CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042388	Leuconostoc lactis strain CBA3625 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP042387	Leuconostoc lactis strain CBA3625 chromosome, complete genome	1 crisprs	DEDDh,csa3,cas9,cas2,csn2,cas3	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042387_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042387_1

830509-830678

TypeII

Consensus_repeat	Method
CGCGCTTCAGATGTCTGTCATTTTAATGAGTTCGAGTACAA	PILER-CR

2 spacers

csn2,cas2,cas9

The CRISPR arrays of NZ_CP042387_1

>merge|NZ_CP042387|1|830509-830678|PILER-CR
GCTTCAGATGTCTGTCATTTTAATGAGTTCGAGTACAATCACGACAAATTTCACACGCTCCAGCGCGCTTCAGATGTCTGTCATTTTAATGAGTTCGAGTACTAGCCCCGACACCAACAAGCATCAGCCCGGGCTTCAGATGTCTGTCATTTTAATGAGTTCAAATACAA

>NZ_CP042387|1|1|830509-830678|PILER-CR
GCTTCAGATGTCTGTCATTTTAATGAGTTCGAGTACAATCA	CGACAAATTTCACACGCTCCAGCGC
GCTTCAGATGTCTGTCATTTTAATGAGTTCGAGTACTAGCC	CCGACACCAACAAGCATCAGCCCGG
GCTTCAGATGTCTGTCATTTTAATGAGTTCAAATACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042387.1\|WP_147000948.1\|829789_830470_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP042387.1\|WP_010006151.1\|837646_838087_+\|ribonucleotide-reductase-protein-NrdI	unknown	unknown	gnl\|CDD\|179443
NZ_CP042387.1\|WP_029508861.1\|835110_835341_+\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|131249
NZ_CP042387.1\|WP_147000942.1\|819691_820513_+\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275313
NZ_CP042387.1\|WP_048702168.1\|821338_822139_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP042387.1\|WP_147001484.1\|829487_829793_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP042387.1\|WP_147000946.1\|824281_825361_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NZ_CP042387.1\|WP_147000943.1\|820488_821346_+\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275314
NZ_CP042387.1\|WP_029509470.1\|840252_840966_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184516
NZ_CP042387.1\|WP_009999817.1\|823617_824013_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP042387.1\|WP_147000947.1\|825273_828417_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|273840
NZ_CP042387.1\|WP_147000944.1\|822175_822961_+\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP042387.1\|WP_147000945.1\|823155_823599_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP042387.1\|WP_147000953.1\|839101_839770_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_CP042387.1\|WP_147000949.1\|830983_832282_-\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
NZ_CP042387.1\|WP_029509465.1\|833278_834673_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP042387.1\|WP_147000951.1\|835444_837616_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|180921
NZ_CP042387.1\|WP_147000950.1\|832481_833147_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NZ_CP042387.1\|WP_147000952.1\|838089_839067_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_CP042387.1\|WP_019040658.1\|830703_830898_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042387.1\|WP_147000948.1\|829789_830470_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.01023e-30
NZ_CP042387.1\|WP_010006151.1\|837646_838087_+\|ribonucleotide-reductase-protein-NrdI	gnl\|CDD\|179443	PRK02551, PRK02551, flavoprotein NrdI; Provisional.	2.76891e-51
NZ_CP042387.1\|WP_029508861.1\|835110_835341_+\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|131249	TIGR02194, Glutaredoxin-like_protein_NrdH, Glutaredoxin-like protein NrdH. NrdH-redoxin is a representative of a class of small redox proteins that contain a conserved CXXC motif and are characterized by a glutaredoxin-like amino acid sequence and thioredoxin-like activity profile. Unlike other the glutaredoxins to which it is most closely related, NrdH aparrently does not interact with glutathione/glutathione reductase, but rather with thioredoxin reductase to catalyze the reduction of ribonucleotide reductase.	4.84874e-31
NZ_CP042387.1\|WP_147000942.1\|819691_820513_+\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	6.40953e-146
NZ_CP042387.1\|WP_048702168.1\|821338_822139_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.46795e-43
NZ_CP042387.1\|WP_147001484.1\|829487_829793_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	3.2172e-27
NZ_CP042387.1\|WP_147000946.1\|824281_825361_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	1.50263e-31
NZ_CP042387.1\|WP_147000943.1\|820488_821346_+\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275314	TIGR04521, ECF_ATPase_2, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	1.99253e-136
NZ_CP042387.1\|WP_029509470.1\|840252_840966_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184516	PRK14115, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	4.83499e-137
NZ_CP042387.1\|WP_009999817.1\|823617_824013_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.77039e-80
NZ_CP042387.1\|WP_147000947.1\|825273_828417_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|273840	TIGR01865, conserved_hypothetical_protein, CRISPR subtype II/NMENI RNA-guided endonuclease Cas9/Csn1. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein found only in CRISPR-containing species, near other CRISPR-associated proteins (cas), as part of the NMENI subtype of CRISPR/Cas locus. The species range so far for this protein is animal pathogens and commensals only.	1.62437e-103
NZ_CP042387.1\|WP_147000944.1\|822175_822961_+\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.64007e-122
NZ_CP042387.1\|WP_147000945.1\|823155_823599_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.34491e-92
NZ_CP042387.1\|WP_147000949.1\|830983_832282_-\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	3.61058e-155
NZ_CP042387.1\|WP_029509465.1\|833278_834673_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	4.33222e-96
NZ_CP042387.1\|WP_147000951.1\|835444_837616_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|180921	PRK07306, PRK07306, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_CP042387.1\|WP_147000950.1\|832481_833147_-\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	4.71081e-42
NZ_CP042387.1\|WP_147000952.1\|838089_839067_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_CP042387.1\|WP_147000953.1\|839101_839770_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	2.5034e-29

>NZ_CP042387.1|WP_147000948.1|829789_830470_+|type-II-A-CRISPR-associated-protein-Csn2
MKQLTLYPHDPWPLNIGVTQLIFANVEPIWQLVQFFQTGEGAILSDDGAILKYKDVVYVGDLATPFDVGLLYIKPLRQLLTQHLDDLHLRELYETDRTIRSIVQRVLFENDLPGEIDTEWNISELLKYLKLRVELPETHGFYGIIEEIIDLSQRLSDDRLLVFVNASVYLRDEQIQALAYDAMLKQVSCLFIDRQNTVNFIGGKGLKQIFIDHDFVQFVSDDTKNE
>NZ_CP042387.1|WP_147001484.1|829487_829793_+|CRISPR-associated-endonuclease-Cas2
MRLMVMFDLPVITSEDRRNYRQFRKLLINEGFLMIQESVYVRVAVNKQSADFLEQRLAKNAPPAGIVQTIIITEKQYTAMKFLTGSLKDDVRNTDDRLVVI
>NZ_CP042387.1|WP_147000947.1|825273_828417_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MVKKHRINKDKHFDENYQNWLAEKDVDNVTKYFKKIIEATDASDKEQYLQLIEEGEFLPTQRNKSNGNIPHQIHGNELTQIIENQSKYYPFLLDTFKKDDKDANKIVALLKFRVPYYVGPLATAESTGNNQNHWLVKRAGQENTIISPWNLDQVVDKDKSGEQFIKRMTGTDTYLLGEPALAVNTPTYQTYNVLQELNNVRVDGQRLDVKTKQKMFNALFKKTKTVSAKAAQDWLAGEYGKSVLLTGLADPKKFNSALTSYHDLKKVFGEQIELLWTNQIELLDNIVEVQTVFEDGAVALRRLQKLLPTELQPFAPALSEKHYTGWGRLSAKLLRTKVVDNLRSLPGTTTFTDGQTVASILDVLWHSSVNLMELVGNVNDTYGVVAWINEQNIDDDNQKDIYALIEDLAGPKDIKRGITQAFKILDDLKRAFGQEPENVYLEFARESQPTSLSNSRLNRVQELYKSLTKTDKLIDLEKAISAETKEKLQDDRLYLYYIQQGKDMYTGDALDIENLSQYDIDHIVPQAMVKDNSLDNRVLVSSRANRLKNDSEVLPADIRTKMTPFWQRLHAQGFISKRKLDNLTRRSISDVQKERFIARSLVETRQIIKNVATLIDNHFEQTKAVAVRSSLTSDMRQYVKVAKNRDINDYHHAHDALLVATVGQYIQNKGFFVKGQLSDNLGNEYNRYTKRKLQDARESAGQSDRINPFSMVVGSMAAATERKAGLMPSVNMATGEIVWTPDNKQYLLKVLDYSKLLVTKRTKVQSGQLYDETLYPSKKNDPKSKAKIPLNHRKNPKLVYGDTEGQLEYHDTNAIDLYGGFNSAKPAYTALVAIGKPGNYKYKLVNVLRQWVNEARQSDDFLMDKIRQTYPDAQLILNKVLYGQVATNKGQLVTVSSATELHNFNQLYLNQSDYNQTTKLLKLKANLADDVDHQNMNDMIRKIVELASKRFTLYATLFKQMSDNFDDNFDTLDFEDKQQLLQRLLTALHANPSTADFKKMKVSNKGRQFYPSGVAFGENDIFIFQSPTGLFERRLTIKELAQRAGIE
>NZ_CP042387.1|WP_147000946.1|824281_825361_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKYSVGLDIGNSSVGWAVINPKTYQILRAKGKNAIGVRLFDSAQTAEERRGYRTTRRRLSRRRWRLRLLNEIFATELAKVDENFLPRLKYSWVNPKDASNPQFNGEDANGAIFGTVALDKTFYQKYPTIYHLRAELINNPAKADLREVYLAIHHIVKYRGHFLNSAEKIDTNQTFDVASLQTALVNYAEHLDDPTEFLSISDENQFAEAIQNQLLRKKERQEKATTFVEGNTKMISQLTGALLGYTVNLEVLFSLTDIDKEDKNKYKVQFDDEELDDKLSEATALSEEQLELIAVLRRAYAGLQLKQILGDKQSISEAMIARYQAHAEQLKWLKNIASIKINILMKIIKIGWPKKMLIM
>NZ_CP042387.1|WP_009999817.1|823617_824013_+|30S-ribosomal-protein-S9
MATAVQYAGTGRRKNSVARVRLVPGNGQITMNGKSIEEYIPFANLREVVLQPFNVTETLGNYDVLVNVVGGGYSGQAGATRHGIARALLTVDPDFREALKAAGLLTRDSRMKERKKPGLKKARKASQFSKR
>NZ_CP042387.1|WP_147000945.1|823155_823599_+|50S-ribosomal-protein-L13
MRTTFLAKPGEIEKKWYIIDAKDVVLGRLSTVVASILRGKNKPTFTPNVDMGDHVIIINAGEVKLTGKKAADKVYYHHSNHPGGLKARTAGNYREFNPEKLLELSIHGMLPKNTLGRKQGLNLHVYAGAEHAHAAQKPEVLDINKLV
>NZ_CP042387.1|WP_147000944.1|822175_822961_+|tRNA-pseudouridine(38-40)-synthase-TruA
MPRYKAVVAYDGSEFFGFQVQTKNGVERQRTVQGELNRAVNQMAKLPTPAIKVVGASRTDTGVHAFGQVVHFDLPFDIQPEGVRKGLNTLLPRDIMIKQVEKVADDFHARFNTHAKRYIYRVSTQDFTDPFKRRYTGHFHWRLDVARIQAALPDLLGEHDFASFAASGNQTATTVRTITRADVEVKSDEQEIVFTFEGNAFLYNQIRIMVGVLLEIGNGRRDVHDIVRLIAVKDREQARFTAPASGLYLDEIYYDAPVVDK
>NZ_CP042387.1|WP_048702168.1|821338_822139_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MNNIMIGRFVPGDSFIHRLDPRTKMIGTFVYILVLLWANSWATYAWAAIFVLGLIRLTGQPFKLYWDGLKPIFWLILFTVILQLIFTPGTPVLYQLGPIKITTPGLINAVYVMLRFILIILMSTILTLTTPPTSIANALEMLLGPLKKLRVPVAELALMLSIALRFVPLLMDETQKIMNAQKSRGMSFSTGGPIKRAKAIIPLLIPLFVGALQRALDLANAMEVRGFKDAVQRTKYRVLHYGHNDMLAFVGLGVFVVIFAIVNLYL
>NZ_CP042387.1|WP_147000943.1|820488_821346_+|energy-coupling-factor-transporter-ATPase
MAITFEKVNFSYGAGTTLAQAILHDVTVTMPTGRVTAIVGQTGSGKSTLVQHINGLLKPTEGRVLVDGFELTPRTKEKQLMQLRKKVGIVFQFPENQLFANTVLADVMYAPLNFGADQATAKAAAEAALRRVGVDESLWEKSPFELSGGQMRRVAMAGTLASDPSVVVLDEPAAGLDPKGQAELLQLVLELKNLGKTVIFISHHMDHVVAVADQVVVMHDGQVVANETPAQLFNRDMAWFKTMKLDLPKAGQFTEKLKAAGVVLPERPLTLPSLATAINAEVGHE
>NZ_CP042387.1|WP_147000942.1|819691_820513_+|energy-coupling-factor-transporter-ATPase
MTQAIEIHNLNYQYDDDQTLFDGFDLTIEAGQWVALVGHNGSGKSTLAKLILGLIEANAGDITVFGVPLSAETVHDIRDQIGMVFQNPDNQFVGATVADDVAFGLENQQLPSADMPKRIDDALTVVGMQGFKDREPHTLSGGQKQRVALASVLALTPKIIILDEATAMLDPDGRETVMATLQDLKARFGDALTLITITHDMDEAALADRVVVINDGQLILDGTPEAVFSQRQVMHDNGLALPFAGELAAQLTPTPEQYLDERELIQWLSRSKK
>NZ_CP042387.1|WP_019040658.1|830703_830898_+|hypothetical-protein
MDKLLTFILIIAAPFIVIGIVYLFGWLLTGLIMLFGVSYASARLVGIALAVLISFGFIGYQGFK
>NZ_CP042387.1|WP_147000949.1|830983_832282_-|GTPase-HflX
MTEQHINAQEPRKVFLVGLTTSQANLTYELEELANLAKANNLVPVETFTQKLERPNPATYFGKGKVEELAEAAKTYEVDMIVANDELSPSQIRNLEKLTNTTVLDRTGLILDIFAQRAQTKEAKLQVQLARLQYQLPRLRTSMSVSLDQQTGAGGGGFTSRGSGETKLEESRRRITSQMVRIRQELAELSKGTSTRSAKRTTNELANVALVGYTNAGKSTLMNRLLARFGIGADTDDTKQVFEKDMLFATLTTTVRQLTLPDKKQFLLSDTVGFVSKLPHNLVSAFKSTLQEAANADLLLQIVDVSDEHYKDMMATTEKTLAEVGVTDVPMITVYNKADRTELVYPDVSGENTITISALDPASQDALIDLIKKQIFNDVQEVTLHIPFDQGAVQAKLAAKHTFSKEDYDETGTLITVELSELERKLYADYIV
>NZ_CP042387.1|WP_147000950.1|832481_833147_-|histidine-phosphatase-family-protein
MSINVYIVRHGETYFNFLHRFQGWSDAPLTPKGIEHGLNAGKRLANIHFDGAYSSDLTRAIHTARYILKNNTAESPEEPTQLFDFREQFFGSFEGINGETVTTTLTAFKDTPFETYTNLITIYGMADAMDTIRQADPYHFAEDDEQWWTRVSRGFNDIRFRHKDGDNVLIVSHGTTIRGIAEKFGRHDFASEPVKNGAVMQLELDPHDAKIVRFNDDTTVF
>NZ_CP042387.1|WP_029509465.1|833278_834673_-|HlyC/CorC-family-transporter
MDSGPSMLLNFVIIVLVLLLAILFTLTEYSLVKVRLSALRDLQENREKPSRNIEHAIYMASHLTEYLSTAQVGITLTSLILGWIGEETVAEIILKTGLIPAEYSGVVSSVSAMIIFTVVHAVFTDLVPKNIAIEEPIKVLMLIVRPVRFFHILLFPLIWTLDHLSNMITHMLGFRTDGEEDIYSQTEILSLSRNAAAAGELDEEDLTFMKRAFEMNDKVAVDIMIDRTSMTAIDVTTTIADAINLYLQDRYSRFPVIADNDKDKVLGYVFIYDLLRQSRINDQDTVAKIMRDIPAVPENMDLHDVMDEMIIKRSPIAIVVDEYGGTSGMITDKDIYEELFGTVRDEIDDVSDDYIEKLGDHRYKVSGKMTLYDFERYFNKKIKELEEDEAVTLTGYVLNHDPEFRAGDTMQVANFKLTALDYDNAYISEFIVQELPTPKQDLNHNGIFDEDEKDDKSNTADSPA
>NZ_CP042387.1|WP_029508861.1|835110_835341_+|glutaredoxin-like-protein-NrdH
MEKVTVYTKYNCVQCKMTKKFLSAQGIPFKEINIEEEVAYVETLKADGFRQTPVVAIEGMPKFSGFRPDVLKKISA
>NZ_CP042387.1|WP_147000951.1|835444_837616_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MPLKEINLDKVTYFDLNNQVNIPKNNQIQLEKDQEALDAFLTENVWPNVLKFDSLSERFEWLFENNFLERAFIEQYRLAFIEELYAYLEGENFNFKSFMAAFKFYNQYALKTNDGQYYVETYIDRVAMNALYYAAGNEALALRLADEMIHQRYQPATPSFLNAGRARRGELVSCFIIQTSDDMNSIGRTINSALQLSKMGGGVGINVSNLREAGAPVMGIANSAGGVVPIMKLLEDSFTFSSQVGARQGAGVVYLSVFHPDIMAFLSTKKENADEKIRVKTLSLGLTVPDKFYELVRKNEDMYLFSPADVEKVYGVPFNYVDITAEYDNMVANDQITKYRLNARTLEEEISKLQQESGYPYIINIDVTNRANPIAGKIVSSNLCSEILQVQTPSELDNGQQYTRLGSDVSCNLGSINIVNMMATPDFETSVDTMVRALTFVSDTSNLDVVPSIAKGNQEKHAIGLGAMGLAAYFAQNQMYYGDEASLDFTSTFFMTLNYYSIKASMKLAKERQEKFFEFDKSAYADGTYFDKYLTQDWAPKTPKVAAAFANHHVPTQRDWLELKENVMTYGMYHAYRHAIAPTGSISYVNDTTATLLPIVNKIEERQEGMIGKVYYPAPGLNNETMPYYVSAYDTDMRKVIDVYAAAQEHIDQGMALTLFMRSTLSTALYEWKKSRTEKMTTRDLTILRHYAFNKGIKSLYYVRTFTDDHQESGVNECESCSI
>NZ_CP042387.1|WP_010006151.1|837646_838087_+|ribonucleotide-reductase-protein-NrdI
MVKINILYASTEGNTVSFVSKLSEVAAAHGDTVVARCIGDETDYANETEPFVAIVPTYLTGGTGTGPEVTEIFTNALGDYIAFGRNQQYLKGVIGSGNRNFNVQFNLTAIRYAERFNVPMLYAYELRGSTFDADKAYHLIKPIFGE
>NZ_CP042387.1|WP_147000952.1|838089_839067_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MVQHLKDNSYTAINWNNIEDELDKATWEKLTQQFWLDTRIPISNDLRHWRGNMTPQEQKTMNLVFGGLTTLDTLQSQDGLAQLKFDALNQKEEAVLNNIQFMESIHAKSYSSIFETLNEKSEIEAIFEWADNNEFLQYKANRINDVYQTGTPLQKKVASVFLETFLFYSGFYTPLYFLGHNKMLNVAEIIKLIIRDESVHGTYIGYKFQIGFNQLSEAEQAELQAWMYDLLYDLYENEENYTHDLYDDLGWYDQVMTFLRYNANKALMNLGQEPMFPDGAEDVNPVVMNGLSTSTANHDFFSGVGNGYLLGAVEAMEEDDYTIGQ
>NZ_CP042387.1|WP_147000953.1|839101_839770_-|phosphatase-PAP2-family-protein
MIVSATNKQRRHALICFLIACLLGLLTKFNIIVPVALDQLLHSLFNTVQSNFGDTVMAIATFLGNPVVDVIYAFILAGVLVIAQLRVPAIWTVVSVLLGDVVLSIIRFIVNRPRPVGHLLSDTASSFPSSHVFGLFVVIFIIGILVTPNINSHRAQIIITWLTQLIGALTIMSRLYFNANFLSDTVAAILFAYAWVIISATLYPKFATFLQRRVPLFEHEEI
>NZ_CP042387.1|WP_029509470.1|840252_840966_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MAKLVLIRHGQSEWNALNLFNGWVDTKLSDKGIAQAKEAGELLAAEGIQFDQAYTSVLTRAITTLHYALEEAGQLYIPEVKSWRLNERHYGALQGQNKAEAAEKWGAEQVHIWRRSYDVLPPLLDSYDEEVTVQGKTYPAFDRRYADVPEGELPLGENLKITLERVLPFWESDIAPQLKAGKNVVIAAHGNSLRALVKHLENISDEDILNVEIANGQPLVYDLADDLSVVSKKTLTK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

37261 : 121826

Leuconostoc_phage(18.75%)

protease,tail,tRNA,terminase,integrase,capsid,portal

attL 78876:78895|attR 116512:116531

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010005501.1\|37261_38977_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_147000570.1\|39042_40296_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_029509217.1\|40299_41094_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_029509216.1\|41097_41877_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.3e-17	39.1
WP_095652505.1\|41987_43793_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	3.5e-86	36.9
WP_147000571.1\|44003_45659_+	adenine deaminase	NA	NA	NA	NA
WP_029509213.1\|45661_46153_+	hypothetical protein	NA	NA	NA	NA
WP_147000572.1\|46180_48583_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	1.4e-82	47.1
WP_010000283.1\|48851_49364_-\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_147000573.1\|49360_50509_-	AI-2E family transporter	NA	NA	NA	NA
WP_147000574.1\|50715_51669_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_147001470.1\|51661_52690_+	phosphomevalonate kinase	NA	NA	NA	NA
WP_147000575.1\|52682_53738_+	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_010000290.1\|53759_54323_-	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	2.2e-15	34.7
WP_147000576.1\|54319_55615_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-19	33.8
WP_147000577.1\|55793_57011_-	MFS transporter	NA	NA	NA	NA
WP_095652496.1\|57137_57941_-	esterase family protein	NA	NA	NA	NA
WP_147000578.1\|58007_59672_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_147000579.1\|59699_60956_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_147000580.1\|61130_61592_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_147000581.1\|61652_63179_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	6.9e-67	46.2
WP_010003146.1\|63175_63766_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	4.7e-24	37.0
WP_147000582.1\|63759_64797_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F205	Synechococcus_phage	1.7e-56	40.9
WP_147000583.1\|64793_66416_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.1e-45	31.9
WP_147000584.1\|66397_68620_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.7e-136	39.9
WP_010006384.1\|68689_69358_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_010006383.1\|69354_69621_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_147000585.1\|69632_70376_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_147000586.1\|70362_71478_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_029509187.1\|71474_71960_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.8e-21	43.7
WP_077282465.1\|72245_73721_-	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_010000313.1\|74296_74686_-	cell division regulator GpsB	NA	NA	NA	NA
WP_147000587.1\|74762_75335_-	DUF1273 family protein	NA	NA	NA	NA
WP_147000588.1\|75382_77575_-	penicillin-binding protein	NA	NA	NA	NA
WP_029509181.1\|77599_78214_-	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	3.0e-21	35.1
78876:78895	attL	NA	NA	NA	NA
WP_147000589.1\|79028_79280_-	hypothetical protein	NA	NA	NA	NA
WP_147000590.1\|79260_79647_-	hypothetical protein	E3W8I0	Leuconostoc_phage	5.8e-15	40.2
WP_147000591.1\|79639_80953_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	3.6e-88	39.7
WP_147000592.1\|81096_81909_+	hypothetical protein	NA	NA	NA	NA
WP_147000593.1\|81980_82937_-	N-acetylmuramoyl-L-alanine amidase	M4I776	Leuconostoc_phage	2.5e-27	34.0
WP_147000594.1\|82920_83394_-	hypothetical protein	NA	NA	NA	NA
WP_147001471.1\|83396_83627_-	hypothetical protein	E3W8H4	Leuconostoc_phage	2.8e-17	60.0
WP_147000595.1\|83775_89091_-	hypothetical protein	A0A2H4JEQ6	uncultured_Caudovirales_phage	3.1e-58	32.1
WP_147000596.1\|89087_89816_-	hypothetical protein	B3GW14	Streptococcus_phage	1.8e-33	32.5
WP_147000597.1\|89815_92899_-	tape measure protein	A0A191KBP6	Streptococcus_virus	3.8e-80	72.8
WP_147000598.1\|92891_93461_-	hypothetical protein	A0A286QMS7	Streptococcus_phage	1.1e-30	38.1
WP_147000599.1\|93462_93801_-	hypothetical protein	NA	NA	NA	NA
WP_129873494.1\|93842_94310_-\|tail	phage tail protein	Q938K6	Temperate_phage	1.4e-34	50.3
WP_147000600.1\|94309_94708_-	hypothetical protein	A0A2H4JHL9	uncultured_Caudovirales_phage	3.0e-14	35.4
WP_147000601.1\|94707_95049_-\|capsid	capsid protein	A0A1P8VVL8	Streptococcus_phage	1.9e-25	53.6
WP_147000602.1\|95048_95441_-	hypothetical protein	NA	NA	NA	NA
WP_147000603.1\|95382_95772_-	hypothetical protein	A0A1S5SE16	Streptococcus_phage	3.1e-08	36.2
WP_147000604.1\|95809_96052_-	hypothetical protein	NA	NA	NA	NA
WP_147000605.1\|96063_96894_-\|capsid	N4-gp56 family major capsid protein	A8ASJ6	Listeria_phage	3.0e-93	66.2
WP_147000606.1\|96896_97508_-	hypothetical protein	NA	NA	NA	NA
WP_147000607.1\|97614_98811_-\|capsid	capsid protein	M1IEV1	Streptococcus_phage	6.5e-73	40.9
WP_147000608.1\|98813_100307_-\|portal	phage portal protein	A0A2H4JHM5	uncultured_Caudovirales_phage	1.1e-130	49.6
WP_147000609.1\|100315_101641_-\|terminase	PBSX family phage terminase large subunit	Q5YA76	Bacillus_phage	1.0e-159	61.3
WP_147000610.1\|101624_102206_-\|terminase	terminase small subunit	O03926	Lactobacillus_phage	4.4e-22	38.2
WP_147000611.1\|102279_102783_-	hypothetical protein	NA	NA	NA	NA
WP_147000612.1\|102912_103536_-	hypothetical protein	NA	NA	NA	NA
WP_147000613.1\|103594_103774_-	hypothetical protein	NA	NA	NA	NA
WP_147000614.1\|103849_104494_-	hypothetical protein	D2IYV7	Enterococcus_phage	1.8e-08	29.1
WP_147000615.1\|104810_105335_-	DUF722 domain-containing protein	E3W8E2	Leuconostoc_phage	3.9e-14	36.3
WP_147000616.1\|105365_105692_-	hypothetical protein	NA	NA	NA	NA
WP_147000617.1\|105691_105886_-	hypothetical protein	A0A097BYH8	Leuconostoc_phage	7.7e-24	82.3
WP_147000618.1\|105882_106164_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_147000619.1\|106313_107363_-	DNA (cytosine-5-)-methyltransferase	A0A218MND0	uncultured_virus	6.0e-123	63.6
WP_147001472.1\|107363_107756_-	dTDP-glucose pyrophosphorylase	A0A2D1GPL1	Lactobacillus_phage	1.2e-20	42.6
WP_147000620.1\|107736_108453_-	hypothetical protein	A0A097BYG8	Leuconostoc_phage	1.1e-110	84.1
WP_147000621.1\|108465_108879_-	single-stranded DNA-binding protein	A0A2D1GPB7	Lactobacillus_phage	1.7e-41	60.7
WP_147000622.1\|108871_109489_-	hypothetical protein	D2JGK1	Staphylococcus_phage	5.1e-13	33.5
WP_147000623.1\|109485_110394_-	DUF1351 domain-containing protein	NA	NA	NA	NA
WP_146975069.1\|110478_110736_-	hypothetical protein	NA	NA	NA	NA
WP_147000624.1\|110739_111537_-	DNA replication protein	E9LUM6	Lactobacillus_phage	1.4e-50	48.8
WP_147000625.1\|111537_111738_-	hypothetical protein	NA	NA	NA	NA
WP_147000626.1\|111727_111925_-	helix-turn-helix domain-containing protein	A0A0A7RUJ5	Clostridium_phage	5.1e-07	44.4
WP_147000627.1\|111924_112164_-	hypothetical protein	A0A097BYE5	Leuconostoc_phage	1.4e-14	50.6
WP_147000628.1\|112280_112541_-	hypothetical protein	NA	NA	NA	NA
WP_147000629.1\|112530_113289_-	phage antirepressor Ant	A0A075KJT3	Lactobacillus_phage	5.1e-71	60.8
WP_055308153.1\|113298_113523_-	hypothetical protein	E3W8C0	Leuconostoc_phage	1.2e-28	86.5
WP_147000630.1\|113785_114133_+	helix-turn-helix domain-containing protein	Q7Y4M0	Streptococcus_phage	3.9e-18	46.7
WP_147000631.1\|114136_114571_+	hypothetical protein	A0A097BYJ1	Leuconostoc_phage	7.5e-11	37.1
WP_147000632.1\|114621_115215_+	hypothetical protein	NA	NA	NA	NA
WP_147000633.1\|115383_116457_+\|integrase	tyrosine-type recombinase/integrase	Q5YAA6	Bacillus_phage	7.5e-36	30.2
WP_095652483.1\|116517_118065_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	2.8e-15	29.8
116512:116531	attR	NA	NA	NA	NA
WP_147000634.1\|118107_119088_-	IMP dehydrogenase	NA	NA	NA	NA
WP_077282455.1\|119111_120284_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	3.9e-38	38.0
WP_147000635.1\|120647_121826_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7DMV4	Lactobacillus_phage	1.4e-11	39.6

DBSCAN-SWA_2

602339 : 611537

Leuconostoc_phage(85.71%)

integrase

attL 596616:596630|attR 614156:614170

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
596616:596630	attL	NA	NA	NA	NA
WP_147000855.1\|602339_603461_-\|integrase	tyrosine-type recombinase/integrase	A0A097BYJ7	Leuconostoc_phage	4.7e-206	93.6
WP_095652256.1\|603582_603783_-	hypothetical protein	A0A097BYD9	Leuconostoc_phage	1.2e-24	78.8
WP_095652255.1\|604461_605889_-	hypothetical protein	V5US55	Enterococcus_phage	3.9e-16	22.8
WP_095652254.1\|605875_606697_-	DNA replication protein	I7A9C3	Enterococcus_phage	3.7e-11	26.6
WP_077282016.1\|606699_607017_-	hypothetical protein	A0A097BYF1	Leuconostoc_phage	3.5e-50	98.1
WP_147000856.1\|607013_607226_-	hypothetical protein	A0A097BYJ5	Leuconostoc_phage	6.0e-30	94.3
WP_077282018.1\|607342_607576_-	hypothetical protein	A0A097BYJ6	Leuconostoc_phage	7.5e-26	68.6
WP_077282019.1\|607577_607739_-	serine/threonine protein kinase	A0A097BYK8	Leuconostoc_phage	4.3e-20	94.2
WP_147000857.1\|607839_608103_-	hypothetical protein	A0A097BYE6	Leuconostoc_phage	3.8e-26	76.2
WP_048801799.1\|608368_608740_+	helix-turn-helix domain-containing protein	A0A097BYI9	Leuconostoc_phage	7.0e-50	90.2
WP_147000858.1\|608740_609172_+	ImmA/IrrE family metallo-endopeptidase	A0A097BYJ1	Leuconostoc_phage	2.2e-63	81.8
WP_147000859.1\|609491_610010_+	DNA topology modulation protein	A0A097BYE2	Leuconostoc_phage	1.4e-96	98.8
WP_077282022.1\|610077_610806_+	class I SAM-dependent methyltransferase	A0A097BYE1	Leuconostoc_phage	1.6e-119	89.3
WP_009999924.1\|610877_611537_+	GIY-YIG nuclease family protein	A0A097BYI4	Leuconostoc_phage	4.8e-126	99.5
614156:614170	attR	NA	NA	NA	NA

DBSCAN-SWA_3

870949 : 880150

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_147000963.1\|870949_872728_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	1.9e-52	42.6
WP_010004631.1\|872764_873370_+	recombination protein RecR	NA	NA	NA	NA
WP_029509493.1\|873366_873627_+	YaaL family protein	NA	NA	NA	NA
WP_010004629.1\|873674_874328_+	dTMP kinase	M1PSC7	Streptococcus_phage	3.5e-52	51.4
WP_010004628.1\|874324_874654_+	hypothetical protein	NA	NA	NA	NA
WP_147000964.1\|874653_875574_+	DNA polymerase III subunit delta	M1NSC1	Streptococcus_phage	4.1e-06	23.6
WP_147000965.1\|875575_876451_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.6e-76	55.3
WP_129873528.1\|876492_877224_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_147000966.1\|877269_878262_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.4e-49	35.9
WP_019041830.1\|878691_879336_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	3.0e-48	45.2
WP_147000967.1\|879382_880150_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	2.8e-24	32.4

DBSCAN-SWA_4

1009148 : 1065607

Lactobacillus_phage(35.0%)

protease,tail,tRNA,terminase,integrase,head,capsid,portal

attL 1016149:1016165|attR 1056613:1056629

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029509609.1\|1009148_1009457_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_029509610.1\|1009459_1010932_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_147001021.1\|1010985_1012425_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_029509612.1\|1012562_1013552_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	8.5e-18	28.4
WP_147001022.1\|1013605_1015000_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	5.0e-117	46.7
WP_010004318.1\|1015186_1016803_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.8e-137	47.8
1016149:1016165	attL	NA	NA	NA	NA
WP_147001023.1\|1016877_1018671_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_147001024.1\|1018845_1020165_+	GTPase ObgE	NA	NA	NA	NA
WP_147001025.1\|1020388_1022074_+	acetolactate synthase AlsS	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	5.7e-22	23.9
WP_029509617.1\|1022280_1022781_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_147001026.1\|1022812_1023781_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	2.3e-100	54.7
WP_147001027.1\|1024079_1024562_-	competence protein ComE	A7KUY9	Bacillus_phage	1.1e-34	56.7
WP_147001028.1\|1024635_1025487_+	bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.2e-30	38.1
WP_147001029.1\|1025516_1026455_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_077282235.1\|1026464_1026767_-	hypothetical protein	NA	NA	NA	NA
WP_068851856.1\|1026759_1027305_-	biotin transporter BioY	NA	NA	NA	NA
WP_010000150.1\|1027409_1028036_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010004878.1\|1028218_1029415_+	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-26	36.1
WP_147001030.1\|1029407_1031114_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_147001031.1\|1031145_1031610_-	substrate-binding protein	NA	NA	NA	NA
WP_147001032.1\|1031622_1032849_-	ABC transporter permease	NA	NA	NA	NA
WP_068851868.1\|1032841_1033735_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.9e-23	31.4
WP_147001033.1\|1034323_1035391_-\|integrase	tyrosine-type recombinase/integrase	E3W8I1	Leuconostoc_phage	6.8e-122	62.0
WP_147001034.1\|1035577_1036183_+	hypothetical protein	NA	NA	NA	NA
WP_147001035.1\|1036366_1036786_-	ImmA/IrrE family metallo-endopeptidase	E3W8B8	Leuconostoc_phage	1.0e-41	59.6
WP_147001036.1\|1036782_1037136_-	helix-turn-helix transcriptional regulator	E3W8B9	Leuconostoc_phage	3.2e-28	59.1
WP_147001037.1\|1037390_1037624_+	hypothetical protein	NA	NA	NA	NA
WP_147001038.1\|1037615_1037906_-	hypothetical protein	NA	NA	NA	NA
WP_147001039.1\|1037993_1038221_+	transcriptional regulator	NA	NA	NA	NA
WP_147001040.1\|1038232_1038511_+	hypothetical protein	NA	NA	NA	NA
WP_147001041.1\|1038936_1039656_+	oxidoreductase	A0A1X9H088	Staphylococcus_phage	8.5e-76	63.7
WP_147001042.1\|1039666_1039864_+	hypothetical protein	NA	NA	NA	NA
WP_147001043.1\|1039867_1040047_+	hypothetical protein	A0A097BYA0	Leuconostoc_phage	3.4e-26	98.3
WP_147001044.1\|1040164_1040356_+	hypothetical protein	NA	NA	NA	NA
WP_147001045.1\|1040348_1040537_+	hypothetical protein	NA	NA	NA	NA
WP_147001046.1\|1040660_1040957_-	hypothetical protein	NA	NA	NA	NA
WP_147001047.1\|1041081_1041294_+	helix-turn-helix domain-containing protein	B3GVX6	Streptococcus_phage	2.3e-05	47.5
WP_147001488.1\|1041309_1042089_+	DNA replication protein	D7RWG1	Brochothrix_phage	8.1e-56	76.7
WP_147001048.1\|1042092_1042365_+	hypothetical protein	NA	NA	NA	NA
WP_147001049.1\|1042434_1043349_+	DUF1351 domain-containing protein	NA	NA	NA	NA
WP_147001050.1\|1043345_1043969_+	hypothetical protein	A0A1P8BKZ7	Lactococcus_phage	4.7e-14	40.6
WP_029509777.1\|1043955_1044369_+	single-stranded DNA-binding protein	A0A097BYB0	Leuconostoc_phage	1.9e-56	78.1
WP_147001051.1\|1044381_1045083_+	hypothetical protein	A0A097BYG8	Leuconostoc_phage	1.5e-109	82.8
WP_147001489.1\|1045072_1045483_+	dTDP-glucose pyrophosphorylase	A0A2D1GPL1	Lactobacillus_phage	3.7e-20	45.7
WP_029509780.1\|1045472_1045748_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_147001052.1\|1045744_1046029_+	hypothetical protein	NA	NA	NA	NA
WP_147001053.1\|1046025_1046217_+	hypothetical protein	A0A097BYH8	Leuconostoc_phage	2.6e-24	90.5
WP_147001054.1\|1046218_1046545_+	DUF3850 domain-containing protein	A0A097BYG6	Leuconostoc_phage	7.3e-51	92.6
WP_147001055.1\|1046577_1046970_+	DUF722 domain-containing protein	E3W8E2	Leuconostoc_phage	3.5e-52	78.5
WP_146975101.1\|1047659_1047839_+	hypothetical protein	NA	NA	NA	NA
WP_147001056.1\|1047841_1049047_+	helix-turn-helix domain-containing protein	A0A097BYC5	Leuconostoc_phage	8.8e-102	47.3
WP_147001057.1\|1049215_1049554_+	hypothetical protein	U5U409	Lactobacillus_phage	4.9e-10	46.4
WP_147001058.1\|1049589_1050033_+	HNH endonuclease	E9LUP7	Lactobacillus_phage	1.6e-40	52.3
WP_147001059.1\|1050037_1050364_+	hypothetical protein	NA	NA	NA	NA
WP_147001060.1\|1050549_1051020_+\|terminase	phage terminase small subunit P27 family	E9LUP8	Lactobacillus_phage	8.3e-48	63.5
WP_147001061.1\|1051006_1052890_+\|terminase	terminase large subunit	E9LUP9	Lactobacillus_phage	1.8e-271	71.5
WP_147001062.1\|1052879_1053074_+	DUF1056 family protein	NA	NA	NA	NA
WP_147001063.1\|1053074_1054226_+\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	1.6e-113	54.9
WP_147001064.1\|1054226_1054952_+\|protease	Clp protease ClpP	E9LUQ2	Lactobacillus_phage	8.3e-71	64.9
WP_147001065.1\|1054952_1056167_+\|capsid	phage major capsid protein	E9LUQ3	Lactobacillus_phage	3.5e-146	65.8
WP_147001066.1\|1056478_1056826_+\|head,tail	phage gp6-like head-tail connector protein	E9LUQ4	Lactobacillus_phage	3.6e-24	53.2
1056613:1056629	attR	NA	NA	NA	NA
WP_147001067.1\|1056797_1057136_+\|head	phage head closure protein	A8YQJ4	Lactobacillus_phage	2.1e-05	32.4
WP_147001068.1\|1057132_1057558_+	HK97 gp10 family phage protein	A0A0M7RDL2	Lactobacillus_phage	1.3e-07	37.2
WP_147001069.1\|1057554_1057923_+	DUF806 family protein	A8YQJ6	Lactobacillus_phage	8.3e-11	34.7
WP_147001070.1\|1057922_1058558_+	hypothetical protein	A0A286QPI7	Streptococcus_phage	6.4e-11	29.2
WP_147001071.1\|1058634_1059000_+	hypothetical protein	NA	NA	NA	NA
WP_147001072.1\|1059238_1062157_+	hypothetical protein	Q9AZL5	Lactococcus_phage	7.1e-113	36.6
WP_147001490.1\|1062496_1063636_+	transglycosylase SLT domain-containing protein	Q9AZL4	Lactococcus_phage	1.6e-68	46.9
WP_147001491.1\|1063650_1064478_+\|tail	phage tail family protein	A0A0M7RF73	Lactobacillus_phage	3.6e-38	34.3
WP_147001073.1\|1064527_1065607_+	hypothetical protein	A0A0M7RDS2	Lactobacillus_phage	2.6e-60	39.9

DBSCAN-SWA_5

1147606 : 1160798

Bacillus_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_147001119.1\|1147606_1148875_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.5e-46	31.5
WP_029509628.1\|1148871_1150143_+	insulinase family protein	A0A2K9V7S4	Bandra_megavirus	9.6e-14	30.7
WP_029509629.1\|1150156_1151035_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_055307552.1\|1151044_1151626_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_029509631.1\|1151758_1152904_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.2e-116	65.3
WP_029509632.1\|1153018_1153708_+	response regulator transcription factor	Q56AR1	Bacillus_thuringiensis_phage	8.0e-07	33.0
WP_147001120.1\|1153886_1154795_+	phosphate ABC transporter substrate-binding protein PstS family protein	A0A222YW41	Synechococcus_phage	3.5e-10	28.0
WP_147001121.1\|1154863_1156219_+	histidine kinase	W8CYF6	Bacillus_phage	6.2e-27	34.5
WP_095652881.1\|1156324_1157206_+	phosphate ABC transporter substrate-binding protein PstS family protein	E3SLK5	Synechococcus_phage	3.9e-06	27.3
WP_029509636.1\|1157301_1158225_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_068852049.1\|1158224_1159109_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_010003307.1\|1159191_1160031_+	phosphate ABC transporter ATP-binding protein	F2Y302	Organic_Lake_phycodnavirus	3.8e-11	28.8
WP_029509638.1\|1160027_1160798_+	phosphate ABC transporter ATP-binding protein	A0A1V0SJ29	Klosneuvirus	2.9e-13	26.7

DBSCAN-SWA_6

1483477 : 1581434

Staphylococcus_phage(22.73%)

protease,holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_147001302.1\|1483477_1484512_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.7e-35	31.3
WP_147001303.1\|1484937_1485138_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_147001304.1\|1485141_1485522_-	DUF3796 domain-containing protein	NA	NA	NA	NA
WP_147001305.1\|1486049_1488938_-	hypothetical protein	NA	NA	NA	NA
WP_147001306.1\|1489125_1490007_-	sortase	NA	NA	NA	NA
WP_147001307.1\|1490020_1492150_-	hypothetical protein	NA	NA	NA	NA
WP_068852706.1\|1492167_1492554_-	hypothetical protein	NA	NA	NA	NA
WP_147001498.1\|1492671_1493250_-	hypothetical protein	NA	NA	NA	NA
WP_147001308.1\|1493266_1493836_-	hypothetical protein	NA	NA	NA	NA
WP_147001499.1\|1493835_1494237_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_147001309.1\|1494322_1495567_-	peptidoglycan DD-metalloendopeptidase family protein	A0A140G6T8	Arthrobacter_phage	1.3e-07	35.9
WP_147001310.1\|1495579_1497538_-	type IV secretion system protein VirB4	NA	NA	NA	NA
WP_048702110.1\|1497540_1498197_-	hypothetical protein	NA	NA	NA	NA
WP_141309043.1\|1498203_1498521_-	hypothetical protein	NA	NA	NA	NA
WP_068852732.1\|1498837_1499617_+	ParA family protein	A0A0K2FLP4	Brevibacillus_phage	9.0e-15	38.7
WP_147001500.1\|1499616_1499880_+	hypothetical protein	NA	NA	NA	NA
WP_147001311.1\|1499963_1500479_-	hypothetical protein	NA	NA	NA	NA
WP_147001312.1\|1500514_1502599_-	hypothetical protein	NA	NA	NA	NA
WP_147001313.1\|1502599_1505572_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_147001314.1\|1505555_1507439_-	AAA domain-containing protein	H6X3M6	Enterobacteria_phage	1.7e-67	31.4
WP_147001315.1\|1507428_1507923_-	hypothetical protein	NA	NA	NA	NA
WP_147001316.1\|1507935_1510194_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_147001317.1\|1510183_1510444_-	hypothetical protein	NA	NA	NA	NA
WP_147001318.1\|1510930_1511572_+	hypothetical protein	NA	NA	NA	NA
WP_048702090.1\|1511589_1511820_+	hypothetical protein	NA	NA	NA	NA
WP_147001319.1\|1512312_1512756_+	hypothetical protein	NA	NA	NA	NA
WP_147001320.1\|1513434_1513866_+	hypothetical protein	NA	NA	NA	NA
WP_147001321.1\|1514316_1514544_+	hypothetical protein	NA	NA	NA	NA
WP_080973687.1\|1514707_1514938_+	hypothetical protein	NA	NA	NA	NA
WP_147001322.1\|1514940_1515210_+	hypothetical protein	NA	NA	NA	NA
WP_048702081.1\|1515215_1515476_-	hypothetical protein	NA	NA	NA	NA
WP_147001323.1\|1515462_1515840_-	hypothetical protein	E3W8I0	Leuconostoc_phage	1.8e-16	40.5
WP_147001324.1\|1515832_1517146_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.3e-87	39.3
WP_147001325.1\|1517360_1518149_-	hypothetical protein	NA	NA	NA	NA
WP_147001326.1\|1518156_1518378_-	hypothetical protein	NA	NA	NA	NA
WP_147001501.1\|1518620_1519235_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_147001327.1\|1519827_1521423_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.6e-125	50.6
WP_147001328.1\|1521422_1524494_-	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	8.5e-24	23.1
WP_147001329.1\|1525018_1525936_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	6.6e-41	38.0
WP_055307866.1\|1526193_1526880_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	9.3e-64	52.7
WP_147001330.1\|1527197_1529291_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	8.8e-65	32.0
WP_146977053.1\|1529429_1529582_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_029510500.1\|1529594_1530050_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_147001331.1\|1530360_1531566_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	4.1e-99	48.5
WP_147001332.1\|1531836_1532652_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-32	37.6
WP_147001333.1\|1532685_1532928_-\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	2.1e-07	38.2
WP_029510520.1\|1533326_1534148_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_147001502.1\|1534311_1535307_+	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_147001334.1\|1535433_1536120_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.6e-63	52.7
WP_010492180.1\|1536466_1537678_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_147001334.1\|1537897_1538584_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.6e-63	52.7
WP_147001335.1\|1538607_1539162_+	plasmid pRiA4b ORF-3 family protein	NA	NA	NA	NA
WP_147001336.1\|1539397_1540033_+	DUF4230 domain-containing protein	NA	NA	NA	NA
WP_147001337.1\|1540246_1540768_-	hypothetical protein	NA	NA	NA	NA
WP_029510504.1\|1541012_1542344_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_010008889.1\|1542421_1543393_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.7
WP_004906279.1\|1543393_1544920_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_002816607.1\|1545139_1545823_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
WP_147001338.1\|1545882_1546158_-	hypothetical protein	NA	NA	NA	NA
WP_147001339.1\|1546395_1547541_-	class C sortase	NA	NA	NA	NA
WP_147001340.1\|1547533_1548712_-	class C sortase	NA	NA	NA	NA
WP_147001341.1\|1548848_1550366_-	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_147001342.1\|1550362_1551460_-	hypothetical protein	NA	NA	NA	NA
WP_147001343.1\|1551456_1554177_-	VWA domain-containing protein	NA	NA	NA	NA
WP_147001344.1\|1554669_1555782_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_147001345.1\|1555683_1555950_-	hypothetical protein	NA	NA	NA	NA
WP_147001346.1\|1556378_1556573_-	hypothetical protein	NA	NA	NA	NA
WP_147001503.1\|1556645_1558298_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_147001347.1\|1558695_1558992_-	hypothetical protein	NA	NA	NA	NA
WP_147001348.1\|1559314_1560064_+	abortive phage resistance protein	NA	NA	NA	NA
WP_147001349.1\|1560266_1560539_-	hypothetical protein	NA	NA	NA	NA
WP_147001350.1\|1560538_1561915_-	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	6.0e-38	29.3
WP_147001351.1\|1562798_1563833_-	DUF389 domain-containing protein	NA	NA	NA	NA
WP_147001352.1\|1564752_1565931_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	2.7e-23	28.8
WP_147001353.1\|1566120_1567653_-	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_147001354.1\|1567701_1568109_-	hypothetical protein	NA	NA	NA	NA
WP_029510447.1\|1569435_1569930_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_095652681.1\|1570154_1571582_-	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	3.1e-69	34.7
WP_147001504.1\|1572364_1573561_-	amidohydrolase	NA	NA	NA	NA
WP_147001355.1\|1573665_1574481_-	SDR family NAD(P)-dependent oxidoreductase	A0A0K0KVL6	Prochlorococcus_phage	1.1e-07	26.0
WP_147001356.1\|1574574_1575942_-	MATE family efflux transporter	NA	NA	NA	NA
WP_147001357.1\|1576061_1577390_-	CapA family protein	NA	NA	NA	NA
WP_147001358.1\|1577398_1578259_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_147001359.1\|1578410_1579259_-	methionine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_147001360.1\|1579831_1580509_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_029509426.1\|1580687_1581434_-\|holin	antiholin LrgB	NA	NA	NA	NA

DBSCAN-SWA_7

1656466 : 1664168

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_147001410.1\|1656466_1658344_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	3.8e-35	29.2
WP_147001411.1\|1658330_1658930_-	C26 family cysteine hydrolase domain-containing family	A0A0P0IKJ1	Acinetobacter_phage	6.0e-35	40.8
WP_095652573.1\|1658966_1659656_-	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_095652572.1\|1659658_1660699_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_146977351.1\|1660871_1661351_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.4e-28	45.0
WP_147001412.1\|1661363_1662557_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.0e-86	43.4
WP_147001413.1\|1662549_1663146_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.6e-25	38.8
WP_147001414.1\|1663109_1664168_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-34	31.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage