CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP043503	Bacillus paralicheniformis strain A4-3 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0	0
NZ_CP043501	Bacillus paralicheniformis strain A4-3 chromosome, complete genome	3 crisprs	csa3,cas3,WYL,DinG,DEDDh	4	8	1
NZ_CP043502	Bacillus paralicheniformis strain A4-3 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043501_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043501_1

3558621-3558719

Orphan

Consensus_repeat	Method
TCAGGCAGCGATTCTTTTAGCGTT	CRISPRCasFinder

1 spacers

csa3,WYL

The CRISPR arrays of NZ_CP043501_1

>merge|NZ_CP043501|1|3558621-3558719|CRISPRCasFinder
TCAGGCAGCGATTCTTTTAGCGTTTCTACAACTGACCGCTCGACACTTTTCGTAGAGCCGGCGGCCGTCCCACTATCAGACAGCGATTCTTTTAGCGTT

>NZ_CP043501|1|1|3558621-3558719|CRISPRCasFinder
TCAGGCAGCGATTCTTTTAGCGTT	TCTACAACTGACCGCTCGACACTTTTCGTAGAGCCGGCGGCCGTCCCACTA
TCAGACAGCGATTCTTTTAGCGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043501.1\|WP_011201670.1\|3569620_3569848_+\|putative-motility-protein	unknown	unknown	gnl\|CDD\|379452
NZ_CP043501.1\|WP_020451770.1\|3565674_3566484_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226112
NZ_CP043501.1\|WP_020451773.1\|3570291_3570648_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_CP043501.1\|WP_020451768.1\|3562927_3563893_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132883
NZ_CP043501.1\|WP_020451772.1\|3568685_3569207_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_023855707.1\|3550828_3551764_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP043501.1\|WP_020451766.1\|3561162_3562143_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_020451765.1\|3560476_3561010_-\|DUF420-domain-containing-protein	unknown	unknown	gnl\|CDD\|225204
NZ_CP043501.1\|WP_020451767.1\|3562373_3562883_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP043501.1\|WP_003182557.1\|3552491_3552824_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP043501.1\|WP_025811320.1\|3557515_3558163_-\|peptidase	unknown	unknown	gnl\|CDD\|370127
NZ_CP043501.1\|WP_033155124.1\|3551941_3552451_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_096748109.1\|3553874_3554279_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340167
NZ_CP043501.1\|WP_023855705.1\|3552909_3553734_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293813
NZ_CP043501.1\|WP_079289250.1\|3555658_3556357_+\|lysozyme-family-protein	unknown	unknown	gnl\|CDD\|381612
NZ_CP043501.1\|WP_023855703.1\|3554278_3555616_+\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NZ_CP043501.1\|WP_020451769.1\|3563924_3565514_-\|solute:sodium-symporter-family-transporter	unknown	unknown	gnl\|CDD\|236699
NZ_CP043501.1\|WP_023855708.1\|3550490_3550775_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|378913
NZ_CP043501.1\|WP_025811321.1\|3556490_3557477_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|367154
NZ_CP043501.1\|WP_020451771.1\|3566720_3568502_-\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|223588

Protein	Function_ID	Function_description	E-value
NZ_CP043501.1\|WP_011201670.1\|3569620_3569848_+\|putative-motility-protein	gnl\|CDD\|379452	pfam14070, YjfB_motility, Putative motility protein. This family of proteins is regulated in B. subtilis by SigD, and is likely to be involved in motility or flagellin production, Proteins in this family are approximately 60 amino acids in length, and contain two highly conserved asparagine residues.	4.76798e-09
NZ_CP043501.1\|WP_020451770.1\|3565674_3566484_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226112	COG3584, COG3584, Uncharacterized protein conserved in bacteria [Function unknown].	6.1468e-46
NZ_CP043501.1\|WP_020451773.1\|3570291_3570648_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	1.83136e-30
NZ_CP043501.1\|WP_020451768.1\|3562927_3563893_+\|LD-carboxypeptidase	gnl\|CDD\|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	1.49157e-107
NZ_CP043501.1\|WP_023855707.1\|3550828_3551764_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.09736e-74
NZ_CP043501.1\|WP_020451771.1\|3566720_3568502_-\|DNA-helicase-RecQ	gnl\|CDD\|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	0
NZ_CP043501.1\|WP_020451765.1\|3560476_3561010_-\|DUF420-domain-containing-protein	gnl\|CDD\|225204	COG2322, COG2322, Predicted membrane protein [Function unknown].	3.45867e-63
NZ_CP043501.1\|WP_020451767.1\|3562373_3562883_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.0032594
NZ_CP043501.1\|WP_003182557.1\|3552491_3552824_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	3.85328e-19
NZ_CP043501.1\|WP_025811320.1\|3557515_3558163_-\|peptidase	gnl\|CDD\|370127	pfam08795, DUF1796, Putative papain-like cysteine peptidase (DUF1796).	1.70321e-34
NZ_CP043501.1\|WP_096748109.1\|3553874_3554279_-\|hypothetical-protein	gnl\|CDD\|340167	pfam17452, YnfE, Uncharacterized protein YnfE. This is a family of unknown function found in Bacillus.	5.17139e-32
NZ_CP043501.1\|WP_023855705.1\|3552909_3553734_-\|hypothetical-protein	gnl\|CDD\|293813	cd07727, YmaE-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YmaE and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YmaE and Nostoc all1228 proteins.Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. .	2.65923e-68
NZ_CP043501.1\|WP_079289250.1\|3555658_3556357_+\|lysozyme-family-protein	gnl\|CDD\|381612	cd16891, CwlT-like, CwlT-like N-terminal lysozyme domain and similar domains. CwlT is a bifunctional cell wall hydrolase containing an N-terminal lysozyme domain and a C-terminal NlpC/P60 endopeptidase domain (gamma-d-D-glutamyl-L-diamino acid endopeptidase), and has been implicated in the spread of transposons. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).	5.7057e-77
NZ_CP043501.1\|WP_023855703.1\|3554278_3555616_+\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.89024e-37
NZ_CP043501.1\|WP_020451769.1\|3563924_3565514_-\|solute:sodium-symporter-family-transporter	gnl\|CDD\|236699	PRK10484, PRK10484, putative transporter; Provisional.	0
NZ_CP043501.1\|WP_023855708.1\|3550490_3550775_-\|transcriptional-regulator	gnl\|CDD\|378913	pfam12674, Zn_ribbon_2, Putative zinc ribbon domain. This domain appears to be a zinc binding DNA-binding domain.	1.04767e-32
NZ_CP043501.1\|WP_025811321.1\|3556490_3557477_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|367154	pfam02719, Polysacc_synt_2, Polysaccharide biosynthesis protein. This is a family of diverse bacterial polysaccharide biosynthesis proteins including the CapD protein, WalL protein, mannosyl-transferase, and several putative epimerases (e.g. WbiI).	6.9983e-117

>NZ_CP043501.1|WP_025811320.1|3557515_3558163_-|peptidase
MNLKEIKGQYNAVFSLGHLCLTAIQLKNNDLRPFSGPLDWVTIHSLTDLNLLLRNRFTGFMEPKNLRVIGYNTGKKKEEGSTIYVSDDFYNIGSVHDFDANQNTLDHLATYPEVIEKYNRRIDRFIEKMSTSKRILFVRTEGEGSFKEAQELELVLSDLVQHDFSVLLVKHSKVNGIVEKNWPLEKTCTVELPDKEIWESNNDLWASLFKGITLV
>NZ_CP043501.1|WP_025811321.1|3556490_3557477_-|polysaccharide-biosynthesis-protein
MFENKTIFITGGTGSWGQELILQLLSLNPKKLIVFSRNEERQVQMRRQIEDPRLTFFIGDIRDRKALNTGLKGVDYVFHLAALKHVPVCEEQPLEALKTNVTGTENVIEAAIENGVKKVINVSTDKAADPANFYGMTKAIGEKLIVYANHLYSDTDFICVRGGNVLGSSGSVLQLFKDQIREKNQVSITDKRMTRFFLTKEKTIRLLLKAAESGQGGEIFIMNSPACRILDMAEVLIEAYGNEKTSIAETGARPGEKLHELLISPHERQHAVSFTNDLAVVLPAIKMPELHKKYADCQPLETDHLSSKDFLISKKEVREMLKEGGFLE
>NZ_CP043501.1|WP_079289250.1|3555658_3556357_+|lysozyme-family-protein
MRLYTVLHQGATEVKPLKKKKSGCLAGAGCLSFFVFVPLIIFFAISGLEQLKWLPLDTESNILERLKDYKPLVEEELDEQDLSQYTALLLGMMYQESKGRGGDPMQSSESLGMKRNEIDDPKASIKQGVRHFTAMYKKGQKKGVDIETIIQSYNMGSGYIDYVSKHGGKHSEKLAKAFSEEQVKKNPDLYNCGGDTNNFRYPYCYGDYSYTEKVMERTKKVEEHIEGLTLEH
>NZ_CP043501.1|WP_023855703.1|3554278_3555616_+|APC-family-permease
MKNETALKRSLTLGPLVVIGLAYMDPLVVFDSYGVVAQLTKGHVPAAYIFTVAALLLTALSYGSMVKAYPKAGSVYTYAYESIHPHAGFLAGWTIMLDYLFLPMVNFAIGSAYLTAAFPEVPHGFWVVLLALSITVVNILGIRLTANITGLFVAFQVIVALTFAGFMIAGLADGLGTGELVSADPFFRSDIEPSLIVSGATILCFSFLGFDAISTMSEETVNPKKNIPLAIFLTVAIGGTLFTAISYLMQQIYPSYDSFQHADSASLEIALYTGGAFLKSFFLAGTMVAVVSSSLSSHASASRLLYAMGRDSSLPKRFFGYVHPTLKTPVFNIMFIGLISLTAMIGELEVIYSFISFGALIGFIFVHLSVIGHYYIRKQERGFLKTLRYLVLPFLGASFCGWLLLSISKNALMIGAGWLIAGFIYFLFRIRTLPNVTFGFDRDPR
>NZ_CP043501.1|WP_096748109.1|3553874_3554279_-|hypothetical-protein
MTSKSPYVKNTEIKTYFICFFALEQLYKTSFFRIKIATVANPLKKGKEYEGMDILRGYVEAVKRNMETMNASDYDGKEEDLRRQQEELERYEQRLKEKSASADRFDQVVDAAVDSAAGDISFSQLEHMYQQEGS
>NZ_CP043501.1|WP_023855705.1|3552909_3553734_-|hypothetical-protein
MTNYICTTCGVQYDAAPKEPAECIICNEERQYVNHSGQAWTTLEEMKQSGRFQNEIALEEERLYSLTTTPEFGIGQSAYLIQEPGFNLLWDCITYLDQRTIENIERMGGVQAIALSHPHYYAAQTEWAEMFDAPIYIHEDDKQWVQRPSSRIVFWSGDSLKLSSGLTLHRLGGHFKGGAVCHWANGNGGKGILLSGDIIQVVQDRRWVSFMYSYPNLIPLPAGKVEQIADQLKNVPFNRLYGAFRRSVKNHAGERVQLSAARYAEALLGTLFST
>NZ_CP043501.1|WP_003182557.1|3552491_3552824_-|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEHNQETTEKQVRAELDEETLFLVSQTFKALSDPTRIKILHLLSQGEHSVNEIAEKLSLLQSTVSHQLRFLKNLRLVKSRRAGTSIFYSPEDQHVLDVLQQMIDHTQHD
>NZ_CP043501.1|WP_033155124.1|3551941_3552451_+|hypothetical-protein
MYYFLQFFAIVSFVYIKFKRSVGYQPLKPARMLFRIILFSGIFVFLLTMSALHPLSYFYDLIGIALGLILTAYALKHVSIENRDGILYFRTHLWIELIVLLLFLYRFLYRIAEIGQLQTAVSNGGSAAYGALFAQDPATMIGFFVLAVYYVGFSFFVLKKGRNEEKRSA
>NZ_CP043501.1|WP_023855707.1|3550828_3551764_-|YafY-family-transcriptional-regulator
MKIDRLLAIVILLINKRQVQAKELAGMFEVSVRTIYRDIEAINQAGIPIVTSQGAGGGISIMERFRLENKLLSADELAAITTALESVSSTYEVLHHGSALEKIRFLVSEEEMPEFRKKTEKWFVDISSWGESPVIKEKIRLLDEAADSTRAVSFTYVNREGQTGTRKAEPHTLVLKGRHWYLYAFCLKRQAFRFFKLLRMKDVQMLEEKFERKEVDLSSLPWETSWYKPDNMIELTLLIKPSGESLAREWFGSEALTYENGQCVATVSYPEDQWLYGFLLQFGTHIEVLTPPRIRQKIKNLANQIVHLYET
>NZ_CP043501.1|WP_023855708.1|3550490_3550775_-|transcriptional-regulator
MEHHVCQSCGMPMTSELFGTEKDGGKNRDYCMYCYENGAYTHPDATLKEMIDICVPYIKEEGKTEAEARSLLERTLPHLKRWASDTQTKGGQRR
>NZ_CP043501.1|WP_020451765.1|3560476_3561010_-|DUF420-domain-containing-protein
MTHTQKNKNYTGIVVALTIIINGVIALLFFMPKSDKFAHLDLTFLPLLNAVCNSFTFIFLVAALIMIKQKNIKAHKRFIFAAFTTTFIFLVSYLTYHSLMPDTHFGGEGIIRPIYYFILITHIVLSALIVPLALFTLFRGLSMQVERHRKIARWTMPLWLYVSLTGVLVYMMISPYY
>NZ_CP043501.1|WP_020451766.1|3561162_3562143_-|hypothetical-protein
MKKRIFSLLMLMSAFVLVLAACQQADPKGSYATAYKKLISAKSYEFSSDIGLKVDASNLGAEDKQVADMLNDATLTISGKTNAETKQSEAVIKAKLKVQNMSLDFDIPVYMDEKKQVGYIKIDSVLDSFGFFLGTAGMNFDSVKGKYLEFPLEDDKTSSQDTDELQKQLMESIKEAADNLPADKFEKADLTDKEKEQGAAQKVAFSFSDKEIKAAVVKFIEIAGKASGEAVPKSELNKIKDGLKDVTFKKFDVTSTIDDKENLLTENADISLSVDSKKAPQSLGITASTTYKNIDGDVKFEHKPNKEDIVTEEEFEKLMAKDAMNF
>NZ_CP043501.1|WP_020451767.1|3562373_3562883_+|GNAT-family-N-acetyltransferase
MITDEEMQKDSSGLQKELNELQFQLFRMRENMKDISKDSRVLGIDQSKDDEWMIVHSIDDGRTCKIMLSDCQSPYRGRCDFSLVASYKEEKCAIHIGDIKGPAGYGYGSICMKYLKEKAREHNIPVITGDIAERDWDHVDRLIHFYEKHHFEVTIDPGLKSGEIQWQDL
>NZ_CP043501.1|WP_020451768.1|3562927_3563893_+|LD-carboxypeptidase
MFPEKLQPGDEIRVIAPSRSLSLLNTDKIEKARTVLNNLGFRISFSAHANEIDECSSSSIQSRVSDLHDAFSDQRVKGILTVLGGYNSNQLLSHLNYELIKANPKVFCGFSDITALSAAIYAKTGLVTYSGPHFSSFSMGYGLNYMTDYFLKCCCASGVYDVEPSSMWCEEIETEECPKQNSGPVVINEGSADGKIIGGNLCTLNLLQGTEYFPDIKNAVLFLEDDWESPAAFFDRDLQSLLHLPDFSGVKAVLIGRFQTASAVTLERLKQIVQTKKELSQIPVIANIDFGHTTPFFTFPIGGRCRIDAQKEHVSLCITKH
>NZ_CP043501.1|WP_020451769.1|3563924_3565514_-|solute:sodium-symporter-family-transporter
MLWIIMTFLLINAGIFIFSYLRTKDINLKTSDGYFLGGRSLTALYIGSSLLLTNLSTEQMVGLNGQSYSGTMSAMAWEVTAPLALIMLAFVFLPRYLSSGVTTIPDFLEKRYDQRTRQIVSILLLLGYATSFLPTVLYSGALVLDQVFNISSALGISTFATVFFISLVIGAASCCYIFFGGLKAAASADAIYGAGLILGGLFIFVLGIMAIGDGSLLNGYTELTSVHKEKLNAITADNAAEVPWPTIFTGLLVNNLFYWAVNQSIVQRALGAKNLAEGQKGALLAGVFKTIGVFYLVLPGVIAYHLYGGHIENADTVYPKLIVDLLPTALIGVFAAILFGAILSSFNGSLNSTITLFTLDLYKPIFKPEAKEEELVKTGRIFVVILAAVSIIIAPFILFAPSGLYNYLQEMFGFFNVPVLAAVVVGFFTKKVPALAVKWAIFAHIVLYTISKIYFGHIHFLYILAVLFPFSVLLMLFIGKLKPRPSEFKLEKNAKVDLRPWKHAKLASILVICLMACIYLLFSPWGLAK
>NZ_CP043501.1|WP_020451770.1|3565674_3566484_-|LysM-peptidoglycan-binding-domain-containing-protein
MKKTFMSFVAVAALSSTAFGASASAKEVTVQKGDTLWGISQKQGVNLQDLKEWNQLSSDLIIPGQKLNVSEKQTEEKKQYTIKKGDTLWKIAQQFGVSVNDLKNWNNIKSDIIYPNTSITVDGQATVQAAAAQPAETKPAVQKEAKVEKAAPAPKQEKETASRSNKSQSSQSAAKELTVTATAYTANDGGMTGVTATGFDLNANKNAKIIAVDPNVIPLGSKVYVEGYGEATAADTGGAIKGNKIDVFVPSKSAAKNWGVKTVKVKVLK
>NZ_CP043501.1|WP_020451771.1|3566720_3568502_-|DNA-helicase-RecQ
MLEKAEALLQHYYGYPSLRPGQKKAIQSVVSEKRDTACIMPTGGGKSICYQIPALLMEGTTIVISPLISLMKDQVDALNQLGIQAAYVNSSLGHGEIAERLSVLKEGGYKLFYVTPERLTSPDFIRVLSRIHIPLTAIDEAHCISQWGHDFRPSYRHIESFLNSLGTRPVVLALTATATPEVHEDICTQLGIEKESTVFTGFSRDNLTFKILKGENKDRFIESYVEKNRSEAGIIYTATRKEAERISSRLSQKGIAAGCYHGGMNDEERDRQQDLFLNDEISVMTATSAFGMGIDKSNIRYVIHAQIPKNMESYYQEAGRAGRDGLDSECILLFSPQDIRLQRFLIEQSTEDEDIRAQDVKKLRQMVDFCHTEGCLERFILSYFGEVSTEDCGRCSSCLDTRSITDVTKEAQMVLSCIIRMGERFGKTMVAQVLAGSKNKKVTENGFQQLSTYGILKNRSIADISDFIEFLIADEYIQMSDGTYPVLFVANKGRNVLLGREAVMRKEKMQTSQIVKDDELFERLRALRRKLAQEQGVPPFVIFSDETLREMSGKVPLTDEELLSVKGVGEQKRVKYGAVFLQELQAYKTEKEA
>NZ_CP043501.1|WP_020451772.1|3568685_3569207_-|hypothetical-protein
MDWLEFVSATVQSLAWPATLMMCVLLLKEPLSERMKELIKLKYKDFELEFDKRLQKLVSVREKRLSGLTSVRSAPAGENMIESAWSDVHNVLRETASTFDQNAIRLEGDELIQMLHDRGMIQDDAASVLSELSALRRDASDRASITGALAYKTLCLEEAKRLQLLAEQQTAIK
>NZ_CP043501.1|WP_011201670.1|3569620_3569848_+|putative-motility-protein
MSKVLTSLTDTHVKEVVMLDIAVLSMAMSQAALYQNVQMSLTKTALDTAEQSAQQLVDMVQAPHPVSGHHIDLKG
>NZ_CP043501.1|WP_020451773.1|3570291_3570648_-|MmcQ/YjbR-family-DNA-binding-protein
MLTREDIFKHVKEKFGTLPDYPFQKFPYYAALRHESNEKWYGLVMNVLLEKLGLDGNDEIDILNLKCPPEISGSLRNGKSILPGYHMDKENWISLVLERIDSEEEVYNLIEQSFNLTK

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Crispr_ID: NZ_CP043501_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043501_2

3702213-3702428

Unclear

Consensus_repeat	Method
AAGCCTTGCAAGAAGGACTACGATTATTGCAAAAAGGATTATTACTACCATGAG	CRISPRCasFinder

1 spacers

DinG,cas3

The CRISPR arrays of NZ_CP043501_2

>merge|NZ_CP043501|2|3702213-3702428|CRISPRCasFinder
GATCCTTATAAGAAGGATCACGATTATTGCAAAAAGGACTACTACTACCATGAGCCTTGCAAAAAAGACTTCTATTACCATGAACCTTGCAAGAAGGATTACGACTATTGCAAAAAGGATTATTACTACCATGAGGATTACAAAAAAGACTACGATTACCACAAGCCTTGCAAGAAGGACTACGATTATTGCAAAAAGGATTATTACTACCATGAG

>NZ_CP043501|2|2|3702213-3702428|CRISPRCasFinder
GATCCTTATAAGAAGGATCACGATTATTGCAAAAAGGACTACTACTACCATGAG	CCTTGCAAAAAAGACTTCTATTACCATGAACCTTGCAAGAAGGATTACGACTATTGCAAAAAGGATTATTACTACCATGAGGATTACAAAAAAGACTACGATTACCAC
AAGCCTTGCAAGAAGGACTACGATTATTGCAAAAAGGATTATTACTACCATGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043501.1\|WP_003182873.1\|3704440_3704737_-\|cell-division-regulator-GpsB	unknown	unknown	gnl\|CDD\|237616
NZ_CP043501.1\|WP_020451911.1\|3705485_3705755_-\|spore-coat-protein-CotD	unknown	unknown	gnl\|CDD\|371387
NZ_CP043501.1\|WP_020451914.1\|3709691_3710198_-\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376324
NZ_CP043501.1\|WP_023857414.1\|3710370_3710790_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223149
NZ_CP043501.1\|WP_020451899.1\|3692730_3693234_-\|methyltransferase-YpbQ	unknown	unknown	gnl\|CDD\|224669
NZ_CP043501.1\|WP_075213139.1\|3695004_3696321_-\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP043501.1\|WP_075213140.1\|3697259_3698762_-\|carboxypeptidase-M32	unknown	unknown	gnl\|CDD\|341054
NZ_CP043501.1\|WP_075213138.1\|3694380_3694932_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP043501.1\|WP_020451916.1\|3710808_3711255_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372950
NZ_CP043501.1\|WP_020451906.1\|3700905_3701082_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_039072834.1\|3705996_3707310_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225895
NZ_CP043501.1\|WP_075213141.1\|3698877_3700797_-\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP043501.1\|WP_003182857.1\|3692571_3692667_-\|Fur-regulated-basic-protein-FbpC	unknown	unknown	gnl\|CDD\|380216
NZ_CP043501.1\|WP_039072801.1\|3704817_3705369_-\|DUF1273-domain-containing-protein	unknown	unknown	gnl\|CDD\|237461
NZ_CP043501.1\|WP_075213142.1\|3701278_3701641_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_165389271.1\|3707315_3709586_-\|DEAD/DEAH-box-helicase	cas3	mkCas0139_cas3_CAS-I	gnl\|CDD\|224126
NZ_CP043501.1\|WP_075213143.1\|3702754_3703906_-\|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223194
NZ_CP043501.1\|WP_026579400.1\|3711658_3712030_-\|YppE-family-protein	unknown	unknown	gnl\|CDD\|378052
NZ_CP043501.1\|WP_020451903.1\|3696317_3696902_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP043501.1\|WP_020451900.1\|3693241_3694339_-\|chalcone-synthase-BcsA	unknown	unknown	gnl\|CDD\|225958

Protein	Function_ID	Function_description	E-value
NZ_CP043501.1\|WP_075213138.1\|3694380_3694932_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	4.61497e-14
NZ_CP043501.1\|WP_003182873.1\|3704440_3704737_-\|cell-division-regulator-GpsB	gnl\|CDD\|237616	PRK14127, PRK14127, cell division regulator GpsB.	2.30627e-48
NZ_CP043501.1\|WP_020451911.1\|3705485_3705755_-\|spore-coat-protein-CotD	gnl\|CDD\|371387	pfam11122, Spore-coat_CotD, Inner spore coat protein D. This family is conserved in the Enterobacteriaceae family. CotD is an inner spore coat protein that is expressed in the middle phase of mother cell gene expression. Along with CotD, CotH, CotS and CotT it is assumed to assemble into the loose skeleton of the matrix, between the shells of SpoIVA and CotE. Coat proteins do not share much sequence similarity between species, but this does not imply they do not share secondary, tertiary, or quaternary features.	6.15083e-12
NZ_CP043501.1\|WP_020451914.1\|3709691_3710198_-\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|376324	pfam00358, PTS_EIIA_1, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1.	1.45255e-68
NZ_CP043501.1\|WP_023857414.1\|3710370_3710790_+\|hypothetical-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	4.96863e-07
NZ_CP043501.1\|WP_075213143.1\|3702754_3703906_-\|class-I-SAM-dependent-RNA-methyltransferase	gnl\|CDD\|223194	COG0116, COG0116, Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair].	0
NZ_CP043501.1\|WP_075213139.1\|3695004_3696321_-\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	0
NZ_CP043501.1\|WP_075213140.1\|3697259_3698762_-\|carboxypeptidase-M32	gnl\|CDD\|341054	cd06460, M32_Taq, Peptidase family M32, which includes thermostable carboxypeptidases TaqCP, PfuCP and FisCP. Peptidase family M32 is a subclass of metallocarboxypeptidases, distributed mainly in bacteria and archaea, whose members contain a HEXXH motif that participates in coordinating a divalent cation such as Zn2+ or Co2+. It includes the thermostable carboxypeptidases (E.C. 3.4.17.19) from Thermus aquaticus (TaqCP) and Pyrococcus furiosus (PfuCP), which have broad specificities toward a wide range of C-terminal substrates that include basic, aromatic, neutral and polar amino acids. These enzymes have a similar fold to the M3 peptidases such as neurolysin and the M2 angiotensin converting enzyme (ACE). The keratin-degrading extremophilic eubacterium Fervidobacterium islandicum M32 carboxypeptidase (FisCP) plays an important role in cellular metabolism, and significantly enhances the degradation of native chicken feathers. It has been shown to mainly cleave the C-termini of peptides with a basic amino acid sequence. Novel M32 peptidases from some eukaryotes: protozoa Trypanosoma cruzi, a causative agent of Chagas' disease, and Leishmania major, a parasite that causes leishmaniasis, have been identified, thus making these enzymes an attractive potential target for drug development against these organisms.	0
NZ_CP043501.1\|WP_020451899.1\|3692730_3693234_-\|methyltransferase-YpbQ	gnl\|CDD\|224669	COG1755, COG1755, Uncharacterized protein conserved in bacteria [Function unknown].	1.36683e-49
NZ_CP043501.1\|WP_020451916.1\|3710808_3711255_-\|hypothetical-protein	gnl\|CDD\|372950	pfam14179, YppG, YppG-like protein. The YppG-like protein family includes the B. subtilis YppG protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 115 and 181 amino acids in length. There are two completely conserved residues (F and G) that may be functionally important.	4.72983e-17
NZ_CP043501.1\|WP_039072834.1\|3705996_3707310_-\|hypothetical-protein	gnl\|CDD\|225895	COG3359, COG3359, Predicted exonuclease [DNA replication, recombination, and repair].	2.23779e-97
NZ_CP043501.1\|WP_075213141.1\|3698877_3700797_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	2.69806e-127
NZ_CP043501.1\|WP_003182857.1\|3692571_3692667_-\|Fur-regulated-basic-protein-FbpC	gnl\|CDD\|380216	NF033217, Fur_reg_FbpC, Fur-regulated basic protein FbpC. Members of this family are FbpC, Fur-regulated basic protein C. This protein has also been described as MrgC (metal-regulated gene C). Members of this family are found so far only in the genus Bacillus, although the small size may have interferred in gene-finding.	8.14213e-08
NZ_CP043501.1\|WP_039072801.1\|3704817_3705369_-\|DUF1273-domain-containing-protein	gnl\|CDD\|237461	PRK13660, PRK13660, hypothetical protein; Provisional.	2.56976e-100
NZ_CP043501.1\|WP_165389271.1\|3707315_3709586_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|224126	COG1205, COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only].	0
NZ_CP043501.1\|WP_020451900.1\|3693241_3694339_-\|chalcone-synthase-BcsA	gnl\|CDD\|225958	COG3424, BcsA, Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism].	1.62894e-154
NZ_CP043501.1\|WP_026579400.1\|3711658_3712030_-\|YppE-family-protein	gnl\|CDD\|378052	pfam08807, DUF1798, Bacterial domain of unknown function (DUF1798). This domain is found in many hypothetical proteins. The structure of one of the proteins in this family has been solved and it adopts an all alpha helical fold.	4.36685e-38
NZ_CP043501.1\|WP_020451903.1\|3696317_3696902_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	7.0043e-121

>NZ_CP043501.1|WP_075213142.1|3701278_3701641_-|hypothetical-protein
MNSVSQEIQDLSIQSLESTFNKLTNAYKSTKEKGSNTTLVKKRLNALKIGLESLKGIWNGEDFGYNEEIILTSKEVLQGIIPSIEKQIAKAKEGSPQKTLNERRLTALKLAIESLENRLI
>NZ_CP043501.1|WP_020451906.1|3700905_3701082_-|hypothetical-protein
MLNSDHIHMIQKALETSENQLEDIGEERLTYAKEELKNAISHMESTDHPFLTHSIYRK
>NZ_CP043501.1|WP_075213141.1|3698877_3700797_-|ATP-dependent-DNA-helicase
MTASRLPFSLTKTKNFYEELNNWIGDVFYDILPEKGFDLRDEQIFMAFQLERAFKEKKVMFAEAGVGTGKTLVYLLFALSYARYTGKPAVIACADETLIEQLVKKEGDIYKISEHLGLTIDARLSKSHDQYLCLKKLEKTMQRSDDEKWLDLYESLPSFVHESQGMQSFYPYGDRKEYSSLSNDEWSEIGYDSFQDCLTCDMRHRCGLTLSRDHYRKSTDFIICSHDFYMEHVWTEEARKREGQLPLLPEHSAVVFDEGHLLEFAAQKALTYRVKQSTLEMFLERLLGNDIREEFAELVEEALRANDEFFGLLSENAEKAEGSERMRIKDHANLKKAAAELYDLLEKIGEALVFEGELYTIDQYALTVVEEYLEQMAYSLSLYRKNAISWLEQKELESTFVVMPRTVSEVLGEKVFSKQIPFIFSSATLSENGSFDYLATSLGIRDYLSFTVDSPYDYEEQMKVYIHRIEEKEAKEKAAIRAIKESGGKTLILFPSFEELLSFKRRTAQESFSFPVYFEGDEEISTIVEKFQTVEESVLCSVHLWEGLDIPGDPLQHVIIWSLPFPPHDPVFEAKRSGLENAFREVDLPYMLLRLRQGIGRLIRSNSDRGTISIFAGDEQEWNVIKEVESVLPVQPVYV
>NZ_CP043501.1|WP_075213140.1|3697259_3698762_-|carboxypeptidase-M32
MSINTYEKEFLETLKKISRYEQAINVMYWDMRTGAPRKGEESRAEAIGQLSADVFQMRTSPRMKELLDALAEQKQDLPADTQKAVEEAKKEYDLNSKIPEEEFKEYTTLTSKAESVWEKAKKASDFSLFAPYLEKIIDYKKRFISYWGYEGHPYNTLLDQYEPGVTVEKLDGLFSELREAIVPLVQKIAASDQKPDTGFVHERFPKERQRDVCHFFLKELGYDFEAGRLDETVHPFQVTISQGDARVTTAYNENDFRSAVFGTIHECGHAIYEQNIDEALGGTNLADGASMGIHESQSLFYENFIGRHQGFWKRYFEKIKEASPDQFAGVTAEGFYRAVNESKPSLIRIEADELTYPLHIMIRYEIEKAIFSGEVSVGDLPKLWNDKYEAYLGIMPPDDAKGILQDVHWSGGDFGYFPSYALGYMYAAQLKSSMLKDFPEFDRMIENGEFEPIRKWLTEHVHIHGKRKKPLDIIKSATGEELNVRHLIRYLKEKYTTLYL
>NZ_CP043501.1|WP_020451903.1|3696317_3696902_-|xanthine-phosphoribosyltransferase
MEKLKRKIAEHGTVLSDEVLKVDSFLNHQIDPELMLAVGEEFASLFREEGVTKIVTIESSGIAPAVMAGLKLGVPVVFARKRQSLTLTENLLTASVYSFTKKTESTIAVSASHLSKDDKVLIIDDFLANGQAAKGLVSIIEQAGAKVCGIGIVIEKSFQTGREELDNLGIRVESLARIASLADGKVTFLQEVGS
>NZ_CP043501.1|WP_075213139.1|3695004_3696321_-|purine-permease
MKLTAGKTVSLSIQHVLAMYAGAVVVPLIVGGALGLTPAELTYLVSADILMCGVATLLQVWKNRFFGIGLPVVLGCTFTAVSPMIAIASKYGIPAIYGSIIAGGVIVVIVSFFFGKLVKFFPPVVTGSVVTVIGITLIPVAMNNMAGGEGSSDFGELSNLALAFSVLLVIVLLYRFTTGFIKSISILIGLIAGTAGAALIGKVDFTEVANAGWVQMIHPFYFGTPVFEITPILTMSLVLIVSLVESTGVYFALGDLTDRRLTEKDLAKGYRAEGIAVLLGGVFNAFPYTAYSQNVGLVQLTGVKKNSVIALAGAFLILLGLFPKAAALTTIIPKPVLGGAMVAMFGMVIAYGIKMLSRVDFGKQENLLIVACSIGLGLGVTVVPQMFQNLPDAVKLLTENGIVAGSFTAILLNAIFHIHPFSRHAEQPEAVPTEKSAV
>NZ_CP043501.1|WP_075213138.1|3694380_3694932_-|GNAT-family-N-acetyltransferase
METVNELVERISTKDGGEAVIRPVKMADAPDIIEAVKDVIQTGVYIQKERPRTLEEERAFISDMMEKDNMYAAVEIDGAVYGIARVIRGDLKMKRHTGLFRTWLHSKAQGLGIGREIMSYTLNWCRLHRLHKLCLTVFSANKAALSLYEKSGFIIEGVQKEQVFADGKYENEVLMAYFFERST
>NZ_CP043501.1|WP_020451900.1|3693241_3694339_-|chalcone-synthase-BcsA
MAYVISAGTSLPRCHVDQKEAAVFAREMFKDSFKDIDRLLSAFQNGEIASRQFVMPLDWYKESRSFKEKNQAYIEMAVRHSAEAVSNCLSDERFLKKEIPFEKIEAIFFISSTGISTPGIEAKLMNILPFSKQTKRIPIWGLGCAGGASGIARAFEYCKAFPKAHVLVIAAELCSLTFQKDDQSKSNLIGTSLFGDGIAALLMCGKEADISSARLEVLPEVVSSQSATLEDSEDVMGWEINDNGFRVVFSRDIPTLIKTHLKNDVEAFLNREQLALENIQVFLAHPGGKKVLDAYIASLGFSEAHIDCSRKILARHGNMSSATVMHVLKEYCLHGSPIPGKYGLLGALGPGFSSELLLLKWTKRE
>NZ_CP043501.1|WP_020451899.1|3692730_3693234_-|methyltransferase-YpbQ
MFWTILSIFAAQRLLELAVAKFNEKNALKEGAVEYGRRHYPYIVAMHVLFFICLIWETIAFQRGPLPMALVVLTGLIFTQALRYWALFSLGRCWNTKILVIPGTNLVRKGPYQWFKHPNYVAVALEFLLLPLLFQAYATALLFTVLNAAVMYIRIRTEEQALEKLHH
>NZ_CP043501.1|WP_003182857.1|3692571_3692667_-|Fur-regulated-basic-protein-FbpC
MTMFFLLAAVSTYSLLIGYVLKGIAGANPQK
>NZ_CP043501.1|WP_075213143.1|3702754_3703906_-|class-I-SAM-dependent-RNA-methyltransferase
MKTYTLIATAPMGIEAIVAKEVRDLGYDCTVDNGKVVFEGDALAICRANLWLRTADRVKVQVAEFTAKTFDELFEKTKAVDWSAYLPEHASFPVTGKSVKSVLASVPDCQRIVKKAIAEKLKSAYQTQGGWLEETGPEYKIEVSLLKDKAVITLDSSGAGLHKRGYRTGQGEAPLKETLAAALIQLTNWTPDRPFVDPFCGSGTIPIEAALIGQNIAPGFNRDFASERWEWISKEVWDQARLEVEDKANYDQPLSISGYDLDHRMIEIAKANAEEAGLADFIEFKQMQVKDFRAKEEYGVIVGNPPYGERLGEKKAVEAMYKDMGEAFAGLDTWSVYMLTSNERFEECYGKKATKKRKLFNGFIKTDYYQYWGKRPPKPNKEK
>NZ_CP043501.1|WP_003182873.1|3704440_3704737_-|cell-division-regulator-GpsB
MLADKVKLSAKEILEKEFKTGVRGYKQEDVDKFLDMVIKDYEAFHQEIEELQQENLQLKKQLEEANKRQPAQSNTTNFDILKRLSNLEKHVFGSKLYD
>NZ_CP043501.1|WP_039072801.1|3704817_3705369_-|DUF1273-domain-containing-protein
MKVLAVTGYKPFELGIFKQDDKALFYIKKALENRLTALLEEGLEWILISGQLGTELWAAEVAFSLQEEYPDLKVAVITPFLEQEKKWNEKNQEQYEAVLAASDFTESLTHRPYESPVQFKQKNRFFIEKADGLLILYDEEREGSPVYMLNEAKKAQEKRDFPIYTITMDDLRVTVEESSFYEE
>NZ_CP043501.1|WP_020451911.1|3705485_3705755_-|spore-coat-protein-CotD
MHCKPHVMAPIVHPTQCCYNHTQSKTVVPHIHPQHTTNVNHQHFQHVHYFPQTQSAVNQASHQHFVSPGAGMMPGPGAMPGPGMGMGPY
>NZ_CP043501.1|WP_039072834.1|3705996_3707310_-|hypothetical-protein
MSLKRKLNRYKHHLGNQAKEEKTDSPAEKRTSVSVGFEKEWAEFGVKPYVFEDCYCLIREVVYPLTHVHGHYAFSELHETVRRWNNSDVSHSLSSKGYTPSQLFFFDTETTGLGGGAGNAIFLLGHARVYDDRVVVKQHLLPKPGHEAALYHSFLSEVDIQSLVTYNGKAFDWPQVKTRHTLIRDRVPKLPDFGHFDLLHGSRRLWKHKFDRVSLGTVEKEELGVVRTEDTPGYLAPMMYFHFLKEERPEIIEGVLRHNELDVLSLISLYIHLSKKILTPEQTAEANEKYAMAKWLLANRETELATAQLQELEKKPFEQSERASFDLSMQYKKQGMLKEAASLWLKLQNGTDGKTAWRAGIELAKYFEHRKRDIRAALEVTDNLMLQHGSQKFELTEKEVAGLLKRRERLERKFGRNIPRASAENDDLRKPNISSML
>NZ_CP043501.1|WP_165389271.1|3707315_3709586_-|DEAD/DEAH-box-helicase
MFQKRNLTDMIQLLKEDQAFSKQIVHWHTIEEKEADYRDFPEGLDKRIVHALQQRGIEKLYSHQADAFLHSAAGKNVTLVTPTASGKTLCYNLPVIQRITEDQDARSLYLFPTKALSQDQKSELNELIDEIGASINCYTYDGDTSPSIRQKVRKAGHIVITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHVYRGVFGSHVANVIRRLMRIAEFYGSKPQFICTSATIANPLELAETLTGQPMHLISNNGAPSGRKHFLFYNPPMVNRSLNIRKSATLEVRKLASEFLKNGIQTIVFARSRVRVEIILTYLQEVMKPIVGPHSIQGYRGGYLPNERRVIEKGLRSGDIKGVVSTNALELGVDIGQLQTCIMTGYPGTISSAWQQAGRAGRRHNEALIVMVASSAPLDQYIVQNPDYFFKQNPETAVINPDNLVILVDHIKCAAFELPFKRTDTFGGAEIEDILDYLAEERVLHLTGNTYHWMNDAFPAHGISLRSASQENVVIIDQSKREKAKVIGEMDRFSAMTLLHDEAIYLHQGIQYQVEKLDWEEKKAFVREVQVDYYTDANLAVLLRVLEVDKEKKTETAVFGFGDVTVQAKATIFKKIKFETHENIGSGPIHLPEEELHTNAAWVQVNDEERQNWNDIKLEEALLGTANVLGHVAALKVMCDPSDLHVFPQIKAVHNEKPTIFLYDRYPGGVGLSQKVYEQMPEIISEAHRLISRCPCESGCPSCIGVGGSGDQTKNNALRLLKGWKG
>NZ_CP043501.1|WP_020451914.1|3709691_3710198_-|PTS-glucose-transporter-subunit-IIA
MLKKLFGIGQKQNEMKEETVFSPVDGQVLELSKVPDPVFSQKMMGDGMAVEPSAGEIVSPVDGEVIQLFHTKHAIGIRSLSGVELLIHIGLETVAMEGEGFTAHVKEGDKVKVGDPLITCDLELIKEKASSTITPIVIMNGDVLERVTKHEEAKAKKSETKLMELKVK
>NZ_CP043501.1|WP_023857414.1|3710370_3710790_+|hypothetical-protein
MDFKENDNHSLSKKDEIQEAVEQLFYNSPFHDILNSFQKLISDQLQNSTISMNIREENEALHVDIAVPESFQNGDIMIEAKSRYLHVALKEKKESGGSSSFTSLSRTVLLPYPVREETMKTSWNQNILTVSFPEQKKHE
>NZ_CP043501.1|WP_020451916.1|3710808_3711255_-|hypothetical-protein
MEERRTAVYPYSGPGAYVQADQQNHHAYHPVQPYYSQETVPYAHPAQRPQAYQQPIEQNVDPFSVYHQPVQQQMQPPLPPFQAFPYQHPYPSPRPNLHQPSQFQSFLSQFKKKNGQFDFSKMMDTAGQMVSTVNQVGALAKGFMGFFK
>NZ_CP043501.1|WP_026579400.1|3711658_3712030_-|YppE-family-protein
MDTQSLLVQTRELIRLVKEAEERYSKGKEEGTEYDFFEVVKPSVERFEQTVKSWLAESLPYIKANRPKYIYEEQLSSVEENANEIFMQSYFCKIHKKRFKDLTESVLYTLKNVEDDILKEDRD

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Crispr_ID: NZ_CP043501_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043501_3

4369498-4369806

Orphan

Consensus_repeat	Method
TATTCTTCCGGCTTTGCTTCT	CRT

7 spacers

The CRISPR arrays of NZ_CP043501_3

>merge|NZ_CP043501|3|4369498-4369806|CRT
TATTCTTCCGGCTCCGCTTCTTTCCCCTTTTTGAGCTCATATTCTTCCGGCTTTTCTTCCACTTTCCCCCTAATTAGCTCGTGTTCTTCCGGCTTTGCTTCTTTCTCCTCTTTCAGCTCATATTCTTCCGGCTTTGCTTCTACTTTCTCCCTTTTCAGCTCATATTCCTCCGGCTTTGCTTCTACTTTCTCCCTTTTCAGCTCATATTCTTCCGGTTTTGCTTCTACTTTCTCCCTTTTCAGCTCATATTCTTCCGGCTTTGCTTCTACTTTCTCCCTTTTCAGCTCATATTCTTCCGGCTTTGCTTCT

>NZ_CP043501|3|1|4369498-4369806|CRT
TATTCTTCCGGCTCCGCTTCT	TTCCCCTTTTTGAGCTCA
TATTCTTCCGGCTTTTCTTCC	ACTTTCCCCCTAATTAGCTCG
TGTTCTTCCGGCTTTGCTTCT	TTCTCCTCTTTCAGCTCA
TATTCTTCCGGCTTTGCTTCT	ACTTTCTCCCTTTTCAGCTCA
TATTCCTCCGGCTTTGCTTCT	ACTTTCTCCCTTTTCAGCTCA
TATTCTTCCGGTTTTGCTTCT	ACTTTCTCCCTTTTCAGCTCA
TATTCTTCCGGCTTTGCTTCT	ACTTTCTCCCTTTTCAGCTCA
TATTCTTCCGGCTTTGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043501.1\|WP_075752023.1\|4377725_4378313_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NZ_CP043501.1\|WP_096748266.1\|4380850_4382506_-\|ATP-dependent-protease-LonB	unknown	unknown	gnl\|CDD\|131948
NZ_CP043501.1\|WP_023855433.1\|4378309_4380634_-\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NZ_CP043501.1\|WP_020452450.1\|4357591_4358500_-\|rod-shape-determining-protein-MreC	unknown	unknown	gnl\|CDD\|237560
NZ_CP043501.1\|WP_020452451.1\|4359628_4360303_-\|JAB-domain-containing-protein	unknown	unknown	gnl\|CDD\|178801
NZ_CP043501.1\|WP_003184042.1\|4358530_4359541_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237562
NZ_CP043501.1\|WP_020452464.1\|4374806_4375637_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|307628
NZ_CP043501.1\|WP_026579130.1\|4373044_4373836_-\|uroporphyrinogen-III-synthase	unknown	unknown	gnl\|CDD\|119440
NZ_CP043501.1\|WP_020452465.1\|4375642_4377004_-\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP043501.1\|WP_023855425.1\|4362320_4363070_-\|prepilin-peptidase	unknown	unknown	gnl\|CDD\|224900
NZ_CP043501.1\|WP_020452466.1\|4377192_4377678_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_020452461.1\|4372066_4373041_-\|porphobilinogen-synthase	unknown	unknown	gnl\|CDD\|236450
NZ_CP043501.1\|WP_020452457.1\|4367705_4367897_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043501.1\|WP_096748264.1\|4367915_4368938_-\|spore-coat-protein-YsxE	unknown	unknown	gnl\|CDD\|274345
NZ_CP043501.1\|WP_020452456.1\|4364603_4367246_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP043501.1\|WP_096748262.1\|4361080_4362115_-\|SPOR-domain-containing-protein	unknown	unknown	gnl\|CDD\|335993
NZ_CP043501.1\|WP_020452463.1\|4373825_4374767_-\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP043501.1\|WP_096748263.1\|4363222_4364527_-\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl\|CDD\|223362
NZ_CP043501.1\|WP_020452452.1\|4360357_4360930_-\|septum-formation-inhibitor-Maf	unknown	unknown	gnl\|CDD\|178901
NZ_CP043501.1\|WP_023855430.1\|4370745_4372041_-\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607

Protein	Function_ID	Function_description	E-value
NZ_CP043501.1\|WP_096748266.1\|4380850_4382506_-\|ATP-dependent-protease-LonB	gnl\|CDD\|131948	TIGR02902, Lon_protease_2, ATP-dependent protease LonB. Members of this protein are LonB, a paralog of the ATP-dependent protease La (LonA, TIGR00763). LonB proteins are found strictly, and almost universally, in endospore-forming bacteria. This protease was shown, in Bacillus subtilis, to be expressed specifically in the forespore, during sporulation, under control of sigma(F). The lonB gene, despite location immediately upstream of lonA, was shown to be monocistronic. LonB appears able to act on sigma(H) for post-translation control, but lonB mutation did not produce an obvious sporulation defect under the conditions tested. Note that additional paralogs of LonA and LonB occur in the Clostridium lineage and this model selects only one per species as the protein that corresponds to LonB in B. subtilis. [Protein fate, Degradation of proteins, peptides, and glycopeptides, Cellular processes, Sporulation and germination].	0
NZ_CP043501.1\|WP_023855433.1\|4378309_4380634_-\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP043501.1\|WP_020452450.1\|4357591_4358500_-\|rod-shape-determining-protein-MreC	gnl\|CDD\|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	8.62235e-92
NZ_CP043501.1\|WP_020452451.1\|4359628_4360303_-\|JAB-domain-containing-protein	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	8.78992e-133
NZ_CP043501.1\|WP_003184042.1\|4358530_4359541_-\|rod-shape-determining-protein	gnl\|CDD\|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0
NZ_CP043501.1\|WP_020452464.1\|4374806_4375637_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|307628	pfam01578, Cytochrom_C_asm, Cytochrome C assembly protein. This family consists of various proteins involved in cytochrome c assembly from mitochondria and bacteria; CycK from Rhizobium, CcmC from E. coli and Paracoccus denitrificans and orf240 from wheat mitochondria. The members of this family are probably integral membrane proteins with six predicted transmembrane helices. It has been proposed that members of this family comprise a membrane component of an ABC (ATP binding cassette) transporter complex. It is also proposed that this transporter is necessary for transport of some component needed for cytochrome c assembly. One member CycK contains a putative heme-binding motif, orf240 also contains a putative heme-binding motif and is a proposed ABC transporter with c-type heme as its proposed substrate. However it seems unlikely that all members of this family transport heme nor c-type apocytochromes because CcmC in the putative CcmABC transporter transports neither. CcmF forms a working module with CcmH and CcmI, CcmFHI, and itself is unlikely to bind haem directly.	3.62265e-29
NZ_CP043501.1\|WP_026579130.1\|4373044_4373836_-\|uroporphyrinogen-III-synthase	gnl\|CDD\|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	2.95934e-69
NZ_CP043501.1\|WP_020452465.1\|4375642_4377004_-\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NZ_CP043501.1\|WP_023855425.1\|4362320_4363070_-\|prepilin-peptidase	gnl\|CDD\|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	2.22339e-32
NZ_CP043501.1\|WP_075752023.1\|4377725_4378313_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	4.31968e-113
NZ_CP043501.1\|WP_020452461.1\|4372066_4373041_-\|porphobilinogen-synthase	gnl\|CDD\|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP043501.1\|WP_096748264.1\|4367915_4368938_-\|spore-coat-protein-YsxE	gnl\|CDD\|274345	TIGR02904, hypothetical_conserved_protein, spore coat protein YsxE. Members of this family are homologs of the Bacillus subtilis spore coat protein CotS. Members of this family, designated YsxE, are found only in the family Bacillaceae, from among the endospore-forming members of the Firmicutes branch of the Bacteria. As a rule, the ysxE gene is found immediately downstream of spoVID, a gene necessary for spore coat assembly. The protein has been shown to be part of the spore coat. [Cellular processes, Sporulation and germination].	2.09975e-148
NZ_CP043501.1\|WP_020452456.1\|4364603_4367246_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP043501.1\|WP_096748262.1\|4361080_4362115_-\|SPOR-domain-containing-protein	gnl\|CDD\|335993	pfam05036, SPOR, Sporulation related domain. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.	0.000745012
NZ_CP043501.1\|WP_020452463.1\|4373825_4374767_-\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	1.71232e-175
NZ_CP043501.1\|WP_096748263.1\|4363222_4364527_-\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl\|CDD\|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	4.03568e-152
NZ_CP043501.1\|WP_020452452.1\|4360357_4360930_-\|septum-formation-inhibitor-Maf	gnl\|CDD\|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	3.67554e-103
NZ_CP043501.1\|WP_023855430.1\|4370745_4372041_-\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0

>NZ_CP043501.1|WP_096748264.1|4367915_4368938_-|spore-coat-protein-YsxE
MEGIQSVLNEYGLTPEYMESVSPKVWKVYTDHGVFALKKLAASRNARFTEQMILLEEKGYRQFVPVYRNRTGEFLTQAGEDVCYLMPWLTLEREEERDQKHEYMFKEIALLHQRTEKELGVRREEILGHYERTKRKWEQQKQKYEEFISRAENEWYMSPFQLQAAMYFKETISAADFALARLEEWYETMKDKESSRMVLNHGQLSVRHFLYNDTGTGYFTNFEKAGHGPPANDLIVFFTRMFKTNPVMCTECVNWFYTYHNVYPLREEEISLFLSYMAYPGPVYGVLNRYDLEKGPGEKEACTMLLKAYWQMKNAEPLVMSIHETEENRKLQEETESPSS
>NZ_CP043501.1|WP_020452457.1|4367705_4367897_+|hypothetical-protein
MRKKFNTHSFQPWLKQVRLVAVQVVLPITIFQGIRTIIFPTTFDVLLLGILIFLACAFHLDWI
>NZ_CP043501.1|WP_020452456.1|4364603_4367246_-|valine--tRNA-ligase
MDNQELTMPTKYDPSAVEKDRYDYWVNGKFFEAKNDPEKEPYTVVIPPPNVTGKLHLGHAWDSTLQDIVTRMKRMQGYDVLWLPGMDHAGIATQAKVEAKLREEGKTRYDLGREKFLEETWKWKEEYADFIRSQWAKIGLGLDYSRERFTLDEGLSKAVREVFVKLYEKGLIYRGEYIINWDPATKTALSDIEVIYKDVQGAFYHMRYPLKDGSGSIEIATTRPETMLGDTAVAVHPEDERYKHLIGKTVILPITGREIPIVGDDYVDMEFGSGAVKITPAHDPNDFEIGNRHNLERILVMNEDGTMNDKALQYKGMDRFECRKQIVKDLQEEGVLFKIEEHTHSVGHSERSGAVVEPYLSTQWFVQMQPLADAAIELQKSEGKVNFVPDRFEKTYLHWMENIRDWCISRQLWWGHRIPAWYHKETGEIYVGAEAPEDAENWEQDKDVLDTWFSSALWPFSTMGWPDIDEEDFKRYYPTNVLVTGYDIIFFWVSRMIFQGIEFTGERPFKDVLIHGLIRDDQGRKMSKSLGNGVDPMDVIDKYGADSLRYFLATGSSPGQDLRFSFEKVESTWNFANKIWNASRFALMNMDGMTYEELDLSGEKSVADKWILTRLNETIETVTQLADKYEFGEVGRHLYNFIWDDFCDWYIEMAKLPLYGEDEAAKKTTRSILAYVLDQTMRLLHPFMPFLTEEIWQHLPHEGESITVAKWPAAVKEYTDTEAAADMKLLVEVIRAVRNIRSEVNTPLSKQIELYIKTSTPEIAERLEENRSYVERFTNPSLLQIGTDIQAVDKAMTAVVSGAELILPLEGLINIEEEISRLQKELDKLTKEVERVQKKLSNEGFMKKAPAHVIEEERAKEADYTAKREAVEKRIAELKN
>NZ_CP043501.1|WP_096748263.1|4363222_4364527_-|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MRLFKTFDEALSWINGRLKFGVKPGLERMEWLLRKLGHPEKKLNAIHVAGTNGKGSTIAFLRTVLNEAGYTAGTFTSPYIITFNERISVDGAPISDDEWTALFNEVGPLVLELEKTEFGAATEFEIITACAFLYFAKYRRTDFVIFETGLGGRLDSTNVVKPMLTVITSIGHDHMAILGGTLKEIAAEKAGIIKHGVPVITAVHQREAAEVIKRKAMETESAFISLHEDCELSGERSLPDGEQFSLKTPLHRYERIETSLIGTHQRQNASLAILAAEWLTAEKHAAISEEELKRGIHKAGWPGRFEKVLNRPLVYIDGAHNKEGVERLAETITSHFDGRNIHVCFSALKDKPYRDMIRKIESFASSIHFTSFDFPRAESAQKLFEQSTADHKTCDEDIGSVFRYIEEQAEDEKAVVIVTGSLYFISAVRAVLTE
>NZ_CP043501.1|WP_023855425.1|4362320_4363070_-|prepilin-peptidase
MFIFYLFTAGLVLGSFFSSAGRRIPEKISLIAPRSLCRACKRKLGLAELIPVLSYLMQRGRCKGCQTPISIVYPAVELSAAILFAFAGMQVGHQGELVIVLALISLLLIVFVSDVTHMVIPDAVLCFFLIVFAVGRFLVPLEPWHSGLSGAFAGGMLPLLTLLLTKGGIGWGDVKLFAVLGIALGSRLLILAFFLSAAAGTVLGLIALLAGKLKKNEPMPFAPAILIGTLISCFYGNPMIEWYLQMARW
>NZ_CP043501.1|WP_096748262.1|4361080_4362115_-|SPOR-domain-containing-protein
MKKRKSKKNSAKKAPQEDPLKVMINGREETIYGNEKEFSNRNEEKKFTFSNWEEKRKAEREISASKEDGAPETDEFTWTPPDEEETVYKDDPKVVAPYQKKNEAKNNRKAKMSLTFPLKRFAATIIFAVLLGTGLGLFALNLATHKEGVPASGSLGADAENGQAVKAGDSGAEEKKSGQKNSGQAGESFHSFAVQAGKFSSKEGAETLASQIADKGYAAVSIAKDDGFYVIAGITGEKQMTSEIGKILIENDFEAWGGKEFPVALEPGLLEPFKEAAELSAKAILGAEVTSQNIADVKAELDGAKSKGESEEVKKSILEAVNLLEKPTAANGWKSQQLLLSQIK
>NZ_CP043501.1|WP_020452452.1|4360357_4360930_-|septum-formation-inhibitor-Maf
MTRQLILASQSPRRKELLDLLQIPYSIVTSNAEEKLIRNFSPAENVKWLAEQKVRAVAEQYPDAVVLGADTIVLYDGAYLGKPKDAEDAKRMLSMLSGQTHSVLTGVCIKDGERCETFFEETEVFFWPLEEKEISAYIATGEPFDKAGSYGIQGKGALFVKQIKGDYYTVVGLPISKTMRMLKTFDLHSF
>NZ_CP043501.1|WP_020452451.1|4359628_4360303_-|JAB-domain-containing-protein
MKLKDFPDEERPRERLLNTGAESLSNHELLAILLRTGTKKESVLQLSSRLLQTFDGLRLLKEASAEELSSISGIGRAKAVQILAALELGRRIHSLACKDRYVIRFPEDAANFLMGDMRFLSQEHFVCLYLNTKNQVIHKRTIFIGSLNSSIVHPREVFKEALKRSAASFICVHNHPSGDPAPSREDIEVTQRLHESGQLLGIELLDHIIIGDQKFVSLKEKGYL
>NZ_CP043501.1|WP_003184042.1|4358530_4359541_-|rod-shape-determining-protein
MFGIGARDLGIDLGTANTLVFVKGKGIVVREPSVVALQTDTKQIVAVGNDAKNMIGRTPGNVVALRPMKDGVIADYETTATMMKHYISKAVKNKGLFARKPYVMVCVPSGITAVEQRAVIDATRQAGARDAYPIEEPFAAAIGANLPVWEPTGSMVVDIGGGTTEVAIISLGGIVTSQSIRVAGDEMDEAIITYIRKTYNLMIGDRTAEAIKLEIGSAEASENGESMEIRGRDLLTGLPKTIEITEKEITAALRDTVTAIVDAVKNTLEKTPPELAADIMDRGIVLTGGGALLRHLDKVISEETKMPVLIAEDPLDCVAIGTGKALEQIHLFKGKN
>NZ_CP043501.1|WP_020452450.1|4357591_4358500_-|rod-shape-determining-protein-MreC
MPQFFTNKRLMLLLLCIIILVAMIGFSLKNDRNATWPEKFIGDTTGVFQTIFHTPAQFFAGFFENIEDLKNTYSENERLRKKLDGQTQYEAKLQELENENKSLRKELGHLKSIKDYTPILATVIARNPDKYEWWNLITINKGSKHGVEKDMAVTDENGNLIGKIKSTKVNNFTSTVQLLSATDRNNRISTVIAANKGKKTVNGIINGYDSEKKALSMEIIEPDEDREVKKGDLVETSGAGGVFPKGLTIGKVTEVEPDSYGLTKIAYVEPAADMYNLDNVIVVDRTLDTVDVNKMDDEEEGS
>NZ_CP043501.1|WP_023855430.1|4370745_4372041_-|glutamate-1-semialdehyde-2,1-aminomutase
MRSYEKSKAAFEDAQRVMPGGVNSPVRAFKSVNMDPIFMERGKGSKIYDIDGNEYIDYVLSWGPLILGHSNEKVVKEIQKTAEHGTSFGAPTELETELAELVIDRVPSIEIVRMVSSGTEATMSALRLARGYTGRNKIVKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPESIAKNTITVPYNDLESMKLVFQEFGEDIAGVIVEPVAGNMGVVPPVKGFLEGLRELTETHGALLIFDEVMTGFRVGYNCAQGYFGVTPDLTCLGKVIGGGLPVGAYGGKAEIMEKIAPSGPIYQAGTLSGNPLAMTAGLETLKQLTPESYQEFSRKADRLEKGISEAAEKNGIPCTFNRAGSMIGFFFTNEPVINYDTAKQSDLGLFAEYYKGMADEGVFLPPSQFEGLFLSTAHTDDDIEHTIQAAERVFERISRSR
>NZ_CP043501.1|WP_020452461.1|4372066_4373041_-|porphobilinogen-synthase
MEASFQRHRRLRTTAGMRKLVRETELRASDFIYPIFVTEEENVKSEVPSMPGVYQLSLDRLKEEMEEVAGLGIQSVIVFGVPEHKDDVGSGAYHNHGIVQKAIAQIKQDFPELVVIADTCLCEYTDHGHCGLVENGEILNDESLVLLAKTAVSQARAGADIIAPSNMMDGFVAAIRDALDQEGFTNVPIMSYAVKYASAFYGPFRDAAGSSPQFGDRKTYQMDYANRREALREAKSDVEEGADFLIVKPTLSYLDIVREVKNEFNLPVVGYNVSGEYAMVKAAAQNGWIEEKALVLEMLTSMKRAGADLIITYFAKDAAKWISE
>NZ_CP043501.1|WP_026579130.1|4373044_4373836_-|uroporphyrinogen-III-synthase
MKHDLPLQGKKVLVTRNKAQAQSFREKVEALGGEAVLTSLISFRPALPREQAQRFRADLESADWLVFTSVNGAKFFFSYLKNAGFSVPFASKAKVAAVGEKTARYLRDRGLSVDLMPELYVAEHLAEALKRNAGRHDKVAVLKGNLSRDVIKKTLTPLGIQVSEWILYETVRDEKGILELKEAAKHASFDFVTFTSSSTVHTFMSILKEESRTWAEKNGTAFITIGPMTKKALSDYGIPSYMPDVYTIDGMLREICRISRKGE
>NZ_CP043501.1|WP_020452463.1|4373825_4374767_-|hydroxymethylbilane-synthase
MRNIIVGSRRSKLAMTQTKWVIKKLEELNPDFTFEIKEIVTKGDRILDVTLSKVGGKGLFVKEIEQAMLSGEIDMAVHSMKDMPSALPEGLVVGCIPKREDARDVLISKSRQKLADLKQGAVIGTSSLRRSAQLLQMRPDLEIKWIRGNIDTRLKKLETEDYDAIILAAAGLSRMGWKDDVVTEFLDPESCLPAVGQGALAIECRGSDEELLSLFSRLNDRYTQLTVTAERAFLHAMEGGCQVPIAGFATMDEDGVIELTGLVASPDGKTAYRETVKGKDPEAVGRECAAVMSEKGAKALIDRVKQELEDNEA
>NZ_CP043501.1|WP_020452464.1|4374806_4375637_-|cytochrome-c-biogenesis-protein-CcsA
MTDTLLARLNEVTIVLYALTVLFYFIDFLQHNRKAGKAAFWLLSIVWILQTVYLFYFMQYTDQFPVLNNAQGLYFYAWVLVTLSLVLTKLLKVEFLVFFTNLIGFSMAAIHTFTPTAQQSAELSGRLVSELLIIHITMAILSYGAFSLSFVFSVLYLFQYRLLKKKKWGKWLLRIEDLPKLDHMAYVLNLIGVPMLLLSLILGIIWSYVSLETLYWADPKVLGSIVLLFLYGYYLFIRIVKELQGRIAAMWNTASFLVLLINFFLLGSFSQFHWFS
>NZ_CP043501.1|WP_020452465.1|4375642_4377004_-|glutamyl-tRNA-reductase
MHILVVGLDYKSAPVDIREKLTFQPDELGQAMSQLKEEKSILENIIVSTCNRTELYAVVDQLHTGRYYMKMFLANWFGLSKEDISPYLKFYENDGAVEHLFRVSCGLDSMVIGETQILGQVRTSFKLAQEEKTIGTVFNYLFKQAVTVAKRCHAETDIASNAVSVSYAAVELARKIFGDLSDKHVLILGAGKMGELAVQNLHGHGIGQVTVINRTFSKAKELAGRFSGAAKSLNELQCALMEADILISSTGASGYVVTKEMIEHVNKLRKGCPLFMVDIAVPRDLDPALSDVEGVFLYDIDDLEGIVEENLKERQAVAEEVELIIEAEIVAFKQWLNTLGVVPVISALREKALTIQAETMQSIERKLPHLSTREKKLLNKHTKSIINQLLRDPILKVKEFASEADAEEKLALFTQIFDIEEAAFPDGENQDERQPVHAFKRQNQQGLTSIASE
>NZ_CP043501.1|WP_020452466.1|4377192_4377678_+|hypothetical-protein
MKKKSVLLPLLLIAVAVYAFLRSGRISLFDGQEEWSVLAGLIGLALFYQGQKEADSAHSFAGLFMTAIGVYFTFKEDYFSRADDFAVIVLILGAALLVKSFKTKEYQYESLLMIAVALYLYFFRQIAAWLKTANIETAYVEAYWPAAFIAVSLLLLFLKRK
>NZ_CP043501.1|WP_075752023.1|4377725_4378313_-|YihA-family-ribosome-biogenesis-GTP-binding-protein
MKVTKSEIVISAVKPEQYPEGGLPEIALAGRSNVGKSSFINTMINRKNLARTSSKPGKTQTLNFYIINDVLHFVDVPGYGFAKVSKTEREAWGRMIETYLTSREELKAVVQIVDLRHAPSQDDVMMYDFLKHYEIPVIVIATKADKIPKGKWEKHAKVVKETLNIEKEDKLILFSSETKKGKQEAWSAIEQMIAR
>NZ_CP043501.1|WP_023855433.1|4378309_4380634_-|endopeptidase-La
MADETKRNIPLLPLRGLLVYPTMVLHLDVGREKSVQALEQAMMNDHMIFLATQKDISIDEPDEDEIFTFGTYTKIKQMLKLPNGTIRVLVEGLQRARILEYHDLDEYTSVKIERIDEETEKDVEDEALMRTLLDHFDQYIKISKKISAETFAAVTDIEEPGRMADIVASHLPLKLKDKQEVLETIDVKARLNKVIDLIHNEKEVLEIEKKIGQRVKRSMERTQKEYYLREQMKAIQKELGDKEGKTGEVQKLTEKIEQAGMPDNVKETAFKELNRYEKIPSSSAESSVIRNYIEWLISLPWNDATEDRLDLNLASQILDEEHHGLEKVKERVLEYLAVQKLTRSLKGPILCLAGPPGVGKTSLAKSIAKSLGRKFVRISLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAGKNNPVFLLDEIDKMASDFRGDPASAMLEVLDPEQNHTFSDHYIEETFDLSKVLFIATANNLATIPGPLRDRMEIITIAGYTEVEKVEIVKDHLLPKQLKEHGLKKSNLQIREQAVLDVIRYYTREAGVRSLERQIAAICRKAAKLIVSGERKRITVTDKNLEDYLGKRMFRYGQAELDDQIGVVTGLAYTTVGGDTLSIEVSLSPGKGKLILTGKLGDVMRESAQAAFSYVRSKAEELNISPDFHEKHDIHIHVPEGAVPKDGPSAGITMATALVSALTGRPVSRNVGMTGEITLRGRVLPIGGLKEKALGAHRAGLKTVIMPKDNEKDIEDIPNSVREGLTFIPVAHLDEVLKHALVGEEK
>NZ_CP043501.1|WP_096748266.1|4380850_4382506_-|ATP-dependent-protease-LonB
MSWTSIALFVQLFFGIIIGLYFWNLLKNQRTQKVTIDRESKKEMEQLRKMRSIHLSEPLSEKVRPTAFKDIVGQEDGIKALKAALCGPNPQHVIIYGPPGVGKTAAARLVLEEAKKNKRSPFQEHSVFVELDATTARFDERGIADPLIGSVHDPIYQGAGAMGQAGIPQPKQGAVTHAHGGVLFIDEIGELHPIQMNKMLKVLEDRKVFLESAYYSEENTQIPKHIHDIFQNGLPADFRLIGATTRMPDEIPPAIRSRCLEVFFRDLEKQELKTVVKKAADKIEKKVAEEGLDLLTRYARNGREVVNMMQIAAGMALTEERDEVTVEDIEWVIHSSQLTPKYEQKIASKPQVGIVNGLAVHGPNSGSLLEIEVTVNKAADKGSINITGIAEEENIGNQSKSIRRKSMAKGSVENVMTVLRTMGVKASDYDIHVNFPGGIPVDGPSAGIAMAAGIFSAIHKVPIDHTVAMTGEISLNGRVKPIGGVIPKIKAAKHAGAKTVIIPHENVQSILKRIEGVHIIPVKTLQEVLDLALVNPPSEMPDGAQMKRESV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NZ_CP043501_3	3.4\|4369639\|21\|NZ_CP043501\|CRT	4369639-4369659	21	NZ_CP043501.1	4369807-4369827	1.0
NZ_CP043501_3	3.5\|4369681\|21\|NZ_CP043501\|CRT	4369681-4369701	21	NZ_CP043501.1	4369807-4369827	1.0
NZ_CP043501_3	3.6\|4369723\|21\|NZ_CP043501\|CRT	4369723-4369743	21	NZ_CP043501.1	4369807-4369827	1.0
NZ_CP043501_3	3.7\|4369765\|21\|NZ_CP043501\|CRT	4369765-4369785	21	NZ_CP043501.1	4369807-4369827	1.0

1. spacer 3.4|4369639|21|NZ_CP043501|CRT matches to position: 4369807-4369827, mismatch: 0, identity: 1.0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

2. spacer 3.5|4369681|21|NZ_CP043501|CRT matches to position: 4369807-4369827, mismatch: 0, identity: 1.0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

3. spacer 3.6|4369723|21|NZ_CP043501|CRT matches to position: 4369807-4369827, mismatch: 0, identity: 1.0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

4. spacer 3.7|4369765|21|NZ_CP043501|CRT matches to position: 4369807-4369827, mismatch: 0, identity: 1.0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1857538 : 1913969

Bacillus_phage(24.49%)

terminase,capsid,plate,integrase,tRNA,tail,protease,holin,portal

attL 1867772:1867788|attR 1920119:1920135

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043054090.1\|1857538_1858015_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_020450324.1\|1857995_1858685_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_023855532.1\|1858697_1859156_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_026578976.1\|1859145_1860171_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.5e-67	42.2
WP_096747896.1\|1860409_1862335_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.1e-61	32.1
WP_048350303.1\|1862481_1862988_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_020450329.1\|1862991_1863636_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_020450330.1\|1863674_1863848_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_095293002.1\|1863854_1864631_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.4e-15	25.6
WP_020450332.1\|1864675_1864870_-	YdiK family protein	NA	NA	NA	NA
WP_020450333.1\|1864866_1865601_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003179248.1\|1865826_1866111_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	2.9e-19	52.7
WP_020450334.1\|1866155_1867790_+	chaperonin GroEL	A0A219YK78	uncultured_virus	4.8e-159	57.7
1867772:1867788	attL	NA	NA	NA	NA
WP_059231566.1\|1867867_1869079_-\|integrase	site-specific integrase	S6C485	Thermus_phage	1.9e-88	44.6
WP_043927786.1\|1869093_1869597_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	2.7e-52	59.5
WP_096747898.1\|1869686_1870352_-	hypothetical protein	NA	NA	NA	NA
WP_043927782.1\|1870833_1871196_-	helix-turn-helix transcriptional regulator	A8ASM2	Listeria_phage	7.4e-12	36.3
WP_043927783.1\|1871386_1871617_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003179259.1\|1871667_1871973_+	hypothetical protein	NA	NA	NA	NA
WP_043927784.1\|1871969_1872659_+	antirepressor	A0A0F6N3N8	Staphylococcus_phage	9.7e-37	51.3
WP_016886656.1\|1872723_1873287_+	helix-turn-helix transcriptional regulator	A0A2H4J884	uncultured_Caudovirales_phage	3.9e-60	55.1
WP_096747899.1\|1873288_1873546_+	hypothetical protein	NA	NA	NA	NA
WP_016886653.1\|1873746_1873938_+	hypothetical protein	NA	NA	NA	NA
WP_096747900.1\|1873934_1874846_+	hypothetical protein	A0A0A7RUE9	Clostridium_phage	2.1e-87	62.1
WP_073358662.1\|1874865_1875603_+	hypothetical protein	A0A0A7RVR3	Clostridium_phage	6.2e-58	46.9
WP_096747902.1\|1876365_1877319_+	ATP-binding protein	A0A0K2CPA5	Brevibacillus_phage	2.4e-57	51.1
WP_164906527.1\|1877318_1877462_+	hypothetical protein	NA	NA	NA	NA
WP_096747903.1\|1877769_1878036_+	hypothetical protein	A0A1P8CWX5	Bacillus_phage	6.6e-18	53.3
WP_149208558.1\|1878048_1878507_+	DUF1064 domain-containing protein	A0A2H4J891	uncultured_Caudovirales_phage	5.4e-52	69.3
WP_043929226.1\|1878713_1878920_+	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	9.0e-15	65.5
WP_096747905.1\|1878954_1879419_+	hypothetical protein	NA	NA	NA	NA
WP_043929229.1\|1879455_1879770_+	hypothetical protein	NA	NA	NA	NA
WP_096747906.1\|1879944_1880319_+	hypothetical protein	A0A0A7RWK2	Clostridium_phage	1.8e-13	36.6
WP_096747907.1\|1880315_1880684_+	hypothetical protein	A0A2H4JDM0	uncultured_Caudovirales_phage	3.1e-26	77.8
WP_096747908.1\|1880680_1880893_+	hypothetical protein	R4JF30	Bacillus_phage	3.3e-28	92.1
WP_149208559.1\|1880871_1881285_+	hypothetical protein	O64129	Bacillus_phage	8.6e-57	79.1
WP_059231593.1\|1881281_1881533_+	hypothetical protein	NA	NA	NA	NA
WP_016886634.1\|1881780_1882053_+	DUF5052 family protein	F8WQ63	Bacillus_phage	9.4e-28	70.3
WP_043929357.1\|1882067_1882334_+	hypothetical protein	A0A0H3UYW6	Geobacillus_virus	2.7e-11	61.1
WP_016886631.1\|1882416_1882569_+	hypothetical protein	NA	NA	NA	NA
WP_164906528.1\|1883077_1883221_+	hypothetical protein	A0A2H4JCE7	uncultured_Caudovirales_phage	2.3e-09	60.0
WP_043929419.1\|1883329_1883608_+	hypothetical protein	NA	NA	NA	NA
WP_043929420.1\|1883883_1884339_+	sigma-70 family RNA polymerase sigma factor	A0A2H4J4R7	uncultured_Caudovirales_phage	7.2e-65	80.1
WP_043929421.1\|1884512_1884725_+	hypothetical protein	NA	NA	NA	NA
WP_043929422.1\|1885103_1885832_+	hypothetical protein	A0A2P1JTW4	Anoxybacillus_phage	7.0e-62	56.2
WP_096747910.1\|1885831_1887124_+\|terminase	PBSX family phage terminase large subunit	A0A2P1JTW5	Anoxybacillus_phage	2.1e-162	71.7
WP_096747911.1\|1887127_1888666_+\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	1.4e-144	51.1
WP_096747912.1\|1888658_1889576_+	hypothetical protein	A0A1B1P7D7	Bacillus_phage	6.4e-52	39.1
WP_157765907.1\|1889650_1889827_+	hypothetical protein	NA	NA	NA	NA
WP_096747913.1\|1889879_1891055_+\|terminase	terminase	A0A1B1P7E4	Bacillus_phage	2.6e-82	52.6
WP_075178039.1\|1891067_1892003_+\|capsid	phage major capsid protein	A0A1B1P7E3	Bacillus_phage	8.6e-105	63.8
WP_096747914.1\|1892013_1892418_+	hypothetical protein	NA	NA	NA	NA
WP_096747915.1\|1892424_1892820_+	DUF3199 family protein	A0A1B1P7D6	Bacillus_phage	4.9e-17	39.5
WP_096747916.1\|1892816_1893173_+	YqbH/XkdH family protein	NA	NA	NA	NA
WP_144619780.1\|1893169_1893667_+	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	1.5e-39	47.2
WP_096747918.1\|1893656_1894121_+\|portal	phage portal protein	NA	NA	NA	NA
WP_096747919.1\|1894121_1894349_+	hypothetical protein	NA	NA	NA	NA
WP_096747920.1\|1894349_1895750_+\|tail	phage tail sheath protein	A0A0A7RTT5	Clostridium_phage	4.3e-84	41.8
WP_059231625.1\|1895751_1896195_+\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	1.2e-27	46.6
WP_016886607.1\|1896544_1896628_-	hypothetical protein	NA	NA	NA	NA
WP_096747921.1\|1896767_1897217_+\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	1.5e-09	31.2
WP_085959894.1\|1897246_1897396_+	hypothetical protein	NA	NA	NA	NA
WP_149208560.1\|1897399_1902661_+	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	3.8e-48	40.9
WP_017474907.1\|1902653_1903313_+	LysM peptidoglycan-binding domain-containing protein	A0A090DBR9	Clostridium_phage	1.3e-25	33.3
WP_017474908.1\|1903334_1904318_+	hypothetical protein	H7BV96	unidentified_phage	9.6e-38	31.6
WP_017474909.1\|1904314_1904623_+	DUF2577 domain-containing protein	S6C459	Thermus_phage	1.1e-05	36.3
WP_017474910.1\|1904635_1905061_+	DUF2634 domain-containing protein	A0A2H4J6K5	uncultured_Caudovirales_phage	8.7e-12	35.9
WP_017474911.1\|1905053_1906097_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	1.3e-72	44.6
WP_017474912.1\|1906083_1906662_+	YmfQ family protein	A0A0A7RTT8	Clostridium_phage	1.8e-15	27.8
WP_017474913.1\|1906658_1906934_+	hypothetical protein	NA	NA	NA	NA
WP_017474914.1\|1906934_1908038_+	hypothetical protein	M4ZRP1	Bacillus_phage	2.1e-17	63.4
WP_017474915.1\|1908049_1908379_+	hypothetical protein	A0A2H4JCI0	uncultured_Caudovirales_phage	1.1e-11	39.4
WP_017474916.1\|1908375_1908558_+	XkdX family protein	NA	NA	NA	NA
WP_149208561.1\|1908658_1909492_+	hypothetical protein	NA	NA	NA	NA
WP_017474918.1\|1909573_1909843_+	protein xhlA	A0A2H4JD40	uncultured_Caudovirales_phage	1.6e-24	61.8
WP_017474919.1\|1909858_1910122_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	1.4e-31	74.7
WP_096747928.1\|1910173_1911253_+	N-acetylmuramoyl-L-alanine amidase	D6QWM6	uncultured_phage	2.6e-44	40.8
WP_157765908.1\|1911260_1911407_+	hypothetical protein	NA	NA	NA	NA
WP_149208562.1\|1911531_1912506_-	Abi family protein	NA	NA	NA	NA
WP_096747930.1\|1912938_1913112_-	hypothetical protein	A0A1P8CWV7	Bacillus_phage	3.1e-24	90.9
WP_096747931.1\|1913159_1913969_-	ATP-dependent DNA ligase	O64130	Bacillus_phage	4.0e-98	62.8
1920119:1920135	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1989180 : 1999105

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043054145.1\|1989180_1990476_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	5.9e-19	27.1
WP_075213470.1\|1990550_1991267_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3G7P8	Synechococcus_phage	3.3e-48	43.7
WP_003179532.1\|1991268_1991523_+	phosphoribosylformylglycinamidine synthase subunit PurS	M4QPE7	Synechococcus_phage	8.0e-05	33.3
WP_043054147.1\|1991519_1992203_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_043054148.1\|1992186_1994415_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.8e-159	41.8
WP_149208563.1\|1994390_1995821_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.4e-52	32.9
WP_035337048.1\|1995945_1996986_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.7e-62	46.3
WP_035337045.1\|1996982_1997570_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-28	38.9
WP_035337043.1\|1997566_1999105_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	5.6e-77	52.0

DBSCAN-SWA_3

2229905 : 2294192

Bacillus_phage(42.86%)

head,terminase,portal,capsid,plate,integrase,transposase,tRNA,tail,holin,coat,protease

attL 2229867:2229889|attR 2272007:2272029

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2229867:2229889	attL	NA	NA	NA	NA
WP_043054197.1\|2229905_2231024_-\|integrase	site-specific integrase	Q5YAA6	Bacillus_phage	7.6e-124	60.8
WP_043054198.1\|2231038_2231485_-	ImmA/IrrE family metallo-endopeptidase	A0A2I7SC21	Paenibacillus_phage	2.5e-41	54.1
WP_043054199.1\|2231488_2231830_-	helix-turn-helix transcriptional regulator	A0A2I7SC14	Paenibacillus_phage	1.6e-32	62.8
WP_052500258.1\|2231998_2232250_+	helix-turn-helix transcriptional regulator	A0A2I7SC17	Paenibacillus_phage	1.3e-26	72.2
WP_043054201.1\|2232605_2233307_+	Rha family transcriptional regulator	A0A0S2MVD8	Bacillus_phage	9.4e-88	70.4
WP_043054202.1\|2233502_2234054_-	hypothetical protein	NA	NA	NA	NA
WP_043054203.1\|2234111_2234330_+	hypothetical protein	NA	NA	NA	NA
WP_043054204.1\|2234322_2235165_+	replication protein	V9QKF6	Oenococcus_phage	4.5e-52	43.9
WP_043054205.1\|2235124_2235973_+	ATP-binding protein	Q9MBR8	Staphylococcus_prophage	5.2e-24	32.3
WP_155392279.1\|2235962_2236121_+	hypothetical protein	NA	NA	NA	NA
WP_052500259.1\|2236272_2236821_+	hypothetical protein	A0A0K2CNP4	Brevibacillus_phage	4.0e-09	43.3
WP_113742868.1\|2236925_2237075_+	BH0509 family protein	NA	NA	NA	NA
WP_043054206.1\|2237146_2237347_+	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	3.6e-08	50.0
WP_043054207.1\|2237382_2237616_+	hypothetical protein	NA	NA	NA	NA
WP_155392280.1\|2237827_2237965_+	hypothetical protein	NA	NA	NA	NA
WP_043054209.1\|2238005_2238320_+	hypothetical protein	NA	NA	NA	NA
WP_043054210.1\|2238316_2238565_+	hypothetical protein	NA	NA	NA	NA
WP_043054211.1\|2238604_2238916_+	hypothetical protein	NA	NA	NA	NA
WP_043054212.1\|2238947_2239160_+	hypothetical protein	NA	NA	NA	NA
WP_043054213.1\|2239156_2239339_+	hypothetical protein	NA	NA	NA	NA
WP_043054214.1\|2239520_2239787_+	hypothetical protein	A0A2H4JDM6	uncultured_Caudovirales_phage	3.5e-11	39.1
WP_043054215.1\|2240072_2240513_+	ArpU family transcriptional regulator	S6AVV9	Thermus_phage	1.4e-36	51.8
WP_043054216.1\|2240512_2241055_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	4.3e-56	60.6
WP_043054217.1\|2241288_2241480_+	hypothetical protein	NA	NA	NA	NA
WP_075213432.1\|2241885_2242110_+\|coat	spore coat protein	NA	NA	NA	NA
WP_043054218.1\|2242363_2243032_+	hypothetical protein	NA	NA	NA	NA
WP_043054565.1\|2243098_2243416_+	hypothetical protein	NA	NA	NA	NA
WP_043054219.1\|2243442_2243817_+	HNH endonuclease	A0A1U7Q1S7	Geobacillus_virus	6.9e-29	51.7
WP_043054220.1\|2244047_2244563_+\|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	9.8e-34	45.2
WP_043054221.1\|2244559_2246269_+\|terminase	terminase large subunit	W8CZ43	Bacillus_phage	2.5e-211	64.1
WP_035316082.1\|2246281_2246473_+	DUF1056 family protein	NA	NA	NA	NA
WP_043054222.1\|2246473_2247784_+\|portal	phage portal protein	D6R3Y6	Bacillus_phage	2.4e-105	46.1
WP_035338281.1\|2247728_2248460_+\|protease	Clp protease ClpP	A0A0B5A796	Paenibacillus_phage	2.4e-57	56.9
WP_043054223.1\|2248499_2249780_+\|capsid	phage major capsid protein	A0A288WGE9	Bacillus_phage	6.3e-74	43.5
WP_052500260.1\|2249803_2250247_+	hypothetical protein	NA	NA	NA	NA
WP_043054224.1\|2250261_2250564_+\|head,tail	phage gp6-like head-tail connector protein	A0A0S2GLH6	Bacillus_phage	7.3e-13	46.3
WP_043054225.1\|2250553_2250862_+\|head	phage head closure protein	A0A2H4JCB1	uncultured_Caudovirales_phage	9.7e-13	38.6
WP_043054226.1\|2250861_2251260_+	hypothetical protein	NA	NA	NA	NA
WP_043054227.1\|2251256_2251640_+	phage protein	NA	NA	NA	NA
WP_043054228.1\|2251654_2252272_+\|tail	tail protein	NA	NA	NA	NA
WP_043054229.1\|2252325_2252691_+	hypothetical protein	NA	NA	NA	NA
WP_096747970.1\|2252899_2257369_+\|tail	phage tail tape measure protein	A6M961	Geobacillus_virus	1.1e-69	42.1
WP_075213433.1\|2257368_2258205_+\|tail	phage tail family protein	D6R3Z9	Bacillus_phage	2.0e-108	67.9
WP_075213434.1\|2258217_2259930_+	alkaline phosphatase	D6R400	Bacillus_phage	5.3e-217	65.7
WP_075213875.1\|2259966_2262612_+	peptidase G2	D6R401	Bacillus_phage	2.0e-292	56.8
WP_165688281.1\|2262622_2263942_+\|plate	BppU family phage baseplate upper protein	D6R402	Bacillus_phage	9.1e-68	43.3
WP_075213437.1\|2263954_2264278_+	hypothetical protein	M4ZR44	Bacillus_phage	1.7e-12	46.4
WP_075213438.1\|2264274_2264457_+	XkdX family protein	A0EWM9	Staphylococcus_virus	1.4e-06	47.9
WP_075213459.1\|2264519_2264789_+	protein xhlA	A0A2H4JD40	uncultured_Caudovirales_phage	2.1e-24	61.8
WP_003185319.1\|2264804_2265068_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	2.0e-30	73.6
WP_065644215.1\|2265115_2266069_+	LysM peptidoglycan-binding domain-containing protein	A0A141HSE6	Bacillus_phage	3.9e-60	41.7
WP_016886588.1\|2266169_2266505_-	hypothetical protein	NA	NA	NA	NA
WP_071583950.1\|2266522_2268046_-\|transposase	transposase	A0A1L2JY53	Aeribacillus_phage	1.2e-07	36.6
WP_071583847.1\|2268301_2269423_+	tetratricopeptide repeat protein	A0A1P8CWN8	Bacillus_phage	2.4e-53	35.1
WP_071583848.1\|2269645_2269966_-	YolD-like family protein	O64030	Bacillus_phage	2.5e-11	36.9
WP_075213440.1\|2270103_2270916_-	hypothetical protein	NA	NA	NA	NA
WP_031305060.1\|2271136_2271355_+	transcriptional regulator	NA	NA	NA	NA
WP_075213783.1\|2271379_2271694_-	DUF1827 family protein	NA	NA	NA	NA
WP_025811885.1\|2272478_2273804_+	TGS domain-containing protein	NA	NA	NA	NA
2272007:2272029	attR	NA	NA	NA	NA
WP_043054245.1\|2274025_2276833_+	hypothetical protein	NA	NA	NA	NA
WP_080131295.1\|2277054_2277570_-	HXXEE domain-containing protein	NA	NA	NA	NA
WP_023856463.1\|2277679_2278249_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_031305076.1\|2278376_2279141_+	type I 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_096748451.1\|2279492_2281268_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_025811874.1\|2281469_2282237_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.7e-30	37.0
WP_096747971.1\|2282233_2283247_+	aliphatic sulfonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_020450657.1\|2283243_2284080_+	ABC transporter permease	NA	NA	NA	NA
WP_020450658.1\|2284093_2285224_+	FMNH2-dependent alkanesulfonate monooxygenase	NA	NA	NA	NA
WP_020450659.1\|2285254_2285713_-	hypothetical protein	NA	NA	NA	NA
WP_020450660.1\|2285709_2285916_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020450662.1\|2286465_2286678_+	hypothetical protein	NA	NA	NA	NA
WP_020450663.1\|2286784_2287531_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	5.4e-09	23.3
WP_031305077.1\|2287496_2288966_+	hypothetical protein	NA	NA	NA	NA
WP_020450665.1\|2288955_2289864_+	PqqD family protein	NA	NA	NA	NA
WP_011197680.1\|2289860_2290145_+	hypothetical protein	NA	NA	NA	NA
WP_023856470.1\|2290251_2290521_+	30S ribosomal protein S14	NA	NA	NA	NA
WP_149208565.1\|2290846_2291476_-	hypothetical protein	NA	NA	NA	NA
WP_020450668.1\|2291556_2292705_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_025811863.1\|2292768_2293671_+	amidase domain-containing protein	NA	NA	NA	NA
WP_020450670.1\|2293718_2294192_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA

DBSCAN-SWA_4

2624213 : 2699697

uncultured_Caudovirales_phage(25.64%)

terminase,capsid,plate,tail,holin,coat,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023856676.1\|2624213_2624663_-\|coat	spore coat protein	NA	NA	NA	NA
WP_003180694.1\|2624813_2625296_-\|coat	spore coat protein	NA	NA	NA	NA
WP_003180696.1\|2625428_2625935_-\|coat	spore coat protein	NA	NA	NA	NA
WP_003180698.1\|2626002_2626356_-	hypothetical protein	NA	NA	NA	NA
WP_003180700.1\|2626404_2626791_-\|coat	spore coat protein	NA	NA	NA	NA
WP_003180704.1\|2626938_2627295_+	DUF1360 domain-containing protein	NA	NA	NA	NA
WP_003180706.1\|2627581_2627791_+	hypothetical protein	NA	NA	NA	NA
WP_020450965.1\|2627870_2628002_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_003180710.1\|2628128_2628386_+	sporulation protein	NA	NA	NA	NA
WP_059261123.1\|2628424_2630704_-	ATP-dependent helicase	A0A068EQC7	Bacillus_phage	6.6e-90	35.5
WP_003180714.1\|2630825_2631083_+	hypothetical protein	NA	NA	NA	NA
WP_003180716.1\|2631122_2631710_-	DedA family protein	NA	NA	NA	NA
WP_003180718.1\|2631805_2632792_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.6e-53	38.1
WP_167511163.1\|2632788_2633685_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.9e-85	56.7
WP_020450971.1\|2633701_2634097_-	GtrA family protein	NA	NA	NA	NA
WP_096748011.1\|2634262_2634682_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003180728.1\|2634691_2635201_-	hypothetical protein	NA	NA	NA	NA
WP_003180731.1\|2635265_2635988_-	esterase family protein	NA	NA	NA	NA
WP_003180732.1\|2636099_2636555_-	hypothetical protein	NA	NA	NA	NA
WP_003180734.1\|2636566_2637055_-	DNA damage-inducible protein DinB	NA	NA	NA	NA
WP_003180735.1\|2637135_2638083_-	YafY family transcriptional regulator	NA	NA	NA	NA
WP_003180736.1\|2638392_2639517_+	methionine biosynthesis PLP-dependent protein	A0A0B5JD48	Pandoravirus	9.0e-16	25.6
WP_035338954.1\|2639506_2640682_+	cystathionine beta-lyase	A0A0B5JD48	Pandoravirus	4.8e-20	28.0
WP_035338952.1\|2640726_2641917_-	DUF819 domain-containing protein	NA	NA	NA	NA
WP_035338950.1\|2642088_2642658_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003180743.1\|2642647_2642932_+	hypothetical protein	NA	NA	NA	NA
WP_065643372.1\|2643109_2644483_+	serine hydrolase	A0A1D8EXR7	Mycobacterium_phage	7.7e-09	24.6
WP_065643371.1\|2645084_2646035_-	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_033155145.1\|2646653_2646737_-	hypothetical protein	NA	NA	NA	NA
WP_020450980.1\|2647064_2647397_-	hypothetical protein	NA	NA	NA	NA
WP_020450981.1\|2647408_2648851_-	hypothetical protein	NA	NA	NA	NA
WP_020450982.1\|2648904_2649243_+	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_044805482.1\|2649320_2649497_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020450984.1\|2649840_2650110_+	phage-like protein XhlA	A0A2H4JD40	uncultured_Caudovirales_phage	3.7e-24	62.9
WP_020450985.1\|2650125_2650389_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	1.5e-30	77.0
WP_020450986.1\|2650440_2651520_+	N-acetylmuramoyl-L-alanine amidase	D6QWM6	uncultured_phage	2.9e-43	40.4
WP_026579880.1\|2651554_2651743_-	hypothetical protein	NA	NA	NA	NA
WP_026579879.1\|2651761_2652577_-	GAF domain-containing protein	NA	NA	NA	NA
WP_020450988.1\|2652685_2652868_-	hypothetical protein	NA	NA	NA	NA
WP_011197793.1\|2653309_2653489_+	hypothetical protein	NA	NA	NA	NA
WP_020450989.1\|2653526_2654105_+	maltose O-acetyltransferase Maa	NA	NA	NA	NA
WP_020450990.1\|2654187_2654475_-	hypothetical protein	NA	NA	NA	NA
WP_020450991.1\|2654683_2655574_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_096748012.1\|2655891_2657721_+	assimilatory sulfite reductase (NADPH) flavoprotein subunit	NA	NA	NA	NA
WP_020450993.1\|2657748_2659467_+	assimilatory sulfite reductase (NADPH) hemoprotein subunit	NA	NA	NA	NA
WP_023856699.1\|2659522_2660410_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_023856700.1\|2660501_2661374_+	DMT family transporter	NA	NA	NA	NA
WP_023856701.1\|2661422_2661800_+	glyoxalase	NA	NA	NA	NA
WP_023856702.1\|2661844_2662393_-	hypothetical protein	NA	NA	NA	NA
WP_020450998.1\|2662832_2663573_+	LysM peptidoglycan-binding domain-containing protein	A0A217ER34	Bacillus_phage	2.7e-29	57.6
WP_051143313.1\|2663630_2665055_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_020451000.1\|2665071_2665650_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_023856707.1\|2666025_2666439_-	hypothetical protein	NA	NA	NA	NA
WP_035338945.1\|2666811_2667294_-	DUF600 family protein	NA	NA	NA	NA
WP_020451003.1\|2667782_2668430_+	poly-gamma-glutamate hydrolase family protein	A0A0Y0AJU6	Bacillus_phage	2.6e-44	46.5
WP_020451004.1\|2668442_2669099_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	6.8e-40	49.7
WP_020451005.1\|2669286_2669640_-	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	3.6e-19	49.6
WP_023856709.1\|2669812_2670073_+	helix-turn-helix transcriptional regulator	S5MA07	Brevibacillus_phage	3.0e-07	43.8
WP_033155144.1\|2670062_2670359_+	hypothetical protein	NA	NA	NA	NA
WP_023856711.1\|2670359_2671184_+\|portal	phage portal protein	S6BFM4	Thermus_phage	2.1e-25	29.6
WP_025811606.1\|2671083_2671884_+	ATP-binding protein	Q0H276	Geobacillus_phage	8.0e-59	47.7
WP_023856713.1\|2671883_2672054_+	hypothetical protein	NA	NA	NA	NA
WP_023856714.1\|2672153_2672495_+	hypothetical protein	NA	NA	NA	NA
WP_020451011.1\|2672491_2672695_+	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	6.4e-13	56.2
WP_080131330.1\|2672812_2673316_+	sigma-70 family RNA polymerase sigma factor	A0A0K2CNQ1	Brevibacillus_phage	4.9e-22	39.3
WP_026579866.1\|2673460_2674261_+\|terminase	terminase	A0A0S2MVB6	Bacillus_phage	2.6e-65	51.4
WP_080131331.1\|2674257_2675556_+\|terminase	PBSX family phage terminase large subunit	M4ZRM5	Bacillus_phage	1.1e-150	61.5
WP_020451015.1\|2675559_2677074_+\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	6.4e-142	55.3
WP_020451016.1\|2677081_2677930_+	hypothetical protein	A0A1B1P7E4	Bacillus_phage	8.8e-56	60.6
WP_020451017.1\|2677947_2678883_+\|capsid	phage capsid protein	A0A1B1P7E3	Bacillus_phage	3.6e-103	64.1
WP_023856716.1\|2678998_2679373_+	DUF3199 family protein	NA	NA	NA	NA
WP_026579862.1\|2679369_2679726_+	YqbH/XkdH family protein	NA	NA	NA	NA
WP_080131332.1\|2679722_2680211_+	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	1.1e-34	43.3
WP_035338940.1\|2680223_2680664_+	hypothetical protein	NA	NA	NA	NA
WP_020451022.1\|2680664_2680889_+	hypothetical protein	NA	NA	NA	NA
WP_080131333.1\|2680888_2682235_+\|tail	phage tail sheath protein	S5MNC1	Brevibacillus_phage	5.3e-79	40.2
WP_003180830.1\|2682236_2682680_+\|tail	phage tail tube protein	A0A0K2CNG3	Brevibacillus_phage	2.1e-24	44.7
WP_023856720.1\|2682844_2683294_+\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	4.1e-12	38.7
WP_095290311.1\|2683335_2683473_+	hypothetical protein	NA	NA	NA	NA
WP_149208569.1\|2683476_2687241_+	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	3.4e-43	48.1
WP_095290092.1\|2687233_2687890_+	LysM peptidoglycan-binding domain-containing protein	A0A090DBR9	Clostridium_phage	4.0e-24	32.6
WP_095290094.1\|2687946_2688927_+\|portal	phage portal protein	H7BV96	unidentified_phage	3.0e-39	31.7
WP_023856723.1\|2688923_2689232_+	DUF2577 domain-containing protein	S6C459	Thermus_phage	1.4e-06	37.3
WP_096748013.1\|2689250_2689676_+	DUF2634 domain-containing protein	A0A2H4J6K5	uncultured_Caudovirales_phage	1.6e-13	37.3
WP_096748014.1\|2689668_2690712_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	5.3e-71	43.5
WP_020451034.1\|2691621_2692008_+	phage protein	NA	NA	NA	NA
WP_096748016.1\|2692023_2693232_+	hypothetical protein	A0A2H4J4R1	uncultured_Caudovirales_phage	1.2e-21	42.9
WP_096748017.1\|2693273_2694233_+	hypothetical protein	A0A2H4J4R1	uncultured_Caudovirales_phage	1.8e-09	26.0
WP_035338928.1\|2694276_2694546_+	protein xhlA	A0A2H4JD40	uncultured_Caudovirales_phage	9.6e-25	65.2
WP_026579849.1\|2694560_2694824_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	3.1e-28	67.8
WP_096748018.1\|2694876_2695941_+	N-acetylmuramoyl-L-alanine amidase	S6BFI4	Thermus_phage	5.1e-45	52.0
WP_023856728.1\|2696039_2696726_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023856729.1\|2696738_2697755_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_025811596.1\|2697775_2698873_+	mannonate dehydratase	NA	NA	NA	NA
WP_023856787.1\|2698848_2699697_+	SDR family oxidoreductase	M1NMS3	Moumouvirus	5.6e-10	33.3

DBSCAN-SWA_5

2772542 : 2853074

104

Bacillus_phage(30.43%)

head,terminase,capsid,integrase,transposase,tail,protease,holin,portal

attL 2766314:2766329|attR 2821976:2821991

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2766314:2766329	attL	NA	NA	NA	NA
WP_144583092.1\|2772542_2773682_-\|integrase	tyrosine-type recombinase/integrase	S6C485	Thermus_phage	3.3e-66	39.4
WP_069500420.1\|2773713_2774193_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	2.3e-29	41.9
WP_025805709.1\|2774303_2774954_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.7e-30	48.9
WP_149208570.1\|2775033_2775300_-	hypothetical protein	NA	NA	NA	NA
WP_149208571.1\|2775536_2775899_-	helix-turn-helix domain-containing protein	A0A0A7RTK4	Clostridium_phage	7.4e-12	45.2
WP_149208572.1\|2776050_2776269_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167511153.1\|2776279_2776456_+	hypothetical protein	NA	NA	NA	NA
WP_011197842.1\|2776698_2777025_+	hypothetical protein	S6C476	Thermus_phage	2.8e-18	53.2
WP_125150311.1\|2777064_2777475_+	hypothetical protein	NA	NA	NA	NA
WP_011197844.1\|2777487_2778222_+	Rha family transcriptional regulator	A0A2I7SCU0	Paenibacillus_phage	4.5e-32	39.5
WP_009328672.1\|2778294_2778813_+	helix-turn-helix transcriptional regulator	A0A290FZK9	Caldibacillus_phage	9.8e-34	46.4
WP_011197845.1\|2778809_2779088_+	hypothetical protein	Q9ZXC9	Bacillus_phage	3.9e-21	51.7
WP_149208573.1\|2779465_2780404_+	hypothetical protein	S6C475	Thermus_phage	1.2e-82	49.4
WP_149208574.1\|2780421_2781243_+	recombination protein RecT	Q0H279	Geobacillus_phage	5.0e-80	57.5
WP_137736115.1\|2781949_2782930_+	ATP-binding protein	A6XMI1	Bacillus_virus	2.6e-59	50.6
WP_009328666.1\|2783024_2783228_+	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	1.3e-13	57.6
WP_009328665.1\|2783241_2783406_+	hypothetical protein	NA	NA	NA	NA
WP_009328664.1\|2783405_2783624_+	hypothetical protein	NA	NA	NA	NA
WP_077735854.1\|2783616_2783907_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_016885851.1\|2783903_2784116_+	hypothetical protein	U5PTT2	Bacillus_phage	3.6e-11	60.0
WP_025805718.1\|2784290_2784758_+	hypothetical protein	R4JMS5	Bacillus_phage	4.1e-39	95.0
WP_025805719.1\|2784754_2785153_+	hypothetical protein	R4JKA5	Bacillus_phage	3.1e-72	94.7
WP_025805720.1\|2785149_2785572_+	RusA family crossover junction endodeoxyribonuclease	M4ZS69	Bacillus_phage	7.2e-35	55.7
WP_149208576.1\|2785550_2785757_+	hypothetical protein	NA	NA	NA	NA
WP_149208577.1\|2785814_2786030_+	hypothetical protein	NA	NA	NA	NA
WP_149208578.1\|2786019_2786679_+	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	1.4e-21	74.3
WP_149208609.1\|2786614_2786824_+	hypothetical protein	A0A2H4JDM6	uncultured_Caudovirales_phage	1.8e-15	63.9
WP_149208579.1\|2786820_2787072_+	hypothetical protein	NA	NA	NA	NA
WP_149208580.1\|2787071_2787338_+	hypothetical protein	A0A0H3UYW6	Geobacillus_virus	1.9e-09	55.6
WP_149208581.1\|2787504_2787819_+	hypothetical protein	NA	NA	NA	NA
WP_149208582.1\|2787853_2788039_+	hypothetical protein	NA	NA	NA	NA
WP_149208583.1\|2788035_2788473_+	hypothetical protein	A0A2H4J8A0	uncultured_Caudovirales_phage	8.5e-55	74.3
WP_130569330.1\|2788517_2788712_+	hypothetical protein	A0A249XXE0	Clostridium_phage	2.0e-08	51.9
WP_167511154.1\|2788740_2788899_+	hypothetical protein	NA	NA	NA	NA
WP_075646937.1\|2789115_2789571_+	hypothetical protein	A0A290FZR5	Caldibacillus_phage	1.1e-41	61.2
WP_021837352.1\|2790373_2790604_+	hypothetical protein	NA	NA	NA	NA
WP_145930134.1\|2790797_2791613_+\|terminase	terminase small subunit	Q5YA77	Bacillus_phage	3.5e-78	64.3
WP_035333902.1\|2791609_2792887_+\|terminase	PBSX family phage terminase large subunit	A0A2P1JTW5	Anoxybacillus_phage	3.4e-152	69.0
WP_149208584.1\|2792883_2794299_+\|portal	phage portal protein	A0A2H4J4Q7	uncultured_Caudovirales_phage	2.7e-150	61.4
WP_149208585.1\|2794282_2795200_+\|capsid	minor capsid protein	A0A1Q1PVS0	Bacillus_phage	4.0e-86	53.7
WP_149208586.1\|2795201_2795531_+	hypothetical protein	NA	NA	NA	NA
WP_149208587.1\|2795532_2796177_+	hypothetical protein	U5PTS2	Bacillus_phage	2.0e-20	51.7
WP_155761920.1\|2796218_2796371_+	hypothetical protein	NA	NA	NA	NA
WP_075218721.1\|2796481_2797063_+	DUF4355 domain-containing protein	A0A2H4J4P4	uncultured_Caudovirales_phage	9.3e-49	52.8
WP_149208588.1\|2797076_2798000_+\|capsid	phage major capsid protein	A0A2H4JCG0	uncultured_Caudovirales_phage	8.8e-110	64.8
WP_009328639.1\|2798003_2798342_+	hypothetical protein	NA	NA	NA	NA
WP_009328638.1\|2798343_2798613_+	hypothetical protein	NA	NA	NA	NA
WP_009328637.1\|2798626_2798935_+	hypothetical protein	A0A1W6JQJ1	Staphylococcus_phage	2.5e-13	44.0
WP_149208589.1\|2798934_2799276_+\|head	phage head closure protein	NA	NA	NA	NA
WP_016885817.1\|2799275_2799680_+	HK97 gp10 family phage protein	O48447	Bacillus_phage	3.2e-40	62.5
WP_025807714.1\|2799676_2800090_+	DUF3168 domain-containing protein	A0A0C5AEH4	Paenibacillus_phage	2.7e-10	38.3
WP_021837398.1\|2800102_2800648_+\|tail	phage major tail protein, TP901-1 family	Q597U9	Lactobacillus_virus	1.0e-17	31.4
WP_144602386.1\|2800538_2800910_+	fibronectin type III domain-containing protein	R4JF61	Bacillus_phage	4.1e-26	71.1
WP_003179339.1\|2800977_2801475_+	hypothetical protein	NA	NA	NA	NA
WP_009328631.1\|2801492_2801834_+	hypothetical protein	NA	NA	NA	NA
WP_149208590.1\|2801838_2804901_+	hypothetical protein	Q4ZC60	Staphylococcus_virus	4.4e-49	28.7
WP_149208591.1\|2804897_2805701_+\|tail	phage tail family protein	NA	NA	NA	NA
WP_149208592.1\|2805713_2809232_+	hypothetical protein	Q5YA57	Bacillus_phage	8.8e-126	46.2
WP_009328627.1\|2809245_2809545_+	hypothetical protein	NA	NA	NA	NA
WP_009328626.1\|2809607_2809877_+	protein xhlA	A0A2H4JD40	uncultured_Caudovirales_phage	3.8e-21	58.4
WP_009328625.1\|2809892_2810156_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	3.6e-32	75.9
WP_009328623.1\|2811131_2811467_-	hypothetical protein	NA	NA	NA	NA
WP_009328622.1\|2811492_2813007_-\|transposase	transposase	NA	NA	NA	NA
WP_009328620.1\|2813572_2813818_+	helix-turn-helix domain-containing protein	A0A2H4JDR0	uncultured_Caudovirales_phage	9.7e-24	69.6
WP_129093992.1\|2813939_2814575_+	DUF4065 domain-containing protein	NA	NA	NA	NA
WP_009328618.1\|2814561_2814981_+	hypothetical protein	NA	NA	NA	NA
WP_020451114.1\|2815277_2815610_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_096748033.1\|2815801_2815957_+	hypothetical protein	NA	NA	NA	NA
WP_020451116.1\|2816061_2816241_+	hypothetical protein	NA	NA	NA	NA
WP_020451117.1\|2816414_2816876_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_075213199.1\|2816881_2818732_-	DNA ligase D	NA	NA	NA	NA
WP_026579818.1\|2818735_2819608_-	Ku protein	A0A218M9C0	Mycobacterium_phage	1.0e-38	34.3
WP_075213200.1\|2819756_2821409_-	diguanylate cyclase	NA	NA	NA	NA
WP_149208593.1\|2821697_2822339_+	DedA family protein	NA	NA	NA	NA
2821976:2821991	attR	NA	NA	NA	NA
WP_020451122.1\|2822611_2823379_+	TerC family protein	A0A068EP98	Bacillus_phage	1.8e-31	44.4
WP_023856784.1\|2823674_2824433_+	RNA polymerase sigma factor SigI	NA	NA	NA	NA
WP_023856785.1\|2824429_2825518_+	anti-sigma factor domain-containing protein	NA	NA	NA	NA
WP_020451125.1\|2825530_2825728_-	alpha/beta-type small acid-soluble spore protein	A0A1P8CX76	Bacillus_phage	4.0e-12	62.1
WP_023856786.1\|2825858_2826578_-	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_020451127.1\|2826719_2827613_+\|protease	protease HtpX	NA	NA	NA	NA
WP_020451128.1\|2827761_2829111_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_075213202.1\|2829222_2831223_+	penicillin-binding transpeptidase domain-containing protein	NA	NA	NA	NA
WP_149208594.1\|2831244_2832675_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	9.4e-119	47.7
WP_023856450.1\|2832818_2833034_+	hypothetical protein	NA	NA	NA	NA
WP_020451131.1\|2833030_2833213_+	hypothetical protein	NA	NA	NA	NA
WP_025810280.1\|2833475_2834501_-	acyltransferase family protein	NA	NA	NA	NA
WP_020451133.1\|2834810_2837021_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_020451134.1\|2837028_2837526_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y3R2	Acanthamoeba_polyphaga_mimivirus	2.4e-21	51.4
WP_023857318.1\|2837737_2838799_-	S-methyl-5-thioribose-1-phosphate isomerase	NA	NA	NA	NA
WP_096748035.1\|2838804_2840001_-	S-methyl-5-thioribose kinase	NA	NA	NA	NA
WP_020451137.1\|2840310_2841090_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_096748036.1\|2841185_2842376_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_142368374.1\|2842608_2843826_+	2,3-diketo-5-methylthiopentyl-1-phosphate enolase	NA	NA	NA	NA
WP_096748038.1\|2843822_2844521_+	2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase	NA	NA	NA	NA
WP_023857315.1\|2844481_2845108_+	methylthioribulose 1-phosphate dehydratase	NA	NA	NA	NA
WP_096748039.1\|2845123_2845660_+	cupin domain-containing protein	NA	NA	NA	NA
WP_096748040.1\|2845687_2846152_-	metallothiol transferase FosB	Q2LI91	Bacillus_phage	2.4e-31	53.4
WP_020451144.1\|2846138_2846459_-	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_020451145.1\|2846674_2846917_+	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_020451146.1\|2846975_2848487_-	sensor histidine kinase	NA	NA	NA	NA
WP_020451147.1\|2848724_2849180_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_020451148.1\|2849203_2849983_-	flagellar motor protein MotB	NA	NA	NA	NA
WP_020451149.1\|2849975_2850779_-	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_096748041.1\|2850977_2853074_-\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	6.2e-127	40.8

DBSCAN-SWA_6

3804894 : 3816538

Staphylococcus_phage(55.56%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023857488.1\|3804894_3805488_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.6e-14	37.6
WP_023857489.1\|3805477_3806233_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	6.1e-08	24.7
WP_003183108.1\|3806415_3806511_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_096748206.1\|3806630_3807152_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_020452011.1\|3807162_3807537_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003183115.1\|3807638_3808103_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.7e-45	70.7
WP_020452012.1\|3808137_3809334_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.6e-116	54.2
WP_020452013.1\|3809355_3810003_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.2e-40	43.4
WP_023857492.1\|3810014_3811103_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.2e-62	37.2
WP_020452015.1\|3811464_3811809_-	hypothetical protein	NA	NA	NA	NA
WP_096748207.1\|3812075_3814265_-	AAA family ATPase	A0A220BYT7	Staphylococcus_phage	1.3e-154	41.9
WP_023857494.1\|3814481_3814751_-	hypothetical protein	NA	NA	NA	NA
WP_023857495.1\|3814740_3815871_-	tetratricopeptide repeat protein	A0A1P8CWN8	Bacillus_phage	1.8e-72	41.2
WP_020452019.1\|3816100_3816538_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	9.2e-17	44.6

DBSCAN-SWA_7

4001077 : 4056254

Bacillus_phage(32.5%)

terminase,capsid,plate,integrase,tail,holin,coat,portal

attL 4012498:4012512|attR 4042813:4042827

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048349970.1\|4001077_4001872_-\|coat	spore coat protein	NA	NA	NA	NA
WP_065644169.1\|4001944_4002529_-	signal peptidase I	NA	NA	NA	NA
WP_020452169.1\|4002525_4003254_-	amyloid fiber anchoring/assembly protein TapA	NA	NA	NA	NA
WP_023855188.1\|4003531_4003852_+	YqzG/YhdC family protein	NA	NA	NA	NA
WP_025811164.1\|4003881_4004064_-	YqzE family protein	NA	NA	NA	NA
WP_025811163.1\|4004152_4004518_-	chromosome partitioning protein ParA	NA	NA	NA	NA
WP_025811162.1\|4004529_4004910_-	ComGF family competence protein	NA	NA	NA	NA
WP_025811161.1\|4004926_4005274_-	hypothetical protein	NA	NA	NA	NA
WP_026579312.1\|4005257_4005695_-	type II secretion system protein	NA	NA	NA	NA
WP_096748222.1\|4005700_4005964_-	competence protein ComG	NA	NA	NA	NA
WP_080624021.1\|4006089_4006779_+	hypothetical protein	NA	NA	NA	NA
WP_080624022.1\|4006945_4007686_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_080624023.1\|4007785_4008850_-	hypothetical protein	NA	NA	NA	NA
WP_096748465.1\|4008875_4009232_-	hypothetical protein	D2XQ01	Bacillus_virus	3.9e-13	38.3
WP_080624025.1\|4009475_4010333_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_016886590.1\|4010412_4011273_+	hypothetical protein	NA	NA	NA	NA
WP_080624026.1\|4011312_4012386_-	N-acetylmuramoyl-L-alanine amidase	D6QWM6	uncultured_phage	1.5e-44	41.2
WP_080624027.1\|4012437_4012701_-\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	2.0e-30	75.9
4012498:4012512	attL	NA	NA	NA	NA
WP_020450984.1\|4012716_4012986_-	phage-like protein XhlA	A0A2H4JD40	uncultured_Caudovirales_phage	3.7e-24	62.9
WP_080624028.1\|4013065_4013899_-	hypothetical protein	NA	NA	NA	NA
WP_043929126.1\|4014000_4014183_-	XkdX family protein	A0A2H4JAA1	uncultured_Caudovirales_phage	3.7e-12	57.4
WP_017474915.1\|4014179_4014509_-	hypothetical protein	A0A2H4JCI0	uncultured_Caudovirales_phage	1.1e-11	39.4
WP_017474914.1\|4014520_4015624_-	hypothetical protein	M4ZRP1	Bacillus_phage	2.1e-17	63.4
WP_017474913.1\|4015624_4015900_-	hypothetical protein	NA	NA	NA	NA
WP_017474912.1\|4015896_4016475_-	YmfQ family protein	A0A0A7RTT8	Clostridium_phage	1.8e-15	27.8
WP_017474911.1\|4016461_4017505_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	1.3e-72	44.6
WP_017474910.1\|4017497_4017923_-	DUF2634 domain-containing protein	A0A2H4J6K5	uncultured_Caudovirales_phage	8.7e-12	35.9
WP_149208604.1\|4017935_4018244_-	DUF2577 family protein	S6C459	Thermus_phage	1.5e-05	36.3
WP_080624033.1\|4018240_4019224_-\|portal	phage portal protein	H7BV96	unidentified_phage	3.6e-37	31.3
WP_080624034.1\|4019245_4019905_-	LysM peptidoglycan-binding domain-containing protein	A0A090DBR9	Clostridium_phage	3.7e-25	32.8
WP_080624035.1\|4019897_4025162_-	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	5.0e-48	40.9
WP_096748223.1\|4025165_4025315_-	hypothetical protein	NA	NA	NA	NA
WP_080624036.1\|4025344_4025794_-\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	5.0e-10	31.9
WP_080624038.1\|4026508_4026592_+	hydrophobic toxin	NA	NA	NA	NA
WP_080624039.1\|4026864_4027308_-\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	1.2e-27	46.6
WP_080624040.1\|4027309_4028710_-\|tail	phage tail sheath protein	A0A0A7RTT5	Clostridium_phage	1.1e-84	42.0
WP_080624041.1\|4028710_4028938_-	hypothetical protein	NA	NA	NA	NA
WP_080624042.1\|4028938_4029403_-\|portal	phage portal protein	NA	NA	NA	NA
WP_080624043.1\|4029392_4029890_-	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	1.5e-39	46.5
WP_080624044.1\|4029886_4030243_-	YqbH/XkdH family protein	NA	NA	NA	NA
WP_080624045.1\|4030239_4030635_-	DUF3199 family protein	A0A1B1P7D6	Bacillus_phage	6.4e-17	39.5
WP_080624046.1\|4030641_4031055_-	hypothetical protein	NA	NA	NA	NA
WP_080624047.1\|4031065_4032001_-\|capsid	major capsid protein	A0A1B1P7E3	Bacillus_phage	7.8e-106	64.4
WP_080624048.1\|4032013_4033189_-\|terminase	terminase	A0A1B1P7E4	Bacillus_phage	1.9e-80	51.0
WP_080624049.1\|4033194_4034067_-	hypothetical protein	NA	NA	NA	NA
WP_080624050.1\|4034115_4035033_-	hypothetical protein	A0A1B1P7D7	Bacillus_phage	1.1e-51	38.9
WP_080624051.1\|4035025_4036564_-\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	7.7e-143	50.7
WP_080624052.1\|4036567_4037863_-\|terminase	PBSX family phage terminase large subunit	M4ZRM5	Bacillus_phage	2.6e-160	63.9
WP_080624053.1\|4037859_4038729_-\|terminase	terminase	D2IYW0	Enterococcus_phage	1.3e-38	43.3
WP_080624054.1\|4038915_4039206_-	hypothetical protein	NA	NA	NA	NA
WP_080624055.1\|4039496_4039700_-	hypothetical protein	NA	NA	NA	NA
WP_157765913.1\|4039753_4039927_-	hypothetical protein	NA	NA	NA	NA
WP_080624230.1\|4040203_4040665_-	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_080624056.1\|4040688_4042566_-\|integrase	integrase	A0A1P8CWI7	Bacillus_phage	6.8e-16	23.6
WP_096748224.1\|4042847_4043951_+	tetratricopeptide repeat protein	A0A1P8CWN8	Bacillus_phage	3.7e-46	31.1
4042813:4042827	attR	NA	NA	NA	NA
WP_080624058.1\|4044131_4044515_-	ArpU family transcriptional regulator	Q9ZXB9	Bacillus_phage	9.8e-31	57.9
WP_080624059.1\|4044605_4045259_-	hypothetical protein	NA	NA	NA	NA
WP_080624060.1\|4045255_4045456_-	hypothetical protein	A0A1L2JY31	Aeribacillus_phage	2.8e-13	63.6
WP_080624061.1\|4045474_4045708_-	hypothetical protein	NA	NA	NA	NA
WP_080624062.1\|4045782_4046340_+	GNAT family N-acetyltransferase	O64026	Bacillus_phage	3.1e-49	53.4
WP_149208611.1\|4046332_4046545_-	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	5.1e-13	61.4
WP_080624063.1\|4046612_4046879_-	DUF3850 domain-containing protein	A8E2L6	Enterococcus_phage	1.0e-18	59.2
WP_167511159.1\|4047121_4047799_-	hypothetical protein	NA	NA	NA	NA
WP_080624064.1\|4047768_4048227_-	RusA family crossover junction endodeoxyribonuclease	S6B1L9	Thermus_phage	2.2e-53	69.8
WP_080624065.1\|4048363_4048624_-	IDEAL domain-containing protein	NA	NA	NA	NA
WP_080624233.1\|4048731_4048908_-	Fur-regulated basic protein FbpA	M4ZS77	Bacillus_phage	1.0e-06	50.9
WP_080624066.1\|4048943_4050248_-	replicative DNA helicase	D2XR44	Bacillus_phage	9.0e-92	42.5
WP_080624067.1\|4050222_4050504_-	hypothetical protein	NA	NA	NA	NA
WP_080624068.1\|4050506_4051319_-	hypothetical protein	S6BFM4	Thermus_phage	3.7e-11	50.0
WP_080624069.1\|4051486_4052437_-	recombination protein RecT	S6AVW6	Thermus_phage	1.2e-88	60.8
WP_080624070.1\|4052429_4053380_-	hypothetical protein	S6C475	Thermus_phage	2.3e-105	61.7
WP_017474946.1\|4053379_4053559_-	hypothetical protein	NA	NA	NA	NA
WP_080624071.1\|4053679_4053892_-	hypothetical protein	NA	NA	NA	NA
WP_080624072.1\|4053904_4054099_-	hypothetical protein	NA	NA	NA	NA
WP_080624073.1\|4054226_4054415_-	hypothetical protein	NA	NA	NA	NA
WP_080624074.1\|4054415_4054682_-	hypothetical protein	NA	NA	NA	NA
WP_080624075.1\|4054678_4055206_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_080624077.1\|4055504_4055708_-	helix-turn-helix transcriptional regulator	B5LPU7	Bacillus_virus	1.1e-09	50.8
WP_080624234.1\|4055906_4056254_+	helix-turn-helix transcriptional regulator	D2XQ11	Bacillus_virus	3.1e-15	50.0

DBSCAN-SWA_8

4327008 : 4383953

Bacillus_phage(36.36%)

tRNA,transposase,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020452419.1\|4327008_4328154_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.1e-84	43.2
WP_020452420.1\|4328182_4329211_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_003183984.1\|4329251_4329452_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_023855398.1\|4329444_4330449_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	1.2e-06	30.3
WP_023855399.1\|4330458_4331064_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_023855400.1\|4331187_4331709_-	intercompartmental signaling factor BofC	NA	NA	NA	NA
WP_035338454.1\|4331940_4332588_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_035338455.1\|4333067_4333259_-	hypothetical protein	NA	NA	NA	NA
WP_035338155.1\|4333787_4335218_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-121	48.8
WP_035338349.1\|4335250_4336588_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_035338348.1\|4336584_4337256_-	response regulator transcription factor	W8CYM9	Bacillus_phage	6.3e-25	32.0
WP_023855402.1\|4337434_4337614_-	small acid-soluble spore protein H	NA	NA	NA	NA
WP_023855403.1\|4337722_4338187_-	DNA damage-inducible protein DinB	NA	NA	NA	NA
WP_023855404.1\|4338246_4338957_-	poly-gamma-glutamate hydrolase family protein	F8WQ53	Bacillus_phage	1.9e-48	54.9
WP_003183993.1\|4339351_4339531_+	hypothetical protein	A0A1P8CWV7	Bacillus_phage	1.5e-21	76.3
WP_035338347.1\|4339620_4339941_-	hypothetical protein	NA	NA	NA	NA
WP_023855406.1\|4340078_4340801_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_023855407.1\|4340925_4341561_-	spore cortex protein	NA	NA	NA	NA
WP_023855408.1\|4341733_4342786_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_035338345.1\|4342901_4344011_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_025811047.1\|4344032_4344872_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_025811046.1\|4344852_4346427_-	L-aspartate oxidase	NA	NA	NA	NA
WP_020452436.1\|4346527_4347706_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1X7QGF3	Faustovirus	1.1e-32	26.0
WP_020452437.1\|4347674_4348217_+	transcription repressor NadR	NA	NA	NA	NA
WP_020452438.1\|4348258_4349128_-	prephenate dehydratase	NA	NA	NA	NA
WP_023855415.1\|4349137_4349581_-	ACT domain-containing protein	NA	NA	NA	NA
WP_020452440.1\|4349698_4350985_-	GTPase ObgE	NA	NA	NA	NA
WP_020452441.1\|4351017_4351596_-	sporulation initiation phosphotransferase Spo0B	NA	NA	NA	NA
WP_003184023.1\|4351822_4352104_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_020452442.1\|4352116_4352458_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003184027.1\|4352470_4352779_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_096748261.1\|4352939_4353806_-	stage IV sporulation protein FB	NA	NA	NA	NA
WP_023855419.1\|4353798_4354590_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_025811043.1\|4354735_4355164_+	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_023855421.1\|4355163_4355487_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_020452447.1\|4355533_4356340_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_096748468.1\|4356342_4357023_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_020452449.1\|4357076_4357595_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_020452450.1\|4357591_4358500_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_003184042.1\|4358530_4359541_-	rod shape-determining protein	NA	NA	NA	NA
WP_020452451.1\|4359628_4360303_-	JAB domain-containing protein	NA	NA	NA	NA
WP_020452452.1\|4360357_4360930_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_096748262.1\|4361080_4362115_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_023855425.1\|4362320_4363070_-	prepilin peptidase	NA	NA	NA	NA
WP_096748263.1\|4363222_4364527_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_020452456.1\|4364603_4367246_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	9.8e-162	42.3
WP_020452457.1\|4367705_4367897_+	hypothetical protein	NA	NA	NA	NA
WP_096748264.1\|4367915_4368938_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_096748265.1\|4368965_4370597_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_023855430.1\|4370745_4372041_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_020452461.1\|4372066_4373041_-	porphobilinogen synthase	NA	NA	NA	NA
WP_026579130.1\|4373044_4373836_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_020452463.1\|4373825_4374767_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_020452464.1\|4374806_4375637_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_020452465.1\|4375642_4377004_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_020452466.1\|4377192_4377678_+	hypothetical protein	NA	NA	NA	NA
WP_075752023.1\|4377725_4378313_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_023855433.1\|4378309_4380634_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.7e-186	45.0
WP_096748266.1\|4380850_4382506_-\|protease	ATP-dependent protease LonB	A0A0R6PGP8	Moraxella_phage	1.4e-17	34.7
WP_003184083.1\|4382687_4383953_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	7.2e-147	63.5

Anti-CRISPR protein detection

Acr_ID: NZ_CP043501.1|WP_003183993.1|4339351_4339531_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP043501.1|WP_003183993.1|4339351_4339531_+|hypothetical-protein

4339351_4339531_+

59 aa aa

4327008-4383953

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location
NZ_CP043501_3	Orphan	3.4\|4369639\|21\|NZ_CP043501\|CRT	4369639-4369659	21	4369807-4369827
NZ_CP043501_3	Orphan	3.5\|4369681\|21\|NZ_CP043501\|CRT	4369681-4369701	21	4369807-4369827
NZ_CP043501_3	Orphan	3.6\|4369723\|21\|NZ_CP043501\|CRT	4369723-4369743	21	4369807-4369827
NZ_CP043501_3	Orphan	3.7\|4369765\|21\|NZ_CP043501\|CRT	4369765-4369785	21	4369807-4369827

1. spacer 3.4|4369639|21|NZ_CP043501|CRT matches to NZ_CP043501 position: 4369807-4369827, mismatch: 0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

2. spacer 3.5|4369681|21|NZ_CP043501|CRT matches to NZ_CP043501 position: 4369807-4369827, mismatch: 0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

3. spacer 3.6|4369723|21|NZ_CP043501|CRT matches to NZ_CP043501 position: 4369807-4369827, mismatch: 0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

4. spacer 3.7|4369765|21|NZ_CP043501|CRT matches to NZ_CP043501 position: 4369807-4369827, mismatch: 0

actttctcccttttcagctca	CRISPR spacer
actttctcccttttcagctca	Protospacer
*********************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP043501

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information