CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042287	Staphylococcus argenteus strain B3-25B plasmid pSALNBL21, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_CP042286	Staphylococcus argenteus strain B3-25B chromosome, complete genome	6 crisprs	cas3,casR,DEDDh,DinG,csa3,WYL	2	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042286_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042286_1

63968-64062

Orphan

Consensus_repeat	Method
TCATTATTTTCCAAATAATAAGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042286_1

>merge|NZ_CP042286|1|63968-64062|CRISPRCasFinder
TCATTATTTTCCAAATAATAAGTGCACTATGGTTTACAGTTGGTCCTTCGCTCCAACTGCATAAGAGCCACTAATTATTTTCCAAATAATAAGTG

>NZ_CP042286|1|1|63968-64062|CRISPRCasFinder
TCATTATTTTCCAAATAATAAGTG	CACTATGGTTTACAGTTGGTCCTTCGCTCCAACTGCATAAGAGCCAC
TAATTATTTTCCAAATAATAAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042286.1\|WP_072467125.1\|65401_66556_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181219
NZ_CP042286.1\|WP_047527522.1\|71445_72147_-\|lytic-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381607
NZ_CP042286.1\|WP_047432173.1\|70691_71180_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP042286.1\|WP_047556017.1\|52185_52356_-\|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl\|CDD\|378908
NZ_CP042286.1\|WP_047555997.1\|68356_70174_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP042286.1\|WP_000259684.1\|58374_59919_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|179543
NZ_CP042286.1\|WP_031787518.1\|60939_61131_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_051975875.1\|75188_75572_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_072467161.1\|54848_57308_-\|fatty-acid-efflux-MMPL-transporter-FarE	unknown	unknown	gnl\|CDD\|225272
NZ_CP042286.1\|WP_000200677.1\|72781_73837_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP042286.1\|WP_000076662.1\|64084_64291_+\|copper-chaperone-CopZ	unknown	unknown	gnl\|CDD\|225328
NZ_CP042286.1\|WP_000935796.1\|54374_54602_-\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|224830
NZ_CP042286.1\|WP_047556014.1\|52368_54363_-\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
NZ_CP042286.1\|WP_072324232.1\|58095_58263_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_014373914.1\|74232_74802_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP042286.1\|WP_047556006.1\|64380_65379_-\|D-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|181499
NZ_CP042286.1\|WP_047433210.1\|60113_60710_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP042286.1\|WP_000665235.1\|57471_58020_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	unknown	unknown	gnl\|CDD\|224228
NZ_CP042286.1\|WP_047556000.1\|67217_67997_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP042286.1\|WP_072467128.1\|61367_63776_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783

Protein	Function_ID	Function_description	E-value
NZ_CP042286.1\|WP_072467125.1\|65401_66556_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181219	PRK08068, PRK08068, transaminase; Reviewed.	6.90474e-140
NZ_CP042286.1\|WP_047527522.1\|71445_72147_-\|lytic-transglycosylase-IsaA	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	5.8177e-06
NZ_CP042286.1\|WP_047432173.1\|70691_71180_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	7.66055e-13
NZ_CP042286.1\|WP_047556017.1\|52185_52356_-\|FeoB-associated-Cys-rich-membrane-protein	gnl\|CDD\|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.000234848
NZ_CP042286.1\|WP_047555997.1\|68356_70174_-\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	5.91722e-85
NZ_CP042286.1\|WP_000259684.1\|58374_59919_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|179543	PRK03137, PRK03137, 1-pyrroline-5-carboxylate dehydrogenase; Provisional.	0
NZ_CP042286.1\|WP_047433210.1\|60113_60710_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.98103e-94
NZ_CP042286.1\|WP_000200677.1\|72781_73837_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.53206e-113
NZ_CP042286.1\|WP_000076662.1\|64084_64291_+\|copper-chaperone-CopZ	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	1.04324e-20
NZ_CP042286.1\|WP_072467161.1\|54848_57308_-\|fatty-acid-efflux-MMPL-transporter-FarE	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	3.41089e-162
NZ_CP042286.1\|WP_000935796.1\|54374_54602_-\|ferrous-iron-transport-protein-A	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	4.82022e-18
NZ_CP042286.1\|WP_047556014.1\|52368_54363_-\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NZ_CP042286.1\|WP_014373914.1\|74232_74802_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.64179e-08
NZ_CP042286.1\|WP_047556006.1\|64380_65379_-\|D-lactate-dehydrogenase	gnl\|CDD\|181499	PRK08605, PRK08605, D-lactate dehydrogenase; Validated.	0
NZ_CP042286.1\|WP_000665235.1\|57471_58020_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.71071e-08
NZ_CP042286.1\|WP_047556000.1\|67217_67997_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.02148e-25
NZ_CP042286.1\|WP_072467128.1\|61367_63776_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0

>NZ_CP042286.1|WP_072467128.1|61367_63776_+|copper-translocating-P-type-ATPase
MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTVQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQKATVNLTTEQAKVDYYPEETDANQLITRIQKLGYDAAVKDKNKDQASRKTKELQHKLIKLIISAALSLPLLMLMLVHLFNMHIPSLFMNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMLRWLSGVTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEIMIPLSDVRVGDTLIVKPGEKIPVDGTIIKGMTSIDESMLTGESIPVEKNVEDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWFTLVTPGIFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDDQTLQLLATAEKDSEHPLAEAIVNYAKDKHMQLTETTSFKAVPGHGIEATIEDHHILVGNRKLMAENDISLPKHISDDLINYEQDGKTAMLIAVNHSLTGIIAVADTVKEHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAAMGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
>NZ_CP042286.1|WP_031787518.1|60939_61131_+|hypothetical-protein
MRILLTGTVAILIILGLVKTIQDQEMTNDTSRQLSDNKDDDKVIHLNNFKNLHAKEFNPSDFF
>NZ_CP042286.1|WP_047433210.1|60113_60710_-|sugar-O-acetyltransferase
MTEKEKMLAQEWYDANFDQDLINERAHAKDLCFELNHTRPSDTKRRKQLIDQLFQTTTDNVSISIPFDIDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHQRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPSNSLAVGNPCKVIREIDNEFSDGQFGGKNG
>NZ_CP042286.1|WP_000259684.1|58374_59919_-|L-glutamate-gamma-semialdehyde-dehydrogenase
MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKEDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDEKIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKAVKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNNFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
>NZ_CP042286.1|WP_072324232.1|58095_58263_-|hypothetical-protein
MRYVILIIMGIVLAIWSFKQLSQSHLDSGFILFFIVYVLCISYFNSDKQTKNKKR
>NZ_CP042286.1|WP_000665235.1|57471_58020_+|fatty-acid-efflux-pump-transcriptional-regulator-FarR
MKETDLRVIKTKKALSSSLLQLLEQQLFQTITVNQICDNALVHRTTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTISDTINNKEDLREIAEFQEEDIEFNKVLKNVCIKIMHDDIKNNRDRIDIDSDVPDNLIFYIYDSLIEGFMHWIKDEKIDWPGEDIDNIFHRLINIKIK
>NZ_CP042286.1|WP_072467161.1|54848_57308_-|fatty-acid-efflux-MMPL-transporter-FarE
MGTFIAKHKWSALIAWVVIVAAIFIPIATNAPKFDNDIKMTGLKSLDTNDKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPSITKDIKKTLNDIKKDDKHIDKISDPYENKQISKDKTTAFADITYDVNQTSLKDGSRDNVKSHLKDLRDNHNVQTELTGTGMTSTDVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGIISLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDHIKGIGLAVGTAGSAVIFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVIFAVISALTLLPALISIFHKRIKVNKLQSKFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPADSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDIVTPPQMSKDNEYALMVVIPKHGPNAESTNDLVHDLRDYNKDAQDKYGYKTEISGQSVINIDMSKKLNEAIPLFASVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLLATLGFTTLVMQDGFMKGLFGIETTGPMLAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYAIKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFIVRMMLIPALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQTSEVENSKEKYDTTFKVHVQDTHVAKGSQLRDETQTIVLDNRTMALYQQVKQHSANPMFLHDALVDYQNKHHLNTQQQTTNIDQLNKNIEKLNQLLEQNLRDKS
>NZ_CP042286.1|WP_000935796.1|54374_54602_-|ferrous-iron-transport-protein-A
MLNVRNGEKNKIYKIKQIDINNMNMLYRLSAFGLTDGSTIKIKQKCLFKGPCIIEINGQQLSIRHCDACCIALEE
>NZ_CP042286.1|WP_047556014.1|52368_54363_-|ferrous-iron-transport-protein-B
MENYCILGNPNVGKTSLFNALTGSYEYVGNWSGVTVEKKVGKLKHHLGELIDLPGIYDLSPISVDETIVTDYLLNNQFTGMINIVDASQLKRNMQLTIQLLELNKPMYIGLNMIDVATKRGIHIDYHKLMKKLKTPIFPVVARTGKGTDHLLGEIKYLGEEAQPHFKLNYGEMIESAIKDICQFIMAETTHSNYEARFIAIQYLLDNIQITKELSQHLLDKLLTIRQRLIQKLNGTTIRREMERIRNQFIDMLLQDIVTYPDDDKQFFSTKLDKILTHKYLGIPIFLGIMWLIFQTTFTWIGTPLSDQLDAFIGGTLTDGVKSAMSYLGLIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSVMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIVMAFLVSTVLTKTVLKNENAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINDSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLIHVIQDQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTVLAVVYPLLTAYVLTLIFYQVGHIFV
>NZ_CP042286.1|WP_047556017.1|52185_52356_-|FeoB-associated-Cys-rich-membrane-protein
MTVMINILIFIAIFGYAFYTLVKFFKRSKQGKCGTCEIDRDCCNTEQRATKHFPGK
>NZ_CP042286.1|WP_000076662.1|64084_64291_+|copper-chaperone-CopZ
MSQEILNVEGMSCGHCKSAVESALNNIDGVTSAEVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
>NZ_CP042286.1|WP_047556006.1|64380_65379_-|D-lactate-dehydrogenase
MTKIKIMSVRDEDMPYIKAWAEKHQVEVDITKDALTDANVETVAGYDGLSLSQQIPLSEQVYKRLNELGIKQIAQRSAGFDTYDLDLASKYNLIVSNVPSYSPNSIAEFAVNQAINVVRHFNQIQTKVRAHDFRWEPSILSKSIKDLKVAVIGTGRIGRVVADIFANGYQSEVIAYDPFPNAKVATYVEYKDTIEEAIEGADIVTLHIPATKYNHYLFDAKLFEHFKKGAVFVNCARGSLVDTKSLLDALDNGLIKGAALDTYEYERKLFPSNQRGKPLNDPLLESLIDREDVILTPHIAFYTEAAVENLIVDALDATLDVLQTGDTKLRVN
>NZ_CP042286.1|WP_072467125.1|65401_66556_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MISNKLAGIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIINHFAEALRIPENQKYGAFHGKESFKQAIVDFYQRQYDVTLDKEEEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPEWSKVNPQILEKTKLIYLTYPNNPTGSTATKEVFDEAIARFKGTDTKIVHDFAYGAFGFDAKNPSILSSENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDIIQALKKYQTHTNAGMFGALQDAAVYALNHYDDFLEEQSNVFKARRDRFEGILAKANLPFVHAKGGIYAWLKTPPGYDSEQFEQFLVKEKSILVAPGKPFGDNGNHYVRISLALDDQQLDEAATRLTDLAYLYH
>NZ_CP042286.1|WP_047556000.1|67217_67997_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNPNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLEQNNTYYYNNNNNTYNTSYNNYSYSNYNNYNRSYQSSNYSYNNYTYNNQASSNYYHTGGSGASYTTTSNNVHVTSTVAPSSNGYASGSNLYTSGQCTYYVFNRVGGKIGSTWGNASNWASAAASAGYTVNNTPKAGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISASQAGSYNFIH
>NZ_CP042286.1|WP_047555997.1|68356_70174_-|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGILIYHLNTQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPDLIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLIFPLVITFLLHRFKPRNIIQTLFVVSLISLGLMMVIHLVTGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKVVASLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFVTLFIIAIAVHPSSLFAKFLSMKPFLIIGKRSYSLYLWHYPIIVFMNSYYVQGQIPAYVYVIEILLTALMAEISYRFIETPIRKNGFKAFAFLPKKKSQFIRTILVILLLIPTITVLAGQFDALGKQHETQKKEKKTEFKTMKKKVDKKDKAKQDDKQKANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGDFTKDQLNELLDSFGKADIYLVSIRVPRNYEGRINKLIYEAAEKRSNVHLVAWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHSSNKK
>NZ_CP042286.1|WP_047432173.1|70691_71180_-|GNAT-family-N-acetyltransferase
MTINVIEYNRSYHEELIGFILSIQKNEFNINIDRNDQPDLENIEQNYLNNGGQFWLAINDQQKIIGTIGLIKLDNNKSALKKMFVDENYRNLKVGKKLLDIVVTTCKENNIDEIYLGTIDKFISAQYFYSKNGFREINQKDLPSSFPKLDVDNRFYYRNLIG
>NZ_CP042286.1|WP_047527522.1|71445_72147_-|lytic-transglycosylase-IsaA
MKKTIMASSLAVALGVTGYAASTGHEAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSDVQSVSYNAQSSNSNVAAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTGTVDQQINAAVKAYNAQGLAAWGF
>NZ_CP042286.1|WP_000200677.1|72781_73837_-|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALIAMKFDLSPLAIAVVSSAAYVGSGAAQFKNGAWVIAGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTRMITTGIGNMVNGFTELQPIIMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNIVKYPILMLPILTTAIVSGLVSAIVGIYGTKESAGFGFIGMVGPINAFKFMHVDSAWLSVLLIVVAFFVVPFLTAWVADIIYRKVFRLYTNDIFKFMG
>NZ_CP042286.1|WP_014373914.1|74232_74802_+|TetR/AcrR-family-transcriptional-regulator
MMENKSIDPRIIRTKQLLVDAFQKVSREKKLSQITVKDITDIATVNRATFYAHFTDKEDILDYTLSVTILKDLNDNLNISNVINEKVLRNIFISIASYMKDVEKSCELNSEAFCHKAHQRINNELEDIFAIMLENSYPDHQRDIIVNSASFLAAGVSGLALHWLNTSQDSADVFIDKNLPFLIHHIAHF
>NZ_CP042286.1|WP_051975875.1|75188_75572_+|hypothetical-protein
MSETDEPMGFEYTHIHIPLMYQNGSKYVLSIGDTKLKLKSKQIMKVIAHSVQQIVYQMKYKNYITQFDDGLNRSHKFGFKQSNNMLFIFAQFNKMSSDKVSFYAQHRHPFISTNFPNTTSTSLLSSN

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Crispr_ID: NZ_CP042286_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042286_2

200919-201000

Orphan

Consensus_repeat	Method
TGTTGGGGCCACCCCAACCTGCATTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042286_2

>merge|NZ_CP042286|2|200919-201000|CRISPRCasFinder
TGTTGGGGCCACCCCAACCTGCATTGCCTGTAGAAATTGGGATCCAATTTCTCTGTGTTGGGGCCACCCCAACTTGCATTGC

>NZ_CP042286|2|2|200919-201000|CRISPRCasFinder
TGTTGGGGCCACCCCAACCTGCATTGC	CTGTAGAAATTGGGATCCAATTTCTCTG
TGTTGGGGCCACCCCAACTTGCATTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042286.1\|WP_047555881.1\|202237_203476_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|274866
NZ_CP042286.1\|WP_047556306.1\|192265_192694_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_146501828.1\|196455_197067_-\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|224766
NZ_CP042286.1\|WP_000240582.1\|203439_203745_+\|intracellular-adhesion-protein-D	unknown	unknown	gnl\|CDD\|188447
NZ_CP042286.1\|WP_000790912.1\|201512_202073_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376089
NZ_CP042286.1\|WP_014373923.1\|197145_197622_-\|peptide-methionine-(S)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|235497
NZ_CP042286.1\|WP_000185857.1\|199112_199805_-\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP042286.1\|WP_000603478.1\|196011_196371_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_047431969.1\|203741_204614_+\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	unknown	unknown	gnl\|CDD\|188448
NZ_CP042286.1\|WP_047555873.1\|210140_210845_-\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	unknown	unknown	gnl\|CDD\|172156
NZ_CP042286.1\|WP_047555879.1\|204600_205653_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226446
NZ_CP042286.1\|WP_000592598.1\|209385_210144_-\|imidazole-glycerol-phosphate-synthase-subunit-HisF	unknown	unknown	gnl\|CDD\|234996
NZ_CP042286.1\|WP_047555877.1\|205844_207878_-\|YSIRK-domain-containing-triacylglycerol-lipase-Lip1	unknown	unknown	gnl\|CDD\|224001
NZ_CP042286.1\|WP_047555883.1\|199822_200485_-\|capsule-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|226453
NZ_CP042286.1\|WP_031787603.1\|198348_199116_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP042286.1\|WP_078377634.1\|192839_193784_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_000635358.1\|210837_211416_-\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|171871
NZ_CP042286.1\|WP_089418591.1\|193770_195864_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_047555875.1\|208756_209389_-\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	unknown	unknown	gnl\|CDD\|235067
NZ_CP042286.1\|WP_000244263.1\|197624_198128_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326

Protein	Function_ID	Function_description	E-value
NZ_CP042286.1\|WP_047555881.1\|202237_203476_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|274866	TIGR03937, Poly-beta-16-N-acetyl-D-glucosamine_synthase, poly-beta-1,6 N-acetyl-D-glucosamine synthase. Members of this protein family are biofilm-forming enzymes that polymerize N-acetyl-D-glucosamine residues in beta(1,6) linkage. One named members is IcaA (intercellular adhesin protein A), an enzyme that acts (with aid of subunit IcaD) in Polysaccharide Intercellular Adhesin (PIA) biosynthesis in Staphylococcus epidermis). The homologous member in E. coli is designated PgaC. Members are often encoded next to a polysaccharide deacetylase and involved in biofilm formation. Note that chitin, although also made from N-acetylglucosamine, is formed with beta-1,4 linkages.	0
NZ_CP042286.1\|WP_000592598.1\|209385_210144_-\|imidazole-glycerol-phosphate-synthase-subunit-HisF	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	2.6003e-154
NZ_CP042286.1\|WP_146501828.1\|196455_197067_-\|flavin-reductase-family-protein	gnl\|CDD\|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	9.1821e-46
NZ_CP042286.1\|WP_000240582.1\|203439_203745_+\|intracellular-adhesion-protein-D	gnl\|CDD\|188447	TIGR03932, IcaD_partial, intracellular adhesion protein D. Members of this protein family are IcaD (intracellular adhesion protein D), which with catalytic subunit IcaA forms an N-acetylglucosaminyltransferase. In the absence of IcaC, this enzyme forms N-acetylglucosamine oligomers up to 20 in length. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	8.03567e-29
NZ_CP042286.1\|WP_000790912.1\|201512_202073_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|376089	pfam18665, TetR_C_37, Tetracyclin repressor-like, C-terminal domain. IcaR belongs to the tetracycline repressor (TetR) family of proteins, which are involved in a wide variety of gene regulations. It binds to a 42 bp region immediately upstream of the icaA gene. This entry represents the C-terminal domain which is involved in dimerization.	1.78121e-26
NZ_CP042286.1\|WP_014373923.1\|197145_197622_-\|peptide-methionine-(S)-S-oxide-reductase	gnl\|CDD\|235497	PRK05528, PRK05528, peptide-methionine (S)-S-oxide reductase.	2.11465e-105
NZ_CP042286.1\|WP_000185857.1\|199112_199805_-\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.27432e-84
NZ_CP042286.1\|WP_047555877.1\|205844_207878_-\|YSIRK-domain-containing-triacylglycerol-lipase-Lip1	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	1.9447e-81
NZ_CP042286.1\|WP_047431969.1\|203741_204614_+\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	gnl\|CDD\|188448	TIGR03933, Poly-beta-16-N-acetyl-D-glucosamine_N-deacetylase, intercellular adhesin biosynthesis polysaccharide N-deacetylase. A common motif in bacterial biosynthesis of polysaccharide for export is modification that follows polymerization. This model describes a subfamily of polysaccharide N-deacetylases that acts on poly-beta-1,6-N-acetyl-D-glyscosamine as produced by Staphylococcus epidermidis and S. aureus. The end product in these species is designated polysaccharide intercellular adhesin (PIA), and this gene designated icaB (intercellular adhesion protein B). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Cellular processes, Pathogenesis].	3.96346e-149
NZ_CP042286.1\|WP_047555873.1\|210140_210845_-\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	gnl\|CDD\|172156	PRK13587, PRK13587, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Provisional.	1.66832e-165
NZ_CP042286.1\|WP_047555879.1\|204600_205653_+\|acyltransferase-family-protein	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	4.01362e-110
NZ_CP042286.1\|WP_047555883.1\|199822_200485_-\|capsule-biosynthesis-protein-CapA	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	4.28953e-88
NZ_CP042286.1\|WP_031787603.1\|198348_199116_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.11734e-141
NZ_CP042286.1\|WP_000635358.1\|210837_211416_-\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|171871	PRK13142, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	1.85309e-125
NZ_CP042286.1\|WP_047555875.1\|208756_209389_-\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	1.91907e-106
NZ_CP042286.1\|WP_000244263.1\|197624_198128_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.89712e-13

>NZ_CP042286.1|WP_047555883.1|199822_200485_-|capsule-biosynthesis-protein-CapA
MKEKFDLVKLLNILKKNIKLLVILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVAREFDGEYTTTELNSFLKITNQTNSQIITVSVTTGNKSESEKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIISVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVEAQLGLPILGSIQKF
>NZ_CP042286.1|WP_000185857.1|199112_199805_-|polysaccharide-biosynthesis-tyrosine-autokinase
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSSYQDSIISTEIEDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVINSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
>NZ_CP042286.1|WP_031787603.1|198348_199116_-|tyrosine-protein-phosphatase
MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYENSFQHVLVKLAELRTHPEIQALDIKLFPGQEIRITDSILKGLDNGSIQGINRSKYLLIEFPTNEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPELLYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFIASDAHSCDQRPFLMQELFHNNKLKKYTNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF
>NZ_CP042286.1|WP_000244263.1|197624_198128_-|GNAT-family-N-acetyltransferase
MVLRKVIIQDLDQIIALENIGFSPEEAATPEALKSRIEQIQDSFIVAEYNGEVIGYINGPVIKERYISDDLFKNVQTNDSEGGYISVLGLVVAPNYQGQGIAGRLLNYFENLAKNQQRQGITLTCRESLISFYEKYGYRNEGISESCHGGIKWYNLVKDIKIKDDEV
>NZ_CP042286.1|WP_014373923.1|197145_197622_-|peptide-methionine-(S)-S-oxide-reductase
MAVVYVAGGCLWGVEAFFSTIPGIIHTEAGRANGGSSILDGPYDGYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNQQGNDIGEKYRTGLYSCVDKHLTEARQFINRRKDRGQIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHLSKDLLNKYK
>NZ_CP042286.1|WP_146501828.1|196455_197067_-|flavin-reductase-family-protein
MRTFDAQSLSAKENYKLLIGSIIPRPIAFVTTLNQDISVNAAPCSFFNIVNNHPPMIAIAVQRAGGKRKDTALNIERTGDFVVHITDEDNVQDINETAAPLVYGDSELSRTELSLVTSTTIKTPGIQEAKMRFECKLSQIILLGDELDGADLIIGEIVTYHIDDSIYEGDFKINPHGLQAVSRLAGNDYAKLGEIFTINRPEK
>NZ_CP042286.1|WP_000603478.1|196011_196371_+|hypothetical-protein
MILRYATNLKLAKELYQASKPKLQEDKGMIELFEHTFGLQKELVKYVGIAEATTAALYSASFINKNISRLASLSTIGILSVAAYKHFEAGHGKKGAQHALDLLGLATLSLLDTFSCNKK
>NZ_CP042286.1|WP_089418591.1|193770_195864_+|hypothetical-protein
MKTNKLITDLDAIELSSAWNYNQQIDFDDKIKVNNHNYKVIEKVNPTSTGLGYKIYERYDNKKPTGKLIISFDGTDFSDSNDVNTDLRLAGESIPNQLLEAGKVYSDLKQKYSDANSMDASKFQEKYKQHPKDYKGKSITNAGGNSLSGAIAQYLGVLDPGLNVTTTNSAPMPRSITRMARRDANNIHNYHSRSDVLTRINIGGLMYNSMVGKHIFLENGVSTFGALGPAHTGYNFEEKEKLDHFDQDNIINKEVYTSRNGLKIYADMDEHTPIFVWSGDAIGAGTSKIKLDKGHLADLNDYVHGRLTEYVNNIDLKMKDIRTSVERENNNFSQHVNETKDYFKKVIKLNELEGWIHNISNLIRTKIESKADELKGNLRTLRDQDNILDLVGADHIINSIIDFIDKITDKISKFIKYGDDFMEAAFDIVSNTIVKMFVNLSEGFEDGVREEVLAHLNVVIPNIQIIKNQVTNFGDGINDILTQMTHLDDNVMVNNVPINKNATKQTSKPLAESKNLLLNLEIRNKVMEAGLASLASSINILLVPITSKLVNIITLVDACTPTLSNFVGKIEWIASKVPFAKTTAEILKSFKNLVDKLHQQLTDMRLILGELIFTEYIIVEMQDFFKNALLSDSLLRDIKILSANAKGDTDMLETELHAVINAMSQNEGKSVDALKNSTASLKNNLTKLKEQLDKTTH
>NZ_CP042286.1|WP_078377634.1|192839_193784_+|hypothetical-protein
MRKITGFVLCTSLILGGCSFMHKDQTKDIPKTVSVKDYDGKYIGEHKKRNEVFLKKHKDEAIQKYRNYVKDTFGYDCKINLVKPYTNASGFSEKSKTDGLVVVGTVNYDVPFQLRLLFVESDNGVTITTFTPGHENETSAAISAMMYKRYEHEIEQARLKFKSEVEKNGYFAMNEKLQVKQEYNGVVRQYLNFKTPGIEGMDKFKKEFKPLMNKSNSDFNQKFDALLMKHPEIKDQAKTNFIAYYSKNKTRDIVGDYVVTLQKPTNKVMKNYPGIKFMKFYKDSVSPSQLDKNGRLKSEVEEVSTIGGEYNENK
>NZ_CP042286.1|WP_047556306.1|192265_192694_+|hypothetical-protein
MSEKLQLKQEFNGVTRQYLNFRTDSIDDLDKFKKEFKPVMHLKGDAFNQQLQSLINKYPQIQKNMKSEFIAYYDNEKNRETVKNYAWNLQKSINDVMQSYPSTKFVQFYKDDVSPSMVDGNGRLKSDANVISIEGGKYNENK
>NZ_CP042286.1|WP_000790912.1|201512_202073_-|TetR/AcrR-family-transcriptional-regulator
MKNKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNVILVNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSEDIYRQIRDLNQSLSQEIAKFYDESKVTMTNEDFQNLILLFLESWYLRASFSQKFGSVEESKSQFKDEVYSLLNIFLKK
>NZ_CP042286.1|WP_047555881.1|202237_203476_+|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MQFFNFLLFYPVFMSIYWIVGSIYYFFTKEIRYSLKKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKMKENNDFIFVDLQENKGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLLGYHIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
>NZ_CP042286.1|WP_000240582.1|203439_203745_+|intracellular-adhesion-protein-D
MVKPRQREYPTLKSSLNIVRETALVAISCFFWIYCFVVLLVYIGTIFGFHDESINTIRVALNIENTEILNIFESMGIFAIIIFVFFTISLLIQKWQRGRDS
>NZ_CP042286.1|WP_047431969.1|203741_204614_+|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase
MKLRKLIILVLSLLIILPVSTLDTHHVANADDDAPKKLKYKKDSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEDNFHNLDMISKKQLKEMYKTGLWEFETHTDDLHNLSKNNKSKLMKSSDATIIKDINKSEKYLTKNFKKSQNTIAYPYGLMNDKKLPAIKKAGIKYGFSLEEKAVTPDANDYYIPRILISDDAFEHLIKRWDGFHEKD
>NZ_CP042286.1|WP_047555879.1|204600_205653_+|acyltransferase-family-protein
MKKIRLELVYLRAIICTIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTNSSFNKQFVENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFIVQQTFLYYFSNNSAFHDTVLHYYPLSENTLILGWIFYFFLGAYLGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSVMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMIFLTISLLLILGLCIGVGMIFREFYIFRFIIGKQPYKLNINAF
>NZ_CP042286.1|WP_047555877.1|205844_207878_-|YSIRK-domain-containing-triacylglycerol-lipase-Lip1
MRQSQNKYSIRKFSVGASSILIATLLFLSGGHAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENNVNGQQHTENLTKNLHNDKTTSEENHYKIDDLNKDQLRDDKKSSLDAKNIQRDTPDNLSNVNQGLEQNINDGKQSKVASQQQAKEADNSQDSNANNNLTSQSPTKQRPSLNKTEQASQPEIVNETEIEKVQPQQKNQTNDEITNHNFNDEQAVNSKKDVKSLQVSDLKNNQKSPVEPTNDNDNKKELNILKNSAVATLPNKGTKELTAKAKGDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGVYKDWKPGQKIHLVGHSMGGQTIRQLEELLRNGSREEIEYQKQHGGEISPLFKGNHDNMISSITTLGTPHNGTHASDLAGNEALVRQVVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATELNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTNATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKVTDTKQA
>NZ_CP042286.1|WP_047555875.1|208756_209389_-|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE
MTNYIIDFSKGLVPAILQDSRTKQVLMLGYMNQDAFDKTVKDGVVCFYSRSKQRLWTKGETSGHTQRVEDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNDKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
>NZ_CP042286.1|WP_000592598.1|209385_210144_-|imidazole-glycerol-phosphate-synthase-subunit-HisF
MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTIGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSHYDPERKAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFEQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
>NZ_CP042286.1|WP_047555873.1|210140_210845_-|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase
MIELWPAIDLIESTSVRLTEGKYDSEEKMSRSAEESIAYYSEFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKAQIMDYFAAGINYCIVGTKGIQDTEWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVKQLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATPIPVIASGGIRHQQDIQRLASLNVHAAIVGKAAHQPAFWEGLK
>NZ_CP042286.1|WP_000635358.1|210837_211416_-|imidazole-glycerol-phosphate-synthase-subunit-HisH
MIVIIDYGLGNISNVKRAVEHLGYKVVVSNDQNIIEQAETIILPGVGHFKDAMSEIKRLNLDAILAKNTDKKMIGICLGMQLMYEHSDEGDVSGLGFIPGNISHIQTNYPVPHLGWNNLVSQHPMLNQDVYFVHSYQAPMSENVIAYAQYGVDIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND

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Crispr_ID: NZ_CP042286_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042286_3

849699-849944

Orphan

Consensus_repeat	Method
GCACAACTGCATAAGAGCCTCTAATCGCTAAAGC	CRT

3 spacers

The CRISPR arrays of NZ_CP042286_3

>merge|NZ_CP042286|3|849699-849944|CRT
GAACAACTACATAAGAGTCTCTAATCGCTAAAGCGAAAAGTGGGATTAAATGAATACAGTTGGTTTGCATGCGCACAACTGCATAAGAGCCTCTAATCGCTAAAGCTCAAGAGTGTAGAGGAACGCAGTTGGAAGCTAAGGCACAACTGCATAAATCCCTCTAATCGCTAAAGCAAAAAGTGGGATTAAATGAATACAGTTGGTTTGCATGTGCACAACTGCATAAGAGCCTCTAATCGCTAAAGC

>NZ_CP042286|3|1|849699-849944|CRT
GAACAACTACATAAGAGTCTCTAATCGCTAAAGC	GAAAAGTGGGATTAAATGAATACAGTTGGTTTGCATGC
GCACAACTGCATAAGAGCCTCTAATCGCTAAAGC	TCAAGAGTGTAGAGGAACGCAGTTGGAAGCTAAG
GCACAACTGCATAAATCCCTCTAATCGCTAAAGC	AAAAAGTGGGATTAAATGAATACAGTTGGTTTGCATGT
GCACAACTGCATAAGAGCCTCTAATCGCTAAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042286.1\|WP_001200748.1\|844982_845993_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP042286.1\|WP_072467188.1\|839370_839997_+\|DUF443-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700
NZ_CP042286.1\|WP_031787455.1\|842122_842599_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP042286.1\|WP_047433809.1\|857595_858525_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP042286.1\|WP_001788287.1\|843961_844483_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP042286.1\|WP_001819741.1\|846299_846683_+\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP042286.1\|WP_047557072.1\|848820_849456_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP042286.1\|WP_001018678.1\|856278_856653_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP042286.1\|WP_146501706.1\|852712_853513_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP042286.1\|WP_047557074.1\|846679_848341_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP042286.1\|WP_146501704.1\|841417_841954_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP042286.1\|WP_031787460.1\|854319_855036_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_047557076.1\|840267_841206_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP042286.1\|WP_047557070.1\|852009_852729_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP042286.1\|WP_047430290.1\|851004_851955_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP042286.1\|WP_000047659.1\|858706_858931_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP042286.1\|WP_000180234.1\|842638_843934_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP042286.1\|WP_000735552.1\|853648_854155_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_001045431.1\|855203_855992_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP042286.1\|WP_088778563.1\|850018_850858_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563

Protein	Function_ID	Function_description	E-value
NZ_CP042286.1\|WP_001200748.1\|844982_845993_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP042286.1\|WP_072467188.1\|839370_839997_+\|DUF443-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	1.90445e-58
NZ_CP042286.1\|WP_031787455.1\|842122_842599_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.28081e-12
NZ_CP042286.1\|WP_047433809.1\|857595_858525_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	2.01241e-33
NZ_CP042286.1\|WP_001788287.1\|843961_844483_+\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP042286.1\|WP_001819741.1\|846299_846683_+\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
NZ_CP042286.1\|WP_047557072.1\|848820_849456_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	1.43746e-81
NZ_CP042286.1\|WP_146501706.1\|852712_853513_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.02429e-25
NZ_CP042286.1\|WP_047557074.1\|846679_848341_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP042286.1\|WP_146501704.1\|841417_841954_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.58276e-24
NZ_CP042286.1\|WP_001018678.1\|856278_856653_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77929e-26
NZ_CP042286.1\|WP_047557076.1\|840267_841206_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	8.10253e-168
NZ_CP042286.1\|WP_047557070.1\|852009_852729_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	2.37561e-38
NZ_CP042286.1\|WP_047430290.1\|851004_851955_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	9.526e-48
NZ_CP042286.1\|WP_000047659.1\|858706_858931_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.16162e-12
NZ_CP042286.1\|WP_000180234.1\|842638_843934_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.30042e-150
NZ_CP042286.1\|WP_001045431.1\|855203_855992_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.28374e-32
NZ_CP042286.1\|WP_088778563.1\|850018_850858_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.62264e-70

>NZ_CP042286.1|WP_047557072.1|848820_849456_+|endonuclease-III-domain-containing-protein
MLGTDDLYKILYAHLGPQNWWPAENDIEMMLGAILVQNTRWLNAEIALNQIKEHTHFNPKHILELPIETLQSLIRSSGFYKNKSLTIKSLLTWLGRHHFNYQEINERYKDKLRNELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYAKLGYENTKSYEQLKKVITLPNYFTNQDANEFHALLDVFGKYYFRDKDTTNYDFLEPYFKN
>NZ_CP042286.1|WP_047557074.1|846679_848341_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLVEEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVRQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP042286.1|WP_001819741.1|846299_846683_+|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP042286.1|WP_001200748.1|844982_845993_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP042286.1|WP_001788287.1|843961_844483_+|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP042286.1|WP_000180234.1|842638_843934_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVSPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP042286.1|WP_031787455.1|842122_842599_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVRPESQHKGYGTALLNEGLSRFEGKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYQPEMYGEKLDLALMYKVF
>NZ_CP042286.1|WP_146501704.1|841417_841954_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQGLDYQWIDVTQHQFKPIRDVRHTEKSIANYEGDYQEILDKVLASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAQKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTADKPGDVMKDNYALASATEWNQLLQ
>NZ_CP042286.1|WP_047557076.1|840267_841206_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKEVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDGNQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKNQAVAALQELKEQGKIKAIGVSNFTLNQLKEANKDGYVDVVQLEYNLLHRDNEAVLQYCVDHQITFIPYFPLASGILAGKYNENTKFSDHRATRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVIENIKAADIVLSNDEIQYIDELFPIES
>NZ_CP042286.1|WP_072467188.1|839370_839997_+|DUF443-domain-containing-protein
MLLCESKIINKNPKYRIIKYNDEYLMVDIISTWISLFFPFINWFIPKRYVKISREEFENLNIVKPAKKNVFWPVAGISALFAVTLRKYTHLLDIQLDKKLVIAICCITFIGILTFYVRLIKKSSLNIYNTKNKKSKIILIPTLKNVCFTLFGYILFGGLTMLFLNALLSMSYQNIIVYFAWIAVIMGFFLVNIALIIDKNIHAILKNP
>NZ_CP042286.1|WP_088778563.1|850018_850858_+|ABC-transporter-substrate-binding-protein
MSACGNNNEKHDSDKKETSKTPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKTTANKVLSSLEKQGIKVVYVKDAQSINETYDTFKQVGKLTNRDKQAEQLVEETKDNVAKIIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLDKLDAQNIYNDIDGWQAVTKESIIKKNPDILISTESKTKSDYMNIIKKRGGFNKTNAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYKK
>NZ_CP042286.1|WP_047430290.1|851004_851955_+|iron-ABC-transporter-permease
MTFNKTILSWIVILIITSAMYLFWQLGSINDPFNQSILMNVRLPRYFEALLTGMILTVSGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTALWIPIFSVVFSFITLLIVLFITSILSRGYPIRILILCGLMVGALFNSLLYFLILLKPRQLNTIANYLFGGFGDAEYSNVTVITTVFIVGLCAIILILNQLKLLQLGELKSQSLGLNVQIITFIALCLASMMTAINVAYVGIIGFIGMIIPQLIKKWQWRQTLGRQLTLNCIIGGQTMVIADFIGSHVLSPIQIPASIIIALIGIPVLFYMLISQSKQLH
>NZ_CP042286.1|WP_047557070.1|852009_852729_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFSDFEMHFYRYVFPYYDTLYTLEKLSQEGYQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVSPEEIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGDNYGSIY
>NZ_CP042286.1|WP_146501706.1|852712_853513_+|alpha/beta-fold-hydrolase
MDLFTRKDGTSLHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRRIDIHDFADDIVGLLKYLYIEEVALICHEMGGFIGADMSVRYPQHTSSLVLVNPTSIESELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVEDTNEISTKEEIQAVKDVFKRQGISKVYGDVEVPTMIVAGEFGERTTRLEAKEVADLIQHVDFKVYQESSAFPFVEEQEKFVEDATIFINEHHENKHV
>NZ_CP042286.1|WP_000735552.1|853648_854155_+|hypothetical-protein
MKKLLTASIIACSVVLGVGLVNTNAEAASGNSIDTVKQLTKGDQSLEKVKIGESIKDVLTKYKNPMYSYNENGTEHYYEFHTNKGMLLVTTDGKKNDGKVIRVSMMYNDANGPTYQAVKNYVGKAVTHTEYSKVTGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP042286.1|WP_031787460.1|854319_855036_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVNTDIKNSEKQDQDYIEYKGKSPAQIILMIQRNLFALQLNPVIFFILNFILISYLYDKQYVQFQAITGMSLFYCLIIFPMTIVVCLRVSKKNYLRSNKLEMIMGTVIAIISLILIVLQAFNVTWGIIPITNFGHQFFFFVGIILVIVGIFYKHLEFSGIGLLFCQKTIDAMIHNPQTAQVFSLIIWMLLVILVIYFTIRLSSRTRI
>NZ_CP042286.1|WP_001045431.1|855203_855992_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQMKGKGEPIILLHGLDGNLAGFEDLQHQLATSFKVISYDLRGHGKSSKSESYELNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIAAKKDDLIHSFTQLLIKYQDEVAGFNKSEAYILLFSKLFKNQENTMKWYQKQKIYSTKSEDDSAAAIRSLILHQDEPIYMKKRTCVPTLLINGEHDPLIQDKLHFKLEAHFLNVTKKIFDHSGHAPHIEEPEVFLDYYLDFIKSVS
>NZ_CP042286.1|WP_001018678.1|856278_856653_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLTRVNKRITEANNEIEL
>NZ_CP042286.1|WP_047433809.1|857595_858525_-|DMT-family-transporter
MLLLYFLGIIVGMLIPIQTSVNSRLSLYTKSPFYTSLISFSVGTLCLVILNIVINPEVFTTHFYSNQTFNYTWIVGGILGVSFLTGNLLLLPRLGATLTVIATVAGQIIMGVLIDTFGLFGASIHEFNLIKAFGVLLLLFGIILMNQFNKNNLLLVNQNHIILWLVLGFIFGFLPPIQTAINSTLAYNTHSPAFASLVSFSIGTITLFVLTIILNRSLKISTKHKQFGNLKPIYFVGGILGMAFVTANIILMPHLGAALTTIIGMFGQILMGILIDHFGLFGSPKITMTLRKSIGLLSIISGIILLRLF
>NZ_CP042286.1|WP_000047659.1|858706_858931_-|DUF2922-domain-containing-protein
MSKTLELSFKSTSDKPVKLQLPQLNNLVTEQIARDSMNALVGLNILQSNSGAITKVHAAQIVDKTTTVLFEEKK

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Crispr_ID: NZ_CP042286_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042286_4

883431-883516

Orphan

Consensus_repeat	Method
CCAACTTGCACATTAATGTCACCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042286_4

>merge|NZ_CP042286|4|883431-883516|CRISPRCasFinder
CCAACTTGCACATTAATGTCACCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTAATGTCAGCTGACTTT

>NZ_CP042286|4|3|883431-883516|CRISPRCasFinder
CCAACTTGCACATTAATGTCACCTGACTTT	TCGTCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTAATGTCAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042286.1\|WP_146501708.1\|875290_876043_-\|M50-family-metallopeptidase	unknown	unknown	gnl\|CDD\|315961
NZ_CP042286.1\|WP_031787475.1\|887640_887733_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_047557058.1\|881863_883159_-\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_CP042286.1\|WP_000479287.1\|886136_887366_+\|nucleoside-permease	unknown	unknown	gnl\|CDD\|224883
NZ_CP042286.1\|WP_047557060.1\|880257_881325_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|132997
NZ_CP042286.1\|WP_000184751.1\|889841_890846_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP042286.1\|WP_000215397.1\|876279_877044_+\|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl\|CDD\|224833
NZ_CP042286.1\|WP_001103230.1\|877108_877903_-\|teichoic-acids-export-ABC-transporter-ATP-binding-subunit-TagH	unknown	unknown	gnl\|CDD\|184131
NZ_CP042286.1\|WP_001273061.1\|878249_879062_+\|teichoic-acids-export-ABC-transporter-permease-subunit-TagG	unknown	unknown	gnl\|CDD\|224596
NZ_CP042286.1\|WP_047557055.1\|890842_891859_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223682
NZ_CP042286.1\|WP_000954658.1\|874571_875216_+\|metal-dependent-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224240
NZ_CP042286.1\|WP_000832260.1\|881381_881780_+\|glycerol-3-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|173922
NZ_CP042286.1\|WP_047557052.1\|893088_893673_+\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
NZ_CP042286.1\|WP_047430252.1\|879160_880261_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|224799
NZ_CP042286.1\|WP_001044670.1\|887908_888742_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP042286.1\|WP_000894468.1\|873706_874450_-\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NZ_CP042286.1\|WP_000733756.1\|892078_893044_+\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
NZ_CP042286.1\|WP_001062612.1\|893665_894028_+\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	unknown	unknown	gnl\|CDD\|184702
NZ_CP042286.1\|WP_000088638.1\|889012_889810_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP042286.1\|WP_000817961.1\|884041_885769_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055

Protein	Function_ID	Function_description	E-value
NZ_CP042286.1\|WP_146501708.1\|875290_876043_-\|M50-family-metallopeptidase	gnl\|CDD\|315961	pfam13398, Peptidase_M50B, Peptidase M50B-like. This is a family of bacterial and plant peptidases in the same family as MEROPS:M50B.	4.05584e-29
NZ_CP042286.1\|WP_047557055.1\|890842_891859_+\|iron-ABC-transporter-permease	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	2.06569e-79
NZ_CP042286.1\|WP_047557058.1\|881863_883159_-\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	2.20976e-90
NZ_CP042286.1\|WP_000479287.1\|886136_887366_+\|nucleoside-permease	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	1.78285e-143
NZ_CP042286.1\|WP_047557060.1\|880257_881325_+\|glycosyltransferase	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	3.28778e-13
NZ_CP042286.1\|WP_000184751.1\|889841_890846_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	6.15157e-79
NZ_CP042286.1\|WP_000215397.1\|876279_877044_+\|WecB/TagA/CpsF-family-glycosyltransferase	gnl\|CDD\|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	3.79617e-95
NZ_CP042286.1\|WP_001103230.1\|877108_877903_-\|teichoic-acids-export-ABC-transporter-ATP-binding-subunit-TagH	gnl\|CDD\|184131	PRK13546, PRK13546, teichoic acids export ABC transporter ATP-binding subunit TagH.	0
NZ_CP042286.1\|WP_001273061.1\|878249_879062_+\|teichoic-acids-export-ABC-transporter-permease-subunit-TagG	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.24008e-58
NZ_CP042286.1\|WP_000954658.1\|874571_875216_+\|metal-dependent-transcriptional-regulator	gnl\|CDD\|224240	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription].	2.3373e-47
NZ_CP042286.1\|WP_000832260.1\|881381_881780_+\|glycerol-3-phosphate-cytidylyltransferase	gnl\|CDD\|173922	cd02171, G3P_Cytidylyltransferase, glycerol-3-phosphate cytidylyltransferase. Glycerol-3-phosphate cytidylyltransferase,(CDP-glycerol pyrophosphorylase). Glycerol-3-phosphate cytidyltransferase acts in pathways of teichoic acid biosynthesis. Teichoic acids are substituted polymers, linked by phosphodiester bonds, of glycerol, ribitol, etc. An example is poly(glycerol phosphate), the major teichoic acid of the Bacillus subtilis cell wall. Most, but not all, species encoding proteins in this family are Gram-positive bacteria. A closely related protein assigned a different function experimentally is a human ethanolamine-phosphate cytidylyltransferase.	2.10132e-65
NZ_CP042286.1\|WP_047557052.1\|893088_893673_+\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	5.35808e-83
NZ_CP042286.1\|WP_047430252.1\|879160_880261_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|224799	COG1887, TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane].	1.18883e-34
NZ_CP042286.1\|WP_001044670.1\|887908_888742_+\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	2.13657e-76
NZ_CP042286.1\|WP_000894468.1\|873706_874450_-\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	4.97485e-99
NZ_CP042286.1\|WP_000733756.1\|892078_893044_+\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
NZ_CP042286.1\|WP_001062612.1\|893665_894028_+\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	gnl\|CDD\|184702	PRK14484, PRK14484, phosphotransferase mannnose-specific family component IIA; Provisional.	3.47738e-52
NZ_CP042286.1\|WP_000088638.1\|889012_889810_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	7.57943e-137
NZ_CP042286.1\|WP_000817961.1\|884041_885769_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.12354e-163

>NZ_CP042286.1|WP_047557058.1|881863_883159_-|D-alanyl-D-alanine-carboxypeptidase
MKNLISIIITICLIVSIMTPNAQAANSTETPVQVANQYGYAGLSAAYQPTSAINVSQTGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLNDTVTMTNKEYIMSTLPELSNTKLYPGQVWTIADLLQITVSNSSNAAALILANKVSKNTSDFVDLMNNKAKALGMTNTHFVNPTGAENSRLRTFAPTKYKNQERTVTTARDYAILDLHVLKETPKILDFTKQLAPTTHAVTYYTFNYSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKRGKFRINQVIMGAGDYKNLGGEKQRNMMGNALMEQSFDQYKYVKILSKGEQKINGKKYYVENDLYDVLPSNFSKKDYKLVVDDGKVHVDYPRQFINKDYGPPTVDVHQPIIQKANAVAKNMWTEHPIFTIIGGACLVGGLALIIHMLIKLIFRKRK
>NZ_CP042286.1|WP_000832260.1|881381_881780_+|glycerol-3-phosphate-cytidylyltransferase
MKRVITYGTYDLLHYGHIELLRRAREMGDYLIVALSTDEFNQIKHKKSYYDYEQRKMMLESIRYVDLVIPEKGWGQKEDDVEKFDVDVFVMGHDWEGEFDFLKDKCEVIYLKRTEGISTTKIKQELYGKDAK
>NZ_CP042286.1|WP_047557060.1|880257_881325_+|glycosyltransferase
MRLTIIIPTLNNEATIRQLLVSIDSKEHYRILCIDGGSTDQTIPLVEKLQKELKNITLIQLQNASKASCINKGIKEIETTEGHYSDAFIVLNPTSILLPNKLDLLTSTFKNNENIDIVIGQRAIDYHGEWKLNDIDSYIKNNHIVTLSQQPELLSSLTFDNKLLSVKFADLRCDESVENVYNHEMLVKALQKATDIQLVSQLVIGDNQVNEVDFNNVIELYQFSKEIMSVRQRIMEMLLLLEQRLIYSDLVDRQLFNTHLKRYLLLHPEMTETMISLVSDYIMSMQHSDYLSHNMFEIINTVEFLGVNWNKETYEKWREMLIQVGINRPRYRKFLIQLKGRKIVHQTKSILKRLN
>NZ_CP042286.1|WP_047430252.1|879160_880261_+|CDP-glycerol-glycerophosphotransferase-family-protein
MNVLIKRLYHLLIRLLCKIISTQKSNKPHIVFMMTFPEDILPIIKSLNTSLYDVTVLTAPKNKFHLSAINNLNVVEMSNKTLVKQIKALKSAQLIIIDNYYLLLGGYKKAPHQRVIQTWHASGALKNFGLTDNQVDLSNKAMIQQYRQVYQATDFYLVGSPYMAHCFKQSLAARDDQMLYFGIPRINKYFTVDREAIKTQLKEQYGIKNKLALYVPTYREDSADNREINKTYFENELPGYTLLNKLHPSIEVSESDQLTSIDTSTLMLMADLIISDYSSLPIEASLLNIPTIFYVYDESTYDKVRGLNKYYFGIPENYKVYSEADLITAIKANKHTLKPLFKDWHIYNTEHSLPQLLEYIDKMVTK
>NZ_CP042286.1|WP_001273061.1|878249_879062_+|teichoic-acids-export-ABC-transporter-permease-subunit-TagG
MSAIGTVFKEHVKNFYLIQRLAQFQVKIINHSNYLGVAWELINPVMQIMVYWMVFGLGIRSNAPIHGVPFVYWLLVGISMWFFINQGILEGTKAITQKFNQVSKMNFPLSIIPTYIVTSRFYGHLGLLLLVIIACMFTGIYPSIHIIQLLIYVPFCFFLTASVTLLTSTLGVLVRDTQMLMQAILRILFYFSPILWLPKNHGISGVIHEIMKYNPVYFIAESYRAAILYHEWYFMDHWKLMLYNFGIVAIFFAIGSYLHMKYRDQFADFL
>NZ_CP042286.1|WP_001103230.1|877108_877903_-|teichoic-acids-export-ABC-transporter-ATP-binding-subunit-TagH
MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKDFRNKLDESRFVIK
>NZ_CP042286.1|WP_000215397.1|876279_877044_+|WecB/TagA/CpsF-family-glycosyltransferase
MTVEETSNTSKVDILGVNFDNTTMLQMVENIKTFFAHQSTNNLFIVTANPEIVNYATTHQAYLELINRASYIVADGTGVVKASHRLNRSLSQRIPGIELMDECLKIAHVNHQKVFLLGATNEIVEAAQYALQQRYPNITFAHHHGYIDLEDETVVKRIELFKPDYIFVGMGFPKQEEWIMTHEQQFVSTVMMGVGGSLEVFAGAKKRAPFIFRKLNIEWVYRALIDWKRIGRLKSIPIFMYKIAKIKRKNKKSK
>NZ_CP042286.1|WP_146501708.1|875290_876043_-|M50-family-metallopeptidase
MNYLTNFLNTTTELNIYIIVFVAIIYIVIHHFRHKPLLNYLDIILNYIPVLTHEFGHVLFNKIAGGRAKDLVIVTSPRERQQTLQQGFAVTQSRHLAGQWLTTLGGYLMPPLMLLIGLASSHYQIPSIFIFSYLLIFIYFLILTSRKGSPIIVITLISIMLYFILKDDNILAIQMIVTISYQFILGVLLGEILQSSWTIAKLTIQRPSPQWDGSALKDLSHVPIFIYSTIWIIFNLYAVNILLKYTHLIS
>NZ_CP042286.1|WP_000954658.1|874571_875216_+|metal-dependent-transcriptional-regulator
MLTEEKEDYLKAILTNNGDKNFVTNKILSQFLNIKPPSVSEMVGRLEKAGYVETKPYKGVRLTEDGLTHTLDIIKRHRLLELFLIEILKYNWEEVHQEAEILEHRISNLFVERLDSLLNFPETCPHGGVIPRNNEYKEKYVTTILNYEPGDLVTIKRVRDKTDLLVYLSSKDISIGNEVEIVSKDEMNKVIIIKRNDNVIIISYENAMNMFAEK
>NZ_CP042286.1|WP_000894468.1|873706_874450_-|metal-ABC-transporter-ATP-binding-protein
MLETKDLNLFLGNKHVLKNISLSIPVRGEIIGIMGPNGAGKSSLIKSLIGEFNATGTKLLYNKPIQQQLQHITYIPQKAHIDLDFPISVEQVILSGCYKEIGWFRRPNKSARDKLKQLLSDLELETLRHRQISELSGGQLQRVLVARALMSESEVYFLDEPFVGIDFSSEKLIMTKIENLKQQGKLILIIHHDLSKAKQYFDRIILLNQTLRYFGDSEEAMSVTRLNETFMSSTDCSDPSQRSNITC
>NZ_CP042286.1|WP_000817961.1|884041_885769_+|ABC-transporter-ATP-binding-protein
MKRENPLFFLFKKLTWPVGLIVAAITISSLGSLSGLLVPLFTGRIVDKFSVSHINWNLIALFGGIFVLNALLSGLGLYLLSKIGEKIIYAIRSVLWEHIIQLKMPFFDKNESGQLMSRLTDDTKVINEFISQKLPNLLPSIVTLIGSLIMLFILDWKMTLLTFITIPIFVLIMIPLGRVMQKISTSTQSEIANFSGLLGRVLTEMRLVKISNTERLELDNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAIILGFGALEIATGAITAGTLIAMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQEPIEPTEDLEDSKNVLIDDGVLSFEHVDFKYDVKKILDDVSFQIPQGQVSAFVGPSGSGKSTIFNLIERMYEIESGDIKYGLESVYDIPLSKWRRKIGYVMQSNSMMNGTIRDNILYGINRHVTDEELINYAKLANCHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDILLLDEATANLDSESELKIQEALETLMEGRTTIVIAHRLSTIKKAGQIIFLDKGQVTGKGTHSELMASHDKYKNFVVSQKLTD
>NZ_CP042286.1|WP_000479287.1|886136_887366_+|nucleoside-permease
MFLLINIIGLIVFLGIAVLFSRDRKNIQWTSIGILVVLNLFLAWFFIYFEWGQIVVKGAANGIAWVVQSAHAGTGFAFASFINVKMMDMAVTALFPILLIVPLFDILMYFNILPKIIGGIGWLLAKVTRQPKFESFFGIEMMFLGNTEALAVSSEQLKRMNEMRVLTIAMMSMSSVSGAIVGAYVQMVPGELVLTAIPLNIVNAIIVACLLNPVSVEEKEDIIYSLKNNEIERQPFFSFLGDSVLAAGKLVLIIIAFVISFVALADLFDRLINLITGLVAGWIGIKGSFGLDQILGVFMYPFALLLGLPFDEAWLVAQQMAKKIVTNEFVVMGEISKDIASYTPHHRAVITTFLISFANFSTIGMIIGTLKGIVDKKTSDFVSKYVPMMLLSGILVSLLTAAFVGLFAW
>NZ_CP042286.1|WP_031787475.1|887640_887733_+|hypothetical-protein
MFCYYKQHKGDNFSIEEVKNIIAENEMKVN
>NZ_CP042286.1|WP_001044670.1|887908_888742_+|YitT-family-protein
MNKTVKDLILVVLGSFIFAAGVNAFIISGNLGEGGVTGLAIILYYAFHLSPAITNFVVNAVLIAIGYKFLSKRSMYLTILVTVLISIFLSLTESWQVETGNSIVNAIFGGLSVGLGIGVIILAGGTTAGTTILARIATKYLDVSTPYALLFFDMIVVAISLTVIPLDKVLVTVISLYIGTKVMEYVIEGLNTKKAMTIISTNPDKLAKAIDEQIGRGLTILNGHGYYTREEKDVLYVVISKTQVSKAKRLIKNIDKDAFLVIHDVRDVYGNGFLADE
>NZ_CP042286.1|WP_000088638.1|889012_889810_+|ABC-transporter-ATP-binding-protein
MSRLHGQQVKIGYGDSTIINKLDVEIPDGKVTSIIGPNGCGKSTLLKALSRLLAVKEGEVFLDGQNIHTQSTKEIAKKIAILPQSPEVADGLTVGELVSYGRFPHQKGFGRLTEEDKKEIDWAMEVTGTDAFRHRSINDLSGGQRQRVWIAMALAQRTDIIFLDEPTTYLDICHQLEILELVQKLNQEQGCTIVMVLHDINQAIRFSDHLIAMKSGDIVAHGSTEDVLTQEILEKVFNIDVVLSKDPKTGKPLLVTYDLCRRAYS
>NZ_CP042286.1|WP_000184751.1|889841_890846_+|iron-ABC-transporter-permease
MTNRENQTSLKFITYVIGLSILLVIALFISTLLGDAKIQASTILEAVFNYDPTNQQQNVINEIRIPRNIAAVIVGMALAVSGAIIQGVTRNGLADPALIGLNSGASFALALTYALLPGTSFLVLMFAGFLGAILGGAIVLMMGRSRRDGFNPMRIILAGAAVSAMLTALSQGIALAFRLNQTVTFWTAGGVAGTTWTHLKWAIPLIGVALLVILMFSKQLTILNLGESLATGLGQNVTVIRGICLIIAMILAGISVAIAGQVAFVGLMVPHIARFLIGTDYTKILPLTALLGGLLVLVADVIARYLGEAPVGAIISFIGVPYFLYLVKKGGRTI
>NZ_CP042286.1|WP_047557055.1|890842_891859_+|iron-ABC-transporter-permease
MINSNNMRKQWIALVVFSVLLFLGCTWSITSGEYNIPVERFFKTLIGQGDPTDELILLDFRLPRMLITILAGATLSISGAIVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGVGLQTALYGGSITIMSKFDDNQSEFIAAWFAGNIWGDEWPFVIAFLPWIIIIIPYLLIKSNTLNIIHTGDNIARGLGVKLSRERLILFFIAVTLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIALQPGGIPAGIVVAIIGAPYFLYLMYKTKNV
>NZ_CP042286.1|WP_000733756.1|892078_893044_+|dihydroxyacetone-kinase-subunit-DhaK
MKKLINKKETFLTDMLEGLLIAHPELDVVANTVVVKKAKKENGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGIKVETVIVRDDIAVANEEQRRGVAGTVFVHKLAGYLAEKGHSLSDIKTRVEAFLPEIKSIGMAIEPPLVPTTGKYGFDIENDKMEIGIGIHGEKGIHREEMKDVEHIVEALFNELFKEVNYDDVILMVNGMGGTPLSELNIVTKYIQHHLVTRKVNVAKWFVGDYMTSLDMQGFSITILPNKPEYLEAFLAPTTSRYFK
>NZ_CP042286.1|WP_047557052.1|893088_893673_+|dihydroxyacetone-kinase-subunit-L
MNVNDMKTRLLQLEETFKTHESELTELDRAIGDGDHGVNMVRGFSSVKDKIDDSSMQALLKSTGMALMSNVGGASGPLYGFSFVKMASVSKDDMNHQDIITLIKTFAEAISARGKVNLNEKTMYDVVARAAEKLENGETLSLNQLQQLADNTKDMVATKGRAAYFGEESKGYIDPGAQSMVFVLNALIGDENNG
>NZ_CP042286.1|WP_001062612.1|893665_894028_+|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM
MAKIILVSHSKDIANGTKALLQQMAGDVDILALGGLTDGSIGTSFDLIQEALTDLDDDALCFYDIGSSEMNVDMAIEMYDGDYRVIKVDAPIVEGSFIAAVRLSVGGTVDDALAEIKQSF

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Crispr_ID: NZ_CP042286_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042286_5

2322912-2323010

Orphan

Consensus_repeat	Method
CAGTTGATGCGCAGCATCCAACTGTGTTCCTCT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP042286_5

>merge|NZ_CP042286|5|2322912-2323010|CRISPRCasFinder
CAGTTGATGCGCAGCATCCAACTGTGTTCCTCTATTTTTCTACTTTAGTTGTTTGGGGCTCTTATACAGTTGATGCGCAGCATCCAACTGTGTTCCTCT

>NZ_CP042286|5|4|2322912-2323010|CRISPRCasFinder
CAGTTGATGCGCAGCATCCAACTGTGTTCCTCT	ATTTTTCTACTTTAGTTGTTTGGGGCTCTTATA
CAGTTGATGCGCAGCATCCAACTGTGTTCCTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042286.1\|WP_047557498.1\|2329746_2331867_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP042286.1\|WP_031787719.1\|2316345_2317011_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP042286.1\|WP_000019747.1\|2317483_2318464_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP042286.1\|WP_001123296.1\|2311826_2312240_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP042286.1\|WP_001127968.1\|2314952_2315891_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP042286.1\|WP_031788232.1\|2325675_2327481_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP042286.1\|WP_031787716.1\|2312848_2314222_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP042286.1\|WP_000003754.1\|2317161_2317482_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP042286.1\|WP_000808819.1\|2314691_2314922_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_000648735.1\|2332313_2333420_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP042286.1\|WP_146501812.1\|2319777_2321490_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_CP042286.1\|WP_000609031.1\|2321775_2322546_-\|enoyl-ACP-reductase-FabI	unknown	unknown	gnl\|CDD\|236308
NZ_CP042286.1\|WP_047557492.1\|2323739_2324597_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP042286.1\|WP_072324271.1\|2327931_2328147_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_146501814.1\|2333724_2341068_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_CP042286.1\|WP_000220898.1\|2323523_2323610_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_001292149.1\|2331879_2332314_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP042286.1\|WP_047557495.1\|2324664_2325447_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP042286.1\|WP_031788233.1\|2328162_2329713_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP042286.1\|WP_047557488.1\|2318723_2319815_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042286.1\|WP_047557498.1\|2329746_2331867_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.39085e-62
NZ_CP042286.1\|WP_031787719.1\|2316345_2317011_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.35466e-48
NZ_CP042286.1\|WP_000019747.1\|2317483_2318464_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.78579e-109
NZ_CP042286.1\|WP_001123296.1\|2311826_2312240_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	2.01205e-46
NZ_CP042286.1\|WP_001127968.1\|2314952_2315891_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	3.61048e-125
NZ_CP042286.1\|WP_031788232.1\|2325675_2327481_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP042286.1\|WP_031787716.1\|2312848_2314222_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	8.90514e-06
NZ_CP042286.1\|WP_000003754.1\|2317161_2317482_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.00861e-17
NZ_CP042286.1\|WP_000648735.1\|2332313_2333420_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP042286.1\|WP_146501812.1\|2319777_2321490_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.41281e-34
NZ_CP042286.1\|WP_000609031.1\|2321775_2322546_-\|enoyl-ACP-reductase-FabI	gnl\|CDD\|236308	PRK08594, PRK08594, enoyl-[acyl-carrier-protein] reductase FabI.	2.27521e-175
NZ_CP042286.1\|WP_047557492.1\|2323739_2324597_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.54887e-59
NZ_CP042286.1\|WP_146501814.1\|2333724_2341068_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	8.6353e-112
NZ_CP042286.1\|WP_001292149.1\|2331879_2332314_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP042286.1\|WP_047557495.1\|2324664_2325447_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	2.12125e-96
NZ_CP042286.1\|WP_031788233.1\|2328162_2329713_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0

>NZ_CP042286.1|WP_000609031.1|2321775_2322546_-|enoyl-ACP-reductase-FabI
MINLENKTFVIMGIANKRSIGFGVAKVLDQLGAKLVFTYRKDRSRKELEKLLEQLNQEEPKLYQIDVQKDEDVVNGFAKIGEEVGNIDGVYHSIAFANIEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKIMPNGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLAYDLGPDNIRVNAISAGPIRTLSAKGVGGCNTILKEIEERAPLRRNVDQEEVGKTAAYLLSDFSSGVTGENIHVDSGFHAIK
>NZ_CP042286.1|WP_146501812.1|2319777_2321490_-|IS1182-family-transposase
MYKNYNMTQLTLPMETSVLIPTNDISRHVNDIVETIHDNEFDEFRHHRGATSYHPKMMLKVILYAYTQSVFSGRKIEKMLNDSIRMMWLSQNQKPSYKTINRFRVNPKVDALLESLFIQFYSQCVKQNLIDDKAIFIDGTKIEANANRYTFVWKKSIQNHESKMNEDSKALYHELVTNKIIPEIKKDHDNELTKEEIDLIGSHLDKEIEDLNQHINNEKCTKTRKQIRLKRTKIKKYKKQINDYFERKYRYEFQKSILKDRNSYSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLSYNVYQNPTDTRTMIPFLNSIQETYGHLPEYIVADAGYGSESNYKAIIDDFNRTPLITYGMFIKDKTKKYKSDIFNTQNWNYDEINDEFICPNNKRLGFKRYAYRHDKYGYKRDFKLYECDDCSECPLKNQCMNFNSKTNKKIMKNYNWEYFKSQINKKLSEPETKNIYSQRKIDVEPVFGFMKAILGFTRMSVRGLNKVKRELGFVLMALNIRKVVAQRAENNQKIYKKDNFYIISIEIVFFSLIQELYVPDSLNFILVDCLLVYLK
>NZ_CP042286.1|WP_047557488.1|2318723_2319815_+|hypothetical-protein
MFTYFKSALKNAKPQLLLTLIYSFIAFAVIAVVYLLANFQLAKSVQTISIYSQFGQQPPGDAYLFVIAILLIAAALSLFVFTQIFIGIINVMKRAMNNEKVQFTNLFIAFKKGNYLKSVIIGLVSIAMLIVLSLLTSLLYKLLSPVLEMIMNSVQSSAADSTHMIGIAITTQSIIIIVVSLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFIKFFIGILLLNLITILFKVPVGYLITLNTQSLSQNVAENIIKVYTVLTIILFVVIHAIILMGIVQYYLKRGQKITKHKVKSADKNKNVVTEPKSTKVENEKVTTSVETKTEKAQDSLKDETTKTITSDKPEDNQPK
>NZ_CP042286.1|WP_000019747.1|2317483_2318464_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESTICSGTHSHSHNHHAHHHAHVH
>NZ_CP042286.1|WP_000003754.1|2317161_2317482_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEIHTDTLERVTDIFKALGDYNRIRIMDLLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAINHANHPKESGL
>NZ_CP042286.1|WP_031787719.1|2316345_2317011_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVAFTAGVRQSDQLNALKSQGMKATLVDVENDSIETLTETFKPFDKVIFSVGSGGSTGADKTIIVDLDGAVKSMIASKEAGVKHYVMVSTYDSRRQAFDASGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHYNNQEFQIISGDQDIKEALTSFQHDID
>NZ_CP042286.1|WP_001127968.1|2314952_2315891_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSTFGYHLDNDKTGECWCVSAHPNGTSEIINGPYKGQTLDQVWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEIAHHVQQGTVESILRYIKVKPGEFYFIPAGTVHTITSGILAYETMQSSDITYRLYDYNREDDLNNERPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLQGEGQIIVDGEIFKLTTGTNFILTSEDLDSVFEGEFTLMISYV
>NZ_CP042286.1|WP_000808819.1|2314691_2314922_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTVPRIVAILGIISAVITFKDKQISTSLKFSAVLINMLPLFGTFVATN
>NZ_CP042286.1|WP_031787716.1|2312848_2314222_-|EVE-domain-containing-protein
MTAEANYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGHQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAILEVSENNGLKSPFEMVQKPDLLEDEKEETLKPFIMLVVDQKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDPDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEDIKAKYSEQFLKYTRIVKVKHD
>NZ_CP042286.1|WP_001123296.1|2311826_2312240_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPKNYQFATLKGEIGQQFFEQHPEAANKNSVILQKGDKIYFESQAIIKLITALPNATKLLGVGLWIVPKPIRNFGYRMFANNRNRMWKTTWHQPNEYEKSFFLDDNAKVKLTD
>NZ_CP042286.1|WP_000220898.1|2323523_2323610_+|hypothetical-protein
MTYGSIIAILCALFVVFFIPYMEKKNKK
>NZ_CP042286.1|WP_047557492.1|2323739_2324597_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNKATTYTKDVIKQLREKGFKVFLATGRSHSEIHQLVPQDFIVDGIISSNGTIGEVDGQIIFKHGLSLTQVKQIVNLAKQQHIYYEVFPFEANRVALKEDETWMREMIHSQDPINGVSHSEWSSRQDALAGKIEWVSEFPKGEYSKIYLFSSNLEKITTFRDELKQNHVQLHISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGIRQDETLVIGDSDNDRAMFEFGHHTVAMKNARPEIQALTSDVTTYTNEEDGAAKYLAEHFLAE
>NZ_CP042286.1|WP_047557495.1|2324664_2325447_-|ABC-transporter-ATP-binding-protein
MLITLNQVGRLKQGKTILQDVSWQIAEGDKWVLYGLNGAGKTTLLNILNAYEPATSGTVNLFGKISGKLGYSADDVRQQIGFVSHSLLEKFQEGETVIDVVMSGAFKSIGIYKNVDDDIISEAHQLLRLVEMSDKAQQFIGYLSTGEKQRVMIARALMGQPRILILDEPAAGLDFIARESLLNILDSLSDTYPTLAMIYVTHFIEEITAKFSKILLLKDGQSIQQGAVEEILTSENMSHFFRKKVEVQRWKQRFSMMMFE
>NZ_CP042286.1|WP_031788232.1|2325675_2327481_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNEDSTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKNEYLQGVSFISETDTEVIVQLIEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDAEGNVQDRDSYTAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETKKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP042286.1|WP_072324271.1|2327931_2328147_+|hypothetical-protein
MYNGVVLFCKYFHNKILKILKQYFCFTFSKYLCGHIYDTLFNFVTFILTKLIFVYIEDYVLALYTKDSHIH
>NZ_CP042286.1|WP_031788233.1|2328162_2329713_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQFIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKLLAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKDAKVEENVNTEAKTNADEPSTLEDDPEALLDNYNTEDVDAHNYNNIDHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP042286.1|WP_047557498.1|2329746_2331867_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYNGQYVTIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLILERANKKGIRIAGADSDLHDLKQSIAQHQTIDLSVEEQKVIILYALIQAKDPVKQYSLAQEIGVSVQTLAKMLDDLEIDLNGYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVYHSLNQIQQDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDEIYESVQHTLEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSSNNQCEENKIKSFVKKVESISGMNFVDIDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKYKYPRLFENVRLALNDCWPELIFPESEIAFIVLHFGGSIKNQGNRFLSILVVCSSGMGTSRLLSTRLEQVFNEIERITQASVSDLNTLDLTQFDGIISTVNLDITSPYLTVNPLLPDSDVSYVAQFLNTKSIQHDETVYTVNENKLNPLEKLTYIEDNNREGKAVLLSDDDDQLSNDHSEQLIQNMRSGLTLVDSVKIDYTHVTQWNEYIADYLLHHHVINDAPSFAELLEQRLKDNPGWILDPYPVAIPHLKDKMIQHPIILITCLNQPLILPSIQNDHFTIKYMISMFIPENDFMSSLVSDLSEILSLQLESIDTFMEKPQEFETLLRNKFLKRIQNQFI
>NZ_CP042286.1|WP_001292149.1|2331879_2332314_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP042286.1|WP_000648735.1|2332313_2333420_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALATEHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKQAVLDITGPLGDHIHFANSAVDRIVPLQKNENILDVMVEPFYEWVIEKNAWYGPELEHIKYVDDLTPYIERKLLTVNTGHAYLAYAGQFAGKATVLDAVEDSSIEAGLRRVLSETSQYITNEFDFTEEEQAGYVEKIIDRFNNPYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDSADQETVEKNNYIDAHGLKAFLNEYAKVDDGLADEIIEAYNSLS
>NZ_CP042286.1|WP_146501814.1|2333724_2341068_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTASAAEQNQPAQNQPAQPADANAQPNANAGTPGAQANPAAQPAGTSANQPQPAANQGGQVDPNAQPAANQGGQANPNAQPAGQGNQVDANNAAQAQPGNQVGQGNNQTAPANNAAPANQAQPANAAAPAGQPAAAQPAPVASNTQTQDPNANNTGEGSINTTLTFDDPAIKTDENRQDPTVTVTDHVNGYTLINNGKVGFVNSELRRSDMFDKNSPQNYQAKGNVAALGRVNANDSTDHGDFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLELQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLSTTFPDGNEDSTVLKNMTVNYDQNANKLTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLIYRTASDAVINNAQPEVTLIADPFSVAVEMNKDALKQQVNAQVDDSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDDQAAIAELDAKAQEKITAAQQNTKVTRDEITAFVTKVNNDKNNAIAEINKQTTAQGVTTEKDNGIAVLEQDVITPTTKPQAKQEIIQAVTTRKQQIKKSTASLQDEKDVANNKIGQIETKAIKDIDAATTNEQVEAIKTKAINDINQTAPTTSAKAAALDEYYEVVQAQIDEAPLNPDTTNEEVAEAIERINAAKEAGVKAIEATTTAQDLERVKNEEIFKIENLTDSTETKMNAYKEVKQAAAAKNAQNAAVTNATDEEVAEAKQAVDTAQKEGLHDIKVVKSKQEVADTKAKVLDKINAIQTQVRVKPEATAAVENAYNTRKQEIQNSNASTTEEKEAAYTQLDAKKQEALTNIDTENTNNGVATAKDNGISAINQIQAATTKKTEAKAEIAQKASERKTAIEAMNASTTEEQQAAKDKVDEAVVTANADIDNAAANTDVDNVKTTNEGTIAAITPDANVKPAAKQAIAEKVQAQETAIDANNGATTEEKAAAKQLVQTEKTTADTAIDDAHSNADVEAAKNAEIAKIEAIQPATTTKDDAKQAIATKANERKTAIAQTQDITAEEIVAANTDVDNAVTQANSNIEAANSQNDVDQAKTNGETSIDQVTPTVNKKATARNEITTILNNKLQEIQATADATDEEKQDAETEANTENAKANQAITAANTNAEVDEAKATAEAAINAVTPKVMKKQAAKDEIDQLQAAQTTVINNDQNATNEEKEAAIQQLAQAVTDAKNNITAANDNNGVDAAKDAGKNSIQSTQPATAVKSNAKNDVDQAVATQNQAIDNTTGATTEEKNAAKDLVTKAKEKAYQDILNAQTTNEVTQIKDQAVTDIQGITADTTIKDVGKGELTTKANDQKALIAQSADATTEEKDQANQQVDAQLTQGMQNIENAQSIDDVNTAKDAGIQAIEPIQASTDVKTNARTDLLNEMQNKINDILNDNDTTNEEKEKGIGPVRNAYEEGLNNINAASTTVDVNNAKDLAVNKVQHIQATPVKKTAGKTELEQAATERKQQIEQTPNASQQEINDAKQEVDNELNQAKTNVDQSSTDGYVDAAVKDGKAKINAVKTFSEYKKDSLAKIEDAYNAKVSEADNSNASTASEIAEAKQKLAEFKQTAEQNINQATSKDDIEIQIHNDLDNINNYVIPSAKKESATNELYAYADQKRNNISADTNATQDEKQAAINKVNQTVESALESINDGVENSDVDDALAQGKAAIDAVQVEATVKPKAIQVIDTKAEETKDSINHSDQLTTEEKSEALATIKQITDQAKQGINDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISNQTTNAEIATVKNSALEELKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADNLDKTQTNTEVAELQNVTIPAIEAIVPQNDPNANATPENTGQPNSTAATTNENVDAPSTTPSNSSMSTDESTTAPSANNSSSDNTTTNSNGNVNASTSTDNGTTDKPSPETNSATPTEGTTNNNTTAATSGNDATSNNSSSSTAPTATENTVASSATEGNMEPSTNDTNQNADVNNNADSQPANGKVAQPKSEATHKSEKDGKDSTKQSMVESTNETLPSADITEPKAPSVSSKDKEGSMSEQSEAGQSKSDTKVASNETDETTGKVDTDVSNNSTTSKSVDAKDNMTSKDASQKDNMTTAGATDKATQNDNTKASVASVSNENNSTNQEMTETRKSNIDKDNAMSVQQNKDTKAEPKTKQKAKALPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDRQTEE

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Crispr_ID: NZ_CP042286_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042286_6

2398141-2398258

Orphan

Consensus_repeat	Method
TCATTGGTTTCCCATGATTTTTTAATATT	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP042286_6

>merge|NZ_CP042286|6|2398141-2398258|CRISPRCasFinder
TCATTGGTTTCCCATGATTTTTTAATATTTTTCTTTTGAGTTACTCGAAAATTTCTCTCTTTACTCGAAAGCTCACAAAACCCTTGATGTCATTGGTTTCCCATGATTTTTCAATATT

>NZ_CP042286|6|5|2398141-2398258|CRISPRCasFinder
TCATTGGTTTCCCATGATTTTTTAATATT	TTTCTTTTGAGTTACTCGAAAATTTCTCTCTTTACTCGAAAGCTCACAAAACCCTTGATG
TCATTGGTTTCCCATGATTTTTCAATATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042286.1\|WP_000875478.1\|2386715_2386931_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_047556285.1\|2405183_2405993_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184207
NZ_CP042286.1\|WP_047556289.1\|2402722_2403526_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP042286.1\|WP_000655246.1\|2397026_2397209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042286.1\|WP_000791627.1\|2403530_2404337_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP042286.1\|WP_047557603.1\|2394898_2396563_-\|acetolactate-synthase-AlsS	unknown	unknown	gnl\|CDD\|236312
NZ_CP042286.1\|WP_047557609.1\|2392523_2393153_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153234
NZ_CP042286.1\|WP_141772558.1\|2398777_2399956_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP042286.1\|WP_001250038.1\|2402044_2402482_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP042286.1\|WP_047556287.1\|2404326_2405187_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184205
NZ_CP042286.1\|WP_047557606.1\|2393347_2393773_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_CP042286.1\|WP_000101625.1\|2407887_2408277_-\|30S-ribosomal-protein-S11	unknown	unknown	gnl\|CDD\|180007
NZ_CP042286.1\|WP_000569649.1\|2406869_2407814_-\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NZ_CP042286.1\|WP_047557622.1\|2388077_2388494_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP042286.1\|WP_047557618.1\|2391503_2392433_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP042286.1\|WP_072467314.1\|2387159_2388008_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_CP042286.1\|WP_047556283.1\|2406484_2406853_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
NZ_CP042286.1\|WP_000024499.1\|2394157_2394862_-\|acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
NZ_CP042286.1\|WP_000170975.1\|2401632_2402031_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP042286.1\|WP_047557620.1\|2388899_2391329_+\|polysaccharide-lyase-8-family-protein	unknown	unknown	gnl\|CDD\|238517

Protein	Function_ID	Function_description	E-value
NZ_CP042286.1\|WP_047556285.1\|2405183_2405993_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	1.37737e-178
NZ_CP042286.1\|WP_047556289.1\|2402722_2403526_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.26095e-119
NZ_CP042286.1\|WP_047557620.1\|2388899_2391329_+\|polysaccharide-lyase-8-family-protein	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
NZ_CP042286.1\|WP_047557603.1\|2394898_2396563_-\|acetolactate-synthase-AlsS	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
NZ_CP042286.1\|WP_047557609.1\|2392523_2393153_+\|glutamine-amidotransferase	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	3.97103e-49
NZ_CP042286.1\|WP_141772558.1\|2398777_2399956_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.39529e-21
NZ_CP042286.1\|WP_001250038.1\|2402044_2402482_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	4.91074e-100
NZ_CP042286.1\|WP_047556287.1\|2404326_2405187_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
NZ_CP042286.1\|WP_047557606.1\|2393347_2393773_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	9.0144e-34
NZ_CP042286.1\|WP_000101625.1\|2407887_2408277_-\|30S-ribosomal-protein-S11	gnl\|CDD\|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	2.01588e-89
NZ_CP042286.1\|WP_000569649.1\|2406869_2407814_-\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	1.89947e-175
NZ_CP042286.1\|WP_047557622.1\|2388077_2388494_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.47403e-41
NZ_CP042286.1\|WP_047557618.1\|2391503_2392433_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.61595e-59
NZ_CP042286.1\|WP_072467314.1\|2387159_2388008_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	5.2105e-149
NZ_CP042286.1\|WP_000791627.1\|2403530_2404337_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.57813e-48
NZ_CP042286.1\|WP_047556283.1\|2406484_2406853_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	5.784e-63
NZ_CP042286.1\|WP_000024499.1\|2394157_2394862_-\|acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	2.85186e-119
NZ_CP042286.1\|WP_000170975.1\|2401632_2402031_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82

>NZ_CP042286.1|WP_000655246.1|2397026_2397209_-|hypothetical-protein
MKDSIFWKKAFIPVYFIVAMLVFLLFRFYIKTDNFSMYLMIIFLICLGTASIIYNYKTNR
>NZ_CP042286.1|WP_047557603.1|2394898_2396563_-|acetolactate-synthase-AlsS
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELDTQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEPFINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVSGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>NZ_CP042286.1|WP_000024499.1|2394157_2394862_-|acetolactate-decarboxylase
MANVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFMADTSYETKDKSSEAVFEEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIHDEDFTNANIDYKDIADEIREAE
>NZ_CP042286.1|WP_047557606.1|2393347_2393773_+|MAP-domain-containing-protein
MKLKSFVTATLALGLLSTVGATLPNHEASADSNNGYKELTMDGKHTVPYTISVDGITALHRTYFVFPENKNVLYQEIDSKVKNELASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>NZ_CP042286.1|WP_047557609.1|2392523_2393153_+|glutamine-amidotransferase
MKNVYFYIIDGLADWEISNILAELNSKRFFKKDAQTINIEMVSNSKSPITTMGGININPESLIEEISISKDTFLILPGSDTWNDSKHLPVIKVAKEILSNGGYVGAICGATIPLANIGILNEYYHTSNDLLYLESFSSNYHGQKLYIDKPSVSHKNLITASSTGTLMWTKDILQKLDVFKNSTLDAWFNYFSTGNLKHYFELLQTLNKE
>NZ_CP042286.1|WP_047557618.1|2391503_2392433_-|YafY-family-transcriptional-regulator
MKISRLISIILILNERKRVSAKELSELMEVSKRTIYRDVEAINIAGIPVYSIPGVGGGFEIMENFKLDKNTFTENELVSLLISNSNFPEKLKNKDFYNTKLKINSLIPKEKLNTINTQVAQFHMDSKHWNNLRNIDDQLIKFKNAIQNNQVLKVKYINHLGNITEREVEPYQLILKAGQWYGYVYCNLREDFRLLKLTRVLKMQASGSKFIKKVYKEPSLSTDRDFEKLKMTIKLRVHESIVECLLDFCDYESFRQENKRYYVVDFPFIDNSYYFGLILSFGDKCEIIEPAEIRYKMKQIIKKLANNYL
>NZ_CP042286.1|WP_047557620.1|2388899_2391329_+|polysaccharide-lyase-8-family-protein
MTYRMKKWQKLSTITLLMAGVITLNDGEFRSVDKHHIAMADTNAETPDYEKLKKTWLDVNYGYDQYDESNQDMKNKFEATEKEATNLLSSMKTDNNRTYLWDSAKDIDNKSADMTKTYRNIEKIAEAMKNPKTTLNTDQNKNKVKVAMKWLHENAYGKDPDKKVKELSENFTKTTGKNTNLNWWDYEIGTPRALTNTLILLKEDFTDKEKKKYTAPIKTFAPNSDKILSSVGQPEQAKGGNLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYVQSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETPFNDKTQNNTTLKSWIDEGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDAMDESTKAKYKQIVKTSVESDSSYKQTDYLNSYSDIDKMKSLMTDSTISTNDLTQQLKIYNDMDRVTYRNKELDFAFGLSMTSKNVARYESINGENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLSGTTTLDNEEPKENKNSDKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPMTTIENRKANGYTMYNDDRQTITSNINDQETNSVFLESTDNKKNIGYHFLNKPKITVKKVSQTGKWSEINKSQKSDDKKDEYYEVTQKHSNTDDKYGYVLYPGLSKDVFKSKANQVTVVKQDDDFHVVKDNDSVWAGVNYSDSTQTFDINGTKVEVKAKGMFILKKKDDNTYECSFYNPESTNSATASDIESKISMTGYSITNKNTSTSNESGVHFELTK
>NZ_CP042286.1|WP_047557622.1|2388077_2388494_-|MerR-family-transcriptional-regulator
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDKNGYRIYTDSDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNHDANVERLWERK
>NZ_CP042286.1|WP_072467314.1|2387159_2388008_-|aldo/keto-reductase
MNHIEISKDVKIPVLGFGVFQIPQEQTADAVKEAIKAGYRHIDTAQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEGTIKSIERSLQRLNLDYIDLVLIHQPYNDVYGSWRALEELKENGKIKAIGVSNFGVDRIVDLGIHSQIQPQVNQIEINPFHQQEEQVAALQKENVVVEAWAPFAEGKNQLFQNQLLQGIADKYNKSIAQVILRWLVERDIVVLAKSVNPARMAQNLDIFDFDLTEEDKQQIATLEESNSQFFSHADPEMVKALSSRKLNV
>NZ_CP042286.1|WP_000875478.1|2386715_2386931_-|hypothetical-protein
MKYKHFAIITLVTGIIMLTTMYFLPFEYRKMPIFVGMAIIFTVYFSNKKSIDETNIFSMKNRKKSKQENLK
>NZ_CP042286.1|WP_141772558.1|2398777_2399956_-|IS110-family-transposase
MSKRSSVVAHYHNDQFQREFTIQNNKNGYNYLLKYLNNLDHLQIIFESTGIYSRGMTRFCRVNQINYIEMNPLEAKFRTSSLRSWKTDQADAHKLAQLAPTLKATEAISMYGDIFFELRERARFHLEIENEQNRLKFEIVEQLHQTFPGLEKLFSSRYSIIALNIAERFTHPDMVRNMDIDTLISYIFNSTDKGLSMNKAENHAHQLVNIARESYPNVDRHSFLVEKARLLIRQLKQSIQHLKQLDEDMIQLAQQLDCFENIHSIPGIGKLSAAMIIGELGNITRFKSNKQLNAFVGIDIKRYQSGSTQSRDTINKRGNKKARRLLFWVVMNIIRGQHHYDNHVVDYYYKLRKQPHEKAHKTAVIACINRLLKTIHYLVMNQKLYDYQMSPH
>NZ_CP042286.1|WP_000170975.1|2401632_2402031_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>NZ_CP042286.1|WP_001250038.1|2402044_2402482_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>NZ_CP042286.1|WP_047556289.1|2402722_2403526_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTDLNIPVEQWQYAMNRTLPDDIYVKNVDTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEISDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
>NZ_CP042286.1|WP_000791627.1|2403530_2404337_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWVFVLILLFMKLAKIQFWFLIRGLTPIFFFLIFTLLMHIFLTKGGHVLFEWHGITIETNGILEGIYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVQRTSYRQLKWQLRDTLSLIMIIPIAIILFVLKYSGV
>NZ_CP042286.1|WP_047556287.1|2404326_2405187_-|energy-coupling-factor-transporter-ATPase
MSIRFDDVCYTYQQGTPYQHQAIHDINTEFEQGKYYAIVGQTGSGKSTLIQNINALIKPTSGTVTIDGVTVTHKTKDKFIRPLRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMDLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMSLLKSLQTDENKTIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLLNWHIGLPDIVQLQYDFEHKYQTKLKDIALTEEAFVSLYKEWQHEK
>NZ_CP042286.1|WP_047556285.1|2405183_2405993_-|energy-coupling-factor-transporter-ATPase
MEDMNSIITFKKVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNSQVVTDDNLEKLRKEIGIVFQNPENQFVGSIVKYDVAFGLENHAVPHDEMHRRVNEALKQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPNARHNLLNIVRKVKEEHDITIISITHDLTEAMEADHVIVMNKGNVYKEGTATDIFDQAESLTKIGLDLPFPIKMSQLLGHHTSFLTYEGLVNRL
>NZ_CP042286.1|WP_047556283.1|2406484_2406853_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTAVQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
>NZ_CP042286.1|WP_000569649.1|2406869_2407814_-|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
>NZ_CP042286.1|WP_000101625.1|2407887_2408277_-|30S-ribosomal-protein-S11
MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP042286_3	3.2\|849805\|34\|NZ_CP042286\|CRT	849805-849838	34	NZ_CP042286.1	849613-849646	0	1.0
NZ_CP042286_2	2.1\|200946\|28\|NZ_CP042286\|CRISPRCasFinder	200946-200973	28	NZ_CP042286.1	1565316-1565343	2	0.929

1. spacer 3.2|849805|34|NZ_CP042286|CRT matches to position: 849613-849646, mismatch: 0, identity: 1.0

tcaagagtgtagaggaacgcagttggaagctaag	CRISPR spacer
tcaagagtgtagaggaacgcagttggaagctaag	Protospacer
**********************************

2. spacer 2.1|200946|28|NZ_CP042286|CRISPRCasFinder matches to position: 1565316-1565343, mismatch: 2, identity: 0.929

ctgtagaaattgggatccaatttctctg	CRISPR spacer
ctgttgaaattgggttccaatttctctg	Protospacer
**** ********* *************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

947689 : 955498

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047557011.1\|947689_948745_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.2e-15	30.4
WP_000149346.1\|948744_949431_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037800.1\|949405_949879_-	DoxX family membrane protein	NA	NA	NA	NA
WP_001093556.1\|950229_950670_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637681.1\|950925_951510_-	hypothetical protein	NA	NA	NA	NA
WP_031787652.1\|951608_952322_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	2.9e-52	43.9
WP_047557009.1\|952325_952745_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	25.2
WP_047557006.1\|952746_953415_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	3.7e-65	57.5
WP_047557004.1\|953769_954363_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.2e-36	38.7
WP_146501717.1\|954346_955498_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	7.8e-23	38.9

DBSCAN-SWA_2

967460 : 981845

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047556989.1\|967460_968519_+	histidinol-phosphate transaminase	A0A1X7QHI1	Faustovirus	1.4e-21	27.4
WP_031787663.1\|968863_969406_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_047556987.1\|969787_970702_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.3e-08	23.4
WP_000193759.1\|971245_972751_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	3.4e-58	32.0
WP_000046961.1\|973088_973589_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.0e-51	71.5
WP_001068500.1\|973608_974478_-	DMT family transporter	NA	NA	NA	NA
WP_000692520.1\|975284_975683_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.1e-53	73.5
WP_047556985.1\|975645_977751_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.4
WP_000562498.1\|977867_978839_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_146501719.1\|979172_980144_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	1.7e-140	79.9
WP_047430122.1\|980130_981087_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	6.5e-07	60.0
WP_000616904.1\|981083_981845_+	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	2.7e-16	30.1

DBSCAN-SWA_3

1033217 : 1046721

Staphylococcus_phage(80.0%)

integrase,coat,terminase

attL 1027897:1027915|attR 1041297:1041315

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1027897:1027915	attL	NA	NA	NA	NA
WP_001050022.1\|1033217_1035590_+	ribonuclease R	Q0GXV6	Lactococcus_phage	2.7e-94	38.9
WP_001085185.1\|1035611_1036076_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
WP_000121223.1\|1036638_1037745_-\|integrase	site-specific integrase	H0UST3	Bacillus_phage	5.9e-76	44.2
WP_072474260.1\|1037750_1038398_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001060953.1\|1038555_1038762_+	hypothetical protein	NA	NA	NA	NA
WP_000164237.1\|1038797_1039025_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000784892.1\|1039021_1039195_+	hypothetical protein	NA	NA	NA	NA
WP_001231376.1\|1039161_1039365_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
WP_000403833.1\|1039366_1039750_+	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	3.3e-63	96.9
WP_001103972.1\|1039750_1040074_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	2.6e-40	93.3
WP_000344760.1\|1040118_1041735_+	hypothetical protein	A0A1W6JPF4	Staphylococcus_phage	1.8e-246	78.1
1041297:1041315	attR	NA	NA	NA	NA
WP_000148368.1\|1041910_1042714_+	DNA primase	Q4ZE69	Staphylococcus_phage	3.1e-151	97.0
WP_001149387.1\|1042700_1042973_+	hypothetical protein	Q4ZE68	Staphylococcus_phage	3.2e-44	100.0
WP_001019773.1\|1042974_1043616_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	2.1e-110	92.5
WP_001190606.1\|1044065_1044407_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	4.2e-57	98.2
WP_000846280.1\|1044418_1044997_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
WP_000448770.1\|1045014_1045233_+	hypothetical protein	NA	NA	NA	NA
WP_000771366.1\|1045283_1045811_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	1.6e-87	96.0
WP_045181470.1\|1045942_1046155_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-31	98.6
WP_001293074.1\|1046151_1046721_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	3.5e-101	98.4

DBSCAN-SWA_4

1176059 : 1230571

Streptococcus_phage(33.33%)

bacteriocin,protease,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047556870.1\|1176059_1177049_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|1177342_1177738_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217738.1\|1178108_1178828_+	adaptor protein MecA	NA	NA	NA	NA
WP_146501747.1\|1178963_1179950_+	competence protein CoiA	NA	NA	NA	NA
WP_047429890.1\|1179997_1181806_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	3.2e-47	25.0
WP_031787339.1\|1182376_1183183_-	DsbA family protein	NA	NA	NA	NA
WP_031787340.1\|1183205_1183571_-	globin	NA	NA	NA	NA
WP_047556868.1\|1183692_1184286_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242105.1\|1184469_1184817_+	hypothetical protein	NA	NA	NA	NA
WP_001077681.1\|1184833_1185469_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270835.1\|1185485_1186295_+	NAD kinase	NA	NA	NA	NA
WP_047556866.1\|1186291_1187146_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_031787343.1\|1187166_1188552_+	magnesium transporter	NA	NA	NA	NA
WP_000395165.1\|1188561_1190406_+	sodium:proton antiporter	NA	NA	NA	NA
WP_000933190.1\|1190642_1191413_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933106.1\|1191553_1192639_-	AI-2E family transporter	NA	NA	NA	NA
WP_047429878.1\|1193003_1194572_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_047556864.1\|1194718_1195477_+	esterase family protein	NA	NA	NA	NA
WP_047556862.1\|1195683_1196193_+	hypothetical protein	NA	NA	NA	NA
WP_047556861.1\|1196343_1197534_-	MFS transporter	NA	NA	NA	NA
WP_000258637.1\|1197511_1198687_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_047556859.1\|1199120_1200605_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_072467171.1\|1200585_1200852_+	hypothetical protein	NA	NA	NA	NA
WP_047556855.1\|1200851_1202414_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	8.4e-36	28.6
WP_000480656.1\|1202722_1203526_+	TerC family protein	S5MAL1	Bacillus_phage	7.8e-30	39.5
WP_047556853.1\|1203758_1206065_+\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	1.4e-10	26.4
WP_000021861.1\|1206080_1207439_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_047556851.1\|1207577_1209086_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287261.1\|1209578_1210148_-	competence protein ComK	NA	NA	NA	NA
WP_000876831.1\|1210357_1210576_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_047556849.1\|1210656_1211643_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1211837_1212014_+	YkvS family protein	NA	NA	NA	NA
WP_146501749.1\|1212028_1212631_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_100848614.1\|1212929_1213007_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_047556844.1\|1213965_1215930_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000668624.1\|1215932_1216253_+	YxeA family protein	NA	NA	NA	NA
WP_047556842.1\|1216249_1216891_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-20	33.2
WP_047429854.1\|1216978_1217224_-	hypothetical protein	NA	NA	NA	NA
WP_072467168.1\|1217553_1217841_+	hypothetical protein	NA	NA	NA	NA
WP_047556837.1\|1217846_1219328_+	glycosyltransferase	NA	NA	NA	NA
WP_000766007.1\|1219632_1219989_-	DoxX family protein	NA	NA	NA	NA
WP_000039585.1\|1220452_1221412_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001248711.1\|1221460_1221577_-	hypothetical protein	NA	NA	NA	NA
WP_000867361.1\|1221657_1221870_-	NINE protein	A0A060AN66	Enterococcus_phage	1.9e-07	49.1
WP_047556836.1\|1222034_1222586_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_047556834.1\|1222637_1223576_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_072292049.1\|1223726_1223804_+	hypothetical protein	NA	NA	NA	NA
WP_072467193.1\|1223907_1225119_+	isochorismate synthase	NA	NA	NA	NA
WP_047556830.1\|1225105_1226779_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_047526307.1\|1226765_1227569_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000184946.1\|1227561_1228383_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_047556828.1\|1229016_1229346_-\|protease	cysteine protease	NA	NA	NA	NA
WP_047429833.1\|1229383_1230571_-\|protease	cysteine protease	NA	NA	NA	NA

DBSCAN-SWA_5

1250885 : 1259355

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861575.1\|1250885_1251368_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.7e-19	42.0
WP_047556815.1\|1251354_1252479_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174040.1\|1252482_1253187_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	4.7e-47	42.1
WP_000848349.1\|1253186_1253447_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666811.1\|1253448_1254120_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_047556813.1\|1254112_1256302_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.4e-142	40.1
WP_031787725.1\|1256280_1257765_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-43	31.3
WP_047556811.1\|1257757_1258786_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.8e-63	42.6
WP_000238661.1\|1258788_1259355_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.2e-29	40.1

DBSCAN-SWA_6

1517790 : 1523963

Staphylococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047434937.1\|1517790_1517988_+	XRE family transcriptional regulator	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
WP_078377648.1\|1518677_1518902_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	5.0e-19	72.5
WP_047556643.1\|1519196_1519403_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	3.8e-13	56.7
WP_031786969.1\|1520112_1520223_+	hypothetical protein	NA	NA	NA	NA
WP_031786970.1\|1520651_1520837_+	XRE family transcriptional regulator	A0A0F6N3H3	Staphylococcus_phage	5.4e-19	77.0
WP_047556641.1\|1521348_1521765_+	hypothetical protein	NA	NA	NA	NA
WP_141772551.1\|1522167_1522323_+	XRE family transcriptional regulator	M9NSU5	Staphylococcus_phage	1.5e-14	84.3
WP_072467264.1\|1523141_1523963_+	hypothetical protein	Q4ZE35	Staphylococcus_virus	3.5e-49	69.6

DBSCAN-SWA_7

1874606 : 1883651

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364420.1\|1874606_1875125_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000595019.1\|1875146_1877420_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	7.3e-65	29.5
WP_047556450.1\|1877623_1879903_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.0e-30	35.4
WP_001160681.1\|1880178_1880439_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	6.3e-05	35.3
WP_047556449.1\|1880457_1881597_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.8e-86	45.3
WP_001019183.1\|1881619_1882645_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_031787300.1\|1882646_1883651_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	5.8e-06	29.9

DBSCAN-SWA_8

2006898 : 2054456

Staphylococcus_phage(94.59%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072467218.1\|2006898_2013468_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	9.0e-265	82.2
WP_000836460.1\|2013798_2014110_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	6.7e-46	89.3
WP_031787813.1\|2014131_2016546_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	96.6
WP_047430629.1\|2016836_2018018_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	2.2e-214	97.7
WP_031787815.1\|2018125_2019079_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.0e-76	96.6
WP_047556393.1\|2019075_2019639_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	1.4e-86	84.0
WP_000757544.1\|2019747_2020149_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_031787816.1\|2020751_2021579_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_031787818.1\|2021811_2022813_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	1.1e-177	94.6
WP_001008547.1\|2022953_2023415_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.1e-67	97.4
WP_047435126.1\|2023427_2024609_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	9.3e-213	91.9
WP_047556388.1\|2024619_2025252_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.3e-100	89.0
WP_072467234.1\|2025258_2026290_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.2e-177	87.8
WP_047526879.1\|2026779_2028276_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.4e-24	93.8
WP_146501790.1\|2028790_2029108_+	metalloregulator ArsR/SmtB family transcription factor	A0A2H4PQT4	Staphylococcus_phage	5.6e-40	76.9
WP_047556776.1\|2029104_2030397_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	6.6e-196	85.1
WP_001032829.1\|2030957_2031815_-	autolysin	A0A1W6JQU5	Staphylococcus_phage	2.2e-38	41.4
WP_000384170.1\|2032092_2032317_-	hypothetical protein	NA	NA	NA	NA
WP_146501792.1\|2032516_2032987_+	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.1e-60	75.6
WP_047556379.1\|2033006_2033444_+	competence protein ComK	NA	NA	NA	NA
WP_000038426.1\|2033436_2033880_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.2e-42	68.0
WP_047556774.1\|2034168_2034804_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000492907.1\|2034985_2035606_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001096490.1\|2035888_2036602_-	transaldolase	M1PR54	Cyanophage	1.9e-19	35.3
WP_000091424.1\|2036859_2037162_+	hypothetical protein	NA	NA	NA	NA
WP_001199739.1\|2037392_2037758_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	4.2e-47	78.5
WP_000626064.1\|2037754_2038108_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.7e-11	41.0
WP_047556373.1\|2038477_2039311_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.5e-140	87.7
WP_031787829.1\|2039625_2040534_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	8.3e-137	98.0
WP_000933824.1\|2040658_2041852_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-217	99.5
WP_047556370.1\|2042222_2043815_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	2.0e-311	98.9
WP_072467235.1\|2043994_2044753_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	9.7e-131	92.2
WP_000672016.1\|2044757_2045231_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	9.2e-79	91.7
WP_000718109.1\|2045296_2045554_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.0e-44	97.6
WP_047556368.1\|2045550_2046552_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	7.7e-160	83.8
WP_047556363.1\|2046556_2048035_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	7.4e-260	89.6
WP_072292067.1\|2048197_2048650_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	1.0e-55	69.7
WP_047556361.1\|2048987_2049578_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	1.9e-12	80.0
WP_072467221.1\|2049660_2050656_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.4e-68	99.3
WP_047556358.1\|2050731_2051358_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.5e-63	84.3
WP_047556357.1\|2051398_2051740_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	1.4e-52	92.0
WP_047556356.1\|2051840_2052413_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	9.2e-25	93.1
WP_047556355.1\|2052609_2053167_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.0e-77	94.9
WP_031787841.1\|2053351_2053798_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_047556353.1\|2054219_2054456_-\|transposase	IS3 family transposase	A0A0C5AJ30	Paenibacillus_phage	1.0e-17	62.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042286

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection