CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042390	Leuconostoc lactis strain CBA3626 chromosome, complete genome	0 crisprs	cas3,csa3,DEDDh	0	0	9	0
NZ_CP042391	Leuconostoc lactis strain CBA3626 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

391 : 63861

Leuconostoc_phage(61.7%)

capsid,tail,integrase,protease,head,portal,tRNA,terminase

attL 52230:52282|attR 66340:66392

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146974946.1\|391_2083_-\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	1.3e-69	32.5
WP_146977272.1\|2310_2580_-	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_146974948.1\|2725_3919_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	5.6e-40	34.1
WP_029509830.1\|4065_4881_-	SPFH/Band 7/PHB domain protein	S4VT23	Pandoravirus	4.0e-13	28.1
WP_048701982.1\|4897_5272_-	toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_146974951.1\|5353_6841_-	UDP-N-acetylmuramyl-tripeptide synthetase	NA	NA	NA	NA
WP_146974953.1\|6895_8035_-	cation:proton antiporter	NA	NA	NA	NA
WP_029509826.1\|8186_9314_-\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
WP_146974955.1\|9397_10723_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_146974958.1\|11535_12888_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_146974960.1\|12884_13706_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_146974962.1\|13702_14632_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_146974965.1\|14633_15689_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.9e-28	35.6
WP_048701961.1\|15835_16777_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	1.1e-06	24.8
WP_146974967.1\|17177_18311_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_146974969.1\|18369_19410_+	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_146974971.1\|19687_20218_-	DUF1027 domain-containing protein	NA	NA	NA	NA
WP_146974974.1\|20241_21597_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_146974976.1\|21626_22244_-	metallophosphatase	A0A288TXW7	Enterococcus_phage	5.6e-28	35.0
WP_029509813.1\|22296_22743_-	hypothetical protein	NA	NA	NA	NA
WP_146974978.1\|22744_23839_-	M24 family metallopeptidase	A0A0P0I8D7	Acinetobacter_phage	7.9e-17	29.4
WP_010000600.1\|23955_24273_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_010000601.1\|24301_24601_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_029509811.1\|24755_25331_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_146974981.1\|25360_25879_-	molecular chaperone	NA	NA	NA	NA
WP_146974983.1\|26274_26526_-	hypothetical protein	NA	NA	NA	NA
WP_146974985.1\|26506_26893_-	hypothetical protein	E3W8I0	Leuconostoc_phage	4.8e-17	43.3
WP_146974988.1\|26885_28199_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.1e-89	40.3
WP_146974990.1\|28332_28527_-	CsbD family protein	NA	NA	NA	NA
WP_146974992.1\|28657_29626_-	N-acetylmuramoyl-L-alanine amidase	A0A097BY89	Leuconostoc_phage	4.6e-133	72.8
WP_146974994.1\|29637_30060_-	hypothetical protein	A0A097BYC6	Leuconostoc_phage	6.5e-60	91.2
WP_010004951.1\|30111_30378_-	hypothetical protein	A0A097BYC8	Leuconostoc_phage	1.7e-42	100.0
WP_146974997.1\|30379_30616_-	hypothetical protein	A0A097BYE3	Leuconostoc_phage	4.9e-33	93.6
WP_146974999.1\|30618_31014_-	hypothetical protein	NA	NA	NA	NA
WP_146975001.1\|31024_36325_-	hypothetical protein	E3W8G7	Leuconostoc_phage	8.7e-210	62.3
WP_146975003.1\|36309_37035_-	hypothetical protein	E3W8G6	Leuconostoc_phage	5.5e-67	77.8
WP_146975005.1\|37034_40154_-	hypothetical protein	E3W8G4	Leuconostoc_phage	1.8e-215	66.8
WP_146975007.1\|40207_40459_-	hypothetical protein	E3W8G3	Leuconostoc_phage	1.3e-07	75.6
WP_146975009.1\|40416_40779_-	hypothetical protein	E3W8G2	Leuconostoc_phage	3.4e-57	88.3
WP_146975011.1\|40827_41391_-\|tail	phage tail protein	E3W8G1	Leuconostoc_phage	3.0e-84	84.8
WP_146975013.1\|41392_41725_-	hypothetical protein	E3W8G0	Leuconostoc_phage	2.6e-48	87.2
WP_146975015.1\|41721_42078_-	HK97 gp10 family phage protein	A0A0U4II15	Exiguobacterium_phage	4.2e-20	48.2
WP_146975017.1\|42070_42373_-	hypothetical protein	E3W8F7	Leuconostoc_phage	5.4e-32	62.0
WP_146975019.1\|42362_42686_-\|head,tail	phage gp6-like head-tail connector protein	E3W8F6	Leuconostoc_phage	3.6e-34	70.1
WP_146975021.1\|42696_42972_-	hypothetical protein	NA	NA	NA	NA
WP_146975024.1\|42973_44173_-\|capsid	phage major capsid protein	E3W8F5	Leuconostoc_phage	1.8e-163	78.0
WP_146975026.1\|44185_44737_-\|head,protease	HK97 family phage prohead protease	A0A0M7RF71	Lactobacillus_phage	1.5e-32	45.5
WP_146975028.1\|44714_45869_-\|portal	phage portal protein	E3W8F3	Leuconostoc_phage	1.5e-159	97.7
WP_146975030.1\|46017_47772_-\|terminase	terminase large subunit	E3W8F0	Leuconostoc_phage	3.3e-291	81.9
WP_146975033.1\|48031_48514_-\|terminase	phage terminase small subunit P27 family	E3W8E9	Leuconostoc_phage	3.1e-50	62.5
WP_146975035.1\|48688_49081_-	HNH endonuclease	E3W8E8	Leuconostoc_phage	1.4e-53	78.1
WP_146975037.1\|49157_49580_-	hypothetical protein	E3W8E7	Leuconostoc_phage	1.2e-16	63.5
WP_146975040.1\|49701_50433_-	hypothetical protein	NA	NA	NA	NA
WP_146975042.1\|50799_52005_-	helix-turn-helix domain-containing protein	A0A097BYC5	Leuconostoc_phage	4.0e-195	83.0
WP_146975045.1\|52007_52187_-	hypothetical protein	NA	NA	NA	NA
52230:52282	attL	NA	NA	NA	NA
WP_146977274.1\|53064_53250_-	hypothetical protein	NA	NA	NA	NA
WP_146975047.1\|53538_53730_-	hypothetical protein	A0A097BYH8	Leuconostoc_phage	1.2e-26	92.1
WP_146975049.1\|53713_54118_-	hypothetical protein	NA	NA	NA	NA
WP_146975051.1\|54114_54396_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_146975054.1\|54545_55706_-	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	2.3e-123	60.9
WP_146975056.1\|55706_56099_-	dTDP-glucose pyrophosphorylase	A0A0P0IJF8	Lactobacillus_phage	2.5e-21	44.2
WP_146975058.1\|56150_56846_-	hypothetical protein	A0A097BYG8	Leuconostoc_phage	3.2e-128	96.1
WP_146975061.1\|56857_57304_-	single-stranded DNA-binding protein	A0A097BYB0	Leuconostoc_phage	1.4e-60	81.1
WP_146975063.1\|57290_57914_-	hypothetical protein	A0A1P8BKZ7	Lactococcus_phage	1.2e-14	42.7
WP_146975065.1\|57906_58308_-	hypothetical protein	A0A097BYE9	Leuconostoc_phage	2.6e-66	97.0
WP_146975069.1\|58393_58651_-	hypothetical protein	NA	NA	NA	NA
WP_146975071.1\|58654_59443_-	helix-turn-helix domain-containing protein	Q9MCG3	Lactococcus_phage	2.8e-32	41.5
WP_146975074.1\|59443_59659_-	helix-turn-helix domain-containing protein	A0A1S5S8U1	Streptococcus_phage	1.5e-07	47.5
WP_146975076.1\|59794_59956_+	YjzC family protein	A0A0A7RTS6	Clostridium_phage	1.6e-14	71.7
WP_146975079.1\|60264_60474_-	hypothetical protein	A0A1S5S909	Streptococcus_phage	5.0e-05	50.0
WP_146975081.1\|60466_60658_-	hypothetical protein	NA	NA	NA	NA
WP_146975084.1\|60767_60965_-	hypothetical protein	NA	NA	NA	NA
WP_146975086.1\|60977_61202_-	hypothetical protein	E3W8C0	Leuconostoc_phage	1.8e-29	89.2
WP_146975089.1\|61466_61811_+	helix-turn-helix domain-containing protein	E3W8B9	Leuconostoc_phage	7.0e-28	60.8
WP_146975091.1\|61814_62249_+	hypothetical protein	A0A097BYJ1	Leuconostoc_phage	1.8e-09	33.6
WP_146975093.1\|62285_62666_+	hypothetical protein	A0A1P8VVY3	Streptococcus_phage	2.2e-30	53.9
WP_146975096.1\|62787_63861_+\|integrase	tyrosine-type recombinase/integrase	E3W8I1	Leuconostoc_phage	1.2e-142	71.5
66340:66392	attR	NA	NA	NA	NA

DBSCAN-SWA_2

66964 : 77898

Leuconostoc_phage(63.64%)

integrase

attL 67069:67083|attR 80945:80959

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146975106.1\|66964_67357_-	DUF722 domain-containing protein	E3W8E2	Leuconostoc_phage	1.5e-50	75.4
67069:67083	attL	NA	NA	NA	NA
WP_146977276.1\|67763_67955_-	hypothetical protein	A0A097BYH8	Leuconostoc_phage	3.0e-28	93.7
WP_146975108.1\|68120_68600_-	RusA family crossover junction endodeoxyribonuclease	NA	NA	NA	NA
WP_146975110.1\|68816_70220_-	hypothetical protein	A0A060D5T9	Salmonella_phage	1.7e-08	25.0
WP_146975112.1\|70349_71111_-	hypothetical protein	NA	NA	NA	NA
WP_146975114.1\|71112_71664_-	DUF669 domain-containing protein	NA	NA	NA	NA
WP_146975116.1\|71666_72326_-	AAA family ATPase	E9LUU1	Lactobacillus_phage	1.5e-66	60.6
WP_146975119.1\|72334_72628_-	hypothetical protein	A0A097BYE9	Leuconostoc_phage	7.8e-20	50.5
WP_146977278.1\|72733_72940_-	hypothetical protein	A0A097BYA3	Leuconostoc_phage	2.0e-22	87.3
WP_146975121.1\|73083_73275_-	hypothetical protein	NA	NA	NA	NA
WP_146975123.1\|73384_73582_-	hypothetical protein	E3W8C1	Leuconostoc_phage	5.1e-07	44.6
WP_146975125.1\|73676_73865_+	hypothetical protein	NA	NA	NA	NA
WP_010001150.1\|73976_74192_-	hypothetical protein	NA	NA	NA	NA
WP_146975127.1\|74446_74782_+	helix-turn-helix transcriptional regulator	E3W8B9	Leuconostoc_phage	5.4e-17	60.6
WP_146975129.1\|74794_75073_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_146975131.1\|75122_75728_+	hypothetical protein	Q6SEA6	Lactobacillus_prophage	3.2e-07	59.2
WP_146975134.1\|75798_76176_+	PH domain-containing protein	NA	NA	NA	NA
WP_146975136.1\|76293_77361_+\|integrase	tyrosine-type recombinase/integrase	E3W8I1	Leuconostoc_phage	6.1e-139	68.4
WP_029509760.1\|77697_77898_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.1e-22	78.5
80945:80959	attR	NA	NA	NA	NA

DBSCAN-SWA_3

92832 : 100470

Lactococcus_phage(33.33%)

integrase

attL 95391:95405|attR 98505:98519

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146975170.1\|92832_93843_+	Abi family protein	A0A0N7IRA5	Lactobacillus_phage	6.2e-24	30.8
WP_146975172.1\|94043_95222_+\|integrase	tyrosine-type recombinase/integrase	Q4ZCC1	Staphylococcus_virus	1.0e-09	24.6
95391:95405	attL	NA	NA	NA	NA
WP_146975174.1\|95460_96441_-\|integrase	tyrosine-type recombinase/integrase	A0A097BYJ7	Leuconostoc_phage	3.2e-150	79.2
WP_146977282.1\|96929_97229_+	type II toxin-antitoxin system MqsR family toxin	Q9AZG1	Lactococcus_phage	6.3e-09	39.4
WP_146975176.1\|97244_98126_+	DUF4065 domain-containing protein	Q9AZG0	Lactococcus_phage	5.6e-45	36.0
WP_010002267.1\|98631_100470_-	translational GTPase TypA	E4ZFJ7	Streptococcus_phage	7.3e-23	29.5
98505:98519	attR	NA	NA	NA	NA

DBSCAN-SWA_4

269246 : 282438

Bacillus_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010003305.1\|269246_270017_-	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.1e-16	29.1
WP_010003307.1\|270013_270853_-	phosphate ABC transporter ATP-binding protein	F2Y302	Organic_Lake_phycodnavirus	3.8e-11	28.8
WP_146975442.1\|270935_271820_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_029509636.1\|271819_272743_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_146975445.1\|272838_273720_-	phosphate ABC transporter substrate-binding protein PstS family protein	E3SLK5	Synechococcus_phage	5.1e-06	27.3
WP_146975447.1\|273825_275181_-	histidine kinase	W8CYF6	Bacillus_phage	6.2e-27	34.5
WP_077281817.1\|275249_276158_-	phosphate ABC transporter substrate-binding protein	H6WG65	Cyanophage	3.5e-10	27.0
WP_029509632.1\|276336_277026_-	response regulator transcription factor	Q56AR1	Bacillus_thuringiensis_phage	8.0e-07	33.0
WP_029509631.1\|277140_278286_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.2e-116	65.3
WP_146975449.1\|278418_279000_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_146975452.1\|279009_279888_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_146975454.1\|279901_281173_-	insulinase family protein	A0A2K9V7S4	Bandra_megavirus	9.6e-14	30.7
WP_146977288.1\|281169_282438_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	2.5e-46	31.8

DBSCAN-SWA_5

498242 : 507437

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048700949.1\|498242_499010_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.0e-23	32.4
WP_019041830.1\|499056_499701_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	3.0e-48	45.2
WP_010001491.1\|500131_501124_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.1e-49	35.9
WP_146975717.1\|501169_501901_-	acyl-ACP thioesterase	NA	NA	NA	NA
WP_048700955.1\|501941_502817_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	9.3e-77	55.7
WP_048700957.1\|502818_503739_-	DNA polymerase III subunit delta	M1NSC1	Streptococcus_phage	3.1e-06	25.2
WP_010004628.1\|503738_504068_-	hypothetical protein	NA	NA	NA	NA
WP_010004629.1\|504064_504718_-	dTMP kinase	M1PSC7	Streptococcus_phage	3.5e-52	51.4
WP_010004630.1\|504765_505026_-	YaaL family protein	NA	NA	NA	NA
WP_048700962.1\|505022_505628_-	recombination protein RecR	NA	NA	NA	NA
WP_146975719.1\|505664_507437_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	8.5e-53	42.8

DBSCAN-SWA_6

719850 : 780637

Lactobacillus_phage(19.23%)

capsid,tail,integrase,protease,head,portal,tRNA,terminase

attL 766801:766819|attR 780693:780711

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146975941.1\|719850_721098_+\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	1.2e-77	41.3
WP_146975943.1\|721171_722161_+	D-2-hydroxyacid dehydrogenase	M1HTA3	Paramecium_bursaria_Chlorella_virus	1.3e-37	30.6
WP_146975946.1\|722335_723205_+	NAD-binding protein	A0A077SLF7	Escherichia_phage	5.2e-19	27.0
WP_146975948.1\|723277_724267_+	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_146975950.1\|724528_725020_+	hypothetical protein	NA	NA	NA	NA
WP_146975953.1\|724965_725838_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_146975955.1\|725834_726560_+	response regulator	NA	NA	NA	NA
WP_146975957.1\|726661_728518_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_068851223.1\|728616_729435_+	HAD-IIB family hydrolase	NA	NA	NA	NA
WP_048699897.1\|729431_730340_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_010006252.1\|731267_732329_+	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	3.2e-63	37.7
WP_009999965.1\|732814_733204_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010006258.1\|733200_734106_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.2e-19	29.9
WP_146975960.1\|734102_734924_+	hypothetical protein	NA	NA	NA	NA
WP_146975962.1\|734949_735855_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	5.5e-40	41.0
WP_146975977.1\|735858_736623_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_048699884.1\|736713_737574_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.3e-50	39.1
WP_146975979.1\|737720_738605_-	zinc ABC transporter solute-binding protein	NA	NA	NA	NA
WP_146975982.1\|738601_739042_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_029509965.1\|739365_740379_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.3e-15	29.0
WP_048699877.1\|740375_741365_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-16	28.8
WP_009999951.1\|741367_742333_+	ABC transporter permease	NA	NA	NA	NA
WP_048699875.1\|742342_743230_+	ABC transporter permease	NA	NA	NA	NA
WP_146975984.1\|743338_745195_+	peptide-binding protein	NA	NA	NA	NA
WP_146975987.1\|745389_746850_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	5.7e-63	31.8
WP_146975989.1\|747084_747963_-	alpha/beta hydrolase fold domain-containing protein	NA	NA	NA	NA
WP_146975992.1\|747967_748753_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_146975994.1\|748774_749734_-	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_146975996.1\|749973_751272_+	MFS transporter	NA	NA	NA	NA
WP_146975999.1\|751268_752045_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_146977310.1\|752061_753060_+	substrate-binding domain-containing protein	C6ZCU4	Enterobacteria_phage	1.5e-17	25.0
WP_048699864.1\|753860_755216_+	sodium:proton antiporter	NA	NA	NA	NA
WP_146976001.1\|755358_755817_+	Tellurite resistance protein	NA	NA	NA	NA
WP_068851152.1\|755942_756599_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_146976004.1\|756618_758436_+	DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	1.1e-76	34.8
WP_146976007.1\|758721_760191_+	MFS transporter	NA	NA	NA	NA
WP_146976009.1\|760231_761920_+	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_048699852.1\|762161_763331_+	ROK family protein	NA	NA	NA	NA
WP_048699848.1\|765094_766609_+	xylulokinase	NA	NA	NA	NA
766801:766819	attL	NA	NA	NA	NA
WP_146976012.1\|767204_767804_+	hypothetical protein	NA	NA	NA	NA
WP_146976014.1\|767793_768159_+	hypothetical protein	NA	NA	NA	NA
WP_146976016.1\|768158_768572_+	hypothetical protein	A0A2D1GPE1	Lactobacillus_phage	1.3e-09	38.6
WP_146976018.1\|768647_768929_-	hypothetical protein	NA	NA	NA	NA
WP_146976020.1\|768934_769546_-	helix-turn-helix domain-containing protein	L0P7E1	Lactobacillus_phage	4.9e-08	45.9
WP_146976022.1\|769677_769884_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_146976024.1\|769971_771264_+	virulence protein E	A0A1B0Y896	Lactobacillus_phage	1.6e-93	46.0
WP_146976027.1\|771533_771728_+	hypothetical protein	NA	NA	NA	NA
WP_146976029.1\|771714_772047_+	hypothetical protein	NA	NA	NA	NA
WP_146976031.1\|772050_772461_+	DUF722 domain-containing protein	A0A097BYG4	Leuconostoc_phage	1.8e-14	34.7
WP_146976033.1\|772536_773037_+	HNH endonuclease	Q9AZM8	Lactococcus_phage	1.2e-47	54.8
WP_146976035.1\|773229_773706_+\|terminase	phage terminase small subunit P27 family	Q5K5J8	Oenococcus_phage	8.8e-13	40.2
WP_146976037.1\|773702_775538_+\|terminase	terminase large subunit	Q9AZM6	Lactococcus_phage	1.3e-208	59.8
WP_146976039.1\|775711_776785_+\|portal	phage portal protein	Q9AZM4	Lactococcus_phage	6.6e-109	56.6
WP_146976041.1\|776781_777342_+\|head,protease	HK97 family phage prohead protease	Q9AZM3	Lactococcus_phage	3.5e-45	54.8
WP_146976043.1\|777352_778525_+\|capsid	phage major capsid protein	A0A2H4J7D0	uncultured_Caudovirales_phage	2.1e-52	44.3
WP_146976045.1\|778580_778880_+\|head,tail	phage gp6-like head-tail connector protein	A0A2P0ZLF2	Lactobacillus_phage	1.2e-07	37.6
WP_146977312.1\|778872_779223_+\|head	phage head closure protein	Q9AZM0	Lactococcus_phage	1.4e-20	47.7
WP_146976047.1\|779219_779408_+	hypothetical protein	A0A097BYD9	Leuconostoc_phage	9.1e-22	82.1
WP_146976049.1\|779509_780637_+\|integrase	tyrosine-type recombinase/integrase	A0A097BYJ7	Leuconostoc_phage	8.4e-179	81.6
780693:780711	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1377436 : 1430068

Leuconostoc_phage(41.03%)

capsid,tail,integrase,portal,tRNA,terminase

attL 1369928:1369945|attR 1437004:1437021

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1369928:1369945	attL	NA	NA	NA	NA
WP_146976657.1\|1377436_1378642_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.3e-41	47.5
WP_010004311.1\|1378634_1379135_+	dihydrofolate reductase	A0A0N9S8H6	Staphylococcus_phage	2.2e-22	38.3
WP_029509285.1\|1379142_1379994_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.6e-12	41.6
WP_146976659.1\|1380072_1380828_+	SGNH/GDSL hydrolase family protein	Q8LTH0	Staphylococcus_virus	1.7e-42	43.1
WP_146976661.1\|1380862_1381894_-	beta-propeller fold lactonase family protein	NA	NA	NA	NA
WP_146976663.1\|1382016_1383180_+	DNA repair exonuclease	NA	NA	NA	NA
WP_146976665.1\|1383185_1385549_+	AAA family ATPase	NA	NA	NA	NA
WP_048701787.1\|1385564_1386512_+	HD domain-containing protein	NA	NA	NA	NA
WP_146976667.1\|1386544_1387456_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_146976669.1\|1387510_1387750_-	hypothetical protein	NA	NA	NA	NA
WP_146976671.1\|1387755_1388187_-	HIT domain-containing protein	D7NW73	Streptomyces_phage	2.4e-09	34.1
WP_146976674.1\|1388257_1389001_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.1e-20	31.6
WP_146976676.1\|1388951_1390259_+	ABC transporter permease	NA	NA	NA	NA
WP_048701895.1\|1390306_1390966_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_146976678.1\|1391005_1392094_-\|integrase	tyrosine-type recombinase/integrase	Q9ZXG6	Leuconostoc_phage	1.6e-41	33.7
WP_146976680.1\|1392263_1392890_-	hypothetical protein	NA	NA	NA	NA
WP_146976682.1\|1392941_1393361_-	ImmA/IrrE family metallo-endopeptidase	E3W8B8	Leuconostoc_phage	2.0e-29	48.9
WP_146977346.1\|1393357_1393720_-	helix-turn-helix domain-containing protein	E3W8B9	Leuconostoc_phage	2.5e-20	47.5
WP_146976684.1\|1393995_1394199_+	hypothetical protein	NA	NA	NA	NA
WP_146976686.1\|1394210_1394981_+	phage antirepressor Ant	A0A075KJT3	Lactobacillus_phage	1.1e-70	57.9
WP_146976688.1\|1394970_1395231_+	hypothetical protein	NA	NA	NA	NA
WP_146976690.1\|1395347_1395587_+	hypothetical protein	A0A097BYE5	Leuconostoc_phage	2.8e-15	53.2
WP_146976692.1\|1395586_1395784_+	helix-turn-helix domain-containing protein	G3MBD2	Bacillus_virus	8.1e-05	43.8
WP_146976694.1\|1395773_1395974_+	hypothetical protein	NA	NA	NA	NA
WP_146976697.1\|1395974_1396772_+	DNA replication protein	E9LUM6	Lactobacillus_phage	1.4e-50	49.2
WP_146976699.1\|1396775_1397054_+	hypothetical protein	NA	NA	NA	NA
WP_146976701.1\|1397116_1398031_+	DUF1351 domain-containing protein	NA	NA	NA	NA
WP_146976704.1\|1398027_1398651_+	hypothetical protein	D2JGK1	Staphylococcus_phage	6.8e-13	33.5
WP_146976706.1\|1398637_1399051_+	single-stranded DNA-binding protein	A0A097BYB0	Leuconostoc_phage	2.7e-58	81.8
WP_146976709.1\|1399062_1399776_+	hypothetical protein	A0A097BYG8	Leuconostoc_phage	8.9e-110	82.8
WP_055308143.1\|1399738_1399921_+	hypothetical protein	NA	NA	NA	NA
WP_146976711.1\|1399925_1400384_+	RusA family crossover junction endodeoxyribonuclease	A0A097BYB3	Leuconostoc_phage	9.2e-60	77.6
WP_146976714.1\|1400367_1400649_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_146976716.1\|1400645_1400930_+	hypothetical protein	NA	NA	NA	NA
WP_146976718.1\|1400926_1401118_+	hypothetical protein	A0A097BYH8	Leuconostoc_phage	1.7e-23	85.2
WP_055308135.1\|1401120_1401339_+	hypothetical protein	NA	NA	NA	NA
WP_146976720.1\|1401381_1401804_+	DUF722 domain-containing protein	E3W8E2	Leuconostoc_phage	7.5e-08	31.6
WP_146976723.1\|1403106_1404171_+	DUF4747 family protein	NA	NA	NA	NA
WP_146976725.1\|1404190_1404754_+	hypothetical protein	NA	NA	NA	NA
WP_146976728.1\|1405351_1405903_+	hypothetical protein	NA	NA	NA	NA
WP_146976730.1\|1405960_1406470_+\|terminase	terminase small subunit	A0A097BYC9	Leuconostoc_phage	6.7e-51	72.4
WP_146976732.1\|1406453_1407779_+\|terminase	PBSX family phage terminase large subunit	A0A286QNX6	Streptococcus_phage	3.5e-160	63.6
WP_146976735.1\|1407787_1409281_+\|portal	phage portal protein	M1IFC5	Streptococcus_phage	3.9e-131	47.2
WP_146976738.1\|1409283_1410477_+\|capsid	capsid protein	M1IEV1	Streptococcus_phage	2.9e-73	40.4
WP_146976741.1\|1410583_1411195_+	hypothetical protein	NA	NA	NA	NA
WP_146976743.1\|1411197_1412028_+\|capsid	N4-gp56 family major capsid protein	A8ASJ6	Listeria_phage	5.2e-93	65.8
WP_146976745.1\|1412039_1412282_+	hypothetical protein	NA	NA	NA	NA
WP_146976747.1\|1412319_1412709_+	hypothetical protein	A0A1S5SE16	Streptococcus_phage	7.0e-08	34.6
WP_146976750.1\|1412629_1413043_+	hypothetical protein	NA	NA	NA	NA
WP_055308624.1\|1413042_1413384_+\|capsid	capsid protein	A0A1P8VVL8	Streptococcus_phage	5.0e-26	53.6
WP_146976752.1\|1413383_1413782_+	hypothetical protein	A0A2H4JHL9	uncultured_Caudovirales_phage	1.7e-14	36.2
WP_146976755.1\|1413781_1414249_+\|tail	phage tail protein	Q938K6	Temperate_phage	1.4e-34	49.7
WP_048701005.1\|1414290_1414629_+	hypothetical protein	NA	NA	NA	NA
WP_029509800.1\|1414630_1415200_+	hypothetical protein	A0A286QMS7	Streptococcus_phage	6.6e-31	37.1
WP_146976759.1\|1415192_1418078_+	tape measure protein	A0A191KBP6	Streptococcus_virus	1.6e-80	72.0
WP_146976761.1\|1418077_1418806_+	hypothetical protein	B3GW14	Streptococcus_phage	1.8e-33	32.5
WP_146976763.1\|1418802_1424124_+	hypothetical protein	B3GW15	Streptococcus_phage	1.1e-58	32.5
WP_146974999.1\|1424134_1424530_+	hypothetical protein	NA	NA	NA	NA
WP_146974997.1\|1424532_1424769_+	hypothetical protein	A0A097BYE3	Leuconostoc_phage	4.9e-33	93.6
WP_010004951.1\|1424770_1425037_+	hypothetical protein	A0A097BYC8	Leuconostoc_phage	1.7e-42	100.0
WP_146976765.1\|1425089_1425512_+	hypothetical protein	A0A097BYC6	Leuconostoc_phage	1.1e-59	92.0
WP_146976767.1\|1425523_1426465_+	N-acetylmuramoyl-L-alanine amidase	A0A097BY89	Leuconostoc_phage	6.8e-158	85.7
WP_055308107.1\|1426597_1426792_+	CsbD family protein	NA	NA	NA	NA
WP_146976770.1\|1426924_1428238_+	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.6e-88	40.0
WP_146976772.1\|1428230_1428617_+	hypothetical protein	E3W8I0	Leuconostoc_phage	1.4e-16	43.3
WP_146976774.1\|1428597_1428849_+	hypothetical protein	NA	NA	NA	NA
WP_146976776.1\|1429501_1430068_-	hypothetical protein	E3W8I2	Leuconostoc_phage	2.9e-15	45.7
1437004:1437021	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1562055 : 1632487

Staphylococcus_phage(18.75%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146976967.1\|1562055_1562364_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_146976969.1\|1562490_1563330_-	hypothetical protein	NA	NA	NA	NA
WP_146976971.1\|1563585_1563846_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_146976973.1\|1563976_1565515_+	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_146976975.1\|1565633_1567556_+	hypothetical protein	NA	NA	NA	NA
WP_146976977.1\|1567738_1568140_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_146976979.1\|1571904_1572807_+	methionine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_146976981.1\|1575253_1575511_+	hypothetical protein	NA	NA	NA	NA
WP_146976983.1\|1575571_1575994_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_146976985.1\|1576020_1577397_+	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	5.5e-39	30.0
WP_146976987.1\|1577396_1577708_+	hypothetical protein	NA	NA	NA	NA
WP_146975332.1\|1577970_1578891_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.6e-40	38.2
WP_141309055.1\|1579373_1580408_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	4.7e-35	31.3
WP_048702259.1\|1580833_1581025_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_068852693.1\|1581037_1581403_-	DUF3796 domain-containing protein	NA	NA	NA	NA
WP_146976989.1\|1581948_1584837_-	hypothetical protein	NA	NA	NA	NA
WP_146976991.1\|1585024_1585906_-	sortase	NA	NA	NA	NA
WP_146976993.1\|1585919_1588052_-	hypothetical protein	NA	NA	NA	NA
WP_068852706.1\|1588069_1588456_-	hypothetical protein	NA	NA	NA	NA
WP_141309048.1\|1588573_1589167_-	hypothetical protein	NA	NA	NA	NA
WP_146976995.1\|1589168_1589738_-	hypothetical protein	NA	NA	NA	NA
WP_146976997.1\|1589737_1590139_-	thioredoxin fold domain-containing protein	NA	NA	NA	NA
WP_146976999.1\|1590224_1591469_-	peptidoglycan DD-metalloendopeptidase family protein	A0A140G6T8	Arthrobacter_phage	1.3e-07	35.9
WP_146977001.1\|1591481_1593440_-	type IV secretion system protein VirB4	NA	NA	NA	NA
WP_146977003.1\|1593442_1594099_-	hypothetical protein	NA	NA	NA	NA
WP_141309043.1\|1594105_1594423_-	hypothetical protein	NA	NA	NA	NA
WP_146977005.1\|1594739_1595519_+	AAA family ATPase	A0A0K2FLP4	Brevibacillus_phage	9.0e-15	38.7
WP_068853142.1\|1595518_1595806_+	hypothetical protein	NA	NA	NA	NA
WP_068852736.1\|1595866_1596382_-	hypothetical protein	NA	NA	NA	NA
WP_146977008.1\|1596417_1598502_-	hypothetical protein	NA	NA	NA	NA
WP_146977011.1\|1598502_1601475_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_146977014.1\|1601458_1603342_-	AAA domain-containing protein	H6X3M6	Enterobacteria_phage	1.2e-68	31.9
WP_146977017.1\|1603331_1603826_-	hypothetical protein	NA	NA	NA	NA
WP_146977019.1\|1603838_1606097_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_146977022.1\|1606086_1606347_-	hypothetical protein	NA	NA	NA	NA
WP_146977024.1\|1606833_1607475_+	hypothetical protein	NA	NA	NA	NA
WP_048702090.1\|1607492_1607723_+	hypothetical protein	NA	NA	NA	NA
WP_048702087.1\|1608446_1608878_+	hypothetical protein	NA	NA	NA	NA
WP_146977026.1\|1609328_1609556_+	hypothetical protein	NA	NA	NA	NA
WP_080973687.1\|1609719_1609950_+	hypothetical protein	NA	NA	NA	NA
WP_146977029.1\|1609952_1610222_+	hypothetical protein	NA	NA	NA	NA
WP_146977031.1\|1610227_1610488_-	hypothetical protein	NA	NA	NA	NA
WP_146977034.1\|1610474_1610852_-	hypothetical protein	E3W8I0	Leuconostoc_phage	1.0e-16	40.5
WP_146977362.1\|1610844_1612158_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	9.3e-89	39.7
WP_146977036.1\|1612283_1613603_+	hypothetical protein	NA	NA	NA	NA
WP_146977039.1\|1613623_1614187_-	hypothetical protein	NA	NA	NA	NA
WP_146977041.1\|1614438_1614783_-	hypothetical protein	NA	NA	NA	NA
WP_146977044.1\|1615012_1616251_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.3e-20	33.7
WP_146977046.1\|1616243_1617839_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	8.0e-127	50.8
WP_146977048.1\|1617838_1620910_-	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	5.5e-23	22.9
WP_146977050.1\|1621576_1622263_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.1e-61	52.2
WP_146977364.1\|1622580_1624653_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.5e-64	31.8
WP_146977053.1\|1624947_1625100_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_029510500.1\|1625112_1625568_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_146977055.1\|1627160_1628492_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_146977057.1\|1628569_1629541_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.7e-23	31.7
WP_029510506.1\|1629541_1631068_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_146977060.1\|1631392_1632238_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.5e-31	35.2
WP_004912700.1\|1632244_1632487_-\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	1.6e-07	38.2

DBSCAN-SWA_9

1635842 : 1684342

Staphylococcus_prophage(33.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146977063.1\|1635842_1636529_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	1.5e-61	51.3
WP_146977065.1\|1636850_1637483_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.1e-23	36.6
WP_146977068.1\|1638008_1638572_-	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	2.4e-33	44.1
WP_101913440.1\|1638802_1639018_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	9.4e-15	67.7
WP_146977071.1\|1639263_1639482_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_146977074.1\|1639474_1639864_-	hypothetical protein	NA	NA	NA	NA
WP_029510464.1\|1639920_1640769_-	methionine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_146977076.1\|1640826_1642119_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_146977078.1\|1643465_1643726_+	hypothetical protein	NA	NA	NA	NA
WP_146977082.1\|1644875_1646372_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_146977084.1\|1646340_1646655_-	hypothetical protein	NA	NA	NA	NA
WP_146977086.1\|1646647_1647328_-	hypothetical protein	NA	NA	NA	NA
WP_146977089.1\|1647348_1648140_-	DNA-entry nuclease	NA	NA	NA	NA
WP_146977091.1\|1648199_1648541_-	hypothetical protein	NA	NA	NA	NA
WP_146977093.1\|1648758_1649751_-	hypothetical protein	NA	NA	NA	NA
WP_146977096.1\|1649754_1650189_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_048702239.1\|1650169_1650517_-	hypothetical protein	NA	NA	NA	NA
WP_146977098.1\|1650488_1650761_-	hypothetical protein	NA	NA	NA	NA
WP_146977367.1\|1650780_1651746_-	replication initiator protein A	A0A286QNA4	Streptococcus_phage	6.3e-18	47.4
WP_146977100.1\|1651748_1652003_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_146977369.1\|1653992_1654124_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_146977102.1\|1654118_1654529_-	hypothetical protein	NA	NA	NA	NA
WP_146977104.1\|1654658_1655333_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.7e-30	38.1
WP_146977107.1\|1655337_1656384_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_146977109.1\|1660628_1661774_-	class C sortase	NA	NA	NA	NA
WP_146977111.1\|1661766_1662945_-	class C sortase	NA	NA	NA	NA
WP_146977113.1\|1663081_1664608_-	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_146977115.1\|1664604_1665702_-	hypothetical protein	NA	NA	NA	NA
WP_146977117.1\|1665701_1668383_-	VWA domain-containing protein	NA	NA	NA	NA
WP_146975332.1\|1668520_1669441_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.6e-40	38.2
WP_146977119.1\|1669910_1671023_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_146977121.1\|1671262_1671532_-	hypothetical protein	NA	NA	NA	NA
WP_050895532.1\|1671620_1671815_-	hypothetical protein	NA	NA	NA	NA
WP_146977123.1\|1671887_1673540_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011679788.1\|1673926_1674223_-	hypothetical protein	NA	NA	NA	NA
WP_146975332.1\|1674361_1675282_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.6e-40	38.2
WP_146977125.1\|1676158_1676530_-	hypothetical protein	NA	NA	NA	NA
WP_146977127.1\|1677635_1678139_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_146977129.1\|1678185_1680696_-	DUF3533 domain-containing protein	NA	NA	NA	NA
WP_080987728.1\|1680799_1680985_-	hypothetical protein	NA	NA	NA	NA
WP_146977123.1\|1681057_1682710_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011679788.1\|1683096_1683393_-	hypothetical protein	NA	NA	NA	NA
WP_146975332.1\|1683421_1684342_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.6e-40	38.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage