Ig-like domain repeat protein	NA	NA	NA	NA
WP_143605178.1\|1259422_1259617_+	hypothetical protein	NA	NA	NA	NA
WP_143600191.1\|1259985_1260603_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143600192.1\|1260512_1261052_-\|transposase	transposase	NA	NA	NA	NA
WP_143600193.1\|1261357_1261765_+	hypothetical protein	NA	NA	NA	NA
WP_143600194.1\|1261880_1262177_-	hypothetical protein	NA	NA	NA	NA
WP_143600195.1\|1262444_1262657_-	hypothetical protein	NA	NA	NA	NA
WP_143600196.1\|1263111_1263315_-	cold-shock protein	Q9AZD3	Lactococcus_phage	4.3e-17	65.7
WP_143605180.1\|1265845_1266130_+	hypothetical protein	NA	NA	NA	NA
WP_143600197.1\|1266318_1267458_+	hypothetical protein	NA	NA	NA	NA
WP_143600198.1\|1267670_1268081_-	hypothetical protein	NA	NA	NA	NA
WP_143600199.1\|1268345_1268843_-	hypothetical protein	NA	NA	NA	NA
WP_143599717.1\|1270270_1271746_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.7e-46	33.0
WP_143605119.1\|1271868_1273398_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_143605118.1\|1273583_1273811_-	hypothetical protein	NA	NA	NA	NA
WP_143600200.1\|1273971_1274496_+	hypothetical protein	NA	NA	NA	NA
WP_143600201.1\|1274492_1275266_-	cell division protein ZapE	U5N3V8	Enterobacteria_phage	1.9e-28	33.6
WP_143600202.1\|1275262_1276861_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.3e-15	25.2
WP_143605182.1\|1277058_1277673_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_143600203.1\|1278101_1279262_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_143600204.1\|1279324_1281712_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_143605184.1\|1281735_1282251_+	hypothetical protein	NA	NA	NA	NA
WP_097283036.1\|1283625_1284498_-	universal stress protein	NA	NA	NA	NA
WP_097283037.1\|1284609_1285650_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_143600205.1\|1285960_1287769_+	coagulation factor 5/8 type domain-containing protein	NA	NA	NA	NA
WP_143600206.1\|1287791_1289042_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_143600207.1\|1289038_1291456_-	glycoside hydrolase family 95 protein	NA	NA	NA	NA
WP_143600208.1\|1291628_1293446_-	carbohydrate-binding protein	NA	NA	NA	NA
WP_097283041.1\|1293482_1294409_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_096240185.1\|1294405_1295374_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_143600209.1\|1295370_1296684_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_143600210.1\|1296806_1297985_-	ROK family protein	NA	NA	NA	NA
WP_143600211.1\|1298168_1300277_+	alpha-galactosidase	NA	NA	NA	NA
WP_097283045.1\|1300334_1300973_-	hypothetical protein	NA	NA	NA	NA
WP_143600212.1\|1301654_1304252_+	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	2.4e-35	31.1
WP_143600213.1\|1304609_1304987_-	hypothetical protein	NA	NA	NA	NA
WP_143600214.1\|1305347_1306037_+	DUF4232 domain-containing protein	NA	NA	NA	NA
WP_143605186.1\|1306665_1307880_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1P8DJA0	Virus_Rctr71	1.1e-62	39.6
WP_101913763.1\|1307928_1308285_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.4e-36	57.3
WP_097283049.1\|1308416_1308851_+	hypothetical protein	NA	NA	NA	NA
WP_097283050.1\|1308936_1309236_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143600215.1\|1309556_1310357_+	hypothetical protein	NA	NA	NA	NA
WP_143600216.1\|1310517_1311786_-	hypothetical protein	NA	NA	NA	NA
WP_143600217.1\|1312596_1313130_-	RICIN domain-containing protein	NA	NA	NA	NA
WP_143600218.1\|1313326_1314256_-	Ku protein	A0A249XRB2	Mycobacterium_phage	6.3e-39	37.8
WP_143600219.1\|1314367_1315246_+	DNA ligase	O64130	Bacillus_phage	5.4e-16	29.0
WP_143600220.1\|1315369_1316173_-	hypothetical protein	NA	NA	NA	NA
WP_143605188.1\|1316554_1317298_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_143605190.1\|1321048_1322080_+	hypothetical protein	NA	NA	NA	NA
WP_143600221.1\|1322331_1322571_-	hypothetical protein	NA	NA	NA	NA
WP_143600222.1\|1323401_1324151_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	5.3e-12	28.1
1323531:1323546	attL	NA	NA	NA	NA
WP_143600223.1\|1324301_1325987_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_143600224.1\|1326108_1326744_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143600225.1\|1326803_1327031_-	hypothetical protein	NA	NA	NA	NA
WP_143600226.1\|1327156_1327600_-	hypothetical protein	NA	NA	NA	NA
WP_143600227.1\|1328148_1328982_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_143600228.1\|1329239_1329857_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143600229.1\|1330258_1330708_-	hypothetical protein	NA	NA	NA	NA
WP_143600230.1\|1331748_1332750_-	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_143600231.1\|1332795_1333500_-	NADP oxidoreductase	NA	NA	NA	NA
WP_143600232.1\|1333520_1334537_-	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_143600233.1\|1334844_1335528_-	hypothetical protein	NA	NA	NA	NA
WP_143600234.1\|1335555_1337121_-	hypothetical protein	NA	NA	NA	NA
WP_143600235.1\|1337120_1337738_-	hypothetical protein	NA	NA	NA	NA
WP_143600236.1\|1337734_1338613_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_143600237.1\|1339114_1339801_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_143600238.1\|1340325_1340613_-	hypothetical protein	NA	NA	NA	NA
WP_143600239.1\|1340908_1341715_-	hypothetical protein	NA	NA	NA	NA
WP_143600240.1\|1342409_1343096_+	hypothetical protein	NA	NA	NA	NA
WP_143600241.1\|1343195_1343879_+	phosphotransferase	NA	NA	NA	NA
WP_143600242.1\|1344731_1345001_+	hypothetical protein	NA	NA	NA	NA
WP_143605192.1\|1345020_1346004_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_143600243.1\|1346134_1347121_-	phosphotransferase	NA	NA	NA	NA
WP_143600244.1\|1347220_1347667_-	hypothetical protein	NA	NA	NA	NA
WP_143605194.1\|1347663_1349793_-\|integrase	integrase SAM domain protein	NA	NA	NA	NA
WP_143600245.1\|1349792_1351682_-	hypothetical protein	NA	NA	NA	NA
WP_143600246.1\|1351678_1353304_-\|integrase	integrase	NA	NA	NA	NA
1356146:1356161	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1369301 : 1410382

Wolbachia_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143600261.1\|1369301_1370870_+\|transposase	transposase	NA	NA	NA	NA
WP_143600262.1\|1370796_1371048_-	hypothetical protein	NA	NA	NA	NA
WP_143600263.1\|1372257_1372863_+	hypothetical protein	NA	NA	NA	NA
WP_143600264.1\|1374632_1375463_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_143600265.1\|1375464_1375983_-	hypothetical protein	NA	NA	NA	NA
WP_143600266.1\|1376003_1376732_-	hypothetical protein	NA	NA	NA	NA
WP_143600267.1\|1377103_1377613_+	DUF2269 domain-containing protein	NA	NA	NA	NA
WP_143600268.1\|1378981_1379452_-	hypothetical protein	NA	NA	NA	NA
WP_143600269.1\|1379736_1380489_-	hypothetical protein	NA	NA	NA	NA
WP_143600270.1\|1381718_1382609_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_143605195.1\|1383725_1383923_+	hypothetical protein	NA	NA	NA	NA
WP_143600271.1\|1385046_1386108_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143600272.1\|1386826_1387324_-	hypothetical protein	NA	NA	NA	NA
WP_143600273.1\|1388034_1388970_+\|transposase	transposase	NA	NA	NA	NA
WP_143600274.1\|1389121_1390357_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143600275.1\|1390532_1391846_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	4.0e-39	31.0
WP_143600276.1\|1393049_1393349_+	hypothetical protein	NA	NA	NA	NA
WP_143600277.1\|1393628_1394720_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143600278.1\|1394821_1395689_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.5e-18	40.2
WP_143605197.1\|1395730_1396108_-	hypothetical protein	NA	NA	NA	NA
WP_143600279.1\|1397772_1398282_-	hypothetical protein	NA	NA	NA	NA
WP_143600280.1\|1398378_1398882_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_143600281.1\|1399371_1399764_+	hypothetical protein	NA	NA	NA	NA
WP_143600282.1\|1399785_1399968_+	hypothetical protein	NA	NA	NA	NA
WP_143600283.1\|1400335_1400992_-	hypothetical protein	NA	NA	NA	NA
WP_143600284.1\|1401171_1401573_+	hypothetical protein	NA	NA	NA	NA
WP_143600285.1\|1401676_1401940_-	hypothetical protein	NA	NA	NA	NA
WP_143605199.1\|1401936_1402242_-	hypothetical protein	NA	NA	NA	NA
WP_143600286.1\|1403660_1404242_-	ricin-type beta-trefoil lectin domain protein	NA	NA	NA	NA
WP_143605200.1\|1404736_1406212_+	PucR family transcriptional regulator	NA	NA	NA	NA
WP_143600287.1\|1406208_1406532_+	hypothetical protein	NA	NA	NA	NA
WP_143600288.1\|1407136_1407418_+	hypothetical protein	NA	NA	NA	NA
WP_143600289.1\|1407556_1408390_-	hypothetical protein	NA	NA	NA	NA
WP_143605203.1\|1408910_1409900_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_143600290.1\|1409968_1410382_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1431698 : 1504883

Mycobacterium_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143605207.1\|1431698_1433117_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.6e-31	34.4
WP_143600304.1\|1432995_1433433_+\|transposase	transposase	A0A2P1JR32	Mycobacterium_phage	3.1e-20	56.2
WP_143605209.1\|1433529_1433742_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_143600305.1\|1433771_1434308_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_143600306.1\|1434934_1435414_-	hypothetical protein	NA	NA	NA	NA
WP_143600307.1\|1435694_1440575_-	virulence factor	NA	NA	NA	NA
WP_143605211.1\|1441686_1441824_+	hypothetical protein	NA	NA	NA	NA
WP_143600308.1\|1441840_1442104_-\|transposase	transposase	NA	NA	NA	NA
WP_143600309.1\|1442150_1442378_-	accessory factor UbiK family protein	NA	NA	NA	NA
WP_143600310.1\|1442690_1443314_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_143600311.1\|1443342_1443912_-	DUF4265 domain-containing protein	NA	NA	NA	NA
WP_143600312.1\|1444027_1444390_-	ferrous iron transport protein A	NA	NA	NA	NA
WP_143600313.1\|1444434_1444953_-	hypothetical protein	NA	NA	NA	NA
WP_143600314.1\|1445680_1446412_+	hypothetical protein	NA	NA	NA	NA
WP_143600315.1\|1446522_1447992_-	N-6 DNA methylase	A0A220A2U4	Liberibacter_phage	5.8e-47	31.0
WP_143600316.1\|1447988_1449170_-	hypothetical protein	NA	NA	NA	NA
WP_143605213.1\|1449166_1450381_-	N-6 DNA methylase	NA	NA	NA	NA
WP_107308822.1\|1450536_1450734_-	hypothetical protein	NA	NA	NA	NA
WP_143600153.1\|1453816_1454344_+	hypothetical protein	NA	NA	NA	NA
WP_143600152.1\|1454417_1455956_+\|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_143600317.1\|1456128_1456752_+	hypothetical protein	NA	NA	NA	NA
WP_143600318.1\|1457814_1458102_-	hypothetical protein	NA	NA	NA	NA
WP_143600319.1\|1459270_1461115_-	glycoside hydrolase family 15 protein	NA	NA	NA	NA
WP_143600320.1\|1461377_1462052_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_143605215.1\|1462048_1462552_-	hypothetical protein	NA	NA	NA	NA
WP_143600321.1\|1462554_1463979_-	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_143600322.1\|1464190_1464634_+	hypothetical protein	NA	NA	NA	NA
WP_143605217.1\|1465054_1466257_+	SidA/IucD/PvdA family monooxygenase	NA	NA	NA	NA
WP_143600323.1\|1466968_1467289_-	hypothetical protein	NA	NA	NA	NA
WP_143600324.1\|1467656_1468544_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_054237249.1\|1468712_1468928_+	4-oxalocrotonate tautomerase family protein	NA	NA	NA	NA
WP_143600325.1\|1469063_1471667_-	MMPL family transporter	Q19CT9	Aeromonas_virus	3.6e-07	43.9
WP_143600326.1\|1471900_1473226_-	serine hydrolase	G1DB24	Mycobacterium_phage	1.3e-26	34.0
WP_143600327.1\|1473537_1474875_+	sensor histidine kinase	NA	NA	NA	NA
WP_143600328.1\|1474859_1475504_+	response regulator	NA	NA	NA	NA
WP_143600329.1\|1475585_1475936_-	hypothetical protein	NA	NA	NA	NA
WP_143605220.1\|1475998_1477246_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	I4AZM3	Saccharomonospora_phage	2.4e-78	48.6
WP_143600330.1\|1477274_1477691_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	6.9e-38	57.0
WP_143600331.1\|1478197_1482469_+	Secreted glycosyl hydrolase	A0A2D1GD28	Mycobacterium_phage	9.4e-05	29.3
WP_143600332.1\|1482542_1483904_-	hypothetical protein	NA	NA	NA	NA
WP_097283169.1\|1484792_1486046_-	hypothetical protein	NA	NA	NA	NA
WP_097283170.1\|1486953_1487445_+	DUF2975 domain-containing protein	NA	NA	NA	NA
WP_054237256.1\|1487444_1487666_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143600333.1\|1488440_1489277_-	hypothetical protein	NA	NA	NA	NA
WP_143600334.1\|1489688_1490537_-	ABC transporter permease	NA	NA	NA	NA
WP_143600335.1\|1491782_1493099_+	hypothetical protein	NA	NA	NA	NA
WP_143605222.1\|1495669_1495822_+	ATP-dependent DNA ligase	NA	NA	NA	NA
WP_143600336.1\|1496214_1497114_+	hypothetical protein	NA	NA	NA	NA
WP_143600337.1\|1498027_1498789_-	hypothetical protein	NA	NA	NA	NA
WP_143600338.1\|1498806_1499307_+\|transposase	transposase	NA	NA	NA	NA
WP_143600339.1\|1499219_1499666_-	hypothetical protein	NA	NA	NA	NA
WP_143600340.1\|1500242_1500833_+	isochorismatase family protein	NA	NA	NA	NA
WP_143600341.1\|1501180_1503406_+	hypothetical protein	NA	NA	NA	NA
WP_143605224.1\|1503626_1504883_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.8e-36	39.2

DBSCAN-SWA_7

1648073 : 1670666

Tupanvirus(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143605245.1\|1648073_1649291_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143605247.1\|1649490_1650594_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143600458.1\|1650708_1651146_-	hypothetical protein	NA	NA	NA	NA
WP_143605249.1\|1651369_1652581_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_143600459.1\|1653487_1654735_+	sensor histidine kinase	NA	NA	NA	NA
WP_143600460.1\|1654722_1655373_+	response regulator	NA	NA	NA	NA
WP_143605245.1\|1655587_1656805_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143600461.1\|1657112_1658393_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_097287586.1\|1659580_1660021_-	VOC family protein	NA	NA	NA	NA
WP_143600462.1\|1662375_1663572_-	TIGR03118 family protein	L7Y4N7	Megavirus	7.8e-26	26.2
WP_143600463.1\|1663849_1665271_-	M1 family metallopeptidase	A0A2K9L1R3	Tupanvirus	2.7e-17	23.9
WP_143605251.1\|1665267_1669257_-	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	9.6e-36	28.7
WP_097283229.1\|1669836_1670166_-\|transposase	transposase	NA	NA	NA	NA
WP_143600464.1\|1670279_1670666_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

10076027 : 10148493

Streptomyces_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143604141.1\|10076027_10076288_-\|transposase	transposase	NA	NA	NA	NA
WP_054233508.1\|10076253_10076448_-	hypothetical protein	NA	NA	NA	NA
WP_143604142.1\|10076444_10076690_-	hypothetical protein	NA	NA	NA	NA
WP_060895339.1\|10076836_10077121_+	Sec-independent protein translocase subunit TatA	NA	NA	NA	NA
WP_143604143.1\|10077986_10079468_+	LytR family transcriptional regulator	NA	NA	NA	NA
WP_143604144.1\|10080090_10082892_+	SpoIIE family protein phosphatase	A0A1J0MCT1	Streptomyces_phage	1.3e-07	45.8
WP_143604145.1\|10083574_10083778_+	cold-shock protein	Q9AZD3	Lactococcus_phage	3.0e-10	54.1
WP_143605769.1\|10083953_10084994_+	acyl-CoA desaturase	A6N231	Microbacterium_phage	2.6e-73	45.8
WP_143604146.1\|10085704_10086124_-\|transposase	transposase	NA	NA	NA	NA
WP_143604147.1\|10086458_10087136_-	hypothetical protein	NA	NA	NA	NA
WP_143604148.1\|10089208_10091857_+	lantipeptide synthetase	NA	NA	NA	NA
WP_054233519.1\|10091938_10092055_+	SapB/AmfS family lantipeptide	NA	NA	NA	NA
WP_143604149.1\|10092261_10093974_+	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_143605770.1\|10094063_10095881_+	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_143604150.1\|10095719_10096328_-	response regulator transcription factor	NA	NA	NA	NA
WP_097287809.1\|10096537_10096804_-	hypothetical protein	NA	NA	NA	NA
WP_143604151.1\|10097031_10098675_+	amino acid permease	NA	NA	NA	NA
WP_143604152.1\|10099902_10100109_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_097287810.1\|10100306_10101002_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_143604153.1\|10101264_10101648_+	hypothetical protein	NA	NA	NA	NA
WP_060897681.1\|10104109_10104589_-	winged helix DNA-binding protein	NA	NA	NA	NA
WP_143604154.1\|10104671_10105571_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_097287814.1\|10106122_10106362_+	DUF5302 domain-containing protein	NA	NA	NA	NA
WP_143604155.1\|10106447_10106639_-	hypothetical protein	NA	NA	NA	NA
WP_143604156.1\|10111928_10112318_+	hypothetical protein	NA	NA	NA	NA
WP_143604157.1\|10112598_10113021_+	SsgA family sporulation/cell division regulator	NA	NA	NA	NA
WP_097287820.1\|10113141_10113846_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_143604158.1\|10114125_10115193_+	hypothetical protein	NA	NA	NA	NA
WP_143605771.1\|10115251_10115689_-\|transposase	transposase	NA	NA	NA	NA
WP_143604159.1\|10115716_10116487_-\|transposase	transposase	NA	NA	NA	NA
WP_143600277.1\|10116527_10117619_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143604160.1\|10118516_10120352_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_143605772.1\|10121573_10122233_-	hypothetical protein	NA	NA	NA	NA
WP_143604161.1\|10122450_10122750_-	hypothetical protein	NA	NA	NA	NA
WP_143604162.1\|10122829_10123852_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_143604163.1\|10123927_10124764_-	ATP-binding cassette domain-containing protein	F2Y1V6	Organic_Lake_phycodnavirus	6.3e-06	24.3
WP_054228398.1\|10124760_10125756_-	ABC transporter permease	NA	NA	NA	NA
WP_143604164.1\|10125887_10126904_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_143604165.1\|10127151_10128159_+	carbohydrate kinase	NA	NA	NA	NA
WP_143604166.1\|10128361_10130923_+	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	4.6e-23	34.3
WP_054228394.1\|10130978_10131272_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_143604167.1\|10131791_10132343_+	DUF4231 domain-containing protein	NA	NA	NA	NA
WP_143604168.1\|10133536_10135990_+	hypothetical protein	NA	NA	NA	NA
WP_143605773.1\|10136295_10136796_-	hypothetical protein	NA	NA	NA	NA
WP_143604169.1\|10137633_10138971_+	hypothetical protein	NA	NA	NA	NA
WP_143604170.1\|10139209_10139494_-	hypothetical protein	NA	NA	NA	NA
WP_143599674.1\|10140481_10141024_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143604171.1\|10141970_10142411_-	hypothetical protein	NA	NA	NA	NA
WP_143604172.1\|10142598_10142787_-	hypothetical protein	NA	NA	NA	NA
WP_143604173.1\|10142783_10143020_-	hypothetical protein	NA	NA	NA	NA
WP_143605774.1\|10144595_10145984_+	hypothetical protein	NA	NA	NA	NA
WP_143605775.1\|10147455_10148493_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

11095806 : 11163350

Caulobacter_phage(40.0%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143604719.1\|11095806_11097258_+\|transposase	transposase	NA	NA	NA	NA
WP_143604720.1\|11098169_11098571_+	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_143604721.1\|11098949_11099924_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604722.1\|11100003_11100594_+	carbonic anhydrase	NA	NA	NA	NA
WP_143604723.1\|11101416_11102130_+	hypothetical protein	NA	NA	NA	NA
WP_143604724.1\|11102377_11102827_+	Tellurite resistance TerB	NA	NA	NA	NA
WP_143604725.1\|11102962_11103895_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_143604726.1\|11103902_11104292_-	BlaI/MecI/CopY family transcriptional regulator	NA	NA	NA	NA
WP_060894503.1\|11104994_11105570_+	TerD family protein	K4JRX3	Caulobacter_phage	5.4e-33	40.5
WP_143604727.1\|11105679_11106300_+	hypothetical protein	NA	NA	NA	NA
WP_143604728.1\|11106341_11106923_+	TerD family protein	A0A2P1N0C0	Streptomyces_phage	4.0e-07	28.6
WP_097282100.1\|11106958_11107225_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_143604729.1\|11107494_11107857_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_143604730.1\|11108622_11109054_-	Sec-independent protein translocase subunit TatB	NA	NA	NA	NA
WP_143604731.1\|11109209_11109785_+	TerD family protein	K4JRX3	Caulobacter_phage	9.9e-35	43.8
WP_079089155.1\|11110587_11110812_-	Sec-independent protein translocase TatA	NA	NA	NA	NA
WP_101913760.1\|11112490_11112670_-	hypothetical protein	NA	NA	NA	NA
WP_143604732.1\|11112707_11114135_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_143604733.1\|11114257_11115163_+	heavy metal transporter	A0A223FZV2	Streptomyces_phage	3.3e-24	50.4
WP_143604734.1\|11119032_11119668_-	3-oxoacid CoA-transferase subunit B	NA	NA	NA	NA
WP_143604735.1\|11119664_11120447_-	3-oxoacid CoA-transferase subunit A	NA	NA	NA	NA
WP_143604736.1\|11121232_11122207_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_143604737.1\|11122295_11123258_-	oxidoreductase	NA	NA	NA	NA
WP_143604738.1\|11123269_11124304_-	amidohydrolase family protein	NA	NA	NA	NA
WP_143604739.1\|11124300_11125470_-	2-polyprenyl-6-methoxyphenol hydroxylase	NA	NA	NA	NA
WP_143604740.1\|11125590_11126571_-	cyclase family protein	NA	NA	NA	NA
WP_143604741.1\|11126567_11127566_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_143604742.1\|11127701_11128646_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_143604743.1\|11128758_11130042_+	MFS transporter	NA	NA	NA	NA
WP_097282087.1\|11131147_11132164_-	DNA-directed RNA polymerase subunit alpha	NA	NA	NA	NA
WP_143604744.1\|11132646_11133585_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_143605845.1\|11133883_11134675_+\|transposase	transposase	NA	NA	NA	NA
WP_143604745.1\|11134829_11135492_-	arsenate reductase ArsC	NA	NA	NA	NA
WP_143604746.1\|11135947_11136193_-	DUF2283 domain-containing protein	NA	NA	NA	NA
WP_143604747.1\|11137725_11138709_-	AsnC family transcriptional regulator	NA	NA	NA	NA
WP_143604748.1\|11139321_11140941_+	amidohydrolase family protein	NA	NA	NA	NA
WP_097282082.1\|11141597_11142218_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_143604749.1\|11142653_11144090_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_143604750.1\|11144163_11145789_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	4.0e-49	28.6
WP_143604751.1\|11146217_11146766_-	DUF1062 domain-containing protein	NA	NA	NA	NA
WP_060894546.1\|11147484_11147736_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_060894523.1\|11147738_11148110_+	hypothetical protein	NA	NA	NA	NA
WP_143604752.1\|11148485_11148938_+	hypothetical protein	NA	NA	NA	NA
WP_143604753.1\|11148934_11149153_-	hypothetical protein	NA	NA	NA	NA
WP_060894525.1\|11149858_11150815_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604754.1\|11150925_11151924_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_143604755.1\|11152727_11154293_-	MFS transporter	NA	NA	NA	NA
WP_143604756.1\|11154350_11155703_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_097282074.1\|11155875_11156736_-	PaaX family transcriptional regulator	NA	NA	NA	NA
WP_060894529.1\|11158067_11158727_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_143604757.1\|11158903_11159284_+	hypothetical protein	NA	NA	NA	NA
WP_143604758.1\|11159882_11161121_+	hypothetical protein	NA	NA	NA	NA
WP_143605245.1\|11161295_11162513_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143604759.1\|11162978_11163350_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_10

11243807 : 11300145

Klosneuvirus(25.0%)

transposase,integrase

attL 11242123:11242140|attR 11308952:11308969

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
11242123:11242140	attL	NA	NA	NA	NA
WP_143604808.1\|11243807_11244647_+\|transposase	transposase	NA	NA	NA	NA
WP_143604809.1\|11245061_11245508_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_143604810.1\|11245745_11246357_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143605851.1\|11249167_11250673_+	NAD(P)-binding protein	A0A1V0SI18	Klosneuvirus	2.0e-55	33.8
WP_097281999.1\|11250874_11251555_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604811.1\|11251587_11252100_+	DUF3291 domain-containing protein	NA	NA	NA	NA
WP_143604812.1\|11252133_11252607_-	hypothetical protein	NA	NA	NA	NA
WP_143604813.1\|11252940_11253444_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143604814.1\|11254005_11254404_+	hypothetical protein	NA	NA	NA	NA
WP_143604815.1\|11254527_11255064_-	hypothetical protein	NA	NA	NA	NA
WP_143604816.1\|11256142_11256871_-	DUF2625 family protein	NA	NA	NA	NA
WP_143605852.1\|11257491_11258001_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_143604817.1\|11260236_11261409_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_143604818.1\|11261325_11261967_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_143604819.1\|11261923_11262460_-	hypothetical protein	NA	NA	NA	NA
WP_143605853.1\|11262737_11263724_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604820.1\|11264227_11264884_+	hypothetical protein	NA	NA	NA	NA
WP_143604821.1\|11265210_11265519_-	hypothetical protein	NA	NA	NA	NA
WP_054236303.1\|11265786_11266125_-	thiol reductase thioredoxin	NA	NA	NA	NA
WP_143604822.1\|11266340_11266925_+	hypothetical protein	NA	NA	NA	NA
WP_143604823.1\|11266961_11267087_-	cytochrome P450	NA	NA	NA	NA
WP_143604824.1\|11267293_11269000_+	MFS transporter	NA	NA	NA	NA
WP_143604825.1\|11269750_11271073_+	nucleotide sugar dehydrogenase	A0A1J0FA55	Only_Syngen_Nebraska_virus	5.8e-30	25.2
WP_143604826.1\|11271146_11271572_+	hypothetical protein	E3SL71	Synechococcus_phage	9.3e-06	49.1
WP_143604827.1\|11271573_11271885_+	NUDIX hydrolase	NA	NA	NA	NA
WP_143604828.1\|11273628_11274225_-	NADP oxidoreductase	NA	NA	NA	NA
WP_143604829.1\|11274266_11275085_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_143604830.1\|11275224_11276130_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_143604831.1\|11276401_11277130_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143604832.1\|11277241_11278375_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_143604833.1\|11279807_11280059_-	hypothetical protein	NA	NA	NA	NA
WP_143604834.1\|11283132_11283675_-	hypothetical protein	NA	NA	NA	NA
WP_054236290.1\|11283904_11284312_+	SgcJ/EcaC family oxidoreductase	NA	NA	NA	NA
WP_143604835.1\|11284380_11285343_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_143604836.1\|11285541_11286225_-	adenylate kinase	NA	NA	NA	NA
WP_143604837.1\|11286540_11287116_-\|transposase	transposase	NA	NA	NA	NA
WP_143604838.1\|11287232_11287598_+	hypothetical protein	NA	NA	NA	NA
WP_143604839.1\|11288105_11288489_-	DUF4440 domain-containing protein	NA	NA	NA	NA
WP_143604840.1\|11291093_11292362_-	cytochrome P450	NA	NA	NA	NA
WP_143604841.1\|11292584_11294282_+	monooxygenase	NA	NA	NA	NA
WP_143604842.1\|11294321_11295329_+	amidohydrolase family protein	NA	NA	NA	NA
WP_143604843.1\|11295449_11295986_+	hypothetical protein	NA	NA	NA	NA
WP_143605854.1\|11295942_11296839_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_143604844.1\|11297248_11297677_-	hypothetical protein	NA	NA	NA	NA
WP_143605855.1\|11297857_11298784_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_143604845.1\|11298906_11300145_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.1e-82	43.9
11308952:11308969	attR	NA	NA	NA	NA

DBSCAN-SWA_11

11314941 : 11368082

Streptococcus_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143604855.1\|11314941_11315661_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.1e-27	34.0
WP_143604856.1\|11315869_11316169_-	hypothetical protein	A0A142KA45	Gordonia_phage	9.7e-10	50.6
WP_143604857.1\|11316566_11317301_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_143604858.1\|11317606_11318734_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143604859.1\|11318771_11319020_-	hypothetical protein	NA	NA	NA	NA
WP_143604860.1\|11319410_11320385_-	hypothetical protein	NA	NA	NA	NA
WP_143604861.1\|11320445_11321117_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143604862.1\|11321244_11321547_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_143604863.1\|11321856_11322690_-	AAA family ATPase	NA	NA	NA	NA
WP_143604864.1\|11322922_11323660_-	hypothetical protein	NA	NA	NA	NA
WP_143605857.1\|11324775_11326371_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.1e-17	25.6
WP_143604865.1\|11326367_11327141_+	AAA family ATPase	U5N3V8	Enterobacteria_phage	2.0e-30	34.4
WP_143604866.1\|11327175_11327712_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143604867.1\|11328143_11329646_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_143604868.1\|11330964_11331870_+\|transposase	transposase	NA	NA	NA	NA
WP_143604869.1\|11331912_11333157_-	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_143604870.1\|11333511_11334063_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143604871.1\|11334763_11335531_-	hypothetical protein	NA	NA	NA	NA
WP_143604872.1\|11335724_11337155_-	selenium-binding protein	NA	NA	NA	NA
WP_143604873.1\|11339070_11339931_-	hypothetical protein	NA	NA	NA	NA
WP_143604874.1\|11340002_11340722_+\|transposase	IS6 family transposase	NA	NA	NA	NA
WP_143604875.1\|11341094_11341436_+	hypothetical protein	NA	NA	NA	NA
WP_097281962.1\|11343061_11343697_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143604876.1\|11344414_11345281_+	AfsR/SARP family transcriptional regulator	NA	NA	NA	NA
WP_143604877.1\|11345544_11346480_+	hypothetical protein	NA	NA	NA	NA
WP_143604878.1\|11346304_11346919_+\|transposase	transposase	NA	NA	NA	NA
WP_143605858.1\|11347540_11347816_+	hypothetical protein	NA	NA	NA	NA
WP_143604879.1\|11348185_11348908_+	hypothetical protein	NA	NA	NA	NA
WP_143604880.1\|11355673_11357218_+	hypothetical protein	NA	NA	NA	NA
WP_054231735.1\|11357625_11358438_+	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_097288591.1\|11362112_11362934_-	AfsR/SARP family transcriptional regulator	NA	NA	NA	NA
WP_143604881.1\|11363545_11363740_+	acyl-CoA carboxylase subunit epsilon	NA	NA	NA	NA
WP_143605859.1\|11363941_11365486_+	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_143604882.1\|11365814_11366639_+	AfsR/SARP family transcriptional regulator	NA	NA	NA	NA
WP_143604883.1\|11366888_11368082_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0R8V9X2	Thermobifida_phage	3.2e-144	73.2

DBSCAN-SWA_12

11403084 : 11438380

Saccharomonospora_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143605860.1\|11403084_11404278_-\|transposase	transposase	I4AZI9	Saccharomonospora_phage	7.5e-37	33.4
WP_143604899.1\|11404431_11405046_+	dTDP-4-keto-6-deoxy-D-glucose epimerase	H9NC63	Sphingomonas_phage	1.0e-13	38.4
WP_143604900.1\|11405078_11405525_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_143604901.1\|11405913_11406336_-\|transposase	IS200/IS605 family transposase	I4AZM1	Saccharomonospora_phage	8.5e-44	64.7
WP_143604902.1\|11406387_11407587_+\|transposase	transposase	A0A220NS37	Mycobacterium_phage	1.4e-30	31.8
WP_101913755.1\|11407719_11407974_-	hypothetical protein	NA	NA	NA	NA
WP_143604903.1\|11408360_11409692_+	hypothetical protein	NA	NA	NA	NA
WP_143604904.1\|11410589_11411132_+	hypothetical protein	NA	NA	NA	NA
WP_143599458.1\|11411229_11412414_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_143604905.1\|11413924_11414398_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_060899423.1\|11414527_11415520_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	6.0e-72	44.9
WP_054230033.1\|11415754_11416822_-	glucose-1-phosphate thymidylyltransferase	A0A1D7XFC1	Escherichia_phage	2.5e-39	40.0
WP_067383410.1\|11416988_11417411_+	ester cyclase	NA	NA	NA	NA
WP_143604906.1\|11417547_11418537_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_060900329.1\|11418566_11419967_-	NDP-hexose 2,3-dehydratase	NA	NA	NA	NA
WP_143604907.1\|11420161_11421346_+	glycosyltransferase	NA	NA	NA	NA
WP_143604908.1\|11421799_11422222_+	hypothetical protein	NA	NA	NA	NA
WP_143604909.1\|11422872_11423535_+	isochorismatase family protein	NA	NA	NA	NA
WP_143604910.1\|11423840_11424164_+	hypothetical protein	NA	NA	NA	NA
WP_143605861.1\|11424226_11424847_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_143604911.1\|11424943_11426833_+	amidohydrolase family protein	NA	NA	NA	NA
WP_075032155.1\|11426886_11427381_+	DoxX family protein	NA	NA	NA	NA
WP_143605862.1\|11427507_11427954_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_143604912.1\|11428416_11429340_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_143605863.1\|11429399_11429765_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_143604913.1\|11430830_11432057_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_143604914.1\|11433040_11434654_-	hypothetical protein	NA	NA	NA	NA
WP_143604915.1\|11434826_11435432_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143604916.1\|11435501_11435963_-	DUF2871 family protein	NA	NA	NA	NA
WP_143604917.1\|11437222_11438380_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1P8DJG9	Virus_Rctr71	1.4e-67	45.3

DBSCAN-SWA_13

11469028 : 11536435

Microcystis_virus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143604933.1\|11469028_11470342_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A7P9	Microcystis_virus	1.2e-46	35.6
WP_143605866.1\|11470656_11472039_+	hypothetical protein	NA	NA	NA	NA
WP_097281893.1\|11472158_11472632_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_143604934.1\|11472672_11473056_+	DoxX family protein	NA	NA	NA	NA
WP_097281891.1\|11474209_11474944_-	DUF1345 domain-containing protein	NA	NA	NA	NA
WP_143604935.1\|11475576_11476113_-	hypothetical protein	NA	NA	NA	NA
WP_143604936.1\|11476448_11477024_+	transcriptional regulator	NA	NA	NA	NA
WP_054229772.1\|11477169_11477340_+	hypothetical protein	NA	NA	NA	NA
WP_143604937.1\|11477684_11478353_+	peptidase E	NA	NA	NA	NA
WP_143604938.1\|11478426_11478696_+	hypothetical protein	NA	NA	NA	NA
WP_143604939.1\|11478903_11479548_-	hypothetical protein	NA	NA	NA	NA
WP_143604940.1\|11479907_11480111_-	hypothetical protein	NA	NA	NA	NA
WP_143604941.1\|11480260_11480929_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_143604942.1\|11481149_11483210_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_143604943.1\|11483499_11483889_+	hypothetical protein	NA	NA	NA	NA
WP_143604944.1\|11484070_11485009_-	hypothetical protein	NA	NA	NA	NA
WP_097287833.1\|11485766_11486258_+	DUF4231 domain-containing protein	NA	NA	NA	NA
WP_143604945.1\|11486590_11487562_-	WYL domain-containing protein	NA	NA	NA	NA
WP_143604946.1\|11487641_11488376_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_143605867.1\|11488406_11488961_+	winged helix DNA-binding domain-containing protein	NA	NA	NA	NA
WP_143604947.1\|11488994_11489570_+\|transposase	IS607 family transposase	F9VHY9	Thermus_phage	6.6e-23	36.8
WP_143604948.1\|11489566_11491024_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A7P9	Microcystis_virus	4.4e-39	33.3
WP_097281887.1\|11491573_11491936_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_143604949.1\|11491932_11493366_+	MFS transporter	NA	NA	NA	NA
WP_143604950.1\|11493399_11493693_+	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_060895859.1\|11493938_11495525_-	Na+/H+ antiporter	NA	NA	NA	NA
WP_143604951.1\|11495947_11496244_-	hypothetical protein	NA	NA	NA	NA
WP_143604952.1\|11497672_11498299_-	hypothetical protein	NA	NA	NA	NA
WP_143604953.1\|11498338_11498584_+\|transposase	transposase	NA	NA	NA	NA
WP_143604954.1\|11498632_11499235_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604955.1\|11499204_11499759_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143604956.1\|11499864_11500686_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604957.1\|11500799_11501741_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_143599674.1\|11502452_11502995_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143604958.1\|11504676_11505207_+	SRPBCC family protein	NA	NA	NA	NA
WP_143604959.1\|11505492_11505960_+	cupin domain-containing protein	NA	NA	NA	NA
WP_143604960.1\|11507217_11507556_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_143605868.1\|11508547_11508898_-	hypothetical protein	NA	NA	NA	NA
WP_143604961.1\|11509943_11511470_+	TIGR02677 family protein	NA	NA	NA	NA
WP_143604962.1\|11511555_11513010_+	TIGR02678 family protein	NA	NA	NA	NA
WP_143605869.1\|11513024_11517179_+	TIGR02680 family protein	NA	NA	NA	NA
WP_143604963.1\|11517168_11518461_+	TIGR02679 family protein	NA	NA	NA	NA
WP_143604964.1\|11518666_11519809_+	Fic family protein	A0A1V0E025	Clostridioides_phage	1.5e-05	30.7
WP_143604965.1\|11521053_11522202_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604966.1\|11522538_11522796_+	hypothetical protein	NA	NA	NA	NA
WP_143605870.1\|11522804_11523173_+	hypothetical protein	NA	NA	NA	NA
WP_143604967.1\|11524019_11524709_-	DUF1524 domain-containing protein	NA	NA	NA	NA
WP_143604968.1\|11525301_11526498_+	sialidase	E5ERA2	Bathycoccus_sp._RCC1105_virus	4.0e-14	28.4
WP_143604969.1\|11526630_11527827_+	chromosome condensation regulator RCC1	E5ERA2	Bathycoccus_sp._RCC1105_virus	6.4e-12	29.0
WP_143604970.1\|11527880_11528348_+	hypothetical protein	NA	NA	NA	NA
WP_143604971.1\|11528344_11529196_+	hypothetical protein	NA	NA	NA	NA
WP_143604972.1\|11529238_11530528_+	hypothetical protein	NA	NA	NA	NA
WP_143604973.1\|11530698_11531223_-	hypothetical protein	NA	NA	NA	NA
WP_143604974.1\|11532154_11532682_+	hypothetical protein	NA	NA	NA	NA
WP_143604975.1\|11533754_11534747_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143604976.1\|11536147_11536435_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_14

11573511 : 11619043

Saccharomonospora_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143604998.1\|11573511_11574759_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	I4AZM3	Saccharomonospora_phage	5.2e-81	53.5
WP_143604999.1\|11574730_11575342_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_143605000.1\|11575806_11576484_-	FCD domain-containing protein	NA	NA	NA	NA
WP_143605001.1\|11576470_11577022_-	VOC family protein	NA	NA	NA	NA
WP_143605002.1\|11577185_11579372_+	MFS transporter	NA	NA	NA	NA
WP_143605003.1\|11579414_11580773_+	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_143599674.1\|11583055_11583598_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_143605004.1\|11583803_11584856_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_143605005.1\|11585513_11586749_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_143605006.1\|11586757_11587636_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_143605007.1\|11587632_11588670_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_143605008.1\|11588666_11589398_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.7e-11	22.8
WP_143605009.1\|11589400_11590123_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-10	26.7
WP_143605010.1\|11590439_11591864_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_143605011.1\|11591870_11592758_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_143605012.1\|11592754_11593795_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_143605013.1\|11594468_11596100_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_143605875.1\|11596171_11596816_+	isochorismatase family protein	NA	NA	NA	NA
WP_143605014.1\|11596981_11597227_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_143605876.1\|11597630_11598077_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_143605015.1\|11598664_11599957_+	M24 family metallopeptidase	NA	NA	NA	NA
WP_143605016.1\|11600147_11600825_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_143605017.1\|11601103_11601649_-	flavin reductase family protein	NA	NA	NA	NA
WP_143605018.1\|11602226_11603216_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_143605019.1\|11603223_11604156_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_143605020.1\|11604128_11605013_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_143605877.1\|11605039_11605864_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.1e-29	34.6
WP_143605021.1\|11605870_11606968_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_143605022.1\|11607016_11607583_+	YceI family protein	NA	NA	NA	NA
WP_143605023.1\|11607603_11608410_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_143605024.1\|11608427_11608748_+	Dabb family protein	NA	NA	NA	NA
WP_143605025.1\|11608744_11609251_+	ester cyclase	NA	NA	NA	NA
WP_143605026.1\|11609538_11609958_-	hypothetical protein	NA	NA	NA	NA
WP_143605027.1\|11610001_11610622_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_143605028.1\|11611042_11611747_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_143605029.1\|11611866_11612289_-	SsgA family sporulation/cell division regulator	NA	NA	NA	NA
WP_143605030.1\|11612569_11612959_-	hypothetical protein	NA	NA	NA	NA
WP_143605878.1\|11613717_11614437_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	3.6e-26	30.2
WP_143605031.1\|11614566_11615112_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_143605032.1\|11615453_11615906_+	hypothetical protein	NA	NA	NA	NA
WP_143605033.1\|11616024_11616441_+	SsgA family sporulation/cell division regulator	NA	NA	NA	NA
WP_143605034.1\|11617433_11617862_-\|transposase	IS200/IS605 family transposase	I4AZM1	Saccharomonospora_phage	1.4e-41	62.1
WP_143605035.1\|11617885_11619043_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1P8DJA0	Virus_Rctr71	3.1e-72	43.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP041606

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041606_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041606_1

18606-18702

Orphan

Consensus_repeat	Method
CGCCGCTGCCGCGCTCTGGTCCGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041606_1

>merge|NZ_CP041606|1|18606-18702|CRISPRCasFinder
CGCCGCTGCCGCGCTCTGGTCCGTCGGGCCCGGCTGGGCAGGCACCGCCGGACGGCTGCCACCGAGGAACGCCGCCGCTGCCGCGCTCTGGTCAGTC

>NZ_CP041606|1|1|18606-18702|CRISPRCasFinder
CGCCGCTGCCGCGCTCTGGTCCGTC	GGGCCCGGCTGGGCAGGCACCGCCGGACGGCTGCCACCGAGGAACGC
CGCCGCTGCCGCGCTCTGGTCAGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041606.1\|WP_143599315.1\|12819_13131_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599447.1\|10130_11045_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367266
NZ_CP041606.1\|WP_143599325.1\|21621_24291_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223989
NZ_CP041606.1\|WP_143599327.1\|24859_25111_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599324.1\|21372_21573_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599319.1\|14792_15137_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599329.1\|25487_25796_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599313.1\|11891_12395_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599332.1\|26628_31089_+\|DUF3854-domain-containing-protein	unknown	unknown	gnl\|CDD\|225913
NZ_CP041606.1\|WP_143599318.1\|14437_14719_-\|ArsR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP041606.1\|WP_143599326.1\|24287_24863_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599321.1\|16448_17036_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599331.1\|26216_26699_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599330.1\|26010_26217_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP041606.1\|WP_143599316.1\|13149_13800_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|132997
NZ_CP041606.1\|WP_143599323.1\|20938_21340_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599320.1\|15146_15614_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599314.1\|12514_12823_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599328.1\|25107_25491_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041606.1\|WP_143599317.1\|13787_14441_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP041606.1\|WP_143599447.1\|10130_11045_-\|hypothetical-protein	gnl\|CDD\|367266	pfam02945, Endonuclease_7, Recombination endonuclease VII.	1.19568e-06
NZ_CP041606.1\|WP_143599330.1\|26010_26217_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	0.000238817
NZ_CP041606.1\|WP_143599316.1\|13149_13800_-\|glycosyltransferase	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	9.15238e-13
NZ_CP041606.1\|WP_143599318.1\|14437_14719_-\|ArsR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	0.00036301
NZ_CP041606.1\|WP_143599332.1\|26628_31089_+\|DUF3854-domain-containing-protein	gnl\|CDD\|225913	COG3378, COG3378, Phage associated DNA primase [General function prediction only].	4.04026e-51
NZ_CP041606.1\|WP_143599325.1\|21621_24291_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	6.21823e-51

>NZ_CP041606.1|WP_143599321.1|16448_17036_-|hypothetical-protein
MTTAPQTDPFSADAAAAAHFLGGGTVAAKWPTPGSVVEGTILSFRMGQQTDMESGELLFWEGKERVEQSKLKFPATAKPVEQLIIETQGEPTGITWETNRYVEKQLPDDDGVRTWYIKGALAAAVGKALRDASVRAPEIGGYIRAERGQDTKRPGSKYFSYTFAAKYTKAEANGEQAAGFLAQGDGGEAPDPFGG
>NZ_CP041606.1|WP_143599320.1|15146_15614_-|hypothetical-protein
MTSPMPLPGREAVGKPGTWTITNEYGESITVTGELLGLGSTYRPRHQNHPTTEYAPQRTHCSTCRWTEIRIFGTDPADGKALGQYLFLKRGASIVPEEKDFIEWEWLLTGHEVLEKLTTRRGSDVFLTPTASRTLSQAAEYDAGVRDAWLTRTVK
>NZ_CP041606.1|WP_143599319.1|14792_15137_-|hypothetical-protein
MLPQVADTVLGRRGPEDGTDDMGKHCAERLPFRGLRGHYTRLLQAYGRLLRDHRKLEAEHRDLLLRLPEPQPSTEVELWRPMRQTAWGAAREAMDVEAACELVRDTGLLTSAGG
>NZ_CP041606.1|WP_143599318.1|14437_14719_-|ArsR-family-transcriptional-regulator
MTTMTESVYGDSSQVRGRPRPAETRRRDETILALLRDNPGGLMRNDIAEMMGLNKSKTYLSLDRLRKQGLAEKTSPETSQADKDTLWVATGES
>NZ_CP041606.1|WP_143599317.1|13787_14441_-|hypothetical-protein
MMQQPGNAARDDEPVSSGDAGDAGSVVSGGYGIMQVIPPSVDHERLGEAISEFARRRTDLTGIGQMVLENYRWRGHGVRVGIDPSTDAGVFTDRVTGATFPEDEGQTFSDRFTGEMATGRSASDGLYARAVADLYGIPAGALFTEADVARLYAQSCMTESELRRELGLAPDLDANEELIRSTRAEFAQDPHDYDMPLEDGMRWSPPSEGEETPSCPA
>NZ_CP041606.1|WP_143599316.1|13149_13800_-|glycosyltransferase
MPRLTVAVVIPTIPGREEMLERALASVRAQTRRPDQVVVERDSLRTGADQARNRALERVTTDVIAWLDDDDVLRETHIRRCMRVLEQSPDKPDLVYPRPAVVGGQDPTAVSVQGQWVSPWGVRFGPEQEAHLRRFGSFIPMTHLVRTDMVRRIGGFRPGLDVTTEGIGRRYRGEDEDYLVRLLDAGARFEHLDAKTWTWNVHAGNTGGKGLASMTT
>NZ_CP041606.1|WP_143599315.1|12819_13131_-|hypothetical-protein
MTPTTATTGSPVAPGDGLTVRQRVSPSHASLETCVRERIGYLHDRGTRTFILDDFTRTAEQAGRPLSWIGDHLIVLEGLGVLRSVSDEGARAWRVNSGSGYLR
>NZ_CP041606.1|WP_143599314.1|12514_12823_-|hypothetical-protein
MTGPRTYGYVYGGTVVFSGRTREIEGSAWAHGRCDEVRLRAAAVQDLSRTENVPLAGIEITDFWYSELVTDDGVQHPCVDPFSPRGAPEPVDPFSPHDVPDK
>NZ_CP041606.1|WP_143599313.1|11891_12395_-|hypothetical-protein
MDKPELTIAESSAVNALLEVIGDNPLEARRFIAALSFRERTLLIAWARELERLGQQGQADYENRERSAWRAAEKPMTSYERGNLDTVVRDHLRARVTSGSDWTDVRDLVLLAAPHTDAGTKAVRDWAEGKIRDLVQSGHLSADGAEPGEYLVLSAPGQDKSGSAPAV
>NZ_CP041606.1|WP_143599447.1|10130_11045_-|hypothetical-protein
MDDGSRFRSGRKRKDRKPEARGPKGRDRKPEARAFGRRDDVRRRPAFARTPGVGRPFEAGGRRESGPGEPGPDRTGTLGGAGAGRRHRLRRQHPRAPLGAAQHGGERIVTVPYRYIKGAAAGRDETCVRCGSRRTDLVVDHCHVHGYSRGLLCGSCNSRLAVLDAGTAVPTPKEAFYLGNCPECRKAESLDSPHAFALRIGAVALAVASALDLSPRQAAALALALAEDERRETPERKAPGREPESGRQEHLSLKALAGESLTAAVRELRKAGRTENEIKTIVPTLPGHEGVKPDSLKKAIARTR
>NZ_CP041606.1|WP_143599323.1|20938_21340_-|hypothetical-protein
MEETRLRAVIREEIALAMKALKEAADRADMPYETGELESSALRAIGNAVDCFHTEYKAMCEWTDGERKRLTDPFTGEAPDVASCDHFYPRNPDGTWSNTCKNCGAGQPHKHEYAWVREAGQMCCVHCERPEPE
>NZ_CP041606.1|WP_143599324.1|21372_21573_-|hypothetical-protein
MSGQVFVQVRCDAEPDGPQAPPCMTPAALPDVTTLRALRTQLRSNGWHHMRSGRDICPLCWAGGHR
>NZ_CP041606.1|WP_143599325.1|21621_24291_-|DEAD/DEAH-box-helicase
MSQTLTLREYQREAIDAVQAAWAEGMQRPAVVLPTGAGKGHPLDTEIPTPDGLRKWGDLQPGDLVFGSNGCPTEVTDVYDRGVLPAFRVTFSDGSSVITDAEHLWTVRDYAHRRTSKEVRTLSTADIASLGLRYERSNRWAVPVSGTVTPDVDLPVGPYTLGSLIANGYLAHTSPMLTTPDEHVAERVSTEHEVTRAHVDETRYCPRFVVRGIQRHIRSMGLGVVSADKFIPRRYLEAGTAQRVALLQGLMDNDGSSRDERRSVLYHTTSPQLAEDVRELVCSLGGTATVGSSERVQPSNGKAYESLTVRILMPSDVPAISTPRKTRTNGPRRTFEPRRTIVAVERVEDQEIRCIRVAAPDSLYQVTRHHIVTHNTVVFSRMAAEHIAEHGTRVVILVHRDELADQTLSKLKQTEPGLFIGKVKAADDNIAADVMVCSVQTLARETRFNRLLDSQKTCGKVGLVIVDECHHASAKSYVSILAGLGCYSGMDVAEGEDDPTRAAGFTATLARGDGQGLGDVWEDAVYTRSPLWMMSRGHLVDVKSKIIDVDTLHLGDVKRSKGDYQAKDLGDAMMEAGGPQIIHKVLEEHAADRRSPIVFTPTVEVARATAEALPDAAYVHGGTPREERLNIYRKFRTGEVRTLVNCMVLTEGADFPHSDCAVIARPTKSQPLFIQMVGRVLRPSPATGKSDALVLILAGEGGSLCTLVDLEPGLEGKVVEDGETLAEAYEREESRKESKVPAGSLRFELKHRDIDLFKASAAYSWLRTNAGVQFIPLGDSGEIVIWPSKGGEEKWDVAYAPPRGTWERLHEGLDLGMAMAWAETEASDRSSLNMTKSASWRKKPASTKLVGLLRYAGKEVPEGIRAGLASDLFAVTIASRKLDRFVPRS
>NZ_CP041606.1|WP_143599326.1|24287_24863_-|hypothetical-protein
MSGTDELYRVLYTDHDGHEQVTGAMTRVQAYSRARDLAAKNYAVGSVMTASAAEDYMQDRYSPTYRGVEVPDDLRADGVPRSVYEAWKRGVDVTLDSEQPEPADADPFAPDLTMSREVADFILRATNGLLLEGYWPKDFRVGGRHGGDDTEDYDGDLVRKAADVISRDKIKNSELRRYIAELDADAEGGAS
>NZ_CP041606.1|WP_143599327.1|24859_25111_-|hypothetical-protein
MSGTDEQTSRVTAECNGICLSASDIGVGEYGDMIAYAHPDCPEHGDPLEDDPAAEICGGGDESQRYVREEDVRGVDTTLEAEQ
>NZ_CP041606.1|WP_143599328.1|25107_25491_-|hypothetical-protein
MSADDNDRALVVFLDGQDPVALARLKALVDARTRKPVPPPTNGPTTYRGIPVPGVLHHNWDQPEAAWWRQGVKAALDIAVPLLDELHNDEPCVLDHHGYCQMHGLPQPGPCPDGEIQEFIKEARNEG
>NZ_CP041606.1|WP_143599329.1|25487_25796_-|hypothetical-protein
MTKEQVAYAAMLNWLGSGVPDPARDAELIETLGREHRAAEHSAGPCVDCPHCWFTVRYAGPADDEHYAGLAVHLTGRHGLDAWTADAEATDAWRHPVLVMAA
>NZ_CP041606.1|WP_143599330.1|26010_26217_+|helix-turn-helix-domain-containing-protein
MEGFLTVAQVAGRAGVHTGSVYRWLDDPDVPLTRHRAGNGRVWIPEAEADAWIATRNTLTVVPAPKAS
>NZ_CP041606.1|WP_143599331.1|26216_26699_+|hypothetical-protein
MGAPVIKAIETKVNGCVFRSRTEARFSIFLQHAGVPWEFEPEGYKLRSGWYLPDFRIRPDWAPDQAWVEIKPPSDTFDDPRWAELAEGSGEMVLVLRGLHRRNDSCGRDHMVRIWHPTGVVADVPKLWTGARFAPAWDAASAARFDSRRPAGRKGRRRPS
>NZ_CP041606.1|WP_143599332.1|26628_31089_+|DUF3854-domain-containing-protein
MPPRRPGSTVGARPAGRGGDDHRDHAPGDQGITDQGSRKHMTTYVDTNQGRVSDHHSAELDASEISPEVRGARGYETLYGTDEDRARLRQESIPVWAWREESAFPGLLIPLYRVTGERIGAQFKPGQPQPHGEKLMKYASPVGTRPRLDVPPAMADSVRTVTSALWITEGVKKADAIASKGIPVVSLSGVFNWRSRLGTLGDWEDIPLKGRTVLICFDSDAKHNRMVLMAMRRLGMWLESKGAAAIHYLIVPEEVNGAPVKGVDDYFHAGGTLESLRDVATTEMPSDNTRDAAFSDAVLADTVCSEALDGSYRWAYGLGWMRWTGKVWRECPEPVVLEEIRQWALAGFQRVLDRQRAEPNKDLRAEMDGWRSALSASKLSNLLKLSRGTLVTHADEMDSDPDALNCQNGILDLRTGVLTPHDPDRLMTKITAADYVPATFHPDWKQALEAIPEAVCEWFQLRMGQGITGHIPPDDLILILQGGGSNGKSTVVDAIARAIGEKDGYHTVVSHRALLGNASDNHPTEMMDFMGARLAVLEETPEAKKLDVNRAKELAGTKAIKARRMRQDPVTFTTSHTLVINTNHRPLVEESDHGTWRRLAMLCFPYTFRKPGEACTGPNDRPGDATLRQRLATDERVPAAVLAWVVEGARKWYAADMIMPPPPKEVEDATLEWRKESDLILSFIGDVLEFDWNSHVYAPELRETFNKYLADKGHREWTERTFVARFGSHDECARNGVARKRIKTRDGRSTLVPLASVPNPYYAWLGVRFQDPDENPQVNEGEDNPVPPVPSTTYNREIGSRIGGTELQGTGGTGPGTHPDADPFGDDPFGETEADHAPVATVPAPAPVPAAETVQRAGGQIGIDIESHSAKRLFTHTDLGGDPYTKLSGYVTEDGTEVVVNSVAELIKRLEDADEIYGHNLLGFDLMALARHHGADYDKLAAKTVDTLRWAQTEDPPGAAHEKPWATKGYYGLDGLAARLGMPGKTDDLKGLALKHAPEEIDGRKLTEAERLEIGFGRIPADDPEYRSYFSGDLKATRGVRRALGEPTDYVRREMRVAHIQHRPTLTGWKVDVPVLRELADAEADKKRQSLEWLHENCGVPLTKEVSRGRGKNKVTTEESVLSPLSTTVGREAVIKAFADRGAAFYPKTASGLISLNKDALGETSYFVGKGAGARQVPAMLNPNVLRTFAERGADVDALREMCGHIVTVTSSVQKYREIMDHLVGDRIHPQVGDLQGSGRWAYVRPSVTNMAKRGGKVAQRRPLIADDGSLLICFDLDQVDMRAIAGHCQDPAYMQNFAPGADAHSMIADAVFGRHDGEWRDNAKRIGHGWNYGMSVKGIANSGVEMELAQKFDDQMNAQYPGLCAWRSEVRERGAAGELLDNGFGRKMRCNPDRAWTQAPALMGQGGARDIMCSALLRLVDMIPEATEWLRCVVHDEVVLCVPEHMAQGVTEAVLEAFTFTFKGVPITAGASKAARDWASCYSKD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP041606_1	1.1\|18631\|47\|NZ_CP041606\|CRISPRCasFinder	18631-18677	47	NZ_CP041606	Streptomyces sp. S1D4-14 plasmid pS1D4-14.2, complete sequence	18631-18677	0	1.0

1. spacer 1.1|18631|47|NZ_CP041606|CRISPRCasFinder matches to NZ_CP041606 (Streptomyces sp. S1D4-14 plasmid pS1D4-14.2, complete sequence) position: , mismatch: 0, identity: 1.0

gggcccggctgggcaggcaccgccggacggctgccaccgaggaacgc	CRISPR spacer
gggcccggctgggcaggcaccgccggacggctgccaccgaggaacgc	Protospacer
***********************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17450 : 31089

Streptomyces_phage(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143599322.1\|17450_20864_-	hypothetical protein	A0A0S2MU09	Streptomyces_phage	2.1e-31	33.3
WP_143599323.1\|20938_21340_-	hypothetical protein	NA	NA	NA	NA
WP_143599324.1\|21372_21573_-	hypothetical protein	NA	NA	NA	NA
WP_143599325.1\|21621_24291_-	DEAD/DEAH box helicase	A0A2D1GP10	Streptomyces_phage	3.8e-04	69.7
WP_143599326.1\|24287_24863_-	hypothetical protein	NA	NA	NA	NA
WP_143599327.1\|24859_25111_-	hypothetical protein	A0A1P8VW04	Streptomyces_phage	1.8e-09	55.9
WP_143599328.1\|25107_25491_-	hypothetical protein	NA	NA	NA	NA
WP_143599329.1\|25487_25796_-	hypothetical protein	NA	NA	NA	NA
WP_143599330.1\|26010_26217_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_143599331.1\|26216_26699_+	hypothetical protein	A0A2I4R669	Erysipelothrix_phage	1.0e-08	58.8
WP_143599332.1\|26628_31089_+	DUF3854 domain-containing protein	Q6J7X6	Actinoplanes_phage	6.6e-86	35.3

DBSCAN-SWA_2

34274 : 39141

Arthrobacter_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143599340.1\|34274_34949_+	hypothetical protein	A0A222ZI71	Arthrobacter_phage	1.1e-13	33.3
WP_143599341.1\|34948_35494_+	hypothetical protein	A0A222YVI0	Streptomyces_phage	1.5e-19	40.6
WP_143599342.1\|35490_35760_+	hypothetical protein	A0A2I6PG53	Plesiomonas_phage	1.6e-08	46.2
WP_143599343.1\|35873_36416_+	hypothetical protein	A0A0R8V9Z3	Thermobifida_phage	1.3e-07	39.3
WP_143599344.1\|36415_36643_+	hypothetical protein	NA	NA	NA	NA
WP_143599345.1\|36639_36957_+	hypothetical protein	NA	NA	NA	NA
WP_143599346.1\|36970_37828_+	hypothetical protein	A0A0K0N7E2	Gordonia_phage	2.3e-35	38.9
WP_143599347.1\|38094_39141_+	NAD-dependent epimerase/dehydratase family protein	E3SJ76	Synechococcus_phage	1.0e-66	39.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage