CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP036526	Planctomycetes bacterium K23_9 chromosome, complete genome	4 crisprs	cas3,csa3,RT,DEDDh,WYL,DinG,cas1,cas2,csb2gr5,csb1gr7	0	3	0	0

1. NZ_CP036526

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP036526_1

• CRISPR_ID: NZ_CP036526_1
• CRISPR_location: 14950-15164
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP036526_1

Consensus_repeat	Method
AAGAAAAAAGCAGCTAAGAAGAAGCCTGCTAAGAA	CRISPRCasFinder

spacers of NZ_CP036526_1

>1.1|14985|25|NZ_CP036526|CRISPRCasFinder
ACGCGTAACTAAGAAGCGCGTAACT
>1.2|15045|25|NZ_CP036526|CRISPRCasFinder
GAAGCCTGCTAAGAAGAAAGCAGCT
>1.3|15105|25|NZ_CP036526|CRISPRCasFinder
AAAAGCAGCCAAGAAAAAAGCAGCT

CRISPR arrays and Neighbor proteins around NZ_CP036526_1

CRISPR arrays

The CRISPR arrays of NZ_CP036526_1

>merge|NZ_CP036526|1|14950-15164|CRISPRCasFinder
AGGAAAAACGTGGCTAAGAAGAAAGCAGCTAAGAAACGCGTAACTAAGAAGCGCGTAACTAAGAAGAAAGCAACGAAGAAAAAAGCAGCTAAGAAGAAGCCTGCTAAGAAGAAAGCAGCTAAGAAGAAAGCAGCTAAGAAGAAGCCTGCTAAGAAAAAAGCAGCCAAGAAAAAAGCAGCTAAGAAAAAGCCTGCTAAGAAAAAAGCTGCCAAGAA

>NZ_CP036526|1|1|14950-15164|CRISPRCasFinder
AGGAAAAACGTGGCTAAGAAGAAAGCAGCTAAGAA	ACGCGTAACTAAGAAGCGCGTAACT
AAGAAGAAAGCAACGAAGAAAAAAGCAGCTAAGAA	GAAGCCTGCTAAGAAGAAAGCAGCT
AAGAAGAAAGCAGCTAAGAAGAAGCCTGCTAAGAA	AAAAGCAGCCAAGAAAAAAGCAGCT
AAGAAAAAGCCTGCTAAGAAAAAAGCTGCCAAGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036526.1|WP_145415696.1|20857_21538_+|DUF3299-domain-containing-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145415692.1|16776_17184_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145415694.1|18736_19060_-|calmodulin-binding-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145415681.1|5910_6216_+|DUF721-domain-containing-protein	unknown	unknown	gnl|CDD|377496
NZ_CP036526.1|WP_145421970.1|24421_25423_+|TIM-barrel-protein	unknown	unknown	gnl|CDD|366542
NZ_CP036526.1|WP_145415685.1|7957_9160_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_CP036526.1|WP_145415684.1|7599_7929_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145415698.1|26057_27197_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP036526.1|WP_145415690.1|13558_14353_+|peptidase	unknown	unknown	gnl|CDD|100085
NZ_CP036526.1|WP_145415693.1|17180_18638_-|hypothetical-protein	unknown	unknown	gnl|CDD|226350
NZ_CP036526.1|WP_145415683.1|6944_7559_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145415689.1|12881_13460_+|redoxin-family-protein	unknown	unknown	gnl|CDD|376354
NZ_CP036526.1|WP_145415697.1|22553_23729_-|DUF4432-family-protein	unknown	unknown	gnl|CDD|379620
NZ_CP036526.1|WP_145415695.1|19379_20789_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421968.1|21766_22495_+|DUF3299-domain-containing-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145415682.1|6234_6867_+|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl|CDD|377025
NZ_CP036526.1|WP_145415686.1|9299_10427_-|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NZ_CP036526.1|WP_145415687.1|10494_11646_+|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NZ_CP036526.1|WP_145415688.1|11895_12828_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|223777
NZ_CP036526.1|WP_145415691.1|15426_16503_-|P-loop-NTPase	unknown	unknown	gnl|CDD|378455

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036526.1|WP_145421970.1|24421_25423_+|TIM-barrel-protein	gnl|CDD|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	1.45384e-05
NZ_CP036526.1|WP_145415681.1|5910_6216_+|DUF721-domain-containing-protein	gnl|CDD|377496	pfam05258, DUF721, Protein of unknown function (DUF721). This family contains several actinomycete proteins of unknown function.	3.14982e-12
NZ_CP036526.1|WP_145415685.1|7957_9160_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.77974e-09
NZ_CP036526.1|WP_145415698.1|26057_27197_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	6.54436e-73
NZ_CP036526.1|WP_145415690.1|13558_14353_+|peptidase	gnl|CDD|100085	cd06164, S2P-M50_SpoIVFB_CBS, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain. SpoIVFB is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown.	1.03551e-20
NZ_CP036526.1|WP_145415693.1|17180_18638_-|hypothetical-protein	gnl|CDD|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	7.92666e-24
NZ_CP036526.1|WP_145415689.1|12881_13460_+|redoxin-family-protein	gnl|CDD|376354	pfam00578, AhpC-TSA, AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).	1.19425e-12
NZ_CP036526.1|WP_145415697.1|22553_23729_-|DUF4432-family-protein	gnl|CDD|379620	pfam14486, DUF4432, Domain of unknown function (DUF4432).	8.24848e-121
NZ_CP036526.1|WP_145415682.1|6234_6867_+|DNA-3-methyladenine-glycosylase-I	gnl|CDD|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	6.42493e-113
NZ_CP036526.1|WP_145415686.1|9299_10427_-|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	2.06379e-166
NZ_CP036526.1|WP_145415687.1|10494_11646_+|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	2.717e-166
NZ_CP036526.1|WP_145415688.1|11895_12828_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.87323e-22
NZ_CP036526.1|WP_145415691.1|15426_16503_-|P-loop-NTPase	gnl|CDD|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.73985e-132

Protein sequences

>NZ_CP036526.1|WP_145415690.1|13558_14353_+|peptidase
MLLQEPPASQYDLRFNAFGFPVRIAWTFWLGALVIGFDFVRGMDMAFGEESPGMGPLLILWTAALFLSILIHELGHAFAFRHQGIHSSIVLYHFGGLATPVASMIPGRSIGRLTPKQDLWITFAGPLIQLAAAAVIMFGLKALGYEVAALKTLPAGLDVLSEYFPGERIENPALFAFTFFFVFPSIVWALLNLLPVWPLDGGHIMRSIVLLTGGDESQSLWISVGAAGLLAAYALTHGQTFMGIFFAMFAVQSFQMLQQRGGWR
>NZ_CP036526.1|WP_145415689.1|12881_13460_+|redoxin-family-protein
MLIRIAACLCLFIGSQSGRVGLAAETAQETGAIEIGEKAINFELPIVGKDDFIDLQNEYQQGIVVVVVLRGYPGYQCPLCTSQVSALINRARTLKDKVHKVVLVYPGESDELKRHAKKFLGARRIPEPIVLVADPGMKMVQSWGVRWNAPRETAYPATFIVKSNGRVAWKKVSQSHAGRSSVEEIVRQLKKL
>NZ_CP036526.1|WP_145415688.1|11895_12828_+|rhomboid-family-intramembrane-serine-protease
MGLYDRDYGREYGDETAWDRHQRSQDKKPKSAAIILMIITVVVHFVDMMSTQTVETQIGSQSLGWLYPYFATFHDTALKPWTWYQFLTYGFLHDQNEIGHVLFNMVGLFFFGRAVEQKLGFDEFIRFYLLSMLAGGIAGCAGFWLMGIDQGSVVGASGAVLATTILFACYNPNAEILLMFVFPVKAWIVATFFVISNVSGALGIFGSMGGSTSFTVHLAGIAFGLLYYYQQWNFAWLDFSKLSTMKQRMSQRSRRMKLKIHDPDRKIENEASEADRILAKIHESGEESLTSSERKTLERYSRRQRERRQS
>NZ_CP036526.1|WP_145415687.1|10494_11646_+|tRNA-2-thiouridine(34)-synthase-MnmA
MARIVLAMSGGVDSSVAAHLLLDAGHEVIGVFMRHGEESAQAYGEAACQATGGDPKSPPATSLPVVGALRQERADHKQGCCTASDAADARRVASAMNIPFYALDLQQDFKRIVDYFVDDYLSGRTPNPCVKCNHWIKFGKLFDYADGVDADFVATGHYARMQDGGLHRGRDSNKDQSYALFGIRPDRLPRMMLPVGDFNKPRIREIAEELGLGVAGKKDSQEICFVTQGHHSDFVKSRRPDRVGTTSGNIVTTAGKTVGTHNGYEAFTVGQRKGLGVAMGSPHFVVRIETETNDVVIGPQTSLQRNGLSADDANWLIDPNDLPENVSVQFRYNGSPKNATVKIDPADATQFDVVFDEPQLAISPGQAAVVYHDTLVVGGGWIK
>NZ_CP036526.1|WP_145415686.1|9299_10427_-|peptide-chain-release-factor-2
MESTTSWTPNWFNVAKRSTSACNSSETLFDHATKRAEIVTIEAKMAEAGFWDDNDAAQIVIGQLKGLKSIVGPLDELSSAVEDLGALFEMADEDESIAVEVSEEVTRLESILDNLELKALLNGPNDNAGAILQINARDGGTDANDWADMMLRMYSAWAVGQDYKIELLDRQDNEEAGINHASIAIRGPMAYGYLKGEEGIHRLVRISPFNSEGKRQTSFAAVSVSPEIDDSIDIQIEKKDVREDTYRASGAGGQHVNKTDSAIRLTHVPTNTVVQCQNQRSQHQNRDTAWKMLRAKMARLEEEKREAETALKYGTQARTGFGSQIRNYFLHPDQRVKDARTGHYVGNFNSVLDGSELQGFFDAFLRLRAGKQVKE
>NZ_CP036526.1|WP_145415685.1|7957_9160_-|hypothetical-protein
MSKPGLLYRIVVLIAVVQFCSIGSKSIACDWDSETLLQERMRFPTALEIILGKFPRHSDAFYEWRLKDRLEKLKENPDDDRLLDDVAVSYEKLGRYDEAIAVAKRQLAVTPDRYESLANLGTFLIHSGKLQSGVEYIEKAIEVNPDAHFGREKYQVHLINYVISSSVDGKVQLPLGSRDDETPAQKRENFYRYLPREMGAEKNKLSTSQANEAITGILGMMRFSRHDSPILLEVLGDLQLSLGANQLAYRAYKSAAINAKEKAAKDAYQQRAANSIHWQQYTWKVTENEDVPESALNDDFTRERKDAESWFASIVEQEAQWIKEGAAVDEKFNATYRGLQPTALETDPLRHVVTYDPRHSSGDDHNPVIGVVVIIGLCIVGVCVYVVSRLRRTKNLSDSA
>NZ_CP036526.1|WP_145415684.1|7599_7929_+|hypothetical-protein
MKQLLSIAIGIACCSVVEAGLQTRIDLPTPSSQGSNVESSEVYEYVPLAEQVFPETPDSQLLRKSKFQSQVNWLLKRQRQSSKWEERQRKLYERIRQQKLLENAEQKSK
>NZ_CP036526.1|WP_145415683.1|6944_7559_+|hypothetical-protein
MVGSQHTRATQVSRKSTFVVITMLSLFAVGSTGCATIVSEKRYPVTVTNTQAPTYFSIQNRKNETIHQGVTPQQVTLDAKAFPFWPAKYSVVFAGNDATTQTVPLKAKIDPWVAGNIVIGGVAGTVIDGATGAMFKLPAEVKGQIPPQFAVTDVNQGFSLAAAAVKVPAAAPVVATVSGQGVEPKVQTASARVGDYSQPATFRR
>NZ_CP036526.1|WP_145415682.1|6234_6867_+|DNA-3-methyladenine-glycosylase-I
MSVSKDTPSTTKLDDRIRRCWWCGTDPIYIAYHDDEWGVPVGDDQKLFEKMCLEGFQAGLSWITVLKKRDAFRKHFKQFDFTKVARLKSAAVDRMLQDPGIIRHRGKIESTINNANQAIKIVDEFGSLAKFFWQFEPSRSKVLRSRGQVQASTPESTAMSKELKRRGWSFVGPTTCYALMQAMGMVNDHLKTCDAWPRIDKARKSFKRPK
>NZ_CP036526.1|WP_145415681.1|5910_6216_+|DUF721-domain-containing-protein
MSDKPRVQRISTLVSQLMSRRGYAQMIAGEDFHATIGMAVGGQLGSAITVGKLKRGVLQIYAADSVSLQELNFQKRSILKQIQKDLPQSKVTDVRFRILTK
>NZ_CP036526.1|WP_145415691.1|15426_16503_-|P-loop-NTPase
MSLSVESVHQAIANYPDPETGRPLDKMNQIKSVDVDGSTAKLTIGLTTHSMPIVEDVRDALQSKIVAANPGTEVVIDFVVHDRPPARIGQIGLRAKSVIAVGSGKGGVGKSTVATSIALTLRRLGAKVGLMDADVYGPSVPHLLGLTGRPAIGENKKIEPIMLGDDMPVMSMGFLVEPDQAVIWRGPMLHGSINQFLSDTDWGELDYLIIDMPPGTGDVALTLSQALPLAGSVVVCTPQEVALLDAIKAISMFRKVNIPILGMVENMSGFLCPDCGKTYDIFGRGGARDKAEETNVPFLGGMPIDIKLRVAGDEGRLAEVLESDAAARAPLEAVTKSLVRSLATKAAANPPKASLPTL
>NZ_CP036526.1|WP_145415692.1|16776_17184_-|hypothetical-protein
MSGISPLIDPSLIQTWIVCESDQRWMTASRRFATHLVPAPMTVNLVSAEPNLVRRLLIGKRKAVVLWEIDGSCAARMYDLVASTSLGAPGILQIVAANGITPRDQMALTELGVGAIISQPEQLPGLSNLCLRYFK
>NZ_CP036526.1|WP_145415693.1|17180_18638_-|hypothetical-protein
MTGDGCLKHPPIFVYLHPVAMASGTKIRSLSRLLDASSAPLWVIGPKGTLIYLSAAVARWLGIDVDVLLDRHCVAGTSISDDPLDFVAASLSPPPGFNERGTASLRVQPPPIDGRKVTPLDVRFVRAGTASDSMTFAIGGQFDDAVADTGGATEVLQAVELRKKLDAWRAHHADIATIATAGVSSQARRMRTKLSVAASTRTHLAFFGPDGSGSLSIAMRVHQQSAPDEPLVRVEGPLMDPELLDATLMTTINQLSESKTTRVTVLVNELDDMPIEAQHRLSELLTTFAPRLRLIGLCTEQPRLLCEPLGESNDDDTISLEPESTIGLHPKLIDVLSTLSVVIDSLASRVEDIPVLATAALDTRRASGDGNAERFGRAALDALIVYPWPGNFEELESSVRHAIAAAPRESIGLEHLPLAIRSFRPGHADATQRPANISLDESVRRYEHKIISEVLEASDNNRAEAARRLGISRARLLRKIDEMNQ
>NZ_CP036526.1|WP_145415694.1|18736_19060_-|calmodulin-binding-protein
MLRHLIIAAVLIGSSAMLVEDASADQRAFGQSWGGQSASRDWNRFYHYPYVYYPQNFWGQEYYRSSDSMYHRYPQEMRVPVYNKKWHNYYPSNRRFHSGHHFNLDVF
>NZ_CP036526.1|WP_145415695.1|19379_20789_+|hypothetical-protein
MMFHRFSLAAPLILLAALATTSNAVACPFCNAVSQTLRQEMEVMDAVVIATAMQSDATRNKETGEILMKIDVVLKGDDLLKVGSEVKAVYYGEVKVGRRFMLSGVDPPDLQWSCLPINERSEKYIIAVTKLDDDPLERLRFFYDYLEDKDSMLARDTYDEFAIAPYSAIKELAPEMDHDQLVKWLQEPEMSTDRKRLYLTMLGVCGSKKDLPMLETLMTSTQKSTRGGLDALIACYLTLAGEQGLPLVNKLFLANKKAPYADTYAAIMAVRFHGTEGEVIARSALVESLHHVLDRADLADLVIPDLARWKDWSQIERLKNLFINADEDNNWVRVPVVNYLRACPLPAAAEAMKELEKLDPESVRRANTFFAIPVPAKDTGSSSSSVRRKATRKYAALPIVRDHQDPGSAKTGTLTASVSPVVPSFPPQLASDVSSSNPWTLLHVLAMALAALMIAQFLLLTGGAVVKQA
>NZ_CP036526.1|WP_145415696.1|20857_21538_+|DUF3299-domain-containing-protein
MSAELQMSAAADEADFPYRAISRAAIASVVFTVFALPGLVPTFEPMLFLAVIAIVAALVAMRAVKRYPDEYSGRAIALFSLIASLAILVGGVSMHTYIYLTEVPDGYERVPFFELQQPSDAKIDAPTELAYDIDGKPVFIKGYIHPSSGGGVLRQFILVPDLGTCCFGGQPKSTDMIEVTLLGGKTVKAGLTRRKLAGKFQLNSAPQVVTDFDNNVFYRLRVDQIK
>NZ_CP036526.1|WP_145421968.1|21766_22495_+|DUF3299-domain-containing-protein
MLVRPGSNASSPSSQPVPSATALSDAAQLEVAEPNVAQSDVAQSDVAQSDVAQSDVAQSSGDLESDLAPSDSQSANQTRQAVQTDQSTDAAIDPRTKGVVIKKSSAAARAKGEITFDDLQFKIKKDAKFTDEMLDDDVKSLDGINVRLTGFILPTTLFKETGIDQFVLVRDNQECCFGPGAALFDCVIVEMQGDNTTDFVTRPVTVHGKLKIDTKKYKYPGGKGPRGTTHFAIFRIEGQKVE
>NZ_CP036526.1|WP_145415697.1|22553_23729_-|DUF4432-family-protein
MVQSSNLRSIDNRLDSIQWKSKSPLTLDVETRQGDIKTRHGRFVGGAADQVEVIEVDTGVVRVYLLPTRGMSIWCVESEGVRFGWQSPVSGPVHPSQVPIFDPSGLGWLEGFDELVVRCGLESNGAPQHDEKGQLVYPLHGRIGNLAADSLSIEYDEASGRLEVIGEVRESRLFFKNLTLRSRLRVHAGSAKIELLDDVTNELSAPTTIQLLYHVNVGEPVLGEGSSIEIPLDELAPKDALSAGEIDQWNQYGPPEAGYAERVYFAKPRADEANECVALLRSANGERGVSVTFKIKGLPRFILWKNTGAVTDGYVTGIEPATNFPNERSYEEKQGRVVEIAGGETKSFRVSLTPLTDAESVNAASARIQAISGDEPADIHNVPRPGWSPGA
>NZ_CP036526.1|WP_145421970.1|24421_25423_+|TIM-barrel-protein
MWPGLVGKGDDEGQEPAISLEQMLDLTAAAEVDGQKFDGIDYFLFLPHTNPEASDDELRSIADMIQGKGFSVGSLVAPIWPGTIGDSAMGDKEQTDKFLSAVKMACRVAGIFNEHGVRKYGAIRIDSAEFGLEKWAEDPKGNTTKIANTFREAAKIAADHGERLACEGEICWAGMHSWKDMLDLLEEVAMPEALGFQADLAHTYLYLMGYNAPEHALLQDGYGQDEFYAKYEEMTDKLRPWTIDFHVAQNDGEVHGAGSHDKTGKHCRADDPNGKLDIVKCSGYWLKDAENRGIKHICWDGCMFPNSVLEDVGTWNTILDTMIQVRDAHCATV
>NZ_CP036526.1|WP_145415698.1|26057_27197_+|Gfo/Idh/MocA-family-oxidoreductase
MKPLNIGLIGYGFMGRTHTNGYKRANDFFPELEYRPVLKAVCGRNAQKVQEFADQWQYESIETDWKALIKRDDIDAIDICTPNNSHAEIAIAAAEAGKMILCEKPLALNPEEGERMCAAVEKAGVANTVWYNYRRVPAVTMAKQLIDEGVLGKIYHYRANFLQDWTISEDLPQGGAALWRLDAAAAGSGVTGDLLAHCIDTALWLNGSITDVSAMTETFIKERVHQDTGEKQAVTIDDACSFMCHFDNGSLGLFESTRYARGHKALYTLEINGADASIRWDLHDLHRLEFFSNADEGRLRGWRSIHVSDHSGDQPYMDKWWVPGLQIGYEHTFVHQVADFLKSLQEGKPCNPTFRDALETQEVCEAVLSSAKERAWKNV

Crispr_ID: NZ_CP036526_2

• CRISPR_ID: NZ_CP036526_2
• CRISPR_location: 4211209-4211289
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP036526_2

Consensus_repeat	Method
TCATCGAACAGGCTCCCGTCATCG	CRISPRCasFinder

spacers of NZ_CP036526_2

>2.1|4211233|33|NZ_CP036526|CRISPRCasFinder
AACAGGCTCCCGTCATCGAACAGGCTCCGGTGG

CRISPR arrays and Neighbor proteins around NZ_CP036526_2

CRISPR arrays

The CRISPR arrays of NZ_CP036526_2

>merge|NZ_CP036526|2|4211209-4211289|CRISPRCasFinder
TCATCGAACAGGCTCCCGTCATCGAACAGGCTCCCGTCATCGAACAGGCTCCGGTGGTCGTCGAACAGGCTCCCGTCATCG

>NZ_CP036526|2|2|4211209-4211289|CRISPRCasFinder
TCATCGAACAGGCTCCCGTCATCG	AACAGGCTCCCGTCATCGAACAGGCTCCGGTGG
TCGTCGAACAGGCTCCCGTCATCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036526.1|WP_145422380.1|4218323_4219964_-|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|235851
NZ_CP036526.1|WP_145419102.1|4221434_4222283_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145419084.1|4205745_4206999_+|DUF1573-domain-containing-protein	unknown	unknown	gnl|CDD|377880
NZ_CP036526.1|WP_145419076.1|4197396_4199970_-|hypothetical-protein	unknown	unknown	gnl|CDD|226685
NZ_CP036526.1|WP_145419098.1|4217069_4218044_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145419094.1|4216035_4216818_+|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl|CDD|379084
NZ_CP036526.1|WP_145419080.1|4201209_4201785_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl|CDD|376771
NZ_CP036526.1|WP_145419096.1|4216836_4217073_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145419100.1|4220226_4220733_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145419104.1|4222481_4223039_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145419082.1|4203156_4205646_+|O-antigen-ligase-family-protein	unknown	unknown	gnl|CDD|377422
NZ_CP036526.1|WP_145419074.1|4197090_4197324_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145419086.1|4209939_4210806_-|PhzF-family-phenazine-biosynthesis-isomerase	unknown	unknown	gnl|CDD|223461
NZ_CP036526.1|WP_145422378.1|4207814_4209398_+|hypothetical-protein	unknown	unknown	gnl|CDD|372604
NZ_CP036526.1|WP_145419105.1|4223109_4232712_-|CHRD-domain-containing-protein	unknown	unknown	gnl|CDD|377837
NZ_CP036526.1|WP_145422377.1|4202092_4203178_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl|CDD|133463
NZ_CP036526.1|WP_145422379.1|4209460_4209922_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NZ_CP036526.1|WP_145419090.1|4211993_4214396_+|DUF1592-domain-containing-protein	unknown	unknown	gnl|CDD|377886
NZ_CP036526.1|WP_145419092.1|4214452_4215712_+|DUF1552-domain-containing-protein	unknown	unknown	gnl|CDD|377875
NZ_CP036526.1|WP_145419078.1|4200094_4201213_-|phosphotransferase	unknown	unknown	gnl|CDD|366736

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036526.1|WP_145422380.1|4218323_4219964_-|S1-RNA-binding-domain-containing-protein	gnl|CDD|235851	PRK06676, rpsA, 30S ribosomal protein S1; Reviewed.	1.1046e-103
NZ_CP036526.1|WP_145419084.1|4205745_4206999_+|DUF1573-domain-containing-protein	gnl|CDD|377880	pfam07610, DUF1573, Protein of unknown function (DUF1573). These hypothetical proteins, from bacteria such as Rhodopirellula baltica, Bacteroides thetaiotaomicron, and Porphyromonas gingivalis, share a region of conserved sequence towards their N-termini.	2.03568e-13
NZ_CP036526.1|WP_145419076.1|4197396_4199970_-|hypothetical-protein	gnl|CDD|226685	COG4232, COG4232, Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion].	1.93024e-57
NZ_CP036526.1|WP_145419094.1|4216035_4216818_+|zinc-ribbon-domain-containing-protein	gnl|CDD|379084	pfam13240, zinc_ribbon_2, zinc-ribbon domain. This family consists of a single zinc ribbon domain, ie half of a pair as in family DZR. pfam12773.	0.000216907
NZ_CP036526.1|WP_145419080.1|4201209_4201785_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl|CDD|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	7.93206e-41
NZ_CP036526.1|WP_145419105.1|4223109_4232712_-|CHRD-domain-containing-protein	gnl|CDD|377837	pfam07452, CHRD, CHRD domain. CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..	6.39095e-17
NZ_CP036526.1|WP_145419082.1|4203156_4205646_+|O-antigen-ligase-family-protein	gnl|CDD|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	2.2443e-11
NZ_CP036526.1|WP_145419086.1|4209939_4210806_-|PhzF-family-phenazine-biosynthesis-isomerase	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	2.01399e-80
NZ_CP036526.1|WP_145422378.1|4207814_4209398_+|hypothetical-protein	gnl|CDD|372604	pfam13435, Cytochrome_C554, Cytochrome c554 and c-prime. This family is a tetra-haem cytochrome involved in the oxidation of ammonia. It is found in both phototrophic and denitrifying bacteria.	9.51278e-19
NZ_CP036526.1|WP_145422377.1|4202092_4203178_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl|CDD|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	4.48722e-61
NZ_CP036526.1|WP_145422379.1|4209460_4209922_-|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.58648e-25
NZ_CP036526.1|WP_145419090.1|4211993_4214396_+|DUF1592-domain-containing-protein	gnl|CDD|377886	pfam07631, PSD4, Protein of unknown function (DUF1592). A region of similarity shared by several Rhodopirellula baltica cytochrome-like proteins that are predicted to be secreted. These proteins also match pfam07627, pfam07626, and pfam07624.	4.93186e-60
NZ_CP036526.1|WP_145419092.1|4214452_4215712_+|DUF1552-domain-containing-protein	gnl|CDD|377875	pfam07586, HXXSHH, Protein of unknown function (DUF1552). A family of proteins identified in Rhodopirellula baltica.	9.096e-74
NZ_CP036526.1|WP_145419078.1|4200094_4201213_-|phosphotransferase	gnl|CDD|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	6.62861e-05

Protein sequences

>NZ_CP036526.1|WP_145419086.1|4209939_4210806_-|PhzF-family-phenazine-biosynthesis-isomerase
MTDSLPIWQVDAFANAPFTGNPAAVCLLPQYPSDQWMQNVAAEMNLAETAFVVPTDDAEVFHLRWFTPAIEVDLCGHATIAAAHVLFQQNKVGTDAVIRFQTRSGELACRAVSNPTASLDQSSSNSGEVWIAVDFPVTASINRVEDSVCAQLQAALGVPAIEVRKTIYDIMVVLRDAASIRSLTPNLHLLAQIDTRGVMVTAPGDIEGVDFVSRFFAPQSGIDEDPVTGSAHCCLAPYWGQRLGKSVLAGYQASPRGGTVYCEVVGDRVKLSGHAVTVMSGQLLVAPE
>NZ_CP036526.1|WP_145422379.1|4209460_4209922_-|GNAT-family-N-acetyltransferase
MLRSWTVSDSADCLTLFRDCIRRVCADDYTPEQINAWASPQIVFDDWAQRFQNRSAYVACQRDAIVGFIDMDDFGYLDRLFVSADHQRQGIARRLVDQVVADAKRLGCQRIKTEASLTARPFFQSMGFAVVKQQVVECSQVQMINFQMQLSLS
>NZ_CP036526.1|WP_145422378.1|4207814_4209398_+|hypothetical-protein
MKPELVPTPEGVPDTAKTPPAMNPDAPQLAPLQPATPAKTDPTKDKDAPMPGGLKSVTDEGTSAIPVELRPEAYSTWETPDVTLFVTGQQNGYIEPCGCTGLEKQKGGVARRLTFMNQLRDQGWDLLPIDAGNQVRRVGRQASIKISWSTEALKKMQYESVGFGPDDMRLPATDLLQLAFADSPEEAMYISANVVLYDESYVPIMKVVQRGKHRVGITNVLDPDALETGVTTEALIKPAIESAKAALAAMEKDNATFKVLSFYGKEKDAVELVKAVPGFDLLIAAGGYGEPTYRPQAIEKSKTQMIVVGNKAMYAGLIGLYSNGPFKYARVPLTHEFADAQEMRKIMGQYQDHLKQVGFRELGLDPIPHLSGEKFVGTATCAQCHEDAFDVWSGSMHATATDSIAAPPEDRGDVPRHFDPECISCHVTGWNPQGYSPYASGYESLEASKHLLGNGCENCHGPGESHSKAERDDSGVSDDEKARLRKSMQLPLSRAKEHCMKCHDLDNSPDFHEPDAFEDIYWPEIEH
>NZ_CP036526.1|WP_145419084.1|4205745_4206999_+|DUF1573-domain-containing-protein
MKHFWLLLTLCGGVGLSAAWALNQAKYGHRDAYLDRLNLKDVTADNVIELVKADQKSSGARVELLSEESHHFGSMAPGDEGEHTFRIKNVGTEPLSLKEGASTCKCTIGTLNQNTLAPGEETEIVVSWTVKTQKKDFSQKAQVITNDPHKVVLDFVIQGDVVRDIEFAPRAIQFGEVAAGEPFEVEAQMYSFYDNEIEISEVKFLSEQMNKLSKFDVEPFDPTVGEGEFSKATRGYNIKARVRSGLSQGAVATRMQVVFHVRDNQGEFVKEDESRVPVSFLSDVETTGFIAGQLSMVESTKIKSRQGAYVIELGALEDDDSKKARGFIKLKGSERDNTNLSIGEVEPAEAIQAKLGKPIKQESTVLYPLELEIIPGDKPFDLRGKSKGDYGTIWIETDNPKVPRMLIGVKFSIDAKQ
>NZ_CP036526.1|WP_145419082.1|4203156_4205646_+|O-antigen-ligase-family-protein
MAKKRRVKPAHNHSPERASVSAASSDSNASSSQSVADESLPPARLEPIAIASALLAGALVYVTYHPSDSVAVERGDALWFGVIAIVIATLTLARMAWLGRLPQQLKSPAVVADALACGLAIWMMLAAFATCPPGNLRMATNEAWLWVSGAAIFCASRRLMSSLAVRQSMTALLIVCSIGVAVHGLHQNWISLPASRAEYRADPDKLLAKAQIQAPPGSVERMVFENRLFDGGPTGTFALANSLAGMLVMGCVLIVGVLRLQWSTMTNYQRVGWITGLVIALVCLWAARSRSATAACVLGMIAVSIGPSLFALSDRSSRDQDSDNDAASTVGHARKSKRFRAVIMGGAALIASAIGILSLIAAVGNKEWFEQAPASIAFRLQYWRSTWQMTLDHPAFGAGPGNFQSIYQRYREESASEEVADAHNFLFETLAAGGFVSLALLLCLLAWTAWTISRRLINPTRELPADSTEEASGDDLAKWVWLGSGLSLLMIWLLGAASGHTPDFQAHRFAVPIACVAAVLLWPAVSRCSSAALDLFSIVACGSLMVHLLAAGGWTVPGVAMPIWILAGAMTRIPATRTVATTLQNDARTDNQSRKHRWPATLGVIAIGAVLLLAHRTVSLGPVEKNHLAMRIADVARSQQQTAALGKAVDQAIAADPWSPEASLYKADLLRWDLIVRGDQPSMRSMWHTQLQDMLLRAGENPTLYRAAGQQSLHLYQRFGDDEYLQIAADYLTQATQWSPSDHALSAQLAAVADRQGDVQLARTLAAKAARLANLGENVERQLSRQMIYLAEPVGRRANSSPVIGPASEVLAKLLTPNQIDAAPVVNQN
>NZ_CP036526.1|WP_145422377.1|4202092_4203178_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MLICALSLYPVRRFAVKLGLMDLPGGHSSHTQVTPLGGGIGIWLGIVGTFAAGTFAVALARGSDSIQAKLPPGVVPYLEGVWIRAGEFWCLLACATVLFVLGICDDRRGVNVAIRLGVEFAVSAFVVYGLGFGLTAFIGVPWLTNLLSVVWIVAVINSFNMLDNMDALSGGIAAIIAGSMAAVMLSTPDPGTARPQLFVAALLLVVCGSLLGFLWHNRPPAKIFMGDGGSYLVGFLVAVAMLMATFAGGGDQPRPHAVLAPLCAMAVPMYDMATVLWIRIREGRSLVKGDHSHFSHRLVGLGLSRGRAVATIYLVTGTCGLAAVLLTHVSLLQAIAVLGIVACMLLLVVILESTQWRKNDA
>NZ_CP036526.1|WP_145419080.1|4201209_4201785_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MTSPRFGFLSLRQPSLAPCKTNLVTTPDSASGILISALDLPAIGRFADQLVSQFPDTLVIGLVGTLGAGKTTLVQSIAAAAKIDVAEVTSPTFTLLQTHRGTLTLHHLDAYRLADEDEFLELGVDELFEQPGAWTLVEWADRIADVMPTETLWITIELTSDDARRDLRLTCDDDATREKITAVARQLGADA
>NZ_CP036526.1|WP_145419078.1|4200094_4201213_-|phosphotransferase
MIDNTLPPAIARSLVSLHGVTEVVAVAPGMSGARVFRCQSYDGRQFALRRWQSQASPKRIAEIHRIVASAYGNGCTMVPQQLPMDFHGNTCPSFDGSTWDLATWVTGSPLPADATVQQIAAGAAAIGRFHQAVATMGNRMQPAPAVRSRLSRAAEVDRLLPRLQGVDWSACPEILIRPLARARDQLQTKWASVHHEFARSIRGYHDADVLTQYVIRDVHRGHILFTSTDSDQVAESVAMETTATKTDATDDAATSYRATGMIDFDAVRVDTPVTDLVRWGGSFLDSHHLGDCGADAIWDSVLAGHQRESTSLQSWRAGEFRLLAGQLHRISTWISLANWLDWLTIEQRKFPTNDQMVARRIDELADLADLEL
>NZ_CP036526.1|WP_145419076.1|4197396_4199970_-|hypothetical-protein
MQDILMPANNETRQPSVGSSSRVFGRTKSTSAKSARRTIRPSVFAIKFVVALLVTLVGLPLAAPQLSLAPAMAQGGFKLPMSVRSLGIQNEDPATWSATYRVVPGTDEGVLEVEVVLSQGWHVFSTTQESGGPIPTSITIAAPKAVQLSGAFQPDHEPESAESDVFEGVTIEEFHDSVIWSAKIVLPPGYQGDIEVAVDGQTCSEAGSCTPVQESLVAKYTGEAKPVQTVADTATAKVTKLDLAKAKPYREPKNPVQWKAAASKSIAAGDRGVLQFNATLDPEYHVYTAAVDDANSSTNFIVTNKSGLKVGMPTTPTKIIVDNTLPTLPMKYHDGDVTWSLPVQVPAGTAAGEHKIEGFIVYQACTKSACYPPTALKFETVIVVGDGAAGSTVVSMKPAKRPVALDAADGNKWVDELDAAGNAPAAGNQSQSDASTSQAPPINPSTPDQVSAAESPPSPDSSGSNSKADSRIADSASAASAISSVVVKDSPEEIAEMAKLYNVDEKIRYLTLSDMDSNPIGSGGVSSSDTMTFWSALFGAFVGGIILNLMPCVFPVLGLKVMGFVKQAGNDPAKIRMHGIAFAGGLLVAMWVLAGIILTIKISLGTNINWGAQMSEPYFVCAMIVLLFLLGLNLAGVFEFGTSMTRVGGSIQGKEGYSSSFLSGVLTTLVATPCSGPFLGAAMSYTLAQPAGIAMILFTVFGLGIAVPYLLLCFFPALINRLPRPGAWMETFKVTMAFALFATVAFFMQAFGSQTGASGLSWLAMALVVIALAAYYYGNYSAPHVPDGKRWAFGYIMPLAIFSLGAWMCYGAANERSTAESSYHAGGLAWQDWNPGKVEQTLRRKKKTVWVDYTADW
>NZ_CP036526.1|WP_145419074.1|4197090_4197324_-|hypothetical-protein
MELIVVDDTLREERISRDLARADRQILPVNLIYPPNYPEEPAILLDEFIGPADALKVLERMEKIQNNLASSRLAVNH
>NZ_CP036526.1|WP_145419090.1|4211993_4214396_+|DUF1592-domain-containing-protein
MISLRHFIFVFAVIASGPLRAATLRDELAPLIDSSCVDCHDASTETNLDLTSLGTDLTDDSTQRQWEQIFDRVWTGEMPPASEDRPPTEIRSAALTTLKHSLAEASLAKQKSGRVPARRLTKLELRYTLQDLFLIQGDVTNGIPDESESGSFDTVGASQRISAVHLESYLAAADEALDLAIRLDHNPYRDFGDKADDDFGFLETWHDKPLNLGGSITRKLNYGSGVVLFADVDYLTQFVASVPSPGRYRLTAKVAAYQSTEPVTAKWIVKNQSGGAKLAKTVDLLPGEPTTILVETTMKPGDIPYLTFDNRNAKNDSVFIAGGSQVFQGAGLAILSQSAEGPLNQSWPPPSTMHLLDGLEISEILGCQDGPFEVIATANPIDDIRRIVSRLAPSIFRRPVSETELEQFVSLASPALDAGRDITDALRIPLRSMLSSPQFLLLGGRSGQLDDHALASRLSYFLWRSMPDPALLQLADQGQLRDPTVLAQQVDRMLADPKADRFVKDFVGQWLRLHQINATSPDESLYPEFEELLAAAIPKETQWFFADLIRRNLSADNLIDSDFTFVNRRLAQHYGIDGVDGQHFRRVALPDDSPRGGILTQAAVLKTTANGTTTSPVTRGNFVLTNFLGTPPAAPPASVGSIEPDTRGKTTIREILSAHRDNESCNQCHREIDPPGFALESFDPIGGFRTHYRASGGEQTFGDFTTKLPPKQGPPVDPSGVTTDGTPFRDIRQYRQHLMQNRRAVVRNFISQLIVFSTGGEIAFADRDVVKEITDATEADGFRVRDIIHAIVQSRLFDEK
>NZ_CP036526.1|WP_145419092.1|4214452_4215712_+|DUF1552-domain-containing-protein
MTSRLPRRTLLKAAGVSLSLPFLESMTAVQAASQVAPPKRMVFVCTSLGLHSPNLWPTTTGKEYESTPYLDLLNQHRNDFTLFSGLSHEDQIGRQPHDSEMTWLTAARKPGVAGFRNSVSVDQVAAKHFGNATRFASVTMGTIKSQSQSYTDGGVMIPAQTSPARLFAKMFLNGTPDEIIAQKRRLLDGRSILDELGSQTKRLKQQASAADNHLLDDYFHSVRQAETNIAAADGWSKQPKPTVDTQQPKDINDPTDLIGRSRLLLDLVPLIIQTDSSRIISVMIQDHFVVPKIDGVRGTHHNLSHHGQDPSKIAELQRIETGIVQCFGGMLEKMKSGQESGTRLLDNTSVVFGSNLGNANAHEAKNLPIFVAGGGYQHGRYVDMKKEHETPLSNLFVRLLQDTGIETESFGQSSAAMSW
>NZ_CP036526.1|WP_145419094.1|4216035_4216818_+|zinc-ribbon-domain-containing-protein
MPIQVKCQCGKALKVKDELAGKAVKCPGCGKVIKIGQKAAAPVKPSVKPSAKPASKPAAARPPAAAAAPVGGGDSLDDLFDEEGFSDHVASLCPNCRAEMSTGAVFCTKCGFNKETGDLMQAHKTAGVDIDAGTMALDKAEADMKKADRLQREMESKAGMPWWMLALVIFMMGSGTAIAVIAVNMANRTEEGSASEFSAMALFLQVCAGAVSFLSVGALLKLGILFAKKEAQKKDIIKLTIGFLLFGGIGIGLLVAASRQ
>NZ_CP036526.1|WP_145419096.1|4216836_4217073_+|hypothetical-protein
MPWPASIALICITVSMFATLLLELWTGLAVAGWAGDFALVDRQKQPIIYWAIMLLQISSLVVTIAVAYYFVVAPAAAL
>NZ_CP036526.1|WP_145419098.1|4217069_4218044_-|hypothetical-protein
MNASPRLFDDVSQDVPMSHQAMDVVEVDLAENAPLLFRFDGNTSSDPDRASVGLGLAGLGVLLFCLSVAIPLGIELVEDVFSGRPAFWVMGGVAMLVIFPAGSVGSFSIAAAMFWHVPLVIRYAVAIALFVPSVVGFTISLAMVETVDWADIVPSVAVLFSSVFVCAATVGILAQLCTPWTLAHLRTTSEQLPRLGIQTLIQLTTIVAITFAFVSVLKSEVPIEATLAFGGVSALGAVMGIVACVAYLRDAPVGRKGVIASCVTAFAMSFAFVACLATVEFGWQSVVYQAHVTLPLSLFGAAIIGAFTSACVYWLRQCGWRCVR
>NZ_CP036526.1|WP_145422380.1|4218323_4219964_-|S1-RNA-binding-domain-containing-protein
MTTGDQTPESSDVTETTAASNAAAVETSPAQSPAEPTAASATAPTVTEPAAAAGKPAARPTGPLAARGLGVAKPASPSVSPELLKAAGEAQNATIDKPKAKPGAGKKKQHKVKTSGVTGQNTAPKTPRVKVAVPSLRQELPDDIQAELDAELAAADFDAIMSGPAGMPERKEPLEEGQTVHGQVIKIQTDTVFLSLGGPDQGTLAFEQFTGEEPVPGQSIEVVVRGLNSEDGLYALSLPGSTVAVADLGDIDEGAVVTATVTGHNKGGLECKVGGVSGFMPISQITEYRVEDLSEFVDQKMVCLVTEANAGRGNLVLSRRAILEREREVKRKEQLEKMEPGDQMDGVVRTIKDFGAFVDLGGCDGLIHISKLSWDRIKHPSELLEMGQQVSVVVDSVDKETGKISLSYRDLQENPWDTAEAEFAVGTNHKGSVTRIAAFGCFVRLAAGVEGLVHISEMAHHRVSRIDSIVSEGEEVEVKVLSFDRDAQKIGLSIKAAQHVPESEGKKDVEEVDEPPREPVVKATHSGPLKGGNNASAGGEKFGLRW
>NZ_CP036526.1|WP_145419100.1|4220226_4220733_+|hypothetical-protein
MPEIAGFASILTNALSPQLASAVTQSAMPGLADGPRNDALATILSSGDLQTHLAGAGDRVDEIISGLWLLAGDLDRSHTISQDLPSAEGSFLHGIMHRREGDFGNAKYWFRRVGDHPVFDQIAQAAGSVYDDPSDFVDLCSDAIRRGEPDDCMAAQWIEWQCIMAYLC
>NZ_CP036526.1|WP_145419102.1|4221434_4222283_+|hypothetical-protein
MHCITLAEVAAILSQHGPDLISSQTEIRSEAVTCYWASSRRRIAIWHGLLAEHRAAQRVGDTVDLRFWWDRNMPLLEEIIVSEMLTRVVAAVTAEIESANASAKGRDEVSPVTHTIFLAHLDVSHRVHRLMIHREGYSVHHAVRLNRLRQGVQRWNDALIGRLSMQPSEALAFAFDHDRAATFAKESRERGVHAVRNVSCWLMNASMRDMLSRRVSTEAAFPEANQDVADSVMSMLQPELFDDLGTLKSGWLHRIGQEQSSPESMPEFKKPNLDWSMGNKEL
>NZ_CP036526.1|WP_145419104.1|4222481_4223039_+|hypothetical-protein
MLRYVPTALSCLMVLSCAWADEPCSGVDAPKSKPNAKPSARITATTCKFTFPVDDLDQTWEWGVSPLNACEYSWMVTVKLKEATFQIGVSHFNAFGIAQSGSFDDFLRASQADVWKLKPDKQGATVVDGIKVICKSNGPALEITVDDADWSAAVFAQRPALVKLQTTGTRLKKSEHAVKIKYKSD
>NZ_CP036526.1|WP_145419105.1|4223109_4232712_-|CHRD-domain-containing-protein
MMVRIASCNTLSSKHNCVLIDHNLIHPTISTGNSMLSTENASAETPASLRTSSRHKRRRSRPISSRRAARTRRLSCETLEARRVLTAYLVTTLDDTVAADGEVSLREAIQASNTNAAVGDAAAGVSGAVAGAPGDSITFAAALSSETISLSGGQFSISDDLAIALGDASSITIDGGGDSRVFLIDGGGPSSIDGLTITGGNDVNGGGMFVSAGQTLTLSNVNISGNVATGDAATEGGGGVYSEADSLTISDSVIESNQASGASGSGGGIFSAAGSTTLDATNVRFNSANRAGGGVEVGVGTFVFQNNSALTNNDVNGLSVLATAPAPGNGGGLHVTGAANVSLTGGSVFGNEAASEGGGLWNNAGTMTIDGTLIDSNFVESIGGDADAQGGGGVFNNGGILNISNATISNNEALDPDAGATQDDGGGGLFNNGGTVTLTDTDLTANFATDGLGNGGAILSLGGSVVISGGTITANEAARAGGGIENNDGAVTLNAVTVGGIAGADGNLAGINGGGLHVSAAGTTNVNDGSFQNNVAMREGGGLWNNAGTMTIDGTMVTGNTASGDESHDGGGGVFNNGGTLDIIGATISANLANGASGSGGGVFSTDGDVDIQSSTIGLNGANRAGGGIEIVEGNLTLTGSNLVNNDVDGTATGGPAAPGNGGGLHVSGAVTTVIDGGSVFGNVAQAEGGGLWNSGTGTMTIRNGTIIEANEALGDSADQGGGGIFNNGGTLAINGTASAIAVVDNFASGTSGSGGGLLSVGGNVTIDNADFDLNAANRAGGGIEIAGGTMTINDTNLTNNDVNGSAGMAAPGNGGALHISGFAVVGLSGGTVSGNAAANEGGGLWNSNVGILGVDGATIENNTAVVGGGIFTQSGSAQAVRLTMVNSAPNGGPTDSGLFLTPVFTAFHDGGFDLFNAGETASAELERIAEDGNNGPITAAFAAGQANGVSASLPGGPFSPGATETAVFVLDPVDNRYYSYASMVIPSNDAFIANDDAQMLELFDADGNLLPIDFTVTGAAVWDAGTELNDETDAAFFDQMAADTGTAESAAVTSHAGFINSVGNPGGTSIILGGTQSVGPMRTFGTANADFTSDGYELLQVTIEDAGSGTSLVNVIVNANTATGDAATEGGGGIFHGDGLLRITGGAITNNVANGMAGSGGGILNLGGTIEVTSAAITGNTANRAGGGIESAANSMTNLMDVNLDDNIAGPASLAAPGNGGGLHITGAGDATIVGGTVSGNFAAAEGGGLWNGTGTMTIDGTTIQDNSAAGNASDQGGGGIFNAGGAVDIARATISNNLAASATTFALSGTQEVPSVTTTSMGQASLQYNPLSGTFRLDAFVSGIELTDQTALPELTGAHIHLGDAGTNGDVIINLGIDTWQTVDGGIRFLADDVAVPAANVSELLAGGTYLNIHSTNNPGGEVRGQVTFPATMGSGGGILNDQGSVTILNSSISDNVASRAGGGIESNVGTTTLSGVNLDRNIAGASGAATPGNGGGLHITGAGNATISGGTVNDNRAGREGGGLWNGSGVMTVNGTTISDNTASGPAADDGGGGIFNNGGDLQLTSVSIANNTADGASSSGGGILNLGGSLSVVDSSITGNEANRAGGGIETTGGSTVSITNSAIDFNSLVAATVAPGNGGGIHIGGDGAVTVSGGSVSDNEAIEGGGLWNSSAGTLTVDGTTVSGNTAVAGGGIYNDAAAADADQTFSLDFIPLNGSSVTGTGSVTVSSPTATTRTIRVVIDAEGLQDVSAFGGLHVAHIHGQFAGNATRPVLEQGDGPFFDGDGGAANGFPPTASVPPSLANDDGRTIADGFLDFLEGRPQYGPVVLNLTSVQLRDASATSSNPPEGVPPLGHFLALVGGGDIDPAALFPSGTEFDLDTTYTFDLTNADEARQFNNIAPAGLREIVLHGQTVDTAISDAIDAVAMGTAPSGVDLGDGSSFRITAPVGVSLITPVSGGVTVTNASVSGNIATGDDLAEGGGGIHNSGSLSVTDSDITGNSATGSAGSGGGIWNGGIASISDSTINVNVANRAGGGIEATDTSTTTLVGVSLNANVAGPDGTAAPGNGGGLHVSGAGTTTIADSSIVDNVAAREGGGLWNGSGVMTVFNSDINQNVASGDSAVHGGGGIFNSGGNLQISQSEITRNFAEGSSGSGGGLFNLDGTVSVTDTVISRNVANRAGGGIEDNSGQSLSLLRVQLTGNDAGSSPGNGGGLHLTGDGTVQIDASLIARNSADNEGGGLWNSASGTISVSQSTISNNLSGSGGGVFNDGSGGDISLNNSTIANNFATGSGGGLATEGGSLTISSATIAYNTAPSGGGIEVSGGDVDLSQTLIASNNATVGPNISGTVTSSGNNLIADTTDAVVDGTSASDLTNVDARIGVLTDNGGLTPTIALLAGSPAINAGVAMAGDVDQRGVSRPQGGQADIGAFESDLAGTASLTLVAVDSELTEGDSGMNNFTFRVTRSGSVDGELMFDFRAFGSGNNPASVGDFTTTSQLPAGTVTFADQQAEVDFMISILGDNDVEATETFTVQISNPSGGANIAVDSATATITNDDVAPAPTLSITAADGDELEGNADDAIFTFVVNRSSAVGNAAVDFAVVGTGTDAATADDFVGAVLPSGTLNFVDGESSQTISIPVAGDDQTENDETFSVTLSNAAAPFVIQTATAAGTIRNDDMDPVTLPPLVSIAGTDSDKAEGDTGTSVLSFTVTRSANTDGVATVDYTVTGSGTNAANADDFAGGVFETGTVTFADGESTQTILINVAGDTLVEPDETFDVTLSNASTSVVLQNGVASGVIRNDDVSDTTSSFAIAATDSDRNEGDTGTTPFTFTVTRSGSLDSAAMIDYSVAGTSSANASASDFGGTLPTGTVVFDAGQSTGVVTVNVSGDMVVEPSEQFTVTLVNAAAGNVIATPSAIGTIRNDDSSVIIESRVIAPLDVARAHSIPASTMPTAIIFRVVSPTTISVVPIGAVSFTDNVRILDDDLFDIATYVDGFASADASELGFHAVIFEASTTDRLYSIRSSAGPNALQGQPKTNLLQPTDTDGDSQTSPADALAVLNALASQAEANRGNGAQGESAALIDSEFYVDVNRDGELTPSDVLVVLNHLSDQANANQASGEQLPSDFLGSPSSDADDTAVRDEALALLDSSDSVDNGIDEVAAGQSSPIELDTIDRIFAGDDESEQDLVDDELELLSR

Crispr_ID: NZ_CP036526_3

• CRISPR_ID: NZ_CP036526_3
• CRISPR_location: 7478642-7478733
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP036526_3

Consensus_repeat	Method
AGCTTGGCGAACAATCCGCCACCGCT	CRISPRCasFinder

spacers of NZ_CP036526_3

>3.1|7478668|40|NZ_CP036526|CRISPRCasFinder
GCAAGTCGCTGGTTCTGGAGTGCTGCATCCGCGTGCTTTT

CRISPR arrays and Neighbor proteins around NZ_CP036526_3

CRISPR arrays

The CRISPR arrays of NZ_CP036526_3

>merge|NZ_CP036526|3|7478642-7478733|CRISPRCasFinder
AGCTTGGCGAACAATCCGCCACCGCTGCAAGTCGCTGGTTCTGGAGTGCTGCATCCGCGTGCTTTTAGCTTGGCGAACAGTCCGCCACCGCT

>NZ_CP036526|3|3|7478642-7478733|CRISPRCasFinder
AGCTTGGCGAACAATCCGCCACCGCT	GCAAGTCGCTGGTTCTGGAGTGCTGCATCCGCGTGCTTTT
AGCTTGGCGAACAGTCCGCCACCGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036526.1|WP_145421300.1|7482809_7483403_+|DinB-family-protein	unknown	unknown	gnl|CDD|378981
NZ_CP036526.1|WP_145421296.1|7477803_7478037_-|hypothetical-protein	unknown	unknown	gnl|CDD|235571
NZ_CP036526.1|WP_145421302.1|7485033_7486263_-|DUF1559-domain-containing-protein	unknown	unknown	gnl|CDD|284919
NZ_CP036526.1|WP_145421288.1|7468280_7469096_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187630
NZ_CP036526.1|WP_145421289.1|7469141_7469741_+|redoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239267
NZ_CP036526.1|WP_145422600.1|7481255_7481447_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421303.1|7487220_7488012_+|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl|CDD|176804
NZ_CP036526.1|WP_145421293.1|7472735_7474163_+|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|180579
NZ_CP036526.1|WP_145421294.1|7475407_7476310_-|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl|CDD|119439
NZ_CP036526.1|WP_145421306.1|7489945_7491010_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421292.1|7471846_7472455_+|30S-ribosomal-protein-S4	unknown	unknown	gnl|CDD|235411
NZ_CP036526.1|WP_145421301.1|7483599_7484955_+|hypothetical-protein	unknown	unknown	gnl|CDD|366080
NZ_CP036526.1|WP_145421299.1|7481446_7482799_+|Trk-system-potassium-transporter-TrkA	unknown	unknown	gnl|CDD|236541
NZ_CP036526.1|WP_145421304.1|7488134_7489103_+|deoxyhypusine-synthase	unknown	unknown	gnl|CDD|376661
NZ_CP036526.1|WP_145421298.1|7479348_7480041_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421291.1|7470891_7471560_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213222
NZ_CP036526.1|WP_145421295.1|7476532_7477726_+|hypothetical-protein	unknown	unknown	gnl|CDD|293767
NZ_CP036526.1|WP_145421305.1|7489406_7489949_+|hypothetical-protein	unknown	unknown	gnl|CDD|227305
NZ_CP036526.1|WP_145421290.1|7469931_7470861_+|beta-hydroxylase	unknown	unknown	gnl|CDD|238362
NZ_CP036526.1|WP_145421287.1|7466059_7468033_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|225114

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036526.1|WP_145421300.1|7482809_7483403_+|DinB-family-protein	gnl|CDD|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	4.76968e-08
NZ_CP036526.1|WP_145421296.1|7477803_7478037_-|hypothetical-protein	gnl|CDD|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0.0018172
NZ_CP036526.1|WP_145421302.1|7485033_7486263_-|DUF1559-domain-containing-protein	gnl|CDD|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	9.20378e-59
NZ_CP036526.1|WP_145421288.1|7468280_7469096_+|SDR-family-oxidoreductase	gnl|CDD|187630	cd05372, ENR_SDR, Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR. This bacterial subgroup of ENRs includes Escherichia coli ENR. ENR catalyzes the NAD(P)H-dependent reduction of enoyl-ACP in the last step of fatty acid biosynthesis. De novo fatty acid biosynthesis is catalyzed by the fatty acid synthetase complex, through the serial addition of 2-carbon subunits. In bacteria and plants,ENR catalyzes one of six synthetic steps in this process. Oilseed rape ENR, and also apparently the NADH-specific form of Escherichia coli ENR, is tetrameric. Although similar to the classical SDRs, this group does not have the canonical catalytic tetrad, nor does it have the typical Gly-rich NAD-binding pattern. Such so-called divergent SDRs have a GXXXXXSXA NAD-binding motif and a YXXMXXXK (or YXXXMXXXK) active site motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.00771e-128
NZ_CP036526.1|WP_145421289.1|7469141_7469741_+|redoxin-domain-containing-protein	gnl|CDD|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	3.56086e-94
NZ_CP036526.1|WP_145421303.1|7487220_7488012_+|Fpg/Nei-family-DNA-glycosylase	gnl|CDD|176804	cd08970, AcNei1_N, N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases. This family contains the N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases. It belongs to the FpgNei_N, [N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII)] domain superfamily. DNA glycosylases maintain genome integrity by recognizing base lesions created by ionizing radiation, alkylating or oxidizing agents, and endogenous reactive oxygen species. They initiate the base-excision repair process, which is completed with the help of enzymes such as phosphodiesterases, AP endonucleases, DNA polymerases and DNA ligases. DNA glycosylases cleave the N-glycosyl bond between the sugar and the damaged base, creating an AP (apurinic/apyrimidinic) site. Most FpgNei DNA glycosylases use their N-terminal proline residue as the key catalytic nucleophile, and the reaction proceeds via a Schiff base intermediate. This family contains mostly actinomycetes and includes Mycobacterium tuberculosis Nei1 (MtuNei1). MtuNei1 recognizes oxidized pyrimidines such as thymine glycol (Tg) and 5,6-dihydrouracil on both double stranded and single stranded DNA, it has a strong preference for the 5R isomer of Tg. In addition to this domain, enzymes belonging to this family contain a helix-two turn-helix (H2TH) domain and a zinc-finger motif.	8.22802e-51
NZ_CP036526.1|WP_145421293.1|7472735_7474163_+|dihydrolipoyl-dehydrogenase	gnl|CDD|180579	PRK06467, PRK06467, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP036526.1|WP_145421294.1|7475407_7476310_-|WecB/TagA/CpsF-family-glycosyltransferase	gnl|CDD|119439	cd06533, Glyco_transf_WecG_TagA, The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common antigen (eca) synthesis. B. subtilis TagA plays a key role in the Wall Teichoic Acid (WTA) biosynthetic pathway, catalyzing the transfer of N-acetylmannosamine to the C4 hydroxyl of a membrane-anchored N-acetylglucosaminyl diphospholipid to make ManNAc-beta-(1,4)-GlcNAc-pp-undecaprenyl. This is the first committed step in this pathway. Also included in this group is Xanthomonas campestris pv. campestris GumM, a glycosyltransferase participating in the biosynthesis of the exopolysaccharide xanthan.	6.09459e-77
NZ_CP036526.1|WP_145421292.1|7471846_7472455_+|30S-ribosomal-protein-S4	gnl|CDD|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	9.17342e-89
NZ_CP036526.1|WP_145421301.1|7483599_7484955_+|hypothetical-protein	gnl|CDD|366080	pfam00404, Dockerin_1, Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.	0.000557884
NZ_CP036526.1|WP_145421299.1|7481446_7482799_+|Trk-system-potassium-transporter-TrkA	gnl|CDD|236541	PRK09496, trkA, Trk system potassium transporter TrkA.	3.21601e-139
NZ_CP036526.1|WP_145421304.1|7488134_7489103_+|deoxyhypusine-synthase	gnl|CDD|376661	pfam01916, DS, Deoxyhypusine synthase. Eukaryotic initiation factor 5A (eIF-5A) contains an unusual amino acid, hypusine [N epsilon-(4-aminobutyl-2-hydroxy)lysine]. The first step in the post-translational formation of hypusine is catalyzed by the enzyme deoxyhypusine synthase (DS) EC:1.1.1.249. The modified version of eIF-5A, and DS, are required for eukaryotic cell proliferation.	1.81412e-28
NZ_CP036526.1|WP_145421291.1|7470891_7471560_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	8.04941e-95
NZ_CP036526.1|WP_145421295.1|7476532_7477726_+|hypothetical-protein	gnl|CDD|293767	cd16148, sulfatase_like, uncharacterized sulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	9.40934e-06
NZ_CP036526.1|WP_145421305.1|7489406_7489949_+|hypothetical-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	4.20155e-06
NZ_CP036526.1|WP_145421290.1|7469931_7470861_+|beta-hydroxylase	gnl|CDD|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	1.75216e-12
NZ_CP036526.1|WP_145421287.1|7466059_7468033_-|GAF-domain-containing-protein	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	4.56752e-135

Protein sequences

>NZ_CP036526.1|WP_145421296.1|7477803_7478037_-|hypothetical-protein
MYNEVAPVSYESAVVSSDAGYDLQPGETLVPGSVQTISTGEATSSSDAAAPAEAAEAPAAEATDAPPAPKPDANTDI
>NZ_CP036526.1|WP_145421295.1|7476532_7477726_+|hypothetical-protein
MSKTNQSKTKLIVLTLDAFAPSALGCYGSSWNSTPAIDALAAGGCVWDRLITNNTDATATLEQWMQQDDWMESWKPMGSIELLSDSQKAISLAAKTNFDQLFLIDPVDQSQENGVAEDLESTQFAQLIAAAVERLGEDDDWSVLWLHSDFLRTCWDAPRWLVDAEPLAEWDDEPLDAAETLEAEMLESNQESTDSLDDLPYVFDQTSPPEIQLKADEHPDLIATWMRTYGCQVRLVDELLRVLVTATADDDVTIVLAGTSGISLGQNGWIGYQAGPLRSCHIGVPMIVAGVGPTRIPQVRDASIVPDTIAKLSQAECQLTDVDQWSHHEDVYQPRVVSRRGSTEHAITTPKWFFVEQKNDSHRLYLKPDDINDFNDISRLRSDVVDELSQNADSDGA
>NZ_CP036526.1|WP_145421294.1|7475407_7476310_-|WecB/TagA/CpsF-family-glycosyltransferase
MQPFPPNQFSSEAVVGPSTPVVVPVVHPAPTSDSASPTTAPSINRDQVVVWDVPFDVVSLTQSIQRIGELIERRQPSYAITANLNYVMLHANDPSMRPITEQADLIVADGQPIVWRSRLAETQLPERVAGSEMIYDLAEAASQKGWKIYFLGGEEGVAAECAKRLVAKYPGLQIAGVESPPFRNLNDQEQAAQDARIQESGADILLVAFGQPKGERWIYDNYQRLGVPVSIQLGASFDFVAGTAIRAPKMWQKIGMEWFYRMVNDPGRMIPRYASNAWFLVKALCKDWHSQVKRWGMDVA
>NZ_CP036526.1|WP_145421293.1|7472735_7474163_+|dihydrolipoyl-dehydrogenase
MHSSVVVLGGGPGGYAAAFLAADEGLEVTIVEAEPRLGGTCLLRGCIPSKALLHVAKVIHEVDELGKEWGVEYSGKPKIDIDKVRARKDKVIDTLTGGLGNLAKRRKVKVIRARGSFVNSTTLKLEGDHESIPEGGQITFDHCVLATGSVPAMPPVFDIGSDRVMDSTGALNLVDIPETMLVIGGGYIGLEMGSVYAQLGSKVTVVELAENLLPGADKDLVKPLAKRIKALCEDRVLLNTKVGSLAENGNKVDVTFEGPGKFGTESFDRVLVSIGRRPVTRGLGLENTQVEVNDRGFVVCDKQQKTADPHILAIGDVAGDPMLAHKATHEGRVAAEVIAGKNSAFDAVAIPAVVFTDPEIAWAGLTEEEAKQAGRKVDVEVYPWAASGRAQALGITDGLTKWLVDPETHRVLGCGIVGSGAGELIAEAVLAIEMGCEVHDITDSVHPHPTLSETLMNAGEVHFGTATEIYKPKKK
>NZ_CP036526.1|WP_145421292.1|7471846_7472455_+|30S-ribosomal-protein-S4
MARYTGPKARVNRRLGTLIYETAGAARALDRRNTPPGMHVRGRRPSNYGMALMEKQKIKHYYGLGERQLRRYFDAVGRKAGNTGELLLLMCERRLDNVVRRVGFTKTRPQARQGVAHGHFRVNGVKVTKPSYMLRPGDIVEVRDRENLKNVYRGVIANAAPDALDWVTFDSENLKATILGLPGPSDISLPVDANAVVEFLSR
>NZ_CP036526.1|WP_145421291.1|7470891_7471560_+|ATP-binding-cassette-domain-containing-protein
MATLKVDHLAKSYPMAGESLHVLTDVSMELSGGDSLAIVGPSGCGKSTLLQILGTLDQPDSGSVLIDNANPFELNESQLAAFRGKQIGFIFQDHHLLPQLSVMENVLVPTLAVGKPSAEDLSRAGELLEAVGLASRTGHLPSELSGGERERVAIARALLMQPTLILADEPTGNLDRTTADSVTQLLLELQKSSGAILITVTHSDTLAAAMDSQRVLEDGKLV
>NZ_CP036526.1|WP_145421290.1|7469931_7470861_+|beta-hydroxylase
MPYLQDLTLRLAMGASQIDREVRDRHANWLLSQQRDDGGFAGREGDSDPYYTAFGLRALWILDALDQSIGDRAAAFLRSRLTAKESIIDMISLIFGAAICELSVGSVVIDDDDLVWRQNIANLLGTLRTDDGGFAKTPEGRAGSTYQTFLSLLCHELIEIEPAEPNRLIDFIGSQAHPDGGYLEIRAAKRAGVNPTAAAIGTLKTLGQLNRVDHTDTIDFLGEMQSDEGGLSANTRIPFADLLSTCTGLITLTDLDAAGEVDVRAAERYAMSMQSPDGGFVGFALDQTADVEYSFYGVATLALCKLATS
>NZ_CP036526.1|WP_145421289.1|7469141_7469741_+|redoxin-domain-containing-protein
MVRTVSTMLPLGTQAPDFSLPNPEGKTVALSDYAGKKAVLVMFVCNHCPYVKHVADQLKVLADDYMAQGVGVVAISSNDADKYPDDSPEAMAKEKAERGYAFEYLFDGDQSVAQAYAAACTPDFFLFDGDMKLAYRGQLDSSRPKMDPPKPVTGEDLRAAIDAVLAGDSPTENQIASLGCNIKWKEGNEPKYFNPNGTA
>NZ_CP036526.1|WP_145421288.1|7468280_7469096_+|SDR-family-oxidoreductase
MQFEGKKGLILGVANDHSIAWAIAKQIMDAGGECGFTHLPDRPDDERQRNRRRVSQLTDKYENAKFLIPMDASKDEDIKSAFDHTAKEFGKIDFMLHSMAFADREDLKGDTVDTSRDGFKLAMDISVYTLLACTAAAKPLMNPGGAIATMTYFGGEKCVPGYNVMGICKAALDATVRYLAYDMGPHGVRVNALSAGPIRTLAGRAAGVEEMLSMYEHMAPMGRNVTHEEVGRTGAFLLSSMSDGISGDILHVDGGYHAMGSPGRLLDQLKK
>NZ_CP036526.1|WP_145421287.1|7466059_7468033_-|GAF-domain-containing-protein
MAEANDVNSAVTAEIFEILQQELSREQFRATALPLLLSQITGQTPGDGATPCGGIVRQVQSQWQTDLWVGKSTTLPEDEISDAIDRSAISLTDQWCVAPLPSLTTDDDLPLSIATASALVVRLDGQPAAQSHIQRTTQITSSVLSRIDQRDRRKLRIEQLTAVLNASIDWQRLDDDEKLLHAIADTATELLDCQRASIFLWDKRRKKLIGRPALGIDGGVLEVADSVGIVGEVLLSGEPKLWSADADDEARINRKVDKKTEFQTDSLLAVPMQGGHRGDVIGVFEAINHNNGSFGAFDAAVLSDLATHASVAIEGLRARRTLAQSRDRLVDDAASATKLIGDHPSIQSVRTSAGKVAKTDLSLLILGRNGTGKEVLAQHVHYESNRRNGPFIAVNCAALVESLLESELFGHEKGAFTDANQTRVGKFELANGGTLFLDEVGDMSPGGQAKLLRVLEEKVVVRVGGSQTIPVDVRVIAATNQPLEQLIAERRFREDLFFRLNVVSLTLPSLHQRGDDVLLLAEHFMQHFCYHIGRQVPTLDASARKAMLSHPWPGNVRELRNTIERLCYLTSEDVITAADLTLNTSAASRINAASTSVDASQFPDELTDATRVFQVTHIENAIARSGGNMTDAAASLGLHRSNLYRKMRQLDMNADEE
>NZ_CP036526.1|WP_145421298.1|7479348_7480041_-|hypothetical-protein
MHSHTSNMAKMMARPAISTGSTSRFSSATGLSAVIKAWKTPVLATFCLFVMGCGKAEVAQTPAATTSGSSGLVSAGVTTTSPTDVVSQFLDQVRRGGANSNAGQFLTKKAQSELQRIGRSVQPIGSPDAHFDVIQAVEVPDEENAMLVESLWTEPNADGTKLKFQVVWSVEKESTDWRISGLAILQEGSEAPEVVDFENGTLMAQLLSDEPAAGTDNQSQAAAPSDGLNR
>NZ_CP036526.1|WP_145422600.1|7481255_7481447_+|hypothetical-protein
MLSISPTYLLHYLPLIVAISLVFGATRHEDTALILKHSFHTARWITGFMAFIFVVLAFISWLI
>NZ_CP036526.1|WP_145421299.1|7481446_7482799_+|Trk-system-potassium-transporter-TrkA
MRVLMLGGGTVGHWLADMLCRKRHDVTVIDIDPNIVRRINSELDVKAIVGSAAQSTVLFQGDVLSTDICLAVTGVDEVNIVAASMAKALGARRSIARVYAPAFSDLSTFDYRQHFNIDSLLSLEQLSAVTLARAIRNPDAIPLEHFARGQLEVYEMDVCPSSDAVGKKLRELKLSGGMRVGSIQREGRKWLASAEDELHVGDRISLIGMPEAVEAARSNFSTTSDRRKQQRIMIAGGGETGFHLARLLSSPDYRLTLLERDLDRCELLAKLLPDATIVHANANRRSVLEDEGGGTADFFVACTGSDESNIMAGVEARELGASRVMAVVERPDYANVVGKLGIDRVVSEREVVARQILGFLNEGAVISQTRLPNGKIGVYELEVSDRTKVTCATLADLPLSGRCLIMGIQREGFIRVPNADDILHAGDIIVALIDLDHVDEILSLFNSKSS
>NZ_CP036526.1|WP_145421300.1|7482809_7483403_+|DinB-family-protein
MKPPQESSLASRRPADSEFTEPYHRDLVNRLDGPCATTVLTDQMYWLCELASSISTLQIDTVHAPYSWTVRQVFEHCADAERVFGYRMLRIAAGDQTNLPSWDENAYAESRFGLGNFTHIVTELGALRKANVMLLRRIIPGCWDKTGFVDEKEISLRAIAWITAGHLHHHLEIVEKRCEITVDRKMPVEKPTGQPAG
>NZ_CP036526.1|WP_145421301.1|7483599_7484955_+|hypothetical-protein
MHQALHRPIRLERLETRDLLAGPDSGFDSSLAVPLPFEQAIEGRDFAIATLQSNASHQGPLLYSFSTDPNTSIGILDDAPDDGIDFRFLNSNGDPLYGSAYSRNISFESFTEYVFADAGDYYLQIDNAADQTDVDGKVQLINHAGFPVAVDPIVTDGAIAPIFAVARDYAGNYSALDLPTNTLADVTFDSATLGLAAGLEINDIALPDQIDVDSAGSLHWAGDWIVLPSIQRDQNQLRRIQTGDQTIELIGGHPDQNPIDRYDVDGSGQVTPADALRVINHLAQYGDQELSLIVESAAYFVDVSGDDVATPLDILKVLGRLSEQTAFSASGESLQIEADNLEASPTASALSQLPRTVAVGGDRSPEFTEPDEPKFDDLSWKSRASDSAFAGSPNPSSTTRSRQDSIRDAESEGYIESIGTAAVDEVLRNDGFEPLGFQFRPNGIPPTQGPG
>NZ_CP036526.1|WP_145421302.1|7485033_7486263_-|DUF1559-domain-containing-protein
MNWKSPPRRQSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNFKQIGLAIHNYHSAYKRLPRHHAGTWVDGAPANQHNAMRLSIFVGLSPFMEQQGLWEQIKNPSVSVVNSGAAIPTPTGQWPSMGPEPWQDEYVPWMTEVPTLRCPSDPGVGLPAFGRTNYAASLGDSTELMSSGAVGIDANNQLVRNNATLASRARAGCRGAFVARQDMRFRDILDGLSNTMIAGEIVTDLGDNDNRSAASINNGSDNIREESDHCQHDGLVSPERPRFWSNGSDGGNAPTLAGADEGRGFRWADAGSVYSSVNNILPPNRELCMGDSAAGPGTVSVGSRHQGGAHILMGDGAVIFITDSIEAGDIHHENVWLGGTGHSAPGSQSPYGLWGAMATRASGEVISEQLNQ
>NZ_CP036526.1|WP_145421303.1|7487220_7488012_+|Fpg/Nei-family-DNA-glycosylase
MPEGHKTHFFAREHSQLLAGQVLKVTSPQGRFRGDARKVSGKILAQVTALGKHMFYEFDSGQIIHIHLGRYGKFRNLACPPPAPVGQVRLRMIGDENTIDLNGPTTCRVIDDELRQQVANKLGPDPLAGGRKADAWEKIQKSKKPIGAILLDQSVIAGIGNIFRAEILHDVGLSPDIRGCDLPRAKFDQLWRSTRRLMKVGLKYGKIVTVTAKQAGMPIAKVQGKERFCVYGRKNCAVCDHPVDTIELASRKLYRCPSCQKVR
>NZ_CP036526.1|WP_145421304.1|7488134_7489103_+|deoxyhypusine-synthase
MNVSQFLERHFRHFNARETLAAAKAYKDFFEGDNPGTMMVTLAGAMSTGELGLSLAEMIRQGKVHAITCTAANLEEDIFNLIAHDEYRIVENWRALSADDEQSLLDAGFNRVTDTCIPETVMRHIESKLLGYWQTHAASGDSLMPCEYMFMLLDDEELKQHYQIPREDSWVAAAKDVGIPIFTPGFEDSTLGNIFAARVYEGVVDNHGAVVTGTAQMERLIGWYLEQSAIGPIGFFQIGGGIAGDFPICVVPLIRQDLQKDIPLWAYFCQISDAVTSYGGYSGAVPNEKITWEKLSVECPKFMIQSDASIVAPLVFAYVLGW
>NZ_CP036526.1|WP_145421305.1|7489406_7489949_+|hypothetical-protein
MRHHRSAVTLLEVSIVLLIVGLTAAVAVPRFNLTMRGIHSRAAAIQIAADIDYVRRTAINRGRSATLTFSPNGQGYASDDVDFPDRVGRKLRVDLAETFDSAVFANAQFDGIVVLDSQSITFDLEGTPHVGSSKLQTGLIVISSAGTATEYIQIDAGTGTVHIYSEGDDLANATGGGAGS
>NZ_CP036526.1|WP_145421306.1|7489945_7491010_+|hypothetical-protein
MNRTHRPIRRAYTLIELIAAMIATTVLLSSLAATIVLSTNMLETPTAQSEAWHDREIADRIVADLRYSHSVDETSLAGFTVTKPSVTTAATESVSYQFGQDGLTRNIDSQSPYVLDQQSPSHTFTVDGFTAPTYIAANTPVRVRSSATAVTTNWANSISVDLPAGCQDGDVLFMAISARSPNSISISPWGWNLLYFLGSNNLRLIVAYRLHDASQSSTTQINFNSGAATAAVTILAIENASLNNPDNWSSSDSGYAWSFLSGTHPGVLEPSTGTLPQHLNLQIYAADGDPWSLYGDTLGVASYADVAQSTTGSSSIGIVVRNGTQPNLANPPSAWQRSSGRWLQAGIRLGGPTE

Crispr_ID: NZ_CP036526_4

• CRISPR_ID: NZ_CP036526_4
• CRISPR_location: 7496801-7497856
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 14 spacers
• Cas_protein_info: cas1,cas2,cas3,csb2gr5,csb1gr7,WYL

Consensus repeat of NZ_CP036526_4

Consensus_repeat	Method
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	PILER-CR
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CRISPRCasFinder
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CRT

spacers of NZ_CP036526_4

>4.1|7496837|37|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
CCAATGATTCTGGCTGGCTTCTTGCACTGGACTCATG
>4.2|7496910|37|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
CCAGGCGTGACGCTGATCACTTCGCGAGGGATTTGCA
>4.3|7496983|37|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
CTGCACTCCTGTTGCGATGCTCACACGCCGGGACCAC
>4.4|7497056|36|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
GCCGCCGCGATTGTCTTGATTCACTTCGCCAAACGT
>4.5|7497128|38|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
CGTATCATGATCAAATCCAACGAAGCCGCAGTGGGTAG
>4.6|7497202|37|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
ATGGCCCTTCGTAGCCTGATACACCGTTGCTGATGAT
>4.7|7497275|36|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
ACTTGGGACACTGGATCAATCACGCTTGACGCCGCC
>4.8|7497347|38|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
GCCTCTGGCGATCCGTTTGCATCGACGCACTTGCCGAC
>4.9|7497421|37|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
CTGTGTGGTAGTAGCCGCAACAGACTTGCTTTGTGTT
>4.10|7497494|36|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
CCGCGGCTTTCCGTTTTGATTCGCTGACGGCCTCTG
>4.11|7497566|36|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
AGAAGGGCTGTTGATGCACCCGAAAGGCATACCACG
>4.12|7497638|36|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
ATCACCACCACCGCGGGCGAACCGGTCAAAGGCGTA
>4.13|7497710|35|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
AAGAAGGGCGGCTGGGACTTGATTTTATGTGACGT
>4.14|7497781|40|NZ_CP036526|PILER-CR,CRISPRCasFinder,CRT
TTGTCGTTGGTTTGTACTGCTCGCGATCGAAAGTCAAATC

CRISPR arrays and Neighbor proteins around NZ_CP036526_4

CRISPR arrays

The CRISPR arrays of NZ_CP036526_4

>merge|NZ_CP036526|4|7496801-7497856|PILER-CR,CRISPRCasFinder,CRT
GCTCCAACGAGGCCGCGTTCGGATGAACGCGGAAAGCCAATGATTCTGGCTGGCTTCTTGCACTGGACTCATGGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGCCAGGCGTGACGCTGATCACTTCGCGAGGGATTTGCAGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGCTGCACTCCTGTTGCGATGCTCACACGCCGGGACCACGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGGCCGCCGCGATTGTCTTGATTCACTTCGCCAAACGTGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGCGTATCATGATCAAATCCAACGAAGCCGCAGTGGGTAGGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGATGGCCCTTCGTAGCCTGATACACCGTTGCTGATGATGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGACTTGGGACACTGGATCAATCACGCTTGACGCCGCCGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGGCCTCTGGCGATCCGTTTGCATCGACGCACTTGCCGACGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGCTGTGTGGTAGTAGCCGCAACAGACTTGCTTTGTGTTGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGCCGCGGCTTTCCGTTTTGATTCGCTGACGGCCTCTGGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGAGAAGGGCTGTTGATGCACCCGAAAGGCATACCACGGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGATCACCACCACCGCGGGCGAACCGGTCAAAGGCGTAGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGAAGAAGGGCGGCTGGGACTTGATTTTATGTGACGTGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAGTTGTCGTTGGTTTGTACTGCTCGCGATCGAAAGTCAAATCGCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG

>NZ_CP036526|4|1|7496801-7497856|PILER-CR
GCTCCAACGAGGCCGCGTTCGGATGAACGCGGAAAG	CCAATGATTCTGGCTGGCTTCTTGCACTGGACTCATG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CCAGGCGTGACGCTGATCACTTCGCGAGGGATTTGCA
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CTGCACTCCTGTTGCGATGCTCACACGCCGGGACCAC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	GCCGCCGCGATTGTCTTGATTCACTTCGCCAAACGT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CGTATCATGATCAAATCCAACGAAGCCGCAGTGGGTAG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ATGGCCCTTCGTAGCCTGATACACCGTTGCTGATGAT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ACTTGGGACACTGGATCAATCACGCTTGACGCCGCC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	GCCTCTGGCGATCCGTTTGCATCGACGCACTTGCCGAC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CTGTGTGGTAGTAGCCGCAACAGACTTGCTTTGTGTT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CCGCGGCTTTCCGTTTTGATTCGCTGACGGCCTCTG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	AGAAGGGCTGTTGATGCACCCGAAAGGCATACCACG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ATCACCACCACCGCGGGCGAACCGGTCAAAGGCGTA
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	AAGAAGGGCGGCTGGGACTTGATTTTATGTGACGT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	TTGTCGTTGGTTTGTACTGCTCGCGATCGAAAGTCAAATC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG

>NZ_CP036526|4|4|7496801-7497856|CRISPRCasFinder
GCTCCAACGAGGCCGCGTTCGGATGAACGCGGAAAG	CCAATGATTCTGGCTGGCTTCTTGCACTGGACTCATG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CCAGGCGTGACGCTGATCACTTCGCGAGGGATTTGCA
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CTGCACTCCTGTTGCGATGCTCACACGCCGGGACCAC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	GCCGCCGCGATTGTCTTGATTCACTTCGCCAAACGT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CGTATCATGATCAAATCCAACGAAGCCGCAGTGGGTAG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ATGGCCCTTCGTAGCCTGATACACCGTTGCTGATGAT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ACTTGGGACACTGGATCAATCACGCTTGACGCCGCC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	GCCTCTGGCGATCCGTTTGCATCGACGCACTTGCCGAC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CTGTGTGGTAGTAGCCGCAACAGACTTGCTTTGTGTT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CCGCGGCTTTCCGTTTTGATTCGCTGACGGCCTCTG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	AGAAGGGCTGTTGATGCACCCGAAAGGCATACCACG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ATCACCACCACCGCGGGCGAACCGGTCAAAGGCGTA
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	AAGAAGGGCGGCTGGGACTTGATTTTATGTGACGT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	TTGTCGTTGGTTTGTACTGCTCGCGATCGAAAGTCAAATC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG

>NZ_CP036526|4|1|7496801-7497856|CRT
GCTCCAACGAGGCCGCGTTCGGATGAACGCGGAAAG	CCAATGATTCTGGCTGGCTTCTTGCACTGGACTCATG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CCAGGCGTGACGCTGATCACTTCGCGAGGGATTTGCA
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CTGCACTCCTGTTGCGATGCTCACACGCCGGGACCAC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	GCCGCCGCGATTGTCTTGATTCACTTCGCCAAACGT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CGTATCATGATCAAATCCAACGAAGCCGCAGTGGGTAG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ATGGCCCTTCGTAGCCTGATACACCGTTGCTGATGAT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ACTTGGGACACTGGATCAATCACGCTTGACGCCGCC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	GCCTCTGGCGATCCGTTTGCATCGACGCACTTGCCGAC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CTGTGTGGTAGTAGCCGCAACAGACTTGCTTTGTGTT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	CCGCGGCTTTCCGTTTTGATTCGCTGACGGCCTCTG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	AGAAGGGCTGTTGATGCACCCGAAAGGCATACCACG
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	ATCACCACCACCGCGGGCGAACCGGTCAAAGGCGTA
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	AAGAAGGGCGGCTGGGACTTGATTTTATGTGACGT
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG	TTGTCGTTGGTTTGTACTGCTCGCGATCGAAAGTCAAATC
GCTTCAATGAGGCCGCGTTCGGATGAACGCGGAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036526.1|WP_145421313.1|7504927_7506559_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl|CDD|274005
NZ_CP036526.1|WP_145421307.1|7491006_7491696_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421311.1|7498047_7500162_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP036526.1|WP_145421305.1|7489406_7489949_+|hypothetical-protein	unknown	unknown	gnl|CDD|227305
NZ_CP036526.1|WP_145421309.1|7493122_7493734_+|hypothetical-protein	unknown	unknown	gnl|CDD|185680
NZ_CP036526.1|WP_145421303.1|7487220_7488012_+|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl|CDD|176804
NZ_CP036526.1|WP_145421325.1|7508606_7508855_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421323.1|7507923_7508142_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145422601.1|7493753_7495367_-|amidophosphoribosyltransferase	unknown	unknown	gnl|CDD|223112
NZ_CP036526.1|WP_145421306.1|7489945_7491010_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145421327.1|7508875_7509241_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP036526.1|WP_145421308.1|7491818_7493087_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036526.1|WP_145422602.1|7500201_7500492_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP036526.1|WP_145422603.1|7506693_7507866_-|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	gnl|CDD|378223
NZ_CP036526.1|WP_145421304.1|7488134_7489103_+|deoxyhypusine-synthase	unknown	unknown	gnl|CDD|376661
NZ_CP036526.1|WP_145421302.1|7485033_7486263_-|DUF1559-domain-containing-protein	unknown	unknown	gnl|CDD|284919
NZ_CP036526.1|WP_145421330.1|7509249_7510272_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NZ_CP036526.1|WP_145421310.1|7495599_7496751_+|glutamate-5-kinase	unknown	unknown	gnl|CDD|235460
NZ_CP036526.1|WP_145421332.1|7510409_7511306_-|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl|CDD|223669
NZ_CP036526.1|WP_145421312.1|7500803_7504931_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl|CDD|274235

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP036526.1|WP_145421330.1|7509249_7510272_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	2.3e-40	133.1	0.0
NZ_CP036526.1|WP_145421311.1|7498047_7500162_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	2.8e-108	356.4	0.0
NZ_CP036526.1|WP_145421312.1|7500803_7504931_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	3.3e-103	340.7	7.3
NZ_CP036526.1|WP_145421313.1|7504927_7506559_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	1.2e-76	253.3	1.6
NZ_CP036526.1|WP_145422602.1|7500201_7500492_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.3e-21	71.4	0.0
NZ_CP036526.1|WP_145422603.1|7506693_7507866_-|type-I-U-CRISPR-associated-protein-Cas7	csb1gr7	pfam09617_csb1gr7_CAS-I-U	9.6e-35	114.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036526.1|WP_145421310.1|7495599_7496751_+|glutamate-5-kinase	gnl|CDD|235460	PRK05429, PRK05429, gamma-glutamyl kinase; Provisional.	1.08134e-161
NZ_CP036526.1|WP_145421305.1|7489406_7489949_+|hypothetical-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	4.20155e-06
NZ_CP036526.1|WP_145421309.1|7493122_7493734_+|hypothetical-protein	gnl|CDD|185680	cd02165, NMNAT, Nicotinamide/nicotinate mononucleotide adenylyltransferase. Nicotinamide/nicotinate mononucleotide (NMN/ NaMN)adenylyltransferase (NMNAT). NMNAT represents the primary bacterial and eukaryotic adenylyltransferases for nicotinamide-nucleotide and for the deamido form, nicotinate nucleotide. It is an indispensable enzyme in the biosynthesis of NAD(+) and NADP(+). Nicotinamide-nucleotide adenylyltransferase synthesizes NAD via the salvage pathway, while nicotinate-nucleotide adenylyltransferase synthesizes the immediate precursor of NAD via the de novo pathway. Human NMNAT displays unique dual substrate specificity toward both NMN and NaMN, and can participate in both de novo and salvage pathways of NAD synthesis.	2.66271e-09
NZ_CP036526.1|WP_145421303.1|7487220_7488012_+|Fpg/Nei-family-DNA-glycosylase	gnl|CDD|176804	cd08970, AcNei1_N, N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases. This family contains the N-terminal domain of the actinomycetal Nei1 and related DNA glycosylases. It belongs to the FpgNei_N, [N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII)] domain superfamily. DNA glycosylases maintain genome integrity by recognizing base lesions created by ionizing radiation, alkylating or oxidizing agents, and endogenous reactive oxygen species. They initiate the base-excision repair process, which is completed with the help of enzymes such as phosphodiesterases, AP endonucleases, DNA polymerases and DNA ligases. DNA glycosylases cleave the N-glycosyl bond between the sugar and the damaged base, creating an AP (apurinic/apyrimidinic) site. Most FpgNei DNA glycosylases use their N-terminal proline residue as the key catalytic nucleophile, and the reaction proceeds via a Schiff base intermediate. This family contains mostly actinomycetes and includes Mycobacterium tuberculosis Nei1 (MtuNei1). MtuNei1 recognizes oxidized pyrimidines such as thymine glycol (Tg) and 5,6-dihydrouracil on both double stranded and single stranded DNA, it has a strong preference for the 5R isomer of Tg. In addition to this domain, enzymes belonging to this family contain a helix-two turn-helix (H2TH) domain and a zinc-finger motif.	8.22802e-51
NZ_CP036526.1|WP_145421332.1|7510409_7511306_-|prolyl-oligopeptidase-family-serine-peptidase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	0.000340401
NZ_CP036526.1|WP_145422601.1|7493753_7495367_-|amidophosphoribosyltransferase	gnl|CDD|223112	COG0034, PurF, Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism].	8.13401e-135
NZ_CP036526.1|WP_145421327.1|7508875_7509241_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.83904e-10
NZ_CP036526.1|WP_145421330.1|7509249_7510272_-|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.17035e-35
NZ_CP036526.1|WP_145421311.1|7498047_7500162_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	3.04682e-113
NZ_CP036526.1|WP_145422603.1|7506693_7507866_-|type-I-U-CRISPR-associated-protein-Cas7	gnl|CDD|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	1.5652e-54
NZ_CP036526.1|WP_145421304.1|7488134_7489103_+|deoxyhypusine-synthase	gnl|CDD|376661	pfam01916, DS, Deoxyhypusine synthase. Eukaryotic initiation factor 5A (eIF-5A) contains an unusual amino acid, hypusine [N epsilon-(4-aminobutyl-2-hydroxy)lysine]. The first step in the post-translational formation of hypusine is catalyzed by the enzyme deoxyhypusine synthase (DS) EC:1.1.1.249. The modified version of eIF-5A, and DS, are required for eukaryotic cell proliferation.	1.81412e-28
NZ_CP036526.1|WP_145421302.1|7485033_7486263_-|DUF1559-domain-containing-protein	gnl|CDD|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	9.20378e-59
NZ_CP036526.1|WP_145421313.1|7504927_7506559_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl|CDD|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	1.43781e-64
NZ_CP036526.1|WP_145422602.1|7500201_7500492_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.56218e-20
NZ_CP036526.1|WP_145421312.1|7500803_7504931_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	3.07736e-65

Protein sequences

>NZ_CP036526.1|WP_145421310.1|7495599_7496751_+|glutamate-5-kinase
MPAPNTHVSRTQVIQNAQSVIVKVGTRVLTTAEGKLDRNRVNLLAAGLCRIAQTGRQTIMVSSGAVGAGIGKLGLDARPSGLSQLQAVAAVGQTDLIQAYESAISASGRHAAQVLLTRADLRRRTGYLHVRNALSQIHSFGAIAVVNENDSVAVGELMTTFGDNDRLAAELSGLLNNALLIILSDIDGLYDGSPSDPDSKCIDVVDSLDDSIFALAQDRTSTVSKGGMASKLAAAQIATSYGHSAIIGPGRDDTVLDKIMAGEKIGTLFVANDKSIRGRRRWIGNAAAVAGTLHLDAGAARAVRQTGSSLLAIGIKQVDGTFKRGSVVAIVDDQGNELARGLCNYPSDEVEKILGQASDQIAEILGHCPYENVVHRDNLTLNP
>NZ_CP036526.1|WP_145422601.1|7493753_7495367_-|amidophosphoribosyltransferase
MSEIHHECGVAAIYHMSGCGRSPMCTDEGPRQISRLLPRMLLDIQNRGQLAAGMTTYSSDRPNLLRTRKDVGTVTEVFRLNHRAKVEALMKTYAGSAAIGHVRYATCGQDDRNYAQPFERKHIHKRKWFSFCFNGQLSNYGLLRERLLADGDHHLSLDTDTEIMLHEFGRILSNADGRMDWIDVLKQTTEGFDGAYSLALLTAEGEMIVARDPLGVKPMCYVHEGPLFAAASESVALLNLGFENEQIKSLPPGHAIIIDPKTGFRMERFAPERTPAHCFFEWIYFANVASTLDDRSVYMSRTHLGEELARAERKLDMVPLDDPDTIIVPVPDTSKAAADAMAYELSIPCREGLIRNRYAGRTFIEGGRARKAKAATKYTPLREVLEGKRIILVEDSIVRSTTMNVLLDRIRDVGGAKEIHVRVACPPIVAPCFYGIDMSTIDQLIAPKYFGIDGELTDESQQKLADDLGADTLRYLPVEAIARAIGKPADHLCRACVTGKYPTDIGQHLYQIALDNRGSKVDSQRTYEQLAEVMSQD
>NZ_CP036526.1|WP_145421309.1|7493122_7493734_+|hypothetical-protein
MHVTKQIWQQIADGRQPYHGDVSEQPILFPGSFNPVHQGHRQMAAIASELFDRPVYPEISLVNVDKPDLDFESLGDRVRQTQPLGRVLVTRAPRFIDKAKLFPGSTFVIGADTAIRLDQPGYYDNSLSSRDDAIDQLASLGSTFLVFGRKVEQTLHDAGELNLSASLTRLCRCVPKTRFRNDISSTQIRGAQQRHAQIRNTQI
>NZ_CP036526.1|WP_145421308.1|7491818_7493087_+|hypothetical-protein
MLFTSLIIVAVVTASLSLSTSSTRSELDRINRQSALRLAESELHRIATVLSTDDQWRDSHSNSVYSDWLSLATLSGSTDTGVVSSDRGNARVRYQLFDVDGDLANDAQDEVVVTAHARVGRSHVAVTATLQNAYPPLPILDYSVTTTDDLEIDSPGTLSTNGIVQVADDCKTGTVGVLVAPELQCSGLNLLSVRGDIASADVQLPSHDVVDVYAQAATTIPTNAIPQNAGVLQLQDILLSSNTNPYGAVDATGLYRINAQGNVLRISHCRIDATLVVEDCPRIDLSGGLTWSFPQQADAILVTDGTIRLQNVEPVLDESARGINFNPASTPYRGTSSNSNQTDSFPSELRGIIYAQNHIECDALTDNSRLNITGALICRDLRIYGNVSITSLPELIDWPPVAFADWRPKRFVRGSFRRVATP
>NZ_CP036526.1|WP_145421307.1|7491006_7491696_+|hypothetical-protein
MSTLFPRGIDRDRSTARAHRIDRAGLSLIEVAVSLILVSTILLVSITASANLMRNSNASQSALRAHELAGILLDEISTRALSDGDSDAVFGVESDEDAANRQTFDDVDDYSGYTQTSPTYLNGQSIDGFDTWTIQINVSPAITTASGITTTNDPDDPLRLVTVVCSSPGHQQTGMPLVTRQSILLSAAGDSHPADLSYEKSRQLELTFSPDRKITVVSPLRNHPSPTTN
>NZ_CP036526.1|WP_145421306.1|7489945_7491010_+|hypothetical-protein
MNRTHRPIRRAYTLIELIAAMIATTVLLSSLAATIVLSTNMLETPTAQSEAWHDREIADRIVADLRYSHSVDETSLAGFTVTKPSVTTAATESVSYQFGQDGLTRNIDSQSPYVLDQQSPSHTFTVDGFTAPTYIAANTPVRVRSSATAVTTNWANSISVDLPAGCQDGDVLFMAISARSPNSISISPWGWNLLYFLGSNNLRLIVAYRLHDASQSSTTQINFNSGAATAAVTILAIENASLNNPDNWSSSDSGYAWSFLSGTHPGVLEPSTGTLPQHLNLQIYAADGDPWSLYGDTLGVASYADVAQSTTGSSSIGIVVRNGTQPNLANPPSAWQRSSGRWLQAGIRLGGPTE
>NZ_CP036526.1|WP_145421305.1|7489406_7489949_+|hypothetical-protein
MRHHRSAVTLLEVSIVLLIVGLTAAVAVPRFNLTMRGIHSRAAAIQIAADIDYVRRTAINRGRSATLTFSPNGQGYASDDVDFPDRVGRKLRVDLAETFDSAVFANAQFDGIVVLDSQSITFDLEGTPHVGSSKLQTGLIVISSAGTATEYIQIDAGTGTVHIYSEGDDLANATGGGAGS
>NZ_CP036526.1|WP_145421304.1|7488134_7489103_+|deoxyhypusine-synthase
MNVSQFLERHFRHFNARETLAAAKAYKDFFEGDNPGTMMVTLAGAMSTGELGLSLAEMIRQGKVHAITCTAANLEEDIFNLIAHDEYRIVENWRALSADDEQSLLDAGFNRVTDTCIPETVMRHIESKLLGYWQTHAASGDSLMPCEYMFMLLDDEELKQHYQIPREDSWVAAAKDVGIPIFTPGFEDSTLGNIFAARVYEGVVDNHGAVVTGTAQMERLIGWYLEQSAIGPIGFFQIGGGIAGDFPICVVPLIRQDLQKDIPLWAYFCQISDAVTSYGGYSGAVPNEKITWEKLSVECPKFMIQSDASIVAPLVFAYVLGW
>NZ_CP036526.1|WP_145421303.1|7487220_7488012_+|Fpg/Nei-family-DNA-glycosylase
MPEGHKTHFFAREHSQLLAGQVLKVTSPQGRFRGDARKVSGKILAQVTALGKHMFYEFDSGQIIHIHLGRYGKFRNLACPPPAPVGQVRLRMIGDENTIDLNGPTTCRVIDDELRQQVANKLGPDPLAGGRKADAWEKIQKSKKPIGAILLDQSVIAGIGNIFRAEILHDVGLSPDIRGCDLPRAKFDQLWRSTRRLMKVGLKYGKIVTVTAKQAGMPIAKVQGKERFCVYGRKNCAVCDHPVDTIELASRKLYRCPSCQKVR
>NZ_CP036526.1|WP_145421302.1|7485033_7486263_-|DUF1559-domain-containing-protein
MNWKSPPRRQSGFTLVELLVVIAIIGILVGLLLPAVQAAREAARRMSCSNNFKQIGLAIHNYHSAYKRLPRHHAGTWVDGAPANQHNAMRLSIFVGLSPFMEQQGLWEQIKNPSVSVVNSGAAIPTPTGQWPSMGPEPWQDEYVPWMTEVPTLRCPSDPGVGLPAFGRTNYAASLGDSTELMSSGAVGIDANNQLVRNNATLASRARAGCRGAFVARQDMRFRDILDGLSNTMIAGEIVTDLGDNDNRSAASINNGSDNIREESDHCQHDGLVSPERPRFWSNGSDGGNAPTLAGADEGRGFRWADAGSVYSSVNNILPPNRELCMGDSAAGPGTVSVGSRHQGGAHILMGDGAVIFITDSIEAGDIHHENVWLGGTGHSAPGSQSPYGLWGAMATRASGEVISEQLNQ
>NZ_CP036526.1|WP_145421311.1|7498047_7500162_-|CRISPR-associated-endonuclease-Cas1
MIHNQPDKQPHSDDFASEQASEIDYLPARMVNEFVYCPRLFYLMHVEGQFANSVDTVDGQFVHRRVDSGTGGLDAAATTLAPGGVLHDLMAETIPRDAQDRTDGETEQDHAPKTRRRSKHVQPESLFGDDHADSTDNDMASETDCEPADVEFAGVDSEALELLDRSNACEPSQPDLTEENARDASVAAAAAKIIHRRSVMLSSDTLGVIAKMDLIEASGDAATPVDYKRGRPRQNADGTAGAWLPERVQVALQALVLQDNGYRCDGGVLYFNETRQRVSIALTDELLTQTRHAVDAARALRRSGTIPPPLSDSPKCPRCSLVGICLPDETRRLGLPTGEASDSPASDTISVRPMLTARDERRPVYFNTQGMWIGKQSEVLQAKVEGKIVQQIRLQEINQVNLFGNVQLSTQAIQTMLNLDIPVVYFTQKGYFYGITHSLGVKNIQVRREQFRFADQPTSCLDLARQIVRGKIRNQRTLLMRNHREPSSVTLRELKRLSDHALDAASLASLLGVEGAAGRAYFQSFAGMLKVDCSLESSPGSALSKRRPAFNFLGRNRRPPRDPVNALLSLAYSLLTKDCVVAATAVGLDPYLGFYHQIKPGKPALALDLMEPFRPLIADSVVLTAINNRMVTPEHFLVAGESVVLSKTGRKHFLLAYEQRMDQLVTHPLFDYRVSYRRLLEIQTRLVARLLTGEIPTYPVFETR
>NZ_CP036526.1|WP_145422602.1|7500201_7500492_-|CRISPR-associated-endonuclease-Cas2
MRRIYLVTYDICEARRLRQTFKCLRNWGDHLQYSVFECHLTASDLIRLRGQLADIIHHDEDQVLVIDLGAAATRSESLVQAIGKPYSAMAAPCLVV
>NZ_CP036526.1|WP_145421312.1|7500803_7504931_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MSDSKLNIETFQAFFREVHGHAPYPWQVRMCQEVLQTGWRDFIQLPTGSGKTSVLDIAVFSLAAQADLPPAERTAATRIFFVIDRRIVVDEADRSARKMADHLQQSLFRSDDSASIQVALQLRKLADSDGRVMDEKNRCPLEVHSLRGGFYRTNQWAGSLVQPMIVTSTVDQVGSRMLFRGYGISPMARPLQAALTATDSLLILDEAHTATAMGETVETIRKYQLRQTADSTPIAKPMSIVQMTATLPARANRVAEDRIFRLCKKTDLADNESPLVTRYQTKKPVHLSVAKSAKGKKVLKQLAKDLSVRVQRHLEDGIGSIAIVVNRIATARALHELLNTKRFDIDLHLMIGRMRPIDRDQTARKLQGSLGTNSETENSKPIVVVSTQCLEVGADLDFDRMISEAASLDALRQRFGRLNRGGRAVDCQGEVVIRGDYDLTEAQLDKRIRSNDVDPVYGAALIRTFRWLQSIGDDDRVDFGGSAMDQQWDQLLALNTQVAKNLLIDEPETTTLLPSHVDLLSQTYQFFVPSDDAQSDRKHAITVHPDPDVGVFLHGRQSRETDVLICWRADLAEVKTVDGSKQFVTIDQRHLTATVSEAPPTSPECMAISIRTVKEFLSGQSLSLGDADQAFVADVKQEDDFIALGSRPVIWRGPDESVVCTNTSQIRPGDTLVMPVSAGGWSQLGHVPSNIPDPAVTRIDADNSEQIVSLLQVDVADQAALRSSWKPQVRLYPLQENAGLLPSGTIKRMRDRETSEESSSIGFQFVGELKRIANWLVDSGQTPQVGQHSVIISAKKRLVRRDVLKLTDRESVESANLDFDDANSASSDVPILLRDHLCRVRNRAKRLGETIGLGDLATTMGRAGELHDLGKADPRFQSVLFGGSTREAWLRRSLLAKSSRAARTQYDRRRDHQRAGLPTNFRHELLSFQLVDHLNLSNDPLLLHLIAAHHGHGRPWMPPCQDDDPPPVDLHSIGIEQVIDDRNEAVDALSRAAIASRFWRIQQQYGAWGTAYLESVLRIADQQISREESEGRHDQNDGPAFVIKAGSTSTKADAGGLCLTGIEADNPLGFLATLGLFRIINDAFEMPVQLYWDVHDGAWRPFLIGPEPINAQQIEKIACDHITTDIAAALNKFDELEPDAKGAGKITACPKRFHAVANELLGKYLIDPRQNRLDCDIAAALGNECSQKRSAKERVIEHSELYMTKGSGHQRMLDLMRVIREQTTWEHIEKTLFSPWAYDDVGRGRSLRWDPAEDRPYAHRWKNPSSDPAMTMLGANYLAIEALSFFPTALVGSRTGALSLQTTAFKRIVRETCFSWPVWTIPMTIDAVKSLLHSSENHFADPNDFRLSQHGVAIVKRVRRVRNDKYFNFSHVESV
>NZ_CP036526.1|WP_145421313.1|7504927_7506559_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MEFTNQRFPVFTIAIQFLTQRVVAANASKHSSVEWPIHPARLFMSLAAAHYENDPTPPERKTLEWLEALPPPSIVAPVASIRETQTVFVPINDKLTGLSQRSKQPRQFPSAFVGDHPARFTWEVEIPKEHLDSLRSLAGKLVRIGHSSSLVHCWIEAEPAETDDASMERWNHVHRANGSSESVRVPSAGLLKSLDRSFNGEAIDQFAELTLTARDAETTKEKNAAKKELKERFPGGLPDSRRPFVGTTAVYQRESVSDETDQTLTTLFDPVLIAMTRIDGPALGLESTLEVCGMLRNAVLSKVGSSAPSWITGHDADGSSTEKVHLALVPLPFIGGSVDLRGCKEREYADGHLLGVGIVLPRDLTDRDKATGLGEFLVDEFGNSIDQQLTLGRNGVWSIRREDRMRPPKALTPETWSRSSHVWATATPIVLDRHPKTDRQKDPGGWRQEVGDIIGRSCRHIGLPQPKSIRVEKHGFLPGVPSASPSRTGFPLMKHSDGKTRRMQTHALIEFASPVQGPVILGSGRFRGYGFCKPVNVKGQVKS
>NZ_CP036526.1|WP_145422603.1|7506693_7507866_-|type-I-U-CRISPR-associated-protein-Cas7
MNYKDLSVAVSGSACAFRGRTRLQPADGVGGKVFPPTHLNGAYAIEKRVVEGRDAPIDCVLLDSVQSHANRCEEALQLAIDREQIEMPLVEVDFSDADLINPVARITALEAPHRISDAILRDSELDGTAFRKSDLGRRMDYASLKNATPLLDLSPHSLLFGIWDSTGPRGGLGVKFQRSLVGEIIGYDISVGKKTASRIDPLQIVSAVPVKETKDNDWDLAKEKEKGAIKPSAINHGNIPPTIEEGGVTMAYAEHSVVISLPAIRRLRFPIDGEYTRERDQAGQSLVAAIGVLSVALATEQGFDLRSRCLLWPETKVTMDLLDQPGSDPKPFDLDSETAIAIYNDAVAAVQKAGLPWRTERVVLKPSQKLVKLVRASQEKATNDPEAVDA
>NZ_CP036526.1|WP_145421323.1|7507923_7508142_-|hypothetical-protein
MSSPAIEQAIRQIYVDHPAAVEPILTSRVLREDFVRSVQHLVAGATEDEVLQHLVRLRKRGADKGGLPRKTK
>NZ_CP036526.1|WP_145421325.1|7508606_7508855_+|hypothetical-protein
MPLYFFHWTEDIIEHLTLNGVSPDDFETVVMDEASEVTTSRSTGRPVRIGFTDDGRLLLCVFDWIDDQETEIEPRTAYEIHA
>NZ_CP036526.1|WP_145421327.1|7508875_7509241_+|helix-turn-helix-domain-containing-protein
MLKRDRENIYPRMTPQERSAMELAIAEETAGMAQNIAAIGPAVARLESERRTFAALVAELRAAREAAGISLSEMATRTGIQKSALSRLENSKAPNPTLSTLQRYAAAIDMTLNVSLQPSRN
>NZ_CP036526.1|WP_145421330.1|7509249_7510272_-|WYL-domain-containing-protein
MSESAGSIGTIQRQLSLLRLLSSRRLGVTADELKSELAVSLKTVRRDLVRLQEVGFPLSVSIEDHNRQRWKLDGDSITGAALAFDEAYALVLLAGSLGSLANTPIGQAAQSAVKKLRSGLSENVIRYCDRYGQMMSLMHPRSVDYSDKSDLIDELIRGHEERKNVFIAYHSRSSTESLTYPISPYAFRRYQNALYVIGYSEQHSEVRLFKLDRISDASISEFPFVMPSHAEIEDHFKDSIGIFGGNPVVVQIRFSPGAARAVQESKWHDSQQLATNADGSVTAMYRIAINPELHGWILSFGADAKVLSPPSLADEIRTQSLQIARQYQAANMEVTDDDGK
>NZ_CP036526.1|WP_145421332.1|7510409_7511306_-|prolyl-oligopeptidase-family-serine-peptidase
MISCQPIPMNLIKRLLFVLLTCLFVSAGSLAAQDAVPADDLWYTKKTDWHGHDQLHFRHADADCYLIKPTKALPGNPWIWRVRFPGFHAEMDVELVGQGFHLAYMDVANQFGCPNVIKRAETFYDRLVSEHDLNRKVVLEGVSRGGLFVYNYAAMHPDHVAAIYCDTPVLDFNSWPRGKGPVGKYTGVGHSASWQQCLKVYGLTDAQAATYDKLPIHHAAIIAKANIPVMHIVSENDRVVPPIENTYVLRDRLKDLGHEMKLIVVPEGTEKSNGHHFTHPEPNTVIQFITTHGQPSPK

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP036526_1	1.3|15105|25|NZ_CP036526|CRISPRCasFinder	15105-15129	25	MG945288	UNVERIFIED: Microviridae sp. isolate 291-1702, partial genome	3633-3657	3	0.88
NZ_CP036526_1	1.2|15045|25|NZ_CP036526|CRISPRCasFinder	15045-15069	25	NZ_CP020910	Rhizobium etli strain NXC12 plasmid pRetNXC12d, complete sequence	11062-11086	4	0.84
NZ_CP036526_1	1.2|15045|25|NZ_CP036526|CRISPRCasFinder	15045-15069	25	NC_048124	Vibrio phage 1.224.A._10N.261.48.B1, partial genome	41525-41549	4	0.84
NZ_CP036526_1	1.3|15105|25|NZ_CP036526|CRISPRCasFinder	15105-15129	25	MN694275	Marine virus AFVG_250M227, complete genome	9099-9123	4	0.84
NZ_CP036526_1	1.3|15105|25|NZ_CP036526|CRISPRCasFinder	15105-15129	25	MN693401	Marine virus AFVG_25M126, complete genome	12999-13023	4	0.84
NZ_CP036526_1	1.3|15105|25|NZ_CP036526|CRISPRCasFinder	15105-15129	25	MT939241	Enterococcus phage 9183, complete genome	29275-29299	4	0.84
NZ_CP036526_1	1.1|14985|25|NZ_CP036526|CRISPRCasFinder	14985-15009	25	NC_047820	Escherichia phage vB_EcoS_ESCO41, complete genome	5747-5771	5	0.8
NZ_CP036526_1	1.1|14985|25|NZ_CP036526|CRISPRCasFinder	14985-15009	25	MT446404	UNVERIFIED: Escherichia virus TH30, complete genome	23478-23502	5	0.8
NZ_CP036526_1	1.3|15105|25|NZ_CP036526|CRISPRCasFinder	15105-15129	25	AP013532	Uncultured Mediterranean phage uvMED DNA, complete genome, group G4, isolate: uvMED-CGR-U-MedDCM-OCT-S28-C22	2354-2378	5	0.8

1. spacer 1.3|15105|25|NZ_CP036526|CRISPRCasFinder matches to MG945288 (UNVERIFIED: Microviridae sp. isolate 291-1702, partial genome) position: , mismatch: 3, identity: 0.88

aaaagcagccaagaaaaaagcagct	CRISPR spacer
agaagcagccaagaaaaatgcagat	Protospacer
*.**************** **** *

2. spacer 1.2|15045|25|NZ_CP036526|CRISPRCasFinder matches to NZ_CP020910 (Rhizobium etli strain NXC12 plasmid pRetNXC12d, complete sequence) position: , mismatch: 4, identity: 0.84

gaagcctgctaagaagaaagcagct	CRISPR spacer
gaagcctgctaagaagaaaacatgc	Protospacer
*******************.**  .

3. spacer 1.2|15045|25|NZ_CP036526|CRISPRCasFinder matches to NC_048124 (Vibrio phage 1.224.A._10N.261.48.B1, partial genome) position: , mismatch: 4, identity: 0.84

gaagcctgctaagaagaaagcagct	CRISPR spacer
aaagcttgctaaaaagaaagcagcc	Protospacer
.****.******.***********.

4. spacer 1.3|15105|25|NZ_CP036526|CRISPRCasFinder matches to MN694275 (Marine virus AFVG_250M227, complete genome) position: , mismatch: 4, identity: 0.84

aaaagcagccaagaaaaaagcagct	CRISPR spacer
gaaagcagccaagaaagaagccgcg	Protospacer
.***************.**** ** 

5. spacer 1.3|15105|25|NZ_CP036526|CRISPRCasFinder matches to MN693401 (Marine virus AFVG_25M126, complete genome) position: , mismatch: 4, identity: 0.84

aaaagcagccaagaaaaaagcagct	CRISPR spacer
aaaaacagccaagaaaaaagctccg	Protospacer
****.****************  * 

6. spacer 1.3|15105|25|NZ_CP036526|CRISPRCasFinder matches to MT939241 (Enterococcus phage 9183, complete genome) position: , mismatch: 4, identity: 0.84

aaaagcagccaagaaaaaagcagct	CRISPR spacer
taaagaagccaagaaaaaagcaatt	Protospacer
 **** ****************..*

7. spacer 1.1|14985|25|NZ_CP036526|CRISPRCasFinder matches to NC_047820 (Escherichia phage vB_EcoS_ESCO41, complete genome) position: , mismatch: 5, identity: 0.8

acgcgtaactaagaagcgcgtaact	CRISPR spacer
ggtggtaactgagaagcgcgtaact	Protospacer
.   ******.**************

8. spacer 1.1|14985|25|NZ_CP036526|CRISPRCasFinder matches to MT446404 (UNVERIFIED: Escherichia virus TH30, complete genome) position: , mismatch: 5, identity: 0.8

acgcgtaactaagaagcgcgtaact	CRISPR spacer
tgttgtaactgagaagcgcgtaact	Protospacer
   .******.**************

9. spacer 1.3|15105|25|NZ_CP036526|CRISPRCasFinder matches to AP013532 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G4, isolate: uvMED-CGR-U-MedDCM-OCT-S28-C22) position: , mismatch: 5, identity: 0.8

aaaagcagccaagaaaaaagcagct	CRISPR spacer
gcccgctgccaagaaaaaagcagct	Protospacer
.   ** ******************