CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP036524	[Clostridium] hylemonae DSM 15053 chromosome, complete genome	9 crisprs	csa3,DEDDh,WYL,cas3,DinG,cas2,cas1,cas4,cas7,cas8c,cas5	0	7	1	0

1. NZ_CP036524

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP036524_1

• CRISPR_ID: NZ_CP036524_1
• CRISPR_location: 228189-228482
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP036524_1

Consensus_repeat	Method
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	PILER-CR
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	CRT
TCGTTCCCCTTGTGGGAACGTGGATTGAAAC	CRISPRCasFinder

spacers of NZ_CP036524_1

>1.1|228221|32|NZ_CP036524|PILER-CR,CRT
GACATAGGGTACGTCCATAGTGATAAATATTA
>1.2|228285|35|NZ_CP036524|PILER-CR,CRT
ATCAAACCAGCCGTTGAAGATATGATACAGCCGCA
>1.3|228352|33|NZ_CP036524|PILER-CR,CRT
AACTCCGAACACTTCTACGCGAACCACTTTTTC
>1.4|228417|34|NZ_CP036524|CRT
GTGTTTTTGAATATGGAGGAGATCACCACTCTTT
>1.5|228221|33|NZ_CP036524|CRISPRCasFinder
GACATAGGGTACGTCCATAGTGATAAATATTAC
>1.6|228285|36|NZ_CP036524|CRISPRCasFinder
ATCAAACCAGCCGTTGAAGATATGATACAGCCGCAG
>1.7|228352|34|NZ_CP036524|CRISPRCasFinder
AACTCCGAACACTTCTACGCGAACCACTTTTTCG
>1.8|228417|35|NZ_CP036524|CRISPRCasFinder
GTGTTTTTGAATATGGAGGAGATCACCACTCTTTG

CRISPR arrays and Neighbor proteins around NZ_CP036524_1

CRISPR arrays

The CRISPR arrays of NZ_CP036524_1

>merge|NZ_CP036524|1|228189-228482|PILER-CR,CRT,CRISPRCasFinder
GTCGTTCCCCTTGTGGGAACGTGGATTGAAACGACATAGGGTACGTCCATAGTGATAAATATTACTCGTTCCCCTTGTGGGAACGTGGATTGAAACATCAAACCAGCCGTTGAAGATATGATACAGCCGCAGTCGTTCCCCTTGTGGGAACGTGGATTGAAACAACTCCGAACACTTCTACGCGAACCACTTTTTCGTCGTTCCCCTTGTGGGAACGTGGATTGAAACGTGTTTTTGAATATGGAGGAGATCACCACTCTTTGTCGTTCCCCTTGTGGGAACGAGGATTTAAAA

>NZ_CP036524|1|1|228189-228416|PILER-CR
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	GACATAGGGTACGTCCATAGTGATAAATATTA
CTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	ATCAAACCAGCCGTTGAAGATATGATACAGCCGCA
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	AACTCCGAACACTTCTACGCGAACCACTTTTTC
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC

>NZ_CP036524|1|1|228189-228482|CRT
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	GACATAGGGTACGTCCATAGTGATAAATATTA
CTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	ATCAAACCAGCCGTTGAAGATATGATACAGCCGCA
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	AACTCCGAACACTTCTACGCGAACCACTTTTTC
GTCGTTCCCCTTGTGGGAACGTGGATTGAAAC	GTGTTTTTGAATATGGAGGAGATCACCACTCTTT
GTCGTTCCCCTTGTGGGAACGAGGATTTAAAA

>NZ_CP036524|1|1|228190-228482|CRISPRCasFinder
TCGTTCCCCTTGTGGGAACGTGGATTGAAAC	GACATAGGGTACGTCCATAGTGATAAATATTAC
TCGTTCCCCTTGTGGGAACGTGGATTGAAAC	ATCAAACCAGCCGTTGAAGATATGATACAGCCGCAG
TCGTTCCCCTTGTGGGAACGTGGATTGAAAC	AACTCCGAACACTTCTACGCGAACCACTTTTTCG
TCGTTCCCCTTGTGGGAACGTGGATTGAAAC	GTGTTTTTGAATATGGAGGAGATCACCACTCTTTG
TCGTTCCCCTTGTGGGAACGAGGATTTAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006444413.1|229543_230578_+|flippase-like-domain-containing-protein	unknown	unknown	gnl|CDD|377103
NZ_CP036524.1|WP_040435795.1|218632_220633_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|224926
NZ_CP036524.1|WP_006444424.1|213383_214448_+|L-threonine-3-dehydrogenase	unknown	unknown	gnl|CDD|180054
NZ_CP036524.1|WP_006444417.1|223703_224873_-|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240630
NZ_CP036524.1|WP_006444406.1|235525_236110_+|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|238317
NZ_CP036524.1|WP_006444414.1|228831_229560_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239481
NZ_CP036524.1|WP_040435906.1|211018_211729_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP036524.1|WP_149301996.1|211815_213081_-|serine/threonine-transporter-SstT	unknown	unknown	gnl|CDD|184190
NZ_CP036524.1|WP_006444422.1|215740_218296_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225461
NZ_CP036524.1|WP_006444412.1|230599_231268_+|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|224104
NZ_CP036524.1|WP_040435793.1|233497_234277_+|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NZ_CP036524.1|WP_040435794.1|225155_227786_+|pyruvate,-phosphate-dikinase	unknown	unknown	gnl|CDD|236446
NZ_CP036524.1|WP_006444418.1|222265_223666_-|transporter	unknown	unknown	gnl|CDD|224671
NZ_CP036524.1|WP_006444405.1|236189_237116_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|107204
NZ_CP036524.1|WP_006444419.1|220791_222189_+|aminopeptidase	unknown	unknown	gnl|CDD|235018
NZ_CP036524.1|WP_006444411.1|231281_232163_+|phosphatidylserine-decarboxylase	unknown	unknown	gnl|CDD|179097
NZ_CP036524.1|WP_006444407.1|234293_235511_+|2-iminoacetate-synthase-ThiH	unknown	unknown	gnl|CDD|236425
NZ_CP036524.1|WP_006444409.1|232852_233485_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF	unknown	unknown	gnl|CDD|236320
NZ_CP036524.1|WP_006444423.1|214475_215675_+|glycine-C-acetyltransferase	unknown	unknown	gnl|CDD|235893
NZ_CP036524.1|WP_006444410.1|232651_232849_+|sulfur-carrier-protein-ThiS	unknown	unknown	gnl|CDD|340451

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006444413.1|229543_230578_+|flippase-like-domain-containing-protein	gnl|CDD|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	3.63546e-26
NZ_CP036524.1|WP_040435795.1|218632_220633_+|MBL-fold-metallo-hydrolase	gnl|CDD|224926	COG2015, COG2015, Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP036524.1|WP_006444424.1|213383_214448_+|L-threonine-3-dehydrogenase	gnl|CDD|180054	PRK05396, tdh, L-threonine 3-dehydrogenase; Validated.	0
NZ_CP036524.1|WP_006444417.1|223703_224873_-|alanine-dehydrogenase	gnl|CDD|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	1.83786e-126
NZ_CP036524.1|WP_006444406.1|235525_236110_+|thiamine-phosphate-synthase	gnl|CDD|238317	cd00564, TMP_TenI, Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.	3.95327e-39
NZ_CP036524.1|WP_006444414.1|228831_229560_+|phosphatase-PAP2-family-protein	gnl|CDD|239481	cd03386, PAP2_Aur1_like, PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.	4.83013e-12
NZ_CP036524.1|WP_040435906.1|211018_211729_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.52394e-14
NZ_CP036524.1|WP_149301996.1|211815_213081_-|serine/threonine-transporter-SstT	gnl|CDD|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NZ_CP036524.1|WP_006444422.1|215740_218296_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|225461	COG2909, MalT, ATP-dependent transcriptional regulator [Transcription].	2.67939e-38
NZ_CP036524.1|WP_006444412.1|230599_231268_+|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	7.20394e-32
NZ_CP036524.1|WP_040435793.1|233497_234277_+|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	4.56024e-142
NZ_CP036524.1|WP_040435794.1|225155_227786_+|pyruvate,-phosphate-dikinase	gnl|CDD|236446	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional.	0
NZ_CP036524.1|WP_006444418.1|222265_223666_-|transporter	gnl|CDD|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	2.04849e-45
NZ_CP036524.1|WP_006444405.1|236189_237116_+|cysteine-synthase-A	gnl|CDD|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	2.87047e-130
NZ_CP036524.1|WP_006444419.1|220791_222189_+|aminopeptidase	gnl|CDD|235018	PRK02256, PRK02256, putative aminopeptidase 1; Provisional.	0
NZ_CP036524.1|WP_006444411.1|231281_232163_+|phosphatidylserine-decarboxylase	gnl|CDD|179097	PRK00723, PRK00723, phosphatidylserine decarboxylase; Provisional.	1.87765e-95
NZ_CP036524.1|WP_006444407.1|234293_235511_+|2-iminoacetate-synthase-ThiH	gnl|CDD|236425	PRK09240, thiH, 2-iminoacetate synthase ThiH.	0
NZ_CP036524.1|WP_006444409.1|232852_233485_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF	gnl|CDD|236320	PRK08644, PRK08644, sulfur carrier protein ThiS adenylyltransferase ThiF.	1.75504e-111
NZ_CP036524.1|WP_006444423.1|214475_215675_+|glycine-C-acetyltransferase	gnl|CDD|235893	PRK06939, PRK06939, 2-amino-3-ketobutyrate coenzyme A ligase; Provisional.	0
NZ_CP036524.1|WP_006444410.1|232651_232849_+|sulfur-carrier-protein-ThiS	gnl|CDD|340451	cd00565, Ubl_ThiS, ubiquitin-like (Ubl) domain found in sulfur carrier protein ThiS. ThiS, also termed Thiamine biosynthesis protein (ThiaminS), is a sulfur carrier protein involved in thiamin biosynthesis in prokaryotes. It has the beta-grasp ubiquitin-like (Ubl) fold with low sequence similarity to ubiquitin (Ub), and is activated in an ATP-dependent manner by sulfurtransferases, similar to the activation mechanism of Ub-activating enzyme E1. ThiS has common evolutionary origin with Ub-related protein modifiers in eukaryotes, a beta-grasp fold as Ub, and is closely related to proteins MoaD and Urm1.	4.46515e-22

Protein sequences

>NZ_CP036524.1|WP_040435794.1|225155_227786_+|pyruvate,-phosphate-dikinase
MAKWVYMFTEGNATMRNLLGGKGSNLAEMTNLGLPVPQGFTITTEACTQYYEDGEKINDEIMAQIMESITKMEEITGKKFGDKENPLLVSVRSGARASMPGMMDTILNLGLNEEVVEVLANKSGNPRWAWDCYRRFIQMYSDVVMEVGKKYFEELIDKMKEEKGVTQDVDLTAEDLQVLAEQFKDEYKEKIGQDFPTDPKEQLMGAIKAVFRSWDNPRANVYRRDNDIPYSWGTAVNVQMMAFGNMGDTSGTGVAFTRDPATGEKKLMGEFLMNAQGEDVVAGVRTPQKIDQLQEVMPEVYDQFVGICHKLEDHYRDMQDMEFTIEDKKLYMLQTRNGKRTAQAALKIACDLVDEGMITEEKAVAMIDPRNLDTLLHPQFDAAAIKAATPIGKALGASPGAACGKVVFTADDAKNWAARGEKVILVRLETSPEDIEGMKAAQGILTVRGGMTSHAAVVARGMGTCCVSGCGDIAMDEANKKFTLAGKEFHEGDALSLDGSTGNIYDGLIPTVDATIAGEFGRIMGWADKYRTMKVRTNADTPGDARKARELGAEGIGLCRTEHMFFEGDRIDAFREMICSDTVEEREAALEKILPVQQGDFEGLFEALEGNPVTIRFLDPPLHEFVPTEEEDIKKLADAQGKTVDQIKTIIDSLHEFNPMMGHRGCRLAVTYPEIAKMQTKAVIRAAINVQKAHADWSVCPEIMIPLIGDIKEFKYVKKIVVETADAEIAAAGSDLKYEVGTMIEIPRACLTADDIAKEADFFCFGTNDLTQMTFGFSRDDAGKFLDAYYDAKIFENDPFAKLDQTGVGQLMEMAIAKGRPANDKLHVGICGEHGGDPSSVEFCNKLGLNYVSCSPFRVPIARLAAAQAAITAKNA
>NZ_CP036524.1|WP_006444417.1|223703_224873_-|alanine-dehydrogenase
MNVGILKDIKTGENRVIATPVEVAGLAADGHRVYVQKGAGAKAGFPDEKYAVEGAVLTDTAEEIYKSCDFIAKVKEFEPSEYGLLRENQIVFTCIHPAAHPEEVQALLKKKVIAFTAEDSHRFGSPNCEAAGKQGALMGLESMLTINGGKGKFVSGLGGALGMKVLILGGGTVGQAALSVLHALGAWVTVADISIGTLRRLQNEYRQSIDTVISSRENIKALLPSVDMVLNCVKWPKGSTEYLITREMVRSMEPGSVIVDISNDEQGALETFHETTHENPRYVEEGVVHYCVSNIPGAIANSTSVAYAASVLPHFRSILNNGVAEACARDGYLRRSLTTYKGYLTHEETSALQNRPWIRPEEILGIAGRELDFAPPATVSRSDNFIKLT
>NZ_CP036524.1|WP_006444418.1|222265_223666_-|transporter
METMGFISIIPAILAIVLSFATRNTVISLAIACITGTLLAGQGVFGFPTLLKESLGTTSFSWVMLLNTFIGILVAYFQKTGAIQGFSQKVHDRNLSRRGAQLMAWVLGIFIYFSDSFSPLFVGSVMRSITDKAKVSREKLAYIADSTSAPVSVLMPITGWAAYLMGLAVGVGCIVDEKDASALFLKAIPFNFYPIFAVIFVGVIASGIIKDFGPMKKAEKRAVEEGKVIRDGATPLIGKELTEMQAYPGLKPRVFLNFIFPVLMIISIAIGTYIAFSSAKTMEAFLMVVLFMTVSMMIQGIPFKEVMNTLTDGVKGALPAVMLLALAYSVNALSSQMGTANYIISLTEDLLTPHMLPAIIFLVSAVMAFATGSSWGTFAICMPIALPLAFSFTDGTLTLLVIASFAAVAGGGVFGDHCSPLSDTTVLSSTGAAADHIDHVKTQLPYALVCGGLALIAYLIVGFVFV
>NZ_CP036524.1|WP_006444419.1|220791_222189_+|aminopeptidase
MEKDNTWKTYSAEECVELEQINRSYKSCLDEGKTERECVKLAVKMLREHGYRDLKEFIDGQKTLGAGDKVYAVCMGKSIAAFHIGTEPLEKGMNILGAHIDSPRIDVKQNPLYENEELSYLDTHYYGGIKKYQWVTLPLALHGVVAKTDGSLVEIHIGDKEEDPVFAVTDLLVHLASKQMEKKANAVIEGEKLDLLFASRPLSSDGSLEKEEKDAVKANVLRILETTYGISEEDFVSAELEIVPAGNARDCGIDRSMIMAYGQDDRVCAFTSLFALLDVDKVEKTACCILVDKEEIGSVGATGMHSRFFENVVAEMTALTGGSSDLRVRRALQNSKMLSSDVSAAFDPMFAETFEKRSSAFFGKGLVFNKFTGSRGKSGSNDANAEYLAEIRRAMDRKHVAYQFAELGKVDAGGGGTIAYIMANYGMEVIDSGVAVLCMHAPWEITSKADVYEAYKGYKAFIEEM
>NZ_CP036524.1|WP_040435795.1|218632_220633_+|MBL-fold-metallo-hydrolase
MKYKKIWSCILTTACVVSLAACAAAPGNEGNGGKDGGSSKKAKKATGMTKKNNEEVYDLLDFDDKQEMEFAKKNLLAAPSELEIKDENGKTVWSQKAYSFLEDREAPDTVNPSLWRSTQMNHLYGLFEVTDGIYQVRGYDMTNITFIQGETGWIVFDPLISTECSKAALELVNEELGERPVVGIVMSHPHVDHYGGIKGIISEEEVAERRIPVIAPEGFEEHAVSENVYAGNAMGRRAGYQYGTMLESSETGAMAIGIGMGQSTGTISYIPPNDIIKATGDRRTIDGVEMEFQMTPGTEAPAEMNTWFPQKKALWMAENCTGTLHNLYTLRGAQVRDGNAWAEYIMEAVTLYGEEADVVFQAHNWPHWGNGVIRNYMKDTAAMYKFINDQTLMYINEGYTSDEIANMITLPERLEKNWYTRQYYGTVAHNSKAVYQRYMGWYDANPVNLNRLAPTDRAKKYMEYLGDADAVLQKAEEDYEKGEYQWVAEITNMIVFAEPDNERARSLCADALEQLGYQAESGTWRNAYLSGAKELREGTEADPDIKANVSPDLMKSMTPEMMLDYLGILLDANKAQDVNLRINLNFTDEDPYLLTVESGVVLYQKNAGALDADATLTLPRLGMFAILNDDKEQQKSVIRVEGDPEVLEKLTEHMVKFDFFFHIIEP
>NZ_CP036524.1|WP_006444422.1|215740_218296_-|helix-turn-helix-transcriptional-regulator
MTGQETPVFLNDKFTPNLLPEVCAPRQALLKKYMHAAQFRFIYVGAQAGSGKTVSSLLWLNSCERRTIWIGLDSYDNAPSVFYKQLATGLYSLQPDNNAMRAVLVDPDFSASPVEHTIQLIAEMEPQEEAFALVLDDLHLITNAEIIKSLPAVIKRLPFSFVTLILSRHIIPDEFSTLVRDPQSQIITSRQLRFTEAEILRYFESLGRTLTAEEANFVYLATDGWAIGINAMAKSGQLQDEGEGYDFARYFKTQLWDNWEQDLRDFCLATAVVDEFDPELANVLSGREDAASVMEHLSRTNSFLSLLHGNTYRYHHLFQDFLRERLVQERVDVGGLYKTAALYYRDHSDYTRALKFSLDSGDFKNIDTYLYLFLFENHRGSVADYAEFLRPFFEKDFPRHAYRESPVLHVLSAWYYYLTSRHREFAEHMDAIMLHLPKIAKTGSTFVEFSMLAFSVDYRTTIHKKIKQFSMFGRFVKKYTPEGLATSIASFTHNLPYMHRSNFDYSDLALPPDVLDDIDHTFAPLLGAEWVYIKPGIRTCFLYEQNRMEEAARMLRTTLDCLSDKNKTEGRICVIVLQHSILWQTGNMKEADTVLTGLSNLVATEAQFFVPNLKAYTAKLALLDGNAAAAREWLDNYFVVDMEHVELFRAFQHFTTARAYITLGEFAEARRYLLLLREYGENLNRPLDAAEAGVLLSVLDWIEGNKKEAARTLLAVLEDMQPYEFIRIIADEGAAVLPILKKAAALMEKEDYRGPLKRQFMSEVLLAAHAMSKCHKGIAAQLDSRRPVKLSKQQTLMLSLLSQGYKNAEISDITGLAIPTIKSHTSIAYHKLGVNNALDAVLKARELGFID
>NZ_CP036524.1|WP_006444423.1|214475_215675_+|glycine-C-acetyltransferase
MARKDDILSIYTKEVEGIKEAGLFKGEAPFVSPQGSRVTMEDGRELLCMCANNYLGLGNSPRLIEAAKKTYDDKGYGVASVRFICGTQDIHKKLEKKISDFLGTDDTILYSSCFDANGGLFETLLTADDAVISDELNHASIIDGVRLCKAKRFRYKNNDMEDLEAKLKEADEAGARVKLIATDGVFSMDGIICNLKGVCDLADKYNALVMVDDSHAVGFVGKTGRGTPEHCGVQGRVDIITGTLGKALGGASGGYTSGRREIIDLLRQRSRPYLFSNSLAPAIAGASIELFDMLDESTELRDHLEDVTAYYRKELVDNGFDIIPGTHPCVPVMLYDEKTAAEFAKRMMDKGVYVVAFSFPVVPKGKARIRTQVCASHTKEDIDFIVKCFKEVRSEMGLK
>NZ_CP036524.1|WP_006444424.1|213383_214448_+|L-threonine-3-dehydrogenase
MGDIKNDGMMWALVKEKPEEGLWMKRVPVPEVGPNDVKIKIHKTAICGTDVHIYQWNDWAQHTIPVGLTAGHEYVGEVVEVGGGVQGFHIGDLVSGEGHITCGKCRNCLEGHKENCKDAKGVGVNRNGAFAEYLVIPSSNVWPCNPAIPEEMYAIFDPFGNATHTALSYDVLGEDVLITGAGPIGIMAAAIVKFSGARHVVVTDLNQYRLDLAKKLGATRVVNLKEEKLTDVMKEIGMTEGFDVGLEMSGSQPGLSDMIHNMKHGGKIALLGLQRTDAVVDLETVIFNGLNLRGIYGRKVWDTWYKMSTMLQAGLDISDIITHHFDIKDYEKGFEAMISGQSGKVILDWAHVND
>NZ_CP036524.1|WP_149301996.1|211815_213081_-|serine/threonine-transporter-SstT
MKNIINKWNSISLVLRIICGLILGIILGLAVPQASGISILGQLFVGALKGVAPILVFFLVMSALCRMGKGQKTNMKFIVVLYLLGNLLSALVAVLASYVAPITLTLTEAAESDVAPPSGVIEVLTNLLMNVVANPVDSIVNANYIGILAWAVIFGIALKKASEGTKTALDNISEAVAQAVKWIISCAPFGIMGLIFATISTEGLGALLTYGRLIMVLVGSMAFVALVMNPLIVFLCTKTNPYPLVFKCLSRSFITAFFTRSSAANIPVNMELCEDMGLDEDTYSISIPLGATINMAGAAITISTMVLAAAHTMGISVDFPTAFILCVLSALSAAGASGVAGGSLLLIPMACSLFGISNDVAMQVVGVGFIVGVIQDSCETGLNSSTDVLYTACAELRDRRKHPENYTTDINIHAKKRKAEA
>NZ_CP036524.1|WP_040435906.1|211018_211729_+|pentapeptide-repeat-containing-protein
MLRKITEGELLNIIKDRRPGEQLDLHESLLEDMDLSGWDLHNINFNKSDIRNVNLDKANMAYLKADNAFFGGSSLRGTDLSGAYLHSADLRGCDMTGADIRGADMFASALEHTVLTDVKTDDKTKYFHLYCPEKGPFIGWKVCFGRRIVQLLVPEDARRISGTTNEVKCDKAKVLTIKSVDYRESYKEAHSYVDENFVYRAGEMVYAENFNPDRFLDSAGGIHIWLTREEAIAYLG
>NZ_CP036524.1|WP_006444414.1|228831_229560_+|phosphatase-PAP2-family-protein
MGTRCRIKNPILPKYAIFPLLACVTVNFMAYNGTEVLTRSWKHYDLTLPFDGMVPVIPWFVVIYLGCYLFWIANYILIARQGKEHCYRFVTADMMSRIVCAVIFLLLPTTNVRPELAGDGLWVMLLRMIYEIDRPTRLFPSFHCLVSWFCYIGIRGQKNVPKAYRMFSCLFAILICVSTQVTKQHYIVDAVGGILVAEGTYWIAFHTELYRTPKNLFDRLYRLCFERRRRPVEKRGNCGEQE
>NZ_CP036524.1|WP_006444413.1|229543_230578_+|flippase-like-domain-containing-protein
MGSKNKKIANMVFLLVVFALTLYSVFKGEDLRAVLRAIITVNPWYLLPGIAGVIIFIWGESIIIHYMFGTLKIRTKRWTCFLYSCVGFFFSAITPSASGGQPMQIYYMRKNKIPVPVSTLVLMIVTITYKSVLVAIGLFVAFFQRGFVHRYLEGILPIFYLGVALNVLCCIAMSILAFHPALAKWIMMKFLKILERIHILKHKPERTRRLAESMDQYNATALYLRTHGRVIVNVLIITFLQRFALFFVTWFVYKAFGLNGAHIYDVVMLQAVVSVSVDMLPLPGGMGISENLFLIIFKGIFTAGLLLPGMVLSRGIAYYVQLLLSAGMTLFAHLTIGQKAADKI
>NZ_CP036524.1|WP_006444412.1|230599_231268_+|CDP-alcohol-phosphatidyltransferase-family-protein
MIGIYNYTVVLTYVSLASSVFGMTQAIHGRFKTAILCLAISGLCDMFDGKIARTKKDRTDDEKAFGIQIDSLCDVVCFGAFPALICYLLGVRGPIGIAIIILYCINSVIRLAYFNVMEAKNALVTESGEKYYRGLPITSMAIVLPLVFMVQFFVPDWVFRICLHLALLIVGILFIGNFKLRKPKNGTLAVLVAVVGAAVLIMIIFTNYRISFHTGWPWFCRR
>NZ_CP036524.1|WP_006444411.1|231281_232163_+|phosphatidylserine-decarboxylase
MKYIDREGKVTSDDSGQDRLLRWMYTHRAGRAALRLLVRPGISRAGGWLLERNWSRCLIKPFVKHNDIDLSCFRKQKFTSYNDFFTRQIKSEFRPMEGGPDTLVSPCDGKLSVYPVLHNRDGAGEFCIKNTKYTVESLLRSAHLAKRYEGGYACVFRLTVDDYHRYCYIDDGEKSENRTIPGIFHTVNPAANDVIPIYKENTREYSLLKSRHFKTVLMMEVGALMVGRITNYHGACKVKRGQEKGRFEFGGSTVILLFQKGAADLDKRLIDNTAKGFETIVKMGERIGAAPVC
>NZ_CP036524.1|WP_006444410.1|232651_232849_+|sulfur-carrier-protein-ThiS
MMKVNGREQEYVPGTSVELLLRQMEYPEQKVAVERNGEVVPRKQYAQTVLEDGDTIEVVSFVGGG
>NZ_CP036524.1|WP_006444409.1|232852_233485_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF
MITEEEIQRALAERHSPEVRKKLAGARVAVAGLGGLGSNVAFALARIGVGHLHLIDFDKVDITNLNRQQYFIRHIGMYKTSALTEELMEINPYLELCPECVKVTEENLLSLFAQDDIVCEAFDDPEAKAVLVNGILEHYPDKFLVCASGMAGWGGNDTIRTRKVTERFYVCGDGVSEPSYGRGLMAPRAALCAAHQANLITQYIIEGQIE
>NZ_CP036524.1|WP_040435793.1|233497_234277_+|thiazole-synthase
MEHTTEDTFTLGGHTFTSRFILGSGKYSLDLIKAAVEHAGAQIITLALRRADEGGMANILDYIPEHVTLLPNTSGARNAEEAVRIARLSRELGCGDFVKVEVIRDSKYLLPDNYETVKATEILAREGFVVMPYMYPDLNAARDMARAGAACIMPLGSPIGSNKGICTRDFIQILIDEIDLPVIVDAGIGKPSQACEAMEMGAAAVMANTAIATAGDIPSMAGAFCKAVEAGRAAYLSGMGRVMDRGASASSPLTGFLQD
>NZ_CP036524.1|WP_006444407.1|234293_235511_+|2-iminoacetate-synthase-ThiH
MDEQTCVNESILNDDIREWQKKNRIDHMSYLPGMEVLKSDVEAQVTAAMNSYDYTKYTADDVRRALGHENRSPEDFAALLSPAALPLLEEVAQCARTETRKHFGNSVNMFTPVYIANYCENFCIYCGFNCHNKIRRAILSAEEIEREMEAVARSGLREALILTGESRKHSDVEYIAGACMTARKYFKVVGLEVYPMNSDEYAYLHKCGADYVTVFQETYNSDKYESLHLSGHKRIFPYRLNAQERALRGGMRGVGFAALLGLDDFRKDAFATGMHAYLLQRKYPHAEIAFSCPRLRPIINNDKIDPMDVHEPQLLQTVCAYRLFMPFASITISTRECARVRDHLVNIAATKISAGVSTAIGEHVGDTEAKGDGQFEISDMRSVEEVYNGLLGQKLQPVMQDYVYV
>NZ_CP036524.1|WP_006444406.1|235525_236110_+|thiamine-phosphate-synthase
MHDNMEMSRGGIIAVTNRHLCRRPYLEQVERICLRHPPALIVREKDLAEEAYERLICEVRDICDAYDVFCIPHTYMEAAERLRSCAVHLPLPLFRSCRDRALRFRWAGTSVHSVQEALEAEALGAAYMTAGHVFSTDCKRGVLPRGTGFLKGVCEAVNVPVYAIGGMQGTETCVREMSAFGASGICVMSECMRW
>NZ_CP036524.1|WP_006444405.1|236189_237116_+|cysteine-synthase-A
MIYDNVLEAVGDTPLIRLNRMTGPGDAEILVKFEAVNVGGSVKTRTALNMIETAEKKGLIHKDTVIVEPTSGNQGIGLALIGAVKGYKTVIIMPDSVSEERRKLVQNYGAEVRLIHDAGNIGDCIDECLRTALKMAEEDPDVYVPQQFENEANSAAHREQTGQEILRQAGKPIHGFCSGIGTGGTITGIGEALRAENPDMEIWAVEPENAAILSGGKVGTHLQMGIGDGVIPDILNQKIYDDIVIVTDEEALKTAKELAGKEGLMCGISSGTNVAAAVRMAKKLGRGKTVVTVLADTAERYFSTPLFQ

Crispr_ID: NZ_CP036524_2

• CRISPR_ID: NZ_CP036524_2
• CRISPR_location: 2483802-2484636
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 12 spacers

Consensus repeat of NZ_CP036524_2

Consensus_repeat	Method
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	CRT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	PILER-CR
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	CRISPRCasFinder

spacers of NZ_CP036524_2

>2.1|2483835|34|NZ_CP036524|CRT
TCATCGGTCTTGGAGCAAGACTGCAGGTGTTCCA
>2.2|2483902|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
CAGTTTTTCCTTTTAAACCTGTAAAATATTTAAC
>2.3|2483969|33|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
AGTAAAATCTAGGTCTTTCCTATGCCCGATGAT
>2.4|2484035|35|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
TCCGCTTCCACATGTAGCAAGTTATATACGGTTGC
>2.5|2484103|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
CTTGCTCTTCCCACGCCCTTTTTTAAAATTGTAT
>2.6|2484170|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
GGGAGATCCTCAGAAGTTTACGGAAATTTGTGGG
>2.7|2484237|35|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
AAGGCGGAACGTGAAGAAATAGCGGTTGAGGTGCC
>2.8|2484305|33|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
GAAACTCAGATCGCACGCTATAACGTAATCAAA
>2.9|2484371|33|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
GTAAATACAATGATTATCAGAGCGCGCTAAAAG
>2.10|2484437|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
GAAATTCACATTGTTGGACGATACAGGGGAATAT
>2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
TTTCGGGCAATTGGAAGAAGGCCTGGGGTGGTAT
>2.12|2484571|33|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder
GTTCCAGAACTTGGTCCATTTCCTCCCGGGTCA

CRISPR arrays and Neighbor proteins around NZ_CP036524_2

CRISPR arrays

The CRISPR arrays of NZ_CP036524_2

>merge|NZ_CP036524|2|2483802-2484636|CRT,PILER-CR,CRISPRCasFinder
GATGGTTTCAATTCCTTCCATGTGGAGGGAAACTCATCGGTCTTGGAGCAAGACTGCAGGTGTTCCAATTTCAATCCGCTCCTTCCATGCGGAAGGAGACCAGTTTTTCCTTTTAAACCTGTAAAATATTTAACATTTCAATCCACTCCTTCCATGCGGAAGGAGACAGTAAAATCTAGGTCTTTCCTATGCCCGATGATATTTCAATCCACTCCTTCCATGCGGAAGGAGACTCCGCTTCCACATGTAGCAAGTTATATACGGTTGCATTTCAATCCACTCCTTCCATGCGGAAGGAGACCTTGCTCTTCCCACGCCCTTTTTTAAAATTGTATATTTCAATCCACTCCTTCCATGCGGAAGGAGACGGGAGATCCTCAGAAGTTTACGGAAATTTGTGGGATTTCAATCCACTCCTTCCATGCGGAAGGAGACAAGGCGGAACGTGAAGAAATAGCGGTTGAGGTGCCATTTCAATCCACTCCTTCCATGCGGAAGGAGACGAAACTCAGATCGCACGCTATAACGTAATCAAAATTTCAATCCACTCCTTCCATGCGGAAGGAGACGTAAATACAATGATTATCAGAGCGCGCTAAAAGATTTCAATCCACTCCTTCCATGCGGAAGGAGACGAAATTCACATTGTTGGACGATACAGGGGAATATATTTCAATCCACTCCTTCCATGCGGAAGGAGACTTTCGGGCAATTGGAAGAAGGCCTGGGGTGGTATATTTCAATCCACTCCTTCCATGCGGAAGGAGACGTTCCAGAACTTGGTCCATTTCCTCCCGGGTCAATTTCAATCCACTCCTTCCATGCGGAAGGAGAC

>NZ_CP036524|2|2|2483802-2484636|CRT
GATGGTTTCAATTCCTTCCATGTGGAGGGAAAC	TCATCGGTCTTGGAGCAAGACTGCAGGTGTTCCA
ATTTCAATCCGCTCCTTCCATGCGGAAGGAGAC	CAGTTTTTCCTTTTAAACCTGTAAAATATTTAAC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	AGTAAAATCTAGGTCTTTCCTATGCCCGATGAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	TCCGCTTCCACATGTAGCAAGTTATATACGGTTGC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	CTTGCTCTTCCCACGCCCTTTTTTAAAATTGTAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GGGAGATCCTCAGAAGTTTACGGAAATTTGTGGG
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	AAGGCGGAACGTGAAGAAATAGCGGTTGAGGTGCC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GAAACTCAGATCGCACGCTATAACGTAATCAAA
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GTAAATACAATGATTATCAGAGCGCGCTAAAAG
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GAAATTCACATTGTTGGACGATACAGGGGAATAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	TTTCGGGCAATTGGAAGAAGGCCTGGGGTGGTAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GTTCCAGAACTTGGTCCATTTCCTCCCGGGTCA
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC

>NZ_CP036524|2|2|2483869-2484636|PILER-CR
ATTTCAATCCGCTCCTTCCATGCGGAAGGAGAC	CAGTTTTTCCTTTTAAACCTGTAAAATATTTAAC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	AGTAAAATCTAGGTCTTTCCTATGCCCGATGAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	TCCGCTTCCACATGTAGCAAGTTATATACGGTTGC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	CTTGCTCTTCCCACGCCCTTTTTTAAAATTGTAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GGGAGATCCTCAGAAGTTTACGGAAATTTGTGGG
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	AAGGCGGAACGTGAAGAAATAGCGGTTGAGGTGCC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GAAACTCAGATCGCACGCTATAACGTAATCAAA
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GTAAATACAATGATTATCAGAGCGCGCTAAAAG
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GAAATTCACATTGTTGGACGATACAGGGGAATAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	TTTCGGGCAATTGGAAGAAGGCCTGGGGTGGTAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GTTCCAGAACTTGGTCCATTTCCTCCCGGGTCA
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC

>NZ_CP036524|2|2|2483869-2484636|CRISPRCasFinder
ATTTCAATCCGCTCCTTCCATGCGGAAGGAGAC	CAGTTTTTCCTTTTAAACCTGTAAAATATTTAAC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	AGTAAAATCTAGGTCTTTCCTATGCCCGATGAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	TCCGCTTCCACATGTAGCAAGTTATATACGGTTGC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	CTTGCTCTTCCCACGCCCTTTTTTAAAATTGTAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GGGAGATCCTCAGAAGTTTACGGAAATTTGTGGG
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	AAGGCGGAACGTGAAGAAATAGCGGTTGAGGTGCC
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GAAACTCAGATCGCACGCTATAACGTAATCAAA
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GTAAATACAATGATTATCAGAGCGCGCTAAAAG
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GAAATTCACATTGTTGGACGATACAGGGGAATAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	TTTCGGGCAATTGGAAGAAGGCCTGGGGTGGTAT
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC	GTTCCAGAACTTGGTCCATTTCCTCCCGGGTCA
ATTTCAATCCACTCCTTCCATGCGGAAGGAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006442256.1|2498448_2499594_-|sporulation-integral-membrane-protein-YtvI	unknown	unknown	gnl|CDD|274334
NZ_CP036524.1|WP_006442240.1|2478418_2479414_+|asparaginase	unknown	unknown	gnl|CDD|199207
NZ_CP036524.1|WP_006442241.1|2479561_2480257_+|VanR-ABDEGLN-family-response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP036524.1|WP_040434743.1|2492867_2495048_-|alpha-galactosidase	unknown	unknown	gnl|CDD|307952
NZ_CP036524.1|WP_006442250.1|2487715_2490940_+|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl|CDD|235393
NZ_CP036524.1|WP_050765476.1|2481514_2482522_+|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl|CDD|224600
NZ_CP036524.1|WP_040435387.1|2476666_2477392_-|phosphatase	unknown	unknown	gnl|CDD|213992
NZ_CP036524.1|WP_006442258.1|2500228_2502562_-|endopeptidase-La	unknown	unknown	gnl|CDD|223542
NZ_CP036524.1|WP_006442257.1|2499597_2500200_-|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl|CDD|234770
NZ_CP036524.1|WP_006442249.1|2484868_2487565_-|NYN-domain-containing-protein	unknown	unknown	gnl|CDD|223556
NZ_CP036524.1|WP_040434741.1|2477868_2478345_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442255.1|2497074_2498403_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240548
NZ_CP036524.1|WP_006442254.1|2496132_2496960_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133409
NZ_CP036524.1|WP_040434740.1|2477616_2477832_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442235.1|2475675_2476287_+|DUF1836-domain-containing-protein	unknown	unknown	gnl|CDD|378076
NZ_CP036524.1|WP_147570440.1|2480381_2481389_+|GHKL-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP036524.1|WP_040434744.1|2495253_2496105_+|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380391
NZ_CP036524.1|WP_006442244.1|2482575_2483622_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|223787
NZ_CP036524.1|WP_006442236.1|2476308_2476602_-|TrpR-YerC/YecD	unknown	unknown	gnl|CDD|188231
NZ_CP036524.1|WP_147570441.1|2490987_2492850_-|amylosucrase	unknown	unknown	gnl|CDD|200463

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006442240.1|2478418_2479414_+|asparaginase	gnl|CDD|199207	cd08963, L-asparaginase_I, Type I (cytosolic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type I L-asparaginases, which are highly specific for asparagine and localized in the cytosol. Type I L-asparaginase acts as a dimer. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase. One example of an enzyme with no L-glutaminase activity is the type I L-asparaginase from Wolinella succinogenes.	7.82535e-155
NZ_CP036524.1|WP_006442241.1|2479561_2480257_+|VanR-ABDEGLN-family-response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.71162e-89
NZ_CP036524.1|WP_040434743.1|2492867_2495048_-|alpha-galactosidase	gnl|CDD|307952	pfam02065, Melibiase, Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.	3.89821e-177
NZ_CP036524.1|WP_006442250.1|2487715_2490940_+|carbamoyl-phosphate-synthase-large-subunit	gnl|CDD|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP036524.1|WP_050765476.1|2481514_2482522_+|D-alanyl-D-alanine-carboxypeptidase	gnl|CDD|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	5.1223e-55
NZ_CP036524.1|WP_040435387.1|2476666_2477392_-|phosphatase	gnl|CDD|213992	cd07437, PHP_HisPPase_Ycdx_like, Polymerase and Histidinol Phosphatase domain of Ycdx like. PHP Ycdx-like is a stand alone PHP domain similar to Ycdx E. coli protein with an unknown physiological role. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. It has also been shown that the PHP domain functions in DNA repair. The PHP structures have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel. YcdX may be involved in swarming.	1.20662e-130
NZ_CP036524.1|WP_006442258.1|2500228_2502562_-|endopeptidase-La	gnl|CDD|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP036524.1|WP_006442257.1|2499597_2500200_-|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl|CDD|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	3.03909e-99
NZ_CP036524.1|WP_006442249.1|2484868_2487565_-|NYN-domain-containing-protein	gnl|CDD|223556	COG0480, FusA, Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis].	1.93384e-132
NZ_CP036524.1|WP_006442256.1|2498448_2499594_-|sporulation-integral-membrane-protein-YtvI	gnl|CDD|274334	TIGR02872, UPF0118_membrane_protein_YtvI, sporulation integral membrane protein YtvI. Three lines of evidence show this protein to be involved in sporulation. First, it is under control of a sporulation-specific sigma factor, sigma-E. Second, mutation leads to a sporulation defect. Third, it if found in exactly those genomes whose bacteria are capable of sporulation, except for being absent in Clostridium acetobutylicum ATCC824. This protein has extensive hydrophobic regions and is likely an integral membrane protein. [Cellular processes, Sporulation and germination].	8.64828e-55
NZ_CP036524.1|WP_006442255.1|2497074_2498403_+|MATE-family-efflux-transporter	gnl|CDD|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	4.9357e-101
NZ_CP036524.1|WP_006442254.1|2496132_2496960_-|MerR-family-transcriptional-regulator	gnl|CDD|133409	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BltR (BmrR-like transporter) of Bacillus subtilis, and related proteins; N-terminal domain. Blt, like Bmr, is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. These regulators are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	9.71774e-41
NZ_CP036524.1|WP_006442235.1|2475675_2476287_+|DUF1836-domain-containing-protein	gnl|CDD|378076	pfam08876, DUF1836, Domain of unknown function (DUF1836). This family of proteins are functionally uncharacterized.	2.35128e-37
NZ_CP036524.1|WP_147570440.1|2480381_2481389_+|GHKL-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.35588e-44
NZ_CP036524.1|WP_040434744.1|2495253_2496105_+|AraC-family-transcriptional-regulator	gnl|CDD|380391	cd06986, cupin_MmsR-like_N, AraC/XylS family transcriptional regulators similar to MmsR, N-terminal cupin domain. This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included is MmsR, a bacterial transcriptional regulator thought to positively regulate the expression of the mmsAB operon. The mmsAB operon contains two structural genes involved in valine metabolism: mmsA which encodes methylmalonate-semialdehyde dehydrogenase, and mmsB which encodes 3-hydroxyisobutyrate dehydrogenase. The cupin domain of members of this subfamily does not contain a metal binding site.	4.3898e-31
NZ_CP036524.1|WP_006442244.1|2482575_2483622_+|ABC-transporter-substrate-binding-protein	gnl|CDD|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	1.14373e-47
NZ_CP036524.1|WP_006442236.1|2476308_2476602_-|TrpR-YerC/YecD	gnl|CDD|188231	TIGR02531, conserved_hypothetical_protein, TrpR-related protein YerC/YecD. This model represents a protein subfamily found mostly in the Firmicutes (Bacillus and allies). This family is similar in sequence to the trp operon repressor TrpR described by TIGR01321, and represents a distinct clade within the broader family described by pfam01371. At least one species, Xylella fastidiosa, in the Proteobacteria, has a member of both this family and TIGR01321. Several genomes with a member of this family do not synthesize tryptophan, and members of this family should not be considered trp operon repressors without new evidence. [Unknown function, General].	2.37678e-45
NZ_CP036524.1|WP_147570441.1|2490987_2492850_-|amylosucrase	gnl|CDD|200463	cd11324, AmyAc_Amylosucrase, Alpha amylase catalytic domain found in Amylosucrase. Amylosucrase is a glucosyltransferase that catalyzes the transfer of a D-glucopyranosyl moiety from sucrose onto an acceptor molecule. When the acceptor is another saccharide, only alpha-1,4 linkages are produced. Unlike most amylopolysaccharide synthases, it does not require any alpha-D-glucosyl nucleoside diphosphate substrate. In the presence of glycogen it catalyzes the transfer of a D-glucose moiety onto a glycogen branch, but in its absence, it hydrolyzes sucrose and synthesizes polymers, smaller maltosaccharides, and sucrose isoforms. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0

Protein sequences

>NZ_CP036524.1|WP_006442244.1|2482575_2483622_+|ABC-transporter-substrate-binding-protein
MKKRLLAVLLVAVMGMTMLAACSSSKEEKDTKDAAETAGETKEQKTVDVTLNEVAHSIFYAPMYIAIEEGYFKDEGINLDLVTGFGADKTMTAVLSGEADIGFMGSEASIYTYNEGANDYVVNFAQLTQRAGNFLVAREEMPDFKWEDLKGKLVLGGRKGGMPEMVFEYILRQNNLDPAKDVEIDQSIDFGSTAAAFSGGQGDFTVEFEPGATSLEKENEGYVVASLGTDSGYVPYTAFSAKKSYIDKNPEIIQGFTNALQKGMDYVQSHTPEEIASIIAPQFKETDLDTITTIVTRYYDQDTWKDNLVFEKKSFELLQDILEDANELDKRAPYDDLVTTDFADKAAK
>NZ_CP036524.1|WP_050765476.1|2481514_2482522_+|D-alanyl-D-alanine-carboxypeptidase
MNNRRYKKPLPGRKYKRRRRKRIRLFLSATAVTLILLCVFLSAKILSPLMLEKGNAAESPYGSSASPLTVDLKNLYSPSAVLVDLDTGKTIAGNNSDDTIYPASLTKIMTAILAVEKTENLDEIITLPYDFFQNLYAEEASMAGFEPGEAVCLRDLLYGILLPSGAECCLAFADKIAGSEEDFVKLMNKKAEALGMEHTQFCNSTGLHDDEHYSTVEDLALLLKYALGNDDFREAFTASRHSTRPSAQHPGGFTFYSTMFENMSSAKVTGGEILGGKTGYTKEAGLCLASLADVNGKEYILVTAKADGNHDTEQFHILDAVNVYNQIGASAQNSQ
>NZ_CP036524.1|WP_147570440.1|2480381_2481389_+|GHKL-domain-containing-protein
MSTRDEYLPDAGHYAVVRSPAWSELKPLLLILLICAAFLWLVSILASAHFYARTKVRRSITKTGRMLRAYMLQDKDTTEIFPKDYAELSVQMAEIKATMHRHEQLLKEEAARKNDLITYLAHDLKTPLTSVIGYLSLLDEAPDMPDGQKEKYVRITLDKARRLEKLTNEFFEITRYNLQQISLEKETIDLSYMLVQMTDEFYPLLTSRGNTAQLTVRENMTVYGDAVKLARVFNNILKNAIAYSYPNTPVEIWAENREDDIWIYFRNKGKTIPAQKLASIFEKFFRLDEARTTNAGGAGLGLAIAKEIVTLHGGNITVKSENELTTFCLVLPSCH
>NZ_CP036524.1|WP_006442241.1|2479561_2480257_+|VanR-ABDEGLN-family-response-regulator-transcription-factor
MAEKILIVDDEQEIADLVALYLQNENFTVFKHYNALDALDCIRSETPDLAILDVMMPDMDGLELCRNIREQYRYPVIMLTAKDGEIDKITGLTLGADDYITKPFLPLELVARVKAQLRRYKRYNTGAGPDEDVIVHSGLVINVRTHECTLNEKPLSLTPTEFSILHILCRKKGEVVSSEELFHEIWNDEYFTKSNNTITVHIRHLREKMGDSFEDPKYIKTVWGCGYKIEN
>NZ_CP036524.1|WP_006442240.1|2478418_2479414_+|asparaginase
MKKILMIATGGTIASKEGADGLTPAMTGEELASFVPGIEDKCELDILQLMNIDSTNMRPRQWVEIRDAIMERYGSYDGFVILHGTDTMAYTAAALSYLIQNTPKPVVITGSQKPMGNPYTDAKLNVYQSVLYALDDSSCNVSIVFNGKAVAGTRGRKQRTRSFDAFESMNFPLLAVIHDDRIVRQYSGPLPSEEELVTYTHLNDRVFVLKLTPEAKADIFELLNSRYDAIILETFGIGGIPEYDDSFEKAIFGWVDSGKTLAVTTQVPEEGCDLDVYKVGKKYSEHPGILQAGDMTTEAIVAKMMWILGQTGDRDEIRALFFKEINHDRTV
>NZ_CP036524.1|WP_040434741.1|2477868_2478345_+|hypothetical-protein
MADMNLVPVTGIVQNITSMRDNCCELLVSIRNSDGITNFVVGPDSYVINEVRLRPGMSVIAFYDANLAIPLIFPPQYRAVIIGRKNPNENMYAGYFDENLTSEDGSLQLNMTGTTDVVTSNGQRFNCDLGGRLLVVYYSASTRSIPAQTTPRRVIVLC
>NZ_CP036524.1|WP_040434740.1|2477616_2477832_+|hypothetical-protein
MKDKKDLENERLIDSYDYLSNAASSWDCTGLIPSEPISTGELESYEDLYHFLPPNGKASNLKPEEKDEQTK
>NZ_CP036524.1|WP_040435387.1|2476666_2477392_-|phosphatase
MNIAVDTHTHTLASGHAYNTLREMARMAADKGLSGLAVTEHAPEMPGTCHSFYFQNMRVIPRNMYGIELLMGVELNVMDENGSVDLPESLIRELDIAIASIHVPCYKDVLGRAEITQTYINVMEKDHIDIIGHPDDGRVPVDYEVLVKEAKRTGTLLEVNNSSLRPGGFRQDTRHNAACMLRLCKKYETMVVLGSDAHMDVDIANCRYSMEVVDEIGFPEELVANTSLEKLKACLKRNKKL
>NZ_CP036524.1|WP_006442236.1|2476308_2476602_-|TrpR-YerC/YecD
MSKKIRTEAVDYLFSAILSLDDKEECYTFFEDICTINELLSLSQRFEVAKMLREHKTYLEIAEKTGASTATISRVNRSLNYGNDGYDMVFERIKEDK
>NZ_CP036524.1|WP_006442235.1|2475675_2476287_+|DUF1836-domain-containing-protein
MTIDTKDMLNSILSSISRIDYVRPDSIPNIELYMDQVTTFMEKELSTTKRFPEDKILTKTMINNYAKNNLLPPPVKKKYSREHILVLIFIYYFKNILSIKDIETLLAPITEKYFDNDSSFDLTSIYEEICQTEKERIDSLQKEVARAHRTAAESFSQAPEDERDYLQLFSFICSLSFDVYVKKLLIEKLIDELPAPDTENKKK
>NZ_CP036524.1|WP_006442249.1|2484868_2487565_-|NYN-domain-containing-protein
MKRIVLGILAHVDAGKTTLSESMLYLSGAVRRMGRVDHKDAFLDTYEMEKERGITIFSKQAVFPLDGMEVTLMDTPGHVDFSAEMERTLQVLDYAVLVVSGADGVQGHTETLWRLLARYHIPTFVFINKMDQDGTEKERLLKELQDRLGGECVDFSPERDMEIFYEQIAMCDEALLEQYLAEERAGEEDIARLIRERKVFPCFFGSALKMAGVEELLRGIVQYTRQPVYSEVFGAKVYKIARDSQGSRLTYMKITGGSLRVKEVVEAGHRESGREPFREKADQIRIYSGAKYETVQKAEAGMVCAVTGLTGTYPGQGLGAESASDMPVLEPVLTYRLVLPDGTDAHTMLADLRLLEEEVPELHTVWKERLGEIHVNLMGEVQIGIIRRIIEERFGVAVQFDAGSIVYKETIRRAAEGVGHFEPLRHYAEVHLLMEPLESGSGLVFDSAVSEDELDGNWQRLILTHLEEREHPGVLTGSAITDMKITLIAGRGHLKHTEGGDFRQATYRAVRQGLKKAESILLEPYYTFRLEVPAESVGRAMSDLQRMNGSFEPPKMSGDMSVLEGSAPVASMRDYQTEVNAYTRGRGRLSCMQGGYRPCQNAEEIITAIGYDSEKDIENPTGSVFCAHGAGFVVSWDKVEEYMHVDSGWQGGSLEDETARPGDSPEKRPAELSGAPACSEKELEEIFVRTYGPVKRKRPSERRRTESSNISAAEYRPPKKKREQAEEYLLVDGYNIIFAWDELKELAKVNIMSARDKLMDIMSNYQGFRRMTLILVFDAYKVEGNPGSVSTYHNIYVVYTKEAETADQYIEKTVHEIGRKHNVTVATSDALEQVIILGQGGRRLSAEGLREEVELAMQEMRSEHLKESRSTRSYLFDNLPDELADYVEELRMGEDSSD
>NZ_CP036524.1|WP_006442250.1|2487715_2490940_+|carbamoyl-phosphate-synthase-large-subunit
MSKRTDIHKVLIIGSGPIIIGQACEFDYSGTQACKALRGLGYEIVLVNSNPATIMTDPETADVTYIEPLNVERLEQIIAKERPDALLPNLGGQSGLNLCSELAKAGVLEKYNVQVIGVQVDAIERGEDRIEFKKAMDSLGIEMAKSEVAYSVEEALAIADELGYPVVLRPAYTMGGAGGGLVYNKDELKTVCARGLQASLVGQVLVEESILGWEELELEIVRDSENNMITVCFIENIDPLGVHTGDSFCSAPMLTISEECQKRLQEQAYKIVESVQVIGGTNVQFAHDPVSDRIIVIEINPRTSRSSALASKATGFPIALVSAMLAAGLTLKDIPCGKYGTLDKYVPDGDYIVIKFARWAFEKFKGVENKLGTQMRAVGEVMSIGKTYKEAFQKAIRSLETGRYGLGYAADFNTKSKEQLLQMLITPSSERHFIMYEALRKGASVEEIHEITKVKTYFIEQMKELVEEEETLAASKGSLPSDELLVSAKKNGFSDKYLSQVLEVPEDSVRSRREELGVQEAWEGVHVSGTPDSAYYYSTYNAEDKNPVRSDRPKIMILGGGPNRIGQGIEFDYCCVHASLALKKLGFETIIVNCNPETVSTDYDTSDKLYFEPLTLEDVLSIYKKEKPLGVIAQFGGQTPLNLASELEKNGVRILGTSPSVIDLAEDRDLFREMMEKLDIPMPESGMATTVDEALAIAERIGYPVMVRPSYVLGGRGMEVVYDDESMVSYMNAAVGVTPDRPILIDRFLNHATECEADAISDGTHAFVPAVMEHIELAGVHSGDSACIIPSVHISDDNVQTIKEYTRKIAEEMHVKGLMNMQYAIENGKVYVLEANPRASRTVPLVSKVCNIRMVPLATDIITSEITGRPSPVPGLKEQVIPYYGVKEAVFPFNMFQEVDPILGPEMRSTGEVLGLSDHYGEAFYKAQEAAQSKLPLSGTVLISVNRKDKAEVVEIAESFAADGFHIVATGTTCDLIREAGIEAEKVKKLYEGRPNILDMITNGKIQLIVNSPVGKGSVHDDSYLRKAAIKAKIPYMTTIAAARATAKGIRYVKENGNGDVRSLQQLHSEITEK
>NZ_CP036524.1|WP_147570441.1|2490987_2492850_-|amylosucrase
MSKADDIFQRRMEKSHDELRWLYMELYGNDAMFAELTSQMYAYYRQRRIKLRNRDLKREEDPAWFKKNDMLGMMMYIDNFAGNLKGVKEKLSYLKSCNVNYLHLMPFLDSPRGRSDGGYAVSDFRKVKPDLGTMEDLADLADECHRKGISVCMDFVMNHTSEEHEWAKKARAGDGEYMSRYFFYDNYDIPRMYEATVPQVFPTTAPGNFTWLDDMGHFVLTSFYPYQWDLNYGNPRVFNEMMYNFLYLANQGMDIIRIDAVPYIWKQLGTQCRNLPQVHTIVRMMRIISEIVCPSVVLLGEVVMEPAKVAPYFGTVEKPECHMLYNVTTMATTWHSVAARDVRLLKQQMDIVNSLPKEYTFLNYLRCHDDVGWGLDYAALKQWGMEEVSHKKFLNDYFTGRIEGSRSRGELYNDDPVTKDARFCGTTASMCGIESAGFEHAAEKMEAAIRLDIMLHAYMLTQSGIPMLYSGDEIGQVNDYSYKEDAEKWSDSRYVHRGKFCWSLVENRGDSSTVQGKIFQTLDRLEAVRRQEEAFGPDADVYTYDVKDDAVLCILRQTKSSRFFGLFNFHDEERTAWMQEEGTYRDLMTGAVLELRDVPLPGHSFIWAKCIGDGLFLHKD
>NZ_CP036524.1|WP_040434743.1|2492867_2495048_-|alpha-galactosidase
MAIIYDDRKKTFTLNTESTTYQMQVDRYGFLLHLYYGKLAEGCMDYVLTYYDRGFSGNPYEAGKDRTYSLDALPQEFPCRGNGDFRAAALTVRNADGTYCCDMRYRSHVIVKGKYDLPGLPAVYGTEQEAQTLEITMEDSASGLQAVLLYGVLPELDIITRSVRIVNAGEKKVYIENIQSACLDLLSGNYDVISFYGRHAMERNFQRIPVPHGSFRIGSRRGTSSHQYSPFMILADKNATEDAGSCYAMNFVYSGGFSGEAEKDQFNQTRMMMGLQDELFSYPAAPGETFQAPEVILSYTDKGLNRLSQHMHRCIRTHVCRGKYRDAVRPVLVNSWEAAYFDFTGETIRKLAEDAKECGIDMVVMDDGWFGSRDGDFSGLGDWHVNEEKLGGTLRDLIRQINDMGIKFGIWIEPEMVNEDSDLYRAHPDWVLSVPGRKPVRARYQLVLDFSRKEVVDALFEQICKILDQGNIEYVKWDMNRSLSDVYSAGTEEQGRVLYDYVLGVYDFLERLTARYPDLLIEGCSGGGGRFDAGMMYYTPQIWCSDNTDAVDRVKIQYGSSFGYPVSAVGAHVSASPNHQTGRRTPMYTRTVTAMAGTFGYELNLGALSGEEKKEIRQQTDLYRKYAPLIQNGTYYRLSNPYEDEIGAWAFVSEDRRKVLLNAVTLDVHGNMTVNYIKPKGLKEDAVYEDMSSGQRYCGAALMEAGIPLPAAACEYEAYQIYLEEV
>NZ_CP036524.1|WP_040434744.1|2495253_2496105_+|AraC-family-transcriptional-regulator
MSNLLFSVFPNENFIDLGLYQYGWEQCSPSHSFGPAARNHFVFHYVISGTGRLMADSSDGNTRTFQIKSGQGFMLFPGQVNTYVADKELPWEYTWIEFDGLRAKEMVSLAGLTKDMPVYHAASKEMCRNMMDEMLYIARHSNETPFHLIGHLYLFLDCLTRSAASLKLRQGERIRDFYIKEALSFIEQNFQNDISVEDIAAFCGLNRSYFGKIFRDTLGKPPQEFLMSYRMAKAAELLKLTKLSVRDIGNAVGYPNQLHFSRAFKNIYGISPRDWRSQNGMSY
>NZ_CP036524.1|WP_006442254.1|2496132_2496960_-|MerR-family-transcriptional-regulator
MAIKKKESYLTTGEFARLTGVTKHTLFHYDAIGLLCPEVKLDNGYRYYTFSQLDIFEIIYTLKELNMPLQEIKEYVDGRTPESLLRLFKKESRIIEERMRKLRQMQRWMEEKTNCICAGIAASPEEISVRHEEKMYMVLSGIESSDEMGWSIEVGNFLDYCEEHGVRSSHGIGFRQNLSDIMAGSYDNYRTLYQLLRVKPKKVACEVRPEGEYVTAYHKGKWQDIGTAYRRLVDYATENGLKLSEHFYEDYLLDGLAVQQEEDFLTKIICMVSPD
>NZ_CP036524.1|WP_006442255.1|2497074_2498403_+|MATE-family-efflux-transporter
MSNSIAKDFKFFSLLRFAAPTIIMMVFMSLYTIVDGIFISRLLGTNALSSANIVYPVLNLVIAVGVMLASGGSAIIARKFGENKGQEAREDFSLLIIVGIAAGFVIMTAGNLFIEPIVRMLGATDLLLNDAVSYLGVSLFLAPACIMQLLFQTFFVTAGRPNLGLLLTIGGGLTNMVLDYVFMGPLQMGISGAALATGIGQLVPAVFGVFYFFFSKGSLHLTKPKFRGTVILESCLNGSSEMVTNISAAVVTYLFNIMMLRFLGEPGVAAITIVLYGQFLFNAMYMGFSMGVAPVISYNYGSGNQKLLRRIYRICISFICVSAVIITLFALLSSPYIVEIFTPAGTETYEIARGGFFLFSFNYLFAGINIFASAMFTAFSNGKISAIVSFVRTFVLIVANILLLPYLIGVNGIWLSVPAAECMTVLLSVYFFYKKRKDYHYI
>NZ_CP036524.1|WP_006442256.1|2498448_2499594_-|sporulation-integral-membrane-protein-YtvI
MRTDIKEKLHDDRPYWKVIVSLAFSLLGTVLFIFLGVRLLAFFMPFVIGWFIAFIASPVVNWLERRLKIVKKLGSAIIIIGVLAGLVFLLYFAGSRLWREIVSLVQNMPDLYKQLESGLSDIGKTLDGVFTILPKGIQNGWHAIVSNLDSTVGDLMGRISEPTVTAAGNFAKKIPSVLIATIVTVISAYFFIADREAVIAWSKKIAPDPVVRRMSMVIDNMKYAVGGYFKAQMKIMVVVFALLLVGFLLMGVHFQILLALLIAFLDFLPFFGTGTALIPWALYKFMVGNYRLAIALMALYAVTQLVRQLIQPKLVGDSMGLNPLVTLVLLYVGYKVGSVLGMIFAVPVGMIVINLFQAGAFDYILDDVKILLEGIMSLRNE
>NZ_CP036524.1|WP_006442257.1|2499597_2500200_-|YihA-family-ribosome-biogenesis-GTP-binding-protein
MIIRNINLETVCGITSILPDNDHPEIAFAGKSNVGKSSLINALMNRKSYARISATPGKTQTINFYNINNEMYLVDLPGYGYAKVSEKEKMKWGQLIERYLHGSGQLKAVFLLIDIRHEPSANDRMMYDWIVDQGYEPIIIATKLDKIKRSQVDKHIKMLRTGLDLIPGTKVIPFSSMTKQGRDEIWELVETEYLDRQEVE
>NZ_CP036524.1|WP_006442258.1|2500228_2502562_-|endopeptidase-La
MTNEVNSLPMVALRGMVVLPGMVTHFDVSREKSIEAIEQAMQENQKIFLTAQKDIEKENPGMNDICAVGCIASIKQIVKLPKKISRILVTGETRARMDCMEYDEPYLRANVVEVADIDNAEEAVGAKENPLNMEAMLRGLKDLFREYLPRNPKLSKDLALQMEEIKDLRRLVDEIAANIPLSWENAQELLEEPDVLKRYDKVVGRLVSEIQIINIKEEIQAKVKERVDKNQREYILREEMKIIREELGDDNTMSDADEFQEAADKLKAPAEVKEKLNKEIKRFKNTMGNPAETGVVRTYIETLLEMPWDNAGRDHKDIAYAKRVLDEDHYGLEKVKERVLEFLAVRALTKKGDTPILCLVGPPGTGKTSIAKSLARALKKPYVRISLGGVRDEAEIRGHRRTYVGAMPGRIATGLKSAGVKNPLMLLDEIDKVSNDYKGDTFSALLEVLDSEQNSKFRDHYIEVPVDLSEVLFVTTANTLQTIPRPLLDRMEVIEVSSYTENEKMHIAMEHLLPKQLRRHGLKPEQLTVSRRAVWKMARNYTKEAGVRQLERKLGEICRKAAREILETKKPAIHVTERNLHLYLGKELYTYQMANASDEVGIVRGLAWTSVGGDTLQIEVNIMPGEGEILLTGQLGDVMKESARTGISYIRSVSAAHKIEEMFFKEHDIHIHIPEGAVPKDGPSAGITMATAMISAVTERRVRADVAMTGEITLRGRVLPIGGLKEKLLAAKNAGIRTVIIPQENKVDLEDISSEIKKGMEILPVSHMDEVLKIALV

Crispr_ID: NZ_CP036524_3

• CRISPR_ID: NZ_CP036524_3
• CRISPR_location: 2658611-2659717
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 16 spacers
• Cas_protein_info: cas2,cas1,cas4,cas7,cas8c,cas5,cas3

Consensus repeat of NZ_CP036524_3

Consensus_repeat	Method
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CRISPRCasFinder
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CRT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	PILER-CR

spacers of NZ_CP036524_3

>3.1|2658644|34|NZ_CP036524|CRISPRCasFinder,CRT
CATATCTCACTAGTTTGATAAACACAAAGGTCAT
>3.2|2658711|35|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
AGCCTCTATGGATATGTAACGTGATGCTTTCAGAT
>3.3|2658779|36|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
GGCTCCATAGGTGGGGCTGTCGGTCATAGTATCTTC
>3.4|2658848|34|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
GTCTCGGATGCTCCTTTTTTCCTAATCCGGTTGT
>3.5|2658915|34|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
GGAACGCTGGAAAGAATCCATGTCTGAAGGAGTT
>3.6|2658982|36|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
AGAGGAAAAGCAGATATTTGAGCTTACATATCTCGT
>3.7|2659051|36|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
AAGAGCACAGTTAGCGTCAGTCAATGCATATGAGTT
>3.8|2659120|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
ACCAGTGAAGAGAGGGTGAGGCTGGCTTATTAT
>3.9|2659186|34|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
CGGTTAATTCAATGGGGTCACTACCTTCTGAGAA
>3.10|2659253|35|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
CAAGGGAATTACGCGAAGAACCAGGGTGAATATGC
>3.11|2659321|34|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
ACTACTGTGAGAGTGTATGGGACGTGGATCCGGT
>3.12|2659388|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
TTCCAACTAATGACTTAGATGATTTTGAGAATG
>3.13|2659454|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
AATGACTTGTTTTAATGGAACACAATTTTTGAT
>3.14|2659520|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
GGAAAAAATTTATTTAAGTGAAAGGGATATTAT
>3.15|2659586|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
TTATAACAGGTTTATTTCCGTCGTAATCCTTGT
>3.16|2659652|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR
ACAGGCTGCAATATTTATGAAGGCAGTATGATT

CRISPR arrays and Neighbor proteins around NZ_CP036524_3

CRISPR arrays

The CRISPR arrays of NZ_CP036524_3

>merge|NZ_CP036524|3|2658611-2659717|CRISPRCasFinder,CRT,PILER-CR
GCTTCTATCCATTTTATCCAGATGGATAGAGACCATATCTCACTAGTTTGATAAACACAAAGGTCATGCTTCAATCCACTCTACCCAAATGGGTAGAGACAGCCTCTATGGATATGTAACGTGATGCTTTCAGATGCTTCAATCCACTCTACCCAAATGGGTAGAGACGGCTCCATAGGTGGGGCTGTCGGTCATAGTATCTTCGCTTCAATCCACTCTACCCAAATGGGTAGAGACGTCTCGGATGCTCCTTTTTTCCTAATCCGGTTGTGCTTCAATCCACTCTACCCAAATGGGTAGAGACGGAACGCTGGAAAGAATCCATGTCTGAAGGAGTTGCTTCAATCCACTCTACCCAAATGGGTAGAGACAGAGGAAAAGCAGATATTTGAGCTTACATATCTCGTGCTTCAATCCACTCTACCCAAATGGGTAGAGACAAGAGCACAGTTAGCGTCAGTCAATGCATATGAGTTGCTTCAATCCACTCTACCCAAATGGGTAGAGACACCAGTGAAGAGAGGGTGAGGCTGGCTTATTATGCTTCAATCCACTCTACCCAAATGGGTAGAGACCGGTTAATTCAATGGGGTCACTACCTTCTGAGAAGCTTCAATCCACTCTACCCAAATGGGTAGAGACCAAGGGAATTACGCGAAGAACCAGGGTGAATATGCGCTTCAATCCACTCTACCCAAATGGGTAGAGACACTACTGTGAGAGTGTATGGGACGTGGATCCGGTGCTTCAATCCACTCTACCCAAATGGGTAGAGACTTCCAACTAATGACTTAGATGATTTTGAGAATGGCTTCAATCCACTCTACCCAAATGGGTAGAGACAATGACTTGTTTTAATGGAACACAATTTTTGATGCTTCAATCCACTCTACCCAAATGGGTAGAGACGGAAAAAATTTATTTAAGTGAAAGGGATATTATGCTTCAATCCACTCTACCCAAATGGGTAGAGACTTATAACAGGTTTATTTCCGTCGTAATCCTTGTGCTTCAATCCACTCTACCCAAATGGGTAGAGACACAGGCTGCAATATTTATGAAGGCAGTATGATTGCTTCAATCCACTCTACCCAAATGGGTAGAGAC

>NZ_CP036524|3|3|2658611-2659717|CRISPRCasFinder
GCTTCTATCCATTTTATCCAGATGGATAGAGAC	CATATCTCACTAGTTTGATAAACACAAAGGTCAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AGCCTCTATGGATATGTAACGTGATGCTTTCAGAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGCTCCATAGGTGGGGCTGTCGGTCATAGTATCTTC
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GTCTCGGATGCTCCTTTTTTCCTAATCCGGTTGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGAACGCTGGAAAGAATCCATGTCTGAAGGAGTT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AGAGGAAAAGCAGATATTTGAGCTTACATATCTCGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AAGAGCACAGTTAGCGTCAGTCAATGCATATGAGTT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACCAGTGAAGAGAGGGTGAGGCTGGCTTATTAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CGGTTAATTCAATGGGGTCACTACCTTCTGAGAA
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CAAGGGAATTACGCGAAGAACCAGGGTGAATATGC
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACTACTGTGAGAGTGTATGGGACGTGGATCCGGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	TTCCAACTAATGACTTAGATGATTTTGAGAATG
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AATGACTTGTTTTAATGGAACACAATTTTTGAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGAAAAAATTTATTTAAGTGAAAGGGATATTAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	TTATAACAGGTTTATTTCCGTCGTAATCCTTGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACAGGCTGCAATATTTATGAAGGCAGTATGATT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC

>NZ_CP036524|3|3|2658611-2659717|CRT
GCTTCTATCCATTTTATCCAGATGGATAGAGAC	CATATCTCACTAGTTTGATAAACACAAAGGTCAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AGCCTCTATGGATATGTAACGTGATGCTTTCAGAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGCTCCATAGGTGGGGCTGTCGGTCATAGTATCTTC
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GTCTCGGATGCTCCTTTTTTCCTAATCCGGTTGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGAACGCTGGAAAGAATCCATGTCTGAAGGAGTT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AGAGGAAAAGCAGATATTTGAGCTTACATATCTCGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AAGAGCACAGTTAGCGTCAGTCAATGCATATGAGTT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACCAGTGAAGAGAGGGTGAGGCTGGCTTATTAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CGGTTAATTCAATGGGGTCACTACCTTCTGAGAA
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CAAGGGAATTACGCGAAGAACCAGGGTGAATATGC
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACTACTGTGAGAGTGTATGGGACGTGGATCCGGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	TTCCAACTAATGACTTAGATGATTTTGAGAATG
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AATGACTTGTTTTAATGGAACACAATTTTTGAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGAAAAAATTTATTTAAGTGAAAGGGATATTAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	TTATAACAGGTTTATTTCCGTCGTAATCCTTGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACAGGCTGCAATATTTATGAAGGCAGTATGATT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC

>NZ_CP036524|3|3|2658678-2659717|PILER-CR
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AGCCTCTATGGATATGTAACGTGATGCTTTCAGAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGCTCCATAGGTGGGGCTGTCGGTCATAGTATCTTC
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GTCTCGGATGCTCCTTTTTTCCTAATCCGGTTGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGAACGCTGGAAAGAATCCATGTCTGAAGGAGTT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AGAGGAAAAGCAGATATTTGAGCTTACATATCTCGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AAGAGCACAGTTAGCGTCAGTCAATGCATATGAGTT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACCAGTGAAGAGAGGGTGAGGCTGGCTTATTAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CGGTTAATTCAATGGGGTCACTACCTTCTGAGAA
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	CAAGGGAATTACGCGAAGAACCAGGGTGAATATGC
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACTACTGTGAGAGTGTATGGGACGTGGATCCGGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	TTCCAACTAATGACTTAGATGATTTTGAGAATG
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	AATGACTTGTTTTAATGGAACACAATTTTTGAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	GGAAAAAATTTATTTAAGTGAAAGGGATATTAT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	TTATAACAGGTTTATTTCCGTCGTAATCCTTGT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC	ACAGGCTGCAATATTTATGAAGGCAGTATGATT
GCTTCAATCCACTCTACCCAAATGGGTAGAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006442405.1|2652823_2653555_+|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224651
NZ_CP036524.1|WP_040435412.1|2659972_2660263_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP036524.1|WP_006442422.1|2668161_2668833_-|DUF624-domain-containing-protein	unknown	unknown	gnl|CDD|227865
NZ_CP036524.1|WP_006442420.1|2664766_2665516_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP036524.1|WP_006442416.1|2660271_2661303_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NZ_CP036524.1|WP_006442409.1|2656190_2656520_-|SdpI-family-protein	unknown	unknown	gnl|CDD|379303
NZ_CP036524.1|WP_006442410.1|2656613_2656958_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442418.1|2661956_2662817_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl|CDD|187820
NZ_CP036524.1|WP_006442408.1|2655147_2655921_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP036524.1|WP_006442406.1|2653571_2654156_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP036524.1|WP_083790594.1|2658360_2658507_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl|CDD|377551
NZ_CP036524.1|WP_040434818.1|2661304_2661970_-|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl|CDD|187768
NZ_CP036524.1|WP_006442421.1|2665530_2667948_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NZ_CP036524.1|WP_006442412.1|2657554_2657899_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442411.1|2656987_2657515_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP036524.1|WP_006442403.1|2651108_2652578_-|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NZ_CP036524.1|WP_006442423.1|2668841_2669822_-|hypothetical-protein	unknown	unknown	gnl|CDD|225132
NZ_CP036524.1|WP_006442407.1|2654329_2655097_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP036524.1|WP_006442419.1|2662818_2664783_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP036524.1|WP_040435414.1|2669833_2670670_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|366542

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP036524.1|WP_006442421.1|2665530_2667948_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	4.1e-66	218.4	5.3
NZ_CP036524.1|WP_040434818.1|2661304_2661970_-|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	7e-38	125.0	0.5
NZ_CP036524.1|WP_040435412.1|2659972_2660263_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1e-29	97.3	1.6
NZ_CP036524.1|WP_006442420.1|2664766_2665516_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1.9e-62	205.4	0.0
NZ_CP036524.1|WP_006442416.1|2660271_2661303_-|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	1.6e-145	479.1	0.0
NZ_CP036524.1|WP_006442419.1|2662818_2664783_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	1.6e-137	454.1	3.2
NZ_CP036524.1|WP_006442418.1|2661956_2662817_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	2e-103	340.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006442405.1|2652823_2653555_+|MurR/RpiR-family-transcriptional-regulator	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.77115e-18
NZ_CP036524.1|WP_040435412.1|2659972_2660263_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.03691e-30
NZ_CP036524.1|WP_006442422.1|2668161_2668833_-|DUF624-domain-containing-protein	gnl|CDD|227865	COG5578, COG5578, Predicted integral membrane protein [Function unknown].	9.20782e-20
NZ_CP036524.1|WP_006442420.1|2664766_2665516_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	3.49905e-88
NZ_CP036524.1|WP_006442416.1|2660271_2661303_-|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP036524.1|WP_006442409.1|2656190_2656520_-|SdpI-family-protein	gnl|CDD|379303	pfam13630, SdpI, SdpI/YfhL protein family. This family of proteins includes the SdpI and YfhL proteins from B. subtilis. The SdpI protein is a multipass integral membrane protein that protects toxin-producing cells from being killed. Killing is mediated by the exported toxic protein SdpC an extracellular protein that induces the synthesis of an immunity protein.	7.42664e-09
NZ_CP036524.1|WP_006442418.1|2661956_2662817_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.65199e-116
NZ_CP036524.1|WP_006442408.1|2655147_2655921_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.18272e-55
NZ_CP036524.1|WP_006442406.1|2653571_2654156_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.7294e-10
NZ_CP036524.1|WP_083790594.1|2658360_2658507_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl|CDD|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	1.06023e-10
NZ_CP036524.1|WP_006442421.1|2665530_2667948_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.60177e-60
NZ_CP036524.1|WP_040434818.1|2661304_2661970_-|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.00953e-29
NZ_CP036524.1|WP_006442411.1|2656987_2657515_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	8.36822e-32
NZ_CP036524.1|WP_006442403.1|2651108_2652578_-|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.10958e-63
NZ_CP036524.1|WP_006442423.1|2668841_2669822_-|hypothetical-protein	gnl|CDD|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	8.02298e-56
NZ_CP036524.1|WP_006442407.1|2654329_2655097_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.90394e-59
NZ_CP036524.1|WP_006442419.1|2662818_2664783_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	7.66605e-142
NZ_CP036524.1|WP_040435414.1|2669833_2670670_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	4.09301e-29

Protein sequences

>NZ_CP036524.1|WP_083790594.1|2658360_2658507_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MGRVINGLAAIVQYNFKLDFFSNNLSLFCGRKYNRIKAFDWKGNRFLL
>NZ_CP036524.1|WP_006442412.1|2657554_2657899_-|hypothetical-protein
MNSLRNIFIAISIGIVVGIIFGGLKAIFRKKAPSQKQVEFMRRLLNKFAVVLKYSTITLLVIGLLWCTYFLLLGIIVPAQAEYADNMSELIVSVLTVISIIFAFVEFVRRKDDK
>NZ_CP036524.1|WP_006442411.1|2656987_2657515_-|GNAT-family-N-acetyltransferase
MDTPNLETERLILRKIHQDDINEIFNCWMQDEDVSRYMYWKASNDISDTKKFVEFELGKIADDKWNRWIIILKETSKIIGTCLIYFNEDENNWDISYNLGKKFWGKGYISEAMSTVMKYAKEVLKVKECIAIHATENLASGRIIKNLGFVYVKDVPYECSGGDIITTGRFYKCVF
>NZ_CP036524.1|WP_006442410.1|2656613_2656958_-|hypothetical-protein
MKKCRYCGKKLNIHIEFCCNECENNFRQLVEKDNRKIKYFILEIIVAFLVMLYGILSNSDFITGTGIILMGIVVVLLPFTTPDTIAFFGYRKSKFIGRILGMLLIVVGIWAGFS
>NZ_CP036524.1|WP_006442409.1|2656190_2656520_-|SdpI-family-protein
MIVLGKRWEKKPPADRNGLSGYRSTMSRLNQDTWSYAHKLWGKINFTTGIALAVLSFAFIVYIKDWSDFETWIVYLVFIQIAIMALTIIPTEIKLNKTFTKKGGRKQNG
>NZ_CP036524.1|WP_006442408.1|2655147_2655921_+|SDR-family-oxidoreductase
MFEDLKGKVVLLTGASMGLGRQQAIYFYKLGMKVSICARREEKLLEVVELCKETGADGEIMEVPCDISNYDQLKNYVDKTVERFGTIDFLVNNANKEALLMPLDEQPDDILKKDIFVGCMAHWRLMKLCVPYMKGKKASIINYASGNYQLGMDGMASYDADKGAIRGLAMVAARELGQYGIRVNTVGPAAVTDTVLNNTPPEYRDWVIRCSSCNSLRRVGLPETDIPPVVAWLMSETSGWVSGQNINIDGGSCIYGM
>NZ_CP036524.1|WP_006442407.1|2654329_2655097_+|SDR-family-oxidoreductase
MEKKLDNKVVLLTGASKGLGREMAVYLASEGAKLAICARTRDQLEETAKMCTDAGSEAVPVVCDVSDREQLRNFVSTAAEHFGRIDALINNAAYKYSNAPFLEQTEEDLLNAFSSGLFAVWDSMRLCFPYMKEKGGAIVNILSATYAEAIYGEASSNADKGGIRSLSMAAARDWGRHNIRVNTIAPDLRKTFYENVPEEFNDWVQTRETHFATAAGIEGNPKSVGAAAAFLISDDSQWITGQNITVDGGRCILFI
>NZ_CP036524.1|WP_006442406.1|2653571_2654156_-|TetR/AcrR-family-transcriptional-regulator
MKDDKRKRLSVELLKQALIELLQKKDMDRISIKELCETAGINRSTFYTYYDTQHELLEEIEDDILKELIVRFQNLSPETGLQEVIDSVRTCLRYVERNIDSFRALLGEHGDRAFSEKMIAANEAVIREWSSFGSADPDAEKTAYLFATCGGTSVIKNWIMDDDRMSAAQLSKLLGTLICKGYMGIFLSDPDKNM
>NZ_CP036524.1|WP_006442405.1|2652823_2653555_+|MurR/RpiR-family-transcriptional-regulator
MQYFNTDNLNEFEKRILETLNLECKKNKKLRIINAAELCGCSTSKISKTVKKLGFNNYKQYVNFINDEYIPEKPASNEFDRIRDFLDNFDLTMVDKFIELLDKHDKILLFGYGPSLFCAQYLEFKLRLFINKTVITITDEFSAASLIDEKTLLIIFSATGGFSSFDNLKKIAREKGGDLLLLIEEYNTSALSDDCQVLFLTDTFQTFTTVPYQKSRIVFFIFIEEVIQHIIKRNENNAVSSGK
>NZ_CP036524.1|WP_006442403.1|2651108_2652578_-|FAD-binding-oxidoreductase
MTKTELLEGLRGILEEDQINLDEEALYDAAADRYKKYAKAKKVLDVPIPMAIVYPDTTDEVKKILQFCNNNGVNVIPRSGKTATEGGLENWKECTVVVDANRMKKIIKIDTYNMQATVQAGVQLQTLEDELRKLGYTTGHSPQSKPVAEFGGLVATRSIGQFSTLYGGIEDMVAGLECVFPDGHISRIKNVSRRAGGPDIRHIVIGNEGTLCYITEVTVKIFKFYPENNKFYGYLVKDIDTGIKVLREVVVNGFKPSVARVYSEEDARQHFYHFHKGKCVLLFMAEGPAGIVEATGAEIEKAVEKYQSGIIEPVDASLIEEWFNHLNWSQQDLDDERQSMIDNDRHDGFTTEVSADWETIPKIYYNVIERIKKEFPRVDDLTMLGGHSSHSYINGTNMYFVYNYNINCNPEDEMRIYHHPLQRIIVEETLKEGGSMCHHHGIGKYRNEWTKEEHGSAYYMLEKLKEAFDPNGIMNFGTIFPQEEGKKYQ
>NZ_CP036524.1|WP_040435412.1|2659972_2660263_-|CRISPR-associated-endonuclease-Cas2
MLVLITYDVNTETEAGKRRLRKVAKQCVNYGQRVQNSVFECNLDAAKYRQVKAILEDIVDKSKDSLRFYNLGDKYKNKVEHIGAKKSFDVTDTLIF
>NZ_CP036524.1|WP_006442416.1|2660271_2661303_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYVTSTNRYLFLDGENVVILEDQEEIGRVPLHNLEGIVTFGYTGASPALMGACAERNIDLSFMSGNGRFLARVSGEVRGNVTLRKEQYRISEQKKESIKIARNFITGKVYNAKWVLERAARDYPLRLDVDRIKEKSAFMSGNLPKIRECEDAERLLGIEGESASLYFSVFDELILQQKDEFSFGGRNKRPPLDNVNAMLSFAYTLLTGMCASALESVGLDPYVGFYHTDRPGRVSLALDLMEELRSVMADRFVLTLINKKIIGASGFSKKESGAVIMDDDTRRQFLSHWQDKKKETITHPFLAEKMEWGLVPYVQAMLLARYIRGDLDEYPPFLWK
>NZ_CP036524.1|WP_040434818.1|2661304_2661970_-|CRISPR-associated-protein-Cas4
MILYNEEEYLQLSGIQHFAFCRRQWALAYIELQWSENVRTVEGKLLHEKAHDVTSEEKRGDLIISRAMPIHSRELGVSGECDIVEFHRSGTGITLSGRDGTYEAVPIEYKRGSPKQNDVDILQLTAQAMCLEEMLCCEIPYGYLYYGETRHRSKVVFEESIRQKVRDSFREMHQYYERRYTPRVKRTRSCNACSLKDFCLPVLGVGKSASSYIDKALSQED
>NZ_CP036524.1|WP_006442418.1|2661956_2662817_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSSLKGKIDFVAVVSATDANPNGDPLNGNRPRENYDGFGEISDVCIKRKIRNRFQDLGQKVFVQSDERSDDGFKSLKERADGCEELAKEIKNGKGADREACAEIACKEWLDVRAFGQVFAFKGNDVSLGIRGPVSIHQAVSCSPVDIISTQITKSVNSEPGKGGKASDTMGMKHRIGFGLYLIKGSVNVQLAEKTGFSQEDADILKESLKTLFENDASSARPEGSMEVCDLYWWQHEAKTPAVSSAKIHRSVKVEALNERPKSYADYKITLEPAEGCVKAEEYHFV
>NZ_CP036524.1|WP_006442419.1|2662818_2664783_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MNWTNELLDLYEKNQDIAGEVTYKTIKGKKGEEHIPLILLPVFHTTVTAQIEVTIDESGEFLSAKAVDKAENLTMIPVTEKSLSRTAGTEPHPLCDNLKYLAGDYMVYYRQGKKQKDYSENYRLYMEALQRWHESPFTHKKVDAIYAYVCKGCMIKDLATQGVMALDDEGKMTGDEKIQNVAQADAFVRFRVESILDAGADILADTSGQYCAECWLDKTLQEAYIQYYTSMLPEKDLCYLTGKREAISYLQPKKIRNEGDGAKLISANDESNFTFRGRFSDKTQAFAIGYETSQKIHNALKWIIRKQGYSWDGLYAVIWESGMNPLPTWSADTDTITDEYFNQKDWDEDELPESETGEVQASGFCSAMRGYGKKFGDTSRIVFLAFDAATTGRLAMTEYKTFESSRFLENLTYWYETCRWQQVKYKEGHKYDYLGMAGVNEIAEALYGTEQNGKLTLNNKRMYAQVCKRILPCISERRKIPVDMVRQAVQKASSPVVYEKRYNWEAVLGIACAMVKKERREQKKEDWNMALDKECKNRDYLYGRLLAVADRIERRTFDREEDAGRETNADRLMNAFSQHPYRTWQTIEQRIHPYLKKLDIRERNYYKKMLDEICEMFNIDSFADNSRLEGIYLLGYHSQLNEMRYQKTEEIKED
>NZ_CP036524.1|WP_006442420.1|2664766_2665516_-|type-I-C-CRISPR-associated-protein-Cas5
MKYRNTVEFQVEGAYALFADPITRVGGEKCSYHIPTYEALKGILHSIYWKPTLIWVIDAVRVLNPIQTETKGRKPINYNGGNDLSYYTYLKEVKYQVRAHFEWNENRPELTNDRNEHKHHNIAKRMIERGGRRDVFLGVRECQGYVSTCVFGEGKGYYDDVPGEIGYGFMYHGITYADEAVCEEDKGKMTARFWYPVMKQGVIEFVRPEECAEKRHLKEMEMKSFGEDMHNFTGLKEFEGEEGACELDK
>NZ_CP036524.1|WP_006442421.1|2665530_2667948_-|CRISPR-associated-helicase/endonuclease-Cas3
MEDPYIAHFREENGQITVQSVLEHNSNVAFLAEQNSSIEILSPIAGLIGTYHDAGKYLDAFQQYIEKNIEGKKTHRGEVNHSTAGGCLLEQFAAGTMETQMMEFPVYCHHGLSDALSGNGKILIDERLRQRENVQCVSERFYQFHDKQELENKFYESRKKIGEILTALHKYAQSLTQGERSLQKNFFVGMYERILLSLLIDADWSDTACFMENKKIEERIQKNHGRNRIWDECKRYFDVYMSRFSKDSKLSGMRTEILRQCLLQGKTDGTLYRLTVPTGSGKTLSSLGFALNHARVHHKKHIIYVAPYTSILEQNAEEIRKATGNPEIVLEHHSNIFYEGEEEQRRKELLAENWSSPIIVTTAVQFLNTLFSSSSKNIRRMNNICNSVIIFDEIQALPVRTIKLFNLAVNFLTGFGESTVVLCSATQPLLDRIMECSLNRPQNMIEPDKKYEDAFQRTTIHDKTKLTNLGLSAEELGEFILDRAQEEERVLAIVNTKKCAEATYKYLKKKCKDSDYLLFHLSTNMCPQNRQDVLNEIKEKLFEADRKIICVTTQLIEAGVDISFRCVIRSLAGLDSIVQAAGRCNRNKEVENGNVYVIKMSKEAENVSGLRDIVKAQEAMLSVLYQFEMRPSSFNDRLDSGKAIELYYSLYMSSRKEEMSYLVSADGRSDTLLNLLSTNSKVWSAVKRNNKDGHTFLRQAFKTAGDLFEVIPEDGKVDVVVEYDTAAKEQIRILCGQYVTLDEQQQAVRKLQKYTVGISDRMRQQLSNAVTTVCDDKRKILVLSENYYSHETGVSIEPVMEFINY
>NZ_CP036524.1|WP_006442422.1|2668161_2668833_-|DUF624-domain-containing-protein
MKARTGAYSYCTFPGLQAEVLILGNNIIIRILTRIFDLMILNILWLVCSVGIITIGASTTALYSVMLKIVRNEEGYIVRDFFKAFRENFRQSTVIWMVLLAVGMLLLADTAILHRMQGGAGLIGTMVFYIIVFFYFMEIIFVFPLIAKFENTTGSMIKNAILIPASRLPYAVMVLVMTGACVLLTFLDHRTIIAGIGIWSVIGAALLSYVNCFLIMKIFEPYL
>NZ_CP036524.1|WP_006442423.1|2668841_2669822_-|hypothetical-protein
MEIRKIIETIVKDREACGGIKNVVWLAAGGSNGGNYPAQYFMDREAKGIRSQMFTSNEFVYAPPKFVGENTIAVVTSMRGTPETCVAAKVAKELGAATIGLYVQESLLTETCDYNVKYDSIMFDESDQSKTNAALGMRIAMDIVDVTEGYEHYKDAMAAYDILDKVYNDAKAYCMPLAEKWAEQNKEEHTISVMASGPAYAAGYIFSICNIMEMLQIQSPTINCCEFFHGPFEVLDKNESFFLLVSEGRTRKADERAVKFLREYGGDKIYILDAKELGINRFKDSVAEYFNHMLFSPILNNTYMKKLSAATKIDYLTRRYMWKVQY
>NZ_CP036524.1|WP_040435414.1|2669833_2670670_-|sugar-phosphate-isomerase/epimerase
MKHLKESQILTSNYPYYKYSLDYSLKSLQRMGAGPIEFYACYPHFHLDDVSYWDVKRITKKLADAGLNVVCFTPEQCMYPVNIAALDVNARKRSLDIFKKSIRYGAEMGAEFVVTLAGYGTLDEEESCAWRRSAESLGILGDLAESCGVKLVLETSPREYTTTHNSKDVVRMIHETGSSAVKGMIDTATLGFSGETMEQAVEDLEGQLAHVHVADGIPNGHLVLGEGRLDIQHMLKKLDDAAYKGPLSLEILNDKYIRTPHEAMETSFKRLKEYINNC

Crispr_ID: NZ_CP036524_4

• CRISPR_ID: NZ_CP036524_4
• CRISPR_location: 3047228-3047415
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP036524_4

Consensus_repeat	Method
TTAAACGCAGAGTACCCAATGGATTGCAGACTCTCTGGAAAGGACACGC	PILER-CR

spacers of NZ_CP036524_4

>4.1|3047278|39|NZ_CP036524|PILER-CR
TTGCGGGAAAGAAGGGCTGGCAAGCCTTTTGCAGCCTTC
>4.2|3047367|20|NZ_CP036524|PILER-CR
TTTTAAGGCTCCCGCAGTCC

CRISPR arrays and Neighbor proteins around NZ_CP036524_4

CRISPR arrays

The CRISPR arrays of NZ_CP036524_4

>merge|NZ_CP036524|4|3047228-3047415|PILER-CR
CTTAAACGCATTGATTCCAATGGATTGCAGACTTTGCGGGAAAGAAGGGCTGGCAAGCCTTTTGCAGCCTTCAAACGCAGAGTCCCCAATGGATTGCAGACTCTCTGGAAAGGACACGCTTTTAAGGCTCCCGCAGTCCTTAAACACAGAGTACTCAATGGATTGCAGACTGTCTGGAAAGGACACGC

>NZ_CP036524|4|4|3047228-3047415|PILER-CR
CTTAAACGCATTGATTCCAATGGATTGCAGACTTTGCGGGAAAGAAGGGC	TGGCAAGCCTTTTGCAGCCTTCAAACGCAGAGTCCCCAA
TGGATTGCAGACTCTCTGGAAAGGACACGCTTTTAAGGCTCCCGCAGTCC	TTAAACACAGAGTACTCAAT
GGATTGCAGACTGTCTGGAAAGGACACGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_147570472.1|3037517_3038111_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP036524.1|WP_170254069.1|3047912_3048260_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442830.1|3057024_3057747_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP036524.1|WP_040434918.1|3042555_3043620_-|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl|CDD|379113
NZ_CP036524.1|WP_006442808.1|3036356_3037283_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270371
NZ_CP036524.1|WP_006442827.1|3053805_3054069_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_040434923.1|3052805_3053495_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP036524.1|WP_006442829.1|3055516_3057028_-|hypothetical-protein	unknown	unknown	gnl|CDD|224280
NZ_CP036524.1|WP_040434926.1|3054135_3055554_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223650
NZ_CP036524.1|WP_006442813.1|3040001_3040886_-|YitT-family-protein	unknown	unknown	gnl|CDD|224203
NZ_CP036524.1|WP_040434928.1|3058238_3058829_+|DUF1700-domain-containing-protein	unknown	unknown	gnl|CDD|227053
NZ_CP036524.1|WP_050765540.1|3045032_3045551_-|transcription-repressor-NadR	unknown	unknown	gnl|CDD|224740
NZ_CP036524.1|WP_006442810.1|3038110_3038875_+|nucleoside-phosphorylase	unknown	unknown	gnl|CDD|350158
NZ_CP036524.1|WP_006442831.1|3057925_3058246_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP036524.1|WP_006442812.1|3039439_3039898_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_040434920.1|3043896_3044991_+|KamA-family-radical-SAM-protein	unknown	unknown	gnl|CDD|224426
NZ_CP036524.1|WP_167534345.1|3048556_3050167_-|chitobiase/beta-hexosaminidase-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379107
NZ_CP036524.1|WP_006442811.1|3038927_3039437_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP036524.1|WP_006442824.1|3050051_3052691_-|leucine-rich-repeat-protein	unknown	unknown	gnl|CDD|275383
NZ_CP036524.1|WP_006442815.1|3041832_3042357_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl|CDD|376827

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_147570472.1|3037517_3038111_+|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.86411e-12
NZ_CP036524.1|WP_006442830.1|3057024_3057747_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.4417e-115
NZ_CP036524.1|WP_040434918.1|3042555_3043620_-|PTS-sugar-transporter-subunit-IIC	gnl|CDD|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	2.3369e-89
NZ_CP036524.1|WP_040434923.1|3052805_3053495_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.21137e-58
NZ_CP036524.1|WP_006442829.1|3055516_3057028_-|hypothetical-protein	gnl|CDD|224280	COG1361, COG1361, S-layer domain [Cell envelope biogenesis, outer membrane].	0.000175309
NZ_CP036524.1|WP_040434926.1|3054135_3055554_-|ABC-transporter-permease	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.46599e-30
NZ_CP036524.1|WP_006442813.1|3040001_3040886_-|YitT-family-protein	gnl|CDD|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	1.15046e-46
NZ_CP036524.1|WP_040434928.1|3058238_3058829_+|DUF1700-domain-containing-protein	gnl|CDD|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	4.82014e-21
NZ_CP036524.1|WP_050765540.1|3045032_3045551_-|transcription-repressor-NadR	gnl|CDD|224740	COG1827, COG1827, Predicted small molecule binding protein (contains 3H domain) [General function prediction only].	1.59349e-44
NZ_CP036524.1|WP_006442810.1|3038110_3038875_+|nucleoside-phosphorylase	gnl|CDD|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.81781e-98
NZ_CP036524.1|WP_006442831.1|3057925_3058246_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.75115e-18
NZ_CP036524.1|WP_006442808.1|3036356_3037283_-|substrate-binding-domain-containing-protein	gnl|CDD|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.50354e-35
NZ_CP036524.1|WP_040434920.1|3043896_3044991_+|KamA-family-radical-SAM-protein	gnl|CDD|224426	COG1509, KamA, Lysine 2,3-aminomutase [Amino acid transport and metabolism].	1.84999e-111
NZ_CP036524.1|WP_006442815.1|3041832_3042357_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl|CDD|376827	pfam02572, CobA_CobO_BtuR, ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin adenosyltransferase, EC:2.5.1.17, involved in cobalamin (vitamin B12) biosynthesis. These enzymes catalyze the adenosylation reaction: ATP + cob(I)alamin + H2O <=> phosphate + diphosphate + adenosylcobalamin.	2.2721e-72
NZ_CP036524.1|WP_006442811.1|3038927_3039437_-|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.46465e-17
NZ_CP036524.1|WP_006442824.1|3050051_3052691_-|leucine-rich-repeat-protein	gnl|CDD|275383	sd00036, LRR_3, leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	2.0492e-27
NZ_CP036524.1|WP_167534345.1|3048556_3050167_-|chitobiase/beta-hexosaminidase-C-terminal-domain-containing-protein	gnl|CDD|379107	pfam13290, CHB_HEX_C_1, Chitobiase/beta-hexosaminidase C-terminal domain.	3.22368e-19

Protein sequences

>NZ_CP036524.1|WP_050765540.1|3045032_3045551_-|transcription-repressor-NadR
MDGEKRREEIMKLLETEKEPLSGTALARRLGVSRQIIVQDIALLRATNKNILSTNKGYILYGKDSAAATCKRVVMVKHDNDKMAGELYCIVDAGARVLDVIVEHEVYGQIAVDLVINSRKDVDEFMAKILSDNARPLKELTGNVHYHTIEASDSEILDEAEKRLKEAGVLAD
>NZ_CP036524.1|WP_040434920.1|3043896_3044991_+|KamA-family-radical-SAM-protein
MNWQDELRHNITTLDELAAYIPGIDTGDCNARNILEKYPMSVPRYYLSLINTDDEGDCIRKMSIPSFSEMDITGTFDTSGESSNTKLRGLQHKYPQTVLLLSTNRCAMYCRYCFRKRMVGSHTEEIVEDIDKAVSYIAEHTEISNVLISGGDSFLLDNAAIEHYLSALCSIGHIDYIRFGTKVPVVFPQRITDDRELQDILKKYCTKKQLYVMTQFNHPSELTEHAVNAVNCLKSLGLIVKNQTVLLKGINDDPAVLAGLMKQFTKIGILPYYVFQCRPVTGVKNQFQVPLRTGYDIVEQAKRLQNGNGKCFRYALSNPDGKVEIIGKMDDSHMIFKYHQAKNPDNIGRIFIKEISEDACWAEE
>NZ_CP036524.1|WP_040434918.1|3042555_3043620_-|PTS-sugar-transporter-subunit-IIC
MEKLKKVLDRIFIDGLSAMAQGLFATLIIGTIIQQIGTLIGGPAGDMIYALGKVAASLTGAGIGAAVAYRFKESPLVVVSAATAGMVGAFAGKLLAGAVLVDGAMVYAGPGEPLGAFVAAYIGIVFGHLVSGKTKVDILVTPIVSIGTGSAVGLLLGPPISGFMAWLGSLINWGTEQQPFLMGIVVSVLMGMILTLPISSAALGIILNLSGLAAGAATVGCCCNMVGFAVASYRENKIGGLLAQGIGTSMLQVPNIVRRPVIWLPAILSSAILGPVGTMALHMTSNATGSGMGTAGLVGQIMTWQTMIQTEAASIVMIKILLIQIILPAVVTLVISEFMRKRQWIRFGDMKLEL
>NZ_CP036524.1|WP_006442815.1|3041832_3042357_-|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MTGTGRIHIYYGNGKGKTTAAVGQAVRAAGFGLKVLVFQFLKNNSSSERNVLEKTENITCLPGREHVKFVSQMNGDEKAELRHYNTKALDEIVKFCSPFDVLILDEILCAVQLGVLSEEKLIRFLEHKPRGLEIVMTGHEVSERMLELADYATEMRKVKHPYDEGKMARGGIEY
>NZ_CP036524.1|WP_006442813.1|3040001_3040886_-|YitT-family-protein
MGRFKENKKDLLIQAVYAVMGSLLFALGVNLIIVPLGLYNGGFMGIAQLLRTFFVEVCRLPVPSGIDMSGVIYFIINIPLFYMGLRVLGKEFAVKTLITVTIQSIFLVVVPIPAAPIIDDFLTSCIIGGLIAGTGTGLVLRGRSSGGGQDIIGLCCAKKYPNFSVGRINIMMNVLVYVICLFMFNIEIVIYSLIYTTVLAMALDRVHIQNINTSVMIFTKKLGISKAIIEQTGRGVTNWDGEGAYTNKTSYILFVMISKYEVGQIKRIVHSIDPDAFMIFTEGCAVKGNFEKRL
>NZ_CP036524.1|WP_006442812.1|3039439_3039898_-|hypothetical-protein
MRKRAIRFVSVLILFYSVCCMLWGGARILSVISAVSEEGGMFREVLRYLLYFLKGAVGLVTGVYGIKSVREVWRSSFTVYAAVTAAVFEAAVMILYGFKLYSILYTGLLVLLIVLIRSGEDKEKETAEETDKSADGLFAAKQAMSRNRCERR
>NZ_CP036524.1|WP_006442811.1|3038927_3039437_-|GNAT-family-N-acetyltransferase
MVKITYRRAMESDAEKIVAFYNYVGGETSYLSFEKDEYPMDVKAQAESIRGLEDNMTNIMLLAMDGEEIVGIATISSSHKIKARHDGELGIVVAKKYQGQGVGTELIRQLTEWAKGNGITRRISLDTRADNVKAVELYMKFGFIVEGCRRNATLLDGKYYDLYVMGMMI
>NZ_CP036524.1|WP_006442810.1|3038110_3038875_+|nucleoside-phosphorylase
MKTVFYESRTSAPALFDPSDTTKQAENFPEVCISTFSRQIIDRFAALDHVKVIADLYSANGINPVYKLSYGGREIAFYLSLVGAPAAVCGLEEVIALGGRKFVFFGSCGILDDEKVNGRLIVPSAAVREEGTSYHYLAPAAEIEPAAEETKLLKNCLENCGYPYVSGKIWTSDAIYRETTDAIQYYRELGCLGVDMEYSALLAAAAYRNVPFIQFFYGADSLAGGKWQPRDLTDYGLSNSEKYMALALECGLAM
>NZ_CP036524.1|WP_147570472.1|3037517_3038111_+|TetR-family-transcriptional-regulator
MSIKGDKTKMYICSEAYKLFAEKGFKEVTMQDICRKTDLSRGGLYRHYENTAQIFSAVISGMMAEQEDEFSEKIHSSMPAAQILDDVLNRYEEEMLDSGNSLSVAIYEYFSSPGISQYDDSILQQYLYSKKMWTELITYGMRTGEFKIVDPAAVFDLIVFSYQGVRMYSRLMPVHRDIPRGITGQIRNLLLSESEIR
>NZ_CP036524.1|WP_006442808.1|3036356_3037283_-|substrate-binding-domain-containing-protein
MKMKKFIAVLAVVGMIAGLAAGCGSSDEKADSNKDSGNETEASSDWDSASDITIVSREDGSGTRGAFIELFGIEEEKDGEKVDMTTEEAQITNSTSVMLTTVSGDDYAIGYVSLGSLDDSVKALKIDGAEATAENVKSGDYKVSRPFNIATKEGLDNEVASDFINFILSEEGQKVVEENGYIALDDVKPFEGTSPSGKAVAGGSSSVSPVMEKLIEAYNAVNANAEIELQTTDSTTGMTSAVDGSYDIGMASRELKDTEISKGLNAQVIATDGIAVIVNNNSTVDELSSDQVKSIYTGEALTWDEVIE
>NZ_CP036524.1|WP_170254069.1|3047912_3048260_-|hypothetical-protein
MKKKKKPCSLRITKRFLCAVMTAVLVCQLFSLPALAQDAPAPITVDPLPQGADVIAVPLGTAKEAIPFPELTADGGKVTLDSPAWRCEAYDPDKPGNYVFKAKLSEEYTGGGGIW
>NZ_CP036524.1|WP_167534345.1|3048556_3050167_-|chitobiase/beta-hexosaminidase-C-terminal-domain-containing-protein
MTVALPQGYQFTGGALGNLKLFTVNRQLEPPSITAASYDTAVPVVGGAVTVTPGTYTANEAGAEGEHRYTWYRSDRETGLGTPIARTKDYTPTGEDFGKYIWVETTPRGEITNFGGRPVASPRLQVGVKLTVAVTGSAGGTSPTIDGTAAGGGVVIYGPVTVSFTKTAAGDTVKWTASPNEGSFDDDTAATAVYTPAAQPSAGTIALTATLTVNAKDQDQPAPAPFELAYTANGETDYTVTIPEIAGAEYSFDGTTFGAERSKTGCKPGETVTGYARLAAKPGYNAGAVTGANVTLPLLDVHTPTISPSGGTFTGAQSVTLSCTTAGADIYYTLDGNTPNAGSTRYTGTFTLTKTATVKAIAVKAGMADSIVASASFTRATDDLTPVDLTKDATFTLNGDFALIGRVLLDGKEMGQVNKTPTSADLTWAGYPGNAGKLEKGSVIVTLYKEFLKTLPEGRYTLTVEFNDAGGSVSTGDLQFAVPKQQEPKPTATGGGSAKTGGGSAKTGDESNMALWIVLVCVAGFAVYRKRKYRNQ
>NZ_CP036524.1|WP_006442824.1|3050051_3052691_-|leucine-rich-repeat-protein
MKKKYRITKRFVSLLVVLALVVTLVPAAVLAQDAPTMESAAVTVDAISEGMDVIPVPFGTMQDAIPFPLLTAGGVSLDSVTWEAETYDAQQPGGYVFTAALPEGYMPPDGQADISVTVTVAEPQGTAGETIQANDETPSPVPEETVTGQPSQPPNGIAPSAPETAPVVVSAFDEIEPAAYEIAVGGGLPALPEMLKAADADGETIAIEGVIWEADNFDANTPGEYVFTAKLPEGYAAAPEAEAPQITVTVTEPPLAVSAFGAEETVTVISVYLGDDKWDNPVYYDVDEIHSAADLGLPDSLVGTNEKNQTIEIAGVTWECAAFNADTLGTYTFQLALPAGYTAAGETTTITVVLYNEFAAGGLQYWILTEAPEGAVALAGWAGAPQVSLKVPAAVSNGGSSYRVTEVVPNAFENDGAIKNLDLSGADNLTEIGAYAFADCRATNPLTIPANVVRIGNCAFAGGYFFALNLQGAARLTTIGIFAFSNLRIKGTVTIPGGVTSIGSLAFENCESLEVLDLSAFRGTLGESVFSDCRRLSTVIFGQAEAPKLPDDTFEDAGLSGGYIHCPKGATGYEKVLGLFSGGWSLDYLDIHTVTVNGAVGGTGWVASGSTGGAGGIVSLGAQPQSGYAFVRWDTEPAVTWLDGTNQYDAGAFFSMPDRDVVVTPVFSLMYGLSGTVSANGRPTPGGLQVTLYNAAGKRVGSAATNADGKYTFSGLTAGTYQVTVMGATISDIQYYQTTREFELTDRDRTDADVALETGVTQVGFVSAKANGTQNLDTSTQIDLRFDVPVPLTKNCVALKFNDGGAADVIRLVDEGQLKTDWVLEIGNVVTPANKGYVGGQRDRRSAAGLSIHRRRVGQPETVHCEPPAGASLHHRRKL
>NZ_CP036524.1|WP_040434923.1|3052805_3053495_-|response-regulator-transcription-factor
MDDKGTVLLVEDDKAIMRTNRRILERDGFRVLCAQTLAQARTQLKSQPDVLVLDIMLPDGSGLDFCGEIRRHTAAPVLFLTALDEQHEVIKGLKSGGNDYITKPYSVDEFAARVSAQYDLARRVRQSAGREHLLTCGALELDVIAQRAYMSSQDMLLTQKEFALLMYLMQNRSKDTSPQLLYETVWRQPMADDDSAVKNTVYRLRKKLEGSGYTITTRRGEGYRFEEVL
>NZ_CP036524.1|WP_006442827.1|3053805_3054069_+|hypothetical-protein
MFRLWGKEFKDNKMLRDTVICDDSDDTRTHKIFSALDAICYEFDLSKPIWFDATVEEFRRHDKARFYQDNFVDSIDFDYLEIHVIEE
>NZ_CP036524.1|WP_040434926.1|3054135_3055554_-|ABC-transporter-permease
MNWMDLLRMSGSNLKRRKLRTFLTVLGVVIGTASIVVMISLGLGMQQSLYKEVEQSGGLTTITVTGKDAGQSMMAYSGQENSDESTQYVTDRTIKQLSELGHVTTAAPVYEMSVIMLKGKYEAYIQLVGMTPEGLKAKNIELGEGSLPKQGGSQLDILYGNTVITNFSERNSQSSYWDTGELPEIDLMKDSVFLILDQDGYFRSQEQSFGNSDSGGNESGGPGESQPSQPVKKHAVTASGIVAGGPDDYNANAYSAFCDLETLKKVLKKDFSGRTVPGQPTTKSGKPYKEFCYTSAQVKVDDIDKVEEVSSIIREMGYNTQTNAEYLDSMKSQFAIVQAVLGGIGAVSLLVAAIGIANTMMMSIYERTKEIGVIKVLGCSLKNIKQMFLLEAAFIGLIGGLVGNILSFIMSGIINFLTGNGSAMGIDGNISYIPWWLVLLSMGFAVFVGVAAGYFPSLRAMRLSPLAAIRSE
>NZ_CP036524.1|WP_006442829.1|3055516_3057028_-|hypothetical-protein
MKTIKKLLAALIVSAVTASTFLPFPAKAAGDQITLETSGVLTYQYQKPQKFVVNVKNNTDSEIKNIVVSPDMKDDVSQWPFKTEAQKYTAKIDALAAKETKPVEFNFTERDDVPSTRYTLLFNFTADGGISGSQSFYVLTTAKPEDKKNNSGQDEQRRPAQVQTSSGSGEGVPASADAGGFSNGGASYSGGGEEGSGSTGSVPRVIVTGFDTDPAEVRAGSNFKLTVHLKNTSKATRVSNMLFDLKAPTEGADEQTTSPAFLPSSGSSSIYLDGIKAGGAADITIQLNAKADLLQKPYSIDLSMKYEDGNAAQIEGASSISIPVKQDARFEFSEFEISPETITVGEEANVMCSLYNLGRIKLYNVKASFEGKCVKKAETFIGNVESGATASIDATLEGTKESAGSEKVTMTLSYEDEAGKVSTMTKDLQIEVGPEGMNDMPAAEMEETEQGGLPVIPIAIAVIIVAAAAAAVIIIKKKKKKQMADKEEELLNELDGPSEDERE
>NZ_CP036524.1|WP_006442830.1|3057024_3057747_-|ABC-transporter-ATP-binding-protein
MAKVIEVRDLYKLYRVGDEIVRALDGLDFSIYEGEFCAIVGTSGSGKSTLLNMLAGLEKPTKGSVVIGGQHIETLNEEQLVKFRRENVGFIFQSFHLLGTLNALENVALPLSFRGMSKEKRLKKADEMLDLVKLKKHKNHRPNQMSGGQQQRVGVARALVVDPKIIFADEPTGNLDSHTSEEVMSLMQQVVREQKKTLVMVTHDSHLATYADRIFHIRDGNIINIEENRRKETVEGGLSL
>NZ_CP036524.1|WP_006442831.1|3057925_3058246_+|PadR-family-transcriptional-regulator
MIFPMNTPMFDLLVLAVVEKEDSYGYQISQVIKQVSNTKDSTLYPVLRRLQEQRYLTAYDQPYQGRNRKYYRITDEGRQTFEMLSEEWSLYKNAVDDIVKGGMNIE
>NZ_CP036524.1|WP_040434928.1|3058238_3058829_+|DUF1700-domain-containing-protein
MNRADYMKSLEHGLKRLPKEDYDRAISYFEEYFEEAGPDNEKQAIEDLGSPAMAADQIIRDFAVENAEKPTKNVKRSFSAVWVGILAVFAAPVGLPLAFAAAALGLAFILVIVSLIFAVFCTALAFAASSVPAVMAGIWFLFTSPASGIATIGAGLIGAGIGIWVIIGCITLCRWFLNTMTKLFGRIAKGGNRHEK

Crispr_ID: NZ_CP036524_5

• CRISPR_ID: NZ_CP036524_5
• CRISPR_location: 3089319-3089393
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP036524_5

Consensus_repeat	Method
CTTCTGCCTTAACGCTCCTTCTGCC	CRISPRCasFinder

spacers of NZ_CP036524_5

>5.1|3089344|25|NZ_CP036524|CRISPRCasFinder
TTAACGTCCTTCTGCCTTAGCGTCT

CRISPR arrays and Neighbor proteins around NZ_CP036524_5

CRISPR arrays

The CRISPR arrays of NZ_CP036524_5

>merge|NZ_CP036524|5|3089319-3089393|CRISPRCasFinder
CTTCTGCCTTAACGCTCCTTCTGCCTTAACGTCCTTCTGCCTTAGCGTCTCTTCTGCCCTAACGCTCCTTCTGCC

>NZ_CP036524|5|4|3089319-3089393|CRISPRCasFinder
CTTCTGCCTTAACGCTCCTTCTGCC	TTAACGTCCTTCTGCCTTAGCGTCT
CTTCTGCCCTAACGCTCCTTCTGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_149301937.1|3102939_3103536_-|EpsG-family-protein	unknown	unknown	gnl|CDD|379716
NZ_CP036524.1|WP_006442836.1|3062025_3063030_-|stage-V-sporulation-protein-AD	unknown	unknown	gnl|CDD|377836
NZ_CP036524.1|WP_040434948.1|3098898_3099123_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|179197
NZ_CP036524.1|WP_170254072.1|3110133_3110451_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_149301938.1|3103627_3103885_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442835.1|3061544_3061901_-|stage-V-sporulation-protein-AE	unknown	unknown	gnl|CDD|377146
NZ_CP036524.1|WP_149301934.1|3100872_3101157_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_149301939.1|3104517_3104817_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP036524.1|WP_170254070.1|3072819_3073494_-|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl|CDD|293739
NZ_CP036524.1|WP_149301935.1|3102061_3102247_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_149301931.1|3073523_3074405_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_149301929.1|3072184_3072829_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_149301928.1|3068492_3068909_-|anti-sigma-F-factor	unknown	unknown	gnl|CDD|179626
NZ_CP036524.1|WP_149301936.1|3102459_3102876_-|hypothetical-protein	unknown	unknown	gnl|CDD|215555
NZ_CP036524.1|WP_006442840.1|3066867_3067542_-|stage-V-sporulation-protein-AA	unknown	unknown	gnl|CDD|378824
NZ_CP036524.1|WP_170254057.1|3086264_3086495_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_149301933.1|3089430_3089904_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP036524.1|WP_149301932.1|3086793_3087477_-|recombinase-family-protein	unknown	unknown	gnl|CDD|239737
NZ_CP036524.1|WP_050765500.1|3063085_3065809_-|cation-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319781
NZ_CP036524.1|WP_170254071.1|3104937_3105246_-|hypothetical-protein	unknown	unknown	gnl|CDD|340850

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_149301937.1|3102939_3103536_-|EpsG-family-protein	gnl|CDD|379716	pfam14897, EpsG, EpsG family. This family of proteins are related to the EpsG protein from B. subtilis. These proteins are likely glycosyl transferases belonging to the membrane protein GT-C clan.	0.000147581
NZ_CP036524.1|WP_006442836.1|3062025_3063030_-|stage-V-sporulation-protein-AD	gnl|CDD|377836	pfam07451, SpoVAD, Stage V sporulation protein AD (SpoVAD). This family contains the bacterial stage V sporulation protein AD (SpoVAD), which is approximately 340 residues long. This is one of six proteins encoded by the spoVA operon, which is transcribed exclusively in the forespore at about the time of dipicolinic acid (DPA) synthesis in the mother cell. The functions of the proteins encoded by the spoVA operon are unknown, but it has been suggested they are involved in DPA transport during sporulation.	0
NZ_CP036524.1|WP_170254070.1|3072819_3073494_-|sulfatase-like-hydrolase/transferase	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	1.10812e-34
NZ_CP036524.1|WP_006442835.1|3061544_3061901_-|stage-V-sporulation-protein-AE	gnl|CDD|377146	pfam03862, SpoVAC_SpoVAEB, SpoVAC/SpoVAEB sporulation membrane protein. Members of this family are all transcribed from the spoVA operon. Bacillus and Clostridium are two well studied endospore forming bacteria. Spore formation provides a resistance mechanism in response to extreme or unfavourable environmental conditions such as heat, radiation, and chemical agents or nutrient deprivation. The reverse process termed germination takes place where spores develop into growing cells in response to nutrient availability or stress reduction. Nutrient germinant receptors (GRs) and the SpoVA proteins are important players in the germination process. In B.subtilis the SpoVAC and SpoVAEB, belonging to this domain family, are predicted to be membrane proteins, with two to five membrane spanning. Biophysical and biochemical studies suggest that SpoVAC acts as a mechano-sensitive channel with properties that would allow the release of Ca-DPA (dipicolinic acid) and amino acids during germination of the spore. The release of Ca-DPA is a crucial event during spore germination. When expressed in E.coli SpoVAC provides protection against osmotic downshift. Furthermore, SpoVAC acts as channel that facilitates the efflux down the concentration gradient of osmolytes up to a mass of at least 600 Da. Another conserved SpoVA protein in all spore-forming bacteria is SpoVAEb, which appears to be an integral membrane protein with no known function.	3.89886e-44
NZ_CP036524.1|WP_149301939.1|3104517_3104817_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	9.3725e-09
NZ_CP036524.1|WP_149301936.1|3102459_3102876_-|hypothetical-protein	gnl|CDD|215555	PLN03063, PLN03063, alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional.	0.00236966
NZ_CP036524.1|WP_149301928.1|3068492_3068909_-|anti-sigma-F-factor	gnl|CDD|179626	PRK03660, PRK03660, anti-sigma F factor; Provisional.	8.86034e-60
NZ_CP036524.1|WP_040434948.1|3098898_3099123_-|acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	1.01844e-28
NZ_CP036524.1|WP_006442840.1|3066867_3067542_-|stage-V-sporulation-protein-AA	gnl|CDD|378824	pfam12164, SporV_AA, Stage V sporulation protein AA. This domain family is found in bacteria - primarily Firmicutes, and is approximately 90 amino acids in length. There is a single completely conserved residue G that may be functionally important. Most annotation associated with this domain suggests that it is involved in the fifth stage of sporulation, however there is little publication to back this up.	6.51204e-38
NZ_CP036524.1|WP_149301933.1|3089430_3089904_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.97776e-17
NZ_CP036524.1|WP_149301932.1|3086793_3087477_-|recombinase-family-protein	gnl|CDD|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	4.06597e-40
NZ_CP036524.1|WP_050765500.1|3063085_3065809_-|cation-translocating-P-type-ATPase	gnl|CDD|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP036524.1|WP_170254071.1|3104937_3105246_-|hypothetical-protein	gnl|CDD|340850	cd03823, GT4_ExpE7-like, glycosyltransferase ExpE7 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).	0.00842201

Protein sequences

>NZ_CP036524.1|WP_149301932.1|3086793_3087477_-|recombinase-family-protein
MNKKCYGYVRVSSKEQNIGRQIAALEKIPVPPENIFIDKQSGKDFDRPNYQKMIDKLCAGDVVFVKSIDRLGRNYDEIIEQWRVLTKAKDVDIVVIDFPLLDTRNQVNGLTGKFIADIVLQILSYVAQIERENIRQRQAEGMRGKVKGVSFGRPAKEIPEEFPHVFELWRQGKISMRRAAKIMGTNHTTVSKWIKLYMKENDIFLGTKRYKIGWKCRLFYPSMILLF
>NZ_CP036524.1|WP_170254057.1|3086264_3086495_-|hypothetical-protein
MGYIIGNNTIQINDCKDAKEYLIHKLWKGVIEWVGDGGFKNLRPQPAFTLSLLRSYSEAHVRSNKHVYKISEKYSK
>NZ_CP036524.1|WP_149301931.1|3073523_3074405_-|hypothetical-protein
MKIQIKRPDIKGTFHKLKNMNKEDVKAYWKARKERRAMIIEQRRNSAFARKMKPVYKFMNRFSLLFHALLACVLNIVIEAISRHSLFEALDYMTGTPMVFLYNAFMIFITFSIVYLFRRRVFVRILISVFWLILGVANGYMLLKRVTPFNAQDLKVAKDGLSLINNYFNGFELIVLAIGIVSVVIWVVSMWKRGGQFEGKVHHVWALLGIIVCFAAYGLFSNLAVEKRVVSTYFGNIAFAYEDYGLPYCFMASVFNTGITEPNDYNKKTIEKISNNGEITKMRPGVPRMNFRT
>NZ_CP036524.1|WP_170254070.1|3072819_3073494_-|sulfatase-like-hydrolase/transferase
MAEAEFFTTSEDASPNLHEMYKKYSSGYFKVPSVGAGTANTEFEVLTGMNLRYFGPGEYPYKTVLKNQTAESRHSSGRPRLWGACPAQQRGNFYSRANVFNNIGFDSFTSKEFMNILQTTENGWAKDDILIQHIIDAMNTTEQRDFVFGVSVQGHGDYPEEQIIENPKIKVEGIEDEGLKNKWEYYVNQVYEMDKFAGDLVKTLEERGEPTVVVFTATTCRLWG
>NZ_CP036524.1|WP_149301929.1|3072184_3072829_-|hypothetical-protein
MGLKAEDLKSRYLYNTNYVIWDNIGLQKEDRNIPSYQIMADVFDRLDIHSGTVFNYHQERRKTKNYLSDLELLQYDILYGKQYVYNGKEPITEGHMQMGVKDVTLTNVVKHLNEGCSLYGENFTRHSKIFINGEKQKSTFLNNTRIDLPETVPEDGDVITVVQMGSSNTPFRTSNEYVYQDGTLTVRKGLEQTRRNPGQSRQTVQKNKGEHSEL
>NZ_CP036524.1|WP_149301928.1|3068492_3068909_-|anti-sigma-F-factor
MENTNEMQLIFDSRSSNESFARVTVAAFMTSLNPTVEEVSDVKTAVSEAVTNAIIHGYENEVHNIYIRCRTEGKTLYLEIEDKEKDPGCRKGHGTAFTTKPELDRSGMGFSFMEAFMDHLDVVSEPGKGTTVKWKNYW
>NZ_CP036524.1|WP_006442840.1|3066867_3067542_-|stage-V-sporulation-protein-AA
MAANSETVYIKADRNVEVTKPDVTLGDVLTMECSNPSVVPKLNTLKLLKFHHTDKKNQNRVAISILKVIEIIHEQFPNMDIQNLGEQDFIVTYEQQQTAGGLVHLLKAACVIVITFIGAAFSIMAFNNDVDTVKLFSQIYELVTGQKSDGFTVLELTYCIGIIIGILIFFNHFGKKKFTVDPTPMEVEMRLYENDIQTTLIETYSRKGKEQDVGSTNTSGTHRT
>NZ_CP036524.1|WP_050765500.1|3063085_3065809_-|cation-translocating-P-type-ATPase
MFENKTVRETCEELQTDSEYGLSYTEAAQRLQDNGANELKSAKKKTKVESFFEQLNDPLIYVLLAAAAVSILLQEVSDAIIIIVVVLMNAFVGIIQEGKAQKALDSLKKLTSPRAVVIREGKEQEVQASSLVPGDIVCLDAGCQIPADLRLVKANNLKVEESALTGESLPIEKNVDFIAGKGMGRGYKASSVPLGDRKNMAYMSTIVTNGRGLGIVTATGMNTEIGKIAALINDSQEEITPLQKRLGELGKMLSILSLGLCAALFFIAVLQHRNMAEMLITAISLAVAAVPEGLPAVVTICLALSVTRMVKVHTIVRRLPSVETLGAVSVVCSDKTGTLTQNRMTVEGCYIDEKIVDSSELKLREHSELLQGMTLCNDAVQKDGSSIGDPTELALLNLAGQYGIRRETLEREMPRKKELPFDSERKMMSTMHKNGSTNITYTKGAPDVVLKRCSRILIRGKVTAMTDTHRRQIQEAIEKMSSQALRTLAVAMRTGGNAPVERELTFVGMVGMRDPARPEAKGAVARFRQAGVTTVMITGDHVDTAFAIARQLGIVERQEQCMTGEEIQSLPDEKFLRKLDDVRVFARVSPEHKVRIVKGFKTKGNIVAMTGDGVNDAPSLKSADVGIAMGMTGTDVARQASDIILTDDNFATIEKAIEEGRGVYENIRKTVIFLLSSNLGEIMTMFLAVLCDIASPLKSSHILWINLITDSLPALALGVDENDGDSLMEEPPRKPKESLFARGGLACTCFYGLLIAGISLTAFFTVPYELIMSKGASFSISNIALALQNSDILMRAQTYAFTVLGMSQLFHAVGMRDIHKSVFRMNHFENKWMIAAFVLGFVLQISVTEVPVLIKAFGTVHLEFHEWLRLTILAAFPILAHEFMVFLQKPEKDVCNQVKMESIRIDR
>NZ_CP036524.1|WP_006442836.1|3062025_3063030_-|stage-V-sporulation-protein-AD
MIQGLQSIAFENSPYIVESASVVGKKEGEGPLGSMFDMVEENDLFGEDTWEAAESTMQKQACVLALGKAHMEAGEIRYLFGGDLLRQGVATSMGVEELNIPMFGLYGACSTSGEAIALASMSVAAGYGDNMLAVTSSHFGSAEKEFRFPLGYANQRPLSAHWTVTGSGAFVVGTKRSHVRVTGITVGKIVDYGLKDSQNMGACMAPAACDTILRNLEDFGRTPDDYNRIVTGDLGYVGQSILFDLMRGKNVDIKKNHMDCGMTIYDQKTQDTHAGGSGCGCAAVTLSSYILPKLARGEWKRILFVPTGALMSTVSFNEGESVPGIAHGIVLEHC
>NZ_CP036524.1|WP_006442835.1|3061544_3061901_-|stage-V-sporulation-protein-AE
MDYVNAFWIGGLICALVQILLDRTKLMPGRIMVLLVCSGAVLGALQIYEPFLKFAGAGASVPLLGFGNVLWKGVKEAVDSHGFIGIFMGGFKASAVGISAALIFGYLASLIFEPKMKK
>NZ_CP036524.1|WP_149301933.1|3089430_3089904_-|MarR-family-transcriptional-regulator
MENAYKTINHILVNLINEIWELEEKAIITEEFKDLTNNDMHVIEAVGLGEGNNMSAIARKLGITVGSLTTAMNSLVNKKYVERRRSEEDRRVVYVKLTNKGVGAYRHHEDYHRQMTQAILDKLGEDEIPVLVKTLDALDEFSVVTASRDSQAEGREG
>NZ_CP036524.1|WP_040434948.1|3098898_3099123_-|acyl-carrier-protein
MLEKIKSMVADNLGVEESTITEASSFKDDLGADSLDLFELMMALEEEFGVEIPTEDLEQIVTVGDVIKYVEAHK
>NZ_CP036524.1|WP_149301934.1|3100872_3101157_-|hypothetical-protein
MVYVMFCCKDIMFLKETSIGSYRREKAIQSGYKLLFATLAGTVIIGITRWCIENHWNITTFAEVTLTISIANVFLQCINAVAVTLFLLYEGQIK
>NZ_CP036524.1|WP_149301935.1|3102061_3102247_-|hypothetical-protein
MEKIGNALSIQRGKYAFVYLVGVDKVHRRVIREYCDREQIKLISIPHAQGHYKRKMKNLHI
>NZ_CP036524.1|WP_149301936.1|3102459_3102876_-|hypothetical-protein
MEKCGIITLYHKNYNYGGILQAYAMVKIMGELGYDAEIIDYCQSYKALVIHKITKLRISEMLSIFKRKLGLKVLNILFPEIKKGIKGRYVNFEKFMEKIPHSVTYSEKILGSVKIDTRLLLQEVIRFGIQVHGMISIF
>NZ_CP036524.1|WP_149301937.1|3102939_3103536_-|EpsG-family-protein
MIPSNIASLIVIGGFCFILERKLWKFLLIIVLAMQMHQSVFIFIALYILHSIKLTRFRAVLLFGAGGIVLMLYDRLLPVISLFVPDVYQRYLMTSQITNGVVFGFHILIFIFILVVTDFRKAGSSFNLYLWAFIMELEFYWLSFRLEIFPGYLFVQSCSHFTCAICDRQYEICKKQKTYQRDILYAYRCAVRIEIKYK
>NZ_CP036524.1|WP_149301938.1|3103627_3103885_-|hypothetical-protein
MDVAFWGAVIFPAAIAVLRGITVGADTKNYYAYYEDIVQLHTWKDLSYYADKYLIETGYMIYNKILGFSLNQDRRSQFVIVFCYS
>NZ_CP036524.1|WP_149301939.1|3104517_3104817_-|glycosyltransferase-family-4-protein
MIILPYRTATQSGVVIDAYKASRYVVAFDVGAIGEQIKNHISGELIESGNIKKFSQALNDFFELTFEERKKRSLAAWDYRMNKFSIQNNVQEWIKLINE
>NZ_CP036524.1|WP_170254071.1|3104937_3105246_-|hypothetical-protein
MIHDIIPHEGDRQEKVLKVFNRLIGIFSNYVVVHNRKYIDYLSKEYKVKFSNIKFIDIYKDFGKYTPLQQTKRVLFLGRINLYKGVEYLEEIIKECPDFHLI
>NZ_CP036524.1|WP_170254072.1|3110133_3110451_-|hypothetical-protein
MRYMLPIQTTIIYGKNDYERLVKKIEALKKIHIVAGCFAEKEIKSELEQYLNKCQKVYLYEVSNSCKKYFINYCENKNVELYITRDIEEILTSEYEISHSLDIPL

Crispr_ID: NZ_CP036524_6

• CRISPR_ID: NZ_CP036524_6
• CRISPR_location: 3169620-3169885
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP036524_6

Consensus_repeat	Method
GGCCCCTGCGGGCCCGCTGCTCC	CRISPRCasFinder

spacers of NZ_CP036524_6

>6.1|3169643|22|NZ_CP036524|CRISPRCasFinder
GGCATCTCCTTTGTCGCCTTTC
>6.2|3169688|31|NZ_CP036524|CRISPRCasFinder
CGGATCTCCCTTTGGACCCGTGGCTCCGGTT
>6.3|3169742|22|NZ_CP036524|CRISPRCasFinder
TGTGTCTCCTTTGGGTCCTGTG
>6.4|3169787|22|NZ_CP036524|CRISPRCasFinder
CGTCGGCCCCTGGGGGCCGGTC
>6.5|3169832|31|NZ_CP036524|CRISPRCasFinder
CTGAGGACCTGTGACTCCGGTCAGTCCCTGA

CRISPR arrays and Neighbor proteins around NZ_CP036524_6

CRISPR arrays

The CRISPR arrays of NZ_CP036524_6

>merge|NZ_CP036524|6|3169620-3169885|CRISPRCasFinder
GGCCCCTGCTCTCCTGCAGTACCGGCATCTCCTTTGTCGCCTTTCGGCCCCTGCGGGCCCGCTGCTCCCGGATCTCCCTTTGGACCCGTGGCTCCGGTTGGCCCCTGCGGGCCTGCTGCTCCTGTGTCTCCTTTGGGTCCTGTGGCTCCCTGCGGACCGGTAGCTCCCGTCGGCCCCTGGGGGCCGGTCAGTCCCTGTGGCCCCGTAGCTCCCTGAGGACCTGTGACTCCGGTCAGTCCCTGAGGCCCCATCGGGCCCGCCTCACC

>NZ_CP036524|6|5|3169620-3169885|CRISPRCasFinder
GGCCCCTGCTCTCCTGCAGTACC	GGCATCTCCTTTGTCGCCTTTC
GGCCCCTGCGGGCCCGCTGCTCC	CGGATCTCCCTTTGGACCCGTGGCTCCGGTT
GGCCCCTGCGGGCCTGCTGCTCC	TGTGTCTCCTTTGGGTCCTGTG
GCTCCCTGCGGACCGGTAGCTCC	CGTCGGCCCCTGGGGGCCGGTC
AGTCCCTGTGGCCCCGTAGCTCC	CTGAGGACCTGTGACTCCGGTCAGTCCCTGA
GGCCCCATCGGGCCCGCCTCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006442965.1|3171915_3172905_-|YegS/Rv2252/BmrU-family-lipid-kinase	unknown	unknown	gnl|CDD|183982
NZ_CP036524.1|WP_040434972.1|3173267_3174149_-|DNA-binding-protein-WhiA	unknown	unknown	gnl|CDD|224398
NZ_CP036524.1|WP_170254092.1|3164282_3164648_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223673
NZ_CP036524.1|WP_006442961.1|3167640_3168708_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP036524.1|WP_006442973.1|3177465_3178176_-|hypothetical-protein	unknown	unknown	gnl|CDD|223642
NZ_CP036524.1|WP_006442975.1|3180444_3180687_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_040434977.1|3178358_3180362_+|DUF5107-domain-containing-protein	unknown	unknown	gnl|CDD|375006
NZ_CP036524.1|WP_006442960.1|3166723_3167647_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|225070
NZ_CP036524.1|WP_149301977.1|3162756_3162954_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_040434969.1|3165876_3166752_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|225070
NZ_CP036524.1|WP_006442964.1|3170526_3171900_-|sodium-dependent-transporter	unknown	unknown	gnl|CDD|271367
NZ_CP036524.1|WP_149301979.1|3163520_3164084_-|hypothetical-protein	unknown	unknown	gnl|CDD|270279
NZ_CP036524.1|WP_040435512.1|3165070_3165874_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224041
NZ_CP036524.1|WP_006442972.1|3176136_3177414_+|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP036524.1|WP_040434974.1|3175067_3175979_-|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl|CDD|237553
NZ_CP036524.1|WP_149301982.1|3164864_3165071_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006442966.1|3172998_3173256_-|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|376329
NZ_CP036524.1|WP_149301978.1|3163060_3163501_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_170254093.1|3164706_3164868_-|hypothetical-protein	unknown	unknown	gnl|CDD|223673
NZ_CP036524.1|WP_006442970.1|3174184_3175066_-|RNase-adapter-RapZ	unknown	unknown	gnl|CDD|235450

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006442965.1|3171915_3172905_-|YegS/Rv2252/BmrU-family-lipid-kinase	gnl|CDD|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	3.98832e-64
NZ_CP036524.1|WP_040434972.1|3173267_3174149_-|DNA-binding-protein-WhiA	gnl|CDD|224398	COG1481, COG1481, Uncharacterized protein conserved in bacteria [Function unknown].	1.00852e-93
NZ_CP036524.1|WP_170254092.1|3164282_3164648_-|ABC-transporter-permease-subunit	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.96833e-21
NZ_CP036524.1|WP_006442961.1|3167640_3168708_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.54338e-114
NZ_CP036524.1|WP_006442973.1|3177465_3178176_-|hypothetical-protein	gnl|CDD|223642	COG0568, RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription].	1.36374e-07
NZ_CP036524.1|WP_006442960.1|3166723_3167647_-|amidohydrolase-family-protein	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	1.58967e-13
NZ_CP036524.1|WP_040434977.1|3178358_3180362_+|DUF5107-domain-containing-protein	gnl|CDD|375006	pfam17128, DUF5107, Domain of unknown function (DUF5107). This family is found in range of different bacterial species. In many proteins it lies N-terminal to a TPR-repeat region at the C-terminus.	9.79484e-31
NZ_CP036524.1|WP_040434969.1|3165876_3166752_-|amidohydrolase-family-protein	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	4.33879e-22
NZ_CP036524.1|WP_006442964.1|3170526_3171900_-|sodium-dependent-transporter	gnl|CDD|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	5.31033e-173
NZ_CP036524.1|WP_149301979.1|3163520_3164084_-|hypothetical-protein	gnl|CDD|270279	cd13561, PBP2_SsuA_like_4, Putative substrate binding domain of sulfonate binding protein-like, the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0.00204221
NZ_CP036524.1|WP_040435512.1|3165070_3165874_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.04833e-102
NZ_CP036524.1|WP_006442972.1|3176136_3177414_+|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	4.42307e-123
NZ_CP036524.1|WP_040434974.1|3175067_3175979_-|UDP-N-acetylmuramate-dehydrogenase	gnl|CDD|237553	PRK13905, murB, UDP-N-acetylmuramate dehydrogenase.	5.36632e-164
NZ_CP036524.1|WP_006442966.1|3172998_3173256_-|HPr-family-phosphocarrier-protein	gnl|CDD|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	3.04355e-24
NZ_CP036524.1|WP_170254093.1|3164706_3164868_-|hypothetical-protein	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	7.03651e-06
NZ_CP036524.1|WP_006442970.1|3174184_3175066_-|RNase-adapter-RapZ	gnl|CDD|235450	PRK05416, PRK05416, RNase adapter RapZ.	4.91892e-153

Protein sequences

>NZ_CP036524.1|WP_006442961.1|3167640_3168708_-|LacI-family-DNA-binding-transcriptional-regulator
MSKKESKITISQIAKMANVSTSTVSHVINGTKNVSDRTRLKVAGIINETGYTPNYVAKALKKSETKTIGLIVSDITNQFFVDVIQAVNEEALRNGYMVILGDSDDNPKQELELVKSFQERCIDGLIFSPTIHSGNYAAPYLNSVNLPAVCIDRTLDDKWDWVGTENRNAAKILTRHLIGLGHRRIAFVSGLRGINTTEERIEGYESALKEAGLPFDKTLLIVGESRIVPAKVRSKERFKAILNTENFPTAIIASNNLMVIGIMRTLQELNVKVPEDMALAAFDDFEWADLFQPRITTIVQPCRDIGTKAVQLLIERIKNPTAALQKVEYYPRLEIRESCGILLKDKLKKEGVKKW
>NZ_CP036524.1|WP_006442960.1|3166723_3167647_-|amidohydrolase-family-protein
MVKERWPVIDTHYHTGVCLINTFDAEKELIPWMDKNGVDIQVIFQVNEGFVHKTPDWNPYIGNDYISRIQHKFPDRVIGLCTINPWLQAPKTYNWPKSKYGKEMDLPIRDEALEELERSILELGLWGIKLHPLEHDFEINNKSIIYPIMEKLTRLQEKCGRKLFVVVHCAGDSVNNTPTQLAQVAADFPDILFLMAHAGYMRAFGTAGDVAEGIDNLKLDLTLNVTPTTLKPTYEKEGAGKFVIGTDGPFDLATTKRLIVRDLTGEDDEEAVELVMGGNMAEYLGIPKIKYEEQEDENRGKISLAGN
>NZ_CP036524.1|WP_040434969.1|3165876_3166752_-|amidohydrolase-family-protein
MGKYRWPVIDTNFKIGVNMKSTCVAEEDLIPWMDENGIDIQIVFQADEGFAHQTPKWNPYIGNDYVAKIQDMFPERVIGLATVNPWNDAPKTWNYPPDETGRPFTLPVADESSRELERCIVDLGLKGLRMNPAAHNYEINNKTVVYPMLNKLRELQERTGRVLPVVVHGAGDSGNTTALQVAEVAKDFPKLVFLMIHSGFIWCYGTTGEIAPSYDNLLLDLTGNLGPYSVSEAYRQCGAGKFTIGTDGPLGIPGIKDKILDVFVDNEEDRELILGGNIAKLLGIEKIEVAR
>NZ_CP036524.1|WP_040435512.1|3165070_3165874_-|ATP-binding-cassette-domain-containing-protein
MGEVEKKTQSGELNIEHVSIEFNTVSGDKMKALDDISLDVAHGELVAVVGRSGCGKTTLLNIVAGLLEPTGGTCRLNGKEITGPGRERGVVFQADAVFGWKRVGDNVDFALKLGGVPKEERGQLITKYLKMVNLEKFTKFYPKELSGGMRKRLQIAMVLANQPKLLLMDEPFGPLDYATKVELQVEVEKIRLKNPLTTFFVTHDVEEATFVADRIIMIEKGKIVEELKVDIPRPRPVEIRNTAEFHAISDYLLGKLLELSDVKSEVR
>NZ_CP036524.1|WP_149301982.1|3164864_3165071_-|hypothetical-protein
MGTKHIKKILAAAGLIVFWQIAALIARSGGEYSAVLVPTWGKVLTESLPGFAAFRERAAELCGCAVRP
>NZ_CP036524.1|WP_170254093.1|3164706_3164868_-|hypothetical-protein
MSNSLITVKRVVTGLFIGGAAGVVTGIIIGLQPVLRGMFYPVVKILRNIRFWR
>NZ_CP036524.1|WP_170254092.1|3164282_3164648_-|ABC-transporter-permease-subunit
MDSGSYTTNIIEAIDNTDRIRINFARTLGAKNMDVYTNVIIPMIVPNIINATKVALGVAWAIALGGEFLAAQDGLGRLLIVSQQYMETGRMLIILIVFIVLTAIFGWIVKVTGNRITRWMP
>NZ_CP036524.1|WP_149301979.1|3163520_3164084_-|hypothetical-protein
MWALKKVFEDVGITLEKVDAIDADKVPSVLIAGNYDFASGAPSLFIPSMGQGDFTTFAFSNLFLGYSVMAPEGTKTYSDFVKEGMSGEEAIKAALGQMKGKVFTYPSESAIKPFIDLCFQKAGMTLDDVENEVIDDSNGVALMLAGRADFKVGGVRQPQLCLPRDLYRSFLPRISWRLQSLQRTQRK
>NZ_CP036524.1|WP_149301978.1|3163060_3163501_-|hypothetical-protein
MDNDRKWAEENHDTVLRLASVCFRINQYVNDDPKEAAKIHVNYVNQLAGTEFTEEEVQALYKTSIPLYTWDMQKPWFEDKEDALYWEYEIGSTIKMYEDEGMFKSGEYGPSDIVSADKIYAELKELKAEADSNFENWKMQTARRWS
>NZ_CP036524.1|WP_149301977.1|3162756_3162954_-|hypothetical-protein
MTKKKNIFLAARHYDIVCRMDLGKFSLGETRVPSPWKIVSRFAGTITESPEIQFQEPGAVAFLHM
>NZ_CP036524.1|WP_006442964.1|3170526_3171900_-|sodium-dependent-transporter
MEKREKFSSRLGFILISAGCAIGLGNVWRFPYITGKYGGGAFVLMYLFFLVILGLPIVVMELSVGRGSQKSSAMSFNALEPAGSKWHVFRYFSMAGNYLLMMFYTTIGGWMLAYFVKMLKGDFEGADTAQVEGVFTALTSDRNGMLFWMVLISVAALLICSMGLQKGVELITKVMMSSLLVIMIVLVIRAVTLPNAADGLKFYLLPDFGKMEEAGIKEAVFAAMGQAFFTLSVGVGSLAIFGSYIGKERSLAGEAVSITALDTFVAVVAGLVIFPACFAFDLNPGEGPGLVFVTLPNVFREMPGGRVWGSLFFLFMTFAALSTIVAVFQNIIQFARDLWDWPLRRSVIVNGVLLILLSIPCVLGMTDWSSFTIGGKNIMDIEDFIVSNNLLPLGSMVYLLFCVTRYGWGWDNFLKEANAGAGMKFPSGRGVRFYLTFILPLIVFVIFIQGYISMIMK
>NZ_CP036524.1|WP_006442965.1|3171915_3172905_-|YegS/Rv2252/BmrU-family-lipid-kinase
MRRLLFIYNPHAGKGLLKPKLSDVIDIFVKAGYEVVAYPTQAYRDAYKKVVQYEFGSYDLVVCSGGDGTIDEVVTGMMQRGDRTPIGYIPTGTTNDFANSLHIPKGLLSAADNAVNGAVFPCDVGRFNDDVFVYIAAFGLFTDVSYQTKQEVKNVLGHLAYVLEGTKRLFNVPSYRIKVTHDGETIEDEFIFGMVTNSRSVGGFRNMIGKQVVFDDGVFEVTLIKMPKNPLELQEIVAALLIEQVDTKHMYSFKTGNIVFESLEEIPWTLDGEFGGIHDRVEVQNLNRQLEIMVPEEHIRELMQNPEEYLLEEKQLEKKQLEDKQLEEK
>NZ_CP036524.1|WP_006442966.1|3172998_3173256_-|HPr-family-phosphocarrier-protein
MIKKPVTIQTDMSTEDRSVALLVQEASQYQSQVFFEVEEKKINAKSIMGMMTLRLCQGEELTVVAEGKDEEEAAKGLELFLSDKK
>NZ_CP036524.1|WP_040434972.1|3173267_3174149_-|DNA-binding-protein-WhiA
MSFSGNIKEELSRHYAKARHCSLAELSAIVHMCGGFQEDAGGTCSLGVHTENIAVARKCFTLIEKTFNIRTDIAVRRNTGRDSSSYFIHARGKELLAVKNASAQAVCCKRSYIRGAFLAAGSMSDPSKSYHFEIVCGDEAKAVHLRDIINSFGMDAKIVPRKKTFVVYLKEGSQIVDILNVMEAHIALMELENVRILKEMRNSVNRKVNCETANINKTVSAAVRQMEDISYIKETVGFDKLPEGLRDVALTRLEYPEATLKELGNLLREPLGKSGVNHRLRKLSEIADKLREQ
>NZ_CP036524.1|WP_006442970.1|3174184_3175066_-|RNase-adapter-RapZ
MRFVIVTGMSGAGKSTALKMLEDVGYFCVDNLPVPLIPKMADLLRVPGTEINKAALGVDIRSGQSFRELEKVLDELDMTGLKYEILFLESSDNVLVKRYKETRRFHPLSGNDSRVDQGIQREREQLKFLKKRADYLVDTSHMLTRELKAELNKIFVQNKEYKNLYISVLSFGFKYGIPNDADLVFDVRFLPNPYYIEELRSESGNDREVRDYVMNNDKAKKFLEKLLDLVEFLIPNYIVEGKTQLVIGIGCTGGKHRSVTLANELFEQLKDTEVYGIRIEHRDIGKDAVTKAR
>NZ_CP036524.1|WP_040434974.1|3175067_3175979_-|UDP-N-acetylmuramate-dehydrogenase
MNQDFYNALKDVLTEDKVLADEPMKNHTTFRVGGAADYYTVPESKEEVRDIIRLCRQWDVPFYIIGNGSNLLVSDKGYRGVMIQIYRDMSEITVEGHTVRAQAGALLSSIAARALSAGLTGFEFAAGIPGTLGGACVMNAGAYGGEMKDVLRYVTVLTEDGAFLTLHRDELELGYRTSVIARKGYIALEAEIELKEGSKDEIKARMDELKEKRVTKQPLEYPSAGSTFKRPEGYFAGKLIEDAGLRGFRVGGAQVSEKHCGFVINRGSATAADIMALITEVADRVERQTGVRMEPEVKRLGEF
>NZ_CP036524.1|WP_006442972.1|3176136_3177414_+|HlyC/CorC-family-transporter
MDSSDVIQLIILVVLLGLSAFFSSAETSLTTANKIRIRSLAEDGSKRAKTLLKITDNSGKMLSAILIGNNIVNLSAASLTTSLAYSFGGSMVAIASGILTVLILLFGEITPKTMATIHAEKMALIYAPIISMFMKIMTPVIFLINGLSMGVLLLLRVDPNAKNDIMTETELRTIVDVSHEDGVIESDEREMIYNVFDLGDAKAKDVMVPRVHVTFADVESTYEELLEIFREDKFTRLPVFEETTDNVIGTINMKDLLLYDNTKEFHIRDILREAYFTYEYKNISELLVEMRQASFNIAIVLDEYGETAGLITLEDILEEIVGEIHDEYDENEEDFIQEIGEREFIVEGSTNLDDLNDRLDLNLESEDYDSVGGFIIERLDRLPEAGDTITTEDGIRMVVETLDKNRIETVHMYLPEREADEDTDD
>NZ_CP036524.1|WP_006442973.1|3177465_3178176_-|hypothetical-protein
MADRLEFRSKLGSIQETAAGQGNRLTVEEIEKFFEEDGLSQEQTELVCDYLLAQKVTVAGYKKQPGKIIESGEESADLSSEEQEYFTEYIQEIENMRGGSVEEARMAYYLPLVADAALQMHRKELFIGDMIQEGNLSLMAALRRFEGAVDSEQEIMEEVRAGLQAFIESQTETRRQDKKMVSQVAELDETIRHMSEDMGRKVSVDEVAQQLSMETEQVEALLKLAGEDVEEEQEEI
>NZ_CP036524.1|WP_040434977.1|3178358_3180362_+|DUF5107-domain-containing-protein
MSITKGILKIEGARPEGANPLPLFRDRQKNKHPKSNGTMRPEELDYFGYESAFRVLPYKMQDRYTRTKTRLTLTSVVLENEHLRAEFLPEFGGRLYSLREKETDRELLYCNPVMQPANLAIRNAWFSGGIEWNIAQLGHTFSTCDDVFFAAVKAGGASGGKEEEFLRMYDYERTRGLVWQIDFHLPEGARSLTAHVRIVNDQPHSVPMYWWTNIAVKEEEGSRVFSGTDEVLYIEPQSQAEGCEHCFGRGQLPDLPVLPGKDASYSLNFDFSSEYFFQNPVSDAAPWEAVSYKDGTVFCERSTQPLRIRKMFCWGSHSGGRSWCDYLSLPGQGDYIEIQAGLAPTQLHGMEMDAQSSIEFTQIFGTAAVQPGEGNLDSYGQAQALIRQAVEQSLPAEEVARADMHCRTLASLPCETILHRGHGWGALENMRRRAENKPLLPASFTFPQDTLGKEQEPWICLLEGRALPELNDTHFPASWMTDANYIPYLERCIKSDPHNTAAQLHLGVNLYENGRYDEAAALWEKALLAKPLPILHRNLACAAHQEGDLKKAIRQMEQITLDTYIAADAAFLQEYLRLLAEDGQWQKLNDIYQKLPARLKEEERIYLLECEAALHLENWSFLEEAFQKEYASIREGETKITDIWFAFAAANQIDPKQLPKNLDLRMF
>NZ_CP036524.1|WP_006442975.1|3180444_3180687_-|hypothetical-protein
MKRLWELTNKTFQNDSATGVFLAANIICWTAAALIAGMLFCVISGVSVLAYATGIMCAAIYVGIIFGLFGGIIFLMRNRV

Crispr_ID: NZ_CP036524_7

• CRISPR_ID: NZ_CP036524_7
• CRISPR_location: 3458775-3458869
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP036524_7

Consensus_repeat	Method
GTAAGGCTGGTGCACCCAGTAAACGC	CRISPRCasFinder

spacers of NZ_CP036524_7

>7.1|3458801|43|NZ_CP036524|CRISPRCasFinder
GCTGCTTTCGATGGTCTGCAGCTTTGATGGGAAGGTCACCTCC

CRISPR arrays and Neighbor proteins around NZ_CP036524_7

CRISPR arrays

The CRISPR arrays of NZ_CP036524_7

>merge|NZ_CP036524|7|3458775-3458869|CRISPRCasFinder
GTAAGGCTGGTGCACCCAGTAAACGCGCTGCTTTCGATGGTCTGCAGCTTTGATGGGAAGGTCACCTCCGTAAGGCTGATGCACCCAGTAAACGC

>NZ_CP036524|7|6|3458775-3458869|CRISPRCasFinder
GTAAGGCTGGTGCACCCAGTAAACGC	GCTGCTTTCGATGGTCTGCAGCTTTGATGGGAAGGTCACCTCC
GTAAGGCTGATGCACCCAGTAAACGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006445105.1|3465158_3466715_-|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NZ_CP036524.1|WP_006445102.1|3462659_3463544_-|ribokinase	unknown	unknown	gnl|CDD|238579
NZ_CP036524.1|WP_040436074.1|3460067_3460790_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225818
NZ_CP036524.1|WP_149301990.1|3468786_3469716_-|transketolase-family-protein	unknown	unknown	gnl|CDD|226467
NZ_CP036524.1|WP_006443233.1|3452363_3455444_-|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|223740
NZ_CP036524.1|WP_040435058.1|3451552_3452245_-|aquaporin	unknown	unknown	gnl|CDD|235453
NZ_CP036524.1|WP_040435057.1|3443649_3445218_-|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173853
NZ_CP036524.1|WP_006443225.1|3448288_3448702_+|DUF3795-domain-containing-protein	unknown	unknown	gnl|CDD|378914
NZ_CP036524.1|WP_040435059.1|3455434_3456232_-|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270409
NZ_CP036524.1|WP_006443222.1|3445662_3447027_-|DUF4368-domain-containing-protein	unknown	unknown	gnl|CDD|239739
NZ_CP036524.1|WP_040436081.1|3469708_3470542_-|transketolase	unknown	unknown	gnl|CDD|238970
NZ_CP036524.1|WP_083790637.1|3447234_3447918_-|cysteine-rich-VLP-protein	unknown	unknown	gnl|CDD|372957
NZ_CP036524.1|WP_040436078.1|3466746_3467400_-|DUF2291-domain-containing-protein	unknown	unknown	gnl|CDD|378370
NZ_CP036524.1|WP_149301989.1|3461164_3462646_-|glycerol-kinase-GlpK	unknown	unknown	gnl|CDD|198378
NZ_CP036524.1|WP_006445107.1|3467588_3468617_-|D-ribose-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380622
NZ_CP036524.1|WP_006443229.1|3450239_3450734_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP036524.1|WP_006445103.1|3463621_3464023_-|D-ribose-pyranase	unknown	unknown	gnl|CDD|183318
NZ_CP036524.1|WP_006445104.1|3464102_3465155_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224093
NZ_CP036524.1|WP_147570498.1|3449631_3450129_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP036524.1|WP_006443223.1|3447051_3447183_-|hypothetical-protein	unknown	unknown	gnl|CDD|372961

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006445105.1|3465158_3466715_-|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP036524.1|WP_006445102.1|3462659_3463544_-|ribokinase	gnl|CDD|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	4.4689e-87
NZ_CP036524.1|WP_040436074.1|3460067_3460790_-|response-regulator-transcription-factor	gnl|CDD|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	5.47032e-23
NZ_CP036524.1|WP_149301990.1|3468786_3469716_-|transketolase-family-protein	gnl|CDD|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	3.88309e-115
NZ_CP036524.1|WP_006443233.1|3452363_3455444_-|mechanosensitive-ion-channel	gnl|CDD|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	3.57164e-39
NZ_CP036524.1|WP_040435058.1|3451552_3452245_-|aquaporin	gnl|CDD|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.42965e-65
NZ_CP036524.1|WP_040435057.1|3443649_3445218_-|peptide-ABC-transporter-substrate-binding-protein	gnl|CDD|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	8.51541e-122
NZ_CP036524.1|WP_006443225.1|3448288_3448702_+|DUF3795-domain-containing-protein	gnl|CDD|378914	pfam12675, DUF3795, Protein of unknown function (DUF3795). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 99 and 171 amino acids in length. This protein is likely to be zinc binding given the conserved cysteines.	7.29274e-10
NZ_CP036524.1|WP_040435059.1|3455434_3456232_-|transporter-substrate-binding-domain-containing-protein	gnl|CDD|270409	cd13691, PBP2_Peb1a_like, Substrate binding domain of an ABC aspartate/glutamate transporter; the type 2 periplasmic-binding protein fold. This group includes periplasmic aspartate/glutamate binding domain Peb1a and its closely related protein. The Peb1a is an important virulence factor in the food-borne human pathogen Campylobacter jejuni, which has a major role in adherence and host colonization. The Peb1a domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.88628e-114
NZ_CP036524.1|WP_006443222.1|3445662_3447027_-|DUF4368-domain-containing-protein	gnl|CDD|239739	cd03770, SR_TndX_transposase, Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. TndX mediates the excision and circularization of the conjugative transposon Tn5397 from Clostridium difficile. TnpX is responsible for the movement of the nonconjugative chloramphenicol resistance elements of the Tn4451/3 family. Mobile genetic elements such as transposons are important vehicles for the transmission of virulence and antibiotic resistance in many microorganisms.	2.55692e-64
NZ_CP036524.1|WP_040436081.1|3469708_3470542_-|transketolase	gnl|CDD|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	1.42511e-127
NZ_CP036524.1|WP_083790637.1|3447234_3447918_-|cysteine-rich-VLP-protein	gnl|CDD|372957	pfam14194, Cys_rich_VLP, Cysteine-rich VLP. This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is approximately 60 amino acids in length. It contains 6 conserved cysteines and a conserved VLP sequence motif.	2.58412e-29
NZ_CP036524.1|WP_040436078.1|3466746_3467400_-|DUF2291-domain-containing-protein	gnl|CDD|378370	pfam10054, DUF2291, Predicted periplasmic lipoprotein (DUF2291). Members of this family of hypothetical bacterial proteins have no known function.	8.09782e-73
NZ_CP036524.1|WP_149301989.1|3461164_3462646_-|glycerol-kinase-GlpK	gnl|CDD|198378	cd10427, FGGY_GK_1, Uncharacterized subgroup; belongs to the glycerol kinases subfamily of the FGGY family of carbohydrate kinases. This subgroup contains uncharacterized bacterial proteins belonging to the glycerol kinase subfamily of the FGGY family of carbohydrate kinases. The glycerol kinase subfamily includes glycerol kinases (GK; EC 2.7.1.30), and glycerol kinase-like proteins from all three kingdoms of living organisms. Glycerol is an important intermediate of energy metabolism and it plays fundamental roles in several vital physiological processes. GKs are involved in the entry of external glycerol into cellular metabolism. They catalyze the rate-limiting step in glycerol metabolism by transferring a phosphate from ATP to glycerol thus producing glycerol 3-phosphate (G3P) in the cytoplasm. Under different conditions, GKs from different species may exist in different oligomeric states. The monomer of GKs is composed of two large domains separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	0
NZ_CP036524.1|WP_006445107.1|3467588_3468617_-|D-ribose-ABC-transporter-substrate-binding-protein	gnl|CDD|380622	cd19967, PBP1_TmRBP-like, D-ribose ABC transporter substrate-binding protein such as Thermoanaerobacter tengcongensis ribose binding protein (ttRBP). Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs. Members of this group are belonging to the type 1 periplasmic binding protein superfamily, whose members are involved in chemotaxis, ATP-binding cassette transport, and intercellular communication in central nervous system. The thermophilic and mesophilic ribose-binding proteins are structurally very similar, but differ substantially in thermal stability.	1.30592e-125
NZ_CP036524.1|WP_006443229.1|3450239_3450734_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.1073e-21
NZ_CP036524.1|WP_006445103.1|3463621_3464023_-|D-ribose-pyranase	gnl|CDD|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	3.69274e-57
NZ_CP036524.1|WP_006445104.1|3464102_3465155_-|ABC-transporter-permease	gnl|CDD|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	6.79529e-82
NZ_CP036524.1|WP_147570498.1|3449631_3450129_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	7.13729e-19
NZ_CP036524.1|WP_006443223.1|3447051_3447183_-|hypothetical-protein	gnl|CDD|372961	pfam14202, TnpW, Transposon-encoded protein TnpW. This family of proteins is found in bacteria. Proteins in this family are typically between 54 and 75 amino acids in length. There is a single completely conserved residue G that may be functionally important.	4.26427e-10

Protein sequences

>NZ_CP036524.1|WP_040435059.1|3455434_3456232_-|transporter-substrate-binding-domain-containing-protein
MKMRRLSALLCGLLTLAAVLTGCGGREKSGTLRVGVRDDIMNFGYLNKETGRYYGMEIDLANKLAEKLGYEEVEFVTVQPDNRKEMLQEGKVDCLVAAYSIADTRKENFDFSPPYYTDETVIMAEKSALFHSADDLKDQTVGIVSGSNAGPLLAQKLYDLGIITDKVVSNTDTATVYEGAGVVKTAKYSDLDTALETGAVDAVCMDKCIAGTYMNENREFLDVVVAEQQYGVATRKDSDLSGPVADAVQKMLDDGTVERLIDKWD
>NZ_CP036524.1|WP_006443233.1|3452363_3455444_-|mechanosensitive-ion-channel
MGLGGIKLSEKLKRKALLAVGAEIICLVLLGLFLLSMQTDLSVNDQKKNTEDKVHEMSSLLKSAGEAADQITVSFDDIYRSKADSLSYMYQRQTADEYTDGRLEEYRSLLEVTNVLVVDSRGNKVALAQESPADFTRSRYNQLRTVFDTGEASEAFEVRNKETSLRYYGSRIDDDRMVVIEQDPEELYKLLEETSTWKSILGNVSVGLEGYAFAVSEKDYTFLYHPDEKLSGTDALDAGIPVEELEDNNYTWLTVNGEKFYCGITKQQDAYIICAVSEKEIISSRGVTVAGILFAFFAVMTLVITYSIFMMKDREKSGKKEAGSSAWGKFCYDRVIGRKIGTISVVGLIFILIITFYMQTLFALSRQSMGNNERVAEVEKTLKHYEKDIDETTEQYNARYLNKGRIASYIISQDPGVAQKDALVELSKALDVEAVNVFDMAGVQTATSSPYTNFKLSGDPEDQSYEFNKLLNGADYIIQDAQTDEVSGGYHQYIGVTLRDDRGDADGFVQISVTPSKLKETLSNMQIDKVLEKTKVGKGGFVFAVDKKDKTFAYYPKEKLTGRSAVSYGMQKQQFKDAYCDYITVDNKTYYGSSLETKSDYIYVVVPKDAMTGARLPITLACGAVSFICLLFVFLLLTLSRSGREEADAVKDGAGRRNIDVVMPDGSVRKTETAESRWETVSIRWNEKTPEQQISTVLKMILGVLAAAICMAVMMKEKIFGSNSIFLYILNGEWERGVNIFALTGCILIICVVSVITVLVQAILRMLSKTFGARGETVCRLLHSFIKYFSVIAILYYCLALIGVDTKTLLASAGILTLVVGLGARTLVSDILAGLFIIFEGEFRVGDIVTIGDWRGTVLEIGIRTTKIEDPSKNIKIISNSEVSGVINMTRQYSYSWADVGIEYGESLERVENILEKEFPNIRKRLTNIIEGPFYKGVIELGESSVVIRVMVLCTESDRVQMGRDLNREMKLIFDKYDINIPFPQVVVNEPTEAKKASEWEKRRADKFNRSQKELSKSFIAEEEEN
>NZ_CP036524.1|WP_040435058.1|3451552_3452245_-|aquaporin
MKKYVAEFIGTAVLTLFGCGSAAVSGGIDGTLGILGIAMAFGLSIVAMAYVIGDVSGCHINPAVSLGVFLNKGMSAADFAGYLVAQFLGGIAGAGILYGVISCTGLGPVWETGLGQNGFAEASYTGLSMPGAILVEVILTFVFVFTILGVTAKAENSRAAGIVIGLTLAFVHILGIPLTGTSVNPARSLGPALLVGNGTALSQVWVFIAAPLLGAVIAAVVYRTVCKREE
>NZ_CP036524.1|WP_006443229.1|3450239_3450734_+|GNAT-family-N-acetyltransferase
MILSTERLELVPLLPYQLRLWVEDIPKLEKDLKCSYQAEPMEGLFLEIVKGQLEKTEKNPNDFLWHSFWLLIRKSDRVVVGSADFKDTPNTDQEVEIGYGLGKDFERNGYMTEAVQAMCKWALEQENVSHVIAETDIDGFASQRILKRCGFIEKGQEKTIWWQL
>NZ_CP036524.1|WP_147570498.1|3449631_3450129_+|GNAT-family-N-acetyltransferase
MVEDDVDDLMEITNNPNVYQYVPPFLYKKSRGNLLAAIRNLGGRDFDKKKLIIAGIYLCDEPNKLIGLAELFDYKKRMNQITIGYRINESYWHRGIATDTVRLIMDYLCNDLGIQKLKAFVMPENVFSEKALTKNSFLKEPNTVQEKNWGGKEIVDLNVFTYAVL
>NZ_CP036524.1|WP_006443225.1|3448288_3448702_+|DUF3795-domain-containing-protein
MKMPTEKIDTAMFAPCGMNCLLCYKHCYHKKPCAGCLNSDMGKPEHCRKCKIKDCIKGKGLAYCFECPDYPCKLIKNLEKSYNKRYQASLMENSEFVRQHGLERFMEQQKGKYTCPKCGGIISIHDRECSECQESMK
>NZ_CP036524.1|WP_083790637.1|3447234_3447918_-|cysteine-rich-VLP-protein
MKKKLQPIERGPGGSLPRMTAAQRKRANALIRNTCCNYDNGNCLLLDDGDNCTCPQTISYSVCCIWFRRAVLPQDDFHAYMVEKYPDLERGESASKTGRKHIPTRLFKQAVSPSKQAGAIEAALDGINPLNAGKEKEDALSMLKKWFPLMENFSGQLKKYKATITDLLEENKKLEARAKASEKGKLKDTMERAKLESELHNIHRVLDRIPPEALAELKRQQHDRKER
>NZ_CP036524.1|WP_006443223.1|3447051_3447183_-|hypothetical-protein
MPPVTLQRRIGGTTYIVSSRFNERAKEDMVAKVKRLILSDSGQ
>NZ_CP036524.1|WP_006443222.1|3445662_3447027_-|DUF4368-domain-containing-protein
MITALYCRLSRDDELQGDSNSIVNQKEILWRYAEENHFPNPRFFVDDGYSGTNFDRPAYQEMMELVEDGMVEAIIVKDHSRLGRNRLVIGQLLEEILDEHNVRYIAVTDNIDSLKGLDDMVAVRDLFNEWYARDTSKKIRAVWRAKSSAGKRLCNNPPYGYRKDPEDKERWLVDEEAAKIVREIFSLCIAGVGPLQIAKRLRKEQVLNPTAYWEAHGLIVGNPTPADPYHWDNKAVAAILERMEYLGHTVNFKGTKKSYKSNTGTCSAHFIRAVVLEKLVLEHLQRTVQYVREYESEFVQSMGEKSAADRRKEISEKRRGLSQSQRRMEELDRLFQRLYEDNVAGKISDERFAKLSGGYEAEQKDLQEKVAILQAELTGQEEQAMNLDRFLAIVKKYTEIEKLPPTILNEFVEKIIVHAPDKSTGKRVQQVEISYNCVGMIELPDTNETNSKTA
>NZ_CP036524.1|WP_040435057.1|3443649_3445218_-|peptide-ABC-transporter-substrate-binding-protein
MKKRSWSGLLCLAMAAVMLAGCGGREKAGTSEPDKKTSGKNELVMGVSSSVTNLNKHLETMKEGWLMLGAVYDELYMKTDSETRYYLADSVELSDDGKTVTLKLKEDLKWHDGEPITADDVIFSLDVNADPDNGAGYANAVYIGDRPVSYKKADDLTVEITLPEPSASYVTILGTLPLLPAHVYGNDTDIKANSEANLKGIGSGPYKVKEFKNGECLELERFDDYYGDRPAIDKVVYKVIPDTSAQEVALQKGEINFMEVSSQAAADMYEGDKDITVHTFPEGRVNYLACNKFSDTFSDPKVKEAIYAALDGEEIVKGAYGADMGTAANTIFSNATQYHDKDIKGYEQDTGKAEKLVKETGLDGKTLKLVYNQDRAFMKETALIVQQQLKDVGIRLEVEGMESNGFFDRVFGDASDYDLYFNGYGAFGDPDEVISGMFDGTWGINLEVSEDQLDLWKQGRSAADDKERAGIYKELQEKAVEDMSIYPIAYPNYVFATSSSLEGADELQTNPVFEDYTKLSFK
>NZ_CP036524.1|WP_040436074.1|3460067_3460790_-|response-regulator-transcription-factor
MKIAVCEDNNKERKALCEQIKTAMARQDVEAEIEEFGTAEELLKAAKKIFFSMFFLDFLLPGISGMDAALKLRREGNYSPVVFTTVTKDYLSQSFSSVWAVHYLLKPVEQEGVDEAFFRALKVLEGAEKSLKIMVSRHFERIPYSDIYYIEGNNRNCIVHTRTGTYNPYESVQGMTEKLADSRFLRSHRSYVINLDHVIAVQRGKAVMRDDMLIPIRRGETELVRRAWEERKFEIVGRNA
>NZ_CP036524.1|WP_149301989.1|3461164_3462646_-|glycerol-kinase-GlpK
MSEKYIISIDQSTQGTKALLFDGSGSLIRRTDKPHRQIVNEKGWVSHDPEEIYHNTIEVVTRLVTESGIAKEQIAGVGISNQRETSLAWERSTGAPLGQAIVWQCARAADICERVEKLGAAEQIRARTGMNLSPYFPASKIAWILEHVDGAKEKAAAGDICHGTIDSWLIYRLTGRTSYKTDYSNASRTQFFNIFTLRWDEEICGLFGIDPANLAEVCDSNADFGETDFEGLLPRPVPIHGVLGDSHGSLFGQGCRKPGMIKSTYGTGSSIMMNIGEEPVLSTHGVVTSLAWSMSGKVNYVLEGNLNYTGAVITWLKDDLKLISSPQETEALAREAVKDDRLYLVPAFSGLGAPYWDSRAAAAIVGMTRTTGRAEVARAGVECIAYQITDIVKAMSEDAKVKVEELRVDGGPTRNSYLMQFQSDIAEAAVQVPDSEELSGIGPAYAAGLALGVWDERIFNKLKRVKYEPKMDGALRDRKYEGWKSAVSSVLTK
>NZ_CP036524.1|WP_006445102.1|3462659_3463544_-|ribokinase
MKVLNFGSLNLDYVYSVDHMVTPGETLASYGMNVFCGGKGLNQSIALAKAGVTVYHAGMIGEEGDILLKTCRDGGVKADYIRKIEGRSGHTIIQVDKTGQNCILLYGGANQSITKEYVDEVLAHFEKGDILLLQNEVNMLDYIIDSAYEKGLMIILNPSPYNSALDRCDFNKISMFLLNEIEGAQVTGEEDTDKILAKLKEIYPDAKVVLTLGGDGSVYQYKEEICRQGIFKVKAVDTTAAGDTFTGYFISSIIEGMSVPAGLELAARASAIAVSREGATASIPLKEEVLNTEL
>NZ_CP036524.1|WP_006445103.1|3463621_3464023_-|D-ribose-pyranase
MKKRGIINAQLAGLIAGLGHKDLFMIADGGMPIPKGVELVDLALCGGVPTYRQVMDAVLGETEVEAYTLAEEIVEKNPKLLAYIREKLPDADVEMISHVELKKMSGGIKFAVRTGEFTPYPNIILRAGVAFPA
>NZ_CP036524.1|WP_006445104.1|3464102_3465155_-|ABC-transporter-permease
MAAKQKSGNNKLMMTLLKGRTFIVLIILLIFFSITADNFLSAGALLTVAKHVALYGILAIGMTYVIITGGIDLSVGSVAGLAGMIAGGLIQEGLTLKMFGVTLYFSVPMIVLITVLLGALMGMINGLVITKCNVAPFIATLGTMYIWRGFANIRSNGATFSEISGSEGLGNTGFEVFGRNLGGTSIPCGVLILAIIAVVAGLILKKTPFGWHVLSIGGNEKASKLSGIKVDRVKIWVYAFSGFCSAVVGIIATSQLVSATPKTGESWEMNAIAASVLGGTSMAGGVGTIGGTIVGAFVIGVINDGMTMCGVTEFWQKIIRGLVIIIAVIIDQVQRNLQAKMALQARNENK
>NZ_CP036524.1|WP_006445105.1|3465158_3466715_-|sugar-ABC-transporter-ATP-binding-protein
MGETYKCRDDVFLHAEKISKIYPGTKALDEVSFDLLKGKVNVLIGENGAGKSTLMKMIAGIEQPNEGKMYIGDREVFFKNTTEARKHGIGIIHQELSLFPNLNVYQNIYMNKEKTKGKVALDNKTHMEGAKKVLERLEHPLDLHAKVGELRVGQQQMIEIARNLVEDDLKVLIMDEPTSSLSQQEVKVLFKIMRELTAAGISIVYISHRLEEIMEIGDHVTILRDGKYVADADVKEIDVPWIVHQMTGGAKSYPKRDREVDWNKVENVLEVKDLCLPKAGGGYLVDHLDFELKKGEVLGIYGLMGAGRSEVFECLMGLHPEHTGQVFMNGKELNIKSISQQIDNGFALIPEDRQAQGLVQTLDIEKNCALSALKRYKKGPFLDSKKEAEKVEQEIKDIQIKVADKKLPILSLSGGNQQKVVIGKGILTEPKILLMDEPSRGIDIGAKTEVFDIINKYAEEGLSIIVISSELQEIVSIADRVIVLSNGIKTGEFFGDEIQQDTLVLASYKGHHIEEKES
>NZ_CP036524.1|WP_040436078.1|3466746_3467400_-|DUF2291-domain-containing-protein
MKKRMIALALTLTLAASTLLTGCGIVKVVKIGEEGKYTGDVEFNAGDDVEAIWEESALPEMNENAVDLKEFLEESNGDLTALADEYGKYSMGDSGELSYVVKGSGTVEEVNTQSQAGYIAIKLDGYNGTEVIKIQIGPVYKGSSIRDSLSFIKFGDYKNQEQWAAVSQSINEVVAKDVVEPAKPDSLQGKTISFVGAFTVSTGSSDVLITPVVLEAE
>NZ_CP036524.1|WP_006445107.1|3467588_3468617_-|D-ribose-ABC-transporter-substrate-binding-protein
MKGFKKVLAMLLAVAMVGAMVMGCSSKSDDSSKKEDKKEDKKTEDTKDEEALPGGGSNIIYIITPSVSNPAFKAEADTATAKAKELGYEVKAASHDDDPTKQTELFDSAIADKAAAIICDNAGADATVEAVKKAREAGIPTFLIDREINEEGVAISQIVANNYQGAKAIAEKFVEAMGEKGKYVELLGKESDTNAGVRSSAFHEVIDQYPDMEMVAQQTANWEKTEAYDKMEAMLQANPDIEGVVCGNDTMLEGVCAALQAAGKTLPVIGVDGSDEAAALIKSGDATGTALQQFAVIAEMAVEQADKYLKEGSTGLDEKQLVDCIAITSENVDKLSGFVFTE
>NZ_CP036524.1|WP_149301990.1|3468786_3469716_-|transketolase-family-protein
MAKTANKQVMCEVLMEAAKKDKDVVALCSDSRGSASFTPFANELPDQFVETGIAEQNLVSISAGLAKCGKKPYAASPACFLSTRSYEQCKIDVAYSNTNVKLIGISGGVSYGALGMSHHSAQDIAAMAAVPNMRVYLPSDRLQTECLTRALLADDKPAYIRVGRNAVDDVYEEGNVPFEMDKATFVTEGSDVAVIACGEMVKPAADAAAKLKEEGISVTVVDMYCVKPLDKEAVVKAAQNAKAVVTVEEHAPYGGLGSMVSQVVGSECPKKVVNLSLPDAPVITGTSKEVFQYYGLDAEGIIKTIKEVL
>NZ_CP036524.1|WP_040436081.1|3469708_3470542_-|transketolase
MSNLKALAYGLRETVIDMIVEGKAGHIGGDMSVLEILTELYFCQMNISPENQDDPDRDKFVMSKGHSVEAYYAVLAEKGFFDKKELISTFSKFGSKFIGHPNNKLPGVEMNSGSLGHGLPVCVGMALAGKMNGQDYRVYTVMGDGELAEGSVWEGAMAACQYKLDNLCAVVDRNRLQISGNTEDVMGHDDLHERFGAFGWHVIDVADGNDIDQLHAAFEEAKTVKGQPTVLIANTVKGKGSSVMENKANWHHKVPNEEELAQIRKDLAERKEAALHG

Crispr_ID: NZ_CP036524_8

• CRISPR_ID: NZ_CP036524_8
• CRISPR_location: 3479331-3479426
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP036524_8

Consensus_repeat	Method
AGGCTGGTGCAGTTAGAAAACGCTTGG	CRISPRCasFinder

spacers of NZ_CP036524_8

>8.1|3479358|42|NZ_CP036524|CRISPRCasFinder
GCTCCAACGGTTTCCAGGTTCTTTGGGAAGGTAACCTCTGTA

CRISPR arrays and Neighbor proteins around NZ_CP036524_8

CRISPR arrays

The CRISPR arrays of NZ_CP036524_8

>merge|NZ_CP036524|8|3479331-3479426|CRISPRCasFinder
AGGCTGGTGCAGTTAGAAAACGCTTGGGCTCCAACGGTTTCCAGGTTCTTTGGGAAGGTAACCTCTGTAAGGCTGGGGCAGTTAGAAAACGCTTGG

>NZ_CP036524|8|7|3479331-3479426|CRISPRCasFinder
AGGCTGGTGCAGTTAGAAAACGCTTGG	GCTCCAACGGTTTCCAGGTTCTTTGGGAAGGTAACCTCTGTA
AGGCTGGGGCAGTTAGAAAACGCTTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006443247.1|3489067_3490390_-|allantoinase-AllB	unknown	unknown	gnl|CDD|238640
NZ_CP036524.1|WP_006445107.1|3467588_3468617_-|D-ribose-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380622
NZ_CP036524.1|WP_006443241.1|3483284_3483800_-|transcription-termination/antitermination-factor-NusG	unknown	unknown	gnl|CDD|180161
NZ_CP036524.1|WP_006443244.1|3485129_3485879_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|225070
NZ_CP036524.1|WP_006445113.1|3470544_3471945_-|L-fucose/L-arabinose-isomerase-family-protein	unknown	unknown	gnl|CDD|238323
NZ_CP036524.1|WP_005332089.1|3484049_3484199_-|50S-ribosomal-protein-L33	unknown	unknown	gnl|CDD|234783
NZ_CP036524.1|WP_149301990.1|3468786_3469716_-|transketolase-family-protein	unknown	unknown	gnl|CDD|226467
NZ_CP036524.1|WP_006443246.1|3487446_3489063_-|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377939
NZ_CP036524.1|WP_040436081.1|3469708_3470542_-|transketolase	unknown	unknown	gnl|CDD|238970
NZ_CP036524.1|WP_006443243.1|3484392_3485133_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|225070
NZ_CP036524.1|WP_006445121.1|3476650_3477988_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|340412
NZ_CP036524.1|WP_006445118.1|3474987_3475563_-|50S-ribosomal-protein-L10	unknown	unknown	gnl|CDD|234632
NZ_CP036524.1|WP_040435060.1|3482027_3482720_-|50S-ribosomal-protein-L1	unknown	unknown	gnl|CDD|180071
NZ_CP036524.1|WP_006445117.1|3474580_3474955_-|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl|CDD|234671
NZ_CP036524.1|WP_006445120.1|3475925_3476654_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225818
NZ_CP036524.1|WP_006443245.1|3485947_3487432_-|amidohydrolase	unknown	unknown	gnl|CDD|238623
NZ_CP036524.1|WP_006443239.1|3482802_3483228_-|50S-ribosomal-protein-L11	unknown	unknown	gnl|CDD|234661
NZ_CP036524.1|WP_006445116.1|3473439_3474438_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380500
NZ_CP036524.1|WP_006443242.1|3483833_3484028_-|preprotein-translocase-subunit-SecE	unknown	unknown	gnl|CDD|376355
NZ_CP036524.1|WP_006445114.1|3471980_3472988_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380500

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006443247.1|3489067_3490390_-|allantoinase-AllB	gnl|CDD|238640	cd01315, L-HYD_ALN, L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in biotechnology). But L-HYDs differ by having an L-enantio specificity and by lacking activity on possible natural substrates such as dihydropyrimidines. Allantoinase catalyzes the hydrolytic cleavage of the five-member ring of allantoin (5-ureidohydantoin) to form allantoic acid.	5.23191e-152
NZ_CP036524.1|WP_006445107.1|3467588_3468617_-|D-ribose-ABC-transporter-substrate-binding-protein	gnl|CDD|380622	cd19967, PBP1_TmRBP-like, D-ribose ABC transporter substrate-binding protein such as Thermoanaerobacter tengcongensis ribose binding protein (ttRBP). Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs. Members of this group are belonging to the type 1 periplasmic binding protein superfamily, whose members are involved in chemotaxis, ATP-binding cassette transport, and intercellular communication in central nervous system. The thermophilic and mesophilic ribose-binding proteins are structurally very similar, but differ substantially in thermal stability.	1.30592e-125
NZ_CP036524.1|WP_006443241.1|3483284_3483800_-|transcription-termination/antitermination-factor-NusG	gnl|CDD|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	1.14346e-76
NZ_CP036524.1|WP_006443244.1|3485129_3485879_-|amidohydrolase-family-protein	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	1.27553e-31
NZ_CP036524.1|WP_006445113.1|3470544_3471945_-|L-fucose/L-arabinose-isomerase-family-protein	gnl|CDD|238323	cd00578, L-fuc_L-ara-isomerases, L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose in glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in various oligo- and polysaccharides in mammals, bacteria and plants. AI catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion to D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon source. AI can also convert D-galactose to D-tagatose at elevated temperatures in the presence of divalent metal ions. D-tagatose, rarely found in nature, is of commercial interest as a low-calorie sugar substitute.	5.78146e-111
NZ_CP036524.1|WP_005332089.1|3484049_3484199_-|50S-ribosomal-protein-L33	gnl|CDD|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	5.8632e-16
NZ_CP036524.1|WP_149301990.1|3468786_3469716_-|transketolase-family-protein	gnl|CDD|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	3.88309e-115
NZ_CP036524.1|WP_006443246.1|3487446_3489063_-|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	4.65228e-28
NZ_CP036524.1|WP_040436081.1|3469708_3470542_-|transketolase	gnl|CDD|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	1.42511e-127
NZ_CP036524.1|WP_006443243.1|3484392_3485133_-|amidohydrolase-family-protein	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	9.72181e-32
NZ_CP036524.1|WP_006445121.1|3476650_3477988_+|sensor-histidine-kinase	gnl|CDD|340412	cd16935, HATPase_AgrC-ComD-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.	4.86492e-38
NZ_CP036524.1|WP_006445118.1|3474987_3475563_-|50S-ribosomal-protein-L10	gnl|CDD|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	4.84521e-64
NZ_CP036524.1|WP_040435060.1|3482027_3482720_-|50S-ribosomal-protein-L1	gnl|CDD|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	3.74354e-143
NZ_CP036524.1|WP_006445117.1|3474580_3474955_-|50S-ribosomal-protein-L7/L12	gnl|CDD|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	1.8946e-45
NZ_CP036524.1|WP_006445120.1|3475925_3476654_+|response-regulator-transcription-factor	gnl|CDD|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	3.45448e-30
NZ_CP036524.1|WP_006443245.1|3485947_3487432_-|amidohydrolase	gnl|CDD|238623	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are catalyzed by atrazine chlorohydrolase (AtzA), hydroxyatrazine ethylaminohydrolase (AtzB), and N-isopropylammelide N-isopropylaminohydrolase (AtzC). All three enzymes belong to the superfamily of metal dependent hydrolases. AtzA and AtzB, beside other related enzymes are represented in this CD.	2.86863e-114
NZ_CP036524.1|WP_006443239.1|3482802_3483228_-|50S-ribosomal-protein-L11	gnl|CDD|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	4.38428e-94
NZ_CP036524.1|WP_006445116.1|3473439_3474438_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380500	cd06277, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	8.33773e-105
NZ_CP036524.1|WP_006443242.1|3483833_3484028_-|preprotein-translocase-subunit-SecE	gnl|CDD|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	1.39251e-12
NZ_CP036524.1|WP_006445114.1|3471980_3472988_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380500	cd06277, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.52437e-99

Protein sequences

>NZ_CP036524.1|WP_006445121.1|3476650_3477988_+|sensor-histidine-kinase
MTQDIIISALLFILPCILILFLTFSDHLRTPTHATAAFSISCFMIIDMAATYIYYTKPLTAWTMILLSFAAMLAGVVLFRAASGYSFAQSLFSVAIVMCYTDSIYIFSSQFHYIAAGRLPDGPSALHTVSTLVISLATFPFVLLLFKRLLRPALDATESLAFWRISWGIPLCSRLLYYLTIFPIFSPNLPTSVQSDIYSAPTLWSIFTFFTYVIALKMVTETTKNARLQEELHISETQFAAQLKQSEMIQQRIEETMRIRHDFRHTLIALQACLDSKDYDGMGEFINNYICSLDSLRPTAYCDNPVVNAIISYYAEMARGDGITFSASVQLEQKLPLTDTDACIILGNLLENALEACQRQTGTGRYIHVKLHAVHGSSLVIIIDNSYSGIIHKKEHVFLSTKAKNRKGIGIASVLDIVSKYEGVPRFEYDAETFKVSIFLHHSRN
>NZ_CP036524.1|WP_006445120.1|3475925_3476654_+|response-regulator-transcription-factor
MNVAVVDDSLFDRQYLQDNIERYCSEHKVHMQIKTYDNGHGFLNSFSVHTYDLVFLDIFMDETSGIHIAEKIRQIDDRCQIIFTTSSQEHAIKAFRLHALDYLLKPYTYEQLEESLFRCQTAMKRFSHYIELKEGRHYTRVLISDIIYTDYYNHYIQVHTLRNVIRSYMSFADFAPMLGKYPQFLWCYRNCMVNMDYIRSMDSKDFILSTDERIPISRARKNEIRQTYANYLFEYVTTGDTP
>NZ_CP036524.1|WP_006445118.1|3474987_3475563_-|50S-ribosomal-protein-L10
MAKVELKQPIVETIADEVKDAASVVLVDYRGLTVAQDTELRKQLRDAGIIYKVYKNTMMKRAFEGTEYAALEEHLAGPSAIAISKEDATAPARILCKFAKDAKALELKAGVIEGSVYDTAGLTELSKIPSREELLSKLLGSLQSPITNFARVIKQIAEQGGEVAAEEAPASEEAPAAAEAPAEETAEATEE
>NZ_CP036524.1|WP_006445117.1|3474580_3474955_-|50S-ribosomal-protein-L7/L12
MAKITTAEMIEAIKELSVLELNELVKACEEEFGVSAAAGVVVAAAGGEAAAAEEKDEFDVELVSAGSSKVKVIKVVREITGLGLKEAKELVDGAPKVVKEGASKAEAEEIKAKLEGEGAEVNLK
>NZ_CP036524.1|WP_006445116.1|3473439_3474438_-|LacI-family-DNA-binding-transcriptional-regulator
MKVSVRKISEITGFSPATVSNALNHKKGVNKETADRILKTAEELGYRLEEKISKIRFVIFRRNGLIIDDSPFHPAVIEGVERQAKSLGYETVFNHVDINDIEYNTQLQEILSDVESAIVLLGTEMQEEDFEPYTHAKNKIILLDGWSDRYFFDSVLISNTDSAARAVEYLIDKGHRDIGYLRGDFRIQAFCYREIGYRRVMDRHHLPVQPEYIATVGTKIETAYEGMRKYLEETPILPTAFFADNDTIAIGAMQALKERGYDIPGDVSIIGFDNISFGAISDPPLTTIHVYKHEMGEMAVRELMRSVEDGKKIKTKIQVCTDFVERASVRKI
>NZ_CP036524.1|WP_006445114.1|3471980_3472988_-|LacI-family-DNA-binding-transcriptional-regulator
MKVSIKKISQITGFSPATVSNALNRKKGVNPVTSEKILKAAETLGYQQGKTITKIKFVTYRKNGLIIDDSQIFPAMIEGVERQAKELGYETTFCHLNYEDESFEIRLKEFLEDTNCLVILLGTEMTEEDYVPFYDYKGYLIVLDGWSDEMIFDGIMINNTDAVCNAMEYLVEKGHREIGYLRGDYRIKSFRYREYGYHRVMGRHRLVRKPEYEVTVGTKLESAYQDMKKYLEHTDRLPTAFFADNDVIAIGAMRAMKEKGIRIPEDISIVGFDDIRFGTVSTPGLTTVRVFKQEMGEVAVRRALDHIKYSGKDIKMKIQVCTQFIERDSVRQIER
>NZ_CP036524.1|WP_006445113.1|3470544_3471945_-|L-fucose/L-arabinose-isomerase-family-protein
MATIKLGFAPTRRSIFSAPDAIKYRGLTADRLRELGIDFVDIDDINEEGLLYDDNDVKKIAAKFKKEGVDGIMFPHCNFGTEYVCARLAKEMDVPVMLWGPLDERPEENGVRLRDTQCGLFATGKVLRRFQIPFTYVTNCRLNDPVFERGLRDFMAVCNVVKTFRNIRILQISTRPFDFWTTMCNEGELLEKFNVQLAPVPMTELTQEVKAVKEEGGRLAEMISYIRENMEVKIKDNEVENVAALAVAMERLVEKYGCGAAAIQCWNALQTELGVMPCAANAILNDKGIPVVCETDIHGAITALMVEAAGMGETRGFFADWTIRHPDIENGELLQHCGPWPISVAKEKPQLTYPLAFDHPGSLTAEAKHGDVTLCRFDGDNGEYSLLLGNAKGVDGPKGMGTYLWVEVENIKRLEAKIVEGPYIHHCVGIHKDIVPVLYEACKYIGVKPDFYDPIEEDVKAYLRGE
>NZ_CP036524.1|WP_040436081.1|3469708_3470542_-|transketolase
MSNLKALAYGLRETVIDMIVEGKAGHIGGDMSVLEILTELYFCQMNISPENQDDPDRDKFVMSKGHSVEAYYAVLAEKGFFDKKELISTFSKFGSKFIGHPNNKLPGVEMNSGSLGHGLPVCVGMALAGKMNGQDYRVYTVMGDGELAEGSVWEGAMAACQYKLDNLCAVVDRNRLQISGNTEDVMGHDDLHERFGAFGWHVIDVADGNDIDQLHAAFEEAKTVKGQPTVLIANTVKGKGSSVMENKANWHHKVPNEEELAQIRKDLAERKEAALHG
>NZ_CP036524.1|WP_149301990.1|3468786_3469716_-|transketolase-family-protein
MAKTANKQVMCEVLMEAAKKDKDVVALCSDSRGSASFTPFANELPDQFVETGIAEQNLVSISAGLAKCGKKPYAASPACFLSTRSYEQCKIDVAYSNTNVKLIGISGGVSYGALGMSHHSAQDIAAMAAVPNMRVYLPSDRLQTECLTRALLADDKPAYIRVGRNAVDDVYEEGNVPFEMDKATFVTEGSDVAVIACGEMVKPAADAAAKLKEEGISVTVVDMYCVKPLDKEAVVKAAQNAKAVVTVEEHAPYGGLGSMVSQVVGSECPKKVVNLSLPDAPVITGTSKEVFQYYGLDAEGIIKTIKEVL
>NZ_CP036524.1|WP_006445107.1|3467588_3468617_-|D-ribose-ABC-transporter-substrate-binding-protein
MKGFKKVLAMLLAVAMVGAMVMGCSSKSDDSSKKEDKKEDKKTEDTKDEEALPGGGSNIIYIITPSVSNPAFKAEADTATAKAKELGYEVKAASHDDDPTKQTELFDSAIADKAAAIICDNAGADATVEAVKKAREAGIPTFLIDREINEEGVAISQIVANNYQGAKAIAEKFVEAMGEKGKYVELLGKESDTNAGVRSSAFHEVIDQYPDMEMVAQQTANWEKTEAYDKMEAMLQANPDIEGVVCGNDTMLEGVCAALQAAGKTLPVIGVDGSDEAAALIKSGDATGTALQQFAVIAEMAVEQADKYLKEGSTGLDEKQLVDCIAITSENVDKLSGFVFTE
>NZ_CP036524.1|WP_040435060.1|3482027_3482720_-|50S-ribosomal-protein-L1
MKRGKKYIEAAKVIDRGNLYDKEEAVSLVKKTAVAKFDETIEAHIRTGCDGRHADQQIRGAVVLPHGTGKKTRILVFAKDAKAEEAKAAGADYVGADELIPKIQNENWFEFDVVVATPDMMGVVGRLGRVLGPKGLMPNPKAGTVTMDVAKAVQEIKAGKIEYRLDKTNIIHVPVGKASFTEEQLADNFQTLIDAINKAKPAAVKGQFLKSVTLTSTMGPGVKINPAKLV
>NZ_CP036524.1|WP_006443239.1|3482802_3483228_-|50S-ribosomal-protein-L11
MAKKVEGYIKLQIPAGKATPAPPVGPALGQHGVNIVEFTKQFNAKTADQGDMIIPVVITVYNDRSFSFITKTPPAAVLIKKACNIKSGSGVPNKTKVATITKAQLQEIAELKMPDLNAATVEAAMSMIAGTCRSMGVKVEE
>NZ_CP036524.1|WP_006443241.1|3483284_3483800_-|transcription-termination/antitermination-factor-NusG
MSEAKWYVVHTYSGYENKVKANIDKTIENRHLEDQILEVRVPMQDVVELKNGVQKATQKKMFPGYVLIHMIMNDDTWYVVRNTRGVTGFVGPGSKPVPLTDAEMAPLGIRQENIVVDFEVGDTVQVIAGAWADTVGVIQALNIPKQSLTINVELFGRETPVEISFAEVKKM
>NZ_CP036524.1|WP_006443242.1|3483833_3484028_-|preprotein-translocase-subunit-SecE
MAEQKTQKKSWFKGLKAEFRKIIWPDKMTLAKQTAAVVSVSVVLGLIIAVIDFLVQNGVDLLVR
>NZ_CP036524.1|WP_005332089.1|3484049_3484199_-|50S-ribosomal-protein-L33
MRTRITLECTECKQRNYNMTKDKKTHPERMETKKYCKFCKSHTLHKETK
>NZ_CP036524.1|WP_006443243.1|3484392_3485133_-|amidohydrolase-family-protein
MIIDFHTYVGTSMLGQESTEDELLQNMAENQVDISVICPVKTTDPFFERQNEYVSDLQRKHAGKLAGFCRIDPNLGKDSEKILRESVQELELKGLVLHPWEETFAINDKKVYPFMEICREYGLPVLVETGYPWLSHCFQVADLAERFPEITFIMSHGGQFDSSGYALTDVDHVMDRHSNLMIETSGDYSDEGIENIPERLGYDRLVFGSHFPWLNTELEIYRIQRADLTDEARESIFYKNALRLLK
>NZ_CP036524.1|WP_006443244.1|3485129_3485879_-|amidohydrolase-family-protein
MRIIDMHAHVDVCEPLHWHDTATKLVKLMDEAGIEKAVVSAYLNLPGPDMTCAERLWNSIEPYKERFMMFLRMDPWFGQEAVDFLEESCRTYPVRGVKLHPAHYTLHPYGELTVNLCRKAGELGLPVLFHCGDEMMCLPLQIGELAAQCPDTVIILAHMGGYAHNRDAIEAAKKYKNIYIDTSEVPLVKEIRWFVDELGAERIFFGTDAPCCDPLVELKKVLLAGLSEEELEMVLYKNAVRVMGLEGEK
>NZ_CP036524.1|WP_006443245.1|3485947_3487432_-|amidohydrolase
MKILLKNAKILTFDPEDKILERADLLIEGRKITRIGYRIEESADKIIDCTDKLVMPGLVNAHLHSDENMFRGRFDNLPLEPWMLYSCPPLDYGPFSHRLIYLRTMIGAMEMVKKGITCVQDDVSECPKATVKGYDQVFQAYKDIGLKGNIAVNMGDRAFMDRLPYTKDCIPGQYHGLLSSHPDPDEMIETYEEVIRRWDRKDGMRVVFSTSAPQRCTDEYLMRGLKTALKYDLPMHTHILETRMQRATGPEFYGASIVKHIKDIGFLTDRLTIIHGVWMDEEDMRMIGEAGASVAHNPVSNLKLGSGIMPLRRMVQNNVNVVLGTDGMSSNDGYSMFETVKFAALLQKVMDADYKTWLDARSILKMAIQTPAHSLRRTEEMGSLEEGKDADIAVINLKSEAFTPLNDIYKHLVYCEDGSDVETVISAGRILMENRNILNVDENALIEELQAMTGEFQERFKDTVEKNDALMPYVDRIYEKCIRQYEDCTCNLFV
>NZ_CP036524.1|WP_006443246.1|3487446_3489063_-|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MKSSLEWLVTASGLKNIKCIACDDLTNTRFDGVTVLDNPDAIRWVKQDELAVTTGYFLLHDEEAQKRIVRELKEAGCAGLGVKIRDYFQEIPEGMVKEAEKVKLPLLELPFYYSLSEVSQTIYNHIYELSYRSRVKEQKLIEDISDIFFSKRGTMEIVYRIAEFLKRTVILLDSDFKCVYAAKRMNDKKLCMKDSVIRRLKSLKNDECVFLFPDKTERKGYTVTIPGAGANALLLVLEDAGELTKEEKSIIERCIKILSMALEQARSRQEDRYEFEDSYHKDLYEYLNGLRQYDDGELKNILRDIEMPFEKKRIMILLQIQGGFDAGTDYRELIQGCIRKCKEMRGFEPYILSRGRKFIVYLFACTDKSDPFMCSAAGKLADIMAERMGRINDGMEVQIGIGKSSDDFPGIKRAYQEAEKAVDIGEKLGMKEQVFAYNQLEFYDYLLQYPVKTKEQCCDSIRCLQEYDEENNTELVHTLLGFLEHKFNVSETAKALYIHRNTLINRLNKIKELLYNDLETMDDLMPLCMEAYAYKLFS
>NZ_CP036524.1|WP_006443247.1|3489067_3490390_-|allantoinase-AllB
MYDLAIEKGYVITAAGKRRLDIGISNGIIAGLSMPGMLGAAKESVQVPGRYIFPGGIDVHVHMDDLGADEPEDWRHGSMAAAAGGITTVADMPIDNVPATVDRRSLQMKLMRIKGNSFTDYMVWGGLTADNLDAVMPMLSEGAAGLKAFLCDSGAEDFPRVSDPVLLEAMRLAAKENFPIVIHAENEEINNYYSKKLKGRLRWEDWSRMHPEESELEAVARCALFARITGAGVHIAHISSAKSIALIQEARRQGARITCETCPHYLMFSEEDYPDKGAMLKCAPPVRGMRNRDALWEELKCGHIDIISSDHSPSADKSVTDAVDRAWAGISGVQFTLPVLFSEGCCKRKMPPERIAEVLSLRPAELLGIDKSKGSIELGKDADLAVLNPEKQTIYDENQIKTKVKNSVYKDMCLQGTVERTFLRGAEAGGSKPRGRYICR

Crispr_ID: NZ_CP036524_9

• CRISPR_ID: NZ_CP036524_9
• CRISPR_location: 3560931-3561066
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP036524_9

Consensus_repeat	Method
GCGGGCTGGCGCCCTGCAGCTTCACTTGCTTGACGGGGCGCTGGCA	CRISPRCasFinder

spacers of NZ_CP036524_9

>9.1|3560977|44|NZ_CP036524|CRISPRCasFinder
GGGGGACGCCGTGCCAGTTCTGTTCCGTCTCGCTTCATTTTGCT

CRISPR arrays and Neighbor proteins around NZ_CP036524_9

CRISPR arrays

The CRISPR arrays of NZ_CP036524_9

>merge|NZ_CP036524|9|3560931-3561066|CRISPRCasFinder
GCGGGCTGGCGCCCTGCAGCTTCACTTGCTTGACGGGGCGCTGGCAGGGGGACGCCGTGCCAGTTCTGTTCCGTCTCGCTTCATTTTGCTGCGGGCTGGCGCCCTGCAGCTTCACTTGCTTGACGGGGTGCTGGCA

>NZ_CP036524|9|8|3560931-3561066|CRISPRCasFinder
GCGGGCTGGCGCCCTGCAGCTTCACTTGCTTGACGGGGCGCTGGCA	GGGGGACGCCGTGCCAGTTCTGTTCCGTCTCGCTTCATTTTGCT
GCGGGCTGGCGCCCTGCAGCTTCACTTGCTTGACGGGGTGCTGGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP036524.1|WP_006443316.1|3558918_3559419_-|shikimate-kinase	unknown	unknown	gnl|CDD|234654
NZ_CP036524.1|WP_040435085.1|3556139_3557357_-|MFS-transporter	unknown	unknown	gnl|CDD|340911
NZ_CP036524.1|WP_006443312.1|3554646_3555834_-|methionine-adenosyltransferase	unknown	unknown	gnl|CDD|235374
NZ_CP036524.1|WP_006443331.1|3570005_3570890_-|hypothetical-protein	unknown	unknown	gnl|CDD|100037
NZ_CP036524.1|WP_006443327.1|3568857_3569166_-|hypothetical-protein	unknown	unknown	gnl|CDD|349951
NZ_CP036524.1|WP_006443323.1|3564678_3565647_-|V-type-ATPase-subunit	unknown	unknown	gnl|CDD|376708
NZ_CP036524.1|WP_006443326.1|3566800_3568819_-|V-type-ATP-synthase-subunit-I	unknown	unknown	gnl|CDD|235600
NZ_CP036524.1|WP_006443308.1|3550082_3550733_-|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223643
NZ_CP036524.1|WP_006443321.1|3562571_3564338_-|V-type-ATP-synthase-subunit-A	unknown	unknown	gnl|CDD|235248
NZ_CP036524.1|WP_006443325.1|3566315_3566801_-|V-type-ATP-synthase-subunit-K	unknown	unknown	gnl|CDD|235830
NZ_CP036524.1|WP_006443309.1|3550782_3552162_-|potassium-transporter-KtrB	unknown	unknown	gnl|CDD|273349
NZ_CP036524.1|WP_006443322.1|3564365_3564686_-|V-type-ATP-synthase-subunit-F	unknown	unknown	gnl|CDD|179293
NZ_CP036524.1|WP_006443329.1|3569327_3569819_-|tRNA-(cytidine(34)-2'-O)-methyltransferase	unknown	unknown	gnl|CDD|349967
NZ_CP036524.1|WP_006443324.1|3565680_3566274_-|hypothetical-protein	unknown	unknown	gnl|CDD|224308
NZ_CP036524.1|WP_006443317.1|3559542_3559899_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP036524.1|WP_006443320.1|3561194_3562568_-|V-type-ATP-synthase-subunit-B	unknown	unknown	gnl|CDD|235251
NZ_CP036524.1|WP_040435084.1|3553071_3554568_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP036524.1|WP_006443310.1|3552389_3553079_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP036524.1|WP_040435086.1|3560216_3560876_-|V-type-ATP-synthase-subunit-D	unknown	unknown	gnl|CDD|178991
NZ_CP036524.1|WP_006443315.1|3557466_3558759_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP036524.1|WP_006443316.1|3558918_3559419_-|shikimate-kinase	gnl|CDD|234654	PRK00131, aroK, shikimate kinase; Reviewed.	1.0936e-55
NZ_CP036524.1|WP_040435085.1|3556139_3557357_-|MFS-transporter	gnl|CDD|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.74796e-68
NZ_CP036524.1|WP_006443312.1|3554646_3555834_-|methionine-adenosyltransferase	gnl|CDD|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_CP036524.1|WP_006443331.1|3570005_3570890_-|hypothetical-protein	gnl|CDD|100037	cd06061, PurM-like1, AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.	3.36447e-51
NZ_CP036524.1|WP_006443327.1|3568857_3569166_-|hypothetical-protein	gnl|CDD|349951	cd06503, ATP-synt_Fo_b, F-type ATP synthase, membrane subunit b. Membrane subunit b is a component of the Fo complex of FoF1-ATP synthase. The F-type ATP synthases (FoF1-ATPase) consist of two structural domains: the F1 (assembly factor one) complex containing the soluble catalytic core, and the Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F1 is composed of alpha (or A), beta (B), gamma (C), delta (D) and epsilon (E) subunits with a stoichiometry of 3:3:1:1:1, while Fo consists of the three subunits a, b, and c (1:2:10-14). An oligomeric ring of 10-14 c subunits (c-ring) make up the Fo rotor. The flux of protons through the ATPase channel (Fo) drives the rotation of the c-ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the c-ring of Fo. The F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. The F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. This group also includes F-ATP synthase that has also been found in the archaea Candidatus Methanoperedens.	0.000830144
NZ_CP036524.1|WP_006443323.1|3564678_3565647_-|V-type-ATPase-subunit	gnl|CDD|376708	pfam01992, vATP-synt_AC39, ATP synthase (C/AC39) subunit. This family includes the AC39 subunit from vacuolar ATP synthase, and the C subunit from archaebacterial ATP synthase. The family also includes subunit C from the Sodium transporting ATP synthase from Enterococcus hirae.	1.93572e-67
NZ_CP036524.1|WP_006443326.1|3566800_3568819_-|V-type-ATP-synthase-subunit-I	gnl|CDD|235600	PRK05771, PRK05771, V-type ATP synthase subunit I; Validated.	1.28424e-145
NZ_CP036524.1|WP_006443308.1|3550082_3550733_-|TrkA-family-potassium-uptake-protein	gnl|CDD|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	1.38453e-52
NZ_CP036524.1|WP_006443321.1|3562571_3564338_-|V-type-ATP-synthase-subunit-A	gnl|CDD|235248	PRK04192, PRK04192, V-type ATP synthase subunit A; Provisional.	0
NZ_CP036524.1|WP_006443325.1|3566315_3566801_-|V-type-ATP-synthase-subunit-K	gnl|CDD|235830	PRK06558, PRK06558, V-type ATP synthase subunit K; Validated.	5.30375e-56
NZ_CP036524.1|WP_006443309.1|3550782_3552162_-|potassium-transporter-KtrB	gnl|CDD|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	1.83042e-83
NZ_CP036524.1|WP_006443322.1|3564365_3564686_-|V-type-ATP-synthase-subunit-F	gnl|CDD|179293	PRK01395, PRK01395, V-type ATP synthase subunit F; Provisional.	3.02496e-39
NZ_CP036524.1|WP_006443329.1|3569327_3569819_-|tRNA-(cytidine(34)-2'-O)-methyltransferase	gnl|CDD|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	1.88355e-88
NZ_CP036524.1|WP_006443324.1|3565680_3566274_-|hypothetical-protein	gnl|CDD|224308	COG1390, NtpE, Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion].	1.77302e-10
NZ_CP036524.1|WP_006443320.1|3561194_3562568_-|V-type-ATP-synthase-subunit-B	gnl|CDD|235251	PRK04196, PRK04196, V-type ATP synthase subunit B; Provisional.	0
NZ_CP036524.1|WP_040435084.1|3553071_3554568_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.0489e-60
NZ_CP036524.1|WP_006443310.1|3552389_3553079_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.02721e-88
NZ_CP036524.1|WP_040435086.1|3560216_3560876_-|V-type-ATP-synthase-subunit-D	gnl|CDD|178991	PRK00373, PRK00373, V-type ATP synthase subunit D; Reviewed.	3.77155e-81
NZ_CP036524.1|WP_006443315.1|3557466_3558759_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0

Protein sequences

>NZ_CP036524.1|WP_040435086.1|3560216_3560876_-|V-type-ATP-synthase-subunit-D
MASTQVTPTRMELTKTKKKLVTAVKGHKLLKDKRDELMRQFLDLVRENMELRLKVEAGIRSANKNFVIAKAGMDEATLNTALMAPKQEVNLEVDKKNVMSVNIPVFETKTRTADANDIYSYGFAFTSSDLDGAVKSLADILPDMLKLAETEKACQLMAVEIEKTRRRVNALEHVIIPEAQKNIKYITMKLDENERSSQIRLMKVKDMMLEEAHHYSEKA
>NZ_CP036524.1|WP_006443317.1|3559542_3559899_-|hypothetical-protein
MDNRLPYYMAYPMPLLYDDDKVARRDLDYMKSLYPAAAKRLIPYIEDECDRLEYEGSMMYDEYPDQLQLRLMCRRIYDRAEEDEEVPGKWLHDLIQVMAYQELCRRRCEHRNMRRKYY
>NZ_CP036524.1|WP_006443316.1|3558918_3559419_-|shikimate-kinase
MENIIFIGMPAVGKSTVGVVVAKRLGYQFIDTDLLIQEKEGKLLREIIEKKGIDGFLEVEDRVNAEVEADNTVISPGGSVVYCKNAMKHYKEIGTVVYLKASYETINKRLKSAKNRGVVLRDGQTLRHLYDERVPLFEKYADITVCEDGLKLEDTIEKVIGALQSA
>NZ_CP036524.1|WP_006443315.1|3557466_3558759_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEQYIIKGGHPLVGEVEIGGAKNAALAILAAAIMTDDTVLIDNIPDVNDVNVLLDAITGIGAKVHRVDRHTVKINGSGIRNYDVEYDYIKKIRASYYLLGALLGKYKRAEVALPGGCNIGSRPIDQHLKGFRALGADVDIEHGKVVAEAEKLVGRHVYFDVVTVGATINVMMAATMAEGITIMENVAKEPHVVDVANFLNSMGANIRGAGTDVIKIRGVHRLHGTEYSVIPDQIEAGTFMFAAAATKGDVTVLNVIPKHLEATIAKLTEIGCEVEEFDDAVRVVSKGDLTSTHVKTLPYPGFPTDMQPQIGVTLALCKGTSTITESIFENRFKYLDELARMGANIKVEGNSATIEGVEQFSGARVSAPDLRAGAALCIAGLATDGITIVDDIIYILRGYERFDEKLRSIGALMEQVSTEKEIQKFTLKVS
>NZ_CP036524.1|WP_040435085.1|3556139_3557357_-|MFS-transporter
MKKGTNRYFILAVAAVVNFVHGNPYIWTVFQPHVRSEYDLSLAASSQPFTLIIGIFAVGNMIGGYLQHKIGARATILGGSFVMCAGFFLAAAAPYNMPWLISAGYGVLGGLGSGCAFSMLVAVPQEWFPDKRGLVTGITVGIVGISGVIMNPFCDWLLSAYGYRAAMMTTAAVYAVLSLGGIFISEPGPKQDGEPGPKPVEYEKAQEAEAPGKRQYTTREMFCTKTYYLVSVSMALAVPAYVLVNPLMKSLGMERGLTDSAALAGVMAASAANIAGRFAAPWVSDFLGRKTVIQVLYVIAMISVVGLTAAKGGLFILLISLVSLTYGGFVSVFPVLTSDCFGMRYQGMNFGAVMLGYGIVSILCPYLLAAVQSTPLGTNLSFIAAGGVCVIGMAVTARIKIQQKC
>NZ_CP036524.1|WP_006443312.1|3554646_3555834_-|methionine-adenosyltransferase
MEKRLFTSESVTEGHPDKMCDQISDAILDALMEQDPMSRVACETSTTTGLVLVMGEITTNAYVDIQKIVRDTVREVGYTRGKYGFDCETCGVITAIDEQSPDIALGVDKALEAKENRMSDAEIEAIGAGDQGMMFGYATDETPELMPYPIALAHRLARKLTEVRKDGTLSYLRPDGKTQVTVEYDDKGAPVRLDAVVLSTQHDPDVTQEQIHEDIKKYVFDAVIPSGMADEETKFFINPTGRFVIGGPHGDSGLTGRKIIVDTYGGMARHGGGAFSGKDCTKVDRSAAYAARYAAKNIVAAGLAQRCEIQLSYAIGVAHPTSVMVDTFGTGKLEDDRLVEIIRENFDLRPAGIIKMLDLRRPIYRQTAAYGHFGRTDIELPWEKTDKAAELSRYL
>NZ_CP036524.1|WP_040435084.1|3553071_3554568_-|HAMP-domain-containing-histidine-kinase
MKLKTRLIIAFLTVILIPVLLTYLMVCGLSRYQINSIEKTYEITGTTVKSFANSMQVLSRLTEKPYHELYEMAKEDSEQLEDATCLEKFNKKLEKKKAYLLVRKGTTIIYMGTDIDNVNHVIPQLPSYGESGNTSENGVYLGGEAQALVKQVDFLYGDGEQGSAFIVTDVSNMIPEVQEFIVDLVMGILMVLVLTALLLIFWIYRAVMQPLGKMQCAAQNIKEGNLDFELRPAADDELGRLCRDLEEMRKRLKDNAEEKVKYDKESKELISNISHDLKTPVTAIKGYAEGIMDGVADTPEKMDKYIRTIYNKANEMDLLINELTLYSKIDTNRIPYNFNTLSVNEYFNDCAEDLSLEMESKNVEFGYFNYVASGVQVIADAEQIKRVIHNIVNNSLKYMDKSKGKINLRVKDVGDFIQVEVEDNGKGIAAKDLPNIFDRFYRTDASRNSSKGGSGIGLSIVKKIIEEHGGKIWATSREETGTTMYFVLRKYQEVPIHE
>NZ_CP036524.1|WP_006443310.1|3552389_3553079_-|response-regulator-transcription-factor
MSKILIVEDEEAIADLEKDYLELSGFHVEVANDGELGLKKALEEDYDLFILDLMLPGVDGFDICRQVRNVKNTPIIMVSAKKDDIDKIRGLGLGADDYMTKPFSPSELVARVKAHLARYDRLTGSAAEVNNIIEIRGLKIDTTARRVWVNGEERTFTTKEFDLLTFLASHPNHVYTKEELFREIWDMESIGDIATVTVHIKKIREKVEMDTSNPQYIETIWGVGYRFKV
>NZ_CP036524.1|WP_006443309.1|3550782_3552162_-|potassium-transporter-KtrB
MGERRKNIRWNTMQLLTLGFLGVILLGGILLWLPICNEKPIAFADALFTSTTAVCVTGLVTITPAVQFTLLGKIILLILIQIGGLGVIACATAFFLILRKKITVRERVVIQETYNMDRIGGMVGMVRRAILGTLLVEAAGAVLYAVQFVPEFGVAKGIWYSVFHAVSAFCNAGIDILGSSSLMDYVTNPLINITTMLLIILSGIGFTVWTDVISNSRKIYKNEVPKKWWFTRLALHSKIAIVTTLILLVLGTVAVFGLEYHNPDTIGNMTVGEKVMASMFQSVTTRTAGFATISQGGLHTESKLVCSMLMFIGGSPGGTAGGVKTTTVAMLVLACFTFVRGGRDTECFGRRIDNANIRTGFFVVLVAFTAFLAGVTAITVIEPERVPFIGILYEASSAIGTVGLTADLTPHLSRASQAVIMVMMYLGRLGPITLALLFGGKVHPRDKIRRLPERRIIVG
>NZ_CP036524.1|WP_006443308.1|3550082_3550733_-|TrkA-family-potassium-uptake-protein
MTKQYAVFGLGSFGSSVAVTLQNLGCEVVVVDNRMERIQEIADDVSYAIQADMQDQEVIRSLGARNLDGVIIAVSEDMEASVMATIISKELGVPYVLAKARNEMHAKILRKLGADAVVFPERETGERIAKNLVSTNFADWIALSPEYSITEVAVPDGWTGKSLQELDVRRSHDVSVVGVVSGDKVEVNPDPNKPLEQGMVLILVGANEALESFQKG
>NZ_CP036524.1|WP_006443320.1|3561194_3562568_-|V-type-ATP-synthase-subunit-B
MPKEYRTIQEVAGPLMLVRGVENVAYDELGEIELASGEKRRCKVLEINGNDALVQLFESATGINLSNSKVRFLGRSMELGVSGDMLGRVFDGLGRPIDDGPEILPEERRDINGLPMNPAARSYPEEFIQTGVSAIDGLNTLVRGQKLPIFSASGLPHANLAAQIARQAKVRGTDENFAVVFAAMGITFEESNFFVESFKETGAIDRTVLFVNLANDPAIERISTPRMALTAAEYLAFEKDMHVLVILTDITNYADALREVSAARKEVPGRRGYPGYMYTDLASLYERAGRQNGKKGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRDLYRKGIQPPIDVLPSLSRLKDKGIGEGKTRGDHSNTLNQLFAAYARGKDAKELMTILGEAALTDIDLLYAKFADAFEKEYVSQGYGTDRSIEETLEIGWKLLSMLPRAELKRIDDKFLDQYYGKQ
>NZ_CP036524.1|WP_006443321.1|3562571_3564338_-|V-type-ATP-synthase-subunit-A
MSTGTIKKVAGPLVIAEGMRDANMFDVVRVSNQRLIGEIIEMHGDEASIQVYEETSGLGPGEPVESMEVPMSVELGPGLIASIYDGIQRPLDDIMKVSGNSLQRGVEVASLKRDKKWEFVPVAKAGDEVEAGDVLGTVQETIVVQQKIMVPYGIKGTVKEIRQGEFTVEETVAVIATEDGDKELTMLQRWPVRKGRPYVKKLPPEKPLVTGQRVVDTFFPIAKGGVAAVPGPFGSGKTVIQHQLAKWAEADIVVYIGCGERGNEMTDVLNEFPELKDPKTGQSLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRWAEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGHVISLGQDKREGALSVIGAVSPPGGDISEPVSQATLRIVKVFWGLDSALAYKRHFPAINWLTSYSLYVDNMADWFNNEVAADWMEDRQKMMSLLQEEAELDEIVKMVGMDALSPTDRLKMEAARSIREDFLHQNSFHDIDTYTSLRKQYLMMKLVLAFYEEASEALSQGASMQILINMGVRERIGRYKYTLDADIETEYEKIVNELHTEIAGAFGKEDF
>NZ_CP036524.1|WP_006443322.1|3564365_3564686_-|V-type-ATP-synthase-subunit-F
MYKIAVLGDYDSIYGFATLGLDTFPVSTREEAGEKLHQLTLGDYGIIYVTEALAAELKHEIEKYQEQAVPAVIQIPGISGNTGAGVEGVKKSVEQAVGSDIIFGNE
>NZ_CP036524.1|WP_006443323.1|3564678_3565647_-|V-type-ATPase-subunit
MSEQYTYAVARIRALEVSLFSNSTVDQLIACADYGQCIQFLQEKGWGDSDTPADAEAILNREEEKIWEVVKELSVDMDKFDVLSYPKLFHNLKAAIKEVCTEEENRHIFYEDVAIPGKVMLEIVREKDFGKLPRNMQAAAEEAYETLLHTRDGQLCDVIIDRAALEAVYEAGQQAEDDIIRDYAESTVGVADIKIAVRSQKTAKSLEFMKRAMAECASINVDQLAKAALSGMDAIREYLSGTAYAEGAEALADSPSAFERWCDNRIIQTISPQKYNAFTIGPVIAYVIARQNEIKTVRIILSGKLNDLPDDSIRERVREMYV
>NZ_CP036524.1|WP_006443324.1|3565680_3566274_-|hypothetical-protein
MTGLDKMKSQILDEAKAAADSKLSEAKSQAEDILDKAKAEAAKTTSSISQKSEAEVANYKDRIVSAIDLQRRTKILAAKQEIIAEVLDKAYGTLKTMESGAYFDMLLKLLGKYALPQEGEIYFSSADLERLPDGFEQKINGIAAEKGGRLTLSKTGRNIENGFILAYGGIEENCTLKAMFDAKKDELSDQVHKLLFL
>NZ_CP036524.1|WP_006443325.1|3566315_3566801_-|V-type-ATP-synthase-subunit-K
MSIWNDLGIVYALLGAAVAVFLAGAGSAIGVGIAGQAASGVVTEDPSKFAKVLIMQLLPGTQGIYGLLVGFITLSKIGLLGGGAADISVTTGLLVLAACLPIGIVGLISGKYQGKTSAAAIGIIAKKPDQFGKAMLFPAMVETYAILALLISILSVTAISV
>NZ_CP036524.1|WP_006443326.1|3566800_3568819_-|V-type-ATP-synthase-subunit-I
MAVLQMQRISICALKKDRKAILEKVQSMGVMEINHVVEDDEAFGRMDTLNARQSFDKKAQLADQALAVLDNYAPEKSSMLSSLEGKKLVEQEKFSKAAADKEKIIAAANRLVGCSKEIAENKANILKLENQIESLTPWLTLDVPMDHQGTENVAVLVGMMPGGLTLDGVYARIAEQNPDLEAVDVHIIASDKDAVYLTVLCLKAEEALVEEALRTAGFARPSQVTDKVPARLKTELEAEILKLNKRIEKKEAEIVGFADSREQLKLISDYFRIRSEKYEVLGTLPQSQRTFVMSGYATAEAVPAVQKTIGEKFDCVIDVEDLKEDEEAPTVLKNNSFSSSMEGIVASYGLPHKGEFDPTTIMSFFYVFFFGLMLSDAAYGAIMAIVCFVLLKKYPRMSEGMHKSIKMFMFCGFSTLFWGVLFGGYFGDVIPVFSEKFFGTAVNIKELWFVPLNDPMRLLIYSMLFGMIHLFIGLGIKGYMYLKDGKVLDFFCDVILWYVFLIGLILMLLPSDIFASIAQAEINFPPALNTLAKALAIIGAAGLLFMSGRANKNPALRIALGAYDLYNITGWLSDVLSYSRLLALGLATGVIASVINQMASMIGSGIIGVIAFIIVFIIGHTLNMAINLLGAYVHTNRLQFVEFFSKFYEGGGKPFEPFHSDTKYVDIKEETL
>NZ_CP036524.1|WP_006443327.1|3568857_3569166_-|hypothetical-protein
MVEETIKAIKETEREAEEIVKNADTECTSILEKASADAGRIKEEAEAEAKAKAKASLQAAKEAGETEAEKALAEVETEIASLKEAARQKEGDAISAVIAELV
>NZ_CP036524.1|WP_006443329.1|3569327_3569819_-|tRNA-(cytidine(34)-2'-O)-methyltransferase
MLNIVLHEPEIPANTGNIGRTCVAANARLHLIEPLGFRLNEKNLRRAGMDYWDELDVTTYIDFDEFLEKNEGARIYMATTKAPNVYTDVRYEPDCYIMFGKESAGIPEEILVKHKEDSIRIPMAGDIRSLNLGNSVAIILYEALRQNGFAGMNKEGHLHRLTW
>NZ_CP036524.1|WP_006443331.1|3570005_3570890_-|hypothetical-protein
MMSTKLQGERAVSATAFACGQSKEIGVHALAESLNELAAAGAGAVEARVHIMIPDGYGRPRLAAVQKLIEKACGARGVTLIFLEQYKTPAAALPLVSVTCTGTAEYTDRVIRPGQDIVLTKWAGLGGMVRILQEKEDELEERFAPAFIKQIKEYAGEIFAGEELPAARQMGVSVFCQVTEGGIFAALWNLAREAETGLSVDMKKIPVRQETIEVCENYRLNPYQLMSAGSFLMVADNGRELARELTGRGMKAAVIGRMTDNNDKVIQNGEEIRFIDRPAPDELNKILGHTKRGE

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP036524_6	6.1|3169643|22|NZ_CP036524|CRISPRCasFinder	3169643-3169664	22	NC_017974	Cronobacter phage CR3, complete genome	8627-8648	2	0.909
NZ_CP036524_6	6.1|3169643|22|NZ_CP036524|CRISPRCasFinder	3169643-3169664	22	MN855617	Myoviridae sp. isolate 527, complete genome	7178-7199	2	0.909
NZ_CP036524_6	6.5|3169832|31|NZ_CP036524|CRISPRCasFinder	3169832-3169862	31	MH825709	Mycobacterium phage NicoleTera, complete genome	4852-4882	6	0.806
NZ_CP036524_1	1.4|228417|34|NZ_CP036524|CRT	228417-228450	34	MF417928	Uncultured Caudovirales phage clone 10S_8, partial genome	1439-1472	8	0.765
NZ_CP036524_2	2.2|2483902|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder	2483902-2483935	34	NZ_CP019601	Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence	8373-8406	9	0.735
NZ_CP036524_3	3.8|2659120|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR	2659120-2659152	33	NC_010374	Methylobacterium sp. 4-46 plasmid pM44602, complete sequence	5724-5756	9	0.727
NZ_CP036524_1	1.1|228221|32|NZ_CP036524|PILER-CR,CRT	228221-228252	32	NZ_CP027438	Escherichia coli strain 2012C-4221 plasmid unnamed1, complete sequence	74202-74233	10	0.688
NZ_CP036524_2	2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder	2484504-2484537	34	NZ_CP023739	Methylosinus trichosporium OB3b plasmid pOB3b2, complete sequence	69824-69857	10	0.706
NZ_CP036524_2	2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder	2484504-2484537	34	MK496050	Pseudomonas sp. strain FFUP_PS_41 plasmid pJBCL41, complete sequence	171753-171786	11	0.676
NZ_CP036524_2	2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder	2484504-2484537	34	MN961670	Pseudomonas putida strain 420352 plasmid p420352-IMP, complete sequence	454796-454829	11	0.676
NZ_CP036524_2	2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder	2484504-2484537	34	MN693835	Marine virus AFVG_250M729, complete genome	14536-14569	11	0.676
NZ_CP036524_2	2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder	2484504-2484537	34	MN694058	Marine virus AFVG_250M728, complete genome	14537-14570	11	0.676

1. spacer 6.1|3169643|22|NZ_CP036524|CRISPRCasFinder matches to NC_017974 (Cronobacter phage CR3, complete genome) position: , mismatch: 2, identity: 0.909

ggcatctcctttgtcgcctttc	CRISPR spacer
tgcatctcccttgtcgcctttc	Protospacer
 ********.************

2. spacer 6.1|3169643|22|NZ_CP036524|CRISPRCasFinder matches to MN855617 (Myoviridae sp. isolate 527, complete genome) position: , mismatch: 2, identity: 0.909

ggcatctcctttgtcgcctttc	CRISPR spacer
ggtatctcctttgtcgccttta	Protospacer
**.****************** 

3. spacer 6.5|3169832|31|NZ_CP036524|CRISPRCasFinder matches to MH825709 (Mycobacterium phage NicoleTera, complete genome) position: , mismatch: 6, identity: 0.806

ctgaggacctgtgactccggtcagtccctga	CRISPR spacer
tcgcggacctgtggctccggtcagaccctgt	Protospacer
..* *********.********** ***** 

4. spacer 1.4|228417|34|NZ_CP036524|CRT matches to MF417928 (Uncultured Caudovirales phage clone 10S_8, partial genome) position: , mismatch: 8, identity: 0.765

gtgtttttgaatatggaggagatcaccactcttt	CRISPR spacer
gttaatgtcaatatggaggagattacaactcttc	Protospacer
**   * * **************.** ******.

5. spacer 2.2|2483902|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP019601 (Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence) position: , mismatch: 9, identity: 0.735

cagttttt----ccttttaaacctgtaaaatatttaac	CRISPR spacer
----tttcaacaccttttaaaccagttaaatatttatt	Protospacer
    ***.    *********** ** ********* .

6. spacer 3.8|2659120|33|NZ_CP036524|CRISPRCasFinder,CRT,PILER-CR matches to NC_010374 (Methylobacterium sp. 4-46 plasmid pM44602, complete sequence) position: , mismatch: 9, identity: 0.727

accagtgaagagagggtgaggctggcttattat	CRISPR spacer
tgaagtgaaaagagggtgtggctggctctgcat	Protospacer
   ******.******** ********.  .**

7. spacer 1.1|228221|32|NZ_CP036524|PILER-CR,CRT matches to NZ_CP027438 (Escherichia coli strain 2012C-4221 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gacatagggtacgtccatagtgataaatatta	CRISPR spacer
atcataggatacatccatagtgatagtttggt	Protospacer
. ******.***.************. *    

8. spacer 2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP023739 (Methylosinus trichosporium OB3b plasmid pOB3b2, complete sequence) position: , mismatch: 10, identity: 0.706

tttcgggcaattggaagaaggcctggggtggtat	CRISPR spacer
cctcgggcaattgggagaaggcctcggcaagctg	Protospacer
..************.********* **  .*.  

9. spacer 2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder matches to MK496050 (Pseudomonas sp. strain FFUP_PS_41 plasmid pJBCL41, complete sequence) position: , mismatch: 11, identity: 0.676

tttcgggcaattggaagaaggcctggggtggtat	CRISPR spacer
gatcgggcaatttgaagatggcctggcccagctc	Protospacer
  ********** ***** *******  ..*. .

10. spacer 2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder matches to MN961670 (Pseudomonas putida strain 420352 plasmid p420352-IMP, complete sequence) position: , mismatch: 11, identity: 0.676

tttcgggcaattggaagaaggcctggggtggtat	CRISPR spacer
gatcgggcaatttgaagatggcctggcccagctc	Protospacer
  ********** ***** *******  ..*. .

11. spacer 2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder matches to MN693835 (Marine virus AFVG_250M729, complete genome) position: , mismatch: 11, identity: 0.676

tttcgggcaattggaagaaggcctggggtggtat	CRISPR spacer
aaagaggcaattggaagaacacctggggttaact	Protospacer
    .************** .******** .  *

12. spacer 2.11|2484504|34|NZ_CP036524|CRT,PILER-CR,CRISPRCasFinder matches to MN694058 (Marine virus AFVG_250M728, complete genome) position: , mismatch: 11, identity: 0.676

tttcgggcaattggaagaaggcctggggtggtat	CRISPR spacer
aaagaggcaattggaagaacacctggggttaact	Protospacer
    .************** .******** .  *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2294012 : 2304352	9	Orpheovirus(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP036524|2294012:2304352|DBSCAN-SWA
CTTAGCCTGTTGTTCTCTCTATATCCATAACGCCTTCCACCTGGCGCAGCTTCTTTACTATCGTGTCCAGTTCTTCCCTTCCGTGCACGATAAAGCCGGTCTCGATCGTCGCCGTTCCCTGCTTGCTCGTGCGCACGTTCATGGACTTCACATCCACCGTCGCCTCGGTAAATATCTTGGACATCTCCATGAGAAGCCCCTGCCTGTCATGCGCAAACATCTTGATCTCCGCCAGGTACTGTCCGCCGTTCTGCTCCGCCACTTCGCTTTCCCACTCCGCGTCGATGAGCCGGACACGCTCGCCCTCGGTCAGATGTATCATATTCACACAGTCTGTCCTGTGGATGGACAATCCCCGCCCGCGGGTCACAAACCCGACGATCTCATCTCCCGGAACCGGGTTGCAGCATCTGGAGAAACGGACCGCCATATCGTCGATCCCTTTGACGACGATACCGCTCTTTGATTTGGCGATATGCACTTTGTTCTTGGACGCTTCCGCCACACGTTCCAGTACGACTTCGTCGGTCATCTCCTGCTTGTGTTCCTTGCCGTACTCTTCCACAAGGCGGTTCACGACCTGTCCTTCCTTCAGTCCTCCGTGTCCGATGGCCGCCAGCACAGACTCCCAGTCTTTAAAACCGTATTTCTTCTGCACGATCTCCATGTACCTGTTGATCATGATATCGCTCTGGGTGATCGCCTTTGCTTTACAGTAGGCGGCGATCATCTCCTTGCCCTTTACGATATTGCTCTCCTTGAATTCCTTCTTGAACCACTGGTTGATCTTGTTTTTCGCCTGTGTGCTCTTTACAATGCCCAGCCAGTCCCGGCTCGGGCCCTTGGAATTCTGGGAAGTCAGGATCTCTATCCTGTCCCCGTTCTGTATCTTATAGTCTATATTGACCAGCTTTCCGTTGACGCGGGCTCCTACCATCTTATTGCCGACCGCACTGTGGATGGCATATGCAAAATCGATCGGCGTGGAGCCGTTCGGAAGATTCTTGACGTCCCCCTGTGGGGTAAAGCAGTACACATCCTCGGCAAACAAGTCCAGATCGCCTTTGAGCAGATTTAAGAATTCCCTGTTGTCGGACATGTCTCTCTGCCATTCGAGGATCTGCCGAAGCCAACTCAGCTTCTCCTCTTCCTGCGCCTGTACGCTCTTCTTGCCGTCATTGGATTCTTTGTATTTCCAGTGGGCGGCAATACCATATTCCGCCGTCTTGTGCATTTCCTCCGTACGGATCTGTATTTCAAACGGCTGCCCGACCGAACTCATAAGCGTCGTGTGAAGCGACTGGTACATATTCGGCTTCGGCATTGCAATATAGTCTTTAAAACGCCCCGGTATCGGCGTATACATCTCGTGGATCACACCGAGCGCGGCGTAACAGTCCTTTACAGAATCTACGATGATCCGCACGGCGAACAGGTCATATATCTGGTCCACCGTCTTCTCCTGGTTCACCATCTTCTTATATATGCTGAAGAAATGCTTCACCCGGCCGTTGACGTCTGCCTTTATGTTGGCGTTCTTCATATGTGTGGACACTTCATCTACGATCTGCTGTACAAACTCCTCGCGCTCCGTCTTCCTCGAATTGATCTGATTCACAAGATCAAAAAACACTTCCGGCTGTGAATACTTGAGCGCCAGATCGTCAAGTTCTGTCTTGATCTTGGATATACCGAGTCTCTGGGCGATCGGAGCATAGATATCCATCGTCTCCTTTGCCTTTTCCTTCTGCTTGGCCGGCGTCATAAACTGTAGCGTCCGCATGTTGTGCAGCCGGTCCGCAAGCTTGATGATAATGACCCGGATATCCTTTGCCATGGCAAGAAACATCTTTCTTAGATTTTCCGCCTGTACTTCCAGTTTATCCGAAGAATAAGAAAGCCGGCCGAGCTTTGTGACCCCGTCCACCAGAAGCGCAACTTCTTCCCCGAAATTCTTTTTTATCTCTTCTTCCGATACAGATGTATCCTCCACGACATCGTGGAGCATTCCTGCCGCGATCGTCTCCTTATCCATCTCCAGATTGGCCAGGATGATGGCGACCCAGAGCGGATGGACAATGTACGGCTCTCCGGACTTGCGGCACTGGTCCCCGTGCGCTTTCCTGGCTGTCTCATACGCCTTCTCTATCATGGATACATCCGTTGAAGGATGGTACTTCCGGATACGGGCAATTAACATGTCATAAAGCTGGTCCGGATCTTCATAATCTCCGGGAGCCTTCACGGCGTGCCCGTCCACAATTTCCAGTCCCTTTGAGATCTCATCCGCAATGGATTCCGGTGCTATGCGGTTTTCTGACTCATATATCATTTTCTCTGACATATTAATGCCTCCTTCCTTTTCAAATTTTAATTCTGTCATTTGCCTGGATAAGCTATCACGGATTCCACATCATATCCCTTCAGCCGCTTTCTTCCTTCCAGACCGGATAATTCCATAAGGAATACTGCCTTCACCACTTTGCCGCCCAGCCCTTCAACGAGCTTAATCATAGCCTCATTCGTCCCGCCTGTGGCGATCAGGTCATCGATGATGACGACCTTCTGCCCTTCCTTGACCGCATCTCTGTGTATCTCAAGCTCCGCGGTCCCGTACTCCAGCTCATATTGGATAGAGACTGTCTCACATGGCAGCTTTCCTTTCTTTCTGATCGGAATAAACGGTTTATGCAGATTATATGCAATAGGGACACCAAAGATAAACCCTCTCGACTCCGGACCCACGACCACGTCAAATTCCACACCGTCAAGCTTTTCCTGCATCAGGTCAACGGCAAGATGCAGGCCGTCCGCATCCTGGAGCACGCTCGTGACATCCCTGAAAATGATACCCTGCTCCGGGAAGTCCGGAATACTCCTTACATACTCTTCTATTGGTTTCATGACACCCTCTCCATTCTCTCATATAAATACAAAAATAGTATAACATTAGTTTATGTAATTTTCAAACAATTCTATACATCTCCGACAGTTTACTGGTAATGCGTGATAACGATCTGCATTGTCCGGCTCCCCATATACTCATTTACTTCCGGATAATACGTCACAGACAGTGTCATTTTGCTTCTTCGCCGGCCCAGGAACTGTTTCAGCGCCTCTTTGCCGTATTGTTCCTCCAGATAGGAGCAGAACCGGCCGGTATCACCGAAATAAACAGCCTCAGTCTCATTTCCCGCCGCATCCTTCACGCGCATCTTCAGCACATTTCTATTCTTTCCAAATATCTGTCCGCCGAGCAGTTCCACCTTTCTCGCGGCAAATACCGGCTTTTTATTTCCATTTCCGAAAGGCTCCAGATACTTGAGCTCTCTGACGATATCCTCTGTGACACAGGAGAACGGCATCTCCATATCGATCACTACTTTTTCCCGCATGTCGCTTTCCTTGAGCGTACAGTTTTCATTCAGCCGCCTGCGAAACTGCTCCACATTCTCTTTCTCCAGCGAAAACCCGGCCGCCATCATATGACCGCCGTACTTTGTCAAAAGCTCCCTGCAGCCTGCCAGTTCTTCGTACATGTGATAAGCTTCGATGGAACGCCCGGAACCTTTCACCCCGTCTTCCGCGTCTGTCATGACGTATGCCGGGCGGCAGTAGCGCTCCCGCAGCCTTCCCGCCACGATGCCCGCCAGGCTTTCATGACAGTCCGGCAGGTATACCGCCAGAACCCGGTCCTTTCCGAGAGACGTCGTCTCGATCATCTGTACTGCCTGCTCTACCGCGGCGGCTGTCATCTCTTTCCGGCTGTCATTCAATGCCTTTAAGTCTCCCGCCAGTATGTCCGCCTCTTTTTTACGTTCCGCACAGAGCAGGTCAAGCGCGCGCTTCGCTGTATCCAGTCTTCCGCCCGCATTCAAACACGGTCCGAGGACGAAACCGATATGGTAAGAGTTCAGCTTTTCCCGGTCTATGCCGGTACACTCAATGAGAGCGCCAAGTCCCGGATTTACCGTTCTTCTCAGACGTTCCAGCCCTTCCCTGACAAGGATCCGGTTCTCATCTACCAGCTCCATCACATCTCCCACTGTGGCGACCGCCACATTTTCCAAAAGGTCGTCCAGATCATCCGCCTCATTTCCCATAGCCTCGTACAACGCCTCTATGAGCTTGTAGGCAACTGCCGCCCCGCACAGTCCCTTGAACGGGTAGCCGCAGCCCGGCTGCTTCGGGTCAATGACCGCGTCGGCGGCGGGAAGTATATAATTCTTTTCCTCCCCCTCCGACTCATATGGCACCTCATGGTGGTCTGTCACAATGACCGTCATGCCGAGCCGTTTGCCGTAGGCGATCTCCTCACTGGCCGCGATTCCGTTATCACAGGTCACGATCGTGTCTATGCCGTCCCTGTATGCCCGTTCGATCAGTTCAATGTTCAGCCCGTAGCCGTCCTTTATCCGGTCCGGTATGTCACTGTCCGCACAAGCCCCTGATTTTCTCAGACCTTTCAGCAGAATATAAGTGGCGTTCACTCCGTCTATGTCGTAGTCTCCAATAATACGGATCTTCCTGTTTTCTTCTATCTTCTCCCGGAGGATCTCCACCGCCTTGTCCATATCCTTCATGAGCATTCCGTCATACAGGTCGGTGATCGTTCCGTTCAGATAACGGTCCACCGCCTCCGGCCCGATCACATCCCGGTTTCTGATCAGGCAGGCCAGCCTTGGACTGATGCCGAACTTTCTCCCCAGTTCCTCGAAATCAGCTCCCTTTCTGAGCAGTATCCACTGTTCCATATCTTTTCCTCCACCAAAACAGCCACAGCCATATAAATATGGCCATGGCTGATATACTGTGTTTCTTTTGTCTATCTCTTTTTCTTTGTTTCCGCCGCTTTCTTTCCGATCTTTGTCCTCATGACATACCAGAGCGCGCCGGTGATGCAGACAGAGGAATACGCGCCGCAGATAATACCTACCATGAGCGGAAGTGCGAACTCCCGGATAGAGCTTACGCCCATCACGAACAGTATGGCCACCATGACAAATGTCGTCAGAGAAGTGTAGATACTTCTCGTCAGTGTCTGTGTGATACTCTTGTTCACCACGTCCACAAGCTCCGTCGTCTTGGATCTCAGGCGCAGTTCCTCCCGGATACGGTCAAAGATGACGATCGTGGCATTGATCGAGTAACCTACGATCGTGAGCATACACGCGATAAATGTATTGCCCACAGAGATTCTGGCAACCGCATAGAAGGTCAGCACGACGAGCACATCGTGCAGCAGCGCGGTAACCGCACTTGCGGCAAAGCGGATATCCTTGAACCTGAACCAGATGTATATGAGCATGAAGATCGTAGCGACGATCACTGCCATGATCGCATCCTGCCTCATCTCGTTACTGATCGTGGAACTGATATTCTCCGCGGTAATGAGCGACTCATCTACTTTAAATTTGTCGGCAAGCGCTTTGTTCAGCGCCTCGCGCACATCCAGTCCAAGCGTTTTCGTCTTAATGATGACCTGATTAGTATCTGCAACCTTCTGTGTCTGGACATTGGCGTCTCCGGTCACTTCCTCGACAACAGGCACGATCTCTTTGTCTATCTCTTCGATCGTATAGTCTTTGTTAAACGTCACATTCGTGGAAGTACCACCCTCAAATTCCAGACTGTAGGCAAACGCTCCCTTTCCTTTTGAGCCGTTCACGCCCATGAATACGAATCCAAGTATGACGACCGCAAGCGACAGGGCAAAAAACCATTTCTTCCTGCCGAGGAAGTCAATGGGCTTTCTCTCTTTTCTCGGACGGTAATACAGCTTCTCTTTCCTGAGTCCTACCGCATAGAACGCATACACGATCATCCGTGTGATCACAAGCGCGGTAAACATGGACACGATAATACCGATCGCCAGCGTCTGCGCAAAGCCCTTTACCGAACCGGAACCTTTGAACCAGAGTACCGCCGCGGCAATGAGTGTTGTCACATTGCCGTCCACGATAGCGGACATGGCTTTCTGAAAGCCCGTCTTAAGAGAATTGCGGACGCTCTTCCCCTTTGACATCTCTTCCCGCACGCGGGCAAATATAATAACATTGGCATCGACCGCCATACCGATACTCAGGATAATACCCGCAATACCCGGCAGCGTCAGCGTTACGTTGAATGCATTTAAGATCACAAGCACCAGCCCGGTGTAGATGATCAGCGCAAGACTGGATGCGAGACCCGGCAGAAGATACACGCATATCATAAAGAGAAATACGATAGCCAGACCAATGGCCCCCGCCTTTAAGCTTGTGCTGATCGCCTGTTCTCCAAGCTGCGCGCCGACCACGTTGGAACGCAGTTCCTCCAGTTCCAGCTTCAGTCCGCCGATACGGATGGTGGAGGCAAGGCTCTCCGCCTCTTCATAGCTGAAGTTGCCTGTAATATAGGCCTGTCCGCCGGTGATGGCTGTCTGTACGGTAGGACTGCTGATCGTCTCCCCGTCATAGATGATGGAGATCGGCTTTCCTACATTTGCTTCCGTCGCCTCCGCGAATTTCTTCGTTCCCTCTTCGTTCAGGTCAAGCTCTACGCTGTATTCCTTATTGCCCATATCGTCTTCACCGGCACGGGCCGAAGCAGTCTTTACATCAGAACCTGTGATCACCGTCTCATTGTCCTGTGTCTGGAATACGAGAGAACCCGGCTTTCCAAGTTCATCCAGGATCGCGTTGGCATCGCTTACACCCGGGATCTCGATATTGATCCTGTCATCGCCCTCCTGATATACGTTCGCTTCTGTGCTGTACTGCTCCACACGCTTCTGAAGCTTGTAGATCGTATCCCGCATCTCTTCTTCCGACGGGTTCTTGTCTTTTACCTGGTAAGTGATGCTCACACCGCCCGCCAGGTCAAGGCCGAGCTTAATGTTTTCCGCAGAACCGGTCTTGCCTTTACCGAATCCTGCCACCGTTGTGAATGCGAGCAGTGCTATGAGAGCCGCCGCCACAACAAGACTAAGTATGCCTTTACTCTTCTTCATGGTCTACTTCCTTTCTCTTATCCTTCCAAGTCTTCCTCTGCCAGCGCCGCCTTCATCATGATCGCGCACTCAACACGCTTGCGCTGCATCTCACAGCCGATCTCATACGCTTCATGGATCGTTCCGTGAAAATTATAAGCATTCGCCATACAGCCGCCGCTGCAGTAAAATTTTGCAAAACAATTCTTACACTTTTCTTTGGAATATACGTTGCAGCTTCTGAATTCATCTGCAATCTCCGGTCTGACGATCCCTTCCTCTACATTCCCCATAAGAAATTCTTCCTGCCCCACAAACTGGTGGCACGGATAAAAATCTCCCCACGGGGTCACCGCCAGATATTCCGTACCGGAACCGCACCCTGACAAACGCTTTGCCACGCACGGTCCACCGTCTAAGTCTATCATAAAATGGAAGAAATTAAAACCTTTTCCTTCCTTTTCCCGGCCGATCATGATCTGCGCGAGCCTGTCGTATTCCTGCATGATCGCCGGAAGGTCCTCCTCCTGGATCGCATACGGGTCTGTCTCCTCCCCCACGACCGGTTCTATGGACATCTGTTTGAATCCCAGATCCGCAAAATGAAGGATATCCTCCGCAAAATCCAGATTATTCCGTGTAAATGTACCTCTTATGTAATACTTTTCCTGATTCCTGCTCTCAGCCAGTTTCTGAAACTTCGGCACAATAAGTTCGTAACTGCCTTTTCCGTTTCTGAACGGCCGCATCCGGTCGTTGATCTCTTTCCGTCCGTCGAGGCTTAAAACGACATTGTCCATTTCTCTGTTCACAAATTCCTGTATTTCGTCATTTAAAAGTACACCGTTCGTCGTCACGGTGAAACGGAAATGCTTGTCGTGGATCTTCTCCTGGCTCCTGCCGTACGCGACAAGGTCCTTCACGACCTGCCAGTTCATGAGCGGTTCCCCTCCGAAAAAATCCACTTCCAGATTATGTCTGCTGCCCGAATTGGCGATGAGAAAATCCAGCGCCTTTTTCCCGACCTCATAGCTCATGAGCGCGCGTCTTCCGTGATACTCTCCTTCTTCCGCAAAGCAGTACCTGCAGGCCAGGTTGCAGTCGTGTGCGATGTGCAGGCAGAGCGCTTTTACGACTGTCTTTCTCTTCTTCACTTCCTCGATCAGGCCTTCATGCGTGTCGGACGTAAACAGCCTGCCTGCTTCTGTCAGTTCCGCGGCATCCGCAAGCGCCTCCCCGATATCTGAACTATCATAAGCTCCGCCGAGGTGTTCCCTCAGCCGCTCAGGCAGCTCCGGTGCCCGGAGGCTTTCCGCCGTCCATGTATCACGTTCCCGCCCAAGCTGCTCTATCACATCATAACACAGTTCATCTACTACGTGGACCGCACCGCTGTTCACATCCAGAACTATATTATATCCATTGTTTTTATACTGGTGAATCAAACTGTATATCCCCCTTTTTCAAACAACAAGAAACAGCGACCCTTAAGACCGCTGTCCCGAGTATTCTGTATGATGTTTCATTATTTCTTCTGTTCGCAGGTCTGGTTTCCTACTGTACAGGAAGTCTTACATGCTGACTGGCAGGATGTCTGGCATTCTCCGCATCCGCCCTTTTTAACTGTATGATTCAAAGTCTGTGTATTTAATGTCTTCACATGTTTCATGTCAATATCCTCCTTACGTTTGCTTAACTTTTGTTATTATAACATAAGCAATATGTTTTTGGAAGTATTTTTCTCGCTGTTTTTCATGAAATCATTCCGCCCACCATACCTCCGCCGGCGCATAAAATAAACGTCGTTATGAGGTTCGCGCCGTTTCCGTTCAGCGTATGGTATACCCCGAGCGTAATCAGAAGCAGAAGTGCAAAATATCCGATCCCCAGGCCCAGTCCCCACACAAACCTGCGCACCCTGGCAAGCTTACCGATAATGATGCCCCCGACTAGAGTGGCCATGACATAGATAGCCACGATACCTGCCGATACCGCTTTTTCATTCAAATCCATCTTATAAAGCAGCACCGTCAGCACAAGCAGCATGATTCCGGTAATAATATAAGAAGCAAGCAGTGACTTTAACACCCACATGACTTTTGAATCTTTCTGAATCCGTCTCTCCATCTAATCCCTCCTCGTCTATCACAAGGTATGAATCAGATTGCGGATTTATGCCATTATTGTTCCATCTGCCTGCCTAAAAATCCCGCCGCGCAGGCTGCCATCTTCTGTTCCAGTTCTGAAAACTTCTTTTTACTCTCTTTTGTAAGGAAGATCACGCCTCCGATGACGTCGCCCTCACATACGATCGGATGAATGACCTGGTAATGATATTCATCATCCTGGTCATTGATCGTCTTCATGAACTTCTTGTCCCCGGCCGCCGCCAGAATCGGATTTCTCTCCTCCAGCGCCTTCTCCAGCTGCTTGCTGATGTATTTATCCTGAAAATCCTTCTTGCCTCCGCCGGCGGAAGCTACGATCTGGTCCATATCACTGACACATACAAGGCAGCCCATCGTCTGGGCCAGGCTTTCTGCATATTGTCTCGCAAAAGCGGACAGTTCGCCTATCGGAGAATACTTTTTCAGAATGATCTCTCCTTCTCTGTCTGTAAATATCTCCAGCGGATCTCCTTCGCGTATTCTTAATGTCCTCCGTATTTCTTTGGGAATCACCACTCTTCCCAGGTCATCGATCCTTCTCACTATTCCAGTTGCTTTCATGTCCTTTATTCCCTCCATTTATCTTGATTGGCAGATAAATGTATTATCTGTTAAAAGAAGGAAAATCATACATGCGCCGCAACAATAATAAATACGGAACCGCCTCCTGATGTACAAGATACAGTCTTGAAAATACAGTCTCAGTATACTATTATATTTTATAGAATCACAAAAAAATCAAACGGAGGAATCATCATGAGTAAAATCGAAGAAGTAAGAAGCGACATGATAGGGGCCATGAAAGCAGGCGATAAGGAGACAAAGGAAACGCTGTCCATGCTGCTGGCGGCTCTTAAGAATAAAGCCATCGACAAGCGTTCCGACCTGACGGAAGAAGAAGAGACACAGGTCATCTTAAAAGAGATCAAACAGACAAAAGAAACACTGGAGATGACCCCCGCAGACCGGACCGAGATCATAGAAGAATGCACAAAACGCCTGTCCGTACTGGAAAGCTACGCCCCGAAAATGATGGATGAAGCAGAGATCCGCGAGATCACCGCCGCCACACTAAAAGAACTCGGGATAGAAACCCCAGCCGCAAAAGACAAAGGCAGAATCATGAAAACACTCATGCCAAAAGTAAAAGGCAAAGCAGACGGCAAACTAGTCAACGACATTGTCGGAAGCTTTTTCAAATAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP036524|2294012:2304352|2302733_2303108_-|WP_006442054.1|DBSCAN-SWA
MERRIQKDSKVMWVLKSLLASYIITGIMLLVLTVLLYKMDLNEKAVSAGIVAIYVMATLVGGIIIGKLARVRRFVWGLGLGIGYFALLLLITLGVYHTLNGNGANLITTFILCAGGGMVGGMIS
>NZ_CP036524|2294012:2304352|2303905_2304352_+|WP_006442056.1|DBSCAN-SWA
MSKIEEVRSDMIGAMKAGDKETKETLSMLLAALKNKAIDKRSDLTEEEETQVILKEIKQTKETLEMTPADRTEIIEECTKRLSVLESYAPKMMDEAEIREITAATLKELGIETPAAKDKGRIMKTLMPKVKGKADGKLVNDIVGSFFK
>NZ_CP036524|2294012:2304352|2303161_2303710_-|WP_040434715.1|DBSCAN-SWA
MKATGIVRRIDDLGRVVIPKEIRRTLRIREGDPLEIFTDREGEIILKKYSPIGELSAFARQYAESLAQTMGCLVCVSDMDQIVASAGGGKKDFQDKYISKQLEKALEERNPILAAAGDKKFMKTINDQDDEYHYQVIHPIVCEGDVIGGVIFLTKESKKKFSELEQKMAACAAGFLGRQMEQ
>NZ_CP036524|2294012:2304352|2302506_2302650_-|WP_006442053.1|DBSCAN-SWA
MKHVKTLNTQTLNHTVKKGGCGECQTSCQSACKTSCTVGNQTCEQKK
>NZ_CP036524|2294012:2304352|2297004_2298765_-|WP_006442050.1|DBSCAN-SWA
MEQWILLRKGADFEELGRKFGISPRLACLIRNRDVIGPEAVDRYLNGTITDLYDGMLMKDMDKAVEILREKIEENRKIRIIGDYDIDGVNATYILLKGLRKSGACADSDIPDRIKDGYGLNIELIERAYRDGIDTIVTCDNGIAASEEIAYGKRLGMTVIVTDHHEVPYESEGEEKNYILPAADAVIDPKQPGCGYPFKGLCGAAVAYKLIEALYEAMGNEADDLDDLLENVAVATVGDVMELVDENRILVREGLERLRRTVNPGLGALIECTGIDREKLNSYHIGFVLGPCLNAGGRLDTAKRALDLLCAERKKEADILAGDLKALNDSRKEMTAAAVEQAVQMIETTSLGKDRVLAVYLPDCHESLAGIVAGRLRERYCRPAYVMTDAEDGVKGSGRSIEAYHMYEELAGCRELLTKYGGHMMAAGFSLEKENVEQFRRRLNENCTLKESDMREKVVIDMEMPFSCVTEDIVRELKYLEPFGNGNKKPVFAARKVELLGGQIFGKNRNVLKMRVKDAAGNETEAVYFGDTGRFCSYLEEQYGKEALKQFLGRRRSKMTLSVTYYPEVNEYMGSRTMQIVITHYQ
>NZ_CP036524|2294012:2304352|2298836_2301002_-|WP_006442051.1|DBSCAN-SWA
MKKSKGILSLVVAAALIALLAFTTVAGFGKGKTGSAENIKLGLDLAGGVSITYQVKDKNPSEEEMRDTIYKLQKRVEQYSTEANVYQEGDDRINIEIPGVSDANAILDELGKPGSLVFQTQDNETVITGSDVKTASARAGEDDMGNKEYSVELDLNEEGTKKFAEATEANVGKPISIIYDGETISSPTVQTAITGGQAYITGNFSYEEAESLASTIRIGGLKLELEELRSNVVGAQLGEQAISTSLKAGAIGLAIVFLFMICVYLLPGLASSLALIIYTGLVLVILNAFNVTLTLPGIAGIILSIGMAVDANVIIFARVREEMSKGKSVRNSLKTGFQKAMSAIVDGNVTTLIAAAVLWFKGSGSVKGFAQTLAIGIIVSMFTALVITRMIVYAFYAVGLRKEKLYYRPRKERKPIDFLGRKKWFFALSLAVVILGFVFMGVNGSKGKGAFAYSLEFEGGTSTNVTFNKDYTIEEIDKEIVPVVEEVTGDANVQTQKVADTNQVIIKTKTLGLDVREALNKALADKFKVDESLITAENISSTISNEMRQDAIMAVIVATIFMLIYIWFRFKDIRFAASAVTALLHDVLVVLTFYAVARISVGNTFIACMLTIVGYSINATIVIFDRIREELRLRSKTTELVDVVNKSITQTLTRSIYTSLTTFVMVAILFVMGVSSIREFALPLMVGIICGAYSSVCITGALWYVMRTKIGKKAAETKKKR
>NZ_CP036524|2294012:2304352|2296390_2296915_-|WP_006442049.1|DBSCAN-SWA
MKPIEEYVRSIPDFPEQGIIFRDVTSVLQDADGLHLAVDLMQEKLDGVEFDVVVGPESRGFIFGVPIAYNLHKPFIPIRKKGKLPCETVSIQYELEYGTAELEIHRDAVKEGQKVVIIDDLIATGGTNEAMIKLVEGLGGKVVKAVFLMELSGLEGRKRLKGYDVESVIAYPGK
>NZ_CP036524|2294012:2304352|2301019_2302426_-|WP_006442052.1|DBSCAN-SWA
MIHQYKNNGYNIVLDVNSGAVHVVDELCYDVIEQLGRERDTWTAESLRAPELPERLREHLGGAYDSSDIGEALADAAELTEAGRLFTSDTHEGLIEEVKKRKTVVKALCLHIAHDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRHNLEVDFFGGEPLMNWQVVKDLVAYGRSQEKIHDKHFRFTVTTNGVLLNDEIQEFVNREMDNVVLSLDGRKEINDRMRPFRNGKGSYELIVPKFQKLAESRNQEKYYIRGTFTRNNLDFAEDILHFADLGFKQMSIEPVVGEETDPYAIQEEDLPAIMQEYDRLAQIMIGREKEGKGFNFFHFMIDLDGGPCVAKRLSGCGSGTEYLAVTPWGDFYPCHQFVGQEEFLMGNVEEGIVRPEIADEFRSCNVYSKEKCKNCFAKFYCSGGCMANAYNFHGTIHEAYEIGCEMQRKRVECAIMMKAALAEEDLEG
>NZ_CP036524|2294012:2304352|2294012_2296355_-|WP_040434714.1|DBSCAN-SWA
MSEKMIYESENRIAPESIADEISKGLEIVDGHAVKAPGDYEDPDQLYDMLIARIRKYHPSTDVSMIEKAYETARKAHGDQCRKSGEPYIVHPLWVAIILANLEMDKETIAAGMLHDVVEDTSVSEEEIKKNFGEEVALLVDGVTKLGRLSYSSDKLEVQAENLRKMFLAMAKDIRVIIIKLADRLHNMRTLQFMTPAKQKEKAKETMDIYAPIAQRLGISKIKTELDDLALKYSQPEVFFDLVNQINSRKTEREEFVQQIVDEVSTHMKNANIKADVNGRVKHFFSIYKKMVNQEKTVDQIYDLFAVRIIVDSVKDCYAALGVIHEMYTPIPGRFKDYIAMPKPNMYQSLHTTLMSSVGQPFEIQIRTEEMHKTAEYGIAAHWKYKESNDGKKSVQAQEEEKLSWLRQILEWQRDMSDNREFLNLLKGDLDLFAEDVYCFTPQGDVKNLPNGSTPIDFAYAIHSAVGNKMVGARVNGKLVNIDYKIQNGDRIEILTSQNSKGPSRDWLGIVKSTQAKNKINQWFKKEFKESNIVKGKEMIAAYCKAKAITQSDIMINRYMEIVQKKYGFKDWESVLAAIGHGGLKEGQVVNRLVEEYGKEHKQEMTDEVVLERVAEASKNKVHIAKSKSGIVVKGIDDMAVRFSRCCNPVPGDEIVGFVTRGRGLSIHRTDCVNMIHLTEGERVRLIDAEWESEVAEQNGGQYLAEIKMFAHDRQGLLMEMSKIFTEATVDVKSMNVRTSKQGTATIETGFIVHGREELDTIVKKLRQVEGVMDIERTTG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_040434714.1|2294012_2296355_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	6.3e-11	38.6
WP_006442049.1|2296390_2296915_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.0e-22	35.7
WP_006442050.1|2297004_2298765_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	4.0e-79	31.7
WP_006442051.1|2298836_2301002_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	7.8e-24	33.3
WP_006442052.1|2301019_2302426_-	thioether cross-link-forming SCIFF peptide maturase	NA	NA	NA	NA
WP_006442053.1|2302506_2302650_-	six-cysteine peptide SCIFF	NA	NA	NA	NA
WP_006442054.1|2302733_2303108_-	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_040434715.1|2303161_2303710_-	stage V sporulation protein T	A0A2I7SC16	Paenibacillus_phage	1.5e-11	51.9
WP_006442056.1|2303905_2304352_+	GatB/YqeY domain-containing protein	A0A0K2FLI9	Brevibacillus_phage	9.4e-09	32.9