CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP043329	Pedobacter sp. CJ43 chromosome, complete genome	7 crisprs	WYL,DEDDh,RT,cas3,csa3,DinG,PD-DExK	0	1	3	0

1. NZ_CP043329

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043329_1

• CRISPR_ID: NZ_CP043329_1
• CRISPR_location: 94446-94681
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP043329_1

Consensus_repeat	Method
CTGCGGTCCTCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTT	PILER-CR

spacers of NZ_CP043329_1

>1.1|94496|43|NZ_CP043329|PILER-CR
CCCTGTTTCCAGTTTTGTATCTATTAGACTATTTCTCTGCGGT
>1.2|94589|43|NZ_CP043329|PILER-CR
CCCTGTTTCCAGTTTTGTATCTATTAGACTATTTCTCTGCGGT

CRISPR arrays and Neighbor proteins around NZ_CP043329_1

CRISPR arrays

The CRISPR arrays of NZ_CP043329_1

>merge|NZ_CP043329|1|94446-94681|PILER-CR
CTGTGGTCATCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTTCCCTGTTTCCAGTTTTGTATCTATTAGACTATTTCTCTGCGGTCTGCGGTCCTCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTTCCCTGTTTCCAGTTTTGTATCTATTAGACTATTTCTCTGCGGTCTGCGGTCCTCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTT

>NZ_CP043329|1|1|94446-94681|PILER-CR
CTGTGGTCATCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTT	CCCTGTTTCCAGTTTTGTATCTATTAGACTATTTCTCTGCGGT
CTGCGGTCCTCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTT	CCCTGTTTCCAGTTTTGTATCTATTAGACTATTTCTCTGCGGT
CTGCGGTCCTCGGTCATCGGACTTCTACCATCTGTTTCCAGTTCGCTGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149073522.1|91990_92848_-|glycosyltransferase	unknown	unknown	gnl|CDD|133005
NZ_CP043329.1|WP_149073524.1|94854_95118_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149073516.1|84840_85671_+|prephenate-dehydratase	unknown	unknown	gnl|CDD|270349
NZ_CP043329.1|WP_149073518.1|86833_88078_+|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|238797
NZ_CP043329.1|WP_149073525.1|95676_97083_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149073517.1|85730_86834_+|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl|CDD|273577
NZ_CP043329.1|WP_168199342.1|95388_95562_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_168199340.1|91431_92001_-|exosortase/archaeosortase-family-protein	unknown	unknown	gnl|CDD|275031
NZ_CP043329.1|WP_039453658.1|82529_83171_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|319790
NZ_CP043329.1|WP_149073515.1|83404_84472_+|3-dehydroquinate-synthase	unknown	unknown	gnl|CDD|341474
NZ_CP043329.1|WP_149073526.1|97113_98076_-|glycosyltransferase	unknown	unknown	gnl|CDD|133039
NZ_CP043329.1|WP_039453661.1|83201_83408_+|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl|CDD|379097
NZ_CP043329.1|WP_149073532.1|104023_105043_-|glycosyltransferase	unknown	unknown	gnl|CDD|340832
NZ_CP043329.1|WP_149073529.1|100276_101584_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340825
NZ_CP043329.1|WP_149073531.1|102792_104034_-|glycosyltransferase	unknown	unknown	gnl|CDD|340831
NZ_CP043329.1|WP_149073527.1|98041_99250_-|glycosyltransferase	unknown	unknown	gnl|CDD|340831
NZ_CP043329.1|WP_149073528.1|99665_100280_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|224748
NZ_CP043329.1|WP_149073519.1|89556_90645_+|chorismate-synthase	unknown	unknown	gnl|CDD|376510
NZ_CP043329.1|WP_149073520.1|90896_91454_-|colanic-acid-biosynthesis-acetyltransferase-WcaF	unknown	unknown	gnl|CDD|236703
NZ_CP043329.1|WP_149073530.1|101588_102809_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340825

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149073522.1|91990_92848_-|glycosyltransferase	gnl|CDD|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	3.64742e-69
NZ_CP043329.1|WP_149073527.1|98041_99250_-|glycosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.11631e-29
NZ_CP043329.1|WP_149073516.1|84840_85671_+|prephenate-dehydratase	gnl|CDD|270349	cd13631, PBP2_Ct-PDT_like, Catalytic domain of prephenate dehydratase from Chlorobium tepidum and similar proteins, subgroup 2; the type 2 periplasmic binding protein fold. Prephenate dehydratase (PDT, EC:4.2.1.51) converts prephenate to phenylpyruvate through dehydration and decarboxylation reactions. PDT plays a key role in the biosynthesis of L-Phe in organisms that utilize the shikimate pathway. PDT is allosterically regulated by L-Phe and other amino acids. The catalytic PDT domain consists of two similar subdomains with a cleft in between, which hosts the highly conserved active site. In gram-postive bacteria and archaea, PDT is a monofunctional enzyme, consisting of a catalytic domain (PDT domain) and a regulatory domain (ACT) (aspartokinase, chorismate mustase domain). In gram-negative bacteria, PDT exists as fusion protein with chorismate mutase (CM), forming a bifunctional enzyme, P-protein (PheA). The CM in the P-protein catalyzes the pericycle isomerization of chorismate to prephenate that serves as a substrate for PDT. The CM and PDT are essentail enzymes for the biosynthesis of aromatic amino acids in microorganisms but are not found in humans. Thus, both CM and PDT can potentially serve as drug targets against microbial pathogens. The PDT domain has the same structural fold as the type 2 periplasmic binding proteins (PBP2), many of which are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.96959e-91
NZ_CP043329.1|WP_149073518.1|86833_88078_+|3-phosphoshikimate-1-carboxyvinyltransferase	gnl|CDD|238797	cd01556, EPSP_synthase, EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.	2.77989e-98
NZ_CP043329.1|WP_149073531.1|102792_104034_-|glycosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	5.35522e-40
NZ_CP043329.1|WP_149073517.1|85730_86834_+|3-deoxy-7-phosphoheptulonate-synthase	gnl|CDD|273577	TIGR01361, DAHP_synth_Bsub, 3-deoxy-7-phosphoheptulonate synthase. This model describes one of at least three types of phospho-2-dehydro-3-deoxyheptonate aldolase (DAHP synthase). This enzyme catalyzes the first of 7 steps in the biosynthesis of chorismate, that last common precursor of all three aromatic amino acids and of PABA, ubiquinone and menaquinone. Some members of this family, including an experimentally characterized member from Bacillus subtilis, are bifunctional, with a chorismate mutase domain N-terminal to this region. The member of this family from Synechocystis PCC 6803, CcmA, was shown to be essential for carboxysome formation. However, no other candidate for this enzyme is present in that species, chorismate biosynthesis does occur, other species having this protein lack carboxysomes but appear to make chorismate, and a requirement of CcmA for carboxysome formation does not prohibit a role in chorismate biosynthesis. [Amino acid biosynthesis, Aromatic amino acid family].	1.57517e-51
NZ_CP043329.1|WP_168199340.1|91431_92001_-|exosortase/archaeosortase-family-protein	gnl|CDD|275031	TIGR04178, hypothetical_protein, exosortase/archaeosortase family protein. This model represents the most conserved region of the multitransmembrane protein family of exosortases and archaeosortases. The region includes nearly invariant motifs at the ends of three predicted transmembrane helices on the extracytoplasmic face: a Cys (often Cys-Xaa-Gly), Asn-Xaa-Xaa-Arg, and His. This model is much broader than the bacterial exosortase model (TIGR02602), and has in intended scope similar to (or broader than) pfam09721.	0.00315599
NZ_CP043329.1|WP_039453658.1|82529_83171_+|HAD-family-phosphatase	gnl|CDD|319790	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive. This family includes the N-terminal phosphatase domain of human soluble epoxide hydrolase (sEH). sEH is a bifunctional enzyme with two distinct enzyme activities, the C-terminal domain has epoxide hydrolysis activity and the N-terminal domain (Ntermphos), which belongs to this family, has lipid phosphatase activity. The latter prefers mono-phosphate esters, and lysophosphatidic acids (LPAs) are the best natural substrates found to date. In addition this family includes Gallus gallus sEH and Xenopus sEH which appears to lack phosphatase activity, and Escherichia coli YihX/HAD4 which selectively hydrolyzes alpha-Glucose-1-P, phosphatase, has significant phosphatase activity against pyridoxal phosphate, and has low beta phosphoglucomutase activity. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.63683e-40
NZ_CP043329.1|WP_149073515.1|83404_84472_+|3-dehydroquinate-synthase	gnl|CDD|341474	cd08195, DHQS, Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis. Dehydroquinate synthase (DHQS) catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) to dehydroquinate (DHQ) in the second step of the shikimate pathway. This pathway, which involves seven sequential enzymatic steps in the conversion of erythrose 4-phosphate and phosphoenolpyruvate into chorismate for subsequent synthesis of aromatic compounds, is found in bacteria, microbial eukaryotes, and plants, but not in mammals. Therefore, enzymes of this pathway are attractive targets for the development of non-toxic antimicrobial compounds, herbicides and anti-parasitic agents. The activity of DHQS requires nicotinamide adenine dinucleotide (NAD) as cofactor. A single active site in DHQS catalyzes five sequential reactions involving alcohol oxidation, phosphate elimination, carbonyl reduction, ring opening, and intramolecular aldol condensation. The binding of substrates and ligands induces domain conformational changes. In some fungi and protozoa, this domain is fused with the other four domains in shikimate pathway and forms a penta-domain AROM protein, which catalyzes steps 2-6 in the shikimate pathway.	5.38463e-152
NZ_CP043329.1|WP_149073526.1|97113_98076_-|glycosyltransferase	gnl|CDD|133039	cd04196, GT_2_like_d, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	7.10562e-26
NZ_CP043329.1|WP_039453661.1|83201_83408_+|RNA-binding-S4-domain-containing-protein	gnl|CDD|379097	pfam13275, S4_2, S4 domain. The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4.	7.69605e-23
NZ_CP043329.1|WP_149073532.1|104023_105043_-|glycosyltransferase	gnl|CDD|340832	cd03802, GT4_AviGT4-like, UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.	1.41267e-93
NZ_CP043329.1|WP_149073529.1|100276_101584_-|glycosyltransferase-family-4-protein	gnl|CDD|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	1.03531e-22
NZ_CP043329.1|WP_149073528.1|99665_100280_-|acyltransferase-family-protein	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	5.75381e-18
NZ_CP043329.1|WP_149073519.1|89556_90645_+|chorismate-synthase	gnl|CDD|376510	pfam01264, Chorismate_synt, Chorismate synthase.	0
NZ_CP043329.1|WP_149073520.1|90896_91454_-|colanic-acid-biosynthesis-acetyltransferase-WcaF	gnl|CDD|236703	PRK10502, PRK10502, putative acyl transferase; Provisional.	1.20997e-79
NZ_CP043329.1|WP_149073530.1|101588_102809_-|glycosyltransferase-family-4-protein	gnl|CDD|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	2.91745e-11

Protein sequences

>NZ_CP043329.1|WP_149073522.1|91990_92848_-|glycosyltransferase
MNTKPVPISIIILTFNEEKNIKACVESALDFAEEIFVVDSGSTDATLEILKNYPVQIVQHPFENYSQQRNWAIQHLPIRTHWILNMDADHRLTEEFRLEVSAIFSKPIADDIHGFLASRKTIFMNKWIKYGGHYPTYHAVLFRKGKGLCEEKLYDQHFKVAGKTQKLKGDIIDLITESLSTFTLRHDKWSNLEAFEQFHPQQQGSVIKGSLQNDNPIARRRYMKNLYERFPLFVRPFVYFFIRYFLRLGFLDGKEGLIFHFLQCFWFRFLIDAKIYELKKQKDGL
>NZ_CP043329.1|WP_168199340.1|91431_92001_-|exosortase/archaeosortase-family-protein
MGYNQKLSKFVFALLLIYFALDYFFEFWIGICAPGGLYWPFAHQHLNFIAWYRDFLISGSQVIAALWGIKSISNATAMLLIGYGGVKIVYSCLGYGIISLLIAFGIAVPDKKFKNRLIFILSSVLLFSLFNMLRLFVVAFYAKTVAGMRVDHHDIFNWICYIIIFTGMYFWMNKKNAPNKKSHVGESTT
>NZ_CP043329.1|WP_149073520.1|90896_91454_-|colanic-acid-biosynthesis-acetyltransferase-WcaF
MSEKVQLKKKFDTGKFDHGASVLKQVLWYFCSALFFRSGLIPFSIILVWMLRLFGAKIGRDVRVKPYVHIKFPWKLSLGDHSWLAECFIENLDHVHIGANCCVSQGAMLMTGNHDYKSKNFDLLTKPIILEDGVWIGARAIVCPGVTCKSHAVLSMAAVAHHDLEAYSIYQGAPAVKVKERVVGG
>NZ_CP043329.1|WP_149073519.1|89556_90645_+|chorismate-synthase
MAGNSFGKVFRITTFGESHGAAIGVIIDGCPPNIALDLDFIQYELDKRKPGQSKITTQRKESDTCQILSGVFEGKTTGTPIAIVIPNEDQKSKDYDHNKDTFRPSHADYTYQHKYGIRDHRGGGRSSARETAARVAAGAIAKLALKKVGIEVVAHVSSVGTIDAPHIDFTSVEDFEALRESNIVRCADPSTAKEMINLIDQIRKEGDTIGGKVSCIVKNCPVGLGEPVFDKLHADLGKAMLSINAVHGFDYGSGFDGSTMRGSEHNDIFEKNHLGDVITRTNFSGGIQGGISNGMDINFRVAFKPVATIMTNQQTVNKDGDAAEIKGKGRHDPCVVPRAVAIVEAMAALVIIDHYLRNNLYQ
>NZ_CP043329.1|WP_149073518.1|86833_88078_+|3-phosphoshikimate-1-carboxyvinyltransferase
MSGNILISNAPKQIQETIRLTGSKSESNRALIIQALSGGKVKVENLSAAADTVTLNHILNSLAQEPAEVNVGPAGTAMRFLASYLTVKGVQTVLTGTERMKQRPIGILVDALNKIGGQITYVEKEGFPPLQIAPAFKQTQNKVSIKGDISSQYITSLLLVAAALEEGLTLDIEGELTSKPYVEMTLGFLVQCGIQHTWEDNQITIAHQEFESSTLVVEPDWSAASYWYAFAALADEATITLPYLRQNSLQGDSVIAAIMAHFGIATAYSEEGIIIKKVPHQLSEKFFDLKDCPDLAQTVIVCSAALGHEATFTGLETLKIKETDRVAALQNELAKIGVKLIEENLNYTLDCSGLHFPDKISIATYEDHRMAMAFAPLASFVKEVEVEEANVVEKSYPSYWEDVKKIGFRLDDLK
>NZ_CP043329.1|WP_149073517.1|85730_86834_+|3-deoxy-7-phosphoheptulonate-synthase
MKLNLNIQPLSSWMKVSSEPLIISGPCSAETEEQLLATAHLVKNTGKVSVLRAGIWKPRTRPGEFEGIGSIGLQWLKRAKEETGLPTAVEVATAKHVEEALAAGVDILWIGARSTVNPFTVQEIADALQGADVPVMVKNPINPDLALWIGALERINRAGITKLAAIHRGFSSFEKSAYRNEPMWDLAIHLKTLAPELPILNDPSHICGTRDLIPYISQQALDLDMQGLMIESHIDPSVAWTDAKQQVTPAALTEIVNNLTIRKADSSNPEFTDKLQGLRDSIDRIDDQILQKLGERMALVEKIGEYKRDNDVTILQVNRWEEILEKRTALASALKLEKDFTEKVLELIHGESIRKQTEIMNAKTELN
>NZ_CP043329.1|WP_149073516.1|84840_85671_+|prephenate-dehydratase
MSAKKRVAIQGIKASFHEEAAFKFFGEDIDTIECNSFKETFQKLKAGEADYVVMAIENSIAGSLLPNYTLLREYNFPVIGEVYLHIQLHLMALPGVKFEDIKTVTSHPIAIRQCNDFLDDFPHLKVVESSDTAACAKKIKEEQLTDTVAIANNLAAKLYGLEILERRIESNKKNYTRFLILTDKQVDIKDSNKASLCFQVNNNVGSLAAVLNIFAENKINMSKIQSMPVLGKRNEYNFYVDVEWKDTKQYDRAIRDSLKHTSNFSILGEYKKNDKV
>NZ_CP043329.1|WP_149073515.1|83404_84472_+|3-dehydroquinate-synthase
MNPIQSSTYQVYFDNSLQVLQDLLQQGNYSKVFIITDENTGQFCLPVLQEKLPALDNFDIIEIPYGEENKNIDYCIGIWRMLLDFEADRNALVINLGGGVVTDMGSFAASTYKRGIDFIQIPTTLLSQVDASVGGKTGIDIENVKNIIGTFALPQAVIICADFLQTLPERQIISGFAEVIKHGIIADAAYYQDIISLPHAKDISTAQIHASVAIKNKVVLEDPFEKGLRKILNFGHTIGHAVESWSLEHDSSPLLHGEAIAVGMICESYLAHMTGILEEEDFKTIVQDVLKFFPKYKLKEGIENDLLAIMQHDKKNSVGNINFSLPNKIGNCLYNQVVSKDLIIESLAYYRSLNS
>NZ_CP043329.1|WP_039453661.1|83201_83408_+|RNA-binding-S4-domain-containing-protein
MIEFKLEGEFIPLIQLLKATDLVSSGGEAQAVVIDGLVQYNGVTDYRKRLKVRKGDTVKFNNKTIKIV
>NZ_CP043329.1|WP_039453658.1|82529_83171_+|HAD-family-phosphatase
MKAVKTIIFDYGNVIFNIDFKRTQQAFIDLGIQNIEEFFAHKGHDPLFDEFEKGNISAAEWREGIRRKAKQPQLTDQQIDDAWNTLLLGVPDGNHDLLLKIKAQYPTFLLSNNNEIHYDWIMKYLKADFGLADNSSFFIKDYYSHLLRMRKPNADIFEYVLDTHGLKPEETLFIDDSPQHLKTAQELGLQTYLMTAPDNLQLYFSKNGLLRDL
>NZ_CP043329.1|WP_149073524.1|94854_95118_-|hypothetical-protein
MEWYIKKGVVLNLNHFLERAIMSGDWNKKTINKEEFISLIRERIAIVSMERVKADIKRFISNPNVLNIWSTPYFNDLIAHLQVSAEP
>NZ_CP043329.1|WP_168199342.1|95388_95562_-|hypothetical-protein
MTRSPGTEYGGPQSISAIDVKLETGNRELKTDGRSPMTEYGGPQPISARDVKLETGN
>NZ_CP043329.1|WP_149073525.1|95676_97083_-|hypothetical-protein
MGKFKSISPIGHIILVAGLIYSLLSVNPLHTFLAVVLPFILVKLSWKNDEAPILFTALMTQYMAISVKVFYANYSNLAFDDISLHRYPDYINEAYYWGMGGLVTLALGIHFAIRGFKHTNNTSILAASHQFNGDKLGKLYLLLAIAYPILFKLSFSIGGLQQPLSKLIEFKWALFFIFMIYAFYKNEKKMFLWIASAELLFSFTGFFSGFKDYFLILFIGMVVLYGQNFKLQNIIPLGVILIVGFYTLMIWQYVKPAYREFLNAGQKTQTSVRSTEESLFKLYNLVTEIDSTGIKEGFEATVNRLSYIEFLSGAIEHVPYQLEHTNGELWLGAVERVLKPRILFPEKAAIDDSEKARLYTGQDYSGVESGTSISLGYFAESYVDFGKTGMLLILLVFGFVIGSIYRYILKQSPDLLIGTALTIPLFFVIFNYERALDKIFGALFMYLIIYLAFNRLVIKKTIEYLKND
>NZ_CP043329.1|WP_149073526.1|97113_98076_-|glycosyltransferase
MKKISVILPVYNGEKFLIDAMESVLKQNLIDFDFLICDDCSTDKSWDLINKYANHPNIKIFKNKINLGLFKTLNFLLSKTSTDLIHLWSQDDVMKPHCLQECIIFHEKHPDLLMSYSGRDYIDENGKLIELYQKDETPEVISSELYAYISAYWGCIAGNIANVTLTKKGIAKAGNFNENYEVSGDFEMWTRLSKNGDIGFLNQPLIFLRRHLGQLSRSYKSTYLSMKEDIPILLNINEMVADEHRKKVQICLTWKTQVIYFNEMLFLVFKKEINLATKCLFLLANHSNIFLLFFRWLLIRFLRTLKKDMWFYKNILHILK
>NZ_CP043329.1|WP_149073527.1|98041_99250_-|glycosyltransferase
MIDKKLAIVTTHPIQYYAPLFQLLAKETNLMVFYTWGEGSLKKFDPGFGKVIEWDIPLLEDYPYQFLKNESKYPGSHHFKGIINPNLIEHIEEFNPDAIMLIGYAYQSHLQVLRHFKGKTPLWFRGDSTLLDKDTGWKKYIKSIYLKWVYSHVDLAFYVGTANKAYFKKYGLKERQLVFAPHAIDSGRFLVPRKNEAKALRARLGLSKLDILILFAGKFEPKKNPLLLLDAFIALNLPNAHLLFVGNGVLEESLKWRVETLKLKVKNEERKDNRVHFMNFQNQSQMPVVYQASDIFCLPSQGPGETWGLAINEAMISRNAIIASNKVGCAIDLVKNGENGYVFESSDLEGLKVCLSKITLSPSIHQMKDKSQDIIKEWSISNQLKAFINQLNEKNQCDSSSL
>NZ_CP043329.1|WP_149073528.1|99665_100280_-|acyltransferase-family-protein
MNNPTVLKPIGRITSVDMLRGIAALMVCIFHFTNGNKNYLASGHWFRNFGSYGWAGVEIFFIISGFIIPYSLNQSKYTYQNWKDFLIKRISRIEPPYFITILLILALNYVSTLSPYFKGKDLPIDYFNLALHIGYLNSFFDHPWLNPVFWTLAIEFQFYLLMALIFPLLIHSSTYVRATIVFAYLLSMFFFSSKFIFYYSAYFL
>NZ_CP043329.1|WP_149073529.1|100276_101584_-|glycosyltransferase-family-4-protein
MKKILIISPYFPPCNAADMQRIRMSLPYFKEFGWEANVVCVHPDFCEVNKDHLLLEAIPTDIKIYTVKPISKKWTKKIGLGSIAIRSLNAIRKKVDVLLNKEHFDLIYFSTTQFPVCILGNYWKKRFGIPYIIDMQDPWHSDYYINKPKAEQPPKYWFSYRLNKWLEPLAMKHVDGLISVSEAYIKTLQIRYHNILNIPYKVITFGAFDQDFSIAEKHQFDYSSMIPHKNEDVVNVVYVGRGGLDMKDALVKLFSAFRLGLRQEASLFKNIHFYFLGTSYAPDGQGKQTIFPLAQEMGIAAYVTEQTNRIPFYQTLNTLKSADLLFIAGSNDPQYTASKTYPYMFSKNPLLAIFHQDSSAAKIIRECNAGEVITFDMPEDTAIHQIYINLKNTLLKQGKPFIGNESELNNYSARNKTAEQCDFFELVLSSLNTSR
>NZ_CP043329.1|WP_149073530.1|101588_102809_-|glycosyltransferase-family-4-protein
MHQNIKRICLITPGHIASNPRLVKEATALDKAGYKVHIIFTQYMNYLINDDFDILKSNPNISFDYLDWTGSCIKSKVIKLLFGLIHKASLILNLNWLSNLILNRNYFWQLKSAKAYKADLYIAHNVGALSVAANAAEKTLSKYAFDAEDFHREENLSSKVLKSLIHVEDLYLPKAIYITASSPLIAQEYQRIYLRQVIPIMNVFPKIEHVVKKRIENQDKSIKLFWFSQKIGVDRGLIEVIEALGIIKNDLFELHLLGLYNKFTKETILSHVTKASLNHNKIYFYKPIPPDLIFDFAQQFDIGMATEIADVYNREICLTNKIFTYIQSGLAVIASNTVAQLNLFNDYPIDGILYQKRNSNSIAIALSTFLDENKLENSKQNNYILGQTTLNWDIEKQKFLFIINNL
>NZ_CP043329.1|WP_149073531.1|102792_104034_-|glycosyltransferase
MKCSVANPNIAPYIKQTVIAYQESNNLEKFYTTFFEHREYFLTKFLINYLPNLKKNIKRRNLNEIDFNLVKGKPFKELIRVFSARFLDTITTDKIWEWGELSFDQWVANQLDKSLSSIHTYEHAALKTLERAKELGILSFYEQPSQHHALFEKIVKEQLVLYPELKTKNIDLLTNDKAIKRNKRRDNELKVCDYIICNSTFTKKSLLAADIELKKIITIPYGFPKIETLISEKHPTEKISFMNAGSQNLRKGIHILFQAWKECNFGDKAELIMIGKNHLPTSFLKDLPENIKFIPNIPHEELMSFYAKSDVFVLPTLADGFGMVITEAMSRGMPVITTTHSGGPDIIEHKKNGIIIPPNDKEALIASLRWCVENKNKLKELGRNALIKADSYPWKNFRREVIKQIEEKIASKY
>NZ_CP043329.1|WP_149073532.1|104023_105043_-|glycosyltransferase
MRIAISADPFIPVPPINYGGIERIVELLINEYTNLGHTVVLFAHKESKVKCKLMPYPCEGLDKISTLRNTLFISRNIIFGQYDILHSFSRLAYLTFLLPLSIPKIMSYQREPTLSQVKLAQKLAQKNTLLFTGCSNYISKKIAPIAKTSTIYNGVLLDKYTFKPKIGVDAPLIFLGRIEPIKGTHIAIKVAIACRKKLVIAGNIPDNYQNYYRNEIKPFLNEDITYIGPVNDVEKNELLGNALAFLMPIEWNEPFGIVMAEAMACGTPVVAFKRGSVPEVVIDGENGFACDNLEDMICTIKKVANLDRRKVRNSVEKRFSSEVISRQYLSIYKKFNNEM

Crispr_ID: NZ_CP043329_2

• CRISPR_ID: NZ_CP043329_2
• CRISPR_location: 262842-262927
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP043329_2

Consensus_repeat	Method
TCAGGGTTATGAATCCTGCGCTCT	CRISPRCasFinder

spacers of NZ_CP043329_2

>2.1|262866|38|NZ_CP043329|CRISPRCasFinder
AACCATCTGAGCTACCCCGCCAAGGGTTATACATTTTT

CRISPR arrays and Neighbor proteins around NZ_CP043329_2

CRISPR arrays

The CRISPR arrays of NZ_CP043329_2

>merge|NZ_CP043329|2|262842-262927|CRISPRCasFinder
TCAGGGTTATGAATCCTGCGCTCTAACCATCTGAGCTACCCCGCCAAGGGTTATACATTTTTATCAGGTTATGAATCCTGCGCTCT

>NZ_CP043329|2|1|262842-262927|CRISPRCasFinder
TCAGGGTTATGAATCCTGCGCTCT	AACCATCTGAGCTACCCCGCCAAGGGTTATACATTTTT
ATCAGGTTATGAATCCTGCGCTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149073631.1|266292_270711_-|translocation/assembly-module-TamB	unknown	unknown	gnl|CDD|367909
NZ_CP043329.1|WP_149073632.1|270793_271813_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl|CDD|236585
NZ_CP043329.1|WP_149073629.1|259565_261101_-|IS1182-family-transposase	unknown	unknown	gnl|CDD|372705
NZ_CP043329.1|WP_039449710.1|263078_263462_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149073634.1|273815_274391_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|235457
NZ_CP043329.1|WP_052176804.1|274452_274671_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149073636.1|275741_277766_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NZ_CP043329.1|WP_149073635.1|274730_275726_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381375
NZ_CP043329.1|WP_149073623.1|239618_241334_+|family-43-glycosylhydrolase	unknown	unknown	gnl|CDD|350129
NZ_CP043329.1|WP_149073627.1|256261_257233_+|DUF1735-domain-containing-protein	unknown	unknown	gnl|CDD|376046
NZ_CP043329.1|WP_149073626.1|254459_256220_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP043329.1|WP_149073624.1|241547_245660_+|response-regulator	unknown	unknown	gnl|CDD|223715
NZ_CP043329.1|WP_149073630.1|261515_262427_+|IS982-family-transposase	unknown	unknown	gnl|CDD|372648
NZ_CP043329.1|WP_149073625.1|249458_251345_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP043329.1|WP_149073622.1|238256_239354_+|endo-1,4-beta-xylanase	unknown	unknown	gnl|CDD|366032
NZ_CP043329.1|WP_149073633.1|271809_273813_+|hypothetical-protein	unknown	unknown	gnl|CDD|224720
NZ_CP043329.1|WP_039449707.1|263481_264924_+|YjgP/YjgQ-family-permease	unknown	unknown	gnl|CDD|367632
NZ_CP043329.1|WP_149073628.1|257263_259408_+|1,4-beta-xylanase	unknown	unknown	gnl|CDD|214750
NZ_CP043329.1|WP_039449703.1|265058_266264_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	unknown	unknown	gnl|CDD|181774
NZ_CP043329.1|WP_149075818.1|251382_254436_+|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl|CDD|274948

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149073631.1|266292_270711_-|translocation/assembly-module-TamB	gnl|CDD|367909	pfam04357, TamB, TamB, inner membrane protein subunit of TAM complex. TamB is an integral inner membrane protein that forms a complex - the translocation and assembly module or TAM - with the outer membrane protein, TamA. TAM is responsible for the efficient secretion of the adhesin protein Ag43 in E.coli K-12.	2.93951e-28
NZ_CP043329.1|WP_149073632.1|270793_271813_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
NZ_CP043329.1|WP_149073629.1|259565_261101_-|IS1182-family-transposase	gnl|CDD|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	8.30563e-37
NZ_CP043329.1|WP_149073633.1|271809_273813_+|hypothetical-protein	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	2.10461e-08
NZ_CP043329.1|WP_149073634.1|273815_274391_+|aminoacyl-tRNA-hydrolase	gnl|CDD|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	2.74364e-85
NZ_CP043329.1|WP_149073636.1|275741_277766_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.54395e-33
NZ_CP043329.1|WP_149073635.1|274730_275726_-|aldo/keto-reductase	gnl|CDD|381375	cd19149, AKR_AKR11B2, Escherichia coli NADH-specific methylglyoxal reductase (YdjG) and similar proteins. Escherichia coli YdjG is a founding member of aldo-keto reductase family 11 member B2 (AKR11B2). It catalyzes the NADH-dependent reduction of methylglyoxal (2-oxopropanal) in vitro. It may play some role in intestinal colonization.	1.77405e-157
NZ_CP043329.1|WP_149073623.1|239618_241334_+|family-43-glycosylhydrolase	gnl|CDD|350129	cd18617, GH43_XynB-like, Glycosyl hydrolase family 43, such as Bacteroides ovatus alpha-L-arabinofuranosidase (BoGH43, XynB). This glycosyl hydrolase family 43 (GH43) subgroup includes enzymes that have been characterized to have alpha-L-arabinofuranosidase (EC 3.2.1.55) and beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activities. Beta-1,4-xylosidases are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Also included in this subfamily are Bacteroides ovatus alpha-L-arabinofuranosidases, BoGH43A and BoGH43B, both having a two-domain architecture, consisting of an N-terminal 5-bladed beta-propeller domain harboring the catalytic active site, and a C-terminal beta-sandwich domain. However, despite significant functional overlap between these two enzymes, BoGH43A and BoGH43B share just 41% sequence identity. The latter appears to be significantly less active on the same substrates, suggesting that these paralogs may play subtly different roles during the degradation of xyloglucans from different sources, or may function most optimally at different stages in the catabolism of xyloglucan oligosaccharides (XyGOs), for example before or after hydrolysis of certain side-chain moieties. It also includes Phanerochaete chrysosporium BKM-F-1767 Xyl, a bifunctional xylosidase/arabinofuranosidase. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	4.66613e-148
NZ_CP043329.1|WP_149073627.1|256261_257233_+|DUF1735-domain-containing-protein	gnl|CDD|376046	pfam18620, DUF5627, Family of unknown function (DUF5627). This is a domain of unknown function found in bacteria.	2.70481e-62
NZ_CP043329.1|WP_149073626.1|254459_256220_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.53439e-41
NZ_CP043329.1|WP_149073624.1|241547_245660_+|response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.53604e-55
NZ_CP043329.1|WP_149073630.1|261515_262427_+|IS982-family-transposase	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.44535e-84
NZ_CP043329.1|WP_149073625.1|249458_251345_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.42714e-41
NZ_CP043329.1|WP_149073622.1|238256_239354_+|endo-1,4-beta-xylanase	gnl|CDD|366032	pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.	5.06059e-135
NZ_CP043329.1|WP_039449707.1|263481_264924_+|YjgP/YjgQ-family-permease	gnl|CDD|367632	pfam03739, YjgP_YjgQ, Predicted permease YjgP/YjgQ family. Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long and contain about 6 transmembrane regions. They are predicted to be permeases although there is no verification of this.	1.67831e-46
NZ_CP043329.1|WP_149073628.1|257263_259408_+|1,4-beta-xylanase	gnl|CDD|214750	smart00633, Glyco_10, Glycosyl hydrolase family 10.	8.44154e-38
NZ_CP043329.1|WP_039449703.1|265058_266264_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	gnl|CDD|181774	PRK09311, PRK09311, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
NZ_CP043329.1|WP_149075818.1|251382_254436_+|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	1.31217e-135

Protein sequences

>NZ_CP043329.1|WP_149073630.1|261515_262427_+|IS982-family-transposase
MLTSDKIIEIFVKVDDFCKEFEAEIVKHQLDAGHYKVRNRKASLADSEIMTILITFHSGYYTNLKHFYLGFICQHYKDHFPGLVSYNRFVELQQRVAVPMMLFLKTHCLGRSAGINFIDSTHIKVCHNRRIHNHKVFAAVAERGQCSIGWFYGFKLHLIINDKGEILSFYLTKGNVDDRNIKLMTSMTQDIFGKLFGDKGYISKALADLLWGNGIQMITKPRKNMKEFNISQADKIMLRKRAIIECVNDELKNICKLQHTRHRSINNFLMNTMGVLCAYHFFPKKPSLNIIFEDHDKQLLLAA
>NZ_CP043329.1|WP_149073629.1|259565_261101_-|IS1182-family-transposase
MPNKAPVFKPYNQHQIMMLPPSLEELIPESHTVRVVNEVINRINVEPLLSAYQTKGTSSYHPLMLLKVLVYGYVSNIYSSRKLEAACKENIHFMWLSAMNRPDHHTINRFRGERLKDALRKVFEQVVTLLAQEGLLSIEEVYTDGTKIEANANKYTFVWKKAIQTNKEKMKAQINQIWQYAQNISDTEDDLPEPPDLTTINKEKVEEAIAQLNEALADKKNIDKKVKAKLNYINKNFLKNMDKYEQQEAILGERNSYSKTDEDATFMRMKEDHMKNGQLKPGYNTQISTSNQYIVNYTIHPNPTDTTTLALHLAQHQQSFGTAPQSLTADAGYGSEENYALLEELNVAAFVKYGKFDKEQSQRYQDKQLFASDKLYYDEVNDQYICPMGQAMTYVGDSRKQTTTGFKQTYRRYQAKNCSHCPLNGVCHKSKENRIIEINASLNRLKEQAYQLLNSEQGVMHRKKRCYDVEPVFGNIKHNHGFKRFMLRGKKKVEIEWGLIAIAHNLRKKAA
>NZ_CP043329.1|WP_149073628.1|257263_259408_+|1,4-beta-xylanase
MKQYYKIAILGFLATVALGSCAKYETLDYKVDKPLSIANQEEIDSYKSLKSYIDSVKYPNFKFGAAINLSEYVSKGVMYRLINSNFNDITAGYEMKHSSIVRNDGTLNLTNLENLYKVASAAKVSVFGHTLAWHSGQNATYLNRLIAPRIIPGASVPTWDLVTGANFETDAATNYSLNANAVPSFTAAGAGAGGTGRALQVTNASVRTNDYDAQFFIRFSPAVQVGEKYELKMDVRSDVNASYSTQAHVTPGAYKHWDFFGTISSTPTWTNYTRQITVTADMATSGAIAFNLGKTATSFYFDNITLKKYNEKGSGNAGYAYFATNPAAINFWEAQFVHDIPTLQNGQEYTLKFAAKGSIAGNIRAELQSTSNYSSNAFGTIALTAGWKEYTMKVTTTAATRNRLVFSHGDYAGTVTIDNVKLMLGDGPANLIPTSDFETGTGAWGGWGPNTSRGRTADGGGFGGALDQIIEKTSAEKKLIITNAMKDFISKYVEFSKDYVKAWDVVNEPMDDGRPYELKTGIGRSSIAADEFFWQDYMGKDYAVEAFKLARLYGNPTDIHFINDYNLEYSMDKCKGLIEYVKYIESKGAKVDGIGTQMHISTTSDKAKIEEMFRLLAATGKLIKVSELDMGINNKKTTAITEEDLKVQQEMYKFVVEKYFEIIPAAQRYGITIWSPLDSPVNSFWRAGEPIGLWTEGMIRKPSYMGVAEGLKNK
>NZ_CP043329.1|WP_149073627.1|256261_257233_+|DUF1735-domain-containing-protein
MKKILNISIFLLAVLTSCKNGEWAFPDYKVQSVYFAYQTPIRTITLGEDIFDTTLDNEFKCQIMATTGGVYNNDDNINIDITVDNSLAQGLSFGSPIGGLIRAMPANYYSLSASNIVIPRGSLIGGVTVQLTDAFFADPLSARTTYVIPVRMTGVQKADSILSSKNYTLYAIKYINPWTGVYLRRGKDVMVGKNGNTALTQTIVRRQQFVEKDQINSINTRGLKQAEFPVTYRGVGGANVTLNLLLTFDDNGNFTVSPGATGFTATGSGKFVKRGEKKSWGDKDRDALYLNYSIDATDFSVSTTDTLVLRDRGVAFQTFTTVN
>NZ_CP043329.1|WP_149073626.1|254459_256220_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MNRIILFIGFLLTFSSCEKFTEPEPQNNGSFENIYTEPILAQGFLMNGYTRLPSNFWNFTDVATDDAVSNDVGNGFRRIATGQWASNFNPLDQWQNTRAGIQYLNLFLAEVDKVTFDTKDPILNRMFADRMKGEAYGVRAYFMFSLLQAHAGWVDGQLYGFPILTTPETPSSNFNIPRSTFEECMKQIYADLDKAEELLPLDYEDISSPSAIPTKYAGTNTETYNRVFGKLFKLLMTGRIAKAIRAKAALVAASPAFAAGNTTTWADAATYTAEVLNRNGGLSGIAPNGVTWYDNRAEIDALGSGANPREILWRNNISSNSDLELAHYPPSLNGQGRLNPTQNLVDAFPAINGYPISSPLSGFNAASQYANRDPRLARFILFNGGTAGPSSSVINTAADGTTLDALNRDATSTRTGYYMKKLLRQDVSRNPLSINNQKHYKPHIRYTEMYLAYAEAANEAYGPLGMSPNATYSAYDVIKAIRQRAGVGLSNNDAYLESIKGDKELMRALIRNERRLELCFEGFRFWDLRRWNAPLTETAKGVSITNNIHTIIDVEIRNYQDFMRFGPIPFDETLKFSTLKQNAGWQ
>NZ_CP043329.1|WP_149075818.1|251382_254436_+|SusC/RagA-family-TonB-linked-outer-membrane-protein
MRYSRIALFVCVLLTLITGIAIAQDSANITIKAVIKDNNGLPIIGANIIDKVNKIRTASDKTGSFIIETKPESILTINAFGYGIKTVTASKGVNEIILIPESKLTPIAFNTVAPEDVPPGVSNVDFAKMFENNYGTFGFENLEAFAEGFNGNGIWGMSQSLVLIDGVPRDITDIMPTEIDQVTFLKSAAAVALYGSRGANGVILVTTKTGSENGQSISIRSNAGLHVPKSYPGYLGSSEYRALYNEARVNDGLTRLYTDEDIYNHSGIDPIRYPSVDFYSSEYLKSSYARYDVTAEISGGNEKARYYTNMGFNSTGSLLDFGEAAKNNTADRFNIRGNVNMKLNNILKARINASAVFYTSKGVNTDYWGGAASIRPDRFTPLIPISRIDPTDETSLNLVNSSQNIIDGKFILGGRTLDQTNPIAAVYAGGTNNFNARQFQFTTGIGADLKGITKGLTFDSNLGIDYSSSYNQGYRNGYSTFEPTWTSFSGTSTIASLNRLGLDTKTGNEVIADSYYRQTLSLSGQLNYNRTFSEKHNVTGILMGGGFTQSVSQVYQKVTNANTGLSLGYNYNRKYFIELTGSRVNSPRLFGKNQNELSTAGSLGWEISEESFLKDVSFLDNLRITASAGILYTDLNINDYFLYEAIYTQSDGTWHSWNDGVLVRTTDSRRGENLDLKMARREEITLGLQGSIFNNTLSFSGNFFRSTMTGIPIQANVLFPNYFTTGFPNSSFIPFVNYNNDLRTGFDLSLRFNKRIGQVNWSAGSFTTFQSSKATKRAEIVANNNLLRQGRPLDGIWGLRSNGFYNTSEEAAAANAGNGAPKPAFGDVKPGDIKYIDLNNDGLINNQDEVYLGRGGFSGAPLTTGLNLSANWKNFTVFVLATARFGANGMKGFGNAAQSNYFWVNGEEKYSVEVRNRWTPETASTATFPRLTTLNGDNNNRASDFWMYSTDRFDLSKVQITYRLTNNVMKSKVFNGLDFYLTGFNLLTVSQERELLELNLGGTPQTRLYNLGVKASF
>NZ_CP043329.1|WP_149073625.1|249458_251345_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKIFKKTATILALGVIMLVVVSCKEYLDREPESIVSEEIAFKDFTNFQGYTEELYNCIPDFTNRYWTNSWNWGEDEIQTTANTFHFVVKVDNGDFWGWQREFDGWGAGFMDNNGANTNDDRFTKGLYPLAWYGIRKVNVGLANIDLLKNATDEERNLIKGQLLFFRGWFHFMLIQYFGGLPYIDTVIPADQVFNAPRLKYQEAADKVAKDLREAADLLPINWDNTTVGRRTLGKNELRINKIMALGYLGKNYLWAASPLMNFESKGVKAYDVEYSKKAAAAFAELLNLTESGQAPHKLIPFERYYTNFYTFGQQWLIPGGTEAIFRGPYWGAHSSTYGTAKQYTPSIIEGDNIVFSPTANYVAYYGMANGLPIPNTSQADPVSGYDPQYPWRNRDPRFYNDIVFDGQKIVQGTMPANLESNRYTNLFTGGSFRDERSGSRTGYLLYKFTPRTSNRFDQGYAYGQNLNIKLPYMRLADIYLMYAEAITAGYNSANAKDPSFSKSAVDAINVIRDRAGVGHVAAQFIGDPVEFMKEVRRERAVELSFEGHRFNDLRRWLLLIEQPYTLKTAAEFDRAAPLNTALDPKLNRVVNYRERVILQRQFTQKHYWLPLKRADVNIYPQFSQNPGW
>NZ_CP043329.1|WP_149073624.1|241547_245660_+|response-regulator
MKIKLLKCFFIASWILLFVTKSNGQQLDLNFLNISSKDGLSSNLVNTILKDKYGFMWFGTDDGLNKFDGEHFTVYRHKADDNESISSNEILYLYEDEKANLWICTGSGLVLYDRNTDTFKNITSTKDFTVTSVCSYNNNIWVAHYSGLIIFNKEKNTLTQLSLKNKGDINLLAKGVLHIFKDSKNRIWIGTNTGLYSYNSKKQELEKFFHNSNPESIASDYINQIAEDLFGNIWFATDGGLSMWVRNTKKFINYKNNPKNINSLSNNIVYTLASASDGKLWVGTEDGLNIVNPITKKVERVAKNSRNKYGLVGKSVKEIFLDNQGIFWIATFRGGINKYDKNLAFFNLRQSNYFDVYGLSAPVVTSFAKHTKNSIFIGTDGGGLNLYQADNGSFKHITVADNPSEDKNLSILAMENDGDNLWIGTYLNGIYILNTKTGKLKQIKEGNNSQSLSNNNIFCLKRDSKGNIWIGTNGQGVDCYNLQKNEFVNYSSKKVGKYKLPVNGFIRALAEDKEGNIWIGTNGSGIAVYNPITGKSKLISKTNTKLPNDNIYSIYVAVDGKVWIASAGGGLTHYDIETGNMTSFSEEQGLANGVVYKIIEDSYGKIWLSTNKGISSFDTFTKKFKNYSYNNGVQRSPFVIGAGLKLDDGRIFFGGTDGFNYFNPKLISSNKNQQKVILTDLKINNLSVRPGEDSPIQNHISVANEINLDFKQNFLLSFVALNYSSPQENRYSYKLEKFDKEWNYIGQSQTAIYTNLDPGTYIFKVKASSDAGDWTTPITEIKIVVNPPFWRTIYAFILYLFIVVSVLFYIRHRGIQKLKSKFALEQERIQIQSLIEQERLESERIHEFDEMKIKFLTNISHEFRTPISLIIGPIAQLIQQETNSPKYQQLNMVMRNARRLLNLVNQLLDFRNISSNENKLNTTEGDFISFCKEVAESFKDLAEQKGINFDFQSEISSYYTTFDHNKIERIFFNLLSNAFKFTLEGGEIIFKIENAKRKEGLKITIIDTGIGIDENAKEKIFERFFQNESNPAILNQGSGIGLSIAKEFVKMHGGAIEVESIKGEGSTFIIYFPFEKIKNIESAKYKLDTNQDIKLTNEETELEIIVEKALKNEVKPSVLIVDDNEDFRHYLKENLKEQYTIIEAENGKDGWQKVLSSHPQLVVSDINMPQVTGIEFCRKIKLDKRTKHIPVILLTAITGEESQMLGLETGANDYLNKPFNFEILQFKIRNLLTMKEHLKNTYSKQMNVTVKEIEVESENEKLMNKVLHFIESNLTNPKLSVEELSSYIGMSRGSLYTKILEMTGETPVEFIRSIKLKKAANLLEKSDLNVAQICYAVGFSTPNYFARAFKTKYNMLPSEFINLKRNKGNS
>NZ_CP043329.1|WP_149073623.1|239618_241334_+|family-43-glycosylhydrolase
MKQKKWMIALSLALLSTAAFSQSKSENAPIFTQATYQGDDQIYKDNPLKPGEFYNPILQGCYPDPAITRKGDDYYLVVSSFAMFPGVPIFHSKDLVNWKQIGHVLDRVSQLDVHDTGISMGVYAPGITYNKNNDTFYMITTAFAGGLGNFVVKTKDPMKGWSDPIKLRFDGIDPSIFFDDDGKGYVVHNDAPAKGQELYNGHRVIKVWDYDVEKDQVVPGSDKMIVNGGVDLSKKPIWIEAPHLYKKDGRYFLMCAEGGTGGWHSEVVFVSNSPKGPFIPAGSNPILSQRYLPRDRKNKVDWAGHADLVLGPDNKYYGVFLGIRPNEKDRVNIGRETFILPVDWSGDFPVFENGLVPMEPKLKTPQSVENKTASKEFFPNGNFTYNENFTGSSLDFRWIGLRGPREDFITLTKKGLLIKPFETNVNELKPTSTLFYRQQHNTFSFSTTVDFKPQSEKNLAGIVCLQNEKFNYVFGITTNGKDRYLVLQRTEKGKSIILSSEKISAKGVVNLKVSAKGDQYQFSYSVDNINWINSGTVVSGDILSTNMAGGFTGCLIGLYATASNDAFPKLN
>NZ_CP043329.1|WP_149073622.1|238256_239354_+|endo-1,4-beta-xylanase
MLKFHKSLLFITVLACFIAGIAFKSINRKDVNKGLKSYYTSYFPVGVAVGARNLSGQSAEFIVKNFNSITPENAMKMGPIHPEENRYFWAEADSIVSFAQHHNLKVRGHNLCWHEQTPNWMFKNADGSEVSKEVLLRRLKDHINTVVKRYKGKIYVWDVVNEAIDDDSTKYLRNSQWYKICGEDFIIKAFEYAHEADPEAKLFYNDYNTERPEKTERVYRLVKSLVDKKVPIHGVGLQGHWSIFEPSEQELRNTINKFSSLGLEVQITELDMSVYRWEKERRPKRPDESDEYTAELQQKQAEQYQKVFQIFRDNKDKVTSVTFWNISDRYTWLDNYPVPGRKNYPLLFDTNFQPKQAYWSVVNFK
>NZ_CP043329.1|WP_039449710.1|263078_263462_+|hypothetical-protein
MADKVKFTLEYEIKCSPKILYSFISEPNGLSQWFADDVFIKDHVYTFVWDDGEEQKAKMLSSKESKSVKFAWIDDEPYTFFELEIMKDELTNDVALVITDFALQENLKDRQLIWNIQIENLLSVIGA
>NZ_CP043329.1|WP_039449707.1|263481_264924_+|YjgP/YjgQ-family-permease
MKKVHLLIIKAFIRPFIVTFFIVMFVLLMLFLFKYIDDLIGKGFEWYVILQLLMYAAATNVAMALPLAVLLSSIMTFGNLGENYELVAIKSAGISLQKAMAPLVAMVVGLSIAAFLFSDFMLPVANLKMGSLLYDVRNQKAAFLIEEGIFNNSIPGYSIRVKQKLLTDSGDVLKDIVIYDQSKNNGNTNVLMADEGEMYKTKDEKYLILKLKDGVRYEESNGKGYDPRERLTRFNFKETEQRFDLSSFNFKREDESLFKNNFQMMNLKELDSAEKDTRVRYDSIRMVGAKSLESYYKLYYSTAKYKTAVGKSGLNFKKDGVLAGLDSTQYASAVTSALDNVRYAKDGLETHIFQSEEFMKTIRRYLVEYNRKFTLSVSCLVLFFIGAPLGAIIRKGGLGLPVVVSVIFFLIYHVISTVGEKSVKEGSLSPVMGMWIAIFVLTPLGLFLTYKATVDSALFDADFYKNFFKRFFKKKEKSTL
>NZ_CP043329.1|WP_039449703.1|265058_266264_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II
MLNTIEEAIEDIKAGKIIIVVDDEDRENEGDFLTAARNATPEVINFMAKHGRGLICAPITTDRCRELNLELMVGKNTATFETNFTVSIDLIGHGCTTGISASDRSKTIMALIDPKIKAEDLGRPGHIFPLISKNGGVIRRAGHTEAAVDLAELAGFEPAGVICEIMNEEGEMARLPELLEMAKKLDMKIVSIQDLITYRLRTESLIKKEVSVKLPTEWGDFEMVAFTQVNTGENHLALVKGSWEEDEPILVRVHSSCMTGDIFGSCRCDCGPQLHKAMEMIEQEGKGLIVYMNQEGRGIGLVNKLKSYNLQENGMDTFEANIALGFGMDERDYGVGAQIIRSLGVRKMKLMSNNPTKRAGLIGYGLEVVDNVAIEIESNKHNELYLKAKRDKMGHTIMKER
>NZ_CP043329.1|WP_149073631.1|266292_270711_-|translocation/assembly-module-TamB
MIGTLIFSLQFKPVQTWAAKKAAVFLADELKTRVEIGSLYLKPFKSLVLEGLLVEDLEGDTLLLAPELEVDIDYFAPFSERRIDLDYAELTNAKFFLKSYKDSTTNLTFIINYFDSGVVDTTKKKRPFNFSLNNILIKNLDFRYINYLSEMVYKEGIDYNNIHLWNFSADINDLDTKNHLFKAQINKLRFKEKTGFVLNNLTGALTIDTNSITVENMLLQTPSTTLTDYYSMRFKSFKDFQDFNNKVTVEAHFKNAKVVAKDIAYFAPQLAKMDLVLDVTGTIKGRINNLKARDLTIKAGQATYIKGDFNLRGLPDWDNTFLDLRFDQVYSNKKDIDYILGKATGNKVKAIPAIIDKFGNINFNGQFTGFQNDFIAYGEFKTKLGRLKSDINMKIDKAGIPSYTGNLQAFDFNIGDLTNQPTLNRTSFTVDVKGRDFELNNLYEEIAASVRYFDFKGYRYSNIKVDGTINKQLFDGKVKVNDKNLKLDFNGLANLNPTLPEFKFKAQIRQANLHKLNLYKDTIQIDADFTTDFTGNSLDNIQGNLELSHVKATTKDSSFVIDSVFLRARGIGKDRLLALTSDIGDASIKGQYDLATLPSAFKTVVKKYIPSLKTKIVPPKDQNFEFNIDLKNFDYVSNIFFPQLKIPERGVFNGKFDSKNNLVNLNGYVKTIKYNNMVFNNLIIDQNTNSKSFEAILSLDKVDFSENGLFVQNIVLQNTLKSDSLTFNVKLSDKDAVNQLDLYGLVEFGSDTLAKVSILPSDIVIDNQIWKVEDKASIKFEENKTIIEGFELSNSTQLVAVNGAISASEDDLLEIVIENLQMSSLSQVTKNFGVELKGMMNGTANLSAILGNPNIGADITVDSLRYNRTEIGFVSLSSAYDNEENNINIKASVEKNNKKTTDITGIVDFNSETNNLDLAMNLDQTELILFEPFVKSLITKLKGNISSDLKITGKFSNPQIDGDVRLNNAGFMVNYLKTAYTINDEVNIENSLIRIEDLEIVDAFKNKAIANGIVDLKNPSNPLLDISVKANNFMSLNTTSKDNGIYYGTAFGTGTFTFKGPTDAMNINIKAKTEEGTVFTIPLNNASTIGNNDFITYIAKDTSLNKTKKENFFNGLTMEFELEVGQTSVTNILTEVGNLSGKGDGQLRLRITSLGDFEMFGDYIINEGKFDFTANNVINKTFDIRKGGTIRWTGDPSDANINLNAVYSTRASLLPLYQAAGTTLPDDQRNLRVLAEAEMMLKGSLLNPDIAFNLAFPNNTDIKTRLQGYLDNEDNEAQQVINLVVRNSFNGNSGGGIGFTNNDLLGSGLELAFSKINNIISQSLNIKNLDINVRSQNEIGGSYSFFNNRLRITGNFVNNRYSNDVLNNNLLNSNLNDLTRDVEMSFNINKDGSFVAKSFQRPTNQDLFNLNTDLYVNGFGLVYTQEYDTFKEFIRNTFARGKREAESKENAEDRRKTLSKPIIATPKEEEEN
>NZ_CP043329.1|WP_149073632.1|270793_271813_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MAIILGIESSCDETSASVCIDGVIASNIIANQTIHHQYGGVVPELASRVHQQNIIPAVHQAIVEAKINKNQIDAVAFTRGPGLLGSLLVGTSFAKAFALANEIPLVEINHMQAHILAHFIPNQMEDKKLPQFPFICLTVSGGHTQIVLVKDYFEMEILGETTDDAAGEAFDKTAKILELPYPGGPLIDQYAKTGNPHAYQFPEPQIPGLNFSFSGLKTSILYFIRDNVKQNPNFVQENLADICASVQYRIVSILLNKLKKAAQEQQIKDIAIAGGVSANSGLRTALTGLAQQKGWNVFIPKFEYCTDNAAMIAIAGYYKFLKKDFVGQEIAPLARMPFA
>NZ_CP043329.1|WP_149073633.1|271809_273813_+|hypothetical-protein
MRYFIHQRKLTGLAIVLAGFSLLIFQHLWAYTGHFGFDDLNYAELAHAFFQKQPIWDNTFTFRFGIVIPLGILYWLFGVSDGVSIIFPMLVSLGLLLLVYDNLKGETYKTWIATAILLSNPWITFYSDKIGVDIPITLVILLAITILYKSRFGLYWQKKLVLSGFLLASTVFLGLLTKETIWFLFPLVVFFFFIDLIKLQRIKFWLSALVTLSLFLAVYFYWQYLQFGNWFYRFELIQKYDNTNLCSYDRQPLAIVLNRIGYELFLHFVKEAAFILPVLAVFLCIAKQTFINIRTKENFWLLSAIILILTANFWSISYHSYHPLCVDIRHYLFIMPVSAIAIAHHYKRLFRFWPLIFLLAASMLVIIFDEYWEMKTIAVYQAICLILIFGLMLLYTKHQKYIFLGIALLPLLNVYVQLKSAKAFNYPEQRAVAQQFIKDKKNTTVYAAETQIRLFKYHLGFQLNHFRLVPYDNFEKLEDGYHYWNYHAAYAAGELDFVPPEVNHFSVPEHQLLDTRDMKIWRINKQFLDAELEFYEAKKSPLWTGFVADTVLIKAKDEFGPTFKTMINADVKSINISAKWKLKKNDLKGATVIFTLEEQGKMIFWKPFSIYSDRAVVDNWYVLYKSVRFENFKISKQAELKVYIWNNFKTELEIAEASVSLVRGHKD
>NZ_CP043329.1|WP_149073634.1|273815_274391_+|aminoacyl-tRNA-hydrolase
MKYLIVGLGNIGPEYADNRHNIGFMVLDELAKQENAKFSMLKLAYYTEVSFKGRMLHLIKPTTYMNLSGKAVSYWMKELKIPIENVLIIVDDLAIPFGAIKLKPKGSPAGHNGLKSIEGLLGSNEYSRIKFGISDHFPKGRQADYVLSGFDQDELSDLPTLIERSIAIIKSFVTVGAELTMTNFNNLKLPK
>NZ_CP043329.1|WP_052176804.1|274452_274671_+|hypothetical-protein
MSIQFLSDENGRKLAVQVPIEEWEKIKAIHPDVEYLSNDLPQWQKTLIDKRLETIKVNPNSIKSADDLFLDL
>NZ_CP043329.1|WP_149073635.1|274730_275726_-|aldo/keto-reductase
MQYRKLGDTALELPVITFGAWAAGGWMWGGADDQEAIKAMLAAYDEGVNAIDTAPIYGQGHSEVLVGKAIKELSRDKVQILTKFGMRWDDNKGDFGFKSIDNFGKDIAIYKYAAKESIIKECEDSLKRLGTDYIDLYQIHWPDVTTPIQETMQAVEELIKAGKVRYAGVCNYDVAQMTEAEKYIKLASNQIPYSMVKRDIEQEIVPYCLALDKGILAYSPLERGLLTGKMKPGHVFNEGDHRAGIYFFKDENLVKVDAFLNKIKPLADERNMLVSQIVLRWTLEQPGITIALVGARNAKQAVENAKAARVQLSKEEIKFISNELDKLQLSL
>NZ_CP043329.1|WP_149073636.1|275741_277766_-|TonB-dependent-receptor
MKLHLFILATLVAGTTQAQELDSIKTLNEVKINAYLGEQILISLPATATIINKAQLEQRTQNTLLPALNSISGVKMEERSPGSYRLSIRGSLIRSPFGVRNVKVYYDDFPLTDAGGNTYLNLIDQNTVKGIEILKGPDGSLFGANSGGVVLINSSSSEKTSEFSAIRGSFGLFGQHFGVQNQVKNYEYSFNQAYQEADGYRINSAMRRLFFQTQQKWKYNQNGTVKFSGFYADMNYNTPGGLTAVQLVENPRAARARAEELNTGIYNKSVFLGLSHDYKITNSLRHYIGISGLVTDFKNPFFTNYEYRDENSYALRTYLELKNKETSSIKLQWNLGYEYQRTKTDFINYGNQAGNPTTIRDADEIKNFNEFIFNRFAVELLPELKIEASLSLNFNRFNFRTLPQSPRQDAGDGKFDPTFIPKLALSYLVTPHFSLRALVSKGYSTPTKDEIRPSNRIINTSLNAEEGWNYEVGFRLRTSDERIYADVSAFYYRLDNAIVRRVNASDEDFYVNAGGTNQLGAEIQLNANIIKADARALSIDYYNAITISKFEFRDYFIGSNNFSGNMLTGIPKLNWVNGLNISLFKKLNLFVQHQYNGKTSLNDAETVFADSFHLIQSKLNYIVPFNNVKLHITFGVDNLLNEKYSLGNDINAFGNRYFNPAATRNYYAGLALKW

Crispr_ID: NZ_CP043329_3

• CRISPR_ID: NZ_CP043329_3
• CRISPR_location: 1152814-1153073
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP043329_3

Consensus_repeat	Method
ACTTTTGAATTTTTANTTTT	CRT

spacers of NZ_CP043329_3

>3.1|1152834|46|NZ_CP043329|CRT
TACTTTTCAACTCAACAGTTACTCTTAACTTATTACGCAAGTAAGC
>3.2|1152900|46|NZ_CP043329|CRT
AAAAGCACTTTTGAATTTTCACTTTTGACTTTTTAATTTAATAAGC
>3.3|1152966|34|NZ_CP043329|CRT
GAATTTTTAATTTAATAAGCACTTTTGAATTTTT
>3.4|1153020|34|NZ_CP043329|CRT
GAATTTTTACTTTTGAATTTTTAATTTAATAAGC

CRISPR arrays and Neighbor proteins around NZ_CP043329_3

CRISPR arrays

The CRISPR arrays of NZ_CP043329_3

>merge|NZ_CP043329|3|1152814-1153073|CRT
CAATTTGAATTTTTATTTTTTACTTTTCAACTCAACAGTTACTCTTAACTTATTACGCAAGTAAGCACTTTTGAATTTTTACTTTTAAAAGCACTTTTGAATTTTCACTTTTGACTTTTTAATTTAATAAGCACTTTTGAATTTTTACTTTTGAATTTTTAATTTAATAAGCACTTTTGAATTTTTACTTTTGAATTTTTACTTTTGAATTTTTACTTTTGAATTTTTAATTTAATAAGCACTTTTGAATTTTCAATTAA

>NZ_CP043329|3|1|1152814-1153073|CRT
CAATTTGAATTTTTATTTTT	TACTTTTCAACTCAACAGTTACTCTTAACTTATTACGCAAGTAAGC
ACTTTTGAATTTTTACTTTT	AAAAGCACTTTTGAATTTTCACTTTTGACTTTTTAATTTAATAAGC
ACTTTTGAATTTTTACTTTT	GAATTTTTAATTTAATAAGCACTTTTGAATTTTT
ACTTTTGAATTTTTACTTTT	GAATTTTTACTTTTGAATTTTTAATTTAATAAGC
ACTTTTGAATTTTCAATTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149074168.1|1148098_1149904_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|226664
NZ_CP043329.1|WP_149074172.1|1151885_1152608_+|diphthine--ammonia-ligase	unknown	unknown	gnl|CDD|238952
NZ_CP043329.1|WP_039453719.1|1158921_1159446_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074174.1|1154549_1155467_-|amidinotransferase	unknown	unknown	gnl|CDD|227211
NZ_CP043329.1|WP_149074170.1|1150688_1151192_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|376754
NZ_CP043329.1|WP_149074176.1|1159453_1159834_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP043329.1|WP_149074178.1|1162165_1163356_-|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234813
NZ_CP043329.1|WP_149074165.1|1145437_1145923_+|cytochrome-C	unknown	unknown	gnl|CDD|379587
NZ_CP043329.1|WP_149074171.1|1151200_1151893_+|NAD-dependent-deacylase	unknown	unknown	gnl|CDD|238703
NZ_CP043329.1|WP_149074167.1|1147237_1147513_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074180.1|1164966_1165575_+|HAD-hydrolase-like-protein	unknown	unknown	gnl|CDD|372595
NZ_CP043329.1|WP_149074179.1|1164226_1164970_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_039453705.1|1163570_1164224_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP043329.1|WP_168199389.1|1147074_1147251_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074175.1|1157050_1158436_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl|CDD|235392
NZ_CP043329.1|WP_149074164.1|1144646_1145441_+|inositol-monophosphatase	unknown	unknown	gnl|CDD|238817
NZ_CP043329.1|WP_149074177.1|1159843_1160266_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074181.1|1165649_1167245_+|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|143477
NZ_CP043329.1|WP_149074169.1|1149939_1150518_+|hypothetical-protein	unknown	unknown	gnl|CDD|182616
NZ_CP043329.1|WP_149074166.1|1145943_1147086_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149074168.1|1148098_1149904_+|TonB-dependent-receptor	gnl|CDD|226664	COG4206, BtuB, Outer membrane cobalamin receptor protein [Coenzyme metabolism].	9.48472e-68
NZ_CP043329.1|WP_149074172.1|1151885_1152608_+|diphthine--ammonia-ligase	gnl|CDD|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	1.17987e-53
NZ_CP043329.1|WP_149074174.1|1154549_1155467_-|amidinotransferase	gnl|CDD|227211	COG4874, COG4874, Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown].	1.15484e-110
NZ_CP043329.1|WP_149074170.1|1150688_1151192_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	gnl|CDD|376754	pfam02283, CobU, Cobinamide kinase / cobinamide phosphate guanyltransferase. This family is composed of a group of bifunctional cobalamin biosynthesis enzymes which display cobinamide kinase and cobinamide phosphate guanyltransferase activity. The crystal structure of the enzyme reveals the molecule to be a trimer with a propeller-like shape.	4.65581e-69
NZ_CP043329.1|WP_149074178.1|1162165_1163356_-|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl|CDD|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP043329.1|WP_149074171.1|1151200_1151893_+|NAD-dependent-deacylase	gnl|CDD|238703	cd01412, SIRT5_Af1_CobB, SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. CobB is a bacterial sirtuin that deacetylates acetyl-CoA synthetase at an active site lysine to stimulate its enzymatic activity. .	1.15854e-97
NZ_CP043329.1|WP_149074165.1|1145437_1145923_+|cytochrome-C	gnl|CDD|379587	pfam14376, Haem_bd, Haem-binding domain. This domain contains a potential haem-binding motif, CXXCH. This family is found in association with pfam00034 and pfam03150.	6.46208e-63
NZ_CP043329.1|WP_149074180.1|1164966_1165575_+|HAD-hydrolase-like-protein	gnl|CDD|372595	pfam13419, HAD_2, Haloacid dehalogenase-like hydrolase.	7.29593e-10
NZ_CP043329.1|WP_039453705.1|1163570_1164224_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	8.32263e-110
NZ_CP043329.1|WP_149074175.1|1157050_1158436_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl|CDD|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP043329.1|WP_149074164.1|1144646_1145441_+|inositol-monophosphatase	gnl|CDD|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	3.87928e-98
NZ_CP043329.1|WP_149074181.1|1165649_1167245_+|PDZ-domain-containing-protein	gnl|CDD|143477	cd07561, Peptidase_S41_CPP_like, C-terminal processing peptidase-like; serine protease family S41. Bacterial protease homologs of the S41 family related to C-terminal processing peptidase (CPP). CPP-1 is believed to be important for the degradation of incorrectly synthesized proteins as well as protection from thermal and osmotic stresses. CPP is synthesized with an extension on its carboxyl-terminus and specifically recognizes a C-terminal tripeptide, but cleaves at variable distance from the C-terminus. The CPP active site consists of a serine/lysine catalytic dyad. Conservation of these residues is seen in the CPP-like proteins of this group. CPP proteins contain a PDZ domain that promotes protein-protein interactions and is important for substrate recognition however, most of CPP-like proteins only have an internal fragment or lack the PDZ domain.	2.19395e-45
NZ_CP043329.1|WP_149074169.1|1149939_1150518_+|hypothetical-protein	gnl|CDD|182616	PRK10647, PRK10647, ferric iron reductase involved in ferric hydroximate transport; Provisional.	0.00256272
NZ_CP043329.1|WP_149074176.1|1159453_1159834_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00437165

Protein sequences

>NZ_CP043329.1|WP_149074172.1|1151885_1152608_+|diphthine--ammonia-ligase
MNRKPCIFNWSGGKDSALALYYLLQNPDYEVKYLVTTINDSLNRISMHGVRESLLLQQAASLGIPLYQIRLPEMPGMSVYDEIMHHHLTILKEEGITHSVFGDIFLEDLKAYREAKLQEVGMEAVFPLWQKDTKKLIHDFLNLGFKTVIACTQENLGAYVGKVIDIALINSLPENIDPCGENGEFHTFVFEGPIFKNAIPYTLGEKVFKSYPTPKNEDDVCFTKDDKPKNLGFWYVDLVG
>NZ_CP043329.1|WP_149074171.1|1151200_1151893_+|NAD-dependent-deacylase
MKKKIIVLTGAGISAESGLKTFRDADGLWEGYAIEDVATPEAWQRNPVLVQQFYNERRKGVLAAEPNPAHFALKKLEEKFEVLIITQNIDDLHERAGSSNIMHLHGEIVYARSSQNPALLYKLDKPEIEMGELCELGSQLRPHVVWFGEAVPMITKAMHEMPLADIVILIGSSLAVYPAAGLLELARKEVPVYVIDPKIPEVRISNPLIKIEEKASLAVPLLVEKLLKHE
>NZ_CP043329.1|WP_149074170.1|1150688_1151192_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase
MIYYISGGARSGKSSYAQNLALSLTNKPVYLATARNWDKDFEKRIIRHQQDRDERWENIEEEKYPAKIDFTGKVVVIDCVTLWLTNFFVDTKYNVEASLEQIRQAFDDLTQQEATFIIISNELGMGLHADTESGRKFTDLQGWFNQYIAKKADKAIFMVSGLPLTLK
>NZ_CP043329.1|WP_149074169.1|1149939_1150518_+|hypothetical-protein
MSLNKINVRNWVLVVMILAAAATRFFSLGEQTAWSNFTPVGAIAMFGGTYFTNKYKAYLVPLITLFISDIFVTYSYTGEFTLFYNGFIWVYICFVAMVFIGSLIKTVNVNTVLLGSLAGVLIHWLVTDIEPWLGGTLYNKDITGYYQSLIAAIPFEKNLLLGNLVFGAVLYGGFELAKSKFTILKSQKELAY
>NZ_CP043329.1|WP_149074168.1|1148098_1149904_+|TonB-dependent-receptor
MVTASRSPKKISDIGKMVRVISREEIERSQGRTLPELLNTVPGLNVTGSGSALGEVKSVYLRGASSANTLILIDGIPVNDASGISGEYNLAAIAIDQIERIEVLKGASSTLYGSDAVAGVINVITKKGEGKLKTNALLSGGSYNTYKQAVGLNGNINKTAVALNFSNLDSKGFSSAQPLNAASLFEKDKFSQQGLSLNLSQYLNNTVKILGGLQLNNNKSGLDGGAFQDNTNYNYNKVALLGNIGLNVALRKGNLSLIASQNNVSNKFNNNGANSYYKGSITNVEGIFSYKVNNFLDLTSGANYKYSATDQFSGFGAPLTAGNANNNIASLFTSLFFNVKDVFRMELGGRYNNHSAFGDNFTYTFNPSVLLFNSIKVYGNISSAFRVPSLYQLTSEYADPNGLNPETSFNYEAGFSTDLFQNKLNINTSVFFREIDDVIDFGSRADGSFGYLNQNQQNDEGIETEIGFKPSDKLSISAFYAYVYGRVIKSPGTPGAFNLSRRPVNSSGANVSYNLNKNLSFSLLYKWTDSRRDIYYDTDFNEQNVVLTSYHKFDAYVQYKTKKNVTLFADVKNLFDARYNDFAGYNTMGTNFNAGISFLFQ
>NZ_CP043329.1|WP_149074167.1|1147237_1147513_-|hypothetical-protein
MKINIASNVKALKSKSALQTNFNHHQHRLSEELNKGKQHVLYTSLLYVLSILSIGSWIISLKLLPFGDMFQFLLGAAVLTVNLLIFRHAKI
>NZ_CP043329.1|WP_168199389.1|1147074_1147251_-|hypothetical-protein
MLKFKAMTFDEPQANRKDWKKQKAKRDLLVKRNDEIANKPVSIFETDNESSNKKKLKK
>NZ_CP043329.1|WP_149074166.1|1145943_1147086_+|hypothetical-protein
MQYSPKYQSAKIVAPKIEEHFLHHIALASHKGEQDIATIPQVSIIEAIIDVCFWASFRSEEGKYPRISLAFLSPEQALHPVVFQEKLSLNAYVLSKLAPGIEGAGIHLGVWYQDGELYVWGSTTSIPDYCFVLDVSEPGLLVIKHKRINGYGKFTNVVILKGDEIKIVNEDSGMLPDSPQILKSLLGFTAPYLRNDTANILIQLAVFMRSHGRGGTLLLTPSADEQWKSSLIQPFHYQLNPPFEGLANLILKDGANISESLWVSKLKREVDHIAGFTAIDGATIINDKYELLAFGVKIGKREGNTSVKKIAFIEPVIGGEASLLEVSRLGGTRHLSAAQFVFDNHDCIALVASQDGYFTVLSWSESMKCVQAHRIETLLF
>NZ_CP043329.1|WP_149074165.1|1145437_1145923_+|cytochrome-C
MKKKILLGLLAVLVIIQFIKPEKNVSSTPSVNSIHNKFPANEETMQILKTACNDCHTNNTVYPWYAHIQPVAWWLDSHVDDGKKHLNFDEFLTYKLKKQDHKLEELIESQEDHWMPLDSYTWIHKDAKLDEKQRLALVNWAKETRLKIQSDPAFALEEDKK
>NZ_CP043329.1|WP_149074164.1|1144646_1145441_+|inositol-monophosphatase
MLNYQELCDEVIRIAKEAGAFIRKESALFQSSKIEYKGTNDMVSYVDKTSEEMIISALAKVLPGSGFIAEEGEHQKAETFNWIIDPLDGTTNFIHGIPAFAVSIALQEGDELVLGVVYEIGKDECFYAWKGSAAFLNGKEIKVSASTKVADSLLATGFPYYDFTRKDAYMALFGDLIQSCHGLRRIGAASVDLVYTACGRFDAYFEYNLKPWDIAAGMFIVQQAGGENFDFEGGKNALKNCDIVSTNGHISQELLTVINKYFKS
>NZ_CP043329.1|WP_149074174.1|1154549_1155467_-|amidinotransferase
MQTTSQILMIRPVAFALNQQTLASNAFQDAQTEQEEVQEKALKEFDAFVEVLKANHIHINVIQDTLEPHTPDAIFPNNWISFHENGEIFLFPMLAENRRQERRADIIESLKKHYQVKILTDLSFYEKEHKFLEGTGSMVLDRENKIAYACLSARTHEDVLKEFCQRSGYEAIMFHAEDAKGIAIYHTNVMMCMATKFAIVCMDAVKDLKEQQIIKESLSKTGKLLIEISLAQMNQFAGNMLELQNTHGEHLLVMSRSAFKSLTSKQIQEIEQFVNILNVPLETIEKNGGGSARCMIAEVHLPSLS
>NZ_CP043329.1|WP_149074175.1|1157050_1158436_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MSLHQEETIVALATPAGIGAIGVIRLSGPEAISITNKVFYGKNLEAQDSHTIHFGTLRDGDFIIDEVLVSLFVAPKSYTKENVVEISCHGSDYIIASIIKLMIKNGARAAKAGEFTLRAFLNGGLDLSQAEAVADLIASSSKSAHQLALQQMRGGFSNELKNLREQLIHFASMIELELDFSEEDVEFANRDQLKQLILAINKVVSRLIQSFEMGNVIKNGVPVVIAGKPNVGKSTLLNVLLNEERAIVSDIAGTTRDTVEDEITLKGVRFRFIDTAGIRETADIIEAKGVERTFEKIKSSAIVLYLFDPRETSLTELKAIMDDLHQVIQENNSKLLLVANKTDETQVNNALTGFESLGEILNISAKEKYNIQLLEDELLKAANLSQINKDEVIVSNIRHLEALQKTEASLSRVLHGIDNPVTSDFLAMDIKQALYYLGEITGTVTTDDLLENIFSKFCIGK
>NZ_CP043329.1|WP_039453719.1|1158921_1159446_+|hypothetical-protein
MNNFVQIKKVAQYDKVSYYSVTINSETTSLFEQFIATHTANNKEKLNHILAWLQEIGIKYGAQTYLFRPEAYLSDTSALPPTGKDKEPTYIENGETESNNLRLYCFRLNENVVVLYSGDLKTADKAQDCINVKSHFLLANKLTRALENSIKENEVYWNEDCTDIIFDSDLEIAY
>NZ_CP043329.1|WP_149074176.1|1159453_1159834_+|helix-turn-helix-transcriptional-regulator
MENNIISNWLKENGDPSIRKATEINLAIATKINNILQAKSLKAVDLAVKLNKNQSEVSKWLTGMHTFTTKTLAKISLALEEEIIFTEPKTKNIYFTVYKNENVNDGTEYETSEILASSIDLDRKIS
>NZ_CP043329.1|WP_149074177.1|1159843_1160266_+|hypothetical-protein
MIDPLKIHLTNIVKLTETISSDCLNRSVEEMEMDISHQMMHNLEKKKVKLNIQIAFLCKDKPDQQLAAFSYDFFYTIDDLEVHYQLTNEKPLFDGLFVSTLLGISYSTIRGILFQQLTEAPLKNILLPVINVPDLLKSKN
>NZ_CP043329.1|WP_149074178.1|1162165_1163356_-|ADP-forming-succinate--CoA-ligase-subunit-beta
MNIHEYQGKQILKSFGVRIQEGIVADTPEQAVEAAKKLKEDFGSDWVVVKAQIHAGGRGKGGGVKLAKNLDEVKQRASDIIGMQLITPQTGAEGKKVNKVLIAQDVYYPGESETKEFYVSVLLDRSRGRNIIMYSTEGGMDIEEVAEHTPHLIFKEEIDPKVGLQGFQTRKIAFNLGLSGNAFKEMTKFIAALYKAYEATDSSMFEINPVLKTSDDKILAVDAKVDLDDNGLFRHPDYAAMRDTSEEDPTEVEASESNLNYVKLDGNVGCMVNGAGLAMATMDIIKIAGGEPANFLDVGGTANATTVKAAFNIILKDPNVKAILINIFGGIVRCDRVAQGVIDAYKEIGDIRVPIIVRLQGTNAEEAKKLIDESGLKVFSAILLKEAADLVSEVLA
>NZ_CP043329.1|WP_039453705.1|1163570_1164224_+|ABC-transporter-ATP-binding-protein
MLKAQSIKRKFGDLSILKGVDIDVAKGEIVSIVGASGAGKSTLLHIIGTLDKADEGSVEIDGIAINQLNARTLSRFRNKNIGFIFQFHHLLPEFTALENICIPAFIAKTSKNEAEKRAMELLAILGLADRAHHKPAALSGGEQQRVAVARALINKPALILADEPSGNLDSANAKELHQLFFSLRDQFNHTFIIVTHNDELAEMSDRKITMKDGYIFS
>NZ_CP043329.1|WP_149074179.1|1164226_1164970_+|hypothetical-protein
MKKTLITTASNATAYQLAYHLPHHEILFADTKDQKLIIPEGNKLSFAHELLSLCLDLDITLVFPLKLSEQKALAEAKILFEEYGITLALPDLIQAQKINPLAHLYPEQVINYQTVTDYASFSKAVLSLGYPDKQIAIGHHEGVGELIIIQDDKKSDIFSGIKTMPFTLAGKVLNQNPFTAIHLCALEGDMQIVRFIKLEDDLIYVNDVSEEIKKLIESLVSHLSSLGFYEMICSQGKIIRLNLVAVV
>NZ_CP043329.1|WP_149074180.1|1164966_1165575_+|HAD-hydrolase-like-protein
MISYSDLDADKKAFIFELDDVLIPEKDYDLQVYYLFANFVEYLETFPPAQDVVDFAKKRYEIYGKEDMFKALQEAFAIPVKYEENLNLLFTNARLPLKLLLYKEVLELLQEITINRKELYILTSGNPVTQLNKITQTEWNGLEKYLKVYFVDEFEPKPSFTSLDFLLEENKLNKSDVTYIGKNSLDEQFAINAGVSYQAVLS
>NZ_CP043329.1|WP_149074181.1|1165649_1167245_+|PDZ-domain-containing-protein
MLKRVYAIAFIIIIGFASCKKDKATTDNNKPTPTTIRAELTKDSIFLYAKQVYLWNDAIPDYSAVKPRNFNSSSNQLDNFNSLLFDITQYSRNPNNGNRPYEYWDDYPNEPKFSYIEDLVASGQIAIVNPKKSSVNLNGEGNDTGLNIGFYGNGNTAFRRDYFLIIRYVNENSSAADKKLNRGDTILTINGKTYGANFDQESDEVFDRLELDNIIVTGKKRGTGTSFSFTLNKTKYTASPILKDTVFTETGGKKVGYFAYARFSDETNSIPALNAVFDKFNTAGVTDLIVDLRYNGGGFVSTAEHLVNLIIPTQHNGKKMFSEFFNSTMREGKATILKNQPRRDQNGNITRGNYFDNTDYSVAGNTTNISKISGLANVNRVVFITGPGTASSSELVINSLKPYLGANLKIVGEQSYGKPVGFFPIRIDKYDVYFSMFETQNSLGQGAYYDGFVPDFNTGFDDAGKSFGDKNDLAVSQAINFIKNGSFSSSNVANTKGASVSSTSTNNMKSLDPKDLFSREFKGMIDYPGRR

Crispr_ID: NZ_CP043329_4

• CRISPR_ID: NZ_CP043329_4
• CRISPR_location: 1851341-1851440
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP043329_4

Consensus_repeat	Method
CTAACTAATAACTAACAACCTAACCA	CRISPRCasFinder

spacers of NZ_CP043329_4

>4.1|1851367|48|NZ_CP043329|CRISPRCasFinder
TCTAACCAACTAACACCAACAACCTAACTAACTAACTAACTAACTAAC

CRISPR arrays and Neighbor proteins around NZ_CP043329_4

CRISPR arrays

The CRISPR arrays of NZ_CP043329_4

>merge|NZ_CP043329|4|1851341-1851440|CRISPRCasFinder
CTAACTAATAACTAACAACCTAACCATCTAACCAACTAACACCAACAACCTAACTAACTAACTAACTAACTAACTAACTAACTAACTAACAACCTAACCA

>NZ_CP043329|4|2|1851341-1851440|CRISPRCasFinder
CTAACTAATAACTAACAACCTAACCA	TCTAACCAACTAACACCAACAACCTAACTAACTAACTAACTAACTAAC
TAACTAACTAACTAACAACCTAACCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149074589.1|1856191_1856848_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|273138
NZ_CP043329.1|WP_149074584.1|1851473_1852673_-|aminoacetone-oxidase-family-FAD-binding-enzyme	unknown	unknown	gnl|CDD|367519
NZ_CP043329.1|WP_149074579.1|1846625_1846820_+|DUF4287-domain-containing-protein	unknown	unknown	gnl|CDD|379478
NZ_CP043329.1|WP_149074585.1|1852767_1853352_+|NAD(P)H-quinone-oxidoreductase-subunit-3	unknown	unknown	gnl|CDD|180638
NZ_CP043329.1|WP_149074582.1|1849207_1849900_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|379312
NZ_CP043329.1|WP_149074580.1|1846925_1848644_+|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NZ_CP043329.1|WP_039447418.1|1849990_1850464_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074587.1|1855002_1855515_+|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl|CDD|376377
NZ_CP043329.1|WP_149074581.1|1848729_1848936_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074588.1|1855511_1856075_-|YqgE/AlgH-family-protein	unknown	unknown	gnl|CDD|376864
NZ_CP043329.1|WP_149075881.1|1845266_1846562_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|236722
NZ_CP043329.1|WP_149074583.1|1850658_1850994_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl|CDD|367091
NZ_CP043329.1|WP_039447423.1|1850983_1851214_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_026903629.1|1853348_1853831_+|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_CP043329.1|WP_039447413.1|1848937_1849150_-|DUF3820-family-protein	unknown	unknown	gnl|CDD|378970
NZ_CP043329.1|WP_149075882.1|1857385_1858534_+|NADH-quinone-oxidoreductase-subunit-D	unknown	unknown	gnl|CDD|180385
NZ_CP043329.1|WP_149074578.1|1844516_1845128_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074590.1|1856844_1857345_+|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|376317
NZ_CP043329.1|WP_149074586.1|1853863_1855003_+|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl|CDD|235674
NZ_CP043329.1|WP_149074591.1|1858613_1859711_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|379142

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149074584.1|1851473_1852673_-|aminoacetone-oxidase-family-FAD-binding-enzyme	gnl|CDD|367519	pfam03486, HI0933_like, HI0933-like protein.	5.91274e-158
NZ_CP043329.1|WP_149074579.1|1846625_1846820_+|DUF4287-domain-containing-protein	gnl|CDD|379478	pfam14117, DUF4287, Domain of unknown function (DUF4287). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 70 and 180 amino acids in length.	2.66323e-06
NZ_CP043329.1|WP_149074585.1|1852767_1853352_+|NAD(P)H-quinone-oxidoreductase-subunit-3	gnl|CDD|180638	PRK06602, PRK06602, NADH:ubiquinone oxidoreductase subunit A; Validated.	2.13958e-43
NZ_CP043329.1|WP_149074582.1|1849207_1849900_+|methyltransferase-domain-containing-protein	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.04358e-12
NZ_CP043329.1|WP_149074580.1|1846925_1848644_+|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP043329.1|WP_149075881.1|1845266_1846562_+|DEAD/DEAH-box-helicase	gnl|CDD|236722	PRK10590, PRK10590, ATP-dependent RNA helicase RhlE; Provisional.	1.44771e-161
NZ_CP043329.1|WP_149074590.1|1856844_1857345_+|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|376317	pfam00329, Complex1_30kDa, Respiratory-chain NADH dehydrogenase, 30 Kd subunit.	1.55089e-59
NZ_CP043329.1|WP_026903629.1|1853348_1853831_+|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	4.74121e-99
NZ_CP043329.1|WP_149074588.1|1855511_1856075_-|YqgE/AlgH-family-protein	gnl|CDD|376864	pfam02622, DUF179, Uncharacterized ACR, COG1678.	2.62022e-47
NZ_CP043329.1|WP_149074587.1|1855002_1855515_+|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl|CDD|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	2.69806e-89
NZ_CP043329.1|WP_149074583.1|1850658_1850994_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl|CDD|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	3.90592e-26
NZ_CP043329.1|WP_039447413.1|1848937_1849150_-|DUF3820-family-protein	gnl|CDD|378970	pfam12843, QSregVF_b, Putative quorum-sensing-regulated virulence factor. QSregVF_b is a family of short Pseudomonas proteins that are potential virulence factors. The structure of UniProtKB:Q9HY15 a secreted protein has been solved and deposited as Structure 3npd, from pfam13652. It is predicted that these two adjacent proteins form a single transcriptional unit based on the prediction that together they interact with their adjacent protein PotD, which is the putrescine-binding periplasmic protein in the polyamine uptake system comprising PotABCD. These two adjacent proteins are predicted to be quroum-sensing-regulated virulence factors.	4.36066e-37
NZ_CP043329.1|WP_149075882.1|1857385_1858534_+|NADH-quinone-oxidoreductase-subunit-D	gnl|CDD|180385	PRK06075, PRK06075, NADH-quinone oxidoreductase subunit D.	7.16737e-174
NZ_CP043329.1|WP_149074589.1|1856191_1856848_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	9.62326e-122
NZ_CP043329.1|WP_149074586.1|1853863_1855003_+|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl|CDD|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	2.31254e-149
NZ_CP043329.1|WP_149074591.1|1858613_1859711_-|trypsin-like-serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	3.3077e-28

Protein sequences

>NZ_CP043329.1|WP_039447423.1|1850983_1851214_-|hypothetical-protein
MKVLSLKLDDEIFNEAEEITHELHIARNRYINEAVRIYNLVQKKRLLKKQLAKESALTSKESMDVLHEFERLLDEN
>NZ_CP043329.1|WP_149074583.1|1850658_1850994_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MKIKQFDIWLADLNPSRGTEPGKIRPVVVIQTDLLNDIHPSTIICPITTNVQQDIQILRVHLNENQLDKLSDILVDQIRAIDNKRLMSKLGELTQNQKEKLKANLRIVLDI
>NZ_CP043329.1|WP_039447418.1|1849990_1850464_+|hypothetical-protein
MAKASISVIQALLKTVENLEKGAAYQWGHMGSCNCGNLAQVITNRDKAEIHKSAMRSRHGDWNEQLIDYCPTSGLPIDHIIDEMVAFGFTRADLAHLEKLSDPQVLRQLPASHKYLKHNQKADVILYLKTWVKVLENELIDTISLEDVNKGKELVTV
>NZ_CP043329.1|WP_149074582.1|1849207_1849900_+|methyltransferase-domain-containing-protein
MNDVYGDFLKDYLDKGKTSTIWLHNNYAEAEEMPAEVFFRKDYEITDLEAFALRQCKGKVLDIGAGAGAITLILQKRGFDVTALEISPGAAEVMQKRGVQKIINTNIFDYQDEQYDTLLLMMNGIGFCQYLDEIERFLHHAKKLLKPEGQILFDSSDVLYLYENKKYEDDGYYGEIDYQYEYKGKKGDWFTWIYVARDIMKEIATKCGFQMEVLFDDGSDQYLARLSLKS
>NZ_CP043329.1|WP_039447413.1|1848937_1849150_-|DUF3820-family-protein
MNPEILLDLVKVRMPFGKYKDRILCDLPVSYLEWMYTKGWPAGKLGQQLATIYEIKINGLEYLLKPLRNK
>NZ_CP043329.1|WP_149074581.1|1848729_1848936_+|hypothetical-protein
MQNSVLEITEQEYLIKLNKQEFDLSFIHALLKRIQSEKAFFSKIWDDDDIIAKGRFLEERDIDYLSEK
>NZ_CP043329.1|WP_149074580.1|1846925_1848644_+|lysine--tRNA-ligase
MSILSEQEIQRRQSLQELRNLGINPYPAEAFEINANALDITSNYERDKTSYKNISLAGRIMTRRIMGNASFVELQDATGRIQAYIRRDDVCPEEDKTLYNTVFKKLLDIGDYIGVTGFVFTTQTGEISIHVTEFKVLSKSLKPLPIVKRDDDGNVYDGFTDPEMRYRMRYVDLTVNPEFKEIFKTRSKVISTMRNYFDSQGWMEVETPILQAIHGGAAARPFNTYHNTLDMPLFLRIANELYLKRLIVAGFDGVYEFGKMFRNEGMDRTHNPEFTSMEIYVAYKDYIWMMSMVEECLEKVTTAIHGKTTIKVGNDEIDFAGPYEKLSMYDSIKKYTGIDVSQMNEQQLIDTCKSLNIEVDASMGKGKLVDAIFGEKVEHNLIQPTFITDYPIEMTPLAKKHRTTEGLVERFELFVQGKEIANAYSELNDAIDQKERFEDQLTLAARGDDEAMAMDDDFIRALEYGMPPTAGLGIGIDRLVMLMTNQSSIQEVLFFPQMRPEKKAKVTTDEDFVTAGIPAAWVQVIRKMGINTIEDLKAANPNKVFNDLGGMRKKLKLDLTMPQKEEVMEWFK
>NZ_CP043329.1|WP_149074579.1|1846625_1846820_+|DUF4287-domain-containing-protein
MNQTTETLMTAIEENTGHPLEHWIEIIRKSGKPDCQAITNFLIEEHQLNPVLAELIAQKAKGSH
>NZ_CP043329.1|WP_149075881.1|1845266_1846562_+|DEAD/DEAH-box-helicase
MSFDELDLINPIKKALQTEGYTKPTPIQAQAIPLVLDGNDLLGCAQTGTGKTAAFAIPIIQLLHNSSHQQAKGTRAIRALIVTPTRELAIQIADSFAAYGKNTPLKYAVIFGGVGQKAQTDALAKGVDILIATPGRLLDLMNQRYISLKSINLFVLDEADRMLDMGFIHDVKKLIAALPAKRQSLFFSATMPPVIQKLASEILKNPVKVEVTPESSTADTINQFVYMVDRDNKNKLLIHILEDKNIKTALVFTKTKHGADKVVKMLLNHGIKAAAIHGNKSQNARQRALEEFKSHKIRVLVATDIAARGIDVDDLAYVVNYEIPNIPETYVHRIGRTGRAGANGTAFSFCEIDEKEFLQDIQKIIGKTIPKAEENPFPMTKFTAAPSTKKGGKSGRSKSAAPHKAAQGNAKNNTAQTGKKKFFRKRKETNS
>NZ_CP043329.1|WP_149074578.1|1844516_1845128_+|hypothetical-protein
MENHKEIIPKQQEGIATDIKESITLSGSEEAIQFYDIAVNRLKDVNHWHLLTKHTGTKFTLRDKNGFEVKRQVVLGDYFQINIPFPGLDSGKGYDWVQVKELKEENNQQQDEQTFSMLVKPAHPPFEKETAHFFDAEASSTFSVLRNGTKITALVHGRNEKPNTFVHSLAGKIRNIIVALGSFLGFSYFQWKSLVKGLLSDNE
>NZ_CP043329.1|WP_149074584.1|1851473_1852673_-|aminoacetone-oxidase-family-FAD-binding-enzyme
MLETKYDAIIIGGGACGLMCAVQAGYLGKKTLILEKNAQVGAKILISGGGRCNYTNYYTTAQNFISENEHFCKSALSQWTVDDTISFFETYGITGQEKTLGQLFPTSNKAKDIVEVFKQICDDFGQDIYLNSHVLAVEKLDELFKITFERNGKTETLYSFKVVMASGGLPIAKMGATDFSLKIAKQFGLQVVQTAPALVPLTITGKDADWFAHLSGNSMPAVVSNDEISFEENILFTHWGLSGPAILQISSYWRPGQSIVIDLLPHQNIQELIEQERSANGKKLLANYLALFYTRKFIDALSDILPTHKNLASLTKDDFTAINEFIHHFKVKPAGDKGYDKAEVMRGGVDTNELSSKTLEAKKVPGLYFGGECVDVTGWLGGYNFQWAWASGFVIANSV
>NZ_CP043329.1|WP_149074585.1|1852767_1853352_+|NAD(P)H-quinone-oxidoreductase-subunit-3
MEEYSQISAFGKVLIFLIMGIVFVMLAFITSKIIAPNKPNPEKNSSYECGEEVIGSSWIQFNSRFYVIALIFLLFDVEMVFIFPWAIVFSDATLIAQDQRWGWLSFTEMLIFISILLLGLVYVWRKKDLDWIKPVLKLPTVDTKIPLSAYQAINEAKYQPGLKNKQQENSSVVKENNIETENIKPKFVPRFKKS
>NZ_CP043329.1|WP_026903629.1|1853348_1853831_+|NADH-quinone-oxidoreductase-subunit-B
MSLEQQLENGGVVVTKLDDLLNWARLSSLWPLSFGIACCAIEMMGSMASNYDLDRFGVFPRPSPRQADVIIIAGTVTFKMAERIKRLYEQMPEPKYVISMGSCSNCGGPYWEHGYHVVKGVDRIIPVDIYVQGCPPRPEALIGGILELQKKISTQSLSTI
>NZ_CP043329.1|WP_149074586.1|1853863_1855003_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKSNITQTRLGILGGGQLGRMLIQEAINFNLSISILDPDANAPCKNICDYFEVGSISDYETVYNFGKNLDLLTIEIEKVNIEALEDLEKEGVTVFPQPRIIRLIQDKGLQKQFFKENDIPTSEFQLIANKEQLLTDKIPFPYIQKLRKDGYDGKGVVKIVDESDLNKAFEQASIVEKWIDFEKEIAVIIARNENGQTKTFPLVEMDFNKEANLVEFLISPSTYNFEIQQKADKIARDIADCLNIVGLLAVEMFVTKNGEILVNELAPRPHNSGHHTIEGNVTSQFQQHLRAILNLPLGSTASIANAVMINLLGEAGYEGPAEYEGLKEVLQKEGVYVHLYGKVFTKPFRKMGHVTIVDQDRNAAIEKAQFVKEKLKVKS
>NZ_CP043329.1|WP_149074587.1|1855002_1855515_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MYKPKVGIIMGSRSDLPIMEEAANVLKELGVAYELTVVSAHRTPERMFEYANKAAERGLKVIIAGAGGAAHLPGMVASITTLPVIGVPVKSSNSIDGWDSVLSILQMPNGIPVATVALNAAKNAGILAAQILATADDHLAQQVAKFKNDLKAKIEESAELLKSEGYPSAF
>NZ_CP043329.1|WP_149074588.1|1855511_1856075_-|YqgE/AlgH-family-protein
MLSKVLPKVGDLLISEPFMLDENFKRSVVLLTERGDEGDVGYVLNHKSNLLLKDVVADCWDANFLIHIGGPVANGTLNFIHCCPDKIPGGTPIGKDLFWGGDFETLKLQINSYNITESEIKFFIGYSGWDKGQLVAEINENSWIVSDQYNPAMIFEYSDKNIWKEAILNLGVKYAHVANFPENPEWN
>NZ_CP043329.1|WP_149074589.1|1856191_1856848_+|pyridoxamine-5'-phosphate-oxidase
MSEQKLNLKDLRQDYRSAFLLEEDIEKTPLKQFEKWFKDALKAEILEPNAMTLATASREGIPSARIVLLKDYDEDGFTFFTNYSSNKGQQLTENPFAALVFFWGDLERQIRIEGVIEKISIHESTSYYHSRPKGSQLGAWASPQSSVIPNREFLELNLKKLEEQYKDKEVVPKPDFWGGYRLIPNLIEFWQGRSNRLHDRITYKRQKDESWTIERLAP
>NZ_CP043329.1|WP_149074590.1|1856844_1857345_+|NADH-quinone-oxidoreductase-subunit-C
MTFVEIKELLIQKFGTDSIEAEETQGLQPALVIKKDHIVEVCLALRDNEKTWFDFLSSLSGIDYGVEAQKFGVVYHLTSILKKHQLVLKVYQENDRDEQNLPVFKSVTSVWKTADWHEREAFDLLGIYFEGHPDLRRILLPDDWEGYPLRKDYKTAEQYHNIKIDL
>NZ_CP043329.1|WP_149075882.1|1857385_1858534_+|NADH-quinone-oxidoreductase-subunit-D
MNSVSSEEMVLNLGPQHPSTHGVLRLELITDGEIVKEVIPHLGYLHRCFEKHAEALNYGQIIPFTDRMDYMASMNNNHAFVMGVEKMLGIEDKIPKRVEYIRVLVCELNRIASHLIAIGTYGIDIGAFTPFLWCFRDREHIMNMLEWTSGARMLYNYIWVGGLFYDVPVGFEERCVEFVKYFKPKMKELNELLTENQIFISRTANVGVLPLDVAINYGCSGPMLRGSGLKYDLRREDEYSVYPELDFEIPYAKGEIGTVGDCWNRYKVRIDEIAESLKIIEQCAVKLQHEHKRTPDFDPRALVPKKVVPKQQDFYCRAENPKGEIGFYFIADGKSDKPFRVKSRGPSFNNLSVISEISKGVLIADLVAIIGSIDIVLGEVDR
>NZ_CP043329.1|WP_149074591.1|1858613_1859711_-|trypsin-like-serine-protease
MSSELVLIKRIEAYLYQEMSDEEMMQFEQERAENPALDAKVIAHIDFLKSLKNYGEVQDLKASMEDFHQELNVIALKEELEEKEPAVVLFFRKYKRNLAVAASVAILATLITLISTGQFRKATNSSTYNALKRDMESIKKSQNALIRDINSKSPNKEIAPSQFGGTGFALSSNGYLVTNYHVVQGADSVYIQNNKGESFKVQTIYIDPSYDIAILQIVDPLFESLSPLPYTFKKSSSDLGEDVYTIGYPRDEVVYGKGYLSAQTGFGGDSIAYQVSIPVNPGNSGGPLMDNRGNVIGVISGKQTQVDGAAFAIKSDYLLKAIDNIPQDSLKKKLKINHKNSLASFNRTQQIKKMQDYIFMVKVYN

Crispr_ID: NZ_CP043329_5

• CRISPR_ID: NZ_CP043329_5
• CRISPR_location: 2294030-2294140
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP043329_5

Consensus_repeat	Method
GAGTACTTAAAATGGACTTTCGATTT	CRISPRCasFinder

spacers of NZ_CP043329_5

>5.1|2294056|59|NZ_CP043329|CRISPRCasFinder
TTCCTATCCCAAAAACTAGATTATGTAGATGACAACCTCTCATTGCGCTCGTTTGCAAC

CRISPR arrays and Neighbor proteins around NZ_CP043329_5

CRISPR arrays

The CRISPR arrays of NZ_CP043329_5

>merge|NZ_CP043329|5|2294030-2294140|CRISPRCasFinder
GAGTACTTAAAATGGACTTTCGATTTTTCCTATCCCAAAAACTAGATTATGTAGATGACAACCTCTCATTGCGCTCGTTTGCAACGAGTGCTTAAAATGGACTTTCGATTT

>NZ_CP043329|5|3|2294030-2294140|CRISPRCasFinder
GAGTACTTAAAATGGACTTTCGATTT	TTCCTATCCCAAAAACTAGATTATGTAGATGACAACCTCTCATTGCGCTCGTTTGCAAC
GAGTGCTTAAAATGGACTTTCGATTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149074832.1|2294936_2295908_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|226361
NZ_CP043329.1|WP_149074839.1|2302323_2303100_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293839
NZ_CP043329.1|WP_149074827.1|2288248_2289658_+|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl|CDD|235490
NZ_CP043329.1|WP_149074836.1|2298210_2299728_-|GH3-auxin-responsive-promoter-family-protein	unknown	unknown	gnl|CDD|377019
NZ_CP043329.1|WP_149074829.1|2290608_2292126_+|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|163683
NZ_CP043329.1|WP_149074824.1|2280978_2282724_+|biosynthetic-type-acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|272915
NZ_CP043329.1|WP_149074838.1|2300518_2302219_-|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl|CDD|273193
NZ_CP043329.1|WP_149074835.1|2297569_2298142_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224511
NZ_CP043329.1|WP_039452193.1|2292218_2293277_+|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl|CDD|234832
NZ_CP043329.1|WP_149074825.1|2282743_2283346_+|acetolactate-synthase-small-subunit	unknown	unknown	gnl|CDD|183365
NZ_CP043329.1|WP_149074840.1|2303096_2303507_-|response-regulator	unknown	unknown	gnl|CDD|381108
NZ_CP043329.1|WP_149074828.1|2289806_2290403_+|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|179314
NZ_CP043329.1|WP_149074830.1|2293508_2293916_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074837.1|2299767_2300508_-|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213185
NZ_CP043329.1|WP_149074826.1|2285105_2286617_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|182852
NZ_CP043329.1|WP_149074823.1|2279333_2281013_+|dihydroxy-acid-dehydratase	unknown	unknown	gnl|CDD|234861
NZ_CP043329.1|WP_149074833.1|2296014_2296830_-|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|372635
NZ_CP043329.1|WP_039452214.1|2283487_2284969_+|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235368
NZ_CP043329.1|WP_168199421.1|2296836_2297589_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149074831.1|2294180_2294753_+|transposase	unknown	unknown	gnl|CDD|376616

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149074832.1|2294936_2295908_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	4.08224e-75
NZ_CP043329.1|WP_149074839.1|2302323_2303100_+|MBL-fold-metallo-hydrolase	gnl|CDD|293839	cd16281, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.20173e-34
NZ_CP043329.1|WP_149074827.1|2288248_2289658_+|3-isopropylmalate-dehydratase-large-subunit	gnl|CDD|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP043329.1|WP_149074836.1|2298210_2299728_-|GH3-auxin-responsive-promoter-family-protein	gnl|CDD|377019	pfam03321, GH3, GH3 auxin-responsive promoter.	1.97261e-162
NZ_CP043329.1|WP_149074829.1|2290608_2292126_+|2-isopropylmalate-synthase	gnl|CDD|163683	cd07945, DRE_TIM_CMS, Leptospira interrogans citramalate synthase (CMS) and related proteins, N-terminal catalytic TIM barrel domain. Citramalate synthase (CMS) catalyzes the conversion of pyruvate and acetyl-CoA to (R)-citramalate in the first dedicated step of the citramalate pathway. Citramalate is only found in Leptospira interrogans and a few other microorganisms. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	5.42039e-172
NZ_CP043329.1|WP_149074824.1|2280978_2282724_+|biosynthetic-type-acetolactate-synthase-large-subunit	gnl|CDD|272915	TIGR00118, Probable_acetolactate_synthase_large_subunit, acetolactate synthase, large subunit, biosynthetic type. Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family].	0
NZ_CP043329.1|WP_149074835.1|2297569_2298142_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	5.56376e-33
NZ_CP043329.1|WP_039452193.1|2292218_2293277_+|3-isopropylmalate-dehydrogenase	gnl|CDD|234832	PRK00772, PRK00772, 3-isopropylmalate dehydrogenase; Provisional.	0
NZ_CP043329.1|WP_149074825.1|2282743_2283346_+|acetolactate-synthase-small-subunit	gnl|CDD|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	1.13102e-28
NZ_CP043329.1|WP_149074840.1|2303096_2303507_-|response-regulator	gnl|CDD|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.41514e-16
NZ_CP043329.1|WP_149074828.1|2289806_2290403_+|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	3.86546e-93
NZ_CP043329.1|WP_149074826.1|2285105_2286617_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|182852	PRK10938, PRK10938, putative molybdenum transport ATP-binding protein ModF; Provisional.	4.67587e-93
NZ_CP043329.1|WP_149074837.1|2299767_2300508_-|LPS-export-ABC-transporter-ATP-binding-protein	gnl|CDD|213185	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system. The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.	3.80312e-147
NZ_CP043329.1|WP_149074838.1|2300518_2302219_-|single-stranded-DNA-specific-exonuclease-RecJ	gnl|CDD|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	5.67452e-176
NZ_CP043329.1|WP_149074823.1|2279333_2281013_+|dihydroxy-acid-dehydratase	gnl|CDD|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NZ_CP043329.1|WP_149074833.1|2296014_2296830_-|outer-membrane-beta-barrel-protein	gnl|CDD|372635	pfam13568, OMP_b-brl_2, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	4.62583e-05
NZ_CP043329.1|WP_039452214.1|2283487_2284969_+|ketol-acid-reductoisomerase	gnl|CDD|235368	PRK05225, PRK05225, ketol-acid reductoisomerase; Validated.	0
NZ_CP043329.1|WP_149074831.1|2294180_2294753_+|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.84892e-08

Protein sequences

>NZ_CP043329.1|WP_149074830.1|2293508_2293916_-|hypothetical-protein
MGIHKLTEENQYNLIELILRLHKIDLKLFKSDDDLKALLKFNEVFQIDVSHYDDFHRRICYLRVAKEIYLLKIKSDNYYVDFRQLLKDVRYLNLSSNEDVQELIDEVINKDNLIHYKVLSKSYSYWGEIQKRIIF
>NZ_CP043329.1|WP_039452193.1|2292218_2293277_+|3-isopropylmalate-dehydrogenase
MKLNIALLAGDGIGPEVINQAVKVVNAVATKFNHEINWTSALTGACAIDDCGEPYPDSTHEVCMAADAVLFGAIGHPKYDNDPKATVRPEQGLLKMRQKLGLFANVRPTFTFPSLIDNSPLKRERIEGTDLIILRELTGGIYFGERGRKDNGNTAFDTCTYTRAEIQRLAKLGFEIAMTRSKKLCCVDKANVLESSRLWRETVQDMEKDYPEVTVSYEFVDAVAMRLVQWPNSYDVLITENLFGDILTDEASVISGSMGLMPSASKGLHTSLYEPIHGSYPQAAGKDIANPLATVLSAAMMFEDAFGLHAEAAAIRDVVNKSLAEGVVTEDLSGSNKAYKTSEVGDWLAKNV
>NZ_CP043329.1|WP_149074829.1|2290608_2292126_+|2-isopropylmalate-synthase
MVNRKIEIMDTTLRDGEQTSGVSFSASEKLTIAQLLLEELHVDRVEIASARVSDGEFQAVKAIMDWANQNGYTNRIEVLSFVDNGVSINWMLNAGVKVQNLLTKGSLNHLTHQLKKTAEQHFAEIAAVIALASQNQIETNVYLEDWSNGMRNSKDYVFQFLDFLSQQSVKRVLLPDTLGVLTPSETYDYIDELKSKYPNIHFDFHAHNDYDLSTANVLEAVKAGIDGLHLTVNGMGERAGNAPMASAVAVINDFLPEVKISLKESSIFKVSKLVETFSGIRIPANKPIVGDNVFTQTAGIHADGDNKNNLYFNDLLPERFGRKRTYALGKTSGKANIEKNLQELGLKLNDEDLKKVTQRVIELGDKKETVTKEDLPYIISDVLDSKLYEEKVTVQSYVLTHAKGLRPSATISVSIEGEHFEENAQGDGQFDAFMNALNKVYAKKKRQLPKLVDYAVRIAPGSDSDALCEAIITWETDKKSFKTRGLDSDQTVCAIKATQKMLNII
>NZ_CP043329.1|WP_149074828.1|2289806_2290403_+|3-isopropylmalate-dehydratase-small-subunit
MAYDKFNILKSSAVPLSIENVDTDQIIPARFLKATERVGFGDNLFRDWRYNPDNTPKPDFVLNNPTYSGKILVGGKNFGSGSSREHAAWAVYDYGFRAVVSSFFADIFKNNCLNIGVLPVQVSPEFLDKIFKAIAADPKTALEINLPAQTITLTSTGEQESFDISSYKKENMMNGFDDIDYLQNIKSEIQEFATHLPL
>NZ_CP043329.1|WP_149074827.1|2288248_2289658_+|3-isopropylmalate-dehydratase-large-subunit
MSKTLFDKVWDKHVVRKIEGGPDVLFIDRHLIHEVTSPVAFLGLKTRGIKVLYPERTFATADHNTPTINQHLPVADPLSANQLKALEANSKEYGISHWGLGHQKNGIVHVVGPEYGITQPGATIVCGDSHTSTHGAFGAIAFGIGTSEVEMVLSTQCIMQPKPKKMRITINGTLSRGVTPKDVALFIISKLTTSGATGYFVEYAGEVFEKMSMEGRMTVCNLSIEMGARGGMIAPDETTFNYIQGREFTPKGAAWDKAMEYWKTLKTDADAVFDKELTYSASEIEPMITYGTNPGMGIGISNQIPDAEQVEGGVETYEKSLNYMGFNEGDSMIGKPVDYVFVGSCTNGRIEDFRAFASVVKGKQKAENVTVWLVPGSHIVESQIKEEGILDILTEAGFTLRQPGCSACLAMNDDKIPAGKYAVSTSNRNFEGRQGPGSRTMLASPLVAAAAAVTGKVTDPRELMEELVG
>NZ_CP043329.1|WP_149074826.1|2285105_2286617_+|ATP-binding-cassette-domain-containing-protein
MSQPVVHINNLNLQYPQTLVLEDLNWTILLGENWLLGGNSGNGKTSLAKAIAGLIPAFGNIEINFNDTSKLPAKVLLVESWYQFKNLEGVANFYYQQRYTSQQAKDTLTVKAELAYYAKEHHLNIADVEPILDRLDFTSLQNSQLIELSSGEHKKLQLVKALWLKPQVLIIDQPYTGLDLKSRKNLNLLLDEAASSGVTLILISNDDDLPSSINRFATIANKKLVAVNTKTDLQQFIPLKENKTVPAFLRTSPVYSSQQIAKMENIQISYGEKQVLKNINWEVKAGEKWLLQGHNGSGKSTLLSLINGDHPQSYANTLYLFGHKRGSGESIWDIKQHIGLISPEFHWYFDASATVWESVASGLYDSVGLFRQLPYSKSILVDELVAYFGLTKEKNRLLNTLPLGAQRLVLLARTIIKNPELLILDEPCQGLDKQQTQYFNQLVDELGSNGMTIIYVGHFESQLPNCLEKRIVLENGEVLLIEEIDKENKKHKALNELSLALSI
>NZ_CP043329.1|WP_039452214.1|2283487_2284969_+|ketol-acid-reductoisomerase
MANYFNTLPLREKLNQLGVCEFMDNAEFADGVNALKGKKIVVVGCGAQGLNQGLNLRDSGLDVSYTLRKEAIEGKRDSWKNATENNFKVGTYEELIPSADVVVNLTPDKQHTAVVNAIMPLMKQGSTLLYSHGFNIVEEGMQIRKDITVIMVAPKCPGSEVRAEYVRGFGVPTLIAVHPENDPEGKGLAQAKAYCVGTGGHRAGVLKSSFVAEVKSDLMGEQTILCGLLQTGSILSFDKMTEKGIDAGYASKLVQYGVEVITEALKHGGVSGMMDRLSNVAKVKAFEVSEELKDIMRPLFQKHQDDIMSGEFSRTMMEDWANGDKNLLAWRAETGETAFEKTAAGDVKIGEQEYFDNYLLMVAFVRAGVELAFETMVEAGIKPESAYYESLHETPLIANTIARKKLFEMNRVISDTAEYGCYLFDQACKPLLADFMKKVDTDLVGKNFNEGKDGSVDNRRLVEINEILRSHQVEVVGVKLRKAMTAMKAIKTA
>NZ_CP043329.1|WP_149074825.1|2282743_2283346_+|acetolactate-synthase-small-subunit
MESKLEKKEFNITVYTENQVGLLSRIAIIFSRRKLNIESLNTSPSEVESIHRFNIVINETEEVVRKVARQLEKQVEVLKVYYNTNEDVIWQELALYKVPTEIIAEHVSVERLLREYGARAVVIRKDYTVFETTGHREETDALVVVLQQYGLIEFVRSARVAIIKASDGFHTKLKQFENREPGESASENEYLNNGDKVFTM
>NZ_CP043329.1|WP_149074824.1|2280978_2282724_+|biosynthetic-type-acetolactate-synthase-large-subunit
MQQKDALLMSSEEETAITVEQLKGSEILLNGLIAEGVETIFGYPGGAIMPIYDALYDYQDRLKHILVRHEQGATHAAQGYARTSGKVGVVFATSGPGATNLITGLADAQIDSTPMVCITGQVFAHLLGTDAFQETDVINITTPVTKWNYQVTDASEIAEVLAKAFHIAKTGRPGPVLIDITKNAQLQLTAYNGYQKCEHIRSYRPAPIIRNNYIEQAAALINEAKKPFVLFGQGVLLGNAEQEFKAFVEKTGIPAAWTILGAGAIPTDHPLNVGMLGMHGNYGPNVLTNECDVLIAIGMRFDDRVTGRLDKYAKQAKVIHLDIDPAEIDKNVKAHVPVWGDCKETLPLLTALVKEKKHEEWLEKFRTYTREEIEQCIDAEINPQSGELTMGEVINQLNQLTKGDAIIVTDVGQHQMVACRYAKFNHTRSNITSGGLGTMGFALPAAIGAKFGAPEKTVVAVIGDGGFQMTLQELGTIMQSGIDVKIMILNNQFLGMVRQWQELFHDRRYSFVDITSPDFVALAKSYYIDGQKISERAELKDALKTMLDHKGSYLLEVMVTKENNVFPMVPQGCSVSEIRLK
>NZ_CP043329.1|WP_149074823.1|2279333_2281013_+|dihydroxy-acid-dehydratase
MELNKYSKTITQDETQPASQAMLYGIGLTREDLAKAQVGIASMGYDGNTCNMHLNDLAEIVKKGVWNNNLVGLKFHTIGISDGITNGTDGMRFSLVSRDVIADSIETVCGGHYYDALIALPGCDKNMPGAIIAMGRLNRPSIMVYGGTIHSGNYKGQSLNIVSAFEALGQKIAGNLSEEDYQGIIEHSCPGAGACGGMYTANTMSSAIEALGMSLPYSSSNPALSQEKKDECLEAGKFIRILMEKDIKPRDIMTRKAFHNAMVVIMVMGGSTNAVLHLIAMARSVGIELTMKDFQDISDSVPVIADLKPSGKYMMEDVHDLGGTPAVMKYLLKKGLIHGDCLTVTGKTVAENLVEVKDLDFDEQKIIFPIESPIKATGHLQMLYGNIATQGSVAKISGKEGERFAGPARVFNGESALIEGISSGKVKAGDVVVIRYVGPKGGPGMPEMLKPTSAIYGAGLGSSVALITDGRFSGGTHGFVVGHIVPEAFEGGNIALINDDDIIEIDATKNTINVMLSEEELAARKAKWTQPEPPVKSGVLYKYFKLVKNATEGCVTDEF
>NZ_CP043329.1|WP_149074831.1|2294180_2294753_+|transposase
MSHQYRVKTQDQIHFITFTVVDWVDIFIRPAYKKIIINSLKYAQENKGLELYAWCLMTNHLHLLVSIKEPFQLSDFVRDFKKFTNKEIIKLMDAEHESRRDWMLYRFSYHAKFNNRIKDYKVWQDGYYTIECFNHHILAQKLDYIHNNPVKAEIVALPEEYLYSSAKNYLNEKGLLNVIKVDTSFSDFMK
>NZ_CP043329.1|WP_149074832.1|2294936_2295908_-|ATP-binding-cassette-domain-containing-protein
MTPLITVHNIYKNFTDATHSGVSGINLEINEGEIVSIVGESGSGKTTLLKLIYGYLIPQGGEVLFEGKRVLGPTEKLIPGHDEMKMVTQELTLNLYARVYDNISSLLSNTDLEVKRDLTMQTMEFLRIDHLAYKKIVELSGGEQQRVAIARAVITEPRVLLLDEPFSQVDTILKKQLRDDIERLARFLKITVIMVSHDPSDGLSLSDKLVIVKDGKVVREGKPQEIYYEPQHAYVAQLIGKANILNGLSFLENGKYAVYPQDVFVNQDGMTAKVKSVHFGGLYQEVEYIAEDKTILSYDFDFIPLAKGDEVNIAFKKLMKLDS
>NZ_CP043329.1|WP_149074833.1|2296014_2296830_-|outer-membrane-beta-barrel-protein
MKQLILIACTVFSFAQLAQAQATDSTVVKKEKNAQVEISKEGVNIHIGKTDSTKKDNKGSFPKVSFGLNIEHFDIGLSKYHNGSDFGFPSSYDFLENNNWKTHTVGFDLLQFGVRFNPNFKIALAGGIDWNHIRLERDVTIRPDAAVLTADPSSETNLEKNRFSSRYLRVPLYFEYRSKQDKHKNRFSFVAGPEVGFLIDGKVKQKTDGGEKIKVKDDYNFTQFRYGANVRLGYGGTGLFFKYYFNDVFADNTAPGLEGYKNLSFGLTFGF
>NZ_CP043329.1|WP_168199421.1|2296836_2297589_-|hypothetical-protein
MEPMSDKELDLLFKSKFTDYEVEPSVSSWSKIEEQLSVKPMQRKKVPFLWMAAASVVVVFGLGLLLWNKPQEQIMLKGKPAVEEGDRVIAQNNAVNTIDEVITNTQPAEAKVETVSRVAQEETPNTTEESNSQENYLASIQTENPEAEQEFAATRTEPVKRITVTELMLLEEENTVKTNKIKSTMLSSLSSSKDESSNQQERIRSVGDLVNFVIAKVDKRENKVLKISKTDESDIEITGINLGLFKYKKD
>NZ_CP043329.1|WP_149074835.1|2297569_2298142_-|sigma-70-family-RNA-polymerase-sigma-factor
MNLQHKYAQEEIIQGCQAGERRYQELLYKMMSSKMLGVCMRYAKDQFEAEDMMQTAFVKVFRNINAYRGEGSFEGWIRRIMVNTSIEVYRKNLRSLNVVDIDETHDHQASTAFDMSRLNIADLMRLIRNLSDGYRLVFNMYAIEGYSHKEIAKELGITEGASKSQLSRARAILREQILKMEGNSYGTHVG
>NZ_CP043329.1|WP_149074836.1|2298210_2299728_-|GH3-auxin-responsive-promoter-family-protein
MTIVNSFLNWIMKKRMHQIELFMKYPNEVQEEWLNTLINSAENTEWGKLYDYKSIENERQFKERVPLQSYDTLKPFIEKMLKGEQNILWPSEIKWFAKSSGTTSDRSKFIPVSEEALEECHFKGGKDMLAIYCNNRPDAKMFTGKSLVLGGSHQINQLSPDSFYGDLSAVIIKNLPIWAEMMRTPDMSIALMDNYEEKIEKMARATMDVNVTNIAGVPTWTIVLAKRVLELTGKNNLMEVWPNLELYVHGAVNFEPYQEQFKMLIPNEQMFYLETYNASEGFFGIQDQSEDKDLLLMLDYGIYYEFLPMEHFDEENPKTLSLSEVELNKNYAIIISTNAGLWRYVIGDTVKFTSLDPYRIKITGRTKHFINAFGEEVIIDNAEKALTKACAETNAIIKDYTACPIYFQGNEAGGHEWIIEFEKKPNEFNRFVDILDNTLREVNSDYDAKRFKDMALRRPTVHIAPDNTFYKWLKQKGKLGGQHKVPRLANNRTYVDEILQIIQSS
>NZ_CP043329.1|WP_149074837.1|2299767_2300508_-|LPS-export-ABC-transporter-ATP-binding-protein
MILRAENLIKKYKQRTVVNNVSFHVGQGEIVGLLGPNGAGKTTSFYMIVGLIRPNEGNVFLEDENITQDPMYRRAQKGIGYLAQEASVFRKLTVEDNIKAVLEMTQLSKAEQKDKLEQLIDEFSLHKVRKNRGDLLSGGERRRTEIARALAADPKFILLDEPFAGVDPIAVEEIQTIVARLKHRNIGILITDHNVNETLSITDRAYLLAEGKIMLAGTPQEIADNEMARKFYLGQHFVLKIKNFKV
>NZ_CP043329.1|WP_149074838.1|2300518_2302219_-|single-stranded-DNA-specific-exonuclease-RecJ
MEKRWVEHSIQDLETVNLLSEELNIDEILAQMLVARGIKTFEQAKLFFRPSLDDLHDPFLMNGMEEAVSRIQRAIKNQEHILIYGDYDVDGTTSVALTYSFFKDLYPHLTYYIPDRYVEGYGISTQGIDYAAHHGISLIIALDCGIKSIDKVEYAKEKGIDFIICDHHLPGDEIPDAIAVLDPKRKDCNYPYKELSGCGLGFKLIQAFASRNDIPQEKVLKYLDLVVVSIASDIVPITGENRILAHYGLKKLNSEPCNGLKALIELSGKADDFTITDIVFSIGPRINAAGRIDDAKQAVKLLIASSTQLAEDAGFIINLKNSERKEFDNNITEQALNMILNSPEMEKRKSTVVYHETWHKGVIGIVASRLTEKYYRPTIVLTQSNGHIAGSARSVLGYDLYEALCECSDLLEQFGGHKYAAGLTMKPENLPAFIHKFEEVVSATITDDMLMQVIEAEKCIDLKDITPKFFRILKQFAPFGPQNMAPVFISRNVYSYGYGSIVGNNHLKMSVRQKDSQVFDCIAFGHGDFLEQINRGIPFDICYTIEENVWKDKRSIQLNIKGIKTY
>NZ_CP043329.1|WP_149074839.1|2302323_2303100_+|MBL-fold-metallo-hydrolase
MLEIIALNEGSYSVDSSKKFIPFDPSIHKASERPASLFIHINPFLIKTEKELLILDTGLGYNDEKGNLILHENIKKAGYHPDDVTKVLMSHLHYDHSGGMVWDKQGKLEPSFANAEYIIQQGEWETAYAKQSSSYKTEIFDVIQRSGQVHFIEGNGILTDEISYELTGGHCEYHQVYHIKNDEHEIFFGGDVVPEPEQLQRNFIAKYDYDGKLAKDLRTEYGKKAAINNWICLFYHAKNRAIGTVKEDEQGNIRVDAF
>NZ_CP043329.1|WP_149074840.1|2303096_2303507_-|response-regulator
MIDETLHILIIDDDEINNFIAAKLIDKIPPRARVSTCLNGQEGINYITSRLNNQKDLPDIIFLDINMPIMNGWEFLEEYAAVTHQISKKIVINMLSSSVYNDDISKSKTYPTVNRFISKPLTIEKIQDLYQSLGIS

Crispr_ID: NZ_CP043329_6

• CRISPR_ID: NZ_CP043329_6
• CRISPR_location: 2701265-2701394
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP043329_6

Consensus_repeat	Method
TTATTTTGGAATTACGATTGACGATTTTTGATTTTTCCTT	CRISPRCasFinder

spacers of NZ_CP043329_6

>6.1|2701305|50|NZ_CP043329|CRISPRCasFinder
GCGCTCGTTTCTAAAAAGTGCTAAATATGGTTTTGCGATTCTATCGCAGC

CRISPR arrays and Neighbor proteins around NZ_CP043329_6

CRISPR arrays

The CRISPR arrays of NZ_CP043329_6

>merge|NZ_CP043329|6|2701265-2701394|CRISPRCasFinder
TTATTTTGGAATTACGATTGACGATTTTTGATTTTTCCTTGCGCTCGTTTCTAAAAAGTGCTAAATATGGTTTTGCGATTCTATCGCAGCTTTATTTTGAATTACGATTGACGATTTTTGATTTTTCCTT

>NZ_CP043329|6|4|2701265-2701394|CRISPRCasFinder
TTATTTTGGAATTACGATTGACGATTTTTGATTTTTCCTT	GCGCTCGTTTCTAAAAAGTGCTAAATATGGTTTTGCGATTCTATCGCAGC
TTTATTTTGAATTACGATTGACGATTTTTGATTTTTCCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149075063.1|2689354_2690065_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235990
NZ_CP043329.1|WP_039448830.1|2704262_2705324_-|M20-family-metallo-hydrolase	unknown	unknown	gnl|CDD|349902
NZ_CP043329.1|WP_149075068.1|2696940_2697816_+|DUF115-domain-containing-protein	unknown	unknown	gnl|CDD|376693
NZ_CP043329.1|WP_149075062.1|2687712_2688984_-|hypothetical-protein	unknown	unknown	gnl|CDD|200557
NZ_CP043329.1|WP_149075071.1|2701465_2702797_-|argininosuccinate-lyase	unknown	unknown	gnl|CDD|179143
NZ_CP043329.1|WP_149075069.1|2697815_2699999_+|oligosaccharide-flippase-family-protein	unknown	unknown	gnl|CDD|100040
NZ_CP043329.1|WP_026905346.1|2705330_2706152_-|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl|CDD|237008
NZ_CP043329.1|WP_149075074.1|2708063_2708354_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl|CDD|226194
NZ_CP043329.1|WP_149075073.1|2707091_2708045_-|acetylornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|235304
NZ_CP043329.1|WP_039448842.1|2692399_2692660_+|DUF4834-family-protein	unknown	unknown	gnl|CDD|374375
NZ_CP043329.1|WP_149075070.1|2700005_2701262_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|235596
NZ_CP043329.1|WP_149075067.1|2696140_2696875_-|glycosyltransferase	unknown	unknown	gnl|CDD|133055
NZ_CP043329.1|WP_149075075.1|2708585_2709719_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|227325
NZ_CP043329.1|WP_039448824.1|2709761_2710115_-|four-helix-bundle-protein	unknown	unknown	gnl|CDD|319869
NZ_CP043329.1|WP_149075064.1|2690316_2692347_+|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl|CDD|235395
NZ_CP043329.1|WP_026905351.1|2708350_2708548_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_039448831.1|2702876_2704226_-|Fic-family-protein	unknown	unknown	gnl|CDD|225718
NZ_CP043329.1|WP_149075072.1|2706156_2707011_-|acetylglutamate-kinase	unknown	unknown	gnl|CDD|239771
NZ_CP043329.1|WP_149075066.1|2693584_2696068_+|hypothetical-protein	unknown	unknown	gnl|CDD|226888
NZ_CP043329.1|WP_149075065.1|2692736_2693168_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149075063.1|2689354_2690065_-|SDR-family-oxidoreductase	gnl|CDD|235990	PRK07326, PRK07326, SDR family oxidoreductase.	7.58784e-145
NZ_CP043329.1|WP_039448830.1|2704262_2705324_-|M20-family-metallo-hydrolase	gnl|CDD|349902	cd05651, M20_ArgE_DapE-like, M20 peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases. Peptidase M20 family, uncharacterized protein subfamily with similarity to acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE) subfamily. ArgE/DapE enzymes catalyze analogous reactions and share a common activator, the metal ion (usually Co2+ or Zn2+). ArgE catalyzes a broad range of substrates, including N-acetylornithine, alpha-N-acetylmethionine and alpha-N-formylmethionine, while DapE catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelate (L,L-SDAP) to L,L-diaminopimelate and succinate. Proteins in this subfamily are bacterial, and have been inferred by homology as being related to both ArgE and DapE.	0
NZ_CP043329.1|WP_149075068.1|2696940_2697816_+|DUF115-domain-containing-protein	gnl|CDD|376693	pfam01973, MAF_flag10, Protein of unknown function DUF115. This family of archaebacterial proteins has no known function.	0.0039922
NZ_CP043329.1|WP_149075062.1|2687712_2688984_-|hypothetical-protein	gnl|CDD|200557	cd10931, CE4_u7, Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily. This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.	2.66203e-75
NZ_CP043329.1|WP_149075071.1|2701465_2702797_-|argininosuccinate-lyase	gnl|CDD|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_CP043329.1|WP_039448831.1|2702876_2704226_-|Fic-family-protein	gnl|CDD|225718	COG3177, COG3177, Fic family protein [Function unknown].	3.8721e-23
NZ_CP043329.1|WP_026905346.1|2705330_2706152_-|pyrroline-5-carboxylate-reductase	gnl|CDD|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.17072e-70
NZ_CP043329.1|WP_149075074.1|2708063_2708354_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl|CDD|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	1.73499e-06
NZ_CP043329.1|WP_149075073.1|2707091_2708045_-|acetylornithine-carbamoyltransferase	gnl|CDD|235304	PRK04523, PRK04523, N-acetylornithine carbamoyltransferase; Reviewed.	1.25629e-91
NZ_CP043329.1|WP_149075067.1|2696140_2696875_-|glycosyltransferase	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.48827e-75
NZ_CP043329.1|WP_149075070.1|2700005_2701262_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	1.33029e-67
NZ_CP043329.1|WP_039448842.1|2692399_2692660_+|DUF4834-family-protein	gnl|CDD|374375	pfam16118, DUF4834, Domain of unknown function (DUF4834). This family consists of uncharacterized proteins around 90 residues in length and is mainly found in various Parabacteroides and Bacteroides species. Protein in this family are characterized by a strongly conserved KDEGEYVD motif on the C-terminal and a very divergent N-terminal. The function of this family is unknown.	4.12034e-09
NZ_CP043329.1|WP_149075075.1|2708585_2709719_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|227325	COG4992, ArgD, Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism].	1.01524e-140
NZ_CP043329.1|WP_039448824.1|2709761_2710115_-|four-helix-bundle-protein	gnl|CDD|319869	cd16377, 23S_rRNA_IVP_like, 23S rRNA-intervening sequence protein and similar proteins. A family of functionally uncharacterized bacterial proteins, some of which are encoded by an atypically large intervening sequence present within some 23S rRNA genes. The distantly related bAvd protein, which also forms a homopentamer of four-helix bundles, has been suggested to interact with nucleic acids and a reverse transcriptase.	3.95693e-52
NZ_CP043329.1|WP_149075064.1|2690316_2692347_+|excinuclease-ABC-subunit-UvrB	gnl|CDD|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP043329.1|WP_149075069.1|2697815_2699999_+|oligosaccharide-flippase-family-protein	gnl|CDD|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	3.67546e-53
NZ_CP043329.1|WP_149075072.1|2706156_2707011_-|acetylglutamate-kinase	gnl|CDD|239771	cd04238, AAK_NAGK-like, AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in bacteria and photosynthetic organisms using either the acetylated, noncyclic (NC), or non-acetylated, cyclic (C) route of ornithine biosynthesis. Also included in this CD is a distinct group of uncharacterized (UC) bacterial and archeal NAGKs. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	8.337e-76
NZ_CP043329.1|WP_149075066.1|2693584_2696068_+|hypothetical-protein	gnl|CDD|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0.000104172

Protein sequences

>NZ_CP043329.1|WP_149075070.1|2700005_2701262_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MKVSVLAETLIGSEIIKIAGEVNQMKAKGAQIANLTIGDFDAQLYPIPAELQSNIVDAYADFQTNYPPADGVLTLRESVSDFLKSRMGLDYAAKNEILISGGSRPLIYATYLALIDAGDKVVFPAPSWNNNHYVHLLGAHGISVATQPENNFMPTAAELKPHLKGASLLALCSPLNPTGTMFSEQGLREICELVIAENKSRTAGEKPLYILYDQIYAQLTFGEHQHVDPVTLFPELRDYTVFIDGSSKCFAATGVRVGWGFGPAEIIDKMKAIVGHMGAWAPKAEQVAMAKYLKDTLAVDTYLGDFKTRIQNSLDTLYKGINALKNEGFAVDAIEPMGAIYLTLKIDYLGKSTPEGEVLKSSIDLNFYLIKEANIALVPFSAFGTNDMCWYRASVGACSADEIAAKIPQLKEALAKLK
>NZ_CP043329.1|WP_149075069.1|2697815_2699999_+|oligosaccharide-flippase-family-protein
METLLLNPISLWLRWLFTKAVYLFKNRGKHLKIEYMVELSSCTFGSYNTIYKYTRLRNSTIDSFSYVARNTLVQHAKIGKFCCIGPHVSIGLGAHPSSQYVSSHPLFYSIIGQASGLTLVEKELFQEYQETIIENDVWIGAQVIIKSGVKIGNGAIIASGSVVTKDVEPYSVVGGVPAKFIKYRFAQEQITFLQKFKWWEQNLDWLKEHKDLFLDVDLLMKNLIVNSLDRKESYKTGTIGSQTIKGSIYSYLGIIIGFFSVTVLRSHGLGPEENGILDLILSFTMILAQLGSLGFFNASIRCFPYFRDETKNHNGFMFLLLAIPFVGLLLFTLLFYLGKSVLPVESNFTTLFQDYTPVILALTLGTVLFNALDTFNRTALLDAVTGSTLKEFVQKLTVAIAMGLMLYFTLPFPLFLWIWVLANLIPTVWIFIKLYRKKVFNLKPDFAFLNPEMVKMLSSVSLFAVLTGFTTMIIQYIDKIMINEMINTSLTGIYSITAFFGTVVLMPSRIMYRIGGIIIAEKWKVHDIDGIKSVYKKSCINQLLIAMLIFIGIWANIDNVFEMIPKEYEAGKYVILFISLSGLIEMATGFNGVIIATSKYYKYDTYFFLALIFITIATNYIFIPIWGITGSAMATALATLLFNFFRYLFLVIKFKMQPMGLNNLFILMIGLFTLFIIGYLPKQSFFVWDIILRSGIITLVYVSSIYVLKLAPEMNTIIDKYKTKLLS
>NZ_CP043329.1|WP_149075068.1|2696940_2697816_+|DUF115-domain-containing-protein
MQQLENIYKSFNWFFSNLINTIFSFCKVFLISGFNQKIHKTTPHDSCIILGNGPSLSNSLKEYQDYLAKYSLVCVNLFALTPEYEQLKPAYYVMHDPALWKTELPLPQKVFAAVKEKTNWHITLFFPYRARKSAFVRALNSEHIKVVYYNYTIFKGFNAIAFSLFKQQLAMPQSQNVLVASLFLSINLRYKEVYVIGADHTWHENLIVNDENILCLKNVHFYSEGEQVSYKPFYKGLNTQETFKVSEIFENWTKVFRGYEHIKKYAKYCNTNIYNASHVSFIDAFERKKIS
>NZ_CP043329.1|WP_149075067.1|2696140_2696875_-|glycosyltransferase
MQKEKPLLSVITIVYNDAKHIERTMLSVLNQTYKPIQYIIIDGASTDGTVDVIKKYQDNLFYFNSEPDKGIYDAMNKGLAVATGDYVLFMNSGDEIYALDTVEKVFACADGADIYYGETLRINEKLESLGPRKHLIPEQFSWKSFKYGMNVGHQAIYVKRALAQPYDLQYRLSGDIDWILKIAKKAKHIVNTQMYVAKFLEGGASKQRHRESLKERYLILQKYYGFWPNIFNHFIITMKSILKK
>NZ_CP043329.1|WP_149075066.1|2693584_2696068_+|hypothetical-protein
MNWFKKNGIHLAVIGVFVILCFIYFAPAFQGKVLVQNDVSQAKAMQMEIMKYKEIDGKAPLWTNSMFGGMPSYQIWATYPKNITTYIMTSYRALFPNPVDMVLLYMLGSYLLFNVLLGLYNDKQKSLNAYLAAIGALAFTFSSYNFIIIEAGHGNKALAIGFFAPVLAGILLTLRGRYLLGAALTALFIALEIRVNHIQMTYYLFLALLILVGIEFYHAYKQKLTKDFFKSIGYLTGAVLIAVIINASMLWTTYEYGQLSIRGKSNLTSTNTPANTGLDKEYAYQWSQGVGESITFLIPNAYGGGSASLLDEKSEVVKNLTSKGIDINQSLDFAKQLPGYWGPKPFTSGPWYFGAFVFFLFVLGLFIVKSRLKWWLLSATLLSLFLSFGKNFSLISDLFFDYFPLYNKFRAVESTLVIASLCIPILAILAFAEILKADKDQKAILKALKNTSYILGGIVVVLLAVPTLLFSFKADNHQDFITQLNQVTGDMSFATSIAQSLVEDRISLFKADALRTLIFIAVGAGILWAIISKKINTTLGTLAIGVLIVTDLWAVDKRYLNNENFVAKAVIDQQFKTREVDEFILRDPDPNYRVLDLTIPTFSSANATYFHKTVGGYHAAKLKRFQEVIEKQFTGSMNQDVLDMLNTKYFITPSKDGQNTSMQVNSTACGNAWFVDKVQFVKNNDEEMVAISSFDPKKEAIINDEFKAQLDDKNLGTSFNGKINLTSYHPDHLKYEYSIGKSALAVFSEVWYPKGWKMYIDGEEKPYIRANYLLRAAKLPGGNHTLEWKFEPESYYFGEKISLIGSILLSLILAFAFYKERIQKLKA
>NZ_CP043329.1|WP_149075065.1|2692736_2693168_-|hypothetical-protein
MKKSTILFMLFISTALVFTSCKKDEEQSEKERVTVLLTSGKWYYQSFNTSRCFNEDSYWEFKSDGSVIDTWGFEGNSRNLTYTVSEDGKSITLISTAANSSTNTYNLTITSINASELKFSINYSSGTSDNVVLAKTALDCVPF
>NZ_CP043329.1|WP_039448842.1|2692399_2692660_+|DUF4834-family-protein
MGGLLKFIIITICVLYILRVLARIFLPFLFKKAIHKMQEKMQQQQGGAYQQQTKPEGKITVDYIPPQKKEPKLDNAGDFVDYEEVK
>NZ_CP043329.1|WP_149075064.1|2690316_2692347_+|excinuclease-ABC-subunit-UvrB
MNFKIESYYKPTGDQPTAIKQLVEGVKSGENYQTLLGVTGSGKTFTVANVIEQTQKPTLILSHNKTLAAQLYGEFKQFFPDNAVNYFVSYYDYYQPEAFLPTTNTYIEKDLQINEEIEKLRLRTTSALMSGRRDVIVVSSISCIYGMGNPEDFSNSVFRFGVGTRISRNAFLHRLVEILYSRTTLEFKRGTFRVKGDTVDIYPAYLDLAYRISFFGDDIEEISAIDPASGKTLEKMDQVAVFPANLFVTPRDRFTSVLHQIGEDMESRKKQFEGEGRFLEAKRLEERTNYDMEMMRELGYCSGIENYSRYFDGRTPGMRPFCLLDYFPDDYLMVIDESHVTVPQIRAMYGGDRSRKLSLVEYGFRLPAALDNRPLNFNEFENLAPQTIYVSATPGDYELEKTEGVVIEQVIRPTGLLDPLIEVRPVINQVDDLLDEIDKTIKLGDRILVTTLTKRMAEELAKYMDRLNIKVRYIHSEVKTLERVEILRGLRLGEFDVLIGINLLREGLDLPEVSLVAILDADKEGFLRSERSLIQTIGRAARNDRGRVIMYADKITDSMRITMEETERRREKQIKYNEEHGIVPKTVGKSREAIIEQTSVVDFKGGVQQTYVDNAEVTLAADPIVQYMTKAQLKKSLDNTKKDMLAAAKDMDFLLAAKLRDEMFALEKMMEEKFGK
>NZ_CP043329.1|WP_149075063.1|2689354_2690065_-|SDR-family-oxidoreductase
MQKLQDKVALITGGSKGIGFGIAEALLKQGIKVAITSRSLASAEAAAQKLGHDVLALEADVKDFSSQQEVINKMIAKWGKLDFLIANAGVGHFASIEDLSVSDWNDTIDTNLTGVFYSIKAALPELKKTTGYIFTIASLAGTNFFAGGAAYNASKFGLVGFTQAIMLDLRQYGIKVSTIMPGSVSTHFNEHEPNTEKDAWKIQPEDMGQMVVDLLNMHPRVLPSKVEVRPTKTTNS
>NZ_CP043329.1|WP_149075062.1|2687712_2688984_-|hypothetical-protein
MQLLIYTPKLNSRKQYIFDFLFSQVLGINHQVLDDASTFSNYQGPKISYAPEALADEIHFKSYGLLDELGLKHQDLVSIDYHDVQVFFPVQSSVMPFDVFAASFYLLSRYEEYTNKGRDQHRRFPAKYSISKANSFLHKPVIDIWAYDILNIIHNYYPDLAFQKRQFKFIPTLDIDRPYYFKTEKFTRRILKQFKSLLKGKFTDPFDVYKQVAQWDKYYQTQTQYFILMGNKHQFDVAPDNHNPKFRKLLSKLALGYELGIHPSYESHIHQEEVLKEKQALEDIIQHPIKKSRQHYLKFNLPETFENLLEAGITEDYSMAYADDIGFRAGTCTPFYWYNLKTERSTSLKVFPTVVMDQTLRSYLGLKPQEATEVLNKLIQEVKNVNGTFISLWHNESLSNFGVWKAWKPVYMKLLENASNTNK
>NZ_CP043329.1|WP_149075071.1|2701465_2702797_-|argininosuccinate-lyase
MKLWQKNTSTNNLVETFTVGQDREMDLYLAAFDVLGSLAHTQMLESIGLMTKEDLDKVQHELKNIYREIADGNFTIEDGVEDVHSQVEMLLTQRVGEAGKKIHSGRSRNDQVLVDLKLFFRSQIQEMVLSTKELFDLLTQLAEQHQDKLLPGYTHLQIAMPSSFGLWFGAYAESLIDDLELMLAAFKISNKNPLGSAAGYGSSFPLNRTLTTQLLGFDTLNYNVVYAQMGRGKSERVVAQAMSSIAATLNRMAMDACLFMNQNFGFISFPDELTTGSSIMPHKKNPDVWELIRGRTNQLQALPNQIMMLTTNLPSGYHRDMQLLKETLFPAFNSLMSCLDMAKLMLKNIKIKDNILADDKYAYLFSVEVVNNLVLAGMPFREAYKKVGLDIEAGNFETDRKVNHTHEGSIGNLNLPEVKAMMQNLQAQFKFDKIEMAIDKLVK
>NZ_CP043329.1|WP_039448831.1|2702876_2704226_-|Fic-family-protein
MSRTIEIIDQLWTRLEALKPIKPEYKTKLDKKFRLEFNFNSNHLEGNTLTYGETELLLIFDDTKGNHTLREYEEMKAHDVAYLLVEEWAQDKESPLIEQKIKNLNEIILVRPFWKEAITPDGQNTRRLINIGNYKNHPNSVRLANGEIFHYTSPTDTPFEMQDLIKWYAEGEDNLHPVKLAAMLHYKFVRIHPFDDGNGRVSRLLMNYVLLKHNYPPIIIKSADKQNYLRALHLADVGDYEPFIEYISQQVKWSLEISIKAAKGETIDEQGDLEKKISVLKKKLKQDKEVKLKFDNSVLEKLVKKHIFPLAYEWEKGLKKFDQFFFSREVALNTEFGRVSGMEINEKLTNNFLNKLLLLINNNQKIIRIRFSSSYRKLKSVKDSGSFNGGFIEIQFHQNAYEISYSGSKTTISKLYDEELTKEEMESITNSIGNWFYTQIENAIELYNK
>NZ_CP043329.1|WP_039448830.1|2704262_2705324_-|M20-family-metallo-hydrolase
MDLDILFQDALALLQRLIAIPSLSKEEAKTADEIAVFLQQRGINIHRKGNNIWAYNQHFDAKKPTILLNSHHDTVKPNQGYTRDPFLPEIIDGKLYGLGSNDAGGALVSLIATFLYFYPEENLKYNILIAATAEEEISGKEGLERIVPDLGKLEFAIVGEPTEMHLAVAEKGLLVLDCVTKGKSGHAARNEGENAIYNALKDIAWFRDYQFTKVSPTLGPIKTTVTIINAGSQHNVVPDECKFTVDVRVTDAYTNEEVLKIIRQFVDCEVIPRSTRLKPSSIPIDHPIVQAGMALGRKTYGSPTTSDQALLNIPSLKCGPGDSARSHTADEFIYVDEIEEGIKLYVKMISEII
>NZ_CP043329.1|WP_026905346.1|2705330_2706152_-|pyrroline-5-carboxylate-reductase
MDFKKSNQIAILGSGNIGLSLAKGLAQSGLYPASSITLTRRNIEALDEYKFQGFQVSADNVSASAQADIIVLAVLPQQLNQVLDQIAGQIDVSKHLIISVISGVSCEDIRNRLKKDVQVVRVMPNTAIAIKQSMTCISVGNASQENIELVKNIFNTVGICVVINEELMTSATALCACGIAFFLRSIRAASQGGVEVGFHAGEALKMAAQTAKGAADLLLQLASHPEHEIDKVTSPKGCTIAGLNEMEHNGFSSAMIKGIKLSAQKAGELYDKD
>NZ_CP043329.1|WP_149075072.1|2706156_2707011_-|acetylglutamate-kinase
MGKNNPQDKLDHGSLSFGEGRGEALYIIKIGGNVIDNPIQLAQFLKDFAGLSGAKILIHGGGKIATQTAAKLGVQTQMVNGRRITDAAMLDVVTMVYGGLVNKNIVAQLQANQVNAIGMTGADANAIKAVKRPVKDVDFGFVGDLLPDAVNANIIKTLLEAGLVPVFNALTHDGNGQLFNTNADTIASALALGLSSLYETKLIYCFEKNGVMRDINDDNSVIQEINPSYFEELKADGIIADGMLPKLQNAFDAIQNGVKEVYIGHAAKLAALQKESIFGTRLTK
>NZ_CP043329.1|WP_149075073.1|2707091_2708045_-|acetylornithine-carbamoyltransferase
MKLFSSVKDVSDVNQLVSEAIQLKANPFADEHLGKHKTLGLIFLNPSLRTRLSTQKAAMNLGMQVMVMNMDKEGWALETQDGIIMNGTTVEHIREAAGVMGEYCDIIGIRSFPGLKDRNEDYSELIFNKFVQFCGVPVVSLESATRHPLQSLADLITIEELKTTAKPRVVLTWAPHVKPLPQAVANSFAEWMNKADYDFVITHPAGYDLAPEFVGNAIVTNNQDEALAGADFVYVKNWSSYQDYGKILSDGEGWMMTNEKLKLTNNAGVMHCLPVRRGLELSHEILDGPNSLVLNQANNRVWAAQAVLKMCLTQTLS
>NZ_CP043329.1|WP_149075074.1|2708063_2708354_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKFEIRWSDEAEVTFDAIYQFVSIQWNIKQAEKLRVQTLKVLEQIAVNPYLFKESEIKNVRKAFISKHTSLFYETSQQTILLVFFWDNRQNPMINI
>NZ_CP043329.1|WP_026905351.1|2708350_2708548_-|hypothetical-protein
MTVTYLVDEKGNKTAVQLSMEDYLSLLESANLLPDHVKEGIKRGQEQGKAGLTKSTEEVMRKYNV
>NZ_CP043329.1|WP_149075075.1|2708585_2709719_-|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme
MKLFDVYPINNIEIVKGQGSLVWDDKGQEYLDLYGGHAVISIGHTHPHYVERLTQQLGKLGFYSNSIKIPLQEELADKLGKISGREDYQLFLCNSGAEANENALKLASFANGRKKIVAFTKAFHGRTSLAVSATDNPKIIAPVNQTENVVFLPHNDVDALKTLFAEQGNEICAVIIEGIQGVGGIQVASDEFLQSIRSLCTQYGAYFIADSVQCGYGRSGKFYASDFAGVDADIYTMAKGMGNGFPIGGISISPALKPWHGMLGTTFGGNHLACAAALAVLEVMEQEHLMDNAAKIGGYLIQELQKLNHIKEVRGKGLMIGIDLPEELNQVKKNLLFNHHIFTGEAKPNVIRLLPALNLTREHADRFLEALSKELKA
>NZ_CP043329.1|WP_039448824.1|2709761_2710115_-|four-helix-bundle-protein
MQNYKDLRVWVKSHELTLKIYSVTKNFPKEEIYSVTSQIRRASSSIPANIAEGCGKNTKNDFGKYLNIALGSANETEYFLLLAKDLGYLPIEDYLILEKNINEVKAMLILLIQKVRA

Crispr_ID: NZ_CP043329_7

• CRISPR_ID: NZ_CP043329_7
• CRISPR_location: 3460927-3461018
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP043329_7

Consensus_repeat	Method
AAAGTAAAAAGATGCCTAAAAAGCGAT	CRISPRCasFinder

spacers of NZ_CP043329_7

>7.1|3460954|38|NZ_CP043329|CRISPRCasFinder
GTTTAGGGACTGCCTTTTAAGTAGAAAGTACAGAGTAC

CRISPR arrays and Neighbor proteins around NZ_CP043329_7

CRISPR arrays

The CRISPR arrays of NZ_CP043329_7

>merge|NZ_CP043329|7|3460927-3461018|CRISPRCasFinder
AAAGTAAAAAGATGCCTAAAAAGCGATGTTTAGGGACTGCCTTTTAAGTAGAAAGTACAGAGTACAAAGTATAAAGATGCCTAAAAAGCGAT

>NZ_CP043329|7|5|3460927-3461018|CRISPRCasFinder
AAAGTAAAAAGATGCCTAAAAAGCGAT	GTTTAGGGACTGCCTTTTAAGTAGAAAGTACAGAGTAC
AAAGTATAAAGATGCCTAAAAAGCGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043329.1|WP_149075558.1|3456453_3457869_+|hypothetical-protein	unknown	unknown	gnl|CDD|236766
NZ_CP043329.1|WP_149075559.1|3458454_3458730_+|co-chaperone-GroES	unknown	unknown	gnl|CDD|178988
NZ_CP043329.1|WP_149075562.1|3463491_3464514_-|hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240654
NZ_CP043329.1|WP_039454431.1|3457876_3458218_+|preprotein-translocase-subunit-SecG	unknown	unknown	gnl|CDD|235881
NZ_CP043329.1|WP_149075564.1|3465378_3466029_-|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl|CDD|225002
NZ_CP043329.1|WP_149075561.1|3462013_3463507_-|hypothetical-protein	unknown	unknown	gnl|CDD|212659
NZ_CP043329.1|WP_149075554.1|3451071_3452490_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149075555.1|3452477_3452867_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP043329.1|WP_149075556.1|3453008_3454544_+|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl|CDD|237676
NZ_CP043329.1|WP_149075557.1|3454669_3455899_+|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NZ_CP043329.1|WP_149075563.1|3464681_3465389_-|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl|CDD|319743
NZ_CP043329.1|WP_149075569.1|3474375_3477690_+|preprotein-translocase-subunit-SecA	unknown	unknown	gnl|CDD|237256
NZ_CP043329.1|WP_039454874.1|3471520_3471907_+|RidA-family-protein	unknown	unknown	gnl|CDD|100011
NZ_CP043329.1|WP_039454430.1|3455903_3456416_+|LptE-family-protein	unknown	unknown	gnl|CDD|377341
NZ_CP043329.1|WP_149075567.1|3469425_3470196_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|119339
NZ_CP043329.1|WP_149075566.1|3466716_3469422_+|TonB-dependent-receptor-plug-domain-containing-protein	unknown	unknown	gnl|CDD|274948
NZ_CP043329.1|WP_149075560.1|3458894_3460532_+|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NZ_CP043329.1|WP_149075565.1|3466104_3466641_+|dCTP-deaminase	unknown	unknown	gnl|CDD|234753
NZ_CP043329.1|WP_149075553.1|3449765_3451070_-|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NZ_CP043329.1|WP_149075568.1|3470473_3471349_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187627

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP043329.1|WP_149075558.1|3456453_3457869_+|hypothetical-protein	gnl|CDD|236766	PRK10811, rne, ribonuclease E; Reviewed.	0.000435457
NZ_CP043329.1|WP_149075559.1|3458454_3458730_+|co-chaperone-GroES	gnl|CDD|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	1.90348e-47
NZ_CP043329.1|WP_149075567.1|3469425_3470196_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	1.12115e-49
NZ_CP043329.1|WP_039454431.1|3457876_3458218_+|preprotein-translocase-subunit-SecG	gnl|CDD|235881	PRK06870, secG, preprotein translocase subunit SecG; Reviewed.	1.93673e-13
NZ_CP043329.1|WP_149075564.1|3465378_3466029_-|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	3.46057e-15
NZ_CP043329.1|WP_149075561.1|3462013_3463507_-|hypothetical-protein	gnl|CDD|212659	cd07770, FGGY_GntK, Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases. This subfamily is composed of a group of gluconate kinases (GntK, also known as gluconokinase; EC 2.7.1.12) encoded by the gntK gene, which catalyzes the ATP-dependent phosphorylation of D-gluconate and produce 6-phospho-D-gluconate and ADP. The presence of Mg2+ might be required for catalytic activity. The prototypical member of this subfamily is GntK from Lactobacillus acidophilus. Unlike Escherichia coli GntK, which belongs to the superfamily of P-loop containing nucleoside triphosphate hydrolases, members in this subfamily are homologous to glycerol kinase, xylulose kinase, and rhamnulokinase from Escherichia coli. They have been classified as members of the FGGY family of carbohydrate kinases, which contain two large domains separated by a deep cleft that forms the active site. This model spans both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. Some uncharacterized homologous sequences are also included in this subfamily. The Lactobacillus gnt operon contains a single gntK gene. The gnt operons of some bacteria, such as Corynebacterium glutamicum, have two gntK genes. For example, the C. glutamicum gnt operon has both a gluconate kinase gntV gene (also known as gntK) and a second hypothetical gntK gene (also known as gntK2). Both gluconate kinases encoded by these genes belong to this family, however the protein encoded by C. glutamicum gntV is not included in this model as it is truncated in the C-terminal domain.	6.37134e-110
NZ_CP043329.1|WP_149075569.1|3474375_3477690_+|preprotein-translocase-subunit-SecA	gnl|CDD|237256	PRK12901, secA, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP043329.1|WP_149075562.1|3463491_3464514_-|hydroxyacid-dehydrogenase	gnl|CDD|240654	cd12177, 2-Hacid_dh_12, Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.51912e-132
NZ_CP043329.1|WP_149075556.1|3453008_3454544_+|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl|CDD|237676	PRK14329, PRK14329, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NZ_CP043329.1|WP_149075557.1|3454669_3455899_+|sigma-54-interacting-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	4.89388e-115
NZ_CP043329.1|WP_149075563.1|3464681_3465389_-|lipoyl(octanoyl)-transferase-LipB	gnl|CDD|319743	cd16444, LipB, lipoyl/octanoyl transferase. Lipoate-protein ligase B is a octanoyl-[acyl carrier protein]-protein acyltransferase the catalyzes the first step of lipoic acid synthesis. It transfers endogenous octanoic acid attached via a thioester bond to acyl carrier protein (ACP) onto lipoyl domains, which is later converted by lipoate synthase LipA into lipoylated derivatives.	2.96524e-103
NZ_CP043329.1|WP_039454874.1|3471520_3471907_+|RidA-family-protein	gnl|CDD|100011	cd06154, YjgF_YER057c_UK114_like_6, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	4.41038e-56
NZ_CP043329.1|WP_039454430.1|3455903_3456416_+|LptE-family-protein	gnl|CDD|377341	pfam04390, LptE, Lipopolysaccharide-assembly. LptE (formerly known as RplB) is involved in lipopolysaccharide-assembly on the outer membrane of Gram-negative organisms. The lipopolysaccharide component of the outer bacterial membrane is transported from its source of origin to the outer membrane by a set of proteins constituting a transport machinery that is made up of LptA, LptB, LptC, LptD, LptE. LptD appears to be anchored in the outer membrane, and LptE forms a complex with it. This part of the machinery complex is involved in the assembly of lipopolysaccharide in the outer leaflet of the outer membrane.	4.08057e-07
NZ_CP043329.1|WP_149075566.1|3466716_3469422_+|TonB-dependent-receptor-plug-domain-containing-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	1.16775e-16
NZ_CP043329.1|WP_149075560.1|3458894_3460532_+|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP043329.1|WP_149075565.1|3466104_3466641_+|dCTP-deaminase	gnl|CDD|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	1.64171e-63
NZ_CP043329.1|WP_149075553.1|3449765_3451070_-|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.39678e-62
NZ_CP043329.1|WP_149075568.1|3470473_3471349_+|SDR-family-oxidoreductase	gnl|CDD|187627	cd05369, TER_DECR_SDR_a, Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR. TTER is a peroxisomal protein with a proposed role in fatty acid elongation. Fatty acid synthesis is known to occur in the both endoplasmic reticulum and mitochondria; peroxisomal TER has been proposed as an additional fatty acid elongation system, it reduces the double bond at C-2 as the last step of elongation. This system resembles the mitochondrial system in that acetyl-CoA is used as a carbon donor. TER may also function in phytol metabolism, reducting phytenoyl-CoA to phytanoyl-CoA in peroxisomes. DECR processes double bonds in fatty acids to increase their utility in fatty acid metabolism; it reduces 2,4-dienoyl-CoA to an enoyl-CoA. DECR is active in mitochondria and peroxisomes. This subgroup has the Gly-rich NAD-binding motif of the classical SDR family, but does not display strong identity to the canonical active site tetrad, and lacks the characteristic Tyr at the usual position. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.50154e-124

Protein sequences

>NZ_CP043329.1|WP_149075560.1|3458894_3460532_+|chaperonin-GroEL
MAKQVKYNVEARDALKRGVDILANAVKVTLGPKGRNVIIDKKFGSPAITKDGVTVAKEIELKDALENMGAQMVKEVASKTADIAGDGTTTATVLAQAIVTAGIKNVAAGANPMDLKRGIDKAVTAVVANLKSQSQTVGEDNNKIKQVASISANNDDVIGSLIAEAMAKVGKDGVITVEEAKGTETEVKTVEGMQFDRGYLSPYFVTNADKMEVELDNPYILIYDKKISNMKELLPVLEKQVQTGKPLLIIAEDLDGEALATLVVNKIRGSLKVAAVKAPGFGDRRKAMLEDIAILTGGTVISEERGYKLENADLSYLGQAEKITVDKDNTTIINGVGNSEDIKARVNQIKAQIETTTSDYDKEKLQERLAKLAGGVAVLYVGAATEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVAFIRAVESLEGLKGANEDETTGIKIIKRAIEEPLRQICANAGIEGSIVVHNVKQGKADYGYNARTDVYENLIGAGVIDPTKVSRVALENAASIAAMLLTTECVLADEAEEGSSSPAMPPMGGGMGGMM
>NZ_CP043329.1|WP_149075559.1|3458454_3458730_+|co-chaperone-GroES
MALNIKPIADRVVVEAAPAEEKTASGIYIPDTAKEKPQSGTVVAVGNGKVDEPMTVKVGDQVLYGKYSGTEITYEGKEYLIMRESDIYAVL
>NZ_CP043329.1|WP_039454431.1|3457876_3458218_+|preprotein-translocase-subunit-SecG
MTTFLIILAIVICVLLVLIILVQNPKGGGLSSGFSSSNNIMGVQRTGDFLEKGSWGLAIALMVIALLINVSSPSATTGSGPARDSKIQEQIDKTAAPSALPSLPQGKPADTAK
>NZ_CP043329.1|WP_149075558.1|3456453_3457869_+|hypothetical-protein
MEQLEYKHIKELKFSDYLFDLNQLDEGKLADLEILINKYPYCQTLYLLAAKTAQNTPNFTQKLAQAAAMLPDRTVLYHVIHHPDKLNKDYTVAASQEKEIQPEALVSIIEEDVTLPHALVDVPSETESETALEADSFNHDDEVYEEIADVVVEHISPADEEVKDEHDLNFDTSTPSEFIIEEETEEVVESAQEEAPNAIAEDVIESKEETATTEEVNLEPVFVEIETPDQNTLPFESIIRTGEVTVTTEQVPENDITEEEQPIVETVAAQEPYIENIAQEIEEPEHSTKSEQIKALQISQQKNYISKYDDERLPYTFLWWLAKTRKEYENIQPYASFKLDTSKEIAVKEDVLSHQIAENIFHLRTVDDLTHQQTQTVPFDFRRKEYQIIERFIKEEPQIKPPPANKIDTENKAKRSSEDSHELVSETLAKVYVEQMLYHKALEVYKKLSLKYPEKSTYFASQIKYLELKVN
>NZ_CP043329.1|WP_039454430.1|3455903_3456416_+|LptE-family-protein
MRKRAYILLCAMLMLLNACGIYSFTGGSISAGMKTVSVALFENNAPLVVPILSQSFTEALKDRIRTQTSLSFLRTNGDADFQGRITDYNIQPVAIQGDQQVSAGLNRLTITVQVKYTNTIEPDKSFEQSFTRFRDFSTQGSAFASQEQALIKDINAQLTEDIYNRAFANW
>NZ_CP043329.1|WP_149075557.1|3454669_3455899_+|sigma-54-interacting-transcriptional-regulator
MDIQEIKQRFGIIGASPLLHRAIDIARQVAPTDITVLITGESGSGKEVFSHIIHQLSARKHGPFIAVNCGAIPEGTIDSELFGHEKGSFTGAHEARKGYFEVVNGGTIFLDEVGELPLGTQARLLRVLESGEYIRVGSSKVQKTDVRVVAATNVEMYEAVKAGKFREDLYYRLNTVPLKIPPLRDRREDIHLLFRKFVADFSDKYRSPNVTLDEGAVQVLTNFNWPGNVRQLKNIAEQIAVLEKNRHITAQTLLSYIPQDQQSSLPMRLDNGKKEDFSERDILYKVLFDMKKDMVELKKLVADIIQSGDNVSSYAASHPQILNSLYQDLDVQHVEPQLTIQQPVVNRQDDFHITQDAEEIEESLSLIDKEADMIKKALKKHKGKRKSAAEELGISERTLYRKIKELNLN
>NZ_CP043329.1|WP_149075556.1|3453008_3454544_+|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MLELNIPSKEHDEARQGEALVIEATKNNNGRKLYIESYGCAMNFSDSEIVASILADDGFVTTADFTEADIVFINTCSIRENAEVRVRNRLKQFSASKAKNPGMIVGVLGCMAERLKAKFLEEEKLVDVVVGPDAYRDLPNLINKVDDGNKAVNVLLSREETYADINPVRLNSNGISAFISIMRGCDNMCSFCVVPFTRGRERSRDAHSVVKEAQDLYAAGYREVTLLGQNVDSYKWKKPHPQSLSEGEVSAGDSLEALDNKVIIQEEPLDRSSLSFGEGGGEVVNFAQLLEMVALVSPDLRVRFSTSHPKDITDEVLHTIAKYDNICNYIHLPVQSGNSRVLEIMNRTYDRQWYMERVEAIRRIIPECSISTDIITGFCSETEEEHQDTLSMMDFVKYEFAYMFSYSERPGTPAAKKFKDDIPEEVKQRRLEEVIAKQQINSHYRAQRRIGKVEKVLIEGFSKKSKNDYCGRSDQNFMVIFPVGDAYKPGDYVNVLVEKTTTATLIGKVVE
>NZ_CP043329.1|WP_149075555.1|3452477_3452867_-|hypothetical-protein
MDTGPKPQKFLILKWLLGVFLVVILLLGVGAYYLNKQWKPLLTDALQKAVTDVSDSLYKVKFSDIRINVLTGSAYLDSIHIYPDTSVYNKLIAQKKAPENLFELKISNLGLKMSIHLKYILIENWIWMP
>NZ_CP043329.1|WP_149075554.1|3451071_3452490_-|hypothetical-protein
MDAITITRPELNIIYTRLKYPKKRLEDNRTTYQKIKHLLKSARVGSIFLNNIKFKYIDKSLSLNKPDITNLDNLNIRLNDILIDSAAQYDSTRIFTSKDIIAELKDYSYSTADSLYYIRLAKMQFSTLKKEFLVTQFRLIPRYSEMDFSNLFVKQHERYKISFDTISLKNINYPSLIDERLVSAQKVLLKNGDVSVFLNRGKAPKGIDKGKNFPHLALQRVNWSIHTDSVELNNTKIAYAEYNPKTGAKGTITFHQLRGYLLNVTNTEAFLAKNHFADAHLQTKLLGRGDLNIHIKFDLTDKLGAFSYKGSLGKMPIETINPITRPLAMVMIRSGTINSLDFSAKGNIRSASGFVKINYHDLSVTLMKKDEDNNLKKMGLISLVANALLLKQSNPSKNEALRVSYPTYSRPADGSFFNLMWKVIFMGLKESVGISKEQEEKITEKASKLKEAKIRREKRKAERQQRRRDKQD
>NZ_CP043329.1|WP_149075553.1|3449765_3451070_-|serine-hydrolase
MFKSIKYFSFIAALWLTSACSEQITDKLVASQNLKKLQIEGTNLERIDSLIGSALINNWTAGATALVAKNGEVIYDKGFGFKDRETKSLMRPTDIFRIASMSKPIISVATMILVEQGKLKLDDPVSKYIPEFKNPQVLASFNATDTTYTTVPANKEITIKHLLTHTSGIGYGFADSTLKKIYDKHDIPDLATVKNITIEQSMKKLGTLPLGVQPDAKFYYGLSTDVLGYVIEVASGKKLDFFLKEYIFSPIGMNSTYFFLPPESTYRLAAMYSETPEGRLIKTYPISGKFNINYPIRGAKTYLSGGSGLCSTVEDYALFLQMILNKGTYGGKRILKAETIELMSQNHIGDLQVGKNKFGLGFEIATEQGLANGAKVGKLSWSGAFNTMFWIDPQRNAIAVLMTQVYPAIHKREFYNKFETLVNDALDRGLKEKD
>NZ_CP043329.1|WP_149075561.1|3462013_3463507_-|hypothetical-protein
MVLSLAIDLGTTNLKVGLVNESGEIISIRSVAVPVKSNQKGEAEHDPEELKKLILGLCKELLVGDTKNQVAYIVSSTYQFGLMLLDAHKKPLTGITLLSDIRSQKTFDAFLESYSAFDIYAQTGCPLISPYVLARLFYFSTQEKDLFKKAQYFSDSKSFLFNWLTGEFTTDMSTAAASQAYNITNGTWDDTLLGHIGLEGKQFPEIKDGTSYLSSLQEDIRTELGLKQGVKVLLGVYDGAALAIGSGALQKGVGIMNVGTSAMLRVAGQIPAFDQDDNKRIQPYALNKQLFLNGGALNNAALPINWLRNSLFDVDLHDEAMLNLGTTAPLICLPYLTSERDSKTGPYASGVFFGLRQYHSKTDMARSVLEGVAYSMRYIFDALKENQLLITELRMGGGGTNIKPWVQIFANIMGLPIHIPSGDELGIVGSAMLAFAAEDKDKNINTIGSHGLGNNMTIYPDAAAVEVHHQRYQFFKKLRETLGPLYKEHAALANHPS
>NZ_CP043329.1|WP_149075562.1|3463491_3464514_-|hydroxyacid-dehydrogenase
MRRPLISILNSSTFGKHFADHMSTLEAFADIKHITVPADIDGDALAEYLKDADGIIASVTPKIPRATLEKCKNLVLLVRHGIGCDNVDLEAATELGIMVSRVKGIIEKEAVAEYAVSLLMAGSRKLVSGSRAVRNSDWSKRAGMIGMEIKGKTIGIIGLGNIGSRSSEILAKGFGANVVASDPYIAKERFAQFGAKEVSLDELIKTSSAILFHCPLTDETKRMLGKAQFDSMQKDAVLVNTCRGELVDEDALYAALQNGPLGVYATDVVEGEPIDGNHRLAKLENTIITPHLGGYSWESLHGMGQTCVDDAVSVFQNNGVAGELANPEVLQTKRRVWSSH
>NZ_CP043329.1|WP_149075563.1|3464681_3465389_-|lipoyl(octanoyl)-transferase-LipB
MKNNKVFFQDWGLVPYQQAWDKQEAVFAETVAIKTVNRNHPETAQQTPNYLIFVEHPHVYTLGKSGKAENLLLNEQALIEKEASFHKINRGGDITYHGPGQLVGYPILDLDNFFTDIHLYLRTLEEAVILTLKDYGITAGRYEGYTGVWLDADNEKARKICAMGVRCSRWVTMHGFAFNVNANLDYFKNIVPCGIDDKDVTSMQRELGKAIDMDEVKAKLKQHIANLFEMDLSNT
>NZ_CP043329.1|WP_149075564.1|3465378_3466029_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MPLTFLEEIHPNTYIGLWKIEEEPAVLEKQLQLKDHEKEVLKGLNTQKRNLHWLATRVLLRKMLNTEEYIDCQPDENGKPVLLNMPHHISLSHSYDYAAVIISKDKRVGIDIEIIKDKITRVQQKFMSPQELSFMDEQYAIEHLYVCWCAKEALYKLNGKKETSFKDDIHLEEFPYQTKGVLKGSIHKEPLVKNYKIAYRKFEDYMLGYVYEEDEE
>NZ_CP043329.1|WP_149075565.1|3466104_3466641_+|dCTP-deaminase
MILSDQRILEEIEKGTIIIEPFKKECLGTNSYDVHLGKYLACYTDRILDAKKHNQIEHFEIPKEGFVLQPNTLYLGVTLEYTETHQHVPFLEGKSSTGRLGIDIHATAGKGDVGFCNTWTLEISVAQPVRIYAGMPIGQLIYFVVEGDIQTLYNTKGNAKYNNKTTRPVESMMWKNNF
>NZ_CP043329.1|WP_149075566.1|3466716_3469422_+|TonB-dependent-receptor-plug-domain-containing-protein
MRKFHFLFLLFIASIFVAFVAQDDKLKQVMANFNKFHTSHTQEKIYLHTDKPYYATGDQIWFKAYVVDAQTMRPSALSKIMYVDLINQKNQVKKTLRLPLTAGFGWGNIELADSLKEGNYRLRAYTNWMRNFDEAFFYNQTFKVGDIRSSQVITQTNYEFSKADGKELVVAKINFKNVDGFPYANREVEYTVELDGRQTERGKANTDDKGNVIINITNNKPEIIKSGMLSTALKISEGTLVNKFIPIISTSNQIDVQFFPEGGDMITQVRSRVAFKAVGSDGLGKAIKGYVQDNNGKRIANITSRYAGMGYFSIYPEANLTYEAVVTFDDGSEKKFPLPAVKPEGIVLSAIDRGQDSLLLRVQTNDAYSSTHLGKNFTVVAQSSGNIIYSAVAKLSKNGFAAYIPKVQFPTGIIQLTLFNDQMQPLSERLIFHAHTKDFLNIEVKPDKEVYTKRGKVNIAVTAKTNENNPMVSSLSMSVIDEGKVPVKPEEEHTILSELLLKSDLKGHIENPNYYFHEVDDKKKGDLDVLLMTQGWRRFNWQNLITNTLPSLAFKPEKTLSIAGTVTNNKKPVVNGNITVFSSSGGTFIIQAKTDEAGKFEIDSLLFPDSTKFVVQARTIKDRKFVEIVMDEFGKHPVQTPFAKSELSANINSSMAAYIKNSKSQYEELLKNGLITRSIMLDEISVIEKREKLQNSSNLNGGGNADRVITAEELQNAPNLEFALQGKVAGMMIQNGEIFFMRNMGGPPAQIILDGIFVEADFLNTIAPQDVESIEIMKPGALTSIYGSRGGSGVIVINTKRGGGNYTSTNTYTPGLIAYQPIGFTAMKQFYVPAYDKAETKKDMADFRSTIYWNPTVITDTTGNAKVNYFNADGTGTYRVVVEGLDIYGRLGRKVIRYKVN
>NZ_CP043329.1|WP_149075567.1|3469425_3470196_+|enoyl-CoA-hydratase/isomerase-family-protein
MNTLSVTIREKVAIIALNRGKSNAMNAELVKELKSLIKNIEQDDQILGAILTGKEGFFTAGLDLIELYAYDENQIKSFWVDFLDLVKTLTLFKKPLVAAISGHSPAGGCVMALCCDYRVMAEGKYIIGLNEVPVGIIVPDSIFHLYAFWLGQAKAYQSLLEGKLFSVDEAKQIGLLDATSDISSLMSHAQKKIQSYLQYDATTWQQSKLNLRKELIAKVSADQTSTLDIMLKQWWAPSTRSILKTIIENLKGGSEK
>NZ_CP043329.1|WP_149075568.1|3470473_3471349_+|SDR-family-oxidoreductase
MYNQPMLRDNALEGKTFVVTGGGTGLGKAMSTYLLELGAQVVITSRKLEVLQKTAQELEAKTGGKVLPLACDVRNAEQVDEVLAASLAAFGKVDGLLNNAAGNFISPTERLSANAFSTIIDIVLKGTVNCTLAFGKHWIKEKQAASILNIVTTYAFTGSGYVVPSACAKGGVLAMTKSLAAEWGRYQIRCNAIAPGPFPTKGAWERLLPGDMAKKFDFKNRVPLKRVGEHQELANLAAYLLSDFSNYINGEIITIDGGEWLQGAGQFNGLEMISPEMWDALEAMIRNTKGS
>NZ_CP043329.1|WP_039454874.1|3471520_3471907_+|RidA-family-protein
MTNRQNFTTGSPWEDIIGYCRAVKVGNTIEIAGTTMAKDADGNAITTLYGQTKAILEKLKSVLEDADASLENVVRTRMFLTDISQWEEAAKAHGEYFKDIKPVTTMVEVSKLIDPEILIEIEVTAILG
>NZ_CP043329.1|WP_149075569.1|3474375_3477690_+|preprotein-translocase-subunit-SecA
MLNFISKLFGSKSERDVKSLRPIVDKINEEFQKLAHISHDELRAKTSEFKQRIQESLSEINGKITDIKNTVEQNPELSLHEKTAYYDEVDRLEKERNKKLEATLLEILPEAFAVVKETAKRFTEHETIEVSATPFDRELAAKKANVVINGEKAIHHNSWIAAGTEVKWNMIHYDVQLIGGMVLHQGKIAEMATGEGKTLVGTLPIYLNALSGMGIHVVTVNDYLARRDSEWNGPLFEFHGLSVDCIDKHYPNSADRRKAYQADVVYGTNNEFGFDYLRDNMTRTPEELVQGKLHFAIVDEVDSVLIDDARTPLIISGPIPRGDQHEFYDLKPRIERLVNTQRNFITNVLNEAKKQINEGKTGVEEGGLALLRAYRGLPKNKALIKFLSEPGMRQVLTKAENYYMQDQNKEMHKADAELYFIIDEKNNQVELTEKGIELITASGEDPHFFVLPDVGTEIADIEKSTISNEQKANQKDELIRDYSIKSERIHSVNQLLKAYTLFEKDTEYIIDEGKVKIVDEQTGRIMDGRRYSDGLHQAIEAKENVKIEDATQTYATITLQNYFRMYHKLAGMTGTAVTEAGELWQIYKLDVVEIPTHRPTSRTDMQDKVYRTMREKYNAVAEEIVELTKAGRPVLVGTTSVEISELLSRMLKLRGIKHNVLNAKLHQKEADIVAEAGKSGTVTIATNMAGRGTDIKLGPGVKEAGGLAIVGTERHESRRVDRQLRGRSGRQGDPGSSQFFVSLEDNLMRLFGSERIANLMVKMGIEDGEVIQHSMITSSIERAQKKVEENNFGIRKRLLEYDDVMNSQRTVIYTKRKNALFGERLDLDIENMVVDVIDDIVTEYKDANNYEGFKLELIRIFAIDTAITHEEFTGSNINKLSDIIFEEATEAYKRKSDAIAQQAYPVLKEVLDTRGQAIESIIVPFTDGTHGIQVAAPLKKSVETQGKEVVKAFEKNVVLALIDDTWKEHLREMDDLKQSVQNAVYEQKDPLVVYKMEAFNLFKGMLAGVNKEVVSFLFKGIIPTNDGHAAPVQEARQAPQTDMRQMKVSKPELARESNGVPVDDTRELQRTQPVVRHEDKIGRNDPCPCGSGKKYKNCHGLSAS

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	234311-234344	7	0.794
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP010386	Enterobacter hormaechei subsp. xiangfangensis strain 34399 plasmid p34399-121.660kb, complete sequence	23104-23137	8	0.765
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_AP014953	Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_2, complete sequence	93570-93603	8	0.765
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP027605	UNVERIFIED_ORG: Enterobacter cloacae strain AR_0093 plasmid unnamed1, complete sequence	66084-66117	8	0.765
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP013914	Serratia fonticola strain GS2 plasmid pSF001, complete sequence	106055-106088	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP022182	Aeromonas salmonicida strain S68 plasmid pS68-1, complete sequence	66349-66382	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NC_003276	Nostoc sp. PCC 7120 = FACHB-418 plasmid pCC7120alpha, complete sequence	213967-214000	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP022177	Aeromonas salmonicida strain S44 plasmid pS44-2, complete sequence	14287-14320	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP017144	Aeromonas salmonicida subsp. masoucida strain RFAS1 plasmid unnamed1, complete sequence	50557-50590	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP022171	Aeromonas salmonicida strain S121 plasmid pS121-2, complete sequence	63733-63766	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP038909	Piscirickettsia salmonis strain Psal-009 plasmid unnamed1, complete sequence	43641-43674	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	MN693074	Marine virus AFVG_25M380, complete genome	540-573	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	KJ010489	Enterococcus phage IME-EFm1, complete genome	29393-29426	9	0.735
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP013914	Serratia fonticola strain GS2 plasmid pSF001, complete sequence	106062-106095	10	0.706
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	MK765621	Tortoise microvirus 53 isolate 53_SP_156, complete genome	3188-3221	10	0.706
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	MK765603	Tortoise microvirus 51 isolate 51_SP_173, complete genome	3188-3221	10	0.706
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	LC377538	Staphylococcus aureus plasmid pNTUH_3874 NTUH_3874 DNA, complete sequence	6598-6631	10	0.706
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP047806	Staphylococcus aureus strain UP_1654 plasmid unnamed, complete sequence	8279-8312	10	0.706
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	234318-234351	11	0.676
NZ_CP043329_3	3.4|1153020|34|NZ_CP043329|CRT	1153020-1153053	34	NZ_CP024792	Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence	287654-287687	12	0.647

1. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 7, identity: 0.794

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
taatttttaatttttaatttttaattgattcacc	Protospacer
 ******** **** *********** * * * *

2. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP010386 (Enterobacter hormaechei subsp. xiangfangensis strain 34399 plasmid p34399-121.660kb, complete sequence) position: , mismatch: 8, identity: 0.765

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
aaatatggttttttcgatttttaatttaataagc	Protospacer
.*** *   .**** .******************

3. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_AP014953 (Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_2, complete sequence) position: , mismatch: 8, identity: 0.765

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
aaatatggttttttcgatttttaatttaataagc	Protospacer
.*** *   .**** .******************

4. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP027605 (UNVERIFIED_ORG: Enterobacter cloacae strain AR_0093 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
aaatatggttttttcgatttttaatttaataagc	Protospacer
.*** *   .**** .******************

5. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP013914 (Serratia fonticola strain GS2 plasmid pSF001, complete sequence) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
taatttttaatttttaatttttaatttttatcgt	Protospacer
 ******** **** ************     *.

6. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP022182 (Aeromonas salmonicida strain S68 plasmid pS68-1, complete sequence) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
tgttttttaatttttaatttttaatttaaagtgg	Protospacer
 . ****** **** ************** . * 

7. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NC_003276 (Nostoc sp. PCC 7120 = FACHB-418 plasmid pCC7120alpha, complete sequence) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
taattttgaattttgaatttttaattttgaattg	Protospacer
 ****** * ***************** . *   

8. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP022177 (Aeromonas salmonicida strain S44 plasmid pS44-2, complete sequence) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
tgttttttaatttttaatttttaatttaaagtgg	Protospacer
 . ****** **** ************** . * 

9. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP017144 (Aeromonas salmonicida subsp. masoucida strain RFAS1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
tgttttttaatttttaatttttaatttaaagtgg	Protospacer
 . ****** **** ************** . * 

10. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP022171 (Aeromonas salmonicida strain S121 plasmid pS121-2, complete sequence) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
tgttttttaatttttaatttttaatttaaagtgg	Protospacer
 . ****** **** ************** . * 

11. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP038909 (Piscirickettsia salmonis strain Psal-009 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

gaatt---tttacttttgaatttttaatttaataagc	CRISPR spacer
---ttcagtttatttttgaattttgaatttaatcgtt	Protospacer
   **   ****.*********** ******** . .

12. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to MN693074 (Marine virus AFVG_25M380, complete genome) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaa-------tttaataagc	CRISPR spacer
gaattttttattttgaatttttaacaggttcttt-------	Protospacer
********  **************       ***       

13. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to KJ010489 (Enterococcus phage IME-EFm1, complete genome) position: , mismatch: 9, identity: 0.735

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
ttatttttccttttgattttttaattaatccatc	Protospacer
  ****** ******* ********* * . * *

14. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP013914 (Serratia fonticola strain GS2 plasmid pSF001, complete sequence) position: , mismatch: 10, identity: 0.706

-------gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
taatttttaatttttaatttttaatttttaattt-------	Protospacer
        ******** **** ************       

15. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to MK765621 (Tortoise microvirus 53 isolate 53_SP_156, complete genome) position: , mismatch: 10, identity: 0.706

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
atttttttatttttgattttttaattttttttgt	Protospacer
.  ******.****** **********  *  *.

16. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to MK765603 (Tortoise microvirus 51 isolate 51_SP_173, complete genome) position: , mismatch: 10, identity: 0.706

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
atttttttatttttgattttttaattttttttgt	Protospacer
.  ******.****** **********  *  *.

17. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to LC377538 (Staphylococcus aureus plasmid pNTUH_3874 NTUH_3874 DNA, complete sequence) position: , mismatch: 10, identity: 0.706

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
cccctattacttatgaatttttaattgaatcaat	Protospacer
   .* ****** ************* *** *..

18. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP047806 (Staphylococcus aureus strain UP_1654 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
cccctattacttatgaatttttaattgaatcaat	Protospacer
   .* ****** ************* *** *..

19. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 11, identity: 0.676

-------gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
ttttttttaatttttaatttttaatttttaattg-------	Protospacer
        ******** **** ***********        

20. spacer 3.4|1153020|34|NZ_CP043329|CRT matches to NZ_CP024792 (Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence) position: , mismatch: 12, identity: 0.647

gaatttttacttttgaatttttaatttaataagc	CRISPR spacer
taatttttaatttttaatttttaataccccgtag	Protospacer
 ******** **** ********** .  .. . 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2764703 : 2771617	7	Synechococcus_phage(83.33%)	NA	NA
DBSCAN-SWA_2	3254254 : 3331404	58	Acidithiobacillus_phage(36.36%)	tRNA,holin,protease,transposase	NA
DBSCAN-SWA_3	3386789 : 3444875	54	Myxococcus_phage(25.0%)	tRNA,integrase,protease,transposase	attL 3386552:3386611|attR 3398809:3398879

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP043329|2764703:2771617|DBSCAN-SWA
ATTACATGCCAAATCTTGATTTTAATACATTATAATTTTGTTGAATTTCTGAAGCTGTTAATTCGCGATTATAAATTCTAAGATTACCATATTGCATATTTCCGAGAAAACCTCCATTGTTCCAACTACATAATCTTAGGTTGTTGTTAAAACCAGGAATATTAGCATCAGTTCTTACTACCGGAGTTAGTACCCCCACATCAACACCGTCTATATAAATTTTATTTGTAGATAATAGGCCTGAACTTTTCATAACAAATGTATAATGGTGCCAATTACCCACTAAGTTTAAATTCGAAACTATAGCAGCCGATATTCCAACTACATTACCCCCTCCGGTATTATAACCGAGTGTTCCACTTTCAGTCCATACATCATAAGTAGTGAAACCAAAAAACATCCCTCCAGAGCCAGAAACCCATTTCACAAAACCCTCTATGGTTAGTATGGTTGCCGAGCCGAATGAATTAGAAGTGATATCGGCATAATCATTTACACCATCAAAAACTAAAGATCCACCATTTGAACTATTAAAGGCGACCCCATTAAATAAAGTACCATGATTACCGTTACCACTTAAATCTGTCCAAGTAATGCCATTTCCAGGGTATGATGACGTATTACCAGCATCTAGATTTACAATTAAACTGTTAGTAACCAAATTACTAGTGTTAATCTTAGATTGATAAAAGCTAAAAGGCATTACTTGCGAAAACCCTAATGAAGATGATAAGAATAGAAAGGAGAAGAAAGATGATTTAAGTTTTTTCATATTTAGAGTATTTTAATGCCGAATTTTAGTTTATAAATTAAGTTATCTAACCCAATACCATAAAATACCAGGATTGGGATTTGTTGTGCCCCCACCCGCATTATCTATCCAAGGAGTTGGAATCCAGCCAGTACAACGAGAAACTAAGGTTCCCCACCAATTGCCTCCGCCATTATCGGTAGTTATTTGTCCGCAATCATTTTGGTACCATGGCATTCTTTCGCTAATACCATTATCATTTATATAAGCCCAATTACCAAATTTGGTATTAATTGTAATGTTGGTTTGAGAATTATCGGTTTTCACAAAACTATAATTACCGTTAGCAGTCCAAATTGCACCATGGCTTCTTCTTGTTGTTGCATCAATCATGTATTGAAAGCCGGATGCACTTCTTTTGATAAAATCTGCCCAGCCAATGATAGAATAATTAGCTGTTGATGTACTGATGACATCTGCAGTATTAGTAAATGGCATAGATGTATTTAATGAAATTGCATTTTCATATGTCCAGCCAGCACTATTAGAATTCTTTAAAATCAAAGTCCAGCCACCACCATCAGTAGTCATATCTGCATAAATTTGAAATGGCGTATTACTATTGATATTTACATTCTTAATCCAATAAATACCATCTGTAGAACTTGGATAATCTCTCTTAATTTGAAAAGCACTGCTACCAGCTGTAGCACTTGTTTTACCATCGCCAAAGCCCGACGCATTATTTCTCTGAATAAAACTCATAGGCATAACCTGAGCATGTGCCAAAAAAGGAATAATTATTATAAAAAGTAGAACGTTTAATTTAAGATGGTTCATTTTTGCATATTTAAATTAAAGACCAAACCTTGATTTTAATGCATTATAATTTTGTTGAATTTCTAAATCCGTAAGTGTTCTATTGTAAATTCTAACTATAGCAATTCTTCCATTCAATCGGGAATTAACATCAGATCTAGTACCGCCAAAATTTAATACTCCGTATGGATTTTCATTTCCGGTTCCAGTATGTTTAGTTTGATTGATAAACAGATTAGCCCCCTTAGTAATACAGAACCTATACCAAGTATTTAGAGGAGGTTGTCCTACTGTGCCGTAACTTCTTCCTCCTAAACCATTACCATCAGTTCTAAACGATGAACCATTGAATGTGTAAGATCCTGCATTCCCATTGTAAGATAAGATATCTCTCTCTCCACTGCTCCGTGTATCATAAATCCAGATTTCTAAAGTAAAATTAGTGTAGGATGATAAATTTATACTTGATACAATATCATCAGCACCGTCTAATCTTAAATATCCCCCATTGCCACTATTGTAACTAACACCATTTTGAAGAGTTGCATGATTGCCATTACCACTTAAATCTGTCCAAGTTGTTCCAGTTCCAGAGTAAGATGCTGTATTACCTGCATCTAGGTTTACAACTAATCCAGAATTTATTATGGGGCCGTCAGCTATAGTAGCTTGTGGTGGTTTTCCTAAAAAACTTACTGGCACTACTTGTGCTTTTCCCAACCATGGAGTTATTAGAAAAAGAAATAAGATAGTTGATTTTAATTGTTTCATTGTGTAGTTTACTTAACTAATATCCAAACCTGGATTTAAGTGCTTCAAAATTGTCTAGGACTTGTTTTGCTGTTAAAACAATGGAGTAGGCTTGGGCAATGGCAATATTTCCTGCAAACTTTGGGTCGCCAGTAACATTTGCGTTATAAGCAATACCAATTTTAGAAGGTCCAGTTAAGGACCCCGTAGAGGTAGTAAAAGTTTTATCTAAAACACCATCAATATACAAATTAACCTCTCCAGAAGTAGCATTTCTAGTTACTGTAATATAATGCCATAAGTTATCATTGATAGATTTTGTGGTGTAGGATGTAATGTCGTTTGCTCCGTTTCCAAAACCTAATTTACCGTTACCCATTACTACTGCATAATCATTAGTACCGCCGGGCATCTCACCTCCAAAAATAGAATAAGCCGTATAAAATTGGCCTGATCCACCCCCAGTCTGACTGGTTTTAATCCAAGCTGCCCAAGTCATATTATCTTGTACTGGTCTGGCAAGAGAGAATCCATTCGTACCATTAAAATTGAAATAACTAGCTGCTCCATTAACTGTGAATGTAGGATTACTTGGATTACTATACATAGTTGCATTATAGGTAGTTCCTCCAGTACCTTTATTTATCCAAGTGGTTCCGGTACCTGCATAGCTGGTTATATCTCCCGCATCTAAATTTAAAATTAGGCTATTGGTAACAATTGAAGGCACAGCGTTTCTTTGTAAAAAACTTATAGGTACTACTTGTGCAGCTCCTAACAATGGGACTAGTAGAAAAAGAAATAAAATACTTGATTTAATATTTTTCATCGTATTAAATTTACAAACCGTATTTAGCCTTGTTAGCATTAAAATTTTGTAGAATTTCTGAGTCGGAGAGCGCTCTATTATAAACTAATATTTGGTAAATCTGTCCGTTTGGCCCCCAAACCTCGCTACCAGTTACTCTATGTCCAATTCTAGCTTCGGCTATACCAGTGTTTATGGAAGCAGAAACACCTGATCCCTGCGAAACACCATTTATCCAAAATTTATGCAGTGTATTAGCATGAGTATAAGTTACTGCAAAAAATAATTTGTTGCAGTAGCAACCGTGGCACCCTGCCCTGGGTATGTGGCCCATGTGTGTGAATTTAATTGGCCATTAGATAATGCTAATCCAAATGTTTGATTGTTAGACGTAGAGCCCCAATGTATAATGTGATTTAAAATAATAAAACTTGTTGGGGTTTTTACAAAAGCAATAATTGTTCTATCGCTAGTACCTATGGGTAGCTTTGATGGATTTAAGCTAACATATTGGCCAGAACCGTTAAAATTAAAATATCCACCATTACTTGAATTGAAAGTAACTCCGTCTATTAAAGTACCATGATTAGCAGTACCACTTAAATCTGTCCAAACAGTACCAGTGCCAAGGTAAGACGCTTGATTACCTGCTTCTAAATGCAAAACCAATCCATTAGTATATGGAGCTTTTGGTATATAGGAGTTATTACTTCGAAATAAGCTTTGTTGGGCTTGTAAGTTTAAGTTAAACACTAAACAAACTAGAAGGGTTAATTTAAATTTCATGGCTGTTATATTATTAAAAAATAACTTCTATACTTAAACTAATCGATAACTTTTTACTATAAAATTGCCCATCTCTAATGATGTAGGATGGGCAATTTGTTTTTAATCTTAATATTTGTTAGCTGTAATTATTAAGATTTCCATTAGAAATTTTGCAAAATAGCTGCGTAATACGTTGTGCCATCATAAATAATGGTTACAATATCAGTTTTACTAGCCCCAGTTGTTATTGTAGGTATAGTACCCCGCTCCATTTCCAATTTGCAGGAAAAGTTACTGTTTTAGAACCAGTTCCGTCTTGTGTAAACTCTATAATGTAAGTTCCGGGAGTTGGATTTGTAAAAGACAGCGTACTAATATTAGTCCCTAAAGTAACTTGAAATAAGTTTCCATCAGATAAATTAAGCGTTGTTGTTGCCGCCGCTGCAACAGTTGGCGCTGTAATGGTATATTTTTTGGCTGTTACGCTACCTGCAACACCTACACCACCATTAACTACTAATGCTCCTGTGGTAGTACTAGTTGAAGCTGTTGTAGGTAAGACTGATACTTTACCAGGCGCAATTTCAAAAATTGAAGGCGCAACATTATTTGCAGTAGCTATACGGAATTTTAGAGTTGATATACGAGCTGGATTAGTAGTACCCTCATCTGGGAAATCATTAAACATCCCTGTATTTCTTGCCCAATCACCTCCTATAAAAGAGAATCCAACTGCCTCATTGTAAGTACTTCCAGCTGCGGCTCTCATTGCAGTCGCTGTTGGCGCCGCCCAAGTAGGCAAACCGCTGGCTAGGGTTAATACTTGTCCATCTGACCCTTTCCCTAATCTTGTTCCTGTACCGCTGGTTCCACCATAGATGATATCGCCTGAAGCAGTCATCGGAGATAAAGCATCAAAAGCAGCCGCTTTAGTAGTTGCATTAGTACCACCATTAGCGATTGATAATGTACCAGTAACACCAGTAGCTAAATTTGTTGCGGCTGCAGCAGGTGCTGCAGTACCATATCCTTGCCCAACATTCCAATAGTATGTAGAGCCATTATAATAAAAACTAACAATATCTACAGCATTACCTGCCGTTGATAAACCAACAGTAGTTGTTGAAGTAGAGCCTAATACTCTATGTGTACCTGAAGGTAATGTTAGAGTAGCGCCACCGCCTGCAGGTTGTGTTACTACTAATGTACCATAGGTACCGCTTGCTGGTGCAGAACTAAAAGCTAAAGTGCTATTTCCTGTTAATGTTACCGAAGCATTTAACCCTTTAGCTGGATCCCATGTAATGGTAGAGCCTGAAGGACTTATTGGGTTTGGCGTTGAAGCATAAATAGGTGAAGTAACCGTTCCGGTAAAGGTTGGTGAAGCTAATGGTGCTTTTGCATCTAAAGCAGTTTGAGTAGCCGTTGAAATTGGTTTACTTAAATCTGTAGTATTATCTACATTACCTAAACCTACCATGGTTTTTGTTATACCTGATACTGTTCCAGTAAAAGTTGGTGAAGCTAATGGCGCTTTTAAAGCTAAGTCTGTATTTGATGCTTTTGCATCTAATGCTGTTTGAGTAGCTGTTGAAATCGGTTTACTTAAATCTGTAGTATTATCTACATTACCTAAACCTACCATAGTTTTTGTGATACCTGATACTGTTCCAGTAAAGGTTGGTGAGGCTAATGGTGCTTTTAAAGCTAAAGCAGGTACTGTTGGAGATTCTGCACTTCCTGCTAAATCACCTGTTAGTTTAATAATGCCTTTAGTAGAACCATCAGCAGTTGGCACCCCTCCTGATGTAAAAGAATTATCTACATACTGTTTAATCGCTTTTACAGTTGGGTATTTATCATCAGAACTAGCATCCTCTGTAATATCGGTTGATTTATTCGATTTATCTTCTTTAGTTAACTCTGCTGCTTTTGCTCTATTCTCTTCAGCCACAATTGCATCGGCATTAGCTTGCTCTGCAGCTCTTGTTATTTCATTTGAAATTGCAGTTGAATTATCAGACTCCGCCAATTTAGCTCTAGTTTCTTCAGCTGCAATTGCATCGGCATTAGCCTGCTCTGCAGCTTTTGCTCTTGTTATTTCATTTGAAATTGCAGTTGCATTAACTTCTAAACCAGGTACCTTTGGTAAATCTGCAGTTCCACCTAAATCTCCCGCTAATTGTATTTTGCCTTTAACTGCAACACTAGCATCCGCTAAAATAGATCCATCAGCACCAGCTGGGCCTTGTGGCCCGATAGGTCCTGCTGGACCAGTTTCCCCTGTTTCTCCTTTGTCTCCTTTTAATCCTTGTGCACCGGCTACTCCATCTGCACCTGCTGGACCTTGCGGACCTGCTGGACCAGTTGCTCCTGTTTCTCCCTTATCTCCTTTCAATCCTTGTGGACCTTGTAGACCGATAGGGCCAGCTGGACCTTGAGGGCCTGTATCTCCTTTTATACCACTTCCTACTGAAGCGAAGGTATTATCTACATAACTTTTAACAGCTTTTTGTGTTGGATACAATACATCGCTTGTTCCTAAAGCAATAGACGAAGACTTATTAGCTATATTCTCTTTAGTATCTAGAGCAGTTTTTGTTGCATTACTTACAGGTTTATTTGCATCACTGGTATTATCAACATTACCTAAACCTACTTTTGATGGACTTATTCCAGATGCTATTTTAACATCTGTTATGGCTCCATCAGCTAATTTAACTGTCGTGATATTTCCATCACTTACTGATGCATTTTCTGAGAATAGCGCATAAGGAACAGACATAAAGGGCTGCTCACTAATCTTCGTATAAGAAGCACATGCTCCTGTAGTATTTAAGCTTACTACCAATTTCTTGTTTCCTAAAGACCAGCGGATTTTATCAAATGCCGATGCATAACCTCCAGTTTTAGTTCCTGTTCCAATCATCAGGTTAACCATACCAAACATATCTGTTGTTGTTTGTATAGATTCTTGATATTCTACTTGTGATGATCCATCAACAATCTCAAAAAGCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP043329|2764703:2771617|2766308_2767043_-|WP_149075110.1|DBSCAN-SWA
MKQLKSTILFLFLITPWLGKAQVVPVSFLGKPPQATIADGPIINSGLVVNLDAGNTASYSGTGTTWTDLSGNGNHATLQNGVSYNSGNGGYLRLDGADDIVSSINLSSYTNFTLEIWIYDTRSSGERDILSYNGNAGSYTFNGSSFRTDGNGLGGRSYGTVGQPPLNTWYRFCITKGANLFINQTKHTGTGNENPYGVLNFGGTRSDVNSRLNGRIAIVRIYNRTLTDLEIQQNYNALKSRFGL
>NZ_CP043329|2764703:2771617|2768100_2768616_-|WP_149075113.1|DBSCAN-SWA
MKFKLTLLVCLVFNLNLQAQQSLFRSNNSYIPKAPYTNGLVLHLEAGNQASYLGTGTVWTDLSGTANHGTLIDGVTFNSSNGGYFNFNGSGQYVSLNPSKLPIGTSDRTIIAFVKTPTSFIILNHIIHWGSTSNNQTFGLALSNGQLNSHTWATYPGQGATVATATNYFLQ
>NZ_CP043329|2764703:2771617|2767861_2768164_-|WP_149075112.1|DBSCAN-SWA
MGHIPRAGCHGCYCNKLFFAVTYTHANTLHKFWINGVSQGSGVSASINTGIAEARIGHRVTGSEVWGPNGQIYQILVYNRALSDSEILQNFNANKAKYGL
>NZ_CP043329|2764703:2771617|2765516_2766293_-|WP_039454896.1|DBSCAN-SWA
MNHLKLNVLLFIIIIPFLAHAQVMPMSFIQRNNASGFGDGKTSATAGSSAFQIKRDYPSSTDGIYWIKNVNINSNTPFQIYADMTTDGGGWTLILKNSNSAGWTYENAISLNTSMPFTNTADVISTSTANYSIIGWADFIKRSASGFQYMIDATTRRSHGAIWTANGNYSFVKTDNSQTNITINTKFGNWAYINDNGISERMPWYQNDCGQITTDNGGGNWWGTLVSRCTGWIPTPWIDNAGGGTTNPNPGILWYWVR
>NZ_CP043329|2764703:2771617|2764703_2765474_-|WP_149075109.1|DBSCAN-SWA
MKKLKSSFFSFLFLSSSLGFSQVMPFSFYQSKINTSNLVTNSLIVNLDAGNTSSYPGNGITWTDLSGNGNHGTLFNGVAFNSSNGGSLVFDGVNDYADITSNSFGSATILTIEGFVKWVSGSGGMFFGFTTYDVWTESGTLGYNTGGGNVVGISAAIVSNLNLVGNWHHYTFVMKSSGLLSTNKIYIDGVDVGVLTPVVRTDANIPGFNNNLRLCSWNNGGFLGNMQYGNLRIYNRELTASEIQQNYNVLKSRFGM
>NZ_CP043329|2764703:2771617|2767059_2767851_-|WP_168199439.1|DBSCAN-SWA
MKNIKSSILFLFLLVPLLGAAQVVPISFLQRNAVPSIVTNSLILNLDAGDITSYAGTGTTWINKGTGGTTYNATMYSNPSNPTFTVNGAASYFNFNGTNGFSLARPVQDNMTWAAWIKTSQTGGGSGQFYTAYSIFGGEMPGGTNDYAVVMGNGKLGFGNGANDITSYTTKSINDNLWHYITVTRNATSGEVNLYIDGVLDKTFTTSTGSLTGPSKIGIAYNANVTGDPKFAGNIAIAQAYSIVLTAKQVLDNFEALKSRFGY
>NZ_CP043329|2764703:2771617|2768842_2771617_-|WP_168199483.1|DBSCAN-SWA
MLFEIVDGSSQVEYQESIQTTTDMFGMVNLMIGTGTKTGGYASAFDKIRWSLGNKKLVVSLNTTGACASYTKISEQPFMSVPYALFSENASVSDGNITTVKLADGAITDVKIASGISPSKVGLGNVDNTSDANKPVSNATKTALDTKENIANKSSSIALGTSDVLYPTQKAVKSYVDNTFASVGSGIKGDTGPQGPAGPIGLQGPQGLKGDKGETGATGPAGPQGPAGADGVAGAQGLKGDKGETGETGPAGPIGPQGPAGADGSILADASVAVKGKIQLAGDLGGTADLPKVPGLEVNATAISNEITRAKAAEQANADAIAAEETRAKLAESDNSTAISNEITRAAEQANADAIVAEENRAKAAELTKEDKSNKSTDITEDASSDDKYPTVKAIKQYVDNSFTSGGVPTADGSTKGIIKLTGDLAGSAESPTVPALALKAPLASPTFTGTVSGITKTMVGLGNVDNTTDLSKPISTATQTALDAKASNTDLALKAPLASPTFTGTVSGITKTMVGLGNVDNTTDLSKPISTATQTALDAKAPLASPTFTGTVTSPIYASTPNPISPSGSTITWDPAKGLNASVTLTGNSTLAFSSAPASGTYGTLVVTQPAGGGATLTLPSGTHRVLGSTSTTTVGLSTAGNAVDIVSFYYNGSTYYWNVGQGYGTAAPAAAATNLATGVTGTLSIANGGTNATTKAAAFDALSPMTASGDIIYGGTSGTGTRLGKGSDGQVLTLASGLPTWAAPTATAMRAAAGSTYNEAVGFSFIGGDWARNTGMFNDFPDEGTTNPARISTLKFRIATANNVAPSIFEIAPGKVSVLPTTASTSTTTGALVVNGGVGVAGSVTAKKYTITAPTVAAAATTTLNLSDGNLFQVTLGTNISTLSFTNPTPGTYIIEFTQDGTGSKTVTFPANWKWSGVLYLQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149075109.1|2764703_2765474_-	LamG domain-containing protein	Q5GQG3	Synechococcus_phage	5.8e-22	37.3
WP_039454896.1|2765516_2766293_-	hypothetical protein	A0A1D8KKY6	Synechococcus_phage	1.3e-08	38.1
WP_149075110.1|2766308_2767043_-	LamG domain-containing protein	Q5GQG3	Synechococcus_phage	1.1e-25	39.7
WP_168199439.1|2767059_2767851_-	LamG domain-containing protein	M4QPH6	Synechococcus_phage	4.4e-09	29.0
WP_149075112.1|2767861_2768164_-	LamG domain-containing protein	NA	NA	NA	NA
WP_149075113.1|2768100_2768616_-	hypothetical protein	M4QP69	Synechococcus_phage	9.5e-13	61.7
WP_168199483.1|2768842_2771617_-	hypothetical protein	Q19XF5	Mycobacterium_phage	1.0e-07	57.6

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP043329|3254254:3331404|DBSCAN-SWA
ATTAATCATCTTTTTTAAAGCCCCCGAACACCATTTTAATAACAGCCAGAACCAAAGCAAATAATAAAGCCGATAAAAAGCCAGAAGTATTAAAGCTAGTCATCACTTCATCAACCAGTAAAACCATTAAAACGGTAATGATGAAAGACATCAGCCCCAGCGTAAGAAAATTAATGGGGAAAGTAAAAATCCTTAAGATAAAACCAATAGTAGCATTAGCTAAAGCGATTAATATACCAGCTAAAACCGCTGATAAATAACCATCCACACTCACTCCTGGAATTAAAAATGCAGCAATAGCTACCGCTAAGCCCATCAATAAAATTTCTATTATTAAACTCATCACAAAAGATTTTAATCCTAATCTAACAAAATTTAAGCCATTTGGGTAGGTTTTTAGTGATTAGTTGGTTAGGTTGTTAGTCAATAGTTGGTTAGTTGGTTAGTTTGTTAGTGATTAGTTGGTTAGGTTGTTAGTCAATAGTTGGGTAGGCCCGATAGCTATCGGGAGTTGGTCCTAAATATGGGTCAAAGGATTTCTAGTAAATGAGATGTGATTTTAATATGTCCACTGTTAGCCTTTTTACTTCCGCTTTTCGCTTTCCGCCTTTAATCAAGCCACTTGATAATCAAAATTTTAAAATCTGAAAAATTTTATTACATTTGCAGTGTTGAAAAAAGAGGGGGCTAATATTGTCCCCTCTTTTCATTTATCCAAAAACTATTGTCATGGGTGTTGAACAGAGAGTTAGAGCTTTAGCAGAAGAAAAAATAGCAGACAGACCTGATTTATTTATTGTTGAAATTAAAGTCATCAATAACACCAAAGTTATTATTCTTTTAGATGGCGATAATGGTGTAGGAATACACGATTGCGCTTTGGTAAGCAGACACGTTGGTTACCATTTAGAAGAAGAAAATTTGCTAGACCACGCCTACAATTTAGAAGTAAGTTCGCCTGGTTTAGATACACCTTTAATTTTGGATAGGCAGTTTGCTAAAAACATAGGTAGAAATGTAACCGTAAAACACCTTAACGGTGATAAAGTGGAAGGCACTTTACTATCGGCAGATGAAGAAAGCATAACGGTAGCACATCAAGTAAAAGCTAAAGGTGCAAAAACCAAAAAAGCAGAACTTGTAGAAAGTAAAATTTTAAAAAATAGTATCGCTGAAGTAAAAGTAAGCGTATCTTTTAAATAGTAGCATTAATAAAATATTGATGAGAATAAAATGAATAGCATTAACTTAATTGATTCATTTCAGGAGTTTAAAGACTTCAAAAATATCGACAGACCAACCGTTATCAGCGTGTTGGAAGAAGTGTTTCGCAGTATGCTGCGTAAGCGTTTTGGTACCGATGAGAATTGTGATGTGATTGTGAATCCTGATAATGGGGATTTGGAGATTTGGAGAACTAGAACCGTTATGGAAGATGGTTTCTCTGAAGATGATGACCTGGAAATAGAATTGGCAGATGCACATAAAATTGATGCTGATTTAGAAGTTGGTGATGATTTTATCGAGCAAATCACTTTAGAAAGCTTTGGAAGAAGAGCTATTTTAGCTGCTCGTCAGACTTTAGTATCTAAAATTTTAGAATTAGAGAAAGATGAGATCTTCAAAAACTATAAAGATAGAATTGGTGAGATTGTAACTGGCGAGGTTTATCAGGTTTGGAAAAAAGAAACTTTAGTTTTGGATGATGAGGGTAACGAGTTGATTTTACCTAAAACAGAACAAATTCCTGCAGATTATTTCAAAAAAGGCGATACCGTTAGAGCGGTAGTGCTTAAAGTTGAAATGTTAAACAGCAATCCAAGAATCATCATTTCAAGAACAGCTCCTGCATTCTTACAAAGATTATTTGAGCTTGAAGTTCCTGAGATTTTTGATGGCTTAATTACCATTAAAAACATCGTTCGCGAGCCAGGAGAAAGAGCAAAAGTTGCAGTAGAATCTTATGATGACCGTATAGATCCAGTAGGAGCTTGCGTAGGTATGAAAGGTTCTCGTATACATGGTATTGTTCGTGAATTGAAAAACGAAAATATCGATGTTATCAACTTCACCAATAACATCTCTTTATACATCCAAAGAGCTTTATCGCCAGCAAAAATATCATCTATTAAATTAGATGACGAAACCATGAGAGCAGCCGTTTACTTGAAACCAGACCAGGTTTCTTTAGCTATCGGACGTGGCGGACATAACATAAAATTGGCAGGTAAATTGACGGGCTACGAAATAGATGTTTACCGCGAATCATCAGAAGAAGACGAAGACGTAGACTTAGAAGAATTCTCTGATGAAATTGACGGCTGGATTATAGACGAATTTAGAAAAGTTGGTTTAGATACAGCTAAGAGTGTATTAGCACTTAATGTAAATGAATTAGTGAAACGTACTGATTTAGAAGAGGAAACTATCGAAGAAGTACTAGAAATTTTAAGAGCAGAGTTCGAATAATTTTAGATTTGCATTAAGTAAACGTACTTTTGTTTTAAAATTAGAATAGAAAGATCATAATAGATGTCAGAAGACAAAAAGTTAGGAATATTAAAAGTTGCAAAAGAACTAAACATCGGTATTGGTACGATAGCTGATTTTTTAGGTACTAAAGGTTTCTCTGTAGAAGCCAAACCTAATACAAAGCTAACCGATGAGATGTACGGAGCTCTTTTAAAAGAATATCAGGGAGATAAAATCCTGAGAGAAGAAGCTAAAAACATTGTTATTGGCAAGATCCGTCGTGATGACGCTACTCAGGTGAATGAAAAACCAGAATCTACTGAAAGACAAGAATCTCAGGACTCAGACAATGAAATCCTGATAAAGAATACAGGTTCAGCAGTTCCGGTTTCACAAGAGACTGAGAAAGTAGAAGCTCCAAAAGCGGAGCCTGCGCCAAATACTGGCGGTGTAAAAATTATTGGTAAAATAGACCTTGATAGTTTAAATTCTAAAACTCGTCCTGACAAGAGGAAAGAAGAAGTAAAACCGCAGGCAGCGGCACCTCAAGAAGTTAAAAAACCTGATGCACCACAACCAGTACCGGCTCCAGAGCCAGTTGCTGAGGTTGTAAAACCTGTTTTAGAAGTTAAACCAGAGCCTAAAGTTGAGGTTAAAGCAGAACCAGTTGCAGAGCTTGTAAAACCTGTGGAAGAGGTTAAACCAGAGCCCAACGTGGAGGTTAAACCAGAGCCTAAAGCAGAAGTTAAACCAGAGCCAGTTGCTCCTAAGGCAGAAGAAATTAAACCAGAGCTTAAAGCTGAGGTTAAACCAGAGCCAGTTATAGAGCCTGTAAAGCCTGCTCAAGAAGAGCCTGTTGATGATGAAGTAATTAGAGCTAAAGCTCAGCAATTAAGCGGACCTAAAATTATTGGTAAAATACAACTACCTGTTAATAAGAAAAAAGATCAGCCTGTTGCATCTTCATCAAACCCTAACACGGCAGATAATAAGAGAAAACGTAAGCGTAAGCCTGCACCAGGTGGCCAGCAAAATAGGCCAGGTGGCGGCGCTCCAAATACCAACCCAGGAGGAGGGCAACCTGCTACGGGTGGTGGTTACCAAGGTAACCGTCCACAAGGTGGAGGCCCAGGACAGGGAGGTCAGAACAGACCTGCTTCAGGCGGACAAGATAATAAAGGCGGAAGACCACCACACAAAAGAGGTCAGCCTTTACCACCTAAGGTAGAGCCTACAGAAAAGGAAATCCAAGACCAAATTAAAGCTACTTTAGCCCGTTTAAGCGGTGCCGGTAAATCTGGTAAGTTTGCACAACGTTCTAAATTGCGTGGGCAGAAGAGAGATAGAGCATCAGCAAATGCCGAAGAAGCAGCATTAGAACAAGAATTACAATCTAAATATTGAAAGTAACAGAATTTGTTACTGCCAATGAGTTAGCTAACATGATGGATGTTTCTGTTACAGAAGTTATCTCTACATGTATGAGCTTAGGAATGTTTGTATCTATTAACCAAAGGTTAGATGCAGAAGCCTTAACCATTGTTGCTGATGAGTTTGGATATGAAGTTCAGTTTGTAAGTGCAGAGGAAGAAGAGTTTAATTTAGAAGAAGAAGATACAGAAGAAGCCTTAATCCCTCGTTCTCCAATTGTTACCGTAATGGGTCACGTAGACCACGGTAAAACATCTTTGTTAGACTTTGTGCGTAAAGCCAATGTTATTGCAGGTGAAGCCGGTGGTATTACGCAGCACATTGGTGCATACGAAGTAGTAGTAGAGGGCGATAAGAAAATTACTTTCTTAGATACACCGGGTCACGAAGCGTTTACCGCAATGAGGGCTCGTGGTGCTAAAGTAACAGACGTAGCTATTATTGTAATTGCTGCGGATGATAGCGTGATGCCTCAAACCATTGAAGCAATAAACCATGCACAAGCGGCAAGTCTTCCAATTGTATTTGCGTTTAATAAAATAGATAAGCCAGGTGCTAATACCGATAAGATAAGAGAACAACTAGCTGCTATGAATATTTTAGTAGAAGAATGGGGTGGTAAATACCAAACTCAGGAAATTTCTGCTAAATCTGGCTTAAACATAGATAAGCTATTAGAAAAAGTATTGTTAGAGGCAGAATTATTAGACTTAAAAGCTAATCCTAATAAGAGAGCTGTAGGTACAGTAATTGAAGCACAATTAGATAAAGGTAGAGGTTATGTAGCTACAGTTTTAGTAGAAGCAGGTACTTTAAGAGTTGGAGATCCGATATTAGCAGGTTCTTACAGCGGACGTGTTAAAGCGTTATATAATGAGCGTGGTAATCGTGTAGAAAAAGCTGGTCCAGCGGCACCAGTTCAAGTATTAGGTTTCCAAGGTGCACCACAAGCAGGTGATAAGTTTAACGGTGTAGAAAGCGAACCAGAAGCTCGTGATATTGCAAACAAACGTTTACAATTACAACGTGAGCAAGGTTTAAGAACCCAGAAACACATTACACTGGATGAAATTGGTCGTCGTTTAGCTATTGGTAACTTTAAAGAGCTTAACATCATCATCAAAGGTGACGTGGATGGTTCTGTTGAAGCATTATCAGACTCTTTACAAAAATTATCAACCGAGGAGATACAAGTTAAAATTGTACACAAAGCAGTTGGTCAGATATCAGAATCTGATGTATTATTAGCTACTGCATCTGATGCTATTATCATTGGTTTCCAAGTTCGTCCATCAGCAGGAGCTCGTAAGTTAGCAGAGGCAGAAGAAATAGATGTAAGATTATATTCTATTATCTACAAAGCTATTGATGAGATTAAAGCTGCTATGGAAGGTATGTTGGCACCAGAATTTGAAGAGAAAATTGTGGCTAATGTAGAAATCAGAGAGACCTTCAAAATCACGAAAGTGGGAACAATTGCAGGTTGTATGGTTCTAGATGGTACCATCAACAGGAACAGCAAAATCAGAATCATACGTGAGGGTGTAGTTGTTTACACTGGCGAGTTAGACTCTTTAAAACGCTTTAAAGACGATGTTAAAGAAGTTAACCGTGGTTATGAGTGTGGTTTAAATATCAAGAACTTTAATGATATTAAAGTAGGAGATATCGTAGAAGCTTACGAACAAGTAGAAGTGAAAAGGAAGTTGTAATTTCCTTTTTTAAATATTAAAATTTAAAGAGGCTGTCTCAAATTACCATTTTGTGTCAGGCTGAGCGGAGTCGAAGCCTTTTCTAAGCATATCAGAGAACATTTCGACTCCGCTCAATGTGACAGATACTATTTTTGAGACAGCCTCTTTTTTTATGCCTGATTTATTATTTCTTTTAGTTTTAGTTCGAGGTTGGAGATAGTTTGTATGATATATTCTGCCGCGGTATCTTGGAAAGGATTTTGAGAAATAAAATCTAGATACAATTTAGGGTCTTTATGAAGTCTTTCTACATCTTCAGATAGTGTGTTTTTAAACTCATCAAAGAAAATGATGCTGGATGGCTTGAATATATTGGGCTCGGGTTTTTGTGCACTACCCCAATAAATAGGGATGCAGCCTGCAGCAAAAGACTCAAATAATTTCTCGGTGGTATAACTCTCCTGATTTGTATTCTCTGGACAGATATTAAATTTATAGTTTTCTAAGAATTTAACCTTATTATTGGCAAATTCGGTTTGCAATCTAGCTGTATTATTAAATAATTTGCCAGCGCAATCAACGGTTTCTATAGGATTAAGGGTATTAACTATTTTCTTTCTGATTCCATTCTCATCATGCCTAGCAATTAGACTACAAAATTTTTCACGTACTATAGGCTTGTTGTTTTTGTAATAGTTTAACTGCTTAAGTTTTTCTTTTGCCTTTTCTAAATCAACGGTGGGTTCAAAAAAGTCGAGTATCCATAAGGGTAACCTGAAATATTTTTCGTGTTGCAAATCATCAAAACCTAATGCTAAATCAACCTCAGGTAAGCAATAGTCATGATATTTTTTGAAGCGTGACATAGTTTCGCCTGAGAAAAAGATATTAATTGCTGCTTTTTGCTTTTTTAAGACATATCTAGGGCCAAAAACCGAGAAAAAATTAATGCTTTTATTCTTCGGATTTAGGTTTCTATCAACGATGAATTTCTGTAACCAAAAATTATTATAGTCTTCTATCTCCCAAAAATTGTAGAAACTTATGGTTGAATTTCTAAATATCTTCTTTTCCTTTAGATATTTTTTATGCCGTTTAGCTAGTAAAAGAAAGTATTTCATGCCTTTCTAATGATTAGTAAATTCTTGCATGTTAATAAGCTTCTTATAAAGACCCTTATGTTGGGTTAGCTCTTGATGAGTGCCTTTTTCTATGATTTTCCCATTTTCTAACACTATAATTTCATCGGCATTTTGTATGGTACTTAGCCTATGAGCTATAATAATGGTTGTTCTATTTGCCATTAGATGGATTAATGCCTCTTGAACTAGTTTTTCTGATTCTGTATCTAATGATGATGTTGCTTCATCTAATAGCATGATTGGCGGATTTCCTAAAACTGCTCTTGCAATACAAATTCTTTGTTTTTGACCGCCTGATAGTTTAATTCCTCTATCACCAACATTTGTTTGATAACCCTTATCTGTTTTCGAAATAAACTCGTGAGCGTTGGCAATTTTTGCGGCCTCTTCTACTTGTTCTAAAGTAAATCCTTGGCGCCCAAAAATGATATTGTTTGCAATGGTATCATTAAACAGGATAGATTCTTGGTTAACAATACCCATTAAGTTTCTTAAAGAATATTGAGTTATATTTTTTATATCCTTACCATCTATAGATATTTTACCTTTTTGAGGGTCTATAAAACGTGGAATCAAATCTAATAAGGTAGATTTTCCAGCACCAGAGGGGCCAACAAGGGCAATCGTTTTTCCTCTAGAAATTTGTAAGCTTAATTGATTTAAAACGTGTTTTTCTCCGTAAAAAAAGTCAACTTCTTCAAAGTTAATAGCATGTTTAAACTCAGCAATTTCAGTAGCATCTTCATCATCAGTAATGATGGATGGAGTATCAATAAGCTCTAATACGCGTTCACCAGCAGCTATGCCTTGGTAAATATTACTGAAAGATTCAGAAATAGCTTTTGCAGGACGTAATAATTGAGAGAAAGCACCAATATAAGTAATAAACCCTGCTGCAGTAATATTAGAATCGTTTTCAAAAACTAAAGACCCCCCATAAATTAAAATTCCTGATAAGGTAAGTACACCTAAAAACTCTGAAACTGGAGAGGCCAATTGTTGTCTTTTGGCGATAGATTTATTAATGTTGGAATAGTAATTATTTTCTTTATTAAATTTCTCTTGAGTGTAACCCGTTGCATTAAAAGCTTTGATAATACGCATTCCACTGATAGCTTCATCAACCAAACTCACCATGATACCAAAAGAGCTTTGCGCTTCTGTAGCTTGTGCTTTTAGTCTTTTTACAATTTGAGCTATTACTAAACCAGATACTGGTAATAGCAAAAGGGTGAAAAATGTAAGTTTAGCTGATATAGAAAAAAGTAAAATTAGATAGCCAATAATGAGTAAGGGTTCTTTAACAATCACCTGTAAAGTGTTGGTAACAGAGTACTGAACAACTTGTACATCCGAAGTTATTTTAGAAATGATATCACCTTTTCTTTCATTATTAAAAAAATGGATGTGTAGGTTGGTTACCTTTTCAAATACATTTTTTCGTAGATTTTTTAAGGTATGAATTCTTAGGTTCTCTATAACTCTTTGAGAGAAATACCTAGATATATTACTTATAAAAACACAAGTAACCAATACCGCAGCAACAAATATTAAGGCTCCTTTATGGCCGTAAGTAACAGTAAACTGGTTTAAATAGAAGTTGAAAAGATGTGATAAATATTCAAAAGTAAAATCAAATTCTGGAAATTGGTTATTTTCTAAGTTTTTGGTAGGGTCTTGATTAAATAAAACATTTAAAACAGGTATAAGCAAAGAAAAAACAATTGTATTGAAAATGGCATACAAAACCGTGGAAATAGAATATGGAATTGCAAATTTGCTTAGAGGTTTTGCAAAACTTAGAATCCGAAAATAGATTTTCATAAAATTAATTAGCTAAAAATTGTATCCATTAGGAATAGTCTTGGTTTTCTCCCTAATGGTATCATAATATACAGAGAGATTTTGGCTCTCATTATTCCTTTCATTTAAATGGTGATATAAGTGAAAACATGTTGCTGCCATTTTTAATTGTCTTCTATAAACACCATTGTTTACTAGTCTGGCAGCTAGTTCTATATCTTCATGCCCCATCCTGTTAAATTATTATTATAACCATTAACAGCAATAAAGTCTTTTTTCCAGAAAGCAAAATTACAACCTCTAAGGTTATTTGTTCGTGTTTTACTTCCAAAAAATAAAAAGGCCAATTTTGGTAATCTAGTAGCGTTAATTTTTGATTTGACTACGCTACGCATCAAGGAGAAGTTTAATTCTTTTTCTTTTAAAATTTGCTGCGTAAAATTACTAGGAAGCATAGCCCTACTTCCTTTAATAAAGAAATTCTCTTTCGCAAAATGTAAATGATCTGCAATAAAATTGGGGTGTAATAACATGTCTCCATCAATTTGTATGATATAATCATGGCTAACCTCTTTAATAGCATTATTCATGATTAAGGTTTTTCTGAAACCTTTATCTTCATGCCAAACATGTTTTATGTTAAGCTTATTTTTAAAAGCATTTATAACCTCCGCTGTTTGTGGTTTTGAGCCATCATCAGCAATTACCACTTCCGTTGGTATGATGGTTTGTTGCACAATACTTGTTAAAACCAGCTCAAGTGCCTCGGGCCAATTATAGGTTGATACAAGAAGAGAACAAGTACCTAAAGCCATTGTGCTAGATGTATTGATTAATGCCTCGTTCACAAAATGCGGTTTTATTTTGAATAGCCAATTTGAAAATCTTCATATTATTTTCTAATGTTTTTTAGAATTTTCTTTATGCCATATATGATACACGATACCACCTAGTTTAAGGAATCTTTTCTTTATGCCAATATTTAATAATCTTGTGATAAATTCCTTGTCTTCTGGGCCCCATCCAAGAAATTCTTCATTATATCCATTCACTTTTATGGCATCAGCTCTCCAGTAAGCCATATTACAACCATGAATTTCATAAAGCTCATCTCCTTTCATCTTATAGTTGTATTCAAAGAAGCGCCATAAATATGGGAATCTTATTGCACTAAATTTATTGCTTACACCTTTATCTAGATAGCTAACACTTTTTAGCTCGTTATTTAATAATTTTATGGAAGTGCTTTGGTCTAAATAAATTCTACTAGCTCTAACAAATGAATTAAGCTTGGCAAAATGTAAATGGTCTTTTACAAAATTTTTATCCAGATATAAATCTCCATCAATTTGTATGATGTAATCAAAAGCTGCAACAGCAAGGGCTTTATTTCTTATCTCTGATAGTTTAAAACCTTCATCGGGTTGCCAAACGTGTTTTATTGGAATAGGGCAGTTTATCTTAAAGCTTTCAATAAGTTGCTTGGTTTCATCTTTAGATCCATCATCTGCAATGATAATCTCATTTGGCTTAATAGTTTGTTTAAATATACTTTTCAAGCAAACCGAAAGCGCATCCGGCCAATTATATGTAGAAATTATTAAAGAACACTTTGGTAAAATTTTCATAAAAAAAGAGCATTTAATAAATCCAATGTCATTGTAAATGATTAAAAGTCATTAATAGGGCTAAGTTAAATACTGTCTTAGCTATTATTTTTATAATTTAATTTTAAAAATAGTGAATAAATTCACATTTGATGATTTACTCCCTCGTGGAAGTTTATCAGCATCATCTTTACTTTATCTTATTATAGTTTTTGTATTCAAAAGGCCTATATCCGGTTCGCTCTTCTATCCATTTCAATAAACGCCTTCTAAAATTTAACTTTTTCTTTACCACTGTGGGGTCATAAGAGAATTCCCAATTGGTATTCGTAATTCTTTTCTGAATTGCTACAGGGTGACTGGCATTAAATTTTACCAACTCATCTGCATTACCATAATCAAAGCTTTCTGCTTTTGGTATATGGGTTTCAATCCATTCATCATCACGGTAAAATTTATTAAAGTTTCTTACCTTATTATTTAACCCTTGTGGCGGTTTAACCCATCCATAATGATAAATATAAGCATCAATTTCTTTTACCTTTATTTTTCTATCCTCGTATCTAAACCCTTGTGCATCTCTATAAGAATGTATGCCTTTTAGATTTTTGATGATTCTTATTTCTTTTCTGTACCAGCGTCTGGATGTAGCTATATAATCATAAGAACCGTAAAAATGTAGGTACTTAAATAGTAAGCCTTCAATGTTTTTATCAGGCAAACATAGTTGCATTTCTTTTTTATGGTTTCATGGTATTTTTCATGCACAACCTCATCACCTTGGATATAAAACGCCCAATCTGCATCTGGAGATATAGCTTCAAAAGCTTTATCTGTTTCTAATGCAAAAGTTTTACCGCCTTCTCTTAGGCTATCATCCCAAACGGTATTAATAATTTTTATTTTGGGCGATGCTATAGCTTGTAATAATTGTAAAGTATCATCGGTAGAATTACCATGAGCAATAATAAATTCATCACAAAGTGGTAAAATGGAAGTAATAGCCTCTACTATCGGATAATCATTAACTACAGCATTTCTAATAAAGGTAAAGCCAGCTACTTTCATCTTTCTGATAAAGTTTTGATTTTAATATTCGTGAATAAAAGTAACAAAAATACGATGCTAATACCACTTATCTGCCTTTCCATGCTATTATCTGTAAACATATGGAAGATAATGGGAATTATAAATGCTAATGATAGGCTGTTTCGGTTTATTTCTCTCCATAAGAGTATGAACCCAAATACGAAAATCAAAAAGCTAAAAATTACTCCATAAGAGGCTAAATAATATAAGTATTGGTTATGGACAAAAACTCTGTTTTGAGGGATTAGCCAATAAGAGTTTTGTGCGTATTGATTATCCATTTCTTGCTCTAAATCTGCAGGAGCAACACCAGTAAAAACATTTTTTTAACGATTTCTAAAGCACATTTATTAGCAGCCCAACGCTGGCTTATAGAATAGTAATTAGGATTTTTATTTTCTATTATATTATCAATATCGTTTTTTGTGAAGATAACTTTTTGTTTAATGGCAGGCACTTTTTGATAAATTACTATCAACGCTAAAAACAATATTAAAAAGTAACCTATATATCTATGGTTCTTGGTTTTAATAGCTTGTCTGCAAACAAGAATTAGCGCTATCATAAGTAAGCAACTTATAGTAAAACGTTGAGCCACTACAATTAATCCGATAGCTAATAAGCATAAACAAGCTATCATTAACCATTTTTTATATAATTTAGATGGATTTAGAAGTGATATCCATAAAGCTATAAACGCAATGCTATAGAGTAAGCTAAGTTCTGTATGGTAGGGGCCCAACACAGAACGTATATTTCCACCTCTTGCGATAATTTCTTTATAAAGTGGCTGATGAGATAATACCCACCCTAAATCTACACTGATGCACAGAACTCCACAAAGGCCAAAAAATAAAACTAAACGTCTAATTGTTGCCTCTTGCGGTGTTTTAGCGAAAGTAAAAACTAAGGGCAATAGCCATAAAAAGCTATTTTTAAAAAGGATGTCTAACCACAAGGCTTTATCGCTGGTATTCCAAAAACTTAAACAAATTAAAATATATAGTCCTATAAAAAAGTAATGCTTTAGCTTTATAGGGTTTGGTTTTTGATGTTGATAAAAGTTGAATATGGCAATCAAAAGCATCAAAACAAGAGAAATAGATAAAACCGCTCTAGAAAAAAACAATCCAAAGATGAGTAAAAAACAAGTTGCCTCTAAAGCATGTTCTTTTAATAAAGAATAAATGCTTGCTTTAGCCATCTTGCTCATTTTAAATTGATATTTTTACTTGAAACACGACCAAAGTTAAACTAATGTTAGACAAGGCAAAAAAACTATTAGCAAGTATTCATTCTGGAGATGTTAAATCTCTTGCCAGAGCTTTAACTATCGTAGAAAATGATTTAGCTGGGGCTGATGATATTTTGAAATCTTTACATCCACAACAAACTCCGGTTATTGGCGTAACAGGTCCGCCGGGGGCTGGTAAAAGCACTTTATTAAATAGTTTGCTTGGTAATTTAGCAAAAAAAGGTAAAAGGATAGCAATTTTAGCGGTAGACCCCACTTCGCCATTTAGTTTTGGTTCTTTGTTAGGAGACCGTATACGGATGAAAGATCAATTCAATCATCCAAATATTTTTATACGTTCTTTAGCTACCAGAGGTGCTTTAGGAGGCTTGTCTGGCAAAACAATAGAAATGACTGATGTTTTAAAAGCGGCTCATTTCGATTTTATTTTTGTAGAAACCGTTGGTGTTGGGCAGTCTGAAGTTGAAATTGCTGGCCTGGCAGATTTAACTATGGTAGTTCTGGTTCCAGAATCTGGTGATGAAATACAGCATATCAAATCGGGCTTAATGGAAATTGCTGATGTTTTTATCGTCAATAAATCAGACAGGCCAGACGCTCAATTATTTACTATAGGACTTAACAAATTAATTAGGGAAAAGCATCAGCAAATAAAAGTTTTCAATACCGTAGCCGATAAGGGGACAGGCGTTTTAGAGCTTGCCGATGAAATTTTGGCTTTTAAACCTCATGCTGGGCTTAAGAAAATAGAATTGCTTACCCAGAAAGCTTGGCAGCTGATTCAGCATTACAGAATGAGAGATATTCAAAAAAATAAGCTTCAGCAAAAAATTACCGAAGCTTATCATCCTCATTTTAATATTTATCAGTTTATAGAAACTTTTATGCGTTCATCATAGCTTCTATTTCTTCTGCTTCTATGGGGATATGCGCCATTAAATCTACTGGGCCGTTTGCAGTTACTAAAATATCGTTCTCTAGCCTGATGCCTAAATTTTCTTCCAAAATATAAATTCCTGGTTCGCAGGTTAAAATATTACCAGCTTCAAATGGCTTATACCTGTCAGAAATATCATGAACATCTAAACCTAAATGATGCGATGTGCCATGCATGAAATATTTTTTGTAGGCCGGTACAGCCGGATTTTGTTTAGCCACATCATGTTTGTCTAGTAAACCAAGCTTTATCAATTCGTTGGTCATAATTTTACCTACCTCTTCATGATATTCGTTCCAAATGGTGCCAGGTACCAACATCTTTTTTGCTTCTTTAAAAACATGTAAAACAGCATTATAAACATCTTTTTGGCGTTTGGTAAAACGGCCGTTAACCGGAATAGATCTGCTTAAATCTGCATTATAGTTGGCGTATTCTGCTGCAAAGTCAAATAATATAACATCACCATCTTTACAAGGTTGGTTATTATCATTATAATGAAGGATACAAGCATTTCTTCCGGAAGCTATAATAGGCTCGTAAGCATGGCCTGTTGCGCCTTGCTTGATAAACTCATGAATAATTTCTGCCTCAATCTCATACTCCATTACTCCCGGCTTAACAAATTTTAATACCCTGTTAAAGGCATCTCCGGTAATGTTACATGCTTTTTGTGTGATAGTAATTTCTGTATCAGATTTTACCATCCTTAAATTGCGCATAATAGGCGCAACACGTTGGTAATGATGTAAAGGATATTTCGATTTTAAATCCTCAATAAACCTCAAATCACGATAAGGTACATGATTTGCGTAACGATCATTCTCATTAGTATTGAGGTAAATATGGTCTGCATAATGGATAATGGCCGATAAAATATTCCAAAAATCATCTAACCAATAAATGTTTTTAATGCCAGAAACACGTTGAGCTTCTTCTTTTGTATACTTATGGCCTTCCCAAATAGCGATATGCTCATTTGTTTGTCTTAAAAAAAGGACTTCTTTGTACAAAGGATTAGGACAATCTGGAAAAAGTAACAAAATTGTTTGCTCTTGGTCTATTCCAGATAGGTAGTATAAGTCTGGATTCTGCTTAAATTTATATAATTGATCCCCACTTCTGGTATATTCGTCGTTTGAATTAAAAATGGCTAAGCTGCTTTTTTTTAGTTGCTTAGCTAGATTATTGCGGTTTAAAACAAATAAATCCGCGTTTTCTGTAATGTATTTCATGAAACTAATTTAAGAAACCCTATTTTAAATCGTCCGTATAAACTTTAGATATTAAAAAATATTTTGGAATGAAGTTTGATAAGTTGCTCATGTCAAACTTAAAATTTATTTTTACGACAAATTACAATTAAAATTGTTTAACCTTTAAAAAAAATGATTATGAATTATTCTACATTGAAGAAAACGGTCGCTTTATCATTAGCAACTGCTTTCGCTGTAGCGGCACATGCGCAGGTTACTCCTGCTACTACGTCGTCGTCTGCAAAAACTTTCGGAGGGAGAGGCCAGTACAGAACTTGGACTTTTGGTGTTAACGCTGGTGGTTCTTTACCTTTAAGCATTATTGGCGGTACTAATGATTTCGGTAAAAACGTTGAATTCGGTGAGCATACTATGGGTTTTTACTATGGTATCTCTGTAAGAAAGCAATTAGCGCACTCTTTTGGCTTACAAGGTAACTTAAGCAGAGGTAATGTTATTGCTTATAACAAAGGTGTTGGTACTTTCATACCAGGTGATGCAAGAGCATTTAGTACTGCAAAAACAGAAGTACAATACGATATTAATTTAAGTGGAGTTGTTAACGTAGCAACAGTAGATTTCTTAAGAAGAGAGAATGCAGTTAATTTCTACGTTTCTGCTGGTTACGGTTTAATCGCTTTTAACCCAACTTTATATACTACTTACGCTGGTGGCGATGGTACTCCTGCAGTAAACAACAAAGGTTTATATGGTGATGAAGGTTCTAATGACTACATCAGACAAGCTTACATTCCTGTAGGTGCTGGTGTTAAATTCAAACTATCTGACCGTGTTGCTTTAGATTTTGGTTATGATACTAAATTTATTGATGGAGATAACTTTGACGGTGTTTATGCTGGTGGTACTTCAAAAGATAAATTCTCTGTTGTACGTGGTGGTTTAGAATTCTCTTTAGGTTCTAAAGCTAAACCAGATTTAAACTGGGTTAATCCAATTGCAATGATGTATGATGAATTGAAAGATCCTACATTACGTCAAGAAGTTGAAGCTTTAAAAGGTCGTGTTACTAACGTTGAGCAATCTGTTCAAGATCTTAAAAAAGATTCTGATGGTGACGGTGTTGCTGATCACTTAGACAAATGCCCTAACACACCTGCTGGTGCTAAAGTTGATGGTGCTGGTTGCGAGTTAGATACTGACGGTGACGGTGTGCCAGATTGGAAAGATGATTGTCCTACTGAAAAAGGTACTGCAGAATTAAACGGTTGTCCTGAAATGGGTTCAGCTACTATGTCTGGTGTTGATAATATTCAATTCGAGTATAACTCATCAGTTTTAAGAACTTCTGCTTACCCTACATTAGATAAAATCTCTTCTGCTTTAAGAGCTAATAAAACTCAAGGTCTTCAATTAGATGGTCACGCTTCTGAAGAAGGTACTGATGCTTATAACATGCAATTATCTGTTGATAGAGCTAATGCAGTTAAAACTTATTTAGTTAACTCTGGTGTAGATGCAAAAAGAATTTCTACAAAAGGTTACGGTGAAAGCCGCCCTATTGCATCTAATGCAACTGAAGAAGGACGTGTTAAAAACCGTCGTGTTGAATTCAGACAGAAATAATTAAAACAAATTTTAAGAAAAGGGAGTTCTTGCAAAAGGACTCCCTTTTTTATTTTATAAATTTGTATTATGTTATATTTCTTTAGAAAGAAAGACCCTAACAGGCCAGATAATTTTAATCTGAGAGTTATGCACTGGATAAACAAAACAGCTATCATTGTTTTTTTATTAGGCTTAATTTGGAAACTGTTAGATTGGTTTGTTTTGCATTAAGAGACAACCATTTAAAATTTAAATAATGAAAAAAATCATCAATACGCCTTTGGCGCCAGCGCCAATAGGCCCTTATAGTCAGGCTGTATTAGCTGGCAATACCTTATATGTTTCTGGTCAGATAGCCCTACATCCAGATAGTGGTCAAATTATAGACGGTACTTTAGAGTTAGAAACCAAACAAGTAATGTCTAACCTGAAGGCGGTTTTAGAAGCAGCAGAGATGGATTTTAGCCATGTAGTAAAACCTCTATTTTTTTAAGTGATATGTCTTATTTTGCTCAAGTAAATGAAATTTACGGGCAATATTTTACTGGAAATTACCCGGCAAGAGAAACTGTGGCGGTTAAAACATTACCTAAAAATGTTAATGTAGAAATATCTGTTATTGCCGTTAAAGCTTAATGAGCTTAAAATTAAAATGTTTTTTAGCGGCATTATCTGCAAATATTATTTGGGGTTTTGTAGCTGTTCCAATAAGGTTTGTACAGAACTACGAGGCAGAGCAAATACTTTTTTGTAGAATTATAGCTTCTTTAATTATCTGCTGGTTATTTATTGCTTGTTTCCAGAGAAAGCAGTTAAGGGTTGATATCAATACCTTAACATCAGCTCCAAAAAAAGAAAGAAAAACCTTAATTCTCTTATTGCTTACCTCTGGTGTTTTAATCACTTTTAATTGGTACGCTTTCATTTATGTTATCAATCATGTGAGCCTTAACTCTGCAGCTTTTGCTTACATGATTTGCCCTTTGATAACAGCTTTATCTGGCTTTATGATTTTAAAAGAGGATATCAATAACCAAAAAATTGTAGGAATTATGATAGCACTTATAAGTGTGCTTATTCTTGCAACGGGCTCATTACATGAAGTTCTATGGTCTATCATCACCGCAAGTTTTTATGCATTTTATTTAATTGTACAAAGGGTTATCAAAGCATTTAATAAGATTAATATGCTGGGTTTGCAATTAATTATTGCTTTTATAGTGATTTTACCTTTATACCTCAATTTAGGATTAAGCCTTCCTACTAACTTAAACTTTTGGTTTGATATTATCATTATAGCCGTTTTATTTACTTTGATACCTCTATTTTTAAGTTTATTTGCTTTAGGCGGTTTACCTTCTTCTACGGTTGGGATTATTATATATATTAATCCGGTTATTGCATTTGGTGTAGCATTTTTATATTTTCATGAGGGTATTACTTTAATTCAGGGATTTGCATATTTATTACTAGTAATTGCAGTCATCATATTTAATTGGAAAATATTATCGGGTACAATACGTAAATTAGCGACAAGAGAAGCTACAGATTTTGAATGATCAATTATTTAAAACTCCTATAGAGTATCTAAAAGGTGTTGGTCCGCAAAGGGCAGAAATTCTTAAAAAGGAAGCAGCAATTTTCAAATATGAAGATTTACTATCCTATTATCCTTTTAGATATATTGATAGAACGCAGTTTTATAAAGTAGCAGAAGCAACCCCAGATTTAGCACATGTTCAAATATTAGTAAGGCTAAAGTCTTTTGAGGTCATCGGCGAAAAGCAAAGTAAAAGATTAATAGCCAAAGCTTATGATGATAGTGCCGAGATAGAATTGGTATGGTTTCAAGGAATTAGATGGGTAGAGAAAAACCTGAAATTAAATCAGGTTTATATCATTTTCGGGAAACTCAATCATTTCAATGGTAAAGCGCAAATGGCTCATCCAGAAATGGAGCTTTTTTCTAAGGAAAATGTAACCAAGGGCAATTTAAGCTTACAGCCTGTTTATTCATCAACAGAAAAGTTAAAACAATTTTCATTAGACACGAAGGGCATACAAAAGCTAACGGCTAATGTGTTAGAGCAATTGGCCGATAAAATAGAGGATGTTTTACCGCATTACATCCTACAGAAATACAAATTAAACTCACACAAAGAAGCTTTACTACACATACATTTCCCTACTGATAGCAAATCTTTAAAAAGAGCCCAAACAACCTTAAAATTTGAAGAGCTATTCTTTATTCAGCTAAAAATGTTGAGGAGTAAGCTATTAAGAACCTATAAGTTTAAAGGTAACGTGTTTAGCCAAGTTGGCGATAAGTTCAATTATTTTTACGAGAACCTATTACCATTTTCTTTAACTAATGCACAAAAGAGAGTGATTAAAGAGATAAGATCTGATACCCAAAAAGGTATTCAGATGAATAGATTGGTGCAAGGCGATGTTGGTTCTGGTAAAACAGTAGTTGCTTTAATGAGCATGCTTTTAGCTATTGATAATGGCTATCAAGCTTGTTTAATGGCGCCAACAGAAATTTTAGCAACGCAGCACTACCACTCTTTAAAAGCCTTGTTAAAGGATGATTTTGTAGAAATAGCTTTATTAACAGGCTCAACTAAAAAGAAAGAGCGTAAAGTACTTTTTGAAAAGTTAGCCAGCGGAGATTTAGCTATTTTAATTGGTACGCATGCTTTAATAGAGGATACCGTACAGTTCAAAAATTTAGGATTGGTTGTGATAGATGAGCAGCATCGTTTTGGTGTAGAGCAAAGAGCTAAACTCTGGCGTAAAAATGTGATACCGCCTCACGTTTTGGTAATGACAGCTACACCCATACCTCGTACCCTAGCCATGACTTTGTATGGAGATTTAGATGTATCCATGATTGATGAGTTACCTGCGGGTAGAAAACCTATAGAAACCATTCATCTCTATGAAACACAACGCCTGAGAATGTTTGGCTTGATGAAGCGAGAAATTGCCCTAGGCAGGCAAGTGTATATGGTTTATCCGCTTATTCAGGAAAGTGCTAAACTAGATTTAAAAAATTTAATGGATGGTTTAGAGGTAATGGCCAGAGAGTTTCCATTGCCACAATATAAATTTAGCGTTGTGCATGGGCAATTAACTGCAAAGGATAAAGAATATGAAATGCAGCGCTTTGTAAAGGGAGAAACCCAAATTATGGTAGCTACTACAGTTATTGAAGTTGGGGTAAATGTGCCTAATGCTTCTGTCATGATTATTGAAAATGCGGAGCGCTTTGGATTATCACAACTGCATCAATTAAGAGGAAGAGTGGGAAGAGGGGCAGAACAATCTTACTGTGTGTTGATGTCTGGCGTAAAACTAAGTAAAGAGGCAAAAATAAGATTAGAGACTATGGTAAGAACCAATGATGGTTTTGAAATCTCAGAAATTGATTTACAATTACGTGGTCCGGGAGATATAGAAGGAACTCAACAAAGTGGTATTTTAGACCTTAAATTGGCTGATATTTCTCAAGATCAACAAATACTGCAAGAAGCTAGAAAAACAGTGATAGAAATTTTTGAGGAAGACCCAGACTTAAATTTAGAAAAACATCAGACCTTAAAAAAGTTCTTCTCTGTAAAGAGAAACGGAATCTCATTAGATAAAATATCTTAAAATTATAAATAGACAACATTGGCAGCTACTTCAAACGACCCCTACATAGCACTAAAATTTCCAGAATTTAGGTATTTCTTAGGGATGAGATTTTTCTTTACCATAGGTTATCAGATACAAGCCGTAGTATTGGGTTGGTATGTTTATAATATTACCAAAGACCCGCTTTCCTTGGGTTTAATAGGTTTAGCAGAAGCTATTCCTTCTATTGGCATTGCTTTATATGGCGGTTATGTGGCAGACAAATCAGACAAAGCGGTTTTAATAAAATGGGTGGTTGGTTTAATGGTTTTAGCGTCTTTTGCTTTATATGTTGTAACCACACCCAGTATTGTTGCATTATTAGGAACCTCCAAAGTTATTACTGCTATTTACAGTATCATTTTTATAGTTGGTATTGCAAGAGGTTTCTTCTCGCCAGCAGCTTTTTCTTTAATGGCGCAAATTATACCACGAGAGCATTATCCAAATTCTTCTACCTGGAATAGCTCTATTTGGCAAATTGCAGCTATTGTAGGGCCTGCTTTGGGAGGTTTATTATACGGCTTTATAGGTGTGCATACTACCTTATTAATTATTGTTGCAAGTATTTCTATTTCTTTTTTTGGCACCTTTTTCTTTAAAAGTGTACCGCCTACTTATGTACGTAAAACCAGTATTTACGAAAGTTTATCAGAAGGTTTAAAGTTTGTTTTTAAAACCAAAATGCTTGTTGGCGCCTTAAGTTTAGATTTGTTTTCGGTGTTTTTTGGTGGTGCTGTAGCTTTAATTCCGGTAATTGCAAGCGAGGTTTTAAAAGTAGGCGCTCAAGAGTTTGGCATGATGAGGGCTGCACCCGCTTTAGGCGCTGTTTTAACCATGTTAATGATGACCCGTTTCTCTCCCATGGGCAAACCTTGGCGCAATCTTTTGTTTGCTGTAGCTGGTTTTGGAATATCAATTATAGGCTATGGTTTATCAAGAAATTTATACCTCACGCTTTTCTTTTTGTTTTTAGAAGGCGCTTTTGATAGTGTAAGCGTCATTATTCGCTCTACCATTTTACAATTGCTTACGCCTGATGAAATGCGAGGCAGGGTATCAGCGGTTAATGCCATGTTTATAGGCTCTTCAAATGAGATTGGTCAGTTTGAATCTGGTTTAACAGCAAAATTGATGGGCACTGTACCAGCCGTTTTATTTGGTGGGAGCATGACTTTAGTAGTAGCGGCTGTTACCTGGATGAAGACTCAAAAACTTATTCCCAAAACTTTACATGATATTAGCAAGGGTGAAGAAAATTTGTAATAAAATCATCCAACATCTATCTTATTAAATAAATATATGAGAATAGCTTTACTAATTTCTTTTTTACTTCTTTCTGGACTTGTGTCTGCACAAAGCATAACCATAAAAGGTAGAGTTAGTGATGGGCAAGGAGCCCCTATTCCCTTTGCTACTGTTTACCTTAAAAATTCTACCGTAGGTACATCAGCCAATAGTGAAGGCGAATATGCGCTAAAATTAACAACAGGTAAAAAGGAAATTATTTTTAGGGCAGTGGGCTATAAGCTGCTTGAAAAGTCTTTAGAACTATCTACCAACTTAAATCTCAATATTACCTTAGAAAGCGAAATTTATCAATTAAAAGATGTTGTGGTAAAAGCTGGTGGTGAAGACCCTGCTTATGCTATCATCAGAAAAGCCATCAAAGAAAGAAAAAAGCATCTTAAAGAAAATGATGCCTATACAGCAGAAGTTTATATTAAAGGCTTGCAAAAATTACTAAAAGCACCTAAAAAGTTTTTAGGTAGAGATATTGATAAACTAGCAAAGCAGGCAGGACTAGATTCTAACAGAACGGGAATAGTTTACCTCTCAGAATCGCAATCTAAACTTAGCTATAAAGCCCCTGAATATAAAGAGGAAATGCTATCCTCTAAGGTATCTGGCAGTAACCGAGCCTTCAGCTTTAACCGGGCTAGCGATATGAATATTAATTTCTATGAGAACTTACAAAGCCTGGGCGATTTAAGTAATAGACCATTTATTTCTCCTATCGCAGATAATGCACTTTTTTATTATGATTACAAATTGCTTGGTTCTTCATTTGAAAATGGCCAGGAAATAAACAAAATTCAATTGATACCTAAAAGAGGCTATGACCCAGCTTTTAAAGGTTATATCTACATTATAGAAAACAGTTGGCGCATTTATAGTTTAGATGTTTTGATGACTAAAGAGTCGAACATTAAAATTTTAGATAGCTTAAAAATTAGTCAGCAATACTATACTGTAAATAAAAATAAATGGATGCCTGCTTCTGTAAAATACGAGTTTACAGGCGGTTTATTAGGTTTTAGATTTGGTGGATATTTTATAGCTCTTTATAGTAATTATAATTTGAACCCCAATTTCAAAGAAAAGGAGTTTAAAGAAGTACTAAAAATCACGAAAGAAGTTAATCAAAAAGACACCAGCTATTGGGCTCAGGTACGCCCGGTTCCGCTTACTGTGGATGAAGAAAAAGATTATCAGAAAAAGGATAGCTTGGCAAGAAAAAGAGAATCAAAACCTTATTTAGATTCTTTAGACAGCGTAAACAATAAATTTAAATGGAAATCCTTTTTATTGATGGGAGGCTATAACCCACGCAATCGTTTTAAGAACGAATTTTATAGCTTCAATTCTCTGCTAGGTTCTTTTTCATACAATACGGTAGAAGGTTTTGTGATGAATTATGAGGCAGGCTACAGAAAGAAAATTGATACCCTAAATAACCGTTACCTTGGCGTAAGTGGTAAATTGCGTTATGGGTTTTCTAACAAGCTTTTTAATGCTAGTATGAAAGCCAATATTCCTGTTCTTACCAGTGCTACTTTAGCTCTAGGCTTAGGGTCTGATGTAGTTGACTTAAACAACCGCGGTTCTGTTAAACCTTTGTATAATAGCATCAGTAGTTTGTTTTACGAGCGTAACCTCTCTAAATTTTATCAAAAAAGATTTGTTAATGCCAGTTTATCAGGAAGAATTATAGGTGGTTTAAGAGGGCAGGTTTATAGCGAATGGGCTAATAAAAAATGGCTGCCTAATACTTCTTCATATACCATTATAGATAAGGATAACCGAGATTTTACCTCTAATAATCCTTTTATGCCTTTGGCAGATGTGCCCTTATTTCCTGCATATCAATCATTGAAAATTGGTTTAGGCTTATCTTATAACTTTAGTAATAAATACGTAAGCTATCCTAGTGGCAGGTATTATAATCAAACTCTATATCCAACTTTAGCGCTTAACTACACTAAAGGTATGAAGGGTGTTTTTGCCTCCGATGTTGATTATGATTTAATAGAGCTAAGTTTATCCAAAAACGATGTAAAAACCGGCTTCTACGGCAGCTTTAATTTTTATATTGGAGCCGGTAAGTTTATCAATAATAGGGCTGTTTTTTACCCAGATCTAAAGCACTTTAGAGGAAACCAAATTAGAGTTTTTGAAGAAACTGGAAATACTTTTATGTTCTTAGACTATTACACTCATAGTACATCAAACCAATATATAGAAGGGCATTTTGAGCATAATTTTTCTGGATTTTTTACCAACAAAATTCCGCTCATTAGAAAGCTGAGGTTAAAAGAGCTTATAGGTGTTAATTATCTAACCACCTCAACATTACAAAATTATCATGAGCTATTTGTTGGCCTACAATATTTGAATATTAAGGCTTATGTGGGTAAATCTTTTATTGGCAATCGAGAATCACAATCTGGTTTGAGATTAGCTATCGGTTTATAAAACCAACGCTTAAGCTAATGGCATAAAAGACCCTTAAAATTTCTTACGAGCAGCAACAGGCTTAGCCCAAAAGAAATAAATGATAGCGCCAAGAAGTGGTATCAGAATTACAATTAATAACCAAACCAATTTGAGGTTGGCAGACAAGTTCTCGTTAAAGAAAATATCTTTAGCGGTTACCAAAGCCACCAATAAAGGGAAAAAGAACAAACCAGCAAGCAGCATAAAATAGCCGGTTTGTGATAGTTGTAATAATACAGATAACATCATGAGCTATATTTTAGTCATCAATACACAAAATTAAACAAAAGCTTTATCGTTTAGCCTTTTTTCGCCAATTTGTTGTCTCCACATGGCATAGTACAAGCCTTTTTCAGCTAATAAATGTTCATGTTTACCAACCTCAACAATATGGCCACGCTCTAAAACAAAAATCCTATCGGCATGCATAATGGTTGATAAACGGTGGGCAATTAAAATGGTTATTCTTTCCTTTCCTCCAGATACATCTCTGATGGTTTCTGTAATCTCTTCTTCTGTAATGGAGTCTAGCGCTGATGTTGCCTCATCAAAAACTAAAATATCTGGCTGTCTTAAAAGCGCTCTGGCGATAGATAATCTTTGCTTCTCGCCACCAGAAACTTTAACACCACCTTCGCCAATAACGGTATTTAAACCAGCATCGGCCCTAGCCAATAAAGACTGGCAAGCAGCTTTTTGTAAAACCTGCATACAAGCTTCATCCGTTGCGTTTGGACTCACAAAAAGTAAATTCTCTCTTATAGTACCAGAAAAAAGCTGAGTATCTTGAGTTACAAAACCAATACGCTCTCGCAGCTCATCCAAATCTATTTCATTACTATGGATGCCGTTATAATTTACCTCGCCTTCTTGTGGCTGGTATAGCCCAACCAGTAATTTTACCAAAGTAGTTTTACCAGAGCCAGAAGGGCCAACAAATGCAATAGTTTCTCCTTTTTTTACGCTAAAGCTGATGTTGTGCAAAGCCGGAGCCAAGGCGGTTAAATGCTGAAAGCTTAAATTTTTAAGCTCTAACTCATGAATTGGGCCGGTATGTTTCGGGTGCAAAGGTTTAACCTCTTTTGGTGTGTTTAAGGTTTTTTGGAAATTATTTAAGGATGCTTCTGCCTCCCTATAAGTTAAAATGATATTACCAAACTCTTGTAATGGGCCAAATAAGAAGAAAGAGTAAAACAAAAATGTAAAGTACTGCCCTGCCGATATATCATTTTTAAAGATGAGCAAGAGTAAAATTACCACCATACTGCTTCTAACGAGGTTTACGGTTGTGCCTTGTAAAAAGCTCATGCTACGTACATATTTTACTTTTTTAAGCTCAAGGTCTAGAATTTTATAAGTGGTATTGTTTAATCTGTTAATCTCTTGGTTGGCTAAACCTAAGCTTTTAACCAGTTCTATATTTCTTAAAGATTCTGTTGTAGCGCCAGCCAAAGAGGTAGTAGCACCAACAATTTTCTTCTGTATGGTTTTTATTTTTTTACTCAAAAACCAACTCACTACAAATATTAAAGGTATAGAAGCAAAATAAACTAGCGTAACTTTATAGCTTACAGTTAAAGAGTAAATAATCACAAAAACCATCCCTACCAAACTTGTAAATAAGATATTGATAAAAGCGATGATAAACTTTTCAGAATCTGTACGCACTTTTTGTAAGATACCTAAGGTTTCTCCGCTACGTTGGTCTTCAAAAGTTTGATAAGGTAATTGTAGTGAGTGTGCTAAGCCATCAGCATACATTTTAGCACCCAATTTCTGGGTAATGATGTTAGCAAAATAATCCTGAAAGTTTTTAGCAATACGAGATACCATAGCCGCACCAACAGCCAAACCTACCAGTTTTAAAACACCTAAAGTGAATTCAGACTCTGTTAAATCATCCTTTTTATTGATGAAATTATCTACAATTTTACCAGTAATATGAGGGTCTATTAAAGAGAAACATTGGTTAATAGCGGCAAATAATAGTGCTAAACCTATTAAACCTTTATATCCTTTTAAATACTGAATAAGAATTTTCATGAAACAACGCTACAATACTTCGCAAATATAGAATTGATTCATGGCTAATGTCTCATTTGCCAGTAATATTTAAAAGCGTTTAACTGACATTTATTTGTAGCGTAAAAGTTACAGCTATTATTTAAAGGTGTTTAAACTTAAATCAAAAAAAATAGTCCTTATTTTGCACAAACTCACCTAAACGTATAAATGAAAAAATTTTTCATCAGTATTGCATTTACCTTAATTTGCTTACAAGCCTTAGCACAAAGGCAGCCTTTAACAGTCTCGGGCCAGTTAAAAGATTCAACAGGAGTTACTGTCATTGGGGCTTCTGTAAAATTGGTATCAACTTTAGATACGGTTTTAACTACATCAGATTTAGACGGAAATTTCACCTTCAGAAACATTAAATCTCCGGTTTTTACGCTTTCTATTTCAGCTTTAGGTTATAAAGCTATGACCAAGAGTTATACTTTAGAACGCCAAAGAGGGCAACAAGTATTAACATTGGGCAATATCATATTAGCAACCGATAGCAGACAGCTGGGCGAAATAGTAGTTGATGGTACGCCTGATGTATTGGTTAAAGAAGATACCTTACAATATAAAGCAGACAGATATAAGCTAAAAGAAAACGCCTTAGCAGAAGATTTATTAAAGAAATTGCCTGGTGTAGAGGTTGATAGAGAAGGTAATGTTACCGCACAAGGTAAAGCTATTACCAGAGTACGCGTAAACGGAAAAGATTTTTTTGGTGGCGATGTTAAAACCGCAACACAACAAATTCCGGCAGATTTACTAGAAAACGTCCAGGTTATTGATGATTATGGCGATAGAGCTAACCTAACAGGGGTAAGGGATGGCGAGCCAGAAAGAATCTTAAATTTCACCATAAGACCCGATAGAAATAAAGGTTATATCACCAGAGGAACCGTAGGTGCAGGTAATTTAGATCGTTACCAAGCATCGGTTTTTGCTGCTAATTTTAATAATGCCAGACAAATATCAGCGTTAGCAAATTTAAATAATACCAATGCAAATATTTTCAGTTTAACGCAAGGTACTGGCGGTGGCGGTGGTAGAGGCGGTCGTGGTGGTTTTGGCGGCGGCAATGCAGATGGTTTAACCAACATTAGATCATTAGGTTTAAACTTTCGTGATGAGTGGAGCAAGAAAGTAACCGCTTATGGTAGCTACAGTATTGCTTCTAGAGATAACAATACTTTTAATAGGTCTTTTCAACAGATACTTGATGCCAATACAGTAGTACAAAACTTGGATTCTGGCAATGTAGATAATGGCAACCTAAGTCATAGGTTTGATTTTAATATCGAGTATAAAATAGATTCTTTAAACTATTTAAAAATTACGCCAAGGTTTAGCTATGCAACAGGCGATGAGGTAGATATCTCAACATTCTCTATCAATAATGACAATAATCTTTTCTCTAACGGTCGTATCAATGATTTTAGCGATTCAAGATCTCCTAATTTTAGTACTGCTATTTTATTTAATCATAGGTTTAGAAAGGCTCAAAGAAATTTGGCTTTAACCGCAGATATTAGCACCAACTCAAACTTAAGAAATCAAGAAACAGAGAATTTTAATTTTTTGGCAGCTAATCCAAATGATTTAGAATATCAGCGACAGCTTATAGAAAATGATAATGGAAATGATAACCTAAGATTGGGCTTTTCTTATAACGAGCCTTTATCTAAAACAGCAGGTTTAGAGTTCAATTATGAATACAACTATAACAACATAAAAAATAACAGAACGGTATTATCTACCCAAATACAAAATGCAACACCTTTAGTTGATGAAGATTTAAGTAACGAATACGAATTTCAGTTTGTTACCAACAGGTTTGGGCTAAATTATCGGGTAAGACAGGCTAAGTACAACTATTCTATAGGAATGGGTGTGCAGCCATCAGTTTTAACAGGTAATGCCATTACTTTAGACACTACCTTTAAAACTAAAGTGGTAAATATTTTCCCTACCGGAAGGTTTAACTATAAATTCTCTAGAACAAAAGAGCTTACCGTAAGCTATAGTGGCAGAAGTAACCAGCCTAGTTATAATCAATTACAACCAGTAACAGATAATTCAAATCCGCAATTTCCGGTAAAGGGTAATCCAGAGTTGGAGGCCGAGTTTAACAATAGTTTCAATATTAGGTTCAATAATTTTAATGCAGAGTCTGGCAGAACATTCTTTACAAATATTTCTTACAATTTTACTCAAGACAAAATTGTAACCAATACCGTTAGGATACAGAATTCTGCTATTGGGGCTTTGCAAGAAAGACAGTATTTAAATGCTAATGGTTTTTATGCAATAAATGGCTTTTATTTCTTCTCTAAAGCATTTAACGAGAAAAAATATACCTTAGGTTTAAGAGGGTCTGCTAATTATAATAATCAGGTTTCTTTTATCAATAGCCAAAGAAATATTGCAAGAAACACGGTTTTAAGTCAGCGTTTACAACTGCAAATACAACCAAAAGAGTGGTTAGAAATTGTACCAGCAGCAAGTTTTAGCTACAACCTTAATGATAATACCCTGAATGAAAGAGCAAATGCAAAAGTTAACACTTGGAGCTTTAGCTTTGATAGCAAGATTTATTTCACCAAAACATTTTTAATAGGTACACAGGCTGATAAAAACCTAAATAGCGGCTTTAATAGTGTTAGCGTAAATCCTTTCATCATTAACGCTTATCTAGAAAAACAATTCTTTAAAGGCAAAACAGGTGCGCTCAGGTTATCAGCATTTGATTTATTAGATGAAAACGTTGGTGTTAGCAATACTGTAAATGAAAACATTCGGGTAGAAAGAGAAAGCAACCGTTTGGCACAATATTTCATGCTTACGTTCACCATGCGTATCAATAAATTTGCTGGAAGAAATAATTTAGAACCCGAAATGGGAGAAGGACAAAGAAGATGGAGAGGGCCAAGTAATTAAAAGGCCAGGTTTTATAAAAGCAAAAGAGGTCTGATTTTTAAAAATCAGACCTCTTTTTTTTCTTAAAGCCTATTGTTTTCTATATTAATTAAACCTTTTTTAAGGGTAAAAACCACATATTCCCTATTTCTATGTAGTCTTTCTTGCAGATGATTGATGAGGTCATCCTCTTTACCAGGTGCAAAAACAAGGTCATCATCTGTTAAATGATTATATTTTCTTTTTAGCTTTATTTTTAGCCTATCCCAATCTTTTATAGCTATTGTAATCTCTGCCATGGTTTTATATTTGATACAAAAATAGAATAATGTACTTAATTGTAAAGGGATTTCCCTATCATTATTTATTATTAGAAACAATAATTTGGTCCAATTTGTGTTAATGTTAAGAACAAATTAAAAAATGAACATGAAAAAAATACTATTCTTGAGCTTATTTGCCATGTTGTGCGCAAGTAGTTCATTTGCTCAGTTTAATTTAGGGATAAAAGGGGGCTTAAATTACTCCACTATTAAAGCAGAAGATCAACAATTTGATGAGTCTGGAATTCTAGGGTATCAATTAGGTTTATGGTCTAGAATTGGTGGTAATTTCTACTTACAACCAGAACTTTACATAGGCTCTAAAGGTGCCGATTTTAAATTCCAAACCGCAGGAAGTACTGTAGTACAAAGTGGCGAAGCCAGATTTACAACTTTAGATGTTCCTTTATTATTAGGGGCTAAAATAGGTGGCGATAAACTGAACTTTAGGTTGATGGCGGGGCCAGCTTTTCAGTTTAATTTAAACACAGATGACGATGCTTTCTCACAAGCCATTAACCCAGATTTTTATAGATACAGAGATTTTGTAACCAACCTACAAGCTGGTGCTGGTGTTGATATTGGAAACCTATCGGTTGATTTAAGATACGAAACCAGCTTGCAAGACATCAATAAAAATGACGGATTAAGCCAAAGTTTATTACACCTAAGCTTAGGGTTCAAGATTTTTTAATTATAAATGATAAGACTTAAAAAGCCGATTTTGGAACCAAAATCGGCTTTTTCTATTCCGGAAAGCTCAGTTTTCCCATACTAATTTTGGGTAACTTTTCTTGATTTGGGAAGTCATAGTCATCAGGCTGGCCACACAAAGTTTCATTAGCCAATAAAGCAAATAATAAAGCCTCTTTAGCATCGGGGTTTACACCCAAAATCTCTTGCATGCTTATAAAAGTAATACCCGGCAAATGATGCATTAAGCGTTCTACCAAAAGTGGATTATGCATGCCGCCGCCACTCATCAACATTTCTATTTTTCCGCTTACGCTGATGTTCTCCTGAATAGCTTTAGCAATACCTAAGGCGGTAAATTCGCATAAGGTTGCCAAAACATCTTCTTCTTTTAAATGGATGGTATTACTTTTTTGTTGCGCCTCATTTAAATACACCAAATTAAAATGCTCTGGTCCGGTGCTTTTTGGAATGGGTGTTGTAAAAAAATCATCAGCTAATAAAGCCTCTAATAAATCATGATTTAAGCTTCCTTTTTTAGCGTATTTAGCATCCTCATCAAAATACAAATTGAATTTTTGCATCATGAAATGGTCTAATATTGTATTTCCAGGACCAACATCGGTAGAGAAAATATTTTCCGACTTTCTTTTAGCCGGTAAATAAGTAAAATTAGCTATACCGCCAATATTCAATAAAATCCTATCTATTTCTTCATCAGCAAAAAGCAAATAATCACCATAAACAGCAAGCGGAGCGCCTTCTCCACCTGCTGCAATACTTTTTTGTCTGAAATCACTTAGCGTGATAATACCTGTTAAATGTGCGAGATGGTCGCCATCGCCTATTTGTAAAGTAGCATCGGGATAATTGTTAAGCTGATGCTTGATTTTGGGTGCATGGTAAACCGTTTGACCATGACTAGCAATAGCATCTATATCAGTTGCTGTATAAGCCCACTTTTTTAAAGTGTGGTTTATAATTTCAGCATGTTGCCTAGCTATTTGTGCATTTAGCAAGCATAGCAATTCTAAATCGACCGTTTTTTTAGAGAAAACTTGTTTAATAGCTTCTTTAAAGGAGCTTTCATAAGGGTAAGTTTCAAAATGTAAGATTTCTACCCTTGTACCTAAGCCAGCACCTTTAAATTTGCATAAAGCGATGTCTAAGCCGTCTAAAGACGTTCCAGACATGAGGCCAAGAATAATTCTCTCTTCTTTTTGAGCAATTTTGAAAAGCTTCTCTAAATTTTTATTCATCTTAATAACTCATGCTTACAATTTTGGCAACATCTGCCGGCGTGATAGATTTATGCTCACCCAAGGCTTTCCAGCCTCTTGTATTAAATCTTTCCTCAATACTTTCTGCGGTACCTTCGTAAGTTTCTGTATATTCAGAAAGTTTGGTTTTTATGTCCAAAGAATGGAAAAATTCTTCTGTTTTAGCAATAGCCTGTGTAGCTTTCTCTTCTACAGAACCTTCCTGGATATTCCAAACGCGTTCTGCGTATTGGGCTAATTTTTCTTTTTTCTGTGCTAAATGGTAGCGGTAATGGCTGGGTGCAATAATAGCTAAAGTTCTGGCATGGTCAATTCCGTATAAAGCAGTAAGTTCATGCCCTATGGCATGTACAGCCCAATCTGTTGGTACACCTTTTTGTATTAAACCATTTAGAGCCATGGTACAACACCACATAAAATCTGCCGCAGCGGTATAATCAGCTGGGTTTGCCATTACTTTTGGAGCAACTTCTATTAAAGTTTGCATAATGCTTTCAGCAAATCTGTCTTGTAAGCAAGCGCCAATAGGGTAAGTCATGTATTGTTCTAAAACGTGTGTATAAGCATCGGTTATACCGTTTGCAATTTGCCTTTGCGGGATAGATTTAATTACCTCGGGGTCTAAAATAGAAAAAGCAGGAAACAAGCCTGGGCCGCCCATTGCTAGTTTTTCTTTTGTTTCTGCTCTTGATATAACCGAACCAGAATTCATCTCAGAGCCTGTAGCAGGCAAAGTTAAAACAGTACCAAATGGCAAGGCAACTTCTGTTCTGATACCATGGGCTAAAATATGCCAAGGTTCTTCGCCTTCATATAAAGCGGCAGATGCAAGAAATTTAACACCATCTATCACAGAGCCTCCGCCAACAGCTAGTATATAATTGATGTTTTCTTTTTTAATGATAGCTAAAGCTTCCAGCAAGATGGCATATTCTGGGTTTGCTGGCACCCCACCAAACTCTATTATTTCAAAACCTTTTAAAGCTTGGGTAACTTGCTCATATACCCCATTGCTTTTGATACTTCCACCACCATAAACCATTAAAATTTTAGCATCTGCTGGTATTTCTTTGCTTAGGTTAGCAATTTGTCCTTTACCAAAAAGTATTTTGGTAGGATTTTTAAACTCAAAATTTAACATCTCTTATCAATTTATTACGCTCTTCTCTAACAAAAGTAGTTCCTCATAAGTTCTATTTTATCTTTAAAATGTAATGTTCCCTAATTTAAAGCATTATCAATCTCTTTAAGTATTTTTGCGCACTATGGTAGATATCATTCTAAAAAAGGCAAAAGAAAAAGCTGTTTTACAAAGACATCCTTGGGTGTTTTCTGGCGCATTGGCACAGGTTAAAGGTAAACCACAAAATGGCGATGTGGTTAAGGTTTTAGATGCTGATGCTGATTTTTTAGCTTATGGATATTATAACGACCAGTCTAGAGTAGCTGTAAGATTATTAGATTGGGATGAAAACGCTATCATAAATGAGCAGTGGTGGAAAGCCAAAATTGAAGCCGCAATAAAAGCTCGTGAACATCTACAAAATAATGATACCACCACATGTAGGTTAATTTTTAGTGAAGCTGATTATTTGCCTGGTTTAATTGTAGATAGGTTTGGAGATTATCTGGCTTTACAAATTCTTACCAGTGGCATAGAGAAAGTAAAAGAAACCATCGTCCATACTTTATCAACTTTATTAAATATTAAAGGTATTATTGATAAAAGTGACGCTTCTGCCCGGGCGCATGATGGCTTACAAACCCAACATGGTACTTTACTTTGGGGCCAGCTGCCACCAGAATTTGTAGAAGTTAAGGAGAATGGCGTTAAATACCTGATCAATATTTTAGAGGGACAAAAATCTGGTTTTTACTGTGATCAAAGAGATAATAGAAAAATAGTAGCTTCTTATGCCGCAGGTAAAAATGTTTTAGATTGTTTTAGCTATAGCGGAGGTTTTACTTTAAATGCTTTGCTAAATCAGGCTGCTGCTGTTACTGCTGTAGATAGCTCTGCTTTGGCTGTAGAAACTTTAAAAAAGAATATCCAACTTAACCAGTTTGATGAAGGTAAAGTTATTGCTGTACAGTCTGATGTAAATAAATACTTAAGGATATTGAAAGAGAAGGGACAAACTTTTGATGTTGTTGTACTAGACCCGCCCAAATACGCACCTTCTCGTTCTTCTTTAGACAGGGCCGCTAGGGCATACAAAGATCTTAACCGTTTAGGCATGCAAGTTCTTAAAAAAGGCGGTTTACTGGCTACTTTTAGTTGTTCTGGAGCTATGGATATAGAAACTTTTAAGCAAGTAATTGCTTGGGCCGCACTAGATGCCGGTAAAGAAGTTCAAATTATCTATCAGTTTTGCCAACCAGAAGATCATCCCGTAAGGATTTCTTTTAGCGAAGGCGAATATCTAAAAGGCTTATTTTGCAGAATTTATTAAAACTTTTCTGCTCCAGATAAGTTAATGCTAGCAAGTATTAGATAAAATGGAGCAGGATAACACTTCACAAAGCAAGGAAAAATCTCTTTATTATACGGGTGAAGCCAAATTTTCTCCGGTACCTTTAACGGTTAGCTCTCCGGTAATTAAACCTATTGATAAAAATAAGTTAAGGGCAAATGCGGTAGAGTCTATGCATATGCAGGCCAATCAGCAAATTACTATGTTGCGTAAGCAGGCAGAATTGATTATGGAGCAGGTTAAGGATATTGAGGAACGCCTAAAAATATCAGAATTGATTTACACTGCCGAGATGAAGTTCAAGCCCGTTATTGGGCAATTATATCATCTTTATCAAAAAGAGGATCATACCTTTTTGGTGAGTATGATAGCGCCAGCGGAGTGGGGCAGATCTAAAACCTTCAAAAAGTTTGTTTCTACAGTTAAGCTTTTAGCAGACCATACTTGGGAAGTTTTGGATAAATCATCTCTTAATTTTGATGACTTTGAAGAAGCCATGCCATTAAATCAGGATGTTTAAACTGATAGTTTAAATCTTTCACCAATTTATCTGGGTTAATGATTTTAAACTTCCCTTTCTCTTCTATAAAATCAGCTTCGGTGTTGTTATAGATAGCTGATGCTAAGCTGTAAAACTCTTTTTTGTTGGATGACTTGGAGCTGCAGCATGGATAGTTTTCCCCCAATAATCTTGCTTGATAACTTCTTCAATAATACCAATACAATCATCTAAATGGATAAGGTTAACAGGTATTAAACCATCTGGTATTTGAGTTTTACCACCAAAAAATCTTCCTGGATGACGGTTTGGTCCAATTAAACCAGACATTCTTATTACCGTAGTTTGGATATTTGGGTTATTTCTGAATACTTCTTCTGCTAGAAATAAGCGTTGTGCCGATGCATTTGCGCTGATGAAACTGTCCTCAAATACGACATCATTATTTTCTTCATAAACAGAAGTAGAGGAAACAAAAATTAATTTTTGGATCTTACTTTTGTTGATGTAGCTATTCAATCGAGCTAATTTATGTGGATAATCATCCGCATTGATATGATTTCTACCCGGCGGAACGTTAATGATTAATATCTCATTATCTAAAAATTCCATCAACTCAGCTTCATTAGACAAGTCGTCTAATTGTATCAAAAATGATACAATTGATTGTCTGCTAATTTCTTCAAGTTTATCTTGCTTAGTAGTAGAACCTTTTACCAATTTACCTGAACCGACAAGGGCTTTACCCAAAGGCATTCCCAGCCATCCGCAACCTAAAATACTTATCATCAAATTAATTTTTTATTTTTGGCATTCGCTTTGACAAACATCATTGTAAATATCAATATAAATAATATGAAAACTTCAAGATTAAAAATATCTGTTTTAGGATTAGCTTTTGCCATTGGCGCAACTACTATTTTACCTGGATGTGATTCTTTAACTAGCACACAAAAAGGGGCTGGTATTGGTGCTGCTGCTGGTGGTACTATTGGCGCTTTAATTGGCAACAAAGCTGGAAATACAGCTGTTGGAGCTATTATTGGTGGTGCTTTAGGTGGTACTGCGGGTGCTTTTATTGGTAGAAAAATGGATAGACAAGCAAAAGAATTAGAGCAATCTATACCAGGTGCTGAGGTTATCCCAGCAGGTGAAGGTATCATTGTTAAATTTGATTCTGGTTTATTGTTTGAATTTGGAAAATCAACCTTATCTACAGCTGCTAGACAAAACATAGATAACTTAGCGGCTTCTTTAAACAAATATCCTGATACTGATATCATGATTATTGGTCATACAGACGGTATTGGTTCTGATGCGGTTAATGATAGACTATCTTTAGAAAGAGCAAACGCAGTTAGATCTTATGCAGTTTCTAAAGGTGTAGATACTGGCCGTTTAAAATCTAGCGGTAAAGGTAAAAATGAGCCTATTGCTTCTAATGAAACTGAAGAAGGAAGAACACAAAACAGACGTGTTGAAATTGTAATTGTTGCTAACGAAGCCATGAAAGCAGAAGCTAAAGCAACTACCAACAACTAATAAATTTTAAGTGATGATACAGAAAGCATCTGCCTAAAAGCAGGTGCTTTTTTTATGCCATTACAGTAAGCATTTTTAATACCGGAAGCGCTAAATGACGCTCGCCATGGATTTGATAAAATTGGCCTGCCTCTTCTGCGTGAATGCCTTTGGAGAATAAAAGCCATGCAATTTGTTGGTCTATATAAATAAGTGCATCCGCTTGTTTATGCGCTTCATCAAAAACCCAAAATCTTTTATCTTTTTTAATGGTCCAGCGTTTGCCCGCAGGCCCTACAATTTCTACTGCTACACTTTTACCAATTTCTGCGTTAATTTTTTGATAGGTATAAGGCAGGGCTTCCATAATAATTTCTAAGTAGGGGCTATAAAATTTTGGTTCTAGAAGCTCCTGATTATTAAAAGCAAAACGTATTTGTTGTTGGTGAAGCCATCTTTCAGAATATTCTCTGGCAATATCAAACCAATTTTCTGAATGTGATTTTCCGGCCCATGTAACCGGAAAAAGAGCCATATCAAAAGGGTCTAAAGTCTCAAAATAAGCTATTAAATCATCTTGATATTTGCTTATCAGCTCTATTAAAATATTTGGGCTCAATCTTTTTGATGCAGCCACCCATTCCTTATTGATGTTATTAATATGGGCTAATAACTCTTCGTAAGTAGAAAATTCTTGTTGTAAATGTTGGTATTCATCTCTCCCTAAAGACAGCCTTCTTATGCTAGTATCTAACAAATGTGCTGCGATGTCTTTTACCGTCCAATCCTTACATACTGTAGCTCTTTGCCAATCTTTTTCATTCAATTGTTTAAGAAAATCTATTAAAGCTTGGTTTAAAGGCTGAAATAAGGGCAAGAAATCAATCATACCCCGAAAGATAATAAATACTGTAATTATGCCATAAAAAATGGCTGCCTTTTTTAAAAAAAGACAGCCATTTTATAAAATTATAAGGTATTTATCTACTCGGTCTTCCAGATCTTGAACTGTTTTCTGAGCTACCTCTACTACTACTTCCTCTCTCACTACTTCCGCCTGATGGTCTTTTACCAGAAGAGCTTGGCGCAGATGGCCTTTCTACTCTTTGAGGAGCAGACGGAGCTCTTTCTGAGCCAGAAGATCTTCTGCTATTATCTCCTGAAGGGTAACTTCTGCTCTCTGTTGGTGTAGAAGATGGTCTTTCTCTTTCTACGCGTTCTGGCCTGTTGTTATCATCAGGTCTAGATGGTGCTGAGTTTCCTGTTTCTGGTCTATCAGAAGAGCTAGGTCTTTCTACACGCTCTGGTCTGCTATTATCATTAGGTCTAGACGGCATATTATTTATATCCGGTCTTTCAGGAGCATTGTTTCTTTCTACACGCTCTGGTCTGCTGTTGTTAGAACTAGACCCCCTACCTTCTGCATTTCTGTTTATCTCTTCTCTACCAGTAGCTCCACTGCTACGTTCTGGTCTAGCATTGTTCTCAGTTCTATCCAAAACCCGGTTATCATTAGAAGAAGATGGTCTTGTACCAGTTTCTGTTCTTGATGGTCTAGAAGAGTTATTAGCTATTGCTCTTGGCGCTGCATCTCCTCTTGCTTCTACCTGCGGACGGTAAACATTCACCGTACCTCTTTCTATCCTAGCAGAACTTGGTCTGTTTGTATCGTTAACTTTATATACCGTAACATTTTGTCTGGTAGCTCTTCTCACATCTTCAACCCTAGGGCCGCTGTTATACCTAACGTTTCTGTTCACTACATAAACATTATTGATAACGGTTGTATTTCTAATAATTACTACATTTCTTCTTGGCTCCCAATACCTTTGATATGATGGGTAATAGATACATCTTTGAGGGATAAAAACCCAATAGTGATCTGGATAATACCTTCTTCCTATATTGATATTAACAGATATTCTTGGTCCTAAAGGTGCCCATCCATAATAACCGCCACCGGTTCTCCATTCTACCCATGCTGGTCCCCATTCTGTATCGGGTAACCAAATCCATCCATCATAGCTATCGTAAAACCAACGTCCATAATGGAAAGGAGCCCAGCCCCATTCAAAATCTGAAACCCAGGTATTGCCATATTCTGTCATTACCCATCGTCCATTGGTATAATAAGGTCTAAAATCTCTTCCAACATTTGGTCGCCAAACGTAGCCGTATTCTTGGTTATTTACCCAATCTCCATGATAAGAAAGCTCATCATAAAAGGTTTGTAAACTAACACTTCTACCTTGCGCTTGGCTAGTGTTAGCACTTAGGATTAGGAATAAGATACTTATCCCCAAAACTGATAAAGATTTTTTTAATCTGTTCATGGTACATTTTCCTTTCCATTTTTTAAGGAATTATTTATAAAACGTTATCAAGAAAGCTTTTCATACAAGCATTGCTATAATTTGACAAGCTTCAGATATTTACAAATAATTGGTTGTTTTAACGGTTACTAAACAACCGTTTATAATAGTAAGACGCATAAGAAATAAAAAGGTGTCAATAAAAATTAGATTTTTTTATTTGCGTATTTCCTTTGTTAAAATCACGTACTTTGCGGTATGACAAAAGGCACATTATATCTTATCCCGGTTGTTATGGCAGAAAATGCTGTTGCAAAGTCTTTAACTCCTTTTTTGGTTGATACCATAAATACTATAGATGAATACATTGTAGAAAACGAGAAAACAGCCAGAAGGTGTTTAAAAGAAGCGGGCTTGAAAACGCCACAGAGTGATTTAATTATTCATGATTACGGAAAACATAGTCGTGGGGGCAGCTTAAAACCTTATTTCAAGGGTTTAGAGCAGGGTAAAAATGTAGGTTTAATGAGTGAAGCTGGTTGCCCGGGTATTGCAGACCCCGGTGCAGAAATTATAGCCGAAGCGCATAAAAGGAATATAAATGTTGTACCCTTGGTAGGGCCAAGCTCTTTATTATTAGCCTTAATGGCATCGGGCTTTAACGGACAAAGCTTTGCTTTCCAAGGATATTTACCTATTGATAAAATGGCCAGAGCTAAAAAGATTAAGGATTTGGAAGGCTTTGCAGAGCGTTTTAAACAAACACAGCTTTTTATTGAAACGCCTTTTAGAAATAACCCCATGTTAGAAGAGATTTTGAGAACATGTAGGCCAGATACTTTGTTATGCATAGCAAGTAATTTAACTGCTGAGGATGAGTTTGTAAAGACTAAATCTGTTGGCGATTGGCGGAAAGAGGCACCTGATTTGCATAAAAAGCCTACCATATTCTTATTATACAGAACAAAATAATGTTTAAACCCGATACAGATGTAAGCATTTACGGCATCAATATACCTGCTTTGTTTTTGGCTGTTGCCTTGAGCTATAATGGCGTATCGGTTTTTATCTGGGCAGAGCAAGAAAAGCCAGATGATTTTCCGGAGGAGTTAATTTTTGACCATTATATGGGTCATTTTTTAAAGCAATTTGGTTATCAGGTAAAAGATAATGCTGATATGATTACTGTTTCTGGCTTTTTAGAACAGAGCTTAAAGTTATTGGCAGGTAGGGTTTGTCCAGTAGTTTGGAAATCATCAGAGAAGAAAATAGGAGAGGATTTTACATCAACATTAACCCTTCAAAAAATATCCAAAATTAATCCTTTAGTGTATAAAGCAGAGGCTTTACTTTTAAATAATAACCTTGATTTAAGCTTTAGAAATATCTTATTGTTAGGCTGGCGAATGAGTGGTTTGATAAATGGTACCCTAAATCAAAAGGTACTTTTAACAGCTGAATTAGAAAAAACATTATTGCAAGAACAATGGGAGCAAAAGGTATTTAAACAATCGGCTTTTAAAAGGTTGTTGGCTAAAATTCATCAGCCTAAGGCAAAAGTTTATCAATTAATTGATGCTAAAATAAACCTCCATTTAAGTCAGGACAGAAGTTTAGAAGCTGGGGAGCTTTTGCCTGATTTTAACTTTTATGATGAAAAAGCTCAGGTAGATATCCAATTACATCAATGGACAAATTACAAGCATTTTTCGGTTATCCTTTTTGGTTATTTATCTCAGCCAAATTTATTTACCGTTTCTCGGTGGGTGCAGTTAAACTATCCGGTAAAACTTTATTATTTACCACCTAGTGAGAGAAACGAGCCCCTATTTGAATTTATGGGCGTAAAACCTGATACAAAACGGACCTTTATTGTAAGACCAGATTTGTATTTGGGCCTTATTCATGATACCATTGATGTTGAGGTGATAGATAATTACCTTAAAAACGTTTTAGAGATGAAAGTTAACCATGAAAAAAGAGATGCTTCTGATGCTTCAATTTTATAATAAAAAGGACAGTATCCTACACATTATGTAAGTCTGTTCTTACGTTTATCCTACGTTCATCTTACGTTAAGCTTATAATATTTGATGAATGATGGTAAACAGGTTATTAGTTCTTACGCTCCATTTATGTTTTTCCAACATTTCTCTTTATCACTAGCAAACATAGCCTCTATAACCTTCATATTGTTTACAGCATCTTCTAAAGGTGTAGGTACATTTGTATTGTCTAAAATAGCTTTAGAAAAAGCATCAAACTGTAAAGTATATTGGTTGGTGATATCAAAGAAAACGTCTTTTTGCTCATCGGCCTTAAAAAGGCTTATTTTAGCTGGTTCTAAAGGTTTGGCATTAAAAGGTATTTCTATTTCTATACGACCTAAATCTCCAATAATATTTACCCTTTGGTAAGGTACCAATTGGGTAGAACAGGTGAAGCTTGATACGCCATTGGCAAACTGCATCATTCCTGATGATATGATGTCGGTTTTCATTACCGGGTCATAATCAATATTAGAAGCCACGTTTAAAGGCTCTGCATCAAATAAAAATCGCGAAAGCGAAATGCAATAGCAACCAATATCCATCAAACCGCCACCCCCAATTTCTGCTTGATTGCGAATGTTCTGCGGGTCTACATTATAATAAGAGAAAAAAGATTGGATAACTTTCAAATCGCCTATCCACTTTTGGTTTACCAGCTCTTTTGCATGTATCCATTGCGGGTGAAACCTATACATAAAGCCTTCCATGACTTTTAGATGAGGATATTTTTTAGCAGCTTCTAAAAGAATTTGGGCTTCTTTACTCGATAATCCGATGGGTTTTTCACACAAAACATGTTTGCCTGCTTCTAAGCATTTTATGCTCCATTCTACATGCAAATGGTTGGGTAATGGGATGTAAATGGCATCTATATCAGCATCATTTAACAGTTCTTCATAAGTGCCATAAGCTTTTTCAATACCTAAAAGTGTGGCTGCTTTTTGTGCCTGAACTAAATTTCTAGAACAAATAGCATCAACCTGAGTGAAGTTACAGTCTTTAAGAGCAGGTAAAACCCTATCGGTAGTAATTTTTGCAGTGCTTAAAATGCCCCATCTAACTTTTTGTGTCATTTTGTTTTTCTTTAGGTTTATCCATGTATAGTTTCGCTTTTTCCGTAGCTTTTGATGATGACGCCCTCATAATCTAACCATTCTTGCCAACGTTTTTCTACATCAATACCCTTACCGTATTTTCTGGCTAAGCCGATGAAAAGCGTATAATGTGTAGCCTCAGAAATCATCAATTCATGGTAAAAAGCAGCTAGTTCATTATCTGCAACATGTTCTGATAGTACTTTGAAACGCTCGCAACTTCTGGCTTCTATCATCGCGGCAAGCAAAAGACGGTCAACCATATTTTCTGTTCTTTGGTTTTCGCCTCCGCCCTTTTTCAAGAATTTCAAGAGCTCGTTAACGTAATTGTCTTTACGCTCTTTGCCAAAAGTATAACCTCTTTTAATGATGATTTCATGCACACGCTTAAAATGGTCCATTTCTTCTTTCACCAATTCCGCCATTTCTTGTACCAATTCTGGCACATTGGGGTTTTGGATAATGAGGGTAATGGCATTGGTAGCTGCCTTTTGTTCGCAGTAGGCGTGGTCTGTTAAAATTTCTTCGATATTACTTTCTACCACATTTTTTACCCAAAATGGGTCTGTTGGTAATTGTAATTTAAACATGGTTTTATCGCTCATAACAGAAAATTAAGCTATTTATACAAACTTTTACTCTCTATAAACTCTAATACTTCTTCTGGTAAGAAATACTGTACATTTTTATTTTCTTTAATGGCTTTTCTGATAAAAGTAGAGGAGATTTCCATCAGCGGAGTTTGGGTAGTGGTTACTGATGGATGATGGCTAAGTTCTTCATCAACATAACCCGGTCTTGGATAAACATAAATATGATAATCTCTTAAAATAAGCTCATAATTTTTCCATTTCTTGAGGCTTTTCAGATTATCTGCACCCATAATCAACACAAAATCATGTTCTGGGTAAATATCTTTTAAGTGCGTGAGCGTATCTATGGTATAAGATGGCTGCGGTAGTTTAAGTTCTATATCGCTTACGCTGATATTCTCGCTCTTCTCGGTAGCTATTTTAGCCATTTCTAGCCTATCATAAACCTGAATAAGGTCTTTTTTATCCTTTAAAGGATTATGAGGAGAAACTACTAGCCAAACTTTATCTAAAGGGGTATGGTTGGCCATATAATTGGCAATAACCAAATGCCCGGTATGGATAGGGTTATAAGAGCCAAAAAATAAACCAATTTTCATTGTTTTAATTTAACTGTTTAAAAAGTTAGCAATTAACTCTTCTGCTTCTTTACAAGCAGTCTCTAAGTCGTTATTTTTTAGAATAACATCAAATTTAGAAGCGTAGTCAAGCTCTTTTTCTGCTTTTTTTATACGTTCTGCAAGTTTTTCTTCAGAGTCTGTACCTCTTCCAGTTAACCTTTCTATTAAAACATCTAAAGATGGTGGCTGCACAAAAATAGCCAAAGCATCTTGCTCAAATTTCTTTTTTAACCTTAAGCCGCCTTCAACATCAATATCAAAAATAACATGTTTATCCTCATCCCAAATTCTTTGTATTTCACTTTTTAAAGTGCCATAAAAAGTTCCGGTATATACCTCCTCAAACTCTACAAACTCATGCTTAGCCACACGGTGTAAAATTCTTCATTACTGATGAAATAATAATCTCTGTTATTTACCTCATCGCCTCTTAATTGTCTGGTAGTTGCCGATATAGAAAAGGAAATTTTATCGGGAAATTTATTCAGTAAATGATGAACGATAGTGGTTTTACCTGCTCCAGACGGTGCCGAAAATATAATGAGTTTGCCTTGTTTCATTCTTTAAAGTTGAAAGTTGAAAGTCGAAAGTTGAAGGTCTAAACTTTAAACCTTGAACTTTTTACCTTAAACTTTATAATACGTTTAACAGTTGTTCTTTAATTTTCTCTAATTCTTCTTTCATGCTCACCACGTTTCTTTGGATATTAGCATCATTAGCTTTAGAGCCCATGGTATTAATTTCTCTGCCTATTTCTTGCGAGATAAAACCTAACTTTTTACCATTAGCATCTTTATCTTTTAAAGTTTTGATAAAATAATCGCAGTGGCTTCTTAGTCTTACTTTTTCTTCTGTGATGTCAAACTTATCTATATAATAGATAATTTCTTGCTCTAACCTGTTGTTATCAATGTTTTCTTTGCCAACAGCATCTGCTAAATAAGTGTTTAATCTTTCTTTAAAAACGGGTACGCGGTTAGGTTCATCTACCTCAACTTTTTGTAAAAGCGTTAAAATATTTTCGATACGTAAAATCAAATCTTTTTCTAAAACTTCACCTTCGTCTGCTCTAAATTTTTTAAAATTCTCTAAAGCAGTCTGAAAAGTGGCTAAAACCTGGTTCCATTCTTCTTCAGAAACAGCATTCTCATCATATTTTACCACTTCGGGTAAGTTGATAGCCAAGCTTAACAAGTTGTTGGTATTTTCACCTAGTTCTAAAGCGGTATTTTTAAGCTCTTGATAATAATATTTCAATAAATCTTGGTTGATGGTGGCTGCTTTAGCACCAGCATTATTACTTTCTATATTGATAGAAAGCATTACTTTACCTCTTTCTATTTGCTTATTGCACTCGTTTCTTAGGAAAAATTCTTTTTCAGAATAGGCTTTTGGTAATTTCAGGTTAAGCTCTAAAAACTTACTATTAAGAGACTTAATTTCTACGGTGTATTTTCCGCTGTCCAGATCTTTGGTTGCCGATCCGTAACCAGTCATTGATTTTAACATTTGCAAAGATAAAAATTAATCTATTAAATGGATGGTGCTTTTCTATATCCTACAAATGTTAAAAAAGCTAAAACATAGGGCGCTTAAGGAAGTTAATCTTAAATTTAAGGTCTATGAGGTATCTGCTGTTTTTCTACTTATGCTTTGCGTTGCTGCCTTGGTCTTACGGGCAAGAGCAGTTTATCCTTAAAGGTGTTGTTTTTAGCGATTTAAACAAGCAAAGATTACCTTATGTGAATATCATCAATCAAAGGACACAAGCGAGTTTAAAAAGTGATGAATGGGGCGTTTTCTCTATTCCAGCACAAATAGGCGATACGATTTTGATTCAGAAAGAAGGTTTTCAGGAGTTTAGTAAAAACATCAGCGCTAAGCAAAATTTGGTAGTGTATTTAAAAGGCGTTATCAAGTTAGAAGAAGTGGTGGTAACGCAGCCTTCAAAAAAAGCCGACCAAAAAGAGGTTTTAGACGATTTTAGAAGTAAAGGTGTTTATTTTAATGGTAGTCCGCCTTTGTTGTTTTCTATTTTTCATCCTTTAACAGCTATACACGAGCTTTTAAGTAAAGATGCTAATAATGCACAAAGGTTTGTACAATACATCAGCAGAGAAAATGCCGAAAGTGCTGTAGATAGGAAGTTTAATAAATGGCTGATTATGAAACATATTCCTATAAAGGATGAGGATGTAGCAGAGTTTATGTTCTTATACAGACCTAAACCCAGCCAAGTAACCTATTGGAATGATTATGATGTGATTAAGTATATTAAGGATTCTTACGAGAAGTTTAAGAAAAGAGAATCTAGATGAAGAGCTTATTATTCTATTTATAGGATTGTACTTGATTAATGTTTCTTAATAGTTGTTTAAATTTTATATTAAAATCATTTCATTGTAGCAGTTAACCCATAAGATTCGTAATTAATTTAGTTAGGAACTTACTATCAATGAAAATTTTTGCCCAATGCTTTTATTTAAGAAAAAGCTGTTTATAAGTTGATGCTACTAAAATTTTTACTTTATGAAAAACTCAAGACTCCTTTTATTTTCTTTAATTGTAGCTACTTTAACTTTTTCTGGATGTGATAAACAAGAGACAGATTGTGGCTTTCTTAGTTTTGAAACTGTCGATTTCAGAAATTATCCTTCTTTAGGAATTGTTAATGGTGATGAGGAGGATAAGTATCTAGTTATTAACTCTAAAGCTGAATTTGATGAAAAAGTGTTTATTTCAGAAGAAGATAAAGAGCGATTTCATTTAGATTATAATAAGTACACGCTTCTTCTTGGAAAAAAAAGAATTGGAGGGATACCAGGAGGTTTAATCAGCCAGACATGGCAAAAAGAATGCGGAAGTACTAACTACATTTATAAAGTTGATATAAAGAATGGAGGTTATACTGCATTAGGTAATTTTTATTTTGGTATTATCGTAGATAAGGTTAGCGCCGATGAGGTTATGTTTGATGTTAATTTAAGCGAATAATATCTAATTAGATTTAATGCTAAATTATTTTAAATACTATAAGCATTAACTTGATTCCGAAACTATTATTAACTGTATTTTTTTTCTGATAATCAACGTATTATCTTTAAAACATAATTTTGACTAAATTCAACTAATATCTAACTAATAATATCCTACAATATGAAAAATTACATTATAATCTTACTATCTATAATATTAATAAGCTGTAAAGAAACAAATAGCTCTTTTATAGAAAGTGATAATTTTAACGCATGTGGAGTTTCTTCATTTAGTCAACTTAATTGGGCTCAGGATCTTGTAGCAGGTAAAGGGGCATGTAGTCAAATTTATTCAGGGGCTAAACTTACGATGTATGATTACATGGGGGTGAAAGTTTTTTATTTTGAAAATTTAGCATCATCCACAGGTAGTTGTAATAGGATCTTGTATAATTGTTCGGGTATGATTTTAATATCAGCTAATTCTGAGCAAAGCATTTGGACGGATTTTGAAAACAACAAAACTAACGGTAAATTAATATGGAGTATATAAGAATCTGAATAATTATCAAATCAATCAAACATCATGAACTTAAAATTTAAAATTATTATAATTATGGTAGCCATAAACATAATTGGAGCTAAATGTAAAAAGGAAGATTATAATGAACGATGTACTAGTTGTGAAAAACCATTATTTGTGCAAACATTTAAAAATATAAATGGTGAAATTAGAAAAGTTGTTAATCTTGAATATAGATACAATAATAATCAGTTTTATATTCTGGTTGATGCTGAAATATCGCTTCCTCAAATTTATACTAATATTAATCAAAAGTATGTGAAACTATTTTCTTGCTCTGCCTCAAATTATACTGATGTAGATATAGGAAAGACAGTTCAAATTTCAGGAAATCTCTTTAATTGTACCACTGCCAATCATGGTGCGCCTACTAACAATCTACATACTTTTTTAATTTATAATAATTGAGATTATGAAAAAAATTCTCTTTATAGCTGTAATTTTAATCTCAATAAAACTGAACTCTAAAGCTCAAACAACTAATATTGTAGGAGGAACTATTATAGATATTAGTAATGTTCCTTGGCAAGTATCTTTAAAAAATATTTCAGCTGGAAATCAACATTTTTGCGGAGGTTCAATTTTAAGTAATACTTGGATACTCACGGCTGCTCATTGTGTGGTAGGTATTAATGCCAATAATTTAAAAGTTCATGCAGGCTCTTCTAATCAGACTAACTTATTGGAAGGTCAATATATTCAAGCAAGTGAAATAAAGATACATCCTAACTATAATCCACTTACCAATGATAATGATATTGCGCTTATTAGATTATCCTCACCTCTTTCTTTCAACGAAAATGTCAATTTAATTGAATATGCAAATGATTGTAATTTACCGGATAATTATCTTGACCCCGGTAATATAGCTTCTTTAAGTGGATGGGGGCTACAACAGGTAATCCGCCTTATGTTGTAACGTCTATGCTGAAAAGTGTTCAAATGCCTATAATATCTAATATTGATGCTAATAATTTGAATGGAAGTAGTATTAATGTTACCTCTAATATGTTAGCATTTTATCAGTCTGGTTCTGGTGCTGCTCCTGGGGATAGTGGCGGTCCTGCAATTATAAATGTTAATAATAAGCCTATTTTAATAGGTGCTTCTAGCTGGGGTTTATTACCTAAAGATCAGAAACCTACTATATATACAAGAATTAAAAATTATGCAAATTGGATTAATCTTAATACAGGTGTTAACTTTTCTCATTATTCAGTTTCAGGCCCTTCCCAATTCTGCACCACTACCACCTACCAAATCCCAAACTTACCTAGTGGTGCAACCGTAACATGGAATGCTACAGGTAGCATTAGCATTTCTGGTTCTAACACAGCAAACCCTGTAAATATGAGCAAATCTATAGACGGCACAGGAGCATTAACAGCAACGGTAAATACGGCATGTGGAAGTTTTAATTTGTCTAAAATGATTAACGTAGGAGCACCCACTTTAGGAATGCCTAGTTTTACAAATTTAGATAATCAAAACCCTTATTGGTGTTCAAATAATTCGGGTAATTCTTTTACTATAGAATCTAATGATCTTAGTTCTACATATGAAGCAAGGTTATTAGCATATCCATCTTTAAATGTATATGCTACCAATAGTAATGCTTATCCTGGATTTGATGTTTTTGGTTATGTTCCACCTGGTTATTATGTTTTTCAATTAAGAGCCACAAATGCTTGTGGTACATCAGCTTGGGTAGAAACAGAGGTAGAATCTGTTTATTGTACAAGCGATTGGGAAAGCAATAATTTAAATGTTTATCCAAACCCTGCTAAAGAAACCCTTACCATAACTTATGAAAATACAGAAGGAATGCAAGCTTTTGAACTATCAAAAACAGCATCAGAAGAAAAACACCTACTTCTTTTTGATGATAAGGGTAAGGAAGTTAAAAAGGATATGATGAAGGCAGGAGATACTAAATTGGAATGGGATATTAAAAACCTTCCAAGCGGTCGTTATTTTCTACATATAAAAGAAGACAAGGAAGTTATCAAAAAGCAAATCATCATCAAACATTAAGAGATTGTTATATCCAAACAGGAGGCTGCCTCAAATCACCACTTTGTGTCAGGCTGAGCGGATTCGAAGCCTTTTCTTATCCTTCGACTCCGCTCAGGATGACATTTCCTTCGACTCACTGTCTACCGGACAGACAAGCGCTTAATGTGACAAATATGATTTTTGAGATAGTTTGCTGTTTTACTTAAATGTTTTATAAATACCTTCTTAACTATTCACTTTAATATCACCCAAATGTTCTACATCTTTTAAATCATAAGGTGTTTCTTGGTACACAAAATAGTTTAACCAATTATTGAAAAGCAAATTGGCATGGCTGGTCCAGCATACTAAAGGTGGGTTTTTAGGGTTGTTAGCCACATAATAATTTTCTGGCATGGCTATATCCAAACCTTTTTTAGCATCTCTTTTATATTCTTCATGCAAGGTTAAAGGCGCATATTCAGAATGTCCGGTAAGGTAAAACTCGCGTCCACCTCTGGAAGAAATAATGGCAACACCAGCATCTGCAGATTCTGATAAAATAGAAACCCCTTCTTTATTGGCAATATCCTCTTTTCGCATGGTGGTATGGCGACTGTGAGGGATAAAAAACTCATCGTCAAAACCTCTAAACAAAGGGTTGGTTTTTTCTGTTGCGCTATGTTTATAAACGCCAAATAGCTTTTTATCTAATGCAATTTTCTCTACACCATAAAAATGGTAAAGTGCTGCTTGCGATGCCCAACAGATATATAAAGTTGAGGTTACATGTTTTCTGGCCCAATCAAATATGGTGGTAATTTCTTTCCAATAGGTTACTTCTTCAAATTTAAGCATCTCTACTGGCGCACCTGTAATGATCATCCCATCATAAAAGTTTTCCTTGATATCGGTAAAAACTTTATAAAACAGTTCAAGATGTTGTTCTGATGTATTTTTAGATTTATGCGAATCTAGCCTTAAGAAAGTTACTTCTACTTGTAAGGCATTGTTAGAAAGTAACCTAACAAAATCTGTCTCAGCAGTAATTTTTATAGGCATTAAGTTAAGAATGAGTACACGCATAGGACGGATATCCTGTGTATTGGCTCTTAAATCATTAATCACAAATATATTTTCCTTTTTTAGGATTTCTATTGCTGGCAGATTATTTGGAATCTTTACGGGCATATACTATTTAGCTTTTCTGCTTATTGAGCGGCAAAAATAACAAGATTAAACAGGAACTTAAAAATTAAAACAGTTTATGACATCAAAGAGAGATGAAATTACAACAAGCTTAGATAGCTAGTAGCTCGCAAGTTTTTTCAGCAGCTAATTTTTCGGCACTTTTCTTATTAAAATCTATACCAGTAGCCATAGGTTCATTATCAATAAGCACCTGTATAGAGAAAAGCTTTGCATTGTCTCCCTCCTGGTTGGGGACAAGTTCAAACACAATATCCTTAGAGTGTCTTTGGCACCACTCTATTAATTTACTTTTAAAATTAGTTTCGGTTTGTTCTAAGGTGTGTATGTCAATATGAGGCTTGATAATCCTTTGGATAAGGAAATCTTTGGTGAAATTATAACCTTTATCTAAATAAACAGCTCCAATTAAAGCTTCAAAAGCATCGCCCAATAAAGAACTTTGTTTTGAGGTAATGTTTACGGTAGTAGGGTCAAATTCTATCAGCTCGTTAAAGCCTAATTTTTTACCCAATTGGTTTAAATTTACTCTGCTTACAATTTTAGAGCGCATTTCTGTAAGAAAGCCTTCTTCTTTGTAAGGGTACATTTTAAAAAGCACTTCGGCAACTACAGCCCCTAAAATGGCATCGCCTAAAAATTCTAACCTTTCATTACTGTTTTTTCCACCACGTTTGATACCTAAAGCAATAGATCTGTGCCTGAAAGCCATCTTGTATAAAGAAAGGTTTCCGGGCACAAATCCTAATAAATTCTTTAGCGCCTTAACGTATTTACGGTCAGGAGAAAGATGTAATTTATAGATTCTTGATAAGGGCATTTATTTAAGCGCTGTACGTATTCATGAATTTATAGATTTACAGAAACGCAACAGTTTTAAATAATTAATCCTCGTACTTTTTAAAGATTACCGATGCGTTATGTCCACCAAAGCCAAAAGTATTACTTAATGCAGCTCTTACTTCTCTTTTCTGAGCTTTATTAAAGGTAAAGTTTAACTTAGGATCAAAAGCAGGATCATCTGTAAAATGGTTGATTGTTGGAGGTATTATGCCATGCTTAATAGCTAAAATAGAAGCTATAGACTCCACCGCCCCGGCAGCACCTAATAAGTGGCCAGTCATAGATTTTGTTGAACTAATATTCAGCTTATAAGCATCTTCACCAAAAAGACTTCCAATAGCTTTTGTTTCGCTAATATCACCTAGTGGGGTTGATGTTCCGTGAACATTAATATAATCAATATCTGCGGTGGTTAAGCCAGCATCGTCTAATGCACCTTGCATTACCAATTTTGCGCCAAGCCCTTCAGGGTGTGGTGCAGTAATGTGGTTTGCATCGGCACTCATGCCGCCGCCAACTATTTCAGCATAAATTTTGGCACCTCTTGCTTTTGCATGTTCTAAACTTTCTAAAATGATAGTTCCAGAACCTTCACCAGCAACAAAACCTTCTCTGTCTAAGTCAAACGGACGAGAGGCAGTTTGTGGATCGTCATTTCTGGTAGAAAGTGCATGCATGGCATTAAATCCGCCTATACCAGCTTCATTAATGATAGCTTCTGAACCTCCAGAAACAATAATATCTGCTTTATTTAACCTGATGTAGTTAAAAGCATCTATTAATGCATTGGTAGAAGAAGCACATGCAGAAACGCATGCAAAATTAGGACCTCTTAAGCCGTATTTGATAGAGATATGCCCTGCGGCGATATCAATAATCATTTTAGGGATAAAAAAGGATTTAATCTTGGTGTTCCGTCGCCTTTTGCAAAATCAGTAATTTCATCTAAAAAAGTTTTTAAACCGCCAATACCAGCACCCCAGATTACTCCGATTCTATTGGTATTTAGGTTTTCAAAATCTAATCCAGCGTCTTTTACAGCTTCTTCAGTAGAAACTAATGCATACTGCACAAACGGATCTAATTTGCGGGCTTCCTTCTTGTCGAGATAATTTTCAGCGACAAAATTCTTCAGCTCACAAGCAAATTTTGTCTTGAACTTCTCTGTGTCAAAACGAGTAATAGGAGCGGCACCGCTTACTCCGTTGATTAAACCGTTCCAATATTCTTCAACGGTATTACCAATCGGGGTAAGCGCACCTAGTCCTGTTACAACAACTCTCTTTAGCTCCATCTATTAGGTTAAGAGTTAAATTACTTTACATTTTTTTCCAAGTAAGCGATAGCCTGACCAACTGTACTGATGGTTTCAGCCTGATCGTCTGGGATAGCCACGTTGAACTCTTTTTCAAACTCCATGATTAATTCAACAGTGTCTAACGAGTCAGCACCAAGATCGTTTGTGAAAGATGCCTCCGGTGTTACCTCATTCTCGTCAACACCTAATTTTTCAACGATGATTGCTTTTACTCTTGAAGCGATATCAGACATAATACTCTATTTTAATGGTTAATTAATTCTGTGCAAAGAAAAATAAATTCTATTAAATATCAAACCTTTTTGTTTTTCCTCTAATTTTGACAAAAAGCAAGCCGATTTATTTAAGGTTTCCTCGGCTAAATTAAACTTTATTATATTGAATAAGAAATTTTTAAAGCTAGAACTTGATTTTGATTTTATCTTAATCTCAATAACGTCTCCGCTTAAGGACTATAGACTATGCTATCACATCAATAAAAACTTACAATTTGAGTTCGAGAAAATAGAAGATTTAGAGATAACTTATGCCGGGGCTGATACAAAGTATTATTCTCGTTACCTGTATCATGTGGATGAGTTTGCACCAGCATATTACCTTATTGCTAATAAAGGTTTAGGGGGATATTTGGTGCCAGAACTTAAAGAAACCGATTATTTTGTATTGATTAAAGAGTTTATTGATGAGGAAGATTTGAGTTTTTTTCTTGAAGGATTAAAGAAAATAGAAGATATTCAGGTGGCGGTAGAAGTGAATCCTAGGAAGCTAAAATCTAAGGAAAATCTTATTTTTTAACAGATGGATTTGAGTTCGTGTAAAAAATACACTACTTTTGAATTAGAATCTTTTTGTAGATTCATAAAATAATTAGACCAAAGACTCAGAATAAAATATATGAAACTATCATGATTTTGCCGATTATTTCTAGGGATATCATCTAAATCATGAGCGCTTCATCACTAATAAAAATTAAAAAAAGCAAATGAAAATTGTTCAAAAAAGGACCAAAATCGTAGCCACTTTAGGCCCGGCTACTTCAAATAAAGACGTTTTATTATCCTTAATAAAAGCCGGAGTTGATGTTTGTAGATTAAACTTCTCTCATGGTAAAGCAGAAGATCACCAAAAAGTGATTGATATCATCAGAGAAATCAATCAAAAATACAAAACCAATGTTGGTATCTTGGCAGATTTACAAGGTCCAAAAATTAGAATTGGCTTAGTAAAAGATGGCGGTATCAACCTGATTAACGGTACACAAATAAAAATTACTACTAACGAGTGTATTGGTGATGATAATCAAATTTACATCACTTATGAAACCTTCCCTCAGGATGTAAAAGCAGGAGAAATTATCTTATTAGATGATGGTAAACTGCAAATGCGTGTGGTAGAAACTAATAGAAAAGATACTGTTATTTGTGAAGTATTACACGGTGGTATATTAACCAGCAGAAAAGGTGTAAACCTTCCAAACACTAAAGTTTCTATCCCTTCTTTAACAGAAGAGGATTTGGTAAACCTTGATTTTGCTTTAGCAAATGATGTAGAGTGGATAGGTTTATCTTTCGTAAGAAAAGCAGAAGATATTATAGATTTAAAGCGTATCATTAGCAGAAGTGGTAAAACTTCTAGGGTTATTGCTAAAATAGAAAAGCCAGAAGCTATTGATAACATAGACGCTATTATTGAGGTTACAGATGGTGTAATGGTTGCCCGTGGAGATTTGGGTGTTGAAATGCCAATGGAGGAAGTTCCGGTTTTACAGAAAATGATTGCTCAGAAATGTAATAAAGCATCAAAACCTGTAATTGTAGCTACGCAGATGTTAGAGAGTATGATTACTACTCCGCGTCCTACCAGAGCTGAAGTGAATGATGTTGCAAACTCTGTGTTAGACGGTGCAGATGCAGTGATGTTGAGCGGTGAGACTTCTGTAGGTGAGTTTCCATTAATCGTTATTGAGACGATGAGCAAAATCATCAACCATGTTGAAAATACTTCTTATCCGTATTACAAAAACAAAGAATTAGACGAGAGCTGTCCAACTTATATGGCTGATGCGGTTTGTAGTTCTGCCGTATTTTTAGCAGATAAAACCAATGCAGAAGGTATTGTTGCGATGACATCTTCTGGATATACAGCTTTCCAAATCTGTAGTCACAGACCAAAAGCAGGTACTTATATTTTTACATCAAACCGTAATTTGTTAAATACCCTAAGTTTACTTTGGGGAGTAAGAGGTTTTTACTACGATAAGTTTGATAGTACAGACACCACCATTAGCGAGGTTAACAAAATCTTAAAAGCAGAGAAGTTAATTGAGTCTGGCGATATCATCATCAACACAGCGTCTATCCCGATTGAGAAAAAAGGAAAAACGAATATGATTAAAGTGAATGTTATTGATTAATAAATTAGCGTTTATATAAAGAGAAACCCAGCCGAAAAGCTGGGTTTTTTGTTTAAAATATTATGATTATTTTTAAACAGAAGCTAAAATAAGCTTCTAAAAGTGTATCTGATTTTAGAAATTGGAGTTATTTTTTTAATGAAAAAAAATAATTTTATAATTGTTTACTTTAAAAAGAAAAACATCATACTGCTGCTACTATTGTTAAACTAGATCCTTTTTAATAAAAATCTATCGTTTTATTAAGATAAAGATGATGAACTGTTATTTTCCAAAACTTAAAAAGCATATACTTTATGAAAAATCTAATTGCCTATTTCGCTGTGTTTTACACAATAATTTTGTCTAGTTGTGAGAAGTCTGATAACCTTAAAGACAATTGCTACCAAGCAAAAGTACTTAATAAATCTACTGGTTGCGGTGGGGTTATCCAAGTTATGAAAGGGAGTCCCAGTTTACCAAATTCTAAATGGATTGGGGACGAAGGTATAAAATATCAAAATTCTTATGCAGTCAGGAGTTTACCAAGTGATTATACTGTAGGCAAAATAATCTATTTGAAGGTTAACGATGTAATAAAAACACCTGACGACCAAATTTTACCAACAATTTGTGGTCCTTTGCCTGAATATTCACTAGATATAGATCTAGTTGATGCTAACTGCGTAATTATAGAAGATTCTGAGGCGCTTTGAAATAAATTATACTACTTTATCATCAACACAGCGTCTATCCCGATTGAGAAAAAAGGAAAAACGAATATGATTAAAGTGAATGTTATTGATTAATAACCGATAAAATAGAAAGAGGCTATTTCAAAAATTATATTTGAGATAGCCTCTTTTTTTATGTTAGTACGTTGTGATAGTTTTATCAAAATTTAAGCTAAAATCTTTTTTTTCTTCTGACTTAAGTTTAGACTAAGAAATTGCACTTGGTCTGATTTGAAATTCTTTGAAAAAGGCTCTTGAAAAGGATTGCGGGGTGTTATACCCATATTTCAAAGCGGCTTCAGTTATACTTATTCTATTTTCTTTGATATCATTAAATGCTCTTTGTAAAACTTGTTTACGATAAAATTTTATGATAGATACGTTAAATAGACTTTGAAAACCTGATGTAAGTTTAAATCTATTTATCCCATACTTTTTGCATAAGTTTTCTACAGAAATATCTTCTAAATCATAAGTGCTTAAATCGCTTTTAATTCCTTGAAGCTTCTTTATATCATCTGCAGAGAAGTATATTTCAGAATTATTTATACAAGAGATAGACTGGAAATAGTAAGCCATTAATTCGTAGGCTTTACACTCCAAATAAACTCTTCTAAAATTTTTAATAAGCCTACAATTTAAAATTTGTTTGATAATAAGGTTTACTTCATTGGTAATATCAAACAATTCGCCAGGTTGTTTACCAGAAAAGAATGCTTTTAAACAAGCTTCTTTTTCTTTTTTTTGAGTTTTATCAAAGAATTTATCTAAACATATATTAAAGGCTTCTTGATCGAATATTAGCGAAGCTACTTCAAAACGCTTTGATTTTTTATACTCTACTACGGATAGTTTACCATCTTCTTGAATAGCATAAATAAAAGATTGATTTTTTTTAAGGTTTACTTCTAAATTACCCTGTAGATGATGAGTTGAGTCTCCAGAAAGCATTAAACTGATTAAAATTTTATCCTGAAAATACTGACTGTATCTCATTTGATAAGTTTCTTCAGGTTTTCCAGCATAATAGGCTAATAAAACTCCAGAAGTTAATGGAATTAATGCAGTATGACTTTCGCCTAAAACAGGAGCCTTAAATTTGAGCATATCATCCTCACAATTTAATCTGGTTACCTCATCAAAAGGGTAATCTTTTAATTCTTCTATGAGTATTGGCGTTTCCATATTTAATTAAAATTTCCGGAAGGTTTTTGTTTTAAATATATAGGAAAATTTCAAAAAAATGCGTTTTGGATAAATCAAAATGCGTTTTGGGTAAACATTTCGACTGTGTGCGCTATAATTTTGAGCAAATCAAATTCAACTAAATATGAAAAAAATATTTACGCTATTTATCGTTTGCCTATCTTTTACCAAAATATCTGCACAAACCATTAGGTATGTAAAATCCGTTGCTTCTGGTACTGCCGATGGTAGCAGCTGGGTAAACGCCTCTTCAGATTTGCAAGCCATGATAGACCTCTCTATTGAAAATGATGAGATTTGGGTTGCTTCTGGTACATACCTACCAAGTAGTCTTATAGCGATAAGAGATGCTTCTGACTTTTCAAATCCAGCATCTAATGATAGAGATAAGACTTTTTTGATTAAAAAAAATATCAAACTTTATGGGGGATTTGCTGGTACAGAAACCGCCCTTTCTCAAAGAAATATTAGTAATAACGAAACCATACTGAGTGGAAATTTGGGTGATAACACAAGTGCTACAGATAATTCTTATCATGTGTTGTCTATAGTTACCCCAGTTGGGCAGAGTTTAAATAATTCTTTAGTTGTTGATGGATTTACCATCACAGGAGGTAATGCAAATTCAGGACTTGTTTATAATAATATTTATCCTAGATATTGGGGAGGCGCTTTATTTATTGCGGCTGATGATTTAAACCTTAATAATACACCTACCATAAACAATTGTAAATTTATAGATAATTTTTCAACAGCAGGAGGAGGAGCAATTGCAGTATTGGCCTTTAATCTCGGATCAGAATCAATAGAAATACAAAATTGTAGTTTTATAAATAATAGGTGTAATTACCAAGGCGGAGCACTTTTTTTCTATTATGATGGGGTAAATACTGGTGAATATAAGGCGAATATTTATAATAGCTATTTCGAAGGAAATTCAGTAAATAATTTTTTTCAAGGAGGTACAAATGGGGCAACTGGCGGAGCAATTTGTGGGTATAAATTGGGCGAATTAATTATTAACCGATGTATATTCAAAGATAATAGTACAACTGCTGGCTTTGCATCTACTGGTAATGGAAGTGCTGTAGGGTTATTGTTAGGAGCTAAATCTACCATCATTAATTCTTTGTTTTACGATAATGATAGAGCCGCTGTTTACAATAAAGAATCAGATTTGAACATTATTAACTCAACCTTATATAACACTAACGGGACATTAATTGAGGTTAACTCTGCTAAAAGTATCGCCCTAAATAATAGTATTATTTGGACAGATAATCCTATTCAAAATGCGATTACTAATGTGAATACAGCTCCTTTATCCTCAACTTTGAATAATAGTATTTTAAACAGTACCCATCAGCTGGCTTTTACAACAGCTCCTGTTAATTTAATCAATACAGCTCCACAATTTTTAAATATCAATACCAAAGATTTTAAGGTTGAACCAAACAGTAGCGCAGTTAATGCTGGTAATAATAGCTTGTATAATTTGGTGGCATTTGGTAATATAGATTTATTAGGAAATAACCGGGTTGATAATCAAATTGATATTGGGGCTTATGAGTCACAAGGGACATTGCCTGTTACCTTAGTAAATTTTACACTCAAAAAAGAGTTGAATAGTGTTTTATTGGCTTGGCAAACAGTATCTGAGATTGATGCTAAAACGTATATAATTTCACGTTCTAATGACGGGATAGCGTTTAAGGAATTAGTTAAAATCAATGCTAAAAATTTTCAACAAAATAATTACGTGTATGAAGATGATAAACCAAGTAACGGGATAAATTATTATCGATTAGAGCAGATAGATTTAAATGGCGAAATAAACCTTTTAGGGATAAAGTCTATAAGTTTTGAGTTGTTAACAACTGAAGTAAAAGTTTATCCAAACCCAACTACTAACGAGGTAATATTAAATTTTAATCAAGGAGATTATCAGGTTTTAAGACTTATTAGTAAAAGCGGGCAAATATTAGAAACCATAGCTGTATCGCCTATACAAAATGAAATGCGAGTTTCTTTGACCAAGTACGCTAGTGGAATATATTACCTAAGTTTACAAGGAAAGGGAGAGAATTTTTTTAGTAAAGTGCTAAAAGAGTAGCTTTTATAAGTGAACGTTATTGATTAATAAATTAGCGTTTATATAAAGAAAAACCCAGCCGAAAAGCTGGGTTTTTTTGTTTAAATATGACGTGAATCATGTATAAAGTACACTAAACGTTTTTCGTAATCATTTTTTGCGAATTTGCTAGAAAAAAAGAAAAATTTTAGTTTTCCACACTTGTAAACCTCTTGTTATCAGTGTTTTTCTTAGAAAAATATATCACAGGCAAAATTTATAAATCTGGCTGTGGAAAACTCAGAACTGATTATTTATAAGTAGAAATTAAATTTGATAAAAAACTCCTGTAGTTTTTTTAGCAAATAATCAGAATTAGAAAAATTAAAATATCAGTTATGGGAAAATCATCATCAAACAAGGCGGCTACGCCTACCGGAAAAGGGTTGAAATTTGATCGTTACTTTACAGTCGAAGGAAAAGATGTATATGATCTTTTTACGTATGATAAAAGGTCATCGGTAATCAGAAATCCTTCTGGAGACGCAGTTTTTGAAATGAATGATGTTGAAGTACCAAATACTTGGTCTCAAGTAGCAACTGATATCTTAGCTCAAAAATATTTTAGAAAAGCAGGTGTACCACAAGCAGATGGTTCTTTAGGATCAGAAAAAAGCATTAAGCAAGTGGCACATCGTATGGCAAATTGCTGGAAAGTTTGGGGAGAGCGTTATGGTTATTTCGCTTCTGCTAAAGATGCGCAAATATTTTATGATGAAATTGTTTACACCATTGTTGGGCAATTAGCTGCACCAAACTCGCCACAATGGTTTAATACCGGTTTACACAGTTCTTATGGTATTACAGGTGGTCCTCAAGGTCACTATTATGTAGATCCAAAAACAGAAAAATTAGAAAAATCAACCTCAGCTTATGAGCGCCCACAACCACATGCTTGTTTTATCTTATCTGTAGAAGATGATTTGGTAAACGAAGGTGGTATTATGGATTTATGGGTTCGTGAGGCTCGTATTTTCAAATACGGTTCTGGGGTAGGCACAAACTTTTCCAGAATTAGAGGCGAGAACGAAAAATTATCTGGTGGAGGTTACTCTTCTGGTTTAATGTCTTTCTTAAAAATAGGTGACAGAGCAGCTGGTGCTATAAAATCTGGTGGTACTACCAGAAGAGCGGCTAAAATGGTTTGTTTAGACCTAGACCATCCGGAAATTGAAGGCTTTGTTAACTGGAAAGTAGAAGAAGAGAAAAAAGTTGCTGCTTTAATAGCTGCGGGTTATTCTTCAGATTACGAAGGAGAGGCCTACAGAACCGTAGCAGGACAAAACTCTAACAACTCGGTACGTATTCCTAACGAGTTCTTTAGGACGCTTGAAAACGGCACTGGTTGGAATTTAACTGCTCGTTCTGATGGCAGGGTTATGAAAACCATTGATGCTAAGAAGTTATGGGATGATATCGCTTTTGCAGCTTGGGCTTGTGCAGACCCTGGTGTACAGTATGATACAACCATTAACGAATGGCATACTTGCCCTGCTGGTGGTCGTATCAATGCTTCTAACCCATGTTCAGAATACATGTTCTTAGATAATACTGCTTGTAACTTAGCATCTATCAACTTACGTCATTTCTTTGATTTAAAAACGTTAGTTTTTGATGTAAAAGGTTTTGAACATGCTTGCCGTATTTGGACAACAGTATTAGAAATTTCTGTATTGATGGCTCAGTTCCCTTCTAAAGAGGTAGCTCAATTATCATACGATTACAGAACTTTAGGATTGGGATATGCCAATTTAGGTTCTATGTTAATGGTTGCTGGTATCCCTTACGATAGCGATAAAGCAAGAGCATTGGGTGGTGCTATCACAGCAATTATGACGGGTACTGCTTATGCAACATCTGCAGAGATGGCCAAAGAGTTAGGTACTTTTAGCAGATATAAAGAAAATAAAGATAGCATGTTAAGAGTAATGCGTAACCACCGTTATGCAGCTTATAATGCTACAGATGCTTACGAAGGCTTAGAAATTGCGCCTCCAGGAATTGATCAAAAAGTATGTCCTGATTATTTATTATCAGCAGCTTGCAATGCTTGGGATAAAGCAGTAGAAATGGGCGAAAAATACGGTTACCGTAACGCACAAACTACGGTAATTGCACCAACCGGAACTATTGGTTTGGTTATGGATTGCGATACTACTGGTATTGAGCCTGATTTTGCATTAGTGAAATTCAAGAAATTATCTGGTGGTGGTTATTTCAAAATCATCAATCAGGCTGTTCCTGCGGCTTTAAGAAACTTAAAATATAGCGAAGCAGAAATTGAAGCTATTGTAAATTATGCTAAAGGTGCCGCTAGTATTAAAGGTGCGCCACATGTTAACCCTGATTCTTTAAAAGCAAAAGGATTTACAGAGAACGATTTAGAGAAATTAGATAAAGCTATCATCTCTGCTTTTGAAATTAGCTTTGCATTTAACGTTTGGACTTTAGGTGAGGATTGTTTACAACGCCTTGGCTTTAAAGCTGAGCAATATAATGCTCCTGATTTTAATGTGTTAAGATCTTTAGGCTTTAGCCGTCAACAAATTGCAGAGGCTAACGAATACATTTGCGGAACCATGACTATTGAAGGTGCGCCTTTCTTAAAAGAAGAGCATTACCCAGTGTTTGATTGCGCAAATAAAAATGGTGCTAAAGGCGTAAGATATATCCATGCACATGGTCATATTAAAATGATGGCTGCTGCACAACCTTTCTTATCTGGAGCAATTTCTAAGACAATCAATTTACCAAACGAAGCACAGGTAGACGAGATTAAAGATTGCTATGAGTTATCATGGGCATTAGGCTTAAAAGCAAATGCGCTTTACCGTGATGGTTGTAAACTATCTCAGCCGCTATCTACAAAATCTGATGCAAAAGATGATGATAAATTAGAGACTGTAGAAGAAGTTCTAGGCAAAGCCGCAGAATTAAAATTAAGCGATTTAACTCCAGAACAAGTATTAGAAGCAGCAAATGCCATCTTACAACGTTCTGAGGATACGAGCTTTATGAGACAATTGTCTAGAGTTGTACAGAAGAAAGTAATGCCTTCTAAGAGAAGAGGTTTTACCCAAAAAGCTAGTATAGATGGCCAAACCGTTTTCGTACGTACAGGCGAATATACTGATGGTACTTTAGGAGAAATCTTTGTGGATATGCACAAAGAGGGTGCAACTTTCCGTTCTTTGATGAACTGTTTTGCTATAGCCGTGTCAGTAGGTTTACAATACGGAGTACCTTTAGAAGAGTATGTAGAGAAATTCACTTTCACAAGATTTGAGCCTGCAGGTATGGTGAGTGGTCATGAGAACATTAAATCTGCAACATCAATTATTGATTACATGTTCAGAATGTTAGGTTATGAATATTTAAACCGTACAGATTTAGTTCATGTGATAACAGAGCAAAAAGCTGTAACAGGAAACCCACAATTAGAAGATACAGATGTAAATACTGATGCTACAAATGTTTATACGCCAGCACCAGTTCAAGAAACTTTTGCTTCAACAGCTAAGAAAGGTTTATCATTAGATATTTCTATGGGTGCACAATCTGATGCTCCTGCTTGCAGCAGCTGCGGACATACTACCATTAGATCTGGTACTTGCTACAAATGCTTAAATTGCGGAACTTCTATGGGATGTTCTTAGTTTAGAAATAAAATAAAATTTAAAAGCCCTGCAAATCATCATTTGTAGGGCTTTTTTATGTTTTAATAGGCTATTTAAGTTTTTAACTTGCACCAAAGGCCTAAAACCACCAGGCCTAAGAAAATCATAGCCAGTAGGATTCCGGTAAAACTCCCTTTTCTTTCTACTTCTTTTTCTAATGTTTTAGTTGTGCTTTTCTTTAACAATTCTTGTTCTTGCTGTTGGGCTTTAACCGTACTGCTTTGCTGTTGATGGCTTTGTTTTACTAAACTGTCTTTGCTGCTGCTTTTATAAACTTTTACTTTGATATAGCCCGGTTGCTGCTGCAAGCCACTATCTGGATGCCAATAAAAGAGTTCGTCCATTTCTAAGACCATACCTTCTTTCACTTGCTGGAGTGTGGCGTTTATCGTACTGCTTTTACTTTGCAGGCTATCTTTTAAAAATGTAGCCTGTTTGGTTTTTTCCAATGCGGTGATGAGCTGCTGATACCTGGACTTTTGACTCGAACAGGCTGTTAACAACAGTACCATCATAAAGGTGCTTAGCTGCTTCATCTTGTTTCCCTCCTTGCTGTCACCCAATCTGCCACTGCATATAAAGTACGTTTAAGCCTGCGCTTACGGTACACCCCATCACCTTCTCTGCTTCCGGCTTCATTGGTATTCCCTTCAACGGTGATGATGATACTCTCGCCCCAAGCATCTATAAAACCGCAATGGGCAATGCGTTTTTTGGAGGCGTACCAAATGCCAAAAACATCTCCTGCCTGTGGCTGTATCTCTTCTTGCTGCCAGCTATTTTTCCAGATGATACGCTCTTGAGGTAATAAAGCAGGGCTCCATGCGCTACGTGGATTGCTGATACCTGCTTTGCCCAAACACCAGCTTACAAAGGCGGCACACCAAGGATCACCTTTTTTATTACCGGTATAATGCAGATAGGTTTCTACCCGGTGGCCATCATTCCTATTACGCTGTTCACGTACTCCTACTTCCTGGTTATAAAGTGATTGGAGTAAGATCCGCCTCTCTTTTTCTGAATCCTTTTTTGGTAGTGACCCCTTTGCCGAAAGCTCAGTTAATGGGCTTTGCAGACCTAAAATATTGCTAGCAGGCAGCCGATAGCTGCTAATAATAGCAAGGCAAAAGATGCCCAGTACAATACGAATTGTTGCCATAAGCTTAATTGTTTAAAGTGTGGAACCATGTGTTGAAACGGAGGCAAGCCCAGTCTGTTCCAACTGCTATTGAGTAGTCGCCAGTTGAGCAGAAGGAGCAAGATAAATACTAAAAGTGCTATCAGGTGGAGATTCCGATGAAGTTGACCACCCTATTCCGATTTAACTTGACCAGTCATTCCGTTAGAAACTGACCAGTGTATTCCGCTGGAAACTGACCAGGTAAGGACGTTGAAAGATGCTGTAAGATCAAGCCTATTTTTGGGGGATTAACATCTCAGAAATGGCAAATACGACAATCAGCATGAATAAGATAAGACAAATCCTCAGGATGTCCCATCAGGGGCGCAGCATCATGTCCATTACGGTACAGAGCGGTTGTTCCCGTAATACGGTAAGGAAATACATTTCTGCCTTCAATCAGGGAGGCTTTAGCTTTGATGAGGTAAACGCCCTTAATGACAAAGAACTGGAAGACCTTTTTGGAAAGAGCAGGGAGCAGCCCCCTAGTTCTCGTATGCAAGCCCTTCAACGATGTTTCCCTGCTATGGACAAAGAACTCAAGCGTACAGGGGTAAACCGGCAAATGTTATGGGAGGCTTACCTGAAAGAATTCCCCCAAGGCTACCGTTACAGCCAGTTCTGTCTCTATTATAAGCAATGGAAGTCTCGTGTGAACCCGGTAATGCATATGGACCATAAGGCAGGCGATATGCTGTATGTTGATTTTGCCGGCCAGAAGCTGAGTTATGTAAATGAGGAAACCGGCGAAGTGATCCTAGTAGAGGTATTCGTCGCTATCCTTGGCGCCAGCCAGCTCACTTATGTAGAGGCGGTAGCAACCCAGCAGAAAGAGGACTTCATCATGGCCTGTGACCATGCCTTCCATTATATCGGAGGGGTGCCGGGAGCTATTGTGCCGGACAACCTGAAAGCGGCAGTGACCAAGAGCAGCCGTTATGAACCTCTGCTGAACGAGGCCTTTTCAGATTTTGCCGACCATTATGGCACCACAATATTGCCTGCCAGAGCCTATAAACCCCGCGATAAGGCTTTGGTAGAAGGAGCCGTCAAGATCATCTATTCCCGTGTCTATGCTCCTTTGAGGAAGATGGTTTTCCACTCCATCGAATCCTTGAATGCCGCAATAAAGATAAGCCTGGAAGAACATAACAACCAATTATTGAAAGGTCGTAACTACAGCCGGCGCCTACAGTTTGAAGAGATAGAACGGGGAGCCCTTTCTACCCTCCCTCTGATTCCCTACGAACTCAAAAAACAATGTTACGCTACGGTAATGAAGAACGGCCACGTCTGCCTAGGCATAGACAAACATTATTATAGTGTGCCATACCGCTTTATCGGGAAGAAGATAAAGCTGTTATATTCCAGATCCACAGTAGAGGCTTTCTTCCATTACGAGCGTATAGCGATACATAAACGTATCAAAAGCCCGTACAATTATAGCACCGACAAGGACCACATGGCCACCTCGCACAGGTTTGTGGCAGAATGGACACCGGAGAAGTTTCTGGGCTGGGCCTCCTCCATCCATGAGGATGTAAGGCTATATATCCTAAAAATACTGGAACGTAAACAACATCCCGAACAAGCTTATAAATCCTGTGTAGGAATACTCAGCTTTTCCAGAAAAGTAGGGAACGAGCGGCTTCAGATGGCCTGCAGAAGGGCGTTGGGCTATGGAATATACAACTATAAGACCATACAATCTATACTAGAAAACAAGATGGACAGCTATCAGGATAATCTTTTTGCGGATGAACTGCCCATGCCCAGCCATGAAAATATTAGGGGAGAAGATTATTATCAATAAACAAATAATATATGAACACCAACACTTTAGAAAAAATGAGGTCGATGAAATTCTTCGGCATGTTCCACGCTTTCAAAAGCAGCCTGGAGAGCGGGCAGACTGATGGTTATACTGGCGATGAGTTATTGGCCCACCTATTGGAAGCCGAATGGGATTACCGGCAGAACAGACGTATAGAACGACAGTTATTGTATGCCCGCTTCCGCTATAAAGCAACCATAGAGGAGATAAAGCACTATATAGAGCGAAATATCGACAGGAACCAGCTGATGCGCCTTGCCGAATGTAGCTTTATCGACCGCAATGAAAACCTGCTGATTACCGGAAGCACCGGTATCGGAAAGAGCTATGTGGCCTCAGCCATTGGACACCAGGCCTGCTTTTCAGGCTATAGAGTACTTTATGCAAGCACTCCTAAATTATTCGCTAAATTGAAGATGGCCAAGGCTGATGGATCCTATAGTAAGGAAATCCTTAAAATAGAAAGGCAACAGTTACTGATACTCGATGACTTTGGTATCCAGCCCTTTGATGCCCAAAACCGGGCAGCACTGATGGAAATCATTGAGGACAGGCATGGGAAATCCTCTATGATCATCACTTCCCAGCTTCCTGTCGGCAAATGGCATGAACTTATCGGTGAGAAAACCATTGCCGATGCAATCCTGGATCGTATCGTACATGATGCGCATAGAATGGAGCTACAGGGGGAATCGATGAGAAAAAAAGAAATCAGGAACCACTAAAAAATCACTCATAAATCTTTAAAATAATTATTACTTTTATCGAAGATCATAAGGCATCTTTCAACCCTCTTCGCCAGCTTAATCACTGGTCAGTTTGCCACGGAATTACATGGTCATTTTCATCGGAATATACAATGATCAGGTTATTCTAAGATGAGAATAGTTAGCATAGCTAAAACCACTTAAGAGTTTGATTTATTAAAAAGTGACCAAATTTTTCGTAGAGGACGTGGGGACAGTCTTGAACCCACGATACGCCAGAGAGGGAAGTATTTTTACGGAAAAGCAGATTTTCTTTGTTTTTATGTAACAAAAAGCTTTATTTCGCGTTTAAATAATTAAGAGTATACTTCGTTCTACCTCATCGGGTACGGACGATACAAATTTCAGAGGGCTAAGTGTTGGACGCACTTAGCTCTTTATTTTATATCGTTACCTCTTATTTTTGTTATCTTTTCATTCTATTTTTTTATTAATTAAACAAATTTACTAAAATTATTAGCTTTAATAAAAGCTAGTTTTCAACATCCTAACTTTTATGTAACTCTTTTAATTCTTCAAAATAATTGTACAATGCATTTATTGTAAAGTGGGGGTTTCGCTTGTAAGCAGGAAATCCCTCATGCTGCTGTTTATTTAAAATTGTCGCCCTTTCCAAGGCTAATTCTAACCTATTTTTTAATTCTTTAAAAGCATTAGTTTTGGTCTTATGATAATTGGGCATGAACTTTTTTAGATACTTTAGCGCCTCTTCTGCATTTATGAAAGCTTTCCCACAGTTTTCGAAATGCAGGATAAACCAGTGTTCGATACACATTGCGCTATAAGCGTAATGGAAACCTTGCTTTTCTATCATTTCAAAAGCTTCTTTTAACTGAGGTTTATTGTCGTGATCAAAAAAAGCCATACATCGTCATATGAATTTCGGTCTTTCTTTGCAGCAGCAGACTTTTTGATAGCTTCTAAAACAAGACTTTTGGGATCTTGTTGTTTAGCCTGACTTACATTAATTGATACAGAACGTTGCAATGCTCTTGGCAATTCCATTTGCATAGAACGGGCATAGAGATATTCGGTTATCCCTTCGCATAATATCAATATCTGCTTATTAGCCTTCAACTTCCTCCTCCTGCTGCATAGCGATTAAGAAATCAACATCATTAATAATTGGAGTAGCACCAAATCTGCCTGAAACATACCATTTATCCAATGGTGTGTTTAAACGAACACCCTCTAAATCTGAACATCTGAATAAAATACTTTCCCCTCTTTCATTTTTTTCGGTAAACCAAACCTGGTCACGTCTAAAAATATCATTGCTTAACTGTGTAATATCATGTGTGGCGAAAATAAGTTGTGCATTGTTTTTATTTAATTCCGGATGATGAAAAAGCTGGATTAAAAAGCGGGTAATGTTTGGATGCAGGTTTTTTTCTAATTCATCTACCACGAGCACACGTCCATACTCTAATGAATCTATAATTAACCCGGCCAAGGCAAAGAGATTTTTTGTACCTGTAGATTCCTGCTTAACTTCAAAAGTGTATTCGCCTACATGCTCTCCATTTTCAAATAATGGATGGGAAGTTTTAATATCATATTTGAAACGCTCCTGTATTCTTCCTTTTACCTCATCGGGAATAGCATTAGGAAATCTGAATTTATTCCAATCTGTTTCCTCTATCGTTACACCCTGAATACCCGTATCCAAAGCACAAATTAAAGCATTGAATCGTTTTGTGAATAATCCATTTTTATCTTCGGCCAGACGCTTTGCGTAGAAATTTTTCAAGTCGTCTTCCATTTCAATATCAAACACCGGATAAGCGTCTAACTGTTCTGCAAAAAATAAATAAGCCTGCATCAAAGCTTCCACATTATTTTCTGCTGCTTTAGATAAAAACAATTGGTTAGGCAACAATAGTTTTTCTATAGTCTTTTTTGCACCCTTATAATAATCCCCGAATTTTATTTCCTTATTTTGTTCTCTATAAAATAACAATGCTTTGGAATTACCTTTATAGAAATATAGCTCTTCCTGTACTATATTTAAGGTATCGTATACAACTTTATAATCATACTTTACTTTTTCCATTAAAAATGAAACCTCTAAAACAACCGGGGCATTTTGACAAGACCTATCTAATAGAAAAGGATCATATAAAAAAATTGATTTCCCTGGTTTAAAGTCAGCAGAATTTAGCACTAAAAACTCCAAAGCTCTTATAGCATTTAAAAAGCCAGACTTACCAGAAGCATTTGCGCCGTATAAAACTGCAGAATTTAAAAGCTTAAATTTAGCATGGTAGTTATTTACAAGGCCTTTAGCAGCTGTTTTGGCTAAATCTATAACTGCTCTTTCCTTGATAGACCTAAAATTAGTAACAGCAAAACTTATAAGCATATATTAAATATTTATAAGGCAAATATAAAAATAAAACAGATATAAGTTAATTTTTTGAATAAAATTTACAAAAAAAATGTTTTTATCATTTTTGTATTATGGCTATGCAGGTTAATAAATGTCTTATTATGGCATAAAAACAATGATCAATCCAAGCAGGCAAAGGCTTCTTGTGTCTAATAAAGCAGAAACTTTGATATTTAGCATGAAATGAAAGAATTTACAAGGCACAAGTATCCACATAGGCTTAGGCTACGTACTTGCGCCATTTTGGCAACTTTTTTTTTCAAGAAAAAAGTGCCTAGGGCTGGCCGCCTATGAGGCCGGAAAGCTTTGAGCGCCATAGCCTATTAGTTCATAACATCTTTGATGATTATAATTATCCGCCTCATGAGCCGGCGGGGCTCGTTCCTTTTGCGGAACCAAAATGAAGCTTTAGCGAATTCATGAATACCTTTAAAAATCAATAAAAACTAATGAATAAAGTCCTGGTCAATCCCGCAGGAGCCTTTACCGCAAAGGCTTTCCCGCAATTCAAAAACAATGATCGCTTTATTGAAGTCAAAAGTAGAAAGTAAAAAGTAAAAAGAACCTAAAATTGGATAGTTTACACTTATTGTATATTCCGATGAAAATGACCATGTAATTCCGTGGCAAACTGACCAGTGATTAAGCTGGCGAAGAGGGTTGAAAGATGCCTTATGATCTTCGATAAAAGTAATAATTATTTTAAAGATTTATGAGTGATTTTTTAGTGGTTCCTGATTTCTTTTTTTTCTCATCGATTCCCCCTGTAGCTCCATTCTATGCGCATCATGTACGATACGATCCAGGATTGCATCGGCAATGGTTTTCTCACCGATAAGTTCATGCCATTTGCCGACAGGAAGCTGGGAAGTGATGATCATAGAGGATTTCCCATGCCTGTCCTCAATGATTTCCATCAGTGCTGCCCGGTTTTGGGCATCAAAGGGCTGGATACCAAAGTCATCGAGTATCAGTAACTGTTGCCTTTCTATTTTAAGGATTTCCTTACTATAGGATCCATCAGCCTTGGCCATCTTCAATTTAGCGAATAATTTAGGAGTGCTTGCATAAAGTACTCTATAGCCTGAAAAGCAGGCCTGGTGTCCAATGGCTGAGGCCACATAGCTCTTTCCGATACCGGTGCTTCCGGTAATCAGCAGGTTTTCATTGCGGTCGATAAAGCTACATTCGGCAAGGCGCATCAGCTGGTTCCTGTCGATATTTCGCTCTATATAGTGCTTTATCTCCTCTATGGTTGCTTTATAGCGGAAGCGGGCATACAATAACTGTCGTTCTATACGTCTGTTCTGCCGGTAATCCCATTCGGCTTCCAATAGGTGGGCCAATAACTCATCGCCAGTATAACCATCAGTCTGCCCGCTCTCCAGGCTGCTTTTGAAAGCGTGGAACATGCCGAAGAATTTCATCGACCTCATTTTTTCTAAAGTGTTGGTGTTCATATATTATTTGTTTATTGATAATAATCTTCTCCCCTAATATTTTCATGGCTGGGCATGGGCAGTTCATCCGCAAAAAGATTATCCTGATAGCTGTCCATCTTGTTTTCTAGTATAGATTGTATGGTCTTATAGTTGTATATTCCATAGCCCAACGCCCTTCTGCAGGCCATCTGAAGCCGCTCGTTCCCTACTTTTCTGGAAAAGCTGAGTATTCCTACACAGGATTTATAAGCTTGTTCGGGATGTTGTTTACGTTCCAGTATTTTTAGGATATATAGCCTTACATCCTCATGGATGGAGGAGGCCCAGCCCAGAAACTTCTCCGGTGTCCATTCTGCCACAAACCTGTGCGAGGTGGCCATGTGGTCCTTGTCGGTGCTATAATTGTACGGGCTTTTGATACGTTTATGTATCGCTATACGCTCGTAATGGAAGAAAGCCTCTACTGTGGATCTGGAATATAACAGCTTTATCTTCTTCCCGATAAAGCGGTATGGCACACTATAATAATGTTTGTCTATGCCTAGGCAGACGTGGCCGTTCTTCATTACCGTAGCGTAACATTGTTTTTTGAGTTCGTAGGGAATCAGAGGGAGGGTAGAAAGGGCTCCCCGTTCTATCTCTTCAAACTGTAGGCGCCGGCTGTAGTTACGACCTTTCAATAATTGGTTGTTATGTTCTTCCAGGCTTATCTTTATTGCGGCATTCAAGGATTCGATGGAGTGGAAAACCATCTTCCTCAAAGGAGCATAGACACGGGAATAGATGATCTTGACGGCTCCTTCTACCAAAGCCTTATCGCGGGGTTTATAGGCTCTGGCAGGCAATATTGTGGTGCCATAATGGTCGGCAAAATCTGAAAAGGCCTCGTTCAGCAGAGGTTCATAACGGCTGCTCTTGGTCACTGCCGCTTTCAGGTTGTCCGGCACAATAGCTCCCGGCACCCCTCCGATATAATGGAAGGCATGGTCACAGGCCATGATGAAGTCCTCTTTCTGCTGGGTTGCTACCGCCTCTACATAAGTGAGCTGGCTGGCGCCAAGGATAGCGACGAATACCTCTACTAGGATCACTTCGCCGGTTTCCTCATTTACATAACTCAGCTTCTGGCCGGCAAAATCAACATACAGCATATCGCCTGCCTTATGGTCCATATGCATTACCGGGTTCACACGAGACTTCCATTGCTTATAATAGAGACAGAACTGGCTGTAACGGTAGCCTTGGGGGAATTCTTTCAGGTAAGCCTCCCATAACATTTGCCGGTTTACCCCTGTACGCTTGAGTTCTTTGTCCATAGCAGGGAAACATCGTTGAAGGGCTTGCATACGAGAACTAGGGGGCTGCTCCCTGCTCTTTCCAAAAAGGTCTTCCAGTTCTTTGTCATTAAGGGCGTTTACCTCATCAAAGCTAAAGCCTCCCTGATTGAAGGCAGAAATGTATTTCCTTACCGTATTACGGGAACAACCGCTCTGTACCGTAATGGACATGATGCTGCGCCCCTGATGGGACATCCTGAGGATTTGTCTTATCTTATTCATGCTGATTGTCGTATTTGCCATTTCTGAGATGTTAATCCCCCAAAAATAGGCTTGATCTTACAGCATCTTTCAACGTCCTTACCTGGTCAGTTTCCAGCGGAATACACTGGTCAGTTTCTAACGGAATGACTGGTCAAGTTAAATCGGAATAGGGTGGTCAACTTCATCGGAATCTCCAGCTGGTATGACTATGGCGATTATGTGTTGAATATCAGTCCGCTTTCCAGTGGCGGGGGTAGTATGTCAGGAGCTAGTTTATCGAATGCGATAGATTTAGGTAGCTACGGAATGGGCGGAGGCTATAATTCAAATGCACAGGATAATAGCCTATCTTGTTTTGGAGATGATTACGGTCAGCCGAATAATGATATTTATTATAAGTTTACTTTGAGTGGGACCTCTAGAGTAAGACTAGACCATTGCGGCAGCTATTTTGATACCTATATGTATTTATTAAATAGCAGTGGACAGGCGATCAGCAGTAGCGATGATGGAGGACTTTGTAATTTCATGGAGGCAAATATAGAGATCACCTTAGGAGCGGGGACTTACTATATAGTTTCCGAAGGCTCGGGTTATCATACAGGTTATATTACGACGAATATAGAGGTAGATCCGCTATCGATAGTTTATCCTAGCGGCCCGCATGTCATACAGGCAGGAGTATCGATGAGTCCTATAGTCCCTACGATAACAGGAGGTCTTCCGGTGTTTAATACCCAAAGTACGAGTACGTATGCAGGAACAGGGTATTATGGTAATTACAATGGACAATCAAACGTATCCAGTTTCTATTATCCCTGCTATACGACATTCGATGCATCCGGTAATATGTACGTAGCAGACTTTTATAACCACAAAGTTAGGAAGATAAGCGCATCAGGAGTAGTAAGTACGCTAGCAGGAAGTGGAATAGCAGGTTATCAGGATGGAGCAGGGTCAACAGCGAGATTTGTATACCCTAGTGGAGTAGCCGTAGATGCCTCGGGGAATGTATATGTTACCGACCGAGACAACCACCGGATTCGTAAGATCACACCATCAGGAGTAGTAAGTACCTTGGCGGGTAGCGGCTCGATAGGGTCAGCCAATGGAACAGGAACAGCAGCGAGCTTTAATACCCCAACAGGATTAACCATAGACCAATCAGGAAACCTATACGTATCCGATTATAGTAATCATAGAATCCGTAAGATCACACCATCAGGCGTTGTAAGTACCTATGCAGGAACGGGGAGCATGGGCTTTAGTAACGGATCAGCCTTAAGTGCAACATTCAGACGACCACATGGCTTGACGATGGATAGCCAAGGCAACCTGTATGTAGCCGACCGAGATAACTATGCGATAAGGAAGATCAGCAATACAGGAGTAGTAAGTACAATAGCAGGAGATGGAACAAGTGGCTATGCTAATGGTATAGGTACAGCTGCCCGCTTTGGCTGGCCTAATGCCGTAGCAATAGACGGTAGTGGTAATTTGTATGTAGCTGATCAGAGCAACCATATGATAAGGAAGATTACTCCGGCAGGTGAGGTAAGTACTTATGGAGGTAGCCAAACCCCGGGTTATTTGAATGGAACTAACCCAGATGTAAGGTTTAATAATCCTTACGGGGTAAGTACAGATAGTAAGGGAAATGTATATGTAGCAGACTACTTCAACCATGTGATACGAAAGATGTCATCAAGTCCATTTACAGTAACGCCAGAATTACCAGCAGGCTTAAGTATCAATGCATCAACAGGAGCTATCAGTGGGACACCGACAGCTATTTCAGCAGCGACGCAGTATACGATTAGTGGTTATGGCACAGCACCCTCCACTTTTACTTTATCAGTTGGAGCAGGCGGAGGTATTTCCCCAAGTCAAGATCAGAACTATATCTTAACGTTGACACCAAGAATAGCAGGTTATACCACAGCAGCAGCAACATATGCCGGAACGTCTGATGCAAACCAAGTGATGGCAGAAGTACAATACTTTGATGGTTTAGGTAGACCGATGCAGACCGTACAGGTTAAGGGCAGTGCCAATGCAGACAAAGACATCGTGGTACCAATAGCTTATGACCAATATGGTAGAGAGAATAAGAAATACCTTCCTTATGCCAGTACAAGCAATAATGGAAGTTATAAAACCAATCCACTTACTAGCCAGCAGAGCTATTACCAGAGCCCACCGGCCGGGGTAGTACAAACCCCAAACCCTTATGCAGAAACGATATTTGAAGCCTCGCCACTGAATAGGGTGCTGGAACAAGGAGCACCGGGAGCAGCTTGGCAGCCTGTAGCAAATAGCCAAGCAGGCCATACCCAGAAGATGGTATATAGCAGCAATGCAGCAAATGAGGTAAGACTATACAACGCAGAAGCCGTAACTACAGTAGGAGAGACGTATAAAAGAACCCTAACAGGCACAGGCTATTATGGCGCCAACCAGTTGTATAAGACGATAAGCAAGGATGAGAACTGGAGTCCAAGCCAAAGCTTTCCACAGGCAGGAACGGTAGAAGAGTATAAGGATAAGGAAGGCAGGGTAGTGTTGAAAAGAACATTCAATGAGAAGAACAATAGTCTGGAAACATTAAGCACTTACTATGTATATGACGATTTAGGTAACTTAAGTTTCGTATTACCTCCGGGAGCAGAACCAGATGCAACGAGTGTACCTAGCCAGACGACGCTGGATAATTACTGTTACCAGTACAGGTATGATGGTAGAAGGAGATTGGTAGAGAAAAGAATCCCGGGAAAAGGCTGGGAGTATATGGTGTATAATAAACTAGATCAGCTGGTGGCAAGGCAGGATGCTAATTTATTAAATGGATATTTAGTAATTTATAATATGAATAGCTCTGCCGCAAACGGATGGATATTTTATAAGTATGATGGTTTAGGAAGAGAAATTTTAACTGGCTTTTACATACCTATAAGCAATATAAATAGAGCTACACTTCAAGTTCAGGTAGATGGACAAAGTGTTTTATGGGAGACTAAAAATAGTAGTATAGCACAAACAGGTTATAGTAATAATGCTTTTCCTCAAAATAGTATTTCTTCATATTTAACTATGAGTTATTATGATGATTACAATCTGCCAGGTGGAAACCCGAGGCCATATGGAGGAGGAAGTACTATGACCAAGGGTTTACTAACAGCTACTAAAGCCAGTTGTGAATCAGGAATGTTATGGACGGTACAATACTATGATGATAAAGGACAAGTGATTAAGACCTATCGTGATTATTTGTATGGAACTTTAGGAGGAAGTAATTATGTAGAGACAGATTATACGTATAGTTTTACGGGAGAGCAAACCTCAAAAACAGAGAAATATCATAAGGTAAATGAAAGTCAAGAGCTAGTCACAATAGCAACAGCCTATACTTATGATCATGTAGGTAGGAGTAAAGAAATTAAGAAGAAAATAAGTAGCCCTAAAGATAGTTATACGGGCAGCCAAATAGTACTTTCAAAAAATAATTATAATGAGCTTGGCCAGCTAAGAACTAAAGGAATGCATTCAGAAGATCAAGGGCAAAACTTTATCCACAATACCCAGTACAGTTATAACGAAAGAGGCTGGCTAAAGCAAATCAGTTCACCCACTTTTACAGAGACCTTGGCCTATCAAGATGATATACAGAGTGTAGCAACGGCTAATTATAACGGAAACATCTCTGAGATCAGGATGAGTAGCGAAAAGACAGGAGCCAATACCAACTATTTTGCCTATGATAAGTTGAATAGACTGAATAATTCTTGGAATACGTTACTACCCACAATGAATGAGACGAATATCTCTTATGATAAAGGAGGGAATATTCTTCATTTGGAAAGAGGAAACAATACCAATATGAATTATGACTACACAGGTAATTTTTTAAATAGGATAACAGGAACACAAAAAGGCATTTCCATAGATAAATATTATTACGAAGATTATAATGGTAATACTCATTATTTTGAAGATAATTACGGTGCTGATCCTAAATCTGTCTATTATGACCATAACAATCTTCCTGTTTATATGACGGGTTCATCGGAAGCGTATCACCTTTATGACGCAAATGGAGTAAAACTATATAGTTATATATTTGGGTTATATTCAGAAGACTATACCGTATATGCAGGCTCTATAGTCTTTAAAAATTATGAGAATAATATCAGCTTTTTAAGTACGGAAGAGGGAAGGGCTGTAAGGAATCTAGATGGAAGTTACCGTTATGAATACTTTATAAAGGATCATTTAGGTAACACGCGTCAATCTATTGATAAATATAACAATACTGCCAGAGTAATACAGGAGGATAATTATTGTGCTTTCGGTTTATCAGTAAATAAATATAATTTTTCATCGGATAATAAATACCTTTATAATGGTAAAGAGAAAGTCTTTATGGAGGATTTGCAGGATAATTCTTATAATAATTTGGAATGGTATGATTACGGGGCAAGGTTCTATGATCCGGTGATTGGGAGGTGGAATGTGGTAGATCCTTTGTCGGAACAAGCTCCGAATTGGACACCATATCGATACGGGTTTAATAACCCAATCAGATATACTGATCCGACGGGAATGTTTGAACGAGAAGATATTGAAGTTGAAAAGCAAAAAAATGGAACATACAAAGTTGTTGGAGGAGAGGCTAATAATGATAGGAATATTTATGTAACAGAAAATGGCAAACGTACCGGAGAAGTCATTGGCGAAATGCTTACGGAATATTCTTTCCACCACGAAGATGGTAGTGCCGTAATTGGTGCAAATATTAATCTCAATGATAAATCCGGACAAAACTTTATGGATAATGAAATCAAGAATATAGGATTGGTTGATTATATATCAAATGCCCAAGGCAAAGAGCCTCTTGATTTTAAACATCGAGGAATGCCAAAAGGTGCGACTCCAGAAGAGCAGGGACATCATCATTATCGAGGGATGTCTTTTAACGGTAAAGTAGCATCAGCAAGGGATATAGGAAACTATGCAGCAGGTTATGTTTCAGGTAAACACGGTTTTGACTGGGGATCTTCCCGATTTACATTTGATGCTTTGCAAACCAAACAAGAAAAAGGAACTTGGAATACGATTCTTTATTATCCGTTTAATAGAGTTAGAGAAGGACAGCCAACTCAACAAGCAGAACGATCTGGTCATAACACAGGTTATTCTATTTTTAAACAACGACAATTTGAAAGACAATGGCAAAAAGCAACAACGCCATTACCAATAGGACTAAAATGGTAAAGAAATAAAGAAATGTTAGCAACAATCGTATTAGTGCTTATTGTTTTATTAATTATAAGTACCTTTCTATTCAGGGAAAAACATGTTACTTATAAGTATAAAACAGTGGGTAAGACGAAAAAAATATTATTAATAACAGCATTATGTGTTTTTATTTTTGTGATTATAAGTACATTGATGTCAGATGGGATAAGATCTTTTTACTGTCTTTCAGATGATAAATGTGTAACTGTTTGGAAAAGGGAGAATGGAGAGGTTCTGCTAATGTCAGGTAAATATAAAAGCAAAGAAATCCCTTTGGATAATTATATTAAAATAACCAATATGAATTATAGTTCTATAGTAGTTTTGTTTGTAGGTGATAAGTTGCTTGTTGATGTTGAAAATAATGCAATGGCATTACAAAAGTCTTCTAATGGTCTAATAGCATTATACAGAAATAACAAAGCTTTAAACGATAGTCTGTACACTAACTTTGATGGTAAGTATAAACGGTATAAGGAAAAGATTAATTATATTAATATAAATATTGAAGAAAATTACGCTACTGATAAAAATGACAAGAAACTCAACTAACAAAAATAGTGTTTAATAACAAAAATCCTCCTAATATGGTGCAATGAGGGTGAAGGAAAGAGGGTAAATGCTTCTTGTACTTAATAGCCCCTATCGAAGAATACGTATAATGAAATAGGTCAGTTAAAAGATAAAGAAGTACACAGTACAAATGGCAGCGCCCCACTGGTTTAAGTCTTAGCGTTTTGGGCAAAAGGTGTGGAATGACTTAAATCTTATAAACAGAAACAAAACTAAAGTACCAATATAGTGCAATTAGGGTTTAAAAACGGTTAAAAGCTTCTTATACCTAATAGCATATCAAAGAATACCCTCACTGGCGCAAGTCTTAGCGAGTAGGTAAAGCGAGAGAGCCTGACTTGTACCTCATGATTAAAGCACTAAATTTTGTAATGAGTTCAAAATATAAGTTTAACAATCCAGAGGGGATATATTTTGTTTCTTTTGCCGTTATAGGGTGGATAGATGTGTTTAGTAGACAGATTTATAGGGATTTATTTTTAGAGAGTTTAGTTTATTGCAGGAAAGAAAAGAATTTAAATATACACGCATGGGTAATCATGAGTAATCATGTTCATTTAATAATCAGTTGTAAGGCTGGATTTATTCTCTCGGATATAATGAGAGATTTAAAGAAATATACAGCATATAAAATACTGAAGGAAATTAAGGAAAGTACAACAGAAAGCAGAAAAGAGTGGATGCTGTTTTTATTTGCAAAAGCTGGCAAAGAGAATAGTAACCATACAAATTATCAGTTTTGGCGGCAAGATAATCATCCCATAGCATTAGATTTTCATAGCAATATGTTTGAACAAAGATTGGATTATATACATAACAATCCAGTAGAGGCAGGCATAGTAGAGCATGCAGCGGATTATGTTTACAGTAGTGCAAAGGATTATCAAGAAGGTAAAGGTTTAATAGAAATAGATGTATTACAGTGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP043329|3254254:3331404|3293007_3294045_+|WP_149075452.1|DBSCAN-SWA
MFKPDTDVSIYGINIPALFLAVALSYNGVSVFIWAEQEKPDDFPEELIFDHYMGHFLKQFGYQVKDNADMITVSGFLEQSLKLLAGRVCPVVWKSSEKKIGEDFTSTLTLQKISKINPLVYKAEALLLNNNLDLSFRNILLLGWRMSGLINGTLNQKVLLTAELEKTLLQEQWEQKVFKQSAFKRLLAKIHQPKAKVYQLIDAKINLHLSQDRSLEAGELLPDFNFYDEKAQVDIQLHQWTNYKHFSVILFGYLSQPNLFTVSRWVQLNYPVKLYYLPPSERNEPLFEFMGVKPDTKRTFIVRPDLYLGLIHDTIDVEVIDNYLKNVLEMKVNHEKRDASDASIL
>NZ_CP043329|3254254:3331404|3295800_3296373_-|WP_149075454.1|DBSCAN-SWA
MKIGLFFGSYNPIHTGHLVIANYMANHTPLDKVWLVVSPHNPLKDKKDLIQVYDRLEMAKIATEKSENISVSDIELKLPQPSYTIDTLTHLKDIYPEHDFVLIMGADNLKSLKKWKNYELILRDYHIYVYPRPGYVDEELSHHPSVTTTQTPLMEISSTFIRKAIKENKNVQYFLPEEVLEFIESKSLYK
>NZ_CP043329|3254254:3331404|3329893_3330457_+|WP_149075475.1|DBSCAN-SWA
MLATIVLVLIVLLIISTFLFREKHVTYKYKTVGKTKKILLITALCVFIFVIISTLMSDGIRSFYCLSDDKCVTVWKRENGEVLLMSGKYKSKEIPLDNYIKITNMNYSSIVVLFVGDKLLVDVENNAMALQKSSNGLIALYRNNKALNDSLYTNFDGKYKRYKEKINYININIEENYATDKNDKKLN
>NZ_CP043329|3254254:3331404|3289797_3290613_-|WP_149075449.1|DBSCAN-SWA
MIDFLPLFQPLNQALIDFLKQLNEKDWQRATVCKDWTVKDIAAHLLDTSIRRLSLGRDEYQHLQQEFSTYEELLAHINNINKEWVAASKRLSPNILIELISKYQDDLIAYFETLDPFDMALFPVTWAGKSHSENWFDIAREYSERWLHQQQIRFAFNNQELLEPKFYSPYLEIIMEALPYTYQKINAEIGKSVAVEIVGPAGKRWTIKKDKRFWVFDEAHKQADALIYIDQQIAWLLFSKGIHAEEAGQFYQIHGERHLALPVLKMLTVMA
>NZ_CP043329|3254254:3331404|3302193_3303138_-|WP_149075462.1|DBSCAN-SWA
MPVKIPNNLPAIEILKKENIFVINDLRANTQDIRPMRVLILNLMPIKITAETDFVRLLSNNALQVEVTFLRLDSHKSKNTSEQHLELFYKVFTDIKENFYDGMIITGAPVEMLKFEEVTYWKEITTIFDWARKHVTSTLYICWASQAALYHFYGVEKIALDKKLFGVYKHSATEKTNPLFRGFDDEFFIPHSRHTTMRKEDIANKEGVSILSESADAGVAIISSRGGREFYLTGHSEYAPLTLHEEYKRDAKKGLDIAMPENYYVANNPKNPPLVCWTSHANLLFNNWLNYFVYQETPYDLKDVEHLGDIKVNS
>NZ_CP043329|3254254:3331404|3306299_3307730_+|WP_026905279.1|DBSCAN-SWA
MKIVQKRTKIVATLGPATSNKDVLLSLIKAGVDVCRLNFSHGKAEDHQKVIDIIREINQKYKTNVGILADLQGPKIRIGLVKDGGINLINGTQIKITTNECIGDDNQIYITYETFPQDVKAGEIILLDDGKLQMRVVETNRKDTVICEVLHGGILTSRKGVNLPNTKVSIPSLTEEDLVNLDFALANDVEWIGLSFVRKAEDIIDLKRIISRSGKTSRVIAKIEKPEAIDNIDAIIEVTDGVMVARGDLGVEMPMEEVPVLQKMIAQKCNKASKPVIVATQMLESMITTPRPTRAEVNDVANSVLDGADAVMLSGETSVGEFPLIVIETMSKIINHVENTSYPYYKNKELDESCPTYMADAVCSSAVFLADKTNAEGIVAMTSSGYTAFQICSHRPKAGTYIFTSNRNLLNTLSLLWGVRGFYYDKFDSTDTTISEVNKILKAEKLIESGDIIINTASIPIEKKGKTNMIKVNVID
>NZ_CP043329|3254254:3331404|3319725_3320103_-|WP_149075471.1|DBSCAN-SWA
MAFFDHDNKPQLKEAFEMIEKQGFHYAYSAMCIEHWFILHFENCGKAFINAEEALKYLKKFMPNYHKTKTNAFKELKNRLELALERATILNKQQHEGFPAYKRNPHFTINALYNYFEELKELHKS
>NZ_CP043329|3254254:3331404|3283017_3283233_-|WP_039451927.1|DBSCAN-SWA
MAEITIAIKDWDRLKIKLKRKYNHLTDDDLVFAPGKEDDLINHLQERLHRNREYVVFTLKKGLINIENNRL
>NZ_CP043329|3254254:3331404|3309773_3311762_+|WP_149075466.1|DBSCAN-SWA
MKKIFTLFIVCLSFTKISAQTIRYVKSVASGTADGSSWVNASSDLQAMIDLSIENDEIWVASGTYLPSSLIAIRDASDFSNPASNDRDKTFLIKKNIKLYGGFAGTETALSQRNISNNETILSGNLGDNTSATDNSYHVLSIVTPVGQSLNNSLVVDGFTITGGNANSGLVYNNIYPRYWGGALFIAADDLNLNNTPTINNCKFIDNFSTAGGGAIAVLAFNLGSESIEIQNCSFINNRCNYQGGALFFYYDGVNTGEYKANIYNSYFEGNSVNNFFQGGTNGATGGAICGYKLGELIINRCIFKDNSTTAGFASTGNGSAVGLLLGAKSTIINSLFYDNDRAAVYNKESDLNIINSTLYNTNGTLIEVNSAKSIALNNSIIWTDNPIQNAITNVNTAPLSSTLNNSILNSTHQLAFTTAPVNLINTAPQFLNINTKDFKVEPNSSAVNAGNNSLYNLVAFGNIDLLGNNRVDNQIDIGAYESQGTLPVTLVNFTLKKELNSVLLAWQTVSEIDAKTYIISRSNDGIAFKELVKINAKNFQQNNYVYEDDKPSNGINYYRLEQIDLNGEINLLGIKSISFELLTTEVKVYPNPTTNEVILNFNQGDYQVLRLISKSGQILETIAVSPIQNEMRVSLTKYASGIYYLSLQGKGENFFSKVLKE
>NZ_CP043329|3254254:3331404|3254982_3255456_+|WP_039451969.1|DBSCAN-SWA
MGVEQRVRALAEEKIADRPDLFIVEIKVINNTKVIILLDGDNGVGIHDCALVSRHVGYHLEEENLLDHAYNLEVSSPGLDTPLILDRQFAKNIGRNVTVKHLNGDKVEGTLLSADEESITVAHQVKAKGAKTKKAELVESKILKNSIAEVKVSVSFK
>NZ_CP043329|3254254:3331404|3277972_3278209_-|WP_081987637.1|DBSCAN-SWA
MMLSVLLQLSQTGYFMLLAGLFFFPLLVALVTAKDIFFNENLSANLKLVWLLIVILIPLLGAIIYFFWAKPVAARKKF
>NZ_CP043329|3254254:3331404|3292294_3293008_+|WP_149075451.1|DBSCAN-SWA
MTKGTLYLIPVVMAENAVAKSLTPFLVDTINTIDEYIVENEKTARRCLKEAGLKTPQSDLIIHDYGKHSRGGSLKPYFKGLEQGKNVGLMSEAGCPGIADPGAEIIAEAHKRNINVVPLVGPSSLLLALMASGFNGQSFAFQGYLPIDKMARAKKIKDLEGFAERFKQTQLFIETPFRNNPMLEEILRTCRPDTLLCIASNLTAEDEFVKTKSVGDWRKEAPDLHKKPTIFLLYRTK
>NZ_CP043329|3254254:3331404|3315989_3316616_-|WP_149075469.1|DBSCAN-SWA
MATIRIVLGIFCLAIISSYRLPASNILGLQSPLTELSAKGSLPKKDSEKERRILLQSLYNQEVGVREQRNRNDGHRVETYLHYTGNKKGDPWCAAFVSWCLGKAGISNPRSAWSPALLPQERIIWKNSWQQEEIQPQAGDVFGIWYASKKRIAHCGFIDAWGESIIITVEGNTNEAGSREGDGVYRKRRLKRTLYAVADWVTARRETR
>NZ_CP043329|3254254:3331404|3297027_3297891_-|WP_149075455.1|DBSCAN-SWA
MTGYGSATKDLDSGKYTVEIKSLNSKFLELNLKLPKAYSEKEFFLRNECNKQIERGKVMLSINIESNNAGAKAATINQDLLKYYYQELKNTALELGENTNNLLSLAINLPEVVKYDENAVSEEEWNQVLATFQTALENFKKFRADEGEVLEKDLILRIENILTLLQKVEVDEPNRVPVFKERLNTYLADAVGKENIDNNRLEQEIIYYIDKFDITEEKVRLRSHCDYFIKTLKDKDANGKKLGFISQEIGREINTMGSKANDANIQRNVVSMKEELEKIKEQLLNVL
>NZ_CP043329|3254254:3331404|3308026_3308425_+|WP_149075464.1|DBSCAN-SWA
MKNLIAYFAVFYTIILSSCEKSDNLKDNCYQAKVLNKSTGCGGVIQVMKGSPSLPNSKWIGDEGIKYQNSYAVRSLPSDYTVGKIIYLKVNDVIKTPDDQILPTICGPLPEYSLDIDLVDANCVIIEDSEAL
>NZ_CP043329|3254254:3331404|3272056_3274162_+|WP_149075439.1|DBSCAN-SWA
MNDQLFKTPIEYLKGVGPQRAEILKKEAAIFKYEDLLSYYPFRYIDRTQFYKVAEATPDLAHVQILVRLKSFEVIGEKQSKRLIAKAYDDSAEIELVWFQGIRWVEKNLKLNQVYIIFGKLNHFNGKAQMAHPEMELFSKENVTKGNLSLQPVYSSTEKLKQFSLDTKGIQKLTANVLEQLADKIEDVLPHYILQKYKLNSHKEALLHIHFPTDSKSLKRAQTTLKFEELFFIQLKMLRSKLLRTYKFKGNVFSQVGDKFNYFYENLLPFSLTNAQKRVIKEIRSDTQKGIQMNRLVQGDVGSGKTVVALMSMLLAIDNGYQACLMAPTEILATQHYHSLKALLKDDFVEIALLTGSTKKKERKVLFEKLASGDLAILIGTHALIEDTVQFKNLGLVVIDEQHRFGVEQRAKLWRKNVIPPHVLVMTATPIPRTLAMTLYGDLDVSMIDELPAGRKPIETIHLYETQRLRMFGLMKREIALGRQVYMVYPLIQESAKLDLKNLMDGLEVMAREFPLPQYKFSVVHGQLTAKDKEYEMQRFVKGETQIMVATTVIEVGVNVPNASVMIIENAERFGLSQLHQLRGRVGRGAEQSYCVLMSGVKLSKEAKIRLETMVRTNDGFEISEIDLQLRGPGDIEGTQQSGILDLKLADISQDQQILQEARKTVIEIFEEDPDLNLEKHQTLKKFFSVKRNGISLDKIS
>NZ_CP043329|3254254:3331404|3298016_3298712_+|WP_149075456.1|DBSCAN-SWA
MRYLLFFYLCFALLPWSYGQEQFILKGVVFSDLNKQRLPYVNIINQRTQASLKSDEWGVFSIPAQIGDTILIQKEGFQEFSKNISAKQNLVVYLKGVIKLEEVVVTQPSKKADQKEVLDDFRSKGVYFNGSPPLLFSIFHPLTAIHELLSKDANNAQRFVQYISRENAESAVDRKFNKWLIMKHIPIKDEDVAEFMFLYRPKPSQVTYWNDYDVIKYIKDSYEKFKKRESR
>NZ_CP043329|3254254:3331404|3271140_3272064_+|WP_149075438.1|DBSCAN-SWA
MSLKLKCFLAALSANIIWGFVAVPIRFVQNYEAEQILFCRIIASLIICWLFIACFQRKQLRVDINTLTSAPKKERKTLILLLLTSGVLITFNWYAFIYVINHVSLNSAAFAYMICPLITALSGFMILKEDINNQKIVGIMIALISVLILATGSLHEVLWSIITASFYAFYLIVQRVIKAFNKINMLGLQLIIAFIVILPLYLNLGLSLPTNLNFWFDIIIIAVLFTLIPLFLSLFALGGLPSSTVGIIIYINPVIAFGVAFLYFHEGITLIQGFAYLLLVIAVIIFNWKILSGTIRKLATREATDFE
>NZ_CP043329|3254254:3331404|3308650_3309628_-|WP_149075465.1|DBSCAN-SWA
METPILIEELKDYPFDEVTRLNCEDDMLKFKAPVLGESHTALIPLTSGVLLAYYAGKPEETYQMRYSQYFQDKILISLMLSGDSTHHLQGNLEVNLKKNQSFIYAIQEDGKLSVVEYKKSKRFEVASLIFDQEAFNICLDKFFDKTQKKEKEACLKAFFSGKQPGELFDITNEVNLIIKQILNCRLIKNFRRVYLECKAYELMAYYFQSISCINNSEIYFSADDIKKLQGIKSDLSTYDLEDISVENLCKKYGINRFKLTSGFQSLFNVSIIKFYRKQVLQRAFNDIKENRISITEAALKYGYNTPQSFSRAFFKEFQIRPSAIS
>NZ_CP043329|3254254:3331404|3269077_3270523_+|WP_149075437.1|DBSCAN-SWA
MNYSTLKKTVALSLATAFAVAAHAQVTPATTSSSAKTFGGRGQYRTWTFGVNAGGSLPLSIIGGTNDFGKNVEFGEHTMGFYYGISVRKQLAHSFGLQGNLSRGNVIAYNKGVGTFIPGDARAFSTAKTEVQYDINLSGVVNVATVDFLRRENAVNFYVSAGYGLIAFNPTLYTTYAGGDGTPAVNNKGLYGDEGSNDYIRQAYIPVGAGVKFKLSDRVALDFGYDTKFIDGDNFDGVYAGGTSKDKFSVVRGGLEFSLGSKAKPDLNWVNPIAMMYDELKDPTLRQEVEALKGRVTNVEQSVQDLKKDSDGDGVADHLDKCPNTPAGAKVDGAGCELDTDGDGVPDWKDDCPTEKGTAELNGCPEMGSATMSGVDNIQFEYNSSVLRTSAYPTLDKISSALRANKTQGLQLDGHASEEGTDAYNMQLSVDRANAVKTYLVNSGVDAKRISTKGYGESRPIASNATEEGRVKNRRVEFRQK
>NZ_CP043329|3254254:3331404|3260977_3262816_-|WP_149075432.1|DBSCAN-SWA
MKIYFRILSFAKPLSKFAIPYSISTVLYAIFNTIVFSLLIPVLNVLFNQDPTKNLENNQFPEFDFTFEYLSHLFNFYLNQFTVTYGHKGALIFVAAVLVTCVFISNISRYFSQRVIENLRIHTLKNLRKNVFEKVTNLHIHFFNNERKGDIISKITSDVQVVQYSVTNTLQVIVKEPLLIIGYLILLFSISAKLTFFTLLLLPVSGLVIAQIVKRLKAQATEAQSSFGIMVSLVDEAISGMRIIKAFNATGYTQEKFNKENNYYSNINKSIAKRQQLASPVSEFLGVLTLSGILIYGGSLVFENDSNITAAGFITYIGAFSQLLRPAKAISESFSNIYQGIAAGERVLELIDTPSIITDDEDATEIAEFKHAINFEEVDFFYGEKHVLNQLSLQISRGKTIALVGPSGAGKSTLLDLIPRFIDPQKGKISIDGKDIKNITQYSLRNLMGIVNQESILFNDTIANNIIFGRQGFTLEQVEEAAKIANAHEFISKTDKGYQTNVGDRGIKLSGGQKQRICIARAVLGNPPIMLLDEATSSLDTESEKLVQEALIHLMANRTTIIIAHRLSTIQNADEIIVLENGKIIEKGTHQELTQHKGLYKKLINMQEFTNH
>NZ_CP043329|3254254:3331404|3280192_3282955_+|WP_149075442.1|DBSCAN-SWA
MKKFFISIAFTLICLQALAQRQPLTVSGQLKDSTGVTVIGASVKLVSTLDTVLTTSDLDGNFTFRNIKSPVFTLSISALGYKAMTKSYTLERQRGQQVLTLGNIILATDSRQLGEIVVDGTPDVLVKEDTLQYKADRYKLKENALAEDLLKKLPGVEVDREGNVTAQGKAITRVRVNGKDFFGGDVKTATQQIPADLLENVQVIDDYGDRANLTGVRDGEPERILNFTIRPDRNKGYITRGTVGAGNLDRYQASVFAANFNNARQISALANLNNTNANIFSLTQGTGGGGGRGGRGGFGGGNADGLTNIRSLGLNFRDEWSKKVTAYGSYSIASRDNNTFNRSFQQILDANTVVQNLDSGNVDNGNLSHRFDFNIEYKIDSLNYLKITPRFSYATGDEVDISTFSINNDNNLFSNGRINDFSDSRSPNFSTAILFNHRFRKAQRNLALTADISTNSNLRNQETENFNFLAANPNDLEYQRQLIENDNGNDNLRLGFSYNEPLSKTAGLEFNYEYNYNNIKNNRTVLSTQIQNATPLVDEDLSNEYEFQFVTNRFGLNYRVRQAKYNYSIGMGVQPSVLTGNAITLDTTFKTKVVNIFPTGRFNYKFSRTKELTVSYSGRSNQPSYNQLQPVTDNSNPQFPVKGNPELEAEFNNSFNIRFNNFNAESGRTFFTNISYNFTQDKIVTNTVRIQNSAIGALQERQYLNANGFYAINGFYFFSKAFNEKKYTLGLRGSANYNNQVSFINSQRNIARNTVLSQRLQLQIQPKEWLEIVPAASFSYNLNDNTLNERANAKVNTWSFSFDSKIYFTKTFLIGTQADKNLNSGFNSVSVNPFIINAYLEKQFFKGKTGALRLSAFDLLDENVGVSNTVNENIRVERESNRLAQYFMLTFTMRINKFAGRNNLEPEMGEGQRRWRGPSN
>NZ_CP043329|3254254:3331404|3283363_3283951_+|WP_149075443.1|DBSCAN-SWA
MKKILFLSLFAMLCASSSFAQFNLGIKGGLNYSTIKAEDQQFDESGILGYQLGLWSRIGGNFYLQPELYIGSKGADFKFQTAGSTVVQSGEARFTTLDVPLLLGAKIGGDKLNFRLMAGPAFQFNLNTDDDAFSQAINPDFYRYRDFVTNLQAGAGVDIGNLSVDLRYETSLQDINKNDGLSQSLLHLSLGFKIF
>NZ_CP043329|3254254:3331404|3303247_3303976_-|WP_052177047.1|DBSCAN-SWA
MPLSRIYKLHLSPDRKYVKALKNLLGFVPGNLSLYKMAFRHRSIALGIKRGGKNSNERLEFLGDAILGAVVAEVLFKMYPYKEEGFLTEMRSKIVSRVNLNQLGKKLGFNELIEFDPTTVNITSKQSSLLGDAFEALIGAVYLDKGYNFTKDFLIQRIIKPHIDIHTLEQTETNFKSKLIEWCQRHSKDIVFELVPNQEGDNAKLFSIQVLIDNEPMATGIDFNKKSAEKLAAEKTCELLAI
>NZ_CP043329|3254254:3331404|3254254_3254596_-|WP_026905325.1|holin|DBSCAN-SWA
MSLIIEILLMGLAVAIAAFLIPGVSVDGYLSAVLAGILIALANATIGFILRIFTFPINFLTLGLMSFIITVLMVLLVDEVMTSFNTSGFLSALLFALVLAVIKMVFGGFKKDD
>NZ_CP043329|3254254:3331404|3285210_3286371_-|WP_149075445.1|DBSCAN-SWA
MLNFEFKNPTKILFGKGQIANLSKEIPADAKILMVYGGGSIKSNGVYEQVTQALKGFEIIEFGGVPANPEYAILLEALAIIKKENINYILAVGGGSVIDGVKFLASAALYEGEEPWHILAHGIRTEVALPFGTVLTLPATGSEMNSGSVISRAETKEKLAMGGPGLFPAFSILDPEVIKSIPQRQIANGITDAYTHVLEQYMTYPIGACLQDRFAESIMQTLIEVAPKVMANPADYTAAADFMWCCTMALNGLIQKGVPTDWAVHAIGHELTALYGIDHARTLAIIAPSHYRYHLAQKKEKLAQYAERVWNIQEGSVEEKATQAIAKTEEFFHSLDIKTKLSEYTETYEGTAESIEERFNTRGWKALGEHKSITPADVAKIVSMSY
>NZ_CP043329|3254254:3331404|3300834_3301986_+|WP_149075461.1|protease|DBSCAN-SWA
MGATTGNPPYVVTSMLKSVQMPIISNIDANNLNGSSINVTSNMLAFYQSGSGAAPGDSGGPAIINVNNKPILIGASSWGLLPKDQKPTIYTRIKNYANWINLNTGVNFSHYSVSGPSQFCTTTTYQIPNLPSGATVTWNATGSISISGSNTANPVNMSKSIDGTGALTATVNTACGSFNLSKMINVGAPTLGMPSFTNLDNQNPYWCSNNSGNSFTIESNDLSSTYEARLLAYPSLNVYATNSNAYPGFDVFGYVPPGYYVFQLRATNACGTSAWVETEVESVYCTSDWESNNLNVYPNPAKETLTITYENTEGMQAFELSKTASEEKHLLLFDDKGKEVKKDMMKAGDTKLEWDIKNLPSGRYFLHIKEDKEVIKKQIIIKH
>NZ_CP043329|3254254:3331404|3295177_3295771_-|WP_039452018.1|tRNA|DBSCAN-SWA
MFKLQLPTDPFWVKNVVESNIEEILTDHAYCEQKAATNAITLIIQNPNVPELVQEMAELVKEEMDHFKRVHEIIIKRGYTFGKERKDNYVNELLKFLKKGGGENQRTENMVDRLLLAAMIEARSCERFKVLSEHVADNELAAFYHELMISEATHYTLFIGLARKYGKGIDVEKRWQEWLDYEGVIIKSYGKSETIHG
>NZ_CP043329|3254254:3331404|3284003_3285209_-|WP_149075444.1|DBSCAN-SWA
MNKNLEKLFKIAQKEERIILGLMSGTSLDGLDIALCKFKGAGLGTRVEILHFETYPYESSFKEAIKQVFSKKTVDLELLCLLNAQIARQHAEIINHTLKKWAYTATDIDAIASHGQTVYHAPKIKHQLNNYPDATLQIGDGDHLAHLTGIITLSDFRQKSIAAGGEGAPLAVYGDYLLFADEEIDRILLNIGGIANFTYLPAKRKSENIFSTDVGPGNTILDHFMMQKFNLYFDEDAKYAKKGSLNHDLLEALLADDFFTTPIPKSTGPEHFNLVYLNEAQQKSNTIHLKEEDVLATLCEFTALGIAKAIQENISVSGKIEMLMSGGGMHNPLLVERLMHHLPGITFISMQEILGVNPDAKEALLFALLANETLCGQPDDYDFPNQEKLPKISMGKLSFPE
>NZ_CP043329|3254254:3331404|3322337_3323087_-|WP_039454396.1|DBSCAN-SWA
MNTNTLEKMRSMKFFGMFHAFKSSLESGQTDGYTGDELLAHLLEAEWDYRQNRRIERQLLYARFRYKATIEEIKHYIERNIDRNQLMRLAECSFIDRNENLLITGSTGIGKSYVASAIGHQACFSGYRVLYASTPKLFAKLKMAKADGSYSKEILKIERQQLLILDDFGIQPFDAQNRAALMEIIEDRHGKSSMIITSQLPVGKWHELIGEKTIADAILDRIVHDAHRMELQGESMRKKRNQEPLKNHS
>NZ_CP043329|3254254:3331404|3315510_3315993_-|WP_168199458.1|DBSCAN-SWA
MKQLSTFMMVLLLTACSSQKSRYQQLITALEKTKQATFLKDSLQSKSSTINATLQQVKEGMVLEMDELFYWHPDSGLQQQPGYIKVKVYKSSSKDSLVKQSHQQQSSTVKAQQQEQELLKKSTTKTLEKEVERKGSFTGILLAMIFLGLVVLGLWCKLKT
>NZ_CP043329|3254254:3331404|3287729_3288224_+|WP_149075447.1|DBSCAN-SWA
MEQDNTSQSKEKSLYYTGEAKFSPVPLTVSSPVIKPIDKNKLRANAVESMHMQANQQITMLRKQAELIMEQVKDIEERLKISELIYTAEMKFKPVIGQLYHLYQKEDHTFLVSMIAPAEWGRSKTFKKFVSTVKLLADHTWEVLDKSSLNFDDFEEAMPLNQDV
>NZ_CP043329|3254254:3331404|3323098_3324649_-|WP_039454395.1|transposase|DBSCAN-SWA
MANTTISMNKIRQILRMSHQGRSIMSITVQSGCSRNTVRKYISAFNQGGFSFDEVNALNDKELEDLFGKSREQPPSSRMQALQRCFPAMDKELKRTGVNRQMLWEAYLKEFPQGYRYSQFCLYYKQWKSRVNPVMHMDHKAGDMLYVDFAGQKLSYVNEETGEVILVEVFVAILGASQLTYVEAVATQQKEDFIMACDHAFHYIGGVPGAIVPDNLKAAVTKSSRYEPLLNEAFSDFADHYGTTILPARAYKPRDKALVEGAVKIIYSRVYAPLRKMVFHSIESLNAAIKISLEEHNNQLLKGRNYSRRLQFEEIERGALSTLPLIPYELKKQCYATVMKNGHVCLGIDKHYYSVPYRFIGKKIKLLYSRSTVEAFFHYERIAIHKRIKSPYNYSTDKDHMATSHRFVAEWTPEKFLGWASSIHEDVRLYILKILERKQHPEQAYKSCVGILSFSRKVGNERLQMACRRALGYGIYNYKTIQSILENKMDSYQDNLFADELPMPSHENIRGEDYYQ
>NZ_CP043329|3254254:3331404|3316899_3318450_+|WP_039454395.1|transposase|DBSCAN-SWA
MANTTISMNKIRQILRMSHQGRSIMSITVQSGCSRNTVRKYISAFNQGGFSFDEVNALNDKELEDLFGKSREQPPSSRMQALQRCFPAMDKELKRTGVNRQMLWEAYLKEFPQGYRYSQFCLYYKQWKSRVNPVMHMDHKAGDMLYVDFAGQKLSYVNEETGEVILVEVFVAILGASQLTYVEAVATQQKEDFIMACDHAFHYIGGVPGAIVPDNLKAAVTKSSRYEPLLNEAFSDFADHYGTTILPARAYKPRDKALVEGAVKIIYSRVYAPLRKMVFHSIESLNAAIKISLEEHNNQLLKGRNYSRRLQFEEIERGALSTLPLIPYELKKQCYATVMKNGHVCLGIDKHYYSVPYRFIGKKIKLLYSRSTVEAFFHYERIAIHKRIKSPYNYSTDKDHMATSHRFVAEWTPEKFLGWASSIHEDVRLYILKILERKQHPEQAYKSCVGILSFSRKVGNERLQMACRRALGYGIYNYKTIQSILENKMDSYQDNLFADELPMPSHENIRGEDYYQ
>NZ_CP043329|3254254:3331404|3299550_3299922_+|WP_149075458.1|DBSCAN-SWA
MKNYIIILLSIILISCKETNSSFIESDNFNACGVSSFSQLNWAQDLVAGKGACSQIYSGAKLTMYDYMGVKVFYFENLASSTGSCNRILYNCSGMILISANSEQSIWTDFENNKTNGKLIWSI
>NZ_CP043329|3254254:3331404|3289058_3289745_+|WP_039451914.1|DBSCAN-SWA
MKTSRLKISVLGLAFAIGATTILPGCDSLTSTQKGAGIGAAAGGTIGALIGNKAGNTAVGAIIGGALGGTAGAFIGRKMDRQAKELEQSIPGAEVIPAGEGIIVKFDSGLLFEFGKSTLSTAARQNIDNLAASLNKYPDTDIMIIGHTDGIGSDAVNDRLSLERANAVRSYAVSKGVDTGRLKSSGKGKNEPIASNETEEGRTQNRRVEIVIVANEAMKAEAKATTNN
>NZ_CP043329|3254254:3331404|3312118_3315436_+|WP_149075467.1|DBSCAN-SWA
MGKSSSNKAATPTGKGLKFDRYFTVEGKDVYDLFTYDKRSSVIRNPSGDAVFEMNDVEVPNTWSQVATDILAQKYFRKAGVPQADGSLGSEKSIKQVAHRMANCWKVWGERYGYFASAKDAQIFYDEIVYTIVGQLAAPNSPQWFNTGLHSSYGITGGPQGHYYVDPKTEKLEKSTSAYERPQPHACFILSVEDDLVNEGGIMDLWVREARIFKYGSGVGTNFSRIRGENEKLSGGGYSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDLDHPEIEGFVNWKVEEEKKVAALIAAGYSSDYEGEAYRTVAGQNSNNSVRIPNEFFRTLENGTGWNLTARSDGRVMKTIDAKKLWDDIAFAAWACADPGVQYDTTINEWHTCPAGGRINASNPCSEYMFLDNTACNLASINLRHFFDLKTLVFDVKGFEHACRIWTTVLEISVLMAQFPSKEVAQLSYDYRTLGLGYANLGSMLMVAGIPYDSDKARALGGAITAIMTGTAYATSAEMAKELGTFSRYKENKDSMLRVMRNHRYAAYNATDAYEGLEIAPPGIDQKVCPDYLLSAACNAWDKAVEMGEKYGYRNAQTTVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLSGGGYFKIINQAVPAALRNLKYSEAEIEAIVNYAKGAASIKGAPHVNPDSLKAKGFTENDLEKLDKAIISAFEISFAFNVWTLGEDCLQRLGFKAEQYNAPDFNVLRSLGFSRQQIAEANEYICGTMTIEGAPFLKEEHYPVFDCANKNGAKGVRYIHAHGHIKMMAAAQPFLSGAISKTINLPNEAQVDEIKDCYELSWALGLKANALYRDGCKLSQPLSTKSDAKDDDKLETVEEVLGKAAELKLSDLTPEQVLEAANAILQRSEDTSFMRQLSRVVQKKVMPSKRRGFTQKASIDGQTVFVRTGEYTDGTLGEIFVDMHKEGATFRSLMNCFAIAVSVGLQYGVPLEEYVEKFTFTRFEPAGMVSGHENIKSATSIIDYMFRMLGYEYLNRTDLVHVITEQKAVTGNPQLEDTDVNTDATNVYTPAPVQETFASTAKKGLSLDISMGAQSDAPACSSCGHTTIRSGTCYKCLNCGTSMGCS
>NZ_CP043329|3254254:3331404|3324868_3329881_+|WP_149075474.1|DBSCAN-SWA
MSGASLSNAIDLGSYGMGGGYNSNAQDNSLSCFGDDYGQPNNDIYYKFTLSGTSRVRLDHCGSYFDTYMYLLNSSGQAISSSDDGGLCNFMEANIEITLGAGTYYIVSEGSGYHTGYITTNIEVDPLSIVYPSGPHVIQAGVSMSPIVPTITGGLPVFNTQSTSTYAGTGYYGNYNGQSNVSSFYYPCYTTFDASGNMYVADFYNHKVRKISASGVVSTLAGSGIAGYQDGAGSTARFVYPSGVAVDASGNVYVTDRDNHRIRKITPSGVVSTLAGSGSIGSANGTGTAASFNTPTGLTIDQSGNLYVSDYSNHRIRKITPSGVVSTYAGTGSMGFSNGSALSATFRRPHGLTMDSQGNLYVADRDNYAIRKISNTGVVSTIAGDGTSGYANGIGTAARFGWPNAVAIDGSGNLYVADQSNHMIRKITPAGEVSTYGGSQTPGYLNGTNPDVRFNNPYGVSTDSKGNVYVADYFNHVIRKMSSSPFTVTPELPAGLSINASTGAISGTPTAISAATQYTISGYGTAPSTFTLSVGAGGGISPSQDQNYILTLTPRIAGYTTAAATYAGTSDANQVMAEVQYFDGLGRPMQTVQVKGSANADKDIVVPIAYDQYGRENKKYLPYASTSNNGSYKTNPLTSQQSYYQSPPAGVVQTPNPYAETIFEASPLNRVLEQGAPGAAWQPVANSQAGHTQKMVYSSNAANEVRLYNAEAVTTVGETYKRTLTGTGYYGANQLYKTISKDENWSPSQSFPQAGTVEEYKDKEGRVVLKRTFNEKNNSLETLSTYYVYDDLGNLSFVLPPGAEPDATSVPSQTTLDNYCYQYRYDGRRRLVEKRIPGKGWEYMVYNKLDQLVARQDANLLNGYLVIYNMNSSAANGWIFYKYDGLGREILTGFYIPISNINRATLQVQVDGQSVLWETKNSSIAQTGYSNNAFPQNSISSYLTMSYYDDYNLPGGNPRPYGGGSTMTKGLLTATKASCESGMLWTVQYYDDKGQVIKTYRDYLYGTLGGSNYVETDYTYSFTGEQTSKTEKYHKVNESQELVTIATAYTYDHVGRSKEIKKKISSPKDSYTGSQIVLSKNNYNELGQLRTKGMHSEDQGQNFIHNTQYSYNERGWLKQISSPTFTETLAYQDDIQSVATANYNGNISEIRMSSEKTGANTNYFAYDKLNRLNNSWNTLLPTMNETNISYDKGGNILHLERGNNTNMNYDYTGNFLNRITGTQKGISIDKYYYEDYNGNTHYFEDNYGADPKSVYYDHNNLPVYMTGSSEAYHLYDANGVKLYSYIFGLYSEDYTVYAGSIVFKNYENNISFLSTEEGRAVRNLDGSYRYEYFIKDHLGNTRQSIDKYNNTARVIQEDNYCAFGLSVNKYNFSSDNKYLYNGKEKVFMEDLQDNSYNNLEWYDYGARFYDPVIGRWNVVDPLSEQAPNWTPYRYGFNNPIRYTDPTGMFEREDIEVEKQKNGTYKVVGGEANNDRNIYVTENGKRTGEVIGEMLTEYSFHHEDGSAVIGANINLNDKSGQNFMDNEIKNIGLVDYISNAQGKEPLDFKHRGMPKGATPEEQGHHHYRGMSFNGKVASARDIGNYAAGYVSGKHGFDWGSSRFTFDALQTKQEKGTWNTILYYPFNRVREGQPTQQAERSGHNTGYSIFKQRQFERQWQKATTPLPIGLKW
>NZ_CP043329|3254254:3331404|3275485_3277939_+|WP_149075440.1|DBSCAN-SWA
MRIALLISFLLLSGLVSAQSITIKGRVSDGQGAPIPFATVYLKNSTVGTSANSEGEYALKLTTGKKEIIFRAVGYKLLEKSLELSTNLNLNITLESEIYQLKDVVVKAGGEDPAYAIIRKAIKERKKHLKENDAYTAEVYIKGLQKLLKAPKKFLGRDIDKLAKQAGLDSNRTGIVYLSESQSKLSYKAPEYKEEMLSSKVSGSNRAFSFNRASDMNINFYENLQSLGDLSNRPFISPIADNALFYYDYKLLGSSFENGQEINKIQLIPKRGYDPAFKGYIYIIENSWRIYSLDVLMTKESNIKILDSLKISQQYYTVNKNKWMPASVKYEFTGGLLGFRFGGYFIALYSNYNLNPNFKEKEFKEVLKITKEVNQKDTSYWAQVRPVPLTVDEEKDYQKKDSLARKRESKPYLDSLDSVNNKFKWKSFLLMGGYNPRNRFKNEFYSFNSLLGSFSYNTVEGFVMNYEAGYRKKIDTLNNRYLGVSGKLRYGFSNKLFNASMKANIPVLTSATLALGLGSDVVDLNNRGSVKPLYNSISSLFYERNLSKFYQKRFVNASLSGRIIGGLRGQVYSEWANKKWLPNTSSYTIIDKDNRDFTSNNPFMPLADVPLFPAYQSLKIGLGLSYNFSNKYVSYPSGRYYNQTLYPTLALNYTKGMKGVFASDVDYDLIELSLSKNDVKTGFYGSFNFYIGAGKFINNRAVFYPDLKHFRGNQIRVFEETGNTFMFLDYYTHSTSNQYIEGHFEHNFSGFFTNKIPLIRKLRLKELIGVNYLTTSTLQNYHELFVGLQYLNIKAYVGKSFIGNRESQSGLRLAIGL
>NZ_CP043329|3254254:3331404|3286495_3287683_+|WP_149075446.1|DBSCAN-SWA
MVDIILKKAKEKAVLQRHPWVFSGALAQVKGKPQNGDVVKVLDADADFLAYGYYNDQSRVAVRLLDWDENAIINEQWWKAKIEAAIKAREHLQNNDTTTCRLIFSEADYLPGLIVDRFGDYLALQILTSGIEKVKETIVHTLSTLLNIKGIIDKSDASARAHDGLQTQHGTLLWGQLPPEFVEVKENGVKYLINILEGQKSGFYCDQRDNRKIVASYAAGKNVLDCFSYSGGFTLNALLNQAAAVTAVDSSALAVETLKKNIQLNQFDEGKVIAVQSDVNKYLRILKEKGQTFDVVVLDPPKYAPSRSSLDRAARAYKDLNRLGMQVLKKGGLLATFSCSGAMDIETFKQVIAWAALDAGKEVQIIYQFCQPEDHPVRISFSEGEYLKGLFCRIY
>NZ_CP043329|3254254:3331404|3266748_3267645_+|WP_149075435.1|DBSCAN-SWA
MLDKAKKLLASIHSGDVKSLARALTIVENDLAGADDILKSLHPQQTPVIGVTGPPGAGKSTLLNSLLGNLAKKGKRIAILAVDPTSPFSFGSLLGDRIRMKDQFNHPNIFIRSLATRGALGGLSGKTIEMTDVLKAAHFDFIFVETVGVGQSEVEIAGLADLTMVVLVPESGDEIQHIKSGLMEIADVFIVNKSDRPDAQLFTIGLNKLIREKHQQIKVFNTVADKGTGVLELADEILAFKPHAGLKKIELLTQKAWQLIQHYRMRDIQKNKLQQKITEAYHPHFNIYQFIETFMRSS
>NZ_CP043329|3254254:3331404|3318461_3319196_+|WP_149075470.1|DBSCAN-SWA
MNTNTLEKMRSMKFFGMFHAFKSSLESGQTDGYTGDELLAHLLEAEWDYRQNRRIERQLLYARFRYKATIEEIKHYIERNIDRNQLMRLAECSFIDRNENLLITGSTGIGKSYVASAIGHQACFSGYRVLYASTPKLFAKLKMAKADGSYSKEILKIERQQLLILDDFGIQPFDAQNRAALMEIIEDRHGKSSMIITSQLPVGKWHELIGEKTIADAILDRIVHDAHRMELQGESMRKKEIRNH
>NZ_CP043329|3254254:3331404|3265780_3266695_-|WP_149075434.1|DBSCAN-SWA
MAKASIYSLLKEHALEATCFLLIFGLFFSRAVLSISLVLMLLIAIFNFYQHQKPNPIKLKHYFFIGLYILICLSFWNTSDKALWLDILFKNSFLWLLPLVFTFAKTPQEATIRRLVLFFGLCGVLCISVDLGWVLSHQPLYKEIIARGGNIRSVLGPYHTELSLLYSIAFIALWISLLNPSKLYKKWLMIACLCLLAIGLIVVAQRFTISCLLMIALILVCRQAIKTKNHRYIGYFLILFLALIVIYQKVPAIKQKVIFTKNDIDNIIENKNPNYYSISQRWAANKCALEIVKKMFLLVLLLQI
>NZ_CP043329|3254254:3331404|3330849_3331404_+|WP_149075937.1|transposase|DBSCAN-SWA
MSSKYKFNNPEGIYFVSFAVIGWIDVFSRQIYRDLFLESLVYCRKEKNLNIHAWVIMSNHVHLIISCKAGFILSDIMRDLKKYTAYKILKEIKESTTESRKEWMLFLFAKAGKENSNHTNYQFWRQDNHPIALDFHSNMFEQRLDYIHNNPVEAGIVEHAADYVYSSAKDYQEGKGLIEIDVLQ
>NZ_CP043329|3254254:3331404|3300364_3300871_+|WP_149075460.1|protease|DBSCAN-SWA
MKKILFIAVILISIKLNSKAQTTNIVGGTIIDISNVPWQVSLKNISAGNQHFCGGSILSNTWILTAAHCVVGINANNLKVHAGSSNQTNLLEGQYIQASEIKIHPNYNPLTNDNDIALIRLSSPLSFNENVNLIEYANDCNLPDNYLDPGNIASLSGWGLQQVIRLML
>NZ_CP043329|3254254:3331404|3305313_3305550_-|WP_026905281.1|DBSCAN-SWA
MSDIASRVKAIIVEKLGVDENEVTPEASFTNDLGADSLDTVELIMEFEKEFNVAIPDDQAETISTVGQAIAYLEKNVK
>NZ_CP043329|3254254:3331404|3294158_3295160_-|WP_149075453.1|DBSCAN-SWA
MTQKVRWGILSTAKITTDRVLPALKDCNFTQVDAICSRNLVQAQKAATLLGIEKAYGTYEELLNDADIDAIYIPLPNHLHVEWSIKCLEAGKHVLCEKPIGLSSKEAQILLEAAKKYPHLKVMEGFMYRFHPQWIHAKELVNQKWIGDLKVIQSFFSYYNVDPQNIRNQAEIGGGGLMDIGCYCISLSRFLFDAEPLNVASNIDYDPVMKTDIISSGMMQFANGVSSFTCSTQLVPYQRVNIIGDLGRIEIEIPFNAKPLEPAKISLFKADEQKDVFFDITNQYTLQFDAFSKAILDNTNVPTPLEDAVNNMKVIEAMFASDKEKCWKNINGA
>NZ_CP043329|3254254:3331404|3274246_3275449_+|WP_149075936.1|DBSCAN-SWA
MRFFFTIGYQIQAVVLGWYVYNITKDPLSLGLIGLAEAIPSIGIALYGGYVADKSDKAVLIKWVVGLMVLASFALYVVTTPSIVALLGTSKVITAIYSIIFIVGIARGFFSPAAFSLMAQIIPREHYPNSSTWNSSIWQIAAIVGPALGGLLYGFIGVHTTLLIIVASISISFFGTFFFKSVPPTYVRKTSIYESLSEGLKFVFKTKMLVGALSLDLFSVFFGGAVALIPVIASEVLKVGAQEFGMMRAAPALGAVLTMLMMTRFSPMGKPWRNLLFAVAGFGISIIGYGLSRNLYLTLFFLFLEGAFDSVSVIIRSTILQLLTPDEMRGRVSAVNAMFIGSSNEIGQFESGLTAKLMGTVPAVLFGGSMTLVVAAVTWMKTQKLIPKTLHDISKGEENL
>NZ_CP043329|3254254:3331404|3260020_3260971_-|WP_039451961.1|DBSCAN-SWA
MKYFLLLAKRHKKYLKEKKIFRNSTISFYNFWEIEDYNNFWLQKFIVDRNLNPKNKSINFFSVFGPRYVLKKQKAAINIFFSGETMSRFKKYHDYCLPEVDLALGFDDLQHEKYFRLPLWILDFFEPTVDLEKAKEKLKQLNYYKNNKPIVREKFCSLIARHDENGIRKKIVNTLNPIETVDCAGKLFNNTARLQTEFANNKVKFLENYKFNICPENTNQESYTTEKLFESFAAGCIPIYWGSAQKPEPNIFKPSSIIFFDEFKNTLSEDVERLHKDPKLYLDFISQNPFQDTAAEYIIQTISNLELKLKEIINQA
>NZ_CP043329|3254254:3331404|3267628_3268918_-|WP_149075436.1|DBSCAN-SWA
MKYITENADLFVLNRNNLAKQLKKSSLAIFNSNDEYTRSGDQLYKFKQNPDLYYLSGIDQEQTILLLFPDCPNPLYKEVLFLRQTNEHIAIWEGHKYTKEEAQRVSGIKNIYWLDDFWNILSAIIHYADHIYLNTNENDRYANHVPYRDLRFIEDLKSKYPLHHYQRVAPIMRNLRMVKSDTEITITQKACNITGDAFNRVLKFVKPGVMEYEIEAEIIHEFIKQGATGHAYEPIIASGRNACILHYNDNNQPCKDGDVILFDFAAEYANYNADLSRSIPVNGRFTKRQKDVYNAVLHVFKEAKKMLVPGTIWNEYHEEVGKIMTNELIKLGLLDKHDVAKQNPAVPAYKKYFMHGTSHHLGLDVHDISDRYKPFEAGNILTCEPGIYILEENLGIRLENDILVTANGPVDLMAHIPIEAEEIEAMMNA
>NZ_CP043329|3254254:3331404|3299985_3300360_+|WP_168199457.1|DBSCAN-SWA
MVAINIIGAKCKKEDYNERCTSCEKPLFVQTFKNINGEIRKVVNLEYRYNNNQFYILVDAEISLPQIYTNINQKYVKLFSCSASNYTDVDIGKTVQISGNLFNCTTANHGAPTNNLHTFLIYNN
>NZ_CP043329|3254254:3331404|3298923_3299388_+|WP_149075457.1|DBSCAN-SWA
MKNSRLLLFSLIVATLTFSGCDKQETDCGFLSFETVDFRNYPSLGIVNGDEEDKYLVINSKAEFDEKVFISEEDKERFHLDYNKYTLLLGKKRIGGIPGGLISQTWQKECGSTNYIYKVDIKNGGYTALGNFYFGIIVDKVSADEVMFDVNLSE
>NZ_CP043329|3254254:3331404|3320304_3321600_-|WP_149075473.1|DBSCAN-SWA
MLISFAVTNFRSIKERAVIDLAKTAAKGLVNNYHAKFKLLNSAVLYGANASGKSGFLNAIRALEFLVLNSADFKPGKSIFLYDPFLLDRSCQNAPVVLEVSFLMEKVKYDYKVVYDTLNIVQEELYFYKGNSKALLFYREQNKEIKFGDYYKGAKKTIEKLLLPNQLFLSKAAENNVEALMQAYLFFAEQLDAYPVFDIEMEDDLKNFYAKRLAEDKNGLFTKRFNALICALDTGIQGVTIEETDWNKFRFPNAIPDEVKGRIQERFKYDIKTSHPLFENGEHVGEYTFEVKQESTGTKNLFALAGLIIDSLEYGRVLVVDELEKNLHPNITRFLIQLFHHPELNKNNAQLIFATHDITQLSNDIFRRDQVWFTEKNERGESILFRCSDLEGVRLNTPLDKWYVSGRFGATPIINDVDFLIAMQQEEEVEG
>NZ_CP043329|3254254:3331404|3288326_3288992_-|WP_149075448.1|DBSCAN-SWA
MISILGCGWLGMPLGKALVGSGKLVKGSTTKQDKLEEISRQSIVSFLIQLDDLSNEAELMEFLDNEILIINVPPGRNHINADDYPHKLARLNSYINKSKIQKLIFVSSTSVYEENNDVVFEDSFISANASAQRLFLAEEVFRNNPNIQTTVIRMSGLIGPNRHPGRFFGGKTQIPDGLIPVNLIHLDDCIGIIEEVIKQDYWGKTIHAAAPSHPTKKSFTA
>NZ_CP043329|3254254:3331404|3278239_3280003_-|WP_149075441.1|DBSCAN-SWA
MKILIQYLKGYKGLIGLALLFAAINQCFSLIDPHITGKIVDNFINKKDDLTESEFTLGVLKLVGLAVGAAMVSRIAKNFQDYFANIITQKLGAKMYADGLAHSLQLPYQTFEDQRSGETLGILQKVRTDSEKFIIAFINILFTSLVGMVFVIIYSLTVSYKVTLVYFASIPLIFVVSWFLSKKIKTIQKKIVGATTSLAGATTESLRNIELVKSLGLANQEINRLNNTTYKILDLELKKVKYVRSMSFLQGTTVNLVRSSMVVILLLLIFKNDISAGQYFTFLFYSFFLFGPLQEFGNIILTYREAEASLNNFQKTLNTPKEVKPLHPKHTGPIHELELKNLSFQHLTALAPALHNISFSVKKGETIAFVGPSGSGKTTLVKLLVGLYQPQEGEVNYNGIHSNEIDLDELRERIGFVTQDTQLFSGTIRENLLFVSPNATDEACMQVLQKAACQSLLARADAGLNTVIGEGGVKVSGGEKQRLSIARALLRQPDILVFDEATSALDSITEEEITETIRDVSGGKERITILIAHRLSTIMHADRIFVLERGHIVEVGKHEHLLAEKGLYYAMWRQQIGEKRLNDKAFV
>NZ_CP043329|3254254:3331404|3305695_3306112_+|WP_149075463.1|DBSCAN-SWA
MNKKFLKLELDFDFILISITSPLKDYRLCYHINKNLQFEFEKIEDLEITYAGADTKYYSRYLYHVDEFAPAYYLIANKGLGGYLVPELKETDYFVLIKEFIDEEDLSFFLEGLKKIEDIQVAVEVNPRKLKSKENLIF
>NZ_CP043329|3254254:3331404|3290704_3292057_-|WP_149075450.1|DBSCAN-SWA
MNRLKKSLSVLGISILFLILSANTSQAQGRSVSLQTFYDELSYHGDWVNNQEYGYVWRPNVGRDFRPYYTNGRWVMTEYGNTWVSDFEWGWAPFHYGRWFYDSYDGWIWLPDTEWGPAWVEWRTGGGYYGWAPLGPRISVNINIGRRYYPDHYWVFIPQRCIYYPSYQRYWEPRRNVVIIRNTTVINNVYVVNRNVRYNSGPRVEDVRRATRQNVTVYKVNDTNRPSSARIERGTVNVYRPQVEARGDAAPRAIANNSSRPSRTETGTRPSSSNDNRVLDRTENNARPERSSGATGREEINRNAEGRGSSSNNSRPERVERNNAPERPDINNMPSRPNDNSRPERVERPSSSDRPETGNSAPSRPDDNNRPERVERERPSSTPTESRSYPSGDNSRRSSGSERAPSAPQRVERPSAPSSSGKRPSGGSSERGSSSRGSSENSSRSGRPSR
>NZ_CP043329|3254254:3331404|3255486_3256722_+|WP_039451966.1|DBSCAN-SWA
MNSINLIDSFQEFKDFKNIDRPTVISVLEEVFRSMLRKRFGTDENCDVIVNPDNGDLEIWRTRTVMEDGFSEDDDLEIELADAHKIDADLEVGDDFIEQITLESFGRRAILAARQTLVSKILELEKDEIFKNYKDRIGEIVTGEVYQVWKKETLVLDDEGNELILPKTEQIPADYFKKGDTVRAVVLKVEMLNSNPRIIISRTAPAFLQRLFELEVPEIFDGLITIKNIVREPGERAKVAVESYDDRIDPVGACVGMKGSRIHGIVRELKNENIDVINFTNNISLYIQRALSPAKISSIKLDDETMRAAVYLKPDQVSLAIGRGGHNIKLAGKLTGYEIDVYRESSEEDEDVDLEEFSDEIDGWIIDEFRKVGLDTAKSVLALNVNELVKRTDLEEETIEEVLEILRAEFE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026905325.1|3254254_3254596_-|holin	phage holin family protein	NA	NA	NA	NA
WP_039451969.1|3254982_3255456_+	ribosome assembly cofactor RimP	NA	NA	NA	NA
WP_039451966.1|3255486_3256722_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_039451961.1|3260020_3260971_-	hypothetical protein	NA	NA	NA	NA
WP_149075432.1|3260977_3262816_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	5.6e-55	31.3
WP_149075434.1|3265780_3266695_-	hypothetical protein	NA	NA	NA	NA
WP_149075435.1|3266748_3267645_+	methylmalonyl Co-A mutase-associated GTPase MeaB	NA	NA	NA	NA
WP_149075436.1|3267628_3268918_-	M24 family metallopeptidase	NA	NA	NA	NA
WP_149075437.1|3269077_3270523_+	OmpA family protein	NA	NA	NA	NA
WP_149075438.1|3271140_3272064_+	EamA family transporter	NA	NA	NA	NA
WP_149075439.1|3272056_3274162_+	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_149075936.1|3274246_3275449_+	MFS transporter	NA	NA	NA	NA
WP_149075440.1|3275485_3277939_+	carboxypeptidase-like regulatory domain-containing protein	NA	NA	NA	NA
WP_081987637.1|3277972_3278209_-	hypothetical protein	NA	NA	NA	NA
WP_149075441.1|3278239_3280003_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.4e-42	29.1
WP_149075442.1|3280192_3282955_+	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_039451927.1|3283017_3283233_-	hypothetical protein	NA	NA	NA	NA
WP_149075443.1|3283363_3283951_+	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_149075444.1|3284003_3285209_-	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_149075445.1|3285210_3286371_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_149075446.1|3286495_3287683_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_149075447.1|3287729_3288224_+	DUF2452 domain-containing protein	NA	NA	NA	NA
WP_149075448.1|3288326_3288992_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_039451914.1|3289058_3289745_+	OmpA family protein	NA	NA	NA	NA
WP_149075449.1|3289797_3290613_-	maleylpyruvate isomerase family protein	NA	NA	NA	NA
WP_149075450.1|3290704_3292057_-	hypothetical protein	NA	NA	NA	NA
WP_149075451.1|3292294_3293008_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_149075452.1|3293007_3294045_+	hypothetical protein	NA	NA	NA	NA
WP_149075453.1|3294158_3295160_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_039452018.1|3295177_3295771_-|tRNA	tRNA-(ms[2]io[6]A)-hydroxylase	NA	NA	NA	NA
WP_149075454.1|3295800_3296373_-	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_149075455.1|3297027_3297891_-	YicC family protein	NA	NA	NA	NA
WP_149075456.1|3298016_3298712_+	hypothetical protein	NA	NA	NA	NA
WP_149075457.1|3298923_3299388_+	hypothetical protein	NA	NA	NA	NA
WP_149075458.1|3299550_3299922_+	hypothetical protein	NA	NA	NA	NA
WP_168199457.1|3299985_3300360_+	hypothetical protein	NA	NA	NA	NA
WP_149075460.1|3300364_3300871_+|protease	trypsin-like serine protease	G4YAT2	Emiliania_huxleyi_virus	8.2e-09	34.1
WP_149075461.1|3300834_3301986_+|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_149075462.1|3302193_3303138_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_052177047.1|3303247_3303976_-	ribonuclease III	M1HA15	Acanthocystis_turfacea_Chlorella_virus	9.9e-24	33.2
WP_026905281.1|3305313_3305550_-	acyl carrier protein	B2ZXV3	Ralstonia_phage	2.7e-07	38.1
WP_149075463.1|3305695_3306112_+	IPExxxVDY family protein	NA	NA	NA	NA
WP_026905279.1|3306299_3307730_+	pyruvate kinase	NA	NA	NA	NA
WP_149075464.1|3308026_3308425_+	hypothetical protein	NA	NA	NA	NA
WP_149075465.1|3308650_3309628_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149075466.1|3309773_3311762_+	T9SS type A sorting domain-containing protein	NA	NA	NA	NA
WP_149075467.1|3312118_3315436_+	vitamin B12-dependent ribonucleotide reductase	A0A1X9SGV9	Bradyrhizobium_phage	0.0e+00	48.6
WP_168199458.1|3315510_3315993_-	hypothetical protein	NA	NA	NA	NA
WP_149075469.1|3315989_3316616_-	CHAP domain-containing protein	A0A291LH93	Streptomyces_phage	3.2e-10	34.0
WP_039454395.1|3316899_3318450_+|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.5e-82	35.9
WP_149075470.1|3318461_3319196_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	3.5e-45	39.9
WP_149075471.1|3319725_3320103_-	RloB domain-containing protein	NA	NA	NA	NA
WP_149075473.1|3320304_3321600_-	AAA family ATPase	NA	NA	NA	NA
WP_039454396.1|3322337_3323087_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.4e-44	39.7
WP_039454395.1|3323098_3324649_-|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.5e-82	35.9
WP_149075474.1|3324868_3329881_+	hypothetical protein	NA	NA	NA	NA
WP_149075475.1|3329893_3330457_+	hypothetical protein	NA	NA	NA	NA
WP_149075937.1|3330849_3331404_+|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP043329|3386789:3444875|DBSCAN-SWA
AATGAATACACATATATATTCTTTAAACCCAACTTGTACCCAACCCAGAGGTGTAGGCAAATCTGTAAAAGATAAATGGTATGTCTATTTCTATTATACTAATAGCAATGGAATAAGAAAATCCTTTAAAAGTTATAAAGACCTAAACAATAAAAATCAAGATTTAAATCAGCGTAGAAAGTTATTAGCAGAAACCGTAGCAAAATTTGATGAATTGCTGAAAACCAAAAAATTTGATATTGAAACTGGAATATTTATAAAAACAGTATCAGAACAAGTATTAATAAATAATCTAATTGAAGATTACCTAAAATTCAAAAAAGCCATTATAAGCCACTACACCTATTTAAATTATAACTCCTTATTTGAAAGATTCAAACTATCTGCTAAAGGATTAACCCTCTCCCAGATAGACCAACAGTTTATTAAAGACTTTCTGAAGAAAACTCCTGCTAAACCACAATCAAAAAGAAGTTATAGAACCTATGTATCAGGTTTTTTTAATTGGTTAAAAGATGAAAAGGATATTAATATCATTAATCCTACACATGGTTTAAGGTTAGACAGGAATGAACCTGTAGAAAGGCATAAAATCTATTCTAAAGAAGAAATTAAAGCCATTATAGACTACTGTGATGCCAATGGTCATGTTATCCTCAAAACAATTATTTATTTAGTATACGGAGCTCAAATGAGGATTTCAGAGATACTAAGAATTCAGGTAGAAGATATAAATCTGGACTATAATAAAATTGTGCTTCCTAAAGGTAAAGGCAAGATTAAAAATAGGGAAAAGATTGTTCTGCTGGATGAGCCATTAAAAGTTTACCTCTTAAATATGGGACTTGATTTTAAGGATAAGGATAACCAGAAATTATATTTTATTGGTCAAAAGAGAGCTTATGATAAAGCCAAATTTTTTGGAAGATATCCTATTTCTAAAAACACCATTGATACCAGATTTAAACTGCTTAAAAAAGATCTTAATATTAGCCTGCATAAGACGCTTTACAGCTTTAAACATACTGGTAATGTTAATCTTTTGCTAAGTGGAGCAGACCTTATAGAATTGATGTATAAGAACGGACATAAGAAGATATCACAGACAGAAACTTATGCTAGACAGTTGATAGAACAAGTGCCAGAGACTAAATATATTAGGAAAAGTAGGGATGATCTAGATTTTAAGTAATTTAGGACCTAATTTCATTTATGATAAGTAAAATTAAACACCTACTTATATTTTTTTTAGCAGTATTTATTAGCTCTTGTAATCAAAAAAGTAAATCTGAAGAAATAGAGGAACTTGTAATTTTTGGAAATTCTGGCTTCTGTCTAAAAGATAATAACGGGAACTCTTATTCTTCTACTTACTGGATTGATTGTGATTCATGTGATACTAAAGACCTGAAATACGATTCAACTAAACTGGATATAAGGTTATATTTTGAATACAAAAAGGATGATCATACCAAAACTTCTATTAGAAAGCCTGAAAGTACAACTGAATATTACATATTATCAGAACAAGAGACTCAAGGGTTTAAGAGTTTAATTAATTCTACTCTTCTTAGTAATAACCTGAGTTCGATTAATCAAAAAGCTAAGATTTGATTAGAATTAGCATTTTGATATTTAATTGAAGGTTTTTTAGGAAAAAAAGAATAGGCAATTAATGCGGCAATCATGTTGGATATAAAATTTGTAAAAGACCTATGTCTTGAATGCTCAATTTGGCAAATGTTTTTTAGTTCATCGTTTACCGTTTCTATTACTGATCTTTTTCTAAGAGTAATCTTATCATTCATAGTCATTAAGCTGTTTTTCATATTGTTACGAATGCTCGTAATTAGATGTATATCATTGACAAACAATATATTGGCTAGTTTCTCAGAAATATATCCCTTATCTGCGAATAGTTTTCCAAATACTGATTTCAGGAAGTTTTCATTTTTGAGCGGATCTCTGTCATCAACATTTGCCTGTGTAATTGCAAAGTTTAAAATTTCTCCTTTATCGTTGATTACAATGTGGAGCTTAAATCCATAAAACCAGCCCATTGTAGATTTACCTACCTCTGCAATGCCCTTAAATACCTTATTCCGTTTTATTCGCTTATTGTTACATACCCTAACTGGGGTTGAATCTACAAATGAAATACCGCTACAAATACCTAAACAGCAGGTCTTCAAAAATATGGTCATCGGCATAAGTATGCTTTGGCTAAGCTCAACAAAGCGATTATAAGAAACCGTTTTTGGAAATTCGGACTGCATGTGTCGTTGAATATAAAACAGATAAAAGTGCTTAAAGCACCTGAAACCACTAAGATGAAAGAATAGGCAAATCGATATAACCTCACTCTTGGACATCACTGGTGGTCGCTTAGAAGCTTTTCCCAGTAGAAAGGAATGTGTATTGTTATCGAAATCTTTGCAAAATTCATCCACAAGACAAAAAATATCGCTAATTTTAGAGTAGTCAATCATATATAATTATAGTTAAGTATTTGATTTTAAGACACTTAAATATAACTATTTTTATTATGATTGACTAATTTATTTTAAAATATTAATCGAACTCAGGTTAATAAGTACAAAAATAAATATGCTCCCATAAAACCTATAGTTTATGATGGATGGACATATACTTTGTATTTTAAAACTTCTAAGGGAACGGAAAAGGTTATAAACTACATTCCTAACTATTTACCTGATTCCTTAAAAACTTTGCATGACACATTAAGAGAAATAACACTTAAGCAATCTAAGGTAACCTCTGATAGTTTTAAATATCATGAAATTGTTAATGATGAGTCTATAAAACAATATGTTAGTAATCCACCTCCTGTCTTACCTATAAAAGAACAAATTAAGTTCCCACTAGACAAATAGATAGATAAACGTTACAAATTTTAAATTACAATTAGAAATTACCTGGATTTTAAATAATTCAGGTATTTCTATTTACAGGTTATGCTGTATTATGCTTTACTACTTTGATTTGAGATGGTTTAACCTGTTTAAAAGAAAAACCCATGAAATGTAGAGTAGATTTTAATCTCTAATACTTATTATCATTATATATGTAACCATTATCAATACATATTTCCAGAGCTTTTTTGAATACGTGAAATGGATTCGGATTAATATAAACTTCTGATTCAGAAATCTTACCAATAATTATCCCAGTATTATTGACTGCCTTTTTGAAATAGAAAGATAAACTATCAGTTTCCCAATCCTCTTTAACATCATAAACCAGAAAAATCCTCTCTCCAAATTCATTATCCACGCCTATTATTAAATCCTCAGTTATCTTAATATTCTTTCTTATATCTCTTATTTCAATAAAAAAGGGGATAGAGTAGGAAATTAAAAAATAATCATGATTCCAAATTACTTCTCTACTAGTTCCATAGTTAGAACTATAGTTATCACTTAAATCACCAATGATTCTGACAAAATCTTCAATTCTAGGAAAAAACTGACACATTATATTGGTCATGATTAATAGAGGAAAATTGCTAACATGATAGCTTCTTCCCTTTACCTTTATTTCACAATCAGGAATAGAAAAATCAGTAAGCTTTTTCAAGTTCCTAATCCGAAGAATATCTTTATCTATGAATTTATAAGTTAATCTTAAAATATCACTAAAAAAATTGCTATCCTTATTTATCTTTCTATGCTTTGTGTTGCTATTTTCTATGAAAGAACTATCCAGATAATCGGAAATTTTTTCTTTTAAATACTGCTTGTGATTAAAAAAATATGGCTTATAAGAATAAAACTTATCTATATATCCTTCAAAATTTGATTTAGCTCCAAATTTATGATGGAACATATGTTCTATGTTTGGAATATCGCATACAAAAATAACTTTATCAAATCCAAACTTATTGGTATCACTTTTACTGTCATGATGAGCAGTAAAAATATTAAATAACCTAAAGGTGTGATCCGGATCTAACCTATCTAAATCGTCAATTACTAACACAAATTCTTTATTCTCTCTTTTAACCTTTATTCTTTTTAAAAAGTCTTGGATAAGGACAGTAAACTCATCTCGCTCTTTATATGAACCCTTTTTATATTCTATTGAGGTCATAAATTTTAATAACTGTTCTACCTCACCTTCTTCAACATCTTTTTTAAAGCGTTTGAAATCATTAATCAATTCCTTTGTGTCCTTAATAATATCTACTAAACCCTCTATTTTAGGAAAGAACTTACTAAGTGAACTTAGAAATGGAAACAAGTTTAGTTTACTACTCACAAAGCTTTGAGCCAGTAATAAGTTTGAAAAATCATCCTTTTTCAGATCTAGTTCTTCAAAATAATGGTCAATTAAGTAATCAAAAATATCGAACTTTATTAGTTCAAATATATCCTCGTTAGAGGCCACAGAATAATCCACTGGAAATAAAGTTATTTTAAGATATTCTTGACTATTCTCGAAAAATTCGTTTAGGAAATATGATTTTCCACTTCCAAATGGCGCAGTAAATAATACTCTTTTATTATCTTTTAGCTTCAAATGAATATTAAACAGCTCAAGTACTGAAGAATTGTCAACAATTATTTCTTCCATATTAACTTATATCTCTTAACTATTTACTAAAATAAACTTTATAACTTCTACTTCCCCCCTTAACTGAACATTTTACTATTTTACAGTCATTAATTACTAAAAACTAATATTAATGAATTTAGATATAAAAGAAGAAGCCAAACATTTACTAATAACAGAAGAAAAAAAGGGAGTTTTAGAATTAACAATAAAGGATAACTCTAAAAAATTAGGAGAAATACTAAATTTCCTACCTCATGGAATTATTGATAAAACAGTAACTGGAATTGGAGCCACAACTTTAGAAATCTATTCTAAAAGGAATTCCATAATCGTAGTCCCACTAAAAATAATAGCTGCTTCTAAAGTTGAACAACATCCAGAGAACTGTTATTATGTTGGTAGTGCTATAAATAATTTTCAAACATTTGGTGAAGAGGCTTTTGACCTCTTTCTAACAAATGATAAGATTCCCTATAAGAACGTCATAGTAGTTGCAGAAAGCTTACCTAAAGTTATTAAAACCATTGGAGAAGATGTTTACAAGAATTATTTTCTACTAATAGATGAAATTAATACTATTCAGGAAGATTCTAAATTCAGAGAGACTATTGAAAATTGCCTAGATATATATTTAAAATTTCCACCACAATCAAGAGCAATGGTTACTGCCACTATGATTAATTTTTCTCATCCAGAAATTGCTAAAGAACAAAAAACAACTATAAACTATGAGGAACAAAAGCCTAATCTTATAGATGAATTTATAATGTCTTACAACACCCTGGGTGTTTGTATAGATTTAATTGAAAAATTATTAAAAGAACATCAGGATGCTAAAATAGTAATAGCTTACAACTCTGTAATAGGTTCAAAAATACTTGCGGAGGAATTGGTTCTTTCAAATCCAGAAAATGCCAAAAATGTAAGCATTCTTTGTTCTAAATCAAATAAAAAAAAAGCAGGCGTATTTTATGCCGAGCTTACTGGATTAAAATATCCAAGTAAAATAAATTTTATTACCGCAGCTTATTTCTCTGGGTATGATATTGAAGAACAGTACTACTTAATTAACTTAATTGACGAGAATGAAATATTTAGTAAAATATCAATAAATGCAGTTAGACAAATTGCAGGTAGAGCAAGAGAAGGTCTTCATAAACATTATATTGTATATCCATATTCTGAAAATGAAGAAGAATTAATAGAATATGTGGATGAAAAACAACTTTTAGATTTAGCAAAAGTAGAACTTAAATCAATAGAGTGTATCGAGAATAATTTTAAAGAATATCCATTTTTTAAAACTACAATGTTGGACATTCATAGTGCTGTTATTGATAACGGAGGCTATAAAGGTTTTAAGCTTATCAGAAGGAACATTGAAAATGAAATAAACATATCATATTTTAATATTGATTCATATTTAGAACATCAAAAAACACAATATGAAGAACATGCTAGCTATAATTCATTTCTTAAATCGTTATCAAATAGCTTTTCAGTTCTACACGTACTTAATCTACAATCTCACCATGAATTCAGTAAAGTAAAAGAAAGTAATTTGGACGTTGATCAGAGTATTAAAACTGCAATTGAAAATTTACAAAATATTACAACCGATAATGAAGCATATTATTTGTCTGTAAAAGCTGAGGATAATATTCAAAAAAAGGTTTACTTCATTTATGATAAGCTGTCAAAGTTCTACTATGAAAAAGAGACATTATTAGATAAAATAGCGGAAGTAGCGAAGAAAAATTCTAAAGCCTTCAATATATTGAAATCAGAGGTTACACATAAAAGCTTACCCCCTTATCATCCACTTAAAAAATTTATTTTTGAATATTTTAAAGAAGGTGTAATATATAAATCCAGTGAAATTTTAGAGCTTTTAAATAAAGTACATGCTTTAGCCTCTACTAACCATAAGAAAATTGATAGTGAATTAAAGGCTGTAGAAATTTTTAACTGTTATTTTGAAACTGTTAGAAAGAAGTACAATAATGGGTATTTATTGAAAAATTATATTAAACAAGAAGATTATTTAGATACAGTAATAAATAGAGATGAGAATAACATCTTTAGTTACTAAAATATAATATAATAATAAATCTTATGGCATCTACTTTCTATTATAATTTAAAATATAGATGGTAGGTGTCATTTTTATTTTTAGTTTGTGTCTTTCTTTTTGAGCTTGCCTGTACAACTCTCCCCTCCATAACTTCACAGCTTGATATACCCGTCATCTTGCTACAAAAAACTCATTTTATTCACTTTAAAAATTAAATCCAAAAATTATGGTAACAGTAACTAATTATCTGCAAAAAGAAAATGCAGAGGGGAAAGCCTTTTTTATGCTAGAATTAACCGGAGAATTAGAAATTGTAGTTTCTCAAACAACAGGAAAGCCTTATGCTACAGTAAGGAAGGTAAGTATACCAACAACTCTTGATGAAAACATGTGCAAGTTGATGTTGGGAAAACAAATGCCTGGTCAAATAGCAAAAGTTGAAGTAGAAGAAGCATATGACTACACTAATAAAGAAACAGGGGAAGTACTCAGCCTAAATTATAGGTATGAATATTCTGCTACAGAAAAAGCACAGACTATGGAACAAGCTGTTTTTCAAGTATCTTGAAGGTTTAGTATAAGTCAGAACTTAAGATTATAAGGTGATATGTTATAAAAGCGTATCACCTTTTTTATTTAATAATTTTTAGAATTATGGAAATTAGAAAAGCAGAAAGAAAAAGAGCCAAAATTAAAATGGCTTTACAAGGGAGTGCTGGTTCTGGTAAAACATTTAGCGCTTTATTAATAGCTCATGGTATCTCTACTGATTGGTCTAAAATTGTTGTTATTGATTTAGAAAATAATAGTGCTGATCTGTATTCACACTTTGGACACTATAATGTATTACCATTAGAACAACCTTATTCGCCAGAGAAATGTATTCAAGCATTAGAACTATGTGAGCAGGCAGGTATGGAAGTAATCATCATTGATGGTTTAACACCATGTTGGGAATATCTTTTGGATTTACATGCCAATATGAGTGGTAATTCATTTACAAATTGGTCTAAAATTACTCCCAGACAAAATGCTTTGGTAAATAAGATATTATCTATTCAATCTCATGTGATTAGCACCATCAGGGTAAAACAAGACTACGTACTAAATAATAAGGATGGTAAAATAGTTCCTGAAAAAGTAGGGCTTAAAGCCATTCAAAGAGATGGATTAGATTATGAATTCACTATAGTGCTAGACATTGATAATAAACATCATGCAGTAGCTTCTAAAGACAGAACAACCCTATTTATGGGTAAACCTGAATTTACAATTAGCAGAAAAACTGGAGAAGATATTTTAAAATGGTGTAATGAAGGTATTGATGATACTAGCAATATTTTAGAACTCATTAAAAACGCCAATTCCATTGAAGTATTAAAGGATATATATTTCTCCTATCCTGATTATCAAAATAGCCTATCAAAAGCATTTGCTAGTAGAAAAGAAGCACTTAATAAACTTGAACCCTTTAACCAAAAAACTTAATTATGGAACTATTAACAATTAATCCTCCTCCAATATTAAAACAATCTTCACAGAAATCTTTCATTGTTGCAAATACCCTTGCATCTTCTTATCAGGAAATAAGAAATAATCATATTATCCCTGTATTCATTAAAGATAATGAGCCTGTTATATCACATGCAGATTTTATTGATGTTAGTAATGAGATTGTACATCATGTATTCCAAAATGAAACCATTTTAAGCCCTTCTATAAGGTTAAGTCATCCAATTAAAGGCAGAGTTCCAGAAGCTAAAAATAAGCCTGCTAATCAATTATTAGAAGAGGAAAAAACCATTTATTATGAAAGAATGGCTTTTGTTATTGAAGTACCTACCATAAGAGATACAGTTTCAGGAAATCAATTAAACCTGACTATAGGAGGTGTAAAATCTTATAATTTGGATAACCTCTACAGCAAAAAAGGGACAGATGAACATTTCAAAATCTTCATTGGGTTTGAAAATAAAGTATGTACCAATATGTGTGTATGGTCTGATGGCTTTATAGCAGATTTAAAGGTAAGGAGTATACATGAACTTACAGATGCTATTTTAAATCTGATTACCAACTATAATGCAAAACAGCATTTAGATAATCTGAATAAGTTTACCAATTACACTTTAACAGAAAATCAGTTTGCAGAACTAATTGGAAAATGTAGAATGTACAACTATCTACCACAAAATGCTAAACAGGAAATTCAACAGTTACTGTTTGGAGATACCCAAATTAATTCTGTAGCTAAAGACTATTATAATGATAAAAGTTTCTGCAGATCTGCTAATGGAGATATTGATTTATGGAGGTTTTATAACCTTTTAACAGGAGCTAATAAGAGCAGTTATATTGATACTTTTTTAGATAGAGGACTGAATGCTTATGAGTTTACCAATTCTATTGTAAACGCTTTAGAATCGCCCAAAAGTAACTGGTTTTTAAATTAACCCTGTTAAAATGTGAAAGACATTATTTATACCCACAGTCTTTTAGTAGTAGATTCTAAAGGTCAAATTTTCAGAATATTTACTCCATTTTTAGTAATTGAAAAATTAACACAGCAGAAATACTGGGTGTCTAAAATAGTTTGGGATGCTTTTGGACTTCCTTATTTTGAAATAGAGGGAAATCTGGCAATTTATAGCAAATTTAAAATCTAGTGAGCCTTAGTAAATCTACCAATAAACTTGATAAAGTATTTTCTTTATTTTATAACTTATTAGCATTAATATAGCCATTGTTAAAAATTCAGAGATAGAATACAAATGGATTTTATAAATTAGCTGAATAAATAAGGAAGATTATTAAGAGATATTAAATACATATTCGATTAAAATATAAGCGTTAACTAAAAGTTCTTGTAAGAAGAAACCTGAGAAATTTCAAAGTACAAACAAGAGCAGTTAGAATAACGTCTCATGCTAATAAGCGTGGGGCGTAATCTATCTGTTTGTACGGGCTTCTCAGGGCCTCTTCTACAGATCAGGTTATTGTCCTGCGCTTATTGTATTATAAACCGCCGTTGTTGGGACTTCTTTGGCAATAAAAAATCAATTTATTTTTATGAAAAAAGTTTTATTGTTAATGCTTACTGCATCAGCATTACTCGGTGCTTGTAAAAAAGACAAGGATGATTCAAATCCTGCAAATGGCTGTAAAATTGTAAAATTTACACCTTCTGGAGGGCATGATTATGTTAATTCAGAATATTTAATAACTTATAACTCAGATGGTAAAATATCCACGATTACAAATGCTGATGAAACTAGAAGATTTTCCTATGAGTCTAGTAAAATGCTGGTTAGTGTCGATAATCTATTGATTACCTACAATTATAATAGTCCAAACCAGATAAATAGTATTATAACCAATAGTCAGTGGCCAGAGAATGTATCTGTTACTTATGCAGATAACAAAGTTTCTAAAATACTTACATCTGTAGACGACATCTCTTCAACATTTACTTATTCAAGTAATGAAGTAGTTAAAATATTAGAAAAATGGGGAGATACAGATACAGAAGAGGCTTTAATAACCTACAAAGAGGAAAAATATTCAAACCCTTTAATCTTTGAATTGATATTTCCTTCAATGATTGACGGAGATATCAGGAATTTTATTAGATATAATTTATCCAATTCTTTTGGAGCTTCAGAGAAAAGACTAATTGATAAAATAGAATATATAGGCAAAGGAGACCGTAGTTATAATACTCGTACAGATACTTATTCTTATTTAAAAGATGATAAAGGGAATATAATCCAAATCATTATTACTAGCACAAGTTATACCACAAGATCTTTTACCCTTGAATATAGCTGTAATTAAAATCTAATAAATAATGAGAAAAGTAAAAACCCTAATTATAAGAGCGGCTATATTATATGGTATAGCCGCTCTATTTAGTTTGTCATTATCAGTATATAATTGGAATACATTTTCTATATACTTCTTTATTATCCTACTTGGTATGATAGCCACTGACATATTATTTAATTCAAAACATGATTAACAGTTTAGTTATTAACTTAATAATACTGGCTATATGTCTTATTATTAATATAGCCTATTTAAATAGTAAAGTTAACCGAATTCCTAACCACTATATTTTTAAATTAATTGGAAATATTAATACAATAGGAATTTTAATAATTATTATCCTAATTGGTATTAAAGTATCTGTATGGTACGCTATTTTAACATTTGTAATTGCTTTAATAATATCTAGAATAGCACATGTGATTTTTAATGATTCTTTAACTAATTTAAAGCGTCAAATCAATGCAGTTGATCCAAACAGTTCTGAAAAATATAGTTTTATGAGTATTGCTATAATACCAATAAATCTATTTGCTACTTATATTATAATACAAGCTCTTATAAATTTATTTAGAATGTAATGGGAATTATTTATTCATTTACTTGTGGTAAGTGTTCCTACCATAATGAAGAAGTCAAAATCGGAAATTCTAGATTAGGTTGCCATAATGGAGAAGATGATTATGAACTTGGAACATGTTCTGATTGCAAGATAATATTTGGTTATAATTGGCCATATTGTCCTCAATGTGGAGAATGGAAAACTTCTATGAAGTCAAATATTAAATTAGTTTTAAAACTGAAGAGGCCTAAGTATACAGTGAAATTTCATAAAAGCAATGACGTGAAAATAATTCCCTGTCCAAAATGTAACCACGAATATTTAACCCCACATTTAAAATTGTTTTATGATTAATATTAAACCCTATACCACCATAAAAACCATTTTAATAGCTTTATTACTCCTTTGTTTATTAAACCTCCCTTATGGTTTATATCAGCTTTTTAGAGTAATATTTACTATTGGCTTTGTATTATTAGCAATTAAAGCAAATGAGGATAAAAAGCAAACGGAGTTAACAATTTTTATAGTACTGGCAGTATTGTTTCAACCTTTATTAAAGATTCCTTTAGGTAGAGAGATATGGAATATTTTAGATGTTGTTGTTGCTTTAGGATTGATTGTAAACTTATTTAAAACTTCCAAGAATGAAACCAGTTCAAATATTTAAATATTGTGAGCAGGAAGATTATAAACTTCCAGATACAGCAGATATAGATGTAATACCTCTAGAGTGCATTAATTGTATTTTAGATGATATACTTTCTACTTCTGAGAATATTAGAAAAGATTGGATTAAGCTATATAAGGATGGAAATATGCAATTACAATGTAGGTTAACAGGTAAAAAGCACCTTATTACTAAAGAGTTTTTTGATAAAGTAAAATGGGATTAGTACTATGTCCAACTACCAACCATACTACCAAACCCCCTTTATTTTTATTGGTTTATTAGCATTAAATAGCTTAAAAATTTAAAAAATGATTTAGGTTTATAATTGGTTAGTTTAAGCTCAGTTCTCCCCGTTCTGAGCTTAACTGTTTTATAGGGGTTTCTATAACGCAAAAATCAACGCTATTGCCTTTATACTGGATCAAGCGTAAAAGTTGGGGAGGATTACAGATTTGATTATTTTTGTAGAAAATCAATGTTTTGGATTCTACCTTACTATCATTAATCTTACCCGAAGGTCTTAGCGAATACTTTGAACTGGACAAAGTAGAGACTGTATCGGATTCTTATTACATCTATCTTAAAGAAAGGAATATACAACCCAAAGAGTTCACCGCTCAAAAGTTAATTTCTAAGGGTTTTTTCGAAGAGATTTCTGTCAGAGACTTTCCCTTACGCGGAAAACCTTGTTTTTTAAAGCTTAAAAGGCGGAAATGGATGATCGTAGAGACAGGAGAAATCGTATTTAGAGATTGGAATTTGGTAGCAGAAGGGACAAAAATGACTCAGGAGTTTGCCTTTTTTTTTGAGAGACTATTTGGATTCAAGCCCAATAAGCTGTAAAACACTTGGAAGATTCTTTGGAGTTGAGGGTAAACGACTGCAAGAACAGTATGTAAGCCATTTGAGTGACTTTATGAGTTGGGATCAAGCTGAACATGCTCAGGACTGGTTGCTTTTTCCAGACAACCTTGGTGAATATCTATCTATTGATGAGACCAGCCTTTCACAAGGGGAACTATATACCATTGTTACCAATAAAGCAGCAAAAGGCAAAAAAGGTGCTTTGGTTGCTATTGTAAAAGGCACAGAAAGTGAAACGGTTATAAAAGTTCTGTGCCGTATAAAAGAATGGGCGAGAAAAAAGGTAAAAGAGGTCACTCTTGATCTAGCTCCCACCATGGCTAAGATCGTACGAAGGAGCTTTCCAAAAGCAAAGCTTGTCTCCGATAGATTCCATGTGCAACAGCTAGCCAGCGAAGCTGTTCAGGAAATCAGGATAAAACATAGATGGGATGCTATTGAACAGGAAAACAAGGAAATGGATCTTGCTAAAGAAATAAAGAAGCCTTGGATTCCAGAATTATTAGAAAATGGAGATACCTTAAAGCAATTATTGGCAAGGAGCAGGTATTTACTGTTTAAGAAAAGAGGTGAATTGGACATCGTCCCAAAATCATAGAGCAGAACTGTTGTTTAAACGATATCCAGATTTACAGAAAGCCTATGAAATCTCCCAGGAGTTGTCCTCTATATTTAGCCGTTCAAAAGACAGAAGAATAGCTTTCAAAAAGTTGGCAATATGGTATAATAAGATAGAAAAACTAGGTTATAAACCCTTCAATACCATAGCTAGAACCATTCAGAACAATTATGAAACCATATTGAACTATTTTGATAACAGAAGCACAAATGCATCCGCAGAATCTTTCAATGCCAAGATAAAAGCTTTCAGATCGCAGTTCAGAGGCGTAAGAAATGTGAAGTTCTTCCTCTTTAGACTAGCTAAAATATACGCTTAATGTCTCCTCCCCAACTTTTACGCTTGATCCTTTATACTGGTGTTTGTTGTTTTGGAAATATTAGGTTTAAATATCAGCATCATACCATTAATCATACCACCAACATTCCTTCAACATCATTAATTAACCTTCTAAAGAACAAACGAAATGAGTATACAAACATACTCACTCAATCCTTTTTGTACCCATCCAAAAGGAGTTGGTAAATCTGTAAAAGATAAATGGTATGTATATTTTTATTATTCCAAGATTCAAGGAGTAAGAAAACTTTACAGATCTTATACAGATTTAAATAACATGCATCAGCATGCTTACCCAAGTTTATAAAAGAAAAGCATTTCAATAGTAGAAACCGGGTTACATTTGATTTAAATATTAGGATGCTGGTTAATTATTTAATATCTTTAGAGGGTATAGCGATTGTAATGAAACAGCGATCAAAGCCTGTTTTAAATAGTGGTTTATAAAAGAGGCTGTCTCAAATTACCGTTTTGTGTCAGGCTGAGCGGAGTCGAAGCCTTTTCTAAGCATATCAGAGAACATTTCGACTCCGCTCAATGTGACAGATACTATTTTTGAGACAGCCTCTTTTTTGTTTTTACAGCTTTTTTAGCTCAGCTAGTATAATCTCCCGACATTCAGTCAGGAATATAATAAATGGTTTAAACTTTAATAATAAAATTAAAAATAAGTTAAAATAAATTAGATAAATGAAGAAACTTCTACTATTTGGGTTGCTCATAGCCTGCTCATTTAATTTAAAAGCTCAAACGCTTTATGACTTCAATACTACTGGAGATTTGGAAAAATATTTTCAAAAAAGTGGGACAACTACCGGGGTTACGCAAACAACAGGTACAGGTTTAAATGCATCAGGATCAATAAATGTAACTCAAGGAATTAACGAGATTTTTACCACCAAACAGGGTTATAGTAATGGTGGCATTGGTGCTATTTATACCTTCTCTACTTATTTTAAAAGTGAAGGTGTTAATGGATATGGTGGAGTTGGATTTACCAATGCCCCAGGTAGAACAAGAGGAATTTACGCAAACTTAGATATTGGACTTGGTATTTCAGTACATGGCGGTGGCTTTGTTTGGCATAATAATACCACTTCTATTGATGGAATTTGGACTGCAGGCGGTGTAGTAAACTCTACAATTGCAGATTTATTAGGTGCTGGTTCTCCTGATAAATGGTTTAAAGTAATATTGATGATTACCGCTAAAGCAAATAGTGTATTTGATTTAAGAGTAGAGGTTTATCCAGCTTATGCTACAGGAGCTCTTATTAGTAATAGCCCTGCTGCAGTGCAAACTACAACTTTTACCAATACCAATTTGGCAAATACCTCTATCTTACATTCTTATTTTGGATTTGCAGGAAATAGAATTACTAATTTTGATGACTATTCAATGAGTTTACAAGGTTCTTCAGTTATTGATGCTGGAACACCTGTTGTTTTAGGTACAGCCGCCTTAAGTGGAAGTACTATCAACTTAAGTGGTAACGTAACTGATGAAAGAAATTCTACCGTTTCACAGAAAGGCTTTGTTTGGAGCAAGACAGTAGCAGATCCTACTACCGCGGATACTAAAATCATAGCATCTACTGGTGGTTTAGGAACTTATTCTGCTCAAATAACTGATGTTACGGCTGGAACTTATTATGTAAAAGCTTATGCAATTAACGCTATAGGAACAAGTTATGGTGCCTTGCAAACCATTACGATTTCGGTATTACCCGTTTCATTAATCAGTTTTACAGCAAAAGCTCAAAATAATAGCGTTATTTTAGACTGGAGCACATCATCAGAACAATATAACAGTCATTTTAAATTAAGTTATGCTACAGATGGCGCAAACTTTACTTTATTAAAGCATGTGTCGGCTTCCATAAATGGAAACATCAAAAACGCTTATTCTTTTGCGCATTTAAGTCCTGCAAACGGCGCTAATTACTACCTTTTAGAACAAGTAGATTTAGATGGTACAGTTAAAGACTTAGGTATTAAAGCGGTGAATTTCTCTCTATCTAAAACTACGCAGGTAGTATTTTATCCTAACCCACCCAAAATGAGGTAAAGGTGAACTTTGAGAAAGACTTTTATACCACTGCAAAACTGATTGACTTACAAGGTAAAATCCTACAAAAGAGAAACATTTCAATAGCAGACACCCAATTAACATTTGATTTAAAATCTTTGGATGCTGGGAATTATTTGATTCAGTTAGAGGGCAAGGGAACGAATGTTCAAAAGGTAGTAAAGGAGTAAATTTAACCTTAAAATATTTACAACAACCAGTACCCGAAAAGTACTGGTTTTTTTATTTAAAAATTGTAGCAACAGAAAATTCAATAGTATCAAAAATACAGGAACTAGGGGTTAAGACTATAAATTAGCCGACTTAACCCAATAATAAAATCAATTTATGCTCTACCCCGGTAAGGAAGGCGTCACAGGAGCTTAATAGAAGCACTTTTTAGCGCTATAAAGACAACTCATAAACATAAAACATGGTAATTTAACTGTGTCTACTACTCTATATGACTTATGTTTATACAACTAAAATTGAAACAAAACTTTGATGAGTTGGTACTGAATATGTTCATTTTGCTGAAATTATTTTTGTAATTTTATATATAAAAATTCAGCAAATGGATCTACAGACACGAAAACTAAATATTATCCAATACCTGATAGAACTTAAGGATGAGAAGTTGTTCAACAAGATTGAAACAATTATTAAGGATAAGATTGGTAATGAAAAATTAAAACCGTTTACTCAAGAAGAATTATTAAGTAGAATTAAACATTCTAATGATGATTATCTTACAGGAAACTTTAAAACGCAAGAACAACTAGAGATTGAATCTGAGAACTGGTAATTCGATGAAAATAATCTGGACTAATTTTGCAATTGAAAACCTTAAAGCCATCACTAAATACTACACTAAAGTAGCAGGAAAAAGTATCGCATATAAAATAAAAACAGAGATATTTAAATCTACCAAACAACTAAAGCATTATCCTGATTCCGGTCAGGAGGAAATCTCTCTTAAGTAACTAAATGAAGGATACAGGTATATTGTCAACGGAAACTATAAGGTAATTTATAAAAGAGTTGCAGAAGGAGTTCTGATTACCGATATATTTGATACTCGCCAAGACCCGGTTAAGATAAACGATCCGAAGCGTAAATAAATAGTATTAAGCTAAGCTTTAATAAACCTTTTCAGCTAATTTAAATCAGTAACTACTACCAACGGAAATAATCATCAATCTTCTACTCAATTCCAACCTCATTTAAAAAAAATCCCAAATAAATTCCCCCTCCCCAAATCATACCTCCCCCTCAAAATTCCTAGCACAAAAAAATTACAATCACTAGCGGATGATTATAAGTAGATTAGGATACTAAATCATTTGTATGAAGAAAATATTACTATTAATAGGGGCATTATTTTGCGTTGCTATGGTGCAAGCTCAGGAGACATTTCCTGTCAATGGATCATACGATATACGTAGTGGCCAGTTTGCTTTTACCAATGCCAATATTGTGGTAAGTGCAGAGCAAACCCTTAAAAACGGCACTTTAATCATTAAAGACCGTAAAATTGAACAAGTAGGTACAGCGCTAAACATCCCGAAAGGTTATGTGATTATTGATTTGAAAGGGAAATACATTTACCCTTCGCTTATTGATGCTTATACTTCTTACGGTTTGCCAGAAATCCCTCGTCAGAGTTTTAGCGGCAGAGGTTCTGCACCGGTGTTTACCACAACCAAGCAAGGTGCTTATCATTGGAACGAAGCCATAAAGCCAGAAATGAATGCCCATAGTATTTTTAATTTGGAGGCTAAAAAGGCCGAAGAAATGAAGAAAAACGGTTTTGGTACTATAAATACCTTAATTAAAGACGGTATTGCCCGTGGCACTTCTGCGGCAGTTACCCTTGGCGATGAAAGTAATAACTTAGTGATGCTATCGGCTAAAACAGCTGCAAATTATTCTTTTAGCAAGGGTACCGCAAAAACAGATTATCCGAGTTCTTTAATGGGTTCTATTGCTTTGTTACGTCAAACTTATATAGATGCGGCTTGGTATAAAAGCCAAAGTAAAGAGTTTAATATCTCTTTAGACGAGTTTAACAAGCAACAAAGTTTACCTCAAGTTTTTGAAGTAGAAAACTGGGAAGATGTTTTAAGAGCCGATAAACTAGGCGATGAATTTGGTAAGCAATACGTTTTTAAGTCGGGCGGCGATGAATACCAACGCATAGCAGACATAAAAGCTACCACAGGTAAATTTATCATTCCTATTAATTTCCCTAAAGCTTATGATGTGGAAGACCCTGCCGATGCTCGCTCTGTAACCTTTGCACAAATGAAACATTGGGAATTGGCACCTACCAACCCAGCTGTGTTAGAGCAAAACGGAATCACTTTCGCTATTAGTCCTGCCGGCTTAGAAAGCCCTAAAGATTTTTGGACCAACCTACGCCTAGCCATTGATTTTGGTTTATCAGAAAAACAAGCTTTAAAATCTTTAACAGAAATACCCGCTAGCATTTTAGGGATAGATAAAAAGGTTGGTACCTTAAACGTAGGTAAAGAGGCTAATTTCTTAATTACATCATCGCCATTATTTGCTAAAGAGAACATCATTTTTGAAAACTGGGTGCAAGGCAAAAGGTTTATAGTTTCACAAATGGATGTGAAAGATTTACGTGGCGATTATGATTTAGTGATAGCCGGCTTAGGCAAGCTAGACATGAAAATTGGCGGAAGCATTGGTGCTTATGAAGTAAATATTGTAAGAACTGGAGCTGATAGCGTAAAAACAAAAGCAAATTTTGTGCGTAATGGAGATTTGGTTAATCTGGTTTTTGATTTAACCAAGAATCCTAAAGGTGATTTTAGATTATCAGGCTATTTAGATAAAGCATCACCTTTAACTTTTAAAGGTGAAGCGGTTGCGGCTAACGGAAATACCACCAATTGGTCGGCAACTTTTAAAGCTCCTTTTATAGAAAAAGAAAAGAAAGAAGAAGCCAAAGGTGTTAGCCAAGTAGGTAAAGTTGTTTATCCATTAGTGGCTTACGGTAACCCAGATTTGCCCAAGACAGAAGCCATTATTTTTAAAAATGCTACCGTTTGGACAAACGAAAAAGATGGTATTTTAAAAGATGCTGATGTTTGGGTAGAAAACGGTAAGATTAAAGCCGTTGGTAAAAATTTAAGCACCAACAATGCTAAAATTATTGATGCTAAGGGCAAACATATAACACCAGGTATTATTGATGAACACTCGCATATTGCCATTAGCAGAGGTGTGAACGAAGGTACCCAAGCTGTTACTTCTGAGGTGCGTATTGGTGATGTGCTAGATGCTGAGGATGTTAATATTTACAGACAATTGGCCGGTGGCGTAACAACATCGCATTTATTGCATGGCTCTGCAAATCCTGTTGGTGGACAAACACAATTGATAAAATTGAGATGGGGAAATACACCAGAGGGATTGAAATTTGGTAATAACCCGGGCTTCATCAAATTTGCTTTGGGCGAGAATGTGAAGCAAAGCAATTGGGGCGAGTTTAATACCATCCGTTTTCCGCAAACCCGTATGGGGGTAGAACAAGTTTTTATAGATGCTTTTACTAGAGCTAAAGAGTATAAAGCTGCTATGGCGGCTTATAACGGCGCTAAGAATAAATCGGGTTTAACCCAACCCCGTAAAGATTTAGAGTTGGAAGCTTTAGTTGAGATTTTAGACGGCAAAAGACATATTACTTGCCATTCTTATGTGCAATCAGAAATAAATATGTTGATGAAAGTTGCAGATAGCATGGACTTTAAAGTAAATACTTTCACCCACATTTTAGAAGGCTATAAAGTAGCTGATAAAATGGCCAAAAGAGGTATTGCTGGTTCTACTTTTTCAGATTGGTGGACGTATAAAATGGAAGTGTTAGACGCTATTCCGTACAACGGAAAGCTGATGCATGAAGCCGGAGTATTAACCGCTTTCAATTCTGATGATGCTGAAATGGCTCGTCGTTTAAACCAAGAAGCTGCCAAAGCAGTTAAATATGGTGGTGTTAGCGAGGAGGAAGCTTTAAAATTTGTAACCCTAAATCCGGCTATCATGATGCATATTGATGATAGGGTGGGTAGCCTTAAGCCCGGTAAAGATGCCGATTTGGTTTTATGGTCAGAACATCCTTTATCTGTTTATGCTAAGGCAGAAAAAACGCTTGTTGATGGTATTGTTTATTGGGATTATGAGAAAGATGAGCAGAAGCGAAAAGAAATTAAAGAAGAGCAGGCTCGTTTAATCCAGAAAATGATTAATGCTAAAACTAAAGGAGCAAAAACACAACGTCCGTCTTTAGAAAAACCAAGTCTGTATGATTGTGACACTTTAGAAGGTGAGCATGCTGAAACCGAAGAACATTAATAGCTAAACATCATGAAAAAAATCATATATCAATTCATCATATTAACGGTTGCGGCATGTACAGCTTATGCGCAACCCAATATAGCTCCGGCTAAAGCCCAAACTCAGGCAATTGCTTTGGTGGGTGCTACGCTGCATATTGGCAACGGTACCGTAATAGAAAATGGGATTATTGTTTTTGATAAAGGTAAAATTACCGCTGTTGGCGATGGTAAAACAGCATTACCGCAAAATGCAAACGTTATTCAGGTTTCAGGAAAACATATTTACCCAGGTTTTATTGCCCCGGCTAATGGTTTGGGTTTAACCGAGGTAGAATCTGTAAGAGCTACCAGAGATATACAAGAAGTAGGCTTTATCAATCCGCATGTAAGGTCTATTATTGCTTATAATACCGATTCTAGAATTATCCCTACGGTACGTTCTAATGGTGTTTTACTTTCTCAGCCAGCGCCAGAAGGTGGTTTGGTTTCAGGAACATCCTCTATAGTGCAGTTAGATGCTTGGAATTGGGAAGATGCAGCTTATAAAACCGATATGGCTATCCATTTTAATTGGCCAACATCAAGAATAAGAACCAGCAGAAGAGCAGGGGCGGCAGTTAGCGAAGAACAGCAAAAAGAGCGTTACCAAAGGCAAATGGCCGAGTTACAAAACTATTTTGAAGAAGCTAAGGCTTACGCCGAGCTTAGTAAACCTAAAGTTTTTAATGCTCGTTTTGATGCAATGAAAGGCTTATTTACAGGTACTAAAAAAGCTTTTGTAAATGTATCAGCACAAAAAGATATCATTATAGCCGTTAAATTTTTCGAAGGGTTTGGTATAAAACCTGTTTTGCTTGGCGCTGATGAGGCTATACAAGTTGCAGGATTTTTAAAGGAGCATCAAATTCCTGTTATTGTTAACGAGAGTCATGCTTTACCAGCAAATGATGATGACGATGTTTACCTTCCATACAAAAATGCAGCACTTTTACATAAAGCAGGGATATTAATAGCCATGAGTATTGAAGGTTATTGGCAGCAACGTAATTTACCTTTTATGGCAGGTACAGCAGCGGCTTATGGTTTAAGTAAAGAAGAAGCTTTGGCTTTAATTACATCCAATACAGCTAAAATTTTAGGTATAGATAAACAAACAGGTACTTTAGAGATAGGTAAAGATGCCAATATCATAATTTCTGAAGGCGATGCTTTAGACATGCGAACAAACAATATCAGCAAAGCTTATATCCAAGGTCGTGATATAAATTTAGACAATGTTCAAAAGCAATTGTACAAACGCTATGCAGAAAAATTAGGTATCAAAGAGTAATTTGAGCTAAGTGTTTTAACGATATTAAAGGCAGCGTCTCCCTAGAAAGTGACGCTGTTTTTTTGTGGTATTTATCTTAATGCTATTGTTAAGTTAGAATCACTCTTTTATTAATTTTCATAAAAACCCTATTTCATTCATATAGATTTTTATATTTGGTTAATATCTGTTTAATGATTTTAAGGGGGCCTAAAATAAAACAACTATTAAGAAGTATAGCGCTTTTAGTGTTTTTACTGTTGCCTATTTTTGGCGCTGCTTTTCAAAAGGCGTATCGGCTAAATCCCCAACTTAAAGTTTATGATTCTCTGGTAAGCAGGTATAGGTATTTTAAACCAGACTCTGCCCTTTATTTCATGAACCAAGGCTTAGAACTAGCCACTAAGTTAAATGATGCTAACGGGAAGGCCGTGATGCTGAATCAATGGGGGATGATTTATGACAACAAAGGGAACTACCAAGAATCTAGAGAAAAGTACTTACAAGCCCTAAAAATTTACCAAAAAACAGGTTATGTAAAGGGTATTTCCGCTGTGAATATACGCCTAGGCGTAGTGGAAAATAGAAAAGGTAATCATGATAAAGCTATAGCTTATTTCCTAAAAGCATTGGCTATTAGCGAGAAAAATAATTATGCTTATGGCATTATGGAAGCTAACCTTACCGTAGCAGAGGGTTTTCTGGGGCAAAAGAACTACCCGATAGCTTTAAAATATTTAAAAAAAGCAGAATTTATTAGTGATACCATCCCTTTTTCAAATCTTAACCTTAACATTTACAATAATTTTGGGGTTATCTATAGAGATATTAAAAAATATGATTTAGCCGAGTATTACCTTAAAAAAGGCATCGCTTTAAGCAGTAATATTAAATACCAAGGCCTAAATATTACGCTAACCAATAATTTAGCTAGTGTTTATGCTCGTACAGGAAAAAAACAGCAAGCTATAGCGCTTCAAAAAGAAGCGCTTAAAAAGGCTAAAGAAATACAAAATTTCTTAAGAGAAATAGAGGTTTTATTAGGTTTAGCAGAGAATTATAAAGATACCGATAGTAAAAAGGCTCTGGCTTATTACAAAGATGCCTTAAACCTCACCAGAAAAAATAATGCCTATAAAAGACAGGTAGAAATTCTAAACCAAATGGTAATTCTTTACCGCAAAGAGGGCAATTACAAAGAAGCTTTAACCTTAAAAGAAGAAGAAAAAAACTTAGCAGATAGCTTTTTGTATAAAGATATCGATAGTCGCATTAGCGATTTACAAGCCCAGTATGAGCTGGCTAAATCTCAAGCCCGGGTGAAAGAACTGCAATACAGCAATACCCAACAAAATTTGCGTAGCACCATTATCTTAAGTGTTGCAGTATTTGTTATGATTATTCTTGTTTTTATGGTTTTTAACAACCGCAGAAACAGGAAATTTAATCAGCTTTTGTCTAAAGCCAATCAAGAATTAAAAGAATCTAACTCGGTAAAAGATAAATTATTCTCTGTTCTGGCCCATGATTTAAGAGGACCATTTGCAGCTATTATCAACCTTTTAAGCATGGTTAAAGATGGTTATTTAGACGAGCGAGAGAAAAATGAGTTGATTGATAAAATTACCCAAAATAGCACCACTTATTTAGACACCCTAAACGATTTAGTGAAATGGGGCGAAACACAAATTAAAGGTTTAAGAATAAATCCGCAACCCATAGCCCTAGCTCAGGAAGTTGAACTTAATAAGGAGTTTTTAAGCGTACTTATTGAGGATAAGAATATCAGTTTCAGTAATGAAATACTACCTCATGTAGCTGTTTTGGCAGATAAAGCCCACTTTGATTTAATCATCAGAAATTTATTAAGTAATGCCGTAAAATTTACCAATACGGGAGGCAGCATCAAGGTTTTTGCAGAAGATGAAAGCCAATATATCAGAATTACAGTTAAAGATACAGGCATTGGCATGTCTGCAGATAAGCAAAGTCGAATTTTTAATTTTGAAAACATCAGCTTAGCAGGCACAGGTAATGAAAAAGGAAATAGCTTAGGCCTCATCTTGTGTAAAGAGTACGTTTTAGCAAATAAAGGCACCATAAGTGTAAAGAGTAAAAAAGGCGAAGGTTCTGAGTTTAGTTTTACCTTACCTAAGGCTTAAATCACGTAATTTTAATAGAGAACATCATGCAATTTGGAAAAGTAGAAGATCCATCAATCATAAATTTCAGCCTTCCGGCTGATGCTCCTGAAACTAAAGACTTACTAAAAAACACTTCAAAAAGTACTTTTGAAGCCTATGTAGGATGCGCAAAATGGAATAAAGCCGATTTAAAAGGATTTTATCCAAGAGGTACAAAAGACGAGCTAACTTACTACGCCACGCAGTTTAATAGTATTGAGCTAAATGCTACTTTTTACAATTTGCCAAGTAGCGCACAAGTAAGCAGTTGGAGAGATAAAACACCCGATGATTTTAAGTTTTTCCCTAAAATAACCAACTCGGTGAGTCATTACCGCAGGTTAATAGATGTTAAAGAACCTGTTACTTTATTTTGCGATGCCATTAGCCATTTTGAAGAAAAATTAGGGATGGCTTTTTTGCAACTGCATGATAATTTTAAGCCTAAAGATTTTGACCGACTTAAAACTTTTGTTGAAGATTTTCCAAAGGTAATTCCACTGGCTATAGAGGTTAGAAATGAGGAATGGTTTACCAATAAGGCTATTGCCGATGAACTTTACCAATTGTTAAAAAAGCATCATATCACCAATGTTTTGGTAGATACAGCAGGCAGAAGAGACATGATGCACATGAAATTAAGCACACCTATTGCTTTTATTCGTTATGTAGGTGCTAATCATGAATCTGATTATAGCAGATTAGACGAATGGGTAAAACGCATTGTTGATTGGAAAGCGGCTGGTTTACAGAAACTGTATTTCTTTGTTCACCAAAATGTAGAGCTGGCATCGCCTTTATTGTCTGCTTATTTTATAGAAAAATTAAATAAAGCTATAGGTATAAAGCTTCATATTCCTGTAATGGCAACGGAAAATCCTACTTTATTTTAAACGTTTAACAGATGGAAAATTTCGAATCTGTTGAGGCATATATAGCCCATTTCCCTGAAGAAGTGCAAAATCTACTTAAGCAAATAAGGGTCATCATTAAAAGGATTGCGCCTGATTCGGTAGAAGGCATCAGCTATGGTATGCCAGCTTATAAGCTTCATAAAAAGCCATTGGTTTACTTTGCGGCTTTTAAAAAACATATCGGTTTTTATGCAACACCTAGTGGGCATACTGCTTTTTCTGTAGAGTTGGCTGCTTACAAACAAGGAAAAGGCTCAGTACAGTTTCCTTTAAACAAGCCTATTCCTTATGCTTTAATAGAAAAGATGGTAGCTTTTAGGGTAGAAGAAAATAGGGCAATCCGTTACCGTTAATCCACCTTGTTTTTTAGTTCTTCGCCATTGCAAAATGCATCAATATTAGCAAAAGAAACTCTTGCTATTTCGCCTATAGCTTCTTGCGTAAAAAATCCTTGATGTGAGGTGATTAAAACATTAGGAAAAGAAATTAAGCGGGTAATCAATTCATCTTGTATAATTCCTTCTGATAAATCATGGAAAAATAAATCTCCTTCTTGTTCATAAACATCTAAACCTAAAGCCCCTAATTGGCCGCTTTTTAAGGCTTTTATAGCATCTTTGGTATGTACCAAAGCGCCTCTACTGGTATTAATCAGCATGGCGCCATGCTTAAATAGTTTTAATGTTTTTTGGTTGATTAAGTATTGCGTTTCTGGCGTTAAAGGGCAATGTAGAGATACAATATCAGCATCGCATAAGGTTTCTTCTAAAGTGCCGTATTGTACGCCCATGGCTTTAACTTCGTCTTGCGGGTACAAATCATAAGCACTTATTTTACAGCCAAAACCACTTAATATTTTACAAAAAGCTTTACCAATATTACCTGTGCCAATAACTGCTACTTTACGGTTGTGTAGGTTAAAACCCATTAATCTTTCTAAAGAAAAATTACCCTCGCGTATGCGGTTATAAGCTTTATGTGTTTTGCGGTTTAAAGTTAAAATCAATGCCATAGCATGCTCTGCAACGGCTTCTGGTGAATATGCAGGCACTCTTACTACGGTTATGCCCATGGCTTTTGCATCGGCTACAGCCACATTATTAAAGCCAGCACATCTTAAAACAATTAATTTAATGCCTGCAGCTTTTAATATTTCTAATACCGCTTTATCTACTTTATCATTTACAAAAATACAAATGGCATCAAAACCATTAGCCAAAGGGGCGGTATCTGCATGAAGCGCTAGGGTGAAAAAAGTAAGCTCATGACCGGTATTGTATCTGTTTAAAAATTCTTCATCGTAATGGTAGGTGCTAAAAACGGCAATTTTCATATTGTTAAGCGTATTTTTATGAGTGTAAGCTAAATCTTATTTTTTTAAATGATGATGCAAGATACATATTTGTATACTGTAGGATAAATGATCTTGATTACAAAATGGAGGCTTTTCATTAGTAAGTTAGTTTTGTTGGATAAAAGATTTGTAAGCTAAGTGATGAATGGGCCCTGCCGGCTCTTGAGGCGGATATTTATTGTTTTATGGGGATTGTTAACTAATTGGCTATTGCGCACAAGGCTTTCCGGCCTCATAGGCGGCCTGCCCTATTTACTTTTTTCTTGATAAAAAAGTAAACAAAAATTCCTACCTACCGGCAGGCAGGCAAGGCTGATGAATATTTGTCGTTTCGCCTAAATAAATCTTCATCCACAATCCTGAGTGGTGTGAATGGTTTTGCTAAATGATAGCTTCTACAACACCCGTCGGATTGTTTCCCGATACTGCTTCATGAAAGTTTTTGCAAAAGATTTATTTGCCTACACTTCCAAATATTCATAGGCCATCTTTCGTTCTTCGGAAAAGTATTGTTTGGTTTTTAGAGGTAGCACCTAAATATTTGCTCTTTGGAGTCTTTATACTCTGTACTTTCTACCGATAGAAAGGAACAACCATTCATAAGAAAACAGCCTAAACCGAAGTGCATGAGCAATCCCCCAGAGCTGGGAAGACGAAAAAACAGCAGCAGAAATTAAAAAATCTTGCACAACCAAGCCTATAGCGAATGCGGTTTTGCGTTCGAGTTTATACTAACATTGAAAAACCACATCCGAGCAAAAATAAGCACTCACTGTTTTTGAGTGTGGGAGAGCTTTGTGCGGCAAAGGCTCCAGCGGGGATTGTTCAGGACTTTATTCATTATTTTTTATTGATTTTTAAAGGTATTCATGAATTCGCTAAAGCTTCATTTTGGTTCCTTTTGGTCCCTCAAAAGGAACGAGCCCCGCCGGCGATAGAGGCGGATGAATATTATTTTTAAAAATAGCTTGACTAATTGACCGTATCACACAAGTCTTTCCTGCCTCATAGGCGGCCAACCCTATTTACTTTTTTCTTGATAAAAAAGTAAACAAAAAACGAGGAACGAGTTCATGAATGCCTAAGAAAAACCATAAATAAAAAATGAATAAATCCTGCCTACCGGCAGGCAGGCAAGGCTGATGAATATTTGTCGTTTCGCCTAAATAAATCTTTATCCACAATCCTGAGTGGTGTGAATGGTTTTGCTTTGCGTAGGCATCTACAACACCCGTCGGATTGTTTCCCGATACTGCTTCATGAAAGTTTATACAAAAGATTTATTTACCTACACTTCCAAATCTTCATAGGCCATCTTCGTTCTTCGGAAAAATTTGATTTAATATTATTGGAAGTCCCTAAATATCGCTTTTTAGAGTCTTCATACTTTAGACTCTGTACTTTCTACTATTCAATATCCGCTCTTTAAGATCTTTTTACTTTCTACGCTGTACTTTCTACTTTAAAACCTTTCCCCATGCGTCTTACTTATCAAAAAAGAAAAAACTTTAGGAAAATGGTTAAGACCACCAATAGCCATTTCTGATAATACATTCTGACCAAATAGTTTTTGTATGGTTCTGCCTATAAATAATCTTTGTGCAAATTCTTGCTGCCATGTTTGGCTGTAAGCTTTTTCTAGTTGGGCTCTTTTAGTTGGGTTAATGCCATCAGGGCAAATATCAATAATGCAAGAGCTTAAAATTTTTGCCGAGTGTATGGCTATAGCCATGCCGTTTCCGCAAAGTGGAGCAATCATACCGGCAGTATCGCCACACATCAAGATATGGTTTTCTATCAATGTTTTGCGCTCAAAAGCAATTTCATTAATGGTTTCTGGCTTATCCCAAATAAACTCGGCATGGCGAAATACTTCTTTTAAAAAAGGGTTTTTGCTTAACACTTGCTCTTCTACAGCGGCTATAGAACCATATTTTTTTAAATGCTTATTTTCTGATAGGTAACACAAGCAATAGCTATCTGTACCGATGCTGTTTAGGCCACAATAACCACCTTCAAAATTATCTAAGCGGATGGTATCTTTAGGGAAATCTAACTTTACGTGATATTTAACACCCATATAAGGGCTGCGCTTATAAAAGGAGGAACGTTGGAGTTGCTTATCTAAGTTAGAGCGTTTGCCAAAAGCACCAATCACCAAATCTGCCTGATAGGTTTTACCAGCTAGCAAGATATTAAACTGTTCATCATGATATTGGATATCCGTAATTTTTTCGCCCAAAAGAAATTCCACACCTTGTTGTTTAGCGATGAGGTAAAGCTGCTCATCTAGCGTATATCGGCTGATGCCAAATCCGCCCAAGTCTAAAGGGGCAAGAATGGTTTTTCCTGAGGGCGCAGCAATAATTAACTTTTCTAGTTTACTCGCCTGCAAATCCTCGGGGTTTAACCCCAAACTTTTTAAAAAAGGTAAAGCTTCATTGCTTACATACTCGCCACATACCCTATGGAAAGGGTAAAATTTACGCTCGGCAAGGCAAACTTCAAAACCTGCTTTGCTTAATAAAATGGCGTTGGTAAGGCCTGCTAAACCCCCTCCGGCAATAAATATTTTTGGTTTTTTGCTCATTTATAAATGATGATTTGCCAGCGAAAGGCCCACATCCATTTAATACTATACTTCTTAATACCCATTTGCGCTAATAATGTTTGCAACTCTTTTCTGGTAAAACTTCTCAAGACTGATAGTTTGCTATCGTGTTTTACCATGGGCGATTTAGAAAATAGCTGGGTAAGCCAGCCAATGGAATAATAAGCAAACCAATGGCGGTGCAAATCATTAATAATCACAGCTTTTTTAGAGGTATACAACATTCTTGCTACCAGCTGTTTCCATTCATCATTGTTAAAATGATGGGTAAACAAGCTGCTGATGACATAATCAAACTCTTCGCTTAAAAAAGGCTCTTCCAAAACATCTGCCAACCTAAAGTGAATATCTGCTGTTTCATGATGTGCCTTGGCAAAACTAATGGCACTGGGGGTGGCATCAATCCCGATAAAGTGGGGGTATATTTTTCTTTTATGGAAGTACTTTTTTAAAACTTTTAGGCTATCGCCACCGCCACAACCCCAATCGCAAATGATATCTTTATTACGGATTGGTAATTTCTTAAAAGCATTGTAAAATACCTGAAAACCGCCTAGCAATTGGTTAATAACTTCCAACTCTTTCAATACAGGATGGATGGCTTGTTGGTCTAACGAGAAATCATCCATGATTTCTAACGCTGTACTTCTATGGTTAAAACTAGGCATATGTAAGTACCATGCTTTCAAAAGTTAAACCAGGACCAAAAGCAAAGCTCAATATTTTTTCTTCCTGTTGTTTGGTTTTGAGCTTTTTACTGAGTGCTGCTAATACAAAAAGTACCGTTGCAGACGACATGTTACCAAAATTACGTAATACCTCATAAGCATGCTCATTTTGGTGGGAATGGAGTTGAAAAGCATCATCGCAAACTTCTAAAATTCTTCTGCCACCGGGGTGGATGGCATATTGCCCAATATCATCAAAAGCTAATTGGGCTTTTTTCAATAATTTTTGGGCAATGTCTTTAATGCCACTTCTTATTTGTTTAGCAACTTGGCTGGTAAGCTGCATTTCGTAGCCAAAATCGCCAATTCGCCAGGCCATTTCATTTCTTGCCTTGCTAATCAGCTCGCTGTAAAAAGAATTGATATGGAAAAGTTTATCATCAGTTTGTGCTTCATGTTGTACCAAAACAGCCGCTGCTCCATCGGCAAATAAAGAATTTGCCAACCAGTTATCTAAAGTATTTTCCTTTTGGAAATGGAGGGTGCAAAGCTCTACATCAACAATTAAAACTTTAGCTGTAGGCTGCGCTCTGCAAATATAATCGGCCACTTTAAGCGCATTAAAAGCACCATAACAACCCATAAAATTTATACAAGTACGTTCGGTATCGGGCTTTAAGCCTAGTTTTTCTACCAATTCTATATCTAAACCTGGGGCATACATTCCTGTACAACTTACCGTAATTAAATGTGTGATATTTTGAGGATTAAAGTCGAGCTGTTTCAAACAATTTTCAACCGCTTTTAAAGCAATTTGTAAAGCATTTTGCTCGTATATAAAACCTCTGCTGGCGGTTGTAGGGAAAGGGTTAAGGCCATCATCATTACCAAAAAAGCTATAATTGCCTTTTTGCTTACCAAAATCTTGCAGTACCGAGTGCCTGTAATCTATTCCAGATACTTGATATAATTTTTCTAATCTACGAGCTTGATTGCTATCCAACTGATGCGCTTCTTTCATAAATTCCAGTATGCGACTTTGCGCAAACTGATTTGATGGATTACTGGTACCAATTGCCGATATAACACTGCTCATTCAAAAAAATTAAATATTTTTACCTTCATGCTAAACATAACAAAGAAATGAAGTCTACCTTATTACACCTACGCCTTCCCTTTTCTTTGTTGTTGCTTCCTGTTTATTTGTTTGCTTATAGCGAAGTACCTAATCCTAACATTTACAATGCCATAGTAGTTTTTATAGTTTGGCATTTATTTGTGTATCCGGCAAGTAACGCTTACAATAGCTATTTTGATAAGGATGAAGGCAGTATTGCGCTTATAAAAGAACCGCCAAAAGTGCAAAAATCTTTATTGGTAACGGCTTATGTATTAGAGTGGACAGGTTTATTGATGGCTTTTTTAGTGAGTTTTGAGTTTGCTTTGGCAGTTGCCATTTATAATTCTTTTTCTAAAGCTTACAGTCATCCTCGTATCCGCATCAAAAAATATCCTATTTTAAGTTTTTTGGTGGTTTTTATTTTTCAAGGATTTTTTATTTACTACAGTTGCTACCAAGCCATAGGCCAATATGATTTGGGGCTTAATGCCGATGTCATCCAAGCCGGATTGATTTCTTCCTGCTTAATTGGGGCTTCTTATCCGCTAACGCAAGTGTACCAACACGAAGAAGATAACAGGCGTGGTGATAAAACTTTAAGTCTTTTACTAGGTGTAAAAGGCTCTTTTTTATTTTCAGGCTTTGTATTTTTTTTGGGTTTTGCCCTGATGTTTGATTATTGGAACAGGCAAAATGAACTCCATAATTTTTGGGTTTTTGCCCTTTGCTGCTCCCCAATATTAGGCTATTTTTTATGGTGGTTTAAACAGTGTTTAAACCGAGTTGAAGCTGCATCTTTTAAAAACGCAATGGGTATGACGCTTATTAGCGGTTTAATGATGTTGCTGTATTTTGGCTGGCTATGGCTCTAAAAACCTAGTCTTCTGCCTTAAAATTAGCTTTGTGTTTGATGTAGGAAATATAATTTTCTGGCAATTGGTGTTGTGTAGCACCTTCTAATAAGGTATTTAGATATTCTTCTTCTGGTGATAGCTCTTCTGCTTCATCTACACAAATAAAAGCATAAGCTTGATGTATGCCTGTATCGCTTTCAAGCTCAAATTCTTGTAATTGGTATTGAGGTTCTGTTTGTTGTAATAATTCAAAATGTTTGGCATGTACTTGATACAAAACACCATGTACATTTTCACTTTCAGAAACTACCAAATTGGCTCTGGCACTACCATCGGCGTTAAGCTGATGAAAGCATAAACCATAACCATATAAAACGGCTGACCCAACAACTGTTACAGGGTCATTAACCCTAAATTCCATTAATGCTTTATTAAGATTACTACCGTAAGCGAAATATAAAAAAGTGTTTTCCATGGTTTATTTTTCTCCGTTCCATTCTGCATAGAACTGAGTCAAATATTGAACCATAAAATCATGTCTTTGGGCTGCCAATTTTTTGCCTGTTGCGGTGTTCATCTTATCTTTCAATAAGAGTAGTTTTTCATAAAAATGGTTGATGGTTGGAGCGGTAGATTTTTTATAAGCCTCTTTACTTTGGTTAGGCTCGGGTTTAATCTCAGGGTTGTAAAGTTCTCTGTTTTTATAACCGCCGTAAGTAAAAGCTCTGGCAATTCCAATAGCACCAATGGCATCTAGCCTATCAGCATCTTGTACCACCAACATTTCTGCTGAAGTAAAAGTAACATCGCCTAAGCTAGCTTTAAAAGACATGTTTTTGATAATTTGCTGTACGTGGATAATAGTTTCATCATCAACAGCTAAAGTTTTTAAAAAATCGCCCGCTTTTCTTGGTCCTATTTCTTCATCGCCATCATGAAATTTAGCATCAGCAATATCATGTAGCAAAGCGGCAAACTCTACCACCAGTAAATTCACTTTTTCCTCTGCTGCGATGTATTTAGCAGTTTTCCAAACACGTTCTATATGAAACCAATCATGCCCGGCCTCGGCATTTTGTAGTTCTTGCTTTACAAAAGCAATGGTTTTGTAAATGAGTTCTTGCATTATTTTAATTTCTCGTTGTTACGATGTCTGTCTGCATCTCTAATACTTTTCTTCTCCAAATTTTTCTCTAGTGCAGCAGTTAAATCAATACCAGTTTGGTTGGCTAGGCAAATCAAAACAAAAAGTACATCGGCCATTTCATCGCCTAAATCAACTTTTTTATCAGATTCTTTAAAAGACTGCTCGCCATATTTACGAGACATGATACGGGCAACCTCACCCACTTCTTCCATTAAAATAGCCGTATTGGTAAGCTCATTAAAATACCTTACACCAGTAGTTTTAATCCAATTGTCTACCAGTTGTTGTGCTTCTTTAATTTCCATGATGCTAAAATCAGGAATCTTTAGCAATAAATAAGGGCTATGCTGTTATTTCATATAAAAAATAGGGGCAATCATAACCATCGCGTAAAAGCAGAGGTTTGGCAACATTAAAAACCTCTATACCGTCTTGTGTTTTGCCTTTTAAAGTACCAATGTGGGCATGGCCATGAAAAGCAACATCAACATTTCTTCTGCTGAGGGGTTCTGCCAATCTGGATGAACCTAAAAACGGAAAAATAGCTTCAGCTTCGCCTTTTACGGTTTCAACGATGGGCGAATAATGTAACAAAGCCACTTTTTTAATATCTTGATGGTCTGATTCTAATCTTGCTAAGGCTCTTTCTAATTGTAAGGCTTCATTTACGGCTTCTTGTACAAAATCTTTCATGCCTTTTTCGCCAAACATAGATAGCATGTGCTTATCAAAACCGCCACCAAAGCCTTTGATGCCTGCAAAGCCAATGTTATGGATAACGATAGCTTCTCCATCTAAAACATGAACATGGTCTTTTAACAAAAGCTGACGAATCATTTTCTCTCTGCCTTTCTCGTAATCGTGATTGCCTAAAACCATCACTACGGGGATGCTGCATGCTTTTAATTCTTCGGCTAAAACGGCTGCTTCAGACTCGTCGCCAGTATCGGTTAAATCGCCACAGATAACCAAAACATCCGCTTTTTCTGATATTTCTTTAAAATAGGCAGTCCATTTTCCTTTGTCAGATTCTTTTACATGGATATCGGCAACGGCAGCTATTCTAGTATTTTTTGTTGTATCTGTCATGGTATGAGAAATTTAGGTAGTCATGATGGTAGATACTTTATAGTTCCAATCTTTAATATCTACGCTGTATTGGGTTTGGTCTATAACGGGGCCTCTACAAACTTTCACTACCGTAGCGGGCAATTGGTATTGGTTATTGGCTCTTTTTATCAATTCATCAAACAACCATTGGGGGATGATTTCATGAAAATCAGACGGGTAAACAAACTGAAACATAATGATTTGAGCCAATAATAAATGCCAGTGGTTATGTTGGTCTAATCGGGAAAGTAACCTTTCCCAGTCTAATTCTTTACCTTTTTTAAGAATAACATGGTTGATATCTGCCCCATCAAAACGTTCACGATTTTGGACATATATTTTACACCAAATAAGTTCCTCGGGAGATAAAAACTTCACTTCTTCACCAGCAAAAGTACCAGGGGTAGCGTGTTCAAACCAGCTATCATCAACCGTACAAATGTTATTTACAGTATCAAAAATAATATCGATGAAATAATCTCCTTTAAAAACTTTGGCCAACCAGCGGATGTCTGTTAATTGGGTTTTATAACCTTTATCGGCAAAAAATTGTAGTATTTTGCTATAGTCTGATGGTTTACAAAAGATATCTAAATCTTTAGTATCGCGGTAAATATCAGTATGTGCAAAGAGGGAAAAGGCACCTCCTAGCATAAAATCTACACCGCACTCTTTTAGTAATTGTAAGGCTTCTTTATAGAATTCTTGAGCTTCTTTTTTCTCTTCTTCGGTTGTAATCATAGGGTTTTTAATAAGGTAGAAAACTGCTACTAGGCAGTTATTCATTATCCTTATTCAAAAACCAAACCTAAAATTAATGCCTGTCTTTATCCTTGGTATCCATCATGATGGTAACGGGGCCATCATTTAAGAGTTCTATTTTCATATCGGCACCAAAAATGCCGGTTTCTATTTTGGTATTGCTTAATTGAGCTAGCTCTGCAATCATTTTTTCATAAAGCGGAATAGCCTGGGCAGGTTTGGCAGCTCTGATAAATGAGGGGCGATTTCCCTTTTTTGTTTGTGCGAAGAGTGTAAACTGAGATATCAATAAAATACGGCCATCAACATCAGCTAAAGATTTATTCATTAAGCCATTTTCATCATTAAAAATGCGCATGTTCACAATTTTTTGCGCCAGCCAAGTTAAATCTTCTAAAGTATCAGCCTCCTCAACACCCAATAAAACCAAAAATCCGGTGTTTATTTTACCTGTAATTTCTCCGTTTACGGTGCATGATGCTTGACTTACTCTTTGGATAACGGCTCTCATATTTTAGGTTAGGTGCTTAGTAATTAGTTGGTTAGTTTGTTAGGTTTCTAGTTTGTTAGACTTTTTAAACGGCTGATTATTAATGGAAGTCCTTCTCCTTCGGAGAAGGATTTAGGATGAGGCTCTATGCCCTCGTATCGTTTTTATGATAAATACTTAAATAGCTATCATATCTTGTGGGTTCAATATTTCCTTCGTCTAAGGCTTTTAAAATGGCGCAACCGGGTTCGTTAATGTGTACGCAGTTATGAAATTTGCAGCCATGCATACGGCTTCGCATCTCTGGAAAGAAATGAGCAAGTTCCTCTGGTTCTATATCGGCAATGCCTAATTCTCTAATGCCTGGGGTATCAATTAATTTTCCGCCGAAAGGCAATTCAAACATTTCTGCAAAGGTGGTGGTGTGTTTTCCCATATCGCTCCAATCAGAAATTTCGCCAGTTCTTAAAGCAATACCCGGTATGATCTGATTGATTAAGCTTGATTTTCCAACGCCAGAATGTCCAGAAAATAAACTAGTCTTATCTTTCAGCAATTCTTTAATGGTATTCACATGGGTGCCTTCTATGGCAGATACCGCATAACATTTATAGCCTATACCTTCATACAAATCCATATAATTGGCTAGGATTTCTAGGCCTTCATCGCTAAATAAATCTAGCTTATTAAAGATTAAAATAGCAGGAATTCCATAAGCTTCAGCAGTAACCAAAAAACGGTCTATAAAGCCTAAAGAAGTTCTTGGAGAAGCCAAAGTTACCACCAAACAAGCCTGGTCTAAATTAGCAGCAATAACTTGTACTTGTTTAGATAGGTTGATAGATTTTCTGATGATATAGTTCTTACGGTCATGAATTCTATTGATGACAGCAGTTTCTTGCTCGGGTTCTAGCTCAAAATCAACAAAATCTCCAACAGCAACAGGATTGGTGCTTACCAGACCTTTCATCCTGAGTTTGCCTTTTATCCTGCATTCATATTTGTGCTGATTTTCACCTAAAACAGTGTACCAGCTTCCTGTTGATTTAATAACTAATCCCTGCATACCGTTGTAAAGATAATTATAGGCTAAATGAATTTCCTATTTTCTGTGAAAAATGTTTGTATTTAAAAAATGAAAGCTTAGATTTGGCACATAATTTAAAAACGTGAATAATAACTATGCAACTACAATTACTTACACCATGACGCTCTGCGCATAGAGGAAGGTAATTATAGGCTTATATAAAACATACAAAGCGCCTTCCGACAAAACGGAAGGCGCTTTTTTTTAAATTTTAATATCAAATCCAAAGCTGCGTGTCAGTAAAAGATTTTTAGCTGTAGAAAGAAAATGAAAATTTTAAAATTCGGAGGAACTTCTGTTGGGTCTGTAGATGCTTTAAAAGCGTTAATAGACGTGGTTAAAACTAACCTTGATAAGCAAGAACAAATGGTCATTGTTGTTTCTGCTATGGGAGGTGTTACCAACCAATTAATCACGACGGCAGAGAACGCTATAAAAGGAATTGATTTTTCTGAAGCTTTGGCTGATATAGAAAAAAGACACTTTGAAGTGGTAAAAGCGTTAATTCCTGTGCAACAACAAAATCAGGTTTTAACCAAATTAAAATTATTTTTTCAAGAGCTGGAAGATTTAATGCAAGGTGTTACGGCCTTACAAGAGCTAAGTCCAAAAACTCGTGATGCTATTTTAAGCTATGGCGAGCAATGCTCGGCTTTTATGATTTCTAGAATCTTAAAAACCATACATGAAGGTGCTGATTACCTAAACACCACAGAAATTATTAAAACTGATAGTACTTTTGGTAATGCCCGTGTAGATTTTGAACAAAGTAATTTCTTGATCAAGAACTACTTTGAACATCATAAAGATAGTTTAATTGTGGCTACAGGTTTTATAGCTAGCGATGACCAAAACAGGGTAACAACTCTTGGTCGTGGTGGTAGTGATTATACTTCTGCCATCATTGGTGCGGCTTTAAATGTATCGCAAATAGAAATCTGGACAGATGTTAATGGCATGATGACTGCCGATCCAAGAAGGGTAAAAAAAGCATTTTCTTTAGAAGAACTTTCTTATACCGAGGCTATGGAGCTTTCTTTCTTTGGGGCAAAGGTGATTTATCCGCCAACCATGATTCCGGCTTTCTTAAAGAAAATTCCAATTGTTATTAAAAATACTTTTGATGCTAGTTTCCCAGGAACTTTTATCAAACATGATATCAAGCCATCATCAACCGTTATCAGAGGGATTTCTTCTGTAGACCATATCAGCATTATCAATTTGCAAGGTAGTGGCATGGTTGGTAAAGCGGGTTTTAGCGGCAGGTTATTCTCTTTACTGTCTAGAGAGCAGGTAAACGTAGTTTTAATTACACAATCATCATCAGAGCACTCTATCACTTTTGCGGTTAACCCTGAGGATGCTAAAAAAGCACAAGCTTTAATTCAGCAAGAGTTTGAGTTAGAATTACAAGCCGGAAAATTAGAGCCTATCACCATAGAACATGATCTTTCTATTTTAGCCATCGTAGGCGAAAATATGAAGAAAACACCGGGTATTGCCGGAAAACTTTTCCATGCTTTAGGTAGAAATGGTGTTAATGTGGTTGCTATAGCGCAAGGTTCATCAGAATACAATATCTCGGTAATTATTTATAATTCCGATTTGACAAAAGCTTTAAATACCGTACACGATGCGTTTTTTGCACAATTGCAAAAGAACTTAAACGTATTTATTGTTGGTGTGGGTAATATCAGTAAAGAATTGCTTTCGCAGATAAATGCTCATCATGCTTATTTAGTAGAAAATAATCTCATCAATATCAAAATCATCGGTTTAACCAACACTAAAAAAATGTTGATAGAGCCAGCTGGTATAGATTTAGCTAATTGGCAACAAAGCTTAGATGAATCAACCGAGCCTGCAGATTTAAATAAATTTGTGAGTGAGATGAAGAGCTTAAACCTACCAAACTGCGTATTTGTAGATAATACTGCAAGCCCAATTCCAAGTACTTTATATAAAGATATTTTCAAGTCGAATATTTCCGTGGTTACTTGCAATAAAATTGCTAACTCTGGCGATTATAAGCAGTTTGCAGATTTAAGAAGTACTGCTCAGAAATACGGAGTAGATTTCTTGTACGAAACCAACGTAGGTGCTGGTTTACCTATCATCACCACATTACATGATTTAATCATCAGTGGCGATAAAATCACCAAGATAGAAGCTATTCTTTCTGGTACCATCTCTTTCATTTTTAATAATTTTAAAGGTGATGTTACTTTCCACGATGTAGTTAAGCAAGCACAAGAAAAAGGTTATACAGAGCCAGATCCTCGTGATGATTTAGGTGGGATTGATTTTATGCGTAAAATATTAATCTTAGCCAGAAATAGTGGTTTAGCAATGGAAGCTGCTGATGTAGATTTAGGAGCTATTTTACCAGAAAATTGCGCTAAAGCACCAACTGTTGAAGCTTTTTATCAAGAGCTAAAAGTTTCTAACGATTATTTTGAACAGCTTAAAAAAGATGCTGAAAAACAAGGTAAAGTACTTCGTTACATTGGAAAATTAGAAAACGGTAAAGCAAGCATTAGCCTGCAAGCAGTAGGTATGGATCATCCTTTCTACGCTTTATCTGGTAGCGATAACATTATAGCTTTCACCACCGAGAGGTATTGTGAAACACAAATGGTAGTAAAAGGGCCTGGTGCTGGTGCTGCGGTTACCGCTGCTGGTGTATTTGCCGATTTAGTTAAAGTAGGAGCTAACCAGTAATGAGCAGTAAATCAATAAAAGTATATGCCCCAGCTACTGTTGCTAATGTGGTGTGTGGTTTTGATATTTTGGGCTTCGCTGTTAATGAACCGGGCGATGAACTCATCATGGATCTATGCGATAAACCTGGCGTAGTCATAAGCTCTATAGAAGGCGATGGTGGTAAATTACCTCTCGATGCCGACCGTAACACAGTAGCTGCAGGTGTTAAAAGCATATTAAAACAACTTGGTCGTGAAGACATCGGCGTTAAGCTAAAACTAAAGAAAAAAATGCCTTTAGGTAGTGGCTTAGGTTCTAGTGCAGCTAGTTCTGTAGCGGGTATATTTGCTATTAACGAATTATTAGACAGGCCTTTAAGCAAAGAAGAATTACTGCCTTTTGCTATGGAAGGCGAGGCTTTAGCTTGTGGCCATGGTCATGCCGATAATGTTGCACCTGCTTTATTTGGCGGTTTTACCCTCATTAAAAGTTATGAGCCTTTAGAGGTGATAGCTTTACCAGTGCCAAATTTATATTGCGCTTTATTGTATCCGCATGTTGATGTACCTACTAGAGATGCCAGACAAATTATACGTTCTAAAGTATTGTTAAAAGATGCAGTTACCCAATGGGGAAATATTGCTGGCCTAATAAGTGCTTTATATCTGGGAGATTACGATTTACTTGGACGTTGTATGAAAGATGTTATTGTAGAGCCCATACGCTCTATGTTGATACCAGAGTTTTATAAAATGAAGGAAATAGCCATGCACCACGGTGCTTTAGGTTTTGGTATCTCGGGTTCGGGACCAACTGTTTTTTCTTTATTCCGTTCGCCGGATGACGCACAAAGGGTATTATTAACCTTACAACAAGTGCTTTTAGACAAAGGTATCGCCAGTAACATATATTTATCAGAAATTAATAAAAACGGACCAGTTATACTATAGTAGTTTGTTAGGTATTAGTTTGTTAGGAATCAACTAATCATCCAATCAACTAACCATCCAACCATCTAAAGAAATGAAACTATACAGTACCAAAAACCATCATTTATCGGTTGATTTTAAGACAGCAGTTTTCAATAGCCTTCCGGCAGATAATGGTTTATATATGCCTACCACTATCCCAGTTTTAGATGAAAATATCATTGCTGGTTGGGATAAGAAATCTTTACCAGAAATTGCTTTCGATTTAGCCTATGCTTTATTAAAAGATGATATTTCTGCCGAAGCTTTAAAAGCTATTGTAGATGATGCTGCAAATTTTGAGGCTCCTTTACATCCTTTAGCTGATGATGTTTTTATTCTAGAGTTATTCCATGGTCCGTCTTTAGCCTTTAAAGATTTTGGAGGGCGTTTCATGAGCCGTATCATGGCGCATTTCTTAAAGGAAGAGGAAAAAGAAATCAGGATTTTAGTAGCTACCTCTGGCGATACAGGAGGTGCAGTAGCCTTAGGTTTTTTAAATGTACCGGGTATAAAAGTTACCATTCTTTACCCAAAAGGTAAGGTAAGTTTAATACAAGAATTGCAATTAACTACCAATGGTAATAATATAGAAGCCGTAGAAATTGATGGTACTTTTGATGATTGCCAAGCTATGGTAAAGCAAGCTTTTCATGATGAAGAGTTAAATGCTAAGTTTAATCTTACCTCTGCAAATTCTATCAATATCAGCAGGTTAATACCTCAAATGTTTTACTATGCCAATACTTATGCCCGCTTAAAGCAACAGTTTGAGCATATTACTTTTGTTACGCCAAGTGGTAACTTCGGTAATATAGCGGCTGGTATGTTAGCTTCTAAAATGGGTGTGCCTATAAAACAATTTATAGCAGCTACAAATAGTAATGATATTGTTCCTCAGTATTTAAAAACTGGCGTTTATACGGCAAAACCTTCCGTACAAACCTTAGCTAACGCTATGGATGTTGGTAATCCTAGTAATTTTGTAAGGATACTAGATATGTTTGATAAGGATAAAACTAAACTAGAAGCAGCATTTGATGCTGTAGCATTTGATGATGATGCTATCAAAGTGGCAATCAAAGAAGTTTATCAGGAAAAGCAATATATCATGTGCCCACATACGGCTACTGGTTATTTAGCAGTAAAAGAGGCCAAGGCAAAAAACCAATTAGATAAGCATGCTTATGTAGTTTTGGCTACGGCACATCCTTGCAAATTCCCTGATGTTTTTGAGGAATTGCACATTCCTTATGAAGTACCTGCACAAGTAGCAGAGCTATATCATAAAGCAAAACATCAAATTGTGATGGATAACAGCTATCAAAACTTTAAGGATTATTTGTTATCGCAATCATAACCCTGAAAGGGTTCAATACTGATAACCATAGGTATATCCTATGGAGATAACCAAGGCGCAGCCTACGGAGATAACCCCAACCCTGAAAGGGTTCAATACTCATAACCATAGGTGCATCCTATGGATTGACACATATACAAAGTCTGAGTGATGGGATAAATGCCCAACCCTGAAAGGGTTTAACACACCTAACCATAGGCGTCGAGCCTATGGATTGACACATATACAAAGTCTGAGTGATGGGATAAATGCCCCAACCCTGAAAGGGTTCAATACTCATAACCATAGGTGCATCCTATGGATTAAAACACACGTACAACCTAGTAAATGATAGATACGCAACCCTGAAAGGGTTTAACACACCTAACCATAGGTGTACACCCTATGGATTAACCCTCTTTTTAGGGATAACCGCTTTGGTGTTACCGCCATTTATTTTAGTAAAGCGATAGCTTAAGGCCGCCATAAAATTACGGGTTCTTTGAAGCGAAAAGCTTTCTTGGAAAAAAGTTTGCCCTTGGGTGATAGAACTAAAATTACGCTCGCTAAATGGGTCTACCATGGTTACGCGGGCACTCATTCTATTCTTTAAGAAATTACGTTTAAAACCAAACTGACTTTCTAAATAGCCATTTACTATGCCCTGTGCAGAAACATTTCTGATATAGTTAAGATTAGCTTCCATGGCTGTAGATTTATCAAAACTATAGCTCATGCCTGCATTAGCTCTTACCGCTATACCTGTATTATTTAAACGCGAATTAGCAGCCGATTCATAACTTACCCTACTCACCGTAAAGCCGGCATTCATATTCTTGGTTTTATCTATTTGGTAATTTGCGAAAGTGTTGAAATTTATAGAGCTGCTATTTCCTAAGTTTAAATAAGTAGTCTCTGTACCATTGGTACCTGCAATAGGGGTTTTAATACGCTCTATAATCCTGCTAGAAATGGCATAACTAATTCTTGGCGAAACCGACCAGCCTTTACCAAAAAAGGTAATATTAGCTTCGTATTGGTCTGTAAAAGAAGGTCTTAAATTGATATTTCCGAAACGGATATTTAAAGAGTCAGAATTATCTATCAAAGGGTTTAGGGCAAAAGCTCTGGGTCTGGTAATTCTTCTGCTGTAATTTAAACCACCACGCATGGTTTTAGAAAAACTCCGGGTAACGGCTAAACTTGGGAAAAAGCTCATGTAAGGTTTAAAATCAGCATTAGGCATATTTTCTTGTATAAAGTTGATATTGGTAAGCTCAGCTCTTGTTCCAGCTCTTATACTCCATTTTTTTATCCTAAATCTGGCTGTTAAATAGCTGGCGTAAACATTTTGCTTAAACAAAAAGGCATTGGTTAAAGCATCATTTACCACATATTCATTCACATCATAATCAAAGCGTTGCGCTAACTGATTTTCGTCTGAGTTGTTAAGGTTGATTTTAAAACCCGTTTCTAAACGCGTATTTAAAAATTTAAAAGTCTTATCGTAATCAAGGTTTAGTTCTAGGTTAGAGCCTACATTGTTGTTGCTATTTTGTTGTAGGGTAGGTTCTGGATTCCTTAAAGTTCCATCTGGTCGGTAAGAAAATCTAGAAAAGTCTCTTAAATCAGTATAGTTATTTCTATTGTAATTGATGCCTACGGTATAATTCTGTTTGTTTTTTCCTCTTAGCGTATAATCGGCATCCATCACAAAATCATAACTATTATTTCCATTAGTATTATTTTGCCTTAATAGATTTCTTTCTATTCTTTCTTCTGTAAGAGATAAGTTATCAGAAAAACTTTCGCTAAAACCATCATTATAACTACCTCTAAGGGTTGCCTTTAAAACTTGTGCAGAATCTGGTTGGTAAGTTATAGATACTCTACTGTCTACACCATCAGTAATACGCTCTGCATTATTTGTTTGGTCGTTAAAAAAAGTAGTATCAATAGCGCCATTAGTATCAAAAACATTATTGGTTCTGTTAGAATTGGCATCAGATAATCTTAAAGCATGTGAATAACCTGCATTGGCATTAAAAGATAATTTTTTGCCTTTTGAAGATAAAAAAGCACCTGCATTATGATTTCCTAAAGTGCCAAATCTGGAAGATAAAGTGCCTGTTAAGCCCACTTTACGACCTTTTTTCATCACAATATTGATGATACCATCGCCATCAGCATCAAATTTAGAAGAGGGGTCTGTAATAACTTCTATACTTTCTAAAGCGTCTGAAGGTAAAATACTCAATAACTCGCCTATACTATTTGCAGAATAATCTGAGGGTTTGCCATCAATAAAAATCCGGGTATTTCTTCTGCCGGCAATGGTAGCTTTTCCATCTATATCCACACTCACCATAGGTACGTTTTTCAAAACATCGGCGGCAACGCTACCCTCACCAGCTATGGTTTCAGAGATGTTATAAACCAATTTATCGTCATGCATTTCAACCACAGGTTTTTGATAGGTTACCACAACCTCATTCAATAGTTTATCATTAGCATTGAGGAGGATATCGCCTAAATCAATCTCGAAACGGGTATCAGTAATGGCTATTTGGGTAATGGCTTTATTCTGATAGCCCACATAAGATATTTTTAAAGTATAGCTACCAGGTTTTAAATTATTGATCGTGAAATTACCTTCCAAATCATTCTGTAATGATTTTGGCGTAGAAACGCTATCGGTTAAGCTTAATGCAGCAAAAGGAATAGGAAGATTGGTTTTAATATCTAAAACTCTTCCTTTAATAATACCTGGTGCATTTACTGGTAAATTTTGCGAAAATACCTGTAAACTAATCGTAATAATAGAAAGTATCAGCCAAAAACGTATAGGTTGAAGCAATTTCAATTTGGTTATTTATAGTGATTGAGTTTTTTAGACTCTTTTATCTGTTAAAGGTTTAAAAGCTTTCTTCGCCCATGCCACCTCCGGTATTTTCTGGTCTTTTGTTATTTCTTCTTTGGTTATTTTCCATTTTACCAAAACGATAGCTAAAGCTTAAATTATACATTTGGCCTTGTCTTCTACGCTCAAATTCTTGTATAAACTGGCCGTTATCTGTTAACATGCCAAATCTTCTGCTGTTAAAAACGTCTTGCAAGTTAAGGCCAATACTTCCTTTTTTATTCAACACATCGTATTTGATACCGGCATCCATGGCAATCATTTCCTTCATTCTGCCTTGCGACATTACCCTTGGAGCCATGTAAAATAAATTGGCTTGCGCCGATAGCTTTTTGGTAATGGTCATTTGCGATGTTAAATTACCATTCCAGTTAAAGCCATCGTTATCATTAATACCTAAACTAGCATCGCCCGTAAAATAGGTTTGGAAGAAGTTTAAGTTACCGGTAATATTAAAGCCTTTAGCAATATCAGCCCTGCTGATTAATTCTAAACCAAAAGATTGATTTCTGGCAATGTTAAACCATCTGGAAATAGTACCTCCATTTTGATCAGGGTTTTGTTGTCTGATACTTTGTACAACATCATTTACCTGTCTGTAATAAAGGGAAGATGTTAAGGTAACAGCTTTCCAAAATTTAGCATAACCAAACTCGAAAGAATGAATGTCTTCTGGTCTTAAATTAGGATTTCCGATTCTGATGTTATACCTGTCTGCAACATCTGGGAAAGGGTTAATTTGCCAGCCTCTTGGCCTGTTTACTCTTCTAGAATAACTTAGCTGTAATTGATTATTTCCTTTAAGTTTTTGAGTTAAAAATATACTAGGATACAGTCTGAAATAATCTAACCTGCCGGGTGCAGAATTTGGCGTTCCATTAATATCTGCTCTGCTAAAATTGGTGTTTAAATAAGCTTGTTCTGCCCTTAAACCAACTTGTGCTCCAAAATTTTCAGTAAATTGTTTTTGATAATTACTATAAACAGCATGTACAAATTCTTCCATCTCAAACAAACTAGTTAAATCAAAATCTCTGTTATAAGAATTGAAATTAGCCACTAAAGTGTCTGATACTTGGTCTTCATCACTATATCTTAAGGTGGTGCGGTAGCCCGCTTCTAGCTTACTGGTTTTAGAAAATGGTTTGATATAATCTAGCTGAATATTAAAATTTCTATTGTCTTGTGCAACATCGTTACGACGGTTAACGCCTAGCCTATCAGAAAGTCCGCCTTGACTATTGAAAAACTGTTGCACAATGTTTTCAAAATCATTTTCATTGCTTTTTCCGTAGGAGAAATTGGTACTTAGTTCCTCACCAGGGTTTTTAAACTTATGGAAAAAATCAACATTTAAATCATAACCATAACCATCTTCTGTATTGATGTTTTCACCTGGTCCGCGGTCTTGTAAATCTCCGTTGCTATTAAAGAAAAACTGGTTAAGCGTTTCCCTAGCATCTTCATTTCCTACGTTAAGATTCCCAGAAATAGCTAAGCTAGTTTTTGGGGTAAAGTATCTTTCTACACCTAGTTTTAGAGTGTTTGTTAAGTCTGATCTTAAAGTGTTTTGGCTAGCAGTAGTAAATGCGCTGGTATTATTGGTGCTCAAAAATCTGGTGTTATTAGAGCCAAAACCAATTCTATCTCCGCTTCTTAAAGAGTAATTACCAGAGAAGTTCCACTTTTCATTTCTAAAGTTTAAACCTGTATTAAAGTTGTAATTATTAAACCTACCTGCAGATGTATTAACATTACCATTAACACCCAAACGCTGGTTCTTTTTAAGTACGATATTGATAATTCCAGATTGCCCTTCTACGTCATATTTAGAAGAAGGATTGGTAATCAATTCAACTTTGTCTATCGCATTAGCGGGTAAAGATTGCAGGATAGCATTAACATCGCTACCGCCAAAAGTAGATGGTTTACCATCAATAAGAATACGCACATTACTTGTGCCTCTTAAACTTACATTACCATCTAAATCTACTTGTACAGAAGGTACAGTAGCCAATAAATCTGCGGCAGTACCACCTTGTGTAGCCAAACTTTGGTCGGCATTAAATACTTTCCTATCTATACCTAATTGTATAACATCTTTTTTACCCGTTACAACAACTTCATTAAGCACAGCATCAGCATTTTTATTAAGTTTTAAAATACCTAAGTCAATTACTTTTTGATTGGTGATGGTAATAGTTCTACTAAGCGTATTATAACCTACAAAGCTAATGCTGATTTTAAAATTGCCTGCCTCATTAATATCGTTAAAAGTAAAATTACCTTCTAAGTTGCTTTGTGTAGCTTTGAAAGGGTTATTATCTGCTTTTAAAAGTTTAATAGTGGCAAAATCTAATATGGCAGAAGATTTAGCATCTACAACTTTACCTTTTATCTGAACAGAAATGGGTGTTTGAGCAAAAATTTGTGTAGTAAGCGCAATAAATACTAAGATTAGAACAAATAATGGAGAGTAAAAACGCATGTTAAGTTTAAGTTTTCTGTTTAGAACTCGAAAGTTAAGCCAGTGTTTAACCAAACCTGCTAAGGTAACCGCATTATTACATAAAGTGCTGCTTTTCAGCAACACATAAAAAAGGTTTTAGGTAAGATTTGTTTAATCAACAGAAACGGTTAAACCTTCCTGTTTTAAGATTTTACGGTAAACTTCCATCTCTGTTAAAGAACCTTCCAAAATAGCACATTTACCTTCGTTGTGTACCGTCCATGCAATTTTATCGGCTTGGTTTTCAGAATAATCCAGATATTTCATCAAGCAATAGATAACGTGGTCAAAAGTATTCACCTCGTCATTCCATAATATTAATCGGTGTACCGTTTTTAAAGAGCTTAAAATCTCGTCAAGGGTAAAGGTCTCTTCTTGTGTTTGTGTACCTGCCATACAAATCATCCTGCAAAAATAATTATTCGTAGTTAAAAGCTTTCAAAAAAAATGATAAGAAATTGTTAGCCAAATATTTTTAGAGTTTTTCAATCTCTATGCGCTTATTCCCTTTTAGGTTTTTAAAGAAACTTGGTGTTAGACCAGTTACTTTTTTAAACTGGCTACTTAAGTGCGCCACGCTGCTATAATTTAGTTGGTAAGCTATTTCAGAAAGCGATAATTCATCGTAAATCAATAGCTCTTTAACTTTTTCTATCTTTTGGGTGATGAAGTATTTTTCTATTGTAATGCCTTCTTTCTCAGAAAATAAATTACTCAGGTAACTGTAATCGTGTTTCAATTGTCTACTTAAAAAATCGCTTAAGTTTATGTGTAAGGCTTCCTTTTGGTGATGTATCAATTCAATAATTTGTGTTTTAATAGCATCAATCAATTTGCTTTTTTTATCATCAATAATTTCGAAACCTAAATTTTCTAACAATAGCGTCCTAAACGAATAAAAAAGGAGAAAGGAAAGTTTTAACTCATCGTTACCTTTGAGGTTGCACAAAAACAAACCCTTTCTCAATGGTAAATGTAACACTATTCTCCCAAATCATATCAAAACTTGAGCGTTCAAAGTTCAACAAACTGGTATCTACATCTCAGAGCGACAAACATAATAAAGGTTATACAAGCTGGACACATCTAGTATCGATGTTGTTCTGCCAGTTTGCCAAAAGCCAATCGGTACGTGATATTAGTAACGGTCTTCGTTCAGCTACTGGCAACCTCAATCATTTAGGTATTCAAAAAGCTCCATCTAAATCTAGTGTAAGCTATCAGAACAAGCACAGGGACTATAACATCTTCAAGTCCTATTATTTCATACTGTTAGAAAGTTTGGGACAGCAGGCAGGCTTTAAACAAATAAAGTTCAGGATTAAGTCCAAAATCTTCCTGTTAGACTCCACTACTATCAGTCTGTGTCTTTCTCTATTTGATTGGGCCAGGTACAAAACAGCTAAAGGAGCGGTTAAACTGCATACTCTGCTTGATTATGATGGCAATCTACCAGCATATGTCAATATTACCAACGGCAAAACTGCGGATAACAAAGGAGCTTATGATGTGCCTTTACACAAAGGAAGTGTTATTGTTGCAGACCGATTCTATAATGACTTTGCCCTGCTGAATGTTTGGGACAGCAACGGCGTATTTTTTGTGATCAGACATAAAGAAAACCTCCAATATACTACAGTTAAGGAAAATATATTGCCGGAGAACAGGCATAAGAATATCCTGATTGACGAGATTATTGAGCTTAAAACCACAAAATCAAAGGACAGCTATCCCAAAAACTTAAGAAGAGTGGCTGTTTGGGATGATAAAAATGAACAAACTATAGAAATTATTACCAATCAAATGTATTGGACAGCAAACACCATCAGTGAGCTTTATAAAAGCAGATGGCAGATTGAAATCTTTTTTAGAGAGATCAAACAGAACCTGCATATCAAATCATTTATCGGAACCACAGAAAATGCCGTGATGATACAGATATGGACAGCGCTAATTACCATCCTCATCCTTAAAGCACTTAAAGCAATGGCTAAATATGGATGGCAGCTCTCCAACCTTATCGCATTTATCAGACTTAACATATTTGTGAAAATAAATCTACAGAATTGGCTCGATAGGCCTTTTGAAGAACCCGATGAGCTAAAAGATAAACAAGTTATTCAAGGGGTTCTTTTCTGAAATCTATTTTTATCTCATAAATTTTAAGCTATTGCGTTACTTTTGATGTTTTCATAAACGTTTAGGACAGTATTGATTTTCTAACTCTAATTTTAGGGTATTTACTTGTTTTTCTGTTGGTGCTTCTTTCAAATGTACTTCGCCAAGCAGTACTTGTTCGGGCTGTAAATTTAGTTCCTGAAACACCTGCTCAACCACCATTTTACAGCGGCTGCAAACCATATTTTTGATGTAGATGACCATAGTTGATGCTCTTATTACAAATATGCTATTTTATAATGGCTAAAATGATAATTAAATAGGGCTATGTTAAAGGGATATATTATTTTTGGGCCATGAATATCCTAATCCTTGGTTCTGGCGGAAGAGAGAGCACCTTCGCCTGGAAAATTTCTCAAAGTCCTTTATGTGAAAAATTATTTATTGCACCCGGAAACGCCGGTACACAGCAATATGGCAAAAATGTAAACATAAAAGCTACAGATTTTGACGCTATCAAAGCTTTTGTACTTCAAAATGAGGTAAACTTAGTATTGGTTGGACCAGAAGAACCCTTAGTAAAAGGTATTCACGATTATTTTTTAGCCGATGAGGATTTAAAAAACATCCCTGTTATAGGGCCTAAAAAAGATGGTGCACAGCTAGAAGGCAGTAAAGATTTCTCTAAAAACTTTATGGAGAAATATAAAATCCCAACTGCCGCTTCTCATACTTTTACAGTTGATACTTTAAAGGAAGGTTTAACTTATCTAAAGCACCATCCACTACCAGTAGTTTTAAAAGCCGATGGCTTAGCGGCTGGTAAAGGCGTTTTAATTTGCAGCACTTTAGAAGAAGCACAAACAGAATTAAAACTGATGCTGGAAGATGCTAAGTTTGGCGAAGCCAGCTCTAAGGTAGTGATAGAAGAATTTTTAACAGGTATAGAGCTTTCTGTCTTTGTTTTAAGTGATGGTAAAGATTATATCGTTTTACCAGAAGCTAAAGATTATAAGAGAATAGGCGAAGGAGATACAGGTTTAAATACAGGCGGAATGGGTTCTGTATCGCCAGTACCTTTTGCTGATGCAACTTTTATGAAAAAGGTAGAGGATAGCATTGTTATCCCTACGGTAGACGGATTAAAAGCAGAAAATATTGACTACAAAGGCTTTATATTTATTGGCTTAATGAATGTAAACGGAGAGCCTTATGTGATAGAATATAATTGCCGTATGGGCGACCCAGAAACAGAAAGTGTTTTCTTAAGAATAGAAAGCGATGTAGTAGAGATGCTAAAGGCTGTTGCCGAGGAAAGAATTGCCGGATATGAGTTAAAAATCTCTCCGAAAACAGCTGCTACTATCGTGGTTGTTGCGGGTGGTTATCCCGGCGAATACCTTAAAGGAAAAGCTATTACAGGGATAGAAAACGTAGAGGAGTCTATGGTGTTTCATGCTGGTACCGAATTAGAAAACGGAATCATTAAAACCAATGGAGGTAGAGTATTAACCGTTAGTACTTTACAGGATGATATTTTTACCGCTTTACAACAAGCTACCGCAGATGCTGGAAGAATTTACTTTGACGCTGCTAATTTTAGAAAAGATATAGGTTTTGATTTGATATAGAGGTATAAAATCAACAATTTTACCCATATTTACTCAACATTACACAGTGTTGGGATTGTTAATAAAATCCACTGTTAATTTTACAGTGGATTTTGTTGTATAAGGGGGTATTTTTCTTTGAAAATTATCCACAATAGCTCAATCTGGCACAATATTCCCTCCTGTGGGGATGATATACATACTAAATGATTAAAGGGTTTAAAATAGTTTTTACATTTCTACTGATACTAAGTATAGCTGGCTGTACTAGTAAAAGGTATGAATGGGTAAAAGTTAATCCCGAAAAGCTTCATTTAGCCAAAACAGCTAAACCTTATAGCGAAAGTGTAAGAAGAGTTAATATTTATATCAATGCCAAGCACAAGGCAGAGTTGCTGGTTTATGAGGACGCTGATACTTTCTTACAAAAGAATATAGTTCCTTCTGCTCAGCCTATTTCAAAGGTTAATCGACCAATAAAACAAAATAAAATCGCTAAGCTTAGTACTACAAAGAAGATTGTGGCTAAGAAATCTCCAGCTATAGCGCTAGTAAAACCAGCTCCAGCTGTTAAAGCAAATAAACAGGTTAAGCTCACTAAGCCAGCAGTTAAAGAAAAAACTGATGAAGAGGAAGCATTATCTAAATTAAATAGTGCCTTAATCTTACCAAAAAAGAAGCCTAAGCAAACAATTCAGCCAAAAGAAACAGCAGTTGAAAGTGTAACTCAAAAAGAGCAAGCAAGGCAGCAAGCTGGTGTTTCTCCAATGTTTTCAGATCAAGCTGATAGCAAAACACAAGAGGCAACACAAAAAAGTCCTAAAGCGGTAGAGGATCAAGAAGTAACAAGTTCTCCCGCAGAAGAAAAGTTAGAAGAAACTCAGGCAGACAATTTAAATAATCCGGAAGAAGAAGTTAAAAACAGTGAAGAAGGAGCCTTCAAGCGTAATAATTACATGTGGGTAGGCTTAGTTCTGATTATTATAGGTTTGATTATTGGGCTTGTATTTGGCGGCATGGCTTATTTCATCTCAGTGGTAGGTGTTATTTTTCTTTTGATAGGCTACTTCTACAAGGTATAAACAAAAATGTCTGAAGATTTTCATCCCCAGACATCTTCAACTTATTTCTTATCAAAAATCTCTTTGAGTTTATCTTCTAAAGCTCCGCCTCTTAAATTTTTAGCTACTATTTTACCGCTAGGGTCTATCAAAAAGTTCTTAGGAATAGCATCAATACCATAAATTTTAGAAATCTCTGTAGTAGAATCTATCAGTTGAGCCCACATCAAATTATCTGTTTTAATAGCTTTTTGCCATGCATTTCTATCTGTATCTATAGAAACACCTAAAATAGTAAAGCCTTTATCTTTATACTTTTCGTAAGCGCTCACTACAAAAGGATTTTCTTTGCGACAAGGGCCACACCATGATGCCCAAAAATCTAATAATACATATTGACCTTTGTAGGATGATAATTTAAGCGGGATACCTTCAGGTGTTTTTTCCTCAAAATCTGTTGCCATAGCGCCAATGCCAGTTACCTTCGCAATGTCTAATTTCTGCTTGATAACAGCAGCTAAAGCATATTTCTTAACCTTATCTTGTAAACCACTAAATAAGCTTTCTGCTTGGCTATACTCCATATCATCAATACCCAAATCCTGATTAAAAGCATACAAACTGATGTAAGATTGAGGATTTGCTTTTATGAAGTTGATGATTTGCGCTTTTCTCTCTTCCAGCAGATTTAAATAGCGCCCTTGGAAACTTTCAATGGTTTCTTGTTTGGCTTTTTTCTCTGGTGCTAAAGCTGCAAACTCTTTATTTAAAGCAATTAATTTGCTTTCTGATGCCTGTGTAGCAGTTTTGTAAGCCACATCTTCCTTAAAAATGGTTAAGCCATTTACCTTAGCTTGTGCAATAGAATCTTTTGCGGTAAGGGTGGCATTTCCTGGCTCAATAAAAAAGCGGTAAACGTCTTTTGGTCCTTTATCTTTTAAAGCATTTCCTTCATGCTGTAATAGTAAAACGGCAACACTAGGTTCTTTTAAATCAAGATTGAAACTAAATTTCCCGTTATTAACCACGGCCGAATCTATCACCTCTGCATTATTTTGGATATGGATAAAGTATAGCTTCTTATTTTGACTCGCAGCAGAAAACTCGCCTTTAAGGCTAAACTGTGCAAAAGCTAAAACCGGAACCTGCAATAGCAAGCCTAAGAGTATTTTTTTCATGCTTTTTAATTTAATTTTTGATATGTGCGCCACCATAAATCGGGCATTTCTCCGCTAACGGCCAATTGATAATCTTCATATAAGCAAGGCACAAAATGAAACCTTTCATTTTTAGAACCTGCCGATGGATAAGGAACTTGCATCCACCAACGGTCTGTTTTTTTACTTTTAACAAATATCAACTCATGTCCGTCTTCTTGTAAACTGGTCTTATATACGATATAGTCTGATTTAGGGTTCATCGGGAAATCTTTCTTGCGGTTATAAAAACCATCTAAGAAACACCAAATCATTTGCGCCATCAACATCGCCGATTGCCCGTTTTGGTCATAAGCCGGGTTAAATTCGTAAAAACCTATAGAACTTAATTTATCGCTATAACCTGCGTATCTGCAAAGCTGACAAGCTTCTTCGCCGTAAAAACCATTAGGTGCAGCATTTCCATTAGCTACCGCATCAGAAGAACGTATGCTACTGATATCAAAACTGATCATATTAGCATTTCTGATAGCAGGTTCTGCCAAGTGTACTGCTCCGCTAATTTCTCCTAAGCGTTGTGCATCAAAAAACAGCTTATCCATCACCCTTAAACTATCCTGACTAACAAAATAAGTTTGGTAGCCTAGGTTGCTAAAGTTGAATAGGTAATTAGGCTGGTGCAAGAAAATCTTGTTCAGGTAGGAAATAGCATCCGTAGCTACAGCCTCATCTTCCTCAGCCTCATTCATATCAAAATGAGAATCTATCACCAATAAATCTACCTTTTGCTCTAAATCTTCATAACCTAGGTATTGGGCATAGGTTAAATCTTGGCTTCCGCCGATGATAAGGGGTAAAATATTTAGCTTTATAAGCTCGGTAGTAACAGTTTTTAAGGCAATATAAGTGTCTGATAACTGATGGCCGGGTAAGATATTCCCTAAATCAACAATTTTAGATTTATATGCACCTTCATTGAGGCTGTATAATTTCTCGCGAATATAATCTGGCCCCAAGGCACAACCTTGGTTGTTGATAGCGCCTCTATCATCGCAAACACCAATAATGGCTACATCAAAACTAGCATCTTCTAAAACAGGAAAATCTGTTTCATAAGCAGTAATTTTCATACCTAAATGGCTGGTATAAAAACCAGTTTTAGGCTTAAGTTTTTCAATATTGATGGGAGAGAAAAAATCTGCTAAAGACATATTGTTGGTATAAATCAAATCAAATATCTAATTTTTATGTTAATAGATATTAAAAATTACGATTAAACATTTAATATCATCTTTAGCTGTTATTAATCAGTTAAGAATATTTAATTTGCCTTTTTAAATTAGCGGCATGATTTTAATTACAGGAGCAACAGGATTTTTGGGCGCACAATTAACCAAGCAACTTTTAGCAAAAAGTATTAAAGTTAGGTGTATCAAAAGAGCGTCTTCTGTAATACCTGAAGTTTTAAAACCTTATGAAAGCCAAATAGAGTGGTTTGATGCCGATATTTTAGATGTTTCTGATTTAATAGATGCCTTTGAGGGCATTACCCATGTTTACCATTGTGCGGCTTATGTTTCTTTAAATAATTACAATGAAAAGGAAATGATGGCCATCAATGTTGATGGAACAGCTAATGTGGTAAACCTATGTTTAAGCTTTGGCATAACAAAGTTGGTTTATGTAAGTTCTATTGCGGCATTGGGGCAAGTTAAACCCGGCGAAACCATCACAGAAAATAATTATTGGGATGCTTATGATAAAAATGGCGCTTATGCTATCTCTAAATACAGGGCAGAAATGGAGGTTTGGCGTGGTGTAGAGGAAGGCTTAAAAGCAGTTATTGTAAATCCTTCTGTTATTATTGGTGCAGGTATTGGCAAACAAGGCAGTGGTAAAATATTTGAAACCGTAAAAAAAGGTTTAAACTACTACACATCAGGTGGTACAGGCTTAGTAGATGTAGAAGATGTGGCCTGTTTAATGATTAAGCTGATGGAGCATGAAGTGATAAATGAGCGTTTTATCATCAATGCAGAAAATTACAGTTTTAAACGTTTATTTACAGAAATTGCTGTGGCCTTAAACTTAAAAGCCCCAGAAAAAGAACTAAAAGAATGGCAAGCAAGATTGTTTTGGCGCTTAGCTTCTTTTTTACGTTTGCTTAAAATTAAAATACCTGTGGTGTCAAAAGATTTGCTAAAAGCAGCATTTCAAACCCAAGAGTATAGTAATCATAAGGTTTCTTCCTTGCTCTCTTATCACTTTACCCCGGTAAACATGAGCATTACCAAAAGTGTAAATGGTATAAAATCATTTTAATTTCTCTAATTTTCCATTTTTTTAAAATCATTTATGCATTTTTGGGCTTAAAATTTTTTAAGCTTTGAATCAGTATTTTATCATAGATTTCGATAGTACTTTCACACAGGTGGAAGCATTAGATGAACTGGCAAGAATATCTCTAAAAAATCATCCAGATAGAGAAGCCATCTACAAAAAAATAGAAGACCTTACCAATTTAGCTATGGAAGGTAAACTTTCTTTCTCCGAAAGTTTAGAAGGCAGGGTTAAATTATTAGAGGCTAATAAAGACGATTTAAAAAAGCTGATCAAACATCTAAAAACCAAAGTATCTTCTTCTTTCTCTAGAAATAAGGTGTTTTTTAAGAAGCATGCTAAAGAAGTATTAATCGTTTCTGGTGGTTTTAAAGAGTTTATTACACCTGTAGTAACGCCTTACCATATCAAAAAGGAGAATATTTATGCCAATACCTTCATCTTTGACGAGCAAGGTAAAATCATCGGTTACGATAAAGCTAACCCACTATCAGAAGAAGGGGGTAAAGTAAAACTTTTACAAAGGATGTCTTTGAAAGGTGATATTTATGGTATTGGCGATGGTCATTCTGATTTCCAATTGAAAGAATCGGGCTTAATTAAAAAGTTCTTTGCTTATACCGAAAATATTGAGCGTAAAGCAGTTGCCGAAAAGGCAGACCATGTAACCCCAAGTTTTGATGAGTTTCTTTATGTAAGCGATTTACCAAGAGCTATCTCTTACCCTAAAAACAGAATTTTATGTTTAGTGGTAGGTAATGTGCCAGAAGAAAGTATTCAATTACTTAAAAAGGATGGTTTTTCTATCAGACACAAAGAAACCTTTGAAGATAAATACGTACAAGATGTAGGGATGCTGCTTTTGGCAGATGGTGAGAAGGTAGATAAAGCTACACTTAAAAAAGCTGTAAAACTTAAAACCATAGGCTATTTTGGTAATGCAAAAGGCAATATAGATTTTGATGTATGTACCGAAATGGGTATTGTAGTTTTTGATAGTGTAAAGAGCAATCTTACCCACAAAACGCTTATAGCTCGCCGTATGGCCGATTTTATCAATACCGGAACCACCTACATGAGTAGTAATTTTCCTAATCTGCAATTGCCAAAAATTGCAGGTTCGCACAGGCTTATCCATATTCATGAAAACGTACCGGGTGTAATGGCTAAAATCACCAAAGTATTGGCTAAACACCAAATCAATATTGTGGGGCAGTTCTTAATGACCAACCCTTTAATTGGATATGTAATTACCGATACCGATACAGAATACGATAAAGCCTTACTTAAAGAAATGCGTAAGGTAGAAAATACCATTAAGTTTAGGGTCTTGTATTAGGCCCTAAGCTGCTTTTTTAGTTTCAAGTAGTTCATCACAAAGTAAATAAACAAGGCAACTATACTTAAAAGCATTAATATGTAGGCGAAAGCACCAATATGAACCCACAATTTAGCTCCCGGAATATGGTTGAATTTATAGAAGAAACCAATCAAGAAAAAAGTTAATCCTACTAAAAAGCCAGTTAAAGCAGTATATTTAAGAGTTTTCATAGCTAAAAATTTATTCTAATTTAATAAACATTCTTTTTATGAGCAATAGCCAAACATTACCCATTCTAAATGCTGAAGAGATAAGAGTTTTAGGTGCTTTGATGGAAAAGAGTAAAACTACTCCAGATTATTACCCTATGACGCTGAATGCTTTAACAGCAGCTTGTAATCAGAAGACATCGCGTAAACCTGTTGTTGCTTATGATGAAGAAACGGTAGTGATGACTTTAGACTCATTAAAGAAAAAGGGCTTAATTTCTACTGCAACAGGTGGTGGTAGCAGAACGGTAAAGTACAAACATAATTTTGCTATTGTTTTTCCGGTTGTGCCACAAGAAGTGGCTTTAATTTGCTTGTTGTTTCTACGCGGTCCGCAAACACCTGGCGAACTAAATACCAATTCTGGTAGATTATATGAGTTTGAATCTATAGAAGATGTACAGCAAACTTTAGAAAAACTAGCTACAGAAGAACCTGCTTATGTAGTACAATTACCCAAAAGAGCCGGACAAAAAGAAGCCAGATATGCCCATCTATTTGCTGATGTTGTATTAGATGAAGATGATGATTTACCTGAGGAACCTGCTCGCAAATCAGTTGGTGAGTTGGAAGCTCGTTTAGCTAAAGTTGAGGATGAACTAGCCGAGTTAAAAGCTGCTTTTGATAAGCTGATGAAAGAATTGATGGATAGTTATAGCGTAGTAAGTAGTTATAAGTAGAAAATACAGAGTATAAAGATGCCTAAATAGCCGATATTGATGTACAAGAGAGTATAGCGTAGAAATGGCCTCCCCCTACGCCCCTCGAGAAGCTACCGTGTACCCACAAAAAAGGTAGATATTTGGATAATGGAAAGATCAACCTATTCGGGATATTTTGGTGATAAGCGCTTAGAACACCGGGGTTACATGCTTCGTCAGCGTTTGTTCAGTAGTTGTACCCAGAGTATTCAGGCCCTATCACTTAATAGAGCAGAACAAAAAGCATATTACCGTTTTCTACATAATTCCCGTACAGCTGAATCAAAATTAATAGCAGAACTGATGAAGCGTTGTTCTATACAGAGCAAAGGAAGAGTGGTTTTGTCTATCCAAGATACCACAGAAGTAAACCTAAGTAGGCATAAAGGGCGCTTACAAGCATGTAGCGGTCTAGGAGGGATCGATGACAGTAAGGGAATCGGCTTTAAGCTTCATCCTTCATTAGTAGTAGATGCAGAAACTTGTTTTCCATTAGGTTTTTCCTCTATCAGGATGTGGGGGCGTGAGCAGGATAAGGGAAATAAAACCGAGCGCAGATACATGAATTTACCGATAGAAGAGAAAGAATCCTATAAATGGATAGAAGCCAGTAAGCAGAGTCAGGAAACACTTCATCAGGCAAAAGCTGTTGTTATCGTTCAGGATCGTGAAGGTGATATTTTTGAACAGTTTCTTCGGATACCTGATGAAAACACCCACTTACTTATTCGTTCCTGTTTCAACCGCCAAACCAATGATGAGGAAGGGAAACTCTGGGATCAGCTTTCTGCTTCAGAAAAACTGGGTGAATATCAGATTAAAGTGGATAGCGACAGTCATGGAGGTACTCCAGCCCGGCAAGCAAGCCTGGAGGTTAGAAGTATAAAAACAAATATCCGTCCCCCAAAAGAAGGTAAAGGTAAATGTGTTCAAGTCTATGCTGTTGAAGCTATGGAGGCATCTACAGAGAATTATCAGGGAATACACTGGCGCTTACTAACCACCTGGCCAGTAGAAGATTTTGACCAAGCCCGTTTAATTATTGAATGGTATAGCTGGCGCTGGGTGATAGAAGAGCTTTTTCGCATGCTCAAAAAAGAAGGTTTCAATATAGAAGGAAGTGAACTTGAAACAGGGTGGTCCATCAGAAAACTTACAGTGATGCTACTGGATACCATTATGAAACTGATGCAGATGCATATAGCATATAGTGAACCCGAAGAAGCCAATATACCAGATACAGATTTAGTGTTCTCAGAAGATGAACAGGAATGTCTGTTGGCACTGAACAAGGCTAATGAAGGAAAAACACAGGCTTTGAAAAATCCTTTTCAAGCAGGAAAACTCAACCACGCAGTATGGATTATATCCAGAATAGGTGGCTGGAAAGGATATAGGTCTCAAAGAAAACCAGGTATGACTACTATGTTCAAAGGATTAAACAAATTCTATAATATTTATGATGGTTGGATACTCCAAAAAGATGTGGGTACACGGTAG

Protein sequences of DBSCAN-SWA_3

>NZ_CP043329|3386789:3444875|3410247_3411135_+|WP_149075525.1|DBSCAN-SWA
MQFGKVEDPSIINFSLPADAPETKDLLKNTSKSTFEAYVGCAKWNKADLKGFYPRGTKDELTYYATQFNSIELNATFYNLPSSAQVSSWRDKTPDDFKFFPKITNSVSHYRRLIDVKEPVTLFCDAISHFEEKLGMAFLQLHDNFKPKDFDRLKTFVEDFPKVIPLAIEVRNEEWFTNKAIADELYQLLKKHHITNVLVDTAGRRDMMHMKLSTPIAFIRYVGANHESDYSRLDEWVKRIVDWKAAGLQKLYFFVHQNVELASPLLSAYFIEKLNKAIGIKLHIPVMATENPTLF
>NZ_CP043329|3386789:3444875|3394091_3394925_+|WP_149075510.1|DBSCAN-SWA
MEIRKAERKRAKIKMALQGSAGSGKTFSALLIAHGISTDWSKIVVIDLENNSADLYSHFGHYNVLPLEQPYSPEKCIQALELCEQAGMEVIIIDGLTPCWEYLLDLHANMSGNSFTNWSKITPRQNALVNKILSIQSHVISTIRVKQDYVLNNKDGKIVPEKVGLKAIQRDGLDYEFTIVLDIDNKHHAVASKDRTTLFMGKPEFTISRKTGEDILKWCNEGIDDTSNILELIKNANSIEVLKDIYFSYPDYQNSLSKAFASRKEALNKLEPFNQKT
>NZ_CP043329|3386789:3444875|3391493_3393455_+|WP_149075508.1|DBSCAN-SWA
MNLDIKEEAKHLLITEEKKGVLELTIKDNSKKLGEILNFLPHGIIDKTVTGIGATTLEIYSKRNSIIVVPLKIIAASKVEQHPENCYYVGSAINNFQTFGEEAFDLFLTNDKIPYKNVIVVAESLPKVIKTIGEDVYKNYFLLIDEINTIQEDSKFRETIENCLDIYLKFPPQSRAMVTATMINFSHPEIAKEQKTTINYEEQKPNLIDEFIMSYNTLGVCIDLIEKLLKEHQDAKIVIAYNSVIGSKILAEELVLSNPENAKNVSILCSKSNKKKAGVFYAELTGLKYPSKINFITAAYFSGYDIEEQYYLINLIDENEIFSKISINAVRQIAGRAREGLHKHYIVYPYSENEEELIEYVDEKQLLDLAKVELKSIECIENNFKEYPFFKTTMLDIHSAVIDNGGYKGFKLIRRNIENEINISYFNIDSYLEHQKTQYEEHASYNSFLKSLSNSFSVLHVLNLQSHHEFSKVKESNLDVDQSIKTAIENLQNITTDNEAYYLSVKAEDNIQKKVYFIYDKLSKFYYEKETLLDKIAEVAKKNSKAFNILKSEVTHKSLPPYHPLKKFIFEYFKEGVIYKSSEILELLNKVHALASTNHKKIDSELKAVEIFNCYFETVRKKYNNGYLLKNYIKQEDYLDTVINRDENNIFSY
>NZ_CP043329|3386789:3444875|3403195_3403369_+|WP_149075521.1|DBSCAN-SWA
MKIIWTNFAIENLKAITKYYTKVAGKSIAYKIKTEIFKSTKQLKHYPDSGQEEISLK
>NZ_CP043329|3386789:3444875|3420834_3421293_-|WP_149075536.1|tRNA|DBSCAN-SWA
MRAVIQRVSQASCTVNGEITGKINTGFLVLLGVEEADTLEDLTWLAQKIVNMRIFNDENGLMNKSLADVDGRILLISQFTLFAQTKKGNRPSFIRAAKPAQAIPLYEKMIAELAQLSNTKIETGIFGADMKIELLNDGPVTIMMDTKDKDRH
>NZ_CP043329|3386789:3444875|3401009_3402386_+|WP_149075518.1|DBSCAN-SWA
MKKLLLFGLLIACSFNLKAQTLYDFNTTGDLEKYFQKSGTTTGVTQTTGTGLNASGSINVTQGINEIFTTKQGYSNGGIGAIYTFSTYFKSEGVNGYGGVGFTNAPGRTRGIYANLDIGLGISVHGGGFVWHNNTTSIDGIWTAGGVVNSTIADLLGAGSPDKWFKVILMITAKANSVFDLRVEVYPAYATGALISNSPAAVQTTTFTNTNLANTSILHSYFGFAGNRITNFDDYSMSLQGSSVIDAGTPVVLGTAALSGSTINLSGNVTDERNSTVSQKGFVWSKTVADPTTADTKIIASTGGLGTYSAQITDVTAGTYYVKAYAINAIGTSYGALQTITISVLPVSLISFTAKAQNNSVILDWSTSSEQYNSHFKLSYATDGANFTLLKHVSASINGNIKNAYSFAHLSPANGANYYLLEQVDLDGTVKDLGIKAVNFSLSKTTQVVFYPNPPKMR
>NZ_CP043329|3386789:3444875|3402388_3402577_+|WP_149075519.1|DBSCAN-SWA
MNFEKDFYTTAKLIDLQGKILQKRNISIADTQLTFDLKSLDAGNYLIQLEGKGTNVQKVVKE
>NZ_CP043329|3386789:3444875|3435272_3436547_+|WP_039454718.1|DBSCAN-SWA
MNILILGSGGRESTFAWKISQSPLCEKLFIAPGNAGTQQYGKNVNIKATDFDAIKAFVLQNEVNLVLVGPEEPLVKGIHDYFLADEDLKNIPVIGPKKDGAQLEGSKDFSKNFMEKYKIPTAASHTFTVDTLKEGLTYLKHHPLPVVLKADGLAAGKGVLICSTLEEAQTELKLMLEDAKFGEASSKVVIEEFLTGIELSVFVLSDGKDYIVLPEAKDYKRIGEGDTGLNTGGMGSVSPVPFADATFMKKVEDSIVIPTVDGLKAENIDYKGFIFIGLMNVNGEPYVIEYNCRMGDPETESVFLRIESDVVEMLKAVAEERIAGYELKISPKTAATIVVVAGGYPGEYLKGKAITGIENVEESMVFHAGTELENGIIKTNGGRVLTVSTLQDDIFTALQQATADAGRIYFDAANFRKDIGFDLI
>NZ_CP043329|3386789:3444875|3430284_3432777_-|WP_149075939.1|DBSCAN-SWA
MRFYSPLFVLILVFIALTTQIFAQTPISVQIKGKVVDAKSSAILDFATIKLLKADNNPFKATQSNLEGNFTFNDINEAGNFKISISFVGYNTLSRTITITNQKVIDLGILKLNKNADAVLNEVVVTGKKDVIQLGIDRKVFNADQSLATQGGTAADLLATVPSVQVDLDGNVSLRGTSNVRILIDGKPSTFGGSDVNAILQSLPANAIDKVELITNPSSKYDVEGQSGIINIVLKKNQRLGVNGNVNTSAGRFNNYNFNTGLNFRNEKWNFSGNYSLRSGDRIGFGSNNTRFLSTNNTSAFTTASQNTLRSDLTNTLKLGVERYFTPKTSLAISGNLNVGNEDARETLNQFFFNSNGDLQDRGPGENINTEDGYGYDLNVDFFHKFKNPGEELSTNFSYGKSNENDFENIVQQFFNSQGGLSDRLGVNRRNDVAQDNRNFNIQLDYIKPFSKTSKLEAGYRTTLRYSDEDQVSDTLVANFNSYNRDFDLTSLFEMEEFVHAVYSNYQKQFTENFGAQVGLRAEQAYLNTNFSRADINGTPNSAPGRLDYFRLYPSIFLTQKLKGNNQLQLSYSRRVNRPRGWQINPFPDVADRYNIRIGNPNLRPEDIHSFEFGYAKFWKAVTLTSSLYYRQVNDVVQSIRQQNPDQNGGTISRWFNIARNQSFGLELISRADIAKGFNITGNLNFFQTYFTGDASLGINDNDGFNWNGNLTSQMTITKKLSAQANLFYMAPRVMSQGRMKEMIAMDAGIKYDVLNKKGSIGLNLQDVFNSRRFGMLTDNGQFIQEFERRRQGQMYNLSFSYRFGKMENNQRRNNKRPENTGGGMGEESF
>NZ_CP043329|3386789:3444875|3400446_3400626_+|WP_149075517.1|DBSCAN-SWA
MSIQTYSLNPFCTHPKGVGKSVKDKWYVYFYYSKIQGVRKLYRSYTDLNNMHQHAYPSL
>NZ_CP043329|3386789:3444875|3433764_3434937_+|WP_149074277.1|transposase|DBSCAN-SWA
MVNVTLFSQIISKLERSKFNKLVSTSQSDKHNKGYTSWTHLVSMLFCQFAKSQSVRDISNGLRSATGNLNHLGIQKAPSKSSVSYQNKHRDYNIFKSYYFILLESLGQQAGFKQIKFRIKSKIFLLDSTTISLCLSLFDWARYKTAKGAVKLHTLLDYDGNLPAYVNITNGKTADNKGAYDVPLHKGSVIVADRFYNDFALLNVWDSNGVFFVIRHKENLQYTTVKENILPENRHKNILIDEIIELKTTKSKDSYPKNLRRVAVWDDKNEQTIEIITNQMYWTANTISELYKSRWQIEIFFREIKQNLHIKSFIGTTENAVMIQIWTALITILILKALKAMAKYGWQLSNLIAFIRLNIFVKINLQNWLDRPFEEPDELKDKQVIQGVLF
>NZ_CP043329|3386789:3444875|3426085_3427390_+|WP_149075540.1|DBSCAN-SWA
MKLYSTKNHHLSVDFKTAVFNSLPADNGLYMPTTIPVLDENIIAGWDKKSLPEIAFDLAYALLKDDISAEALKAIVDDAANFEAPLHPLADDVFILELFHGPSLAFKDFGGRFMSRIMAHFLKEEEKEIRILVATSGDTGGAVALGFLNVPGIKVTILYPKGKVSLIQELQLTTNGNNIEAVEIDGTFDDCQAMVKQAFHDEELNAKFNLTSANSINISRLIPQMFYYANTYARLKQQFEHITFVTPSGNFGNIAAGMLASKMGVPIKQFIAATNSNDIVPQYLKTGVYTAKPSVQTLANAMDVGNPSNFVRILDMFDKDKTKLEAAFDAVAFDDDAIKVAIKEVYQEKQYIMCPHTATGYLAVKEAKAKNQLDKHAYVVLATAHPCKFPDVFEELHIPYEVPAQVAELYHKAKHQIVMDNSYQNFKDYLLSQS
>NZ_CP043329|3386789:3444875|3415096_3415789_-|WP_149075529.1|DBSCAN-SWA
MPSFNHRSTALEIMDDFSLDQQAIHPVLKELEVINQLLGGFQVFYNAFKKLPIRNKDIICDWGCGGGDSLKVLKKYFHKRKIYPHFIGIDATPSAISFAKAHHETADIHFRLADVLEEPFLSEEFDYVISSLFTHHFNNDEWKQLVARMLYTSKKAVIINDLHRHWFAYYSIGWLTQLFSKSPMVKHDSKLSVLRSFTRKELQTLLAQMGIKKYSIKWMWAFRWQIIIYK
>NZ_CP043329|3386789:3444875|3394927_3395890_+|WP_149075511.1|DBSCAN-SWA
MELLTINPPPILKQSSQKSFIVANTLASSYQEIRNNHIIPVFIKDNEPVISHADFIDVSNEIVHHVFQNETILSPSIRLSHPIKGRVPEAKNKPANQLLEEEKTIYYERMAFVIEVPTIRDTVSGNQLNLTIGGVKSYNLDNLYSKKGTDEHFKIFIGFENKVCTNMCVWSDGFIADLKVRSIHELTDAILNLITNYNAKQHLDNLNKFTNYTLTENQFAELIGKCRMYNYLPQNAKQEIQQLLFGDTQINSVAKDYYNDKSFCRSANGDIDLWRFYNLLTGANKSSYIDTFLDRGLNAYEFTNSIVNALESPKSNWFLN
>NZ_CP043329|3386789:3444875|3411146_3411509_+|WP_149075526.1|DBSCAN-SWA
MENFESVEAYIAHFPEEVQNLLKQIRVIIKRIAPDSVEGISYGMPAYKLHKKPLVYFAAFKKHIGFYATPSGHTAFSVELAAYKQGKGSVQFPLNKPIPYALIEKMVAFRVEENRAIRYR
>NZ_CP043329|3386789:3444875|3438770_3439955_-|WP_039454722.1|DBSCAN-SWA
MSLADFFSPINIEKLKPKTGFYTSHLGMKITAYETDFPVLEDASFDVAIIGVCDDRGAINNQGCALGPDYIREKLYSLNEGAYKSKIVDLGNILPGHQLSDTYIALKTVTTELIKLNILPLIIGGSQDLTYAQYLGYEDLEQKVDLLVIDSHFDMNEAEEDEAVATDAISYLNKIFLHQPNYLFNFSNLGYQTYFVSQDSLRVMDKLFFDAQRLGEISGAVHLAEPAIRNANMISFDISSIRSSDAVANGNAAPNGFYGEEACQLCRYAGYSDKLSSIGFYEFNPAYDQNGQSAMLMAQMIWCFLDGFYNRKKDFPMNPKSDYIVYKTSLQEDGHELIFVKSKKTDRWWMQVPYPSAGSKNERFHFVPCLYEDYQLAVSGEMPDLWWRTYQKLN
>NZ_CP043329|3386789:3444875|3442419_3442635_-|WP_149075548.1|DBSCAN-SWA
MKTLKYTALTGFLVGLTFFLIGFFYKFNHIPGAKLWVHIGAFAYILMLLSIVALFIYFVMNYLKLKKQLRA
>NZ_CP043329|3386789:3444875|3395902_3396103_+|WP_149075512.1|DBSCAN-SWA
MKDIIYTHSLLVVDSKGQIFRIFTPFLVIEKLTQQKYWVSKIVWDAFGLPYFEIEGNLAIYSKFKI
>NZ_CP043329|3386789:3444875|3416932_3417781_+|WP_149075531.1|DBSCAN-SWA
MKSTLLHLRLPFSLLLLPVYLFAYSEVPNPNIYNAIVVFIVWHLFVYPASNAYNSYFDKDEGSIALIKEPPKVQKSLLVTAYVLEWTGLLMAFLVSFEFALAVAIYNSFSKAYSHPRIRIKKYPILSFLVVFIFQGFFIYYSCYQAIGQYDLGLNADVIQAGLISSCLIGASYPLTQVYQHEEDNRRGDKTLSLLLGVKGSFLFSGFVFFLGFALMFDYWNRQNELHNFWVFALCCSPILGYFLWWFKQCLNRVEAASFKNAMGMTLISGLMMLLYFGWLWL
>NZ_CP043329|3386789:3444875|3432909_3433194_-|WP_149075542.1|protease|DBSCAN-SWA
MAGTQTQEETFTLDEILSSLKTVHRLILWNDEVNTFDHVIYCLMKYLDYSENQADKIAWTVHNEGKCAILEGSLTEMEVYRKILKQEGLTVSVD
>NZ_CP043329|3386789:3444875|3441130_3442423_+|WP_149075547.1|DBSCAN-SWA
MNQYFIIDFDSTFTQVEALDELARISLKNHPDREAIYKKIEDLTNLAMEGKLSFSESLEGRVKLLEANKDDLKKLIKHLKTKVSSSFSRNKVFFKKHAKEVLIVSGGFKEFITPVVTPYHIKKENIYANTFIFDEQGKIIGYDKANPLSEEGGKVKLLQRMSLKGDIYGIGDGHSDFQLKESGLIKKFFAYTENIERKAVAEKADHVTPSFDEFLYVSDLPRAISYPKNRILCLVVGNVPEESIQLLKKDGFSIRHKETFEDKYVQDVGMLLLADGEKVDKATLKKAVKLKTIGYFGNAKGNIDFDVCTEMGIVVFDSVKSNLTHKTLIARRMADFINTGTTYMSSNFPNLQLPKIAGSHRLIHIHENVPGVMAKITKVLAKHQINIVGQFLMTNPLIGYVITDTDTEYDKALLKEMRKVENTIKFRVLY
>NZ_CP043329|3386789:3444875|3422626_3425080_+|WP_149075538.1|DBSCAN-SWA
MKILKFGGTSVGSVDALKALIDVVKTNLDKQEQMVIVVSAMGGVTNQLITTAENAIKGIDFSEALADIEKRHFEVVKALIPVQQQNQVLTKLKLFFQELEDLMQGVTALQELSPKTRDAILSYGEQCSAFMISRILKTIHEGADYLNTTEIIKTDSTFGNARVDFEQSNFLIKNYFEHHKDSLIVATGFIASDDQNRVTTLGRGGSDYTSAIIGAALNVSQIEIWTDVNGMMTADPRRVKKAFSLEELSYTEAMELSFFGAKVIYPPTMIPAFLKKIPIVIKNTFDASFPGTFIKHDIKPSSTVIRGISSVDHISIINLQGSGMVGKAGFSGRLFSLLSREQVNVVLITQSSSEHSITFAVNPEDAKKAQALIQQEFELELQAGKLEPITIEHDLSILAIVGENMKKTPGIAGKLFHALGRNGVNVVAIAQGSSEYNISVIIYNSDLTKALNTVHDAFFAQLQKNLNVFIVGVGNISKELLSQINAHHAYLVENNLINIKIIGLTNTKKMLIEPAGIDLANWQQSLDESTEPADLNKFVSEMKSLNLPNCVFVDNTASPIPSTLYKDIFKSNISVVTCNKIANSGDYKQFADLRSTAQKYGVDFLYETNVGAGLPIITTLHDLIISGDKITKIEAILSGTISFIFNNFKGDVTFHDVVKQAQEKGYTEPDPRDDLGGIDFMRKILILARNSGLAMEAADVDLGAILPENCAKAPTVEAFYQELKVSNDYFEQLKKDAEKQGKVLRYIGKLENGKASISLQAVGMDHPFYALSGSDNIIAFTTERYCETQMVVKGPGAGAAVTAAGVFADLVKVGANQ
>NZ_CP043329|3386789:3444875|3420011_3420761_-|WP_149075535.1|DBSCAN-SWA
MITTEEEKKEAQEFYKEALQLLKECGVDFMLGGAFSLFAHTDIYRDTKDLDIFCKPSDYSKILQFFADKGYKTQLTDIRWLAKVFKGDYFIDIIFDTVNNICTVDDSWFEHATPGTFAGEEVKFLSPEELIWCKIYVQNRERFDGADINHVILKKGKELDWERLLSRLDQHNHWHLLLAQIIMFQFVYPSDFHEIIPQWLFDELIKRANNQYQLPATVVKVCRGPVIDQTQYSVDIKDWNYKVSTIMTT
>NZ_CP043329|3386789:3444875|3419252_3419999_-|WP_149075534.1|DBSCAN-SWA
MTDTTKNTRIAAVADIHVKESDKGKWTAYFKEISEKADVLVICGDLTDTGDESEAAVLAEELKACSIPVVMVLGNHDYEKGREKMIRQLLLKDHVHVLDGEAIVIHNIGFAGIKGFGGGFDKHMLSMFGEKGMKDFVQEAVNEALQLERALARLESDHQDIKKVALLHYSPIVETVKGEAEAIFPFLGSSRLAEPLSRRNVDVAFHGHAHIGTLKGKTQDGIEVFNVAKPLLLRDGYDCPYFLYEITA
>NZ_CP043329|3386789:3444875|3397447_3397843_+|WP_149075514.1|DBSCAN-SWA
MINSLVINLIILAICLIINIAYLNSKVNRIPNHYIFKLIGNINTIGILIIIILIGIKVSVWYAILTFVIALIISRIAHVIFNDSLTNLKRQINAVDPNSSEKYSFMSIAIIPINLFATYIIIQALINLFRM
>NZ_CP043329|3386789:3444875|3433273_3433783_-|WP_149075543.1|DBSCAN-SWA
MVLHLPLRKGLFLCNLKGNDELKLSFLLFYSFRTLLLENLGFEIIDDKKSKLIDAIKTQIIELIHHQKEALHINLSDFLSRQLKHDYSYLSNLFSEKEGITIEKYFITQKIEKVKELLIYDELSLSEIAYQLNYSSVAHLSSQFKKVTGLTPSFFKNLKGNKRIEIEKL
>NZ_CP043329|3386789:3444875|3434988_3435180_-|WP_149075544.1|DBSCAN-SWA
MVIYIKNMVCSRCKMVVEQVFQELNLQPEQVLLGEVHLKEAPTEKQVNTLKLELENQYCPKRL
>NZ_CP043329|3386789:3444875|3437649_3438765_-|WP_039454735.1|DBSCAN-SWA
MKKILLGLLLQVPVLAFAQFSLKGEFSAASQNKKLYFIHIQNNAEVIDSAVVNNGKFSFNLDLKEPSVAVLLLQHEGNALKDKGPKDVYRFFIEPGNATLTAKDSIAQAKVNGLTIFKEDVAYKTATQASESKLIALNKEFAALAPEKKAKQETIESFQGRYLNLLEERKAQIINFIKANPQSYISLYAFNQDLGIDDMEYSQAESLFSGLQDKVKKYALAAVIKQKLDIAKVTGIGAMATDFEEKTPEGIPLKLSSYKGQYVLLDFWASWCGPCRKENPFVVSAYEKYKDKGFTILGVSIDTDRNAWQKAIKTDNLMWAQLIDSTTEISKIYGIDAIPKNFLIDPSGKIVAKNLRGGALEDKLKEIFDKK
>NZ_CP043329|3386789:3444875|3421417_3422338_-|WP_149075537.1|DBSCAN-SWA
MQGLVIKSTGSWYTVLGENQHKYECRIKGKLRMKGLVSTNPVAVGDFVDFELEPEQETAVINRIHDRKNYIIRKSINLSKQVQVIAANLDQACLVVTLASPRTSLGFIDRFLVTAEAYGIPAILIFNKLDLFSDEGLEILANYMDLYEGIGYKCYAVSAIEGTHVNTIKELLKDKTSLFSGHSGVGKSSLINQIIPGIALRTGEISDWSDMGKHTTTFAEMFELPFGGKLIDTPGIRELGIADIEPEELAHFFPEMRSRMHGCKFHNCVHINEPGCAILKALDEGNIEPTRYDSYLSIYHKNDTRA
>NZ_CP043329|3386789:3444875|3388000_3388402_+|WP_149075506.1|DBSCAN-SWA
MISKIKHLLIFFLAVFISSCNQKSKSEEIEELVIFGNSGFCLKDNNGNSYSSTYWIDCDSCDTKDLKYDSTKLDIRLYFEYKKDDHTKTSIRKPESTTEYYILSEQETQGFKSLINSTLLSNNLSSINQKAKI
>NZ_CP043329|3386789:3444875|3402960_3403191_+|WP_149075520.1|DBSCAN-SWA
MDLQTRKLNIIQYLIELKDEKLFNKIETIIKDKIGNEKLKPFTQEELLSRIKHSNDDYLTGNFKTQEQLEIESENW
>NZ_CP043329|3386789:3444875|3389851_3391381_-|WP_149075507.1|DBSCAN-SWA
MEEIIVDNSSVLELFNIHLKLKDNKRVLFTAPFGSGKSYFLNEFFENSQEYLKITLFPVDYSVASNEDIFELIKFDIFDYLIDHYFEELDLKKDDFSNLLLAQSFVSSKLNLFPFLSSLSKFFPKIEGLVDIIKDTKELINDFKRFKKDVEEGEVEQLLKFMTSIEYKKGSYKERDEFTVLIQDFLKRIKVKRENKEFVLVIDDLDRLDPDHTFRLFNIFTAHHDSKSDTNKFGFDKVIFVCDIPNIEHMFHHKFGAKSNFEGYIDKFYSYKPYFFNHKQYLKEKISDYLDSSFIENSNTKHRKINKDSNFFSDILRLTYKFIDKDILRIRNLKKLTDFSIPDCEIKVKGRSYHVSNFPLLIMTNIMCQFFPRIEDFVRIIGDLSDNYSSNYGTSREVIWNHDYFLISYSIPFFIEIRDIRKNIKITEDLIIGVDNEFGERIFLVYDVKEDWETDSLSFYFKKAVNNTGIIIGKISESEVYINPNPFHVFKKALEICIDNGYIYNDNKY
>NZ_CP043329|3386789:3444875|3403733_3406766_+|WP_149075522.1|DBSCAN-SWA
MKKILLLIGALFCVAMVQAQETFPVNGSYDIRSGQFAFTNANIVVSAEQTLKNGTLIIKDRKIEQVGTALNIPKGYVIIDLKGKYIYPSLIDAYTSYGLPEIPRQSFSGRGSAPVFTTTKQGAYHWNEAIKPEMNAHSIFNLEAKKAEEMKKNGFGTINTLIKDGIARGTSAAVTLGDESNNLVMLSAKTAANYSFSKGTAKTDYPSSLMGSIALLRQTYIDAAWYKSQSKEFNISLDEFNKQQSLPQVFEVENWEDVLRADKLGDEFGKQYVFKSGGDEYQRIADIKATTGKFIIPINFPKAYDVEDPADARSVTFAQMKHWELAPTNPAVLEQNGITFAISPAGLESPKDFWTNLRLAIDFGLSEKQALKSLTEIPASILGIDKKVGTLNVGKEANFLITSSPLFAKENIIFENWVQGKRFIVSQMDVKDLRGDYDLVIAGLGKLDMKIGGSIGAYEVNIVRTGADSVKTKANFVRNGDLVNLVFDLTKNPKGDFRLSGYLDKASPLTFKGEAVAANGNTTNWSATFKAPFIEKEKKEEAKGVSQVGKVVYPLVAYGNPDLPKTEAIIFKNATVWTNEKDGILKDADVWVENGKIKAVGKNLSTNNAKIIDAKGKHITPGIIDEHSHIAISRGVNEGTQAVTSEVRIGDVLDAEDVNIYRQLAGGVTTSHLLHGSANPVGGQTQLIKLRWGNTPEGLKFGNNPGFIKFALGENVKQSNWGEFNTIRFPQTRMGVEQVFIDAFTRAKEYKAAMAAYNGAKNKSGLTQPRKDLELEALVEILDGKRHITCHSYVQSEINMLMKVADSMDFKVNTFTHILEGYKVADKMAKRGIAGSTFSDWWTYKMEVLDAIPYNGKLMHEAGVLTAFNSDDAEMARRLNQEAAKAVKYGGVSEEEALKFVTLNPAIMMHIDDRVGSLKPGKDADLVLWSEHPLSVYAKAEKTLVDGIVYWDYEKDEQKRKEIKEEQARLIQKMINAKTKGAKTQRPSLEKPSLYDCDTLEGEHAETEEH
>NZ_CP043329|3386789:3444875|3393663_3394005_+|WP_149075509.1|DBSCAN-SWA
MVTVTNYLQKENAEGKAFFMLELTGELEIVVSQTTGKPYATVRKVSIPTTLDENMCKLMLGKQMPGQIAKVEVEEAYDYTNKETGEVLSLNYRYEYSATEKAQTMEQAVFQVS
>NZ_CP043329|3386789:3444875|3413972_3415100_-|WP_149075528.1|DBSCAN-SWA
MSKKPKIFIAGGGLAGLTNAILLSKAGFEVCLAERKFYPFHRVCGEYVSNEALPFLKSLGLNPEDLQASKLEKLIIAAPSGKTILAPLDLGGFGISRYTLDEQLYLIAKQQGVEFLLGEKITDIQYHDEQFNILLAGKTYQADLVIGAFGKRSNLDKQLQRSSFYKRSPYMGVKYHVKLDFPKDTIRLDNFEGGYCGLNSIGTDSYCLCYLSENKHLKKYGSIAAVEEQVLSKNPFLKEVFRHAEFIWDKPETINEIAFERKTLIENHILMCGDTAGMIAPLCGNGMAIAIHSAKILSSCIIDICPDGINPTKRAQLEKAYSQTWQQEFAQRLFIGRTIQKLFGQNVLSEMAIGGLNHFPKVFSFLISKTHGERF
>NZ_CP043329|3386789:3444875|3418241_3418889_-|WP_149075533.1|DBSCAN-SWA
MQELIYKTIAFVKQELQNAEAGHDWFHIERVWKTAKYIAAEEKVNLLVVEFAALLHDIADAKFHDGDEEIGPRKAGDFLKTLAVDDETIIHVQQIIKNMSFKASLGDVTFTSAEMLVVQDADRLDAIGAIGIARAFTYGGYKNRELYNPEIKPEPNQSKEAYKKSTAPTINHFYEKLLLLKDKMNTATGKKLAAQRHDFMVQYLTQFYAEWNGEK
>NZ_CP043329|3386789:3444875|3440091_3441066_+|WP_149075546.1|DBSCAN-SWA
MILITGATGFLGAQLTKQLLAKSIKVRCIKRASSVIPEVLKPYESQIEWFDADILDVSDLIDAFEGITHVYHCAAYVSLNNYNEKEMMAINVDGTANVVNLCLSFGITKLVYVSSIAALGQVKPGETITENNYWDAYDKNGAYAISKYRAEMEVWRGVEEGLKAVIVNPSVIIGAGIGKQGSGKIFETVKKGLNYYTSGGTGLVDVEDVACLMIKLMEHEVINERFIINAENYSFKRLFTEIAVALNLKAPEKELKEWQARLFWRLASFLRLLKIKIPVVSKDLLKAAFQTQEYSNHKVSSLLSYHFTPVNMSITKSVNGIKSF
>NZ_CP043329|3386789:3444875|3398471_3398720_+|WP_149075516.1|DBSCAN-SWA
MKPVQIFKYCEQEDYKLPDTADIDVIPLECINCILDDILSTSENIRKDWIKLYKDGNMQLQCRLTGKKHLITKEFFDKVKWD
>NZ_CP043329|3386789:3444875|3425079_3426012_+|WP_149075539.1|DBSCAN-SWA
MSSKSIKVYAPATVANVVCGFDILGFAVNEPGDELIMDLCDKPGVVISSIEGDGGKLPLDADRNTVAAGVKSILKQLGREDIGVKLKLKKKMPLGSGLGSSAASSVAGIFAINELLDRPLSKEELLPFAMEGEALACGHGHADNVAPALFGGFTLIKSYEPLEVIALPVPNLYCALLYPHVDVPTRDARQIIRSKVLLKDAVTQWGNIAGLISALYLGDYDLLGRCMKDVIVEPIRSMLIPEFYKMKEIAMHHGALGFGISGSGPTVFSLFRSPDDAQRVLLTLQQVLLDKGIASNIYLSEINKNGPVIL
>NZ_CP043329|3386789:3444875|3443483_3444875_+|WP_149075550.1|transposase|DBSCAN-SWA
MERSTYSGYFGDKRLEHRGYMLRQRLFSSCTQSIQALSLNRAEQKAYYRFLHNSRTAESKLIAELMKRCSIQSKGRVVLSIQDTTEVNLSRHKGRLQACSGLGGIDDSKGIGFKLHPSLVVDAETCFPLGFSSIRMWGREQDKGNKTERRYMNLPIEEKESYKWIEASKQSQETLHQAKAVVIVQDREGDIFEQFLRIPDENTHLLIRSCFNRQTNDEEGKLWDQLSASEKLGEYQIKVDSDSHGGTPARQASLEVRSIKTNIRPPKEGKGKCVQVYAVEAMEASTENYQGIHWRLLTTWPVEDFDQARLIIEWYSWRWVIEELFRMLKKEGFNIEGSELETGWSIRKLTVMLLDTIMKLMQMHIAYSEPEEANIPDTDLVFSEDEQECLLALNKANEGKTQALKNPFQAGKLNHAVWIISRIGGWKGYRSQRKPGMTTMFKGLNKFYNIYDGWILQKDVGTR
>NZ_CP043329|3386789:3444875|3411505_3412489_-|WP_149075527.1|DBSCAN-SWA
MKIAVFSTYHYDEEFLNRYNTGHELTFFTLALHADTAPLANGFDAICIFVNDKVDKAVLEILKAAGIKLIVLRCAGFNNVAVADAKAMGITVVRVPAYSPEAVAEHAMALILTLNRKTHKAYNRIREGNFSLERLMGFNLHNRKVAVIGTGNIGKAFCKILSGFGCKISAYDLYPQDEVKAMGVQYGTLEETLCDADIVSLHCPLTPETQYLINQKTLKLFKHGAMLINTSRGALVHTKDAIKALKSGQLGALGLDVYEQEGDLFFHDLSEGIIQDELITRLISFPNVLITSHQGFFTQEAIGEIARVSFANIDAFCNGEELKNKVD
>NZ_CP043329|3386789:3444875|3398170_3398494_+|WP_149075515.1|DBSCAN-SWA
MINIKPYTTIKTILIALLLLCLLNLPYGLYQLFRVIFTIGFVLLAIKANEDKKQTELTIFIVLAVLFQPLLKIPLGREIWNILDVVVALGLIVNLFKTSKNETSSNI
>NZ_CP043329|3386789:3444875|3418888_3419215_-|WP_026905198.1|DBSCAN-SWA
MEIKEAQQLVDNWIKTTGVRYFNELTNTAILMEEVGEVARIMSRKYGEQSFKESDKKVDLGDEMADVLFVLICLANQTGIDLTAALEKNLEKKSIRDADRHRNNEKLK
>NZ_CP043329|3386789:3444875|3406778_3408080_+|WP_149075523.1|DBSCAN-SWA
MKKIIYQFIILTVAACTAYAQPNIAPAKAQTQAIALVGATLHIGNGTVIENGIIVFDKGKITAVGDGKTALPQNANVIQVSGKHIYPGFIAPANGLGLTEVESVRATRDIQEVGFINPHVRSIIAYNTDSRIIPTVRSNGVLLSQPAPEGGLVSGTSSIVQLDAWNWEDAAYKTDMAIHFNWPTSRIRTSRRAGAAVSEEQQKERYQRQMAELQNYFEEAKAYAELSKPKVFNARFDAMKGLFTGTKKAFVNVSAQKDIIIAVKFFEGFGIKPVLLGADEAIQVAGFLKEHQIPVIVNESHALPANDDDDVYLPYKNAALLHKAGILIAMSIEGYWQQRNLPFMAGTAAAYGLSKEEALALITSNTAKILGIDKQTGTLEIGKDANIIISEGDALDMRTNNISKAYIQGRDINLDNVQKQLYKRYAEKLGIKE
>NZ_CP043329|3386789:3444875|3442673_3443354_+|WP_149075549.1|DBSCAN-SWA
MSNSQTLPILNAEEIRVLGALMEKSKTTPDYYPMTLNALTAACNQKTSRKPVVAYDEETVVMTLDSLKKKGLISTATGGGSRTVKYKHNFAIVFPVVPQEVALICLLFLRGPQTPGELNTNSGRLYEFESIEDVQQTLEKLATEEPAYVVQLPKRAGQKEARYAHLFADVVLDEDDDLPEEPARKSVGELEARLAKVEDELAELKAAFDKLMKELMDSYSVVSSYK
>NZ_CP043329|3386789:3444875|3436732_3437608_+|WP_149075545.1|DBSCAN-SWA
MIKGFKIVFTFLLILSIAGCTSKRYEWVKVNPEKLHLAKTAKPYSESVRRVNIYINAKHKAELLVYEDADTFLQKNIVPSAQPISKVNRPIKQNKIAKLSTTKKIVAKKSPAIALVKPAPAVKANKQVKLTKPAVKEKTDEEEALSKLNSALILPKKKPKQTIQPKETAVESVTQKEQARQQAGVSPMFSDQADSKTQEATQKSPKAVEDQEVTSSPAEEKLEETQADNLNNPEEEVKNSEEGAFKRNNYMWVGLVLIIIGLIIGLVFGGMAYFISVVGVIFLLIGYFYKV
>NZ_CP043329|3386789:3444875|3386789_3387980_+|WP_149075505.1|integrase|DBSCAN-SWA
MNTHIYSLNPTCTQPRGVGKSVKDKWYVYFYYTNSNGIRKSFKSYKDLNNKNQDLNQRRKLLAETVAKFDELLKTKKFDIETGIFIKTVSEQVLINNLIEDYLKFKKAIISHYTYLNYNSLFERFKLSAKGLTLSQIDQQFIKDFLKKTPAKPQSKRSYRTYVSGFFNWLKDEKDINIINPTHGLRLDRNEPVERHKIYSKEEIKAIIDYCDANGHVILKTIIYLVYGAQMRISEILRIQVEDINLDYNKIVLPKGKGKIKNREKIVLLDEPLKVYLLNMGLDFKDKDNQKLYFIGQKRAYDKAKFFGRYPISKNTIDTRFKLLKKDLNISLHKTLYSFKHTGNVNLLLSGADLIELMYKNGHKKISQTETYARQLIEQVPETKYIRKSRDDLDFK
>NZ_CP043329|3386789:3444875|3427772_3430226_-|WP_168199460.1|DBSCAN-SWA
MLQPIRFWLILSIITISLQVFSQNLPVNAPGIIKGRVLDIKTNLPIPFAALSLTDSVSTPKSLQNDLEGNFTINNLKPGSYTLKISYVGYQNKAITQIAITDTRFEIDLGDILLNANDKLLNEVVVTYQKPVVEMHDDKLVYNISETIAGEGSVAADVLKNVPMVSVDIDGKATIAGRRNTRIFIDGKPSDYSANSIGELLSILPSDALESIEVITDPSSKFDADGDGIINIVMKKGRKVGLTGTLSSRFGTLGNHNAGAFLSSKGKKLSFNANAGYSHALRLSDANSNRTNNVFDTNGAIDTTFFNDQTNNAERITDGVDSRVSITYQPDSAQVLKATLRGSYNDGFSESFSDNLSLTEERIERNLLRQNNTNGNNSYDFVMDADYTLRGKNKQNYTVGINYNRNNYTDLRDFSRFSYRPDGTLRNPEPTLQQNSNNNVGSNLELNLDYDKTFKFLNTRLETGFKINLNNSDENQLAQRFDYDVNEYVVNDALTNAFLFKQNVYASYLTARFRIKKWSIRAGTRAELTNINFIQENMPNADFKPYMSFFPSLAVTRSFSKTMRGGLNYSRRITRPRAFALNPLIDNSDSLNIRFGNINLRPSFTDQYEANITFFGKGWSVSPRISYAISSRIIERIKTPIAGTNGTETTYLNLGNSSSINFNTFANYQIDKTKNMNAGFTVSRVSYESAANSRLNNTGIAVRANAGMSYSFDKSTAMEANLNYIRNVSAQGIVNGYLESQFGFKRNFLKNRMSARVTMVDPFSERNFSSITQGQTFFQESFSLQRTRNFMAALSYRFTKINGGNTKAVIPKKRVNP
>NZ_CP043329|3386789:3444875|3388383_3389277_-|WP_149074804.1|transposase|DBSCAN-SWA
MIDYSKISDIFCLVDEFCKDFDNNTHSFLLGKASKRPPVMSKSEVISICLFFHLSGFRCFKHFYLFYIQRHMQSEFPKTVSYNRFVELSQSILMPMTIFLKTCCLGICSGISFVDSTPVRVCNNKRIKRNKVFKGIAEVGKSTMGWFYGFKLHIVINDKGEILNFAITQANVDDRDPLKNENFLKSVFGKLFADKGYISEKLANILFVNDIHLITSIRNNMKNSLMTMNDKITLRKRSVIETVNDELKNICQIEHSRHRSFTNFISNMIAALIAYSFFPKKPSIKYQNANSNQILAF
>NZ_CP043329|3386789:3444875|3417785_3418238_-|WP_149075532.1|DBSCAN-SWA
MENTFLYFAYGSNLNKALMEFRVNDPVTVVGSAVLYGYGLCFHQLNADGSARANLVVSESENVHGVLYQVHAKHFELLQQTEPQYQLQEFELESDTGIHQAYAFICVDEAEELSPEEEYLNTLLEGATQHQLPENYISYIKHKANFKAED
>NZ_CP043329|3386789:3444875|3398977_3399340_+|WP_039455242.1|transposase|DBSCAN-SWA
MDSTLLSLILPEGLSEYFELDKVETVSDSYYIYLKERNIQPKEFTAQKLISKGFFEEISVRDFPLRGKPCFLKLKRRKWMIVETGEIVFRDWNLVAEGTKMTQEFAFFFERLFGFKPNKL
>NZ_CP043329|3386789:3444875|3408253_3410221_+|WP_149075524.1|DBSCAN-SWA
MILRGPKIKQLLRSIALLVFLLLPIFGAAFQKAYRLNPQLKVYDSLVSRYRYFKPDSALYFMNQGLELATKLNDANGKAVMLNQWGMIYDNKGNYQESREKYLQALKIYQKTGYVKGISAVNIRLGVVENRKGNHDKAIAYFLKALAISEKNNYAYGIMEANLTVAEGFLGQKNYPIALKYLKKAEFISDTIPFSNLNLNIYNNFGVIYRDIKKYDLAEYYLKKGIALSSNIKYQGLNITLTNNLASVYARTGKKQQAIALQKEALKKAKEIQNFLREIEVLLGLAENYKDTDSKKALAYYKDALNLTRKNNAYKRQVEILNQMVILYRKEGNYKEALTLKEEEKNLADSFLYKDIDSRISDLQAQYELAKSQARVKELQYSNTQQNLRSTIILSVAVFVMIILVFMVFNNRRNRKFNQLLSKANQELKESNSVKDKLFSVLAHDLRGPFAAIINLLSMVKDGYLDEREKNELIDKITQNSTTYLDTLNDLVKWGETQIKGLRINPQPIALAQEVELNKEFLSVLIEDKNISFSNEILPHVAVLADKAHFDLIIRNLLSNAVKFTNTGGSIKVFAEDESQYIRITVKDTGIGMSADKQSRIFNFENISLAGTGNEKGNSLGLILCKEYVLANKGTISVKSKKGEGSEFSFTLPKA
>NZ_CP043329|3386789:3444875|3396506_3397271_+|WP_149075513.1|DBSCAN-SWA
MKKVLLLMLTASALLGACKKDKDDSNPANGCKIVKFTPSGGHDYVNSEYLITYNSDGKISTITNADETRRFSYESSKMLVSVDNLLITYNYNSPNQINSIITNSQWPENVSVTYADNKVSKILTSVDDISSTFTYSSNEVVKILEKWGDTDTEEALITYKEEKYSNPLIFELIFPSMIDGDIRNFIRYNLSNSFGASEKRLIDKIEYIGKGDRSYNTRTDTYSYLKDDKGNIIQIIITSTSYTTRSFTLEYSCN
>NZ_CP043329|3386789:3444875|3415781_3416885_-|WP_149075530.1|DBSCAN-SWA
MSSVISAIGTSNPSNQFAQSRILEFMKEAHQLDSNQARRLEKLYQVSGIDYRHSVLQDFGKQKGNYSFFGNDDGLNPFPTTASRGFIYEQNALQIALKAVENCLKQLDFNPQNITHLITVSCTGMYAPGLDIELVEKLGLKPDTERTCINFMGCYGAFNALKVADYICRAQPTAKVLIVDVELCTLHFQKENTLDNWLANSLFADGAAAVLVQHEAQTDDKLFHINSFYSELISKARNEMAWRIGDFGYEMQLTSQVAKQIRSGIKDIAQKLLKKAQLAFDDIGQYAIHPGGRRILEVCDDAFQLHSHQNEHAYEVLRNFGNMSSATVLFVLAALSKKLKTKQQEEKILSFAFGPGLTFESMVLTYA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3386552:3386611	attL	NA	NA	NA	NA
WP_149075505.1|3386789_3387980_+|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149075506.1|3388000_3388402_+	hypothetical protein	NA	NA	NA	NA
WP_149074804.1|3388383_3389277_-|transposase	IS982 family transposase	NA	NA	NA	NA
WP_149075507.1|3389851_3391381_-	hypothetical protein	NA	NA	NA	NA
WP_149075508.1|3391493_3393455_+	hypothetical protein	NA	NA	NA	NA
WP_149075509.1|3393663_3394005_+	hypothetical protein	NA	NA	NA	NA
WP_149075510.1|3394091_3394925_+	AAA family ATPase	Q94MN8	Myxococcus_phage	1.2e-33	37.4
WP_149075511.1|3394927_3395890_+	DUF3871 family protein	NA	NA	NA	NA
WP_149075512.1|3395902_3396103_+	hypothetical protein	NA	NA	NA	NA
WP_149075513.1|3396506_3397271_+	hypothetical protein	NA	NA	NA	NA
WP_149075514.1|3397447_3397843_+	hypothetical protein	NA	NA	NA	NA
WP_149075515.1|3398170_3398494_+	hypothetical protein	NA	NA	NA	NA
WP_149075516.1|3398471_3398720_+	hypothetical protein	NA	NA	NA	NA
WP_039455242.1|3398977_3399340_+|transposase	transposase	NA	NA	NA	NA
3398809:3398879	attR	NA	NA	NA	NA
WP_149075517.1|3400446_3400626_+	hypothetical protein	NA	NA	NA	NA
WP_149075518.1|3401009_3402386_+	hypothetical protein	NA	NA	NA	NA
WP_149075519.1|3402388_3402577_+	T9SS type A sorting domain-containing protein	NA	NA	NA	NA
WP_149075520.1|3402960_3403191_+	hypothetical protein	NA	NA	NA	NA
WP_149075521.1|3403195_3403369_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_149075522.1|3403733_3406766_+	amidohydrolase family protein	NA	NA	NA	NA
WP_149075523.1|3406778_3408080_+	amidohydrolase family protein	NA	NA	NA	NA
WP_149075524.1|3408253_3410221_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_149075525.1|3410247_3411135_+	DUF72 domain-containing protein	NA	NA	NA	NA
WP_149075526.1|3411146_3411509_+	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_149075527.1|3411505_3412489_-	2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	7.8e-64	40.9
WP_149075528.1|3413972_3415100_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_149075529.1|3415096_3415789_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_149075530.1|3415781_3416885_-	type III polyketide synthase	NA	NA	NA	NA
WP_149075531.1|3416932_3417781_+	UbiA family prenyltransferase	NA	NA	NA	NA
WP_149075532.1|3417785_3418238_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_149075533.1|3418241_3418889_-	HD domain-containing protein	S4W232	Pandoravirus	1.2e-15	30.7
WP_026905198.1|3418888_3419215_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_149075534.1|3419252_3419999_-	metallophosphoesterase	NA	NA	NA	NA
WP_149075535.1|3420011_3420761_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_149075536.1|3420834_3421293_-|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_149075537.1|3421417_3422338_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_149075538.1|3422626_3425080_+	bifunctional aspartate kinase/homoserine dehydrogenase I	NA	NA	NA	NA
WP_149075539.1|3425079_3426012_+	homoserine kinase	NA	NA	NA	NA
WP_149075540.1|3426085_3427390_+	threonine synthase	NA	NA	NA	NA
WP_168199460.1|3427772_3430226_-	TonB-dependent receptor	NA	NA	NA	NA
WP_149075939.1|3430284_3432777_-	TonB-dependent receptor	NA	NA	NA	NA
WP_149075542.1|3432909_3433194_-|protease	ATP-dependent Clp protease adaptor ClpS	NA	NA	NA	NA
WP_149075543.1|3433273_3433783_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149074277.1|3433764_3434937_+|transposase	IS4 family transposase	NA	NA	NA	NA
WP_149075544.1|3434988_3435180_-	hypothetical protein	NA	NA	NA	NA
WP_039454718.1|3435272_3436547_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_149075545.1|3436732_3437608_+	hypothetical protein	NA	NA	NA	NA
WP_039454735.1|3437649_3438765_-	AhpC/TSA family protein	NA	NA	NA	NA
WP_039454722.1|3438770_3439955_-	formimidoylglutamase	NA	NA	NA	NA
WP_149075546.1|3440091_3441066_+	NAD-dependent epimerase/dehydratase family protein	A0A1B1MRD1	Pteropox_virus	1.3e-07	26.8
WP_149075547.1|3441130_3442423_+	HAD-IB family phosphatase	NA	NA	NA	NA
WP_149075548.1|3442419_3442635_-	hypothetical protein	NA	NA	NA	NA
WP_149075549.1|3442673_3443354_+	DUF480 domain-containing protein	NA	NA	NA	NA
WP_149075550.1|3443483_3444875_+|transposase	IS4 family transposase	NA	NA	NA	NA