CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP030848	Sphingobacterium hotanense strain AMCC101218 chromosome, complete genome	24 crisprs	csa3,cas3,RT,PD-DExK,DEDDh,WYL	2	5	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP030848_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_1

1019045-1019128

Orphan

Consensus_repeat	Method
ATTTTCTGAACCAGGAAAGGAAGGATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_1

>merge|NZ_CP030848|1|1019045-1019128|CRISPRCasFinder
ATTTTCTGAACCAGGAAAGGAAGGATGCAAGGATGGGCAGGATCTTGTAGAAGGGTAATTTTCTGAACCAAGAAAGGAAGGATG

>NZ_CP030848|1|1|1019045-1019128|CRISPRCasFinder
ATTTTCTGAACCAGGAAAGGAAGGATG	CAAGGATGGGCAGGATCTTGTAGAAGGGTA
ATTTTCTGAACCAAGAAAGGAAGGATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149524987.1\|1016834_1018067_-\|cation:dicarboxylase-symporter-family-transporter	unknown	unknown	gnl\|CDD\|366058
NZ_CP030848.1\|WP_149524996.1\|1029018_1030200_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|379337
NZ_CP030848.1\|WP_149524984.1\|1011922_1012684_-\|DUF2520-domain-containing-protein	unknown	unknown	gnl\|CDD\|378484
NZ_CP030848.1\|WP_149524986.1\|1015176_1015581_-\|cytochrome-c-maturation-protein-CcmE	unknown	unknown	gnl\|CDD\|376989
NZ_CP030848.1\|WP_149524994.1\|1026734_1027769_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|366154
NZ_CP030848.1\|WP_149524993.1\|1025461_1026721_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149524983.1\|1010181_1011735_-\|FMN-binding-glutamate-synthase-family-protein	unknown	unknown	gnl\|CDD\|239202
NZ_CP030848.1\|WP_149524985.1\|1012683_1015152_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|224061
NZ_CP030848.1\|WP_149524990.1\|1022126_1022627_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223976
NZ_CP030848.1\|WP_149524981.1\|1009159_1009603_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149524992.1\|1024678_1025164_-\|phosphohistidine-phosphatase	unknown	unknown	gnl\|CDD\|224973
NZ_CP030848.1\|WP_149524988.1\|1018130_1018808_+\|tRNA-(5-methylaminomethyl-2-thiouridine)(34)-methyltransferase-MnmD	unknown	unknown	gnl\|CDD\|226606
NZ_CP030848.1\|WP_149524980.1\|1008377_1009154_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|143599
NZ_CP030848.1\|WP_149524991.1\|1022647_1024657_-\|DUF255-domain-containing-protein	unknown	unknown	gnl\|CDD\|224250
NZ_CP030848.1\|WP_149524997.1\|1030222_1031038_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133042
NZ_CP030848.1\|WP_149524979.1\|1007329_1008307_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|173833
NZ_CP030848.1\|WP_149524982.1\|1009723_1010164_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP030848.1\|WP_149524989.1\|1019368_1020277_+\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526622.1\|1020437_1021886_+\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|377531
NZ_CP030848.1\|WP_149524995.1\|1027765_1029013_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340847

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149524987.1\|1016834_1018067_-\|cation:dicarboxylase-symporter-family-transporter	gnl\|CDD\|366058	pfam00375, SDF, Sodium:dicarboxylate symporter family.	9.58678e-71
NZ_CP030848.1\|WP_149524996.1\|1029018_1030200_+\|glycosyltransferase	gnl\|CDD\|379337	pfam13692, Glyco_trans_1_4, Glycosyl transferases group 1.	3.09647e-15
NZ_CP030848.1\|WP_149524984.1\|1011922_1012684_-\|DUF2520-domain-containing-protein	gnl\|CDD\|378484	pfam10728, DUF2520, Domain of unknown function (DUF2520). This presumed domain is found C-terminal to a Rossmann-like domain suggesting that these proteins are oxidoreductases.	4.97849e-43
NZ_CP030848.1\|WP_149524986.1\|1015176_1015581_-\|cytochrome-c-maturation-protein-CcmE	gnl\|CDD\|376989	pfam03100, CcmE, CcmE. CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c biosynthesis in eubacteria. Expression of these proteins is induced when the organisms are grown under anaerobic conditions with nitrate or nitrite as the final electron acceptor.	7.90241e-17
NZ_CP030848.1\|WP_149524994.1\|1026734_1027769_+\|glycosyltransferase	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.42503e-33
NZ_CP030848.1\|WP_149524983.1\|1010181_1011735_-\|FMN-binding-glutamate-synthase-family-protein	gnl\|CDD\|239202	cd02808, GltS_FMN, Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast and bacterial pathway for ammonia assimilation. It is a multifunctional enzyme that functions through three distinct active centers, carrying out L-glutamine hydrolysis, conversion of 2-oxoglutarate into L-glutamate, and electron uptake from an electron donor.	2.05023e-166
NZ_CP030848.1\|WP_149524985.1\|1012683_1015152_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|224061	COG1138, CcmF, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones].	3.00468e-73
NZ_CP030848.1\|WP_149524990.1\|1022126_1022627_-\|peptidylprolyl-isomerase	gnl\|CDD\|223976	COG1047, SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones].	5.32399e-42
NZ_CP030848.1\|WP_149524992.1\|1024678_1025164_-\|phosphohistidine-phosphatase	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	4.5884e-26
NZ_CP030848.1\|WP_149524988.1\|1018130_1018808_+\|tRNA-(5-methylaminomethyl-2-thiouridine)(34)-methyltransferase-MnmD	gnl\|CDD\|226606	COG4121, COG4121, Uncharacterized conserved protein [Function unknown].	1.29388e-28
NZ_CP030848.1\|WP_149524980.1\|1008377_1009154_+\|amidohydrolase	gnl\|CDD\|143599	cd07575, Xc-1258_like, Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases). Uncharacterized subgroup belonging to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup either represents a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. XC1258 is a homotetramer.	3.02301e-157
NZ_CP030848.1\|WP_149524991.1\|1022647_1024657_-\|DUF255-domain-containing-protein	gnl\|CDD\|224250	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP030848.1\|WP_149524997.1\|1030222_1031038_-\|glycosyltransferase	gnl\|CDD\|133042	cd06420, GT2_Chondriotin_Pol_N, N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase. Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.	8.31081e-92
NZ_CP030848.1\|WP_149524979.1\|1007329_1008307_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|173833	cd00685, Trans_IPPS_HT, Trans-Isoprenyl Diphosphate Synthases, head-to-tail. These trans-Isoprenyl Diphosphate Synthases (Trans_IPPS) catalyze head-to-tail (HT) (1'-4) condensation reactions. This CD includes all-trans (E)-isoprenyl diphosphate synthases which synthesize various chain length (C10, C15, C20, C25, C30, C35, C40, C45, and C50) linear isoprenyl diphosphates from precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). They catalyze the successive 1'-4 condensation of the 5-carbon IPP to allylic substrates geranyl-, farnesyl-, or geranylgeranyl-diphosphate. Isoprenoid chain elongation reactions proceed via electrophilic alkylations in which a new carbon-carbon single bond is generated through interaction between a highly reactive electron-deficient allylic carbocation and an electron-rich carbon-carbon double bond. The catalytic site consists of a large central cavity formed by mostly antiparallel alpha helices with two aspartate-rich regions (DDXX(XX)D) located on opposite walls. These residues mediate binding of prenyl phosphates via bridging Mg2+ ions, inducing proposed conformational changes that close the active site to solvent, protecting and stabilizing reactive carbocation intermediates. Farnesyl diphosphate synthases produce the precursors of steroids, cholesterol, sesquiterpenes, farnsylated proteins, heme, and vitamin K12; and geranylgeranyl diphosphate and longer chain synthases produce the precursors of carotenoids, retinoids, diterpenes, geranylgeranylated chlorophylls, ubiquinone, and archaeal ether linked lipids. Isoprenyl diphosphate synthases are widely distributed among archaea, bacteria, and eukareya.	1.52594e-92
NZ_CP030848.1\|WP_149524982.1\|1009723_1010164_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.00958e-16
NZ_CP030848.1\|WP_149526622.1\|1020437_1021886_+\|IS1182-family-transposase	gnl\|CDD\|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	6.73829e-13
NZ_CP030848.1\|WP_149524995.1\|1027765_1029013_+\|glycosyltransferase	gnl\|CDD\|340847	cd03820, GT4_AmsD-like, amylovoran biosynthesis glycosyltransferase AmsD and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.	1.21492e-66

>NZ_CP030848.1|WP_149524988.1|1018130_1018808_+|tRNA-(5-methylaminomethyl-2-thiouridine)(34)-methyltransferase-MnmD
MEFVKTDDGSKTLYQAEVGEHYHSKHGAHQESIHVFLNTGLRFFLEKEQTTQASILEVGFGTGLNFLLTADYCRKSEITLDYCGIEAYPLPLSLISQSEYNQYIDASLWDAFLDHYEAALIDKTNILPHIDLQIAHQKLMDFHPDQLFDVLYFDAFAEIHQPEMWTVEALAHVCQFLKPGGVFVTYAITGNLKRAMKSIGFSIEKAPGAPGKREMLRAVKLDSRY
>NZ_CP030848.1|WP_149524987.1|1016834_1018067_-|cation:dicarboxylase-symporter-family-transporter
MNKVLQNYGSIIWLLVGITIGSLIGVFYPSAVDVLKPVGDIFLNLLFVSVIPLLFFAISSSIANIEDSKTLGKTISIMTIVFISTIVIAAVATIFGLWTFPVTALQDSNALTDALPSNPEDTWGDRIVRFLSVDEFANLLSRKSILAFVIFSLLVGVATRRSGEMGKQFTQFLNAGNKVMENLLTLIMKAGPIGLGAYFAFQVKTLGPELFGFYAKPLGFYYVFGMIFFLVFFSLYAFIAKGPSGIPLFWKHNIAPSLTALSTCSSLATLPANLLAAKRIGIPHNIASIVIPLGNTLYKNGSAISSILKIYVAFSILQWDFFEPTTLITAVGITVLVSMVAGGIPNGGFIGEMLMISIYGIPNEAVPSILIIGALVDPLATVLNATADTVAAMLVTRFSGEKFEAESAEA
>NZ_CP030848.1|WP_149524986.1|1015176_1015581_-|cytochrome-c-maturation-protein-CcmE
MKKSSIILIGIIAIAIAMILVIYTDSSTYSTFTEAKEKNTELYVVGVLNKEKALHYDPVTDANHFSFYMYDNDSTECQVVFNGSKPQDIERSEQIVLTGKMEGNTFHASKILMKCPSKYNQDQMEVIETSSAAL
>NZ_CP030848.1|WP_149524985.1|1012683_1015152_-|cytochrome-c-biogenesis-protein-CcsA
MDVNYVGENLLPGQIGQFFVVLSFGAALFSFISYFFASKNPEVTSWRTMGRIGFWLNALSIAVIGGTLFYIIYNHLFEYHYAYAHSSTKLPTHYIISAFWEGQEGSFWLWMFWQAVLGTVLVFKAKSWESPVMTFVMLCQVFLASMLLGVEVFGSRIGSSPFILLRDALNFPFLKNANYLSMIPDGRGLNPLLQNYWMVIHPPTLFLGFASMIVPFAYAASGLWLKRFKDWINPGLPWALFAVMILGAGIIMGSFWAYEALNFGGFWAWDPVENVSIIPWLTLIAAVHVMVAFKNTGHAYFTSAFLCLISFVLVIYASYLTRSGILGETSVHSFTSLGMSGQLILFNLTFLVIMIVVLVFRKKEMPSTQKEEDIYSREFWLFIGALVLTVACVQMIATTSIPVFNALFGTKVAPPIDPIPHYNKWQGAFAVVVMTLTAFTQFLKYKRSDAKKFWASTLASFIIALVLSAVIVYFTKVYGNIMYILITFSSVFAILANLQILADSFKGKWRLAGSAVSHIGFGLLLIGALIAAATNEVISVNSSNYIAVAGFDQVEKPGENLFLTEGEPVQMGEYKITYVGDSVAAPNVFYKINYERIDEETGAVKESFVLMPFAQNNPQMGGLIGTPGTKHFLTHDIYTLITAAASDSQAAVNQEEDASERSSFDEYEEPATYEVNIGDTLRYRNGYYIIDAINKNATISNIPKEEGDVLVGMQIRVVASDGKEFKAEPIFMIKGGNTMDFHKDVPEQGLRFRFSNIMPDKNKLELIAYQKPLPEKKWVVFKAIKFPYINFFWCGTIVMTIGFCMAIYRRLKDSRISKVKTS
>NZ_CP030848.1|WP_149524984.1|1011922_1012684_-|DUF2520-domain-containing-protein
MNIVLIGSGNIASTWGKALAALGHHITQIYSHTLANAHALANSLSSLATDKLEELDLTADLYIVAVSDSAIPSVVEQMLQHLAGLVIHCSGATDIKALSGFKRFGVVYPVQSFSKTVAINFNKIPFGIEANTAEDEALLQGLFSELSSNVFPCSSEQRLAIHLAAVMVNNFSNALYQMAYELLEQKNLSFDLMRPIILETAEKVQNHVPKDVQTGPAIRNDDVTINKHLQFISDNPEWQSIYQQITSLIKKRG
>NZ_CP030848.1|WP_149524983.1|1010181_1011735_-|FMN-binding-glutamate-synthase-family-protein
MQVRKLILGTIILINLIIISFGIIFTPRWFWLLLIPFPLLIIALYHSFQTSHAILRNYPLVGYFRYFFESIRPELRQYFWESDTDGRPFNRRQRSLVYQRAKNQRETVAFGMQSDPQAVGNEWAAHSIFPVHIEDHNLRTMVGNSQCKQPYSLSVFNISAMSYGALSRTAITALNKGAALQNFAHNTGEGGISQYHISGGDLIWQVGTGYFGCRDENGFFSPELYREKSTRPYVKMIELKLSQGAKPGHGGILPAAKNTPEVAAIRHVVPGTDVMSPPAHSAFRTPVEMMHFIQQLRELSDGKPVGFKLCIGDKNEFLDICHAMQETQIMPDFISVDGSEGGTGAAPLEFTDNLGMPLYDALAFVTTTLINYGLKKHIKIIVSSRIVTGFDILKVIALGADACYSARGMMFALGCIQALKCNEDVCPVGVATQQPHLYKGLDVQDKYVRVAQFHRNTLRATVEIMEACGFKTLEDVSADKFFRKVDSQNTLSFQDIYFKNTGKLVNNRSDFAPEVFD
>NZ_CP030848.1|WP_149524982.1|1009723_1010164_+|MarR-family-transcriptional-regulator
MDVANMYQDEFYSFLTGRVSTAIGRRLQRNFKQIGLNITAEQWSILYFLWDSEGLSQQDLARLTFRDKPSISRLISNLEKQKLLVRVSGSGDRRTNQIYLTAQGHRIKDKCMAQAEKTISEAMEGVDRDSMRQAQQILEIVFNNLK
>NZ_CP030848.1|WP_149524981.1|1009159_1009603_-|hypothetical-protein
METILTILLVVGGILYKIYENYKEEMEKSRKRMQERMKQMQPPAPTPQPQSMKSAQKQQEAKPIVLRVERKRDEIPPIPVYQSEVREIDEVELAHQQRLARQMKQRQAQQQQQQALALVEEHSNIQGEFDLRRAIIQQAILERPYKD
>NZ_CP030848.1|WP_149524980.1|1008377_1009154_+|amidohydrolase
MEPLKITIFQAYLFWENVDKNLQNLSLRLSALREKTDLIILPEMFNTGFTTNVEKCAETMSGKTMHWLYETSKKFDCVIAGTLIIEEEGKYYNRFIWMSPDGSYVHYDKRHLFSMANEDKVFTPGQSRVILPLKGWKICPMICYDLRFPIWSRNQNGAYDLLVYTASWPDKRSQHWRALIPARAIENQAFVIGVNRVGHDGNEVYYSGGSMCINPNGDVVYYKPEDEDLYTFTIYPKDLEENRDRFPFLDDQDQFKIL
>NZ_CP030848.1|WP_149524979.1|1007329_1008307_+|polyprenyl-synthetase-family-protein
MFETHPYSTLVSQYLQERSFPQTPAYLYDPIRYILSLSGKRIRPMLALMGARLFGKENLQEVLPASCAIEYFHNFSLIHDDIMDKAPLRRGKPTVHMQWNDNVAILSGDALLVKAYEELAYCPADKIPALLRVFNQVALEVCEGQQLDMDFENMEIVSEQAYLNMIKLKTSVLLGGALKMGAILSDASEEQQQLIYDFGVNLGIAFQLQDDFLDVYGDPSSFGKQVGGDILCDKKTILRIRTQQLAEGENKEELQNLLFPNQLSDEEKITRMKKLYSTLAVDEYTNQLKEEYMQLAYNQLSAIGVPEANKAELFALADMLMNRVK
>NZ_CP030848.1|WP_149524989.1|1019368_1020277_+|transposase
MINQARALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLGIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVIEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSKVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149526622.1|1020437_1021886_+|IS1182-family-transposase
MLSTQQKIQFSSYSGLYDIIVPKDNLLRKINDLIDFSFIYDELLAKYCQTNGRTAESPIKMFKYLLLKTIYTVSDVDVVERSRYDMSFKYFLEMAPEEDVINSSSLTKFRKLRLKDMDLLNLLINRTVTIALEKGIIKSKSIIVDATHTVSRSNPHTALAVLRERSKLLRKAIYQIDGEYKRNLPQKNESNDLDQELAYCRELQRVLDEDQSISEIPAVKEKLNLLKETIEDTKEYYLLSKDDEARLGHKSVDSSFFGYKTHLAMTEERIITAAVVTTGEKGDGPELPRLLEISQQNGMQVDTIIGDAAYSGKENLQVAKEQNIDIIAKLNPSITQGFRKDKDKFDYNKDADMFVCPAGHLAIRKARQGKKEQGTNQTETYYFDVEKCKVCPLREGCYKQGARTKSYSVSIKSELHREQMAFQQTDYYRSKSKQRYKIEAKNSELKNVHGYGRADAYGIHNMEMQGAMAIFTVNLKRILKLI
>NZ_CP030848.1|WP_149524990.1|1022126_1022627_-|peptidylprolyl-isomerase
MAVENNNVVTLNYVLHTIEENGEKTFVEQTTSDNPLTFLYGVGMMLPKFEENIAGLNAGDKTSFELEPNDAYGERDDKAIAQLPAEMFQEVGLPPVGEVIPLQDNQGNQFRAVVIEVTPETVVADLNHPMAGKKLNFDIEVIASRPATADELSHGHAHGIDGNEAH
>NZ_CP030848.1|WP_149524991.1|1022647_1024657_-|DUF255-domain-containing-protein
MANKLQNENSPYLQQHAHNPVQWYPWGEEALKKAKEENKLIIISVGYSACHWCHVMERESFENDAIAQTMNKFFVSIKVDREERPDIDQIYMIAVQLMTNAGGWPLNCICLPDGRPIYGGTYFKPQDWQNVLLQIAKMWEETPEVALDYADRLTKGIQQAEKLPIQEIPEAYTKQDLLNIVDPWIETFDQNEGGYRRTPKFPLPNNWSFLLRYGALSKDQAILDHVHFTLEKIANGGIYDQIGGGFARYSVDNRWHIPHFEKMLYDNGQLLSLYSEAYQQKPTILYKRVVEETIAWAEREMLDPNGGFYSALDADSEGIEGKFYSFDYDEFDILGDRADLARNYFHISKNGNWTEEQTNVPYLSADDNQLIAEAGYSEYEWEEELKSIKETLLNYRKQRIRPGLDHKQLVTWNALMIKGLVDAYRTFRNDHYLNLAKQTAEFIWTKCHENDILLHQPADSNRSIPGFLDDYGFSIESFISLYEATFDETWINRAKTLTEQAINIFYDKDERTFFYTSSHGEELIARKSEIMDNVIPGSVSTMVRQLYKLGILFDEEQYTLIADQVFANVFPHIKSYGSAYSNWAIQLLELHYGIWEIALTGADASEWREELDQYYIPNKVTLGGTKSSLPLLEHKAGMESKAYLCQNKTCSLPQTSIAQIIELINNKQG
>NZ_CP030848.1|WP_149524992.1|1024678_1025164_-|phosphohistidine-phosphatase
MKTLYLIRHAKAEDHGLLKNDYNRNIISKGKERAIRIANELATQLKIDSNTLVISSSANRAKQTADIFCEILGYPLADIQETKEIYEAHFIDILRIINGMPNKVDKLLVFGHNPGLSNLTNYLSHAEVDLATSNVAILTLPDNFNFSELAGGTATLLNTIQ
>NZ_CP030848.1|WP_149524993.1|1025461_1026721_+|hypothetical-protein
MLFNKTVLRFGAFTLILFLTACARGEMELFPEEIPEKVGRKDFTIDLQVNIFPQQVNIDMLANGNYPRYVKPEFIKNIGYNNSSYCHPDVQYFPDGFQGYKYWMVFTPYFGAIGGDQLAKRYENPTIVVSNDGLNWVEPAGIVNPIQACPGYKESFREMQGEQIQGFWSDVDWLFEGGEFQLYYRGSFLSAKALSARGAKSQNNRAKLIKNARRTIVRQTSRDGVHWDPLEAVMYSDVPYSPKNSHMLSPSFLKVGEGYVSYEVELNSGKKHFKQDKPSFVIQRSSTNGLDFSRFSNSKIVNFINEPWIRQNRDNGPWHLQASYVDGFYFLCIAVGDVKKYTADQLYLAFSNDGLNFYVCPKPIITEDAYRSAIFPKTVDEKAVQFGAILGYKTGVFKYAEMSLQWAQMQELIDNKMDR
>NZ_CP030848.1|WP_149524994.1|1026734_1027769_+|glycosyltransferase
MLERNDILISIIIPVYNREAFIGQAIESVLGQSVVDFELWVVDDGSKDRTSDIVQGYAQRDARVNYVYQENAGVSVARNVGLSRAGGKYVYFLDSDDALDFEFLRTSIDVIERSAADVVVVGQPYQDRLPHPTALPTCGQLWRHAFLKQNSTVRFPVGVQPGEDGLFSHCLLAMTDRIAANPAGIYYYGRHEGQNHLLINRDCESVLQQMDKWFTYLDDFYSRESLFERRALHLAKFLEHEPFELRYLLMPFNAEQKERVFQSVQDFYKRRVAPYLPKEEFDSLSGRFQLFLEASSAEDFDEQYERYKSRINNSIKWKLKLLKLLPISSWRRKIRQQLWKKEIK
>NZ_CP030848.1|WP_149524995.1|1027765_1029013_+|glycosyltransferase
MKIIFIQHNSFLNGNGGSEKMCTFLANSFSEKGHEVNIAVNQKEGGSPVFPLNSDIKVDNIYNARVDQIELLPIVNYSGKNPIAWLVGKIKKKYTKQVNKNKCRAFPDGYQGVYKHNLKKRSEQWYAYLKAAEPDLIITMSTASLLEITYDNTLDIPIINSVNGRPDYDYEDVFGRRDPLEKNLLKNSYSRLSGIQILLDDYDKFLPDTFKGKVFVIGNPFPEVDTTEHVDHQIEKSQYVISHLGRLDNDCKQQTLAIEAFHRACSENSEWRLDLWGTGADRDMIQQKIAELALGDKVALKGFCTDPIAVLKNADIFLFPSRYEGFPLALGEAMSVGLPAIGLGSCSGVNKLIVDGESGYLVENVEAMAFRLKQLMNNSALRQEMGKRGVELMRAYTPASVLAKWDELINEIVER
>NZ_CP030848.1|WP_149524996.1|1029018_1030200_+|glycosyltransferase
MNKRKILYFMTDNPMRYKAGNTTRCNKMLDYFSSRSDVFDVDFLTLQPWTEEEIEKFKSIYPTIKLDLFRPGSEFSKKDNYTKYFIHEKLPRLIGKKRNAKKLISLVTPFVEKQLLERYADRHYDVLIVSYAYWAELIKLIPATYKINDTHDFLSVQHAPQESNDFAAVGKMFQEELSLLNPFDEVWSYSVEERFIFDQFLNTKVKLVPLSFEDRTAKGEIAKEYDILYVASDNHHNVTSMNWFMEHVLPSLKNRKVTVVGKICDAIPDHSQITKLGLVEDLDKEYSKARITICPMLSGTGVKIKVLESLSFGIPVVTTMRGVDGLLNKTNNGCLISDNPTEFVDNIELLLNDDKAYQMHRADAVRYFQQHHHPSKELDFLNSSLLQSDSSRR
>NZ_CP030848.1|WP_149524997.1|1030222_1031038_-|glycosyltransferase
MSISSDKPKTVSILISTYNWPEALERCVQTVWAQDRLPDEILIADDGSKEPTKRLIERLKQESPVPIVHVWHPDEGFRLSVIRNKAIAIASSEYIIQIDGDILLDPHFIKDHLSLVEPNYFLCGSRVWVSKEQSQELLEQKSTIKVQRHKFPLPFILNSLRSGILSRFLADRYKKNKPRILRGCNMSFWKKDLLAVNGYNEAIQGWGSEDAELAFRLMNTGVKKRFLKFAAVAYHLYHKENNKENLPENDKILEDTINTKKVWAKEGIVKQ

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Crispr_ID: NZ_CP030848_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_2

1159920-1160035

Orphan

Consensus_repeat	Method
GTTAGTACTTAGTATAAAGACCTATGGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_2

>merge|NZ_CP030848|2|1159920-1160035|CRISPRCasFinder
GTTAGTACTTAGTATAAAGACCTATGGCGTAATATCCCGCTCATCCTTACATCCTTTCTTTCCTGGTTCAGAAAAAGTATTTAGTAGTTAGTACTTAGTATAAAGACCGATGGCGT

>NZ_CP030848|2|2|1159920-1160035|CRISPRCasFinder
GTTAGTACTTAGTATAAAGACCTATGGCGT	AATATCCCGCTCATCCTTACATCCTTTCTTTCCTGGTTCAGAAAAAGTATTTAGTA
GTTAGTACTTAGTATAAAGACCGATGGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525098.1\|1165925_1167170_+\|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl\|CDD\|234638
NZ_CP030848.1\|WP_149525099.1\|1167179_1168553_+\|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	unknown	unknown	gnl\|CDD\|223842
NZ_CP030848.1\|WP_149525086.1\|1145477_1146479_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl\|CDD\|236585
NZ_CP030848.1\|WP_149525095.1\|1161907_1162318_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525100.1\|1168570_1169770_+\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|274232
NZ_CP030848.1\|WP_149525089.1\|1152843_1154679_+\|DUF3520-domain-containing-protein	unknown	unknown	gnl\|CDD\|378796
NZ_CP030848.1\|WP_149525084.1\|1143288_1144242_-\|transketolase-family-protein	unknown	unknown	gnl\|CDD\|226467
NZ_CP030848.1\|WP_149525085.1\|1144297_1145146_-\|transketolase	unknown	unknown	gnl\|CDD\|238970
NZ_CP030848.1\|WP_149525097.1\|1164462_1165920_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|234660
NZ_CP030848.1\|WP_149525096.1\|1162334_1164461_+\|PASTA-domain-containing-protein	unknown	unknown	gnl\|CDD\|223839
NZ_CP030848.1\|WP_149525094.1\|1160976_1161888_+\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|234597
NZ_CP030848.1\|WP_149525092.1\|1158599_1159592_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149525091.1\|1156273_1158028_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP030848.1\|WP_149525088.1\|1150961_1152239_-\|TonB-family-protein	unknown	unknown	gnl\|CDD\|372685
NZ_CP030848.1\|WP_149525093.1\|1160510_1160984_+\|division/cell-wall-cluster-transcriptional-repressor-MraZ	unknown	unknown	gnl\|CDD\|234728
NZ_CP030848.1\|WP_149525102.1\|1170877_1172233_+\|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl\|CDD\|234757
NZ_CP030848.1\|WP_149527645.1\|1152189_1152648_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP030848.1\|WP_149525090.1\|1154776_1156162_-\|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl\|CDD\|224062
NZ_CP030848.1\|WP_149525101.1\|1169774_1170875_+\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|234825
NZ_CP030848.1\|WP_149525087.1\|1146544_1150927_+\|translocation/assembly-module-TamB	unknown	unknown	gnl\|CDD\|367909

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525098.1\|1165925_1167170_+\|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl\|CDD\|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	2.48884e-163
NZ_CP030848.1\|WP_149525099.1\|1167179_1168553_+\|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	gnl\|CDD\|223842	COG0771, MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane].	2.37435e-138
NZ_CP030848.1\|WP_149525086.1\|1145477_1146479_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl\|CDD\|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
NZ_CP030848.1\|WP_149525100.1\|1168570_1169770_+\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|274232	TIGR02614, Putative_lipid_II_flippase_FtsW, cell division protein FtsW. This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	3.21773e-76
NZ_CP030848.1\|WP_149525089.1\|1152843_1154679_+\|DUF3520-domain-containing-protein	gnl\|CDD\|378796	pfam12034, DUF3520, Domain of unknown function (DUF3520). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 180 amino acids in length. This domain is found associated with pfam00092.	2.34358e-99
NZ_CP030848.1\|WP_149525084.1\|1143288_1144242_-\|transketolase-family-protein	gnl\|CDD\|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	7.9046e-130
NZ_CP030848.1\|WP_149525085.1\|1144297_1145146_-\|transketolase	gnl\|CDD\|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	3.17119e-124
NZ_CP030848.1\|WP_149525097.1\|1164462_1165920_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NZ_CP030848.1\|WP_149525096.1\|1162334_1164461_+\|PASTA-domain-containing-protein	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	7.29646e-106
NZ_CP030848.1\|WP_149525094.1\|1160976_1161888_+\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	5.2776e-156
NZ_CP030848.1\|WP_149525092.1\|1158599_1159592_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	4.96444e-16
NZ_CP030848.1\|WP_149525091.1\|1156273_1158028_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP030848.1\|WP_149525088.1\|1150961_1152239_-\|TonB-family-protein	gnl\|CDD\|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	4.84085e-10
NZ_CP030848.1\|WP_149525093.1\|1160510_1160984_+\|division/cell-wall-cluster-transcriptional-repressor-MraZ	gnl\|CDD\|234728	PRK00326, PRK00326, transcriptional regulator MraZ.	1.84318e-43
NZ_CP030848.1\|WP_149525102.1\|1170877_1172233_+\|UDP-N-acetylmuramate--L-alanine-ligase	gnl\|CDD\|234757	PRK00421, murC, UDP-N-acetylmuramate--L-alanine ligase; Provisional.	0
NZ_CP030848.1\|WP_149527645.1\|1152189_1152648_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.18581e-19
NZ_CP030848.1\|WP_149525090.1\|1154776_1156162_-\|iron-sulfur-cluster-binding-protein	gnl\|CDD\|224062	COG1139, COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion].	2.00813e-173
NZ_CP030848.1\|WP_149525101.1\|1169774_1170875_+\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|234825	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional.	6.40506e-134
NZ_CP030848.1\|WP_149525087.1\|1146544_1150927_+\|translocation/assembly-module-TamB	gnl\|CDD\|367909	pfam04357, TamB, TamB, inner membrane protein subunit of TAM complex. TamB is an integral inner membrane protein that forms a complex - the translocation and assembly module or TAM - with the outer membrane protein, TamA. TAM is responsible for the efficient secretion of the adhesin protein Ag43 in E.coli K-12.	2.98545e-32

>NZ_CP030848.1|WP_149525092.1|1158599_1159592_+|transposase
MKKDRITLGVDVSKKTLDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLEPSGKLNSTIFDLKQLISFRKRLVREMAGYKASSSERKAMYGKDAGKVILKVSKTMIDVYKKEIYRVEREILQLIESDESLNRNYQILKSVKGIGPVNAWMTIVYTENFKAFTGPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYAQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149525091.1|1156273_1158028_-|aspartate--tRNA-ligase
MHRTHTCGELRIEDIGKTVTLSGWVQKSRDLGGMTFIDVRDRYGITQLTFNSDDDESLRSRARELGREFVIKATGTVIERSSKNSKIPTGEIEIKVSNLEILNESKLPPFTIEDETDGGDDIRMKYRYLDIRRNPVKNSLLFRHKVTQEVRNYLSNLDFCEVETPYLIKSTPEGARDFIVPSRMNPGQFYALPQSPQTFKQLLMVGGMDKYFQIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDILNIFEGMTRHLLKTIHGIKLDQFPRMTFDEAMRTYGNDKPDIRFGMKFGELNAVAQHKEFAIFNNAELVVGIAVPEAASYTRKQIDELIDWVKRPQVGASGMVYAKYEADGSIKSSVDKFYDQADLLKWAEATGAKPGDLILVLSGPANKTRAQLSALRMELGNRLGLRKPDEFAPLWVIDFPLLEWDEESGRYHAMHHPFTSPKLEDMPLLDTDPGKVRANAYDLVLNGNEIGGGSIRIHDKEMQALMFKHLGFTEEQAQDQFGFLMNAFQYGAPPHGGLAFGLDRLTAILGGQETIRDFIAFPKNNSGRDVMIDAPATIALEQLDELNIALKPLTK
>NZ_CP030848.1|WP_149525090.1|1154776_1156162_-|iron-sulfur-cluster-binding-protein
MAASVADKFLQDSKTKSFDLRHRQIINTNIDKYNVAFERGKSKFHDLENSKQKANLIKWKVMENLDRYLLDFESNFTKNGGHVIWANDAEEARQEIAKIIEQHNAKSVIKSKSMATEEIELNHFLAKKNIETIESDLGEFIIQLLDQKPYHFVTPAMHLSLEDIAKLFHERFETPLEATAEELTMKAREILREKYTTADIGITGANFLVADSGSIAITENEGNARLTTSFPKVHIAVVGIEKVIPNMGDLDLFWPLLASHGTGQNLTVYNTLLSGPRKAAEADGPEEMYVILLDNGRTNVLEQKDQRQGLYCIRCGACLNVCPIYQNIGGHTYETTYQGPIGSLISPHLNGMKEFKHLSYASSLCGKCTEVCPVGIDIQKMLLLNRRDSVQENFTTGSEKKAWGLFTWAIQKRKIIDFFGGKTKNFFVRNFFKKAWGESRELPKIAEKSFSQQYKEMQKKK
>NZ_CP030848.1|WP_149525089.1|1152843_1154679_+|DUF3520-domain-containing-protein
MKSILSILMVFFALVGGAHAQEKVITGQVTDRESNLPLQGVEVSVLGKYKSTRTGQDGKYSIKAVDGDKLLFSFIAYQKQTVKVGKKTVINIALQPENQVLEEVVVTGVKGVAKMNDVSYQVASSSPGIMISRMPVSMDTESYKNIDENAFKSPLKDPLSTFAADVDAASYSNVRRMINAGNLPDRDAVRVEEMINYFQYDLKAPTNGDPVRIYTELGVSPWNKEHQLIRIALKAKDIPSAQLPASNFVFLIDVSGSMYAANKLPLVKSSLKLLVDQLRDQDRVAIVTYAGSAGVKLESTSGTQKMKIKEAIDELVSGGSTAGGAGIRKAYDIARQNFMKNGNNRIILASDGDFNVGASSDDDMEKLISKERESGVHLTVLGFGMGNLKDSKMELLANKGHGNYAYIDNISEARKAMVTEFGGTLFTVAKDVKIQVEFNPAYVQAYRLVGYENRLLAAEDFNNDAKLGGDMGVGHSVTAIYEIVPVGVKSSIIGTVDPLKYQDNKNAAQGTLNGELATVKFRYKEPESDKSKLQQVIVSNKMASIDQMSEDFRFAAAVAELGMLLRNSDYKQEASYKNLVARAKAAKGKDDEGYRAEFIRMAENAAVLDKR
>NZ_CP030848.1|WP_149527645.1|1152189_1152648_-|sigma-70-family-RNA-polymerase-sigma-factor
MVFYVCLRYFKEPERSRDAVMQIFEELIDKVKKQSIQDFPRWLYVVSKNHCLMALRSAKSKPEIVTNDFVEFAANLHQEENYKEREEQLSQLESCIDRLIEKQQQSIRLFFIEEKCYKEVAEITGYSMNDVKSAIQNGKRNLKICMERAQHE
>NZ_CP030848.1|WP_149525088.1|1150961_1152239_-|TonB-family-protein
MEKGTSKFVWKGHNMSNHFDIAYLRRYVNGELSSSEMYAIEKASHQNEMLMDIIMGLEEEQRLKSSLNPTELHAAIYERTHPGKIKTLLPYKALGIAASLLLVLGIGTIWYLNRPQDETELAMAPADIAETAPTDTTLNSIELDSFEEDSTSNLIAAAPELNESKAQQSTARTAERASSREETRKKDLVISPDLFIDTVQVISGKMLAKRSPANNPNVISLQGKVSGISVAPQAEMSARVGSPQDYKRIITGEVIDQDSGYPIPQATVRNVKTNEVVMTDSSGSFVMPSAIESTELEILSIGYQSARILASNQQTIRLAPDYATLDEVVVIDAGKNQSKIKSEPLIGWKAYKKYINDHSKESLFGKGNVTLVFEINNFGRPTNIIVLKSANPSLDQQAIQIIKNGPDWKKGNDGKRIEVKIEFRQ
>NZ_CP030848.1|WP_149525087.1|1146544_1150927_+|translocation/assembly-module-TamB
MLGLIAVLCLVVLSLQFASVQTFVTKRVANYLSDELNAKVELKHIYFRPFDQLTLTEFKLSDQQGKPMLSAEKLHADLMLRHFFQNKIVIEDLALHKAYVDFQVYKDSSNFKFLIDYFAPKKKPEGKKKKPLELQLHNLTLVDNHIKILNHQQKHHNRGVDFSDIELQHLNVNLANIKFDSISLKTDIKELSLQEKSGFQIKRLLAKAYISNTSMEFDQLDLETNRSKVGRYLKFSYKKFADFGDFIKKVHIEGTMDDVYVDSRDIEYFAPTMNRVQFTASVPQATVEGTVNNIRSQNAYIKTGKETLLRGDFSIKGLPNMDKTIFDFEASDLQTSAKDLELLIPKLANRAKFSLPEQLHQFGLIKFEGTFNGLYNLFDIKGDFDTQLGALNTDSKIDIRKEITYQGHLASKSFQLGELIGSKSIKNTAFAFDFDGQSLDFNKMKLQLEGGLRNFQFGNYSYDSVEVSGLLDQKLIDVTGFIQDPNAQLAYDAKVDFQSAEASYDVSADVELINLKKMGFVEKDSIVIFNSQINTHLTGNNLNNLNGDVIAEQINMQTTKGDFTVNDLFFSAEGTQMDRLLTLRSNVLDAEMKGVIDLNTLIPYFKALAMRYAPAIGLTVEPYNPQIFDLQLNVKSFEPVSAFLDPTLILDDGASLEAHFSSEDFTAEFTAFSPFVRYQGINVQNIHIRENADEEAFSLDVTADKLFLSDSIFVTDIEINNILSNDSLLFSINGAKETDLNYLRLNGDIHFAHNKPAYIHFNKSSIIVNKEPWTLNTDAEMRVSKGKFYLTNLIASQGQQKVAFNGVLSNEDDKLEVNFSKFNLNALEVVLKPLGIRLDGELNGDIELHSAFKKPYLSANVQTSPLVYNQIPIGQLRLLADFDPETKQANLDLQLLDDLNKGLKLNGTYQIAGVDQELNLKGSLNQMELILFQPFVRTLTSQLQGKMNAEIQIGGTLKNPEFNAISKIEYASFNVNYLKTSYNISNQTVLLDKNNILLNQLAFNDSKGHQAVANGIVNLNKLSNPYIDVDVVTNNTMILNTTYKDNNLYFGTAYATGTFKFKGATSAIDINIKARSEDNTSITIPFNSAMTVTDSDFIYFVSNDSSKNKQQESKYLLKGMTMNMDIEFTPTAEVNLQTDLGSLKGNGTGEITLKVSSLGDFEMFGDYTVNSGKFHFTAQDFFNKFFDIKQGGTIRWTGSPSGATINMTAIYQQRTSISPLYNAAGRSGQDERVMAQADMNIKGTLSQPDVSFDLNFPQTPYVKDELQAYLSDANNVNQQALSLIVRRSFTASSNNELGREVNNTLLSAGTEIAFNQLNNILAQSLKIDFLDFNIRSLNDASASFRFFNDRLVLTGGIVDRRNVQTTDLTFFSNKVATDAELTFKLRRDGNLMFRAYNRLNTRNILFTPTDDYINAVGLIYRQEFNTLGEFWRKLWNWSGTRSDLPIKPIPTLDTTKKEIK
>NZ_CP030848.1|WP_149525086.1|1145477_1146479_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MAIILGIESSCDETSASICIDGEIRSNIIASQAIHAKYGGVVPELASRAHQQNIIPTVDQAIIQAKISKKDIDAVSFTRGPGLLGSLLVGTSFAKSFALAMDIPLIEVNHMQAHILAHYIDNPKPSFPFLCLTVSGGHTQIVLVKDYFEMELLGETLDDAAGEAFDKTAKILNLPYPGGPLIDKHAKNGAPTAFKLPEPQIPELNFSFSGLKTAILYLVQAEIKKNPNFLEERMDDLCASVQDRIVSILLNKLKKAAKQTGVKDIAIAGGVSANSGLRSSLLAMGEKYKWNVFIPKFEYCTDNAAMIAIAGYHKFLEQDFVGQDISPLARMHV
>NZ_CP030848.1|WP_149525085.1|1144297_1145146_-|transketolase
MSADINKLEQTASQVRRDIVRMVHACQSGHPGGSLGCTDYFVALYFHAMKHDPSFNMDGIGEDLFFLSNGHISPVFYSTLARAGYFPVSELATFRKIDSRLQGHPTTHEHLPGIRVASGSLGQGLSVAIGAAQAKKLNKDNSLVYVLMGDGELQEGQVWEAAMYAPHNKMDNVIAAVDYNNAQIDGSTETVLSLGNLRAKWEAFGWDVLEVEKGNDMASVVAGLDEAKSRTGKGKPVIILLHTEMGNGVDFMMGSHKWHGVAPNDEQLASALNQIPATIGDY
>NZ_CP030848.1|WP_149525084.1|1143288_1144242_-|transketolase-family-protein
MKKYTYTESKDTRSGFGAGLLEAGQQNENVVALCADLIGSLKMNDFIKAYPERFFQIGIAEANMMGIAAGLTIGGKIPFTGTFANFSTGRVYDQIRQSIAYSGKNVKICASHAGLTLGEDGATHQILEDIGLMKMLPGMTVINPCDYNQTKAATIALVDHEGPAYLRFGRPVVPNFTPADQKFEIGKAVMLNEGTDVTIIATGHLVWEAIQAGEELEKAGINAEIINIHTIKPLDAEAILKSVAKTKCVVTAEEHNRLGGLGDSVAQVLAKELPTPQEYVAVNDSFGESGTPAQLMEKYGLTAADIVKAAKKVISRK
>NZ_CP030848.1|WP_149525093.1|1160510_1160984_+|division/cell-wall-cluster-transcriptional-repressor-MraZ
MNQLIGEFECKLDTKGRMVVPASLKRQLPEAEREGLVVNRGFEKNLVIYTREEWNKKMAQLAKLNQYNAKNRNFIRQFMRGATELSLDSAGRVLLPKGLLEYAGIQADVVLACQFDKIEVWSKAEYDAIMDADMGDDFAALAEDVMGGFDFGGMENE
>NZ_CP030848.1|WP_149525094.1|1160976_1161888_+|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MSNEIGYHVPVMLQECIDALAIKPDGIYVDVTFGGGGHSKEILKHLGPKGRLIAFDQDPDAVKNALDDPRFTLIHQNFRFLKNYLRLEGIRAVDGILADLGVSSHQFDDADRGFSIRFDADLDMRMDQVSDLDARKVLSTYAEEDLHRIFGMYGEIINAKTLAKTIVTARLNQEINTVAELKEVIKKLVPKGKEHKYHAQVFQALRIEVNKELEALQEFLEQTVGVLKESGRLVVMSYHSLEDRLVKNFMAKGKFKGEVEKDFFGNEIKPFKVISRKAIVANEEELARNNRARSAKLRIAEKV
>NZ_CP030848.1|WP_149525095.1|1161907_1162318_+|hypothetical-protein
MARNTIKNKELSEEVQEEMSDALEEKVEETEDFLKSIFSQKKLSTYLVAKNLPFVAFLALLGLLYISNRHLAENTVRRIDRLGKEVKELSWDYKSLNAELMKLTTQTEIAKRADTLGLKERTEPPIKLQVVKEVKQ
>NZ_CP030848.1|WP_149525096.1|1162334_1164461_+|PASTA-domain-containing-protein
MNIRKSILIRVYLAFGLMVFGALLVFGKLLHLQYVDGDRWRAIADSLTIRERVVEAARGNIYSNDGSLLATSVPEYDIRFDAMAIPAEENDVFNARVDSLAIQLSKFFGDKSSRQYLGQLKEARAKKQRYLLIKRAVSHQQLKALKQFPLLKGFKENKKRYSSSLIAVRENKRILPFTNLAARTIGYKNTKGDTVRVGLEGAYGDYIEGRSGVQLMQRIAGGVWIPVNREMEVAPTDGSDIIATIDVNMQDMAQRALEKQLIQSNADNGCVILMEVNTGEVRAIANFTRDTEGVYREKFNYAIAQGADPGSTFKIASYLVALDDGVIDTNTIVDIGNGTYKVPSHTIRDSHPPKKSKVTAKEAFEESSNVGVAKLINQHYGSNPAKYTGKLHKWGLNDPLGLQIPGEGKPWVKMPDSRSWSKLSLVQMAYGYELKLTPLQTLTLVNGVANNGRLLAPLFVKEIQHLGNTVQKFDARVINKQMASEDAIRKMQKMMEGVMVEGTGKRLRSPLYSSAGKTGTAQMADGSRGYGARRYQSSFVGYFPAENPKYSMIVVIRNPRNGYYGGSVAGPVFRELADMVYANDLSLHSTLDKRQVNFKGAKVPYTLRGSKDATAKVYQMLGIQSVNWNAIVQSDSGANSTNALPFTSAEFKEGVVPDVKGMGLVDAIFAMENAGFKTTVRGKGKVFNQSLAAGQRLKSGTKVLIELH
>NZ_CP030848.1|WP_149525097.1|1164462_1165920_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MLLKELLHAIPVKDYQGTLDAEVTSVCLDSRKAQAGSAFVAVRGHQTDGHLFIAKAVELGASVVLLEEYPAEISEGVTYILVDDSSFALGVFAANFYGNPSKDLKLVGVTGTNGKTTVATLLFNLFTKLGYHVGLLSTVQNQIGDRIVPATHTTPDPISLNALLREMLDDGCDYCFMEVSSHAVVQQRIAGLRFAGGIFTNITHDHLDFHGTFANYIKAKKKFFDDLDRYAFALTNIDDKNGVVMLQNTFAHRKTYGLHQMADFKAKILESHLDGMLLQIDSQELWVKLVGHFNAYNLLAVYGAAILLEQETMKVLTALSEISGAEGRFETVRSNNGIVAIVDYAHTPDAVENVLETILDLRKQGQQVLTVLGCGGDRDKTKRPEMAEVAARLSDKVILTSDNPRSEDPVQIIRDMEAGLPAEKKKNVFSITDRREAIRAAVHLAQPGDVILVAGKGHEKYQEIKGVKNHFDDREELENIFNEIN
>NZ_CP030848.1|WP_149525098.1|1165925_1167170_+|phospho-N-acetylmuramoyl-pentapeptide--transferase
MLYYLFTWLNEHVHIPGAGLFQYISFRTAMAVIVSLIITTVFGSRLIRLLHQKQVGETIRDLGLEGEKKKQGTPTMGGLIIIAGILIPTLLFAKLDNIYVILMIITTVWMGAIGFLDDYIKVFRKNKEGLAGRFKVIGQIGLGVLIAITMYFHPDIVVRQQVTNPTSSKPVEVVINPSTGEKIYAENVKSTKTNIPFYKNNEFDYAKVLDFLGVNNPWATFMVFLVVVVFIVTAVSNGANITDGIDGLATGTSAIMGITLAILAYVSGNIIFSDYLNIMYIPNSSELVIFAGAFIGACTGFLWYNAYPAQVFMGDTGSLAIGGIIAAFAILIRKELLIPVLCGVFLIENLSVILQVSYFKFTKKKYGEGRRIFLMSPLHHHYQKKGYHESKIVTRFVILSIILAILTIVTLKVR
>NZ_CP030848.1|WP_149525099.1|1167179_1168553_+|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase
MSNIAHTYYPQSGRLVILGAGESGVGAAILGKDKGFDVFVSDMGQIADSYKQTLEKEQISFEEGKHSEELILNADLVVKSPGIPEKAPLIKQLRSLNKPLISEIEFAAQYTDAKLYCITGSNGKTTTTMLTYSLLKEGGVDVGLAGNIGNSFALQVARDPHACYVLEISSFMLDDMYHFRADVAVILNITPDHLDRYEYKMENYVASKFRMLQNQRETDYFIYCLDDPETVAALDKHPTKAIHLPFTQEQALTQGAFVDADNTLNILVPNREVFTMNIEELSLQGKHNVYNNSAAGLIAKVQELRNQSMKESMGSFVNIEHRLEHVASVGGVNYINDSKATNVNSVWYALESFSTDIVLIMGGVDKGNDYDMLRDLVKSKVKAIICIGKDTGRIHEAFEDDTEVIVNSASMSDAVQIASHLAKKGDTVLLSPACASFDWFKNYEERGDKFKEAVMAL
>NZ_CP030848.1|WP_149525100.1|1168570_1169770_+|FtsW/RodA/SpoVE-family-cell-cycle-protein
MEYIFSKLKGDKWIWIIVILLSIWSLLAVYSSVGTLAYKEGKGTEMYLFKHLFIVVAGLGLMYLSHKLDYRYYAGISKLLMLITIPLLLYTLLFGSKVNEASRWLTIPIINQTFQTSDLAKLALITFLARMLSRKQEEIKDVKKSFIPIMGAVCAVFVLIALANLSTALMLFGVSVLLLMIGRIDFKQIAVVCLGGAVLLTLVMLLGPRRGTYISRIQGFFQTEEVHDSKGSFQEDKNFQANNAKIAIATGEMFGKGVGNSVQRNVLPHPYSDFIFAIIIEEYGTIGGAVLLFLYIALMYRCIRIVTLSPRAFGAFLAAGLGFSLTIQALANMAVAVGLGPVTGVPLPLVSMGGTSILFTSVALGIILSVSRNIEELKHKEELDVVKKPAARKVVVGTI
>NZ_CP030848.1|WP_149525101.1|1169774_1170875_+|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase
MAHKVIISGGGTGGHIFPAIAIANALKQLAPDTEILFVGAEGKMEMERVPAAGYEIVGLDIVGINRQSLLKNSALPFKMLKSLLKARSVLKQFKAEVAIGVGGYASGPLLMMANMMGLPTIIQEQNSYAGVTNKKLGAKAKKICVAYEGMDRFFPAERILLTGNPIRKSSVAIENKREEAINAFALDMNKKTILVTGGSLGALTLNDCIKAGIPQFVEAGVQVIWQCGGYYYEKLKEELGDSLPEEIKLMAFVDRMDYAYAAADVIVGRAGAGTISELCVVGKPVVLVPSPNVSDDHQTKNAMALVSKDAAIMVKDNEAREVLVRKLLSLLKDEPKMQGLGDAINKLALADADVVIAQEVLNLIRK
>NZ_CP030848.1|WP_149525102.1|1170877_1172233_+|UDP-N-acetylmuramate--L-alanine-ligase
MNIDKIKRVYLLGIGGIGMSGLARYFSRLGCEVAGYDRTSTELTRTLEEEGMPIIYTDDVAAVPASFESAGEDTLIIFTPAIPADLALKSHFIKAGHELYKRSQVLGFISASRFTIAVAGTHGKTTTSTMVAHILKDSGYDCSAFLGGISTNYQNNVLFGDNNVVVVEADEYDRSFLTLHPNIAIVTSADADHLDIYGEASKLQESFQMFLDRVVEDGQKIVRKGLPFAADINYAREEVCDAYAENVVVKDGEFYFDYHSEDLTIKDIHLGIPGLHNVENAVAAITVAKLLGIAAPKIVHALSTFAGVKRRFEYIFKSPEHIYIDDYAHHPEELRAFLTSMKKLYPNKKLTVVFQPHLFTRTRDFVDGFAEVLALADELLLMEIYPARELPIAGVDSQWLLEKIRLENKRLVSPEEVLAIVKSESPELVVTVGAGDIDKLVKPIKEVLTNA

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Crispr_ID: NZ_CP030848_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_3

1502059-1502145

Orphan

Consensus_repeat	Method
TGAACCAGGAAAGGAAGGATTTAAGGATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_3

>merge|NZ_CP030848|3|1502059-1502145|CRISPRCasFinder
TGAACCAGGAAAGGAAGGATTTAAGGATTCGCGGGATGTTTCGTTTGGATGTTTGTTTTGAACCAGGAAAGGAAGGATTTAAGGATT

>NZ_CP030848|3|3|1502059-1502145|CRISPRCasFinder
TGAACCAGGAAAGGAAGGATTTAAGGATT	CGCGGGATGTTTCGTTTGGATGTTTGTTT
TGAACCAGGAAAGGAAGGATTTAAGGATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525363.1\|1502472_1503381_-\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525355.1\|1488977_1489637_-\|fructose-6-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234947
NZ_CP030848.1\|WP_149525369.1\|1507481_1508108_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NZ_CP030848.1\|WP_149525365.1\|1504012_1504798_-\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|376667
NZ_CP030848.1\|WP_149525370.1\|1508126_1508711_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274376
NZ_CP030848.1\|WP_149525372.1\|1509735_1511427_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|373012
NZ_CP030848.1\|WP_149525371.1\|1508882_1509716_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525360.1\|1493697_1496019_-\|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|227116
NZ_CP030848.1\|WP_149525358.1\|1492153_1492606_-\|clan-AA-aspartic-protease	unknown	unknown	gnl\|CDD\|133150
NZ_CP030848.1\|WP_149525362.1\|1501473_1501899_+\|Dabb-family-protein	unknown	unknown	gnl\|CDD\|214884
NZ_CP030848.1\|WP_149525366.1\|1504988_1505537_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|377230
NZ_CP030848.1\|WP_149525364.1\|1503550_1503859_-\|DUF4342-domain-containing-protein	unknown	unknown	gnl\|CDD\|379521
NZ_CP030848.1\|WP_149525354.1\|1488432_1488891_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_CP030848.1\|WP_149525353.1\|1485748_1487878_-\|ribonuclease-R	unknown	unknown	gnl\|CDD\|273947
NZ_CP030848.1\|WP_149525367.1\|1505543_1505957_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|377230
NZ_CP030848.1\|WP_149525361.1\|1495984_1501252_-\|translocation/assembly-module-TamB	unknown	unknown	gnl\|CDD\|367909
NZ_CP030848.1\|WP_149525357.1\|1490957_1492187_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP030848.1\|WP_149525368.1\|1506094_1507471_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NZ_CP030848.1\|WP_149525359.1\|1492633_1493578_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|180477
NZ_CP030848.1\|WP_149525356.1\|1489921_1490830_+\|transposase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525370.1\|1508126_1508711_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274376	TIGR02985, Sig70_bacteroi1, RNA polymerase sigma-70 factor, Bacteroides expansion family 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.	2.61967e-30
NZ_CP030848.1\|WP_149525355.1\|1488977_1489637_-\|fructose-6-phosphate-aldolase	gnl\|CDD\|234947	PRK01362, PRK01362, fructose-6-phosphate aldolase.	3.41694e-145
NZ_CP030848.1\|WP_149525369.1\|1507481_1508108_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	4.23364e-18
NZ_CP030848.1\|WP_149525365.1\|1504012_1504798_-\|TSUP-family-transporter	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.30475e-27
NZ_CP030848.1\|WP_149525372.1\|1509735_1511427_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|373012	pfam14322, SusD-like_3, Starch-binding associating with outer membrane. SusD is a secreted polysaccharide-binding protein with an N-terminal lipid moiety that allows it to associate with the outer membrane. SusD probably mediates xyloglucan-binding prior to xyloglucan transport in the periplasm for degradation. This domain is found N-terminal to pfam07980.	2.28107e-28
NZ_CP030848.1\|WP_149525360.1\|1493697_1496019_-\|BamA/TamA-family-outer-membrane-protein	gnl\|CDD\|227116	COG4775, COG4775, Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane].	5.8143e-20
NZ_CP030848.1\|WP_149525358.1\|1492153_1492606_-\|clan-AA-aspartic-protease	gnl\|CDD\|133150	cd05483, retropepsin_like_bacteria, Bacterial aspartate proteases, retropepsin-like protease family. This family of bacteria aspartate proteases is a subfamily of retropepsin-like protease family, which includes enzymes from retrovirus and retrotransposons. While fungal and mammalian pepsin-like aspartate proteases are bilobal proteins with structurally related N- and C-termini, this family of bacteria aspartate proteases is half as long as their fungal and mammalian counterparts. The monomers are structurally related to one lobe of the pepsin molecule and function as homodimers. The active site aspartate occurs within a motif (Asp-Thr/Ser-Gly), as it does in pepsin. In aspartate peptidases, Asp residues are ligands of an activated water molecule in all examples where catalytic residues have been identified. This group of aspartate proteases is classified by MEROPS as the peptidase family A2 (retropepsin family, clan AA), subfamily A2A.	1.08987e-09
NZ_CP030848.1\|WP_149525362.1\|1501473_1501899_+\|Dabb-family-protein	gnl\|CDD\|214884	smart00886, Dabb, Stress responsive A/B Barrel Domain. The function of this domain is unknown, but it is upregulated in response to salt stress in Populus balsamifera (balsam poplar). It is also found at the C-terminus of a fructose 1,6-bisphosphate aldolase from Hydrogenophilus thermoluteolus.It is found in the pA01 plasmid, which encodes genes for molybdopterin uptake and degradation of plant alkaloid nicotine. The structure of one has been solved and the domain forms an alpha-beta barrel dimer. Although there is a clear duplication within the domain it is not obviously detectable in the sequence.	1.50568e-16
NZ_CP030848.1\|WP_149525366.1\|1504988_1505537_+\|YeeE/YedE-family-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	3.17685e-09
NZ_CP030848.1\|WP_149525364.1\|1503550_1503859_-\|DUF4342-domain-containing-protein	gnl\|CDD\|379521	pfam14242, DUF4342, Domain of unknown function (DUF4342). This family of proteins is found in bacteria. Proteins in this family are typically between 97 and 206 amino acids in length. There is a single completely conserved residue P that may be functionally important.	3.92844e-20
NZ_CP030848.1\|WP_149525354.1\|1488432_1488891_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	1.12839e-20
NZ_CP030848.1\|WP_149525353.1\|1485748_1487878_-\|ribonuclease-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
NZ_CP030848.1\|WP_149525367.1\|1505543_1505957_+\|YeeE/YedE-family-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	0.000114579
NZ_CP030848.1\|WP_149525361.1\|1495984_1501252_-\|translocation/assembly-module-TamB	gnl\|CDD\|367909	pfam04357, TamB, TamB, inner membrane protein subunit of TAM complex. TamB is an integral inner membrane protein that forms a complex - the translocation and assembly module or TAM - with the outer membrane protein, TamA. TAM is responsible for the efficient secretion of the adhesin protein Ag43 in E.coli K-12.	1.76485e-48
NZ_CP030848.1\|WP_149525368.1\|1506094_1507471_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.39638e-82
NZ_CP030848.1\|WP_149525359.1\|1492633_1493578_-\|malate-dehydrogenase	gnl\|CDD\|180477	PRK06223, PRK06223, malate dehydrogenase; Reviewed.	1.44831e-144
NZ_CP030848.1\|WP_149525357.1\|1490957_1492187_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.98522e-68

>NZ_CP030848.1|WP_149525362.1|1501473_1501899_+|Dabb-family-protein
MKRKAFIGSLLVGAAAGSVLNSCAEPKTNTTNMDTSLSKETIVHSVYFWLKEGITAEEEKDFLNFFTTLSKIEGIKELKYGKPAPTTPRPVVDNSFSYLLLITFNNMDEINVYENHPDHLAAIEIYKKYWTKVEVKDAILM
>NZ_CP030848.1|WP_149525361.1|1495984_1501252_-|translocation/assembly-module-TamB
MNKFGRIAIKTFLWIIGSIIALLLLVIFLVRLPAVQNYIVGKVTNYLENKIGTQVDIGHINITFPKKLVLENVFFADQSKDTLIAGEQLLVDINMFKLLKNTVEIEELELKGITAKINRKLPDSAFNFSYIVNAFATEKESTATADSTSALTFDIDKVLFERIKFVYKDDVIGTSADLYLNHFDTRIKTFDLTKNMTFDMPKINIDGLQARIKQWQVTAEEEAPDASDFGITDPSVEASSLLPNLATEVLGLKNIYIQYDDEASNINTKFTIKELIANVDQIDLNKELVKLKEVKLTDSESEVFLGKSAPKAETESADSSSVNWIVSVDKIGIAKTNVWFRDDNQPRMKGLDYFNLKLTDLAGAMDNVYYSADSISGNLANLAVKDHSGFELRQLKGDFVYTNTGAIVKDFLIETPNSIIRDNIKVSYPSLAAVSENPSNVTIEATLKKTQIDMRDIRYLAPDLEKEETMKPLMDKKFYIDGKVLGKLNDLRIPKVEFKTLNNTHLIASAHIKGLPDMNKMYLDLDIRKMTTSRADLNRLIAPSLLPDSIQLPRNISLVGTFKGGMSGFDTDLKLVTEQGNATVNGTLNMGRDTTYNAFVSVDNFNLGEFLKQDSVLGFIAAQAQVKGTGLNPKTMVADATGTLKRFDAMGYGYRDIDFDFTADRGDISGNLHSPDPNVQLNASIQANMQGQYPRLYAEMMIDSINLKNLKLMDENLRYHGKIIADFETFDLDHLNGSLQIANSSIAYNDDRYVLDTVALTAQADTNRNILILSSEFMNAHLAGKYKLTELGASVQDIIRTYYNPSNDHTPLVYSPQQFEFSARLNNARIIREFFPALEELQDITLDGTFNSEDKALMAKLLAPKIMYDGTEVENIGMDIITVDSTMYYNALIEHIKVSGVELRNTVLSGNVVENKVDLGLWIKDKEDKEQYHLGANMSVDANNYNFSLKEDGLMLNYEKWGINPNNLLSFGSAGIRANDFHLSKDGQEMIIQSKDSTMNSPIDLTFNNFRIETITRMLNSENLTLGGGINGTATVSRLEANPVFVSDLNIEKFFFGKDTIGNVMLKVNNIKENTYSADVRITENGNDVQLIGDIIVPAEGDMQIDATLDLKPMTIKTIEAFSMGQLKGSQGDLSGSLRITGTTSAPRINGDLTFNDAIINASMLNSNMKIDNQKIYFNDQGITFRQFNLLDSRNNVARLNGSIRTTTYTDFVFNLNLTTDDFEVMNSTREDNDMFFGKMYITSNLRITGDLNKPRIDGNVKANDRTDFSFIVPNDDPGVTQRDGVVKFVDKSDTARANVFAKLDSMTTATTLSGYDIALNLSTDPDAKFKIILDEGTQDALNIQGIAEINTTIDANDKITMSGTFTVEDGDYTFSFGPISKDFRFQKGSTITWNGDPLDARLDITALYSGKFATLELVQNQIGAESQNLYKQRIPFNVKLILTGELFKPQINFDIDVDENNAVASQDVISKVNIALANIREDPAELNKQVFSLIALGRFMSNNPFESLSGGGPESLARSTVSSFLTSQLNNLASDLIKGVELDFNLNSEEDYLTGSAQTRTDLNVGISKMLFDDRLKITIGSNFEVEGNSRPGEKATNIAGDISLDYQLSKDGRYFARVYRKNQYQATLQGQFVETGIGFIINMSYDRFRELFMSSKAIAAYNTDSRGFRRRFDVERMDTDSVYRDSVRMVIRDSLMTHSPEYRKRIEKEQQEELKKQQEQQDSTRNLPDTSKVTEPKKAAIKNEEEEGESNEK
>NZ_CP030848.1|WP_149525360.1|1493697_1496019_-|BamA/TamA-family-outer-membrane-protein
MKKRKGNPMRNKLILPCFLGLLLSSCNPTKYVAENEKLYKEGDVVIHHDSISEERREGFETFLESSLMPKPNKKFAGIYFKLGMWNMGGGPDSTNNFVRKWLKRNGEEPVLLSDVNREYNQNLLRGKMENLGFFQARVTSDTLIDGKFATVRYDAFPGKIYRINKVQIDIDSTTQIGRSIHDVHNKSVLRPGNNYNLDVILNERERIDNELKYKGYYYFGADNILVEVDSTIGNNKVDMFLTIKPETPEKAKTPQKIGNVYIFPNYRETTGTNRRRIPRGTEKYDGKYYIIDRENRFRKKVLANHIFLEPGKLYHRWEHQQTINHLVNLNAFKFVKNDFVDSPDSANTLDVYYYLTPMQKRALRLELIAKTAAVYNGTEANINWTFKNAFKGFETVTLSVFGGYETQTGGNVNLNSSYIRYGAEVGINWPRLLSPYKWAPGKQYIPRTFLKVGYEFLNRRTAYTLNSFTTNFGYAWKENGQKEHNLTLAEIIYVQPRGISDEYRAQMDTVPTLRHIVDPQFSFGPNYTYTFTNTMEEKKHTFYAKAGLNTSGNILGLIQGADYKEGNIKELFGTPYSQFVKAEADLRHYMKLSASSQLASRIMIGTSYSYGNSRSLPYLKQYFTGGPNGLRAFRARSVGPGSSLPENIGEDNFFADQTGDLKLELNTEYRSKIAGMFHWAAFIDAGNVWLQREDENKPGGKFSKAFLSELAVGGGVGLRVDLDFLIIRTDFAIPFRVPYRDKGDRWVFKYIDIRERDWRRDNLVFNLAIGYPF
>NZ_CP030848.1|WP_149525359.1|1492633_1493578_-|malate-dehydrogenase
MKITVVGAGAVGATTADNLVRRNVAEEIVLLDIKEGFAEGKAQDMMQTAALLGFESHIKGVTNDYQATAGSAVAVITSGIPRKPGMTREELIGTNAGIVKSVVENLIKHSPDIIILIVSNPMDTMTYLALKTSGLPKNRIIGMGGALDSARFKYQISDKLNASANDLNAIVIGGHGDTTMIPLIKHATWNSVKVSSFLTEEEEGEIVKKTMVGGATLTALIGTSAWYAPGAAAAAMVESIVKNQNKLFTASVFLEGEFGQEDINIGVPVIINNKGWDRIVPMELSDKEQELFAASADAVRKMNDVLYDEGILKK
>NZ_CP030848.1|WP_149525358.1|1492153_1492606_-|clan-AA-aspartic-protease
MYKIPFEVIGLQADGFHIITKTTIYDKTFKIVIDTGASKTVLDKQTLLSSGLAEDNFQNTDILSTGLGTNTMESFMLSIPELKLHDWSVKNFTVAVLDLSSINYAYTQIGIAPVIGVLGGDILKAYGAIIDYKKNELRLNQRKLALNRRR
>NZ_CP030848.1|WP_149525357.1|1490957_1492187_+|MFS-transporter
MQLFRSLAYPNFRLHVIGQAISLLGTWMQRIAISWLVYQLTGSVFWLGFVSFISLLPSLVLSPFIGAFVDRHKKYRLVFITQIGLMIQAGLLALLVYLKLESVLYLSILGFIQGVINAFDVLGRQSLLVSLVDDRKDLPNAIALNSSIFNAARMVGPAIGGVLLSTYGELACFTLNFISFIPVIICLMLMKVQEKVIIIPNESAFEGLKHGFEYLKRSPHIMSLIVILTFSSLLVIPYTSLLPAVARELFAGDERTFSWFESAAGLGAMIGAINMARLKSGDNLRYRVLFSALAMGISLALLAYAQYLPAALFFTMGVSFAMMMQNSSINTYIQTHAMPAYRARAMSYYVMAFQGIFPIGSLLTGAIAEIVGIKNTLYIMGACGVLISVGFYIYLRIHIQRRLFKANFR
>NZ_CP030848.1|WP_149525356.1|1489921_1490830_+|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVVEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSKVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149525355.1|1488977_1489637_-|fructose-6-phosphate-aldolase
MKFFIDTANLEQIKEAQDLGVLDGVTTNPSLMAKEGISGEENVINHYKAICAIVDGDVSAEVISTDYEGMIKEGEALAALDSKIVVKVPMIKDGVKAIKYFSKKGIKTNCTLVFSAGQALLAAKAGATYVSPFIGRLDDISVDGLGLIEEIREIYDNYGFQTQILAASVRHSAHILGCAKIGADVMTGPLSAITALLKHPLTDSGLAQFLADHAKAAGK
>NZ_CP030848.1|WP_149525354.1|1488432_1488891_-|transcriptional-repressor
MKVDMDSENLDHQQEEFAQILKANKLKITQPRLRVLDTISTKTAAISQPELEKILGSEIDRVTLYRILASFEEKGILHKVFDLNGTATYALCSTKCTEHHHHDQHVHFICSVCNSVFCLDETNVPKINLPKGFSLQSIAVNAVGLCNQCTEK
>NZ_CP030848.1|WP_149525353.1|1485748_1487878_-|ribonuclease-R
MKSKKENPYKEVLTQLIVDVFEKSGNTALNYKQVAAKLNVKDSDAKVAIADILNDGTRAGQFEQPERGKFKLRQLNVYITGKVDMTADGSAYIVPEDELENDIYVAPRKLRQALHGDRVKVHVYERKKGRKREGEVVEILERAKTDFTGTIDMSNSYAFFLPDDRKMLHDIFIPLDNLNGAKDGEKVLVSIIEWPKNAKNPIGRVKHVLGKKGENNTEMNAILADFGFPLEFPKEVEKEANAIPEDITAEEIAKRRDFRSTTTFTIDPADAKDFDDAISYQVLENGNYEIGVHIADVSHYVIPDTALDKEAFERGTSVYLVDRVIPMLPERLSNNLCSLRPNEDKLCFSAVFELDDKANVIDQWFGRTVIHSDRRFSYEEAQEIIEGKEDTLAPAILKLNELAFILRDRKFKNGAISFESEEVKFHLDENGKPIGVYTKIRKEAHKLIEDFMLLANRKVAEFIGKQGRGKNKLPFVYRFHDVPNPETLTNFSQFASRFGHRLVIKSDKETAKSLNSLMTKIEGSKEQNLLTSLAVRSMAKAIYTTKKTSHYGLAFDYYTHFTSPIRRYPDVMVHRLLQYYLEGGNKINADHYEKMSEHSSQMEKKAAEAERASIKYKQAEFLQDQIGVEYTGIVSGVTEWGMYVEIEENKCEGMVRLRDITDDFYTLDEKNYAIIGQRKKKVYQLGDEVQIKVKKVDLEKRQIDFTLIS
>NZ_CP030848.1|WP_149525363.1|1502472_1503381_-|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVIEDFAPEECSKEFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSKLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSRVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149525364.1|1503550_1503859_-|DUF4342-domain-containing-protein
MSIKETFTITGENLLKRVKELIAEGNVTKISISDKSGKEIMSFPVTLGVIGVVLAPIFAAVGALAALLTECKITVERSEKPTEPEKEAAPEQNDGPRDIEVH
>NZ_CP030848.1|WP_149525365.1|1504012_1504798_-|TSUP-family-transporter
MEILGFIAAIGIGLILGLIGAGGSILTVPVMVYLFAIDPFLATTYSLFIVGISSLAGIVPYTLKRQVDFKTSIFFGLPSILGVFVSRRYIHPIIPNDIIQINGWMLSKDMLLMLLFAVLMVFAALNMIWKKEIATDVHQANDQIGKIIIQGILIGILVGLVGAGGGFLIIPALIIFNKMSLKTAIGSSLLIIALNSLFGFISSTNIDEIHWPLLLEITAIALAGMLLGSWISQKADAAKLKPFFGYFVLFMAIWILYQELH
>NZ_CP030848.1|WP_149525366.1|1504988_1505537_+|YeeE/YedE-family-protein
MELILGPWPWYVGGALVALIMVALIYLGKSFGFSSNFRNLCSALGAGKSCSFFDFDWKAQRWNLLFLVGSVIGGFVAAHYLSDNQVPAISESSIVQLKAIGIESAGAAYSPSEIFEVMSVKNILILAIGGLLIGFGTRYAGGCTSGHAISGLSDLQWPSLVAVIGFFIGGLMMVHVLFPLIF
>NZ_CP030848.1|WP_149525367.1|1505543_1505957_+|YeeE/YedE-family-protein
MRKVLFILLGILFGVVMYKAEAASWFRIYEMFNFQSFHMYGFIGTALVVGVIAVQLIKRTRAKDVDGGDIVIADKAKSIPRYLIGGILFGLGWALVGACPGPIFVLLGAGVYPMLIVIAFALLGTYLYGLLKHKLPH
>NZ_CP030848.1|WP_149525368.1|1506094_1507471_+|MBL-fold-metallo-hydrolase
MFFQQVYDKTLAQASYFIGCQAKKVAIVIDAQRDIDVYLDIAKQNNLEITHIAETHIHADFLAGSRELAEVTGAKLYLSDEGGENWQYEFAHEGLKDGDVVKVGNLSLTVMHTPGHTPESISFILRDHPASDEPVMIFTGDFVFVGDIGRPDLLEEAAGLIGTKEIGAEQMFQSLKKFVTLPDYVQVWPGHGAGSACGKALGAVPSSTVGYEKIRNWAFQFGDDYEGFKNYLLSDQPEAPTYFAMMKKLNKIDRPLLVEVPTHPTLSIEEGLAKTDSILVDTRNKVEFAKGHVKDSINIQNNNSLANWAGWMLPYDKKLVIVAEEGRQEEITRKLMRIGMDHIHGFVTDLSGVPLEETKLVDADTVAAWKDRDDTVLLDVRGKTEFETAHIPGAIHKFIGNLPKKLPTEYKDKKIIIQCQSGDRATIATSFLERNGFEKVYNYAGSFIDWKNKGKETT
>NZ_CP030848.1|WP_149525369.1|1507481_1508108_+|helix-turn-helix-domain-containing-protein
MSLIADAYQNILEPALIEEIEAVAIMKTFETGEVIIDIGQYVRSMPLLIDGAIKIVREDSKEGEILLYYLAKGETCTMSIACCVGTKKSEIRAQAEMHTLVAMIPNQYLNEWLAKYSSWREFILSSYSSRMNEMLGAIDNLAFSNMEMRIMNYLKEKVKLTENPILTLTHQDIASDLNSSRVVVSRILKKLENEEQIVLLRNEIRVLV
>NZ_CP030848.1|WP_149525370.1|1508126_1508711_-|sigma-70-family-RNA-polymerase-sigma-factor
MNKNFEQQILDLRAGKESALSFFMDSYAHSLRFFAMKMVKDKLISEEIVSDAYVKLWERKSNFSCAETIKSFLYLVTKNACLDYVKQGRLRFEHEEEWLYELENPDKDMLTKIIYFELLELIVKEIEKLPKQQAQIFKMSFFEGKNADEISSELGTSANNVYFARSKAISLLKETFKNKDISFYAMLISLISTN
>NZ_CP030848.1|WP_149525371.1|1508882_1509716_-|hypothetical-protein
MKQIITYIGLLILGLLAYACEPIEDRMELGSTITADQLDITAAPVIINGKKSNKVVLDNKSPVLSSWDFGTGTTQKKTDTVLLVTTGTSEIIFTGLNPEGTKITKKVEVTVDELTFPVPLEWGYLTGGTERNWKWDETAPAVWGNGGYLGNSAPAWWTLKEADINGQAPGEGIGAKMTFSLRGAKLTKTKSTGEKEEGAFSFDMTKVTKLDDGTVWAKGKLTTRGVTVLCGKSPNEGNAPVYEYDIMILNNEKMILSYAEPGAAAWGTAWFWVFRAE
>NZ_CP030848.1|WP_149525372.1|1509735_1511427_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKTIILLATAFLMTSCEKFLDTDSLDKKNTGNFPVNVADANQMLTGIYASLSRAVSNPQHSHFYMAELASDDRFGGGGENDRDMQGLDHLMNTQPDRFLNFWEARYEGIFRANTAIETLDKVSGWSGDAEKNQLLGEVHFLRALYYFELAQMFGEVPLLVESVATVKPKASADEIFAQIAFDLQKAIELIPARAYNAVPSGHATKWAAQALLARAYLFYTGYYKKADLPVAGGGTIAKNLVIQHLEDCIQNSGHNLVPEFRNLWPYSNEHTAKDYEYAKDNNLKWVGDGHMETVFAVKFGTLADWGDQYILGYSNQYLLHFGLRSNNGLAGTFPFGQGWGAGPVNTSLWNEWRQAEPTDIRRTASIINADVDLQDYVYGADNQMEETGFWQKKYIPVTAYREGALLPSYAVLSDAAAVDYQLAHTQDLVLIRFADVLLMHAELKEDATNLNRVRARAKLPAVAYSLAALKRERRWELAFEGLRYFDLMRWHDAADALAKQEGVTIKNKGVNTAMKGFGGGYKARYEATGGFWAIPNSEIILTDGVLTQNKGWGTPAAEFTGW

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Crispr_ID: NZ_CP030848_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_4

1579692-1579792

Orphan

Consensus_repeat	Method
TGAACCAGGAAAGGAAGGATGTAAGGATTGGCAGGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_4

>merge|NZ_CP030848|4|1579692-1579792|CRISPRCasFinder
TGAACCAGGAAAGGAAGGATGTAAGGATTGGCAGGATAGTATTGTTTAGAAAAGGAAGTTCGTCTGAACCAGGACAGGAAGGATGTAAGGATTGGCAGGAT

>NZ_CP030848|4|4|1579692-1579792|CRISPRCasFinder
TGAACCAGGAAAGGAAGGATGTAAGGATTGGCAGGAT	AGTATTGTTTAGAAAAGGAAGTTCGTC
TGAACCAGGACAGGAAGGATGTAAGGATTGGCAGGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525415.1\|1577302_1578073_+\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|179028
NZ_CP030848.1\|WP_149525419.1\|1581050_1584110_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149525411.1\|1572353_1573598_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238153
NZ_CP030848.1\|WP_149525420.1\|1584119_1585586_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
NZ_CP030848.1\|WP_149525413.1\|1574606_1575953_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP030848.1\|WP_149525416.1\|1578079_1579453_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|379851
NZ_CP030848.1\|WP_149525414.1\|1576134_1577199_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380530
NZ_CP030848.1\|WP_149525421.1\|1585590_1587204_+\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293749
NZ_CP030848.1\|WP_149527661.1\|1591039_1592134_+\|alginate-lyase-family-protein	unknown	unknown	gnl\|CDD\|377511
NZ_CP030848.1\|WP_149527662.1\|1595471_1597076_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|369630
NZ_CP030848.1\|WP_149525409.1\|1569480_1570671_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349882
NZ_CP030848.1\|WP_149525423.1\|1592277_1595406_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149525422.1\|1587387_1588263_+\|DUF808-family-protein	unknown	unknown	gnl\|CDD\|377542
NZ_CP030848.1\|WP_149527663.1\|1597134_1597617_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|183451
NZ_CP030848.1\|WP_149525408.1\|1568389_1569454_+\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|188630
NZ_CP030848.1\|WP_149525407.1\|1567367_1568390_+\|epimerase	unknown	unknown	gnl\|CDD\|187575
NZ_CP030848.1\|WP_149525412.1\|1573587_1574595_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP030848.1\|WP_149525418.1\|1580303_1580597_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	unknown	unknown	gnl\|CDD\|378301
NZ_CP030848.1\|WP_149525410.1\|1570872_1572342_+\|Na+:solute-symporter	unknown	unknown	gnl\|CDD\|271371
NZ_CP030848.1\|WP_149525417.1\|1579947_1580301_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227786

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525415.1\|1577302_1578073_+\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	2.19494e-104
NZ_CP030848.1\|WP_149525419.1\|1581050_1584110_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP030848.1\|WP_149525411.1\|1572353_1573598_+\|hypothetical-protein	gnl\|CDD\|238153	cd00249, AGE, AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases.	1.28077e-20
NZ_CP030848.1\|WP_149525420.1\|1584119_1585586_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	1.27146e-46
NZ_CP030848.1\|WP_149525413.1\|1574606_1575953_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	8.81503e-30
NZ_CP030848.1\|WP_149525416.1\|1578079_1579453_+\|oxidoreductase	gnl\|CDD\|379851	pfam16490, Oxidoreduct_C, Putative oxidoreductase C terminal domain. This is the putative C-terminal domain of a bacterial oxidoreductase. It lies C-terminal to family GFO_IDH_MocA pfam01408 in some members.	1.19849e-149
NZ_CP030848.1\|WP_149525414.1\|1576134_1577199_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380530	cd06307, PBP1_sugar_binding, periplasmic sugar-binding domain of uncharacterized transport systems. Periplasmic sugar-binding domain of uncharacterized transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily. The members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes.	6.46396e-42
NZ_CP030848.1\|WP_149525421.1\|1585590_1587204_+\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293749	cd16025, PAS_like, Bacterial Arylsulfatase of Pseudomonas aeruginosa and related proteins. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	0
NZ_CP030848.1\|WP_149527661.1\|1591039_1592134_+\|alginate-lyase-family-protein	gnl\|CDD\|377511	pfam05426, Alginate_lyase, Alginate lyase. This family contains several bacterial alginate lyase proteins. Alginate is a family of 1-4-linked copolymers of beta -D-mannuronic acid (M) and alpha -L-guluronic acid (G). It is produced by brown algae and by some bacteria belonging to the genera Azotobacter and Pseudomonas. Alginate lyases catalyze the depolymerization of alginates by beta -elimination, generating a molecule containing 4-deoxy-L-erythro-hex-4-enepyranosyluronate at the nonreducing end. This family adopts an all alpha fold.	2.21758e-81
NZ_CP030848.1\|WP_149527662.1\|1595471_1597076_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	7.75575e-36
NZ_CP030848.1\|WP_149525409.1\|1569480_1570671_-\|amidohydrolase	gnl\|CDD\|349882	cd03886, M20_Acy1, M20 Peptidase Aminoacylase 1 family. Peptidase M20 family, Aminoacylase 1 (ACY1; hippuricase; acylase I; amido acid deacylase; IAA-amino acid hydrolase; dehydropeptidase II; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14) subfamily. ACY1 is the most abundant of the aminoacylases, a class of zinc binding homodimeric enzymes involved in the hydrolysis of N-acetylated proteins. It is encoded by the aminoacylase 1 gene (Acy1) on chromosome 3p21 that comprises 15 exons. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney, suggest a role of the enzyme in amino acid metabolism of these organs. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D), resulting in a metabolic disorder manifesting encephalopathy and psychomotor delay.	6.29442e-151
NZ_CP030848.1\|WP_149525423.1\|1592277_1595406_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP030848.1\|WP_149525422.1\|1587387_1588263_+\|DUF808-family-protein	gnl\|CDD\|377542	pfam05661, DUF808, Protein of unknown function (DUF808). This family consists of several bacterial proteins of unknown function.	1.65557e-106
NZ_CP030848.1\|WP_149527663.1\|1597134_1597617_+\|hypothetical-protein	gnl\|CDD\|183451	PRK12336, PRK12336, translation initiation factor IF-2 subunit beta; Provisional.	0.00493673
NZ_CP030848.1\|WP_149525408.1\|1568389_1569454_+\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|188630	cd00408, DHDPS-like, Dihydrodipicolinate synthase family. Dihydrodipicolinate synthase family. A member of the class I aldolases, which use an active-site lysine which stabilizes a reaction intermediate via Schiff base formation, and have TIM beta/alpha barrel fold. The dihydrodipicolinate synthase family comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways and includes such proteins as N-acetylneuraminate lyase, MosA protein, 5-keto-4-deoxy-glucarate dehydratase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, trans-2'-carboxybenzalpyruvate hydratase-aldolase, and 2-keto-3-deoxy- gluconate aldolase. The family is also referred to as the N-acetylneuraminate lyase (NAL) family.	2.17524e-15
NZ_CP030848.1\|WP_149525407.1\|1567367_1568390_+\|epimerase	gnl\|CDD\|187575	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1. Atypical SDRs in this subgroup are poorly defined and have been identified putatively as isoflavones reductase, sugar dehydratase, mRNA binding protein etc. Atypical SDRs are distinct from classical SDRs. Members of this subgroup retain the canonical active site triad (though not the upstream Asn found in most SDRs) but have an unusual putative glycine-rich NAD(P)-binding motif, GGXXXXG, in the usual location. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0.000541544
NZ_CP030848.1\|WP_149525412.1\|1573587_1574595_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	5.55872e-20
NZ_CP030848.1\|WP_149525418.1\|1580303_1580597_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	gnl\|CDD\|378301	pfam09907, HigB_toxin, HigB_toxin, RelE-like toxic component of a toxin-antitoxin system. HigB_toxin is a family of RelE-like prokaryotic proteins that function as mRNA interferases. HigB cleaves translated mRNA only, and cleavage depended on translation of the target RNAs. HigB belongs to the RelE super-family of RNases. The toxin-antitoxin gene-pair is induced by environmental stress factors.	1.81222e-21
NZ_CP030848.1\|WP_149525410.1\|1570872_1572342_+\|Na+:solute-symporter	gnl\|CDD\|271371	cd11477, SLC5sbd_u1, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	9.90033e-131
NZ_CP030848.1\|WP_149525417.1\|1579947_1580301_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|227786	COG5499, COG5499, Predicted transcription regulator containing HTH domain [Transcription].	5.89995e-18

>NZ_CP030848.1|WP_149525416.1|1578079_1579453_+|oxidoreductase
MKKLAIALLVLATLNSCKTEKETTSDKLTLMTLDPGHFHASLIQKSMLPGIDSVCYVYAPKSLGVSAHNALLNEYNIREENPTGWKVESYTDSDFLEKMLEEKPGNIVVLAGNNKRKTDYIHKSVSAALNVLSDKPMAINKEGFNLLIDAFDVAKDKQVLLYDIMTERYNIFSILQKELVHNADLFGTLEKGTIDNPAIIKNSVHHFFKEVSGKPLIRPDWYYDVEQEGEGIVDVTTHSIDLIQWQLFPENVFDYKADVEVLNANRYPTKISLAEFEQSTGDAAFPGFLQKDVKNDTLNVYANGEINYSLKGVHSKVAVQWNYQAPEGSVDTHLSQIRGTRSIVSIKQGKEQNYKPRLYIEPAAATGFTEDDKKAINAGFETIASKYKGIALKAEGNGYVVDVPADLLEGHEEHFAHVANKFLDYVRAGEMPEWEKSYMLTKYYITTEALAKAKTLR
>NZ_CP030848.1|WP_149525415.1|1577302_1578073_+|glucosamine-6-phosphate-deaminase
MDAKELEVGTLKVYTFENREELGLYAGKKAAARIKELQETPDKIVRMIFASAPSQLETLAYLRKDEGIDWSRVVAFHMDEYVGIEKNHPQSFASFLEQNLFDQVNIGQVHFINGIAEDPQAECERYEALLKEAPIDIVCLGIGENAHIAFNEPHLADFADPHFVKLVDLDLTSRQQQVNDGCFLTLEEVPTHAITLTVPALFAGQSLFCMVPGSTKATAVHATLNGEITTEIPSSILRTHPQVSLFIDKDSAAQLN
>NZ_CP030848.1|WP_149525414.1|1576134_1577199_+|substrate-binding-domain-containing-protein
MEKKQKELNGVKEIARRAKVSIATVDRVLHNRPGVSEKTKQKILEIIKELDYKPNILARRLASSKTMHLYTLIPEKSKETDYWDVPLQGIFQAENEIKLYNVKVSKFFYDMNDKQSFIEQTKNILKQTDIDGLLLAPAFVEEAVAFTEECKRRNIPFVFINSDIPQQKSLSYFGPNLFHSGQTAAHLIHYLTKETDQLLLLNIAKDIDSDHHILRKEEGFMSYFNDNKPRNIIKENLYDTNYTAVKKALAKIVKSNPDLHLIFVTNSRVALVAKFLQEIGKNDILLIGYDFLPNNIEYLNQGMIDFLICEKPQEQAYRGIKALYRFLMFEEDQEKEYFMPIDIIHRENQQFYKN
>NZ_CP030848.1|WP_149525413.1|1574606_1575953_+|Gfo/Idh/MocA-family-oxidoreductase
MEESRRNFIKKAVIGTTAMTFGGILPSFSAKSYGNIIGANERINIAMMGVNARGKALANNFALQPNSQITYICDVDSGAIDRCMPEVMKRQKHQPKTEGDFRRALEDKDVDALVVAAPDHWHAPAAILASSAGKHVYLEKPCSHNPHEGELLIEAVKKYKNVIQMGNQRRSWPNVAAGIREVHNGAIGKAYFAKTWYTNNRAPIGVGKEVAVPNRLNFDLWQGPAPRRAYKDNILHYNWHWFWHWGTGEALNNGTHFVDLARWGLQVEYPTRVTSVGGRFAHKDDWETPDTQTIGLEFGNNSMITWEGRSCNGMKTDGATVGVVFYGEKGSLQINGDNAYQIFDLNSKLVKEVRDTTKVEATSLTNPSQQLDAIHIQNFFSAIKDGSALNSDIIGGHQSTLLVQLGNIAQRTGQALDIDPKTGKILNNKEAMNKYWKREYQRGWEPRV
>NZ_CP030848.1|WP_149525412.1|1573587_1574595_+|Gfo/Idh/MocA-family-oxidoreductase
MKNDVSRRGFIKTTAMASLGIGMLGPNTKFFEGLSSVQKGKRVGIIGLDTSHATAFTKSLNGENPDPRFKGYKVVAAVAQGSKDIPSSVERVPKYIEEVKKYGVEIVKDINALLKKVDVVLLESNDGRVHLEQAIPVIKAKKTLFIDKPIAASYKDAKQIFDLAKQNNVPVFSTSSLRFMDKVKEVKGGSVGKVLGADTFSPAALEPNHPDFFWYGIHGIEILFALMGTGCESVTRVHTEGTDVVVGKWKDGRIGTFRGLRVGKHDYGGTVFGEKGNTTLGQFKGYDSLLLEIIAFFETGNPPVSAEETLEICAFIEAADESKRQQGKPVSLVTS
>NZ_CP030848.1|WP_149525411.1|1572353_1573598_+|hypothetical-protein
MNSIQINRQTAFTNETLYMMLEQYKQYLFDDYLPFIDEYVYDKEHGGYFWNTSYKGKQLSSHKRTWYDARGTWVYSYLYKVLDTDPQYLERAKQTLKLLFKAKDTGARFWPWSYDQAGNDLQEREGDIYGNLFVAEALAAYSDASGEQDAWDEAKNILQEAFALYQTKEYRYLLEYTPTKDYPEAEEILGHYMIVLHLCTTLLRLQADTELEEIADYCLEALLQKHYDAELNLMPELRSKAGSGLGESLDQFVYIGHAIETLWMIMDEAKRRKDQELFDLAASRFKFHVEVAKDDLFGGFFHCLDHAKENRFLLDKVLWAQEEVMVGCLILMEERSDEWAYHTFQNTLQYLQQQFILDHLPYKPWKINGNRQMNREEEGIRIENYHHPRHLIFGILTLQKIINRITLNLNSYEK
>NZ_CP030848.1|WP_149525410.1|1570872_1572342_+|Na+:solute-symporter
MQPIDYIVIVVFFFLLIGIGIYSYFKVSSSADFFTAGGKLPWWLSGISHHVSGYSGAVFVAYASIAYTHGFVMYVWWALTIAIAMIGTIIFIAPRWARLRTKTGIQSPTEYLATRYNLPVQQLMAWCGVIVKLFDVGAKWAAVGILLNAFMGIPIVTGIILSGVVTLFYVTLGGLWADVLNDFMSFLIQVASGLVMFFVVLMHLGDGASGVFTMWDRLPPENSNLFNSPYTVGFAMAFLVINFFSYSGGTWNLATRFISSPSGKDAKKAAILSAILYLVWPLILFYPMFAAPIFFPNLEKPETSYSLMAMEFLPPGLLGLLVASLFSTTLSMTSSDANTISSVITRDILPVMIKKVKTFDKPKMLLVARITTFSFLVMTIIIAFNAQTFGGVIGLIISWFAALLGPISIPMILGLLPYFKHSGSIAALLSIIGGLATFVILKLIGGTGLAVELAGPLITSLVLYIGYAFVAKGEVPEKTEKLLDAINEE
>NZ_CP030848.1|WP_149525409.1|1569480_1570671_-|amidohydrolase
MNPIEYIQTQDKHILEKVVQWRRHLHQHPELSFEEKETTKYIASVLDGMGIPYEQVSPTGLIGIIHGNGSSEKSIALRADIDALPITEENKHGYASLNKGVMHACGHDFHSSNLLGVAYLLNEIKHTLNGNVVLIFQAAEERIPGGAAAIVESGILDRYQVQKVIGQHVSPQLPLGTFGFKSGYAMASSDEIYIDIMGRGGHGAQPQLNIDPVIISAQLLVGLQQVVSRYADPRIPSVLSFGKVIADGAANVIPTTVHLAGTFRTTDEQWRASALAKIENLIVQTVDAYGASAKIEIKRGYPTLYNDPSLTAEMQQLATNLYGAESSLSVPTWMASEDFAYYAQKYPALFYFVGTRNEEKGIVSELHTPTFEIDETIYERSVEFMFKGAVSVLQRL
>NZ_CP030848.1|WP_149525408.1|1568389_1569454_+|dihydrodipicolinate-synthase-family-protein
MKKLTKELKDFLMEGQVFPAHPLALNEDRSLDEASQRRLTRYYMESGAGGVAVAVHSTQFEIRDPNINLFRKVLELAADEIDKAKLDRPFLKIAGICGPTEQALEEAAIAVELGYDIGLLSMGGLQGWTEEAILERVRKVAQVIPVFGFYLQPSVGGRIFSYDFWSSFVEIEGVEAIKCASFNRYQTLDVMRALANSSRADDVAMYTGNDDNIVADLLTTYDFQVDGLTKSIDFRGGLLGHWAVWTKKAVELMQQVKQAKASKDYHHLNALLSKGVKVTDSNAAFFDPAHDFHGCIPGIHEVLRRQGLLKGIWCLNPDEVLSEGQAEEISRVYDNYPELNDDTFVKSFLAKDSA
>NZ_CP030848.1|WP_149525407.1|1567367_1568390_+|epimerase
MFVMDLKKLEEKYAVPSRELVEDVKQIEGDIMLLGIAGKMGVSMGKLLVDALKLAGKENKVYGVSRFSDPKAKSQVEESGIIAIACDLLNDEQLFNLPDVANVIYLAGHKFGTVGNEDFTWAMNTYLPGRVSEKFKDAKIVAFSSGNILPFVKLNEGGVDEDAVPQPIGEYAQSCLGRERVFQYFAKKNNTPMLIYRLNYAVDFRYGVIMEIGKSVWNEKPIDLRTENVNVIWQGDANEIAIRSLLHCESPAKILNVTGPETLSTKWVAKEFAKIFGKEAKFVHEAEGTALLNNASECHRLFGYPKVTIREVIELNAAWIQNGGDEFGKPTHFQERGGQF
>NZ_CP030848.1|WP_149525417.1|1579947_1580301_-|XRE-family-transcriptional-regulator
MWYLLENDNEYKNALKRFEEIKYSKRGTVEHKEKMLLVTLISNYEVKKYPVTEIDPIEMIKIRMKEFGYSASQLGNKSTVSKILNYKRPLTLSMIRHLSKLLKIPSDFLIQEYQLKP
>NZ_CP030848.1|WP_149525418.1|1580303_1580597_-|type-II-toxin-antitoxin-system-HigB-family-toxin
MIILKLELLDRFKKKHASSRKGIDAWIILVRSAQWLKSQDIIDDFPTAKIISADRARFKIVGNKFRLIIEVAYKDGYVDVRFIGTHAEYDKIDAKNI
>NZ_CP030848.1|WP_149525419.1|1581050_1584110_+|SusC/RagA-family-TonB-linked-outer-membrane-protein
MKNIGVLRYFSLLLWAFSLFNSTLYAQDKPKPIINASLEGVVLDSLTRQPIEGVTIQLDAVTHAVKTDQEGRFQFVTGQKLPFTIKVSFLGYKTKNLVVDVSPTAILLSPSSEDLDEVVVVGYGTQRRRDLTGAVGSVPESFLNQKVSSVDQSLKGAISGVQVTQTSGQPGAGVSIRVRGGASIQGGNEPLYVIDGFPVYNQSESTGVNSGTPINPLASINPNDIESIEVLKDAAATAIYGSRGANGVVIISTKKGRAGRVQLNYDGSKGWQSVVKQIDVLDAQSFARLRNETLYDTNPSRGKFQYLSEEQISQLGEGTNWQNEAFRVGEVQNHQLSLTGGAERIQYYLGANYLNQEGVVVNTDFRRLGFRSNLHAKPFERLDVSANLTINKTNSQIAPTGIINSLLIMPPTATIYEADGSYTLRNPFENIFANPIATLLETSNESNNLRVLGTAYAQYELLKGLSAKVLFGVDLSNRNDKYYLPSYIYEGSGSKGTANLGNLENQAWLNENTLTYSKSFGQHDLNVLLGFTQQESSTSLFNAGASSFVTDELLYNNLQSGSVLIRPNSDAYDWVLHSLLSRINYNYANKYYVSASIRRDGSSRFGSANKWGNFPSLAFSWRASKEDFFTGLLPTINDLKVRASFGATGNQEIGQYQSLATLYALNYYFGNAVQTGFASQRVPNAELGWETTYQYDAGIDLAFLQNRIQISADYYYKRTKNLLLSVEIPWTSGYATSLQNFGSVSNKGVELSIKSKNVQGAFNWGSDFNISFNRNKVLSIGDGSERYINGNYLIAVGKPLGTFYGTVTDGILQLGEEATKGVYTGNANPKAGDRLYKDIDGDGKFSTANDRTIIGNAQPDFIFGFSNNFSYQGFDLSFLIQGTVGNQILNINRQNLEMFTGQQNASIDALARWTPENTTQVYPRAKLDPAPIFSDQFVESGTFVRLANLRFAYSLPKTWLSSAHINHAQVYFIGQNLLTLTNYRGFDPEVTSGSNVQIGTDAGIYPVAKTLSLGLSLTF
>NZ_CP030848.1|WP_149525420.1|1584119_1585586_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MRKRYLPIVLLISLLATACSKLDEQPRAILVNEQFYLDEAQAVAAVTGTYRKLYETGQSLYNSLFQIGVEMATDDYEAGPRARNAHVRAISNLTHDASNDRMEQLWKQSYDAINASNLNIVAIEKIPADKIDATIQKRLILEARFLRALHYFNLVRWFGDVPLQLQPIANLSKAELQVAKSTEEQVYLQIIADLQAAEALPNYKAYGDTDRGRASSGAAKSLLAKVYLTQKDYAKAKAKAAEVIEQEGYELFEEFADVFNVETKNGKEHIFSAQFKGNVGYQGNSLAGRSAPADIPGINGDYADALHVQGGLYEAYEKTDARLAVTFTLGKVSPVDGKYYALPTPQFNKYYDDAVVGNQSQSSKNLPIIRYAEVLLIFAEAENELNGPTAAAKDALNAVRQRAKTTLLTTSVSKDAFRESVFEERRKELVYEYQRWFDLVRRGADYYVAKLKAAGKINASARHLHFPTPQRELNLNPNLKQHPDWINH
>NZ_CP030848.1|WP_149525421.1|1585590_1587204_+|sulfatase-like-hydrolase/transferase
MNRKNIFLNTVLLLLSLSVWAQDKRPNIILILADDLGYSDLGSYGSEIPTPNLDRLAKEGLRLREFYNNSICAPTRASLLTGQYQHKAGVGYFSNDLGLSAYQGYLNKESLTIAEVLKENGYITLTSGKWHVSEKGQSYPWERGFDYVYPRDDKNANSGAPGLRTPETDAEGYPTQATFSTNLITRNAIGFLDSIKSRQEPFFLYLAHTAPHWPLVAPKEDIARFKGKYDMGWSVLREQRLKRQREIGLIPTGLTPSTADRDLYDWEKLTAEQRAGWAKKMEIFAAMVYRLDQSIGELLDRLEKNGQLDNTLIVFLSDNGAPAEDLVRWHHGSDRNKGAIGTVTSYESQSKNWSYASNTPFKAFKDYMYEGGINTPFIAWFPGRIQQGEIKQGTGHIIDLAPTFYELANAKYPEAYKATKVNALAGKSLLPLLTSESQQVLREEGLFWERAGNRAARVGKWKLVSTWPSQTWELYDLESDPTETRNIADKNEDVVSRLAQAYANWAKETGVVDFAELESKEPASMKEFRKSKVQEVE
>NZ_CP030848.1|WP_149525422.1|1587387_1588263_+|DUF808-family-protein
MASGIFAVLDDIAALMDDVAVASKLATRKTAGILGDDLAVNAEKATGFLATREIPVLWAITKGSFINKLIIVPIALILNAIFPIAIKYILILGGFYLAYEGVEKIVHYLFHRKKEGHEVIQKNVEQGEIAENAKIKSAITTDFILSVEIVIIALGTVLDQSLTIQILTVSVVAIIATIGVYGIVALIVRMDDMGYSLIKRSNDKGFAAKFGHALVKLLPLVIKSLGVIGTIALLMVSGDIFVHNIDYLHHMLPSLPGIVKSIAAAIVGGLIALGLVTVGKALFGKKEKAHA
>NZ_CP030848.1|WP_149527661.1|1591039_1592134_+|alginate-lyase-family-protein
MTTTVVNKLRPEVLAAADKALEEPIRTITSATSERSLGTKNDFYSEGDYWWPNPEDNDGPYIRKDGMSNPDNFVAHRELVMRYGDIISDLVSGWLLTKDDRYAKRAMEHAKAWFVDKNTRMNPSMNYAQAIKGVASGRGIGLIDGIHFVEVARSLEHLKTAGKLNEKDGKAIEEWFASYLNWMNTHPYGLDEKATKNNHASCWLLQAAAFARYTNNQAMLDSCVQRYQQVILPNQMASNGSFPLEIERTKPYGYSLFNLDIFAGITRILQKHNSQAAEITVDGKNLEKGIDFMFPYVVDKTKWPYEKDVMYWDNWPIAHPFLLFGALDFQREDLLNTWLKLPLDYSELEVRRNSPMRHPLIWIL
>NZ_CP030848.1|WP_149525423.1|1592277_1595406_+|SusC/RagA-family-TonB-linked-outer-membrane-protein
MMRSCIHLSRSCCIIIGLIFLVQLSYAQALRTIQGVVRLQDGTAAANVSVSIKNSQQETSTNEAGDFRLQASNAAVLQFRLLGYQTQEVTVGTQSTINVVLVENQENLDEVVVVGYGTQKKVNLSGAVSQVAGEELVDRPNVNLTSALQGVLPGVAVTRSSGNPGDEGSGIRVRGFSSANSMSALVLVDGIEMDLNLINPDDVESISVLKDASASAIYGARAAGGVILVTTKKGKAGKPVVNYNNYYGVNIAARRPERLNSWDEQLLIDEARLNATGNPEFTEEQREWLMNPNFSYRPNPTQDRWEYFGNNNWIKEGMNKYSDMHNHNLSLSGGGEKVTYNVSGGYYNRSGVLRYGPDDNSRYTLRTNLSAEVNKYVQLNIAANYVGSEVNQNAYGTQQIINRMYRSRTRQSLYVPAEDITGQPFNGDLQINPIDIQQNGGLYRRLYESFTGRANLKIKNIVEGLTIDITGSRNQDYYNMQRDRRTIIWYGRSTNTIRSKVNDPNSTERAKNRGFLNNLQAVATYNFKVAENHNFTLLAGTSFEEYRKDELVAGAQSLITNDFYSLNYGNPATKTNGDDIQTWAMGSYFGRLNYNYKERYLLEASFRYDGSSRLAPENRWELFPSFSAAWRLDQEEFMKDQTIFDLLKIRASWGQLGNGASLGLYDYIPLLSSGLRESASDNPYLVFNDVREQYLFQKQLASPQKTWEVVQQSNIGIDFAILKNRLSFTGDYYVKRNKNMLAALNLPSIIGIDVPFFNVGELKSWGWEFDIKWKDKINDFRYSVGFNLSDNQNELVRFDGRNIINEGVVDLLEGYPMNTVWGYKTDGYFQTKEEYDAYKAQVNTPFFPNNAGAGDVKYLDVNGDSVISAGEGTPNSPGDLVNYGTSNGRYFYGFNMGFQYKGFDFSAMLQGVAKRVFVISTETLSPMLGTADLPWTIHMDRWSPENPDATFPRMYQTSSHNYRPSDKWIQNGAYLRLKNVQLGYTLPLKTQAIRKLRVFFSGQDLWETTKVMEVFDPEVPNNVGATTYPFFRTVSFGLNLTL
>NZ_CP030848.1|WP_149527662.1|1595471_1597076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MTASCSLDRFPETTFSDQEFWNTESDLKFAANRLYQQLEGFDLDNRGDDNVNQTVNLISNGAWSIPSTSSDWSQPYEMIFTANNILIKGEKAGVAEEIKNRYFAEAKFFRAYAYFQLVQRYGDVPFLTKTLDFNSPELNMARTPKAEIAKQLYEDLDYAKDWLPTAKSIPAADYGRVSKSAAQALKARIGLFLGTFAKYHGGSDAQTHLQQAVDGATYVMGQGHQLFSDYAKLFNQEGEGPGNSENILVKIYGVDASNVILAHNYSRDLENGRVAVTRNLIRQYLYTDGLPAYNERNELKPMRSAFYIAEGAEPSYNAVLDNRDPRLGLTVFRDGEQAYKGPWVPTTTLGARTAYATKKGFNIPDWQTSGSATTDRILIRYAEVLLTYAEAKYELNGSISDEDLDKSINLLRSRVGMNVKLSNAFAAANQLSMLEEIRRERNVELALEGFRYPDLIRWKLAENALTQDILGAKYNATDWVGADIKNLNLNADQILIVEDKSTRRFNPAKDYLYPVPLNEISLSGGAVVQNPNWK
>NZ_CP030848.1|WP_149527663.1|1597134_1597617_+|hypothetical-protein
MAVTSLFACKEDREVLPGLPEYEHHYYVVYMPNNNSAVTVKRSQTALLELPVQFYSEFERNYDAIAHYVVSIDGINNPAELGKDFEVVDASGNKISPIAGKYQIVFPGAKKAQAKIYIKLLNNTAATGRRSVAINLVDNIQEQFRVDVFSTAFKRTVNID

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Crispr_ID: NZ_CP030848_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_5

1874028-1874125

Orphan

Consensus_repeat	Method
AATGTTGTCTTGAACCAGGAAAAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_5

>merge|NZ_CP030848|5|1874028-1874125|CRISPRCasFinder
AATGTTGTCTTGAACCAGGAAAAAAATGATAAAAGGATGGACAGGATAGGGGCTGATGTCGTGTTTGTTGGAAATGTTGTCTTGAACCAGGAAAAAAA

>NZ_CP030848|5|5|1874028-1874125|CRISPRCasFinder
AATGTTGTCTTGAACCAGGAAAAAAA	TGATAAAAGGATGGACAGGATAGGGGCTGATGTCGTGTTTGTTGGA
AATGTTGTCTTGAACCAGGAAAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525618.1\|1888474_1889518_+\|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|99810
NZ_CP030848.1\|WP_149525612.1\|1876035_1878360_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|227342
NZ_CP030848.1\|WP_149525606.1\|1866126_1868052_-\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|130728
NZ_CP030848.1\|WP_149527673.1\|1868298_1868826_-\|isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl\|CDD\|239218
NZ_CP030848.1\|WP_149525605.1\|1865546_1866050_-\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP030848.1\|WP_149525617.1\|1884731_1887755_+\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NZ_CP030848.1\|WP_149525616.1\|1883391_1884630_+\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|236410
NZ_CP030848.1\|WP_149525611.1\|1874343_1875807_-\|RNA-polymerase-factor-sigma-54	unknown	unknown	gnl\|CDD\|235648
NZ_CP030848.1\|WP_149525613.1\|1881595_1881919_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|198395
NZ_CP030848.1\|WP_149525615.1\|1882924_1883389_+\|ribosome-assembly-cofactor-RimP	unknown	unknown	gnl\|CDD\|179358
NZ_CP030848.1\|WP_149525614.1\|1882034_1882808_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP030848.1\|WP_149525608.1\|1870141_1870816_-\|DUF937-domain-containing-protein	unknown	unknown	gnl\|CDD\|368733
NZ_CP030848.1\|WP_149525603.1\|1864726_1865041_+\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|370057
NZ_CP030848.1\|WP_149525607.1\|1868893_1869931_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|224919
NZ_CP030848.1\|WP_149525610.1\|1873364_1873622_-\|5-oxoprolinase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525604.1\|1865009_1865501_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP030848.1\|WP_149525478.1\|1872000_1872909_-\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525609.1\|1870883_1871984_+\|DUF2891-family-protein	unknown	unknown	gnl\|CDD\|378592
NZ_CP030848.1\|WP_149527674.1\|1878478_1881529_+\|tolB-protein-precursor	unknown	unknown	gnl\|CDD\|223893
NZ_CP030848.1\|WP_149525619.1\|1889526_1891194_+\|peptide-N-glycosidase	unknown	unknown	gnl\|CDD\|378122

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525618.1\|1888474_1889518_+\|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl\|CDD\|99810	cd06214, PA_degradation_oxidoreductase_like, NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like domain with an iron-sulfur binding cluster domain. Ferredoxins catalyze electron transfer between an NAD(P)-binding domain of the alpha/beta class and a discrete (usually N-terminal) domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal portion may contain a flavin prosthetic group, as in flavoenzymes, or use flavin as a substrate. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria and participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	2.21373e-80
NZ_CP030848.1\|WP_149525612.1\|1876035_1878360_+\|penicillin-binding-protein	gnl\|CDD\|227342	COG5009, MrcA, Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane].	9.06938e-153
NZ_CP030848.1\|WP_149525606.1\|1866126_1868052_-\|FUSC-family-protein	gnl\|CDD\|130728	TIGR01667, Uncharacterized_protein_HI_1680, integral membrane protein, YccS/YhfK family. This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane.	9.49688e-34
NZ_CP030848.1\|WP_149527673.1\|1868298_1868826_-\|isopentenyl-diphosphate-Delta-isomerase	gnl\|CDD\|239218	cd02885, IPP_Isomerase, Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated proteins. These compounds are synthesized from two precursors: isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). IPP isomerase catalyzes the interconversion of IPP and DMAPP by a stereoselective antarafacial transposition of hydrogen. The enzyme requires one Mn2+ or Mg2+ ion in its active site to fold into an active conformation and also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as a metal binding and catalytic site. The metal binding site is present within the active site and plays structural and catalytical roles. IPP isomerase is well represented in several bacteria, archaebacteria and eukaryotes, including fungi, mammals and plants. Despite sequence variations (mainly at the N-terminus), the core structure is highly conserved.	6.76057e-73
NZ_CP030848.1\|WP_149525605.1\|1865546_1866050_-\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	8.47232e-10
NZ_CP030848.1\|WP_149525617.1\|1884731_1887755_+\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_CP030848.1\|WP_149525616.1\|1883391_1884630_+\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|236410	PRK09202, nusA, transcription elongation factor NusA; Validated.	1.34585e-162
NZ_CP030848.1\|WP_149525611.1\|1874343_1875807_-\|RNA-polymerase-factor-sigma-54	gnl\|CDD\|235648	PRK05932, PRK05932, RNA polymerase factor sigma-54; Reviewed.	4.82528e-145
NZ_CP030848.1\|WP_149525613.1\|1881595_1881919_-\|hypothetical-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	4.44388e-08
NZ_CP030848.1\|WP_149525615.1\|1882924_1883389_+\|ribosome-assembly-cofactor-RimP	gnl\|CDD\|179358	PRK02001, PRK02001, ribosome assembly cofactor RimP.	1.87672e-34
NZ_CP030848.1\|WP_149525614.1\|1882034_1882808_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.76424e-13
NZ_CP030848.1\|WP_149525608.1\|1870141_1870816_-\|DUF937-domain-containing-protein	gnl\|CDD\|368733	pfam06078, DUF937, Bacterial protein of unknown function (DUF937). This family consists of several hypothetical bacterial proteins of unknown function.	4.86913e-14
NZ_CP030848.1\|WP_149525603.1\|1864726_1865041_+\|DUF1778-domain-containing-protein	gnl\|CDD\|370057	pfam08681, DUF1778, Protein of unknown function (DUF1778). This is a family of uncharacterized proteins. The structure of one of the hypothetical proteins in this family has been solved and it forms a helix structure which may form interactions with DNA.	1.8862e-19
NZ_CP030848.1\|WP_149525607.1\|1868893_1869931_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|224919	COG2008, GLY1, Threonine aldolase [Amino acid transport and metabolism].	8.13896e-106
NZ_CP030848.1\|WP_149525604.1\|1865009_1865501_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.29021e-10
NZ_CP030848.1\|WP_149525609.1\|1870883_1871984_+\|DUF2891-family-protein	gnl\|CDD\|378592	pfam11199, DUF2891, Protein of unknown function (DUF2891). This is a bacterial family of uncharacterized proteins.	0
NZ_CP030848.1\|WP_149527674.1\|1878478_1881529_+\|tolB-protein-precursor	gnl\|CDD\|223893	COG0823, TolB, Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion].	6.80917e-20
NZ_CP030848.1\|WP_149525619.1\|1889526_1891194_+\|peptide-N-glycosidase	gnl\|CDD\|378122	pfam09112, N-glycanase_N, Peptide-N-glycosidase F, N terminal. Members of this family adopt an eight-stranded antiparallel beta jelly roll configuration, with the beta strands arranged into two sheets. They are similar in topology to many viral capsid proteins, as well as lectins and several glucanases. The domain allows the protein to bind sugars and catalyzes the complete removal of N-linked oligosaccharide chains from glycoproteins.	1.04543e-60

>NZ_CP030848.1|WP_149525610.1|1873364_1873622_-|5-oxoprolinase
MSNTKPLQQHLVEQFNNYSTQELVILNNDIVKSNWGKSKSVFRSALLSALSKRGIDLSEIISKEDGITLIQRVAVRLEANRVIAI
>NZ_CP030848.1|WP_149525478.1|1872000_1872909_-|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVVEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEIMDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSKVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149525609.1|1870883_1871984_+|DUF2891-family-protein
MHIRTTILGLVLISGIFTSCQSETDKKEKTEIEKTHLTATLAKDIFALPTHCLQIEYPNKLGQVIASDADLKTPKALRPVFYGCFDWHSSVHGYWSIVKLMKQFPELDANGEVRQVLNQHITPENVVIEKAFFEDKNNLGFERTYGWAWLFKLQEELHTWNDPDAKRWEQALQPLVDLLVNRYKEYLPKQVYPIRTGQHDNTAFGLSLSLDYARTVGDRSFEAVIKERSLRYFKQDVNCNLAYEPSGNDFLSPCMEEAFLMSKIMDKQEYNAWLKTFMPVLFDKDFKLEPAVVKDRTDGKLVHLDGLNYSRAACLFGIVKQIPELESLKAIAENHIAFSIGNISAKDDYMGSHWLGTFALYALSGS
>NZ_CP030848.1|WP_149525608.1|1870141_1870816_-|DUF937-domain-containing-protein
MNITDLISGNIGSQAVDSISQKLGVDKDKAQYVVAAAVPLMMSALNYNANKSPEQANGIQNAIDSKHNGSIFDNLGALFNQGPTEDEDKIVNHMFGRNTDNVKETLSAKTGLDIKKIAGILALVAPLVMGYLGKKKQESAGETASTGGGIGDLIGSVLGGGGSGAAAGGLGGILGNILGGAGANNSQPNVGGGLGDLVGDFFNQDKDKESKGGILDALTGMFGK
>NZ_CP030848.1|WP_149525607.1|1868893_1869931_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MENKISFKNDYSEGAHPRILEVLSETNLQQEPGYGYDCISEKAKTYIKSHLANQDTPIYFVSGGTQANVLVISHLLKHYESVIATDTGHIHVHETGAIEYAGHKINTVPHINGKLTVEGIQSVLDLHTDEHMVKPALVYISQTTELGSIYSKEELQSISNLCREKGLKLFIDGARMASALCSEKVSLEIRDIAKYADVFYLGATKNGGLLGEAIVFANPELAEGFSYALKQKGALMAKGRLLGAQFYTLFEEQLYFELAKHANRQAMRIAEALQSAGFRFALTPESNQLFPILPYNTINILFEDFEFYVWEKLNEQEAVVRIVCSWATNENDVDLFIRKIKDLSR
>NZ_CP030848.1|WP_149527673.1|1868298_1868826_-|isopentenyl-diphosphate-Delta-isomerase
MKEEYVILVDEQDNAIGEMEKQAAHEENKKHRAFSVFLLDEQGRILLQKRAAGKYHSPNLWTNACCGHPRPDETTIDAAKRRTFEELGIQVEIEELFTLSYAEQLENGLWENEYDHVFVGKYTDPIERFNPDEVRAIKYVAAYELLDDLKLHPEQYTFWFKKIMPKLLPYLEKVD
>NZ_CP030848.1|WP_149525606.1|1866126_1868052_-|FUSC-family-protein
MLFLFWDGHIAVAFAVGTLLASLTDLPGNKADKLTTAAYCIPIFFITAITSSLALHYDSWTIVLLLGIFGFVYTIIALLGFRINVVGNLGLIVASFTIGLRPEDPIQFSLSVTAGAIFFFIVCIAQVYLFPHRSLRYAVEGGISNMAKLIRLKVDCYDEDVPLNKTYKQLSALHSRVSDQLESVRSILLRDKYLLQEGNAYSKRWLGKLYQLVDLYELLMAVDNDYETIRETLRGGKTLHTIRRSLAILAFETARLMQSNKEKTFRSIGTSELNRLFLQLEADQRQSSPEKAALIYSISAQLKQLSDILQNIHVSKFAADDSWIESKNFKDFVAPQSSFQTIVKNLNFRSPIFSYAVRMSILLISGGLIGYLLPEYRYASWILLTIILVARPSYTITQKRNYQRIVGSLIGIAASLLLLVFIKNTLVLLAIAALCLYLFLLFNKPNYLVCVIFITITILLGQKLHEGELHDILGSRFAFTLLGSIFAVLGCLAIPINHYRSVEQTTASLYKHFRDYLDKIEESYQTENLNHYDLRLLRKFTQASLAQSYDSLEQFAKEPLRGKAFKADIQHLQTLAYRINALLVGLSVNINKLGLDWNHDAMNSRVNYVQVLIEEAEELSKKLAQSKRTKDSNNVHFQPSK
>NZ_CP030848.1|WP_149525605.1|1865546_1866050_-|DinB-family-protein
MEINQQISKEITEVFDQLKGIIQDLSDEQINQKPADGGWSIGQIVEHILRSSSGIPDQKVQTYNRAFDEQVPAIRSLFMDLNSKFEADKSLLPRQESYVKDDLLERVLARKTKLVLDIKDKDLTLLCMDMEFPKLGYLTRFEWLTVIATHSKRHCYQIEGVRGNFGY
>NZ_CP030848.1|WP_149525604.1|1865009_1865501_+|GNAT-family-N-acetyltransferase
MISTVLEKKHNRKNFRCGVDELDIYLKQYANQDIKRRLAVCYVIADKNNDVIGYYTLSSNHIDISDILENLAKSLTYSEVPVIIIGRLAVHQDYQGNKLGQALLIDAFKRILEISTLVGNHAVIVDPTNEPAEKFYAKLGFIPLKKSKRMFLPLRTIVDLFEK
>NZ_CP030848.1|WP_149525603.1|1864726_1865041_+|DUF1778-domain-containing-protein
MATSVDRIDIRISKENKDLIKYAAEISGFKTVSEFIVSLAKKEAKRIIEEETKLLKSMEDKIHFVEALLNPPAPNKALKSALEQYNDLFNSAAPNDFDSFRKKA
>NZ_CP030848.1|WP_149525611.1|1874343_1875807_-|RNA-polymerase-factor-sigma-54
MLKQTLQQKLLQKLSPQQIQFIKLLQVPTVSLDARIKEELEENPALEDGSLANMNEPVEEYPDKDPDDDFNAEESNYEDEFSVDEYIQEDDYKDYGGGYDSDDDDNKKEMPIAIQDSFFENLQNQLDLLALSNKDYLIGQQIIGSLDDDGYLRRPIPSLIDDLAFSQNVIVEEKDVEEMLRIIQEFDPAGIGARSLQECLAIQLRKKDQENPIIQKAMQVVENYLEEFTKKHYDKIEKQLGVNSEELRDIVNEILKLNPKPGDSGAAAGKQLHIIPDFHISNNDGVLHLTLNGRNAPELRVSRSYQEMFEHYEKAEKNDKKMREAVQFVKQKLDSAKWFIDAIKQRQQTLLKTMNAIMEYQYEYFLTGDDRMLKPMILKDIADRIEMDISTVSRVANSKYVQTEFGTFLLKSFFSEAIQTESGEEVSNKEVKKILEECIANEDKRKPLADEKLTEILKEKGYSIARRTVAKYREAMNIPVARLRKEL
>NZ_CP030848.1|WP_149525612.1|1876035_1878360_+|penicillin-binding-protein
MFKRVKNKFLRIALIIIYFVILFTCAVQINFLGLFGASPTKKEILLPSLNVSSELYTADSVLIGRYYKQDRDPVPFDSISPNIINALIATEDVRFYKHNGVDVIGLFAGVLSTVGGSDRGASTITQQLAKNLYRTRYKDSQGLLGKIPGVGIIVTKYKEWMTAFKLENKYSKQEIITMYLNTVSFSNNAYGIKSASVRYFDKLPSEISVNEAAVLIGMLKGTTLYNPIRNPKNALSRRNVVLGQMQKEGYLKPEEVKTLSQDSLGLNLNNQEVRNSNDSYLRTAVEKWLEKWAEENEVDIYTSGLKIYTTIDSRMQKIAEDAVALKMKELQRRLDNVWSGQEPWRDKEGNVIPNFLEDQARKLPAYAYLKEKYNDEAKVFEELNRKKEMEVFTWDGMEKVEYSSMDSLKHYISMLNTGMMSMNPYSGEIKVWVGGINHDYYKFDHVNQAKRQPGSTFKPFAYVTALEAGKTPCDKYSDKPVKIEFVNNKGEHEIWEPKNADWNFSYSELSLRHALARSLNSVTAQITEEVGWDNVVKMAHTCGIDSKLESVPSVGLGSNEVSVFEMVRAYSTFMNAGKKTEPILVKRIEDKDGKVLAEFKSEQKQVISPENAWLMGYMLRGTIEESGGTSQALWEWDLFDNENEIGGKTGTSSDYVDGWYMGVTKDLVTGVWVGCDEQSIHFKSSATGEGSKTALPIFAVYMEELYKRPELGVTTGKFPEPIVEIKKTYNCPGPRVRSTRDTPDSGAVEGETEVPALTLPEILQEIQGEEEGQE
>NZ_CP030848.1|WP_149527674.1|1878478_1881529_+|tolB-protein-precursor
MFPQMVNAQYFGQNKMRYKKLDFKVYETPHFNLYYYLKNDSMMNWLAKESEVWYELHQQVFQDTFFRKNPIIFYNNHPEFQQTTAISGEISVGTGGVTEAFKQRVVMPIMQINQQTRHVLGHEMVHAFQYRVLIEGGDSTRLENVANIPLWMVEGMAEYFSIGKKDAFTSMWMRDAYARNDLPSLGQMTQQMNRYFPYRYGQAFWSYIGSTYGDTVIMPLFIETAKYGYEHGIRRVFGYDAQTMSTLWKNSMENTYRNSGKDTTSRPIGQALLTTKNAGRMNVSPAISPDGKYVAFLSELDLFSIDLFLADAQTGKIVRKLGSRLTNKDIDEFSFLESAGTFSPDSKKFAFSVFSEGKNKLMVVDVETGKTLSVEAMGEISEFTNITWAPDGVHVAFSGLSNGHSDIYVYNLQTKVVDQLMDDRFSDFQPSFSRDGKYIVFSTDRVALSSDSRTVDIPMNLAFVEVATKKITNLDVFPGANNLNPHFSSDGKDIYFLSNSDGYRNMYRYTFETQQVARMTDFFTGISGITEYSPAMSISANDDIVYSYFKNNAYSVYKAKATEFEAQPVSAGAVDFEAAMLPPLQARGVNVVNTNLENFNAYSRISDAQINNIPYKPKFKLDYLANSGVGMSVGSRYGAGIASGVQGMFSDILGYNQIFAALNINGEIYDFGGQVAYINQRSRWNWGGSISHIPYRFGFYQYDFRDIGRGTEEPVLDQYLVRSFQTQVDGFVAYPFNKHHRFETGAAASYNSYRVDRYYQTLGNFYYADRERVPTDEASQLLGARLDPFNLFQVNAGFVGDNAVFGIAAPLQGFRYRLGAEQYFGTFNFTAINIDLRKYHRMKPFTLAARVYSYMRVGDGADQLYNIYIGYPYLIRGFESSSFGPSSMVSFNDLSGSKMVVGNLELRLPFTGPEKLAVLPSGLLFSDLNFFIDGGLAWKNGSTIKWTKTDEDRLQDPASGEYYYDPAVRMPVFSAGVSLRVNLFGAMILEPYYAIQLNNPTRSKFGTFGLNFAPGW
>NZ_CP030848.1|WP_149525613.1|1881595_1881919_-|hypothetical-protein
MKTFHLYISTDANRRHLQPGITNDIIGIQQQLQDPTNAGMFSSAVLNRIVYIESFASEREAERRYQELCGLGRMVRERLVRRNNPNWLSLGLPLPGLNPTKKAVVFA
>NZ_CP030848.1|WP_149525614.1|1882034_1882808_+|helix-turn-helix-domain-containing-protein
MSNIASNLKYLRKKKGVTQQQFADLMEIKRASVGAYEEDRAEPKYELLKKIAEFYELSMDELANDVIDDKWKPTPKSNASNLRVLSVTVDADDRENIELVPVKASAGYLNGYGDPEYVKELPKFSLPMFNQGTYRAFEIKGDSMLPLPSGSLIIAEYVENWHDIKTGQTYVIVSSNDGIVYKRIGQKYKEDKGLKLVSDNKTYEPYWVDAGDIIEVWKAKAFISTELPEPSPEPTLEGLSSMMAQMQKTIKAVVDKN
>NZ_CP030848.1|WP_149525615.1|1882924_1883389_+|ribosome-assembly-cofactor-RimP
MQVEERVKELVLEKIADREDLFIVSIRFLKNGVLEILLDGDNGIAIEDCVQVSRHVGYHLEEENVIDRAYRLEVSSPGIDTPLMLSRQYEKNIGRNVKVQMLDGTKREGKLLAAGESSFNLEEVVKEKGKKSQLVEVEIPYDQIKETKVLISFK
>NZ_CP030848.1|WP_149525616.1|1883391_1884630_+|transcription-termination/antitermination-protein-NusA
MSSNINLIDSFQEFKDFKNIDRPTVITVLEEVFRSMIRKRFGTDENVDVIVNPDNGDLEIWRTRVVMEDGFSEDDDLEIELAEAHQYDADLEVGDDYIEQITLESFGRRAILAARQTLVSKILELEKDEVFKKYKDREGELVIGEVYQIWKKEILVLDEDNNELILPKTEQIPADYFKKGDSIRAVVHKVDMMNSNPKIIISRTAPEFLQRLFELEVPEIFDGLITIKKIVREPGERAKVAVESYDDRIDPVGACVGMKGSRIHGIVRELRNENIDVINFTTNNSLYITRALSPARITSIKLDDENKTAAVYLKPDQVSLAIGRGGHNIKLAGKLTGYEIDVYRETGEEEEDVDIEEFADEIDNWIIDELKRVGLDTAKSVLSLTEDELIRRTDLEEDTIREIVRILQAEFE
>NZ_CP030848.1|WP_149525617.1|1884731_1887755_+|translation-initiation-factor-IF-2
MSEGKSINLLKAAKELNIGIGTAVDFLVKKGFDVESKPNTKLSADQYGVLLKEFQGDKNVKDEAKQIVIGKIRREEGPAATQGSTPDEPTEQREDSGDVKEILIKNTTAAPAAETAEDKKAEEHHSALKVVGKIDLDSLRRGAKASPKEEPKEEVAETPKPVVEEKKEVVEPVKKVEEPVAKPVVDQPKVEEKKEPVKEAEQPKVEAPVKEVKQQPVVEKKPEPVKQQPAQQPTKEQPQDEVIRARSETLSGPKVVGKIQLPVSKPHKPVASSSASAGNNNDNKRKRKRTNKGTGPVGQHDGGDRNNQNQNTGQGQHPNQNRPDGNRPRPGGDNRPGGRGGNQQNDRHGNRGGNNRHHDRRKPEVAKEEPTEKEIQDQIKATLARLSGAGKSGKFAQRAKLRRQKRDDIALSAEEAALEQEAMSKVLRVTEFVTANELANLMDVPVTQVIATCMSLGMFVSINQRLDAETLAIVADEFGYQIEFIKPEDEEVAELEEPDTEANLVSRAPIVTVMGHVDHGKTSLLDYIRKANVTKGEAGGITQHIGAYAVKLDDGRKITFLDTPGHEAFTAMRARGAKVTDIVIIVIAADDAVMPQTKEAINHAMAAGSPIVFAFTKVDKPGANADRIREQLSAMNILVEDWGGKYQAQEISAKTGENVELLLEKVLLEAEMLELTADPKKRAVGSVIEAALDKGRGIVTTVLVQGGTLRVGDPILAGSYSGKVKALTNERGERVKEAGPSVPVQILGMAGAPTAGDKLYVLESESEARQVANKRLQLQREQGMRATKHITLDEIGRRLAIGNFKELNIIVKGDVDGSIEALSDSLLKLSTDEIQVNIIHKSVGAISESDVLLASASDAIIIGFQVRPTQGARKLAENEQIDIRLYSIIYDAIEEIKSAMEGMLAPKLEEKIVAEVEIREVFKISKVGTIAGCMVLDGKINRNNDIRIIRDGVVIHTGRLASLKRFKDDVKEVSQGYECGLSIERFNDIQEKDIVEAFEQVEIKRKL
>NZ_CP030848.1|WP_149525618.1|1888474_1889518_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MYNFKISEIVQHPNHNISIRFQDLSNSFPAYKAGQFLTLSFTFGEREVRRSYSFSSSPDVDEPYEITVKRVDNGEISRLLHHQTRVGDVIQVMDPQGLFVYEPDVDHKQTIFLFGAGVGITPLFSILKTALVREEHSKIVLVYSNSSKEQTVFYDELLKWQEAYPDRLHIEWIWSNTKNLLKARLNRDYILELVAKYKSDGEEDVFYTCGPLFYMDLCRFTLLGMGIPDDHIKRETFHFPEEEEDEDEKEEEPVDMTSYDVIIRFQGIDHPLTIPYNKSILDVGLENKLKLPYSCKSGMCSTCISQVTKGSVRMDYNEVLTDREVDNGRCLICTSHPMEDGTTIEVL
>NZ_CP030848.1|WP_149525619.1|1889526_1891194_+|peptide-N-glycosidase
MLNRIVLLFLLSCFIGNVKGQETYKITYHAFRDGAMIKQDPIVLFVSKDKYVITKESIISGQVRYPAEQIFADIKNRKGYRTSLLSEKRSISSYDPGIYNKLEFIQQDTGAKKILRYNTKLAKTSINSNAIEVWYSNALGLNAAPNLIGQDLGLVLEYRRNGNTGIRVAAIEKLKSWPKEFVQPLESTLLGDLSYKDQLWKSRFIQIPIFQDEQICFQPGIQSDSVLRFAEGTVILKKVKIPEITSDSQAFIEVIQKSNGDAYDRTGSVFLIADDQKQTFFDGMQNGMNSLPMYTDEKGAAYPGMVRTEGYSPVLELMRFFTPFGISHFNDRVKLKGKTWQDSVSYRQDISEFTSSLSGKEVYIGTYIGNYDKGGHQVSLELTIHPGGSNYASGVQVMPLFNTTNVMEMGGQGYPTMFAYEKGLEVKFTLDKDLKNVRLRYITTGHGGWGNGDEFVPKANSIYLDGQLKMKFTPWRLDCGSYRLYNPVSGNFENGLSSSDLSRSNWCPGTITSPVFIDLGDLSAGEHTIRVQIPQGPKEGDSQSFWNTSGCLIYE

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Crispr_ID: NZ_CP030848_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_6

2154369-2154459

Orphan

Consensus_repeat	Method
ACCAGGAAAGGAAGGATGCAAGGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_6

>merge|NZ_CP030848|6|2154369-2154459|CRISPRCasFinder
ACCAGGAAAGGAAGGATGCAAGGATTGACAGGATCATGTTGAAAGAAAAAATGGGTCCGTTTCTGAACCAGGAAAGGAAGGATGAAAGGAT

>NZ_CP030848|6|6|2154369-2154459|CRISPRCasFinder
ACCAGGAAAGGAAGGATGCAAGGAT	TGACAGGATCATGTTGAAAGAAAAAATGGGTCCGTTTCTGA
ACCAGGAAAGGAAGGATGAAAGGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149527687.1\|2143993_2145136_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|235596
NZ_CP030848.1\|WP_149527689.1\|2154633_2154963_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	unknown	unknown	gnl\|CDD\|238042
NZ_CP030848.1\|WP_149525830.1\|2157255_2158116_+\|TIM-barrel-protein	unknown	unknown	gnl\|CDD\|224007
NZ_CP030848.1\|WP_149525824.1\|2147444_2147939_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|379209
NZ_CP030848.1\|WP_149525829.1\|2155522_2156137_+\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|319973
NZ_CP030848.1\|WP_149525832.1\|2161649_2162531_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|366370
NZ_CP030848.1\|WP_149525835.1\|2163930_2164305_-\|methylglyoxal-synthase	unknown	unknown	gnl\|CDD\|179969
NZ_CP030848.1\|WP_149525831.1\|2158928_2160266_+\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|238080
NZ_CP030848.1\|WP_149525822.1\|2142661_2143030_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|376503
NZ_CP030848.1\|WP_149524797.1\|2153141_2154050_-\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525828.1\|2155045_2155504_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527688.1\|2145343_2146330_+\|bile-acid:sodium-symporter	unknown	unknown	gnl\|CDD\|372642
NZ_CP030848.1\|WP_149525826.1\|2148239_2148896_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187560
NZ_CP030848.1\|WP_149525834.1\|2163513_2163927_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|376823
NZ_CP030848.1\|WP_149525823.1\|2146382_2147363_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP030848.1\|WP_149525833.1\|2162517_2163462_-\|type-I-pantothenate-kinase	unknown	unknown	gnl\|CDD\|235466
NZ_CP030848.1\|WP_149526414.1\|2151438_2152887_+\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|377531
NZ_CP030848.1\|WP_149525827.1\|2149092_2151306_+\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|377178
NZ_CP030848.1\|WP_149527690.1\|2160505_2161459_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_CP030848.1\|WP_149525825.1\|2147948_2148230_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149527687.1\|2143993_2145136_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NZ_CP030848.1\|WP_149527689.1\|2154633_2154963_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	5.17205e-15
NZ_CP030848.1\|WP_149525830.1\|2157255_2158116_+\|TIM-barrel-protein	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	2.59684e-23
NZ_CP030848.1\|WP_149525824.1\|2147444_2147939_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	4.95861e-36
NZ_CP030848.1\|WP_149525829.1\|2155522_2156137_+\|protein-tyrosine-phosphatase	gnl\|CDD\|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	1.39418e-11
NZ_CP030848.1\|WP_149525832.1\|2161649_2162531_+\|mechanosensitive-ion-channel	gnl\|CDD\|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	1.49523e-22
NZ_CP030848.1\|WP_149525835.1\|2163930_2164305_-\|methylglyoxal-synthase	gnl\|CDD\|179969	PRK05234, mgsA, methylglyoxal synthase; Validated.	2.45834e-65
NZ_CP030848.1\|WP_149525831.1\|2158928_2160266_+\|PDZ-domain-containing-protein	gnl\|CDD\|238080	cd00136, PDZ, PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. Heterodimerization through PDZ-PDZ domain interactions adds to the domain's versatility, and PDZ domain-mediated interactions may be modulated dynamically through target phosphorylation. Some PDZ domains play a role in scaffolding supramolecular complexes. PDZ domains are found in diverse signaling proteins in bacteria, archebacteria, and eurkayotes. This CD contains two distinct structural subgroups with either a N- or C-terminal beta-strand forming the peptide-binding groove base. The circular permutation placing the strand on the N-terminus appears to be found in Eumetazoa only, while the C-terminal variant is found in all three kingdoms of life, and seems to co-occur with protease domains. PDZ domains have been named after PSD95(post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1, a mammalian tight junction protein.	1.60507e-10
NZ_CP030848.1\|WP_149525822.1\|2142661_2143030_-\|30S-ribosomal-protein-S6	gnl\|CDD\|376503	pfam01250, Ribosomal_S6, Ribosomal protein S6.	6.07537e-36
NZ_CP030848.1\|WP_149527688.1\|2145343_2146330_+\|bile-acid:sodium-symporter	gnl\|CDD\|372642	pfam13593, SBF_like, SBF-like CPA transporter family (DUF4137). These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.	6.88406e-92
NZ_CP030848.1\|WP_149525826.1\|2148239_2148896_+\|NAD(P)H-binding-protein	gnl\|CDD\|187560	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs. Atypical SDRs in this subgroup include CC3 (also known as TIP30) which is implicated in tumor suppression. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine rich NAD(P)-binding motif that resembles the extended SDRs, and have an active site triad of the SDRs (YXXXK and upstream Ser), although the upstream Asn of the usual SDR active site is substituted with Asp. For CC3, the Tyr of the triad is displaced compared to the usual SDRs and the protein is monomeric, both these observations suggest that the usual SDR catalytic activity is not present. NADP appears to serve an important role as a ligand, and may be important in the interaction with other macromolecules. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.12879e-65
NZ_CP030848.1\|WP_149525834.1\|2163513_2163927_-\|OsmC-family-protein	gnl\|CDD\|376823	pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.	6.04934e-22
NZ_CP030848.1\|WP_149525823.1\|2146382_2147363_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.1428e-70
NZ_CP030848.1\|WP_149525833.1\|2162517_2163462_-\|type-I-pantothenate-kinase	gnl\|CDD\|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	3.13123e-178
NZ_CP030848.1\|WP_149526414.1\|2151438_2152887_+\|IS1182-family-transposase	gnl\|CDD\|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	7.19526e-13
NZ_CP030848.1\|WP_149525827.1\|2149092_2151306_+\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|377178	pfam03971, IDH, Monomeric isocitrate dehydrogenase. NADP(+)-dependent isocitrate dehydrogenase (ICD) is an important enzyme of the intermediary metabolism, as it controls the carbon flux within the citric acid cycle and supplies the cell with 2-oxoglutarate EC:1.1.1.42 and NADPH for biosynthetic purposes.	0
NZ_CP030848.1\|WP_149527690.1\|2160505_2161459_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_CP030848.1\|WP_149525825.1\|2147948_2148230_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	3.43551e-26

>NZ_CP030848.1|WP_149524797.1|2153141_2154050_-|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVIEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSRVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149526414.1|2151438_2152887_+|IS1182-family-transposase
MLSTQQKIQFSSYSGLYDIIVPKDNLLRKINDLIDFSFIYDELLAKYCQTNGRTAESPIKMFKYLLLKTIYTVSDVDVVERSRYDMSFKYFLEMAPEEDVINSSSLTKFRKLRLKDMDLLNLLINRTVTIALEKGIIKSKSIIVDATHTVSRSNPHTALAVLRERSKLLRKAIYQIDGEYKRNLPQKNESNDLDQELAYCRELQRVLDEDQSISEIPAVKEKLNLLKETIEDTKEYYLLSKDDEARLGHKSVDGSFFGYKTHLAMTEERIITAAVVTTGEKGDGPELPRLLEISQQNGMQVDTIIGDAAYSGKENLQLAKEQNIDIIAKLNPSITQGFRKDKDKFDYNKDADMFVCPAGHLAIRKARQGKKEQGTNQTETYYFDVEKCKVCPLREGCYKQGARTKSYSVSIKSELHRDQMAFQQTDYYRSKSKQRYKIEAKNSELKNVHGYGRADAYGIHNMEMQGAMAIFTVNLKRILKLI
>NZ_CP030848.1|WP_149525827.1|2149092_2151306_+|NADP-dependent-isocitrate-dehydrogenase
MSSKIIYTKTDEAPLLATYSFLPIVQAFAKPANIEIELRDISLAGRILANFNDYLSADQKTNDALAELGQLATQPEANIIKLPNISASIPQLKAAIAELQKAGYAIPNYPDAPANAEEEKIKASYAKVLGSAVNPVLREGNSDRRAPKAVKNYAKANPHRMGAWASDSKTKVASMQDGDFYSTEKSVTVENDSQYKIEFVGADGSVKELKGLGNLKAGEVIDSSVLNIAKLQSFVADAIAEAKAAGVLLSAHLKATMMKVSDPIIFGAIVEVYFKDVFAKYGELFAELGINKNNGLGEVYAKIAGNAKEAEVKAAIDAAIANGPDLAMVNSDKGITNLHVPSDVIVDASMPAMIRIGGKMWDKNGAEQDTLALIPDRSYAGIYEAVIDDCKANGAYDPKTMGSVPNVGLMAQKAEEYGSHDKTFQAAANGTIRVVDASGNVYMEQAVETGDIFRMCQTKDAPIQDWVKLAVNRARLSDTPAVFWLDENRAHDREIIKKVKAYLANHDTDGLDIRILSPIEATKFSVERIRQGLDTISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVEQFLEEGYLRWDSLGEFLALQASLEHLSQTQNNPKAQVLADALDEANAKFLANDKSPARKVGQIDNRGSHFYLALYWAEALAAQTKDAELAKAFSELANALSSNEAKINEELIAAQGKAQNIEGYYFPNDELASKAMRPSATLNEAIDKF
>NZ_CP030848.1|WP_149525826.1|2148239_2148896_+|NAD(P)H-binding-protein
MGIKAVIIGGSGATGKELIDQLLERPEVERVTVLLRRPYFKSHKKLNEVIVDFNMLAQYSEHIEGDIAFSTLGTTIRDAGSQEAQWKVDHDYPLTFAEIAKQNGVNTFVLLSSMQADPNAKLFYPRMKGTLEQAIYKLNFPSYMILRPAIIDRPNTDRAGEKAAVGIINFLNKIGLFRRFRAIQTKDLAKALITASIDFPKTGEQLYESKEILNGIKR
>NZ_CP030848.1|WP_149525825.1|2147948_2148230_+|GNAT-family-N-acetyltransferase
MLVKHEVDGNKGGFYAIEEGKKIGEMTYSAAGPGKIIIDHTEVDPEEKGKGIGHVLLMKAVEYARDNNVKILPLCPFAKASFDRDVTIRDVLF
>NZ_CP030848.1|WP_149525824.1|2147444_2147939_+|nuclear-transport-factor-2-family-protein
MKQILLTIMLAVFSISLFAQTKKEEVAKVMDSWHQAAAKADFKAYFDLMDEESIFIGTDATERWDKPAFMAYAKPHFDKGKAWNFTPLERHINFSKNGKTAWLDELLDTQMKICRGSAVLELKNGKWSIKHYVLSMTVPNDVSHVVIKTKAAIEDKVIQSIKHK
>NZ_CP030848.1|WP_149525823.1|2146382_2147363_+|cation-diffusion-facilitator-family-transporter
MSRQMRLVLLSLVTGIVLMLIKFVAYFITESNAIFSDAAESIVNIAASGFAYYSIYLAAQPKDENHPYGHGKVEFFSVFVEGALIFIAGSVILVKAFYNIFFPQPVANVEEGMLLIFITSLINFGVGFYLMKRGRALRSLTIEADGKHLQVDAYSSIGLIAGLFIMKLTKLPWIDLALSIALGCFILYNGYKLLRKSISGLMDESDQEVVDEVVAILKEKRKPEWIDVHNLRVQRYGQELHIDCHLTLPNYYELTTVHDCISEFDNLLNENLESKTEFFIHADPCMPECCHYCAVENCPIRSEEFRKHIEWTTVNVTKNMKHFRKA
>NZ_CP030848.1|WP_149527688.1|2145343_2146330_+|bile-acid:sodium-symporter
MKLKFDGFIVALIAMIILAYIYPDLVQAQNGQLFETISTIGVSLIFFFYGLKLSFREIKDGLKNWKLHVCIQLFTFALFPLIILLFRPFIQNAIQEQFWLSFYFLAALPSTVSSSVVMVSIARGNVPAAIFNASISGLIGVLVTPLLMQSFIQFEQVSVLGDVYWGLIKEIIIPVILGLLLQPYLGKWASKYSKQLSKFDKAVILSIVYSSFAESFLSDVFHKVGTIYLSALFIAVIVFFFLVYGIVYLITLYVLKFNREDQITALFCGSKKSLTHGSVFSKFLFAGNPNLGLYFLPLMVFHAFQIFVVTIIAQRYANQYNEEILTKK
>NZ_CP030848.1|WP_149527687.1|2143993_2145136_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MTKLGRELAAKGINVISLSVGEPDFNTPNHVKEAAKKALDENYTRYSPVPGYPELRQAIVNKLKNENGLDYDISQIVVSTGAKQSLSNVILTLVNPGDEVIIPTPYWVSYSEMVTLAEGKAVYIDTEIESDFKITPAQLEAAITPKSKVFMFSSPCNPTGSVYTKDELAALVAVFEKHPNIFIISDEIYEHINFGDQHESIAQFDSIKDRVIIVNGFSKAFAMTGWRLGYIAANKEIAAANDKMQGQTTSGTCSIAQRAGIVAYEQGLESVLEMKEAFARRRQLVYDLLNDIPGVKTNLPQGAFYFFPEISSFFGKKDPEGNEIKNSADLALYLLNYGHVATVGGDSFGNNNYIRLSYAASDENLKEALRRIKEALGKLA
>NZ_CP030848.1|WP_149525822.1|2142661_2143030_-|30S-ribosomal-protein-S6
MQQYESVIILTPLLSEDAAKEVITKFKSILTEGGAEIIAEDNWGLKKLAYPIQKKTTGFYHLTEFKAPGELIKKLEVEYKRDERVMRFLTISLDKHALAYNEKKRSGAFNKKTEPKAEEVAN
>NZ_CP030848.1|WP_149527689.1|2154633_2154963_+|metalloregulator-ArsR/SmtB-family-transcription-factor
MGVTKTEIYKDEQNKLASLLKVLGHPARIAILQHIINQKACICNDLVEELGLAQATISQHLKELKSIGIIQGSIEGKSVCYCIDEHVWKDFQKEFNVFFNQEVKVNRCC
>NZ_CP030848.1|WP_149525828.1|2155045_2155504_+|hypothetical-protein
MIRNQKILPSLENVEFQLENGTFVPEHFHVTEVGFILKRFIDCGGKIREERIINFQLWDANDFEHRLKPEKLLKIIELSETKLGIEDAEVEVEYQGETIGKYDLNFEDKRFILMNKQTACLAEDACGIPLEKQKVKLKELKNSCCTPNSGCC
>NZ_CP030848.1|WP_149525829.1|2155522_2156137_+|protein-tyrosine-phosphatase
MYIELSETIVKEIDFQNISEDRKLILRPLIDFIQQKIAHKKVANINFICTHNSRRSHLAQIWAQVASAYFKIPNIYCYSGGTEATALFPKVAETLSEQGFKVFGITQSDNPVYSIKFSDNSLPIIGFSKAYDNPFNPTSEFVAVLTCSQADEGCPFIIGAEKRIPIRYEDPKVSDGTPEQSVVYMKRSLQIASEMFYVFSKISP
>NZ_CP030848.1|WP_149525830.1|2157255_2158116_+|TIM-barrel-protein
MKNKSASRRQFLQQSFLAGTALITAPSLFNNTAHAEEQSTVNKQDSLKLGIAGYSFVHFNLEQSLAMMKRMDVRYLCIKDFHLPFDSSAEQIAAFHKKLADANVKGYAVGPIYTKTTQDIDKAFDYAKRVGVDLIVGIPEIKDLPYVSQKCKETNIRYAIHNHGPEDKIYPNATVIWNNIKSLDKNVGMCFDMGHNMRDGQDPLKDLLRYKDRIFDLHLKNVTSATAEGKTCELGRGVINIPAFVKGLQKIKYSGSCSLEFEKDMKDPLAGLAESVGYFRGVLSAI
>NZ_CP030848.1|WP_149525831.1|2158928_2160266_+|PDZ-domain-containing-protein
MRLIALLCMCFMSFYAHGQSEFSFLTKKRHVDFELVGNLIIVPVKLNGVPLSFLLDTGVKETILFAGKQDSVPLDNVHRVKFSGIGIEDGVEGIMAIANDLEIGGTLRDSSHNVFVINGEELDISSHIGMPVNGILGARFIQQFMLKIDYIKSRISLYDPQDFPEKIIRKFTRVPIHLERDRPYTEVDIRLADDRMEHAKMLIDMGNSDGLLIFPFVLDSFQVKEPNVYEFIGRGFNGEIYGKRNRIAGFDWAGFQIKQPIVSYPDSNAVHAARLAESRIGSVGSQVLRHFHVILNYQAEEIYLRPNKNFGKRFEFNMSGMEIKHDGLVWAQREVPTSIGSRSKDDPHGGVTAWQSQILKYEFKLLPVYVVAGVRKDSPAERAGVLKDDVLIKINGKKTENMKLKDVLHKLQHKDGDLINLIVERAGEQRQLQFKLVDPIPYKGN
>NZ_CP030848.1|WP_149527690.1|2160505_2161459_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
METTFDFEKPIADLQTQIEKVKQVEEKTKVDMGATIRELEEKLEQTKLEVYNNMTGWQKVQMSRHADRPQTFDYIDLICDDFIELHGDRTVKDDKAIVGGFASIAGQPVMVIGHQKGKNTKERQFRNFGMANPEGYRKALRLMKMAEKFNKPIVTLIDTMGAYPGLEAEERGQGEAIARNLLEMSVLKVPVICIVIGEGASGGALGIGIGDRVYMLQNTWYSVISPESCSSILWRSWDHKERAAEALKLTAEDMLGNGLIDGIIAEPLGGAHQDPETTAINVKNRILEDLAVLLQKDKDPLVAERIDKFSKMGVVNE
>NZ_CP030848.1|WP_149525832.1|2161649_2162531_+|mechanosensitive-ion-channel
MIAKAEDNKPRFPYVFLLKVFLVIGLIAADTYLAAEIAQRTKLVQVMRGLYSFLIPSIFLSVIRYIVIFLYNARHKQRAVRGNFVLGVNRLTAVLNVVFALIALLISFGINPKDFITSLTIVAMAIAVLFRDYITNMISGLIVMFSEQLSVGDRIKVGEQRGRIVDITFANIVLQDEEDDIIMVPNNLVFTSTFMNLSAHQSSLFTVRFELPLQASLEVEELEEALRVSLTTHPNLSDKPEDFQLKVIELGKDFVRYKLDLHAVSNSNRMHRQLENEILKEVIKFERKVLKSS
>NZ_CP030848.1|WP_149525833.1|2162517_2163462_-|type-I-pantothenate-kinase
MPFISEHTFTSPFQNFTREEWKRLNGQLSNMLAEEDLGALHALNEPLTMEEIEDIYIPLAHLLDVHITGFRELHRQSNDFFRRNNSKLPFIIGIAGSVAVGKSTTARVLRKVLSLLPNKPKVELVTTDGFLYPNKELIRRDILNRKGFPESYNTKELLQFLSDVKSGKSSLTVPIYSHLEYDVLPQDKITIAQPDILIVEGINVLQVNSRKNGVFVSDFFDYSIYVDADEKNIVAWYIDRFESLRATAFQNEKSYFHKYANMSVEESVEMATQIWNEINRPNLHENILPTRYRADLILKKGSHHFVKRVKVRKI
>NZ_CP030848.1|WP_149525834.1|2163513_2163927_-|OsmC-family-protein
MANEVQVTIEEENYTTKVAYGDLSILADEPLDLGGQNKGLTPSQLLLASIGSCKVITMRMYANRKQWDVKKINIDLSSEVVKSDLQQTTYVRCHITFEGNLDEDQVKRLYVIADKCPIHKMLQNPIVIESNVIDTTK
>NZ_CP030848.1|WP_149525835.1|2163930_2164305_-|methylglyoxal-synthase
MAKTIALIAHDGKKAEMVAFVKDHLEELAKAHLVATGTTGSYIQQTGLEVELKLSGPKGGDAQIAAMAAEGKINGIIFFRDPLGKHPHEPDIQMLMRICDLWNVPLATNPATGSLIIKGLLEYQ

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Crispr_ID: NZ_CP030848_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_7

2181468-2181574

Orphan

Consensus_repeat	Method
ATCCTTCCTTTCCTGGTTCAAAGACAAAACATCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_7

>merge|NZ_CP030848|7|2181468-2181574|CRISPRCasFinder
ATCCTTCCTTTCCTGGTTCAAAGACAAAACATCCCGCTCATCTTATCAGACAAAATAACCTGCTCATCCTTTTATCCTTCCTTTCCTGGTTCAAGACAAAACATCCT

>NZ_CP030848|7|7|2181468-2181574|CRISPRCasFinder
ATCCTTCCTTTCCTGGTTCAAAGACAAAACATCC	CGCTCATCTTATCAGACAAAATAACCTGCTCATCCTTTT
ATCCTTCCTTTCCTGGTTCAAGACAAAACATCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525850.1\|2180402_2181281_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525857.1\|2189602_2189725_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP030848.1\|WP_149525841.1\|2169666_2170119_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525854.1\|2185199_2187401_-\|bifunctional-alpha,alpha-trehalose-phosphate-synthase-(UDP-forming)/trehalose-phosphatase	unknown	unknown	gnl\|CDD\|184712
NZ_CP030848.1\|WP_149525844.1\|2172894_2173881_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525860.1\|2193004_2194441_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133045
NZ_CP030848.1\|WP_149525843.1\|2172052_2172991_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525858.1\|2189733_2191296_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_CP030848.1\|WP_149525859.1\|2191825_2192986_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP030848.1\|WP_149525845.1\|2173817_2174213_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525846.1\|2174219_2175809_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525847.1\|2176096_2176633_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525855.1\|2187693_2188530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525848.1\|2176614_2177166_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525856.1\|2188646_2189606_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP030848.1\|WP_149525853.1\|2183389_2185183_-\|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl\|CDD\|225922
NZ_CP030848.1\|WP_149525852.1\|2182531_2183332_-\|DUF4382-domain-containing-protein	unknown	unknown	gnl\|CDD\|379555
NZ_CP030848.1\|WP_149525849.1\|2177340_2178030_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525842.1\|2171886_2172090_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525851.1\|2181671_2182439_+\|DUF3050-domain-containing-protein	unknown	unknown	gnl\|CDD\|378614

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525859.1\|2191825_2192986_+\|hypothetical-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	7.73654e-06
NZ_CP030848.1\|WP_149525860.1\|2193004_2194441_+\|glycosyltransferase	gnl\|CDD\|133045	cd06423, CESA_like, CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.	2.56114e-51
NZ_CP030848.1\|WP_149525858.1\|2189733_2191296_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	6.8165e-10
NZ_CP030848.1\|WP_149525857.1\|2189602_2189725_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	7.57597e-08
NZ_CP030848.1\|WP_149525854.1\|2185199_2187401_-\|bifunctional-alpha,alpha-trehalose-phosphate-synthase-(UDP-forming)/trehalose-phosphatase	gnl\|CDD\|184712	PRK14501, PRK14501, putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional.	0
NZ_CP030848.1\|WP_149525853.1\|2183389_2185183_-\|glycoside-hydrolase-family-15-protein	gnl\|CDD\|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	4.36954e-81
NZ_CP030848.1\|WP_149525852.1\|2182531_2183332_-\|DUF4382-domain-containing-protein	gnl\|CDD\|379555	pfam14321, DUF4382, Domain of unknown function (DUF4382). This family is found in bacteria and archaea, and is typically between 142 and 161 amino acids in length.	2.05076e-34
NZ_CP030848.1\|WP_149525856.1\|2188646_2189606_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	0.00530834
NZ_CP030848.1\|WP_149525851.1\|2181671_2182439_+\|DUF3050-domain-containing-protein	gnl\|CDD\|378614	pfam11251, DUF3050, Protein of unknown function (DUF3050). This bacterial family of proteins has no known function.	1.06665e-133

>NZ_CP030848.1|WP_149525850.1|2180402_2181281_-|hypothetical-protein
MKSERLILVKMWYVRKQDFDIFAKEIHLVSMKKIHIVFTLILLFQGLFLGAQENRANKIELSQQEKEAMFFQKLCFSQTIFPIYEDIFGLDAEPISWITIYWPENKFGFLESKTITISNEQGGEIVFSDDQQHSVSIRGSLMGNSQVVDDKGNWLNFKRNFVGKITIDGEDGQKSSISKNLSNKTKITTHSGQQITIKNTRIGLEISDNRGNNALIEIDSWGNRTLYYPNEDYIAFEYIDAGYQISSNFINDIYIKADSDRGNLEVQEGSTPPYRIINEFRKPLPPDDPFGF
>NZ_CP030848.1|WP_149525849.1|2177340_2178030_-|hypothetical-protein
MKRLLTLISILLIVNAGFSQVAVISSPDGSANIREKPDSKSKVIAKVKTNTVILAFNDEIGVSANDAVWSEVVVIKEPMSRLNTANEEYTYRYSHTSQYKLFDQLKNADPKVFKFEYKHKPFSKSGKKIGYIDGSESIETINGEHYFGADCGTPKTEITKATATIGNKIVDIPMSLIWGILHAGNEFEIKTYNNHYYVSQGVGDGGCFTHLVWVFDKNGLVQRFVGWQY
>NZ_CP030848.1|WP_149525848.1|2176614_2177166_+|hypothetical-protein
MAQSEVTSITEVAGEPYLSGRFASNAHMFNDEWALAIAGPNTYADYINAINKDVYVLGHANYNSSSDAAVVWKNRKEVFKLPLGDFASDVLGTMVGTDYYFVANFYNGGKGTSVVYKNKTKLYQLSGAASITATAIRVVSGKVYILGNYLNGAKSSAVLWTNGKPKVLFGEGKKIYLNDFAVN
>NZ_CP030848.1|WP_149525847.1|2176096_2176633_+|hypothetical-protein
MRKLNFKSVIVACSLLAVISACSKKSIEPVEPDPENPETPTPKPPTPKPLTFFYAGYKYQTDYKGAGRNAILSINDSIVLLSPSLRSDALAIAAVNNKEAHVTGYQKTSSGQQRVAYWKNGKISFLTQAGNNNTGTAINVIGSKVYVGGTKITMEHMVYFFGQMASRRERHAVWHSQK
>NZ_CP030848.1|WP_149525846.1|2174219_2175809_-|hypothetical-protein
MNNDVFKIMEDLKWKAVGVDPSTGQTPNNQFVSFLPIGLPIPEEDFKNPWTPTQSNLTEAVKSARENKARTTDATDPANTDAASASSALEDILLTSGSIGQSMNAYLQTFSLTDTKISIDDTYRAWPNAAKVNDTWFAIINGANGLESGLEANDAIKAALERAEKLMVDEEGNDTPKYEKYNQYRDEYYDAVRERDRQYANALSDPLKFNLWPMQGKIYQDDVDYAWDKWQSRGAKQEIEEAMALLSAQGIDPAILMIRRAKIKYENSLINMPGIGNLPYTFITPSKWYSKNGPGWNTYSQTDYHSKKTFDTLSTKKDMSARISSGFRLFGSLGGSVNHSSAHSEKHISSSFEGLTITFSYCLANINRPWMDSSLMNIGNWFLMGNYPEGCISTAKVDQEFKPDDPKQFVLLPSVVTSMILIKDVLISWSSASFDSNEITDTLKNGGSVSFGNLFVSGSGSASYRKDKYHWDQTIDQNTRQLRVDGVQLIGFVSSIMPFAPKLNGANYTQKKKEEPKKEEPVKEEENNG
>NZ_CP030848.1|WP_149525845.1|2173817_2174213_-|hypothetical-protein
MDFQAKLQEFFLSQFKDGLEESKLFIAFEPIGCMIDELDPNDPQSQTRANEQLSILAERLPAIQESMTFGTSRLTDLLETLVYSSTFREDLLMMPKEKITERSSVVRRRKRWGNLKKEKERPSSQHQVPIS
>NZ_CP030848.1|WP_149525844.1|2172894_2173881_-|hypothetical-protein
MGKLEKGKRASVVTASGSYFLVTGHPEAWYNKNAAIWTSKSFSQKFPEKADEQDKPISFNLKWNRIDQSRLTTAVETKFEGIVTHKGIFNNMLFHEQKVKKPLNHKFLRTKRLQMGSQAINLQAKPMLSSEINPTMVKPLLSKRIALTHQLHKEKLVVQEQSQADGYELSFDYCMVNLQRDWFDRSLLHYAKLWYAKALEKNFFSNGLKDSSNQGELKCITTAMILVKNLRIRANWSQQDIANAGDSISLGFFNVADSQINSKNELINPGIQALGWICEVMPALPYSSDPKLLNNRSWKISVLKSQNSPVAVLTRAPFLVNRICLMVV
>NZ_CP030848.1|WP_149525843.1|2172052_2172991_-|hypothetical-protein
MENFSTKIAELARRGFDTGAILSESNLPNGRVAICQNCVLYACPDELIFEVHGNILMKYQEVGETNSSLGYPRSDEMDDPCVAGGKVSYFEYGKISWQYPNGSQIEMYEFVDLDSYEQQRAPLVAKLQEIADYAFEALSEPQSSIENRIKKGSEESWCGKAVAYFYAQAGVPSRTTSQFMNTRNISLFGSYGKIAFDGSGVLRKDYPENTQLKEQHSAQDAARKMITFEDIEAEYELDILPGDIVLVDNSDKGGADHIQIVYKYNPETRMLTVVDGNGGGFALASLGIPNNDSALAQTAADGTPISAKKTMD
>NZ_CP030848.1|WP_149525842.1|2171886_2172090_-|hypothetical-protein
MAPQYPQKKQWIEDDLGVSLIYQGNVAGHVGISCHILMPEYQVRYEDNKVKHKRVWAIVRPSILDLQ
>NZ_CP030848.1|WP_149525841.1|2169666_2170119_+|hypothetical-protein
MYTDETNLSLLISLLSEERDRLQILIDQAISDHEYLSAHYHAVALEKVSLSLYKLRNIEDPLYSEKEFWKRTIELLKKDIESEGSSDMLEYYESCILNAREELEKLSQEVRQPSHNESRQFAAVLEQLLDKKVKNLKLFLDKTDKFYYSH
>NZ_CP030848.1|WP_149525851.1|2181671_2182439_+|DUF3050-domain-containing-protein
MQNRINTIHSFISEERAILLSHPLYQKIKTVEDLRKFTEGHVYAVWDFMSLLKALQIQLTCTQVPWFASEYPDTRYLINEIVLAEESDEYFDGRRLSHFEMYLDSMQALGANCEPIQSFVAGLNGISDIHAAIDAQSFDPRIKDFLHFTFDCIASQEPHKVASAFTFGREDLIPDMFSSILDSLKLQFPDTDLDRLIYYFQRHIELDGDEHGPLAMRMIMELAGEDEKKWEEMQLTAKQALQKRIALWDAIEASL
>NZ_CP030848.1|WP_149525852.1|2182531_2183332_-|DUF4382-domain-containing-protein
MQYSDITMKNTLFFSLALATLAFGSCSTDDGIPTGKTPVTIKMTDAPANYDAIYLNIDEIEIRTVSGAEVIDVDADPFDILQYRFGRDTVIAAHDVPSGRIQEIRLKLEDEGNEIVVDGQRYPLTTPSGQSSGVKLKVHDDLIPNVAYTLLIDFDAAKSVHQTGNGKWMLKPVLRAIPVATSGAIEGVVAPFSAWPNVYAITGTDTIGTITNPLGKFYFPGVDQGTYKLVIEPTEPGYDTVSQDVIVTQGKVTNVGTINLGTVSEN
>NZ_CP030848.1|WP_149525853.1|2183389_2185183_-|glycoside-hydrolase-family-15-protein
MNKKHLYNSGIIGNCNFIAHVHKSTNINWLCWPTFRDSFVFGCLLDKNKGGEFNIRLQGDNVYSKQYYLENTNILVTEVHSDQGSFKVTDFAPRFEQYERFYKPLMLIRIVEPLEGNPKIKVTCNPKANYGLADFHRSRGSNHVQFNYDNEHMRLTTNIPISHFFDEDKSSIILSEKKYMVLNYGSAFEAALEKTVEDFLIRTKQYWRNWTKKADVPNFYQDQIIRSALVLKLHQYEDTGAIIASSTTSLPESPGSGRNWDYRYCWVRDSYYVLTALANIGKFDELEKFATYITGITQSDSGRLQPLYGILGRRTLTEETLDYLEGYLGNKPVRIGNQAYEHIQNDVYGQAMIALLPLFTDFRFPADERKDAKSWLVYILDKIATTIDEKDAGIWEFRHIANRHAYSNLFQWAGASAALKIAKQNGYQDIEIQAQELKDKAAAHIESCYDEERKVYRNASEGSDLDASTLQLIMMHYLDPNSERAKLHLNELEKVLKGKNGLFYRYLHQDDFGKPQSTFLVCAFWYVEALACVGRIDEAQEIFHNLMGYSNHLGLFSEDVHEEDGSQWGNFPQAYSHVGLMNAAYRIATKLDRPIFT
>NZ_CP030848.1|WP_149525854.1|2185199_2187401_-|bifunctional-alpha,alpha-trehalose-phosphate-synthase-(UDP-forming)/trehalose-phosphatase
MRNQTPTNSGKTLIISNRLPVKIERKKGKLKFTASEGGLATGLGSFYKDNGSWWIGWPGIIPKTEEEEQHIREELYKLNLIPVFLTQTEIKNYYEGFSNAVLWPLCHYRPSYVELRDDYWDAYEQVNEKFAKASLPYIEAETTVWVHDYQLMLLPKYIREQSQPSSIGYFHHIPFPPPELFSMLPWRKQLLDGLSSADLVGFHTYENAHNFLEANQTLLNAEIHHHHIKLEGRSCFVDVFPMGIDYEKYKRQAIDKKTQLYAAELKKLFEDKKIILSVDRLDYSKGILQRLASYEKLLLKYPELQEKVVLYMLIVPSRDQVNQYKKLRNEIDRKVGNINAVLGSPGWQPVSYFYKSLPFDKLSAVYAAADVCLVSSLYDGMNLVAKEYIASKQLQTGALVLSEFAGASKELSDALLINPYAIEDSSDILYEALMMSESEKQERMQASQQVVEKFNVFHWVNLFFQRLREIKEQQNKAITRKVKDQVRTSIKSTYKQATNRLILLDYDGTLVGFNKDAAKATPTAELHQLLENIANDKQNTLSLVSGRKYDNMQDWFPDKSFFTIAEHGIWSNFPNHQWHIKEGLSNEWKVFVRSILQRFTDRTPGSLIEEKTYSLAWHYRKVDHALGKIKAQELLQELHPLANEIGLQIINGDRVIEIKNMEINKGKAVVQLVNEINPDYILCIGDDATDEDMFNELPANAVTIKVGNKQSAAKYFVENKEEVLQLLTELTQL
>NZ_CP030848.1|WP_149525855.1|2187693_2188530_+|hypothetical-protein
MLNRAIKRYGLFGLIIGLFFSILCIHVILILNVIILPIPLVYGPLLFFIFKASLQERVDAGTVLLHLTPLISFLILFLLDPTGWYPEVHVPYMLTVFCLLTGYPVYILFKSSKLKSETAEVNKILFVENLALLGVAAAFFFGLLFFNEVMHLDFDVNPLFVVIALMIISMGLIVWYIYTSRVDKKKEALPLVDELVHLNLARETIEFYKEKLNSIMEGEQLFLDANLSLEGLSVYANIPKHHISYIINTSLESNFYEWLAKYRIAYSIQLLNSGTDNL
>NZ_CP030848.1|WP_149525856.1|2188646_2189606_+|helix-turn-helix-transcriptional-regulator
MIFTFLYCATSITCLLGLQVSYYVNHKTVMDRLAQFFLLTLLIHICHAAIFRDLLPGLIYVDRSAPFGLMYGPFLYFAYRAIEQKAITAKQVLLHGLPFLIGLIGHFVFISSYSFRMEYRSEYYLVLYSLMGLSWFFYPVGVFIISNNGANRARLERRIYYYSVILILVSSIFMLTLVLNRMMEKGSADAPSSGATIFFIMLLGSLLGYNYLLGRLRKPLRLEMQSFTGDLNVDPFERNLTGLTYAEQQGIKLKIIDYLVEKSYLDTEFSIDKMSKLLNVSKPVIQQFFKLHFNDSFLKVINALRIKEACIYLSDEALI
>NZ_CP030848.1|WP_149525857.1|2189602_2189725_+|AraC-family-transcriptional-regulator
MNIEELALHCGFNSRASFYRNFNQEMGCSPIEFREKSVMK
>NZ_CP030848.1|WP_149525858.1|2189733_2191296_+|helix-turn-helix-domain-containing-protein
MYRHILSIFFYFSIVFIALGQSSNFDSLYNDCHKQYMESDVEGAAAIGDSVFEAAKTDEQKIKSYILNSNIQQSLGNIQGAIKYATIGDRLAQLTGYNRWRAVFSKILATNFREPGLYEQSRAYLATAERMCDLLDDADVRADIQIELFQEKALYKMNTRSYRVALELLDSAKRLIALDSESNSTLRLKKAANYHLQGICELELGNADLSYELMHTSLSFLSEVDRNIIPFVYRGLAELHLKLSNLDSCKHYLDYTSAYIIKPGRLRLKELYTATSAKYYMLSGNDKMANEFLQKQQVLDADRYLIGQEISSRIIMELRKEDLENRKYKLLFWWCISVTSVIVILLLVYQIRFSRFNRVIVTTNLNYREEPKKQELSNHLAQENRSSTESSGTDSELNIALETETRLIRELSALEHENFFLERDLTLNKLASRLSSNQKYVSHIIKKYRNLDFNDYLQHKKINYLLEKINTDHTLLDYKLAYLAELSGFSSHSKFTTAFKSVMGKTPSQYIEEIRSEVSI
>NZ_CP030848.1|WP_149525859.1|2191825_2192986_+|hypothetical-protein
MDITYYIQYYALYLESKFFGYPLIIRLTVLLVSILVLVYIFSLIRFLAINLYHKAIERRKNRIETKMGDRINAIIFEERNLSEEHVAFQLADSIRLVKNKQDKMVFTDIIIDLIQIGSGKKNKVNQQNVRALLNAYAIPCFWEKELLSSSSSRRRNALRKLDDLGNGCAGAIIMRSAYHKDKGLRKHARAAALQYDTNDPFKFLEDSFDSDFNALDEILIHHFLTSRAKSGPLPLLTRWVRTSENEAFKAFMIKEIGFFKQTEATPILASMLETESSSILKISIIETLGKLGHQEVEPNLFKLFPMTSKDVPRAIIKAITHFKTAEGLGFLCYSYNRIFDNELKIEVAYAIQQYGEEGSTALRELSAKSNEFGKKIFDQVNYQSGL
>NZ_CP030848.1|WP_149525860.1|2193004_2194441_+|glycosyltransferase
MLDILFSIYGYGIFFYATSITLIYLSLAVMGYFNIWRHKTRYTVREERILVEYPEAAPGISIVAPAYNEEVIVIDSVKSLLSLNYPNYEIIIVNDGSTDNTLDLLISNFEMVEVPYAYINKVECRPMKRVFKSFNPLYDKVIVVDKVNGGTKADAMNAGVNVAKYDYFINTDVDCILAPDTLTKVILPVLDSDIPVIAVGATMRMANGCEVQEGKITRVRPPRQVIPTFQETEYLRSYLVAKMGWSAINSIPNVSGGFGLFEKQTVIDCGGFDTNSHAEDMDMTLRMIAYKREHKEPYRIVQTPFTCCWTEGPPNLNVLARQRTRWGRGLLQIFFVHRRFLFNKRYGRMGLVIMPYALFFELLAPIIETTGVFFLIFQLYTEQINFNTFWLMLLYVYLIGVSISTLTIVFDLSIKKQYKTFAEYLKLILFSSFEAFFYHPFVVFFSLRGYWQFLTKKKFKWGTMTRQGFQSNTESKAA

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Crispr_ID: NZ_CP030848_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_8

2202381-2202474

Orphan

Consensus_repeat	Method
TTTGCTAGTTCTTATATCTAAACTCTAATGTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_8

>merge|NZ_CP030848|8|2202381-2202474|CRISPRCasFinder
TTTGCTAGTTCTTATATCTAAACTCTAATGTCTTAAATCTAATAAAAAACTATTCTAGCATTTTGCTAGTTCTTATATCTAAAATCTAATGTCT

>NZ_CP030848|8|8|2202381-2202474|CRISPRCasFinder
TTTGCTAGTTCTTATATCTAAACTCTAATGTCT	TAAATCTAATAAAAAACTATTCTAGCAT
TTTGCTAGTTCTTATATCTAAAATCTAATGTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525872.1\|2207874_2208435_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
NZ_CP030848.1\|WP_149525870.1\|2206101_2207232_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|366736
NZ_CP030848.1\|WP_149524797.1\|2203527_2204436_-\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525875.1\|2211507_2212143_-\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP030848.1\|WP_149525871.1\|2207233_2207872_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374294
NZ_CP030848.1\|WP_149525867.1\|2201451_2202297_+\|glycoside-hydrolase-family-25-protein	unknown	unknown	gnl\|CDD\|119384
NZ_CP030848.1\|WP_149525869.1\|2204569_2205889_-\|DUF21-domain-containing-protein	unknown	unknown	gnl\|CDD\|224173
NZ_CP030848.1\|WP_149525868.1\|2202487_2202784_+\|thioredoxin	unknown	unknown	gnl\|CDD\|239245
NZ_CP030848.1\|WP_149525858.1\|2189733_2191296_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NZ_CP030848.1\|WP_149525863.1\|2197262_2199386_+\|DUF4838-domain-containing-protein	unknown	unknown	gnl\|CDD\|374379
NZ_CP030848.1\|WP_149525859.1\|2191825_2192986_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP030848.1\|WP_149525874.1\|2210961_2211609_+\|ligase-associated-DNA-damage-response-endonuclease-PdeM	unknown	unknown	gnl\|CDD\|274996
NZ_CP030848.1\|WP_149525864.1\|2199399_2199909_+\|DUF1573-domain-containing-protein	unknown	unknown	gnl\|CDD\|377880
NZ_CP030848.1\|WP_149525865.1\|2200025_2200430_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP030848.1\|WP_149525873.1\|2208527_2210969_+\|ligase-associated-DNA-damage-response-DEXH-box-helicase	unknown	unknown	gnl\|CDD\|274994
NZ_CP030848.1\|WP_149525861.1\|2194472_2195921_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP030848.1\|WP_149525862.1\|2195890_2197276_+\|YaiO-family-outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|275183
NZ_CP030848.1\|WP_149525860.1\|2193004_2194441_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133045
NZ_CP030848.1\|WP_149525876.1\|2212145_2212487_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525866.1\|2200516_2201401_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226304

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525872.1\|2207874_2208435_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	6.81266e-44
NZ_CP030848.1\|WP_149525870.1\|2206101_2207232_+\|phosphotransferase	gnl\|CDD\|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	3.3007e-18
NZ_CP030848.1\|WP_149525875.1\|2211507_2212143_-\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	3.61177e-07
NZ_CP030848.1\|WP_149525871.1\|2207233_2207872_+\|hypothetical-protein	gnl\|CDD\|374294	pfam16011, CBM9_2, Carbohydrate-binding family 9. CBM9_2 is a family of putative endoxylanase-like proteins that belong to the Carbohydrate-binding family 9.	1.82515e-63
NZ_CP030848.1\|WP_149525867.1\|2201451_2202297_+\|glycoside-hydrolase-family-25-protein	gnl\|CDD\|119384	cd06524, GH25_YegX-like, YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins.	3.93572e-73
NZ_CP030848.1\|WP_149525869.1\|2204569_2205889_-\|DUF21-domain-containing-protein	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.82142e-119
NZ_CP030848.1\|WP_149525868.1\|2202487_2202784_+\|thioredoxin	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	3.07405e-37
NZ_CP030848.1\|WP_149525858.1\|2189733_2191296_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	6.8165e-10
NZ_CP030848.1\|WP_149525863.1\|2197262_2199386_+\|DUF4838-domain-containing-protein	gnl\|CDD\|374379	pfam16126, DUF4838, Domain of unknown function (DUF4838). This family consists of several uncharacterized proteins found in various Bacteroides and Chloroflexus species. The function of this family is unknown.	2.1141e-54
NZ_CP030848.1\|WP_149525859.1\|2191825_2192986_+\|hypothetical-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	7.73654e-06
NZ_CP030848.1\|WP_149525874.1\|2210961_2211609_+\|ligase-associated-DNA-damage-response-endonuclease-PdeM	gnl\|CDD\|274996	TIGR04123, hypothetical_protein, metallophosphoesterase, DNA ligase-associated. Members of this protein family are an uncharacterized putative metallophosphoesterase associated with a DNA ligase, a helicase, and a putative exonuclease. It may play a role in DNA repair. Its system is present in about 12 % of prokaryotic reference genomes.	9.93124e-62
NZ_CP030848.1\|WP_149525864.1\|2199399_2199909_+\|DUF1573-domain-containing-protein	gnl\|CDD\|377880	pfam07610, DUF1573, Protein of unknown function (DUF1573). These hypothetical proteins, from bacteria such as Rhodopirellula baltica, Bacteroides thetaiotaomicron, and Porphyromonas gingivalis, share a region of conserved sequence towards their N-termini.	1.68069e-17
NZ_CP030848.1\|WP_149525865.1\|2200025_2200430_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.83611e-06
NZ_CP030848.1\|WP_149525873.1\|2208527_2210969_+\|ligase-associated-DNA-damage-response-DEXH-box-helicase	gnl\|CDD\|274994	TIGR04121, ATP-dependent_helicase, DEXH box helicase, DNA ligase-associated. Members of this protein family are DEAD/DEAH box helicases found associated with a bacterial ATP-dependent DNA ligase, part of a four-gene system that occurs in about 12 % of prokaryotic reference genomes. The actual motif in this family is DE[VILW]H.	0
NZ_CP030848.1\|WP_149525861.1\|2194472_2195921_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	6.47222e-12
NZ_CP030848.1\|WP_149525862.1\|2195890_2197276_+\|YaiO-family-outer-membrane-beta-barrel-protein	gnl\|CDD\|275183	TIGR04390, hypothetical_protein, outer membrane protein, YaiO family. Members of this family share a domain of bacterial outer membrane beta barrel, up to the protein C-terminal residue (usually Phe or Trp). The member YaiO was shown experimentally to be localized to the outer membrane. [Unknown function, General].	1.35563e-06
NZ_CP030848.1\|WP_149525860.1\|2193004_2194441_+\|glycosyltransferase	gnl\|CDD\|133045	cd06423, CESA_like, CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.	2.56114e-51
NZ_CP030848.1\|WP_149525866.1\|2200516_2201401_-\|hypothetical-protein	gnl\|CDD\|226304	COG3781, COG3781, Predicted membrane protein [Function unknown].	2.05293e-55

>NZ_CP030848.1|WP_149525867.1|2201451_2202297_+|glycoside-hydrolase-family-25-protein
MSKSRKSGKKKVQTDKQVQRKLLIWSIAIPLALVFLIFAIQHRAGISYLFVKWFEKGKIEREDLSKYDIRNKELMRRYDDKIYGIDVSQYQGDISWDEVLTIHDEFPVDFIFVRATMGERAKDRAFKENWKAIKKRNKLRGAYHYFRPNENSTKQANNFIKTVKLESGDLPPVLDIEEMPRNQSMDSLKVGLKRWLTLVENHYDIKPILYSGDKYFADFLEKEFEDYTLWIANYNFWVERPEKHWNFWQFSEKGSVRGIKGPVDLNMFTGTIEDLEELCRD
>NZ_CP030848.1|WP_149525866.1|2200516_2201401_-|hypothetical-protein
MIVYNPKDWFKTISYLHNSKIFKRLLPYLIISIFVSWGLAYLELEYLKLSDRSWIKNITTVHNLLGFVLSLLLVFRTNTAYDRWWEARKQWGALTNTSRTLAIKMNAFLDPQDKVNRSFYRKSIALFAETLYTYLRSDYTKFMLDEVEHPELNALDEKKHGPNQVAALIYKKTNILYKDGKLSGDQFILINKELTALTEVTGACERIKNTPIPLGYSAFIKTFIVLYTATLPIGLVFSMGYFVTAAVPFIFYVLATLEMIGESIEDPFGSDSDDLPIEKISANIKKHTQEVLLP
>NZ_CP030848.1|WP_149525865.1|2200025_2200430_+|helix-turn-helix-domain-containing-protein
MIAKNESSNTKAYMSHETEGKLLNALNEWEQERYFLNPACSITSAAREIGCNSKYLSYVVNKNKGSDFPNYVNILRICFLEDYLRKTEQARSFKLAYLAAYCGFSSYGKFAKSIKDHRGLNPTQFIVYFDQNIA
>NZ_CP030848.1|WP_149525864.1|2199399_2199909_+|DUF1573-domain-containing-protein
MSKLVYSCYILLIIFSSCTDFKGKKTKIEIIDNDRHYYPILTGQELDVVYKFKNTGDVPLLLTDIITSCGCLVVNKITTKNVPPGEEGIISLRFNSAKNVGYAKHYIELYGNFATTDKEELIFDVNVVPNALYTKDYEELHQEAKDKNGAIEDMVDGKENNLGYYLDLN
>NZ_CP030848.1|WP_149525863.1|2197262_2199386_+|DUF4838-domain-containing-protein
MLLFNIIFSCFIMLFTSCESDFYGLDANAYVLTAEQDAASEQWQEYLFNHLSKRTSKKDLFSRAEDNENIPANHKQIHVEIAADLNNDYCIQHTKDKLHIRVKTKAIATWMSYQLIESLGQVKKEIKTEDLPPAYLTFTNQCKDFDFTYREPHYAPNTNVEYAALLGTNNLDTEWGIWGHNITRIIQDAPGVWAEVNGKITQEQYCFSGDTLYNQLKEYIQDNFSDKPEEGMKFMIAPNDNLLSCTCDRCQAAGNTDKNAAPAVVLLINKLAKQFRQHQFFTIRYHSVNEPPAYAFEDNAGLFFSTIELPKITNFKDNSKFQSFIDEIEAWKSKTKTIYLWDYSSNFDDYLTPLPSLNVLKAQLQGFKEEGVEGIFLNAAGYDYSSFDDLKTYVAAALMINTELEIDKLTKAYLKKFYPKSHQLLADCYLQLEDDFATKAKPYSLYAGFPEVKSSYFNASNFLSLNESLQKVLPKTKGYEREALEKLLAAFRYTRLQIAYSNGLNKGGAFEVVDHYVRPNRFANTLMKQLKKDVDDGKLKVFKESNGDLGEYLAQWNAYAGKLQKPNQLKSTKLLSVVSNENDVLDKTLLADGILGFNNDFHQGWVTASKTMTLILEEGAFEQMKEMKLRFLKNTRHQYGAPTKVEVLQGGKVIFRTDIVDTNEGDSVYTLTIPVEKFEANTICEIKISTSNPQLSRLGLDEVQVFN
>NZ_CP030848.1|WP_149525862.1|2195890_2197276_+|YaiO-family-outer-membrane-beta-barrel-protein
MRLQQYDKAVSSYEGLLASLKPDQQFYYLSGFNDMMAQVVKESTEAQRYRDAMNWVNRWLDVSPKNQQALLYAVNLSHQMQDKGQMLTFAKRANEAFPDESIFKVRLASAMQLNGAPTKDIWALMGEEVIRNPYHNEVVNAYVQASHDHAAQLLSEKAENEALLVADKGLQYKPANKELKYLKGLAYEKLKQYDSAFYYQSFYEPSLLELDEFKANLKYLNYKMYQNEFAISHMRSRYGDYYSIQTISALEYMRMCAKNNYTARVFYSGREEGKGVQGQLEWGRNWSSHWASRVDFSVSNKYFSKFAVHGAIIRTFPKDWELELGVGHRKLYNDEKLSSAVVGVGKDFNQFRLQAKFTQAGLQEKWVYNVAAQARYSFDNPKNYVLALANMGSTPDVDILDYQRLNTLSVMNSMVGAGVGRLLTKNVSASVMGTWYNFQTSPNPEQYRNLYNLFLQVNVAF
>NZ_CP030848.1|WP_149525861.1|2194472_2195921_+|tetratricopeptide-repeat-protein
MNRKYTYLRTGMFMLLLCTGSMVDFSGNRLYGQQKVSISDKGDVVKKINSLYQAGKLQDGKQLTEINLKKSPKDSDLKMLLGKYYVLTKQYDKARFELNKSLEFNPGNVDSRHLLVTVETETKRYSSAICYVNELLEVNPYWKGLWRKKIELYRLQGNEVEANRLLKRISQIFPEDGQIQDDLNYQMELTANSKRKSGRIDDAIEVNKLLLQEKPKNIEVYMDLINGYIKAGDYNSALVTTERGLNAFPTNSALRQKKVALLEQNKRYDEILAFIKNDPSAINGGQYQYFLLEAGRSAKQNDPAVLYGKILDATPGNDEAFQVVFNSLVAQQQYDEALHRLHSFMRIKGNSKTLSAKELELYRLKNDQSKVNQLTKTMFLNYPNDSDLKDGYVRVISSEIKDHLAAEEWNLAETKLRQLIPHANAEYRDFINNGLLNAYYQQGKFSDALQILEEMHRANPSDANLAIKSRAYICAFSSMIRL
>NZ_CP030848.1|WP_149525860.1|2193004_2194441_+|glycosyltransferase
MLDILFSIYGYGIFFYATSITLIYLSLAVMGYFNIWRHKTRYTVREERILVEYPEAAPGISIVAPAYNEEVIVIDSVKSLLSLNYPNYEIIIVNDGSTDNTLDLLISNFEMVEVPYAYINKVECRPMKRVFKSFNPLYDKVIVVDKVNGGTKADAMNAGVNVAKYDYFINTDVDCILAPDTLTKVILPVLDSDIPVIAVGATMRMANGCEVQEGKITRVRPPRQVIPTFQETEYLRSYLVAKMGWSAINSIPNVSGGFGLFEKQTVIDCGGFDTNSHAEDMDMTLRMIAYKREHKEPYRIVQTPFTCCWTEGPPNLNVLARQRTRWGRGLLQIFFVHRRFLFNKRYGRMGLVIMPYALFFELLAPIIETTGVFFLIFQLYTEQINFNTFWLMLLYVYLIGVSISTLTIVFDLSIKKQYKTFAEYLKLILFSSFEAFFYHPFVVFFSLRGYWQFLTKKKFKWGTMTRQGFQSNTESKAA
>NZ_CP030848.1|WP_149525859.1|2191825_2192986_+|hypothetical-protein
MDITYYIQYYALYLESKFFGYPLIIRLTVLLVSILVLVYIFSLIRFLAINLYHKAIERRKNRIETKMGDRINAIIFEERNLSEEHVAFQLADSIRLVKNKQDKMVFTDIIIDLIQIGSGKKNKVNQQNVRALLNAYAIPCFWEKELLSSSSSRRRNALRKLDDLGNGCAGAIIMRSAYHKDKGLRKHARAAALQYDTNDPFKFLEDSFDSDFNALDEILIHHFLTSRAKSGPLPLLTRWVRTSENEAFKAFMIKEIGFFKQTEATPILASMLETESSSILKISIIETLGKLGHQEVEPNLFKLFPMTSKDVPRAIIKAITHFKTAEGLGFLCYSYNRIFDNELKIEVAYAIQQYGEEGSTALRELSAKSNEFGKKIFDQVNYQSGL
>NZ_CP030848.1|WP_149525858.1|2189733_2191296_+|helix-turn-helix-domain-containing-protein
MYRHILSIFFYFSIVFIALGQSSNFDSLYNDCHKQYMESDVEGAAAIGDSVFEAAKTDEQKIKSYILNSNIQQSLGNIQGAIKYATIGDRLAQLTGYNRWRAVFSKILATNFREPGLYEQSRAYLATAERMCDLLDDADVRADIQIELFQEKALYKMNTRSYRVALELLDSAKRLIALDSESNSTLRLKKAANYHLQGICELELGNADLSYELMHTSLSFLSEVDRNIIPFVYRGLAELHLKLSNLDSCKHYLDYTSAYIIKPGRLRLKELYTATSAKYYMLSGNDKMANEFLQKQQVLDADRYLIGQEISSRIIMELRKEDLENRKYKLLFWWCISVTSVIVILLLVYQIRFSRFNRVIVTTNLNYREEPKKQELSNHLAQENRSSTESSGTDSELNIALETETRLIRELSALEHENFFLERDLTLNKLASRLSSNQKYVSHIIKKYRNLDFNDYLQHKKINYLLEKINTDHTLLDYKLAYLAELSGFSSHSKFTTAFKSVMGKTPSQYIEEIRSEVSI
>NZ_CP030848.1|WP_149525868.1|2202487_2202784_+|thioredoxin
MASFNELIQGNKVVLVDFSAAWCGPCQTLAPILKEVKEEIGDSLSIIKIDVDRNQALAAKFQIQGVPTLILYKNGEQVWRQSGLLQRSELVKLIRNLR
>NZ_CP030848.1|WP_149524797.1|2203527_2204436_-|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVIEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSRVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149525869.1|2204569_2205889_-|DUF21-domain-containing-protein
MVTEIVIILILIILNGILSASEIAIVSSRKARLQAASEKNAGAKKALELKDNPNNFLSTVQIGITLIGILTGFFSGGSISTFLAEQMNQVSFLAPYSSQIAVIVVVLTITYLSLVIGELVPKRIGMAIPEKYASFIALPMNLLSKIVKPFVWLLSVSTDFIVKLFNIKSNQNAVTEEEIKALVDEGVDSGAIEGIEHDMVDRVLSLGDKRAINLMVHRSKITYLDIQKSFEENKAYILADEHTEYPVCNGNFDHVIGVVHIKTLFKEYLTSDEPELTNLLQPIPFINENTYAYNVMQSMKTSGVMQAVVVDEYGSPQGIITMADLVGSLVGGFDSPEDDEKKTIRQREDGSYVIDGSYQLDDFIELFKIDLTEDDEDEIGNLTTVAGLVFLLLDHIPEEGEQVVYKNLEFEVLDMDGHRIDKLIVNVQGETSDETANID
>NZ_CP030848.1|WP_149525870.1|2206101_2207232_+|phosphotransferase
MKSEVMSTNTIENSILSAEKFKIQGNIVSSVPFGSGHINDTFKIVTDSDINEQYLLQRINHHVFRNVDGLMDNIEKVCLHLKQKLAHLGQEEVAKRTMTLIPTWDGQHYYKDENGDFWRVFILIPDTRSYDILETTDQAFSGGMAFGQFQKQLSDLDPTTIVEVLPNFHNIEFRMNNLREAIANDRAGRVAEVQDLLDYIFEREDKMRTILELGRANKLPLRITHNDTKFNNVLLDSNDQVQCVIDLDTVMPGYVAYDFGDAIRTIINSAAEDEADVSKIVLNVPLFEAFTAGYLSEAKEFLSEIEVESLIHGVHLLPYMQAVRFLTDYIDGDTYYKIGYPEHNLVRTKAQLKLVQELEANHKVLTDILAANLNSN
>NZ_CP030848.1|WP_149525871.1|2207233_2207872_+|hypothetical-protein
MKTLEIEKVDFQESAGDYASLAKNMNSLAWHDIAAAPWKSEFPYIPKVQFQVGYSDQDILLHYSVEEEFVKGQYIRPNENVWEDSCVEFFVSFDNRETYYNVEFNVLGVGLVGYGTSIKSNRNRLSAEEILQINAYSSVRTVAGKKSWQQILQIPFHIFKANAEELQGKKAYANFYKCGDALPNPHFIAWNDIDNPTPNFHLPQYFGEVTFK
>NZ_CP030848.1|WP_149525872.1|2207874_2208435_-|NAD(P)H-dependent-oxidoreductase
MEKIQVGLFVGSLRKESFNKKIANHLISIAPEGYEYKIIEIGQLPFYNEDLEGDKLPDSYKSFRAEVEALDAVIFVTPEYNRSVPAVLKNAIDVASRPYGKGKWGKKPGAVISSSIGAIGGFGANHHLRQSLVFVDIPAMAQPEAYIGNAAKLFDEQGKLTNEDTAKFLKDYVAAFSEWVEKSVKK
>NZ_CP030848.1|WP_149525873.1|2208527_2210969_+|ligase-associated-DNA-damage-response-DEXH-box-helicase
MKNELADVWFYNQGWEPHDFQKQCWKEIAANRSGILNAPTGYGKTFAIWFGVIQHYYSDAYQAKLEKQRKRGLHALWITPLRALSKEIHRVTEGVSLDLDLDYQIELRTGDTSTAIRQKQRKNPPKALITTPESVHLILATKQGQDFFKQLEFIVVDEWHELLGSKRGVLIELALSRLKSINPNLKIWGISATIGNLEQAKDILLGASNSGVMVKAQINKKIDIQTILPDSLEKFPWAGHLGIRLLDKVVDVVNQYGTTLIFTNTRSQAEIWYQQIISNYPEFAGLLAIHHGSLSDEVRMWVEEALHAGRLKAVVCTSSLDLGVDFRPVDCVIQIGSPKGVARFLQRAGRSGHRPDATSIIYYVPTNSLEIIEGDSLKFAVKEKIVEQRIPYIRSFDVLTQYLMTLAVGDGFDPQQIYQEITNTHCFESVSQEEFDQCMSLLLHGGSSLKAYDDFHRLELVDGLYKVTSRKLAMRHRLSIGAIVSDLMMRVKFLSGKHLGSIEESFISKLNVGDVFWFSGRQLELIQVIANDAIVKPSQKKKGVVPSWMGGRFAISPDLGIAIRHSFSSIHKKSGQSPEIKFLQPLFKEQERVSGLPKEDELLVEYTETRYGFHLFLYPFDGKLVHEGMAQVIAYRLGQISPATFSIATNEYGIELLSDTAYELNEDILKQIFSPHKLHADINSGINVQEMARRRFRDIAGIAGLVFQGFPGKQMKSKHLQANAGLFFSVFSEYEPNNLLLRESYDEVFDFQLEEGRMIKAFERIDSHRIIFRKPEKLTPFAFPIFSESFRERYSNEDWQSKLEKIKMQLIDG
>NZ_CP030848.1|WP_149525874.1|2210961_2211609_+|ligase-associated-DNA-damage-response-endonuclease-PdeM
MAKKLVLNGLDCFLLPQKAMYIAKYQLLVVSDWHLGKLKHFRKEGFFVPAPNVTEELGRLDILLNELEVKQVVFLGDLFHSKLNSDWEQFCIYTKAKPHITFTLTKGNHDILEDAHLERSALRIVDHLLLEEGLVLSHEPLLGLDSHIINVVGHIHPGCQVFLAGRQSFRLPCFHLENRVLTLPAFGKFTGLHILPKTSLTKVYAIVDQSVLELP
>NZ_CP030848.1|WP_149525875.1|2211507_2212143_-|DinB-family-protein
MENQQNLEVWMRGPIEGISVILQPAAHALLQVKEDIPKLLNSEDDQYIWIKPFGMASSAFHVLHIIGVIDRMFTYAAGKSLSEEQFEYLDKENSPNQDISVDEMLDNLNHAVERATNDLKEIDDITLTEERFIGRKMIPTTQLGLLFHAAEHAQRHYGQLLVTIKTVRGLFQQGSIHYLRKLQHRLVYDGIYLSQACLRKNMQTGKLSECR
>NZ_CP030848.1|WP_149525876.1|2212145_2212487_-|hypothetical-protein
MVKMLYFVAFWLTQIVSSIIFKYGGINPKFQWPALIIGNIIILSASWFLVQLFKNFSQPIVIAVCSGGTFLTVQLAMALWFKESLNWIQVLGCLVIVFGMAMITFGGKQSVTP

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Crispr_ID: NZ_CP030848_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_9

2229140-2229236

Orphan

Consensus_repeat	Method
ATCCTTCCTTTCCTGGTTCAAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_9

>merge|NZ_CP030848|9|2229140-2229236|CRISPRCasFinder
ATCCTTCCTTTCCTGGTTCAAGAAAAAATCGTCATCCATTTTTTTTCTTTCCACTCGATCCTGATAATCCCTAAATCCTTCCTTTCCTGGTTCAAGA

>NZ_CP030848|9|9|2229140-2229236|CRISPRCasFinder
ATCCTTCCTTTCCTGGTTCAAGA	AAAAATCGTCATCCATTTTTTTTCTTTCCACTCGATCCTGATAATCCCTAA
ATCCTTCCTTTCCTGGTTCAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149525880.1\|2220537_2221272_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_CP030848.1\|WP_149525881.1\|2221264_2222107_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|377053
NZ_CP030848.1\|WP_149525897.1\|2239654_2239900_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525890.1\|2232981_2233167_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525896.1\|2238673_2239084_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525878.1\|2216488_2219344_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|369392
NZ_CP030848.1\|WP_149525882.1\|2222229_2222523_+\|DUF2892-domain-containing-protein	unknown	unknown	gnl\|CDD\|378561
NZ_CP030848.1\|WP_149525886.1\|2225388_2226333_+\|homoserine-O-succinyltransferase	unknown	unknown	gnl\|CDD\|235433
NZ_CP030848.1\|WP_149525879.1\|2219539_2220346_-\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	unknown	unknown	gnl\|CDD\|237766
NZ_CP030848.1\|WP_149525889.1\|2230303_2232985_-\|Plug-domain-containing-protein	unknown	unknown	gnl\|CDD\|369481
NZ_CP030848.1\|WP_149525893.1\|2235393_2236767_+\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP030848.1\|WP_149525884.1\|2223554_2223797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525888.1\|2229389_2230208_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP030848.1\|WP_149525887.1\|2227214_2228774_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379166
NZ_CP030848.1\|WP_149525891.1\|2233439_2234378_+\|ring-cleaving-dioxygenase	unknown	unknown	gnl\|CDD\|319935
NZ_CP030848.1\|WP_149525894.1\|2237047_2237578_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525883.1\|2222678_2223362_+\|NAD-dependent-deacylase	unknown	unknown	gnl\|CDD\|238703
NZ_CP030848.1\|WP_149525895.1\|2237994_2238225_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525892.1\|2234396_2235014_+\|phospholipase	unknown	unknown	gnl\|CDD\|223477
NZ_CP030848.1\|WP_149525885.1\|2223877_2225212_-\|NADP-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|181834

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149525880.1\|2220537_2221272_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	8.22849e-51
NZ_CP030848.1\|WP_149525878.1\|2216488_2219344_-\|transcriptional-regulator	gnl\|CDD\|369392	pfam07495, Y_Y_Y, Y_Y_Y domain. This domain is mostly found at the end of the beta propellers (pfam07494) in a family of two component regulators. However they are also found tandemly repeated in CTC_02402 without other signal conduction domains being present. It's named after the conserved tyrosines found in the alignment. The exact function is not known.	1.66943e-09
NZ_CP030848.1\|WP_149525892.1\|2234396_2235014_+\|phospholipase	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	3.48949e-20
NZ_CP030848.1\|WP_149525882.1\|2222229_2222523_+\|DUF2892-domain-containing-protein	gnl\|CDD\|378561	pfam11127, DUF2892, Protein of unknown function (DUF2892). This family is conserved in bacteria. The function is not known.	1.18229e-06
NZ_CP030848.1\|WP_149525886.1\|2225388_2226333_+\|homoserine-O-succinyltransferase	gnl\|CDD\|235433	PRK05368, PRK05368, homoserine O-succinyltransferase; Provisional.	0
NZ_CP030848.1\|WP_149525879.1\|2219539_2220346_-\|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase	gnl\|CDD\|237766	PRK14609, PRK14609, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional.	1.28234e-137
NZ_CP030848.1\|WP_149525889.1\|2230303_2232985_-\|Plug-domain-containing-protein	gnl\|CDD\|369481	pfam07715, Plug, TonB-dependent Receptor Plug Domain. The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.	0.0046242
NZ_CP030848.1\|WP_149525893.1\|2235393_2236767_+\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP030848.1\|WP_149525881.1\|2221264_2222107_-\|restriction-endonuclease	gnl\|CDD\|377053	pfam03477, ATP-cone, ATP cone domain.	1.94454e-08
NZ_CP030848.1\|WP_149525888.1\|2229389_2230208_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.12901e-22
NZ_CP030848.1\|WP_149525887.1\|2227214_2228774_+\|hypothetical-protein	gnl\|CDD\|379166	pfam13402, Peptidase_M60, Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.	3.72636e-55
NZ_CP030848.1\|WP_149525891.1\|2233439_2234378_+\|ring-cleaving-dioxygenase	gnl\|CDD\|319935	cd08347, PcpA_C_like, C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The C-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	1.92296e-63
NZ_CP030848.1\|WP_149525883.1\|2222678_2223362_+\|NAD-dependent-deacylase	gnl\|CDD\|238703	cd01412, SIRT5_Af1_CobB, SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. CobB is a bacterial sirtuin that deacetylates acetyl-CoA synthetase at an active site lysine to stimulate its enzymatic activity. .	1.63748e-98
NZ_CP030848.1\|WP_149525885.1\|2223877_2225212_-\|NADP-specific-glutamate-dehydrogenase	gnl\|CDD\|181834	PRK09414, PRK09414, NADP-specific glutamate dehydrogenase.	0

>NZ_CP030848.1|WP_149525887.1|2227214_2228774_+|hypothetical-protein
MKRTILTLAVACLMASMGYAQSAKEVKHTYQQLSVFEDPLALTLKKGTSKKIINKIEDEHIRKHALNVLAGNYKSDYKLADYHAILSPTTLGHQLSIGDGYSKYQNITGVYLPVGKHIVLAEGIERGKDIKLIVPNWLRQAPDPKEPTKDPKGWGIEKEVFELQNGVNIIDLKDFGSLAYIYYFSENPKEEKPIRVHFLTGQVNGYFDSQKQNNADWDKLLDKAVYGVVDAKGKYIQTAYPVADLKKYAGGKGVELINNYDSLVHRQHRIMGLIKYNRVPENKILSRVNYNYYMFRDGDGVAYMGGKSGYAMAMVLDPARVISGDPCWGFSHEVGHVHQTRPKLSWGGLGEVSNNIYSLYVTTSFGNKSRISEQGNYAKARASIIDKKISYLQDPDVFNRLVPFWQLQLYYAGPGKKADFYPNLFETFRQQESKENPWNRDRNPAVHQLNFVKTACEVAKEDLTDFFDQYGFFYVGEFEMDDYGKYDYRMTQAMVDKCKAEIKALNLPKPKGDISAMKD
>NZ_CP030848.1|WP_149525886.1|2225388_2226333_+|homoserine-O-succinyltransferase
MPVKIPDNLPAIELLKKENIFVMSDLRADTQDIRPMKLLVLNLMPLKISTETDFIRLLSNNPLQVELDFLRLATHNPKNTPEEHLELFYKNFEDIKENTYDGMIITGAPVEMMPFEQVTYWPEVTKIFDWARKHVFSTLYICWASQAALYHFYGVEKKPLDSKLFGVFKHTAWDKKDPLFRGFDDEFYIPHSRHTTILAEDVEAKKDITVLSASKEAGLAILSTRGGRELYLTGHSEYAPLTLHEEYTRDIEKGLEIDVPVNYYQDDKPELGPVVRWAGHANLLFNNWLNYYVYQETPYDLKQVPELGDIKING
>NZ_CP030848.1|WP_149525885.1|2223877_2225212_-|NADP-specific-glutamate-dehydrogenase
MSLNLKNFIKNVELRNPNEPEFLQAVTEVIEDLIPYINEHRPDFADLRILERMVEPERALSFRVAWMDDKNQIQINRGYRVQMNSAIGPYKGGLRFAPDVNLSILKFLAFEQVFKNSLTSLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMTELYRHIGAETDVPAGDIGVGSREIGYLFGQYKRIQNNFTGVLTGKGPQWGGSYIRPEATGYGLLYFVQCVLDYNNESIEGKVISISGAGNVAYYAAEKGIQLGAKVITLSNSTGTLYDKEGLTLEKLAYIATLGRDLAKFTKKYPSATFHAKENPWQFKCDIALPCATQNEINEADAKKLVKNGCTIVAEGANMPSTAGAIKVYDSAKIHFGPGKAANAGGVAVSGLEMSQNAIGQQWNHEKVDHRLKLIMENIHKTCVRYGKEPNGYVNYLKGANIGGFIKVAEAMKAQGVV
>NZ_CP030848.1|WP_149525884.1|2223554_2223797_-|hypothetical-protein
MRVLAELPHPDCKITIFGMNQKFIVKFEQGTLEQSYKLAEADVVGGVNGVFEMLDEEFIQQVIGLFAEMRKAIIGTYNKY
>NZ_CP030848.1|WP_149525883.1|2222678_2223362_+|NAD-dependent-deacylase
MKKIVVFTGAGISVESGLPTFRGADGLWEGYRIEEVATPEAWQRNPELVQRFYNMRRKDCIRVEPNAAHRYLANMEKDFDVQIITQNIDDLHERAGSSKVLHLHGQIRKSQSSKNPNLVYDIEGDEIAMDATCELGSTLRPHVVWFGEAVPNMVEASRLVRDADVFIIIGTSLQVYPAANLLFDCKPGCQIILIDPNAKQVAIPANVHKIAESASKGVVYLAEIIGK
>NZ_CP030848.1|WP_149525882.1|2222229_2222523_+|DUF2892-domain-containing-protein
MSGILNYAFDALKNKLDASCHDGNVGTSERILSVVAGGFLLGRGIKSIVKHPMTAFSGITLGGALIYRGVTGYCPIKDSVESKEPEATVIEHRYFVK
>NZ_CP030848.1|WP_149525881.1|2221264_2222107_-|restriction-endonuclease
MLVKKYSGELVPFDESSLRRSLMRSGASDGEVQMVYASIKNKLYDGISTRELYEMAFDALKSKKNSYAARYSLKRALRELGPEGFYFEKWVARLFQEDGYEAITGQTVQGHAVTHEIDVVAAKGDVMLAVECKFRNDEDAKISVTTPMYFKSRVTDVTGIEYPFFNAHRQFTDGWLVTNAYLTTDSIKFGEYYKMNLLSWDYPNGQSIKARVDNTGEYPITCLTNLTTQDKAMLLKNQCICVKDLLKDPKILSHIQIPADKQKHIMQEAEELINSPIEHE
>NZ_CP030848.1|WP_149525880.1|2220537_2221272_-|TIGR00730-family-Rossman-fold-protein
MSNKFVREEISFLKGARGRWNELKYVIGVFFQFMKGFRTLHFVGPCVTVFGSARFGEDHVYYKQARSVSGKLAEQGFTIMTGGGPGIMEAANRGAKDVGGASVGCNIVLPHEQMHNPYMDKFVNIEYFFVRKELLRKYSFAFIIMPGGFGTLDEFFETLTLIQTKKLSQFPIVVMGLEYHKGIIDHVNEMIEAKTISPEDQDLLLFTDDIDEAVEHIKQYADTNRIINLQEQKPNWILGEKKAV
>NZ_CP030848.1|WP_149525879.1|2219539_2220346_-|4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol-kinase
MLKFANAKINIGLHITERRSDGYHNLETIFYPVKIYDAVETQLSDKLELEIHGADLKADDDNLCLKAYRLLAADYDLPPLKIHLLKRIPIGAGLGGGSSDASATLQLLNEQFELGISDRELEQYAAQLGADCPFFIQNKSTYAEDIGTKLSEIELDLSDYYIVILKPNIHISTAEAYKNVTPLTPHIDLRRAVQLPIQEWKLHIKNDFEAGLFELYPQIGEIKRRFYELGAVYSSMTGSGSAVFGIFEQETDVSEMTSLGKIFLPMDL
>NZ_CP030848.1|WP_149525878.1|2216488_2219344_-|transcriptional-regulator
MPLRTLIFFIASIFTIAFAFGQNIPRVGSPYVKQYNKSTYQAGNQNWGIAVSNEGFIYVANTEGLLSFDGQEWRLHKAKNQRSLRSVNIDKEGRILVGGSGEFGVWERGKFGKMKYRSLSPLVKDQTGLKNDEIWRINTVGNRIFFHSFSKCYIYENNEIKTLTADGEPFLFSHQVNNRMFFEQLPSGLFELVNNSLAQVRGAAVLRGMNILSMLPFDKDKILIATSNHGLFIMENDGSISPWQNQVQQQLIRYQVNNGVKLYGDQFAFGTIQNGVYILNSKGELVQQINKNNGLQNNTVLSMTVDKQANLWVGLDNGVDRIDINSPLYYYADLTGKIGTVYAAIIFQNKVYLGTNQGLFVSDWNGVNDFQSLDFSIVPNSHGQVWQLVNMNGQLLCGHNNGTFLVEGNAMRKISSVTGAWNFTAISGSNRWLQGNYTGIGLMQGGPAPSFIKQFQQIKVPIRSILQRSDSEFWATNQQNVYSMKLNLGKDDAQSINAVKADLPSNTQLHGVYNLANNIVFATDSGFYQYDNILGSFKPYVELNEQLKSFHTANKIIPIKQNEYWFVKKSHIAKVELLPEGKVKIDSSSWNSLRGKMMNDYEQIFNLDDQTSIIGMDNGFAIYFNELSAKANLPKPYITQVWNTSNGTPPLYDDLSIAYGENNLRFAYASPWYSSSNLKYSYWLEGYTDNWSDWEEVAFKDFTNLPDGNYIFHVRSMAPNGTQSEITSLEITIRPPWYRHWLAIVIYLLILTALFIIGKRYYEQHLKKEQQKLKAKMLADQEARLAKEAELNERKLMALKNDQLEQELEIKNRELANAAMNIVYKNEMLNNLHHELTNLNDSNGNKLSSDQLRKVSKLIDEAHSDDRDWDLFEKSFNEAHENFFKKLKSDYPALVPNDLKLCAYLRLNMSSKEIASLLNISTRGVEIRRYRLRKKLNLPTEKNLTEFLLEL
>NZ_CP030848.1|WP_149525888.1|2229389_2230208_+|methyltransferase-domain-containing-protein
MNSKKLVSAKIEDFYNQASEEDRLSKGLGIFEFERIKALISRYLPKLGVVIDVGGGTGKYAEWLAKEGHDVHMVEPLDKHLKIAQKRSEKAKRPFEVIKGEAQRLDFKDGFADVVIMHGPLYHLQSEEARLRAISEAKRVLKPGGVVLGFAINYTASTIVGLLNGLIHGPSFLDMCKSELTTGIHNAPSDLPWVMAESFYHKPAQLKAEFEAAGLRFDKLYAVEGITWLDKHYFESMLNAKKRKNLDLITEITENDEHLLALSPHMMIAAFV
>NZ_CP030848.1|WP_149525889.1|2230303_2232985_-|Plug-domain-containing-protein
MIASLFKKILIAIMLFLSKQITAQTENIDGYILSDGKPIPSVYIRLTSGSKVLAYSNSDNSGYFIIKIPENINISQLHLETSHLSFQPTKTRLSEDKTTYKFILQPKSTEIQALDIKRSQRLRANGDTLVFKVDSFARNEDRTIEDVLARMPGMHVAESGKISFNGKEITAIYLDGSNLLDEKYEFGSKTIPNKIIENIEVLQRHIHHKVLQDNTLSDDIAINLVLKDEATLKVMGRSTLGLGLPEQYDLELSAMLLNKNIKSLNGIHGNNLGKDLSSMFIGHTDFKRNSRIVDPLPKNLLRQETITSATGHPYINNTAKSRFLASNNYFRIRQNGSLRLIAQQHLGRREPLVFSYNDNFASLDSIRFIEDPNSTPVLRGTVLAAQFEINSPTYFLSNNAYMEIDRRKETSDLLGNSMQLNHPYRHKLLQWSNHFRYSPKLKNGDIVDIQWTIEHKDSEERLQVEQFTADPFTTNKKEDIARQQLELPIFANLIRASYKFNKGVLKHSYLLGLLNERQKFNSELDLSGSEYQFSELGLREQINNLDWHNNEFYFVPMLETKVKQWEFSVALPVIAQHIHYLDPTNDLDKSRDKVYFNPLFNSKFFLNSQDYLQLRFQHHRSIGNMANFFCKPILKTYRSLANNMVDLREKKKNELTLKYNIQRPLKLFFGNITAKYASVRYPDLLATLVTDNLLSKIVVPGAHKSQEYGLILFATQYINALRGPLQLHASWTNLKDDMAVQRQATKLDQSAVVINPSIDMQFHKKFSVNYGLHYSWFKSEIVAFHVPSDRIMSSNLIQSIKLAYTPIKPLFVEYSFNHQHNKQGIFTNNHLFMDLFARISLPKRKVDLEVELKNIANIKNYHHQVLTSDELYSTVYHLRGRMLNAQVSLISKT
>NZ_CP030848.1|WP_149525890.1|2232981_2233167_-|hypothetical-protein
MKQQIFTLLGSIFFLYSGQANAQPNETSPFRESYQMTFVDDTNKIIQPLRKSYHRPFEIAP
>NZ_CP030848.1|WP_149525891.1|2233439_2234378_+|ring-cleaving-dioxygenase
MENKVLGLHHITAIANLAQRNYDFYTKVLGLRMVKKTVNFDDPGTYHFYYGDEKGSAGTILTFFPWEGIGRGRNGVGMATEIAYSVPEGSLDFWTERFGENNVLTGEVVERFGELYYPFLDPDGLNLSLVVPKAGDTRTGWTTKEVTQEVASKGFHNTTLTLRELEPTAKVLTDLLGYQQVAEEGNRYRFATDTVDSANIIDILIDPNAGRAINTAGTNHHIAFRVKNDEDQLELRERIMRAGLQITPQIDRDYFHSLYFREPGGVLFEIATENPGFDVDEPLDSLGSALKLPRQYEGSRTEIEKVLPQLEG
>NZ_CP030848.1|WP_149525892.1|2234396_2235014_+|phospholipase
MHQRNILQAGNTSNAKKALIMLHGRGGSAQDILSLAEHLNVADYLLLAPQATNHTWYPHSFMAEVASNQPYLDSALALVAETVKEAEAQGIRAENIYFLGFSQGACLTLEYVARNAQRYGGAVAFTGGLIGDEIYKENYQGDFAGTPIFIGTSDPDFHVPVSRVQESTKLLEEMGAEVTEKIYAGMPHTIVSDEIEVANRVVFRY
>NZ_CP030848.1|WP_149525893.1|2235393_2236767_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MSFTHSQDTIVALATSPGVNGAIAVIRLSGPEAVAITDSVFKGKDLSKQASHTIHFGTIRDGDQVIDEVLVSLFIAPHSYTKENVVEISTHNSKYIIERILTLLMKKGARAAKAGEFTLRAFLNGGLDLSQAEAVADLIASNSAASHQIAMQQMRGGFSNQLKQLREDLVHFASLIELELDFAEEDVEFANRDQLRILIEKIYQVIGRLIQSFEQGNVLKNGVPVVIAGKPNVGKSTLLNALLNEERAIVSDIAGTTRDTIEDEINIHGVTFRFIDTAGIRQTEDLIEAKGVERTMEKMKQARLIIYLFDPTQDHIAAVQQQIKEVEVLNIPFVTIINKSDLLSEDQRAEYAVLNPIYISAKQQQGIEGLKDELLNQVNLSQINTDDTIVTNIRHLEALQHTREALEKVLFGIDNPITSDFLAMDIRQALHHLGEITGTVTTDDLLENIFSKFCIGK
>NZ_CP030848.1|WP_149525894.1|2237047_2237578_+|hypothetical-protein
MREKRFILSVCFLIILFCKIGSAQSLQVGVFNVNGVVYKVDKIANNTDTVVIPRDLVLQPDNPITVNGIPTEILIEGIIVNRDDGWFKYAKETHSASRISQLKANNDWIRFHYWLKSDGTCYYGSFNLKNASSLTITEIAKMYMHIKSNFKPFLMSPDARHLQLNSIPVDGGIQDF
>NZ_CP030848.1|WP_149525895.1|2237994_2238225_+|hypothetical-protein
MNLLFLNIGIQEVILLSMLIPTIFYLYSFYRLVVSRNINANEKLLWIVAFLVFNLLGAIAYWIWDYSNNRVRSSRY
>NZ_CP030848.1|WP_149525896.1|2238673_2239084_-|hypothetical-protein
MKKLIYSIFIIVVLGSCSKNENHIDSKSQILGEWDLIYAAPILHLKKKSFNFGKSELAITGIRLDTKWGGAITAWDDEAAVKFKYSLSEDNKTLTIIYEGNAILDFDILKLDETTLMIQSRFGEQEPYPLHFMRPK
>NZ_CP030848.1|WP_149525897.1|2239654_2239900_+|hypothetical-protein
MLNHFVSVLRTANSGGKTWVKHQQEKMKKQYLKPTVWMDEIQMEEGIAATSANTRPQDEMNTISEEWHQEEDQNKEFDWNF

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Crispr_ID: NZ_CP030848_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_10

2377284-2377395

Orphan

Consensus_repeat	Method
TTTCCTGGTTCAGAATAGTAGTTAGTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_10

>merge|NZ_CP030848|10|2377284-2377395|CRISPRCasFinder
TTTCCTGGTTCAGAATAGTAGTTAGTAGTTAGTACTTAGTATAAAGACCTATGAAGTCCGATCCTGCCAATCCTTAAATCCTTCCTTTCCTGGTTCAGAATAGTAGTTAGTA

>NZ_CP030848|10|10|2377284-2377395|CRISPRCasFinder
TTTCCTGGTTCAGAATAGTAGTTAGTA	GTTAGTACTTAGTATAAAGACCTATGAAGTCCGATCCTGCCAATCCTTAAATCCTTCC
TTTCCTGGTTCAGAATAGTAGTTAGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526009.1\|2389896_2390910_-\|DUF4974-domain-containing-protein	unknown	unknown	gnl\|CDD\|379829
NZ_CP030848.1\|WP_149526007.1\|2385060_2386743_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|369630
NZ_CP030848.1\|WP_149525995.1\|2369751_2370732_+\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|369561
NZ_CP030848.1\|WP_149525998.1\|2371821_2372556_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378271
NZ_CP030848.1\|WP_149525997.1\|2371432_2371825_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372725
NZ_CP030848.1\|WP_149526012.1\|2391957_2393220_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_CP030848.1\|WP_149525996.1\|2370983_2371331_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319937
NZ_CP030848.1\|WP_149526000.1\|2373293_2373686_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526010.1\|2390985_2391498_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP030848.1\|WP_149525999.1\|2372546_2373287_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777
NZ_CP030848.1\|WP_149525994.1\|2368480_2369488_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224525
NZ_CP030848.1\|WP_149526002.1\|2374410_2376693_+\|catalase/peroxidase-HPI	unknown	unknown	gnl\|CDD\|237891
NZ_CP030848.1\|WP_149526006.1\|2382584_2385056_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526001.1\|2373743_2374136_+\|ribonuclease-inhibitor	unknown	unknown	gnl\|CDD\|240166
NZ_CP030848.1\|WP_149526004.1\|2379744_2381649_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|378963
NZ_CP030848.1\|WP_149526011.1\|2391611_2391863_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149525993.1\|2367496_2368288_-\|TonB-dependent-receptor-plug-domain-containing-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149526008.1\|2386754_2389859_-\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149526005.1\|2381635_2382592_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527696.1\|2377808_2379632_-\|carbon-starvation-protein-A	unknown	unknown	gnl\|CDD\|224877

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526007.1\|2385060_2386743_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.77964e-51
NZ_CP030848.1\|WP_149525995.1\|2369751_2370732_+\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	3.27118e-82
NZ_CP030848.1\|WP_149525998.1\|2371821_2372556_+\|hypothetical-protein	gnl\|CDD\|378271	pfam09844, DUF2071, Uncharacterized conserved protein (COG2071). This conserved protein (similar to YgjF), found in various prokaryotes, has no known function.	1.391e-05
NZ_CP030848.1\|WP_149525997.1\|2371432_2371825_+\|hypothetical-protein	gnl\|CDD\|372725	pfam13781, DoxX_3, DoxX-like family. This family of uncharacterized proteins are related to DoxX pfam07681.	2.131e-13
NZ_CP030848.1\|WP_149526012.1\|2391957_2393220_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_CP030848.1\|WP_149525996.1\|2370983_2371331_+\|VOC-family-protein	gnl\|CDD\|319937	cd08349, BLMA_like, Bleomycin binding protein (BLMA) and similar proteins. BLMA also called Bleomycin resistance protein, confers Bm resistance by directly binding to Bm. Bm is a glycopeptide antibiotic produced naturally by actinomycetes. It is a potent anti-cancer drug, which acts as a strong DNA-cutting agent, thereby causing cell death. BLMA is produced by actinomycetes to protect themselves against their own lethal compound. BLMA has two identically-folded subdomains, with the same alpha/beta fold; these two halves have no sequence similarity. BLMAs are dimers and each dimer binds to two Bm molecules at the Bm-binding pockets formed at the dimer interface; two Bm molecules are bound per dimer. BLMA belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. As for the larger superfamily, this family contains members with or without domain swapping.	2.1943e-29
NZ_CP030848.1\|WP_149526010.1\|2390985_2391498_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	9.27353e-32
NZ_CP030848.1\|WP_149525999.1\|2372546_2373287_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.62581e-09
NZ_CP030848.1\|WP_149525994.1\|2368480_2369488_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.18757e-91
NZ_CP030848.1\|WP_149526002.1\|2374410_2376693_+\|catalase/peroxidase-HPI	gnl\|CDD\|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NZ_CP030848.1\|WP_149526009.1\|2389896_2390910_-\|DUF4974-domain-containing-protein	gnl\|CDD\|379829	pfam16344, DUF4974, Domain of unknown function (DUF4974). This family consists of uncharacterized proteins around 340 residues in length and is mainly found in various Bacteroides and Parabacterodies species. The function of this protein is unknown.	6.73375e-11
NZ_CP030848.1\|WP_149526001.1\|2373743_2374136_+\|ribonuclease-inhibitor	gnl\|CDD\|240166	cd05143, Barstar_SaI14_like, Barstar_SaI14_like contains sequences that are similar to SaI14, an RNAase inhibitor, which are members of the Barstar family. Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell. The sequences in this subfamily are mostly uncharacterized, but believed to have a similar function and role.	5.38881e-10
NZ_CP030848.1\|WP_149526004.1\|2379744_2381649_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|378963	pfam12831, FAD_oxidored, FAD dependent oxidoreductase. This family of proteins contains FAD dependent oxidoreductases and related proteins.	5.56031e-119
NZ_CP030848.1\|WP_149525993.1\|2367496_2368288_-\|TonB-dependent-receptor-plug-domain-containing-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	1.71612e-84
NZ_CP030848.1\|WP_149526008.1\|2386754_2389859_-\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP030848.1\|WP_149527696.1\|2377808_2379632_-\|carbon-starvation-protein-A	gnl\|CDD\|224877	COG1966, CstA, Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms].	1.34533e-180

>NZ_CP030848.1|WP_149526002.1|2374410_2376693_+|catalase/peroxidase-HPI
MENGSNDISKCPFHNGSMNKIKVAGDGTSNQEWWPNRLKIELLRQNSNVSNPMDADFNYAKEFESLDLAAVKKDLHDLMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRVGDGRGGAGAGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGKKISWADLLILTGNVALESMGFKTFGYAGGREDVFEPELDVYWGSEKTWLGGDVRYSHGSEGVEEAHGVLSADDDADGKIHSRDLENPLAAVQMGLIYVNPEGPDGNPDPLAAAKDIRDTFGRMAMNDEETVALIAGGHSFGKTHGAGPADNVGKEPEAADMELQGLGWKSSFRSGVGADAITSGLEVTWTTTPTQWSNNFFENLFSYEWELTKSPAGAHQWVAKDAEDAIPHAFDPNKKQRPTMLTTDITLRVDPEFEKISRRFYENPDLFADAFARAWFKLTHRDMGPSSRYLGPEVPTEELIWQDPIPAVNHPLVNADDVAALKANILNSGLTIAEMVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEVNNPAQLQKVLNTLEGIQTAFNNGQADGKKVSLADLIVLAGATGIVEAAKRAGVQITVPFTPGRMDASQEQTDIESVGYLEPIADGFRNYKKARYTVSTEELLIDKAQLLTLTAPELVVLLAGMRVLETNYDGSKHGVFTNRPGQLTNDFLVNLLDMNTAWEAVGPDKELYQGRDRKTGAVKWTGTRNDLLFGSNSELRAVAEVYASADANDKFVKDFVAAWHKVMNADRFDIKK
>NZ_CP030848.1|WP_149526001.1|2373743_2374136_+|ribonuclease-inhibitor
MKKEIIFDGFAIHNKKSLFEEINRAIMSDEDWEIGESLDAINDILYGGVGKIKGNEPIRLIWKNFEANKELFGKEFTIDFYKEKLKHPEVFDTESIQATLDELENGNGQTYMDILLEIIADHPNIELVKA
>NZ_CP030848.1|WP_149526000.1|2373293_2373686_+|hypothetical-protein
MEVHINIVGALLIMLATIHIIFPRYFNWKNELAGLSLINRQMMQVHTFFLAFILFLMGILCLSSASDLVSTSLGKRICLGFSIFWGLRVLFQFFIYSPKLWRGKVKETIIHILFTLLWIYFTLVFLFVSI
>NZ_CP030848.1|WP_149525999.1|2372546_2373287_+|methyltransferase-domain-containing-protein
MEVSRTAFQGIKNIIRFNWHFYVIAAVSILLLIAISQFLSGILVYFIYATIGFTMLGILASLAVSYYVYDYSDLYQLHWIEKENPKQILSVNAGFDETSDLIKNKKPNTTLSIIDFYNPNKHTEVSIKRARERYPSPKETISVETDKLPFSDKRFDLILCVLSAHEIRDQRERTRFFKELSRVLATEGKLMVTEHLRDTNNFLAFQIGFFHFYSKANWTTVFEEAGLKMKELHKNNPFISTFILTH
>NZ_CP030848.1|WP_149525998.1|2371821_2372556_+|hypothetical-protein
MISLKNHHFAVEAFFERSLVLTFAVPKDELSETIPPCLKLDVYDEQWAFIAVAMVQTKNLKPKGFPKIFANDFFLIGYRIFVKYRDNRGRTLRGLYILKSETDSKRMEFLGNIFTKYSYTTTDIQSIHSDQQETIFSDKSKFSISIAHTDTEIPLPTGSVFKSWKEARRYAGPLPFTFSFDAAKKEVLIIEGVRKDWNPKPIAVVKHQLDFLEKLSLSQYQLANAFAIYNIPYYWKKGRIEKWK
>NZ_CP030848.1|WP_149525997.1|2371432_2371825_+|hypothetical-protein
MKSLPIYSILQGLIALVWLINGLLCKILNLVPRHQQIVERILGEPHARLLTILIGIAEIMMVVWILSRWNARLCAITQIVVIGVMNIIELILAKDLLLWGRLNIVFAFAFMVLIYLKEFRLKPTKNNSSS
>NZ_CP030848.1|WP_149525996.1|2370983_2371331_+|VOC-family-protein
MLTNIHPKIPMRDMRISKAFYIDQLGFNQVGGDYEGYLMIKKDQIELHLFEFKELIPEENYRMIYVRTDNIDALYQQYLQKNISIHPNAPLQQKPWGKEFSILDPDSNLITFGEQ
>NZ_CP030848.1|WP_149525995.1|2369751_2370732_+|alpha/beta-hydrolase-fold-domain-containing-protein
MAIKAEKDPKISKDIRAFLKELNSSGGKPMEEMTPEEARKVLEDAQKSVEVDVSGIIEKEMEISKDGLTVKSIVIKPSDKKDEKLPVFIFIHGGGWVLGDYPTHKRLVRDLVVHSGAAAVFVDYSRSPEAKYPTAINEIYAVTEWVAEHGDEIGVDGKNLAIAGNSVGGNMSAVTCLMAKDKGGPAIKFQLLLWPVTDADFNRASFKEYAEERFLTANMMKWMWDNYLPEEEKRKEYYATPFNAPLDKLKSLPPALVQLAENDILYDEGLDYARKLDEAGVPTLIQTFNGFIHDFGLLNPLDHIPAVKFATELAALGLKKALFGTK
>NZ_CP030848.1|WP_149525994.1|2368480_2369488_+|substrate-binding-domain-containing-protein
MYKPITIKDIAQALAISPSTVSRALSDSYEINEETKKRIIQYAEKHMYKRNPNASSLRRGRSYTIGVVVCEVANSFFSQVISGIESVAYSKGYHVILSQSHDSYEREVLNIQHLANSSVDGLLISMSAETMDFSHIVDLHTRGLPFVFFDRIINEFETHTVTANNKEGARQATQSLIDRGYKNIAHLANAPHLSITKERLEGFKQALQQNDLPFDKSLVRYCVSGGRNQQEIEEGVGYLSNHDREVDAIFVASDRLSMGCIQAYHQVKPLDPPPAIAGFSNSDTLNMLYRDFTCIRQPAFEMGRAAMEKLIHLIESRHPVYSFDKIVLETEMIIN
>NZ_CP030848.1|WP_149525993.1|2367496_2368288_-|TonB-dependent-receptor-plug-domain-containing-protein
MIKRTINFRGVPIVVLFMMIGFLSFAQERIIRGKITDMEGNALEGVSIKLKDIAGAGTLSANDGSFSLEASSDAKVLQISNVGYNSKEINIAPSESFLTITLEATTQDFEEVVVVGYGAMKKRDLTGAVASVNAKDLNTIPAGNPLEALQGKISGVDIGAVTSPGSAPRIRIRGNRSLNASNEPRYVVDGIPRNSIDDIPVNDIESMEVLKDAASTAIYGSRGANGVVLVSTRRAKANSPTSISYNTYVGMNRARFPNMMSGE
>NZ_CP030848.1|WP_149527696.1|2377808_2379632_-|carbon-starvation-protein-A
MNALTLIFASLLIFAIAYRFYGIFLANKVLRLNAKITTPAVEFADGQDYVKTDKKVLFGHHFAAIAAAGPLVGPVLAAQFGYLPGALWILIGCVLGGGVHDMVVLFASVRHKGESLATIASKEISKPIGTIAGLAVLFILILTLAGLSLACISAMHEAPWSLFTIILTMPIAIIMGLIMRYREGSVTFASILGGVLLIVGIISGHNLMEMPAIANLFNWSIGTISIAIAVYGFFASVLPIWLLLVPRDYLSTYLKIGTILMLTVGIIFVAPTIQMPAFTSFIHGGGPVIGGPVLPFIFIVIACGAISGFHAIIATGTTPKMLGNEREILFVGYGAMLVEGFVALMALIAACTLMPGDYFAINTPVAAYDQFLAMHPELHAVDLQHFIDRIGIDLHGRTGGAVSLAVGMAHIFDKVPFMDNVMAYWYNFAIMFEAVFILTAIDAGTRVGRFFLQEMLGSVIPAFKDKNWWPGVILCSAIFTFSWGYLVYTGNVSSIWPLFGISNQLLAACGLIVCTTMLIRMNRKKYALCAAIPGIFMAIITFWAGYVQVKDIYLPNEQYLLASLAGIAMLLMGIVFIGTFIRWSQLFKVKELKVDMYGEEVKELVER
>NZ_CP030848.1|WP_149526004.1|2379744_2381649_-|FAD-dependent-oxidoreductase
MKNNRRDFLKAIGIGSGALLVDPVIAKSLSEKQIIESELKGPESVFAIRNLETDYLVAGGGMAGFCAALAAARNGLKVILIQNRSRLGGNASSEIRMHICGSTALGQVWRETGLLEEVMLTESHINPQRCWEMLDYVMYDKIVSNPNITLLFDSMLYNVKTKGKKIDEIQAYCSQTEEIYNVKAKYFADCTGDGTLAALAGAEFMRGREAKSEYNEALGLDVRDDITMGNSLLFQSQKHDKPMPFKAPSWARKYEFSDFKHRRIHSWEYGYWWIELGGLENIVHDGQKIRHDLMAVVFGVWDYIKNSGNHPESANWALSWFGSIPGKRESRRITGDYVMTQNDILKQENFEDRVAYGGWPLDDHLPAGMDDTSLSPFRSIALKGPYSIPLRSLYSKSFDNLMMAGRNVSVSHIALSTTRVMATCATMGQAIGTAAAFCVKENLTPRKLYENKAKLKEYQQILLRQDQAILKVKNEDNLDLARQAKVTASSELAGFEAKKVIDGYNRDVQDGDSHQWRASLASGEQYIELSWSKPQNLKSVEFTFDSGLNRHLRLSGEASVMKNQKRGRQPEMLMDYNLELYNGSTLVKKEEVTENILRKVVHSFDGISADRVRLVAKKAQEDENARVFEIRCYA
>NZ_CP030848.1|WP_149526005.1|2381635_2382592_-|hypothetical-protein
MNRILLIVAIVGCNLFNVAAQSWTALSKEQEPVLTHTVNDTLSFPVFVVEDPSTKTLYYGTQLQTNVCNDQICLPIVVNLFWDLLGNYHHFSKEEDFHFTKFDHQYFDQKDYERLQGILIDSLSPLRDYDVEDLLDKDGKKYSLEIDAVTKPTSPLFSNVTVPGALYTVYTLWHIVNGPIKQELHALANQQYQKRNWQSYFAKSEIPVYQEYFLKHLEPTEATKYKEEIINLLFAQDDFIPHYAIDVLEADVLKDPNQYNSILKQLDRMKPHVITEIINSISAANEETKSILTAFRATEKASPKQKELIAKILNYEKQ
>NZ_CP030848.1|WP_149526006.1|2382584_2385056_-|hypothetical-protein
MIKENIKILFLGISFLSSNLLFAQQKSFSGIYPNLAMYNDEGECGTGAVVPWNDKLYVITYGPHLPIGSSDKLYIIDKSKKQHVYEGSVGGTPANRMIHKETNSLFIGPYVIDNKGVVTTISPFDMPGRHTGLARHLTDPKKKIYFATMEEGFYEYDLTSKKITELYTDVNLKSESYLKKLPKYQNKKQNFADLFGAHGKGVYSGQGVLVYSNNGESGEKALKQYDIPAGSLSEWDGKSWKLVRRNQFVEVTGPGGIYGNNADNDAIWATGWDHKSVLLAVRDSKKGWSFYRLPKASRSYDGAHGWNTEWPRIREIGDSNGDYLMTMHGMFWKFPKSFTSSNAKGIRPRSSYLKVIGDFAKWNNQLVFGCDDSAQKEFLNKRKIKGNLEGAGQSNSNLWFVDEAQLDYFGSTTAEGAVWINDSLTENLVSEPFLLAGWKKRNIWLKNHNNKPAKFDLEVDLVGNGKWTPYKSINVAANHSISEEMPVDIKGEWIRIKVSDSGNYSAMFSYQGENLAIKELDLFNNLSKIGDNEYLGAYLYALGNNQRKLGVLSGKIQGETFNTTGYYELNSDMELKPVNNSGTVEIIKKNFEIPNDLVSVEESSVLVVDDLGRRWRFPKSKAAFDKLTRNGLTRLAREVATERDLMNLHGTFFELPAENADGFAKVRPIASHDMAIHDFASYRGLLVLSGVNPKGDQDNIIRSEDGKAAVWVGAIDDLWKLGKPTGKGGPLSNTSVKANEVSDPYLFGFYDKRNIELSHNLQEAVDFKIQLDPSGNGEWFDYKTVKVLGNKSEHFVFPSNVEARWMRVILNKACKASAILTYE
>NZ_CP030848.1|WP_149526007.1|2385060_2386743_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKSKIIYLVLSLFLFSCQKLDLNPLSQGSSETWNSDADELIMSLNDLYREALWIKDVDDWTDDWIYRDGLTDITNATINGQSAFVTSGWQNTYKAIARANTVLEGMDRAADILPESQINGYKAEARFVRAAMYSFLLSHYRNVVYLDKTLSIEEAKTIGQMNPDELLKKIYEDFDFAITHLKSSYSSSEVKRATKGAAMALKARIALYMGDFATAKEAASACIALGLYNLHSDYSALFLSKTKQSPESIFLLPRSITLGVALGDRQNYIPRNNGGWAAKDPSWDLFFSYYCTDGLPVDESPLFNPKNPFENRDPRCEATIVPFDQPFLDIIYTPHPLALKTKRVSTGQEITNNDNRAVAQYASFNGLVWRKGVDSDWLLNSWRIEPDNIIIRYADVLLIYAEAKIELNEIDQSVLDAINQVRARAYKVDKSSTNYPKVTTTAQAELRKILRSERRMEFALEGLRYMDIIRWKIAEKVLNKPNFGLLDPADLVSKVVNTGKWFLPTAPPIDEDGSPDFSGFYSQGLIKQIAIRKFDAKKQYIWPIPSTEVLTSGLNQNPNY
>NZ_CP030848.1|WP_149526008.1|2386754_2389859_-|SusC/RagA-family-TonB-linked-outer-membrane-protein
MTMKSKVIYPLLIYGLSSLFQEALAQTNVRANGKVISIDGAAIPGATIEVIDVKTKKKETLGSNDQGLFTLNNLSIDGLYNIYVHHVGFQRDSITNFVAKTNQTNSILIRLKPDDNELDEVVVIGYGTVQKKDLTGAISSVDGKDIAVRKTTQLSQALQGAVPGVMATRNNNAPGAAATIRVRGITTITDGGLNPLVILDGVPISGLDQVNPNDIENVTVLKDAASASIYGSRAAAGVILITSKRGKEGVLSLEYNTDIGWESPTELPEYVGAQRYLQLVNELRWNDNNNNQNEYPIYAKDLVDNYLNLNKENPNLYPITDWQSILLKDRAGRQAHQLSVSGAGKNLRTRFSLGYDDTDALYVMRNYERLTSRINNNIDVTDYLSAVVDLNFKRTTDNRPSIDPLYRMGITAPIYAGMWDDGRTASGKDGDNIYGMLTQGGQTKYQYTQFGGKVGIDLKPIEGLTLTGVIAPIFNFDRTKAFRTKVPYTAWNNPEQRLGYINGYETTKLTESRVESYQYTTQFLGNYMKSLGKHNLNLLAGYEFFYYYNEDLSASRDQYLLSGYPYLDLGPLEFRDNSGSAYENAYRSYFGRAMYNYANKYFIQANIRYDGSSRFAKEYRWGVFPSVSAGWSISEENFMKDVSWLNFLKLRASYGTLGNERIGNYPYQSLIQFSNTALFYTGNQVTSQQSASQWQYAIRDITWEKTESYDVGLDFVGLNNRLNATFDVYNKITSDMLLALQIPVFIGFENPNQNTGKMNTKGWELAVGWKDNINKLTYGLSFNISNFKSVMGDLGGTEFLGNQVKMEGSEFNEWYGYLSDGLYQTADEVAGSPVLNANVKPGDVKYKDVSGPDGVPDGIISPEYDRVFLGGSLPQYLYGGQLNLGYGGLSLNVVIQGVGKQNVRQTTDMIQPYQQNWGNFLSILDGNTWSKYNTDAQNLSAKYPRYSNTSATNNYAMSDFWMINGRYFRLKSVNVSYQIPENFLAKYHVKGLGLSFTANDIFTINKFPKGWDPEMTSFTYPITSSFLFGINVKF
>NZ_CP030848.1|WP_149526009.1|2389896_2390910_-|DUF4974-domain-containing-protein
MKKEILEKFLSNQCSYNECKDVASYLEGNDDELDKIQLFENLADNEIIHIDQVEKDLLCDAILAKPKQGLLLKRLLIAAAVLLFVAFSFYKLGKHDSPSHLESPLLVEIVNDTESAEWHILPDSSRVKLSPAAKLTYRTNFAKDRELNQVAGEITYFVHANKDLPFRVINQGVQTRAVGTTFSIDDYNNENLIIKLLEGKIVVEDPTDNTDSEIILNNPTAIVVSKVNFTYNHINENKEGHKKAWDKERKSIRNNYSESTIAWSNQVVNFSGVSNADLFSIMERLYGVSIDVENPKITNGNFTGELYQNDNLENLLTIFCQINGCNFTIKDNIIRIK
>NZ_CP030848.1|WP_149526010.1|2390985_2391498_-|sigma-70-family-RNA-polymerase-sigma-factor
MYLQIDEESFRAVFTKYYDRIYSGFYKKTGSYEIAQDLTQQTFIKFWRYRDSYSPELTVEIQLFRKGKLVFIDWLRKESKERQMIDSLKQQEKIPIDELSTDLKDSLQNAINGLSPVRKEVFNMAYIEGYSHKEIAEKLNVSIRTVETHIYKSVQQLRKILALIYIMLHL
>NZ_CP030848.1|WP_149526011.1|2391611_2391863_-|hypothetical-protein
MIEIPSIVTASNIFSEEEINTLKSVKQLPEEQEIDAYQYQPEIQELLNAFIGDESTRRTHQLLKAKELIQRNELLNAWKIILL
>NZ_CP030848.1|WP_149526012.1|2391957_2393220_-|NADP-dependent-isocitrate-dehydrogenase
MSDKITISGSGKLNVPDQVSIPFIIGDGIGPDIWHASVRVFDAAIAKAYNNQRKINWLEVLAGEKAFNETGNWLPEATLDKFKEYLVGIKGPLTTPIGGGIRSLNVALRKELDLYVCQRPTKWYEGVPSPVKHPEKVDMVVFRENTEDIYAGIEFAAGTAEARRIQDFLKDDLSVDYNFTNTTGVGLKFVSEEGSKRLIRAAIEFAIAEGRKSITIVHKGNIMKYTEGAFKNWGYQLAESEFGDKLYTWNQWEKTKEASGADAANAEQKAAEAAGKIIVKDIIADNFLQQILLAPQDYDVVATLNLNGDYISDALAAMVGGIGIAPGANINYKTGHAIFEATHGTAPRFANTDSMNPCSVILSGVMMLDYMGWSEAADAIVQAVAETIKEKTVTVDFYNLMEDATLLKTSEFANKVIEKL

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Crispr_ID: NZ_CP030848_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_11

2500856-2500977

Orphan

Consensus_repeat	Method
GTTTTCAATGGCCATCAAGAACTTTCATGCCTGTTGGTGTTTCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_11

>merge|NZ_CP030848|11|2500856-2500977|CRISPRCasFinder
GTTTTCAATGGCCATCAAGAACTTTCATGCCTGTTGGTGTTTCAATGGAAACATGAAAGTTTTTTCTGAAAGGGTCTGTTTTCAATGGCCATCAAGAACTTTCATTCCTGTTGGTGTTTCAA

>NZ_CP030848|11|11|2500856-2500977|CRISPRCasFinder
GTTTTCAATGGCCATCAAGAACTTTCATGCCTGTTGGTGTTTCAA	TGGAAACATGAAAGTTTTTTCTGAAAGGGTCT
GTTTTCAATGGCCATCAAGAACTTTCATTCCTGTTGGTGTTTCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526102.1\|2503011_2503938_+\|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|225313
NZ_CP030848.1\|WP_149526104.1\|2505369_2507463_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP030848.1\|WP_149526093.1\|2491911_2493435_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240533
NZ_CP030848.1\|WP_149526105.1\|2507488_2508064_+\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NZ_CP030848.1\|WP_149526106.1\|2508126_2508567_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP030848.1\|WP_149526099.1\|2500143_2500734_+\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NZ_CP030848.1\|WP_149526107.1\|2508858_2509170_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526108.1\|2509154_2510918_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|227335
NZ_CP030848.1\|WP_149526103.1\|2503996_2505283_+\|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|366466
NZ_CP030848.1\|WP_149526098.1\|2499071_2499689_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526096.1\|2496254_2497145_+\|DUF3078-domain-containing-protein	unknown	unknown	gnl\|CDD\|378621
NZ_CP030848.1\|WP_149526100.1\|2501001_2501859_-\|aminotransferase-class-IV	unknown	unknown	gnl\|CDD\|376449
NZ_CP030848.1\|WP_149526101.1\|2501884_2502916_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP030848.1\|WP_149526092.1\|2491000_2491927_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|366154
NZ_CP030848.1\|WP_149526090.1\|2488814_2489957_-\|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	gnl\|CDD\|377253
NZ_CP030848.1\|WP_149526109.1\|2510914_2512039_-\|sensor-protein-KdpD	unknown	unknown	gnl\|CDD\|225115
NZ_CP030848.1\|WP_149526094.1\|2493446_2494406_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187549
NZ_CP030848.1\|WP_149526095.1\|2494412_2495540_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
NZ_CP030848.1\|WP_149526091.1\|2489963_2490992_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380311
NZ_CP030848.1\|WP_149526097.1\|2497260_2498922_-\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526102.1\|2503011_2503938_+\|pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|225313	COG2515, Acd, 1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism].	1.95312e-56
NZ_CP030848.1\|WP_149526104.1\|2505369_2507463_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	4.9575e-43
NZ_CP030848.1\|WP_149526093.1\|2491911_2493435_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	7.42825e-13
NZ_CP030848.1\|WP_149526105.1\|2507488_2508064_+\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.33511e-18
NZ_CP030848.1\|WP_149526106.1\|2508126_2508567_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	2.17134e-23
NZ_CP030848.1\|WP_149526099.1\|2500143_2500734_+\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	2.21611e-47
NZ_CP030848.1\|WP_149526108.1\|2509154_2510918_-\|HAMP-domain-containing-protein	gnl\|CDD\|227335	COG5002, VicK, Signal transduction histidine kinase [Signal transduction mechanisms].	3.62903e-58
NZ_CP030848.1\|WP_149526103.1\|2503996_2505283_+\|BamA/TamA-family-outer-membrane-protein	gnl\|CDD\|366466	pfam01103, Bac_surface_Ag, Surface antigen. This entry includes the following surface antigens; D15 antigen from H.influenzae, OMA87 from P.multocida, OMP85 from N.meningitidis and N.gonorrhoeae. The family also includes a number of eukaryotic proteins that are members of the UPF0140 family. There also appears to be a relationship to pfam03865 (personal obs: C Yeats). In eukaryotes, it appears that these proteins are not surface antigens; S. cerevisiae YNL026W (SAM50) is an essential component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The protein was localized to the mitochondria.	2.38154e-05
NZ_CP030848.1\|WP_149526096.1\|2496254_2497145_+\|DUF3078-domain-containing-protein	gnl\|CDD\|378621	pfam11276, DUF3078, Protein of unknown function (DUF3078). This bacterial family of proteins has no known function.	1.52505e-31
NZ_CP030848.1\|WP_149526100.1\|2501001_2501859_-\|aminotransferase-class-IV	gnl\|CDD\|376449	pfam01063, Aminotran_4, Amino-transferase class IV. The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.	4.27407e-52
NZ_CP030848.1\|WP_149526101.1\|2501884_2502916_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.3438e-103
NZ_CP030848.1\|WP_149526092.1\|2491000_2491927_-\|glycosyltransferase	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.45008e-21
NZ_CP030848.1\|WP_149526090.1\|2488814_2489957_-\|polysaccharide-pyruvyl-transferase-family-protein	gnl\|CDD\|377253	pfam04230, PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora.	3.69583e-21
NZ_CP030848.1\|WP_149526109.1\|2510914_2512039_-\|sensor-protein-KdpD	gnl\|CDD\|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	2.21884e-125
NZ_CP030848.1\|WP_149526094.1\|2493446_2494406_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	8.82963e-78
NZ_CP030848.1\|WP_149526095.1\|2494412_2495540_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	2.52312e-65
NZ_CP030848.1\|WP_149526091.1\|2489963_2490992_-\|nitroreductase-family-protein	gnl\|CDD\|380311	cd02062, Nitro_FMN_reductase, nitroreductase family protein. Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.	1.42116e-20
NZ_CP030848.1\|WP_149526097.1\|2497260_2498922_-\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	9.65388e-110

>NZ_CP030848.1|WP_149526099.1|2500143_2500734_+|YceI-family-protein
MKTILTFVASLLFITNAAFAQVKWSVDPAHTNARFEVKHLGIAFVDGSFNTLSGAAETSDSSNFNQAKISFEIDVNSIDTRVDARDEHLKSDDFFNAAQYPKMTLTNGVLTKGKKGQFVLKGDLTIRDVTKPVEFQVTQNNGIITDPWGKTRAGFTATTTINRMDYNIKYNDKLPSGVQAVASDVKIIVNTELVKN
>NZ_CP030848.1|WP_149526098.1|2499071_2499689_+|hypothetical-protein
MSIIEKLASQQGLKDESANINLAIEIVKSGDEIGLRELIQGLDDKRIQNDCIKTIYEIGERNGKLLVPFLSVFIDLLSSKNNRLQWGAMCAINSVTLHIPTEVFASISRLEEAANKGSVITRDNFVKILTKLMGNSEHQEMAFRKLSQQLNNAPANQFPMYAEEIMTTIPKEHVAEFRKILESRMDDLPKESQKKRIDKVLKKLK
>NZ_CP030848.1|WP_149526097.1|2497260_2498922_-|AarF/ABC1/UbiB-kinase-family-protein
MQFNGFQKIKRVGQILKILSKHGFDEIISRSNLDRILPDSFLFWNNHARKIFEDDFNTRIRSAIEELGPTFIKLGQLLSNRPDIIPKDLQEELIKLQDDVMLSEIDLRAVLEEELEIDVDAHFSELELKPIASASIAQVYKARLINGQDVVLKVKRAGIDEIIRADLDFIKDLVQLLQRKYEVIYKMNLYQIVLSFESSLLNELSFTNELNNIERFRRNFAGNKDVYVPKVHRKYSTDRILCLEFIDGVKVNDLEGFHSYGLYTKSVLQNVLDLYLEQVLMHGFFHADPHPGNVLINRRGQVVFLDFGAMGFMIPEDRNIIEAMVLDFLANDAKSLIKNIKKLAVIHHIEDERRLERDAYEIFEMIKQNALDDIDISVMLQKLNIVLQSNHILLPDFVYILLRGVSILEGTGRQLDADLNVPESIEPFAKKIAQDKLSADYLIQQLKEKAKFAKDVLTEVPVDLLELLDKVKNDKVTLNHKMQDFDNLQLILHRMGNKFLLSILAMTFGVGASILAHGRVGYLLWGIPVLSWIGFIASFIICFALLNHLYKSK
>NZ_CP030848.1|WP_149526096.1|2496254_2497145_+|DUF3078-domain-containing-protein
MNLLKLVSLSFATVFTLNASAQEATVPAADTTKTWTIKGENAFLINQSSFSNWAAGGINSLAGNLIFNYDFNYKKDKWSWDNKVLAAYGQTFQKETDWRKNDDRFAINSLLGYQAAEKWLYTFFLNFNTQFANGYEYDGKNIVDTISKSFAPAYLSFGPGIAYKASDNFRVNLSPAAARFIIVGDKSLRPLYSVDVDKWSRNEFGASLDAYYKVKLMENIALENILKLYSNYLQDPQNVDVDYTANLSMQVNKLISVNAAAQLIYDDNIDVPKSDGTKGPGLQVRQVLGAGVTYKF
>NZ_CP030848.1|WP_149526095.1|2494412_2495540_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MELLVVFIPFILAIVVNRAFIPFIMLVTYKKRLFDPIDSRKIHHRIIPRLGGVSFAPIQCLLLVITMTLVFKTSLVSIDVQSWAFLSHFMMLICGLVILSMVGIGDDLIGIDYKWKFITQILVASLLPLSGLWINDLYGLGFIVKIPFWIGMPLTVFVIVLIINAINLIDGLDGLCSGLVCVSCLVLGTLFIYYGAWVHALFAFITLGVLIPFFYYNVFGTKKRRRQIFMGDTGSMTLGFSVAFMAISFAMNNEFIRPFSEGAIVVAFSTLIIPVFDVARVMLVRWKLGHPIFKPDRNHLHHKFLRAGMTHRTAMIFIICLALFFSVFNIVMVEYISNNVVIVLDILLWIGFHVLFNRLERRKVIAKVQLYINLL
>NZ_CP030848.1|WP_149526094.1|2493446_2494406_-|NAD-dependent-epimerase/dehydratase-family-protein
MNIAIIGGSGFVGTQLISLLQQSRELHVKNIDKQHSKTHSGITTIANVLDAEALKGELAGFEVVILLAAEHRDDVTPTSLYYDVNVQGMRNTLAAMEHNGIKRIIFTSSVAVYGLDKPNPSEDSPKDPFNHYGISKWQAEQVLDEWSKGHRDWNINIVRPTVIFGEGNRGNVFNLLSQIANGKFMMIGKGDNQKSMSYVGNIIAFIQFMLLKMTTGYNIYNYVDKPDFTTNDLVFHTGEIIGKQIPTTRIPYWLGMMGGYGFDVLAFLTRKKLNISSVRVKKFCAITKYDSRKAMGSGFVPPYSLEEGLRRMLKAEFGK
>NZ_CP030848.1|WP_149526093.1|2491911_2493435_-|polysaccharide-biosynthesis-protein
MGSNASIAKNSAFLFVRMLISMGVSFYTSRAILQLLGIEDFGIYNLVAGVIASFSFIANTIISANSRFLSFSIGLNDITQLKKTFSLCVTSSIITALVLVIFCETLGLWWIFNKINIPDAKFFEAQIVFHIAVLNLFFTIVFTPFNALIISFEKMNIYAIVSVVNSLLNLLVVFLLYFNYSGYSNLIMYGALSLVVNLGISGIYYFYSRTKFKVEGFSICFDKELKKIFTYSSWDIYGNLAVTARTSGVAILQNMFFGVVANAGIGIATQVQNLVNQFSSNILFASKPQVIKRYASGDIDGMIDVINKTVLFTSVLLSLVVVPLIVEMDSILIFWLGILPEHTVAFVQWFLLFIFGANISQCLLMGIHATGKVRNSSIINGTLYLFVIPLSYWAFSKDFAIEFPYILNFLFILIGGLLNAFYLKREVRKFDVLAFYRNCVLPIIVISVLNYLLLIGLKSYTGTGFFAIISTFLFSSCFTALWIWFFVFDKGIKEKSLNYLKEKWSKI
>NZ_CP030848.1|WP_149526092.1|2491000_2491927_-|glycosyltransferase
MVKDLVSIITPCYNSRNFLDKLLESVLIQDYPSIEMILVDDGSVDELAEFLKEHDYFNRFEARGFKLYYCRQENMGQAVAINLGLTKYSGEYLTWPDSDDYYYDHSAISSFVNAINMSDVDIIRCYPRHVDQLGNDLGFHIPNFSDDRVFEECLLENNFWFSPICYFFKASNIKKVLDNRIIPSRVGQNFQLYLPLFYFGNLSTLKLDLVNYLVRSNSHSHSKKSYAQALERLDNILELKLQILNEYDLRIEPTLMKSLYKKFKLSYLNVRLEYGRIGEAFLYLTRNLMFSKGAYLMFIKKVFLQRSN
>NZ_CP030848.1|WP_149526091.1|2489963_2490992_-|nitroreductase-family-protein
MSAIKNLIRKILSPILHNRNVENILKKRYLFRNYRDDAEKFHQYASAFNENDILNKEANLILNYHSLEKGMLFNKMKSGYGAYRINNLHKLLADPDVIDNIDRSQIRVAYEVMCKYYELQTFLGYEIEALFSKQQYEAYKSILGKLYNPEFEGVLHWNRSDFYKDIKSDFSKFSNSRKSVRNFTGELVEKRILEQVVELANNAPSVCNRQASKVYILEDKTKIDKVLKIQDGFNGYTGNVRQLIILTNDRRYYYTTGERNQLFIDGGIYLLNLLYALHYFHVANCPANWAKTTKEELPIYDVLDLPKSEKIICLIPIGVSTEEFRTTLSKRRTVDENLFFIN
>NZ_CP030848.1|WP_149526090.1|2488814_2489957_-|polysaccharide-pyruvyl-transferase-family-protein
MKKLAILTQPLKANYGGLIQNFALQSVLKGFGYNVETLSREYHRDAGAFRTLLAKGKNQVLSLLTGKKKKLFSKKEAAYVFSETYRFIREHLAVSRNLYSTSDLKQYFKNQHFSGIVVGSDQTWRPKYSPNIYNYFLDFIEDDSAKGKLAYATSFGSEQWEYTDEETLRCIELSKKFDAISVREESGVTLCKEHLKVESTWVLDPTLLLKASSYIELFKDLNFADRGLFSYVLDRNDEKNRFIEDICRRIKKDQFRKQPIRSIESGPIYDYSKLEDFKYPSLEEWLASFYYADFVITDSFHGTVFSIIFNKPFLSIVNFERGGSRFYSLLKLFQLEHRLVSDINNFNDSLLEEKIEYQRVNEILEIERQKSLLFLKENLK
>NZ_CP030848.1|WP_149526100.1|2501001_2501859_-|aminotransferase-class-IV
MPIQYINFNGSLVPEDMAVLSVDNRAFRYGDGLFETMLWKDGDIRFLDFHIERLQEGLSLLQFEDTGVFDTFFVRNKTEELIRKNNMMGQTLRVRLIVFRMGAGTYGPESNKAGYVLQVERKQDILRDKKLGLIVDLYTDFKKPYSELSKLKSNNALVYVMAGNFRKKHAFDEVFILNQEGNLCEALTSNIFIYYNKVLYTPALTEGCIAGVMRRVVMDIALSEGIEVVEAEIKPDIMKVADEIFCTNATQGIQWVMGYKQKRYFNKISRVFQDRLAAWTYDIEE
>NZ_CP030848.1|WP_149526101.1|2501884_2502916_-|RluA-family-pseudouridine-synthase
MTEDLDLEQDEQELFEHLRIVADKGQAPLRLDKFLMNRVENTSRNRIQNAIDSGSVLVNEKVVKASYKVKPLDLITIVLPDPPRDTEVYPEDIPLDIIYEDDDVLMVNKEAGMVVHPGFNNYSGTLVNALTFHLNQLPTLPGNTGRPGLVHRIDKDTSGLLVIAKSEWAMTYLAKQFFDHSIARKYVALVWGDLKEDGTVRGYIGRNMKDRRIMDMYDDPEKGKWSVTHYKVLKRLGYVTLIECQLETGRTHQIRAHMKSIGHPLFNDESYGGHKILKGTTFTKYKQFVENCFALLPRQALHAKSLGFEHPKSKQFLQFEVPIPEDFRLALEKWENYSTNTQD
>NZ_CP030848.1|WP_149526102.1|2503011_2503938_+|pyridoxal-phosphate-dependent-enzyme
MPIDFPIYSPVQRILHPLFTHHEVEVFIKRDDMIHPFISGNKWRKLKLHIEKIKALSIKTLVTFGGAWSNHLLATAAAGAQFQLATHAFVRGEEINNPVLALCKLFGMQLHFVDRSAYKDKKALFNANFNENNALFIDEGGRSEEGAVGCESIIEELEDTFTDIFVAAGTGTTAAGILKALNTKGLNSTLHCIPVLKGGDFIKQDILDWGIDIDNLTLHTEYHFGGYAKTNPELLQFIKDFVADTGIMIEPTYTGKMMYALFDHIKTGKIQAESKILAIHTGGLTGFLGMYEKFDNLAPVNTLTKTIK
>NZ_CP030848.1|WP_149526103.1|2503996_2505283_+|BamA/TamA-family-outer-membrane-protein
MRVFLITCFLIFISLTTNAQQIEIQDTISNKEQKDTVRNTEELYDIVDLFKDIIPSKKPKDQKPKKRSPISYLPNINYNPSIGAQIGVKAVGGKVLGNQPNTQMSIAAAALSYTTRGIIVGYLIHDIYTPSNKWNIKGNVMVAKAVGLDYGLGMGTALDNPTEEELIINNPDRQRFVNKFTAYTINERIYKQLFPGAFVGAGVFFELKRGLETIGSAENMSPTEIYSRWNNFNPVDINNNGLMLNMQYTTRDNPNSAHKGMYVDVVLRMNQEWMGSEHNAYQLQTDFRKYWQLSSSRPNHVLAFWNFGSYKLGGKLPYVDLPGTSKDPYARSGRGYTMGYFKGLSYFYSELEYRYPILRNQFLSGVVFANVQSTNDQMGTKLFQQWQPAAGAGLRLLFNKATRTNLCIDYAFGKFGQRGLFLGLNDAF
>NZ_CP030848.1|WP_149526104.1|2505369_2507463_+|TonB-dependent-receptor
MFVFSKKSQLPFLALTLAAYNSVAQTTTPDTSLSEIAPIEIKAHFNSQAMLDLTSSARVVSKRLLESQNTNTILSAVNSTPGVRMEERSPGSYRLALRGSMIRSPFGVRNTKVYLDEIPFTDASGNTYLNIVDPVGINHIQIIKGPDGSLYGPNTGGVLRIIPNGLAPQKSNDKSLLLSAGSYGLFQQQLNIKQQVNEKYSFAFSQAFTRSDGYRTQSGMNKKFFQTAHQWNYNEKGQLKFLGLYADLGYETPGGLTEAQYLEDPRQARPAGGPFPSAVDQKAAIYNKTTIGGITHSYQFNKNLRHVIALFGSYTDFKNPFVTNYETRIEKNLGIRTYFSYEDHDIENLQWEMQLGAEGQKGWYDIKNYENHFGEKGTLNYDDHLENFQHFYFYRLRAKIAQRFIAEGSIGLNLNNIDFKQQALNASAIQGSKGFKNSWMPRLGLSYLILPEFALRASISKGYSTPTISEVRSSDNQINQNLNPEDGVNYEGGIRYETKNRRFIADLAAYQFNMKNGIIRQLNAEGAEYFTNAGAMTQKGVEASVLGQIISPDQNFFVRSLILSSNLTFQDYQFRDYKVDDKDYSGNAVTSIPKWIWVNTLALELPKRFEINIFHNHTSSIPLNDANSFYAKKYHLVQAKLAWTTGLMSRYKLQLFVGVDNLLNEKYSLGNDINAMGNRFYNAAADRNYYGGIKLMM
>NZ_CP030848.1|WP_149526105.1|2507488_2508064_+|cyclic-nucleotide-binding-domain-containing-protein
MLNSFRQHIQKYQKISDEQFEAILSYFEVHSLKKKEMIQEVGQTQLYNYFVLDGCLRMYTLHEKGQEITTDFALESWWLCDQKAYLGKIETDCYIQAVENSRILRISRDKEQLLIKEQPYMQIHFLQIYQKAFAAAQFRNKLFKLYSKEEIFIQFNNNFPDFVQRVPQYLIASYLGLTPEYLSEIRKKIFS
>NZ_CP030848.1|WP_149526106.1|2508126_2508567_+|carboxymuconolactone-decarboxylase-family-protein
MKARMNIAELEPSGYKRVLTLENYIQASDLDKTHLELIKIRASQINGCAFCINMHTKDAMAQGETAQRIFLLNAWRETNIFTPEERTILAMTEEVTKIHEAGLTEDTYQAAKTLFNENYIAQIILAIATINVWNRIAITSHTQPEL
>NZ_CP030848.1|WP_149526107.1|2508858_2509170_+|antibiotic-biosynthesis-monooxygenase
MKTITRIWHGITRKEDADIYLNYLTSTGMKDYRSTKGNLSAKVLRRIDHDICHFMTVTEWESTSSIQEFAGEHFQRARYYPEDKKYLLEFEEFVTHFETYDFE
>NZ_CP030848.1|WP_149526108.1|2509154_2510918_-|HAMP-domain-containing-protein
MKIKTKLNIGIGLLFLMILLLAFASTWYVSSLKREADNVLAANYLSVEYARNMLGASDQYSAGDTVALATLRSNLAKQKKNVTELSEKEITTNLELKLNRLLDNPSDPQHASELREELVNLMNVNMAAIVKKNDHTKLLANEAFLLISILGALSFLIAFVLWVNLPSNIADPIKKLTNSIREIAKQNYAQRLYFKGDSEFVDLANSFNSMAERLQEYSNSKLDHILQEKKRVEALVNSMHDPVIGLNDKKEILFINDEALQLIGLSREEVKLKPLQELANASDLIARIVEIPEKTPERQVHALEDNTLNIFVDNKESYFEKQVYAIEIVPTGEQALQHVGEVIILKNITSFKELDVAKTNFIATVSHELKTPIASIQMGLELLNHPKTGELSENQRKLMEGIKDDSERLLRITSELLNMSQVETGNIKLFAQWCNPMPVITYALQATRLQAEQKHIELVTELDEDLPEVYIDEEKTAWVLTNFITNAIRYSAEHSKIIVSLAKKDAKLVFSVQDHGKGIDSSYKDRIFDRYFQIPGSMRSGTGLGLSIAKDFIENQGGSIAVESSVGVGSTFSFSIPTNKNQHYSKS
>NZ_CP030848.1|WP_149526109.1|2510914_2512039_-|sensor-protein-KdpD
MEEQRKSAEYFLNLLKQARRGKFKIYLGMSAGVGKSYRMLQEAHNLLRNGIPVKIGFIETHGRAETDALVTGLPVLPRRKLYYKGNELEEMDVDLILKLKPEVVIVDELAHSNIPGSKNEKRWQDVIELLEAGINVISAINIQHMESLQVELSAYLKMEVKERVPDKVFDMADELVLIDISVEDLIARLKEGKIYHVDKIQTALSNFFQAEHLDLLRELAVKEVASHAIKKHERYHVGAKKRRLERFMVCVSTDERRARNLIRRTSRLASYYHAEWFVLYVQTAKESSDKIALDKQRFLINNFKLATELGGQVIQIKGTDVPSHIVEQVLQMQITTLCIGRPHWSFFRILWTMGLFRKLLKKLEPIEVDLIILS

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Crispr_ID: NZ_CP030848_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_12

2687230-2687325

Orphan

Consensus_repeat	Method
GCAGGATCGGGTGGAAAGTTAAAAGGAA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP030848_12

>merge|NZ_CP030848|12|2687230-2687325|CRISPRCasFinder
GCAGGATCGGGTGGAAAGTTAAAAGGAAAGTTTGTCTTTGAACGAGGAAAGGAAGGATTCGAGGTTGGGCAGGATCGGGTGGAAAGATAAAAGGAA

>NZ_CP030848|12|12|2687230-2687325|CRISPRCasFinder
GCAGGATCGGGTGGAAAGTTAAAAGGAA	AGTTTGTCTTTGAACGAGGAAAGGAAGGATTCGAGGTTGG
GCAGGATCGGGTGGAAAGATAAAAGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526242.1\|2679015_2679957_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211380
NZ_CP030848.1\|WP_149526236.1\|2673732_2674731_+\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|234866
NZ_CP030848.1\|WP_149526248.1\|2690471_2692646_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227662
NZ_CP030848.1\|WP_149526239.1\|2676349_2677255_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381312
NZ_CP030848.1\|WP_149526238.1\|2675603_2676347_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
NZ_CP030848.1\|WP_149526249.1\|2693078_2693480_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	unknown
NZ_CP030848.1\|WP_093097788.1\|2697528_2697720_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP030848.1\|WP_149526246.1\|2687593_2688586_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149526240.1\|2677241_2677916_-\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|223619
NZ_CP030848.1\|WP_149526247.1\|2689905_2690418_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP030848.1\|WP_149526252.1\|2694739_2697253_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319839
NZ_CP030848.1\|WP_149526253.1\|2697793_2698474_-\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319790
NZ_CP030848.1\|WP_149526241.1\|2677918_2678905_-\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|273203
NZ_CP030848.1\|WP_149526250.1\|2693515_2693692_-\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|377942
NZ_CP030848.1\|WP_149526237.1\|2674739_2675354_+\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|224345
NZ_CP030848.1\|WP_149525548.1\|2688802_2689711_-\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526245.1\|2682374_2686796_-\|DNA-polymerase-III-subunit-alpha	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235554
NZ_CP030848.1\|WP_149526251.1\|2693860_2694613_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526244.1\|2681952_2682270_-\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_CP030848.1\|WP_149526243.1\|2680004_2681873_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526242.1\|2679015_2679957_+\|hypothetical-protein	gnl\|CDD\|211380	cd10981, ZnPC_S1P1, Zinc dependent phospholipase C/S1-P1 nuclease. This model describes both the bacterial and archeal zinc-dependent phospholipase C, a domain found in the alpha toxin of Clostridium perfringens, as well as S1/P1 nucleases, which predominantly act on single-stranded DNA and RNA.	3.70702e-66
NZ_CP030848.1\|WP_149526236.1\|2673732_2674731_+\|tryptophan--tRNA-ligase	gnl\|CDD\|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	9.421e-156
NZ_CP030848.1\|WP_149526248.1\|2690471_2692646_-\|hypothetical-protein	gnl\|CDD\|227662	COG5368, COG5368, Uncharacterized protein conserved in bacteria [Function unknown].	4.68532e-30
NZ_CP030848.1\|WP_149526239.1\|2676349_2677255_-\|aldo/keto-reductase	gnl\|CDD\|381312	cd19086, AKR_AKR11C1, AKR11C family of aldo-keto reductase (AKR). Bacillus subtilis uncharacterized oxidoreductase YqkF is a founding member of aldo-keto reductase family 11 member C1 (AKR11C1). It may function as oxidoreductase. This family also includes Bacillus halodurans AKR11C1, an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.	4.33901e-75
NZ_CP030848.1\|WP_149526238.1\|2675603_2676347_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	6.23298e-127
NZ_CP030848.1\|WP_149526246.1\|2687593_2688586_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	4.09638e-17
NZ_CP030848.1\|WP_149526240.1\|2677241_2677916_-\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	5.95032e-64
NZ_CP030848.1\|WP_149526247.1\|2689905_2690418_-\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	7.55747e-47
NZ_CP030848.1\|WP_149526252.1\|2694739_2697253_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319839	cd07538, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporters. This subfamily contains P-type ATPase transporters of unknown function. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd2+, and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP030848.1\|WP_149526253.1\|2697793_2698474_-\|HAD-IA-family-hydrolase	gnl\|CDD\|319790	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive. This family includes the N-terminal phosphatase domain of human soluble epoxide hydrolase (sEH). sEH is a bifunctional enzyme with two distinct enzyme activities, the C-terminal domain has epoxide hydrolysis activity and the N-terminal domain (Ntermphos), which belongs to this family, has lipid phosphatase activity. The latter prefers mono-phosphate esters, and lysophosphatidic acids (LPAs) are the best natural substrates found to date. In addition this family includes Gallus gallus sEH and Xenopus sEH which appears to lack phosphatase activity, and Escherichia coli YihX/HAD4 which selectively hydrolyzes alpha-Glucose-1-P, phosphatase, has significant phosphatase activity against pyridoxal phosphate, and has low beta phosphoglucomutase activity. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.67471e-43
NZ_CP030848.1\|WP_149526241.1\|2677918_2678905_-\|glycosyl-transferase	gnl\|CDD\|273203	TIGR00661, conserved_hypothetical_protein, conserved hypothetical protein. This model represents nearly the full length of MJ1255 from Methanococcus jannaschii and of an unpublished protein from Vibrio cholerae, as well as the C-terminal half of a protein from Methanobacterium thermoautotrophicum. A small region (~50 amino acids) within the domain appears related to a family of sugar transferases. [Hypothetical proteins, Conserved].	3.08303e-46
NZ_CP030848.1\|WP_149526250.1\|2693515_2693692_-\|addiction-module-toxin,-HicA-family	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	6.21317e-13
NZ_CP030848.1\|WP_149526237.1\|2674739_2675354_+\|deoxynucleoside-kinase	gnl\|CDD\|224345	COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and metabolism].	8.15047e-63
NZ_CP030848.1\|WP_149526245.1\|2682374_2686796_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NZ_CP030848.1\|WP_093097788.1\|2697528_2697720_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.31248e-11
NZ_CP030848.1\|WP_149526244.1\|2681952_2682270_-\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.14195e-49
NZ_CP030848.1\|WP_149526243.1\|2680004_2681873_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	3.37965e-46

>NZ_CP030848.1|WP_149526245.1|2682374_2686796_-|DNA-polymerase-III-subunit-alpha
MYIIFDTETTGLPKRWDAPITDTDNWPRCIQIAWQLHDEMGRMIEHQDYLIKPDGFNIPYDSEKIHGISTALAEEEGIPLTDVLVKFNEALAKAKFVVGQNIGFDINVMGCEFHRYSVDSPMASMPILDTCTEVTAELLKLPGGRGGRFKLPNLTELHSYLFGVPFAEAHNATADVEATTRCFFELVRRNVFKAEELQVDTGYFVEFKQQHPEVVESVGLKHVNLKAASDAIREKTEPAPTVVKIDADTLEALANANFAHLHNHTQFSVLQSTISIDSLVQAAAKQKMPAVAMTDHGNMMGAFHFVNKVLGYNKDLEAKQKEAEEKGEAFDGVPIKPIVGCEFFICENRKDKSRKDNGYQVVFLAKNKNGYHNLAKMASAAYTEGFYYVPRIDREIVEKYKEDLIVLSGNLQGEVPSKLLNIGEVQAEEALLWWKERFGEDFYIEVMRHGQEDENRVNEAIIQLARKHAVKIIATNNTYYVNKADAHAHDILLCVKDGEKLSTPKGRGRGFRFGLPNQEYYFKSSEEMKKVFEDLPEAIINIDEILNKVETYVLAREVLLPKFEIPEEFQHAEDEVDGGKRGENAYLKDLTYKGAARRYAEITDDIRERLDFELATIEKTGYPGYFLIVQDFIAEARNMGVSVGPGRGSAAGSAVAYCLGITNIDPIKYDLLFERFLNPDRVSMPDIDIDFDDEGRGRVMQYVIDKYGSSQVAQIITYGTMAAKSSIKDTARVLDLPLADANEIAKLIPNLKLSKIFNMEDKALKEVLRSEELEAVNRLKGLADGAGLEAETIKQARVLEGSMRNTGIHACGVIITPDDITNFVPVSLAKDSDLYVTQYDNSVVESAGLLKMDFLGLKTLTLIKDTVQNVKLRHGIDLDPEAFDIEDTLTYELFQRGETIGIFQYESPGMQKYMKELKPTVFADLIAMNALYRPGPMEYIPSFIKRKHGIEPITYDVDACEEYLAETYGITVYQEQVMLLSQKLAGFSKGDADVLRKAMGKKQKAVLDKMKPKFIDQAAEKGHNPKVLEKIWTDWEAFASYAFNKSHSTCYAWIAYQTAFLKAHYPAEYMAAVLSNNMNDIKQVTFFMEECRRMGLTVLGPDVNESHYKFTVNEEGAIRFGMGAVKGVGAGAVETIVQSREGEPYKSIFDLAKRVDLRMINKKAFESLAYGGGFDSFSDTHRAQYFYSDSDNPSGIEKALKFAHKFRENENSAQVSLFGAGGAVELPEPSLTPCPQWGLIEKLKYEKDVIGIYLTSHPLDNYKFELRHFCPNNVTDLQLINKAKASEVDQEVLLDFNRIKNKEVVLGGIIALANHRVAKSGKPFGSFIIEDYWDSYEIMVFGEDYVKFKGYLQEGYFVQIRGLVQERFKQVGNWGFELKNIQLLSDLREKMAKSFTIQFPLHVLDTEFMSTLNQLISCTQVEGQEANCQLKFKIMDEQDKLSIEMPVKKRKIFITNEFLDGLEALEGVNYRLN
>NZ_CP030848.1|WP_149526244.1|2681952_2682270_-|thioredoxin
MALEITDSNFEEVVLKSDKPVLIDFWAEWCGPCRMVGPLVDEIATEYEGKAVVGKVNVDNNPDISVRYGIRNIPALLFFKNGEIVDKQIGAVPKSVLAEKLDKQL
>NZ_CP030848.1|WP_149526243.1|2680004_2681873_+|TonB-dependent-receptor
MLSKKLLLLFSITPSFLLAQQNDTTQLKEVIIQENRLLIPFDQRNRNIQIINQEEIQALPSTSINEVLRYAAGVDIRQRGPFGTQADIGIDGGSFDQTLILINGVKLSDPQTAHHMLNLPVPLSEIQRIEILRGPVSRIYGINGLTGAVNIVTKQAESNSVFVQVNGGSSFKKVEEEAGKDGIYYANAVQVGGSFVRKTHQHQLYFGKEHSNGQRYNSGADNEKLYYQNQISIAPDHRIQMMAGYINNEFGANGYYAAPGDKESEELVETVISSISSHHQLNKWYLSPRISHRYNEDDYRYFRHDLSKGRSKHYTQTLSTELHARYQTALGDLGIGAEARFEDISSSNIGKHSRENYGFFTEFRITKFDRFDINVGAYVNYNSDYDWEVFPGIDIGFQATENLRLSVNSGTSQRIPTFTDLYLNQRPGNIGNPDLKSESAWQNEIGLQYSRNKWSFQAGYFYRDISRFIDWLRESTDVPYQAQNLGSNKTHGVYSNLGYKTAFGTDQHMTVNLAYTYLNPSIINDYKNTIIKYGIESLRHQAQATVSYAFRTWSITSANRWLERSSSNSYFVSDLRLAYSKKSISIFADIQNIFDEKYIEVGAVPMPTRWANLGLRYQWVQR
>NZ_CP030848.1|WP_149526242.1|2679015_2679957_+|hypothetical-protein
MKMLFAAVLLIIFAASLQSWGFFAHRTINKHATYSLPADLAPFFKKHLYAITEKAINADKRVYIDSAESTRHFIDLDRYEQLSDSLVVPWFKLNKRLRQHEILMRGIVPWQIDLTYRKLLKAFHEKNAQAIIRQAADLGHYASDAHVPLHTTSNYNGQLSGQVGIHALWETRLPERFMHSYDLYVGKPVYIDNVVEFAWNAVHESHALLDSVFDLEKKVSASMSHRMKKSYVLRNNILMLNYSDEFCERYHEALNGMVERRIRKAIHATASLWYSAWIDAGQPDLSELAPFEINKKDSIPYQRLSPKGREEWH
>NZ_CP030848.1|WP_149526241.1|2677918_2678905_-|glycosyl-transferase
MKILYAVQGTGNGHLTRAIDVIPCLQAHGQVDVLVSGIQADIQLPFEVKYRYHGLSFIFGKSGGVDLWKTFMASTVRKFVKEVNSVPVEDYDLVINDFEPISAWGCYFKEKPCIGLSHQIGAFDPASPKPEEADMLGKFIMKNYAPSTHSYGFHFKSYASHIFTPVIRQSVRQLDPVDNGHYTVYLPSYDDAHLIKQLTRFPDIKWEVYSKHNKRPFKQKNVSINPINSDAFVQSMASASGILCGAGFETPAEALYLGKKLLVIPMKNQYEQHLNAASLEEIGVPVVKSLKKKYEYDMEAWLNAKSRVTVDYPDCTADIVEKIIKKHS
>NZ_CP030848.1|WP_149526240.1|2677241_2677916_-|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MRLILGLLSICFALNTSAQSLKTANDSLSYALGLDVGRNLKQLDFQVNQDVLAKAIKQALDKKDQRFTESQTNEIIRSGLNRLGEEKIAKTKAASQAYLDQNKKKPGVITTEEGLQYQVLQEGTGLHPKPNDMVVVHYKGMLADGTVFDNSYERNEPLDIEIGRTIPGWIIGIPTMKVGGKTRFVIPYDLGYGERSSGPIPAYSTLIFEVELLKIISEEPHESI
>NZ_CP030848.1|WP_149526239.1|2676349_2677255_-|aldo/keto-reductase
MNQSNLSHTDIQIPELSLGAMSLDFKDEKLASYILDQALDLGINYIDTADMYDKGENEKLIGEITKKNRAAWTIASKVGNKWRADGSGWDWAPSKSYILGAVETSLRNLQTDYIDNYQLHGGTIDDPFNEIIEAFELLKEQGKIKAYGISSIRPNVFLKYANETNISSNLMQYSLLDRRPEEYLNLLNEAKVAVFVRGALAQGLLIDKPAKKYLEFTEQEVKAAQEAVNAIAKDLEVPALAVALKYPLLHDAVKSVVVGIRTESQFADLKEAMPAMGKLSLSDYERLLNLLPTIRYTDHRQ
>NZ_CP030848.1|WP_149526238.1|2675603_2676347_+|3-deoxy-manno-octulosonate-cytidylyltransferase
MKVIGVIPARYDSTRFPGKPLVDIGGMTMIQRVYNQVNHASSLSEVVVATDDQRIYDHVKSFAGNVVMTSRNHQSGTDRCAEVIQNISGFDTVINIQGDEPFIDPQQIDLLVSCFSDQEVQIATLIRKITEFADLENVNKPKVVLNAKNEAIYFSRQPIPYFRGKEMKNWLNDAEYFNHIGIYGYRANVLKELTKLPISNLERIESLEQLRWIDNGYKIKTAISSHVNDAIDTPEDLDAIKRKYFNV
>NZ_CP030848.1|WP_149526237.1|2674739_2675354_+|deoxynucleoside-kinase
MHIAIVGNIGAGKTTLTEKLAKHLNFEPQYEAVENNPYLEDFYSDMKRWAFNLQIFFLNSRFRHIVDLQNRQINMIQDRTIYEDAYIFAENLYDMGLMSARDFENYSDIFQSIIHYIKPPDLLVYLKASVPTLVNNIQKRGRDYESGIRLDYLSKLNDKYEKWIGNYKEGKLLVLDKDNLDFANNQEDLGKIIQKIEAELFGLF
>NZ_CP030848.1|WP_149526236.1|2673732_2674731_+|tryptophan--tRNA-ligase
METVVSGIRSTGKLHLGNYYGALSNFVKMQDEYNCFFFIADLHSLTTHPTPQDLNSMVRNVVVEYLAAGLDPEKSTIYVQSDVPEVAELYLYMNMNAYLGELERATSFKDKVRANPNNVNAGLLTYPVLMACDILIHHGVKVPVGKDQEQHLEMTRTFGNRFNRLYNVDYFQEAFAFAYTDKLVKVPGLSGQGKMGKSNGDADCIYLSDTEQAIRKKIMRAVTDNGPTELNQTKPEAVQNLFDLMKVVSTADTVEHFDELYNKCEIRYGDFKKQLAEDMVLATADVRSRIESIGQDDEYIKKVVKMGAEKAAASAQKTIKEVREIIGLKKLF
>NZ_CP030848.1|WP_149526246.1|2687593_2688586_+|transposase
MKKDRITLGVDVSKKTLDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLDPSGKLNSAIFDLKQLISFRKRLVREMAGYKASSSERKAMYGKDAGKAILKVSKTMIDVYKKEIYRVEREILQLIESDESLNRNYQILKSVKGIGPVNAWMTIVYTENFKAFTDPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYAQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149525548.1|2688802_2689711_-|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNTPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVIEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSKVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149526247.1|2689905_2690418_-|OmpA-family-protein
MKRINLLALILISSITFFSCKQQSMVVNPGAVVSKDGTDDGLKNVKREFKDVQQTDEGILVSISSDLLFPTNSSYLSDNAKQELSKLVKVLKDQKAKVRVDGHTDATGTAEYNQWLSDKRAASVKKFLVDAGIADARISTKGLGQSKPIADNKTPEGRQKNRRVEVVILK
>NZ_CP030848.1|WP_149526248.1|2690471_2692646_-|hypothetical-protein
MRFKLIPILLFCLFGLTANAETYPEVVFDNSLVKGTYARSLVDYSGKSWVENVNKHLLVSDTLFFTPGNALSLRYLSHPQGDWNVTIRYSRQKFHYRLSNDDVLSFKLYVGSGNTKSEHLPSISIKQRDNQSVSLAIGNYVQGFKKDAWLDVRIPVKEFAGLNVEEHISGIILRQLNDSKSTHQLFLDQIEFLPANYSKVPLTSAAVLAKATAYGNHVDLQWQVPLTQSIRYVKIYRSEDNKDFVPISIRPTYMQRCLDYVPVLDKKYYYKIAWLDYNYKESPLSAVQEVQPKKISDDELFSLIQIAHINYFVENYDINTGMHMPFRMKEKAIVSVKETGGAILSLMVGVEKNFISRPLFISRVKRIVKFLATAQNKHGFFPSYYDGRKGIPEYFDRRPQYDVESSAAIMEALLVVRQYLKGDDEAEKEIRRGISDIWERMDWKAVTMPYDPQTLRSNLDMLDEYFVSEPIVGVNLGLNAYMLAMASTRSNIPIASFSNAIESKYVSRAEVTSSLLADSTVSDSVRQNSLFPDGIDHGNQDSLYRVSAFQDTIMYGVELPFGAPDGNLLEMYRPFVTINPKLAKLKDYNLAEVVGSYARVVKRRDNEMGVGTSNSDIWGFQQRNDSIGTFRINPAISVASIFLDNQRSIKSLNALYHEFGAFLFSEYGFRSWVDLRSNDVSDEYVASNQANVALLLENAKTGFIWKLYQQIPEIQAVEQRLFKK
>NZ_CP030848.1|WP_149526249.1|2693078_2693480_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MRTLKIIIERSDDMFSAYAENAEGIYGGGDTVEEAKKSILDAIDIMTGEFAAENIPSILKGNYKVIYHFDAESFLNYYKGIFTNAALEKITGINQRQLQHYSSGLKKPRQLQLKKIEEGLHRLAAELQAVELV
>NZ_CP030848.1|WP_149526250.1|2693515_2693692_-|addiction-module-toxin,-HicA-family
MKSSEFHRLLRKNGWIHIRTRGSHYIYEKDGKTYPIPYHGSKEIGEGLRKKIMKDLGL
>NZ_CP030848.1|WP_149526251.1|2693860_2694613_+|hypothetical-protein
MRKIGTKITYKGTPFNPDGDHNIDWGNVNSDEMDYNEAFEDKHSFFLRSEKGMLYGLDKLKFRKKGFLIMEPNPVSFYFSIANDTAMQIQDAYSRLENLLSKNDNSPKLSIAYSYVFKVTSICILFAYTACDAFLNQMIPEYKKIKMDETNKEWSKQEIERLPFEKKLKAVSIYANNYFEKKHPIKLKKLGQLKDFRNRLIHLKEAKQNPILSYNDIYQDILDTDLIKTVKYVKDFINFYKPGLIINYRY
>NZ_CP030848.1|WP_149526252.1|2694739_2697253_-|HAD-IC-family-P-type-ATPase
MTNYNIPKHLKGLSEAEVNTSREKYGINKIETEHSGAWAILWEILKEPMLILLFAISIIYVLVGDYGEALFMFVAIVAVSGISFYQDNRSKKALEELEKLNEPLSTVIRNSQVEKIPSHEIVVGDLCITEEGKMINADGRIVHSNDYSVNEASLTGESFSVFKSADSADKHIYSGTISVSGLAVFEVEAIGKNTKIGKIGESISSIQEESSPLQIQIRQFVKWMAVAGIFIFLLVWGYSYFQSHNFVASLLNGLTMAMSVLPEEIPVAFTTFMALGAWKLMREGVIIKRSSVVETLGSTTVICTDKTGTITENSMHLSKLYDYGSNKIYVETEFDNPKLTTLIDYAMWSSEPVPFDPMEKTLHQVYEKTTRDDQRKQYELFHEYPLEGKPPMMTHLFRNDDGIRIIAAKGAPEAILAVSSLDEVEKDKLRALYKAFGKEGFRVLGVAKSVFPTDDFPEKQQDFEFDFLGFVVFYDPPKKGIENVFKKIYDAGIQVKVITGDNADTTASIAAQAGIVNTAEGLNGSDLAAFSEEQLMSVAERTVLFTRMFPEAKLAVINALKKKGEVVAMLGDGVNDGPALKAAHIGVAMGSKGTEIAKAAAALVITNDDLDKLVLGIAAGRRIYANIKKAIQYIISIHIPIILTVSLPLFLGWIYPQIFSPVHVIFMELVMGPTCSIVYESEPMEKNTMQKPPRSLGDTFLNIKELAISIIQGLAITAGVLFAYQWAIQNGGSEENTRAMVFTTLIFANILLSLVNRSFYYSVFESFKYKNILFPIVIGVTLILLFSILYIQPFARFFEVTALNASELGMSIAIASVSVLWFELYKFVKRKTSTGGK
>NZ_CP030848.1|WP_093097788.1|2697528_2697720_-|30S-ribosomal-protein-S21
MIIVNVKEGESLDRALKRFKKKFEKTGVLRELRSRQAYEKKSVARRIQVKKAIYKQSLNQDNA
>NZ_CP030848.1|WP_149526253.1|2697793_2698474_-|HAD-IA-family-hydrolase
MQLSIFETRKQNFCMQNIKNVILDYGNVIFMIDFKKVSESFSALGITNVNDFFGHRGQDSLFDEFDKGEISAAEFREGVRVKANRPNLTDQQIDDAWNSLLIGVPEGKHEVLEELKKHNRMFLLSNNNELHYAYCMQHIKDRYRVDSNDQFFEKTYYSHLAGLRKPDLAIFELVLKENNLNPAETLFIDDSPQHLEAAKTLGIHTALCTAEHPLEAIVEEYKLLEN

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Crispr_ID: NZ_CP030848_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_13

2810738-2810850

Orphan

Consensus_repeat	Method
TGAACCAGGAAAGGAAGGATACAAGGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_13

>merge|NZ_CP030848|13|2810738-2810850|CRISPRCasFinder
TGAACCAGGAAAGGAAGGATACAAGGATCGGCAGGATCTCACACCATCGGTCTAACTACTAAATACTTACTACTAAATACTATTCTGAACCAGGAAAGGAAGGATACAAGGAT

>NZ_CP030848|13|13|2810738-2810850|CRISPRCasFinder
TGAACCAGGAAAGGAAGGATACAAGGAT	CGGCAGGATCTCACACCATCGGTCTAACTACTAAATACTTACTACTAAATACTATTC
TGAACCAGGAAAGGAAGGATACAAGGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526339.1\|2806880_2807621_-\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|366780
NZ_CP030848.1\|WP_149526345.1\|2813470_2813866_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319911
NZ_CP030848.1\|WP_149526344.1\|2813038_2813452_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176906
NZ_CP030848.1\|WP_149526341.1\|2808685_2809543_-\|NAD-binding-protein	unknown	unknown	gnl\|CDD\|224995
NZ_CP030848.1\|WP_149527711.1\|2811373_2811994_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226851
NZ_CP030848.1\|WP_149526340.1\|2807652_2808660_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP030848.1\|WP_149526334.1\|2800714_2801323_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP030848.1\|WP_149526347.1\|2814326_2814755_+\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|378058
NZ_CP030848.1\|WP_149526342.1\|2809552_2810668_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381378
NZ_CP030848.1\|WP_149526337.1\|2803033_2803882_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP030848.1\|WP_149526351.1\|2816471_2816846_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319925
NZ_CP030848.1\|WP_149526338.1\|2803972_2806435_-\|phospholipase-C,-phosphocholine-specific	unknown	unknown	gnl\|CDD\|274561
NZ_CP030848.1\|WP_149526348.1\|2814832_2815246_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526336.1\|2802387_2802624_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526343.1\|2812323_2812779_-\|ATPase	unknown	unknown	gnl\|CDD\|176910
NZ_CP030848.1\|WP_149526350.1\|2815950_2816397_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319899
NZ_CP030848.1\|WP_149526349.1\|2815387_2815900_+\|SRPBCC-domain-containing-protein	unknown	unknown	gnl\|CDD\|176856
NZ_CP030848.1\|WP_149526346.1\|2813869_2814325_+\|SRPBCC-domain-containing-protein	unknown	unknown	gnl\|CDD\|176856
NZ_CP030848.1\|WP_149526335.1\|2801535_2802384_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP030848.1\|WP_149526333.1\|2799351_2800701_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227041

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526339.1\|2806880_2807621_-\|dienelactone-hydrolase-family-protein	gnl\|CDD\|366780	pfam01738, DLH, Dienelactone hydrolase family.	5.7075e-32
NZ_CP030848.1\|WP_149526345.1\|2813470_2813866_+\|VOC-family-protein	gnl\|CDD\|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.02404e-18
NZ_CP030848.1\|WP_149526344.1\|2813038_2813452_+\|hypothetical-protein	gnl\|CDD\|176906	cd08897, SRPBCC_CalC_Aha1-like_4, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	7.94711e-76
NZ_CP030848.1\|WP_149526341.1\|2808685_2809543_-\|NAD-binding-protein	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	4.54168e-84
NZ_CP030848.1\|WP_149526334.1\|2800714_2801323_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	7.75912e-29
NZ_CP030848.1\|WP_149526340.1\|2807652_2808660_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.42565e-32
NZ_CP030848.1\|WP_149527711.1\|2811373_2811994_-\|hypothetical-protein	gnl\|CDD\|226851	COG4430, COG4430, Uncharacterized protein conserved in bacteria [Function unknown].	2.43335e-29
NZ_CP030848.1\|WP_149526347.1\|2814326_2814755_+\|DUF1801-domain-containing-protein	gnl\|CDD\|378058	pfam08818, DUF1801, Domain of unknown function (DU1801). This large family of bacterial proteins is uncharacterized. They contain a presumed domain about 110 amino acids in length.	1.68227e-18
NZ_CP030848.1\|WP_149526342.1\|2809552_2810668_-\|aldo/keto-reductase	gnl\|CDD\|381378	cd19152, AKR_AKR15A, AKR15A family of aldo-keto reductase. The AKR15 family includes Microbacterium luteolum pyridoxal 4-dehydrogenase (PLD), Pseudomonas sp. D-threo-aldose 1-dehydrogenase (FDH), and similar proteins. PLD (EC1.1.1.107) catalyzes irreversible oxidation of pyridoxal. FDH(EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose. FDH (EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose.	7.35992e-127
NZ_CP030848.1\|WP_149526337.1\|2803033_2803882_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.60514e-15
NZ_CP030848.1\|WP_149526351.1\|2816471_2816846_+\|hypothetical-protein	gnl\|CDD\|319925	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	0.00170968
NZ_CP030848.1\|WP_149526338.1\|2803972_2806435_-\|phospholipase-C,-phosphocholine-specific	gnl\|CDD\|274561	TIGR03396, PC_PLC, phospholipase C, phosphocholine-specific, Pseudomonas-type. Members of this protein family are bacterial, phosphatidylcholine-hydrolyzing phospholipase C enzymes, with a characteristic domain architecture as found in hemolytyic (PlcH) and nonhemolytic (PlcN) secreted enzymes of Pseudomonas aeruginosa. PlcH hydrolyzes phosphatidylcholine to diacylglycerol and phosphocholine, but unlike PlcN can also hydrolyze sphingomyelin to ceramide ((N-acylsphingosine)) and phosphocholine. Members of this family share the twin-arginine signal sequence for Sec-independent transport across the plasma membrane. PlcH is secreted as a heterodimer with a small chaperone, PlcR, encoded immediately downstream. [Cellular processes, Pathogenesis].	2.47323e-118
NZ_CP030848.1\|WP_149526343.1\|2812323_2812779_-\|ATPase	gnl\|CDD\|176910	cd08901, SRPBCC_CalC_Aha1-like_8, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	1.10999e-51
NZ_CP030848.1\|WP_149526350.1\|2815950_2816397_+\|VOC-family-protein	gnl\|CDD\|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	4.47655e-32
NZ_CP030848.1\|WP_149526349.1\|2815387_2815900_+\|SRPBCC-domain-containing-protein	gnl\|CDD\|176856	cd07814, SRPBCC_CalC_Aha1-like, Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Micromonospora echinospora CalC, human Aha1, and related proteins. Proteins in this group belong to the SRPBCC domain superfamily of proteins, which bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. MeCalC confers resistance to the enediyne, calicheamicin gamma 1 (CLM), by a self sacrificing mechanism which results in inactivation of both CalC and the highly reactive diradical enediyne species. MeCalC can also inactivate two other enediynes, shishijimicin and namenamicin. A crucial Gly of the MeCalC CLM resistance mechanism is not conserved in this subgroup. This family also includes the C-terminal, Bet v1-like domain of Aha1, one of several co-chaperones, which regulate the dimeric chaperone Hsp90. Aha1 promotes dimerization of the N-terminal domains of Hsp90, and stimulates its low intrinsic ATPase activity, and may regulate the dwell time of Hsp90 with client proteins. Aha1 can act as either a positive or negative regulator of chaperone-dependent activation, depending on the client protein, but the mechanisms by which these opposing functions are achieved are unclear. Aha1 is upregulated in a number of tumor lines co-incident with the activation of several signaling kinases.	2.12994e-23
NZ_CP030848.1\|WP_149526346.1\|2813869_2814325_+\|SRPBCC-domain-containing-protein	gnl\|CDD\|176856	cd07814, SRPBCC_CalC_Aha1-like, Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Micromonospora echinospora CalC, human Aha1, and related proteins. Proteins in this group belong to the SRPBCC domain superfamily of proteins, which bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. MeCalC confers resistance to the enediyne, calicheamicin gamma 1 (CLM), by a self sacrificing mechanism which results in inactivation of both CalC and the highly reactive diradical enediyne species. MeCalC can also inactivate two other enediynes, shishijimicin and namenamicin. A crucial Gly of the MeCalC CLM resistance mechanism is not conserved in this subgroup. This family also includes the C-terminal, Bet v1-like domain of Aha1, one of several co-chaperones, which regulate the dimeric chaperone Hsp90. Aha1 promotes dimerization of the N-terminal domains of Hsp90, and stimulates its low intrinsic ATPase activity, and may regulate the dwell time of Hsp90 with client proteins. Aha1 can act as either a positive or negative regulator of chaperone-dependent activation, depending on the client protein, but the mechanisms by which these opposing functions are achieved are unclear. Aha1 is upregulated in a number of tumor lines co-incident with the activation of several signaling kinases.	1.95958e-07
NZ_CP030848.1\|WP_149526335.1\|2801535_2802384_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	5.17809e-18
NZ_CP030848.1\|WP_149526333.1\|2799351_2800701_-\|hypothetical-protein	gnl\|CDD\|227041	COG4697, COG4697, Uncharacterized protein conserved in archaea [Function unknown].	0.00386935

>NZ_CP030848.1|WP_149526342.1|2809552_2810668_-|aldo/keto-reductase
MQRRTFIQQGSLLAMSLATIGRASAFADIYEQNQHNQKENFMGKFRPKDKIGMGGVAIGNGFQENPDIECLESMSAAWDAGVRYFDTSPWYGLGISERRMGMFLKDKPKEDYIVSTKIGRILKPHDNFKQEGLMWNGRMNFDYTYDYSSEGTRKSVEDSLQRLGLPTIDIVFIHDLSPDNADMGDDWVKYYDIAKEGAMKELTKMREEGLIKAWGFGVNTIEPILRAIDDSDPDIFLSACQYSLIHHIDDLDKVFPKVAERNMSIVVGAPLCAGFLAGKNRYLYGKEIPEFAAKKLERLKTVAQRHEVDLLAASLQFSAAPDVVSAVIPGAHTVEQVQENVAAFKKEIPKAFWDDLKKENLIAAHAPVPKA
>NZ_CP030848.1|WP_149526341.1|2808685_2809543_-|NAD-binding-protein
MNQTERIGFIGLGNMGHPMAKNLENAGFPLSVYNRSPEKAADFAAKSQVCTDISRLVSESDIIFTMLSNDDAVHAVYETVLQLPIEGKLFVDMSTISQECSTEVAKLLAGSGAGFVDAPVAGSTQPAKDGTLIFMVGSANGYLLKVKPYLDVMGRETLHLGDNGKGIAAKLCINYYLSILYQGMAETVLFAEKMGIAADDMMRIINESASGSGASRVKTPLLVNNEFPAAFALDFMLKDVKLAVNAGADYPMTDTLMKTYQGAHDKGFGEQDVMAVIEYLRKQNN
>NZ_CP030848.1|WP_149526340.1|2807652_2808660_-|alpha/beta-fold-hydrolase
MRYIGYCLTLICCLNFTWLAAQEHRKVLDIRLSTYEYPYPVKELLISSQQQELPMAYMDVPPEGNSKGKIVVLLHGKNFNAAYWKTTIKALTEDGYRVIAPDQIGFGKSAKPERYQFTFQQLAENTKALLDHLKIEKVSLLGHSMGGMLATRFALMYPDLVEKLILENPIGLEDWKLYAPYTSIDKHYAAELKVTYETVKDYQLGFYYDNKWKESYDEWVYLLTGWVKHPDYPRVAYNNAQTADMIFTQPVVYEFDRLEVPTLLIIGTRDRTAIGKNLVKDEKIKASLGQYQILGKMTQSKIKGSVLVELKNVGHLPHIEVFDRFIEPLKMFLKK
>NZ_CP030848.1|WP_149526339.1|2806880_2807621_-|dienelactone-hydrolase-family-protein
MKYATILCLFGMLSSMGGNAQELKSVDYKDGEQKLKGMVTSNAGSTKPGVLILPAWKGIDQEAKTAALDLEKQGYIAFIADIYGVGNTPADNQAASGLSSKYKNDFKLYQSRIQAALTEMKKQGADKVAVIGYCFGGTGALEAARGGLPVEGVVCIHGGLAKAADRPNEAIKAKVLVEHPADDASVKKEDIEQLVNEMNEGKADWQIITYANSKHTFTNPESPDYNEIMAKRAWNHTLLFLQELLK
>NZ_CP030848.1|WP_149526338.1|2803972_2806435_-|phospholipase-C,-phosphocholine-specific
MDTRRDFLRKASLLAGATAATQFMPDSIQRALAIDAPAGSTYLDAEHVVFLMQENRSFDHSYGTLKGVRGFNDPRTITNQGLPIWLQKNAQGKYYTPFHLDIEKTKSTWMGSLPHGWRDMVYARNNGKMNTWLEAKKAGNPNYQHMPLTLGYYNRQDLPFYYAFADAFTVCDQHFCSSLTGTSANRSYFWSGTVREEPRNPESTAHVDNGQINYRDVSWKTYPERLQEAGIDWRVYQNELSVPVGFEGEEEDWLANFTDNNLEFHKQYQVKFHPAYYEYIKKEIPKIEHQLMTSRFASEEAYKKVVNRLEGYKRDVERYSPANFAKLSKQEQEIHKRAFTTNTSDPDYHSLADITYSDSGTERTVKVPKGDLFYQFRKDVEENKLPTVSWLVAPCRFSDHPGSPWFGAWYVSETLDILTKNPEVWKKTIFILTYDENDGYFDHIPPFVPALHTRPETGAVPKGMETADEFVTNEQEKKRSGNNESTLDSPIGLGFRVPLVIASPWSKGGWVNSEVCDHTSTLQFLEHFIQKKTGKKVLESNISAWRRLVCGDLTSVFRKPEDSKRPTIDFVDRDAEVSRIYKAQAKGLPEDFDVLDSLEDAKAISFKKGNNGLQLAEPGTKQACAIPYDIDVNFAVDKANQIFTLIFQVAGQLPAHKVVGVPFFAKSAVPFGERSELDRVFNFAVKPNESIHYKWSFDKFVGDKIDIEVYGPNGFYRRFAFSKKNIPSAVTVIAADHMRGLQLKTSPSAIGLSIEHIAYGHASRQVTKGKTSGHTWNLARSSGWYHMEVTSKEDGQLLLIYAGHQENGKPSMTDPVMGAK
>NZ_CP030848.1|WP_149526337.1|2803033_2803882_+|universal-stress-protein
MKHALLVPTDFSENAWVAAQYAAELAKKYDWSVQILHVYQTFSRLLATQEFKDEVSRHNTNAAEDDMEIFYNRFKTAYPSIDSTAACMEGNLNDIILNLIDENPVKFIVMGTKGASGLVNVAIGSNTYELIRHSPIGVLAVPENYGDFKFEKIGVLTNFKDHDIEILSEFVARTGLSLKISLLHVNEAAKKPSSEDVLFWQEKVMKELGSDEVTYHDYEMVNRLDVREPITYAVERLVEDENIDVLLVSYTRKSFFRSLFSRSLPKIIANKLTVPTYFKKTD
>NZ_CP030848.1|WP_149526336.1|2802387_2802624_+|hypothetical-protein
MQLLIKKLEKEKKLGEKASKYTQIIDEKSVSHGVLFFIPLDKFEAKVLIPAPFHESLFVHGDPTYQQVLNHKEAMMLK
>NZ_CP030848.1|WP_149526335.1|2801535_2802384_+|universal-stress-protein
MRAILFPTDFSDIATNAFVYALHIAKSIDAKIYVLYTYVEPVLSATHAGQPELIGEVYQTIELNQFETYKKKTQGMRTIAESEGASDVELVFLFEEGPVSSVVKKIVEREKIHLVAMGTHGESGFLSKIIGSNTVNVIKNIQNPVLAVPPHAKYQGINRVVFTTLFREKDKPALREAIIMAKAVNARLDCLNILHNSKVGDVMLQTENWRHEFPNEDINYVLLDEVESIENTITTYLLENNIDILAVVKRNRGFFDRMFNNSISNNLAFHSKVPILVFHEEK
>NZ_CP030848.1|WP_149526334.1|2800714_2801323_-|sigma-70-family-RNA-polymerase-sigma-factor
MGILNKYLGNGTPLNLRVALDKCAVSNSEKGKAFLYKKYYGYVMAIVFRYMKHEMEAEELTNECFVKIFTKIESFSIHEDDTVLEKTFKAWIGRIAVNTSIDALRVRKQMYMLDDLNGSDTLHFAVEADSRLEYNDIIALIRELPDIQRTIFNMYEIEGYSHDEIARELSIPESTSRTYLTRAKQKLRKLYATRIDLERIQS
>NZ_CP030848.1|WP_149526333.1|2799351_2800701_-|hypothetical-protein
MESNKNKDIIDHIVRSLKDKEELPYREGAWEKFQSAQFAPKRTKAAYYYWAASAAAALLIAFFAVNNWSEAPVGDNTLTANNSNPTEQTTVVPQLEDSPLETPNDLPSASSLSSGVTSGLLANQTAWQQMSSTNTNTNEHAVGELQLGDLQAAHVAFAPQMMNIPTLKAEGVQIRNVVNLSNAKPVRSGNSGHVMAYQGDQFAMQADGKEPKLGQKKFSFSERFDLGLFVSPSSTNEQMNFGGGMLLGYNISKNLSVRTGLAYNQYEVGLMKDPIGAPETQILASSDVLEQDAKYSMVATQASRTMVLPNVNAVSGNVQAFEIPLEVKYKTNAGLYASTGMTYAVVLNQNRYTHFIENANADLFEKGLPTSSKEMNDAVQPVTRKVKTDEENVNTGNFGGFVNFSIGKEMRVNKRLNLSVEPYVKLPVGSFKQADMNYTNGGIRIITNF
>NZ_CP030848.1|WP_149527711.1|2811373_2811994_-|hypothetical-protein
MVDFNAEKLKDKKVPNWQKNNERWGECIELMHQLIVKTTEPLTKEFKWGTDIYTFQKKNLIGWGAFKDFFSLWFYNGVFLEDKEKVLINASEGKTKALRQWRFTDVKDMDEKKILAYINESIQTIKDGKEIKAEKSAPKAIEGLLKEALESDSTFDLAFKKLTPGKQKEYIEHIDEAKQEKTKLARLEKIKPLILDGKGLHDKYKK
>NZ_CP030848.1|WP_149526343.1|2812323_2812779_-|ATPase
MENALTAKASIQIQKPAHEVFEAIVKPEGMSKYFIESSTGPLENGKTVTWKFPEFEDTFPVTAKHIEKDRYISFDWSGGAEGMLVEMHLQSLPDGSTVVRVVEGSMNNDEEGIKQAIGQSEGWANFLACLKASLEYGINLRKGAFDFMRPE
>NZ_CP030848.1|WP_149526344.1|2813038_2813452_+|hypothetical-protein
MSSKKIHIETLVNAPIQQVWDAYNNPDDIKQWNQASPDWHCPSSENDLRVGGKFKNKMAAKDGSFEFDFEGTYTEVTPLNSISYVMADERTADLKFTEQGDNTLISVDFDAENMNPEEMQREGWQAILDSFKNHVEK
>NZ_CP030848.1|WP_149526345.1|2813470_2813866_+|VOC-family-protein
MKDNEYKLGQIVWADYTSEHADSLKEFYKEVAGWKEHPIKMQDENGEYHDYAMLREENEVAGGICYKRGVNSAIPSQWIMYIYAPDVDERLEKVLSLGGKLIHSNKGKDGKYNFIIVEDPAGAVFGIGRMQ
>NZ_CP030848.1|WP_149526346.1|2813869_2814325_+|SRPBCC-domain-containing-protein
MKTLYFKETIDASPSKVHNLMLSKKSYEEWTKPFSPTSTFQGDWSSGSKIFFVSTDEDKKDMGMIARVETNIPGEIVIIRHIGILSDQGELYEGEHVDPWKNSLEIYRFKAVGNQTEVLCSLEVDNDEYEEMFAAMWPNAMKVLKDICERS
>NZ_CP030848.1|WP_149526347.1|2814326_2814755_+|DUF1801-domain-containing-protein
METLKTSFTDEDVASFIESVDNEQKRKDSYALISLMEKATGEKAKMFGPTIVGFGQYHYKYDSGHEGDAPLLGFSPRKAAISLYVYTGGKRQDELLKSFGKYKMGKACIYVKKLSDIDVEVLEDLMKDSIQFTSEKYQRVKS
>NZ_CP030848.1|WP_149526348.1|2814832_2815246_+|hypothetical-protein
MMHSTNYYNSLITVAEDCKVDQGTIPKENPDKLTVANYHFQMINAEPLALDSDEVIFNTHAIRKDIVAAEREKERDAFFSKGQACLRTSPLAKTYGWGIYFNEEGKMELIDSIGDEYQKLLDDESIKKIPAMRSTKK
>NZ_CP030848.1|WP_149526349.1|2815387_2815900_+|SRPBCC-domain-containing-protein
MENSKDYQFHIDQANNTLLIKRTYPAKLETVWRAFTDAKILDQWWAPKPWKSETKSQEFEEGGKWLYAMVGPEGDKMWSVAEYQQITPQISYKVLDAFSDENGNISNEHPTSTWETKFTSMGDQTEVTNVITFKSSEDLHAILDMGFKEGYEMGQQNLIDWLDENPDIAT
>NZ_CP030848.1|WP_149526350.1|2815950_2816397_+|VOC-family-protein
MAKIHAYLNFDGTCKEAFDFYSQVFSSPVTGTYFYDDMPSEPGSPELPESAKGKVMHTSLALNDTTMLMGSDVVEGFGMKLNNGNATYIMLDAKDAEEARTLHQALSKDAKVMEMELGETFFAEQFSSFEDKFGIYWMIHFEGNKKMG
>NZ_CP030848.1|WP_149526351.1|2816471_2816846_+|hypothetical-protein
MMQQPQFQPGKNMAMKVSLAKYHETVHFYRDILLLDVEEVELNHPQVAKTCKVKINDMILWIDGIENLSQTDLWFEMETDSIQAAMEYLSANNVEKDDSLEQLPPNAHWIKDPVGNIILLRQKA

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Crispr_ID: NZ_CP030848_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_14

2946042-2946148

Orphan

Consensus_repeat	Method
TCTAAAATCTATTGTCTAATGTCTAACATCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_14

>merge|NZ_CP030848|14|2946042-2946148|CRISPRCasFinder
TCTAAAATCTATTGTCTAATGTCTAACATCTAATCCGAACCAAGAAAGGAAGGATGAAAGCAGAAGCAGGATCGGGTCTAAACTCTATTGTCTAATGTCTAACATCT

>NZ_CP030848|14|14|2946042-2946148|CRISPRCasFinder
TCTAAAATCTATTGTCTAATGTCTAACATCT	AATCCGAACCAAGAAAGGAAGGATGAAAGCAGAAGCAGGATCGGG
TCTAAACTCTATTGTCTAATGTCTAACATCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526456.1\|2939329_2940052_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|365803
NZ_CP030848.1\|WP_149526457.1\|2940522_2941062_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP030848.1\|WP_149526454.1\|2936780_2937035_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527716.1\|2940100_2940535_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182510
NZ_CP030848.1\|WP_149526461.1\|2947143_2947794_-\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	unknown	unknown	gnl\|CDD\|234691
NZ_CP030848.1\|WP_149526460.1\|2946269_2947070_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320690
NZ_CP030848.1\|WP_149526451.1\|2931716_2933195_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|373012
NZ_CP030848.1\|WP_149527717.1\|2953837_2954446_+\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213022
NZ_CP030848.1\|WP_149526466.1\|2951527_2952301_-\|TerC-family-protein	unknown	unknown	gnl\|CDD\|223930
NZ_CP030848.1\|WP_149526452.1\|2933207_2933993_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149526464.1\|2949319_2950855_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
NZ_CP030848.1\|WP_149526458.1\|2941112_2944769_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|341067
NZ_CP030848.1\|WP_149526467.1\|2952331_2952862_-\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP030848.1\|WP_149526462.1\|2947807_2948665_-\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|238806
NZ_CP030848.1\|WP_149526453.1\|2934004_2936575_-\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149526455.1\|2937226_2938852_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NZ_CP030848.1\|WP_149526463.1\|2948737_2949151_-\|DUF4783-domain-containing-protein	unknown	unknown	gnl\|CDD\|379759
NZ_CP030848.1\|WP_149526465.1\|2950838_2951417_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526468.1\|2952858_2953767_-\|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378965
NZ_CP030848.1\|WP_149526459.1\|2944761_2945646_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213231

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526456.1\|2939329_2940052_-\|AAA-family-ATPase	gnl\|CDD\|365803	pfam00004, AAA, ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.	9.9112e-33
NZ_CP030848.1\|WP_149526457.1\|2940522_2941062_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.54011e-20
NZ_CP030848.1\|WP_149527716.1\|2940100_2940535_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182510	PRK10514, PRK10514, putative acetyltransferase; Provisional.	6.68851e-39
NZ_CP030848.1\|WP_149526461.1\|2947143_2947794_-\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	gnl\|CDD\|234691	PRK00220, PRK00220, glycerol-3-phosphate 1-O-acyltransferase PlsY.	4.94237e-65
NZ_CP030848.1\|WP_149526460.1\|2946269_2947070_-\|M48-family-metalloprotease	gnl\|CDD\|320690	cd07331, M48C_Oma1_like, Peptidase M48C, integral membrane endopeptidase. This subfamily contains peptidase M48C Oma1 (also called mitochondrial metalloendopeptidase OMA1) protease homologs that are mostly uncharacterized. Oma1 is part of the quality control system in the inner membrane of mitochondria, with its catalytic site facing the matrix space. It cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Oma1 can cleave the misfolded multi-pass membrane protein Oxa1, thus exerting a function similar to the ATP-dependent m-AAA protease for quality control of inner membrane proteins; it cleaves a misfolded polytopic membrane protein at multiple sites. It has been proposed that in the absence of m-AAA protease, proteolysis of Oxa1 is mediated by Oma1 in an ATP-independent manner. Oma1 is part of highly conserved mitochondrial metallopeptidases, with homologs present in higher eukaryotes, eubacteria and archaebacteria, all containing the zinc binding motif (HEXXH). It forms a high molecular mass complex in the inner membrane, possibly a homo-hexamer.	2.09391e-83
NZ_CP030848.1\|WP_149526451.1\|2931716_2933195_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|373012	pfam14322, SusD-like_3, Starch-binding associating with outer membrane. SusD is a secreted polysaccharide-binding protein with an N-terminal lipid moiety that allows it to associate with the outer membrane. SusD probably mediates xyloglucan-binding prior to xyloglucan transport in the periplasm for degradation. This domain is found N-terminal to pfam07980.	1.30641e-30
NZ_CP030848.1\|WP_149527717.1\|2953837_2954446_+\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	5.61313e-57
NZ_CP030848.1\|WP_149526466.1\|2951527_2952301_-\|TerC-family-protein	gnl\|CDD\|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	6.32714e-73
NZ_CP030848.1\|WP_149526452.1\|2933207_2933993_-\|hypothetical-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	3.91808e-34
NZ_CP030848.1\|WP_149526464.1\|2949319_2950855_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_CP030848.1\|WP_149526458.1\|2941112_2944769_-\|ABC-transporter-permease-subunit	gnl\|CDD\|341067	cd09604, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains bacterial M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	6.38601e-29
NZ_CP030848.1\|WP_149526467.1\|2952331_2952862_-\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	3.67145e-80
NZ_CP030848.1\|WP_149526462.1\|2947807_2948665_-\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|238806	cd01572, QPRTase, Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. QPRTase functions as a homodimer with two active sites, each formed by the C-terminal region of one subunit and the N-terminal region of the other.	2.64286e-137
NZ_CP030848.1\|WP_149526453.1\|2934004_2936575_-\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	1.09084e-133
NZ_CP030848.1\|WP_149526455.1\|2937226_2938852_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP030848.1\|WP_149526463.1\|2948737_2949151_-\|DUF4783-domain-containing-protein	gnl\|CDD\|379759	pfam16022, DUF4783, Domain of unknown function (DUF4783). This family of proteins is found in bacteria. Proteins in this family are approximately 130 amino acids in length. There is a single completely conserved residue F that may be functionally important. Recent structures show this domain has an NTF2 fold.	3.53099e-25
NZ_CP030848.1\|WP_149526468.1\|2952858_2953767_-\|helix-hairpin-helix-domain-containing-protein	gnl\|CDD\|378965	pfam12836, HHH_3, Helix-hairpin-helix motif. The HhH domain is a short DNA-binding domain.	4.94991e-17
NZ_CP030848.1\|WP_149526459.1\|2944761_2945646_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	5.43339e-111

>NZ_CP030848.1|WP_149526459.1|2944761_2945646_-|ATP-binding-cassette-domain-containing-protein
MNLTISNLNKTYSNGVKALDNVNLTIGPGMFGLLGPNGAGKSSLMRTIATLQTPDSGDITFGDIDILSDKNALRRVLGYLPQEFGVYPNLSAEELLNYFANLKGISAKADRQKIVTEVLQVTNLYDVRKKSVSGYSGGMKQRFGIAQMLLNNPKLIIVDEPTAGLDPAERHRFLNVLREIGAQHTVIFSTHIVDDVRELCHELAIMNGGRVLFRGSSEEGEKQLNGKIWTKRVERSEFDAANATHNIISSNYNQDNTLNIRVMSDVQPDESFRSVSPILEDVYFVALKNDSINV
>NZ_CP030848.1|WP_149526458.1|2941112_2944769_-|ABC-transporter-permease-subunit
MFSTIFTFEVTRWFKQPVFYVYCVIYFALAYFTTIAALGAFDAVSATTSTPVYVNSPLNIAGFFNSFSTLIYFLLPTIIGAAVYRDYLYHVHNLLFSYPLDKLSYLSAKFLSALLVVSFVAILTILGYYMAQFHPGIDKSMLGPNRIEAYFSGFLLVVLPNFLLFGSIIFALVTFSRNIYVGFVFVLILLLLQSVLDIATQDADNRYLVALLDPFGFQPITYYTKYWSVEEQNNNLLPMSGVMLYNRLIWTGLAVLILGLVYYKFSFSQLGISFTRSKSSERVTKNNFGSIIKIDLPKVGISHSFFSNLKLSWRLSHIDFKYVVKNWTFIILLLIAALFVLAVMSVGGMLYGTVTYPVTWQVLQTMGGIYSFFLVIMILLFAGMLIQRDQQSNMKLLIDSTSVPNWVLLTSKYIALMKMTIVVLIISMLTGIIYQTYNGYFKFEIGHYLYELFILDYLKYLVLIGFALFIHGFFRNYFVGFIVCLIIVLGIPFLSRIGIEQAIYKFNNGASYHYSDMNGYADIRHYLYYRLYWLLFTGVLFALTLLFWRRGIISNVKDRLQQFALRFKAPIVIPALLSLIAFVGLGYAIYYVNNVVSTRYSNKEKELQQVDYEKKYRHFQDLPMPRLVSVFAKVDITPKDRHLKAEGNFVYVNKTEQPIDSMFMRFNGSVKTEVKLDRQIKNTVKDSILEVNIYHLQEPLMPGDSLKIKYQLTSLSNTFLMDRSLILENGTFFNNSVFPSLAYEDGVELVDNRVREKYKLAPRDRMADPRDSSKLRNTYISKDADWIDFEAIVSTSPDQIAIAPGYLQKEWEENGKKYFHYKMDSPILNFYSFISAKYEVKKEKVNGKNMEIYYHKGHDYNLDRMMASIKKSLGYYESNFSPYQFNQLRIIEFPSTHGTFAQAFANTVPFSESIGFIAKVDDENPNAVDYPYSVVAHEFAHQWWAHQVIGANVKGATMMSESLSEYSSLKVLEHTYGKGQMRKFLKDALDQYLMGRASEQLKENPLMLNENQQYIHYNKGSLVMYAMSDYLGENAFSSMLKEYIAKTAFQNPPYTTSIEFVDVLRKHTPDSLQYLIKDMYETVTLYDNAIENASIKPLKDGKYEVSMDFKVSKYRTDEKGKRSYEDVKGTKLSEKMKDSDKRSVESLPLRDYVDVAIFGSPKKQGKYEHEHALLEKRVKVDRIKNRLTFVVNEKPIAVGVDPYNKLIDTDSNDNRHTF
>NZ_CP030848.1|WP_149526457.1|2940522_2941062_-|GNAT-family-N-acetyltransferase
MNVNLQPVLEHEQYLLLPLQADDFEELYAVASDPKVWEQHPNKDRWRRDVFTNFFEGALNSGGAFKVIDKDSMAVIGCTRFYDREPLDDSIHIGYTFYATNYWGSGANHAVKRMMLAYIFPYVSKVLFHIGAENLRSQISIERLGAIKIDEKEVAYYGEGIKKNFVYLIEKSNWQKLEG
>NZ_CP030848.1|WP_149527716.1|2940100_2940535_-|GNAT-family-N-acetyltransferase
MRGVIERYESQDYRILVDIWESAVKATHHFLKEEDFLFFKDAIPNEYLPHLEVYVFKEESILGFMAVNEHHLEMLFVDDAFRGRGIGKQLLNYAVEELGVKSVDVNEQNEQAVVFYQRHGFKVSSRTEQDSLGKDYPVLLLVIE
>NZ_CP030848.1|WP_149526456.1|2939329_2940052_-|AAA-family-ATPase
MNIQDLIIKDKEPVNLNDVFLSEENRLQIQQLIKEQLYVDDLQQYGLPVNNKVLLFGSSGCGKTTTAKAIANAVERPLIVLNLSNIINSRIGETSQNIKQVFDRAIRDKAVLFLDEFDQIGKARGEDENDVGEMRRLVNTMIQLIDYLPEQVMLICATNHIDIIDFALIRRFQLKISFEMPSNEVLDAYYDKLLVRFPNELQQIERRYNISFAEAKDYTYTLVKAKLIAALEGRHQKIVD
>NZ_CP030848.1|WP_149526455.1|2937226_2938852_+|ATP-binding-cassette-domain-containing-protein
MINVSNLSLRYGKRVLFEDVNLKFTPGNCYGIIGANGAGKSTFLKIISGEVDPSTGSVSFTPGERMSVLNQNHYAFDEFPVIQTVMMGNQELFKVMKEKDEIYMKDPFTDADGERAGELESLFAEMDGWNAESNAATLLSNLGIKEDLHYKQVKELDGNEKVRVLLAQALFGNPDILILDEPTNDLDINTIAWLEDFLASYEAIVLVVSHDRHFLDAVCTHIVDIDFSKMSIYSGNYTFWYESSQLALKQRADQNKKMEDKVKELQEFIRRFSANASKSKQATSRKKALDKINIDEIKPSNRKYPAIMFNMMDREPGDQILNVEGLSKTKNGEVYFKDITFMMNKGDKIAVLAENNLVTSAFYDILTGRDQDYKGEFKWGVTITPADMPIDNAAFFDGKDENLVDWLRDYTTKPDADEQFIRGFLGKMLFSGEEVLKKCSVLSGGEKMRCMFSRMMLQGANFLIFDEPTNHLDLESITALNNGMNDFKGSMLFTSRDHELTQTVANRIIELTPNGIIDKLMSYDEYINSDAVKAQREQMYK
>NZ_CP030848.1|WP_149526454.1|2936780_2937035_-|hypothetical-protein
MTERITEFLLENYLSDGCSKAEMKRVEEYVNSVEGKLHLDEYLDKVWEAASKERVDEDVLDECRGLFLMEVAKENHFEERNGRK
>NZ_CP030848.1|WP_149526453.1|2934004_2936575_-|SusC/RagA-family-TonB-linked-outer-membrane-protein
MDLFLIFNKAKSLWITTFSSMLILFLLSSAEANSVGSIDFQRTIKGEVRDQGGKPLSGASVIIKGTSQGVSTDSEGKFTLQVPAGAVLQIRLLGYEGQDITVGARDFISVNMKATSTVLDDVVVTGYQVVSKRQFTGASTKINTEDVRRDGIADVSRMLEGQVAGVSVQNVSGTFGAAPKIRVRGATSISGDNKPLWVVDGMILEDIVNISNEQLSTGDPATLIGSSVAGLNPDDIESFEILKDAAATSLYGARAMNGVIVITTKKGRVGTPLVSYTGNFSTYLKPSYSQFNIMNSHDQMSMYAEMQRKGWLNYGQTSRFANGGVFIKMADLINQYNESNGQFGLKNDPASRRAFLERYANANTDWFDVLFDNSLMQEHALSVSMGTEKGQLYVSTSYLNDNGWSKADAVQRYTGNVRATFTPSKRLNFGIIAQGSIRDQNAPGTLGRTSNQVTGSFDRDFDINPFSYALNTSRVLTAYDEKGNLEYFRRNFAPFNILNELEYNNIKLNFIDFKMQGDLRYNILNNLKFSFEGAYRYAVTNQEHNIHENSNIPNAYRADADATIRESNRFLYRDPDNPEAEPIVILPYGGFYNTDDVNMVSYNLRNSLDYNVKLAEDHKLNSYAFMELRSADRKFKVFNGYGYQFDKGGVPYVDPKFLKMMVEANANYFEMSKRKERFLAYGLNSRYTFKDRYNVAGTVRYDGSNLMGRTNTARWLPTWNLSASWNIDGEEFFQRQSFINTATLRASYGLTASSGPATNSSVVLRNRAANRPYLTERESVIGIANVENSELTWEKMYKANIGFDMAMWNNRLTLTMDYYDHDSYDLIGRIRTGGIDGEALKLANYADMEAYGVEGP
>NZ_CP030848.1|WP_149526452.1|2933207_2933993_-|hypothetical-protein
MNKSDWKWDTQFNFGYNKAKITNLRNEPNIWSLVNTDGGAMVGYPQRGLFSLDYRGLDQKQGMPKFINEKGEESPEVFLQDLNTSHLVYGGSIDPLLTGGFFNGFQYKNIRLTALVTFSTGNVVRLRPAFRSSYTELDATPDEFLNRWLMYGDDAEPSILDRRENSDIIGSYPYNNYNYSTRRVAKGDFIRLKQVMLSYNLPQNLLKTSTLKSASLSLVANNLWLIYSDKDLNGQDPEFFGSGGVAMPIPRQFTLSLKLGI
>NZ_CP030848.1|WP_149526451.1|2931716_2933195_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTINKIIIPSAILFLGLLPSCNKFLDVNPDMRTEINSVEKVAELLATAYPQANYISFTEGMSDNAGDKGAGTVEIVNSAPYRFEDVADINMDSPTYYWNAAYAAIAAANHALEAIQKAGDDPAYIPYKGEALVARAYAHFMLVNFFAQPYDATNAAANPGIPYVTEVGKVVIGKYERSTVAETYNKIEKDLLEGLPLLDNAAYKKAPKYHFTVAAAHAFATRFYLFKKDYQKTIEHANQVFVGGDIASSLRAINSEAYRSFQYYELQAQYTRADNPANLLMAEAPSIWGRFYPVYRYSLTTDIMNELFTTSNVTDGSWAYNIYGRETSLNIPKFREHFVRQTLNAEIGTPYNIIPLFTAEEVLFNRAEAYAELAKYDNAIQDLNDFASKRIIHSPSIPIYVPELHSITDRNLLEFYKTADLKRAIVQCVLDFKRVDFIFEGQRWFDIIRHKLPVTHRTTDNEILILGVNDPMRVFQIPQEAQSSGLALNPR
>NZ_CP030848.1|WP_149526460.1|2946269_2947070_-|M48-family-metalloprotease
MKRIFKYTAMLMLGASIAGCATSAITGRKYLKLVDSQQINDQAALAYKDFLSKNNSKVVTGTAAATQVKRVGSNIAVAANQYLKQLGLADKFNFNWEFNLIESPDVNAWCMPGGKVAVYTGILPVAKNDAGLATVMGHEIAHAIEEHSVSQYSNAMAAQYGAQILGAAGAMSNSKYIGIFNQLYGIGYQVGSLRFSRNDELAADKAGLILMAMAGYDPNESIKFWERMAQGKSGNPPEWLSTHPSDARRIAQLQAMIPEVMKYYKK
>NZ_CP030848.1|WP_149526461.1|2947143_2947794_-|glycerol-3-phosphate-1-O-acyltransferase-PlsY
MISIYLVGIVILAYLFGSIPTAVWFGQAFYGVDVREYGSGNAGATNTFRVLGKKAGSVVMFVDILKGWTATNLPYLLDSSVVGNHDAPQFVNFQLALGVIAVLGHLFPIFAGFRGGKGVATLFGMVLAIHWPAALCCVTVFLLVLFIFHYVSLGSILAGFTFPFSIAFIFKTTVPSVLLYGIAICALILVTHQKNIERLLKGKESKIYLFKKKSSG
>NZ_CP030848.1|WP_149526462.1|2947807_2948665_-|carboxylating-nicotinate-nucleotide-diphosphorylase
MEKEFKEKLLQFVEDAIREDVGPGDYTTLSTIDETKQGEAQLLVKESGIIAGIEVAKEIFLAIDPNLHFEIFLKDGDAVKYGDIAFRLKGAIHTILKGERLVLNVMQRMSGIATQTAKYVAAIAGTKARVLDTRKTTPLLRFLEKKAVELGGGVNHRFALYDMILIKDNHVDYAGGITAAVNSALSYKSEHNLDIPIEVEVRNFEELKEVIAIGKVDRVMFDNFRPAQVKEAVDLVNGQLVTEASGGITLDTIAEYAKQGVDFISVGALTHSVKSLDLSLKAKLI
>NZ_CP030848.1|WP_149526463.1|2948737_2949151_-|DUF4783-domain-containing-protein
MIHHLKISCRPLLYICYALLILPLLSFTISYNDVGNEIMEAFKSNNAKAISNYFGSNVSLSIKSDGGYYSKFQAEMLLSDFFQSNKTSEIKQVQRTSRTNNSFYIVYQLKTSSGTYRVFTKFSQISGETQIAELRIE
>NZ_CP030848.1|WP_149526464.1|2949319_2950855_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSSEQKRVALLILDGLGYGKDDNSNAVLAAKTPYLDYLLATYPNSKLEASGEAVGLPAGQMGNSEVGHMNLGAGRTVYQELGRINKAANEGIFNSDLTLEKAFDYAKENNKKVHFIGLLSDGGVHSHILHLKALCDAAKNAELGNDQVFIHAFLDGRDTDPNGGVGYMRELNQHLVSSVGTVASAIGRYYAMDRDNRWERVKEAYDLLTKGLGTPSTDMVASIEASYANEVTDEFVKPIVMVKPDGTPIATIENGDVVICYNFRTDRGREITIALTQQEFPEYNMHPLDLYYVTMTSYDDTFKGVKVIFQKDNLTKTLGETLSAQHKTQVRIAETEKYPHVTFFFSGGREEQFEGESRILIPSPKVATYDLQPEMSAQGIADAICEDMQVNHPDFICLNFANPDMVGHTGVFEAVVKAVEKVDSVTKQVVDQGLKEGYSFIILADHGNSEFMLNEDGSVNTAHTTNLVPCILIDNEYKHIKNGKLGDVAPTVLKMMNLEIPLEMNGDVLVY
>NZ_CP030848.1|WP_149526465.1|2950838_2951417_+|hypothetical-protein
MYWFTKNLSKKLALATGLAFALHACSSPESEQKADQKAEVYFDIPSFIQNEIDSLKQANPSVNKTVTKDKEEETKDLKIKDWDNEFSSFKSIDLNKPAYAGFIELDTVDSVVEYNFTNPDLDLACVRIAFDEQGKVKMLSVDKHVKNTLYQTSEFLVYEKGNFYIVEKNQKVRVMGENYYKVQGNLKSDKAL
>NZ_CP030848.1|WP_149526466.1|2951527_2952301_-|TerC-family-protein
MEWLLDPNIWISFLTLTILEIVLGIDNIVFISIQSAKLPVEQQKKARQIGLLLALVMRVGLLFSIKWIMGLTEPFLNLADTLGIEDPQWHRYLTLSGRDLILFIGGLFLIYKATTEIHHKVEGHIEASSGRSKTVTFSSVIIQIIILDLVFSLDSVITAVGMVDQIGVMIAAVIVAVGIMLLSAESISKFVNDYPSVKMLALAFLLLIGVSLTAEAFDQHIPKGYIYFAMAFSVLVEFLNIRAEKKALEQLEKEKNN
>NZ_CP030848.1|WP_149526467.1|2952331_2952862_-|adenine-phosphoribosyltransferase
MIEDQLKAVIRDIPDFPKPGIVFKDITPLLQHSELVELAVQEFARRLENIEFDVIAGIESRGFLFGFLLAQYMKKPFIPIRKQGKLPYHTVSESYKLEYGQATIEMHEDAFPKGTKVLLHDDLLATGGTVVAASKLIEKVGGSVAGYTFVISLDFLQSAGRLTRFNENIISLVGYQ
>NZ_CP030848.1|WP_149526468.1|2952858_2953767_-|helix-hairpin-helix-domain-containing-protein
MNRLFAYFRMRREEQIGFSILAVLIVILLFCTFLYDRVPKKKMLSTEVRALAEDLVSSPDVRYENSRVSKLGETTKSKPAISYFFFDPNGLSVDEWKRLGLSERKIRVIHNYEAKGGHFRKPEDVAKLYSLTDEDVARLLPYVRIAEKEFKRTNFERPIAKKAFTAPYESLRINLNTADSAELTQLRGIGPAFSRRIVRFRELLGGFYSTEQLSEVYGLPEETFLHIKQHLQVDEASIVKLKINDLDANALSRHPYISYKQARTIVNYREHHGAFSSMDDLKKILSLDEAFFRKIEIYLDFK
>NZ_CP030848.1|WP_149527717.1|2953837_2954446_+|polysaccharide-deacetylase-family-protein
MHIVRPLFILPYLYSNAIWRLKEEKNNIFLTFDDGPIPEITPWILDCLKERNVKACFFCVADNVRKHPDIFQRILAEGHQVGNHTYNHLKGWNTDDSIYLANVEKADQLINSPLFRPPYGRIKKSQLREVSKKYRVIMWDVLTGDYDKRISPDQCLQNAVNYTRSGSIIVFHDNIKAIENVQYALPRAIDQLLAKGYNFASL

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Crispr_ID: NZ_CP030848_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_15

3096145-3096255

Orphan

Consensus_repeat	Method
TTTGAACCAGGAAAGGAAGGATGCGAGGATGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_15

>merge|NZ_CP030848|15|3096145-3096255|CRISPRCasFinder
TTTGAACCAGGAAAGGAAGGATGCGAGGATGATCAGAATGTGCGTTGTCTTCGAGCCAAGAAAGGAAGGAAAATTTGTCTTTGAACCAGGAAAGGAAGGATGCAAGGATGA

>NZ_CP030848|15|15|3096145-3096255|CRISPRCasFinder
TTTGAACCAGGAAAGGAAGGATGCGAGGATGA	TCAGAATGTGCGTTGTCTTCGAGCCAAGAAAGGAAGGAAAATTTGTC
TTTGAACCAGGAAAGGAAGGATGCAAGGATGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526587.1\|3105478_3106306_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|131480
NZ_CP030848.1\|WP_149526580.1\|3096759_3099771_+\|protein-translocase-subunit-SecDF	unknown	unknown	gnl\|CDD\|237276
NZ_CP030848.1\|WP_149526584.1\|3102374_3103148_-\|TIGR02757-family-protein	unknown	unknown	gnl\|CDD\|378237
NZ_CP030848.1\|WP_149526586.1\|3104206_3104776_-\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NZ_CP030848.1\|WP_149526588.1\|3106504_3107335_-\|patatin	unknown	unknown	gnl\|CDD\|132866
NZ_CP030848.1\|WP_149526570.1\|3085141_3085972_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226145
NZ_CP030848.1\|WP_149526575.1\|3089840_3091091_-\|L-fucose:H+-symporter-permease	unknown	unknown	gnl\|CDD\|340952
NZ_CP030848.1\|WP_149526578.1\|3093902_3095378_-\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|376340
NZ_CP030848.1\|WP_149526585.1\|3103190_3104189_-\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237048
NZ_CP030848.1\|WP_149526582.1\|3100934_3101936_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NZ_CP030848.1\|WP_149526579.1\|3095588_3096056_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526572.1\|3087006_3087771_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|212491
NZ_CP030848.1\|WP_149526571.1\|3085984_3086839_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP030848.1\|WP_149526577.1\|3092334_3093453_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP030848.1\|WP_149526573.1\|3087826_3089491_-\|altronate-dehydratase	unknown	unknown	gnl\|CDD\|377287
NZ_CP030848.1\|WP_149526581.1\|3100311_3100938_+\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239264
NZ_CP030848.1\|WP_149526583.1\|3101932_3102367_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
NZ_CP030848.1\|WP_149526576.1\|3091226_3092084_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP030848.1\|WP_149526574.1\|3089496_3089829_-\|L-rhamnose-mutarotase	unknown	unknown	gnl\|CDD\|377501
NZ_CP030848.1\|WP_149526589.1\|3107459_3108065_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526587.1\|3105478_3106306_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	2.39471e-43
NZ_CP030848.1\|WP_149526580.1\|3096759_3099771_+\|protein-translocase-subunit-SecDF	gnl\|CDD\|237276	PRK13024, PRK13024, bifunctional preprotein translocase subunit SecD/SecF; Reviewed.	0
NZ_CP030848.1\|WP_149526584.1\|3102374_3103148_-\|TIGR02757-family-protein	gnl\|CDD\|378237	pfam09674, DUF2400, Protein of unknown function (DUF2400). Members of this uncharacterized protein family are found sporadically, so far only among spirochetes, epsilon and delta proteobacteria, and Bacteroides. The function is unknown and its gene neighborhoods show little conservation.	8.54969e-123
NZ_CP030848.1\|WP_149526586.1\|3104206_3104776_-\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	9.52002e-77
NZ_CP030848.1\|WP_149526570.1\|3085141_3085972_-\|amidohydrolase-family-protein	gnl\|CDD\|226145	COG3618, COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	2.25641e-47
NZ_CP030848.1\|WP_149526575.1\|3089840_3091091_-\|L-fucose:H+-symporter-permease	gnl\|CDD\|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.59063e-133
NZ_CP030848.1\|WP_149526578.1\|3093902_3095378_-\|IMP-dehydrogenase	gnl\|CDD\|376340	pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain. This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains pfam00571 are inserted in the TIM barrel. This family is a member of the common phosphate binding site TIM barrel family.	0
NZ_CP030848.1\|WP_149526585.1\|3103190_3104189_-\|GTPase-ObgE	gnl\|CDD\|237048	PRK12299, obgE, GTPase CgtA; Reviewed.	0
NZ_CP030848.1\|WP_149526582.1\|3100934_3101936_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	6.49177e-161
NZ_CP030848.1\|WP_149526588.1\|3106504_3107335_-\|patatin	gnl\|CDD\|132866	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6. Bacterial patatin-like phospholipase domain containing protein 6. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. This group includes YCHK and rssA from Escherichia coli as well as Ylbk from Bacillus amyloliquefaciens.	5.80121e-67
NZ_CP030848.1\|WP_149526572.1\|3087006_3087771_-\|glucose-1-dehydrogenase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.24897e-72
NZ_CP030848.1\|WP_149526571.1\|3085984_3086839_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.04119e-98
NZ_CP030848.1\|WP_149526577.1\|3092334_3093453_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	1.33087e-19
NZ_CP030848.1\|WP_149526573.1\|3087826_3089491_-\|altronate-dehydratase	gnl\|CDD\|377287	pfam04295, GD_AH_C, D-galactarate dehydratase / Altronate hydrolase, C-terminus. Family members include the C termini of D-galactarate dehydratase (EC:4.2.1.42) which is thought to catalyze the reaction D-galactarate = 5-keto-4-deoxy-D-glucarate + H2O, and altronate hydrolase (altronic acid hydratase, EC:4.2.1.7), which catalyzes D-altronate = 2-keto-2-deoxygluconate + H2O. As purified, both enzymes are catalytically inactive in the absence of added Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of altronate hydrolase activity is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre, but the function of the single bound Fe2+ ion is unknown. The hydratase has no Fe-S core.	0
NZ_CP030848.1\|WP_149526581.1\|3100311_3100938_+\|redoxin-domain-containing-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	5.18374e-06
NZ_CP030848.1\|WP_149526583.1\|3101932_3102367_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	2.35318e-11
NZ_CP030848.1\|WP_149526576.1\|3091226_3092084_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.09828e-24
NZ_CP030848.1\|WP_149526574.1\|3089496_3089829_-\|L-rhamnose-mutarotase	gnl\|CDD\|377501	pfam05336, rhaM, L-rhamnose mutarotase. This family contains L-rhamnose mutarotase which is a glycosyl hydrolase that converts the monosaccharide L-rhamnopyranose from the alpha to the beta stereoisomer. In Escherichia coli this enzyme is the product of the rhaM gene (also known as yiiL). The tertiary structure has been solved, in complex with L-rhamnose, and the catalytic mechanism determined. His22 is the proton donor. The enzyme naturally exists as a dimer.	2.93805e-35
NZ_CP030848.1\|WP_149526589.1\|3107459_3108065_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.64643e-12

>NZ_CP030848.1|WP_149526579.1|3095588_3096056_+|hypothetical-protein
MKKTLLSLAAAAALAFGANEAQAQTPYKTAIGLGIDLGDGPSLFGPQIKHSFGGANAGQAQVLFGDHFTVIGVDYSYNRPFGGTNGLGWYVGVGPQIAFANDDSAFAIRPAAGLEYKIPSAPLALHFDWKPWWNLSDNSNFEAGRFSLGFKFTLR
>NZ_CP030848.1|WP_149526578.1|3093902_3095378_-|IMP-dehydrogenase
MQLDPQKFVSEGLTYDDVLLIPAYSEILPRDVDTSTFLTKKIKLNIPLVSAAMDTVTGADLAIAIAQAGGIGMLHKNMSIAEQAAEVRKVKRSESGMIQDPVTLLENATVGDAFQIMSEHKIGGIPVINQENRLVGIVTNRDLRFQKDMARPISELMTKTNLVVAPEGTDLIKAEEILQNHKIEKLPVVDSNGVLKGLITFKDIQKYKHYPNAAKDEHGRLLVGAAVGVTHDTVERVDALVKAGVDVITIDTAHGHSLGVINKLKEVKAKYPELQVIVGNIATGDAAKMLADAGADAVKVGIGPGSICTTRIIAGVGVPQLYAVYEVAKALKGTGVPLIADGGIKQTGDIAKAIAAGADTIMAGSLFAGVEEAPGETILLEGRKFKSYRGMGSIEAMEKGSKDRYFQDVEDDIKKLVPEGIVGRVPYKGTLAEVVYQYIGGLRASMGYCGAATIEQLQGARFVRITGAGLRESHPHNIQITKEAPNYNSRG
>NZ_CP030848.1|WP_149526577.1|3092334_3093453_-|IS110-family-transposase
MEKFCGLDVHKDSVFMCILSENNEKYEEVFKTLTPDLERLRDTLVDHGVGLVAMESTSIYWYPLWNILESDFDVKLVNPLFIKQVPGRKSDVKDAEWIATVLMKDLIKGSFVPPSIIQQLRLYNRKITKLNKQLRRSEQEMDEMLQRCNIRLSNYVSDIGCKSMKKVVQAIAKNHLNPDYLLSLVHARIVRKSGAETIRASLTGTFTSVDIEILRMIVEDINFHHDQLEFCKKELLKLCYQHFNLQMELLVTIPGVKEHAAACIISEIGTDMKFFTSATALVGWTGLRPRNDQSAGKIKGRKTLHGNKYLRLMLVQCAWGASRTKGSAFMARYQRFRKRMHHNKALIANARKLLVIIWNILAKKEPYFAQAI
>NZ_CP030848.1|WP_149526576.1|3091226_3092084_+|helix-turn-helix-domain-containing-protein
MIIKHFALPKEPNQSFQIRRDYTPKHQLIWHYHEELELIHVIKGVGTLFIGDCIKSFQAGDSVLIGSQIPHYWMFENNASDTEQTAAIDCIVLHFNKDIGIPNILHAPELGGIKQLINHSNRGLYVSNKNPNRIPFLIEKTLNSSGLSKLTSMLELLDHFAQQNTENLTSENYSILNISDDQGRMNSLMEHIRDHYKQRIKLEELASIAGLTENSFCRYFKQKTGKTPVQFITELRISHACTQLRNSNLSLKEICYDSGFNNFVSFHKNFKNITKVTPTQYRTSS
>NZ_CP030848.1|WP_149526575.1|3089840_3091091_-|L-fucose:H+-symporter-permease
MSKTNNTVAIILITSLFFFWGFIHNLDPILIAHLRSAFSLNHLQASLVDSAVFIAYLVMGIPAGIIMKKYGYKVGILIGLLLFAIGCFLFVPAANTMSYMFFLSALFIVACGITILETAANPYMTVLGDPNTATQRLNFAQSFNGLAAFVAPIVGGQFILAEDPLSAEQVAALSDAERLSYIQAETAVVKGPYVILGCIILAAAIIFMLIKLPEAKEADEEKSSFVKAFRHKNVSWAVLAQFFYVGAQVCILSFLIVFAVEVSGISAQDAKYYAGVAGLVFMLGRFIGTFLMRSIAPSKLLFIYAIIATLLTCVAIFASGVLTLYAMIAIAFFMSIMFPTIFAIGVTGIGSDTKSASSLIIMSIVGGALLPPVLGYVSDATGNMQYGYFVVVICFLVVALFAYKNKSAAVSTAAAH
>NZ_CP030848.1|WP_149526574.1|3089496_3089829_-|L-rhamnose-mutarotase
MFKRYALALDLVDDPQMIAEYEQHHKTVSDEIKKSITDAGITVMDIYRFGNRLFMIMEVDETFDFARKDAMDAANPAVQVWEGLMWKYQQAIPGAKPGEKWVIMDQIFEL
>NZ_CP030848.1|WP_149526573.1|3087826_3089491_-|altronate-dehydratase
MEKKKLAYLQIHPKDNVLVALRDLPAGYEVDFEDKQFPLIEAVAAKHKFTISDMHKDDEVYMYGVLVGKVNYDLTKGSLINVNNLRHASDDFRLGKRNLGWSKPDVSMYKDKTFLGFHRSNGKVGTANHWLVIPLVFCESRNVMTLKNALEEKLGYQVESKDYADEVDVMIAKFQAGASVDELLDVDLSAAKANKSKSRLFENVDGIKFLNHEMGCGGTRLDSDALCGLLAGYITHPNVAGATVLSLGCQHAQASILKEEIQKRDPQFDKPLYIFEQQFEGTEQELMQKAIKATFAGLSLANAHSRQPAGLDKLCIGLECGGSDGFSGISANPALGYVSDMLVSLGGSVILSEFPELCGVEQELSDRCVDEETASRFMSLMKTYNAKAEADGSGFYMNPSPGNIRDGLITDAIKSAGAAKKGGTSPVVAVRDYPEPASQPGLNLLCTPGNDVESTTAEVGSGANVVLFTTGLGTPTGNPIAPVIKVSSNTKIYEKMNDIIDINCGTIIDGEETIQEAAHRILDYVIDVASGEKMAKAVVLGQDDFIPWRRGVSL
>NZ_CP030848.1|WP_149526572.1|3087006_3087771_-|glucose-1-dehydrogenase
MAKLAGKVAIITGGGSGIGRAISELFAAEGAKVHILDLNPDGAAETASVIKQAGGACELHTVNVSNQQEVLAAVAQIGKVDILVNNAGIAHVGNVEHCSEADFDRIYQVNVKGAYNALYAVIPVMKANGGGAILNLASIASVVGIADRFAYSMSKGAIYAMSLSVARDYLHDHIRSNSISPARVHTPFVDGFIAKNYPGQEEEMFEKLSKSQPIGRMAKPAEIAKLALFLCSDDAGFITGNDYPIDGGFIKLNN
>NZ_CP030848.1|WP_149526571.1|3085984_3086839_-|fumarylacetoacetate-hydrolase-family-protein
MKLIRYGESGKEKIGVQIEDRNYDVSAFGGDYNEEFFADNGLARLEDFVKANEGNLIEIPADARLGAPFVRPSKIVCIGLNYKDHAEETGAKIPAEPIIFMKSTTALVGPNDQVMIPKNSLKTDWEVEFGIVIGKKASYVDENEALDYVAGYVLHNDVSEREFQLERGGTWDKGKGCDTFAPMGPVMTTADEIPDINSVRLWLKVNGKMYQDGNTSNLIFNVPFVVSYVSQFMTLLPGDVISTGTPAGVGLGFNPPIYLQPGDIIELGADHLGVQRQEVVAFSK
>NZ_CP030848.1|WP_149526570.1|3085141_3085972_-|amidohydrolase-family-protein
MRIDAHQHFWLYDPVRDSWITEEMEAIRRNFLPNDIGQILKDNKFDGVVAVQADQSVKETEFLVELSGFYKLIKAVVGWVDLRSDTVEEQLERFKQHTIIKGFRHIIEGESDPDFLHRDEFLRGIAALTKHQYTYDLLIRPRHYASTLKCVSANPDQAFMLDHIAKPPIKSQEFDEWAQFIADLSGYSNVHCKISGLATEADWKHWTLDHFTQYIEHVIACFGKDRVMFGSDWPVCLLAGTYEDSINIVADKLQDFSEAELKGFWGDNAVKFYSIT
>NZ_CP030848.1|WP_149526580.1|3096759_3099771_+|protein-translocase-subunit-SecDF
MQSKGLIQFLVVVVTLACLYSLSFTFVTRKVEKDAAAYAQGDMAKEKAYLDSMAGEEVYNLGIAKFTYREAKANELALGLDLKGGMNVTMEIALNELIANLANNPKDPNFNKALETAVTKAKTTNTSLIDLFINEYKATGAGTPIASFFATKDNSSVIKASSSEGELKSFLNAEADNAIQNSYKVLRTRIDKFGVASPNIQIQQGTNRILIELPGVSDQERVRKLLQGSAKLEFYETYNNLQIYPLLENINGTLATSLKGEKPATAADTTVKAAADTTAKEENLLANLNANKADSAKDTTNAVANATALANNPLFAILSPSFYQAPNGQTQLIPGSTVGYANLKDTAKVNQYLARPEIKSIIPADLKLLWAVKPETNTPNILALHAIKTTGADHKAVMTGDVITDARPGSDPQTNKPIVSMDMNADGARQWRRVTAQAAQNKDAIAIVLDNVVYSAPTVNDEIPGGSSTISGNFTFEDTKDLSNVLKAGRLPTTAKIVEEAVVGPSLGQVAIDSGVNSSVIGIIVVMMFMIAYYNRAGIAANIAVLFNVFFLMGVLASLNAVLTLPGIAGIVLTMGTAVDANVLIYERMREELSLGKSMRQVVSDGYKHALPSILDSQITTFLVGVILFFTGSGPIQGFATTLMIGIITSLFTAIFITRLIFEYMLSKEMKITVSFPWSNHTMKNANYKFIEKRKLFYGISLVAVVICFAAILTKGFSYGVDFQGGRTYTVKFDQPVAAEAVRESLDNVFGTTTEVKTFGSENQLRVTTSYHIQETSDEADQEVLGKLNEGLSKVQGKYEILSQQKVGPTIASDIRDRAIYAAVLSIIVIAAYILIRFRRWQYSAGAAIATIHDAIILLGLFSILDGLVPFSLDIDQHFVAAILTVLGYSVNDTVVVFDRLREYLGKPNAHHEKMDTTINKAINSTLSRTVITSLTVIFVLAVLFVFGGEVIRGFSFAILIGIVVATYSSIFLAAPAIYDLSAGKHLADSAKPEEKKQAKVIA
>NZ_CP030848.1|WP_149526581.1|3100311_3100938_+|redoxin-domain-containing-protein
MKTKFLIPILAISLSTVACNNNTSSNAEQTTDEHAGHDHSAAGHEGHNHAQTTTPNQAPPIEVPAVKAPVVSIPDFNFYKVKSGIAFSKADIPAGKNTVFVLFDPSCGHCQHETSALAKNYEKIKNINVYYVSMNDPALMASFFTSFGKELEGKPNVEMLYDRNQDFIQKFHVPSKFPANYVYGADGALKTYWEGEKSIEDVIAAFTK
>NZ_CP030848.1|WP_149526582.1|3100934_3101936_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MMKIAINGFGRIGRHTLRNLLNRKLSDIEVVAINDLADTKTLAHLFKYDSVHGPLYREVKHDDQHLYVDGKTIHVYNAKSPEDLPWAELGIDVVVESTGHFVKKELAEKHIQAGAKQVIISAPSPDKEVPTVVLGINDQDFDWSTPVFSNASCTTNNVAPLIKILDDNWQIQDGYITTVHSMTGDQNLHDAPHRDLRRSRAASASIIPTTTGAAKAITNVFKHLEGKLGGAGIRVPVLNGSLTDFTCTLAKETTVEEINQKFKEAADNGLKNVLYYTEDPIVSVDIINNPYSCVFDSQLTSIVGGLVKVVGWYDNEFGYSNRLVDLLEMVAKK
>NZ_CP030848.1|WP_149526583.1|3101932_3102367_+|GNAT-family-N-acetyltransferase
MIRFISLQDTLALRSLVLRNGLPEQECINPQDLLPETFHLGYFNEENEIVCVLTCQKENHPKLPHEAYRLRGMATHPDARRKGYAKELLLAAIDHLKEQLHIPYFWFNAREIAYPFYESVGFEYMSDEFDIPGIGPHKEMFKLL
>NZ_CP030848.1|WP_149526584.1|3102374_3103148_-|TIGR02757-family-protein
MDLSLKEFLDKKVEAFNTPDFIPADPISIPHRFTLKQDIEIMGFFASILAWGQRKTIINKCVELGERMDNAPFDFIINHQDEDLKQLLGFKHRTFNDTDLLYFVSFFKQHYQRYSSLEDAFLQEPFVAGVNRVEQALNSFRSYFFSLPDYPTRTRKHISSPLQKSSCKRLNMFLRWMVRKDNAGVDFGIWNRLRPSDLICPCDVHVERVARKFNLIQSDRVNWKTAVELTENLRELDPLDPVKYDFALFGIGVVGEM
>NZ_CP030848.1|WP_149526585.1|3103190_3104189_-|GTPase-ObgE
MAQGSNFVDYVKVCCRSGHGGAGSAHLHRDKFTAKGGPDGGDGGRGGHIILKGSTQHWTLLHLKFRKHIIAESGEPGGSALRSGATGKDEILEVPLGTVAKNAETGEVLFEITEDGETKILTAGGRGGLGNWHFKSSTQQTPRFAQPGMPGKEEWVILELKVLADVGLVGFPNAGKSTLLSVVSAAKPEIADYPFTTLVPNLGIVSYRDNKSFVMADIPGIIEGASEGKGLGHRFLRHIERNSVLLFMVPADTDRTIEEEYDILLNELTAYNPELLDKPKLLAITKSDMLDEELEEEMELQVPKGIPHVFISSVTGKNIQQLKDLIWKEINK
>NZ_CP030848.1|WP_149526586.1|3104206_3104776_-|adenylate-kinase
MLNLVLFGPPGAGKGTQSAKLIEKYGLHHISTGDIFRGHIKNQTDLGKQVSQIIADGNLVPDSITIAMLEEEIKQNPEAKGFIFDGFPRTVAQAEALDAFLESNNTSISGVVALDVDETELTQRIAKRQEISGRADDAADKLKKRIEEYFGKTIHVLPYYEGQGKLTKVNGIGDIEEIFNNLTTVIDRY
>NZ_CP030848.1|WP_149526587.1|3105478_3106306_+|alpha/beta-fold-hydrolase
MAERIIKSNKIRIGDLSIAYHIKKATETPEKTIIFLHGFPFNKNMWRDQLESLEDNVTGIAVDIRGHGNSTKGHGFFSIDVFAKDLGVLMRKLEIEDAILCGISMGGYIALRAYQLFPEKISGLILCDTHSKADDNAGKQKRFDAVQAVLQHGRRPYAIGFVGNVFSARSVEDKPEAVELIKSSIRRNSISSICATLLALAARTDTTDVLSEIKVPTLIIRGKEDKITPAELMEELHKKIKGSTYIEFEHCGHLPNLEDTEKFNLHMNTFIQEKV
>NZ_CP030848.1|WP_149526588.1|3106504_3107335_-|patatin
MNILKSKRKVSLVLGSGGARGLVQIGVIRSLEEKGYEIDEVVGCSIGALIGAAYVEGRLQQLEDWMLSINRSMIFKLLDFTNPKFGLLKGERVFESLKDIFPDKNIEDMDIPFRAIATDIKNEREVVFERGSVYKAIRASIAIPAVFTSVLSDDISLVDGGVVNPLPINFVKRKRRNIVVAVNLDGKPNPRYGPVAFDKPVNSIGMLQEAYFVMRRKLAALSVELYKPDYVINIPHNIAGLWDYDKATQLIEHGKMLTNKVVPDAAYRKKVVMEEK
>NZ_CP030848.1|WP_149526589.1|3107459_3108065_+|TetR-family-transcriptional-regulator
MGLSERKLRHQQEVKNQIIASSREIVNMEGWAALSIRKIADAIEYSVPVVYKHFESKEAITAFFVAEGFAALKKEMEACVVPTDPIEKRVQQLAEGYWLFASKNPKDYELMFGVGLPTCEMHQQVPAIAELANYLRQFIDELIESSGKKDLNTCVKYRSFWSILHGVVAIELLTINRWDSVCPSEVLADSIQAFTQSIQKN

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Crispr_ID: NZ_CP030848_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_16

3192414-3192505

Orphan

Consensus_repeat	Method
ATTTAGTATTAAGACCTAGAAAGAAGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_16

>merge|NZ_CP030848|16|3192414-3192505|CRISPRCasFinder
ATTTAGTATTAAGACCTAGAAAGAAGGTATTAACGCTAAGTTAGGCTAGTATTTAATAGTTCGAATTTATTATTAAGACCTAGAAAGAAGGT

>NZ_CP030848|16|16|3192414-3192505|CRISPRCasFinder
ATTTAGTATTAAGACCTAGAAAGAAGGT	ATTAACGCTAAGTTAGGCTAGTATTTAATAGTTCGA
ATTTATTATTAAGACCTAGAAAGAAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526655.1\|3190983_3192393_+\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|293736
NZ_CP030848.1\|WP_149526658.1\|3194224_3194683_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NZ_CP030848.1\|WP_149526651.1\|3186952_3187486_+\|lipocalin	unknown	unknown	gnl\|CDD\|381213
NZ_CP030848.1\|WP_149526652.1\|3187597_3188503_-\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526660.1\|3195164_3196409_+\|DUF695-domain-containing-protein	unknown	unknown	gnl\|CDD\|368292
NZ_CP030848.1\|WP_149526647.1\|3180249_3181662_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
NZ_CP030848.1\|WP_149526653.1\|3189089_3189398_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526657.1\|3193384_3194074_-\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NZ_CP030848.1\|WP_149526662.1\|3196870_3198082_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP030848.1\|WP_149526654.1\|3189509_3190853_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP030848.1\|WP_149526661.1\|3196423_3196861_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP030848.1\|WP_149526665.1\|3199297_3200182_+\|DUF3347-domain-containing-protein	unknown	unknown	gnl\|CDD\|378730
NZ_CP030848.1\|WP_149526664.1\|3198830_3199220_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526646.1\|3179554_3180187_+\|DUF45-domain-containing-protein	unknown	unknown	gnl\|CDD\|307807
NZ_CP030848.1\|WP_149526659.1\|3194694_3195099_+\|DUF5606-domain-containg-protein	unknown	unknown	gnl\|CDD\|375774
NZ_CP030848.1\|WP_149526649.1\|3185614_3186406_-\|S1/P1-nuclease	unknown	unknown	gnl\|CDD\|211382
NZ_CP030848.1\|WP_149526648.1\|3181661_3185411_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP030848.1\|WP_149526656.1\|3192587_3193301_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NZ_CP030848.1\|WP_149526663.1\|3198171_3198780_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|368581
NZ_CP030848.1\|WP_149526650.1\|3186413_3186875_-\|DUF4268-domain-containing-protein	unknown	unknown	gnl\|CDD\|379461

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526655.1\|3190983_3192393_+\|alkaline-phosphatase	gnl\|CDD\|293736	cd16012, ALP, Alkaline Phosphatase. Alkaline phosphatases are non-specific membrane-bound phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH. Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymatic activity. Mammalian alkaline phosphatase is divided into four isozymes depending upon the site of tissue expression. They are Intestinal ALP, Placental ALP, Germ cell ALP and tissue nonspecific alkaline phosphatase or liver/bone/kidney (L/B/K) ALP.	2.79967e-107
NZ_CP030848.1\|WP_149526658.1\|3194224_3194683_+\|peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	1.84097e-57
NZ_CP030848.1\|WP_149526651.1\|3186952_3187486_+\|lipocalin	gnl\|CDD\|381213	cd19438, lipocalin_Blc-like, bacterial lipocalin Blc, Arabidopsis thaliana temperature-induced lipocalin-1, and similar proteins. Escherichia coli bacterial lipocalin (Blc, also known as YjeL) is an outer membrane lipoprotein involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Blc has a binding preference for lysophospholipids. This group includes eukaryotic lipocalins such as Arabidopsis thaliana temperature-induced lipocalin-1 (TIL) which is involved in thermotolerance, oxidative, salt, drought and high light stress tolerance, and is needed for seed longevity by ensuring polyunsaturated lipids integrity. This group belongs to the lipocalin/cytosolic fatty-acid binding protein family which have a large beta-barrel ligand-binding cavity. Lipocalins are mainly low molecular weight extracellular proteins that bind principally small hydrophobic ligands, and form covalent or non-covalent complexes with soluble macromolecules, as well as membrane bound-receptors. They participate in processes such as ligand transport, modulation of cell growth and metabolism, regulation of immune response, smell reception, tissue development and animal behavior. Cytosolic fatty-acid binding proteins, also bind hydrophobic ligands in a non-covalent, reversible manner, and have been implicated in intracellular uptake, transport and storage of hydrophobic ligands, regulation of lipid metabolism and sequestration of excess toxic fatty acids, as well as in signaling, gene expression, inflammation, cell growth and proliferation, and cancer development.	8.21955e-66
NZ_CP030848.1\|WP_149526661.1\|3196423_3196861_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.93347e-12
NZ_CP030848.1\|WP_149526660.1\|3195164_3196409_+\|DUF695-domain-containing-protein	gnl\|CDD\|368292	pfam05117, DUF695, Family of unknown function (DUF695). Family of uncharacterized bacterial proteins.	5.7945e-15
NZ_CP030848.1\|WP_149526647.1\|3180249_3181662_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	7.34304e-25
NZ_CP030848.1\|WP_149526662.1\|3196870_3198082_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.38836e-20
NZ_CP030848.1\|WP_149526657.1\|3193384_3194074_-\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	3.71721e-79
NZ_CP030848.1\|WP_149526654.1\|3189509_3190853_-\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	8.4066e-28
NZ_CP030848.1\|WP_149526665.1\|3199297_3200182_+\|DUF3347-domain-containing-protein	gnl\|CDD\|378730	pfam11827, DUF3347, Protein of unknown function (DUF3347). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 169 to 570 amino acids in length.	4.00871e-55
NZ_CP030848.1\|WP_149526646.1\|3179554_3180187_+\|DUF45-domain-containing-protein	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	0.000116865
NZ_CP030848.1\|WP_149526659.1\|3194694_3195099_+\|DUF5606-domain-containg-protein	gnl\|CDD\|375774	pfam18347, DUF5606, Domain of unknown function (DUF5606). This is a domain of unknown function found at the N-terminal region of bacterial proteins.	1.35759e-12
NZ_CP030848.1\|WP_149526649.1\|3185614_3186406_-\|S1/P1-nuclease	gnl\|CDD\|211382	cd11010, S1-P1_nuclease, S1/P1 nucleases and related enzymes. This family summarizes both S1 and P1 nucleases (EC:3.1.30.1) which cleave RNA and single stranded DNA with no base specificity. S1 nuclease is more active on DNA than RNA. Its reaction products are oligonucleotides or single nucleotides with 5' phosphoryl groups. Although its primary substrate is single-stranded, it may also introduce single-stranded breaks in double-stranded DNA or RNA, or DNA-RNA hybrids. It is used as a reagent in nuclease protection assays and in removing single stranded tails from DNA molecules to create blunt ended molecules and opening hairpin loops generated during synthesis of double stranded cDNA. P1 nuclease cleaves its substrate at every position yielding nucleoside 5' monophosphates, and it does not recognize or act on double-stranded DNA. It is useful at removing single stranded strands hanging off the end of double stranded DNA and at completely cleaving melted DNA for simple DNA composition analysis.	2.0363e-71
NZ_CP030848.1\|WP_149526648.1\|3181661_3185411_-\|hypothetical-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	1.1902e-18
NZ_CP030848.1\|WP_149526656.1\|3192587_3193301_-\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	4.8146e-71
NZ_CP030848.1\|WP_149526663.1\|3198171_3198780_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|368581	pfam05724, TPMT, Thiopurine S-methyltransferase (TPMT). This family consists of thiopurine S-methyltransferase proteins from both eukaryotes and prokaryotes. Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyzes S-methylation of aromatic and heterocyclic sulfhydryl compounds, including anticancer and immunosuppressive thiopurines.	9.98767e-30
NZ_CP030848.1\|WP_149526650.1\|3186413_3186875_-\|DUF4268-domain-containing-protein	gnl\|CDD\|379461	pfam14088, DUF4268, Domain of unknown function (DUF4268). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 151 and 387 amino acids in length.	1.36556e-37

>NZ_CP030848.1|WP_149526655.1|3190983_3192393_+|alkaline-phosphatase
MIKRSISFFFAFVLCVGLSFGQKQPKYIFYLIGDGMGLNQVQAAEVFLASQQNKNSTVPMVFSTFPYATHATSHSLSHGVTDSGAGGTALAVGYKTKNGVIGMDSAGVKAYESIAYKAKKKGMKVGITTSVSIDHATPASFFANQKDRDMYYEIGQDIIKSNFDFFAGAGFLKPETNAKGEKVAPLIPQLEKAGYTMLYGMNDFNKVKSGKNKLILMNNQGTSPVSLKFAIDQEANDMNLANITEAAIKTLSQGNQGFFLMVEGGKIDWACHANDGAAAIQEVLDFNKAVQKAYDFYQKHPEETLIIVTADHETGGMGVGNGGSTLRINNIKNQKISQEALSTKINELREKNNSASWEQVKALLSEQTGLWNNVKVSEKEEKEIFAAYEKSFVNHQNETAKSLYANNDKIASLAINALNKVSSISWASGSHSAAYIPVYAIGVGAENFSHKMDNVDIPRTLGKVAGWEF
>NZ_CP030848.1|WP_149526654.1|3189509_3190853_-|OmpA-family-protein
MENSLLTTARSYFNDQVFDNLAAKHGESSDNVRKGLDAVIPSLFLGLQSKSPSEQSGIFDVLKQYFSQINFSDLGSVWNRVDNDPADAEKGSHLISSIFGGGLDQVIATISGFLHTNGSSVMQLFKTALPGVIGALTKNGTDWDTSRISGLLDNNKSDFLAALPSGLNLGVLGSSLLSQPGVVEGRPVTPPSEREPIVDPVRDVVVDDPIVPPVTRMENRAEDRPVAHIREEERKKGGGLWWLLIPLLLLLLWFLFGKGCSRENETATTDTIPSTVAPVDTIVDTVTTAPVRESIMVTLPDNSTLNAYKGGIEDQLVAFLNSDYKQFSDDQLKDRWFDFDNLNFETGTSTITADSQTQLQNLAAILKVYPDVKVKIGGYTDKTGDEAFNLKLSGERADAVKAELDKMGVGDRVVDTEGYGSSLAKYEANAPESDRIKDRRVSISVRK
>NZ_CP030848.1|WP_149526653.1|3189089_3189398_-|hypothetical-protein
MLTATQMNMLQGDFEKFLSHLRSQKKSLSFELFGDYAGSVLNFYLGSSLINPAEKLEAAQVLTGLFNAGLKNIISPQDLMEIAESIAQDTTLEYGVIQAIFD
>NZ_CP030848.1|WP_149526652.1|3187597_3188503_-|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSMHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVVEDFAPEECSREFSLLDSMPIITCSGTRRAKVALEIMDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSKVRQPIESFFNWINEKTQIQNASKVRSTKGRLVHVFGNLTPIKPNWERF
>NZ_CP030848.1|WP_149526651.1|3186952_3187486_+|lipocalin
MDKKKSLIALSAVALGTVAYNLLRPVKSKVDVIEPFDLQKYLGRWYEIARFDFRWEKNLKNVTADYSLNEDGSVLVNNQGINITTGKHKQSIGKAKFVDEENRGALKVSFFGPFYAGYNIVKLDENYQDALIFGDNLDYIWFLSRNKTMSKERKEAYLNYAQAHGYDTSKLVWTIQE
>NZ_CP030848.1|WP_149526650.1|3186413_3186875_-|DUF4268-domain-containing-protein
MYSREEAKRIRESFWTSFGQYMTPIAGADGLKVNWINYKTGIKHLYFRMDADNKKAHIAIEMAHPDAGIRALLFEQFRQYQAVLEAEFGEEWIWDEHSFDDYGKETARIFMELPKVSVFQQEDWPALISFFKPRIIALDSFWSDAQYGFELFK
>NZ_CP030848.1|WP_149526649.1|3185614_3186406_-|S1/P1-nuclease
MKTVAKIVLFFTLLTSSQQLFAWGMTGHRVISEIAEKHLTRKAKRNIEALIGKQKIAYWSNWADFIKSSPDPLLNSTGSWHFLNTAGNLSFEEFNTALQNSPEQNLYKAYAKVRAQVNDKNLSIAQRREALYYVIHLLGDAHQPMHVSRAEDLGGNKINVTFFGRQGNIHRVWDSDLVDNEKYSFMEYAAVLDYDKSFFKKYTNSGFEQWLYESHQLANVIYDDVAKQNKLSYDYIFRFKYPMEECLLKAGLRLAKELNDIFG
>NZ_CP030848.1|WP_149526648.1|3181661_3185411_-|hypothetical-protein
MVFVNHIERKPIKTEIFMDMTLCKPTYARREVGRAHERFFLNLSMILFLFCLCNVDVWAQDRVQLFGVVRDAESKQPIPKATVTVLDSRFVMETNELGEYAFECINQDKIEITFSCVGYAPLVYSLRQLKRRNDIQLKKQVRRIEEAIVRHRNPKNVLLDIEQRRHLNLGQMLEGTVPGLIFRPSTTTEQEVIFSTPTLNISGSMNLREMYDQMKRTMPEAMVLYPTFQDFQRDFDQKRSTLMRAAGSNIINQTKLSSMGLVPEFRGGSALPGDTKGMLVLVDGFPEAEFPLNMPMANIESVEVIRDPEEGIKYDPEGVNGVVLIKTMRGSVGKPLEIHYTQNFFISDLEDISNKALERISSRDLLDLYRDRFDLDITPMTNLHLPYIGVNPAYLLLNHHRHDKISASEFEHRWDSLGNLDNQQQIRQTQQRVGMQNYNLRLAGRKDEVRYNLSLMYSDNKSSSPGDYMRNFDLNSNNTFSFFKNKVEGNLYVRYRRGENKTVPRLSMSLEPYQMLFDEQGNYVYDYNDTYRYDLNQQFMSLGAFDVGRNHVEDQRLNYSLGRNRMLSASGKVQVNFNPSLSWINTMLYQRTNNRTEQFTHEHSTDARRHFNMYSIPVKDKGINYWAPVGNYNQRGGSLETTIDFRSGFDFNKTVSDIHQFKAGLSGWVSMSDAKMNPVEIFYGVDARGRGGDTIWMEPTAARNIYGEPVETGSLINIPQPQNQRNRNLRIGGNFGYSYRETFQTKFTYNGVYIPNYGVKPNYAMFHDASLLVDWDLHQRFIPENRIINELLKGTKIGGLRSPRLPAQHQASRNLETNWDYYSISLTNYFDPNMSNINLNYAKTSLYLGLFNDLMKFQASAYINNQDRTLWSGDFNYNLKQHLLTKLDFLSTLSLVYSLQNFDQYQSLLIQFELNQLNRHSVVQPNFLVMEFLPPAILNHEPSIQLGFLSDRFLVDIRKYDRLTTGIMVDMYNLPDFATGLQSRYVKNTIRTKGLEFASTLKLFERSRFRWNVNVLASFNDIVNVEVPEQEYIANYAYLVTPRNNYSQNALWSYRWGGLNDEGEPTILNDKGTRLDAAEESALVFSGVTIAPNTGSVNQFIDVGDFFFQTRINWQSGGVMRKYIPAPSSSIDHHSDLVYRWRKPGDENLTDIPKLANYNVGRELITQNSTNSILSSDFIRLEEIQVGYHFPRHITAPMRMSRLSVSVQMNNIWFWARNPYGYDPRSVANNGILSPQMPRQYSFSINASF
>NZ_CP030848.1|WP_149526647.1|3180249_3181662_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTLQYNILIYAFVGCFLSSCSKFLDVNPNTGEQISVRNFVDFEEVLNSRDFASHNMIIAEFLTDNIYFHPDSVARMPSDYSLRNAYLWNESIWNNNDTDELYRALYKNIAQANLVINYLDFALDGTAEGKRRLIAKAKIHRAYANFMLVNLYGPQFNAASAESDLAVPLITILDANQLPPHATVKQLYDLIERDLQDAMATAELPDKGNDVLHPGKVCAYALSAKVHLQKGEYEQAMDYANKALAINSFLIDYNPFLMEYESYVFLLFQMEGYQEVIFAKAGQELNFFQTTGLNIYMPEDLLSIYTENDLRLFAHYGQNYDTWEYIYPIVAAPDGSSSAVRFNNAITVPEMMLIAAECNARDGKVEEAMALINKLRFKRMLEDTHEDLEAASPEEALKHVLDERRRELSFKGGIRLMDIKRLANDAVNRTVLNRFDGEGNIMKSIEPNSRQLIIPLTPRALVFNPNLRD
>NZ_CP030848.1|WP_149526646.1|3179554_3180187_+|DUF45-domain-containing-protein
MLIKVDEKDYNLLTTEKREIRIANLQEDIPTVYAHAQNSLDEVATYIRQFQQGSAFQVAPESMLEFFRIDLFGKKYPVKIIRNEEFQPYIKADLVYCSAKANTDIQQEKFAENLREQLFQQYVLQRISHWEEQLNVLSNDINFRVLKASPYKTNAETANITFNKQIKDLSLRTIDYFVFSAILPLLHEDDELTLINQYFPDTERLLNQLR
>NZ_CP030848.1|WP_149526656.1|3192587_3193301_-|pirin-family-protein
MAKYIYHEADSRGDANHGWLHSRHTFSFAGYMDAERMNFGVLRVLNDDYVSGGMGFGRHPHSNMEIISIPLEGELAHNDSMGNGSVIKPGDIQVMSAGTGIEHSEYNHSEVDPVKFLQIWVIPNKQNVEPRYDQQAIDKEKAHNNFLQILSPNADDEGVWIHQNAWFHLAEFEAGYTREYVLKDPSNGLYVFVLKGDIEVGKQLMHTRDGLGIIGEKHVSIKASTPAEFLLMEVPVG
>NZ_CP030848.1|WP_149526657.1|3193384_3194074_-|DNA-repair-protein-RadC
MFQKMVIREWAEADRPREKLLERGRRAVTDAELLAIVIGSGSRTETAVELCKRVLAGVNHNLLQLSKLEVHDLCEYKGIGEAKAISIIAALELGRRRQETKQTDIPILNSSKLVYEFFRSQLQDLPHEEFWTIYLNTACKVVDTQLIGRGGNDFTPVDIRTIFRFALLNKCHSIILAHNHPSGTLKASDTDIKITQKIVRAAELIDIRVHDHLIFTDCAYLSFRDEGLL
>NZ_CP030848.1|WP_149526658.1|3194224_3194683_+|peptidylprolyl-isomerase
MSKAIIKTEKGDMTVQFYTEDAPNTVANFIKLAKSGYYDGLTFHRVINDFVIQGGCPNTREGATGMPGTGGPGYKIDCELDGNNQYHDRGVLSMAHAGRNTGGSQFFICHSRNNTAHLDRNHTCFGKVIENVDVVDDIRQGDRILGIEVIED
>NZ_CP030848.1|WP_149526659.1|3194694_3195099_+|DUF5606-domain-containg-protein
MNLRGLVSVTGKPGLFKLIGQNKGGFILETLDKAKIKSVVNLSTTKMATLEDITIYGEDDEIRLIDVFEAIKANDGNTPDAKADGDTLRNFFREVAPGHDEQRVYSSDIKKVITWYHIIKELPLFEEEAPAPLA
>NZ_CP030848.1|WP_149526660.1|3195164_3196409_+|DUF695-domain-containing-protein
MAISNFHPQYCSQWKDESFKRKYALKFNYPPILIKLLSISTKRKVMSVFNKLFKSNSADDNNIETIADFWKWFERKADTFYNAIDEGADIENKFFSPLADQLYKLHERIFFLVGINKETNIAELTFTPDAIIRNIAFVEDLVREAPQIDKWQFVALKQASDVEGFGVKMFGRDFSSKNIQFYPVEHPEFPDEIDIIAVYDDYDEKDHDDIFNGVCIYLDNSLGELKSITMIDNMRVRGPGDDIPELIPIEKLDAYLIWREKEFVERYTDITHYSKEDHYGSYQGELENGMPIFAIVNHTLLNWEHKASHPWILVVMIHYDPNPETGLPNERIYKLMEDLEVELMDRLRDVDGYINVIRETGNGLREINFACREFRKPSRVMEEIAVKYAEHFRVEFDIYKDKYWRSFDKFNAEN
>NZ_CP030848.1|WP_149526661.1|3196423_3196861_+|GNAT-family-N-acetyltransferase
MTIRPYQANDLSEVLNLLSSNIPTYFAPEEYEDLKTYLAHEIEDYYVVEQDNHIVAAGGINYKEQDAYISWDFVDAHMHGSGIGKQLLQYRLDRIKTQGKVKRIIVRTSQFAYGFYEKNGFVIKEQHKDYWAPGFDMIFMVYQEN
>NZ_CP030848.1|WP_149526662.1|3196870_3198082_+|methyltransferase-domain-containing-protein
MEIDLSKYHQKKRIIDLVKANTLGCLAVFPIALVYIVPYILIWSDQFTKESIKQTLNSIGAGTAFLNGIGFFLVLIVGIVVHEAIHGLTWSIYAKGGHKAMKYGILKKMLTPYCHCREPLKLKHYIIGAAMPGLLMGVLPAIIAIAIGSPTLLMLAIIFTLVAIGDAMIINLVRKEDPESLVLDHPSEAGCYILTEKQELEDKSETFDTWNNIAEIYETKFMDMDIYNESYDALLKHLPNKQGRILDVGCGPGNSARYLLKFYPSLQIVGIDIAENMLEIARKHVPTGEFYLLDARAISILNGQFDAVIAGFCIPYLNASETEQFLDDASEKLNNKGLLYLSFVEGDPAAPEVKSNPLGSVKFYFHRERELQKELKTRGFKLIKSTIIPYDAEDNHTVMLFQK
>NZ_CP030848.1|WP_149526663.1|3198171_3198780_+|methyltransferase-domain-containing-protein
MEGNNELRDPQSAQTFWNTRWETKQTGWDIGYASPALTHYVDGLTNKDIAILIPGCGNAYEASYLVEKGFSNITLIDIAPIAVANAQEKFKDNPEVKVILGNFFELDESYDLVLEQTFFCAIDPSLRPQYIQKMASLLNPAGRLVGLLFNIDFEKDGPPFGGHIAEYHPAFAAYFDIHKMEPCYNSIQPRQGSELFINLIKK
>NZ_CP030848.1|WP_149526664.1|3198830_3199220_+|hypothetical-protein
MKSLFLICLLSFAMFIPSLGQACEIPHEKEETQHCEHQSSEQKDAEEHACCHKDAEQSKENSSSTERPMGCAGKGICCCATPMIGHLQLGIFLFEFEIPSYTVNIQNTEVQQFVVSNGFSSIFIPPKIA
>NZ_CP030848.1|WP_149526665.1|3199297_3200182_+|DUF3347-domain-containing-protein
MKNLKAFIASIIIISSLTVHAQIKNATTSTVEIKGNCAMCKKTIEAAAYEPKVSKAEWDEDTQQAVLTFNPDKTSEEAILKKIAQAGYDNQSFRAPDDVYAKLHECCLYERDHTVAKAEHNEHQGMDHSQHKPSAKEHANIDHSQHNGDATANTQLAPVFKNYLAVKNALVATDAKAAATAAKALTASIGQVEMGKLAHEEHEVWMKVMKGIQTEAASIEKSTDINRQRQSFMALSNHLYSLAKASQGSTALYWQFCPMANNNKGAYWLSAEDAIKNPYFGSKMMNCGEVKEKI

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Crispr_ID: NZ_CP030848_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_17

3372679-3372791

Orphan

Consensus_repeat	Method
ATCCTTCCTTTCCTGGTTCAAAGACAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_17

>merge|NZ_CP030848|17|3372679-3372791|CRISPRCasFinder
ATCCTTCCTTTCCTGGTTCAAAGACAGTATTTAGTAGTTAGTACTTAGTAGTTAGACCCATGACGTCCGATCCTGCCAATCCTTAAATCCTTCCTTTCCTGGTTCAAAGACAG

>NZ_CP030848|17|17|3372679-3372791|CRISPRCasFinder
ATCCTTCCTTTCCTGGTTCAAAGACAG	TATTTAGTAGTTAGTACTTAGTAGTTAGACCCATGACGTCCGATCCTGCCAATCCTTAA
ATCCTTCCTTTCCTGGTTCAAAGACAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526776.1\|3361762_3362236_-\|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	unknown	unknown	gnl\|CDD\|376840
NZ_CP030848.1\|WP_149526777.1\|3362412_3363051_-\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NZ_CP030848.1\|WP_149526783.1\|3370884_3371655_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187604
NZ_CP030848.1\|WP_149527741.1\|3375777_3376662_+\|NAD-kinase	unknown	unknown	gnl\|CDD\|179352
NZ_CP030848.1\|WP_149526789.1\|3377003_3377741_+\|isoprenyl-transferase	unknown	unknown	gnl\|CDD\|184840
NZ_CP030848.1\|WP_149526780.1\|3365332_3367615_-\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273429
NZ_CP030848.1\|WP_149526791.1\|3380496_3381030_+\|OmpH-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|377167
NZ_CP030848.1\|WP_149526794.1\|3383715_3385008_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|223325
NZ_CP030848.1\|WP_149526792.1\|3381127_3381685_+\|OmpH-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|377167
NZ_CP030848.1\|WP_149526787.1\|3374051_3374885_-\|glycerol-acyltransferase	unknown	unknown	gnl\|CDD\|153248
NZ_CP030848.1\|WP_149526778.1\|3363148_3364474_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP030848.1\|WP_149526781.1\|3368125_3369721_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NZ_CP030848.1\|WP_149526785.1\|3372121_3372571_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225064
NZ_CP030848.1\|WP_149526779.1\|3364552_3365275_-\|DUF4290-domain-containing-protein	unknown	unknown	gnl\|CDD\|379482
NZ_CP030848.1\|WP_149526784.1\|3371656_3372106_+\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP030848.1\|WP_149526782.1\|3370116_3370854_+\|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	unknown	unknown	gnl\|CDD\|234689
NZ_CP030848.1\|WP_149526788.1\|3375057_3375720_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341419
NZ_CP030848.1\|WP_149526786.1\|3373082_3374048_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379189
NZ_CP030848.1\|WP_149526793.1\|3381767_3383459_-\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP030848.1\|WP_149526790.1\|3377861_3380435_+\|outer-membrane-protein-assembly-factor-BamA	unknown	unknown	gnl\|CDD\|274514

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526776.1\|3361762_3362236_-\|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	gnl\|CDD\|376840	pfam02590, SPOUT_MTase, Predicted SPOUT methyltransferase. This family of proteins are predicted to be SPOUT methyltransferases.	1.01233e-85
NZ_CP030848.1\|WP_149526777.1\|3362412_3363051_-\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	7.06469e-31
NZ_CP030848.1\|WP_149526783.1\|3370884_3371655_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.7881e-130
NZ_CP030848.1\|WP_149527741.1\|3375777_3376662_+\|NAD-kinase	gnl\|CDD\|179352	PRK01911, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	2.14901e-144
NZ_CP030848.1\|WP_149526789.1\|3377003_3377741_+\|isoprenyl-transferase	gnl\|CDD\|184840	PRK14830, PRK14830, undecaprenyl pyrophosphate synthase; Provisional.	5.80257e-136
NZ_CP030848.1\|WP_149526780.1\|3365332_3367615_-\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP030848.1\|WP_149526791.1\|3380496_3381030_+\|OmpH-family-outer-membrane-protein	gnl\|CDD\|377167	pfam03938, OmpH, Outer membrane protein (OmpH-like). This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.	2.74704e-30
NZ_CP030848.1\|WP_149526794.1\|3383715_3385008_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	4.51353e-21
NZ_CP030848.1\|WP_149526792.1\|3381127_3381685_+\|OmpH-family-outer-membrane-protein	gnl\|CDD\|377167	pfam03938, OmpH, Outer membrane protein (OmpH-like). This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.	1.17972e-24
NZ_CP030848.1\|WP_149526787.1\|3374051_3374885_-\|glycerol-acyltransferase	gnl\|CDD\|153248	cd07986, LPLAT_ACT14924-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Pectobacterium carotovorum subsp. carotovorum PC1 locus ACT14924 putative acyltransferase, and similar proteins.	2.18943e-55
NZ_CP030848.1\|WP_149526778.1\|3363148_3364474_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP030848.1\|WP_149526781.1\|3368125_3369721_-\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP030848.1\|WP_149526785.1\|3372121_3372571_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	3.53753e-60
NZ_CP030848.1\|WP_149526779.1\|3364552_3365275_-\|DUF4290-domain-containing-protein	gnl\|CDD\|379482	pfam14123, DUF4290, Domain of unknown function (DUF4290). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 200 and 221 amino acids in length. There are two conserved sequence motifs: EYGR and KLWD.	6.16011e-100
NZ_CP030848.1\|WP_149526784.1\|3371656_3372106_+\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.71914e-45
NZ_CP030848.1\|WP_149526782.1\|3370116_3370854_+\|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	gnl\|CDD\|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	6.19793e-103
NZ_CP030848.1\|WP_149526788.1\|3375057_3375720_+\|CBS-domain-containing-protein	gnl\|CDD\|341419	cd17783, CBS_pair_bac, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	7.15537e-28
NZ_CP030848.1\|WP_149526786.1\|3373082_3374048_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379189	pfam13444, Acetyltransf_5, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions.	1.53645e-11
NZ_CP030848.1\|WP_149526793.1\|3381767_3383459_-\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	7.3436e-63
NZ_CP030848.1\|WP_149526790.1\|3377861_3380435_+\|outer-membrane-protein-assembly-factor-BamA	gnl\|CDD\|274514	TIGR03303, OM_YaeT, outer membrane protein assembly complex, YaeT protein. Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking].	3.05301e-95

>NZ_CP030848.1|WP_149526785.1|3372121_3372571_+|GNAT-family-N-acetyltransferase
MNWVIKSFDDLSAKELYRILQVRIDVFMLEQNCLYPECDDKDLKSKHLFLMEQDQCAAYARLLPPDVSYPNCSSIGRVVVHPNFRKQQLGQQLMKEAIQYQKNAYPNHTIRISAQLYLQAFYENLGFVRESDVYLEDDIPHVEMAFASS
>NZ_CP030848.1|WP_149526784.1|3371656_3372106_+|GatB/YqeY-domain-containing-protein
MSLETQINQDIKAAMIAKDNAKLRGLRAIKAAILLAKTEKGGADEMTEETEIKVLQKLVKQRKESAEIYQQQNREDLYQIEVEEQEVIESYLPKQLDRAAIEEVIKSIIAETGAASIKDMGKVMGLANQKLAGQADGRTISEVVKSLLS
>NZ_CP030848.1|WP_149526783.1|3370884_3371655_+|SDR-family-NAD(P)-dependent-oxidoreductase
MRTVLITGASSGIGAACALELAKDTNYRLLLCARRVDRLEELTSKIKQINPSCEVHTFKLDVRNADEVETTLSNIPAEWKNIDVLINNAGLSQGLDPIQTGDIGDWDRMIDTNVKGLLYVTRNVVPMMEGSQQAHIINLGSIAGKEVYPNGNVYCATKHAVDALNKAMRIDLLPKGIKVTAINPGMVETEFSEVRFHGDADRAKAVYQGVTPLSGQDIAEIIVFALNRPAHVNINDLLVMPTVQATGTIINRSNSK
>NZ_CP030848.1|WP_149526782.1|3370116_3370854_+|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE
MSNDASTVKPYNPEGGKKEQVADMFNNISKTYDLLNRFMTMGIDTIWRKKAIKLLKPLQPQMILDVATGTGDFALESIRILNPKKIIGVDISQGMLDVAAEKAKKKGVESQFEVRLGDSESLPFEDNTFDAVTVAFGVRNFENLEQGLSDIRRVLKPGGKAIILELSNPTAFPIKQLFNFYFHKVVPAMGKVISKDNRAYEYLPESVAKFPDGQRFAAITDKVGFASCNVRPQTFGFCTIYECNK
>NZ_CP030848.1|WP_149526781.1|3368125_3369721_-|replicative-DNA-helicase
MSVENENSNNMSSQASRANFNKKRTSLNNLVSGLGKLPPQAVDLEEAVLGALMLEKNALSEVIDILKPDSFYKESHQKIFQAIYNLFQKTSPIDILTVVAELRQMGALEMVGGAYYITQLTDRVVSAANIEFHARIISQKYIQRELIKVSTEIINSSYDETSDIFDLLDHAEKSLFDIAQNNLRRDSRKMDDIMREAISSLELLRDRTDGLTGIPSGLTALDRMTSGWQPSDLVIIAARPAMGKTAFVLSVARNAAVDHSRPVAVFSLEMSSVQLVNRLIAGETEIEQEKLKKGNLADHEWQQLHSRIGRLTEAPLIIDDTPALNVFEFRAKCRRLKAQYDIQMVIVDYLQLMHGKSEGKGGGNREQEIGSISRALKSVAKELNIPVLALSQLSRAVESRPGNSKRPMLSDLRESGSIEQDADMVLFLYRPEYYGITEDEEGRPTAGVGEVIIAKHRNGETGIVPLKFVGKYVKFVDLEDDFAGMGGDSGSFSDLPSGFGSAMAPSNSFDNFGGGITMPSRMNDMPDDAPF
>NZ_CP030848.1|WP_149526780.1|3365332_3367615_-|UvrD-helicase-domain-containing-protein
MDFLAGLNPSQRAAVEQTEGPVMIVAGAGSGKTRVITYRVAHLIQKGVDPFNILVLTFTNKAAKEMRERIMKVVGSEAKNIWMGTFHSVFARILRVEAELIGYPRNFTIYDTDDTKSLLRSILKEMNLDDKLYNVNHVYGRISSAKNNLISPQEYNKNEAIKAEDISNGRPQMGEIYMTYAQRCYRAGAMDFDDLLFKTNVLLNKYPEVLHKYQHQFRYLMVDEYQDTNFSQYLIVKRLAAVNENICVVGDDAQSIYAFRGANIQNILNFQKDYPDVKVFKLEQNYRSTKMIVNAANSIIANNKNQLEKNVFSDNEEGEKIKVTRAFSDNEEGKIVAEGISQEKALKGLKYKDFSILYRTNAQSRSLEEALRKLGIPYKLYGGTSFYQRKEIKDLIAYFRLTFNPNDEEALKRVINYPRRGIGDTTVDRIMVVADQQQVRLWDVVANAQMFLDGRSAASVGNFGTMIQSFQALAKTNSAFDTAMHIAQHSGILKELYEDKSVEGLSRYENIQELLNGIKEFSEREDLEEKGLDIFMQDIALLTNDDNDKDPNADTVSLMTIHSSKGLEFPVVFIVGLEENLFPSQLSLNSRTELEEERRLFYVAVTRAEKKLFLSYATSRYRWGTLNNCEPSRFLDELNPACLDLDFKPRLNTGGGSDDFTSERVTWQRKESSGDVFSKPKPKVVKTTSILPKAHVPTAGFAPSDTSGLQVGMEVEHERFGFGKVINLEGNKPDIKATIFFKELGQKQLLLKFAKLRILE
>NZ_CP030848.1|WP_149526779.1|3364552_3365275_-|DUF4290-domain-containing-protein
MIFDYNSTRPKLILAEYGRNVQNMVDYICTLSDREERNRLAQVVIDMMGVLNPHLRDVSDFKHKLWDHLYIISDFKIDVDSPYPIPKKEEIHHKPQTLQYPNHPIRFKHYGHTVEEMIKKAKALPNEEARVKMTIGIANFMKMAYLTWNKDSVSDDQILEDLKTLSQGELALPADTVLTKLDFKTPPPGSRVKTGSDNRSNNNQGSHSKGKGSFQRNDNNKGRTFNNNNNNNKQNIKRKK
>NZ_CP030848.1|WP_149526778.1|3363148_3364474_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MNAFEIRGGKPLKGEIVPQGAKNEALQIISAVLLTAEKMTISNIPDIKDVNKLIDLLIALGVKVNRVNEDTYEFEASDINIDYFQSEEFKRKGGSLRGSIMIVGPLLARFGKAAIPKPGGDKIGRRRLDTHFLGFEKLGAKFVYDAEKHFFNVDATELKGTYILLDEASVTGTANIVMAAVLAKGTTTIYNAACEPYLQQLCKMLNRMGAKISGIGSNLLTIEGVETLGGTEHRMLPDMIEIGSFIGLAAMTGSEITIKNVCFNELGIIPTVFSRLGIKFELRGDDIFIPAQDSYEIDTFIDGSILTISDAPWPGFTPDLLSIVLVTAIQAKGNVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRATVIGLNKQQHLRGIEMTSPDIRAGVSLLIAALSAQGKSVIYNIEQIERGYQHIEERLKALGADIRRIDAQPVGH
>NZ_CP030848.1|WP_149526777.1|3362412_3363051_-|YceI-family-protein
MKKITLLSAIAGLVLASCAGNPEGKKAETTDSVVATTDSVAVAGEAYTVDTAESKVVWTGTKVSGKHTGTVDVKSGSINVENGTVTGGNFVLDMNTISATDLEGEYKEKLDGHLKADDFFAVATHPEASFVITEVKAGATAGDLVVSGNLTIKGISKNITFDAKVVEATDAAVKATANFNIARADWGVNYEGKSDDLISKEVNFDITLVAKK
>NZ_CP030848.1|WP_149526776.1|3361762_3362236_-|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH
MKISLICIGKTDDKYIEQGIEVYTKRLKHYCNFQIIVIPDIKNAKNLSEAQQKEKEAQLILKNISNQDYVMLLDERGKMYSSIEFSGFLEKQMLSSVSHIVLVIGGPYGFDQQVYDRANGKLSLSKMTFSHQMVRLFFVEQLYRAHTIMRGEPYHHE
>NZ_CP030848.1|WP_149526786.1|3373082_3374048_-|GNAT-family-N-acetyltransferase
MQEIIEPVDRALIKAELTKEAFVRYTNNGNNEVYLVNYHNSPNIMREIGRLREITFRGAGGGTGLPLDIDENDTCEHNYDQLIAWNPEDEEIIAGYRVIKCADAIDSNGEFHLSTAHYFEFSDKFVKDYLPYTLELGRSWVQPKYQPAIDNRKGIFSLDNLWDGLGAVVLMNPDVKYLFGKVTMYPQYNEEARDLLIYFMNYYFPDKDNLVKPVDELYLGYKTDISKHEGIFDGLDYKAGYKVLNTKVRELGENIPPLINTYMNLSPTMRVFGTARNNEFGEVEETGIMIILDDIYPAKKERHMSTFERDREFGSRKIEGK
>NZ_CP030848.1|WP_149526787.1|3374051_3374885_-|glycerol-acyltransferase
MGLLEKEKFIKIREVIHKKSPTLAKWIPKPLISYLERVIHEDEINYIMTTYHDDMGLDFVDSLLNELDVKVHLEGAENIPLEDSVIFASNHPLGGLDGVAFMQAIGKYRKDVKFLVNDILMNVRNLEPLFVPVNKLGGQSKSGIAAIENAYASDHALLVFPAGLVSRKINGKIVDLEWKKSFISKAKKYKKDIVPVYIDGRNSNFFYNLARFRNKVGLKANIEMLYLPDELFSQRGKDITIKIGKRIPYSQFDNSKNERQWAAEVKETVYAMSGGKK
>NZ_CP030848.1|WP_149526788.1|3375057_3375720_+|CBS-domain-containing-protein
MFIGEIITTLYTELRPSDTVDFALNKVNELHFHQLPVVKGKEYHGLLTEEDLLSVEDESDLISEVKITLPFIYLYDYQHIYDALQYLETYQYDILPVLNKQNQYVGCVTQTDLLRAINQTISNQEKGAIIVLEMEDRDNSLTHVAHIIESENTKILNTGVRPIENSTKVELTIKVNKNNISSVLASLWRHDYVVKASFNDGTDQNDIQERYNLLMNYLNI
>NZ_CP030848.1|WP_149527741.1|3375777_3376662_+|NAD-kinase
MSIAVYGREFNQSVIGYVVELFTYLRERNVQVYIYHDFHTFLKKLCKVDFKFKKFKTHKDLPKDISFMLSLGGDGTMLSAATLIGDSGIPIAGINFGRLGFLANISKNKIEEALDQILNNQYTVQPRALLQVESSDGTIKAGVSNALNDITVFRYDSSAMITVHAVLNGELLNSYWSDGLIIATPTGSTAYSLSCGGPIIMPGSGNFVITPVSPHNLNVRPIVVSEDMELRLNIESRTEKYIVSCDSKSYTLSTKTSLLITKAPYHVNLIRLKDDQYFGILREKLLWGIDVRNY
>NZ_CP030848.1|WP_149526789.1|3377003_3377741_+|isoprenyl-transferase
MDYKENIDKSNLPKHIAIIMDGNGRWAKEKGELRVFGHRNGVTAVREALEAAVEIGISYLTLYAFSTENWNRPQFEVDALMELLVDSLNKELPTFQKNNIRVNTIGRMADLPPHCQVTLQSTIDQTKDNTGCTLTLALSYGSRQEILDATKTIAQKVQSGELSLEDINEPTFSENLYTKAIPDPEMMIRTSGEQRISNYMLWQLAYTELFFLPIMWPEFSREHLFECIYLYQNRERRFGKTSEQL
>NZ_CP030848.1|WP_149526790.1|3377861_3380435_+|outer-membrane-protein-assembly-factor-BamA
MKHKIKLTLLLTIFLLNFAHAQIPGNRPLNLNNRNDISALEPKSYVIGGIEVKGAQYLDKDVLITISRLTVGEYIEVPSEQTANVIKFLMDQNLFEDVQLYATRIQDETIFLEIRVVERPRLTRVDLNGLSKSQTEEVRKRLNANTGKIVNENLLQTTKNTIEKFLREKSYLYPEIKITTKKDSAQSNNEIVVVDVERNKKIKVRKVEFEGNEEFSDKQLRKYLKGVKPRAWFRVFGPGKFKEDKYEEAKEKLVAKMQDKGYRDAQILKDSVYRYDNNEVAIDFDIYEGPKYYVGNIDWAGNAKYKDSVLNILLGIQKGDVYSEEKLNSKLSGPTRNSDDIAAIYQNDGYLTFNVQPVIKRIYQDTVDIEIQMFEGKQYTINNVILKGNDVTNDRVVLRSIYSKPGQKYSRELLVRSVREISQLGMFDEQKVTPMPTNLNYEEGTTDIEFTVAEKPSDQVELSGGYGAGQVIGTLGLTFNNFSTSNFFKKEAWKPLPRGDGQKLSIRGQTSGKRYQSYSFSFSEPWLGGKKPIYFGLSAYISNSQSQYYNPQTGRYEGYENNPKIQMHGVTATLGKRLQWPDNYFQINSSLSYQRYKLENYGNYFLFSNGTATNINFTQEISRNSIDAPIYPTSGSHLKFSVQLTPPYSAWNNIDYATAPDNEKYKWTEYHKWKFDSQWYTKIVGKLVLKTQAQFGYLGTYGDRTPTSPFERFKLGGDGMQGFDFLQGSEIIAMRGYANGTVIPATTGNNLQNIAIQSGSPIYAKYQIELRHPIMLNEQATVFALAFAEAGNTWNKFDEVNPFKVRRSVGVGARIFLPIFGMLGIDYGHALDPIPGLPTSQWKQNFTFSIIQNMGGF
>NZ_CP030848.1|WP_149526791.1|3380496_3381030_+|OmpH-family-outer-membrane-protein
MKRILVIVAMLAFMGSVSYAQKLAYVDSEYVMKHIPEYTNAQKQLDNLSQQWQAEVDKQYASIETLYKAYQNDAPRLNEDMRRRREDEIVNKEKSVKEFQRGKFGMDGELFQQREKLMKPIQDRVQKAIQDVARAQQYDFVLDKRSETSFLYANPAMDKSNEVITKLGLKPNASLAN
>NZ_CP030848.1|WP_149526792.1|3381127_3381685_+|OmpH-family-outer-membrane-protein
MKNLLKSVVVASGVLLAANTASAQQKIGHINTAEIVQSTPEFQAAEAQMKTLSETKQKELQGMYAEYQKKQNDANEKLRNRSEANKESVDAEVQQIANSMREMETRIQDVQRVAQEDIGKKQQELYAPIEQKVFTAINAVAQEKGYAYVLDVSNGGIPYFGGGDDLTADIKKKLGISATATPAKK
>NZ_CP030848.1|WP_149526793.1|3381767_3383459_-|GMC-family-oxidoreductase
MKSETNQFDVIVIGSGISGGWAAKEFCEKGFKTLVLERGRDVKHIKDYPTAYTDYWQFKHHNALSNAVRQENPIASKCYAFREDAMHFFTKDKDQEYIQEHPFDWIRGYQVGGKSLTWARQVQRWSDFDFEGPARDGFAVDWPIRYKDIAPWYSYVEKFIGVSGNRDGNAAMPDGEFLPAFDLNAVERMIQQKIPTKYPDRQVISGRCAHISSPQPIHIQQGRTQCQNRTMCQRGCPFGGYFSSNASTLPWAQKTGNLTLKPNAIVESILFDENSQKASGVRVIDAETLETTEYKAKVIFLNASALASNLILLNSKSARFPNGLGNDSGVLGKYIAFHNYLGSVGGSIEGFEDQYYYGRRPTQPIIPNFRNVKKQETDFLRGYASFFSAYRRRGVPSEMQVGADFKDSLTEVGGWGIGMMMQGETIPKESNHVRLSEDKKDKFGMPQLITSVQYDDNDQKSMEDFHNQAAEMLEYIGAKNIYKNNSQQNPGLDIHEMGGARMGNDPKTSILNKWNQMHLCKNVFVTDGASMTSTGTQNPSLTFMALTARAANYAMEEMKKNNL
>NZ_CP030848.1|WP_149526794.1|3383715_3385008_+|4Fe-4S-dicluster-domain-containing-protein
MIGQILFGVLLIASLILFFINAKKIYRNIKLGKSVNRFDRPSERLKTMLLVAFGQKKMFKRPIPALLHLFVYVGFCIINIEMLEIVIDGLFGTHRVFSFMGGFYNFLIYAFELLAFSVLLGCVIFFIRRNFLKLKRLNQSELNNWPKTDANLILTAEILLMAAFLFMNAADQKLQALGAEHYHIAGAFPVSSYLVNLLPDEVSSLILIERFCWWFHIIGVFAFLNYLPISKHLHILLAFPNTYFTRLEPKGKFDNMPSVTEEVKVMLDPSLPPPIGEASRFGVKDALDLTWKNLLDAYTCTECGRCTSSCPANITGKLLSPRKIMMDTRDRIEEIGKNIDKNGSFQDDGKALLDNYITREEIWACTSCNACVEQCPVNINPLEIIMGLRQYAVMEESQAPSSVNNMFSNLENNGAPWKYSQADRANWTNQ

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Crispr_ID: NZ_CP030848_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_18

3402583-3402684

Orphan

Consensus_repeat	Method
TCCTTAAATCCTTCCTTTCCTGGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_18

>merge|NZ_CP030848|18|3402583-3402684|CRISPRCasFinder
TCCTTAAATCCTTCCTTTCCTGGTTCAGAACAAACTTCCCTTTCTTGTGAAAACCAAACTCCCCTTTCCTGTTCCTCCTTAAATCCTTCCTTTCCTGGTTCA

>NZ_CP030848|18|18|3402583-3402684|CRISPRCasFinder
TCCTTAAATCCTTCCTTTCCTGGTTCA	GAACAAACTTCCCTTTCTTGTGAAAACCAAACTCCCCTTTCCTGTTCC
TCCTTAAATCCTTCCTTTCCTGGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526800.1\|3393194_3395387_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|130728
NZ_CP030848.1\|WP_149526813.1\|3411433_3411922_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|223872
NZ_CP030848.1\|WP_149526812.1\|3409586_3411356_-\|signal-peptide-peptidase-SppA	unknown	unknown	gnl\|CDD\|273226
NZ_CP030848.1\|WP_149526817.1\|3414821_3416549_+\|sugar-MFS-transporter	unknown	unknown	gnl\|CDD\|340952
NZ_CP030848.1\|WP_149526815.1\|3412249_3412948_-\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|224104
NZ_CP030848.1\|WP_149526808.1\|3401542_3402256_-\|2OG-Fe(II)-oxygenase	unknown	unknown	gnl\|CDD\|378278
NZ_CP030848.1\|WP_149526810.1\|3405055_3407866_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526809.1\|3403041_3404415_-\|magnesium-transporter	unknown	unknown	gnl\|CDD\|225148
NZ_CP030848.1\|WP_149526814.1\|3411914_3412277_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225108
NZ_CP030848.1\|WP_149526818.1\|3416791_3417655_+\|N-acetylglucosamine-kinase	unknown	unknown	gnl\|CDD\|225518
NZ_CP030848.1\|WP_149526804.1\|3398358_3398874_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236608
NZ_CP030848.1\|WP_149526811.1\|3408248_3409439_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP030848.1\|WP_149526799.1\|3390377_3392954_-\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|173589
NZ_CP030848.1\|WP_149526806.1\|3400243_3400960_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NZ_CP030848.1\|WP_149526805.1\|3398974_3399895_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|238921
NZ_CP030848.1\|WP_149526802.1\|3396344_3396956_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP030848.1\|WP_149526801.1\|3395379_3396348_+\|YpdA-family-putative-bacillithiol-disulfide-reductase	unknown	unknown	gnl\|CDD\|188533
NZ_CP030848.1\|WP_149526803.1\|3397059_3398076_+\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|234593
NZ_CP030848.1\|WP_149526816.1\|3413009_3414503_-\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|236490
NZ_CP030848.1\|WP_149526807.1\|3401287_3401539_-\|metal-binding-protein	unknown	unknown	gnl\|CDD\|376933

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526800.1\|3393194_3395387_+\|FUSC-family-protein	gnl\|CDD\|130728	TIGR01667, Uncharacterized_protein_HI_1680, integral membrane protein, YccS/YhfK family. This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane.	5.72097e-50
NZ_CP030848.1\|WP_149526813.1\|3411433_3411922_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	3.75184e-56
NZ_CP030848.1\|WP_149526812.1\|3409586_3411356_-\|signal-peptide-peptidase-SppA	gnl\|CDD\|273226	TIGR00705, Protease_4, signal peptide peptidase SppA, 67K type. This model represents the signal peptide peptidase A (SppA, protease IV) as found in E. coli, Treponema pallidum, Mycobacterium leprae, and several other species, in which it has a molecular mass around 67 kDa and a duplication such that the N-terminal half shares extensive homology with the C-terminal half. This enzyme was shown in E. coli to form homotetramers. E. coli SohB, which is most closely homologous to the C-terminal duplication of SppA, is predicted to perform a similar function of small peptide degradation, but in the periplasm. Many prokaryotes have a single SppA/SohB homolog that may perform the function of either or both. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.24306e-143
NZ_CP030848.1\|WP_149526817.1\|3414821_3416549_+\|sugar-MFS-transporter	gnl\|CDD\|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.22367e-32
NZ_CP030848.1\|WP_149526808.1\|3401542_3402256_-\|2OG-Fe(II)-oxygenase	gnl\|CDD\|378278	pfam09859, Oxygenase-NA, Oxygenase, catalyzing oxidative methylation of damaged DNA. This family of bacterial sequences is predicted to catalyze oxidative de-methylation of damaged bases in DNA.	1.18112e-110
NZ_CP030848.1\|WP_149526815.1\|3412249_3412948_-\|CDP-diacylglycerol--serine-O-phosphatidyltransferase	gnl\|CDD\|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	4.64343e-32
NZ_CP030848.1\|WP_149526809.1\|3403041_3404415_-\|magnesium-transporter	gnl\|CDD\|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	8.8726e-133
NZ_CP030848.1\|WP_149526814.1\|3411914_3412277_+\|hypothetical-protein	gnl\|CDD\|225108	COG2198, ArcB, FOG: HPt domain [Signal transduction mechanisms].	0.00298005
NZ_CP030848.1\|WP_149526818.1\|3416791_3417655_+\|N-acetylglucosamine-kinase	gnl\|CDD\|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	3.50047e-16
NZ_CP030848.1\|WP_149526804.1\|3398358_3398874_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236608	PRK09652, PRK09652, RNA polymerase sigma factor RpoE; Provisional.	3.97048e-40
NZ_CP030848.1\|WP_149526811.1\|3408248_3409439_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP030848.1\|WP_149526799.1\|3390377_3392954_-\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|173589	PTZ00398, PTZ00398, phosphoenolpyruvate carboxylase; Provisional.	3.56173e-165
NZ_CP030848.1\|WP_149526806.1\|3400243_3400960_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.62783e-26
NZ_CP030848.1\|WP_149526805.1\|3398974_3399895_-\|sugar-kinase	gnl\|CDD\|238921	cd01946, ribokinase_group_C, Ribokinase-like subgroup C. Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	3.95423e-147
NZ_CP030848.1\|WP_149526802.1\|3396344_3396956_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.33619e-13
NZ_CP030848.1\|WP_149526801.1\|3395379_3396348_+\|YpdA-family-putative-bacillithiol-disulfide-reductase	gnl\|CDD\|188533	TIGR04018, thioredoxin_reductase, putative bacillithiol system oxidoreductase, YpdA family. Members of this protein family, including YpdA from Bacillus subtilis, are apparent oxidoreductases present only in species with an active bacillithiol system. They have been suggested actually to be thiol disulfide oxidoreductases (TDOR), although the evidence is incomplete. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP030848.1\|WP_149526803.1\|3397059_3398076_+\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|234593	PRK00046, murB, UDP-N-acetylmuramate dehydrogenase.	4.52834e-170
NZ_CP030848.1\|WP_149526816.1\|3413009_3414503_-\|transcription-termination-factor-Rho	gnl\|CDD\|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NZ_CP030848.1\|WP_149526807.1\|3401287_3401539_-\|metal-binding-protein	gnl\|CDD\|376933	pfam02805, Ada_Zn_binding, Metal binding domain of Ada. The Escherichia coli Ada protein repairs O6-methylguanine residues and methyl phosphotriesters in DNA by direct transfer of the methyl group to a cysteine residue. This domain contains four conserved cysteines that form a zinc binding site. One of these cysteines is a methyl group acceptor. The methylated domain can then specifically bind to the ada box on a DNA duplex.	2.57815e-07

>NZ_CP030848.1|WP_149526808.1|3401542_3402256_-|2OG-Fe(II)-oxygenase
MENIEERIAGYDWAQLSDDLHQKGYATVPSLLTAEECEQLKSGYDDSSLYRKTIVMARYRFGLGEYKYFNYPLPNLIQMIRTSIYPKLAPIANTWFRVLNQDVQFPLEHDELLKRCRLNGQEKATVLILKYGPGGFNTLHQDLYGDVYFPMQLVLMLSEPDEDYEGGEFVLTQQIPRAQSKAIVLKPKKGDALIFTTNFKPEKGTRGYYRVNMKHGVSELRNGERYSLGIIFHDAST
>NZ_CP030848.1|WP_149526807.1|3401287_3401539_-|metal-binding-protein
MKQHVDLTDKELRAAIRGGNIQFGGNTKLKIYGLLSCSSGKRMKRANRVFFEKEEEALAEGYRPCGNCMRSSYQKWKQDTEKG
>NZ_CP030848.1|WP_149526806.1|3400243_3400960_+|methyltransferase-domain-containing-protein
MQNKSTLQEIEERFDKDVERFSNLETGQATMLDSAFNLDLITDCIQQHYPNLSSVLDIGCGAGNYDVKLLSRVTSNPSVHLLDLSQPMLDKAKERVSPLTQGEVKTFKGDFRTVDLVENSYDVIIATAVLHHLRDDNDWETAFVRLHRLLKPGGSIWIFDMIQQNTPKLQEIIYTQRYGNFLIHLKNEEYRDHVFAYIEKEDSPRPLVYQLNLLQQVGFRQVDVLHKNLCMASYVAFK
>NZ_CP030848.1|WP_149526805.1|3398974_3399895_-|sugar-kinase
MSLVIVGTVAFDAIETPFGKTDKIVGGAATYAGLAASYLYSDVKLVSVIGEDFGDDNLNIITSKGIDVEGLEIVPGGKSFFWSGRYHNDMNSRDTLITELNVLADFDPKIPASYQDCEYLLLGNLTPAVQSATLERLTNKPKLVVLDTMNFWMDVAMDGLKEVLKKVDVLTINDAEARQLSGEFSLVKAAEKILEMGPQYLIIKKGEHGALLFGEGQVFSAPALPLADVFDPTGAGDSFAGGFIGYLAKLQSINFANMKNAIIFGSALASFCVEKFGTERLENLTSEEIKARIQQFVALSKFEISE
>NZ_CP030848.1|WP_149526804.1|3398358_3398874_+|sigma-70-family-RNA-polymerase-sigma-factor
MNKLEFNTLVIKHSDSLKSYARNFTRDQDDANDLVQDTLLKAVTYFKNFRDGTNLKGWLYTIMKNTFINNYRRVVKTNTFITKEEEISQTNLVVSASKNKGENKFVMEDINYALSKLSDEYYVPFTMYFEGYKYHEISDHLKIPIGTVKTRIHVARKSMKKTLASYKFEAE
>NZ_CP030848.1|WP_149526803.1|3397059_3398076_+|UDP-N-acetylmuramate-dehydrogenase
MKNTLQTAVSLKDFNTFGIEAKANKYIRITEESSLKELYEQDAFKQKFFVLGGGSNVLFTEDYDGLIVHIANKGIQHFIEGNQVFVTASAGEVWNDLVWYCIKHDFPGMENLALIPGTVGASPIQNIGAYGTELMHIFYSCRAFDTHTGEFVTFTNVDCQFSYRDSIFKKEHKGRYIICSVTYKLSLFGQINTSYGAIEAELAKRNIQEPNIKDVAEVVSYIRVEKLPDPTTVGNAGSFFKNPIISKTQFINLQAQHPDIVHYPMGNDEEKLAAGWLIEQCGWKGKEVGEVAVWKNQALVLTNKGAASGAQIYEVSSKIVDDVLSKFGVKLEREVNVL
>NZ_CP030848.1|WP_149526802.1|3396344_3396956_-|TetR-family-transcriptional-regulator
MAKNADVKRQKILEAARRRFAHFGMAKTTMAEIAQDLSFSKALLYYYFPDKNRLYAAVLEYTVDEMVAETESRITKSKNIDEAFTAFLEARLEAIKENYSIFEYTYSLRNEFPPDLEEACTSIIDKDIEQVQNILSRGIEKGEIIVDDLPVTSKIFMISILGMRIGVVKEFNNIFIPPTKEEFDYILALQKKLARIFIRGLRP
>NZ_CP030848.1|WP_149526801.1|3395379_3396348_+|YpdA-family-putative-bacillithiol-disulfide-reductase
MDNYYDILIVGGGPIGLACGIEAQKNGLSHIILEKGCLVNSLYNYPVNMSFFSTSERLEIGDTPFVTTNPKPKRAEALEYYRRIESKFNLNTHLFEAVLSVNKDQGLFTVESSKQTYTAKYVVIATGFYDIPMYLHVPGEELPKVKHYYDDPHYYAKQNVVVVGASNSSIDAALETYRKGAHVTLVVRGPEISPRVKYWVRPDIDNRIAFGEIKAYFNSQITNITEDEVEIMTEEGLLTIENDFVLALTGYRPNFDFLRKVGIHIPAEAPMIPEHNPETMETNIEGLFLAGVVCGGLNTHLWFIENSRVHAQMILSRIKELN
>NZ_CP030848.1|WP_149526800.1|3393194_3395387_+|FUSC-family-protein
MKKTKEISNFFYSQYFADGLRITIGCVVPIIICAAFGEFLMGTFISLGALLIGLSDTPGAPSHRRTGMISCLIVCILTQLITVASNSNIWIMTIVIGLLCFLYSMFAVFNARAATVGSMGILIMLINVDDAYTFKEEMYFLLFFFIGAVWYMLISFSLSQVRPYRLAQQELSESIRFVGDFIRLRANFYDHKVDLDDNYRKLIEKQIEVHEHQENVRDLLFQSKRSIKDTTKVGRFLTLIFNDIVDLFEQSMTTHYDYEVIRKTYAHTGILKEFRNLLLKIANELDHLAYQLNANRAPKPLYNFKDDIESIKELIDQVEQKENINSIPLKKILISIRSITVFIHNIYNYNAIRSNKVNKQEIEEANKFIQTEHIVWSKLRDNLSFNSSIFRHALRMAVVMAVTYLVLNMDWFNVGSMGSYWVLLTIMVILKPGFGLTKERNFQRLLGTVIGGIIGAIILMTVHNEIALFILLIFFFLTAYSLFRVNYIVAVLFMTPYVLIMLSFTGYNTFEIAKERIFDTFLGGMIAFISSYVVFPNWESFQIRPNMRQLLIANYNYLAIAVRLLSDETVNITEYKLSRKEVYIASANMGSTFQRMLSEPKWRQKSTKEVNRFVILNHILSSYGATLLTQLQQAMNANYTKEHLLLLKKILSNMAKSIVLLTDDQDQPIFTEVSEFPEVTEETLDPAESKLITEQLQFLNKISADLYKSTVDVMEKEAIIHPQKIEMING
>NZ_CP030848.1|WP_149526799.1|3390377_3392954_-|phosphoenolpyruvate-carboxylase
MRLSQKKAAFQNEVLTRFDLFKSLFLTLPFQRVKHTGTILPFFTTHCEKGVEEKLTPEAIIDSFFGQYEQYVQEDDRLDLLFRIVQYIERQVVLFDAVEDSAFKAVGKSDETAGLDSVFRLAQSNPETKKQVIQRLRDMSVRLVLTAHPTQFYPGPVLSIINDLIELLKLNDIPNIHLLLQQLGKTPFINKLKPTPVDEAISLAWYLENVFYRVASEIQSKIDNELELSSAETSQIVELGFWPGGDRDGNPNVTWESTKRVATLLRTILFRCYYRDFRIVKRRITFRGVETYLDALQELLYENSFNPKENPEDITEEILFNLKEVKRVLLETHDGLFVEIVEDLIRKVQTFGCFFTTLDIRQDSSVLRETFNWLLTQYPKETGIDKKEIGDDEDAKEQAITFSEKDLAIENVPAPLVEDTLKVIRLIKQIQESGSERAVQRFIISNCQQASDILGLMQLFLWQGWSKKDLTMDFVPLFETVDDLSRAADVMRSLYANKAYAAHLKKRGNKQTIMLGFSDSTKDGGYLMANWSIYRAKIELTAISREFDVDLVFFDGRGGPPARGGGKTQRFYASMGKEIENNHIQLTIQGQTISSQYGSLDTAKYNIEQLLHAGIVSDLRQKEGDTLTAKQKKVIDQMAAESHKKFLSLRKHPKFLKYLETLSPLKSLASINISSRPVKRNSDKELRLEDLRAISFVTAWSQLKQNIPGFYGVGTALQWAEDNNMWSYVKNLYENSGMFNTIIDNCMMSMTKSNFNITSYMQDDAEFGEFWKMLKDEFDRTKEYLLKLTGMTELMENYPVEKASICEREKIILPLLIIQHYAIRKLESNKLDEKKADVYRKLIGRTIYGVVNAGRNLA
>NZ_CP030848.1|WP_149526809.1|3403041_3404415_-|magnesium-transporter
MEELAMLVAHVEQLIERGDQAELADYLNELNISDVEELIDELPEHGPLFLETLSLKRAVNVFRILDFPTQERIFKKLKATTIRELLNEMPPDDRTSFFSELTGDVVKRLIILLTPEERKEALSLLGYPEDSVGRLMTPDYITVKEHWTMQRVLDHIRRYGGASETIDVLYVIDAEGKLMDDVRIKDVLLADPETVVSDLIDNRLISLRANDPQEEAVSIFRMNNRVALPVVDDRDIMLGIVTIDDILWVANEEYSEDMQRIGGTEALDEPYLDVSIFHLVKKRAGWLIVLFLGQLLTVTVLNHYEDKLTTVLVMLMPVIMSSGGNSGSQASTLIIQAMAMGEVTLRDWWIVMRREILSGTLLGVILGGLGFFRISVEEAFRHTYGDLWYLYGCAIGLSLVGVVLWGSLVGSMLPFILRRCGADPASSSAPFVSTIVDVTGLIIYFTFATLILKDVLF
>NZ_CP030848.1|WP_149526810.1|3405055_3407866_+|hypothetical-protein
MKLIIRYLTALTLTINTVSVFGQLIDNEQPHSSVKWEQINRPNFQLIFPQEFRNSASLLAHRIDSMLVLASEDLGRKPKKISIILHENHIEQNGFAQLAPRKVEAFSTPGPASDNQEWLPNLIQHELRHVAQFDKLTGKMSGPFLEQLALAFYGIHLPAWYFEGDAVSIETQFSSGGRGRLPSFLMPLRTNEMTGKTYTFDKNILGSFRDITPSYYLTGYLMNTYLTNHFGYPVKGQIMEDMRRHLLRPYNFNRALRKATNMNSHDLYKATISDLRSTWEDSGKLPSQAEIRPNYQRYFSHLFLPQSDGSDAIFYLFQSPQEVKQFREWSNGKEKTLLKIGYQLTPYFHQSGDFIVWDEIRKDGRFGKQTYNIIRLYNIKTGLSESLSRDSRLYSPIIDAEKGGIYAIQVDQDNAASLVYIDIISKEQSKIIDFPVGILVQQPALNDKKDKIVAIAVSEKGTNLMEIDLQTKATSLVFPWSNQQFERPIYAGEDLIFKAHFDQIDNIYRYSKRENKTYRISNSAFGAFYPSLSTDGNLLYNEYQNDGYRLAKLKLRNENQEEIKPVFEAPAITDQQISGTFSNKLKVENGDFEVEKYNTLSDFFNFHSLSISANNFEDFDNYKPGIFWLANDLMNTSQLKLGYEYDMDIEKSIYSAELVYQKYYPKFIAKYQNRGRIGYAKSSNPNAETIQFDYRDHYYSFEMQLPFSLYRGNNIYSFGLNVGTSYQKNYDLSINNLKNFNEEIILPMNYIAYFNRNVRRSSMDLVPRWGQNISIIYRHLPFENELDGNLFAIKSNFFFPGFFANHAFQARFNYQDNTGRFDNSYEIPMISAFGHFKSGKVSNNLMLNYRFPIAYPDWTIGSLAYIKRFHGYFFADYQNLHNSDIAPKTYGIGLSVDLNIFRYKLPDFGIGSKLSYINDASATNKIVPSFSFSYSY
>NZ_CP030848.1|WP_149526811.1|3408248_3409439_-|phosphoglycerate-kinase
MKTIDDLNFNGKKALIRVDFNVPLDENFNITDDNRIQGAAPTIKKILKDGGSVILMSHLGRPKEGPTDKYSLKHIVKHLSDVLGVDVQFADDCIGQEAIDKAAALESGQVLLLENLRFYKEEEKGDRDFAEKLSKLGDVYVNDAFGTAHRAHASTAVIAEFFPNNKYFGYLMAREIENAEKVMNKPERPFTAIMGGAKVSDKLELIEALLDKVDNLIIGGGMAYTFIKARGGEIGKSLVELDKLDLANELVKKADEKGVNLVLPTDAQIADRFANDANVYDGPNDEIPADMQGLDIGKESSEHFHDVIMASNTLLWNGPMGVFEMDTFAKGTKAVADAVVAATERGAFSLIGGGDSAAAVSKFGMTEHVSYVSTGGGALLEYMEGKTLPGVKAILD
>NZ_CP030848.1|WP_149526812.1|3409586_3411356_-|signal-peptide-peptidase-SppA
MKSFFKYVLATITGIIISSILMFFILIGIVTYMVSSVSPTSETVTPSNAVLLVTLDHTITEKTEPNPFEGLDMPGYSSMRSIGLNDILSRIQAAKEDSNIKGIYLNVKGVNTGFATMKAIRDAIQDFKASGKFVVAYSESFTQKAYYLSSVADQVYLHPEGGLDFRGLASSVMFFKDALDKVGVDMQVLKVGTYKSAVEPYIMNSMSEANREQVNSYLGSIYNTFVNDIATGRKLNADSIRGIADNYAIKYPEDAVKLKFVDSLLYKDEILAKIREKLGIDSKKDIPTISLLDYKNTPSTGKGTADRVAVLYAYGAIVDGEGSTGMIGGDKLSRDLRELRNDDKVKAVVLRMNSPGGSALASDVIWREVELTKKVKPVIVSMGDYAASGGYYISAAADSIFADPTTLTGSIGVFGVIPSFQKLFNEKLGVHFDAVKTGKFADMDVDMDRPLTEEEKSIIQGSVNRVYQVFMKRVADGRKMTVANVDSIGQGRVWTGAQAVELKLVDRLATLDEAVKAAAAKAKLTDYRVTEYPRAKDPLSEIWSVSKEKVKGMLIDEELGEYAKYLKELKRVTTQSGIQARIPYMIEIY
>NZ_CP030848.1|WP_149526813.1|3411433_3411922_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MNIVYLLTGANIGNPRQQLNDAKIEIAERVGKIIKESSIYESEAWGVEDQPIFLNQVLEVITTHSASKVLQTIQQIELVLGRIRTQRWGSRTIDIDILYYNTDIIHEPDLQVPHPYIQERNFTLIPLTEIAPNFEHPIFKKTNQQLLMDSKDPLNVNIAKHE
>NZ_CP030848.1|WP_149526814.1|3411914_3412277_+|hypothetical-protein
MSDFKIINPDVLKSSMMNNMEMVKQLVALFLTQGKVDFETLENAVNEKNYLEIASKAHHIKPTMEYIGASNLRIQFQDLEQKARNKASIEEIEEAFAILTRDFNTAMLELETYSTSLAEA
>NZ_CP030848.1|WP_149526815.1|3412249_3412948_-|CDP-diacylglycerol--serine-O-phosphatidyltransferase
MKKYIPNSITSLNLFSGCIGVVMALQGNYLFAFYCVLASGIFDFFDGMSARALHVKSLIGKELDSLADVISFGFLPGTIMFMMLKESTDSQYLPYLGYVMTIFSALRLAKFNIDTRQTTDFIGVNTPMNTFFIISLPFIAQDYPLLHNVVLLLGIVAVCSFLLVSEIKLFSMKLSSLAWSANKFKYLFLLLSLVLIVIFKFLALPMVLILYILFSYLHFASERNYASAKEVE
>NZ_CP030848.1|WP_149526816.1|3413009_3414503_-|transcription-termination-factor-Rho
MDINELNTKLVSELREIAKVLGIVDAEKLRKQELIDRITVIADEAQQDSTAPAADSDSADHASGDRPRKRVRTVKSAEPIAVTRKPSSTEETPRVEQAVATEVEVAEAPKPAAPAEPAPAKSSSADFDNVIVNEGVLEIMADGYGFLRSSDYNYLTSPDDIYVSQSQIKLFGLKTGDNVRGCIRPPKEGEKYFPLVRVEAINGQDPAEVRDRVPFDYLTPLFPDEKLNLDLGPGNYSTRIMDLFTPIGKGQRGLIVAQPKTGKTNLLKEVANAIAKNHPEVYLIILLIDERPEEVTDMARSVRAEVVSSTFDEPADRHVKIANIVLEKAKRMVECGHDVVILLDSITRLARAYNTVAPASGKILSGGVDANALHKPKRFFGAARNIENGGSLTILATALTETGSKMDEVIFEEFKGTGNMELQLDRKLSNKRIFPAIDLTASSTRRDDLLVDREELQRLWVLRNHLADMNSQEAMEFLLTQMRGTKSNQEFLISMNG
>NZ_CP030848.1|WP_149526817.1|3414821_3416549_+|sugar-MFS-transporter
MSNHPTNTETKTNYPALYTLIVVFFFWGFIAAGNSVFIPFCKNYFHLDQFQSQLIDFAFYSAYYIGALLLFIFGTLSGKDLVGKWGYKKSIVYGLLFSALGAASMIVAVEVNLYVGMLIGLFIVALGFSLQQTAANPFAVILGDPKTGASRVNLGGAVNSLGTTIGPLIIGYALFGTFETVSDSEIASLPLNKVVYLYIGVGLLFILAAALFNFSKKVPAGYNLEQMESANKARTTLIIITVLLLCAFVPVFTSYKSDAALEVAALQEQIQASNDAGLIAKAKELTHGLEISRMFWLLGALVVVVGGLLFAYTRAQKNPIGWGAMKYPQLVLGMLALFVYVGIEVAIGSNLGELLTLEEFGNLQSSQITPYVSMYWGGMMIGRWAGAIAAFNFTSSKKQLLTIIVPIIAFSIIIGVNTLAGFDMSVLYYYIICVAVQIIAFFISKDKPVRTLVIFGTFGLVAMIVGLMTSGTVAIYSFLAGGLACSIMWGSIFSLSIVGLGKYTEQGSAFLVMMILGGGIIPPIQGKLSDIIGIHNSYIVPVIGFIYIILFAFLVRGFLTKQGINIDDVESEGTH
>NZ_CP030848.1|WP_149526818.1|3416791_3417655_+|N-acetylglucosamine-kinase
MIIIADGGSTKTNWCLLDDSNKKIYFNTEGYNPYFVDSDYIVASLKKGLPHDIPFEKIAEVNYYGAGVHNEEKAKIVEEAIQAVFPNAKVEVGHDLLAAARALLGNEAGFAAILGTGTNTCIYDGKDITHNIDSAAYILGDEGSGSYIGKKLLTDFIRGLMPKDVADVFYETYKLTPDEIMDNVYTKPLANRFCASFSKFVYDNNVNIQYTRKIVDDAFEAFFNNLVSKYPDYQSYTFNCIGSVGYNFRNVLEEKANQYGMQVGKILRSPIDDLVQFHINRSKTTAN

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Crispr_ID: NZ_CP030848_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_19

3429684-3429802

Orphan

Consensus_repeat	Method
GGTCTAATATCTAACATCTATTGTCTAATGTCTGTTTTGAACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_19

>merge|NZ_CP030848|19|3429684-3429802|CRISPRCasFinder
GGTCTAATATCTAACATCTATTGTCTAATGTCTGTTTTGAACCAAGAAAGGAAGGATGCAAGGATGAACAGGATCAGGTCTAATATCTAACATCTATTGTCTAATGTCTGTTTTGAACC

>NZ_CP030848|19|19|3429684-3429802|CRISPRCasFinder
GGTCTAATATCTAACATCTATTGTCTAATGTCTGTTTTGAACC	AAGAAAGGAAGGATGCAAGGATGAACAGGATCA
GGTCTAATATCTAACATCTATTGTCTAATGTCTGTTTTGAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526819.1\|3418501_3418819_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|376829
NZ_CP030848.1\|WP_149526828.1\|3431536_3432541_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234993
NZ_CP030848.1\|WP_149526823.1\|3423602_3424112_-\|redoxin-family-protein	unknown	unknown	gnl\|CDD\|238207
NZ_CP030848.1\|WP_149526835.1\|3440237_3441077_+\|sulfurtransferase	unknown	unknown	gnl\|CDD\|225450
NZ_CP030848.1\|WP_149526827.1\|3430055_3431048_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149526622.1\|3419577_3421026_+\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|377531
NZ_CP030848.1\|WP_149526825.1\|3425244_3427896_+\|peptidase	unknown	unknown	gnl\|CDD\|349459
NZ_CP030848.1\|WP_149526822.1\|3422837_3423437_+\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
NZ_CP030848.1\|WP_149526832.1\|3434942_3435914_+\|YihY-family-inner-membrane-protein	unknown	unknown	gnl\|CDD\|377085
NZ_CP030848.1\|WP_149526829.1\|3432680_3433484_+\|PASTA-domain-containing-protein	unknown	unknown	gnl\|CDD\|225372
NZ_CP030848.1\|WP_149527742.1\|3417807_3418491_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_CP030848.1\|WP_149526836.1\|3441126_3442005_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP030848.1\|WP_149526834.1\|3438213_3440148_+\|30S-ribosomal-protein-S1	unknown	unknown	gnl\|CDD\|235775
NZ_CP030848.1\|WP_149526831.1\|3434531_3434942_+\|YbgC/FadM-family-acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP030848.1\|WP_149526824.1\|3424118_3424982_-\|N-acetylglucosamine-kinase	unknown	unknown	gnl\|CDD\|225518
NZ_CP030848.1\|WP_149526826.1\|3428367_3429360_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149526821.1\|3421489_3422623_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP030848.1\|WP_149526820.1\|3418932_3419427_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526833.1\|3435955_3438121_+\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP030848.1\|WP_149526830.1\|3433488_3434529_+\|endolytic-transglycosylase-MltG	unknown	unknown	gnl\|CDD\|376862

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526819.1\|3418501_3418819_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	4.1663e-21
NZ_CP030848.1\|WP_149526828.1\|3431536_3432541_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	3.21196e-114
NZ_CP030848.1\|WP_149526835.1\|3440237_3441077_+\|sulfurtransferase	gnl\|CDD\|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.21332e-78
NZ_CP030848.1\|WP_149526827.1\|3430055_3431048_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.76424e-17
NZ_CP030848.1\|WP_149526622.1\|3419577_3421026_+\|IS1182-family-transposase	gnl\|CDD\|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	6.73829e-13
NZ_CP030848.1\|WP_149526825.1\|3425244_3427896_+\|peptidase	gnl\|CDD\|349459	cd06240, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	8.25607e-110
NZ_CP030848.1\|WP_149526822.1\|3422837_3423437_+\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	3.94265e-85
NZ_CP030848.1\|WP_149526832.1\|3434942_3435914_+\|YihY-family-inner-membrane-protein	gnl\|CDD\|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	4.9826e-47
NZ_CP030848.1\|WP_149526829.1\|3432680_3433484_+\|PASTA-domain-containing-protein	gnl\|CDD\|225372	COG2815, COG2815, Uncharacterized protein conserved in bacteria [Function unknown].	2.30767e-19
NZ_CP030848.1\|WP_149527742.1\|3417807_3418491_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	2.80124e-87
NZ_CP030848.1\|WP_149526836.1\|3441126_3442005_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	6.70645e-71
NZ_CP030848.1\|WP_149526834.1\|3438213_3440148_+\|30S-ribosomal-protein-S1	gnl\|CDD\|235775	PRK06299, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP030848.1\|WP_149526831.1\|3434531_3434942_+\|YbgC/FadM-family-acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.03636e-39
NZ_CP030848.1\|WP_149526824.1\|3424118_3424982_-\|N-acetylglucosamine-kinase	gnl\|CDD\|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	2.22592e-09
NZ_CP030848.1\|WP_149526826.1\|3428367_3429360_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.61468e-17
NZ_CP030848.1\|WP_149526821.1\|3421489_3422623_-\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	1.91377e-06
NZ_CP030848.1\|WP_149526823.1\|3423602_3424112_-\|redoxin-family-protein	gnl\|CDD\|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	3.55486e-79
NZ_CP030848.1\|WP_149526833.1\|3435955_3438121_+\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.72437e-51
NZ_CP030848.1\|WP_149526830.1\|3433488_3434529_+\|endolytic-transglycosylase-MltG	gnl\|CDD\|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	1.28228e-96

>NZ_CP030848.1|WP_149526826.1|3428367_3429360_+|transposase
MKKDRITLGVDVSKKTLDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLEPSGKLNSAIFDLKQLISFRKRLVRAMAGYKASSSERKAMYGKDAGKVIQQVSKTMIDVCKKEIYKVEREILQLIESDESLNRNYQILKSVKGIGPINAWMTIVYTENFKAFTDPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYAQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149526825.1|3425244_3427896_+|peptidase
MKHLKASLWLLLLLVGMSVQSRAQQISSPKTHFGFEIGDDYQLANFEQTEKYFKKLSEQSDRVIYQPIGKTEEGREQCMLIISSPENLKDLEKYKQISSQLARAEITEQEARNLSKEGKSVVWIDGGLHSTEVVGMHQLIQTAYLLASATDAETEHILQNSIILLVHANPDGQDLVSNWYMREKEATKRSTSLVPVLYQKYAGHDNNRDFFMLNLKESQNMARQLFVEWVPQIMYNHHQTAPAGAVVAGAPYRDPFNYVFDPLLMSGIDALGAAMSSRLNAENKPGYTAKGGSVFSTWYNGGLRTTTYFHNMIGLLTEIIGNPTPYDIPLVPSRLIPSSNTQNPVLPQRWHFRQSIDYSISLNYAVLGYAARYRDEVLYNIYRMGRNSIEKGNKDTWSLSPSKVAIVEQAVQNARKANPNERFPDANLVNKLYEDKALRDPRAYVIPANQAEFNTAVKFLNALIGNGIEVMKATADFTAAGKSYPEGSYIVKTNQAFRPHILDMFEPQDHPDDFEYPGGPPIPPYDAAGWTLAYIMNVKFDRFLDDISGPFQKLPIGEQIILEKNASAKSKFLSLPAANNDSYQIVNSLLNNKQKVWRDQDNGNFYIANTNNLSLNIPSTAVNAIPKSAKALKTLRIALWDSYGGSMPSGWIRFLMEQFDYNATVVFPPDIDKGNLNDKFDVIILPGGSIPRLQIGAGLGYGPNFNNAAPENIPSPYRERWGRLTAEKSIPVLRDFMEKGGTIVSIGNSFDIAKHFNLGITDALVDADNKPLRREDFYTPGSVLQAKVATNLPDTWGYDEDIDVYYSNSALFKINDQQIKPLIWFDSDQVLKSGWSWGEKYLKDAVLAFDAKIGKGKLVCFGNDITFRAQTHGTFKFLFNQLY
>NZ_CP030848.1|WP_149526824.1|3424118_3424982_-|N-acetylglucosamine-kinase
MILVADSGSSRSDWMLHLPDSKPLQFRTKGLNPFFVNEKEIASVLGQVQEIIPYIKEINEVYFFGAGCTTPDRRELVSNALTEIFPNSFISVESDLVGSAYATFGNNQGLICNIGTGSDISFYNGDTLEQGVHGIGYVLGDEGSGAWFGKQLITAYLYEQMPRDLMRIFKEAHPITKDIIIKNVYQRDRPNAYLASFAEFMAANRTHPYIDNLLRNGFDEFVRTNVMTYPEFWEYECHFVGGIAYHFDLHLREVCNLHGVRIGKILKNPIEEIFHFIVNRELNVEFN
>NZ_CP030848.1|WP_149526823.1|3423602_3424112_-|redoxin-family-protein
MLVKMILLYTMLFQQPSVYDYSFNTIDGKKVSLADFKGKELLIVNTASKCGFTKQYKELQELHKQYGDKLVVIGFPSDNFGGQEFDVNEKIQEFCEQNYGVTFLISEKVDVKGEKAHPLFKYLTSAQNEDFTGDIKWNFEKFLINKDGRLTNRYRSKVTPLDESIVSKI
>NZ_CP030848.1|WP_149526822.1|3422837_3423437_+|thymidine-kinase
MMLFSEHNFHERQERVGSIEVICGSMFSGKTEELIRRLKRAKFAKLPVEIFKPEIDVRYGDKEVVSHDSNAIPSTPVSHSSAILLLSSDTKVVGIDEAQFFDDELPEVCNTLANRGIRVIVAGLDMDFKGRPFGPIPNLMAMAEHVSKVHAVCVQCGSPATYSYRFAENESRVLLGEKESYEPRCRACYFRENKNDEQS
>NZ_CP030848.1|WP_149526821.1|3421489_3422623_-|hypothetical-protein
MAYSQQDIYNKIGDLLVEINEQYASLDKAKLTQDSVQVQLMAAQAKFLAANLDALNQLSAPAIVAAVPELPGTENTVAEEENTFTPAPTFDEHEADSQPVIEEIQEVKSEDVIEETEVVAEAPEEVEEEEQSPEQKTEGIKFEGFGHIDDSVTDNETDQEEAAVVENIEDTVEEEEQEEEVKAVEERPEEPAAPAYTHTASSNYTSVERPTNSFKTQAPVEEKKEEVSNEPVVNEVVIEEKHVEIKEEPKEASLNDLAKQAEQTPSRRMTLNELIQQQKQAGLTNVNQFQTSTSKSSDTIVDLKTGVSLNDKLLFIKDLFNGYSLAYSEAIELLNRFDNFAEADAFLQSNYALKNNWASKPQTVDKLYVVLRKKYVS
>NZ_CP030848.1|WP_149526622.1|3419577_3421026_+|IS1182-family-transposase
MLSTQQKIQFSSYSGLYDIIVPKDNLLRKINDLIDFSFIYDELLAKYCQTNGRTAESPIKMFKYLLLKTIYTVSDVDVVERSRYDMSFKYFLEMAPEEDVINSSSLTKFRKLRLKDMDLLNLLINRTVTIALEKGIIKSKSIIVDATHTVSRSNPHTALAVLRERSKLLRKAIYQIDGEYKRNLPQKNESNDLDQELAYCRELQRVLDEDQSISEIPAVKEKLNLLKETIEDTKEYYLLSKDDEARLGHKSVDSSFFGYKTHLAMTEERIITAAVVTTGEKGDGPELPRLLEISQQNGMQVDTIIGDAAYSGKENLQVAKEQNIDIIAKLNPSITQGFRKDKDKFDYNKDADMFVCPAGHLAIRKARQGKKEQGTNQTETYYFDVEKCKVCPLREGCYKQGARTKSYSVSIKSELHREQMAFQQTDYYRSKSKQRYKIEAKNSELKNVHGYGRADAYGIHNMEMQGAMAIFTVNLKRILKLI
>NZ_CP030848.1|WP_149526820.1|3418932_3419427_+|hypothetical-protein
MNELTYYTEISEDLQKNNPTAYEELDEEIHIIIHKLKFIPLESRPIVQVISNDESIQQDYLQELLKVAGAQPIASAVPLEDVEILIFIDETNNYLSTLPVELQTLYAESKAVKNNQIYIIQKSAFAKDKAAYIQDIEVLAEIVQSKYFVFGHEGEEWIKFDIRY
>NZ_CP030848.1|WP_149526819.1|3418501_3418819_-|YbaB/EbfC-family-nucleoid-associated-protein
MFDKLFQAQQKAQEIKDRLDHVSVSGEAEGGKIRVIASANKEIKEINIDPEFLKDADKEELEELLIVALNKAITQAESISQAEMAAASQDMLSGLGGLGNLFGNK
>NZ_CP030848.1|WP_149527742.1|3417807_3418491_-|metal-dependent-hydrolase
MKLTYYGQSCVEFDFNGTKVLVDPFITYNPLASSINVADIRADYIFLSHGHQDHVADMATIQKQSDATVCAIVETAAWVRKQGVADDKVIEYNIGGTLKLPFGKVKMVYAVHTNSTPDGEYGGFPVGYVFFVDGKTIYFAGDTALTMEMKLLERFNIDLALLPIGGHYTMDAEDAVIAADFIKCKHIVGIHYDSFPPITIDKEATKSIFDAAGLELRLPKIGETITF
>NZ_CP030848.1|WP_149526827.1|3430055_3431048_+|transposase
MKKDRITLGVDVSKKTLDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLEPSGKLNSTIFDLKQLISFRKRLVREMAGYKASSSERKAMYGKDAGKAILKVSKTMIDVYKKEIYRVEREILQLIESDESLNRNYQILKSVKGIGPVNAWMTIVYTENFKAFTDPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYTQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149526828.1|3431536_3432541_-|D-alanine--D-alanine-ligase
MKTKVALVKGGYTGEAEVSFKSAAFVYSQIDKDKYDVYPITISLDSWFYEDEQGAKHEIDRQDFSLELAGNKVTFDVAFIIIHGVPGEDGRLQGYFDMIGLPYTSCTALTSALTMNKGYTKAIVQDIPELNVAKSVLLFKEHRPVSVDMVTEKLSLPIFVKPNAGGSSIGMSKVSEWSALKQALDNAYDAENTGYQVLVEEFVNGREFSQGIYRDAKGELQVLPATEVRTTREFFDYEAKYTPGLTEEITPADLNTEQKERADRLIKEIYIRLNCKGMVRIDFFIENNTDKFFFIEINTVPGQTAQSFIPQQVRASGRTETAFYGELIEAAMGE
>NZ_CP030848.1|WP_149526829.1|3432680_3433484_+|PASTA-domain-containing-protein
MSKFFLYLRTSTFRKNLIAALIFIVVLFVVVYFGLKIYTKHGDSQEVPVLKGLHINEALKILDNAGLEYEVDSIYQMDAKPGLVIDQDPDPKSHVKGGRTIYLTIITQSAPEIAFPEIVDKTFIEASAILKNHSLKIADTTYINDIARDVVLEVKFSGQVIQPGRMVPKGSRISLVLGNGRGDSEVDIPNLVGQSVEEAKFALAGLGLTLGSISFSDNSRDTLNARIVSQSPDTSTHVISIGSAVHVTLAMPTAAPATPVNPTTPQN
>NZ_CP030848.1|WP_149526830.1|3433488_3434529_+|endolytic-transglycosylase-MltG
MSENRKKNSALKVILIIILVVGLAVAWIGYRAFIAPSIATSEEYFYVHTDEPYESVIKRIEDEGIVKNPSYFNYVARAMDLQTGIKPGRYKLSKDLSNRRFIGNLRGGYQEAVPFRFQNLRLKENFAGALGKNFEADSTTFLNLLNNEALAEKYGFNKDNFFLMFIPNTYEIYWNTKPEEIIDRFSKEYAKFWNADRKAKAAALNMTPEEVSVLASIVKGEALHVDEMPEIAGLYINRLKRGMLLQADPTVIFANNDFTIRRVLNRHLTIDNPYNTYRYKGLPPGPIMMPSIASIDAVLNYNQHEYIYMCAKDDFSGYHNFAKTVAEHQVNARKFQQALDARNIKK
>NZ_CP030848.1|WP_149526831.1|3434531_3434942_+|YbgC/FadM-family-acyl-CoA-thioesterase
MFSYKHQVRVRYAETDNMGYVYYGNYAAYYEVARTEMLRSTGISYKELEDMGVMLPVIELHCQYIKAAKYDDLITINIYIREKPGIRIKFEYELFNEEGELLNTGSTQLVFVDMERNRPCRPPAIFQEKMAPFFGE
>NZ_CP030848.1|WP_149526832.1|3434942_3435914_+|YihY-family-inner-membrane-protein
MKKVHQTLLHLQPYDRLIEWSKSATLPGFGKLPLYTVFVFFFQEISRESIINKASSLAYNFMLAIFPGIIFLFTLIPYIPIDNFQEQLMDLIQLALPDNAYQVLENTLKDIIIRQNGGLLSAGFVLCTFFATNGMTTLMMTFNKSSLSKESRTWFQRRIVALVLSFSIVFALICGIVLYMGSNFLINYLKTHIDYDLSWFWSFLIKTAQWLILFSIYFFTVSLIYKFGPSSSRWKLFTPGATLATLLAMLSFSLFTFYINNFGAYNKLYGSIGTLIVVMIWMYMNALILIIGYELNASIALSKQSIKIVKPRVYNSFKANQAE
>NZ_CP030848.1|WP_149526833.1|3435955_3438121_+|response-regulator
MQQEDKYLVDRTKRNKSIRNILLLSTIGLFVAFLIFFISSFIQYRSIQSRIERIYSSINTDQTSFVTLLTKFNDAENHFRQYSLNYDSTDFLEYNKNLMLLRASVDSLRKVREVEEIVDQKYRSDSIDYSRLLPMYIDLAANIDSLMQSARTLDEFHRTAINNSMFNLPQENSIANSDLSRSTPSVIINRKPLLQRIFQPKPDTLTLGSDLLSQDTRNMLHQSFSRIRSESDARAQGKLDEIKLQLTDLRQKERLMLADNFTLLHKTNQQIRFVYDQRIKFQREKSDQELNVLLANTDTFKWQIIVSLTFVFIVICILVYYQFFTNYYEQMLMDEKIYASKLAEQKTDILAEITHEIRTPINSMIGIVDLLRSRNDLYQPKDILLLETAYSNITATSKTINDILNLSKIDKHDTIEPNHFDFHDMLLEILDNYRNQASLKKITLNHSLDESKPTIIFTDELKVRQVVSNLVSNAIKYSSQGTVTTKMYVNNHSNLVIKVSDEGNGIPENLKKNIFKKYYTENKTNKVEGGVGLGLYITKNIVTLLKGKISFQSRANQGTTFTVEIPIPRPKFRRKNTLNIHQVRDLPKNLSWLIVDDNALNLLYLKQFFLLHEQVYTATNGLEALNLMETKAVDVIVTDINMPVMTGDELLVKVRQNPAYERVKIIATSSDNEQVKKQEGIRRMKFDGILIKPFNEKKLTEVILKTLYPIFEDSDEIQQEG
>NZ_CP030848.1|WP_149526834.1|3438213_3440148_+|30S-ribosomal-protein-S1
MAKKQEAEKELAAKNAELQGADTKVVKDTEKIESEADSNLIDEIKSNTWSTPSGDFDWDLDEKAFGNYSEAERVKLEEQYAGTFNQINQGEIIEGIVVSINNKDVVLNIGFKSDGLVALSEFRDLPDLKVGDTVDVFVESQEDANGQLVLSRKRAKTQKSWEEINAALENDAIIDGFVKSRTKGGLIVDIKGVEAFLPGSQIDIKPIRDYDVYVGKTMEFKVVKINHEFKNVVVSHKVLIEDDLENQKSEIVAKLEKGQVLEGTVKNITDFGVFIDLGGVDGLLHITDISWGRIEHPKEVLALDQTINVVVLDFDDEKKRIALGLKQLSEHPWESLDTGLEIGSKVKGKIVTVADYGAFLEIIPGVEGLIHVSEMSWSQNLRSPQEFLKVGDEIEAVILTLDREERKMSLGIKQLTPDPWQNITERYPVGSKQSAVVKNMTNFGVFVELEDGIDGLIHISDLSWSKKVNHPNEFTKVGERLDVVVLELDEENRKLSLGHKQLEENPWDTFETIFTEGSVHEGTVIKVGDKGDIVALQYGVEGFCPNKHSVKEDGSSLKVDEVAEFKIIEFNKENKRLVISHSRIWEDAKAEARIEEFNARKKEAKAASSAVRKVKDNVEKSTLGDLDVLAQLKEQMEDNEKKSK
>NZ_CP030848.1|WP_149526835.1|3440237_3441077_+|sulfurtransferase
MNRALIDIEQVQNFIKEHADRVIILDASIDKVGQKLDNNNLELIPNSHFFDIENAFSDKAINLPHTMVDASTFENEARKLGINEDSIILLYDRWGVYSSPRAWWMFKYMGFDQVYVINGGLPAWKSADLPTVDSYAAVEQTGNFIAKPNSEWIIKIDELKELVGEADVHITDARSAGRFSGAAPEPRPGLKSGHIPGSKNIPFDQVLDGAYFRSNEQIAPLYADKSFSSGQNIFTCGSGITASILALGAYELGYPHIRVYDGSWSEWGSDPDTIVDQNI
>NZ_CP030848.1|WP_149526836.1|3441126_3442005_-|pirin-family-protein
MSNIDFIREETAADIGNFLVGRLLPFRQKRSIGPFVFIDHMGPACLADHENLDVGLHPHIGLSTLTYLFEGSIFHRDSLGTAMEIKPGAVNWMTAGKGVVHSERTPEYLRQKDKFLHGLQIWVALPKELEFQEPEFHHVEADAIPAWEADGVSYKLIAGEAFGKKSPVPVHSKLYMIEIKTTKDALIDIRGELYGESGLYILEGEIESNGYTYGPKQILITLDAHLCSFEMKAGTTVYIFGGEPFPEERFIYWNFVATSKEIIEEAKQKWINHEFPKVPGDDGYVPLPAARK

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Crispr_ID: NZ_CP030848_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_20

3431286-3431391

Orphan

Consensus_repeat	Method
GATCCTGCCATTCCTTAAATCCTTCCTTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_20

>merge|NZ_CP030848|20|3431286-3431391|CRISPRCasFinder
GATCCTGCCATTCCTTAAATCCTTCCTTTCCTGGTTCAGACTAGATATTAGACAACAGACAACAGACATTAGACCCGATCCTGCCAATCCTTAAATCCTTCCTTTC

>NZ_CP030848|20|20|3431286-3431391|CRISPRCasFinder
GATCCTGCCATTCCTTAAATCCTTCCTTTC	CTGGTTCAGACTAGATATTAGACAACAGACAACAGACATTAGACCC
GATCCTGCCAATCCTTAAATCCTTCCTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526828.1\|3431536_3432541_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234993
NZ_CP030848.1\|WP_149526819.1\|3418501_3418819_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|376829
NZ_CP030848.1\|WP_149526823.1\|3423602_3424112_-\|redoxin-family-protein	unknown	unknown	gnl\|CDD\|238207
NZ_CP030848.1\|WP_149526827.1\|3430055_3431048_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149526622.1\|3419577_3421026_+\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|377531
NZ_CP030848.1\|WP_149526825.1\|3425244_3427896_+\|peptidase	unknown	unknown	gnl\|CDD\|349459
NZ_CP030848.1\|WP_149526837.1\|3442052_3443024_-\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|237500
NZ_CP030848.1\|WP_149526822.1\|3422837_3423437_+\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
NZ_CP030848.1\|WP_149526835.1\|3440237_3441077_+\|sulfurtransferase	unknown	unknown	gnl\|CDD\|225450
NZ_CP030848.1\|WP_149526829.1\|3432680_3433484_+\|PASTA-domain-containing-protein	unknown	unknown	gnl\|CDD\|225372
NZ_CP030848.1\|WP_149526832.1\|3434942_3435914_+\|YihY-family-inner-membrane-protein	unknown	unknown	gnl\|CDD\|377085
NZ_CP030848.1\|WP_149526836.1\|3441126_3442005_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP030848.1\|WP_149526834.1\|3438213_3440148_+\|30S-ribosomal-protein-S1	unknown	unknown	gnl\|CDD\|235775
NZ_CP030848.1\|WP_149526831.1\|3434531_3434942_+\|YbgC/FadM-family-acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP030848.1\|WP_149526824.1\|3424118_3424982_-\|N-acetylglucosamine-kinase	unknown	unknown	gnl\|CDD\|225518
NZ_CP030848.1\|WP_149526826.1\|3428367_3429360_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149526821.1\|3421489_3422623_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP030848.1\|WP_149526820.1\|3418932_3419427_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149526833.1\|3435955_3438121_+\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP030848.1\|WP_149526830.1\|3433488_3434529_+\|endolytic-transglycosylase-MltG	unknown	unknown	gnl\|CDD\|376862

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526828.1\|3431536_3432541_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	3.21196e-114
NZ_CP030848.1\|WP_149526819.1\|3418501_3418819_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	4.1663e-21
NZ_CP030848.1\|WP_149526827.1\|3430055_3431048_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.76424e-17
NZ_CP030848.1\|WP_149526622.1\|3419577_3421026_+\|IS1182-family-transposase	gnl\|CDD\|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	6.73829e-13
NZ_CP030848.1\|WP_149526825.1\|3425244_3427896_+\|peptidase	gnl\|CDD\|349459	cd06240, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	8.25607e-110
NZ_CP030848.1\|WP_149526837.1\|3442052_3443024_-\|formimidoylglutamase	gnl\|CDD\|237500	PRK13776, PRK13776, formimidoylglutamase; Provisional.	1.70379e-108
NZ_CP030848.1\|WP_149526822.1\|3422837_3423437_+\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	3.94265e-85
NZ_CP030848.1\|WP_149526835.1\|3440237_3441077_+\|sulfurtransferase	gnl\|CDD\|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.21332e-78
NZ_CP030848.1\|WP_149526829.1\|3432680_3433484_+\|PASTA-domain-containing-protein	gnl\|CDD\|225372	COG2815, COG2815, Uncharacterized protein conserved in bacteria [Function unknown].	2.30767e-19
NZ_CP030848.1\|WP_149526832.1\|3434942_3435914_+\|YihY-family-inner-membrane-protein	gnl\|CDD\|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	4.9826e-47
NZ_CP030848.1\|WP_149526836.1\|3441126_3442005_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	6.70645e-71
NZ_CP030848.1\|WP_149526834.1\|3438213_3440148_+\|30S-ribosomal-protein-S1	gnl\|CDD\|235775	PRK06299, rpsA, 30S ribosomal protein S1; Reviewed.	0
NZ_CP030848.1\|WP_149526831.1\|3434531_3434942_+\|YbgC/FadM-family-acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.03636e-39
NZ_CP030848.1\|WP_149526824.1\|3424118_3424982_-\|N-acetylglucosamine-kinase	gnl\|CDD\|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	2.22592e-09
NZ_CP030848.1\|WP_149526826.1\|3428367_3429360_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.61468e-17
NZ_CP030848.1\|WP_149526821.1\|3421489_3422623_-\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	1.91377e-06
NZ_CP030848.1\|WP_149526823.1\|3423602_3424112_-\|redoxin-family-protein	gnl\|CDD\|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	3.55486e-79
NZ_CP030848.1\|WP_149526833.1\|3435955_3438121_+\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.72437e-51
NZ_CP030848.1\|WP_149526830.1\|3433488_3434529_+\|endolytic-transglycosylase-MltG	gnl\|CDD\|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	1.28228e-96

>NZ_CP030848.1|WP_149526827.1|3430055_3431048_+|transposase
MKKDRITLGVDVSKKTLDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLEPSGKLNSTIFDLKQLISFRKRLVREMAGYKASSSERKAMYGKDAGKAILKVSKTMIDVYKKEIYRVEREILQLIESDESLNRNYQILKSVKGIGPVNAWMTIVYTENFKAFTDPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYTQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149526826.1|3428367_3429360_+|transposase
MKKDRITLGVDVSKKTLDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLEPSGKLNSAIFDLKQLISFRKRLVRAMAGYKASSSERKAMYGKDAGKVIQQVSKTMIDVCKKEIYKVEREILQLIESDESLNRNYQILKSVKGIGPINAWMTIVYTENFKAFTDPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYAQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149526825.1|3425244_3427896_+|peptidase
MKHLKASLWLLLLLVGMSVQSRAQQISSPKTHFGFEIGDDYQLANFEQTEKYFKKLSEQSDRVIYQPIGKTEEGREQCMLIISSPENLKDLEKYKQISSQLARAEITEQEARNLSKEGKSVVWIDGGLHSTEVVGMHQLIQTAYLLASATDAETEHILQNSIILLVHANPDGQDLVSNWYMREKEATKRSTSLVPVLYQKYAGHDNNRDFFMLNLKESQNMARQLFVEWVPQIMYNHHQTAPAGAVVAGAPYRDPFNYVFDPLLMSGIDALGAAMSSRLNAENKPGYTAKGGSVFSTWYNGGLRTTTYFHNMIGLLTEIIGNPTPYDIPLVPSRLIPSSNTQNPVLPQRWHFRQSIDYSISLNYAVLGYAARYRDEVLYNIYRMGRNSIEKGNKDTWSLSPSKVAIVEQAVQNARKANPNERFPDANLVNKLYEDKALRDPRAYVIPANQAEFNTAVKFLNALIGNGIEVMKATADFTAAGKSYPEGSYIVKTNQAFRPHILDMFEPQDHPDDFEYPGGPPIPPYDAAGWTLAYIMNVKFDRFLDDISGPFQKLPIGEQIILEKNASAKSKFLSLPAANNDSYQIVNSLLNNKQKVWRDQDNGNFYIANTNNLSLNIPSTAVNAIPKSAKALKTLRIALWDSYGGSMPSGWIRFLMEQFDYNATVVFPPDIDKGNLNDKFDVIILPGGSIPRLQIGAGLGYGPNFNNAAPENIPSPYRERWGRLTAEKSIPVLRDFMEKGGTIVSIGNSFDIAKHFNLGITDALVDADNKPLRREDFYTPGSVLQAKVATNLPDTWGYDEDIDVYYSNSALFKINDQQIKPLIWFDSDQVLKSGWSWGEKYLKDAVLAFDAKIGKGKLVCFGNDITFRAQTHGTFKFLFNQLY
>NZ_CP030848.1|WP_149526824.1|3424118_3424982_-|N-acetylglucosamine-kinase
MILVADSGSSRSDWMLHLPDSKPLQFRTKGLNPFFVNEKEIASVLGQVQEIIPYIKEINEVYFFGAGCTTPDRRELVSNALTEIFPNSFISVESDLVGSAYATFGNNQGLICNIGTGSDISFYNGDTLEQGVHGIGYVLGDEGSGAWFGKQLITAYLYEQMPRDLMRIFKEAHPITKDIIIKNVYQRDRPNAYLASFAEFMAANRTHPYIDNLLRNGFDEFVRTNVMTYPEFWEYECHFVGGIAYHFDLHLREVCNLHGVRIGKILKNPIEEIFHFIVNRELNVEFN
>NZ_CP030848.1|WP_149526823.1|3423602_3424112_-|redoxin-family-protein
MLVKMILLYTMLFQQPSVYDYSFNTIDGKKVSLADFKGKELLIVNTASKCGFTKQYKELQELHKQYGDKLVVIGFPSDNFGGQEFDVNEKIQEFCEQNYGVTFLISEKVDVKGEKAHPLFKYLTSAQNEDFTGDIKWNFEKFLINKDGRLTNRYRSKVTPLDESIVSKI
>NZ_CP030848.1|WP_149526822.1|3422837_3423437_+|thymidine-kinase
MMLFSEHNFHERQERVGSIEVICGSMFSGKTEELIRRLKRAKFAKLPVEIFKPEIDVRYGDKEVVSHDSNAIPSTPVSHSSAILLLSSDTKVVGIDEAQFFDDELPEVCNTLANRGIRVIVAGLDMDFKGRPFGPIPNLMAMAEHVSKVHAVCVQCGSPATYSYRFAENESRVLLGEKESYEPRCRACYFRENKNDEQS
>NZ_CP030848.1|WP_149526821.1|3421489_3422623_-|hypothetical-protein
MAYSQQDIYNKIGDLLVEINEQYASLDKAKLTQDSVQVQLMAAQAKFLAANLDALNQLSAPAIVAAVPELPGTENTVAEEENTFTPAPTFDEHEADSQPVIEEIQEVKSEDVIEETEVVAEAPEEVEEEEQSPEQKTEGIKFEGFGHIDDSVTDNETDQEEAAVVENIEDTVEEEEQEEEVKAVEERPEEPAAPAYTHTASSNYTSVERPTNSFKTQAPVEEKKEEVSNEPVVNEVVIEEKHVEIKEEPKEASLNDLAKQAEQTPSRRMTLNELIQQQKQAGLTNVNQFQTSTSKSSDTIVDLKTGVSLNDKLLFIKDLFNGYSLAYSEAIELLNRFDNFAEADAFLQSNYALKNNWASKPQTVDKLYVVLRKKYVS
>NZ_CP030848.1|WP_149526622.1|3419577_3421026_+|IS1182-family-transposase
MLSTQQKIQFSSYSGLYDIIVPKDNLLRKINDLIDFSFIYDELLAKYCQTNGRTAESPIKMFKYLLLKTIYTVSDVDVVERSRYDMSFKYFLEMAPEEDVINSSSLTKFRKLRLKDMDLLNLLINRTVTIALEKGIIKSKSIIVDATHTVSRSNPHTALAVLRERSKLLRKAIYQIDGEYKRNLPQKNESNDLDQELAYCRELQRVLDEDQSISEIPAVKEKLNLLKETIEDTKEYYLLSKDDEARLGHKSVDSSFFGYKTHLAMTEERIITAAVVTTGEKGDGPELPRLLEISQQNGMQVDTIIGDAAYSGKENLQVAKEQNIDIIAKLNPSITQGFRKDKDKFDYNKDADMFVCPAGHLAIRKARQGKKEQGTNQTETYYFDVEKCKVCPLREGCYKQGARTKSYSVSIKSELHREQMAFQQTDYYRSKSKQRYKIEAKNSELKNVHGYGRADAYGIHNMEMQGAMAIFTVNLKRILKLI
>NZ_CP030848.1|WP_149526820.1|3418932_3419427_+|hypothetical-protein
MNELTYYTEISEDLQKNNPTAYEELDEEIHIIIHKLKFIPLESRPIVQVISNDESIQQDYLQELLKVAGAQPIASAVPLEDVEILIFIDETNNYLSTLPVELQTLYAESKAVKNNQIYIIQKSAFAKDKAAYIQDIEVLAEIVQSKYFVFGHEGEEWIKFDIRY
>NZ_CP030848.1|WP_149526819.1|3418501_3418819_-|YbaB/EbfC-family-nucleoid-associated-protein
MFDKLFQAQQKAQEIKDRLDHVSVSGEAEGGKIRVIASANKEIKEINIDPEFLKDADKEELEELLIVALNKAITQAESISQAEMAAASQDMLSGLGGLGNLFGNK
>NZ_CP030848.1|WP_149526828.1|3431536_3432541_-|D-alanine--D-alanine-ligase
MKTKVALVKGGYTGEAEVSFKSAAFVYSQIDKDKYDVYPITISLDSWFYEDEQGAKHEIDRQDFSLELAGNKVTFDVAFIIIHGVPGEDGRLQGYFDMIGLPYTSCTALTSALTMNKGYTKAIVQDIPELNVAKSVLLFKEHRPVSVDMVTEKLSLPIFVKPNAGGSSIGMSKVSEWSALKQALDNAYDAENTGYQVLVEEFVNGREFSQGIYRDAKGELQVLPATEVRTTREFFDYEAKYTPGLTEEITPADLNTEQKERADRLIKEIYIRLNCKGMVRIDFFIENNTDKFFFIEINTVPGQTAQSFIPQQVRASGRTETAFYGELIEAAMGE
>NZ_CP030848.1|WP_149526829.1|3432680_3433484_+|PASTA-domain-containing-protein
MSKFFLYLRTSTFRKNLIAALIFIVVLFVVVYFGLKIYTKHGDSQEVPVLKGLHINEALKILDNAGLEYEVDSIYQMDAKPGLVIDQDPDPKSHVKGGRTIYLTIITQSAPEIAFPEIVDKTFIEASAILKNHSLKIADTTYINDIARDVVLEVKFSGQVIQPGRMVPKGSRISLVLGNGRGDSEVDIPNLVGQSVEEAKFALAGLGLTLGSISFSDNSRDTLNARIVSQSPDTSTHVISIGSAVHVTLAMPTAAPATPVNPTTPQN
>NZ_CP030848.1|WP_149526830.1|3433488_3434529_+|endolytic-transglycosylase-MltG
MSENRKKNSALKVILIIILVVGLAVAWIGYRAFIAPSIATSEEYFYVHTDEPYESVIKRIEDEGIVKNPSYFNYVARAMDLQTGIKPGRYKLSKDLSNRRFIGNLRGGYQEAVPFRFQNLRLKENFAGALGKNFEADSTTFLNLLNNEALAEKYGFNKDNFFLMFIPNTYEIYWNTKPEEIIDRFSKEYAKFWNADRKAKAAALNMTPEEVSVLASIVKGEALHVDEMPEIAGLYINRLKRGMLLQADPTVIFANNDFTIRRVLNRHLTIDNPYNTYRYKGLPPGPIMMPSIASIDAVLNYNQHEYIYMCAKDDFSGYHNFAKTVAEHQVNARKFQQALDARNIKK
>NZ_CP030848.1|WP_149526831.1|3434531_3434942_+|YbgC/FadM-family-acyl-CoA-thioesterase
MFSYKHQVRVRYAETDNMGYVYYGNYAAYYEVARTEMLRSTGISYKELEDMGVMLPVIELHCQYIKAAKYDDLITINIYIREKPGIRIKFEYELFNEEGELLNTGSTQLVFVDMERNRPCRPPAIFQEKMAPFFGE
>NZ_CP030848.1|WP_149526832.1|3434942_3435914_+|YihY-family-inner-membrane-protein
MKKVHQTLLHLQPYDRLIEWSKSATLPGFGKLPLYTVFVFFFQEISRESIINKASSLAYNFMLAIFPGIIFLFTLIPYIPIDNFQEQLMDLIQLALPDNAYQVLENTLKDIIIRQNGGLLSAGFVLCTFFATNGMTTLMMTFNKSSLSKESRTWFQRRIVALVLSFSIVFALICGIVLYMGSNFLINYLKTHIDYDLSWFWSFLIKTAQWLILFSIYFFTVSLIYKFGPSSSRWKLFTPGATLATLLAMLSFSLFTFYINNFGAYNKLYGSIGTLIVVMIWMYMNALILIIGYELNASIALSKQSIKIVKPRVYNSFKANQAE
>NZ_CP030848.1|WP_149526833.1|3435955_3438121_+|response-regulator
MQQEDKYLVDRTKRNKSIRNILLLSTIGLFVAFLIFFISSFIQYRSIQSRIERIYSSINTDQTSFVTLLTKFNDAENHFRQYSLNYDSTDFLEYNKNLMLLRASVDSLRKVREVEEIVDQKYRSDSIDYSRLLPMYIDLAANIDSLMQSARTLDEFHRTAINNSMFNLPQENSIANSDLSRSTPSVIINRKPLLQRIFQPKPDTLTLGSDLLSQDTRNMLHQSFSRIRSESDARAQGKLDEIKLQLTDLRQKERLMLADNFTLLHKTNQQIRFVYDQRIKFQREKSDQELNVLLANTDTFKWQIIVSLTFVFIVICILVYYQFFTNYYEQMLMDEKIYASKLAEQKTDILAEITHEIRTPINSMIGIVDLLRSRNDLYQPKDILLLETAYSNITATSKTINDILNLSKIDKHDTIEPNHFDFHDMLLEILDNYRNQASLKKITLNHSLDESKPTIIFTDELKVRQVVSNLVSNAIKYSSQGTVTTKMYVNNHSNLVIKVSDEGNGIPENLKKNIFKKYYTENKTNKVEGGVGLGLYITKNIVTLLKGKISFQSRANQGTTFTVEIPIPRPKFRRKNTLNIHQVRDLPKNLSWLIVDDNALNLLYLKQFFLLHEQVYTATNGLEALNLMETKAVDVIVTDINMPVMTGDELLVKVRQNPAYERVKIIATSSDNEQVKKQEGIRRMKFDGILIKPFNEKKLTEVILKTLYPIFEDSDEIQQEG
>NZ_CP030848.1|WP_149526834.1|3438213_3440148_+|30S-ribosomal-protein-S1
MAKKQEAEKELAAKNAELQGADTKVVKDTEKIESEADSNLIDEIKSNTWSTPSGDFDWDLDEKAFGNYSEAERVKLEEQYAGTFNQINQGEIIEGIVVSINNKDVVLNIGFKSDGLVALSEFRDLPDLKVGDTVDVFVESQEDANGQLVLSRKRAKTQKSWEEINAALENDAIIDGFVKSRTKGGLIVDIKGVEAFLPGSQIDIKPIRDYDVYVGKTMEFKVVKINHEFKNVVVSHKVLIEDDLENQKSEIVAKLEKGQVLEGTVKNITDFGVFIDLGGVDGLLHITDISWGRIEHPKEVLALDQTINVVVLDFDDEKKRIALGLKQLSEHPWESLDTGLEIGSKVKGKIVTVADYGAFLEIIPGVEGLIHVSEMSWSQNLRSPQEFLKVGDEIEAVILTLDREERKMSLGIKQLTPDPWQNITERYPVGSKQSAVVKNMTNFGVFVELEDGIDGLIHISDLSWSKKVNHPNEFTKVGERLDVVVLELDEENRKLSLGHKQLEENPWDTFETIFTEGSVHEGTVIKVGDKGDIVALQYGVEGFCPNKHSVKEDGSSLKVDEVAEFKIIEFNKENKRLVISHSRIWEDAKAEARIEEFNARKKEAKAASSAVRKVKDNVEKSTLGDLDVLAQLKEQMEDNEKKSK
>NZ_CP030848.1|WP_149526835.1|3440237_3441077_+|sulfurtransferase
MNRALIDIEQVQNFIKEHADRVIILDASIDKVGQKLDNNNLELIPNSHFFDIENAFSDKAINLPHTMVDASTFENEARKLGINEDSIILLYDRWGVYSSPRAWWMFKYMGFDQVYVINGGLPAWKSADLPTVDSYAAVEQTGNFIAKPNSEWIIKIDELKELVGEADVHITDARSAGRFSGAAPEPRPGLKSGHIPGSKNIPFDQVLDGAYFRSNEQIAPLYADKSFSSGQNIFTCGSGITASILALGAYELGYPHIRVYDGSWSEWGSDPDTIVDQNI
>NZ_CP030848.1|WP_149526836.1|3441126_3442005_-|pirin-family-protein
MSNIDFIREETAADIGNFLVGRLLPFRQKRSIGPFVFIDHMGPACLADHENLDVGLHPHIGLSTLTYLFEGSIFHRDSLGTAMEIKPGAVNWMTAGKGVVHSERTPEYLRQKDKFLHGLQIWVALPKELEFQEPEFHHVEADAIPAWEADGVSYKLIAGEAFGKKSPVPVHSKLYMIEIKTTKDALIDIRGELYGESGLYILEGEIESNGYTYGPKQILITLDAHLCSFEMKAGTTVYIFGGEPFPEERFIYWNFVATSKEIIEEAKQKWINHEFPKVPGDDGYVPLPAARK
>NZ_CP030848.1|WP_149526837.1|3442052_3443024_-|formimidoylglutamase
MAILDNAYYQPGDQQNWQGRIDGTEQAFLRWHQVVDAIDLSKQQSLDGAFVILGFCCEEGVRRNQGRIGAKEGPAAFRKVLAGLPVHFSNTTRLIDAGDVICANEKLEEAQGCLHAAVNKIISMGGFPVLLGGGHEITYPHYLGLQTATKQSVGIINIDAHLDIRPLIAGKGNSGTGFYQIAQHVEKENLPFHYLAIGIQEISNTKALFDYADAKGVEIIQAKDIYTERLGEIIDQIIDFGKKVDQVYLTIDLDAFAASYAPGVSALAFNGIVPDHNFHLLFETIIQLSNLVSIDIAELNPLFDIDNRTTKLGADLLFKLLQK

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Crispr_ID: NZ_CP030848_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_21

3640485-3640568

Orphan

Consensus_repeat	Method
TGGTTCAGACAAAAGGCATTCCTTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_21

>merge|NZ_CP030848|21|3640485-3640568|CRISPRCasFinder
TGGTTCAGACAAAAGGCATTCCTTGCCTATCCTGTTAATCCTTGCATCCTTCCTTTCATGGTTCAGACAAAAGGCATTTCTTGC

>NZ_CP030848|21|21|3640485-3640568|CRISPRCasFinder
TGGTTCAGACAAAAGGCATTCCTTGC	CTATCCTGTTAATCCTTGCATCCTTCCTTTCA
TGGTTCAGACAAAAGGCATTTCTTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149526971.1\|3641996_3642989_+\|transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP030848.1\|WP_149526962.1\|3623078_3624806_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|366183
NZ_CP030848.1\|WP_149526966.1\|3634277_3634643_-\|transposase	unknown	unknown	gnl\|CDD\|379669
NZ_CP030848.1\|WP_149526965.1\|3629852_3632873_-\|DUF2723-domain-containing-protein	unknown	unknown	gnl\|CDD\|378545
NZ_CP030848.1\|WP_149526972.1\|3643147_3643870_-\|iron-sulfur-cluster-repair-di-iron-protein	unknown	unknown	gnl\|CDD\|274701
NZ_CP030848.1\|WP_149526976.1\|3647882_3650015_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|320700
NZ_CP030848.1\|WP_149527752.1\|3624818_3627923_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|188247
NZ_CP030848.1\|WP_149526975.1\|3647225_3647789_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP030848.1\|WP_149526973.1\|3643871_3646112_-\|nitric-oxide-reductase-large-subunit	unknown	unknown	gnl\|CDD\|225795
NZ_CP030848.1\|WP_149526969.1\|3639321_3640278_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP030848.1\|WP_149526979.1\|3652208_3652664_-\|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|275036
NZ_CP030848.1\|WP_149526968.1\|3635546_3638714_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|379297
NZ_CP030848.1\|WP_149526978.1\|3650682_3651969_+\|citrate-synthase	unknown	unknown	gnl\|CDD\|99867
NZ_CP030848.1\|WP_149526964.1\|3629115_3629661_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	unknown	unknown	gnl\|CDD\|235365
NZ_CP030848.1\|WP_149526977.1\|3650019_3650382_-\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NZ_CP030848.1\|WP_149526970.1\|3640745_3641342_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP030848.1\|WP_149526967.1\|3634704_3635391_+\|phospholipase	unknown	unknown	gnl\|CDD\|226584
NZ_CP030848.1\|WP_149526974.1\|3646185_3646734_-\|azurin	unknown	unknown	gnl\|CDD\|259989
NZ_CP030848.1\|WP_149525778.1\|3633313_3634267_-\|transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP030848.1\|WP_149526963.1\|3628148_3629087_-\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149526971.1\|3641996_3642989_+\|transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.75202e-17
NZ_CP030848.1\|WP_149526962.1\|3623078_3624806_-\|TonB-dependent-receptor	gnl\|CDD\|366183	pfam00593, TonB_dep_Rec, TonB dependent receptor. This model now only covers the conserved part of the barrel structure.	4.62116e-05
NZ_CP030848.1\|WP_149526966.1\|3634277_3634643_-\|transposase	gnl\|CDD\|379669	pfam14690, zf-ISL3, zinc-finger of transposase IS204/IS1001/IS1096/IS1165.	0.00173034
NZ_CP030848.1\|WP_149526965.1\|3629852_3632873_-\|DUF2723-domain-containing-protein	gnl\|CDD\|378545	pfam11028, DUF2723, Protein of unknown function (DUF2723). This family is conserved in bacteria. The function is not known.	2.53255e-83
NZ_CP030848.1\|WP_149526972.1\|3643147_3643870_-\|iron-sulfur-cluster-repair-di-iron-protein	gnl\|CDD\|274701	TIGR03652, FeS_repair_RIC, iron-sulfur cluster repair di-iron protein. Members of this protein family, designated variously as YftE, NorA, DrnN, and NipC, are di-iron proteins involved in the repair of iron-sulfur clusters. Previously assigned names reflect pleiotropic effects of damage from NO or other oxidative stress when this protein is mutated. The suggested name now is RIC, for Repair of Iron Centers. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.96107e-83
NZ_CP030848.1\|WP_149526976.1\|3647882_3650015_-\|hypothetical-protein	gnl\|CDD\|320700	cd07341, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	2.21432e-24
NZ_CP030848.1\|WP_149527752.1\|3624818_3627923_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|188247	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF. Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.	2.2437e-13
NZ_CP030848.1\|WP_149526975.1\|3647225_3647789_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	1.3897e-89
NZ_CP030848.1\|WP_149526973.1\|3643871_3646112_-\|nitric-oxide-reductase-large-subunit	gnl\|CDD\|225795	COG3256, NorB, Nitric oxide reductase large subunit [Inorganic ion transport and metabolism].	0
NZ_CP030848.1\|WP_149526969.1\|3639321_3640278_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP030848.1\|WP_149526979.1\|3652208_3652664_-\|T9SS-type-A-sorting-domain-containing-protein	gnl\|CDD\|275036	TIGR04183, hypothetical_protein, Por secretion system C-terminal sorting domain. Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.	4.04801e-05
NZ_CP030848.1\|WP_149526968.1\|3635546_3638714_+\|TonB-dependent-receptor	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	8.38898e-16
NZ_CP030848.1\|WP_149526978.1\|3650682_3651969_+\|citrate-synthase	gnl\|CDD\|99867	cd06114, EcCS_like, Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS reaction is thought to proceed through three partial reactions and involves both closed and open conformational forms of the enzyme: a) the carbanion or equivalent is generated from AcCoA by base abstraction of a proton, b) the nucleophilic attack of this carbanion on OAA to generate citryl-CoA, and c) the hydrolysis of citryl-CoA to produce citrate and CoA. There are two types of CSs: type I CS and type II CSs. Type I CSs are found in eukarya, gram-positive bacteria, archaea, and in some gram-negative bacteria and are homodimers with both subunits participating in the active site. Type II CSs are unique to gram-negative bacteria and are homohexamers of identical subunits (approximated as a trimer of dimers). Some type II CSs including EcCS are strongly and specifically inhibited by NADH through an allosteric mechanism. Included in this group is an NADH-insensitive type II Acetobacter acetii CS which has retained many of the residues used by EcCS for NADH binding.	0
NZ_CP030848.1\|WP_149526964.1\|3629115_3629661_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	gnl\|CDD\|235365	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR.	3.51438e-63
NZ_CP030848.1\|WP_149526977.1\|3650019_3650382_-\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	4.01514e-27
NZ_CP030848.1\|WP_149526970.1\|3640745_3641342_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	5.46459e-61
NZ_CP030848.1\|WP_149526967.1\|3634704_3635391_+\|phospholipase	gnl\|CDD\|226584	COG4099, COG4099, Predicted peptidase [General function prediction only].	1.37018e-20
NZ_CP030848.1\|WP_149526974.1\|3646185_3646734_-\|azurin	gnl\|CDD\|259989	cd13922, Azurin, Azurin is a redox partner for enzymes such as nitrite reductase or arsenite oxidase. Azurin is a bacterial blue copper-binding protein. It serves as a redox partner to enzymes such as nitrite reductase or arsenite oxidase. The copper of Azurin is tetrahedrally coordinated by a cysteine, 2 histidines, and a methionine residue. The electron transfer reactions are carried out with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. Azurin can function as a tumor suppressor; it forms a complex with p53 that triggers apoptosis in various human cancer cells.	3.01101e-58
NZ_CP030848.1\|WP_149525778.1\|3633313_3634267_-\|transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.16411e-59
NZ_CP030848.1\|WP_149526963.1\|3628148_3629087_-\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	0

>NZ_CP030848.1|WP_149526969.1|3639321_3640278_+|ribose-phosphate-diphosphokinase
MPLQFNTVKLFAGSGTLELADKISKAYGKPLGDKTLSKFSDGEIQPFYNESVRGSDVFLIQSTNQPTDNLLELLLMIDAAKRASAHYITAVVPYFGFARQDRKDKPRVAIGAKMIANLITAAGASRIMTMDLHAAQIQGFFDIPVDHLDGAIIFVPYIKSLNLENLMIASPDMGGSYRARTFAKFFNAEVVICDKRRKRANEIESMSIIGDVTGQDVVLIDDICDTAGTLSKAAALIMENGARSVRAVCTHAVLSGKAYETIENSVLSEMIVTDTIQLNPEKAATCSKIRVLSTDKLFANAIKNVNEHGSISDLFNVD
>NZ_CP030848.1|WP_149526968.1|3635546_3638714_+|TonB-dependent-receptor
MLRKLSGIVAVLLINLLLCNSNLFAQSTDATITGKVMDANGPVKGTSITIHNESTGFKQTTLTNQNGVFTFLQLPLGSPYSVSANHIGYTGQKKSGYKLSYGDELVIDFELADQSNEIDEIVINGGDLKDKIKTLGASTAITANELKKMPVNGRNFSSLIDLSPVSNGNNLAGQRASSTNFTVDGMNSRSTVAGGNASGAYAISMEAIQEFKVVTNDYDVTYGRSGGGSVTTVTKAGTNTFKGSVFTFGRTDWLSSQYNLNGTPRSQEFSTYQTGFSLGGPIVKDKAHFFVALDRQRDARPLQIANIVSPEDVARYKVTQATLDEFAQIAEQKYGANPDRLFGEFNKKKNTDAAFARIDWQINDKNLLTIRNNFIYDMDDQQEGDNSNINAYESYTNRKYITNSLMASLRTSINPKITNDFKLQYFLERSEALHNVEGFGQDQSIPRAIVEEVESIDGNDKYYRSIQIGGQRFAPEWFHGDMFQLVNNVYYNTEKIKYTFGIDAMYTDMNFRYGSEMNGRYYFTGMKNFADLKPYRYARDVYMTDQENTKVNNLAIGIYGQLETKVARGLDMVLGVRLDNTQYLRKANFNQVVYDELGISTDNGINTFQFQPRVQFTWDVNEERKDIIRFGAGIFGSALNPYSMLNNVLFDGTKIAGVDITDPALIPTPNFPGYRNDPNSAPGRDLLNQPGVEKLITINTNHKDVKVPTVYKANFSINHFFSPSLRIGLSAYATWARNNYMYVDRNMVDEPYFRLAAEGNRGVYIPADKINANNGAANWVHSRKTDQIGRVLEMNSEGKNNTYTVVVDGTYRYWKDGQVSMSYTWNDAKDNTSYNGNVANSATLSLMVQDDPRDLSRMTYSDNQFRHKVVFYGTLPSIWGISMGLRYSGIAGTRYSLSVKGNVNGDFVASNDLAFVYNPDDNNVPQNLREGIQKILDNPKAEQSIKDYIRNNAGRIAERNGGVNGFYGVFDLHLAKEFKFYKTHGIEASVDIFNVANLFNKDWGVGNNLGKQELYSIKSFDAQKLQYLYNMTSNVGVSTLNGNPFQVQLGLRYSF
>NZ_CP030848.1|WP_149526967.1|3634704_3635391_+|phospholipase
MTQDFKKGIFTIETDTIPYRFLEPKETFLKKRYPLVIAFHNSSRIGNDNEKQLEHLTKTWLKPDIRATYPCYVLAPQFNERSSNYSKSEEGFLESRPSQQAKLVLSLIKELQKRYPNIDDNKIYLIGYSMGASTAQNLMAMAPKEFRALVSIAAVPDLSNLNAFKRKPTLLIHGQMDLENPYEGSVAQFERLKGNKRLILKTYDYLNHATITIPFLSGDEIPKWLFKH
>NZ_CP030848.1|WP_149526966.1|3634277_3634643_-|transposase
MHESFNALMPLIIPEGVSDYFEMTHYSKEEKRLDIFLEELNNRPEEYQGQKLISKGFFEPVTLQDFPIRGMQVYLHVKRRRWLNQDTDKVVYRNWELVAKGTRITQDFAAFLKGISGQPGS
>NZ_CP030848.1|WP_149525778.1|3633313_3634267_-|transposase
MSSFYGISASKLRRYYRNKLSGFQDWEHRENARDGLIFPQNVSGHLSIDETCLSHGELYTVVTNKEARGKKGTIVAILNGTKSENIIPILQKIPQRLRNKVQEITLDLAGNMGLIAKRCFPNAVQVIDRFHVQQLATEALQEIRIKHRWQAIDDENQAIDQARKNKETYFPEVLSNSETIKQLLARSRYLLYKSEHKWTYEQRERAAVLFERYPDIEKAYRLSQELSWIFNTTIDKIYAFTRLAKWADKVEQAGFKSFNTVSRTINIHHKKILNYFDNKSTNASAESFNAKIKAFRSQFRGVGDINFFLFRLTKLFA
>NZ_CP030848.1|WP_149526965.1|3629852_3632873_-|DUF2723-domain-containing-protein
MNYTKLNNLLGWACGIIATLVYVLTAEKTTSWWDTGEFIASAYKMQIVHQPGAPLFLMIQNVFSNLAMGDRTQIAYWMNIGSAVCSGMTILFLFWTITALARKAYVKFSRTAEVSQTALINIMGAGVVGALAYTFTDTFWFSAVESEVYAMSSLCTAVVFWAILKWEVRADEPGSDKWLLLIAYVMGLSIGVHLLNLLVIPAIALVVYFRRAQTVTSAGVLKALAIGVVVLGLVLWGIIQYLIKFAAYTDLFFVNTLGLGFGTGVTFFALLVVGGLLFGLWYSIKHVKPILNIALLSVSFIIFGYSSFSMILIRAKANPTLNNSDPDNAFTFLSYLNREQYGDEPLLSGRYFDAKPTDIFETGNVYRKDGNKYVVAKKKYDYTFDHTTLFPRVYSDKHEGFYRDWLSMGAGDKPSMGNNLNFFFTYQIGHMYSRYFMWNFVGRQNDQQGHGSFTEGNWISGIKPLDNIRLGGQDVLPTSEKENAGRNTYFFLPLILGVLGALWQFKKQNRDAAVVALLFFFTGLAIVLYLNQTPMQPRERDYAYVGSFYAFSIWIGLGVIWIAEKLSGKINAKNAAIGATAVSFLAGPVLLASQNWDDHDRSEKFLARDMAKNYLESCAPNAILFSYGDNDTYPLWYVQEVENFRPDVRVVNLSLLSADWYMKQMMHKVNEADALPINIDPEKIKDGVRDVIYYNDFNVPENIEIKTLLDIMLSDNQQNMVQLQSGEYANVLPTKKMQYTVDKAAVIANKVVPKEWEDAIVDTMKWNYSMNIVSRAELSLLSILANNNWKRPIYFTTTTPDENMIGLNKYMVSEGFALRLMPVALAADSASNNEPISDVEGTYNNIVNKFQWGNIANSKYLDPDSYRYISMYVGSLFGETAQNLLAMGKTTEAKKLVNNAYENMPKRVYQMAEVFSYASLIDAMYKVGEKDKANEITKRNLQYLRENMAYYTAIAEKKPNLEYRNMRFGLASIQNYQRVLTEANQKELLDEVNKIFEVYRPLFEGN
>NZ_CP030848.1|WP_149526964.1|3629115_3629661_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR
MKQSILLDGPKFQITLKRLSQQLIENHGDFSNAVIIGIQPRGTYLAERLIQEIKEMTGVEVPLGILDITFYRDDFRMKGQSPLLANSTHIDFIVDDKDVIFVDDVLWTGRTIRSAMDAIQAFGRAKRIELMVLVDRRFSRQIPIQPDYIGIQVDSIDSQKVIVSWKEVDDSDSIVLITEKK
>NZ_CP030848.1|WP_149526963.1|3628148_3629087_-|aspartate-carbamoyltransferase-catalytic-subunit
MSTSEQLSTRHLLGIKDLNSNDIQLILDTAANFKDVLNRPIKKVPSLRDITIANVFFENSTRTRLSFELAEKRLSADIINFAASSSSVSKGETLIDTVNNILAMKVDMIVMRHPYAGAGVFLSRHVDAQIVNAGDGAHEHPTQALLDSFSIRERLGDVAGKKVAIIGDILHSRVALSNILCLQKQGAEVMVCGPTTLIPKYIRSLGVKVEHDLIKALNWCDVANMLRIQLERQDIAYFPSLREYSMLYGLNKEILDSLDKEIVIMHPGPINRGVEITSDVADSSHSIILDQVENGVAVRMAVLYLLAGQRGS
>NZ_CP030848.1|WP_149527752.1|3624818_3627923_-|tetratricopeptide-repeat-protein
MYHKAKVFDTCFYNWKAYKKGVIDRMYKKIYQVGVALTLLSTPVFAQHSAWQEVNKAYKEGLELYERGKYSSAAKQFDKVEEIRTKSTLQLDETEELSLLKENVRFFQAVCALELGESDAENRFLKYIRDYPASANSKAAYFQIGKSYYAKQDYAKAIEWFEKIDSKNLAGAENTEYRFKLAYAKFMTGDYEASKPVFTELKDKSGQYQEASIYYYAYLSYLDQEYKTALNEFERLEGSKTYENSYPYYITALYFLDKRYDDVLAYALPKLQSTKQESETEMFRIVAATYFIKGDLVKSKEYYDKFQAQDQGKTQNNQDSYQIGYINYKLGNYEKAIQELEKLEEPDAYFQSAMITLGDSFLKTGNKQSARNAFFRASKLDFDPQLKEEGLFNYAKLSYDLEFHQVALDAVQEYIKTYPRSKRNEEAKTLLAEVLLSTKNYRAAVDVLEDLDRRSKEANAAYQKVTYYRGLEYYNERAFENAISMFMRSEASRHDEEIYALATYWKAEAMYEVRKYKEAVANFNKFLQLPAARKTDVYNYANYALAYAAFRADNYSTAANYFERFLSGGGKDGIDLNTRNDAMARAADSYLAIKNYSKAANYYDRLIASGAQSQDYALFQKGILLGLQGNNQGKIETLNSVMSKYPKSNYADDVAFEVPYTYFLMGQHDLAITGLQKMVEQYPRSSYVPRALTTIGLVQYNKDDNDAALATFQRVVNQYPTTDEAKQALASIENIYLDKGDASGYIRYATSTNIGDLSTAEQDAHAFSVARTLFDRGNHQATVEAVNAYFDKFPKPIQEKHARFLRAESNAALGKDKEAMHDFNIIMNDWTSAYTERTLVSVAKLHLRNKAYNEAVQVLKKLELTSEYKENYGWAVNNLLVSYFNIGDYTETLTYANIIKKYEKASEEDIAKAHLYAAKAYLSTSKGSEGMKELNLAALKSKTETGAEARYLVAEQQVKNKNYDGAIKSAMDISDSFSSYDYWVAKGFILMAKAYIGKDDKFQAKSTLESIIDNYENTTDGVLDEAKKLLATIK
>NZ_CP030848.1|WP_149526962.1|3623078_3624806_-|TonB-dependent-receptor
MKLNTIVKQSGLLALLLAMGSQAYAQRDTTNRPVTLDSFDIVRDYRPILADAVKIRRSPDMANKREYMPKLNYGNVPDKKLDINTGLSELKIMETPFSRIVDHSSNYVKLGVGNLGTILGEAYFAVEDYEDIRFGGFVKHLNQKGNLDDQKFSRQEVGVFGRRIFPMFTVNGLIGYNGFGTRFYGIPMDVDNNNLNPTREAQRFNDIYFSGELTSNFDPANEDALSYSVKADAYTYRDKFEGKENSIALSGYLNKRLRTFNIGANVALDFNSIGGVNTPDGNLNNSLVNANPYIKFKGDNYNITLGANIVSEFGDSSRFNIFPVAEIDFSLVPGYFYIFGGVKGGVEKGSFRSFTKTNPYLGLTPNIMNTVERMNIYGGIKGNAGATFGYKVKAFYRQIEGLPMFVNNVDRPFQFDLVYDGDGDKALKHVGIEGEINVRLSELVNLGGRLNIDNYTTVSQEEAWHLPKMRLAANARFNISEKLYIDAEALFHGNATAREYTYTTDQATNVTSPSATYSKTSIPSFFDLSAGAEYKATKQLGIFVKANNIFNTEYSRYLYYPKLGFNILGGINFSF
>NZ_CP030848.1|WP_149526970.1|3640745_3641342_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MKSIAISGSARQNVGKRDSRELRYEGQIPAVLYGGKEQTHLSVSAADLKSVLYTPEVIFVELDINGKKTKAIVQDAQFHPLTDLVTHVDFLELFDDKEVSINIPVKLTGTSPGVKMGGKLVQKLRSLRVKALPNNLPQEVEVPMEGLEVGKSFRVGQVKLENAVVLNNADDTIVSVIMSRALRQAEQEAAKAAKGGKK
>NZ_CP030848.1|WP_149526971.1|3641996_3642989_+|transposase
MKKDRITLGVDVSKKTMDICHWGTHDFIKIENNSSGFKQLAKWMRGKGFVSSQVFFIMEYTGGYEYRFLQYCESKGLSYTRKSGLEIKKSMGMVRGKSDKQDSFRIAQYGEEKAYMLEPSGKLNSTIFDLKQLISFRKRLVRAMAGYKASSSERKAMYGKDAGKVILKVSKTMIDVYKKEIYRVEREILQLIESDESLNRNYQILKSVKGIGPVNAWMTIVYTENFKAFTDPRKYAVYAGVIPFEHTSGTSIRGRKRVSHMANKAIKQELNQAAKIAITHDKTLREYAQRKLTTKAYPLVLNNVKFKLILIMFSLIGRQEMYREDYHYAA
>NZ_CP030848.1|WP_149526972.1|3643147_3643870_-|iron-sulfur-cluster-repair-di-iron-protein
MENLVNEKIGDIVAKNFHAAAVFSKYGLDFCCGGGKSVQEAAAKKSVDVEKLTEELKTVLSEPNETHIDYASWPADLLASYIEKTHHRYVREKAPVILAYLNKLCQVHGGRHPELLEVNKLFQECAKELGQHLVKEEKILFPYIVQMINSEIDHTQLAAAPFGSIENPIHLMEHEHDAEGERFEKIAKLTDNYAVPADGCSTYRVTYEMLKEFEDDLHKHIHLENNILFPKSIALQQALN
>NZ_CP030848.1|WP_149526973.1|3643871_3646112_-|nitric-oxide-reductase-large-subunit
MSRERKLWWSFILVVAISFSVLLYYGYEIYQVSPPVPEQVVDADGKVLFTGQEIKDGQNVWQSIGGQEVGTIWGHGAYVAPDWTADWLHREALIMLDSYAQQEFASAYADLSDEDQAKLQTRLKNNIRKNTFNEETNTLTIDADRVKAVNELSAYYAGLFTDDPQFDQLRKDYAIPKNSIKDPERLHKLNAFFFWATWATVTERPGDQVSYTHNWPNEKLVGNEMTMDLLAWSGVSIILLIFCVGALVLWQVKSGEDDELLYPAQDPLLRQGITPSMRLTKKYFWIVSLLMLVQVGLGIVTAHYGVEGDGLYGIPLDQFLPYSVTRTWHTQLAIFWIATAWLATGLYIAPAVGGKDPKFQCFGVNFLFIALLIIVVGSMVGQWFGVMQKLDLVQNFWFGHQGYEYVDLGRFWQLFLFVGLFVWLALMVRPLIPVLKKGGEEKNLIIMFLISCSAIALFYGAGLMWGRQTNLAIAEYWRWWVVHLWVEGFFEVFATVVMAFLFVRLGLLKPKSATASVLFSTIIFLSGGILGTFHHLYFSGTPTAVMALGATFSALEVVPLTIIGFEAYHNYKLSKSTKWLQDYKWPIYYLISVAFWNFLGAGVFGFIINPPIALYYVQGLNTTPLHGHTALFGVYGMLGIGLMLFVLRSLYRDVQWNEKILKIGFWSLNIGLLAMALLSLLPVGVWQAIASIKEGMWYARSAELMQQPGMVFLKWMRTPGDVIFAIGVFACAWFVFDLTLKNKIKN
>NZ_CP030848.1|WP_149526974.1|3646185_3646734_-|azurin
MKTVNTFGILALSFGLFAASCGNSSQSNNETVDHSAHQTETPATSEAPAPATEPAGSAAASNEVVIESNDQMKYNLSEINVNAAEPVKLTLKHVGTMKKDVMGHNVVVLKAGADVAAFTTAAMNAKDTDYIPESKDVIAHTKVIGGGEQDAIEFTLPGPGTYDFICSFPGHAGIMKGKIIAQ
>NZ_CP030848.1|WP_149526975.1|3647225_3647789_+|aminoacyl-tRNA-hydrolase
MNFLIVGLGNIGKEYADTRHNIGFMVADELANQAGTTWSTLKHAYYTEYKQRGHNVYVIKPTTFMNLSGKAVNYWMQELKVPVQNILVIVDDLAIPFGSLRVKPKGSAAGHNGLRSIEASIGGQQYPRLRFGIGDNFSKGRQVDYVLGPFDKEEQRELPALIEHSVKMVNSFINIGIELTMTNLNTK
>NZ_CP030848.1|WP_149526976.1|3647882_3650015_-|hypothetical-protein
MESLLTYLLQVNLLIIIIFLGYQLLLKGLTFYMLNRVYFLVATLYAFIYPFLDIKSWFAKRVELPIGEVFNYIPFVFEEKASYFSLSDLLLMIASVGAIAFFTKLLIQLFSLLRIHLHSEPSAWREYLFRNVIFPIAPFSFFNKIYVHKEQHLEKELHDIFKHEHVHVEGHHTWDVLLFEIVLVSCWYNPFVWLMRKAVRQNLEYLTDQQVLDKGVDRQTYQYSLLHVTKQGASVGISNQFNFKTLKKRIMMMNKKRSSKLELSKYAFLLPVFILAGATFTLNKAEAKIETVVIKAAETNVSEIGHKLSENIIQQDTTKKKASTQQTEEVVVTGFHSNNANVKELSGLTFSAEQSDTLKGKINNVKVVRGFKARSFDQLIDQGTNKDKIIVIDGKVMPKDFDLSLIDDRRVDNVEILTGKDALAIDPKAKDGIISITTRKEGDPVSRVWRIEKNSMSPTKNDLRLTGRGVSVLGLSHEGKNMSYEIDGKKVSEEDVKKIKHEDIHSIDMKLETGKTEDGKEKKTNLIKVFTKSYAKEHNLPMQDSLKGRLSGVRIRSNSNGENRKLTFRSNAEKGKIVWVVNEKVVESEEADKLDPNNIFSVDVLKGKTTTATYGDDVEGVIKIITKDSPLAVNRPKTNQDVTISTSAKDLPNNAIYFIDDKQATKKEVDNLKSEKIKTVKVIKGDKAVKDYGDKGKNGVILITTRKAKD
>NZ_CP030848.1|WP_149526977.1|3650019_3650382_-|BlaI/MecI/CopY-family-transcriptional-regulator
MEKLTIQEEEAMLSIWQLGGGFIRDILDNLKSDDMPYTTLASTIRNLEKKGYVKAVKYANAKRYEPLITSEEYKAKFMNSFVGDYFKNSYKEMVSFFVKEEKLSPNELEEIMDMIRNNKS
>NZ_CP030848.1|WP_149526978.1|3650682_3651969_+|citrate-synthase
MSETASINLNGSSYEFPVITGTENEKAIDISKLRDQSGYITLDPGYKNTGATKSAITFLDGEKGILHYRGYAIEELAEKSTFLEVAYLLIYGELPSKDVLEKFRADIRAQMMIHEDMKNFFTGFPSKSHPMGQLSCLVGVLSSFYPESLNPNQSDEEEDKMIINLLAKMPTIVSWIQKKSLGHPVVYPKNNFGYIENFLNMIFGEVNQEKTFDPLVIEAMHKLLILHADHEQNCSTSTVRIVGSSNANMYASISAGINALWGPLHGGANQAVIEMLEAIKEDGGDAEKYLAKAKDKNDPFRLMGFGHRVYKNFDPRAKIIKKACDDVLEKLGVNDPVLDIAKKLEEAALNDQYFIDRKLYPNVDFYSGIIYRALGFNSDMFTVLFALGRLPGWIAQWKEMRDNKEPIGRPRQVYTGETLRPYVSIKDR
>NZ_CP030848.1|WP_149526979.1|3652208_3652664_-|T9SS-type-A-sorting-domain-containing-protein
MKFEWSKIARISIMNTLVLWMFIGFAQANTFQADTTKASASKQSLISAKNRNANRVAVIAEESDKLINNVKVYYNPIADQVTVNFKLSKNSHVSIKVMDALGNEVLALHNGDLDAGTQNLNFDSSAKLKEGIYFVRVMSGSETVVKRISVR

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Crispr_ID: NZ_CP030848_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_22

3688872-3688978

Orphan

Consensus_repeat	Method
AAGGATGCAAGGATGGGCAGGATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_22

>merge|NZ_CP030848|22|3688872-3688978|CRISPRCasFinder
AAGGATGCAAGGATGGGCAGGATCGGGTCTAATGTCTCATATCTAATATCTAGTGTCTAGTGTCTAGTCTGAACCAGGAAAAAAAGGATGCAAGGATGGGCAGGATC

>NZ_CP030848|22|22|3688872-3688978|CRISPRCasFinder
AAGGATGCAAGGATGGGCAGGATC	GGGTCTAATGTCTCATATCTAATATCTAGTGTCTAGTGTCTAGTCTGAACCAGGAAAAA
AAGGATGCAAGGATGGGCAGGATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149527003.1\|3687337_3688651_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP030848.1\|WP_149527005.1\|3690814_3691492_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP030848.1\|WP_149526995.1\|3678031_3678475_-\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
NZ_CP030848.1\|WP_149527012.1\|3707314_3707980_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP030848.1\|WP_149527011.1\|3704770_3707155_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NZ_CP030848.1\|WP_149527008.1\|3698907_3699321_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527010.1\|3702146_3704543_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NZ_CP030848.1\|WP_149526994.1\|3677310_3678009_-\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
NZ_CP030848.1\|WP_149527007.1\|3695704_3698155_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NZ_CP030848.1\|WP_149527009.1\|3699635_3702020_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NZ_CP030848.1\|WP_149526620.1\|3694757_3695666_+\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527002.1\|3685965_3687321_-\|response-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP030848.1\|WP_149526997.1\|3679953_3680499_-\|transcription-termination/antitermination-factor-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_CP030848.1\|WP_149527000.1\|3683070_3684240_+\|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|366466
NZ_CP030848.1\|WP_149526998.1\|3680519_3680714_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|376355
NZ_CP030848.1\|WP_149527006.1\|3691955_3694304_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NZ_CP030848.1\|WP_149527004.1\|3689473_3690727_+\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP030848.1\|WP_149527001.1\|3684643_3685963_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|227333
NZ_CP030848.1\|WP_149526996.1\|3678765_3679764_-\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|119365
NZ_CP030848.1\|WP_149526999.1\|3681053_3682241_-\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|183708

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149527003.1\|3687337_3688651_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	2.17801e-42
NZ_CP030848.1\|WP_149527005.1\|3690814_3691492_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.33456e-114
NZ_CP030848.1\|WP_149526995.1\|3678031_3678475_-\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	6.06606e-91
NZ_CP030848.1\|WP_149527012.1\|3707314_3707980_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	4.83159e-97
NZ_CP030848.1\|WP_149527011.1\|3704770_3707155_+\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	5.57026e-45
NZ_CP030848.1\|WP_149527010.1\|3702146_3704543_+\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	1.03708e-47
NZ_CP030848.1\|WP_149526994.1\|3677310_3678009_-\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	1.38362e-135
NZ_CP030848.1\|WP_149527007.1\|3695704_3698155_+\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	1.26161e-38
NZ_CP030848.1\|WP_149527009.1\|3699635_3702020_+\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	1.40297e-42
NZ_CP030848.1\|WP_149527002.1\|3685965_3687321_-\|response-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.20943e-150
NZ_CP030848.1\|WP_149526997.1\|3679953_3680499_-\|transcription-termination/antitermination-factor-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	1.74678e-61
NZ_CP030848.1\|WP_149527000.1\|3683070_3684240_+\|BamA/TamA-family-outer-membrane-protein	gnl\|CDD\|366466	pfam01103, Bac_surface_Ag, Surface antigen. This entry includes the following surface antigens; D15 antigen from H.influenzae, OMA87 from P.multocida, OMP85 from N.meningitidis and N.gonorrhoeae. The family also includes a number of eukaryotic proteins that are members of the UPF0140 family. There also appears to be a relationship to pfam03865 (personal obs: C Yeats). In eukaryotes, it appears that these proteins are not surface antigens; S. cerevisiae YNL026W (SAM50) is an essential component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The protein was localized to the mitochondria.	9.87663e-14
NZ_CP030848.1\|WP_149526998.1\|3680519_3680714_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	1.31163e-09
NZ_CP030848.1\|WP_149527006.1\|3691955_3694304_+\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	2.10812e-55
NZ_CP030848.1\|WP_149527004.1\|3689473_3690727_+\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.1461e-25
NZ_CP030848.1\|WP_149527001.1\|3684643_3685963_-\|GHKL-domain-containing-protein	gnl\|CDD\|227333	COG5000, NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms].	1.07804e-33
NZ_CP030848.1\|WP_149526996.1\|3678765_3679764_-\|glycoside-hydrolase	gnl\|CDD\|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	1.96599e-91
NZ_CP030848.1\|WP_149526999.1\|3681053_3682241_-\|elongation-factor-Tu	gnl\|CDD\|183708	PRK12735, PRK12735, elongation factor Tu; Reviewed.	0

>NZ_CP030848.1|WP_149527003.1|3687337_3688651_-|TolC-family-protein
MKYLTIYLYIVTICCCLVSNLKGQTRTLSLSDCIRMAVANNPTLLRSELNIDRADLQYKQARYDRLPEVSGGLAHELSQGRSIDPTTNQYVDRYNSYGNQYLNANVPIFNGFAILHNIRRRANAKEAGKLEFEGARNELKLDVIEAYLKVLTAQDMLTQIEGQIAVTKEQLHRHEVLNREGAVAPGDLYDIKGQYNSDLNLLEQTKQSLNDAKLTLATFLNINIAELPALEKLETEQASTAYSADDLFRSSLTVLPEYRALDWRMKEMEQHIKLMKSEYYPSLSFGAGLGSNYSKDGGEAFNQMKNNLRKSLSLSLTIPIFNRFATRTNVRLAQVDFNEAVLNKSIRENELRMNTAKAVFDLRTAQTHVQNLKEQEQSYQEAFRIANVHFEAGNSNSVIYLTAKNKLDNTRSQLVIKQYEWLLQKYINDYYAGALNL
>NZ_CP030848.1|WP_149527002.1|3685965_3687321_-|response-regulator
MKKATVLVVDDDQDLLTATRILLRPKVKEVIVEHNPEKLLNILEKHSVDILLLDMNFKSAINTGNEGLYWLGKVKENFPAVQVVMITAYGAVDLAVKSLKQGAADFIVKPWQNEQLLSTLQGLMDEHKPAQANVKSKPMVSDQGIVGKSAIMNDLFYKLDKVSPTEANILILGENGTGKDLIANAIHQRSLRNKNPFIKVDVGSLTETLFESELFGYKKGAFTDAREDRKGRFENADSGTLFLDEVGNINLQQQAKLLSVLQNRAVVPLGSSQPVAVDMRLISATNVPLKALADESRFRKDLIYRINTLEIQVPALRERTDDIPLLANHFLDFYNRKYHKNIAGLEADALHKLKQYHFPGNVRELQYSIERAVIMSDQSSLRAEDILFSPIESVPEATSSSTDFSSHNLEEMERKAIKSAIERYNGNISKAAKELGLTRAALYRRLEKYNL
>NZ_CP030848.1|WP_149527001.1|3684643_3685963_-|GHKL-domain-containing-protein
MSRLAIADFFKVLALLSLAVGIAYLIFLGYYSYALLLFLITFYLAYRFVASHRFLVKQMLEFSEAVKYRDFTRRFVVKNNQSTEGKLYQAFNQINEIYKNISIDQALQHQYLNKVINMLDTAILFFHADTGKVIWVNDAFKSLFQVPHLGNIAGLQRRNADLYEKTMQLKVGKQQMETTNSASGKIKVLLQCSEFETQDGQFRIVVYQNINEAIDETETKAWHKLLRVLTHEIMNSIGPISSLAETLHSRLEQWEGDQDIEDLKVGIFTIKRRSEGLLQFAKSYRLINKVDQPQVAEILLVQLFENIYQLLEPTLLQKNIDVDIIIKNTRMVLLADINLVEQVLINLLLNAIEAVKDQEDPYISLSGIESNGRIQIKIQDNGVGMSPEIQEQIFTPFFTTKKTGTGVGLTLSKQIMLMHNGNLLVDSQEGEGSVFTLQF
>NZ_CP030848.1|WP_149527000.1|3683070_3684240_+|BamA/TamA-family-outer-membrane-protein
MFNTRLFKILPLAALTLGLHLNATAQETSPDSTNFIKKIIKKFVSSEKDSTRSASFMVLPAVGYAQETGFEYGIASTYNFYIDKQDLNSRTSNLTLIGTLTTKKQKNIKLISDIWTKGNEYHILSELRYRDWPFNFYGIGNDTWKADEDYLDQKLYRIKLDGEKRFAPNFYAGLNVNYEHLKFKDMEAGGIFEEPTVYGKSGGQYLAIGASALYDNRNNTTYTTRGFYGRAKYSYAPNFFGKDNFIGSQVEVDVRGFYPINNTLTIAAQGLFRGTYGDNVPFYVLRDLGGDMTMRGYYLGRYKDNNYATAQAEIRYRFHPRIGINGFLGTGSTFSKENDIRLLPSYGAGLRYFFSLEHNSSIRFDYAFGEQRPGEKRQSGFYLSISEAF
>NZ_CP030848.1|WP_149526999.1|3681053_3682241_-|elongation-factor-Tu
MAKEKFDRSKPHLNIGTIGHVDHGKTTTTAAITKVLADKGLSEVRSFDSIDSAPEEKERGITINTSHVEYQTANRHYAHVDCPGHADYVKNMVTGAAQMDGAIIVVAATDGPMPQTREHILLARQVGVPALVVFLNKVDLVDDTELLDLVEMEVRELLSFYEFPGDDIPVIKGSALGALNGEEKWVDSIMELMDAVDNYIPIPPRLTDLPFLMPIEDVFSITGRGTVATGRIERGVINSGDPVEILGMGAENLKSTVTGVEMFRKILDYGEAGDNVGLLLRGIEKTDIRRGMVICKPGSVTPHTDFKAEVYVLSKAEGGRHTPFFNKYRPQFYFRTTDVTGEITLEAGTEMVMPGDNVTITVKLINAIAMEKGLRFAIREGGRTVGAGQVTEILA
>NZ_CP030848.1|WP_149526998.1|3680519_3680714_-|preprotein-translocase-subunit-SecE
MAKVLDFIKDSYTEITEKVTWPTWSQLQSHAVVVLVASLIIAIVILIMDKASSNVMELLYGTGA
>NZ_CP030848.1|WP_149526997.1|3679953_3680499_-|transcription-termination/antitermination-factor-NusG
MADQSLKWYVVRAVSGKEKKVKQYLEAEINRLGIQHLVTQVLIPMEKYYQMRDGKKVAKERNYYPGYVLIEAALDGEIEHAIKNVNSVIGFLGDKAGNAIPLRPSEVNRILGKVDEMAEQGESINVPYYVGETVKVSDGPFNGFTGEIEEVHEDKKKLTVMVKVFGRKTPLELNYMQVEKE
>NZ_CP030848.1|WP_149526996.1|3678765_3679764_-|glycoside-hydrolase
MQIYRTILVTFFVCASLLLHAQQKPFIISYVTAGTKALPDPNLITHINYAFGQVNKTFNGVVISNESRLREVVAMKKKSPHLKVLLSIGGWGSGRFSEMAATAENREAFAKDCQRIVQAFDLDGIDLDWEYPSSSESGISSSPDDVDNFTQLMRDIRKTIGKKKLLTLATIADAKYIDFKGIDPYIDFVNVMMYDVTLPPFLHNSLYRSERSGRVTLVEAMEAHMNAGVKKEKLVMGIPFYGRGDKKETPDYVMFKDYAKLAGFEEKWDDVAKVPYLLNEDGTLVFTFENVESLKLKAAYIKSQGLLGAMYWEFYGDDEQLSMSKALFESLN
>NZ_CP030848.1|WP_149526995.1|3678031_3678475_-|50S-ribosomal-protein-L11
MAKEVSALVKLQVKGGAANPSPPVGPALGAKGVNIMDFCKQFNARTQDKPGQVLPVVITVYADKSFDFIIKTPPVAVQLKDAAKLKSGSGEPNRKKVASITWDQVKTIAEDKMPDLNAFTVESAMKMVAGTARSMGITVSGDAPWKN
>NZ_CP030848.1|WP_149526994.1|3677310_3678009_-|50S-ribosomal-protein-L1
MARLTKNQKAALSKIEAGKAYSLKEAAALVKEITTAKFDASVDIDVRLGVDPRKANQMVRGIATLPHGTGKTVRVLVLCTPDKEEEAKAAGADFVGLDDYISKIEGGWTDVDIIITMPSVMAKVGKLGRILGPRNLMPNPKTGTVTTEVGKAVTEVKGGKIDFKVDKTGIIHTSVGKVSFDADKIYDNALEVLQTISRLKPSAAKGTYFKSIHISSTMSPGIHVETKSVAGI
>NZ_CP030848.1|WP_149527004.1|3689473_3690727_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MDRPIKQKTWNTKRLLTVGGVVALVGLIGASYYFTSGNSKLNVEAERIAIFEVKEDTFQEFIPINGTVLPISSIYLDASVGGRVEEKYVEDGAHLRKGDPIMRLSNTDLELSLINQETQVLNLLTQAQIAQTSAQQATINNRNQMADVEQALKEAERVYTLNKKLLAEKAIGSQEYQKSLNEYNYQKERIGLTNQIVRQDEVSNAQKLNQDRETYKRTQSALQLMRQKVGDLILRAPVDGQLTSFDAEIGQNKTAGERLGQIDVLTGFKVRAEIDEHYINRIFPDLKGQFSIDDKSYELRIKKVYTQVKDGRFLVDMEFIGARPESIRRGQTLPIRLALSDKTKAVLLAKGGFNQQTGGNWIFKLDKSGNTAYRTDIQLGRQNPEYYEVLGGLKPGDKVVISSYETYDKIQELSIKQ
>NZ_CP030848.1|WP_149527005.1|3690814_3691492_+|ATP-binding-cassette-domain-containing-protein
MIKITNLQKFYRTEEVETVALNDVNIHVKEGEFVAVMGPSGCGKSTLLNIVGLLDDLDEGSYLFNSIEVAKFKENKRSDLRKHNIGFVFQSFNLIDELTVFENVELPLVYTNVPAAERKKRVEEVLEKVQIMHRRNHFPQQLSGGQQQRVAVARAVVNNPKLILADEPTGNLDSSNGNEVMQLLTELNEAGTTIVMVTHSEYDAKFADRVIRMLDGQVILEDVRN
>NZ_CP030848.1|WP_149527006.1|3691955_3694304_+|FtsX-like-permease-family-protein
MFKIAFRNLKKNKGFTAINIIGLAIGMAAAILIILWIRSEVTFDRQYSNLDRTYVVGNKAIWGDKIQVWFWTPRVMARTLETEFPEIEHAVRVEGGGNDLLSVGENKLNKETGIFADEHFFDIFDFEVLAGDTKTALSNVNSIVLTESLAKKLFNSTDVVGKFVQRNNEEQFAVSAVLKDLPANSTYNRTSYLLPMKYHDSKNPGDTQWNNNTLQTYILLKEGANVELLSKNIKGLVQRHTETNADNLIKPLADMHLYDKYENGVVAGGRIDTVRVFLVIACFILLIACINFMNLSTAQSEKRAKEVGIRKVVGAGKSSLIKQFLSESILLAIFAGLAALLIVIVALPSYSKLVDRALTLPYDSIAFWIAFMAFTIFTGLVAGSYPAFFLSSFKPIRVLKGKFVFKVNSFSTRKVLVVSQFIIAIVLIVSTITIRKQIQHAQDREVGYNKERLIFLYENGDVEKNFKSIKQELLEQGIASSVTRTMSPITLRWSNSNGFEWAGKSKDNTVIFNRTAADDKLIETTGLELVKGRDFDLSKFPTDSAAAIINESAAKEIGFADPIGQIIKDGSQSYQIIGVIKDFIQESPYDPIAPLIIEGAHGYLATTHIKFQPNIHTREALDKTEAILKKYNPLYPFEYTFVDEDYAKKFNESEKTGQLASLFAGLTIFISCLGLFGLSAFMAENRTKEIGIRKVLGASVFSVTRMLSKEFVLLVIIACIVAFPLAYWAMNSYLSTYAYRISVSWEIFLITAITAILIAIFTVSYQSIKAAIANPVNSLRDE
>NZ_CP030848.1|WP_149526620.1|3694757_3695666_+|transposase
MINQAKALKLIKLYQYVCDKYDSELQYYCQRFSNNNKPDFTDQEVLTIYLFSVHEEQRLRIKQIHKFASDYLMDWFPKLTSYVAFNTRINRLFDVLRSLCQSVIEDFTPEECSREFSLLDSMPIITCSGTRRAKVALEITDKSFCSTKRLWYFGLKLHALNSYNKSTLPRPESIVISKASESDLNIFKENWASIAGRTFFGDKIYRDAPFFEWFYKEKKSIMYTPIRETQGKPDCLKNRDRAYNDLFSRAVSKVRQPIESFFNWINEKTQIQNASKVRSTKGLLVHVFGKLTACFIKPIFNP
>NZ_CP030848.1|WP_149527007.1|3695704_3698155_+|FtsX-like-permease-family-protein
MFNSLRHLKRNKLFSFLNILGLTIGISSCWLIYRFVSYELSYEQGIPDKENIYRVLSNFKRDGQDELFGGLSRPIYFHMKQEMDGLENVVPSFRMFVAKIDIPAIAGQDAKQEEPDYLETAVINTVPSYFDMLPYKWLAGDKRTALNDPFQLVLTEKRAKYYFPTLSPQEIVGKTIVYNDSLKKTVSGIVENLPFPSEFIGQEFLLLKERAEDKRLASWTNSNGADKVYILVKDKAAADKALTEIQATVKSKWEEFKAETKPTYEYTRSINFMPIKDSHFASHMNERDADKTSLQVIYGLIGVGIFLLLLACINYINLTTAQLPQRYKEIGIRKTLGGSNKSLVLQMMTETAIIVGLATVLSAFVVQIAMLFLGDLLSEGAKTNSNPLLFIVFIAFVLLTTSVLAGFYPSWIISKVNAVDIFRNKGTVAVGQNRINLRKALIVFQFIIAQIFIVGALIVGQQLKYLVEKDMGFNKDAVILSEIPYKLFEDPNFETKKITLSNELRQIPGVEAVTMGTAPLSPDYSSSHMNYYPKGQLEPISQNIFTKVIDQEYFSFYDLKLTAGAPLLPSDTTNGYIINETAARGYGFKNPQDAIGEIIGQKGYEQRIVGVMKDFHTRDFYSNIEPLALLHSKEQLGDYGIRLSSTNRKEWPQIIEQVKSTWAKFFPEDTFTYKFYDESILAMYKKEQNLYKLTNISTGIAIIISCLGLFGLATITAFQRSKEIGIRKVLGATVSGIVGMLSKDFVKMVILAILIASPIIWWACNKWLQDFVYRIELSWIPFVLGGLFALVAALLTVSYQAIKAAKTNPVDSLRDE
>NZ_CP030848.1|WP_149527008.1|3698907_3699321_-|hypothetical-protein
MKSTIKLAVLALLAVSTTAHSSCSKDEEAGPSIDVATGSFKGTLKSRLPGKAFNTTANAIVTVSKQNGSEMKITMPFPEGAYTRVIKVASLDGDIMSEDPQDPAGIFIYYTATSQLSISSQPLAADAVQFSFQGPKQ
>NZ_CP030848.1|WP_149527009.1|3699635_3702020_+|FtsX-like-permease-family-protein
MIRNYFNILARSLAKNKVFSFINIIGLSIGMAAAILITLWIQREYSMDKFHEKSDRLYVVYNRDTDGIETWVNNNTQKILTTTLQSDYPEVEGATIYNGSSNLFRIGDKKIKGYGAVVDSVFLNMFSFPLLEGDANTALADPSHIVLTASFVKTLFGNENPVGKTLTVDSASQFTVTAVLQDLPNNTKFGFKYLIPRSYAKRINPDQDGWGAFSTTSYVLLKEGASQTALENKIKNLAKDNTKSAGLPITAEPFLHPIDKKYLYNKDVNGQLVAGEISKIRLFTAIAGFILLIACINFMNLSTAKSEKRAKEVGIRKVVGVTKMGLILQFIFESVFLSFVSFLIALGLVYLALPHYSQLVGGKLIVPIQEPGFWLLSIAFILFTGLLAGSYPAFFLSSFNPVKVLKGTFKSARSTVSARKVLVVIQFTFAITLIISTIIIYNQIRYALDRDAGYDREQLIAVPMEGKIRSNYDLIKNEILNTGAVSSMTKSLSPITQKWSDQWGLEWDGSTKQDEQTVFVKFGTDADFAKTMGLKIVEGRDIDVNKFPTDTSAILLNEAAIKAMRIKDPIGKLINHVGYKEANYKIVGIVNDFVFGSPFVDKIEPMMICGPRAYYATTIHMKLSDKFETKESLSKIEQVLKKLNPDYEFVYDFTDEDYAYKVASAERTGKLVTLFAGLTILISCLGLFGLAAYMAENRTKEIGIRKVLGASVLQVTSLLSKEFIVLIFIAFLIASPIAWYAMKNWLSDYSYRTEISWWVFAITGGLAVIITMLTISWQSIKAAIANPVSSMRDE
>NZ_CP030848.1|WP_149527010.1|3702146_3704543_+|FtsX-like-permease-family-protein
MLKIAFRTILKTKSLTFVQIFGFSIAIATATILFLTAMFELSFDKFHKDIDRIGVVYIETNTANGTNYNTSVAAPLAPLMKKELPNVEEVSRLLNGNILLRNGDKELRSNNKYVDQSFFSMFDFELIAGNKTALDNLDGLVIDENTATALFGTTDVVGKTVEFNQTGTWENNVVTAVTKSVPANSSIQFNSLTRFEKSPQYQERMNEWTHKDHTLLVKVKSSKLDDRKFADATRSFAQVHYNDEITKLKRDGAKPDEHGAYINIHLLPLSDLHLTSVEYGSIEKTPFPWILLLISGLILFIAGSNFVNLSLANSLSRIKEIGTRKTIGGTTFQLFKQLWLESFIICVIGLILGILFATLLLPEYNATLGYHFKIAQLFDPVNIAVFLTAFLILTLITGGYPALRMARANIIQSLKGTGKIKSTPMQNSLTVLQFAIAIILCIATIVISFQLHYLTNRPLGFNKSEVVSIPIGNSIDGQQALERMRIELAAHPWAKSVSGSDINLGRGRDNSTSTSRFGFDHEGKEIITNFLRIDYDYLKTLDIKLIAGRDFNKSFGTDTNAVLINKEMALAVGGEDAILGKPLGMDGSPTVIGIVDNFNFQDLKQQVGPLTMSVNPNIFPVQYIFVRVETNDLAKTLEDVESIWKKVNPRSNIDASYLDENTQNLYKNDRRFGKIVITGASVAIVISCLGLFALTVLLINGKIKEIGIRKVLGSSISNIILLLSKNFIKLISIAFLIAAPIAWIAMNKWLQSFAFRIEIEWWMPALAGLIALAFAMLTIAWQTYKAARVNPVDSLRDE
>NZ_CP030848.1|WP_149527011.1|3704770_3707155_+|FtsX-like-permease-family-protein
MYLKTAFRNIRKNRGFSLINILGFSLGITCFLLLAGYIYHEANYDRFLGNSERIALVSAAFKSGESNEFQQSSVTPTAVAPLLMREFPEVEKAVRVYQYNDAALVRKGNDWLKESKLKFVDREFLEVFDYPVIAGDANTPLVNPNAIILTKDLADKYFQNADPIGKTLRIDDTDRIVTAVIDNPPTYSEVQFSGLLSNVGLERYKKEDWGAANDVTFILLKDPSQLSALEKKFNTRIGEMFKEAFTNGFSIKMNMESLPRLHLHSKAAGSGQIVYIYVFACLALALLLISCINFMNLSLAQAPERAKEIGVKKVLGARKDTIFKQFLFEGSLMVFISLVIGFVLAYLLFPFFAKYLGSEMQLQVWKEPLFFVAIIVFFITLSLLASGWPAWLIAQYRPIKALKAKLSTRSSKFNIGNVLITIQYTVSIFLVICTFFAYKQMQFLQNTDTGLNRERIVVLDGDVWSQQERETMKTMLLGKNTIKSVSASYDSPVDIQGGYTITEAEGKANDFSLSITAIPIEKDFLSVFEIPVLAGETLTDADILKARDTSDNRSVAFVINKLAAQNLGWTPEQAIGKRLVLNGRKGNIKTVVDNFNFASLRDEVKPVVLFPEYNYFGNIFVKIQDQADSRQALAEMETVWKSMKPNSTFEYHFLDDDYAKLYQQEQQTTKIMQLFAFITISIACIGLFALSAYATQKRVKEIGIRKVLGASIGKIVRMLTSDFISLICIAFLIAVPLGFLAMNKWLGNFAYHTNMDWWVFVLAGLMTLFVSFLTIGSHAIKAAKANPVDSLRDE
>NZ_CP030848.1|WP_149527012.1|3707314_3707980_+|ATP-binding-cassette-domain-containing-protein
MIRLENIFKWYNLGSTKSFVLKDINLEIEEGDFISIMGPSGSGKSTLLNVIGMLDEPNEGKYFFMDEDVLAMKAKKRNQLFQSHIGYVFQSYHLIDELTVYENIETPLIYKNMSSSERKAIVSDMLDRFNIVGKKDLFPAQLSGGQQQIVGIARALAGSPKLLLADEPTGNLNSKQGEEIMELFKQLNNDGVTIIQVTHSEKNAEYGKRIIDLLDGQIVKR

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Crispr_ID: NZ_CP030848_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_23

3789688-3789801

Orphan

Consensus_repeat	Method
ATTTTTTCTGAAAGTGTCTGTTTTCAAAGGCCATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_23

>merge|NZ_CP030848|23|3789688-3789801|CRISPRCasFinder
ATTTTTTCTGAAAGTGTCTGTTTTCAAAGGCCATCAAGAACTTTCATCCCTGTTGCTGTTTCAAAGGAAACATGAAAGATTTTTTCTGAAAGTGTCTGCTTTCAAAGGCCATCA

>NZ_CP030848|23|23|3789688-3789801|CRISPRCasFinder
ATTTTTTCTGAAAGTGTCTGTTTTCAAAGGCCATCA	AGAACTTTCATCCCTGTTGCTGTTTCAAAGGAAACATGAAAG
ATTTTTTCTGAAAGTGTCTGCTTTCAAAGGCCATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149527083.1\|3787353_3787761_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|224523
NZ_CP030848.1\|WP_149527082.1\|3785808_3787215_+\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235779
NZ_CP030848.1\|WP_149527094.1\|3800421_3801486_+\|galactose-1-epimerase	unknown	unknown	gnl\|CDD\|185696
NZ_CP030848.1\|WP_149527088.1\|3793983_3794424_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367555
NZ_CP030848.1\|WP_149527080.1\|3783305_3784913_+\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP030848.1\|WP_149527095.1\|3801501_3801762_-\|prevent-host-death-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527079.1\|3782727_3783297_+\|chemotaxis-protein-CheB	unknown	unknown	gnl\|CDD\|319752
NZ_CP030848.1\|WP_149527076.1\|3777318_3778446_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527087.1\|3791084_3793928_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP030848.1\|WP_149527078.1\|3781893_3782727_+\|protein-glutamate-O-methyltransferase-CheR	unknown	unknown	gnl\|CDD\|224271
NZ_CP030848.1\|WP_149527084.1\|3787757_3788054_-\|DUF3817-domain-containing-protein	unknown	unknown	gnl\|CDD\|378962
NZ_CP030848.1\|WP_149527089.1\|3794442_3795423_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527093.1\|3799840_3800314_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527085.1\|3788244_3789633_+\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235798
NZ_CP030848.1\|WP_149527077.1\|3778456_3781906_+\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP030848.1\|WP_149527090.1\|3795505_3796156_-\|alpha/beta-hydrolase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527081.1\|3784995_3785538_+\|azurin	unknown	unknown	gnl\|CDD\|259989
NZ_CP030848.1\|WP_149527091.1\|3796174_3798286_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP030848.1\|WP_149527086.1\|3789885_3790932_-\|DUF2157-domain-containing-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527092.1\|3798444_3799791_-\|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl\|CDD\|234897

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149527083.1\|3787353_3787761_+\|acyl-CoA-thioesterase	gnl\|CDD\|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	1.47323e-32
NZ_CP030848.1\|WP_149527082.1\|3785808_3787215_+\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235779	PRK06327, PRK06327, dihydrolipoamide dehydrogenase; Validated.	0
NZ_CP030848.1\|WP_149527080.1\|3783305_3784913_+\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.63488e-80
NZ_CP030848.1\|WP_149527079.1\|3782727_3783297_+\|chemotaxis-protein-CheB	gnl\|CDD\|319752	cd16433, CheB, Chemotaxis response regulator protein-glutamate methylesterase, CheB. This family contains the methylesterase CheB (EC 3.1.1.61; also known as CheB methylesterase, chemotaxis-specific methylesterase, methyl-accepting chemotaxis protein methyl-esterase, or protein methyl-esterase) domain, a phosphorylation-activated response regulator involved in reversible modification of bacterial chemotaxis receptors. Signaling output of the chemotaxis receptors is modulated by CheB and methyltransferase CheR by controlling the level of receptor methylation. cheR and cheB have a strong preference to occur in the same operon, and a subgroup contains multidomain proteins with CheB-CheR fusions. Reversible methylation of transmembrane chemoreceptors plays an important role in ligand-dependent signaling and cellular adaptation in bacterial chemotaxis. Phosphorylated CheB catalyzes deamidation of specific glutamine residues in the cytoplasmic region of the chemoreceptors and demethylation of specific methyl glutamate residues introduced into the chemoreceptors by CheR.	9.34568e-72
NZ_CP030848.1\|WP_149527087.1\|3791084_3793928_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP030848.1\|WP_149527078.1\|3781893_3782727_+\|protein-glutamate-O-methyltransferase-CheR	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	1.86371e-62
NZ_CP030848.1\|WP_149527084.1\|3787757_3788054_-\|DUF3817-domain-containing-protein	gnl\|CDD\|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	8.41224e-26
NZ_CP030848.1\|WP_149527094.1\|3800421_3801486_+\|galactose-1-epimerase	gnl\|CDD\|185696	cd09019, galactose_mutarotase_like, galactose mutarotase_like. Galactose mutarotase catalyzes the conversion of beta-D-galactose to alpha-D-galactose. Beta-D-galactose is produced by the degradation of lactose, a disaccharide composed of beta-D-glucose and beta-D-galactose. This epimerization reaction is the first step in the four-step Leloir pathway, which converts galactose into metabolically important glucose. This epimerization step is followed by the phosophorylation of alpha-D-galactose by galactokinase, an enzyme which can only act on the alpha anomer. A glutamate and a histidine residue of the galactose mutarotase have been shown to be critical for catalysis, the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. Galactose mutarotase is a member of the aldose-1-epimerase superfamily.	1.04824e-168
NZ_CP030848.1\|WP_149527085.1\|3788244_3789633_+\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP030848.1\|WP_149527077.1\|3778456_3781906_+\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	5.01484e-57
NZ_CP030848.1\|WP_149527088.1\|3793983_3794424_-\|hypothetical-protein	gnl\|CDD\|367555	pfam03544, TonB_C, Gram-negative bacterial TonB protein C-terminal. The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.	1.33285e-05
NZ_CP030848.1\|WP_149527091.1\|3796174_3798286_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP030848.1\|WP_149527081.1\|3784995_3785538_+\|azurin	gnl\|CDD\|259989	cd13922, Azurin, Azurin is a redox partner for enzymes such as nitrite reductase or arsenite oxidase. Azurin is a bacterial blue copper-binding protein. It serves as a redox partner to enzymes such as nitrite reductase or arsenite oxidase. The copper of Azurin is tetrahedrally coordinated by a cysteine, 2 histidines, and a methionine residue. The electron transfer reactions are carried out with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. Azurin can function as a tumor suppressor; it forms a complex with p53 that triggers apoptosis in various human cancer cells.	9.55696e-57
NZ_CP030848.1\|WP_149527092.1\|3798444_3799791_-\|deoxyguanosinetriphosphate-triphosphohydrolase	gnl\|CDD\|234897	PRK01096, PRK01096, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	8.55696e-153

>NZ_CP030848.1|WP_149527085.1|3788244_3789633_+|dihydrolipoyl-dehydrogenase
MNYDIIVIGSGPGGYVAAIRASQLGFKTAIIEREALGGICLNWGCIPTKALLKSAQVFEYLNHAEEYGIKVNGGEADFGAIVKRSRGVADGMSKGIQFLMKKNKIDVIMGTAKIKKGGKIDVKAADGTTKEYTAKHTILATGARSRELPNLPQDGTKIIGYRQAMNLPKQPKSIVVVGSGAIGVEFAYFYNAIGTQVTIVEFMDRIVPVEDEEISKQLEKSLKKAGINILTKSEVTSVDTKGDLSKVHIKTAKGEEVIEAEVVLSAVGITPNIEKLGLEEVGVKTDKGRVLVDDYYKTNIDGVYAIGDIVKGQALAHVASAEGITCVEKIKGLHVDPIDYNNIPGCTYCSPEIASVGFTEKAAKDAGYEVKVGKFPFSASGKASAAGAKDGFVKVIFDAKYGEFLGAHLIGANVTEMIAEVVVARKLETTGHEVLKAVHPHPTMSEAIMEAVADAYGEVIHL
>NZ_CP030848.1|WP_149527084.1|3787757_3788054_-|DUF3817-domain-containing-protein
MLRIFQQVALWEAISTILLFFVAMPLKYFAGIPEAVRVAGSIHGFLVVIFVVLLVACWQTYNWSFGRVVKYFFLSLIPVVSFWVEKDLKREIQAQKAA
>NZ_CP030848.1|WP_149527083.1|3787353_3787761_+|acyl-CoA-thioesterase
MNFYTRKWVKPEDLNPNGSLFGGTLLRWIDEEAVIYAIVQLGNPHVVTKFISEINFVSSAKQGDIIELGIEAINFGNTSLTMRCEVRNKISRKTILSIDKLVFVNLDPQGNPVPHGRTEITYAYMGVDRDVNRRD
>NZ_CP030848.1|WP_149527082.1|3785808_3787215_+|dihydrolipoyl-dehydrogenase
MQYDVIVIGSGPGGYVAAIRCAQLGLKTAVIEKYSTFGGTCLNVGCIPSKALLDSSEHYHNAAHNFDQHGISLSSLKIDMKKMIARKNDVITQNTAGITFLFKKNKIDSFEGVGSFVDKNTIKITKNDGSTEEIKGKNIIIATGSKPTALPFLPVDKSRIITSTEALNLTEVPKHLIVIGGGVIGLELGSVYARLGAKVSVVEYAKSIIATMDGGLGKELQRVLKKNLGMEFFMSHKVTGAVAKGKKVTVTAEDSKGQEVVLEGDYCIVAVGRTAYTEGLGLENIGIKTEERGNKITVNEHMETSVEGVYAIGDVVRGAMLAHKAEDEGIYVAERIVGQKPHIDYNLIPGVVYTWPEVASVGQTEEQLKEAGKKYKSGSFSFKASGRAKASGDTDGFIKVLADADTDEILGVHMIGPRAADMIAEAVVAMEYRASAEDIGRICHAHPTFTEALKEAALAATANRAIHA
>NZ_CP030848.1|WP_149527081.1|3784995_3785538_+|azurin
MKKLILAPALALAIAVSSCGNNAEKKEETTSTESTPTTEAPASTTEETVPGIENVTSSQTWTVEGNDQMQFNINLIRVKAGEPVELTLKNVGSMPKESMGHNFVVLKPGVDIPTFGGEAAAAADSEYIPKSSLTSIVAHTKLLGPGESDKITFTLEKGVYPYLCSFPGHFGIMQGKIVAE
>NZ_CP030848.1|WP_149527080.1|3783305_3784913_+|response-regulator
MKTINILLLDDKEENIISLSALLEDVDHVNLISSTDPNDALKICWKEDISIALVDVQMPKINGFEFVSILKSNPKTSHIMAIMVTAISKEDKYLLQGLESGAVDYLYKPLNPEITVAKVRSFVQQILVQQELKEKNRELELSRQELLKTKEEAVQARKSKEIFLANMSHEIRTPINGIMGIMHMFKSSELTAEQRDWLKRLDNASQSLLLIINDILDLSKIDSGMLKIEFEDFSLLKMIEDIDRIFKIKATHKNLNFEIEVDEGVPQYIRYDSLRLQQIISNFISNSLKFTESGSIILTVNLLEQRANNFLLRFIVKDTGIGIKADSVEKIFMAFEQADDGITKKFGGTGLGLAIVKRLAKLLNGQVGAKSEYGKGSEFYFEGWFEASDHDEQKNETNAPSYNTFPKFSNMRVLVAEDNDLNSFMLAHMLRSWNCEVDIVRNGRLALENVEANHYDLILMDTHMPIMSGFEAIKEIKNHIIPEKHGIPIITISASVLEHEQAAAFQAGADGVIGKPFDPIELYQKIVSVTAKINS
>NZ_CP030848.1|WP_149527079.1|3782727_3783297_+|chemotaxis-protein-CheB
MEELAKNIIVVGGSAGAYEVIVDILDHLPAYFSAAIVVVLHRNSKYETKVESSLSRRLNRKVTSVKDKLPILADNIYFAPPGYHLMVEPDHRFSLDISEPVQFSRPSIDVFFESVADVYKTNTTAFLLSGANTDGANGLKRLAELGATCYVQSPEEAKIDTMPKSGQKVSKNVTTLTNAKIITYFSLLT
>NZ_CP030848.1|WP_149527078.1|3781893_3782727_+|protein-glutamate-O-methyltransferase-CheR
MAKLEDSYELSFTEIEDLIFLLKNISDFDLSGYTRSSLKRRIQRIMGLEQMDIVDLKNALVNVPGFQTYFVEEVTVNVTEMFRDPGFYNKLVNDIIPYLSTFPRIKIWSAGCSTGEEVYSLAILLKEHGLSDRSFIYGTDINSKVLDIAKKGIYPLKKFKEYTENFNAFDSKEHFASYYTARYDAAIINHDLRQNILFSTHNLATDQVFNEFHLITCRNVLIYFDLKLQERVMNLFYESLALFGFLCLGTKETLLRHEVMKNFKVVDKEYNIYQKIK
>NZ_CP030848.1|WP_149527077.1|3778456_3781906_+|response-regulator
MSLDMFKLKSARLQAMVSIIVATLVIIFSYWYFTAKQKEYTGAMKEYMDLAQEKFYLIQDWEVEIQQISKFNSLEHNVDAYSRERARTNINATISKLASTNVLIDTVPHSIAKIQAVSDSILSRSAMKSSNSLNTISNNLSDEQDMISAASNMMTNEIIAKRATKTEQKLKFLETTRSITLALGIVSLLVILYVIYQIMKLSVYLTKTSEAERKLNDEFQRTTDKLEELNWVLQNSAKVYNIVNGNLSEHQIAKNALSIVRDVLEGHAAAIYIRKIDSYELTLKDSYGLDSKQLLSNILIGEGIVGHVAESKLPKVFDITELNQVKLSSGIVSALPAKVIIFPIVFEEYCIGVLEVFGSFSKEREENILNFLTRAGRAIGSAIKSRQDQSLVEDLLAETQHQTEELEAQQEELRITNEELVYKTNLLEASEEELRVQQEELSQANKELNQKAAELEKRNVDLKDAQQVVEQKITEVEQASKYKSEFMANMSHELRTPLNSILILAKLLQDNKQKNLSEDQIKYSSVIYNAGSDLLQLINELLDLAKIESGKVELNNEVIPVAGFAHNIESLFKEIADDKKIDFKVDISEAPAEFVSDEYRLEQVTKNFLSNAFKFTERNGQVSLKISLNQNNLNFAVTDSGIGISAEKQTLIFEAFRQEDGSTSRKYGGTGLGLSISKEIASLLGGRIVLESEPSVGSKFTLIIPYVAPSALSLDESPKTQEEQAPVREIEKPKAHITPKPAEEKPMNNAEVAGEKAILIIEDDINFSEILKSFAEGYGFTALQAYDGETGIQLAKSKLPDAIILDVMLPIADGWEVLRTLKNAEETKHIPIHMMSAASFDKKEFLEDGAIGFMSKPVSEASIESAFENINLNLNKGVKKILLIEDQEFQSDLIKKAFAEQQINVIQAFTVESGLKKLEQEGNFDCIILDIKLPDGSGLEMLDKIKSDKKYEKLPVIINTAYDLSTEQTERIMRHTQSMVLKSSKSNTRLTDEVNLFLNKLTEPTYNPVKNLDKIANKENYGTSNLDGKCVLIADDDMRNVFALTSSLQEYNMQIEIANNGREAVEMVNDPANHIDIVLMDIMMPEMDGYEAIQLIRKEKKNNNLPIIAVTAKAMKGDREKSIDLGASDYVSKPIDIDKLVSLMQVWLS
>NZ_CP030848.1|WP_149527076.1|3777318_3778446_+|hypothetical-protein
MYLKEVVNAADSKQFLELPAIINRANRNYIHPLNSDIESVFDRSKNSYFEKGDLMRWNLYDVKDEVIGRIAAFYHFDDKLGENQGGFGFFECINQQEAANLLFDQAKSWLQEHGLKQMDGPINFGTRDQWWGLLIAGFYPPVYGMFYHPPYYQSLFRQYSFEALFEQYTYRRKISVAFSPAVLHRASRIQQDPNYRFEDISKLSEKEIITSFMEVYNAAWKDFDGVNALSRAEVAQLIAHMRPAMDKKIIWFSYFKQQPIGFFINLPDLNQLLVKFLRNGSLNICQKIRFLYRKTTRKCTTMVGMVFGIHPDYQGRGVESAFIVNFANSVSQLRPPTYQEIQMNWIGSFNRKMIAVVESIGAERYKTHCTYRLTF
>NZ_CP030848.1|WP_149527086.1|3789885_3790932_-|DUF2157-domain-containing-protein
MKKLDVSKNEREIIEDALSHWQSQSLLDDDKVKQLKDNLDDKGFEWGVLARYAFWVALASLIFSVVSLFSDDYLNTLIEKFYDTPNVVFCLVFAGLAVLFYMLGFRNKQKNPEKTFSNETLMLAGSFSTAACIGFLGQILDRTDHYFTILFLLSIIIYGFLSVKLGSKLIWVFTLVALGIWFATETALHSNWGFKFWGMNYPLRFTIFGALLTAFAVFAQDKIKPLAIFRSTSYVIGLLYTMIALWLLSIFGNYSDLEKWSSVRQYEIFYWGLLGIGVSLGLALYGMKAKDNVSRDIGFVFFILNLYTRFVEYLWDNINRTVFFLILAVSFWFVGRWAEKIWKKKDSR
>NZ_CP030848.1|WP_149527087.1|3791084_3793928_+|excinuclease-ABC-subunit-UvrA
MAQHKVVDLGDQSEVEVFGAREHNLKNIDVSFPRNQLVVITGLSGSGKSSLAFDTIYAEGQRRYMETFSAYSRQFLGGMERPDVDKISGLSPVISIEQKTTSKNPRSTVGTITEIYDFLRLFYARVSEAFSYVSGKKMERMSDDEITDRILKEFDGEGIYILAPVVKGRKGHYRELFEQIRKQGYTKVRVDGEILDLVAKMQVDRYKIHDIEIVVDRILVEKDSRKRLYTSIGQALKTAKGIIKIANKENKEQFFSRYLMDAESGISYDEPQPNTFSFNSPYGACPKCDGLGYIFEIDKNIVIPDKSLSIQKGAIVPLGPLRESWNFAVLKAVAKKYDFSLTTPVEKLSDEIIDMLLFGEEEPISLTVSYGSYGAREYKIQFAGIFKMLEEMSGKYSDESPALEDFRTQVVCPSCHGDRLKVESLHFKIDNKNIAELSALDIVALNDWFDGLEERLNERQVVIATEIIKEIRTRLGFLLDVGLNYLTLNRSSKSLSGGEAQRIRLATQIGSQLVNVLYILDEPSIGLHQRDNERLINALKNLRDIGNSVLVVEHDKDMILNADYVIDMGPAAGLYGGRVVAEGTAEDILKADSLTAAYLNGKKEVTVPEKRREGNGHSLSLKGATGHNLKNVDIDIPLGKLVLVTGVSGSGKSSVITNTLYPILNHHFFRAKAKPLPYKKIEGLEHIDKVIEIDQSPIGRTPRSNPSTYTGVFSDIRSLYVQLPESKIRGYKPGRFSFNVKGGRCETCQGAGMKIIEMNFLPDVQVPCETCHGKRYNRETLEVRYRGKSIADVLDMSIDDAVTFFENIPSIYRKIKTLQDVGLGYITLGQSSTTLSGGEAQRVKLATELSKKDTGKTFYILDEPTTGLHFEDVNVLLGVINRLVDRGNSILIIEHNLDVIKAADWVIDMGPEGGKNGGTVLFQGTPEGLIKQKNSETGRFLKLEMKG
>NZ_CP030848.1|WP_149527088.1|3793983_3794424_-|hypothetical-protein
MMRVILAFIGLLFASSAIAQERVDSVKLDTAIVRNVDKVPEFVGGVSAWSSFISRSFDAYDVISRLDSTDYVDFGIRQTAIMEFTVCEDGSICDIRVANKDKISPAFAKEVLRVMKRSPKWHPGLKNDKAVRTRIRQNIVGDFELK
>NZ_CP030848.1|WP_149527089.1|3794442_3795423_-|hypothetical-protein
MATKLYNPFLDFKFDNKTCFLTGETLQSEDEQIQVFPMWMMRAFDLEEKPFKMLDESFSTYKKLQLPCSTRAAAAVAAVDGLVEHAVEKGYEAVRELEQEVLFQWIGKILYGVVFNEIQAGIRHAVMTGEELNFSQALVQKFRNLHAMLQSMVIPMEFEHKNPFTIEVFHVDNAEDTFLYRDEINTLIFSLRMKDFGLIATLQDNGTNAIYHEEALALTKGEKLHPVQFEEIGAKYFYTAYLFNRLPEYTYMEVGDKVFVEPMPLNDWTMKPIFDNWQAKTYGQVLENFWKPWGYTLFEIIKDPENPMSFIKDEEGNFKTVEGLPR
>NZ_CP030848.1|WP_149527090.1|3795505_3796156_-|alpha/beta-hydrolase
MKTIYLFSGLGADYRVFSNLDLSGFQPVHIEWLKPRASESLESYLFRLAEYHQIPKQGALVLGVSFGGLCISELAKYYDFEKMILVSSVKNKFEIPAFIKLARLFSLYKLMPRKPSGMMARKAIHWAFGVKTKEEGGLLDVIIQDTDPDFFKWATDQIMQWESVYNPTNCLHIHGERDRIFPINNVVWDIKIKDGGHFMIYNRGKEISFPIRNFIF
>NZ_CP030848.1|WP_149527091.1|3796174_3798286_-|DNA-topoisomerase-III
MKVVIAEKPSVARDLARVMGAKEVKDGYIAGNGYAFTYAFGHLVQLCTPQAYGFHNWSMKNLPIIPAQFALEVKKVRKDGKQMDDAGALKQLNTIKWLLEQAEEIIVATDAGREGELIFRNIYYYLKSNIPFKRLWISSQTDKAIKEGFANLKEGTEYDSLYMSARSRSESDWLIGINATQALTLAAGNKGLLSLGRVQTPTLAMICSRYLENKDFKPQAFYKIQAGFEKEGIQFKATSNKIDKKDVAEETIAKIQVGSNAKVVNVEAKETKEQPPLLFDLTSLQQDANKKWGYSADQTLSIAQTLYEKKVITYPRTGSRYIGEDVFEKIDELFQHLADTAQESIALISKNLIGAKLNKRSVDDKKVTDHHALLVTDEKPGPMPMDQQNIYNMIAKRMVESFSEVCLKDITTVTIDAAGVELIAKGTVIRQYGWRLSADQIDAPDEDKNTDDQDNENAQLPKLTAEELLEILTLELAERFTKARPIHTEASLLKAMETSGKEIEDDEMRQAMKDCGLGTPATRAATIETLFQRDYIKRDKKKLIPTEKGLAVYFLVKDRSIAKVTLTGKWEQKLEEMRANKVSYDVFMKHIKDYTVKITSELMQLRVAIAHEELKPQQKGKIKCPKCSAGQVQLYDKVAQCDHYARGCDFKIWRTLHGVFLDEKEMKSLLEKGKTSELKGLRNTDGSMVNASLLLENFKAVIG
>NZ_CP030848.1|WP_149527092.1|3798444_3799791_-|deoxyguanosinetriphosphate-triphosphohydrolase
MNWNQLISAKRWGYEHREPSEHFDARSEFQRDYDRLIFSSPFRRLQNKTQVFPLPGVVFVHNRLTHSLEVASVGRSLGRLVYNLLKKKHPNIDQEAPFLQEVGNIISAACLSHDLGNPAFGHSGEAAISTFFTDGKGVKYQEMVSKEQWADLTHFEGNANALRILTHAFNGKDPKGFALTYTSLASIVKYPCAAIDGHVKGSHHRKKYGFFDSEKAAFEQIAAELGIAKDPQNPKGYMRHPLVYLVEAADDICYNIIDLEDAHHLKILAYQEVEDLLLPLCAGEDLRARLDSLADTASKVSLLRAKAINTLINGCAQVFVDREEDFLAGTFDKALMDALNPDIVAHMQKISDISVKRIYNAPTVVQIEIAGFKVMNALLEEFVPAYLKTNKSMFDKKLVAMMPEQFHSEKEDTYSKIRAVLDFVSGMTDVYAVDLYRKIKGISIASLD
>NZ_CP030848.1|WP_149527093.1|3799840_3800314_-|hypothetical-protein
MKPIYTYFITIAILLLLIGFFSVAPDSSFIIEPRVGWVLAVPLKETVFALAFFAVLFSVLYRYTEHLLYSHRWSIMHFICFVCLALNFYTWNALSNRFVMRFEELKENAQQVKQLGEMFMRVEGFYSISFFVLILMQGLYLLNLSVGMIYQKRGDLS
>NZ_CP030848.1|WP_149527094.1|3800421_3801486_+|galactose-1-epimerase
MTVYKLPEKKDFESRIQGKNTHLITLTNRAGMQVALTDYGARLVSALVPDKFGNLIDVVLGFSSINGYLKAQEPYHGATIGRFCNRIANGKFTLNEQEYTLAKNNGNNCLHGGPEGFHNRVWDRQVSFNKVVDFYYTSPDGEEGFPGELKTTVSYELTNENEIVIHFRASTDAPTIINFTNHAFFNLNGEGNGDVLNHEIFINSEEFVPIDENQVPTGEIFPVEGTALDFRQPKKIVDYIDSKEAQLKNAGGFDHTFVNNQPPTIAVASAYSKESGVLLEVFTTEPGIHLYAGNFLADDEGKSGHKYLRYGGLCFEAQHYPDSPNHANFPSVVLQPGKEYQSTIKYKFSIKKEV
>NZ_CP030848.1|WP_149527095.1|3801501_3801762_-|prevent-host-death-protein
MGIVETSSKKFKKNQNEFFELADLGQQIIIKRGKKQAYLLTPVSEEDLSFGQEMSERLRLSEQQFKDGDFVRIKSKNELKAFLERI

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Crispr_ID: NZ_CP030848_24

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030848_24

3836192-3836283

Orphan

Consensus_repeat	Method
CCCTTCTTCCTTTCCACACGATCCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP030848_24

>merge|NZ_CP030848|24|3836192-3836283|CRISPRCasFinder
CCCTTCTTCCTTTCCACACGATCCTGCTTATCCTCGCATCCTTCCTTTCCTGGTTCAAAGACAAAACCCTTCTTCCTTTCCACACGATCCTG

>NZ_CP030848|24|24|3836192-3836283|CRISPRCasFinder
CCCTTCTTCCTTTCCACACGATCCTG	CTTATCCTCGCATCCTTCCTTTCCTGGTTCAAAGACAAAA
CCCTTCTTCCTTTCCACACGATCCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030848.1\|WP_149527118.1\|3827425_3828526_-\|dipeptide-epimerase	unknown	unknown	gnl\|CDD\|239435
NZ_CP030848.1\|WP_094258934.1\|3836392_3836746_+\|transposase	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527117.1\|3826178_3827159_-\|deoxyhypusine-synthase	unknown	unknown	gnl\|CDD\|376661
NZ_CP030848.1\|WP_149527114.1\|3820411_3820897_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227659
NZ_CP030848.1\|WP_149527121.1\|3838244_3839123_+\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CP030848.1\|WP_149527124.1\|3841023_3841806_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293806
NZ_CP030848.1\|WP_149527126.1\|3843651_3844386_+\|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213185
NZ_CP030848.1\|WP_149527123.1\|3840472_3840952_-\|cation:proton-antiporter-regulatory-subunit	unknown	unknown	gnl\|CDD\|223564
NZ_CP030848.1\|WP_149527128.1\|3846877_3847948_+\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|237363
NZ_CP030848.1\|WP_149527758.1\|3822466_3824668_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372475
NZ_CP030848.1\|WP_149527119.1\|3828735_3833235_+\|glutamate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236968
NZ_CP030848.1\|WP_149527122.1\|3839161_3840463_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223551
NZ_CP030848.1\|WP_149527127.1\|3844407_3845919_+\|GH3-auxin-responsive-promoter-family-protein	unknown	unknown	gnl\|CDD\|377019
NZ_CP030848.1\|WP_149527115.1\|3820902_3822228_-\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_CP030848.1\|WP_149527116.1\|3824965_3825535_-\|non-canonical-purine-NTP-diphosphatase	unknown	unknown	gnl\|CDD\|237823
NZ_CP030848.1\|WP_149527113.1\|3820029_3820329_-\|DUF4834-family-protein	unknown	unknown	gnl\|CDD\|374375
NZ_CP030848.1\|WP_149527120.1\|3833253_3834702_+\|glutamate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237213
NZ_CP030848.1\|WP_149527684.1\|3836786_3837722_+\|transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP030848.1\|WP_149527759.1\|3825598_3826102_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030848.1\|WP_149527125.1\|3841921_3843622_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193

Protein	Function_ID	Function_description	E-value
NZ_CP030848.1\|WP_149527118.1\|3827425_3828526_-\|dipeptide-epimerase	gnl\|CDD\|239435	cd03319, L-Ala-DL-Glu_epimerase, L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	2.81882e-109
NZ_CP030848.1\|WP_149527684.1\|3836786_3837722_+\|transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.27678e-60
NZ_CP030848.1\|WP_149527121.1\|3838244_3839123_+\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	1.56176e-150
NZ_CP030848.1\|WP_149527114.1\|3820411_3820897_-\|hypothetical-protein	gnl\|CDD\|227659	COG5361, COG5361, Uncharacterized conserved protein [Function unknown].	0.00152415
NZ_CP030848.1\|WP_149527124.1\|3841023_3841806_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293806	cd07720, OPHC2-like_MBL-fold, Pseudomonas pseudoalcaligenes organophosphorus hydrolase C2, and related proteins; MBL-fold metallo hydrolase domain. Pseudomonas pseudoalcaligenes OPHC2 is a thermostable organophosphorus hydrolase which a broad substrate activity spectrum: it hydrolyzes various phosphotriesters, esters, and a lactone. This subgroup also includes Pseudomonas oleovorans PoOPH which exhibits high lactonase and esterase activities, and latent PTE activity. However, double mutations His250Ile/Ile263Trp switch PoOPH into an efficient and thermostable PTE. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.14269e-29
NZ_CP030848.1\|WP_149527126.1\|3843651_3844386_+\|LPS-export-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213185	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system. The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.	2.3515e-146
NZ_CP030848.1\|WP_149527123.1\|3840472_3840952_-\|cation:proton-antiporter-regulatory-subunit	gnl\|CDD\|223564	COG0490, COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism].	1.46429e-49
NZ_CP030848.1\|WP_149527128.1\|3846877_3847948_+\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	1.28694e-161
NZ_CP030848.1\|WP_149527758.1\|3822466_3824668_+\|hypothetical-protein	gnl\|CDD\|372475	pfam13100, OstA_2, OstA-like protein. This is a family of OstA-like proteins that are related to pfam03968.	3.98509e-27
NZ_CP030848.1\|WP_149527119.1\|3828735_3833235_+\|glutamate-synthase-large-subunit	gnl\|CDD\|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NZ_CP030848.1\|WP_149527122.1\|3839161_3840463_-\|cation:proton-antiporter	gnl\|CDD\|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	2.4811e-52
NZ_CP030848.1\|WP_149527127.1\|3844407_3845919_+\|GH3-auxin-responsive-promoter-family-protein	gnl\|CDD\|377019	pfam03321, GH3, GH3 auxin-responsive promoter.	1.555e-158
NZ_CP030848.1\|WP_149527115.1\|3820902_3822228_-\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	4.65501e-59
NZ_CP030848.1\|WP_149527116.1\|3824965_3825535_-\|non-canonical-purine-NTP-diphosphatase	gnl\|CDD\|237823	PRK14823, PRK14823, putative deoxyribonucleoside-triphosphatase; Provisional.	1.71177e-98
NZ_CP030848.1\|WP_149527113.1\|3820029_3820329_-\|DUF4834-family-protein	gnl\|CDD\|374375	pfam16118, DUF4834, Domain of unknown function (DUF4834). This family consists of uncharacterized proteins around 90 residues in length and is mainly found in various Parabacteroides and Bacteroides species. Protein in this family are characterized by a strongly conserved KDEGEYVD motif on the C-terminal and a very divergent N-terminal. The function of this family is unknown.	2.69854e-05
NZ_CP030848.1\|WP_149527120.1\|3833253_3834702_+\|glutamate-synthase-small-subunit	gnl\|CDD\|237213	PRK12810, gltD, glutamate synthase subunit beta; Reviewed.	0
NZ_CP030848.1\|WP_149527117.1\|3826178_3827159_-\|deoxyhypusine-synthase	gnl\|CDD\|376661	pfam01916, DS, Deoxyhypusine synthase. Eukaryotic initiation factor 5A (eIF-5A) contains an unusual amino acid, hypusine [N epsilon-(4-aminobutyl-2-hydroxy)lysine]. The first step in the post-translational formation of hypusine is catalyzed by the enzyme deoxyhypusine synthase (DS) EC:1.1.1.249. The modified version of eIF-5A, and DS, are required for eukaryotic cell proliferation.	1.00486e-36
NZ_CP030848.1\|WP_149527125.1\|3841921_3843622_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.22374e-167

>NZ_CP030848.1|WP_149527120.1|3833253_3834702_+|glutamate-synthase-small-subunit
MGKATGFLEYERTLPQKDAVESRRQNYQEFVQPYTDDQLNNQAARCMNCGIPFCHSGCPLGNVIPEFNDAVYDGKWEEAYQILSSTNNFPEFTGRICPAPCESACVLGINKSPVAIEEIEKHIIEIAYKKGYVQPNKSYLKTGKRVAVVGSGPSGLAAAAQLNKAGHDVVVYERDDKVGGLLRYGIPDFKLDKSVIDRRISIMEQSGVEFRTNAEVGKNVPAQELKAYDAIVLAGGSTIPRDLKIPGRELKGVHFAMDFLKQQNKRVGNSPIEVEEIHAAGKNVLVIGGGDTGSDCVGTSNRHGAISVTQFELMPTPPQSRTDAMPWPTYPMLLKTTTSHEEGCQRHWSISTKEFLGDENGNLRAAKVVDLSWETDENGRPTKFAEVEGSEREIPCELVTLAMGFLNPQHEGLLQQLGVDLDPRGNVLASEAEYKTNLSNVFTAGDMRRGQSLVVWAISEGRECARKVDEFLMGKSELENRH
>NZ_CP030848.1|WP_149527119.1|3828735_3833235_+|glutamate-synthase-large-subunit
MQQEGLYNPAFEHDACGVGFVAHIKGQKSHRQVQDALTMLENMEHRGACGCDPESGDGAGIMIQLPHEFLWEECINLGIQLQEPGYYGVGMLFLPKEGEMNAICRQVIAEAAAERNMELLGYRPVPVDRAGIGPTALSAEPEIVQFFISRPEGVGNTEDFERKLYVLRRLIIQKIKTHQAYPLPLYIASLSCKTIVYKGQLTTYQVGSYFKDLHDPRVVSAFGLVHSRFSTNTFPSWSLAQPFRMIAHNGEINTLTGNLNWFYAGVRALSSPYFTDEEMEILLPVVDRGQSDSACLDNVVELLLHSGRSLPHVMLMLVPEAWDGNDQMDPLKKAFYEYHATLMEPWDGPAALCFTDGNIIGATLDRNGLRPLRYAITNDDRVVVASEAGALPIDEATIIKKGRQQPGKIFVVDMEAGKIRSDEEVKGALVRQQPYGEWINNYKIKLEELADPRVTFTYLSKESVFKYQQSFGYSREDIETILTPMALTGYEPIGSMGTDVPLAVLSDQPQHISSYFKQFFAQVTNPPIDPIRERLVMSLATFIGNAGNILIEDKKFCHCVTLEHPILTSSELEKLRSIDTGVFQAKTIQSYFRADGKSGSLEAGLERLCRYADDAVKDGFEVIILSDRAIDSQHCAIPSLLAVSAVHHHLIKTGNRGAVGLVVEAGDAWEVHHFACLLAFGATAINPYMALASIRTMREQGQLDTDLTWDDLKKNYVKAVCNGLLKIFSKMGISTLQSYHGAQIFEVLGIDSSVVDKYFCGAVSRIGGLTLDDIAKEALAKHWRGFEHSRVTSTLLPEGGLYQWKRRGEGHLWNPQTVHLLQQACRTDSFDTYKKYASLINNQKEHMFTLRGLLEFAKHRTPISIDQVEPASDIMKRFATGAMSFGSISHEAHSTLAIAMNRIGGKSNTGEGGEDEIRYAKLPNGDSMRSAIKQVASARFGVTSNYLTQADEIQIKMAQGAKPGEGGQLPGHKVDDWIAKVRHSTPGVGLISPPPHHDIYSIEDLAQLIFDLKNANRDARINVKLVSKAGVGTIAAGVAKAHADVILIAGYDGGTGASPISSIKHAGLPWELGLAEAHQTLVQNKLRSRVVLQADGQMKTGRDLVIATLLGAEEWGVATAALVAGGCIMMRKCHLNTCPVGVATQDPELRKLFSGKPEDVVNLFRFLAEEMREIMAQLGFRTINEMVGRAQFLKKREDLPHWKASKIDFSGILHVAANASGQTLYNTEEQDHGMSMILDWGLLTQAKPALESKTPVFGTFHVKNTDRTIGTLLSNEISKIYGSEGLPDNSINFKFKGSAGQSFGAFNTKGISFELEGEANDYVGKGLSGAQLAIYPAAESSLVPDENIIIGNVALYGATSGHLFINGRAGERFAVRNSGATAVVEGIGDHGCEYMTGGRALILGETGRNFAAGMSGGIAWVYDLDGNFRENCNKEMVDLDPLDAEDETAIINLLKRHILLTKSERANTILTNWAAEKSKFIKVFPREYKQVIQVKLVTA
>NZ_CP030848.1|WP_149527118.1|3827425_3828526_-|dipeptide-epimerase
MTITEIEIYRLSIPMEPFVIATGTMDYAQNTFIRVRTDSEHFGVGECSAFPMIVGETQNTCIALAKDFAKIWLGKDPLQIAERMAELHLYIAGNATIKSAFDMALYDLAAKAAGQPLYQFLGGKVRDIVTDITLGIASPEEMAAKALKLHEGGAVALKVKLGKKPQDDVARIKAIRQVVGFDIPIRIDANQGWTYEEAVEALQGLEPLKIQFCEQPMRTYNDHLLAQLRSETIVPIMADESVYNHHDAERLCRTDSCDYINIKFSKSSGITESLKIQAVAQEYNIPCMIGGMLESRLALAAKAHFAYAAPNVKFFDLDTCMVGHLEDPVIGGIRYDGYQIHIGEGFGIGADMDPAFLETCDKWVIS
>NZ_CP030848.1|WP_149527117.1|3826178_3827159_-|deoxyhypusine-synthase
MSTQRGPISQFIEKNYLHFNAASLVDAAKGYETHLAEGGKMLVSLAGAMSTAELGISLAEMIRQDKVAIISCTGANLEEDVMNLVAHSHYKRVPHYRDLTPQDEWELLENHYNRVTDTCIPEEEAFRRLQSHLEKAWKDAEAAGERYFPHEFLYKVVLSGDLEQYYEIDPKNSWILAAAEKNIPIICPGWEDSTTGNIFASYVIKGELNVHTVKTGIEYMIYLTEWYRANSGGKGVGFFQIGGGIAGDFPICVVPMMYQDLEWHDVPFWSYFCQISDSTTSYGSYSGAVPNEKITWGKLDTESPKFIVESDATIVAPLIFAWVLGQ
>NZ_CP030848.1|WP_149527759.1|3825598_3826102_-|hypothetical-protein
MSETIFTMGEETALPGGSIHNYPNQDIPQAAAAETAAEEFIFQGDKSTGVLFILRYPEYPYFSPAAEEAFLKTIGALQLNASNVAVVNLANPHNPNDWTRIMKFFQPKKITLLGVEPTSLKLPTIAHNSYMKGKIATVFNTFSFEEMFADVQKKKLFWGEFKTFIGS
>NZ_CP030848.1|WP_149527116.1|3824965_3825535_-|non-canonical-purine-NTP-diphosphatase
MELIFATNNAHKLEEVQQMVGEQFTLKSLADIGCEDDIPETGVTFQENAQQKTDYLIAKYGVNCFGDDSGLEIDALNGEPGVYSARYSGSRDMEKNIDLVLERLGDTENRSARFKTVISLFLNGEQHFFEGTVEGNIIKERIGTAGFGYDPIFIPHGYEHTFAEMSMEEKNRISHRAQAIAKLVEFLKG
>NZ_CP030848.1|WP_149527758.1|3822466_3824668_+|hypothetical-protein
MRLLSSSSSRFINQKILRSYHPVYEHKGSTLSADSGDLYKDDIGREFFEAHGNIVITQTSGSVIYGTHLHYDAASQQAVLTKNVRMVDGQTTLTTNYLTYNMRSQRGTYRNGGRIEGQGDTITSQNAYYFETSKDAYFNNKVVVRSPNVIIYTDTMQYNTMYRDAFFFGPTNIKGRKGENLYTEKGTYNTAFGIAKFNKNNLYTEGSRFLKGDSLFYDRNRGIGEAFRNVVFVDTLDKFYSNGGYGKYIEADQSILMTDKPLVKYVIQNDTTKQAADSLSTDSLQANKNLSKREIRKLEKEKEKELKAQEKQLTEKDISSTTDSTENKAVVPIKEPPKVDTAYMTADTLYSKVIFVRDYKPLDLKLDRNGGQIEESTEVDYGDMDDSTSFDDTDSLSIGEPILEKTLETAEPKILKKSETVKPVTPAKKAPAKAKVPDSMNIEVTTKADSVLRRKAEMPTGTEHDDLLSDALKTAQTADTLLKDSTQIFADTARTRIVRANYNVRVFKSDLQAVADSVYYGMVDSMFRFMGKPMIWSDGSQISADTIFMQIKNGKMDNALLKQNAFMVNAVLDTLKFNQLKGRKITAFFANNAIERLFVDGNAENLVFSTNDKTNTITEMFHDRSSRIKITMENNKIIDYVSIRKIDQKIYPFKLVTQELEVLPGFQWKPEDRPKSVEDMLNRKRAGQSLISEPDDEDEGDENTGEIKTEATKSIDTKKAEQTEKILEEATEN
>NZ_CP030848.1|WP_149527115.1|3820902_3822228_-|tRNA-lysidine(34)-synthetase-TilS
MATINKLKSFIKEKQLLSTADKVLLAVSGGKDSMLMACLFHDLGYQCIIAHCNFQLRGEDSDLDEALVRQYADELGYPCFVKRFDTEKYAKKHKESIQMAARTLRYAWFEELKAAERCTVICIAQHLNDHIETALLNLTRSTGLQGLLGISPRREDIVRPLLCLTAEEVEKTVGEYNVRYRDDQSNFSTKYARNKVRLEIIPKFKEIQPEFEAIMIQNIKHFEDSYNFIKKQVEAIRAQVFQEEESRTVITMESLAPYINDSYLLFELFKPYNFNKEILIDLQDCFDRGMGQLFESNSHELLLDRDKLILRSRGDVGKLEIKIEKGMKVVDLGNAKLKLKKGSIDLLHKEKHQVDVDADLLIYPLEIRNWREGDVFVPLGMKGRKKLSDFFIQQKIDRFEKNRVPILLNGNGEIIWIINHRLDNRYKVTENTKKVLTLVYK
>NZ_CP030848.1|WP_149527114.1|3820411_3820897_-|hypothetical-protein
MEEQLLFKEKQYLGRDMTWISVRLILALFCFIAYYINLEHMLSRQLFFIVGGGILIVSIIMLYMISYRTKVFPTHVLLSGLWTTSVVKIDLSSIVKVEKKRYSSFIFNNPVYNLHKNGKIRFYSGGKDAVWLTDRDGLIYVIGSQHPQELFNAIEEARGKS
>NZ_CP030848.1|WP_149527113.1|3820029_3820329_-|DUF4834-family-protein
MTFIYFLISIILFYYLFKFGMRLLMPFFMRKLTERLMNKQQQYANEGPFQQSYGDPFREYNQRETRHDGKVKVEFTPPKQSPKKGTATAGEFIDFEEVK
>NZ_CP030848.1|WP_094258934.1|3836392_3836746_+|transposase
MQEAERKLLSLLMPEGLLEYFQILEVDQVDNQLHIYLDELNIAPTGYENSKLESKGFMPSTEISDFPIRGQKVTLHIRRRRWTVLDTGDIITRDWNLVREGARMTTEFGLFLKKIFG
>NZ_CP030848.1|WP_149527684.1|3836786_3837722_+|transposase
MDGKQLQDQYKNHLSDFHDWDQKPHAESWTLFPENISEHLSIDETSFSNGELYTIVSSKSAKGRKGTILATIKGTQAEDIMAVLERIPLRSRNKVKEVTMDMAPNMAKAIRRCFRNARRVVDRFHVQKLAYDAVQELRIKYRWEVLDAESKKIMESRKRGTPYEPELLPNGDTLKQLLARSRHLLFKHPSRWSESQKNRAELLFMRFPKLKQAYDLGIALGDIFNKCRDKKVAFTKLGLWHNQVENAGIASFESVARSIAAHHQYILHYFDNRSTNASAESFNAKLKAFRSVFRGVRDTTFFLYRVMKLYA
>NZ_CP030848.1|WP_149527121.1|3838244_3839123_+|GTPase-Era
MSHKAGFVSIIGKPNAGKSTLMNALVGEKMSIITPKAQTTRHRIIGIVNDEDHQIVFSDTPGVIKPNYSLQESMMNFVMGSIIDADILLFVTDINEKYDENDVLEKLRNTSSPVAVVINKVDKSSEEEVKAKIEFWKEKINPDVIFPISALLGYNVESVMAYIKEKLPEHAAYYEKDELTDKSMRFFVSEIIREKVFKLYDKEIPYSTEVIITSFKEEPKITRIAAEIIVERDSQKNIIIGKAGAMIKKVGTYARQDIEEFIGGKVFLEMFVKVLPDWRSKKNYLKRFGYDD
>NZ_CP030848.1|WP_149527122.1|3839161_3840463_-|cation:proton-antiporter
MPNTIIIEIGIAVLLVALVGLLANRLRFSVIPFFIVIGMVLGNESYPGFVADGLASIGNEGFTQAVNSVWKFFTFTESKPFIDFMGRLGVLFLLFYLGLEFSVGRLIKSGKSIVAGGSFYVALNFVSGLLVGWMMDLPFKETMVLCGIMTSSSTAIVAKVLTDLKRTANPETEVIMGMIMFDDLFIAMHISFLSGLILTGSSSFWAVAGTSLLALGFILTFLILGRKLIPFIDKILQEKSSELFILIIFSLLFTIAGFSETIHVAEAIGALMAGLVFADSKYLKKIEGMVLPFKDFFGAMFFFSFGLSIDMYSLGGAVGWAAFAALITIIGNVASGYFATRFSNVKPKNSVDIGFTLSARGEFSIIMANIGKAGKLLPVIQSFVVVYVLILSIVSPLLTKESRNIWNKLSGQKEAPKRAKKKLSDLEAAVQEP
>NZ_CP030848.1|WP_149527123.1|3840472_3840952_-|cation:proton-antiporter-regulatory-subunit
MSIVRESDLIGIGKKYQIETEAGDNMVVVIHDDGRRELYRHEDEDNETHCVMTLSDEESRQVAGILGGLSYKPKALETIEVALDDLRIEWYKVESSNDGVNKSIGELEVRQRTGASIIAAIREDETIINPGPDYVIQPGATLVIAGKLKNIKLLKEILL
>NZ_CP030848.1|WP_149527124.1|3841023_3841806_-|MBL-fold-metallo-hydrolase
MVRAYSLYEGSYSVDKSKKFIPFDPKKDDPKDRPGSLFIHVHPFLVETKGGLVLLDTGLGRRTEDDELMIHANIKKLGFDIEDVRYVLMSHLHKDHANGMVDFKDGSKRVAFPNAEYVIQEQEWEAAFSTESPSYRTDVFEVLQRSGNLLFVNGDGRLNDEIRYELSGGHSEFHQVFHIGTADEHFFFGGDELPEPEEIFRNFIAKYDYDGRRAKQLREEYWAAGAPEGWVFMFYHSKSIAIGRPEQREDGTYKIVDATK
>NZ_CP030848.1|WP_149527125.1|3841921_3843622_+|single-stranded-DNA-specific-exonuclease-RecJ
MQKRWVLKPKKDVGKINKLRDELGVNSIIAELLLNRDVETFEQARIFFRPSLDYLHDPFLMKGMDVAIARIEKAIGNNEKILIYGDYDVDGTTAVAVVYSFFRDFHSRIEYYIPDRYKEGYGISTAGIDYAHENGFSLIIALDCGIKANDKIAYANSKNIDFIIGDHHLPGDELPDAVAVLDPKRSDCPYPYKELSGCGIGFKIIQAFIKQNSMDMELAYQYLDLVAVSIASDIVPITGENRILAHFGLIKLNGNASCGLQALINLSSHKTGQFSVNDIVFQIGPRINAAGRIDHAKDAVQLLIAKSLSDAKEFSVNIDDQNNVRKDFDLRITEEALSLLDNDVLQHSKKTTVLYKSDWHKGVIGIVASRLTERYYRPTIILTETNGHIAGSARSVIGFDLYEALSECSDLLDQYGGHKYAAGLTMQHSNVALFQERFEEVVSKTIKPEMLQQEVLIEKDINLMDIDSKFYRILKQFEPFGPQNEAPIFMTKRVTAAGTAYIVGSTHLKFSVKQEDSYAFECIGFGLGEHVNVINEGKPFDICYSIEENNWRGKKNLQLNIKAIRF
>NZ_CP030848.1|WP_149527126.1|3843651_3844386_+|LPS-export-ABC-transporter-ATP-binding-protein
MILKAEHLIKKYKQRTVVNDVSFHVEQGEIVGLLGPNGAGKTTSFYMIVGLIKPNEGNVYLDDLEITADPMYRRAQRGIGYLAQEASVFRKLSVENNILSVLEIHYPNKAERKEKLEELLTEFSLHRVRKNRGDLLSGGERRRTEIARALAANPHFILLDEPFAGVDPIAVEEIQTIVAKLKTRNIGILITDHNVQETLSITDRAYLLTEGKIMLTGTPEEIANNELARKFYLGRHFELRRKKF
>NZ_CP030848.1|WP_149527127.1|3844407_3845919_+|GH3-auxin-responsive-promoter-family-protein
MALLNSLFTWIMKKRMHQIDLFMKYPHDVQEEWFQSLISAAEATEWGKKYDYNSILTPEQYKERVPIQDYDSLKGYIDRMIKGEQNILWPSDIKWFAKSSGTTADRSKFIPVSIEALEECHYQGGKDMLSIYCHNKPENKVFTGKSVVIGGSSQINNFSPDSYYGDLSSILIRNLPFWAEFKRTPNIEVTLNPNFEEKIEQICQITLKENVTSLAGVPTWNMVMANRILEITGKDNLLEVWPNLEFYSHGGVSFKPYREQFKKLIPTDNMYYLENYNASEGYFGLQDRSDSDDLLLMLDYGIYYEFLPMESLHEEHPKTLGLHEVEIGKNYALIITTNAGLWRYKIGDTIKFTSLSPYRFQISGRTKQYINTFGEEVIVDNADHALEAACKATEASIKDYTAGPVYFKDKGAGAHEWVIEFDKQPQDFNRFCEILDQTLREINSDYDAKRYKNMALSAPIIHNAPTDTFYQWMKSRGKLGGQNKVPRLANSREYLDPILKLLS
>NZ_CP030848.1|WP_149527128.1|3846877_3847948_+|branched-chain-amino-acid-aminotransferase
MSATEQISIRVEPTKTSRLSQVDFNNLKFGQIMSDHMLVANYENGQWTDVAIVPYGDLTLSPSMSALHYGQAIFEGIKGYKFADGTVSIFRPDKNWERFNKSAARLQMPEVPEEIFMDGLTKLLDVDREWIPSIEGTALYIRPFMFATEAALGVHPSISYKFIIITCPVGAYYSKPISLKVETHYTRAAEGGVGFSKNAGNYALSLYPTQLANNEGYDQIMWTDANEHKYIEEAGTANLIFRIGDTIITPHGDTILHGVTRRTIMELAEEWGYKAEQRKVSVQELIDGIKAGTVTEAFAAGTAATITHIDRIGFEGQDYTLPPVEGREFSLKVLSYLNDLRYGKSEDTHGWNLIVK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP030848_19	19.1\|3429727\|33\|NZ_CP030848\|CRISPRCasFinder	3429727-3429759	33	NZ_CP030848.1	3402436-3402468	0	1.0
NZ_CP030848_19	19.1\|3429727\|33\|NZ_CP030848\|CRISPRCasFinder	3429727-3429759	33	NZ_CP030848.1	3431174-3431206	1	0.97
NZ_CP030848_23	23.1\|3789724\|42\|NZ_CP030848\|CRISPRCasFinder	3789724-3789765	42	NZ_CP030848.1	1728266-1728307	1	0.976
NZ_CP030848_23	23.1\|3789724\|42\|NZ_CP030848\|CRISPRCasFinder	3789724-3789765	42	NZ_CP030848.1	3326324-3326365	1	0.976
NZ_CP030848_23	23.1\|3789724\|42\|NZ_CP030848\|CRISPRCasFinder	3789724-3789765	42	NZ_CP030848.1	3385835-3385876	1	0.976
NZ_CP030848_23	23.1\|3789724\|42\|NZ_CP030848\|CRISPRCasFinder	3789724-3789765	42	NZ_CP030848.1	3865467-3865508	1	0.976
NZ_CP030848_23	23.1\|3789724\|42\|NZ_CP030848\|CRISPRCasFinder	3789724-3789765	42	NZ_CP030848.1	4110171-4110212	1	0.976
NZ_CP030848_19	19.1\|3429727\|33\|NZ_CP030848\|CRISPRCasFinder	3429727-3429759	33	NZ_CP030848.1	4081496-4081528	2	0.939
NZ_CP030848_23	23.1\|3789724\|42\|NZ_CP030848\|CRISPRCasFinder	3789724-3789765	42	NZ_CP030848.1	2352263-2352304	2	0.952

1. spacer 19.1|3429727|33|NZ_CP030848|CRISPRCasFinder matches to position: 3402436-3402468, mismatch: 0, identity: 1.0

aagaaaggaaggatgcaaggatgaacaggatca	CRISPR spacer
aagaaaggaaggatgcaaggatgaacaggatca	Protospacer
*********************************

2. spacer 19.1|3429727|33|NZ_CP030848|CRISPRCasFinder matches to position: 3431174-3431206, mismatch: 1, identity: 0.97

aagaaaggaaggatgcaaggatgaacaggatca	CRISPR spacer
aagaaaggaaagatgcaaggatgaacaggatca	Protospacer
**********.**********************

3. spacer 23.1|3789724|42|NZ_CP030848|CRISPRCasFinder matches to position: 1728266-1728307, mismatch: 1, identity: 0.976

agaactttcatccctgttgctgtttcaaaggaaacatgaaag	CRISPR spacer
agaactttcatccctgttggtgtttcaaaggaaacatgaaag	Protospacer
******************* **********************

4. spacer 23.1|3789724|42|NZ_CP030848|CRISPRCasFinder matches to position: 3326324-3326365, mismatch: 1, identity: 0.976

agaactttcatccctgttgctgtttcaaaggaaacatgaaag	CRISPR spacer
agaactttcatccctgttggtgtttcaaaggaaacatgaaag	Protospacer
******************* **********************

5. spacer 23.1|3789724|42|NZ_CP030848|CRISPRCasFinder matches to position: 3385835-3385876, mismatch: 1, identity: 0.976

agaactttcatccctgttgctgtttcaaaggaaacatgaaag	CRISPR spacer
agaactttcatccctgttggtgtttcaaaggaaacatgaaag	Protospacer
******************* **********************

6. spacer 23.1|3789724|42|NZ_CP030848|CRISPRCasFinder matches to position: 3865467-3865508, mismatch: 1, identity: 0.976

agaactttcatccctgttgctgtttcaaaggaaacatgaaag	CRISPR spacer
agaactttcatccctgttggtgtttcaaaggaaacatgaaag	Protospacer
******************* **********************

7. spacer 23.1|3789724|42|NZ_CP030848|CRISPRCasFinder matches to position: 4110171-4110212, mismatch: 1, identity: 0.976

agaactttcatccctgttgctgtttcaaaggaaacatgaaag	CRISPR spacer
agaactttcatccctgttggtgtttcaaaggaaacatgaaag	Protospacer
******************* **********************

8. spacer 19.1|3429727|33|NZ_CP030848|CRISPRCasFinder matches to position: 4081496-4081528, mismatch: 2, identity: 0.939

aagaaaggaaggatgcaaggatgaacaggatca	CRISPR spacer
aagaaaggaaggatgcaaggattagcaggatca	Protospacer
********************** *.********

9. spacer 23.1|3789724|42|NZ_CP030848|CRISPRCasFinder matches to position: 2352263-2352304, mismatch: 2, identity: 0.952

agaactttcatccctgttgctgtttcaaaggaaacatgaaag	CRISPR spacer
agaactttcattcctgttggtgtttcaaaggaaacatgaaag	Protospacer
***********.******* **********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NC_017140	Bacillus megaterium WSH-002 plasmid WSH-002_p2, complete sequence	2867-2894	4	0.857
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NZ_CP054576	Staphylococcus saprophyticus strain UTI-050 plasmid pUTI-050-1, complete sequence	23814-23841	5	0.821
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NC_007352	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 plasmid pSSP2, complete sequence	443-470	5	0.821
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	AP014324	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S33-C64, * SEQUENCING IN PROGRESS *	7441-7468	5	0.821
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NZ_CP022094	Staphylococcus saprophyticus strain FDAARGOS_355 plasmid unnamed3, complete sequence	15477-15504	5	0.821
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NZ_CP035297	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 strain ATCC 15305 plasmid unnamed3, complete sequence	6409-6436	5	0.821
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NC_009705	Yersinia pseudotuberculosis IP 31758 plasmid p_153kb, complete sequence	88765-88792	6	0.786
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	NZ_CP021170	Paenibacillus bovis strain BD3526 plasmid unnamed1, complete sequence	42473-42500	6	0.786
NZ_CP030848_8	8.1\|2202414\|28\|NZ_CP030848\|CRISPRCasFinder	2202414-2202441	28	MN693193	Marine virus AFVG_25M440, complete genome	27583-27610	6	0.786
NZ_CP030848_3	3.1\|1502088\|29\|NZ_CP030848\|CRISPRCasFinder	1502088-1502116	29	NZ_CP010612	Phaeobacter inhibens strain P92 plasmid pP92_b, complete sequence	65928-65956	7	0.759
NZ_CP030848_1	1.1\|1019072\|30\|NZ_CP030848\|CRISPRCasFinder	1019072-1019101	30	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	230798-230827	8	0.733
NZ_CP030848_11	11.1\|2500901\|32\|NZ_CP030848\|CRISPRCasFinder	2500901-2500932	32	HG531805	Clostridium phage CDMH1 complete genome	31120-31151	8	0.75
NZ_CP030848_11	11.1\|2500901\|32\|NZ_CP030848\|CRISPRCasFinder	2500901-2500932	32	MN694362	Marine virus AFVG_250M129, complete genome	16371-16402	9	0.719
NZ_CP030848_21	21.1\|3640511\|32\|NZ_CP030848\|CRISPRCasFinder	3640511-3640542	32	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	368125-368156	10	0.688

1. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NC_017140 (Bacillus megaterium WSH-002 plasmid WSH-002_p2, complete sequence) position: , mismatch: 4, identity: 0.857

taaatctaataaaaaactattct-agcat	CRISPR spacer
taaatctaataaaaaattcttctctgca-	Protospacer
****************.* ****  ***

2. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NZ_CP054576 (Staphylococcus saprophyticus strain UTI-050 plasmid pUTI-050-1, complete sequence) position: , mismatch: 5, identity: 0.821

taaatctaataaaaaactattctagcat	CRISPR spacer
tgatgctaataaaaaattattcaagcat	Protospacer
*.*  ***********.***** *****

3. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NC_007352 (Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 plasmid pSSP2, complete sequence) position: , mismatch: 5, identity: 0.821

taaatctaataaaaaactattctagcat	CRISPR spacer
tgatgctaataaaaaattattcaagcat	Protospacer
*.*  ***********.***** *****

4. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to AP014324 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S33-C64, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.821

taaatctaataaaaaactattctagcat	CRISPR spacer
taaatctaataaagaactattagaggaa	Protospacer
*************.*******  ** *

5. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NZ_CP022094 (Staphylococcus saprophyticus strain FDAARGOS_355 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.821

taaatctaataaaaaactattctagcat	CRISPR spacer
tgatgctaataaaaaattattcaagcat	Protospacer
*.*  ***********.***** *****

6. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NZ_CP035297 (Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292 strain ATCC 15305 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.821

taaatctaataaaaaactattctagcat	CRISPR spacer
tgatgctaataaaaaattattcaagcat	Protospacer
*.*  ***********.***** *****

7. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NC_009705 (Yersinia pseudotuberculosis IP 31758 plasmid p_153kb, complete sequence) position: , mismatch: 6, identity: 0.786

taaatctaataaaaaactattctagcat-	CRISPR spacer
taaagctaataaaaaactatt-tggtgcc	Protospacer
**** **************** *.*...

8. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to NZ_CP021170 (Paenibacillus bovis strain BD3526 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

taaatctaataaaaaactattctagcat	CRISPR spacer
ttcttctaataaaaaactattccaacag	Protospacer
*   ******************.*.**

9. spacer 8.1|2202414|28|NZ_CP030848|CRISPRCasFinder matches to MN693193 (Marine virus AFVG_25M440, complete genome) position: , mismatch: 6, identity: 0.786

taaatctaataaaaaactattctagcat	CRISPR spacer
taaatctaataaaaaagtatttgattct	Protospacer
**************** ****. * . *

10. spacer 3.1|1502088|29|NZ_CP030848|CRISPRCasFinder matches to NZ_CP010612 (Phaeobacter inhibens strain P92 plasmid pP92_b, complete sequence) position: , mismatch: 7, identity: 0.759

cgcgggatgtttcgtttggatgtttgttt	CRISPR spacer
cgcgggatgtttccgttggatgtgaatcg	Protospacer
*************  ********  .*.

11. spacer 1.1|1019072|30|NZ_CP030848|CRISPRCasFinder matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 8, identity: 0.733

caaggatgggcaggatcttgtagaagggta	CRISPR spacer
ccaggaagggcaggatcttgtagagcatcc	Protospacer
* **** *****************. . .

12. spacer 11.1|2500901|32|NZ_CP030848|CRISPRCasFinder matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 8, identity: 0.75

tggaaacatgaaagttttttctgaaagggtct	CRISPR spacer
tactaacatgaaagttgtttcagaaaggttag	Protospacer
*.  ************ **** ****** *

13. spacer 11.1|2500901|32|NZ_CP030848|CRISPRCasFinder matches to MN694362 (Marine virus AFVG_250M129, complete genome) position: , mismatch: 9, identity: 0.719

tggaaacatgaaagttttttctgaaagggtct	CRISPR spacer
cttaaacatgaaagttgtttctgcaaagaaca	Protospacer
.  ************* ****** **.*. *

14. spacer 21.1|3640511|32|NZ_CP030848|CRISPRCasFinder matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 10, identity: 0.688

ctatcctgttaatccttgcatccttcctttca	CRISPR spacer
tggatggcttaatcctggcaaccttcctttca	Protospacer
. . .   ******** *** ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

170017 : 177329

Escherichia_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149524342.1\|170017_171298_+	AAA family ATPase	G3MBE0	Bacillus_virus	9.1e-89	41.7
WP_149524343.1\|171323_171848_+	DNA polymerase III subunit epsilon	A0A0R6PHP9	Moraxella_phage	1.4e-11	28.6
WP_149524344.1\|171850_172840_+	NTP transferase domain-containing protein	A0A1V0SH58	Hokovirus	1.3e-31	31.3
WP_149524345.1\|172964_173750_+	protein tyrosine phosphatase	NA	NA	NA	NA
WP_149524346.1\|173953_175003_+	dTDP-glucose 4,6-dehydratase	A0A291LAD7	Escherichia_phage	8.8e-90	51.5
WP_149524347.1\|175019_175565_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	2.7e-42	51.4
WP_149527608.1\|175564_176446_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	6.6e-38	39.6
WP_149524348.1\|176459_177329_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.6e-92	62.5

DBSCAN-SWA_2

1288553 : 1357313

Streptococcus_phage(16.67%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149525197.1\|1288553_1289864_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_149525198.1\|1290275_1291376_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	NA	NA	NA	NA
WP_149525199.1\|1291721_1293020_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	2.8e-162	66.1
WP_149525200.1\|1293148_1293451_+	septum formation initiator family protein	NA	NA	NA	NA
WP_149525201.1\|1293478_1294183_-	FkbM family methyltransferase	NA	NA	NA	NA
WP_149525202.1\|1294228_1295593_-	pyridoxal-phosphate dependent enzyme	A0A1X9I5K7	Streptococcus_phage	1.7e-48	35.9
WP_149525203.1\|1295641_1296463_-	AMP nucleosidase	NA	NA	NA	NA
WP_149525204.1\|1296529_1297780_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	7.2e-115	53.7
WP_149525205.1\|1297785_1298484_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.1e-40	44.7
WP_149525206.1\|1298537_1298999_-	type I restriction enzyme HsdR N-terminal domain-containing protein	NA	NA	NA	NA
WP_149525207.1\|1299185_1300193_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_149525208.1\|1300200_1300770_+	hypothetical protein	NA	NA	NA	NA
WP_149525209.1\|1301625_1304796_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_149525210.1\|1304825_1305965_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_149525211.1\|1305989_1307321_-	TolC family protein	NA	NA	NA	NA
WP_149525212.1\|1307330_1307999_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_149525213.1\|1308345_1308771_-	c-type cytochrome	NA	NA	NA	NA
WP_149525214.1\|1308770_1309412_-	SCO family protein	NA	NA	NA	NA
WP_149525215.1\|1309418_1309847_-\|transposase	transposase	NA	NA	NA	NA
WP_149525216.1\|1309857_1310379_-	DUF4442 domain-containing protein	NA	NA	NA	NA
WP_149525217.1\|1310469_1311696_+	MFS transporter	NA	NA	NA	NA
WP_149525218.1\|1311896_1312526_-	uridine kinase	H2EER4	Moumouvirus	8.6e-24	34.4
WP_149525219.1\|1312534_1313434_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_149525220.1\|1313443_1314226_-	hypothetical protein	NA	NA	NA	NA
WP_149525221.1\|1314231_1315584_+	nodulation protein NfeD	NA	NA	NA	NA
WP_149525222.1\|1315629_1315824_-	hypothetical protein	NA	NA	NA	NA
WP_149525223.1\|1316248_1317811_-	hypothetical protein	NA	NA	NA	NA
WP_149525224.1\|1317889_1319041_-	hypothetical protein	NA	NA	NA	NA
WP_149525225.1\|1319215_1320688_+\|tRNA	proline--tRNA ligase	A0A2K9L3R9	Tupanvirus	1.0e-96	38.7
WP_149525226.1\|1320691_1321480_+	GDP-L-fucose synthase	NA	NA	NA	NA
WP_149525227.1\|1321509_1322658_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	1.3e-22	28.5
WP_149525228.1\|1322733_1322988_+	hypothetical protein	NA	NA	NA	NA
WP_149525229.1\|1323161_1323779_+	hypothetical protein	NA	NA	NA	NA
WP_149525230.1\|1323906_1324323_-	hypothetical protein	NA	NA	NA	NA
WP_149525231.1\|1324364_1326029_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_149527652.1\|1326071_1326698_-	sprT domain-containing protein	NA	NA	NA	NA
WP_149525232.1\|1326802_1328455_+	DNA repair protein RecN	NA	NA	NA	NA
WP_149525233.1\|1328498_1328912_-	hypothetical protein	NA	NA	NA	NA
WP_149525234.1\|1329061_1331626_-	AAA domain-containing protein	A0A0A8J958	Klebsiella_phage	7.3e-130	39.5
WP_149525235.1\|1331796_1333479_+	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	4.0e-52	30.4
WP_149525236.1\|1333489_1334677_+	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	7.5e-21	26.3
WP_149525237.1\|1334676_1335735_+	response regulator	W8CYM9	Bacillus_phage	5.2e-13	36.9
WP_149525238.1\|1336222_1336642_+	lactate dehydrogenase	NA	NA	NA	NA
WP_149525239.1\|1336643_1338008_+	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_149525240.1\|1338018_1340415_+	HAD-IC family P-type ATPase	NA	NA	NA	NA
WP_149525241.1\|1340425_1340605_+	cbb3-type cytochrome oxidase assembly protein CcoS	NA	NA	NA	NA
WP_149525242.1\|1340677_1341043_+	hypothetical protein	NA	NA	NA	NA
WP_149525243.1\|1341154_1342261_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_149525244.1\|1342278_1346847_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_149525245.1\|1353282_1353648_+\|transposase	transposase	NA	NA	NA	NA
WP_149525246.1\|1353658_1354612_+\|transposase	transposase	NA	NA	NA	NA
WP_149525247.1\|1355026_1355977_+	TIGR01212 family radical SAM protein	NA	NA	NA	NA
WP_149525248.1\|1356086_1357313_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	4.1e-38	28.9

DBSCAN-SWA_3

1904771 : 1949212

Flavobacterium_phage(50.0%)

tail,integrase,transposase

attL 1895835:1895850|attR 1922498:1922513

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1895835:1895850	attL	NA	NA	NA	NA
WP_149525631.1\|1904771_1906031_+\|integrase	tyrosine-type recombinase/integrase	A5X9F3	Aeromonas_virus	1.2e-05	27.3
WP_149525632.1\|1906067_1909118_-	hypothetical protein	NA	NA	NA	NA
WP_149525633.1\|1909133_1910198_-	hypothetical protein	NA	NA	NA	NA
WP_149525634.1\|1910199_1910895_-	hypothetical protein	NA	NA	NA	NA
WP_149525635.1\|1910891_1911200_-	hypothetical protein	NA	NA	NA	NA
WP_149525636.1\|1911243_1913172_-	hypothetical protein	NA	NA	NA	NA
WP_149525637.1\|1913174_1917359_-\|tail	phage tail tape measure protein	A0A1B0WN72	Flavobacterium_phage	3.0e-88	29.0
WP_149525638.1\|1917348_1917741_-	hypothetical protein	NA	NA	NA	NA
WP_149525639.1\|1918121_1918697_+	hypothetical protein	NA	NA	NA	NA
WP_149525640.1\|1918727_1919039_-	hypothetical protein	NA	NA	NA	NA
WP_149525641.1\|1919051_1919486_-	hypothetical protein	NA	NA	NA	NA
WP_149525642.1\|1919482_1920130_-	hypothetical protein	A0A1B0WMF2	Flavobacterium_phage	9.5e-10	27.1
WP_149525643.1\|1920347_1921289_-	hypothetical protein	NA	NA	NA	NA
WP_149525644.1\|1921293_1922658_-	hypothetical protein	H7BUQ7	unidentified_phage	4.1e-71	35.1
1922498:1922513	attR	NA	NA	NA	NA
WP_149525645.1\|1922654_1922906_-	hypothetical protein	NA	NA	NA	NA
WP_149525646.1\|1922994_1924053_-	hypothetical protein	NA	NA	NA	NA
WP_149525647.1\|1924064_1924298_-	hypothetical protein	NA	NA	NA	NA
WP_149525648.1\|1924381_1926139_-	hypothetical protein	A0A1B0WMQ6	Flavobacterium_phage	2.1e-112	39.6
WP_149525649.1\|1926161_1927109_-	hypothetical protein	NA	NA	NA	NA
WP_149525650.1\|1927148_1927796_-	hypothetical protein	NA	NA	NA	NA
WP_149525651.1\|1927816_1928521_-	hypothetical protein	NA	NA	NA	NA
WP_149525652.1\|1928535_1928991_-	DUF882 domain-containing protein	NA	NA	NA	NA
WP_149525653.1\|1928980_1930003_-	hypothetical protein	NA	NA	NA	NA
WP_149525654.1\|1930052_1930598_-	hypothetical protein	NA	NA	NA	NA
WP_149525655.1\|1930679_1932197_-	hypothetical protein	NA	NA	NA	NA
WP_149525656.1\|1932231_1933128_-	hypothetical protein	A0A1B0WM92	Flavobacterium_phage	1.8e-27	33.1
WP_149525657.1\|1933265_1933652_-	hypothetical protein	NA	NA	NA	NA
WP_149525658.1\|1933653_1934190_-	hypothetical protein	NA	NA	NA	NA
WP_149525659.1\|1934930_1935350_+	hypothetical protein	NA	NA	NA	NA
WP_149525660.1\|1935874_1936966_-	hypothetical protein	NA	NA	NA	NA
WP_149525661.1\|1936965_1937244_-	hypothetical protein	NA	NA	NA	NA
WP_149525662.1\|1938017_1938779_-	hypothetical protein	A0A219YFC7	Ochrobactrum_phage	1.7e-21	34.9
WP_149525663.1\|1938778_1939006_-	hypothetical protein	NA	NA	NA	NA
WP_149525664.1\|1939124_1939502_-	hypothetical protein	NA	NA	NA	NA
WP_149525665.1\|1939773_1940070_-	hypothetical protein	NA	NA	NA	NA
WP_149525666.1\|1940078_1940276_-	hypothetical protein	NA	NA	NA	NA
WP_149525667.1\|1940294_1943276_-	hypothetical protein	H7BUS3	unidentified_phage	1.0e-138	33.4
WP_149525668.1\|1943584_1943971_-	hypothetical protein	NA	NA	NA	NA
WP_149525669.1\|1943982_1944561_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149525670.1\|1944637_1944886_-	hypothetical protein	NA	NA	NA	NA
WP_149525671.1\|1945000_1945381_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149525672.1\|1945395_1945617_+	hypothetical protein	NA	NA	NA	NA
WP_149525673.1\|1945659_1946169_+	hypothetical protein	NA	NA	NA	NA
WP_149525674.1\|1946440_1946794_+\|transposase	transposase	NA	NA	NA	NA
WP_149527675.1\|1946834_1947770_+\|transposase	transposase	NA	NA	NA	NA
WP_149525674.1\|1947882_1948236_+\|transposase	transposase	NA	NA	NA	NA
WP_149527675.1\|1948276_1949212_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2086978 : 2122462

Wolbachia_phage(40.0%)

protease,integrase,transposase

attL 2085210:2085224|attR 2100622:2100636

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2085210:2085224	attL	NA	NA	NA	NA
WP_149525777.1\|2086978_2087344_+\|transposase	transposase	NA	NA	NA	NA
WP_149525778.1\|2087354_2088308_+\|transposase	transposase	NA	NA	NA	NA
WP_149525779.1\|2088569_2089763_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149525780.1\|2089759_2090524_+	hypothetical protein	NA	NA	NA	NA
WP_149525781.1\|2090642_2090915_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149525782.1\|2090928_2091861_+	AAA family ATPase	NA	NA	NA	NA
WP_149525783.1\|2091954_2092794_+	toprim domain-containing protein	NA	NA	NA	NA
WP_149525784.1\|2092878_2093211_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_149525785.1\|2093191_2094091_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_149525786.1\|2094102_2094759_+	hypothetical protein	NA	NA	NA	NA
WP_149525787.1\|2095048_2095507_+	JAB domain-containing protein	A0A1B2LRS6	Wolbachia_phage	1.7e-13	37.9
WP_149525788.1\|2095517_2096012_-	hypothetical protein	NA	NA	NA	NA
WP_149525789.1\|2096085_2096307_-	hypothetical protein	NA	NA	NA	NA
WP_149525790.1\|2096379_2096622_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149527682.1\|2096694_2097363_+	metallophosphoesterase	A0A1V0SET9	Hokovirus	9.7e-26	34.8
WP_149525791.1\|2097438_2100141_+	N-6 DNA methylase	Q6NE04	Leptospira_phage	3.3e-157	38.7
WP_149525792.1\|2100137_2101256_+	DUF1016 family protein	Q9JMP5	Wolbachia_phage	1.1e-48	31.3
2100622:2100636	attR	NA	NA	NA	NA
WP_149525793.1\|2101304_2103296_+	ATP-dependent helicase	NA	NA	NA	NA
WP_149525794.1\|2103288_2104488_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_149525795.1\|2104595_2106656_+	hypothetical protein	NA	NA	NA	NA
WP_149527683.1\|2108246_2109590_+	AAA domain-containing protein	K4I1H4	Acidithiobacillus_phage	3.2e-12	31.3
WP_149525796.1\|2109589_2110987_+	restriction endonuclease	NA	NA	NA	NA
WP_094258934.1\|2111264_2111618_+\|transposase	transposase	NA	NA	NA	NA
WP_149527684.1\|2111658_2112594_+\|transposase	transposase	NA	NA	NA	NA
WP_149525797.1\|2113035_2113512_-	RecX family transcriptional regulator	NA	NA	NA	NA
WP_149525798.1\|2113581_2116017_+	bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase	NA	NA	NA	NA
WP_149525799.1\|2116019_2116652_+	DUF502 domain-containing protein	NA	NA	NA	NA
WP_149525800.1\|2116629_2117235_+	hypothetical protein	NA	NA	NA	NA
WP_149525801.1\|2117677_2118076_-	hypothetical protein	NA	NA	NA	NA
WP_149525802.1\|2118192_2119251_-	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_149527685.1\|2119319_2121404_-	polyphosphate kinase 1	NA	NA	NA	NA
WP_149525803.1\|2121484_2121868_-	hypothetical protein	NA	NA	NA	NA
WP_149525804.1\|2121883_2122462_-\|protease	DJ-1/PfpI/YhbO family deglycase/protease	NA	NA	NA	NA

DBSCAN-SWA_5

4128996 : 4195091

Acanthocystis_turfacea_Chlorella_virus(20.0%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149527333.1\|4128996_4129791_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_149527334.1\|4129787_4131227_-	M28 family peptidase	NA	NA	NA	NA
WP_149527335.1\|4131391_4132309_-	TIM barrel protein	NA	NA	NA	NA
WP_149527336.1\|4132312_4133635_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_149527337.1\|4133657_4135172_-	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_149527338.1\|4135182_4138482_-	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
WP_149527339.1\|4138571_4139810_-	DUF4974 domain-containing protein	NA	NA	NA	NA
WP_149527340.1\|4139881_4140484_-	RNA polymerase sigma-70 factor	NA	NA	NA	NA
WP_149527341.1\|4140677_4141331_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_149527342.1\|4141387_4142329_+	NAD-dependent epimerase/dehydratase family protein	M1I5W5	Acanthocystis_turfacea_Chlorella_virus	3.1e-102	58.9
WP_149527343.1\|4143468_4143738_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_149527344.1\|4144041_4144944_+	class A beta-lactamase	NA	NA	NA	NA
WP_149527345.1\|4147243_4147852_+	RNA polymerase sigma-70 factor	NA	NA	NA	NA
WP_149527346.1\|4147947_4149090_+	DUF4974 domain-containing protein	NA	NA	NA	NA
WP_149527347.1\|4149193_4152553_+	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
WP_149527348.1\|4152564_4154043_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_149527782.1\|4154032_4155430_+	alpha-L-fucosidase	NA	NA	NA	NA
WP_149527349.1\|4155416_4156964_+	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_149527350.1\|4159778_4160099_-	hypothetical protein	NA	NA	NA	NA
WP_149527351.1\|4160119_4161598_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.4e-23	25.8
WP_149527352.1\|4161910_4163596_+	hypothetical protein	NA	NA	NA	NA
WP_149527783.1\|4163912_4164329_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149527353.1\|4164916_4165552_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_149527354.1\|4165551_4166199_-	hypothetical protein	NA	NA	NA	NA
WP_149527355.1\|4166242_4168321_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	4.3e-104	47.7
WP_149527356.1\|4168354_4168729_-	ribosome silencing factor	NA	NA	NA	NA
WP_149527357.1\|4168778_4169558_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_149527784.1\|4169643_4170102_+	sugar transporter	NA	NA	NA	NA
WP_149527358.1\|4170176_4171883_+	DUF255 domain-containing protein	NA	NA	NA	NA
WP_149527359.1\|4172219_4173194_+	6-phosphofructokinase	NA	NA	NA	NA
WP_149527360.1\|4173636_4174944_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_149527361.1\|4175026_4175473_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_149527362.1\|4175519_4177163_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_149527363.1\|4177178_4179980_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.4e-237	45.5
WP_149527364.1\|4180095_4180314_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_149527365.1\|4180303_4181572_-	exodeoxyribonuclease VII large subunit	NA	NA	NA	NA
WP_149527366.1\|4181662_4183393_+	serine hydrolase	NA	NA	NA	NA
WP_149527367.1\|4183389_4184559_+	membrane dipeptidase	NA	NA	NA	NA
WP_149527368.1\|4184600_4185242_-	hypothetical protein	NA	NA	NA	NA
WP_149527369.1\|4185241_4185748_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_149527370.1\|4185817_4187206_+	DNA repair protein RadA	NA	NA	NA	NA
WP_149527371.1\|4187469_4188597_-	redoxin domain-containing protein	NA	NA	NA	NA
WP_149527372.1\|4188643_4189477_-	TPM domain-containing protein	NA	NA	NA	NA
WP_149527373.1\|4189481_4189916_-	TPM domain-containing protein	NA	NA	NA	NA
WP_149527374.1\|4190080_4190659_-	LemA family protein	A0A1X9IGG1	Lactococcus_phage	3.9e-15	35.5
WP_149527375.1\|4190810_4192352_+	FAD-binding protein	NA	NA	NA	NA
WP_149527684.1\|4192625_4193561_-\|transposase	transposase	NA	NA	NA	NA
WP_094258934.1\|4193601_4193955_-\|transposase	transposase	NA	NA	NA	NA
WP_149526620.1\|4194182_4195091_-\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP030848

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection