CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042425	Gemmataceae bacterium PX52 chromosome, complete genome	17 crisprs	DEDDh,csa3,DinG,RT,cas4,cas3	1	4	23	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042425_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_1

748345-748440

Orphan

Consensus_repeat	Method
CACCGATTTTAACGCCTCGACGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_1

>merge|NZ_CP042425|1|748345-748440|CRISPRCasFinder
CACCGATTTTAACGCCTCGACGGCCCCATACCACTCTTGGACAGCCGCAGAAACGGTGCCTGAAACCCGTCGGCACCGATTTTAACGTCTCGACGG

>NZ_CP042425|1|1|748345-748440|CRISPRCasFinder
CACCGATTTTAACGCCTCGACGG	CCCCATACCACTCTTGGACAGCCGCAGAAACGGTGCCTGAAACCCGTCGG
CACCGATTTTAACGTCTCGACGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149108688.1\|759179_759608_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|284381
NZ_CP042425.1\|WP_149108675.1\|741860_743708_-\|TIGR03960-family-B12-binding-radical-SAM-protein	unknown	unknown	gnl\|CDD\|188475
NZ_CP042425.1\|WP_149108679.1\|746691_747621_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234605
NZ_CP042425.1\|WP_149108678.1\|745156_746695_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149108676.1\|743801_744227_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168218779.1\|755310_756342_-\|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|179673
NZ_CP042425.1\|WP_149108680.1\|747760_748165_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP042425.1\|WP_168218780.1\|759663_760167_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379753
NZ_CP042425.1\|WP_149108682.1\|749808_751716_+\|HTTM-domain-containing-protein	unknown	unknown	gnl\|CDD\|214802
NZ_CP042425.1\|WP_149108674.1\|740505_741777_+\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP042425.1\|WP_149108690.1\|760227_761145_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226304
NZ_CP042425.1\|WP_149108671.1\|735919_736948_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168218778.1\|754145_755225_-\|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl\|CDD\|335469
NZ_CP042425.1\|WP_149108681.1\|748582_749812_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149108686.1\|756418_757822_+\|Si-specific-NAD(P)(+)-transhydrogenase	unknown	unknown	gnl\|CDD\|235373
NZ_CP042425.1\|WP_149108673.1\|737338_740509_+\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	unknown	unknown	gnl\|CDD\|224309
NZ_CP042425.1\|WP_149108683.1\|751858_754066_-\|DUF1553-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NZ_CP042425.1\|WP_149108672.1\|736949_737342_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149108677.1\|744395_745160_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP042425.1\|WP_149108687.1\|757871_758909_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|290220

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149108688.1\|759179_759608_+\|hypothetical-protein	gnl\|CDD\|284381	pfam06941, NT5C, 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C). This family consists of several 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C (NT5C) proteins. 5'(3')-Deoxyribonucleotidase is a ubiquitous enzyme in mammalian cells whose physiological function is not known.	0.004901
NZ_CP042425.1\|WP_149108679.1\|746691_747621_-\|hypothetical-protein	gnl\|CDD\|234605	PRK00059, prsA, peptidylprolyl isomerase; Provisional.	7.43633e-25
NZ_CP042425.1\|WP_168218779.1\|755310_756342_-\|pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|179673	PRK03910, PRK03910, D-cysteine desulfhydrase; Validated.	1.77217e-104
NZ_CP042425.1\|WP_149108680.1\|747760_748165_-\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.82168e-05
NZ_CP042425.1\|WP_168218780.1\|759663_760167_+\|hypothetical-protein	gnl\|CDD\|379753	pfam15891, Nuc_deoxyri_tr2, Nucleoside 2-deoxyribosyltransferase like.	3.18873e-10
NZ_CP042425.1\|WP_149108683.1\|751858_754066_-\|DUF1553-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	1.95928e-100
NZ_CP042425.1\|WP_149108674.1\|740505_741777_+\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	8.55341e-14
NZ_CP042425.1\|WP_149108690.1\|760227_761145_-\|hypothetical-protein	gnl\|CDD\|226304	COG3781, COG3781, Predicted membrane protein [Function unknown].	1.07673e-49
NZ_CP042425.1\|WP_149108682.1\|749808_751716_+\|HTTM-domain-containing-protein	gnl\|CDD\|214802	smart00752, HTTM, Horizontally Transferred TransMembrane Domain. Sequence analysis of vitamin K dependent gamma-carboxylases (VKGC) revealed the presence of a novel domain, HTTM (Horizontally Transferred TransMembrane) in its N-terminus. In contrast to most known domains, HTTM contains four transmembrane regions. Its occurrence in eukaryotes, bacteria and archaea is more likely caused by horizontal gene transfer than by early invention. The conservation of VKGC catalytic sites indicates an enzymatic function also for the other family members.	1.73519e-23
NZ_CP042425.1\|WP_168218778.1\|754145_755225_-\|formylglycine-generating-enzyme-family-protein	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.31871e-23
NZ_CP042425.1\|WP_149108673.1\|737338_740509_+\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	gnl\|CDD\|224309	COG1391, GlnE, Glutamine synthetase adenylyltransferase [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms].	1.98131e-98
NZ_CP042425.1\|WP_149108686.1\|756418_757822_+\|Si-specific-NAD(P)(+)-transhydrogenase	gnl\|CDD\|235373	PRK05249, PRK05249, Si-specific NAD(P)(+) transhydrogenase.	0
NZ_CP042425.1\|WP_149108675.1\|741860_743708_-\|TIGR03960-family-B12-binding-radical-SAM-protein	gnl\|CDD\|188475	TIGR03960, radical_SAM_domain_protein, radical SAM family uncharacterized protein. This model describes a radical SAM protein, or protein region, regularly found paired with or fused to a region described by TIGR03936. PSI-BLAST analysis of TIGR03936 suggests a relationship to the tRNA pseudouridine synthase TruA, suggesting that this system may act in RNA modification. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP042425.1\|WP_149108677.1\|744395_745160_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.26921e-83
NZ_CP042425.1\|WP_149108687.1\|757871_758909_-\|hypothetical-protein	gnl\|CDD\|290220	pfam13485, Peptidase_MA_2, Peptidase MA superfamily.	0.00242888

>NZ_CP042425.1|WP_149108680.1|747760_748165_-|hypothetical-protein
MYSMVMMMAVASSGDVASFGKKGDGCCGGTPHVGLFAKHSSGCCGGGGLFSGLRHKHNSGCCGGTVAPACDTCSVPAPAPACGGCDAPAPCGTPSSPCALPGAPIVTPAPTAEAPKAMPAPVEAPKKDAPKKES
>NZ_CP042425.1|WP_149108679.1|746691_747621_-|hypothetical-protein
MPRGIVASVTLLVFAPALLAQAKPATSVAATVNGEPIRLDEVDAMLKRHSPVDAPLTTAQAKQLRAEVLNDLIDLQLLTQFLKQHGPQVPPADLDKYMQGVAASLRKQKKTLADHLKETGQTEQQVRDGWTRVIQLQRLIDQKATEAELKKYFEANRVFFENATVRVSHIVLRLGPTAPAGEQAVAMEKLKQLRLDILAGKIDFASAAKKHSVCPTARTGGDLGYITRKDAIVDEPFAAAAFALKPNEISDVVACDDGLHLILVTARKAGTPVAFEKVVDQVRDVYADEIRQSLLAKLRKDAKIEVTLP
>NZ_CP042425.1|WP_149108678.1|745156_746695_-|hypothetical-protein
MTPTAGGRVRSAIAILSVMVLAGWPAAGTPFRGDQALFAIFARELAAGAVLYRDYWDVTNPGIYAFYTAAGACLGFTEDGIHLFEWLYWLAFVAAVSEIVRRAYGLTRWPLAPAVLVGIGYFWPACSDPSQLTKVEGLVAFPLVVAIWAASRRTPRAAGLAGVAGGVVLAFKLLFGVCLAVGWGYLLYVVVRERGWRAAAEWVAFLALGVAAVLGAVCGYFAAHDALTPMLRTLFVDSRGMRAAAEPAGFDRLAGTVRWGMELYSAVFAAVVLGSWCRLRQGRDPFVVALWLVIGASASVILVQTWSWWTYHVLLPGVPTCVLAAYTWPAIWQRVSPHLTRREGVVLLACVLLALAPTCGHGANAYLRLLRHGGGFSAAGRAAARFAAGQAYREARELAAWATRPDAPTGAILVIGDPLVYWEATRRPAVAISGWSVELYHQELRNRLIEQVRRAKPVAVFVAGSPHGYDRLVQNRYPELQQILDTEYAAVERHDRGTWYQLREPAPHRAFP
>NZ_CP042425.1|WP_149108677.1|744395_745160_-|SDR-family-oxidoreductase
MKLPLFDLTGKVALVTGGNKGLGLAMARGLAEAGADIVIAARTEEQLKSSLDKILLGIHRCGAYFVCDMADREQVKQMAADALAKMGKIDIVINNAGTNHPQPVDEISDDVWDRLIEVNLSSCMAITRALVPQMKERKWGRVIHISSIFGQVSKAGRNVYSATKSALMGFTRASALDLGPFGITVNCLAPGPFLTDLPMSVLSDGEKQAFADHTALGRWAQAQELVGPALMLASDAGSYVTGTTLFVDGGYTAK
>NZ_CP042425.1|WP_149108676.1|743801_744227_-|hypothetical-protein
MTATAPANVPKQSIHDHCRGEEAKFKWIESEKVGYDLGETAIQNWVRVHWTGYLRAKWLEHLQGKCFWIELDRGDFGLLEQQFQDQQDLIGPILDRLKCGQENLNIICWAKANSIPLEPVIGILEALDINSRRLVHRFDRL
>NZ_CP042425.1|WP_149108675.1|741860_743708_-|TIGR03960-family-B12-binding-radical-SAM-protein
MLNTTLKDEVVRHLPRVKTPAQYVGGEINSVVKDHRQVRGKLCLAFPDAYTIGMSHHGLQVLYTIMNNDPQWACERAFAPWLDFEGVLRNGGLPLYGLETFTPLHQFDVVGFSLQYEVCYTNLLNMLDLGGIPVWSNERLVSDPLVIAGGPGAQNPELLAPFVDLFIIGDGEQSLPHVMNKWVELKERAIRDGDNTYRRRLEMLAEVAACSPWAYAPVFYEFDYHADGTIAAVNRTRSDVPTEIASCTINCDFDAIPLPTKPVVSFVQTPHDRLAIEIMRGCPHQCRFCQSTVIKRPLRMRSVEMIVQSALETYRNTGTNEISLLSLSTSDYPHFEELVKRMHEVFTPLGVNVSLPSLRINHQLRSLPSLIQGVRKAGLTLAPEVARDDMREQIRKRIKNEDLYVGCREAFKNGWQKVKLYFLCGLPGEREVDLDGIVEMAETIGQISREVTGRYKDVTASVSNFVPKPHTPYQWNGMASREYFHWAGDYLHRKKRMKTVKVKQHDIETSLLEGILTRGDRRVSPGLYEAWKRGARMDGWRECFNAELWWKAFRDCNIDVPFYSHRQRPMGERLPWDHVNVKKGRAYLEKEQERSVIQLKVMADAVGGEPTGCGG
>NZ_CP042425.1|WP_149108674.1|740505_741777_+|TIGR02996-domain-containing-protein
MTDREAFITAIAADPDADAPRLVYADFLEEHGDAARAGFIRDQVRLAKLRPDSDEYRQLFRRTADTLRANLPAWIQSLCDRFGSPTNWKPIRQPGRGLHVEIVAGPVPRGFADVRDVLQAVSFDRGFIVSLSGLFLTKEDVMQLAETLCENPITRLSLGPVDPTVWNTAAVAPLNQIRSLILRKPLNADVTLRVFSEWPWPNFQRLSLVRSTAESIMALCQTPVAKRLVGMRMELNRQAIAALNRFPLDDRLQEFAVSRPEYALNHAERQQAVTQLQAVAFRPTLKRLDLTGCTIGDRGLATFARGDVWIRLKALVLDRNRFGDPGWRDFVRSRRTPELKLLSASRNFMTNDGAVRLAQSPLAATLEYVDLRGNRIDGKGALALARALGDSPLKKLLLAGNPIREKDAEMVRKILGERVDIGG
>NZ_CP042425.1|WP_149108673.1|737338_740509_+|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase
MTPNLPAVSLSSLGPERAAALSPLLARLLPLTADPAMAANNLERLLAQPAAEPFLPALLDPAGGGLEVVLQLLATSQLFADTLVQYPDALEIVLRPAGRNPSTAELVQQLQAMIEAATDNTNVLRAFRQFRQTQVLRIGINDVIRDRPLEEITRDLARVADASIQVALQSALRSVSRKFGTPMAGRSPARLAALAFGKLGGDELNYSSDLDLMFVYDEDGETAGQRTSTVPNGEYFARVITELLRLLSSHTDRGFAYRVDLRLRPEGKTGPLARSLASTRSYYDVMGRTWERQALIKVRPCGGDLDLGREFVAAVEPFVYRKYFSFSEINEVKALKRQMELRANRAGDDDRDVKTGRGGIRDIEYTVQFLQLLNGGDLRAVHQRNTLLALESLEIAGCLTGNENYILADAYRFLRKTEHRLQLLFDLQTHRLPAGEAELTKLALRMGYGQVRSEPEVRSEPEVRSEPEVRTAERGPRIENEVLDLRSELRATNPPLTAQRRSPLDETNDRPLLQTRTLLVEPLELFLADLHDKTGRDRVILDHLLHQTFANEQGEAEPESDLILDPDADDATVRAVLGRYPFRDVAEAYRNLSRLAHESVQFLSHRRCRHFLASIAPQLLRAVAETPDPDAALNSLEQVTASLGAKAVLYELFSFNPATLKLYVDLCAGSPFLSGVLINNPGMADELLDTLVLNQARTAEELRDELNELLRGATDPDPILHSFRDKELLRIGVADLLGKTPVRETTAALSDLADTVLNAVCDLVEPQVQLRYGRVTPGCHYAIIGLGKLGGREISYHSDLDLMLVYSEDGTTTRDDPGDTTTNQHYFTELLQKVIQSLSRVGPQGRLYAVDVRLRPTGKSGSLVLPLTEFERYFSEEGCQLWERQAMTRARIVRGSSRFAEPIRTSALGPAWCPDWAGEIRAMRTKLEAKAGAHNVKRSRGGLTDVEFLVQWQQLKHGRDRPEILQPNVWDALDALHAAGLIADDTAVTLHAGYSFLRSVEARLRIVTDRPLIELPESREECEKLARRLGFESSAKFLAEVDRVMAEIRAVFGALT
>NZ_CP042425.1|WP_149108672.1|736949_737342_+|hypothetical-protein
MSNDDALGLTLQLVPSEGEPDAQLLNDLIRLVKQAIVTFPHSMPSVPAMRPADDAERQPLLGLESKIKHHVEQASAASRTLVEQRAVAAQQPDADAELAEESRKKAQQVVAAVQRAIMRGILVKIPDATP
>NZ_CP042425.1|WP_149108671.1|735919_736948_+|hypothetical-protein
MIALDKLRSALVSPQPWSALDRLVRAELSQGRLTRQIREELIGMEEQARDTPGFNDDSEEALHDIIDALAGICPAQYAYQNPPVLPTEEEIAELPLRAQLALAVRCSDIVFPLSQVDTRGNPPIKREACRLAFETLTQNLSAPLPNDFAVAPKLVEAISMEAFEQVNEVTQENGEILTIHSGGHVINASSKVLSTAMFALRSIVQGNAEELSSHVKTCLDLVANATLRYGDFKPYLRRIFDDLMRVSETLGWSDDALVSLDVFGPKFRAMPPRDWPQDMGHTSHSCVPIDLAQNQDIGERELIEETLNIFNALNEYHISRGGQPLTLNDLQPFIPALVRVGV
>NZ_CP042425.1|WP_149108681.1|748582_749812_+|hypothetical-protein
MLELPLPIDPNPPPEPRRVYTVAGIGLAVTAVAAALGIALDASGSGGGPSALSAFRLVLVAGGTLTVGAAVSMRATLPLVWLFGAGAAFLASFGLPEHWDSARMLARVTVYAALTGALLAWAPVKFRYAAVSLAVVYHFFGIFLATTWPDPTPWFTQQVGTRVYLPYIQFMYLKNAYHFYSPEPGSASHLFCLVVYDATDPQTGKPEAKWVTMPSREHNWKDPMGLSYFRRLSLTEQASGSMPQLNPQSDEWRDINARRRAVAQGAQPNVAEIPLAPLDTDPNQYRMPRYDISRYLLPSYAAHLMHAYSTPEKKVASVKIYRLDHPIPNLYQFSQENWNPHHPIGFKPFYLGEFVPTGDGDAVLKDKQDPMLYWMTPILPKLRDAKGREYEDFMSKHAKYEFNWEARMP
>NZ_CP042425.1|WP_149108682.1|749808_751716_+|HTTM-domain-containing-protein
MTPTPDTTPKNAWTRFWFTPTDPTTLGFMRIVTGLLILYVHSVYCLDLYAYFGKHGWYSLSEVDKERHESPTVIPPMFGPEAWQDYVPNGRVPIFPHRLEAVMKFIRKVDADPAVRKGQLAYLIRIQNEVLKSSQPPTTVNPATGLYAMNMSAHLPRNYAAVPNEALDYLNSFYTAEKVRGPQLDAFVNPALRSPKDRVPPAFLNDLDQTGPNSREAVRHEIEQFLAVLATDSTQRKYVIDHLVETGFQNRQSLLEFLLNLPADAAERERQTAYLEKWGAEEHKAYSRGNATFSLWYHISDPTEMAVAHGVILVVMVLFTIGLFTRVTSVLTWLAAVGYIQRTQQVLFGMDTMMNLLLIYLMIGSSGAALSVDRLIARYRASRNSLRRTGGLDGPTRAFLAAPPKSVVAGFALRLVQFHFCIIYLAAGMSKLQGGSWWNTNAFWDTMANPEFTLIHFRWYEDWLRFMVQHRIVYACMAGFMVVFTFVMELGLPFLIWGRLRPYYVVLSALFHFGISLSMGLNLFGLFMMTLVLSFVPGAAIRSQLRGGPNLPRGRIDFDPKQEAHEKAAAAAVMADTDGQLDLAPGEGKAYAVTVNGQESTGAAVPTALFGTLTLLKLARVLKWVPGVKGLFGVK
>NZ_CP042425.1|WP_149108683.1|751858_754066_-|DUF1553-domain-containing-protein
MRSIVLVLLLPTLTLAQEKVKEPEITAEDRAHWSFVPPRKAGVRGQGSGVSSIDSFIRAKTTLSPTADKLTLIRRVTFDLTGLPPTLKEIDDFVADPSPQAYETVVDRLLASPHFGERWATHWLDVVRFAESNGYELDADRPDAWRYRDYVARSFNVDKPYSTFLREQIAGDELAAGKEPREVADLWIATGMHRCGPAHMVSGNLDREMIRQESLTEMVNGVGAAVLGLTLQCARCHDHKTDPISTADYYRVQAFFAAAEYRDVNLATDGEAGAFDKSTAALAKRIGVVKKQVEEIDFPVRAKVVTAKIAAVAPHFREALKADPDKRTAEQKRLVKEIQPAIKVAWDDVLNAMPPGEKAKRDALRQQLFDLEAERPARPAQAWAIADAEKRPPTHVLRRGDASKKGPAVSMAFPRVLTHDGPPPTNRTQLAEWFTSSEQPLTARVIVNRLWSHYFGTGIVRTVNDFGVTSDPPSHPELLDWLACELMDHDWKLKHVHKLIVMSEAYHQTSAVKPNPADPDNRLLGRQNRKRLDAEAIRDAILTAAGTLNREVGGRSVRVPLEPEVYDLIFTEGEPDGLWPVTRDAKQHTRRSLYLFAKRNVRLPILEAFDQPDTLTPCTGRNVSTFAPQALILMNGPFANEQSRELAALLMREKGDARLTLLYRRAIGREPTAAELKTMTAFFSVQAEEIRGRLLARQPVSLPKVIPDGADVAELAALADVCLAVLNSNEFVYVK
>NZ_CP042425.1|WP_168218778.1|754145_755225_-|formylglycine-generating-enzyme-family-protein
MKALLFSVLLVLAGTRLLAADPLKPVAKAANGNDIPHPASTQTTPVTDGGKTIAVPDGMVYVPAGEFTAGTGNSAKKVNLDGYCIGKFSVTNAEYKAFLDDTGTRGTPSYWHGGTYPEGKANHPVAYVSLAKAKEYAAWVGKKTGWKVAIPTADQWEKAARGPKGFLYPWGNSSDVVYADGKLTSKFNFNGVTVAKYLKDEPKKAVTYNNNKSKYFGIKTTVDQIAGYDNSGRATTLSIGANGSVRGWVSHGTYTGFIYTDLFTSLGETGGNTTPVGSYEAGKSGYGCYDMAGNLWNWCDSTIVATNGAEKGKTVNEIRGGSWYAVSNSCRSTSIGEGRAASGAYNTVGFRIVMIPAAN
>NZ_CP042425.1|WP_168218779.1|755310_756342_-|pyridoxal-phosphate-dependent-enzyme
MPHATFTPTELLAVIDRLPRAKLAHLPTPLEEAPRFAGAIGDARVFLKRDDCTGLLLGGNKARHNEFLLGDALDQGCDMVVWGAGVQSNNCRQTAAGCAKLGLECRLYLSRGHYSTEPQGNLLLDYLVGAKVEFTDAKIGPELDALLAAKAAEFRAGGRRPYFWHRPRVVPLAAISYVVCVAEVVQQLAEQNLEPAAIYVSSSGATGAGVALGAKLLGLTCPVRLICPMHWPWHIPTALANDANDAAAMLNLPHRLTAADIDADENFIAPGYGLPSLAGQEAMRLLATTEAILTDPVYSAKALAGLIADVRARKYAKGDVVVFLHTGGVPAIFANPAEVLPPT
>NZ_CP042425.1|WP_149108686.1|756418_757822_+|Si-specific-NAD(P)(+)-transhydrogenase
MPDGESFDLIVIGAGPGGEMGALRTAILGKRVAVVEKEAEPGGASVNTGTVPSKTLRETALALSGLRSRDLYGVDLSIRRGATVDDFLHHERQVRQSEHSRIRGLFEKFGVTVFHGRGEFADPHTVTVHQPDGTTRTLHGENILIATGSVPIRPAEIPFDHNRIHDSDELLNIHELPRSIAVIGAGVIGCEYACMFAALGVETYLIDGREKLLPQLDAEISASLAKAMRALGVQLVLGRAVERFPPPSDGDIELTLSGGTPVHVHHVLFCAGRMCRTPDLKPELAGVQLAEKNRVPVNEHFQTNVPHIYAVGDVIGFPALASTSAEQGRAAAIHMFDNRHPEYAVAQVLPAGIYTIPELSCAGATEDELKAKGVEYAVGRAEYAEVARGKIIGDGSGFLKLLFDKQTRKLLGVHVIGEHATEVVHIGVMAMMTEAGVDLFLRTCFNYPTLGELYKLAALRADFFGLS
>NZ_CP042425.1|WP_149108687.1|757871_758909_-|hypothetical-protein
MTLRRLVGLFAFTALLLSSQLAFAGEGEFDRDGSYKTTNFRTTAPNREMAEKFGDMAEHFRREKAREWLGEEMPNWGQRCPLKVEIRMKDTGGATTFTFGSNGNGRPAVLSQQMHIFGEQKQLLESVLPHEVTHTVLAYYFGQAVPRWADEGGSVLSENENECFTHDIRCRELLNSGRGIRLRMLLGMMTYPKDMIVVYAQGYSICDYLINQHGGRAKFLKFVRAGMNSKNWEAAVHDSYGFESVDDLEEKWIESLRTPPQRVAKAKTNTPTGGTTALASRSSSSEVRMSGLSAVPKLEAPAVVRGVAPDRDERPRQLEAKPANRNNDQPPPIALLLPPEHTPRR
>NZ_CP042425.1|WP_149108688.1|759179_759608_+|hypothetical-protein
MKRIAFDLDETLGVPLISGSLIVGWQLRPGCPELLDRLKAQATLLLWSVSPRRYVEKALTFGLRPWFAESYSWDELPIPWKDVRQLRADFLIDDSPHHRTAAEGVGLGSAYIVVPAYGSPEDIADPFAWAALVEATVLSSDR
>NZ_CP042425.1|WP_168218780.1|759663_760167_+|hypothetical-protein
MHDLRTPPLIQPISGPLIFLAGPIQGAPDWQSEAVRWFAENAPGVTIASPRRAYRPGEFDYAAQVDWETHHLRAAAEDGVILFWLAKEVVPTPGRAYAQTSRFELAEWKVRHERDGTKLVVGIEPGFSGERYICHRFGQDCPAVPLCGTLAETCRTAHELLKASRAP
>NZ_CP042425.1|WP_149108690.1|760227_761145_-|hypothetical-protein
MKSKDLPLKDHASWFAQIWPPLPVWRRLDAAVVLVIAYSLIVKFATSQTDVVLPKWIGDISVVNGILLGVLLGFRNLQAYDRWWEARKLWGQLINDTRNLCVKVKALTTGVPAAELQAFGRLVVGFAVSLRNHLRGGRPLYEVPGFATERANPPHVPLQFAAWIYERIRGWQAGGRLSEINALIIDPHAKALMDVSGACERIRSSPVPLSYRALLRHGTILYLMSAPWFMADQYGYMGVILVALLAYFLLGIEMTAEDVEEPFGKDGDDLDLTRFCETIRKATEQLLGDLDLGDTALSTMAVPKV

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Crispr_ID: NZ_CP042425_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_2

1891571-1891674

Orphan

Consensus_repeat	Method
ACGTCGTCGGAGATCGACCTGCCGCCGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_2

>merge|NZ_CP042425|2|1891571-1891674|CRISPRCasFinder
ACGTCGTCGGAGATCGACCTGCCGCCGATTCGCCAGGGCCTTGAGTTGCCCCCGCCGTCGTCCGCCCTGCATCCCACGTCGTCGGAGATCGACCTGCCGCCGAT

>NZ_CP042425|2|2|1891571-1891674|CRISPRCasFinder
ACGTCGTCGGAGATCGACCTGCCGCCGAT	TCGCCAGGGCCTTGAGTTGCCCCCGCCGTCGTCCGCCCTGCATCCC
ACGTCGTCGGAGATCGACCTGCCGCCGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149109558.1\|1882605_1883307_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109573.1\|1901276_1902020_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109560.1\|1885315_1887802_+\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_CP042425.1\|WP_149109568.1\|1897289_1897724_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109571.1\|1899011_1900217_-\|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	gnl\|CDD\|377253
NZ_CP042425.1\|WP_149109559.1\|1883412_1885212_-\|HSP90-family-protein	unknown	unknown	gnl\|CDD\|237603
NZ_CP042425.1\|WP_149109569.1\|1897801_1898404_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109561.1\|1887888_1889283_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NZ_CP042425.1\|WP_168218861.1\|1881536_1882658_+\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176193
NZ_CP042425.1\|WP_149109556.1\|1879740_1880220_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl\|CDD\|376771
NZ_CP042425.1\|WP_149109564.1\|1894329_1895223_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_CP042425.1\|WP_149109554.1\|1877785_1878514_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|226674
NZ_CP042425.1\|WP_149109567.1\|1896590_1897259_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168218860.1\|1880265_1881540_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109570.1\|1898462_1898795_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109566.1\|1895775_1896432_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP042425.1\|WP_149109572.1\|1900303_1901314_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP042425.1\|WP_149109565.1\|1895291_1895681_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109555.1\|1878606_1879744_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP042425.1\|WP_149109562.1\|1889356_1889584_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149109554.1\|1877785_1878514_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	3.82341e-65
NZ_CP042425.1\|WP_149109555.1\|1878606_1879744_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	3.8689e-151
NZ_CP042425.1\|WP_149109560.1\|1885315_1887802_+\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	7.14807e-116
NZ_CP042425.1\|WP_149109566.1\|1895775_1896432_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.58296e-22
NZ_CP042425.1\|WP_149109571.1\|1899011_1900217_-\|polysaccharide-pyruvyl-transferase-family-protein	gnl\|CDD\|377253	pfam04230, PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora.	1.93267e-16
NZ_CP042425.1\|WP_149109561.1\|1887888_1889283_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.43812e-88
NZ_CP042425.1\|WP_149109559.1\|1883412_1885212_-\|HSP90-family-protein	gnl\|CDD\|237603	PRK14083, PRK14083, HSP90 family protein; Provisional.	0
NZ_CP042425.1\|WP_168218861.1\|1881536_1882658_+\|zinc-binding-dehydrogenase	gnl\|CDD\|176193	cd08231, MDR_TM0436_like, Hypothetical enzyme TM0436 resembles the zinc-dependent alcohol dehydrogenases (ADH). This group contains the hypothetical TM0436 alcohol dehydrogenase from Thermotoga maritima, proteins annotated as 5-exo-alcohol dehydrogenase, and other members of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. MDR, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	5.79754e-107
NZ_CP042425.1\|WP_149109556.1\|1879740_1880220_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl\|CDD\|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	8.63772e-56
NZ_CP042425.1\|WP_149109572.1\|1900303_1901314_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.90572e-07
NZ_CP042425.1\|WP_149109564.1\|1894329_1895223_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	4.26881e-162

>NZ_CP042425.1|WP_149109562.1|1889356_1889584_-|hypothetical-protein
MTIATMATPTFATTPVMGEASRSDMEVVELPLLLPRWQAQALEAAASRRGMTTGQILRKVIGDLFGNLPTTEDKG
>NZ_CP042425.1|WP_149109561.1|1887888_1889283_+|DUF1501-domain-containing-protein
MLLLGQQTQRTCQTLNRRAFVQIGASSVLGLSLADLLRAKESGLNPGSAKAVILVWLWGGPSQLDTWDPKPNAPLEFRGPFATIPTRTPGLRFCELFPKLAGLSDKMTVLRALTTLSSDHGIAGTIGLTGSPAGGTGLDGKPLPGAPRPAVGSIVAKAMANRGRGSAAGIASPFLVIGGKLHQGKKPIIGEGGGPLGPAYDPFRLEYDPVHGTKVPALQLPKDLTPERLADRQKLMESLSEAERKVEKSLSVSTLNDYRSRAFAMLTSAKTHAMFDLSQESPKAVNAYGRTRFGQSCLLARRLVEAGVPFVQVNWSDHVEAEEDSGDGGWDHHYRNFQIMQDRHAMWLDQSLSALLRDLSERGLLESTLVLAVGEFGRDPKVNDKAGREHWPGCYSALMAGGGVVGGRVLGTSDAKAAKPADTPLTPGDLCATVHHSVGLTSEQIAGMGLTSPGRVIEELFGTK
>NZ_CP042425.1|WP_149109560.1|1885315_1887802_+|U32-family-peptidase
MQTSNHLELLAPAGDWEAMRAAVANGADAVYFGLSQFNARARAANFTLDELPKVMDFLHRRNVRGFVAMNTLIFSDELPDAEKFIAAMAAAGVDAVIVQDLGLVQLMKRIAPTLPIHGSTQMTLTEPRGIAFVHKLGVERVVLARELSLNDIRKVTANTDVPVEVFVHGALCVAYSGQCLTSEALGGRSANRGQCAQACRLPYELIVDGERRDLGDKAYLLSPQDLAAYDHIAPLIEAGVISFKIEGRLKGGPYVAATTKTYRQAIDAAVANADFRLPRKDELDLAQTFSRGLTPGFLDGVNHQKLVRGRFPKSRGVKLGTVAGVSRLGVTVRLAEQLPVEELIRAGDGVLFDIGTPQEQEPGGRVWKVEVPKAHPSRRVGFAEVTLTFEANALDHSRIPVGCEVWKTDDPALRKKLEQTYSQDKIARRQPVTATLAGTVGGPLTLTFRDATAVWPGPLEVATKRATTADEIREQLARLGDTPFELAGVTLDLPPNVLVPKSVLNDLRRQAAKSLADTVLTSRRQAIAEANALTSLRKSFTPHSEPRTPHLTVLVRSLDQLDAVLSVRPAMVYCDFEDARRYADAVSRANAAGVPIGVAPLRVWKPGEDGFQSLVVRAKPDAVLVRNLASIGYFREQLPTATLIGDFSLNVANDLTAGILLAEGLERLVPSFDLNWDQFAALMAHADPTRFEAVVHQHMPMFHNEYCVFAHTLSNGKDHTECGRPCDRHRVELRDRTGANFPVLADAGCRNTVFNSVPQSAAEYVGGMRKLGVNWFRVDLLRETPEQIRPLLARYARVIAGQDDGRTAWRELRALNQLGVTRGSLQVV
>NZ_CP042425.1|WP_149109559.1|1883412_1885212_-|HSP90-family-protein
MEHKFQINLRGIIDLLSEHIYSSPEVYVRELLQNAVDAITARGHVEPDHVGDIQMECHLPKGKPPMLVVTDNGIGLTIDEVHTFLSTIGLSSKKGGEQTRSGDFIGQFGIGILSSFVVSEDIVVITKSAKEPTAKPVEWRAKGDGTYTVKELDRDFEPGTQVWLTAKPGREDLFQPDRVKMLARNYGGLLPYPIRLIVGKTVDVINEGGAPWRDRFANEKDRQKVLLAYGREMFGIDFFDAVPIRSEVGKLDGVAFILPFTPAANTRRKHRVYLKNMFLSDAVENLLPDWAFFVQVVVNANDLRPTASRESFYEDSKLAKTRIAIGDSLRKYLIDLAEKRPEKMRRFIAVHHRAIKGLAVEDDEVCRLFLDWLPFETSLGEMTFGDYRQATDRVRYVPNVDAFRQIARVAAAQNLPVINAGYLHDAELLAKVPDVFPHLTVESVDSTTVTQDFDDLTDAELDAVHDFLATAEQILRPFRCSAEAKRFKPAELPALYSTNNEGRFFRSLEQSREVANPLWSGVLDNMSRRDKASLTTAQFCFNFNNSLVQKLATVKDAKKLTRAVQMLYVQALLLGHHPLSAKELAILNDGLLGMVDDSL
>NZ_CP042425.1|WP_149109558.1|1882605_1883307_-|hypothetical-protein
MPPCRLSFAVLLILAGQSAFAQSRSPTAKPAASPTSAILDLVPAAHRDAVSKVMAKPTLTAKYTEDAFQAHEAIYPWLLEHPDRVSLAWQRRDVGCVEIKDTGNGSFSWSDPDGSQLTWQAVAKLTDGVVWYATGKVKAAALLPMVPVKAVAVVKYPSKPTDQKGIVTLTPEASVYLVSESRAANAVMRMAGPAAPKMAEEGAEQLLFFFSGIASHIKENPEKAQALLAAKKK
>NZ_CP042425.1|WP_168218861.1|1881536_1882658_+|zinc-binding-dehydrogenase
MTPRAMLFTGAGQPLQSLPQSTVPPTGAEVRVRMLCCTLCRSDLATYTGQRIEPTPTILGHEVVGEIESFGPAANRSDATGQVASIGDRITWAIVAACGSCFYCERDLPQKCERGVKYGHHRTSPDHPNGGGLADAITLVPGTEWFRVPDNLSTPVASLANCAGATVAAVLEAAGPVAGQTVLIYGAGLLGLLACAMIAAHGARAVIAVDPDRGSRERAIAFGATHTLDPNDPAFDSDLREIVGPRGGDVALELAGRAETVGACLGRVRTGGVVVLAGTVSPTPAVSLDPQQFVRRMLTLRGIHNYQSRHLRAALDFLAGPGKVYPLESLIAETFPLDRVVDAFSAAQHHTGRRVAVTSSSPPEVPGPSRDSL
>NZ_CP042425.1|WP_168218860.1|1880265_1881540_+|hypothetical-protein
MTAPPESRLPVTPWRVTVGTVVAAFGTYFCMYAFRKPFTVATYSDIEAVGGVSFKTVLVAAQVGGYMVSKFVGIRFVAEIEPHRRVRSLLVQVGLAEVSLLLFAVTPAPFNAVWLFTNGLMLGMIFGLIMGFLEGRRNTEALLAALCTSFIVADGAVKSVGSLMLTAGVPQLWMPFVTGLLFVPPLVIGCAILRGVPPPNAADIAARAERPPMSVADRRRFLRRSGVGLGLIVFMYVMVTILRNIRADFAAEIWAGLGVAQAPGLFTWPEVVVALGILVLNGSMVFVRDNRTAFFLALGLSWLGLCLTAAVVQGLGSVAISPFLFMVLLGVGLYLPYIAVHTTVFERFIAITRDRGNVGYLMYLADAFGYLGYVAVLLSRQLFQYRPEDGILPFFRTLCTTAAVAGAAALIPAAIYFRRLRSSP
>NZ_CP042425.1|WP_149109556.1|1879740_1880220_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MSGVTVNVPDLAGTEAFGRQLGALLFPGAVIALIGQLGAGKTHLTRALAEGLNVRNPMAVTSPTFVLIHEYTARLPIYHFDAYRLGSDREFLDLGADEYFHGDGVSVVEWADRVPGAMPHERLEIRIDVLNETARRFTLRAFGERYQRLLTAVNAEPTS
>NZ_CP042425.1|WP_149109555.1|1878606_1879744_+|peptide-chain-release-factor-2
MLNPELRRQTEELTAGLAQLRRSLDIAGKLSQREGFEAKMSEGNFWDNPDAAQKTIQKVKVLNVLLKPYEDLAKSADDLNAMMELAAEDASFATEMEGELAKAMKKYEAFELQAMMSGKQDACSAIVTIKPGAGGTEACDWADMLYRMYVRWAQKHGFGVEEMDKEPNLEAGIQSVQFRVAGEYAYGYLQSEIGVHRLVRISPFGDGGTRQTSFAAVDVTPELDDTIEIEIPEKQLEMQTFCSGGPGGQHQNKTQSGVRLIYNYKGQEVRGESRTERSQPKNYANALALLKARVYQIEEQKRLGDLANRYDAKGEIAFGSQIRSYVMQPYTLVRDEREGIELKTPAIQATLDGDLEEFMYAYLRHRTAKAHKASAKAS
>NZ_CP042425.1|WP_149109554.1|1877785_1878514_-|SDR-family-NAD(P)-dependent-oxidoreductase
MGKLAGKVAVITGGGSGVGKAVAAAYLAEGAKVVISGRDKAKLDAAATELGGDVLTVRCDVALAAECEALIQSSTRHFGKVDILFNNAGANLKNRTIRELTPEAWDQLIRTNLDGTFYCMHYVLPQMFERRDGVIVNLVSVAGKRANPLGGAAYVASKFGQGGLGMCLSNEERESGVRVSNVYPGEIDTPILAHRPKPVTEEHRAVILKPEDVANAVLFVTTLPPHVSIPELVIKPTVHPFW
>NZ_CP042425.1|WP_149109564.1|1894329_1895223_-|4-hydroxy-tetrahydrodipicolinate-synthase
MQTRGELFAGVTVAIVTPFKDGAVDWDELGKLVDWHAEQGTDGLAPCGTTGESPTLTHDENERVVAFVCERARGRVKIMAGTGSNSTSEAVRMTKAAKKAGATGTLQVGPYYNKPTQEGYFRHFGAVAEACDLPQVIYNIPGRTGSNILPETIARLAEAFPHVVAIKEATGSLDQASQVAALCDLTILSGDDSLTLPLMSIGGKGVVSVVGNIVPKDMMALVRAFAAGKFDEALKLHRKLFPLCRDMLSVATNPIPVKTAMKLLGRGNGEMRLPMYPMDAAGDAKVRQTLVNYGLLK
>NZ_CP042425.1|WP_149109565.1|1895291_1895681_-|hypothetical-protein
MKELWYSMPSPNATTTSSRGSRLIAFVCAMAGMCAALFAVLVTLGSPDAAVSVTETVAMQFTDFTEPGTITVRSFGFELYSRRVANPSILEIECAFWGMLPITFILVSAVIDWYFGRCINRPSAKPGSR
>NZ_CP042425.1|WP_149109566.1|1895775_1896432_+|sigma-70-family-RNA-polymerase-sigma-factor
MSTDSDRLLVQHIRAGGAKADAAWEELVARYEGRLGAFVRKRLRDHGTSDDVVQETFIGFLNSLANYDDKRDLQTWLFTIASHKVTDQLRRIGRRPFQTGSEADEEMMGKAADGRQRPASSLARSKERLDLEHDAVARCLRDMIGAFRQKGEFQRIQVLELLFVKGWPNKEVAAFVGVNEQQVANYRFAAVKKLTEQMKSAGLPVEVFPELTLPDDLN
>NZ_CP042425.1|WP_149109567.1|1896590_1897259_+|hypothetical-protein
MLKLPDEIMAAPSDTTIPGLAQRRVWKAPDVTSHSLVVLTLPRLYLTPMTGSPKTEVISQLETVRAVDSFLGPLATAIDLYTVRRVKLDLKDHTVTIDHQMANSPNGRTVIRFADGRVADSFFAKIWRRLGDGYQLKTFAPEWWTLARLPIVFIAAVIVFTAITAMVLNAISDTGIDQHGIARVLPNWRIVCAVGGGAVAAAQMWLYRMASRPPERLELQQL
>NZ_CP042425.1|WP_149109568.1|1897289_1897724_+|hypothetical-protein
MTRDELVEMMERIPELDHSKVQFVMRSGAMLSLDILVRLEPTYLVMRGREAGNQDEGRGFFLPYADIQFLKIERVMTLAEMEAMFADRLASVKRAGRETRSDSITETPPPPSAPLDPAAIAKQNLLDRIRAAKSVITNGRPASK
>NZ_CP042425.1|WP_149109569.1|1897801_1898404_+|hypothetical-protein
MRSPDTSRPEFVAPPPSAHDTLDAQGLVNTDLVQGVFAARDLEWETELLTRLSEQEQRFREFTRRKFQADPHGVLGLAVRMVQAIDADAACHAERATLIRANLPATRTAAAPFLRQAEALPKPPPPRTVLGFTVSTPRVEPVVRSSAAALVRELPTVIESYLLLLGNGFATGHAAAKWVETSSVFTRQLTKLTRHITDAG
>NZ_CP042425.1|WP_149109570.1|1898462_1898795_+|hypothetical-protein
MVVFSTRWLCQQFDKSALFSALSPDVVTGRFKNDATWEGRSDWQLCSSLGRPDNVVPAEKCDVFFFLPPRAYVKVYIYNSIDLAAYIDRSGTVVATDVPVRKIARQHSLD
>NZ_CP042425.1|WP_149109571.1|1899011_1900217_-|polysaccharide-pyruvyl-transferase-family-protein
MNRRTFLATAAATLAASPGRAADPKGKKVLLRSSWQTVNIGDIAHTPGMLSLFEKHRPQDEVTLWPNALSPEVETLLTTRFPKLRLAKTKAEQDAALTACDFFLHGSGPGLVGAKEALRAKEAGKPYGFAGVTLSDAELKSHRDLLAGAKFVFTRDGDSLKALKATGIAGPKMEFGPDATFALDLRDDAAAGKLLKEHGLEPGQYLCAVPRLRWTPYWEIRDTVKPNPKRSAVNEAFAERDHAKLREGIIAWVTQFKRKVFLVPEMTYAVERLGPLLYDPLPAAVKPNVAVLDRYWLTAEAASIYAQAAAVASFENHSPIMALAAGVPAMLLRQPTDTRKGQMWRDVGLDRWLFEIDDASGKEIAERIVEIGRDLPAARTIAEKAHTFANERMAAMVAEVG
>NZ_CP042425.1|WP_149109572.1|1900303_1901314_+|CPBP-family-intramembrane-metalloprotease
MTDLRAEAVAMATAAACVAAAAVPAGAACWWLARRCREPVVPRYRKGFSRWDGFDALVLFCVCTMLSTALAGVLDSAGYFRPIFNDVRPGADAAEAVRFDYQNRRNTIAGLIVMPGVMAGFAWWKRFGWKELDRERVRRFIADVSAGVGGWCVLMPLTLVVHFVVNAISQQLDVTPDEHPLKSVKLQTAFDVALFLAGACVVAPFFEEMAFRRVLIPWAARRLYRPWILMAFAALMAYSRGGGHSLVGPLAFVGAAALALFALERVARRSLRPAAAILATATFFAAIHASVWPTPIPLLMLGVGLGWIVLRTKSVTAAVVTHGLFNAVSAVFLLRG
>NZ_CP042425.1|WP_149109573.1|1901276_1902020_-|hypothetical-protein
MTWEELFQRPKDFVADEWFARIAATLLNASRLIVAGEPHRLTEVELYYHGPAHEDPFAHRDPVQQQVGVWYFHRTGGTYRGGSFKGLDLAFGSPGVFSGLLFRGLEDSAGRFVDGPSLLVDHILKKTGAKSVRELDAGIADRVAWDASSPVHLMRLPEPESRPIYRAARVGLTLKRATLGDPRPQFLRKDYRFLTEPRHTKKGKAHIVRGLHQQGVPIERIRELTGSPLASIRRYLTLAAGTPPTLR

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Crispr_ID: NZ_CP042425_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_3

2449108-2449209

Orphan

Consensus_repeat	Method
TCCAACGAAAAGTGACTGAGAATTAATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_3

>merge|NZ_CP042425|3|2449108-2449209|CRISPRCasFinder
TCCAACGAAAAGTGACTGAGAATTAATGCGCGTGCAACTCTACGCACGTTCTGCCGGTCGTTCGCCCGGGCTATCCAACGAAAAGTGACCGAGAATTAATGC

>NZ_CP042425|3|3|2449108-2449209|CRISPRCasFinder
TCCAACGAAAAGTGACTGAGAATTAATGC	GCGTGCAACTCTACGCACGTTCTGCCGGTCGTTCGCCCGGGCTA
TCCAACGAAAAGTGACCGAGAATTAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149109982.1\|2441763_2442759_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187673
NZ_CP042425.1\|WP_168218903.1\|2436844_2437072_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP042425.1\|WP_149109994.1\|2456243_2457134_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP042425.1\|WP_149109987.1\|2448450_2449041_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168218905.1\|2447584_2448205_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP042425.1\|WP_149109984.1\|2444141_2446286_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149115461.1\|2450684_2451131_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl\|CDD\|235777
NZ_CP042425.1\|WP_149109991.1\|2453415_2454243_+\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|274447
NZ_CP042425.1\|WP_149109995.1\|2457168_2457660_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223532
NZ_CP042425.1\|WP_168218904.1\|2442760_2444056_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340817
NZ_CP042425.1\|WP_149109992.1\|2454239_2455514_+\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP042425.1\|WP_149109981.1\|2440033_2441767_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236443
NZ_CP042425.1\|WP_149109980.1\|2438525_2439848_-\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|179486
NZ_CP042425.1\|WP_149109988.1\|2449248_2450598_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307
NZ_CP042425.1\|WP_149109993.1\|2455518_2456247_+\|DUF4058-family-protein	unknown	unknown	gnl\|CDD\|379094
NZ_CP042425.1\|WP_149109996.1\|2457731_2458244_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP042425.1\|WP_168218906.1\|2452775_2453387_+\|bifunctional-precorrin-2-dehydrogenase/sirohydrochlorin-ferrochelatase	unknown	unknown	gnl\|CDD\|224562
NZ_CP042425.1\|WP_149109985.1\|2446619_2447588_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109979.1\|2437032_2438232_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP042425.1\|WP_149109989.1\|2451297_2452419_-\|M24-family-metallopeptidase	unknown	unknown	gnl\|CDD\|223085

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149109982.1\|2441763_2442759_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187673	cd09813, 3b-HSD-NSDHL-like_SDR_e, human NSDHL (NAD(P)H steroid dehydrogenase-like protein)-like, extended (e) SDRs. This subgroup includes human NSDHL and related proteins. These proteins have the characteristic active site tetrad of extended SDRs, and also have a close match to their NAD(P)-binding motif. Human NSDHL is a 3beta-hydroxysteroid dehydrogenase (3 beta-HSD) which functions in the cholesterol biosynthetic pathway. 3 beta-HSD catalyzes the oxidative conversion of delta 5-3 beta-hydroxysteroids to the delta 4-3-keto configuration; this activity is essential for the biosynthesis of all classes of hormonal steroids. Mutations in the gene encoding NSDHL cause CHILD syndrome (congenital hemidysplasia with ichthyosiform nevus and limb defects), an X-linked dominant, male-lethal trait. This subgroup also includes an unusual bifunctional [3beta-hydroxysteroid dehydrogenase (3b-HSD)/C-4 decarboxylase from Arabidopsis thaliana, and Saccharomyces cerevisiae ERG26, a 3b-HSD/C-4 decarboxylase, involved in the synthesis of ergosterol, the major sterol of yeast. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid sythase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.54278e-90
NZ_CP042425.1\|WP_168218903.1\|2436844_2437072_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	9.86994e-10
NZ_CP042425.1\|WP_168218905.1\|2447584_2448205_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.45659e-14
NZ_CP042425.1\|WP_149109979.1\|2437032_2438232_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.5993e-06
NZ_CP042425.1\|WP_149115461.1\|2450684_2451131_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	6.04831e-50
NZ_CP042425.1\|WP_149109988.1\|2449248_2450598_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NZ_CP042425.1\|WP_149109991.1\|2453415_2454243_+\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|274447	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB. Members of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction. [Energy metabolism, Electron transport, Protein fate, Protein modification and repair].	3.86752e-13
NZ_CP042425.1\|WP_149109995.1\|2457168_2457660_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	4.96039e-08
NZ_CP042425.1\|WP_168218904.1\|2442760_2444056_-\|glycosyltransferase	gnl\|CDD\|340817	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.	1.39641e-59
NZ_CP042425.1\|WP_149109992.1\|2454239_2455514_+\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	8.16207e-151
NZ_CP042425.1\|WP_149109989.1\|2451297_2452419_-\|M24-family-metallopeptidase	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	3.17388e-98
NZ_CP042425.1\|WP_149109980.1\|2438525_2439848_-\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|179486	PRK02862, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NZ_CP042425.1\|WP_149109984.1\|2444141_2446286_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.62088e-110
NZ_CP042425.1\|WP_149109994.1\|2456243_2457134_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.37077e-32
NZ_CP042425.1\|WP_149109996.1\|2457731_2458244_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	6.25686e-94
NZ_CP042425.1\|WP_168218906.1\|2452775_2453387_+\|bifunctional-precorrin-2-dehydrogenase/sirohydrochlorin-ferrochelatase	gnl\|CDD\|224562	COG1648, CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism].	6.97158e-46
NZ_CP042425.1\|WP_149109981.1\|2440033_2441767_+\|AMP-binding-protein	gnl\|CDD\|236443	PRK09274, PRK09274, peptide synthase; Provisional.	0
NZ_CP042425.1\|WP_149109993.1\|2455518_2456247_+\|DUF4058-family-protein	gnl\|CDD\|379094	pfam13267, DUF4058, Protein of unknown function (DUF4058). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 244 and 264 amino acids in length.	1.23678e-05

>NZ_CP042425.1|WP_149109987.1|2448450_2449041_-|hypothetical-protein
MPTDELGSLSQKARTKSLRTARIIMLLLGILVFAVNLTTGLMAKTFVDVEIDREVRDLQSKGMVIDQEKLQPLRESAIRAAELASFLAAGVGMILILLGFLIYRAPVACTVTGFVLYLGYWFAAIAIAVSSNDRAEDVGKAFGQAICSGLLVRVIIIFCFVKAIRAAVAYQNEAKARLRDDSNDFDRTPESPFESA
>NZ_CP042425.1|WP_168218905.1|2447584_2448205_-|CPBP-family-intramembrane-metalloprotease
MALKGFFALLVVSIIQTIILAGMSEKDGKAFEHIQLAVFEAVDTVIVLLVWAWCGSARLLSATADRRVFAWVLALPLLAALVGVNVLYHAAIREYVKIEWFRLPEPAGVTLVGVLLECVQPGIVEEFFFRYLLLGVLRRYGGVHGAVLVSAAMFGVCHIHVFLSMPYLFALGVFLGYVRVWSRSLALPVLLHVTHNLAVTWLEEFL
>NZ_CP042425.1|WP_149109985.1|2446619_2447588_-|hypothetical-protein
MIGEVVESRPTGGLWAGFFVVLGLLFGIVFLVAPKKDGWPTVFLPFGIAAGIWLGRDRPTVFRIAEDHLQFEQPTEHMVRFEHLEGVVTSGDREASRTTIQLNHADGVTVIPDRLTVASHELLVFLESKWPRTRSPRIPASLHGYREDQVAKFGEDHIYTFAGRPKMIHRRRSYKGVYAMLGLAAAAVVMGVAGRVTQGNFDDAWMGGGLGVALFGLFIALILFLSGRSLQGDAQAHSGLVITPVGLALVQGDSKGKLRWDEVKAIEYPPVKRMGVTRTANSKHGIGLLVDGAYIVILDYYNRPAPVIYNILCDYWNGGRPA
>NZ_CP042425.1|WP_149109984.1|2444141_2446286_-|protein-kinase
MGSNLHARESTQSRGVPTRRMNGGHPLADTVPASCDTPLPAIRLSGDYQLIRVLGRGGMGIVYQARQSGLKRDVAYKILTVLGSTDPETLERFRSEAETLGKLQHPGIVQIFDCGTENDSPFLAMEYVAGGSLADKLKDGRPSPREAAALIATVAGAVGYAHARGIIHRDLKPANILLTPEGQPKVADFGLARDLATEHLTQTGMIAGTPTYMPPEQLTGKKDLTPAVDVWALGVLLYEMVAGTVPFSGDNPQQILTNILQHEPVALRAWQPNLPRDLETICRKCLHKDPQRRYADGQDLADDLTRFLEGRPILARPIGRLEKGWNWCRRNPLTTGLTVALGVILTVATGVSLAFAGQAEDERRNAVAAADAAVLAANGERKLRQQAESAAEAERKARQDAEAVTAMLEKILISIGSGFGAESLKTMQQQIAQLADVAKNDTGDPLRRARVLFTLALARRSFGEFVEAIVLMEQSLALRQQHLEPRHPELIKTATEMTYTYIHAGRGADAVRVIEPIVEAARATLAPDSAEFLNQLNLLRMSYRHAGRRAEEAAIEEQILAICVKKFGEDHQETEWVRVNLAKYRLPSADCHTVLPVLQKAYARFQKHCRPTSSEVLWTRSQLGLCLLACSRPAEAVPHLKGAYDYNRSQYGPDHLFIYYAARDLGTAYEECGRYRDAVPLWWRMLMHPYATGDAERFTRYAVKLVEDVTLMCW
>NZ_CP042425.1|WP_168218904.1|2442760_2444056_-|glycosyltransferase
MRIALYCPDMTGHLNPMTTLGRELARRGHEVSVFGLPPARRFADRAGLGYVGIGHADYETHVAPGRVRLAELTGLAAMKLTGRLLADIEIVGFRELPAAFRAQGIEAVVADQVSSAGGCVAEVLGLPCALACNALALYQEAGVPPPVLPWAYRPGLLPRLRNRLGNTALRWAVAPVRREIAAYRAAHGLSPVPDANVTTATGLVQVAQQPAFFDFPRDHLPDHFHYTGPWHEPIRDGEEPFPWDQLDGRPLVYASLGTLQNRLKHVFTAILTACETLPVQVVLALGRRDAVWDGPVPANALVVGFAPQLPLLDRAAAVVTHAGLNTALESLARGLPMVCVPVTNDQPGVAERVRWLGAGEVLRPGRVTAARLRPMIEAIVNQPKYREAAMVCRKQLELSPGVRGAADLVEEAFQTKRRVRRADWEGRLPVA
>NZ_CP042425.1|WP_149109982.1|2441763_2442759_+|NAD-dependent-epimerase/dehydratase-family-protein
MKALVTGGGGFLGGAIVRALRARGDTPISFTRSRYAWLDEIGVQQRLGDLTDLDAVDQAVAGCDVVIHVAAKAGVWGRYADYVATNITGTENVLAACRTQGVRKLVYTSTPSVVHTGVDIAGENESLPYAKHFDSYYPQTKAKAEQAVLAANGSDLATVALRPHLIWGPGDPHLIPRLLARARLGKLKRIGTREVKIDLTYVDNAADAHVLAADKLEIGSPIAGKAYFISNGDPVVMWTFLNRILADAGVPPVTKTVPGWVARLTGRALEAVYGLFRVAGEPSLTLFVAKQLSTSHWYDISAAKNDLGYDPQVSIEEGLKRLAASFKPHPG
>NZ_CP042425.1|WP_149109981.1|2440033_2441767_+|AMP-binding-protein
MTTPDVNVSSHLAILAAVEPARVALHSARAGTHRTFSQLHSESDATAHGLTALGIGPGTRVALMVPPSLEFFSLTFALLKAAAVPVLIDPGMGIRRLGDCLNEAEPEVFIGIPKAHVARRLLGWGRRTIRTTVNVGRGRFFCTRSSRELPLTFTGKGEYARPPVTANDPAAILFTSGSTGLAKGAVYTHGIFTAQVEMLKAEYGIAPGEIDLCTFPLFALFGPALGMTCVIPDMNPSRPATIDPPKTLSAVRRFAVTNLFGSPAVIRRLGDSFKEGADTLTSVKRVLSAGAPASPHALERFSRLLPDGVQIFTPYGATEALPVANIGSDEILAETRRLTERGHGVCVGRPFAGMTVRIIRISDEPIAEWDESLCVPDGEVGEIVVRGPVVTKQYWHRDAATKLAKITDPATGEVLHRMGDVGYFDDRGRLWFCGRKSQRVVTPHGTLFTDMVEPIFNTEEGVSRTALVGVVRDGVTHPVLCVEPTFRTRAGLLEVSKNLKQNEERGTRFDPRFESNPRGYLTFHLYAEVKRITPTINAILIHPKFPVDVRHNSKIFREKLAEWADGQLPRKWNGGRV
>NZ_CP042425.1|WP_149109980.1|2438525_2439848_-|glucose-1-phosphate-adenylyltransferase
MPEVLSLILGGGRGSRLFPLTKSRAKPAVPVGGKYRLIDIPISNCINSRLNNIYVLTQFLSVSLHRHIANTYKFDMFSKGFVEILAAQQAYDEQIGWYQGTADAVRQNIAYINREEPDEVLILSGDQLYRMDYQQLIETHRKSKAEVTIAAIPVPEEQTAGFGLMRMDDSGRVLSFTEKPKTAEARKPYYTPSTWIEKMGIPSKGRNYLANMGIYLFNTDKLIEMLNAPVPDKLHNAMLLPHDFGSNVFPNHVADRHIQAHLFDGFWEDLGTIKSYHETSLALGEPNPPFDFFSPEGPIFTRMRNLPASRINGAALESVTIADGCVIGAGSSVKHSLIGVRSVVGANCHLKDVVMIGSDGFETQVELEENRRLGRPHLNIGEGCRIERAMLDKDCRIGQGVRIRDHDADADYDDPAGRFHIRDGIVCVPRGAVIPDGLEI
>NZ_CP042425.1|WP_149109979.1|2437032_2438232_-|tyrosine-type-recombinase/integrase
MSRRQPAPYFKKSHKAWYVQIGTKQHRLSDDYAEALARCAELLKAHKKAERFIVPSEPLPFTLGQLTSEFLRVAFKDRSPRTRGWYEEKLTPFVRHLGETFPASHLKPLHVEQWVAVHPDWARGTARGVWQAVQRLMRWAERSGRTPHSSVCDYAKPKAGKRSVVISPAEYQRVREAIRSERFLDLVTLAWEIGARPQELLKLEARHFDSANRRFVLPPEEAKGDRWPRIIYLTEAVVPLVDRLVAERPAGRLLLNEAGKAWTPMSVNCQFVAVQHRMGFAAMRERAIEVREEAIQMKLLSLRPSRVVNGREEAKSVAELREEARLKCRRELAQTLAPKYCLYHLRHSWLDRMLKSGVDAMTCAILMGHRDPSTIAKTYQHLSQSPDHLRAALNKKPPG
>NZ_CP042425.1|WP_168218903.1|2436844_2437072_+|helix-turn-helix-domain-containing-protein
MTPSLTVKEAATCLRLSPAAVYGLCAAKLLRHQRVGVGRGKILIPPDAIDEYLARGTVRSAESHPGGFLFSAARK
>NZ_CP042425.1|WP_149109988.1|2449248_2450598_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFQRILVANRGEIALRIIRACRDLGIEVACVYSEADKDAPYLKLADQAICIGPGPAVDSYLRVDRIIAAAEITNAQAIHPGYGFLSENSKFASICRDCKIEFIGPPPEAMDAVGNKEKGKQLAKKAKVPTVPGSDGLVTSDEEALKFAHQVGYPVLIKASAGGGGRGMRVARNDITLVSGLASARQEAESAFKDGSVLLEKYLDQPRHVEVQVLGDRYGNVIHLYERDCSMQRRHQKLVEESPAPNLPEKVRDNICDAAVRLARAAGYYSAGTCEFLVDKDNNFYFIEVNARVQVEHPVTELVTGVDLIREMIRVAAGEKLRYRQKDIVLRGAAIECRINAEDPANNFRPSAGTITKWQPPGGPGIRMDSHVVTGYRVPPNYDSMVAKLLVHQPTRDEAIAVMRRALREFTVEGIATTIPIHQQIMSTAEFINGTVDTTFIERRLMAGK
>NZ_CP042425.1|WP_149115461.1|2450684_2451131_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MVEFLVKLMADRDLSEIDLHEGEHRIRLRRGARVVTAHATTIAPPPAVPHAAAAQAPAVAPAAATPKSNLHEIKSPMVGTFYAKPSPDKDDYVKVGSKVKPDTVVCKLEAMKLFNDHPAECTGTIAEVCVKNGQPVDFGTVLFRVELG
>NZ_CP042425.1|WP_149109989.1|2451297_2452419_-|M24-family-metallopeptidase
MNYFTHRRNSLLRDLKKDNLDALLITQPVNVTYLTGFMGDSSYFVLTAKHAILVSDDRFSQQVREECPDLEVHIRPHNKTTPEAAGEVLTKLGAKAVGVEADHMTMALAEAFKEYAPKSTLAPVRGAVEALRALKDASEVEAIKAAIRVAERAFVMFKSTLRETETERDMVAAVENFVRRAGGDCTAFPPIVAVGERGALPHAPPTTKPLNDGSKLLVDWGAVLNGYRSDLTRTLKSPFEIAPTRRNKSERVGYNFEKIHDIVLKAQDAAIKTVREGVPAKDVDAAARKVITDAGYGEYFTHGLGHGIGLETHEAPRVRQNSTDTLESGMVITIEPGIYIPGWGGVRIEDDVLVRRDGGLVLSNLPRDWATGM
>NZ_CP042425.1|WP_168218906.1|2452775_2453387_+|bifunctional-precorrin-2-dehydrogenase/sirohydrochlorin-ferrochelatase
MLDLRGKRVLVVGGGAVGRRKALSAFSAGAAVRVVALESLHEEFAAHVSIEWIQANYHADHLQGMCLVFAAATPAVNDRVALDAIRRGVWVNSASDPTAGDFTLPAVVRRGELTLAASTGGAAPALARRIREKLEREFDEHLATWIRLLEMIRPTVRESIADPELRRALLDDFADWPWLERLKAEGEDATRRLMEQRIRAAAL
>NZ_CP042425.1|WP_149109991.1|2453415_2454243_+|cytochrome-c-biogenesis-protein-CcsA
MSLSTLQGVSHTCFGLSYLLAFTLELARIRWPRTGLRTAGLVVGAVGLFTHSAYLAIHHPSLAAPYGSLLLLAWVLAVFYFYGSLHHARQAWGIFVLPVVLGLVALSLVIVSLSGTDDVDVPVWLVGEKFWGAIHGLLLLLAAVGLSVAFLSSVMYLVQARRLRTKANPLGAVKILSLERLEEMSRRAVNLAFPMLTAGVLLGMLMLNHEPPSTLVTPSLKVLGSYGLILVVAMLVYMRYAAHVSGRRLAVWSILAFVLLVVVLMAAHPFVEGGK
>NZ_CP042425.1|WP_149109992.1|2454239_2455514_+|glutamyl-tRNA-reductase
MNLRIVGCNFRTANVDVRERLAFPPDLHARASAELAARFGCEVAILSTCNRVELFLARPHGATVLSTELATEFLGEVHHVPPETLTPHLYSHADADATRHLFRVAASLDSLIVGEGQIAGQVKQAFEAAQQLATTGPLLNALFPHALRTAKRVRTETGISLGHVSVSSVAVDYVKQVFDHFGDKTILVIGAGKMGRLTLKHLEELKPGRILVANRSPEKAAEVAAGCGGTPIPWDKLDDALGEADIALSTTGAGEPIVSQKRFDKQVRPKRRHGRTLVVLDIAVPRDFDPAIHDGDRVCLFNIDDLTRIREQTIAERQSHIRPAEAIVAAEVKNFTDDWQRRKNGPVIQQLRSEVDKVRDEVLTPLLAKLNGKLSLAEKEQVAAAFRLFQNKLLHGPIAALQDASKEGDRGTLIEAMKKLFRLG
>NZ_CP042425.1|WP_149109993.1|2455518_2456247_+|DUF4058-family-protein
MPIHDWTIVEAGIYHAFHHSWIAFLSAALNDGLLPPDHYALPEQDVGGYVADVVALHGRSSAPSPSPPTATVMAVAPLASVISQADPARTRKRRSHVAIKHVSGYETFAIIELVSPGNKDNRNGFLVFVQKACDLIERRINLMVVDLFPPGPRDPQGIHAAIWGELAHDDFTPPPDKPLTVVSYEAAFPPKAYLEPRAVGDRLPDMPLFLEPGRHIQVPLEATYQTTWNATPQRWRAAVESR
>NZ_CP042425.1|WP_149109994.1|2456243_2457134_-|DUF1559-domain-containing-protein
MPTGVQRRNVIVLVGIAILTMGLVVTGIVAMRASANRAMCANNLKQLGIGFHGWHDTSGGLPPGFVTTPNGPNDWGPGWAWGSLLINYLESSDYYSRTKQNLPIEVVENKYSRTIPFRFFRCPTGSAPTTFMLYHRTANGDPLAPICDIAASNYVGVCGTTEPHVEGDGVLFRDSKVKFDDITNGLSNTLLVGERSFRTGESTWVGAVAGAGHFPPAGSGFAPELRDSANFVLGTAGGMTDGATKPKQANHFSSNHRDGVNFAMCDGSVRTLNKSISGDVLRAMATQAEKDNGGEN
>NZ_CP042425.1|WP_149109995.1|2457168_2457660_-|GNAT-family-N-acetyltransferase
MPNLTIRPANLADAAVIAEYNRRLAWESEHVRLDEAVLLAGVTAGLEDPHKGFYTVAERGGEVVGQTLVTFEWSDWRNGWFWWIQSVYVREDARRGGVFRALYQHVQERATADPTVIGLRLYVEADNARAKQTYRSLGMTDTSYGLLEIYPLPGRAKHLGGLD
>NZ_CP042425.1|WP_149109996.1|2457731_2458244_+|adenine-phosphoribosyltransferase
MELNPFIRDIPDFPKPGILFKDITPLLMNATAFQHSIDLLSIQFAGQKIDAIAAAEARGFLFAAPLALKLHKPLVPLRKPGKLPYRTYSLKYDLEYGQAELHMHVDGVELGQRVLLVDDVLATGGTMAAGGQLIEQAGGTVAGCAFLVELAFLNGRAKLPNYDVFSLLTY

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Crispr_ID: NZ_CP042425_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_4

3078725-3078823

Orphan

Consensus_repeat	Method
TTCGGCCCTGAAGGGGTCGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_4

>merge|NZ_CP042425|4|3078725-3078823|CRISPRCasFinder
TTCGGCCCTGAAGGGGTCGTTCAGTCAGCCCAGGTCGGAGCGAAGCGGAGGCCTGGGTACGGGACCAACCCGCATGTTCGGCCCTGAAGGGGCCGTTCA

>NZ_CP042425|4|4|3078725-3078823|CRISPRCasFinder
TTCGGCCCTGAAGGGGTCGTTCA	GTCAGCCCAGGTCGGAGCGAAGCGGAGGCCTGGGTACGGGACCAACCCGCATG
TTCGGCCCTGAAGGGGCCGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149110487.1\|3082750_3083296_+\|DUF2721-domain-containing-protein	unknown	unknown	gnl\|CDD\|378544
NZ_CP042425.1\|WP_149110481.1\|3072629_3073448_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149115493.1\|3084393_3085623_+\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_CP042425.1\|WP_168218971.1\|3087709_3088861_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP042425.1\|WP_149110478.1\|3069289_3069487_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110485.1\|3079696_3081427_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP042425.1\|WP_149110479.1\|3069566_3070010_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110492.1\|3088958_3089348_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110482.1\|3073580_3074228_+\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|368908
NZ_CP042425.1\|WP_149110484.1\|3075732_3077292_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149115491.1\|3077401_3078700_+\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NZ_CP042425.1\|WP_149115490.1\|3074798_3075578_-\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153097
NZ_CP042425.1\|WP_149110488.1\|3083365_3084241_+\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|223730
NZ_CP042425.1\|WP_149110483.1\|3074244_3074802_+\|exonuclease	unknown	unknown	gnl\|CDD\|176648
NZ_CP042425.1\|WP_149110486.1\|3081498_3082530_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381317
NZ_CP042425.1\|WP_149110477.1\|3067377_3069243_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110480.1\|3070160_3072458_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP042425.1\|WP_149110490.1\|3086845_3087655_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237001
NZ_CP042425.1\|WP_149110489.1\|3086047_3086833_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273567
NZ_CP042425.1\|WP_168219516.1\|3078937_3079207_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149110487.1\|3082750_3083296_+\|DUF2721-domain-containing-protein	gnl\|CDD\|378544	pfam11026, DUF2721, Protein of unknown function (DUF2721). This family is conserved in bacteria. The function is not known.	2.45329e-11
NZ_CP042425.1\|WP_149110486.1\|3081498_3082530_+\|aldo/keto-reductase	gnl\|CDD\|381317	cd19091, AKR_PsAKR, Polaromonas Sp. aldo-keto reductase and similar proteins. The prototype of this family is an uncharacterized aldo-keto reductase from Polaromonas sp.	0
NZ_CP042425.1\|WP_149115493.1\|3084393_3085623_+\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	6.36008e-165
NZ_CP042425.1\|WP_168218971.1\|3087709_3088861_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	4.09843e-28
NZ_CP042425.1\|WP_149110485.1\|3079696_3081427_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.05769e-24
NZ_CP042425.1\|WP_149110482.1\|3073580_3074228_+\|DUF1080-domain-containing-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	2.66289e-44
NZ_CP042425.1\|WP_149110484.1\|3075732_3077292_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.96437e-108
NZ_CP042425.1\|WP_149115491.1\|3077401_3078700_+\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	7.45468e-16
NZ_CP042425.1\|WP_149115490.1\|3074798_3075578_-\|ferritin-like-domain-containing-protein	gnl\|CDD\|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	6.27801e-05
NZ_CP042425.1\|WP_149110483.1\|3074244_3074802_+\|exonuclease	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	3.06245e-06
NZ_CP042425.1\|WP_149110488.1\|3083365_3084241_+\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	1.82151e-25
NZ_CP042425.1\|WP_149110480.1\|3070160_3072458_+\|hypothetical-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	0.000658431
NZ_CP042425.1\|WP_149110490.1\|3086845_3087655_+\|hypothetical-protein	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	0.00124147
NZ_CP042425.1\|WP_149110489.1\|3086047_3086833_+\|hypothetical-protein	gnl\|CDD\|273567	TIGR01349, PDHac_trf_mito, pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form. This model represents one of several closely related clades of the dihydrolipoamide acetyltransferase subunit of the pyruvate dehydrogenase complex. It includes sequences from mitochondria and from alpha and beta branches of the proteobacteria, as well as from some other bacteria. Sequences from Gram-positive bacteria are not included. The non-enzymatic homolog protein X, which serves as an E3 component binding protein, falls within the clade phylogenetically but is rejected by its low score. [Energy metabolism, Pyruvate dehydrogenase].	0.000116899

>NZ_CP042425.1|WP_149115491.1|3077401_3078700_+|PQQ-binding-like-beta-propeller-repeat-protein
MFRCLILALALSSVASAADNWPSWRGPTANGVAASDANPPTKWDEKTNIKWKADLPGKGSATPVVWGDQVFVLTAVPGREAKPEELPKVDRRFETKTEVPHNFYSFEVLSFDRTTGKPLWKKTAAEAVPHEGHHPTHSYAAGSPATDGKRLYVSFGSFGVFAFDLKGEQIWKRDLGRIHSRLGWGEAVTPVVHGDTVILNWDQEDGSKLIALDAATGDTKWEVKRDEKTSWNTPLIVEHGGTTQVLVNGTNRARAYNLVDGKVLWEVSGMTVNAIPSPLAADGVAYIVSGYRGAMAVAVPLDSRGEVAKDGVKWRYAKGTPYVPSPLLFDGRLYFTEANTQLLTVLDAKTGKPLQERERLQRVGSFYASPLAAAGRLYFVDRDGTTAVLSAGDKPEVLATNKLDDKTDASPVAVGKTLYLRGEKHLYAIEEK
>NZ_CP042425.1|WP_149110484.1|3075732_3077292_-|protein-kinase
MADTTHESPHGSTDAAPHDGTQLFQPDVGPSTVMQTSEQLALAAALSAGHQTVPGYQILGEIGRGGMGVVYKAKQIQANRVVALKMILGGSHAGAADRERFRTEIEATAQLQHPGIVRVYEVGEHHGLPFFSMEFCEGGSLARKGGRPQSPNAAAAIVERIARAVEAAHLAGIVHRDLKPGNILMTGDGTPKVGDFGLAKRLDSVDGHTHTGAVMGTPNYMAPEQAAGKAKAVGPQADVYAIGVILFELLAGRQPFQAEGLPELLQKVVHNEAPSLSEFRRDAPRDLETICQKCLAKDPAHRYPTAGALADDLRRFQSGESISARQLNVVERFAWMLEKSHYDQQFVRYAGFFLWLAPVFFLPELYATFVRFHGWPVWWVMPAYAIRPVLGLSLFLYYGDGRIWPANPAEQHILSVWGSFVVVAGLLFVNLGLREGGSTWNGPDFYQAMAGASTVAFVSLGAMFWGGFYLVGLAFLLLIPVMPIDPRFCPIEYGSVWAMVSLLIGLRLRKLAKHQAGHV
>NZ_CP042425.1|WP_149115490.1|3074798_3075578_-|ferritin-like-domain-containing-protein
MWSSAQWVAYFRENAAAHRPIPWESGTGATAAEVAEIAPSLRSWQLGETSDGRQLLVAAHRYAAAANDPDFVEAIRLFIGEEQRHGELLGRFLDLAGVGRAATTWGDSFFRAARHALPSMEVWATPVVMVEVHAMVYYNAIRRATPSPVLRAICEQILADEVPHIRFQCERLAVLHRRRLRVFRGLTTAFHEAFFLAITLAVWAGHRRALRAGGYNFGRYWKAVWGKMRAAWRAMDAKGYTWEAEAPAIRSRRRGVLEG
>NZ_CP042425.1|WP_149110483.1|3074244_3074802_+|exonuclease
METYVSTDVETDGPIPGPHSMLSFGSAAFTPDGKLVSTFEANLHTLPDAVGDPKTMAWWETQPEAWAECRRDLRDPAAAMADYVAWVKGLPGKPVFVAYPAGFDFLFVYWYLIRFAGESPFSFSALDVKTFAMAVLGCEYRAASKRNMPKRWFTDRPHTHKALDDAFGQGELFCNMLAESRRAKG
>NZ_CP042425.1|WP_149110482.1|3073580_3074228_+|DUF1080-domain-containing-protein
MRFAFCLIGFAFSGIASGADDWQPLFNGKDLTGWRANNDPDSFAVKDGVIRVQASGNKAAHLFYVGDLKKGVEKFKNFELEVTARSEPEANSGIFIHTDVTANAKGHLDKGYEVQLNSTAKEKRKTGSLYAVVDRDTSPVDETKWFTVRVRVQDKRITVAIDGKEVVDYTEPAGVVRPKDRAGRLLSADGGGIALQAHDAKSVWYFKDIRVKHLP
>NZ_CP042425.1|WP_149110481.1|3072629_3073448_+|hypothetical-protein
MSKVLKELVERLAVAPTQANRDAFLRGLVMSMIWTPIRTQKEGPPQPMTLGPDGQPALLVYADGSAALREPGVKSAGGGPGRESLERALASGAKLTVTTGHETTAPQAVVTAGEIPAVLALGRAEDPVLGVITWHPSSDDDNGFWEFEAGPVENHSVAGVVVPDAPWESIRPDELSRIRQTVQWVRGNDFAVRSHIAAEMWDWWYNEYCDPPDREEVRTQEEFRDKLSLEVIRFEPGEDGFLDYADHGLVCGYGIRVYVRPDGRFTRGPEIG
>NZ_CP042425.1|WP_149110480.1|3070160_3072458_+|hypothetical-protein
MVTDTAADAKTTQPRNLWQLPIFLLGLLALYGAYKYVPHRGATAGPATAGELADLKSALEQRSPDAAAIEPLVRKLAATNPTDTPTNFALGSGYVALADKAGGDGIEYWAAAEKAFERCDVTQLDNHGEAAKMIFRFALAKAATETGNPAEVLGAMTSPPAGEDRAEYPRLVAQTFLRMTPPNYAGAKEAFAKYLGGQNRSTPATAAKYKLELVKLHLRDKELDKAKTWLKDIGTTAPADVQAAAKVQLGRVAMAEQNWADAVAQFEAALLSGQLPTEERTTVRYQAALSLMQSGNDAAAAPYLKQVLAQPGEVAAAAAMKLAAIGSRDPAAKGSRKEAAEWLEKAVTQASATSEHVKTPELRAVFEEVIKASTSEGDFEAAHRAATAYAKIAEESADRKYRAEINAQWATALVKTNPADAKPKFMDAATEYATLADRALDPKERAELFRKGALQYQKAGESSKALELVTSVLNGKDVPSELLGRAWLDRADLLPPDQAAEIEEALKRAVSLPGSAATPARYKLAVTYVKRGQELLAGAAGSVQPDALKQQAAVTTKLGRDMLAQIADASTVPTDDQFTHEQAIFELGRLAMLDRKYPDAEARLRKQLTLYPQGVHADNARLWLASALLAKAQTDASVGPKARTEALVYLKELANSTDPFLQTWGEIWQANTLLQMGDTAATIPLCRELMAKHRGKLEELVLGKLLFHAYLSSRPADPGEAQKTLTRMEELFQALPRDAFRTDAEYSYDHWKAELPRLREALVKR
>NZ_CP042425.1|WP_149110479.1|3069566_3070010_-|hypothetical-protein
MTNLLQWDIVLEQFQHKNGGYRVKRRLLRISLVVVLIVMSGCVYLNNVPWITVQEVRNQIERELPVGTPRWQVSDWLITKGYSKSGIGEGCCDKGDGSGQRHTLSLTEFSNYRIEFPFPTYLLIWIEFDAAGRRTDRIDVREFSPSF
>NZ_CP042425.1|WP_149110478.1|3069289_3069487_+|hypothetical-protein
MAKRRRDGSYREPAALRRIRESLTEEKQLQEFRKVFGCDPSSEDQLEVFIEHLTLEMYNAGCDQR
>NZ_CP042425.1|WP_149110477.1|3067377_3069243_+|hypothetical-protein
MSRLCLVLALATVGLPATGAVDKQKNDAALKKGVEFLKQHLNETAHGTGVPALVGLAMLEGDVPKTDPAIVSITRALREGGPGETKTYNLALSVLFLDKHNDPNDVPLIQLLGARLIVGQTNFGGWGYNCFPEVPAAEQARLASALRPTGAGGLHPEAAAILRLGRAGNAASEGGDDNSNTQFGLIGTWVAQRRGVPASPAITAVDTRFLRTQSPTDHGWSYNASTSGASSTPAMTCAGLLGLAVGKANDEARKAGRKLVGEGNPKPKAKEDDDPFYNPPARNEKPKKEEEAEDDPEEDDQPKKKPLTIRDMAIERALQALGRVLKQGSGGASAGTRGGVDDLYFLWSLERVAVAYGLDTIGDVDWYEWGTKSLLATQGADGSWPGGNDGTVVNTAFAVLFLKKSNLVADLTRQINGKIKDPGNGELRGSRGGPLAIAAFGRKIDVNTDGAPDPTSPNVGKVRGLSEADRIANGLLAKQSDTKWDGKLKAVRDGKGGQNTAGLAQAIPLLPDKRMIEARAALADRLTRMTAATLKAMLADRDAELRRAACLAVAMKDEKSLTLDLIDRVTDIDDIVVRATRASLKAMFNKDLGPPTGSNDERKRIALDEWKSWYTREGPKP
>NZ_CP042425.1|WP_168219516.1|3078937_3079207_-|hypothetical-protein
MEYRWQSQVLRCLFGNPFHASTIESSWLTSTAIALAEGIYADKAFDRLPILADALQDTGCENADILTHLRGDGPHVRGCWALDLVLGKE
>NZ_CP042425.1|WP_149110485.1|3079696_3081427_+|sigma-70-family-RNA-polymerase-sigma-factor
MAGSRLSTLCRHFTAAVSDTAADAELLARFTANRDEAAFAVLVRRHGPMVWGVCRNLLPNAADADDAFQATFLALVRGAKAVRKPEALGAWLHGVAVRVAHKLRRTAARRNLREKKAAVGEAVRPVADSRWDEVLAAVHEEVNRLPDGERTAFVVCCLEGVRQPDAAAQLGWKPGTLTGRLSKAKQRLLDRLTRRGLAPAAALGALGLGATTGQAIVPTKLLDAVLPFASATATVPASVLQLSQGVLDMTITKVKFLAAAVLIAGGLATGLGANFFANADAQSAPPGGLTPPVAPGAPPAPPAPATPPVGVAPNPGYTPVAPKAAPTPQPMAGGMTGGITNGPVRRPWDYKFVDVSAMSVDELKKALAAEGDQSWELAALEHRQFPGSGVTSHLAVFKRLRVLSFGTTPDAAPGGSRGATPSNTPFPTPEPKIPPPTPVAKPVAPSPFVQTSPPGAPPIKVLKLHTISLKTANSVQMAKVLKELVAIQQFGDDVTAVIADEGSNSLLVRASDDGLKAVEKQVRQLEQAAAERINADQAKQDQMRREMEVERFKRTNREAAPETIPPAFVPATPSKP
>NZ_CP042425.1|WP_149110486.1|3081498_3082530_+|aldo/keto-reductase
MEFRQLGHSGLKVPVLSLGTGTFGGANEFFKAWGSSDVAEASRLIDICLDAGLNMFDTADIYSDGKAEEILGQAIKGRRDKLLISTKGTFRFGKDTNDVGSSRHHLTRSVEGSLKRLGTDYIDLYQLHGFDAVTPIEEVLNTFDVLVRQGKVRYVGCSNFSGWHLMKSLAVAEKYNLPRYVAHQAYYSLVGRDYEWELMPLGLDQKVGAVVWSPLGWGRLTGKVRRGQPLPKESRLNSQLSNDKGPPLADEYVYKVVDALDEVAKETGKTLPQIALNWLLQRPTVATVIVGARNEEQLKQNLGAVGWNLTPAQVAKLDAASATTLAYPYWHQRGFEERNPAPV
>NZ_CP042425.1|WP_149110487.1|3082750_3083296_+|DUF2721-domain-containing-protein
MDLDSNPFIAFSFIVAPAVLTNASSILTLSTSNRLARAVDQTRDITTELERQEVLQTLYAEGRLKELTSYQRRMVMLTRALGAFYVALSGFATTTMLALLGAILSTFVPAGVAQALAVAAVIILGVAVVSMAHGALMLALETRIAIGVLNDRAVRLGQGIAGRPGSADLPRRSYTDAETEL
>NZ_CP042425.1|WP_149110488.1|3083365_3084241_+|alpha/beta-hydrolase-fold-domain-containing-protein
MAAMMLVLALWAGKAPHAVGDSKWDKPNVTVYPAPKATANGAACVICPGGGYGFLADEHEGRDAALFLNKHGVTAFVLQYRIAQPDRPGPLLSAPLEDAQRAIRTVRFKAKDFGIDPARIGIWGFSAGGHLASTAGTHFDDKTDGDEIDRVSCRPDFLVLSYPVISTDPKVTHGGSVKNLLGDKPDAKLLEYYSNDKQVTAKTPPTFIFHTSEDTAVLPENALLFVQACKKAKVPCELHMYAKGVHGLGLGTGWKDAKDPTKWRIKPEPSVAGWPDCLIDWMAAQKLLEKK
>NZ_CP042425.1|WP_149115493.1|3084393_3085623_+|Glu/Leu/Phe/Val-dehydrogenase
MACQQLRDVAKVIDLEEGIESRLMLPKRSLVCAVPIRMDTGETRNFIGYRVQHSLTSGASKGGLRYAPQVDLGEVAALAMWMSWKCGIMNLPYGGAKGGIACDPVTMSTGEKERLTRRFTEEVLSIIGPRIDVMAPDMGTDDQTMAWIYDTYSMKVGYACPEIVTGKPVELGGCVGRREATGRGVVYCIREALSELNLTPHESTAVVQGFGNVGSVTCDELAKHGTKILAVGDRYGSIRNMTGIDVAALARYANADPKKSIVGFPGAEAIPDAELLTTPCTVLVPAAMERQITKDNAANLKCRILAEGANGPTTPEADAILEAAGVFIIPDVLCNAGGVTVSYFEWVQDIQQLMWSERQVNEKLRELMLAAFHRVRKLAKERNLPMRMAALALGVNKVALEKQRRGLFP
>NZ_CP042425.1|WP_149110489.1|3086047_3086833_+|hypothetical-protein
MFFPPSFECTGRSRGLSVPRAFLADFIHFARKMPLVAVSRRMDLGPVVAARKAVTPSPNWVLLFAKAFARVAADRPELRRAFMTFPWTHFYECDQSVAAIAVEREYAGEPMVLFALFRNPHETPLAELAGRLHEFKTKPLESLEPLHRTIRITKLPKLVRRALWVHALYQSGRIKAQNFGTFGISSVAVAGATTVGMASLLTNTLSLGPFDESGHLDVRLDFDHRVYDGVPAAKALAEVERVLRTEIVAELQTMAPPTRTE
>NZ_CP042425.1|WP_149110490.1|3086845_3087655_+|hypothetical-protein
MRRVRGRWISVSQPRRVIAELMRTCHTIPIITIETRMQLAELVAARNGIPNPPSWVAVFAKAFGIVAKRRAELRRSYMPWPWPHFYETEDSIGTVSVEREFHGEPAVFFGQFRLPDQQTLTRLQEIIDHWRTTPVEQVRDFKRLLRLMWWPRPVRRFCWWYASQVAGRHRTRQFGTFAISTTASTGATCINLISPVTATLNYGLLAEDGSLDVRLHFDHRVMDGMPAARALAEIEDVLRTTILAELREMAAPANRTGVRSVEIVVSRER
>NZ_CP042425.1|WP_168218971.1|3087709_3088861_-|TlpA-family-protein-disulfide-reductase
MRIFPHALLGLFVAAIGCTAEEKKDTAEKKAEKPKLGIGDPTPAIVSATWAKGPETKIEKGKVYVVEFWATWCGPCIKSMPHLTSLLEEYKGQGLNVIAVTTKDENGNTQEAVQEFLKKRGTRFPFPFAFCTTDATNAAFMDASGTDGIPASFVVDQDGKIAFIGHPSELDDVLPRIFSGKWQGQKSIDEIQKEKDDLDAILNRVQTAAEKAEKDNTGKGQEVVTQLVADAAAAAAADVLKAFPAYEKQYPIRATQPVFTAVKLAVSLQARKFDEAGPLSDSLIKQAVEKKDVQTLSRIRNFWLAKALNPERKSVGYAVKAADEIVKIEGEEDIAVLLGAAEAHYAAGDKDKGKQYGDKALQLAGTDKRAKDSIEKALTGFQK
>NZ_CP042425.1|WP_149110492.1|3088958_3089348_-|hypothetical-protein
MFGFPPFENKSDPIATRAVFFRRLGRNFLVMCGFIAFSLTVGTLGYHYVGGVEWVDGLLNAAMILTGMGPVDPMKTTAGKLFATFYALYSGIAFLTMIAVLVAPIYHRMLHRLHLETEDDKDGDDEKPK

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Crispr_ID: NZ_CP042425_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_5

3380749-3380860

Orphan

Consensus_repeat	Method
CGGCCGATTTCGTTTCACGTTTGGTGGAATTGCAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_5

>merge|NZ_CP042425|5|3380749-3380860|CRISPRCasFinder
CGGCCGATTTCGTTTCACGTTTGGTGGAATTGCAAGGTGAAAATCATAGGCCGCGACAATATCCCGTTGACCGCGCGGCCGATTTCGTTTCACGTCTGGTGGAATTGCAAGG

>NZ_CP042425|5|5|3380749-3380860|CRISPRCasFinder
CGGCCGATTTCGTTTCACGTTTGGTGGAATTGCAAGG	TGAAAATCATAGGCCGCGACAATATCCCGTTGACCGCG
CGGCCGATTTCGTTTCACGTCTGGTGGAATTGCAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149110745.1\|3385826_3387158_+\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|369446
NZ_CP042425.1\|WP_149110738.1\|3377871_3378216_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|163261
NZ_CP042425.1\|WP_149110736.1\|3376123_3376651_-\|DUF2721-domain-containing-protein	unknown	unknown	gnl\|CDD\|378544
NZ_CP042425.1\|WP_149110739.1\|3379126_3380722_+\|TROVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|368584
NZ_CP042425.1\|WP_149110730.1\|3370345_3371263_-\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|225201
NZ_CP042425.1\|WP_168218996.1\|3384988_3385591_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110731.1\|3371272_3372076_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234723
NZ_CP042425.1\|WP_168218997.1\|3389746_3391021_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NZ_CP042425.1\|WP_149110746.1\|3387208_3387865_-\|HAD-IB-family-phosphatase	unknown	unknown	gnl\|CDD\|226802
NZ_CP042425.1\|WP_149110734.1\|3373069_3374851_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NZ_CP042425.1\|WP_149110733.1\|3372608_3372923_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168218995.1\|3383451_3384768_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP042425.1\|WP_149110742.1\|3381833_3383345_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110748.1\|3388833_3389640_-\|TIM-barrel-protein	unknown	unknown	gnl\|CDD\|224007
NZ_CP042425.1\|WP_149110732.1\|3372176_3372584_+\|DUF393-domain-containing-protein	unknown	unknown	gnl\|CDD\|367833
NZ_CP042425.1\|WP_149110735.1\|3374961_3376116_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP042425.1\|WP_149110750.1\|3391183_3393712_-\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|320700
NZ_CP042425.1\|WP_149110741.1\|3381358_3381823_-\|alpha/beta-hydrolase	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110737.1\|3377107_3377875_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110747.1\|3387866_3388754_-\|crystallin-J1	unknown	unknown	gnl\|CDD\|377122

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149110750.1\|3391183_3393712_-\|PDZ-domain-containing-protein	gnl\|CDD\|320700	cd07341, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	1.17303e-35
NZ_CP042425.1\|WP_149110738.1\|3377871_3378216_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	1.16638e-26
NZ_CP042425.1\|WP_149110736.1\|3376123_3376651_-\|DUF2721-domain-containing-protein	gnl\|CDD\|378544	pfam11026, DUF2721, Protein of unknown function (DUF2721). This family is conserved in bacteria. The function is not known.	6.16494e-18
NZ_CP042425.1\|WP_149110739.1\|3379126_3380722_+\|TROVE-domain-containing-protein	gnl\|CDD\|368584	pfam05731, TROVE, TROVE domain. This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-binding.	3.77584e-103
NZ_CP042425.1\|WP_149110730.1\|3370345_3371263_-\|WD40-repeat-domain-containing-protein	gnl\|CDD\|225201	COG2319, COG2319, FOG: WD40 repeat [General function prediction only].	2.12172e-12
NZ_CP042425.1\|WP_149110731.1\|3371272_3372076_-\|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl\|CDD\|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	1.71116e-155
NZ_CP042425.1\|WP_168218997.1\|3389746_3391021_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	2.34725e-19
NZ_CP042425.1\|WP_149110748.1\|3388833_3389640_-\|TIM-barrel-protein	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	5.90099e-31
NZ_CP042425.1\|WP_149110734.1\|3373069_3374851_+\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	5.28817e-12
NZ_CP042425.1\|WP_149110745.1\|3385826_3387158_+\|outer-membrane-beta-barrel-protein	gnl\|CDD\|369446	pfam07642, BBP2, Putative beta-barrel porin-2, OmpL-like. bbp2. BBP2 is a family of putative porin proteins that are likely to be outer membrane beta barrel proteins porins.	1.14373e-47
NZ_CP042425.1\|WP_168218995.1\|3383451_3384768_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.76563e-51
NZ_CP042425.1\|WP_149110746.1\|3387208_3387865_-\|HAD-IB-family-phosphatase	gnl\|CDD\|226802	COG4359, COG4359, Uncharacterized conserved protein [Function unknown].	4.80385e-18
NZ_CP042425.1\|WP_149110732.1\|3372176_3372584_+\|DUF393-domain-containing-protein	gnl\|CDD\|367833	pfam04134, DUF393, Protein of unknown function, DUF393. Members of this family have two highly conserved cysteine residues near their N-terminus. The function of these proteins is unknown.	1.64809e-25
NZ_CP042425.1\|WP_149110735.1\|3374961_3376116_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.92147e-71
NZ_CP042425.1\|WP_149110747.1\|3387866_3388754_-\|crystallin-J1	gnl\|CDD\|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	3.94947e-46

>NZ_CP042425.1|WP_149110739.1|3379126_3380722_+|TROVE-domain-containing-protein
MKWFKHVSPKVTPQSEPVPGKPTVANSAGGYSFAVDDWKRLDRFLVLGSEGGSYYATERKLTVENAAAVVACAKADAAEAVRRVVAVSDAGRAAKNDYAVFALSLIAANADAVGKKAAYEAVPKVCRTGTHLFQFAAASDALRGWGRGLRQAVADWYVNKPVRDLAYQMTKYQQRDGWSHRDLLRLAHPKTDFTGRNDLFAWAVGKKPTVDEVPPDGDLAPLYALEAAKKATTEDEIVRLIRDYRLVREGVPTNFLTSAKVWEALLANMPLTAMLRNLATMTRVGLLAHGSDAVKAVVGQLTDASRLKKARVHPLSLLVALKTYESGKSARGSGEWVPLKEIVNAIDDAFYLAFQAVEPTNKRWMLALDVSGSMGGGTVCGTVGITPHVASAAMALVTAATEKDRTFVGFSDRLVPVGIDAGMRLDAAVRMIEAIPMGGTDCALPMLYAKDNKIPVDVFAVYTDSETWFGKVHPFQALKQYRDATGIPAKLIVVGMVSNGFTIADPGDAGMMDVVGFDTTAPAVMADFARG
>NZ_CP042425.1|WP_149110738.1|3377871_3378216_-|PadR-family-transcriptional-regulator
MEPISGDALRGHLETMALASLEKGEAHGFEILRRLTEAGCGALRLKEGSLYPALYRLEKAGLIASHWEDESAPRRGPRKRVYRITKQGTRQLAAGRAEWQQFVQVVGNILGAPA
>NZ_CP042425.1|WP_149110737.1|3377107_3377875_-|hypothetical-protein
MNEFMVLVERAVRPVQAGPKRKLRMREELLAHLTGIHEEELARLGDDSAARAAAVQRFGDPAALTVELQQSVSFSDRMDARMDRAFGWRPGESATRHSARQAGLIALVILPWLPFVLLVAGTGQPDDEPVPSTATLLRFFGGLLVFVPALVFALSVLYFRMRDSLHGAFGAPRSWRRVIGFGALSLLVLPVLGTAFSLISMGATSEIPEESTTARSIAGLFVGFLIVPLFLAGLAWKLGGSEIRHAEWASLDIGQ
>NZ_CP042425.1|WP_149110736.1|3376123_3376651_-|DUF2721-domain-containing-protein
MNPPLYQTVTAMIAPALFLTATASLIISTANRMGRIIDRIRKLVEVGNEIGQKPEDFDFADARLTHIGIQLDYLQIRNRRVMVAVTELYLAFGAFVGSSLTIAVDSFTGHYLAGVPTVFATAGVGLLFAASINLVFEARSALRTNHVEVEFYRELSARRREQAARQSPGADHLTA
>NZ_CP042425.1|WP_149110735.1|3374961_3376116_+|serine-hydrolase
MIRTLTLFFTLLLAAPVRADNPPSKELATALQPFVDRGNLAGAVVLVADKEKTLAVQAVGFSDVAGKVPLTTDALFWIASQSKPITATALMILVDEGKVKLDDPVAKYLPEFNNVWLFAEGDKEHVSLKRPRRAVTVRDVLSHTSGLPFSSAAETPTLDGLPLAAAVKTYAMTPLATEPGAKYQYSNAGINTAGRIMEVVSKMPYEDFLQKRLFDPLGMADTTFWPSESQVKRLAKSYKPGKGGTGLEELTVGQLRYPLGDRAHRFPMPAGGLFSTAADVGRFCQMVLNGGTLDGKRILSEDAVKEMTKRQTPPELKESYGLGWSVGGGTFGHGGAFATDMTVDVKRGLVYVYLVQHSGFPGDGGKARDAFRKAAEARFAPAGK
>NZ_CP042425.1|WP_149110734.1|3373069_3374851_+|hypothetical-protein
MNRRVWCASIATTVSWVGVAAAQAPPSATPAGSSPSADGPVYVMKTAGQPERRVKVVKSEKLPDGTYLTDVKDLASGVVYTLTNPAVLGIPVGNTVPAAPKPTPVAANLPATTGTVAPAPGTPRPIFGSFQNQPQQTVAKALTTPSVANPPAYTAGTPRPIFGAFSNQPQAQPGTSVMRTAAGEKMIPADIGSSAASSQGLPQARNRKTDPLLAGASTAPSSSPAAMTARTPFSVAAGAPPSVLGKILGDPSQDPPLPQPRVGILPPPAARPFATVVAQENLGAPPTMLPPPTEVVAKPAAPAAVAKAVPPAPVPVASAPVPVASAPVPVAAAPIPVEKAVAAEGGLAVPSIDPNAKPTAATGIFDSQPATTVQASSEERQPSVLIPPIDAAVAAAGPSRVIPPIAAAPAPEPAAIPPVATATLPPAIALPTPVESAPAIPQPAVAVAAVPTPAPAVEPAPRFVPPPVVDVPAAIVEAPAVEAPRAVATGALPADVQAMIEGLKTHRRPSYRMENATSLAESAYARHPDVLSALMQAARSDTSGVVRGHCISQLATVGYSDVTFLQLLDSWTNDSEPAVRRSAAMAKTKLTGR
>NZ_CP042425.1|WP_149110733.1|3372608_3372923_+|hypothetical-protein
MNAILDKDPGIVAVIDRLRARLGRDAFIIADHWEGDLCAIGIASPHDPRVLVYISNYGEKAERFSCELEVPPTNNEPPYRVAGEAAHLSFDELADLISNHFQRS
>NZ_CP042425.1|WP_149110732.1|3372176_3372584_+|DUF393-domain-containing-protein
MNHASADTGIVLYDGDCAFCQRSVRILKSLDWFHRLQFQSARETDKLPATTVPLDHQKLIEEMHVVPPDRNRAYAGFSAFRWMAWRLPATTLLAPFLYIPGVLWLGNRAYRWVARNRFKLMPCGDGGCQVQLKKK
>NZ_CP042425.1|WP_149110731.1|3371272_3372076_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MSSIPPPVKPVTVPEFRSAKGQRKLAVVTGYDYTAARLLDAAGVDCILVGDSLGMVMQGHPNPLPVTLPQMLYHVQCVLRGTKRALVIGDLPFLSYHESPRQAVRNAGKFLKAGAAGVKLEGGERMAEQIAACVRADIPVMGHVGLTPQSVQRFGGFKVQRNAAQIVADAKAVEQAGAFSLVIESVPPAIAEEVTKAVSIPTIGIGAGAECDGQVLVFHDLLGLFPDFRPKFVKAFAELGTAVTAGVSAYCQAVRDGTFPGPEHTFK
>NZ_CP042425.1|WP_149110730.1|3370345_3371263_-|WD40-repeat-domain-containing-protein
MLILSHVKQSVESLAFSPDGRFIAVGGTSGKVGLQIWSWATQSRMSQKTSVPVAVYGLWWLADGRLLVGRAGLGVHIYQRDPADLWVITCFHNALLTGITPTGHGWASYRPPLAHENHLFGIRLSAADVRHEEWSVPIGLTGRSKMAFALAGGRFLSVEEEYADLQPKIRVYLRSTATGEVLEQLTYPYWVIGPGTVAPDGLSFWIAYHRSIIRWQVGNPTHFADLIQNDSRQHFTALAFSPDGRHLAAAGNDQAVKFYDAETGQLAKTFTWDIGRMRSIAFSPDGTMAAAGSDTGRVVVWDVDV
>NZ_CP042425.1|WP_149110741.1|3381358_3381823_-|alpha/beta-hydrolase
MKILFLHGWNSVVGGVKPTCLKDHGHEVLNPALPHEDFDEALRIAQAEFDQNRPQVVVGSSRGGAVAMSMDSGGAKLILLCPAWRKYGAARTVKAGSVVLHSRGDDVVPFADSEELIATSGLPTSALIEVGRDHRLADAEPLAAMLAACEFGRQ
>NZ_CP042425.1|WP_149110742.1|3381833_3383345_-|hypothetical-protein
MRLPIAVLTAVTVGVLAASAQTTSGVDPIDYLAKSAAPITTVPELEAYLKPKTIDEVDKAYPLPQDPKTIQKVRADRLKQLRADTVDVYNKFGSTKAAWADKARTAMEAFCLAYTRSAVTDKGPYCQAFFKALKNLEGIDCGDPLIRYWMLQYSPRSATEESLPKYVAAVDALEKSKYTRLTFHAAYQTYAIAYQLARKADTAVTAEDLENRHQQYRTALKAMITDPRPAYWADALPLLTLEVQLHMESGKSRLGAWRDVDDRLEGMEAVPWVRAALEGRVLVLAAWDARGNGAGNTVDAEAFEIFKDRLATAQQKLEAAWQADSTLAAPATHMLDVAKGLGFEREAMETWFRRAMEADPDNLTACEAKKDWLQLKWRGKPKDALAFTYQCLRTNNYYAHLPFLAETPQLAVLPVEKQELIEEYTGRAGTWTPVQVIYEAHLARYPDDVWAHTRYAQRSGLWGKWDVADAQFKALGGKPWPGIFAKDEFTRLAQKAKDEATKK
>NZ_CP042425.1|WP_168218995.1|3383451_3384768_-|sigma-54-interacting-transcriptional-regulator
MSSPPPPPDDSPPRRERWSSLLQNSAKPLFVLYRTRRVRFVNAAWEQLTRTSAADAIGRACVRSGKIEPLFRTLAPPPEAIAGQVARVRRAVPPAKGGPPWWDVTFLPLTSADGAHGFLGVIDLVQPQPAVPAKKLPAVVADVREKHAAAFTFDLFASAAPTGERLLGQLRLAAQTGVPVWIVGEPGAGKETAARVIHHHSAHRERAFVACDGRGLQPYLIDSILFGHGGLAGSGKVGTLLLKSPAALPRDLQQRLADWLRAGPHPPRLICTSAHDAATDVKAGTLRGEFQTEFSVLELRVPPLRDRADDLPRILAALPATVSPEALAVLQVHAWPGNVRELIATVTDAADRAGGEAVGVAHLPRYLRERAMLAANPAPPAQKKWNLDDLLTAVEKRLIELALRKADGNQTEAAALLGIFRTRLGRRIEALKIADPGA
>NZ_CP042425.1|WP_168218996.1|3384988_3385591_+|hypothetical-protein
MPPTPTVRTTDLDRIVLASLKEVHNKGAELYNAGDHAGALRLYQGGLIVAKPLLDHRAKQQTEIHEGLDQVTKSTADVKLKAFRLHEVIEQVRGDLKEEAKLAAASEKPAEAAASGKVTLNGKPTAGVTVAFIPVGTTKALGTAKAGEDGTFHAATALNVGTYLVTLVGDGMPAKFTKPETTPLRAELKAGVNSLVFDAK
>NZ_CP042425.1|WP_149110745.1|3385826_3387158_+|outer-membrane-beta-barrel-protein
MITTMLLGTWLAAGQAPAPMPMPMAPKALPMAVPMAVPMTAPAAAPPAAPAPMAVGTPVAAPAPEAPTAEEPPKEDTKYFVEKLLAGSAFGQRLADNGVKINGWAGMSYTGSTTSRTNLPITFNDQANSFQLNQVWLNVTKGIDTSKKEVQFGYNIATFYGTDYRFTIPRGFLQYQVEDQRNYGFDVVYHYAEIFLPNLGGEGTTLRAGRWGTGIGYEVIDTVNTPFLTKSYNFQYNPFTHTGVQANTQINENLSMYNGAVTGSDVYIDPAARLTYVGGIKYAPKDGKGFISFNTVIGPGRYLGKENFVHFNSFNVTGSYNLTDKLTYVLDATFSYADKFPAGFGNVQDPGTSADWYGFANYFLYKVNDKLSSNFRVELFNDTKGVRTGFEGLYTEMTYGLTYTPKDWMILRPFVRYDYNSRSTPFEGDHHLVTGGIEAILRY
>NZ_CP042425.1|WP_149110746.1|3387208_3387865_-|HAD-IB-family-phosphatase
MDAAQPRRVFVTDFDGTFTRHDFYNLFLEQLYPADAPDQWAAFSADKITHFECLRNIYAHVPVGEEKLRAFVQQLYLLPEVPAAVARLKAAGWEVVVASAGSRWYIEQVLAAAGLNLPVHTNHGRIVDGRLLMELPTDSPFFHPHAGIDKAAVVRSFLDAGCEVAFAGDGITDIPPALLVPPRLRFATGFLARKLTERGEAFHSFTEWCQAAEVLLEK
>NZ_CP042425.1|WP_149110747.1|3387866_3388754_-|crystallin-J1
MARVQLALDGLSVGDALGSQFFLPKNHLLLQQPEPPIPWGRWGYTDDTEMALGIAEVLERHGRIDQDDLAATFARRFAAEMYRGYGPGAVRLLAAVSGGADWRIASRELFNGGSFGNGSAMRIAPVAAYFADDVNRVVEEARLSVEITHAHAEGIAGGIAVAVAGAFAWQHRGQKESVTLRAELFETVLRHTPEGDTRIGIAHASTVDPAESVATAVSLLGNGHRVTCQDTVPFCLWVIGRHLADYPAAIWTTIRGFGDIDTNAAIVGGVVALACGADGIPQDWLDAREDLQYDS
>NZ_CP042425.1|WP_149110748.1|3388833_3389640_-|TIM-barrel-protein
MNLCISQATTLSTPFADDITGYADGGCMAVEVWLTKLEKHLEGTTADATRQLLADRGVSLVTAAYQGGLLLSQGEQRQAAFDHYKRRLDLCQQFGIPTMLLVADFATRIDETALGRAIVSLKQAAQWAAAFGVRLGLEFRGSDAFCSCLETALLLVEQCDEPNVGVCLDAFHYYKGPSKPEDLDRLTPQNLSHVQLCDVPGVPRELMTDGDRVFPGEGDFRLTPIVEALNRIGYAGFVSLELMNPTIWQAKPSQVAELGLTAMRRAVG
>NZ_CP042425.1|WP_168218997.1|3389746_3391021_-|PQQ-binding-like-beta-propeller-repeat-protein
MNAHRNLGPWTAAVVLLLAGRSTSAADWPMWRGPTGMGRTTEKDLPLTWGGKTKQNVLWQTPLPGGETASQDHNQSSPVVVGSRVFVTVSYWPGKTDAAQFPEHHVACYSANDGKPVWDVRVPPGPWKLSDLRGGYTAPTPAADADHVYVVFGSAVIAALDHAGQEVWRKEIVPYKFDVAMAASPVLIGDTVVLQCDELDKQSRLIAYDRKTGDVKWEEKRPGVGFAHSTPVLATVGTEPQLLLAASNAVQGVDPTSGKVLWTCDAKGDTASPLLAGGLVYLDSGRGGSGLAVDPTGKGNVTKTHVKWTAKNVSEGYSSPAADDEYLYRLHKPELLTCRKLSTGEVIYSERLDGMNTSTSPILTPDGRLYLVSGGKSYVMKAGPKFEVLAANDLGDIASTSAAVADGRLFIKGKKFLTCIDGKK
>NZ_CP042425.1|WP_149110750.1|3391183_3393712_-|PDZ-domain-containing-protein
MSDFWPAAAIWTARSLLAGGAALLLTWLAVRRIGDPARRQRVLAGSMRAAVLAFGLTLLPAWLLIPVPGWQKPAETASRFEPVPDATQEAVDAEPEEFGWVPVGVPVSLPADGGVELLLPTEPSITPIPAAAVPAPALPEDSLAAVAPILLIPYWLGVSFVLLRQLVGHVGLARLRRAARPAPDDVQTLAAELAGDMRMPRVLVSDRVGAPVCFGVFRPTVLLPRVLPTLATPDQLRWVLAHELDHLQRGDPRTGVWAGLAGAVYFTLPWFWAVRQELNLAQEYLADAAAAGSREADYAAFLVDLSSRPGVPRSVRAVPSLAGVRAGQSDLYRRVTMLLQPKTERKSRWGRAWSALALSSAVTAAVAISGVRLTADEPRKGDKPEEGKKVERRDGDRKPEEGKRDGDRKLEDVKRDGDRKPATVREVEVRVIDGTRKDTADLEMAIEEAAKKGDVEGVKKLVAKLKAVAALSPAQPERGLRVEGRLADRVPEGAVVRVRAAVADDEAQKLEKAIEKLKQAAEEVKDQPEAKAAIEKSIAEYRKKIAEAKKSGELRLTEVKPRAVEGQQQWQGLPQARAMDQLKASMDEMMKTYEKQLAALGNDPKATEAMKEAMKAYRASMDQLTRQMAQVPGQFEFKAMPPMAFNLNGPVVAGNVLARKVPASGRLGVMIEAVPAVVAEQLDLPAGTGVVLLSVIPDSPAAKAGLKAHDILLDIAGKTVRVDDLTKVVTDQKADAPFEVVIVRKGKKETVKGLTLPDLKATAVKKSAGSSSSMSVSINDDQFTIASKEGKDGINLKGTVGDTESVTIVIQNGDDKKEYKGVKNVPAEYRDKVTKLLKSVSK

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Crispr_ID: NZ_CP042425_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_6

3880317-3880424

Orphan

Consensus_repeat	Method
CTGTAGACGCGGTCGGCCGCCGCCGCGGGGGTGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_6

>merge|NZ_CP042425|6|3880317-3880424|CRISPRCasFinder
CTGTAGACGCGGTCGGCCGCCGCCGCGGGGGTGCGGCGTTTTGGTTGCTCTTGCAAGGCTGTGGGGTCGGCTCTGTAGACGCGGTCGGCCGCCGCCGCGGGGGTGCGG

>NZ_CP042425|6|6|3880317-3880424|CRISPRCasFinder
CTGTAGACGCGGTCGGCCGCCGCCGCGGGGGTGCGG	CGTTTTGGTTGCTCTTGCAAGGCTGTGGGGTCGGCT
CTGTAGACGCGGTCGGCCGCCGCCGCGGGGGTGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149108794.1\|3881899_3883024_+\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP042425.1\|WP_149111063.1\|3872197_3873772_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP042425.1\|WP_149111067.1\|3875929_3878773_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111071.1\|3886031_3886172_+\|transposase	unknown	unknown	gnl\|CDD\|377551
NZ_CP042425.1\|WP_149111072.1\|3886311_3886803_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111070.1\|3885828_3886038_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111060.1\|3868722_3869580_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111062.1\|3871104_3871941_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223700
NZ_CP042425.1\|WP_149111061.1\|3870177_3871074_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238872
NZ_CP042425.1\|WP_149111068.1\|3878899_3879079_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109223.1\|3884895_3885675_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|136670
NZ_CP042425.1\|WP_149111064.1\|3873854_3874631_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|223774
NZ_CP042425.1\|WP_149111065.1\|3874688_3875117_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380362
NZ_CP042425.1\|WP_149111059.1\|3868293_3868683_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111066.1\|3875295_3875913_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP042425.1\|WP_149115412.1\|3881088_3881334_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111074.1\|3887891_3888323_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111075.1\|3888882_3889338_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219030.1\|3882962_3884897_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|365945
NZ_CP042425.1\|WP_149111073.1\|3886892_3887864_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149109223.1\|3884895_3885675_+\|ATP-binding-protein	gnl\|CDD\|136670	PRK08181, PRK08181, transposase; Validated.	1.01354e-53
NZ_CP042425.1\|WP_149111063.1\|3872197_3873772_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	5.41691e-137
NZ_CP042425.1\|WP_149111067.1\|3875929_3878773_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.16086e-102
NZ_CP042425.1\|WP_149111071.1\|3886031_3886172_+\|transposase	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.14358e-13
NZ_CP042425.1\|WP_149111059.1\|3868293_3868683_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.43012e-35
NZ_CP042425.1\|WP_149111062.1\|3871104_3871941_+\|hypothetical-protein	gnl\|CDD\|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	1.35585e-11
NZ_CP042425.1\|WP_149111061.1\|3870177_3871074_+\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238872	cd01834, SGNH_hydrolase_like_2, SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	9.93231e-46
NZ_CP042425.1\|WP_149111060.1\|3868722_3869580_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.6915e-35
NZ_CP042425.1\|WP_149111064.1\|3873854_3874631_-\|NAD(P)H-binding-protein	gnl\|CDD\|223774	COG0702, COG0702, Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	2.27904e-23
NZ_CP042425.1\|WP_149111065.1\|3874688_3875117_-\|cupin-domain-containing-protein	gnl\|CDD\|380362	cd02234, cupin_BLR7677-like, Bradyrhizobium japonicum BLR7677 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR7677, a Bradyrhizobium japonicum protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.68721e-32
NZ_CP042425.1\|WP_149108794.1\|3881899_3883024_+\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	3.50606e-38
NZ_CP042425.1\|WP_149111066.1\|3875295_3875913_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.40411e-15
NZ_CP042425.1\|WP_168219030.1\|3882962_3884897_-\|hypothetical-protein	gnl\|CDD\|365945	pfam00207, A2M, Alpha-2-macroglobulin family. This family includes the C-terminal region of the alpha-2-macroglobulin family.	8.35211e-23
NZ_CP042425.1\|WP_149111073.1\|3886892_3887864_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	3.39274e-31

>NZ_CP042425.1|WP_149111068.1|3878899_3879079_+|hypothetical-protein
MRVPLPVTDGVVEAFPQCPHKAYLRLAGVAGQASDFVVLLQAFDAEPQSGDPGRVAPPP
>NZ_CP042425.1|WP_149111067.1|3875929_3878773_+|protein-kinase
MSADPRVRSLIDRLLDSDATPEQVCASHPELLPEVRTRWQRVRRLRGDLDALFPPEGANGAADDAALPQVPGHRVECLLGRGGMGVVFRAWHHRLNRPVALKMMLAGAYAGPRERERFQREAEAVAGLRHPNVVQVHDAGDADGRPYFTMELVDGGSLAQTLTGAPLPVERAADLVGTLAAAVQVAHAAGVVHRDLKPANVLLAADGTPKVGDFGLARRLSDEAGLTDTGAALGTPSYMAPEQADGAAGAVGPPADVYSLGAILYELLTGRPPFCGVTAAATVQQLLSHDPAPPSRLNPCVPRDLETICLKCLQKSPRLRYGSAGDLADDLGRFRRGEAIAARPDGLARRWARRVRHRPVLTIAVAGVLVLAAALTGGALWVVSERAAVERAAEDDLREMARHREQSGWPEARAALGRALARLGGHGSADLRRRLDRADAELTLIARLDAARLAGSWSTGGKLAHARANDEYEAALRDAGVWLPGDSPETIAGRVAASDVSAALVNALDGWAELARDANQVEQILRVTRLADPDPAGWRNQARNPAVWSDKAALARVAATAPAADPCVPLFLTVAKRCRAAGIDPSEMLRRVYRTQPTDFWLNLWLAEDAYRGRRYAEAVRFCQAAVALRPDAAVAHNNLGLSLLGRDPRFGEAVEYFQDALRLDPEAHPVRLNLANALTGSLRHAEAIEHTRVALRVEPNSAVLHAMLARNLEGLKADDEALAEHRRAVECDDRNFDAQQGLRNFFLRRGRAEEARAVWKKALALNPPDHAAWYGYAELCLYLGREDEYRAARRDLLARFAGVTGPLVAERVSRACLLLPVEGDEGRKAAALVERVAAADHRQYAAYLAHFQFLQGLADYRHGRFDRAAAAMRGEASRALGPAPKLVLAMALHQSGQVADARQALAAAVTGHDWSASAVRDQDGWICHALRREAETMIPADPPTKK
>NZ_CP042425.1|WP_149111066.1|3875295_3875913_+|sigma-70-family-RNA-polymerase-sigma-factor
MFEEPTSAVVQRYLDELAGDTPAEPVVKALLDRAVRRLHHLCAALLHRSYPRLARPPLNLHADEMLGAVVERLLKALRQARPGTVRQFFALACQHMRWELNDLARRLDGQPPVPDVDHAQVPAPADSGSVLSPAGRRMIAAIDALPDAEREAFDLVRIQGMTQPEAAAVLGVSAMTVKRRLNSGLQLLADALADLDPHGIDPDPP
>NZ_CP042425.1|WP_149111065.1|3874688_3875117_-|cupin-domain-containing-protein
MIRIVLAVAVGVVVGAGGMSAAHRHEDGEKVKVLSVTDIKEKLDGKEATATVVEVTIEPGQSGERHRHPGPGFVYVLEGEYELGVDDQPTKLLKAGETFYEPTGCLHRVSKNPAAKGKTRLIAVVLHPRDAKDIAVPEPKKE
>NZ_CP042425.1|WP_149111064.1|3873854_3874631_-|NAD(P)H-binding-protein
MKIVVIGGSGLIGKKLIPLLRQRGHEAASASPSSGVNALTGEGLAAALAGADVVVDVTNSPSFADAAVMDFFVTSTRNLMAAEAAAGVRHHVAVSVVGADRLPDSGYLRAKVAQERLIATGRTPYTIVRATQFFEFLGAIAGSGADGDTVRLPAAPMQPLAADDVAAALADVVVGEPINGIVELAGPESLPMAEFVGRFLAATGDRRAVVGDPQARYFGTTLDARGLNPGANPRLGPTRFEDWSRRSLPHGKPLAHTV
>NZ_CP042425.1|WP_149111063.1|3872197_3873772_+|ATP-binding-cassette-domain-containing-protein
MAASIILAELAYDTPDGTPLFADVGLTFGPVRTGLVGRNGVGKTTLLRLISGELRPRSGRVSVNGRVAVLRQTVRPDPDQTIADRFGVTAALAVLRRAEQGEARDDELNDVDWALESRLAAALGRLGLDVPPETPLATLSGGQQTRAGLAAIVFAEPDFLLLDEPTNNLDRDGRAAVMDLLAGWQSGAIVVSHDRALLDAMDAIVELTTLGVTRYGGNWTAYRELKAQELAAAQRTLADAEKQVADAARGAQATAERQARRNGAGRRKGLGGGTPRIVLGLMKDRAEDATGGNARLAERLREQAAAAAAAARETVEILQPLTVKLPPTNLPAGKTVLRVEGLVAGYEPERPLIRDVTFAITGPERVAVTGPNGSGKTTLLAVLAGRLAPWSGTAEVMTPFTLLDQQVGVLDPGRSVRDNFRRLNPGADEQSCRAALAKFLFRSEAALQTVGTLSGGERLRAGLACVLGAVPPPFLILDEPTNHLDVNSIEAVEAGLRAYDGALLVVSHDETFLHGIGVTRRIEL
>NZ_CP042425.1|WP_149111062.1|3871104_3871941_+|hypothetical-protein
MTRTIAFCLTAGVLSASAIRADEVGTISEAKSDENGFFVHAVRSPYQAKATQIRVLLPDKREKGKTFPVVYVLPVEAGTEGRYGDGLKEVQKLDLHNRLGVIAVAPTFSHLPWYADHPTDREIRQETYFLKVVVPFVDKAFPVRATAEGRLLLGFSKSGWGAWTLLLRHPDQFGRAAAWDAPLMLDKPGKYGSGEVFGTADNFEGYRVSKLLEANAEKFRSGRRLILHGYANFRAEHEKAHALMDRFKIAHEYRDGPARKHDWHSGWVKETLEQLVAE
>NZ_CP042425.1|WP_149111061.1|3870177_3871074_+|SGNH/GDSL-hydrolase-family-protein
MTRIVIALAVAALAAPLHAQDVDTLTAGRVVVLGDSNTQAGGYVAFTTYYLEKLHPEKSFDILGLGLASETLSGLSENGHAGGKFPRPCLFERLGRVLDKAKPEVVFACYGINDGIYQPLDTARSAAFQKGVTTLIEQCQKAGVKRLFLVTPPIYDHAPKTGEADYDAVMAAYAKWETELKAPGVTIIDLHTAMRKARAARAEPFAKDSVHYGDDGHLLVARTILAAVGVTPPEETAATVKADPLFKLVERKRALRSAAWMKHVGYTRETTVAPQPLGTAEADAAKVQGQIDTLRRKK
>NZ_CP042425.1|WP_149111060.1|3868722_3869580_+|protein-kinase
MGIVHRDLKPDNALLDAHGTPKVTDFGLAKRSTSELTRTQDAAGTPAYMAPEQAKAMKFVGPAADVWSLGVMLYEALTGQPPRQPGERIDYANSGNACCRADGLGPVRHDHAQPVGRVEPVRRWVGHGPQEGTDQGLLEQVRRVEGGGVRMGGESVGLLRVVCDPVAVVHLPAEEPGHRPVQAEALGERDHRRRAGLEAEGVEQAADWRNGRRASASQSCLTIGGIYWWSPTTTTGASAASGRVAIRPRAGSSATPRRGRAGRTTRVPTVASATSVSACRRCRRA
>NZ_CP042425.1|WP_149111059.1|3868293_3868683_+|protein-kinase
MPDDPPTDSTQVQVGHPTVTAPGLPTIHGYDILRELGRGGMGVVYEARQTKIDRIVALKLMLSDDPLHKARFLAEGQVIAAVKHPHVVEVYDFDECNAGPFIAMEYLPGGTLSDRLKGGTAFPRAKRPR
>NZ_CP042425.1|WP_149115412.1|3881088_3881334_-|hypothetical-protein
MNCIFGIPYRRHAVIPPSWLTSTVVALANGIYADRAFDRLPVLADALEEAGCDDPEVLNHCRGDGGHALGCWVVDLVLNKT
>NZ_CP042425.1|WP_149108794.1|3881899_3883024_+|ISAs1-family-transposase
MPTKDVSIARYFTDLPDPRMDRTKKHTLGDILVIALCAVVCGADSWEEVEAFGEAKRDWLGKFLTLPNGIPSHDTFGRVFARLDPNRFGECVAGWMAAVCEVARLKHIAIDGKACRSAPRNTFSGCLHLVSAWAAENRLILGQAGVADGSHEIAAIPELLRVLDLKGALVTLDAAGCQKEIAKQIRKNGGHYLLSVKGNQPALHDAVFGVFDRACETDFAGVKHDGHEAVEDGHGRHEERYVTAIYDPPGLPPEWPDVAAVVLVGREREVKGKRTDTAHYYITSLKGTAAELGRLIRRHWAVENELHWCLDVAFREDANKTAAGHAGTNLGLVRRVAASLLKQDPGKGSIKGKRFKAALDEGYLLQVLQGFLED
>NZ_CP042425.1|WP_168219030.1|3882962_3884897_-|hypothetical-protein
MGRALRGTQELVVHTQAHGADGDDRYRRGDRQRTHPIRHRVGRRRPVAIEHGADRRFQCRPAVTRRGVQEAQVLAVRPRRQVRPQHVVRDAERGRREQFLAVPVPRERPRLADQPVDHVPVVDPVVTGTIRSRYADAKALLTLRDSGGIHFAKPIAFRDGLYRLHELLPPGLKYGCALDVLYPEDDTTSRQAHTFARVTPTDRLLKVNVTSLDRVAPGSLVRLDFQVDRQEPIDLIASVYDSSLLAIEADAAPDVRNYYYADDRIANRLDLVLLRRRLGDVRIDALVERVRASLRTSNLSVERRGEWSTLADNYQRKQLTTRDVAHLLRLAGVDVYCSKEANGSTANWYEGLPGRDAPLADLFGLDPKQKRLEIQFVGNTLLLQEVFSQHVPPASHRWHPVYGWDDGDGYLWNKPKPPAGRIVGGGIGGGGLGGGLGGFGGGFAGGIGGGGIGGIGGLGGAGAPAPPKPPTFTALALSNALPIAAAPDAEDDRPLPDLVAAAAVRRNFSDTAYWNAAVRTDATGHATVTVKLPDTLTRWQVVVTAVSPRMHVGGAKASIHTFQPIMVWPMLPRCFTAGDSGEVFASVHNRTGETQTIRVKLKADGGTILTPAEVAVTLKPRANASNPQGIPVRPATGSPHQGRL
>NZ_CP042425.1|WP_149109223.1|3884895_3885675_+|ATP-binding-protein
MSKTNETEAVTGNLKELGLPTMRRTFAAAAVAARANEQTFEQYLLGLSEAELSHRRENRIGRLLRASKLPLEKSWAALDTKRLPTKVVHQAKALLDGGFVDRRENVLVFGPPGSGKTHLLCAVAQELVRSGRKVLSTTCNLLVQELLLAKRELKLPKALKRLGGYPVLMVDDLGYVQQSREEMEVLFTLLAERYERGSVLLTSNLAFSGWEAIFKDPMTTAAAIDRLVHHSVIVELNVPSYRAEQAKSRRAKGTDETTA
>NZ_CP042425.1|WP_149111070.1|3885828_3886038_+|hypothetical-protein
MAEGPRPESRRTPGRSSDARPAGGFVPVRVVSDAAAEVVRPGGVVLRVPITADPAHVVRLVAAIRGATC
>NZ_CP042425.1|WP_149111071.1|3886031_3886172_+|transposase
MLTLGATGAIYLAVEPQDGRKGIDGLAGVVAAALGRDPASGDLFVS
>NZ_CP042425.1|WP_149111072.1|3886311_3886803_-|hypothetical-protein
MTRIRNARVLSAALPITVLILAGTAYADPVLAESLGLDVWEVGRLENDLRAAEACGDRLEAEFQSLQELMAVNDVILADVAAGRLELSAAARRKWELNRHRPTIRDHLNRHCRGRTGEEKVAHDLCRRIGQEYRAAPDFDALVRRLHAEYETAYHAPLPGVNR
>NZ_CP042425.1|WP_149111073.1|3886892_3887864_-|DUF1559-domain-containing-protein
MNRNRRAFTLIELLVVIAIIAILIGLLLPAVQKVREAASRIKCTNNLKQLGLAFHNYENTNGNFHSSVNRQINTGDPTPTQLSYMCWLLPYIEQGNVHVNLNYFSGWNNDPVNTPLGAIPIKIDICPSTSPEVRVGLYNNGGSNVFAYGDYVPVERVDATAPGAEVTFVAGSKSQGYGILSNINRSAAGATVYTEGIYTRKVTDVTDGTANTILLVEDTGRPQWYKAGKAFSNPDTNPTGGGAWIRPSASEIASFTGISYDGETVPGPCAVNCSNNQQPYSLHTGGLNLLFADGSVKFVNSTITVRTFAALVTFGGGEILADY
>NZ_CP042425.1|WP_149111074.1|3887891_3888323_-|hypothetical-protein
MRIRFFYAVAGVVALLGAGCTRTEPPAYPVEFEVQVLGKPAAGATVVLHPVGKADPKVPLPTGRVDAAGTVKLSTFAHEDGAPPGEYAVTIEWRPEVVVTVGSDKITEFAADKLKGKYGKPTAPAAPRVTVKKEPNKLPPLQL
>NZ_CP042425.1|WP_149111075.1|3888882_3889338_-|hypothetical-protein
MMTMNRMAATNMSGAPSTNMPEMMPASMPNMVMVPRCTMKMEKCTGGMKITCMCDDPTACTMMQNLCTMMAGGMCSVACMMNGMMVCCCNLTMGACKVEMTKDGCCVTCTSGDKACCDMIQGCCDCMTACMKTGCTCCLMMGGTPVCCCMC

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Crispr_ID: NZ_CP042425_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_8

3934442-3934575

Orphan

Consensus_repeat	Method
GACGGTGTCGTCGCCGTCGCCACCGT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP042425_8

>merge|NZ_CP042425|8|3934442-3934575|CRISPRCasFinder
GAATGTGTCGTCCCCGGCCCCGCCGAGCAGCACGTCGGTCCCCCGGCCGCCGACGATGGTGTCGTTGCCGTCGCCGCCGCGGAGGACATCGCTACCGTCGCCGCCGATGATGGTGTCGTTGCCCGCACCGCCGT

>NZ_CP042425|8|8|3934442-3934575|CRISPRCasFinder
GAATGTGTCGTCCCCGGCCCCGCCGA	GCAGCACGTCGGTCCCCCGGCCGCCGAC
GATGGTGTCGTTGCCGTCGCCGCCGC	GGAGGACATCGCTACCGTCGCCGCCGAT
GATGGTGTCGTTGCCCGCACCGCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_168219036.1\|3946841_3947282_+\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP042425.1\|WP_149111111.1\|3935584_3936193_+\|RNA-polymerase-subunit-sigma-70	unknown	unknown	gnl\|CDD\|254323
NZ_CP042425.1\|WP_149111101.1\|3918743_3918932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219034.1\|3932273_3932498_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225865
NZ_CP042425.1\|WP_149111102.1\|3919021_3921346_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111104.1\|3922606_3923278_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379799
NZ_CP042425.1\|WP_149111112.1\|3936189_3938667_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111114.1\|3939808_3941329_-\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|239569
NZ_CP042425.1\|WP_168219035.1\|3941411_3943394_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381326
NZ_CP042425.1\|WP_149111117.1\|3943983_3944622_+\|arylformamidase	unknown	unknown	gnl\|CDD\|132080
NZ_CP042425.1\|WP_149111100.1\|3918278_3918683_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111116.1\|3943784_3944000_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226363
NZ_CP042425.1\|WP_149111106.1\|3923864_3924917_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP042425.1\|WP_149111103.1\|3921616_3922414_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NZ_CP042425.1\|WP_149111107.1\|3925085_3929894_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271320
NZ_CP042425.1\|WP_168219520.1\|3938831_3939560_-\|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl\|CDD\|335469
NZ_CP042425.1\|WP_149111108.1\|3930406_3931954_-\|VCBS-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379232
NZ_CP042425.1\|WP_149111119.1\|3946037_3946721_+\|transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP042425.1\|WP_149111118.1\|3944721_3945342_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111105.1\|3923626_3923839_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_168219036.1\|3946841_3947282_+\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	3.48695e-10
NZ_CP042425.1\|WP_149111111.1\|3935584_3936193_+\|RNA-polymerase-subunit-sigma-70	gnl\|CDD\|254323	pfam07638, Sigma70_ECF, ECF sigma factor. These proteins are probably RNA polymerase sigma factors belonging to the extra-cytoplasmic function (ECF) subfamily and show sequence similarity to pfam04542 and pfam04545.	5.58517e-33
NZ_CP042425.1\|WP_149111108.1\|3930406_3931954_-\|VCBS-repeat-containing-protein	gnl\|CDD\|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	1.86856e-06
NZ_CP042425.1\|WP_149111112.1\|3936189_3938667_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.4612e-101
NZ_CP042425.1\|WP_149111102.1\|3919021_3921346_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.63087e-96
NZ_CP042425.1\|WP_149111104.1\|3922606_3923278_+\|hypothetical-protein	gnl\|CDD\|379799	pfam16227, DUF4886, Domain of unknown function (DUF4886). This domain is mainly found in uncharacterized proteins around 290 residues in length and is mainly found in various Bacteroides species. It has a curved central beta sheet flanked by helices. Distant homolog analysis showed it has a similarity with GDSL-like Lipase/Acylhydrose family. The function of this domain is still unknown.	9.52896e-11
NZ_CP042425.1\|WP_168219035.1\|3941411_3943394_+\|hypothetical-protein	gnl\|CDD\|381326	cd19100, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	8.06211e-19
NZ_CP042425.1\|WP_149111114.1\|3939808_3941329_-\|RNA-directed-DNA-polymerase	gnl\|CDD\|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	5.65653e-84
NZ_CP042425.1\|WP_149111117.1\|3943983_3944622_+\|arylformamidase	gnl\|CDD\|132080	TIGR03035, trp_arylform, arylformamidase. One of several pathways of tryptophan degradation is as follows: tryptophan 2,3-dioxygenase (1.13.11.11) uses 02 to convert Trp to L-formylkynurenine. Arylformamidase (3.5.1.9) hydrolyzes the product to L-kynurenine and formate. Kynureninase (3.7.1.3) hydrolyzes L-kynurenine to anthranilate plus alanine. Members of the seed alignment for this model are bacterial predicted metal-dependent hydrolases. All are supported as arylformamidase (3.5.1.9) by an operon structure in which kynureninase and/or tryptophan 2,3-dioxygenase genes are adjacent. The members from Bacillus cereus, Pseudomonas aeruginosa and Ralstonia metallidurans were characterized. An example from Pseudomonas fluorescens is given the gene symbol qbsH instead of kynB because of its role in quinolobactin biosynthesis, which begins with tryptophan. All members of this family should be arylformamidase (3.5.1.9). [Energy metabolism, Amino acids and amines].	8.81375e-58
NZ_CP042425.1\|WP_149111116.1\|3943784_3944000_+\|hypothetical-protein	gnl\|CDD\|226363	COG3844, COG3844, Kynureninase [Amino acid transport and metabolism].	0.00204537
NZ_CP042425.1\|WP_149111106.1\|3923864_3924917_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	4.15268e-51
NZ_CP042425.1\|WP_149111103.1\|3921616_3922414_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	6.66502e-10
NZ_CP042425.1\|WP_168219520.1\|3938831_3939560_-\|formylglycine-generating-enzyme-family-protein	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	9.77166e-32
NZ_CP042425.1\|WP_149111107.1\|3925085_3929894_+\|hypothetical-protein	gnl\|CDD\|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	2.74691e-17
NZ_CP042425.1\|WP_149111119.1\|3946037_3946721_+\|transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	0.00382052
NZ_CP042425.1\|WP_168219034.1\|3932273_3932498_+\|hypothetical-protein	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.92831e-06
NZ_CP042425.1\|WP_149111105.1\|3923626_3923839_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.15324e-09

>NZ_CP042425.1|WP_168219034.1|3932273_3932498_+|hypothetical-protein
MPLGTAHLVRAALRSVAGKDRRAVDADLGSIYQAAMAREAGMAMSKSAEVWGGQSPTIVKWRRVEWADVVAMFE
>NZ_CP042425.1|WP_149111108.1|3930406_3931954_-|VCBS-repeat-containing-protein
MQPATVTYQFSGTVTSITDTSTNHAVPVSIQDNVSTYVGTFSFNNSATGQVSGGNAFYRGTALELTATVTIDNTYTYTLNTPSSSDEIDILGNSFEFFKRGPTVTAGFSPNPPFSHFEFHGQTQTNVLASAIVTAGSNPSSGVSDQQTAGAPYYFIGASNLTVANVSPPTVPPTSPPAVPPTVPPTAAAALLGTPQFAVGADAGAGTATLYNPDGTVRFTVSPFGTSFTGGVRTAAADFNGDGVADLVAGTGPGGPTQVQILDGKDQHVLATTAPFESAFTGGVYAAAGDFNGDGVPDLVVTPDQGGGPIAAVYDGAALAKGTATELTRFFGIDDPNFRGGARATVADLTGDGIDDLIVAAGFGGGPRVAGFDGTSLTGTPKKLFGDFFAFEQALRNGIFVTAGDVNGDGYADLIAGGGPGGGPRVLAFDGKSLLTNQYVTLANFFGGNVDSRGGIRLAVKDLDGDAKADLVVGAGAGAGSHVTAYLGKNISAAGTPPPAFEFDADQSQGGVYVG
>NZ_CP042425.1|WP_149111107.1|3925085_3929894_+|hypothetical-protein
MPRTFSARSAAKRLRTRRPLAVEALEGRDVPATFTWTPTAPGTYSWNDAANWGGAGFPNAIDDVANLTAALVGNQHVNLNVPITVGTLNIGSTTATGAFTVVGSGGSLTFNVATGSAALTDTNSGGDAVLAPITVSDPLTISGNGGLPLALGVTLAGSGTITTAGTIALASGLATAAPFPLNGSGTITSDPSLFVESFYDSALYQFNARTGDLLAALLAPNSNTGLQLPAGLTTGPDGNLYLSSQNNDTILKFDRTTNQLSTFLDSTTLNNIAAMPSSGGNAHFAPAGLRFGPDGKLYVSLNGGFTSAQGAVIRFDVNSTGGVLTAPGTYTLVAGPAGVVQPSGLTFGVAAGDTGNLYFSSSATGSVVKVTGATGATPTTSQLIAPPNNGGLEFPTGLAFGPDGKLYVADLGAFTGAGKVVRFNADGTAPQTFVASGTGANPGDLAGQFPSDLLFDAQGNLITANLGPNGPTTGHNNDFAGSVYQYDSSGGFVQALVASSDFPQTGPAASFSGIIPSQLSLAAAAAFTIGSNLNPAGAATGVFTTPAVTFTGGGGLSVTLNGTSPGGGYDQLAATGPVALNGATLTVATPFAAPPGSQFTIVSAPALSGTFAGLPEGATVVVGTQQFTISYVGGTGHSVVLTRVAATAPTITGPTTATFFTGAAPSFTVTATGSPAPTFSVAGGLPPGLSLNATTGAVTGTPTATGTFTPSITATNASGSDTKAFTFTVQAGIAPAITSAAGAMFTAGTGGTFTVTATGTPAPTLAETAPLPSGVTFDPVTGVLTVAPTALAGSSVLTFTATNGVGTPASQTFALTIGNVPTFTSPNATAFATGTANSFAVVTGGSPTPTLSETGALPTGVTFDAATGTLSGTPAAATAGTYPVTFSATNLFGTTTQSFTLTVQAAAAPVITSPAASAFKVGQANTFAVTATGTPTPTLTLSGTLPTGVTFNASTGVLSGTPTAAAAGTFPLTFTATSSSGAVSQNFTLTVGSVPAFTSATTVSFATGTSGAFNVTATGAPSPTLSVAGTLPAGVTFNAATGQLSVAGTTAAGTYPLTFTAANAIGTATQNFTLTVRPGSAPAITSANTALFGVGATGSFSVTATGTPTPTLAVSGALPTGVTFNASTGVLSGTPAAGTAGTYPLTITATNGVGTGATQGFTLTVQSGATGTVPAFTSAAAATFAVGTAGSFAVTATGTPTPTLSVAGALPAGLTFNAATGLLTGTPAAGAAGVYQLTFTATNSVSTASQTVTVTVTGTPVALPGRLAVSGPTDGSVTVFDPATGGQYPAGTAVVGNPFAGLGVQVRTAVADVDGDGTPDTIYVTGPGVAVQFAVVNGKDNTLLVAATMPYEATFTGGGFVSAADLDGDGRAEIVVTPDQGGGPRVTIFGRPTTGTTATVKANFLGIDDPTFRGGARSAIGDINADGTPDLAVAAGFLGGPRVSLLDGKTLFGTPTTLVGDFFAFPGSDAVTLRNGAYVAVGDVDGDGFADLIFGGGPGGGPRVYTLSGKLVSAGNLDAAYANPVTNFFVAGNTSARGGVRVGVVDADGDGRADIAAGSGSGLPGSVRVYFGKNVTSPAEPIAFQDLNVFGSTALADGVYVG
>NZ_CP042425.1|WP_149111106.1|3923864_3924917_-|DUF1559-domain-containing-protein
MTPTPRSTSTRSGFTLIELLVVIAIIAILIGLLLPAVQKVREAAARLKCANNLKQIGLALHNYEGTNGTLPPVFPAVVKAPYVGVVPPYFYSWSVLAQLNPFLEQTAIFNRMNLDQPMYLYPSLQVSTDNQFAVQQMIPIFLCPSDSMTAGVGGYGVSQFGSSNYAACTGSGATAGGAPYGSPWDSDGVFRAKIKGRFADITDGLSGTTAFSESTLGDGATTYGPTPPGPTRKWYANVSPPLTPAACGTPSSWNYQQPRGFQWVAGEVRCVSYNHFYPPNSPQYDCVTNVTTAGEQQYTSVGFKAARSYHTGGVNVLMADGSGRFVRDAVDPTTWTAVGTRGGGETGGDY
>NZ_CP042425.1|WP_149111105.1|3923626_3923839_-|helix-turn-helix-domain-containing-protein
MPTTSLDTIRCSSLLAALAAPERLRIVRFLAAGPQNVSTIAKNLCIPNNNLSHHLATLTNANFLRREHRG
>NZ_CP042425.1|WP_149111104.1|3922606_3923278_+|hypothetical-protein
MAKKSRGHGPTKVLFIGNSFTARNDLPGLIARLAGALGRQLEHRLIHAGGASLRAHWNAGRATEAIRDGGYDAVVLQEQSTLPAKNASRMHENVRLFDGAIRAAGARTVLYMTWARQNAPDSQQAITDAYAAIGKELGATVAPAGVAWQRFLRDNDGPALHDRDQSHPTVAGSYLAACVILAALFQESPVGAEVDVPGLSAGERAALQAAAGQAWAEPASEGS
>NZ_CP042425.1|WP_149111103.1|3921616_3922414_+|helix-turn-helix-transcriptional-regulator
MSKSQRVTAADEVAILRLMNECRELGDDAMAWQQRLISGLQKLTGGMVAAVGPTPPLRGELGVLQEWVGQQLGGGWPSESLRRKWEALAADPMAMQAHPAVSAFWAMPEPSLSLTRREIVPDHVWDRSPFVNDLLRADGMDEGLVSRADVPVIGGGYVLTVVRAKGEQAFSRRAGAVVAALLRELEPHLGRGLFLTSQPNLHGLSPRLRQVLGCLLDGDSEKEAALRCRLHPTTVHEYVKHLYRHFGVSSRAELLAYFLRRYPRR
>NZ_CP042425.1|WP_149111102.1|3919021_3921346_-|protein-kinase
MDTPTQPSESSEPPAVDLLPLPSRLGDYELTAALGAGGMGVVYRARHRSLQSTAAVKVLNPAIAHHTTARQRFLQEARLTAGLRHDGVVRVVHVGEDGPVLFLVMELLEGESLTDRLKRGPAFTTDETVRIGREVASALAEAHRQNLVHRDIKPGNIFLQHIPGRPPRVKLLDFGIARRQDADQSFTSVHALIGTPHYMAPEQVDDSRVGSPADVFSLGCVLYELVSGRNPFRGRSQAASLRLIAEYDPPPLNELFPILPDAFSTVVRDCLFKDPLRRPTAEDVERRLLQVEPEPDSRTALRTVSAAADTTETQKYRPNAKPTARRWVGAFALLIALGTLGCLGLWLDSRPPKPKADDANPVADRPLPVADKSQSVLSGWRLEQPPPLDEWLRGRRIRTVRQDGGAEFRSLLAALAAVRSGEAIEILDAGPYTDFAPLPDGSVGLSVPPDVTDIGIFSRTGASLRTTKYQVNKNIPPKNGRVCYAGATIAAGAGLRLHGLTFQADPPPQNTADASAWRLSIGGPCVVEDCLWLRAAHPRPEQYLVILAFDFRNSAAMPLTVRRCWVEGTVNTHVTNPGVRTEARIERCVFTDASQNLWLQLGHARWAFLENIFQADDCCVALGTTRFAPAKGQPEVLFGRNTFLSTARSPVRVERYEKGELAKVSVALFDNAFSGPGEPIHFAASQDARESRSWASQENWSTDHSGAAWLNFLEGRIQFVSQDPLAPDFARIENSPPGTGGAGLRGPGAVPSGPLSDALEWLAYLQARRGMVSP
>NZ_CP042425.1|WP_149111101.1|3918743_3918932_-|hypothetical-protein
MSPRRARYRAPPKDAVPAGVIPLSKDAEKDKGREANADAIREHPWAVIGITPGGTYGMVKQK
>NZ_CP042425.1|WP_149111100.1|3918278_3918683_-|hypothetical-protein
MNLSRAVYDPVLSELRVHAQLKGERQLYRRAIAEYLVGRDDFFAREAKYSLHPIRRDREDCLACGDVDGLDAVLLRELHFAGGSPAVARRRERGGHGPTTGPFTSSKPAGRVAPVPNSPLTESAFARRLVRETA
>NZ_CP042425.1|WP_149111111.1|3935584_3936193_+|RNA-polymerase-subunit-sigma-70
MSSEESVTHWLTQLRDGDGEAAQQLWERYFRRLVGLARVRLQSHPRRAADEEDVALSVFCNLCDGATRGRFPRLDDRDDLWRLLVTLTERKAINLARDERRLKRGGGAVLTGDALTRPGESTAGGFDQVPGREPTPEFAAEMAEEYQRLLTRLDDPGLRSIAVWRMEGESVGEIAARLGCAVTTVERRLRLIRQLWESEGGE
>NZ_CP042425.1|WP_149111112.1|3936189_3938667_+|protein-kinase
MNGPAPDTRPDLPPELARQVDQICCRFEAEWKAVRRGDPPPRLETFLAGGPVPARPVLLRELLLVEVHHRRSVGDEPRVNEYGDRFPDLDTGWLADHLGAPDTRSLPTVAPVQLPAFLDAIRDNGILDPSQTVTAVEEAGHARQVTDLADRLVNRGWLTAFQAQRLLAGRPHELVLGEYVLLEPLGTGGMGLVFKARHRIMNRVVAVKRIRPEAADDPTALRRFRAEIQAAAHLSHPNVVVVHDAQEASGELFLVMELCEGVTLHDLVKQRGPLPPAEACEYARQACLGLQHAFERGLVHRDLKPRNLIRCGKTLKILDFGLARLRQGPAAGSSTTEGTIVGTADYMAPEQADGRADVRSDLYSLGCTLYFLLAGRPPFPGGEILDKCVRHRIEEPESLARLRPDVPRRVREIVSRLMAKDPADRFQTPAEASAELAAVSHRDIPVISPLLDSAPVLDAPPTRPARKRRTPVRFGILLAVVAIGLTSYLVIRSGPLREGPSPAQPPASPLAWKKSKTLSLPIEHAGAYGLAFSSDGRLLAGACGNHETAGPTPAGRLCLWEVAEGRLVLDRELPAGPGACVAFSPDGQRLAWATGYWGHEVPGKLTLWDVAGRADICDVEAHAQGVCALAFQPRSDLLVTSGYEGKVFLWDARSGQPLGELTDARIAVFALAFTLDGKYLVVGADDGSVNVWELATRTRVQTLSAATGKPVRGLAYLSDGETLLAVTKQGEAPPANLLAWRRGDALPTVSLGDTNAYSLALSPDRATALVGCRDNAARLFQGQTRRALQTLTADQTFYSLAFSPTGQLLATSAGLDRPVQLWEPD
>NZ_CP042425.1|WP_168219520.1|3938831_3939560_-|formylglycine-generating-enzyme-family-protein
MVWIPPGRCMIGPDRVPAEMTGFSLARHPVTNTQFARFLAATGYTPPADGDAAVGTDGYANGAFLEHWIGRTPPKELLDDPVVYVSYRDALAYCAWAGLSVPGEFQWEKAARGPDGRTYPWGDAKPARRGVAHFGSRETVAVGQYTRSRSPYGCEQMAGNVSTWCQPGDADRPGERPPPRPTVALLHVGQPLHAAVRGGAFKRAGPETLRAFHRRRLSVARRNDWVGIRPSFPLPVRPANAD
>NZ_CP042425.1|WP_149111114.1|3939808_3941329_-|RNA-directed-DNA-polymerase
MTDTPTWLLHALPANAVVDEKLNATLSALAAALADNRDKPLVTAGLLTEIQGHLAHAQPFAAYEAAVNGIAGQVWQLFEAVHQRQNRPAKLAFLNLVVRHLTPGALAQLCRRWAKDADPAIRRAVGRVIETGAIHEVALPATKDGAWSPAGWRKGTVEVDLSRHKVGTAVQEANSVPPLANLRQLRELLGIRSAKQLGYFLLASDKDDGPYTRFTVPKRGGGERVICAPKPQLKWVQRRIHERILSGVPLADAAHGFVPGRSIVSNAAAHVGAAVVVKFDLKDFFPTIHSYRMIGLFARMGYSVGTAKIATADESASVAPVLARLCSYTPDPRAWGKAHAPQGAPTSPAVSNLICRHLDARLGGLARKLGGVYTRYADDLTFSFAATGIDLGRFRWWVDQVCQQEGFVMNADKFRVIRRSQRQLVTGLVVNDGVRPTREQRRAFRAVLHNCRRNGVVTEARGDPRFSQYLRGFASYLHMVRSTEGADLVRQVAELLDPPGGGEDKP
>NZ_CP042425.1|WP_168219035.1|3941411_3943394_+|hypothetical-protein
MRVPDDHPLNVTRAFRTAGAALAAVEAAREHGGAEVLDGLFELAVAETNAAVVVATLRALAERDTPLSRVAVRRAAGSRFALARQFAIHAMDRLDDRELDSAVVKLLTTDPSWVNRRAALTALAAVGRERRWEILRTADDPHWRVRHALGRVLTAWGASETDQQEINCRLAIEQFEEGINRTRRDALLAYLTYRWTGREPGDGTAFGAPDPFAVCPFWDWDAAVLAVRLKRMTAAERAAHVNAMPFLAGHEDGRVWKSAVSAIREHGESHHYRAVLALRADPRNGAEPAIERLLDGLDEERKHELTTGPFGRRSVGEREPLEAIAGSPFQRAAALTPTTAAGIVAEPTSETSWHVIEAAGRLAKVPIWEVEPLNPWTPPTVAKPSLPPLVAPLGAGVATTLVGPDRIAVSRVGVSGHYLLPVEGFVEAAAAGVNWFFWEPNYATLTAFSSRLSASDRRPFHFVAGTFEADGRRIRADVERALRELRVERLGIFFLFWVQSWDRLTDDVRDTSAALRAEGKIAAVGLSSHRRPLLVRAMADGWDVVMARHSAAHRGAETELFPAVPPGTTLITFNNLCYGRLLEPTHGLTPPTAADCYRYTLSFPQVAACWSAPATVEQLRDNLAALREPELDPGRRDDLRAFGAKLYQHEKVFERLVRML
>NZ_CP042425.1|WP_149111116.1|3943784_3944000_+|hypothetical-protein
MTPGKLGTASGSCPHARQGVAAGTVTFTYPGAAKLSRALRLRGVVPDFRPPDMILADAAHHELPDADAPVT
>NZ_CP042425.1|WP_149111117.1|3943983_3944622_+|arylformamidase
MPPSPDRRVLDISRPVGADTAVWPGDVPFTFDLAGRKAAGASANVGAISGSVHTATHCDAPFHFDDAGETVDRLRPELFLGPAWVVDVRGASAWQPRVEALGFSATPRVLFRTGGWPDTARFPAAIPVMEPTLPGWLAARGVFLIGVDVPSVDALDSEALDNHHALGRAGILIVEGLWLDDVPPGRYEFAGLPLKLVGADASPLRAVLVSPA
>NZ_CP042425.1|WP_149111118.1|3944721_3945342_+|hypothetical-protein
MIRLYIIRAVLIAAVASTCYWLGGECSLGLAILIWAGVTTGACALGAALLRTSRVGEITWRNRAAGYLIPWGWRLSRGRLWVAAVFSWVTWMAVGGAAFAMRPGAMTEPSTTGVRAALFAAWVIDAAALVYVLGTIWQATPGSRVRSLWKLVTVITAVLGASVGLYVTGRPTEALMFGGGPPLAVGGGMGLFVLTVLIFGRNTRWN
>NZ_CP042425.1|WP_149111119.1|3946037_3946721_+|transposase
MYVLITGIGWEFVPPGFPCGKAIKTRPDRWLAIDAFRTAWQPLADRYQDLHGINWDQVLIDGSKRPSKRGTLTGPNPADRTKSGTAIHLATGGRGLPLGAVVAAANVNDGMQTRAVVDDFVIRPRRTGRTPTRPPGPTPRSRGRRVRERAGPGAGRGGRLPHDRPAAGPRRPRAGRCGPGSREGTRCSPRLAASAAGSTGTASDTSGGFNLPPSLIFLRHQANGFFR
>NZ_CP042425.1|WP_168219036.1|3946841_3947282_+|GatB/YqeY-domain-containing-protein
MSLHDELKARVIAAVRGGDGLTRDTLRTILGEAQTEAVRRTGEVTDEIVLGVVRKTVAGLKETIPLAKQAGRDTAPREVELALLESLLPKAWDREAIAAALAPLRDELRAAKNDGQAMGVAMKALKARGATTGPDDVKAVVAAVRA

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Crispr_ID: NZ_CP042425_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_7

3933785-3933952

Orphan

Consensus_repeat	Method
GACGGTGTCGTCGCCGTCGCCACCGT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP042425_7

>merge|NZ_CP042425|7|3933785-3933952|CRISPRCasFinder
GACGGTATCGCTGCCGTCGCCCGGGTTCCACGTGGTCGCGTCGTCCCCTGCGCCGAGGAAGATCACGTCATTGCCCTGTCGCCCGTCGACGGTGTCGTCGCCGTCGCCACCGTACAGCACGTCGGCACCCTGACTGCCCTGGACGGTGTCGTCGCCGTCGCCGCCGTC

>NZ_CP042425|7|7|3933785-3933952|CRISPRCasFinder
GACGGTATCGCTGCCGTCGCCCGGGT	TCCACGTGGTCGCGTCGTCCCCTGCGCCGAGGAAGATCACGTCATTGCCCTGTCGCCCGTC
GACGGTGTCGTCGCCGTCGCCACCGT	ACAGCACGTCGGCACCCTGACTGCCCTG
GACGGTGTCGTCGCCGTCGCCGCCGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_168219036.1\|3946841_3947282_+\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP042425.1\|WP_149111111.1\|3935584_3936193_+\|RNA-polymerase-subunit-sigma-70	unknown	unknown	gnl\|CDD\|254323
NZ_CP042425.1\|WP_149111101.1\|3918743_3918932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219034.1\|3932273_3932498_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225865
NZ_CP042425.1\|WP_149111102.1\|3919021_3921346_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111104.1\|3922606_3923278_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379799
NZ_CP042425.1\|WP_149111112.1\|3936189_3938667_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149111114.1\|3939808_3941329_-\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|239569
NZ_CP042425.1\|WP_168219035.1\|3941411_3943394_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381326
NZ_CP042425.1\|WP_149111117.1\|3943983_3944622_+\|arylformamidase	unknown	unknown	gnl\|CDD\|132080
NZ_CP042425.1\|WP_149111100.1\|3918278_3918683_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111116.1\|3943784_3944000_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226363
NZ_CP042425.1\|WP_149111106.1\|3923864_3924917_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP042425.1\|WP_149111103.1\|3921616_3922414_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NZ_CP042425.1\|WP_149111107.1\|3925085_3929894_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271320
NZ_CP042425.1\|WP_168219520.1\|3938831_3939560_-\|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl\|CDD\|335469
NZ_CP042425.1\|WP_149111108.1\|3930406_3931954_-\|VCBS-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379232
NZ_CP042425.1\|WP_149111119.1\|3946037_3946721_+\|transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP042425.1\|WP_149111118.1\|3944721_3945342_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111105.1\|3923626_3923839_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_168219036.1\|3946841_3947282_+\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	3.48695e-10
NZ_CP042425.1\|WP_149111111.1\|3935584_3936193_+\|RNA-polymerase-subunit-sigma-70	gnl\|CDD\|254323	pfam07638, Sigma70_ECF, ECF sigma factor. These proteins are probably RNA polymerase sigma factors belonging to the extra-cytoplasmic function (ECF) subfamily and show sequence similarity to pfam04542 and pfam04545.	5.58517e-33
NZ_CP042425.1\|WP_149111108.1\|3930406_3931954_-\|VCBS-repeat-containing-protein	gnl\|CDD\|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	1.86856e-06
NZ_CP042425.1\|WP_149111112.1\|3936189_3938667_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.4612e-101
NZ_CP042425.1\|WP_149111102.1\|3919021_3921346_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.63087e-96
NZ_CP042425.1\|WP_149111104.1\|3922606_3923278_+\|hypothetical-protein	gnl\|CDD\|379799	pfam16227, DUF4886, Domain of unknown function (DUF4886). This domain is mainly found in uncharacterized proteins around 290 residues in length and is mainly found in various Bacteroides species. It has a curved central beta sheet flanked by helices. Distant homolog analysis showed it has a similarity with GDSL-like Lipase/Acylhydrose family. The function of this domain is still unknown.	9.52896e-11
NZ_CP042425.1\|WP_168219035.1\|3941411_3943394_+\|hypothetical-protein	gnl\|CDD\|381326	cd19100, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	8.06211e-19
NZ_CP042425.1\|WP_149111114.1\|3939808_3941329_-\|RNA-directed-DNA-polymerase	gnl\|CDD\|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	5.65653e-84
NZ_CP042425.1\|WP_149111117.1\|3943983_3944622_+\|arylformamidase	gnl\|CDD\|132080	TIGR03035, trp_arylform, arylformamidase. One of several pathways of tryptophan degradation is as follows: tryptophan 2,3-dioxygenase (1.13.11.11) uses 02 to convert Trp to L-formylkynurenine. Arylformamidase (3.5.1.9) hydrolyzes the product to L-kynurenine and formate. Kynureninase (3.7.1.3) hydrolyzes L-kynurenine to anthranilate plus alanine. Members of the seed alignment for this model are bacterial predicted metal-dependent hydrolases. All are supported as arylformamidase (3.5.1.9) by an operon structure in which kynureninase and/or tryptophan 2,3-dioxygenase genes are adjacent. The members from Bacillus cereus, Pseudomonas aeruginosa and Ralstonia metallidurans were characterized. An example from Pseudomonas fluorescens is given the gene symbol qbsH instead of kynB because of its role in quinolobactin biosynthesis, which begins with tryptophan. All members of this family should be arylformamidase (3.5.1.9). [Energy metabolism, Amino acids and amines].	8.81375e-58
NZ_CP042425.1\|WP_149111116.1\|3943784_3944000_+\|hypothetical-protein	gnl\|CDD\|226363	COG3844, COG3844, Kynureninase [Amino acid transport and metabolism].	0.00204537
NZ_CP042425.1\|WP_149111106.1\|3923864_3924917_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	4.15268e-51
NZ_CP042425.1\|WP_149111103.1\|3921616_3922414_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	6.66502e-10
NZ_CP042425.1\|WP_168219520.1\|3938831_3939560_-\|formylglycine-generating-enzyme-family-protein	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	9.77166e-32
NZ_CP042425.1\|WP_149111107.1\|3925085_3929894_+\|hypothetical-protein	gnl\|CDD\|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	2.74691e-17
NZ_CP042425.1\|WP_149111119.1\|3946037_3946721_+\|transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	0.00382052
NZ_CP042425.1\|WP_168219034.1\|3932273_3932498_+\|hypothetical-protein	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.92831e-06
NZ_CP042425.1\|WP_149111105.1\|3923626_3923839_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.15324e-09

>NZ_CP042425.1|WP_168219034.1|3932273_3932498_+|hypothetical-protein
MPLGTAHLVRAALRSVAGKDRRAVDADLGSIYQAAMAREAGMAMSKSAEVWGGQSPTIVKWRRVEWADVVAMFE
>NZ_CP042425.1|WP_149111108.1|3930406_3931954_-|VCBS-repeat-containing-protein
MQPATVTYQFSGTVTSITDTSTNHAVPVSIQDNVSTYVGTFSFNNSATGQVSGGNAFYRGTALELTATVTIDNTYTYTLNTPSSSDEIDILGNSFEFFKRGPTVTAGFSPNPPFSHFEFHGQTQTNVLASAIVTAGSNPSSGVSDQQTAGAPYYFIGASNLTVANVSPPTVPPTSPPAVPPTVPPTAAAALLGTPQFAVGADAGAGTATLYNPDGTVRFTVSPFGTSFTGGVRTAAADFNGDGVADLVAGTGPGGPTQVQILDGKDQHVLATTAPFESAFTGGVYAAAGDFNGDGVPDLVVTPDQGGGPIAAVYDGAALAKGTATELTRFFGIDDPNFRGGARATVADLTGDGIDDLIVAAGFGGGPRVAGFDGTSLTGTPKKLFGDFFAFEQALRNGIFVTAGDVNGDGYADLIAGGGPGGGPRVLAFDGKSLLTNQYVTLANFFGGNVDSRGGIRLAVKDLDGDAKADLVVGAGAGAGSHVTAYLGKNISAAGTPPPAFEFDADQSQGGVYVG
>NZ_CP042425.1|WP_149111107.1|3925085_3929894_+|hypothetical-protein
MPRTFSARSAAKRLRTRRPLAVEALEGRDVPATFTWTPTAPGTYSWNDAANWGGAGFPNAIDDVANLTAALVGNQHVNLNVPITVGTLNIGSTTATGAFTVVGSGGSLTFNVATGSAALTDTNSGGDAVLAPITVSDPLTISGNGGLPLALGVTLAGSGTITTAGTIALASGLATAAPFPLNGSGTITSDPSLFVESFYDSALYQFNARTGDLLAALLAPNSNTGLQLPAGLTTGPDGNLYLSSQNNDTILKFDRTTNQLSTFLDSTTLNNIAAMPSSGGNAHFAPAGLRFGPDGKLYVSLNGGFTSAQGAVIRFDVNSTGGVLTAPGTYTLVAGPAGVVQPSGLTFGVAAGDTGNLYFSSSATGSVVKVTGATGATPTTSQLIAPPNNGGLEFPTGLAFGPDGKLYVADLGAFTGAGKVVRFNADGTAPQTFVASGTGANPGDLAGQFPSDLLFDAQGNLITANLGPNGPTTGHNNDFAGSVYQYDSSGGFVQALVASSDFPQTGPAASFSGIIPSQLSLAAAAAFTIGSNLNPAGAATGVFTTPAVTFTGGGGLSVTLNGTSPGGGYDQLAATGPVALNGATLTVATPFAAPPGSQFTIVSAPALSGTFAGLPEGATVVVGTQQFTISYVGGTGHSVVLTRVAATAPTITGPTTATFFTGAAPSFTVTATGSPAPTFSVAGGLPPGLSLNATTGAVTGTPTATGTFTPSITATNASGSDTKAFTFTVQAGIAPAITSAAGAMFTAGTGGTFTVTATGTPAPTLAETAPLPSGVTFDPVTGVLTVAPTALAGSSVLTFTATNGVGTPASQTFALTIGNVPTFTSPNATAFATGTANSFAVVTGGSPTPTLSETGALPTGVTFDAATGTLSGTPAAATAGTYPVTFSATNLFGTTTQSFTLTVQAAAAPVITSPAASAFKVGQANTFAVTATGTPTPTLTLSGTLPTGVTFNASTGVLSGTPTAAAAGTFPLTFTATSSSGAVSQNFTLTVGSVPAFTSATTVSFATGTSGAFNVTATGAPSPTLSVAGTLPAGVTFNAATGQLSVAGTTAAGTYPLTFTAANAIGTATQNFTLTVRPGSAPAITSANTALFGVGATGSFSVTATGTPTPTLAVSGALPTGVTFNASTGVLSGTPAAGTAGTYPLTITATNGVGTGATQGFTLTVQSGATGTVPAFTSAAAATFAVGTAGSFAVTATGTPTPTLSVAGALPAGLTFNAATGLLTGTPAAGAAGVYQLTFTATNSVSTASQTVTVTVTGTPVALPGRLAVSGPTDGSVTVFDPATGGQYPAGTAVVGNPFAGLGVQVRTAVADVDGDGTPDTIYVTGPGVAVQFAVVNGKDNTLLVAATMPYEATFTGGGFVSAADLDGDGRAEIVVTPDQGGGPRVTIFGRPTTGTTATVKANFLGIDDPTFRGGARSAIGDINADGTPDLAVAAGFLGGPRVSLLDGKTLFGTPTTLVGDFFAFPGSDAVTLRNGAYVAVGDVDGDGFADLIFGGGPGGGPRVYTLSGKLVSAGNLDAAYANPVTNFFVAGNTSARGGVRVGVVDADGDGRADIAAGSGSGLPGSVRVYFGKNVTSPAEPIAFQDLNVFGSTALADGVYVG
>NZ_CP042425.1|WP_149111106.1|3923864_3924917_-|DUF1559-domain-containing-protein
MTPTPRSTSTRSGFTLIELLVVIAIIAILIGLLLPAVQKVREAAARLKCANNLKQIGLALHNYEGTNGTLPPVFPAVVKAPYVGVVPPYFYSWSVLAQLNPFLEQTAIFNRMNLDQPMYLYPSLQVSTDNQFAVQQMIPIFLCPSDSMTAGVGGYGVSQFGSSNYAACTGSGATAGGAPYGSPWDSDGVFRAKIKGRFADITDGLSGTTAFSESTLGDGATTYGPTPPGPTRKWYANVSPPLTPAACGTPSSWNYQQPRGFQWVAGEVRCVSYNHFYPPNSPQYDCVTNVTTAGEQQYTSVGFKAARSYHTGGVNVLMADGSGRFVRDAVDPTTWTAVGTRGGGETGGDY
>NZ_CP042425.1|WP_149111105.1|3923626_3923839_-|helix-turn-helix-domain-containing-protein
MPTTSLDTIRCSSLLAALAAPERLRIVRFLAAGPQNVSTIAKNLCIPNNNLSHHLATLTNANFLRREHRG
>NZ_CP042425.1|WP_149111104.1|3922606_3923278_+|hypothetical-protein
MAKKSRGHGPTKVLFIGNSFTARNDLPGLIARLAGALGRQLEHRLIHAGGASLRAHWNAGRATEAIRDGGYDAVVLQEQSTLPAKNASRMHENVRLFDGAIRAAGARTVLYMTWARQNAPDSQQAITDAYAAIGKELGATVAPAGVAWQRFLRDNDGPALHDRDQSHPTVAGSYLAACVILAALFQESPVGAEVDVPGLSAGERAALQAAAGQAWAEPASEGS
>NZ_CP042425.1|WP_149111103.1|3921616_3922414_+|helix-turn-helix-transcriptional-regulator
MSKSQRVTAADEVAILRLMNECRELGDDAMAWQQRLISGLQKLTGGMVAAVGPTPPLRGELGVLQEWVGQQLGGGWPSESLRRKWEALAADPMAMQAHPAVSAFWAMPEPSLSLTRREIVPDHVWDRSPFVNDLLRADGMDEGLVSRADVPVIGGGYVLTVVRAKGEQAFSRRAGAVVAALLRELEPHLGRGLFLTSQPNLHGLSPRLRQVLGCLLDGDSEKEAALRCRLHPTTVHEYVKHLYRHFGVSSRAELLAYFLRRYPRR
>NZ_CP042425.1|WP_149111102.1|3919021_3921346_-|protein-kinase
MDTPTQPSESSEPPAVDLLPLPSRLGDYELTAALGAGGMGVVYRARHRSLQSTAAVKVLNPAIAHHTTARQRFLQEARLTAGLRHDGVVRVVHVGEDGPVLFLVMELLEGESLTDRLKRGPAFTTDETVRIGREVASALAEAHRQNLVHRDIKPGNIFLQHIPGRPPRVKLLDFGIARRQDADQSFTSVHALIGTPHYMAPEQVDDSRVGSPADVFSLGCVLYELVSGRNPFRGRSQAASLRLIAEYDPPPLNELFPILPDAFSTVVRDCLFKDPLRRPTAEDVERRLLQVEPEPDSRTALRTVSAAADTTETQKYRPNAKPTARRWVGAFALLIALGTLGCLGLWLDSRPPKPKADDANPVADRPLPVADKSQSVLSGWRLEQPPPLDEWLRGRRIRTVRQDGGAEFRSLLAALAAVRSGEAIEILDAGPYTDFAPLPDGSVGLSVPPDVTDIGIFSRTGASLRTTKYQVNKNIPPKNGRVCYAGATIAAGAGLRLHGLTFQADPPPQNTADASAWRLSIGGPCVVEDCLWLRAAHPRPEQYLVILAFDFRNSAAMPLTVRRCWVEGTVNTHVTNPGVRTEARIERCVFTDASQNLWLQLGHARWAFLENIFQADDCCVALGTTRFAPAKGQPEVLFGRNTFLSTARSPVRVERYEKGELAKVSVALFDNAFSGPGEPIHFAASQDARESRSWASQENWSTDHSGAAWLNFLEGRIQFVSQDPLAPDFARIENSPPGTGGAGLRGPGAVPSGPLSDALEWLAYLQARRGMVSP
>NZ_CP042425.1|WP_149111101.1|3918743_3918932_-|hypothetical-protein
MSPRRARYRAPPKDAVPAGVIPLSKDAEKDKGREANADAIREHPWAVIGITPGGTYGMVKQK
>NZ_CP042425.1|WP_149111100.1|3918278_3918683_-|hypothetical-protein
MNLSRAVYDPVLSELRVHAQLKGERQLYRRAIAEYLVGRDDFFAREAKYSLHPIRRDREDCLACGDVDGLDAVLLRELHFAGGSPAVARRRERGGHGPTTGPFTSSKPAGRVAPVPNSPLTESAFARRLVRETA
>NZ_CP042425.1|WP_149111111.1|3935584_3936193_+|RNA-polymerase-subunit-sigma-70
MSSEESVTHWLTQLRDGDGEAAQQLWERYFRRLVGLARVRLQSHPRRAADEEDVALSVFCNLCDGATRGRFPRLDDRDDLWRLLVTLTERKAINLARDERRLKRGGGAVLTGDALTRPGESTAGGFDQVPGREPTPEFAAEMAEEYQRLLTRLDDPGLRSIAVWRMEGESVGEIAARLGCAVTTVERRLRLIRQLWESEGGE
>NZ_CP042425.1|WP_149111112.1|3936189_3938667_+|protein-kinase
MNGPAPDTRPDLPPELARQVDQICCRFEAEWKAVRRGDPPPRLETFLAGGPVPARPVLLRELLLVEVHHRRSVGDEPRVNEYGDRFPDLDTGWLADHLGAPDTRSLPTVAPVQLPAFLDAIRDNGILDPSQTVTAVEEAGHARQVTDLADRLVNRGWLTAFQAQRLLAGRPHELVLGEYVLLEPLGTGGMGLVFKARHRIMNRVVAVKRIRPEAADDPTALRRFRAEIQAAAHLSHPNVVVVHDAQEASGELFLVMELCEGVTLHDLVKQRGPLPPAEACEYARQACLGLQHAFERGLVHRDLKPRNLIRCGKTLKILDFGLARLRQGPAAGSSTTEGTIVGTADYMAPEQADGRADVRSDLYSLGCTLYFLLAGRPPFPGGEILDKCVRHRIEEPESLARLRPDVPRRVREIVSRLMAKDPADRFQTPAEASAELAAVSHRDIPVISPLLDSAPVLDAPPTRPARKRRTPVRFGILLAVVAIGLTSYLVIRSGPLREGPSPAQPPASPLAWKKSKTLSLPIEHAGAYGLAFSSDGRLLAGACGNHETAGPTPAGRLCLWEVAEGRLVLDRELPAGPGACVAFSPDGQRLAWATGYWGHEVPGKLTLWDVAGRADICDVEAHAQGVCALAFQPRSDLLVTSGYEGKVFLWDARSGQPLGELTDARIAVFALAFTLDGKYLVVGADDGSVNVWELATRTRVQTLSAATGKPVRGLAYLSDGETLLAVTKQGEAPPANLLAWRRGDALPTVSLGDTNAYSLALSPDRATALVGCRDNAARLFQGQTRRALQTLTADQTFYSLAFSPTGQLLATSAGLDRPVQLWEPD
>NZ_CP042425.1|WP_168219520.1|3938831_3939560_-|formylglycine-generating-enzyme-family-protein
MVWIPPGRCMIGPDRVPAEMTGFSLARHPVTNTQFARFLAATGYTPPADGDAAVGTDGYANGAFLEHWIGRTPPKELLDDPVVYVSYRDALAYCAWAGLSVPGEFQWEKAARGPDGRTYPWGDAKPARRGVAHFGSRETVAVGQYTRSRSPYGCEQMAGNVSTWCQPGDADRPGERPPPRPTVALLHVGQPLHAAVRGGAFKRAGPETLRAFHRRRLSVARRNDWVGIRPSFPLPVRPANAD
>NZ_CP042425.1|WP_149111114.1|3939808_3941329_-|RNA-directed-DNA-polymerase
MTDTPTWLLHALPANAVVDEKLNATLSALAAALADNRDKPLVTAGLLTEIQGHLAHAQPFAAYEAAVNGIAGQVWQLFEAVHQRQNRPAKLAFLNLVVRHLTPGALAQLCRRWAKDADPAIRRAVGRVIETGAIHEVALPATKDGAWSPAGWRKGTVEVDLSRHKVGTAVQEANSVPPLANLRQLRELLGIRSAKQLGYFLLASDKDDGPYTRFTVPKRGGGERVICAPKPQLKWVQRRIHERILSGVPLADAAHGFVPGRSIVSNAAAHVGAAVVVKFDLKDFFPTIHSYRMIGLFARMGYSVGTAKIATADESASVAPVLARLCSYTPDPRAWGKAHAPQGAPTSPAVSNLICRHLDARLGGLARKLGGVYTRYADDLTFSFAATGIDLGRFRWWVDQVCQQEGFVMNADKFRVIRRSQRQLVTGLVVNDGVRPTREQRRAFRAVLHNCRRNGVVTEARGDPRFSQYLRGFASYLHMVRSTEGADLVRQVAELLDPPGGGEDKP
>NZ_CP042425.1|WP_168219035.1|3941411_3943394_+|hypothetical-protein
MRVPDDHPLNVTRAFRTAGAALAAVEAAREHGGAEVLDGLFELAVAETNAAVVVATLRALAERDTPLSRVAVRRAAGSRFALARQFAIHAMDRLDDRELDSAVVKLLTTDPSWVNRRAALTALAAVGRERRWEILRTADDPHWRVRHALGRVLTAWGASETDQQEINCRLAIEQFEEGINRTRRDALLAYLTYRWTGREPGDGTAFGAPDPFAVCPFWDWDAAVLAVRLKRMTAAERAAHVNAMPFLAGHEDGRVWKSAVSAIREHGESHHYRAVLALRADPRNGAEPAIERLLDGLDEERKHELTTGPFGRRSVGEREPLEAIAGSPFQRAAALTPTTAAGIVAEPTSETSWHVIEAAGRLAKVPIWEVEPLNPWTPPTVAKPSLPPLVAPLGAGVATTLVGPDRIAVSRVGVSGHYLLPVEGFVEAAAAGVNWFFWEPNYATLTAFSSRLSASDRRPFHFVAGTFEADGRRIRADVERALRELRVERLGIFFLFWVQSWDRLTDDVRDTSAALRAEGKIAAVGLSSHRRPLLVRAMADGWDVVMARHSAAHRGAETELFPAVPPGTTLITFNNLCYGRLLEPTHGLTPPTAADCYRYTLSFPQVAACWSAPATVEQLRDNLAALREPELDPGRRDDLRAFGAKLYQHEKVFERLVRML
>NZ_CP042425.1|WP_149111116.1|3943784_3944000_+|hypothetical-protein
MTPGKLGTASGSCPHARQGVAAGTVTFTYPGAAKLSRALRLRGVVPDFRPPDMILADAAHHELPDADAPVT
>NZ_CP042425.1|WP_149111117.1|3943983_3944622_+|arylformamidase
MPPSPDRRVLDISRPVGADTAVWPGDVPFTFDLAGRKAAGASANVGAISGSVHTATHCDAPFHFDDAGETVDRLRPELFLGPAWVVDVRGASAWQPRVEALGFSATPRVLFRTGGWPDTARFPAAIPVMEPTLPGWLAARGVFLIGVDVPSVDALDSEALDNHHALGRAGILIVEGLWLDDVPPGRYEFAGLPLKLVGADASPLRAVLVSPA
>NZ_CP042425.1|WP_149111118.1|3944721_3945342_+|hypothetical-protein
MIRLYIIRAVLIAAVASTCYWLGGECSLGLAILIWAGVTTGACALGAALLRTSRVGEITWRNRAAGYLIPWGWRLSRGRLWVAAVFSWVTWMAVGGAAFAMRPGAMTEPSTTGVRAALFAAWVIDAAALVYVLGTIWQATPGSRVRSLWKLVTVITAVLGASVGLYVTGRPTEALMFGGGPPLAVGGGMGLFVLTVLIFGRNTRWN
>NZ_CP042425.1|WP_149111119.1|3946037_3946721_+|transposase
MYVLITGIGWEFVPPGFPCGKAIKTRPDRWLAIDAFRTAWQPLADRYQDLHGINWDQVLIDGSKRPSKRGTLTGPNPADRTKSGTAIHLATGGRGLPLGAVVAAANVNDGMQTRAVVDDFVIRPRRTGRTPTRPPGPTPRSRGRRVRERAGPGAGRGGRLPHDRPAAGPRRPRAGRCGPGSREGTRCSPRLAASAAGSTGTASDTSGGFNLPPSLIFLRHQANGFFR
>NZ_CP042425.1|WP_168219036.1|3946841_3947282_+|GatB/YqeY-domain-containing-protein
MSLHDELKARVIAAVRGGDGLTRDTLRTILGEAQTEAVRRTGEVTDEIVLGVVRKTVAGLKETIPLAKQAGRDTAPREVELALLESLLPKAWDREAIAAALAPLRDELRAAKNDGQAMGVAMKALKARGATTGPDDVKAVVAAVRA

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Crispr_ID: NZ_CP042425_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_9

4274574-4274758

Orphan

Consensus_repeat	Method
GACAAAGGGATGGCTCACTTCAAGGGCTGCAAGAACCT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP042425_9

>merge|NZ_CP042425|9|4274574-4274758|PILER-CR
GACGAAGGATTGGCTCACTTCCAGGGCAACACGAACCTCACCGAACTCTGGTTGGGCGTCATGCCGAAGGTGACGGACCGGGGGATGGCCTATTTCAAGGACTGCAAGAAACTAACAAAGCTGTGGCTAGGGGGAAATTCCTTAACGGACAAAGGGGTGGCTCACTTCAAGGGCTGCAAGAACTT

>NZ_CP042425|9|1|4274574-4274758|PILER-CR
GACGAAGGATTGGCTCACTTCCAGGGCAACACGAACCT	CACCGAACTCTGGTTGGGCGTCATGCCGAAGGTGACGGACCGG
GGGATGGCCTATTTCAAGGACTGCAAGAAACTAACAAA	GCTGTGGCTAGGGGGAAATTCCTTAACGGACAAA
GGGGTGGCTCACTTCAAGGGCTGCAAGAACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149111355.1\|4269896_4270448_+\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|224766
NZ_CP042425.1\|WP_149111359.1\|4275295_4277086_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111356.1\|4270493_4271243_+\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|376667
NZ_CP042425.1\|WP_168219064.1\|4261783_4263916_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|316042
NZ_CP042425.1\|WP_149111362.1\|4281643_4281883_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111365.1\|4283244_4283910_-\|DsbA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|239322
NZ_CP042425.1\|WP_149111352.1\|4266431_4266719_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111357.1\|4271530_4272112_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|132044
NZ_CP042425.1\|WP_149111364.1\|4282641_4283151_+\|DUF417-family-protein	unknown	unknown	gnl\|CDD\|282127
NZ_CP042425.1\|WP_149111349.1\|4263943_4265092_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP042425.1\|WP_149111353.1\|4266715_4267513_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111351.1\|4266202_4266445_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111368.1\|4286728_4288273_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235870
NZ_CP042425.1\|WP_149111366.1\|4283926_4284364_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP042425.1\|WP_168219066.1\|4280884_4281493_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379605
NZ_CP042425.1\|WP_149111350.1\|4265725_4266058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111367.1\|4285138_4286587_-\|3-(3-hydroxyphenyl)propionate-hydroxylase	unknown	unknown	gnl\|CDD\|235728
NZ_CP042425.1\|WP_168219065.1\|4268949_4269840_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176903
NZ_CP042425.1\|WP_149111363.1\|4281915_4282515_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP042425.1\|WP_149111360.1\|4277740_4280866_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|274368

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149111355.1\|4269896_4270448_+\|flavin-reductase-family-protein	gnl\|CDD\|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	8.58754e-25
NZ_CP042425.1\|WP_168219064.1\|4261783_4263916_+\|AAA-family-ATPase	gnl\|CDD\|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	3.04302e-29
NZ_CP042425.1\|WP_149111356.1\|4270493_4271243_+\|TSUP-family-transporter	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	6.27461e-17
NZ_CP042425.1\|WP_149111357.1\|4271530_4272112_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|132044	TIGR02999, Sig-70_X6, RNA polymerase sigma factor, TIGR02999 family. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found in a variety of species including Rhodopirellula baltica which encodes a paralogous group of five.	3.41427e-64
NZ_CP042425.1\|WP_168219066.1\|4280884_4281493_-\|hypothetical-protein	gnl\|CDD\|379605	pfam14417, MEDS, MEDS: MEthanogen/methylotroph, DcmR Sensory domain. MEDS is prototyped by DcmR and is likely to function with the PocR domain in certain organisms in sensing hydrocarbon derivatives. The MEDS domain occurs fused to Histidine Kinase and as stand-alone version. Sequence analysis shows that it is a catalytically inactive version of the P-loop NTPase domain of the RecA superfamily.	6.3294e-40
NZ_CP042425.1\|WP_149111365.1\|4283244_4283910_-\|DsbA-family-oxidoreductase	gnl\|CDD\|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	3.02209e-93
NZ_CP042425.1\|WP_149111364.1\|4282641_4283151_+\|DUF417-family-protein	gnl\|CDD\|282127	pfam04224, DUF417, Protein of unknown function, DUF417. This family of uncharacterized proteins appears to be restricted to proteobacteria.	7.87177e-35
NZ_CP042425.1\|WP_149111349.1\|4263943_4265092_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.01711e-14
NZ_CP042425.1\|WP_149111368.1\|4286728_4288273_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|235870	PRK06834, PRK06834, hypothetical protein; Provisional.	2.91593e-99
NZ_CP042425.1\|WP_149111366.1\|4283926_4284364_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.85701e-08
NZ_CP042425.1\|WP_149111363.1\|4281915_4282515_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.85617e-21
NZ_CP042425.1\|WP_149111367.1\|4285138_4286587_-\|3-(3-hydroxyphenyl)propionate-hydroxylase	gnl\|CDD\|235728	PRK06184, PRK06184, hypothetical protein; Provisional.	0
NZ_CP042425.1\|WP_168219065.1\|4268949_4269840_+\|hypothetical-protein	gnl\|CDD\|176903	cd08894, SRPBCC_CalC_Aha1-like_1, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	5.33182e-55
NZ_CP042425.1\|WP_149111360.1\|4277740_4280866_-\|PAS-domain-S-box-protein	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.15746e-50

>NZ_CP042425.1|WP_149111357.1|4271530_4272112_+|sigma-70-family-RNA-polymerase-sigma-factor
MTTDLTHILNAIDAGDARTAAELLPVVYEELRKLAAAYLANESAGQTLQPTALVHEAYLRLVGGANPETWNHRGHFFAAASVAIRRILVDNARRKHRQKRGGEFNRLGLDDVSPALPEPAEDLLALDEALSKLASVHPREAELVQLLYFGGLTLPEAAGSLGISPRTAGRLWSFSRAWLRREIEPTGDPGENL
>NZ_CP042425.1|WP_149111356.1|4270493_4271243_+|TSUP-family-transporter
MAPFTDDPLVLPVVGVVFLATLVRSAFGFGEALVAVPLLGLIVPIRVAVPLATLLSIAIAALILAQDWRHIHVRSAWWLTLPTFVGIPIGLFLLTEVSPGPVKVAMAAVIIGFSCYCLFGRRKPQLSDDRFAWAFGFGAGILGGAYGMNGPPLVVYAALRGWSPEHFRATLQGYFLPASAAGMLGFWLAGLWVPDVTRYFLLSIVPAAFAVLIGRVANRRMHPEVFVRYVHVGLIGIGLVLLAQSVWGE
>NZ_CP042425.1|WP_149111355.1|4269896_4270448_+|flavin-reductase-family-protein
MKAHKKADFPTDHIRRFLEPGPVVLVSFAHAGERDIMTMGWHTILGYNHIGCYIWDQNHSRKLTRASKDCVFNVPTFELIDAVIGVGNTHGPEADKFAVFGLTPAKAKTVGAPRIAECFASFECRLVDDSQADKYSLFTFECVRAHVATSPKYPKTVHYRGDGVFMIAGENKSYRRTFKPEML
>NZ_CP042425.1|WP_168219065.1|4268949_4269840_+|hypothetical-protein
MIDAIQVTHAPARQAAVIRFHIPQKELPAVMPQAVKELLAVLGEQGLQPAGPLFNRYLSMAGGKFEFETGFPVDKPVTPSGRVVPGALPAAKVARAVYTGPYDQLHHVWHEFGARVQAGGHSPAHGLWESYVYGPESSLDPTTWRTELNQPLASDNPAALRTEREIAATPREIFAAFERPESLAQWWGPDGFTNTFERFEFKPGGKWVFVMHGPNGTDYPNESVFRETRPDKIAIELVSQPHFTLTVTLTARGDKTHLVWAQEFDSREIAEKLRPICDPANEQNLDRLQAVLAGSR
>NZ_CP042425.1|WP_149111353.1|4266715_4267513_+|hypothetical-protein
MKFPAPHAPGLAAGRHDPLQEYFKRRRDPATGVVAYVDPPPDAERDAAFRDLQARVAPLEAAASAHRDAVRGLADRCRAGWGGGAEANGRRPAVAPAARRRLYTAAEGERVVAAGAAAIAGWYDLLTATHAGADAESAVRHVMLVGGDWSFPGDPPVIALLQDAGAVAALRRAFYDAAFWRAVAGRPTVAEVTFFLAGAAAAKSDNWDLFQAAMTMPRRGTMRPPAGRSPSGIVRFVAHLWEARRVDQPIDAPGRTLSGMAGSRP
>NZ_CP042425.1|WP_149111352.1|4266431_4266719_+|hypothetical-protein
MTTSESVRLPTAEKVTETETMLLIFAHGWETELSTGPADCAEAANPSGTLCTGGEANSFRAADSRASIEDRPNLVHSAAPTRDHVPAWSGLEITG
>NZ_CP042425.1|WP_149111351.1|4266202_4266445_+|hypothetical-protein
MTFQEAVVELLNKHAKAELSPSAQRGSAFNRAKTVRFKKGKGGVYEGKDADGTEVLVYFNDQAGVISCTEIEADAPDDDE
>NZ_CP042425.1|WP_149111350.1|4265725_4266058_+|hypothetical-protein
MAHYFYTDPIAAAWMAKHFRFKMSAGKFCLQAESVDTFLRLLAEGMEIDKIVVQKESIALLDPRLGDMVEDDARGKLRILAEQHFPYTANLKQIVQRNGRAFIFPQKANE
>NZ_CP042425.1|WP_149111349.1|4263943_4265092_+|tyrosine-type-recombinase/integrase
MASVVNDPNGRRRIQFVAPDGSRKAIRLGKTDRKTADSICRHVEALLGAKLSGQAIPRDTAVWLSGIGGKLRDRMVAVGLAEGVSAVPALQAWCKGYIAARTDLAPRSVARLEFAARLLVEHFGSDHRLDAVTAGDAQGYARWLATTRAANTVRRQLGWAKQFFGAAVKHEVLTRNPFVGLAANTRPDRSRDHFVTRDETAKIMDTCPDGEWRLIVALCRFAGLRCPTEVLALRWADILWDQDRMTVANGKTGKITGEPFRTVPLFPEVRLHLEVAFDQARERAEHVITRYRDCNTNLRTQLARIARRAGVPMWDKPFVNMRASCATELIQTYPAYVVAAWLGHTQAVAEAHYWQVTEDHFKKAAQNPAQQRAAEGAANERE
>NZ_CP042425.1|WP_168219064.1|4261783_4263916_+|AAA-family-ATPase
MTPLERVLEKLPTARKSGGGWTARCPAHDDNSPSLSVNRGDDGRILLHCHAGCRFADIVRALGLTPADLRPEKEAHRAKVPHMAVERGNGFSSAEAVIRCLARKSRPPSGRWEYHDAGGAMVGLTLRWDGPRGGKRYSPVALIDGRWQIAGMPSPRPLYRLTEVRKAKRVVVTEGEKAADAFRKLGFTATTSAGGADAVSRSDWTALVGLLGVWIFPDNDAPGRRYAEAVAAEIAKHSPATVVRVIELPGLPEKGDIVDWIDAHGEAAEPDGMRAELEAIAADVTPQRGGYAAAKPRSRAVLNLVCLADVEPTEVPWLWPSRIPLGRLTLLVGRPGAGKSFLTCDIAARLSVGAPWPDGGTAPLGSTLLISAEDDTADTIAPRLNSAGADLKRIHLLTAAKVVGEDGKERVVAFDLQNVDLIRDALDQLSDCKLVVIDPVGSYLGGRVDAHRDNEVRGVLAPLAALAAERGVAVLIVCHTRKAQSSFADDAALGSRAFVGLARCVLHLAADDKDRDRKLLVPGKSNLGEPAAGLAFTISGKPAHLEWEADPLDGLHADDLMAPPDGSRQVGGPKPRARDAAVDWLTRVLENSPLLVREIEAQAKAAGLAWRTVRRAREELAIIPHKQAFSGGWAWQLPNEGDHAHPRTGPRREAGGHLRENDAKNSDNRLQNVEGGQVQHNSAAFDESNTVSGIDVADGSLFPEARGLPD
>NZ_CP042425.1|WP_149111359.1|4275295_4277086_+|hypothetical-protein
MPRETDAADSLANEGSPEADRHLAENFGMTLKQLREFDPQTLDVTRACKFLGLPLKRFDLLGSQSGARGRWVDSIAREKRNLIETFPEASQDVKEMLEAIRKFALRKCLNPDSPALMDGRRPQDEDFGGGGFLGRNRFFLWGGTLVLFAFACGLVAVFMPKDGPSKQRTTVVDTAPPSSGKGASTVRTNQPIPPSEPVANKPTAVPNLQVNKPDPDPRPTTDPAPRTVTSFNGYWTGQHSNSDGWKGYGKLTLTEDGDGAISGTWFATKVSGRREGKKTSVLRGKDDGQSMQLNCTIEGGVMKIEYSVTKGSGETAYTGKSNLRRVNVIVRAKNKLLDDAVVTVELDGKRVTEWPNNLLEVGVPARPGQHQVVIRSAYKGVFYSQTFDAVTVSSDEAIVLDTNKLKVDQPQRVAWTHSAGSFTYQGNGKWLEAPQNGGKYNFVEVVRVTDYVELHDASRNCSVRLLAGSMHLKGLKGYPEFKEYYVGRWEKEATPAPPRPEDLIGMWNSDFGKVSLEITKSGVISGYWVQDLNKKGVITGGAFTPGTRTLTFLIAQPWNNEKGSATFTLSADSTKLDGTWKHSSGNGKWQMTRVAR
>NZ_CP042425.1|WP_149111360.1|4277740_4280866_-|PAS-domain-S-box-protein
MPINDNQADEVQRLRDTMRELVALSTLPAAWAGYAPDGVARSLAGVLRDALSLDLVYVLVRGFGNVELALGQGFAADALQLRVIADGLAPVLNPQPPVTVADPLGGGEFRVAVTRFGHAGDLGVVVACSRRSDFPNESDRLLLSVGANQTAIVLQRKRAERALRESEERLRVTLSSIGDAVIATDAEGRVTFMNAVAEALTGWPLADAAGRQLPEVFRIVNEYTREPGANPALRALNEGVTVGLANHTVLIARDGTERPIDDSAAPIRDGKNPSMGAVLVFRDVTERKRSESEAVQLAERLRLALDAGDLGTWEWNPATDEMTVSPRASEMYGTPVGVPHGREQGRMMIHPDDRERARLAAEKAVAERTDYDIEYRLADRPAWVAAHGRGLYDAAGRLVRVHGVVQDITERKRAEDEAAGLAERLRLALEAGGTGVWEWDVVTGRITWSDQVHAFYGLAPGEFDGTFEMFARHLYPDDAARAGDAIRASVEDDVPYRIEYRIVPKGGGLRWISTAGRVIRDAAGKPLRMVGATVDVTERRLTEDTVRASEKRFRTLFDSMDQGFCVIEVTFEGGRAADYRFVELNPAFERHSGLPRNLIGASIREAVPGLEEFWFDTYGRVAATGEPTRFVHPAAPLGRWFEVYAFRLEDPDRCRVAVLFADITDRKRAEEELRDQDRKKDDFIALLAHELRNPLAPIRNGLQVLRLGGANPEPLARARDMMDRQLTHMVRLIDDLLDVSRINRGKMELRRGRVELADVVGSAVETARPALDVGKHELMVTLPATPVALDADLTRLAQVFSNLLTNSAKYTPKGGRVWLSAERTDGHVRVTVRDTGIGIPAESLPTIFDMFSQVDRSVERSTGGLGIGLALVKGLVEMHDGTVAAASEGEGLGTTFTVTLPVVTRVEASVPLVTEAPTRTPARRILVVDDNRDGAESMGDMLSMLGHEVATAHDGLGAVERAEAFRPDVILMDVGMPRLNGLDASRRIREQPWGQGIAIVALTGWGQENDRERSREAGCNAHLVKPVDFTDLQRVLAEVTR
>NZ_CP042425.1|WP_168219066.1|4280884_4281493_-|hypothetical-protein
MTETKPPIQLAGSTLNRTRHACAFFNSREEEDGVLLPFMKEGFERGERQCHIVDPEHRPDRMRRLAEAGVCPDCAQVDVRPWEAAHLTGGRFDKEAMLALVQESMESHKGSGLTRWWGNMEWALTGAAGVEDLIEYESRLNYIIPKYDDVVVCTYDLNKFGARVVMDVMRTHPMVIIGGILQENPFYVPPDEFLRELKGRAA
>NZ_CP042425.1|WP_149111362.1|4281643_4281883_-|hypothetical-protein
MSLSPDELRELAKYVLLTRPDEIGCDDWLGYAPSYAELIATSQPVPEPLQKAAGHLDLCPECAEEFRALMEALKEGGGV
>NZ_CP042425.1|WP_149111363.1|4281915_4282515_-|sigma-70-family-RNA-polymerase-sigma-factor
MTERSNEDWLQLLGGTDEMAVAELREFLRRGLRRGLAGWAAADDGFIEDMAQEGTLKVLSGLTTFRGDSRFTTWAVTVAVRVAFTELRRARWKDVSLDRLVEDAPSQQPAAAPAVEPSADSKAAILAEMHRVIATGLTERQRQALVAEFKGMPQAEIAARMGLTRNALYKLTHDARQSLKRGLEAAGIDGDGVREAFDL
>NZ_CP042425.1|WP_149111364.1|4282641_4283151_+|DUF417-family-protein
MTTLTTTTSPAARIDQALVALGARAEAIGVHALRYGLVLILLWIGGMKFTAYEAEGIRPFVENSPFFSWTYPVFGVRGMSAILGVTEILVGLMIAARPWFPRLSAVGSLLAVGMFLGTLSFLVTTPGTFVKDLGGFPAISVLGQFLIKDVALLAASIWSFGEAVRAIRR
>NZ_CP042425.1|WP_149111365.1|4283244_4283910_-|DsbA-family-oxidoreductase
MVTIDIYSDVICPWCFIGKRRLEKGLAGQEATVRWHPFELNPNMPPEGAERRAYRIKKFGSWERSLELDAQVGRAFAGEGLAFNAEQMARTPNTFDAHRIIWLAGEKGVQDAVVEALFKAYFTDGRDLSDRATLAAVAVEGGLDAKEVHDLLATDRGTTEVRAWEQKGQRLGISGVPFFVINGTVALSGAQPPEMFREAFEQAVATGDTCGVDPASGERNC
>NZ_CP042425.1|WP_149111366.1|4283926_4284364_-|GNAT-family-N-acetyltransferase
MPTVEPLAVLTPADQEAIIAPLGAFSRQRGFAWAPVSLALVLKDEHSVVGGLTGGTQFGRLRINILSVAEHLRGGGWGRRLVEEAEKLAVRVGCHSAWVDTFRFQSPGFYRRLGYAVFGELPDYPTGQTRYFLSKRLVAAPGKMP
>NZ_CP042425.1|WP_149111367.1|4285138_4286587_-|3-(3-hydroxyphenyl)propionate-hydroxylase
MNQTDVLIVGAGPTGLTLAIDLARRSIHCRIIDKSPLFFPGSRAKGVMPRTLEVFDDLGIVDAMVAAGGPFPPFRGYHGEAVLWDRTIHQMGGFPVLEPSPDVPYAQFHMVAQWRTEEVLRDRFATLGGRVELATELSGIEQDGDAVTATFATGESVRCRYLVGADGGASFVRKSMGVSFVGETDATDRSIIADVKAAGPDRDHWHMWTNPGNPANRVSLCPLPGTEYFQFVAPVTTDDVPDLTLEPLQGIFDRRSGVTGVRLTDLRWATVYRVNVRMAERFRVGRVFLAGDAAHVHSPAGGQGLNTGIQDAYNLGWKLGAVLAGASEALLDTYEAERLPVAANLLGITSALHKQGFWSKGAAPQNADIDINQLKLNYRGGPVSQGRSAGPLQPGDRAPDAPRRTGGRLFDVFRGPHSTLLAFEPATGKYGDSVRVCSVAPDEAEVRRIYGIEHGYVLVRPDGYVGLIAPDEAAVRRIEYLC
>NZ_CP042425.1|WP_149111368.1|4286728_4288273_-|FAD-dependent-oxidoreductase
MTEDTVVYDVIIAGAGPVGLFLASELRLAKLSVLVLEQAAAPHSPLKQLPFGMRGLWGPSIEAFYRRGMLEQLATQPHVDLQPRPGSTASGPQRRGPGGHFAGIQFDATNIDSSRWTYRLSGPGDGQMGTEMEHVERVLTAHALSVGVEIRRGQGVEGFEPSDDEVTVHAGGQRYRTRHLVGCDGGRSTVRKNGGFEFVGTDPEFTGYSVRVDIADHSVLPMGRHHRFFPFIKGAAGMYTQWEPGAIAIADFDGGAGHRSGPLSLERVQAILRRVSGTDVTLTALHVASTWTDRAMQATTYRKGRVLLAGDAAHIHSPLGGQGLNLGFGDAMNLGWKLAATIRGDSPDGLLDSYTAERHPVGARVLDWSRAQVALMQSPALQGVVRDLINTRDGATYFAERVWGVSLRYDLGGDHPLVGRSCPDFEMEDGTRIGTLLREGNGLLLDFGRSLRSLDGLWGDRVRHVAGDVKDRLGLSAVLVRPDGFVAWASDAAPSREDVTRAAARWFASIERPA

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Crispr_ID: NZ_CP042425_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_10

4379925-4379998

Orphan

Consensus_repeat	Method
TTTCTTCCCGTTCGGGAAGATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_10

>merge|NZ_CP042425|10|4379925-4379998|CRISPRCasFinder
TTTCTTCCCGTTCGGGAAGATTTGACCTGTTTCGAGCCCATTTTGACTGTTTTCTTCCCGTTCGGGAAGATTTG

>NZ_CP042425|10|9|4379925-4379998|CRISPRCasFinder
TTTCTTCCCGTTCGGGAAGATTTG	ACCTGTTTCGAGCCCATTTTGACTGT
TTTCTTCCCGTTCGGGAAGATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149111450.1\|4379481_4379907_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111451.1\|4380120_4380651_+\|YceK/YidQ-family-lipoprotein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111455.1\|4385732_4386194_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197715
NZ_CP042425.1\|WP_149111458.1\|4387063_4387411_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111454.1\|4385217_4385598_-\|DUF1376-domain-containing-protein	unknown	unknown	gnl\|CDD\|369218
NZ_CP042425.1\|WP_149111387.1\|4382972_4383215_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111447.1\|4378050_4378269_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111388.1\|4383788_4385165_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP042425.1\|WP_149110579.1\|4374343_4375720_+\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP042425.1\|WP_149111446.1\|4374012_4374345_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111453.1\|4382140_4382479_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149109166.1\|4376548_4377781_+\|IS701-family-transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP042425.1\|WP_149111456.1\|4386190_4386541_-\|DUF1064-domain-containing-protein	unknown	unknown	gnl\|CDD\|283910
NZ_CP042425.1\|WP_149111445.1\|4373670_4373886_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111448.1\|4378479_4378959_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111444.1\|4373012_4373681_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111452.1\|4380943_4381612_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111457.1\|4386530_4386791_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149111449.1\|4379005_4379296_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110580.1\|4375848_4376457_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149111454.1\|4385217_4385598_-\|DUF1376-domain-containing-protein	gnl\|CDD\|369218	pfam07120, DUF1376, Protein of unknown function (DUF1376). This family consists of several hypothetical bacterial proteins of around 95 residues in length. The function of this family is unknown.	1.25197e-33
NZ_CP042425.1\|WP_149110579.1\|4374343_4375720_+\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.68907e-38
NZ_CP042425.1\|WP_149111455.1\|4385732_4386194_-\|hypothetical-protein	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	0.000770179
NZ_CP042425.1\|WP_149111388.1\|4383788_4385165_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.01407e-35
NZ_CP042425.1\|WP_149109166.1\|4376548_4377781_+\|IS701-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.39862e-67
NZ_CP042425.1\|WP_149111456.1\|4386190_4386541_-\|DUF1064-domain-containing-protein	gnl\|CDD\|283910	pfam06356, DUF1064, Protein of unknown function (DUF1064). This family consists of several phage and bacterial proteins of unknown function.	1.89686e-12

>NZ_CP042425.1|WP_149111450.1|4379481_4379907_+|hypothetical-protein
MNRQLLLLIALTATLAGCKKAGQKPADQKAADKANTPAAVAEEPANDDPPGMKMWTDEQLEQQVREDMKFTSLTLKKESRDKFTGTGTTAVGKAYKLVVRARPGEYRIDAEAAVQPPGGNDKKSSHWCAETVTPKWKDGAK
>NZ_CP042425.1|WP_149111449.1|4379005_4379296_-|hypothetical-protein
MNPEHDAFFTHETWKNQKMDSVVINAPATGLSFLVHFYGEQIKGMQRLIGLIKAEAQKGAGREGDLALTTLECDVARLIDSKERMERAANSRAPVN
>NZ_CP042425.1|WP_149111448.1|4378479_4378959_-|hypothetical-protein
MRYEERIEPTPEMLAKGTVIIHRDSDGNFLSAEPRHITILQWLDDMRLLSPECVWAAHRYMACQHAYERRIRGKGTFLDRSVGEGEGDPFEPTMADDYLKMVRRLTRGETEIIDRVCAREFQVGSRKWLFSERERFHEVFEKLAAAVEAVHDSRLSGNG
>NZ_CP042425.1|WP_149111447.1|4378050_4378269_-|hypothetical-protein
MLRIYLLTLASVAVLIGANEYCEHHNGKGLLARSGIERFVDRQLGQSGNGEPGLFKLVTTGFEANSTIGGCQ
>NZ_CP042425.1|WP_149109166.1|4376548_4377781_+|IS701-family-transposase
MDARKLAKLRRELTAFLDEVAGTLGNARRRRWCDAYLRGILLDGHRKSVEPMAARLKTIEQGDADYEQALQQFLNQSPWDTGEVRGGLQAWVARRFGTAGVVIIDDTGFPKQGTHSVGVARQYTGTLGKVASCQVAVTLQFATAKEVVGLDAQLYLPQAWADDADRMARAGVPVAVGYRPKWQMALAMLRQAAGHGFCGVVLADSLFGTVTEFREQLAADGRTYFVGIDSTLKVVAADADLGPVPPAGRTGRPPTRPAGVRAGAKSPNVKEWALGRVADFRAVMWRKGTKGKMAGRFAAWRVRPAHKLSSGREPGGACWLLVEWPAGADQPAKYFFSNLPAATSLKRLVAAAKSRWWVEHSYRELKDELGLDHFEGRSWRGWNHHAVLVLMAYAFLQDLRRTRRKKVSPG
>NZ_CP042425.1|WP_149110580.1|4375848_4376457_+|hypothetical-protein
MAAKKNQERSGAGMDKEAVAVESVRQFVWSGFYDADGIVEMIDEAVLSPGELDHGWLRARIEEEFRKKRADELAWPAITDCDRLDQVFELLEQQGILALQNAGYTQDNGLDDVTQFYHEAGGEQSGIGGYCFYHGQDLERVMENGDLHLTYGDIRGDDEKGIEIGRRIKRALETAGFTVVWDEAIKTRLLVKGIKWQRRLSE
>NZ_CP042425.1|WP_149110579.1|4374343_4375720_+|IS66-family-transposase
MDEPACPRCRDLLKRVAELEAQVAELTRKLEEAVRAGKRQAAPFRKGPPKPDPKPPGRKSGDAHGTHGHRPPPPPEQVAECHEAHLPDACPHCRGRLVETGTADQYQTEIPRTPLIRKFRVHVGHCEGCGKRTQGRHPLQTSDALGAAASQVGPDAQAAAAVLHTQMGLSHGKVASAFRTLFGITLTRGASARIDLRAAARLEPDYTLILDDVRSSEQIAADETGWRVGGHPAWLHAWVGDRATAYGIDSKRSADALERVIGADWSGVLSHDGFASYERFEGAIHQQCVAHVLRRARDLLATATRGAVRFPRQVIALFTEAIHWRNGYVPGTWTDNQLDAHRVSFDDRLLDLVRRPRAVPEYATLARHLRNHFEQWFAFVFDPRIEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAQAQGVLMSVFETCRRQTLSVVDHISQTLRWFGNRLLTRPPLFG
>NZ_CP042425.1|WP_149111446.1|4374012_4374345_-|hypothetical-protein
MPRYYQISPRSTALGPDGALNKYIFFRYSHGHEEETGRREEMLMPSIDELIQSYGTIATIASIGCTSPNPMEKEAFSWIYHHARENLDTLISCKNEEEPAVTKVAIVSES
>NZ_CP042425.1|WP_149111445.1|4373670_4373886_-|hypothetical-protein
MARIANGESLLCRAYLGNEDIEVRPTFDQRLTAYKELAQYVAPKRKAVEHSGSIGTHEERLEDLHDLDNAQ
>NZ_CP042425.1|WP_149111444.1|4373012_4373681_-|hypothetical-protein
MRSELVIARRLRDDFTYYAPRALRIRTKTGTVDPFRLNKAQHHLHTQVEAQRASTGKVRVIVLKGRQQGISTYIEGRFYWRVTHRKGCQAFILTHEQQATDNLFKMVERYHEHCPSLLKPQTKASNAKELVFGRLDSGYKLGTAGTKGTGRSSTIQLFHGSECGFWPHADEHAAGVMQAIPNQAATEVFIESTAIRPAESRIGFIPPARRVGSSPPPAKAPG
>NZ_CP042425.1|WP_149111451.1|4380120_4380651_+|YceK/YidQ-family-lipoprotein
MTNRQVRAALLLSCFSTAGCGTIANVATRGPEHGGMIPFGGVKQDLTFITSDSNLNINQKAPPGTYASRLSIILTTLDLPLSLVGDIVTWPFVELYALSNGIQPSSATHSIRSSAAVQFPADVPVSSVSNMPSVRMPSVPASSTTSQIIPQEAKTQPLPTPVEPLTQNGNPLLPSQ
>NZ_CP042425.1|WP_149111452.1|4380943_4381612_-|hypothetical-protein
MSNNLTDALSRLLLSPASGEFANIWNGAVSRCIRITEPLQSRITEQEEEIQLIRKLNSDQKALSGNIIRSLEEENAKLKAVAQCPYISTGQDGTSHCRLAEGSARLKVGGDDMAILTALDAACIHIEPENDDGFASGCRMLTPHDALKSMRPYLHPQQQPAALPVVSGKDIVQNFREYAFEIPLGKENKHRGASEYNWAIYHLKMLEAALAALQSNDGGGNE
>NZ_CP042425.1|WP_149111453.1|4382140_4382479_-|hypothetical-protein
MLTELLSRICALQKGYGKTQAELETLVEGFSWALVGYPMSDVNLAFQAYIVTQSDIPAPADIIKLIRSNKQSDEATPPTVSQLLEYRSRGIPLSPKQQADLQEYERSGAHHG
>NZ_CP042425.1|WP_149111387.1|4382972_4383215_-|hypothetical-protein
MRDIFGNPFRPVAFAAAWLTDTAVAIAQGMYESRDFAAMPILADALQDAGCDNEDILNHCRGPGPHVRGCWVTDAVLNKE
>NZ_CP042425.1|WP_149111388.1|4383788_4385165_-|IS66-family-transposase
MDEPVCPGCRELSKQVAELTAQVAELTRKLEEATRAGKRQAAPFRKGPPKPDPKTPGRKSGDAHGTHRHRPSPTEPIAERHDANLPDACPHCRGRIVETGTADQFQTDIPRAPLVRKFSVHIGHCESCGKRTQGRHPLQTSDALGAAASQIGPDAQAAATLLHTQMGLSHGKVASIFQTLFGITLTRGASAQIGLRAATRLEPDYRLILDEVRSSEQIAADETGWRIGGQPAWLHAWVGDRATAYAIDSKRSADPLERVIGRNWSGVLSHDGFASYERFEDAIHQQCVAHVLRRARERLAGATRGAVRFPRQVIGLFTEAIHWRNEYVPGAWSDDQRDAHRVSFDDRLLELVSRPRAVPEYATLAKHLRNHFEQWFAFVFDPRIEPTNWQAEQAIRPAVVNRKVWGGNRTDSGARAQGVLMSVFETCRRRARSVVDHVGQTLGWFGNRLLPRPLLLAR
>NZ_CP042425.1|WP_149111454.1|4385217_4385598_-|DUF1376-domain-containing-protein
MAENNQWYPFYTGDYARDTAHLSLLEHGAYRLLLDHYYATGSALPNDPEKLYRICRARTPNERKSVLSAVNEFFHQDGTLLRSTRCDREIAKRLNISKTRSANAMQKQSKGSANGSTKDSTKEVLD
>NZ_CP042425.1|WP_149111455.1|4385732_4386194_-|hypothetical-protein
MTEEQSPLYKMRFEIELVELVTRGYTAKQVADKLAVSEFTVRRICKKHRVSVDREKPRSKPRPEHKRVMPSQADDFLPLGKMASEKPDPIRLAKESLIDAYLLKLTKPILDIRDDGFYLRGKPANLSDVMKETNRHRIGWGLEQVVTNPAWAV
>NZ_CP042425.1|WP_149111456.1|4386190_4386541_-|DUF1064-domain-containing-protein
MPRSRASWGRKGKYNNTRTCVDGIWFDSKLEAARWQELLLLQKAGEITDLRRQVPYRLDVNGFLICRLIVDFTYLDSATGKLVTEDTKGVLTPECAIKLKLMRAIHGIDVQLVRKK
>NZ_CP042425.1|WP_149111457.1|4386530_4386791_-|hypothetical-protein
MPTSYPTPSPKNSSAELVKKRIQDKSPNRPHWTQIRLSDETEALCAVLDHFNSLHFSDRDRLAKKIDPNHGRLIHQPEHKGGFDAA
>NZ_CP042425.1|WP_149111458.1|4387063_4387411_+|hypothetical-protein
MSNTERHMTDEEAVSYQFFLNGQLKNCVEAMVACVVRYQQECPDGLLAKHTEQNWIDLEAQLHDAVTDMLSEDISRISTTLTDECRFIGQWKSRWQEQFEVRRSAELAANRLNAA

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Crispr_ID: NZ_CP042425_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_11

6741514-6741605

Orphan

Consensus_repeat	Method
CACCGCAGACGTTTGCGGTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_11

>merge|NZ_CP042425|11|6741514-6741605|CRISPRCasFinder
CACCGCAGACGTTTGCGGTGGGGGCTGGTGAAAGGGTCTCGGTGATGGCGATACCATTCCCCGGTGGAACACCGCAGACGTCTGCGGTGGGG

>NZ_CP042425|11|10|6741514-6741605|CRISPRCasFinder
CACCGCAGACGTTTGCGGTGGGG	GCTGGTGAAAGGGTCTCGGTGATGGCGATACCATTCCCCGGTGGAA
CACCGCAGACGTCTGCGGTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_168219257.1\|6734757_6735147_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113305.1\|6744637_6744955_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP042425.1\|WP_149113302.1\|6742903_6743674_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113293.1\|6730646_6732071_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NZ_CP042425.1\|WP_149113307.1\|6745757_6747095_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214947
NZ_CP042425.1\|WP_149113304.1\|6744159_6744486_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113308.1\|6747183_6747507_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219259.1\|6747555_6747708_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219071.1\|6736737_6738003_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP042425.1\|WP_149113300.1\|6741715_6741919_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219256.1\|6732412_6734758_-\|DUF3987-domain-containing-protein	unknown	unknown	gnl\|CDD\|379041
NZ_CP042425.1\|WP_149113303.1\|6743712_6744114_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366911
NZ_CP042425.1\|WP_149113294.1\|6732145_6732397_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP042425.1\|WP_149113297.1\|6740065_6740617_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367983
NZ_CP042425.1\|WP_149113296.1\|6735149_6735713_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113306.1\|6745098_6745761_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113298.1\|6740676_6741087_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168218808.1\|6738290_6739419_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP042425.1\|WP_168219258.1\|6735811_6735967_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113301.1\|6741915_6742782_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_168219256.1\|6732412_6734758_-\|DUF3987-domain-containing-protein	gnl\|CDD\|379041	pfam13148, DUF3987, Protein of unknown function (DUF3987). A family of uncharacterized proteins found by clustering human gut metagenomic sequences.	2.44007e-57
NZ_CP042425.1\|WP_149113303.1\|6743712_6744114_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|366911	pfam02082, Rrf2, Transcriptional regulator. This family is related to pfam001022 and other transcription regulation families (personal obs: Yeats C).	0.000196171
NZ_CP042425.1\|WP_149113294.1\|6732145_6732397_-\|hypothetical-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.50938e-05
NZ_CP042425.1\|WP_149113297.1\|6740065_6740617_+\|hypothetical-protein	gnl\|CDD\|367983	pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.	0.000484705
NZ_CP042425.1\|WP_168218808.1\|6738290_6739419_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.65881e-38
NZ_CP042425.1\|WP_149113305.1\|6744637_6744955_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.59713e-15
NZ_CP042425.1\|WP_149113293.1\|6730646_6732071_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	1.6879e-20
NZ_CP042425.1\|WP_149113307.1\|6745757_6747095_+\|hypothetical-protein	gnl\|CDD\|214947	smart00974, T5orf172, This entry represents the putative helicase A859L.	1.20398e-19
NZ_CP042425.1\|WP_168219071.1\|6736737_6738003_+\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.01529e-22

>NZ_CP042425.1|WP_149113298.1|6740676_6741087_-|hypothetical-protein
MRPPPIELSAVSAAGATFAGVPVAAVRLVLANGNVLRLRLAATAHPGVVTAVTGAPAEGRPEPFCATECSRDLLGVLRASDGPLVLSAILARLESRNQLHGESTVKRALAAMVRAGVLANPGHRVGYSIAGVGQSE
>NZ_CP042425.1|WP_149113297.1|6740065_6740617_+|hypothetical-protein
MCRPKPAGAGVPPVDLLALWPWVEKIALRVAARYLLWGEAALDDLISAGYVRALEKIPHFRPDDPKAAADPNGAFRGWAYRDVMTYVQREAARLRGGGTFRSPRREPGRDPVIAKPISDFEGGRQGERDEPFRAEDVAEEFRDQLVTEPLPRTPEGDDCWWEGMLEPHHHLQKPFDLSEFHDE
>NZ_CP042425.1|WP_168218808.1|6738290_6739419_+|IS3-family-transposase
MTAKRKTHTAAFKAQVALAAVKGDKTVNELAAHFGVHPTLIHGWKKQLLAGAEAVFAAGAKAVAPGDDQTPALYEQIGRLKVELDWVKKKAATFSVDDLRPLIDPGHADLSVRRQCQLVGLGRATYYRGPAEESADNLALMRRIDEQYTACPFYGSRRIARWLARNGHPANRKRVQRLLRVMGLEAIHPKPKLSAGRGHPVYPYLLRGVPIDRVGQVWSADITYLPLPGGFMYLAATIDWYSRYVVAWRLSNTLDGAFCRDMLDEALAAGTPEVFNTDQGVQFTAGAWVERVEAAGARVSMDGRGRCLDNVFVERLWRTVKYEDVFLRGYETVTELERGLKAYFTFYNEARLHQSLGYKTPAEVYRAGRSKEPAKE
>NZ_CP042425.1|WP_168219071.1|6736737_6738003_+|IS110-family-transposase
MRFIGLDLHKKMLVVCALDDRGQVLFRETVECRREALEAFARVKLQATDRLAAEATTNTWAVADILRPFVAAVTVGNPLQIKAIAQAKVKTDKIDAEVLAHLLRCDYLPTVWTPDAATQKLRQLTTVRGGVIADRTRIKNRVQSLLAQLLVVPPVKVVFCRKGVAWLRAVALPAEVRSAVDLYLRLYDAVDAELKKIDDQLMGMAYDDGRAKLLMTLPGIAHGVALSLLAALGDIGRFPDGDHAASYLGLTPRLRQSAGKRHYGGITKAGCPQTRAMLVQAVQAASDHPGPIGAFFRRLRKKKKYNVAVIATARKLVTIAYLMLKHNEPYRYAKLDVVKNKLTDCRRKAGSASRSEHESDGSRLNDLYREHGLPACQPPAAWSAGERRGHADPAVTAFAEEAHGPPAKKSRSKRRASTTSE
>NZ_CP042425.1|WP_168219258.1|6735811_6735967_-|hypothetical-protein
MIPDSLRAHVRTGNYVPIVAGTVVVIPVPNKPADPRMLLRLAPSHGRHEAR
>NZ_CP042425.1|WP_149113296.1|6735149_6735713_-|hypothetical-protein
MIVPAPKSSAAPVYWDEYYRIAAISELIAAVDPERPGPRPMAFAAVYQEQIEFRVLHELLQARAIIASAEHALPGIVERVEVLADRIAAEDAEAEDVADVDPDRVVQPPSEPVAAATDEPPPLTVEIKQAFRKLAARRGDARKRFLALMLDFLDGGDRFLRLGEEAEREEAVRRNQRPTNRLKKGGC
>NZ_CP042425.1|WP_168219257.1|6734757_6735147_-|hypothetical-protein
MIATRPEPLTSADAPLRPQDRWPTRQITLLQKDLADAERSHNAARIAAADAHLEAELEYLAELGMTLLHYATLRRPITTTSILMLPLDGVRHDLLGLAARVEELEAIVARLGAAVEGLAANRHPAREVS
>NZ_CP042425.1|WP_168219256.1|6732412_6734758_-|DUF3987-domain-containing-protein
MAAEISFRASPANPCPVCGGGSKGCSAVADGLHFCRGTPRDGWRRVGQPDDNGFTHYRRADDRGHDRDRPATVPLSSAATPQQLRNLADALKLPAAALAALPIGWDGEAWTVPEVDAKGATVGIHRRFPNGKKYMQKGGHRGLVLPRGWREKSGPVLVVEGMSDALAGTYAGLACVGRPNNAGGGNLLAELLRGLPIDRAIVVVGENDQKADGLWPGKAGAEALAGRLANDLARPIVVAIPPGPFKDVRDWLTAKIAKGVRWPDAGQELCRLLTDGGTVTEAPANPTAVTKPGVQAPAVTVPEYRPFPTHCLPDRVQNFAETVARATNTDPSYAALPILSVLGAAVGTTRVVCPKAGWRIFPAVWAITIGRSASGKSPPQIIVNNAVQLLEDDLEAENDAARGDHERRLEGFRRQRRESEDAVRPAEPREARFRVGDVTVESLAGILADNPRGCWLWCDEAAGWLTSFTRYKSGGGGDSDRPRWLSLFDSGALTADRKTGTRRTVRVRNSLVCVCGGIQPSILKSLMTPDNVGSGLFARILLAYPPERLQRWTEVGVADDMVEAFAGLLRELRGFGFDTLRGRPVPAVNHLSADAKALFVAYYDRNREAAHTGTDGEAASLLKLESYAVRFAHLRHLCRHTAGGDGQPIDALDMHAGIELAEWFADELFRIQAALQETEHERAGRCLVDLVHRRGGAMTARDLQKHNARKYRTAAHAEAALQSLVDGGLGEWLKETAANGQTVRRFRAAPSADGRQTPSDAPAENVDSPGKSAKVSERLSV
>NZ_CP042425.1|WP_149113294.1|6732145_6732397_-|hypothetical-protein
MKSEGFESPPAAASLAVDAKRLGELLSGVSERTIRTWDAAGYIPEPVRVGGKVLWSVAEVRAWLAAGSPDRVTWAACKAVRPS
>NZ_CP042425.1|WP_149113293.1|6730646_6732071_-|tyrosine-type-recombinase/integrase
MGSLLHPTYTAPIPKNAERVKVKGRPCVRFASRGKVRTLPLSEDGTRVVKQAAKWYGQYVDADGTTQRKPLARDKEAARQLLAEIEKKVERRRSGLVDVTDEHARRPLLEHLDDYEAILRAKGDTDRHIVKTVYRIRSVLVGCRFAFPGEVDSSKVAAWLSALREGSTPAAVPDWPAFTPAEAAEVLGITTHTLSIAVKRHGLAATGKSRARRLPRETVTALAAIAAEGVGPATQNHYLRALRGFFRWLAKGRRIALNPLDGLELVCEEVDIRHARRELDLEELRTIFAATRGSNRTFRGLDGVDRHVVYALAVTTGFRTAALASLTADSIDLAARTVTLSARANKSRKAKVQPLTPDAAELLAEYLRARPRRGRLWPGSWAGRSADMLKADLEEAGIPYVVEGRDGTPLHADFHALRHSFLTIGGRSGIDLRTLQELAGHSTPVLTARYMHVGKGIWPAPSTGCPVRLHCRLH
>NZ_CP042425.1|WP_149113300.1|6741715_6741919_-|hypothetical-protein
MTADGPPDPVATLLLASLSARAVEFLAAVAATAAGGNRPGHGVRVEVSAHGVTVTVAVDPVGGLPSR
>NZ_CP042425.1|WP_149113301.1|6741915_6742782_-|hypothetical-protein
MKTTKTKTRTLVETNGFIPHGEQCCADPACGARTAVTAVKRTYCTGYGSDCPPVDHPDDTIPVAFADGRTGDVLSDRVDHFLAAVASESGDWGPYRGVGPLGAAAVVGVELRAAASDECRRMAEAQRAVRDVAAIVGEFAGEHRRFCSCSLCAFWSTGSGDRGRAARRALRLARELVKTSAAFLEAVREAAPDHRAFKYEHIIQYAPWTDPFNQGVPTAPDLVAAARERLAVSRAAVHTDPGQAGRYARALGIPYVGRFPADPGEADDDAMPDAIAERLAGGVIGEGL
>NZ_CP042425.1|WP_149113302.1|6742903_6743674_-|hypothetical-protein
MIRSLDFFHGYARVTFHDGSAVDVKCKCWGPAASDAEARHVAAVVALQARAAHSPEMALIARLDKLLNEASEVCFRLYETIRSGNSDLWDLWRLLMVDPPPGVPKTPRKIRLRPPTREQRRTDPVGQRRSIPHQVATLQGRLNHLWLNLQGELLERVTFLHVVSAAKLSHAPEYLSGQRVTARADTTLGDVTDYYPLGATLPPLPPVPTEPTKPTKPTRPKSRLRVIPPYRFNLPPARKGHRELLPPANGKLRPRE
>NZ_CP042425.1|WP_149113303.1|6743712_6744114_-|Rrf2-family-transcriptional-regulator
MTASAPIDLAALWHAGATLGGLPVASVRVTLASGAVVHVRLAAADLAGPVPAAGLSPPPTFRPNPCSRDVLAILEAAEGPLVLPDIRQRLENREQLHGESTVRKVLAAMVRAGILTNPGHRAGYSLARPPAAS
>NZ_CP042425.1|WP_149113304.1|6744159_6744486_-|hypothetical-protein
MCLPVAGSLPASKTHKAGRRWALLPSADATSPSLGTLTIVQSKRDTVSYGVAVEGGQVLFCKLSDGEVYGVTLDRSGRPVCCTCDGFHFVKRCKHLDTVKELIADGVL
>NZ_CP042425.1|WP_149113305.1|6744637_6744955_+|helix-turn-helix-domain-containing-protein
MSLGEAISALRKDLGLSQKDLAAKCGISQPMISALESGKETDLRASTLVAIAVALGVDCNHFAQFLKLPSDEAVSQPLPTPKRGRPKKADAPPQTPAPPARRKKG
>NZ_CP042425.1|WP_149113306.1|6745098_6745761_+|hypothetical-protein
MATKAELESERQRCHAIALRAIAAERAFEYGHAIGIALESLPHLDAAMQFEKRYLKIENPPVPSVEVIFRCAPPLFRYDALDVVDQFLDRQKKVEKNAAVDLRSELAATRSRMVLANRMWAEIENGQYDAEADRRHPAADENEIRNAWDRLGLLEAAHAGGRSVWLFRTRLDEDVQARCFNCGRRVQGRKLRFLEVGKCPRCETVAHFAILDRPVKEQRP
>NZ_CP042425.1|WP_149113307.1|6745757_6747095_+|hypothetical-protein
MSTILLVLFGFALGMAIIFFPMMDRQKRIDERERKADRRAEDLDADERQLDGEERRLREEREAFAEEVRRDRASLAEQARALQLAQADFQRRSVSYDEHVRENQILKADIRNTATSVARQKFEQQQLRDSQARVESLANQVAHRYLSETQTWVSRSLTETNYVTNKKRLQDAITRCRAMGVIVTTAQEAEYMARLQAEYEDAVRVAFEKEAQAQARQRFREDQQRVREQQQAEAEREKAEVEKRAVEARLAKAMEEALGKQSDVMKQQHADDIARIQKQLAEAQQKLDERTEKAISLAQLTKVGNVYVISNIGSFGEGVFKIGMTRRAEPMERVIELGDASVPFPFDVHMMIRTDNAPDLEHKLHQRFRRSQVNKVNPRKEFFRLSLDDVVKAVQELHGEVVYTVTPDATQYRESLSIRPEDQEVIERVHERERRRMPATAFEEE
>NZ_CP042425.1|WP_149113308.1|6747183_6747507_+|hypothetical-protein
MIELLLLYRLCKRIGQIAREKGRRAVGYQFMTIAFWFGGELLTAFVLAALLFVRGGEEMLHEYELLVYVAALLGAGLGAWTAFEIAKRLPHLADAVEAIDEDGISQR
>NZ_CP042425.1|WP_168219259.1|6747555_6747708_+|hypothetical-protein
MRTKVFRTLAGVVAALFALVFVAGDVGRMGRAEVALLAVIACLFALYAAF

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Crispr_ID: NZ_CP042425_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_12

6924982-6925105

Orphan

Consensus_repeat	Method
CGTGTAACAGTGCCCGGCCGAGAACTTTTCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_12

>merge|NZ_CP042425|12|6924982-6925105|CRISPRCasFinder
CGTGTAACAGTGCCCGGCCGAGAACTTTTCTCCTTCACCGCTTGATTCCCGTTCCACCAGTTTCTTTATTCCAGCGGTTGGTGGCCGGCGACGTGTAACAGTGCCCCGCCGAGAACTTTTCTCC

>NZ_CP042425|12|11|6924982-6925105|CRISPRCasFinder
CGTGTAACAGTGCCCGGCCGAGAACTTTTCTCC	TTCACCGCTTGATTCCCGTTCCACCAGTTTCTTTATTCCAGCGGTTGGTGGCCGGCGA
CGTGTAACAGTGCCCCGCCGAGAACTTTTCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149113462.1\|6925723_6926137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113452.1\|6916482_6917499_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113464.1\|6926762_6927713_+\|acyl-CoA-desaturase	unknown	unknown	gnl\|CDD\|224316
NZ_CP042425.1\|WP_149113458.1\|6922214_6922592_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219071.1\|6918665_6919931_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP042425.1\|WP_149113456.1\|6921282_6921675_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219283.1\|6926118_6926508_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176853
NZ_CP042425.1\|WP_149113465.1\|6927824_6928175_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113453.1\|6917670_6917889_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239589
NZ_CP042425.1\|WP_149113457.1\|6921671_6921950_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113467.1\|6928986_6929424_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222832
NZ_CP042425.1\|WP_168219284.1\|6930124_6932899_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853
NZ_CP042425.1\|WP_149113461.1\|6925162_6925708_+\|discoidin-domain-containing-protein	unknown	unknown	gnl\|CDD\|366285
NZ_CP042425.1\|WP_149113459.1\|6922631_6922991_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219285.1\|6933099_6934353_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP042425.1\|WP_149113468.1\|6929590_6929896_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113466.1\|6928202_6928928_-\|YHS-domain-containing-protein	unknown	unknown	gnl\|CDD\|309878
NZ_CP042425.1\|WP_149113455.1\|6920349_6920766_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219281.1\|6920878_6921016_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113454.1\|6917917_6918130_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149113467.1\|6928986_6929424_-\|hypothetical-protein	gnl\|CDD\|222832	PHA01748, PHA01748, hypothetical protein.	0.0010876
NZ_CP042425.1\|WP_149113464.1\|6926762_6927713_+\|acyl-CoA-desaturase	gnl\|CDD\|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	7.97523e-73
NZ_CP042425.1\|WP_149113461.1\|6925162_6925708_+\|discoidin-domain-containing-protein	gnl\|CDD\|366285	pfam00754, F5_F8_type_C, F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.	7.53256e-10
NZ_CP042425.1\|WP_168219283.1\|6926118_6926508_-\|hypothetical-protein	gnl\|CDD\|176853	cd05018, CoxG, Carbon monoxide dehydrogenase subunit G (CoxG). CoxG has been shown, in Oligotropha carboxidovorans, to anchor the carbon monoxide (CO) dehydrogenase to the cytoplasmic membrane. The gene encoding CoxG is part of the Cox cluster (coxBCMSLDEFGHIK) located on a low-copy-number, circular, megaplasmid pHCG3. This cluster includes genes encoding subunits of CO dehydrogenase and several accessory components involved in the utilization of CO. This family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	2.94095e-12
NZ_CP042425.1\|WP_168219285.1\|6933099_6934353_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.90128e-112
NZ_CP042425.1\|WP_149113466.1\|6928202_6928928_-\|YHS-domain-containing-protein	gnl\|CDD\|309878	pfam04945, YHS, YHS domain. This short presumed domain is about 50 amino acid residues long. It often contains two cysteines that may be functionally important. This domain is found in copper transporting ATPases, some phenol hydroxylases and in a set of uncharacterized membrane proteins. This domain is named after three of the most conserved amino acids it contains. The domain may be metal binding, possibly copper ions. This domain is duplicated in some copper transporting ATPases.	8.03827e-06
NZ_CP042425.1\|WP_168219071.1\|6918665_6919931_-\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.01529e-22
NZ_CP042425.1\|WP_168219284.1\|6930124_6932899_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	3.47298e-39
NZ_CP042425.1\|WP_149113453.1\|6917670_6917889_-\|hypothetical-protein	gnl\|CDD\|239589	cd03512, Alkane-hydroxylase, Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes in Pseudomonas oleovorans encode conversion of alkanes to acyl CoA. The alkane omega-hydroxylase (AlkB) system is responsible for the initial oxidation of inactivated alkanes. It is a three-component system comprising a soluble NADH-rubredoxin reductase (AlkT), a soluble rubredoxin (AlkG), and the integral membrane oxygenase (AlkB). AlkB utilizes the oxygen rebound mechanism to hydroxylate alkanes. This mechanism involves homolytic cleavage of the C-H bond by an electrophilic metal-oxo intermediate to generate a substrate-based radical. As with other members of this superfamily, this domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. The active site structure of AlkB is not known, however, spectroscopic and genetic evidence points to a nitrogen-rich coordination environment located in the cytoplasm with as many as eight histidines coordinating the two iron ions and a carboxylate residue bridging the two metals. Like all other members of this superfamily, there are eight conserved histidines seen in the histidine cluster motifs: HXXXH, HXXXHH, and HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homolog, stearoyl CoA desaturase. Also included in this CD are terminal alkane hydroxylases (AlkM), xylene monooxygenase hydroxylases (XylM), p-cymene monooxygenase hydroxylases (CymAa), and other related proteins.	0.000354322

>NZ_CP042425.1|WP_149113459.1|6922631_6922991_-|hypothetical-protein
MNDREWAYLLRALPSQAGTLIVCLTAVVFAVFKMGRHPKPAGLTLAGAVMTIAATVVPTVFHAIAYTNPARGSKQHIEDLNLAGDVGRVAYQVKALGMALIVAAVFSGRQRQDRPRGYE
>NZ_CP042425.1|WP_149113458.1|6922214_6922592_-|hypothetical-protein
MNEPRPSCDRGRCRNQFQHSAPCLTNSPRHLNTAAVPLAAPLATHTPIEIGQLHALYGNGCHHLPIFPPDAAEGYAGQFHQFPSFDFRGWVDGVRVVGFLYGDRVRRGRRAEEGRPGEAAGRGRT
>NZ_CP042425.1|WP_149113457.1|6921671_6921950_+|hypothetical-protein
MNEVRKRLTASRQYASEKFVIGEGGGFDLNAEFVHGWKKANGYPTAPPKKPTAETPSVPEPIAYRMQSVEPSANGTGDDKLCTCNGETNGTH
>NZ_CP042425.1|WP_149113456.1|6921282_6921675_+|hypothetical-protein
MVRDRHEPARGRCIVATELRAAQSCECRRMGNVERVVRDVTALAGEFRRAHKRFCGCAVWAVCAVWATARPAKQKAAVKVMKATDALVAAAQELIKAIAAAAPDAYRREPFVSNMWSPWDQPAHFGPPNR
>NZ_CP042425.1|WP_168219281.1|6920878_6921016_-|hypothetical-protein
MPRLRSSLSSSTLNGFFAAAGVSVVSALSSISVVASVVVVISKLL
>NZ_CP042425.1|WP_149113455.1|6920349_6920766_+|hypothetical-protein
MSATANTAGNKPAVIPPLGTLHIVQSRGVKSYTLAIVREPNGRPVVVFTRKAPSADTHRVTLADTWKAGVCTFAGHHFAHHCAHVDAVLSMLAAGVLPDPAEWLAERERATLMATLAGATKSLTAAGLTVGPLTPITV
>NZ_CP042425.1|WP_168219071.1|6918665_6919931_-|IS110-family-transposase
MRFIGLDLHKKMLVVCALDDRGQVLFRETVECRREALEAFARVKLQATDRLAAEATTNTWAVADILRPFVAAVTVGNPLQIKAIAQAKVKTDKIDAEVLAHLLRCDYLPTVWTPDAATQKLRQLTTVRGGVIADRTRIKNRVQSLLAQLLVVPPVKVVFCRKGVAWLRAVALPAEVRSAVDLYLRLYDAVDAELKKIDDQLMGMAYDDGRAKLLMTLPGIAHGVALSLLAALGDIGRFPDGDHAASYLGLTPRLRQSAGKRHYGGITKAGCPQTRAMLVQAVQAASDHPGPIGAFFRRLRKKKKYNVAVIATARKLVTIAYLMLKHNEPYRYAKLDVVKNKLTDCRRKAGSASRSEHESDGSRLNDLYREHGLPACQPPAAWSAGERRGHADPAVTAFAEEAHGPPAKKSRSKRRASTTSE
>NZ_CP042425.1|WP_149113454.1|6917917_6918130_-|hypothetical-protein
MLSVMAKRKQSTKDDDSDGGGVLFIRLPEAVREAFERMLAEDPLRPKKQDIGLRALVAHLELNGYWPPKK
>NZ_CP042425.1|WP_149113453.1|6917670_6917889_-|hypothetical-protein
MEMTPKQAKRWATTRAKGRSRFIWFNGVLVWGLTMAVVWPVAMAAVQGWDRLPLLMACAIVGFPIAGYYFGV
>NZ_CP042425.1|WP_149113452.1|6916482_6917499_+|hypothetical-protein
MKPLPKLPEYPKQGFPGEGNLTGDEEKVTRYAGRFPAIVELCNNHRITHFTAATEAVRERIQLLREGLAILKDETKEEQKLPELIDNDVKLNAVGFMVAAALKDMRTVNFCYHQSLNEVLTRDLAHAGAWKDGFVTMRAAAKASDKIAAAMIEKVVAYDSMATTLLNELRVRAKIIKGDKAVMTQIKVVFEKGPQMEVNAEEALKGVAKSVEEFKKLIAEWSENQKKPKDDNQTTKTEELKKKMDDRLKKLTAASERFRTPMVSLRTLGLSLKPMGEKLGSILKKNKVQTMIDKLAKSYSGLLKKVDDLQKTIDGFRNTSTLPENIKNHLPKQWDKTQ
>NZ_CP042425.1|WP_149113461.1|6925162_6925708_+|discoidin-domain-containing-protein
MPRFLIGLTTLALIFGVSLAAPVPKTAKPVVGETNENGLITTHREKLQLAASSEWANWPVAHAFDGKAETSWYSNNGDAPQNGKTPTITVTFPEDVRMKRVTVLGNRDPQYPTGYFVLEGKFELLDKDDKVLETHEMKAAGEKHDFDWVLKKLTTVRAVRFTMTKDEGQTGCVGIGEFQVE
>NZ_CP042425.1|WP_149113462.1|6925723_6926137_+|hypothetical-protein
MLRLRRILGYLWASPNTLLGLLVLPMALATGGAVQVVRGVVEIHGGFARWFLARGLPTAIPIFGPAAALTLGHVVLGQDRECLDKSRDHEHVHVRQYERWGPFFLPAYFFASFLAWRRGQDPYFDNRFEREAYGTAS
>NZ_CP042425.1|WP_168219283.1|6926118_6926508_-|hypothetical-protein
MSDAAFLAACVPDAVVRSASADAAEWQAKARLGFATATLESQLAITGRTPGESVTFTLANRTAGAGLGVMTKLSFDDAAGGTNVDWTAEITSRSGLLKLAPSSLLQSQVQSLLSDLWQSVRTKLQDAVP
>NZ_CP042425.1|WP_149113464.1|6926762_6927713_+|acyl-CoA-desaturase
MPRPTLPAAPQPAAFKRAVQTIFAWVNVLPFLAIHVACVSVFFVEFHWWAVALFAVTYSLRVWGLTAGFHRYFAHRAYKTSRWFQFVIATCGSAALQKGPMWWAGEHRQHHRHSDQDGDPHSPIKKSVFWAHIGWVIDRNNGDTDWHEMKDWTKYPELAWLDRFHWVPPALLGFACWYFGGATGLVWGFVLSTVAVYHVTFCVNSVCHLFGYRRFETTDHSRNNWLIALLTFGEGWHNNHHHYQSSARQGFAWYEVDVSYYSLKMLSWFGLVWDVREPTARAKQKNLIGAKPAAQVVQGQLPTVEQESVKETPVAG
>NZ_CP042425.1|WP_149113465.1|6927824_6928175_-|hypothetical-protein
MTADRKLRLAGFALILVGTIAAIINGRVNITKNNRMIALSENRPTSELPSSEYHTRLQEDLSERWRAAENASAWQTQLVIISYITMLLIGMLVLNAARSLPTVSSPSALREGSPIA
>NZ_CP042425.1|WP_149113466.1|6928202_6928928_-|YHS-domain-containing-protein
MGSLTLALACLFVTPAADPAPANAKEALKPFNLFVGKWKGTGIPDTAGGKPKEFWSETVAWEWHFKGDDVWLTATFDKSPHYKTGDLRYLADKKAYTFEVTTTDKKSLTFQGPLTPGKGKEQVLTLDRTDDTAKTTERLVFTLLHSNRYLYRLDSKPTAAASFARQFQVGETKEGESFADVPKGPECVVSGGTGTMRVTHGGKTYYVCCSGCRDAFKDEPEKYIKEYEAKLKAEAEKKGKK
>NZ_CP042425.1|WP_149113467.1|6928986_6929424_-|hypothetical-protein
MARKPQKTSKSQIVAFKVEEELAEFLDNLPNKSDFIRKAILAQFGMTCPLCVGTGVVARGVHDHFKPVIEHQNQKPCEKCKTPVSFPMNADGLSGGEKKRIEQFLHGGPLYCLKCYPTIPPCDDCGWHVPMEKVAEHFKRQHTHA
>NZ_CP042425.1|WP_149113468.1|6929590_6929896_-|hypothetical-protein
MRKFALALAALACSFGLLIAGEVAFVKYDADKKELTVKDGDKEKVLKVTDKTTFKRGDKDVPNDKGIESLGKMKEGKGKLEVTVEKDTVTEIKMVGGKKKN
>NZ_CP042425.1|WP_168219284.1|6930124_6932899_+|ABC-transporter-substrate-binding-protein
MNNTRSLPRHVRPFLLSFGLLLLTVVVGINGQGQIVPKKTDKKGEKESPAVPGGTGAYAEVEDPKAKKVRESIPIDDEAPVVFLPKGAYYVRIEDLARAAADTPSPPLRALLLRYVVAFDRITDFQDKAQRVTPIPAFRLGKIPPVFGVFDLDDRNQPAALRRMESTKVRKIEHYEELIVEEAERLVNAKLLEPPGVERKDRVEAAEQLLAGALLFHDAARDQSKRKGIGWEQVRAKVADTLSAVRLTRLKLASERKDWALVRSLGSRMTSLYPNNLKLLEEVFTARLAEALLAATESEKPAELENARDLLSEFESRFPGSKSETAESIREALKEKAKNLFEQASVALRQNDQKRAQQLIRTVETIDPGHAGLRDLQGQLTGAYSVLYVGARHLPERMTPLTARFPSERQAVDLIFEPLLEALPDDSYGVKYRPVLANAMPTAAGLSRDFTLVKTAEWAGLGREYLDATDVAGTLKAVRDKYRHTWVGEYVDWMPDPVRVEDHTRLRINFASGHPFPLAMMTTKVLPARWLTAENKQLDDLVFALKPVGTGPFRFVGKGQPTDGPTEVVFAANPTFARRAGRIGQPFIKEVHFVDLAKVADPAALFRSGQLHFLPDVPTGELAKFTAPAAKLKGQVDVVTTESNRRIYMLAINHQRPELNSVALRRGLAHAIDREEILDKVYRAGFSQFHKALVGPFPPNSWPIPKVAGSVPPPLFDSSLAQAKMSEYAVRGGEKTLTLLYSTDDARSRFACEMVRKQIETATATAVSIKIALEGLPAVVFHKRVYEDRDFELAYVPFEYRDDWYPYGLGFLLDPEAQSQGGRNFMRYPPRTVSPSREDKLLGQQLEEIRHHADFTGKLSPQAQRLQLRFVEAMPFIPLWQLDRHMVVSTKLKFYLDDTGEALNPKWLAPDHAFAGVARWKLQD
>NZ_CP042425.1|WP_168219285.1|6933099_6934353_+|serine/threonine-protein-kinase
MLTRLRTTADLPDNSGECAEQLIQQGVLTRFQSKQLLAGKFRGFVLGPYRLLDQIGKGGMGTVYLGEHATLKRRVAVKVLARELAENKISVERFLREARSASALTHGNIVRVHHVGQAVGTHYIVMEYVDGVTLEQVVDRKGPFSATEAAQIAVQAAAGLQHAHERGFVHRDIKPENLMITKNGTVKVLDMGLTKSIQSSSDNLTGVLNSKAILGTIDYLSPEQGLQSDVDARSDIYSLGATLFTLLTGHSPYDGVPAQQKLMQHQFGKVPLLSEFRSDLPEGLTAVVAKMMAKQPGERFQTVAEVADALMPWTADGGRSANITLPSRVMANPNAANQSQTPTIRDAAGKTSSDVPPQPAQPPAAPKVKGDFEELFVVGSPRPVVARPGIPPKVWGLLVILGVSIGLGAAIAAFLLG

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Crispr_ID: NZ_CP042425_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_13

7077338-7077446

Orphan

Consensus_repeat	Method
CCACGCAAGCCACTGTTCCTCCGTCATCGCCCACCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_13

>merge|NZ_CP042425|13|7077338-7077446|CRISPRCasFinder
CCACGCAAGCCACTGTTCCTCCGTCATCGCCCACCCCCACCCTCTTGGGGGTCACGGGGTAACGATGGGCACCACGCAAGCCACTGTTCCTCCGTCATCGCCCACCCCC

>NZ_CP042425|13|12|7077338-7077446|CRISPRCasFinder
CCACGCAAGCCACTGTTCCTCCGTCATCGCCCACCCCC	ACCCTCTTGGGGGTCACGGGGTAACGATGGGCA
CCACGCAAGCCACTGTTCCTCCGTCATCGCCCACCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149113591.1\|7080704_7080950_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370725
NZ_CP042425.1\|WP_149113585.1\|7078151_7078367_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113589.1\|7079868_7080255_-\|response-regulator	unknown	unknown	gnl\|CDD\|381118
NZ_CP042425.1\|WP_149110579.1\|7074432_7075809_+\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP042425.1\|WP_149113578.1\|7067163_7067472_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP042425.1\|WP_168219298.1\|7073102_7074035_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP042425.1\|WP_149113580.1\|7068044_7068845_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP042425.1\|WP_149113594.1\|7083954_7084791_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149110580.1\|7075937_7076546_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113579.1\|7067620_7067968_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149115663.1\|7076701_7076947_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113582.1\|7071585_7072113_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113583.1\|7072147_7072534_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113592.1\|7081547_7082852_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP042425.1\|WP_149113581.1\|7068979_7071502_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219299.1\|7079221_7079722_-\|DUF4142-domain-containing-protein	unknown	unknown	gnl\|CDD\|379301
NZ_CP042425.1\|WP_149113590.1\|7080348_7080528_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113586.1\|7078389_7078671_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113587.1\|7078768_7079110_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113593.1\|7083124_7083472_+\|DUF1016-family-protein	unknown	unknown	gnl\|CDD\|377634

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149113591.1\|7080704_7080950_-\|hypothetical-protein	gnl\|CDD\|370725	pfam09855, zinc_ribbon_13, Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082). This domain, found in various hypothetical prokaryotic proteins, as well as some Zn-ribbon nucleic-acid-binding proteins has no known function.	5.32798e-08
NZ_CP042425.1\|WP_149113580.1\|7068044_7068845_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	1.68416e-08
NZ_CP042425.1\|WP_149113592.1\|7081547_7082852_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.06015e-10
NZ_CP042425.1\|WP_149113589.1\|7079868_7080255_-\|response-regulator	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.03858e-35
NZ_CP042425.1\|WP_149110579.1\|7074432_7075809_+\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.68907e-38
NZ_CP042425.1\|WP_149113578.1\|7067163_7067472_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.34225e-10
NZ_CP042425.1\|WP_168219298.1\|7073102_7074035_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	4.5308e-43
NZ_CP042425.1\|WP_168219299.1\|7079221_7079722_-\|DUF4142-domain-containing-protein	gnl\|CDD\|379301	pfam13628, DUF4142, Domain of unknown function (DUF4142). This is a bacterial family of unknown function.	3.62978e-39
NZ_CP042425.1\|WP_149113593.1\|7083124_7083472_+\|DUF1016-family-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	1.93398e-12

>NZ_CP042425.1|WP_149115663.1|7076701_7076947_-|hypothetical-protein
MLRDIFGNPFRPVTFSPAWLTPTAVGLAQAIYEDRAFDRLPILADALQDAGCEDEAILGHCRGDGPHVRGCWVVDGVLGKG
>NZ_CP042425.1|WP_149110580.1|7075937_7076546_+|hypothetical-protein
MAAKKNQERSGAGMDKEAVAVESVRQFVWSGFYDADGIVEMIDEAVLSPGELDHGWLRARIEEEFRKKRADELAWPAITDCDRLDQVFELLEQQGILALQNAGYTQDNGLDDVTQFYHEAGGEQSGIGGYCFYHGQDLERVMENGDLHLTYGDIRGDDEKGIEIGRRIKRALETAGFTVVWDEAIKTRLLVKGIKWQRRLSE
>NZ_CP042425.1|WP_149110579.1|7074432_7075809_+|IS66-family-transposase
MDEPACPRCRDLLKRVAELEAQVAELTRKLEEAVRAGKRQAAPFRKGPPKPDPKPPGRKSGDAHGTHGHRPPPPPEQVAECHEAHLPDACPHCRGRLVETGTADQYQTEIPRTPLIRKFRVHVGHCEGCGKRTQGRHPLQTSDALGAAASQVGPDAQAAAAVLHTQMGLSHGKVASAFRTLFGITLTRGASARIDLRAAARLEPDYTLILDDVRSSEQIAADETGWRVGGHPAWLHAWVGDRATAYGIDSKRSADALERVIGADWSGVLSHDGFASYERFEGAIHQQCVAHVLRRARDLLATATRGAVRFPRQVIALFTEAIHWRNGYVPGTWTDNQLDAHRVSFDDRLLDLVRRPRAVPEYATLARHLRNHFEQWFAFVFDPRIEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAQAQGVLMSVFETCRRQTLSVVDHISQTLRWFGNRLLTRPPLFG
>NZ_CP042425.1|WP_168219298.1|7073102_7074035_-|DUF1559-domain-containing-protein
MVVIAIIAILIGLLLPAVQKVREAAARAKCTNNLKQIGIALHAYHATNSRLPAGTTTTSFMGPNTFLLPYLEQDNIFALIVPAPAITTVGTTTTANAWTKNKPTVFLCPSDTEQGDSAAMGYSNYHYNGGSWGKLNGWDGVFGMGQVSNNSPAATVAKGFTFLGIADGTSNTAAAAESCNFPQSGPNNKLGDCFEAGAVTDTTLAAARTTLLAKNWTTATLAGSTWRGKGYAWDEGSMWRGLYNHLLPPNSPCWRPGDYGIMVSPASSRHSGGANVLMADGAVRFVTETIDPDTWTAAGTRQGAEALTLP
>NZ_CP042425.1|WP_149113583.1|7072147_7072534_+|hypothetical-protein
MTPTIDKPFGDLRPQTWADVELIVAFLELMTRGNPIRGDHADLWLRAVKRGKTEDVYLAAHFAADEVAAHPLAAHIRQAMAVSVDFLHAPKMVAATRTEPAHVSKPNVEPLVQKLRELGWVARLTPRA
>NZ_CP042425.1|WP_149113582.1|7071585_7072113_+|hypothetical-protein
MPTDYATPHPQDRLAEATDAARRAEERNTQDVKKLSDALDAASKRPTDPNHRPFPRLKVTSAKDVEAVAAFAELLVACDRAGSVLDERQAGKHVRDWFLAVRKGDEDGALAAVASAKRELAGHLHGAEVSRIYDIVSDYVHELRNPADARVKAIISKLADLGFDVTPHKADATLA
>NZ_CP042425.1|WP_149113581.1|7068979_7071502_+|hypothetical-protein
MPNSLTDTILKIIVDATGVKSGVDAAVRDLDRLESAVERANRSAASVATRSAPASSSSSPSVTARSVRDIVRPSVPPRVFAPPSVERFVQQERRSIADVLRAESDRRVRQVETLRRQSNLARTLADDRQSFRSASAFTTFNPSSLGPGVGNSVATAGRFAGGLATTGGTFAAGGIGLLAGPLAGAVAGVAAVGFGKVIETIGDVGGRVIGTSLSVLTSAATEAIKQGSFREDAGVNFAALTGSQFRGDKVIADAEKYALDSPFRTRELLDQSKLLLSYGVSADDLAKRLRQLGDVAAGTGVDFRRLSLAFGQVVSKGRLQGGEVRQLTEAGVGIRDLASAYNELNGKNVSAAGFLGLVEAGQVSARVVERSFERMTQAGGRFFGLTEARAKTLSGRFENLGESVELSFQKIGLSFIKNTSITTFIDDIAKKVRGIDLSGADGLFKNLDATVGPFVTRVARGIGGVFGDVVPKQLDFDALDRGLKAFTRDTIPQILDAGRDVAVLFLDVASAMAKFIDLIDPLLPKQAALELLLRQVPGRNDFLLGGPLAAGQGQPPASRPIAQFAAAAEARANILRQANPGDRFRNAARGPFDFLDEIVGPQVNRGFQAVLGAVGGAFQGPDINRAALEAKRVNGLNRQAFADGNIPARLPPVFAADILKLPKALDELNGAVKSRIGPFKDAFESISDKILPDFGKRIEDFTARLGKPADQPFTDFQRNIQAANVLDGPFGRALGFEGKDLARIRGELGQELIGKFKSPELQPAPLVRAGSQEAEQALTRAVYESRNNEKSAQDRLAEAIEAARRAEEDNTKEIRALSDALKAGPPTPLFPVNDGVAFPL
>NZ_CP042425.1|WP_149113580.1|7068044_7068845_+|sigma-70-family-RNA-polymerase-sigma-factor
MTRNCDPAREFATDLHAVLQALTDPARPVLSPGDVRQMFSPRRPTGLRTRRRLTPRPVTPDPVAMVEENVGVIWVIINRHFAALMRIVGEDEVFQQAYLGALEAAERFDASLGYKFTTFMGSCVWGKLQDLLKSHRRAHGRPACDTAATTTPGVFDPNILRKTLVDPRPPASQGIEDSERAAFVVDRLLALAASDRDRTILAEWCDGDGTPRRFCDVAESLGLPTSTVRKVIGRIRSQILEAGLNGELGPDIAEWCGSNGDSAEEN
>NZ_CP042425.1|WP_149113579.1|7067620_7067968_+|hypothetical-protein
MCNALALTVGSLPASKTHKSGRRWAFLPSSDLASPSLGTLTIVQSKRDTVSYSVAVEDHQVLFAKADGSEVYGVNLKAGRPVRCSCTGFHFAKKCKHLDAAVEMIADGVLDVCHA
>NZ_CP042425.1|WP_149113578.1|7067163_7067472_-|helix-turn-helix-domain-containing-protein
MATSFGDELKRLRNERGISQQDMADQVAKLGVTFSRSFLGMLEQGNAERLGADVLFRICEVLGVKCTHFQVFLAPPVSAQSEESATVTPTPKRKPGRPKKSV
>NZ_CP042425.1|WP_149113585.1|7078151_7078367_-|hypothetical-protein
MAYHKLMDVDREVRTANRIARSRDIAQRELRYKFALKGLTPTDAELQAAADDAERRERQGDDEKRNDDDGE
>NZ_CP042425.1|WP_149113586.1|7078389_7078671_-|hypothetical-protein
MPLSLREKEEQAVLAAHYAKRDQRERDRIDRLKRITIAKLRGRLAIAGKKPPTRAEEKAAAEAAVRADEQDRAAARSREADDRNGVPAHRRIR
>NZ_CP042425.1|WP_149113587.1|7078768_7079110_-|hypothetical-protein
MAGEDKQPDRPDRMRRLFTGYSRGWITDGELARAGMDTLAECRAFSAVRWFLGSLSPAAVLAAEDYARLLTDPSRPSHVETGHHLADVTLRAQGLARRSFAEAILAALHVIRS
>NZ_CP042425.1|WP_168219299.1|7079221_7079722_-|DUF4142-domain-containing-protein
MQMRHAIVGIGLLLLAGTAVAADKPFDDAAFIKKAVSGGMLEVRLGELAEKMGQSDGVKKFGAKMVTDHTTANLKLLEIAKAAKVTVPDKLMDEHQKTADHFKAMKAGAEFDKHYVDDMVKDHEEDIAEFEKASKEATNPDLKAFAAKTLPTLKEHHEMVKKLQHK
>NZ_CP042425.1|WP_149113589.1|7079868_7080255_-|response-regulator
MNRPLRVLCVDDNQDAAVSTADLLNLDGFDARACHCGVTALAVAAEFRPDVCLLDLSMPGMNGVELGRRLREELTGLMRVIAVTAMGDAGSRMATRKAGFDAHLVKPVDPERLLAVLKGEDVTGPASF
>NZ_CP042425.1|WP_149113590.1|7080348_7080528_-|hypothetical-protein
MNRTTDAVPQTDGERESRVESAHQQARTRLALMRQAATNGREERRPAERTDPLRDLWRQ
>NZ_CP042425.1|WP_149113591.1|7080704_7080950_-|hypothetical-protein
MAITDELARRFVCAKCRASGGVVKTVPTISGWSVLFGGPSSSLLAVSCKGCGYTELFDADTLNRNRKGGAIFDSIYGEQRP
>NZ_CP042425.1|WP_149113592.1|7081547_7082852_+|tyrosine-type-recombinase/integrase
MARPRKSIPSYLPHTSGQARAVWTDRTGTRHFRMLPGPFNSPKSRTAFGTLLLEIEAGAKITAAPSPTGLSLAELMLAFLEHAERHYRKPDGRSTSELAECKLMARALREQYTNLPAAEFGPLKLKAVRQGWVNRGLSRSECNRRANLVRRMFKWAAGEELVDESVHRGLTAVVGLQRGRTSARETEPVRPVEDAVVDATLLFLTRHVRGMVEFQRLTGCRPGEACALRLSDVDSSHEVWQYRPTAHKTTHRGKSRTIAIGPRAQKLLREFPTPNPTAYVFSPSQAVEELLAARAAACRTPLLQSREARHIRKQGMKPRRRPSQRYCTHAYDHAVARACDRAFPPPGDLAQRSGETRAAWWGRLTDGQQEEVKTWRRAHRWHPNQLRHSFATLVRRRYGLEAAQVLLGHVRADVTQVYAERNEALAAQVVAEVG
>NZ_CP042425.1|WP_149113593.1|7083124_7083472_+|DUF1016-family-protein
MGRRRHCARVFYCLPAPRRHRHPDDRSTIGNILCRAKNRVVAEYALRDIDRPPAVFTSTSLAWLSPCPTNWRRNSARRPTIRPPAAPEGVPPAGLNGTGQPDRPTIRRQLGACGE
>NZ_CP042425.1|WP_149113594.1|7083954_7084791_+|hypothetical-protein
MTHLVVAVDNLIKEARGYYAKEQWDLTLVAVPTRLRPKGEGIGLQRCAPGSPNVWQVQNGALLCAAQSIRFLGSTEVPNVGPVEYIAFDGNGQAISTFVEFCGKAAAALFEARPRWFDRQRSGGPLTIWSTAIMFGSPSAYSLSACQPTGPWVLDRPWAGSLNALNDIFGLPALTFFEPDVLELPPAAEKRITPAWNRAARLLTLQNGQCKQYRRPAPNQFKILNTFDEDEWPKAIEDPLKPGKLAATIDSLNRNLQLIKFHLNTDGAGVYWTIQGFK

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Crispr_ID: NZ_CP042425_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_14

7567577-7567675

Orphan

Consensus_repeat	Method
GGCAACGGATCGTGCCGAGTGCGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_14

>merge|NZ_CP042425|14|7567577-7567675|CRISPRCasFinder
GGCAACGGATCGTGCCGAGTGCGACGAGGCCCGTGGCCGCCGGTGCAACCGCGACCGGTCGTGTGACGATAAGGGGCGACGGATCGTGCCGAGTGCGAC

>NZ_CP042425|14|13|7567577-7567675|CRISPRCasFinder
GGCAACGGATCGTGCCGAGTGCGAC	GAGGCCCGTGGCCGCCGGTGCAACCGCGACCGGTCGTGTGACGATAAGG
GGCGACGGATCGTGCCGAGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149113986.1\|7578453_7580736_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153237
NZ_CP042425.1\|WP_149113990.1\|7584708_7585863_-\|DUF21-domain-containing-protein	unknown	unknown	gnl\|CDD\|224173
NZ_CP042425.1\|WP_149113991.1\|7586128_7586497_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113982.1\|7566060_7566405_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|132044
NZ_CP042425.1\|WP_149113976.1\|7553989_7555396_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP042425.1\|WP_149113984.1\|7567119_7567356_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113987.1\|7580851_7581802_-\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|223730
NZ_CP042425.1\|WP_149113979.1\|7560500_7562054_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP042425.1\|WP_149113978.1\|7558962_7560456_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP042425.1\|WP_149113980.1\|7562598_7564035_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|235136
NZ_CP042425.1\|WP_168219353.1\|7589292_7589577_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NZ_CP042425.1\|WP_149113975.1\|7552342_7553317_-\|NADPH:quinone-reductase	unknown	unknown	gnl\|CDD\|176189
NZ_CP042425.1\|WP_149113989.1\|7582416_7584654_-\|sulfate-transporter	unknown	unknown	gnl\|CDD\|223732
NZ_CP042425.1\|WP_168219352.1\|7565814_7565985_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP042425.1\|WP_149113977.1\|7555522_7558876_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP042425.1\|WP_149113994.1\|7589003_7589213_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113985.1\|7568029_7578211_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271325
NZ_CP042425.1\|WP_149113983.1\|7566554_7566872_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|366166
NZ_CP042425.1\|WP_149113992.1\|7586884_7588288_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113988.1\|7581942_7582185_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149113986.1\|7578453_7580736_-\|hypothetical-protein	gnl\|CDD\|153237	cd03143, A4_beta-galactosidase_middle_domain, A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. This group includes proteins similar to beta-galactosidase from Thermus thermophilus. Beta-Galactosidase hydrolyzes the beta-1,4-D-galactosidic linkage of lactose, as well as those of related chromogens, o-nitrophenyl-beta-D-galactopyranoside (ONP-Gal) and 5-bromo-4-chloro-3-indolyl-beta-D-galactoside (X-gal). This A4 beta-galactosidase middle domain lacks the catalytic triad of typical GATase1 domains. The reactive Cys residue found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow in typical GATase1 domains is not conserved in this group.	5.1595e-11
NZ_CP042425.1\|WP_149113990.1\|7584708_7585863_-\|DUF21-domain-containing-protein	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.41074e-105
NZ_CP042425.1\|WP_149113982.1\|7566060_7566405_-\|hypothetical-protein	gnl\|CDD\|132044	TIGR02999, Sig-70_X6, RNA polymerase sigma factor, TIGR02999 family. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found in a variety of species including Rhodopirellula baltica which encodes a paralogous group of five.	3.88307e-07
NZ_CP042425.1\|WP_149113976.1\|7553989_7555396_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.3159e-41
NZ_CP042425.1\|WP_149113985.1\|7568029_7578211_-\|hypothetical-protein	gnl\|CDD\|271325	cd14955, NHL_like_4, Uncharacterized NHL-repeat domain in bacterial and archaeal proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	1.76657e-16
NZ_CP042425.1\|WP_149113987.1\|7580851_7581802_-\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	5.19132e-16
NZ_CP042425.1\|WP_149113979.1\|7560500_7562054_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	3.85456e-27
NZ_CP042425.1\|WP_149113978.1\|7558962_7560456_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	2.63124e-27
NZ_CP042425.1\|WP_149113980.1\|7562598_7564035_-\|ABC-transporter-permease	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	1.35488e-33
NZ_CP042425.1\|WP_168219353.1\|7589292_7589577_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.47313e-24
NZ_CP042425.1\|WP_149113975.1\|7552342_7553317_-\|NADPH:quinone-reductase	gnl\|CDD\|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP042425.1\|WP_149113989.1\|7582416_7584654_-\|sulfate-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	4.85339e-79
NZ_CP042425.1\|WP_168219352.1\|7565814_7565985_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.9341e-08
NZ_CP042425.1\|WP_149113977.1\|7555522_7558876_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP042425.1\|WP_149113983.1\|7566554_7566872_-\|alpha/beta-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.75478e-05

>NZ_CP042425.1|WP_149113984.1|7567119_7567356_-|hypothetical-protein
MKITCISDLLPVARERMPDVAEPFVEELAAFLWDEGYDRGCRGGDDWSRFLDSLPADMRNYRHRTRRPKSAILVRRHG
>NZ_CP042425.1|WP_149113983.1|7566554_7566872_-|alpha/beta-hydrolase
MHVLLAGDPTAPPLICLHGSLASSAHLLSELHLLADHFRVTLPDLPGQPALGPPVRVPYTGDSLPWWVLDVAESTGVDRLSLLGELGRVFRPEGSRADPDRRAPG
>NZ_CP042425.1|WP_149113982.1|7566060_7566405_-|hypothetical-protein
MSNESTQHLQSIVNRVRRGDPAARRDLLDAACGRLRRLTAHILSASFPALAGRHEVDSVVHETWLRLAKAMESVEPESVEHFFRLAAQKVRHVLLDLVERGRRGHSHDALGLDG
>NZ_CP042425.1|WP_168219352.1|7565814_7565985_-|sigma-70-family-RNA-polymerase-sigma-factor
MAELPDDERSVFEMHYYLDLPQAEIAAALALHPRKVSRLWLAATDKLSDCLAGSGN
>NZ_CP042425.1|WP_149113980.1|7562598_7564035_-|ABC-transporter-permease
MKRIATILFALAAVGGGAAWYWPSHRTPAVMRLPGTVEVQEVRLGSQVDGRVAAVKVREGDIVEAGTPVVWFDAEELAARRDQAQHRLEAARAAWEKARQGPLPEEIAEAKAATEPAQARLARVKAGNREEQKQQARADLDAEKAALRKAEDEFFRFNKLGVHSDLERETALAGRDTARGRVAGATAALELILRGSRAEDVTEAAAERARFEARYNLIRRGVRDEDKATAYAAVAEAEAALRFAEHQLREAVVAVPERCVVEVVSVRTGDLVAAGQQVVRVLRADDLWVKVFVPSTELGKLWVGQKVEVAVDSHPGRRFPGDVSQIATVSESNALVREKENGTLEQLSTTPVRTGELMVGKVVPYLCLSFVQFLTIATLMRVVFGVPVAGNFLTLPVINVPFVLAALGIGLMISAKANTREEAGQKVMGSVLPCVFLSGYIFPTESMPAVLQPISNLLPTTWMIDAARGVILRGAGWP
>NZ_CP042425.1|WP_149113979.1|7560500_7562054_-|TolC-family-protein
MVRTSFPRWCVRWFGVGCVGLLVAGHAFGQQPPRVNAQQSIPDAPPGTILQPGECPIDLGSALSLAGVENPQLLLARQRVLEATAVRQLAAAQLLPNVNVGTNYDLHRGVLQQSAGTILPVNRDAAYVGLGANSVGGGTVSVPGLNYNLNVGSAWYGYLATRQRQVTAGAAADAVRNDVLLRVCLAYLDLVRAEQRRAIAIQNRTDAAEIARLTDVYAKGGQGKKSDADRAAVELRRRDAETAQTEADMLTASARLCGLLNLDPTTRLKAVEGWAVPTPLVPATMTLPDLLATALLQRPELAARRSDIRQSLYELSLAKVLPFSPNVVLGFSAGGFGGGSNLIAAAGTGPRFGDFDTRTDLDVAVFWTFRNLGVGNLALARAADSRMKQSRLRELETLNVVRGEVAEAHARSAARLVQIDAAEKAVRASAEAYREDLTRIRGGQGLPLEVVDSLRLLNRSQTEYLDAIVDYNRAQFQLWVALGRPPADCLTRPVEAHVGPRVVALPSAVHQLSAAKP
>NZ_CP042425.1|WP_149113978.1|7558962_7560456_-|TolC-family-protein
MRILLLGVTVLFAAGCQTTPTAEPLSAFQARYVRKPAATTAVVQAKYETPASTPPVLAADGVPLRESPIDLGTALRLAGVENPTINLAREQIRQALADQLAADALRLPHLNAGVNVRVHRGTLQGGTGVIRNLNSQSVYVGGGVGALASGTVSVPGVQLFVHLGDAVYEPLAAAQRVFGSQSTAHAVQNAVLRDVATTYLELVAAEARLDVLTRATADVGDVARLTAVYAQKGQGRAGDANRAAANAELLRRRVGQAEEDVGVASARLCRLLNLDPTVRLHTPADTLAVPVRFVSEESLLDELLKRAIEARPEVYARTADIAAARTRVKQEKTRPWLPTVAVGFSGGGFGGGSNQVSPEFGPLQARTDFDVAAIWSVENFGLGTRARVRQANAVLGATVATFNTAVNDIRQEVAAALADAQAAARQIDTAKGAVATAEEGFSLDRERITQGQGRPLEVLDSFNLLLDARQELIRAVAAFDAAQFRLLAAVGETPRQN
>NZ_CP042425.1|WP_149113977.1|7555522_7558876_+|efflux-RND-transporter-permease-subunit
MTGLIRFSLGNPRAITVLMFTIAFGGLASVAVIPADILPVYKSPAVQVLTFYGGMSATNVEADITSRMERWTGQAAGTQRQESRSIVGASIIRNYYSDDTDPSSALTQVNSLATASIPTLPPGTLPPVILPYDPTSATPVGLVALNSTTQGESILFDTARYQVRNMIMASPGANAPVVYGGKARTVLAYLDRGRLQARNLSPTDVMDALDRSNIFLPAGDAKLGGTDYALDSNSMYELVDRMGDIPVRSDAKGVVFLKDVATPKDASLVQTSVVRVDTRRQVYIPVYRQQGSSTLGVVENLKANLPDMKARLTTPDVDLKLVFDQSVYVKNAIASLAEEGILGAILCSLVILVFLGEWRMTVIAVITVPVAVLGAIAALFGLGQSINVMTLAGLALAIGPLVDSAIVALENTHRHLGLGATPRQAAYLGASEVAGPAFAATLCTLLVLAPLVLIPGLGAFLFKPMFLALTFAVLIAYAMSLSFVPTRCAAWMKAHTSAHPVESHDVNYEHRNPHEHDEPTGLFGRAFAKWEAVLDAGIRGYTRLLGGVLQARGFVIGGAFAALAATLVILGPQLRREFFPEVDAGSFEIYARCPSGTRIEVTEGYVEAVEKYVKAKTGRDLELVISELGLTADWSAAFTPNSGPMDAVVKVQLKAERHASAQEYVDVLRHGFRDDPEFGELLKKVFEEKQAAGQLPAGVPPFTRDTLEFAFDAGGMIRSAMNEGRSTPLNVRILGKNQSKCRAVGEKILAEVKGVDGVVDARIIQRLDYPLYTIDVDRTKAASLGLNQMEVMKNVIAAFNSSIQFNKKNFWIDPVSHNQYYVGVQYPEGDISTLETLMDVPITSPTQKKSIPLRTIATLRRKNVPSEIVHNNLQSTIDLTMGVYGRDLGHVAEDVEAIVAKYGQERPGGGWVPFDPTDADHKPMEGAKINLSGEYQKMQTTFRYQAMGMAAAVVLIYFLLVALFKSYVTPVVVLSAVPIGLIGVVLVLFVTGTALNIQSLLGVIFMVGIVVSNTVLLTDFATNLQKTEKLLPTEAIRRAAAIRVRPVVMTALATFFALIPMSLGLERGSEANAPLGRAVLGGLVAGLLTTLFVVPCVYSLVVPKKFDDAANEEPLPG
>NZ_CP042425.1|WP_149113976.1|7553989_7555396_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MHPRNPATSRFRWLVLTAFLLGVAAGGWYVFGRSQPAIGRDANPGGNGDTAVRVEVAAPKLGGIDRICVQPGTIEPFESADLYAKVSGFLLERRVDIGSHVKEGDVLAKISVPEYEKQVEKDTAEVRRAEAKVVQMKAAVQSAEADLRSATALVALSQAEQKSKTSYRSYRQKQRERIKGLFAQQAIDAKLVDEQEDQYEAAFSAELAAGEAVNAAKQKEAAARSKVDQAKADEKYADAEVAVAKAMLDKSTVLLGYTLIKSPYTGVVTHRNFNRGDFIRSADAGGERVPLLSVERTETMRVIVQVPDRDVPYVNVGDPAVIEIDALPGTVLQTTSAHNVEVSRTSDSEDPHTRTMRTEIDVLNPEGKLRRGMYGNVTLMLNVGATNAVRVPSGAIVKRGDAGKGAVRVVRDGHIATVPVTVGTDNGVEAEVLKGLTTADKVVVRTTTTVEDGAAVTTSEAKPQAAGH
>NZ_CP042425.1|WP_149113975.1|7552342_7553317_-|NADPH:quinone-reductase
MTKAIRLHATGGPEVLRWEDVTVGEPGEGQARVRHTAVGVNFIDTYQRSGMYPIPVPGGLGSEAAGVVEAVGPNVTAVKPGDRVAYAGGPPGSYSEVRLIPAHILVPIPDGVADETAAAVMLKGMTAQYLIRRTYAVKAGEAVLFHAAAGGVGLIACQWLKALGATVIGTVGSDEKAGIAKAHGCEHVIVSTREDVAKRVKEITGGAGVPVVYDSVGKDTFLSSLDCLKPLGLMVSFGNSSGKVTPFDIGILSQKGSLYLTRPTLATYTTTRADLEATAKDVFDVIREGKVKVEIRHRYALAGAEQVHRDLEGRRTVGSIVMTP
>NZ_CP042425.1|WP_149113985.1|7568029_7578211_-|hypothetical-protein
MRPTFSVWLARLWNPARRPIRPQLPVRPILGLVSLEDRSLPATLGMATLFEGPTAGSDGTLVQASGAWTASTTEPWITVTTATGTGDGLAKFSFTANAGATRTGTVTVAGQTLTVTQAGTGYVAAGESRAIVDRVFSGPKSVAADGAGNVYVTDSGLKKYTATTGVTAPVAATIQYPYAVTVDGAGNVYAVDSNADKVKKYNPTTDVVTDLFTVPAVQTPIAADAAGNVYYYDSAATAIKKYSTAGVTSTVVSDLTGNVGALQVDAAGNVYYTMVVDSGYDLNSPFKYDAATQTSTALLPIDKAPWVLPDNLMVDAGGNVYVVQDDYTAYDLLKIAPGGQVSTVVSQFGQYLDTYLSGGAIYTLDSPAQSVVRYNLADGTTRTLVAGGYDRFGNLNGLVADATGKLYYNANYGFKRYDPTGAATQITFDGTGQYASLDAAGNVYFVTYDSATDANKVQKFDPLLDQIETVYTSPAGFYIDALDVDAAGNLYYAENGSVGGVATGALRKYDATAKTATDLVSIFTLSDIAVDALGNVYYVDETTDKVREYVKATGTSVDLITGVTSSGGVEVDGSGNVFVTTSGTIKMYSPATGAVTTRASGLTSPTFLTADGAGNLYVAESSPSRISILPRAFVDTSAVNTSTAAGTVTLTDRVVGGPGLTGVLSPLSNSPWLTVDSVTSSKVNLSYTEHTGAADRTGTVTIFGKSISVTQVVPPQPTVSAATVTNVTGQGATLGGTVTATGTSSITERGVLYAPTATNANPMLNGTGVVKVADAATTVGTFTAAVAGLSSGVGYSFVAYATNANGTTYTAVSAFTTLVTVQFAAATQTVAETSPGTFTVTVNLSGAASKDVVVPFTVGGTAVSGNEYSGAAAGSVTILAGKTSATITGTIVNNGYSPADKTIVFTLGANPTNAALGATTGHTITITSAVKPSVQFAAASQTVSETVAGTFNVMLSLSAASSVDTTVPFTVGGTATPDTEYSNVSASPIVIPAGQTSVNVTGKVLNNGYSADDKTIVFTTSSPTGADLGTNTMHTLTITSAPMPTVQFLSDSQSATAVSGTFAVTVSLSAISSLPTTVNFTYGATGDTAVEGVDYSDVSASPVVIPAGQTSVTITGKLAASPSATANPTLTFTLGTVTNGTAGGTAATTLTIVEPSLVPTQVDVGGLQFREANGLQPSGSTFMSSGTVQVGFKPAAGQPFVALLTLDGTTTIDTAALTITNTGAVKAIRPSNPVTLLTGGFTAASIAALAGAGQTGLTGATFTVASLTFTPSAISLDQANADVLVQGSLALPYGLAVSVSGTNHVVVSDTGIALSGVTASIPSTGFSLGSVEFTGLSLSAAYDSTANTVTLTGTATATLENKAGNVTLALGVGQGSTPGLVFTAGALTAFDASVTTDFTVRGVTISATDLTFAYSTADAKFSLSGTAGVAIDGLGDLSVTLGHGTDPGLVVTNGDLVSLDATVNSTFTVGELTFTAGDLNFAYTAAGDMFALTGTVTSKVTGLGDLGLTFGHGTAPGLVVANGKLTSLDLTLDSNLTVGGVAFAAKGLEFTYAAATDQFALAGTVGLTVGGIGNLSVTFGNASGPGLVVADGSLTSLNLAVTGDVTIGGVTFATKGLALGYTAATSQYTLAGTAAVTVGGIGNLSVTFGHGTDPGLVITKGSLESLHTTVNSSVTIAGVTFATKGLAFDYTAASGAYALTGSAGVTITGIGNASVTFGYGTNPGLVVTKGDLTSLDMTLDTDVAIGGVTFGTKGLRFQYAGATKAFALSGSADLTVSRLGTLNVTFGYGTNPGLVVTDGALTSLDMTLNTNVRVSSVTFSTKSLRFQYAADSNRFALSGSAAAAVTGIGNLSVTFGQGPLPGLVISNGSLDSLNMTVDSNITVGSVGFATKGLNFTYDSRQATFSLAGTAAVTVGGIGNLSVTFGKGGNPGLVITDGSLTSLDTTVNSDISVSTVQFSTTGLRFTYAAANSQYTLAGSAAVTVGGIGSLSVTFGYQGSAGLVITNGSLDKLDMTVDTNISVKAVTFTTKGLRFTYAATNSQYTLTGTAGVAVTGIGSLSVTFGNGTNPGLVITNGSLDKLDMTVDSNITVKSVTFTTKGLRFTYTAANSQYTLTGTAGVAITGIGNLSVTFGYNGNPGLVITNGSLDSLDLTVNSKIRVNSVTFSTEGLRFTYTAATSQYTLSGSAGVAIVGVGDLTVTFGYNGAPGLVITNGSLDSLDMTIDSKIRVNSVIFSTKGLRFTYTAATSRYTLAGSAGVTVIGVGDLTVTFGYKGEPGLVITNGSLDKLDMTVDSNIRVNSVIFSTKALRFTYTPATSVFTLTGTAGVTVIGMGDVSVTFGYDGAPGLIITDGSLTKLDATINSQFRVNNVIISTDKLRFTYTTATSQFTLSGAAKVTVIGMGQVQVTFGDGGTPGLVITDGSLTSLDVRVDAKFTVNAIVFTADGLRFQYTAADSTFKLTGSAGVGLIGVGGLKITFGTPADPGLVITNGELKSLNMTVGADFSVGLVTLKGKGVNFRYTAATSTFTMSGGLTATITGIGDITLTFGRGTTPGLQIVDGTLTAMALTVTSDVTFAGLTFGKADFGFKYTRSSGKFVIDGTASATYGFETFAVQLGNGTTGGIVVDTTKGTVDSVNGTLSNTLGVAGLTVGNVSLALNYANSVYTLSGTGSVTIKSSLDLPSFFKTFIDLKGVSLTLGSVNLTSSYTAGKNSESYTALSVRLAGLDVGIKVYFNGSVDITGVSNAIVQGLLNAAGKVVDAAGKVVNKAASVVKSVGSAIYNASPCILDNQIAGAMVFYDANGNGVLDAGEPNTVSAADGTYRLALPEGASGLIVAFGGTNVATNLPNTMTLTAPAPATMVSPLSTLVQAVRATSPALSIDEAAATVAAALGIPDTINVLRENVIDLAMTGRADAGRSLTAAVELAGLSNGIAALVGRSGADVDAAFFNSLAAAIGNGNGDPGLANDAAVRDLILDTAGRLNVTLDDALVTGAAAVLAGINRHFEATPVGAGADYMRHIVAAQIVAGTDVNTALAAAATGQRDIASVVAEYTGAAFAAAAAATPVSTLAATVSNTAPWYALAAGDGGGARVQVFDQATGAKKADFFAFESSFRGGATVAVGDVNGDGTPDVVVAAGIGGGPRILVIDGTKLDQISDAGEISPTALLADFFAFESSFRGGASVALARLSGGLGLDIVVGAGVGGGPRVRSFSFAPQAAGGVAQMTGLIGDFFAFSPDARVGVNVAAGDLDGTGRDNVIVGAGAGGGPVVAVYNPDGTLRNQFLAYDAALRGGVSVAAGYLDGSAKAQLVTAAGPGGPGVVNVYADADDIPDRTIDAFEPSFTGGVSIGTVTTAAGTNLVVGAGPGGAPRVRVLSDDGQTIDDYFAYDASFLGGVTVG
>NZ_CP042425.1|WP_149113986.1|7578453_7580736_-|hypothetical-protein
MPSRLAATLALLFLPALAAAQAKPPFGEPLPPQPFEQSPFRPVAVPEWVRGTTGVGYTLSGLDTAGRTAAVKHGVTISEMGFVDPFYPYYDSALLKKRSPHVGLDRLPRDIAEYQKLGLRILGVYPPTLQGEVYEAHPDWRRIPTDTTTIPQVDMKKFGHGGMLCPLGPYGDFFIDVLAEILEKHPAVDAFSFDGLHHGGVCYCEHCRKNYKADTGKPIPPKPDLNDPAFRRYQHWADRRLEALVAKAQARLKAIKPDVALVTWTTNAGRYGHFLSLPRNMSARMNLLFDAPDQEFWADESNRGNTVVPAFANAYAWAVTNHRVAFSEPYLMSHGNPYGKDSFPPHEIERRMMLSLTHGAGPSIAVAQPKRLRAAVDHGLDEVLRRKPWLTHKSPEPWAALLMSDNTRTFYGREAGRVEERYLAGVFGTFRATLEEHLPTTVINDWNLTADELKKYAVLILPNAASLDDKQVKVIDEYVRGGGGVVASVDTSLFDEYGDPRAKFALGELLGVEYLGLPTAAGGKADLDVNFAKGIGPDYWEKRKNVFDLTLGVSWLNAGKLSEYVGTEPVTFKGPAVRVKPAAGTQILGTLRVKGDPKAEPFPAVVSRTHGQGRVVYLPAGIDAGYYLYAYPYQRCLVANAIRWAANGVKPPVTVTAPMCVQSTVMRQTKDGTRRLIVHLFNDVNTTGGKAYPVDDVPLREEVLPVHDIRVTFRPGFKLGPIRLQPDNTELKATETPDGVSVVVPRLDVHAMVVVELADN
>NZ_CP042425.1|WP_149113987.1|7580851_7581802_-|alpha/beta-hydrolase-fold-domain-containing-protein
MSVAWTRSLGVGMLCVLGFCPGQPARGADEKDVLSLPDPKPLVPGAKVVTLWPKGSPALRAMPGSDKPEQFNMAKGRTDRINSVENIHNPSIEVHLAPADKANGTAVIVAAGGGNKTCNVGAEGTDIADWLNGLGVHAFIERYRLKPYDSTKDAVADTQRSIRTVRANAKAWGVDPKRVGIMGFSAGGEQAAWVTLRFDDGNAKADDPIERESCRPDFSVLVYAGWARMDLTKVPKNAPPTFLTSAGVDDAFHARQTVEFYDALFKANVAAELHIYAHGGHGGAISPRKGIPFGTWQLRFVDWAKDLNLLKEKGAK
>NZ_CP042425.1|WP_149113988.1|7581942_7582185_+|hypothetical-protein
MVAYFVSKGIDPTREPGLAVVERSLIEEYGPAEVTAKAGPAGAVSPTFRTGPACPSELPELAPTSGSERTSQSKGRHLLA
>NZ_CP042425.1|WP_149113989.1|7582416_7584654_-|sulfate-transporter
MPFSNSTSPPSVTRDIAAGVVVFLVALPLCLGVAHASNAPLISGLLAGIIGGIVVGLIGRANATVSGPAAGLTAVVAAQITTLGSFPTFLLAVVLAGVLQIILGLLRAGFLAAFVPSSVVKGLLSAIGIILVLKQVPHVLGHDTDPEGEMAFVQPDHENTFTEYARLVGDIQPGAAVIGLASVALLVVWGRWKPLKQSPVPAPLAVVLLGVGAAAAFRAMGSPWAIERSHLVQVPIANGPGGFFDLLQLPDFTQWANPAVYLAAVTLAAVASLETLVNLEAVDKLDPLQRNSSPSRLLFAQGIGNVAAGLIGALPVTAVIIRSSVNLNAGGRTNISTIVHGILLFASVAFLPAWLNFIPLSSLAAILLVTGVKLASPVLVRQMWGEGRHQFIPFALTVAAIVLTDLLVGILLGLAVSTGFILWSNVRRPLRVIVERHLGREVVRVELANQVSFLNRAALARVFDSVPAGGHVLLDAQQTDYIDPDVLALIREFDERTGPARRVEVSLVGFRTEYRFEDRTQFVDYSTRDLQTAVTPAQVLQILKDGHERFRTGRRLTRDLGRQVAATAAGQHPLAVILSCIDSRAPAEIIFDLGVGDVFNVRVAGNVTSRKILGSVEYAAAVAGAKLIVVMGHTRCGAVGAAVDLARSGRTAAEATGCQHIDHILTDIQQSVASAPPTADPLPPAERAVLVDTVARRNVQHTVETMIRESDAIGRLVREGRVRVVGAMYDVATGGIEFLGGPSAE
>NZ_CP042425.1|WP_149113990.1|7584708_7585863_-|DUF21-domain-containing-protein
MDCFAVAAPPDVHWAWTVLSLLSVPALVALNGFFVAAEFALVGVRKTRVEEMVRQGVPRAGAVREAVGHLDRYIAATQLGITLASIALGWLGEPALSRVVEPVLAIGLPAEWAGPMAHTVAVAIAFGLITFLHVVFGELIPKTLALQSPDRTSLWVAAPLVVFARLARPAIAAMNGVGNAILRRTGHEPAGGEAMLHSVEELGLLIEQTEEAGVLSHQQAEFVRKVFTLSGKRVGDCLVPRERVAGLALGTRPDQVLEIVRRGAHTRMPVYAGDLDNVVGVVNTKDLFYLFSLKGIVVLEDALYPPLFLKPEDNVADALELFRRERRPLAVVRDAAGKTVGLITMEDVLEQIVGEMEDEHDRPTPKLRVRPRLPLRLYGSPPPM
>NZ_CP042425.1|WP_149113991.1|7586128_7586497_-|hypothetical-protein
MMPVAFSDLLVPRFGLRIFNQFRSFVIALQFVAYKLALVLVLATSGFSGGVVEDSAESTETLKELVCVSFTRPLPVTDTTAVRHPVIRTAAGVVTPGATTPSFPSRHLSHSLPNGLRAPLRC
>NZ_CP042425.1|WP_149113992.1|7586884_7588288_+|hypothetical-protein
MTRWFVLVLVAAVGWLTQAGAVWAAEPVGRYAVVVNKGVAAGPWGKVVKFLETKHKAKTFAYDKAPEDVRKDVGAYRPRYVCFVCPPTEDFPAFAAVANKFCRTLDDDPYVDAIWGILTGLDADHAMELATAEPVVIRRAFTKTLGPWLNWVPEGEYVTEWTRDRGELGAKKVGTDFAVKTGGPTSDADDAKLVHKLLAEDSFDLIIGSGHGGHNNWMLMYPSGKGFLTAKDGKLAMTASGVDLPLAGKRPKVYWAVGNCLTGVVNSGRNNFKDSYALAWMKNGTRQYVGAVQSTWYELNWNMADWFLKQEGRWTFSESLFLLRQWSHYLLTENVVTGRDREGTAFTDGIFVLYGDPALEARVEKTRDPALTETLDVRETGVKDVVRMTYTVTVNFVGEGNKRTAEKFGGWRIFCHLLPYQVTDVAIEKSDFAKVVCPGETLIWDAGKGLKVGDVRSVTFTAKRVPD
>NZ_CP042425.1|WP_149113994.1|7589003_7589213_+|hypothetical-protein
MAEGPRPESRRTPGRSSDARPAGGFVPVRVVSDAAAEVVRPGGVVLRVPVTADPAHVGRLVAAIRGATC
>NZ_CP042425.1|WP_168219353.1|7589292_7589577_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MAAALGRDPASGDLFVSKNRKGNRLKVLAWAGDGFALYLRRLERGTFAFPAAGGVGVVVTPAAQLAMILGGLDPAAARSRKRYARPDPANPRTV

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Crispr_ID: NZ_CP042425_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_15

8569816-8569907

Orphan

Consensus_repeat	Method
CACCGCAGACGTTTGCGGTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_15

>merge|NZ_CP042425|15|8569816-8569907|CRISPRCasFinder
CACCGCAGACGTTTGCGGTGGGGGCTGGTGAAAGGGTCTCGGTGATGGCGATACCATTCCCCGGTGGAACACCGCAGACGTCTGCGGTGGGG

>NZ_CP042425|15|14|8569816-8569907|CRISPRCasFinder
CACCGCAGACGTTTGCGGTGGGG	GCTGGTGAAAGGGTCTCGGTGATGGCGATACCATTCCCCGGTGGAA
CACCGCAGACGTCTGCGGTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149114720.1\|8572963_8573254_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP042425.1\|WP_149114711.1\|8563687_8564830_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|316042
NZ_CP042425.1\|WP_149114710.1\|8563070_8563388_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225848
NZ_CP042425.1\|WP_149114719.1\|8572454_8572787_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149115730.1\|8557771_8560267_+\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_CP042425.1\|WP_149114714.1\|8565885_8566452_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114721.1\|8573328_8573829_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114717.1\|8571205_8571976_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219425.1\|8573905_8574280_+\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP042425.1\|WP_149113301.1\|8570217_8571084_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114724.1\|8575111_8575639_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|288228
NZ_CP042425.1\|WP_168219426.1\|8574320_8574761_-\|BLUF-domain-containing-protein	unknown	unknown	gnl\|CDD\|377423
NZ_CP042425.1\|WP_149114718.1\|8572010_8572409_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366911
NZ_CP042425.1\|WP_149114712.1\|8564826_8565336_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113300.1\|8570017_8570221_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149113298.1\|8568977_8569388_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114709.1\|8560366_8561236_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP042425.1\|WP_149114715.1\|8568366_8568918_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367983
NZ_CP042425.1\|WP_149114708.1\|8557143_8557572_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379279
NZ_CP042425.1\|WP_149114713.1\|8565332_8565812_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149114720.1\|8572963_8573254_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.16943e-11
NZ_CP042425.1\|WP_149115730.1\|8557771_8560267_+\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_CP042425.1\|WP_149114711.1\|8563687_8564830_-\|AAA-family-ATPase	gnl\|CDD\|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	1.22515e-28
NZ_CP042425.1\|WP_149114710.1\|8563070_8563388_-\|hypothetical-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	1.35193e-05
NZ_CP042425.1\|WP_168219426.1\|8574320_8574761_-\|BLUF-domain-containing-protein	gnl\|CDD\|377423	pfam04940, BLUF, Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein. AppA is involved in the repression of photosynthesis genes in response to blue-light.	5.66601e-37
NZ_CP042425.1\|WP_149114718.1\|8572010_8572409_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|366911	pfam02082, Rrf2, Transcriptional regulator. This family is related to pfam001022 and other transcription regulation families (personal obs: Yeats C).	0.000152855
NZ_CP042425.1\|WP_149114724.1\|8575111_8575639_+\|hypothetical-protein	gnl\|CDD\|288228	pfam11336, DUF3138, Protein of unknown function (DUF3138). This family of proteins with unknown function appear to be restricted to Proteobacteria.	0.00187295
NZ_CP042425.1\|WP_149114709.1\|8560366_8561236_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.56834e-102
NZ_CP042425.1\|WP_168219425.1\|8573905_8574280_+\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	2.01352e-08
NZ_CP042425.1\|WP_149114708.1\|8557143_8557572_+\|ATP-binding-protein	gnl\|CDD\|379279	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain.	9.85829e-32
NZ_CP042425.1\|WP_149114715.1\|8568366_8568918_+\|hypothetical-protein	gnl\|CDD\|367983	pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.	0.000551563

>NZ_CP042425.1|WP_149113298.1|8568977_8569388_-|hypothetical-protein
MRPPPIELSAVSAAGATFAGVPVAAVRLVLANGNVLRLRLAATAHPGVVTAVTGAPAEGRPEPFCATECSRDLLGVLRASDGPLVLSAILARLESRNQLHGESTVKRALAAMVRAGVLANPGHRVGYSIAGVGQSE
>NZ_CP042425.1|WP_149114715.1|8568366_8568918_+|hypothetical-protein
MCRPKPAGADVPPVDLLALWPWVEKIALRVAARYLLWGEAALDDLISAGYVRALEKIPHFRPDDPKAAADPNGAFRGWAYRDVMTYVQREAARLRGGGTFRSPRREPGRDPVIAKPISDFEGGRQGERDEPFRAEDVAEEFRDQLVTEPLPRTPEGDDCWWEGMLEPHHHLQKPFDLSEFHDE
>NZ_CP042425.1|WP_149114714.1|8565885_8566452_-|hypothetical-protein
MIPVPPPPSSAAQVYWEEFYRIAAISELIAAVDPERAGPRPTAFAAVYQEQIEFRTLHEFLQACAIIASAEQALPGIVERVQALADRIAAEDAEAQDVADVAPERVVQLPSEPVAAATDDPPPLTPEIEEAFRKLAARRGDARKRYLALMLDFLDGGDRFLRLDEEAEREEAARRNHRPKNRLTKGGA
>NZ_CP042425.1|WP_149114713.1|8565332_8565812_-|hypothetical-protein
MNSPDPTSADRLSESIAAIARAAVAPLLNDLAERTGTLEIVVARDVLHETAVGPSESSGEWRARVSGPEPRAATPKVGKPEAVSGALTEADLWSVSALTLMDEANRGAKTGPTAAARGRREKQAARVLLDAVAVLGRAEAMSPGVVGRLAAAHAARGGA
>NZ_CP042425.1|WP_149114712.1|8564826_8565336_-|hypothetical-protein
MMVVQEPGPVTPATVPELRRWAAESRFPRKQLLTAVFDWAEADERVHRLDVAEAFRRRGQPPMADEYAAAVSARTAAFGRLEELRDYVGEIHLSGFAHALDRLPDELGDLLARAITLPGAKIALVRCLEVLLGPTFDYLVEQNATLRAETAELRGRVADLEAVAAGVDR
>NZ_CP042425.1|WP_149114711.1|8563687_8564830_-|AAA-family-ATPase
MTAINRIKQRVERDGHPATVKLAKGVEYAPDLVRMSDVQAVPVPWLWADRIPLGRITLLVGRPGAGKTWFTTWLAAMVSRGWSFPDKCHGTAGSVILMNAEDSAADTLKPRLEACHADCTKVHTLTSARATLADGTTASKVLTLADVDQIGQALAAVPDARLLVIDPVGSFIGGRVDAHRDNEVRGVLSPLAALAEQHKVAVVLVAHTKKGGGEIADDTALGSRAFVGVARAAWHLMRDPEDKDRRLLLPGKNNLAKERDGLAFRLEGDPTTVVFEDGPVTLSADDALANEARSHAEKRKPGPRADARMKAAQWLGEQLASGPKTPRELEEAAEKIGLGLRTLQRAAEDMGVERNKTYAGGWLWKLPTSGGTAATVHDTP
>NZ_CP042425.1|WP_149114710.1|8563070_8563388_-|hypothetical-protein
MPDRDPGGAATLDDVVGLLRELVAAARPAPALLDIGEFAALMAIGESTLERLKATPQIGPQPVRLGGSVRWNRAEVTAWLGRRNHRGELFDARTWPAVWKQIQSA
>NZ_CP042425.1|WP_149114709.1|8560366_8561236_-|fumarylacetoacetate-hydrolase-family-protein
MRLATIFSSHGPAAALVVGDQFIDIHATDPGLPGCVKNILAASPAVRQAVADTANNPKAVKYAANAVKLLPPVPKPSKIVCVGLNYRDHAIEGGKAIPTEPVLFAKYPNTLVAHGEPIVLPKVAEKVDYEAELVIVIGKTAKHVPNDASAFQYVGGYTCGHDVSARDWQFRGEEKQWTIGKTFDTFAPTGPWIVTADEKLDPHNLQIQLRLNGSTMQNSSTKEFIFGVPTMLAFITQVITLQPGDLIFTGTPPGVGISRKPPVLLKAGDICEVEIEGIGTLKNPVVAEA
>NZ_CP042425.1|WP_149115730.1|8557771_8560267_+|DNA-mismatch-repair-protein-MutS
MMQQYWDAKKAHPGAMVMFRNGDFYELFEDDAVVGSRVLGIRLTKRDEKIPMAGVPIEKLEHYLGILIRSGHRVAVCEQMEEPGPGKKIIRRAVSRVVTAGTITEDELLDPRRANHLAAVLRTKNGPVGLAWVDPSTGHFFACDVDSSRLADELARIVTAECLMMESDANAVTALFAAHPPKTTTPRPDWTFDPVTATNAIRQHFGVSTFTGFGFDDHQPCLIAAGAILHYLQETLRASLAHVRRIVRHRADSHLVLDEVTRRSLELTRTLRDNNREGSLLAVMDRTVTPMGARFLHDALLAPFNSVTAIDARLDAVEELLREHALRGDLRSLLETASDLQRLTTRASTGRATPRDLGSISRTLQLLPKFKAKLAARRSALLTELDGKLELCPDLRELLDASLCDELPQTAKEGGLIREGYHAELDQLRSLAKSGKDWILQYQATEVTRTAINSLKVGYNQIDGYYIEITNANETRVPENYKHQKTLKGAKRYYTSELREYEEKILSADDKAKALELELFTQIRNHIAAQTHRLLTTAETLATIDALQSLADVAAARNYVRPKVVADATLDIREGRHPVLDQTLPAGTFVPNDVRFGEADGLFWLITGPNMAGKSTFIRQVALITLLAQVGSFVPAAAATIGITDRIFTRVGASDELSRGQSTFMVEMTEAANILNNATSRSLVILDEIGRGTSTYDGVSLAWAITEHLHSVSGCRTLFATHYHELATLSNTLPNLRNYNVQVQELEQEVIFLHKIAPGNADKSYGIHVARLAGVPETILERAEEVLAALESKPAPTGKSKRYIKPPVEMIPPENPKRKARNAGPSLFGEG
>NZ_CP042425.1|WP_149114708.1|8557143_8557572_+|ATP-binding-protein
MPSTSVKVAETLPTELAEVRRVQSDIKDALQANGFGERDMFHIELAMEEALVNAMKHGNQLDTDKAVQLHYTVTPEQFDVRIEDEGGGFNPDDVPDPTVPENLERACGRGLYMIRCFMTEVRYIGKGNVVAMTKKKSPPDEE
>NZ_CP042425.1|WP_149113300.1|8570017_8570221_-|hypothetical-protein
MTADGPPDPVATLLLASLSARAVEFLAAVAATAAGGNRPGHGVRVEVSAHGVTVTVAVDPVGGLPSR
>NZ_CP042425.1|WP_149113301.1|8570217_8571084_-|hypothetical-protein
MKTTKTKTRTLVETNGFIPHGEQCCADPACGARTAVTAVKRTYCTGYGSDCPPVDHPDDTIPVAFADGRTGDVLSDRVDHFLAAVASESGDWGPYRGVGPLGAAAVVGVELRAAASDECRRMAEAQRAVRDVAAIVGEFAGEHRRFCSCSLCAFWSTGSGDRGRAARRALRLARELVKTSAAFLEAVREAAPDHRAFKYEHIIQYAPWTDPFNQGVPTAPDLVAAARERLAVSRAAVHTDPGQAGRYARALGIPYVGRFPADPGEADDDAMPDAIAERLAGGVIGEGL
>NZ_CP042425.1|WP_149114717.1|8571205_8571976_-|hypothetical-protein
MIRSLDFFHGYARVTFHDGSAVDVKCKCWGPCASDAEARHVAAVVALQARAAHSPEMALIARLDKLLNEASEVCFRLYETIRSGNSDLWDLWRLLMVDPPPGVPKTPRKIRLRPPTREQRRTDPVGQRRSIPHQVATLQGRLNHLWLNLQGELLERVTFLHVVSAAKLSHAPEYLSGQRVTARADTTLGDVTDYYPLGATLPPLPPVPTEPTKPTKPTRPKSRLRVIPPYRFNLPPARKGHRELLPPANGKLRPRE
>NZ_CP042425.1|WP_149114718.1|8572010_8572409_-|Rrf2-family-transcriptional-regulator
MTTSAPVDLAALWHAGATLGGLPVASVRVTLANGAVVRVRLAAADSACPVPVAAPPPTTFRPNPCSRDVLAILEAAEGPLVLPDIRQRLENREQLHGESTVRKVLAAMVRAGILTNPGHRAGYSLARPPSAT
>NZ_CP042425.1|WP_149114719.1|8572454_8572787_-|hypothetical-protein
MLCVLPVAGSLPASKTHKAGRRWAFLPSADATSPSLGTLTIVQSKRDTVSYSVAVEDGQVLFCKLTDGEVYGVTLDRSGRPVKCSCPGFCFQKTCKHCDTVKELKADGVL
>NZ_CP042425.1|WP_149114720.1|8572963_8573254_+|helix-turn-helix-domain-containing-protein
MTFPFAKMKQKREELGLTRKELAEKTGLTWRNIESLEQGLKLNPTLETLAALCKGLEVDCGFFFSEDIDLPAPVVGRPKKAATPQTPAPPAKVKRK
>NZ_CP042425.1|WP_149114721.1|8573328_8573829_+|hypothetical-protein
MHAIVDSNLVSLRAHERTRGANMTLGGYHMSEVIPTEEFVIRRGLLDQADGDHLYLISQFLPFTLGRTGLARDVLRDPAPGGIDLAKAAGITVAGIDLRTSPGYEPVIVTASVARGPLLVIDGHHRLTAHILAGRPLDGVVVYVCEHHRLMDWQRYGYVPPTMRLT
>NZ_CP042425.1|WP_168219425.1|8573905_8574280_+|TIGR02996-domain-containing-protein
MTDRAELLAAITAAPEDDLPRLVFADWMEECGEELIARFICRMIVADLEGKPQFDESTEVVADQAALAALWFNSFASAFGVEKFRVNRRFISRVELPVGTFVARAADLFRSQPIVEVDLTDAAR
>NZ_CP042425.1|WP_168219426.1|8574320_8574761_-|BLUF-domain-containing-protein
MLQVVYVSAAGLPFTQAQLVALLKKSRAKNASLGVTGLLLYHAGSFLQVLEGPDAAVDALARTIAADDRHHRVRFLVRRDAPEAAFAGWSMGFVDVTRDDYGDVLGHVDYLLGLNATPSFWDQDLLQMLLGRFRAGALRQHVGTVD
>NZ_CP042425.1|WP_149114724.1|8575111_8575639_+|hypothetical-protein
MRKRSTLALMLAACGCQAVKERAFSPVTARLDLANEQLATGVRHVEHGVAKLTEVDAKLTETNQRVARIEAQLKATDDRMARLEGQLARTDKRVEGLQGDVATATKAVGRVDATAITLGATVTGMATTLTATAKRVEVMDGRLADANKKVDETNKKLDVVVEAAKKVPGVAPPKE

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Crispr_ID: NZ_CP042425_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_16

8628253-8628341

Orphan

Consensus_repeat	Method
GAAAACCCGATCATGTCCGGGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_16

>merge|NZ_CP042425|16|8628253-8628341|CRISPRCasFinder
GAAAACCCGATCATGTCCGGGTTTCAGGTGAGGCGCCGGAAGCGAACAGCCGGGGGGCTCACGCGGGAGAACCCGATCATGTCCGGGTT

>NZ_CP042425|16|15|8628253-8628341|CRISPRCasFinder
GAAAACCCGATCATGTCCGGGTT	TCAGGTGAGGCGCCGGAAGCGAACAGCCGGGGGGCTCACGCGG
GAGAACCCGATCATGTCCGGGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149114780.1\|8636182_8636416_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114771.1\|8626954_8628196_+\|bifunctional-DNA-primase/polymerase	unknown	unknown	gnl\|CDD\|378140
NZ_CP042425.1\|WP_149114765.1\|8621865_8622072_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219432.1\|8628677_8629595_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237512
NZ_CP042425.1\|WP_149114766.1\|8622114_8622624_+\|DUF2924-domain-containing-protein	unknown	unknown	gnl\|CDD\|371394
NZ_CP042425.1\|WP_149114777.1\|8635202_8635556_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219434.1\|8629860_8630784_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP042425.1\|WP_149114776.1\|8634804_8635203_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_168219433.1\|8629591_8629861_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114774.1\|8630865_8632308_-\|heavy-metal-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|273593
NZ_CP042425.1\|WP_149114768.1\|8624200_8624623_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114762.1\|8618878_8619892_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|238121
NZ_CP042425.1\|WP_149114779.1\|8635796_8636186_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114763.1\|8620099_8620462_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114769.1\|8624799_8625126_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114778.1\|8635552_8635786_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114770.1\|8625470_8626958_+\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|319267
NZ_CP042425.1\|WP_149114767.1\|8622620_8624204_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NZ_CP042425.1\|WP_149114775.1\|8633525_8634734_+\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|319259
NZ_CP042425.1\|WP_149114764.1\|8620809_8621700_-\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149114774.1\|8630865_8632308_-\|heavy-metal-sensor-histidine-kinase	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	7.20246e-119
NZ_CP042425.1\|WP_168219434.1\|8629860_8630784_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.8301e-52
NZ_CP042425.1\|WP_149114762.1\|8618878_8619892_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	6.30088e-87
NZ_CP042425.1\|WP_149114771.1\|8626954_8628196_+\|bifunctional-DNA-primase/polymerase	gnl\|CDD\|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	7.157e-09
NZ_CP042425.1\|WP_149114766.1\|8622114_8622624_+\|DUF2924-domain-containing-protein	gnl\|CDD\|371394	pfam11149, DUF2924, Protein of unknown function (DUF2924). This bacterial family of proteins has no known function.	1.2707e-41
NZ_CP042425.1\|WP_168219432.1\|8628677_8629595_-\|hypothetical-protein	gnl\|CDD\|237512	PRK13800, PRK13800, fumarate reductase/succinate dehydrogenase flavoprotein subunit.	5.51906e-17
NZ_CP042425.1\|WP_149114770.1\|8625470_8626958_+\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|319267	cd16410, ParB_N_like, ParB N-terminal, parA-binding, -like domain of bacterial and plasmid parABS partitioning systems. This family represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	2.77939e-07
NZ_CP042425.1\|WP_149114767.1\|8622620_8624204_+\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	1.32583e-44
NZ_CP042425.1\|WP_149114775.1\|8633525_8634734_+\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|319259	cd16402, ParB_N_like_MT, ParB N-terminal-like domain, some attached to C-terminal S-adenosylmethionine-dependent methyltransferase domain. This family represents domains related to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, fused to a variety of C-terminal domains, including S-adenosylmethionine-dependent methyltransferase-like domains and DUF4417. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	5.76133e-43
NZ_CP042425.1\|WP_149114764.1\|8620809_8621700_-\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.12708e-17

>NZ_CP042425.1|WP_149114771.1|8626954_8628196_+|bifunctional-DNA-primase/polymerase
MTAALTTRDYLQAALWYRSWGWACLPVSHAVADKRPTVRWKALQRRKPTDRELGRLFAVRPDRVTGLAVLLGRASGGPPAGCLACRDFDAAAAYFRWASLRPRLAAALPTVRTRRGFHVYCYLPAEVFVDFGPGDGDLRCVATRYAVLPPSAHPSGVRYAWVRGDPARPDFPLLTVEATGFLADRADKARSPGRPRTALTPAAQPARKADKDKDLLCPPRGVSDAAGGSPGPDARWASLPAAEREAVLKTLPRRAGERHRRLFELARRLADVRPGVPAGHWAGVVRAWWRRAEPVVRTKDWAVTWADFRAAWGRVRTPASRSPPAVALAAARGADVPPRDRLRLACRSLAGLTGGTFYLSARGAAAATGLGKTRAAELLAGLVAAGELIVRVPGRRSASARLATRYALGPLGD
>NZ_CP042425.1|WP_149114770.1|8625470_8626958_+|ParB-N-terminal-domain-containing-protein
MTDEDDEVDANDECDEGEESDDDGGGPAAAIVHSLAVEWAALEGLTPAAVNDRLYRPVRDDDPGVVALAEAMGRDGGVLEPIVVTLDRVVLSGHRRRAAARLAGFDPVPVRVYPIWSADPAFVRLLRTFNQQRVKTFDEQIREAVIDADPHTTALEVEAYEAERDATYRRRVAAADIAPIAVTAARRRNDISAAKRPMLDAVIRVVQENREYWPLSNRQVHYRLLNDPPLKHARKPGSRYRNDLASYKDLCDVLTRARLAGVVPFDAISDTTRPSTQWRSWGHAQAFVREATAKLLSGYARDPLQSQPAYVEVLVEKLTAETPVERAAAPYLVPYCVGRGYPSLDARYQLAERFRASGKRRFVLLVLSDFDPEGENIAETLCASLRDEFDVPDITPFKVALTEDQVGRFGLVPSMEVKRSSSRAKGFVGKHGSQVYELEALPPARLQQLVTDAIESVLDLGAYRRERAEEARELQELVARRRVLLDAVGGLGGGA
>NZ_CP042425.1|WP_149114769.1|8624799_8625126_+|hypothetical-protein
MVASDKAGLSAPRRALVELVQERNFGRVEHLPVRGGEPVLDPPPRVVREVKLGGENDPRPERALANFRLKRQWVELFELFDAVGDGTVDVLEFKNGLPFKALVADPAR
>NZ_CP042425.1|WP_149114768.1|8624200_8624623_+|hypothetical-protein
MSENGVLTVVCDVHVDRRGRGARKEVRPGPDPRRTQPPGRVPRVARWMALAIRCDELLRDGVVDRYADLAELGQVSRPRVTQIMNLLGLAPDIQEELLHLPRTTAGRDPILLSDLQPIAATLDWGRQRKLWRALRCRHGG
>NZ_CP042425.1|WP_149114767.1|8622620_8624204_+|recombinase-family-protein
MTKRAKAAADTRPVVRCAIYTRKSSEEGLEQEFNSLDAQREAGEAYVRSQAGEGWTCLAERYDDGGFTGGNTDRPGLRRLLHDIAAGRVHCVVVYKVDRLSRSLLDFAEMMRTFEQHQVGFVSVTQQFNTASSMGRLVLNVLLSFAQFEREIVSERTRDKIAATRRKGKWAGGWPVLGYDVDPAGFKLRVNDAEADRVRAVYGLYLDRGSLLPVVEELASRGWANKRWELRKGGFKGGGPFTRTSLYGLLTNPVYVGKVRYKDEVHAGEHAAIVDPAVWQRVQAHLAGNGRGGGFSRGGPAALLKGVLRCTACDAAMSPTSTTKGAKSYRYYTCTAAAKKGWKTCPAKSVPAHQIEQVLLRQVRAIGTDARLRAEVLAQARQQDEARTAELAKEQKALEFDLKGWHGELRHLSGLLRPGDGNEPVIRRLAELQERIAAVEGRGRAVRDQLAAVGRNLIADDEAATALSVFDPVWEALNPREQARVVNLLVETVGYDGSRGKVTIRFRPAGVRTLARELADKREGMRA
>NZ_CP042425.1|WP_149114766.1|8622114_8622624_+|DUF2924-domain-containing-protein
MDPYPTIAQQLAALPRLTVKDLQRRYAEAFGDETAARNKAWLVKRIAWKLQANAHGGLTDRARQRAAELAAGAELRTTIPAKRATPAPVAAPAEPEAATLPFPADRRLPPPGSVLTRAYKGQTLQVRVLTHGFEHAGLVYPSLSAVAKAVTGSHCNGYLLFRLTNGGDA
>NZ_CP042425.1|WP_149114765.1|8621865_8622072_+|hypothetical-protein
MRPDLDPAHFSPDDRFRELAAILARGLIRLRDKVALTPRHTSAPQILPKSSDSSVAVHPDTWLTVHTG
>NZ_CP042425.1|WP_149114764.1|8620809_8621700_-|IS982-family-transposase
MTLNDFLLHVFVLVDDLYRQLVRTPLRSRGPRHTAMTDPEVITIELVGEFLGLDHDKGLFAHFRRYHAAEFPALAGVHRTTFARQAANLFAVKKQLHAHLAERLAVWDRVFIVDSLPVPACAFGRAKSCRRFAGDAAFGYDHTRRNTMYGFRFHARATPTGILVAFDLAPANVSDQAMVDPLGPPPGSAVVGDRNYWSPKAGARLAEQGVKLVAPFRSKSKDPGPRRSRRISRFRWIIETAFGQLAGRFHIERTWARDVWHLSHRVIRKVLGHTIAVWLNVTAGRPPLDFDGLVTD
>NZ_CP042425.1|WP_149114763.1|8620099_8620462_-|hypothetical-protein
MTSDRAEEERDEWCFEFNVSSERLVHQSEADRLLDEAIHWAGAHRLGVGGSYKPASAEVNNACVSWAFRFGLCASEDEQLIPRESASDLWDLLSAVCQHRGFICTGGFRAFTAEELGEGL
>NZ_CP042425.1|WP_149114762.1|8618878_8619892_-|PQQ-binding-like-beta-propeller-repeat-protein
MPASLNCRPPFWAVVLFLTATVPARADEALAFQGHTNEVNGVQSSPDGSRFATSSLDGTAKVWDAKTGKELLTLKGHTYYARAVAFSPDGTRVASTDGNGAAKVWDAKTGAELLTFKGHEVLRNVWSVAFSPDGTRAVTTSADSTARVWDAKTGAELLKIKGREKYLESAVFSPDGSRIVVGSWDWTAGVYDAKSGKELLPLQGHSGIVHGVAFSPDGKRIASAGQDGKAKVWDAATGKRLLTLEGHNKWLLSIAYSPDGLRLVTTSGDGTAKVWDAKTGDELFTVKGADKPVTAASFGPDATRLVTGYGDGWVRTWDLRTPTDSRPPQKVDAKPGK
>NZ_CP042425.1|WP_168219432.1|8628677_8629595_-|hypothetical-protein
MTDAGRATPKKRPLRRRVALLTVALLGAGLIAVEAYAISPSVRIAVADVWEGVGASGRLVGMLSDSDERVRAVASSALVRLGPAAIPACARGVEHPDPRVRKFALFTLGQLGPPAKIALASILNRATNDPEPDVRKAAIQALPNVVDENSAATTTLAGILASGDTDGRLAAVKALGHPKLQSADGVAALSRALKDPAAQVRRDAAESLAAFGPTAAVAVPALVDALRDPEADVRVEAAETLGSLSAFAKSAVPGLIAALKDPHPKVRSEAAEALEQITRDWGDGEPTLRQLALDALAQINREPAP
>NZ_CP042425.1|WP_168219433.1|8629591_8629861_-|hypothetical-protein
MRTIVIAVFAGLMAVVVAGCGEKKAAKTAMELKDVPPDILKVAKEKLPGVAFDAAYREANGSYELRGKEKGGKVREIDVKPDGTVEEVQ
>NZ_CP042425.1|WP_168219434.1|8629860_8630784_-|DUF1559-domain-containing-protein
MNTTRPRSRRGFTLIELLVVIAIIAILIGLLLPAVQKVREAAARSQCVNNLKQVGLALQNYHDANQKFPPGYVSAFDAAGNDTGPGWGWAAHVLPQMEQDNLYRQIDLKQPIEAAANASARVVIVKSFLCPYDAPPQQAIPVGPRSASAQLTSTTCTVAPANYIGNFGVNEPGVDGDGVFYRNSAVRIADVTDGTSSTLMVGERSFYYAEATWVGAVTGANLAPTPGSPLPVQTENASNFVLAHTGETYDGPANPKEINHYAARHTGGGNFVFADGHVAYLSRSTTYATYKALSTRATGEAINAGDY
>NZ_CP042425.1|WP_149114774.1|8630865_8632308_-|heavy-metal-sensor-histidine-kinase
MSSKNGPDARPEPRPAWPLAARLTAWYAGSAFLLVAAAVGFLYWVLARSLDRQDDNLIADQVRVVGDVLAERPGDLEAVRQEAEQEFQSRQHTQVYVRLIDAGGRTLVETPGMAKLLDPSGFPPPTADFRAGSNLRSATGTPFRVMAIRVGDGRPGGSEYVVQGAMDHGDEAALLAEYRRNLWLVLAAGLAVCVAVGHQIARRGLRPVRLVADTARRIGPTNFGERITADGLPADLLDLADTFNRMLDRLERSFTRLARFSADIAHELRTPVNNLRGEVEVALGQPRTPDQYRDLLASNLEECGRLARLIDNLLFLARAENPGTQVSKDRVEVGGELQTVCEFYEGMAGEKGVTLVVAVSGPVQVVVNRPLFQRAVCNLVENAIRHTPAGGEITLSAATAGGSGTVAVTDSGSGIPAADLPHVFDRFYRADPARSSEGRNVGLGLSIVKSITDLHGGSVSADSEAGRGTRVAMTFPLDAV
>NZ_CP042425.1|WP_149114775.1|8633525_8634734_+|ParB-N-terminal-domain-containing-protein
MLVELRDISSITPYADNPRINDPAVDAVAESLAAFGWRQPLVVDAASVIVVGHTRYKAALKLGLTVVPVHVATDLTPAQAKAYRLADNRTAAIATWDDGKLVAELLALQGTDVDLASIGFTADELADLLKADEPTVLGDPDAVPDPPADPVTRPGDVWLLGRHRLLCGDATKPADLAKVLDGAPADLLLTDPPYNVAYEGKTADKLTIANDAMAGGDYRRFLARALAAAKGVLRPGAAFYLWHADLEGLNVRAACGDAGLRVRQCLVWVKSAFALGRFDYHWKHEPCLYGWDDGAAHTWLSDRAQTTVLEFDRPAKNDVHPTMKPVGLFAYLIGNSCPPGGVVLDPFAGSGTTLVAAEHTGRTAALVELDPRYCDVIVKRYEDLTGGTAERIPAGDTVLAAV
>NZ_CP042425.1|WP_149114776.1|8634804_8635203_+|hypothetical-protein
MTTPRRATADDTLLLALACGATQEAAATKAGLGVTTVRRRLQDPDFVRRLRAVQADIVARTAGALTAAATESVRTLLDLQKPGSPPATRLGTARAVLELGLKVREVVELEARIASLEEQMDADFAPAAGGGM
>NZ_CP042425.1|WP_149114777.1|8635202_8635556_+|hypothetical-protein
MRTRSPVRRLERRLSAYIDATQPPLSDPEWLAVFRDAVARGWERRVPGFAAAVAAYRAAAEAAARVAPEVDPPTGFALRHPRRVPVLFTGRLDPRFPAVWAAFARACELYLRAEGVR
>NZ_CP042425.1|WP_149114778.1|8635552_8635786_+|hypothetical-protein
MRLRGRLDQLTNRVRSTRPDAPPLTVFLIEATVDRPVGTQSVWGGIAREICYDPTAGPPVLPPSGPHKIVFGPEFDV
>NZ_CP042425.1|WP_149114779.1|8635796_8636186_+|hypothetical-protein
MSQWNRVRRIEDGVRAAHPTAAPPGLVFVLEATADRPPGRWVRADGATVVLVYDPAGPEPDLRFPGNPLALGGIDPFACEPNAARDLRFVPTEPLRIGDARAGRLKPSSAKASARRTGQRRFGDGEGKG
>NZ_CP042425.1|WP_149114780.1|8636182_8636416_+|hypothetical-protein
MRIRSRLDRLTNRRRATRPGAPPLVIFLIEATVGQPVGTRVVWDGRAREVTFDPAAGPPPLPPGGPHKLIAGPAFDV

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Crispr_ID: NZ_CP042425_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042425_17

8640100-8640211

Orphan

Consensus_repeat	Method
CTGCTCCAACTTGTCGTGAGGATGACCCATGCGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042425_17

>merge|NZ_CP042425|17|8640100-8640211|CRISPRCasFinder
CTGCTCCAACTTGTCGTGAGGATGACCCATGCGCGTGTAGCCCGAAACCAGGGCATTGACGCCGTCTGCGGTCGGTCTGCTCCAACTTGTCGTGAGGATGACCCATGCGCGT

>NZ_CP042425|17|16|8640100-8640211|CRISPRCasFinder
CTGCTCCAACTTGTCGTGAGGATGACCCATGCGCGT	GTAGCCCGAAACCAGGGCATTGACGCCGTCTGCGGTCGGT
CTGCTCCAACTTGTCGTGAGGATGACCCATGCGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042425.1\|WP_149114790.1\|8642602_8644555_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|226951
NZ_CP042425.1\|WP_168219435.1\|8637334_8637505_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114787.1\|8640421_8640655_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225214
NZ_CP042425.1\|WP_149114793.1\|8650865_8651054_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114781.1\|8636772_8637225_+\|response-regulator	unknown	unknown	gnl\|CDD\|381118
NZ_CP042425.1\|WP_149114778.1\|8635552_8635786_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114791.1\|8646194_8648690_+\|magnesium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319772
NZ_CP042425.1\|WP_149114782.1\|8637699_8638005_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114780.1\|8636182_8636416_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114777.1\|8635202_8635556_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114783.1\|8638314_8638602_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114792.1\|8649378_8650614_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP042425.1\|WP_149114794.1\|8651135_8651603_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114796.1\|8652264_8652522_+\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|240668
NZ_CP042425.1\|WP_149114785.1\|8639513_8639942_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114795.1\|8651761_8652268_+\|response-regulator	unknown	unknown	gnl\|CDD\|381118
NZ_CP042425.1\|WP_149114784.1\|8638640_8638997_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042425.1\|WP_149114788.1\|8640741_8641755_-\|response-regulator	unknown	unknown	gnl\|CDD\|381118
NZ_CP042425.1\|WP_149114789.1\|8641959_8642625_-\|response-regulator	unknown	unknown	gnl\|CDD\|225107
NZ_CP042425.1\|WP_149114779.1\|8635796_8636186_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042425.1\|WP_149114796.1\|8652264_8652522_+\|RNA-binding-protein	gnl\|CDD\|240668	cd00590, RRM_SF, RNA recognition motif (RRM) superfamily. RRM, also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA processing, RNA export, and RNA stability. This domain is 90 amino acids in length and consists of a four-stranded beta-sheet packed against two alpha-helices. RRM usually interacts with ssRNA, but is also known to interact with ssDNA as well as proteins. RRM binds a variable number of nucleotides, ranging from two to eight. The active site includes three aromatic side-chains located within the conserved RNP1 and RNP2 motifs of the domain. The RRM domain is found in a variety heterogeneous nuclear ribonucleoproteins (hnRNPs), proteins implicated in regulation of alternative splicing, and protein components of small nuclear ribonucleoproteins (snRNPs).	1.67092e-10
NZ_CP042425.1\|WP_149114790.1\|8642602_8644555_-\|PAS-domain-S-box-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.52063e-44
NZ_CP042425.1\|WP_149114787.1\|8640421_8640655_+\|hypothetical-protein	gnl\|CDD\|225214	COG2335, COG2335, Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane].	8.25298e-10
NZ_CP042425.1\|WP_149114795.1\|8651761_8652268_+\|response-regulator	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.50114e-19
NZ_CP042425.1\|WP_149114781.1\|8636772_8637225_+\|response-regulator	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.27373e-09
NZ_CP042425.1\|WP_149114791.1\|8646194_8648690_+\|magnesium-translocating-P-type-ATPase	gnl\|CDD\|319772	cd02077, P-type_ATPase_Mg, magnesium transporting ATPase (MgtA), similar to Escherichia coli MgtA and Salmonella typhimurium MgtA. MgtA is a membrane protein which actively transports Mg(2+) into the cytosol with its electro-chemical gradient rather than against the gradient as other cation transporters do. It may act both as a transporter and as a sensor for Mg(2+). In Salmonella typhimurium and Escherichia coli, the two-component system PhoQ/PhoP regulates the transcription of the mgtA gene by sensing Mg(2+) concentrations in the periplasm. MgtA is activated by cardiolipin and it highly sensitive to free magnesium in vitro. It consists of a transmembrane domain and three cytosolic domains: nucleotide-binding domain, phosphorylation domain and actuator domain, and belongs to the P-type ATPase type III subfamily. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP042425.1\|WP_149114788.1\|8640741_8641755_-\|response-regulator	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.71851e-27
NZ_CP042425.1\|WP_149114789.1\|8641959_8642625_-\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.82047e-73
NZ_CP042425.1\|WP_149114792.1\|8649378_8650614_-\|acetate/propionate-family-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	3.86798e-151

>NZ_CP042425.1|WP_149114785.1|8639513_8639942_+|hypothetical-protein
MATKNDGATGRHLLVVLDHHEAKVYQAEVHGAVPQRIVPYDPSGYGRHLHSANEWTDGKRQPERQSFYEAIAKTLAGADQVLLFGSGTGKSSAMEQLLADLTRHHAEVAKRVIGAVVVDAHHATEDQLLAHARDFYTEFNRR
>NZ_CP042425.1|WP_149114784.1|8638640_8638997_+|hypothetical-protein
MSNLNRIVAHIRIRNRQDVPAKYVRRYNSLSAAARKSIRGGDVILLREMAKRFSYVHIIGGDIVTFGPRATKRVVAKLERMGLYAVVEFGRVRVNAGGEVIVTENVSQKRYAATIAGA
>NZ_CP042425.1|WP_149114783.1|8638314_8638602_+|hypothetical-protein
MPKNKLPRLTLVDAEASQSLIGPVESLRNQILVTMGRPRDLIRIDVINLWPNTYRANVIVGPSLDRARFAHSYFVTTTDGGKVVTSTPGLNCVYS
>NZ_CP042425.1|WP_149114782.1|8637699_8638005_+|hypothetical-protein
MTNNTALTRQQVAMTTTDSSDTDLQQMSDDGYPHSPDPTRAFGAGDSASTPVAAERRRDDGYDPGMGAGDEWGGFLYHLPSGAERSGAEGPGLPIPRQPST
>NZ_CP042425.1|WP_168219435.1|8637334_8637505_+|hypothetical-protein
MTRSPPGARFVDLAPGGASAVAALDGATYRGAALIVRDLWEAVTINGEAPGRWPDT
>NZ_CP042425.1|WP_149114781.1|8636772_8637225_+|response-regulator
MTTPLPRRLKVLVADPSRDGADSLADLTRLYGCRATTAYTTSETVVLLHTRRFDIAFIDPALLGVSMGQVIGHALAPSREVRPFVIAVSECPSEEWCGEGLSAGVNLYLTKPLPPGLIGGLLRRLQPFIYAMELPADLALIVGHTQKVSS
>NZ_CP042425.1|WP_149114780.1|8636182_8636416_+|hypothetical-protein
MRIRSRLDRLTNRRRATRPGAPPLVIFLIEATVGQPVGTRVVWDGRAREVTFDPAAGPPPLPPGGPHKLIAGPAFDV
>NZ_CP042425.1|WP_149114779.1|8635796_8636186_+|hypothetical-protein
MSQWNRVRRIEDGVRAAHPTAAPPGLVFVLEATADRPPGRWVRADGATVVLVYDPAGPEPDLRFPGNPLALGGIDPFACEPNAARDLRFVPTEPLRIGDARAGRLKPSSAKASARRTGQRRFGDGEGKG
>NZ_CP042425.1|WP_149114778.1|8635552_8635786_+|hypothetical-protein
MRLRGRLDQLTNRVRSTRPDAPPLTVFLIEATVDRPVGTQSVWGGIAREICYDPTAGPPVLPPSGPHKIVFGPEFDV
>NZ_CP042425.1|WP_149114777.1|8635202_8635556_+|hypothetical-protein
MRTRSPVRRLERRLSAYIDATQPPLSDPEWLAVFRDAVARGWERRVPGFAAAVAAYRAAAEAAARVAPEVDPPTGFALRHPRRVPVLFTGRLDPRFPAVWAAFARACELYLRAEGVR
>NZ_CP042425.1|WP_149114787.1|8640421_8640655_+|hypothetical-protein
MLADKEQLKTVLMANPVVGKAVLAADALKMDRKEVNGLKVCVDGTAVNVGDARVILTDIKAGNGVIHTTGAVLMPKD
>NZ_CP042425.1|WP_149114788.1|8640741_8641755_-|response-regulator
MKGPLPYVLVVDDLRDTADSTADLLALWGYDAAPYYDGDSALAAAARRPPDVVLLDIGMAPMNGFVFAARLRGVPGCERTGVVIVSGYTSQEYRARARDLGAGHFLPKPTDPNALRALVARLVTPRLTPVRRNPSAAEEDSVGPAPAAPMNRPRQTRFEDLRLMNPPTATALRPYGRGDPGPSSVPALVRNGPERPVGILVVDDDDGIRAVLAAGLERHGFSVWPAADGREAVAHHRVHHASIDLALLDVLMPGRDGPETLHHLRQFAPHLSACFMTADAGRYTERDLFALGPLAVFRKPFDVVDMAGRLAGLVADVAAAKPGCRNAGRSGRPGLGE
>NZ_CP042425.1|WP_149114789.1|8641959_8642625_-|response-regulator
MEEPTVAKIRVYLADDHAVVREGLKVLINAQADMTVVGEAANGLLACEQIPALLPDVVVMDVTMPALTGSQATTRIRRECPTARVLALTLHEDKGYIRQLLAAGAVGYVLKRAAPEELIHAIRAVAAGGTYLDPSMAGKVVGGFVRQPANVDLPHGSLSEREAAVAHQTAAGHSNKEIAARLELSVKTVETYRARAMEKLGLQSRADLVRYAVQQGWLQGG
>NZ_CP042425.1|WP_149114790.1|8642602_8644555_-|PAS-domain-S-box-protein
MASEQNARQPLAEWVQSALVGIGLGLIVTDDKARILAVNPVAASLTGWSADDAVSRTAEAVFRIEDEVTRRPAPDPVTDVLAGGVAVGLSDHTVLIGRGGSECRIDHGASPVWDAAGAIIGAVLLFCDVSERQRAVQGVEDARAFAEGIIQTVREPLVVLDAGLRVRSANSSFYRTFRVTAPETEGQTLFALGNRQWDIPQLREQLEAILTGDHHFENFAVDHVFDGIGRRSMVLNARRLLLPGRQSGLVLLAIEDATERVRATESLALSETRYRRLFETAQDGILLVDPETRRIFDANPFLTDLLGHPWVELIGKELWEIGLFDDIESNKAAFRTLQETGYIRYDDLPLRTHDGRGIEVEFVSNVYPVGDTPVIQCNIRDVTDRKRAEVALQAAHDGLEVRVAERTAELAHTNATLSDEIGRREIAEADRRDLQQRLTTVQEDERRRIARELHDQMGQHLTALGLGLKVVRDATAHPSQEWDRLHALQSLTDLIGREVHDLALELRPTALDDLGLSAALAHYTDGWAERTGVEVDYHGPEADENRLGAEVETALYRVVQEALMNVHKHAAARRVSVVFRRSPEDVSVLIEDDGRGFDADAQALHRLGILGMRERMALMGGTLTLESAPGRSTVIARVRPTPRDGGTHRG
>NZ_CP042425.1|WP_149114791.1|8646194_8648690_+|magnesium-translocating-P-type-ATPase
MASVTSPSPEGLTTAEARSRLDEHGPNEITPTAGPGGVKQLLITFLNPLTVILLVAGGVAAGVGDYATAAVIGVVVGVSSLIQFFHTLRSDQALRHLQDRVAVTATVRRDGVWAERPRRDVVPGDLIRLAAGDFIPADARLVTARDLHVLQAALTGESLPVEKEVRENSGKPGDPLALDRPDAVFFGTSVVSGTGTAVVAATGRATAFGDVAARLAAKAPETEFDRGTRRFGLFITQTVFALVVFVFVVAVARQLPAMESLLFALALAVGLTPGLLPMIVNVTLARGAVRMARQDVIVKHLAAIQNLGSMDVLCTDKTGTLTRGDVSLVRCDTAAGVSADRVLLLAYLNSRHETGFKNPLDVAILAHPVPAGVEGFEKLDEVPFDFERRRLSVVLRGPSGVTLVTKGAPESVLDCCGSWEDGPETRPLDAATRDRVLAYVRRQSVEGYRLLAVASRVVTPGGRYSAADEVELTLAGFLAFTDPIREDAADAIRDLAADGVRVVMISGDDEHVARRIADLVGLGGGRVVSGGELAGMTDPALGAVAEQVAVFARTSPAQKNRILLALKARGHVVGFLGDGVNDAPSIHAADVGISVSTAVDVAKAAAEVILMKPGLRVIHDGVLEGRRAFTNVMKYLLMGTSSNFGNMLSMAAAVVFLPFLPMLPLQILLNNLLYDLAQLPIPTDRVDAALVRKPRKWDVSAIRTFMLVVGPVSSAFDLVTFAGLVWLFHATATAFQTGWFVESLFTQTLVVLVIRTAGNPFRSRPSPWVLGTVIGVCGVAVALPFTPVAGPLGFEPLPGAFVPFLLAVAAAYLLAVEVVKRRFFRDVAARA
>NZ_CP042425.1|WP_149114792.1|8649378_8650614_-|acetate/propionate-family-kinase
MDTPHDTPPASTPRGGCVLTINGGSSSIKFALFGPAAGGDRLFAGAVERVGTPEASLRAAGLGDREDRKPIAATDPARAADELIDWLEERGDLAGVAAVGHRVVHGGPDHAEPRVIDAALLADLRRLVPLDPDHLPAELALKDALTRRRPTLPQVACFDTAFHHALPPVARVLPIPRRYGIRRYGFHGLSYAYLVEELRRVAGPTAPDGRLILAHLGSGASLAAVRGGACVDTTMRFTPAGGLVMGTRTGDLDPGVLIHLTRTENLTADQLDAVVNRESGLRGISETSSDMRDLLAREATDSRAADAVALFCYQAKKFIGAMAAALGGVDTLVFAGGVGENSPEVRSRICDGLAFLGVDLGLASNAANAAVISSGITGVTVRVIRTDEEVLIARTTACVLGLPFQQKDATP
>NZ_CP042425.1|WP_149114793.1|8650865_8651054_+|hypothetical-protein
MAGTIKGKVEDLGQAAKDAAKKAGEKVKDGAEVDAEKTAHAAKTVGQAAKDAGQKAKDKSEG
>NZ_CP042425.1|WP_149114794.1|8651135_8651603_-|hypothetical-protein
MRRLTLAVSLLVIALTCGCGSTEPHAVAEVAVAPDRTLVRVMVDLYAANPAKAYAAYRDRPQPVTGIVPRKIEQLPEFRTVYKVACDLDGKRPEKDPAFYVYCTEREAAGWAVGTAGSAVLMLRQSDRNDVRPVFITPAGAVAMGEESRSRQRGN
>NZ_CP042425.1|WP_149114795.1|8651761_8652268_+|response-regulator
MTTPTLRPLSTLVVDNSRDAADSLADLLRLYGHQAAATYSGSQAVAVLGDRPVDVVLIDPAMPGLVGNALLRRVAAASPRKRPFVVVTTGSSDDHDRDDWRAAGADLVLMKPLPEGLVGGLLRRIRHFLDTLGPPTDEPGIAGPAGGTDARCDIRSSPPRRLPGKVSS
>NZ_CP042425.1|WP_149114796.1|8652264_8652522_+|RNA-binding-protein
MMSLRVNNLPAGATVADLWELFHPFGRVAWAAIRGIPLPKGDPPGVGYVDLATGGAAAICALDGSDYRGRRLAVREADLNDLEAG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP042425_16	16.1\|8628276\|43\|NZ_CP042425\|CRISPRCasFinder	8628276-8628318	43	NZ_CP042425.1	8703863-8703905	0	1.0

1. spacer 16.1|8628276|43|NZ_CP042425|CRISPRCasFinder matches to position: 8703863-8703905, mismatch: 0, identity: 1.0

tcaggtgaggcgccggaagcgaacagccggggggctcacgcgg	CRISPR spacer
tcaggtgaggcgccggaagcgaacagccggggggctcacgcgg	Protospacer
*******************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	432757-432784	3	0.893
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	397821-397848	3	0.893
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP017942	Phyllobacterium zundukense strain Tri-48 plasmid unnamed3, complete sequence	514896-514923	3	0.893
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	313253-313280	4	0.857
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	NZ_LR134452	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence	189743-189770	4	0.857
NZ_CP042425_10	10.1\|4379949\|26\|NZ_CP042425\|CRISPRCasFinder	4379949-4379974	26	NZ_AP018285	Chondrocystis sp. NIES-4102 plasmid plasmid4 DNA, complete genome	14996-15021	4	0.846
NZ_CP042425_7	7.2\|3933898\|28\|NZ_CP042425\|CRISPRCasFinder	3933898-3933925	28	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	15858-15885	5	0.821
NZ_CP042425_7	7.2\|3933898\|28\|NZ_CP042425\|CRISPRCasFinder	3933898-3933925	28	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	16602-16629	5	0.821
NZ_CP042425_7	7.2\|3933898\|28\|NZ_CP042425\|CRISPRCasFinder	3933898-3933925	28	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	17346-17373	5	0.821
NZ_CP042425_7	7.2\|3933898\|28\|NZ_CP042425\|CRISPRCasFinder	3933898-3933925	28	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	18090-18117	5	0.821
NZ_CP042425_7	7.2\|3933898\|28\|NZ_CP042425\|CRISPRCasFinder	3933898-3933925	28	NZ_CP014361	Methylomonas sp. DH-1 plasmid, complete sequence	18834-18861	5	0.821
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	680205-680232	5	0.821
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	NZ_MF600313	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_1, complete sequence	107311-107338	5	0.821
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	388684-388711	5	0.821
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_AP022578	Mycolicibacterium aubagnense strain JCM 15296 plasmid pJCM15296, complete sequence	142288-142315	5	0.821
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP015747	Shinella sp. HZN7 plasmid pShin-11, complete sequence	72495-72522	5	0.821
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	CP003951	Rhodococcus opacus PD630 plasmid 2, complete sequence	12417-12444	5	0.821
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP015094	Pelagibaca abyssi strain JLT2014 plasmid pPABY6, complete sequence	35630-35657	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP007257	Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence	168431-168458	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP010862	Marinovum algicola DG 898 plasmid pMaD7	84314-84341	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP020701	Streptomyces tsukubensis strain NRRL 18488 plasmid pSTS1, complete sequence	6224-6251	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NC_010116	Pseudomonas phage YuA, complete genome	25061-25088	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NC_028980	Pseudomonas phage PAE1, complete genome	54173-54200	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	MF490239	Pseudomonas phage vB_PaeS_S218, complete genome	34259-34286	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	MF417932	Uncultured Caudovirales phage clone 3S_12, partial genome	17734-17761	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP020810	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed1, complete sequence	304-331	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	MN871482	UNVERIFIED: Pseudomonas virus PaSz-6, complete genome	29290-29317	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	MH791403	UNVERIFIED: Pseudomonas phage PaTs-2, complete genome	27468-27495	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	MN871478	UNVERIFIED: Pseudomonas phage PaSt-2_45_61k, complete genome	27468-27495	6	0.786
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	MT118302	Pseudomonas phage Epa38, complete genome	966-993	6	0.786
NZ_CP042425_8	8.1\|3934468\|28\|NZ_CP042425\|CRISPRCasFinder	3934468-3934495	28	JX182371	Streptomyces phage SV1, complete genome	24849-24876	7	0.75
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1234059-1234086	7	0.75
NZ_CP042425_8	8.2\|3934522\|28\|NZ_CP042425\|CRISPRCasFinder	3934522-3934549	28	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1243530-1243557	7	0.75

1. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 3, identity: 0.893

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
ccagcccctcggtcccccggccgccgac	Protospacer
 **** * ********************

2. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 3, identity: 0.893

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
ccagcccctcggtcccccggccgccgac	Protospacer
 **** * ********************

3. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP017942 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.893

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
ggaggacatcgttaccgtcgtcgccgtt	Protospacer
***********.********.***** *

4. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 4, identity: 0.857

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
caagcccctcggtcccccggccgccgac	Protospacer
  *** * ********************

5. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to NZ_LR134452 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence) position: , mismatch: 4, identity: 0.857

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
tccgcacggcggtcccccggccgccgtc	Protospacer
 * ***** ***************** *

6. spacer 10.1|4379949|26|NZ_CP042425|CRISPRCasFinder matches to NZ_AP018285 (Chondrocystis sp. NIES-4102 plasmid plasmid4 DNA, complete genome) position: , mismatch: 4, identity: 0.846

acctgtttcgagcccattttgactgt	CRISPR spacer
acctgtttcaagccaattttgacggg	Protospacer
*********.**** ******** *

7. spacer 7.2|3933898|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.821

acagcacgtcggcaccctgactgccctg	CRISPR spacer
tcagcacgtcggcaccttgaccgcccaa	Protospacer
 ***************.****.**** .

8. spacer 7.2|3933898|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.821

acagcacgtcggcaccctgactgccctg	CRISPR spacer
tcagcacgtcggcaccttgaccgcccaa	Protospacer
 ***************.****.**** .

9. spacer 7.2|3933898|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.821

acagcacgtcggcaccctgactgccctg	CRISPR spacer
tcagcacgtcggcaccttgaccgcccaa	Protospacer
 ***************.****.**** .

10. spacer 7.2|3933898|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.821

acagcacgtcggcaccctgactgccctg	CRISPR spacer
tcagcacgtcggcaccttgaccgcccaa	Protospacer
 ***************.****.**** .

11. spacer 7.2|3933898|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP014361 (Methylomonas sp. DH-1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.821

acagcacgtcggcaccctgactgccctg	CRISPR spacer
tcagcacgtcggcaccttgaccgcccaa	Protospacer
 ***************.****.**** .

12. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 5, identity: 0.821

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
tccacacgtcggtccaccggtcgccgac	Protospacer
 * .*********** ****.*******

13. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to NZ_MF600313 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_1, complete sequence) position: , mismatch: 5, identity: 0.821

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
gcagcacgtcgatcccccggacggagtc	Protospacer
***********.******** **  * *

14. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 5, identity: 0.821

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cggggacatcgccaccgtcgccaccgac	Protospacer
 *.*********.*********.****.

15. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_AP022578 (Mycolicibacterium aubagnense strain JCM 15296 plasmid pJCM15296, complete sequence) position: , mismatch: 5, identity: 0.821

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
gctggcgatcgctaccgtcgccgccgaa	Protospacer
*  **  ********************

16. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP015747 (Shinella sp. HZN7 plasmid pShin-11, complete sequence) position: , mismatch: 5, identity: 0.821

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgccgacatcgtgaccgtcgccgccgat	Protospacer
 *  *******. ***************

17. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to CP003951 (Rhodococcus opacus PD630 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.821

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
caacgacatcggtaccgtcgccggcgat	Protospacer
 .* ******* *********** ****

18. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP015094 (Pelagibaca abyssi strain JLT2014 plasmid pPABY6, complete sequence) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
gcaccacatcggtaccgtcgccgccgtc	Protospacer
* *  ****** ************** .

19. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP007257 (Rhodococcus erythropolis R138 plasmid pLRE138, complete sequence) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgtggacatcgacaccgtcgccgccgtc	Protospacer
 * ******** .************* .

20. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP010862 (Marinovum algicola DG 898 plasmid pMaD7) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
ggaggacatcgccaccgccgccggctgg	Protospacer
************.****.***** * .

21. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP020701 (Streptomyces tsukubensis strain NRRL 18488 plasmid pSTS1, complete sequence) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
gccggacatcgccgccgtcgccgccgcg	Protospacer
*  *********..************

22. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NC_010116 (Pseudomonas phage YuA, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

23. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NC_028980 (Pseudomonas phage PAE1, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

24. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to MF490239 (Pseudomonas phage vB_PaeS_S218, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

25. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to MF417932 (Uncultured Caudovirales phage clone 3S_12, partial genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
gcaggacatcgaaaccgtcgccgccatg	Protospacer
* *********  ************.

26. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP020810 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
agaggccatcgttaccgtcgccgcggga	Protospacer
.**** *****.************ *.

27. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to MN871482 (UNVERIFIED: Pseudomonas virus PaSz-6, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

28. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to MH791403 (UNVERIFIED: Pseudomonas phage PaTs-2, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

29. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to MN871478 (UNVERIFIED: Pseudomonas phage PaSt-2_45_61k, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

30. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to MT118302 (Pseudomonas phage Epa38, complete genome) position: , mismatch: 6, identity: 0.786

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
cgcgggcctcgctaccgtcgccgccgtc	Protospacer
 * **.* ****************** .

31. spacer 8.1|3934468|28|NZ_CP042425|CRISPRCasFinder matches to JX182371 (Streptomyces phage SV1, complete genome) position: , mismatch: 7, identity: 0.75

gcagcacgtcggtcccccggccgccgac	CRISPR spacer
ccccgtcgtcgttcccccggccgccgaa	Protospacer
 *    ***** ***************

32. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 7, identity: 0.75

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
tcgccacatcgctgccgtcgccgccggt	Protospacer
  .  ********.************.*

33. spacer 8.2|3934522|28|NZ_CP042425|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.75

ggaggacatcgctaccgtcgccgccgat	CRISPR spacer
tcgccacatcgctgccgtcgccgccggt	Protospacer
  .  ********.************.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

861709 : 920755

uncultured_Mediterranean_phage(28.57%)

transposase,tRNA,protease,tail,capsid,head

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149108764.1\|861709_862129_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_149108765.1\|862187_862613_-	PRC-barrel domain containing protein	NA	NA	NA	NA
WP_149108766.1\|862927_864262_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_149108767.1\|864372_865491_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	8.8e-88	48.0
WP_149108768.1\|865592_867020_-	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	4.1e-13	25.0
WP_149108769.1\|867293_867608_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_149108770.1\|867778_870073_+	DUF1343 domain-containing protein	G3M511	Mycobacterium_phage	2.9e-08	27.1
WP_149108771.1\|870105_873024_-	FAD-binding protein	NA	NA	NA	NA
WP_149108772.1\|873211_873721_+	hypothetical protein	NA	NA	NA	NA
WP_149108773.1\|873809_874796_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	1.6e-48	34.2
WP_149115410.1\|874837_876049_-	DUF5009 domain-containing protein	NA	NA	NA	NA
WP_149108774.1\|876223_877243_-	porphobilinogen synthase	NA	NA	NA	NA
WP_149108775.1\|877468_878872_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_149108776.1\|878894_879383_+	hypothetical protein	NA	NA	NA	NA
WP_149108777.1\|879392_879629_+	hypothetical protein	NA	NA	NA	NA
WP_149108778.1\|879633_880569_-	c-type cytochrome	NA	NA	NA	NA
WP_149108779.1\|880638_880860_-	hypothetical protein	NA	NA	NA	NA
WP_149108780.1\|881003_882443_-	BBP7 family outer membrane beta-barrel protein	NA	NA	NA	NA
WP_149108781.1\|882923_889043_+	hypothetical protein	NA	NA	NA	NA
WP_149108782.1\|889130_890330_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_149108783.1\|890460_891372_+	formylmethanofuran--tetrahydromethanopterin N-formyltransferase	NA	NA	NA	NA
WP_149115411.1\|891372_892179_-	UbiA family prenyltransferase	NA	NA	NA	NA
WP_149108784.1\|892282_893662_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_149108785.1\|893710_893989_-	hypothetical protein	NA	NA	NA	NA
WP_149108786.1\|894068_894338_-	hypothetical protein	NA	NA	NA	NA
WP_149108787.1\|894442_895426_-	AAA domain-containing protein	NA	NA	NA	NA
WP_149108788.1\|896195_896519_-	hypothetical protein	NA	NA	NA	NA
WP_168218788.1\|896550_897183_-	SOS response-associated peptidase	S5W9X9	Leptospira_phage	1.4e-05	27.7
WP_149108790.1\|897280_898422_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149108791.1\|898480_898942_-	hypothetical protein	NA	NA	NA	NA
WP_149108792.1\|899215_900937_-	hypothetical protein	NA	NA	NA	NA
WP_149108793.1\|901031_902042_-	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_149115412.1\|902875_903121_-	hypothetical protein	NA	NA	NA	NA
WP_149108794.1\|903686_904811_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_149108795.1\|904811_905366_+	hypothetical protein	NA	NA	NA	NA
WP_149108796.1\|905746_906064_+	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_149108797.1\|906064_906475_-	four helix bundle protein	NA	NA	NA	NA
WP_149108798.1\|906503_906932_-	hypothetical protein	NA	NA	NA	NA
WP_149108799.1\|907560_908841_+	hypothetical protein	NA	NA	NA	NA
WP_149108800.1\|909412_910360_-	hypothetical protein	NA	NA	NA	NA
WP_149108801.1\|910356_911955_-	hypothetical protein	NA	NA	NA	NA
WP_149108802.1\|911961_912870_-	hypothetical protein	NA	NA	NA	NA
WP_149108803.1\|913621_914995_-	hypothetical protein	NA	NA	NA	NA
WP_149108804.1\|914998_915307_-	hypothetical protein	NA	NA	NA	NA
WP_149108805.1\|915327_915531_-	hypothetical protein	NA	NA	NA	NA
WP_149108806.1\|915622_916063_-	hypothetical protein	NA	NA	NA	NA
WP_149108807.1\|916099_916774_-	hypothetical protein	NA	NA	NA	NA
WP_149108808.1\|916773_917103_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_149108809.1\|917102_917660_-	hypothetical protein	NA	NA	NA	NA
WP_149108810.1\|917746_919018_-\|capsid	phage major capsid protein	Q6DMU0	Streptococcus_phage	2.9e-26	26.6
WP_149108811.1\|919058_919598_-\|head,protease	HK97 family phage prohead protease	Q8SBP9	Clostridium_phage	1.7e-20	41.5
WP_149108790.1\|919613_920755_-\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1141223 : 1219589

Moloney_murine_sarcoma_virus(16.67%)

integrase,transposase,protease

attL 1198005:1198027|attR 1222572:1222594

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168218799.1\|1141223_1141664_-\|transposase	transposase	NA	NA	NA	NA
WP_149115418.1\|1142158_1143520_+	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_149115419.1\|1143582_1145103_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_149108988.1\|1145158_1145626_+	hypothetical protein	NA	NA	NA	NA
WP_168218800.1\|1145771_1147211_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_149108990.1\|1147215_1150329_+	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
WP_168218801.1\|1150536_1152123_-	TolC family protein	NA	NA	NA	NA
WP_149108992.1\|1152564_1153791_+	hypothetical protein	NA	NA	NA	NA
WP_149108993.1\|1153807_1156033_+	hypothetical protein	NA	NA	NA	NA
WP_149108994.1\|1156051_1157227_+	hypothetical protein	NA	NA	NA	NA
WP_149108995.1\|1157245_1158541_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_149108996.1\|1158668_1159904_+	protein kinase	Q85453	Moloney_murine_sarcoma_virus	5.6e-11	27.2
WP_149108997.1\|1159927_1160962_-	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_149108998.1\|1161673_1164811_+	DUF11 domain-containing protein	NA	NA	NA	NA
WP_168218802.1\|1164896_1166099_+	DUF4331 domain-containing protein	NA	NA	NA	NA
WP_149109000.1\|1166196_1167765_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_149109001.1\|1167945_1168395_-	hypothetical protein	NA	NA	NA	NA
WP_149109002.1\|1168391_1169180_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149109003.1\|1169395_1171486_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_149109004.1\|1171495_1172776_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_149109005.1\|1173690_1175994_-	hypothetical protein	NA	NA	NA	NA
WP_168218803.1\|1176254_1177922_+	hypothetical protein	NA	NA	NA	NA
WP_149109006.1\|1177937_1178576_-	FMN-binding negative transcriptional regulator	NA	NA	NA	NA
WP_149109007.1\|1178614_1178869_-	hypothetical protein	NA	NA	NA	NA
WP_149109008.1\|1178968_1180414_+	hypothetical protein	Q8QKV7	Ectocarpus_siliculosus_virus	4.4e-07	31.0
WP_149109009.1\|1180391_1181852_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_149109010.1\|1182125_1182542_+	hypothetical protein	NA	NA	NA	NA
WP_149109011.1\|1182541_1183918_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_149109012.1\|1183945_1187464_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_149109013.1\|1187979_1198323_+	DUF11 domain-containing protein	NA	NA	NA	NA
1198005:1198027	attL	NA	NA	NA	NA
WP_149109014.1\|1198393_1200292_-	protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	2.4e-16	25.3
WP_149109015.1\|1200481_1200859_+	hypothetical protein	NA	NA	NA	NA
WP_149109016.1\|1200855_1201878_-	WD40 repeat domain-containing protein	NA	NA	NA	NA
WP_149109017.1\|1201971_1203033_-	GTP-binding protein	NA	NA	NA	NA
WP_149109018.1\|1203134_1204559_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_149109019.1\|1204562_1205285_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.7e-36	41.0
WP_149109020.1\|1205374_1207291_-	hypothetical protein	NA	NA	NA	NA
WP_149109021.1\|1207250_1209902_-	hypothetical protein	NA	NA	NA	NA
WP_149109022.1\|1210144_1210528_+	hypothetical protein	NA	NA	NA	NA
WP_149109023.1\|1211145_1213239_-	hypothetical protein	NA	NA	NA	NA
WP_149109024.1\|1213862_1214159_+\|transposase	transposase	NA	NA	NA	NA
WP_168218804.1\|1214155_1215025_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	6.0e-52	38.2
WP_149109026.1\|1215877_1216384_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149109027.1\|1216526_1216895_+	hypothetical protein	NA	NA	NA	NA
WP_149109028.1\|1216891_1217473_+\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	6.7e-07	24.4
WP_149109029.1\|1217543_1218080_+	hypothetical protein	NA	NA	NA	NA
WP_149109030.1\|1218234_1218447_+	hypothetical protein	NA	NA	NA	NA
WP_149109031.1\|1218443_1219589_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1222572:1222594	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1253323 : 1286348

Bacillus_phage(60.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168218808.1\|1253323_1254451_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149109056.1\|1254593_1254917_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_168218808.1\|1255114_1256243_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_168218809.1\|1256746_1257178_-	DUF2262 domain-containing protein	NA	NA	NA	NA
WP_149109058.1\|1258227_1259397_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149108978.1\|1259458_1259713_-	hypothetical protein	NA	NA	NA	NA
WP_149109059.1\|1260194_1260551_+	hypothetical protein	NA	NA	NA	NA
WP_168218810.1\|1260597_1261050_+	GAF domain-containing protein	NA	NA	NA	NA
WP_149109061.1\|1261233_1261458_+	hypothetical protein	NA	NA	NA	NA
WP_149109062.1\|1261628_1262195_-	hypothetical protein	NA	NA	NA	NA
WP_149109063.1\|1262345_1262768_-	hypothetical protein	NA	NA	NA	NA
WP_149109064.1\|1262788_1264348_-	hypothetical protein	NA	NA	NA	NA
WP_149109065.1\|1264684_1264951_-	hypothetical protein	NA	NA	NA	NA
WP_149109066.1\|1265145_1265367_-	hypothetical protein	NA	NA	NA	NA
WP_149109067.1\|1265619_1265970_-	hypothetical protein	NA	NA	NA	NA
WP_149109068.1\|1266194_1266926_+	hypothetical protein	NA	NA	NA	NA
WP_149109069.1\|1266978_1267290_-	hypothetical protein	NA	NA	NA	NA
WP_168218811.1\|1267303_1267615_-	hypothetical protein	NA	NA	NA	NA
WP_149109071.1\|1267975_1268710_-	hypothetical protein	A0A1B0XUG0	Freshwater_phage	6.5e-07	23.6
WP_149109072.1\|1269103_1276858_+	hypothetical protein	NA	NA	NA	NA
WP_149109073.1\|1276880_1277297_+	hypothetical protein	NA	NA	NA	NA
WP_149109074.1\|1277566_1277917_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	6.0e-19	47.3
WP_168218812.1\|1279268_1279646_+\|transposase	transposase	NA	NA	NA	NA
WP_149109077.1\|1279778_1280912_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168218813.1\|1280950_1281175_+\|transposase	transposase domain-containing protein	NA	NA	NA	NA
WP_149109079.1\|1281834_1282176_-	DUF4259 domain-containing protein	NA	NA	NA	NA
WP_149109080.1\|1282349_1283108_-	hypothetical protein	NA	NA	NA	NA
WP_149109081.1\|1283710_1283902_+	hypothetical protein	NA	NA	NA	NA
WP_149109082.1\|1283964_1284405_+	hypothetical protein	NA	NA	NA	NA
WP_149109083.1\|1284741_1285086_-	hypothetical protein	NA	NA	NA	NA
WP_168218808.1\|1285220_1286348_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8

DBSCAN-SWA_4

1380884 : 1400010

Halovirus(100.0%)

integrase,transposase

attL 1398089:1398105|attR 1414206:1414222

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149108426.1\|1380884_1381364_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_168218822.1\|1381306_1381714_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_149109166.1\|1381909_1383142_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_168218823.1\|1384695_1385301_-\|transposase	transposase	NA	NA	NA	NA
WP_149109168.1\|1385198_1385732_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149109169.1\|1386127_1386487_+	hypothetical protein	NA	NA	NA	NA
WP_168218824.1\|1386665_1387664_+	hypothetical protein	NA	NA	NA	NA
WP_149109171.1\|1387798_1388524_+	hypothetical protein	NA	NA	NA	NA
WP_149109172.1\|1388523_1389231_+	hypothetical protein	NA	NA	NA	NA
WP_149109173.1\|1389303_1389546_+	hypothetical protein	NA	NA	NA	NA
WP_149109174.1\|1389631_1390195_+	hypothetical protein	NA	NA	NA	NA
WP_149109175.1\|1390829_1391090_+	hypothetical protein	NA	NA	NA	NA
WP_149109176.1\|1391121_1391412_+	hypothetical protein	NA	NA	NA	NA
WP_149115423.1\|1392113_1392386_+	hypothetical protein	NA	NA	NA	NA
WP_149109177.1\|1393060_1393639_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_149109178.1\|1393647_1394325_+	hypothetical protein	NA	NA	NA	NA
WP_149109179.1\|1395550_1395919_+	hypothetical protein	NA	NA	NA	NA
WP_149109180.1\|1395957_1397016_+	hypothetical protein	NA	NA	NA	NA
WP_149109181.1\|1397085_1397541_+	hypothetical protein	NA	NA	NA	NA
WP_149109183.1\|1397744_1398551_+	hypothetical protein	NA	NA	NA	NA
1398089:1398105	attL	NA	NA	NA	NA
WP_149109184.1\|1398628_1399129_+	HNH endonuclease	L7TJ57	Halovirus	2.7e-20	41.3
WP_168218825.1\|1399125_1400010_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1414206:1414222	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1900303 : 1965545

Bacillus_phage(16.67%)

transposase,protease,tRNA,integrase,tail

attL 1909420:1909437|attR 1960182:1960199

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149109572.1\|1900303_1901314_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_149109573.1\|1901276_1902020_-	hypothetical protein	A0A1X6WFU4	Pacmanvirus	1.1e-17	31.8
WP_149109574.1\|1902016_1902910_-	DedA family protein	NA	NA	NA	NA
WP_149115441.1\|1902989_1904150_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_149109575.1\|1904303_1904744_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_149109576.1\|1904740_1905415_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_149109577.1\|1905488_1906403_-	succinate--CoA ligase subunit alpha	NA	NA	NA	NA
WP_149109578.1\|1906473_1907319_-	hypothetical protein	NA	NA	NA	NA
WP_149109579.1\|1907414_1908614_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_149109580.1\|1908740_1909316_+	hypothetical protein	NA	NA	NA	NA
WP_149109581.1\|1909312_1910437_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
1909420:1909437	attL	NA	NA	NA	NA
WP_168218862.1\|1910531_1910678_+	hypothetical protein	NA	NA	NA	NA
WP_149109582.1\|1910745_1913001_+	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_149109583.1\|1913072_1914149_+	protein kinase	A0A1V0SBL0	Catovirus	3.0e-16	33.0
WP_149109584.1\|1914359_1915919_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149109585.1\|1915925_1916441_-\|protease	DJ-1/PfpI/YhbO family deglycase/protease	NA	NA	NA	NA
WP_149109586.1\|1916476_1918372_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_149109587.1\|1918390_1920298_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_149109588.1\|1920432_1921440_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_149109589.1\|1921543_1921849_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_149109590.1\|1921958_1923026_+	peptide chain release factor 1	NA	NA	NA	NA
WP_149109591.1\|1923127_1923559_+	OsmC family peroxiredoxin	NA	NA	NA	NA
WP_149109592.1\|1923734_1926806_+	PAS domain S-box protein	W8CYF6	Bacillus_phage	7.7e-25	28.7
WP_149109593.1\|1926915_1929177_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	5.1e-34	37.4
WP_149109594.1\|1929420_1931247_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149109595.1\|1931620_1932982_+	protein kinase	A0A2H4UVE2	Bodo_saltans_virus	5.1e-21	28.8
WP_149109596.1\|1933148_1933823_-	hypothetical protein	I1TQ57	Pseudomonas_phage	4.9e-25	34.4
WP_168218863.1\|1933840_1936003_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_149109598.1\|1936104_1937097_+	DUF1080 domain-containing protein	NA	NA	NA	NA
WP_168218864.1\|1937096_1938290_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_168218865.1\|1939075_1939375_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149109601.1\|1939428_1939740_-	hypothetical protein	NA	NA	NA	NA
WP_149109602.1\|1939830_1940922_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149109603.1\|1941060_1941648_-	hypothetical protein	NA	NA	NA	NA
WP_149109604.1\|1941726_1941972_-	hypothetical protein	NA	NA	NA	NA
WP_149109605.1\|1942028_1943108_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149109606.1\|1943115_1943331_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149109607.1\|1943359_1943584_-	hypothetical protein	NA	NA	NA	NA
WP_149109608.1\|1943692_1944460_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_168218808.1\|1944617_1945745_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149109609.1\|1945830_1946679_+	hypothetical protein	NA	NA	NA	NA
WP_149109610.1\|1946694_1946907_+	hypothetical protein	NA	NA	NA	NA
WP_149109611.1\|1947105_1947588_-\|tail	phage tail protein	NA	NA	NA	NA
WP_149109612.1\|1947764_1948448_+	hypothetical protein	NA	NA	NA	NA
WP_149109613.1\|1948599_1951110_-	DUF1080 domain-containing protein	A0A0M4JT11	Mollivirus	5.9e-15	27.8
WP_149109614.1\|1951415_1952048_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_149115442.1\|1952104_1952770_-	hypothetical protein	NA	NA	NA	NA
WP_149109615.1\|1952983_1953883_+	DUF5131 family protein	Q8W6R4	Burkholderia_virus	1.8e-83	51.4
WP_168218808.1\|1955380_1956509_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149109617.1\|1956613_1956940_+	hypothetical protein	NA	NA	NA	NA
WP_149109618.1\|1956933_1957392_+	hypothetical protein	NA	NA	NA	NA
WP_149109619.1\|1957388_1957673_+	hypothetical protein	NA	NA	NA	NA
WP_149109620.1\|1957669_1957966_+	hypothetical protein	NA	NA	NA	NA
WP_149109621.1\|1957969_1958353_-	response regulator	NA	NA	NA	NA
WP_149109622.1\|1958518_1958716_-	hypothetical protein	NA	NA	NA	NA
WP_149109623.1\|1958712_1959102_-	hypothetical protein	A0A2H5BPW3	Vibrio_phage	9.0e-40	57.9
WP_149109624.1\|1959098_1959668_-	DnaJ domain-containing protein	A0A1P8VV96	Erythrobacter_phage	3.3e-30	45.6
WP_149109625.1\|1959664_1959958_-	DUF2312 domain-containing protein	A0A0F6R615	Sinorhizobium_phage	2.3e-19	57.6
WP_149109626.1\|1959985_1960432_-	single-stranded DNA-binding protein	A0A0K1LLZ9	Caulobacter_phage	1.0e-39	51.5
1960182:1960199	attR	NA	NA	NA	NA
WP_149109627.1\|1960452_1961379_-	AAA family ATPase	A0A1W6JT44	Escherichia_phage	1.2e-53	42.5
WP_149109628.1\|1961389_1962634_-	AAA family ATPase	A0A1P8VVD9	Erythrobacter_phage	2.7e-53	35.1
WP_149115443.1\|1962659_1963685_-	hypothetical protein	A0A2I7RPX6	Vibrio_phage	3.1e-07	27.5
WP_149109629.1\|1964002_1964185_+	hypothetical protein	NA	NA	NA	NA
WP_149109630.1\|1964199_1964535_+	hypothetical protein	NA	NA	NA	NA
WP_149109631.1\|1964750_1965545_+	hypothetical protein	A0A088C4H0	Shewanella_sp._phage	6.2e-11	24.6

DBSCAN-SWA_6

1972822 : 2066668

uncultured_Mediterranean_phage(25.0%)

transposase,plate,tRNA,portal,integrase,tail,capsid

attL 1998635:1998694|attR 2053817:2055056

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149109641.1\|1972822_1974157_+\|portal	phage portal protein	NA	NA	NA	NA
WP_149109642.1\|1974160_1974937_+	hypothetical protein	NA	NA	NA	NA
WP_149109643.1\|1974953_1975400_+	hypothetical protein	NA	NA	NA	NA
WP_149109644.1\|1975405_1976896_+	hypothetical protein	E5EYS5	Acinetobacter_phage	3.5e-07	28.2
WP_149115445.1\|1976965_1977940_+	hypothetical protein	NA	NA	NA	NA
WP_149109645.1\|1978023_1978260_+	hypothetical protein	NA	NA	NA	NA
WP_149109646.1\|1978263_1978617_+	hypothetical protein	NA	NA	NA	NA
WP_149109647.1\|1978622_1979531_+	hypothetical protein	NA	NA	NA	NA
WP_149109648.1\|1979530_1979872_+	hypothetical protein	NA	NA	NA	NA
WP_149109649.1\|1979876_1980671_+	hypothetical protein	NA	NA	NA	NA
WP_168218867.1\|1980682_1980844_+	hypothetical protein	NA	NA	NA	NA
WP_149109650.1\|1980847_1982380_+\|tail	phage tail protein	B3GAJ6	uncultured_virus	3.2e-104	47.9
WP_149109651.1\|1982391_1982820_+	hypothetical protein	NA	NA	NA	NA
WP_149109652.1\|1982825_1983233_+	hypothetical protein	NA	NA	NA	NA
WP_149109653.1\|1983345_1983858_+	hypothetical protein	NA	NA	NA	NA
WP_149109654.1\|1983850_1985584_+	hypothetical protein	Q45YG8	Burkholderia_virus	5.0e-74	37.3
WP_149109655.1\|1985583_1986333_+	hypothetical protein	NA	NA	NA	NA
WP_149109656.1\|1986334_1986523_+	hypothetical protein	NA	NA	NA	NA
WP_149109657.1\|1986509_1987634_+	hypothetical protein	NA	NA	NA	NA
WP_149109658.1\|1987630_1988221_+\|plate	phage baseplate assembly protein V	B3GAJ7	uncultured_virus	3.2e-20	38.7
WP_149109659.1\|1988223_1988589_+\|tail	phage tail protein	NA	NA	NA	NA
WP_149109660.1\|1988600_1989722_+\|plate	baseplate protein	B3GAJ9	uncultured_virus	7.0e-61	43.1
WP_168219513.1\|1989767_1990388_+	hypothetical protein	NA	NA	NA	NA
WP_149109662.1\|1990403_1992014_+	hypothetical protein	A0A0H4IR29	Brucella_phage	6.0e-13	34.4
WP_149109663.1\|1992079_1992397_+	hypothetical protein	NA	NA	NA	NA
WP_149109664.1\|1992393_1992816_+	response regulator	NA	NA	NA	NA
WP_149109665.1\|1992826_1993351_+	hypothetical protein	NA	NA	NA	NA
WP_149109666.1\|1993350_1994142_+	hypothetical protein	A0A1B1IR63	uncultured_Mediterranean_phage	3.4e-09	41.7
WP_149109667.1\|1994156_1996094_+	hypothetical protein	A0A1B1IWK1	uncultured_Mediterranean_phage	9.5e-05	34.3
WP_168218868.1\|1996209_1998108_+	LamG domain-containing protein	A0A076YL80	Mesorhizobium_phage	2.5e-50	36.9
WP_149109669.1\|1998111_1998510_+	M15 family metallopeptidase	A0A0H3V0Q8	Geobacillus_virus	4.3e-21	40.3
WP_168218869.1\|1998519_1998657_+	hypothetical protein	NA	NA	NA	NA
1998635:1998694	attL	NA	NA	NA	NA
WP_168218808.1\|1998701_1999829_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_168218870.1\|1999859_2000003_+	hypothetical protein	NA	NA	NA	NA
WP_149109670.1\|2000006_2000345_+	hypothetical protein	NA	NA	NA	NA
WP_149109671.1\|2000328_2000508_+	hypothetical protein	NA	NA	NA	NA
WP_149109672.1\|2000771_2001008_+	hypothetical protein	NA	NA	NA	NA
WP_149115446.1\|2001089_2002247_+\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	3.0e-83	53.7
WP_149109673.1\|2002243_2002423_+	adhesin	NA	NA	NA	NA
WP_149109674.1\|2002723_2007862_+	hypothetical protein	I3PUW5	Vibrio_phage	1.5e-270	36.9
WP_149109675.1\|2008160_2008550_+	hypothetical protein	NA	NA	NA	NA
WP_149109676.1\|2008777_2008990_-	hypothetical protein	NA	NA	NA	NA
WP_149109677.1\|2009335_2009989_-	SOS response-associated peptidase	NA	NA	NA	NA
WP_149109678.1\|2010003_2010447_-	hypothetical protein	NA	NA	NA	NA
WP_149109679.1\|2010589_2011813_+	nucleotidyltransferase	A0A1W6JNT0	Morganella_phage	8.5e-36	29.4
WP_149109680.1\|2011822_2012128_+	hypothetical protein	NA	NA	NA	NA
WP_149109681.1\|2012137_2012599_+	hypothetical protein	NA	NA	NA	NA
WP_149109682.1\|2012600_2012804_-	hypothetical protein	NA	NA	NA	NA
WP_149109683.1\|2013035_2013287_+	hypothetical protein	NA	NA	NA	NA
WP_149109684.1\|2013309_2014104_-	exodeoxyribonuclease III	NA	NA	NA	NA
WP_149109685.1\|2014335_2019498_+	DEAD/DEAH box helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	2.0e-57	22.8
WP_149109686.1\|2019494_2022305_+	DEAD/DEAH box helicase family protein	A0A1B1IUI1	uncultured_Mediterranean_phage	1.5e-38	27.5
WP_149109687.1\|2022310_2027119_+	N-6 DNA methylase	A0A1B1IUC6	uncultured_Mediterranean_phage	3.1e-41	22.9
WP_149109688.1\|2027147_2028263_-	hypothetical protein	NA	NA	NA	NA
WP_149109689.1\|2028616_2030125_+	protein kinase	Q8QNG7	Ectocarpus_siliculosus_virus	1.4e-11	34.9
WP_149109690.1\|2030145_2031012_-	hypothetical protein	NA	NA	NA	NA
WP_149109691.1\|2031377_2032403_+	hypothetical protein	NA	NA	NA	NA
WP_149109692.1\|2032399_2033224_+	hypothetical protein	NA	NA	NA	NA
WP_149109693.1\|2033328_2033706_-	hypothetical protein	NA	NA	NA	NA
WP_149109694.1\|2034223_2035096_+	hypothetical protein	NA	NA	NA	NA
WP_149109695.1\|2035297_2035687_-	hypothetical protein	NA	NA	NA	NA
WP_149109696.1\|2035736_2036117_-	hypothetical protein	NA	NA	NA	NA
WP_149109697.1\|2036271_2038020_+	hypothetical protein	NA	NA	NA	NA
WP_149109699.1\|2038722_2039403_-	hypothetical protein	NA	NA	NA	NA
WP_149109700.1\|2039511_2040093_-\|portal	phage portal protein	NA	NA	NA	NA
WP_149109701.1\|2040059_2040323_-	hypothetical protein	NA	NA	NA	NA
WP_149109702.1\|2040620_2043992_-	hypothetical protein	NA	NA	NA	NA
WP_149109703.1\|2044331_2044595_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_149109704.1\|2044672_2044981_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_149109706.1\|2045449_2045842_+	PIN domain-containing protein	NA	NA	NA	NA
WP_149109707.1\|2045914_2047375_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_149109708.1\|2047384_2047579_+	hypothetical protein	NA	NA	NA	NA
WP_149109709.1\|2047736_2047979_+	hypothetical protein	NA	NA	NA	NA
WP_149109710.1\|2048197_2049436_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149109711.1\|2049551_2050496_-	hypothetical protein	NA	NA	NA	NA
WP_149109712.1\|2050745_2051108_-	hypothetical protein	NA	NA	NA	NA
WP_168218871.1\|2051200_2053795_-	hypothetical protein	NA	NA	NA	NA
WP_168218808.1\|2053883_2055011_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149109714.1\|2055520_2056201_+	AAA family ATPase	A0A2H4JGZ2	uncultured_Caudovirales_phage	9.6e-13	29.4
2053817:2055056	attR	NA	NA	NA	NA
WP_149109715.1\|2056210_2056513_+	hypothetical protein	NA	NA	NA	NA
WP_149109716.1\|2056509_2057424_+	plasmid encoded RepA protein	NA	NA	NA	NA
WP_149109717.1\|2058586_2059435_-	SLATT domain-containing protein	NA	NA	NA	NA
WP_149109718.1\|2059511_2062553_-	hypothetical protein	NA	NA	NA	NA
WP_149109719.1\|2062803_2063352_-\|transposase	transposase	NA	NA	NA	NA
WP_149109720.1\|2063285_2063783_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149109721.1\|2064296_2065325_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149109722.1\|2065566_2065929_-	hypothetical protein	NA	NA	NA	NA
WP_149109723.1\|2066029_2066668_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

2366611 : 2412801

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168218808.1\|2366611_2367739_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_168218895.1\|2368209_2370927_+	PAS domain-containing protein	A0A1V0SGX0	Hokovirus	3.7e-07	24.3
WP_168218896.1\|2371109_2371502_+\|transposase	transposase	NA	NA	NA	NA
WP_149109941.1\|2371473_2372070_+\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	9.3e-12	28.1
WP_149115459.1\|2372063_2373155_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_149109942.1\|2373358_2377534_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149109943.1\|2377724_2378054_+	hypothetical protein	NA	NA	NA	NA
WP_149109944.1\|2378126_2378546_+	SnoaL-like domain-containing protein	NA	NA	NA	NA
WP_168218897.1\|2378879_2381165_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	3.3e-25	32.1
WP_168218898.1\|2381183_2382392_-	protein kinase	A0A140IPJ0	Avian_leukosis_and_sarcoma_virus	9.7e-16	30.9
WP_149109947.1\|2382741_2384292_-	hypothetical protein	NA	NA	NA	NA
WP_149109948.1\|2384319_2385264_-	AAA domain-containing protein	NA	NA	NA	NA
WP_149109949.1\|2385297_2387637_-	transglutaminase domain-containing protein	NA	NA	NA	NA
WP_149109950.1\|2387626_2388895_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_149109951.1\|2388921_2389752_-	hypothetical protein	NA	NA	NA	NA
WP_149109952.1\|2391192_2392593_-	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_149109953.1\|2392616_2393708_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_168218899.1\|2394781_2395174_-	response regulator	NA	NA	NA	NA
WP_149109955.1\|2395364_2396219_-	ThuA domain-containing protein	NA	NA	NA	NA
WP_149109956.1\|2396378_2399489_+	c-type cytochrome	NA	NA	NA	NA
WP_149109957.1\|2399627_2400008_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_149109958.1\|2400111_2400873_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_149109959.1\|2401765_2402894_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.7e-19	26.2
WP_168218900.1\|2403381_2409174_+	hypothetical protein	NA	NA	NA	NA
WP_149109961.1\|2409631_2410090_-	DUF4279 domain-containing protein	NA	NA	NA	NA
WP_149109962.1\|2410180_2411113_-\|transposase	transposase	NA	NA	NA	NA
WP_168218901.1\|2411217_2412801_+\|transposase	IS21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2800693 : 2846460

Acanthamoeba_polyphaga_mimivirus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149109168.1\|2800693_2801227_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_168218823.1\|2801124_2801730_+\|transposase	transposase	NA	NA	NA	NA
WP_149110270.1\|2802247_2802985_-	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_149110271.1\|2803060_2803510_-	SnoaL-like domain-containing protein	NA	NA	NA	NA
WP_149110272.1\|2803639_2804176_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y3R2	Acanthamoeba_polyphaga_mimivirus	4.2e-19	55.3
WP_149110274.1\|2806998_2807607_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149110275.1\|2807864_2808782_+	diguanylate cyclase	NA	NA	NA	NA
WP_168218927.1\|2809288_2809543_+	hypothetical protein	NA	NA	NA	NA
WP_149110277.1\|2809606_2809984_+	hypothetical protein	NA	NA	NA	NA
WP_149110278.1\|2810001_2812578_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_149110279.1\|2813214_2814609_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149110280.1\|2814681_2815824_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149110281.1\|2815810_2816014_+	hypothetical protein	NA	NA	NA	NA
WP_149110282.1\|2817125_2817638_-	hypothetical protein	NA	NA	NA	NA
WP_149110283.1\|2817550_2817793_-	hypothetical protein	NA	NA	NA	NA
WP_149110284.1\|2818272_2819988_+	hypothetical protein	NA	NA	NA	NA
WP_149110285.1\|2820211_2822068_-	SAP domain-containing protein	NA	NA	NA	NA
WP_168218928.1\|2822245_2822602_+	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_149110287.1\|2822698_2822989_-	hypothetical protein	NA	NA	NA	NA
WP_149115478.1\|2823428_2824391_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_149110288.1\|2824542_2824890_-	hypothetical protein	NA	NA	NA	NA
WP_149110289.1\|2824894_2825119_+	hypothetical protein	NA	NA	NA	NA
WP_168218929.1\|2825140_2825299_+	hypothetical protein	NA	NA	NA	NA
WP_149110290.1\|2825435_2826050_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_149110291.1\|2826109_2826406_-	hypothetical protein	NA	NA	NA	NA
WP_168218930.1\|2826528_2827017_-	DUF2314 domain-containing protein	NA	NA	NA	NA
WP_168218931.1\|2827477_2828743_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149115479.1\|2831463_2831730_+	hypothetical protein	NA	NA	NA	NA
WP_149110294.1\|2831810_2833115_+	hypothetical protein	NA	NA	NA	NA
WP_168218932.1\|2833263_2833425_+	hypothetical protein	NA	NA	NA	NA
WP_149110295.1\|2833814_2834375_-	hypothetical protein	NA	NA	NA	NA
WP_149110296.1\|2834614_2834938_-	hypothetical protein	NA	NA	NA	NA
WP_149115480.1\|2836553_2836850_+	hypothetical protein	NA	NA	NA	NA
WP_149110297.1\|2836934_2837276_+	hypothetical protein	NA	NA	NA	NA
WP_149110298.1\|2837479_2837815_+	hypothetical protein	NA	NA	NA	NA
WP_149110299.1\|2837890_2838343_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_149110300.1\|2838453_2839011_+	hypothetical protein	NA	NA	NA	NA
WP_149110301.1\|2839359_2839605_+	hypothetical protein	NA	NA	NA	NA
WP_168218933.1\|2839911_2841753_-	AAA family ATPase	NA	NA	NA	NA
WP_149110303.1\|2842524_2842863_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_168218808.1\|2842942_2844070_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149110304.1\|2844208_2844520_+	plasmid stabilization protein	NA	NA	NA	NA
WP_149110305.1\|2844667_2845021_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168218934.1\|2845737_2846460_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

3757808 : 3886172

Acanthocystis_turfacea_Chlorella_virus(13.33%)

integrase,transposase

attL 3797243:3797260|attR 3849218:3849235

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149109941.1\|3757808_3758405_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	9.3e-12	28.1
WP_168218896.1\|3758376_3758769_-\|transposase	transposase	NA	NA	NA	NA
WP_149111005.1\|3758981_3759944_+	DUF4013 domain-containing protein	NA	NA	NA	NA
WP_149111006.1\|3760204_3760804_-	hypothetical protein	NA	NA	NA	NA
WP_168219017.1\|3760917_3761061_-	hypothetical protein	NA	NA	NA	NA
WP_168219018.1\|3761087_3765347_-	protein kinase	A0A2H4UVE2	Bodo_saltans_virus	2.5e-18	28.4
WP_168219019.1\|3765445_3766051_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149111009.1\|3766185_3766665_+	hypothetical protein	NA	NA	NA	NA
WP_149111010.1\|3766847_3771698_+	hypothetical protein	NA	NA	NA	NA
WP_168219020.1\|3772146_3773439_+	TolC family protein	NA	NA	NA	NA
WP_149115512.1\|3773867_3774071_-	hypothetical protein	NA	NA	NA	NA
WP_149111012.1\|3775703_3778676_-	hypothetical protein	NA	NA	NA	NA
WP_149111013.1\|3778748_3779501_-	hypothetical protein	NA	NA	NA	NA
WP_149111014.1\|3779564_3782045_-	protein kinase	M1IB97	Acanthocystis_turfacea_Chlorella_virus	1.4e-13	29.8
WP_149111015.1\|3782156_3782720_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149111016.1\|3783013_3783769_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	1.3e-37	36.9
WP_149111017.1\|3783897_3785277_-	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_168219021.1\|3785304_3786285_-	DUF3500 domain-containing protein	NA	NA	NA	NA
WP_149111019.1\|3786487_3789244_-	protein kinase	S4VV57	Pandoravirus	4.6e-13	30.0
WP_149111020.1\|3789240_3789978_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149111021.1\|3790010_3790487_+	hypothetical protein	NA	NA	NA	NA
WP_168219022.1\|3790658_3791741_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149111022.1\|3791906_3793622_+	hypothetical protein	NA	NA	NA	NA
WP_149111023.1\|3793687_3794491_-	ion transporter	NA	NA	NA	NA
WP_149111024.1\|3794950_3795148_+	hypothetical protein	NA	NA	NA	NA
WP_149111025.1\|3795144_3795903_+	hypothetical protein	NA	NA	NA	NA
WP_149111026.1\|3795938_3796544_+	30S ribosomal protein S4	NA	NA	NA	NA
WP_149111027.1\|3796577_3797024_+	hypothetical protein	NA	NA	NA	NA
WP_149111028.1\|3797166_3798495_+	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
3797243:3797260	attL	NA	NA	NA	NA
WP_149111029.1\|3798510_3799521_-	hypothetical protein	NA	NA	NA	NA
WP_149111030.1\|3799574_3801287_-	hypothetical protein	NA	NA	NA	NA
WP_149111031.1\|3801401_3804353_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	7.0e-84	35.4
WP_149111032.1\|3804517_3807229_+	hypothetical protein	NA	NA	NA	NA
WP_149111033.1\|3807364_3809668_+	oligopeptide transporter, OPT family	NA	NA	NA	NA
WP_149111034.1\|3809711_3810440_-	NTP transferase domain-containing protein	H9NC64	Sphingomonas_phage	9.2e-46	42.8
WP_149111035.1\|3810495_3811509_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	7.2e-73	44.8
WP_149115514.1\|3812519_3813902_+	transcription termination factor Rho	NA	NA	NA	NA
WP_149115515.1\|3814452_3814710_+	hypothetical protein	NA	NA	NA	NA
WP_149111036.1\|3814785_3815835_+	mannose-6-phosphate isomerase	NA	NA	NA	NA
WP_149111037.1\|3815789_3816497_+	5-oxoprolinase subunit PxpA	NA	NA	NA	NA
WP_149111038.1\|3816841_3817579_+	hypothetical protein	NA	NA	NA	NA
WP_149111039.1\|3817686_3818439_+	PIG-L family deacetylase	NA	NA	NA	NA
WP_149111040.1\|3819072_3822201_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_149111041.1\|3822662_3823421_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_168219023.1\|3823872_3829197_+	hypothetical protein	NA	NA	NA	NA
WP_149111043.1\|3829468_3832735_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_168219024.1\|3834011_3842624_-	tandem-95 repeat protein	NA	NA	NA	NA
WP_149111045.1\|3843697_3844627_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_149111046.1\|3844671_3845301_+	hypothetical protein	NA	NA	NA	NA
WP_149111047.1\|3845419_3846766_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168219025.1\|3847861_3848674_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0P0I4A4	Acinetobacter_phage	4.8e-11	36.0
WP_149111048.1\|3848655_3849306_-\|transposase	IS3 family transposase	NA	NA	NA	NA
3849218:3849235	attR	NA	NA	NA	NA
WP_149111049.1\|3849348_3849672_-	hypothetical protein	NA	NA	NA	NA
WP_149111050.1\|3849665_3850094_-\|transposase	transposase	NA	NA	NA	NA
WP_149109721.1\|3850505_3851534_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149111051.1\|3851665_3852826_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_168219026.1\|3852822_3852981_+	hypothetical protein	NA	NA	NA	NA
WP_149109721.1\|3853072_3854101_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168219027.1\|3855631_3859249_-	c-type cytochrome	NA	NA	NA	NA
WP_149111053.1\|3859373_3859532_-	hypothetical protein	NA	NA	NA	NA
WP_149111054.1\|3859584_3862419_-	DUF2341 domain-containing protein	NA	NA	NA	NA
WP_149111055.1\|3862633_3862873_-	hypothetical protein	NA	NA	NA	NA
WP_168219028.1\|3864176_3864953_+	hypothetical protein	NA	NA	NA	NA
WP_149111057.1\|3865682_3866786_-\|transposase	transposase	A0A0P0ZEB3	Stx2-converting_phage	2.1e-25	31.5
WP_149111058.1\|3866808_3867012_-\|transposase	transposase	A0A0P0ZDM8	Stx2-converting_phage	6.4e-05	56.5
WP_168219029.1\|3867072_3867435_+	hypothetical protein	NA	NA	NA	NA
WP_149111059.1\|3868293_3868683_+	protein kinase	NA	NA	NA	NA
WP_149111060.1\|3868722_3869580_+	protein kinase	M1HV07	Acanthocystis_turfacea_Chlorella_virus	1.0e-11	42.7
WP_149111061.1\|3870177_3871074_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_149111062.1\|3871104_3871941_+	hypothetical protein	NA	NA	NA	NA
WP_149111063.1\|3872197_3873772_+	ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	1.8e-25	25.3
WP_149111064.1\|3873854_3874631_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_149111065.1\|3874688_3875117_-	cupin domain-containing protein	NA	NA	NA	NA
WP_149111066.1\|3875295_3875913_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149111067.1\|3875929_3878773_+	protein kinase	A0A285PX80	Cedratvirus	1.3e-15	36.7
WP_149111068.1\|3878899_3879079_+	hypothetical protein	NA	NA	NA	NA
WP_149111069.1\|3879250_3881026_-	hypothetical protein	NA	NA	NA	NA
WP_149115412.1\|3881088_3881334_-	hypothetical protein	NA	NA	NA	NA
WP_149108794.1\|3881899_3883024_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_168219030.1\|3882962_3884897_-	hypothetical protein	NA	NA	NA	NA
WP_149109223.1\|3884895_3885675_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.2e-29	34.9
WP_149111070.1\|3885828_3886038_+	hypothetical protein	NA	NA	NA	NA
WP_149111071.1\|3886031_3886172_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_10

3946037 : 4040993

Leptospira_phage(12.5%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149111119.1\|3946037_3946721_+\|transposase	transposase	NA	NA	NA	NA
WP_168219036.1\|3946841_3947282_+	GatB/YqeY domain-containing protein	NA	NA	NA	NA
WP_149111121.1\|3947457_3948534_+	nitronate monooxygenase	NA	NA	NA	NA
WP_149111122.1\|3948522_3948741_-	2-hydroxymuconate tautomerase family protein	NA	NA	NA	NA
WP_149111123.1\|3948768_3949482_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_149111124.1\|3949545_3949965_-	Ohr family peroxiredoxin	NA	NA	NA	NA
WP_149111125.1\|3950200_3950707_-	hypothetical protein	NA	NA	NA	NA
WP_149111126.1\|3950805_3951237_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149111127.1\|3951292_3952639_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_149111128.1\|3952631_3955856_-	MMPL family transporter	S5VTK5	Leptospira_phage	2.1e-49	21.7
WP_149111129.1\|3955923_3957417_-	TolC family protein	NA	NA	NA	NA
WP_149111130.1\|3958055_3958325_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_149111131.1\|3958444_3960718_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_149111132.1\|3960781_3961336_+	hypothetical protein	NA	NA	NA	NA
WP_149111133.1\|3961341_3961800_+	hypothetical protein	NA	NA	NA	NA
WP_149111134.1\|3961979_3965411_-	protein kinase	S4VV57	Pandoravirus	1.1e-16	32.8
WP_149111135.1\|3965385_3966003_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149111136.1\|3966207_3967581_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_149111137.1\|3967704_3968298_+	mismatch-specific DNA-glycosylase	NA	NA	NA	NA
WP_168219037.1\|3968540_3969839_+	HlyD family secretion protein	NA	NA	NA	NA
WP_168219038.1\|3969835_3971401_+	MFS transporter	NA	NA	NA	NA
WP_149111140.1\|3971415_3972915_-	TolC family protein	NA	NA	NA	NA
WP_168219039.1\|3973082_3973847_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	4.4e-14	24.2
WP_149111142.1\|3974326_3975151_-	sialate O-acetylesterase	NA	NA	NA	NA
WP_149111143.1\|3975166_3977029_-	rhamnogalacturonan acetylesterase	NA	NA	NA	NA
WP_168219040.1\|3981434_3981581_-	hypothetical protein	NA	NA	NA	NA
WP_149111145.1\|3981940_3982396_-	hypothetical protein	NA	NA	NA	NA
WP_149111146.1\|3982484_3982808_-	hypothetical protein	NA	NA	NA	NA
WP_149115520.1\|3982932_3983202_-	hypothetical protein	NA	NA	NA	NA
WP_168219041.1\|3983703_3983853_-	hypothetical protein	NA	NA	NA	NA
WP_149111147.1\|3983831_3984290_-	hypothetical protein	NA	NA	NA	NA
WP_149111148.1\|3984316_3984682_-	hypothetical protein	NA	NA	NA	NA
WP_149111149.1\|3984705_3989106_-	protein kinase	A0A1B1IUU3	uncultured_Mediterranean_phage	3.7e-12	26.2
WP_149111150.1\|3989118_3989733_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149111151.1\|3990288_3990495_-	hypothetical protein	NA	NA	NA	NA
WP_149111152.1\|3990823_3991366_-	glyoxalase	NA	NA	NA	NA
WP_149111153.1\|3991490_3992558_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_149115521.1\|3992602_3992998_-	tryptophan-rich sensory protein	NA	NA	NA	NA
WP_149111154.1\|3993040_3993697_-	DUF1990 family protein	NA	NA	NA	NA
WP_149111155.1\|3993746_3994670_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_149111156.1\|3994740_3995448_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_149111157.1\|3996445_3996685_+	hypothetical protein	NA	NA	NA	NA
WP_149111158.1\|3996673_3997453_-	hypothetical protein	NA	NA	NA	NA
WP_168219042.1\|3997691_3997850_-	hypothetical protein	NA	NA	NA	NA
WP_149111159.1\|3997986_3998766_-	AAA family ATPase	NA	NA	NA	NA
WP_149111160.1\|3999315_4000233_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149109721.1\|4000474_4001503_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149111051.1\|4001634_4002795_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_168219026.1\|4002791_4002950_+	hypothetical protein	NA	NA	NA	NA
WP_149109721.1\|4003041_4004070_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149111161.1\|4004516_4005668_-	DNA modification methylase	Q708N6	Streptococcus_phage	5.2e-75	38.7
WP_149111162.1\|4006572_4007724_+\|transposase	transposase	NA	NA	NA	NA
WP_149109166.1\|4007847_4009080_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_149111163.1\|4009515_4010052_+	hypothetical protein	NA	NA	NA	NA
WP_149115522.1\|4010305_4011622_+	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_149111164.1\|4011636_4012221_+	hypothetical protein	NA	NA	NA	NA
WP_149111165.1\|4012207_4012534_+	hypothetical protein	NA	NA	NA	NA
WP_149111166.1\|4012593_4013937_+	cytochrome P450	A0A2K9L069	Tupanvirus	1.0e-21	27.1
WP_149111167.1\|4014239_4015769_-	hypothetical protein	NA	NA	NA	NA
WP_149111168.1\|4016014_4018786_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_168219043.1\|4020011_4020173_-	hypothetical protein	NA	NA	NA	NA
WP_149111169.1\|4020317_4020581_-	hypothetical protein	NA	NA	NA	NA
WP_149111170.1\|4021646_4022582_-\|transposase	transposase	NA	NA	NA	NA
WP_149111171.1\|4023467_4023656_-	hypothetical protein	NA	NA	NA	NA
WP_149111172.1\|4023688_4024033_+	hypothetical protein	NA	NA	NA	NA
WP_149111173.1\|4024260_4025025_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_149111174.1\|4025425_4026244_-	hypothetical protein	NA	NA	NA	NA
WP_149111175.1\|4026627_4026918_+	hypothetical protein	NA	NA	NA	NA
WP_149115523.1\|4026987_4027614_-	GDSL family lipase	NA	NA	NA	NA
WP_149111176.1\|4028012_4028537_+	YceK/YidQ family lipoprotein	NA	NA	NA	NA
WP_149111177.1\|4028609_4029422_-	hypothetical protein	NA	NA	NA	NA
WP_149111178.1\|4029793_4030069_-	hypothetical protein	NA	NA	NA	NA
WP_149111179.1\|4030388_4030793_-	hypothetical protein	A0A172Q0R3	Acinetobacter_phage	8.0e-15	37.4
WP_149111180.1\|4030804_4032754_-	hypothetical protein	A0A1W6DY32	Aeromonas_phage	3.3e-159	46.7
WP_149111181.1\|4033322_4033658_-	hypothetical protein	NA	NA	NA	NA
WP_149111182.1\|4033894_4034467_-	hypothetical protein	NA	NA	NA	NA
WP_168219044.1\|4035495_4035918_-\|transposase	transposase	NA	NA	NA	NA
WP_168219045.1\|4035914_4036418_-\|transposase	transposase	NA	NA	NA	NA
WP_168218823.1\|4036526_4037132_-\|transposase	transposase	NA	NA	NA	NA
WP_149111185.1\|4037029_4037563_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_168219046.1\|4037588_4037966_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168219047.1\|4038112_4038496_-	hypothetical protein	NA	NA	NA	NA
WP_149111187.1\|4038535_4038787_+	hypothetical protein	NA	NA	NA	NA
WP_149111189.1\|4040003_4040993_+\|transposase	IS1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

4374343 : 4397336

Methylophilaceae_phage(50.0%)

integrase,transposase

attL 4396290:4396305|attR 4399244:4399259

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149110579.1\|4374343_4375720_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149110580.1\|4375848_4376457_+	hypothetical protein	NA	NA	NA	NA
WP_149109166.1\|4376548_4377781_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_149111447.1\|4378050_4378269_-	hypothetical protein	NA	NA	NA	NA
WP_149111448.1\|4378479_4378959_-	hypothetical protein	NA	NA	NA	NA
WP_149111449.1\|4379005_4379296_-	hypothetical protein	NA	NA	NA	NA
WP_149111450.1\|4379481_4379907_+	hypothetical protein	NA	NA	NA	NA
WP_149111451.1\|4380120_4380651_+	YceK/YidQ family lipoprotein	NA	NA	NA	NA
WP_149111452.1\|4380943_4381612_-	hypothetical protein	NA	NA	NA	NA
WP_149111453.1\|4382140_4382479_-	hypothetical protein	NA	NA	NA	NA
WP_149111387.1\|4382972_4383215_-	hypothetical protein	NA	NA	NA	NA
WP_149111388.1\|4383788_4385165_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149111454.1\|4385217_4385598_-	DUF1376 domain-containing protein	A0A2H4FS76	Methylophilaceae_phage	2.9e-11	35.5
WP_149111455.1\|4385732_4386194_-	hypothetical protein	NA	NA	NA	NA
WP_149111456.1\|4386190_4386541_-	DUF1064 domain-containing protein	A0A0U2C0S3	Paracoccus_phage	6.0e-11	40.6
WP_149111457.1\|4386530_4386791_-	hypothetical protein	NA	NA	NA	NA
WP_149111458.1\|4387063_4387411_+	hypothetical protein	NA	NA	NA	NA
WP_149111459.1\|4387598_4388102_+	hypothetical protein	NA	NA	NA	NA
WP_149111460.1\|4388101_4388452_+	phage recombination protein Bet	NA	NA	NA	NA
WP_149111461.1\|4388515_4388968_+	hypothetical protein	NA	NA	NA	NA
WP_149111462.1\|4388969_4389713_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_168219079.1\|4389711_4390941_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_149111464.1\|4391084_4391840_+	hypothetical protein	NA	NA	NA	NA
WP_149111465.1\|4391823_4392225_+	hypothetical protein	NA	NA	NA	NA
WP_149111466.1\|4392275_4392725_+	hypothetical protein	NA	NA	NA	NA
WP_149111467.1\|4392752_4393085_-	hypothetical protein	NA	NA	NA	NA
WP_149111468.1\|4393357_4394767_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149111469.1\|4395472_4396036_+	hypothetical protein	NA	NA	NA	NA
WP_149111470.1\|4396204_4396630_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
4396290:4396305	attL	NA	NA	NA	NA
WP_149111471.1\|4396655_4397336_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_149111471.1\|4396655_4397336_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
4399244:4399259	attR	NA	NA	NA	NA

DBSCAN-SWA_12

4438399 : 4494672

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149115538.1\|4438399_4438723_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_168219085.1\|4438741_4439611_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	4.9e-54	40.8
WP_149111500.1\|4439607_4440789_-\|transposase	ISAs1 family transposase	Q716C1	Shigella_phage	1.4e-06	33.0
WP_149111501.1\|4440905_4442102_+	redoxin domain-containing protein	NA	NA	NA	NA
WP_149115539.1\|4442428_4442956_+	hypothetical protein	NA	NA	NA	NA
WP_149111502.1\|4443482_4444769_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_149111503.1\|4444842_4445649_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_168219521.1\|4447941_4449156_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_149111505.1\|4449152_4449593_+	response regulator	NA	NA	NA	NA
WP_168219086.1\|4449598_4453468_+	PAS domain S-box protein	NA	NA	NA	NA
WP_149111507.1\|4453566_4454601_-	diguanylate cyclase	NA	NA	NA	NA
WP_149111508.1\|4454617_4456096_-	AAA family ATPase	A0A2I6UHH1	Bacillus_phage	2.5e-05	27.6
WP_149111509.1\|4456092_4456533_-	hypothetical protein	NA	NA	NA	NA
WP_149111510.1\|4457146_4466263_+	hypothetical protein	NA	NA	NA	NA
WP_168219087.1\|4467265_4469263_+	AAA family ATPase	NA	NA	NA	NA
WP_149111512.1\|4469351_4471322_+	acyltransferase family protein	NA	NA	NA	NA
WP_168219088.1\|4471322_4472474_-	response regulator	NA	NA	NA	NA
WP_149111514.1\|4472513_4474397_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	2.0e-12	30.4
WP_149111515.1\|4474477_4475296_-	sigma-70 family RNA polymerase sigma factor	G8CLC7	Synechococcus_phage	7.0e-26	30.8
WP_149111516.1\|4475332_4476319_-	response regulator	W8CYM9	Bacillus_phage	1.5e-19	38.1
WP_149115540.1\|4476315_4477137_-	response regulator	NA	NA	NA	NA
WP_149111517.1\|4477018_4477468_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_149111518.1\|4479213_4481106_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_149111519.1\|4481297_4489370_+	hypothetical protein	A0A1W6JQC9	Corynebacterium_phage	4.4e-11	47.2
WP_149111520.1\|4489710_4489968_-	hypothetical protein	NA	NA	NA	NA
WP_149111521.1\|4490088_4491399_-	hypothetical protein	NA	NA	NA	NA
WP_149111522.1\|4491479_4492514_+	hypothetical protein	NA	NA	NA	NA
WP_149111523.1\|4493509_4493806_+\|transposase	transposase	Q716C1	Shigella_phage	3.4e-07	34.1
WP_168219089.1\|4493802_4494672_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.1e-51	39.7

DBSCAN-SWA_13

5108251 : 5165429

Bacillus_phage(18.18%)

integrase,tRNA,transposase

attL 5151334:5151348|attR 5166151:5166165

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149111986.1\|5108251_5109277_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_149111987.1\|5109334_5109889_-	hypothetical protein	NA	NA	NA	NA
WP_149111988.1\|5109926_5110841_-	biotin-dependent carboxyltransferase family protein	NA	NA	NA	NA
WP_149115578.1\|5110850_5112122_-	sodium:proton antiporter	NA	NA	NA	NA
WP_149115579.1\|5112273_5112795_+	ParB N-terminal domain-containing protein	A0A1B1P7B5	Bacillus_phage	1.1e-19	45.2
WP_149111989.1\|5112795_5113788_-	NAD-dependent epimerase/dehydratase family protein	M4QPK0	Synechococcus_phage	5.0e-10	31.2
WP_149111990.1\|5113784_5114957_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_149111991.1\|5115027_5116353_-	hypothetical protein	NA	NA	NA	NA
WP_149111992.1\|5116554_5117439_+	FkbM family methyltransferase	NA	NA	NA	NA
WP_149111993.1\|5117440_5118742_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_149115580.1\|5119060_5119546_-	endonuclease	A0A0E3M1E6	Bacillus_phage	2.8e-14	35.8
WP_149111994.1\|5119590_5120022_-	hypothetical protein	NA	NA	NA	NA
WP_149111995.1\|5120168_5121392_+	nucleotidyltransferase	A0A1W6JNT0	Morganella_phage	1.6e-34	33.9
WP_149111996.1\|5121393_5121852_+	hypothetical protein	NA	NA	NA	NA
WP_168219121.1\|5121875_5125412_-	DEAD/DEAH box helicase	E3T5F3	Cafeteria_roenbergensis_virus	5.4e-06	24.7
WP_149111998.1\|5126718_5126934_-	hypothetical protein	NA	NA	NA	NA
WP_149111999.1\|5127255_5127924_-	hypothetical protein	NA	NA	NA	NA
WP_149112000.1\|5128367_5128958_+\|transposase	transposase	NA	NA	NA	NA
WP_149112002.1\|5129308_5130520_-	hypothetical protein	A0A1S6KZY3	Salmonella_phage	3.8e-20	42.1
WP_168219122.1\|5130747_5133519_+	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	2.3e-20	22.9
WP_149112004.1\|5133540_5136591_+	site-specific DNA-methyltransferase	G8I4P9	Mycobacterium_phage	1.1e-26	26.4
WP_149112005.1\|5136587_5139758_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_168219123.1\|5140002_5140677_+	hypothetical protein	NA	NA	NA	NA
WP_168219124.1\|5140684_5141461_+	hypothetical protein	NA	NA	NA	NA
WP_149112008.1\|5142901_5143666_+	hypothetical protein	NA	NA	NA	NA
WP_149112009.1\|5143729_5144173_-	hypothetical protein	NA	NA	NA	NA
WP_149112010.1\|5146055_5146394_-	hypothetical protein	NA	NA	NA	NA
WP_149112011.1\|5146643_5147639_+	AAA domain-containing protein	H6WG28	Cyanophage	8.4e-58	38.6
WP_149112012.1\|5147682_5148534_+	hypothetical protein	NA	NA	NA	NA
WP_149112013.1\|5148579_5149824_+	hypothetical protein	G3MAV6	Bacillus_virus	9.6e-35	30.6
WP_149112014.1\|5150112_5151489_+	hypothetical protein	NA	NA	NA	NA
5151334:5151348	attL	NA	NA	NA	NA
WP_149112015.1\|5151500_5152004_+	hypothetical protein	NA	NA	NA	NA
WP_149112016.1\|5152131_5152722_+	hypothetical protein	NA	NA	NA	NA
WP_149112017.1\|5152951_5153623_+	hypothetical protein	NA	NA	NA	NA
WP_149112018.1\|5153594_5154842_+	hypothetical protein	NA	NA	NA	NA
WP_149112019.1\|5154834_5155419_+	hypothetical protein	NA	NA	NA	NA
WP_168219125.1\|5155931_5158784_+	hypothetical protein	NA	NA	NA	NA
WP_149112021.1\|5159331_5160126_-	hypothetical protein	NA	NA	NA	NA
WP_149112022.1\|5160380_5160674_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149112023.1\|5160588_5161215_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_149112024.1\|5161211_5161508_-\|transposase	transposase	Q716C1	Shigella_phage	5.8e-07	33.0
WP_168219126.1\|5161538_5162285_-\|transposase	transposase	NA	NA	NA	NA
WP_168219127.1\|5162246_5162672_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149112026.1\|5162559_5163684_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149112027.1\|5163782_5165429_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
5166151:5166165	attR	NA	NA	NA	NA

DBSCAN-SWA_14

5195810 : 5240084

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149112069.1\|5195810_5196308_+\|transposase	transposase	NA	NA	NA	NA
WP_149112070.1\|5197427_5197844_-	hypothetical protein	NA	NA	NA	NA
WP_149112071.1\|5198371_5198725_+	hypothetical protein	NA	NA	NA	NA
WP_149112072.1\|5198721_5199030_-	hypothetical protein	NA	NA	NA	NA
WP_149112073.1\|5199654_5199936_-	hypothetical protein	NA	NA	NA	NA
WP_149112074.1\|5200013_5200571_-	SgcJ/EcaC family oxidoreductase	NA	NA	NA	NA
WP_168218808.1\|5200907_5202036_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149112075.1\|5202504_5203206_-	hypothetical protein	NA	NA	NA	NA
WP_149112076.1\|5203476_5204082_+\|transposase	transposase	NA	NA	NA	NA
WP_149112077.1\|5205306_5206131_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_168219137.1\|5206277_5206910_-	class I SAM-dependent methyltransferase	A0A1P8DJL8	Virus_Rctr41k	6.8e-45	43.2
WP_149112079.1\|5211476_5212028_+	hypothetical protein	NA	NA	NA	NA
WP_149112080.1\|5212070_5213321_+	glycosyltransferase	NA	NA	NA	NA
WP_149112081.1\|5213459_5214308_-	amidinotransferase	NA	NA	NA	NA
WP_149112082.1\|5214385_5215621_-	TIGR00300 family protein	NA	NA	NA	NA
WP_149112083.1\|5215832_5215958_-\|transposase	transposase domain-containing protein	NA	NA	NA	NA
WP_149112084.1\|5215992_5217603_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_149112085.1\|5217816_5218374_+	peroxidase-related enzyme	NA	NA	NA	NA
WP_149112086.1\|5218463_5219078_+	DUF417 family protein	NA	NA	NA	NA
WP_149115584.1\|5219122_5219578_+	DUF1348 family protein	NA	NA	NA	NA
WP_149112087.1\|5219610_5220489_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_149112088.1\|5220505_5221126_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_149112089.1\|5221137_5221785_+	isochorismatase family protein	NA	NA	NA	NA
WP_149112090.1\|5221852_5222800_+	catalase	NA	NA	NA	NA
WP_149112091.1\|5222816_5224109_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_149112092.1\|5224343_5224796_+	VOC family protein	NA	NA	NA	NA
WP_149112093.1\|5224899_5225787_-	hypothetical protein	NA	NA	NA	NA
WP_149112094.1\|5226050_5227415_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_149112095.1\|5227411_5228803_-	histidine kinase	B5LWA6	Feldmannia_species_virus	1.0e-05	32.4
WP_149112096.1\|5228813_5230076_-	anion transporter	NA	NA	NA	NA
WP_149112097.1\|5230089_5231139_-	hypothetical protein	NA	NA	NA	NA
WP_149112098.1\|5231135_5232356_-	MFS transporter	NA	NA	NA	NA
WP_149112099.1\|5232352_5234116_-	hypothetical protein	NA	NA	NA	NA
WP_149112100.1\|5234123_5234651_-	hypothetical protein	NA	NA	NA	NA
WP_149112101.1\|5234647_5235985_-	MFS transporter	NA	NA	NA	NA
WP_149112102.1\|5236523_5237327_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_168219138.1\|5237555_5237711_-	hypothetical protein	NA	NA	NA	NA
WP_149112103.1\|5238088_5238526_+	hypothetical protein	NA	NA	NA	NA
WP_149109166.1\|5238851_5240084_-\|transposase	IS701 family transposase	NA	NA	NA	NA

DBSCAN-SWA_15

5442189 : 5501595

Bacillus_phage(50.0%)

integrase,transposase

attL 5436332:5436348|attR 5480287:5480303

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5436332:5436348	attL	NA	NA	NA	NA
WP_168219153.1\|5442189_5442645_-\|transposase	transposase	NA	NA	NA	NA
WP_168219154.1\|5442672_5444007_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149112285.1\|5444016_5444220_+	hypothetical protein	NA	NA	NA	NA
WP_149112286.1\|5444273_5444594_-	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_149112287.1\|5444795_5444984_+	hypothetical protein	NA	NA	NA	NA
WP_149115592.1\|5445798_5446107_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149110580.1\|5446451_5447060_-	hypothetical protein	NA	NA	NA	NA
WP_149110579.1\|5447188_5448565_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149112288.1\|5449122_5449521_+	hypothetical protein	NA	NA	NA	NA
WP_149112289.1\|5449553_5449946_+	hypothetical protein	NA	NA	NA	NA
WP_149112290.1\|5450472_5450856_-	hypothetical protein	NA	NA	NA	NA
WP_149112291.1\|5450955_5451411_+	hypothetical protein	NA	NA	NA	NA
WP_149112292.1\|5451721_5451931_+	hypothetical protein	NA	NA	NA	NA
WP_149112293.1\|5452172_5453147_+	hypothetical protein	NA	NA	NA	NA
WP_149112294.1\|5453143_5454469_+	AAA family ATPase	O80281	Escherichia_phage	1.3e-58	37.4
WP_168219155.1\|5454651_5454864_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149112296.1\|5454890_5456453_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149112297.1\|5456589_5456901_+	hypothetical protein	NA	NA	NA	NA
WP_149112298.1\|5456959_5457343_-	glyoxalase	NA	NA	NA	NA
WP_149112299.1\|5457239_5458697_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168219156.1\|5458811_5459636_+	response regulator	NA	NA	NA	NA
WP_149112301.1\|5459717_5460200_-	fasciclin domain-containing protein	NA	NA	NA	NA
WP_149112302.1\|5460931_5461168_+	hypothetical protein	NA	NA	NA	NA
WP_149112303.1\|5461239_5462472_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_168218711.1\|5462985_5463144_-	hypothetical protein	NA	NA	NA	NA
WP_168219525.1\|5466093_5467329_+	response regulator	W8CYF6	Bacillus_phage	1.2e-21	27.1
WP_149112305.1\|5467549_5469067_+	AAA family ATPase	NA	NA	NA	NA
WP_149112306.1\|5469059_5470598_+	response regulator	W8CYF6	Bacillus_phage	1.5e-21	28.5
WP_149112307.1\|5470716_5471112_+	hypothetical protein	NA	NA	NA	NA
WP_168219157.1\|5471381_5471945_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_168219158.1\|5472166_5473678_+	response regulator	W8CYF6	Bacillus_phage	5.5e-16	27.6
WP_149112310.1\|5473786_5474041_-	hypothetical protein	NA	NA	NA	NA
WP_149112311.1\|5475277_5475559_-	hypothetical protein	NA	NA	NA	NA
WP_149112312.1\|5475655_5475874_-	hypothetical protein	NA	NA	NA	NA
WP_149112315.1\|5476479_5478795_+	catalase/peroxidase HPI	NA	NA	NA	NA
WP_168218712.1\|5479017_5479254_+	hypothetical protein	NA	NA	NA	NA
WP_149112316.1\|5479806_5481087_-	DUF2254 domain-containing protein	NA	NA	NA	NA
5480287:5480303	attR	NA	NA	NA	NA
WP_149112317.1\|5481083_5482358_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.8e-52	51.7
WP_149112318.1\|5482378_5483407_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_168219159.1\|5483435_5483834_-	response regulator	NA	NA	NA	NA
WP_149112320.1\|5483830_5485399_-	trehalose-6-phosphate synthase	NA	NA	NA	NA
WP_149112321.1\|5485664_5487176_+	histidine kinase	A0A1V0SGX0	Hokovirus	1.0e-09	26.0
WP_149112322.1\|5487182_5488616_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_149112323.1\|5488729_5489560_+	hypothetical protein	NA	NA	NA	NA
WP_149112324.1\|5489914_5490163_-	hypothetical protein	NA	NA	NA	NA
WP_149115593.1\|5490159_5490759_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149112325.1\|5490976_5492386_+	beta-propeller fold lactonase family protein	NA	NA	NA	NA
WP_149112326.1\|5492407_5492992_+	hypothetical protein	NA	NA	NA	NA
WP_149112327.1\|5492988_5493240_+	hypothetical protein	NA	NA	NA	NA
WP_149112328.1\|5493289_5493988_+	thiosulfate reductase	NA	NA	NA	NA
WP_149112329.1\|5493959_5494706_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_149112330.1\|5494734_5495292_+	redoxin domain-containing protein	NA	NA	NA	NA
WP_168219160.1\|5495965_5496898_-	hypothetical protein	NA	NA	NA	NA
WP_149115594.1\|5496911_5497199_-	hypothetical protein	NA	NA	NA	NA
WP_149112332.1\|5497833_5498355_-	hypothetical protein	NA	NA	NA	NA
WP_149112333.1\|5498344_5501080_+	hypothetical protein	NA	NA	NA	NA
WP_149112334.1\|5501163_5501595_+\|transposase	transposase family protein	NA	NA	NA	NA

DBSCAN-SWA_16

5508066 : 5536650

Ralstonia_phage(20.0%)

integrase,transposase,protease

attL 5524915:5524934|attR 5537891:5537910

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168219071.1\|5508066_5509332_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149112344.1\|5509492_5509762_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149109721.1\|5509860_5510889_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168219161.1\|5511257_5512475_+	DUF4339 domain-containing protein	NA	NA	NA	NA
WP_149112346.1\|5512500_5513301_-	hypothetical protein	NA	NA	NA	NA
WP_149112347.1\|5513559_5513778_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149112348.1\|5513761_5514826_-\|integrase	tyrosine-type recombinase/integrase	A0A221SAN4	Ralstonia_phage	1.5e-12	27.7
WP_149112349.1\|5515257_5515395_+\|transposase	transposase	NA	NA	NA	NA
WP_168219162.1\|5515982_5520065_-	AAA family ATPase	NA	NA	NA	NA
WP_149112351.1\|5520272_5520971_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	7.3e-16	42.1
WP_149112352.1\|5521113_5521692_-	hypothetical protein	NA	NA	NA	NA
WP_149115595.1\|5521785_5522856_-	esterase family protein	NA	NA	NA	NA
WP_149112353.1\|5523692_5527805_-	protein kinase	M1HTX6	Paramecium_bursaria_Chlorella_virus	5.6e-15	27.4
5524915:5524934	attL	NA	NA	NA	NA
WP_149112354.1\|5528051_5528897_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	4.5e-36	38.2
WP_149112355.1\|5529155_5531084_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_168219163.1\|5531271_5534022_-	protein kinase	Q8JE84	Murine_leukemia_virus	1.5e-11	25.9
WP_149112357.1\|5535309_5536650_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
5537891:5537910	attR	NA	NA	NA	NA

DBSCAN-SWA_17

6386999 : 6502196

112

Paramecium_bursaria_Chlorella_virus(22.22%)

transposase,tRNA,protease,portal,integrase,capsid

attL 6393023:6393038|attR 6495936:6495953

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149113000.1\|6386999_6388085_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_149113001.1\|6388134_6388569_+	hypothetical protein	NA	NA	NA	NA
WP_149113002.1\|6388573_6389704_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.1e-24	29.1
WP_168219223.1\|6389724_6391836_-	acetylxylan esterase	NA	NA	NA	NA
WP_149113004.1\|6391897_6392140_-	hypothetical protein	NA	NA	NA	NA
WP_149113005.1\|6392191_6392890_-	YHS domain-containing protein	NA	NA	NA	NA
WP_149113006.1\|6392991_6394305_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
6393023:6393038	attL	NA	NA	NA	NA
WP_149113007.1\|6396721_6398137_-	hypothetical protein	NA	NA	NA	NA
6393023:6393038	attL	NA	NA	NA	NA
WP_149113008.1\|6398763_6399468_+	hypothetical protein	NA	NA	NA	NA
WP_149113009.1\|6399880_6400195_+	hypothetical protein	NA	NA	NA	NA
WP_149113010.1\|6401335_6402202_+	hypothetical protein	NA	NA	NA	NA
WP_149113011.1\|6402198_6402558_+	hypothetical protein	NA	NA	NA	NA
WP_149113012.1\|6402557_6402818_+	hypothetical protein	NA	NA	NA	NA
WP_149113013.1\|6402814_6403009_+	hypothetical protein	NA	NA	NA	NA
WP_149113014.1\|6403005_6403293_+	hypothetical protein	NA	NA	NA	NA
WP_149113015.1\|6403289_6403685_+	hypothetical protein	NA	NA	NA	NA
WP_149113016.1\|6403681_6403936_+	hypothetical protein	NA	NA	NA	NA
WP_149113017.1\|6404005_6404227_+	hypothetical protein	NA	NA	NA	NA
WP_149113018.1\|6404289_6404493_+	hypothetical protein	NA	NA	NA	NA
WP_149113019.1\|6404518_6404758_+	hypothetical protein	NA	NA	NA	NA
WP_149113020.1\|6404806_6405241_+	hypothetical protein	NA	NA	NA	NA
WP_149113021.1\|6405281_6405674_+	hypothetical protein	NA	NA	NA	NA
WP_149113022.1\|6405802_6406036_+	hypothetical protein	NA	NA	NA	NA
WP_149113023.1\|6406452_6407562_-	acyltransferase family protein	W6MVL2	Pseudomonas_phage	8.4e-06	30.6
WP_149113024.1\|6407630_6408155_-	hypothetical protein	NA	NA	NA	NA
WP_149113025.1\|6408148_6409717_-	collagen-like protein	NA	NA	NA	NA
WP_149113026.1\|6409713_6409977_-	hypothetical protein	NA	NA	NA	NA
WP_149113027.1\|6410099_6410504_-	hypothetical protein	NA	NA	NA	NA
WP_149113028.1\|6410500_6410956_-	cytochrome c	NA	NA	NA	NA
WP_149113029.1\|6410982_6412443_-	hypothetical protein	NA	NA	NA	NA
WP_168219224.1\|6412442_6413159_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_149113031.1\|6413198_6413405_-	hypothetical protein	NA	NA	NA	NA
WP_149113032.1\|6413434_6413950_-	hypothetical protein	NA	NA	NA	NA
WP_149113033.1\|6414017_6414383_-	hypothetical protein	NA	NA	NA	NA
WP_168219225.1\|6414379_6414574_-	hypothetical protein	NA	NA	NA	NA
WP_149113034.1\|6415596_6416496_-	hypothetical protein	NA	NA	NA	NA
WP_149113035.1\|6416499_6418074_-	hypothetical protein	NA	NA	NA	NA
WP_149113036.1\|6418364_6418724_-	hypothetical protein	NA	NA	NA	NA
WP_149113037.1\|6418726_6419161_-	hypothetical protein	NA	NA	NA	NA
WP_149113038.1\|6419167_6419611_-	hypothetical protein	NA	NA	NA	NA
WP_149113039.1\|6419603_6419933_-	hypothetical protein	NA	NA	NA	NA
WP_149113040.1\|6419932_6420514_-	hypothetical protein	NA	NA	NA	NA
WP_149113041.1\|6420583_6422008_-\|capsid	phage major capsid protein	NA	NA	NA	NA
WP_149113042.1\|6422088_6422649_-	hypothetical protein	NA	NA	NA	NA
WP_149113043.1\|6422645_6423878_-\|portal	phage portal protein	K7PJU5	Enterobacteria_phage	5.0e-36	28.5
WP_149113044.1\|6423892_6425527_-	hypothetical protein	A0A0S2GLF0	Bacillus_phage	1.0e-28	23.5
WP_149113045.1\|6425530_6425788_-	hypothetical protein	NA	NA	NA	NA
WP_149113046.1\|6425787_6426105_-	hypothetical protein	NA	NA	NA	NA
WP_149113047.1\|6426275_6426674_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_149113048.1\|6426663_6427545_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168219226.1\|6427981_6428539_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168219227.1\|6428535_6428841_-	hypothetical protein	NA	NA	NA	NA
6428694:6428709	attR	NA	NA	NA	NA
WP_149109721.1\|6429345_6430374_-\|transposase	IS110 family transposase	NA	NA	NA	NA
6428694:6428709	attR	NA	NA	NA	NA
WP_149111051.1\|6430505_6431666_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_168219026.1\|6431662_6431821_+	hypothetical protein	NA	NA	NA	NA
WP_149109721.1\|6431912_6432941_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149113050.1\|6435047_6435993_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149113051.1\|6435990_6436272_-\|transposase	transposase	NA	NA	NA	NA
WP_149113052.1\|6436262_6436583_-\|transposase	transposase	NA	NA	NA	NA
WP_149113053.1\|6436622_6437294_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_149113054.1\|6437352_6437685_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168219228.1\|6437903_6438059_+	hypothetical protein	NA	NA	NA	NA
WP_149113055.1\|6438879_6439242_+	hypothetical protein	NA	NA	NA	NA
WP_149115639.1\|6439853_6440141_+	hypothetical protein	NA	NA	NA	NA
WP_149113056.1\|6440332_6440911_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_149115640.1\|6440973_6441942_+	phosphatidylserine decarboxylase family protein	NA	NA	NA	NA
WP_149113057.1\|6441946_6442807_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_168219229.1\|6443182_6443326_+	hypothetical protein	NA	NA	NA	NA
WP_149113058.1\|6443331_6443541_+	hypothetical protein	NA	NA	NA	NA
WP_149113059.1\|6443702_6444092_-	hypothetical protein	NA	NA	NA	NA
WP_168219230.1\|6444108_6444654_-	hypothetical protein	NA	NA	NA	NA
WP_149113061.1\|6444605_6444797_-	hypothetical protein	NA	NA	NA	NA
WP_168219231.1\|6444878_6445031_-	hypothetical protein	NA	NA	NA	NA
WP_168219232.1\|6446260_6446542_+	hypothetical protein	NA	NA	NA	NA
WP_149113063.1\|6446910_6447597_-	hypothetical protein	NA	NA	NA	NA
WP_149113064.1\|6447614_6448796_-	hypothetical protein	NA	NA	NA	NA
WP_149113065.1\|6448960_6450403_+	cytochrome c	NA	NA	NA	NA
WP_149113066.1\|6450402_6451491_+	hypothetical protein	NA	NA	NA	NA
WP_149113067.1\|6451879_6454612_-	tetratricopeptide repeat protein	S4VV57	Pandoravirus	2.6e-16	27.5
WP_149113068.1\|6454661_6457691_-	tetratricopeptide repeat protein	M1HXD9	Paramecium_bursaria_Chlorella_virus	1.5e-12	25.8
WP_149113069.1\|6457787_6458384_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149113070.1\|6458495_6460253_+	sugar hydrolase	M1GX90	Paramecium_bursaria_Chlorella_virus	2.9e-61	36.5
WP_168219233.1\|6460445_6460595_+	hypothetical protein	NA	NA	NA	NA
WP_149113071.1\|6461336_6461621_-	hypothetical protein	NA	NA	NA	NA
WP_149113072.1\|6462138_6464733_-	hypothetical protein	NA	NA	NA	NA
WP_149113073.1\|6464799_6465081_-	hypothetical protein	NA	NA	NA	NA
WP_168219234.1\|6465383_6466886_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_149113075.1\|6467021_6467966_-	hypothetical protein	NA	NA	NA	NA
WP_149113076.1\|6468001_6469894_-	3-oxoacyl-ACP synthase	NA	NA	NA	NA
WP_149113077.1\|6470548_6470821_+	hypothetical protein	NA	NA	NA	NA
WP_168219235.1\|6470842_6472702_-	hypothetical protein	NA	NA	NA	NA
WP_149113079.1\|6473964_6485391_+	tandem-95 repeat protein	NA	NA	NA	NA
WP_149111049.1\|6485561_6485885_-	hypothetical protein	NA	NA	NA	NA
WP_149113080.1\|6485878_6486307_-\|transposase	transposase	NA	NA	NA	NA
WP_168219236.1\|6486410_6487109_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149109026.1\|6487024_6487531_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149113081.1\|6487645_6488473_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_149109721.1\|6488735_6489764_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168219026.1\|6489855_6490014_-	hypothetical protein	NA	NA	NA	NA
WP_149111051.1\|6490010_6491171_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_149109721.1\|6491302_6492331_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168219237.1\|6492754_6493051_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149113083.1\|6492977_6493532_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149113084.1\|6493699_6493936_-	hypothetical protein	NA	NA	NA	NA
WP_149113085.1\|6494771_6495125_+	hypothetical protein	NA	NA	NA	NA
WP_149113086.1\|6495207_6495459_+	hypothetical protein	NA	NA	NA	NA
WP_149113087.1\|6495455_6497222_+	hypothetical protein	F5A3A4	Riemerella_phage	3.9e-21	30.8
WP_168219238.1\|6497221_6497377_+	hypothetical protein	NA	NA	NA	NA
WP_168219239.1\|6497557_6500239_-	protein kinase	A0A2H4UW49	Bodo_saltans_virus	1.1e-11	29.0
WP_149113089.1\|6500723_6501161_+	response regulator	NA	NA	NA	NA
WP_168218752.1\|6501366_6501774_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_149108426.1\|6501716_6502196_+\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_18

6606968 : 6637268

Pseudomonas_phage(16.67%)

transposase,plate,coat,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149113178.1\|6606968_6608093_-\|plate	baseplate protein	B3GAJ9	uncultured_virus	8.6e-59	44.6
WP_149113179.1\|6608098_6608464_-\|tail	phage tail protein	NA	NA	NA	NA
WP_149113180.1\|6608466_6609093_-	hypothetical protein	NA	NA	NA	NA
WP_149113181.1\|6609089_6610196_-	phage late control D family protein	NA	NA	NA	NA
WP_149113182.1\|6610182_6610371_-	hypothetical protein	NA	NA	NA	NA
WP_149113183.1\|6610374_6611163_-	hypothetical protein	NA	NA	NA	NA
WP_149113184.1\|6611159_6612947_-	hypothetical protein	K4NZX3	Burkholderia_phage	1.4e-79	38.8
WP_149113185.1\|6612939_6613452_-	hypothetical protein	NA	NA	NA	NA
WP_149113186.1\|6613622_6614015_-	hypothetical protein	NA	NA	NA	NA
WP_149113187.1\|6614023_6614455_-	hypothetical protein	NA	NA	NA	NA
WP_149113188.1\|6614474_6616007_-\|tail	phage tail protein	B3GAJ6	uncultured_virus	2.9e-105	47.3
WP_149113189.1\|6616013_6616193_-	hypothetical protein	NA	NA	NA	NA
WP_149113190.1\|6616210_6617047_-	hypothetical protein	NA	NA	NA	NA
WP_149113191.1\|6617063_6617372_-	hypothetical protein	NA	NA	NA	NA
WP_149113192.1\|6617401_6618067_-	hypothetical protein	NA	NA	NA	NA
WP_149113193.1\|6618074_6618467_-	hypothetical protein	NA	NA	NA	NA
WP_168219246.1\|6618473_6618650_-	hypothetical protein	NA	NA	NA	NA
WP_149113194.1\|6618705_6619878_-\|coat	P22 coat - protein 5 family protein	G8C7P7	Escherichia_phage	2.7e-87	46.4
WP_149115647.1\|6619972_6620749_-	hypothetical protein	A0A0S2SY92	Pseudomonas_phage	2.0e-59	55.9
WP_149113195.1\|6620855_6622247_-	DUF4055 domain-containing protein	A0A0H5AWC7	Pseudomonas_phage	3.3e-100	44.7
WP_149113196.1\|6622249_6623683_-	hypothetical protein	A0A2I7RHB5	Vibrio_phage	4.9e-83	50.9
WP_149113197.1\|6623824_6624004_+	hypothetical protein	NA	NA	NA	NA
WP_149113198.1\|6624000_6624183_+	hypothetical protein	NA	NA	NA	NA
WP_149113199.1\|6624184_6624499_+	hypothetical protein	NA	NA	NA	NA
WP_149113200.1\|6624495_6625032_-\|terminase	terminase small subunit	A0A1W6JNT5	Morganella_phage	7.1e-27	38.0
WP_149113201.1\|6625199_6625688_-	hypothetical protein	NA	NA	NA	NA
WP_149113202.1\|6625875_6626193_-	hypothetical protein	NA	NA	NA	NA
WP_149113203.1\|6626189_6626969_-	ATP-binding protein	K7PLU3	Enterobacteria_phage	1.1e-44	42.5
WP_149113204.1\|6626965_6627712_-	hypothetical protein	B5AX23	Iodobacteriophage	8.9e-20	49.5
WP_149113205.1\|6627879_6628188_-	hypothetical protein	K4I378	Acinetobacter_phage	2.2e-25	58.2
WP_149113206.1\|6628180_6628408_-	hypothetical protein	NA	NA	NA	NA
WP_149113207.1\|6628404_6628611_-	hypothetical protein	NA	NA	NA	NA
WP_149115648.1\|6628745_6629771_+	hypothetical protein	A0A2I7RPX6	Vibrio_phage	5.3e-07	31.2
WP_149113208.1\|6629796_6631014_+	hypothetical protein	A0A077KCC0	Edwardsiella_phage	2.7e-18	44.6
WP_168218808.1\|6630920_6632049_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149113209.1\|6632183_6633110_+	AAA family ATPase	V5YUP8	Pseudomonas_phage	7.4e-56	42.4
WP_149113210.1\|6633131_6633557_+	single-stranded DNA-binding protein	A0A0U2C0X4	Paracoccus_phage	2.3e-41	62.0
WP_149113211.1\|6633931_6634225_+	DUF2312 domain-containing protein	A0A0F6R615	Sinorhizobium_phage	6.0e-20	55.3
WP_149113212.1\|6634415_6634625_-	hypothetical protein	NA	NA	NA	NA
WP_149113213.1\|6634621_6635035_-	hypothetical protein	NA	NA	NA	NA
WP_168219247.1\|6635278_6635452_-	hypothetical protein	NA	NA	NA	NA
WP_149113214.1\|6635758_6636046_+	hypothetical protein	NA	NA	NA	NA
WP_149113215.1\|6636247_6636607_+	hypothetical protein	NA	NA	NA	NA
WP_149113216.1\|6636606_6636870_+	hypothetical protein	NA	NA	NA	NA
WP_149113217.1\|6636866_6637268_+	hypothetical protein	A0A2H5BPW3	Vibrio_phage	1.3e-38	60.0

DBSCAN-SWA_19

7052259 : 7165004

Bacillus_phage(37.5%)

integrase,transposase,terminase,protease

attL 7074365:7074424|attR 7088965:7091192

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168219295.1\|7052259_7053495_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_149113563.1\|7053559_7053880_-	DUF1580 domain-containing protein	NA	NA	NA	NA
WP_149113564.1\|7054177_7054735_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149113565.1\|7054731_7055625_-	hypothetical protein	NA	NA	NA	NA
WP_149113566.1\|7055624_7056656_-	hypothetical protein	NA	NA	NA	NA
WP_149113567.1\|7056658_7057147_-	hypothetical protein	NA	NA	NA	NA
WP_168219296.1\|7057532_7057754_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_149113569.1\|7058150_7058750_+	hypothetical protein	NA	NA	NA	NA
WP_149110579.1\|7059157_7060534_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149110580.1\|7060662_7061271_+	hypothetical protein	NA	NA	NA	NA
WP_149113570.1\|7061588_7061936_-	hypothetical protein	NA	NA	NA	NA
WP_149113571.1\|7062105_7062495_+	hypothetical protein	NA	NA	NA	NA
WP_149113572.1\|7062707_7063106_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_168219297.1\|7063232_7063976_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_149113574.1\|7064170_7064437_-	hypothetical protein	NA	NA	NA	NA
WP_168218808.1\|7064558_7065687_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149113575.1\|7065792_7065993_-	hypothetical protein	NA	NA	NA	NA
WP_149113576.1\|7066107_7066443_-	hypothetical protein	NA	NA	NA	NA
WP_149113577.1\|7066692_7066908_+	hypothetical protein	NA	NA	NA	NA
WP_149113578.1\|7067163_7067472_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149113579.1\|7067620_7067968_+	hypothetical protein	NA	NA	NA	NA
WP_149113580.1\|7068044_7068845_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149113581.1\|7068979_7071502_+	hypothetical protein	D6PFQ5	uncultured_phage	1.7e-14	35.0
WP_149113582.1\|7071585_7072113_+	hypothetical protein	NA	NA	NA	NA
WP_149113583.1\|7072147_7072534_+	hypothetical protein	NA	NA	NA	NA
WP_168219298.1\|7073102_7074035_-	DUF1559 domain-containing protein	NA	NA	NA	NA
7074365:7074424	attL	NA	NA	NA	NA
WP_149110579.1\|7074432_7075809_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149110580.1\|7075937_7076546_+	hypothetical protein	NA	NA	NA	NA
WP_149115663.1\|7076701_7076947_-	hypothetical protein	NA	NA	NA	NA
WP_149113585.1\|7078151_7078367_-	hypothetical protein	NA	NA	NA	NA
WP_149113586.1\|7078389_7078671_-	hypothetical protein	NA	NA	NA	NA
WP_149113587.1\|7078768_7079110_-	hypothetical protein	NA	NA	NA	NA
WP_168219299.1\|7079221_7079722_-	DUF4142 domain-containing protein	NA	NA	NA	NA
WP_149113589.1\|7079868_7080255_-	response regulator	NA	NA	NA	NA
WP_149113590.1\|7080348_7080528_-	hypothetical protein	NA	NA	NA	NA
WP_149113591.1\|7080704_7080950_-	hypothetical protein	NA	NA	NA	NA
WP_149113592.1\|7081547_7082852_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149113593.1\|7083124_7083472_+	DUF1016 family protein	NA	NA	NA	NA
WP_149113594.1\|7083954_7084791_+	hypothetical protein	NA	NA	NA	NA
WP_149113595.1\|7084895_7085219_+	hypothetical protein	NA	NA	NA	NA
WP_149113596.1\|7085299_7088008_+	DUF3854 domain-containing protein	NA	NA	NA	NA
WP_149113597.1\|7088253_7088928_+\|terminase	terminase small subunit	NA	NA	NA	NA
WP_149110579.1\|7089032_7090409_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149110580.1\|7090537_7091146_+	hypothetical protein	NA	NA	NA	NA
WP_168218714.1\|7091370_7091832_+	hypothetical protein	NA	NA	NA	NA
7088965:7091192	attR	NA	NA	NA	NA
WP_149113598.1\|7092006_7092309_+	hypothetical protein	NA	NA	NA	NA
WP_149113599.1\|7092329_7093721_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_149113600.1\|7093735_7096279_-	DUF1549 domain-containing protein	NA	NA	NA	NA
WP_149113601.1\|7096283_7097174_-	esterase family protein	NA	NA	NA	NA
WP_149113602.1\|7097279_7098659_-	hypothetical protein	NA	NA	NA	NA
WP_149113603.1\|7098655_7099336_-	response regulator	W8CYM9	Bacillus_phage	9.6e-21	33.5
WP_149113604.1\|7099493_7099778_-	hypothetical protein	NA	NA	NA	NA
WP_149115664.1\|7100383_7100659_-	hypothetical protein	NA	NA	NA	NA
WP_149113605.1\|7101167_7101341_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_149113606.1\|7101361_7102030_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_149113607.1\|7102122_7102788_+	O-methyltransferase	NA	NA	NA	NA
WP_149113608.1\|7102987_7103374_-	hypothetical protein	NA	NA	NA	NA
WP_149113609.1\|7103496_7106196_+	FAD-binding protein	NA	NA	NA	NA
WP_149113610.1\|7106761_7107919_-	hypothetical protein	NA	NA	NA	NA
WP_149109721.1\|7108736_7109765_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149113611.1\|7110021_7110309_-	hypothetical protein	NA	NA	NA	NA
WP_149113612.1\|7110808_7112989_-	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_149113613.1\|7115026_7115668_+\|transposase	transposase	NA	NA	NA	NA
WP_168219300.1\|7116194_7117121_+	hypothetical protein	NA	NA	NA	NA
WP_149113615.1\|7117141_7117654_+	hypothetical protein	NA	NA	NA	NA
WP_149113616.1\|7117769_7125434_-	cadherin-like domain-containing protein	NA	NA	NA	NA
WP_149113617.1\|7125481_7126558_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149113618.1\|7126715_7128776_+	hypothetical protein	NA	NA	NA	NA
WP_149113619.1\|7129682_7130036_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_149113620.1\|7130076_7139343_+	cadherin-like domain-containing protein	NA	NA	NA	NA
WP_149113621.1\|7139834_7140236_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_149113622.1\|7141817_7142045_+	hypothetical protein	NA	NA	NA	NA
WP_149113623.1\|7142087_7142645_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_149113624.1\|7142583_7143123_+\|transposase	transposase	NA	NA	NA	NA
WP_168219301.1\|7144016_7144175_+	hypothetical protein	NA	NA	NA	NA
WP_149113625.1\|7144438_7144816_+	hypothetical protein	NA	NA	NA	NA
WP_168218808.1\|7144929_7146058_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149113626.1\|7146886_7151311_+	DUF4465 domain-containing protein	NA	NA	NA	NA
WP_149113627.1\|7151399_7152410_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149113628.1\|7152759_7153758_-	ribonucleotide-diphosphate reductase subunit beta	A0A0P0YMB5	Yellowstone_lake_phycodnavirus	1.6e-48	33.1
WP_149115665.1\|7153778_7156094_-	ribonucleoside-diphosphate reductase subunit alpha	E5ERT4	Ostreococcus_lucimarinus_virus	7.7e-179	45.1
WP_149113629.1\|7156673_7157489_-\|transposase	transposase	NA	NA	NA	NA
WP_149113630.1\|7157971_7158325_+	hypothetical protein	NA	NA	NA	NA
WP_149113631.1\|7158327_7158660_+	hypothetical protein	NA	NA	NA	NA
WP_149113632.1\|7158656_7161695_+	hypothetical protein	D6PGG3	uncultured_phage	1.1e-12	32.6
WP_149113633.1\|7161876_7162425_+	DUF1579 family protein	NA	NA	NA	NA
WP_149113634.1\|7162575_7163037_+	thioredoxin family protein	NA	NA	NA	NA
WP_149113635.1\|7163218_7163644_-	hypothetical protein	NA	NA	NA	NA
WP_149113636.1\|7163949_7164186_+	hypothetical protein	NA	NA	NA	NA
WP_149113637.1\|7164239_7164383_-	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_149115666.1\|7164572_7165004_-\|protease	SprT family zinc-dependent metalloprotease	A0A1D8EZB9	Mycobacterium_phage	1.1e-25	41.9

DBSCAN-SWA_20

7233203 : 7276842

Vibrio_phage(15.0%)

integrase,transposase,terminase

attL 7249992:7250008|attR 7279145:7279161

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149113716.1\|7233203_7233656_-	single-stranded DNA-binding protein	A0A0K1LLZ9	Caulobacter_phage	3.4e-38	58.7
WP_149111503.1\|7233866_7234673_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_149113717.1\|7234807_7235266_-	hypothetical protein	A0A1B1IQ32	uncultured_Mediterranean_phage	9.7e-09	31.7
WP_149113718.1\|7235399_7236365_-	phage recombination protein Bet	A0A2K9VEY5	Mycobacterium_phage	3.0e-07	24.3
WP_168219311.1\|7236364_7236868_-	hypothetical protein	NA	NA	NA	NA
WP_168219312.1\|7237055_7237403_-	hypothetical protein	NA	NA	NA	NA
WP_149113720.1\|7237549_7238020_+	GIY-YIG nuclease family protein	A0A024FSJ1	Bacillus_phage	3.4e-09	37.4
WP_149113721.1\|7238148_7238409_+	hypothetical protein	NA	NA	NA	NA
WP_149113722.1\|7238398_7238749_+	DUF1064 domain-containing protein	A0A0U2C0S3	Paracoccus_phage	8.7e-10	39.6
WP_149113723.1\|7238745_7239207_+	hypothetical protein	NA	NA	NA	NA
WP_149113724.1\|7239363_7240203_+	DUF1376 domain-containing protein	A0A2H4FS76	Methylophilaceae_phage	3.0e-16	28.6
WP_149113725.1\|7240180_7240510_+	hypothetical protein	NA	NA	NA	NA
WP_168219313.1\|7240511_7240889_+	DUF3775 domain-containing protein	NA	NA	NA	NA
WP_149113727.1\|7240885_7241176_+	hypothetical protein	NA	NA	NA	NA
WP_168219314.1\|7241159_7241408_+	hypothetical protein	NA	NA	NA	NA
WP_149113728.1\|7242045_7243335_-	hypothetical protein	NA	NA	NA	NA
WP_149113729.1\|7243532_7244009_+	hypothetical protein	NA	NA	NA	NA
WP_149113730.1\|7244374_7244953_+\|terminase	terminase small subunit	I2GUC2	Acinetobacter_phage	5.7e-14	53.9
WP_149113731.1\|7244888_7246328_+	DNA packaging protein	C8CLI4	Xylella_phage	8.5e-160	63.6
WP_149113732.1\|7246344_7248486_+	hypothetical protein	A0A2I7RQ11	Vibrio_phage	7.8e-93	35.2
WP_149113733.1\|7248485_7250297_+	hypothetical protein	A0A0F7L7R5	uncultured_marine_virus	1.1e-07	39.4
7249992:7250008	attL	NA	NA	NA	NA
WP_149113734.1\|7250416_7250830_+	hypothetical protein	NA	NA	NA	NA
WP_149113735.1\|7250906_7251797_+	hypothetical protein	NA	NA	NA	NA
WP_149113736.1\|7251813_7253043_+	hypothetical protein	A0A1B1IR95	uncultured_Mediterranean_phage	1.5e-67	40.6
WP_149113737.1\|7253103_7253595_+	hypothetical protein	NA	NA	NA	NA
WP_149113738.1\|7253599_7253914_+	hypothetical protein	NA	NA	NA	NA
WP_149113739.1\|7253917_7254610_+	hypothetical protein	I3PUX2	Vibrio_phage	2.2e-28	34.8
WP_149113740.1\|7254613_7256062_+	hypothetical protein	A0A0E3JSB2	Rhodoferax_phage	3.2e-58	32.3
WP_149113741.1\|7256058_7256493_+	hypothetical protein	NA	NA	NA	NA
WP_149113742.1\|7256496_7257936_+	hypothetical protein	A0A2I7RHN0	Vibrio_phage	2.6e-07	38.1
WP_149113743.1\|7257948_7259328_+	hypothetical protein	NA	NA	NA	NA
WP_149113744.1\|7259327_7261979_+	lytic transglycosylase domain-containing protein	A0A2D1GR13	Pseudomonas_phage	3.8e-12	34.0
WP_149113745.1\|7262003_7262336_+	hypothetical protein	NA	NA	NA	NA
WP_149113746.1\|7262365_7263751_+	hypothetical protein	NA	NA	NA	NA
WP_149113747.1\|7263747_7264101_+	hypothetical protein	NA	NA	NA	NA
WP_149113748.1\|7264097_7264589_+	hypothetical protein	K4PBB0	Acinetobacter_phage	4.3e-23	39.6
WP_149113749.1\|7264591_7264852_+	hypothetical protein	NA	NA	NA	NA
WP_149113750.1\|7264855_7265278_+	hypothetical protein	A0A2H4FY72	Methylophilaceae_phage	2.7e-21	49.3
WP_168219315.1\|7265274_7265448_+	hypothetical protein	NA	NA	NA	NA
WP_149113751.1\|7265678_7266884_-	DNA (cytosine-5-)-methyltransferase	I6NLI4	Burkholderia_phage	1.1e-56	37.4
WP_149113752.1\|7266973_7267228_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149113753.1\|7267337_7268108_+	hypothetical protein	NA	NA	NA	NA
WP_149113755.1\|7268954_7270160_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149115672.1\|7270522_7270840_-	hypothetical protein	A0A0K1LP53	Klebsiella_phage	6.9e-14	44.9
WP_149113756.1\|7271217_7272342_+	hypothetical protein	NA	NA	NA	NA
WP_149113757.1\|7272424_7272679_+	hypothetical protein	NA	NA	NA	NA
WP_149113758.1\|7272665_7273148_+	hypothetical protein	NA	NA	NA	NA
WP_168218808.1\|7273149_7274278_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.4e-18	25.8
WP_149113759.1\|7274387_7274996_+\|transposase	transposase	NA	NA	NA	NA
WP_149115673.1\|7275906_7276149_-	hypothetical protein	NA	NA	NA	NA
WP_168219316.1\|7276653_7276842_+\|transposase	transposase family protein	NA	NA	NA	NA
7279145:7279161	attR	NA	NA	NA	NA

DBSCAN-SWA_21

7385563 : 7452861

Microcystis_phage(20.0%)

integrase,transposase,plate,protease

attL 7433987:7434005|attR 7454301:7454319

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149113844.1\|7385563_7386046_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_149113845.1\|7386066_7387911_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_149113846.1\|7387874_7389038_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_168219329.1\|7389052_7389910_+	formylglycine-generating enzyme family protein	A0A075BSL8	Microcystis_phage	2.1e-36	35.2
WP_149113848.1\|7389989_7390370_+	response regulator	NA	NA	NA	NA
WP_149113849.1\|7390366_7391497_+	response regulator	Q6XM27	Feldmannia_irregularis_virus	4.4e-10	27.2
WP_149113850.1\|7391508_7392276_+	P-loop NTPase	F0PIG8	Enterococcus_phage	6.4e-05	24.2
WP_149115679.1\|7392288_7392717_-	EamA family transporter	NA	NA	NA	NA
WP_149113851.1\|7392740_7394207_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_149113852.1\|7394203_7395253_-	Na+-dependent transporter	NA	NA	NA	NA
WP_149113853.1\|7395255_7395939_-	response regulator	NA	NA	NA	NA
WP_149113854.1\|7395955_7397650_-	hypothetical protein	NA	NA	NA	NA
WP_149113855.1\|7397676_7398171_-	hypothetical protein	NA	NA	NA	NA
WP_149113856.1\|7398472_7399912_+	TonB-dependent receptor	NA	NA	NA	NA
WP_149113857.1\|7399998_7401366_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_149113858.1\|7401369_7403058_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_149113859.1\|7403175_7411179_-	hypothetical protein	NA	NA	NA	NA
WP_149113860.1\|7411355_7412336_-	response regulator	Q56AR1	Bacillus_thuringiensis_phage	6.3e-05	32.8
WP_168219535.1\|7412599_7415035_-	hypothetical protein	NA	NA	NA	NA
WP_149113861.1\|7415625_7416462_-	creatininase family protein	NA	NA	NA	NA
WP_168219330.1\|7416729_7419570_+	peptidase	NA	NA	NA	NA
WP_149113863.1\|7419613_7420837_+	cyanophycinase	NA	NA	NA	NA
WP_149113864.1\|7420964_7421699_+	lipid-binding SYLF domain-containing protein	NA	NA	NA	NA
WP_149113865.1\|7421956_7422361_+	hypothetical protein	NA	NA	NA	NA
WP_149113866.1\|7422602_7422863_-	hypothetical protein	NA	NA	NA	NA
WP_168219331.1\|7423259_7423685_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_168218716.1\|7423594_7423990_+	hypothetical protein	NA	NA	NA	NA
WP_149113869.1\|7424080_7424368_-	EF-hand domain-containing protein	NA	NA	NA	NA
WP_149113870.1\|7424598_7425627_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_149113871.1\|7425776_7427408_-	VCBS repeat-containing protein	NA	NA	NA	NA
WP_149113872.1\|7428103_7428508_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149115681.1\|7428624_7428897_-	hypothetical protein	NA	NA	NA	NA
WP_149113873.1\|7429466_7429931_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_149113874.1\|7430535_7431435_-\|transposase	transposase	NA	NA	NA	NA
WP_168219332.1\|7431965_7432400_-	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_149113876.1\|7432551_7432827_-	hypothetical protein	NA	NA	NA	NA
WP_149113877.1\|7433054_7433264_-	hypothetical protein	NA	NA	NA	NA
7433987:7434005	attL	NA	NA	NA	NA
WP_149113878.1\|7434229_7435042_-	hypothetical protein	NA	NA	NA	NA
WP_149113879.1\|7435550_7436336_+	hypothetical protein	NA	NA	NA	NA
WP_149113880.1\|7436433_7436643_+	hypothetical protein	NA	NA	NA	NA
WP_168219333.1\|7436854_7437979_+	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
WP_168219334.1\|7437975_7439748_+	DEAD/DEAH box helicase	A0A2D1GP10	Streptomyces_phage	5.2e-34	30.7
WP_149113882.1\|7439750_7440218_+	hypothetical protein	NA	NA	NA	NA
WP_149113883.1\|7440844_7441282_+	hypothetical protein	NA	NA	NA	NA
WP_168219335.1\|7441278_7441590_+	DUF1580 domain-containing protein	NA	NA	NA	NA
WP_149113885.1\|7441586_7441979_+	hypothetical protein	NA	NA	NA	NA
WP_149113886.1\|7441981_7442329_+	hypothetical protein	NA	NA	NA	NA
WP_149113887.1\|7442390_7442768_+	hypothetical protein	NA	NA	NA	NA
WP_149113888.1\|7442794_7443103_+	hypothetical protein	NA	NA	NA	NA
WP_149113889.1\|7443139_7445206_+	hypothetical protein	NA	NA	NA	NA
WP_149113890.1\|7445202_7445571_-	hypothetical protein	NA	NA	NA	NA
WP_149113891.1\|7445533_7445887_-	hypothetical protein	NA	NA	NA	NA
WP_149113892.1\|7445987_7447319_-	hypothetical protein	NA	NA	NA	NA
WP_149113893.1\|7447852_7449106_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149113894.1\|7449363_7450101_-	RraA family protein	NA	NA	NA	NA
WP_149113895.1\|7450305_7450713_+	hypothetical protein	NA	NA	NA	NA
WP_149113896.1\|7450788_7452861_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
7454301:7454319	attR	NA	NA	NA	NA

DBSCAN-SWA_22

7938195 : 7986110

Acanthocystis_turfacea_Chlorella_virus(25.0%)

integrase,transposase

attL 7938039:7938082|attR 7973670:7973713

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
7938039:7938082	attL	NA	NA	NA	NA
WP_149114238.1\|7938195_7939437_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149114239.1\|7939570_7939936_+	hypothetical protein	NA	NA	NA	NA
WP_149114240.1\|7940455_7941763_+	protein kinase	M1HGF9	Acanthocystis_turfacea_Chlorella_virus	3.7e-21	36.8
WP_149114241.1\|7941855_7942533_+	hypothetical protein	NA	NA	NA	NA
WP_149114242.1\|7942529_7944596_-	hypothetical protein	NA	NA	NA	NA
WP_149114243.1\|7944632_7944941_-	hypothetical protein	NA	NA	NA	NA
WP_149114244.1\|7944967_7945345_-	hypothetical protein	NA	NA	NA	NA
WP_149114245.1\|7945406_7945793_-	hypothetical protein	NA	NA	NA	NA
WP_149114246.1\|7945756_7946149_-	hypothetical protein	NA	NA	NA	NA
WP_149114247.1\|7946145_7946457_-	DUF1580 domain-containing protein	NA	NA	NA	NA
WP_149114248.1\|7946453_7946888_-	hypothetical protein	NA	NA	NA	NA
WP_149114249.1\|7947522_7948122_-	hypothetical protein	NA	NA	NA	NA
WP_149114250.1\|7948114_7949770_-	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	1.4e-49	31.7
WP_149114251.1\|7949766_7950804_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_149114252.1\|7950955_7951162_-	hypothetical protein	NA	NA	NA	NA
WP_149114253.1\|7951263_7952082_-	hypothetical protein	NA	NA	NA	NA
WP_149114254.1\|7952284_7952968_-	hypothetical protein	NA	NA	NA	NA
WP_149114255.1\|7953431_7953677_-	hypothetical protein	NA	NA	NA	NA
WP_149114256.1\|7954143_7954692_+	hypothetical protein	NA	NA	NA	NA
WP_168219375.1\|7954731_7954890_+	hypothetical protein	NA	NA	NA	NA
WP_149114257.1\|7954928_7955156_-	hypothetical protein	NA	NA	NA	NA
WP_149114258.1\|7955202_7955511_-	ArsR family transcriptional regulator	NA	NA	NA	NA
WP_149114259.1\|7955835_7956489_-	hypothetical protein	NA	NA	NA	NA
WP_149114260.1\|7956686_7957142_-	hypothetical protein	NA	NA	NA	NA
WP_149114261.1\|7957501_7957735_-	hypothetical protein	NA	NA	NA	NA
WP_149115412.1\|7957772_7958018_-	hypothetical protein	NA	NA	NA	NA
WP_149108794.1\|7958583_7959708_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_149114262.1\|7959704_7960223_-	hypothetical protein	NA	NA	NA	NA
WP_149114263.1\|7960410_7960749_+	hypothetical protein	NA	NA	NA	NA
WP_149114264.1\|7960850_7961408_-	hypothetical protein	NA	NA	NA	NA
WP_149114265.1\|7961554_7961980_-	hypothetical protein	NA	NA	NA	NA
WP_149114266.1\|7962140_7962527_-	hypothetical protein	NA	NA	NA	NA
WP_149114267.1\|7962775_7963387_+	hypothetical protein	NA	NA	NA	NA
WP_149114268.1\|7963623_7964562_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149114269.1\|7964597_7965020_-	hypothetical protein	NA	NA	NA	NA
WP_149114270.1\|7965363_7966305_-	hypothetical protein	NA	NA	NA	NA
WP_149114271.1\|7966309_7966534_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149114272.1\|7966726_7967161_-	hypothetical protein	NA	NA	NA	NA
WP_168219376.1\|7967228_7967369_-	hypothetical protein	NA	NA	NA	NA
WP_149114273.1\|7967423_7967810_-	hypothetical protein	NA	NA	NA	NA
WP_168219377.1\|7967908_7968181_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149114275.1\|7968244_7968721_+	macro domain-containing protein	A0A2L1IVW3	Streptomyces_phage	2.8e-27	45.2
WP_149114276.1\|7968991_7972006_+	PAS domain S-box protein	NA	NA	NA	NA
WP_149114277.1\|7972393_7973131_+	hypothetical protein	NA	NA	NA	NA
WP_149114278.1\|7973149_7973374_-	hypothetical protein	NA	NA	NA	NA
WP_149114279.1\|7974081_7974513_+	hypothetical protein	NA	NA	NA	NA
7973670:7973713	attR	NA	NA	NA	NA
WP_149114280.1\|7974633_7975041_-	hypothetical protein	NA	NA	NA	NA
WP_149114282.1\|7976325_7976583_-\|transposase	transposase	NA	NA	NA	NA
WP_168219378.1\|7976656_7977487_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.6e-25	44.8
WP_149114284.1\|7977483_7977954_+	hypothetical protein	NA	NA	NA	NA
WP_149114285.1\|7979143_7979749_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_149114286.1\|7979745_7980240_+	cupin domain-containing protein	NA	NA	NA	NA
WP_149114287.1\|7980278_7981661_+	MATE family efflux transporter	NA	NA	NA	NA
WP_149114288.1\|7981741_7981876_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149114289.1\|7982013_7984452_-	VCBS repeat-containing protein	NA	NA	NA	NA
WP_168219379.1\|7985280_7985688_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_149108426.1\|7985630_7986110_+\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_23

8818808 : 8889787

Acidithiobacillus_phage(60.0%)

transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168219461.1\|8818808_8819702_-\|transposase	transposase	NA	NA	NA	NA
WP_149114947.1\|8819805_8821200_+	hypothetical protein	NA	NA	NA	NA
WP_149114948.1\|8821429_8821777_+	hypothetical protein	NA	NA	NA	NA
WP_149114949.1\|8821915_8822449_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149114950.1\|8822441_8825141_+	hypothetical protein	NA	NA	NA	NA
WP_149114951.1\|8825915_8826911_-	hypothetical protein	NA	NA	NA	NA
WP_149114952.1\|8826941_8829122_-	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_149114953.1\|8829283_8831854_+	hypothetical protein	NA	NA	NA	NA
WP_149114954.1\|8833054_8834362_+	ParB N-terminal domain-containing protein	K4HZA5	Acidithiobacillus_phage	2.4e-76	42.0
WP_149114955.1\|8834318_8835005_-	hypothetical protein	NA	NA	NA	NA
WP_168219462.1\|8835235_8835694_-	hypothetical protein	NA	NA	NA	NA
WP_149114958.1\|8835779_8835995_+	hypothetical protein	NA	NA	NA	NA
WP_149115736.1\|8836149_8836716_+	RNA polymerase subunit sigma	NA	NA	NA	NA
WP_149114959.1\|8837545_8838070_+	hypothetical protein	NA	NA	NA	NA
WP_149114960.1\|8838481_8838772_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149109166.1\|8839281_8840514_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_149114961.1\|8840553_8841138_-	hypothetical protein	NA	NA	NA	NA
WP_149110579.1\|8841266_8842643_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_149114962.1\|8843090_8844068_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_168219463.1\|8844703_8845783_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_149114963.1\|8846737_8847583_-	hypothetical protein	NA	NA	NA	NA
WP_149114964.1\|8848020_8848257_+	hypothetical protein	NA	NA	NA	NA
WP_149115738.1\|8848615_8848900_+\|coat	spore coat protein	NA	NA	NA	NA
WP_149114965.1\|8848977_8850633_+	S8 family serine peptidase	NA	NA	NA	NA
WP_149114966.1\|8851019_8851205_-	hypothetical protein	NA	NA	NA	NA
WP_149114967.1\|8851613_8851820_+	hypothetical protein	NA	NA	NA	NA
WP_149114968.1\|8851863_8852379_+	DUF2924 domain-containing protein	NA	NA	NA	NA
WP_149114969.1\|8852375_8853962_+	recombinase family protein	K4ICM1	Acidithiobacillus_phage	3.4e-77	43.7
WP_149114970.1\|8853958_8854381_+	hypothetical protein	NA	NA	NA	NA
WP_149114971.1\|8854528_8855725_+	hypothetical protein	NA	NA	NA	NA
WP_149114972.1\|8855681_8856731_+	hypothetical protein	NA	NA	NA	NA
WP_149114973.1\|8856993_8857326_+	hypothetical protein	NA	NA	NA	NA
WP_168219464.1\|8857453_8857966_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149114975.1\|8858081_8860712_+	AAA family ATPase	NA	NA	NA	NA
WP_149114976.1\|8860829_8862008_+	ParB N-terminal domain-containing protein	K4HZA5	Acidithiobacillus_phage	7.6e-90	47.9
WP_149114977.1\|8862000_8862528_+	hypothetical protein	NA	NA	NA	NA
WP_149114978.1\|8862636_8863026_+	hypothetical protein	NA	NA	NA	NA
WP_149114979.1\|8863022_8863259_+	hypothetical protein	NA	NA	NA	NA
WP_149114980.1\|8863272_8863557_+	hypothetical protein	NA	NA	NA	NA
WP_149114981.1\|8863792_8872399_-	cadherin-like domain-containing protein	NA	NA	NA	NA
WP_149114982.1\|8872597_8872804_+	hypothetical protein	NA	NA	NA	NA
WP_149114983.1\|8872992_8874219_+	hypothetical protein	NA	NA	NA	NA
WP_149114984.1\|8874655_8874859_+	hypothetical protein	NA	NA	NA	NA
WP_149114985.1\|8875113_8877369_-	PAS domain S-box protein	B5LWN8	Feldmannia_species_virus	4.0e-07	36.3
WP_149114986.1\|8877373_8877814_-	response regulator	NA	NA	NA	NA
WP_168219465.1\|8877807_8881167_-	PAS domain S-box protein	W8CYF6	Bacillus_phage	5.6e-13	24.6
WP_168219466.1\|8881459_8881870_+	hypothetical protein	NA	NA	NA	NA
WP_168219467.1\|8881866_8882316_+	response regulator	NA	NA	NA	NA
WP_168219468.1\|8882639_8882780_+	hypothetical protein	NA	NA	NA	NA
WP_149115739.1\|8883316_8884636_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_149114989.1\|8885073_8885268_-	Fis family transcriptional regulator	NA	NA	NA	NA
WP_149114990.1\|8885912_8886512_+	DUF4291 family protein	NA	NA	NA	NA
WP_149114991.1\|8886633_8887164_+	hypothetical protein	NA	NA	NA	NA
WP_168219469.1\|8887345_8887834_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_168219470.1\|8887864_8888485_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_149114995.1\|8889380_8889581_+	hypothetical protein	NA	NA	NA	NA
WP_168219471.1\|8889577_8889787_-\|transposase	IS110 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042425

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection