CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP034442	Streptococcus oralis subsp. dentisani strain F0392 chromosome, complete genome	2 crisprs	csa3,DEDDh,DinG,cas3	1	1	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP034442_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP034442_1

548318-548400

Orphan

Consensus_repeat	Method
TTCTGGTGTCTGCCACCGCTTGGCCCTTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP034442_1

>merge|NZ_CP034442|1|548318-548400|CRISPRCasFinder
TTCTGGTGTCTGCCACCGCTTGGCCCTTACGTCCAAGATTGCTATCGGATTTCGTTCTGGTGTCCGCCACCGCTTGGCCCTTA

>NZ_CP034442|1|1|548318-548400|CRISPRCasFinder
TTCTGGTGTCTGCCACCGCTTGGCCCTTA	CGTCCAAGATTGCTATCGGATTTCG
TTCTGGTGTCCGCCACCGCTTGGCCCTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP034442.1\|WP_000840776.1\|558752_558986_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_004246150.1\|555174_557052_-\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|367119
NZ_CP034442.1\|WP_000401894.1\|530760_531846_-\|DUF3991-domain-containing-protein	unknown	unknown	gnl\|CDD\|379044
NZ_CP034442.1\|WP_004246112.1\|532656_532854_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_001097585.1\|553627_553987_-\|PrgI-family-protein	unknown	unknown	gnl\|CDD\|378907
NZ_CP034442.1\|WP_143888987.1\|540111_546171_-\|leucine-rich-repeat-protein	unknown	unknown	gnl\|CDD\|372554
NZ_CP034442.1\|WP_000387506.1\|539508_539919_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000933089.1\|531855_532497_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000627866.1\|554911_555154_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000869753.1\|557529_557829_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000821297.1\|558162_558750_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP034442.1\|WP_000566547.1\|558998_559379_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224311
NZ_CP034442.1\|WP_000998892.1\|532867_533164_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000093677.1\|557051_557540_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_141561219.1\|547083_548181_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP034442.1\|WP_000159218.1\|530096_530480_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000969635.1\|533177_533462_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP034442.1\|WP_000653452.1\|548494_551308_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090
NZ_CP034442.1\|WP_001054258.1\|554040_554895_-\|conjugal-transfer-protein-TrbL	unknown	unknown	unknown
NZ_CP034442.1\|WP_000152426.1\|530476_530710_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP034442.1\|WP_000566547.1\|558998_559379_-\|hypothetical-protein	gnl\|CDD\|224311	COG1393, ArsC, Arsenate reductase and related proteins, glutaredoxin family [Inorganic ion transport and metabolism].	1.2072e-20
NZ_CP034442.1\|WP_001097585.1\|553627_553987_-\|PrgI-family-protein	gnl\|CDD\|378907	pfam12666, PrgI, PrgI family protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 116 and 146 amino acids in length. This protein is found in an operon that is part of a Type IV secretion system.	4.91792e-15
NZ_CP034442.1\|WP_000401894.1\|530760_531846_-\|DUF3991-domain-containing-protein	gnl\|CDD\|379044	pfam13155, Toprim_2, Toprim-like. This is a family or Toprim-like proteins.	0.000524347
NZ_CP034442.1\|WP_141561219.1\|547083_548181_-\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	1.48135e-163
NZ_CP034442.1\|WP_004246150.1\|555174_557052_-\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|367119	pfam02534, T4SS-DNA_transf, Type IV secretory system Conjugative DNA transfer. These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.	1.20177e-59
NZ_CP034442.1\|WP_143888987.1\|540111_546171_-\|leucine-rich-repeat-protein	gnl\|CDD\|372554	pfam13306, LRR_5, Leucine rich repeats (6 copies). This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.	1.73136e-35
NZ_CP034442.1\|WP_000653452.1\|548494_551308_-\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	3.93521e-36
NZ_CP034442.1\|WP_000821297.1\|558162_558750_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.05036e-07

>NZ_CP034442.1|WP_141561219.1|547083_548181_-|IS256-family-transposase
MQHITRKRFIPMTQFTTELLNFLAKKQDIDEFFRSSLETAMNDLLQAELSAFLEYEPYDKVGYNSGNSRNGTYSRKFETKYGTVQLSIPRDRNGNFSPALIPAYGRRDDHLEKMVIKLYQTGVTTREISDIIEQMYGHHYSPTTISNISKATQENVATFHERSLEANYSVLFLDGTYLPLRRGTVSKECIHIALGITPEGQKAVLGYEIAPNENNASWSNLLDKLQNQGIQQVSLVVTNGFKGLEQMISQAYPLAKQQRCLIHISRNLASKVKRSDRAVILEQFKMIYRAENLEMAVQALEDFIAEWKPKYKKIMESLENTDNLLTFYQFPYKIWHSIYSTNLIESLNKEIKRDCGCNRGKNQSS
>NZ_CP034442.1|WP_143888987.1|540111_546171_-|leucine-rich-repeat-protein
MKEVLKLRKRRTGQWVTVAGMVLIGACMTIGNTVVFADDTQTYPIEVSDSNKFNLTDSPSPLSSENLGTNNRGHEVATLPSTGHVDSSAKTTPEYLMSESSTVSLVKSDVATTETSTSVLASLSEVAPTKSTDSSETLVPSTLSEDPKHASTSEGAAAEVKSHSETLVEHSTNSNNEEESGDNLIYDIHNQEVTITDIKRKETIKKLIIPQRISNYRVTEIGSSAFSGSSLKEVVLPSTLTQIGSSAFSGTQLKDITLPTSVTTIGSGAFGSIDSLSSVVIPKNLSNAYRAFEGSQHLKTIHFEEGITKIADGLFKDSGISSITIPKTVTEIGYEAFRNTRITELYIPDSVTKLGANSFGTDYYNDFKTLTKVSLPSELQSTSSPFYGQKNLKEVVLRGNWKTIPGGLFSGTGIEKLVIPEGVTEIGADAFSGSSLKEVVLPKTLTKIGDSAFSGTQLTNMSVPSSVREIGSYAFNSTPLEVINLPYGLQVIGSGAFRNTKLETIEIPEGVTYLDDYTLANIPTLKSVYLPKSLTAFVQSWNTPSESVEYHVYLDSFALEYMIEKQLNFKLRDENVANDDSKVLDSSNSYYLTTTTGTRRQGYLGLDLKYAIKKDKSSDDGKYVLHLNIPSTTKVFESKIRVNGQDVTATVSNGYLDIPVSEEIGKIKLMLMTENRELTNVRLFAQFSYQKDRKKVSENIGAINVNIPVLTLTANQVTSRSYSRISGIADPNDQLIAYLDDMVVGQVKIKKDGSYTFDVPLVTPVDNKEYTIKVKALSSDGREISETTTVRYEKNYPELVNFIMRHNGYTYNLKENQDKVPVISFRPGGKFDFEVEYTNTEQIENIYLVSVREGIKKYVQLYYDENLKKYIYHGYFDEKNTSYVPGKLELQIINKEKRIPSILIELEGKKIDYLSSDFKEKYKIIDELNRDKFVTRIINRETQKVVLTEEISIDILKELFDNIQNNSESQPKTSSILVKEEENNLGFRSAEGTKGEPILNLFYALLLEGAGNINLNQFFSPAKFALEELFKIPELIFRKYAGLSKDLSTVSDSVFDGIVDKQLGNKAIKDEFAKVPGLEKVVNNIGLYQELGTFVMKWSMLELLEQLLENPKLVIQGNYKYNALQTIKREKNNFINASTLSIGVSLASNSKHVALGALIYDFGATFYNFIRGIGGKLEKWERIPTVSGLPESIYENIIDDLKIGAPTLTNWKVKTPSNNTKEEDIGTKAYSNSFDVSNLFSVRYTTPHNNLSRFTTFNIPAFQFVVDPSGIVINNVSKKPVTGATINLYYQGENGEEILWDAGEYSQFNPLLTTVNGEYAWDVPEGFWKVKVSKEGYESAESDWLPVPPPQTEVHFNLKPLSYKIAYKVGDGILKEDVPRSYQTDVDTELPYPVRKGYVFTGWYLDDNFSGEPFFNTLFDKAGDKVLYAKWEKDTKILSDDDNVVTVTVSGNDVNVIGKVVKKEVTNADILEKVGDHNNLLMEIQALDDDGNVVSLSEDAEIELAVISGQKPYKVLHYVKDKSTFEEVPFNWNEKDKNISLTTSTLGVYLIQNKLTEKQMTSKVRQESRVLKTDKIEYVDDSSLDAGKVREVAAINGKVLVEITDVYVNGELQSSTEKELSRIEPQAKKVYRGTKQVSHVPDVAPMENNKPEAIIETKVRQESRVLKTDKIEYVDDSSLDAGKVREVAAINGKVLVEITDVYVNGELQSSTEKELSRIEPQAKKVYRGTKQVSHVPDVAPMENNKPEAIIETKVRQESRVLKTDKIEYVDDSSLDAGKVREVAAINGKVLVEITDVYVNGELQSSTERELSRIEPQAKKVYRGTKQVSHVPDVAPMENNKPEAIIETKVRQESRVLKTDKIEYVDDSSLDAGKVREVAAINGKVLIEITDIYVNSELQLSTERELSRIEPQAKKVYRGTKWVSQVPDVAPIEVNRIERNNITKEHPGVSIAINTKLEPVVMNQSSSEPLSSKETTIRTKGYLPNTSSEYSYGFELAGIIALATAHFGIISNKRKKNIKN
>NZ_CP034442.1|WP_000387506.1|539508_539919_-|hypothetical-protein
MEAIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEIEEGTNPLEKDLQDIDQTSIIEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENQQNLEDLYTYYMRTDAVSLLSSDLEISPQEVEMEIEL
>NZ_CP034442.1|WP_000969635.1|533177_533462_-|hypothetical-protein
MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSIRELTSQLEIALQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID
>NZ_CP034442.1|WP_000998892.1|532867_533164_-|hypothetical-protein
MNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFISFLIFVEVYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFFNFINNKKM
>NZ_CP034442.1|WP_004246112.1|532656_532854_+|hypothetical-protein
MNKLKEENLRRALSHIERHRQAINTGNNSEDNDFHKLLLQFSYEVYERIKANKKPYPNLDSDKVF
>NZ_CP034442.1|WP_000933089.1|531855_532497_-|hypothetical-protein
MLNKVKTKALISVGAVAATSFILMMGYTVGQHSTAKQSRKEIELAAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNLTYVSDLKNANQSKTNQTETRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSIPSLPNTTTK
>NZ_CP034442.1|WP_000401894.1|530760_531846_-|DUF3991-domain-containing-protein
MEIEECKQISILDVANRLGISFKQVSNGVYEHSEHDSFRIFSTTNTFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPFQKEAVQEKRERPFYYPLKSVEDSNCSLARYYLTEYRGISEENIQKMIQQGLIAQASWKTNETVEPVIVFKSYDHRHKLQAASLQGIYKNHSLPRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELHQQNLSDVRLVSMEGLKRSVVAYQTLRLIADENQKLEFLDTVIPSKLFPLINTIRDTTSYFDNHPDLFTLAVDCDDAGKDFSDKLSQSGFPVLLDLPDNESGKEKRDWNDILREKKSDLQLMIETTKETLRNQPVRQTSQCLEL
>NZ_CP034442.1|WP_000152426.1|530476_530710_-|hypothetical-protein
MTIIERLEEKVTRQESKVARETEKLATYKEQLETAMFATFKRRQSISHMSFEEALDHAFGKERQFDDSEFRKDEMSE
>NZ_CP034442.1|WP_000159218.1|530096_530480_-|hypothetical-protein
MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNEVNYEAAFQKRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEELHTLIDTKNKDNKKLQSIYDAISELH
>NZ_CP034442.1|WP_000653452.1|548494_551308_-|CHAP-domain-containing-protein
MKDKREIIRARKAFRRSLKDEKKFLKQEKKEVRKQKKDSAVLDEKAWKKEIKQNLEEMREASKARVKQANEDYNHILQNSPPSLLNRKELRGRRLPHARKRLKIAKEQFKKAKAQSKEERKESRKERKTNQKFLYGQESKHKSNFFFQGKSLEELKAKKEVKAAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELTSENEDLEGYRTLQETIRKGKRYSRLSYNIGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNRFRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPVTWIVGGIVFLLLLMMSFFLGFSSASLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKIDDVMGYMNFKFHDYELHKPVHLFSSKTYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSRDDQEEIKELKEEGMYASMQELDNPFEGKSNEDNLTMTYRYGYYDLDGKPTLQEYILLESKAHQTIVAPMDGVVSLDGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKNKKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAAILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGLGLGQWTDTADGSTRHTALLNYARTQNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFGNTGSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIKKGFSQTNGGQAKSDPQSLEGVRGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDWVATASSLGGETGSIPRVGAIVSFVGGTHGTPADYGHVAFVEKVYDDGSFLVSETNYGGNPNYTFRKISQADSAISFAYTTK
>NZ_CP034442.1|WP_001097585.1|553627_553987_-|PrgI-family-protein
MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLFFSQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGPEHEKKIKYIKETKNFND
>NZ_CP034442.1|WP_001054258.1|554040_554895_-|conjugal-transfer-protein-TrbL
MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYNPTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYIMVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFFALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMVYAVQGVLIFMIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLIQAILLIIALVGSQRTARSILGM
>NZ_CP034442.1|WP_000627866.1|554911_555154_-|hypothetical-protein
MITHFKGFVYGVDASAMFAQAMYLLQKGLIAVGAFLVVVGIVNLATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI
>NZ_CP034442.1|WP_004246150.1|555174_557052_-|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLMEGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTLKEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNLIQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLNRMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQTEYQNLLKCQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYGKKYGTENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKSMVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIPDFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFKFMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANMPVFKSKKYNSTKHPNWKYLANQETDERWWNYQINPLNQRQENHLEGLRIRDLTFESSLK
>NZ_CP034442.1|WP_000093677.1|557051_557540_-|hypothetical-protein
MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYKIGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFYTKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEMVR
>NZ_CP034442.1|WP_000869753.1|557529_557829_-|hypothetical-protein
MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL
>NZ_CP034442.1|WP_000821297.1|558162_558750_-|CPBP-family-intramembrane-metalloprotease
MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYCGSLISFLWMYGQRKQVVKVNMKIRIKWLGIGFVSLLIISLCFSLIHAQGTTNQVNLIGLQHQVPWFSFLLFLINASMVEEFLYREILWNLVRKLDIRIALTSVLFALAHHPGTILAWFLYVSLGMFLGMVRYKSDFLGSMGLHLVWNLLVYSLLLF
>NZ_CP034442.1|WP_000840776.1|558752_558986_-|hypothetical-protein
MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQKIRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR
>NZ_CP034442.1|WP_000566547.1|558998_559379_-|hypothetical-protein
MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMMSYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLEEARALLPRDTKQLIYMEQTHYLSS

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP034442_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP034442_2

967122-967475

Orphan

Consensus_repeat	Method
TGGTGCCGGCTTCGGCGCNGGTTTTGGTGC	CRT

6 spacers

The CRISPR arrays of NZ_CP034442_2

>merge|NZ_CP034442|2|967122-967475|CRT
TGGTGCCGGCTTCGGCGCGGGTTTTGGTGCTGGCTTTGGAGCGGGTTTCGGTGCTGGCTTCGGCGTAGGTTTTGGTGCTGGCTTCGGCGCAGGTTTTGGTGCCGGCTTCGGCGCAGGTTTTGGTGCCGGCTTCGGCGCAGGTTTTGGTGCCGGCTTCGGCGCGGGTTTTAGTGCCGGCTTCGGCGCGGGTTTTGGTGCTGGCTTCGGCGCGGGTTTTGGTGCTGGCTTCGGTGCGGGTTTCGGTGCCGGCTTCGGCGCGGGTTTCGGTGTAGGTTTTGGTGCCGGCTTCGGCGCAGGTTTTGGTGCTGGCTTCGACGCGGGTTTTGGTGCCGGCTTCGGCGCGGGTTTTGGTGC

>NZ_CP034442|2|1|967122-967475|CRT
TGGTGCCGGCTTCGGCGCGGGTTTTGGTGC	TGGCTTTGGAGCGGGTTT
CGGTGCTGGCTTCGGCGTAGGTTTTGGTGC	TGGCTTCGGCGCAGGTTT
TGGTGCCGGCTTCGGCGCAGGTTTTGGTGC	CGGCTTCGGCGCAGGTTTTGGTGCCGGCTTCGGCGCGGGTTT
TAGTGCCGGCTTCGGCGCGGGTTTTGGTGC	TGGCTTCGGCGCGGGTTT
TGGTGCTGGCTTCGGTGCGGGTTTCGGTGC	CGGCTTCGGCGCGGGTTTCGGTGTAGGTTT
TGGTGCCGGCTTCGGCGCAGGTTTTGGTGC	TGGCTTCGACGCGGGTTT
TGGTGCCGGCTTCGGCGCGGGTTTTGGTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP034442.1\|WP_000158623.1\|963357_964197_-\|thymidylate-synthase	unknown	unknown	gnl\|CDD\|234984
NZ_CP034442.1\|WP_000354320.1\|959348_960278_-\|ribonuclease-Z	unknown	unknown	gnl\|CDD\|274246
NZ_CP034442.1\|WP_000078548.1\|964776_965736_-\|ROK-family-glucokinase	unknown	unknown	gnl\|CDD\|273246
NZ_CP034442.1\|WP_000573208.1\|960908_962147_-\|GTPase-HflX	unknown	unknown	gnl\|CDD\|225171
NZ_CP034442.1\|WP_000274767.1\|977039_977780_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP034442.1\|WP_025168998.1\|978031_979372_+\|sodium-dependent-transporter	unknown	unknown	gnl\|CDD\|271367
NZ_CP034442.1\|WP_000136328.1\|983526_985770_-\|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP034442.1\|WP_001294298.1\|979411_980356_-\|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl\|CDD\|224399
NZ_CP034442.1\|WP_000129707.1\|960292_960916_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235382
NZ_CP034442.1\|WP_000554838.1\|967950_969666_-\|aminodeoxychorismate-synthase-component-I	unknown	unknown	gnl\|CDD\|273133
NZ_CP034442.1\|WP_001052648.1\|981079_981427_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319947
NZ_CP034442.1\|WP_001097949.1\|964248_964683_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236843
NZ_CP034442.1\|WP_000746261.1\|969732_976230_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|369436
NZ_CP034442.1\|WP_000410710.1\|951086_958328_-\|DUF4982-domain-containing-protein	unknown	unknown	gnl\|CDD\|225789
NZ_CP034442.1\|WP_001291473.1\|980613_980874_-\|membrane-protein	unknown	unknown	gnl\|CDD\|367325
NZ_CP034442.1\|WP_000850171.1\|962139_963024_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NZ_CP034442.1\|WP_001051782.1\|963144_963315_+\|DUF3042-family-protein	unknown	unknown	gnl\|CDD\|371431
NZ_CP034442.1\|WP_001259182.1\|958572_959328_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP034442.1\|WP_000191810.1\|981537_983313_-\|pyruvate-oxidase	unknown	unknown	gnl\|CDD\|213733
NZ_CP034442.1\|WP_000360266.1\|976232_976796_-\|TIGR01440-family-protein	unknown	unknown	gnl\|CDD\|237472

Protein	Function_ID	Function_description	E-value
NZ_CP034442.1\|WP_000158623.1\|963357_964197_-\|thymidylate-synthase	gnl\|CDD\|234984	PRK01827, thyA, thymidylate synthase; Reviewed.	9.35425e-114
NZ_CP034442.1\|WP_000354320.1\|959348_960278_-\|ribonuclease-Z	gnl\|CDD\|274246	TIGR02651, Ribonuclease_Z, ribonuclease Z. Processing of the 3-prime end of tRNA precursors may be the result of endonuclease or exonuclease activity, and differs in different species. Member of this family are ribonuclease Z, a tRNA 3-prime endonuclease that processes tRNAs to prepare for addition of CCA. In species where all tRNA sequences already have the CCA tail, such as E. coli, the need for such an enzyme is unclear. Protein similar to the E. coli enzyme, matched by TIGRFAMs model TIGR02649, are designated ribonuclease BN. [Transcription, RNA processing].	3.07231e-136
NZ_CP034442.1\|WP_000078548.1\|964776_965736_-\|ROK-family-glucokinase	gnl\|CDD\|273246	TIGR00744, Glucokinase_Glucose_kinase., ROK family protein (putative glucokinase). This model models one branch of the ROK superfamily of proteins. The three members of the seed alignment for this model all have experimental evidence for activity as glucokinase, but the set of related proteins is crowded with paralogs of different or unknown function. Proteins scoring above the trusted_cutoff will show strong similarity to at least one known glucokinase and may be designated as putative glucokinases. However, definitive identification of glucokinases should be done only with extreme caution. [Unknown function, General].	6.80956e-100
NZ_CP034442.1\|WP_000573208.1\|960908_962147_-\|GTPase-HflX	gnl\|CDD\|225171	COG2262, HflX, GTPases [General function prediction only].	0
NZ_CP034442.1\|WP_000274767.1\|977039_977780_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.59244e-43
NZ_CP034442.1\|WP_025168998.1\|978031_979372_+\|sodium-dependent-transporter	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	3.31814e-171
NZ_CP034442.1\|WP_000136328.1\|983526_985770_-\|heavy-metal-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP034442.1\|WP_001294298.1\|979411_980356_-\|mannose-6-phosphate-isomerase,-class-I	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	2.18349e-147
NZ_CP034442.1\|WP_000129707.1\|960292_960916_-\|hypothetical-protein	gnl\|CDD\|235382	PRK05270, PRK05270, UDP-glucose--hexose-1-phosphate uridylyltransferase.	2.26926e-13
NZ_CP034442.1\|WP_000554838.1\|967950_969666_-\|aminodeoxychorismate-synthase-component-I	gnl\|CDD\|273133	TIGR00553, Aminodeoxychorismate_synthase_component_1, aminodeoxychorismate synthase, component I, bacterial clade. Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	2.44805e-176
NZ_CP034442.1\|WP_001052648.1\|981079_981427_-\|hypothetical-protein	gnl\|CDD\|319947	cd08359, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	9.94534e-11
NZ_CP034442.1\|WP_001097949.1\|964248_964683_-\|hypothetical-protein	gnl\|CDD\|236843	PRK11092, PRK11092, bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase.	6.29176e-11
NZ_CP034442.1\|WP_000746261.1\|969732_976230_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|369436	pfam07580, Peptidase_M26_C, M26 IgA1-specific Metallo-endopeptidase C-terminal region. These peptidases, which cleave mammalian IgA, are found in Gram-positive bacteria. Often found associated with pfam00746, they may be attached to the cell wall.	0
NZ_CP034442.1\|WP_000410710.1\|951086_958328_-\|DUF4982-domain-containing-protein	gnl\|CDD\|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	0
NZ_CP034442.1\|WP_001291473.1\|980613_980874_-\|membrane-protein	gnl\|CDD\|367325	pfam03083, MtN3_slv, Sugar efflux transporter for intercellular exchange. This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organisims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.	0.000366792
NZ_CP034442.1\|WP_000850171.1\|962139_963024_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	2.79226e-142
NZ_CP034442.1\|WP_001051782.1\|963144_963315_+\|DUF3042-family-protein	gnl\|CDD\|371431	pfam11240, DUF3042, Protein of unknown function (DUF3042). This family of proteins with unknown function appears to be restricted to Firmicutes.	2.15745e-16
NZ_CP034442.1\|WP_001259182.1\|958572_959328_-\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	1.79926e-96
NZ_CP034442.1\|WP_000191810.1\|981537_983313_-\|pyruvate-oxidase	gnl\|CDD\|213733	TIGR02720, Pyruvate_oxidase, pyruvate oxidase. Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an enzyme with FAD and TPP as cofactors that catalyzes the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase [cytochrome] (EC 1.2.2.2) as in E. coli PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name. [Energy metabolism, Aerobic].	0
NZ_CP034442.1\|WP_000360266.1\|976232_976796_-\|TIGR01440-family-protein	gnl\|CDD\|237472	PRK13690, PRK13690, hypothetical protein; Provisional.	2.74062e-110

>NZ_CP034442.1|WP_000078548.1|964776_965736_-|ROK-family-glucokinase
MSQKIIGIDLGGTSIKFAILTQEGEIQEKWSIKTNILDEGSHIVDDMIESIQHRLDLLGLSATDFRGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKEKIEKALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGAAGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDDGEEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEFLLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ
>NZ_CP034442.1|WP_001097949.1|964248_964683_-|hypothetical-protein
MNTSKQPMLELALSIATEAHRGQFDKAGIDYIEHPIYVASQVDTEEEKAVALLHDVIEDSPFTAEELLLAGLLETVVTAVQILSKKKGQDYQTYLENVKSNPLARIVKLADLKHNSDLSRLSSVTDKDLERLEKYKKAIDYLSM
>NZ_CP034442.1|WP_000158623.1|963357_964197_-|thymidylate-synthase
MTKADTIFKENIERILKDGVFSEQARPKYKDGTVANSKYVTGAFAEYDLAMGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNSKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKILKQLEANPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKIGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYNPVKPQLKFDLAI
>NZ_CP034442.1|WP_001051782.1|963144_963315_+|DUF3042-family-protein
MAKGFAKGLVTGVAGTVAAVAGAVYAIKKKVIEPEEQKAAFIEENRKKAARRRVSH
>NZ_CP034442.1|WP_000850171.1|962139_963024_-|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MKTKIIVIVGPTAVGKTALAIEVAKRFGGEVVSGDSQQVYRGLDIGTAKASPEEQAVVPHHLIDVREVTESYSAFDFVSEAKAAIEDIQSRGKLAIIAGGTGLYIQSLLEGYHLGGETPHEEILAYRTSLEPYSDEELAHLVEQAGLEIPQFNRRRAMRALEIAHFGQDLENQESPYEPLIICLDDERSQLYERINRRVDLMFEAGLLDEAKWLFDHYPDVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIGEPDVQDRILSQIEEFLDD
>NZ_CP034442.1|WP_000573208.1|960908_962147_-|GTPase-HflX
MIETEKKEERVLLVGVELQGMDNFDLSMEELASLAKTAGAVVVDSYRQKREKYDSKTFVGSGKLEEIARMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVIDRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQLELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNTLTSKIQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESKHVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPRLTLYNKADLVEDFTPTQTPYALISAKSEDSRENLQALFLEKIKEIFEAFTLRVPFSKSYKIHDLESVAILEDRDYQDDGEVITGFISEKNKWRLEEFYD
>NZ_CP034442.1|WP_000129707.1|960292_960916_-|hypothetical-protein
MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLALITPPPSVVNAYFAELYQKKSPQAATDYFAELSQELNLYNAEPSFTFENKPFIRLNLSGKSFGFCYEREGLCRIFSEAEEAITDNLLFEIAQIFPHQLVFEESGKIYMKAVGDEEVVSVKNLTALTDLESLADGRKRLKGYSQEDLLQEAVAFSGSRYFRSENRTAMLYID
>NZ_CP034442.1|WP_000354320.1|959348_960278_-|ribonuclease-Z
MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQNRILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLDIYGPQGIKSFVLTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLEGTLDAEKLKAAGVPFGPLFGKIKNGQDVVLEDGTEIKATDYISAPRPGKIITILGDTRKTNASVRLGINADILVHESTYGKGDEKIARNHGHSTNMQAAQVAAEAGAKRLLLNHISARFLSKDISQLKKDAATVFENVHVVKDLEEVEI
>NZ_CP034442.1|WP_001259182.1|958572_959328_-|SDR-family-oxidoreductase
MRTILITGASGGLAQEMVKLLPDDQLILLGRNKEKLAQLYGNHPRVELIEIDITDDSVLEDLVADLYLRYGKIDVLINNAGYGIFEEFDQISDKDIHQMFEVNTFALMNLSRRIGFRMKKRRKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRLELMPYGVYLTTVNPGPIRTRFFDQADPDGSYLKSVDRFLLEPDAVAKKIVKTIGKNKRELNLPVLLNLAHKFYSLFPKLADKLAGGIFNYK
>NZ_CP034442.1|WP_000410710.1|951086_958328_-|DUF4982-domain-containing-protein
MEKGHWNRKRVYSIRKFAVGACSVMIGTCAVLFGGSVVEASPVLADETPIAHTVEQAKEESPAVEEKQDQAVAEKNVAASVEQSQAAPIEASKPEVKEDEAITQKEEKASSKPEENDPKVESQASSQEKPVKEDLKAATNEEVNQMIEDRKVNFNQNWHFKLNANSKEAVKPDADVSTWQKLDLPHDWSIFNDFDHQSPAQNEGGQLNGGEAWYRKTFKLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVIAVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEQQQHGKVETHVTSKIVNTDDKDHELVAEYQIVERGGQAVTGLVRTASRTLKAHESTSLDAILEVEKPKLWTVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLHHDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFDTWYGGKKPYDYGRFFEKDATHPEARKGEKWSDYDLRTMVERDKNNPAVFMWSIGNEIGEANGDAHSLATVKRLVKVIKDVDTTRYVTMGADKFRFGDGSGGHEKIAEELDAVGFNYSEDNYKKLRAKHPKWLIYGSETSSATRTRGSYYRPESELKHSNGPERHYEQSDYGNDRVGWGKTATDSWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAGIPKHDFYLYQSQWVSAKKKPMVHLLPHWNWENRELASKVEDADGKIPVRAYSNAASVELFLNGQSLGVKTFNKKQTSDGRTYQEGANAKELYLEWKVAYQPGTLEAVARDEAGKEIARDKITTAGQPAGVRLIKEEHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHGQGQLVGVDNGEQASRERYKAQPDGSWIRRAFNGKGVAIVKSTEQAGKFTLTAHSDLLKSGQVTVFTGKKEGQEKTVLGTEVPKVRTVIEKEPKMPKTVAFVYSDGSREKRPVTWSSVDVSRAGVVTVKGMADGREVEARVEVLAIAKELPTVKRVAPGTDLNAVDKYVSITVTDGSVQEYEVDKWEIAEADKAKLSVAGSRIQMTGQLGGETVHATLVVEEGNPAAPVVPNVSVGGEAVTGLTSQHPMQYRTLAYGASLPEVVASAENADVTVVQASAANGMRASIFVQPKDGGPLQTYAIQFLEEAPKIDHLSLQVEQANGLKEDQTVKLSVLAHYQDGTQAVLPADKVTFSTSGEGEVAVRKGMLELHKPGAVTLKAEYEGATGQIDFTIQANTETKVAQSIRPVNVVTDLHQEPSFPATVTVEYDKGFPKTHKVTWQAIPKEKLDRYQTFEVLGKVEGIDLEARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVTWDAIQSDQYAKEGVFTVTGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVSNVNDKLISFNDRPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVGAPKSYVIEYYVGKTVPTAPKNPSFVGNEEHVFNDPANWKPVTNLKAPAQLKAGEMNHFSFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPDLTDYYLESVDGKVPTVTASVSSNGLATVVPSVREGEPVRVVAKAENGDILGEYRLHFTGNKDLLSRKPVAAVKQARLLQLGQPLELPTKVPVYFTGKDGYETKDLTVEWEKVPAENLTKAGQFTVRGHVLGSDLVAEFTVRVTDKLGEALSNNTNYDENSNQAFASATNDIDPSSHDRVDYINDGDHNENRRWTNWSPTPSSNPEVSTGVIFRENGKIVERTVAQAKLHFFADSGTDAPSKLVLERYIGPDFEVPTYYSNYQAYDAAHPFNNPDNWEAVPYRADKDIEAGDEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTASKILVDGKELPDFAEDRQDYQITYKGQRPKVTVQERNQVASTVVDSGDNSLPVLVRLVSESGKQVKEYRIQLTKEKPVSEKTAPAIQEENPSLEVVEKELAFQTVEKEDPSLYVGESRVEQEGQVGKERILTSVSPDGTREEKLREVIQAPVNRVLLVGTKRGTAQPLDGAAGLVHEKPELLVEEEAIDFKVQERKTDKLYVGESRVLQEGQKGVRVHLVEVENGKRTLKETFDKIVAQDRIVEVGTKRGTAQPLDGVKDLIHHKPELLVEEEEVDFQVQERKNDKLPVGKTRVIQEGQKGVRVHLVEVENGKRTSKETFDKVASQDRIVEVGTAVAQEELNPQVPVNPDAHQLAQTGAQSQEEKVTQTEKGHLPNTGSESQVSALAAGLAILGLGAGLAATTRKKED
>NZ_CP034442.1|WP_000554838.1|967950_969666_-|aminodeoxychorismate-synthase-component-I
MHRKTVIDFRALGERYTFTQPIKELKTRDLAEVVDLLAQVESYQEQGYYVVGYVSYEAAPAFEEKLAVHKSPLLGEYLLYFTVHDRVEISPIPLTYEEVDLPSNWQEVTSAEDYEKAIAQIHHHLRQGDTYQVNYTVQLKQDLSANPFSIYNRMVVEQEAGYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDDEDLKEAAWLEQDPKNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLVVIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGILLPNGRRIFNVAIRTIQLHQGKAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLISTGKISQKQLLFEDQHLERLTKASRYFAYPFDPEDLRQRIEEECQACDSHQDYRLRITLNKSGELELSRQVLTPLSPGFCQAKLCLQETDLNQAFTYFKTTYRPHLSIGEQEKIYHNKSEELLETSIGNLVLKIAGKFYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLNQAETIYGCNAVRGLYELKVI
>NZ_CP034442.1|WP_000746261.1|969732_976230_-|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MKKRKEQFQKNLKYSIRKLTVGVGPVAIGAFLVGAGLLSAGKVQADELAEVNSVHYRYLTEQELTESEKALIHHEVPTEFQDEDIIYVVYRKKATTSQQLPYTGSKNLALVGLGLATASLAVLLVSKKHRSKVLGVLLISSIGVSNFVPFTAFAFENKELLSYNQTVSASTHEGLAKGVIHIEGYEYVGYFKDSKSTSNSNSSSKKGESLVQEPQEAYTGKIEAKGTQEPGKEGESLVQEPQAEFTGKVEAKGTQELGKEGESLVQEPQAAYTGKVEAKGTQEPGKEGESLVQESQSEFTGKVEAKGTQEPGKEGESLVQDSLPAYTEKLESKGSQEPGKEGESLVQDSLPAYTEKLESKGTQEVGQEGQSLVQGSLPAYTGKLESKGTQESGKEGESLVQDNSPAFTGKLESKGIQEPGKEGDSLVQDSLPAYTEKLESKGSQEPGQEGESLVQDSLPAYTGKLESKGTQESGKEGESLVQDSLPAYTEKLESKGTQETGKEGDSLVQDSLPAYTGKLESKGTQEVGKEGESLVQDNSPAYTGKLESKGTQEPGKEGQSLIQDSLPAYTEKLESKGTQEPGKEGESLVQDSLPAYTEKLESKGTQETGKEGHSLVQEDLPEYTVTEGTITKDTIAEIDYQTEIIDDPTKYTDEETVVQNGEKGIQVTKTTYKTVEGVETDQVLNTTTTVIKKPVTKKTSRGTKPIEGTLVEESLEKTPFKEIVEEDAQLKKGDKVTVQEGKDGQKKVIRTYKTIKGIKTQEAPEILEQVIELAQDSIVKLGTKNFEKPVLTFSRVDIQDLKRSSQIHYNLENPSKAAIKSITLTLKKGDEVVKTMMVSPDNLTATLTDLQYYKDYKLETKMVYDRGEGNEEEILKEEPLRIDLKKVEVKNIKETSLISVDDNGVETDSSFLTSVPSDVRPYYLKIATRDNKVTRLAIDKIEEVIVDGKTLYKVTAKAPDLVQHTDGNQLSEEEYVHYFAKPKTHEENVYYDFNELVKAMQANPSGEFKIGADLNAVNVPAAGKSYVTTKFRGKLSSVDGQRYTIHNLERPLLGDTEGAHIHDLNLGKVNIHMPWANRVAPLAAVIKNTTINNVKVTGTVVGNNDVSGLINKIDNNGRLTNVAFIGKLHAGGNQGAFLAGIVGENWKGSVEKAYVDAQITGNKAKVAGIAYWSQNGGDNNAVYRDGAIKKSVAKGTIDVREPISAGGVVGSTNALGSVEDTVSMMKVKNGEIFYGSSDIDDDPYWTGDRLNRNFVVTGVSEGKSSYRYSKQQHRIKPISQEEADKKIAALGITAHEYEINEPIVDKLNRLTQREDEYKATQDYRADRELAYRNIEKLQPFYNKEWIVNQANKLDASSNLVIKEVLSVTGLKNGQFVTDLSAIDQIMIHYADGTKEELAITAKADSDVKQVKEYEVTNQNIVYTPNMLVKDRAGLIAKAKETLSSVELISPEVRALMDKRNKPQENTDERKNGYIRDLFLEESFDEVKQNLGNLVKQIVENEDHQLNDDEAAQRAFIKKVEDNKANIMMGLAYLNQYYGIKYDGLSIKDIMMFKPDFYGKNVNVLDRLITIGSKENNLKGDQSQDAYSRVIAGATGKGSLHEFLTYNMKLFTNETDMNVWFKKAIEKNAYVVEQPSLNPDFAHKKYRLYEGINNGVHGRMILPLLNLKNSHLFMISTYNTISFSAFEKYGKNTEEDREAFKSEINKRAKEQVNYLDFWSKLAADNVRNKLLKSENSVPTPVWDNHDAPGIGWANRYGHKDGKPDYAPIREFFGRIHKYHGYQYGYGAYAYIFVAPNQQDAVYFVMTELISDFGTSAFTHETTHVNDRMAYYGGWYHREGTDLESFAQGMLQSPSLTNPNGEYGALGLNMAYERQNDGNQIYNYDPNKLKNREEIDHYMKNYNEALMMLDHLEADAVIGKHLDDNSKWFKKMDREWRTNAERNNLKGEPHQWDKLRDLTDNEKKLTITSIDQLVDHNFVTKHGMPGNGRYRSEGFDSAYQTVNMMSGIFGGNTSKSTVGSISFKHNAFRMWGYYGYLNGFIGYASNKYKAEASKENKGLLGDDFIIKKVSNGQFDTLEAWKKHWYKEVYDKTQNGFTTIEINGRSISTYAELKSLFDEAVQKDLDSMENPNIKNHYKNTEDLKWKVYKQLLQKSDGFSGNLFAKASL
>NZ_CP034442.1|WP_000360266.1|976232_976796_-|TIGR01440-family-protein
MDKNRIGTETQQVLEDVLDKAGLREGALFVLGLSSSEVLGGHIGKESSQEIGEIIVKTILDILEEKGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVLPTLHAGGSGQLAAFKFMKAPVEVEFITAYAGIDIGDTAIGMHVKHVQVPIRPVLREIGHAHVTALASRPKLIGGARAQYPQDSIRKI
>NZ_CP034442.1|WP_000274767.1|977039_977780_-|MerR-family-transcriptional-regulator
MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDLERLQVILYYKYLGFSLEKIAELLKAERTDLLPHLTRQLDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGREEEATAAFNRVFQALAQNLKNGLAATAVENQEEAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEFKQNIDKFGSGTAQYTSDVIAHYVQTQIK
>NZ_CP034442.1|WP_025168998.1|978031_979372_+|sodium-dependent-transporter
MSEKSQWGSKLGFILASAGSAIGLGAVWKFPYMTAANGGGGFLLVFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGNNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTAMLTYASYLDKKTNLVQSGISIVAMNISVSIMAGLAIFPAMSAFNIQSEGGPSLLFIVLPQLFDKMPFGTIFYILFLLLFLFATVTSSVVMLEINVGNITNQNNSKRAKWSAILGILTFVFGIPSALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALCLSLFTGYIFKKALAMEELHLDETPWKQGLFQVWLFLLRFIIPIIIIVVFIAQFM
>NZ_CP034442.1|WP_001294298.1|979411_980356_-|mannose-6-phosphate-isomerase,-class-I
MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKIGEYWAISAHPNGVSKVANGRFEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAYGLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDVLLTKVPVKAGDFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDNGNLRELHIEKSIDVLNIGEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSVLAGQGRLSVDGTNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP
>NZ_CP034442.1|WP_001291473.1|980613_980874_-|membrane-protein
MSEKQMKILGWVATFMSVMMYVSYFPQIMNNLAGQKGNFIQPLVAAINCSLWVYYGLFKKERDIPLAAANAPGIVFGLVTAITALI
>NZ_CP034442.1|WP_001052648.1|981079_981427_-|hypothetical-protein
MNLNQLDIIVSDVPQVCADLERILDKTSDYVDDGFAQFTIGSHCLMLLQSHLVPLENFQSGIILHIEVEDVDQNYRRLKELGVEILHGPAVTDWGTESLLVKGPASLVIDFYRMK
>NZ_CP034442.1|WP_000191810.1|981537_983313_-|pyruvate-oxidase
MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKDIRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAILGSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVVEIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGYGGVKAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLFLGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPVESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGDTTQTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPDVITNVQYDLPVINVVFSNGKYAFIKDKYEDTNKHLFGCDFPNADYAKIAEAQGAVGFTVDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKQHSEEAIKAFKEKYEAEELVPFRLFLEEEGLQSRAIK
>NZ_CP034442.1|WP_000136328.1|983526_985770_-|heavy-metal-translocating-P-type-ATPase
MTEIVKASLENGVQKIRIMADKGYHPAHIQLQKGIPAEITFHRATPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGQHEFSCGMKMQKGSYTVVEKTRKSLSLLQRFWITSIFTVPLVILMIGMSTGGISHQVMRWGTFLATTPIMLVAGGPYIQSAWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAAFIFFFVLMGAVFEEKMRKNTSQAVEKLLDLQAKTAEVLREDNYVQVPLEQVKVGDLIRVRPGEKIAVDGIVVEGVSSIDESMVTGESLPVDKTVGDTVIGSTINNSGTLVFRAEKVGSETVLAQIVDFVKKAQTSRAPIQDLTDKISGIFVPAVVILGIVTFWVWFVLLRDSVVVLGASFVSSLLYGVAVLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTIVFDKTGTLTEGKPVVTDIIGDEVEVLGLAASLEEASQHPLAEAIVKRATETGLELHTVENFQALHGKGVSGQINGKQVLLGNAKMLDGMDISSIYQEKLEELEKEAKTVVFLAVDNEIKGLLALQDIPKENAKLAISQLKKRGLKTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKLQSAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMSKKTFNRILLNLFWAFIYNVAGIPIAAGVFSGIGLVLNPELAGLAMAFSSVSVLTSSLMLNFSKID

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP034442_2	2.3\|967248\|42\|NZ_CP034442\|CRT	967248-967289	42	NZ_CP034442.1	967452-967493	2	0.952

1. spacer 2.3|967248|42|NZ_CP034442|CRT matches to position: 967452-967493, mismatch: 2, identity: 0.952

cggcttcggcgcaggttttggtgccggcttcggcgcgggttt	CRISPR spacer
cggcttcggcgcgggttttggtgccggcttcggcgcgagttt	Protospacer
************.************************.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	MF595878	Caldibacillus phage CBP1, complete genome	32401-32430	5	0.833
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NC_009958	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI04, complete sequence	9652-9681	6	0.8
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NC_014549	Glutamicibacter arilaitensis Re117 plasmid pRE117-1, complete sequence	46150-46179	7	0.767
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NZ_CP038031	Rhodococcus ruber strain R1 plasmid unnamed1, complete sequence	1139-1168	7	0.767
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NZ_CP034081	Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-3, complete sequence	7428-7457	7	0.767
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NZ_CP030933	Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence	722781-722810	8	0.733
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NC_008308	Sphingomonas sp. KA1 plasmid pCAR3 DNA, complete sequence	160549-160578	8	0.733
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NZ_LR594692	Variovorax sp. WDL1 plasmid 4	134001-134030	8	0.733
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	NZ_CP034352	Streptomyces sp. W1SF4 plasmid p2, complete sequence	269856-269885	8	0.733
NZ_CP034442_2	2.5\|967368\|30\|NZ_CP034442\|CRT	967368-967397	30	MT661596	Proteus phage 10, complete genome	47172-47201	9	0.7

1. spacer 2.5|967368|30|NZ_CP034442|CRT matches to MF595878 (Caldibacillus phage CBP1, complete genome) position: , mismatch: 5, identity: 0.833

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
aggcttcggcgcgggtttcggttctgcttt	Protospacer
 ********************* . * ***

2. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NC_009958 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI04, complete sequence) position: , mismatch: 6, identity: 0.8

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
ctttgtaggcgcgggtttcggtgtgggttt	Protospacer
*  . * *****************.*****

3. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NC_014549 (Glutamicibacter arilaitensis Re117 plasmid pRE117-1, complete sequence) position: , mismatch: 7, identity: 0.767

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
cggcatcggcgcgggtttgggtgtgtcgta	Protospacer
**** ************* *****.   *

4. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NZ_CP038031 (Rhodococcus ruber strain R1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
cggcctgggcgcgggtttcggtgtcgcggc	Protospacer
****.* ***************** *   .

5. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NZ_CP034081 (Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-3, complete sequence) position: , mismatch: 7, identity: 0.767

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
cgctttcggcgcgggttttggtttaggcgg	Protospacer
** .**************.*** ****.

6. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NZ_CP030933 (Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence) position: , mismatch: 8, identity: 0.733

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
cggcttcggcgcgggtttggctgtgacaag	Protospacer
****************** * ***..

7. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NC_008308 (Sphingomonas sp. KA1 plasmid pCAR3 DNA, complete sequence) position: , mismatch: 8, identity: 0.733

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
ggaattcggcgagggtttcggtgtagccgg	Protospacer
 *. ******* ************** .

8. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NZ_LR594692 (Variovorax sp. WDL1 plasmid 4) position: , mismatch: 8, identity: 0.733

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
tggcgtaggcgcgggtttcggtgtccgaga	Protospacer
.*** * *****************  *

9. spacer 2.5|967368|30|NZ_CP034442|CRT matches to NZ_CP034352 (Streptomyces sp. W1SF4 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
cggcttcgccgcgggtttcggcgggctcct	Protospacer
******** ************.* .  ..*

10. spacer 2.5|967368|30|NZ_CP034442|CRT matches to MT661596 (Proteus phage 10, complete genome) position: , mismatch: 9, identity: 0.7

cggcttcggcgcgggtttcggtgtaggttt	CRISPR spacer
atatcagggcgcgggtttaggtgtacgttt	Protospacer
  ...  *********** ****** ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

149642 : 159405

Streptococcus_phage(42.86%)

protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004246373.1\|149642_150590_+	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	8.0e-74	47.9
WP_141561220.1\|150688_150979_-	ferredoxin	NA	NA	NA	NA
WP_000410184.1\|150937_151432_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_000849393.1\|151441_152116_+	(d)CMP kinase	NA	NA	NA	NA
WP_000162311.1\|152234_152741_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	4.8e-25	42.5
WP_000442252.1\|152740_152911_+	hypothetical protein	NA	NA	NA	NA
WP_004240351.1\|152942_154175_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.2e-132	59.2
WP_000405203.1\|154183_154771_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_000598015.1\|154780_155161_+	RidA family protein	NA	NA	NA	NA
WP_000163027.1\|155212_156103_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	2.3e-06	30.6
WP_001231057.1\|156099_157077_+	YvcK family protein	A1IMD5	Streptococcus_phage	7.0e-174	92.9
WP_000011290.1\|157073_157985_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.1e-147	91.1
WP_000081028.1\|158436_159405_-	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	1.3e-63	95.2

DBSCAN-SWA_2

290183 : 299953

Klosneuvirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001291354.1\|290183_292181_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.6e-87	35.8
WP_000684203.1\|292197_292731_-	DNA topology modulation protein	A0A097BYE2	Leuconostoc_phage	1.7e-25	37.9
WP_001273999.1\|292783_293020_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_000180480.1\|293087_294008_-	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	8.7e-33	32.4
WP_004245862.1\|294212_294803_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_001202939.1\|294799_296077_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.1e-113	51.3
WP_000773694.1\|296096_296759_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_000246099.1\|296745_297135_+	cytidine deaminase	NA	NA	NA	NA
WP_001036146.1\|297225_298281_+	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	5.8e-57	40.3
WP_000929824.1\|298417_299953_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.1e-15	25.6

DBSCAN-SWA_3

762695 : 771109

Streptococcus_phage(77.78%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001166886.1\|762695_763568_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.0e-115	75.0
WP_000358229.1\|763570_763888_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.8e-28	60.0
WP_000806721.1\|763927_764818_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.9e-73	52.7
WP_000033373.1\|764814_765453_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-75	67.6
WP_000689667.1\|765570_766368_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	5.0e-61	52.5
WP_000255285.1\|766371_767634_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	7.0e-142	65.5
WP_080563338.1\|767643_768774_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.7e-116	59.5
WP_000403223.1\|768853_769753_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.0e-09	28.6
WP_000745694.1\|769736_770204_-	signal peptidase II	NA	NA	NA	NA
WP_001025717.1\|770200_771109_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.0e-06	27.0

DBSCAN-SWA_4

824118 : 834464

Streptococcus_phage(33.33%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000290631.1\|824118_824754_-\|holin	1-alkyl-2-acetylglycerophosphocholine esterase	A0A2K9L661	Tupanvirus	1.3e-06	25.3
WP_000593353.1\|824755_825580_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_001100688.1\|825858_826368_-	hypothetical protein	NA	NA	NA	NA
WP_000570835.1\|826647_826950_-	hypothetical protein	A0A2H4J224	uncultured_Caudovirales_phage	9.8e-10	33.3
WP_000415550.1\|827204_828524_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	4.0e-31	27.7
WP_001272965.1\|828689_829301_+	peptide deformylase	E3SLL2	Synechococcus_phage	5.4e-15	41.2
WP_000855721.1\|829344_830073_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272335.1\|830109_831021_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.3e-91	51.5
WP_000926603.1\|831086_831311_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590977.1\|831388_832132_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-27	39.2
WP_000219158.1\|832131_832932_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000889066.1\|833088_833445_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	7.5e-33	55.6
WP_000810632.1\|833457_833973_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	4.4e-42	49.4
WP_000405860.1\|833969_834464_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	2.7e-41	52.1

DBSCAN-SWA_5

893883 : 902762

Streptococcus_phage(25.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000613467.1\|893883_894474_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.7e-56	56.1
WP_025169005.1\|894652_895282_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_000136984.1\|895370_895838_-	deoxycytidylate deaminase	A7KUY9	Bacillus_phage	6.8e-34	58.4
WP_000003897.1\|895856_896414_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	1.5e-19	62.8
WP_000219960.1\|896538_897384_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	2.4e-106	70.9
WP_004246837.1\|897441_898623_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	2.5e-16	56.6
WP_000400041.1\|898636_899158_+	DUF1697 domain-containing protein	NA	NA	NA	NA
WP_001081773.1\|899167_899623_+	8-oxo-dGTP diphosphatase	A0A248SK16	Salicola_phage	6.5e-05	31.8
WP_000643814.1\|899682_900228_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000058058.1\|900480_901305_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.5e-73	56.8
WP_025169004.1\|901301_902762_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	6.7e-104	43.3

DBSCAN-SWA_6

1424081 : 1432838

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000513201.1\|1424081_1424921_-	energy-coupling factor transporter ATPase	A0A2K9L3Z8	Tupanvirus	7.4e-15	31.8
WP_000835741.1\|1424905_1425733_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	4.0e-21	32.7
WP_000712152.1\|1425729_1426275_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_125424912.1\|1426285_1427119_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000189299.1\|1427146_1428430_-	insulinase family protein	A0A2K9LA15	Tupanvirus	2.8e-13	27.9
WP_000424579.1\|1428426_1429677_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.9e-91	42.1
WP_000455878.1\|1429837_1430206_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	60.0
WP_000266682.1\|1430208_1431300_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000073410.1\|1431359_1432838_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	1.7e-94	40.5

DBSCAN-SWA_7

1484907 : 1496140

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000668250.1\|1484907_1487061_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	5.7e-43	27.9
WP_001182201.1\|1487073_1488423_+	HlyD family secretion protein	NA	NA	NA	NA
WP_000032091.1\|1488590_1489298_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SE76	Cyanophage	1.6e-42	40.5
WP_000361224.1\|1489354_1493080_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	9.6e-38	26.4
WP_000220661.1\|1493092_1494535_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.8e-54	34.7
WP_025168974.1\|1494575_1495598_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	5.8e-62	42.8
WP_000717477.1\|1495594_1496140_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.4e-24	35.4

DBSCAN-SWA_8

1539882 : 1550417

Streptococcus_phage(77.78%)

integrase

attL 1539777:1539836|attR 1552596:1552667

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1539777:1539836	attL	NA	NA	NA	NA
WP_000705443.1\|1539882_1541049_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	6.9e-160	70.4
WP_001233768.1\|1541145_1542660_-	ATPase AAA	NA	NA	NA	NA
WP_001080849.1\|1542989_1543610_-	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	9.7e-20	70.8
WP_000040966.1\|1543812_1544013_+	transcriptional regulator	NA	NA	NA	NA
WP_000424681.1\|1544027_1544657_+	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	3.6e-30	40.5
WP_004245827.1\|1544965_1545418_+	hypothetical protein	A7J274	Streptococcus_phage	2.5e-09	34.1
WP_000171249.1\|1545414_1545615_+	hypothetical protein	NA	NA	NA	NA
WP_001003753.1\|1545616_1545832_+	hypothetical protein	NA	NA	NA	NA
WP_001054702.1\|1545828_1546170_+	hypothetical protein	NA	NA	NA	NA
WP_000492117.1\|1546162_1546438_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.5e-30	70.5
WP_000214714.1\|1546578_1547439_+	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	5.5e-122	72.9
WP_000661062.1\|1547518_1548961_+	DNA primase	Q9AZI5	Lactococcus_phage	4.5e-60	35.8
WP_000173108.1\|1549269_1549803_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	2.1e-39	50.3
WP_025168970.1\|1549907_1550417_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.5e-47	52.7
1552596:1552667	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1609807 : 1647506

Streptococcus_phage(85.42%)

portal,holin,integrase,tRNA,capsid

attL 1592221:1592236|attR 1645913:1645928

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1592221:1592236	attL	NA	NA	NA	NA
WP_000745994.1\|1609807_1610992_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	1.0e-17	43.2
WP_000982054.1\|1611132_1612002_+	DUF2262 domain-containing protein	NA	NA	NA	NA
WP_000876915.1\|1612143_1613001_-	DUF975 family protein	NA	NA	NA	NA
WP_000592963.1\|1613107_1614253_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	4.1e-197	89.0
WP_025168966.1\|1614414_1615329_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	3.3e-149	87.8
WP_001257898.1\|1615342_1616143_-	helix-turn-helix domain-containing protein	A0A141E1D5	Streptococcus_phage	2.7e-131	88.7
WP_004246378.1\|1616312_1616549_+	DUF739 family protein	A0A141E1D4	Streptococcus_phage	9.6e-37	97.4
WP_001004038.1\|1616561_1617281_+	oxidoreductase	A0A1S5SCD7	Streptococcus_phage	3.0e-121	90.7
WP_000088838.1\|1617393_1617612_-	hypothetical protein	A0A1S5SF90	Streptococcus_phage	8.9e-29	80.6
WP_000398535.1\|1617969_1618260_+	hypothetical protein	A0A1S5S7M1	Streptococcus_phage	4.8e-46	97.9
WP_000462817.1\|1618271_1618586_+	hypothetical protein	A0A1S5SFB1	Streptococcus_phage	2.7e-42	92.3
WP_004246186.1\|1618598_1618898_+	hypothetical protein	A0A1S5S890	Streptococcus_phage	6.2e-41	84.8
WP_001185494.1\|1618888_1619761_+	DnaD domain protein	C5J987	Streptococcus_phage	6.3e-134	91.7
WP_000470299.1\|1619760_1619955_+	hypothetical protein	C5J988	Streptococcus_phage	8.2e-26	95.2
WP_000651969.1\|1619951_1620413_+	methyltransferase domain-containing protein	A0A1S5S9R6	Streptococcus_phage	2.4e-79	88.9
WP_000933622.1\|1620422_1620638_+	hypothetical protein	A0A1S5SCL8	Streptococcus_phage	1.5e-33	88.7
WP_000609564.1\|1620736_1621153_+	single-stranded DNA-binding protein	C5J996	Streptococcus_phage	1.4e-62	85.5
WP_001025454.1\|1621166_1621673_+	DUF1642 domain-containing protein	A0A1S5SE33	Streptococcus_phage	9.0e-40	50.9
WP_000429372.1\|1621673_1622009_+	hypothetical protein	C5J997	Streptococcus_phage	2.3e-36	90.5
WP_080563332.1\|1622180_1622615_+	DUF1372 family protein	A0A2H4JDE0	uncultured_Caudovirales_phage	4.0e-36	83.7
WP_000812325.1\|1622611_1623025_+	hypothetical protein	A0A2H4JBP1	uncultured_Caudovirales_phage	1.9e-35	58.5
WP_001247535.1\|1623021_1623393_+	hypothetical protein	A0A141E051	Streptococcus_phage	1.6e-57	90.1
WP_000801678.1\|1623414_1623651_+	DUF3310 domain-containing protein	E8ZDM1	Streptococcus_phage	1.6e-36	94.8
WP_001115775.1\|1623824_1624250_+	ArpU family transcriptional regulator	Q7Y4J3	Streptococcus_phage	1.5e-72	97.2
WP_000754879.1\|1624361_1624943_+\|integrase	site-specific integrase	Q7Y4J2	Streptococcus_phage	6.9e-68	67.4
WP_001095817.1\|1625157_1625502_+	HNH endonuclease	Q7Y4J1	Streptococcus_phage	9.0e-60	92.1
WP_004246082.1\|1625709_1626978_+\|portal	phage portal protein	Q7Y4J0	Streptococcus_phage	9.6e-224	94.4
WP_000426640.1\|1626967_1628047_+	hypothetical protein	M1PL14	Streptococcus_phage	4.1e-159	73.5
WP_000158851.1\|1628043_1628256_+	hypothetical protein	M1Q1E3	Streptococcus_phage	1.5e-25	77.1
WP_000101483.1\|1628360_1629773_+	hypothetical protein	Q7Y4I6	Streptococcus_phage	1.3e-266	96.9
WP_001288669.1\|1629853_1630321_+	DUF4355 domain-containing protein	Q7Y4I5	Streptococcus_phage	3.2e-60	87.8
WP_001287543.1\|1630332_1631235_+\|capsid	phage major capsid protein	Q7Y4I4	Streptococcus_phage	8.7e-171	98.0
WP_000852856.1\|1631237_1631459_+	hypothetical protein	Q7Y4I3	Streptococcus_phage	5.1e-32	95.9
WP_000426909.1\|1631479_1631875_+	hypothetical protein	Q7Y4I2	Streptococcus_phage	4.8e-65	98.5
WP_000532631.1\|1631861_1632200_+	hypothetical protein	Q7Y4I1	Streptococcus_phage	3.4e-59	97.3
WP_000064508.1\|1632192_1632429_+	hypothetical protein	Q7Y4I0	Streptococcus_phage	7.6e-34	94.8
WP_000569762.1\|1632429_1632765_+	hypothetical protein	Q7Y4H9	Streptococcus_phage	1.7e-55	95.5
WP_000513972.1\|1632779_1633331_+	hypothetical protein	Q9F4J6	Streptococcus_phage	6.7e-97	97.3
WP_000091190.1\|1633333_1633645_+	hypothetical protein	Q9F4J5	Streptococcus_phage	1.5e-45	92.2
WP_000616541.1\|1633659_1634040_+	DUF5361 domain-containing protein	Q9F4J4	Streptococcus_phage	5.7e-63	96.8
WP_000179873.1\|1634039_1636976_+	hypothetical protein	Q9F4J3	Streptococcus_phage	4.6e-221	80.5
WP_000386128.1\|1636975_1637671_+	hypothetical protein	Q9F4J2	Streptococcus_phage	8.7e-102	74.9
WP_000639863.1\|1637667_1641612_+	hypothetical protein	Q9F4J1	Streptococcus_phage	0.0e+00	51.8
WP_001005196.1\|1641608_1641818_+	hypothetical protein	Q9AF64	Streptococcus_phage	1.8e-23	84.1
WP_000996835.1\|1641807_1642395_+	hypothetical protein	A0A2H4J9Y8	uncultured_Caudovirales_phage	2.0e-35	46.0
WP_004246694.1\|1642406_1642706_+	hypothetical protein	X2KT07	Streptococcus_phage	5.5e-45	99.0
WP_001183890.1\|1642709_1643042_+\|holin	phage holin	A0A2H4JDE8	uncultured_Caudovirales_phage	1.2e-48	92.7
WP_000350544.1\|1643044_1643989_+	N-acetylmuramoyl-L-alanine amidase family protein	A0A1S5SCT0	Streptococcus_phage	3.9e-97	88.4
WP_001285237.1\|1644445_1645588_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.1e-85	43.0
WP_001220896.1\|1645688_1647506_+	acyltransferase	M1F3D2	Salmonella_phage	2.8e-19	26.3
1645913:1645928	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP034442

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection