CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP019840	Leptotrichia trevisanii strain JMUB3935	3 crisprs	csa3,PD-DExK,DinG,DEDDh,RT,cas3,WYL,cas10,csx10gr5,csm3gr7,cas6,cas2,cas4,csx20,csx1	0	0	2	6

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP019840_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019840_1

1354470-1355032

TypeIII

I-B

Consensus_repeat	Method
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	PILER-CR
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CRISPRCasFinder
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAT	CRT

7 spacers

The CRISPR arrays of NZ_AP019840_1

>merge|NZ_AP019840|1|1354470-1355032|PILER-CR,CRISPRCasFinder,CRT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACGTTGTACAAAGTTACTATAAAATGAAATTAGATGGATTGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAATTTCAGAGCAGCTTTATGACTTTTAAATATATTAAGGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACATTTTTCGATTGCTCCTGTTACATCAAATTTCATTTTGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACTATAGGAAGAGTGTGGGAATTGATGAAGTCTATGAAGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACATCTAACATCACTAACTAGATCTGAGAAAGGATAATCGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACATGATGATGGAGGTAACGTAGTAGATGGTGTTAAACCTCAAGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACATCTTCGTAATTCTTTTTAACATGTTCTAACTTAGTAGGTTAAAGTAAGTTATCCATTAAAATAAGGTTTAGAAAAT

>NZ_AP019840|1|1|1354470-1354955|PILER-CR
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	GTTGTACAAAGTTACTATAAAATGAAATTAGATGGATT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AATTTCAGAGCAGCTTTATGACTTTTAAATATATTAAG
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTTTTCGATTGCTCCTGTTACATCAAATTTCATTTT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TATAGGAAGAGTGTGGGAATTGATGAAGTCTATGAA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATCTAACATCACTAACTAGATCTGAGAAAGGATAATC
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATGATGATGGAGGTAACGTAGTAGATGGTGTTAAACCTCAA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC

>NZ_AP019840|1|1|1354470-1355030|CRISPRCasFinder
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	GTTGTACAAAGTTACTATAAAATGAAATTAGATGGATT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AATTTCAGAGCAGCTTTATGACTTTTAAATATATTAAG
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTTTTCGATTGCTCCTGTTACATCAAATTTCATTTT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TATAGGAAGAGTGTGGGAATTGATGAAGTCTATGAA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATCTAACATCACTAACTAGATCTGAGAAAGGATAATC
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATGATGATGGAGGTAACGTAGTAGATGGTGTTAAACCTCAA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATCTTCGTAATTCTTTTTAACATGTTCTAACTTAGTAG
GTTAAAGTAAGTTATCCATTAAAATAAGGTTTAGAAA

>NZ_AP019840|1|1|1354470-1355032|CRT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACGT	TGTACAAAGTTACTATAAAATGAAATTAGATGGATT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAA	TTTCAGAGCAGCTTTATGACTTTTAAATATATTAAG
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAT	TTTTCGATTGCTCCTGTTACATCAAATTTCATTTT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACTA	TAGGAAGAGTGTGGGAATTGATGAAGTCTATGAA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAT	CTAACATCACTAACTAGATCTGAGAAAGGATAATC
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAT	GATGATGGAGGTAACGTAGTAGATGGTGTTAAACCTCAA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAT	CTTCGTAATTCTTTTTAACATGTTCTAACTTAGTAG
GTTAAAGTAAGTTATCCATTAAAATAAGGTTTAGAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019840.1\|WP_018450081.1\|1364418_1364994_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_AP019840.1\|WP_146996572.1\|1361066_1362764_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_AP019840.1\|WP_146997763.1\|1356986_1357508_+\|DUF448-domain-containing-protein	unknown	unknown	gnl\|CDD\|225350
NZ_AP019840.1\|WP_026748986.1\|1350680_1351037_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_AP019840.1\|WP_146996563.1\|1346152_1347967_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379114
NZ_AP019840.1\|WP_146996566.1\|1349692_1350640_-\|zinc-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238500
NZ_AP019840.1\|WP_146996574.1\|1362821_1364108_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NZ_AP019840.1\|WP_026748984.1\|1353025_1353919_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_AP019840.1\|WP_146996571.1\|1360604_1360973_+\|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl\|CDD\|376719
NZ_AP019840.1\|WP_146996565.1\|1348942_1349641_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224046
NZ_AP019840.1\|WP_146996570.1\|1357504_1360582_+\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NZ_AP019840.1\|WP_172619081.1\|1353963_1354128_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146996567.1\|1351301_1352894_+\|phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|237436
NZ_AP019840.1\|WP_146996576.1\|1365325_1366555_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NZ_AP019840.1\|WP_146996561.1\|1344215_1344947_+\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|377151
NZ_AP019840.1\|WP_146996562.1\|1345091_1346129_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|177398
NZ_AP019840.1\|WP_146996564.1\|1348057_1348900_-\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NZ_AP019840.1\|WP_146996577.1\|1366622_1368989_+\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NZ_AP019840.1\|WP_146996568.1\|1355183_1355672_+\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NZ_AP019840.1\|WP_146996569.1\|1355671_1356865_+\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|237061

Protein	Function_ID	Function_description	E-value
NZ_AP019840.1\|WP_018450081.1\|1364418_1364994_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	7.03625e-135
NZ_AP019840.1\|WP_146996572.1\|1361066_1362764_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.14219e-132
NZ_AP019840.1\|WP_146997763.1\|1356986_1357508_+\|DUF448-domain-containing-protein	gnl\|CDD\|225350	COG2740, COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription].	6.13057e-09
NZ_AP019840.1\|WP_026748986.1\|1350680_1351037_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	1.86944e-19
NZ_AP019840.1\|WP_146996563.1\|1346152_1347967_+\|AAA-family-ATPase	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.40042e-08
NZ_AP019840.1\|WP_146996566.1\|1349692_1350640_-\|zinc-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238500	cd01018, ZntC, Metal binding protein ZntC. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and bind their specific ligands in the cleft between these domains. In addition, many of these proteins possess a metal-binding histidine-rich motif (repetitive HDH sequence).	2.41915e-67
NZ_AP019840.1\|WP_146996574.1\|1362821_1364108_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	4.29122e-122
NZ_AP019840.1\|WP_026748984.1\|1353025_1353919_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	5.38516e-103
NZ_AP019840.1\|WP_146996571.1\|1360604_1360973_+\|30S-ribosome-binding-factor-RbfA	gnl\|CDD\|376719	pfam02033, RBFA, Ribosome-binding factor A.	6.29321e-23
NZ_AP019840.1\|WP_146996565.1\|1348942_1349641_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	2.64656e-70
NZ_AP019840.1\|WP_146996570.1\|1357504_1360582_+\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_AP019840.1\|WP_146996567.1\|1351301_1352894_+\|phosphoglycerate-dehydrogenase	gnl\|CDD\|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_AP019840.1\|WP_146996576.1\|1365325_1366555_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_AP019840.1\|WP_146996561.1\|1344215_1344947_+\|peroxide-stress-protein-YaaA	gnl\|CDD\|377151	pfam03883, H2O2_YaaD, Peroxide stress protein YaaA. YaaA is a key element of the stress response to H2O2. It acts by reducing the level of intracellular iron levels after peroxide stress, thereby attenuating the Fenton reaction and the DNA damage that this would cause. The molecular mechanism of action is not known.	2.04881e-71
NZ_AP019840.1\|WP_146996562.1\|1345091_1346129_+\|hypothetical-protein	gnl\|CDD\|177398	PHA02569, 39, DNA topoisomerase II large subunit; Provisional.	0.00697188
NZ_AP019840.1\|WP_146996564.1\|1348057_1348900_-\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	9.78471e-49
NZ_AP019840.1\|WP_146996577.1\|1366622_1368989_+\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NZ_AP019840.1\|WP_146996568.1\|1355183_1355672_+\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	3.36873e-41
NZ_AP019840.1\|WP_146996569.1\|1355671_1356865_+\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	1.79636e-143

>NZ_AP019840.1|WP_172619081.1|1353963_1354128_+|hypothetical-protein
MAIIVKKGELAKINKGMSQKGFAERCTYTVKKFPKSNLSKKAEEALNKIFSSMK
>NZ_AP019840.1|WP_026748984.1|1353025_1353919_+|homoserine-kinase
MGLKFKVKVPGTSANIGVGYDCLGVALDYFLELEVEESDKIEFLENGEPFSIPIEENLIFEAIKYTEKHLVKNIPSYKVNIVKNDIPISRGLGSSSSAIVAGILIANKFAGDVLDINEVAKLAVEMEGHPDNVVPAIFGGMVLTAHDKENLVYSSLINSDDLCFYVMIPDFKLSTEKARSVLPKMYLVSDAINNISKLGLLVNAFNKGEYDNLRFLLGDKIHQPYRFALINDSKKIFEASKKHGALGEYISGAGPTLISLNYDNEEFLENMKKELAELSDNWTIEKKKINLKGAEVY
>NZ_AP019840.1|WP_146996567.1|1351301_1352894_+|phosphoglycerate-dehydrogenase
MYRVLVGEYIDDEAIAGLQEARDVKVDVKVGISREEILDIIGEYDALIVRSVIKVDKELLDKAKNLKIVGRAGNGTDNINIPEATAHGVIVANTPDSNTVSACEIAIGLMIASARNIVAANNFIKSGKWEREIFVGNELFEKTLGIIGLGRIGGLVATRMKAFGMKLVAYDPYISDERFKRYSCEKAKTLDELMEKADVITIHTPKTKETVDMINAENLHKLKDGVRLVNAARGGLFNEEAVAEGLRSGKITSFGYDVHTVEPRSECILYEFENAITTPHIGATTYEAQRNVGTQVVKQVLNGLRGEIVETAVNLPAIGREEFLIVKPFINLAEKLGKIYFQIEKTPITNVVLNYYGEIAEQETALVDSTAIKGILEPVLKEEVNYINSKPLAEKRGINISINKKEHKYKNYSSAIEFVITNEEGKKIYVVGTIGMNNEERIISIKNHDVDMAISDNMIYLGNDDVPGVIGAVGATLGKENINIATMNVGRRENSAIMLLTVDSEVGRRSLKELRGLSQIKWAYYLDLTI
>NZ_AP019840.1|WP_026748986.1|1350680_1351037_-|transcriptional-repressor
MKLTKKRQKIFELVQASNNPVNAKFLKSQVDFDLSTVYRALEFLEKNNYIFSFDFENEKYYFKEENANFFICDSCKHIETVPEFSNEETEKEKSELKKRGFSLLSHLSIFKGKCNDCD
>NZ_AP019840.1|WP_146996566.1|1349692_1350640_-|zinc-ABC-transporter-substrate-binding-protein
MKKLLSLLLLSALFIFSCGNKSETKKEQGTTGGAKEKIVTSVPPLRWLTQKIAGDDFEVISIVQPNMNHELFEPKPSDLKILENSKVFFTYNMLGFEETISDSLSDKNKIVNVLDGVDKNLFIKGDHDHDHDHEHEHGHEHGKKEEHEHHHEHEGHGGIDPHVWFSLDMMPKVAENIKNELSKLYPDKKETFEKNYNAFITELNQVKAELSQKMASKTKKSFMIYHPALNYFLKNYAIEEISIEQEGKEPSAQQIKEIIDEAKEHNVTTILVQPQFPKQSAEAISKEIPNSKVAEFNVDKENVFENLKQFVDYLN
>NZ_AP019840.1|WP_146996565.1|1348942_1349641_-|ATP-binding-cassette-domain-containing-protein
MANGQNKKLVSVRNLNFKYKNDYILNDINLDIFKGKNVAILGRNGGGKSTLVKVMLGFLRKNSGSIEFFTNENKIGYLPQIREFDTSFPINIFDLVISGLTNKNNLFRRFNNEEKKRAEILLKEFDIFHLKNKLINEVSGGQLQRALIARALISSPELIFLDEPESFLDKEFEFKLFEKIKELSDSTIVVISHELEKIYDYIDSIFVVEGNIRVYEKKEDYVCSNPYLHSHK
>NZ_AP019840.1|WP_146996564.1|1348057_1348900_-|metal-ABC-transporter-permease
MEFIKIFEYAFMRNALVVGLLSSICCGIIGTYIVNKKMVFISSSISHASYGGIGIGIYLIYFFNLPIKDPLFFGLIFSILSGILILVLKDTLHVDGDLGIGIVMSMGMAIGIIFAFLTPGYQSDMSTYLFGNILLSNTLNIILLLILDIITITFFIIFYKSIVYTSFDENFYKIHSVPVTFINYFMIILISSVIIINIKTIGIILIISILTIPQAIAASLARRYSTIIILSIIFSFIGILSGLYFSYTLNIPSGPSIIVLLTILLALVKIWGFVKGKFLN
>NZ_AP019840.1|WP_146996563.1|1346152_1347967_+|AAA-family-ATPase
MYVEDYKGLKDFEITFDNNYEVKYNRDKDTLSINKKCESANNNIENFYSIDKTKGNIDSVNLLIGKNGSGKTSVLEILISNLFDNIKRKTNCVICYKSGKGDETFICEKHLEVVKPRYYKNYIENTGMVKFLFKEATMNVIQREILSQKYAKLKTIYYKLNIGLGNGSKENVYNYLIKINQEKNNDNFENSHLTLTIPNLSEEFILEAQKVREIVRDLDFNDNIEDLVKLYDTNKNDLKDIILNNYFNFLYLEHISGNLNMGNEKIFSKKELKEKKNKVLKLLNNKSSSEKFKLLLKEIGKLESYGYIFYNYDEKEYEIIEKMSIFLEKIPKEEMVVSNSKIIKKFRINCKDKNKEIIELLKKYDLFHILDTEKKGKDSINYLSLKNLEFIKIEEEGLSDGERIKLQYFSTLHGVLNGEFKDREYITLLFDEVESFLHPEWSRRFLYELIEELERYEDKKFKLIFATHSPFLIADVLAKDCIYLSKDKEGKIKAEIKEDLKTFGANIIDLFKNTMFLESTFGKFATEKIKGVVDKIEKAEKYSDIKHKVDFIIDEIGEKLISNKLKSMIESKFENKDEEYYRKKIEEYQEKLKKLGNKENDKNS
>NZ_AP019840.1|WP_146996562.1|1345091_1346129_+|hypothetical-protein
MIKIDVDKRKWEKIKEEHSEWYSDNILPNIKNAYEFIESQKSKSYSIKKYLELLKKIIDKGKDFIIQKELFLDYENKEIDKIIKIMKKKNKKSKSILEIRFEKLNISEEYLPNQLFCYKKLQTGNKDWNRHKLLSLIGIEICPYCQRNYISSYEENNSKKTTADLDHFYPKSLYPFLALSLYNFIPSCQICNSRFKGNKDVWGSVYPYEEGFDELGVKFRTSEEVIVEILGEGHSDFSVKIDYENLKDEKSKEKIKKSIRNLGLDKVYEKSHNQYIQNLLYNIEKYPENYLENCVEMFENDNDKKKQLEEYFKDIVKESYRKRIENGEPLAKLTKDILEEFNIKI
>NZ_AP019840.1|WP_146996561.1|1344215_1344947_+|peroxide-stress-protein-YaaA
MKIIISPSKTKKINNLPIKDSGSLTEKEPFYLEITKEIIEKIKTFSVEEIEKKFKLKNEKAQNLLGFYQNYENEKSGNALASYTGVAYKAIKIETFDKSDFEYLESHLVILSALYGVLTSYTNVKEYRLDMTNSIFESKSLYEVWKTSVNEYFEHEDIILNLASKEYSKLINPDKLIDFEFWEDSNGKLKQVSTNSKKMRGFTLNYIVKNKISDVKKLRNITLNGYVCDEDMSDERKFVYVKK
>NZ_AP019840.1|WP_146996568.1|1355183_1355672_+|ribosome-maturation-factor-RimP
MEQILDEFEKKIEQHLKKMNLELADLEYVRDGGYNYLRVYVEKLDGTTTLDDCIDFSREIDGIADDLIEEKFFLEVSTPGIERRLRKPKDFVRFSGERINVQAKSNIEGAKKFIGKLEKFENDTVFLLDDKLAKIVEIPLSKLKKANLIYELPNGILNSEEE
>NZ_AP019840.1|WP_146996569.1|1355671_1356865_+|transcription-termination/antitermination-protein-NusA
MKGRDQKIFLEALDELEKEKGILKEELLETIETALLAAYKKNYGEKDNVKVTINRNSGDVKVYSQRLIVENVENPDEEISLEDAISVKKRAKLGDILDLEINAESFKRNAIQNAKQIVVQKVRECEKRNIFNKFKEIENSIVSANVRKTDEKGNLYVDINGLEAIVPAKELSPVDIFRQGDRIKIYIGAVEESTKFTKTFVSRKSEELLRGLLELEVPEIYEEIIEIRNIAREAGSRSKVAVYSNDKNLDVKGACIGRNGMRIQNIIDELCGEKIDVVLWNEDITEFVKNALNPAEVLSVEIIEEGEENMKVARVLVAENQLSLAIGKKGQNSRLAARLCGVKIDIHTEAAKIEKYEENTAFNDSFEDEIENVGETSDSNDDYEVEESAFAGLHEEE
>NZ_AP019840.1|WP_146997763.1|1356986_1357508_+|DUF448-domain-containing-protein
MCICCRKKGEKSDFLRIAEQDGKYVFDKEMKIQARGFYVCKTNECIERLSKHKKYNIEMEQFVQMLEEVKKQKKNIIDILKPMKNSEYFVFGIDEVFEGIKREKIKLVIIPADIKAKYIDEFEKLKKNFNFEIIFIKKKEELIRLFSRDVNVIGIFNKKVIKGILSKVEVMNG
>NZ_AP019840.1|WP_146996570.1|1357504_1360582_+|translation-initiation-factor-IF-2
MKVHELAKENGFTATKFMEEIRKFGIDKKHHMNVLSDEEVSLIRKKLQKGVQNNQNNGKTENLNKSENKTTESTKENIVKMVSSHSDSQKNNNAEHSKISEHKNINKNYEKPKQPLEKDIKLNVEKKSDNSNINKSNLNNTKNLDNNKNQKFEKPNRFDKKENNKKMEMKVNLSSQNNKANELNREKQSFQNRDSRDSKDNRENGGRNFQNRDNRNREDRKEGFRKEGRDNFRRDNRNFNKDGNNQTRDNRDNRGFQNRDRDNQSGSRNFQSRDNRNREDRKEGFRKEGRDNFRRDNRNFNKDGNNQARDSRDNRGFQNRDRDNQSGGRNFRDRQDNRGFSDRGGFNKDRDDFRKDSRNFSNAKKETSSEIPAATVAEKGKAGGKGKGKFDKKKYEKNRRDREQQEKELRSDFRKDDKKKKKNKKQEKVVKDEIVRIEGESIGMITIGEEIVIKDLAEKLGINVSDIIKKFFMEGKLLTANAILSFEEAEEVALEYEVIVEKEVIEEISYGEKYQLEQEDTADELVTRAPVITIMGHVDHGKTSLLDALRHTNVMSDEAGGITQKIGAYQVNWKGQRITFIDTPGHEAFTEMRARGANITDISILIVAADDGVKPQTVEAISHAKEAGVPIIVAINKIDKPGADPMKVRTELTEYGLMSPEWGGTTEFVEISAKQKINLEELLETILITAELQELKANPNKRPKAVVVESRLDPKMGAVADVLVQEGTLKIGDVFVAGESHGRVRSMLDDRGKKISKAIVSQPVEIIGFNVVPNAGDILYGVESDKQAKKIVEDFIRERKVNEQNKKKHISLESLSQELEEQELKELKCIIRADSRGSVEALRESLEKLNTEKVVINVIQGSAGAVTEGDVKLAEASNAIIIAFNVRPTTPARIIAEKTGVEIRNYNVIYHATEEIEKAMKGMLDPEYKEVYYGRIEVKQVFKVSNVGNVAGASVVDGKVTKDSKIRVIRDGIIIFNGELGSLKRFKDDVKEVVTGQECGIGIQDFNDIKAGDIIESYIMEEIPR
>NZ_AP019840.1|WP_146996571.1|1360604_1360973_+|30S-ribosome-binding-factor-RbfA
MNDRRKRGLEKEISRIIGMTLLTDIKNDKIKNLVSIHKVELTKDGRYLDLTFSVLDLKDNINKEKIAEDLNKLKGFFRKKIGSQLSIRFVPEVRIHLDDSVEYGVKIASILNEIKKENDNIE
>NZ_AP019840.1|WP_146996572.1|1361066_1362764_+|single-stranded-DNA-specific-exonuclease-RecJ
MKWELKSYNEDYLTSKSSEFGESRLISRLLLNREINTKEKVSKFLNSDKGDIHNPFLFENMEKVVERIKKAGRNKEKIVIYGDYDVDGISGVAYLVIMLRKLGLNVDYYIPNRVHEGIGINKNLLNFLKKRDAKLFITVDISINNREEILMLKNSGIDIIITDHHRQIGVLEDKEQEKELGILTINPKTSETYPNKSLSGSGVAFKLADAVYERYGVNKKILYDYMDIIMIGTVADVVPMTDENRFIIKKGLNNLKKTKIKGLKYIINYLKINPRNITTSDIGFFIAPIFNALGRIDNSKIVVNFFIQEDDFKLFSIIEEMKRANKIRRYLENEIYNELEEKIQRLERPKYIFMKSRKWHSGVIGVVCSRISIKYNIPVILISIKNGYGKASCRSIEGINIFDILKSVSDKLERFGGHDLAAGFLVSEKYLGEIEKHLRQRLARKNRENVQKTLHVDAWLNIEHLNKRKLHEINRLSPFGLDNQEPNFMDSDINFLNLTRFGINNRHFKGFVRKNNRIISVIGYNLGHKLKTNNFYKKKFKMVYTPIFKSVHSDLFIELKIKDFK
>NZ_AP019840.1|WP_146996574.1|1362821_1364108_+|trigger-factor
MAVKKLNESTYEVSAVREGEELKHLKEHVLVHFKDAKVDGFRPGHVPAKVIEKKFKKDIEGEILNHIISDEYRKAVAENELKPIADIKLEKYELNDDKVEVVFTIPVLPSFELGQYKGVEVEKEKVEITDEKVNEEIEKLRENAAKLKEVAENEEAKNDDVVNINFEGFIDGKAFDGGKAEGYDLTLGSHSFIDTFEDQIAGHKKGDEFDVNVTFPAEYHAESLKGKPALFKVKVNSIKRKEEAELNDDLAKELGFDSVEDMTAKTRENITKREEARAENEFKNKVVDAVVSATEVEVPEALVQREIDYQINRFAQQLQMQGINLNQYFQMTGQTMEAMRESSKENAEKAVKTELVLAEIAKAESIKATDEEVSKEIETLAAMYGLEKDALIADVRKNGNYERFIDETNYRLVNQKTIDLLVNEAKVK
>NZ_AP019840.1|WP_018450081.1|1364418_1364994_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MSVYSPVVIENDGRGERSYDIYSRLLKDRIIFVSGEVEDGMANAIVAQLLFLDAQDNEKDIVMYINSPGGVITAGLAIYDTMRHIKSDVSTVCVGQAASMGAVLLSAGAKGKRYSLPNSRIMIHQPLGGARGQATDIQIQAKEIERMKEITSKILSEATGKSVEEIYADTERDNFMSPEEAVNYGLIDKIL
>NZ_AP019840.1|WP_146996576.1|1365325_1366555_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MANKKKNYCSFCGREEHEVERLIQSPEEDDVFICNECIEDSAELLDSFREYDENEHNREITLLKPKEIKAKLDEYIIGQEQPKKVLSVAVYNHFKRIMHKQKNVDNDVELQKSNVLLVGPTGSGKTLLAQTLAKTLNVPLAIADATTLTEAGYVGDDVENVLLKLIKAADYDIETAEHGIIYIDEIDKIARKSENMSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIEINTKDILFIVGGAFEGLEAKVKDRVNEKRVGFGLETNNTKLDDLTLFENVLPEDLIKFGLIPELIGRLPVITALHGLDEEAMIKILTEPKNSLVKQYKKYFEMENVDLEFDKDAIVEIAQLALKRKIGARGLRSIIESVMTDLMYEIPSKENVKKVIITKEAVTDKEKVIIE
>NZ_AP019840.1|WP_146996577.1|1366622_1368989_+|endopeptidase-La
MQNKPFIATRELVVFPGVVTPIFIGRQSSLKSLEEAISRFDSKLILSAQKDANVEEPKFPEDIYETGVLVHVIQTVKMPNGNVKVLVEAKHRVLINQFPKDDNGVVYAEYEEIFSKPIDESKAEALKRRVIDEFSNYAQKTNKVLPDIIYNIKEISNIDKVFDLICTNLMIAVETKQELLEILDVEARAYKILSILEREIEIFMLEREIENRVKEQMAEVQKNYYLREKIKVMREEMGEGTDSDEELEELDQRVRDAKIPQELKDKLVKELSRMKKMPDFSAESSVIRTYLETVLELPWDVSTNDEIDIEKAEKILNEDHYGLEEVKERILEFLAIKKLNKTLKGSIICLVGPPGVGKTSLAHSVARSMNRKFTRISLGGVRDEAEIRGHRRTYVGAMPGRIINSLKQVGVNNPVMLFDEIDKMASDFRGDPASAMLEVLDPAQNNSFEDHYIDHTFDLSNVFFICTANDLGGIPGPLRDRMEIISIESYTEFEKLNIAKKYLIPQTQEENGLKDYKISFSDKAVMKIINEYTREAGVRNLRREISKLFRKIAKEILVSKSESKKISVSEAKIKKYLGNAKFRVDKVKEKEGKIGVVNGLAWTAVGGTTLEVQAVKMEGKGVLQLTGKLGDVMQESARVAYSYVRHIKNELGIKEKFNETTDVHLHFPEGAVPKDGPSAGITITTAIISVLTDKEVRQDVAMTGEITITGEVLAVGGIKEKVIGAHRVGIRDVVLPYDNKVDTEELPKEIADQMKFYFAKTYDDVKKIVFVEKEAKKSKAVKKVAEKK

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Crispr_ID: NZ_AP019840_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019840_2

1687170-1687578

Unclear

I-B

Consensus_repeat	Method
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	CRISPRCasFinder
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	CRT
GTAAAAGTAGTATATCCATTAAAACAAGGATTGAAAC	PILER-CR

5 spacers

csx1,csx20,cas2,cas4

The CRISPR arrays of NZ_AP019840_2

>merge|NZ_AP019840|2|1687170-1687578|CRISPRCasFinder,CRT,PILER-CR
ATTGCTTGCCTTATTTTAATGGATATACTACTTTTACTCTTTCTATATAGATTTTGATAAACATCCATTAGGGATGGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACAGTTTAAAATGTTTTTTTGCGATTTGATCCGTATGGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACAATAATAGTAGAAGACGAAGACGCTGATTTAGAAGCTGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACCCTATATTATTTTCAGAGAACACTTTCTTCTCAGCTACGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACAAGTATATTTTTTTCTTCTCTCCTATAGTACTTGAAGAGTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC

>NZ_AP019840|2|2|1687170-1687578|CRISPRCasFinder
ATTGCTTGCCTTATTTTAATGGATATACTACTTTTAC	TCTTTCTATATAGATTTTGATAAACATCCATTAGGGATG
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AGTTTAAAATGTTTTTTTGCGATTTGATCCGTATG
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AATAATAGTAGAAGACGAAGACGCTGATTTAGAAGCT
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	CCTATATTATTTTCAGAGAACACTTTCTTCTCAGCTAC
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AAGTATATTTTTTTCTTCTCTCCTATAGTACTTGAAGA
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC

>NZ_AP019840|2|2|1687170-1687578|CRT
ATTGCTTGCCTTATTTTAATGGATATACTACTTTTAC	TCTTTCTATATAGATTTTGATAAACATCCATTAGGGATG
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AGTTTAAAATGTTTTTTTGCGATTTGATCCGTATG
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AATAATAGTAGAAGACGAAGACGCTGATTTAGAAGCT
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	CCTATATTATTTTCAGAGAACACTTTCTTCTCAGCTAC
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AAGTATATTTTTTTCTTCTCTCCTATAGTACTTGAAGA
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC

>NZ_AP019840|2|2|1687246-1687578|PILER-CR
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AGTTTAAAATGTTTTTTTGCGATTTGATCCGTATG
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AATAATAGTAGAAGACGAAGACGCTGATTTAGAAGCT
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	CCTATATTATTTTCAGAGAACACTTTCTTCTCAGCTAC
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	AAGTATATTTTTTTCTTCTCTCCTATAGTACTTGAAGA
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019840.1\|WP_146996972.1\|1689620_1690565_-\|Abi-family-protein	unknown	unknown	gnl\|CDD\|377910
NZ_AP019840.1\|WP_146996964.1\|1679548_1679932_-\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NZ_AP019840.1\|WP_146996967.1\|1683572_1683794_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146996971.1\|1688971_1689265_-\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	unknown	unknown	gnl\|CDD\|379750
NZ_AP019840.1\|WP_146996963.1\|1677411_1677702_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_AP019840.1\|WP_146996974.1\|1691789_1692422_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146996976.1\|1695830_1696070_-\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_AP019840.1\|WP_026749263.1\|1689254_1689545_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NZ_AP019840.1\|WP_146996973.1\|1690740_1691748_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146996975.1\|1692488_1694588_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_AP019840.1\|WP_146996962.1\|1676773_1677397_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NZ_AP019840.1\|WP_172619099.1\|1682044_1683394_-\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|274040
NZ_AP019840.1\|WP_026749267.1\|1695282_1695654_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179603
NZ_AP019840.1\|WP_026749259.1\|1684468_1685161_-\|50S-ribosome-binding-GTPase	unknown	unknown	gnl\|CDD\|226124
NZ_AP019840.1\|WP_146997769.1\|1696436_1699946_+\|methionine-synthase	unknown	unknown	gnl\|CDD\|273959
NZ_AP019840.1\|WP_146996969.1\|1686470_1686653_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146996965.1\|1679952_1681854_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146996970.1\|1687885_1688893_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_AP019840.1\|WP_146996968.1\|1683963_1684194_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223014
NZ_AP019840.1\|WP_036095739.1\|1685317_1685614_-\|4Fe-4S-cluster-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|131546

Protein	Function_ID	Function_description	E-value
NZ_AP019840.1\|WP_146996972.1\|1689620_1690565_-\|Abi-family-protein	gnl\|CDD\|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	1.43187e-33
NZ_AP019840.1\|WP_146996971.1\|1688971_1689265_-\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	1.49946e-32
NZ_AP019840.1\|WP_146996963.1\|1677411_1677702_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.02653e-18
NZ_AP019840.1\|WP_146996976.1\|1695830_1696070_-\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.15695e-13
NZ_AP019840.1\|WP_146996975.1\|1692488_1694588_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_AP019840.1\|WP_146996962.1\|1676773_1677397_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.41148e-17
NZ_AP019840.1\|WP_172619099.1\|1682044_1683394_-\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	2.64385e-30
NZ_AP019840.1\|WP_026749267.1\|1695282_1695654_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179603	PRK03600, nrdI, class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI.	6.23322e-36
NZ_AP019840.1\|WP_026749259.1\|1684468_1685161_-\|50S-ribosome-binding-GTPase	gnl\|CDD\|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	1.59775e-46
NZ_AP019840.1\|WP_146997769.1\|1696436_1699946_+\|methionine-synthase	gnl\|CDD\|273959	TIGR02082, Methionine_synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase. This family represents 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), one of at least three different enzymes able to convert homocysteine to methionine by transferring a methyl group on to the sulfur atom. It is also called the vitamin B12(or cobalamine)-dependent methionine synthase. Other methionine synthases include 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (MetE, EC 2.1.1.14, the cobalamin-independent methionine synthase) and betaine-homocysteine methyltransferase. [Amino acid biosynthesis, Aspartate family].	0
NZ_AP019840.1\|WP_036095739.1\|1685317_1685614_-\|4Fe-4S-cluster-binding-domain-containing-protein	gnl\|CDD\|131546	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme. An iron-sulfur protein with a radical-SAM domain (pfam04055). A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase (formate-pyruvate lyase), is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen radical from the glycine residue. [Energy metabolism, Anaerobic, Protein fate, Protein modification and repair].	4.0521e-21
NZ_AP019840.1\|WP_146996970.1\|1687885_1688893_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_AP019840.1\|WP_146996968.1\|1683963_1684194_-\|hypothetical-protein	gnl\|CDD\|223014	PHA03231, PHA03231, glycoprotein BALF4; Provisional.	2.63476e-07
NZ_AP019840.1\|WP_026749263.1\|1689254_1689545_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	3.06592e-19

>NZ_AP019840.1|WP_146996969.1|1686470_1686653_-|hypothetical-protein
MYPIAESIKKNKKIDSEIYLAKITREQFEKDFFRMFDYVRNVLETDIEEIDLESDLYWEG
>NZ_AP019840.1|WP_036095739.1|1685317_1685614_-|4Fe-4S-cluster-binding-domain-containing-protein
MKVKIASIQRNRYEDGPGIRLTVFFQGCNVKCKGCHNSEIQDIRNGKEYEVKELCEEILSYNLPVKKITVSGGEPLMQEEALEEKENFSDKAIKNFIH
>NZ_AP019840.1|WP_026749259.1|1684468_1685161_-|50S-ribosome-binding-GTPase
MENFKHYRKTDIEKKLEKARFMPLDVMITGVTGAGKSTTLNTIFKKNVATVGNGVDPETIDLEFYSLNDVFRLWDTPGLGDGIKNDEIHKRRLVNLLYKTYSLDGNVYGWVDLAIVVLEGLNRDMGSTYTLLNEVIVPNIQADRILVVINQADMAMKGRHWNKETNKPDETLVEFLEKQASSIQDRVKEATGITIRKPVYYSAEYGYNIEKLLDFIIDNMILERRPLIKA
>NZ_AP019840.1|WP_146996968.1|1683963_1684194_-|hypothetical-protein
MWTDNDDLKDYRKGILEKFVESVAKGAMLGGAIGEILGSFAGLGGIGRIVGSVVGIGLGIAGSLVSGVVDFLGGIF
>NZ_AP019840.1|WP_146996967.1|1683572_1683794_-|hypothetical-protein
MTGIEKVVGTAVVVTAGVVAVAEGINQTVKLMNETVNTADDMFTTMGNMAEDFGNSVNDFCNEVSSFFDSLSW
>NZ_AP019840.1|WP_172619099.1|1682044_1683394_-|TIGR02221-family-CRISPR-associated-protein
MAKILIAGLGKGIKKDGKYRETNYSIEKIDKENIIYKNESFITSALEKHFEIDKTIYIGTVGSMWDNLYSYYCNKYNLKEDEDYTFELLEASSNATQDSEFSEINIKKFNDIFEGKARIILTKFGMNTNEIFENFNLIMEIGNMLNDGDEIYLDITHSFRSNAMWMFLVINYITNVLDKNVEVKMISYGMFEAKYKKEVIENGETKEIEISPVVNLKAFFDLMKWIKGANELKNYGNSYTILEMIDDKDVNKKIRTFSDSLNLNYLGTIKRNLESIKKIMDKIDSIEGPGKLIIPDIVKDFIEIFGNIEKEYEFLFKIAEWNFNQKRYAMVAININEGLREFVAGILEIKDRVSDFNDENSGIFKYFKKIRQSIEYKPNNTKGTFDKKEEKIYKIFEHTRKIRNEIAHSKGEKDTAINDVESLKNYVKDIDTIISDKGFIKYLKLKYNV
>NZ_AP019840.1|WP_146996965.1|1679952_1681854_-|hypothetical-protein
MGNTVTRNELRERVRKILVGTLLNEEEKVSDNLLDTVIKYYFPKQEKNIINGEEKWIPKKQKVIPEEEKFLERGYEDLIKKEREKISGEIDINKVKVIVSAFSLSPKNSLLEEYPFEKDLRIFDNIEKIYLFYTKETEYKFESYKNNCKFNEKIEGVEIDGRTVDETYKKLRELVLKNKINKDNTILDMTLGMKTISIAFYRIAVERQLKAVNWNEKFLSSYTMINENEFVENKNGGTPRIALSAKLSLMKEPIKESARIYSRINDSIRRGNFEAVGNLYEINGNNDMAFFYKELDTIFNADKIIKYNNFEYFYEDVEKLLDIILAKSREFNNMEISKVKKGVAYLANLVWIFSSRKKGKDSKFKLSESDFVENNFSDFRRGEENGIDLEDREEWDDSLEEIMIYLKFKYVILTNKPYFYFERIVNDMKKSQIDDNIQEKIRKYIEESEKESKKISLEKIYKLMFSKKYNFYEEIKKYDMESTLLEILENSLSYKNGILIIPIKSEYNLEAFTLKINFNEEKGLKNILKLRNFEVPIKYEPVHELLREIEIKGYDSTVTSDKIEKIFKKVENPNQSITKFKDVIKNINEVIKEKLKKEAKNENKKIEIKIPDFIEMNNAKKDYSVRISDKWKI
>NZ_AP019840.1|WP_146996964.1|1679548_1679932_-|hypothetical-protein
MEKKVLLVFSHQLTENQEKELIEEYGVKQIESLPEELQNMWSNVSIKKDYKENLEKIKKFVKENFGKKDIILIQGNWGYTYNLVKWSIENGLVPVYSYTERNVEEIKDGENVKKISYFKHVKFIEYE
>NZ_AP019840.1|WP_146996963.1|1677411_1677702_-|CRISPR-associated-endonuclease-Cas2
MMTWFIYDITDDRNRSRLIKIAQKHGLYRVQKSVFLGNIEKDEIDQIIKESRKVIDLKEDSVYIFPVCDADYKKATLLGLAFEKDIVQDEKPVLFF
>NZ_AP019840.1|WP_146996962.1|1676773_1677397_-|CRISPR-associated-protein-Cas4
MDISKNQGISIFQVIDYVYCPRIIYYEEVLKVFGNKMDDFKRKEEKRMEGKGSINRKWIWERLKLRKKDINNLSQWENKEFNKELYSKKYHFYGKIDEILYLQDGTIVPLYYYNSKYTAREDKKYKYLMAMFSMLIEENYKIESQRGYILFLDGLSLKKIEYATKDFEIIKRQIAQILELIKTERYPLEVEGGTKCRDCYYKKICGR
>NZ_AP019840.1|WP_146996970.1|1687885_1688893_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MEKKIYEAVNWNTPENDYVEMFWEQNLKQFWIDTEYIPSKDIDSWNSLEPAMKLAYLHVLGGLTLLDTLQSHTGMPKIIDHIESLQNRSVLSYMCMMETIHAKSYSTIFTTVASTREINETFRWVQENPHLQYKANKIDTYYQKMNNPEASKRDIAMALAASVYLETYLFYSGFFLPLWLAGQGEMVASCDIIKKIIADESIHGVFVGLLFQELYNSFSEEEKADMRAELKNLMYDLYENETRYTDEIYGDLGLTGDVKEYIRYNANKALMNLGFEEEFEVKNVNPIVLNGLNVETTQHDFFSKKSTNYEKALEVVHLHDDDFKFDEEVNADDLI
>NZ_AP019840.1|WP_146996971.1|1688971_1689265_-|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family
MKGKKEEKYSIILTGKFKKHLKNLKKQKKDLKLLESIISILAKGEKLPPKNKDHKLVNNYDGARECRITPDWLLIYEIIEDKLILILLASGSHSELF
>NZ_AP019840.1|WP_026749263.1|1689254_1689545_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MATVNTSIKIDEETKKEAQKLFKDLGLSLSTAINIFLKQAIREKGIPFYINSLPENSELAQAFEEVKQIKKNPSNYKSYSSPEEMFKDVLGEDYEG
>NZ_AP019840.1|WP_146996972.1|1689620_1690565_-|Abi-family-protein
MDKPFKTFKEQVEILNGENGGKLRVKTDDETIYYLMRYNYYSIINFYKEPFLKGKDLNGNDIYKSGVHFNHLKALYDFDKSLRMLFFDVLTQLERAFKTAIAYYYSEYYTNKESYLELDNYYVGVRNENIHLISHLVKKLNFLRNNKSNSIIKHYSTTKDNIPFWIVINFFTFGEMSRFYLILENRVQNKIISHFRNLYKNEYTNLPKLNNNFIKTFLRASSLFRNIVAHNERMYDFSSKNIVNINNIIGITNNKKQKLFTIYEGLKLFLSKEEYESLTKKLRELLSLLEFKLKDIIDINDILYKMDFPKDWHK
>NZ_AP019840.1|WP_146996973.1|1690740_1691748_-|hypothetical-protein
MEELKKNDFEKYIQSFNDIYLNVLTKNLNIIVFILGVIVPLVFSFFSYWSLYKVYKSLGIEYLKNFIELLITILGNKNNLKLILGFFLYIIGVAIYMVVLIYIDYRTICKKIKEYPEIEADKEITKLKKHQIHKKFNKYLKLYCTKKLVQKYEIDKENFRLFLNELITRIDNLKSEKPTVKAIFIIGIYKFFKSKLVILIISYLFGLFGEKLYESNFKILYYIILFYFGIIILFLIYNFFSSKNKNIDIEIERRFILMDILIEIFINSTINETIWITEEAEKKITDNKGYFFTKPREKPVSITEDNDKFFLIEDESNPKNIKLKKIKIEKIKFKQ
>NZ_AP019840.1|WP_146996974.1|1691789_1692422_-|hypothetical-protein
MGDIRFKKLPLLLNDMEKKKWIIDSFPFEYNGVNTIVILRRYTESKKKPNKYAKAEIEFIDENNIEHMICGYIDLYEVYFDNAIKFYNFFRIEGDNNSPRELFLNFSEYFSEFIPKEKIIIKENNTEKEILAKRIDKNDNGIYCFDVRRNGPKKDGSLKKRKPKNSNKAELLRPFLYQKYKGDINLSFYFSPNPEDELSDEEILRKIASR
>NZ_AP019840.1|WP_146996975.1|1692488_1694588_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MVDKRAKKWIYLNNEIMVKKGEDFQLEKDKEAVYSYFVDYVNKNTVFFHNLEEKMRYLIKNDYYIDFYEMYSHDEIKEVFKLVYDKKFRFASFMSASKFYQSYALMDDSGEKFLERYEDRVATVSLYLAQGDVEKAKEYALMLINQEYQPATPTFLNSGKKRSGELVSCFLDEMGDNLSGIGYVFDSSMKLSSIGGGVAINLSKVRARGESIKGVEGRASGVLPIMKILEDIFSYANQLGQRAGAGAVYLNVFHSDINEFLDSKKINVDEKIRIKSLSIGVIVPDKFMQLAMEDEVCYTFNPHTVFLEYGQYLDEMDMNEMYEKLVDNPNVKKKKINARELLVKISQTQKESGYPYLFFKDNANREHALKEIGTVKFSNLCTEIMQLSEVSDINAYYEEDTIRRGISCNLGSLNIATVMENKRIKEATKAAIDSLTMVSDLTNIDIVPSIKKANDELHSVGLGAMNLHGYLAKNFIMYESKEALDFCNVFFMMVNFYSLERSLEIAKEKGETFKDFEKSEYANGNYFDKYITKEYMPQTEKIKQLFEGIYIPTKEDWANLKEQVMKHGVYNAYRMAIAPNQSTSYIMNSTASVMPVVDTIEVREYGDSTTFYPMPYLTNDNYFFYKSAYDMDQKNILKLISVIQRHVDQGISTILYTKSTDSTRDLARLYIYAHRLGLKSLYYTRTRKATIEECISCSV
>NZ_AP019840.1|WP_026749267.1|1695282_1695654_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MYIYYDSKTGNVERFIKKMQVQRPDWHFIKIEPTMTIENEGHFLTFTTKIGEIPATTDEFLQNENNSKLLKSVSSSGNRNWGQFFALAADKIQQKYGIPVLMKFELSGTSTEVENYIDYLENN
>NZ_AP019840.1|WP_146996976.1|1695830_1696070_-|thioredoxin
MKKIIKFEKNDCNPCAMVSDLLDKKGVEYERINPFDNPEMAVKYRVRSVPTVILFEENEEIKRTIGFKPEEINEIISMM
>NZ_AP019840.1|WP_146997769.1|1696436_1699946_+|methionine-synthase
MLTNQYKNSYNLLQNDLKNRILLLDGAMGTMIQQENLTVDDFGGEKYEGCNDYLVLQKPEIIKNIHKRYLEAGSDIIETNSFGALDIVLKDYDLEDKVFEMNKAATELANEAIAEYKNEHPEVTRNLYVAGALGPSNKSISVTGGVTFEELIHTYYTAVSGLLSGGVDLILFETIQDTRNLKAAYLGLKKAMEENYTVPLMLSFTIESTGTTLAGQTADAFYYAVNHMNPFSVGLNCATGPEFMTQFLKTLNNISNTYISVYPNAGLPNEDGEYEETPNTLSAKIEPFFQNNYLNIVGGCCGTTPEHIQKIKEKSANYSPRVIDKNKNFNDVSGLIALETPKDRPIYVGERTNVIGSRIFKNLIASEKFDEATEVARLQIKGRADVIDICLANPDRDEIADMKAFLDKVAKFAKVPLMIDSTDINVVKEGLTYLQGKGIINSINLEDGEKKFADMAKVIKDFGASVVVGLIDEEGMAVSVEKKLKVARRSYELLTKKYGIDERDIIFDTLVFPVATGDQKYIGSATATIEAIRQIKAEMPNVKTILGVSNVSFGLPIAGREVLNTYYMQKAYEAGLDYAIVNTEKVMPMSEISDEEKELSENILFHTDDENVSKFANFYREKKAVQKVVDTSNLTTEEKVSNLVVEGSKKDLTMHLDELLKKYSPIDIINGPLMTGMDEVGRLFNNNDLIVAEVLQSAEVMKASVSHLEQFMEKDESSVKGKVIMATVKGDVHDIGKNLVGIIIGNNGYEVIDLGINTPAEKIREAIIEHKADFLGLSGLLVKSATEMVNTMEVLHEAGIDIPIFVGGAALTEKFTVNKIEPAYKNNIVIYSRDAMTALADLNKMINEKKFEEFKEYLQKRRDLVTIKDAKKLEQLKVKPTVSDIKDADGTFDFSKVELPKYNFEKIYKPETLNKQIITNIKAKDVFPFVNLQMLIGKHLGMKWIVNNLIEKQDPRTIKLYNEILDIIENGDEYFDIKAIYKFFPVRRKVGERKDDFKIEVLSDDLSTVLETFDFPRQKYGQYLSLNDYVNPDRIDYIGFFVATAGEKSRLVSNELKEKGEFYRGHIVNSIGLELAEATSEYIHKMMRQDVGIIDKDITLNEILNAQYQGNRYSFGYPACPDLSDQRKLFNLLKPERYGISLTEEFMMYPEATVSAIVFSQPFCKYFNM

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Crispr_ID: NZ_AP019840_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019840_3

2639234-2639338

Orphan

Consensus_repeat	Method
TGGTTCTCTTTTCACATATACAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019840_3

>merge|NZ_AP019840|3|2639234-2639338|CRISPRCasFinder
TGGTTCTCTTTTCACATATACAACTTTTTTTCTTCTTGGAACTCTTATAAAGATGTATCTTCTTCTTATTACTCTTCTTCTTGGTTCTCTTTTTACATATACAAC

>NZ_AP019840|3|3|2639234-2639338|CRISPRCasFinder
TGGTTCTCTTTTCACATATACAAC	TTTTTTTCTTCTTGGAACTCTTATAAAGATGTATCTTCTTCTTATTACTCTTCTTCT
TGGTTCTCTTTTTACATATACAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019840.1\|WP_146997570.1\|2631534_2632353_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_AP019840.1\|WP_026749444.1\|2649964_2650612_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|236773
NZ_AP019840.1\|WP_146997576.1\|2638126_2638786_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_AP019840.1\|WP_146997572.1\|2634581_2635364_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_172619138.1\|2636649_2637411_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_AP019840.1\|WP_026749440.1\|2646756_2647164_+\|adhesion-protein-FadA	unknown	unknown	gnl\|CDD\|370466
NZ_AP019840.1\|WP_146997580.1\|2647244_2647658_+\|adhesion-protein-FadA	unknown	unknown	gnl\|CDD\|370466
NZ_AP019840.1\|WP_146997581.1\|2647986_2648877_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_AP019840.1\|WP_146997578.1\|2642464_2644120_+\|5'-nucleotidase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|223808
NZ_AP019840.1\|WP_146997571.1\|2633051_2634581_+\|dynamin-family-protein	unknown	unknown	gnl\|CDD\|366045
NZ_AP019840.1\|WP_146997579.1\|2645282_2646593_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_AP019840.1\|WP_051354473.1\|2644330_2645056_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146997582.1\|2648976_2649765_+\|META-domain-containing-protein	unknown	unknown	gnl\|CDD\|377111
NZ_AP019840.1\|WP_146997577.1\|2639736_2641527_+\|NAD-nucleotidase	unknown	unknown	gnl\|CDD\|211667
NZ_AP019840.1\|WP_146997575.1\|2637468_2638146_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_AP019840.1\|WP_026749431.1\|2635743_2636592_-\|cysteine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270412
NZ_AP019840.1\|WP_146997569.1\|2630594_2631455_-\|GyrI-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|226231
NZ_AP019840.1\|WP_146997786.1\|2641978_2642347_+\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212143
NZ_AP019840.1\|WP_146997573.1\|2635441_2635660_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019840.1\|WP_146997568.1\|2628693_2629647_+\|ATPase	unknown	unknown	gnl\|CDD\|379051

Protein	Function_ID	Function_description	E-value
NZ_AP019840.1\|WP_146997570.1\|2631534_2632353_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.34443e-66
NZ_AP019840.1\|WP_026749444.1\|2649964_2650612_+\|C40-family-peptidase	gnl\|CDD\|236773	PRK10838, spr, bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase.	5.84076e-34
NZ_AP019840.1\|WP_146997576.1\|2638126_2638786_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.00868e-56
NZ_AP019840.1\|WP_172619138.1\|2636649_2637411_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.08121e-136
NZ_AP019840.1\|WP_026749440.1\|2646756_2647164_+\|adhesion-protein-FadA	gnl\|CDD\|370466	pfam09403, FadA, Adhesion protein FadA. FadA (Fusobacterium adhesin A) is an adhesin which forms two alpha helices.	5.22541e-21
NZ_AP019840.1\|WP_146997580.1\|2647244_2647658_+\|adhesion-protein-FadA	gnl\|CDD\|370466	pfam09403, FadA, Adhesion protein FadA. FadA (Fusobacterium adhesin A) is an adhesin which forms two alpha helices.	9.6024e-25
NZ_AP019840.1\|WP_146997578.1\|2642464_2644120_+\|5'-nucleotidase-C-terminal-domain-containing-protein	gnl\|CDD\|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	3.57435e-89
NZ_AP019840.1\|WP_146997571.1\|2633051_2634581_+\|dynamin-family-protein	gnl\|CDD\|366045	pfam00350, Dynamin_N, Dynamin family.	1.531e-13
NZ_AP019840.1\|WP_146997579.1\|2645282_2646593_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_AP019840.1\|WP_146997581.1\|2647986_2648877_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.75112e-20
NZ_AP019840.1\|WP_146997582.1\|2648976_2649765_+\|META-domain-containing-protein	gnl\|CDD\|377111	pfam03724, META, META domain. Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.	6.24595e-22
NZ_AP019840.1\|WP_146997575.1\|2637468_2638146_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.04497e-59
NZ_AP019840.1\|WP_026749431.1\|2635743_2636592_-\|cysteine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270412	cd13694, PBP2_Cysteine, Substrate binding domain of ABC cysteine transporter; the type 2 periplasmic binding protein fold. This subfamily comprises of the periplasmic-binding protein component of ABC transporter specific for cysteine and its closely related proteins. The cysteine-binding domains belong to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.30303e-123
NZ_AP019840.1\|WP_146997569.1\|2630594_2631455_-\|GyrI-like-domain-containing-protein	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	7.47839e-32
NZ_AP019840.1\|WP_146997568.1\|2628693_2629647_+\|ATPase	gnl\|CDD\|379051	pfam13177, DNA_pol3_delta2, DNA polymerase III, delta subunit. DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.	1.51479e-36
NZ_AP019840.1\|WP_146997577.1\|2639736_2641527_+\|NAD-nucleotidase	gnl\|CDD\|211667	TIGR01530, Probable_5'-nucleotidase, NAD pyrophosphatase/5'-nucleotidase NadN. This model describes NadN of Haemophilus influenzae and a small number of close homologs in pathogenic, Gram-negative bacteria. NadN is a periplasmic enzyme that cleaves NAD (nicotinamide adenine dinucleotide) to NMN (nicotinamide mononucleotide) and AMP. The NMN must be converted by a 5'-nucleotidase to nicotinamide riboside for import. NadN belongs a large family of 5'-nucleotidases and has NMN 5'-nucleotidase activity for NMN, AMP, etc. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	0
NZ_AP019840.1\|WP_146997786.1\|2641978_2642347_+\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212143	cd11536, NTP-PPase_iMazG, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in integron-associated MazG (iMazG) proteins. This family corresponds to the iMazG proteins representing a new subfamily of MazG NTP-PPases. iMazG is likely to act as a house-cleaning enzyme capable of removing aberrant dNTPs, preventing the incorporation of damaging non-canonical nucleotides into host-cell DNA. It can convert dNTP to dNMP and pyrophosphate by cleaving between the alpha- and beta-phosphates of its dNTP substrates, with a marked preference for dCTP and dATP. Unlike typical tandem-domain MazG proteins, iMazG contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. The divalent ions, such as Mg2+, are required for its pyrophosphatase activity.	7.04044e-31

>NZ_AP019840.1|WP_146997576.1|2638126_2638786_-|ABC-transporter-permease-subunit
MDFNFIIENISKYLEAMKLTVLIGIFGIVFSILIGIVCALVLYYRVPVARQIVEIYIELSRNTPLVIQLFFLYFGLPKIGITFNSHACAVIGLSFLGGSYMCEAFRSGLESITKGQRESGLSIGLTEFQLVTNVILPQAFTVSFPAIGANVIFLLKETSVIGILALMELMYLTRDLIGLYYKTNESLFMLVVAYLIIILPVSIILAVIERRVRYATVGN
>NZ_AP019840.1|WP_146997575.1|2637468_2638146_-|ABC-transporter-permease-subunit
MQLSGIDVIFKGVNLQRLMGGLAVTGQVALVSIVFSILFGIILGIVMTSKNKIIYGILKFYLESMRIIPLLVWLFIIYFGVAKGFGLHIDSKTTTIIVFVIWGTAEMMDIVRGAIISLPKIQGESAKALGLDTSQVYRYVLLPQAVRRIAPAAVNLITRMIKTTSLAIFIEVAEVLKIGRQIIEFSSRKNPMAPFWVYLFIFFLYFIVCYPITMLSKKLEKKWVV
>NZ_AP019840.1|WP_172619138.1|2636649_2637411_-|amino-acid-ABC-transporter-ATP-binding-protein
MELSDIKKEYKKGVPALKGVSLSVNKSEVVVILGPSGCGKSTLLRCVNGLEEIQSGEIKLQGNIINKDKTKWHLIRQRIGMVFQSYELFDHMTVMQNLLLGPLKVQKRDKNEVTEQAEKLLERVGLLDKKNSYPRELSGGQKQRIAIIRSLCMNPEIMLFDEVTAALDPEMVREVLDVMLELAKEGMTMIIVTHEMEFAKAVADRIVFMDSGEVVETNYPLEFFRNPKTERAKKFLNIFNFEKKDKVESALLI
>NZ_AP019840.1|WP_026749431.1|2635743_2636592_-|cysteine-ABC-transporter-substrate-binding-protein
MKKNFERFVKIIAILVLGVFAISCGKGEKGSAKPGSIEAIKKAGKIRIGVFGDKPPFGFVDENGKNQGYDIYLAKRLAKDLLGDENKIEFVTMEAANRVEYLLSNKVDITLANFTVTDERKEKVDFAKPYMKVSLGIVSPEGAPIKDVKELKGKKLIVNKGTTAEIYFTKNHPDIELLKYDQNTETFNALLDKRGAALAHDNTLVFAWATENPGFVVDIKELGEQDYIAPAVRKGNKELLDWLNAEIDALTKEGFFEKAYKATLEPVYGNKVDPKTVIIEKK
>NZ_AP019840.1|WP_146997573.1|2635441_2635660_+|hypothetical-protein
MRLDKIILEQEIINQRIDMLQEIINVSNEKLMNYQTKESQNMYGILNQLLLKDVLENYDGTLQELIKKHNSK
>NZ_AP019840.1|WP_146997572.1|2634581_2635364_+|hypothetical-protein
MGIWNLIENAIEGAADFVRNTGIIDKIVEIGEGIADWFKDVFNIGDAPSYDKDTATIDETKKVNEILQTYIEKCLNISEKYDNISKEEINKYFSQIKNSLTDINKISENNTENSDKVIEDYIFDSLELNRNTTLKSLDKIYSNEIKDAYSLSNFELLDILKMEQGREKKKKMNAFSVKTLTEANEFLFDELKNSINQQQNLVDKKLRDYMYSREEETRRSIEKINEILDSVKTGEKEKQELKNSYVELLDEVKLFDEIFA
>NZ_AP019840.1|WP_146997571.1|2633051_2634581_+|dynamin-family-protein
MLNLEQYIRNNNEELINIHWNETINEYVKKLNASKVLFKNLSEKEYFKSTDTLKGNTFFKEINTEISRYISDSKNPSYQIAIVGAVKAGKSTLINALIGYDLASTNVTPETATLTKIKTTDKNSITVKFYSREEWKKIWNDAQKSTNATIFKEEFDNLRAKEIESEMLGKSDIFKEFDNLDSMKDEIKKWTSSHAREHYFVKEIEIGVEKLNLPPQVCLVDTPGLNDPVQYRSNITSEYIHSANAVIICVNAKTLRNEEIATILDVLTKAQDKKDKVYILGTQIDIMNSQADWEQQQEEWLKHLKEKQFYGSLDMAKEQLIGVSSYFYSNAIKLSSDTDIDSLEDSIDDLVKKEKMTKQDRRELLRKDNITPEDIEQIKNMLIDYSNIEIVNDNIQNKLILGFNESLKNDFLNRYNYLKNKIETFKKEHIEKIQGNINSFEQSENELKQQILQNERQKEELETLNRRLRLKIRETTQAFNTDFEELNSNFRNLMREIKKVKFEEESEDK
>NZ_AP019840.1|WP_146997570.1|2631534_2632353_-|Cof-type-HAD-IIB-family-hydrolase
MNYKLIATDMDGTLLDEEHGITSENVEAIVKVQKEKGVKFVLASGRPSYAMFEYAKELQMDKYEGYVLAFNGGELIDMKTNEVIFHEGLGKKDIENVYKVSKEINVPMILYVGDTIYGTEATDGVMYETNQCKMKFQKFDSLEDLEKKGIDKTTKCMIIGTPEEVLMAEEHMNKVHGNDYFIAISKPIFLEIANKNVDKGKTLKKLGEIENIKPEEMIAVGDSANDKPLLEYVGMPVAVENAIPEIKSISKFISTSNVKHGLKTTIEEFFEF
>NZ_AP019840.1|WP_146997569.1|2630594_2631455_-|GyrI-like-domain-containing-protein
MIKAFNETMKYIEDTLTDRIDERKIALLSGYSYPLFSRMFSIMVDYPLSEYIRFRKLSCAAIDLRESDEKIIEIAFKYGYESQDSFSLAFKKFHGHTPKEVRKGSAFQIFSPIRLSLSIEGGKNMDIKVMKKSAFKIAGLVERIEEGGDFPNVWDKLFKKVSPEKLENLGNRQSYGACYEIEKNENCESKFTVNYMAGYDIQNVTEANDLGLNILEVPEAEYAVVKLKGIVPNCIHEGWKYVTGTFFPEQGYRHAGTPDFEVYSEGDMYSPDYEMELWVPIVKDKN
>NZ_AP019840.1|WP_146997568.1|2628693_2629647_+|ATPase
MKLQEITEKFNNEINQDKISASYLFYGDKRVDLLSYALMFSKMIMTKDVQNDSEKEKIERLINNFQHPDIEIINKSNENIKINEVREIIYSSIESSFNSPKKIFILCGIENLRKESSNALLKILEEPPQNVYFILLSRTLNIISTIKSRTIKFHLSGMNNDELGVSKEIYYFFDGNENDILEFKRQNLSLDDIEFKINTVEDILQIIFEMKNYTTGELVIKNNLDLTIKYNKSIELLACRIRFWDIENVYFFINEIENELKKEKEFLISFLSKIIINVKHSVEAYELKKLINLKNSIRSNVNVKSVIFNFFDILQNS
>NZ_AP019840.1|WP_146997577.1|2639736_2641527_+|NAD-nucleotidase
MKKLLLLGLTLALFSTVNLEAKTNRKVNKQDSSDSFELNVAHINDHHSHLEEEKMPLKLNGKTVTVHIGGLPRVAQEIKNFRQNNKNTLVLHAGDAVTGTLYYTLFEGKADAELMNAINFDVYTLGNHEFDDGNKFLKAFLDVLKIPVVSANVVPDKGSILEGKWKPYIIKNIGGQKVGIIGLDVVKKTKESSSPGDDIKFFDEIETARKYVNELQSKGINKIILLSHAGYEKNVEIGQKVDGVDLIITGDTHYLLGKEFEQFGLVPEADSYPKKVNSPNGNPVYIAEAWNYSYLLGQMKAKFDKNGVITELTPTPKVLISDDFFEIKNAEGKAVQLNQKEKNEILNSIKNNKNIAAIKNDPALAKLLERYQKEKTELGKRTVGKITEEIPGGSDNRVPNEHNKDGSFATTLVAESVLHKLRNTGTGNVNFVIGNAGNVRITLNPGVFTYDLAYSLLPFTSNTVFITDITGAEVKQTLEDAIDYVLNGGSTGAFPYGAGIRYEATKEGKLGTRVKKIEVFDFKANKWVPIDAKKSYMLAVNSYIAKGKDGYTTLGKITAQKRGTDTHLSDTKIFIDYLKEKKEIGKPKSTNVIFKY
>NZ_AP019840.1|WP_146997786.1|2641978_2642347_+|nucleotide-pyrophosphohydrolase
MTLKEVQYLIKRIEKGTLDETKDDKSPQQKRENGQRLILKLIEEFGELAENIRKNVRYDGKNIKGTIEEEVFDVFYYIIAIANDYEIDLEKIFYIKDEVNEVKYDRDFSIYEARNKWKSMKK
>NZ_AP019840.1|WP_146997578.1|2642464_2644120_+|5'-nucleotidase-C-terminal-domain-containing-protein
MTAKNTNTSFKKKEVSIKILGTSDVHGRVLAWNYAADEEDKSGSYAQISTLVKKIRKKNKNVILVEVGDAIQDNWIEKFAMTPKHPIPEILNYMGYDIFVPGNHEFNFGMPTLSNILRDMKFKKLTANLYYNENAENDTNFSKDKSRYLDATTIIEKDGVKIGIIGLSTPMSAQFEEDTGYLNDFYFVSPVKETQRQIKKLKEEGANAIVVVAHMGIENENGIPETGVKDLANAVPEIDVIVAGHMHQNIPKEIINGVLITEPHRYGTVISEVDLKFEVIGENIKLISKDSTTIPVKNEKSDKKIEEIYKPFHRRLCTIANEEIGETLNDMIPKEKHHGVSAAFGKDTGMSSFITDVELYYSGADVVSFAYNYENVKLDKGKIRRKDIVYNYRYTGGDVTIYEMTGKQLKDYMEWAADYFDTIQAGDTEYRYNPERANGKYVTFDIFGGVKYKIDLRNEKGSKITNLMLKNGTKITPNMKLKVGMNAYRFEQLARKGGIFDGQEIPVLWASKEAIGNIKGTIQNMMIDYIRNVKNGVIEGKSHNNWEIIGL
>NZ_AP019840.1|WP_051354473.1|2644330_2645056_+|hypothetical-protein
MSFGNDETVIGEKLNKLLAILKKDERNYIVSEDIITIYESKIGKDYEKYLDLFTKYTPYDYEKLFAKMVYYRGTGKKDKSDNYYKEIERKYSNTPIMEIIKIYNTANENDRQVQTKKVLNLLKSEEVKRQVGMTDEEVHSMNLTYTLAQVRKYYNNGEIEKSVSEYINNVANASVSNEVRDYNRRKETLLLLNALMVNEEITNKKLREQNKQKLENTYISKEIKKATVKDANYLDKYLNEM
>NZ_AP019840.1|WP_146997579.1|2645282_2646593_+|phosphopyruvate-hydratase
MTRIEDIYAREILDSRGNPTVEVEVYLEGGAMGRASVPSGASTGVHEAVELRDGDKSRYLGQGVLQAVENVNKVIAEHLIGFDALDQVAIDKAMIELDGTPNKGKLGANAILGVSLAVAKAAANQLGIPLYRYLGGVNAKELPVPMMNILNGGSHADSAVDVQEFMVQPVGAKTYKEALRMGSEIFHHLGKILKANGDSTNVGNEGGYAPSNINGTEGALDVISQAVEAAGYKLGDDITFAMDAASSEFATKNADGSYTYTFKREGGVVRNSDEMVEWYKHLTSKYPIVSIEDGLAEDDWDGFKKLTDAIGKDVQLVGDDLFVTNTQRLADGIEKGIANSILIKVNQIGTLTETLDAIEMAKKAGYTAVVSHRSGETEDDTIADIAVATNAGQIKTGSASRTDRMAKYNQLLRIEDDLAEEAVYEGKKAFYNINIK
>NZ_AP019840.1|WP_026749440.1|2646756_2647164_+|adhesion-protein-FadA
MKKVGILFVLLSALSFSAASSKSSKTTTNQTVTGRFNQLEAEYERLVNMENQEYSKLKANAEAASNKLAEKEAQKAQIEERIAKIEAAADSKAFKAQYSELAKQYKAVVKALDSEIKSLSTTVENFAAIEALKGN
>NZ_AP019840.1|WP_146997580.1|2647244_2647658_+|adhesion-protein-FadA
MKKKLAVLLGVLVLSSVSFAAPKAKAAAKPATGGSIESSLSNLENQLVKLQQMEDAKFREQEAQANAAAQRLSNYTAMQAKIDERIAEIEANVDTSIFRKEFKAKVTEYKNLRNQLDKEIAKEQQVLDNFELIKSLR
>NZ_AP019840.1|WP_146997581.1|2647986_2648877_+|EamA-family-transporter
MQTQKKLHGMLLASLASSLWAISGISGEILFKKFNFSSDWLVSTRTLISGILLFAIVISIEKKSVLKPLKNKKDCLGIILFGTAGMYLVQYTYFKTIELSNVSFATILQFTAPFFIFVYESAKNRKLPSVSTIILLFMTILGVVFIATKGNFSNLSISMEALVFGLVSAIMIAFYSTYPKKLLKKYGSITVVGWGMIVGSIISNIIHPIWKIEGNVNAKSIIQVIIVVILGTSIAYLIYIASLNYISSSLAGILTAFEPVLAAILSVIIFGLKFSSVEIVGFVLVFVSIFILEKRL
>NZ_AP019840.1|WP_146997582.1|2648976_2649765_+|META-domain-containing-protein
MKKIFVLIGIFAMFVVNCFILSAAQTVNLNGTSWQLSRIRQNGVNLEIPRNTKITVSFSGNKISGFSGINRYNGTYRVRNNSTLSTDISTTLMGGSEELMNFEMAFLDILQSSPKINYNKGTLTLRNSNGDTLSFNKSSNSNNQSDENSLSRLTKELSGTDWKLVNMNGKEVRNAGITISFSGNKINGNSGINSYFSDYIITAGNITIGTVGSTEMAGSDSLMKTERQYIELLQNAKKIELVNKTTLVLTTNRGKTLTFEKL
>NZ_AP019840.1|WP_026749444.1|2649964_2650612_+|C40-family-peptidase
MRKNKFLTAICMLSAFVGSNLHAKTSKTKKVSKPKTSHKPVNNKKSHSGSNTGIYGISSNNKNALIETKMTELRQRHAKAMASGSAQERRKAAVERKLLTSYSKWRGTKYAWGGDSKKGIDCSALTRRVYREAFNKELPRVSQQQIKKGTRVSAKNLKSGDIVYFTPENRTSHTAVYVGNSLFINASSSKGVVMSSLKSPYWRKYFKYGVRAHNT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1529620 : 1612952

Bacillus_phage(19.23%)

protease,tail,portal,tRNA,terminase,plate,integrase,capsid

attL 1604376:1604391|attR 1611230:1611245

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146996789.1\|1529620_1530730_-\|integrase	tyrosine-type recombinase/integrase	Q8SBN2	Clostridium_phage	1.6e-60	37.6
WP_146996791.1\|1531058_1531523_-	hypothetical protein	NA	NA	NA	NA
WP_146996793.1\|1531649_1534922_-	DUF3427 domain-containing protein	Q8W5V9	Listeria_phage	3.1e-24	26.1
WP_146996795.1\|1534977_1535616_-	3'-5' exonuclease	NA	NA	NA	NA
WP_146996797.1\|1535658_1537455_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	2.1e-22	25.2
WP_146996799.1\|1537797_1538439_-	YdcF family protein	NA	NA	NA	NA
WP_146996801.1\|1538555_1539467_-	major facilitator superfamily domain-containing protein 7	NA	NA	NA	NA
WP_026747354.1\|1539489_1539774_-	endoribonuclease VapD	NA	NA	NA	NA
WP_146996803.1\|1539862_1540933_+	hypothetical protein	NA	NA	NA	NA
WP_146996805.1\|1541401_1543297_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.0e-40	26.1
WP_146996807.1\|1543296_1545036_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	4.0e-39	26.8
WP_026747350.1\|1545199_1545937_-	esterase family protein	NA	NA	NA	NA
WP_146996809.1\|1545964_1547170_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_146996811.1\|1548280_1548502_-	hypothetical protein	NA	NA	NA	NA
WP_026747347.1\|1548501_1549092_-	imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_146996813.1\|1549241_1549613_+	hypothetical protein	NA	NA	NA	NA
WP_146996815.1\|1549676_1550756_-	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_146996817.1\|1550784_1551450_-	hypothetical protein	NA	NA	NA	NA
WP_146996819.1\|1551486_1552680_-	AAA family ATPase	NA	NA	NA	NA
WP_146996821.1\|1552923_1554204_-	histidinol dehydrogenase	NA	NA	NA	NA
WP_146996823.1\|1554333_1554951_-	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_146996826.1\|1554947_1556087_-	ATP phosphoribosyltransferase regulatory subunit	NA	NA	NA	NA
WP_146996827.1\|1556200_1556836_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_172619088.1\|1556943_1557480_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_146996832.1\|1557620_1558703_-	dihydropteroate synthase	NA	NA	NA	NA
WP_146996834.1\|1558874_1560266_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_146997765.1\|1560333_1560882_-	DUF1851 domain-containing protein	NA	NA	NA	NA
WP_146996836.1\|1560924_1561176_-	hypothetical protein	NA	NA	NA	NA
WP_146996838.1\|1561150_1561330_-	hypothetical protein	NA	NA	NA	NA
WP_146996840.1\|1561410_1562877_-	hypothetical protein	NA	NA	NA	NA
WP_146996842.1\|1562912_1563503_-	GTP cyclohydrolase I FolE	A0A088F7Y4	Vibrio_phage	4.9e-37	45.2
WP_146996845.1\|1564122_1564611_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_026747330.1\|1564638_1564989_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_172619131.1\|1565113_1566010_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	3.1e-75	52.0
WP_026747328.1\|1566149_1566695_-	hypothetical protein	NA	NA	NA	NA
WP_026747327.1\|1566874_1567387_-	PH domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	7.4e-34	47.4
WP_146996849.1\|1567749_1568427_+	helix-turn-helix domain-containing protein	A0A0E3U270	Fusobacterium_phage	6.9e-19	34.5
WP_026747326.1\|1568465_1568810_+	hypothetical protein	NA	NA	NA	NA
WP_036094820.1\|1569022_1569424_+	large-conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_146996853.1\|1571700_1576680_-	autotransporter-associated N-terminal domain-containing protein	NA	NA	NA	NA
WP_146996855.1\|1577299_1578289_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_146996857.1\|1578388_1579183_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_146997766.1\|1579387_1579711_-	hypothetical protein	NA	NA	NA	NA
WP_146996859.1\|1579688_1580060_-	hypothetical protein	NA	NA	NA	NA
WP_172619089.1\|1580078_1580219_-	hypothetical protein	NA	NA	NA	NA
WP_146996861.1\|1580305_1580698_-	hypothetical protein	NA	NA	NA	NA
WP_146996863.1\|1580699_1581281_-	N-acetylmuramoyl-L-alanine amidase	G9J3I1	Clostridium_phage	9.7e-06	30.8
WP_146996864.1\|1581282_1581819_-	hypothetical protein	A0A0E3JI96	Rhodoferax_phage	9.0e-14	37.1
WP_146996865.1\|1582087_1582651_-	hypothetical protein	NA	NA	NA	NA
WP_146996866.1\|1582800_1583778_-\|tail	phage tail protein	NA	NA	NA	NA
WP_146996867.1\|1583782_1584427_-\|tail	phage tail protein I	A0A0C5AJ63	Bacteriophage	2.2e-19	31.1
WP_146996868.1\|1584423_1585536_-\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	2.3e-56	36.7
WP_146996869.1\|1585528_1585843_-	hypothetical protein	NA	NA	NA	NA
WP_146996870.1\|1585842_1586634_-\|tail	phage tail protein	NA	NA	NA	NA
WP_146996871.1\|1586633_1587083_-\|plate	phage baseplate protein	NA	NA	NA	NA
WP_146996872.1\|1587292_1587787_-	hypothetical protein	NA	NA	NA	NA
WP_146996873.1\|1587796_1588651_-	hypothetical protein	A0A0C5AJ59	Bacteriophage	4.0e-24	29.9
WP_146996874.1\|1588653_1588875_-\|tail	tail protein X	A0A2K9V2S8	Faecalibacterium_phage	2.2e-06	40.3
WP_146996875.1\|1588874_1591907_-\|tail	phage tail tape measure protein	Q8W620	Enterobacteria_phage	1.6e-43	28.7
WP_071124839.1\|1591986_1592208_+	hypothetical protein	NA	NA	NA	NA
WP_146996876.1\|1592406_1592775_-	hypothetical protein	NA	NA	NA	NA
WP_146996877.1\|1592794_1593322_-\|tail	phage major tail tube protein	NA	NA	NA	NA
WP_146996878.1\|1593333_1594782_-\|tail	phage tail sheath protein	A0A0E3U251	Fusobacterium_phage	3.7e-54	32.1
WP_146996879.1\|1594771_1595014_-	hypothetical protein	NA	NA	NA	NA
WP_146996880.1\|1595022_1595496_-	hypothetical protein	NA	NA	NA	NA
WP_146996881.1\|1595495_1596038_-	hypothetical protein	NA	NA	NA	NA
WP_146996882.1\|1596038_1596368_-	hypothetical protein	NA	NA	NA	NA
WP_146996883.1\|1596378_1596609_-	GTP-binding protein LepA	NA	NA	NA	NA
WP_146996884.1\|1596618_1597632_-\|capsid	major capsid protein	NA	NA	NA	NA
WP_146996885.1\|1597631_1597967_-	hypothetical protein	NA	NA	NA	NA
WP_146996886.1\|1597966_1599112_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A067ZG37	Vibrio_phage	4.8e-57	39.8
WP_146996887.1\|1599071_1600625_-\|portal	phage portal protein	A0A0C5AJ48	Bacteriophage	1.2e-135	48.6
WP_146996888.1\|1600643_1600874_-	hypothetical protein	NA	NA	NA	NA
WP_146996889.1\|1600877_1602686_-\|terminase	phage terminase large subunit family protein	A0A2K9V3X4	Faecalibacterium_phage	1.0e-154	45.9
WP_146996890.1\|1603357_1603690_-	hypothetical protein	NA	NA	NA	NA
WP_021744358.1\|1603756_1603954_-	hypothetical protein	NA	NA	NA	NA
WP_146996891.1\|1603973_1604339_-	hypothetical protein	NA	NA	NA	NA
1604376:1604391	attL	NA	NA	NA	NA
WP_146996892.1\|1604739_1605408_-	hypothetical protein	NA	NA	NA	NA
WP_172619090.1\|1605476_1605647_-	hypothetical protein	NA	NA	NA	NA
WP_146996893.1\|1605661_1605898_-	hypothetical protein	NA	NA	NA	NA
WP_146996894.1\|1605922_1606168_-	hypothetical protein	NA	NA	NA	NA
WP_146996895.1\|1606189_1606495_-	hypothetical protein	A0A067XQV6	Caulobacter_phage	6.9e-11	55.1
WP_172619091.1\|1606508_1606676_-	hypothetical protein	NA	NA	NA	NA
WP_158663011.1\|1606650_1606821_-	hypothetical protein	NA	NA	NA	NA
WP_071124815.1\|1606837_1607254_-	hypothetical protein	A0A0A7RUP7	Clostridium_phage	7.7e-13	39.4
WP_162840183.1\|1607255_1607420_-	hypothetical protein	NA	NA	NA	NA
WP_146996896.1\|1607428_1607635_-	hypothetical protein	NA	NA	NA	NA
WP_071124813.1\|1607591_1607957_-	single-stranded DNA-binding protein	A0A218KCM4	Bacillus_phage	1.7e-16	43.9
WP_071124812.1\|1607960_1608167_-	hypothetical protein	NA	NA	NA	NA
WP_071124811.1\|1608185_1609214_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	4.7e-19	25.4
WP_146996897.1\|1609226_1609931_-	N-6 DNA methylase	NA	NA	NA	NA
WP_071124809.1\|1609955_1610717_-	hypothetical protein	D7RWH3	Brochothrix_phage	4.7e-16	30.5
WP_146996898.1\|1610716_1611235_-	hypothetical protein	NA	NA	NA	NA
WP_146996899.1\|1611237_1611870_-	hypothetical protein	NA	NA	NA	NA
1611230:1611245	attR	NA	NA	NA	NA
WP_146996900.1\|1611866_1612952_-	hypothetical protein	A0A0S2SXI2	Bacillus_phage	9.6e-39	55.4

DBSCAN-SWA_2

2537473 : 2545240

uncultured_Caudovirales_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146997497.1\|2537473_2539039_-	ParB N-terminal domain-containing protein	A0A2H4J2F5	uncultured_Caudovirales_phage	1.3e-97	48.1
WP_026748714.1\|2539135_2539330_-	hypothetical protein	NA	NA	NA	NA
WP_146997498.1\|2539375_2539675_-	hypothetical protein	NA	NA	NA	NA
WP_026748716.1\|2539692_2539914_-	hypothetical protein	NA	NA	NA	NA
WP_146997499.1\|2540128_2540359_-	hypothetical protein	NA	NA	NA	NA
WP_146997500.1\|2540355_2541075_-	hypothetical protein	A0A0E3Y6J2	Fusobacterium_phage	1.4e-17	35.0
WP_146997501.1\|2541041_2541224_-	hypothetical protein	NA	NA	NA	NA
WP_146997502.1\|2541225_2541840_-	Rha family transcriptional regulator	A0A288WFT2	Bacillus_phage	5.3e-18	33.6
WP_146997503.1\|2541839_2542337_-	dUTP diphosphatase	NA	NA	NA	NA
WP_146997504.1\|2542337_2542694_-	RusA family crossover junction endodeoxyribonuclease	G7YZ89	Streptococcus_phage	5.0e-05	31.8
WP_146997505.1\|2542697_2543075_-	hypothetical protein	NA	NA	NA	NA
WP_172619116.1\|2543108_2543531_-	class I SAM-dependent methyltransferase	A0A059T693	Listeria_phage	1.7e-55	68.3
WP_146997507.1\|2543775_2544537_-	ATP-binding protein	NA	NA	NA	NA
WP_146997508.1\|2544448_2545240_-	helix-turn-helix domain-containing protein	A0A1V0E018	Clostridioides_phage	8.3e-08	27.8

Anti-CRISPR protein detection

Acr_ID: NZ_AP019840.1|WP_146995739.1|82885_83488_-|GNAT-family-N-acetyltransferase

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Acr_ID: NZ_AP019840.1|WP_026749678.1|245330_245705_-|hypothetical-protein

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Acr_ID: NZ_AP019840.1|WP_071124812.1|1607960_1608167_-|hypothetical-protein

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Acr_ID: NZ_AP019840.1|WP_146996933.1|1636743_1637325_-|GNAT-family-N-acetyltransferase

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Acr_ID: NZ_AP019840.1|WP_084533645.1|1637650_1638223_-|hypothetical-protein

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Acr_ID: NZ_AP019840.1|WP_146997509.1|2545351_2545576_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_AP019840.1|WP_146995739.1|82885_83488_-|GNAT-family-N-acetyltransferase

82885_83488_-

200 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.4742268041237113	0.955	0.9896373056994818

NZ_AP019840.1|WP_026749678.1|245330_245705_-|hypothetical-protein

245330_245705_-

124 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|84	0.9435483870967742	1	1.0

NZ_AP019840.1|WP_071124812.1|1607960_1608167_-|hypothetical-protein

1607960_1608167_-

68 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|80	0.5076923076923077	0.9705882352941176	0.8783783783783784

1529620-1612952

NZ_AP019840.1|WP_146996933.1|1636743_1637325_-|GNAT-family-N-acetyltransferase

1636743_1637325_-

193 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.654639175257732	1	1.0

NZ_AP019840.1|WP_084533645.1|1637650_1638223_-|hypothetical-protein

1637650_1638223_-

190 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.4742268041237113	1	0.9948186528497409

NZ_AP019840.1|WP_146997509.1|2545351_2545576_-|hypothetical-protein

2545351_2545576_-

74 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|82	0.875	0.9864864864864865	0.9113924050632911

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP019840

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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