CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP039448	Staphylococcus aureus strain VGC1 chromosome, complete genome	12 crisprs	cas3,DEDDh,DinG,csa3,WYL	4	3	13	1
NZ_CP039450	Staphylococcus aureus strain VGC1 plasmid pVGC1_2, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP039449	Staphylococcus aureus strain VGC1 plasmid pVGC1_1, complete sequence	0 crisprs	csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP039448_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_1

650608-650715

Orphan

Consensus_repeat	Method
CAACTGCATAAGAGCCCCTAATCGCTAAAGCTCAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_1

>merge|NZ_CP039448|1|650608-650715|CRISPRCasFinder
CAACTGCATAAGAGCCCCTAATCGCTAAAGCTCAAGGGGGTTAAAGAATACAGTTGGTTTGCTTGCGCACAACTGCATAAGAGCCCCTAATCGCTAAAGCTCAAGGGG

>NZ_CP039448|1|1|650608-650715|CRISPRCasFinder
CAACTGCATAAGAGCCCCTAATCGCTAAAGCTCAAGGGG	GTTAAAGAATACAGTTGGTTTGCTTGCGCA
CAACTGCATAAGAGCCCCTAATCGCTAAAGCTCAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_001200748.1\|647109_648120_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP039448.1\|WP_001018677.1\|657955_658330_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP039448.1\|WP_000180234.1\|644766_646062_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP039448.1\|WP_001045420.1\|656914_657703_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP039448.1\|WP_001824079.1\|659277_660207_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP039448.1\|WP_001788287.1\|646089_646611_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP039448.1\|WP_000365354.1\|653722_654442_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP039448.1\|WP_000735555.1\|655361_655868_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001222132.1\|656029_656746_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000633786.1\|643544_644081_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP039448.1\|WP_001021155.1\|648807_650469_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP039448.1\|WP_031845074.1\|641366_641483_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000808897.1\|642396_643335_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP039448.1\|WP_001819741.1\|648427_648811_+\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP039448.1\|WP_000901752.1\|650734_651370_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP039448.1\|WP_000143689.1\|652717_653668_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP039448.1\|WP_072358141.1\|651739_652567_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP039448.1\|WP_000477504.1\|644250_644727_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP039448.1\|WP_000362965.1\|654425_655226_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP039448.1\|WP_000882152.1\|640680_641310_+\|DUF443-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_001200748.1\|647109_648120_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP039448.1\|WP_001824079.1\|659277_660207_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	2.23747e-34
NZ_CP039448.1\|WP_000180234.1\|644766_646062_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.30042e-150
NZ_CP039448.1\|WP_001045420.1\|656914_657703_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.46764e-34
NZ_CP039448.1\|WP_001788287.1\|646089_646611_+\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP039448.1\|WP_000365354.1\|653722_654442_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP039448.1\|WP_001018677.1\|657955_658330_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_CP039448.1\|WP_000633786.1\|643544_644081_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	2.68466e-26
NZ_CP039448.1\|WP_001021155.1\|648807_650469_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP039448.1\|WP_000901752.1\|650734_651370_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.48192e-91
NZ_CP039448.1\|WP_000808897.1\|642396_643335_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.79608e-168
NZ_CP039448.1\|WP_001819741.1\|648427_648811_+\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
NZ_CP039448.1\|WP_000143689.1\|652717_653668_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	8.77759e-48
NZ_CP039448.1\|WP_072358141.1\|651739_652567_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.35372e-72
NZ_CP039448.1\|WP_000477504.1\|644250_644727_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP039448.1\|WP_000362965.1\|654425_655226_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	9.99453e-26
NZ_CP039448.1\|WP_000882152.1\|640680_641310_+\|DUF443-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	1.30052e-64

>NZ_CP039448.1|WP_001021155.1|648807_650469_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGGQFGYVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAATNDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP039448.1|WP_001819741.1|648427_648811_+|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP039448.1|WP_001200748.1|647109_648120_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP039448.1|WP_001788287.1|646089_646611_+|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP039448.1|WP_000180234.1|644766_646062_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVSPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP039448.1|WP_000477504.1|644250_644727_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP039448.1|WP_000633786.1|643544_644081_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTTETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP039448.1|WP_000808897.1|642396_643335_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESLAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVIENIKAADIVLSDDEIQYIDELFPIED
>NZ_CP039448.1|WP_031845074.1|641366_641483_+|hypothetical-protein
MILNRGAILEQGNKKAKVIKSELITNYIMLATLQIKNN
>NZ_CP039448.1|WP_000882152.1|640680_641310_+|DUF443-domain-containing-protein
MLCESRVINQNPKYRIIKYNNEYFMVDLVSTWIAYFLPMINWFIPKKYAKISRKEFESLNIVKPAKNNTFWPVAGFAVLLTTLTRKYIYLLNIHLEKEIVILTCCMILLGVFALFIYINTKLKLHIFDKNKSNNEKIILIPTFKNICLSFFAYIFFGGLSTMALSMLVTSSPQNIIEFLALIGMTACFFLLNMSSVLDKNIHVILKTNK
>NZ_CP039448.1|WP_000901752.1|650734_651370_+|endonuclease-III-domain-containing-protein
MLGTDELYKLLYRHMGPQNWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNANHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKAELRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKSYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP039448.1|WP_072358141.1|651739_652567_+|ABC-transporter-substrate-binding-protein
MKDNDKQGSDDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP039448.1|WP_000143689.1|652717_653668_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLSTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPCKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIGGQIMVVADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP039448.1|WP_000365354.1|653722_654442_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP039448.1|WP_000362965.1|654425_655226_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNVDFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP039448.1|WP_000735555.1|655361_655868_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLANTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP039448.1|WP_001222132.1|656029_656746_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVILVIYFTIRLSSRTRL
>NZ_CP039448.1|WP_001045420.1|656914_657703_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFLSYYLNFLKSVS
>NZ_CP039448.1|WP_001018677.1|657955_658330_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP039448.1|WP_001824079.1|659277_660207_-|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIVLNIFINPDVFSLHFFSNQTFDYTWFVGGLLGVGYLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIIGIVIMNQFNKNNLLLTDQRYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSITLLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP039448_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_2

767361-767446

Orphan

Consensus_repeat	Method
CAATGCGAGTTGGGGTGGGGCCCCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_2

>merge|NZ_CP039448|2|767361-767446|CRISPRCasFinder
CAATGCGAGTTGGGGTGGGGCCCCAACACAGAGAAATTGGAACGCCAATTTCTACAGGCAATGCGAGTTGGGGTGGGCCCCAACAT

>NZ_CP039448|2|2|767361-767446|CRISPRCasFinder
CAATGCGAGTTGGGGTGGGGCCCCAACA	CAGAGAAATTGGAACGCCAATTTCTACAGG
CAATGCGAGTTGGGGTGGGCCCCAACAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000193751.1\|769068_770574_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP039448.1\|WP_000022323.1\|755201_756206_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_CP039448.1\|WP_000562498.1\|775684_776656_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_CP039448.1\|WP_001790091.1\|772684_772951_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000525113.1\|758890_760774_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP039448.1\|WP_000197262.1\|766729_767272_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_CP039448.1\|WP_000983680.1\|760785_762567_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NZ_CP039448.1\|WP_071665613.1\|770635_770884_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000429011.1\|767879_768797_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_CP039448.1\|WP_000663039.1\|765512_766571_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NZ_CP039448.1\|WP_000855509.1\|773461_775567_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_CP039448.1\|WP_000930014.1\|770913_771414_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_CP039448.1\|WP_000589262.1\|762788_763766_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_CP039448.1\|WP_000180997.1\|763758_765273_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_CP039448.1\|WP_014363392.1\|754204_754411_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000098285.1\|756679_758620_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NZ_CP039448.1\|WP_000708692.1\|754507_755218_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NZ_CP039448.1\|WP_031760357.1\|768889_768991_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000692521.1\|773100_773499_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_CP039448.1\|WP_001068497.1\|771433_772300_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000022323.1\|755201_756206_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NZ_CP039448.1\|WP_000562498.1\|775684_776656_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_CP039448.1\|WP_000525113.1\|758890_760774_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_CP039448.1\|WP_000197262.1\|766729_767272_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
NZ_CP039448.1\|WP_000983680.1\|760785_762567_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP039448.1\|WP_000429011.1\|767879_768797_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	1.47588e-77
NZ_CP039448.1\|WP_000663039.1\|765512_766571_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NZ_CP039448.1\|WP_000855509.1\|773461_775567_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_CP039448.1\|WP_000930014.1\|770913_771414_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NZ_CP039448.1\|WP_000193751.1\|769068_770574_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NZ_CP039448.1\|WP_000180997.1\|763758_765273_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.75128e-152
NZ_CP039448.1\|WP_000098285.1\|756679_758620_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_CP039448.1\|WP_000589262.1\|762788_763766_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	3.31335e-155
NZ_CP039448.1\|WP_000708692.1\|754507_755218_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.29969e-94
NZ_CP039448.1\|WP_000692521.1\|773100_773499_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_CP039448.1\|WP_001068497.1\|771433_772300_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.8323e-10

>NZ_CP039448.1|WP_000197262.1|766729_767272_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NZ_CP039448.1|WP_000663039.1|765512_766571_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISSHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEHFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_CP039448.1|WP_000180997.1|763758_765273_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRLMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_CP039448.1|WP_000589262.1|762788_763766_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTTMSAYPIVYDNQQIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NZ_CP039448.1|WP_000983680.1|760785_762567_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFVLDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NZ_CP039448.1|WP_000525113.1|758890_760774_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMMDAQEAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNVLSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NZ_CP039448.1|WP_000098285.1|756679_758620_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NZ_CP039448.1|WP_000022323.1|755201_756206_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NZ_CP039448.1|WP_000708692.1|754507_755218_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NZ_CP039448.1|WP_014363392.1|754204_754411_+|hypothetical-protein
MIIVYIALLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NZ_CP039448.1|WP_000429011.1|767879_768797_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILSANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_CP039448.1|WP_031760357.1|768889_768991_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS
>NZ_CP039448.1|WP_000193751.1|769068_770574_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_CP039448.1|WP_071665613.1|770635_770884_-|hypothetical-protein
MIFLTYWCVFHLAYIIGYIKITFYTKVHQKNISTRIKQHFYRNLLHFNVNKYIFILSLINCARLIAEYSQYFYFFVICGIFS
>NZ_CP039448.1|WP_000930014.1|770913_771414_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_CP039448.1|WP_001068497.1|771433_772300_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NZ_CP039448.1|WP_001790091.1|772684_772951_+|hypothetical-protein
MCLMYNETHNIVLVKRKRHNILCFVCKCFIYEEITFKSNLTQKFNSYYQLIVIFLENVLSKWKISNDVNTTYSDFYTFNPYKLLFSQI
>NZ_CP039448.1|WP_000692521.1|773100_773499_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_CP039448.1|WP_000855509.1|773461_775567_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYSVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_CP039448.1|WP_000562498.1|775684_776656_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK

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Crispr_ID: NZ_CP039448_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_3

987128-987285

Orphan

Consensus_repeat	Method
CCAACTTGCATTGCTTGTAGAATCTCTTTTCGAAATTCT	PILER-CR
TCTTTTCGAAATTCTCTGTGTTGGGGCCC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP039448_3

>merge|NZ_CP039448|3|987128-987285|PILER-CR,CRISPRCasFinder
AACTTGTATTGCTTGTAGAAATTGGAAATCCAATTGGGGCTCCGCGTCCAACTTGCATTGCTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACTCCCCAACTCGCATTGCTTGTAGAATCTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>NZ_CP039448|3|1|987128-987272|PILER-CR
AACTTGTATTGCTTGTAGAAATTGGAAATCCAATTGGGGC	TCCGCGTCCAACTTGCATTGCTTGTAG
AATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACTCCCC	AACTCGCATTGCTTGTAGA
ATCTCTTTTCGAAATTCTC

>NZ_CP039448|3|3|987199-987285|CRISPRCasFinder
TCTTTTCGAAATTCTCTGTGTTGGGGCCC	ACTCCCCAACTCGCATTGCTTGTAGAATC
TCTTTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_001182436.1\|985876_986701_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_CP039448.1\|WP_000769690.1\|997131_997566_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_CP039448.1\|WP_001124491.1\|984508_985825_-\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|184103
NZ_CP039448.1\|WP_000682089.1\|997822_998008_-\|YjzD-family-protein	unknown	unknown	gnl\|CDD\|371396
NZ_CP039448.1\|WP_001044212.1\|987776_989591_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP039448.1\|WP_000695347.1\|996305_996821_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|224793
NZ_CP039448.1\|WP_001047064.1\|992461_993331_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP039448.1\|WP_000404422.1\|994569_995211_+\|L-threonylcarbamoyladenylate-synthase	unknown	unknown	gnl\|CDD\|223088
NZ_CP039448.1\|WP_000619354.1\|993440_994586_+\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|223197
NZ_CP039448.1\|WP_000758211.1\|974146_974671_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP039448.1\|WP_000081240.1\|999255_1000500_+\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NZ_CP039448.1\|WP_000902813.1\|983947_984337_+\|YisL-family-protein	unknown	unknown	gnl\|CDD\|237465
NZ_CP039448.1\|WP_001100526.1\|998302_999244_+\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NZ_CP039448.1\|WP_000353962.1\|989793_992403_+\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_CP039448.1\|WP_149569688.1\|978898_982552_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_CP039448.1\|WP_000670755.1\|982717_983620_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP039448.1\|WP_000711897.1\|974686_975262_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP039448.1\|WP_000390575.1\|986814_987123_+\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
NZ_CP039448.1\|WP_000007965.1\|973566_974142_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP039448.1\|WP_149569687.1\|975421_978898_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_001182436.1\|985876_986701_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66336e-85
NZ_CP039448.1\|WP_000769690.1\|997131_997566_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	4.89876e-36
NZ_CP039448.1\|WP_001124491.1\|984508_985825_-\|CoA-disulfide-reductase	gnl\|CDD\|184103	PRK13512, PRK13512, coenzyme A disulfide reductase; Provisional.	0
NZ_CP039448.1\|WP_000682089.1\|997822_998008_-\|YjzD-family-protein	gnl\|CDD\|371396	pfam11151, DUF2929, Protein of unknown function (DUF2929). This family of proteins with unknown function appears to be restricted to Firmicutes.	3.19261e-11
NZ_CP039448.1\|WP_001044212.1\|987776_989591_+\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.03079e-81
NZ_CP039448.1\|WP_000695347.1\|996305_996821_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	1.3728e-41
NZ_CP039448.1\|WP_001047064.1\|992461_993331_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.73485e-36
NZ_CP039448.1\|WP_000404422.1\|994569_995211_+\|L-threonylcarbamoyladenylate-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	2.09833e-60
NZ_CP039448.1\|WP_000619354.1\|993440_994586_+\|2-isopropylmalate-synthase	gnl\|CDD\|223197	COG0119, LeuA, Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism].	1.14533e-101
NZ_CP039448.1\|WP_000758211.1\|974146_974671_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.31712e-49
NZ_CP039448.1\|WP_000081240.1\|999255_1000500_+\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_CP039448.1\|WP_000902813.1\|983947_984337_+\|YisL-family-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	7.45228e-34
NZ_CP039448.1\|WP_001100526.1\|998302_999244_+\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	0
NZ_CP039448.1\|WP_000353962.1\|989793_992403_+\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CP039448.1\|WP_149569688.1\|978898_982552_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP039448.1\|WP_000670755.1\|982717_983620_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
NZ_CP039448.1\|WP_000711897.1\|974686_975262_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
NZ_CP039448.1\|WP_000390575.1\|986814_987123_+\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.55915e-41
NZ_CP039448.1\|WP_000007965.1\|973566_974142_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.15479e-40
NZ_CP039448.1\|WP_149569687.1\|975421_978898_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0

>NZ_CP039448.1|WP_000390575.1|986814_987123_+|metal-sulfur-cluster-assembly-factor
MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDEGVCTVDMTLTSMGCPMGPQIIDQVKTVLAEIPEIQDTEVNIVWSPPWTKDMMSRYAKIALGVS
>NZ_CP039448.1|WP_001182436.1|985876_986701_-|Cof-type-HAD-IIB-family-hydrolase
MQPHLICLDLDGTLLNDNKEISSYTKQVLNELQQRGHQIMIATGRPYRASQMYYHELNLTTPIVNFNGAYVHHPKDKNFKTCHEILDLGIAQNIIQGLQQYQVSNIIAEVKDYVFINNHDPRLFEGFSMGNPRIQTGNLLVHLKESPTSILIEAEESKIPEIKNMLTHFYADHIEHRRWGAPFPVIEIVKLGINKARGIEQVRQFLNIDRNNIIAFGDEDNDIEMIEYARHGVAMENGLQELKDVANNITFNNNEDGIGRYLNDFFNLNIRYYC
>NZ_CP039448.1|WP_001124491.1|984508_985825_-|CoA-disulfide-reductase
MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASAHSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIVAINGNEITFKSGRVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
>NZ_CP039448.1|WP_000902813.1|983947_984337_+|YisL-family-protein
MLHLHILSWVLAIILFIATYLNISKNQGGTPYFKPLHMVLRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPISKLFGIG
>NZ_CP039448.1|WP_000670755.1|982717_983620_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>NZ_CP039448.1|WP_149569688.1|978898_982552_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTDWLDQLVTPYEEEAQQAELIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMRRVLEGGFIDIPYLTGHEFGARLPNITAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEVAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIHSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISKVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_CP039448.1|WP_149569687.1|975421_978898_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSMKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDSELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYKDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLRALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIGALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNINIDDEFGGEQ
>NZ_CP039448.1|WP_000711897.1|974686_975262_+|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>NZ_CP039448.1|WP_000758211.1|974146_974671_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLVDKKDIIGNISLRYYPFSKWTIQFKS
>NZ_CP039448.1|WP_000007965.1|973566_974142_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>NZ_CP039448.1|WP_001044212.1|987776_989591_+|acetyltransferase
MNKTKGFTKYKKMIYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSENIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQYYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYIIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWYKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
>NZ_CP039448.1|WP_000353962.1|989793_992403_+|ATP-dependent-chaperone-ClpB
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEALAKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQGKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEITEPTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE
>NZ_CP039448.1|WP_001047064.1|992461_993331_-|LysR-family-transcriptional-regulator
MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLNVKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIATFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVCEGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYEKAQFLSINDVHTSIKLIEMNQGISFLPLYITTNSDYNISVINTKILQAPISFTYIYSKKEIPEILVFIKSFKKYIANEQL
>NZ_CP039448.1|WP_000619354.1|993440_994586_+|2-isopropylmalate-synthase
MIRIQDNTIRDGMQQSNVRKSLFIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDILSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDCLEILKKDKKGVDICFEDATRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFNYFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITILTKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMYQYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVAPEDTVDLLQIIKRRSKDGNFK
>NZ_CP039448.1|WP_000404422.1|994569_995211_+|L-threonylcarbamoyladenylate-synthase
MEILNDSVKSFEKLYLQLQDGFPVIVPTDTNYNLCSLPNNDLCIDKIFEYKKRSKDKPLSLFIDKPEDWKLYGDNQNTEIVDKLVEIFWPGPLNIILKNKTSYNYMLNNSDSIAIGCVQNKTMRRFISYINSPIAITSANISGTADDILITENEAIKHMGENVRYMLRSQNKTNYKTSSTIIKVTDNKIELLREGDIKFEEIKERLGTGIIYE
>NZ_CP039448.1|WP_000695347.1|996305_996821_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MKIKTEFKGNNIPYEYAAGADVSDSINGNPIKSFPFEVTELPEGTKYLAWSLIDYDAIPVCGFAWIHWSVANVSVSGNSISIKADLSRTKGDYVQGKNSFTSGLLAEDFSEIENHYVGPTPPDKDHQYELTVYALGHSLNLKNGFYLNEFLKEVNQHKIDQTSINLIGRKI
>NZ_CP039448.1|WP_000769690.1|997131_997566_+|MAP-domain-containing-protein
MKLKSFITVTLALGMIATTGATVASNEVSAAEKDKLPATQKAKEMQNVPYTIAVDGIMAFNQSYLNLPKDSQLSYLDLGNKVKALLYDERGVTPEKIRNAKSAVYTITWKDGSKKEVDLKKDSYTANLFDSNSIKQIDINVKTK
>NZ_CP039448.1|WP_000682089.1|997822_998008_-|YjzD-family-protein
MKHLVTFFWALLLMQMVNFVLNSLVGGDSLNVVNPIIMAVLFTIFTAIFAAVIKPPKDSSQ
>NZ_CP039448.1|WP_001100526.1|998302_999244_+|ketoacyl-ACP-synthase-III
MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK
>NZ_CP039448.1|WP_000081240.1|999255_1000500_+|beta-ketoacyl-ACP-synthase-II
MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSALSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITYAMSNSLGFGGHNAVLVFKKFEA

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Crispr_ID: NZ_CP039448_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_4

1105653-1105745

Orphan

Consensus_repeat	Method
AAAAGCCCCTAACAACTAAAGGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_4

>merge|NZ_CP039448|4|1105653-1105745|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAGGTTGTAAGGTAAAAGAGGGATACTTGCGTCGAGCGCAAGCATAAAAGCCCCTAACAACTAAAAGTTGTAAGG

>NZ_CP039448|4|4|1105653-1105745|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAGGTTGTAAGG	TAAAAGAGGGATACTTGCGTCGAGCGCAAGCAT
AAAAGCCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_149569690.1\|1112337_1113699_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP039448.1\|WP_000437472.1\|1109682_1109949_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_CP039448.1\|WP_000685063.1\|1107760_1108933_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP039448.1\|WP_001797763.1\|1107356_1107560_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000505962.1\|1108986_1109529_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NZ_CP039448.1\|WP_000273256.1\|1102381_1103188_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP039448.1\|WP_000638454.1\|1113695_1114715_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NZ_CP039448.1\|WP_001289624.1\|1111906_1112140_-\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274
NZ_CP039448.1\|WP_000238670.1\|1098787_1099354_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NZ_CP039448.1\|WP_000040057.1\|1109951_1111670_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP039448.1\|WP_000064214.1\|1105754_1105889_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_071665620.1\|1102079_1102277_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000709285.1\|1099368_1100847_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP039448.1\|WP_001101926.1\|1100868_1102116_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NZ_CP039448.1\|WP_000483727.1\|1096279_1097764_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_CP039448.1\|WP_000921971.1\|1103180_1104581_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP039448.1\|WP_000033477.1\|1104595_1105171_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NZ_CP039448.1\|WP_000030810.1\|1097756_1098785_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP039448.1\|WP_000032747.1\|1094111_1096301_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP039448.1\|WP_000009075.1\|1106040_1107336_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_149569690.1\|1112337_1113699_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	8.28482e-166
NZ_CP039448.1\|WP_000505962.1\|1108986_1109529_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00760449
NZ_CP039448.1\|WP_000273256.1\|1102381_1103188_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.49952e-29
NZ_CP039448.1\|WP_000638454.1\|1113695_1114715_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	4.77009e-76
NZ_CP039448.1\|WP_001289624.1\|1111906_1112140_-\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	4.9181e-16
NZ_CP039448.1\|WP_000709285.1\|1099368_1100847_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP039448.1\|WP_000040057.1\|1109951_1111670_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP039448.1\|WP_000032747.1\|1094111_1096301_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP039448.1\|WP_000685063.1\|1107760_1108933_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
NZ_CP039448.1\|WP_001101926.1\|1100868_1102116_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP039448.1\|WP_000030810.1\|1097756_1098785_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP039448.1\|WP_000483727.1\|1096279_1097764_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_CP039448.1\|WP_000033477.1\|1104595_1105171_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NZ_CP039448.1\|WP_000238670.1\|1098787_1099354_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	1.52687e-91
NZ_CP039448.1\|WP_000921971.1\|1103180_1104581_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.91329e-64
NZ_CP039448.1\|WP_000437472.1\|1109682_1109949_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51

>NZ_CP039448.1|WP_000033477.1|1104595_1105171_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NZ_CP039448.1|WP_000921971.1|1103180_1104581_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLENVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NZ_CP039448.1|WP_000273256.1|1102381_1103188_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDVIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>NZ_CP039448.1|WP_071665620.1|1102079_1102277_-|hypothetical-protein
MFIQTCCGASFLLHIHNHKFGTEINVLDSTTKKAMKKSIVIDSFIANLSIFKYTYLSCSALFAMS
>NZ_CP039448.1|WP_001101926.1|1100868_1102116_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSSLVKQVFVIPGNEAMTPIAEVHTEISESDHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGNRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVHDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>NZ_CP039448.1|WP_000709285.1|1099368_1100847_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTGEALDILKQKKNVRLLEIDMIIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NZ_CP039448.1|WP_000238670.1|1098787_1099354_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NZ_CP039448.1|WP_000030810.1|1097756_1098785_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDLFLEPTKLYVKPVLTLKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGDIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>NZ_CP039448.1|WP_000483727.1|1096279_1097764_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSNQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NZ_CP039448.1|WP_000032747.1|1094111_1096301_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKNYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGVLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NZ_CP039448.1|WP_000064214.1|1105754_1105889_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NZ_CP039448.1|WP_000009075.1|1106040_1107336_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHYMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NZ_CP039448.1|WP_001797763.1|1107356_1107560_-|hypothetical-protein
MILQMDNFSTILFALKLCIQFSILNSHHLNQSNLVTKKVLSINFIDLYLNKLEIYLTYSVHIKMFNR
>NZ_CP039448.1|WP_000685063.1|1107760_1108933_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NZ_CP039448.1|WP_000505962.1|1108986_1109529_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENINEKGAMPTTIKELNERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERVMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NZ_CP039448.1|WP_000437472.1|1109682_1109949_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NZ_CP039448.1|WP_000040057.1|1109951_1111670_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMNGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NZ_CP039448.1|WP_001289624.1|1111906_1112140_-|glutaredoxin-family-protein
MSEIIVYTQNDCPPCTFVKNYLTEHQIVFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NZ_CP039448.1|WP_149569690.1|1112337_1113699_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYLAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NZ_CP039448.1|WP_000638454.1|1113695_1114715_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFTLASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS

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Crispr_ID: NZ_CP039448_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_5

1264493-1264585

Unclear

Consensus_repeat	Method
TAAGAAACAGTAATCAATAAATTGATAACT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP039448_5

>merge|NZ_CP039448|5|1264493-1264585|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACTAATAAGCGGAACGCCTGAGCTAAAGCTCATGCATAAGAAACAGTAATCAATAAATTGATAACT

>NZ_CP039448|5|5|1264493-1264585|CRISPRCasFinder
TAAGAAACAGTAATCAATAAATTGATAACT	AATAAGCGGAACGCCTGAGCTAAAGCTCATGCA
TAAGAAACAGTAATCAATAAATTGATAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000623917.1\|1257061_1258708_+\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|224378
NZ_CP039448.1\|WP_001151491.1\|1258897_1260958_+\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
NZ_CP039448.1\|WP_000517908.1\|1256041_1256230_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP039448.1\|WP_000531320.1\|1270704_1271037_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP039448.1\|WP_000171418.1\|1256672_1257047_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP039448.1\|WP_000426914.1\|1264674_1264908_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP039448.1\|WP_000164340.1\|1254367_1255012_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_CP039448.1\|WP_000239738.1\|1261736_1262723_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_CP039448.1\|WP_001043838.1\|1262715_1263642_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP039448.1\|WP_000687320.1\|1273741_1274479_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP039448.1\|WP_000043237.1\|1265023_1265755_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_CP039448.1\|WP_000268754.1\|1272775_1273051_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NZ_CP039448.1\|WP_000007686.1\|1269467_1270718_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP039448.1\|WP_000547905.1\|1255018_1255660_+\|thiamine-diphosphokinase	unknown	unknown	gnl\|CDD\|224480
NZ_CP039448.1\|WP_000181404.1\|1274581_1274932_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP039448.1\|WP_149569691.1\|1265901_1269468_+\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NZ_CP039448.1\|WP_001261990.1\|1273238_1273742_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP039448.1\|WP_000167269.1\|1263634_1264369_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP039448.1\|WP_001548538.1\|1261159_1261732_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_CP039448.1\|WP_000863474.1\|1271062_1272430_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000623917.1\|1257061_1258708_+\|DAK2-domain-containing-protein	gnl\|CDD\|224378	COG1461, COG1461, Predicted kinase related to dihydroxyacetone kinase [General function prediction only].	0
NZ_CP039448.1\|WP_001151491.1\|1258897_1260958_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP039448.1\|WP_000517908.1\|1256041_1256230_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NZ_CP039448.1\|WP_000531320.1\|1270704_1271037_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
NZ_CP039448.1\|WP_000171418.1\|1256672_1257047_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
NZ_CP039448.1\|WP_000426914.1\|1264674_1264908_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_CP039448.1\|WP_000164340.1\|1254367_1255012_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	4.67332e-114
NZ_CP039448.1\|WP_000239738.1\|1261736_1262723_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	6.04516e-178
NZ_CP039448.1\|WP_001043838.1\|1262715_1263642_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	9.10665e-134
NZ_CP039448.1\|WP_000687320.1\|1273741_1274479_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.74382e-164
NZ_CP039448.1\|WP_000043237.1\|1265023_1265755_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NZ_CP039448.1\|WP_000268754.1\|1272775_1273051_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NZ_CP039448.1\|WP_000007686.1\|1269467_1270718_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NZ_CP039448.1\|WP_000547905.1\|1255018_1255660_+\|thiamine-diphosphokinase	gnl\|CDD\|224480	COG1564, THI80, Thiamine pyrophosphokinase [Coenzyme metabolism].	1.16343e-81
NZ_CP039448.1\|WP_000181404.1\|1274581_1274932_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NZ_CP039448.1\|WP_149569691.1\|1265901_1269468_+\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NZ_CP039448.1\|WP_001261990.1\|1273238_1273742_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	7.15666e-69
NZ_CP039448.1\|WP_000167269.1\|1263634_1264369_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
NZ_CP039448.1\|WP_001548538.1\|1261159_1261732_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
NZ_CP039448.1\|WP_000863474.1\|1271062_1272430_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0

>NZ_CP039448.1|WP_000167269.1|1263634_1264369_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NZ_CP039448.1|WP_001043838.1|1262715_1263642_+|ACP-S-malonyltransferase
MNKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>NZ_CP039448.1|WP_000239738.1|1261736_1262723_+|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYKLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>NZ_CP039448.1|WP_001548538.1|1261159_1261732_+|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>NZ_CP039448.1|WP_001151491.1|1258897_1260958_+|ATP-dependent-DNA-helicase-RecG
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQNQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDCLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDNVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>NZ_CP039448.1|WP_000623917.1|1257061_1258708_+|DAK2-domain-containing-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAVEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKLDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLIEMLAEDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
>NZ_CP039448.1|WP_000171418.1|1256672_1257047_+|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>NZ_CP039448.1|WP_000517908.1|1256041_1256230_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NZ_CP039448.1|WP_000547905.1|1255018_1255660_+|thiamine-diphosphokinase
MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFFSVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGRLDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTDDVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN
>NZ_CP039448.1|WP_000164340.1|1254367_1255012_+|ribulose-phosphate-3-epimerase
MTKLYPSLLSVDFLVLQHELKRLEEAGVDGVHFDVMDGQFVPNISIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQMIKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNAIKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG
>NZ_CP039448.1|WP_000426914.1|1264674_1264908_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NZ_CP039448.1|WP_000043237.1|1265023_1265755_+|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NZ_CP039448.1|WP_149569691.1|1265901_1269468_+|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVRDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLIELLENISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIKSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKSSLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLNDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEATLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NZ_CP039448.1|WP_000007686.1|1269467_1270718_+|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGAK
>NZ_CP039448.1|WP_000531320.1|1270704_1271037_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>NZ_CP039448.1|WP_000863474.1|1271062_1272430_+|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NZ_CP039448.1|WP_000268754.1|1272775_1273051_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NZ_CP039448.1|WP_001261990.1|1273238_1273742_+|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEYYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>NZ_CP039448.1|WP_000687320.1|1273741_1274479_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFAGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NZ_CP039448.1|WP_000181404.1|1274581_1274932_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

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Crispr_ID: NZ_CP039448_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_6

1469740-1469819

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_6

>merge|NZ_CP039448|6|1469740-1469819|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGGCTTTCCGCAGCTACTATGTTGGGGACCCGCCAACTTGCACTTTATTGTAAGCTG

>NZ_CP039448|6|6|1469740-1469819|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTG	GCTTTCCGCAGCTACTATGTTGGGGACCCG
CCAACTTGCACTTTATTGTAAGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000166795.1\|1467210_1468566_-\|sensor-histidine-kinase-ArlS	unknown	unknown	gnl\|CDD\|223715
NZ_CP039448.1\|WP_149569694.1\|1464123_1466922_-\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NZ_CP039448.1\|WP_000084773.1\|1470363_1470978_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_CP039448.1\|WP_000160908.1\|1470994_1472065_-\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|171505
NZ_CP039448.1\|WP_000801007.1\|1474667_1474889_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226885
NZ_CP039448.1\|WP_000473654.1\|1474888_1475389_-\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225101
NZ_CP039448.1\|WP_000913315.1\|1475400_1475829_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP039448.1\|WP_000166052.1\|1476444_1477284_-\|fatty-acid-kinase-FakB2	unknown	unknown	gnl\|CDD\|273257
NZ_CP039448.1\|WP_000175746.1\|1477298_1477778_-\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NZ_CP039448.1\|WP_000620194.1\|1472076_1472586_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP039448.1\|WP_000159902.1\|1475821_1476355_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|237269
NZ_CP039448.1\|WP_001283670.1\|1458348_1460235_-\|nitric-oxide-reductase-activation-protein-NorD	unknown	unknown	gnl\|CDD\|226921
NZ_CP039448.1\|WP_000192137.1\|1468562_1469222_-\|response-regulator-transcription-factor-ArlR	unknown	unknown	gnl\|CDD\|223816
NZ_CP039448.1\|WP_001115452.1\|1462841_1464110_-\|dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NZ_CP039448.1\|WP_000334509.1\|1461452_1462262_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319934
NZ_CP039448.1\|WP_000902174.1\|1461220_1461424_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000342123.1\|1472985_1474476_-\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NZ_CP039448.1\|WP_000138424.1\|1455570_1456707_+\|toxic-anion-resistance-protein	unknown	unknown	gnl\|CDD\|377557
NZ_CP039448.1\|WP_001185421.1\|1460248_1461040_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP039448.1\|WP_001039275.1\|1456780_1458124_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|224039

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000166795.1\|1467210_1468566_-\|sensor-histidine-kinase-ArlS	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.27236e-48
NZ_CP039448.1\|WP_149569694.1\|1464123_1466922_-\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NZ_CP039448.1\|WP_000084773.1\|1470363_1470978_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	6.60547e-49
NZ_CP039448.1\|WP_000160908.1\|1470994_1472065_-\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|171505	PRK12446, PRK12446, undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed.	3.82367e-132
NZ_CP039448.1\|WP_000801007.1\|1474667_1474889_-\|hypothetical-protein	gnl\|CDD\|226885	COG4479, COG4479, Uncharacterized protein conserved in bacteria [Function unknown].	1.53726e-28
NZ_CP039448.1\|WP_000473654.1\|1474888_1475389_-\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	9.03019e-68
NZ_CP039448.1\|WP_000913315.1\|1475400_1475829_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	9.76591e-81
NZ_CP039448.1\|WP_000166052.1\|1476444_1477284_-\|fatty-acid-kinase-FakB2	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	8.59745e-119
NZ_CP039448.1\|WP_000620194.1\|1472076_1472586_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.78214e-09
NZ_CP039448.1\|WP_000159902.1\|1475821_1476355_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|237269	PRK13014, PRK13014, methionine sulfoxide reductase A; Provisional.	4.15064e-107
NZ_CP039448.1\|WP_001283670.1\|1458348_1460235_-\|nitric-oxide-reductase-activation-protein-NorD	gnl\|CDD\|226921	COG4548, NorD, Nitric oxide reductase activation protein [Inorganic ion transport and metabolism].	0
NZ_CP039448.1\|WP_000192137.1\|1468562_1469222_-\|response-regulator-transcription-factor-ArlR	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.42624e-89
NZ_CP039448.1\|WP_001115452.1\|1462841_1464110_-\|dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NZ_CP039448.1\|WP_000175746.1\|1477298_1477778_-\|dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	8.71869e-81
NZ_CP039448.1\|WP_000334509.1\|1461452_1462262_-\|hypothetical-protein	gnl\|CDD\|319934	cd08346, PcpA_N_like, N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The N-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	8.74417e-08
NZ_CP039448.1\|WP_000342123.1\|1472985_1474476_-\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	7.13135e-124
NZ_CP039448.1\|WP_000138424.1\|1455570_1456707_+\|toxic-anion-resistance-protein	gnl\|CDD\|377557	pfam05816, TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.	2.13715e-131
NZ_CP039448.1\|WP_001185421.1\|1460248_1461040_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	4.42262e-45
NZ_CP039448.1\|WP_001039275.1\|1456780_1458124_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|224039	COG1114, BrnQ, Branched-chain amino acid permeases [Amino acid transport and metabolism].	1.47543e-160

>NZ_CP039448.1|WP_000192137.1|1468562_1469222_-|response-regulator-transcription-factor-ArlR
MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQPQKDIIDVNGITIDKNAFKVTVNGAEIELTKTEYDLLYLLAENKNHVMQREQILNHVWGYNSEVETNVVDVYIRYLRNKLKPYDRDKMIETVRGVGYVIR
>NZ_CP039448.1|WP_000166795.1|1467210_1468566_-|sensor-histidine-kinase-ArlS
MTKRKLRNNWIIVTTMITFVTIFLFCLIIIFFLKDTLHNSELDDAERSSSDINNLFHSKPVKDISALDLNASLGNFQEIIIYDEHNNKLFETSNDNTVRVEPGYEHRYFDRVIKKRYKGIDYLIIKEPITTQDFKGYSLLIHSLENYDNIVKSLYIIALAFGVIATIITATISYVFSTQITKPLVSLSNKMIEIRRDGFQNKLQLNTNYEEIDNLANTFNEMMSQIEESFNQQRQFVEDASHELRTPLQIIQGHLNLIQRWGKKDPAVLEESLNISIEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDEIRSRIHSLKQLHPDYQFDTDLTSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKKIKVKTRLKNKQKIIEITDNGIGIPEEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQLNGGSIKIKSEINKGTTFKIIF
>NZ_CP039448.1|WP_149569694.1|1464123_1466922_-|2-oxoglutarate-dehydrogenase-E1-component
MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLFSTIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNSEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDLVGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMNSFIEQVQKELRQAHDKINKADKMDNPDMEKPADLALPLQADEQSFTFDHLKEINDALLTYPDGFNILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHRHAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEAQYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAAENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGGFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENALKNN
>NZ_CP039448.1|WP_001115452.1|1462841_1464110_-|dihydrolipoyllysine-residue-succinyltransferase
MPEVKVPELAESITEGTIAEWLKNVGDSVEKGEAILELETDKVNVEVVSEEAGVLSEQLASEGDTVEVGQAIAVIGEGSGNASKENSNDNTPQQNEETNNKKEETTNKSADKAEVNQTTDDNQQRVNATPSARRYARENGVNLAEVSPKTNDLVRKEDIDKKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLTTFNEVDMTNVMELRKRKKDQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDDMITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVNGSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYDHRIIDGKEAVGFLKTIKELIENPEDLLLES
>NZ_CP039448.1|WP_000334509.1|1461452_1462262_-|hypothetical-protein
MCGLRSITLGTTNIEQTKHFMVDILGLNCEELLENSIRFGDADISPGTRLQFIQVPSEQLEESHFVGIGLRTPTDSGLEEYAEILSSKEIPFTTTKELNGNKYFSFEDNNGHIFSIYSNENNYGVGLGMPSFESAVNPLHQVQGLGPVILKVNHVDITGQILTNIFGLEVFAEYQPFDNADYHVQVFKIGTGGLGGEIHLMPVETEMTMPEYGAVDQVEFETKDADFFNQAKSRLDEVEIPYQTLEQDDIESIRITENSGLSFIFTLQK
>NZ_CP039448.1|WP_000902174.1|1461220_1461424_-|hypothetical-protein
MLHETWKERTPIKKVEVINTDAKKFTVSDMLTVGKQYDVINETEEYYQIIDNSGLIGGYYKTYFKEV
>NZ_CP039448.1|WP_001185421.1|1460248_1461040_-|MoxR-family-ATPase
MALKHYKNSDSTVFNDAKALFDLNKNILLKGPTGSGKTKLAETLSEVVDTPMHQVNCSVDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYIDEINMAKPETLPVLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLPMNEALKNRFVVIHVDYIDGDILKNVIKEQSLLQDDKQIEQIIKFNEDLRTMSKQGQISEEAASIRALLDLCDLITVMPVERAIKRTIIDKLEDEREQQAIYNAVELNF
>NZ_CP039448.1|WP_001283670.1|1458348_1460235_-|nitric-oxide-reductase-activation-protein-NorD
MSDRFIKFNDEQLDAKQVMMLQDLARLLLKNEQTQVKIQKFPYYNPVQNVLITSWFWSHRPSHIEMAGLKTDVMLAAYGYHMMDVQIVNEVVQDKTFKHPKFYQQLFKLLEDMRVLNSIKVERPSTAKLIDLRLDTRISYTESQIKVYRTKTQYTDLLFLYLEHAFLSQDFFDIPSIHSDLDDILVNMFLYLPNFFQNQNSEDNMYLAQRIMYQVDDILKEDMLNEYYYLPKTLYNTLASPEFEDLKRTDASQVDGQDDTSEDDDNQSEKADSKSADSESKGGAYLEMELHEGQNSETLGNDEAREGDATDDMTDMMTKKGKGSNDTLNREEGDAVGQSQAFQLDGVNKNVEIKWQIPEIEPQYVLEYQESKQDVQYEIKDLIQIIKKTIEREQRDARFNLTKGRLQKDLINWFIDDQYKLFYKKQDLSKSFDATFTLLIDASASMHDKMAETKKGVVLFHETLKALNIKHEILSFSEDAFDSDEHAQPNIINEIINYDYSTFEKDGPRIMALEPQDDNRDGVAIRVASERLMRRNQHQRFLIVFSDGEPSAFNYSQDGIIDTYEAVEMSRKFGIEVFNVFLSQDPITEDVEQTIHNIYGQYAIFVEGVAHLPGHLSPLLKKLLLKSL
>NZ_CP039448.1|WP_001039275.1|1456780_1458124_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFVLTGIGLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSFEMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMIIKGYLDFSGNSAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGITKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLTTMASTGFGSFGKYLLGIIVALACLTTACGLIVAVSEYFHRIVPKVSYKAFVLVFILMSFIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAKFIPTKRISQQIPVIIVFILSIFSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE
>NZ_CP039448.1|WP_000138424.1|1455570_1456707_+|toxic-anion-resistance-protein
MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTISKQINPLDNEGLLAFGSGLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPNELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDTLYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFIDRLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIETIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS
>NZ_CP039448.1|WP_000084773.1|1470363_1470978_-|phosphatase-PAP2-family-protein
MSQWKRISLLIVFTLVFGIIAFFHESRLGKWIDNEVYEFIYSSESFITTSIMLGATKVGEVWAMLCISLLLVAYLMLKRHKIEALFFALTMALSGILNPALKNIFDRERPTLLRLIDITGFSFPSGHAMGSTAYFGSGIYLLNRLNQGNSKGILIGLCAAMILLISISRVYLGVHYPTDIIAGIIGGVFCIILSTLLLRNKLIN
>NZ_CP039448.1|WP_000160908.1|1470994_1472065_-|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDDQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKAIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
>NZ_CP039448.1|WP_000620194.1|1472076_1472586_-|GNAT-family-N-acetyltransferase
MIRLGKMSDLDQILNLVEEAKELMKEHDNEQWDDQYPLLEHFEEDIAKDYLYVLEENDKIYGFIVVDQDQAEWYDDIDWPVNREGAFVIHRLTGSKEYKGAATELFNYVIDVVKARGAEVILTDTFALNKPAQGLFAKFGFHKVGEQLMEYPPYDKGEPFYAYYKNLKE
>NZ_CP039448.1|WP_000342123.1|1472985_1474476_-|S41-family-peptidase
MDDKQHKSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKISGLNKTDQANLNKIENVYKILNSDYFKKQNSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGIITINKFQNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYHKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEKANKHDDVLDKLINILK
>NZ_CP039448.1|WP_000801007.1|1474667_1474889_-|hypothetical-protein
MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILSDYIETHGDFTLPMSVFDDLYEEYTEWLKF
>NZ_CP039448.1|WP_000473654.1|1474888_1475389_-|PTS-glucose-transporter-subunit-IIA
MFKKLFGKGKEVQKDIAIYAPLTGEYVKIEDIPDPVFAQKMMGEGFGINPTEGEVVSPIAGRVDNVFPTKHAIGLKADNGLELLVHIGLDTVQLDGEGFEVLVSSGDEVNVGDPLVRFNLEYINNNAKSVISPIIITNTDQAASINIYDENAVIKGETKVIDVTMN
>NZ_CP039448.1|WP_000913315.1|1475400_1475829_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMLRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
>NZ_CP039448.1|WP_000159902.1|1475821_1476355_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYEQVCTNQTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYHDEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQRGSGRKAFIESHWGNQNA
>NZ_CP039448.1|WP_000166052.1|1476444_1477284_-|fatty-acid-kinase-FakB2
MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGAEIISIHLSSGLSGTFNTAYQASQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVNKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSVGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
>NZ_CP039448.1|WP_000175746.1|1477298_1477778_-|dihydrofolate-reductase
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

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Crispr_ID: NZ_CP039448_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_7

2016574-2016655

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACCTGCATT	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP039448_7

>merge|NZ_CP039448|7|2016574-2016655|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCATTACCTGTAGAATTTCTTTTTTCGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCATT

>NZ_CP039448|7|7|2016574-2016655|CRISPRCasFinder
TGTTGGGGCCCCGCCAACCTGCATT	ACCTGTAGAATTTCTTTTTTCGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000548782.1\|2024143_2024674_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP039448.1\|WP_001110179.1\|2015029_2015416_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000613738.1\|2022205_2022760_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP039448.1\|WP_025174552.1\|2018338_2018752_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001790679.1\|2021896_2021989_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000544973.1\|2018976_2019708_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP039448.1\|WP_000140176.1\|2022826_2023897_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP039448.1\|WP_000999708.1\|2016919_2017906_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP039448.1\|WP_000228666.1\|2010300_2010765_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP039448.1\|WP_000949467.1\|2021314_2021815_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP039448.1\|WP_000149064.1\|2014313_2015015_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP039448.1\|WP_000037087.1\|2011324_2012542_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP039448.1\|WP_000153526.1\|2012654_2013284_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP039448.1\|WP_000428172.1\|2010771_2011047_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000180460.1\|2009953_2010154_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NZ_CP039448.1\|WP_078065149.1\|2008694_2009951_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP039448.1\|WP_000636142.1\|2015632_2016391_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP039448.1\|WP_001017131.1\|2013273_2014317_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP039448.1\|WP_001790257.1\|2018780_2018891_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001250333.1\|2019709_2021023_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000548782.1\|2024143_2024674_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.50924e-11
NZ_CP039448.1\|WP_000613738.1\|2022205_2022760_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NZ_CP039448.1\|WP_000544973.1\|2018976_2019708_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
NZ_CP039448.1\|WP_000140176.1\|2022826_2023897_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP039448.1\|WP_000999708.1\|2016919_2017906_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.82639e-75
NZ_CP039448.1\|WP_000228666.1\|2010300_2010765_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP039448.1\|WP_000949467.1\|2021314_2021815_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_CP039448.1\|WP_000149064.1\|2014313_2015015_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP039448.1\|WP_000037087.1\|2011324_2012542_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	7.61989e-85
NZ_CP039448.1\|WP_000153526.1\|2012654_2013284_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	8.44874e-79
NZ_CP039448.1\|WP_000180460.1\|2009953_2010154_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
NZ_CP039448.1\|WP_078065149.1\|2008694_2009951_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP039448.1\|WP_000636142.1\|2015632_2016391_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NZ_CP039448.1\|WP_001017131.1\|2013273_2014317_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP039448.1\|WP_001250333.1\|2019709_2021023_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	2.56502e-98

>NZ_CP039448.1|WP_000636142.1|2015632_2016391_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP039448.1|WP_001110179.1|2015029_2015416_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP039448.1|WP_000149064.1|2014313_2015015_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP039448.1|WP_001017131.1|2013273_2014317_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP039448.1|WP_000153526.1|2012654_2013284_-|response-regulator-transcription-factor
MTIKVLFVDDHEMVRIGISSYLSTQRDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP039448.1|WP_000037087.1|2011324_2012542_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKEDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYAEDTNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP039448.1|WP_000428172.1|2010771_2011047_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP039448.1|WP_000228666.1|2010300_2010765_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP039448.1|WP_000180460.1|2009953_2010154_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>NZ_CP039448.1|WP_078065149.1|2008694_2009951_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIEGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>NZ_CP039448.1|WP_000999708.1|2016919_2017906_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYDRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKAHEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP039448.1|WP_025174552.1|2018338_2018752_-|hypothetical-protein
MKPTKVILRDASYVHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEIKFEFALFDSDMDNLKHMEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVTKSDFNKFINELASLH
>NZ_CP039448.1|WP_001790257.1|2018780_2018891_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP039448.1|WP_000544973.1|2018976_2019708_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>NZ_CP039448.1|WP_001250333.1|2019709_2021023_-|Mur-ligase-family-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP039448.1|WP_000949467.1|2021314_2021815_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP039448.1|WP_001790679.1|2021896_2021989_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP039448.1|WP_000613738.1|2022205_2022760_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP039448.1|WP_000140176.1|2022826_2023897_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP039448.1|WP_000548782.1|2024143_2024674_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADAYFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: NZ_CP039448_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_8

2076345-2076430

Orphan

Consensus_repeat	Method
TGTTGAGGCCCCACCCCAACTTACATTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_8

>merge|NZ_CP039448|8|2076345-2076430|CRISPRCasFinder
TGTTGAGGCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTATGTTGGGGCCCCACCCCAACTTACATTGT

>NZ_CP039448|8|8|2076345-2076430|CRISPRCasFinder
TGTTGAGGCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTA
TGTTGGGGCCCCACCCCAACTTACATTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000206634.1\|2074906_2076130_+\|ArgE/DapE-family-deacylase	unknown	unknown	gnl\|CDD\|181490
NZ_CP039448.1\|WP_029625651.1\|2081613_2082081_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001293084.1\|2083493_2084063_-\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|226251
NZ_CP039448.1\|WP_001068527.1\|2067201_2068488_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181512
NZ_CP039448.1\|WP_078065371.1\|2084059_2084272_-\|pathogenicity-island-family-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000691584.1\|2065564_2065945_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_CP039448.1\|WP_000595398.1\|2072377_2073394_-\|bi-component-leukocidin-LukGH-subunit-G	unknown	unknown	gnl\|CDD\|369625
NZ_CP039448.1\|WP_029625650.1\|2082093_2083107_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001190614.1\|2085667_2086009_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000990056.1\|2066903_2067002_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000824908.1\|2078776_2079625_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225852
NZ_CP039448.1\|WP_001045084.1\|2076570_2077878_+\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223246
NZ_CP039448.1\|WP_000239607.1\|2070892_2071885_+\|sphingomyelin-phosphodiesterase	unknown	unknown	gnl\|CDD\|132436
NZ_CP039448.1\|WP_000771371.1\|2084403_2084931_-\|spore-coat-protein	unknown	unknown	gnl\|CDD\|227864
NZ_CP039448.1\|WP_029625649.1\|2084983_2085637_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000645729.1\|2063990_2064671_-\|phenol-soluble-modulin-export-ABC-transporter-permease-subunit-PmtB	unknown	unknown	gnl\|CDD\|379133
NZ_CP039448.1\|WP_000681969.1\|2066485_2066662_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_029625652.1\|2079682_2080597_-\|iron-hydroxamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238558
NZ_CP039448.1\|WP_000791403.1\|2073415_2074471_-\|bi-component-leukocidin-LukGH-subunit-H	unknown	unknown	gnl\|CDD\|369625
NZ_CP039448.1\|WP_000991298.1\|2064671_2065568_-\|phenol-soluble-modulin-export-ABC-transporter-ATP-binding-protein-PmtA	unknown	unknown	gnl\|CDD\|224054

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000206634.1\|2074906_2076130_+\|ArgE/DapE-family-deacylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NZ_CP039448.1\|WP_001068527.1\|2067201_2068488_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181512	PRK08637, PRK08637, hypothetical protein; Provisional.	0
NZ_CP039448.1\|WP_000691584.1\|2065564_2065945_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	7.00479e-47
NZ_CP039448.1\|WP_000595398.1\|2072377_2073394_-\|bi-component-leukocidin-LukGH-subunit-G	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	2.97231e-99
NZ_CP039448.1\|WP_001293084.1\|2083493_2084063_-\|terminase-small-subunit	gnl\|CDD\|226251	COG3728, XtmA, Phage terminase, small subunit [DNA replication, recombination, and repair].	5.81461e-68
NZ_CP039448.1\|WP_000824908.1\|2078776_2079625_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.84798e-32
NZ_CP039448.1\|WP_001045084.1\|2076570_2077878_+\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.39244e-80
NZ_CP039448.1\|WP_000771371.1\|2084403_2084931_-\|spore-coat-protein	gnl\|CDD\|227864	COG5577, COG5577, Spore coat protein [Cell envelope biogenesis, outer membrane].	1.58611e-36
NZ_CP039448.1\|WP_000645729.1\|2063990_2064671_-\|phenol-soluble-modulin-export-ABC-transporter-permease-subunit-PmtB	gnl\|CDD\|379133	pfam13346, ABC2_membrane_5, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	2.19015e-11
NZ_CP039448.1\|WP_000239607.1\|2070892_2071885_+\|sphingomyelin-phosphodiesterase	gnl\|CDD\|132436	TIGR03395, Sphingomyelinase_C, sphingomyelin phosphodiesterase. Members of this family are bacterial proteins that act as sphingomyelin phosphodiesterase (EC 3.1.4.12), also called sphingomyelinase. Some members of this family have been shown to act as hemolysins. [Cellular processes, Pathogenesis].	2.38027e-136
NZ_CP039448.1\|WP_029625652.1\|2079682_2080597_-\|iron-hydroxamate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238558	cd01138, FeuA, Periplasmic binding protein FeuA. These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind their ligands in the cleft between these domains.	8.23694e-75
NZ_CP039448.1\|WP_000791403.1\|2073415_2074471_-\|bi-component-leukocidin-LukGH-subunit-H	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.0236e-77
NZ_CP039448.1\|WP_000991298.1\|2064671_2065568_-\|phenol-soluble-modulin-export-ABC-transporter-ATP-binding-protein-PmtA	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.46612e-72

>NZ_CP039448.1|WP_000206634.1|2074906_2076130_+|ArgE/DapE-family-deacylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKNGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLEDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINNVDSNKLSLDIPSNHRPVTSDKNNKLITTIKDVASSYVDKDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>NZ_CP039448.1|WP_000791403.1|2073415_2074471_-|bi-component-leukocidin-LukGH-subunit-H
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSPVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>NZ_CP039448.1|WP_000595398.1|2072377_2073394_-|bi-component-leukocidin-LukGH-subunit-G
MIKQLYKNITICSLAISTVLTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDEGKSKFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>NZ_CP039448.1|WP_000239607.1|2070892_2071885_+|sphingomyelin-phosphodiesterase
MVKKTKSNSLKKVATLALANLLLVGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
>NZ_CP039448.1|WP_001068527.1|2067201_2068488_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MNPLAQSLNEQLQQSNATAFAMLSDLGQNMFYPKGILSQSAEAKSTTYNATIGMATNKDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIVTNALTHGLSLVGDLFVNQDDTILLPEHNWGNYKLVFNTRNGANLQTYPIFDKDGHYTTDSLVEALQSYNKDKVIMILNYPNNPTGYTPTHEEVTTIVNAIKALADKGTKVIAVVDDAYYGLFYEDVYTQSLFTALSNLNSNAILPVRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIGVIALNATDIRIAFSCVEKEDIPHVFDSIAKAIDDLR
>NZ_CP039448.1|WP_000990056.1|2066903_2067002_-|hypothetical-protein
MMWWQEGMMTLITGGLLIIFRLWLELKWKNKK
>NZ_CP039448.1|WP_000681969.1|2066485_2066662_-|hypothetical-protein
MKHLTKIFVVLAIILFIVGYYLQATNHESQGIKLLLAAIMFMICAFISRSNDRRKNNK
>NZ_CP039448.1|WP_000691584.1|2065564_2065945_-|GntR-family-transcriptional-regulator
MKIILKNNSDFPIYEQIKQQVKQNILKGHVAPGEHLPSMRELAKDLQVSLITTKRAYEDLEKDGFVTTIRGKGTFVKEQDSSILKEKQFFTIENLVKELVNEAQAIEMSLEELQDILTFIYEEESS
>NZ_CP039448.1|WP_000991298.1|2064671_2065568_-|phenol-soluble-modulin-export-ABC-transporter-ATP-binding-protein-PmtA
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIRVLEEDMALNPIELKNRIGFVYAENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLDPLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGAIEDLDDELASLLIFEEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF
>NZ_CP039448.1|WP_000645729.1|2063990_2064671_-|phenol-soluble-modulin-export-ABC-transporter-permease-subunit-PmtB
MKALLIRNFKLRRYTLIIYVLLLTLYPFYIMLDSTKFFYLLQSFISPTILIIWILDAGHLFRLNRRLGGNDSYYFYMSLPVSKKQLLNANYITCIVLTLIGTLVISLYAYEADVIEPNSIYFSTAYAFVISNFLSIPIAFSQFTELRRVKVPYGIYVFTIIILVPFLFSIAIVLVNYFVLSQSSFPDLYSYVLNIGFLIISIVILIVNYFKQLNKINTRKFKGGSR
>NZ_CP039448.1|WP_001045084.1|2076570_2077878_+|TrkH-family-potassium-uptake-protein
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITTSILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQNMGLVEKIGNSFFQSVTTRTAGFNSIDIAIINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>NZ_CP039448.1|WP_000824908.1|2078776_2079625_-|class-I-SAM-dependent-methyltransferase
MKRLDGIPESMLIPLIARAKEYEYEKPIIKDALSKKIFDGLDDIYKNVTCDDMSQIGISIRSVIIDSVTKRLIKDNKNLIVINIGCGLDTRFQRFNNEKISWIDLDVPESIEIRKTFFKETDSYKMIAKSMLDYSWIEDVINYKFFNSKSNILFIFEGVLMYFDESVMTKLLHTIIKKFGDHNLTFAIEFCSKTIANNTKRHKSVSKLSSQPVFKYGYNDLNELDKVLPNKMKVINEYNYFDYHKKRWGLFGYCRYIPYLKKRLNNKIVIMEYKPAKLITHN
>NZ_CP039448.1|WP_029625652.1|2079682_2080597_-|iron-hydroxamate-ABC-transporter-substrate-binding-protein
MKRLIGILLCSLFILTACSTSVDKTSDSTKTIDYKIENGKTLKVPEKPKRVAVLTGFYVGDFIKLGIKPIAVSDITKDSSILKPYLKGVDYIGENDVEKVAKAKPDLIVVDAMDKNIKKYQKIAPTVPYTYNKYNHKEILKEIGKLTNNEDKAKKWIEEWEDKTRKDKKEIQSKIGQATASVFEPDEKQIYIYNSTWGRGLDIVHDAFGMPMTKQYKDKLQEDKKGYASISKENISKYAGDYIFLSKPSYGKFDFEKTHTWQNIEAVKKGHVISYKAEDYWFTDPITLEHLRSKLKKEILNKSH
>NZ_CP039448.1|WP_029625651.1|2081613_2082081_-|hypothetical-protein
MKLIKSQFNIITIIISAVLTLIICHYKFLINLEDIKNALSSIITLASVNFALYGVTLSIIAGIHERAIIKKLLRNGSKSKKELEDNDSKVFYSTLFSIIFIIVFQMLYTTITSNIFSLTIFIFLSINSIILTIYYTQNYFKQISKALFDHSKFNE
>NZ_CP039448.1|WP_029625650.1|2082093_2083107_-|hypothetical-protein
MTEKKKKLVTFNIFRPTLLEYSGINRKNQERFDFNILLEYIKDQSKNFSILYKNEELAIYSIVKENLDEGLFHIRIVKYRKYDVPNAYTRLDATNININDGENDFLLPDHNEEEIPLSDNTSIGESISILYDSITNTFVIQSNLHCTTTRGIITLFDSIHSKMLSENLENKEENIEKGTEYQFHLAIIPPKKVFEKVNDFDYITEVEFVYEDNDMQDDVADILGVNNDVKAGKIQARYHIDTSKDKKKSLNKSYIDKILKLFKNDKTKFKKLDLKGRNNEESNIDLVELINARLYFQHSFTYTVEKPYLDHESVYYEMEMKYLGKEGKGDYRSKANY
>NZ_CP039448.1|WP_001293084.1|2083493_2084063_-|terminase-small-subunit
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELIEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEELDKAVQDVSNANPNHPVIVDDIPLED
>NZ_CP039448.1|WP_078065371.1|2084059_2084272_-|pathogenicity-island-family-protein
MTDDNVDDHIIKNHLEMIVDRVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYETLLDKIVEVIE
>NZ_CP039448.1|WP_000771371.1|2084403_2084931_-|spore-coat-protein
MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSISNMVLLKTVLNHYTEKEQKQVVKYMRSNGRYKPYSVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSHVKVV
>NZ_CP039448.1|WP_029625649.1|2084983_2085637_-|hypothetical-protein
MTTTTITGDTWDVYFNDRRYRNLLGDFEDLITETKSLIRQGYKMDVIKNKMDNKALSLQSKFKELGQILLDEHEEKIVEIQQKEKESSYENPQVEMLKRQDIEAKVNLIDAEELFNLVYNANPKTTNVYELNIYKKAIESRLTEDENVRLKPYFDVLVEKVIYPYRNNEEYQKLEYNYNVLRQFGLQNNGQPVIKDNDGDIEIINIQSKYNEVFRNA
>NZ_CP039448.1|WP_001190614.1|2085667_2086009_-|hypothetical-protein
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSMKRYEALKRIEV

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Crispr_ID: NZ_CP039448_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_9

2091978-2092066

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_9

>merge|NZ_CP039448|9|2091978-2092066|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>NZ_CP039448|9|9|2091978-2092066|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000197629.1\|2096212_2096956_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP039448.1\|WP_001059599.1\|2087452_2087809_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000153640.1\|2091741_2091960_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP039448.1\|WP_000240638.1\|2094061_2095678_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP039448.1\|WP_000867953.1\|2099363_2100149_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP039448.1\|WP_001105712.1\|2101117_2101687_+\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_CP039448.1\|WP_001002722.1\|2089433_2090303_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214926
NZ_CP039448.1\|WP_000151864.1\|2088051_2089422_-\|DNA-primase	unknown	unknown	gnl\|CDD\|273716
NZ_CP039448.1\|WP_001823225.1\|2100747_2100882_-\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP039448.1\|WP_001103965.1\|2090367_2090694_-\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_CP039448.1\|WP_000522383.1\|2098376_2099003_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP039448.1\|WP_001003076.1\|2087187_2087451_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000620857.1\|2092132_2092807_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP039448.1\|WP_000917289.1\|2095753_2096038_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP039448.1\|WP_000403839.1\|2090694_2091078_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000481967.1\|2091419_2091737_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP039448.1\|WP_000120338.1\|2096980_2098180_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
NZ_CP039448.1\|WP_048667709.1\|2091267_2091423_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001231376.1\|2091079_2091283_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_048667711.1\|2092820_2093993_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000197629.1\|2096212_2096956_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.12966e-11
NZ_CP039448.1\|WP_000153640.1\|2091741_2091960_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NZ_CP039448.1\|WP_000240638.1\|2094061_2095678_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP039448.1\|WP_000867953.1\|2099363_2100149_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.11308e-126
NZ_CP039448.1\|WP_001105712.1\|2101117_2101687_+\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	1.73876e-47
NZ_CP039448.1\|WP_000481967.1\|2091419_2091737_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_CP039448.1\|WP_000917289.1\|2095753_2096038_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NZ_CP039448.1\|WP_001823225.1\|2100747_2100882_-\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	4.75617e-14
NZ_CP039448.1\|WP_001103965.1\|2090367_2090694_-\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	3.47781e-22
NZ_CP039448.1\|WP_000522383.1\|2098376_2099003_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	4.41942e-115
NZ_CP039448.1\|WP_000620857.1\|2092132_2092807_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NZ_CP039448.1\|WP_000151864.1\|2088051_2089422_-\|DNA-primase	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	4.45218e-60
NZ_CP039448.1\|WP_000120338.1\|2096980_2098180_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	1.18035e-10
NZ_CP039448.1\|WP_001002722.1\|2089433_2090303_-\|hypothetical-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	2.15847e-16
NZ_CP039448.1\|WP_048667711.1\|2092820_2093993_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.29619e-47

>NZ_CP039448.1|WP_000153640.1|2091741_2091960_-|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_CP039448.1|WP_000481967.1|2091419_2091737_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_CP039448.1|WP_048667709.1|2091267_2091423_-|hypothetical-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYGMMVTYGFNLTGEITTCENK
>NZ_CP039448.1|WP_001231376.1|2091079_2091283_-|hypothetical-protein
MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEQYFPDVSKDVQVACLEMDLSKITEIKNKKKVGS
>NZ_CP039448.1|WP_000403839.1|2090694_2091078_-|hypothetical-protein
MEIKQKYQLSKVVKILEVVLYEEDKFQSDKDYHYQDKALYEYALKLVHNGLFNILAELDFEDEAFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGHVIGMLEWALDYIAGNIEVEEL
>NZ_CP039448.1|WP_001103965.1|2090367_2090694_-|DUF1474-family-protein
MNWEINDLFSDLKLLKDRFEDLKDNHGWHFEELYPHEPNHNLNKDELIREGASYHERRIHNNQMFDLFHLYIEQFDKIIEKFHEIEKASSENFGEESDDAKNSIKVAE
>NZ_CP039448.1|WP_001002722.1|2089433_2090303_-|hypothetical-protein
MNEIKLEYDTHVSVVHYESLDSRSFNSFSKPKWSKLVNKLSVPIEANYKYARGVAIYGDMKDDTDENGNEYKKYRKDENVIYRDVLVLDYDDIPKLRILHDAITETLKGVSWMYHTTFNHRTESPRVRLYIALNEHISADEYRKYTKVLESKIGHPVDEGSYQPSRAMALPVKKSNDSIYIFKYNDAPILSVETLEEWSKELKSQYKESNKFKYPKRRDNEFWKSIAFGVSTGNRNQMLTSLIGVLLNRRVPDPLVYAYCFMWNENCNPPLNSREFNATFESIYKREHR
>NZ_CP039448.1|WP_000151864.1|2088051_2089422_-|DNA-primase
MTIFPDFLENKTMFDEKDFFDGNKFKFYEFALFLYEEYHGCYIDNRPHVFTGKKYEPLNIDVVRKITIKYIPSLREQQNKEVFQKLKTLCLGNHQEQCPARYIGLKNGIYDTVEERLNPFSPQYYITNIIDVDFDKGAQSDLIERFIKDISNEDEEVEQLIYEMIGYGLYRDNFLQVAFFYYSPGGNGKTTLLKLLHHFYNPENTTALSFNDLNDKFKPANLQGKLVNIADDIDPNRIKDTGNFKIIVTGNYITLEFKGQDAFEFKPYVKLIFASNELPMSNDKSEGFYRRMVIIPMLRKFGKGGQKKDPMLLNKLITPHNMSALLNLALKGLKRTLENNEIIEPKIARKTKEEYQFENNPVLQFIEDATDKDYRQLPVVEGRNTDKAYEIYQIWCVNNGYHHLNKFNFSKELAKIGYKTVSYYSRVEEKSKRFYKKENTINIYDVDGSILKKLTE
>NZ_CP039448.1|WP_001059599.1|2087452_2087809_-|hypothetical-protein
MNNIKGELVNYIKNNAGTSFVEIEKVFDENAFDYKGQGAYTSAVNNNIVYWYGWNKQAFNLVSDLVNDGVIEMNICESIIYIVDGKGLNFPILKSDDVDTYHWLPVTFTISKKEMECV
>NZ_CP039448.1|WP_001003076.1|2087187_2087451_-|hypothetical-protein
MNEKHNIFNRFGRNTSIQTVAVKDTYFIEYRKGDEIKYFPIELATVVKALNIDLHDSDTVSNYENGPKFDIKKLNLYTGDMDQIGDE
>NZ_CP039448.1|WP_000620857.1|2092132_2092807_+|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NZ_CP039448.1|WP_048667711.1|2092820_2093993_+|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIYKKFLEKDELFQFLEIAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKTDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_CP039448.1|WP_000240638.1|2094061_2095678_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNIYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_CP039448.1|WP_000917289.1|2095753_2096038_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP039448.1|WP_000197629.1|2096212_2096956_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEHKKYIIPWALLGFALVMIYQMVVSIVYTQIFGTQQTSPNTERLIVIARKIPLFIFFVSIVGPLLEEYVFRKVIFGELFNAIKGNRIVAFAIATTVSSLIFALAHNDYKFIPIYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP039448.1|WP_000120338.1|2096980_2098180_-|hypothetical-protein
MSYHWFTKMLLSTSILILSSSSLGLATDTVEAKDNLNGEKPTTNLNHNVTSPSVNSEINNNETGTPPESNQTGNEGTDSNSRDANPDSNNVKPDSNNQNPSPDSKPDPNNPNPVPNPKPDPDKPKPNPEPKPDPDNPKPKPDPKPDPKPDPDNPKPKPDPKPDPDKPKPNPNPSPDPNQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP039448.1|WP_000522383.1|2098376_2099003_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKSFNPVEDRFVIKK
>NZ_CP039448.1|WP_000867953.1|2099363_2100149_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNDEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP039448.1|WP_001823225.1|2100747_2100882_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTISDLVKWIIDTVNKFTKK
>NZ_CP039448.1|WP_001105712.1|2101117_2101687_+|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTLAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESILLFILLPLVILNFHINPLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTFFIITLIIKEPFAQFIQLGIIIEAITLLPIFFIKEDLK

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Crispr_ID: NZ_CP039448_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_10

2339372-2339456

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTATGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_10

>merge|NZ_CP039448|10|2339372-2339456|CRISPRCasFinder
CCAACTTGCACATTATTGTATGCTGACTTTTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_CP039448|10|10|2339372-2339456|CRISPRCasFinder
CCAACTTGCACATTATTGTATGCTGACTTT	TGTCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000051210.1\|2329879_2330044_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000602934.1\|2341980_2342466_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP039448.1\|WP_001161085.1\|2330288_2330606_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_031844964.1\|2339122_2339293_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000600972.1\|2335973_2336738_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP039448.1\|WP_001824308.1\|2339633_2340656_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP039448.1\|WP_000592326.1\|2330792_2333960_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP039448.1\|WP_000866974.1\|2341281_2341515_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP039448.1\|WP_000913006.1\|2345990_2346596_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP039448.1\|WP_000184418.1\|2337333_2338545_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP039448.1\|WP_000076924.1\|2344817_2345822_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP039448.1\|WP_000134534.1\|2343784_2344279_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP039448.1\|WP_000503820.1\|2344280_2344787_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP039448.1\|WP_000951066.1\|2336900_2337341_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP039448.1\|WP_000066900.1\|2338646_2338997_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP039448.1\|WP_031844963.1\|2335730_2335982_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000643988.1\|2340675_2341275_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP039448.1\|WP_000808500.1\|2341520_2341967_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP039448.1\|WP_000259720.1\|2342462_2343722_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP039448.1\|WP_000413855.1\|2334076_2335342_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000602934.1\|2341980_2342466_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	1.17898e-50
NZ_CP039448.1\|WP_000808500.1\|2341520_2341967_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP039448.1\|WP_000413855.1\|2334076_2335342_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	8.95714e-143
NZ_CP039448.1\|WP_000600972.1\|2335973_2336738_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	2.21672e-37
NZ_CP039448.1\|WP_001824308.1\|2339633_2340656_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.93513e-164
NZ_CP039448.1\|WP_000643988.1\|2340675_2341275_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP039448.1\|WP_000913006.1\|2345990_2346596_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.03488e-114
NZ_CP039448.1\|WP_000503820.1\|2344280_2344787_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
NZ_CP039448.1\|WP_000076924.1\|2344817_2345822_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	1.97231e-131
NZ_CP039448.1\|WP_000951066.1\|2336900_2337341_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.06862e-14
NZ_CP039448.1\|WP_000066900.1\|2338646_2338997_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP039448.1\|WP_000866974.1\|2341281_2341515_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.33137e-25
NZ_CP039448.1\|WP_000592326.1\|2330792_2333960_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP039448.1\|WP_000134534.1\|2343784_2344279_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.70933e-97
NZ_CP039448.1\|WP_000259720.1\|2342462_2343722_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.25944e-158
NZ_CP039448.1\|WP_000184418.1\|2337333_2338545_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.58324e-72

>NZ_CP039448.1|WP_031844964.1|2339122_2339293_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP039448.1|WP_000066900.1|2338646_2338997_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP039448.1|WP_000184418.1|2337333_2338545_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDRSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAINLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP039448.1|WP_000951066.1|2336900_2337341_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKYQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP039448.1|WP_000600972.1|2335973_2336738_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIETVKNKLQSEQVEVVGPIQMERDTHKDGKAKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP039448.1|WP_031844963.1|2335730_2335982_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNTLTILSIVLAIIHMGILAHSTYVYLY
>NZ_CP039448.1|WP_000413855.1|2334076_2335342_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP039448.1|WP_000592326.1|2330792_2333960_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSVQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGGNLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQYQEGLGVVSTTYKKALHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATMVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP039448.1|WP_001161085.1|2330288_2330606_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP039448.1|WP_000051210.1|2329879_2330044_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP039448.1|WP_001824308.1|2339633_2340656_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLNVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEEHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP039448.1|WP_000643988.1|2340675_2341275_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP039448.1|WP_000866974.1|2341281_2341515_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQGLTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP039448.1|WP_000808500.1|2341520_2341967_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP039448.1|WP_000602934.1|2341980_2342466_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP039448.1|WP_000259720.1|2342462_2343722_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKTVKAKVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP039448.1|WP_000134534.1|2343784_2344279_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NZ_CP039448.1|WP_000503820.1|2344280_2344787_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP039448.1|WP_000076924.1|2344817_2345822_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSACTTCGDIPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP039448.1|WP_000913006.1|2345990_2346596_-|ATP-binding-cassette-domain-containing-protein
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: NZ_CP039448_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_11

2493760-2493852

Orphan

Consensus_repeat	Method
TTCTTCAAATTTATTTGTTAGAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_11

>merge|NZ_CP039448|11|2493760-2493852|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAGGCTTATGCAGTTGACGTTTTACGTCCTACTACGTTCCTTTGTCTTCTTCAAATTTATTTGTTAGAAAG

>NZ_CP039448|11|11|2493760-2493852|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAG	GCTTATGCAGTTGACGTTTTACGTCCTACTACGTTCCTTTGTC
TTCTTCAAATTTATTTGTTAGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_071665646.1\|2495731_2495914_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000200957.1\|2499523_2499991_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377623
NZ_CP039448.1\|WP_000479576.1\|2488200_2488920_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP039448.1\|WP_000162810.1\|2484890_2485490_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NZ_CP039448.1\|WP_149569703.1\|2487472_2488204_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP039448.1\|WP_000783428.1\|2498494_2499472_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NZ_CP039448.1\|WP_000819839.1\|2485508_2485871_-\|DUF4467-domain-containing-protein	unknown	unknown	gnl\|CDD\|291399
NZ_CP039448.1\|WP_001046638.1\|2501797_2502805_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_CP039448.1\|WP_000825921.1\|2488900_2489680_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270429
NZ_CP039448.1\|WP_014532694.1\|2494056_2494152_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000038954.1\|2489800_2491240_-\|multidrug-efflux-MFS-transporter-MdeA	unknown	unknown	gnl\|CDD\|129794
NZ_CP039448.1\|WP_000792557.1\|2494246_2495557_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|288473
NZ_CP039448.1\|WP_000594519.1\|2496048_2496978_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	unknown	unknown	gnl\|CDD\|369625
NZ_CP039448.1\|WP_000971541.1\|2500704_2501820_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NZ_CP039448.1\|WP_000019124.1\|2492683_2493550_-\|cation-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP039448.1\|WP_000762708.1\|2491413_2491518_+\|putative-metal-homeostasis-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_001125208.1\|2491671_2492358_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518
NZ_CP039448.1\|WP_000286874.1\|2500001_2500694_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_CP039448.1\|WP_001012236.1\|2486125_2487376_+\|FemA/FemB-family-glycyltransferase-FmhA	unknown	unknown	gnl\|CDD\|367067
NZ_CP039448.1\|WP_000916705.1\|2497545_2498493_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	unknown	unknown	gnl\|CDD\|369625

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000200957.1\|2499523_2499991_-\|hypothetical-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00179425
NZ_CP039448.1\|WP_000479576.1\|2488200_2488920_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.98247e-78
NZ_CP039448.1\|WP_000162810.1\|2484890_2485490_-\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	1.74649e-30
NZ_CP039448.1\|WP_149569703.1\|2487472_2488204_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.1649e-142
NZ_CP039448.1\|WP_000783428.1\|2498494_2499472_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
NZ_CP039448.1\|WP_000819839.1\|2485508_2485871_-\|DUF4467-domain-containing-protein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	2.57351e-31
NZ_CP039448.1\|WP_001046638.1\|2501797_2502805_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP039448.1\|WP_000825921.1\|2488900_2489680_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.11829e-100
NZ_CP039448.1\|WP_000916705.1\|2497545_2498493_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	8.96448e-91
NZ_CP039448.1\|WP_000038954.1\|2489800_2491240_-\|multidrug-efflux-MFS-transporter-MdeA	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.87495e-92
NZ_CP039448.1\|WP_000792557.1\|2494246_2495557_+\|hypothetical-protein	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	1.40953e-27
NZ_CP039448.1\|WP_000594519.1\|2496048_2496978_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	4.31899e-97
NZ_CP039448.1\|WP_000971541.1\|2500704_2501820_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	8.76662e-139
NZ_CP039448.1\|WP_000019124.1\|2492683_2493550_-\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	6.59628e-89
NZ_CP039448.1\|WP_001125208.1\|2491671_2492358_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167
NZ_CP039448.1\|WP_000286874.1\|2500001_2500694_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	3.38132e-130
NZ_CP039448.1\|WP_001012236.1\|2486125_2487376_+\|FemA/FemB-family-glycyltransferase-FmhA	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0

>NZ_CP039448.1|WP_000019124.1|2492683_2493550_-|cation-transporter
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNAITIIVSLISGLIMLIVFAVNQSLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQKVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>NZ_CP039448.1|WP_001125208.1|2491671_2492358_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>NZ_CP039448.1|WP_000762708.1|2491413_2491518_+|putative-metal-homeostasis-protein
MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK
>NZ_CP039448.1|WP_000038954.1|2489800_2491240_-|multidrug-efflux-MFS-transporter-MdeA
MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGIVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILAHASKNFSPTMSDYNGMNKIDMMNQIKVDTMLHGYHAGFLFALLITVVSFFCSFMLQGKKKEVDSRQ
>NZ_CP039448.1|WP_000825921.1|2488900_2489680_-|transporter-substrate-binding-domain-containing-protein
MKRLLFVMIAFVFILAACGNNSSKDKEANKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSRSAFAFSKKADDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>NZ_CP039448.1|WP_000479576.1|2488200_2488920_-|amino-acid-ABC-transporter-permease
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>NZ_CP039448.1|WP_149569703.1|2487472_2488204_-|ATP-binding-cassette-domain-containing-protein
MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEARGKSLELLEKVGLTLVKDQRPYALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEMFNRPKTEELRRFLNVINEE
>NZ_CP039448.1|WP_001012236.1|2486125_2487376_+|FemA/FemB-family-glycyltransferase-FmhA
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEENPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVQTYLNHKRR
>NZ_CP039448.1|WP_000819839.1|2485508_2485871_-|DUF4467-domain-containing-protein
MKRFVAMVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDSRRYYQQHDADYHEENMTN
>NZ_CP039448.1|WP_000162810.1|2484890_2485490_-|DsbA-family-protein
MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKCPYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>NZ_CP039448.1|WP_014532694.1|2494056_2494152_-|hypothetical-protein
MLTNRLTSVNYVKKRLIQNIQRILSKEVLYG
>NZ_CP039448.1|WP_000792557.1|2494246_2495557_+|hypothetical-protein
MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYTDKYFKYKGTIDKTVLSVFGNGYKSYIQPLKVEDQKNYVSKSYAQVRNYVTETLNTGKVLYAFYQNPNVVKAAITTAETAASIKNIFSSFTSFFK
>NZ_CP039448.1|WP_071665646.1|2495731_2495914_-|hypothetical-protein
MMFLHYVMFKRFIGRRRLYSYITMFCKSYSIKLSFNYGACSGRGIDCAIVCENLKLIKLR
>NZ_CP039448.1|WP_000594519.1|2496048_2496978_+|bi-component-gamma-hemolysin-HlgAB-subunit-A
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>NZ_CP039448.1|WP_000916705.1|2497545_2498493_+|bi-component-gamma-hemolysin-HlgCB-subunit-C
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKNTNHIKSMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSDLPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRIHNAFVNRNYTVKYEVNWKTHEIKVKGQN
>NZ_CP039448.1|WP_000783428.1|2498494_2499472_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NZ_CP039448.1|WP_000200957.1|2499523_2499991_-|hypothetical-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPVALLILAFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLILASVLGSLISRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_CP039448.1|WP_000286874.1|2500001_2500694_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYIKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYETV
>NZ_CP039448.1|WP_000971541.1|2500704_2501820_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAECPNQNIQKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDVDRLFEILHQED
>NZ_CP039448.1|WP_001046638.1|2501797_2502805_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKEKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN

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Crispr_ID: NZ_CP039448_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP039448_12

2850917-2851002

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP039448_12

>merge|NZ_CP039448|12|2850917-2851002|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_CP039448|12|12|2850917-2851002|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP039448.1\|WP_000672036.1\|2848146_2848338_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NZ_CP039448.1\|WP_000742837.1\|2851302_2852142_-\|nucleoid-occlusion-protein	unknown	unknown	gnl\|CDD\|275105
NZ_CP039448.1\|WP_000154165.1\|2843673_2844432_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	unknown	unknown	gnl\|CDD\|224059
NZ_CP039448.1\|WP_000240855.1\|2856844_2856982_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NZ_CP039448.1\|WP_001054123.1\|2849056_2849626_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP039448.1\|WP_001059079.1\|2848729_2848930_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP039448.1\|WP_000215588.1\|2852184_2852904_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NZ_CP039448.1\|WP_000672028.1\|2846394_2846586_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NZ_CP039448.1\|WP_000410770.1\|2842871_2843384_-\|HdeD-family-acid-resistance-protein	unknown	unknown	gnl\|CDD\|225786
NZ_CP039448.1\|WP_000779135.1\|2849876_2850272_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NZ_CP039448.1\|WP_000491384.1\|2850339_2850693_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NZ_CP039448.1\|WP_000586238.1\|2847192_2847690_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP039448.1\|WP_000362507.1\|2854847_2856227_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP039448.1\|WP_000249657.1\|2852903_2854781_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NZ_CP039448.1\|WP_001789343.1\|2856370_2856724_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
NZ_CP039448.1\|WP_000143679.1\|2844421_2846302_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	unknown	unknown	gnl\|CDD\|376899

Protein	Function_ID	Function_description	E-value
NZ_CP039448.1\|WP_000362507.1\|2854847_2856227_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP039448.1\|WP_000742837.1\|2851302_2852142_-\|nucleoid-occlusion-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.327e-113
NZ_CP039448.1\|WP_000154165.1\|2843673_2844432_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.25186e-109
NZ_CP039448.1\|WP_000240855.1\|2856844_2856982_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
NZ_CP039448.1\|WP_001054123.1\|2849056_2849626_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.69728e-16
NZ_CP039448.1\|WP_001059079.1\|2848729_2848930_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.4289e-30
NZ_CP039448.1\|WP_000215588.1\|2852184_2852904_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.12556e-96
NZ_CP039448.1\|WP_000410770.1\|2842871_2843384_-\|HdeD-family-acid-resistance-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	3.26175e-22
NZ_CP039448.1\|WP_000779135.1\|2849876_2850272_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	6.39285e-39
NZ_CP039448.1\|WP_000491384.1\|2850339_2850693_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.88155e-38
NZ_CP039448.1\|WP_000249657.1\|2852903_2854781_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_CP039448.1\|WP_001789343.1\|2856370_2856724_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	3.11548e-51
NZ_CP039448.1\|WP_000143679.1\|2844421_2846302_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.10596e-06

>NZ_CP039448.1|WP_000491384.1|2850339_2850693_-|DUF3147-family-protein
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYINHKGYRKGAIFTVVCWFVISLAIFSIRHL
>NZ_CP039448.1|WP_000779135.1|2849876_2850272_-|DUF3147-family-protein
MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGLLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKTNSK
>NZ_CP039448.1|WP_001054123.1|2849056_2849626_-|helix-turn-helix-transcriptional-regulator
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWAYVMIIFMTLAAILTGPLIVYWNWAWGITVMVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTSVLSFIAFVGAIILVALISMYLANKFL
>NZ_CP039448.1|WP_001059079.1|2848729_2848930_+|cold-shock-protein
MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEGQKVTFEITEGQRGDQAVNVQTV
>NZ_CP039448.1|WP_000672036.1|2848146_2848338_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSVVTTPIIGIPVGLLGGAYYLKRREEKGK
>NZ_CP039448.1|WP_000586238.1|2847192_2847690_-|hypothetical-protein
MIINLETQQIHFDLEHETPYFQSPEKNRIRLDIDVLNKKQISNIINVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSTDEKYVIATIKNIKNKDLIDYSLYIKKGLVEPFIVFYNQENIFYISNTVIDIISVSKDTLGYIKSEFNDHCASPY
>NZ_CP039448.1|WP_000672028.1|2846394_2846586_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSSVTTPIIGIPAGLLGGAYYLKRREEKGK
>NZ_CP039448.1|WP_000143679.1|2844421_2846302_+|peptide-resistance-ABC-transporter-permease-subunit-VraE
MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTILMLIIAYILILFQSSLFLKRRSILSMMKDSIKTDVTTAKVTTAEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLISMAPNEFNVVASQDAQQFESKLSQQHITFTKNYYETITVNNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNIINIHLNKDLVVKGTKNETFRVTQEDKGKVYPLNLSFNSPVVEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKEKAQAIAKQFGDKVITYDDMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>NZ_CP039448.1|WP_000154165.1|2843673_2844432_+|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYTSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>NZ_CP039448.1|WP_000410770.1|2842871_2843384_-|HdeD-family-acid-resistance-protein
MEKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLFVLINGVIQIVYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFWFIFSSIAGLFTFSGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFVFVGVIYVVDALA
>NZ_CP039448.1|WP_000742837.1|2851302_2852142_-|nucleoid-occlusion-protein
MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR
>NZ_CP039448.1|WP_000215588.1|2852184_2852904_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>NZ_CP039448.1|WP_000249657.1|2852903_2854781_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>NZ_CP039448.1|WP_000362507.1|2854847_2856227_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINHLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>NZ_CP039448.1|WP_001789343.1|2856370_2856724_-|ribonuclease-P-protein-component
MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>NZ_CP039448.1|WP_000240855.1|2856844_2856982_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	614495-614520	0	1.0
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	1190126-1190151	0	1.0
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	1327135-1327160	0	1.0
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	813776-813794	1	0.947
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	822945-822963	1	0.947
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	1327202-1327220	1	0.947
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	1327260-1327278	1	0.947
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	2018027-2018045	1	0.947
NZ_CP039448_10	10.1\|2339402\|25\|NZ_CP039448\|CRISPRCasFinder	2339402-2339426	25	NZ_CP039448.1	1190012-1190036	1	0.96
NZ_CP039448_10	10.1\|2339402\|25\|NZ_CP039448\|CRISPRCasFinder	2339402-2339426	25	NZ_CP039448.1	1912209-1912233	1	0.96
NZ_CP039448_10	10.1\|2339402\|25\|NZ_CP039448\|CRISPRCasFinder	2339402-2339426	25	NZ_CP039448.1	2339458-2339482	1	0.96
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	776822-776847	1	0.962
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	776878-776903	1	0.962
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	1883362-1883387	1	0.962
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	2373675-2373700	1	0.962
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	822821-822846	1	0.962
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	2066299-2066324	1	0.962
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	2256997-2257022	1	0.962
NZ_CP039448_2	2.1\|767389\|30\|NZ_CP039448\|CRISPRCasFinder	767389-767418	30	NZ_CP039448.1	808431-808460	2	0.933
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	184006-184024	2	0.895
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	614436-614454	2	0.895
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	966944-966962	2	0.895
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	1185875-1185893	2	0.895
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	1399028-1399046	2	0.895
NZ_CP039448_3	3.2\|987235\|19\|NZ_CP039448\|PILER-CR	987235-987253	19	NZ_CP039448.1	1737813-1737831	2	0.895
NZ_CP039448_10	10.1\|2339402\|25\|NZ_CP039448\|CRISPRCasFinder	2339402-2339426	25	NZ_CP039448.1	1189956-1189980	2	0.92
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	2177657-2177682	2	0.923
NZ_CP039448_12	12.1\|2850947\|26\|NZ_CP039448\|CRISPRCasFinder	2850947-2850972	26	NZ_CP039448.1	2177995-2178020	2	0.923

1. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 614495-614520, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

2. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 1190126-1190151, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

3. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 1327135-1327160, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

4. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 813776-813794, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

5. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 822945-822963, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacccc	Protospacer
****************.**

6. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 1327202-1327220, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

7. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 1327260-1327278, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

8. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 2018027-2018045, mismatch: 1, identity: 0.947

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccacacc	Protospacer
**************** **

9. spacer 10.1|2339402|25|NZ_CP039448|CRISPRCasFinder matches to position: 1190012-1190036, mismatch: 1, identity: 0.96

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgccagcttctgtgttggggccccg	Protospacer
**.**********************

10. spacer 10.1|2339402|25|NZ_CP039448|CRISPRCasFinder matches to position: 1912209-1912233, mismatch: 1, identity: 0.96

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctatgttggggccccg	Protospacer
***********.*************

11. spacer 10.1|2339402|25|NZ_CP039448|CRISPRCasFinder matches to position: 2339458-2339482, mismatch: 1, identity: 0.96

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctatgttggggccccg	Protospacer
***********.*************

12. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 776822-776847, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

13. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 776878-776903, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

14. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 1883362-1883387, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagctactatgttggggccccg	Protospacer
********* ****************

15. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 2373675-2373700, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

16. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 822821-822846, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

17. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 2066299-2066324, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgacagcttctatgttggggccccg	Protospacer
*** **********************

18. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 2256997-2257022, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

19. spacer 2.1|767389|30|NZ_CP039448|CRISPRCasFinder matches to position: 808431-808460, mismatch: 2, identity: 0.933

cagagaaattggaacgccaatttctacagg	CRISPR spacer
caaagaaattggaacaccaatttctacagg	Protospacer
**.************.**************

20. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 184006-184024, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccccacc	Protospacer
************** * **

21. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 614436-614454, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctatgttggggcccacacc	Protospacer
**.************* **

22. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 966944-966962, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggcccgcccc	Protospacer
**************.*.**

23. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 1185875-1185893, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctatgttggggcccacccc	Protospacer
**.*************.**

24. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 1399028-1399046, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggagcccacccc	Protospacer
*********.******.**

25. spacer 3.2|987235|19|NZ_CP039448|PILER-CR matches to position: 1737813-1737831, mismatch: 2, identity: 0.895

ctgtgttggggcccactcc	CRISPR spacer
ctgtgttggggccccatcc	Protospacer
**************  ***

26. spacer 10.1|2339402|25|NZ_CP039448|CRISPRCasFinder matches to position: 1189956-1189980, mismatch: 2, identity: 0.92

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgccagcttctatgttggggccccg	Protospacer
**.********.*************

27. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 2177657-2177682, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtcttggggccccg	Protospacer
************.* ***********

28. spacer 12.1|2850947|26|NZ_CP039448|CRISPRCasFinder matches to position: 2177995-2178020, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttttgtgttggggccccg	Protospacer
**********.*.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP039448_1	1.1\|650647\|30\|NZ_CP039448\|CRISPRCasFinder	650647-650676	30	NZ_CP023312	Vibrio anguillarum strain VIB12 isolate Sea bass plasmid p292, complete sequence	270977-271006	7	0.767
NZ_CP039448_2	2.1\|767389\|30\|NZ_CP039448\|CRISPRCasFinder	767389-767418	30	KC139649	Salmonella phage FSL SP-069 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, hypothetical proteins, NinH, head morphogenesis protein, hypothetical proteins, capsid related protein, hypothetical proteins, enolase-like protein, hypothetical proteins, tail fiber, hypothetical protein, putative endolysin, hypothetical proteins, and DNA polymerase genes, complete cds	9669-9698	9	0.7
NZ_CP039448_2	2.1\|767389\|30\|NZ_CP039448\|CRISPRCasFinder	767389-767418	30	KC139636	Salmonella phage FSL SP-062 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, and hypothetical proteins genes, complete cds	9669-9698	9	0.7
NZ_CP039448_2	2.1\|767389\|30\|NZ_CP039448\|CRISPRCasFinder	767389-767418	30	NC_025443	Salmonella phage 9NA, complete genome	7835-7864	9	0.7
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP024776	Bacillus thuringiensis LM1212 plasmid pLM8, complete sequence	3826-3857	9	0.719
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP009062	Borreliella afzelii K78 plasmid lp28-1, complete sequence	16532-16563	10	0.688
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP018749	Borreliella garinii strain CIP 103362 isolate 20047 plasmid lp28-7	15178-15209	10	0.688
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP028869	Borreliella garinii strain 20047 plasmid lp28-7, complete sequence	11910-11941	10	0.688
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP028878	Borreliella bavariensis PBi plasmid lp28-7, complete sequence	4741-4772	10	0.688
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP028879	Borreliella bavariensis PBi plasmid lp28-9, complete sequence	11876-11907	10	0.688
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP017215	Borreliella burgdorferi strain B331 plasmid B331_lp28_6, complete sequence	11994-12025	10	0.688
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_018987	Borrelia burgdorferi 297 plasmid 297_lp28-6, complete sequence	12713-12744	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_017412	Borreliella burgdorferi JD1 plasmid JD1 lp28-7, complete sequence	17252-17283	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_017419	Borreliella burgdorferi N40 plasmid N40_lp28-2, complete sequence	17030-17061	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_017408	Borreliella burgdorferi JD1 plasmid JD1 lp28-6, complete sequence	14812-14843	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_015920	Borreliella bissettii DN127 plasmid lp56, complete sequence	16601-16632	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_011779	Borreliella burgdorferi ZS7 plasmid ZS7_lp28-2, complete sequence	16934-16965	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NC_001852	Borreliella burgdorferi B31 plasmid lp28-2, complete sequence	16891-16922	15	0.531
NZ_CP039448_7	7.1\|2016599\|32\|NZ_CP039448\|CRISPRCasFinder	2016599-2016630	32	NZ_CP017219	Borreliella burgdorferi strain B331 plasmid B331_lp56, complete sequence	14876-14907	15	0.531

1. spacer 1.1|650647|30|NZ_CP039448|CRISPRCasFinder matches to NZ_CP023312 (Vibrio anguillarum strain VIB12 isolate Sea bass plasmid p292, complete sequence) position: , mismatch: 7, identity: 0.767

gttaaagaatacagttggtttgcttgcgca	CRISPR spacer
aagtaagaatacagttgctttgctcgcgcc	Protospacer
.   ************* ******.****

2. spacer 2.1|767389|30|NZ_CP039448|CRISPRCasFinder matches to KC139649 (Salmonella phage FSL SP-069 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, hypothetical proteins, deoxyuridine 5'-triphosphate nucleotidohydrolase, hypothetical proteins, NinH, head morphogenesis protein, hypothetical proteins, capsid related protein, hypothetical proteins, enolase-like protein, hypothetical proteins, tail fiber, hypothetical protein, putative endolysin, hypothetical proteins, and DNA polymerase genes, complete cds) position: , mismatch: 9, identity: 0.7

cagagaaattggaacgccaatttctacagg	CRISPR spacer
agctttaattggtacgccaatttctacatc	Protospacer
 .    ****** ***************

3. spacer 2.1|767389|30|NZ_CP039448|CRISPRCasFinder matches to KC139636 (Salmonella phage FSL SP-062 hypothetical proteins, RdgC exonuclease, hypothetical proteins, TerL, and hypothetical proteins genes, complete cds) position: , mismatch: 9, identity: 0.7

cagagaaattggaacgccaatttctacagg	CRISPR spacer
agctttaattggtacgccaatttctacatc	Protospacer
 .    ****** ***************

4. spacer 2.1|767389|30|NZ_CP039448|CRISPRCasFinder matches to NC_025443 (Salmonella phage 9NA, complete genome) position: , mismatch: 9, identity: 0.7

cagagaaattggaacgccaatttctacagg	CRISPR spacer
agctttaattggtacgccaatttctacatc	Protospacer
 .    ****** ***************

5. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP024776 (Bacillus thuringiensis LM1212 plasmid pLM8, complete sequence) position: , mismatch: 9, identity: 0.719

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
caaattaggatttcttttttcgaaatccttga	Protospacer
     ***.*****************.**. *

6. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP009062 (Borreliella afzelii K78 plasmid lp28-1, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

7. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP018749 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid lp28-7) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

8. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP028869 (Borreliella garinii strain 20047 plasmid lp28-7, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

9. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP028878 (Borreliella bavariensis PBi plasmid lp28-7, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

10. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP028879 (Borreliella bavariensis PBi plasmid lp28-9, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggaaatagaatttgttttttagaaattcttgt	Protospacer
.   .******** ****** ********.

11. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP017215 (Borreliella burgdorferi strain B331 plasmid B331_lp28_6, complete sequence) position: , mismatch: 10, identity: 0.688

acctgtagaatttcttttttcgaaattctcta	CRISPR spacer
ggcaacagaatttgttttttagaaattcttgt	Protospacer
. * ..******* ****** ********.

12. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_018987 (Borrelia burgdorferi 297 plasmid 297_lp28-6, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

13. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_017412 (Borreliella burgdorferi JD1 plasmid JD1 lp28-7, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

14. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_017419 (Borreliella burgdorferi N40 plasmid N40_lp28-2, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

15. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_017408 (Borreliella burgdorferi JD1 plasmid JD1 lp28-6, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

16. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_015920 (Borreliella bissettii DN127 plasmid lp56, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

17. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_011779 (Borreliella burgdorferi ZS7 plasmid ZS7_lp28-2, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

18. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NC_001852 (Borreliella burgdorferi B31 plasmid lp28-2, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

19. spacer 7.1|2016599|32|NZ_CP039448|CRISPRCasFinder matches to NZ_CP017219 (Borreliella burgdorferi strain B331 plasmid B331_lp56, complete sequence) position: , mismatch: 15, identity: 0.531

acctgtagaatttcttttttcgaaattctcta---	CRISPR spacer
---acaagaatttctaaaaaacaaattctgttgcc	Protospacer
      *********       ******* *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

745711 : 753531

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|745711_746767_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|746766_747453_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|747427_747901_-	DoxX family protein	NA	NA	NA	NA
WP_001093553.1\|748242_748683_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637683.1\|748962_749547_-	hypothetical protein	NA	NA	NA	NA
WP_001062976.1\|749645_750359_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|750362_750782_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|750783_751452_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604508.1\|751802_752396_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	6.8e-39	44.0
WP_001217800.1\|752379_753531_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	6.0e-23	36.1

DBSCAN-SWA_2

765512 : 780022

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663039.1\|765512_766571_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.4e-21	26.4
WP_000197262.1\|766729_767272_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_138269778.1\|767261_767474_+	hypothetical protein	NA	NA	NA	NA
WP_000429011.1\|767879_768797_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	6.2e-07	22.0
WP_031760357.1\|768889_768991_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|769068_770574_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_071665613.1\|770635_770884_-	hypothetical protein	NA	NA	NA	NA
WP_000930014.1\|770913_771414_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|771433_772300_-	DMT family transporter	NA	NA	NA	NA
WP_001790091.1\|772684_772951_+	hypothetical protein	NA	NA	NA	NA
WP_000692521.1\|773100_773499_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855509.1\|773461_775567_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000562498.1\|775684_776656_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|777155_777311_+	hypothetical protein	NA	NA	NA	NA
WP_000876317.1\|777349_778321_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	3.6e-138	78.6
WP_001245572.1\|778307_779264_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616873.1\|779260_780022_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

860589 : 929139

Staphylococcus_phage(75.0%)

head,terminase,capsid,integrase,holin,tail,portal,plate,coat

attL 870753:870769|attR 902907:902923

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571213.1\|860589_861615_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.4e-28	36.8
WP_000520233.1\|861607_862303_+	ABC transporter permease	NA	NA	NA	NA
WP_000732334.1\|862320_863142_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000266157.1\|863284_864505_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	6.4e-100	47.5
WP_000733774.1\|864592_865321_-	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	5.5e-22	31.8
WP_001033318.1\|865344_866073_-	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	1.0e-28	35.4
WP_001228759.1\|866142_866574_-	hypothetical protein	Q4ZCB6	Staphylococcus_virus	5.1e-36	56.0
WP_000281657.1\|866590_867049_-	ImmA/IrrE family metallo-endopeptidase	A0A0H4J322	Staphylococcus_phage	5.1e-66	83.0
WP_001260004.1\|867060_867393_-	helix-turn-helix transcriptional regulator	A0A1J0MFC1	Staphylococcus_phage	1.6e-37	74.5
WP_000243851.1\|867585_867849_+	helix-turn-helix transcriptional regulator	A0A2H4J9X2	uncultured_Caudovirales_phage	3.1e-36	94.8
WP_000091731.1\|867841_868114_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	9.7e-41	90.0
WP_000784875.1\|868125_868272_+	hypothetical protein	NA	NA	NA	NA
WP_001058486.1\|868264_868474_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	1.7e-29	94.2
WP_001103942.1\|868476_868797_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.3e-20	51.9
WP_001002732.1\|868860_869730_+	hypothetical protein	A0A1W6JQL5	Staphylococcus_phage	3.4e-156	92.7
WP_000390454.1\|869746_871216_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	2.9e-288	99.0
870753:870769	attL	NA	NA	NA	NA
WP_001039168.1\|871501_871864_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
WP_000998181.1\|871865_872150_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.9e-47	95.7
WP_001019764.1\|872146_872788_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	1.5e-108	91.5
WP_001190615.1\|873304_873646_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
WP_000846285.1\|873657_874236_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
WP_000448773.1\|874253_874472_+	hypothetical protein	NA	NA	NA	NA
WP_000771368.1\|874522_875050_+\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
WP_045181470.1\|875181_875394_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-31	98.6
WP_001293067.1\|875390_875960_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.0e-100	97.9
WP_000278085.1\|876267_877068_+	staphylococcal enterotoxin type B	A0A097PAT7	Streptococcus_pyogenes_phage	1.0e-53	49.4
WP_001035631.1\|877145_877703_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	1.4e-70	73.8
WP_001795626.1\|878076_878229_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	7.6e-19	98.0
WP_000139423.1\|878299_878410_+	hypothetical protein	W5R8J7	Staphylococcus_phage	1.7e-12	100.0
WP_000382163.1\|878396_878597_+	hypothetical protein	W5R9N2	Staphylococcus_phage	3.7e-29	100.0
WP_000752917.1\|879720_879915_+	CsbD family protein	NA	NA	NA	NA
WP_001183851.1\|880148_881000_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_000168845.1\|881328_882090_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3
WP_000205572.1\|882187_883495_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000807678.1\|883609_884851_+	cysteine desulfurase	Q2XUY6	environmental_halophage	8.2e-111	44.8
WP_001010508.1\|884840_885305_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_001074405.1\|885455_886853_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_001145726.1\|886920_887970_-\|integrase	site-specific integrase	A1KWY3	Staphylococcus_virus	4.5e-203	99.7
WP_000337826.1\|888082_888262_+	hypothetical protein	A0EWN7	Staphylococcus_virus	8.3e-25	100.0
WP_072472622.1\|888241_889174_-	hypothetical protein	A0EWN8	Staphylococcus_virus	3.3e-173	99.7
WP_000661437.1\|889205_889931_-	hypothetical protein	A0A0F6N4L7	Staphylococcus_phage	9.9e-125	100.0
WP_000775187.1\|889958_890633_-	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	4.9e-126	100.0
WP_001055143.1\|890649_890982_-	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	4.1e-57	100.0
WP_000108122.1\|891244_891439_+	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	1.1e-25	100.0
WP_149569682.1\|891438_892203_+	phage antirepressor Ant	R4IFK0	Staphylococcus_phage	1.4e-140	99.2
WP_001148854.1\|892219_892414_+	hypothetical protein	Q4ZDS1	Staphylococcus_virus	4.6e-21	90.5
WP_000939503.1\|892444_892588_+	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.8e-14	91.3
WP_000388992.1\|892608_893166_-	hypothetical protein	A0A2H4IYS4	uncultured_Caudovirales_phage	1.7e-47	54.5
WP_000977380.1\|893236_893458_+	hypothetical protein	A0A0F6N3I2	Staphylococcus_phage	9.6e-31	97.3
WP_000048126.1\|893450_893612_+	DUF1270 family protein	A0A2H4PQQ1	Staphylococcus_phage	3.3e-20	100.0
WP_000291089.1\|893703_893964_+	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	1.2e-43	100.0
WP_001004336.1\|893976_894513_+	hypothetical protein	A0A0F6N4M6	Staphylococcus_phage	1.4e-80	100.0
WP_000840496.1\|894513_895164_+	single-stranded DNA-binding protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
WP_001099007.1\|895160_895604_+	single-stranded DNA-binding protein	G4KNN8	Staphylococcus_phage	1.4e-76	100.0
WP_031769015.1\|895615_896290_+	phi PV83 orf 19-like protein	Q4ZD97	Staphylococcus_virus	8.4e-126	97.3
WP_000371250.1\|896395_897253_-	DUF4393 domain-containing protein	Q4ZBL8	Staphylococcus_phage	9.5e-159	100.0
WP_031769013.1\|897317_898088_+	replication protein	A0A2H4PQI2	Staphylococcus_phage	9.0e-116	99.6
WP_031769012.1\|898097_898871_+	ATP-binding protein	D2JGK5	Staphylococcus_phage	1.6e-141	98.4
WP_001123673.1\|899038_899260_+	DUF3269 family protein	A7TWN4	Staphylococcus_phage	1.3e-35	100.0
WP_000049784.1\|899270_899675_+	DUF1064 domain-containing protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
WP_001187242.1\|899679_899865_+	DUF3113 family protein	W5R8N4	Staphylococcus_phage	1.4e-27	100.0
WP_001140289.1\|899865_900237_+	hypothetical protein	A7TWN6	Staphylococcus_phage	4.0e-53	95.9
WP_001126846.1\|900237_900486_+	hypothetical protein	S4V683	Staphylococcus_phage	8.8e-41	97.6
WP_001065064.1\|900500_900752_+	DUF1024 family protein	G4KNP4	Staphylococcus_phage	1.9e-38	98.8
WP_149569683.1\|901091_901619_+	dUTPase	B2ZYX2	Staphylococcus_phage	3.1e-91	95.4
WP_029625633.1\|901655_901862_+	DUF1381 domain-containing protein	A0A2I6PDB6	Staphylococcus_phage	1.9e-25	85.3
WP_149569684.1\|901858_902032_+	transcriptional regulator	A1KX88	Staphylococcus_virus	6.4e-22	98.2
WP_000286968.1\|902032_902434_+	hypothetical protein	A0A2H4PQK5	Staphylococcus_phage	5.6e-69	100.0
WP_029647107.1\|902363_902618_-	hypothetical protein	Q4ZB48	Staphylococcus_virus	1.3e-23	83.3
WP_000594088.1\|902788_903283_+\|terminase	terminase	A0A0N9BAX3	Staphylococcus_phage	3.4e-84	100.0
902907:902923	attR	NA	NA	NA	NA
WP_001037578.1\|903275_904499_+\|terminase	PBSX family phage terminase large subunit	A0A0N9BAX9	Staphylococcus_phage	7.5e-242	100.0
WP_053507576.1\|904495_905920_+\|portal	phage portal protein	A0A0E3T9I6	Staphylococcus_phage	1.8e-271	99.8
WP_000184133.1\|905888_906842_+	hypothetical protein	A0A0N7E0U6	Staphylococcus_phage	6.6e-177	99.7
WP_000346033.1\|906843_907050_+	hypothetical protein	A0A0N9BB04	Staphylococcus_phage	3.2e-28	100.0
WP_001019219.1\|907152_907737_+	DUF4355 domain-containing protein	A0A0N7E0U8	Staphylococcus_phage	1.3e-77	100.0
WP_000235168.1\|907753_908668_+\|capsid	phage major capsid protein	A0A0H3U2U7	Staphylococcus_phage	1.2e-170	100.0
WP_000177351.1\|908828_909179_+\|head,tail	phage head-tail adapter protein	A0A0H3U2R5	Staphylococcus_phage	1.9e-60	100.0
WP_000483041.1\|909190_909526_+\|head	phage head closure protein	A0A0E3TAH8	Staphylococcus_phage	8.8e-60	100.0
WP_000270192.1\|909939_910365_+	DUF3168 domain-containing protein	Q4ZBQ9	Staphylococcus_phage	5.5e-75	100.0
WP_000057582.1\|910365_910923_+\|tail	tail protein	Q4ZBQ8	Staphylococcus_phage	8.2e-103	100.0
WP_000134337.1\|910989_911496_+	hypothetical protein	Q4ZBQ7	Staphylococcus_phage	2.7e-92	100.0
WP_000880587.1\|911540_911825_+	hypothetical protein	A0A0N7E0V9	Staphylococcus_phage	8.8e-45	100.0
WP_000379451.1\|911828_914714_+\|terminase	terminase	A1KXA6	Staphylococcus_virus	0.0e+00	99.9
WP_000560181.1\|914728_915670_+\|tail	phage tail protein	Q4ZBQ4	Staphylococcus_phage	5.2e-182	100.0
WP_001122001.1\|915680_917567_+	peptidase	Q4ZBQ3	Staphylococcus_phage	0.0e+00	100.0
WP_117434812.1\|917579_919478_+	hypothetical protein	Q4ZBX7	Staphylococcus_virus	0.0e+00	99.5
WP_029052110.1\|919477_921301_+\|plate	phage baseplate upper protein	A0A0F6N3G2	Staphylococcus_phage	0.0e+00	99.8
WP_000705921.1\|921300_921678_+	DUF2977 domain-containing protein	Q4ZBX4	Staphylococcus_virus	1.6e-54	100.0
WP_001790193.1\|921681_921855_+	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_000466769.1\|921895_922195_+	DUF2951 domain-containing protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
WP_149569685.1\|922331_924206_+	CHAP domain-containing protein	A0A2H4JB48	uncultured_Caudovirales_phage	0.0e+00	99.2
WP_072464654.1\|924218_925391_+\|plate	BppU family phage baseplate upper protein	Q4ZDT3	Staphylococcus_virus	2.4e-197	99.5
WP_017804641.1\|925395_925791_+	hypothetical protein	A0A0E3XBL9	Staphylococcus_phage	1.3e-65	97.7
WP_000354132.1\|925846_926284_+\|holin	phage holin	A0A2H4PQP0	Staphylococcus_phage	4.1e-73	100.0
WP_149569686.1\|926264_927710_+	CHAP domain-containing protein	A0A0H3U310	Staphylococcus_phage	2.6e-294	99.2
WP_000448197.1\|928099_928687_+	hypothetical protein	Q4ZBG7	Staphylococcus_virus	5.4e-97	100.0
WP_000971220.1\|928683_929139_+	hypothetical protein	B7T0L3	Staphylococcus_virus	2.7e-72	100.0

DBSCAN-SWA_4

1012949 : 1056667

Streptococcus_phage(33.33%)

tRNA,transposase,bacteriocin,holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000277723.1\|1012949_1014596_+\|transposase	IS1182-like element ISSau3 family transposase	A0ZS58	Staphylococcus_virus	1.6e-292	99.1
WP_000448937.1\|1014621_1015611_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|1015905_1016301_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217728.1\|1016671_1017391_+	adaptor protein MecA	NA	NA	NA	NA
WP_000959296.1\|1017511_1018498_+	hypothetical protein	NA	NA	NA	NA
WP_000082725.1\|1018545_1020354_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
WP_000896697.1\|1020813_1021620_-	DsbA family protein	NA	NA	NA	NA
WP_000214067.1\|1021642_1022008_-	hypothetical protein	NA	NA	NA	NA
WP_000224622.1\|1022111_1022705_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242107.1\|1022890_1023238_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|1023254_1023890_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|1023906_1024716_+	NAD kinase	NA	NA	NA	NA
WP_000669925.1\|1024712_1025567_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000062407.1\|1025587_1026973_+	magnesium transporter	NA	NA	NA	NA
WP_000395162.1\|1026982_1028827_+	sodium:proton antiporter	NA	NA	NA	NA
WP_000933195.1\|1029105_1029876_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|1030072_1031158_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570701.1\|1031499_1033068_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_000889183.1\|1033210_1033969_+	esterase family protein	NA	NA	NA	NA
WP_001060547.1\|1034134_1034860_+	hypothetical protein	NA	NA	NA	NA
WP_000355328.1\|1034861_1035713_+	hypothetical protein	NA	NA	NA	NA
WP_000600387.1\|1036447_1036957_+	hypothetical protein	NA	NA	NA	NA
WP_001824107.1\|1037069_1038278_-	MFS transporter	NA	NA	NA	NA
WP_000258650.1\|1038237_1039413_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340127.1\|1039845_1041330_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001798480.1\|1041310_1041571_+	hypothetical protein	NA	NA	NA	NA
WP_001049958.1\|1041570_1043133_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	3.2e-35	28.0
WP_000928413.1\|1043434_1044238_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_078064575.1\|1044453_1046778_+\|protease	serine protease	W5SAB9	Pithovirus	2.1e-11	27.4
WP_000021872.1\|1046794_1048153_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414178.1\|1048291_1049803_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|1050291_1050861_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|1051070_1051289_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000668820.1\|1051369_1052356_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1052554_1052731_+	YkvS family protein	NA	NA	NA	NA
WP_001033867.1\|1052745_1053348_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_057504515.1\|1053743_1055390_+\|transposase	IS1182-like element ISSau3 family transposase	A0A146ICT8	Staphylococcus_phage	9.7e-293	99.6
WP_099112139.1\|1055673_1055751_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_029656376.1\|1056400_1056667_+\|bacteriocin	bacteriocin transporter	NA	NA	NA	NA

DBSCAN-SWA_5

1090881 : 1099354

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861570.1\|1090881_1091364_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.0e-22	44.7
WP_001010401.1\|1091350_1092475_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174047.1\|1092478_1093183_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	1.4e-46	41.2
WP_000848350.1\|1093182_1093446_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1093447_1094119_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032747.1\|1094111_1096301_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.8e-140	39.7
WP_000483727.1\|1096279_1097764_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-44	31.5
WP_000030810.1\|1097756_1098785_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238670.1\|1098787_1099354_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1

DBSCAN-SWA_6

1357297 : 1362247

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001659797.1\|1357297_1357495_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
WP_078065144.1\|1358184_1358409_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-18	71.0
WP_001002343.1\|1358704_1358911_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.9e-12	56.7
WP_001788716.1\|1359606_1359717_+	hypothetical protein	NA	NA	NA	NA
WP_000006110.1\|1360145_1360331_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_000477491.1\|1360842_1360947_+	hypothetical protein	NA	NA	NA	NA
WP_000956747.1\|1361073_1361325_+	hypothetical protein	NA	NA	NA	NA
WP_001813273.1\|1361798_1362053_+	hypothetical protein	A0A1J0MF61	Staphylococcus_phage	1.4e-25	62.7
WP_000780597.1\|1362052_1362247_+	hypothetical protein	A0A1J0MG79	Staphylococcus_phage	2.8e-18	71.4

DBSCAN-SWA_7

1536286 : 1618271

106

Staphylococcus_phage(85.0%)

head,terminase,capsid,tRNA,integrase,holin,tail,protease,portal

attL 1596104:1596118|attR 1614087:1614101

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858801.1\|1536286_1537579_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.5e-54	30.0
WP_000525064.1\|1537900_1540594_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	1.1e-46	34.6
WP_000049916.1\|1540617_1541589_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361537.1\|1541575_1542778_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	5.4e-35	43.3
WP_000690024.1\|1542782_1543925_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1544182_1544500_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1544835_1545516_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000154692.1\|1545587_1546175_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000005216.1\|1546164_1546740_-	IDEAL domain-containing protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
WP_000389518.1\|1546753_1547998_-	hypothetical protein	NA	NA	NA	NA
WP_000245912.1\|1548004_1549303_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776330.1\|1549312_1550377_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269940.1\|1550402_1551569_-	chorismate synthase	A0A291AU41	Pandoravirus	2.6e-34	32.3
WP_000789522.1\|1551955_1552156_-	hypothetical protein	NA	NA	NA	NA
WP_000442477.1\|1552365_1552815_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_078062714.1\|1552906_1553851_-	heptaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774684.1\|1553867_1554593_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450555.1\|1554595_1555168_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1555598_1555871_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161742.1\|1556041_1557040_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1557056_1558367_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133960.1\|1558583_1559759_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_031844924.1\|1560014_1560206_-	hypothetical protein	NA	NA	NA	NA
WP_031844926.1\|1560322_1560427_-	hypothetical protein	NA	NA	NA	NA
WP_000644394.1\|1560469_1561129_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681761.1\|1561205_1562174_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1562288_1563275_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_001824277.1\|1563435_1563552_-	hypothetical protein	NA	NA	NA	NA
WP_000069308.1\|1563676_1565137_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902114.1\|1565289_1566669_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.2e-56	33.6
WP_001163813.1\|1566658_1567612_-	hypothetical protein	NA	NA	NA	NA
WP_001151997.1\|1567719_1567968_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186908.1\|1568073_1568619_-	ECF transporter S component	NA	NA	NA	NA
WP_000476869.1\|1569021_1569966_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476889.1\|1570023_1570929_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_061820357.1\|1571019_1571271_-	hypothetical protein	A0ZS61	Staphylococcus_virus	2.0e-24	96.7
WP_024937002.1\|1571453_1572437_-	Panton-Valentine bi-component leukocidin subunit F	A0A2I6PEU3	Staphylococcus_phage	4.0e-185	100.0
WP_000239544.1\|1572432_1573371_-	Panton-Valentine bi-component leukocidin subunit S	A0A2I6PF61	Staphylococcus_phage	1.7e-180	100.0
WP_000909204.1\|1573760_1575215_-	CHAP domain-containing protein	A0A2I6PF47	Staphylococcus_phage	7.5e-289	100.0
WP_000339141.1\|1575225_1575528_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000340977.1\|1575653_1576028_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001040259.1\|1576083_1576371_-	hypothetical protein	G4KNR2	Staphylococcus_phage	9.9e-44	100.0
WP_001153681.1\|1576417_1576570_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_000582126.1\|1576559_1580345_-	hypothetical protein	G4KNR1	Staphylococcus_phage	0.0e+00	100.0
WP_000567420.1\|1580360_1581845_-\|tail	phage tail protein	G4KNR0	Staphylococcus_phage	1.6e-299	100.0
WP_000504558.1\|1581844_1586386_-\|tail	phage tail tape measure protein	A0A2I6PE03	Staphylococcus_phage	0.0e+00	100.0
WP_001096355.1\|1586630_1586981_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_071621395.1\|1587030_1587255_-	hypothetical protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
WP_000268740.1\|1587296_1587941_-\|tail	phage tail protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1\|1587941_1588349_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114226.1\|1588345_1588750_-	hypothetical protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
WP_000755150.1\|1588746_1589109_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000150936.1\|1589092_1589377_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|1589366_1589651_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154559.1\|1589670_1590816_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
WP_000642728.1\|1590839_1591577_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025272.1\|1591560_1592748_-\|portal	phage portal protein	G4KNQ1	Staphylococcus_phage	4.6e-220	100.0
WP_000625097.1\|1592763_1594425_-\|terminase	terminase large subunit	G4KNQ0	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|1594421_1594766_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988330.1\|1594896_1595196_-	HNH endonuclease	G4KNP8	Staphylococcus_phage	4.6e-52	100.0
WP_000590122.1\|1595427_1595844_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000265043.1\|1595871_1596072_-	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
WP_001005262.1\|1596071_1596722_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
1596104:1596118	attL	NA	NA	NA	NA
WP_000501856.1\|1596880_1597045_-	transcriptional activator RinB	A0A2I6PDY4	Staphylococcus_phage	3.9e-21	100.0
WP_001125015.1\|1597032_1597233_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195782.1\|1597207_1597396_-	DUF1381 domain-containing protein	A0A2I6PDV0	Staphylococcus_phage	2.1e-26	100.0
WP_001282074.1\|1597392_1597638_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_001061834.1\|1597674_1598181_-	hypothetical protein	G4KNP5	Staphylococcus_phage	1.0e-91	100.0
WP_000454994.1\|1598357_1598639_-	hypothetical protein	A0A2I6PDX3	Staphylococcus_phage	8.5e-48	100.0
WP_001065099.1\|1598802_1599054_-	DUF1024 family protein	G4KNP4	Staphylococcus_phage	6.4e-39	100.0
WP_000131388.1\|1599068_1599311_-	hypothetical protein	A0A2I6PDU1	Staphylococcus_phage	3.9e-41	100.0
WP_000029366.1\|1599314_1599671_-	hypothetical protein	G4KNP3	Staphylococcus_phage	1.1e-60	100.0
WP_001187236.1\|1599671_1599857_-	DUF3113 family protein	A0A068A236	Staphylococcus_phage	7.8e-26	95.1
WP_000049798.1\|1599861_1600266_-	DUF1064 domain-containing protein	G4KNP2	Staphylococcus_phage	1.6e-68	100.0
WP_001123669.1\|1600275_1600497_-	DUF3269 family protein	A0A2I6PDV8	Staphylococcus_phage	1.7e-35	100.0
WP_000256594.1\|1600509_1600668_-	hypothetical protein	A0A2I6PDX0	Staphylococcus_phage	4.5e-22	98.1
WP_000803062.1\|1600661_1601441_-	ATP-binding protein	G4KNP1	Staphylococcus_phage	3.8e-146	100.0
WP_000190254.1\|1601450_1602221_-	hypothetical protein	G4KNP0	Staphylococcus_phage	6.4e-122	100.0
WP_000414755.1\|1602286_1602568_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
WP_000057262.1\|1602706_1603381_-	hypothetical protein	G4KNN9	Staphylococcus_phage	8.6e-131	100.0
WP_001099007.1\|1603392_1603836_-	single-stranded DNA-binding protein	G4KNN8	Staphylococcus_phage	1.4e-76	100.0
WP_000840496.1\|1603832_1604483_-	single-stranded DNA-binding protein	A0A0F6N3I5	Staphylococcus_phage	1.1e-119	100.0
WP_001004336.1\|1604483_1605020_-	hypothetical protein	A0A0F6N4M6	Staphylococcus_phage	1.4e-80	100.0
WP_001556704.1\|1605032_1605293_-	DUF1108 family protein	G4KNN5	Staphylococcus_phage	2.0e-43	100.0
WP_000829610.1\|1605297_1605615_-	hypothetical protein	A0A2I6PEL3	Staphylococcus_phage	3.9e-33	100.0
WP_001285954.1\|1605703_1605865_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124198.1\|1605876_1606140_-	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
WP_001037095.1\|1606169_1606388_-	hypothetical protein	A0A2I6PDV4	Staphylococcus_phage	5.0e-32	100.0
WP_001025595.1\|1606384_1606711_-	hypothetical protein	G4KNN2	Staphylococcus_phage	5.4e-54	100.0
WP_000435343.1\|1606944_1607205_-	hypothetical protein	A0A2I6PDT7	Staphylococcus_phage	3.5e-40	100.0
WP_001148617.1\|1607217_1607970_-	oxidoreductase	G4KNN1	Staphylococcus_phage	1.1e-139	100.0
WP_000801108.1\|1608030_1608258_+	hypothetical protein	A7TWL9	Staphylococcus_phage	1.7e-38	100.0
WP_000502678.1\|1608259_1608451_-	hypothetical protein	A0A2I6PDT1	Staphylococcus_phage	9.5e-27	100.0
WP_000772137.1\|1608507_1608717_+	hypothetical protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
WP_000939495.1\|1608709_1608850_-	hypothetical protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
WP_000435346.1\|1608864_1609308_-	hypothetical protein	G4KNN0	Staphylococcus_phage	2.0e-75	100.0
WP_000548578.1\|1609320_1609560_-	helix-turn-helix transcriptional regulator	G4KNM9	Staphylococcus_phage	2.3e-38	100.0
WP_000094093.1\|1609730_1610438_+	helix-turn-helix transcriptional regulator	G4KNM8	Staphylococcus_phage	7.7e-130	100.0
WP_001089804.1\|1610591_1610777_+	hypothetical protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
WP_000705240.1\|1610976_1611159_+	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_001013104.1\|1611194_1611341_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_000191466.1\|1611337_1611952_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
WP_000264751.1\|1612077_1613283_+\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
WP_001838630.1\|1613325_1615353_-	hypothetical protein	B5WZK7	Staphylococcus_phage	3.3e-109	92.5
1614087:1614101	attR	NA	NA	NA	NA
WP_001824281.1\|1615364_1616273_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000987767.1\|1616519_1618271_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	2.6e-22	33.6

DBSCAN-SWA_8

1674099 : 1682411

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1674099_1674885_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924210.1\|1675010_1675901_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	33.1
WP_001062177.1\|1675910_1677257_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683914.1\|1677370_1678471_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
WP_000624567.1\|1678473_1679151_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1679281_1680388_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217251.1\|1680611_1682411_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_9

1753055 : 1762098

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364543.1\|1753055_1753574_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.1e-28	45.8
WP_000594983.1\|1753595_1755869_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.1e-64	29.5
WP_000749798.1\|1756071_1758351_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1758625_1758886_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1758904_1760044_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019166.1\|1760066_1761092_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1761093_1762098_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_10

1888077 : 1934005

Staphylococcus_phage(94.29%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050576.1\|1888077_1894635_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.2e-290	93.2
WP_000836467.1\|1894960_1895272_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	5.3e-51	98.1
WP_001108730.1\|1895293_1897708_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025062.1\|1897999_1899181_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.2e-217	99.5
WP_000526539.1\|1899290_1900244_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_149569697.1\|1900240_1900804_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	4.6e-101	98.4
WP_000757543.1\|1900923_1901325_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266100.1\|1901897_1902725_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1902727_1902847_-	hypothetical protein	NA	NA	NA	NA
WP_071665630.1\|1902858_1903050_-	hypothetical protein	NA	NA	NA	NA
WP_001196343.1\|1902958_1903960_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	1.7e-183	98.8
WP_001008551.1\|1904081_1904546_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159028.1\|1904558_1905740_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.6e-225	99.2
WP_000493883.1\|1905750_1906383_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.4e-111	98.6
WP_000384177.1\|1906389_1907421_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	9.0e-196	98.5
WP_001261664.1\|1907913_1909416_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.1e-29	98.6
WP_000221186.1\|1909937_1910252_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.4e-51	95.2
WP_000989100.1\|1910251_1911544_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	2.2e-223	97.4
WP_000163239.1\|1911561_1911954_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.9e-72	99.2
WP_001032836.1\|1912358_1913213_-	autolysin	Q4ZCC7	Staphylococcus_virus	4.9e-38	38.1
WP_000384172.1\|1913488_1913713_-	hypothetical protein	NA	NA	NA	NA
WP_001153740.1\|1914490_1914934_+	competence protein ComK	NA	NA	NA	NA
WP_001030460.1\|1914920_1915364_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	5.4e-57	98.0
WP_025175276.1\|1915661_1916297_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_000492902.1\|1916463_1917084_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001096492.1\|1917552_1918266_-	transaldolase	M1PR54	Cyanophage	1.2e-18	34.5
WP_000091445.1\|1918523_1918826_+	hypothetical protein	NA	NA	NA	NA
WP_001200550.1\|1919081_1919447_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.2e-59	98.3
WP_000623471.1\|1919443_1919797_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453310.1\|1920046_1920880_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.3e-157	99.3
WP_000366163.1\|1921091_1922000_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933822.1\|1922124_1923318_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_149569698.1\|1923689_1925282_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.6
WP_078065176.1\|1925575_1926322_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.8e-141	98.0
WP_000672009.1\|1926326_1926800_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.6e-83	98.1
WP_000718107.1\|1926865_1927123_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778518.1\|1927119_1928121_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.9
WP_000348385.1\|1928125_1929604_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.0e-280	96.5
WP_078065177.1\|1929763_1930219_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	4.0e-79	97.9
WP_001838615.1\|1930521_1931172_+	hypothetical protein	A0A2H4PQM8	Staphylococcus_phage	4.7e-33	68.5
WP_000070638.1\|1931252_1932248_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.7e-66	92.7
WP_000669039.1\|1932323_1932950_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.8e-81	84.6
WP_000627534.1\|1932990_1933332_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	2.8e-53	93.8
WP_000414219.1\|1933432_1934005_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8

DBSCAN-SWA_11

1939559 : 1947871

Staphylococcus_phage(72.73%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001044434.1\|1939559_1940414_-	M23 family metallopeptidase	E5G070	Clostridium_phage	6.4e-06	37.9
WP_049280116.1\|1940664_1941210_-	hypothetical protein	A0A2H4PQP5	Staphylococcus_phage	1.8e-09	32.5
WP_000669789.1\|1941626_1941806_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001795394.1\|1941829_1942138_+	hypothetical protein	M9NTD8	Staphylococcus_phage	2.1e-39	100.0
WP_001791826.1\|1942116_1942377_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|1942428_1942779_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000727649.1\|1943461_1943911_+	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_020444758.1\|1944005_1944464_-	amidase	R9QTN8	Staphylococcus_phage	4.9e-85	98.7
WP_001066124.1\|1944642_1945404_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.1e-54	44.2
WP_000777467.1\|1945396_1946689_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	2.6e-14	30.8
WP_000206347.1\|1947082_1947871_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	7.0e-140	95.4

DBSCAN-SWA_12

2083493 : 2096038

Staphylococcus_phage(61.11%)

integrase,terminase,coat

attL 2078417:2078436|attR 2094060:2094079

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2078417:2078436	attL	NA	NA	NA	NA
WP_001293084.1\|2083493_2084063_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	8.7e-100	96.8
WP_078065371.1\|2084059_2084272_-	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	5.4e-31	94.3
WP_000771371.1\|2084403_2084931_-\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	1.4e-88	97.1
WP_029625649.1\|2084983_2085637_-	hypothetical protein	Q4ZE82	Staphylococcus_phage	1.7e-115	99.1
WP_001190614.1\|2085667_2086009_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.9e-58	100.0
WP_001019280.1\|2086544_2087186_-	hypothetical protein	Q4ZE67	Staphylococcus_phage	8.5e-112	94.8
WP_001003076.1\|2087187_2087451_-	hypothetical protein	NA	NA	NA	NA
WP_001059599.1\|2087452_2087809_-	hypothetical protein	A0A2H4JBD4	uncultured_Caudovirales_phage	3.0e-50	78.8
WP_000151864.1\|2088051_2089422_-	DNA primase	A0A2H4JBE3	uncultured_Caudovirales_phage	2.4e-257	95.0
WP_001002722.1\|2089433_2090303_-	hypothetical protein	A0A2H4JEH3	uncultured_Caudovirales_phage	2.2e-131	75.8
WP_001103965.1\|2090367_2090694_-	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.8e-54	98.1
WP_000403839.1\|2090694_2091078_-	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	9.7e-63	96.1
WP_001231376.1\|2091079_2091283_-	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
WP_048667709.1\|2091267_2091423_-	hypothetical protein	NA	NA	NA	NA
WP_000481967.1\|2091419_2091737_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000153640.1\|2091741_2091960_-	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000620857.1\|2092132_2092807_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_048667711.1\|2092820_2093993_+\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	7.8e-220	98.2
WP_000240638.1\|2094061_2095678_-	chaperonin GroEL	A0A240F779	uncultured_virus	2.6e-157	54.7
2094060:2094079	attR	NA	NA	NA	NA
WP_000917289.1\|2095753_2096038_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

DBSCAN-SWA_13

2695981 : 2732518

Streptococcus_phage(45.0%)

holin,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002354485.1\|2695981_2696668_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_001240982.1\|2697066_2699985_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
WP_000576156.1\|2699988_2700543_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_000085855.1\|2700761_2700893_-	hypothetical protein	E4ZFP9	Streptococcus_phage	8.2e-14	90.7
WP_001038790.1\|2700897_2701635_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_001814874.1\|2701759_2701843_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_001096887.1\|2702384_2703179_-	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_001255866.1\|2703748_2704657_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
WP_000662263.1\|2704689_2705424_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_000233000.1\|2705404_2706274_-	hypothetical protein	A0A1X9I6C9	Streptococcus_phage	6.7e-152	90.7
WP_000205227.1\|2706288_2706513_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002390960.1\|2706655_2708200_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.8e-256	88.7
WP_000323438.1\|2708219_2708636_-	recombinase	A0A2K5B2B3	Erysipelothrix_phage	1.2e-71	98.6
WP_002360685.1\|2708636_2708933_-	hypothetical protein	A0A2K5B2B2	Erysipelothrix_phage	4.6e-44	91.8
WP_000898188.1\|2708966_2709134_-	hypothetical protein	A0A2K5B2B2	Erysipelothrix_phage	2.6e-20	92.7
WP_001062586.1\|2710137_2710740_-	recombinase family protein	A0A219YA40	Aeromonas_phage	5.7e-17	38.3
WP_002354485.1\|2711240_2711927_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_096827997.1\|2712667_2713354_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	8.5e-126	98.7
WP_014363485.1\|2713401_2713749_-	hypothetical protein	NA	NA	NA	NA
WP_000161217.1\|2713764_2714841_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_014532712.1\|2715183_2715555_-	aspartate 1-decarboxylase	NA	NA	NA	NA
WP_000163745.1\|2715568_2716420_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_000860047.1\|2716412_2717231_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	NA	NA	NA	NA
WP_000953560.1\|2717303_2718164_+	oxidoreductase	NA	NA	NA	NA
WP_000186117.1\|2718249_2718954_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_000846637.1\|2719231_2720191_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_000534436.1\|2720877_2722326_+	amino acid permease	NA	NA	NA	NA
WP_000030049.1\|2722405_2723743_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	1.8e-18	26.7
WP_001237630.1\|2723996_2724413_+	hypothetical protein	NA	NA	NA	NA
WP_001031407.1\|2724535_2725426_+	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	1.2e-07	29.2
WP_001130051.1\|2725620_2727117_-	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_025174545.1\|2727412_2727742_+	hypothetical protein	NA	NA	NA	NA
WP_001172340.1\|2727801_2729400_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	5.3e-78	36.8
WP_001028780.1\|2729593_2730037_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_000011688.1\|2730316_2730529_-	hypothetical protein	NA	NA	NA	NA
WP_000066521.1\|2730808_2732518_-\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	3.8e-58	32.3

Anti-CRISPR protein detection

Acr_ID: NZ_CP039448.1|WP_000384172.1|1913488_1913713_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP039448.1|WP_000384172.1|1913488_1913713_-|hypothetical-protein

1913488_1913713_-

74 aa aa

1888077-1934005

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP039448_10	Orphan	10.1\|2339402\|25\|NZ_CP039448\|CRISPRCasFinder	2339402-2339426	25	1912209-1912233	1

1. spacer 10.1|2339402|25|NZ_CP039448|CRISPRCasFinder matches to NZ_CP039448 position: 1912209-1912233, mismatch: 1

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctatgttggggccccg	Protospacer
***********.*************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP039448

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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