CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP043474	Mycobacterium grossiae strain DSM 104744 chromosome, complete genome	3 crisprs	cas3,DEDDh,casR,csa3,WYL,RT,DinG	0	1	4	0
NZ_CP043475	Mycobacterium grossiae strain DSM 104744 plasmid pGP01, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043474_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043474_1

1233864-1233941

Orphan

Consensus_repeat	Method
GTCCGGCTTGGCGTGCTTCGGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043474_1

>merge|NZ_CP043474|1|1233864-1233941|CRISPRCasFinder
GTCCGGCTTGGCGTGCTTCGGCGTGCTGGTGCTCGCGGCCGGCTCGGTGCCGTCGTCGGGCTTGGCGTGCTTCGGCGT

>NZ_CP043474|1|1|1233864-1233941|CRISPRCasFinder
GTCCGGCTTGGCGTGCTTCGGCGT	GCTGGTGCTCGCGGCCGGCTCGGTGCCGTC
GTCGGGCTTGGCGTGCTTCGGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043474.1\|WP_070352708.1\|1245839_1247444_-\|MCE-family-protein	unknown	unknown	gnl\|CDD\|273384
NZ_CP043474.1\|WP_070352723.1\|1226695_1227766_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070352714.1\|1239309_1239870_-\|mammalian-cell-entry-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070352721.1\|1228652_1229699_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236196
NZ_CP043474.1\|WP_070352712.1\|1240861_1241512_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070352710.1\|1243038_1244193_-\|virulence-factor-Mce-family-protein	unknown	unknown	gnl\|CDD\|273384
NZ_CP043474.1\|WP_070352709.1\|1244189_1245827_-\|virulence-factor-Mce-family-protein	unknown	unknown	gnl\|CDD\|273384
NZ_CP043474.1\|WP_149484214.1\|1225823_1226573_-\|DUF2786-domain-containing-protein	unknown	unknown	gnl\|CDD\|378525
NZ_CP043474.1\|WP_070352718.1\|1230999_1232343_+\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|225044
NZ_CP043474.1\|WP_070352722.1\|1227762_1228602_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|378820
NZ_CP043474.1\|WP_070352719.1\|1230245_1231022_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NZ_CP043474.1\|WP_070352711.1\|1241481_1243035_-\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NZ_CP043474.1\|WP_099045878.1\|1238011_1239025_-\|mammalian-cell-entry-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP043474.1\|WP_070352720.1\|1229726_1230173_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP043474.1\|WP_070352716.1\|1236536_1237310_-\|fructosamine-kinase-family-protein	unknown	unknown	gnl\|CDD\|225547
NZ_CP043474.1\|WP_070352713.1\|1239866_1240865_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP043474.1\|WP_070352715.1\|1237313_1238000_-\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|377734
NZ_CP043474.1\|WP_070352725.1\|1225299_1225818_-\|TIGR04338-family-metallohydrolase	unknown	unknown	gnl\|CDD\|275137
NZ_CP043474.1\|WP_070352726.1\|1223500_1224784_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP043474.1\|WP_070352752.1\|1232520_1233603_+\|phosphodiester-glycosidase-family-protein	unknown	unknown	gnl\|CDD\|378342

Protein	Function_ID	Function_description	E-value
NZ_CP043474.1\|WP_070352708.1\|1245839_1247444_-\|MCE-family-protein	gnl\|CDD\|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	8.00774e-72
NZ_CP043474.1\|WP_070352711.1\|1241481_1243035_-\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	8.31075e-69
NZ_CP043474.1\|WP_070352721.1\|1228652_1229699_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236196	PRK08241, PRK08241, RNA polymerase subunit sigma-70.	0
NZ_CP043474.1\|WP_070352710.1\|1243038_1244193_-\|virulence-factor-Mce-family-protein	gnl\|CDD\|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.39434e-84
NZ_CP043474.1\|WP_070352709.1\|1244189_1245827_-\|virulence-factor-Mce-family-protein	gnl\|CDD\|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.50712e-79
NZ_CP043474.1\|WP_149484214.1\|1225823_1226573_-\|DUF2786-domain-containing-protein	gnl\|CDD\|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	2.81946e-08
NZ_CP043474.1\|WP_070352718.1\|1230999_1232343_+\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	6.25279e-31
NZ_CP043474.1\|WP_070352722.1\|1227762_1228602_-\|alpha/beta-hydrolase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	8.04117e-93
NZ_CP043474.1\|WP_070352719.1\|1230245_1231022_+\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	3.18695e-67
NZ_CP043474.1\|WP_099045878.1\|1238011_1239025_-\|mammalian-cell-entry-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	3.48985e-09
NZ_CP043474.1\|WP_070352720.1\|1229726_1230173_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	3.96346e-13
NZ_CP043474.1\|WP_070352716.1\|1236536_1237310_-\|fructosamine-kinase-family-protein	gnl\|CDD\|225547	COG3001, COG3001, Uncharacterized protein conserved in bacteria [Function unknown].	1.87794e-45
NZ_CP043474.1\|WP_070352713.1\|1239866_1240865_-\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.74169e-13
NZ_CP043474.1\|WP_070352715.1\|1237313_1238000_-\|DUF1275-domain-containing-protein	gnl\|CDD\|377734	pfam06912, DUF1275, Protein of unknown function (DUF1275). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.	9.81375e-30
NZ_CP043474.1\|WP_070352725.1\|1225299_1225818_-\|TIGR04338-family-metallohydrolase	gnl\|CDD\|275137	TIGR04338, hypothetical_protein, putative metallohydrolase, TIGR04338 family. This protein family is restricted to the Actinomycetales, including Mycobacterium, Rhodococcus, Nocardia, Gordonii, and others. The invariant motif HEXXH, at the core of the best conserved region in the protein, suggests metallohydrolase activity, as does local sequence similarity in this region to other metallohydrolases.	3.22768e-63
NZ_CP043474.1\|WP_070352726.1\|1223500_1224784_-\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.15282e-22
NZ_CP043474.1\|WP_070352752.1\|1232520_1233603_+\|phosphodiester-glycosidase-family-protein	gnl\|CDD\|378342	pfam09992, NAGPA, Phosphodiester glycosidase. This is a family conserved from bacteria to humans. The structure of a member from Bacteroides has been crystallized and modelled onto the luminal region of the human member of the family, the transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. There is some conservation of potentially functional residues, implying that in the bacterial members this family acts in some way as a phosphodiester glycosidase. The human protein is also present, so the eukaryotic members are likely to be catalyzing the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides.	0.000211684

>NZ_CP043474.1|WP_070352752.1|1232520_1233603_+|phosphodiester-glycosidase-family-protein
MSRPAAKLRRLVSCTTTLLLCASLQTVTHAPLARAADGAGLLASAIAATRGTYLVYHFGASHPAPMRNAAGDSYEMPSGGHLMIVKAASQRLTPRLLVDSHRGYQARCERDPRARTAEGLLQASEVFTPVQAWQALGQPTLAINANFFDVRGQAGGSWKTTGCSSPLGAYVDTTRGQGQANAAVTGTVPYAGKQGLSAGNETWTALHTMILPVAGAPFVVAPRSADDFDAAGPVIADLMAKGVRFVAVAGLGLLAPGDTGQLNDGGPSAARTALAYSREKDEMYVFQGGSHTPDQLQDLFRALGSDTAILLDGGGSSAIVLRREAGGMWAGAGVPRGSCDTQQVLCDSRERALPSWLAFS
>NZ_CP043474.1|WP_070352718.1|1230999_1232343_+|PQQ-dependent-sugar-dehydrogenase
MRVWLRHSRSAIALGAVALMVAACSSSASDSPNGSSGASSSDESSSAETSSPAGASAAGLEQVTVQVPDDLRAAPFDAPRTARVPQGWTLSVWARTPKPRLLAWTPDGALLVSVPSTGEVLRMQPTGAGPQEDVLLSGLDQPHGMAFAGSTLYVAESDQVDAYDYADGRATNPRTVAAGLPDARSPDLRGAYSHALKSVAVGPDGAVYFSIGSTGNVSAEDRTATPPRATIMRIPPGGGPAAPFATGVRNGTGLAVAPDGTVWTAVNNRDNVAFPEEGPQYGQVVPDYVDENPPESLAKVTPGRELGWPYCNPSGGPANLAFIRDVQTNADGTKLDCAALPPVEQSFGAHSAPLGLGFVDGQLPAPYAAGALAGVHGSWNREPPRAPEVSFFPWRDGGLGDQQTLIGGFQGDDGSRWGRPVAAVVSPDRAVYVSDDYADAIYRLSPP
>NZ_CP043474.1|WP_070352719.1|1230245_1231022_+|pirin-family-protein
MATAEKTAENVEIRRAADRAATKISWLDSKHSFSFGGAYDPANTHHGLLLVNNDDIVTPGSGFDTHPHRDMEIVTWVLRGSLVHQDSTGHSGVIYPGLAQRMSAGRGILHSEKNDSWTLTGEASHAEPVHFVQMWVVPDESGITPGYQQLEIDDELLRGNLVTIASGMPEHAGDTAITIRNRYAALKGARLAPGDTVELPQAPYLHLFVPRGEVTLEGAGTLNEGDAVRFTASGGQRVTATEPSEILVWEMHASLAAA
>NZ_CP043474.1|WP_070352720.1|1229726_1230173_-|winged-helix-turn-helix-transcriptional-regulator
MYSVWLSDDEQRLWRDYLTMSGRLQAAMNRQLQRDNGLSLADYEVLVALAELADCRISDLGERLGWEQSRLSHQLTRMRGRGLIARRGASDDRRAATVALTDAGRAALDAAAPGHVELVRSVVFAGTSATDLRALSRWTAAVLRRLEE
>NZ_CP043474.1|WP_070352721.1|1228652_1229699_+|sigma-70-family-RNA-polymerase-sigma-factor
MRRSPWVGSAGVSVLAEIPDLPESFDSKDDFLAGAQRYRRELLAHCYRMTGSLHDAEDLVQETYLRAWKSYEGFQGRSSVRTWLYRIATNTCLTSLDGRKRRPLPSGLGQPSSDPTGDIAEHREITWLEPLPDAPKEDPSDPSVIVESRESVRLAFVAALQHLSARQRAVLVLREVLQWKAAEVAEAIGTSTAAVNSLLQRARAQLDAVRPSEDGDVVAPDSREAGEQLARYVAAFENYDMDELVKLFTADAIFEMPPFDGWYQGPADIVTLSKTHCPAQGPGDMRFLATTANGQPAAALYMLNRETGRHEEFQLHVLEVRPGGVSHVVAFHAGEGLFARFGLPDVLV
>NZ_CP043474.1|WP_070352722.1|1227762_1228602_-|alpha/beta-hydrolase
MSATRTEREFSGVGSVRIVYDVWTPDGPPRGVVVLCHGYAEHAGRYGHVAARFGAAGLVTYALDQRGHGRSGGKRVRLNDISEYTGDFRTLMGVAAAEYPDLPRIVLGHSMGGGVVFTYGTEHPGDYAAMVLSGPAVHAQDGVSSMKVRLAKVVGRVLPGLPVEKLPADAVSRDPAVVAAYEADPLVHHGPLPAGIAKALIEVGETMPRRAGALTAPLLVVHGDADALIPVSGSRLLMECVGTDDAHLKVYPGLFHEVFNEPERDLVLDDVVSWIESHL
>NZ_CP043474.1|WP_070352723.1|1226695_1227766_-|hypothetical-protein
MRVALRRARAAVAVALVALPLAVGCSSAPEAAAPSTPNPGWTDEDVTFDADGLTLHGTYRHRGDAAPGPAALLISESGNTDRNGDNAVAGPVGNMRQLAEYLSDHGVASLRYDKVGTGKTGLGPYAARPADVGSAVYTAGAKSAARFLAGQTRTDKTRISVYAVGEGTVHAMALATDTAADALKVHSLALLQPLSGRYLDIISGRVHTDVDSAVASGAKTRQQGDDVLAAWAAAVDEARTRGTAPAKLPEGLGAILNPGNVKAVVEADAIDPQALAAKVPAGTPVLATCSDSDAQADCATEKPLFDALRRTALTVVELKGVNHVLRDDPTDSVANYAKKAPLSPQLTTALDAFVGR
>NZ_CP043474.1|WP_149484214.1|1225823_1226573_-|DUF2786-domain-containing-protein
MSDPKMLARIAALLRQAENTENAHEAEAFMAAAQRLATTTSIDLAVARAHAATRTAVQTPTQRTITIGDAGTRGLRTYVQLFVGIAAANDVKCDVASNSTFVHAYGFAEDIDATHALYASLVLQMVKASEAYIDSGAHRPTPTITARLNFQLAFGARVGARLADAREEARQQAAATRDDQPGTALALRNKDIELTSFYRTASKARGTWRASSASAGYSSAARRAGDRAGQRASLGPSTELSGARGALDR
>NZ_CP043474.1|WP_070352725.1|1225299_1225818_-|TIGR04338-family-metallohydrolase
MARDAQRARVYAAEEFVRSLFDRAQSRSGATVDFFGATLTLPPEARFGSVTSVRTYVAGVLGHPAVRERWPDAPPLAVRTRRGSTAAHYEVRDGRAAIAVPDGAAVSAVAGGSAPWALRELVVLHEIAHHLCGAEEAHGPEFVATFTDLADAVMGPEVGYVLRVVYAKEGAR
>NZ_CP043474.1|WP_070352726.1|1223500_1224784_-|MFS-transporter
MAERVASRQSLRGLDALNFFLADVRDGLGPYLAIYLIAVRGPSHGWNEATVGAVITTAGIVGLIFQTPLGGLVDKVAQRRLVVVVAASMVTVSCLVLPFVSGFALVTATQSIASIAGAAVAPAISAITLGLVGPKLLAPRIGRNEAFNHAGNAASAGIAALLAWWLGPVVVFWLMGVLAVCSIVSTLRIRATEIDERQARGLTASAGDDAAGGAPGVSGLRVLLTSRPLLVFTIIAFTFHLSNAAMLTSVSQLLTRVVGKDGATSLVALCVLAAQLVMIPVAILVGRKADVWGRKPIFLAAFGVLAARGLLYTVSDNGTWLLVVQALDGVGAGIFGALFPVVVADLTRGTGRFNLAQGAVATSQGLGGALSAGLAGAIIVALGYDVAFWTLAGIAVVGLVLYATLMPETRPAPGGTPETGAAKAATG
>NZ_CP043474.1|WP_070352716.1|1236536_1237310_-|fructosamine-kinase-family-protein
MHIFRKTNPSAPPGLFAAEAHGLRWLGAVSGGVPCARVHSFDETGLDIERLERVRPHADAARQFGRRLAVTHAAGADAFGSPPDGWSGPGYFGPAERPLPMSYGAYASWGAFLAEERLGPALDAAAPTLAAGTRRDVATVIDRARAGDYDDDATPSRLHGDLWNGNVLWTPRGVVLIDPAAHGGHHETDLAMLALFGCPHHDAVIEGYQEHRPLRPGWQVRRGLHQLYPLLMHVALFGAGYAASVTEATRSALAARG
>NZ_CP043474.1|WP_070352715.1|1237313_1238000_-|DUF1275-domain-containing-protein
MQSPVSDRATVAALLLLTFATGLVDAVSVLVLGHVFVANMTGNVIFLGFWFVPHSGVDLTAAVVAFASFVTGTVLGGRLARHLDVRVRRWLLVALGIEVVMLTVLAVLAGTGVLSYHDNGKLVLIAGLAVTFGMQNATARQFGIQELSTTVLTSTIVGIGFDSRLAGGTGQREKLRYGVVLTMLGGAVLGATLTRVTVAPVIGLAAAAVAAGAAVFAYGPAPARATAD
>NZ_CP043474.1|WP_099045878.1|1238011_1239025_-|mammalian-cell-entry-protein
MAPSEAPAETVTPEPAAAEPAAKSTTAEPQTAEPTTTRRRFGWGRKKAAPAAPVVTETPDAVPDPSPLDTTPASTAPADTTPVDTAPVDTTSAEDVAAAPADETETDVVTTAAVADTTVAPEADDVDPVSTEDAESTETAETSEAPESAATSEADEAPEPVLVPHRTAGRALKVAAAAAGVLVVGAAAFAGAALQPYLADRAEVQTKFEIAKVSADAITTLWTYTPEDMDSLPDRAARYLGGDFATDYRRYIDSIVSTNKQAQVSNVTQVMGTAVEDLSPTEATALVYTNSVATSPVTKGIPSLRYLSYRLGLRLEDRKWRITQMQAVTSLDLTPRL
>NZ_CP043474.1|WP_070352714.1|1239309_1239870_-|mammalian-cell-entry-protein
MSPRRLVDPTDRDYFAAPMSAPKGPRRWGLPVTAVVSALLAIAAIVGCVFVAVNHESTRRTDLRDAAALGYVREFMVRYTSLDPFNANQYVDDILGQATGEFATSFKERSNEIVIQVARTEPTKGDVLAAGVERWNANGSADVLVAANVTTPGRDGRPTVESASRWVATTIEEGEQWKISKLVQVI
>NZ_CP043474.1|WP_070352713.1|1239866_1240865_-|RDD-family-protein
MTAVLPDREAPTSAAPDARYAGWWARAAALAVDVVPALAVIAAMALIAVASPLRGWVWWTVTVVAAVAFVLAAANRWVFPAVRGWSLGRALVGARIVTRDGAPAGTVRLFLRDLVHLLDTALVFVGWLWPLWDRRHRTFADMVLRTESHRVAPTGAADPDDAVRRTDVRRRVGAVLLIAALLCVAGGALGYAFVFRPERGIESARNQLADQGPRIVEQMLSYGAATMQDDFAKSQALATSAYRPQLTEQQQAAAKVGATTNEYWATNSAVLSASPDHGVLLVALQGQRGNDPTTVKFISATVQVEFQKTDDRWLVANLTVLKKPNAAAGAGG
>NZ_CP043474.1|WP_070352712.1|1240861_1241512_-|hypothetical-protein
MEGDAGPGRLNPTDSQDTADDASVAPAVTPLDADADYPVDAEDRPTDGRRAERFGRAWVASIAVALVLVAGAVAAGGVVALRAHQKSQDYVRADAAAVAAAKDCVTATQAPDTAVMSASQAKIIDCSTGDFGTQAMLYSGVLADAYQAANVKVQVTEMRAAVEKHGDGGTVDVLVAMRIKVSNLQVADQEQGYRLRVQMAPEDGTYKIAKLDQVAS
>NZ_CP043474.1|WP_070352711.1|1241481_1243035_-|MCE-family-protein
MLTRVIRIQLIIFTVLTLIALGVLGLYYLKLPSLVGIGQYELKAQLPRSGGLYATANVTYRGTTIGKVTDVVPTESGAQATMSIDSQYKIPVDVTANVHSVSAIGEQYLDLVPSEENGQFLANGATITKSTVPSEVGPALDAANEGLAVLPKEKIDSLLTETSKAVGGLGPALQRLVDSTTNLAQGFDENLPQVNDIVDNSAPILESQVLSGDAIGQWARNLDTIAAQTAEQDAALRTGLQQAAPTADQVSAFFSSVKDSLPQTLANLSIVLDLLKKQNKGVEQLLVAFPQAGAVGQMGTIFDGQALLPLALGINQPPPCLTGFLPASQWRSPADTTTAEIPKDVYCKIPKDFQGNAVRGARNYPCLDVPGKRAATPAECRSNEPYTPAGTNPWYGDPNQVLTCPAAAARCDQPVKPGYVIPAPSVNNGLNPLPASQLPPPHSQVPSSDPLTAPGQGSVSCSGQQPNPCIYTPASGPTAVYNPSSGEVTGPDGVKYTVDNSSNPGENGWKEMLAPAG
>NZ_CP043474.1|WP_070352710.1|1243038_1244193_-|virulence-factor-Mce-family-protein
MTKLRWPGTRTLLKRAGVLSVAAVVLTSCGWQGIANVPLPGGPGSGSDKMTIYVQMPDTLALNVNSRVRVADVFVGSVRSIELKNWVATLTLDVQPGIELPANTTAAIGQTSLLGSQHVQLDPPADPEGRLKSGDTIPLDRASAFPTTERTLASIGAILSGGGIPNLETIQNELSNVLTGRGDQIREFIGRLDTFTAELNAQREDITRAIDSTNRLLSIVAQRDDTLDRVLTEFPPLIKHFADTRDLFGDAVESLGRISKAADAALSPISADLKTNLQNLQRPLKQLGRASPYLIGALKFMLTAPFPIESADKAVRGDYINVSLNVDLTLSSVDNGILTGTGLSGALRALEQSWGRDPNTMIPDVRFTPNPHTVPGGPLVERGE
>NZ_CP043474.1|WP_070352709.1|1244189_1245827_-|virulence-factor-Mce-family-protein
MSTIFNVRNVKLPRLSRASVILGTIVIIVAVALAFLGWNLYQRLTKTTVTAYFSQTLALYPGDKVQIMGVRVGAIDEIEPAGDKMKVTFHYDSKYKVPQDATASILNPSLVASRAIQLSPPYTGGETLKNDAVIPLERTQVPVEYDDLRNSLDRILTDLGPTPEQPKGPFGDVIESFADGLAGKGEEVNRALNNLSEALSTLNQGRGDLFGVIKSLALFVNALHRSDQQFVALNNDLATFTNSFTNTDREVANAVRDLNVLFTNTRQFFDENGEVLGKDIGNLADVTNAIVQPEPFNGLETGLHVFPTLAINALNIAAPVPGGVTSLPVIGNFANPLQFICSSIQAGSRLGYQESAELCAQYLAPILDAIKFNYLPFGLNQFSSALTLPKQIAYSEPRLQPPPGYKDTTVPGIFSRDTLFSHGNHEPGWVVAPGMQGVDVQPFTANMLTPDSLSALLGGPDPSYIPPGGPRGGAPPNSYDQNNPLPPPWYPQPGPPPAPAPGVIPGDPLSAISAPAAPGPGTGPAPAPAAVPSGPLFPAEAGGTP
>NZ_CP043474.1|WP_070352708.1|1245839_1247444_-|MCE-family-protein
MRTLEGDNRVRNGLKGILILLLVIGVGQSFASVPMIFAQPVYYAEFKDTAGINGGDKVRIAGVDVGEVRSTGIDGDKVVVGYTLNGTRIGTESRAAIRTDTILGRKNIEIIPKGSNTLPPNGTLPLSQTTTPYQIYDAFSDLAEAGLGWDTKTIKQSLNVLSETIDQTYPNLSAALDGVARFSDTIGKRDDDIQKLLANANKVAGVLGNRSGQINALFVNTQTLLGAINERNTAVSALLERVSAFSQQVAGFTKDNPNLNKVLEQLRTISDVLVARKYDLMDVLSNVSKVATALGEAISSGPYFKVILINILPYQIIQPWVDAAFKKRGINPEEFWRNAGLPEFRYPDPNGQRFENGAPPPAPTPLEGTPEHPGPAVIAGSPCSYAPAAGNFPTPANPLPCTQAENGPFGPNPYGSNNYGPPDVLGLPPNPNAPPPAPGVPAAAFPGEYSPPVQGTPPPPFVPGPPGARTVPVTPGPADPYIAPGSLQGDGTSPLPPPLTGPPPPPGPGPQLPPVDTPPLPGNPPFLPPGSQDQ

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Crispr_ID: NZ_CP043474_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043474_2

1309733-1309839

Orphan

Consensus_repeat	Method
GGCTACGGCGAGCAGGGTTACCCGCCGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043474_2

>merge|NZ_CP043474|2|1309733-1309839|CRISPRCasFinder
GGCTACGGCGAGCAGGGTTACCCGCCGCCGTCCTACGACCAGCGGCCCCCCGCCGGTGGCGGCTACGGCCAGCCCGGTGGCTACGGCGACCAGGGTTACCCGCCGCC

>NZ_CP043474|2|2|1309733-1309839|CRISPRCasFinder
GGCTACGGCGAGCAGGGTTACCCGCCGCC	GTCCTACGACCAGCGGCCCCCCGCCGGTGGCGGCTACGGCCAGCCCGGT
GGCTACGGCGACCAGGGTTACCCGCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043474.1\|WP_070356058.1\|1312717_1314130_+\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|279444
NZ_CP043474.1\|WP_070355122.1\|1321235_1321763_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NZ_CP043474.1\|WP_070356050.1\|1303909_1305691_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP043474.1\|WP_070355132.1\|1319465_1320179_-\|DUF881-domain-containing-protein	unknown	unknown	gnl\|CDD\|226396
NZ_CP043474.1\|WP_070356054.1\|1307835_1308642_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_CP043474.1\|WP_070356048.1\|1301925_1303368_+\|neutral-zinc-metallopeptidase	unknown	unknown	gnl\|CDD\|225203
NZ_CP043474.1\|WP_070356046.1\|1300352_1300856_-\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274679
NZ_CP043474.1\|WP_170292400.1\|1301247_1301658_-\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|366782
NZ_CP043474.1\|WP_070356052.1\|1306476_1307229_-\|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|172294
NZ_CP043474.1\|WP_170292401.1\|1307511_1307811_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|366782
NZ_CP043474.1\|WP_070356051.1\|1305694_1306414_-\|phytanoyl-CoA-dioxygenase-family-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070356049.1\|1303470_1303671_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070355124.1\|1320371_1320656_+\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907
NZ_CP043474.1\|WP_070355125.1\|1318754_1319420_-\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|181107
NZ_CP043474.1\|WP_070356056.1\|1310718_1311183_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224630
NZ_CP043474.1\|WP_070355126.1\|1316902_1318777_+\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP043474.1\|WP_070356059.1\|1314126_1315602_+\|D,D-transpeptidase-PbpA	unknown	unknown	gnl\|CDD\|223839
NZ_CP043474.1\|WP_070356047.1\|1300984_1301218_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070355123.1\|1320784_1321216_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|371225
NZ_CP043474.1\|WP_070356057.1\|1311179_1312721_+\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704

Protein	Function_ID	Function_description	E-value
NZ_CP043474.1\|WP_070356058.1\|1312717_1314130_+\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|279444	pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE.	4.85569e-95
NZ_CP043474.1\|WP_070355122.1\|1321235_1321763_-\|peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	1.56799e-65
NZ_CP043474.1\|WP_070356050.1\|1303909_1305691_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.00993e-54
NZ_CP043474.1\|WP_070355132.1\|1319465_1320179_-\|DUF881-domain-containing-protein	gnl\|CDD\|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	1.07666e-61
NZ_CP043474.1\|WP_070356054.1\|1307835_1308642_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.00296343
NZ_CP043474.1\|WP_070356048.1\|1301925_1303368_+\|neutral-zinc-metallopeptidase	gnl\|CDD\|225203	COG2321, COG2321, Predicted metalloprotease [General function prediction only].	4.52186e-27
NZ_CP043474.1\|WP_070356046.1\|1300352_1300856_-\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	6.24348e-28
NZ_CP043474.1\|WP_170292400.1\|1301247_1301658_-\|STAS-domain-containing-protein	gnl\|CDD\|366782	pfam01740, STAS, STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.	7.53278e-06
NZ_CP043474.1\|WP_070356052.1\|1306476_1307229_-\|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl\|CDD\|172294	PRK13756, PRK13756, TetR family transcriptional regulator.	7.21732e-11
NZ_CP043474.1\|WP_170292401.1\|1307511_1307811_+\|STAS-domain-containing-protein	gnl\|CDD\|366782	pfam01740, STAS, STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.	2.51904e-10
NZ_CP043474.1\|WP_070355124.1\|1320371_1320656_+\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	1.72016e-46
NZ_CP043474.1\|WP_070355125.1\|1318754_1319420_-\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|181107	PRK07765, PRK07765, aminodeoxychorismate/anthranilate synthase component II.	1.86136e-146
NZ_CP043474.1\|WP_070356056.1\|1310718_1311183_+\|FHA-domain-containing-protein	gnl\|CDD\|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	1.45028e-27
NZ_CP043474.1\|WP_070355126.1\|1316902_1318777_+\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.31763e-126
NZ_CP043474.1\|WP_070356059.1\|1314126_1315602_+\|D,D-transpeptidase-PbpA	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	4.16448e-99
NZ_CP043474.1\|WP_070355123.1\|1320784_1321216_+\|PH-domain-containing-protein	gnl\|CDD\|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	8.84732e-08
NZ_CP043474.1\|WP_070356057.1\|1311179_1312721_+\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	4.41043e-83

>NZ_CP043474.1|WP_070356054.1|1307835_1308642_-|hypothetical-protein
MGNKRSSDGGGTVGGFIVGVIVLVALVPKPVWIALGVCVAAALLIWLVSALVAADRKRRAEAEERERAERIERAAAAKREREDRARREKQARIDALGKDNAALVEKALHSVTVVTGSEAARKGWLGDVDFSADIAGINDAFGKAHALRGVTDRLSALDKPSADDRRILAEARTTIAGLERTACERVELIAKCAREAQLVDRCLRAERTDARVAEERAQLHGQLSAMLYGVEATPTPDPADSTAEVVRTRVRAYLEIKNQIDRTRGVDR
>NZ_CP043474.1|WP_170292401.1|1307511_1307811_+|STAS-domain-containing-protein
MLRVRGDVDISNLASWRCVLAEASNATAPDGVLVVDVDAAGFLGLCTFTALAVLSEVCRRRDIALRLVSAKPSIARIVALCQWQNELPVFPTVSAAVDE
>NZ_CP043474.1|WP_070356052.1|1306476_1307229_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MAGGQGVGRRRAKDEVGDGAVSGDQSTPRLTRPVILDAAIAFIDEHGLDRLTMRRLGQTCGVEAMALYRYVHSRGDLLTGIVDHVLDQLYTDQLAARRQEDGWQDYLLRLAHGVRQIALHHPQVFPLVATAAPEAPWVRPPLRSLRWMESFLDTLISYGFTDETAVTAYRTYTSFLVGQLLQEVSARGAELHRDEAVVEEADPKTPIMDLSEYPNLQRLEPALSEDHSAAEFEDMLEAILDRLELLVARH
>NZ_CP043474.1|WP_070356051.1|1305694_1306414_-|phytanoyl-CoA-dioxygenase-family-protein
MIDVDAFLADGVARLEQPSLRDVADAARAALWAQLGMSPDDPAGWTTPVAWAADLTGDGPFGALVHSPAVAEALDQLCGVGGWQPRGALGNVPVRFPVAPAADDRGWHLDANTPAGDGSWCVTGRPHTLLVLTLLSEVGPDDAPTRLRVGSHHDVAAVLGNRQWDPFDAGPVVDAASAHRPIARATGRPGDVYLVHPFTVHAADEHRGSTPRFMAQGPVMLAAPLSPDDPTPLARALHG
>NZ_CP043474.1|WP_070356050.1|1303909_1305691_+|diguanylate-cyclase
MQVGELEQADSVESMAVLAGFPAACPRTGIVVQDPAGSILAVSPGAESILGMTLAQMLGRTSQDRRWASVDEDGQPVSGADHPAMRALRLGVPVRGATLGVHRPGSEAPGRHVWLTVESVPLLQPADPRPYAVVTAFRAVRGERLKDLELRDSERFYRMLGEHSSDMVAWQLLSDSTYLWASPATKSVLGLEPDEVIGMSGLDLIHPDDRGAKERWRQRIAAGDRVAPVTLRMRHTDGGYRWIETTAHVLPSAGGPPTQVITTRRDITDRVETEAARDDAIRLFEMAFEHATIGIALRDLDGTLSRVNPALCTMLGRREGDLRGCRLADFALPGEAAPANPRRGGDRREVERRFRRPDGSVVWCLETIVALPDADGAPSHLLVQLQDITQRREVAAQLERAALTDSLTGLSNRVVLEDRLARALVTARRCGHRVGVLFIDLDDFKRINDTLGHEAGDRMLREVGTRLATAVRHDDVVVRLGGDEFVVVRERIAGAADLRGLVERIRGILARPFAIAGLQLPLTASIGVTAGADGTADELLARADRAMYRAKRRRGSGRRRFAVVVDGDAPGSFAGVRDGWRALRASRERHALR
>NZ_CP043474.1|WP_070356049.1|1303470_1303671_+|hypothetical-protein
MKKFGFTTLVAGGLAAAVLGLAGPAQADAISVVQTVPAGIDHHYWLDDTQQQANTPHVDTTVHQSR
>NZ_CP043474.1|WP_070356048.1|1301925_1303368_+|neutral-zinc-metallopeptidase
MKRRVGIIVAACAVLLVAGCSSVTQGRAVSTLYDPFRAGGLAAQDGPSGIKDDAPAPAGEVEGSDGGGVDALGLLAVDDIAEYWQQNYAESLEGQFAPIERLQSYDSNDPSSPSICGTDTVGEPNAFYCPRRDLMAWDRGVMVPTGREFFGDVAIAALIAHEYGHAVQHMAGLVTDDTPVIVLEQQADCFAGSYVRWVAEGESTRFRLSTGDGLNHVLAAAITLRDPVLGPGDEAMLHDGHGTAFDRVSAVQMGFVGGPSECAVIDLDEIEQRRGDLPMALPVDGDGAVRAGDVDLDEDTLSAMMDTLGEVYRPASAPTLSYGPAPCPDATPVPPVSYCPSTNTIGVDLAALGRLGAPADESNYVLLQGDNTALSVLTSRYALAVQHEAGLGLDTPAAALRTACLTGVAQAAMADADESPGGGGLVLTAGDLDEAVAGLLTNGLAASNVDSQTVPAGFTRIVAYRSGLSGDRDLCLARFP
>NZ_CP043474.1|WP_170292400.1|1301247_1301658_-|STAS-domain-containing-protein
MTTMGNLELCEGALVRAYSRRLATVVSVSGEIGDGNEERLAARVGRHVLDDAVVLDLGGLTAVSEQGRHLVERVYDVCRAAGVDFAVVAADDVTATMNLVDAPYPVVRSVPDALRCFADFTGARRQVLLPLLGKIA
>NZ_CP043474.1|WP_070356047.1|1300984_1301218_+|hypothetical-protein
MIEDAAASQARLLLATLSAQVADCTTRLSVVEGRLQRRTYCASTDRRQRHDLRRELTEMQRLIANLHDRFPHLAAPA
>NZ_CP043474.1|WP_070356046.1|1300352_1300856_-|PPOX-class-F420-dependent-oxidoreductase
MGRNERAKIVMSDDEIADFIDHSRTATLATVSPGGRPHLVAMWYAVLDGEIWFETKAKSQKAVNLRRDPTVTVMIEDGLTYDTLRGVSIDGRAEIVDADPDVLHRVGVSVWKRYTGPYSDDVKPFVDQMMNNRIAVRVVPTRLRSWDHRKLGMPEMPVGGTTAQYLR
>NZ_CP043474.1|WP_070356056.1|1310718_1311183_+|FHA-domain-containing-protein
MQGLVLQLTRVGFLLLLWLFIWSVLRILRTDLYAPTGAVMVKRGLALRGTLLPNRQRNVARQLVVTDGALAGTRITLGTQPVLIGRADDSTLVLTDDYASTRHARLSPRGNEWYVEDLGSTNGTYLDRAKVTTAVRVPMGTPVRIGKTAIELRP
>NZ_CP043474.1|WP_070356057.1|1311179_1312721_+|serine/threonine-protein-phosphatase
MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLNQLNEAVHEGNAAIAAHVEADPELEGMGTTLTAILFAGNRLGLVHIGDSRGYLMRDGELSQITKDDTFVQTLVDEGRITAEEAHSHPQRSLIMRALTGHEVEPTLIVREAKAGDRYLLCSDGLSDPVSRDTIAEALQIADVAESADRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDDDQTAPPNTAAGRASAFNPKRAAPAKRPAVEPEPPPKKPRSRRTMLIAVILLVLLIGAGLAVGRMMIRSNYYVAEHDGAVYIMRGVQGSLLGFPLQEPYRVACLDDRNGLRIIGVDDARTDCELLEIGDLRESERAQVAAGLPTGSVDDAIRQLRDLAASSLLPICAPPRPATTTTAAPPPTSGAPSTSGTPTASGTPATTSPSRGPLPGPAPETPTTVTSPPTADDPNASTPPPAPSPTVTALPPSPQEPGTTCRAAS
>NZ_CP043474.1|WP_070356058.1|1312717_1314130_+|FtsW/RodA/SpoVE-family-cell-cycle-protein
MTTQPQAAVTVVPPMPTRRNAELLLLGFAAVITMVALLLVEANQEQGLSWDLLQYLVGYVALFAGAHLAIRRFAPYADPLLLPIVALLNGLGLVMIHRLDLTAPLDAGAAPGPSANQQMLWTLVGVIGFAAVVAFLHDHRMLAKYGYVCGLTGLVLLVIPALLPRSMSEQGGAKIWIRLPGFSIQPAEFSKILLLVFFASVLVSKRSLFTSAGKHVLGLNLPRPRDLAPLLAAWIASIGVMVFEKDLGTSLLLYASFLVLVYVATDRISWVLLGLGLFAIGSVAAYYAFGHVRVRVQNWLDPFADPDGAGYQMVQSLFSFATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGFAGVLMLYTIVIVRGMRTAIAVRDSFGKLLAAGLAATLGIQLFIVVGGVTKLIPLTGLTTPWMSYGGSSLLANYVLLAILIRISHAARRPITTKGPTPGPIASASTEVISKV
>NZ_CP043474.1|WP_070356059.1|1314126_1315602_+|D,D-transpeptidase-PbpA
MNTSLRRISLALMVLVILLLGNATLTQVFTADGLRSDPRNQRVLLDEYSRQRGQITAGGQLLAYSVATDGRLRYLRVYPNPLAYAPVTGFYSLRFSSTGLERAEGPILNGSDERLFGRRLADFFTGRDPRGGNVGTTINPDVQEAAWDAMAQGCGGPCKGSVVALEPSTGKILAMVSAPSYDPNLLASHDVEEQSAAWERLRDDPESPLVNRAISETYPPGSTFKVITTAAALANGATPDTQLTSAPRIVLPDSTSTLENYGGTSCGSGPSTTLREAFARSCNTAFVQMGIDTGADKLREAARGFGVDQPTVPIPLQVVESTLGPISDAAALGMSSIGQKDVALTPLQNAMVAATVANGGVAMTPYLVSDLRGPDLSNVATTTPTEARRAVSSQVATTLTDLMIGAEQVTQQKGAIAGVQIASKTGTAEHGTDPRNTPPHAWYIAFAPAKAPKVAVAVLVENGGDRLSATGGAVAAPIGRATIAAALREGS
>NZ_CP043474.1|WP_070355126.1|1316902_1318777_+|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTTPQHLSDRYELGEILGFGGMSEVHIARDVRLHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVYDTGEAETANGPLPYIVMEYVDGVTLRDIVHTEGPIPTRRAIEIIADACQALNFSHQHGIIHRDVKPANIMISKAGAVKVMDFGIARALADAGNSVTQTAAVIGTAQYLSPEQARGEKVDARSDVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPTPPSQRHEGISPELDAVVLKALTKNPDNRYQTAAEMRADLIRVHSGEAPEAPKVFTDAERTSMLTAPATAHGGRHAPTERIPAHRPNDARNRSIRRWVIAVALLAVLTVVVTVAINMIGGAPRDQQVPDVAGQSIQDATATLQNRGFETRTDEQADSKVLPGQVIGTDPESGTAVAAGDLIVIKVSSGPEQKVVPDVKTMTPEQASARLREEEFTNIKVTESASLPEQKGRVLETSPPANSTSAITNQIILIVGSGPGSKGVPDCAGLTATDCENILRANEFPNFVQVQVDNTRAAGQVVSTNPPALQDVPVDTVIQIQVSRGNQFLMPNLRGQFWDDAYPQLASLGWTGTLVKLPNAQNSGVPSNGVVTQDPAPGTPITFGAPITLSFAQ
>NZ_CP043474.1|WP_070355125.1|1318754_1319420_-|aminodeoxychorismate/anthranilate-synthase-component-II
MQVLVVDNYDSFVFNLVQYLGQLGVTAQVWRNDDARLADADGVAGDFDGVLLSPGPGTPERAGASIALVEACASSATPLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSVVHHDDLGVLRGLPDPFTATRYHSLTILPETLPDELTATAHTEGGVIMAVQHAELPIHGVQFHPESILTEGGHRMLANWLTLCGIAPDETLVRQLEQEVADTVRAATARSSA
>NZ_CP043474.1|WP_070355132.1|1319465_1320179_-|DUF881-domain-containing-protein
MPIVCLCAGLLLATTHTVSGGGEIRRSDAPRLVDLVREAQQSVDRLTAQRDALVGEVDNHHGGSPSADAALTVITGRADTLAVDAGVAPLRGPGLVVTLNDAQRDAEGRFPGDASPDDLVVHQQDVQAVLNALWSAGAEGIQMQDQRIIGTSAPRCVGNTLLLNGRTYSPPYVITAVGDVGAMQAALAAAPLVTLYRQYVVRFGLGYSEEARGRVDLAGYDAPLRMRYAKPAGPLGY
>NZ_CP043474.1|WP_070355124.1|1320371_1320656_+|cell-division-protein-CrgA
MPKSKVRKKNDFTVNPVSRTPVKVKAGPSSTWFVALFIGLMLIGLVWLLVFQLAATNPVDAPGFLTWMADLAQWNYAIAFAFMITGLLLTMRWR
>NZ_CP043474.1|WP_070355123.1|1320784_1321216_+|PH-domain-containing-protein
MQQTEWGPRPAAVVVCGLLGVVLLIAAVTLVTDVPGRFLASVAGIGLVAFAVLSWRARPKLAIGADGLVVRGWFRTRTLRRADLAAVRITEFRRIGRKVRLLEIDTTPDDDLLVFTRWHLGAEPLAVLDVLTEAGYVPETRAR
>NZ_CP043474.1|WP_070355122.1|1321235_1321763_-|peptidylprolyl-isomerase
MTSPIQTATATLHTNRGDIKIALFGNHAPKTVANFVGLAQGTKDYSTENATGGASGPFYDGAVFHRVIAGFMIQGGDPTGTGRGGPGYQFDDEFHPELQFDKPYLLAMANAGPGTNGSQFFITVGKTPHLNRRHTIFGEVVDPESQKVVDAIATTDTDHGDRPTEPVVIESVTIS

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Crispr_ID: NZ_CP043474_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043474_3

5280139-5280229

Orphan

Consensus_repeat	Method
CTGGCCATTGGAGATGGCCGTGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043474_3

>merge|NZ_CP043474|3|5280139-5280229|CRISPRCasFinder
CTGGCCGTTGGAGATGGCCGTGCCGGTCTGCGAGATCGCGTTGGTTCCCGCGGTGCCCACCTGCTGCTGACCGTTGGAGATGGCGCCGCCG

>NZ_CP043474|3|3|5280139-5280229|CRISPRCasFinder
CTGGCCGTTGGAGATGGCCGTGCCG	GTCTGCGAGATCGCGTTGGTTCCCGCGGTGCCCACCTGCTG
CTGACCGTTGGAGATGGCGCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043474.1\|WP_070355039.1\|5291168_5292074_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070355053.1\|5271189_5272275_-\|threonine-synthase	unknown	unknown	gnl\|CDD\|236013
NZ_CP043474.1\|WP_070355060.1\|5285602_5287312_+\|sodium:solute-symporter-family-protein	unknown	unknown	gnl\|CDD\|271372
NZ_CP043474.1\|WP_170292479.1\|5278587_5279379_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223780
NZ_CP043474.1\|WP_099046020.1\|5289154_5290486_+\|sensor-domain-containing-protein	unknown	unknown	gnl\|CDD\|226951
NZ_CP043474.1\|WP_070355051.1\|5273590_5275015_-\|diaminopimelate-decarboxylase	unknown	unknown	gnl\|CDD\|273415
NZ_CP043474.1\|WP_070355052.1\|5272271_5273594_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NZ_CP043474.1\|WP_070355059.1\|5287683_5288103_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|281995
NZ_CP043474.1\|WP_070355050.1\|5275011_5276661_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP043474.1\|WP_070355975.1\|5265386_5266976_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|237374
NZ_CP043474.1\|WP_125939812.1\|5276886_5278512_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_149484339.1\|5267828_5269964_-\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|237171
NZ_CP043474.1\|WP_070355044.1\|5282498_5283587_-\|galactokinase	unknown	unknown	gnl\|CDD\|179063
NZ_CP043474.1\|WP_170292480.1\|5280619_5280775_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_070355040.1\|5290473_5291118_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP043474.1\|WP_070355058.1\|5288132_5289050_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|366009
NZ_CP043474.1\|WP_083298450.1\|5283583_5285467_-\|galactose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|238341
NZ_CP043474.1\|WP_070355054.1\|5270245_5271181_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP043474.1\|WP_070355041.1\|5287324_5287603_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043474.1\|WP_083298565.1\|5267067_5267748_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP043474.1\|WP_070355053.1\|5271189_5272275_-\|threonine-synthase	gnl\|CDD\|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NZ_CP043474.1\|WP_070355060.1\|5285602_5287312_+\|sodium:solute-symporter-family-protein	gnl\|CDD\|271372	cd11478, SLC5sbd_u2, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	0
NZ_CP043474.1\|WP_170292479.1\|5278587_5279379_-\|hypothetical-protein	gnl\|CDD\|223780	COG0708, XthA, Exonuclease III [DNA replication, recombination, and repair].	1.71183e-28
NZ_CP043474.1\|WP_070355051.1\|5273590_5275015_-\|diaminopimelate-decarboxylase	gnl\|CDD\|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	5.24119e-173
NZ_CP043474.1\|WP_070355052.1\|5272271_5273594_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_CP043474.1\|WP_070355050.1\|5275011_5276661_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP043474.1\|WP_070355975.1\|5265386_5266976_-\|AMP-binding-protein	gnl\|CDD\|237374	PRK13388, PRK13388, acyl-CoA synthetase; Provisional.	0
NZ_CP043474.1\|WP_070355040.1\|5290473_5291118_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.36137e-38
NZ_CP043474.1\|WP_070355054.1\|5270245_5271181_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	8.34718e-100
NZ_CP043474.1\|WP_070355044.1\|5282498_5283587_-\|galactokinase	gnl\|CDD\|179063	PRK00555, PRK00555, galactokinase; Provisional.	4.13481e-176
NZ_CP043474.1\|WP_099046020.1\|5289154_5290486_+\|sensor-domain-containing-protein	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.81301e-36
NZ_CP043474.1\|WP_070355058.1\|5288132_5289050_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	3.8007e-29
NZ_CP043474.1\|WP_083298450.1\|5283583_5285467_-\|galactose-1-phosphate-uridylyltransferase	gnl\|CDD\|238341	cd00608, GalT, Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme contains two identical subunits. It also demonstrates that the active site is formed by amino acid residues from both subunits of the dimer.	1.40498e-119
NZ_CP043474.1\|WP_149484339.1\|5267828_5269964_-\|transcription-termination-factor-Rho	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0
NZ_CP043474.1\|WP_070355059.1\|5287683_5288103_-\|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl\|CDD\|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	5.46977e-47
NZ_CP043474.1\|WP_083298565.1\|5267067_5267748_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.20963e-10

>NZ_CP043474.1|WP_170292479.1|5278587_5279379_-|hypothetical-protein
MTRADGTTRFLTWNIQSGGGNRVPQIMREVDLLAPDVVGFTEVKSNNLATLSRTLEASGFDYIETPSGEDVNSVLLASKKPFEAVKEEITHDQERWASVRIPSMDLRVLCVHIPGSPDHKFDSEGRGMSGQKRKELLWYEVIRYATIHKDERVAIMGDLNTGLNEIDRTPRGTPFKLSENIRVLRMDGRFTDTWRYLNPKNRDYTWFTTRDGRDFNGFRLDYIWVSAPLRESIRSAQHLHHVRGKVSDGKLSDHAIVVADIAL
>NZ_CP043474.1|WP_125939812.1|5276886_5278512_-|hypothetical-protein
MAAAPPTPQAVIEGFLLRTRRVMAHSLIREQAALITKLHKGEVTIMVEVNTKTDEESHRLQAEYPPEEALESLASRVRPLVLSSEPIYYAKMLDALEQVAGTDSLNEEIDLEWWHHYWRAVIDANLGAQAYWAATPSGDTTDRKLMHTWLDGDVIHAQSPRSSVIRDLSLDQRYYDAAPGIARICDRVIYTHLMLTALIEKGLLTVDPAVLSDPVVVTTTTVDEPVSVSVSDVGVPIPDDVTTLGPDALDPAVWRSPHQDLASLRREASTEGGASPVWLVDRAASQQRKAQLESYLAANVWNDSEDFICRTAGACRLSAEKAGASFYEAQSHMVGPCYDTQVDGKPYRVLVLPMETGEAKQHRTVEQRTEDVLTAGKVGFGQRNQHMRGVTFALRLAFGLPVDADIEHISFGDGSRAHFFDAYAMTNLLLCSAVDAGTANSRATGVMRKSCSRHLRATIDILQPSLVISQGARLKDTLFAALGVNGSIAANVNACALNGNSFVWVSLRHPSRGNWSSLKCTYLHEVVVPAIAKGRAAALDG
>NZ_CP043474.1|WP_070355050.1|5275011_5276661_-|arginine--tRNA-ligase
MTPADLALLLKTTAAAVLAERGLDTAALPETVTVERPRNPEHGDYATNLALQVGKKVGTNPRELAGWLAEALTAADGISGADVAGPGFVNLRIETAAQSVVVSNVLAAGDAYGHSDALGIKVNLEFVSANPTGPIHIGGTRWAAVGDALGRLLSTQGAEVVREYYFNDHGAQIDRFARSLVAAAKGQPAPEDGYAGGYIVDIANQVLAQAPDVLGLPDDAQQETFRSIGVDLMFAHIKSSLHEFGTDFDVYTHEDSMHTSGRVEQAIAKLRETGNIYEKDGATWLRTTEFGDDKDRVVIKSDGNPAYIAGDLAYYLDKRQRGFDLCIYMLGADHHGYIARLKAAAAALGDDPNTVEVLIGQLVNLVRDGQPVRMSKRAGTVITLDDLVDAIGVDAARYVLIRSSVDSPIDIDLELWSSASSENPVYYVQYAHARLSALARSAADLGIAADTGHLDLLTHDREGTLMRTLGEFPRILATAVALREPHRVCRYLEDLAGDYHRFYDSCRVLPMGDEEPGDLHAARLALCAATRQVIANGLDILGVSAPERM
>NZ_CP043474.1|WP_070355051.1|5273590_5275015_-|diaminopimelate-decarboxylase
MMAHPAGPRHAEAKRHPGTPPRPASPDEILLIAPNVWPRNAARGDGGELSIAGVPVSRLAADYGTPLFVIDEDDFRTRCRDIAMAFGGGEHVRYAAKAFLCSEIARWIHQEGLALDVCSGGELAVALHAGFPAERIALHGNNKSVAELTRAVEVGVGHVVVDSEIEIERLDAIAGAAGVVQNVLLRVTVGVEAHTHEFISTAHEDQKFGLSLASGAAMNAVRRVFATDNLRLVGLHSHIGSQIFDVAGFELAAHRVIGLLRDVVAEFGVEKTAQMSIVDLGGGLGISYLPHDDPPPMKELADTLWAIVRSESAAVGLPTPTLVVEPGRAIAGPGTITLYEVGTVKDVAISAGASRRYVSVDGGMSDNIRTSLYDAEYDARLVSRTSDAPPALARIVGKHCESGDIVVRDTWVSDDVTPGDLIGVAATGAYCYSMSSRYNLLARPAVVAVRDGVSRLILRRETVDDLLSLEVENP
>NZ_CP043474.1|WP_070355052.1|5272271_5273594_-|homoserine-dehydrogenase
MTDPKPIGVAVLGLGNVGSEVVRIIGDSAADLAARIGAPLELRGVGVRRVADDRGVPADLLTDDVEALAARDDVDIVVELMGPVEPARKAILTALEHGKSVVTANKALMAQSTGELAQAAESARVDLYFEAAVAGAIPVIRPLTQSLAGDSVLRVAGIVNGTTNYILSAMNDTGADYASALADASALGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKVTAEDFASAKALGCNIKLLAICERLTNDEGQQRVSARVYPALVPSDHPLASVGGAFNAVVVEAEAAGRLMFYGQGAGGAPTASAVMGDLVMAARNRVQGGLGPRESKYAQLPISPIGFIPTRYYVSMNVADRPGVLSSVAAEFGKREVSIAEVRQEGMVDEGGQPCGARIVVVTHRATDAALSETVAALADLDVVQTINSVLRLEGTTE
>NZ_CP043474.1|WP_070355053.1|5271189_5272275_-|threonine-synthase
MTNTHARAVHQPWPGLINAYRDRLPIGEGWTPITLLEGGTPLIHAARISEMTGCTVHLKVEGLNPTGSFKDRGMTMAVTESVARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGRIAMGKLAQAVMHGAKIIQVDGNFDDCLELARKLTADFPTIALVNSVNPYRIEGQKTAAFEIVDALGTAPDVHALPVGNAGNITAYWKGYTEYHRDGLSDRLPRMLGTQAAGAAPLVSGEPVKNPDTIATAIRIGAPASWNSAVEAQQQSNGKFLAATDEEILAAYHLVARTEGVFVEPASAASIAGLLKSVEDGWVAKGSTVVCTVTGNGLKDPDTALKGMPEVEAVPVDPVAVVAQLGLV
>NZ_CP043474.1|WP_070355054.1|5270245_5271181_-|homoserine-kinase
MTQTLPAGLSASAVVAASSANLGPGFDSLGLALGLYDEIDVETTDSGLVIDVTGEGAGQVPLDASHLVVRALRRGLDAAGVTVGGLKISCRNVIPHSRGLGSSAAAVVGGLAAANGLIAQSDSPVLDDGDLIQLSSEFEGHPDNASAAVLGGAVVSWTEADGATPRYRAAPLRLHPDIRLFPAVPAVRSSTAETRAVLPEEISHVDARFNVSRVALLVVALTERPDLLAAATEDRLHQPQRASAMPASAEYIAILRRCGVATVLSGAGPAVIAITTESELPAEALEFGAAHGFAITEMAQGDGVRWTPGPR
>NZ_CP043474.1|WP_149484339.1|5267828_5269964_-|transcription-termination-factor-Rho
MTDTDLITAGGSSDDVAVPESVDSPSAAPAAEAPSAQRAVPLTAMVLPDLRALASSLGVKTTGMRKGDLIAAIREQRGDTNGAAAPANGQADAPAAEQAPAADQAATEQAPRRRERRGASRQTGAPARADGDTADAPTADATAAPAEADGREQAPATSDRPKADRAETTDGAAEKTDRAVEADAGDGRTPQKDGGQNKGDQGGRNGSGGNGRNERGNNERNDRGNNERGNNERGNNERGNNERNDRGNNERGNNERNDRGNNERNDRGNNERNERGNSDRNDRNNATDDDDDEGRGGRRGRRFRDRRRRERGGNEGGGNDTELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNMVRKNGLRRGDAVTGAVRVAREGEGGGGNNPRQKFNPLVRLDSVNGGSVEDAKKRPEFGKLTPLYPNQRLRLETSGDKLTTRVIDLIMPIGKGQRALIVSPPKAGKTTIMQDIANAITQNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTQAAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEHGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLSPDEFAIVHKLRRVMSGLDPHQAIDLLMSQLRKTKNNYEFLVQVSKNTPGGTGDD
>NZ_CP043474.1|WP_083298565.1|5267067_5267748_+|TetR/AcrR-family-transcriptional-regulator
MHPSASPRGTFAQPEEAPLTTTPAPPESAPQSRSVRDRLIDAAEECLRVKGIRSTTVSEVAEVAGVSRGWLYRHFPDKVTLLGAALVRLNDAYWSESHALLDEVQGLAEQIAAGISHARTAYDDPGALLMKLRMAEPEEFAACAGAGVQGLVPDLAAFWRRYVVAARDAGEIHPDVHVDEAAEWVARAILSLTTVPGAQLDAADPAAVLVHVKRYVMPGLRTDPAV
>NZ_CP043474.1|WP_070355975.1|5265386_5266976_-|AMP-binding-protein
MPDTLQQLLRERADVDTPAVRFGDRTWTWRQHIAEAFAQAAALIDAADAERPLHVGVLLGNTPDMLTALAAAALGGYVLCGINTTRRGEAIARDVARVDCQILLTDAEHRHLLDGIDLPGVSVFDVSAPEWSQRTAAAPGLVPHAEVGADDTFMMIFTSGTSGEPKAVEVPHAMVLFAGTALVERYALDASDVCYLAMPLFHSNAVYAGWSVALNAGATMAPASFSASRFLDDVRRYGVTYMNYVGKPLAYILATAERPDDADNPLRIAFGNEAADRDIDEFGRRFGCTVWDGFGSTETAVIITRPDDCPTGSIGKGFPGVAIFDPETVTECEVARFDASGALLNAAAATGELVNTSGSGLFRGYYNDQGATDQRMRHGMYWSGDLAYRDADGWIYLAGRTADWMRVDGENLTTAPIERILLRLNAISRVAVYPVPDEYVGDQVMAALVLRDGAALTPAEFGAFLAAQPDLSPKAWPRYVWIAEDLPSTATNKILKRDLVAMGTDPAGRTLWTREGRTFGVLAVTGTDR
>NZ_CP043474.1|WP_170292480.1|5280619_5280775_-|hypothetical-protein
MATRVGALAIQNSVQDADDHAGIGLGVHGGSMHVATADPVDHGSPRRKLAV
>NZ_CP043474.1|WP_070355044.1|5282498_5283587_-|galactokinase
MTVRFEAPGRINLIGEHTDYNLGYALPIALPERTTVTFDPDDSDALRVGSAGEPDGVTVPLDTGTGDVAGWGAYVAGVVWALRQAGHPVRGGRMRIDSDVTMGSGLASSAALECAVLGALLAASGTELDRTEQARIARHAENDYVGAPTGLMDQLASLHGAARQALLIDFRSLDVQPVGFDPDAVGMALLLIDSRAPHRHAGGEYAARRRSCERAAAALGVTSLREAQDVGLERLGELDPTDARRARHILTENARVLDVVVALEAGDLKTVGEIFTASHASMRDDFEITTPQIDMIAQTAVDAGALGARMTGGGFGGCVIALVPEDALRAVSTAVPGALRAAGFNEPTLVRTSAAAGAGPVA
>NZ_CP043474.1|WP_083298450.1|5283583_5285467_-|galactose-1-phosphate-uridylyltransferase
MHARRRASPRHPGEPAVRGCRAGGRPRRRALGLRDDRPARPRRARRAGVAQQGARGCGHPAPSRRRAEIGGEGAAATRREGGDRPGRRRARRRRHDDRHRGGQHHHRTRAAAARPPVGHRDHQLAARVRRPHRARRRITRARRVSVGRHAHPVGRARRPHRRHRPRVVPGGRHVPRRARRRRARWADVAERRRGTDQPDAHRDLGPAGGPGRPHQVRRGRRVRVRASRPGARADRRRWTERRRTVGARRTRRRTDRGDPRGALVTEPLAWTLADGRDELFFALPGHRPAPVPDRRPLPPRSAQRSEIRFDRQTGQWVVIAALRQDRTYKPPPDQCPLCPGPSGLSSEIPAPDYDVVVFENRFPSLSGAGVEPFDLPDPDRDVFTAAPGHGRCEVICFSSDHRASFAQLPHDRARLVVHAWRHRTADMMQRNGIRQVFCFENRGEEIGVTLTHPHGQIYGYPYVTPRSALVLREARAYRRRHDANLFGAILDREVADGARIIARTDAFTAFVPFAARWPVEVHVYPNRRVHNLLDLTDAEIDAFAAVYLDVLRRFDRLYPTPLPYISALHQYRDDDEQGEGWFHVELMSVRRSATKLKFLAGSESAMDAFISDVTPESVAARLREVGT
>NZ_CP043474.1|WP_070355060.1|5285602_5287312_+|sodium:solute-symporter-family-protein
MTTTLAADSVLRLHVGVLDYLLIAIYFVFVLGIGYLARSQISTSLDFFLSGRRLPAWVTGLAFVSANLGAVEIMGMSANGAQIGLATMHYYWIGAVPAMIFLGIVMMPFYYGSKVRSVPEFMRKRFGPGAHLVNAISFAVAQVLIAGVNLFLLATVINVLLDWNRWISLIVAALIVLTYTALGGLSAAIYNEVLQFFVILAALVPLTIFGLIKVGGWSGLRDKVIDTVNADAAVTASAHEQLTSWPGQALSGFDSPLWSVIGIVFGLGFVLSFGYWTTNFVEVQRAMASDSISAARRAPIIAAFPKMFIPFVVVVPGMIAAAAIGDLINLKSTGSGDITYNDAMLLMIRDILPNGLIGVAVAGLIASFMAGMAANVSAFNTVFSYDIWQQYVVKDRSDAYYIQVGRVATLGATVLAVFTALIAAGYSNLMDYLQTLFGFFNAPLFATFILGMFWKRMTATAGWAGLVAGTLSAVTVFVLSEVGVIDLPGQGMPFLAAAAAFIVDIAVSVVVSYATTPKPVAALAGFVYSETPVQIFADPESDGKAWYLRPVPLAGVMLALAVVLNIVFH
>NZ_CP043474.1|WP_070355041.1|5287324_5287603_+|hypothetical-protein
MSAPKAVSRIFDIRNIIGALLGIYGVLLTLAGLVPSLVAHHDDEAAANNTVDLYVGTDANWWVGVALLAVAATFIAWAALRPVVAAPPSATE
>NZ_CP043474.1|WP_070355059.1|5287683_5288103_-|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MSEAELSPTDWVREQTERILAQGTTDGVEVLDRPIVLFTTTGAQSGKKRYVPLMRVEENGKYAMVASKGGDPKHPSWYFNVKANSAVTVQDGEKVLEGTAREISGEEREHWWKLAVEAYPPYAEYQTKTDRQIPVFVVE
>NZ_CP043474.1|WP_070355058.1|5288132_5289050_-|LLM-class-flavin-dependent-oxidoreductase
MTMPVMEPNLDAATLKAWARLVDGGPFSSLCWGERICFDNPESLTLLGALSAWTDRVRLVTTVIVPQLHDPVLLAKSLATGDLLSGGRLTVGLGVGGRHEDYASVGADTATQTMRGMAERVAVMKRVWAGEKVADSVLPVGPRPVQSPGPRLVVGTIGPKTIRSAAAWADGVAGTTLDLNVDREAELFDVARTAWAEAGKPAPRLATSFWFAMGPRDAARAQVHRHLRRYMNWIPEEFVDAMAPTTGWAGDEEDLLAVLRRFEDIGADEVHLIPTSVDIDQVRRVADVAAQFTGRDTPHDTPVRE
>NZ_CP043474.1|WP_099046020.1|5289154_5290486_+|sensor-domain-containing-protein
MVDVMTPSEPLDAPVAGPAPATAAEGPAPVRRIGLVPTASMVSGAALGIVWFWIPLGLLIGGVSAIPSVVGFALAVVVFVYLVRGIDRVERVRSEAVFGMGIGVPPRKQSPYTGFQGWAHQLWLDLGSARFWKAFGHHYLRLAYDILATGVALALVVFAFAAPAVATAIDASDDAAGLAFVSPPLAWLLAVVAVAAAVAILVVAPALDARIDRWLLPPSATAALQHEVTALTDAREGAVSSAHTERSRIERDLHDGVQPRLVSLAMTIGLARTKLDSDPAEARTLIEEAHDSAKSALAELRNVVRGIAPTILSDRGLDAALSAVVQRTQSAGVPTTLDVHLPRRLPEEVEACAYFVVAEALTNVVKHARAGQAIVTVRLDESADTLHVSVFDDGVGGAEAPAGENTTGLRGLGDRVRAARGTFTVTSPATGPTIVTAVLPCAS
>NZ_CP043474.1|WP_070355040.1|5290473_5291118_+|response-regulator-transcription-factor
MRIVIAEDSALLRAGIERILGDAGHDVVAGVADATDLLRIVNELRPDLAILDVRMPPTFTDEGIRAAALLRSQNPESPVLVLSHYVEERYAADLIASDTRGFGYLLKDRVADVPAFLDAVTVVGGGGTVLDPEVVSQILVRSRQRSALDALSPRETEVLQLMAEGRTNSAIAAALHVSVGSAEKHIASIFTKLGLAPDESENRRVLAVLRYLES
>NZ_CP043474.1|WP_070355039.1|5291168_5292074_+|hypothetical-protein
MNRPRGNPVVTTIAPPPLSPGGRTAFRVFLVVVATVAVVGTVVALGATAWGVSTFRVVADEKTLPAGTRTLTIDTGDVPAAVRLRTDRDAVEPRITMRLLDTARSGEQALDVRTSGSDTRVVVAGARADVLGWGRAGEITVSLPPETSRRLAVTTRQGTGVLFAGADLDSLTATNADGAVVLGGSARRLEVRTQDADVVTREPVAVAESFVADTVNGDVTVDFADAAPATIEAATETGDVALGLPDPGPYLVRASGTSTRVRVSETEDAGRAAARVTVRAGDGSAVVDRSGAPRLARHDRP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP013744	Streptomyces sp. CdTB01 plasmid unnamed, complete sequence	3505-3534	5	0.833
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	87455-87484	5	0.833
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	496595-496624	6	0.8
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	99151-99180	6	0.8
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2822832-2822861	6	0.8
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	54488-54517	6	0.8
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NC_009475	Bradyrhizobium sp. BTAi1 plasmid pBBta01, complete sequence	56397-56426	7	0.767
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1080926-1080955	7	0.767
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	910163-910192	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1023334-1023363	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	36851-36880	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	789794-789823	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	651498-651527	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	218015-218044	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	280419-280448	8	0.733
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	609398-609427	9	0.7
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	510479-510508	9	0.7
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	510469-510498	9	0.7
NZ_CP043474_1	1.1\|1233888\|30\|NZ_CP043474\|CRISPRCasFinder	1233888-1233917	30	MT701587	Burkholderia phage Magia, complete genome	15350-15379	9	0.7

1. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP013744 (Streptomyces sp. CdTB01 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
catgccgctcgcgggcggctcggtgccgtc	Protospacer
  ** .******** ***************

2. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 5, identity: 0.833

gctggtgctcgcggccggctcggtgccgtc--	CRISPR spacer
gctggtgatcgcgaccggctcggt--cgacaa	Protospacer
******* *****.**********  ** *

3. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 6, identity: 0.8

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gctgctgctcgcggccggctcggcccggcg	Protospacer
**** ******************. * *.

4. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 6, identity: 0.8

gctggtgct---cgcggccggctcggtgccgtc	CRISPR spacer
---ggcgcctggcgcggccggctcgatgccgtc	Protospacer
   **.**.   *************.*******

5. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

gctggtgctcgcggccggct-cggtgccgtc	CRISPR spacer
gctggtgctcgcgggcggctccaacgtcgt-	Protospacer
************** ***** *...*.***

6. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 6, identity: 0.8

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
ggaggggctcgcggccggttcggtgcggcc	Protospacer
*  ** ************.******* *.*

7. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NC_009475 (Bradyrhizobium sp. BTAi1 plasmid pBBta01, complete sequence) position: , mismatch: 7, identity: 0.767

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gctggtgctcgcggtcggctcccatcgatc	Protospacer
**************.******    * .**

8. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gctggtgcgcgaggccggctcgggctcgcg	Protospacer
******** ** ***********  .**.

9. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gctcgtgctcgtggccggctcggccctcat	Protospacer
*** *******.***********. *.  .

10. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gctggtgctccaggccggctcggacgggcg	Protospacer
**********  ***********    *.

11. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
atcggtgctcgcggccggcacggagcggca	Protospacer
...**************** *** ** *.

12. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gctggtgctccaggccggctcggacgggcg	Protospacer
**********  ***********    *.

13. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
ggcggtgctcgcggccgagtcggtgcgcga	Protospacer
* .**************. *******

14. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
ggaggtgctcgcggcctggtcggtgctcgt	Protospacer
*  ************* * *******.  .

15. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
gacgagatgcgcggccgggtcggtgccgtc	Protospacer
* .*. .. ********* ***********

16. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.7

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
tgtggcggtcgcggccggctcggtggacaa	Protospacer
  ***.* *****************

17. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
tgtggcggtcgcggccggctcggtggacaa	Protospacer
  ***.* *****************

18. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
tgtggcggtcgcggccggctcggtggacaa	Protospacer
  ***.* *****************

19. spacer 1.1|1233888|30|NZ_CP043474|CRISPRCasFinder matches to MT701587 (Burkholderia phage Magia, complete genome) position: , mismatch: 9, identity: 0.7

gctggtgctcgcggccggctcggtgccgtc	CRISPR spacer
cacgaccctcgcggccggctcggtggcgag	Protospacer
  .*.. ****************** **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

190996 : 244899

Corynebacterium_phage(50.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_070356446.1\|190996_192232_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7
WP_083298647.1\|193527_193872_-	Lsr2 family protein	A0A160DEV0	Gordonia_phage	1.2e-19	49.1
WP_170292377.1\|194968_195562_+	PAS domain S-box protein	NA	NA	NA	NA
WP_070356446.1\|195580_196816_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7
WP_070356415.1\|196938_197349_+	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_083298640.1\|197246_197573_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_125939894.1\|198544_199585_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_070356413.1\|200107_200428_+	hypothetical protein	NA	NA	NA	NA
WP_070356412.1\|200424_201198_+	SigB/SigF/SigG family RNA polymerase sigma factor	A0A0Y0AU18	Bacillus_phage	6.8e-23	32.6
WP_083298592.1\|201722_202385_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_083298593.1\|202440_203322_-	NmrA family NAD(P)-binding protein	NA	NA	NA	NA
WP_125939851.1\|204880_205162_+	hypothetical protein	NA	NA	NA	NA
WP_170292378.1\|205342_206509_+	EAL domain-containing protein	NA	NA	NA	NA
WP_070356172.1\|206686_206905_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_125939852.1\|207380_209165_+	hypothetical protein	NA	NA	NA	NA
WP_125939853.1\|209145_209670_-	NUDIX domain-containing protein	A0A249Y765	Cherax_quadricarinatus_iridovirus	4.4e-05	34.2
WP_070356173.1\|209756_209975_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_070356174.1\|210103_211243_-	hypothetical protein	NA	NA	NA	NA
WP_083298597.1\|211293_211830_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_125939854.1\|211937_212549_-	hypothetical protein	NA	NA	NA	NA
WP_125939855.1\|212763_213330_-	hypothetical protein	NA	NA	NA	NA
WP_083298596.1\|214046_214694_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_070356297.1\|218296_218692_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_125939876.1\|219002_219527_+	hypothetical protein	NA	NA	NA	NA
WP_125939877.1\|220139_220679_+	hypothetical protein	NA	NA	NA	NA
WP_149484170.1\|220697_221312_-	hypothetical protein	NA	NA	NA	NA
WP_070356298.1\|221982_222204_-	hypothetical protein	NA	NA	NA	NA
WP_070356299.1\|222323_223061_-	GAF and ANTAR domain-containing protein	NA	NA	NA	NA
WP_125939879.1\|224303_224921_+	hypothetical protein	NA	NA	NA	NA
WP_125939880.1\|225160_225523_-	hypothetical protein	NA	NA	NA	NA
WP_070356446.1\|225831_227067_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7
WP_099046100.1\|227327_227978_-	DUF3761 domain-containing protein	NA	NA	NA	NA
WP_083298618.1\|228418_228616_-	excalibur calcium-binding domain-containing protein	NA	NA	NA	NA
WP_125939870.1\|230087_230465_-	hypothetical protein	NA	NA	NA	NA
WP_125939871.1\|230464_231877_-	hypothetical protein	NA	NA	NA	NA
WP_125939872.1\|232064_232481_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_070356284.1\|232861_233092_+	hypothetical protein	NA	NA	NA	NA
WP_070356285.1\|233271_233871_-	PASTA domain-containing protein	NA	NA	NA	NA
WP_125939873.1\|234579_235959_-	hypothetical protein	NA	NA	NA	NA
WP_125939874.1\|236183_236903_-	hypothetical protein	NA	NA	NA	NA
WP_070356446.1\|237136_238372_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7
WP_070356453.1\|238988_239960_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_125939725.1\|240114_240438_-	hypothetical protein	NA	NA	NA	NA
WP_125939724.1\|241568_242054_-	hypothetical protein	NA	NA	NA	NA
WP_125939723.1\|242322_242649_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_083298255.1\|242899_243415_+	SLATT domain-containing protein	NA	NA	NA	NA
WP_095762103.1\|243761_244899_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	8.2e-33	34.8

DBSCAN-SWA_2

704749 : 731088

Corynebacterium_phage(60.0%)

transposase,holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099045896.1\|704749_705484_-\|protease	serine protease	NA	NA	NA	NA
WP_070353048.1\|705612_706122_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_070353049.1\|706121_707135_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_070353050.1\|707131_708319_-\|protease	acid resistance serine protease MarP	NA	NA	NA	NA
WP_070353051.1\|708315_709098_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_070353052.1\|709094_709742_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_170292488.1\|709738_710425_-	endonuclease III	NA	NA	NA	NA
WP_070353077.1\|710611_710965_+	hypothetical protein	NA	NA	NA	NA
WP_149484184.1\|711063_711738_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_083298211.1\|711786_712689_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_070353055.1\|712597_713074_-	RidA family protein	M1I5B0	Acanthocystis_turfacea_Chlorella_virus	4.5e-17	37.4
WP_099045897.1\|713070_713232_-	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_070353056.1\|713280_714321_+	ArsA family ATPase	NA	NA	NA	NA
WP_070353078.1\|714320_715445_+	ArsA family ATPase	NA	NA	NA	NA
WP_070353057.1\|715458_715815_-	WhiB family transcriptional regulator	A0A0K1Y796	Mycobacterium_phage	2.6e-09	45.9
WP_070353058.1\|716153_718610_+	transglycosylase/D,D-transpeptidase PonA2	NA	NA	NA	NA
WP_070353079.1\|718777_719746_+	metallophosphoesterase	NA	NA	NA	NA
WP_170292489.1\|719808_720849_+	PLP-dependent cysteine synthase family protein	NA	NA	NA	NA
WP_083298213.1\|720749_720968_-	hypothetical protein	NA	NA	NA	NA
WP_149484185.1\|721934_722576_-	hypothetical protein	NA	NA	NA	NA
WP_070356446.1\|722698_723934_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7
WP_070356446.1\|726275_727511_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7
WP_070356446.1\|729852_731088_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	5.5e-83	43.7

DBSCAN-SWA_3

2333015 : 2340440

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_070351349.1\|2333015_2334011_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.9e-71	45.0
WP_070351378.1\|2334013_2334883_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	1.2e-92	58.8
WP_070351350.1\|2335077_2335971_-	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	2.8e-20	26.6
WP_070351351.1\|2336142_2337021_-	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.6e-31	31.2
WP_070351352.1\|2337140_2338019_-	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	1.5e-29	31.2
WP_070351353.1\|2338141_2339047_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_070351354.1\|2339054_2340440_-	AarF/ABC1/UbiB kinase family protein	G8DDN0	Micromonas_pusilla_virus	2.2e-32	31.1

DBSCAN-SWA_4

3189095 : 3196860

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_070353410.1\|3189095_3189992_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	4.0e-06	28.5
WP_070353409.1\|3189988_3191140_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	1.1e-56	36.6
WP_070353408.1\|3191151_3192225_-	DNA polymerase IV	A0A2H4JBL5	uncultured_Caudovirales_phage	7.1e-10	26.8
WP_070353407.1\|3192221_3192839_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_070353406.1\|3192928_3193471_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	5.7e-08	34.5
WP_070353405.1\|3193964_3194207_+	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	9.9e-21	63.6
WP_070353404.1\|3194278_3194725_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_083298240.1\|3194691_3196860_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	8.7e-209	51.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP043474

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection