CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP042839	Enterococcus sp. DA9 chromosome, complete genome	3 crisprs	csa3,cas3,cas9,cas2,csn2,DEDDh,DinG	4	4
NZ_CP042836	Enterococcus sp. DA9 plasmid unnamed1	0 crisprs	NA	0	0
NZ_CP042840	Enterococcus sp. DA9 plasmid unnamed4	1 crisprs	csa3	1	2
NZ_CP042837	Enterococcus sp. DA9 plasmid unnamed2	0 crisprs	NA	0	0
NZ_CP042838	Enterococcus sp. DA9 plasmid unnamed3	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042839_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042839_1

408121-408256

Orphan

Consensus_repeat	Method
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042839_1

>merge|NZ_CP042839|1|408121-408256|CRISPRCasFinder
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTCTACTCGCTTTGCTCGAAAGGAAACTCCTTTCGCTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC

>NZ_CP042839|1|1|408121-408256|CRISPRCasFinder
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC	TACTCGCTTTGCTCGAAAGGAAACTCCTTTCG
CTTTGCTCAACCAGTATTGTTCATCATCTATTCTCTTCGTTCATAGTGATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042839.1\|WP_147606718.1\|403467_405000_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP042839.1\|WP_002291636.1\|408457_409147_-\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
NZ_CP042839.1\|WP_073490488.1\|410015_410684_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP042839.1\|WP_002287787.1\|402532_403234_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|238693
NZ_CP042839.1\|WP_002291633.1\|407123_407492_-\|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl\|CDD\|234671
NZ_CP042839.1\|WP_002291638.1\|409250_409673_-\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
NZ_CP042839.1\|WP_002345547.1\|400242_401382_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP042839.1\|WP_002320546.1\|412854_413736_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_CP042839.1\|WP_002294578.1\|414649_414802_-\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
NZ_CP042839.1\|WP_080491742.1\|411662_412763_-\|lactate-oxidase	unknown	unknown	gnl\|CDD\|240088
NZ_CP042839.1\|WP_086307486.1\|397305_398139_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_002309994.1\|414458_414629_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|376355
NZ_CP042839.1\|WP_002309997.1\|410696_411569_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP042839.1\|WP_002290559.1\|401560_402274_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NZ_CP042839.1\|WP_002291634.1\|407544_408048_-\|50S-ribosomal-protein-L10	unknown	unknown	gnl\|CDD\|234632
NZ_CP042839.1\|WP_002294580.1\|413812_414358_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_CP042839.1\|WP_002310000.1\|405055_406246_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP042839.1\|WP_147606720.1\|406327_407017_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP042839.1\|WP_087063222.1\|398125_399862_-\|DUF2264-domain-containing-protein	unknown	unknown	gnl\|CDD\|378358
NZ_CP042839.1\|WP_002309993.1\|414963_415608_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341358

Protein	Function_ID	Function_description	E-value
NZ_CP042839.1\|WP_147606718.1\|403467_405000_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	8.32254e-169
NZ_CP042839.1\|WP_002291636.1\|408457_409147_-\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	2.1815e-146
NZ_CP042839.1\|WP_073490488.1\|410015_410684_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	3.32031e-73
NZ_CP042839.1\|WP_002287787.1\|402532_403234_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	8.8122e-119
NZ_CP042839.1\|WP_002291633.1\|407123_407492_-\|50S-ribosomal-protein-L7/L12	gnl\|CDD\|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	4.29798e-45
NZ_CP042839.1\|WP_002291638.1\|409250_409673_-\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	9.059e-96
NZ_CP042839.1\|WP_002345547.1\|400242_401382_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.21472e-61
NZ_CP042839.1\|WP_002320546.1\|412854_413736_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	3.47235e-76
NZ_CP042839.1\|WP_002294578.1\|414649_414802_-\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	3.12722e-17
NZ_CP042839.1\|WP_080491742.1\|411662_412763_-\|lactate-oxidase	gnl\|CDD\|240088	cd04737, LOX_like_FMN, L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate dehydrogenase (MDH), and long chain hydroxyacid oxidase (LCHAO).	0
NZ_CP042839.1\|WP_002309994.1\|414458_414629_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	1.6158e-13
NZ_CP042839.1\|WP_002309997.1\|410696_411569_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	5.46875e-102
NZ_CP042839.1\|WP_002290559.1\|401560_402274_-\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.06034e-48
NZ_CP042839.1\|WP_002291634.1\|407544_408048_-\|50S-ribosomal-protein-L10	gnl\|CDD\|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	3.03735e-67
NZ_CP042839.1\|WP_002294580.1\|413812_414358_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	1.97252e-86
NZ_CP042839.1\|WP_002310000.1\|405055_406246_-\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.73004e-69
NZ_CP042839.1\|WP_147606720.1\|406327_407017_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.54043e-20
NZ_CP042839.1\|WP_087063222.1\|398125_399862_-\|DUF2264-domain-containing-protein	gnl\|CDD\|378358	pfam10022, DUF2264, Uncharacterized protein conserved in bacteria (DUF2264). Members of this family of hypothetical bacterial proteins have no known function.	2.87023e-140
NZ_CP042839.1\|WP_002309993.1\|414963_415608_+\|CBS-domain-containing-protein	gnl\|CDD\|341358	cd02205, CBS_pair_SF, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	3.98249e-14

>NZ_CP042839.1|WP_002291634.1|407544_408048_-|50S-ribosomal-protein-L10
MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRKQLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAKEAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVADKEDGDAA
>NZ_CP042839.1|WP_002291633.1|407123_407492_-|50S-ribosomal-protein-L7/L12
MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAAGGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSKEEADELKAKLEEVGASVTVK
>NZ_CP042839.1|WP_147606720.1|406327_407017_-|TVP38/TMEM64-family-protein
MKKKKIRLILITLGVVLILMVGYRLYLEYQTDIQLFLNPRASKEELLAHIRSHGFSASLLLIVLTAVMCAVPGIPTSVIGVIAGLSFGPFIGAGINVLGNALGNISAVFLMHRLKFLDKKTEKNHWVQSIRQMRHPKIGVMLGYMIPVIPFSMVNFAADAMKLPLQQIVMSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKDRKKKQGKQRQK
>NZ_CP042839.1|WP_002310000.1|405055_406246_-|MFS-transporter
MESKEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSVSTSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAISLLAAFFAPSFALFACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVASLFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTSVSYLDSLKSLPHLVASQRLLREAAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADSYSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGEAASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQFVVFREKKEN
>NZ_CP042839.1|WP_147606718.1|403467_405000_+|ATP-binding-cassette-domain-containing-protein
MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKSTLIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLSIEEFLKTAYAKEYEKEEKIAFLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNLSGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEFLDQITTHIADIEFGKITKYTGHLKQALKQKKQNRESYLRQYHAQQKQIEKTEAYIRKYKAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRPLLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDLYWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQLTMNQGNLLILDEPTNHIDQETKESLQDGIRKFPGTVIIVSHEQEFYQDLVQRVIEIEPK
>NZ_CP042839.1|WP_002287787.1|402532_403234_-|glucosamine-6-phosphate-deaminase
MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYKEMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDLEAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRFFDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNHDNVVVIIDEEAASKL
>NZ_CP042839.1|WP_002290559.1|401560_402274_-|MgtC/SapB-family-protein
MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILVCMGACIIALIQVEIASGALRDALAYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVTKQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLEIQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVIEELSVHKNITKLHLVSIAQ
>NZ_CP042839.1|WP_002345547.1|400242_401382_-|AI-2E-family-transporter
MQSRFKQSKLFFWTVELVLTIVGVYFILQMPNIFSPILKMLSAIFLPLLVAGFIYYMFDPIVVFLEKHRIPRVLGFLLTFLVVIILVVLAVMNVVPQLVEQTIQLTQSLPIYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASVTKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETLSAYISSTILDALIIGVMSFLAMRIFNQPYSLLLAVICGITNIIPYVGPFIGAVPAIIVGLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILGMLICIPVYAVIKTIILNIRKIYLLRKMEHVSEKLDSPKVLEETSE
>NZ_CP042839.1|WP_087063222.1|398125_399862_-|DUF2264-domain-containing-protein
MNQLKQNLFLTRRDFEEALEEIILPLKQELFNSEKPGVRLGSSGAVYDEKRAEMEAFIRPLWGLAPYWMNHETKDELKDVYRKKILKGMNPKDSFYWGDINDYDQYIVEMAALSLNLLLNRNYFFDELSGTSKQQLIHWLKQALDKKIPKNNWTFFKILIRIALKHCGESLDKEKMEAELRFIDTMYVGKGWYIDGKSSQKDYYVPFAFHYYGLIFAKLMKDDFPEWSEKFIYRAKEFTKDYIYYFDSDGEALPYGRSLIYRFAQGAFFSALIFAEVEAIPWGQIKTLLSNHMKQWMSHDIFTYDGRLSIGYHYENLVMAEGYNAPGSPYWALKVFLLLATKKEHPYWEAKPEPVNTKEKRLIDNGNMLLCQAKEGKHVLGYPHGLMIDGQAHAPAKYSKFVYSTKFGFSVPKAGITYEEGAFDNTLALSRDGEYFRTKKKVRSSEATETFVMYEWQPFQEVLIQTEIYPFGEWHVRFHEIYTTIPLEIREGGFSLLVKEPEITLSKDCAKIKETHVSQIIAIEGYEEAGIQVLEPNTSVFFPRTNLPYLKKKIEPGTHRFICLVGGIINGGEKNDPN
>NZ_CP042839.1|WP_086307486.1|397305_398139_-|hypothetical-protein
MIQIELKNKNNQVVIGKIDHEKKETVFSANGEEIAVLAIKNHTYEVGDKLVITKEKNDYYFVVQLDETLAPTLLYIPEKKWEYVIPLEETKASVETGFRSKRHHIYVRKAYDFEVESYRNVSTNPHDQKLISGAYPHAYANVETRNDVTFFAKNAIDGKFGNRSHGSYPFTSWGINQQKDATLTIDFGRSIQTDRVDLLFRGDYPHDSYWTEVSICFSDGETIKVSTTDTLEFQSFYFPEKMTSSVTLKNLKKAEDTSPFPALTQIEIFGREVITCT
>NZ_CP042839.1|WP_002291636.1|408457_409147_-|50S-ribosomal-protein-L1
MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEVAYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQKIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGKVTYRVDKAGNIHVPIGKVSFDDEKLVENFATIHDVLLKAKPSAAKGQYMKNVTITTTFGPGIHVDQASF
>NZ_CP042839.1|WP_002291638.1|409250_409673_-|50S-ribosomal-protein-L11
MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSSDQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE
>NZ_CP042839.1|WP_073490488.1|410015_410684_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGDQPDSVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSEKAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVPGMIAKVTGILSETNTNIGTMTVTRESKGESAIMIIEVDNPQVEETVRRLKHLPNIDSVNYFD
>NZ_CP042839.1|WP_002309997.1|410696_411569_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFLSIEELVDQAKAYSSVAELMIAVEMEMSGRSRSQIIAIMEKNLSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVNAKMGLICATPTAGSAGVVPGVLMAVRDRLGLSHEQQLEFLFTAGAFGLVIANNASISGAEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPCVKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTPTAKRLTEEILNKRS
>NZ_CP042839.1|WP_080491742.1|411662_412763_-|lactate-oxidase
MTYHTSNEEHPIDIVNIASLEGRVKERMEAGAFGYIRGGSEDEWTMKENTTSFNAKKIMPRILRGIDSADLHTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAADAAPDAPQFFQLYMSKDDGFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFPLPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITNLPVIVKGIQSPEDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEHVFKALASGADLVAIGRPIIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKSIDEVKNTKLMD
>NZ_CP042839.1|WP_002320546.1|412854_413736_-|alpha/beta-fold-hydrolase
MTNRIKNVCKHAATAALVLISLFAISGCQTTKTTAVSDKEKTVESSKVIEKTTIPTLFFHGYSGTENSFKGMLQRLEKNQKAVKELVLIVEADGQIQAEGDLSGKADNPMVQVLFADNKNNEWNQAEWIKSCLLYLKENYSIDKVNIVGHSMGGVSALRYLGTYGQDTSLPQVQTFTAIGAPFNDFVDDSGQSLTEELAKGPAVVSSRYQDYQQIIGNMPTTTRFFLIAGQLDEADLSDGTVPLNSALAVYALLKQHGNEVEEKIVKGENAAHSMLHENQEVDQLVSRFVWNE
>NZ_CP042839.1|WP_002294580.1|413812_414358_-|transcription-termination/antitermination-protein-NusG
MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVPEEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPAPLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVNIDMFGRETSTELDFDQVDKID
>NZ_CP042839.1|WP_002309994.1|414458_414629_-|preprotein-translocase-subunit-SecE
MKFLKSVKDEIKQVTWPNRKQLRKDTLVVIETSILFGLMFYVMDTAIQSLFGWILK
>NZ_CP042839.1|WP_002294578.1|414649_414802_-|50S-ribosomal-protein-L33
MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYTLHKETK
>NZ_CP042839.1|WP_002309993.1|414963_415608_+|CBS-domain-containing-protein
MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSGNIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAVLDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKYSSIASCITLDIEKDEYIRRTLITLPANTEPKVCETIINHLEKKNYKVVEIENLQNQEA

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Crispr_ID: NZ_CP042839_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042839_2

1112300-1112665

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CRT

5 spacers

csn2,cas2,cas9

The CRISPR arrays of NZ_CP042839_2

>merge|NZ_CP042839|2|1112300-1112665|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACAAAACCCGAAACGATTCATATCAATTTACTGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACTTAGGACTATCACGAAGCGGATCGACGTCTGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACAGACTTAAGAACTCAAACCCCTCTACAGAAGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACATTACCCAAAGGATCAAAATAATTTTTATCGTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAACCTGATTCTGCTTGGATGGTGAGATAAATAAGTTTTAGAGCTATGCTGATTTGAATACTACTCTAGC

>NZ_CP042839|2|1|1112300-1112599|PILER-CR
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AAAACCCGAAACGATTCATATCAATTTACT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTAGGACTATCACGAAGCGGATCGACGTCT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AGACTTAAGAACTCAAACCCCTCTACAGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATTACCCAAAGGATCAAAATAATTTTTATC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC

>NZ_CP042839|2|2|1112300-1112665|CRISPRCasFinder
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AAAACCCGAAACGATTCATATCAATTTACT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTAGGACTATCACGAAGCGGATCGACGTCT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AGACTTAAGAACTCAAACCCCTCTACAGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATTACCCAAAGGATCAAAATAATTTTTATC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTGATTCTGCTTGGATGGTGAGATAAATAA
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGC

>NZ_CP042839|2|1|1112300-1112665|CRT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AAAACCCGAAACGATTCATATCAATTTACT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	TTAGGACTATCACGAAGCGGATCGACGTCT
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	AGACTTAAGAACTCAAACCCCTCTACAGAA
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	ATTACCCAAAGGATCAAAATAATTTTTATC
GTTTTAGAGCTATGCTGATTTGAATGCTTCCAAAAC	CTGATTCTGCTTGGATGGTGAGATAAATAA
GTTTTAGAGCTATGCTGATTTGAATACTACTCTAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042839.1\|WP_002292507.1\|1113198_1113564_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NZ_CP042839.1\|WP_002292500.1\|1100987_1102121_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176243
NZ_CP042839.1\|WP_002316627.1\|1100642_1100957_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372928
NZ_CP042839.1\|WP_147606872.1\|1113724_1115152_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|311953
NZ_CP042839.1\|WP_147606870.1\|1106327_1110350_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP042839.1\|WP_002312699.1\|1115857_1118410_+\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP042839.1\|WP_147606874.1\|1118416_1119856_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375760
NZ_CP042839.1\|WP_002310648.1\|1111212_1111557_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP042839.1\|WP_002310656.1\|1119999_1120362_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197
NZ_CP042839.1\|WP_147606868.1\|1103890_1105621_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NZ_CP042839.1\|WP_025477152.1\|1102411_1103272_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_147606876.1\|1122444_1124091_+\|malonate-decarboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|379906
NZ_CP042839.1\|WP_002287569.1\|1105677_1105806_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_025478102.1\|1111546_1112209_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP042839.1\|WP_002287551.1\|1120549_1121407_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP042839.1\|WP_002310635.1\|1100455_1100659_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_002292523.1\|1124192_1124492_+\|malonate-decarboxylase-subunit-delta	unknown	unknown	gnl\|CDD\|188283
NZ_CP042839.1\|WP_087063967.1\|1112836_1113202_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NZ_CP042839.1\|WP_002310643.1\|1106121_1106319_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_025477154.1\|1121526_1122438_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|132175

Protein	Function_ID	Function_description	E-value
NZ_CP042839.1\|WP_002292507.1\|1113198_1113564_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	8.2154e-25
NZ_CP042839.1\|WP_002292500.1\|1100987_1102121_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	1.57106e-174
NZ_CP042839.1\|WP_002316627.1\|1100642_1100957_-\|hypothetical-protein	gnl\|CDD\|372928	pfam14145, YrhK, YrhK-like protein. The YrhK-like protein family includes the B. subtilis YrhK protein, which is functionally uncharacterized. Its expression is under the control of the motility sigma factor sigma-D. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 60 amino acids in length.	1.95591e-14
NZ_CP042839.1\|WP_147606872.1\|1113724_1115152_-\|DNA-binding-protein	gnl\|CDD\|311953	pfam08280, HTH_Mga, M protein trans-acting positive regulator (MGA) HTH domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions.	0.000788111
NZ_CP042839.1\|WP_147606874.1\|1118416_1119856_-\|hypothetical-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	3.76478e-37
NZ_CP042839.1\|WP_002312699.1\|1115857_1118410_+\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP042839.1\|WP_002310648.1\|1111212_1111557_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.51394e-45
NZ_CP042839.1\|WP_002310656.1\|1119999_1120362_+\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.50194e-20
NZ_CP042839.1\|WP_147606868.1\|1103890_1105621_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NZ_CP042839.1\|WP_147606876.1\|1122444_1124091_+\|malonate-decarboxylase-subunit-alpha	gnl\|CDD\|379906	pfam16957, Mal_decarbox_Al, Malonate decarboxylase, alpha subunit, transporter. Mal_decarbox_Al is a family of Na+-transporting carboxylic acid decarboxylases.	0
NZ_CP042839.1\|WP_025478102.1\|1111546_1112209_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.29943e-107
NZ_CP042839.1\|WP_002287551.1\|1120549_1121407_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.03447e-40
NZ_CP042839.1\|WP_002292523.1\|1124192_1124492_+\|malonate-decarboxylase-subunit-delta	gnl\|CDD\|188283	TIGR03130, malonate_delta, malonate decarboxylase acyl carrier protein. Members of this protein family are the acyl carrier protein, also called the delta subunit, of malonate decarboxylase. This subunit has the same covalently bound prosthetic group, derived from and similar to coenzyme A, as does citrate lyase, although this protein and the acyl carrier protein of citrate lyase do not show significant sequence similarity. Both malonyl and acetyl groups are transferred to the prosthetic group for catalysis.	5.72696e-47
NZ_CP042839.1\|WP_087063967.1\|1112836_1113202_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	6.87403e-22
NZ_CP042839.1\|WP_147606870.1\|1106327_1110350_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP042839.1\|WP_025477154.1\|1121526_1122438_+\|ACP-S-malonyltransferase	gnl\|CDD\|132175	TIGR03131, malonate_mdcH, malonate decarboxylase, epsilon subunit. Members of this protein family are the epsilon subunit of malonate decarboxylase. This subunit has malonyl-CoA/dephospho-CoA acyltransferase activity. Malonate decarboxylase may be a soluble enzyme, or linked to membrane subunits and active as a sodium pump. The epsilon subunit is closely related to the malonyl CoA-acyl carrier protein (ACP) transacylase family described by TIGR00128, but acts on an ACP subunit of malonate decarboxylase that has an unusual coenzyme A derivative as its prothetic group.	2.12109e-66

>NZ_CP042839.1|WP_025478102.1|1111546_1112209_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLEQPLSLEKATFLIVEDVTVFAKIVKWFYQYSESHELKLFNDKYKELKESDLLIITDVLGFDINSASTLKLIYADLERQLNEKVEVKSMIDKLTATISELIGYELLDHELDLEGDEITVLELFKALGIKIETRSDTIFEKLLELLQVYKYLSKKKLLVLINVCSYLTEEEISEVQNYISLYHMEVLFVEPRSIKGIKQFVLDKDYFLNLENMV
>NZ_CP042839.1|WP_002310648.1|1111212_1111557_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETADERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNPTASQAMLKRLKSNNPKKGFVTLLTVTEKQFARMVYLSGERDTSVANSDKRVIYLGEDEDAES
>NZ_CP042839.1|WP_147606870.1|1106327_1110350_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKEYTIGLDIGTNSVGWSVLTDDYRLVSKKMKVAGNTEKSSTKKNFWGVRLFDEGQTAEARRSKRTARRRLARRRQRILELQKIFAPEILKIDEHFFARLNESFLVLDEKKQSRHPVFATIKQEKSYHQTYPTIYHLRQALADSSEKADIRLVYLAMAHLLKYRGNFLIEGELNTENSSVTETFCQFLSTYNQQFSEAGDKQTEKLDEAVDCSFVFTEKMSKTKKAETLLKYFPHEKSNGYLSQFIKLMVGNQGNFKNVFGLEEEAKLQFSKETYEEDLEELLEKIGDDYIDLFVQAKNVYDAVLLSEILSDSTKNTRAKLSAGMIRRYDAHKEDLVLLKRFVKENLPKKYRAFFGDNSVNGYAGYIEGHATQEDFYKFVKKELTGIRGSEVFLTKIEQENFLRKQRTFDNGVIPHQIHLTELRAIIANQKKHYPFLKEEQEKLESLLTFKIPYYVGPLAKKQENSPFAWLIRKSEEKIKPWNLPEIVDMEGSAVRFIERMINTDMYMPHNKVLPKNSLLYQKFSIYNELTKVRYQDERGQMNYFSSIEKKEIFHELFEKNRKVTKKDLQEFLYLKYDIKHAELSGIEKAFNASYTTYHDFLTMSENKREMEQWLEDPELASMFEEIIKTLTVFEDREMIKTRLSHHEATLGKHIIKKLTKKHYTGWGRLSKELIQGIRDKQSNKTILDYLINDDDFPHHRNRNFMQLINDDSLSFKKEIKKAQMITDTENLEEIVKELTGSPAIKKGILQSLKIVDEIVGIMGYEPANIVVEMARENQTTGRGLKSSRPRLKALEESLKDFGSQLLKEYPTDNSSLQKDRLYLYYLQNGRDMYTGAPLDIHRLSDYDIDHIIPRSFTTDNSIDNKVLVSSKENRLKKDDVPSEKVVKKMRSFWYDLYSSKLISKRKLDNLTKIKLTEEDKAGFIKRQLVETRQITKHVAGILHHRFNKAEDTNEPIRKVRIITLKSALVSQFRNRFGIYKVREINEYHHAHDAYLNGVIALALLKKYPQLAPEFVYGEYLKFNAHKANKATVKKEFYSNIMKFFESDTPVCDENGEIFWDKSKSIAQVKKVINHHHMNIVKKTEIQKGGFSKETVEPKKDSSKLLPRKNNWDPAKYGGLGSPNVAYTVAFTYEKGKARKRTNALEGITIMEREAFEQSPVLFLKNKGYEQAEIEMKLPKYALFELENGRKRMVASNKEAQKANSFLLPEHLVTLLYHAKQYDEISHKESFDYVNEHHKEFSEVFARVLEFAGKYTLAEKNIEKLEKIYKENQTDDLAKLASSFVNLMQFNAMGAPADFKFFDVTIPRKRYTSLTEIWQSTIIHQSITGLYETRIRMGK
>NZ_CP042839.1|WP_002310643.1|1106121_1106319_+|hypothetical-protein
MILKSKAQKKRREQRCFKKADDGQSLILTCYIDLNATNIFIIAKITAFTIGVFVFSIMMSCWMKG
>NZ_CP042839.1|WP_002287569.1|1105677_1105806_-|hypothetical-protein
MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI
>NZ_CP042839.1|WP_147606868.1|1103890_1105621_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAEEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDNITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQEEEHVTVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITSLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSKVDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKCLNNQEVVKKLPCIK
>NZ_CP042839.1|WP_025477152.1|1102411_1103272_+|hypothetical-protein
MKQIQNKWNKRIIVMISSVCLFCLTVMLCLISTLANQHFMLEQNMQSDYAKKVAAEINQEIQSYHYEIGAPAEALEKIVSEELVQKNIELFIRNRYEKEPVELIGEKEVEEKLQEIINTYKQEEAEDDPFASEENNLLIYMTSGIFRRGIQSIYLMSFIDQILTIRERMVSFLPVISSILLVLLSGVFYLYRMSWKKVLWSFAVVIGGAGFQLLSLSVSLYLYDMTSQLDIRTQALQHLLDTYILSFIQFFSVVAIVEVVIAAGLWWIGKRVNTEKKVFSKRNEYK
>NZ_CP042839.1|WP_002292500.1|1100987_1102121_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAVTWQGKQKMEIRNVDDPRILEPTDAIIRITATAICGSDLHLYHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMESQCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNNLPDEKVLFLSDILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKAANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGTISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYEMIAEGLFDPTQIITHSLPLEEAAQAYEIFDKKEDKNIKVVLKP
>NZ_CP042839.1|WP_002316627.1|1100642_1100957_-|hypothetical-protein
MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLLTGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKRTRKKHGKAV
>NZ_CP042839.1|WP_002310635.1|1100455_1100659_-|hypothetical-protein
MGRPFSLLHAFLLFLCCAYFAYCDSKKFLSIEQFFGFLLYMLFHVPTLTAAFGTLAQEFLHYPEPSR
>NZ_CP042839.1|WP_087063967.1|1112836_1113202_+|DUF1622-domain-containing-protein
MFNTQLIGYLEWIIAILNICSIGILVAGIVLVLFKLFDWSHVKKNYAERNARNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVISYFLNQEIEDKEKQRRGEVG
>NZ_CP042839.1|WP_002292507.1|1113198_1113564_+|DUF1622-domain-containing-protein
MTTELMQFLLPYFEKLVLGLDIFAICLLIWGVCLSIKDFLKYLFVHTEAKNDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIRTIISYFLNKEIGPVDVPNK
>NZ_CP042839.1|WP_147606872.1|1113724_1115152_-|DNA-binding-protein
MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLNDINNIKKEFEEQIVYTHREKDCYTLYFSEHIPRCKIMQQLTQNSLFLKTCLLYLEENEPDYLQLTECEFISVSKAYSLKKQVLAYFHDCGIEIDRYSPRFTEMERRLLLLNVAYRLGSFKSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQLCTVTIDPTFIEEIKKRPIYNYVESAWETTDFQTYYKKEEFAFILTLFNLCNYGCHSYQLIAEDFQQLHQVFIDNTPEIKELVATFETHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTLFSSWAKRLPYDLRFNPNCMRAFVIELSGILRLTKERLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYASISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIERAIVSAVQNK
>NZ_CP042839.1|WP_002312699.1|1115857_1118410_+|HAD-IC-family-P-type-ATPase
MNWYKLTVEDTLKNHQTSTEGLSQEERQKRLTDQGYNEIEARQQTKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEESLNGLKQLMGQEAIVLSNGMQVKIPAKELVKGDVIVLRAGYVVPADVRLIEVHDLLVEESILTGESEASEKNHSVLAAEESIGDQKNMAFSGTLVQSGSAVGVVVETGNTTEIGKINQALQSVEQQTTPLIKKINRLNKQIFQGILCLILFLVVFTTFRYGMDWHILLSAMIALVVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNEMTVVDVAAKEETRVLSIMKNCQELKTKEEQKIENLSGNPTELALIRHTETANLPLKKIEAKIPFSSEYKYMATMHTEEKGTVIYVKGAPEVLLAKSTLSYSEQEAWGQTATAFAKKGQRVLGFAYKKVDSKQELTHESLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKMITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSEEELTRQVPKVDVFARTTPEHKLRIVKALQKNGEIVGMTGDGVNDAPALKRADIGIAMGIKGSEVSKQAADMVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALILNRPLPLSPVQILWVNMVTTITLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVALLIMVPAYLLAMQFEGQSLQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKSLFLSLGILALLQGMVIFLPIAQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREFSR
>NZ_CP042839.1|WP_147606874.1|1118416_1119856_-|hypothetical-protein
MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIRTTERTIFSDLQSIRSHLPEGWDIFSDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLFTKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFYHRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWLFINTIRIKANCRLDSSIHINSTLSSLYDSALKKLYLKEGIYLKDTELSFASFCFLESWNYNNNYGQEIARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLVLKYHESPILIEPLERQYHRFLETYDQQYAHLYQQKENLLNDLKKEMEINVPNYFLQLLSLLIQQTIFSIKPNLFNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDSLDIPIVYISSIPTKNELNRLTELTFKTFL
>NZ_CP042839.1|WP_002310656.1|1119999_1120362_+|hypothetical-protein
MLTEKELIDHIDETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVLMSVPEEKIYDDASDHRIIDILDLKVDPELGGILRGKEGYFPAYHMNKEHWISVDLRKIEKLDELAGLIDESFKSTQ
>NZ_CP042839.1|WP_002287551.1|1120549_1121407_-|LysR-family-transcriptional-regulator
MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELGVPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASVSIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAIPKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATLRSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAKTMREFYLGK
>NZ_CP042839.1|WP_025477154.1|1121526_1122438_+|ACP-S-malonyltransferase
MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENYQDTVFIQLALLTKAVFYLDEMEKNGIQPDIVAGHSIGAFCAAVACRSLTFENAAELVYHRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSIEGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLFDARCLYIKNTDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKFGVDKGIRTINLDQHGIDDATFLYQKWR
>NZ_CP042839.1|WP_147606876.1|1122444_1124091_+|malonate-decarboxylase-subunit-alpha
MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLIAPGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKIDFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNLYTGFNTEETPTIVEAAAFKDGIVIVQVNEVVDKLPRVDIPGDWVDVVVKADQPYQLEALFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLKGKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSNRTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPAWQSLRNNYDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSEDTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDRLRDAGIVKLPEDLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS
>NZ_CP042839.1|WP_002292523.1|1124192_1124492_+|malonate-decarboxylase-subunit-delta
MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKKESTVKICTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK

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Crispr_ID: NZ_CP042839_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042839_3

2383393-2383486

Orphan

Consensus_repeat	Method
TGAGGAAGAAGGTGTTGTTTCTGCTGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042839_3

>merge|NZ_CP042839|3|2383393-2383486|CRISPRCasFinder
TGAGGAAGAAGGTGTTGTTTCTGCTGCATTGCTGCTTGAATCCCCTGCTTGATAAGTTGTGTCACTTGAGGAAGAAGGTGTTGTCTCTGCTGCA

>NZ_CP042839|3|3|2383393-2383486|CRISPRCasFinder
TGAGGAAGAAGGTGTTGTTTCTGCTGCA	TTGCTGCTTGAATCCCCTGCTTGATAAGTTGTGTCACT
TGAGGAAGAAGGTGTTGTCTCTGCTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042839.1\|WP_002290187.1\|2372646_2373102_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_002316165.1\|2386772_2387510_-\|carboxymethylenebutenolidase	unknown	unknown	gnl\|CDD\|315383
NZ_CP042839.1\|WP_147607091.1\|2374571_2374904_-\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212138
NZ_CP042839.1\|WP_087063062.1\|2393360_2394122_-\|segregation/condensation-protein-A	unknown	unknown	gnl\|CDD\|234635
NZ_CP042839.1\|WP_002290177.1\|2379651_2380962_-\|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl\|CDD\|234628
NZ_CP042839.1\|WP_002309587.1\|2376008_2376590_-\|IDEAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|235145
NZ_CP042839.1\|WP_002313886.1\|2392084_2392801_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP042839.1\|WP_002290180.1\|2376595_2377855_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP042839.1\|WP_002309605.1\|2391143_2391755_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|226129
NZ_CP042839.1\|WP_002344136.1\|2373255_2374464_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|237339
NZ_CP042839.1\|WP_002320679.1\|2381143_2382373_-\|30S-ribosomal-protein-S1	unknown	unknown	gnl\|CDD\|235851
NZ_CP042839.1\|WP_002309607.1\|2392801_2393377_-\|SMC-Scp-complex-subunit-ScpB	unknown	unknown	gnl\|CDD\|234657
NZ_CP042839.1\|WP_002309598.1\|2385327_2386359_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227291
NZ_CP042839.1\|WP_002290168.1\|2389240_2390764_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP042839.1\|WP_002309586.1\|2375051_2375927_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP042839.1\|WP_002309590.1\|2377856_2378903_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042839.1\|WP_002313884.1\|2387663_2389004_-\|Sapep-family-Mn(2+)-dependent-dipeptidase	unknown	unknown	gnl\|CDD\|235965
NZ_CP042839.1\|WP_147607093.1\|2383937_2385341_-\|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl\|CDD\|223588
NZ_CP042839.1\|WP_002309599.1\|2386389_2386611_+\|ferredoxin	unknown	unknown	gnl\|CDD\|224064
NZ_CP042839.1\|WP_147607092.1\|2382507_2383188_-\|(d)CMP-kinase	unknown	unknown	gnl\|CDD\|234579

Protein	Function_ID	Function_description	E-value
NZ_CP042839.1\|WP_002316165.1\|2386772_2387510_-\|carboxymethylenebutenolidase	gnl\|CDD\|315383	pfam12695, Abhydrolase_5, Alpha/beta hydrolase family. This family contains a diverse range of alpha/beta hydrolase enzymes.	6.38944e-73
NZ_CP042839.1\|WP_147607091.1\|2374571_2374904_-\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212138	cd11531, NTP-PPase_BsYpjD, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs. This family includes a putative pyrophosphatase Ypjd from Bacillus subtilis (BsYpjD) and its homologs. Although its biological role has not been described in detail, BsYpjD shows significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, BsYpjD contains a single MazG-like domain.	1.91355e-43
NZ_CP042839.1\|WP_087063062.1\|2393360_2394122_-\|segregation/condensation-protein-A	gnl\|CDD\|234635	PRK00104, scpA, segregation and condensation protein A; Reviewed.	7.68575e-91
NZ_CP042839.1\|WP_002290177.1\|2379651_2380962_-\|ribosome-biogenesis-GTPase-Der	gnl\|CDD\|234628	PRK00093, PRK00093, GTP-binding protein Der; Reviewed.	0
NZ_CP042839.1\|WP_002309587.1\|2376008_2376590_-\|IDEAL-domain-containing-protein	gnl\|CDD\|235145	PRK03636, PRK03636, hypothetical protein; Provisional.	1.62848e-61
NZ_CP042839.1\|WP_002313886.1\|2392084_2392801_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	4.27886e-102
NZ_CP042839.1\|WP_002309599.1\|2386389_2386611_+\|ferredoxin	gnl\|CDD\|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	1.01037e-12
NZ_CP042839.1\|WP_002309605.1\|2391143_2391755_-\|ECF-transporter-S-component	gnl\|CDD\|226129	COG3601, COG3601, Predicted membrane protein [Function unknown].	7.22947e-38
NZ_CP042839.1\|WP_002344136.1\|2373255_2374464_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|237339	PRK13299, PRK13299, tRNA CCA-pyrophosphorylase; Provisional.	0
NZ_CP042839.1\|WP_002320679.1\|2381143_2382373_-\|30S-ribosomal-protein-S1	gnl\|CDD\|235851	PRK06676, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP042839.1\|WP_002309607.1\|2392801_2393377_-\|SMC-Scp-complex-subunit-ScpB	gnl\|CDD\|234657	PRK00135, scpB, segregation and condensation protein B; Reviewed.	8.8191e-67
NZ_CP042839.1\|WP_002309598.1\|2385327_2386359_-\|hypothetical-protein	gnl\|CDD\|227291	COG4955, COG4955, Uncharacterized protein conserved in bacteria [Function unknown].	4.74889e-24
NZ_CP042839.1\|WP_002290168.1\|2389240_2390764_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	6.5543e-165
NZ_CP042839.1\|WP_002309586.1\|2375051_2375927_+\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	5.34929e-87
NZ_CP042839.1\|WP_002313884.1\|2387663_2389004_-\|Sapep-family-Mn(2+)-dependent-dipeptidase	gnl\|CDD\|235965	PRK07205, PRK07205, hypothetical protein; Provisional.	0
NZ_CP042839.1\|WP_147607093.1\|2383937_2385341_-\|RecQ-family-ATP-dependent-DNA-helicase	gnl\|CDD\|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	1.82545e-157
NZ_CP042839.1\|WP_002290180.1\|2376595_2377855_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	2.50473e-14
NZ_CP042839.1\|WP_147607092.1\|2382507_2383188_-\|(d)CMP-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	2.75913e-117

>NZ_CP042839.1|WP_147607092.1|2382507_2383188_-|(d)CMP-kinase
MTQISITIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYLAITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFTASKDVTLEIRQPDVTKAVSEVSAHGKVREELVAIQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKENQEKGIPTDLETLTKEIQARDHYDSTREVSPLQQAEDAVRIDTTGKSIPEVVAAIKAVVLEKGYLLF
>NZ_CP042839.1|WP_002320679.1|2381143_2382373_-|30S-ribosomal-protein-S1
MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIIGIEGAGVEGVVPAKELSTLPVEDINEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRLDAKKVWEDIERDFQDGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYKGKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFGAFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDEVNVKVLSINPEQERVSLSIKDTQPGPWSEIDTKAPVGAVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLHEGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILGDALKEEVEEKATDDSEK
>NZ_CP042839.1|WP_002290177.1|2379651_2380962_-|ribosome-biogenesis-GTPase-Der
MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYAKGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEMVAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAVKYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFVSESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDKRVAGYAHEAGRGVIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQRLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKPPTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK
>NZ_CP042839.1|WP_002309590.1|2377856_2378903_-|hypothetical-protein
MELDYQVEEALTKVFYGETLVSQLRALSIDQPILFLTNQRYYDLFADKINPLFANQANNDWYICANTQCNHLTELKNLLDFTKRYPENQSMFVIGFGNEGIMDLAGFFQKHTILDSSLWLIPVSIRSLSRALTPQRTILQLPNRVVLQTINMPERIVYDQTISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFYQLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFFVWLDLLGYPIQWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQRPNEKELLRTMTVFQQIVSEIRGN
>NZ_CP042839.1|WP_002290180.1|2376595_2377855_-|tetratricopeptide-repeat-protein
MNTNSEKMLQALSDEDLAQAQLFLEKALKEDPADILAELGEELLAIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKESDYYPQSLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVIYETLLASGINEMSGISMQERLGQSLSMQGEFEAAIAPLEEALKEEKTDDRLFQLAFTNLQLKENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMVEEAQTVLEEGIKENPYQVELYHLASENAFRLHDKQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQMEETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRAQELLTHYLKLEPGDMEALSLLDDLTER
>NZ_CP042839.1|WP_002309587.1|2376008_2376590_-|IDEAL-domain-containing-protein
MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVHFVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECLFENAWQTREYLSILEDNPFSSWDASVSEEDTELIERYFQEKEEAAKLNMLYAQIDQALEDGDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN
>NZ_CP042839.1|WP_002309586.1|2375051_2375927_+|YitT-family-protein
MATRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLILRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEINLQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGISMGRSLLAFDIIVLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTGLQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQGFTYLKPQTRLLKKL
>NZ_CP042839.1|WP_147607091.1|2374571_2374904_-|nucleotide-pyrophosphohydrolase
MDEKRSLYSMQQEVDEYIQQFKVGYFSPLAQLARLTEEVGELAREVNHAYGEKSKKASEPDNSVAEELGDVLFVTMIMANSLNIDLTDVFEKNMEKFNQRDHNRFERKAK
>NZ_CP042839.1|WP_002344136.1|2373255_2374464_-|CCA-tRNA-nucleotidyltransferase
MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIHDVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDHVEFVRSLEEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDALRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERSAGIHAFIKTECYICCPGLREEGEALLRFAELPSVPLKEESQAWTLLISQLDLKENEIRSFLKSWKCSNQMIKDVQALVQGLRQRKTGVLEPFELYFLGKKHALQVEELMTYFDETPQMDVVEESYDRLPIKSLSELAVDGKILLEESGKKPGKWVSEALQSAEKAVVEQRIENDKKQVLDFLSKEKLI
>NZ_CP042839.1|WP_002290187.1|2372646_2373102_-|hypothetical-protein
MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSEFVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPDLVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE
>NZ_CP042839.1|WP_147607093.1|2383937_2385341_-|RecQ-family-ATP-dependent-DNA-helicase
MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSLCYQLTGYLMDGMVLIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSRAERGYVLRHLSQYKFLFLSPEMLTNPSLLEQLKKQDIALYVVDEAHCVSQWGVDFRPEYQQLGKIREHLGNPVTLALTATATDLVAKDIRQVLFDRQPKEVRQSVNRQNISLFVRKTQQKEQELEQFMERAQGAAIIYCATKKEVERLYHLFRERFSVGYYHGGLDTAQRRQLQQQFVKNQLQFLIATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILLYQSGDERIHYFFNQLSREQRQSFELYLEYTAEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEKEFRLQQMLRYIHEEDCRRKFILAYFGEELSEKPQNCCDIDGAKVELLPKKKAFSKTEPLHWESILLNLFKKNMEH
>NZ_CP042839.1|WP_002309598.1|2385327_2386359_-|hypothetical-protein
MIVFILSLFSSRNKLRVSSLYQLLVGKRTTSVLIFGFTHELLFAHNSFPELKQDKFSQIMQKLAQQGWIEINENEAKLTSAGADRLSELHTEYTGLRFDRYGRTGETSWRLIKFAVQVISNLASGNQNYLPAETSPFYTFQLKKWLSGSRLSRGILIDSAYESLAQLFSEIPEGAADFLANQFSGNDRTGLLPYQLAKTNDESAVYLQQSRCIHLLLAQIEERPDSLWYVLIDPLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKKGTVTDHLIEWALFFDDFPYERILSQETVERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLRKEAIQNVNK
>NZ_CP042839.1|WP_002309599.1|2386389_2386611_+|ferredoxin
MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQQFVMPEEEAYVRKAYQKCPVRAILLENKI
>NZ_CP042839.1|WP_002316165.1|2386772_2387510_-|carboxymethylenebutenolidase
MKIFRRILIGLVIILGLLGGGGYYYIQQNTYEPSSEAQKVVKEGRNKEDYLFFEGEKKNQAKSPLLIFYPGALVDPESYSIWAQDLAKNGYSVAIVKMPLDLAVIGGNKADKIKEDFPDSDYVIGGHSLGGVMASRYANKNHSDSHLKGVFFMASYPDKKGTLKESAVPVLSITATKDKVLNQKAYEEAKQYLPERTEYVSINGGNHGGFGSYGEQKGDGEAEISNADQQTVIVNTLENWLKKLK
>NZ_CP042839.1|WP_002313884.1|2387663_2389004_-|Sapep-family-Mn(2+)-dependent-dipeptidase
MKQFVTEQHHEQALESLSELIRIPSVLDEADSGKGHPFGKKVIEALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPFDPTVKDGWLVGRGSQDDKGPSIAAMYAVKALMDAGVEFKTRIRFIFGTDEENLWRCLEKYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNDFSVKAGGALNVVPDAAPYSGEKISEVKEALKKHGFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIVLSEVFDFGPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFKKEDLVAKLTKTAEKYELSYEEFDFLDSLYVPLDSELVKNLLGTYREITGDMTEPFVSGGATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK
>NZ_CP042839.1|WP_002290168.1|2389240_2390764_-|YfcC-family-protein
MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGNIVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGIINKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMMAVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLAISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFITFGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFLVMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWGEQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITAYQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF
>NZ_CP042839.1|WP_002309605.1|2391143_2391755_-|ECF-transporter-S-component
MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIPVLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSVKKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLIGIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQLEQRHTAVK
>NZ_CP042839.1|WP_002313886.1|2392084_2392801_-|rRNA-pseudouridine-synthase
MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGKHDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLDYDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLAKGIKIEGRKTSPAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLRPGDYRELNKKEVSSLLNHSK
>NZ_CP042839.1|WP_002309607.1|2392801_2393377_-|SMC-Scp-complex-subunit-ScpB
MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVANLVKELRDSYAQNPHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQPITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLEELPDTQEMEISLEEDVSPDLFFDGMNKGEQL
>NZ_CP042839.1|WP_087063062.1|2393360_2394122_-|segregation/condensation-protein-A
MTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPIQEFVTDDEELWEEDPREELVTQLLEYRKYKYAAEKLTEKAEERSLYYTKDPMNIDGLADVEKPLKRGQVKKIDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMIFIEERIKRNTHGCTFDSFFESPSKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYLAVGDTEHDEIK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	NZ_KY086101	Rice orange leaf phytoplasma strain ROL1 plasmid pROL1, complete sequence	2729-2758	6	0.8
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	563634-563663	6	0.8
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	NZ_CP035950	'Catharanthus roseus' aster yellows phytoplasma strain De Villa plasmid unnamed1, complete sequence	1219-1248	6	0.8
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	NC_019244	Periwinkle leaf yellowing phytoplasma plasmid p08PLY-1, complete sequence	1900-1929	6	0.8
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	NC_019246	Periwinkle leaf yellowing phytoplasma plasmid p05PLY-2, complete sequence	1954-1983	6	0.8
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	NC_003353	Aster yellows phytoplasma plasmid extrachromosomal DNA, complete sequence	2836-2865	6	0.8
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	AP013398	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S30-C38	27225-27254	6	0.8
NZ_CP042839_2	2.2\|1112402\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112402-1112431	30	MT104473	Pseudomonas phage MR13, complete genome	13306-13335	7	0.767
NZ_CP042839_2	2.2\|1112402\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112402-1112431	30	MT104475	Pseudomonas phage MR15, complete genome	13287-13316	7	0.767
NZ_CP042839_2	2.3\|1112468\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112468-1112497	30	NZ_HG917973	Mycobacterium marinum E11 plasmid pRAW, complete sequence	57467-57496	7	0.767
NZ_CP042839_2	2.3\|1112468\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112468-1112497	30	NZ_AP018497	Mycobacterium marinum strain ATCC 927 plasmid pMMRN, complete sequence	4502-4531	7	0.767
NZ_CP042839_2	2.1\|1112336\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112336-1112365	30	NZ_MK422609	Psychrobacter sp. DAB_AL32B plasmid pP32BP2, complete sequence	26395-26424	8	0.733
NZ_CP042839_2	2.1\|1112336\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112336-1112365	30	NC_010630	Nostoc punctiforme PCC 73102 plasmid pNPUN03, complete sequence	17810-17839	8	0.733
NZ_CP042839_2	2.4\|1112534\|30\|NZ_CP042839\|PILER-CR,CRISPRCasFinder,CRT	1112534-1112563	30	AP014024	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C114-MedDCM-OCT-S41-C54, * SEQUENCING IN PROGRESS *	49-78	8	0.733

1. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY086101 (Rice orange leaf phytoplasma strain ROL1 plasmid pROL1, complete sequence) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
aatccccaaatgattaaaataattttttta	Protospacer
* * ****** ***.************ *

2. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
atcttctaaattatcaaaataatttttatc	Protospacer
**. .*.***  ******************

3. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035950 ('Catharanthus roseus' aster yellows phytoplasma strain De Villa plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
aatccccaaaggattaaaataatatttttt	Protospacer
* * **********.******** *** *.

4. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NC_019244 (Periwinkle leaf yellowing phytoplasma plasmid p08PLY-1, complete sequence) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
aatccccaaaggattaaaataatctttttt	Protospacer
* * **********.********.*** *.

5. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NC_019246 (Periwinkle leaf yellowing phytoplasma plasmid p05PLY-2, complete sequence) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
aatccccaaaggattaaaataatctttttt	Protospacer
* * **********.********.*** *.

6. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NC_003353 (Aster yellows phytoplasma plasmid extrachromosomal DNA, complete sequence) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
aatccccaaaggattaaaataatctttttt	Protospacer
* * **********.********.*** *.

7. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to AP013398 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S30-C38) position: , mismatch: 6, identity: 0.8

attacccaaaggatcaaaataatttttatc	CRISPR spacer
ttttgcaaaaggatcaaagtaagttttatc	Protospacer
 **  * ***********.*** *******

8. spacer 2.2|1112402|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to MT104473 (Pseudomonas phage MR13, complete genome) position: , mismatch: 7, identity: 0.767

ttaggactatcacgaagcggatcgacgtct	CRISPR spacer
tcgtgaccatcacgaagcggatcaacggcg	Protospacer
*.. ***.***************.*** *

9. spacer 2.2|1112402|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to MT104475 (Pseudomonas phage MR15, complete genome) position: , mismatch: 7, identity: 0.767

ttaggactatcacgaagcggatcgacgtct	CRISPR spacer
tcgtgaccatcacgaagcggatcaacggcg	Protospacer
*.. ***.***************.*** *

10. spacer 2.3|1112468|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NZ_HG917973 (Mycobacterium marinum E11 plasmid pRAW, complete sequence) position: , mismatch: 7, identity: 0.767

agacttaagaactcaaacccctctacagaa	CRISPR spacer
accccaaggaactcaaacccctctacggat	Protospacer
*  *. *.******************.**

11. spacer 2.3|1112468|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018497 (Mycobacterium marinum strain ATCC 927 plasmid pMMRN, complete sequence) position: , mismatch: 7, identity: 0.767

agacttaagaactcaaacccctctacagaa	CRISPR spacer
accccaaggaactcaaacccctctacggat	Protospacer
*  *. *.******************.**

12. spacer 2.1|1112336|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK422609 (Psychrobacter sp. DAB_AL32B plasmid pP32BP2, complete sequence) position: , mismatch: 8, identity: 0.733

aaaacccgaaacgattcatatcaatttact	CRISPR spacer
cctgtgcgaaacgattgatatcaattttct	Protospacer
   .. ********** ********** **

13. spacer 2.1|1112336|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to NC_010630 (Nostoc punctiforme PCC 73102 plasmid pNPUN03, complete sequence) position: , mismatch: 8, identity: 0.733

aaaacccgaaacgattcatatcaatttact	CRISPR spacer
aaaaccctaaacgtttcatatcacaacaga	Protospacer
******* ***** *********   .*

14. spacer 2.4|1112534|30|NZ_CP042839|PILER-CR,CRISPRCasFinder,CRT matches to AP014024 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C114-MedDCM-OCT-S41-C54, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.733

attacccaaaggatcaaaataatttttatc	CRISPR spacer
gctgtgcagaggatcaaaaaaatttttata	Protospacer
..*.. **.********** *********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5376 : 19620

Bacillus_phage(30.77%)

portal,terminase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002342088.1\|5376_6555_-\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	3.2e-80	40.4
WP_002286538.1\|8244_8559_-\|terminase	terminase	A0A1S7FYW6	Listeria_phage	3.3e-08	37.9
WP_002299164.1\|8661_8943_-	hypothetical protein	NA	NA	NA	NA
WP_002343377.1\|8947_9292_-	HNH endonuclease	A0A1B1P757	Bacillus_phage	1.7e-26	57.1
WP_002304479.1\|10278_10692_-	autolysin	C9E2P5	Enterococcus_phage	1.1e-56	81.0
WP_104832643.1\|10768_11065_-	hypothetical protein	NA	NA	NA	NA
WP_002323694.1\|11061_11283_-	hypothetical protein	NA	NA	NA	NA
WP_147606622.1\|11811_12204_-	hypothetical protein	A0A2H4JBP1	uncultured_Caudovirales_phage	2.6e-10	38.7
WP_002321589.1\|12187_12520_-	DUF1140 family protein	A0A2H4JAZ4	uncultured_Caudovirales_phage	2.8e-10	37.4
WP_147606624.1\|12519_12825_-	hypothetical protein	NA	NA	NA	NA
WP_002319167.1\|12821_12983_-	hypothetical protein	NA	NA	NA	NA
WP_147606626.1\|12997_13357_-	DUF1064 domain-containing protein	A0A1P8BKR1	Lactococcus_phage	6.8e-18	47.5
WP_104836944.1\|13353_14205_-	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.6e-25	29.1
WP_024635611.1\|14221_15052_-	replication protein	C9E2N2	Enterococcus_phage	1.5e-52	44.2
WP_024635610.1\|15054_15741_-	hypothetical protein	C9E2N1	Enterococcus_phage	2.4e-88	69.1
WP_002340820.1\|15746_16418_-	DUF1071 domain-containing protein	A0A1B1P7F0	Bacillus_phage	5.5e-29	47.4
WP_010725024.1\|16410_16752_-	hypothetical protein	NA	NA	NA	NA
WP_143352961.1\|17756_18059_+	hypothetical protein	NA	NA	NA	NA
WP_010752313.1\|18041_18224_-	hypothetical protein	NA	NA	NA	NA
WP_002317757.1\|18442_18763_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_002347912.1\|18775_18961_-	helix-turn-helix transcriptional regulator	Q5YAA3	Bacillus_phage	3.2e-11	53.3
WP_070676688.1\|19245_19620_+	helix-turn-helix transcriptional regulator	A0A2P0ZLA1	Lactobacillus_phage	3.4e-20	43.8

DBSCAN-SWA_2

36375 : 115412

Enterococcus_phage(44.44%)

tRNA,terminase,transposase,plate,capsid,head,integrase,holin,protease,tail,portal

attL 72460:72495|attR 114761:114796

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002346313.1\|36375_39174_-\|tRNA	isoleucine--tRNA ligase	A0A2H4UVG0	Bodo_saltans_virus	1.6e-74	26.4
WP_002291846.1\|39438_40146_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_002310283.1\|40166_40949_-	RNA-binding protein	NA	NA	NA	NA
WP_073490213.1\|40997_41285_-	YggT family protein	NA	NA	NA	NA
WP_147606637.1\|41299_41899_-	cell division protein SepF	NA	NA	NA	NA
WP_002310280.1\|41912_42590_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_002291854.1\|42606_43848_-	cell division protein FtsZ	NA	NA	NA	NA
WP_002291855.1\|43870_45196_-	cell division protein FtsA	NA	NA	NA	NA
WP_147606639.1\|45351_46584_-	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_002346310.1\|46598_47687_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_002314216.1\|47712_49074_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_002291862.1\|49087_50050_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_002310275.1\|50075_52268_-	penicillin-binding protein	NA	NA	NA	NA
WP_002297992.1\|52268_52670_-	cell division protein FtsL	NA	NA	NA	NA
WP_002345577.1\|52674_53634_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_002291870.1\|53654_54086_-	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_002310272.1\|54255_54624_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002291874.1\|54794_55751_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_002291876.1\|55823_55940_+	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_002316937.1\|55993_57676_-	DNA repair protein RecN	NA	NA	NA	NA
WP_002286653.1\|57693_58143_-	arginine repressor	NA	NA	NA	NA
WP_002310269.1\|58249_59068_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_002310268.1\|59076_59967_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002286657.1\|59968_60193_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_002310267.1\|60197_61535_-	exodeoxyribonuclease VII large subunit	L7RDW5	Acanthamoeba_polyphaga_moumouvirus	5.1e-26	29.0
WP_002310266.1\|61535_62390_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	3.1e-40	38.7
WP_002286662.1\|62486_62936_-	transcription antitermination factor NusB	NA	NA	NA	NA
WP_002291889.1\|62928_63354_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002310265.1\|63599_64664_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_002310264.1\|64836_65082_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002310263.1\|65219_65594_-	DUF956 family protein	NA	NA	NA	NA
WP_002310262.1\|65676_66591_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_002310261.1\|66611_67415_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_147606641.1\|67447_68437_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_002289455.1\|68539_69031_-	PTS transporter subunit IIB	NA	NA	NA	NA
WP_002334685.1\|69221_72056_-	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
72460:72495	attL	NA	NA	NA	NA
WP_024636555.1\|73560_73863_+	hypothetical protein	NA	NA	NA	NA
WP_147606643.1\|74628_75645_-	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	1.6e-64	58.8
WP_147606645.1\|75655_75853_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	1.7e-23	85.9
WP_147606647.1\|75875_76169_-	hypothetical protein	NA	NA	NA	NA
WP_002290625.1\|76206_76344_-	XkdX family protein	NA	NA	NA	NA
WP_002333072.1\|76584_77955_-	oligosaccharide repeat unit polymerase	NA	NA	NA	NA
WP_147606649.1\|78055_80305_-\|plate	BppU family phage baseplate upper protein	A6MAC6	Lactococcus_virus	1.8e-07	40.5
WP_147606651.1\|80304_81087_-	hypothetical protein	NA	NA	NA	NA
WP_147606652.1\|81103_82861_-\|plate	BppU family phage baseplate upper protein	A0A191KBJ0	Streptococcus_virus	5.5e-36	38.8
WP_147606654.1\|82835_85682_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1P8BMB8	Lactococcus_phage	0.0e+00	60.6
WP_147607130.1\|85678_86446_-\|tail	phage tail protein	D7RWD9	Brochothrix_phage	9.1e-60	45.5
WP_002318903.1\|89316_89604_-	hypothetical protein	D7RWD7	Brochothrix_phage	2.4e-13	44.3
WP_002293018.1\|89657_90026_-	hypothetical protein	Q77RZ7	Lactococcus_phage	8.6e-24	54.8
WP_002293017.1\|90071_90584_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	2.2e-57	66.3
WP_147607131.1\|90594_90987_-\|capsid	phage capsid protein	Q77K20	Lactococcus_phage	2.4e-48	74.6
WP_010722880.1\|90986_91325_-	HK97 gp10 family phage protein	Q77K21	Lactococcus_phage	1.3e-31	60.7
WP_073490895.1\|91691_92909_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.2e-68	37.4
WP_010725226.1\|93242_93572_-	hypothetical protein	A0A0S2MYD5	Enterococcus_phage	3.8e-39	76.4
WP_010725227.1\|93583_93847_-	hypothetical protein	D2J062	Enterococcus_phage	1.1e-09	74.4
WP_002322711.1\|93864_94788_-\|capsid	phage major capsid protein	A0A1B1V000	Enterococcus_phage	1.8e-139	77.5
WP_002322712.1\|94800_95403_-	DUF4355 domain-containing protein	A0A097BY91	Enterococcus_phage	1.1e-36	52.5
WP_104889530.1\|95564_96485_-\|head	phage head morphogenesis protein	A0A1L2JXH2	Streptococcus_phage	9.1e-91	57.0
WP_147606656.1\|96489_97989_-\|portal	phage portal protein	A0A097BY86	Enterococcus_phage	8.1e-222	78.9
WP_008274581.1\|98001_99300_-\|terminase	PBSX family phage terminase large subunit	A0A1B1UZZ1	Enterococcus_phage	1.3e-231	88.6
WP_002311445.1\|99292_99748_-\|terminase	terminase small subunit	D7RWC4	Brochothrix_phage	2.7e-19	41.4
WP_147606658.1\|99766_99997_-	hypothetical protein	NA	NA	NA	NA
WP_147606660.1\|100194_100569_-	hypothetical protein	NA	NA	NA	NA
WP_147606661.1\|100916_101315_-	hypothetical protein	NA	NA	NA	NA
WP_010706374.1\|101327_101741_-	ArpU family phage transcriptional regulator	C9E2P5	Enterococcus_phage	6.2e-55	79.6
WP_104833045.1\|101817_102114_-	hypothetical protein	NA	NA	NA	NA
WP_147606663.1\|102125_102314_-	toxin PIN	NA	NA	NA	NA
WP_147606665.1\|102408_103248_+	DUF4393 domain-containing protein	A0A0R6PH66	Moraxella_phage	1.7e-43	36.4
WP_147606666.1\|103392_104133_-	DUF1642 domain-containing protein	A0A0D3MVS9	Staphylococcus_phage	8.8e-28	60.0
WP_002322113.1\|104271_105087_-	prohibitin family protein	A0A288TXV9	Enterococcus_phage	2.8e-83	69.8
WP_002322112.1\|105083_105401_-	hypothetical protein	M4NJW7	Sulfitobacter_phage	7.7e-05	48.9
WP_002333651.1\|105633_105909_-	hypothetical protein	NA	NA	NA	NA
WP_071974467.1\|105908_106214_-	hypothetical protein	NA	NA	NA	NA
WP_002301517.1\|106210_106372_-	hypothetical protein	NA	NA	NA	NA
WP_002292987.1\|106368_106671_-	hypothetical protein	NA	NA	NA	NA
WP_104857089.1\|106832_107102_-	hypothetical protein	NA	NA	NA	NA
WP_147606668.1\|107113_107941_-	replisome organizer	A0A0S2MYA8	Enterococcus_phage	3.9e-40	54.9
WP_025481093.1\|107943_108171_-	hypothetical protein	NA	NA	NA	NA
WP_104867298.1\|108173_108860_-	hypothetical protein	C9E2N1	Enterococcus_phage	1.9e-88	69.9
WP_002322006.1\|108865_109600_-	DUF1071 domain-containing protein	A0A1X9IGE5	Lactococcus_phage	2.1e-42	48.4
WP_142972305.1\|109592_109934_-	hypothetical protein	NA	NA	NA	NA
WP_002311421.1\|110259_110448_-	hypothetical protein	D2IZW5	Enterococcus_phage	1.7e-07	58.6
WP_002333281.1\|110468_110753_-	hypothetical protein	NA	NA	NA	NA
WP_002330306.1\|110730_110943_-	helix-turn-helix transcriptional regulator	D2IZW2	Enterococcus_phage	2.6e-09	54.5
WP_002330307.1\|110945_111722_-	bro family toxin-antitoxin system toxin component	A0A0E3T9K2	Staphylococcus_phage	1.9e-73	55.5
WP_080105910.1\|111777_111999_+	hypothetical protein	NA	NA	NA	NA
WP_002301535.1\|112366_112714_+	helix-turn-helix transcriptional regulator	A0A097QQ00	Enterococcus_phage	9.2e-28	61.6
WP_002321996.1\|112749_113145_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_016628577.1\|113197_113509_+	hypothetical protein	NA	NA	NA	NA
WP_147606670.1\|113520_114669_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5S7K9	Streptococcus_phage	4.4e-66	39.8
WP_002289452.1\|114761_115055_-	50S ribosomal protein L27	NA	NA	NA	NA
114761:114796	attR	NA	NA	NA	NA
WP_002289451.1\|115067_115412_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA

DBSCAN-SWA_3

1723446 : 1733208

Streptococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002290404.1\|1723446_1724163_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.1e-34	36.2
WP_002313582.1\|1724162_1725611_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	6.0e-20	29.8
WP_002308814.1\|1725684_1726194_-	hypothetical protein	NA	NA	NA	NA
WP_147607017.1\|1726183_1726909_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_147607018.1\|1727080_1729201_-	sulfatase-like hydrolase/transferase	W6LM83	Streptococcus_phage	9.7e-221	58.4
WP_002308823.1\|1729429_1730608_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	6.0e-103	49.2
WP_002308824.1\|1730623_1731376_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.3e-26	35.9
WP_002290411.1\|1731398_1731884_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_147607019.1\|1731954_1733208_-	aminoacetone oxidase family FAD-binding enzyme	A0A2H4PQX1	Staphylococcus_phage	1.7e-23	55.3

DBSCAN-SWA_4

2281765 : 2290804

Synechococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002309479.1\|2281765_2282344_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-26	36.9
WP_033627216.1\|2282340_2283384_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.9e-61	43.9
WP_073490706.1\|2283415_2284855_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.1e-53	33.1
WP_073490707.1\|2284839_2287062_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.7e-152	41.4
WP_002313846.1\|2287062_2287734_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002309490.1\|2287735_2287990_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002313847.1\|2287989_2288718_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.1e-41	40.9
WP_002309492.1\|2288973_2289351_+	hypothetical protein	NA	NA	NA	NA
WP_147607083.1\|2289508_2290804_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	33.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP042838

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2977 : 30085

Enterococcus_phage(37.5%)

terminase,portal,capsid,head,holin,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086314952.1\|2977_4255_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	7.5e-168	69.2
WP_099746308.1\|4265_4463_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	7.8e-24	84.4
WP_002322123.1\|4478_4721_-\|holin	holin	D2J075	Enterococcus_phage	2.1e-23	68.4
WP_147606603.1\|4784_7664_-	hypothetical protein	A0A249XZH9	Enterococcus_phage	6.4e-98	54.7
WP_147606605.1\|7687_9979_-	hypothetical protein	A0A1D3SNL1	Enterococcus_phage	2.3e-90	30.1
WP_147606606.1\|9988_10726_-\|tail	phage tail protein	A0A2H4J851	uncultured_Caudovirales_phage	2.6e-19	31.9
WP_147606608.1\|10776_14493_-\|tail	phage tail tape measure protein	A0A1D3SNL5	Enterococcus_phage	1.5e-67	44.7
WP_002305377.1\|14509_14692_-	hypothetical protein	NA	NA	NA	NA
WP_002299170.1\|14694_15057_-	hypothetical protein	R4IBH8	Listeria_phage	3.0e-05	31.9
WP_002318244.1\|15078_15684_-	hypothetical protein	Q8W5Z9	Listeria_phage	6.7e-34	41.2
WP_147606610.1\|15695_16100_-	hypothetical protein	NA	NA	NA	NA
WP_147606612.1\|16092_16494_-	hypothetical protein	A0A1B1P759	Bacillus_phage	3.0e-14	34.1
WP_147606614.1\|16483_16837_-\|head,tail	head-tail adaptor protein	A0A1B1P760	Bacillus_phage	8.0e-11	38.5
WP_104880755.1\|16826_17138_-	hypothetical protein	A0A1B1P751	Bacillus_phage	2.7e-10	41.2
WP_147606616.1\|17134_18010_-	hypothetical protein	D2IYX3	Enterococcus_phage	4.3e-130	74.2
WP_002318250.1\|18019_19180_-\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	2.7e-100	50.4
WP_147606618.1\|19179_19866_-\|protease	Clp protease ClpP	A0A2I6PDD0	Staphylococcus_phage	1.8e-30	42.2
WP_002342088.1\|19828_21007_-\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	3.2e-80	40.4
WP_147606620.1\|21026_22721_-\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	5.5e-150	49.9
WP_002286538.1\|22698_23013_-\|terminase	terminase	NA	NA	NA	NA
WP_002343377.1\|23400_23745_-	HNH endonuclease	A0A1B1P757	Bacillus_phage	1.7e-26	57.1
WP_002304479.1\|24731_25145_-	autolysin	C9E2P5	Enterococcus_phage	1.1e-56	81.0
WP_104832643.1\|25221_25518_-	hypothetical protein	NA	NA	NA	NA
WP_002323694.1\|25514_25736_-	hypothetical protein	NA	NA	NA	NA
WP_147606622.1\|26264_26657_-	hypothetical protein	A0A2H4JBP1	uncultured_Caudovirales_phage	2.6e-10	38.7
WP_002321589.1\|26640_26973_-	DUF1140 family protein	A0A2H4JAZ4	uncultured_Caudovirales_phage	2.8e-10	37.4
WP_147606624.1\|26972_27278_-	hypothetical protein	NA	NA	NA	NA
WP_002319167.1\|27274_27436_-	hypothetical protein	NA	NA	NA	NA
WP_147606626.1\|27450_27810_-	DUF1064 domain-containing protein	A0A1P8BMB7	Lactococcus_phage	8.1e-19	51.4
WP_104836944.1\|27806_28658_-	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.6e-25	29.1
WP_147606631.1\|29506_30085_-	hypothetical protein	C9E2N1	Enterococcus_phage	2.5e-78	70.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP042840

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042840_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042840_1

39821-39949

Orphan

Consensus_repeat	Method
GGTATGATTTTCATACCCTCTTGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP042840_1

>merge|NZ_CP042840|1|39821-39949|CRISPRCasFinder
GGTATGATTTTCATACCCTCTGATTTATCAACGTTTTGGCACGGTATGATTTTCATACCCTCTTGAGCCCCAAGGGATTCAGCGTCTGATTTTTCGTCGAGGGTGGGTATGATTTTCATACCCTCTGAT

>NZ_CP042840|1|1|39821-39949|CRISPRCasFinder
GGTATGATTTTCATACCCTCTGAT	TTATCAACGTTTTGGCAC
GGTATGATTTTCATACCCTCTTGA	GCCCCAAGGGATTCAGCGTCTGATTTTTCGTCGAGGGTG
GGTATGATTTTCATACCCTCTGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042840.1\|WP_002311521.1\|37220_37562_-\|DUF5406-domain-containing-protein	unknown	unknown	gnl\|CDD\|379975
NZ_CP042840.1\|WP_099119708.1\|44785_44842_-\|LsbB-family-leaderless-bacteriocin	unknown	unknown	gnl\|CDD\|380237
NZ_CP042840.1\|WP_002311523.1\|36911_37202_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042840.1\|WP_002322486.1\|38180_38513_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042840.1\|WP_002293487.1\|32614_33367_-\|class-C-sortase	unknown	unknown	gnl\|CDD\|320676
NZ_CP042840.1\|WP_002313088.1\|45250_45466_-\|bacteriocin	unknown	unknown	gnl\|CDD\|366773
NZ_CP042840.1\|WP_002348857.1\|41728_41923_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042840.1\|WP_002311524.1\|36486_36720_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042840.1\|WP_002318791.1\|44908_45250_-\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|370205
NZ_CP042840.1\|WP_002318299.1\|42666_42921_+\|AbrB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|274230
NZ_CP042840.1\|WP_002293488.1\|31837_32599_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042840.1\|WP_000222573.1\|45908_46868_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP042840.1\|WP_147607156.1\|45689_45827_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234907
NZ_CP042840.1\|WP_002345834.1\|29477_31568_-\|isopeptide-forming-domain-containing-fimbrial-protein	unknown	unknown	gnl\|CDD\|375475
NZ_CP042840.1\|WP_002354485.1\|47824_48511_+\|IS6-like-element-IS1216-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP042840.1\|WP_143162214.1\|43702_44389_+\|IS6-like-element-IS1216-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP042840.1\|WP_002338747.1\|35409_36081_-\|class-A-sortase	unknown	unknown	gnl\|CDD\|320680
NZ_CP042840.1\|WP_002318298.1\|42921_43239_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NZ_CP042840.1\|WP_002293489.1\|31564_31825_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042840.1\|WP_142966042.1\|28986_29451_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042840.1\|WP_002311521.1\|37220_37562_-\|DUF5406-domain-containing-protein	gnl\|CDD\|379975	pfam17400, DUF5406, Family of unknown function (DUF5406). This is a family of unknown function found in Bacteria.	8.60138e-49
NZ_CP042840.1\|WP_099119708.1\|44785_44842_-\|LsbB-family-leaderless-bacteriocin	gnl\|CDD\|380237	NF033385, enterocin_LsbB, LsbB family leaderless bacteriocin. Members of this family are leaderless peptide components of bacteriocins with a conserved motif KXXXGXXPWE.	0.000223802
NZ_CP042840.1\|WP_002345834.1\|29477_31568_-\|isopeptide-forming-domain-containing-fimbrial-protein	gnl\|CDD\|375475	pfam17998, AgI_II_C2, Cell surface antigen I/II C2 terminal domain. This is the second domain (C2) located in the C-terminal region found in antigen I/II type adhesin protein AspA from S. pyogenes. Together with C3, these two domains form an elongated structure, each domain adopts the DEv-IgG fold. Similar to the classical IgG folds, it is comprised of two major antiparallel beta-sheets, designated ABED and CFG. For the C2-domain, there are two additional strands on the CFG sheet. Furthermore, sheets ABED and CFG are interconnected by several cross-connecting loops and one alpha-helix (DH1). The side chains of D982 and N996 in the C2-domain are involved in hydrogen bonding with the side chains of R1264 and N1295 in the C3 domain. Main chain hydrogen bonding can also be observed between S992 in C2 and N1189/G1191 in C3, furthermore stabilizing the interaction between the domains. The C2 domain contains one bound metal ion, modeled as Ca2+, and both the C2- and C3-domains are stabilized by conserved isopeptide bonds, which connect the beta-sheets of the central DEv-IgG motifs.Other members of this family include Major cell-surface adhesin PAc from Streptococcus mutans and SspB from Streptococcus gordonii.	4.64952e-14
NZ_CP042840.1\|WP_002293487.1\|32614_33367_-\|class-C-sortase	gnl\|CDD\|320676	cd05827, Sortase_C, Sortase domain found in class C sortases. Class C sortases are membrane-bound cysteine transpeptidases broadly distributed in Gram-positive bacteria (mainly present in Firmicutes and Actinobacteria). They function as pilin polymerases responsible for the assembly of pili, which are multi-subunit hair-like fibres that extend from the cell surface to promote microbial adhesion and biofilm formation. First, one or more class C sortases form the long thin shaft of the pilus through linking together pilin subunits via isopeptide bonds. The base of the pilus is then anchored to the cell wall by a housekeeping sortase or, in some cases, the class C sortase itself. Depending upon the organism both the number and type of sortase enzymes involved varies, and in some cases, accessory factors appear to be needed. In three-component spaA pilus from Corynebacterium diphtheriae, the prototypical class C sortase (named Cd-SrtA) catalyzes polymerization of the SpaA-type pilus, consisting of the shaft pilin SpaA, tip pilin SpaC and minor pilin SpaB. The pilus shaft is then attached to the cell wall by a housekeeping class E sortase, Cd-SrtF. In the absence of Cd-SrtF, Cd-SrtA attaches the pilus to the cell wall, albeit at a reduced rate. Cd-SrtA can recognize two distinct sorting signals (LPLTG in SpaA and SpaC, and LAFTG in SpaB) and it can employ lysine residues that originate from different proteins (either Lys190 within the pilin motif of SpaA or Lys139 in SpaB). However, Cd-SrtA cannot be able to polymerize the major pilin subunit SpaH, even though it contains LPLTG motif. In two-component pili of prototypical Bacillus cereus, the class C sortase (named Bc-SrtD) cleaves related sorting signals within a major pilin protein BcpA (LPVTG) and a minor tip pilin BcpB (IPNTG), and catalyzes a transpeptidation that joins the threonine residues in each signal to the side-chain of Lys162 in BcpA (located within a pilin motif). Unlike the SpaA pilus in C. diphtheriae, in B. cereus Bc-SrtD is unable to covalently attach the pilus to the cell wall without the help of the housekeeping sortase.	9.64363e-61
NZ_CP042840.1\|WP_000222573.1\|45908_46868_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.31608e-55
NZ_CP042840.1\|WP_002313088.1\|45250_45466_-\|bacteriocin	gnl\|CDD\|366773	pfam01721, Bacteriocin_II, Class II bacteriocin. The bacteriocins are small peptides that inhibit the growth of various bacteria. Bacteriocins of lactic acid bacteria may inhibit their target cells by permeabilising the cell membrane.	1.36604e-06
NZ_CP042840.1\|WP_002318791.1\|44908_45250_-\|bacteriocin-immunity-protein	gnl\|CDD\|370205	pfam08951, EntA_Immun, Enterocin A Immunity. Gram-positive lactobacilli produce bacteriocins to kill closely-related competitor species. To protect themselves from the bacteriocidal activity of this molecule they co-express an immunity protein (for discussion of this operon see Bacteriocin_IIc pfam10439). The immunity protein structure is a soluble, cytoplasmic, antiparallel four alpha-helical globular bundle with a fifth, more flexible and more divergent C-terminal helical hair-pin. The C-terminal hair-pin recognizes the C-terminus of the producer bacteriocin and this interaction is sufficient to dis-orient the bacteriocin within the membrane and close up the permeabilising pore that on its own the bacteriocin creates. These immunity proteins interact in the same way with other bacteriocins, family Bacteriocin_II, pfam01721. Since many enterococci can produce more than one bacteriocin it seems likely that the whole operon can be carried on transferable plasmids.	0.000109586
NZ_CP042840.1\|WP_002318299.1\|42666_42921_+\|AbrB-family-transcriptional-regulator	gnl\|CDD\|274230	TIGR02609, hypothetical_protein_XAC1195, putative addiction module antidote. Members of this protein family are putative addiction module antidote proteins that appear recurringly in two-gene operons with members of the Doc (death-on-curing) family TIGR01550. Members of this family contain a SpoVT/AbrB-like domain (pfam04014). Note that the gene pairs with a member of this family tend to be found on bacterial chromosomes, not on plasmids. [Mobile and extrachromosomal element functions, Other].	3.15452e-07
NZ_CP042840.1\|WP_147607156.1\|45689_45827_+\|hypothetical-protein	gnl\|CDD\|234907	PRK01130, PRK01130, putative N-acetylmannosamine-6-phosphate 2-epimerase.	1.79413e-06
NZ_CP042840.1\|WP_002318298.1\|42921_43239_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	0.000109706
NZ_CP042840.1\|WP_002338747.1\|35409_36081_-\|class-A-sortase	gnl\|CDD\|320680	cd06165, Sortase_A, Sortase domain found in class A sortases. Class A sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Firmicutes). They perform a housekeeping role in the cell as members of this group are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is cleaved at a conserved cell wall-sorting signal (Class A sortases recognize a canonical LPXTG motif, X can be any amino acid), and covalently linked to peptidoglycan for display on the bacterial surface. The prototypical sortase A protein from Staphylococcus aureus (named Sa-SrtA) cleaves the amide bond between threonine and glycine residues of the canonical LPXTG motif in a wide range of protein substrates with diverse functions that can promote bacterial adhesion, nutrient acquisition, host cell invasion, and immune evasion. Next, it catalyzes a transpeptidation reaction by which the proteins are covalently linked to the peptidoglycan precursor lipid II. SrtA is therefore affects the ability of a pathogen to establish successful infection. SrtA contains an N-terminal hydrophobic segment, a linker region and an extra-cellular C-terminal catalytic domain. The hydrophobic segment functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring. The catalytic domain contains the catalytic TLXTC signature sequence where X is usually a valine, isoleucine or a threonine. The gene encoding SrtA is generally not located in the same gene cluster as its substrates while the gene encoding SrtB is usually clustered in the same locus as its substrate.	2.36832e-45
NZ_CP042840.1\|WP_143162214.1\|43702_44389_+\|IS6-like-element-IS1216-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.2915e-91
NZ_CP042840.1\|WP_002354485.1\|47824_48511_+\|IS6-like-element-IS1216-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.80773e-92

>NZ_CP042840.1|WP_002322486.1|38180_38513_-|hypothetical-protein
MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYIIQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTAKGMGRLIS
>NZ_CP042840.1|WP_002311521.1|37220_37562_-|DUF5406-domain-containing-protein
MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLALNEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSVEIIEFVADKEE
>NZ_CP042840.1|WP_002311523.1|36911_37202_-|hypothetical-protein
MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCLHELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIIDEQKSCVLSIDSTLV
>NZ_CP042840.1|WP_002311524.1|36486_36720_-|hypothetical-protein
MARPVLDAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEKERLRKEFDYWREHNGIKDLKPARPVIRRKKLKK
>NZ_CP042840.1|WP_002338747.1|35409_36081_-|class-A-sortase
MKKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVDQINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFKGANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSNDGVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVVQGELQ
>NZ_CP042840.1|WP_002293487.1|32614_33367_-|class-C-sortase
MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQQIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGITEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIEEVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEENKKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK
>NZ_CP042840.1|WP_002293488.1|31837_32599_-|hypothetical-protein
MRNRKWLFVCAAALFTFTAYTQLTVADSQESTDSTEQTIQTSDSSAIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGVNGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQTGVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD
>NZ_CP042840.1|WP_002293489.1|31564_31825_-|hypothetical-protein
MKLIKLLLFNLSCLTAVFLYCGLLFSQLSILPSYQLYLMRILNIPAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG
>NZ_CP042840.1|WP_002345834.1|29477_31568_-|isopeptide-forming-domain-containing-fimbrial-protein
MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNPIQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYPSFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLLDNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDGSPVQFSGDTFISFNSLNPAGGKSTDLKGEYTHYDKMNTTDWYVRKDTVLSEFKSFYNNLNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQTWFTLSSATIFSVVPDQPEKTGVDKNGNNVNDNMLQVGDTIQYRIKQKVNRLGVDLLAVYDRFELIDNLPKEVDYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMKYNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNGKDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLTYKEVSAQVIDKSKGKDITSEGTLTYDSNLRTLKWEASADFLSNNLLDGREIQLIFTAKTPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLLLVLATFSYAVLRYI
>NZ_CP042840.1|WP_142966042.1|28986_29451_-|hypothetical-protein
MKKLIIVVTSLIAMIVILVGCSNEKNRQTNQDNGVLKSGTMWKEEVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFINKSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE
>NZ_CP042840.1|WP_002348857.1|41728_41923_+|hypothetical-protein
MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCKNKIKKVFHYISSSPCQIRPG
>NZ_CP042840.1|WP_002318299.1|42666_42921_+|AbrB-family-transcriptional-regulator
MGKELKVRKIGNSVGVILPSSLGLKSGDTVQAKQEGNLFILDTTQIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE
>NZ_CP042840.1|WP_002318298.1|42921_43239_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKALELTKNFPTIHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMKLGF
>NZ_CP042840.1|WP_143162214.1|43702_44389_+|IS6-like-element-IS1216-family-transposase
MTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMKAIRGLYKKTRKEGTLFGFSICTEIKVLLGIPA
>NZ_CP042840.1|WP_099119708.1|44785_44842_-|LsbB-family-leaderless-bacteriocin
MAWFKNKHGYYPWEIPRC
>NZ_CP042840.1|WP_002318791.1|44908_45250_-|bacteriocin-immunity-protein
MIDIREIKKIIHELYNSLMKRDKTKAILDITDVLLQVYKKIDSEKYPEILINKLVNYIYIVGFDNKIHFLGNDEKLLIELGDISKKAGINSKYKANFTDKSQFYSYSEKVPIR
>NZ_CP042840.1|WP_002313088.1|45250_45466_-|bacteriocin
MKKKLVKGSVICSMIGIGFIVIGTNVEAATYYGNGVYCNKQKCWVNWGQAWSKGVKRWGDNLFGSFSGGRI
>NZ_CP042840.1|WP_147607156.1|45689_45827_+|hypothetical-protein
MKIFKSTRRNETDAYQAGVDFIGKTLSGYTKLKFKFSRAFLSRRL
>NZ_CP042840.1|WP_000222573.1|45908_46868_+|IS30-family-transposase
MTYTHLTTDELVMIESYFKINQSVAKTAHCLNRSRQTIHKVYLFFKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI
>NZ_CP042840.1|WP_002354485.1|47824_48511_+|IS6-like-element-IS1216-family-transposase
MTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP011282	Enterococcus faecium strain E39 plasmid p1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP025426	Enterococcus faecium strain SC4 plasmid p1, complete sequence	221216-221254	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	LT603679	Enterococcus faecium isolate Ef_DMG1500501 genome assembly, plasmid: 2	452-490	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP018832	Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence	244126-244164	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040369	Enterococcus faecium strain VB3240 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP043485	Enterococcus faecium strain DMEA02 plasmid pDMEA1, complete sequence	27883-27921	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP020485	Enterococcus faecium strain CFSAN059070 plasmid unnamed1, complete sequence	96547-96585	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP041262	Enterococcus faecium strain VVEswe-R plasmid pVVEswe-R1, complete sequence	454-492	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP012385	Enterococcus durans strain KLDS 6.0930 plasmid unnamed 1, complete sequence	95092-95130	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP013995	Enterococcus faecium strain 6E6 plasmid unnamed1, complete sequence	358205-358243	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP014450	Enterococcus faecium strain ATCC 700221 plasmid unnamed1, complete sequence	119937-119975	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP018073	Enterococcus faecium strain VRE001 plasmid unnamed3, complete sequence	111370-111408	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP027518	Enterococcus faecium strain AUSMDU00004024 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP027498	Enterococcus faecium strain AUSMDU00004167 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP027507	Enterococcus faecium strain AUSMDU00004055 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP027502	Enterococcus faecium strain AUSMDU00004142 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135298	Enterococcus faecium isolate E7429 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135288	Enterococcus faecium isolate E7199 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135333	Enterococcus faecium isolate E7471 plasmid 3	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135340	Enterococcus faecium isolate E7356 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP046076	Enterococcus faecium strain VRE plasmid p5_03A17012, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	MT074686	Enterococcus faecium strain E1077 plasmid pE1077-217, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP025756	Enterococcus faecium strain AALTL plasmid pEFA-99d7, complete sequence	126934-126972	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP027513	Enterococcus faecium strain AUSMDU00004028 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135244	Enterococcus faecium isolate E6988 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135279	Enterococcus faecium isolate E6975 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135783	Enterococcus faecium isolate E4239 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135294	Enterococcus faecium isolate E7237 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135255	Enterococcus faecium isolate E7098 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135236	Enterococcus faecium isolate E7067 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135198	Enterococcus faecium isolate E6055 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135259	Enterococcus faecium isolate E4457 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135182	Enterococcus faecium isolate E1774 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040905	Enterococcus faecium strain N56454 plasmid unnamed, complete sequence	153621-153659	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP041256	Enterococcus faecium strain 515 plasmid p26, complete sequence	129212-129250	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP019209	Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence	71269-71307	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP019989	Enterococcus faecium isolate 2014-VREF-63 plasmid p63-1, complete sequence	249118-249156	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP017798	Enterococcus faecium strain E243 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135429	Enterococcus faecium isolate E8927 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135436	Enterococcus faecium isolate E8691 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135483	Enterococcus faecium isolate E4456 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135476	Enterococcus faecium isolate E8423 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135204	Enterococcus faecium isolate E7171 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135180	Enterococcus faecium isolate E0595 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135227	Enterococcus faecium isolate E7025 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135489	Enterococcus faecium isolate E8414 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135365	Enterococcus faecium isolate E8195 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135220	Enterococcus faecium isolate E7040 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135415	Enterococcus faecium isolate E8328 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135395	Enterococcus faecium isolate E8290 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NC_021987	Enterococcus faecium Aus0085 plasmid p1, complete sequence	107198-107236	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135345	Enterococcus faecium isolate E8202 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135325	Enterococcus faecium isolate E7654 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135358	Enterococcus faecium isolate E7948 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135409	Enterococcus faecium isolate E8284 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135352	Enterococcus faecium isolate E8014 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP050649	Enterococcus faecium strain BIOPOP-3 ALE plasmid pBIOPOP-3_ALE	91402-91440	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP050651	Enterococcus faecium strain BIOPOP-3 WT plasmid pBIOPOP-3_WT	102426-102464	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135385	Enterococcus faecium isolate E7933 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP044265	Enterococcus faecium strain V1836 plasmid pHVH-V1836-1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135318	Enterococcus faecium isolate E7663 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR134106	Enterococcus faecium isolate E6043 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135373	Enterococcus faecium isolate E8172 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP006031	Enterococcus faecium T110 plasmid pEFT110, complete sequence	1397-1435	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP011829	Enterococcus faecium strain UW8175 plasmid unnamed1, complete sequence	60362-60400	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR132068	Enterococcus faecium isolate E0139 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_AP019395	Enterococcus faecium strain QU 50 plasmid pQL50, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LN999988	Enterococcus faecium isolate EFE11651 plasmid II, complete sequence	97677-97715	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP033042	Enterococcus faecium strain Enterococcus faecium JE1 plasmid unnamed, complete sequence	52637-52675	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP025687	Enterococcus faecium strain CBA7134 plasmid pCBA710401, complete sequence	102651-102689	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040741	Enterococcus faecium strain VRE1 plasmid pVRE1-1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP014530	Enterococcus faecium strain E745 plasmid pl1, complete sequence	200630-200668	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023424	Enterococcus faecium strain K60-39 plasmid pTT39_p1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_AP022342	Enterococcus faecium strain KUHS13 plasmid pKO1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040877	Enterococcus faecium strain HB-1 plasmid punnamed, complete sequence	56543-56581	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP032307	Enterococcus faecium strain HY07 plasmid unnamed2, complete sequence	65333-65371	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040704	Enterococcus faecium strain HOU503 plasmid p1, complete sequence	67328-67366	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP044275	Enterococcus faecium strain V2937 plasmid pHVH-V2937-1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP017793	Enterococcus faecium strain E240 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP019993	Enterococcus faecium isolate 2014-VREF-268 plasmid p268-1, complete sequence	14572-14610	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP035655	Enterococcus faecium strain UAMSEF_08 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023790	Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023800	Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP035137	Enterococcus faecium strain SRCM103341 plasmid unnamed1, complete sequence	178898-178936	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP035661	Enterococcus faecium strain UAMSEF_09 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP035667	Enterococcus faecium strain UAMSEF_20 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NC_017963	Enterococcus faecium DO plasmid 3, complete sequence	33082-33120	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP035649	Enterococcus faecium strain UAMSEF_01 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040850	Enterococcus faecium strain F17E0263 plasmid p_unnamned1, complete sequence	105709-105747	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP042840	Enterococcus sp. DA9 plasmid unnamed4	39887-39925	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135171	Enterococcus faecium isolate E4227 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135192	Enterococcus faecium isolate E4438 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP041271	Enterococcus faecium strain VVEswe-S plasmid pVVEswe-S1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP037956	Enterococcus hirae strain CQP3-9 plasmid pCQP3-9_1, complete sequence	35165-35203	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135308	Enterococcus faecium isolate E7240 plasmid 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP040237	Enterococcus faecium strain VB3025 plasmid unnamed1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP018066	Enterococcus faecium strain E1 plasmid pE1_230, complete sequence	225612-225650	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023809	Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP033207	Enterococcus faecium strain RBWH1 plasmid pRBWH1.1, complete sequence	92046-92084	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP018129	Enterococcus faecium strain A_020709_82 plasmid unnamed1, complete sequence	17089-17127	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023805	Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP035221	Enterococcus faecium strain SRCM103470 plasmid unnamed1	86167-86205	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_AP019409	Enterococcus faecium strain SMVRE20 plasmid pSMVRE20L, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NC_020208	Enterococcus faecium ATCC 8459 = NRRL B-2354 plasmid pNB2354_1, complete sequence	61653-61691	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP034948	Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence	5084-5122	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP016164	Enterococcus faecium strain ISMMS_VRE_11 plasmid ISMMS_VRE11_p1, complete sequence	177278-177316	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP018827	Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence	244126-244164	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	LR135186	Enterococcus faecium isolate E4413 genome assembly, plasmid: 2	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP012461	Enterococcus faecium strain ISMMS_VRE_7 plasmid ISMMS_VRE7_p1, complete sequence	192113-192151	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023795	Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_MG674581	Enterococcus faecium strain HL1 plasmid pHLSA, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP023781	Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence	453-491	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LT598664	Enterococcus faecium isolate Ef_aus00233 plasmid 2	168263-168301	0	1.0
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP027401	Enterococcus faecium strain FDAARGOS_323 plasmid unnamed, complete sequence	109448-109486	1	0.974
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR135175	Enterococcus faecium isolate E4402 plasmid 2	453-491	1	0.974
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_LR134096	Enterococcus faecium isolate E1334 plasmid 2	453-491	1	0.974
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP042833	Enterococcus faecium strain FA3 plasmid unnamed1	47629-47667	1	0.974
NZ_CP042840_1	1.2\|39887\|39\|NZ_CP042840\|CRISPRCasFinder	39887-39925	39	NZ_CP012367	Enterococcus durans strain KLDS 6.0933 plasmid unnamed 1, complete sequence	3358-3396	4	0.897

1. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP011282 (Enterococcus faecium strain E39 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

2. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP025426 (Enterococcus faecium strain SC4 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

3. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to LT603679 (Enterococcus faecium isolate Ef_DMG1500501 genome assembly, plasmid: 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

4. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP018832 (Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

5. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040369 (Enterococcus faecium strain VB3240 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

6. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP043485 (Enterococcus faecium strain DMEA02 plasmid pDMEA1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

7. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP020485 (Enterococcus faecium strain CFSAN059070 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

8. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP041262 (Enterococcus faecium strain VVEswe-R plasmid pVVEswe-R1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

9. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP012385 (Enterococcus durans strain KLDS 6.0930 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

10. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP013995 (Enterococcus faecium strain 6E6 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

11. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP014450 (Enterococcus faecium strain ATCC 700221 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

12. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP018073 (Enterococcus faecium strain VRE001 plasmid unnamed3, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

13. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP027518 (Enterococcus faecium strain AUSMDU00004024 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

14. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP027498 (Enterococcus faecium strain AUSMDU00004167 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

15. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP027507 (Enterococcus faecium strain AUSMDU00004055 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

16. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP027502 (Enterococcus faecium strain AUSMDU00004142 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

17. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135298 (Enterococcus faecium isolate E7429 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

18. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135288 (Enterococcus faecium isolate E7199 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

19. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135333 (Enterococcus faecium isolate E7471 plasmid 3) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

20. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135340 (Enterococcus faecium isolate E7356 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

21. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP046076 (Enterococcus faecium strain VRE plasmid p5_03A17012, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

22. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to MT074686 (Enterococcus faecium strain E1077 plasmid pE1077-217, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

23. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP025756 (Enterococcus faecium strain AALTL plasmid pEFA-99d7, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

24. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP027513 (Enterococcus faecium strain AUSMDU00004028 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

25. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135244 (Enterococcus faecium isolate E6988 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

26. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135279 (Enterococcus faecium isolate E6975 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

27. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135783 (Enterococcus faecium isolate E4239 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

28. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135294 (Enterococcus faecium isolate E7237 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

29. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135255 (Enterococcus faecium isolate E7098 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

30. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135236 (Enterococcus faecium isolate E7067 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

31. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135198 (Enterococcus faecium isolate E6055 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

32. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135259 (Enterococcus faecium isolate E4457 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

33. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135182 (Enterococcus faecium isolate E1774 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

34. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040905 (Enterococcus faecium strain N56454 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

35. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP041256 (Enterococcus faecium strain 515 plasmid p26, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

36. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP019209 (Enterococcus faecium strain 2014-VREF-41 plasmid p41-1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

37. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP019989 (Enterococcus faecium isolate 2014-VREF-63 plasmid p63-1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

38. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP017798 (Enterococcus faecium strain E243 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

39. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135429 (Enterococcus faecium isolate E8927 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

40. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135436 (Enterococcus faecium isolate E8691 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

41. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135483 (Enterococcus faecium isolate E4456 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

42. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135476 (Enterococcus faecium isolate E8423 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

43. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135204 (Enterococcus faecium isolate E7171 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

44. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135180 (Enterococcus faecium isolate E0595 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

45. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135227 (Enterococcus faecium isolate E7025 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

46. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135489 (Enterococcus faecium isolate E8414 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

47. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135365 (Enterococcus faecium isolate E8195 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

48. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135220 (Enterococcus faecium isolate E7040 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

49. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135415 (Enterococcus faecium isolate E8328 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

50. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135395 (Enterococcus faecium isolate E8290 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

51. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NC_021987 (Enterococcus faecium Aus0085 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

52. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135345 (Enterococcus faecium isolate E8202 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

53. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135325 (Enterococcus faecium isolate E7654 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

54. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135358 (Enterococcus faecium isolate E7948 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

55. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135409 (Enterococcus faecium isolate E8284 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

56. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135352 (Enterococcus faecium isolate E8014 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

57. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP050649 (Enterococcus faecium strain BIOPOP-3 ALE plasmid pBIOPOP-3_ALE) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

58. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP050651 (Enterococcus faecium strain BIOPOP-3 WT plasmid pBIOPOP-3_WT) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

59. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135385 (Enterococcus faecium isolate E7933 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

60. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP044265 (Enterococcus faecium strain V1836 plasmid pHVH-V1836-1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

61. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135318 (Enterococcus faecium isolate E7663 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

62. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR134106 (Enterococcus faecium isolate E6043 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

63. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135373 (Enterococcus faecium isolate E8172 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

64. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP006031 (Enterococcus faecium T110 plasmid pEFT110, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

65. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP011829 (Enterococcus faecium strain UW8175 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

66. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR132068 (Enterococcus faecium isolate E0139 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

67. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_AP019395 (Enterococcus faecium strain QU 50 plasmid pQL50, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

68. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LN999988 (Enterococcus faecium isolate EFE11651 plasmid II, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

69. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP033042 (Enterococcus faecium strain Enterococcus faecium JE1 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

70. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP025687 (Enterococcus faecium strain CBA7134 plasmid pCBA710401, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

71. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040741 (Enterococcus faecium strain VRE1 plasmid pVRE1-1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

72. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP014530 (Enterococcus faecium strain E745 plasmid pl1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

73. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023424 (Enterococcus faecium strain K60-39 plasmid pTT39_p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

74. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_AP022342 (Enterococcus faecium strain KUHS13 plasmid pKO1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

75. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040877 (Enterococcus faecium strain HB-1 plasmid punnamed, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

76. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP032307 (Enterococcus faecium strain HY07 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

77. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040704 (Enterococcus faecium strain HOU503 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

78. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP044275 (Enterococcus faecium strain V2937 plasmid pHVH-V2937-1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

79. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP017793 (Enterococcus faecium strain E240 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

80. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP019993 (Enterococcus faecium isolate 2014-VREF-268 plasmid p268-1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

81. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP035655 (Enterococcus faecium strain UAMSEF_08 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

82. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023790 (Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

83. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023800 (Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

84. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP035137 (Enterococcus faecium strain SRCM103341 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

85. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP035661 (Enterococcus faecium strain UAMSEF_09 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

86. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP035667 (Enterococcus faecium strain UAMSEF_20 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

87. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NC_017963 (Enterococcus faecium DO plasmid 3, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

88. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP035649 (Enterococcus faecium strain UAMSEF_01 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

89. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040850 (Enterococcus faecium strain F17E0263 plasmid p_unnamned1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

90. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP042840 (Enterococcus sp. DA9 plasmid unnamed4) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

91. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135171 (Enterococcus faecium isolate E4227 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

92. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135192 (Enterococcus faecium isolate E4438 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

93. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP041271 (Enterococcus faecium strain VVEswe-S plasmid pVVEswe-S1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

94. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP037956 (Enterococcus hirae strain CQP3-9 plasmid pCQP3-9_1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

95. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135308 (Enterococcus faecium isolate E7240 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

96. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP040237 (Enterococcus faecium strain VB3025 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

97. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP018066 (Enterococcus faecium strain E1 plasmid pE1_230, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

98. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023809 (Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

99. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP033207 (Enterococcus faecium strain RBWH1 plasmid pRBWH1.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

100. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP018129 (Enterococcus faecium strain A_020709_82 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

101. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023805 (Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

102. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP035221 (Enterococcus faecium strain SRCM103470 plasmid unnamed1) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

103. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_AP019409 (Enterococcus faecium strain SMVRE20 plasmid pSMVRE20L, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

104. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NC_020208 (Enterococcus faecium ATCC 8459 = NRRL B-2354 plasmid pNB2354_1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

105. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP034948 (Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

106. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP016164 (Enterococcus faecium strain ISMMS_VRE_11 plasmid ISMMS_VRE11_p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

107. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP018827 (Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

108. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to LR135186 (Enterococcus faecium isolate E4413 genome assembly, plasmid: 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

109. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP012461 (Enterococcus faecium strain ISMMS_VRE_7 plasmid ISMMS_VRE7_p1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

110. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023795 (Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

111. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_MG674581 (Enterococcus faecium strain HL1 plasmid pHLSA, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

112. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP023781 (Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

113. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LT598664 (Enterococcus faecium isolate Ef_aus00233 plasmid 2) position: , mismatch: 0, identity: 1.0

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgagggtg	Protospacer
***************************************

114. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP027401 (Enterococcus faecium strain FDAARGOS_323 plasmid unnamed, complete sequence) position: , mismatch: 1, identity: 0.974

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgcctgatttttcgtcgagggtg	Protospacer
******************.********************

115. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR135175 (Enterococcus faecium isolate E4402 plasmid 2) position: , mismatch: 1, identity: 0.974

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgcctgatttttcgtcgagggtg	Protospacer
******************.********************

116. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_LR134096 (Enterococcus faecium isolate E1334 plasmid 2) position: , mismatch: 1, identity: 0.974

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgcctgatttttcgtcgagggtg	Protospacer
******************.********************

117. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP042833 (Enterococcus faecium strain FA3 plasmid unnamed1) position: , mismatch: 1, identity: 0.974

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
gccccaagggattcagcgtctgatttttcgtcgaggatg	Protospacer
************************************.**

118. spacer 1.2|39887|39|NZ_CP042840|CRISPRCasFinder matches to NZ_CP012367 (Enterococcus durans strain KLDS 6.0933 plasmid unnamed 1, complete sequence) position: , mismatch: 4, identity: 0.897

gccccaagggattcagcgtctgatttttcgtcgagggtg	CRISPR spacer
agccccaaggattcagcgtctgatttttcgtcgagggtg	Protospacer
. *** *.*******************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

43702 : 63118

Streptococcus_phage(25.0%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_143162214.1\|43702_44389_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.0e-126	98.7
WP_099119708.1\|44785_44842_-\|bacteriocin	LsbB family leaderless bacteriocin	NA	NA	NA	NA
WP_002318791.1\|44908_45250_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_002313088.1\|45250_45466_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_147607156.1\|45689_45827_+	hypothetical protein	NA	NA	NA	NA
WP_000222573.1\|45908_46868_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-32	36.1
WP_002354485.1\|47824_48511_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_147607144.1\|49151_50183_+	hypothetical protein	NA	NA	NA	NA
WP_147607145.1\|50331_50946_+	hypothetical protein	H8ZJH4	Ostreococcus_tauri_virus	5.1e-05	61.3
WP_142432546.1\|51459_52365_+	hypothetical protein	NA	NA	NA	NA
WP_142432547.1\|52448_53231_+	hypothetical protein	NA	NA	NA	NA
WP_147607157.1\|53674_55561_+	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	2.4e-77	33.4
WP_147607146.1\|55573_58477_+	type III restriction-modification system endonuclease	Q71TG1	Escherichia_phage	8.1e-93	29.3
WP_147607147.1\|58466_59738_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_147607148.1\|59727_61590_+	DEAD/DEAH box helicase family protein	I3VYY6	Thermoanaerobacterium_phage	3.7e-22	24.2
WP_002323245.1\|61945_63118_-\|transposase	IS256-like element IS1542 family transposase	A0A0N9STL0	Staphylococcus_phage	1.3e-121	88.8

DBSCAN-SWA_2

66738 : 131092

Streptococcus_phage(47.83%)

transposase,integrase

attL 67944:67971|attR 98743:98770

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_147607149.1\|66738_67917_+\|transposase	IS256-like element ISEf1 family transposase	A0A220NQR7	Corynebacterium_phage	4.0e-30	25.3
67944:67971	attL	NA	NA	NA	NA
WP_002292150.1\|68695_69268_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	3.9e-23	42.6
WP_002292156.1\|69412_70117_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_073438625.1\|70143_70434_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_002292161.1\|70580_70814_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_002319350.1\|71011_72916_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.8e-99	35.3
WP_002319351.1\|73603_74221_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_002307628.1\|74458_75010_+\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	2.9e-31	41.7
WP_121686712.1\|75128_75815_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	6.5e-126	98.7
WP_002292678.1\|76022_76352_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_002300557.1\|76341_76629_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002292680.1\|76914_77772_+	ParA family protein	F0PIG8	Enterococcus_phage	8.1e-33	30.7
WP_002292681.1\|77772_78321_+	hypothetical protein	NA	NA	NA	NA
WP_147607150.1\|79485_80166_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.6e-108	83.6
WP_002375441.1\|80949_84177_+	VWA domain-containing protein	NA	NA	NA	NA
WP_002375439.1\|84178_84910_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002375438.1\|84974_86462_+	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_002375436.1\|86548_87745_+	class C sortase	NA	NA	NA	NA
WP_002375434.1\|87741_88863_+	class C sortase	NA	NA	NA	NA
WP_002314385.1\|88986_89674_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.9e-126	99.1
WP_104885939.1\|89704_89974_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_104885615.1\|90315_92244_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.8e-96	36.4
WP_104885614.1\|92500_93064_+	recombinase family protein	A0A219Y9V9	Aeromonas_phage	3.2e-38	47.5
WP_104885613.1\|93258_93546_-	hypothetical protein	NA	NA	NA	NA
WP_104885612.1\|93535_93865_-	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_002339771.1\|95344_96382_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002335374.1\|96407_97346_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_147607151.1\|97526_98717_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.6e-23	27.1
WP_002292150.1\|99249_99822_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	3.9e-23	42.6
98743:98770	attR	NA	NA	NA	NA
WP_025481494.1\|99966_100671_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_002320187.1\|100898_101237_+	hypothetical protein	NA	NA	NA	NA
WP_002292161.1\|102223_102457_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_016628643.1\|102654_104559_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.1e-101	35.8
WP_002329962.1\|104828_105065_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	7.6e-18	73.8
WP_002329961.1\|105061_105271_-	hypothetical protein	NA	NA	NA	NA
WP_002341318.1\|105578_105941_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	8.4e-16	43.6
WP_002341317.1\|105957_106575_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_002354485.1\|106709_107396_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_002329956.1\|108178_108676_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002329955.1\|108696_109515_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_002329954.1\|109511_110342_+	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_016629115.1\|110518_113044_+	AAA family ATPase	NA	NA	NA	NA
WP_144169094.1\|113131_113437_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_147607152.1\|113556_114243_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	7.7e-127	99.1
WP_094889737.1\|114729_115856_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.3e-74	53.7
WP_010731429.1\|116071_117847_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_002405179.1\|117877_118480_+	hypothetical protein	NA	NA	NA	NA
WP_033918032.1\|119664_121260_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.5e-125	50.9
WP_094889738.1\|121249_122461_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	9.1e-14	33.7
WP_049142574.1\|122474_125624_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.1e-21	23.1
WP_142432376.1\|125714_126401_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	4.2e-125	98.2
WP_002344897.1\|126529_126886_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002344896.1\|126875_127142_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002344895.1\|127300_128302_+	DUF4062 domain-containing protein	NA	NA	NA	NA
WP_008271463.1\|129525_129771_+	hypothetical protein	NA	NA	NA	NA
WP_002311006.1\|129868_130090_+	hypothetical protein	NA	NA	NA	NA
WP_002319817.1\|130411_131092_+\|transposase	IS6-like element ISS1N family transposase	A0A1X9I6C6	Streptococcus_phage	2.5e-109	84.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042839

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP042838

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP042840

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection