CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042827	Ruania sp. HY168 plasmid unnamed, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_CP042828	Ruania sp. HY168 chromosome, complete genome	15 crisprs	csa3,WYL,cas3,DEDDh,DinG	1	11	1	0

1. NZ_CP042828

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042828_1

• CRISPR_ID: NZ_CP042828_1
• CRISPR_location: 268858-269066
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP042828_1

Consensus_repeat	Method
CCGCTTCCGCTGAAGCGCCGGAG	CRISPRCasFinder

spacers of NZ_CP042828_1

>1.1|268881|16|NZ_CP042828|CRISPRCasFinder
TCGACAGGTACGGACG
>1.2|268920|25|NZ_CP042828|CRISPRCasFinder
GACCAGAAGAACGAGCAGGCCGATA
>1.3|268968|28|NZ_CP042828|CRISPRCasFinder
GCCGATGCGGTGACCGAGGGCTCGAGCA
>1.4|269019|25|NZ_CP042828|CRISPRCasFinder
GGTTCCGCTACCAGCGCCACCGATG

CRISPR arrays and Neighbor proteins around NZ_CP042828_1

CRISPR arrays

The CRISPR arrays of NZ_CP042828_1

>merge|NZ_CP042828|1|268858-269066|CRISPRCasFinder
CCGAGTCCGCTCCAGCGGCCGAATCGACAGGTACGGACGCCGCTTCCGCTGAAGCGCCGGAGGACCAGAAGAACGAGCAGGCCGATACCGCTTCCGCTGAAGCGCCGGAAGCCGATGCGGTGACCGAGGGCTCGAGCACCGCTTCCGCTGAAGCAGGTGAGGGTTCCGCTACCAGCGCCACCGATGACGCTTCCGCTGAAGCGTCCGAG

>NZ_CP042828|1|1|268858-269066|CRISPRCasFinder
CCGAGTCCGCTCCAGCGGCCGAA	TCGACAGGTACGGACG
CCGCTTCCGCTGAAGCGCCGGAG	GACCAGAAGAACGAGCAGGCCGATA
CCGCTTCCGCTGAAGCGCCGGAA	GCCGATGCGGTGACCGAGGGCTCGAGCA
CCGCTTCCGCTGAAGCAGGTGAG	GGTTCCGCTACCAGCGCCACCGATG
ACGCTTCCGCTGAAGCGTCCGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147919259.1|281430_282231_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213186
NZ_CP042828.1|WP_147915457.1|284555_285422_-|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|119324
NZ_CP042828.1|WP_147919258.1|280726_281431_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213191
NZ_CP042828.1|WP_147915443.1|257516_258365_-|DUF1524-domain-containing-protein	unknown	unknown	gnl|CDD|377857
NZ_CP042828.1|WP_168211602.1|262056_263970_-|response-regulator	unknown	unknown	gnl|CDD|225107
NZ_CP042828.1|WP_147915446.1|260751_261798_-|DUF2183-domain-containing-protein	unknown	unknown	gnl|CDD|227187
NZ_CP042828.1|WP_147915441.1|251005_253306_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl|CDD|235367
NZ_CP042828.1|WP_147919257.1|271183_271423_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147919256.1|267680_268592_+|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl|CDD|376563
NZ_CP042828.1|WP_147915454.1|280189_280702_-|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|225168
NZ_CP042828.1|WP_147915449.1|266547_267543_+|DUF2804-family-protein	unknown	unknown	gnl|CDD|378522
NZ_CP042828.1|WP_147915442.1|253667_257414_-|TM0106-family-RecB-like-putative-nuclease	unknown	unknown	gnl|CDD|225160
NZ_CP042828.1|WP_147915453.1|275208_280023_-|NAD-glutamate-dehydrogenase	unknown	unknown	gnl|CDD|377452
NZ_CP042828.1|WP_147915455.1|282227_283553_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380555
NZ_CP042828.1|WP_147915444.1|258864_259947_+|rubrerythrin-family-protein	unknown	unknown	gnl|CDD|153124
NZ_CP042828.1|WP_147915456.1|283557_284559_-|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|119323
NZ_CP042828.1|WP_147915445.1|260071_260635_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147915452.1|274584_275115_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147915448.1|264157_266425_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223354
NZ_CP042828.1|WP_147915451.1|271621_274327_+|family-78-glycoside-hydrolase-catalytic-domain	unknown	unknown	gnl|CDD|379971

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147919259.1|281430_282231_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	2.92608e-93
NZ_CP042828.1|WP_147915457.1|284555_285422_-|branched-chain-amino-acid-ABC-transporter-permease	gnl|CDD|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	2.73635e-59
NZ_CP042828.1|WP_147919258.1|280726_281431_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	1.93493e-99
NZ_CP042828.1|WP_147915443.1|257516_258365_-|DUF1524-domain-containing-protein	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	1.52275e-17
NZ_CP042828.1|WP_168211602.1|262056_263970_-|response-regulator	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.52686e-61
NZ_CP042828.1|WP_147915446.1|260751_261798_-|DUF2183-domain-containing-protein	gnl|CDD|227187	COG4850, COG4850, Uncharacterized conserved protein [Function unknown].	3.52188e-72
NZ_CP042828.1|WP_147915441.1|251005_253306_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl|CDD|235367	PRK05222, PRK05222, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional.	0
NZ_CP042828.1|WP_147915455.1|282227_283553_-|ABC-transporter-substrate-binding-protein	gnl|CDD|380555	cd06332, PBP1_aromatic_compounds-like, type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes. This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.	4.93793e-112
NZ_CP042828.1|WP_147915454.1|280189_280702_-|DoxX-family-membrane-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	4.94485e-11
NZ_CP042828.1|WP_147915449.1|266547_267543_+|DUF2804-family-protein	gnl|CDD|378522	pfam10974, DUF2804, Protein of unknown function (DUF2804). This is a family of proteins with unknown function.	1.04741e-102
NZ_CP042828.1|WP_147915442.1|253667_257414_-|TM0106-family-RecB-like-putative-nuclease	gnl|CDD|225160	COG2251, COG2251, Predicted nuclease (RecB family) [General function prediction only].	1.43325e-71
NZ_CP042828.1|WP_147915453.1|275208_280023_-|NAD-glutamate-dehydrogenase	gnl|CDD|377452	pfam05088, Bac_GDH, Bacterial NAD-glutamate dehydrogenase. This family consists of several bacterial proteins which are closely related to NAD-glutamate dehydrogenase found in Streptomyces clavuligerus. Glutamate dehydrogenases (GDHs) are a broadly distributed group of enzymes that catalyze the reversible oxidative deamination of glutamate to ketoglutarate and ammonia.	0
NZ_CP042828.1|WP_147915456.1|283557_284559_-|branched-chain-amino-acid-ABC-transporter-permease	gnl|CDD|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	1.19851e-66
NZ_CP042828.1|WP_147915444.1|258864_259947_+|rubrerythrin-family-protein	gnl|CDD|153124	cd02433, Nodulin-21_like_2, Nodulin-21 and CCC1-related protein family. Nodulin-21_like_2: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter. .	5.85359e-78
NZ_CP042828.1|WP_147919256.1|267680_268592_+|cation-diffusion-facilitator-family-transporter	gnl|CDD|376563	pfam01545, Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.	1.31017e-23
NZ_CP042828.1|WP_147915448.1|264157_266425_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.57753e-38
NZ_CP042828.1|WP_147915451.1|271621_274327_+|family-78-glycoside-hydrolase-catalytic-domain	gnl|CDD|379971	pfam17389, Bac_rhamnosid6H, Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.	5.65036e-133

Protein sequences

>NZ_CP042828.1|WP_147919256.1|267680_268592_+|cation-diffusion-facilitator-family-transporter
MSLTVILAFAANLLIAIAKTVAGVITGAASMVAEAAHSWADSGNEVFLMIAERRAARAPDRDHPAGYGREAYVWSMMAAIGLFVAGAAVSIMHGVQELLDPEPASNFVVAYLVFAVAFVLEGISFLQAFRQMRAEARASGRDLIDQAVATSDPTLRAVFAEDFAAVVGILIATAGVLAHDLTGSPIPDAVGSILVGLLLAVVAVVLVGRNRDFLVGQVLQPAKRALVIDGLRQHAEIDRLTMLHVEYVGPRKVLLVAQVDLVGDAPEHELGERLRRLERELESKPAVIRAILSPAASDEADLT
>NZ_CP042828.1|WP_147915449.1|266547_267543_+|DUF2804-family-protein
MPDQRELTEPVSLTLPGGRFNPGAAGWARQPIVDTTGIGRGRGRNKRWEYWGVVTPAHLIGLTISHIDYAAVHELWVLDRATEQTWSQSATVIPARGVQLPAVCEGGPSRGSAKDLALAIDEVDGGTRLRAIAPGVRLDLRAARPAGHERLAVVVPWSSTRFQYTVKDVARPASGRLWLDGVEHRLPEGSWAVLDHGRGRWPHDIEWNWGAGSGVSGGRVIGLQVGGKWTEGTGSTENAVLVDGRLHKLHGELDWDYDLTDWRRPWRVSGRGLAAEFVPFYNKRSHTDFLVLSSRTDQCFGHWSGQVDLGDGERVVFSGLAGWAEEVHNRW
>NZ_CP042828.1|WP_147915448.1|264157_266425_-|LLM-class-flavin-dependent-oxidoreductase
MTDYGHDLQFGTFLTPQNADPHVPVQLAQLTEAAGLDLVTFQDHPYQPAFLDTWTLISWVAAQTERVTIAGNVLNLPLRQPAVLARSVASLDRLSAGRIALGLGAGGFWDAIEAMGGPRRSPGEAVQALTEALAIIRGLWDSTERRPFRLAGEHYQVSGAKRGPAPAHDVPIWLGAYKPRMLRLTGREADGWLPSLGYMKDGDLARGNTIIDEAAEEAGRHPAQVRRLLNVGGAITESRGAMLQGPVAQWVDELTAFALEDGIGTFILSGDDPQLIQTFGEEIAPAVREAVAAERTARGTTAAATRRGRGALELRRPGIDYEAVPASLAASAVEPGDRGYAGVRHNYLRSGSPGLVLLPRSTEEVVEALGYAREQDVPLGVRSGGHGISGRSTNDGGIVLDLRALDEVRLADAGERRVRLGAGATWEKVAHTLTDHELAISSGDYGGVGVGGLATTGGVGLLGRQYGLTIDHVLAADVVLADGSVARASAEENPDLLWALRGAGGNFGVVTSVEVAAMPLRRVVYSQMILDATDTAGLLERWGELVQTSPRELTSFLILSPNRGSQGPVAQLMTVLATEDTDAAVPMLERLAGAGDLLDHRAYLLPYAQVLQAAERQHSGGGDPAVRSALVEHLDADVSGAFARVAASPAAYFLQVRATGGAAGDLASEATAYPHRRQNFLLTAMSSNQQRIDAVWDAEMTEHADGLYLSFDTDTRPERLTDAFGANLPRLRELKARFDPENLFRANFPIPPAQT
>NZ_CP042828.1|WP_168211602.1|262056_263970_-|response-regulator
MIHLADLWQRLRATPRRRAVADALAVLIVGLLVLLLGFGTMITSDSAWIEPPVWWHVGLLVIGCVLMVVKIDAPVATLIGGAVLFAADVAIGGSIGVMLVLVDLIFTVALVGSATALRRLIGAIAIAITILTALGWAALGGPRGAVFLGLQSFAVLGTPLWWGRSVRQQRELTELAEMRAQDQLRLAEMRQEEVLRDEREQMARDLHDAIAGHLSAIALRTEAALVRRPAPADTETLSNIRAFSLDALTEMRTMIELLRGTTPERAPSRFSDAEARERLVGDHGGTIDCPDLPELSTEVDQAAYRILQESLTNATKHGGPPVAVTVTTAEQHVQIEVRNAVALAVPDADGGARLDRPSHPGSGLGLVIMGERARAAGGDLEAGPHDGRWLVRARLPAPPPLPAQASRKAESMSVRVLLAEDHAAVRAGLRLILESDPDVEVVGEAGDGQAAVTNARALRPDVVLMDIQMPRLNGVEATTEIVAEELAQVLVLTTFDLDEYVFAALRAGAAGFLLKSTGAAELIAAVHRVATGDGVVAPEVTRRLLAAFASSRPGAVESTTSPNGASAHEAGGPLASLTDREHDVLVLIARGCSNQEIAATLVITEATTKTHVSRVLAKLDCSSRVQAAILAREAGIQ
>NZ_CP042828.1|WP_147915446.1|260751_261798_-|DUF2183-domain-containing-protein
MSATHVAARVEDGFHRRLIPFLRKRGWRPRIISYIGYGNSDSVRVLGRVVLSRQQRSQDAGGKASLQEDLIARRGWRSYVTAPVSYLPVSVQVGGASHRTVTDRSGYIDLTVGDHGLDPGWHDVQISAKAAATISARVRIVSTDAQLGIVSDIDDTTLVTLVPRPLVALWNTFVRHGTARHVVPGMASMYSRILTDHPGAPLFYLSTGAWNVMPTLVQFLRSHGFPAGPMLLTDWGPTNTGWFRSGQEHKRVALRRLAAEFPHIRWVLVGDDGQHDPQLYREFAREYPNRVAAIAIRELTPGEQVLAHGTPVPTVQPGEERQFTPAPEMSGADGFDLAPQVRRALGSA
>NZ_CP042828.1|WP_147915445.1|260071_260635_+|hypothetical-protein
MTDQRTDERRVGVNEGSKAWAEEAVEVLTEVAGHYLGIITYAELAEEVQARTRLRTRAPFRNWIGGVLATVVSRCHALGLPPLTSLVVHGRGKDGGTEEGTVHARFTCYRRFADDIPAEVLAAAAAADRAKAEEAAASTRASRAKSRASARTRAPRERRQKATEEAPKICPSCFVQLPGSGICDDCG
>NZ_CP042828.1|WP_147915444.1|258864_259947_+|rubrerythrin-family-protein
MPSDASVDQPRPAEIRRWRRYLAEERAEAAVYTQLATRRDGEERAILLELARAEGRHAAHWEALLGEHAGRPRPPALRSRLLIALARRFGSVFVLALAQRAESRSDYAEDDHATAAMAADEQIHEEVVRSLAVRGRARISGTFRAAVFGMNDGLVSNLALVMGIGASGVSTGTVLLTGLAGLLAGALSMGAGEFVSVRSQRELLEASTPSVTAHQAVGDLDVNANELALVYRARGMSAEEAQARAEERLATHNPTIAPQHAAAHSLEEIGSPWQAALSSFGFFSSGAIIPVLPYLLGLTGWAAVGLASGLVGVALMVTGAIVGILSGAAPLPRALRQLAIGWGAAAATYLLGLAFGATLA
>NZ_CP042828.1|WP_147915443.1|257516_258365_-|DUF1524-domain-containing-protein
MRERQPVRRLTTAVVLGALLLAVALLLPQWWQHVRAAPPWPVPAASLERARAALPRLPVVAPRGLADYDREFFGRPWADVDGNGCDTRNDVLRAWLRDTRLDPVADCVVVTGQLTDPYTGHLVEFRRGPQTSAAVQIDHVVALADAWRKGAAEWPADLALQFANDPANLIPVDGQVNQDKQADDAASWLPPDAGFHCAYVVQQVLVKDAYGLGVSAEELGAIGEVLSGCDAAEPGITGGSGAGVDPAIGGNFRDRRQGRRPSDPEACLRWHGTGGSRSAAGR
>NZ_CP042828.1|WP_147915442.1|253667_257414_-|TM0106-family-RecB-like-putative-nuclease
MFLQDDTLVYSASDLTLARDCEFALLSKLDEKLGRRPRLRVENAMRDYSARLGDEHEAQVLADYRQRFGTGVVEIAVPEDYTAATLRAHAERTRRALRSGADVVFQGGFFDGRFHGRSDFLVRQVSAQGQVSYAVVDTKLARSVKPGAVLQLAAYADQLLAAGIEVAPETVLHLGDGTIATQDMAGSVAVYREHRAHVQAMLDAGRAADGPVVWGDDRYQACLWCDYCQEAVAANRDVKLVWGMRGSHRTALRAAGITTIEELADAPRPAPKVHPKMWRRLQAQAKLQLRQERAEAAGTQPQVFAEVHGLAALQAMPAPDPGDVFFDFEGDPLWVDSDRTVWGIEYLFGLLQADGEQEYVSFWAHDRAAEGQALRDFLDYLHRRREQFPDMHVYHYAAYETATLRRLAERHQVGVEEVEELIAAGVFIDLYATVKHSVRVSQRSYSIKKLEPLYMGSELRNADGVTSGGDSVLAYAQAQALRDAGDVAGFEARLAELAEYNRYDCLSTLRLRDWLITQREAALAEQGAAGPSGAGRDGAAAADQPPSAAFVAAMTGAEFQPSGDWSGQVEETPEQQERRRLAEALHRHVPEPLGPLLAAALEYHRQEDDPYWREHFDRLRSDRGVSDTRDVLEVFHTRRRTVANEYGRTRTLLDLAGRFGTGSTVEPGGQVFVVYDAPLPAGLTPPAGCDRAAIRAKVVSRDVSPTGLDRVTLSESVPPEAGELTADPVLVTPGPPPPARALVQAIELVARGELAAHGITDGDGERDAAGAGASAADGDPGASGGDPPNPTAPSAADREATGARVGAAALDIAAGIPPRLRGEQPLPPRAGTDADGTAGAVVSALTATDDSYLAVQGPPGTGKTYLGVQVIARLVQELGWRVGVVAQSHAVVEHVLHGLVDAGLPTEQIGKRARVPRTEDLAALGIVEAEEPPWVTLETYGHHGFLARHAEHGAVVGGTAWDFANRRRFDAGELDLLVIDEAGQFALANTFAVATAARRLLLLGDPQQLPQVSQGSHAAPVDESALGRLAHGHATLPSTHGYLLEQTRRLHPALCSPVSELYYDGQLHSHPVAAERHLDGLDAGLHVVTLDHTHRTVDSPEESAEAITQLESLLDRSWTNGQTRPLAPADVLVVAAYNAQVQRLRHDLAAAGLPEVRVGTVDKFQGQQAAVVLISLATSSAESTPRGLEFLLSPNRLNVAISRGQWAAILVRSRALTRYLPWEAGELRELGGFIELCRRAQPRRPRHH
>NZ_CP042828.1|WP_147915441.1|251005_253306_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MSQPLPTATILGYPRIGPNRELKRALEAYWAGRSSAEELRTASAAVRRGTRTRLTELGLDPATAAIPSDFAHYDQVLTTALQVGAVPARFGIEPTGTPLGLDEEFRLARGDAETPPLELTKWFDSNYHYLVPEISPTTGLRHIPGSQAVTEFGEALADGVLTRPVLVGPVTFLLLAKPENPGDPAPLERLDDLLAVYIDWLAELAGAGATWVQLDEPALVADTWEVPAEQVTAAAERAYRVLAGSAARPSLLVAAPYGELRERFGVLARTGVEAIGIDLVRGSVPDGLEIAAEHGAGVLAGVVDGHNVWRTDLDRAAATVGVVAARVGQVSVGTSTSLLHVPHTTAVESALSEQLRSWLAFADEKVTEVLTLARAQAGEDVTGEFAAARSALAARAQADGVRRAQVRDRVAAVTAADIHRADYADRVEAQRTLGLPVLPTTTIGSFPQTTQLRQARARLRTGQLDAAGYEQVIRAEIAAVIRLQEELGLDVLVHGEPERNDMVQYFAEHLDGFDVTQHGWVQSYGSRCTRPSLLWGDVSRPAPITPAWSGYAASLTEKPVKGMLTGPVTILAWSFVRDDLPLAEVASQVALALRDEVADLEAAGIRIVQVDEPALRELLPLRREDQRAYVDWSVAAFRLATGGAAAGTQVHTHLCYSEFGEVIDAIDGLDADVTSIEAARSAMEVVPELAAARFGRGLGPGVWDIHSPRVPSVEEVAGQLRLADGGLQRGQLWANPDCGLKTRGYSETTAALTNLVAAARQVRAER
>NZ_CP042828.1|WP_147919257.1|271183_271423_-|hypothetical-protein
MGVGGGIFLIVVGAILSFAVRDSWDVVDLTMVGYICMGAGALTVILALVINAQRARTHHINTVEHRPPPETGDPRDRGY
>NZ_CP042828.1|WP_147915451.1|271621_274327_+|family-78-glycoside-hydrolase-catalytic-domain
MLSAVNGAPHGLRLERIADATCLGTATPLLSWVTPPHKDDQQAVEVQWVDAAPGSAERSWRIETAASVFVPWPGDPLRSGQRGQVRIRTEHDGVVSPWSDPVRVHVAPLGPDDWTGRFITPARGGGLDDPAPVLTAAVTVGEDLVHARLLLSALGAVRMRMNGHRVGADVLTPGWTSYAHRVRFHGYDVTDLLTAGSNDLQATLGNGWYRGALTSTLRRDLYGPELALLVQLELSYADGRTEVIGSDETWRAHTGPVRADDLYGGQHTDLRRREPDGPGDAVHPLEVDLNRLVGPEGPPPRVTERIPARSITPRGQGRHLADFGQNVVGWVHLAGVPADSGTGTGTGAGAGAGTGTAAGTGTGTAAGETPGTSPATPDQGAATTQTPSAVVQVRHAEVLADGELCTRPLRQAAATDTYELPSGRSDLSPEFTVHGFRYAEITGVEELTAEQVTAEVVGSDLRRIGWFGCSEPLLNQLHENIVWSARGNFLDVPTDCPQRDERLGWTGDIHVFARTASFLYDVDGFLASWLQDLAADQHGDGGVPVVIPDVFRDGNTLATAWADAAVVVPWVLYERFGDHDVLARQLPSMRAWVDRMAAELDEDGLWTTGEQYGDWLDPTAPPDDPFASAADTHVVQQAHLVRSAVLVGHALRRLGHGALADHYEDLADTARAAFQTHYVTGAGIVRSDCQTVYALAIRFKLLATAEQQRFAGERLAELVREAGGTVRTGFVGTPVVLDALAQAGHANLAQEMLLTTECPSWLYPVTMGATTIWERWDSMLPDGTVNPGEMTSFNHYALGAVGDFLHRRIAGLAPLGPGYRVVEVNPIIDGPITSAWATHESPYGTVRVAWERDDDGVTHLEVDLPAGVTARVFPPSNRAGAPKGRSRGAVTVGAGTHTFTG
>NZ_CP042828.1|WP_147915452.1|274584_275115_+|hypothetical-protein
MKWPRGIAMIPPSIRASLAQGETALADVQVTTFAQGSAIGGKPRPGVGMDWSPLVGGLTVNDRWFGGALAGYSAGGEHGSIAAGFARVLEDLGHARLLLTTHRVALYPSGQWDSTRVLLAFSIDRRALTEVGVAPRLFQHGRLRLQFADGSWAMAMAGVLLPIAARRFARIYRESR
>NZ_CP042828.1|WP_147915453.1|275208_280023_-|NAD-glutamate-dehydrogenase
MNASTPRQREEIMGAVARLVGDDQGDLAARLLEHVATEDLVERSPEVMAGLVAAMGDLAQRREAEQTLVRVFNPETVEHGWTTPHTIVQVCTDDMPFLVDSVTAAISGAQHLVDLVIHPQVAVRRGSDGTLEEVLPDPARTEAGTVESWMAFAVDRMSERSRAYLTERLEKVLADVRDAVADWIPMRQRCEEIARELDAHTPATVDRAEIEPTERFLTWLAQNNFTFLGYREYRLDTMNGDDVLRPVPGSGMGILRHAPDGDDIFARLRPEARRSAREPHLLTVTKANSRATVHRPVYLDYIGIRSFDANGNVVGERRFLGMFTTAAYAESVLRLPIVSEKVSAVLERSGFSPHSHSGKDLLGILEDYPRDELFQADVETLAAVTESVQHLAERRRSKLFLRRDEFGRFVSCLVYLPRDRYNTTVRLRIEEMLREEFGAEQVDYTTRVSESPLAQVHFVLRMPRESSIPDVDVDRLQVQLAAAARTWEEDLLDALHDQPGEDAGMRFARGFPEAYKEDFDAAAAVTDLAQLVGLTGNESRVQLYTPSSDSPAQRRVKVYRAAPLILTDVLPMFTDLGVDVLDERPYTITDEADGDKHVYDFGLLLRGGRDWPDDDASRAFEEALLAVREGRAESDQLGELVLSAGLTWREVVVLRTIARYLRQVGSTFSVEYLESALVANPQTAARIVALFQARFDPDHPAGADAEARGHAQEEIRAAVYADLEQVSSLDQDRIIRSFVGVIDATLRTNYFQPDADGASHAHVSLKLDCARVPGLPAPVPMAEIWVYSPQVEGVHLRFGAVARGGLRWSDRREDFRTEVLGLVKAQMVKNAVIVPTGSKGGFVAKQLPDPAVDRDAWLAEGKASYTAFIRGMLDITDNRVGPQVVPPQRVVRHDGDDPYLVVAADKGTAAFSDLANSISAEYGYWLHDAFASGGSAGYDHKEMGITARGAWESTKRHFREMGRNSQTEDFTVVGIGDMSGDVFGNGMLLSEHIRLVAAFDHRHVFLDPNPDAASSYAERRRMFDLPRSTWADYDTSLLSEGGGVYPRTAKSVPISAQVREALGLGEGPGDLSPAELIHACLQAPVDLLYNGGIGTYIKASTESDDDIGDRANDAIRVDGAQLRCQVVVEGGNLGASQLGRIEAAQRGVKINTDAIDNSAGVASSDREVNLKILFTSLIKDGALSLDERNELLVSMTDEVAAQVLRDNYVQNVLLGNSRAQAHAMLGVHQRLIHWLEERGDLDRELEFLPSDTEIADRDAAGEGLTQPEFAVLVAYAKLALKADLESTTIADGDWFHTTLMQYFPEVLRERFAEQIEEHPLRREIIVNTVVNSMVNRGGITFAYRASDETGASSEQVARAYVTGREIFDLSSYTQDVEALDNKVPAAVQTSLYLDFRRLLDRCSRWFVLHRPDGVEVAREVAAFAEPVRRLVGQLPQFLQGEERERCATHADDLVEAGLGHELAERAATLIPALGLLDVVELSRETGENLQSVASLYYATSEHFGFDNLLIRVAALPLDDRWDALARAAARDDLYATLADLTRTVQRATDADLPATERLAAWEDAAGAALTRVRSSLPSEADLNAADGLAPLSVAVRGLRSLVRR
>NZ_CP042828.1|WP_147915454.1|280189_280702_-|DoxX-family-membrane-protein
MDTGILILRLVLAAVLLAHATQKSVGWFGGNGLTKQAEIFASLGLRPGRAMVLVASASELSAATLLTLGLLTPLGALAAAGTMTVAGLTMQLAAGKFWNVAGGGEYPYLIAVVAVALGITGPGGYSLDAAIGGPLFGFAADPPAWVGAVIVVSAAAAAVPFAALIRRNRT
>NZ_CP042828.1|WP_147919258.1|280726_281431_-|ATP-binding-cassette-domain-containing-protein
MLDVSGLHVGYATSRVLNGVDLQVAAGETVGLLGRNGMGKTTLVRALCRLEPPTITAGAVSLEGTDLLRLRTHEVSHHGIAMVPQGRRVFGSLTVEENLRIVRGASADEPWTPARVFSFFPRLAERARSFARTLSGGEAQMLAIGRALMLNPRLLIMDEPSEGLAPAVLDTIEDRLQELRTTGLSVLVAEQNVDLALALSDRVYILGEHGTVAWTGTANELDRSPELLGVHLGL
>NZ_CP042828.1|WP_147919259.1|281430_282231_-|ATP-binding-cassette-domain-containing-protein
MSAATAAGPPPPGPAPRKVAAALELTGLTKSFGALTVVDHVSVTVPVGGRLAVIGPNGAGKTTLFRMIAGELPVSSGSVALFGDDVTRVSERGRAIRGVSRTFQVSNLFPSLSAVDNVRLAAQVNTATARTFWRRTAPDDTYGDHAREALEQVGLGGRASDSVSDLSHGEQRQLEIAMALVSRPRLLLFDEPAAGLSQSERMMLQSLLQQLPADLSYVLIEHDMSLALELTDQVLCLDNGRPLAYGSPAEIRADAQVQAVYLGRRP
>NZ_CP042828.1|WP_147915455.1|282227_283553_-|ABC-transporter-substrate-binding-protein
MRVINRSRPRAATAAAALAVLAVVAAGCAPSESLAQNDDPDASAGSEGPGEDPAASDAEPFTVGLLVSSTGFAANMGSYMQQGWDLYWEENGSTVGGFEVRTIVEDDASNPETALTKAQRLVTEEDVDVVVGPILANNGLAVADYLDQQGVANIAQTAADDLTQRERNPHVLRVGALAGSQATFPGGQWAHDEGHRTAATICPDYAFGWENCGGFVSAFTDAGGEVVDQLWYPATATDMSTYVTELIGSGADVVFAGTSGGNDGANFIRAGNDFDLFNQIPVLLNCCGADQTVLSDMGESAVGLHSVSYFAAGSDSPGTAAFTEAYLQQYSGIPSVYAAASYTAAEVLAEVLAEASAAPTGEDLVTAMREVTLEDSAMGSISFDEYNNMVGPVFIREVELREDGALWNTVNETFEGVSQFWTYDPEEYLDNPPFSQSVTGQ
>NZ_CP042828.1|WP_147915456.1|283557_284559_-|branched-chain-amino-acid-ABC-transporter-permease
MRRATAIKLGSILAALVLAFTLPYVLPSYYVSLVTLVLTAALLAMAVNLLAGQAGLVSMGHAGIAAAAGYGVAWSSRAGHSLATQLLLALGLTLLTSVIYGLISMRTKGIYFLMVTLAAGMVCYGVAFRWSSVTGGDNGLTGIRRPAAVAEYWQYYFLVLLMFVLTLLALMLVSRSPFGLVLRGVKDSDSRLRSLGYNIAAYKFTAIVLSGLVAGLAGVLTVWNTEFISPDSAGVVRSALAVVMIVLGGLGTTLGPLVGAGIVVAIEHILSSYVERWQLILGLLFILAVIFAPSGLVGSLRRRRQRDRTPPVPDEEAAHPADPHVLSSNHPER
>NZ_CP042828.1|WP_147915457.1|284555_285422_-|branched-chain-amino-acid-ABC-transporter-permease
MDLIALAQQTLNGLSFGALLFLMASGFTLVFGLMRIANLAHGAFYLVGAYVAVFTVGLTGSFWIGVLAGTAATAATGLVTETGLLRRIRGQEMPEVLLTVGVLFVLSDLLLMSFEGGPMALPAARGAPSGALVIGSFAYPWYRLFVIGVTIIVGIALFLLQRYSTVGAIVRAGVDDRETAAAMGINIDRVFTGVFVVGAVLAGLAGAIGAGMLSLSPDTGIDILLFAMVVVIIGGLGSIKGAVIGAILIGLIDTFAKVWIPELSYFTIFAPMALVLVLRPAGLFGRVA

Crispr_ID: NZ_CP042828_2

• CRISPR_ID: NZ_CP042828_2
• CRISPR_location: 934685-934761
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_2

Consensus_repeat	Method
TCGCTGTGCCCGACCCGCGGTTC	CRISPRCasFinder

spacers of NZ_CP042828_2

>2.1|934708|31|NZ_CP042828|CRISPRCasFinder
ACCGACCGCGCCGACGGCTCCAGTGGGGTGG

CRISPR arrays and Neighbor proteins around NZ_CP042828_2

CRISPR arrays

The CRISPR arrays of NZ_CP042828_2

>merge|NZ_CP042828|2|934685-934761|CRISPRCasFinder
TCGCTGTGCCCGACCCGCGGTTCACCGACCGCGCCGACGGCTCCAGTGGGGTGGTGGCTGTGCCCGACCCGCGGTTC

>NZ_CP042828|2|2|934685-934761|CRISPRCasFinder
TCGCTGTGCCCGACCCGCGGTTC	ACCGACCGCGCCGACGGCTCCAGTGGGGTGG
TGGCTGTGCCCGACCCGCGGTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147915947.1|944946_945405_+|SRPBCC-domain-containing-protein	unknown	unknown	gnl|CDD|176856
NZ_CP042828.1|WP_147915946.1|944323_944950_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378968
NZ_CP042828.1|WP_147915936.1|928995_930336_+|hypothetical-protein	unknown	unknown	gnl|CDD|227284
NZ_CP042828.1|WP_147915941.1|938108_939317_+|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NZ_CP042828.1|WP_147915935.1|927978_928977_+|hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240644
NZ_CP042828.1|WP_147915932.1|923329_924208_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223472
NZ_CP042828.1|WP_147915949.1|946562_948038_+|NlpC/P60-family-protein	unknown	unknown	gnl|CDD|366353
NZ_CP042828.1|WP_147915942.1|939333_940035_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|371689
NZ_CP042828.1|WP_147915945.1|942553_943906_-|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	unknown	unknown	gnl|CDD|236105
NZ_CP042828.1|WP_168211643.1|932763_933507_+|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|179028
NZ_CP042828.1|WP_147915931.1|920695_923239_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147915944.1|941318_942557_-|homoserine-O-acetyltransferase	unknown	unknown	gnl|CDD|234678
NZ_CP042828.1|WP_147915938.1|931221_932496_-|N-acylglucosamine-2-epimerase	unknown	unknown	gnl|CDD|238153
NZ_CP042828.1|WP_147915933.1|925200_926457_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270303
NZ_CP042828.1|WP_147915937.1|930332_931289_+|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl|CDD|223489
NZ_CP042828.1|WP_147915934.1|926734_927730_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224525
NZ_CP042828.1|WP_147919312.1|924204_924969_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224096
NZ_CP042828.1|WP_147919313.1|935057_938054_+|FAD-binding-protein	unknown	unknown	gnl|CDD|223354
NZ_CP042828.1|WP_147915948.1|945466_946273_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235975
NZ_CP042828.1|WP_147915943.1|940044_941127_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147915947.1|944946_945405_+|SRPBCC-domain-containing-protein	gnl|CDD|176856	cd07814, SRPBCC_CalC_Aha1-like, Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Micromonospora echinospora CalC, human Aha1, and related proteins. Proteins in this group belong to the SRPBCC domain superfamily of proteins, which bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. MeCalC confers resistance to the enediyne, calicheamicin gamma 1 (CLM), by a self sacrificing mechanism which results in inactivation of both CalC and the highly reactive diradical enediyne species. MeCalC can also inactivate two other enediynes, shishijimicin and namenamicin. A crucial Gly of the MeCalC CLM resistance mechanism is not conserved in this subgroup. This family also includes the C-terminal, Bet v1-like domain of Aha1, one of several co-chaperones, which regulate the dimeric chaperone Hsp90. Aha1 promotes dimerization of the N-terminal domains of Hsp90, and stimulates its low intrinsic ATPase activity, and may regulate the dwell time of Hsp90 with client proteins. Aha1 can act as either a positive or negative regulator of chaperone-dependent activation, depending on the client protein, but the mechanisms by which these opposing functions are achieved are unclear. Aha1 is upregulated in a number of tumor lines co-incident with the activation of several signaling kinases.	4.58526e-20
NZ_CP042828.1|WP_147915946.1|944323_944950_+|helix-turn-helix-domain-containing-protein	gnl|CDD|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	1.46751e-10
NZ_CP042828.1|WP_147915936.1|928995_930336_+|hypothetical-protein	gnl|CDD|227284	COG4948, COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only].	1.88986e-15
NZ_CP042828.1|WP_147915941.1|938108_939317_+|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	1.59976e-06
NZ_CP042828.1|WP_147915935.1|927978_928977_+|hydroxyacid-dehydrogenase	gnl|CDD|240644	cd12167, 2-Hacid_dh_8, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.27585e-103
NZ_CP042828.1|WP_147915932.1|923329_924208_-|ABC-transporter-permease-subunit	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	9.0382e-82
NZ_CP042828.1|WP_147915949.1|946562_948038_+|NlpC/P60-family-protein	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.39432e-30
NZ_CP042828.1|WP_147915942.1|939333_940035_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|371689	pfam11716, MDMPI_N, Mycothiol maleylpyruvate isomerase N-terminal domain.	2.43439e-10
NZ_CP042828.1|WP_147915945.1|942553_943906_-|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	gnl|CDD|236105	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated.	0
NZ_CP042828.1|WP_168211643.1|932763_933507_+|glucosamine-6-phosphate-deaminase	gnl|CDD|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	1.63805e-63
NZ_CP042828.1|WP_147915944.1|941318_942557_-|homoserine-O-acetyltransferase	gnl|CDD|234678	PRK00175, metX, homoserine O-acetyltransferase; Provisional.	0
NZ_CP042828.1|WP_147915938.1|931221_932496_-|N-acylglucosamine-2-epimerase	gnl|CDD|238153	cd00249, AGE, AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases.	9.67568e-33
NZ_CP042828.1|WP_147915933.1|925200_926457_-|extracellular-solute-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.19515e-63
NZ_CP042828.1|WP_147915937.1|930332_931289_+|prolyl-oligopeptidase-family-serine-peptidase	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	2.82735e-06
NZ_CP042828.1|WP_147915934.1|926734_927730_+|substrate-binding-domain-containing-protein	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.91747e-72
NZ_CP042828.1|WP_147919312.1|924204_924969_-|ABC-transporter-permease-subunit	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.90723e-79
NZ_CP042828.1|WP_147919313.1|935057_938054_+|FAD-binding-protein	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	3.48012e-77
NZ_CP042828.1|WP_147915948.1|945466_946273_+|SDR-family-oxidoreductase	gnl|CDD|235975	PRK07231, FabG-like, SDR family oxidoreductase.	3.12574e-31
NZ_CP042828.1|WP_147915943.1|940044_941127_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.73882e-57

Protein sequences

>NZ_CP042828.1|WP_168211643.1|932763_933507_+|glucosamine-6-phosphate-deaminase
MGATVAEVADAAAARAAEGILAAIHARGSARVLFASAPSQEAMIARLGSDSRIDWSLVRSFHLDEYVGLSAAAPQSFGQWLEDRLPAAALPGFFRMHAEAEDGVPAEIERYGALIEESPIDVTCLGIGVNGHIAFNEPGVSHLADSALARRVDLDLASRQQQVDEGLFATLADVPTSALTLTVPAVTGAGILVCTVLGEHKAAAVAQALEGPITRDCPGSLMQAHPAAFWFVDGAAAAQLTQRHVDR
>NZ_CP042828.1|WP_147915938.1|931221_932496_-|N-acylglucosamine-2-epimerase
MTFATRARAELEQVILPFWYELGIDHELGGFHTCFDNRGRDRTAETKFTWSQGRFVWLLAHAATLAERGLLTADADQLTQWAVRGAQFLTEHTIRPDGTTRYAVHRDGAPIEDGSAPERSVYADLFVVMGLAELAGRTGRPTDLAPARLVLDRASADIHAGTAPTPPYAVPEGRDALGPHMILLNALLVLAQAEQTLGVESSGTRQALAAEAAHVMSFRAADGTFVEMRRTEPRPPDVPETQVDRHRVPGHAIEAIWMVLAAGELLGTDDHRTSALESVPALCALAWDPEYEGLLRYTDAAGPTRPAGAAEPTPYLDGVLATWDTKLWWVHSEACATTAIAHRRYASEAARPWFERLWDYTLRTFPAGDQGREWIQIRDRQGNPKDEVVALPVKDPFHITRNLMQLVELGAELDSAGRAPHSAR
>NZ_CP042828.1|WP_147915937.1|930332_931289_+|prolyl-oligopeptidase-family-serine-peptidase
MIDIQDGNSRRLRQWWRDWLGAERDSHGTWTTRRRPDDPRGWQDSDLVLHSFGSDLGARLLRPTPSRPGERSPVVIVPFYETASLVGEPCARTAHRPPDRPTQAYAVELARRGLAALAVPWWFEVAAAHSPARNLSERYGPPAAAHAAAQDRTALGRSLGDLFLAVDALLDQDWVDPARIGVHGHSLGGKLALHLTALDERVAAGVAHEPGLGLQHSNWDAPWYLGAHQPAGRDHDELLGLVAPRPFLIGAGGDSDGDHNADLVQRATEWWPAGQGPEVLRHDGGHPLTEDVLAGTITWLSEALDRPSPAPPPAPPAA
>NZ_CP042828.1|WP_147915936.1|928995_930336_+|hypothetical-protein
MRACDVRVLAATVAFHAVQLDQPLSISGRAIAWFTMAEVELQVADRSGRRGSGRGATILSVPWAWPVAAIDIEDRDRALRELTEELAAATVASGPADPIEHWRVLYGDLDTRLHRLASRYGVAQVPRLAGLLALGAVDSAVHDAWAMTAGRPASTMYDAAHLGSDLGWFDPALAGRYPGEFLGRGRRRLPVQHVVGVSDPLTAAEAGAEARPLTDWLRTEGVHHLKVKVSGDRPEQDAQRVVDVARLGLAEAGQVAVAVDPNEGCADASAALHLVDEIDRIAPEVTPLLRYLEQPVPRDAPAEPEAMARLGDRLPVLLDEGFSDLSMLPQLRDQGWSGVVIKAAKGHSLALLTHAYARCHRLWVAVQDLTALSWALVHSARLVSTFELSAPHLEYNSRQYAPRAAQELLSTLPELAHVRDGQVHLPSSSGPGLYELPSSTTVNGAG
>NZ_CP042828.1|WP_147915935.1|927978_928977_+|hydroxyacid-dehydrogenase
MTDRRTYVAMRPEEFDRLFSPEAAAELGQLTQVDYASGEGKVPVPEDIAERYDVLITSWSTQRFPPEQLQGSRLRLVVHAAGSVRTLFPREVLDGQVQLAQGGADAMAVAVAELSVTLALVLLRNVHSHDRGLQGTRDWVTGGRGMLGRSVHDQRVGVVGLSRVGRQAARMMQGLGVTRLSAYDPYAAPESAPGIDLLPLDELCATSDVLLVCAPVTPETRGLLGAREFAALPDGAVLINAGRSAVTNEAALVAELRSGRISAGLDVFDTEPLPADSPLFGLDNVVLTPHVAGGTTWSRLEQGRAVVEEVGRFLRGQPLAHEVTAQNYDRLA
>NZ_CP042828.1|WP_147915934.1|926734_927730_+|substrate-binding-domain-containing-protein
MRRATIYSIAAELGISASTVSRAFSRPDLVRDSVRQRILDAADQIGYQPSRAARSVATGRTGLVGLLVPDITNPFVPPLVRAIEMAAAERQAGVLLVDARANGAAEPGLVVQLKAQVDGLVIVSPRASASALSGALGSTAAVVVNRVMRGMASVVCDNTVAIERAVQALVADGHETLALLRGPADAWASKRRAEAFRRAAADAGVRLLEHGPFEAQFEDGRAAAEAVAASEASAVLAFDDLMACGVIAGLTDAGLRVPYDVSVLGCDDVLLARTMTPALSTISAPIGGLGERAVELLDEVMAGARIRQERLEGALALRGTTAVARPRKSAA
>NZ_CP042828.1|WP_147915933.1|925200_926457_-|extracellular-solute-binding-protein
MKRTTGAKLTGMAAAAMMLVAACGGGDDGSGGEPANPEEVSGDVTFWFYPVGVSETTDWWEPHVAEFNEEYPNVNIELVPQSFSNREDAIVTAVAGQNAPDVIYFNPDFIPQWAEEDMLMPLDDLREDWDDFYDSALEANTWEDTLYGAPLLMQMMTSYCNTEALEAAEVECPTNWDEFREAAPKFVDAGYYATEYSGTSTLNHTFYMFLWQAGGQVLSEDMTTAAFNSPEGLEALELIQEMTENEWVPQQPLTVMEPFEQTAVGQGEVGYVMGGNLTQTRELVDPEIIEVVPPLQNVEQVAGGSVGAWSIFNTTENPDAARAWVRFLSEEDFMRDFLADTGYLPPRESIDDLFEDDPQTAQGMDYLDQVRVGIMHPQARQIIDTIRPHIQSVLVNGNDPQAALDTAEQEVNALLERG
>NZ_CP042828.1|WP_147919312.1|924204_924969_-|ABC-transporter-permease-subunit
MMLSLGDYKLNGTFELLGLDNFERLFADPIFWNALRATGVYAFVAIPLTVAISLAMAQLCNRVLRGMSFYRSIFFLPVVTSPVLSGLVFVWIFSPDGPLNWVLDGVGIGGVNWLQSSFWVLPSLALVSAWMNFGYNMLILLAGMLAIPIDYYEAASLDGANSWQRFRNVTMPLLKPALFFVLVLETVKSFQVFDTIYVMTSGGPVRASYTLTYMIYDQGFGYFDFGYASAAGVVLLVITLIFSLIQRRLVGRSA
>NZ_CP042828.1|WP_147915932.1|923329_924208_-|ABC-transporter-permease-subunit
MTATSTAPSRPAGASAPISPVPAKRRKRTWRLHLLLIVAALLTAFPFYAMVALSLQPGEAVELPGSLLPTAPSFGAYAEAMGSRSIPTWALNSTIYSVVSVFLVLLFASMAGYAFAKKRFFGRELIFWVFVAMLMLPYHLTIIPQYLVVSELDGLNTMWGMILPTIANAQAMFLMRQFIQDIPDELIDAARIDGAGEFRIYWTIILPQTKPIMATLGTFVFLWHWNDFLWPLVSQQSPTNYVLTVGLSSMQEQEAPLATIMAGSVITFIPALLVFIVLQRYFVRGVMMSGIK
>NZ_CP042828.1|WP_147915931.1|920695_923239_+|hypothetical-protein
MSARPVHRPGASGLSRRGFVTGTLGAGLGASVWGTTALGSGPARAAEQAIGPVNGGFEEAVVDGVIPGWSQSYGGGGAGSLSVVETHAFEGQASLQIHDPDSDQAYGLLSDAMPVTAGEDYELTLRVRLPESTEPNDTIHGKAYLYFYAESGSRVGSSSAHFRDLPHGEWASVRLGATAPEQATTVSVLLYATPADSSTFYIDDVRLKHNPPLEITDLGVAMYTANVRLGRADVLPDGSAVAYVFNNGEPLSLNVVDLNSGEVLEVHEVSGSRVISTAAIGDDHMLYFSGRSPDPGALWRYDPFSREVEQLAAAPAGETAVNDLLVDGGTVYGSTYPNAKVWAYDTLTGDLRDYGQVTDLGSYARKMTMVDGDLWIGTSTSPELLRMDTETGERTELPLPPDMVGTADFFSELTTHEDLVLARYSPSDEASGAIYDLSAGEWYGQLDTGWWTYTTVDGAFFYAEANTVRAFDIATRQSRSIGWEDSALAEEYGGTARINVVDLSIDGFPGSTLVGFRDDGSIWRFNLQTAHGDILTPDIDGAPAKVQSVGHGADGNIYFGAYLSSGVISRIVVDTGELEQLSGPSQADSIVGHHNQTVVGTYPGAGFYAGHRNKTWQWGTNPSHLFSVGRDNGQDRAATMVAAGPRVAAGTIPNFGELGGALVLVNPNSGKYDIYRNIVPDQSVTALAYQDGIVYGGTGIYGGLDSEPTAETAELFAWDTRRDRLVTRNAVVAGAEIIHALAFDSVGRLWGMGDEGTLFQCDVRTLQAVRNLDTGIRNANIWGRLSELYQHPVDGLMYGNAGGRLFRFDPEQPDFTVLGPGGVRYSAVDAKGVIYFANDTNVFRWLP
>NZ_CP042828.1|WP_147919313.1|935057_938054_+|FAD-binding-protein
MFGGLATRTTGNRSRRAWHTARVSSVTGTDTATELTTALRSALEGEVDASSRRRAEYSTDASNYRVVPEVVVFPRSTQDVLTALEIARAHAVPVTARGGGTSIAGNSVGPGMILEFSRHLNQILEVDPEARTARVQPGVIMTDLQKAAAAHGLRFGPDPSSQARATMGGLIGNNACGPHAVAYGHTASQVISLEVVDGQGRRFTAGAGDLDPVPGLAELVQANLATIRTEFARFSRQLSGYSLEHLLPENGSDLAKFLVGTEGTLVTVLEATVRLVPLATSPVLLALGYPDMPSAADAVPAMLSHDVLAVEGLDAELVEVVRQHHGDHAVPDLPEGGGWLLIEVGGESPEHALEKAQAVAADAGTDAVQVIPAGPEAAAMWQIRADGAGLAGRTAAGAQAWPGWEDAAVPPENLGTYLREFQALMASHGVTGLPYGHFGDGCIHIRIDFPLADQAGADAFRMFMLDAAALVARHGGSLSGEHGDGRARGELLTAIYSPTAIGLFEQIKTLLDPAELLNPGVVVRPRPVDADLRRPHAKPLPLLTGSGFSFAHDGGDMTNAVHRCVGLGKCRADLPSSFMCPSYLATRDEKDSTRGRARVLQEMANGTLVQGWDAPEVHESLDLCLSCKACSSDCPAGVDMAQYKSEVLHRTYQGKRRPVSHYALGWLPRWARMITTVPALARLVNAVLGVRPIGKAVLAAGGMDTRRQMVSFAGESFHRWWRRRKDDPAGTVSRPAPGEQRRQEDDPAGTASEPPPGTGRRREVLLWADSFSAYLDTSGARAVVDVLEQAGYTVRVPESAACCGLTWISTGQLDGARSRLRQTMDVLSPYARAGIPIVGIEPSCTAVLRSDLVDLFPDDERARLLAEHTYTLAELLTGAEAPPDWQPRDLTGTTIIAQPHCHQHAVIGYQADLDLLRRAGAEVTTLTTCCGLAGNFGMEKGHYDVSVGVAEQSLLPTLRAAPDDAVYLADGFSCRTQASQLAGVEGLHLAELLRRAGA
>NZ_CP042828.1|WP_147915941.1|938108_939317_+|hypothetical-protein
MPSFAFESGYLVPASIGQPSTSPLSPDVRKALRDYLLDVIEADLFPIEWSGEDDPVLTAMDVAGQVVTAVVTDRLDGDRLLAALSRAGEATSTPWLTIAGRYPSGVAGFRRDWNAFRESRPPGAKPGPQLYVVAGEVSREVLEATRVLHGVQVFAVDARESVTGQQLLDVTAVQPATVRVLDGAVVHEIEPAITAASPRADEALSAPTPAADQALSAPTPVAALEETVSAAAPPPVARTAEEPPELQGAESRPVPDQSPGEASVPTPETATHPTVAPDLDAAAPAQQGSFPERARAAEPDPEPVSVDPQLRAVARLVGAPMPIELRHAGQVQHAVLTAEGALQVGEATVATIERATEILGGEPSHAWTSWHVAGFPMSEARAEATRAVAPVRASGRRRHRNR
>NZ_CP042828.1|WP_147915942.1|939333_940035_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MTSPAQIADELRDQWDLLRTRLEDTADTVLDEPSSLPGWSVRDLVAHLGLSLDLISRCELVAQDPEPLTFAGYLAACAEDAERISDRVLDYSAGLGRDVFDAVDEVADRALERLDELVAAGPKAMVRTSRGVISTADFLLTRLLELVVHTYDLAPVLVDPVPVDTGARHLVAEALVQIVADRAGYRLIVDDEEAWILAASGRIGWDEAVARGAVRPEYLSDGVPDLGANLPLL
>NZ_CP042828.1|WP_147915943.1|940044_941127_+|Gfo/Idh/MocA-family-oxidoreductase
MAQPVRRRCADSVARSDSLQQSTEERRDAVTLRWGLIGPGRIAAKVAADFPQVTNGRLEAVASRSRERAEAFATEHAALAGHPVRALEGYDALFADPEIDAVYIATPHSDHARQAIAAIEAGKAVLVEKSFAATLDGARSITEAAHAHQVFVMEAMWTRFQPAVQRAKALIADGAIGQVRAVAADLGVRREFDAEDRMFARELGGGALLDLGVYVVSFAQHILGAPDRVHATGSLLPETGVDAEAGILLGYADGRSATLQISFRLPLPGNARIYGTEGWIDIPPRFHHPDRVVLHRSGQEPVTEELPPPGAGYALEFIEVGECLQAGRQESATMPLADTLVVQAVLQQAADQLGVALEDR
>NZ_CP042828.1|WP_147915944.1|941318_942557_-|homoserine-O-acetyltransferase
MSPGATTVYPVTSRQIRSAGRIVRPTRPARRRHTPTKPIPASGAWREDLPVGNRQFVDLGPLPLEAGGQLPNVTLAYETWGELSPTGDNAILILHALTGDSHVVGDAEEGHASAGWWSSLVGPGLPLDTDRYFVVAPNVLGGCQGSTGPSSPAPNGTPWGSRFPYVTVRDQVAAELELADHLGVGAWQLVIGASMGGHRVLEWAVTAPERVAAIAAIATAAQTSADQIAWAHAQLGAIRADPQFRGGDYYDAADGDGPHVGLGIARQIAHTTYRSAHELDERFGRIPQGGENPLGGGGRFAVQSYLDHHADKLSRRFDANSYVALTESMLTHDLGRDRGGVEEALASISARTLALAVDTDRLFPPSQSRRIADGVSRGVYRELRSDHGHDGFLIENDQVGAILTEFLAAARS
>NZ_CP042828.1|WP_147915945.1|942553_943906_-|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase
MSNTWHFDTRQIHAGQAPDADTGSRAVPIHQTTSFVFKNTDEAGKRFALAELGPIYTRLNNPTNGVVEDRLASLEGGVGALVVASGQAAETLAILNVAEAGDHVVASPSLYGGTYNLLHYTLPKLGLSVSFVENPDDAASWRAAAQENTKLFFGETIPNPKGDVLDIEAVSAVAHEIGVPLIVDNTVATPYLVRPLEHGADVVVHSTTKYLGGHGTSIGGAIVDAGSFNYADYPEKFPNYNQPDPSYHGLVYARDLGEGGAFGVNLSFILKARVQLLRDLGPAASPFNSFLLLQGLETLSLRMERHVENAKKVAEWLEARSDVVKVNYAGLPSSPYFQLAQKYTPAGPGAVLAFEIAGGLEAGKAFVDGLELHSLVANIGDVRSLVIHPASTTHSQLTPEEQAASAVTPGLVRLSVGLEHIDDILADLETGFAAAAATSAQDAAGSTVGA
>NZ_CP042828.1|WP_147915946.1|944323_944950_+|helix-turn-helix-domain-containing-protein
MQDMQIVTDPKAAALLLDPVRRQLLAAAGEPASAAQLAQRVGLSRQKVNYHVRALEERGLLQQVEERRWGGITERLLVATAISYVVSPEALGEVRADPRKVTDRLSAQYLVALATRAVREVGELLRRAGAEGQQVATLSVDSVVRFRSAGERAQFADDLGAAVRSLVARYHAADAADGREHRLVIAVHPIPADSQSDTPVAVRGKEQS
>NZ_CP042828.1|WP_147915947.1|944946_945405_+|SRPBCC-domain-containing-protein
MNEQDAHTNARGIDLEIEVPGTPEQVWEAIATGAGVSAWMHPTQIEEHAGGSYSFDMQLGAGSNDTGRVADYDRPHRFATDGVVWQPQGDAPPATLATEWFIEARDGGSCTVRMVMSGFGTGDVWDEEIDGMTAGMGQALQALRSYLQAAVR
>NZ_CP042828.1|WP_147915948.1|945466_946273_+|SDR-family-oxidoreductase
MLLEDKVAVVYGAGGAVGSAVAQVLAREGAEVFLAGRTRVKLDRAAEAVEASGRRRAQVATVDALDEDDVGRHLDSVLNVAGRVDISVNAVGFDNGEQGIPLTDLTADDYCRPIAEYTRTHFVTAKAAGRQMVAQRRGVIIALSNPMAKAPAALSGCFGQYAAAVEGLATQLAAELGPDGVRSLCLRPTGMPASALEHDSAPGRMWRRAAERFGIGIDELLETIGGGTLSGEPVSTGDVAEAAAFVASDRAKGLTGTVINVTGGAVAD
>NZ_CP042828.1|WP_147915949.1|946562_948038_+|NlpC/P60-family-protein
MTRTKWRSAVAALAAGVLAGTLSAAPAQADPDYPSEDDIAQAEQAEQSTADRVRTIEVQLAANNAELEQTRVDAQVAAEAYNQASVALEQAQADADAAATDAEQADADVLAAQQQVAQIAMASYRNNGEVQQLSMFFSADDFEQALDRATMFEVLGSDADDAHQRLDAAERVAEVMHLRADETLADAEAAAQLREEASRDADAAALVAQNAVESTASERNSLITELASLRETTVELEDERQAGIEAEQRERENAAAAAALEAQAEQEAAEEAARAEAAEEQETARDRSTEDSQSSSSSSDDRSERPRNTDSGSSGSSGGNSSGSSSSGDSGSSGGSGSDSGSSSSGSSGGSSSDSGSGNSGSDSGGSTAPSSVGRTALNWAMTQIGKPYVWGADGPNSYDCSGLTMRAFQNAGVNLPRTTGAQYAATTHVPVGDMRPGDLIFYSSNGSASGIYHVAIYAGNGMRVHAPSPGSNVEHVQIWWTNVLPYAGRV

Crispr_ID: NZ_CP042828_3

• CRISPR_ID: NZ_CP042828_3
• CRISPR_location: 1631914-1632165
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP042828_3

Consensus_repeat	Method
AGGCNGCCNCGGANGCCC	CRT

spacers of NZ_CP042828_3

>3.1|1631932|21|NZ_CP042828|CRT
CAGCCGACGCTCCGGCTGCTG
>3.2|1631971|21|NZ_CP042828|CRT
CGGCCGCCGAAGCAGCTGCTG
>3.3|1632010|18|NZ_CP042828|CRT
CGGTTGAGGCTGCGACCG
>3.4|1632046|18|NZ_CP042828|CRT
CGGCTGAGGACGCGACTG
>3.5|1632082|30|NZ_CP042828|CRT
CGGCTGAGGCTGCCACGGAAGCTCCGGTTG
>3.6|1632130|18|NZ_CP042828|CRT
CGGCTGAGGCTGCGACCG

CRISPR arrays and Neighbor proteins around NZ_CP042828_3

CRISPR arrays

The CRISPR arrays of NZ_CP042828_3

>merge|NZ_CP042828|3|1631914-1632165|CRT
CGGCCACCGCCGACGCCCCAGCCGACGCTCCGGCTGCTGAGCCCGCTGCAGACGCCCCGGCCGCCGAAGCAGCTGCTGAGGCAGCTGCGGAGGCTCCGGTTGAGGCTGCGACCGAGGCTGCCACGGAAGCTCCGGCTGAGGACGCGACTGAGGCTGCCACGGAGGCCCCGGCTGAGGCTGCCACGGAAGCTCCGGTTGAGGCTGCCACGGAGGCCCCGGCTGAGGCTGCGACCGAGGCTGCCACGGAGGCCC

>NZ_CP042828|3|1|1631914-1632165|CRT
CGGCCACCGCCGACGCCC	CAGCCGACGCTCCGGCTGCTG
AGCCCGCTGCAGACGCCC	CGGCCGCCGAAGCAGCTGCTG
AGGCAGCTGCGGAGGCTC	CGGTTGAGGCTGCGACCG
AGGCTGCCACGGAAGCTC	CGGCTGAGGACGCGACTG
AGGCTGCCACGGAGGCCC	CGGCTGAGGCTGCCACGGAAGCTCCGGTTG
AGGCTGCCACGGAGGCCC	CGGCTGAGGCTGCGACCG
AGGCTGCCACGGAGGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147916514.1|1633238_1633991_+|UMP-kinase	unknown	unknown	gnl|CDD|234735
NZ_CP042828.1|WP_147916509.1|1628121_1629072_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|234698
NZ_CP042828.1|WP_147919368.1|1634702_1635590_+|phosphatidate-cytidylyltransferase	unknown	unknown	gnl|CDD|366491
NZ_CP042828.1|WP_147916521.1|1641309_1642191_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379120
NZ_CP042828.1|WP_147916515.1|1633987_1634545_+|ribosome-recycling-factor	unknown	unknown	gnl|CDD|178850
NZ_CP042828.1|WP_147916507.1|1626607_1627321_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235500
NZ_CP042828.1|WP_147916506.1|1625337_1626501_+|DNA-protecting-protein-DprA	unknown	unknown	gnl|CDD|223829
NZ_CP042828.1|WP_168211688.1|1629212_1630004_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP042828.1|WP_147916513.1|1632252_1633092_+|elongation-factor-Ts	unknown	unknown	gnl|CDD|236491
NZ_CP042828.1|WP_147916504.1|1621970_1622762_+|ribonuclease-HII	unknown	unknown	gnl|CDD|260003
NZ_CP042828.1|WP_147916520.1|1640117_1641281_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl|CDD|234737
NZ_CP042828.1|WP_147916519.1|1638617_1639970_+|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|100084
NZ_CP042828.1|WP_147916505.1|1623430_1623787_+|YraN-family-protein	unknown	unknown	gnl|CDD|237119
NZ_CP042828.1|WP_147916517.1|1636854_1637400_+|DivIVA-domain-containing-protein	unknown	unknown	gnl|CDD|188337
NZ_CP042828.1|WP_147916511.1|1629994_1630720_-|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NZ_CP042828.1|WP_147916508.1|1627377_1627926_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP042828.1|WP_022916852.1|1622808_1623114_+|DUF2469-domain-containing-protein	unknown	unknown	gnl|CDD|313765
NZ_CP042828.1|WP_147916518.1|1637396_1638605_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl|CDD|235472
NZ_CP042828.1|WP_147919367.1|1623803_1625345_+|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl|CDD|223679
NZ_CP042828.1|WP_147916516.1|1635586_1636759_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl|CDD|184689

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147916514.1|1633238_1633991_+|UMP-kinase	gnl|CDD|234735	PRK00358, pyrH, uridylate kinase; Provisional.	1.06564e-129
NZ_CP042828.1|WP_147916509.1|1628121_1629072_+|tyrosine-type-recombinase/integrase	gnl|CDD|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	1.54276e-115
NZ_CP042828.1|WP_147919368.1|1634702_1635590_+|phosphatidate-cytidylyltransferase	gnl|CDD|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	6.50609e-56
NZ_CP042828.1|WP_147916521.1|1641309_1642191_+|GNAT-family-N-acetyltransferase	gnl|CDD|379120	pfam13312, DUF4081, Domain of unknown function (DUF4081). This domain is often found N-terminal to the GNAT acetyltransferase domain, pfam00583 and FR47, pfam08445.	5.41527e-35
NZ_CP042828.1|WP_147916515.1|1633987_1634545_+|ribosome-recycling-factor	gnl|CDD|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	1.335e-94
NZ_CP042828.1|WP_147916507.1|1626607_1627321_-|SDR-family-oxidoreductase	gnl|CDD|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	7.9867e-51
NZ_CP042828.1|WP_147916506.1|1625337_1626501_+|DNA-protecting-protein-DprA	gnl|CDD|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	4.54938e-91
NZ_CP042828.1|WP_168211688.1|1629212_1630004_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.56151e-15
NZ_CP042828.1|WP_147916513.1|1632252_1633092_+|elongation-factor-Ts	gnl|CDD|236491	PRK09377, tsf, elongation factor Ts; Provisional.	4.29312e-124
NZ_CP042828.1|WP_147916504.1|1621970_1622762_+|ribonuclease-HII	gnl|CDD|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	7.17662e-72
NZ_CP042828.1|WP_147916520.1|1640117_1641281_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl|CDD|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NZ_CP042828.1|WP_147916519.1|1638617_1639970_+|PDZ-domain-containing-protein	gnl|CDD|100084	cd06163, S2P-M50_PDZ_RseP-like, RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog RseP is involved in the sigmaE pathway of extracytoplasmic stress responses. Also included in this group are such homologs as Bacillus subtilis YluC, Mycobacterium tuberculosis Rv2869c S2P, and Bordetella bronchiseptica HurP. Rv2869c S2P appears to have a role in the regulation of prokaryotic lipid biosynthesis and membrane composition and YluC of Bacillus has a role in transducing membrane stress. This group includes bacterial and eukaryotic S2P/M50s homologs with either one or two PDZ domains present. PDZ domains are believed to have a regulatory role. The RseP PDZ domain is required for the inhibitory reaction that prevents cleavage of its substrate, RseA.	4.12448e-39
NZ_CP042828.1|WP_147916505.1|1623430_1623787_+|YraN-family-protein	gnl|CDD|237119	PRK12497, PRK12497, YraN family protein.	2.50424e-43
NZ_CP042828.1|WP_147916517.1|1636854_1637400_+|DivIVA-domain-containing-protein	gnl|CDD|188337	TIGR03543, divI1A_rptt_fam, DivIVA domain repeat protein. Members of this protein family contain two full and two partial repeats of a domain found at the N-terminus of Bacillus subtilis cell-division initiation protein DivIVA. The portion repeated four times in these proteins includes the motif GYxxxxVD.	1.68839e-58
NZ_CP042828.1|WP_147916511.1|1629994_1630720_-|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	5.8236e-17
NZ_CP042828.1|WP_147916508.1|1627377_1627926_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.18446e-10
NZ_CP042828.1|WP_022916852.1|1622808_1623114_+|DUF2469-domain-containing-protein	gnl|CDD|313765	pfam10611, DUF2469, Protein of unknown function (DUF2469). Member proteins often found in Actinomycetes clustered with signal peptidase and/or RNAse-HII.	7.49789e-63
NZ_CP042828.1|WP_147916518.1|1637396_1638605_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl|CDD|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP042828.1|WP_147919367.1|1623803_1625345_+|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl|CDD|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	2.14947e-170
NZ_CP042828.1|WP_147916516.1|1635586_1636759_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl|CDD|184689	PRK14459, PRK14459, ribosomal RNA large subunit methyltransferase N; Provisional.	0

Protein sequences

>NZ_CP042828.1|WP_147916511.1|1629994_1630720_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MRSPPQRHGPPPRTSCRVLSALLLALAVLAGIAPARAAPANTPTPGPLLLAPAGARGTGSLDTGPLLTGPLGTRPLSTGPPATRPLSTEPLPTDISTSQSGYDWPVAGDGGAPAVLRRFDPPPLPWLSGHRGVDLAAEAGATVRAAGPGTVAFAGMVAGRPVVSIQHTDGLRTTYEPVTPTVQAGDAVDRGSMIGQLSDAGSHCESTCLHWGVRTGRDDYLDPLLLLGAEVVIRLYPPTQG
>NZ_CP042828.1|WP_168211688.1|1629212_1630004_+|class-I-SAM-dependent-methyltransferase
MATMPAYSPDAAARYDRTAEPLMVPLAAVLVDAAQVHLEAAVLDVVCGPGFAARIAAERAGPMGTVVGVDPDPAMLQVASGHGAGYAIEWLQAEPDSLPLASGSQDVVVSLHGMTALAEPRPALGEALRVVREDGSFAATVWSPIEANPYLTAHARALTEQGSTGAVEVLRAATGYGADDLVGDLRAAGWHEPVSREVTLRIRLAGTIAAAAERLRGMPWGARLDAEEALAAARSMLTSLVEFAEADGSLVVPFRAQLVHAYP
>NZ_CP042828.1|WP_147916509.1|1628121_1629072_+|tyrosine-type-recombinase/integrase
MITTEQQRDAGLLDAFASHLAIQRGLSEHTVRAYCGDVLTMLALLPHGADGTDPADLSRLSLPVLRQWLAQESGRGLSRATLARRVAAVRCFTAWAQRTDRIAADPGQRLLSPRPGSTVPQVLSAAEAAAVMDAARDRIAAADETVTAARATRDWAVLELLYATGVRVSELVGADVTDLNLGDRLLRVLGKGDKERMVPFGRPASTAVERWLAVREHLLVTGPTDSGALFLGNRGGRLGARQVRDLVHRTTALAGVRDLAPHGLRHSTATHLLDGGSDLRSVQEVLGHASLSTTQRYTHVSTERLRSAFAQAHPRA
>NZ_CP042828.1|WP_147916508.1|1627377_1627926_+|MarR-family-transcriptional-regulator
MTAHVSRGGDQGRSGDLQRARSVATAWQRELPDVPTRSIALVWLVKAVAVALRNGRAGLLDQLGIDAATLDLLSTLRRRGEPYRLTTRQLAERCLVSAGAISQRITRAERDGLVLRNPGEGRSVEVALTERGHQLVERTAGKVLAADDDVTAEIGDEDLGRLEQLLSAWLASMKESGGAAGS
>NZ_CP042828.1|WP_147916507.1|1626607_1627321_-|SDR-family-oxidoreductase
MNKTALVTGGTRGIGRAVAEQLIADGYEVVVTSRSTKVGPQATEWGARGLRLDVADVDSVAALGDHLTAVDVLVNNAGAFAAPTPAPGAPLSDVAAAWRHNLDVNLVGAALLVTALEDRLRAGGSVVSIGSIGAEYAGNPYSVAKAALQAWNVGLAERLGPRDITANVVSPGYTEGTDLFGGPLPEARHTRLVERTTLGRPGRPADIAGAVAFLASAQARQITGQTIHVNGGAYTTR
>NZ_CP042828.1|WP_147916506.1|1625337_1626501_+|DNA-protecting-protein-DprA
MSDRLPFDTSDDRMARAAWSRIAEPRDAQAGALVQALGAGPALQWLAAAAQAWSDPPVLAPGARWHTAAQRWIPRLTGLDLRRELDVLARRGGRVLIPDDPEWPAGLADLGTDAPPCLWLLGDPSALSRPAVAVVGSRACSPYGAEITNTMTTELAADGLVIVSGGAFGVDAAAHRATLAGDGAPVAVMAGGLDRFYPVGNAALLAEVAQYGAVLSEVPPGSSPMRQRFLSRNRLIAALAEVTVVVEASWRSGALNTAGHAAELGRTVAAVPGPVTSSTSAGCHRLIREGAVCVTDAAEVLELVGPWDAAAGAGEPPVAAGLLDGLGPGQAQVLDAMPARAGVELAGLVRSSGVGEPEVRSALGFLELAGRVERDGVRWRRARKQRT
>NZ_CP042828.1|WP_147919367.1|1623803_1625345_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MRAARTLSVAIVGLQGQVMEVETALHQGLPAVQLIGLPDTAAAEARERVRAAVIATGLTWPSVRLVVNLRPADLRKSGSGFDLAVAVAVLRAAGLAPARRSEHRVHLGELGLDGTVHPIRGVLPAVAAAVAAGHPEVVVPADNVPEAELVPGAQVTGVQHLSELAFAYGAEGLRRLPPAPLARAEVAALPEPAAKDLADVIGQEQARHALEVAAAGGHHLFLNGPPGAGKSMLAACLPGLLPDLDDAAAVEVTTVHSVAGSYQPTTGLIRRPPYEAPHHTASKAAIIGGGSRTLRPGAVVRAHRGVLFLDEAAEFSRSVLDTLRQPVEEGHVVLQRAKETATYPCRIQLVLAANPCPCGWATGKGLRCRCSPNALRLYQNKLSGPLLDRVDIRVDVASVTRTQLLGAATGESSAAVAARVAAARQAQTRRWADTPWRTNAEVDGPWLRAYTRRIDDALLDPLRRPGDTSELTMRGVDRVVRVAWTLADLQGLDHPGPTEIGAALTLRNRDLHV
>NZ_CP042828.1|WP_147916505.1|1623430_1623787_+|YraN-family-protein
MAAKDVLGRTGEELAGRWLERAGWEILDRNWRCRTGEIDLVALDGDDLVVVEVKTRRSLRLGHPAEAVTARKLARLRVLAGQWLAEHDVRAAGLRVDVIAVWLPDDGPARIDHRQGVS
>NZ_CP042828.1|WP_022916852.1|1622808_1623114_+|DUF2469-domain-containing-protein
MSSEDLENYETDMELALYREYRDVVSLFSYVVETERRFYLANHVDLQVRSAGGEVFFELTLADAWVWDVYRSARFVKSVRVVTFKDVNVEELAKPELDLPS
>NZ_CP042828.1|WP_147916504.1|1621970_1622762_+|ribonuclease-HII
MVEQPHRHVRRRPRPVRSSPPTRMLERELLGAGHHLVAGMDEVGRGALAGPVSVGVAVVDASTGRMPAGLRDSKLLRPEMREKLQAPIRRWCLAGAVGHALPAEIDRFGIIAALRLAGTRALTTLRETGVVPDVVILDGSHDWLTPPGSQPGLSTTAPGLFTDHAPPVVRTQVKADLRCAVVAAASVLAKCERDAMMVARHPEYPAFGWQNNKGYSAPEHLAALREHGPCEEHRRSWALPTGEEPMAQALFIEGELAGGTRAP
>NZ_CP042828.1|WP_147916513.1|1632252_1633092_+|elongation-factor-Ts
MANYTAADIKALRERTGAGMLDVKKALDEADGDQTKALEIIRVKGLKGVSKREARAASDGLVATSINDEGAGQVGVLVEVNSETDFVAKNEVFTSLAEKVVAAAAASGATDAEQLLAAEADGGTVASMVEETAATLGEKIVVRRVARVSGEKVSEYLHRTNKDLPPQVGVLVASDAAGAAVARDVAMHIAAFSPTYLSREDVPADKVADERRIAEETARNENKPEQALPKIIEGRLNGFFKEVALLDQPFAKDPKQTVGQIVAATGGTLTGFARFRVGA
>NZ_CP042828.1|WP_147916514.1|1633238_1633991_+|UMP-kinase
MTTASPAARRVLLKLSGEVFGGGSVGLDPDMVSAIAREIATAVHDGIQVAIVVGGGNFFRGAELSQRGLDRARADYMGMLGTVMNCLALQDFLEKASVSTRVQTAITMGQVAEPYIPLRAIRHLEKGRAVVFGAGAGMPYFSTDTVAIQRALETHCEEVLVGKNGVDGVYTADPRTDPTAVRIDHLTFDEAIQKDLRVVDSTALALCRDNRLTMRVFGMGTPGNVAGALKGEKIGTIVTSEPDPQTKEQA
>NZ_CP042828.1|WP_147916515.1|1633987_1634545_+|ribosome-recycling-factor
MIDETLLEAEEKMDKAVEVAREDFAGIRSGRANAGMFEKIEVDYYGAPTPLQQLASVTIQEARTVLIGPYDKGAMTTIEKALRESDLGVNPGNDGNVIRVVLPTLTEERRRDYVKLAKSKGEDARVALRNVRRRAKEELDRIAKDGEAGEDEVARAQSELDSLTKKHTDIVDALLAGKEKELLEV
>NZ_CP042828.1|WP_147919368.1|1634702_1635590_+|phosphatidate-cytidylyltransferase
MGQAELPASPVEEPEPRDLLAEPEPASRAGRNLPVAIGVGLGLGAVLLASLLIRKEVFLGLAILACVGALWELDRSLRTRDIRLPMLPLAVGTVGMLVSAYTAGIEALLVAFVLTAGGVFVWRVVDGGGVVALREATTGIFAAAYIPFLAGFLTIMLSADDGELRVLMLIALVVANDTGGYTAGVLFGRHPMAPTVSPKKSWEGAIGSLVLAVAVGVGFALWGLDLDWWAGAVLGVVAVLGAIIGDLAESLLKRDLGVKDMGTLLPGHGGILDRVDSILLASPVVFAVMLVLAPT
>NZ_CP042828.1|WP_147916516.1|1635586_1636759_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MSENGAIMSSQPQVLPGHAPDAESRPQLSFAVPRRGKPPRHLADLTLAERIEVLGELGEPGYRAKQLSTHYFARLTRDPEQMTDIPAASRQQMSDLLLPDLLHEDRRLTADDGATVKTLWSLFDDVKVESVLMAYPGRATLCVSSQAGCGMACPFCATGQMGLTRNLSTAEVIEQVRHAAVMCAGGELAGGERRLTNVVFMGMGEPLANLKTVLGAVRRMVAPPPEGLGMSARHITVSTVGLVPAIRRLTTEGIPVTLALSLHAPDDELRSELVPINSRWSVAEALDAARAYFEATGRRVSIEYALIKDMNDHGWRADLLAAELNKRGNGWVHVNPIPLNPTPGSIWTASEKHVEDEFVARLRSAGIPTTVRDTRGSDIDGACGQLAAQE
>NZ_CP042828.1|WP_147916517.1|1636854_1637400_+|DivIVA-domain-containing-protein
MADLFPTVKGWGSGYDRDEVEDFFTRARSAYEDGTAELDGGDVRTVAFELDRGGYDPAAVDAALDRLEAAFVQRRRADHIAAHGQEDWMEQVAERATTLYPRLVRPAGERFAPPERGRGYQATAVDAVLDKLVDYFDTGTALTAGQLRNVTFPSASRSRAYAEGPVDAFLDRAVDVLLAVE
>NZ_CP042828.1|WP_147916518.1|1637396_1638605_+|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MTRRVTVLGSTGSIGTQAIEVITAHPEAFRVQALAAGGSNPVLLAQQVLQVGAARVAIADDGAVPAFRAALTEAAARAGSSGRQVEVLTGAAGVAEVAGDGADVVLNGITGSIGLAPTLAALAAGSVLALANKESLIVGGSLVTRAAAQGQIVPVDSEHSAIAQCLRAGSAAEVRRLVLTASGGPFRGRSRAELAEVTPAEALRHPNFAMGPVVTTNSATMVNKGLEVIEAHLLFEVPFNDIEVVVHPQQQIHSMVEFRDGSTIAQAGPPRMLVPIALGLSWPERLTGVDTPCDWSRASSWEFAPLDHEAFPAVRLAERAGRAGGTFPAVYNAANEVCVAAFHAGELSFPAITDVLAQVVDSHAGTVGDPVRRTGAELTLAGVLAADGWAREHAQRAVRNAT
>NZ_CP042828.1|WP_147916519.1|1638617_1639970_+|PDZ-domain-containing-protein
MDFWLGVLIVAVGLIVSIALHELGHLVPAKLFKVKVSQYFVGFGKTLWSTRRGGTEYGIKMLPLGGYVRMIGMFPPAEDTRSEDARTEERVRRTGLRGMAASVIEDTRAASTAELTDELRPGDGYKAFYELTTPRKLAVMFGGPVVNLIISAVLFAIILTGFGLATPSNQLGSVAECVVPATEERDCTASDPASPAAAAGLQPGDRIVSWNGTPVDSWADVTAGIEATGTDPAEVEVQRGEETLTLTVTPELTERPQVSDGEYVLDDDGAPVLAEQAYVGIGATYELYRQPISEVPAYVGNVLVSTFEVVLTLPQRLVSIAQSTFGGGERDPGVVGLIGVGRFAGEITSIDAAQYGMKERTADLLSLVASLNMALFVFNMIPLLPLDGGHVAGALFEGARRRLAQLFGRPDPGHADTAKLMPLTYVVLVVLVGMSLMLAVADIFNPVTLL
>NZ_CP042828.1|WP_147916520.1|1640117_1641281_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MNVPVNMGMPTVKEAPPVLAPRRRTRAIRVGSVPVGGDAPISVQSMTTTPTSDINATLQQIAELTAAGCDIVRVAVPTGDDAAALPAIAAKSQIPVIADIHFQPRYVFAAIDAGCAAVRVNPGNIRKFDDQVKEIAAAAAAADVSLRIGVNAGSLDKRLLEKYQKATPEALVESAVWEASLFEEHGFHDFKISVKHNDPVVMVRAYELLAEVGDWPLHLGVTEAGPAFQGTIKSATAFGALLSQGIGDTIRVSLSAPPVEEVKVGLQILQSLNLRERKLEIVSCPSCGRAQVDVYTLADEVTAGLEHLTVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEAEIVTTLLAEANRIAEQMGSEQESGPVAVTVS
>NZ_CP042828.1|WP_147916521.1|1641309_1642191_+|GNAT-family-N-acetyltransferase
MPSWPRRSRTARPAPALDVRDARGLPTGDIRDFCLQAPVDAALLGEHVEALGRFSFYGDQLWCLMAGGSLQGLCWTGGNVVPYRMPPGGAELVAERLRARRRRYSSIVGPAQDVLPLWELLEADAPPPREVRADQPSLIITGEPLVAAEARVRLSDRADLDVLLPACVAMFTEEVGYSPMDAGNGYERRVRTLVESGRSLSWVAQTEYGREVIFKAELGTVALGVTQVQGVWVNPRYRGRGYAAAGMAAVVEYAQRHVAPVVSLYVNGYNTAALAVYRKVGFTQVGTFATVLF

Crispr_ID: NZ_CP042828_4

• CRISPR_ID: NZ_CP042828_4
• CRISPR_location: 1747358-1747421
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_4

Consensus_repeat	Method
CAGACCCTGACAGACGCCGACAGA	CRISPRCasFinder

spacers of NZ_CP042828_4

>4.1|1747382|16|NZ_CP042828|CRISPRCasFinder
CGCCGACAGACCCTGA

CRISPR arrays and Neighbor proteins around NZ_CP042828_4

CRISPR arrays

The CRISPR arrays of NZ_CP042828_4

>merge|NZ_CP042828|4|1747358-1747421|CRISPRCasFinder
CTGACCCCGACAGACCCTGACAGACGCCGACAGACCCTGACAGACGCCGACAGGCCCCGGCATA

>NZ_CP042828|4|3|1747358-1747421|CRISPRCasFinder
CTGACCCCGACAGACCCTGACAGA	CGCCGACAGACCCTGA
CAGACGCCGACAGGCCCCGGCATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147916612.1|1756382_1757009_+|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl|CDD|234873
NZ_CP042828.1|WP_168211698.1|1743531_1744290_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223673
NZ_CP042828.1|WP_168211700.1|1746861_1747329_+|hypothetical-protein	unknown	unknown	gnl|CDD|224159
NZ_CP042828.1|WP_168211699.1|1745867_1746830_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270370
NZ_CP042828.1|WP_147919382.1|1739939_1740404_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|225064
NZ_CP042828.1|WP_147916609.1|1754508_1754769_+|PspC-domain-containing-protein	unknown	unknown	gnl|CDD|377200
NZ_CP042828.1|WP_147916614.1|1757724_1758339_+|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl|CDD|237290
NZ_CP042828.1|WP_147916597.1|1740549_1741578_+|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176227
NZ_CP042828.1|WP_147916602.1|1745035_1745839_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213260
NZ_CP042828.1|WP_147916605.1|1747463_1748729_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|236095
NZ_CP042828.1|WP_147916608.1|1752782_1753022_-|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl|CDD|379097
NZ_CP042828.1|WP_147916610.1|1754845_1755211_-|DUF952-domain-containing-protein	unknown	unknown	gnl|CDD|377607
NZ_CP042828.1|WP_147916607.1|1752374_1752737_+|lactoylglutathione-lyase	unknown	unknown	gnl|CDD|319924
NZ_CP042828.1|WP_168211697.1|1742017_1743499_+|acyl--CoA-ligase	unknown	unknown	gnl|CDD|223395
NZ_CP042828.1|WP_147916598.1|1741574_1742015_+|hotdog-fold-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP042828.1|WP_147916601.1|1744286_1745039_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223673
NZ_CP042828.1|WP_147916611.1|1755261_1756386_+|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|235115
NZ_CP042828.1|WP_147916606.1|1748809_1752355_+|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|235554
NZ_CP042828.1|WP_147916596.1|1739007_1739943_+|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|161659
NZ_CP042828.1|WP_147916613.1|1757005_1757728_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147916612.1|1756382_1757009_+|imidazoleglycerol-phosphate-dehydratase-HisB	gnl|CDD|234873	PRK00951, hisB, imidazoleglycerol-phosphate dehydratase HisB.	4.75484e-119
NZ_CP042828.1|WP_168211698.1|1743531_1744290_+|ABC-transporter-permease-subunit	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	9.02078e-39
NZ_CP042828.1|WP_168211700.1|1746861_1747329_+|hypothetical-protein	gnl|CDD|224159	COG1238, COG1238, Predicted membrane protein [Function unknown].	2.55674e-06
NZ_CP042828.1|WP_168211699.1|1745867_1746830_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270370	cd13652, PBP2_ThiY_THI5_like_1, Putative substrate binding domain of an ABC-type transporter similar to ThiY/THI5; the type 2 periplasmic binding protein fold. This subfamily is phylogenetically similar to ThiY, which is the periplasmic N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP) binding component of the ABC transport system (ThiXYZ). FAMP is imported into cell by the transporter, where it is then incorporated into the thiamin biosynthetic pathway. The closest structural homologs of ThiY are THI5, which is responsible for the synthesis of 4-amino-5-(hydroxymethyl)-2-methylpyrimidine phosphate (HMP-P) in the thiamin biosynthetic pathway of eukaryotes, and periplasmic binding proteins involved in alkanesulfonate/nitrate and bicarbonate transport. After binding the ligand, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ThiY/THI5 proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.93658e-39
NZ_CP042828.1|WP_147919382.1|1739939_1740404_+|GNAT-family-N-acetyltransferase	gnl|CDD|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	3.42636e-20
NZ_CP042828.1|WP_147916609.1|1754508_1754769_+|PspC-domain-containing-protein	gnl|CDD|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	1.19945e-10
NZ_CP042828.1|WP_147916614.1|1757724_1758339_+|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl|CDD|237290	PRK13146, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	9.75399e-101
NZ_CP042828.1|WP_147916597.1|1740549_1741578_+|zinc-binding-dehydrogenase	gnl|CDD|176227	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family. This group contains proteins related to the zinc-dependent alcohol dehydrogenases. However, while the group has structural zinc site characteristic of these enzymes, it lacks the consensus site for a catalytic zinc. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.6623e-104
NZ_CP042828.1|WP_147916602.1|1745035_1745839_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.86115e-110
NZ_CP042828.1|WP_147916605.1|1747463_1748729_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|236095	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC.	1.53567e-174
NZ_CP042828.1|WP_147916608.1|1752782_1753022_-|RNA-binding-S4-domain-containing-protein	gnl|CDD|379097	pfam13275, S4_2, S4 domain. The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4.	2.79916e-24
NZ_CP042828.1|WP_147916610.1|1754845_1755211_-|DUF952-domain-containing-protein	gnl|CDD|377607	pfam06108, DUF952, Protein of unknown function (DUF952). This family consists of several hypothetical bacterial and plant proteins of unknown function.	1.64041e-27
NZ_CP042828.1|WP_147916607.1|1752374_1752737_+|lactoylglutathione-lyase	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.97335e-27
NZ_CP042828.1|WP_168211697.1|1742017_1743499_+|acyl--CoA-ligase	gnl|CDD|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.46555e-108
NZ_CP042828.1|WP_147916598.1|1741574_1742015_+|hotdog-fold-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	2.85661e-23
NZ_CP042828.1|WP_147916601.1|1744286_1745039_+|ABC-transporter-permease-subunit	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	6.52488e-48
NZ_CP042828.1|WP_147916611.1|1755261_1756386_+|histidinol-phosphate-transaminase	gnl|CDD|235115	PRK03317, PRK03317, histidinol-phosphate aminotransferase; Provisional.	0
NZ_CP042828.1|WP_147916606.1|1748809_1752355_+|DNA-polymerase-III-subunit-alpha	gnl|CDD|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NZ_CP042828.1|WP_147916596.1|1739007_1739943_+|RluA-family-pseudouridine-synthase	gnl|CDD|161659	TIGR00005, Ribosomal_large_subunit_pseudouridine_synthase_D, pseudouridine synthase, RluA family. In E. coli, RluD (SfhB) modifies uridine to pseudouridine at 23S RNA U1911, 1915, and 1917, RluC modifies 955, 2504 and 2580, and RluA modifies U746 and tRNA U32. An additional homolog from E. coli outside this family, TruC (SP|Q46918), modifies uracil-65 in transfer RNAs to pseudouridine. [Protein synthesis, tRNA and rRNA base modification].	3.80655e-100

Protein sequences

>NZ_CP042828.1|WP_168211700.1|1746861_1747329_+|hypothetical-protein
MWELAAAFGYCALSAVVMVLPAELYLLGAAALTETGGIWLALAGAVGQVAGKMLSYLVGRGVLSTKRLRSRAKGRWVDRMTRVEQWCTAHEWGPAAVTFVSAFAGLPPYALVAVLAGSLRMPWWLFAGVSLVGRFLRFWAVVSIPHLLPGSLFGI
>NZ_CP042828.1|WP_168211699.1|1745867_1746830_+|ABC-transporter-substrate-binding-protein
MKARTLIAPLAVAALALTACGGEDNTNEEGQYELTVMQITTMDSAPLYLGVEEGIFAEHGLDVTIEIAEAGSAIVPSVVNQESPIGYANAVSDLQAIDQGLDLRFVANCCGVGADPEADTSALFVLPDGPITEVGDLAGANIAVNSVNNLGDLTIDTALANEGVDTSGVTYTPMNYSDMSAALERGDVDAIWSVEPFRSISEETGFVNVIDNFVASFPDTTIGYYITSGPFAEENPEIVASFQEAMSEANEFATENPDRVRETVVRELELDPELVEGANFGVFAPGLDTESLRTIGAAALEAGMISAEPDYDAVVVQPQD
>NZ_CP042828.1|WP_147916602.1|1745035_1745839_+|ATP-binding-cassette-domain-containing-protein
MTTATPLIEVDGLHKVYGHGDRAFEALADITASIGDGEFFTVVGPSGAGKTTLLRCLAGLLEPSTGSVSFRGKPIDGVPREFALVLQDYSRSLLPWFSVEKNVALPLRAHKVPKAEIADRVQRALREVGLSDAARKSPSELSGGMQQRVAIARAIAYRPEVLIMDEPFASVDAQTRADLEDLVLSLRTELGMTVVFVTHDVDEAVYLSDRVAVVSRSPSRITHVFDIDLPAERDQIATKQLPRFATLRAEVFAEIREHVRGATAGTS
>NZ_CP042828.1|WP_147916601.1|1744286_1745039_+|ABC-transporter-permease-subunit
MSAWTRGLLAVVGVVVALGAWWLLTADSTDPYVPPMVEVLRHAWEYWAGGEGRPHLLSSMANLGVGLAVAILAGLVLGLVIGQQRWLDRALSPTGEFVRAIPATALVPLAMVLFGLGTTMKVVIIALGCFFPVLLNVIDGCRGISPTLHDTARSFGIRGPIRQFSVVLPAVYPRAAAGIRTAIPLALILVVTSEMTGSAVGVGFVLTTAQSSFDLTAVWSAIVLLGVLGVLLNLLFDLVERLIDRRYYQR
>NZ_CP042828.1|WP_168211698.1|1743531_1744290_+|ABC-transporter-permease-subunit
MPRWVLPTASTAALVLLVQLAVTVGVLPRSYVPAPSVIAGELAGLVTEMRTWGLVGNTIVAWAASLGVAIVLGTLGGVLFGSVRVVQAVLMPVIEFLRPIPSIAMIPLVVLTIGGGREGEVFLAGYAAFWQMLVAAVYATGSVDPVARDTARAYGFTLGQRLAWVTLPSMLPGLLTGVRIASATALIITITSEILIGAPGLGQGLNLARSGGDLPRMYAYVVAIGLVGLVLNGGLSALSRRLLHWHPSGRSR
>NZ_CP042828.1|WP_168211697.1|1742017_1743499_+|acyl--CoA-ligase
MSTNLGDAVATDRPDALALIDVGAPGETAQHWTYAELEHAIRARAAQLSERLAPGERVGLFGVNSAAWLVAELAIQRAGGVVVPISHKLPADGVAYVVQDASLQVVLADRDLAERRAGALAGADVIDLAAPVPDADFQTVATDPAADAMVLYTSGSTGRPKGVQLSHRSHLWVIEMLAAPVPPDSKRVLISAPLYHMNALSTAQRTFFAGGTLVVLPVFEPAAFWHAVTEHRVSEVSGVPPMFAIAAAHPLAGQVDSSSVKALYMGSAPAAPELFTRLRELFDGVAISFGYGTTESGPVVFGPHRDGLPVPDGSVGAAHPAVELRLVDADGTVRADRGVLEVRVPALLTGYLGLSEDQLPVTADGFHHTKDVFTVDADGFYTFDGREDDMFVSGGENVYPRAVERVLEQHPSVAEAVVVAVPDEVKGTKPVAFVTLVRADVDEDGLRRHVLAHLEPYAHPRRVWILTQLPLGTTNKPDRDALAARAATELGLR
>NZ_CP042828.1|WP_147916598.1|1741574_1742015_+|hotdog-fold-thioesterase
MTGATAATVTPAALTERINAAPLHRWLGLEVVEVSAAELRLRATWRPEWSNGTEAQVTHGGILATLLDLAADWCLFAAQAAVAPTLDFTTHFLRAAVPGDLDVVARPVKLGRAVSVAEAEVIDARGKTVATGRGSYAVFATSTPGE
>NZ_CP042828.1|WP_147916597.1|1740549_1741578_+|zinc-binding-dehydrogenase
MPSTMRALVLPAHGELDQVQLVENYPRPELRPGHVVIRVTASSWNYHDIFTVTGMPGITIPMPVVIGLDLVGEITELAEDVTGWSAGDRVLVHPLHPDRGLMGETLDGGMAEYALVDARQLVRIPAGVTDVQAAALPVAYGTAHRMVVGKGAVSAGDTVLILGASGGVGTASVLLAKQLGAHVIAAAGSQEKCRALEEIGADETLNYREVDFARWVKEHYGKPSRSSTETGVDVVINFTGGDTWHPTLRSVKLGGAILVCGATAGYDPVEDLRYIWSFELRVIGSNGFQTEDFEALLAMIDRGELDPVVSEVVSLEGALDGLRQVRDREVLGKIVVTPGARS
>NZ_CP042828.1|WP_147919382.1|1739939_1740404_+|GNAT-family-N-acetyltransferase
MMAAAVQVLRVSDAAGLRRVHALRFEVFVDEQGVSLGDELDEKDDLPGTVHLLAVADGQDLGTARLLVDGPGRVHVTRVAVRATARGLGLGRALMDETERIALAEHPAGGQVRVELSAQEGATGFYAALGYEIGSDRYLDAGIWHHDAVKTLHR
>NZ_CP042828.1|WP_147916596.1|1739007_1739943_+|RluA-family-pseudouridine-synthase
MADRRSLPVPDGLAGERVDAALSRMLGMSRTKVAELAGAGDVLMDGRVLGKSDRLVAGAWLEVSVPDLSADAATPPEPVPGMRIQHDDDDVVVVDKPVGVAAHPSPGWTGPTVVGALAAAGYRISTSGAAERQGVVHRLDVGTSGLMVVAKSERAYTVLKRAFKERTVTKVYHAVVQGHPDPTTGTIDAPIGRHPARDSRWAVVADGRPSVTHYETLEAMPGAVLLQIHLETGRTHQIRVHSAAIGHPCVGDLIYGADPRLAERLGLRRQWLHAMRLGFTHPGTGTWLEVTSSYPEDLAAALASLRAGSTH
>NZ_CP042828.1|WP_147916605.1|1747463_1748729_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MTPSPALPRGPWQRAARAAGLLQAAQVRPTIFAEMTALAQRTGAVNLGQGFPDTDGPASITAAAQEAIAAGANQYPPGPGHPDLLRAIADHQQRHYGLHVDPASEVLVTTGATEAIAAAVLALAGPGDEVLTLEPFYDSYAAIIALAGATHTTAPLHPTPAGFALDIEALRTAVTARTRLILLNSPHNPTGAVLEQTELAAIAAVAKERGAVVVTDEVYEHLTYDGATHVPIATLPGMGERTLTISSAGKSFALTGWKIGWVSGPAELVTAVRTVKQFLTYTTGAPFQPAIAVGLDLETTAGPDATWLTRQAASLAARRDLLLDGLHTAGLATATPRGAYFVMANAHSLLTGPLARTGISTGADLCRALPELAGVVAVPATAFTTPGSTADAGLTNWLRLTFVKSEPVITEAVARLTALSR
>NZ_CP042828.1|WP_147916606.1|1748809_1752355_+|DNA-polymerase-III-subunit-alpha
MAADFVHLHVHTEYSMLDGAARLDDLFAEAQRLGQTSLAITDHGYLFGAYDFWSKARKYGIKPIIGVEAYLTPGTSRFDKTRVRWGEEGQASDDVSARGAYTHMTLLSKNNTGMHNLFRMGSLASLEGQLGKWPRMDTELLSTYAEGLIATTGCPSGEVQTRLRLGQWDEAVRAAGEMQDIFGKENYYIELMSHGLEIERRVRSGLLELSRQIGAPLLATNDLHYTKHEDAHAHEALLCVQSSSTLEEPTYDQGGKRFALSGDGYYLKSAEEMRELFAELPEACDNTLRVAEQCEVSFTEEVGRYMPHFPVPEGEDEVSTFERAVETGLNQRYPAGIPEEVRQQAEYELEVITGKGYAGYYLVVADFINWAKDHGIRVGPGRGSGAGSMAAYAMSITELDPLEHGLIFERFLNPERMSMPDFDIDFDERRRGEVIKYVSDKYGEDKVSYIVTYGSIKAKQALKDASRVLGYPFAMGEKLTKAMPPAVMGKDITLPGMFDPDDARYAEADEFRQLVASDPEANRVLETARGLEGLKRQWGVHAAGVIIANEPLLDIIPIMRREQDGAVITQVDFPAGEDLGLVKMDFLGLRNLTILDDALENIVINGKDQVRVEDLTLDDPETYALLGRGDTLGLFQLDGGGMRTLLRLMRPDNFEDISAVGALYRPGPMGANSHTNYAMRKNGQQPITPIHPELAEPLESILGTTYGLIVYQEQVMEIAQKLAGYSLGQADLLRRAMGKKKKEVLDAEYSNFEAGMKANGYSANAVKTLWEILLPFSDYAFNKAHSAAYGLVSYWTAYLKAHYGCEYMAALLTSTRDDKDKSALYLNECRRMRITVLPPDVNASAATFTPVGDDIRFGLASVRNVGHNVVAAIAQAREEKGDFTSFTDFLDKVPAVVCNKRTIESLIKAGAFDSLGHTRRALLMVHEQAVDAVIGVKRKEAEGQFDLFAGLAGDDSDGGGFTVEIPDLPEWDKKQKLAFEREMLGLYVSDHPLSGIEHVLTQAADVSIATLIADESRPDGSTVTIAGLITSLQRKMSKKGNPWAAVTIEDMEGSVEVMFFGETYLAYSTALAHDQVVVLKGRARWRDESLTLQAMEMSLPDVSVGEEAPVAVRIAEARCSEPVLTRLRDVLSTHPGITEVHLHLTAPGRSTVMRLEDGLRVERTSSLYGDLKALLGPNCLV
>NZ_CP042828.1|WP_147916607.1|1752374_1752737_+|lactoylglutathione-lyase
MITGIGTAMLYVSDQEESLRFYRDLLGFTVVTDQEMGPGMRWVEVAPPQGSATIALHDAAAEGKAPGEGAYLTFACDDVAATVAELRRRGAVVSDPDEQPWGTFATVQGPDGHQVQFHRK
>NZ_CP042828.1|WP_147916608.1|1752782_1753022_-|RNA-binding-S4-domain-containing-protein
MATAETEDVPITGEMIRLGQLLKLTGICEDGASARILLSDDAVQVNGETETRRGRQLTPGDLLEIDLPHGERRLRVTSD
>NZ_CP042828.1|WP_147916609.1|1754508_1754769_+|PspC-domain-containing-protein
MRSFFDSLRRLNFRRGPARIVGGICGGLAASANASVTLVRVLVLVSFLLPFIGVGAYLVVWLLTPWQDGSIPLERFLDRSNRPPQA
>NZ_CP042828.1|WP_147916610.1|1754845_1755211_-|DUF952-domain-containing-protein
MDTLFHLADPDLWAAAVRTGRYTGSTKGRSLAEEGFVHCSFRSQLAGVAAALYSGTPALVLLEIDPELLGGAPLRVEAVPGSAHGFPHVYGPIPTAAVASATPVQVDEQGHIHDARIPGAG
>NZ_CP042828.1|WP_147916611.1|1755261_1756386_+|histidinol-phosphate-transaminase
MPERCAPSLPLRADLVGEQPYGAPQLDVPHLLNVNENPYPPPAEVVADIAAAVTEAAGTLNRYPDREFRDLRADLAAYLTAESAATGLTTDHLWAANGSNEVMLHLLLAFGGPGRTVMSFAPTYSMYPEYARDSLTTWKAGTRRADFSVDVAEAIEQIRTERPSVVLLASPNNPTGTALDSADVRALAEATADSGPDGGATVLVIDEAYAEFRREGRPSAVTLLGEFAHLAVARTMSKAFALAGARLGYLAAAPELVDWLRVVRLPYHLSAVTQAVARAALRHTGVLQAQVAELRVRRDETVTWLRERGLEVADSDANFILFGRYPDRHEVWQGLLDRGVLIRETGPQGYLRVSIGTREDMAAFRGALEEVTGR
>NZ_CP042828.1|WP_147916612.1|1756382_1757009_+|imidazoleglycerol-phosphate-dehydratase-HisB
MSQPTSEQPAARRARVERSTSESTVTVELNLDGTGTVDVATTVPFYDHMLTALGKHSLIDLTVRASGDTEIDVHHTVEDTAICIGQALREALGDKAGIARFGDALVPLDETLARAVVDISGRPYLVHEGEPAGQEYHLIGGHFTGALTRHVFESIAFHAGICLHVHLLSGRDPHHIAEAQFKALARALRAAVARDPRVSGVPSTKGAL
>NZ_CP042828.1|WP_147916613.1|1757005_1757728_+|hypothetical-protein
MTSGQGRGAGGAETPEEFDEAAFEAAFAAEFGQAVEPERTVRAENGDDGETSRGQADHPSPSPGEPPAAPEAAPSPEKRRVLAVVLTPIASAPVLAALCAMAEVDADIVPSKRGALAAKVITTSGELDPSELLTGAPAEATDLATVLSKTAKVGVVLLTARLGEGEDGITGTISGREYQGGEPGEEVSPGLILAHADDVVEQILLGTLDPAQAPGRLVPKEMSRWQAARLMAKQVRRRRP
>NZ_CP042828.1|WP_147916614.1|1757724_1758339_+|imidazole-glycerol-phosphate-synthase-subunit-HisH
MTGPEVVVLDYGSGNVRSAVRALERVGAQVQLTADPEAVAAADGLFVPGVGAFASVMAGLSGVGGPRMIERRLAGGRPVLGVCVGLQVMFSTGVEHGTPAAGLDQWPGVVDRLRADVVPHMGWSTVAPPAGSALFAGVEDQRFYFVHSYAAHTAPDYAQVTWSSHGESTFVAAVENGPLCATQFHPEKSGDAGAELLRNWLHTL

Crispr_ID: NZ_CP042828_5

• CRISPR_ID: NZ_CP042828_5
• CRISPR_location: 1858154-1858229
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_5

Consensus_repeat	Method
GACGGCTCCGCAGAGCCGACCGACG	CRISPRCasFinder

spacers of NZ_CP042828_5

>5.1|1858179|26|NZ_CP042828|CRISPRCasFinder
CCGAGCCGACCGAGCCGAGCGCCACC

CRISPR arrays and Neighbor proteins around NZ_CP042828_5

CRISPR arrays

The CRISPR arrays of NZ_CP042828_5

>merge|NZ_CP042828|5|1858154-1858229|CRISPRCasFinder
GACGGCTCCGCAGAGCCGACCGACGCCGAGCCGACCGAGCCGAGCGCCACCGATGGCTCCGCAGAGCCGACCGACG

>NZ_CP042828|5|4|1858154-1858229|CRISPRCasFinder
GACGGCTCCGCAGAGCCGACCGACG	CCGAGCCGACCGAGCCGAGCGCCACC
GATGGCTCCGCAGAGCCGACCGACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_168211580.1|1864629_1866561_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147916697.1|1851276_1852485_+|MFS-transporter	unknown	unknown	gnl|CDD|341027
NZ_CP042828.1|WP_147919399.1|1850778_1851198_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP042828.1|WP_147916694.1|1847048_1848551_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|234953
NZ_CP042828.1|WP_147916707.1|1862529_1863168_+|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|179314
NZ_CP042828.1|WP_147916699.1|1853662_1854649_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213230
NZ_CP042828.1|WP_147916701.1|1855450_1855951_-|FBP-domain-containing-protein	unknown	unknown	gnl|CDD|379860
NZ_CP042828.1|WP_147916713.1|1868606_1869830_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP042828.1|WP_147919398.1|1848688_1849432_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|223943
NZ_CP042828.1|WP_147916706.1|1861017_1862499_+|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl|CDD|235490
NZ_CP042828.1|WP_147916708.1|1863263_1864577_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
NZ_CP042828.1|WP_147916703.1|1858582_1859656_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147916712.1|1868020_1868527_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147916695.1|1849551_1849860_-|acylphosphatase	unknown	unknown	gnl|CDD|224174
NZ_CP042828.1|WP_147916704.1|1859655_1860009_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|367559
NZ_CP042828.1|WP_147916711.1|1866585_1867479_-|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|224651
NZ_CP042828.1|WP_168211709.1|1854741_1855443_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP042828.1|WP_147916696.1|1849923_1850634_+|TSUP-family-transporter	unknown	unknown	gnl|CDD|376667
NZ_CP042828.1|WP_147916698.1|1852890_1853670_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP042828.1|WP_147916705.1|1860199_1860922_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224332

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147916697.1|1851276_1852485_+|MFS-transporter	gnl|CDD|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.94896e-88
NZ_CP042828.1|WP_147919399.1|1850778_1851198_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.61691e-17
NZ_CP042828.1|WP_147916694.1|1847048_1848551_+|glutamate--tRNA-ligase	gnl|CDD|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP042828.1|WP_147916707.1|1862529_1863168_+|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	2.23184e-121
NZ_CP042828.1|WP_147916699.1|1853662_1854649_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213230	cd03263, ABC_subfamily_A, ATP-binding cassette domain of the lipid transporters, subfamily A. The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.	6.15297e-64
NZ_CP042828.1|WP_147916701.1|1855450_1855951_-|FBP-domain-containing-protein	gnl|CDD|379860	pfam16571, FBP_C, FBP C-terminal treble-clef zinc-finger. FBP_C is a family from the C terminal end of fibronectin-binding proteins. It forms an extended four-cysteine zinc-finger with a unique structural fold. Fibronectin-binding proteins bind to elongation factor G - EF-G, which is mediated by the zinc-finger binding to the C-terminus of EF-G. FBPs release ribosomes by competing with them for EF-G.	1.85429e-62
NZ_CP042828.1|WP_147916713.1|1868606_1869830_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.47313e-40
NZ_CP042828.1|WP_147919398.1|1848688_1849432_+|HAD-IA-family-hydrolase	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	1.18204e-32
NZ_CP042828.1|WP_147916706.1|1861017_1862499_+|3-isopropylmalate-dehydratase-large-subunit	gnl|CDD|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP042828.1|WP_147916708.1|1863263_1864577_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP042828.1|WP_147916695.1|1849551_1849860_-|acylphosphatase	gnl|CDD|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	3.23347e-28
NZ_CP042828.1|WP_147916704.1|1859655_1860009_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	1.72239e-21
NZ_CP042828.1|WP_147916711.1|1866585_1867479_-|SIS-domain-containing-protein	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	8.98088e-60
NZ_CP042828.1|WP_168211709.1|1854741_1855443_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.54501e-09
NZ_CP042828.1|WP_147916696.1|1849923_1850634_+|TSUP-family-transporter	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.64956e-11
NZ_CP042828.1|WP_147916698.1|1852890_1853670_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.81485e-07
NZ_CP042828.1|WP_147916705.1|1860199_1860922_-|helix-turn-helix-domain-containing-protein	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	1.70517e-41

Protein sequences

>NZ_CP042828.1|WP_147916701.1|1855450_1855951_-|FBP-domain-containing-protein
MTPLTEREIRRCFVNATRGQAQRATVPPLADLDWNRLDYFGWRDAKAPLAGYVIIEIDGGPIGILLRAPSKGGHQRQAVCAWCEDIVEVDGVSLFVAPRAGAAGRRGDSIGTLLCGDFRCSANVRRRPTRAEAGTDEGARERLVASRIAGLQRRAAQFVVEVSRTG
>NZ_CP042828.1|WP_168211709.1|1854741_1855443_+|helix-turn-helix-transcriptional-regulator
MTPPRSRREQQQLTRDALIRAGRVVFARDGYHQANLTLIATEAGYSKGAVYSNFDSKADLFLAMLEENIDVSLGDGAWDPFGSQAPDGCSADLPDEQEEVAGLIRGLSLATLEFIATAARDESLVAQLATRLDVLVEGYAAIVDPSQSEHQGLLPEEVGALLAALDQGAALLTLSGSRVIDQRILREGMRRLLTPTEEREPAGQKGEPVLHDEVTRRRIAAAISLGRGVEAAE
>NZ_CP042828.1|WP_147916699.1|1853662_1854649_-|ATP-binding-cassette-domain-containing-protein
MNEDVLQVTALTRRFGAVVANDDISLRVRAGAVVGLLGHNGAGKTTLVSQVVGLLRPDAGAIQVSGCDAVADPAAARRRVSIQPQGQAPIDGLSPRLAIEMSARLRGLSRTAARAAAQHLGEELDITEWLDRRALPDGRGLSGGIRRLTAFAMALAAPTPLLILDEPTNDVDAARRRLLWRAVRRRGDEGAGVLLVTHNVAEAEQIVDDLVILHRGKVVTSGSPAHLRGTQEDDLRLELQSPPAVAGAADEHAVPLAVRRRVRTGRRLLLTFPAGEAAVAVDWATTLRTRGIIEGYTLGPATLEDAYLSATTDRRLEPAETGQESAHA
>NZ_CP042828.1|WP_147916698.1|1852890_1853670_-|ABC-transporter-permease
MPEASAVVTGHVPRARHATTYITLVRWSLSQVGAMLPLIVVIQAALAAGIVIGFGFLIPGIDPATALFLSTGTPTVLLLVLGLVMVPQGVSRARTDGTFAYLRTLPLARPLLLAAELTIWLLVALPSVAVAVLVARLRYDLVLSLDWPVLIAAALLVTLTATAVGYAIAVSMPPTLAQLLTQVLVFFVLLFSPVTFPADQLPTWFQSVHDYLPARPGADLVRAGLVADTYAASGRDLVVLVLWCLAGIALSVRALVRRS
>NZ_CP042828.1|WP_147916697.1|1851276_1852485_+|MFS-transporter
MLRQPRSVLAVAFASIIAFMGIGLVDPILKPIADELGATPSEVSLLFTSYMAVMGLAMLLTGAVSSRLGAKKTLLLGLVIIILGAGMAGTQDGVAGIIAWRAVWGLGNALFVATALATIVSSARGSVGQAIVLYEAALGVGIAIGPVVGGLLGHLSWRGPFFGVSGLMLIAAVATIFLVPATPKPPRATSLAEPILALRHRGLLITGLTALLYNFGFFTLLAFTPFPLDLGALEIGGIFFGWGVLLAITSVWLAPRLQRRFGTLRPITGALLAFALILVVMAVFTDHKVVLAAGVILAGAALGINNTLITETVMKAAPVERGVASAAYSFVRFAGGAVAPWLAGYLGERVSVHLPFWVGAASVLAAALLITAGRRTLAHVEDPAQASGHTVAEAAELTAADS
>NZ_CP042828.1|WP_147919399.1|1850778_1851198_+|MarR-family-transcriptional-regulator
MDADTLGPDLLAVLARLNRWATSHARLDVSAAQARLLAQIERTGPVRTSDLARLDRSSQPTITAQLQRAEQEGWALRTADPQDGRASLVELTDAGRAVLREVRRARAAALTPRLDELSQAERDTLTRAIAVIDRLIASP
>NZ_CP042828.1|WP_147916696.1|1849923_1850634_+|TSUP-family-transporter
MSVTVFLLLGLTVLVAAFLQGSAGMGFAMLAAPIVSLVDPTLIPVMLLVLMIPLNAYVGWRERADLDWRGVGWISLGRFAGTFIGVWILVLVSVSQLSLLIGISTVLAAVVALLAPSFVPNRPGLAVVGLITGITETSTGVGGPPLALAYQHTSGPTLRSTVAVCFLVGEVISLAVLGLGGHIDGGTLVATAGFLPFLVLGSFLSRFTHHRLDGPLLRYLVLSFAVVSGVVVIIQA
>NZ_CP042828.1|WP_147916695.1|1849551_1849860_-|acylphosphatase
MAWFRHNKRQQARVTARRVVVTGDVQGVGFRAATVRQARAAGVTGWVRNRSDGRVDAWAEGPAEAVAELVDWLANGPRHAVVTEREVTDEQPQGYTTFEIDR
>NZ_CP042828.1|WP_147919398.1|1848688_1849432_+|HAD-IA-family-hydrolase
MLFDLDDTLLDTAAAFAAAVAAVAAQFLPHLEPARYPEVLATWRADTGGHYQAHVDGLVDYRTQRFARAQQIQDEFGGTALDNAGYERWAQVWDATFSTSWVAFDDAAAILAELRSAGLAVGCVTNASTAQQSAKLAAVGLIDAVPLLVTLDTFGVGKPDPRVFHEGARLLGVDPGQVLYVGDEPLIDARGATAAGLRGVWLDRPGRRRGTPGEDPDALAADGIGVIQGLADVLDLVPGAANAPSRS
>NZ_CP042828.1|WP_147916694.1|1847048_1848551_+|glutamate--tRNA-ligase
MMTDTSSPSGVRVRFCPSPTGTPHVGLIRTALFNWAQARHTGGTFVFRIEDTDAARDSEESYTQLLDALSWLGLDWDEGVEVGGPHAPYRQSQRMDLYADVAAQLLAAGHAYESFSTPEEVGDRHRAAGRDPKLGYDGFDRDLTEEQKAAFRAEGRLPVLRLRMPAEDLTFTDLVRGEVTFKAGAVPDFVIVRGNGQPLYTLVNPVDDALMQITHVLRGEDLLSSTPRQIALYHALLDIGVASLVPVFGHLPTVTGEGNKKLSKRSPESNLFLHRERGFIPEGLLNYLALLGWSISPDNDIFTREEMVAAFDVADVNPNPARFDVKKAEAINAAHLRLLAPEDFRSRLVPYLHAAGVLPVAAYDELDPAQQELLTAAAPLVQERMSLLGEAPGMLGFLFTGDGEVTIAEDARGALREEAAEVLDRSIAVLADLADFSADAQQGALRAVLVDELGIKPRFAFAPLRVAITGRRVSPPLFESMEILGRDSALTRLRALRATL
>NZ_CP042828.1|WP_147916703.1|1858582_1859656_-|hypothetical-protein
MMPTRTPQTLDDVAGYFRHARGEQADEDWARAAAARLVLDDVREPLIREALFEVVPVLEDAQEPAETLFGDAIGWAKERQADWRSDGVPASAPSGPRSVRAFVHGTFFGAAAATPAFALLRMFADGWTLDFTLILVIFPLLLSVGVLGFLALWNWLVRRRARGTAIAVTALALIGFSAAVAGGFALSHEEVLWRGSGFWLFAVAAGYGLLAAGTRWIWPELPPPDPDHQVEGDLAWKRLLAASLRERGDITEGRLKVIIADAERHSAQSQRSLAEEFGSPASYAARFAPDVAVRARRTAWGWTAVAIAPIAVFVLYGLEDGWHWQARFLALGLWFAGAAVAAATSWRRATGQAAERF
>NZ_CP042828.1|WP_147916704.1|1859655_1860009_-|helix-turn-helix-transcriptional-regulator
MSDEPIDPRWPTPWVRAALGTATLAVLSDGPLHGYGIAVTLAERGFGRPKGGSLYPLLATLEAEGAVTAIWAQGASGPGRKTYALTDAGRARLAQERASWSHLVEELGHRGTAERSS
>NZ_CP042828.1|WP_147916705.1|1860199_1860922_-|helix-turn-helix-domain-containing-protein
MDNSSGVGVLDKAATVLGALEAGPATLAQLVAATHLARPTAHRLAVALEHHRFVARDMQGRFILGPRLAELAASAGEDRLLAAAGSVLMALRDHTGESAQLFRRQGDQRICVAAAEKTMGLRDSIPVGATLSMLAGSAAQVLLAWEEPDRLHRGLHGAKFTATILSGVRRRGWAQSVSERELGVASVSAPVRGPSGRVIAAVSVSGPIERMTRQPGRLHANAVMAAANRLTEVLRASEEN
>NZ_CP042828.1|WP_147916706.1|1861017_1862499_+|3-isopropylmalate-dehydratase-large-subunit
MAGTLAEKVWRDHVVREGQDGAPDLLYIDLHLVHEVTSPQAFEGLRLAGRPVRRPDLTIATEDHNTPTLDIDLPIADLTSRTQIDTLRRNAEEFGVRLHSLGDADQGIVHQVGPQLGLTMPGLTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPLAPFKTMAITVDGELPPGATSKDIILAIIAKIGTGGGQGYVLEYRGEAIRNLSMEARMTICNMSIEAGARAGMIAPDQTTFDYLAGRPHAPEGADWDAALEYWKTLRSDDDAVFDTEVVLEAADLEPFVTWGTNPGQGLPLSGSVPVPEEIGDDNERVAAERAVEYMGLVPGTPLRDIAVDTVFIGSCTNGRIEDLRSVAKVLEGRKKAESVRVLVVPASARVRLQAEAEGLDEIFLNFGAEWRNAGCSMCLGMNPDQLQPGERAASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSLSDLNLGAETDLTSFDGSPLAPLDPRVPMQV
>NZ_CP042828.1|WP_147916707.1|1862529_1863168_+|3-isopropylmalate-dehydratase-small-subunit
MEKFTTHTGLGVPLRRGNVDTDQIIPAVYLKRVTRTGFEDALFAAWRGDPEFVLNQEAYTSGSVLVAGPDFGTGSSREHAVWALKDYGFKAVLASRFADIFRGNSGKQGLVAAQLAQEDIELIWKVLEAEPGTEVTVDLEHKTVTCADVVAQFQIDDYTRWRLMEGLDDIGLTLGHEEDIVTYEATRADWRPRTLPAKHLPTIEVTPARPVS
>NZ_CP042828.1|WP_147916708.1|1863263_1864577_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MSQLRVDGGTPLSGEITVRGAKNFVSKAMVAALLGEGPSELRNVPEIRDVKVVAGLLKLHGVQVQRDIAGGVVHLDPSNVESAHKADIDTHAGASRIPILLCGPLLHRLGEAFIPDLGGCRIGDRPIDYHLEILRQFGAQVDKLDTGILITAPRGLRGTKVDLPYPSVGATEQLLLTAVRAAGVTELSGAAIEPEIMDLIAVLQRMGAIISVDTDRVIRVEGVDRLGGYVHTALADRIEAASWAAAALATRGDVYVRGAQQPGMMTFLNTFRKVGGSFDIDDAGIRFRHPGTELRSIVLETDVHPGFMTDWQQPLVVALSQASGLSIVHETVYENRFGFTDALRKMGATIQVYRECLGGLECRFGQRNFFHSAVISGPTRLRAADIEVPDLRGGFSHLIAALAAEGTSHVRGIELIDRGYENFTGKLEALGAKIVRD
>NZ_CP042828.1|WP_168211580.1|1864629_1866561_-|hypothetical-protein
MDENPTSAAMSRKAFLRIGGLGVGALAATSAWSPTGAAHADSGAGATAGAAPPGGAPGAAAAGTGGPILAGDHFPIGLFWPPPPLETTVERYEEIAAAGFTFVHGGNYTYADTQINHHLLAVAEQAGLHVLVDDPDIRWLLHQFSFGDSSEPFTLSEEEARQKIAEVTARYAPHWQTSGGRLLITGGSSEGSIGWVEDGTDWDDYTIAFSAEPRWTGAGGYAQAGWAFRVQDEANAYVWLLSSQGTDGNAVLKKAVFAGGTPTVTSTDLAFQLVEGQSYQIQTVLDADSIVTSIDGEVIDRSTDATFASGSAGFRQAGPESAFFDDLRVSAADGAELFAEDFTGDLSAWHRPAGSGRTSFAGLHLYDEPRETKFAQLASAVTAANEAYPDALAYINHFPNGVPEFNDGAAYRRAAEEIDTPVLSFDRYPILADGEDTGYFENLAQVREAALAHDRLPWVFIQSVGYAGHAVPTEDDLRWQISISLAYGYKGVQYFTYWTPDPARGEDFHEGLISVGGRRTGLYRAAQRVNTDFLAPLGAELLPLTSTSVQLAGADEIPAGLAQFEPDEDVTAATGDPVVLGRFTGAEHRYVLLANYSREQLARTHLTFGGGTAERFEPRTGQYRSARERIRLAPGGAELLRFG
>NZ_CP042828.1|WP_147916711.1|1866585_1867479_-|SIS-domain-containing-protein
MHQGSGTAGILTRLRFLLPELPDSLRITAEHILNDPRGAVSGTIGDLARAADTSTGAVSRLCRRLGLDGYPALRIAVAEDSGSRSAEHWNVDVSRGIDPGAPLTDVVRTLEAVQARAVHDTLAALDLPAVTALARAIGTARRVHVYGVSGSAIMARELALRLSRIGVPCWTYADVHDGLAGAAQLSDTDAALAVSHSGHTAETLAMLQCANEQGATTAVITSAHRSPLADLAEHVLLTTGTQTLFQDGPLAARHAELAVIEVLYVAVGQLTYERTVDHLARTAQAITDHRRDRPTIP
>NZ_CP042828.1|WP_147916712.1|1868020_1868527_+|hypothetical-protein
MIFDFITDLFVSLTQFVLGLDSWQQVAALILVGAIPFIESYLGSFLGVLVGIDPFFAVPAAVLGNLLCTFVLIATTSRVRAAATRNSRPEGTPQPTGRKQKVAKYLDRFGVPGVALLGPIVVASQITAPTLIALGATKRSVYLWVGISILGWGVAFGFFGNTLAGALQ
>NZ_CP042828.1|WP_147916713.1|1868606_1869830_+|sensor-histidine-kinase
MSRSAPVRLRGWAGGSDPERFEAYNRWSLLGLLAMGPVAQIVLGLGVPAPPAGIVASVAAWGYVLVSLVQLVAAGFFFARGLDAYLGRGQWRGRYLGVLVAATSVLVLLALGNAWFVPGTSVWMVVLPAGTALASLASVLTIRQLLLGTGAVLLLGAVTLAIAEDVRASGPGLAAAAVVLVTVVCSFRGSVWMTGVVWEQERRREVDARLAVAEERLRFSRDLHDIFGRTLSTVAVRSELAAELARRSDPRGAQTMLEVRQIAQDALKEVRGVVEGYRRVDLATELVGAQDILRAAGVRTSVTSPEAEVPTPAAEALGWVVREAVTNVVRHADATTCQITVTLTDDLVGVQVRNDGVRPAGPSSSTGSGLTGVTERLAALGGTLHSRSDAGEFTVTAQVPRSPRSSR

Crispr_ID: NZ_CP042828_6

• CRISPR_ID: NZ_CP042828_6
• CRISPR_location: 1953172-1953246
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_6

Consensus_repeat	Method
CCGGAGGAGACCGCTTCCGCTGAA	CRISPRCasFinder

spacers of NZ_CP042828_6

>6.1|1953196|27|NZ_CP042828|CRISPRCasFinder
GCGTCGAGCGGGGCCAGTCGCGCGGAG

CRISPR arrays and Neighbor proteins around NZ_CP042828_6

CRISPR arrays

The CRISPR arrays of NZ_CP042828_6

>merge|NZ_CP042828|6|1953172-1953246|CRISPRCasFinder
CCGGAGGAGACCGCTTCCGCTGAAGCGTCGAGCGGGGCCAGTCGCGCGGAGCCGGAGGGGACCGCTTCCGCTGAA

>NZ_CP042828|6|5|1953172-1953246|CRISPRCasFinder
CCGGAGGAGACCGCTTCCGCTGAA	GCGTCGAGCGGGGCCAGTCGCGCGGAG
CCGGAGGGGACCGCTTCCGCTGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147916766.1|1942912_1944100_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224050
NZ_CP042828.1|WP_147916769.1|1947702_1948746_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|238528
NZ_CP042828.1|WP_147916779.1|1958936_1959434_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP042828.1|WP_147916775.1|1953813_1954218_+|ribosome-silencing-factor	unknown	unknown	gnl|CDD|376779
NZ_CP042828.1|WP_147916783.1|1962926_1964039_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176193
NZ_CP042828.1|WP_147916765.1|1942133_1942916_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224095
NZ_CP042828.1|WP_147916768.1|1944805_1946611_-|glutaminase-A	unknown	unknown	gnl|CDD|377427
NZ_CP042828.1|WP_147916771.1|1950357_1951104_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238141
NZ_CP042828.1|WP_147916776.1|1954214_1954862_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP042828.1|WP_147916780.1|1959430_1960072_+|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl|CDD|223427
NZ_CP042828.1|WP_147916777.1|1956541_1957342_-|TSUP-family-transporter	unknown	unknown	gnl|CDD|376667
NZ_CP042828.1|WP_147916772.1|1951483_1952125_+|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl|CDD|234611
NZ_CP042828.1|WP_147916778.1|1957426_1958185_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|380379
NZ_CP042828.1|WP_147916782.1|1961602_1962907_+|MFS-transporter	unknown	unknown	gnl|CDD|340870
NZ_CP042828.1|WP_147916781.1|1960203_1961553_+|phosphonoacetate-hydrolase	unknown	unknown	gnl|CDD|131388
NZ_CP042828.1|WP_147919408.1|1946640_1947189_-|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|214900
NZ_CP042828.1|WP_147916770.1|1948836_1950150_+|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|234685
NZ_CP042828.1|WP_147916767.1|1944096_1944741_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224095
NZ_CP042828.1|WP_168211712.1|1951256_1951418_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147919409.1|1964094_1965552_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143415

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147916766.1|1942912_1944100_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl|CDD|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	9.89267e-146
NZ_CP042828.1|WP_147916769.1|1947702_1948746_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|238528	cd01095, Nitrilotriacetate_monoxgenase, nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2.	7.31639e-09
NZ_CP042828.1|WP_147916779.1|1958936_1959434_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	7.79033e-25
NZ_CP042828.1|WP_147916775.1|1953813_1954218_+|ribosome-silencing-factor	gnl|CDD|376779	pfam02410, RsfS, Ribosomal silencing factor during starvation. This family is expressed by almost all bacterial and eukaryotic genomes but not by archaea. Its function is to down-regulate protein synthesis under conditions of nutrient shortage, and it does this by binding to protein L14 of the large ribosomal subunit, thus acting as a ribosomal silencing factor (RsfS) by blocking the joining of the ribosomal subunits. This family is structurally homologous to nucleotidyltransferases.	2.57996e-41
NZ_CP042828.1|WP_147916783.1|1962926_1964039_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176193	cd08231, MDR_TM0436_like, Hypothetical enzyme TM0436 resembles the zinc-dependent alcohol dehydrogenases (ADH). This group contains the hypothetical TM0436 alcohol dehydrogenase from Thermotoga maritima, proteins annotated as 5-exo-alcohol dehydrogenase, and other members of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. MDR, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	5.97893e-124
NZ_CP042828.1|WP_147916765.1|1942133_1942916_-|ABC-transporter-permease-subunit	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	3.55572e-55
NZ_CP042828.1|WP_147916776.1|1954214_1954862_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.28215e-56
NZ_CP042828.1|WP_147916771.1|1950357_1951104_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238141	cd00229, SGNH_hydrolase, SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	3.94757e-13
NZ_CP042828.1|WP_147916768.1|1944805_1946611_-|glutaminase-A	gnl|CDD|377427	pfam04960, Glutaminase, Glutaminase. This family of enzymes deaminates glutamine to glutamate EC:3.5.1.2.	4.42303e-138
NZ_CP042828.1|WP_147916780.1|1959430_1960072_+|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl|CDD|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	2.49201e-42
NZ_CP042828.1|WP_147916777.1|1956541_1957342_-|TSUP-family-transporter	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.79125e-08
NZ_CP042828.1|WP_147916772.1|1951483_1952125_+|nicotinate-nucleotide-adenylyltransferase	gnl|CDD|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	2.19507e-100
NZ_CP042828.1|WP_147916778.1|1957426_1958185_+|helix-turn-helix-domain-containing-protein	gnl|CDD|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.49895e-31
NZ_CP042828.1|WP_147916782.1|1961602_1962907_+|MFS-transporter	gnl|CDD|340870	cd17312, MFS_OPA_SLC37, Organophosphate:Pi antiporter/Solute Carrier family 37 of the Major Facilitator Superfamily of transporters. Organophosphate:Pi antiporters (OPA) are integral membrane proteins responsible for the transport of specific organophosphates or sugar phosphates across biological membranes with the simultaneous translocation of inorganic phosphate into the opposite direction. The OPA family is also called solute carrier family 37 (SLC37) in vertebrates. Members include glucose-6-phosphate (Glc6P) transporter (also called translocase or exchanger), glycerol-3-phosphate permease, 2-phosphonopropionate transporter, phosphoglycerate transporter, as well as membrane sensor protein UhpC from Escherichia coli. UhpC is both a sensor and a transport protein; it recognizes external Glc6P and induces transport by UhpT, and it can also transport Glc6P. Vertebrates contain four SLC37 or sugar-phosphate exchange (SPX) proteins: SLC37A1 (SPX1), SLC37A2 (SPX2), SLC37A3 (SPX3), and SLC37AA4 (SPX4). The OPA/SLC37 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.95522e-88
NZ_CP042828.1|WP_147916781.1|1960203_1961553_+|phosphonoacetate-hydrolase	gnl|CDD|131388	TIGR02335, phosphonoacetate_hydrolase, phosphonoacetate hydrolase. This family consists of examples of phosphonoacetate hydrolase, an enzyme specific for the cleavage of the C-P bond in phosphonoacetate. Phosphonates are organic compounds with a direct C-P bond that is far less labile that the C-O-P bonds of phosphate attachment sites. Phosphonates may be degraded for phosphorus and energy by broad spectrum C-P lyase encoded by large operon or by specific enzymes for some of the more common phosphonates in nature. This family represents an enzyme from the latter category. It may be found encoded near genes for phosphonate transport and for pther specific phosphonatases.	1.2001e-153
NZ_CP042828.1|WP_147919408.1|1946640_1947189_-|flavin-reductase-family-protein	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	1.81155e-37
NZ_CP042828.1|WP_147916770.1|1948836_1950150_+|glutamate-5-semialdehyde-dehydrogenase	gnl|CDD|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
NZ_CP042828.1|WP_147916767.1|1944096_1944741_-|ABC-transporter-permease-subunit	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	6.81089e-56
NZ_CP042828.1|WP_147919409.1|1964094_1965552_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143415	cd07097, ALDH_KGSADH-YcbD, Bacillus subtilis NADP+-dependent alpha-ketoglutaric semialdehyde dehydrogenase ycbD-like. Kinetic studies of the Bacillus subtilis ALDH-like ycbD protein, which is involved in d-glucarate/d-galactarate utilization, reveal that it is a NADP+-dependent, alpha-ketoglutaric semialdehyde dehydrogenase (KGSADH). KGSADHs (EC 1.2.1.26) catalyze the NAD(P)+-dependent conversion of KGSA to alpha-ketoglutarate. Interestingly, the NADP+-dependent, tetrameric, 2,5-dioxopentanoate dehydrogenase (EC=1.2.1.26), an enzyme involved in the catabolic pathway for D-arabinose in Sulfolobus solfataricus, also clusters in this group. This CD shows a distant phylogenetic relationship to the Azospirillum brasilense KGSADH-II (-III) group.	7.07898e-177

Protein sequences

>NZ_CP042828.1|WP_147916772.1|1951483_1952125_+|nicotinate-nucleotide-adenylyltransferase
MISSERTPTRVGIMGGTFDPIHHGHLVAASEVADEFDLDEVVFVPTGAQPFKLDRPVTLAEHRYLMAVVATASNPRFGVSRVDIDRPGVTYTIDTLRDLQGEYPNAELFFITGADALGQILSWKDVDELWQLAHFVGVTRPGHRLDTENLPSGEYSLHEIPAMAISSTDCRERVRAGKPVWYLVPDGVVQYIGKHGLYKDPATFHQGPKEVQV
>NZ_CP042828.1|WP_168211712.1|1951256_1951418_+|hypothetical-protein
MSSSLLTVAAESGEHAAQGLSPIGFGVVTFAILVSLLLATLALRSLSTRHRKR
>NZ_CP042828.1|WP_147916771.1|1950357_1951104_+|SGNH/GDSL-hydrolase-family-protein
MARPVRSARQRRLPTPPALVLLLGLLWALAGCSSPGTEGESASSGTEQTTGAEQTTGTDAATGSDQDELSIAVVGDSITQASATTFAPGELSEDSWVSYAVGDPIELAGGWARWGATTAEMAAHAGPVDADVLVILAGTNDLAVGTETGQVAADLQRIADTVGADQVLLCGVPPIDARPEVVPPFNEFLTETAEANGWAWVDPAAGIRTDGTFAPGMSVDGVHPTQAGATQIGTEVREVLLAEFGSPG
>NZ_CP042828.1|WP_147916770.1|1948836_1950150_+|glutamate-5-semialdehyde-dehydrogenase
MSVQTDQRPGTDEGEEQQAQAGVQELAVQARAAARALRSATTATKNTALERIADALVAAAPQIIAANAIDTQRESDAGMSPGLVDRLRLDEARIAGIAQAVRELAALPDPVGEVVRGQSLPNGLTVRQTRVPMGVVGMIYEARPNVTVDAAGLALKSGNAVLLRGGSAAQESNAVIVAVLREALESTGLPAAAVATVDPYGRAGARALMRARGLVDVLVPRGGSGLIQTVVRESMVPVIETGVGNCHLYVDAAADLEQALPILINAKTQRVGVCNTIETLLVHEQVAAEFLPSALAALTAAGVHIHGDEATAALLRADATFSPATDEDWGTEYLSLDLAVRVVPDLDEALEHIRTWSSGHTEAICTTDLRAVQRFTTELDSAALMVNASTRFTDGGQLGLGAELGISTQKLHARGPMGLAELTTTTWIVQGDGHVRP
>NZ_CP042828.1|WP_147916769.1|1947702_1948746_+|LLM-class-flavin-dependent-oxidoreductase
MAFTRSHLSETRTDSVATEPAPAAQPRAARLARSRQQTSLIALDLSGAGAPREWRRAADSDAESFIMGRLAGLASLADNGGVDLITLDETFHAAGLRRRDDWLDGAVAASRLSRHTTAATLVAAVPLGRSRADHVAGAIASVHRASAGRAGWQLETGGGLAPRAVDSVISAWGERSARPQVVVPVRDAVDGELAAARADVARLSVATFEEAHAARTAIRQAAADWGRDPDEIRVLVDVQTVVSADRPSARARWDLLTSLETLPRAVPLRSLGTAADLADLWSSWVHRGGADGFTVIPASVPTDVAALVHEVVPALQARGLRKPRRAAVDRPATTRRTAARATARARV
>NZ_CP042828.1|WP_147919408.1|1946640_1947189_-|flavin-reductase-family-protein
MSESDSARGGTAPETAGAPGDQLAGEDFKRVFRQHPAGVAVITLAAEHGPVGFTATSVISVSATPPMLAFAIASSSSSWQALRQADTVLVHFLDAASAHLSAQFARRGTDRFAGVAAERLPGGEPLLTDAAAWLRARVVDRVRTGESHLVTLHALEAQIDRAERPLVYHDRTYHGIGAHTRL
>NZ_CP042828.1|WP_147916768.1|1944805_1946611_-|glutaminase-A
MESPITAYLHQLHDQIAQLREGTPYRIGARGAVDPDDFGIALATVDGYVYQVGTTSKEFSLQSLSKPLSYGLVLADLGIESVDAKIDVEPSGDPFNEISLDPETGRPANAMINAGALAVVSMIKGSGGRSAIQRIDETYAAFAGRRLRRSTRAYQSELRNSDRNHALAYLLSSVGIIESRPTAALETYLRQCTVQVTCRDLAMIAATLANGGTNPETGAEALSIEAVERVLSVMMTAGMYDDAGDWVSNVGMPAKSGVGGGVIAVLPGQAGLAVYSPPLDPHGNSVRGVATCRRVSRDMEMHFVRAARAGRSAIRSHHTIDREPSKTRRTEEASEILAEHGHRAVVIELAGDLYFAGTESVVRELSGLADDVEFVVLDVHRLDEVSRVALDMLRRIAEQFAAEGRRLILVDPDELLTPALSAETVATFDSRELAIAHCENQLLLRYGTPDSQRARVPVMDSPALSLLEAEDITALTALMHLRSYADGDVIRRVGQRFGGVFFILTGRILTIATDAGGNRVPVATLTAGMTFGDLALGEEDRQETTAKADGPVELMLLDAETIETLEQARPRLAVQLWRALARDAYAHAEQYARTVAARVSH
>NZ_CP042828.1|WP_147916767.1|1944096_1944741_-|ABC-transporter-permease-subunit
MEFLDFLVNRSDDMLELGLGHAGVVAISVLFASVLGIALGVLTYQRQRARDLVLATTGAMLTVPSFALFILLLGPLGLGARPVIVALTMYGLMPIVRNTVTGLNSVDPAVIESAKGMGLTRWQRLRQIELPLAWPVIITGIRVTTLVLLGICAIGAIVNGPGYGNLIFTGLARVGTPVAVHLVLAGTLGVIILAVLFDLLFYTARRLTTSQGIR
>NZ_CP042828.1|WP_147916766.1|1942912_1944100_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MTQTPAAGDDVMIRLEGLTKRYPGQQRNAVDALDLDIHRGEIVVLVGPSGCGKTTTMKMINRIIEPTAGRILLGGEDVTTTNADRLRRRIGYVIQQIGLFPHMTIAENIATVPKLLGWDATRIRARVDELLRMVNMAPEEYRSRYPKQLSGGQQQRIGVARALGADPAVLLMDEPFGAIDPITRDRLQNELLRLQAEVRKTIVFVTHDIDEAIKLGDRIAILQEGSRIAQYDTPEQILTAPANDFVADFIGRGASLKRLNLTHVADIELRAWPTVSYDTDAEAALEQLRTVPESALLVLDAQGSPVSWVSAEDLRRGAGRRLDEIGLPTNPAVEPRATLSDALNELITARYSVTIVVDDDGVFQGVVDIDQITDAIRSMRAAAVTEARAGLQESP
>NZ_CP042828.1|WP_147916765.1|1942133_1942916_-|ABC-transporter-permease-subunit
MSTGAPTRALVTQTPEAKSRRSWGGYLVMPAILALTCAALYLWVASKDLDSIEARALSADRLTAAIWQHIQLAAVSTVLTLIIAVPLGVVLTRPFARRIQPYLITLLTLGQAVPTIAILVLLAVAFLFLGFQAAIVGLVLYAIVPVLLNTMVGLEQVDSSVLEAGRGMGMSKFTVLRRLELPLAVPVILAGIRTALVINVGTATLVTYINAGGLGDIIVAGMTTNRFTVQVVGAVLTAVLALTIDYLAGLAEDVLRPRGL
>NZ_CP042828.1|WP_147916775.1|1953813_1954218_+|ribosome-silencing-factor
MPADDRSRHLAVVAARAAADLKAREVIALDVSERLVLTDVFVVTSGSTERQVRAIVDTVEEAMHAEGVKALRREGVTEGRWVLLDYGDIVVHVQHDEDRVFYALERLWKDCPVVELPEDARGASGESGESTAEA
>NZ_CP042828.1|WP_147916776.1|1954214_1954862_+|histidine-phosphatase-family-protein
MSASTVLLWRHGQTDYNAGGKLQGQVDIALNEIGRAQAAAAAEVLMRVQPVRIVSSDLSRAHATAQSLAERVGIDVHLDERLRERGFGEWEGLTHPEIAERWPEQFQVWTGGGHPDGVGAETRGGTGQRLAAAVREQAAAMDGGVLVVTSHGAAISSGITSLLGLDAEDWRGITGLGNCHWSVLRENPGSEPDWRLTAHNVGLEGPDFTHGPSIR
>NZ_CP042828.1|WP_147916777.1|1956541_1957342_-|TSUP-family-transporter
MTVLALILIGILTGLTTVLFGFGGGFVTVPVIVWADAAAGGAAGTVAVATSAVVMVINASVATSSTHRSTLARLRGRLPLLFLLALGGLLGAILALAVPAEITSWGFVLYLTLTIVDVLARPGFLRPAGHAKGASTRIAIPTVLGTPIGAVAAFLGVGGSVMTVPVLRRSGLPMGQATALANPLTLTISVPASLVFLAAQHTADIHGAVFAVGIVDLGAAALLLLGAVPVIVALRRRPPRIRDGAHAWTYVGLLLLVLVAMLASLI
>NZ_CP042828.1|WP_147916778.1|1957426_1958185_+|helix-turn-helix-domain-containing-protein
MRNVKLAEVDALPAAVLPIATVYPPDHLLIWHEHRRAQFLCAATGTMQVETDEGAWTVPTERAVLIPPHTRHQVQMLGVETNSLYIDPAAVPEWPNACRVVEVGALLHELLRTAVDIDPRGEIGERDSTVLTLILHELSRLAEVPLHVPIPPEEPFGRLCRQYLAVPDLAVGNSQWAREAGMSERTLTRKFRDEIGMSPAAWRSRARLLAAIPLLRHQSVTDVAARLGYATPAAFSYAFTRAFHVAPSRLSR
>NZ_CP042828.1|WP_147916779.1|1958936_1959434_+|sigma-70-family-RNA-polymerase-sigma-factor
MNEPFEKAVQRHGATVLRVCRAVLGAGPDADDAWSETFLAALRSWPDLDEATNVDAWLVRVAKRKAVDIARKRARHAVPTGELPEQPSRAGIPGAGDHELWQAVAALPERQRLALAYHYLGGLAHAETAELIGGSAAAVRRAAADGIKALRQQPSFDEPRRGADR
>NZ_CP042828.1|WP_147916780.1|1959430_1960072_+|methylated-DNA--[protein]-cysteine-S-methyltransferase
MTEKTESGPGREERPGEGGPERLFPVSATELDRLHIRLVERAQDEELLDVAYRTIDSPVGPLLLAATAKGLVRVAYQREGFEAVLDTLATRVSPRVLESPARLDPVATELEEYFTGTRHSFDLALDHTLSTGFRQLVQRHLPQIGYGHTQTYQQVAALVGNPRAVRAVGSACATNPLPVVVPCHRVLRTDGSLGGYIGGLAAKTALLDLERAA
>NZ_CP042828.1|WP_147916781.1|1960203_1961553_+|phosphonoacetate-hydrolase
MTARTFTVNERTYTMPDAPVVVICIDGSEPEYHLEAIKAGRMPWLAKTLDASGSSWEAHCAMPALTNPNNLSIATGHPPAVHGISGNYIFDTETGEEVLMNDSRFLRVPTIFGAANDAGLDVVVVTAKDKLRQLLGAGVVESGPSLEGTGEFVAPRRTGICFSAEKADRATLAENGIENVLDLVGRPLPSVYSADLSVFALAAGVEILETRGADLMYLSLTDYIQHKHAPGTQAANDLYAEIDRYAAALDALGAVVVLTADHGMSAKTDASGAANVLFVEEEVRRILDSTDVEPGTDDLRVILPITDPYTVHHGALGSFASVYLPEGADRDATIAALREIPGVESALSREQAAETYALPADRIGDIVVLGTAATAVGRYAAWHDLSGLDAPLRSHGGLGELQIPFLINRRLPRPEQLSVPFGQPAYVHNYDAFWVATSLLTQHTAAPAA
>NZ_CP042828.1|WP_147916782.1|1961602_1962907_+|MFS-transporter
MSSTTQRPAQLQEVGERGYSRWKWRVLIGAMLCYLFFYTGRQTFGFAIPGIEEEFGVDKAALGWVSAAMLWCYAAGQAINGNLADKFGGRKLMTLGAILSTILNWATSLSIGVKSLGLFWGLNGYVQAMGWPSGGRVISNWWGPHERGRAFGFYTLAAGMASVLAFVSSTVIVEILDLVWRWIFRLPVLLMLVGGITFYLLARDNPHAARIKPPPSYADQAEKSETGTTQAKTGRSLDRYKAVLRNPKIIITGLAIGFQNSARYGLLIWVPVYFLGTNWEEAGAQGAINPAWISVALPVGMAVGALVNGQLSDRVFGSRRDRPIMIFMALGAVCAMTMFLAPLGTVAGIAVLFLTGFFVYGPQSSFWALCPDLAGKRLAGTATGIVNFFAYLFAGIGEPVIGAVMDHTGNTGLVFPIVAGACVASALMASLIRR
>NZ_CP042828.1|WP_147916783.1|1962926_1964039_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MTPRTTATTPTTEGSDLAQSGTAAIWSGTADRFAIEPVPLPELASGEVLVRTELATICGSDLHTINGDRDTPLPTVLGHEAIGHVLATGGGVLAADGRPVTAGDRITWTIGTSCGLCRRCRRGIGQKCEQVRKYGHEAMDEHWQFNGGFASLVHLIAGTGLVHLSEEVPAAVATPANCATATVTCAARRVDLASDDVVVVLGCGMLGLTAIAYAKDAGCETVIASDIDPERLKLASTVGASHTVAPDELAATTAAHGADVVIELSGNSHAVQSAFDLIGLGGRIALVGSVSPAPEISFEPSGYVRNLTTVVGSHNYRVDDLVEAVAFLERTPAQATLAGLVSVPYPLAEIETAVEAANSGAAPRVAVAPN
>NZ_CP042828.1|WP_147919409.1|1964094_1965552_+|aldehyde-dehydrogenase-family-protein
MDFAVEDHHVQNYVAGHWTPSSTGQTRPNLNPADTRDVIGEFTESGAADARAAIDAAEAAQADWDALGPIGRATVLTRAARLIEERIDAFAAAITREQGKRLSEARGEVTRGLAILEFHIGEARRMNGETTAAEEPRTMVLTFRRPIGVVGLITPWNFPLTIPIWKVAPALLSGCTAVLKPSPLTPLTAALLVQAFADAGVPTGVLNLIQGDREAGEALVADPRVAGISFTGSLPVGSAINRAGAGRLMRTQLELGGKNALIVLADADLDAAVEAIIHGAYGQSGQRCSATSRVIVDRAVHAELMARLTPRVESMVIGPGNQSDADIGPVVNDERHRACLAAIEGAIAAGATLAAGGGAAELDQTGYYIRATLLDDVAWDSELAQEEVFGPVLSVITCDGYQDAMRISNSVKYGMSGTIFTQNPSLMFQALQDFEAGMLHVNRPGVGAYSHLPHMGAKASQLGAPECSPEVWNFYTDLRSACIRY

Crispr_ID: NZ_CP042828_7

• CRISPR_ID: NZ_CP042828_7
• CRISPR_location: 2074346-2074419
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_7

Consensus_repeat	Method
CCCCGGGGTCGTGACTCTGCCACT	CRISPRCasFinder

spacers of NZ_CP042828_7

>7.1|2074370|26|NZ_CP042828|CRISPRCasFinder
GACTGGCCCTGTTGATGCTTCGACGC

CRISPR arrays and Neighbor proteins around NZ_CP042828_7

CRISPR arrays

The CRISPR arrays of NZ_CP042828_7

>merge|NZ_CP042828|7|2074346-2074419|CRISPRCasFinder
CCCCGGGGTCGTGACTCTGCCACTGACTGGCCCTGTTGATGCTTCGACGCCCCCGGAGTCGTGACTCTGCCACT

>NZ_CP042828|7|6|2074346-2074419|CRISPRCasFinder
CCCCGGGGTCGTGACTCTGCCACT	GACTGGCCCTGTTGATGCTTCGACGC
CCCCGGAGTCGTGACTCTGCCACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147916875.1|2072002_2074147_-|DUF222-domain-containing-protein	unknown	unknown	gnl|CDD|367155
NZ_CP042828.1|WP_147916867.1|2060918_2061530_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367559
NZ_CP042828.1|WP_147916876.1|2074804_2075269_+|hypothetical-protein	unknown	unknown	gnl|CDD|379475
NZ_CP042828.1|WP_147916885.1|2088218_2090309_+|hypothetical-protein	unknown	unknown	gnl|CDD|380146
NZ_CP042828.1|WP_147916884.1|2086587_2088222_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147919417.1|2069350_2071144_+|phosphoenolpyruvate-carboxykinase-(GTP)	unknown	unknown	gnl|CDD|235256
NZ_CP042828.1|WP_147916872.1|2067065_2067473_+|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl|CDD|239550
NZ_CP042828.1|WP_147916882.1|2083871_2085689_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_CP042828.1|WP_147916871.1|2065569_2066955_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224169
NZ_CP042828.1|WP_147916874.1|2071209_2071869_-|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239322
NZ_CP042828.1|WP_147916883.1|2085712_2086486_+|collagen-like-protein	unknown	unknown	gnl|CDD|189968
NZ_CP042828.1|WP_147916868.1|2061526_2062285_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224059
NZ_CP042828.1|WP_147916879.1|2078251_2080816_-|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|236599
NZ_CP042828.1|WP_147916870.1|2065307_2065547_+|WHG-domain-containing-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147916880.1|2080931_2081840_+|Ku-protein	unknown	unknown	gnl|CDD|238408
NZ_CP042828.1|WP_147916873.1|2067546_2069001_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NZ_CP042828.1|WP_147916877.1|2075481_2076321_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|237907
NZ_CP042828.1|WP_147916869.1|2062281_2065005_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|225669
NZ_CP042828.1|WP_147916878.1|2076381_2078283_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP042828.1|WP_147916881.1|2082024_2083875_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147916875.1|2072002_2074147_-|DUF222-domain-containing-protein	gnl|CDD|367155	pfam02720, DUF222, Domain of unknown function (DUF222). This family is often found associated to the N-terminus of the HNH endonuclease domain pfam01844. The function of this domain is uncertain. This family has been called the 13E12 repeat family.	2.2519e-15
NZ_CP042828.1|WP_147916867.1|2060918_2061530_+|PadR-family-transcriptional-regulator	gnl|CDD|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	4.64445e-12
NZ_CP042828.1|WP_147916876.1|2074804_2075269_+|hypothetical-protein	gnl|CDD|379475	pfam14110, DUF4282, Domain of unknown function (DUF4282). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 93 and 155 amino acids in length. There is a single completely conserved residue E that may be functionally important.	0.00107435
NZ_CP042828.1|WP_147916885.1|2088218_2090309_+|hypothetical-protein	gnl|CDD|380146	NF000535, MSCRAMM_SdrC, MSCRAMM family adhesin SdrC. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	3.7781e-11
NZ_CP042828.1|WP_147919417.1|2069350_2071144_+|phosphoenolpyruvate-carboxykinase-(GTP)	gnl|CDD|235256	PRK04210, PRK04210, phosphoenolpyruvate carboxykinase (GTP).	0
NZ_CP042828.1|WP_147916872.1|2067065_2067473_+|Rieske-2Fe-2S-domain-containing-protein	gnl|CDD|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	2.39133e-22
NZ_CP042828.1|WP_147916882.1|2083871_2085689_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.38497e-163
NZ_CP042828.1|WP_147916871.1|2065569_2066955_+|FAD-dependent-oxidoreductase	gnl|CDD|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	5.6261e-113
NZ_CP042828.1|WP_147916874.1|2071209_2071869_-|thioredoxin-domain-containing-protein	gnl|CDD|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	1.22974e-80
NZ_CP042828.1|WP_147916883.1|2085712_2086486_+|collagen-like-protein	gnl|CDD|189968	pfam01391, Collagen, Collagen triple helix repeat (20 copies). Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.	0.000524361
NZ_CP042828.1|WP_147916868.1|2061526_2062285_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	4.39108e-97
NZ_CP042828.1|WP_147916879.1|2078251_2080816_-|ATP-dependent-DNA-ligase	gnl|CDD|236599	PRK09632, PRK09632, ATP-dependent DNA ligase; Reviewed.	0
NZ_CP042828.1|WP_147916881.1|2082024_2083875_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.91431e-137
NZ_CP042828.1|WP_147916880.1|2080931_2081840_+|Ku-protein	gnl|CDD|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	9.57174e-111
NZ_CP042828.1|WP_147916873.1|2067546_2069001_-|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.07774e-13
NZ_CP042828.1|WP_147916877.1|2075481_2076321_-|LysR-family-transcriptional-regulator	gnl|CDD|237907	PRK15092, PRK15092, DNA-binding transcriptional repressor LrhA; Provisional.	7.67333e-40
NZ_CP042828.1|WP_147916869.1|2062281_2065005_+|FtsX-like-permease-family-protein	gnl|CDD|225669	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	8.43931e-07
NZ_CP042828.1|WP_147916878.1|2076381_2078283_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.94968e-71

Protein sequences

>NZ_CP042828.1|WP_147916875.1|2072002_2074147_-|DUF222-domain-containing-protein
MDFDDENIDPEDHSSGDESSASSSEEERPEPFVTLPVGPDVGLTEVVAAAQEVDQAQAAWRSGVSLSQRSDVIGAAAPGASLAGVLEAAAERAPADRDQATRVELIAACERQMAQLAGLQAKFAQELLDERGASSRTLTAVHDEISCRLATTSYAAGTIITRAGALEDSPRLRKGLASGEVSARKLDVIAAAVSDLDPGERAVLENYGCELAPTHTPPQLKKALAVAIIAADPTRAEQRHQREVRERHLTFEPAAHGMSWLGVYLPAEDGLNIFTCLNAQAAATSAEDERGIDARRVDALTTLFESIMAGGRLPDGTTLPTQHGQSPHIRFSITAPVLAGDDQTPALLHGYGPICAGTARQLAHRAGADSGGLASPALFGTSTTGPTTDTGVDAGRSSTSGSPCLAGADRNLAPNPEPTWAERCALANRLDHGATAEERDVIFGPAWPWPDQRVRDEDLAIWRALLDRPRLDRLQHVAESSAQPKGSDERQPKGQPGTKGEPGTKGEPGTKGEPGRDPMWNLLPPPRPTELPDGTDANELIAWAQRHHSDEAGLCSSVEDQLGLICAGSYAPSRRLRARIIERDQTCRFPTCQVPAWRCQLDHISAFDGSIPAWAQTVETNLQALCTHHHQAKTAGVFRVERDARTGVTTWYAPTGHIYTRSPEHADYTGVTRQLRQELRASCEDDTLTSAAAEMRSAAGKTSPWPRDDTDPPF
>NZ_CP042828.1|WP_147916874.1|2071209_2071869_-|thioredoxin-domain-containing-protein
MTAEPPITVDVWSDIACPWCFIGNRTLKQAIEQYDGEVTVRYHSYELAPDTPVDYEGSEVDFLVKHKGLPPEQVQQMLDQVTSTGAAAGATFHFDTVQHTNTLRAHQALHHAAQHGRQTELLERLFRAYFSEGRHIGRDADLAELAAEVGLNSERLLADLAAERYATDVQRDLNHAQQMGVRGVPFFVFEGQYGVSGAQSVETFTEVLAHVAAEVGTRA
>NZ_CP042828.1|WP_147919417.1|2069350_2071144_+|phosphoenolpyruvate-carboxykinase-(GTP)
MAAARDFVAAVAELTGPDAVVWCDGSEAERDRLTEELCQAGTLIRLDPELRPNSFLARSDPKDVARVESATFICSAEESDAGPTNNWRDPAEMRAELLRVFAGSMRGRTMYVVPFSMGPVGGPASKVGIEITDSPYVVVSMRLMTRMGEAAMDQIDGGAEWVPAVHSVGMPLVTDGAAVLPDVPWPCNETKYITHFPDDREIWSFGSGYGGNALLGKKCYALRIASVLARDEGWLAEHMLLIRLRHADGRQFHVAAAFPSACGKTNLAMLRSVLPEWTVTTLGDDIVWLRPGEDGRLWAINPEAGFFGVAPGTGAGTNPTAVDTLTHDVIFTNVALTDDGDVWWEGLTPEAPEHLIDWVGQDWTPEVGAETGRPAAHPNSRFTVSAAQCPMIDPDWDAGEGVPVDLILFGGRRASNVPLVTAAEDWEHGVFFGATISSERTAAAEGAVGELRRDPFAMLPFCGYHMGDYFGHWLSVGERLGDRAPRIAAVNWFRKGADGSFLWPGFSENARVLDWLLRLVDGEVTGRQTPLGVAPADGELQLDGLDLPAADLDELHRVDPAAWSEEADRCAGYFAQFGDRLPVAMSRQLAALRERMS
>NZ_CP042828.1|WP_147916873.1|2067546_2069001_-|helix-turn-helix-domain-containing-protein
MADEHTDPVTLGKRIRHFRSRGRLTLAQLAETTGTTASQLSHIENGRREPRLSLLQAIASTLGTSASELLEPAPPPDRRAALEIELHRSQSSPLFASLGAPAVRPSRTLPLPVLESLVALHRELGRRAAEAIATPEEARRANTQMRLDMRARGNYLPEIEELGEEVIRKAGYTSGALTHSTVSTLARSLGFEIIHVPDLPHSTRTVTDLENGRIYLPPASIPGGHGLRSLALQAIGHRLLGHTQPASYADFLYQRVEIAYFAATCLIPRSAALDFLLPRQRAKDLAIEDFRDAFGVTHDFAALRLTNLATSHLDMPVHYLRVGEDGALYKGYENDGVALPTDVTGAIEGQLVCRQWAARAAFARRTRTTEFHQYTDTPDGTFWCSTQTGSTSSGEFTITVGVPFAHAKWFRGRETKRRATSTCPEEGCCRRPDEALSERWQQASWPSAVSHAQILGPLPSGRFPGVDDTEVYRFLEANAPSEPT
>NZ_CP042828.1|WP_147916872.1|2067065_2067473_+|Rieske-2Fe-2S-domain-containing-protein
MSGCLARRQVLLATGAGAGVFALAACTEDTSSAEEPQSGVVLLSLNELEVGQAQVATTDDGVAVAVVRTGEEEVRAFSAICTHQGCEVRAEEEDLYCPCHGSRFALADGAVTAGPAEDPLPEVAVEIQQGNVVTR
>NZ_CP042828.1|WP_147916871.1|2065569_2066955_+|FAD-dependent-oxidoreductase
MTERADVVVIGMGPGGEHVAGELAADGLDVIGIEANLVGGECPYYGCIPSKMMIRAADALAEARRVNEVAGRAEVQPDLAPAAKRIRDEATTDWDDQIAADRFTEKGGRLIRGRARLVAPRTVEVGDEQIQARRAVVLNTGTSPAIPPIDGLDQVPYWTNRDAVRTTRAPESMIVLGGGPIGLEFAQVFARFGTRVSVVEAADRLLPGEEPAASEVIAQAFRAEGIEVLTGDGVASVRSDSQGIRVQVGARELVAERLLVAAGRDTGLGRLGLDAYGLDTSARTLDVDRFCRVLGVDGGPVEGLYAIGDVTGKGPFTHMSMYQAEIALAHLRGDESLDAEYHAVPRVTFTDPEVGVVGMSEAQARKQAVPVRSTSVQVPTSARGWIHGVSNDGVITLVAHAESGMLLGATSVGPRGGEVLGLLTLAVQQRLPVHALTRMIYAYPTFHRAVLDAAKQWLAEG
>NZ_CP042828.1|WP_147916870.1|2065307_2065547_+|WHG-domain-containing-protein
MAATGLLSASARQEAEWPCWAAVHGFAHLVSDGPLRSAPDVHRRRLAEATVDAIIDGVCAAPPARLRWPTPLAHVRIER
>NZ_CP042828.1|WP_147916869.1|2062281_2065005_+|FtsX-like-permease-family-protein
MRRWLARWRAALRIARRDAWRSKGRTVLVVLLMMLPVAAGTFVVGVLRSSTPTTATTISWEMGDTAQARLALPCAAEVRTPTKQDASGMGACGAGGADLGELTESELAAAVPSGDGVSPAAEAYLDLRTDQALIDGAQVLETDTSAVPGLLGEVTGHAVPAAGQVVLRSGVAERLQVGVGDSVELMLGEEPEAVQVVGIGTSTSRTAALLGPGTLPDGGAQPVWFVTGDAPVTWADVVQLNAIGLVVISRAVLNDPPPPAEVYGGMFGGIAGDGGRLAGTLLAVGGLVLLEIILLIGPAFAVGAKRSARSLALVASAGGEPADLRRIVLAGGVVAGLVAAVLGMLVGTAASLIVYAVLVDSQTPAANLVIPLWEPVAIGAIALVLGVAAAWFPARSASRADVVTVLAGRRGEQPARHRVAWIGLGLGALGVVLSIVAAVTSQPVLLAGGVIVLELGLVMAAGALVALAGRLAPRFGVAGRFALRDAHRHRSRTAPAVAAVLAAVAAATAGMIWITSHAQVQEQVWKPVAADGTGLLSLDEWGASAEALDEQYQQATEVISAAYPEAVIAPVQNLTRTDETAGPNPVAMPDPETECPDPALMGPDAADERCRVIPTISSGYNWAYSLVDDGTLVGSLGLAGADEAARALADGQVLTNDPDSIWPDGNVHVAFRGNGPEPVTEEIVVPAHLVDWSSFQFNLVLSLAAAEEVVAANEEWIATQPDIDAVEARLHVAPIGAAITGVDLTQADVDELNRHLSDVEPNVRIAVEGQMNQQNSGTTILIVMGLALFVALAATGLSVGLAVADSRADLATLAAVGASPRMRRRVTAAQAGVIAGIGTVTGVVTGLLLGYVLGLWQGTDANFGSMWQTVVPWLPIAVLFIALPLLASGAGWLFTRSRLPVRRRMAS
>NZ_CP042828.1|WP_147916868.1|2061526_2062285_+|ATP-binding-cassette-domain-containing-protein
MNAQAAPVLLTLERVTRIHGAGAQEVRALDAVDLTVRMGELVAVMGPSGSGKSTLLNLAGGLDTPTDGTVQLAKDTLSDLNAKGRAALRRRRIGYVFQDFNLIPALTAAENVALPRELDGLRSRRARREALAALADVELEDLADRFPDELSGGQQQRVAIARALVGPRRLLLADEPTGALDSITGEAVMRVLRARVDAGAAGLLVTHEPRFAAWADRTVFLRDGIVVDATEPDEPEYLLSAAGSGPRHRDGR
>NZ_CP042828.1|WP_147916867.1|2060918_2061530_+|PadR-family-transcriptional-regulator
MSVKQGLLALLSEEPMGVARLRKQFEARTGGTWPLNIGQVYTTVRRLERDGLVAYASDETAETDVDRYLLTDEGRAEADGWWQTPVRRGAPERDELVIKVALAATAPGVSVRDVVQRQRTETMRALRDLTKLAARIDPASPADLSWSLVLDNHIFTAEAELRWLDHIESRAERAAHAATDPSTASAEAPKAARTGRAKSRSRR
>NZ_CP042828.1|WP_147916876.1|2074804_2075269_+|hypothetical-protein
MPQGYGQASVPQTPHAPQGGYGQASAPQNPQGGYAQAPQQQPGGYAQAGGFASGGQYPTSGNPGLFDTSFAVSSTQRTAKLAYVAIIVVAGALALAGLFRAVAQFANVSFGGASVVLGGLASLLIYGAIGFAVLAVGRLVVDFFVQEDKKREAS
>NZ_CP042828.1|WP_147916877.1|2075481_2076321_-|LysR-family-transcriptional-regulator
MFDPVQLRTFLTISETLNFTAAAARLGISQPTVSQHVARLERAANRRLVQRDTHEVALTDNGQAMAGFARSILAAHDQAAAYFTGSAMGGRLRFGAADDLALTQLPRILREFRQLHPQVTVELTIAQSHVLHRRLLAGHLDLVFIKQNAGEGTGALVRRDRLTWVGLPQAPLADAGVVPLITYPNPSMSRDMATRALEQAGRTWRVTCTTREINGMLAAVRAGLGITVLAQSLVPTDLVVMPASSGLPALGDVDMVLVDNPNAPREPVEALTAAILGRH
>NZ_CP042828.1|WP_147916878.1|2076381_2078283_+|MFS-transporter
MALIGTIGWINDAVTPNVAGAPSSRYSRLHFSAGILVHSASSAPTCPPTATATDTTPDTATSDVTATELHTTSPTDTDTDTAVARNEAPAPTAPEPRSAPSAREARAQRIRSRRGNRPAKVRPSRRHRHLGVSSVRPTEPATPAAPATAADSSTPAEPSTPAEPSTPATPGSRTNAALRTAARGTASAIGPALATLSPRRAIPRTKAAPSSGVGLIDALKVGNYRRYAIAQLCTSTFGWAARVAQDWLMLELTGSAALVGLTVAMQFTPMLLFGLFGGVLADRYDRRTILTITQSLFGLFTLALGVLALAGVVQPWHVLASAFLGGMAIVVDNPARQAFVHEIAGPKLLRRAISMNTSIFQLGALIGPAVAAGLIAVVGSGWAFVVNALACAFAASLIHSMRREEMFPTAVVRRTKGQLRAGLKHVSEHPEILWACVLVGFVAVTGVNMATVLTAYAADVIDLGASGYGMLTSTLALGAITGALFAGRARRLRLRTLVAGAATLGVLQIVAALISSTALFLVVLYAIGATSLLYLTRSNTLVQTSADPAMRGRVLSLYVLINMGAQAASGLIIGWVCEWGGPHAGFAACAAGPLLGALVVGTILARRGQLRPVLRVRRRPGRGFIYLVRRPVG
>NZ_CP042828.1|WP_147916879.1|2078251_2080816_-|ATP-dependent-DNA-ligase
MASPTRTELDGRLLQLTSLDKVLYPATGTTKAEVIDYYLQVAGAMLPHSAGRPVTRKRWVDGVGTAAEPGAAFFTKNLDSGTPDWVVRADLQHSDHRSTYPLVNDRASLAWMAQMAALELHVPQWRFDSAGQVLGPDRIVFDLDPGSGVSLPEVAEVAVWVRDILTGMGWASVPVTSGSKGIHVYAALDGGPSADQVRAVAQELARSLEADHPDRVISRMKRAERAGKVFIDWSQNHPNKTTIAPYSLRGTLEPFAAAPRTWDELTDPGLRQLRPAEVIERLASQGDLMAPGLAGVAGPDALERYRGKRRAERTPEPVPDAVRISGEQVFVVHEHHARRLHWDLRMSYCGILTSFAVPKGLTADPATQHLAVQTEDHPLDYLTFSGTIPAGEYGAGEMYVWDTGTFEVHKWWLGKEIIVTLHGSESGPLAEHAPAKYALICTDPAERQWLVHAMKRGGAAQRATRSTSTRRTSTQPGTPRPASPAVAHSPDAPPGQPEPAPDQPEPAPAQASTAVAASANEPPAPAEPAPPPASPAVVRPMLATPGTPSDVAQDWAIEMKWDGQRVLARFEDGQVRLWARSGREITATYPELAAIDVHADSALLDGEVVALDDEGRPSFALLQPRMQASDAEVARAARRQQVHYLVFDVLEVNGQDLTRQTYTDRRDLLARLVEPSEHVQVPEAFDGDLAAALAASHAYGLEGVLAKYPGSRYLPGRRSSSWIKIKHTEAVDVVVCGWRPGRGERTGQVGSLLLAVPTETGELRYVGRVGTGFSSAQTRQWPQMFAPEEIDAPAVVDVPAADARDARWLHPVRVAEVVFGEWTPTGRLRHPRWRGWRDDLTPAEISPPAGGPDR
>NZ_CP042828.1|WP_147916880.1|2080931_2081840_+|Ku-protein
MRAIWKGAVTFGLVNVPVSVYSATESHDVRLHQVHDADGGRIRYQRKCEKCGEVVPFEHIDKAFTDGDASVVLTEDDLATLPAERSKEIDVLEFVPNDQVDPIMFGSAYYLAPSSTSSKPYVLLRRTLEETDRTAIVSFTLRQKTRLAALRVRGDALLLQTLLWADEIREPDFEGLDEAKISAKELDMSAKLVRSYEADFDPAAHTDEYQVQLRALLEEKLASGEVVQASTPEDEDSGGEVLDLMEALRRSVEASRSARGGTSKSSKGTGSKTGAGKKSKATNTGKTAAKRKTADASEDKTA
>NZ_CP042828.1|WP_147916881.1|2082024_2083875_+|ATP-binding-cassette-domain-containing-protein
MASLPPSTAVVATLARLYPFLRPALPWLIAGMLSALGASLCALAIPQVLEWAVNGPLLGSAADGDRSGVWSAVLLVLGLGVLEAGLVAARRAFILVPGTRVEASMRMALFRHLQDLPIAFHDQWPGGQLLSRSMADLGQLRRWMSFGLIMLVVNTTTIGVGVGLMVDMGGILGIAYLCGALPVVYFSYRFSTRFRRISRLSQDQTGDLATTVEESVHGIRVLKAFGRGREAYQSFSVQADELRSTELSKARTLGGFTFAITTISEAVLGACLLSGVWLVVDGQLSVGALLAFFATAAVVNGPVEQLGHLVSMTLYAKTAVDRYFEVLDTANELPDPKDPIRPEEPVGDLVFDDVHFQYPDEPTPDQAWRDPARPSEAPRTEVIAGVDLHVRPGETMALVGLTGSGKTTMISLVPRLFDVTSGTVTVDGVDVRQMSRRDLRELVSIAFEDATLFSSTVRENVLLGAPEGYRAEADLDRALTVAQADFVRDLPAGLDTTIGEEGLSLSGGQRQRLALARAVAARPKILVLDDPLSALDVATEEAVTAHLREELADTTTLVVAHRPSTVALADRVAVLAGGRITAVGTHRELLAGHPHYRFVISSLAEDNDAESEVATR
>NZ_CP042828.1|WP_147916882.1|2083871_2085689_+|ATP-binding-cassette-domain-containing-protein
MSAAASTPRGVADEENSYLDRARSKEVRQRSLRLLGSLLRPVRGLFGVTVVLVVIAQAAKVAGPALIAGAVDRGLPAAMDGEWGPAIGFGIAYVGCAVVAGGGTAGYIRFAANVSQAILLNLRQRVFRQTQRLSLEFHESYTSGRIISRQTADLEALRELLDNGITSLASGLLFMVFTGVSLFLMDWQSGLVLLVAVLPVWLVTRWFQKRSQVLYRISRVASARLIVNFVETMTGMRAVQAFRREKANNGVYGELTEDYRQNNARTMGLNGIYDPALQLIGNVTVAVALAIGSFRLLDGGIEVGTLLATLLYTKRFFQPVQQMGMFYNSFQSASAALEKISGLLEEVPSVRAAEHPVALPKASGHLRFDGVRFGYGEETVLPKLDLDIPSGQIIALVGQTGAGKSTVAKLVARFYDVNGGRITLDGVDLREVAPRDLRRAVVMVTQEAYLFSGTVRDNIALARPDAADEEIEAAARAVGAHDFITALPEGYDTDVNKRGGRVSAGQRQLISFARAFLADPAVLILDEATSSLDIPGERLVQRGLQTLLADRTALIIAHRLSTVAIADRVLVMSQGEVVEDGSPEELIGRAGRFAALHQAWQDSLV
>NZ_CP042828.1|WP_147916883.1|2085712_2086486_+|collagen-like-protein
MSTADPHQPETPGESGATGSSVRPGTPAAPGARGTSGTPAASGQPGTPSASGVPGTPGQAPEQPSPSRWKFGDGVPPVWLRRVTIGAGVVIVLVLLGVLGSIVLPGWWAGVVTGLVQGVSSAGILVGLVCGLVFTVIPASVIWLAVRSTWTWRTRLIVAASAAVVALPNVLTLVIDVGTTSSAVDARLDMVIGSPSFTGSTLVGVIIGLIAVVGGVLGWRWLRRSRAELRKVRGAQGKKSRGRSRASRSETDTTASG
>NZ_CP042828.1|WP_147916884.1|2086587_2088222_+|hypothetical-protein
MPWASVGAVLLLLSGCTGTTTVDPDPTSPPPEPQPAAVAQLPETESSLVAQTDPAALALDSSAEFFASARAVVLAPAEDQAAALRAASIGIALGAPVLLTGSQDAAIEAEIVRLGAETLIPVGSVDLDAVDVTSMNVQPAPEDTDGLAELFGTAVDGSFGDASAPEAEAVAQSIAALEPGQVYPGDSSAAVPSRSGHMPPLLHGEGIEGLHVLADGQDYQAVAVANARAAGGQVAIVSGDPRASVGAVSALGAPEAVVGYGTSFGDQDTFAWQAATAATGTELPGGGQLVFDSTRYVALYGHPGTPSLGVLGEQNTDETIDLAAERAADYADLTEDTVVPTLEVIVTVAAGSAGADGNYSTEFPAENFVELIEAAADAGQYVVLDFQPGRANFLDQVREYEELLEYPNVGIALDPEWRLAEDERPLQQIGSVRAREVNQVVNYLADFVQEHALPQKMVVLHQFQQQMIRGRDNLDLSREEVALLIHADGHGTPEAKRETWRDVRSGAPDGMHWGWKNFIDEDSPMLTPARTYRIQPQPDYVSYQ
>NZ_CP042828.1|WP_147916885.1|2088218_2090309_+|hypothetical-protein
MNSADKSPEEHPETTPTPEEHAEAEEHAEPEEHPETTPAPEEHPETTPALRHRVEWWHQLRPMTRRSIRAGIVVLVTGFVALVVGLLSAQYTGSLGPHEADYSVRLNDEIRVDMGPLGALIVDSPLPLRVGVNVQVKEIPVGLAAPGANPIAGLTSDLQGYTQFFANPEPAIREAAGGLITDALGRFTLLWSIQLLIVASARLAGHGLLRETMKNAMRQPGVAPLTMAVVVAVTLVPLVDATRSSGNVGRTSAVLDGTPLEDARITGRLAPIVDYYGGYVVDAIDKNSEFYVAAQANLVSVFEAERAAAAQASADEEGAETGAENTDTDTDPGTDSDTDTDSDTDADADADGHGLASADAADGQETDTNTDTDTNTGADSDALGGGENPTSAESASADQTQNDEPTTAGEPTAAGEETPSGDEGSAGAETAAAEEEPELITGVMVTDLHCNIGMAEVIGTAAAEFGADLIINAGDTVMAGTSVESYCVSAFADGFGDLPVVFADGNHDSRTTTEQEVEAGWIPLEGEPVEVAGLRFFGDNDPTISSLGQPTRPTREETVLEMGDRLAARGCELAEEGEQVDVLLVHSPYAGRQIIEAGCAPVSLSGHMHNQTGPRQLGLGTQYIGASTAGAAEGSPTIGPLTQPATITAIRWDPDTHLPVDYRIVTVGTDTSVVLSDWTPWPAQPTEFVSGQQTEE

Crispr_ID: NZ_CP042828_8

• CRISPR_ID: NZ_CP042828_8
• CRISPR_location: 2109634-2109722
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_8

Consensus_repeat	Method
TGAGTGTCGGGGCGAGCGCGGTCGTGCGCAC	CRISPRCasFinder

spacers of NZ_CP042828_8

>8.1|2109665|27|NZ_CP042828|CRISPRCasFinder
GGGGCGGTGCGCACGGGGCGAAGGGCG

CRISPR arrays and Neighbor proteins around NZ_CP042828_8

CRISPR arrays

The CRISPR arrays of NZ_CP042828_8

>merge|NZ_CP042828|8|2109634-2109722|CRISPRCasFinder
TGAGTGTCGGGGCGAGCGCGGTCGTGCGCACGGGGCGGTGCGCACGGGGCGAAGGGCGGTGAGTGTCGGGCGAGCGCGGTCGTGCGCAC

>NZ_CP042828|8|7|2109634-2109722|CRISPRCasFinder
TGAGTGTCGGGGCGAGCGCGGTCGTGCGCAC	GGGGCGGTGCGCACGGGGCGAAGGGCG
GTGAGTGTCGGGCGAGCGCGGTCGTGCGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147916909.1|2118500_2119040_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl|CDD|367091
NZ_CP042828.1|WP_147916908.1|2118044_2118305_-|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|178943
NZ_CP042828.1|WP_147916895.1|2102237_2103695_+|mannitol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223324
NZ_CP042828.1|WP_147916900.1|2108186_2109062_+|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|187578
NZ_CP042828.1|WP_147916898.1|2106600_2107188_+|hypothetical-protein	unknown	unknown	gnl|CDD|274935
NZ_CP042828.1|WP_147916911.1|2120514_2121294_+|3-oxoacid-CoA-transferase-subunit-A	unknown	unknown	gnl|CDD|224702
NZ_CP042828.1|WP_147919420.1|2104982_2106116_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274934
NZ_CP042828.1|WP_147916893.1|2099636_2100653_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224525
NZ_CP042828.1|WP_147916902.1|2109905_2112824_+|leucine--tRNA-ligase	unknown	unknown	gnl|CDD|234743
NZ_CP042828.1|WP_147916897.1|2106152_2106608_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP042828.1|WP_147916910.1|2119084_2120290_-|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|180261
NZ_CP042828.1|WP_168211933.1|2109067_2109517_-|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl|CDD|153102
NZ_CP042828.1|WP_147916899.1|2107191_2108118_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378976
NZ_CP042828.1|WP_147916894.1|2100880_2102302_+|glucuronate-isomerase	unknown	unknown	gnl|CDD|235087
NZ_CP042828.1|WP_147916906.1|2115029_2116406_+|competence-protein-ComEC	unknown	unknown	gnl|CDD|377126
NZ_CP042828.1|WP_147916896.1|2103824_2104865_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147916903.1|2112827_2113433_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147916904.1|2113564_2114062_+|pyridoxamine-5-phosphate-oxidase	unknown	unknown	gnl|CDD|132706
NZ_CP042828.1|WP_147916905.1|2114205_2115033_+|ComEA-family-DNA-binding-protein	unknown	unknown	gnl|CDD|213597
NZ_CP042828.1|WP_147916907.1|2116789_2117842_+|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl|CDD|236130

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147916909.1|2118500_2119040_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl|CDD|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	0.000791928
NZ_CP042828.1|WP_147916908.1|2118044_2118305_-|30S-ribosomal-protein-S20	gnl|CDD|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	3.49793e-27
NZ_CP042828.1|WP_147916895.1|2102237_2103695_+|mannitol-dehydrogenase-family-protein	gnl|CDD|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	8.38015e-117
NZ_CP042828.1|WP_147916900.1|2108186_2109062_+|NAD(P)H-binding-protein	gnl|CDD|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.44726e-51
NZ_CP042828.1|WP_147916898.1|2106600_2107188_+|hypothetical-protein	gnl|CDD|274935	TIGR04037, predicted_flavoprotein, LLM-partnered FMN reductase, CE1759 family. This family represents a distinct clade within pfam03358. That family includes enzymes such as the NADH-dependent FMN reductase MsuE. Members of the present family regularly co-occur in genomes, typically as gene pairs, with members of TIGR04036, a probable FMN-dependent member of the bacterial luciferase-like monooxygenase (LLM) family. At least one member, RF|YP_001509627.1 from Frankia sp. EAN1pec, is fused to the LLM protein. The function of these gene pairs is unknown.	1.65137e-57
NZ_CP042828.1|WP_147916911.1|2120514_2121294_+|3-oxoacid-CoA-transferase-subunit-A	gnl|CDD|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	3.62988e-94
NZ_CP042828.1|WP_147919420.1|2104982_2106116_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274934	TIGR04036, family_protein, putative luciferase-like monooxygenase, FMN-dependent, CE1758 family. This tightly conserved subfamily of the bacterial luciferase-like monooxygenase (LLM) family, with members showing > 60 % pairwise sequence identity, includes proteins from both species with and species without the ability to make coenzyme F420. Therefore, the like cofactor is FMN rather than F420. The presence of three members in Kineococcus radiotolerans SRS30216 and two in Saccharopolyspora erythraea NRRL 2338 suggest closely related (subfamily) rather than exactly conserved (equivalog) function. Gene neighborhoods around members are not conserved. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP042828.1|WP_147916893.1|2099636_2100653_+|substrate-binding-domain-containing-protein	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.05444e-93
NZ_CP042828.1|WP_147916902.1|2109905_2112824_+|leucine--tRNA-ligase	gnl|CDD|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP042828.1|WP_147916897.1|2106152_2106608_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.10233e-13
NZ_CP042828.1|WP_147916910.1|2119084_2120290_-|acetyl-CoA-C-acyltransferase	gnl|CDD|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	2.62397e-173
NZ_CP042828.1|WP_168211933.1|2109067_2109517_-|DNA-starvation/stationary-phase-protection-protein	gnl|CDD|153102	cd01043, DPS, DPS protein, ferritin-like diiron-binding domain. DPS (DNA Protecting protein under Starved conditions) domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Some DPS proteins nonspecifically bind DNA, protecting it from cleavage caused by reactive oxygen species such as the hydroxyl radicals produced during oxidation of Fe(II) by hydrogen peroxide. These proteins assemble into dodecameric structures, some form DPS-DNA co-crystalline complexes, and possess iron and H2O2 detoxification capabilities. Expression of DPS is induced by oxidative or nutritional stress, including metal ion starvation. Members of the DPS family are homopolymers formed by 12 four-helix bundle subunits that assemble with 23 symmetry into a hollow shell. The DPS ferroxidase site is unusual in that it is not located in a four-helix bundle as in ferritin, but is shared by 2-fold symmetry-related subunits providing the iron ligands. Many DPS sequences (e.g., E. coli) display an N-terminal extension of variable length that contains two or three positively charged lysine residues that extends into the solvent and is thought to play an important role in the stabilization of the complex with DNA. DPS Listeria Flp, Bacillus anthracis Dlp-1 and Dlp-2, and Helicobacter pylori HP-NAP which lack the N-terminal extension, do not bind DNA. DPS proteins from Helicobacter pylori, Treponema pallidum, and Borrelia burgdorferi are highly immunogenic.	3.45714e-41
NZ_CP042828.1|WP_147916899.1|2107191_2108118_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	7.695e-38
NZ_CP042828.1|WP_147916894.1|2100880_2102302_+|glucuronate-isomerase	gnl|CDD|235087	PRK02925, PRK02925, glucuronate isomerase; Reviewed.	0
NZ_CP042828.1|WP_147916906.1|2115029_2116406_+|competence-protein-ComEC	gnl|CDD|377126	pfam03772, Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. These proteins contain a highly conserved motif in the amino terminal transmembrane region that has two histidines that may form a metal binding site.	6.00646e-33
NZ_CP042828.1|WP_147916904.1|2113564_2114062_+|pyridoxamine-5-phosphate-oxidase	gnl|CDD|132706	TIGR03667, Rv3369, PPOX class probable F420-dependent enzyme, Rv3369 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	1.40666e-09
NZ_CP042828.1|WP_147916905.1|2114205_2115033_+|ComEA-family-DNA-binding-protein	gnl|CDD|213597	TIGR01259, ComE_operon_protein_1, comEA protein. This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation].	4.99095e-32
NZ_CP042828.1|WP_147916907.1|2116789_2117842_+|DNA-polymerase-III-subunit-delta	gnl|CDD|236130	PRK07914, PRK07914, hypothetical protein; Reviewed.	4.68792e-58

Protein sequences

>NZ_CP042828.1|WP_168211933.1|2109067_2109517_-|DNA-starvation/stationary-phase-protection-protein
MAVTDATSTVPTHLQATLVDLIDLSLQGKQAHWNISGPHFRSLHLQLDEVIADLRTWSDDVAERMAAIGSPPDGRADVVANSSEVDRLDGGVLATDKVLRQFEDRLQAASDRIKATLADLEADLLSQDILIEVSTGLDKHAWMFRAAAG
>NZ_CP042828.1|WP_147916900.1|2108186_2109062_+|NAD(P)H-binding-protein
MCWSHDRNHAGTPRPSTSTDPILVLSGTGKTGSRIVDRLRGAGHEVRPASRRSTPRFDWDDRRTWPGVLEGVSTVYLALPLTATPVAEFVDRAVASGVRRLVALSGRGADHWKNGFGREMLDLEHAVRTSGVQWSIVRASNFAQNFDEDVFYDLLVAGELALPVGGVPEPFIDVEDVADVAVTMLTSNDWVDRVVEVTGPEALTWDEAVATIARAAGREVRFTDIPPEEYPAVLRSQGVPAADVHALETMFAELRRGLLTEPTDGVHQVLSRRPGTFADYAVRTAAAGAWS
>NZ_CP042828.1|WP_147916899.1|2107191_2108118_-|helix-turn-helix-domain-containing-protein
MDALSSLLRGVRADGVVLSRPTASPPWALRVHSAASISLCTPMCRQGWLVIPGQPEPILLRPGDTVLVRGPVDFSFIDDVDSAIERTCTDLPSAGGQAVVIEDQAEAPEGSAALLVAEFPIDGAVGRRLLEELPPVLVVPADPSCGTTLDYIAAEIAADQPGQQVVLERLLEWVLVCSLRAWFDSPQVIAPAWYPAMSDPVVGPALRAMHGDHARPWTVAALASTAHVSRATLAKRFTELVGEPPLTYLTGWRMTLAADLLSEPGASVADVARRVGYADPFGFSAAFKRTRGTSPSEYRRPNASAAAG
>NZ_CP042828.1|WP_147916898.1|2106600_2107188_+|hypothetical-protein
MTDLPSAANAITVVAVSGGVGFPSSTRRLTDALLQAVEQAAGDVTVLTRTIEVRDLAVDVAHATVAGLPSPELDDALRAIEQADLVVTASPVFRGSYAGIFKSLWDLVDPVAMRGKPVLLGATGGSMRHQLVIDQVLRPLFAYFGSLIVPTGVYAATEDVDLGPRRAPELARRIEQAGADALRLVPARSTSSLSN
>NZ_CP042828.1|WP_147916897.1|2106152_2106608_+|MarR-family-transcriptional-regulator
MSARSAAVAWESLLRAQVHLMRQFEAAKDFRPLSSREYDVLFTLSGSGRPMRLRDLNTHVLLTQPSLSRMVDRLAAAGWVQRTVADDDGRGVVISLTPAGARLQQAIGRRHVRSIAARIDPVLTEDEQTTLAELTSRLKSAAPAPERKSDD
>NZ_CP042828.1|WP_147919420.1|2104982_2106116_+|LLM-class-flavin-dependent-oxidoreductase
MQFGIFTIGDVTPDPTNGRLPTEHERIKAMVAIAKKAEDVGLDVFASGEHHNPPFVPSSPTTMLGYVAAQTEELILSTATTLITTNDPVKIAEDYAMLQHLSDGRVDLMLGRGNTGPVYPWFGKDIRQGLPLTVENYQLLRQLWDEEVVDWEGRFRTPLNGFTATPRPLDGVAPFVWHGSIRTPQIAELAARYGDGFFANNIFWPKEHFQALIGLYRERYEYYGHGSADQAIVGLGGQIFMRKNSQDAVKEFRPYFDNAPVYGHGPSLEEFTDATPLTVGSPQEVIDKTLTFADSFGHYQRQLFLMDHAGLPLKTVLEQLDLLGEILPTLRAEFDKDRPAHIPDGPTHAARVEAAGGAVDLTPRMEIDPLSGSAVRR
>NZ_CP042828.1|WP_147916896.1|2103824_2104865_+|hypothetical-protein
MGTLVGHSAASLHARRTWRRRVARELAAEFGGVVHRRELRAVGISRDEVRSEVRGGRWIALGKHTVCIDAAGARHVAEPRPGAERSAVAGQRRLWRPTSPRAFAAWVVWETGSGTVLDGVSALLAGGLEGYTEERVFVTVPRGRRAVALAGVVRHTHRVVVRAPGAGLPRVRTEAAVVHAVEWAASERQAALIVILAVQQRLTTAERLVEEVSSRRRVRRREFLRRLLREVSGGVQALGELDFARLCREHGLPVPSRQRVCQGPRGRIYLDVWWEEFRVGVEIDGVQHYQGLRPVDDALRDNAVRLRRGPVLRIPSLGLLTDPDAFMAQVKEVLARAARSSDSGHR
>NZ_CP042828.1|WP_147916895.1|2102237_2103695_+|mannitol-dehydrogenase-family-protein
MKPTRRSTIWWSPTRRTSSSSEESVPVTQRLRRGLPGTPATSAPVRIVHLGVGNFHRAHQAWYTHHAPDAEDWGIAAFTGRRPDQAEALAPQDGLYSLITKGAGGDEVEVISSIVAVHPASEHETYLAYLAEVSTAVVSMTVTEHGYRRGADGHLDLAADDVAADVAALRSDPRAVVTSMPMRLLAGLLARREARGGKLTILPCDNLPDNGDVTRTLVIDAARAVDETLLDWISEHVDFATSMVDRITPATTDTDRELVVERTGYSDASPVPTEPFAEWVISGEFPAGRPAWDAAGVQFVADVAPHERRKLWLLNGSHSQLAYVGSVRGHETIDAAIADPACRGWVEQFWDEAQRGLGLPEAEVEAYRTALLDRYANPRVRHLLAQIAMDGSQKLPVRTLPAVSAERAAGRVPVGGATTLAGWVLHLRGAGAPVKDAGAGPAQEAANAGDLAEVVPAVLETLQPGLGRDAELVSAVVAQAQAITA
>NZ_CP042828.1|WP_147916894.1|2100880_2102302_+|glucuronate-isomerase
MSKPTPPLELHPDRLLPADPARRGVARALYESVKDLPIISPHGHVPPAWIADDTPFRDPTSLLITPDHYITRMLHAHGISLSDLGVGRGPLDEADARAAFRALCSHWSAYRGTPVRYWLEEELGGIFGVDVRPSADTADQIYDTIAARIAQPDFTARALMKSFNIDVLATTDDPCADLSEHARLAGDATFGHRVVPTFRPDKYLDPGLPDWNADADRLGQVSGEDTSTYAGFIAALESRRRYFVQHGAVSADHGVIDAVTVILDEGEASRIYAAARAGRVTEEESTALRRHLLTEMARMSCEDGLVMTIHPGVRRNHHTATFESYGPDVGCDIPIAVEYTDSLRPLLDAYGTHPNLHLVLFTIDETVYSRELAPLAGFYPSVYVGVPWWFIDAPEAIRRFRSAVTETAGFSRTSGFIDDTRAFCSIPARHDMSRRLDAGYLADLVLEHRLPEDEAHEAIHDLVVTNPTNVFKL
>NZ_CP042828.1|WP_147916893.1|2099636_2100653_+|substrate-binding-domain-containing-protein
MPESDESAAGAPPAVTIYDVAREAGVAPSTVSRAFSRPGRVNAETGERIRQIAERLGYRVKEQARAQSASRTGMLAVVLADLGNPVFYELVRGAGSACEAAGYTMLLAETAESAVRERATLERALGSVDGLVLTASRISDSAIRQVAKVKPVVVVNRVVPGVPSVVIDVERGTFKSVEHLVELGHEKVTYLSGPEASWADGMRWRGLRRAAEELGVRIRRTGPFAPTVNGGVEAAATWAQHRTSAVVAYNDMVAIGFIRGAGRLGARVPEDVSVVGFDNSAMAELVSPELTTVAAPLQALGQTAAKNVLAMIGGARSHAEEPMQLPTRLVVRESTARP
>NZ_CP042828.1|WP_147916902.1|2109905_2112824_+|leucine--tRNA-ligase
MTEPTAATAPATGDNPPHRYTAELAGRIEQSWQDRWAAEGTFHAPNPVGDLAEDSVRPEKFYLLDMFPYPSGKGLHVGHPLGYIATDVVGRFKRMTGANVLHALGFDAFGLPAEQYAVQTGQHPRITTEENIATMRRQLRRMGLAHDDRRTFATTDPEFVRWTQWIFQQIFNSWFDTDAPRRDGRGTGAARPIAELVDQFTAGTRATPTGQDWAELTPAEQEEILGTYRLAYVAHVPVNWCPGLGTVLANEEVTAEGRSERGNYPVFQRNLRQWMMRITAYGDRLVDDLDLLDWPEKVKTMQRNWIGRSEGAQVRFALGEPDAEPSSAVDVFTTRPDTLFGATFMVLAPENDVLDALVPAAWPAGTREAWTGGHATPAEALAAYRQAAAAKTDLERQAEGREKTGVFTGVYATNPVNQAALPVFLADYVLSGYGTGAIMAVPAEDERDYAFATRYELPVVRTVQPPADFEGGAYTGDGPTINSANEQISLNGLEREEAKALVTDWLSQRGTGTPTVTYRLRDWLFSRQRYWGEPFPVVYDTDDRPIAIPDELLPVELPEVPDFSPRTYAEEDANSTPEPPLARAEEWVNVTLDLGEGTKTYRRDTNTMPNWAGSCWYELRYLDPANTATFVDPENEKYWMGPQLDEDGQPTTGGADLYVGGVEHAVLHLLYARFWHKVLYDLGHTSSLEPFHKLFNQGYIQAYAYTDSRGVYVPADEVLEHPSDDGESTFTYQGESVRREYGKMGKSLKNMVTPDEMYAAYGADTFRVYEMSMGPLDDSRPWDTRAVVGAQRFLQRLWRNVVDEETGAVTVTDDPAGRETAQLVARTIAEVRTEMAAMRPNTAIARLIVLNNHLTGLGQVPRDAIEPLVLMTAPVAPHIAEELWSRLGHQSSLTYQPFPEADEELLVAETVTCVVQVKGKVRDRLEVAPSISEEELQALALAAPGVQRALDGAPVRKVIVRAPKLVNIVPGG
>NZ_CP042828.1|WP_147916903.1|2112827_2113433_+|hypothetical-protein
MAIGPIGPPPQVPLAEIGRSVRLLSAWGAGVGGGLLVLLAFVGISSYAVFGTGDQRSDPSDGSMFAGGEEFFAWLIGNLAAGFGIFVLGVTALVLDITVLAKLSRLRRYGVRTEMTRPLTVALVLGMGLVSTPAGLLLLLIPSMVFGPGQATDTALIVIVLLMLAVPVTGRIAQVNCARRLVGLLSGQHAGWTPAARPGSW
>NZ_CP042828.1|WP_147916904.1|2113564_2114062_+|pyridoxamine-5-phosphate-oxidase
MEPHEIAAILDRPASQELLARDVLRMAYVAKDGTPRNVPVSFTWNGAQIVVCTSTNAPKLRSLRHHPAVALTIDTEVHPPMILLLRGYAELDVVRGIPQEYLEMNGSYQMTPEQRVDWEAEVRSLYESMVRIVITPTWVKLIDFETTLPSAVEELVQQRAERQRV
>NZ_CP042828.1|WP_147916905.1|2114205_2115033_+|ComEA-family-DNA-binding-protein
MTAQRPRDRLRRLQLAAYEPAREAGGAQEADDGARHRAERSEGVRQRTSWALRPGTLARVALAVVLLGVLLAVAAVASGVLRLGAPGSPEVTPTQPTLPTPSAAPPASAAPSADGADSPGVGEVASAEAALYVHVAGAVSDPGLVQLAPGERVADAIAAAGGAAETADLDRVNLAAPVTDGEQVYVPAEGETPPALPEAATGSGASDAEVSAAVVNVNTAGAEELETLPGIGPARAADIIAHREEDGPFESVEDLLAVPGIGPATLDRLRERVRL
>NZ_CP042828.1|WP_147916906.1|2115029_2116406_+|competence-protein-ComEC
MSPLYPGAGLDLRLVPAAALVWLVCGWGVGVGENAGWAVVLGLLVAAAAGLRRLRGRVLARHRRSGNELLAAGVLALLVAALVLGTVAVRGSARAELVAELDGASPAVTVQLQREARPHEDGAIADALLLEVEGRAGELRAPVVLLGGPGWLDLPFGAQVRTSAQLVATAAGDDRVLLVIADSIGSVRAPDGWRAQVASIRAGLAELCADLPPAGRGLVPGIALGDTRALPAALAEDMRTVSLTHLTAISGAHVALLLAVLMVLLLWAPRWLRAGLGVVALVAFVALVRPEGSVLRAAVMGGVLLLGLVLRRPRSGLPALAVAVVVLIAADPWITRSYGFALSVLATGGLLLLAPPLATWLSRWLPTPLAAAIAIPVAAQLTCLPVLLLLQPSLPVYGVLANVLAAPVVAPATVLGVSAALLGPVAPTAAAACVQGASWCAEWIAVVARACAAIPGAG
>NZ_CP042828.1|WP_147916907.1|2116789_2117842_+|DNA-polymerase-III-subunit-delta
MPVPPSRRRPAASGPSWRDVPLAPVVLLRGSEGLLVDRASERLTALARQHAAAAQGLPEDAAPQVDIETPQIEAATYTRGNLDVIASPSLFGEHRHAVVVGAEAASDAFIEDALAYVAAAGHEIGDFTLVIRHEKGTRGKKLLDAIAKAGYPVVTCEPIKRDGDKVEFAGGEFTDAGRRATRAAVQALVEALGSDLRELASGCAQLIADSTGTITPDVVQKYYGGRVEATGFRVADAAVAGQTTEAVTLLRHALETGVDPVPLVAVLAMKLRALAKVSTVRGRGNPGDLGMAPWQVDRARRELRGWTPEGLATAITAVADADAQVKGEYRDARFAVERAVLRVCAARDGG
>NZ_CP042828.1|WP_147916908.1|2118044_2118305_-|30S-ribosomal-protein-S20
MANIKSQIKRNRTNEKARLRNKAYKSELKTHVRHVREAIASGDKESAESTLRDATKKLDKAVSKGVIHKNQAANRKSALAKQVAAL
>NZ_CP042828.1|WP_147916909.1|2118500_2119040_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSLLSSFARAARLVAREAVRSSRREARRASTRRQRSRPQGPSAGQRAHTYLGPLPPPEYAPVSDGAPDPGEVVWAWVPYEEDDSRGKDRPVLILAEHDDGLLGLQLTSKDHDTDAEQEARWGRYWVDVGSGAWDSQRRESEARVDRVLWLPLSAVRREGAALDRDRFTDAVAAVRRHRG
>NZ_CP042828.1|WP_147916910.1|2119084_2120290_-|acetyl-CoA-C-acyltransferase
MSDPAAVSDPADVVVIGAARTPFARLNGALASLPATALGAHAITAALAQAQLPGDEVDAVFLGQVLQAGTGQNPARQAALGGGVGPRAHASAINKVCLSGLSAVIDAARLIRSGEAQVVVAGGMESMSQAPHLLPGVRGGWTYGDRTAVDHLAYDGLTDAVEQISMGELTERGSAGFPGTDLSRTAQDAWAATSHQRAAAATAAGTFAAEIAPVKVRTRKAETEVSSDEGIRPGTTTESLAGLRPAFATGGAITAGNASQLTDGAAALVLTTRARAEAAGAPVLVAVRACGQVAGPDNSLHTQPANAIAQALDRAGWMPSELAHVEVNEAFAAVVLASIAALGIAADRVNPHGGAIALGHPIGASGARLAVHLAHTLQPGQRGAAGLCGGGGQGEALLLEG
>NZ_CP042828.1|WP_147916911.1|2120514_2121294_+|3-oxoacid-CoA-transferase-subunit-A
MSTTLSSGIDKVVRDPAEAVADIGDGASIAVGGFGLCGNPMVLIEALLAQGASGLSVVSNNCGVDDWGLGLLLRAERLAKMTSSYVGENKEFERQFLTGELEVELTPQGTLAEKLRAGGAGIAAFFTRTGVGTQLAEGGLPRRYHPDGSVAQASPAKETRTFGEHQYVLEEAISTDFALVHAARGDRAGNLVFNATARNFNPLAAMAGRICIAQVEELADIGGIDPNEVHIPGVFVHRVVPVGTDIEKRIERRTVAEEG

Crispr_ID: NZ_CP042828_9

• CRISPR_ID: NZ_CP042828_9
• CRISPR_location: 2561095-2561201
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_9

Consensus_repeat	Method
CGCCTCACTCCTCACAAATCTGTA	CRISPRCasFinder

spacers of NZ_CP042828_9

>9.1|2561119|59|NZ_CP042828|CRISPRCasFinder
CCTGTGACGATTTGCTTGCGGGGCTCGGCTACGCGGGACCTCGTTCCTCGGCCCCACTG

CRISPR arrays and Neighbor proteins around NZ_CP042828_9

CRISPR arrays

The CRISPR arrays of NZ_CP042828_9

>merge|NZ_CP042828|9|2561095-2561201|CRISPRCasFinder
CGCCTCACTCCTCACAAATCTGTACCTGTGACGATTTGCTTGCGGGGCTCGGCTACGCGGGACCTCGTTCCTCGGCCCCACTGCGCCTCACTCCTCACAAATCGTAG

>NZ_CP042828|9|8|2561095-2561201|CRISPRCasFinder
CGCCTCACTCCTCACAAATCTGTA	CCTGTGACGATTTGCTTGCGGGGCTCGGCTACGCGGGACCTCGTTCCTCGGCCCCACTG
CGCCTCACTCCTCACAAATCGTAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147917260.1|2558335_2559301_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917255.1|2553049_2553379_-|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380358
NZ_CP042828.1|WP_147919458.1|2564476_2566285_-|amino-acid-transporter	unknown	unknown	gnl|CDD|223605
NZ_CP042828.1|WP_168211759.1|2556313_2556844_-|Ig-like-domain-repeat-protein	unknown	unknown	gnl|CDD|379864
NZ_CP042828.1|WP_147917256.1|2554164_2554560_-|hypothetical-protein	unknown	unknown	gnl|CDD|370696
NZ_CP042828.1|WP_147917265.1|2566624_2567341_-|DUF4191-family-protein	unknown	unknown	gnl|CDD|379389
NZ_CP042828.1|WP_147917270.1|2570779_2572210_+|hypothetical-protein	unknown	unknown	gnl|CDD|270916
NZ_CP042828.1|WP_147917267.1|2568179_2569181_-|lipoyl-synthase	unknown	unknown	gnl|CDD|235493
NZ_CP042828.1|WP_147917261.1|2559489_2560899_-|mycothione-reductase	unknown	unknown	gnl|CDD|181142
NZ_CP042828.1|WP_147917266.1|2567395_2568049_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917257.1|2554742_2555129_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917254.1|2552241_2552820_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP042828.1|WP_147915652.1|2556971_2558054_+|IS110-family-transposase	unknown	unknown	gnl|CDD|226077
NZ_CP042828.1|WP_147917271.1|2572559_2573738_+|Cmx/CmrA-family-chloramphenicol-efflux-MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP042828.1|WP_147917268.1|2569357_2570008_-|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl|CDD|184638
NZ_CP042828.1|WP_147917258.1|2555347_2556166_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917263.1|2562779_2563184_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NZ_CP042828.1|WP_147919457.1|2553563_2553893_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_168211760.1|2570069_2570714_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010
NZ_CP042828.1|WP_147917264.1|2563272_2564442_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224172

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147917255.1|2553049_2553379_-|LuxR-family-transcriptional-regulator	gnl|CDD|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	3.48886e-22
NZ_CP042828.1|WP_147919458.1|2564476_2566285_-|amino-acid-transporter	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	0.000277875
NZ_CP042828.1|WP_168211759.1|2556313_2556844_-|Ig-like-domain-repeat-protein	gnl|CDD|379864	pfam16640, Big_3_5, Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold.	0.000421437
NZ_CP042828.1|WP_147917256.1|2554164_2554560_-|hypothetical-protein	gnl|CDD|370696	pfam09791, Oxidored-like, Oxidoreductase-like protein, N-terminal. Members of this family are found in the N terminal region of various oxidoreductase like proteins. Their exact function is, as yet, unknown.	0.000545148
NZ_CP042828.1|WP_147917265.1|2566624_2567341_-|DUF4191-family-protein	gnl|CDD|379389	pfam13829, DUF4191, Domain of unknown function (DUF4191).	5.72687e-95
NZ_CP042828.1|WP_147917267.1|2568179_2569181_-|lipoyl-synthase	gnl|CDD|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0
NZ_CP042828.1|WP_147917261.1|2559489_2560899_-|mycothione-reductase	gnl|CDD|181142	PRK07846, PRK07846, mycothione reductase; Reviewed.	0
NZ_CP042828.1|WP_147917271.1|2572559_2573738_+|Cmx/CmrA-family-chloramphenicol-efflux-MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.48513e-60
NZ_CP042828.1|WP_147917263.1|2562779_2563184_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.33982e-05
NZ_CP042828.1|WP_147917254.1|2552241_2552820_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	2.57122e-31
NZ_CP042828.1|WP_147915652.1|2556971_2558054_+|IS110-family-transposase	gnl|CDD|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.15964e-16
NZ_CP042828.1|WP_147917268.1|2569357_2570008_-|lipoyl(octanoyl)-transferase-LipB	gnl|CDD|184638	PRK14345, PRK14345, lipoyl(octanoyl) transferase LipB.	5.49239e-111
NZ_CP042828.1|WP_147917270.1|2570779_2572210_+|hypothetical-protein	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.16743e-28
NZ_CP042828.1|WP_168211760.1|2570069_2570714_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	5.62907e-45
NZ_CP042828.1|WP_147917264.1|2563272_2564442_+|FAD-dependent-oxidoreductase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	9.44406e-28

Protein sequences

>NZ_CP042828.1|WP_147917261.1|2559489_2560899_-|mycothione-reductase
MASPAPDIAVDARYDLIIIGTGSGNSIPGPEFDDRSIAIVEEGTFGGTCLNVGCIPTKMHVYAADVALETAQSGRLGLDAQVNAVDWPGIGTRIFDQRIDLIAAGGEAYRRGPETPNIDVYDQHAVFVGARTLRTGQGADEKIISGDQIVIAAGSRPFIPEAITASGVHYHTNDDIMRLPELPKSLVIVGGGFIAMEFAHVFDALGVEVTVVSRSPLLRHLDADLHERFNNLAAERFTVLRGRTVVGADESEQGVSVRLDDGATVTADVLLVATGRIPNGDRLDLAAGGIAMTDQGGVQVDQYGRSTTADGVWALGDVSSPYMLKHVANAEMRAVRHNLLHPEDLQAMPHEHVPSAIFTHPQIATVGLTEAEARGQGYAVTVKVQNYGDVAYGWAMEDTTGICKLVADRDTGKLLGAHYLGPQAATLIHQMITVLAFDLDVREVATKQYWIHPALAEVTENALLGLDFS
>NZ_CP042828.1|WP_147917260.1|2558335_2559301_-|hypothetical-protein
MSVPAKRHHLPRPARIAGTVAAAVAASMIVVPGAHAAPAPAPGQALAAPAITRDLTESPAVAEAVVSLQATEMVYGSTGELVAAVGTVDGDPVTSGTVSFLLNGRTLSADVVDGSASVPVTTADFGSVHGYPLNTGGYWFRATYTGEGHTDAEASAKLQVSPADPALEATIAPEAVPGEAVAIEGRLTAQPDHEGQPQGSLQLVVDGEPVGDPVRVGDDGGFVTEFTAPESWQPGEHTVELTLPRHGNFNAASFALTTTVNPATSETVVRVQDAEMVYGSTGELVAAVETVDGDPVTSGTVSFLLNGRTVSADVVDGSADM
>NZ_CP042828.1|WP_147915652.1|2556971_2558054_+|IS110-family-transposase
MFTERTSVGLDVHARSVVAAAIDGVTGEFFRTRLTPSHEEIRSWVNDLPGPAAVAYEAGPTGFGLYRHLMATGIRCEVVAPSKLQRPSGDRVKTDARDAVHLARLLRLDEFTAVRVPTVDEENARDLVRAREDARGDLMRARHRLSKLLLRHGLVYSDGRAWTGVHEAWLRRQRFESHALQLTYESDFEAVLTVQARRDRLNEAIAAMAADSEFTPIVRRLGCLRGIGDLTGLALAVEVGDWHRFTGNSIGSFVGLVPSEYSSGASRVQGSITKTGNTHVRRLLVEAAWHHRARYVIGKTIQDRWELAPPAARARGDAGNRRLHQRWNTFRERRKRHVVANVAIARELAGWCWSLAVLEE
>NZ_CP042828.1|WP_168211759.1|2556313_2556844_-|Ig-like-domain-repeat-protein
MPVTTADFGSVHGYPLNHGGYWFRATYTGEGHTGAEASAKLQVVKAPVELAAYPETDELEAGDSLTLDGRVTALEGNDGQPQGNLQVIVDGEPVGDPVRVTEDGSFSTEVTIPEGTAPGEYTIGLVYGESANFTEGSVELDLTVVAPEDAPESIWDFLQRMLRELLDWLGSLLGGR
>NZ_CP042828.1|WP_147917258.1|2555347_2556166_-|hypothetical-protein
MPDAQFSEFAYGYAVIREAEQLLTRLGAAITGAPVLPSLITENTVGYDANLVAVDFSLFLQFKRSFHVSALHPVGPCGSPGGRPHCTWAYWMKEHYRFAADTTSNQFHAMRGYEDAVALGYTAGLSVYTAPGFATNAELDQAYQSGAILDRSVAVLPSEFDAVSNGPHKYSFLPDLSRGVITSAPVRAGATPLDQLITDTVEARVPRVRDDAVSLQQWAAGLSERLADGQREPRDRLIRAAEEGATGPILQALRDTTGYLGGTVLMLGRHRP
>NZ_CP042828.1|WP_147917257.1|2554742_2555129_-|hypothetical-protein
MTTHRIRKTLTGVLASAALTTTALVGVSGAAQADVTASMYGCPSGAVCIYPDDDWNGGDPSHVFWSYGDHRIYNQYGEHRIYNNQTGNAWASLSRTSDGDTPINYVAPGSFTDTNLTPINAVSLYDVG
>NZ_CP042828.1|WP_147917256.1|2554164_2554560_-|hypothetical-protein
MSVKRIRNAATGLLATVALTMTAFVGLSGAAQAVPDRPPPPDTGCPSGAVCVYPGTGWNGGDPTYVFWSYDAHRIYNQYGDHRVFNNQTGGAHAVLSPDSDGSSWTVTIPAGTWTDENLTPINSVSLFPQR
>NZ_CP042828.1|WP_147919457.1|2553563_2553893_-|hypothetical-protein
MTAFVGLSGAAQAIPATPPAPDTGCPSGAVCIYPDESWNGGNPSHVFWSYGVHRIYNQYGDHRIFNNQTGGAAIDVCYGSDGTDCAFISAGFSQVFNLTPINSISLRTP
>NZ_CP042828.1|WP_147917255.1|2553049_2553379_-|LuxR-family-transcriptional-regulator
MQKPSLDAMARQVGRRAAEASSGRAAETVYGGHEKRLRQTVIAMTEGTELAEHESPGDATILVINGRLTLTAGDVSWEGRDGDFLAIPDERHSVQAVSDTAFLLTVAKR
>NZ_CP042828.1|WP_147917254.1|2552241_2552820_-|DUF805-domain-containing-protein
MQPAPPPPGGPGGYGSPGGYGSPGEYGSVAGQNPAPGYGSPYASYPAFSAPQIPTPAGLSLPGAVKEVLSKYATFQGRATRPEYWWWALAYLLVLGVPWLLAAVVVSVSNLRFEGSPLAGLLGFYTLIVILGLLVPTVAVTVRRLHDMGQSGWLYLITFVPTVGGIILLVLCALPSKPFANEYGLAPAPRLI
>NZ_CP042828.1|WP_147917263.1|2562779_2563184_+|RDD-family-protein
MSDVTQDRGSQASRGSRADEDAPQFPGYWGRRIAAICIDWALASAISAGFFAYDPMATLAVFGLMTFLLVGTAGTTIGHRILGVGMRTLAGGLPGPLRGLARTVGVLLVIPAVVTDPVGRSLHDRWSGTQVVRL
>NZ_CP042828.1|WP_147917264.1|2563272_2564442_+|FAD-dependent-oxidoreductase
MTGSRQRVVILGAGFGGLEVASMLSQALGDEAETTLVDRAESFVFGFSKLDFMFGHTEAEHVRLPYADAAHPGVRMVRAEVLGIDPVARTVTLSSGELAADILVIALGADLDPAATPGLVEAGHEFYTVPGAEAARDALQAFDGGRVVVAVTSTPFKCPPAPSETALLLHDFLTERGLRDKSTIDLVMPLPKPVPPSPAASEVILAAFEERGIGWHPGQLVRSVDPAARTVALGDGGEMAFDLLLAAPKHHAPQVVVDAGLTEDGWIPVDRRTLRTRFDGVFAVGDVTSVGTPKAGVFSEGQAAVVAEQIIEQVRGGSSAAEYGGQGVCLMEFGGGQVAKVDVTFAPDRAPYGGMVGPSVENAQEKQSFGAERARRWFGRDWVPVPARK
>NZ_CP042828.1|WP_147919458.1|2564476_2566285_-|amino-acid-transporter
MCLTGVDYFSTLGYQPAIAALAVGVLSPLATLVLVLVTVLGALPVYRRVARESPHGAGSIAMLERLLPHWRGKLLVLTLLGFAMTDFMITMTLSTADATAHLIHNPFMPAGLAGHEVGITLGLLGALGVVFLRGFREAIGLAVLVVGAYLALTAVLILICLIQVLGQPLVIGDWWTAVTTAHGNPVIAVALALLVFPKLALGLSGFETGVAVMPQVRGAARDTEDRPEGRIRGTTRLLSTAAVIMSAFLLTSNFATVLLIPGQEFQPGGQATGRALAYLAHEQVGEGFGTVYDLSTITILWFAGASAMAGLLNLVPRFLPRYGMAPPWARASRPLVLVLLAVAFAVTVAFDADVNAQGGAYATGVLVLISSAAVAVMLSARKQGQRRATVGFALITLVFVYTTVANIVERPDGIRTAGIFIGGLLVISFASRARRSFELHATGVRLAATAVEFRVALEQGPLYLIARDPREQGTLTYREKLAAVTVVHHLPADANVFFLEVVVEDSSEFETELNVHGTTRHGYRVLEVHGPAIPNSIASVLLYLRNITAEVPQMYFGWTEGNPLTNLLRFLVLGAGEIAPVTREILRRAEPDISQRPRVHVG
>NZ_CP042828.1|WP_147917265.1|2566624_2567341_-|DUF4191-family-protein
MAKKNTTDAGAAPKPKKKRWYHQIWEVFQMVRRAQPSITFVLLGIFLGVVAIGVAIGLLFDQVVYFALMSVPFGLLAAMFVLARRAETVAYRRIEGEPGAVSAALGTIKRGWNIEEEPVAIDPRHQDMVFRAVGRPGVVLIAEGPAHRVPKLLESERKRVARIVPNVPIVLLQCGRDEGQIPLPKIASKVRKQKPQLTKNETAEVSKRLRALKSHALPIPKGVDPRRARPDRKGMRGR
>NZ_CP042828.1|WP_147917266.1|2567395_2568049_-|hypothetical-protein
MKLAGTRSWRFAVEVSDVLHLALRVRDGAGLAVPASDDVPPPLTDPPAPIALDVDQQAAGIEWHAWWRELVELECRRQLLRPDQVTESWGKVTRRLRAELTAAADPPRFAALQERPALQAAARAVRPSPRRWVDQQLQAARGGQDVIDWAVVNTAVHAVAAQTGAGVNALNGCALVLLVRGSWWQQIRPGVVLASVDAAADPPAADALVHAALHSSL
>NZ_CP042828.1|WP_147917267.1|2568179_2569181_-|lipoyl-synthase
MAVAPEGRKMLRVEARNAAVPIEKKPSWIKTRATMGPEYTELRSLVQREGLNTVCQEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAAFDADEPRRVAASVQAMGLRYSTVTGVARDDLEDGGAWLYAETVRQIHQVNPGTGVELLIPDFNADPDQLAEVFSSRPEVLAHNLETVPRIFKRIRPGFRFERSLQVLTAAHEDGFVTKSNLILGMGETYEESVDALEQLHDAGCDLITITQYLRPSLRHHPVDRWVKPEEFVALSEEAERIGFLGVMAGPLVRSSYRAGRLWGQAMARRGQTIPEALAHLAEPVTARQEAASLLAR
>NZ_CP042828.1|WP_147917268.1|2569357_2570008_-|lipoyl(octanoyl)-transferase-LipB
MMIHRWGLGESLIDYHEAWDRQRDLHGAVVDGGADTTLLLEHASVYTAGRRTAKWDRPTDGTPVVDVDRGGRITWHGPGQLVAYPIVRLAEPVDVVAYVRALEQAVIDTCAHWGITAERVEGRSGAWVRGQDGAQDRKIAAIGVRVARGVTMHGVAINACPQLAAYSSIVPCGITDAGVTSISALTGGQISVTDCADAFEPHLQQALSPLLARVAA
>NZ_CP042828.1|WP_168211760.1|2570069_2570714_+|histidine-phosphatase-family-protein
MSDLQCAARFLVVRHAAAAYPDPDPVGGPDLGLTANGRAQARALAERLAGERVAAVFTSTMGRAEQTAQIVADGLGLAAEELPGVQEYAIGDLVGSEDQERVDAVFDSWVAGDLTAAYPGGESGADLVARFGLAIDDVADSYRGETVVVISHGGVMAVAIPRLAGRATPELLAARWLPHCAIARVDVDSDGWALQHWPGSPDPAAAEVVDNSAE
>NZ_CP042828.1|WP_147917270.1|2570779_2572210_+|hypothetical-protein
MSATVTVPGYTLTGVAGFGADGAVRRGTDADGRPVALRFLTEAPAGLRARVQAAARVHDPGVAGVLGLVELADGLAVVQDFIDGPTLSTLRAARRGLSVPECTQLAGGLLAALEGLHAAGIIHGDVSPANVIVTPTEEGAGRPVLVDLVGGAGPDRGTRGFRAPEVDTGAALGTAADVYSAAQLSLWAAESGAREEVAALLAPLLCREPGERPSARRARQLLDGGAQVAIALAPAEVLASATLREHAARELTTRARSRRLRPRRRHRAVGPRQWLLRAAAAAVLLTLVTGSAVWQGAVDLTPEAPPKAAPVSMAAGIASRVAQAAGEARAGHVQTSQGQAGDEETSTDTTAEIAAAVHDLLARRDAALTARDAVALADATVPGSPLAAADATVLTELTDADLQLRGYRTEVVQLRVLSRDPATAAVQAELSQPAHERLAADGSVSRVPEQPARCVRLELDRTGDDASWRATTATPC
>NZ_CP042828.1|WP_147917271.1|2572559_2573738_+|Cmx/CmrA-family-chloramphenicol-efflux-MFS-transporter
MPFALYMLALAVFVMGTSEFMLAGLLPAIAADLDVSVGTACLLTTAFAIGMVIGAPVMAAFARRWPPRLTLIVCLLVCAGSHVMGAMTPVFSLLLITRVLSAFAHAGFLAVALSTATTLVPANQKGRTLSILLSGTTMATVAGVPAGALLGTVLGWRTTFWAIAILCIPAAIGVARGISPKSGQSATSASSPRLRAELSQLATPRLILAMALGALINGGTFAAFTFLAPVVTETAGLAEGWVSVVLVMFGIGSFLGVTIAGRLSDQQPGLVLAVGGPLLLTGWIMVTFAAPDPVALILLVLVQGFLSFGVGSTLITRVLYAASGAPTMGGSYATAALNIGAAAGPVLGAVGLATGLGLLAPVWVASALTAIALVIMLLTGRALTQNPAEVRR

Crispr_ID: NZ_CP042828_10

• CRISPR_ID: NZ_CP042828_10
• CRISPR_location: 2590561-2590649
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NZ_CP042828_10

Consensus_repeat	Method
TAAGCCACGCGAGCTGCGCCGTC	CRISPRCasFinder

spacers of NZ_CP042828_10

>10.1|2590584|43|NZ_CP042828|CRISPRCasFinder
AGGGGAGTGCGCCCTGTGCGCCCCTACGCCTGGGGCGAGACCT

CRISPR arrays and Neighbor proteins around NZ_CP042828_10

CRISPR arrays

The CRISPR arrays of NZ_CP042828_10

>merge|NZ_CP042828|10|2590561-2590649|CRISPRCasFinder
TAAGCCACGCGAGCTGCGCCGTCAGGGGAGTGCGCCCTGTGCGCCCCTACGCCTGGGGCGAGACCTTATGCCACGCGAGCTGCGCCGTC

>NZ_CP042828|10|9|2590561-2590649|CRISPRCasFinder
TAAGCCACGCGAGCTGCGCCGTC	AGGGGAGTGCGCCCTGTGCGCCCCTACGCCTGGGGCGAGACCT
TATGCCACGCGAGCTGCGCCGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147917284.1|2587414_2588182_+|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl|CDD|224537
NZ_CP042828.1|WP_168211763.1|2584405_2585512_+|hypothetical-protein	unknown	unknown	gnl|CDD|376844
NZ_CP042828.1|WP_147917278.1|2580815_2581892_+|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl|CDD|235388
NZ_CP042828.1|WP_147917285.1|2588181_2589936_+|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl|CDD|238832
NZ_CP042828.1|WP_147917282.1|2585625_2585985_+|iron-sulfur-cluster-insertion-protein-ErpA	unknown	unknown	gnl|CDD|223393
NZ_CP042828.1|WP_147917289.1|2594300_2595080_-|c-type-cytochrome	unknown	unknown	gnl|CDD|129864
NZ_CP042828.1|WP_168211762.1|2583739_2584351_-|DJ-1/PfpI-family-protein	unknown	unknown	gnl|CDD|153233
NZ_CP042828.1|WP_147917290.1|2595130_2595781_-|heme-copper-oxidase-subunit-III	unknown	unknown	gnl|CDD|224758
NZ_CP042828.1|WP_147917292.1|2597753_2598035_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366431
NZ_CP042828.1|WP_147917286.1|2590856_2591468_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NZ_CP042828.1|WP_147917283.1|2586109_2587114_+|hypothetical-protein	unknown	unknown	gnl|CDD|223619
NZ_CP042828.1|WP_147917294.1|2600218_2602036_-|AMP-binding-protein	unknown	unknown	gnl|CDD|341233
NZ_CP042828.1|WP_168211761.1|2583061_2583646_-|DUF3043-domain-containing-protein	unknown	unknown	gnl|CDD|378611
NZ_CP042828.1|WP_147917291.1|2596480_2597545_+|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234682
NZ_CP042828.1|WP_147919459.1|2590001_2590400_+|cytochrome-c-oxidase-subunit-4	unknown	unknown	gnl|CDD|378833
NZ_CP042828.1|WP_147917287.1|2591599_2593279_-|ubiquinol-cytochrome-c-reductase-cytochrome-b-subunit	unknown	unknown	gnl|CDD|379304
NZ_CP042828.1|WP_147917279.1|2582027_2583041_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381300
NZ_CP042828.1|WP_147919460.1|2596066_2596477_+|response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP042828.1|WP_147917293.1|2598095_2599871_-|DEDD-exonuclease-domain-containing-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|236123
NZ_CP042828.1|WP_168211936.1|2593275_2594298_-|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl|CDD|239550

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP042828.1|WP_147917293.1|2598095_2599871_-|DEDD-exonuclease-domain-containing-protein	DEDDh	cd06127_DEDDh_CAS-I	4.2e-46	151.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147917284.1|2587414_2588182_+|cytochrome-c-oxidase-subunit-II	gnl|CDD|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	4.90911e-49
NZ_CP042828.1|WP_168211763.1|2584405_2585512_+|hypothetical-protein	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	8.56984e-37
NZ_CP042828.1|WP_147917278.1|2580815_2581892_+|quinone-dependent-dihydroorotate-dehydrogenase	gnl|CDD|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	1.58552e-149
NZ_CP042828.1|WP_147917285.1|2588181_2589936_+|cytochrome-c-oxidase-subunit-I	gnl|CDD|238832	cd01662, Ubiquinol_Oxidase_I, Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits in ubiquinol oxidase varies from two to five. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons from ubiquinol to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from ubiquinol on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. It is generally believed that the channels contain water molecules that act as 'proton wires' to transfer the protons. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are believed to be transferred directly from ubiquinol (the electron donor) to the low-spin heme, and directly from the low-spin heme to the binuclear center.	0
NZ_CP042828.1|WP_147917282.1|2585625_2585985_+|iron-sulfur-cluster-insertion-protein-ErpA	gnl|CDD|223393	COG0316, sufA, Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones].	1.96057e-45
NZ_CP042828.1|WP_147917289.1|2594300_2595080_-|c-type-cytochrome	gnl|CDD|129864	TIGR00782, di-heme_cytochrome_cp, cytochrome c oxidase, cbb3-type, subunit III. This model describes a di-heme subunit of approximately 26 kDa of the cbb3 type copper and heme-containing cytochrome oxidase. [Energy metabolism, Electron transport].	7.08721e-14
NZ_CP042828.1|WP_168211762.1|2583739_2584351_-|DJ-1/PfpI-family-protein	gnl|CDD|153233	cd03139, GATase1_PfpI_2, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	3.76172e-30
NZ_CP042828.1|WP_147917290.1|2595130_2595781_-|heme-copper-oxidase-subunit-III	gnl|CDD|224758	COG1845, CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 [Energy production and conversion].	1.02782e-45
NZ_CP042828.1|WP_147917292.1|2597753_2598035_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|366431	pfam01037, AsnC_trans_reg, Lrp/AsnC ligand binding domain. The l-leucine-responsive regulatory protein (Lrp/AsnC) family is a family of similar bacterial transcription regulatory proteins. The family is named after two E. coli proteins involved in regulating amino acid metabolism. This entry corresponds to the usually C-terminal regulatory ligand binding domain. Structurally this domain has a dimeric alpha/beta barrel fold.	1.95224e-14
NZ_CP042828.1|WP_147917286.1|2590856_2591468_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	1.83154e-91
NZ_CP042828.1|WP_147917283.1|2586109_2587114_+|hypothetical-protein	gnl|CDD|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	1.30026e-20
NZ_CP042828.1|WP_147917294.1|2600218_2602036_-|AMP-binding-protein	gnl|CDD|341233	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases. This family includes long-chain fatty acid (C12-C20) CoA synthetases and Bubblegum-like very long-chain (>C20) fatty acid CoA synthetases. FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Eukaryotes generally have multiple isoforms of LC-FACS genes with multiple splice variants. For example, nine genes are found in Arabidopsis and six genes are expressed in mammalian cells. Drosophila melanogaster mutant bubblegum (BGM) have elevated levels of very-long-chain fatty acids (VLCFA) caused by a defective gene later named bubblegum. The human homolog (hsBG) of bubblegum has been characterized as a very long chain fatty acid CoA synthetase that functions specifically in the brain; hsBG may play a central role in brain VLCFA metabolism and myelinogenesis. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	0
NZ_CP042828.1|WP_168211761.1|2583061_2583646_-|DUF3043-domain-containing-protein	gnl|CDD|378611	pfam11241, DUF3043, Protein of unknown function (DUF3043). Some members in this family of proteins with unknown function are annotated as membrane proteins. This cannot be confirmed.	1.08897e-59
NZ_CP042828.1|WP_147917291.1|2596480_2597545_+|anthranilate-phosphoribosyltransferase	gnl|CDD|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	3.49142e-150
NZ_CP042828.1|WP_147919459.1|2590001_2590400_+|cytochrome-c-oxidase-subunit-4	gnl|CDD|378833	pfam12270, Cyt_c_ox_IV, Cytochrome c oxidase subunit IV. This family of proteins is found in bacteria. Proteins in this family are approximately 140 amino acids in length. This family is the fourth subunit of the cytochrome c oxidase complex. This subunit does not have a catalytic capacity but instead, is required for assembly and/or stability of the complex.	1.9428e-49
NZ_CP042828.1|WP_147917287.1|2591599_2593279_-|ubiquinol-cytochrome-c-reductase-cytochrome-b-subunit	gnl|CDD|379304	pfam13631, Cytochrom_B_N_2, Cytochrome b(N-terminal)/b6/petB.	8.59391e-65
NZ_CP042828.1|WP_147917279.1|2582027_2583041_-|aldo/keto-reductase	gnl|CDD|381300	cd19074, Aldo_ket_red_shaker-like, Shaker potassium channel beta subunit family and similar proteins. This family includes voltage-gated potassium channel subunits, beta-1 (KCAB1B), beta-2 (KCAB2B) and beta-3 (KCAB3B). KCAB1B and KCAB2B are cytoplasmic potassium channel subunits that modulate the characteristics of the channel-forming alpha-subunits. KCAB3B is an accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. The family also includes Drosophila melanogaster Hk protein, a founding member of aldo-keto reductase family 6 member B1 (AKR6B1), as well as voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa, founding members of AKR6C1and AKR6C2, respectively. Hk protein, also called hyperkinetic, is a beta subunit of Shaker (Sh) K+ channels and shows high sequence homology to aldoketoreductase. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	1.13654e-159
NZ_CP042828.1|WP_147919460.1|2596066_2596477_+|response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.03543e-06
NZ_CP042828.1|WP_147917293.1|2598095_2599871_-|DEDD-exonuclease-domain-containing-protein	gnl|CDD|236123	PRK07883, PRK07883, DEDD exonuclease domain-containing protein.	0
NZ_CP042828.1|WP_168211936.1|2593275_2594298_-|Rieske-2Fe-2S-domain-containing-protein	gnl|CDD|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	8.30848e-24

Protein sequences

>NZ_CP042828.1|WP_147919459.1|2590001_2590400_+|cytochrome-c-oxidase-subunit-4
MRPEAIFFIALVAFFLPVFLIYGFWSSWEPVGSTVLLLCVGLWGLTGFYLMLVSRRIDPRPEDNPVAEVAEGAGEYGTFSPWSWWPLVIGLGVTFAFLGAAAGWWLTGIGFVIGLGGLVGHVLEYSRGPHAH
>NZ_CP042828.1|WP_147917285.1|2588181_2589936_+|cytochrome-c-oxidase-subunit-I
MAVQDDAAPEITETTAEQSTIPGLRDERRTLGRTVVSWITTTDHKTIGYLYLITSFLFFCVGGVLALLIRAELFEPGVQIVNSSEQFNQLFTMHGTIMLLLFATPLFVGFGNVLVPLQIGAPDVAFPRLNMFAYWLFLFGGLMAVAGFLTPRGAASFGWTGYAPLADATYSAGLGGDLWVMGLAMTGFGTIFASVNFITTILCMRMPGMTMFRMPIFTWNILLTSVLALMAFPVLASALFGLASDRILGSQIFAASNGGVMLWQHLFWFFGHPEVYIIALPFFGIITEILPVFSRKPVFGYLGLVIATISIAGLSTTVWAHHMYSTGPVLLPFFSVMTMLIAVPTGVKFFNWVGTMWRGKLTFQSPMLWSIGFLVTFLFGGLTGVILASPPLDFHVTDTYFVVAHFHYVVFGTVVFAMFAGFYFWWPKFTGKMLDDRLGKVHFWMLFFGFHGTFLIQHWLGVMGMQRRIPDYLPEPDFVWMNQLSTVSAVLLAVSTLPFLWNVYKTWRHAPKVTVDDPWGHANSLEWATSCPPPRHNFVTLPRVRSERPAFDLHHPEVAALDHAEPEPALMGGEPSSSSERKDR
>NZ_CP042828.1|WP_147917284.1|2587414_2588182_+|cytochrome-c-oxidase-subunit-II
MPSDPGITEHTEGILNLWTGSWIAALAIGVLMWALIIWCVIVYRKRKDDNRLPVQLRYHLPLELLYTFVPIVMVGVLFYYTATLQEEITNPDVEPDVHVTVYGRQWSWDFVYEDEDVWDAGTPAELDGTMAPAGDLPTLYLPVDQTVEIQLRSRDVAHSFWVPAFLYKEDLLPGVENEFIITPGEEGTYLGKCAELCGEYHGNMLFNVEVVSAQEYEQRMTELRDAGQTGELGSELDRQNAADVPDPTTVEGADD
>NZ_CP042828.1|WP_147917283.1|2586109_2587114_+|hypothetical-protein
MIRTRLLPGLLATLTCAALVAGCGSEDPGPDPTGPAGSESPSAEASADGAGEAEGAGDGSGEAGTALPEATGEFGDAPEFTFPESAPPADLQVEVLSEGDGPMVQPGAAVLAHYAGIVWGGDTTFDDSYSRGAASMFSLSGVVQGWTEGIPEHPVGSRLLISIPPDLGYGPSGGNPQAGIGAEDTIVFVVDVVETYNPDMTGQEDATVQTEAAELPVEVAGELGEPATVTIPEDAEEPAELEVITLAEGSGDPVAAGDQVALAYAVDSWDGSMQGSSWPSDSAEGTGPFAAAAGQGSIVDAVVDIPVGSRVLLLVPGNEQQPATAYVVDVLGAA
>NZ_CP042828.1|WP_147917282.1|2585625_2585985_+|iron-sulfur-cluster-insertion-protein-ErpA
MSQTTTPTEELSHEVALTDLAAGKVKALLNQEGRDDLRLRVAVQPGGCSGLIYQLYFDERMLDGDAVRDYEGVEVIVDKMSVPYLAGATIDFADTIEKQGFTIDNPNAGGSCACGDSFH
>NZ_CP042828.1|WP_168211763.1|2584405_2585512_+|hypothetical-protein
MHVLIAPESIAPMLSAVDTAAALAAPWREAGHQVREMPLGTGATGLIDAVSAAKGGTTHPVAVRGPHAVAEMLLVERTAFLEAGPVLAGAPQPDAHGLLGSTAPVAELLLAAQQAGATRMVLGLGATAMHDGGAGVLSRLAEAFGCSAEPSADTLTALRNGVAGLQIDVAAGTDLPLLGLHGAGAALARYPGLDATIAQRAENRVGEQVSAWERADAGTVRHSLLTGDRAPRPGRAPHSGAGGGAGFALALLGARLLPGTELVAAEVGLAEAVAEADLVITAAPALDGDAMHDGVPAVVGQSAMEVGLPVVAIGWEVHTSRRDGARVGISATYPVIEARMPGSQAPPSPDPLTALRARGVRIVKTWAQ
>NZ_CP042828.1|WP_168211762.1|2583739_2584351_-|DJ-1/PfpI-family-protein
MGTHSPVRVGIVLFDGADELGIVGPHAVLSTWARSASTHPDVLLISRDGEPVRCDAGLDLVPTAAPAEFEHLHVLIHPGGPGARRLTRDPQYLGWLRRVRHRTPMLAALGAGCLPLAAAGLMAGRAVTVHPDLAGELLSVEPGALLDTAASTVDDGDLVTCAAGGHAVDLALHLVERLDSAQACVRVRRELHFEPTAEPPTHW
>NZ_CP042828.1|WP_168211761.1|2583061_2583646_-|DUF3043-domain-containing-protein
MFGRKKETAEPTAVEEPEPIGKGRPTPKRKVSEARNKRPLVPSDRAAARRAQREKMASARAKMDEAMVTGNDQYLPAQHRGRARRFLRDYVDARWSIGEAFMPLAVLIVVILLLASFLPIPVVVATGAFYGLYIVMFIALIDAVLLGYRVRRKAVEKFGDGARKGAVMYVAMRVFQIRRTRLPKPQVKRGEFPV
>NZ_CP042828.1|WP_147917279.1|2582027_2583041_-|aldo/keto-reductase
MRFRHLGHSGLKISEITYGNWLTHGSQVENETAAQCVQAALDAGITTFDTADTYANTRAEEVLGAALADQRRESLEIFTKVYFPTGPKGPNDTGLSRKHIMESINGSLRRLGTDYVDLYQAHRFDHATPLEETMQAFADVVRSGKALYIGVSEWTAEQLRAGHALARDLGIQLISSQPQYSMVWRVIEEKVVPASEDLGISQIVWSPVAQGILTGKYLPGQAAPEGTRAADTKGGAKMISGLLGREELLRRVQDLRPVAEELNLTMAQLAVAWVLQNRNVAAALIGASRPEQVAENVAASGVEIPAELMTRIDEILGDSVVRDPQHTYDISPKERLV
>NZ_CP042828.1|WP_147917278.1|2580815_2581892_+|quinone-dependent-dihydroorotate-dehydrogenase
MGVRAGGGKRIRLASVPRIYDTLFRLGFTRLDAEQAHHLAGALIRVAGATPPLRGAVRASFGRPAGAAGEPMTLFGREVYGPLGVAAGFDKNATMAAGLGALGFAFVEIGTVTARPQPGNEKPRLHRVIERSALVNRMGFNNAGAHAAARRLARLRRTPHGRRLVLGANIGKTKLTPASDAVADYVTSARAVAPHVDYLVVNVSSPNTPGLRDLQQTEALRPILAAVRDAATAAAAREVPVLVKIAPDLADADVDGVAHLASELGLAGVVAVNTTIAHEYGAGGLSGAPLVDRGVEVVRRVRRVLGDDAVVIGVGGISTENDARRYLDAGATAVQAYTAFIYRGPAWPGRLNRALARR
>NZ_CP042828.1|WP_147917286.1|2590856_2591468_-|superoxide-dismutase
MAQYTLPDLPYDYAALEPHISGKIMQLHHDKHHNTYVQGANAALEKLEAARDSGDLAAVNLLEKNLAFNLGGHINHTIFWNNLSPDGGGQPDGELAAAVKEFFGSFEAFQAHFTANATGIQGSGWSVLGWDSLGQRLAIFQLFDQQANVPVSITPLLMLDMWEHAFYLDYLNVKADYVKAFWNIANWQDVAARFEKARAHSTV
>NZ_CP042828.1|WP_147917287.1|2591599_2593279_-|ubiquinol-cytochrome-c-reductase-cytochrome-b-subunit
MSAGTDAPAQKPDPRLAATADFLDTRVGISKIVKEFARKIFPDHWSFLLGEIALYSFIVLLISGTFLTMFFVPSMAHTTYPEDALPVTMQGLGMSEAFASTLDISFHVRGGLLMRQIHHWAALLFVGSMVIHMLRNFFTGAFRRPRELNWLVGFLLLIMGLLAGFSGYSLPDDVLSGNGLRIADGVLRAIPIIGSYGSYGLFGGEFPGTDIIPRLFTVHILLVPALILALIAVHLFLVVWHKHTQYPGPGRTEKNVVGFPLFPVYTAKAGGFFFIVFGVIALMGATMSINSVWAYGPYDPSIVGAGAQPDWYMLFLEGSLRLMPGWEFVIGGYTLSLNILVPGVVIPGLLFTFLALYPFIEGAVTKDRGEHHLLDRPRNAATRTALGAGFLSIWFVLIGAGSNDLISTHFNVSLNLITWIFRILFFVLPVVTFMITRRICYGLQRKDRELALHGHETGRVVRFASGEFIEVHKPLDSYERWVLVSHHSPAPLEIEPAEDANGVARPGFEKDKRRRRLSQFFYEDRIEPVTPAELAAAQSHGEHDQLEGSETEQLEARTH
>NZ_CP042828.1|WP_168211936.1|2593275_2594298_-|Rieske-2Fe-2S-domain-containing-protein
MEQHKEPDPAHPERFENPGLPPHRPRLGDGDPKANKRSERQVVVLFVISILATIAGIWGYFAFPVDGTDAGNVRMSTLVIGLGLGLGALGIGVAAVHWAKSLMNDHEKVEERHPQRGDDAARAEAVDIMTEGVADSSIARRPMLKGALGTAVAIAPLAFLVPLVGNLGADWNVSKFRYTAWASAPGGGRRYLATDPTDRRIKASDVTRGSMVHVQPWRLEDEPHFLEEKTKAIVILMRLDPGLLKEPEEKKDWSYDGIVAYSKVCTHVGCPVALYEQQTHHVLCPCHQSTFDITDQAKVIFGPAKRPLPQLPIAVDEDGYLYAQSDFTEPVGPSYWEQQK
>NZ_CP042828.1|WP_147917289.1|2594300_2595080_-|c-type-cytochrome
MKALAAGRRHRLAPVVLMTLALLFTGVLYAALAPSPAQAETASAGDVEAGERLFIANCSTCHGLNAEGAGTAPSLIGVGAASVHFQITTGRMPMDANQPQAEAKPPQLDEEQALQVAAYISSLGPGPGIPSEQQVDPALGDPTLGGQLFRTNCAMCHNAVGAGGALTNGKHAPALYDSTPTEIFEAMLTGPQSMPVFNNANLTEDEKRDVIAYLMEQREPAPGGFSLGSLGPVSEGLWAFAVGMGLLIGFAVWIGARSS
>NZ_CP042828.1|WP_147917290.1|2595130_2595781_-|heme-copper-oxidase-subunit-III
MSSATSAPSTPHLAVNRPNLTQVGTIVWLSSELMFFAGLFAMYFTHQAVAGPEVWSAGYDHLNVTFSAINTLVLVLSSVTCQLGVWAAEEFRKVRSGPIWQVTRWGMQEWFILTFLMGSFFVAGQVFEYAELAHEGLTIANSSYGSVFFIPTGFHGLHVLGGLIAFLFVLLRSFSAHRFGERDATFALVVSYYWHFVDAVWIVLFGTIYLLPLLQL
>NZ_CP042828.1|WP_147919460.1|2596066_2596477_+|response-regulator
MAPKGEQTEQEPVSVLLYSDDVTTREQVLTGVGRRASFDTPKIRWHEAATPAAVVDYVTNREYDLVVLDAEAAKLGGMGLCRTLKSEVYQCPPVLLLIARAQDAWLAAWSEADAVVSMPLDPIELQETMADMIRRR
>NZ_CP042828.1|WP_147917291.1|2596480_2597545_+|anthranilate-phosphoribosyltransferase
MATGEVTWPDLITRLIGGGDLAPDETSWAMDQVMSGNSHPIALGGFLVALRAKGETVPEVRGLADAMVAHAVPIDVDRDAVDIVGTGGDRHRSVNLSTMAALVVAGTGTTVVKHGNRASSSASGSADVLEALGVRLDLPPEESAQVVQSAGITFLFANAYHPSFRHAAATRRELGVATAFNILGPLTNPARPRASAIGVADPRMAPLVAGVFADRANSTLVFRSEDGLDEMATTAPVRIWEVTEAGGPEIAEHLLDPAEVFGLPRATLEDLRGADPAHNAQVTRDVLAGAEGAIRDTVLLNAAAALVAHARLDGTTTGPLTDRLLAGLEHARRSIDDGAAAATLQAWVAASQAA
>NZ_CP042828.1|WP_147917292.1|2597753_2598035_-|Lrp/AsnC-family-transcriptional-regulator
MITAIVLIDTEADSIPEVAGQVAELPGVTEAFSVTGDVDLIAVVRVSQHEDLAGVIADRISKIDGVVRTQTYIAFQTYSRHDLDAAFALGLDD
>NZ_CP042828.1|WP_147917293.1|2598095_2599871_-|DEDD-exonuclease-domain-containing-protein
MRASLFTAARPGGRIDRPDAGAGAIGLPQQLGFDEIGTPLFDATFVVVDLETTGGSANESAITEIGAVKVRGGETVGEFQTLVNPGVGIPPTITLLTGITNAMVLPAPRISTVLPAFLEFVGDAVLVAHNARFDVGFLKANAARLDLPWPRPMVVDTLALARRVVTRDEAPNHKLGTLAALFRTEVTPDHRALTDARATVDVLHGLFARMSSLGLTHVEDLATASDPVPPARRRKATLADDLPTCPGVYLFLGPRQEVLYVGTATNLRRRVRSYFTAAEKRARIGEMVDLATAVKPIPCATALEAAVRELRAIAEHDPRYNRRSKAPGRRPWVRLTAEAYPRLSVARSAPQVDGGAAIGPFPSRASAALAVEAMVAATGLRTCTGSLPRIPKPQANACILLELGRCSAPCVHPDTDYGDRVLRAEQVLGGNADAVVQTMTATISRLSAQERFEEAAVRRDQLLAYLRIAARAERLDPLRRARQILAARRADGGGWEILLVRYGRFAGTAVSPPGRSPMPVVDSLRETGAQVQPGQTRAGAASDEETALLADWLERPGTRLIETDLDGADGPGWSLPVRGAGRHLDRLSPRP
>NZ_CP042828.1|WP_147917294.1|2600218_2602036_-|AMP-binding-protein
MSQTETPLLVETPDELSIPDLLIDWAAKEPQRVLMEIPDGDAWSPITAAQLHERVLGLARGLIASGVGPGDRVAIMSRTRAEWTIADLAIWYAGAVTVPVYETSSVEQTAWILEDSGTDRVFVENAGHAATVSEAAQQVGREIPVWVIDDGALDELTSSGADVTEEQVRERYDALRLSDLATVIYTSGTTGRPKGVELTHSNFVELTRNAQAALGSQILHDQARTLLFMPLAHVFARFVSILTLCCGVPIGHVSDTTTLLPNIATFKPTFILSVPRVFEKVYNSSEQKAAAGGKVKIFRWAAKVSGDYSRSLDDGGPGLGLRLQYALADKLVLHKIREALGGQAEYAISGGAPLGERLGHFFRGVGVRVLEGYGLTETTAPVTVNVPERSKIGTVGPPLPGVSIKIAEDTEILTRGIANFRGYHDNPEADAESITDGWFHTGDLGELDADGYLKITGRKKELIVTAAGKNVQPSVLEDRIRAYPLVSQCVVVGDQRPFVAALITLDTEMLPTWLSNQGLPEMSVTEAAAHPQVQEGLQGAIDRANRAVSRAESIRKYEVLDEDFTLDDYLTPKLSVKRNLVLRDFADRIDTLYEKAAAERASEQH

Crispr_ID: NZ_CP042828_11

• CRISPR_ID: NZ_CP042828_11
• CRISPR_location: 3290428-3290524
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP042828_11

Consensus_repeat	Method
TAGCGACCCACCCGCCGACTACGGCCCACCGCC	CRISPRCasFinder

spacers of NZ_CP042828_11

>11.1|3290461|31|NZ_CP042828|CRISPRCasFinder
CTTCTGAACCCCCCGGGGGACGCCCGAGGAG

CRISPR arrays and Neighbor proteins around NZ_CP042828_11

CRISPR arrays

The CRISPR arrays of NZ_CP042828_11

>merge|NZ_CP042828|11|3290428-3290524|CRISPRCasFinder
TAGCGACCCACCCGCCGACTACGGCCCACCGCCCTTCTGAACCCCCCGGGGGACGCCCGAGGAGTAGCGACCCACCCGCCGAGTACGGCCCACCGCC

>NZ_CP042828|11|10|3290428-3290524|CRISPRCasFinder
TAGCGACCCACCCGCCGACTACGGCCCACCGCC	CTTCTGAACCCCCCGGGGGACGCCCGAGGAG
TAGCGACCCACCCGCCGAGTACGGCCCACCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147917849.1|3283064_3283331_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917852.1|3284849_3287321_-|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NZ_CP042828.1|WP_147917856.1|3290557_3291172_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NZ_CP042828.1|WP_147917860.1|3293983_3295192_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|224029
NZ_CP042828.1|WP_147917861.1|3295263_3296325_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP042828.1|WP_147917853.1|3287783_3288083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917854.1|3288079_3288514_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147919527.1|3278781_3279927_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP042828.1|WP_147917857.1|3291227_3291578_-|helix-turn-helix-domain-containing-protein	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|223713
NZ_CP042828.1|WP_147917850.1|3283327_3284350_-|hypothetical-protein	unknown	unknown	gnl|CDD|379142
NZ_CP042828.1|WP_147917851.1|3284429_3284840_-|pilus-assembly-protein-CpaE	unknown	unknown	unknown
NZ_CP042828.1|WP_147917848.1|3282214_3282973_-|metallophosphoesterase-family-protein	unknown	unknown	gnl|CDD|378975
NZ_CP042828.1|WP_147917859.1|3292859_3293984_-|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NZ_CP042828.1|WP_168211792.1|3298533_3299865_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP042828.1|WP_168211791.1|3297324_3298362_-|adenosine-deaminase	unknown	unknown	gnl|CDD|238645
NZ_CP042828.1|WP_147917865.1|3299848_3300133_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917847.1|3281437_3281803_-|DUF4345-family-protein	unknown	unknown	gnl|CDD|372978
NZ_CP042828.1|WP_147917858.1|3291657_3292830_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP042828.1|WP_147917846.1|3280163_3281132_-|type-IV-toxin-antitoxin-system-AbiEi-family-antitoxin-domain-containing-protein	unknown	unknown	gnl|CDD|379128
NZ_CP042828.1|WP_168211790.1|3296315_3297302_-|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP042828.1|WP_147917857.1|3291227_3291578_-|helix-turn-helix-domain-containing-protein	csa3	COG0640_csa3_CAS-I-A	8.1e-13	43.5	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147917852.1|3284849_3287321_-|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP042828.1|WP_147917856.1|3290557_3291172_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.56222e-16
NZ_CP042828.1|WP_147917860.1|3293983_3295192_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	8.44777e-149
NZ_CP042828.1|WP_147917861.1|3295263_3296325_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.40991e-06
NZ_CP042828.1|WP_147917857.1|3291227_3291578_-|helix-turn-helix-domain-containing-protein	gnl|CDD|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	6.01904e-10
NZ_CP042828.1|WP_147919527.1|3278781_3279927_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	4.99768e-53
NZ_CP042828.1|WP_147917850.1|3283327_3284350_-|hypothetical-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	0.00158928
NZ_CP042828.1|WP_147917858.1|3291657_3292830_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	5.15664e-59
NZ_CP042828.1|WP_147917848.1|3282214_3282973_-|metallophosphoesterase-family-protein	gnl|CDD|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	1.41179e-14
NZ_CP042828.1|WP_147917859.1|3292859_3293984_-|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP042828.1|WP_168211792.1|3298533_3299865_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	7.75084e-127
NZ_CP042828.1|WP_168211791.1|3297324_3298362_-|adenosine-deaminase	gnl|CDD|238645	cd01320, ADA, Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.	1.33444e-79
NZ_CP042828.1|WP_147917847.1|3281437_3281803_-|DUF4345-family-protein	gnl|CDD|372978	pfam14248, DUF4345, Domain of unknown function (DUF4345). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 125 and 141 amino acids in length. There is a single completely conserved residue E that may be functionally important.	3.372e-07
NZ_CP042828.1|WP_147917846.1|3280163_3281132_-|type-IV-toxin-antitoxin-system-AbiEi-family-antitoxin-domain-containing-protein	gnl|CDD|379128	pfam13338, AbiEi_4, Transcriptional regulator, AbiEi antitoxin. AbiEi_4 is the cognate antitoxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	0.00113528
NZ_CP042828.1|WP_168211790.1|3296315_3297302_-|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.90162e-61

Protein sequences

>NZ_CP042828.1|WP_147917854.1|3288079_3288514_+|hypothetical-protein
MSGIYSSASSDPFGGRYADRGLIFGRDSAENRPDRPRYVSGVAMAIGMVLVWASFFGPLLTAGLVGLSWWGTTEGWVMPDSAPSAAVSGAALLGVWLVSSITALVARRDLRRLRVTGGLVKLAVSALVLGAGLWWAVSVNQIPL
>NZ_CP042828.1|WP_147917853.1|3287783_3288083_+|hypothetical-protein
MALAVLLVLGSLAYLVWHSVTWLEPLVESLDGCPVERGTACFTSEPFRRWLYAPILAAVLAWGFASGAATEGRQGRARGYLHLLAGIAALVIAGLVSNL
>NZ_CP042828.1|WP_147917852.1|3284849_3287321_-|NAD-dependent-DNA-ligase-LigA
MADVNEQAPEGQDPTTDESAEELRARWQDIADRVRSAREAYYSEDAQLMSDAAFDELLRDLQALETTHPFLQRPDSPTQEVGGSASPLFTPVQHAERLLSLDNVFTVEELGDWLTKTQEAAGRQVRWLCELKIDGLAIALRYENGRLVSAATRGDGRIGEDVTANAIRVGAIPRRLSGTGHPELVEVRGEVFIPTAAFADLNELQAELQGRAVAASRERWEKRPAATRAAFDDERETTSAARRFPAFANPRNAASGGLRQQLEKKEGLEREAGDARVKSLALYVHGIGAWSRPPVASQSEVYDLLAGWGLPTSPYSSVAGSVEEVLAFVERYGENRHSVEHEIDGVVVKVDELALHDELGATSRAPRWAIAYKYPPEEVHTKLLDVAVGVGRTGRATPYAVMEPVQVAGTVVRQATLHNQDVVRAKGVLIGDTVVLRKAGDVIPEVLGPVVELRDGSEREFTMPSHCPECGTELRAMKEGDIDLRCPNARSCPAQVRGRVEHIGSRGALDIEALGEVTAAALTQPQTPATPPLVTEAGLFGLTIEELVPIAVVVRDAETGEPKTDEETGEVTVRRPFQKTRLDYPPEAEGMSAAERRKAGYRKNHTVTEPSAQALTLVAELEAAKTKDFWRQLVALNIRHVGPVAARALASWFGSLTAIEAAEEEALAQVDGVGPTIAGALEEWLAVDWHTEILERWRAAGVQFAIPDHPGPGAASDGGALAGLSIVVTGSMENYSRDGAKEAIISRGGKAAGSVSKKTDFVVVGPGAGSKETKARDLGRPILDEAGFQLLLDGGPEAVAHLVGEQPDADDEATAESESPGDA
>NZ_CP042828.1|WP_147917851.1|3284429_3284840_-|pilus-assembly-protein-CpaE
MISDPLAHELRNAGVRWDPAPGDRFRIQAEALGEDVFILSHMVIEPRHYETGTVLHFNGTTEWALDSVAQEDALWLPREDQLRELLGGTFLRMERSGGEFAVQTSGPDGQVQSFAADDVEDAYAHALLELVHRAVA
>NZ_CP042828.1|WP_147917850.1|3283327_3284350_-|hypothetical-protein
MHIDLARERKAHWLTFAREALITPESTAAPVAVAFGLAVRDGGEYGLAVRYRDEAECSDLLGQIAEADSDADIRHVGQIVAQTLPPDRPSPPQPPGPPGGPGQPGQPEPPGGQLGDLRSRVRPLRPGLSIANANVTAGTLGAFVADSDGTLYALSNWHVLAGSTTAVAGDPILQPGPADGGTSADQVGTLDRVVALDPSAPNIVDAALALLTEQQEDAGYPIGAVTSTAPADGGQQVGKIGRTTGITAGRVSAVELDGMRVNYGEDLGDLTFDNQIEVTGDQGAFSAGGDSGSLVYREDGVAVGLLFAGSETGGPTGTGLTFLNPIDQVLRGLEVGLLQP
>NZ_CP042828.1|WP_147917849.1|3283064_3283331_-|hypothetical-protein
MTARGGQCSRDQARAAKAQATERLAELPGVVGIGLEKQPDGGWCVRVNVTSAEVAEAVAERLPGETQAAPVRVRVTGTVHASSDPPEG
>NZ_CP042828.1|WP_147917848.1|3282214_3282973_-|metallophosphoesterase-family-protein
MTQPQRIALISDIHGNLTALTAVLADIDARGIETIYNLGDVAGKGPRGSAAIQLSRQRCAVTIGGNWDDFLPDEQPTDSEPLRWWREELSPADRQWLRDLPLVHDLVLSGRRIRLFHASAQSVYTRVWSQHTPEEFDGMFAATELTGPGPVPDVVAYGDIHETFLKVAGSRTLLNVGSVGNALDEPAAAYAILEGTPGQEQVALGIQFVRVPYDVEAEIAVATSLDMPTTATYAIELRTAVYRGLHAALGLG
>NZ_CP042828.1|WP_147917847.1|3281437_3281803_-|DUF4345-family-protein
MRTGLLRGLLWSISGVATLTGLLVAIRGNRAIPGATDRTDASTSSVLRFYAVIWAAQAIVVGRAAARKDLDHEEIAGIGWLMAAGGAARALAWRQSGPPHPLFRALTVQELAMPLIVRLLR
>NZ_CP042828.1|WP_147917846.1|3280163_3281132_-|type-IV-toxin-antitoxin-system-AbiEi-family-antitoxin-domain-containing-protein
MPALPFDTHGLVTSADATRAGMRAVLQGMVASGKLERLWPGVYRRPLSIGTPAERAAEAYRARVLAAARRLRRPVFASYSAAALLGLPIIGTWPDEIFILSGRATGSRQGRLVRLATRCDPPLMENGDLRITSVAYTLIQLARQARLGAAVVAADAALRDLPYGPKAAPLTTLTELMAMHQRLLPYPRSNRVQAMLDRATHLSASALESVSRLAIEELGLATPQLQVRLHLDAPHGDVYLDFGWEQDIGGESDGDSKYLAPDNTVATAARLLAEKEREDAMRAKLRGLARWGWRDAWQGSPLRRKLLQVGVPQVRSSVARFW
>NZ_CP042828.1|WP_147919527.1|3278781_3279927_+|ROK-family-protein
MLQILRDGAPRARADLVAVTGHARTTIGSRIDALLRTGLVRTEAASSTGGRPPSVYVFDPGARVVLAVDLGAVHLSVAVLDLAGTVLAEERTVCDIAEGPDPVLAHVNELGQQLLDRLGRPATDLAGVGIGVPGPVQQTTGRPITPPIMPHWDGVDIKGILGRQFGVPVLVDNDVDLMALGEHGAVYPEVSHLLFVKVATGIGAGIIANRTLVRGTDGAAGDLGHVAVPGGRAELCHCGNSGCLEAVASGGALVRALRAAGEEVATSADVVDLVRRGDQRATALLRDAGRDLGAVLAGCVNLLNPSAIVIGGVLAQAGEHLLAGAREVVYRRSLPLATKQLRIVTASTAGRAGLLGAGRVVADHVLAPAAVDALAAAQTPV
>NZ_CP042828.1|WP_147917856.1|3290557_3291172_+|methyltransferase-domain-containing-protein
MVEKSLWARKVEQNPDHSHWYVQRFRSMAAAGADLHGEARFIDAMAERGSRILDAGCGPGRVGGELAQRGHQVMGVDVDPVLIEAAETDHPGSTWVVQDLAELDLHGSAEPFDVIVAAGNVMTFLAPSTRYEVLRRLGSHLAPEGRMVLGFGAGRGYPFEEFFADAEQAQLTIELRLATWDLRPWTPESDFLVAVLSVPDPLSL
>NZ_CP042828.1|WP_147917857.1|3291227_3291578_-|helix-turn-helix-domain-containing-protein
MAKDAQHPDLDEVALTTVLAALSDPLRLGLVRLLSDGVERQWGELDAPVAKSTLSHHLKVLRSSGVTRTRDEGTRCYVHLRADDLEQRFPGLLQSLLATADDGATTVTIKEPRQSA
>NZ_CP042828.1|WP_147917858.1|3291657_3292830_+|MFS-transporter
MTSRRIPGWLAGLFVATLALGTDEFVIAGLLPELATDLQISTGAAGQLITVFALTFAIGAPVMAVALDPLPRRHVILAGLAVFILANGAAAIAPTFGILLALRAVAGLAAAVVSATAFAIAAQGAPPDRQGRYLAVVTAGLTVALFTGVPVGTWVGALFGWRSTFVLIAIVALGAMCVLAVTTPRLQGSPAMGLGPRLSPLRDPRVLRLVLAVFLSGAGGLMFYSYLSVLLDHHQGDTSALPGVLLLVGVIGVPSALLGGWFADRFGGRRSRLIVLGGHAGALALAGLLFALSAPLPVLLLSIAAWSVFAWALNPPLQASTIEAAPQAPMTAVSLNISGLYLGTAVAAGLGGMIVDGPGPLWIPAVAVLALVLAWVSAAFRVPQHASVNA
>NZ_CP042828.1|WP_147917859.1|3292859_3293984_-|tRNA-2-thiouridine(34)-synthase-MnmA
MRVLAALSGGVDSAVAAARAVDAGHDVVGVHMALSRSRAQHRNGSRGCCSIEDASDARRAADVLGIPYYVWDLSEEFEETVVADFLSEYEAGRTPNPCVRCNEHIKFSALLDRGLALGFDAVATGHYARIVEGPGGGDAPRRELHRARDLAKDQSYVLAVMGAERLARSMFPLGEVASKDEVRAEAAARGLSVSAKPDSYDICFVADGDTQGFLRDRLGERQGEFVDAEGQVVGEHQGAYAYTVGQRRGLGLNRPAADGRPRYVLEVNPAANQVVVGPSELLSVSEIAADGVTWLAEDVPAGEWAQVSVQVRAHGDPVPARVRRDEDALVTVLESPLRGIAPGQSIVVYDGTRVLGQAAISRAGRGAAAQPVGA
>NZ_CP042828.1|WP_147917860.1|3293983_3295192_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MTTYFDHAATTPVRPEAADAYLRASQVAGNPSSLHAAGRAARRVLEEESRESIAADLGADPAEVILTAGGTEADNLAVQGIWRAAAQAGRPGLVISAVEHHAVLETAHHLAAHEGAETRELGVDATGVARIDELEALLAEQGEQIGLISLMWANNEVGTLQPVEQVAALGAAHGIAVHSDAVQAVGQVPVNFAASGLDALSFSGHKLGAPIGIGALLARRDLTISPVQHGGGQERAVRSGTLPVASFAALAAAVHAAAVDLEAEAVRRARLRDRIIAEVLAAVPDAQLRGAPGQGRLPGNAHFTFTGTDSDALLFTLDAAGVCASSGSACQAGVQQASHVLLAMGADDGAARSALRLTVGWDSTEADVDALLVALPEAVARARAAYRPRPSQRTGAITKEAS
>NZ_CP042828.1|WP_147917861.1|3295263_3296325_+|GNAT-family-N-acetyltransferase
MSRLTPAADPAVADGLTIRPIDLGSDADLDAINRINAADEELAFGASTAPTVEQTRADAANTTYWRQHRLLAERDADGHPEAVGTGWIGLPLAENTDQAMVAPVVHPDHRGQGVGTALLTGLAQIARDAGRTMLSAWGAVPLDGDVDDPDLPANRLAVRFGMSRKNVAVTRVLDLPVDPNLLDRLWARAEPHLDGYRILSWTDRTPAEHLEAYGVLLRQLELDEPDEDVVHEAPEYTPERIRIAEDRKARKGLRSLVAVALAPDGSFAGNSVVEFHGGAATTLGFQENTLVMPDHRGHRLGYALKVTTHRMLASHAPRLRRLATWNSHVNPWMIQINEDLGYRAIGREVTYQG
>NZ_CP042828.1|WP_168211790.1|3296315_3297302_-|LacI-family-transcriptional-regulator
MTVDLRAVASGARVSVSTASRALSRPDLVNPRTADRVREVAAALGYAPNAAGVALRSGRYGGLTIMLHNLANPLFARLVTRIQHYAQERGLGVQIVDSQGTAELEQERIRSLLNRVDGIIAVAPRLSDEALASAAARLPLVVVNRHVTGVTSVTLDVPTGLSRAVDHLAALGHRHIAYVSGPTRTWSDERRRRRVHDRARFHDMRVESLGPLAPVFRSGLTVAEEVMASGVSAVIAYNSLIALGLAYRLRIDGIDLPTDLSIVAGDDMETRGMEAPTLTAVHLPIDEAASRAVDLLGEIIAGRTDIEAVQIATPLLLGDSTRAVAAQP
>NZ_CP042828.1|WP_168211791.1|3297324_3298362_-|adenosine-deaminase
MNAVSEFLYRLPKAEVHCHFVGAIPADVAWRIATRNEVALPATSAADLYVYDNFHDFIERYMRIATAFRKPSDFAEAMYAILDDGLRHGNVQYREVFFNPTDHYSGGLSYAEMLAGLVEGITAAETDLGVRCRLIPSINRMESAQVALGLVEEVAAHRRDEVIGIGLDAAEPAGPPERFVEAFQLAGRSGLRRTAHACEDYAGLDGGPPANAIACLDELGCDRLDHGYNILADPTVVSRCRESGVPFTVCLPGSNPALRADRVASIRSMMAAGLPVSLHSDDPTMHRTTPGEVYQLGAGSLGLDTSAMAELALAALDAAWLDDGERHELRAAFQHETAALAAELF
>NZ_CP042828.1|WP_168211792.1|3298533_3299865_+|NCS2-family-permease
MRTPEHDAPPGALNRWFRIQQRGSSVRTEVIAGFTTFATMAYVLAVVPGILEAGGVPRAAVTVAIIVMAAVSTLAMGLFTNRPLALAPGLGSVAFIAFTLSAVEGIGWQTSMGMVFISGIAFVLLTIFGLREIIAAIIPKEIKTAIGAGVGLFICFIGFRSGGLVQANESSNALVLANLGSSEAILALIGLALVLILYLRKVPGGLLIAILAATAIGIPLGVTTLPDSWFQLPTGLGEVAFQLDIVGALNFSFFPYIFALFVADFFSTLGTLFAVGAKGNFLDKDGNFPEINKPFLVDSGSTVVGSLFAVPVMTTYVESTSGVEAGGRTGLTAVTTGGLFLATLLFTPVALMIPEQATAPVLILVGLLMLQPLREIDMTNLAAALPAFFTIVVTIFSFNIGTGIAAGMVSYVAAKVIVGEIRSIPVGMWVLLVPLVYYFTTLA
>NZ_CP042828.1|WP_147917865.1|3299848_3300133_-|hypothetical-protein
MYPTAKKCVIWAVCLFVFGALAMAWTTDLYMLIADRMGANAQVGTAVLTTVLNGLRWSLFPTGAALIGAAVVIQALSSDSAASRDGSGPARRES

Crispr_ID: NZ_CP042828_12

• CRISPR_ID: NZ_CP042828_12
• CRISPR_location: 3328157-3328221
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_12

Consensus_repeat	Method
GCGCTCGGGTCTTCGCTCGCGTC	CRISPRCasFinder

spacers of NZ_CP042828_12

>12.1|3328180|19|NZ_CP042828|CRISPRCasFinder
TTCACTGGCGCTCGGGTCT

CRISPR arrays and Neighbor proteins around NZ_CP042828_12

CRISPR arrays

The CRISPR arrays of NZ_CP042828_12

>merge|NZ_CP042828|12|3328157-3328221|CRISPRCasFinder
GCACTCGCACTCTCGCTCGGGTCTTCACTGGCGCTCGGGTCTTCGCTCGCGTCTTCGCTGGCGCT

>NZ_CP042828|12|11|3328157-3328221|CRISPRCasFinder
GCACTCGCACTCTCGCTCGGGTC	TTCACTGGCGCTCGGGTCT
TCGCTCGCGTCTTCGCTGGCGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147919535.1|3334869_3335172_-|DUF4235-domain-containing-protein	unknown	unknown	gnl|CDD|379422
NZ_CP042828.1|WP_147919533.1|3332108_3332786_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NZ_CP042828.1|WP_147917888.1|3336302_3337994_-|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|340868
NZ_CP042828.1|WP_147917887.1|3335401_3336226_+|ammonia-dependent-NAD(+)-synthetase	unknown	unknown	gnl|CDD|234831
NZ_CP042828.1|WP_147917885.1|3331413_3332112_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917874.1|3316666_3316996_-|SnoaL-like-domain-containing-protein	unknown	unknown	gnl|CDD|378915
NZ_CP042828.1|WP_147917879.1|3325018_3325945_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|225660
NZ_CP042828.1|WP_147917882.1|3328839_3330441_+|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NZ_CP042828.1|WP_147917877.1|3319522_3321292_+|maltose-alpha-D-glucosyltransferase	unknown	unknown	gnl|CDD|274140
NZ_CP042828.1|WP_147917883.1|3330450_3330942_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NZ_CP042828.1|WP_147917880.1|3325975_3327034_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917886.1|3334473_3334782_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147919532.1|3312119_3312929_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381364
NZ_CP042828.1|WP_147917875.1|3317161_3317377_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917872.1|3312967_3313747_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP042828.1|WP_147917884.1|3330998_3331424_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917873.1|3313776_3316368_-|alpha-glucan-family-phosphorylase	unknown	unknown	gnl|CDD|340852
NZ_CP042828.1|WP_147917878.1|3321288_3324888_+|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl|CDD|235445
NZ_CP042828.1|WP_168211794.1|3332950_3334438_+|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|367817
NZ_CP042828.1|WP_147917876.1|3317510_3319526_+|DUF3416-domain-containing-protein	unknown	unknown	gnl|CDD|200482

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147919535.1|3334869_3335172_-|DUF4235-domain-containing-protein	gnl|CDD|379422	pfam14019, DUF4235, Protein of unknown function (DUF4235). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 88 and 119 amino acids in length.	1.17047e-23
NZ_CP042828.1|WP_147919533.1|3332108_3332786_-|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	1.07658e-17
NZ_CP042828.1|WP_147917888.1|3336302_3337994_-|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|340868	cd06179, MFS_TRI12_like, Fungal trichothecene efflux pump (TRI12) of the Major Facilitator Superfamily of transporters. This family includes Fusarium sporotrichioides trichothecene efflux pump (TRI12), which may play a role in F. sporotrichioides self-protection against trichothecenes. TRI12 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.93058e-66
NZ_CP042828.1|WP_147917887.1|3335401_3336226_+|ammonia-dependent-NAD(+)-synthetase	gnl|CDD|234831	PRK00768, nadE, ammonia-dependent NAD(+) synthetase.	1.36836e-160
NZ_CP042828.1|WP_147917874.1|3316666_3316996_-|SnoaL-like-domain-containing-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.17777e-09
NZ_CP042828.1|WP_147917879.1|3325018_3325945_-|tetratricopeptide-repeat-protein	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	9.17684e-39
NZ_CP042828.1|WP_147917882.1|3328839_3330441_+|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	1.9475e-12
NZ_CP042828.1|WP_147917877.1|3319522_3321292_+|maltose-alpha-D-glucosyltransferase	gnl|CDD|274140	TIGR02456, Trehalose_synthase, trehalose synthase. Trehalose synthase interconverts maltose and alpha, alpha-trehalose by transglucosylation. This is one of at least three mechanisms for biosynthesis of trehalose, an important and widespread compatible solute. However, it is not driven by phosphate activation of sugars and its physiological role may tend toward trehalose degradation. This view is accentuated by numerous examples of fusion to a probable maltokinase domain. The sequence region described by this model is found both as the whole of a trehalose synthase and as the N-terminal region of a larger fusion protein that includes trehalose synthase activity. Several of these fused trehalose synthases have a domain homologous to proteins with maltokinase activity from Actinoplanes missouriensis and Streptomyces coelicolor (). [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP042828.1|WP_147917878.1|3321288_3324888_+|1,4-alpha-glucan-branching-protein-GlgB	gnl|CDD|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NZ_CP042828.1|WP_147919532.1|3312119_3312929_+|aldo/keto-reductase	gnl|CDD|381364	cd19138, AKR_YeaE, Escherichia coli YeaE and similar proteins. Escherichia coli YeaE is the prototype of this family. It acts as an aldo-keto reductase (AKR) that catalyzes the reversible reduction of ketones to the respective alcohols using NAD(P)H as a hydride donor.	1.29743e-135
NZ_CP042828.1|WP_147917872.1|3312967_3313747_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	7.71067e-08
NZ_CP042828.1|WP_147917873.1|3313776_3316368_-|alpha-glucan-family-phosphorylase	gnl|CDD|340852	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase. This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism.	0
NZ_CP042828.1|WP_147917883.1|3330450_3330942_-|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.93635e-07
NZ_CP042828.1|WP_168211794.1|3332950_3334438_+|glutamate--cysteine-ligase	gnl|CDD|367817	pfam04107, GCS2, Glutamate-cysteine ligase family 2(GCS2). Also known as gamma-glutamylcysteine synthetase and gamma-ECS (EC:6.3.2.2). This enzyme catalyzes the first and rate limiting step in de novo glutathione biosynthesis. Members of this family are found in archaea, bacteria and plants. May and Leaver discuss the possible evolutionary origins of glutamate-cysteine ligase enzymes in different organisms and suggest that it evolved independently in different eukaryotes, from an ancestral bacterial enzyme. They also state that Arabidopsis thaliana gamma-glutamylcysteine synthetase is structurally unrelated to mammalian, yeast and Escherichia coli homologs. In plants, there are separate cytosolic and chloroplast forms of the enzyme.	1.92339e-07
NZ_CP042828.1|WP_147917876.1|3317510_3319526_+|DUF3416-domain-containing-protein	gnl|CDD|200482	cd11344, AmyAc_GlgE_like, Alpha amylase catalytic domain found in GlgE-like proteins. GlgE is a (1,4)-a-D-glucan:phosphate a-D-maltosyltransferase, involved in a-glucan biosynthesis in bacteria. It is also an anti-tuberculosis drug target. GlgE isoform I from Streptomyces coelicolor has the same catalytic and very similar kinetic properties to GlgE from Mycobacterium tuberculosis. GlgE from Streptomyces coelicolor forms a homodimer with each subunit comprising five domains (A, B, C, N, and S) and 2 inserts. Domain A is a catalytic alpha-amylase-type domain that along with domain N, which has a beta-sandwich fold and forms the core of the dimer interface, binds cyclodextrins. Domain A, B, and the 2 inserts define a well conserved donor pocket that binds maltose. Cyclodextrins competitively inhibit the binding of maltooligosaccharides to the S. coelicolor enzyme, indicating that the hydrophobic patch overlaps with the acceptor binding site. This is not the case in M. tuberculosis GlgE because cyclodextrins do not inhibit this enzyme, despite acceptor length specificity being conserved. Domain C is hypothesized to help stabilize domain A and could be involved in substrate binding. Domain S is a helix bundle that is inserted within the N domain and it plays a role in the dimer interface and interacts directly with domain B. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0

Protein sequences

>NZ_CP042828.1|WP_147917880.1|3325975_3327034_-|hypothetical-protein
MSRISRRASAGLTALAALSLLAGCAMPVPSPDPQPEAPESMPALDEPRIDRVLEELGEAISAADEEGDAELASDRMANPALRIREAEYALAQATADGDGTYSPRTLITSPQVEIVSAAEDWPRTIMVVTEIAEGANVPLLLTLQQEDPRSPYQLHHWVRLLPGSEMPPTAVPATGSAQVADDASGYLVSPTDAIAQYADVLTEGDGSDFAGSFALEDDEFYGLVQDEAENLDVVDEAGTFSQRTHATDAPVLTMATEDGGYIVVGEMRTRQKFTKTISGSEITVPSPHIEALDSEDGLLEYLDDSLIASFRTMVAMYVPAEDAEDGAVTVLGAERVLTGVSRECPRDEERCA
>NZ_CP042828.1|WP_147917879.1|3325018_3325945_-|tetratricopeptide-repeat-protein
MTQQPPPSINLHGAVDLSALAAPPPPPPSADTPAGLVLDVTEETFNDVVQQSNQVPVVVLLWQVGEGQSIQLNTTLQTLVTEQAGKFVLARIDVAANPRLAQVFQVQAVPAALAVIKGQPVPLFQGAPAAEQVRPVLDQLLQLAQEQGVTGTVDAGQEPGADDQEPAEPPLPPHIQAAYDAIEADDLDGAVAAFEGAIAENPADAEAVAGLAQVQLLQRIGGLDPAQVLQHATEAPAGDLDAQLPAADLEVAGGRLAEGFARLLQVIRVTAGEDKERARVRLLELFRLAADDAPEVVKARRDLAIALY
>NZ_CP042828.1|WP_147917878.1|3321288_3324888_+|1,4-alpha-glucan-branching-protein-GlgB
MSEPDSSLLLDLIGDWVREQRWFPAKDAADAELDILTSFDLPDPWDEAACTVVLLVLRRGGQEPAVLQVPLVATASWAPDHGLIASLGKREVLVDGPHHPAFLRAWLAAATPRPGATIALAELDPSAARVHTGEQSNTSVRIPGRVADGETATKAAVLKIFRVLAAGPNPDLELVAALREAGWRHVPDVLAGYSRSWPDPSGSAVAGDLGVLTAFVPAAEDGFELACGYARTGRDLTPLATDLGACVAQLHTHLRTAVPAETGNRGGPDLAGQLRQRAQWALDQVPALGVFADGIEAVIAGVVGAQVPPDQRIHGDLHLGQVLHGTDGWYVLDFEGEPLRPLAERRSADQPLRDVAGMLRSFDYAAAVGRAATAAWAEEARGSFLAGYRAERADLDETVLRALELDKALYEAVYEQKNRPDWLPIPLTGIRRLTEEQTVAENAPPAGERLLAGIFPSPSRSVSAPAEASQAAPSTAEARPAPVPDSVLATLATGAHFAPHDVLGPHLDTGSGVLTIRVVAHLATAVQVRTAAGSHPAEHVRDGIWAAAFDAEEVPDYRLQVTYADNEVEVDDPYRFLPTLGEVDQHLIAEGRHEKLWEVLGSWVRHYPGTLGEVSGVSFAVWAPNARAVRVVGDFNGWDGRGAMMRSLGSTGVWEVFLPGLAAGERYKYEICVADGSWHMKADPMARATEVPPATASVVTESRYTWADQDWMAARAEQDPHSGPLSVYEVHLGSWRKELSYLELAEQLVEYVTWMNFTHVELLPVAEHPFGGSWGYQVTSYYAPTSRFGSPDEFRYLVDALHRAGIGVILDWVPAHFPKDAWALARFDGTPLYEDPDPLRGEQKDWGTYVFNFGRNEVRNFLVANAVYWLTEFHVDALRVDAVASMLYLDYSREAGQWRPNARGGRENLEAIQFLQEANATAYRAAPGTMMIAEESTAWPGVTTPTEHGGLGYGLKWNMGWMNDTLRYLAEEPINRRYHHGELTFSLVYAFSEQFVLPLSHDEVVHGKGSLWQKMPGDLWAKLAGVRLLLAYQWTHPGKKLLFMGGEFAQNTEWNEAQSLNWELGDTPGHAGVREMLRRLNQVYADHPALWAEDFSPAGFEWLEANDGDHNVLAYLRKGRGEDLVVVANFAGSPHEDYRVGVPTGGTWVELLNTDHLDFGGSGVVNTAERPAEEVPWHGRPQSIQLRVPPLGVTILRRV
>NZ_CP042828.1|WP_147917877.1|3319522_3321292_+|maltose-alpha-D-glucosyltransferase
MSTAFAPARRPGLTEDPHWYRTAVFYEVLPRAFSDSDGSGTGDLRGLIARLDYLQWLGVDCLWLPPFYPSPLRDGGYDVSDYTAVADEYGTIEDFTELVAAAHERGIRIIIDLVMNHTSDTHPWFQSSRSNPDGPYGDFYVWGEDPERYPDARIIFVDTEVSNWTFDPARRQYFWHRFFSHQPDLNYENPRVRAAMFDVVRFWLRTGVDGFRLDAVPYLFEEEGTDCENLPATHEFLAAVRAMVDAEFPGRLMLAEANQWPADVVAYYGTEDAPECHMCFHFPVMPRIFYALREQSARSIAQILADTPPIPAGAQWGTFLRNHDELTLEMVSTEERAAMYGWYAPEARMRANVGIRRRLSPLLDNSRAEVELAHALLLSLPGSPCLYYGDEIGMGDNIWLPDRDAVRTPMQWTPDRNAGFSAATDPGRLYLPVVQNLTNHYNQLNVEAQLAIPTSLLHWVRGILEVRRAHPVFGLGEYVPLDSDNDAVLAFLRRDESETMLCVANLAATPRSAVVSLPGLAGRSLRDIFGGTSFPRVATSSGSNRAEPTTAQPADTGDSPSAGVGRGEDGELTLTLGSRDFFWLTVEQP
>NZ_CP042828.1|WP_147917876.1|3317510_3319526_+|DUF3416-domain-containing-protein
MTTPSPTPAAPIGRIPVLDVGPSVENGRWPTKAVVGEAIPVRATVFREGHDAVAATAVLVRPDGTDHSRAQMRDISPGLDRYGAWLVPDAEGDWGFRVEGWSDPYGTWRHDAVLKVHADVDTEVMLTEGALLLQRAAAELTLTDAQSQVLTDAVTALQDAGRPALARLAAGTAPEVQEVLTEVPLRDYVSTSATYPLVVHRERALYGSWYEMFPRSEGAHQDETTGEWHSGTLRTAAERLPGIAAMGFNVVYLTPVHPIGTTNRKGRNNTLVAEPADPGSPYGIGAADGGHDAIHADLGTFDDFDHFVARARELGLEVALDIALQASPDHPWASEHPEWFTTRADGSIAYAENPPKKYQDIYPLNFDNDPEGIYTAVRAMLQVWIDHGVTLFRVDNPHTKPLTFWEQILADVARAHPEVIFLSEAFTRPAMMRTLGMLGFHQSYTYFTWRHSKTELAEYFTEVSGDLAAVMRPAFWPTTHDILTPYMQQGGPAAFAIRAVLAATGSPTWGIYSGYELAENVARPGAEEQIDNEKYEYKPRDWEGATRTHGLTDLLTQLNRIRREHPALQRLRNLTVHPTTDDATFCFSKHLPAAHSPTGQADTVIVVVNLDPFTSRDSLIHLDTAALGLGEQGEFTAHDELTGESYAWGPVPFVRLDPHGRCAHILEVRHR
>NZ_CP042828.1|WP_147917875.1|3317161_3317377_-|hypothetical-protein
MDVKVITVDGETFEVRERGRECDFLWVGGRHQGDYGFGSTRNEDGPRSMADHRKSIRAFLDGVDPVTGYLE
>NZ_CP042828.1|WP_147917874.1|3316666_3316996_-|SnoaL-like-domain-containing-protein
MHNIELPRAIRAFVEATNAGDSDTFVAAFTPDGSVYDWGREFTGRDGVRAWDRTDNIGVQAHFEVLGIEDGDRPDTFVLTARVTGNGYNGTGPLVFRLRDGLVAHLRIG
>NZ_CP042828.1|WP_147917873.1|3313776_3316368_-|alpha-glucan-family-phosphorylase
MRAIRRFTVRTVLPEPLAALDELALNLRWSWHEPTRALFAGIDAQLWDEVHGDPVRLLGSLSPERLVELAADDGFVTRTRELAADLRTYLGDERWYQGEQRRRESAGEAALPASIAYFSAEFGITGALPQYSGGLGILAGDHLKSASDLGAPIVGVGLLYGAGYFRQSLTRDGWQAETYPVLDPDSLPLSLLREADGTPARISLPLPGGRMLHAQVWRADVGRVPLLLLDSNVPENDDHSRRVTDRLYGGTSEHRLNQELLLGMGGVKALRLHSRLTGGPEPEVYHCNEGHAGFLGVERIRELLAGSDLDFEAAREAVRAGTVFTTHTPVPAGIDRFGADLIAEYFGGGNEVPGISVEQVLALGREDYTGGDPAVFNMAVMGLRLAKRANGVARLHGRVSRRMFQHLWPGFDADEVPITSITNGVHAQTWTDPMFAEAQREYFSPDEIADGSGWYKETGGIDNATLWQLRRAQRERLVADARVRSRKSWLQRGASPAELGWVDGILDPDVLTIGFARRVPTYKRLTLMLRDTDRLRRLLLHPERPIQIVVAGKSHPADEQGVRLIQQLVQFADAEDVRHRIVFLPNYDIEMAQSLYPGCDVWLNNPLRPLEACGTSGMKAALNGGLNLSILDGWWDEMFDGENGWAIPTADGVTDADRRDDLESAALYDLLENTVAPRFYDRTDGLPVQWLANVRHTLATLGPKVQATRMVREYISELYTPVAESARELRADGGAGAMALADWKTRVHQAWSGVRVEHVESEGLHDTVQVGDHVTVRAFVSLGGLVPEDVQVQMASGRVGDDDEIDEFEIVPLALTDSYEGGRYQFARELTLSRSGPFGYTVRIVPMHPGLAGFAELGLVASA
>NZ_CP042828.1|WP_147917872.1|3312967_3313747_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MNHEDVIVAEAARFADVLATADPHAQCPTCPEWNSADLLWHLTTVHRFWAAVLEQDLRTDEQAEAVESGEEQQPSAISAMLPERSAATETLVDQLRRLGDDQPRWTWWEPEQTVGFTRRMQVCEATMHRIDAELTARVDAGPIDDEVATLCLDHCVDVMWGWMPDWATWQAETVAELLAPDTGGRWLVEVGHWFGTGPESGREFDVPRAVRAGAGAAAPTVRVTAPVEQLARWAWRRQGEAEVTGDTAALDALLAQGIQ
>NZ_CP042828.1|WP_147919532.1|3312119_3312929_+|aldo/keto-reductase
MATADGQVVCAVGQGTWYLGDDPGTREEEIAALRAGIEAGLNLIDTAEMYGGGRSEDLVGAAIAPVREQVYLVDKVLPSNASRSGTIAACERSLRALGTDWIDLYLLHWPGPYPEAETVAAFEELIERGLIRSWGVSNFDPGDLAVLPAGPLVNQVLYNPSRRGVEVDLLPAHRAAGITTMAYSPIEQGRLLDDPTLAGVARRHGVSVAQVLIAWAVREGGVIAIPKASTVAHVRENAAALELRLDADDLAAIDAAFPAPDGPVPLEIL
>NZ_CP042828.1|WP_147917882.1|3328839_3330441_+|hypothetical-protein
MADDSSTFPVVMRGYDRAQVDQRIHALQRQLAEARTQVESLDASSMQISGELADAQAQLKEAEKPSYAGLGARIEQLLRSAEEQSAGVLTQANQQAKDITARSRAAAEELTSQAENEAGELLANARRDSESSTQRAASQAEGTLLAAQRKAEELVASSEREAARISSVARTEQSEKHASLERELGTARAEAEKEIAERKVESERTARELKSTSETEAEEVRSRAKAEAQAAREEAQREASSTIAQAEDEAAEILRQANADAEEIRRSVAQMREDAELEIAERRAASEESDAALHAQAKADTDEMIASAQAHAQEAEARVAEALAKAEELRSSAETQAEQILADARSSADRVTRETREAADRYRADTAAETDQERRTAQRQVDELDRQRESITGYLDELRALLGAGQVAEAADLAVPEADPEAANGAEAATEDAEADSASAAEDAEVLAEEPAAENASADLTEDAVVADEPSGVDQTADAHAVEPDAATADAADLDTAAAETPEEPAQASSTADGDTEVMDAVVDGEQESSKQS
>NZ_CP042828.1|WP_147917883.1|3330450_3330942_-|GNAT-family-N-acetyltransferase
MTAAPPAARIRPAHAGDADALHELHCDTWREAYAELVPDEVFSHQREHGLSEWQARLSDPTGDAVWLAHRDGAAVGFASATATGTQEVRALRLWGLYVRATEYGLGTAANLLQLAVGDAPCYLWVAAGNPRAVAFYRKHGFDLDGTEQQVQRWGDLRTVRMVR
>NZ_CP042828.1|WP_147917884.1|3330998_3331424_+|hypothetical-protein
MSTDWAQQRTEAAREHERRLEQRRRAQSERARALLHTFVAAARAADLPTEPLVVKGYGNRGSARTPLRGWYLRVDRTSAVTPTGDFYVLTAPLTAWERLRGTSPEPSDPPLVLGAGGKDGDSIDLADALTRLLPGWDAATP
>NZ_CP042828.1|WP_147917885.1|3331413_3332112_-|hypothetical-protein
MRARRALRRHADELGAPIAVHYSRPGVWTKLICLAFWLLTLSSAAVNPDPDPMLNLLFPAVMAVLVLGFYALIRGETLAVCERGLLIGSTALFLRPYVLRYEEIMPGSITPVTGTRRIGLSLGIPPKGIFHTIRSGAWIHQGIYLIGPPPLQPQFSRGKILRITTNGRAWIWFAGTGRTPPEQVTAQIAAAAHRAGFVQLADGAARAVPQHLNGSVAHSRAVLPGFTYGIRV
>NZ_CP042828.1|WP_147919533.1|3332108_3332786_-|alpha/beta-fold-hydrolase
MWAYTISAAPQLPVITIDAPGFGASPPVDGGLDAYADAVAATLEHAGMARAVVAGLSMGGYAALELAQRHPHLLAGIGLLDTKAGADPQDKRVDRLQMAEDALGEAGARAVAPMLDSLLAPGAPEAVRTEVAGWLRHASPSGIAWAQRAMAARADRLATLTRLDVPALVLRGAQDATASLAEHEEMATALGTQVIEVDGAGHLSALESPHEVAAALSDLYARATA
>NZ_CP042828.1|WP_168211794.1|3332950_3334438_+|glutamate--cysteine-ligase
MASVGDEISTQTFSREQRLRYREKVRRCLDVFGEMLAHHHFDSHPALTGLEVELNLVDAGAQPSMKNAQVLAAIADPAFQTELARYNIELNVPPQPLPGDAVLDLEKDIRAALNHADDRAQQHGAQIAMIGILPTLRPEHLTGDWMSPNPRYQALEDAVFAARREDIELDISGPEPLRMLTATLAPESACTSVQLHLQVSPTEFAPHWNAAQILAGPQLALGANSPFLFGKRLWAETRTELFLQATDTRSPELRNQGVRPPVYFGESWITSIFDLFEENVRYFPALLPETTDEDPEAELAAGRTPRLQELRLHNGTVYRWNRPVYDVVDGKPHLRVENRVLPAGPTVSDILANAAFYYGAMEMLAHEDRPMWSRMSFSAAEANFTAGARDGVEAMMYWPGYGEVGWDELVLRLLLPLAAEGLSRRRVASTVIDRFLGIIEARCKLRRNGAWWQTATVAALEDKGMDREQALTEMLLRYMDGMHSNEPVHTWEVPA
>NZ_CP042828.1|WP_147917886.1|3334473_3334782_-|hypothetical-protein
MARRSRKRPYGEPHPELDADALLRGGARVESGGNGQRWNVRSVTGSAKSYLCPGCQQQIPPGVAHVVAWGEDHLFGADAALADRRHWHNGCWRARDRRGPLR
>NZ_CP042828.1|WP_147919535.1|3334869_3335172_-|DUF4235-domain-containing-protein
MSAEKNKNPNKSAKILYQPFGLVTSMLAGLVASQVFKQIWKRAVPGEHDDPPNALESEYTFKEVVLGALIQGAIFAVVKAAVSRGGARAFERWTGEWPGD
>NZ_CP042828.1|WP_147917887.1|3335401_3336226_+|ammonia-dependent-NAD(+)-synthetase
MRELQKVIVAEMGVQPDIDPAAEAERRVAFLSEYLAATGARGYVLGISGGLDSTLAGRLAQRAVQQRRAEGGEAVFVAVRLPYRVQFDEEDAQAALEFVAADEMITYNVAPAVDAFESEYLTATGHPISDFTKGNTKARLRMVAQYAAAGDRGLLVIGTDHGSESVTGFFTKFGDGAADVLPLFGLNKGQNRRVLRAIGGPERLWSKEPTADLLDGLPGRPDEVELGVTYEYIDAYLEGREVPDEVAETIEAAWRRTRHKRTVPVTPQHTWWKG
>NZ_CP042828.1|WP_147917888.1|3336302_3337994_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTTTSRDARQGSASAPVSAVPKGTLVPLFIGLMLAMLLASLNQTVFATALPTIVGELNGVSSMVWVITAFILATTIAMPIYGKLGDQIGRKPLLIFAISVFMIGSVVGGLSADMGTLIVARVIQGLGGGGLMILSQAAIADVVPARERGKYMGVMGGVFALSSVIGPLLGGWFTDGPGWRWAFWINLPIGVLALLAATFFLKLPRQHGRPTLDWGGMALIATATTSMVLVTTWGGGTYAWTDPVVLGLIALFVVTAVAFVLVERRTAEPLIPMTLFKERNFVLTTIAGLLIGVAMFGALGYMPTYLQMSFGLDATVAGLAMIPMMAAMLITSTTSGALVSRFGRYKWYPVAGALSIAAAMVLLSQMDPHEPLWLACAYLGLLGVGLGLAMQNLVLIVQNTFPITMVGTATASNNYFRQIGATLGSSLVGSLFASRLVSLMAERLPAASAGQMGSADSLTPAVVSGLPEPVHDLVITAYSDALTPIFLWIAPLGLIAAVLLMFVHEKPLATRIERSSEAEPTTGSLSVASEQPSRTTVPSDPAEADDPGPESERTSTDELAPTR

Crispr_ID: NZ_CP042828_13

• CRISPR_ID: NZ_CP042828_13
• CRISPR_location: 3435384-3435477
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_13

Consensus_repeat	Method
TTCGGTCAGGCCAGCGGACAGGCCGCCGGTCAAG	CRISPRCasFinder

spacers of NZ_CP042828_13

>13.1|3435418|26|NZ_CP042828|CRISPRCasFinder
ACGGACCTCCGCCGTCGCCCGGCTCA

CRISPR arrays and Neighbor proteins around NZ_CP042828_13

CRISPR arrays

The CRISPR arrays of NZ_CP042828_13

>merge|NZ_CP042828|13|3435384-3435477|CRISPRCasFinder
TTCGGTCAGGCCAGCGGACAGGCCGCCGGTCAAGACGGACCTCCGCCGTCGCCCGGCTCATTCGGTCAGGCCAGCGGACAGGCCGCCGGCCAAG

>NZ_CP042828|13|12|3435384-3435477|CRISPRCasFinder
TTCGGTCAGGCCAGCGGACAGGCCGCCGGTCAAG	ACGGACCTCCGCCGTCGCCCGGCTCA
TTCGGTCAGGCCAGCGGACAGGCCGCCGGCCAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147919545.1|3433228_3433900_+|DUF4129-domain-containing-protein	unknown	unknown	gnl|CDD|379261
NZ_CP042828.1|WP_147917971.1|3448372_3449539_+|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|185017
NZ_CP042828.1|WP_147917965.1|3438108_3439626_-|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP042828.1|WP_147917963.1|3433896_3435081_+|DUF4350-domain-containing-protein	unknown	unknown	gnl|CDD|379527
NZ_CP042828.1|WP_147917966.1|3441830_3443144_-|Na+/H+-antiporter-NhaA	unknown	unknown	gnl|CDD|184855
NZ_CP042828.1|WP_147919547.1|3440928_3441684_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NZ_CP042828.1|WP_147917956.1|3424412_3425096_-|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl|CDD|238308
NZ_CP042828.1|WP_168211800.1|3426340_3427327_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147917962.1|3432287_3433226_+|hypothetical-protein	unknown	unknown	gnl|CDD|370818
NZ_CP042828.1|WP_168211802.1|3427754_3429215_-|hypothetical-protein	unknown	unknown	gnl|CDD|237448
NZ_CP042828.1|WP_147917968.1|3444887_3445823_-|glycine-betaine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270357
NZ_CP042828.1|WP_168211799.1|3425403_3426207_-|ComF-family-protein	unknown	unknown	gnl|CDD|223970
NZ_CP042828.1|WP_147917967.1|3443154_3444633_-|adenosylhomocysteinase	unknown	unknown	gnl|CDD|377487
NZ_CP042828.1|WP_168211801.1|3427533_3427773_-|hypothetical-protein	unknown	unknown	gnl|CDD|237448
NZ_CP042828.1|WP_147917961.1|3430908_3431592_-|response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP042828.1|WP_147917969.1|3445860_3446820_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|226644
NZ_CP042828.1|WP_147917960.1|3429211_3430936_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP042828.1|WP_147917964.1|3436627_3437920_+|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
NZ_CP042828.1|WP_147919546.1|3435653_3436628_+|AAA-domain-containing-protein	unknown	unknown	gnl|CDD|223786
NZ_CP042828.1|WP_147917970.1|3446816_3448088_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226643

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147917971.1|3448372_3449539_+|nucleotide-sugar-dehydrogenase	gnl|CDD|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP042828.1|WP_147917965.1|3438108_3439626_-|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.73096e-33
NZ_CP042828.1|WP_147917963.1|3433896_3435081_+|DUF4350-domain-containing-protein	gnl|CDD|379527	pfam14258, DUF4350, Domain of unknown function (DUF4350). This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length.	0.000241153
NZ_CP042828.1|WP_147917966.1|3441830_3443144_-|Na+/H+-antiporter-NhaA	gnl|CDD|184855	PRK14853, nhaA, pH-dependent sodium/proton antiporter; Provisional.	9.52081e-159
NZ_CP042828.1|WP_147919547.1|3440928_3441684_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.17866e-11
NZ_CP042828.1|WP_147917956.1|3424412_3425096_-|ribosome-associated-translation-inhibitor-RaiA	gnl|CDD|238308	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site. RaiA is also thought to counteract miscoding at the A site thus reducing translation errors. The RaiA fold structurally resembles the double-stranded RNA-binding domain (dsRBD).	2.78288e-22
NZ_CP042828.1|WP_147919545.1|3433228_3433900_+|DUF4129-domain-containing-protein	gnl|CDD|379261	pfam13559, DUF4129, Domain of unknown function (DUF4129). This presumed domain is found at the C-terminus of proteins that contain a transglutaminase core domain. The function of this domain is unknown. The domain has a conserved TXXE motif.	2.05061e-05
NZ_CP042828.1|WP_147917962.1|3432287_3433226_+|hypothetical-protein	gnl|CDD|370818	pfam10110, GPDPase_memb, Membrane domain of glycerophosphoryl diester phosphodiesterase. Members of this family comprise the membrane domain of the prokaryotic enzyme glycerophosphoryl diester phosphodiesterase.	0.000102423
NZ_CP042828.1|WP_168211802.1|3427754_3429215_-|hypothetical-protein	gnl|CDD|237448	PRK13614, PRK13614, lipoprotein LpqB; Provisional.	8.03904e-55
NZ_CP042828.1|WP_147917968.1|3444887_3445823_-|glycine-betaine-ABC-transporter-substrate-binding-protein	gnl|CDD|270357	cd13639, PBP2_OpuAC_like, Substrate binding domain of Lactococcus lactis ABC-type transporter OpuA and related proteins; the type 2 periplasmic binding protein fold. This subfamily is part of a high affinity multicomponent binding-protein-dependent transport system specific to betaine compounds for osmoregulation. The periplasmic substrate-binding domain, which is often fused to the permease component of the ATP-binding cassette transporter complex, is involved in uptake of osmoprotectants (also termed compatible solutes) such as glycine betaine and proline betaine. Many microorganisms accumulate these compatible solutes in response to high osmolarity to offset the loss of cell water. This domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.8066e-97
NZ_CP042828.1|WP_168211799.1|3425403_3426207_-|ComF-family-protein	gnl|CDD|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	2.32305e-17
NZ_CP042828.1|WP_147917967.1|3443154_3444633_-|adenosylhomocysteinase	gnl|CDD|377487	pfam05221, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.	0
NZ_CP042828.1|WP_168211801.1|3427533_3427773_-|hypothetical-protein	gnl|CDD|237448	PRK13614, PRK13614, lipoprotein LpqB; Provisional.	0.000478222
NZ_CP042828.1|WP_147917961.1|3430908_3431592_-|response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.67247e-84
NZ_CP042828.1|WP_147917969.1|3445860_3446820_-|ABC-transporter-permease-subunit	gnl|CDD|226644	COG4176, ProW, ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism].	1.67806e-107
NZ_CP042828.1|WP_147917960.1|3429211_3430936_-|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.39025e-54
NZ_CP042828.1|WP_147917964.1|3436627_3437920_+|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	9.62147e-42
NZ_CP042828.1|WP_147919546.1|3435653_3436628_+|AAA-domain-containing-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.99125e-96
NZ_CP042828.1|WP_147917970.1|3446816_3448088_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl|CDD|226643	COG4175, ProV, ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism].	1.44474e-164

Protein sequences

>NZ_CP042828.1|WP_147917963.1|3433896_3435081_+|DUF4350-domain-containing-protein
MRAAPATFDALGRRASAPEDESTKQRSGRRSLMFVAIALVALILAAVLLSRLSPDTSQAPLSSTNPDEVGARAAAQILGEQGVQVTEVSSTDAALADARPDATLLITGADELRPEQQQALADVPADVVLIGLGYGDLAELTDRVQVEGGGGQSTYPAECANEHAQAAEGLSTSGPSLTTQADIEGCFPLDDTGAAVAFGTWTEEDGQTWSVLPNPHPLTNAGLDEAGNAALVLRILGQHEHLTWYVPDPNDDFGMTEEGTPSLVPGVVAVQVLIALVAFAYWRGRRLGRVVVEPLPVIVRATETTRGRGRLYRRGRAHEHAAAALRAGTISRIAARLGLPRTATGPDVVEAFARATGRPADAIDSLLYGPPPTDDASLVTLTQALDTLESEVHR
>NZ_CP042828.1|WP_147919545.1|3433228_3433900_+|DUF4129-domain-containing-protein
MLGPWSRDVPLTPSADDAREWAQAELAKAIYNDEPTLLERLLFWLSELWRKLMSWNEDVGPVVVPLVVLAVVALIVAAALLIGGPIRRRRARQQGASAVVLDGDERTSGELRSAAEAAAAAGDFSRAVLERFRAIVRSLDERVVLEDRAGRTAYEAATEAGRGLPDCAADLLVVSHLFDAVCYGDRQAERDDYDRVVAVDDAVAAARPVQLAGMEHDEPAVTG
>NZ_CP042828.1|WP_147917962.1|3432287_3433226_+|hypothetical-protein
MPPAWGPAPQPGIIPLRPLTLGEMYDGAIRSIRTNPAVMFVLSAVLVSLAMLVQGIATWGVFEDLNALVGMDPETMATLDTSSLLATLQSAALGYAISGLVSFLITTILNGLLIHAVSQAVIGRKMNLEEVWHATKRQIPRLLLLSLVVTVLMLAVVAVLVGIIALLALTGSTAAIALGVLVVSLLMLVGILAVATLTVLATPALVLERAGVFTALRRSFTLVKQSFWRVLGIYLLTAILVGILSSIIAYPVAIFGQFIGSDGMYVLNLVANVIALSITTPFMAAVTALLYIDVRMRLEALDVELARAAQES
>NZ_CP042828.1|WP_147917961.1|3430908_3431592_-|response-regulator
MNGRVLVVDDDAALSEMIGIVLQSEGYETAFCSDGAKAVEAYRTEQPDLILLDLMLPGMDGIEICRRIRAESGVPIVMLTAKGDTADVVLGLEAGADDYMAKPAKPTELVARVKARLRNRTTQGTERLPIGDLVIDVPGHRVVRGEEAINLTPLEFDLIVALARKPWQVFTREVLLEQVWGYRHQADTRLVNVHVQRLRAKVEKDPENPEVVVTVRGVGYRAGTPVS
>NZ_CP042828.1|WP_147917960.1|3429211_3430936_-|HAMP-domain-containing-protein
MPGRHARLVNAPAGRERSWWQRAVRTSIQASRWLRRRARVALRAWRHSLRLRVSATTVAVGTLALVLLAVVLADQVRDGLFDQRREQVLADAANGAEQAQQQFDSTTVSSVQDVQQLGDDMVRALQQSSLDAAGVLLLPSPDQSGSGLIQAPATNNALRPVISDELRAQVRDEQFQQWQSVAVPDGSGTVPGIAVGSPVTMPVAGENELYIVYSLASEQAQLSLLQRVLAVGAASLVVLLLVMAWYLTRQVLDPVQQAARTAERLADGHLTERMEVRGRDELATLSKSFNEMATSLQDQIEKLAELSRMQQRFVSDVSHELRTPLTTVRMAAEVLYEARKSFGPSQARSAELLQNQLDRFENLLVDLLEISRFDAGAAVLDVEALDLRVVLDRVAALTEPLAAERGSTIRMQTPEAPVVADADARRVERVLRNLLVNAVEHGEGKDIEVLVGEHETAVAVAVRDHGIGMTPVQAEHVFDRFWRADPARARTLGGTGLGLAIALEDARLHGGTLDAWGTPGEGATFRLTLPRRAGLEIGESPLRLRPERAEATLARANDPAGPAAVPQWEQEEES
>NZ_CP042828.1|WP_168211802.1|3427754_3429215_-|hypothetical-protein
MNRSPRLLAALTALALMAGCASLPTDGAVQPGVEAGQEEGVGYVVAADPQRGAGPDEIVRGFQSAAVAGNGDEFTTARKFLTDSTRSDWDPAAQVVIYDGSVPLSYDDSVEGTVEVEVTVVATVDSDGIYTQAAPGTSSTMTYTVVQDASGEWRISGLPDGVLMSEVNFGTLYRKTAVYFLSADGSTLVPDLRWYPLRNRATYAVRGLLAGAAEWLSPAVISAIPDGTELSIDSVTVSGGTANVPLTSAVQTASADDRALLVAQLEQTLTALPQVQGVEVTVGDVPLEVSAATPDLAVDPGVGRTLTVLNDENQLATYNGAELTPVPDAVDLGSLDPADPAVGYSSDQQTVLLAGRLAAAHRGQCRGRGHGAVGGTEPAAALVRSGRVDLDRGAAELWRAPHRPRRREPGGDRDADARRDEHPRPPGEQGRRTAGDDRRLGRVGAGDGARDHHRRRRNSHRDRTRRAGWAASSATPATWSGWTRPS
>NZ_CP042828.1|WP_168211801.1|3427533_3427773_-|hypothetical-protein
MDETQLGVLGVSQATQTVHVVEVGGRTTPLPSVADTVRIASGRGVRDLYLATEDGGLYGRSGNGWAPVISGVRFPTFPG
>NZ_CP042828.1|WP_168211800.1|3426340_3427327_-|hypothetical-protein
MHSLLDDLPVRPDGLILVADASAVGSRYRVHRLHQAGTLTRVWPGVYAVTETEEQRGPRADAARYLRRVRAAAHQMPGRVFTSYSAAALLGLPIVGRWPRAVYVLAGGPNGSRRGDVRYIGHRLDAPEVRVDGIRLTAPAYTVIQVARNATLAAGLVAADAALRHPPYAERAPLLTPEVLSGEHERLRPYRGHARAAAVLCRATPFADGALESISRLVIEELGFAAPELQHRFWLPDLGEYAWVDFCWPELGIAMEADGHGKYLDAGSGTRAAQRVVREKRREDEIRAQVEKFGRWDWDDAWRVHPLERKLERAGVPRTRPRRRLFVP
>NZ_CP042828.1|WP_168211799.1|3425403_3426207_-|ComF-family-protein
MRLQTVVRSAVALSEDVVGLMLPVACAGCGRGERSLCAACAALFGAPYRCEEDTVVLGAQDYAPALGLPTWTTAAYAGPARHVVLAWKSGARPDLSRVLAEVGERAGRRLASELVLPAGSATFAGSGTASGAKGADLLVVPAPSGWRRRTARLLVAADLAAALAGGLAAGTGARVWAVDVLRRRGGSGHRLGAAARTRRGRGSARVVTAVPTGVPVLIVDDVVTTGSTIHASRTALAGAGAEVIGAFALAATPRPGRPVVVPGGPAT
>NZ_CP042828.1|WP_147917956.1|3424412_3425096_-|ribosome-associated-translation-inhibitor-RaiA
MEIVLVSRHTESPERFRRHVEEKLAKVPQLSPYAQRVDVEVTHENNPRLADRSERVELTVRAKGPVVRAEASASDRYAALDLATAKLLERLRRARDRRKTHHRRRSVQPPTPEELGIVGEQPAAEEEVPETPQPPTEPGVAVEAQLGDSPVVIRQKVHETEPMTVDQALAEMELVGHPFYLFIDAETQHPCVVYNRRGWTYGVIRLNYTATSNGSEAAEETIHSASA
>NZ_CP042828.1|WP_147919546.1|3435653_3436628_+|AAA-domain-containing-protein
MPAEAPASDSPVRATLAAVRGEVAKAVVGQDAAVTGLVIALLCRGHVLLEGVPGVAKTLLTRTLGAALELEMKRVQFTPDLMPGDVTGSLIYDARTAEFSFREGPVFTNLMLADEINRTPPKTQASLLEAMEERQVSVDGEPRPLPDPFMVIATQNPVEYEGTYPLPEAQLDRFLLKLILPLPQRGEEIEVLHRHAHDFNPRDLAAAGVRAVADAEQLAAARAEVAEVEIGPEVLGYIVDICRATRTSPSLQLGVSPRGATALLGTSRAWAWLSGRRFVTPDDVKALAHPTLRHRVQLRAEAELEGVTAETVLDGILGSVPVPR
>NZ_CP042828.1|WP_147917964.1|3436627_3437920_+|DUF58-domain-containing-protein
MVITGPAVALVALGILPVALVPQAATVWVWALIVVLAVAADLLLAGSPAAVQVRRGSLGSVRREQPVTSVLTLTNTSNRTLRVLVRDAWQPTAGAGTNRFRLTVPPGESRRVRTPLRPHRRGDLQADLVTVRCYGPLRLAARQASRNVPGSLRVLSEFKSRRHLPSRLARLREMDGRTAVNVRGQGTEFDSLREYVIGDDVRAIDWRATARRSEVVVRTWRPERDRRVMIVLDSSRLSAARLGDEPRIEAQIEAALLLTALASKAGDRVDLLALDHTVRARVRGNHGPTVMAKLADALSVVHPTLVEPDWTRTTQQVRDTLSQRALVVLLTAVEAGVAETGLLPAVATLARDHQLIVASATDPGTDQLRRSRETSAEVFDAAAAERSDLERAALAARLRRTGAEVVERLPDHLPPALADTYLALKAAGRL
>NZ_CP042828.1|WP_147917965.1|3438108_3439626_-|serine-hydrolase
MSQTDVSAVLRSSDSAETVGIPSSAILALLRRMERRGLNAHSLLIARHGAIAFEAYWHPYSPETPHRLYSASKSLVSLAIGTLVDDGRLSLEDRIIDHFPDKLPSGDLDPYLTAMRVVDLLTMRTAHGSTTFKQVADTDWVRTFFTVPPNRQPGMVFSYDTSGSVVLTALVERLSGKPLTEYLTDRVLTRIGVQDPWFSLVSPTGMDLAERGGQPTWREVESNPEGTSHGGSGVFCTPRDLLRVAQLCLAQGRWGSDQVISAEFLRAATDYQVSTALTSPAFPDGRCGYGYQFWRNRGGGYSMRGMGGQIALCLPEEDVVIVTTGDNQGVGGADQAFFDAVAEELVPALGAPRAVDPDSAAELARYARSLALAPVPVTGSRAGGRFRAEYELDPGPTAFVGLELDVSPDFGVLRLHTADGQQREFRFGLGSLVRHGLPGYGYETHSSGAWLDENTLHVHSHVLGRYLAQIDLMVTAGGEAVTLVMNRAAEAFAEEYEGTVSGRRR
>NZ_CP042828.1|WP_147919547.1|3440928_3441684_+|RDD-family-protein
MLLSRVGSGIIDLATYGLAGLILVLLGLRLVSNDAQMSVLMVVAMASAMLILPTTVETLTRGVSAGKFITGIRMVRDDGGPVRFRQAFVRALVGTVEIWATFGAAAVITSLVNARGKRLGDLLAGTYAARIRGSEMPLQPLLMPPDLGSWAESADIRRLPDALAVQARVFLSRTGTLQPQSRVRAAYTLAAAVEPYVAPPPPWGANPERFLAAVLVARRDREYGSSLRRQEQEAHQAERMRELPFGVTDYS
>NZ_CP042828.1|WP_147917966.1|3441830_3443144_-|Na+/H+-antiporter-NhaA
MSEKKDAAPNADAGGSGGREPLFSRLTPGGERNFLDTLRGETIGGVLLIVGAVVALIWANSPWQDSYAAVRDTRLGIDALGLDLSIGEWAADGLLAVFFFVVGVELKREVVTGELRRMSTAIVPVAAAAGGMAAPALIYLAFNLTMADGAPDGWAIPTATDIAFAVTVLALVGKWLPTALRAFLLTLAVVDDLLAIIIIAVVYSDSLALLWLLAVVACVAVFSMLVRKGITAWYVLLPLGILTWYFMHASGVHATIAGVALGMATPALPLKGKAASRAPARAAEQSPAAYFEHVWRPASAGFVVPVFALFTAGVMVDPSVIGATLRDPVAIGVALGLVVGKPLGILAATWLITRTRHATLARGLGWLDIGAMGVLAGIGFTVSLLVAELAFGVGHPRDEHAKIAVLSASVFAALVGSALLWWRGRVHRARGTVTASE
>NZ_CP042828.1|WP_147917967.1|3443154_3444633_-|adenosylhomocysteinase
MTFSEASGRYKVRDLSLAEAGRHQIRLAEHEMPGLMALRAEYGDAQPLRGARIAGSLHMTVQTAVLIETLTALGAQVRWASCNIFSTQDEAAAAVAVGPHGTPEDPRGVPVFAWKGESLAEYWDCTEQILLWPDGGPNLILDDGGDATMLVHEGRRLEAAGAVGPAPQPGDADYSEEKVVFLDVIRRSLASDPQRWHTVAAGIRGVSEETTTGVHRLYQLAAAGELLFPAINVNDSVTKSKFDNRYGIRHSLPDGINRATDILIGGKVAVVCGYGDVGKGAAESLRGQGARVVVTEIDPICALQAAMDGYQVAQLESVLAEGDFFITTTGNVNVITTEHLAGMKDKAVVGNVGHFDNEIDVAGLARSGVQRTEIKPQVHEWTFPATAERDEHSIIVLSEGRLLNLGNATGHPSFVMSNSFANQVIAQMELYAPDAEETYDLDVHRLPKVLDEKVARLHLEALGVELTELTKEQAEYIDVDVAGPYKSEHYRY
>NZ_CP042828.1|WP_147917968.1|3444887_3445823_-|glycine-betaine-ABC-transporter-substrate-binding-protein
MKTPQKTLRRRQVTALFASGAIGLSLAACGSDDGGSDSGDGGEGGGDNTITLGYLPSWTDGLSTAYLLDHFLTEAGYTVEHEELSEAGILYTALAQNDVDLYPSAWPEVTHASYMEEYGDDIEDLATYYEGAVLTFAVPEYSDITSIDQLPDHVDELGGRVVGIEPSAGLTGVTEDDVFPTYGLGDAGFTLETSSTATMITELESAIDAEEPIVVTLWRPFWANDAYPVRDLEDPEGALGESEGLHFLANIDFSGEFPEVAEWIGQIALDDEQYAGMESAVVNDNPDDPAAGIEQFLEEYPDAIPELPAAE
>NZ_CP042828.1|WP_147917969.1|3445860_3446820_-|ABC-transporter-permease-subunit
MSESPLPHPPLGEFADKAVDWIKQTMPELLQGIQDTFNTASETLTDVLMFLPALVMAVVFALLAFVVRSWKFAIFVVIGMGLIISMELWLLAMQTLAMVLVATLVAVIIAIPVGILAAKSRTVSAIVRPICDFLQTMPALVYLVPVVIFFSIGYAPGVVATIIFAMAPGIRLTELGIRQVDSETVEAGQAFGGTGGQILRGIQLPLGLPTIMAGVNQVIMLGLSMAVMAGFVGAPGLGKEVVAALGTVDVAKGFEAGLGIVILAIFLDRTTGAVGQENKGSLATMLRGRRKAAAKKAKAQATAPETDSEETEKALQGAH
>NZ_CP042828.1|WP_147917970.1|3446816_3448088_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MPAIEATGLTKIFGRRPQRGVKMLREGVDRAQLRKEGLTAAVIDASFDVEPGEIFVVMGLSGSGKSTLIRTVNGLLEPTAGTLQVAGEEITTLSTKGLRALRRNKVSMVFQHFALLPHRTVGENAAYALELRGVNRAEREKAGDEALGMVGLGGWGGYLPSELSGGMRQRVGLARALAAGTDIMLMDEAFSALDPLIRKEMQDQLLDLQGKLDKTILFITHDLNEAMRLGNRIAMMRDGRIVQIGTAEEILNEPATEYVSQFVADVDRTRVLTASAVMERPVAVVGPGNGPRAAHRLMGEHQTRSLLVVSNDRHVRGIVWEEDIAEAVRSGKDTLPIKHDGVAQVAEDTPLADLFPYAAATHAPLAVVNDKDVLVGLIPRVTLLSALTLGDDEVELEPVGLPSSNGHSDPDDKVPALSEGGAR
>NZ_CP042828.1|WP_147917971.1|3448372_3449539_+|nucleotide-sugar-dehydrogenase
MKIAVAGCGYVGLSIATLLAQHHEVVALDVDQDKVDAVNAGHSPIVDPELSEYLASGRLNLRATVDGADAYQGAAYVVVATPTDYDPKNNYFNTSTVETVVAEVERTNPSAVLVIKSTIPVGFTEQMRTEHPGLQVLFSPEFLREGKALWDNLHPSRIVVGDRSSAGQEFADLLMQGSLESEVPVLLTDATEAEAIKLFANTYLALRVAYFNELDTFAVTRGLDSAQIIQGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYQQVPQNLVRAVVDSNTTRKDFIAADVLARQPQVVGVFGLAMKSGSDNFRASSIQGIMKRIKAKGVEVIVYEPALDAEDFFRSEVVRDLAEFKRRADVIITNRRDDALADVAQKVYTRDVYGRD

Crispr_ID: NZ_CP042828_14

• CRISPR_ID: NZ_CP042828_14
• CRISPR_location: 3550849-3550949
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_14

Consensus_repeat	Method
CCGGTCGCGTGCACCTCGCCGCC	CRISPRCasFinder

spacers of NZ_CP042828_14

>14.1|3550872|55|NZ_CP042828|CRISPRCasFinder
GTTGATGGTGATCTCGCCACTGCCGGTGTCCAGTCCGCCACCGATCCCGGTTCCC

CRISPR arrays and Neighbor proteins around NZ_CP042828_14

CRISPR arrays

The CRISPR arrays of NZ_CP042828_14

>merge|NZ_CP042828|14|3550849-3550949|CRISPRCasFinder
CCGGTCGCGTGCACCTCGCCGCCGTTGATGGTGATCTCGCCACTGCCGGTGTCCAGTCCGCCACCGATCCCGGTTCCCCCGGTAGCGTGCACCTCGCCGCC

>NZ_CP042828|14|13|3550849-3550949|CRISPRCasFinder
CCGGTCGCGTGCACCTCGCCGCC	GTTGATGGTGATCTCGCCACTGCCGGTGTCCAGTCCGCCACCGATCCCGGTTCCC
CCGGTAGCGTGCACCTCGCCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_147918043.1|3555334_3556429_-|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NZ_CP042828.1|WP_147918047.1|3560716_3561505_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147918042.1|3554558_3555242_-|response-regulator	unknown	unknown	gnl|CDD|223816
NZ_CP042828.1|WP_147918041.1|3552776_3553307_+|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NZ_CP042828.1|WP_147918034.1|3539133_3540162_-|DUF4339-domain-containing-protein	unknown	unknown	gnl|CDD|376704
NZ_CP042828.1|WP_147919557.1|3545962_3546793_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224096
NZ_CP042828.1|WP_147918039.1|3544463_3545753_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270303
NZ_CP042828.1|WP_147919558.1|3546882_3547659_+|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223472
NZ_CP042828.1|WP_147918037.1|3542168_3543416_-|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl|CDD|235674
NZ_CP042828.1|WP_147919559.1|3547673_3548687_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176219
NZ_CP042828.1|WP_147918045.1|3557800_3558709_-|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl|CDD|223417
NZ_CP042828.1|WP_147918048.1|3561669_3562464_-|hypothetical-protein	unknown	unknown	gnl|CDD|235095
NZ_CP042828.1|WP_147919560.1|3553218_3554112_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP042828.1|WP_147919556.1|3540742_3541624_+|carbohydrate-kinase	unknown	unknown	gnl|CDD|238920
NZ_CP042828.1|WP_147918035.1|3540266_3540728_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_168211946.1|3558824_3560450_+|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP042828.1|WP_147918044.1|3557185_3557734_+|DJ-1/PfpI/YhbO-family-deglycase/protease	unknown	unknown	gnl|CDD|153228
NZ_CP042828.1|WP_147918046.1|3560446_3560695_+|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl|CDD|379386
NZ_CP042828.1|WP_147918036.1|3541644_3542172_-|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl|CDD|376377
NZ_CP042828.1|WP_147918038.1|3543544_3544333_-|FCD-domain-containing-protein	unknown	unknown	gnl|CDD|225097

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_147918043.1|3555334_3556429_-|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	2.6457e-25
NZ_CP042828.1|WP_147918042.1|3554558_3555242_-|response-regulator	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.00273e-80
NZ_CP042828.1|WP_147918041.1|3552776_3553307_+|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	1.39035e-25
NZ_CP042828.1|WP_147918034.1|3539133_3540162_-|DUF4339-domain-containing-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.08031e-82
NZ_CP042828.1|WP_147919557.1|3545962_3546793_+|ABC-transporter-permease-subunit	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.62237e-71
NZ_CP042828.1|WP_147918039.1|3544463_3545753_+|extracellular-solute-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.5775e-67
NZ_CP042828.1|WP_147919558.1|3546882_3547659_+|ABC-transporter-permease-subunit	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.58521e-66
NZ_CP042828.1|WP_147918037.1|3542168_3543416_-|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl|CDD|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	3.41673e-157
NZ_CP042828.1|WP_147919559.1|3547673_3548687_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176219	cd08258, Zn_ADH4, Alcohol dehydrogenases of the MDR family. This group shares the zinc coordination sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of an beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.92629e-92
NZ_CP042828.1|WP_147918045.1|3557800_3558709_-|biotin--[acetyl-CoA-carboxylase]-ligase	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	4.56653e-37
NZ_CP042828.1|WP_147918048.1|3561669_3562464_-|hypothetical-protein	gnl|CDD|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	0.00334762
NZ_CP042828.1|WP_147919556.1|3540742_3541624_+|carbohydrate-kinase	gnl|CDD|238920	cd01945, ribokinase_group_B, Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .	1.34908e-33
NZ_CP042828.1|WP_147919560.1|3553218_3554112_-|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.32658e-36
NZ_CP042828.1|WP_168211946.1|3558824_3560450_+|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP042828.1|WP_147918044.1|3557185_3557734_+|DJ-1/PfpI/YhbO-family-deglycase/protease	gnl|CDD|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	3.67639e-78
NZ_CP042828.1|WP_147918046.1|3560446_3560695_+|acyl-CoA-carboxylase-subunit-epsilon	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	2.50973e-08
NZ_CP042828.1|WP_147918036.1|3541644_3542172_-|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl|CDD|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	5.90022e-81
NZ_CP042828.1|WP_147918038.1|3543544_3544333_-|FCD-domain-containing-protein	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	1.01345e-36

Protein sequences

>NZ_CP042828.1|WP_147919559.1|3547673_3548687_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MPAVVKHGPGEAGVALREVPVPVPRTGQVLLRVVAAGVCGTDLHIARDEYRHEAPVVMGHELLAEVEDVGGEVSTEWVGARVVCETYFSTCGSCPLCRAGRPNLCPSRRSIGSFADGGFAPRLALPVGNLHRIEQGGIGAVLAEPLACAAQCLCDPAVVNPGDEVLVLGPGAMGQLSAQIARAQGGTVTLAGLPEDAHRLQIAAGLGLQTLASTPPAESFDVVIEATGSGGGARAALAAARRGGRYVQVGIIGQETPLNLDAVLYKELTLTSGFASTPQSWRRALALISAGQVRLEPLVTSRYPLSQWSAAFQAVRTGEGVKTILEPEASPAPGVLA
>NZ_CP042828.1|WP_147919558.1|3546882_3547659_+|ABC-transporter-permease-subunit
MIIFVVLVFVVPLLWMVMASFKTNVDIQDTTKTFAFTPILDNYANVLRNDSYLSFVRNSFVVAAGATGISLLLGVPAAYSMSRFNMQKSALMVLLARIIPGVSLLVPWYYVFANLGLVGGYSVLIISHMFILIPISVYIMMSFFDSMPRELEDAALVDGLTPIGAFLRILLRLSAPGVATAAILSFIFSWNNFMFALVLSGANTKTLPVAVFDFVSYASIDWGAIMAATCIMTLPIIVVALLAQKYIVSGLTAGATKG
>NZ_CP042828.1|WP_147919557.1|3545962_3546793_+|ABC-transporter-permease-subunit
MVFTFLLICIPIGWTLYLSLTDAKGSVRRPADFIGIENYVEVLTDTDRFWPAVGRTGLFTFGALALELILGMAIALLLWRSFRGQRWVRVSILLPFVATPVAIAMMWRLIFEPNIGFANRVLSWVGLPAQPWLADPGMTLPTLIFIDVWEFTPMVAIILLAGLSTLPDDPDEAARIDGAGVWQRFWYITLPLLKPVVLVAVLLRAIDALKTFDLLYVTKGQGGGSFHEAETLNIYVYGLSFKYNDFGVASAVLILFFLMILAVMWILTFRRKGAKL
>NZ_CP042828.1|WP_147918039.1|3544463_3545753_+|extracellular-solute-binding-protein
MQHRQAVRVAVITTAAALSMGTLAACSGDGDGESTTLNVTLANHVWTDIITEKIPEFEEQSGLDVVVTQLSEDQLVDNYKVKLNAGSTDVDVMMYRPLQVGKLFGQSGYFADITEQVNGAEDWNWDDFQAGPVGLTTYEDQIVGVPMITESEMLYYRTDLLEEAGLEVPTTMAELEEAARTIKEENEGTAGIVMRSQASAAVTQFSGFLYSFGGTWIDDDGNSAIDSPEAQEAYAYYGGLLHDYGPDQISTDMSWPEAAAIFAQGDAGFWIDASSLYENVYNPENSQVGDQVGFAPFPEGPAGSQPYNVAAWALGINSASENQENAWEFIQWATSPEMTLDIQTEGVPSARTSVWEDPEGTASFPEDLAAAIATNGENGVGQDRPLVVGVAEAREIVGAPIVAAITGEDAAAAATQANEQFQALLESEE
>NZ_CP042828.1|WP_147918038.1|3543544_3544333_-|FCD-domain-containing-protein
MTDDAAAVLVTGTGRTRLATRRRGLYDRVVDVIGEQIVNGAIPVGTTLFVDQICAELDISRSVVREGVRTLSSMGLVESRPQRGTRVLPRQEWDLLHPRVVHWRGEGPDYLQQMYELLELRLGIEHAAAHFAAERMGAEERTAVVAAGQAMEKAYAEHDPHRFFDADAQLHRLILEGSGNALISQFSDTVMTSLNIRGTAASRSYSTAQSLDSESARRHRELAEAVAAGEPEVAQRASAEIMFATRAEVSALLARRKRPGQQ
>NZ_CP042828.1|WP_147918037.1|3542168_3543416_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MGPVVAVVGGGQLARMMAEPAGALQIQLRALVEADDGAAAQVIPASTVGRSDDAEAIAALTEGADVLTFEHEHVPQQILTALVDAGVNVQPGPAALRHAQDKIVMRERMSQLGAPCPRWAAVRTEEDLVTEAARLGWPVVAKTPVGGYDGKGVAVLAGPGDAAEVADWFSHPRGEVLLEEKVDFTRELAVLVARRPSGEMRTWPVVETVQAGGVCAEVLAPAPGLPAHVAEDATDVARSIAEGLDVTGVLAVEMFEARDGILLVNELAMRPHNSGHVTIDAAVTSQFEQHLRAVLDLPLGSTDLTAEVAAMVNVLGSELDDPAIAYPELMADYPDAKVHLYGKGVRPGRKLGHVTVTGTDPAEVRRRAQEAARLLEGRSGRKGTDMSARSPHGGTARDELCRSEAPQRSGRKGTG
>NZ_CP042828.1|WP_147918036.1|3541644_3542172_-|5-(carboxyamino)imidazole-ribonucleotide-mutase
MTAAVGVVMGSDSDWPVMSAAADVLAEFEIETEVDVVSAHRMPEEMIRYGQEADERGLRVIIAGAGGAAHLPGMLAAVTPLPVIGVPVPLAHLDGMDSLLSIVQMPAGVPVATVSVGGAKNAGLLAARILAAGADEQAAALRARMRTFQADLRTAAQEKGARLRAQRSHRTGFNA
>NZ_CP042828.1|WP_147919556.1|3540742_3541624_+|carbohydrate-kinase
MAWFIGLTTLDVVHRASAPPSANEKVTASRQDVAAGGPAANAAVVARALGIGAHLISALGGSPMAAAARADLEAAGVQVVDIAPEHELAVSAILVDEGTGARSVTSTDGGAADPAPPDFSGSPDPAVVLIDGHYPRLAVAAARAARERGALVVLDAGRWRPVFAELIGLADLVAASADFALPDGGRGPGALVAAGAGAGVVTAGSGPVRYATGTEHGEIAVPAVPVADTLAAGDAFHGGLVAGLVTRRLRAPGPGASLPAAPLRRALDYAVAVASHRVQHVGPRSYLETLPRR
>NZ_CP042828.1|WP_147918035.1|3540266_3540728_+|hypothetical-protein
MTAHRTGLMPPGRRARVLIALLAFLLPVAAVTGCSQVREQAGSVVEHAIEEAIEGLDLTDGLPPDFPVDDVPLVEGSVRGASQTDADGQATWVVLVEAEDAGESARQALLDAGFEITHTVTTDAGVLAELAGHGFAVKLIASTSRVVYVVTSS
>NZ_CP042828.1|WP_147918034.1|3539133_3540162_-|DUF4339-domain-containing-protein
MAQWFFSYNGERSGPFDDADARAQAARKPDGHAWQEGFSEWLPIRSVPELDADAGAPPPPPPPLGRARAADDIEFTIHGEDMQFVEIELDPGETAIAEAGALMVKDASVRMDTVFGDGSTPGGGAGPGGGGGGIMDKLMSAGKRVLTGESLFTTMFTHEGSGKAHVSFAAPFPGTVLPMRLADHGGRLICQKDSFLAGARGVSIGIHFQRKILTGLFGGEGFIMQKLEGDGWVFVHAGGTVIERELAPGERIDVDTGCVVAYHDTVDMDVEAVGGVKSMFFGGEGVFLAKLTGPGKVWLQSLPFSRMAGRMLAAAPQAGGQDRGEGSVLGGLGSILGGDRSF
>NZ_CP042828.1|WP_147918041.1|3552776_3553307_+|GtrA-family-protein
MTFTDRARRLRAWLGELARFGTVGLLAFVVDIGLMNLLRFGPGELLGPKPLTAKVISVSVAMLVAWLGNRYWTFAAKRSAPTAAARSRELVQFVAVNLVGMAIGVGCLAISHYLLGFTSPLADNISANGVGLVLGTAFRYLAYRYWVFTGDGADAPPPPEPPVAAPSSDRDASELR
>NZ_CP042828.1|WP_147919560.1|3553218_3554112_-|HAMP-domain-containing-protein
MVALWSARRLAAPLIYLAATAEQIGSGQVRPRLESSGVEEIDLVGAELVRTSDRLAGRIAAERQFAANVSHQLRTPLTALSMRLEEIQLLSEDEDVREEARISLEQVERLVHVVDDLLKASRKADGGTTEALRLEEVFAQQADEWSQTYLRDGRSLEFDAGDDEAVFATPGALAQTLATLIENSLKYGEGTTSVRVRESKSGSDTGVVIEVADEGPGVSDDLAPRIFERHVTAGRGSGLGLALARDLVTADGGRLELAQRRPPVFAIFLSAVPKRLDPNSVLPPGALVVVGRRRRRR
>NZ_CP042828.1|WP_147918042.1|3554558_3555242_-|response-regulator
MTRVLLAEDDPAIAEPLARALTREGYDVSVHGTGRGAIDDAAQADLFVLDLGLPDMDGLDVARWIRNQGLTTPILVLTARADEVDLVVGLDAGADDYVTKPFRLAELLARVRALLRRAGAEGEESDEISAQDVRVDVAAHRAFQASRELQLTAKEFDLLRVLVREAGSVVSRDALMREVWASDPTGSTKTLDMHVSWLRRKLGDDANAPRYISTVRGMGFRFENGVS
>NZ_CP042828.1|WP_147918043.1|3555334_3556429_-|adenylate/guanylate-cyclase-domain-containing-protein
MNAPPGTAPPPTDGERPHAAHAAPSGDEGRTTVNRHHERLLGGPPELTAAEFASRAGVEESIARQYWRSLGFPDVPGDEQWFTDTDVAALRALAEAVESDTVSLNAAQDLVRGLGHSMDRLVLWQVEAMVQDLSARYRLDDVSARLVVLDRMVELSPLLREQLDYAWRRQLIALLGRIDRDIARLGSEVGEPDQLPLERAIGFIDIVSYTTRSADLTPKALATLVQDFESAARDVVARYGGRVVKTIGDAVLFVADDLPAGARVATSLVQVMAAQNLPVRGAVVWGRLLSRSGDVFGPVVNLASRLTDLADPFTILMDDVSAAVLESLPAGQEFQMVHSAPAQVQGLGEVRPVQVQRQRSTTTD
>NZ_CP042828.1|WP_147918044.1|3557185_3557734_+|DJ-1/PfpI/YhbO-family-deglycase/protease
MADLTGTTVAFLLTDHYEDSELTSPWEAATNAGATAVLVSPAKGTVSGKKGHSQSVDLRVEEANAANFDALMLPGGTGNADALRMNADAVAFTRDFFAQHKPVGVICHGAWILTDAGVLAGRTLTSFPSLQTDLRNAGAAWVDEEVVVDQGLVSSRTPDDLPAFNAKFVEELGEGKHSGQTT
>NZ_CP042828.1|WP_147918045.1|3557800_3558709_-|biotin--[acetyl-CoA-carboxylase]-ligase
MGMGPEDRPEPRLEIVEATGSTNADLARVAGSDPGAWPHLSALLARRQLAGRGRSGRTWTTDEHAALTFSILLRPEEPRERWGWIPLLGGAAVVQALRAAMPAADAGTDLAGESRLSQASADGAGHLSRDSTTAAGSVGAVTREVAVGLKWPNDVVHLGGTEVLQDWGCLRKVGGLLAEVLPDGRSLVLGIGINLVGDRLPVPWAGTAADLGVRTDPTRLAGAIRGKLSATLADWAAGTDPRELVAPMCLTLGTAVRVGRPDGSALEGEAVDLAEDGALVVRLDDGTDRVVRAGDVTHLRPA
>NZ_CP042828.1|WP_168211946.1|3558824_3560450_+|acyl-CoA-carboxylase-subunit-beta
MAGGHNYSAYVTSEIHPDTSTTAGKLADLAGRTETGPQALAATATEKQGARGKLSARDRIDQLLDEGSFTELDAFATHRSVNFGLDAKHIPGDGVVVGYGTIDGRQVCVYSQDFTVFGGSLGEVHGQKITKVMDLALRTGVPLIGISDGGGARIQEGVAALTQFAEIFRRNVAASGVIPQISLILGPSAGGAVYSPALTDFIVMADQTSNMFITGPDVIRAVTGEDVGFEELGGGRTHNERSGVAHYLAADEEDAFDYVKALLHYLPSNNLSDPETYPEEAELEITDADATLDELVPDSDNQPYDMHAVIEQVLDDDEFLEVQPLYAPNVIVGFGHVEGHPVGVVANQPQQMAGTLDIAASEKAARFVRTCDAFNIPVLTFVDVPGFLPGTDQEWNGIIRRGAKLIFAYAEATVPLITVITRKAYGGAYIVMASKQLGADLNLAWPTAQIAVMGSGGAVNILQRRTLKKVAEDGGDVEAERARLVAEYEEAIVNPWDAAQRGYVDAVIRPAETRVQIVKGLRALRTKRASLPAKKHGNIPL
>NZ_CP042828.1|WP_147918046.1|3560446_3560695_+|acyl-CoA-carboxylase-subunit-epsilon
MSAPSHFSGQGEVPAGLVRVLRGAPDEAELAALVAGIVAARADDGAAESEEDLTSVWGDHGRRLGLAARPGGAAWRWSARAY
>NZ_CP042828.1|WP_147918047.1|3560716_3561505_-|hypothetical-protein
MNDLIAVDGTEAFHQFAASVEDPTKMLDYAPVVGDCYDAAKAFGEGDWAGGLQAAASAGTAIAAAVSDPLGTLMSSCAAFLLDYMPPLPQMLDVLAGNPALVMSIGETWVNVSRALTERAAALEAAMSQMLAKWRGAAADAYRARMEFLIGLTTGLSSAAMGIGCGFAVASTVVEFVRTIVRDLIADLVGRLISYVIETGATLGAALPVVIGQASIAIADTATSALKWTGTLTDAIKKAIAILEKLKAAIEAVDEAITEVTA
>NZ_CP042828.1|WP_147918048.1|3561669_3562464_-|hypothetical-protein
MRARRRAFLIVLLGWVGLFVVVTIAFARARGSFQRIADDPPIVLAIIGVVLVVVIVVASLARRGGQQRVHAATGQQRTAWAHSVGWSYHPRPREIPPDALSEVETSQRADPIRITDEATGQHRGRRAFVHSRDTWVRVMSRLDTSRREVVGVEARIELPRTVVLTRMNAAGARTVRVQPAVGLSRVPQPFGTSTALFTPAGLEAVIATALRPALEVRHEDWLKIVCVGRWVLISADRDASTAAALRRLDLADHVAGLLEAGATG

Crispr_ID: NZ_CP042828_15

• CRISPR_ID: NZ_CP042828_15
• CRISPR_location: 4364026-4364140
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP042828_15

Consensus_repeat	Method
CCCGGGCGATTCGGCAGCCAGCCCGC	CRISPRCasFinder

spacers of NZ_CP042828_15

>15.1|4364052|63|NZ_CP042828|CRISPRCasFinder
AGTCCCATCCCGGGCGATTCGGCAGCCAGCCCGCCCGCAGTCCCACCCAGCCCGCAGGCCCAC

CRISPR arrays and Neighbor proteins around NZ_CP042828_15

CRISPR arrays

The CRISPR arrays of NZ_CP042828_15

>merge|NZ_CP042828|15|4364026-4364140|CRISPRCasFinder
CCCGCCCGCAGCTCCACCCAGCCCGCAGTCCCATCCCGGGCGATTCGGCAGCCAGCCCGCCCGCAGTCCCACCCAGCCCGCAGGCCCACCCGAGGCGATTCGGCAGCCAGCCCGC

>NZ_CP042828|15|14|4364026-4364140|CRISPRCasFinder
CCCGCCCGCAGCTCCACCCAGCCCGC	AGTCCCATCCCGGGCGATTCGGCAGCCAGCCCGCCCGCAGTCCCACCCAGCCCGCAGGCCCAC
CCGAGGCGATTCGGCAGCCAGCCCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042828.1|WP_168211875.1|4371644_4371809_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147919638.1|4357136_4358618_+|DUF4038-domain-containing-protein	unknown	unknown	gnl|CDD|379072
NZ_CP042828.1|WP_147918668.1|4354766_4355162_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_168211876.1|4371874_4373068_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270298
NZ_CP042828.1|WP_147918675.1|4365866_4367432_+|family-43-glycosylhydrolase	unknown	unknown	gnl|CDD|350115
NZ_CP042828.1|WP_147918669.1|4355195_4355990_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176106
NZ_CP042828.1|WP_147918670.1|4355986_4356907_+|A/G-specific-adenine-glycosylase	unknown	unknown	gnl|CDD|224115
NZ_CP042828.1|WP_147918679.1|4371181_4371661_-|DUF4064-domain-containing-protein	unknown	unknown	gnl|CDD|372544
NZ_CP042828.1|WP_147918678.1|4370267_4371182_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223472
NZ_CP042828.1|WP_147918677.1|4369333_4370266_+|AEC-family-transporter	unknown	unknown	gnl|CDD|223751
NZ_CP042828.1|WP_168211874.1|4360156_4361317_-|transcriptional-regulator	unknown	unknown	gnl|CDD|225263
NZ_CP042828.1|WP_168211877.1|4373088_4373283_-|hypothetical-protein	unknown	unknown	gnl|CDD|270298
NZ_CP042828.1|WP_147919639.1|4359627_4360125_-|amino-acid-N-acetyltransferase	unknown	unknown	gnl|CDD|236132
NZ_CP042828.1|WP_147918671.1|4358727_4359303_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP042828.1|WP_147918673.1|4363034_4363961_+|NAD-binding-protein	unknown	unknown	gnl|CDD|224995
NZ_CP042828.1|WP_147918667.1|4353710_4354697_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_CP042828.1|WP_147918676.1|4367431_4369321_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224525
NZ_CP042828.1|WP_147918672.1|4361315_4362833_+|glycerol-kinase-GlpK	unknown	unknown	gnl|CDD|198362
NZ_CP042828.1|WP_147918680.1|4373388_4374177_-|DUF624-domain-containing-protein	unknown	unknown	gnl|CDD|227865
NZ_CP042828.1|WP_147918674.1|4364428_4365811_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP042828.1|WP_168211877.1|4373088_4373283_-|hypothetical-protein	gnl|CDD|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	7.6451e-12
NZ_CP042828.1|WP_147919638.1|4357136_4358618_+|DUF4038-domain-containing-protein	gnl|CDD|379072	pfam13204, DUF4038, Protein of unknown function (DUF4038). A family of putative cellulases.	1.58266e-135
NZ_CP042828.1|WP_168211876.1|4371874_4373068_-|extracellular-solute-binding-protein	gnl|CDD|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	7.4491e-88
NZ_CP042828.1|WP_147918675.1|4365866_4367432_+|family-43-glycosylhydrolase	gnl|CDD|350115	cd09001, GH43_FsAxh1-like, Glycosyl hydrolase family 43 such as Fibrobacter succinogenes subsp. succinogenes S85 arabinoxylan alpha-L-arabinofuranosidase. This glycosyl hydrolase family 43 (GH43) includes mostly enzymes that have been annotated as having beta-1,4-xylosidase (beta-D-xylosidase; xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. This subfamily includes the characterized Clostridium stercorarium F-9 beta-xylosidase Xyl43B. It also includes Humicola insolens AXHd3 (HiAXHd3), a GH43 arabinofuranosidase (EC 3.2.1.55) that hydrolyzes O3-linked arabinose of doubly substituted xylans, a feature of the polysaccharide that is recalcitrant to degradation. It possesses an additional C-terminal beta-sandwich domain such that the interface between the domains comprises a xylan binding cleft that houses the active site pocket. The HiAXHd3 active site is tuned to hydrolyze arabinofuranosyl or xylosyl linkages, and the topology of the distal regions of the substrate binding surface confers specificity. It also includes Fibrobacter succinogenes subsp. succinogenes S85 arabinoxylan alpha-L-arabinofuranosidase (Axh1;Fisuc_1769;FSU_2269), Paenibacillus sp. E18 alpha-L-arabinofuranosidase (Abf43A), Bifidobacterium adolescentis ATCC 15703 double substituted xylan alpha-1,3-L-specific arabinofuranosidase d3 (AXHd3;AXH-d3;BaAXH-d3;BAD_0301;E-AFAM2), and Chrysosporium lucknowense C1 arabinoxylan hydrolase / double substituted xylan alpha-1,3-L-arabinofuranosidase (Abn7;AXHd). A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	3.3976e-118
NZ_CP042828.1|WP_147918669.1|4355195_4355990_+|LysR-family-transcriptional-regulator	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	3.01555e-16
NZ_CP042828.1|WP_147918670.1|4355986_4356907_+|A/G-specific-adenine-glycosylase	gnl|CDD|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	2.0097e-89
NZ_CP042828.1|WP_147918679.1|4371181_4371661_-|DUF4064-domain-containing-protein	gnl|CDD|372544	pfam13273, DUF4064, Protein of unknown function (DUF4064).	0.00678294
NZ_CP042828.1|WP_147918678.1|4370267_4371182_-|ABC-transporter-permease-subunit	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	9.02159e-71
NZ_CP042828.1|WP_147918677.1|4369333_4370266_+|AEC-family-transporter	gnl|CDD|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	6.25807e-36
NZ_CP042828.1|WP_168211874.1|4360156_4361317_-|transcriptional-regulator	gnl|CDD|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	5.80155e-83
NZ_CP042828.1|WP_147919639.1|4359627_4360125_-|amino-acid-N-acetyltransferase	gnl|CDD|236132	PRK07922, PRK07922, amino-acid N-acetyltransferase.	3.88064e-93
NZ_CP042828.1|WP_147918673.1|4363034_4363961_+|NAD-binding-protein	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	9.49363e-68
NZ_CP042828.1|WP_147918667.1|4353710_4354697_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.00345791
NZ_CP042828.1|WP_147918676.1|4367431_4369321_+|substrate-binding-domain-containing-protein	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.89576e-92
NZ_CP042828.1|WP_147918672.1|4361315_4362833_+|glycerol-kinase-GlpK	gnl|CDD|198362	cd07789, FGGY_CsGK_like, Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases. This subgroup corresponds to a small group of bacterial glycerol kinases (GK) with similarity to Cellulomonas sp. glycerol kinase (CsGK). CsGK might exist as a dimer. Its monomer is composed of two large domains separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The regulation of the catalytic activity of this group has not yet been examined. Members in this subgroup belong to the FGGY family of carbohydrate kinases.	0
NZ_CP042828.1|WP_147918680.1|4373388_4374177_-|DUF624-domain-containing-protein	gnl|CDD|227865	COG5578, COG5578, Predicted integral membrane protein [Function unknown].	4.32731e-15
NZ_CP042828.1|WP_147918674.1|4364428_4365811_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	7.48761e-34

Protein sequences

>NZ_CP042828.1|WP_147918673.1|4363034_4363961_+|NAD-binding-protein
MDANSARIGVIGLGTMGAEMAQHIAAEHAGTGVLVHSRRRESAADAEAAGAHWAATPAEIGASCAVVVTVLPDLPELEQVLAGSDGLLAGLTRPTGPAGQDRRATPTVLVICSTSSPGGVRRMAADLEARTGGLLHCVDAPLSGGREGATAATLSIFAGGSAADVATATPALAPCGRVVHLGPLGAGQVAKACNQLIVAATTVALAESAVLAERSGLDLAALFDILGGGYAGSRLLEVKADKLTHRDHSPDSPARLMIKDLQFVLDEAETTGTPDEHVRLLQDLYRQVVGAGLGDLDSTVVQRYLAER
>NZ_CP042828.1|WP_147918672.1|4361315_4362833_+|glycerol-kinase-GlpK
MPDYVLAIDQGTTSSRAIIFNHSGQIVESGQIEHEQIFPKAGWVEHDPQEIWRNTREVVGLALARASLSKSDIAAVGITNQRETTVVWDKNTGEPVYNAIVWQDTRTQKIVDELGGQEGADKYKATVGLPLATYFSGPKIRWILENVEGVRAKAEAGDLLFGNTDAWILWNMTGGVNGGVHVTDVTNASRTMLMDLKTLQWDSEIAADMGIPMSMLPEIRSSSEVYGKGREGGMVPGVPIAGILGDQQAATFGQACFEVGMAKNTYGTGNFMLINTGEEAIPSENGLLTTVAYKIGDQKPIYALEGSIAVTGSLVQWLRDNLGLISEAPQVEALAKTVDDNGGAYFVPAFSGLFAPYWRSDARGALVGMTRFVNKGHIARAALEATAYQTREVVDAMNADSGVNLSELKVDGGMVANELLMQFQADILGVDVIRPEVAETTALGAAYAAGIAVGFWSGEQDVIDNWAEGKRWTPQLDADERERLHRNWKKAVTKTFDWVDEDTPA
>NZ_CP042828.1|WP_168211874.1|4360156_4361317_-|transcriptional-regulator
MSFLRCWRAPPRRNFSTLPHHALVAAPARHVGVVARCPDRHSCLERTSAQPSCTNVQAVRGKDERVREDDAYRAATMYYLQDQTMEVIAGTLGVSRSTVSRLIKAARDEGIVRISLRRPSGTGADLGHRLAATFGIVAHVVPVRERASEVQRLEQVAMVAAGLVTEWVRPDMVVGVAWGTTVTAITRHLNPSPARGSIVVQLNGAANTYAGGVTYAGDLVSTIATEFDSTPYLFPVPAFFDFAETKEAMWRERSIRRVLAVQRRVDLALFGVGALAADVPSHVYNAGYLDDTEMNELAADRVVGDVCTVFLREDGTYRDIAINARATGPTPHELRTLGRRVCVAVGAAKVPALLGALRARVATDLVTDETTARLLLERLSPESVAG
>NZ_CP042828.1|WP_147919639.1|4359627_4360125_-|amino-acid-N-acetyltransferase
MIRPALPADARAIRTIVDPYAEERILLAKDLVGYYESVPEFLVAEDPSTGDVVGCGALHVMWEDLGEVRTLAVRADRRGTGVGHELLEALLDRAREYRLTRVFCLTFEVDFFTGHGFAPIEGEVVDREVYLELLLSRDDGIAEFLDLARVKPNTLGNTRMLRQLD
>NZ_CP042828.1|WP_147918671.1|4358727_4359303_+|hypothetical-protein
MTSRGRHWEGERREREEQDTNVDEDAALEDVAIARALRAHTRTLLVMCAACAVLALVGAGALSMAGQYRSDVRVVAGLTMLGGAQLLAIAAAAIAGLGWMGIARGVGEPGSRTSQDAVRRELPQREIARTARRLAVLLRVIIALAVVGVTIWAIVDIGAVIGAAVGAVLLVQVAVVLAIVRVNVLLRPRLP
>NZ_CP042828.1|WP_147919638.1|4357136_4358618_+|DUF4038-domain-containing-protein
MLAASVAAGIGAAGAGGLPAAADPGDESTSGGQLADLPGPWENGKLMVSEDGRFLQHENGTPFFWLADTAWLLHKLSREEMGQYFDNRQEKQYNVVLLQVIPANLEFADYYGNSPFIRNNIRRPNPEYWDHITHMVEVAAQAGIYMAMNAVWRNIVKDGLMSATDAAWYGRWLARRYRDYPNIVWLIGGDAPGHEKMEVWLSLAEAIRGQDPDHLMTFHPNGRFSSSTWFHNESWLDFNMFQSGHRNYEQTYSGVSPTYNSIDVPTYWKAEDNWMYVHEDHARYPAKPTMDGEPSYEHVHQGLHDFSTPFWDDTDTRRYAYWSVFGGSCGHTYGNGGVMPMHVPSDGPVNGYDVAEYWYETMDDPGAGQLQHMKNLMLSRPYFQRIPGPTMFDGDPGFRHDRLVATYGEHYAFAYIHTGRSFSLQLGHVTGDRVVAWWYDPRTGEASRIGEYDNIGVRTFSPPGGKQVGNDWVLVLDDASQQFGKPGEPMDQS
>NZ_CP042828.1|WP_147918670.1|4355986_4356907_+|A/G-specific-adenine-glycosylase
MTAQDSPDPMALRRPILHWYRDHARDLPWRRPDTSAWGVLVSEVMLQQTPVVRVEPRWREWMTRWPTPADLAAAPTADVLRAWDRLGYPRRALRLREAARAIATEHGGIVPADEQVLRALPGIGDYTAAAVASFAYRRRAVVLDTNVRRVLARAVDGQALPPPSPRRAERERAEALLPRDGAASARWNVAVMELGALVCTARSPRCAHCPIARRCAWVAAGRPADTHADRRRSQAWHGTDRQARGRVMAALREQDQLSAAEVADLWPEPGQRDRILAALVTDGLAEAERDSDGVPLAYRLPAGGAS
>NZ_CP042828.1|WP_147918669.1|4355195_4355990_+|LysR-family-transcriptional-regulator
MPVAPFRLGYVPGVTPAKWVRTWTERHQLPLELVPLTAPTAAAALTEGTVDAALLRPPVDSETVSAIPLYTEVTVVVAAKDHALAALEAEEEATAADLAGDVLLHPLDDVYPDTSHLPATVLDHRPATTADAIELAAAGTGLLIVPMSLARLYHRRDLLYRTLAGAPGAPVLLAWLTEQTTDAVEDFIGIVRGRTVNSTRGRRLEPEADPSDQSGRDSGAPSARGGSAARARPGQGGGPAKGAYRRRPSSARGQRPGSRRRGRR
>NZ_CP042828.1|WP_147918668.1|4354766_4355162_-|hypothetical-protein
MSASADQKMKPITAAKKLGIYLPAAPEEFQSAWLTRAQLADLEKHPPEWLHTLRREGPHPRPVVAGRLGVSIAGLLRAGADEALTTAEIDALRAEPPAWLEQERQVHQEVLAEEERVRQQKAKKGPRQSRR
>NZ_CP042828.1|WP_147918667.1|4353710_4354697_-|hypothetical-protein
MSKQPRTPERRTGSSGRGQGAATGRSRSGQGATRNTRGSGTRGTADRAKRTGTRVSQGAGAGKPKGAGTGKTSGAGTGKTSGAGTPAAKPAGGKRSTTKQPSSGTATRQRPGTAAGRGSGTSSSAARRQAAQDRAATFRRRRVVVGVLALLVVAAVAFGVVRGVPVLLDRFGSDDSDATAEPTADSTGPDEEALANPVGCQPDAVSLELGLASGEVAAGSRVDVPVTITNTGQVPCLLDVGNASLELRVTSGDDTVWTTAQCPASGDERQILLAAGAVEENTITWSGRRSAADCPSDTREARAGTYRVQVNLAVDGGEVTERRALTLN
>NZ_CP042828.1|WP_147918674.1|4364428_4365811_+|Gfo/Idh/MocA-family-oxidoreductase
MSDRSARRYAVIGTGGRSRMYIDALTSSHADLGDIVAFLDPNEARMAHYDRYLAERGRSAPPHFTPESFEQMLSTARPDVLIVTSKDSTHADHIVAGLDHGLDVITEKPMTIDVPSLERIVRAAQGSTGNLTVTFNYRYSPRNSTVRRLIAEGAIGTVTSVHFEWCLDTVHGADYFRRWHRDKDSSGGLAVHKSTHHFDLVNWWLDDVPATVFALGGLRFYGAENAASRGLAPRPTLGRDLVTSGDPFALDLAADPQLKGLFLDAEHLDGYHRDQDVFGPGITIEDNLSVTVGYQGGAAMSYSLNAHSPWEGYRVAFNGTEGRLELDVVERGAVSSDRSTSGLGAGGKERPVLDPSATEAERTGQRLRPHGSRLMLQRQWSQPEEVQIPEGAGAHGGGDTMLLDDVFRGGAQDPLGRQAGYHDGVRSVIIGAAVNDSLASARAIQLADYGELLHSAVLNR
>NZ_CP042828.1|WP_147918675.1|4365866_4367432_+|family-43-glycosylhydrolase
MALPLHPDTPAHPGEYRNPVLDEDWPDPDVIRWGDGYLMVASSFNRAPGLPLLRSSDLVTWEIVGHALPGLPPAEHFALPRHGGGVWAPSIRAHRGTLYLVWPDPDHGLYVSTATDPAGPWSIPHLVLAGQGLIDPCPLWDTDGRAYLVHGWAGSRSGVKNLLTVREVSPDLRSVLAPGRTIIDGAALPGYRTLEGPKFYLRDGWYWIFAPAGGVATGWQAAFRARSVYGPYEGRTVLAQGAGPVNGPHQGAWVTDPGGADWFVHFQDRGAYGRVTHLQPMRWDSGGWPVLGNDGEPVLSHAAPVNSTRQGMRAVDGSDDFTGTLNRKWHWQANPDPAWSILSDGHLDLQPIPNDLGDLRQLPQVLSQQLPAVACTFQTSLTLSRTTEPVRTGLVLLGQEYAWIGIEVREGGAHLVCRRSGTDQSADRRRVEEPVIDQALPAAATVRLRLSSDGAGAVQLAWSTGDTDWAWVPQTFTPVEGRWIGAEVGLFATAPPGAGSPPLARYGAFQMRSTQSTPGEA
>NZ_CP042828.1|WP_147918676.1|4367431_4369321_+|substrate-binding-domain-containing-protein
MSTTGAATIAEVARTAGVSRATVSRVMNGRATVDPAMAARVRKAARELNYSPSTVARSLSLGRTQTVALLVPDLGNPMFQQVLRGANQAATKAGYRILVADSIEEPEREAELAIEARRRCDALILCSPRMPEDQLNEVLTATAPVVLVNREPHGSDVPALAVDYATGIRTLAEHLIGLGHRRFIYLAGPVTSASNTARLEGLALLQAAHPEISIQHSPCGSMIEDGYAALEAVLNSQATAVLAFNDLVAFGLLGKLNETGVGVPRGISVAGFDDIAFAKYATPALTTMSVPQMDLGRHAWDQLHQLLVGEAESTSLFFRPRLIERVSTGPAPVQPTTAPAAPEAGSLPLWSRDDDAGVLRAAGSSLARYERHPAMPDVHAPRPYLHPVHTWNGTPLTEISPLDHRHQYGVSLAVAQVNGSSFWGGRTYVRDAGPTLLQIHGTQVSHDMTLVGPALTEQLTWFGHDGAELLTERRRLTARTLPAQHGWELTWQSLLHASAGPVTIDSPATQGRTGAGYGGIFWRFPDDGEASITCADGTGEEVAHGSTSPWLLLSRAGDRPWTALLLQQGEVRPWFVRSTDFLGAGPALAWSESLHIPAGDNLEVGLRAVLFDGVVGADEVTELIESVTE
>NZ_CP042828.1|WP_147918677.1|4369333_4370266_+|AEC-family-transporter
MTAVLTALGTMTLIALAGWLLATTRVLGPEAPKVLARVVFTLSTPSLLITTIGSANLELLLTPAALSTWVSTLIVAAIAVVIFAFLLRTDRSVTTIGALSASYLNAGNLGIPVAVYVLGDALAVVPTMLLQLLVLAPVAFAVGDARPGRRRRDAVLRALRSPLTVAALLGLALALVPWQLPTVLWEPLHALAATAAPLALLTLGMSMVRSAPPPGAPKPALDRRHWAGVLVATAMRTLVHPALTYLVADLVGVPPEARFAVVLMAALPTAQNVLVYAMQFDAGQRLARDAQVITTFASLPLMVAVVALLH
>NZ_CP042828.1|WP_147918678.1|4370267_4371182_-|ABC-transporter-permease-subunit
MAARSETTITYRPDRLRKPTSGRRVFSVVNSAVLIAFALVCLLPFLHVIGSSLANPGELATRAFVIIPREFTLDAYRYVLSTPTIFRAMGVSMFVTVVGTFLSLLVTSLMAYALGKRYLRGRRVINFLVVFTMLFSGGMIPLFIVVNGLGLLDSVWSLILPFTVNAFNFVIMRSFFQSIPDSLEEAARIDGCSEFGVFVRIVLPLSVASIATIGLFYAVAYWNTYMWAILFINDSTLWPIQVLLRQIVIVASGLNADASVVDVVPPAQSVKMAVIAVATLPMLIVYPFIQRYFVKGALIGSVKG
>NZ_CP042828.1|WP_147918679.1|4371181_4371661_-|DUF4064-domain-containing-protein
MSARAEQRRRPQDEAVPPPAPSIRRTAELWLTGIGAVLATLFLGGFALVVNRLDEAAFADVVRPVLLGGAEDLSSAEAFEAGRTLGAWFGFTLLLVLALAAVAVLLTRSRPWRRAPGWWLLAAGAVCLLGSQLIAYPIAFFFFLGAGLFAARPVRDGSS
>NZ_CP042828.1|WP_168211875.1|4371644_4371809_-|hypothetical-protein
MPTLENVSSLAPATAGLQQAIDEAAAAGGGPRNVVISTCDRIRLDVQGDDERQG
>NZ_CP042828.1|WP_168211876.1|4371874_4373068_-|extracellular-solute-binding-protein
MRNALTSGMFWDVEPYLSEFDNLSQIPQATIDVARLDGHLYGIPFQKPIARYGVLVRQDWLDNLGLETPHTLAELAEVAQAFAEDDPDGNGEDDTTGFIERSESFSLSFRIIAGYFGAGDRFELDDAGNVVPAYTTDAWKEAMAWYRSVYESGGMNQEFVTMQKDNQRDAIARGEGGIVITGLFEARGYLELAESIDPETPMDWAQINDMTAGDVERRIVSDTNGGMGGWLAINTQTVETEEELREVLGFIDSLLDEEPFTLMTQGIEGEHYEVDGEGVYSRINQTEWEQEVQPYASSRPADNVIIFTSDNEYVNRADELMAESAEYAVTNPAQSLSSETYDRQWSTIDQTVMDAFNRYMVGELDMAGYEEAIESVRSQGLDDIITEFTESYNSVNG
>NZ_CP042828.1|WP_168211877.1|4373088_4373283_-|hypothetical-protein
MTAQLPGMSMLHTPTTPDPNGPIHEALVDYTGTDFEMQWVPDASKEEKINAALASGTLADTSPP
>NZ_CP042828.1|WP_147918680.1|4373388_4374177_-|DUF624-domain-containing-protein
MLSYEGLVRLNHLLSGFYRLLWLNLLWVATTVVGLGIFGVGPATYAFAKYVDRWFRLGELPPAAATFRRYATELRWRPVLVSWVLLAVAVVIGVNLLSAANWYLRVANLLALVVLAVIAAYVYFVLAALDVTTIRSTLSAALLLGVGSLHWTIIGTTAVAALYWVMYRFALPLLPVVGIALPMTVVGLIVRGVFRQLAEVDAEEASAANGSTGGGTAGPVGTANPARTEISARAERNDAHADLAHPDRPGIAERHLQKGSAV

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP042828_12	12.1|3328180|19|NZ_CP042828|CRISPRCasFinder	3328180-3328198	19	NZ_CP042828.1	3328210-3328228	1	0.947
NZ_CP042828_12	12.1|3328180|19|NZ_CP042828|CRISPRCasFinder	3328180-3328198	19	NZ_CP042828.1	3328228-3328246	1	0.947

1. spacer 12.1|3328180|19|NZ_CP042828|CRISPRCasFinder matches to position: 3328210-3328228, mismatch: 1, identity: 0.947

ttcactggcgctcgggtct	CRISPR spacer
ttcgctggcgctcgggtct	Protospacer
***.***************

2. spacer 12.1|3328180|19|NZ_CP042828|CRISPRCasFinder matches to position: 3328228-3328246, mismatch: 1, identity: 0.947

ttcactggcgctcgggtct	CRISPR spacer
ttcactcgcgctcgggtct	Protospacer
****** ************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042828_3	3.2|1631971|21|NZ_CP042828|CRT	1631971-1631991	21	NZ_CP010801	Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence	180895-180915	1	0.952
NZ_CP042828_3	3.1|1631932|21|NZ_CP042828|CRT	1631932-1631952	21	NZ_CP035509	Haematobacter massiliensis strain OT1 plasmid pOT1-9, complete sequence	49205-49225	2	0.905
NZ_CP042828_1	1.2|268920|25|NZ_CP042828|CRISPRCasFinder	268920-268944	25	NC_006824	Aromatoleum aromaticum EbN1 plasmid 2, complete sequence	13730-13754	3	0.88
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	537920-537947	3	0.893
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	703459-703484	3	0.885
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	1077992-1078017	3	0.885
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	1078991-1079016	3	0.885
NZ_CP042828_1	1.2|268920|25|NZ_CP042828|CRISPRCasFinder	268920-268944	25	NC_022043	Paracoccus aminophilus JCM 7686 plasmid pAMI5, complete sequence	98535-98559	4	0.84
NZ_CP042828_1	1.2|268920|25|NZ_CP042828|CRISPRCasFinder	268920-268944	25	NC_048029	Sphingomonas phage Scott isolate SPS, complete genome	1635-1659	4	0.84
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP050092	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence	267067-267094	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	408249-408276	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	140429-140456	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	108909-108936	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	94142-94169	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	408249-408276	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	167140-167167	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NC_012848	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence	764569-764596	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	835976-836003	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	433106-433133	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	809330-809357	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	164364-164391	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	235886-235913	4	0.857
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	1186867-1186894	4	0.857
NZ_CP042828_1	1.4|269019|25|NZ_CP042828|CRISPRCasFinder	269019-269043	25	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	200428-200452	4	0.84
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	1176284-1176309	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	1177283-1177308	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NC_030931	Pseudomonas phage phi2, complete genome	8661-8686	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	MN908685	Microbacterium phage PauloDiaboli, complete genome	110733-110758	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	MN585990	Microbacterium phage Azizam, complete genome	13459-13484	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1694261-1694286	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	MT310863	Streptomyces phage Issmi, complete genome	14738-14763	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	KR053195	Gordonia phage GMA1, complete genome	6133-6158	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	405795-405820	4	0.846
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP010864	Marinovum algicola DG 898 plasmid pMaD9, complete sequence	50800-50825	4	0.846
NZ_CP042828_6	6.1|1953196|27|NZ_CP042828|CRISPRCasFinder	1953196-1953222	27	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1394878-1394904	4	0.852
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	105741-105766	4	0.846
NZ_CP042828_1	1.2|268920|25|NZ_CP042828|CRISPRCasFinder	268920-268944	25	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1890212-1890236	5	0.8
NZ_CP042828_1	1.2|268920|25|NZ_CP042828|CRISPRCasFinder	268920-268944	25	NZ_LR594664	Variovorax sp. RA8 plasmid 3	389972-389996	5	0.8
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP050098	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence	142167-142194	5	0.821
NZ_CP042828_1	1.3|268968|28|NZ_CP042828|CRISPRCasFinder	268968-268995	28	NZ_CP053440	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eF, complete sequence	142806-142833	5	0.821
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1537587-1537612	5	0.808
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	MF766045	Streptomyces phage Daudau, complete genome	14433-14458	5	0.808
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	MT701597	Streptomyces phage Sentinel, complete genome	12225-12250	5	0.808
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1415033-1415058	5	0.808
NZ_CP042828_6	6.1|1953196|27|NZ_CP042828|CRISPRCasFinder	1953196-1953222	27	NZ_CP020333	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM170, complete sequence	27379-27405	5	0.815
NZ_CP042828_6	6.1|1953196|27|NZ_CP042828|CRISPRCasFinder	1953196-1953222	27	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	45962-45988	5	0.815
NZ_CP042828_6	6.1|1953196|27|NZ_CP042828|CRISPRCasFinder	1953196-1953222	27	MN234196	Gordonia phage CloverMinnie, complete genome	44608-44634	5	0.815
NZ_CP042828_8	8.1|2109665|27|NZ_CP042828|CRISPRCasFinder	2109665-2109691	27	NZ_CP019938	Ketogulonicigenium robustum strain SPU_B003 plasmid unnamed1, complete sequence	60205-60231	5	0.815
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	162459-162484	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	182921-182946	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3766848-3766873	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	163526-163551	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	465789-465814	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	422020-422045	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	182921-182946	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	182930-182955	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	182948-182973	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	182920-182945	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	162474-162499	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	162472-162497	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	162470-162495	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	8150-8175	5	0.808
NZ_CP042828_13	13.1|3435418|26|NZ_CP042828|CRISPRCasFinder	3435418-3435443	26	MH727561	Mycobacterium phage Serendipitous, complete genome	20679-20704	5	0.808
NZ_CP042828_2	2.1|934708|31|NZ_CP042828|CRISPRCasFinder	934708-934738	31	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	284218-284248	6	0.806
NZ_CP042828_3	3.5|1632082|30|NZ_CP042828|CRT	1632082-1632111	30	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	869505-869534	6	0.8
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_LR134450	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence	43461-43486	6	0.769
NZ_CP042828_5	5.1|1858179|26|NZ_CP042828|CRISPRCasFinder	1858179-1858204	26	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	29127-29152	6	0.769
NZ_CP042828_8	8.1|2109665|27|NZ_CP042828|CRISPRCasFinder	2109665-2109691	27	MT711975	Streptomyces phage Alderaan, complete genome	26375-26401	7	0.741
NZ_CP042828_8	8.1|2109665|27|NZ_CP042828|CRISPRCasFinder	2109665-2109691	27	MK305888	Streptomyces phage Austintatious, complete genome	19952-19978	7	0.741
NZ_CP042828_2	2.1|934708|31|NZ_CP042828|CRISPRCasFinder	934708-934738	31	NC_008010	Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence	488294-488324	8	0.742
NZ_CP042828_3	3.5|1632082|30|NZ_CP042828|CRT	1632082-1632111	30	NZ_CP050101	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b6, complete sequence	116500-116529	8	0.733
NZ_CP042828_3	3.5|1632082|30|NZ_CP042828|CRT	1632082-1632111	30	NZ_CP053442	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eD, complete sequence	116373-116402	8	0.733
NZ_CP042828_8	8.1|2109665|27|NZ_CP042828|CRISPRCasFinder	2109665-2109691	27	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	322031-322057	8	0.704
NZ_CP042828_8	8.1|2109665|27|NZ_CP042828|CRISPRCasFinder	2109665-2109691	27	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	576876-576902	8	0.704

1. spacer 3.2|1631971|21|NZ_CP042828|CRT matches to NZ_CP010801 (Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence) position: , mismatch: 1, identity: 0.952

cggccgccgaagcagctgctg	CRISPR spacer
cggccgccgaagcagctgccg	Protospacer
*******************.*

2. spacer 3.1|1631932|21|NZ_CP042828|CRT matches to NZ_CP035509 (Haematobacter massiliensis strain OT1 plasmid pOT1-9, complete sequence) position: , mismatch: 2, identity: 0.905

cagccgacgctccggctgctg	CRISPR spacer
tcgccgacgctccggctgctg	Protospacer
. *******************

3. spacer 1.2|268920|25|NZ_CP042828|CRISPRCasFinder matches to NC_006824 (Aromatoleum aromaticum EbN1 plasmid 2, complete sequence) position: , mismatch: 3, identity: 0.88

gaccagaagaacgagcaggccgata	CRISPR spacer
ggccagaagagcgagcaggccgaga	Protospacer
*.********.************ *

4. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 3, identity: 0.893

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatgttggtgaccgagggctcgagca	Protospacer
  ***** .********************

5. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.885

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgagcgcgccgagcgccacg	Protospacer
********* ** ************ 

6. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 3, identity: 0.885

acggacctccgccgtcgcccggctca	CRISPR spacer
acggacctgcgccgtcgcgcggctta	Protospacer
******** ********* *****.*

7. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 3, identity: 0.885

acggacctccgccgtcgcccggctca	CRISPR spacer
acggacctgcgccgtcgcgcggctta	Protospacer
******** ********* *****.*

8. spacer 1.2|268920|25|NZ_CP042828|CRISPRCasFinder matches to NC_022043 (Paracoccus aminophilus JCM 7686 plasmid pAMI5, complete sequence) position: , mismatch: 4, identity: 0.84

gaccagaagaacgagcaggccgata	CRISPR spacer
acccagaagggcgagcaggccgata	Protospacer
. *******..**************

9. spacer 1.2|268920|25|NZ_CP042828|CRISPRCasFinder matches to NC_048029 (Sphingomonas phage Scott isolate SPS, complete genome) position: , mismatch: 4, identity: 0.84

gaccagaagaacgagcaggccgata	CRISPR spacer
gaccagaaaatcgagcaggccgagg	Protospacer
********.* ************ .

10. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP050092 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

11. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

12. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

13. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

14. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

15. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

16. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

17. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NC_012848 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

18. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

19. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

20. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

21. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

22. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

23. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 4, identity: 0.857

gccgatg-cggtgaccgagggctcgagca	CRISPR spacer
-acgatattggtgaccgagggctcgagca	Protospacer
  ****. .********************

24. spacer 1.4|269019|25|NZ_CP042828|CRISPRCasFinder matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

ggttccgctaccagcgccaccgatg	CRISPR spacer
tgttccgcaaccagcgccacccatc	Protospacer
 ******* ************ ** 

25. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgagacgagcgcaccg	Protospacer
************** *******  * 

26. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgagacgagcgcaccg	Protospacer
************** *******  * 

27. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NC_030931 (Pseudomonas phage phi2, complete genome) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgtgccgcgcgccatt	Protospacer
************ **** ******..

28. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to MN908685 (Microbacterium phage PauloDiaboli, complete genome) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgagccgaacgcggct	Protospacer
******************.*** .*.

29. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to MN585990 (Microbacterium phage Azizam, complete genome) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgagccgaccgcgccg	Protospacer
****************** ***  * 

30. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
accagccgaccgagcccagcgtcacc	Protospacer
 * ************* ****.****

31. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to MT310863 (Streptomyces phage Issmi, complete genome) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
tcgagccgagcgagccgagcgcggcc	Protospacer
.******** ************ .**

32. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to KR053195 (Gordonia phage GMA1, complete genome) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
cgcagccgaccgggccgagctccacc	Protospacer
*  *********.******* *****

33. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgcggcgagcgccgcg	Protospacer
************ * ********.* 

34. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP010864 (Marinovum algicola DG 898 plasmid pMaD9, complete sequence) position: , mismatch: 4, identity: 0.846

ccgagccgaccgagccgagcgccacc	CRISPR spacer
caaagctgaccgtgccgagcgccacc	Protospacer
* .***.***** *************

35. spacer 6.1|1953196|27|NZ_CP042828|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 4, identity: 0.852

gcgtcgagcggggccagtcgcgcggag	CRISPR spacer
ccatcgagcgcggccagtcgcgtggag	Protospacer
 *.******* ***********.****

36. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 4, identity: 0.846

--acggacctccgccgtcgcccggctca	CRISPR spacer
cgacga--ctccgccgtcgcccggctcc	Protospacer
  ***.  ******************* 

37. spacer 1.2|268920|25|NZ_CP042828|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 5, identity: 0.8

gaccagaagaacgagcaggccgata	CRISPR spacer
tgccagaagaacgatcaggccgacg	Protospacer
 .************ ********..

38. spacer 1.2|268920|25|NZ_CP042828|CRISPRCasFinder matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 5, identity: 0.8

gaccagaagaacgagcaggccgata	CRISPR spacer
gacaagaagaacgagcaggccatcc	Protospacer
*** *****************. . 

39. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP050098 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b4, complete sequence) position: , mismatch: 5, identity: 0.821

gccgatg----cggtgaccgagggctcgagca	CRISPR spacer
----atgatattggtgaccgagggctcgagca	Protospacer
    ***    .********************

40. spacer 1.3|268968|28|NZ_CP042828|CRISPRCasFinder matches to NZ_CP053440 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eF, complete sequence) position: , mismatch: 5, identity: 0.821

gccgatg----cggtgaccgagggctcgagca	CRISPR spacer
----atgatattggtgaccgagggctcgagca	Protospacer
    ***    .********************

41. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 5, identity: 0.808

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgaccgagccgagcacgttg	Protospacer
********************.*  . 

42. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to MF766045 (Streptomyces phage Daudau, complete genome) position: , mismatch: 5, identity: 0.808

ccgagccgaccgagccgagcgccacc	CRISPR spacer
tcgagccgagcgagccgagcgcggac	Protospacer
.******** ************ . *

43. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to MT701597 (Streptomyces phage Sentinel, complete genome) position: , mismatch: 5, identity: 0.808

ccgagccgaccgagccgagcgccacc	CRISPR spacer
tcgagccgagcgagccgagcgcggac	Protospacer
.******** ************ . *

44. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgagccgaccgagccgagcgccacc	CRISPR spacer
ccgagccgatcgagccgcgcgccctt	Protospacer
*********.******* ***** ..

45. spacer 6.1|1953196|27|NZ_CP042828|CRISPRCasFinder matches to NZ_CP020333 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM170, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgagcggggccagtcgcgcggag	CRISPR spacer
ctgtcgatcgaggccagtcgcgcggac	Protospacer
 .***** **.*************** 

46. spacer 6.1|1953196|27|NZ_CP042828|CRISPRCasFinder matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 5, identity: 0.815

gcgtcgagcggggccagtcgcgcggag	CRISPR spacer
tcgtcgagcagggccaggcgcgcgccg	Protospacer
 ********.******* ******  *

47. spacer 6.1|1953196|27|NZ_CP042828|CRISPRCasFinder matches to MN234196 (Gordonia phage CloverMinnie, complete genome) position: , mismatch: 5, identity: 0.815

gcgtcgagcggggccagtcgcgcggag	CRISPR spacer
tcatcgagcggggcgagtcgcgcgccg	Protospacer
 *.*********** *********  *

48. spacer 8.1|2109665|27|NZ_CP042828|CRISPRCasFinder matches to NZ_CP019938 (Ketogulonicigenium robustum strain SPU_B003 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggggcggtgcgcacggggcgaagggcg	CRISPR spacer
tgcgcggcgcgcacggggccaagggca	Protospacer
 * ****.*********** ******.

49. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

50. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

51. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
ggcgacctcggccgtcgcccgggtca	Protospacer
.  ****** ************ ***

52. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

53. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
gtcgacctccggcgtggcccggctca	Protospacer
.. ******** *** **********

54. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
gcggacctccggcgtcgccctgctgt	Protospacer
.********** ******** ***  

55. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

56. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

57. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

58. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

59. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

60. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

61. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
acagccctccgccgtcgcccggccgg	Protospacer
**.* ******************. .

62. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
tatgacctacgccgtcgccgggctca	Protospacer
   ***** ********** ******

63. spacer 13.1|3435418|26|NZ_CP042828|CRISPRCasFinder matches to MH727561 (Mycobacterium phage Serendipitous, complete genome) position: , mismatch: 5, identity: 0.808

acggacctccgccgtcgcccggctca	CRISPR spacer
gtggacctccgcgctcgcccggctct	Protospacer
..**********  *********** 

64. spacer 2.1|934708|31|NZ_CP042828|CRISPRCasFinder matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 6, identity: 0.806

accgaccgcgccgacggctccagtggggtgg	CRISPR spacer
gccgtccgcgccgacggctccagcggtgcag	Protospacer
.*** ******************.** *..*

65. spacer 3.5|1632082|30|NZ_CP042828|CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 6, identity: 0.8

cggctgaggctgccacggaagctccggttg	CRISPR spacer
cggctgaggctgctgcggaagctgctgcgg	Protospacer
*************..******** * *. *

66. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_LR134450 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 8, complete sequence) position: , mismatch: 6, identity: 0.769

ccgagccgaccgagccgagcgccacc	CRISPR spacer
agaagccgaccgagccgagcgcgatg	Protospacer
  .******************* *. 

67. spacer 5.1|1858179|26|NZ_CP042828|CRISPRCasFinder matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 6, identity: 0.769

ccgagccgaccgagccgagcgccacc	CRISPR spacer
tctcgccgaccgagccgagcgccttg	Protospacer
.*  ******************* . 

68. spacer 8.1|2109665|27|NZ_CP042828|CRISPRCasFinder matches to MT711975 (Streptomyces phage Alderaan, complete genome) position: , mismatch: 7, identity: 0.741

ggggcggtgcgcacggggcgaagggcg	CRISPR spacer
tcggcggtgctcacggggcgaagctgc	Protospacer
  ******** ************    

69. spacer 8.1|2109665|27|NZ_CP042828|CRISPRCasFinder matches to MK305888 (Streptomyces phage Austintatious, complete genome) position: , mismatch: 7, identity: 0.741

ggggcggtgcgcacggggcgaagggcg	CRISPR spacer
tcggcggtgctcacggggcgaagctgc	Protospacer
  ******** ************    

70. spacer 2.1|934708|31|NZ_CP042828|CRISPRCasFinder matches to NC_008010 (Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence) position: , mismatch: 8, identity: 0.742

accgaccgcgccgacggctccagtggggtgg	CRISPR spacer
cgttcacgcgccgacggcggcagtggggtgg	Protospacer
  .   ************  ***********

71. spacer 3.5|1632082|30|NZ_CP042828|CRT matches to NZ_CP050101 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b6, complete sequence) position: , mismatch: 8, identity: 0.733

cggctgaggctgccacggaagctccggttg	CRISPR spacer
aggctgaggctgccatggaagccaagcggg	Protospacer
 **************.******.  *   *

72. spacer 3.5|1632082|30|NZ_CP042828|CRT matches to NZ_CP053442 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eD, complete sequence) position: , mismatch: 8, identity: 0.733

cggctgaggctgccacggaagctccggttg	CRISPR spacer
aggctgaggctgccatggaagccaagcggg	Protospacer
 **************.******.  *   *

73. spacer 8.1|2109665|27|NZ_CP042828|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.704

ggggcggtgcgcacggggcgaagggcg	CRISPR spacer
tcggcggtgcgcacggggcgacctcgt	Protospacer
  *******************      

74. spacer 8.1|2109665|27|NZ_CP042828|CRISPRCasFinder matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.704

ggggcggtgcgcacggggcgaagggcg	CRISPR spacer
tcggcggtgcgcacggggcgacctcgt	Protospacer
  *******************      

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	349907 : 383260	32	Enterobacteria_phage(33.33%)	protease,plate,tail	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP042828|349907:383260|DBSCAN-SWA
GATGCTGCCCGGCTGGGGGCACGGCCTTCTGGTGGTGAGCCTCGCCGCGGCCTGGTGGCGAGACCGCGAGCTCGGTAAGGACCTGACCCTGATCGGGCTCGGGGTGGCGATCGTGTCCACCACGTCGGTGGAGGCGGACGTGCACTGGGACCGGTTCTTCACCATCGGGATCGTGCTCGCGCTGGCCGTGGCCACGCCACTGCTGGTGGACCGGTTCGTCTACCGCCGGCGGGCGATCCGGTTCCCGTGGCGGACCGGGAAGAAGTGGTCCCCGATCGAGCGCAGCTACCTGGTGCTGGTGCCACTGCTGGGCTGGCTGATCCTGCCGTTCTACTTCATCACCTCCGGTGCTTACCTGAACTGGCCGTACATCACCGACGGCAGCATGCTCGCCCGGTTCTTCGTCGGGGTGAACTTCGTGGGCACCTGGGACGAACTGTTCTTCATCTGCACCTGCTTCGCGCTGCTGCGCCGGCACTTCCCGGTGTGGGCCGCGAACCTGCTGCAGGCCACGATCTTCGTCTCGTTCCTGTGGGAGCTCGGCTACCGGGAGTGGGGGCCGTTCCTCACCGCACCGTTCGCGCTGCTGCAGGGCTGGATCTTCACCAAGACCGGGTCGCTGACCTACGTGCTGATCGTGCACCTGCTCTTCGACGTGATGGTGTTCCTGGCGATCGTGCACGCCCACAATCCCGGCTGGATCCCGATCTTCCTGGTGTGACTCCCGGTTTCGGGCTCGCGAGTGGGTTAACTGGGGCCATAACCCCAGTGAACGCACACACGAGCGCAGGGACCGGGTGTGGGCACCCACTTCTCAGGCCGATCGGCGCAGAGATCTTGCCGCCTCGCAGCCGGGACCACAGGGCCAGAGCTCGCCGCGATAACCACGGCCACGAGCGGTCGCGAAGATCTCCGCCGCGAGCTGGCAGGCCGCGTAGTAGACGTCCACCCACTCCGCGCGGAGGGTGACGACGTCCCGCGCTGCGGTCGCCCGGTCACGGCGGATGTCTGCACCCCGGCTACCTTCGTGCGCCGCGCGACCATCGACCTCGACGACGAGCCGGTGGGCCGCATCGACGAAGTCGCGGCGGATGGTCCGCCCTGCGGCCCGATCGGCGACCGCCATCCGCATCTCGGGAAGCCCATGGGCTTGCACCACGCGGATGACGAAGTCGACCTCGAGCACGCTCTCGGCGCCTTCGGCCACGATGCCGAGGGAGAGTTCGAGCGCGCGCCGATGACGATGGCTGCGCCGCTGCTCGAGCTCGGCCATGAGCTCCTCGGCGGTGGTCCTGTGCCGCTGCACGGCCCGTGCTGCTGTGGCGATCGCGTCTTCCCGGGAAGCCGTGGGGGTATCGCCAAGGTCGATCACGGTGAAGGCCGGCGCGGTGACCAGGAGGCCCCTGCGGCTGACGGTCAACAGCCGATGCCGGCGCCGCACCCGCGTGGCCGGTCGCCGCTGCCGCCCCGCGTTGGCCGGGACGTCCACGTGCACGAGCTGGGGCTGCCGGGACGCCAGCCCGAGTATGAAGGCTGCGGACTCCAGCGACAGGGCGGCATCGTCGCCGTAGTAGAGCAGCGCGGCGCTGGCCCGGGCGAACCAGCCGAGAGGCTGATCGTGCACCGCGTAGACACCGGGATGCACGCGCTGCCACGACCCACGAGCCAGCTTCCACCGGACCGCCTCTGCGCTTCGTTCCGCCAGGGCCTGTGCGCGGGAGACGATCCCGAACTGCGCTGCCGCCAGTCGGGAGAGGTCCATGTATCCACCCTGCCGTGCCGGCGGCGCTGCGGTGCCGGCTATCCACAGGCTCGGTGCGACCCAGCGAGTTGGCGGGTGGGATTGCTGGGGTCATTGCCCCAGCAATCCCACACACGAGGCAGAGCGCCGTGATCACCCCTTCAGCCCGGTGCTCGCCAACCCCTGGATGAACTGCCGCTGGGCGGCGATGAACACGATCAGCACCGGGATCACGGTGAGTGTGGTGGCGGCGAGCTGCACGTTCCAGATCGGCCCGCCGTAGGCGTCCACGTACTGGGTGAGTGCCTGCGGCAGATCAGTCCCGGTCGGCAACCGTCGCCAGCACCACCGGGTCAGCGCACCCCGCCGCGAACCCGTCGATCCGCCGCTGGATCTCCCGGCCGAGTACCCAGGTGCCGATCTTCTCGGCGAGCGGGGCCAGCCAGTTGGGCCGGCAGGAGAAGTTGTACTTCCACACTGCCCGCGCCTGCCCTGGGCCGGCTTCCTCGAAGCGCCAGCCTCCGGCCATCTTCGCGAAGAACCACGGCCCGGTGACCATTCGCATCCCGACGTTGCGGGGCGGCGCGTAGGACACGTACTCGCTGACCATGCGCGCTCCCCACCGGTGCACGGTCAAGGTGCGCACGCCCTTGCCCGGGTGTGTGGCGCCGTCGAGGAAATGCTGACGGCGGACGAACCGGTCCCAGCGCAGCCGCACCTCGCCGGTGGTCTGGGAGAGGGCGAACGCGGTCTGCGCATCCACGGGAACTGTCACCTCTGCACTCACCACCGGCATGGGGAAGATGGTGCCACGCGCGCCCCCGCGGTCACCAGCCGCACCGTGCCACCCTCGGCTCCGCGGTCACCACCCGCTCCCGCGCCGAGCAGCCGGTCCCACCCGCCGAATGAGGACTACCCTCGTTCCGGCGTGTGCGCGCGAGCCGATCGCGGCCGGCGCCCAGGTGGCCGAGCCGGCCGCGGTGCTGTTCGTGGTGCTGCCTACGCTCCGCGCTGTCCACGGCCCGCCCGCACCTGACGACGCCGTACCCGGAGACTGAGGAGAGGAACGATGGGAGAACTGCTGGGGGTCACCCCGCTCGAGGCCCTGGCCGTGGTGCTCGGTACCGCCGGGATGTACGTGACCATGGTGATCATCATCAAGCTGGTCGGGCAGCGGATGCTGTCCAGCATGTCCAGCTTCGACGTGGCGGCGGTGATCGCGTTCGGCTCGATCCTCGGCCGCGCAGCGCTCGGTGAAGCACCGCGACTGGCCGCAGGCATCCTCTCCCTGGCCACCCTGGTGGCGATGCAAGCGGTCGCCGGACTGGTCCGGAGCGTGCGCCGCGGCGGTCGGCTGATCGTGTCCGAGCCCGTGCTGCTGATGGCTGGATCCGCGGTGGTCGAGGAGAACATGCGGCATTGCCACGTGGTGCTCGCCGAATTGCAGTCCCGGCTCCGGCAGGCGGGTATCCGGCACCGCGGCGAGGTGGCCGCCGTCGTGTTCGAGCCCTCCGGCGCGATCAGTGTGCTGCGCCGCGGCGACGGGATCGAGGAGAACCTGCTCGACGGCGTCCGCGGCGGCGAGCTGGTGCCCCGCGAACTGCTGCGCTGAGCGTCGGACCGCCCCGACCCCGGTGCGCGAGACTGCCCTGCCACCGGCGCTCTCACGCACCAGGGCGGCCCCGATAGTGTGTGCTGTATGGGTCGAAAGCTGGGACAGCTGAGGGCGCGGGCGCGCATCGTCGGCGCCGGCGTGGCGGCCGCGCTGGTGGCCACCACCCTCGCGGGCTGCTCGCTGTTCGGCCTGGATGAGGAGCCGGCGCTGGAGTGCCCGGGTGAGTCTGCGCCCACATCCGCCCCGGGCGAGGCGCGGGTGATGCTCACGATCGCAGAGGGAGCCAGCGCCTGGGATCTGACCTGGGTGGTCTACGACGACGGCTCAGTGGCGCTGCTGGACGGGCAGCAGCAGGCGGAGACCGGCACGAACGCACTGGCTGCGGCTGGACCACTGCCCCAGTACGCGGGCGGTCCCTACACTGAACAGCCCGGCTCCTGGAGTAGCGGGTACCTGCTGCCGTGTGCGCTGGCCGAGCTGCGCCAGCGCGCCGACGACGCCCTGTTCGGGTCACCGGAGTACGGCAGAGTGTCGATCACCGATAACCCCTGGACCTACGTCAGCTACGACAACGGTGCCTCCCGCGCTTCCGTGGAGGTCTACGCCTTCGACACCGGCTACACCGAGGGCCTGGAGTGGTCCGAACGGCGCGCGCGGGAGCGGCTGGCCGCGGTGACCCACTTCCTCGAAGCCAACCTGGTCCGCACCGGTGAGACGATCCCGGTCTCCCGCGTGCAGGTGGACGGCGCCGGCGAGGTCGGTGAGGGCTTCGAATGGCCTGGGCCGGCTCCCGCCGAGCTACTCGGCGAGCAGGGCTGCGGTGTGCTTACCGAGGATCCGGCGACGGCGGTGTACGAGTTCGCGCAGGAGCCCGGGTTGGGCGAGGCGAGCTCAGAGCTGACAGTTCGCGCGTTGCCACCCGGGGTGTCCGGCTGTCGGTAGGTGAGGCTCGCCAGGGAGCCGGCTGCCCTGGGCAGGCAGGCCTCGGCGAGATCAGACGACCGCGGTGATGATGCTCGGCGCGATCAGGGCCATCAGCACGCTGAGGACTGCGGTCACGCCTAGAGCGAGGCCGGCGCCGGCGGCCGCCTTGGGCTTGCCGGTGCCACTGAGCCCGATGCCACCGGCGATCAGGGCCACCAGAGCGAAGACGGTGGTGACGATTCCACCGATCAGGTTGAACCGGAGCGAGACCGCGCTGGCGCTCAGGTCGTACCTGTGCATCAGATAGGGCAGCAGCAGGGCGAGCACCTGCTGGACCAGTCCGATCAGCACCACGAGGATCCCGGCCACCAGCGCCAGCCGACCGGCGGGATTCCTGCCCCTCCCGGCGCCGGGCTGGTACGCCGTCGCTGCATAGCCGGTGTGGTGTGGATCGGGTCCGAAGCCTGTGCTCATAGCCGCTCATCGTGCCAGCACCGGGCACCGAGCGTCATCACTGGTAGATCAAGGGCATGGTCACATTCAGAAGCAGGAACAGCAGGGTGGAGGTTCCGAGTGCCAGACCGGCTGCCGCAGCCCCGCGCGGTCGCGGCCGGCCAGCGAGGCCCACGGCGCCGGTGATCACCGCCAGCACAGCCAGCACGGCCTCGCCGACGGTGAAACCGAGGTCCACGGCCCGCCACAGTCCGTCGGACCCACCGCCCACATCCATCGGCATCGACCAGATGACTAGGATCCGCGCCAGCTGGAGCAGCGTCAGCGCCACACCGACGATCAGTGCGATCCGCCCGGGCACGTTGGTGCTTCGGTTCCCGCCTCCGGGCGGCGGAGCGACGAAGGCATTCGGGTTGTAGGACGGCGGGTCGTAGGAAGACATGGGCAGTCACCCTGCCAGGGCGGACACTGGTCCGGGCGGGCATTGACGGGGAGAACTCCCCACCGCGTGGGCCGGAATCGGACAGAACTGCCCACCGTCGCCGATGCTCCGCGGCGATCAGCACCCTTACGCTGACCGGACCATGACGAAGGGAGTGGCCGTGCGCCGTCGATCGACACTGCAGGGGGACCGTTCGAGGAGGAGACACGGGAGGTCGAGACTGGGCCGCGCGGTCGCGCTCGGGGCGGCAGCAGTGACGGTGCTCGCCGGGATGACCGCGTGCAGTCCGTCCCCGATCGACCCGACCGAGGACTGTACCGATGCGGGCAGCCAGCCGGCCGGTGAACCCGGCTCGGCGGAGGTGCTGCTGACCTCCAGCGGGTACGTCCTCTACGCCGACGGCTGGATGGTCATCACCGCCGAGGACGAGGCGAGCGCGGCGAACGCGATGCGGGTGCCGTTGATGGCACCGGCCCCGCCAGCCGGCGATCGCTGGCAGCCCGCCTACCTGGGCAGCTGCCAGCTGGAGGCGGTGGACGCGCTGGCCGCAGAGGAGCTCGTCGAGGGAGACCTGGGGGACCCGATCGTCACCGATGCCAGCACGACCACGATCACCTACTACGGCGGTGAGGAGCCGGTGAGTAGCAGCGCCTACGCGCTCGGGAGCGAAAGTTCCGATCTGAGCCGGGCGGACCAGCAGGGCCGCGAGGTGCTCAAGGCCTTGATCGCCGCCCTGGACGAGGCGACGGTCACCGGCGACGTCCTGCCGGTGGAGACCGTGCGGGTCAACGGCGAAGTAGGCGAGCCCGAACCCGAAGGGTGGCCCGGACCGCCGCTGGCCGAGCTTCTCGGCGACGACGGCTGCGGTGAGCTCACCGGCCAGCAAGCCCTGGACGTGTACGAGTACCTGGGCGAGCGCACCCACGCCGACGTCGGCTGGTTGCGTGTCACAGTGGTCGCACCGGGGCAGTCCGCGTGCGACTGACCCAGCGTCGCGAGGGAAGAACTGCCCACCGCGGAGCAAGCGGCGTGGTGCCCGGGCTGTCTAGCATCATCGGCATGCGACGATCTGCTGCTGCCGTGCTGACCGGGGCGCTCCTGGCTCTCGGTCTGAGTGCGTGCAGCCCCGGGCCCGTGGACCCGACCGCCGACTGCAGCGACAACGGTTCCCCACCACCGGGGGAGCCGGGCTCGGCGGAGGTGCTGCTCACCGCGGGTAATGCCACCGGCACCAGTCTGCTCACCACGGTGCTGTACGCCGACGGCTGGGTGCTCACGCTGGCCGGTGAGGAGGAGAGCGGGCTGAACGCGCTGGCCCCGCCGATGATGGCACCGACGCCGCCGGCGGCACGGCAGTGGCAGCCGGCGTACCTGGGTTCCTGCCAGTTGGAGGCGGTCGCCGGGCTGGCCGCCGAGGAGCTGGACGAGGACCAGCGCCTGGGCAGTCCGCAGATCACCGACCGCGCGAGCACGATCGTGACCTACTACGGCGGCGACCGGCCCACGACCGCCACGGCGTACGCGCTCGGTCAGGAGGAAGGCAGCGACCTCAGCCGGTCCGACGAAGCCGGCCGCGAGGTGCTCAAAGGGGTCATCGCGGCACTGGACGAGGCACCGGCAGAAGGTGACCTGCTCGCCGTGGAGACGGTGCAGGTGATCATCTCCGGCCCGGAGGCGGACTTGCCGACCGACTGGCCCGGCCCGTCGCGCGCGGACATGATCCCAGCCGGGGAACGGTGCGGAGAGCTCACCGGGCAGGACGCCCGGGACGTGTTCGACTACGTCGCCGGCGACGATATCGACGCACTACGCCTCGAGGTGATGCCGCCCGGGCTGCCCACCTGCACCTGAGCACCCCAGCGCCAGGGGCCGTGCCCGGGCCCGGTGCGCTCCGCCGTCGGGCGGGTGTGTTGACCGCTAGGCCTGCGGCACCCGCCGCACCGGTGCCCGCCCGGCGGGCTGGTGCACCGGCTCCACCTCGGGAACCGCCGGCACCGCCATCCGGACCGGCTCACCGGAACGCACCTGCACGGGCTCGCCGTGGTGGGTAGTGGTCAGCTCCTCGCCCTGGACCAGCTCATAGCCGGCCGTGACCTGCCCCTCGGTGCGGGTGATGTCGACCGCGAGCACTGCCTCGCCGATCCGGACATGGAACCGGAGCCGGTTCAGCTCGGCCGGCAGCCGCGGAGCGAACGTGAGGGTGCCACCGTGATCGCGCATCCCGCCGAATCCGGCCACCGCCACCAGCCAGGCACCACCCATCGCCGCGATGTGCAGGCCGTCGTCCACGTTCCCGTGCAGATCGCCCAGGTCCACCAGCGCGCCTTCGGCCCAGTAGTCGTACGCCAGCTGCAGGTGCCCGGTCTCTGCCGCGAGGATCGCCTGGGTGGTGGCCGACAGTGAGGAGTCCCGCACGGTGCGGGCCTCGTAGTAGGCGAAGTTCTTGGCCTTCTGCTCATCGGTGAACACGTCACCACGCAGGTGCATCGCCATCACCAGGTCGGCCTGCTTGATCACCTGCTTGCGGTAGATCTGGAAGTACGGGTAGTTCAGCAGCAGCGGGTAGTGCTCGGCCGCGGTGCGTGCGAAGTCCCACTCGTCCTGGGCGGTGAAGTCCTCGGACTGTGCGTGCACGCCGAGGTACTCGTCGAACGGGAGGATCATCGCATCGGCCGCGTCCCGCCAGGCCGACCGTTCCTCAGCGGTGACGCCGAGCCTGACCTCCTTCGCCGGATAGCGCCCGCAGGCCGCATCCGCCGCGCGCAGGTTGGCCTGAGCCATCGCGTTCGTGTACACGTTGTCGTCCACGATCGCGGTGTACTCGTCCGGTCCGGTGACGCCGTCGATGTGGAAGGACCCGTCGTCGTAGTGGCCCAGGCTGATCCACAGCCGCGCGGTCTCCACCAGGATCTCGGTACCGACCTCGGTGTCGAACTGGGCGTCCCCGCTGGCGGCCACGTATCGGGAGACCGCGTCGGCGATCGCCGAGTTCACATGGAACGCCGCCGTACCTGCGGGCCAGTACCCGGAGCACTCCTTGCCGGTGATCGTCCGCCACGGGAACGCCGCCCCCGCCAGGCCGAGCTCGGTGGCCCGGTCGCGCGCCTGCGGCAAAGTGTCCATCCGCCACGCCAGGTGGTCCCGGGCCGCGGAGGGGGCGGTGTAGGTGAGCATCGGCAGCGCGAACGCCTCGGCGTCCCAGAAGGTGTGTCCGTCATAGCCCACACCGCTGAGGCCCTTGGCAGCGATGCCCTGACCCTCGGAACGGGCCGCGCACTGCAGCACGTGGAACATGGACACCCGCAGCGCCTGCTGCATCCCCGGGTCGCCCTCGATCTGCACGTCAGCGCTGGACCAGAACTCGTCCAGGTAGGCACGCTGCTGCTCGAGCAGCTCGTCCCAGCCGATCAGCTTGCCGACGGCGAGGGCGGCCTCCACCTGGTCCCGCAGCGCGGGGGAGGAGCGCCGGTGGGACCAGCCGTAGGCGAGGTACTTCACCAGCCGCAGCTTCTGTCCCCGCGGGATCTGCGCGGTCACGGTGAACCGGGCCAGGTCCCCGTTCGACTCGATCGTGGTGTTCGCCCCCGGCGGCACCTCGAGCACGTGGTCCATCCCGGCAGCCATCCGCAGCTTGGACCGGCGGGTGCGGTGCATCAGCACCGCCTGCTGTCCGCGGGCCGCCGAGGCCTCCGACTTCAGCGGCCGCTCCAGCACGGCGGCATCGCGCGGGTCCGAGGACGGGCTGCCGGCCTGCTCGTTGGCGAGCAGGTCCGAGTACAGCGCCACGTAGACATCGTCCTCGAGCGGTTCCACCTCGTAGCTGATCGCGGCCAGCGACCGGTGCACCAGGGAGACCAGCCGGCGGGAGGTGACCCGGACCGGGGTGCCGCTCGGGGAGACCCACTCGGTGTACCGGTCCAGGGTGCCGCTGCGCAGGTCCAGGGTGCGCTCGTGCTCGAGCGTGTGCCCGTAGCGCAGGTCGAACGGGGAGTCGCCGACGAACAGTCGGATGATCTTCCCGTCGGTCACGTTCACCACGGTCTCGCCGGACTCCGGGAAGCCGTAACCGGCCTCGGCGTGCGGGAGCGGACGCTGCTCGTAGAACCCGTTGATGTAGGTGCCGGGCACCGCCCGGGGTTCACCCTCCTCGAGAGTGCCGCGCAGGCCGATGTGCCCGTTCGCGAGGGTGAACAGCGACTCGCTCGCTGCCAGCTCGCCCAGCGACAAGCCGTTCCGGACGAGCTTCCAGGGGTGGATCTCGTAGCCGCGGCGGTGATCGGCGTACTCGGTGGTATCGCCGCTCTCGCCGCTGGTGTGCTGACCGTGACCGTTGCTCACTGGTCCTCCTCGGGGTTGGCGGCGGGTTCGTCGTGGTCTGCCGGAGGTCCGGGCACGCCGGTCGGTGGGCGGGAGAGCGTGGAACCGACCTGGTCGCTGAGCAGGTCGGCGAGGTCGGTCACCACGACGTCCGCGCCGGCCGCCGCCAGCGCCTCGGCATGGTCGAGCCGGTCCACGCCGATCACGTACCCGAACGCTCCGGCGTGGCCGGCCTGCACCCCGGCGATCGCGTCCTCGATCACCACGGCCGCGCTCGGGTCCACACCGAGCTCTGCCGCGCCGGCCAAGAAGGTGTCCGGCGCGGGCTTACCGGGCAGGTTGTGCTCAGCGGCGACGACGCCGTCGATCCGAGCGTCGAACTCCGCCGCCAGGCCCGCGGACTCGACCACGGCCTGGCCGTTGGCGGAGGCGGTGACGATCGCCGTGGCCAGGCCCGCTTCCCGGACTGCGGCCAGGTAACGCACCGTGCCGGGGAACGTCTCCACCCCGTCCTCGGCGAGGATTCGCTGCACGTCGGCGTTCTTCCGGTTCCCGATCCCACAGATCGTGTCCGCTTCCGGCGGGTCCTGGGGGGTGCCCTCCGGGCGGCTGATCCCCCGGGACTGCAGGAAGGTGCGGACGCCGTCGTAGCGGCGGCGGCCGTCCACGTGCGCCGCGTAGTCGGCGCTGGTGAACGCGGCTTGGCCGAGGTCGGCCAGGATCGCATCGAAGGTGTGCTTCCACGCGGCGAAGTGCAGCGAGGCGGTCTGGGTGATCACGCCGTCGAGGTCGAACAGGCAAGCCCGGATCGACGGCGGAAGGCCGAGAGCGCGCAGGGCGTTCGGGGTGGGCGAGATCATGGGCACGACGCTAGTCCCCCAGGGGTGTGGGCAGTCAAAAGCGGTGCGCGCGTCGTCGATCGGTGTTGAGAGACACGATCAACACGTGTAGCATATGGTCAACACGAGTTGAACGAAGGGGTTTGGCCGATGCGAGTCATTCTGGACACCGATATGGCGATGGGCGCTCCGGGATCGGAGATCGACGACGGTTTCGCGCTCGCGCTGCTGCTTGCCGACGACGTCTTCCAGGTGGAGCTGGTCACCAGCGTGAACGGCAATATCGACGTCGAGTCCGGTACCTACCTGAGCCTGGAGCTGCTGCAGCGGCTGGGGCGGTCGGACATCCCGGTGGTGCGAGGAGCGGCTGCGCCGATGCTGGAACCAGAGAAGAGGCGCGGTGCGCCCGAAGCGGTGCGTACCGCCTTCGGACACCACCAGGCCACGCCGGGCTTCGCCGCGGCGGAGATCGCCCGGCGCGTGCTGGACGCCCCGGGTGAGATCACGATCGTGGCGATCGGACCGTTGACCAACGTGGCGCTGGCGATCGCGATGGAGCCTGCTGTGGCCCGGGCGGTCAAGGAGATCGTGGTGATGGGCGGGGTCTTCCTCGGTCACACCCAGGTCGCTGACATGCCGGGTGAGTTCAACTGGTGGGTCGACCCGCACGCGGCCCGTGCCGTGCTGCACAGCGGTGCGCCGGTCCGGCTGATCGGTCTGGATGTCACCACGCGGGTGCGGCTGACCCGTGAGCATGCCAGGCGGATGGCCGCGAGCGGGCGAGCCTTCGGGGCGTTCGCCGGTGACTGCACGATCGCGTGGTTGGACCGGTTGAGCCGGGATCGCCCGGCCGAGGTGGAAGGGGGCGACTCCTGCGCGATGCACGATCCGCTCGCCGTCGCCGCGCTCTCCCGGCCCGAGCTGCTGACCTGGCAGGACGCGCACGTCGACGTCCTCACTGCTGAACCCGCCGGCCGAGGGGTGGCCATCGCCGACCTGCAGTCCCGGACCGACGCCCCGGCCCCGAATGCCCAGATCGCCGTCGACGTCCAGGTCGAGGCCTTCATGGACTACTTCCTCGACCACATCGCCGCCTACTGAACGCCTGGCCACGCCCTGGCGGCCTCGCCCGGTCCTGACCGCCGTCGGGCTCGCGCCCTATTCCCGCCGACCCGTTCTACCCCAGCGGAACCCCCGCAATGACAGAGAAGTCAGGAAAGGACATGACCATGCGCCACCTACGCCCCGCAGCCGCCCTGATCGGCGTGGCTGCCCTCGCCCTCACCGCCGCCTGCTCCGGATCGGAGAGCTCCGGCGGGTCCGCTGAAGGCGGTGACTGGAGCATCCCCGACGAGGACCCCACGGCGACCGTGCAGGTGCTCGGCCACCAGGACACGGAGATCGTCCAGCCCGTCATCGACGCCTTCCACGAGGCCCATCCGGACATCACGATCGCCTACGAGTCGGTGCCGTTCGACCAGCTCAACTCGGTGCTGGACGCGCGGATCGGCAACCAGGACGGTAACCCGGACGTCTACTGGGCGGATCAGCCGCGGATCGCCGCGCTGTCCTCGCGTGGCTACACGGAGGACCTCACCGACCAGTTCGCCGAGCTCACCGACGCCTTCGACAGCGCTCCGCTGGAGTCGAGCTCGTTCGAGGACCGGCTCTGGTCGCTGCCGATCGCCAACTCCACCCAGCTGCTCTACTACAACGTGGACCTGCTCGAGCAGACCGGTGCCGAGCTGCCCTCTGCGAATCCGGAGGAGCGGATGACCTGGGAGGAGTTGCACGACCGCGCCCAGGAGGCCGTCGACGGTGGGGCCGAGAACGGATTCATGTTCGGTCAGATGCACCGGTACTACCAGCTCGAACCGCTGCCGGTGTCGATGGGTGGCTCCGCCGGAGGGACCGGGGAGGGCAACCTGACCCCGGACATCACCTCTGACGCCTGGGTGGACTCGATGGCCTTCTACCAGTCTCTGTTCACCGACGGGCTGCACCCCACGGGCGTCACCCCGGAGCAGTCCAGCGACGAGTTCCTCACCGGCAGCACCGCCTACATGGTGCAGGGCAACTGGCTGGTGCCCAGCCTCGCCGAAGCCGACTTCGAGTGGGGCGTGGCCGCTCATCCCTCCTTCGACGGTGGTGACCCCGTGACCCCGACCGGATCCTGGTCGCTGGCGATGAGCCCGTTCAGCGATGACAAGGAGGCAGCCGCCGTCTTCATGCGCTGGATGGCGATCGATGACGGCGGCGGTTACGCCCTGTTCCTCGAGGCACCCGAGCTGCCGGCCACCCCGGAGGGCAAGGAAGCGTACTTCGCCCGGGACATCTTCAGCTCGGATGCCGGTCAGGACGCCGCAGCGATCATCGACTACGAGACGGCGAACACCGGTGTGCCGCGGTTGCAGACCGTCGGCTATGTGGAGTTCGAGGAGATCCTCGGGCGGGCCTTCTCCGACATCGCCAACGGTGCCGATCCGGCGACCGCGCTGGCCTCGGCCACCGATGAACTGACCACCGCCTGGGCCAAGTACCAGTAGAACGAAGGCGAGCACTATGAGCGTGCAGGCTCGCGCCGCTGCCCGCACCCCGGCCACTCAGCGCCGGGGTGCGGGTGGCGGGCTCGGCCGGAGACGATCCCGGCGGCGCACCAAGGAGCTGTTCTGGGCGGCGGTGTTCCTCCTCCCGGCGCTGATCGCGATCGTCTCGATGCGGATCGCCCCGACGGTCAGCGCAGCCGTCTCGAGTCTCCACCAGGGGTTTCCTGGTGGTGTGCTGGCCGCCGAGTTCAGCGGTCTGGCGAACTACTCCGAGCTCTTCGGCAACGACATGTTCCGGGACACGGTCATCCGCACGATCGTCTTCAACGTGATCATCAACCCGTTGCAGGTAGCGATCGCGCTGATCATCTCCGTACTGCTGACCCGCAAGATCGTCGCCCCCAACCTGTGGCGGATGCTGGTGTTCGTGCCGGCCACGGTGCCGATCGTCGGCTCGTCGATCGTCTGGGGTATCGCCTTCCGCCAGGACGGCCCGATCAACGCGATCCTCGCTGCACTGGGCGGCAACCCGCAGCCGTTCCTCACCTCTCCGTCCCAGGCGATGGCCTCGATCATGGTGGTGATCTCCTGGATCGGGATCGGCTACTGGATGCTGTTCCTGGTCTCCGGGCTGCAGTCCATCCCGGACGAGTACCTGGAGGCAGCCAAGCTGGACCGTGCCGGTACGATCCGCACGTTCTTCTCCATCACCATCCCGCTGTTGAAGCGACCGCTGCTGTTCGTGCTGGTCGCCGACACGGTGGCGAACTTCGTCCTCTTCGTGCCGATCCAGATGCTCACCAACGGCGGACCGCAGAACAGCACCACGATGCAGATGTTCAACGCCTACCGGACCACCTACACCTACTCCAGCAAGAACCTCGGAGCGGCCGAGGTGATGATCCTGACGGTGATCATGCTGGCGTTCGTCGCGCTGCAGTTCCGCCTGCTCCGCGAGGACCGACCGACGAGGAGGAAGCGATGAGCGCCCCCGCATCACTGCGGCGCCGCAGCCGACTGGAGCGGCGCTCCCCGCTGCTGACCATCGGCGCGGTCCTCGTCGCGATGATCTTCATCCTGCCGGCGGTGTGGCTCCTGGTCGGTTCGCTGCGCCCCAGCGCGGAGATCTTCAGCTCGATCTCACCGCTGAGCTGGCGGATCCTCATCCCCAGCTCGGTGAGCCTGGACAACTACATCGCGTTGCTGACCGGGCCGTTCGGGCGAGCGATGGGGGTCTCGTTGCTGGTCTGCTTCCTCACCGTCGCCCTCGGACTGGTGATGAGTGCCACGGCTGCCTATGCGTTGGCGGTGCTGCAGTTTCCCGGTCGCTCGGTGGTGTTCGCGTTCGTGGTGATCAGCTTCATGGTGCCCTTCGACGCGATCGCGATCCCGCTGTCCCAGCTGTTCACCGGGTGGGGGCTGACGAACACCATCATGGGTCTGGTGCTGCCCGGGATCGGCAACGGTCTGGCGATCTTCAACCTGCGGCAGTACTTCCTGTCCATCCCGACCTCCTACCGGGAGGCGGCCACGATCGACGGGGCCTCGGAGCCTCGGGTGCTGGCCTCGGTGTACACCCCGCTGGGCGGCACCGCACTGGCGAACTCGGCGCTGCTGATCTTCCTCGGTCAGTGGACGGCCTACCTGTGGCCGCTCCTGGTGGTCTCCGAAGCGCGGCTCCAGGTGGCGCCCGTCGCACTCGCGCGCACGTTCGGGGAGCACGAGTTCAACTTCGGGGAGAACTTTGCCGGCGCAGTGCTCCTCTCACTGGTGCCGGCACTGACCATGTTCATCCTGCAGCGGTCGTTCGGCGGCCTGGCTCTGGCGACGGGAGAGAAGTGACGCGACGGTCGGGCAAGAGGGCGGCACCGGTGACGGTGATCGGCTCCGCCAATATCGACTATCTGGTGCGGGTGGAGAGTGCACCGGCACCCGGGCAGACCGTGCTCGCTGGCGGTCTGCGCAAGGCTCCGGGAGGGAAGGGCGCGAACCAGGCTGTGGCCGCGGCTCGACTCGGCGGCACCGTCGCGTTCGTCGGTTGCGTGGGCGACGATGACGACGGCGCGATGCTGCTGCGCGAGCTTCGCGCTGAAGGGGTGGACAGTGCCGACGTGGAGATCATCAGCAGGCAGAACACCGGTCTGGCGATCGTGGCGGTGGACCGGTTCGGCGAGAACTCCATCATCGTCGTGCCCGGGGCGAACTTCGCGCTCACCGAGACCCGGGTAGCGCGCGTGGTGCGGCGGGCCGAGCCGGAGTCGCTCGTGGTGCTGCAAGCAGAGATCGACCCCCGGATCATCAGGACGGCGGTGCGTACCGCTGGCCAGATCGGTGCGCGTGCGGTGCTGAACCTCGCCCCGTTCGTCCGGCTCCCGAGCGAGGTGCTCGCAGTGTGCGACCCGCTCGTGGTCAACGAGTCGGAGGCGAGCGCACTGCTCGAGGCGCCGGTGGACTCGGTGGACGCTGCCCGGAAGGGCGCGGAGAAGCTGCGTCGTGCGGTGCGGTCCGTGGTGATCACGTTGGGTGCACAGGGTGCGGTGTGGGCAGATGCCGACGGCGGAGGAACCGTGGTTGCACCCGTTCCAGCCGAGGTGGTGGACACCACGGGTGCGGGAGACGCCTTCGTGGGGGCGCTCGCCGTCCGTCTCGCCCAGGGCGCCGCACTCGCCGACGCGGTGGAGCTCGGGGTGGCGGCTGGTACGTTCGCCGTCACCCGCGAGGGGGCCCAGTCCTCCTATGCCATGGCCGCCGATCTGACCGCGGTGGGAGCCCCTCGCCTATCCGGGTGACGGCCACCGGGGGCATTGGTACGTTCAGGCCACGGGTGAGCGGGCGCGGCACGAGGGAGATGCGATGGCGGTGACACGTGCCGAGGTCGCGACCCTGGCCGGGGTGTCCCCGGCCGTGGTCTCGTACGTGATCAACGGCGGGCCGCGACCGGTGGCCGCCCAGACCCGGTTGCGGGTGGAAGCGGCGATCGACGAGCTGGGCTATCGGCCGAATCGTATTGCGGCTGCCCTGCGCGGTGGGATGACCCGGTCGATCGGGCTACTCACCCCCAGCCCGGGCAACCCGTTCTTCGCGGAGCTTTCCGAGGCGCTGGTGCGCGAGCTGTTCAACCGCGGCAACACGCTGTCCGTGGGCATCACCGACGACGACATCTCGCGGGAGCGGCTGTACCTGCGCTCCTTCGTCGACCGGCGGGTGGACGGGATCATCCTCACCTCCGCGCAGGCGGTCACCACCCTCAGGGAGCTGCAGGCACCAGAGCTCCCGGTGCTGGTGATGGACCGGGTGGGTCAGGACGATACGCCCACGTTCTCGCGGGTCCATGTGGACAATGCCCACGGCGCACGGCTGGCCACCGAACACCTGCAGGGACACGGGCATCGCGTGATCGGCTGCATCGCCGGTCCGTGGCCGGTGCCGCTGTCCGACGAGCGTGTACGCGGGTGGCGGGAGCAGCAGGAGCGTCACGGCGGAGATCATCGACCAGCGTTGGTGGAGCATGCGGAGTTCTCCGAATCCGGTGGGTACGCGGCCGCCTGGGCACTGCTGGGTCCGGACTCGCGGCGCGGTGCCTCCGGGGTGCCGATGCCGACCGCCCTGTTCGTCGCCTCCGACTCCCAGGCGCTCGGGGTGATCCTCGCCTGCCGGGACCGCGGTCTGCGAGTGCCGGAAGACATCGCGATCGTGAGCTTCGACGGCACTGCTTCCGGTCGGTACGCCAACCCACCGCTGACCAGTCTTCGCCAGCCGGTCGTGGACATGGCGCTGCTCGCCGTCGGGGCTTTGCTGGAGCGGATCCACGACCCGACGCTCGCGCCGATGCACGAGGCGCTGAAGGGAAACCTGGTGATCGGGCAGAGCTGCGGCTGTTCCACGCCGGTCGGCTAGCAGCATTCAGGATCGCCTGCCGGCCGCCGCCTGTCGATACCAACCACCCCACCGCCTCAGGCTGTGCGTGGGAGACTGAGACCGATGAGCGCGAGCAGGACCTCCGCAACCGGGGCGGAACCGGACTCGTTCGCTGACGTACGCGGCCGCTTCCCGGCGGTCGGGGAGCCGCCGCCTTCGGCGAACACGGTGCCACCTCGGGTGACCGGCCTGCACCGTGAACCGGTCCTGCGGCGTCTGGACCCGGTGGCGCAGGGCCACCTCGGACTGGTTGTCGCCCCGGCCGGTAGCGGTAAGACCACCCTGATGGCGCAGTGGGCGCGGGCCAGTGGTCTGCCGGTGGCCTGGTGCCGACTGGACTCGACCGCTGTGGCCGGGCGGCTGGTGGACTGGCTGTGGCCCGCGCTGAGCGTGCACCTGCGCGGCGACGTGGAACGACCGGCGAGCGTCGACGCGCTGGTGCGGGTGTTGCACGAGCGCTCTGGCGAGTTGCTCCTGGTGATCGACGATCTGCATGTCATCGCTGAGACGCCAGCGGCCCGGGAGCTGGAGCGGTTCGTCCTGCTCGGCCCCGGAGCCGTGAAGCTTCTCCTCGGCTCGCGCACGATGCCCGCGGTGAACTTGACCCGTTCCGAGCTGCCGCCGCTGGTGGTGCTCACCGGTGAGGACCTCCGGTTCCGCACGTGGGAGGTGGAGAAGCTCTTCCGCAACGTCTACCGTGCCCCACTACCGCCCTACGACGTTGCCGCGCTGACCCGGTACACGCAGGGGTGGGCGGCGGGTCTGCAGCTGTTCCATCTGTCCACAGTGGGGCACCAGGGCACCGCTCGGCGGCGTGCGGTGGACGCACTTGCCGGCCACTCCCGCTTCGCCCAGCACTACCTGTCCGCGCAGGTGCTCGCCACTCTGCCGGAGGCGACCCAGGACTTCCTGGTGCAGACCAGTGTGTTCGACGACCTCACCGCAGCCCGCTGCGACGAGCTGCTGGGGATCACCGGTTCGCAACGCATCCTGCGGGACCTGGTGGACCGGCAGGCACTGACCACCACGCTCGACGGCGGGGTGAGCTTTCACTACCACGACGTGCTCCGCCGTCACCTGGAGAGCGTGCTCCGCGAGGAGCTCGGTGCCCAGGCGACGCACGAGTGGTACCGCCGGGCCGCTGCCGTGCTGGAGGCGGAGCACGCGACGGTGGAGGCCCTGCGTGCCCGCGCCCGCGCCGAGGACTGGGAGGGTGTGCAGCGACTCCTGCGCGAGCACGGGCACCGGATCATGGCTGGGCCGACCTCGGCACACGGCGCAGGTACCTGGACCACCCTGCTCCCGGCCTGGCTGACCGAGACCGACCCCTGGTGTGCCCTCGCCGAGGCTCGCCGTCTGCTGAACGACGGGCAGCTGCGCGCCGCGGAGACTGTCGCCCGCCGAGCGCGGGAGCAGTTCACCGACGATGTCGGTCTGCGGGTCTGTGACCAGGTGATCGCGGATGTCTCCGTCTGGGTGGACACCACCCCACCGCCGCGGCCCACCTGGGTGCATCTGCTCCGGGCGGCGCTGCGCCGGGACCCGCTCGCTGCGGCGCGCCAGGCCCGCCGTCTCGACGGGCCGGGGGCGCGCCTCACCGAAGGGCTGGCGCTGTGGGTGGCCGGTAACCGGCGGCAGGCCTGGACGGTGCTGCGCTCGCTGGCCGCGTACGGTGACCCGGACGAACCGGCCCAGCTGGCCGCCCAGCTCGCTCTCGCCACGATCAGCGGAGTGGGCACCCGCCCGGTGGAGGACACGGTCGCCAACGTCGACGACATCGCGGCCGAAGCGAGCAGGCGTGGCTGGACCTGGATCGCGCGGATCGCCACCGGGCTGACCCTGGCGGTGGGCCCGCCCCGATCCCGGCAGGCGCTGGCCGAGGTGCTGGCCGAGCACGAGGCGCGCAGCGACCGGGTCGCCGCGGCGTTCATCTCGATGGCCGGTGCGATCGCCCAGGTGCGCGGGGACAGTGCGCGGGTGAGTGATCTGACCGCGGTGGCGCTGCGGCTGCGCGAGCTCGACTGCGGTTCGCTGGCGGTCTGGTGCGACGCGATCGCCTCGCTGAAGGCGGCGGCGCACGACCTTCCGGATGCGGAGCAGATGGCGCGGGCAGCTGAGGGCCAGGCTCGACGGGCGGCGGTGCCGGGGGCCGCCTGCTTCGCCTACTCCGCGCTCGTGCTCGTGGATACCGAGAATAGTGCGGAGGAGCTGACGCTCGCCCGGTCCACGGCGATCGAGATCGGGCTGGCGATCCGCCCCTGGGAGTGGTTCCCGGCCCACCAGTCCGCGCGCAGCAGGCCGGCCGAGCGCCCGGCGGCGGGGCTCGCGGCGGCCGAGCGCCCGCCAGCTGCCAGCGCGGCGCCCCCGTCGCCGCCGGAGCACCCACCAGCCCCGAGCACAGCCGCAGCCGCCACCACCCCGTCATCCGCCACCCCGGGTGCGGATACCCCGGGTGCGGCCACCCCGTCATCGGCCACCCCGGGTGCGGACACTCCGATGACCGACACGCCTCCGGCCGGGATCCCGGCCGCCCCCAGCCCATCATCACCGGGCACCGGCGTTCGGGTGGACCTGCGCTGCTTCGGCGGATTCGAGCTGCGCGTGCACGGCCGGTCGGTGGACCTGTCCGGGGTCCGGCCGCGGGTGCGGGCCCTGCTGAAGTTCCTCGGCATCCACGCCGGCCACCCCGTGCACCGTGAGCTGATCACCGATGCGCTCTGGGGCGAGCTGGACGCCGAGGCGGGGATGCGGTCGTTCCAGGTGAGCCTGTCCCAGTTGCGCGCCGTGCTGGAACCGGGCGTTCCGGGCCGGCGCAGCCGGATCATCCAACGGGTCGGTGAGGCCTACCGGCTCAACCTCTCCCCGGACTCCCGCAGCGATGTGTTCGAGTTCGAGGTCGCACTGGGCGAGGCGAAGGTTGCGCGCCTGGACCGGGATCAGGATCGGGTGCGGCAGGCGCTCACCCGCGCGCTCGACGCCTACCAGGGGGACCTGTTCTCGGAGGAAGGGGCCCCGGCCTGGGTGCTCACCCCACGGGAACGGCTGCGGGCTGGTGCCGCCGAGGCGGCCGCACAGCTGGCCGAGCTGGAGTTCCGCGCCGAGCGCTGGACTGCCGCGGTCTCCGCCGCCCAGCGCAGCATCGACATCGACCCCTACCGGGACGACGCGTGGCGCGCGCAGGTCGCGGCGTTGCGGCGAGCCGGTGAGCCCGCCGCCGCGCAGCGGGCGCTGCGCGCTTACCGTGCGGTGCTCGCCGAGCTCGGGGTGGACTCGGAGCTCACCGGCCTCTGAACTCCACCTCGGCGACCGCCACATGGACATCGTCGGTCGCGCCGTAGGCGCTCAAGATCGTCATCCGCACCGAGACCACGTCACTGGTCGGTAGGGAGATCGGCTGCGGTTCGCCGGTGTCCACCACGTCGACATCGTGGATCTGCTCCGCGCCGTCGGCAGTGGTCACGGTCAACCGCACCCGGCTCGGCCGTGCTTCCAGCAGCCGCGTCTCATCCGCGGTGGACGCTCCGGCGGTGAGCAGCACTGTGACCAGGCGGAACGGTTCGTCGAACTCGAACTGCAACCACTCGCCGGCACCGTCGCCGGTGGCCTCCGGGGCCCAGGACCGGTCCGAGATGCCGTCGCGCGCCAGGTCCGGGCCGCGGTCGCTCGCCGAGCTGGACGCGGTCACCTCTGCCGGGTTCACCGGATCGTTGCCGGCCACCCGGTCCAGCACCGCGTGGTACCCGGTGCCCAGCTCGTCCCGGAAGTAGTAGCCGCCACCACCGAGCAGGGCCAGGACCACTAGGAGGACCACCGTCTTCGTGGGGAACCGGCGCCGTCGCCGCCGCTTCGGCCGCGTGCCCGCCTTCGGGCCGTCCCGGCGTGCTCGACGCCGATCGCGCCAGCGGCGCCACCAGCCTCCGCGGCCCTGAGTGGGCGCATCGGCCAGGCTCGCCCCGCAGCGGCGGCAGAAGTTGCGGTGCGGTGCGTTGCCGGCACCGCAGGCCCCGCAGATCAGATCGCCGGGGGCGGGCGAAGGTTCGTCCTTCTCGGCCGGGGGGACGTGCCGGCGTGGTCGGGCGGCGGCCGGCTGAACCGGGCCGGGCACTGCCGCCGCGGGCTTGATCGCTGCCGGCTTCACGGGTTTCACCGACGGCTTCACCGGCCCAACCCCCGCCGGTGTCTCGGCGGTGGCTGCGGCGGTTGGGGGCGGTGTTCCGGTCGTCGGGGGGTGGTCGACGGCGGTTCTCGCCCGGGTCGCCCGGGTCGCCCGGGTGGCCCGGGTCGGCGGCACACTCTCGACGGCGGTGGGCGCCTCAGGGGTGTTTCGCACCTCGGTCGCCGGCTCGCCCGCCTCCTGCACCGCTGCCTGTGGCGCGGGTTCGGCCGCTTGGGCCGCCGCCGGTCGCGGCGGGGGTTCGGCCCCTTGCTCCACCGCCTGCGGCGCCGGCTCGACCACACGCTCAGGTGCGGGCTCGGCCTGGGTGAGCTCCGCCGTCGTGCTGGAGCTGGAGCTGGACGCGGCCTCGACCCCGTGCTCCTCCCACTCCAGGTAGGTGCCGCAGGCACCACAGAACAGTTCACCGTCCTCGTTCCGGACGCCGCAGTCCGGGCAGGTCTGCATCAGTCGTTCACCACCCTGATCCGGTGGGTCACATGTGCCGGCTTCACCGCGGTCACCACAGCGTCCAACCGGGCTTCGTCCACGCTCGTCCCGGGCCTCGGGCGCACCCGCACGGTCACTCGCGGCCGGGCCCGGCCCGGCAGGGCACCGCCGGGCTCCGCCGACCAGGCGTCTCCGCCGTTATCGGTCACCTCGACCTCGCCGTCGACGATGAGCCGCACTGCCCCGGCGATCCCGGCCGTCGTACCCCGCCGGGCATGCACCGCCACCGCACCGGCCACGATCTCCCGGCGCTGGGCCACCGTCCACGCCTCATCCACCTCGATACCCACCCACTGTGCGAGCCAGTCGAGAAAGTCCGTTGGCGCGAGCTGAGGGTCCACATAGGCGCCCAACCCGTCCAGGCTGAGGAAGAGCGGCGCCAACGCTTCGTCGAAGGCACCCAGGAACCTGCCCAGGAATTCGTCCTCCTGGAGCACACCCGGTAACCGGTGCGCCACCGGGAACGGGCTCGGCTGCCCGGCGATCACGCCTCGCATCATCGGCCCCCACTCGCGCGCACCTGGTGCTGGTAGGAGAACACCAGCCCGCTCGCATCCAGATCGATCCGGGTGGTCGGCTCGCCGCGTTTGCCGGTGATCGGGTCGGCGCCGAACAGCTTCACGTCCTCGATCAGCTCCAGACCGGTCAGTTGCTGCAGCACGGCATAGACCTCACCGGCCTGCACCGGCCGGCCGAACGGCCACCCGGCGTGATCCGGCCCGCCAGTGATCGGGTCGAAGTAGGCGTTCAGCGCCTCCAGTGCCTGCCGTTCCAGCCGCTCCGCATTCGCGCGCGGGCGGGCCGCGATCCGGGCCACCACGGTCACTCCTTGGTAGAACGGTGGCTCCACCAGCAGCCGGGCACCCACCGGGCGGCGCTCGCCCAAGTAGTCGGTGATCCGCTGCAGCGCCCGCTCCGAGGGCAGCAGGTCCTCCAGCCGCAGCCGGCCCTGGGCATCCGGCACCGCCGCCGGCACTACCAGCAGTCGCACCCCGCCAGCGTCCTCAGCGGACTCGGCCACCACGCACCGGACCCGGGCGATCCCGGGCGCCGCCCGGCGGGCGAGCACCTCGTAGTCCTCGGCGGTGACCGCCCGATCCAGTGTGCGCAGCGAGATCGGCCCACGCACCATTGCCTGCTGCACCGTCTCCGGGGCGCGCCCGCCCAGACCGGCCCGTCGGTTCACCACCCGGTCCACCAACGGCACCAGGTCGCGCATCACCGTCACCGCCCGCGGTGCCACGTTTCCCGCCGGGCCACCGCCGGTGCGGTAGGAGCGCACCCGCAGGGGCGCGCCCTTGGCCGGGACGGCGCCGTAGTGACGCAGCGTGCCGTCGGCCTCTCGTACCGCCGGCGGCAGGATGAGCTGCCCGATGGCCCGGTCCAGCCGGAACACCGTGGACTCCGGCAGGCTGCCGGCGAACGTCTCCACCTCCGCCCACTCCTGCCAGCCGTCACCGGCGGCCACCTCCAGCACCACCCCGCCGCCGGCGGTCACCGGGGCGTGCGCCAGCGTGAACACCTGCCCCGGGATGCCCTCGGAGAGGCCGAGCACCTCCTCGGTCACCGTGCGGGCGTGCCCGGCGGGCACTGTGCCGCCCATGGTCACCGCGCTGGCCGCACTGATCGTGGGGGAGACGCTGTAGAACGGGAACCCGGGGTCCGGCTCGATCACCCGGCAGCGCAACCAACCGGCCCGCTCGCCGCCGATCACCGAGGTCTCATGCTCGGCCGGCACGTGCAGCAGCACGTCCCCGGACCGGTTCAGCCCACCGGTGCCGTCATGGTCCACCTCACAACTGCGCCAGCCACCCTCGCACCACGCCTCCCAGCGCAGTGGGGGGAACCGTGGGTCCACGCCCTTGCCCTCCACCTGGGCATCCACGTGCACCGAGACGATGCAGCCCGGTGCGGCATCGTCCAGCCCCACCAGGAGGACGTCTCCGGGGACCGGTGGGCTGGTGAACACCGAGAACCGGTCGCCATCGCGGAGCTCGCTGCTGCGGTTGGTGGGCTCGCCGTCGTTCGGTTGGGTGGCGGTGTGCAGGAGCTCACGTGGCGGCACCACCAGATCCCGGAGCGTGGCAAAGACCACCGGGTCCTCATCCTCCTGCCGCGGTGTGCACGCCTGCGAGGCGGCAGGTACCCGCACGTCCTCGGTCTGCGGGGCGGACAGCCAGTAGGTCAGGTCCACCGTGGCGGCAGCCGGCGGGTGCAACTGCACCCCGATCAGGTCGAGGAAGGTGAGGTAGAGCCGGTCCGGTACCCGGTTCAGCCGGTAGGACAGCTCGTCCACCATGTGCGCGAACGTCTCCACCAAGGTCACCCCCGGGTCGGAGACGTTGTGGTCGCTCCATTCCGGGCAGGACACCTGGATGTAGCGCTTGGCGTCATCCACCAGGTCCTGGAAGCGCCGGTCGTCGAGGTCGGGGGCGGGCAGCATCGTCAGGCGCCTTCCTCATGGTCGGGGATCACGTAGAACGGGAAGACGAGGTTGCGCGGGTCGTTGGTGCCGCGCACCGCGTAGGCGATGTCGATGTAGAGCAGACCGGAGTCCACCTCGTCGAAGCGCACGGTGACTGACGCGAGCTCGATCCGTGGCTCCCAGCGCTCCAGGGCCACCCGTACCGCGTAGGCGATGTCCCCGGCGGTGGAGGCATCCGCCGGGGCGAACACGAAGTGGTGCACCCCGCAGCCGAACTCCGGGCGCATCGGCCGCTCGCCCGGTGCAGTGGCCAGGATCAGCCGGATGCTCTGCTCGATCTCGGCATCGCCCGAGGCCAGGGCGATCGCTCCGGTGCGGCTGGTGCGCACCGGGAACGTCCAGCCCGAGCCGATGAAGTCCGAGGTCATCTGCCGCTCCCTAGTTGATGTTCACGAGGGCACCGCGCACGGTGACCGGGCCGGAGGCGCTGAGCTCGGCCGAGGCCTTGCCCTTGACCGCAGCCACCGTCCCCTCGAGGGACGTGTTGCCGTTCGCCTTGACACTCGCGTTCGCCTGCGCCTCCAGGTCCGCATTCGCCTTCGCGGCGATCTTCACGTTCACCCCGCTGAGCTTCAGGTCGCCCTTCGCGGCGATCTCCACGATCTGGCCCGCGAGCTTGATGTCCTGCTGTGCGGTGATGCTGATCGTTCCTTGGGAGACGATCTCGATCCCGCCGTTGGGCGCCTGGATGATGGTGATCCGCTCTTTACTGTCCTTGTTGCGCACGTTCAGCTTCGTGCCGGAAGCGTCCTCGAGCACCTCCACGCTCATCCCGGTGCGGGAGGTGAAGCCGCGGCGGATCACCTTCCCGGTGCCGTCGACGTGCTTGTCGAACGCCGGTAGGGGTAGGTCCTTGCCGTTGTAGACGCCGCCGAGCACGTACGGCGACTCCACCCCGGTACCACCGAATGCCACCAGCACCTCGTCGCCCACCTCCGGCAGCAGCACCGTGCCGCGCTGTGCCCCCGCACCGGCCTGCACCACCCGGGCCCACCAGCTCTCCTCCGTGTCGGACAGGGTGGGCAGCTTGACCTTGACCCGGCCCTGGTTGTCCGGATCCTTGAGGTTGGTGACCAGGGCGGGCAGCATCCCGCGGGTGGCCGGCGGCGCCTCGATCGCTCCGGTCAGCACGCCGTAGGTGGACCGGTCTGCGGCATGTGCCACGGTGACGTCCGTGACGTAGCCGGCGATCTCGTCGAAGCGGTGCCGAGCGGCGGAGAGCACGTACTTCCCGTCGAACTTCTTGCCTGCACCCTTGAGGGTGATTGCCGCGCCGGCGAACAGCTTTGCGTTCCCGCGCACCCGCGCCTCCAGCTCGGCGAACCCGCCCGCCCTGCTGCTCATCCGGGACTCGGCCCGTGCTTGGACCGCCTTGATCTCGCTCTGCCCGGGAACGCTGATCACCTCGGCCGCTCGACCCGTGGCGAGTGCCTTCGGGGTGCTGGTCACCGAGGCGCTGGTGGAGTCGGCCTTGGCCGAGTGTGCGATGAACCGCTTCTCCTTCGGGCTCCAGCCGCGGGCCTCCACCTCCGGCACCTGGTCGCTGTCGGTGATGGTGCTGCGCAGGCCGAGCACCTGCTTGCCCACCTCGAGCACCAGCGGGTCGCCGGTGGCGGTGGGGGCACTCGAGGCCGTCGGCGGCATGCGCAGCTCGAGCGTCTTGCCCTTCATCGAGAGCACCGCACCGTGAGCGGTGGCCAGCCGGGTGACGAACTCCCAGTCGCTCACAGCGTCCTGGGTCAGCTGCGGATAGACCGGCCCGATCTGGTCCACCTGGCAGGCCACACCCACGCTCCCGGCGATCGCGTTGACGATGTCGGAGATCTTCTGGTCCACGTAGGTGGCCATCTTCGCCCCGCCCTGCAGCTTGCGCCGCGCGTCCAGGGCGCGCACCACGGTCGTCATGCCGCGGGAGTCGATCTCCCGCTCCAGGCTGGTGACGGTCGCCTCGATCAACGGTTCCGGGGTGCCGGGCGTGGAGGAGCCCACGGCGAGCGAGACAGGCTTCCCGATCGCCAGGCCCGCACCCTCCAGCACGGCGTCCTCCGGATCGGAGAAGCGCAGCACCAGCAGACCCGGCAGGTGCACCGAGTCGTCCACGTACACCTCGGTGATCAGCGCGGCCCACTGCTCCGGCAGCACGGCACCGGCAACCTTGACCACCGGCCGGTAGAAGTACACCTCATCTGTGGGCACCGGCCACCTCCTGACCGCCGACGGCCGGCATCAGTTCCTCAGCGGCCGGCAGCAGCACCGTGCTGCCCACCCGGACCCGGAACGGGTCGTCGATGTCGTTCGCGCGGGCCACCTCCCGCCACAGCGACGCCGTCCCGTACTCGGCGTAGGCCAGCGCGGCGAGCGTGTCCCCCTCGGCCACCCGGTGCGCCCGCCGCGGCACCAGCCCGCCGGAGGTGGGATTCTGCCGCGGTGTGTTCCCGGAGAGCTCCGCCAGGGTGAGGGTCACCACCGCCCGGATCGGCAGCCCGCCGGAGCTGAACAGCGTGTACCGGGCGCTCACCTGGGATACGTAAGCGAGGAAGCTGGTGATCCCGCCCCAGCGGAACATCACCCAGGGTGGAGAGTCCCGGTTCTGGGAGTGGGAGGAGGAGGTCGGCACACAGCAGCCGAGCAGCACCTCCACCTTGGTCACCACCGAGTTGTCCTGGGTGTCCGAGGCATCCAGGAACAGCTCCAGGTCCAGCTGGGAGGGTTCGGGACCCTGGTACTGGGGAGGGCCGCTGCTCTCGTTGCCGGTGCCGGTGGCACGTGCCCACCGGGCTGCCTTGCCGAGGGTGAGCTCGGTGGGGTTGAACTGGAAGTCCACCCGGTCCAGCTCGCCGCCGGGCTGGGCGAGGGAGCCGTCCCGGGACGGCTCGTACAGCTGCAGGTAGGCCTTTTCGAACTTGGTAGGGGAGCGGCTCCCGCCGGTGGATGTGCTGACACTGTCGATCGCGACTGGCATGGCGGACCTCCTCAGGCTCCCTGTGCGGCGATGAACCCGTGGTGGGCGACCTCGAGAGTCTCGGTGGCCACCTGCGGGGAGTCCGGGTTGAACGAGGGACCGGACCAGCGCACCGGGACCACCCCGTCCAGCCCCCAGTCGGCGACCACGGTGGCGTCCGGCGTCATCGCCTTGATCGTGGCGGTGCTGCGGGAGTAGCCCTGGGTGATCGAGGTGATCCACTCGCCGATCTTGCTGGTGTCCCGGCCCAGTGGGCGGGTGAGCTTGACCGTGGGGTAGCTGATCCGGCTCGGGAATTGCCAGGTGAACTGGTTGTTGCCGCCTTCCTGCCGGGTCTCCAGCACCACTTCGCAGCCGAGGCCCTCGCAGCTGGAGAACGCGCCCAGGTTGCGGTTGTCGATGCTGACCACGAAGTGCAGCGTGACGGCGGTGTCGACCTCGGCCAGCATGGCCTACCTCCAGTCTCCGCGGCGGCCGCGGCGCTCACGGTCGAGCAGGAGCTCGTTGCGGATCCGGCGCATCATCGGGTCCAGCAGCTGCTGGGCCAGGGTGTCCAGCTCGGGCGGGCTGAGCTTCGCCGGAGTGGCAGATGGTGCTGGTTCCGTCGGCGGTACCGGCCCTGCGGAAGCTGCGGTCGGCGCGCTCGGTGGGTCGTCCGGCGGCGGTGGCTCCTGCGGGAGCGGGGTGGCCGGGCGTTGCGGGAGTGAGGTGGCCGGGCGTTGTGGGACCGGCGGTAGCGGGCGGTGGTTGCCGAGGAACCCGCGGGCGCGTTGGGCCACGACCGTCAGCGGCGGCCCGGTGTCGGGCGCGGGGTCGCTCGGGCTCTGGACCGGTGGCCTGGTCGGCGCGAGCAGCGCCGAGCCGGGGTGCTCGGTCGTCGCTGCGCTGAGCGAGCGTGCCAGGCTGGCGGTCGGGGTGCGTGGTGCAGGTGTCGACGACGGCGTTCCCCGGCTGGGCAGCCTCGGCGCACCGGGCGGCGAGGGGCGCGTGAGGTGGGAGGCACCCCGTGGTGAGGTGGCGAAGGCCGCGGTCAGTCGTCCGGCTGGCGGGCGCGCGGTACCCAGCAGTGCCGTGGTGGTGCCGTGCCGCTGGAGGGCAGCCGATGACGGGAGTAGCTCGGGACCGGACTCGAAGGTGCCGACCGGTAGCCCGAGATCGGGGCTGGTGCGGCCGGCAGGCGAGAGGCTGGCGGTCGGGAGGCTGGCGGTGGGCACAGCGGAGGGATCTGTCCCAGTGGCGGGCGCCCTGGACGGACGTGGCCCAACGGCGGGCGCGCTGGATGGACGTGACCCGGTGGCGGGTGCGCTGAATGGACGTGACCCGGTGGCGGGTGCGCTGGATGGACGTGACCCGACGGCTGGCCCGGTGGTCCCACGGCCGGCAGCGGAGGTCGCTCGTCCCGTTGCCACCGAGCCGGGTATCACTGAGCGTGATATCGGCGTCGACGCACCCCCGCGGGGGGCCGAGGGGGGCAGGGAACCCGTGGAGGTGGCGGGTGGCGCGGGCAGGGTGGGGGAGGTGGCCGTAGGGCCCGGGGACGGGACAGGCCCCCCGGGCCGTGGGAGAGGGCGAAGTGCCTCGGCCGCCTCCCCTGGCGGTCGCCGTTCGGCGGGAGGCTCGGGGTCAGCCGGCCCGGTGAGGCGAGCGGCAGTGGCGGCGCTCTGGGTAGCCCTGACCTGGAGTGCGGGGGTGTCGGCGGTGGGGCCGGTCGACAGAGTCGAAGAAGGACTCCCGGAATCCGCGCCGATGCCGAGAAGTGGCGCCGAGGAGGGTGAGGTTGGGCCGACGGCGCCAGTGGTGGTTGTGGCATGGGCAGGGTCCGGTCCGCTGGTTTCGGTCCCAGGAAGGGTCGACCGTTGTACCGGCATGTCGGCCGGCCGCGAGGGCACTGAAGCCACCGTTGAGGTGGATGGTGCCGGCGTGCTCTCGGTCTGCTGGTCGGCAAGAAGAGGAGCGTGTCTCGGGTCGGTGGTCGGGACGGCCCAGTCGGCAGTGCCGGAGCCGTCGGGCGCAGGCGGTTCGCCGACCGACGCTGCGCTTCCTGCGCGCCCCCCGCTTCCCGCTTTCCCTGCAGTCTCCGCGTTCCCGGTGCTCCTGGTGCTCCCGGTACTCCCCGTCTCGCCGGCCCCTCTCGTCTCGCCGGCCCCACCCGGCGGTGCGCCGGCTGCCCCGTCCGCGCTTGGGGACGCCGGCGGCACCGGGAGGGACGGCGCACGGTCCAGGGGGCCCGCCGCACCCGCCGCACCCGCCGCACCCGCCGCACCCGCCGCACCCGCCGCACCCGCCGCACCCGCCGCACCCGCCGTGTTCCTGGGGGCGCGATCGACCGGACGAGAGCTTGATGGTGAGCCGGTCGATCGGGGTGGGAGCGGCAGGGCGTGATGGGGCTGGCGCTGCACGATCGGCGCGCCCGGTCCTGGTCTGGTCTGGTGCGGTCCGGCCGACGAGAGCCGGGGCGACGGCTCCTGGTGCAGGTGGCCGGCCGGAGTCGTGGGCCCGCTTCCCGGAGCGGTCCCGGTTCCCCGGGCGACGCCGGGAACGACAGCACGGGGATCGTCAGGAGTGGCCGGGGCGGGGTGCACTGGGGTGAGCGCCGATGGTGCCGGGTCCAAGGGCGCCGAGCTGGCGGGCGGCGGGCCTGGCTGTGCGGCAGACGGGGAGGTGGCCGGGGCTGGTGGTGCGGATGCGGGCGTGCTCGATGGCTGCACTGACGTGCCGGGCTGCACCGATGGCCCTGTCTGTCCCGGCGGAATCCCAGACGCCGCTGAGGTGGGACCACCCGCCCTACGCGGCACCCCCTGCACTGACTGTCCCGGTGGCAGCGGGGCGCCAAGGCCGAGCCGGCGTTGAGCGGGCGCGGTCGACGGTCGCGGAGCACCGGAAGCCCCCACAGACCCTCCGCTACCCGGGCGCCCGCTACCCGGGCGCCCGCCATCTGCTCGCCCATTATCCGCGCGCCCGGACTCCCGGCCTCCGGTGCCCCTGGAGGGGCCCGGCCCTGCCCGACCGGCGCCCGGGGCTGGCTGCGGGCCCGCGCCCCACGTGCCGGAGTCACCGCCGCCGGACGCGCCCGGCGGCCGCGGGAGCGAGACCTCGGTGTACCCGGACAGCGCTGCCCGCTGGGCGATGACGTCGGCGATCGGTGCGGAGTACGACGTCACCGGTGCCGGTATCGGCTCCGCCGCTGGAGTTGCGGATGCGGCTGCTGGTGCGGAAGAGATACTCGGCCCGAGCACGGGCCTGGCACCTTCTTCCGGTGTGGCCGCCACGGAAGCACCGGACCCGGTCTGCCCCGGTCCGGATGAGGGTCGCAGCGCCGCCAGGTCCTCGGCACCACCGAGGGCGTAGTGCACCCCCGGGAGCTCAGTCGGCGTGGGCGCGGTGAGTAATGGGCCCCGGGCGTGGCGAGCCACGGCCACGGTGGCAGGCGCCGCCGACTGGGCCACTGGGCCTCCGCCGTCGGCATCGGCCACAGCGGAAGGCGCCGCCGACTGGGCCACTGGGCCTCCGCCGTCGCCATCGGCCACAGCGGAAGGCGCCGCCGACTGGGCCACTGGGCCTCCGCCGTCGCCATCGACCACACCGGAAGGCGCCGCCGACGAGACCAGGTGACCCAGCTGCCCCAGCAGCGGCATCGACCGGCCGGTCACCGTCCAGCCGGCGCCGGATGCGGTGTGCACCGGCTCGGCAGCGCTGAGCACGCGCTGCAGCGGCGGAAAATGTGCCCACCCCATCGGCTCCGGCCCACGCACAGGTGCAGCGACCGGAGGCGCGGAGGCGGCCTCCCGTACCGGGCGTCGCTGCCAGGGCCAGCGCATCAGACCTCCTGTGTCATCCGCCGGTTGATCGTGGCGATCTCGTGCACATAGCGCTGCCGCTGCCCGTGCTCCAGATCGAGAATGTCGTGCTGCGGCCAGTGGAAGTGATAGGCGACGTACGCGACCTCCTCGTACAGCCGCTCGGGTGCGTACGTCACGATTCCCCCAGGCGACCGTCCGAGAGGTCGAGGGTGAACCGGTGCGCACAGGACGGGCAGCTGACCGCCGCCCTGGCGTGCCCTTCGGTGTTCACCCGCCGGTACAGGTCCTGCAGGAAGGCGACGTCCGAGGCGAACATGTTCTCCACCACTGAGGAGGTCACCGAACCCAAGGTGCCGAGCGAGGTGATCACCCGGCCGAGCAGCACCACCGTCGTGTAGGCCGCGTTCTCCTGCACCCGCGCGTCATACAGCGGGAGCAGCTCGTCGCGCGCGGTGGCCAGGCGCATCGTGCCCTCGCGGTGCACGGTGCCGTGGGAGTCCTGGTAGCCGCGCGGGAGCACGAAGTCGAACTCGGTGCGCAGTTCGGCCTGCGCCGCCGACGCGCCCGGCTGCTCGGTGGCAGCGGGCGCGTCGACCAGCTCTGGGGGTGAGCCGCGTCGCATCAGCTGAACTCCATCTCATCCCAGCAGACCGTGAACGCCTCCACCAGCGGGTCGGTCGAGCCGGCCTTCAGCGAGCCGGAGACCTCCACGTCCTTCACCCAGCAGTTCCGATAGGAGAGCTTCTTCACCACGGAGTTGTCCGAGGCGAAGATCGTCACCTCGGCCGTCTTCCGAGAGGCGCCGAGCTTGCCGCCCATCACCTCCTTGAGCCAGTCGGTGACGGTCTTCGAGTCGGTCAGGCCACGCTTGACCGTGAACTCGCCGGGCTTCTGCCGGCCCATCATCTGCCGGGTGATGAATTTCCCGTCCTTGGCCTGCTGCTGGAAGGCGATCTTGTCCACCTCCGTCTTCAGCCCGGCGACCTCCATCACGTACGGCACCTCGACGCCGTCGATCGTCACGCTGAACCCGTAGCCCGCGGCGAGGTCCATGGCATCTGGCAATGGCATTGTCTGTTCACATCCTTCTCATCGCTGGGGGGACTACTCGTTCACCAGGCTGGCGCCGCCGGAGAACTGCGCGAGCTGGAAGATCACGAACTCGGCCGGCTTCACCGGGGCGACACCGATCTGGCAGGTGACCTGTCCGGCGTCGATGGCTTCGGCCGGGTTCGTCTCCCGGTCGCACTTGACGTAGAACGCCTCGTCCGGGGTGAGCCCGAACAGGGCGCCTTTGCGCCACTCGTTCACCAGGAACGCGGCGATGGTGCGCCGGATCCGGGACCAGAGGGCGTCGTCGTTCGGCTCGAACACCACCCACTGGGTGCCGATCAGGATCGACTCCTCCAGGTAGTTGAACAGCCGCCGCACGTTCAAGTACCGCCAGGCCGGGTCGCTGGACAGGGTGCGGGCACCCCAGACCCGGATGCCGCGGCCGGGGAAGGAGCGCACGCAGTTGATCCCCACCGGGTTCAGCAGGTCCTGCTCGGCGCGGGTGATCGAGGTCTGCAGCGAGATCGCTCCGCGGACCACCTCGTTCGCCGGCGCCTTGTGCACCCCGCGGGTGTCGTCGTTACGGGCCCAGACCCCGGCCATGTGACCGGACGGCGGCACAAAGCTGTTGGTGCCGCTGGCCGGGTCGAACACCTTGACGTAGGGCCAGTACAGGGCGGCGTACTTGGAGTCATACCCGGCGCCGTCCACCCGCCACTCCTTGATCTGCTGGGCGTTCAGGTTCGGTGGCGGGTCCAGGATCGCCATCCGGTCGCCCATCAGCTCGCAGTGCGCGATCATCGCCAGCTGCACGGCCTGGACCGCCTCCAGATCGATCGCGCCCTGCTCGTAGGCGGCCATCAGATCTGGCACGGCGAGCATGGTGACGTCCTCGATGGCCTCCAGGCCGGCGAAGCCTGTGCGCGCGGCCGCATCACCGACGTAGTCGTCGGTGCCCAGGCGCTGCGGGGTGGGCGGCTCACGCTCCGGTTCGGGGGCGACCAGCTCCACCTCGCCCTTGGTCGGCTTCATCACCGCGCTGCCCTGGGCTACCTGCTCGATGGTGATCAGCTTGGACTCCTGGCTCACCTTGGTGGCGACGTTGTCCGCGCCCTTCTTGGTGGTGACACCGTCGAAGGTCTCGGTCGGCTTACCGTCCACCTTGATCACCAGCTTGAACTTGTCCTCGCTGGCCTTCTCCTCCTCAGTGGCCTCCACGGCAACCGAGATCTTCTTGGTGCCCGAGTCCTTGGCGGTGATTGCGAACCCGGAGACGTCGGCCTTGGCGGGACCGGAGATCTGTTTGCGGGAGCCGCGCTTGCCCTCACCGTTCTCGGCGCCGATCCGCACGATGTAGCTGTTGCCGCCACCGTTCAGGAAGTAGCCGTAGACGGCGTGGGCCAAGTAGGACTGCGGGACGAACTCGCCGAAGGTCTCGGCGAACTGGGTCCAGTTCGACACCAGGGTGGGCGTGTTCACGGGTCCCTTCTCCGCGAGCCCGACGAATGCTGCGACGGCAGTGCCCACGCCTTCGATCGGGCGACTTCCCGCCTCGACCTCCTCGACGTAGACACCGGGCGATAGGTAGGTCGGCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP042828|349907:383260|353346_354204_+|WP_147915518.1|DBSCAN-SWA
MGRKLGQLRARARIVGAGVAAALVATTLAGCSLFGLDEEPALECPGESAPTSAPGEARVMLTIAEGASAWDLTWVVYDDGSVALLDGQQQAETGTNALAAAGPLPQYAGGPYTEQPGSWSSGYLLPCALAELRQRADDALFGSPEYGRVSITDNPWTYVSYDNGASRASVEVYAFDTGYTEGLEWSERRARERLAAVTHFLEANLVRTGETIPVSRVQVDGAGEVGEGFEWPGPAPAELLGEQGCGVLTEDPATAVYEFAQEPGLGEASSELTVRALPPGVSGCR
>NZ_CP042828|349907:383260|355352_356066_+|WP_147915521.1|DBSCAN-SWA
MTACSPSPIDPTEDCTDAGSQPAGEPGSAEVLLTSSGYVLYADGWMVITAEDEASAANAMRVPLMAPAPPAGDRWQPAYLGSCQLEAVDALAAEELVEGDLGDPIVTDASTTTITYYGGEEPVSSSAYALGSESSDLSRADQQGREVLKALIAALDEATVTGDVLPVETVRVNGEVGEPEPEGWPGPPLAELLGDDGCGELTGQQALDVYEYLGERTHADVGWLRVTVVAPGQSACD
>NZ_CP042828|349907:383260|364654_365572_+|WP_147919265.1|DBSCAN-SWA
MTVIGSANIDYLVRVESAPAPGQTVLAGGLRKAPGGKGANQAVAAARLGGTVAFVGCVGDDDDGAMLLRELRAEGVDSADVEIISRQNTGLAIVAVDRFGENSIIVVPGANFALTETRVARVVRRAEPESLVVLQAEIDPRIIRTAVRTAGQIGARAVLNLAPFVRLPSEVLAVCDPLVVNESEASALLEAPVDSVDAARKGAEKLRRAVRSVVITLGAQGAVWADADGGGTVVAPVPAEVVDTTGAGDAFVGALAVRLAQGAALADAVELGVAAGTFAVTREGAQSSYAMAADLTAVGAPRLSG
>NZ_CP042828|349907:383260|359415_360234_-|WP_168211924.1|DBSCAN-SWA
MRALGLPPSIRACLFDLDGVITQTASLHFAAWKHTFDAILADLGQAAFTSADYAAHVDGRRRYDGVRTFLQSRGISRPEGTPQDPPEADTICGIGNRKNADVQRILAEDGVETFPGTVRYLAAVREAGLATAIVTASANGQAVVESAGLAAEFDARIDGVVAAEHNLPGKPAPDTFLAGAAELGVDPSAAVVIEDAIAGVQAGHAGAFGYVIGVDRLDHAEALAAAGADVVVTDLADLLSDQVGSTLSRPPTGVPGPPADHDEPAANPEEDQ
>NZ_CP042828|349907:383260|374227_376045_-|WP_147915533.1|DBSCAN-SWA
MPTDEVYFYRPVVKVAGAVLPEQWAALITEVYVDDSVHLPGLLVLRFSDPEDAVLEGAGLAIGKPVSLAVGSSTPGTPEPLIEATVTSLEREIDSRGMTTVVRALDARRKLQGGAKMATYVDQKISDIVNAIAGSVGVACQVDQIGPVYPQLTQDAVSDWEFVTRLATAHGAVLSMKGKTLELRMPPTASSAPTATGDPLVLEVGKQVLGLRSTITDSDQVPEVEARGWSPKEKRFIAHSAKADSTSASVTSTPKALATGRAAEVISVPGQSEIKAVQARAESRMSSRAGGFAELEARVRGNAKLFAGAAITLKGAGKKFDGKYVLSAARHRFDEIAGYVTDVTVAHAADRSTYGVLTGAIEAPPATRGMLPALVTNLKDPDNQGRVKVKLPTLSDTEESWWARVVQAGAGAQRGTVLLPEVGDEVLVAFGGTGVESPYVLGGVYNGKDLPLPAFDKHVDGTGKVIRRGFTSRTGMSVEVLEDASGTKLNVRNKDSKERITIIQAPNGGIEIVSQGTISITAQQDIKLAGQIVEIAAKGDLKLSGVNVKIAAKANADLEAQANASVKANGNTSLEGTVAAVKGKASAELSASGPVTVRGALVNIN
>NZ_CP042828|349907:383260|349907_350627_+|WP_147919263.1|protease|DBSCAN-SWA
MLPGWGHGLLVVSLAAAWWRDRELGKDLTLIGLGVAIVSTTSVEADVHWDRFFTIGIVLALAVATPLLVDRFVYRRRAIRFPWRTGKKWSPIERSYLVLVPLLGWLILPFYFITSGAYLNWPYITDGSMLARFFVGVNFVGTWDELFFICTCFALLRRHFPVWAANLLQATIFVSFLWELGYREWGPFLTAPFALLQGWIFTKTGSLTYVLIVHLLFDVMVFLAIVHAHNPGWIPIFLV
>NZ_CP042828|349907:383260|356998_359419_-|WP_147915523.1|DBSCAN-SWA
MSNGHGQHTSGESGDTTEYADHRRGYEIHPWKLVRNGLSLGELAASESLFTLANGHIGLRGTLEEGEPRAVPGTYINGFYEQRPLPHAEAGYGFPESGETVVNVTDGKIIRLFVGDSPFDLRYGHTLEHERTLDLRSGTLDRYTEWVSPSGTPVRVTSRRLVSLVHRSLAAISYEVEPLEDDVYVALYSDLLANEQAGSPSSDPRDAAVLERPLKSEASAARGQQAVLMHRTRRSKLRMAAGMDHVLEVPPGANTTIESNGDLARFTVTAQIPRGQKLRLVKYLAYGWSHRRSSPALRDQVEAALAVGKLIGWDELLEQQRAYLDEFWSSADVQIEGDPGMQQALRVSMFHVLQCAARSEGQGIAAKGLSGVGYDGHTFWDAEAFALPMLTYTAPSAARDHLAWRMDTLPQARDRATELGLAGAAFPWRTITGKECSGYWPAGTAAFHVNSAIADAVSRYVAASGDAQFDTEVGTEILVETARLWISLGHYDDGSFHIDGVTGPDEYTAIVDDNVYTNAMAQANLRAADAACGRYPAKEVRLGVTAEERSAWRDAADAMILPFDEYLGVHAQSEDFTAQDEWDFARTAAEHYPLLLNYPYFQIYRKQVIKQADLVMAMHLRGDVFTDEQKAKNFAYYEARTVRDSSLSATTQAILAAETGHLQLAYDYWAEGALVDLGDLHGNVDDGLHIAAMGGAWLVAVAGFGGMRDHGGTLTFAPRLPAELNRLRFHVRIGEAVLAVDITRTEGQVTAGYELVQGEELTTTHHGEPVQVRSGEPVRMAVPAVPEVEPVHQPAGRAPVRRVPQA
>NZ_CP042828|349907:383260|376031_376811_-|WP_147915534.1|DBSCAN-SWA
MPVAIDSVSTSTGGSRSPTKFEKAYLQLYEPSRDGSLAQPGGELDRVDFQFNPTELTLGKAARWARATGTGNESSGPPQYQGPEPSQLDLELFLDASDTQDNSVVTKVEVLLGCCVPTSSSHSQNRDSPPWVMFRWGGITSFLAYVSQVSARYTLFSSGGLPIRAVVTLTLAELSGNTPRQNPTSGGLVPRRAHRVAEGDTLAALAYAEYGTASLWREVARANDIDDPFRVRVGSTVLLPAAEELMPAVGGQEVAGAHR
>NZ_CP042828|349907:383260|366764_369992_+|WP_147915529.1|DBSCAN-SWA
MSASRTSATGAEPDSFADVRGRFPAVGEPPPSANTVPPRVTGLHREPVLRRLDPVAQGHLGLVVAPAGSGKTTLMAQWARASGLPVAWCRLDSTAVAGRLVDWLWPALSVHLRGDVERPASVDALVRVLHERSGELLLVIDDLHVIAETPAARELERFVLLGPGAVKLLLGSRTMPAVNLTRSELPPLVVLTGEDLRFRTWEVEKLFRNVYRAPLPPYDVAALTRYTQGWAAGLQLFHLSTVGHQGTARRRAVDALAGHSRFAQHYLSAQVLATLPEATQDFLVQTSVFDDLTAARCDELLGITGSQRILRDLVDRQALTTTLDGGVSFHYHDVLRRHLESVLREELGAQATHEWYRRAAAVLEAEHATVEALRARARAEDWEGVQRLLREHGHRIMAGPTSAHGAGTWTTLLPAWLTETDPWCALAEARRLLNDGQLRAAETVARRAREQFTDDVGLRVCDQVIADVSVWVDTTPPPRPTWVHLLRAALRRDPLAAARQARRLDGPGARLTEGLALWVAGNRRQAWTVLRSLAAYGDPDEPAQLAAQLALATISGVGTRPVEDTVANVDDIAAEASRRGWTWIARIATGLTLAVGPPRSRQALAEVLAEHEARSDRVAAAFISMAGAIAQVRGDSARVSDLTAVALRLRELDCGSLAVWCDAIASLKAAAHDLPDAEQMARAAEGQARRAAVPGAACFAYSALVLVDTENSAEELTLARSTAIEIGLAIRPWEWFPAHQSARSRPAERPAAGLAAAERPPAASAAPPSPPEHPPAPSTAAAATTPSSATPGADTPGAATPSSATPGADTPMTDTPPAGIPAAPSPSSPGTGVRVDLRCFGGFELRVHGRSVDLSGVRPRVRALLKFLGIHAGHPVHRELITDALWGELDAEAGMRSFQVSLSQLRAVLEPGVPGRRSRIIQRVGEAYRLNLSPDSRSDVFEFEVALGEAKVARLDRDQDRVRQALTRALDAYQGDLFSEEGAPAWVLTPRERLRAGAAEAAAQLAELEFRAERWTAAVSAAQRSIDIDPYRDDAWRAQVAALRRAGEPAAAQRALRAYRAVLAELGVDSELTGL
>NZ_CP042828|349907:383260|371860_373807_-|WP_147915531.1|plate|DBSCAN-SWA
MLPAPDLDDRRFQDLVDDAKRYIQVSCPEWSDHNVSDPGVTLVETFAHMVDELSYRLNRVPDRLYLTFLDLIGVQLHPPAAATVDLTYWLSAPQTEDVRVPAASQACTPRQEDEDPVVFATLRDLVVPPRELLHTATQPNDGEPTNRSSELRDGDRFSVFTSPPVPGDVLLVGLDDAAPGCIVSVHVDAQVEGKGVDPRFPPLRWEAWCEGGWRSCEVDHDGTGGLNRSGDVLLHVPAEHETSVIGGERAGWLRCRVIEPDPGFPFYSVSPTISAASAVTMGGTVPAGHARTVTEEVLGLSEGIPGQVFTLAHAPVTAGGGVVLEVAAGDGWQEWAEVETFAGSLPESTVFRLDRAIGQLILPPAVREADGTLRHYGAVPAKGAPLRVRSYRTGGGPAGNVAPRAVTVMRDLVPLVDRVVNRRAGLGGRAPETVQQAMVRGPISLRTLDRAVTAEDYEVLARRAAPGIARVRCVVAESAEDAGGVRLLVVPAAVPDAQGRLRLEDLLPSERALQRITDYLGERRPVGARLLVEPPFYQGVTVVARIAARPRANAERLERQALEALNAYFDPITGGPDHAGWPFGRPVQAGEVYAVLQQLTGLELIEDVKLFGADPITGKRGEPTTRIDLDASGLVFSYQHQVRASGGR
>NZ_CP042828|349907:383260|352552_352705_+|WP_168211606.1|DBSCAN-SWA
MRTTLVPACAREPIAAGAQVAEPAAVLFVVLPTLRAVHGPPAPDDAVPGD
>NZ_CP042828|349907:383260|356140_356932_+|WP_147915522.1|DBSCAN-SWA
MRRSAAAVLTGALLALGLSACSPGPVDPTADCSDNGSPPPGEPGSAEVLLTAGNATGTSLLTTVLYADGWVLTLAGEEESGLNALAPPMMAPTPPAARQWQPAYLGSCQLEAVAGLAAEELDEDQRLGSPQITDRASTIVTYYGGDRPTTATAYALGQEEGSDLSRSDEAGREVLKGVIAALDEAPAEGDLLAVETVQVIISGPEADLPTDWPGPSRADMIPAGERCGELTGQDARDVFDYVAGDDIDALRLEVMPPGLPTCT
>NZ_CP042828|349907:383260|369978_371322_-|WP_147915530.1|DBSCAN-SWA
MQTCPDCGVRNEDGELFCGACGTYLEWEEHGVEAASSSSSSTTAELTQAEPAPERVVEPAPQAVEQGAEPPPRPAAAQAAEPAPQAAVQEAGEPATEVRNTPEAPTAVESVPPTRATRATRATRARTAVDHPPTTGTPPPTAAATAETPAGVGPVKPSVKPVKPAAIKPAAAVPGPVQPAAARPRRHVPPAEKDEPSPAPGDLICGACGAGNAPHRNFCRRCGASLADAPTQGRGGWWRRWRDRRRARRDGPKAGTRPKRRRRRRFPTKTVVLLVVLALLGGGGYYFRDELGTGYHAVLDRVAGNDPVNPAEVTASSSASDRGPDLARDGISDRSWAPEATGDGAGEWLQFEFDEPFRLVTVLLTAGASTADETRLLEARPSRVRLTVTTADGAEQIHDVDVVDTGEPQPISLPTSDVVSVRMTILSAYGATDDVHVAVAEVEFRGR
>NZ_CP042828|349907:383260|354697_355081_-|WP_147915520.1|DBSCAN-SWA
MSSYDPPSYNPNAFVAPPPGGGNRSTNVPGRIALIVGVALTLLQLARILVIWSMPMDVGGGSDGLWRAVDLGFTVGEAVLAVLAVITGAVGLAGRPRPRGAAAAGLALGTSTLLFLLLNVTMPLIYQ
>NZ_CP042828|349907:383260|365636_366680_+|WP_147915528.1|DBSCAN-SWA
MAVTRAEVATLAGVSPAVVSYVINGGPRPVAAQTRLRVEAAIDELGYRPNRIAAALRGGMTRSIGLLTPSPGNPFFAELSEALVRELFNRGNTLSVGITDDDISRERLYLRSFVDRRVDGIILTSAQAVTTLRELQAPELPVLVMDRVGQDDTPTFSRVHVDNAHGARLATEHLQGHGHRVIGCIAGPWPVPLSDERVRGWREQQERHGGDHRPALVEHAEFSESGGYAAAWALLGPDSRRGASGVPMPTALFVASDSQALGVILACRDRGLRVPEDIAIVSFDGTASGRYANPPLTSLRQPVVDMALLAVGALLERIHDPTLAPMHEALKGNLVIGQSCGCSTPVG
>NZ_CP042828|349907:383260|381715_383260_-|WP_147915540.1|tail|DBSCAN-SWA
MPTYLSPGVYVEEVEAGSRPIEGVGTAVAAFVGLAEKGPVNTPTLVSNWTQFAETFGEFVPQSYLAHAVYGYFLNGGGNSYIVRIGAENGEGKRGSRKQISGPAKADVSGFAITAKDSGTKKISVAVEATEEEKASEDKFKLVIKVDGKPTETFDGVTTKKGADNVATKVSQESKLITIEQVAQGSAVMKPTKGEVELVAPEPEREPPTPQRLGTDDYVGDAAARTGFAGLEAIEDVTMLAVPDLMAAYEQGAIDLEAVQAVQLAMIAHCELMGDRMAILDPPPNLNAQQIKEWRVDGAGYDSKYAALYWPYVKVFDPASGTNSFVPPSGHMAGVWARNDDTRGVHKAPANEVVRGAISLQTSITRAEQDLLNPVGINCVRSFPGRGIRVWGARTLSSDPAWRYLNVRRLFNYLEESILIGTQWVVFEPNDDALWSRIRRTIAAFLVNEWRKGALFGLTPDEAFYVKCDRETNPAEAIDAGQVTCQIGVAPVKPAEFVIFQLAQFSGGASLVNE
>NZ_CP042828|349907:383260|371321_371861_-|WP_147919266.1|tail|DBSCAN-SWA
MRGVIAGQPSPFPVAHRLPGVLQEDEFLGRFLGAFDEALAPLFLSLDGLGAYVDPQLAPTDFLDWLAQWVGIEVDEAWTVAQRREIVAGAVAVHARRGTTAGIAGAVRLIVDGEVEVTDNGGDAWSAEPGGALPGRARPRVTVRVRPRPGTSVDEARLDAVVTAVKPAHVTHRIRVVND
>NZ_CP042828|349907:383260|377263_378025_-|WP_147915536.1|DBSCAN-SWA
MPTASLPTASLSPAGRTSPDLGLPVGTFESGPELLPSSAALQRHGTTTALLGTARPPAGRLTAAFATSPRGASHLTRPSPPGAPRLPSRGTPSSTPAPRTPTASLARSLSAATTEHPGSALLAPTRPPVQSPSDPAPDTGPPLTVVAQRARGFLGNHRPLPPVPQRPATSLPQRPATPLPQEPPPPDDPPSAPTAASAGPVPPTEPAPSATPAKLSPPELDTLAQQLLDPMMRRIRNELLLDRERRGRRGDWR
>NZ_CP042828|349907:383260|373809_374217_-|WP_147915532.1|DBSCAN-SWA
MTSDFIGSGWTFPVRTSRTGAIALASGDAEIEQSIRLILATAPGERPMRPEFGCGVHHFVFAPADASTAGDIAYAVRVALERWEPRIELASVTVRFDEVDSGLLYIDIAYAVRGTNDPRNLVFPFYVIPDHEEGA
>NZ_CP042828|349907:383260|362799_363768_+|WP_147915526.1|DBSCAN-SWA
MSVQARAAARTPATQRRGAGGGLGRRRSRRRTKELFWAAVFLLPALIAIVSMRIAPTVSAAVSSLHQGFPGGVLAAEFSGLANYSELFGNDMFRDTVIRTIVFNVIINPLQVAIALIISVLLTRKIVAPNLWRMLVFVPATVPIVGSSIVWGIAFRQDGPINAILAALGGNPQPFLTSPSQAMASIMVVISWIGIGYWMLFLVSGLQSIPDEYLEAAKLDRAGTIRTFFSITIPLLKRPLLFVLVADTVANFVLFVPIQMLTNGGPQNSTTMQMFNAYRTTYTYSSKNLGAAEVMILTVIMLAFVALQFRLLREDRPTRRKR
>NZ_CP042828|349907:383260|361466_362783_+|WP_147919264.1|DBSCAN-SWA
MRHLRPAAALIGVAALALTAACSGSESSGGSAEGGDWSIPDEDPTATVQVLGHQDTEIVQPVIDAFHEAHPDITIAYESVPFDQLNSVLDARIGNQDGNPDVYWADQPRIAALSSRGYTEDLTDQFAELTDAFDSAPLESSSFEDRLWSLPIANSTQLLYYNVDLLEQTGAELPSANPEERMTWEELHDRAQEAVDGGAENGFMFGQMHRYYQLEPLPVSMGGSAGGTGEGNLTPDITSDAWVDSMAFYQSLFTDGLHPTGVTPEQSSDEFLTGSTAYMVQGNWLVPSLAEADFEWGVAAHPSFDGGDPVTPTGSWSLAMSPFSDDKEAAAVFMRWMAIDDGGGYALFLEAPELPATPEGKEAYFARDIFSSDAGQDAAAIIDYETANTGVPRLQTVGYVEFEEILGRAFSDIANGADPATALASATDELTTAWAKYQ
>NZ_CP042828|349907:383260|352716_353259_+|WP_147915517.1|DBSCAN-SWA
MGELLGVTPLEALAVVLGTAGMYVTMVIIIKLVGQRMLSSMSSFDVAAVIAFGSILGRAALGEAPRLAAGILSLATLVAMQAVAGLVRSVRRGGRLIVSEPVLLMAGSAVVEENMRHCHVVLAELQSRLRQAGIRHRGEVAAVVFEPSGAISVLRRGDGIEENLLDGVRGGELVPRELLR
>NZ_CP042828|349907:383260|351963_352443_-|WP_147915516.1|DBSCAN-SWA
MPVVSAEVTVPVDAQTAFALSQTTGEVRLRWDRFVRRQHFLDGATHPGKGVRTLTVHRWGARMVSEYVSYAPPRNVGMRMVTGPWFFAKMAGGWRFEEAGPGQARAVWKYNFSCRPNWLAPLAEKIGTWVLGREIQRRIDGFAAGCADPVVLATVADRD
>NZ_CP042828|349907:383260|380628_380787_-|WP_168211607.1|DBSCAN-SWA
MTYAPERLYEEVAYVAYHFHWPQHDILDLEHGQRQRYVHEIATINRRMTQEV
>NZ_CP042828|349907:383260|381232_381682_-|WP_147915539.1|tail|DBSCAN-SWA
MPLPDAMDLAAGYGFSVTIDGVEVPYVMEVAGLKTEVDKIAFQQQAKDGKFITRQMMGRQKPGEFTVKRGLTDSKTVTDWLKEVMGGKLGASRKTAEVTIFASDNSVVKKLSYRNCWVKDVEVSGSLKAGSTDPLVEAFTVCWDEMEFS
>NZ_CP042828|349907:383260|360387_361338_+|WP_147915525.1|DBSCAN-SWA
MRVILDTDMAMGAPGSEIDDGFALALLLADDVFQVELVTSVNGNIDVESGTYLSLELLQRLGRSDIPVVRGAAAPMLEPEKRRGAPEAVRTAFGHHQATPGFAAAEIARRVLDAPGEITIVAIGPLTNVALAIAMEPAVARAVKEIVVMGGVFLGHTQVADMPGEFNWWVDPHAARAVLHSGAPVRLIGLDVTTRVRLTREHARRMAASGRAFGAFAGDCTIAWLDRLSRDRPAEVEGGDSCAMHDPLAVAALSRPELLTWQDAHVDVLTAEPAGRGVAIADLQSRTDAPAPNAQIAVDVQVEAFMDYFLDHIAAY
>NZ_CP042828|349907:383260|379907_380159_+|WP_147915537.1|DBSCAN-SWA
MYPDSAARWAMTSAIGAEYDVTGAGIGSAAGVADAAAGAEEILGPSTGLAPSSGVAATEAPDPVCPGPDEGRSAARSSAPPRA
>NZ_CP042828|349907:383260|354255_354660_-|WP_147915519.1|DBSCAN-SWA
MSTGFGPDPHHTGYAATAYQPGAGRGRNPAGRLALVAGILVVLIGLVQQVLALLLPYLMHRYDLSASAVSLRFNLIGGIVTTVFALVALIAGGIGLSGTGKPKAAAGAGLALGVTAVLSVLMALIAPSIITAVV
>NZ_CP042828|349907:383260|363764_364625_+|WP_147915527.1|DBSCAN-SWA
MSAPASLRRRSRLERRSPLLTIGAVLVAMIFILPAVWLLVGSLRPSAEIFSSISPLSWRILIPSSVSLDNYIALLTGPFGRAMGVSLLVCFLTVALGLVMSATAAYALAVLQFPGRSVVFAFVVISFMVPFDAIAIPLSQLFTGWGLTNTIMGLVLPGIGNGLAIFNLRQYFLSIPTSYREAATIDGASEPRVLASVYTPLGGTALANSALLIFLGQWTAYLWPLLVVSEARLQVAPVALARTFGEHEFNFGENFAGAVLLSLVPALTMFILQRSFGGLALATGEK
>NZ_CP042828|349907:383260|350720_351668_-|WP_147915515.1|DBSCAN-SWA
MDLSRLAAAQFGIVSRAQALAERSAEAVRWKLARGSWQRVHPGVYAVHDQPLGWFARASAALLYYGDDAALSLESAAFILGLASRQPQLVHVDVPANAGRQRRPATRVRRRHRLLTVSRRGLLVTAPAFTVIDLGDTPTASREDAIATAARAVQRHRTTAEELMAELEQRRSHRHRRALELSLGIVAEGAESVLEVDFVIRVVQAHGLPEMRMAVADRAAGRTIRRDFVDAAHRLVVEVDGRAAHEGSRGADIRRDRATAARDVVTLRAEWVDVYYAACQLAAEIFATARGRGYRGELWPCGPGCEAARSLRRSA
>NZ_CP042828|349907:383260|380783_381233_-|WP_147915538.1|DBSCAN-SWA
MRRGSPPELVDAPAATEQPGASAAQAELRTEFDFVLPRGYQDSHGTVHREGTMRLATARDELLPLYDARVQENAAYTTVVLLGRVITSLGTLGSVTSSVVENMFASDVAFLQDLYRRVNTEGHARAAVSCPSCAHRFTLDLSDGRLGES
>NZ_CP042828|349907:383260|376822_377257_-|WP_168211925.1|tail|DBSCAN-SWA
MAEVDTAVTLHFVVSIDNRNLGAFSSCEGLGCEVVLETRQEGGNNQFTWQFPSRISYPTVKLTRPLGRDTSKIGEWITSITQGYSRSTATIKAMTPDATVVADWGLDGVVPVRWSGPSFNPDSPQVATETLEVAHHGFIAAQGA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_147919263.1|349907_350627_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_147915515.1|350720_351668_-	hypothetical protein	NA	NA	NA	NA
WP_147915516.1|351963_352443_-	SRPBCC family protein	NA	NA	NA	NA
WP_168211606.1|352552_352705_+	hypothetical protein	NA	NA	NA	NA
WP_147915517.1|352716_353259_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_147915518.1|353346_354204_+	hypothetical protein	NA	NA	NA	NA
WP_147915519.1|354255_354660_-	hypothetical protein	NA	NA	NA	NA
WP_147915520.1|354697_355081_-	hypothetical protein	NA	NA	NA	NA
WP_147915521.1|355352_356066_+	hypothetical protein	NA	NA	NA	NA
WP_147915522.1|356140_356932_+	hypothetical protein	NA	NA	NA	NA
WP_147915523.1|356998_359419_-	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_168211924.1|359415_360234_-	beta-phosphoglucomutase family hydrolase	NA	NA	NA	NA
WP_147915525.1|360387_361338_+	nucleoside hydrolase	NA	NA	NA	NA
WP_147919264.1|361466_362783_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_147915526.1|362799_363768_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_147915527.1|363764_364625_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_147919265.1|364654_365572_+	ribokinase	NA	NA	NA	NA
WP_147915528.1|365636_366680_+	substrate-binding domain-containing protein	C6ZCU4	Enterobacteria_phage	2.6e-25	29.8
WP_147915529.1|366764_369992_+	hypothetical protein	NA	NA	NA	NA
WP_147915530.1|369978_371322_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_147919266.1|371321_371861_-|tail	phage tail protein	NA	NA	NA	NA
WP_147915531.1|371860_373807_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_147915532.1|373809_374217_-	GPW/gp25 family protein	A0A0M4RE59	Salmonella_phage	4.0e-06	37.3
WP_147915533.1|374227_376045_-	VgrG-related protein	NA	NA	NA	NA
WP_147915534.1|376031_376811_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_168211925.1|376822_377257_-|tail	phage tail protein	NA	NA	NA	NA
WP_147915536.1|377263_378025_-	hypothetical protein	NA	NA	NA	NA
WP_147915537.1|379907_380159_+	hypothetical protein	NA	NA	NA	NA
WP_168211607.1|380628_380787_-	hypothetical protein	NA	NA	NA	NA
WP_147915538.1|380783_381233_-	hypothetical protein	NA	NA	NA	NA
WP_147915539.1|381232_381682_-|tail	phage tail protein	NA	NA	NA	NA
WP_147915540.1|381715_383260_-|tail	phage tail sheath family protein	A0A1C3NFK8	Phage_NCTB	6.1e-31	28.3