CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP043944	Escherichia coli strain AR216.2b plasmid pMPNDM-5, complete sequence	0 crisprs	NA	0	2
NZ_CP043942	Escherichia coli strain AR216.2b chromosome, complete genome	9 crisprs	csa3,PD-DExK,RT,WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4	15	7
NZ_CP043945	Escherichia coli strain AR216.2b plasmid pMPCMY-2, complete sequence	0 crisprs	NA	0	0
NZ_CP043943	Escherichia coli strain AR216.2b plasmid pMPTEM-30, complete sequence	0 crisprs	DEDDh,RT,c2c9_V-U4	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1262 : 47322

Escherichia_phage(46.15%)

transposase,protease,integrase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001066953.1\|1262_2003_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	2.0e-24	57.6
WP_001309252.1\|2123_2312_-	hypothetical protein	NA	NA	NA	NA
WP_001072358.1\|2678_3848_+	hypothetical protein	NA	NA	NA	NA
WP_001322642.1\|4694_4967_-	transcriptional regulator	NA	NA	NA	NA
WP_001496335.1\|6209_8180_+	TonB-dependent hemoglobin/transferrin/lactoferrin family receptor	NA	NA	NA	NA
WP_000977394.1\|8186_8978_+	DUF4198 domain-containing protein	NA	NA	NA	NA
WP_001317493.1\|9716_10499_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	5.9e-139	99.6
WP_000255956.1\|10495_11518_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
WP_024193849.1\|12597_12972_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.8e-60	100.0
WP_001067855.1\|12996_13701_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000219391.1\|13822_14728_+	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_000004159.1\|14724_15963_+	MFS transporter	NA	NA	NA	NA
WP_001137892.1\|15962_16547_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001336397.1\|16492_16849_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|17776_18481_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000557452.1\|18587_19448_+	aminoglycoside N-acetyltransferase AAC(3)-IIa	NA	NA	NA	NA
WP_002063889.1\|19460_20003_+	AAA family ATPase	NA	NA	NA	NA
WP_001067855.1\|21196_21901_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_023408309.1\|22459_23272_+	subclass B1 metallo-beta-lactamase NDM-5	NA	NA	NA	NA
WP_004201167.1\|23275_23641_+	bleomycin binding protein Ble-MBL	NA	NA	NA	NA
WP_004201168.1\|23645_24284_+	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
WP_004201169.1\|24294_25326_-	twin-arginine translocation (TAT) pathway signal sequence domain protein	NA	NA	NA	NA
WP_000050481.1\|25638_27180_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000259031.1\|27584_28424_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|28417_28765_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001206356.1\|28928_29720_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_001336345.1\|29725_30016_-	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_001083725.1\|30127_30625_-	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_060591625.1\|30769_31657_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	9.2e-56	42.2
WP_001067855.1\|31690_32395_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_032140899.1\|34016_34259_+	hypothetical protein	NA	NA	NA	NA
WP_000470728.1\|34290_34968_-	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_000804064.1\|35046_36246_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_000058717.1\|36277_37162_-	EamA family transporter	NA	NA	NA	NA
WP_001351729.1\|37299_37692_-	cysteine hydrolase	NA	NA	NA	NA
WP_000509965.1\|38468_39074_-	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	9.4e-20	35.3
WP_001553819.1\|39168_42066_+\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	4.2e-182	37.8
WP_001398199.1\|42202_42604_-	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_000557619.1\|42536_42794_-	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_000616807.1\|42886_43540_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_012311408.1\|43729_44116_-	hypothetical protein	NA	NA	NA	NA
WP_032152935.1\|44478_45336_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_001365705.1\|45328_45403_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_072163418.1\|45486_45597_+	replication protein RepA	NA	NA	NA	NA
WP_000083821.1\|45637_45895_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_071529016.1\|45861_46113_+	hypothetical protein	NA	NA	NA	NA
WP_000156883.1\|46299_47322_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

60477 : 68857

Stx2-converting_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023149734.1\|60477_62049_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.9e-169	58.5
WP_000624622.1\|62068_62416_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|62415_63093_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_077779935.1\|63069_63237_+	hypothetical protein	U5P0U6	Shigella_phage	7.8e-09	100.0
WP_001496308.1\|63230_63353_-	hypothetical protein	NA	NA	NA	NA
WP_005012601.1\|63537_63750_-	hypothetical protein	NA	NA	NA	NA
WP_000139363.1\|63883_64444_-	fertility inhibition protein FinO	NA	NA	NA	NA
WP_086625070.1\|64498_65275_-	type-F conjugative transfer system pilin acetylase TraX	A0A077JBM8	Xanthomonas_phage	3.3e-09	30.5
WP_000271685.1\|65380_65803_-	DUF1380 family protein	NA	NA	NA	NA
WP_001666994.1\|65849_66152_-	antirestriction protein	NA	NA	NA	NA
WP_001006251.1\|66688_67459_-	hypothetical protein	NA	NA	NA	NA
WP_001546462.1\|67503_67938_-	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_001104873.1\|67951_68173_-	hypothetical protein	NA	NA	NA	NA
WP_032181561.1\|68173_68857_-	DNA methylase	A0A2I7RE86	Vibrio_phage	1.1e-29	36.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP043942

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043942_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_1

1084312-1084646

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACC	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACC	CRT

5 spacers

The CRISPR arrays of NZ_CP043942_1

>merge|NZ_CP043942|1|1084312-1084646|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCTGTGTTTGCGGCATTAACGCTCACCAGTATTTCGTGTTCCCCGCGCCAGCGGGGATAAACCGACGTGGTCATGGGTGCTGCTGTTGCAGAGCCAGTGTTCCCCGCGCCAGCGGGGATAAACCGAGCAGATACACGGCTTTGTATTCCGTGCGCCCGTGTTCCCCGCGCCAGCGGGGATAAACCGAATAGCAATAGTCCATAGATTTGCGAAAACAGGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACCAC

>NZ_CP043942|1|1|1084312-1084644|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGTATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GACGTGGTCATGGGTGCTGCTGTTGCAGAGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

>NZ_CP043942|1|1|1084312-1084646|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCTG	TGTTTGCGGCATTAACGCTCACCAGTATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	CGTGGTCATGGGTGCTGCTGTTGCAGAGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	GCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACCGA	ATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACCGG	AGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCAC

>NZ_CP043942|1|1|1084312-1084644|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGTATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GACGTGGTCATGGGTGCTGCTGTTGCAGAGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAGCAGATACACGGCTTTGTATTCCGTGCGCCC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_001288228.1\|1083021_1083162_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_000581937.1\|1077379_1077628_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP043942.1\|WP_039023141.1\|1085283_1086762_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP043942.1\|WP_001130266.1\|1093886_1094462_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP043942.1\|WP_000021334.1\|1088384_1089170_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP043942.1\|WP_000059306.1\|1089239_1090694_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP043942.1\|WP_001299652.1\|1092102_1092882_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP043942.1\|WP_000046812.1\|1073718_1075020_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP043942.1\|WP_001268460.1\|1082135_1083008_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP043942.1\|WP_001199973.1\|1083300_1083972_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP043942.1\|WP_001098105.1\|1090787_1092125_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP043942.1\|WP_001164544.1\|1086788_1088066_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP043942.1\|WP_000226815.1\|1075067_1077302_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP043942.1\|WP_000109529.1\|1094478_1094739_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP043942.1\|WP_001301334.1\|1094729_1096001_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP043942.1\|WP_000254738.1\|1077627_1077963_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP043942.1\|WP_001299097.1\|1092878_1093739_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP043942.1\|WP_000036723.1\|1080777_1082076_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP043942.1\|WP_000210878.1\|1079052_1080690_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP043942.1\|WP_001071648.1\|1078033_1078825_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_000581937.1\|1077379_1077628_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP043942.1\|WP_000021334.1\|1088384_1089170_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.96451e-139
NZ_CP043942.1\|WP_039023141.1\|1085283_1086762_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	4.82999e-110
NZ_CP043942.1\|WP_001130266.1\|1093886_1094462_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP043942.1\|WP_001299652.1\|1092102_1092882_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
NZ_CP043942.1\|WP_000059306.1\|1089239_1090694_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.41244e-83
NZ_CP043942.1\|WP_000046812.1\|1073718_1075020_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP043942.1\|WP_001268460.1\|1082135_1083008_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.25867e-100
NZ_CP043942.1\|WP_001199973.1\|1083300_1083972_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP043942.1\|WP_001098105.1\|1090787_1092125_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
NZ_CP043942.1\|WP_000226815.1\|1075067_1077302_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP043942.1\|WP_000109529.1\|1094478_1094739_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	7.43419e-42
NZ_CP043942.1\|WP_001301334.1\|1094729_1096001_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	5.03655e-125
NZ_CP043942.1\|WP_000036723.1\|1080777_1082076_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP043942.1\|WP_001164544.1\|1086788_1088066_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.60446e-29
NZ_CP043942.1\|WP_001299097.1\|1092878_1093739_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	7.42017e-90
NZ_CP043942.1\|WP_000254738.1\|1077627_1077963_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP043942.1\|WP_000210878.1\|1079052_1080690_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP043942.1\|WP_001071648.1\|1078033_1078825_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160

>NZ_CP043942.1|WP_001199973.1|1083300_1083972_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP043942.1|WP_001288228.1|1083021_1083162_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNEYKITDAAVNLFIQI
>NZ_CP043942.1|WP_001268460.1|1082135_1083008_-|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIVVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVCISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASGRW
>NZ_CP043942.1|WP_000036723.1|1080777_1082076_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP043942.1|WP_000210878.1|1079052_1080690_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP043942.1|WP_001071648.1|1078033_1078825_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP043942.1|WP_000254738.1|1077627_1077963_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP043942.1|WP_000581937.1|1077379_1077628_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP043942.1|WP_000226815.1|1075067_1077302_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP043942.1|WP_000046812.1|1073718_1075020_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP043942.1|WP_039023141.1|1085283_1086762_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEVLGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDNMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP043942.1|WP_001164544.1|1086788_1088066_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLTLTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALGMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP043942.1|WP_000021334.1|1088384_1089170_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP043942.1|WP_000059306.1|1089239_1090694_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKVTGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNIVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP043942.1|WP_001098105.1|1090787_1092125_+|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP043942.1|WP_001299652.1|1092102_1092882_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP043942.1|WP_001299097.1|1092878_1093739_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP043942.1|WP_001130266.1|1093886_1094462_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP043942.1|WP_000109529.1|1094478_1094739_-|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTAERLINACPAGLFSLTPEGNLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP043942.1|WP_001301334.1|1094729_1096001_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGVTTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NZ_CP043942_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_2

1110195-1110896

TypeI-E

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

11 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP043942_2

>merge|NZ_CP043942|2|1110195-1110896|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCGTTTGGATCGGGTCTGGAATTTCTGAGCGGTCGCGAGTTCCCCGCGCCAGCGGGGATAAACCGCGAATCGCGCATACCCTGCGCGTCGCCGCCTGCGAGTTCCCCGCGCCAGCGGGGATAAACCGTCAGCTTTATAAATCCGGAGATACGGAAACTAGAGTTCCCCGCGCCAGCGGGGATAAACCGGACTCACCCCGAAAGAGATTGCCAGCCAGCTTGAGTTCCCCGCGCCAGCGGGGATAAACCGCTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCAGAGTTCCCCGCGCCAGCGGGGATAAACCGCCCACCAGCGCGTTTTTTGCCGGGGCCATAGTGAGTTCCCCGCGCCAGCGGGGATAAACCGTTGAACTCACCACGATTGTTAATATGGACGATGAGTTCCCCGCGCCAGCGGGGATAAACCGGGGGGCGCATGACCGTAAACATTATCCCCCGGGAGTTCCCCGCGCCAGCGGGGATAAACCGGGAGTTCAGACATAGGTGGAATGATGGACTACGAGTTCCCCGCGTTAGCGGGGATAAACCGCCCGGTAGCCAGGTTTGCAACGCCTGAACCGAGAGTTCCCCGCGCCAGCAGGGATAAACCGGCAACGACGGTGAGATTTCACGCCTGACGCTGGTGTTCCCCGCATCAGCGGGGATAAACCG

>NZ_CP043942|2|2|1110195-1110652|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGGATCGGGTCTGGAATTTCTGAGCGGTCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCGCGCATACCCTGCGCGTCGCCGCCTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAGCTTTATAAATCCGGAGATACGGAAACTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCACCCCGAAAGAGATTGCCAGCCAGCTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCACCAGCGCGTTTTTTGCCGGGGCCATAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTGAACTCACCACGATTGTTAATATGGACGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP043942|2|2|1110195-1110896|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGGATCGGGTCTGGAATTTCTGAGCGGTCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCGCGCATACCCTGCGCGTCGCCGCCTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAGCTTTATAAATCCGGAGATACGGAAACTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCACCCCGAAAGAGATTGCCAGCCAGCTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCACCAGCGCGTTTTTTGCCGGGGCCATAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTGAACTCACCACGATTGTTAATATGGACGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGGCGCATGACCGTAAACATTATCCCCCGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGTTCAGACATAGGTGGAATGATGGACTAC
GAGTTCCCCGCGTTAGCGGGGATAAACCG	CCCGGTAGCCAGGTTTGCAACGCCTGAACCGA
GAGTTCCCCGCGCCAGCAGGGATAAACCG	GCAACGACGGTGAGATTTCACGCCTGACGCTG
GTGTTCCCCGCATCAGCGGGGATAAACCG

>NZ_CP043942|2|2|1110195-1110896|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTGGATCGGGTCTGGAATTTCTGAGCGGTCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGAATCGCGCATACCCTGCGCGTCGCCGCCTGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAGCTTTATAAATCCGGAGATACGGAAACTA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACTCACCCCGAAAGAGATTGCCAGCCAGCTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCTGGAGCTGGCTGCAAGGCAAGCCGCCCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCACCAGCGCGTTTTTTGCCGGGGCCATAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTGAACTCACCACGATTGTTAATATGGACGAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGGCGCATGACCGTAAACATTATCCCCCGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGAGTTCAGACATAGGTGGAATGATGGACTAC
GAGTTCCCCGCGTTAGCGGGGATAAACCG	CCCGGTAGCCAGGTTTGCAACGCCTGAACCGA
GAGTTCCCCGCGCCAGCAGGGATAAACCG	GCAACGACGGTGAGATTTCACGCCTGACGCTG
GTGTTCCCCGCATCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_000064450.1\|1106515_1107607_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP043942.1\|WP_000752800.1\|1106020_1106503_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|187801
NZ_CP043942.1\|WP_000220066.1\|1108885_1109803_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP043942.1\|WP_071532149.1\|1104543_1106028_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|236613
NZ_CP043942.1\|WP_000490428.1\|1110978_1112016_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP043942.1\|WP_000372108.1\|1112267_1113176_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP043942.1\|WP_000517476.1\|1115776_1116088_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP043942.1\|WP_001090361.1\|1113177_1114605_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP043942.1\|WP_001334996.1\|1107609_1108284_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_CP043942.1\|WP_000246138.1\|1116106_1116817_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP043942.1\|WP_001246104.1\|1115259_1115583_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP043942.1\|WP_000039850.1\|1100345_1101080_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP043942.1\|WP_001381369.1\|1109804_1110089_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP043942.1\|WP_001290679.1\|1098558_1100271_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP043942.1\|WP_000433154.1\|1101438_1104105_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP043942.1\|WP_000568943.1\|1117292_1118342_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP043942.1\|WP_001219242.1\|1116816_1117296_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP043942.1\|WP_001295182.1\|1118322_1119084_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP043942.1\|WP_000281400.1\|1108270_1108870_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP043942.1\|WP_001173673.1\|1114604_1115210_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_000064450.1\|1106515_1107607_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	5.43824e-154
NZ_CP043942.1\|WP_000752800.1\|1106020_1106503_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187801	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.76293e-33
NZ_CP043942.1\|WP_000220066.1\|1108885_1109803_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.68794e-159
NZ_CP043942.1\|WP_071532149.1\|1104543_1106028_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|236613	PRK09693, PRK09693, Cascade antiviral complex protein; Validated.	0
NZ_CP043942.1\|WP_000490428.1\|1110978_1112016_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP043942.1\|WP_000372108.1\|1112267_1113176_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP043942.1\|WP_000517476.1\|1115776_1116088_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP043942.1\|WP_001090361.1\|1113177_1114605_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP043942.1\|WP_001334996.1\|1107609_1108284_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	2.15381e-103
NZ_CP043942.1\|WP_000246138.1\|1116106_1116817_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP043942.1\|WP_001246104.1\|1115259_1115583_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP043942.1\|WP_000039850.1\|1100345_1101080_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	2.39575e-137
NZ_CP043942.1\|WP_001381369.1\|1109804_1110089_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	4.76227e-62
NZ_CP043942.1\|WP_001290679.1\|1098558_1100271_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP043942.1\|WP_000433154.1\|1101438_1104105_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	0
NZ_CP043942.1\|WP_000568943.1\|1117292_1118342_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP043942.1\|WP_001219242.1\|1116816_1117296_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP043942.1\|WP_001295182.1\|1118322_1119084_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP043942.1\|WP_000281400.1\|1108270_1108870_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.81669e-101
NZ_CP043942.1\|WP_001173673.1\|1114604_1115210_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148

>NZ_CP043942.1|WP_001381369.1|1109804_1110089_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMLVVVTENVPPRLRGRLAIWLLEVRAGVYVGDVSAKIREMIWEQIAGLAEEGNVVMAWATNTETGFEFQTFGLNRRTPVDLDGLRLVSFLPV
>NZ_CP043942.1|WP_000220066.1|1108885_1109803_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS
>NZ_CP043942.1|WP_000281400.1|1108270_1108870_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQTVCFEGVLTINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
>NZ_CP043942.1|WP_001334996.1|1107609_1108284_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGGDIYSEESVTGHHLKFTARDEPMITLPRQFASREWYVIKGGMDVSQ
>NZ_CP043942.1|WP_000064450.1|1106515_1107607_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLKSWVRNNGEA
>NZ_CP043942.1|WP_000752800.1|1106020_1106503_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MADEIDAMALYRAWQQLDNGSCAQIRRVSEPDELRDIPAFYRLVQPFGWENPRHQQALLRMVFCLSAGKNVIRHQDKKSEQTTGISLGRALANSGRINERRIFQLIRADRTADMVQLRRLLTHAEPVLDWPLMARMLTWWGKRERQQLLEDFVLTTNKNA
>NZ_CP043942.1|WP_071532149.1|1104543_1106028_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPVTTFVRGIDLRSTVLLNVLTLPRLQKQFPNESHTENQPTWIKPIKSNESIPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG
>NZ_CP043942.1|WP_000433154.1|1101438_1104105_+|CRISPR-associated-helicase/endonuclease-Cas3
MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWDQSVVLQNTFCRNEMLSKQRVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLNGPSTQMCRKFNHGAAGLYWFNQDSLSEQSLGDFFSFFDAAPHPYESWFPWVEAVTGHHGFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCSSLLAGFCSLADWLGSWTTTNTFLFNEDAPSDINALRTYFQDRQQDASRVLELSGLVSNKRCYEGVHALLDNGYQPRQLQVLVDALPVAPGLTVIEAPTGSGKTETALAYAWKLIDQQIADSVIFALPTQATANAMLTRMEASASHLFSSPNLILAHGNSRFNHLFQSIKSRAITEQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLIVDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPVENNSAYPLINWRGVNGAQRFDLLAHPEQLPPRFSIQPEPIYLADMLPDLTMLERMIAAANAGAQACLICNLVDVAQVCYQRLKELNNTQVDIDLFHARFTLNDRREKENRVISNFGKNGKRNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEIPVATILLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEMDEPEWVGNGMDKFESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLPYVQTSSGKQLLDGQVYEDLSHEQQYEALALNRVNVPFTWKRSFSEVVDEDGLLWLEGKQNLDGWVWQGNSIVITYTGDEGMTRVIPANPK
>NZ_CP043942.1|WP_000039850.1|1100345_1101080_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP043942.1|WP_001290679.1|1098558_1100271_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKHESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>NZ_CP043942.1|WP_000490428.1|1110978_1112016_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNHQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP043942.1|WP_000372108.1|1112267_1113176_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP043942.1|WP_001090361.1|1113177_1114605_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP043942.1|WP_001173673.1|1114604_1115210_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP043942.1|WP_001246104.1|1115259_1115583_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP043942.1|WP_000517476.1|1115776_1116088_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP043942.1|WP_000246138.1|1116106_1116817_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP043942.1|WP_001219242.1|1116816_1117296_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP043942.1|WP_000568943.1|1117292_1118342_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP043942.1|WP_001295182.1|1118322_1119084_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP043942_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_3

1606679-1606796

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_3

>merge|NZ_CP043942|3|1606679-1606796|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>NZ_CP043942|3|3|1606679-1606796|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_000948731.1\|1601591_1602950_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
NZ_CP043942.1\|WP_000140472.1\|1596162_1597062_-\|ISNCY-family-transposase	unknown	unknown	gnl\|CDD\|182167
NZ_CP043942.1\|WP_001000379.1\|1597254_1598445_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
NZ_CP043942.1\|WP_001220077.1\|1609796_1613549_+\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	unknown	unknown	gnl\|CDD\|182059
NZ_CP043942.1\|WP_001295211.1\|1619006_1619630_+\|DUF1175-domain-containing-protein	unknown	unknown	gnl\|CDD\|225774
NZ_CP043942.1\|WP_001225852.1\|1625822_1626599_+\|YfaP-family-protein	unknown	unknown	gnl\|CDD\|227021
NZ_CP043942.1\|WP_001209927.1\|1598441_1599701_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	unknown	unknown	gnl\|CDD\|225617
NZ_CP043942.1\|WP_000150333.1\|1595964_1596150_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182167
NZ_CP043942.1\|WP_001281225.1\|1614545_1617173_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502
NZ_CP043942.1\|WP_000990765.1\|1613676_1614399_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
NZ_CP043942.1\|WP_000135040.1\|1605197_1605452_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	unknown	unknown	gnl\|CDD\|182668
NZ_CP043942.1\|WP_001104551.1\|1624168_1625818_+\|DUF2300-domain-containing-protein	unknown	unknown	gnl\|CDD\|227732
NZ_CP043942.1\|WP_000857257.1\|1599690_1601319_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
NZ_CP043942.1\|WP_000332037.1\|1605451_1606582_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|181647
NZ_CP043942.1\|WP_000301050.1\|1604493_1605144_+\|lipopolysaccharide-kinase-InaA	unknown	unknown	gnl\|CDD\|182136
NZ_CP043942.1\|WP_125922847.1\|1619773_1624168_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP043942.1\|WP_000779105.1\|1602954_1604031_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
NZ_CP043942.1\|WP_000786547.1\|1626672_1627857_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NZ_CP043942.1\|WP_001075164.1\|1606815_1609101_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
NZ_CP043942.1\|WP_000012305.1\|1617321_1619010_+\|DUF2138-domain-containing-protein	unknown	unknown	gnl\|CDD\|227030

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_000948731.1\|1601591_1602950_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
NZ_CP043942.1\|WP_000140472.1\|1596162_1597062_-\|ISNCY-family-transposase	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	0
NZ_CP043942.1\|WP_001000379.1\|1597254_1598445_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
NZ_CP043942.1\|WP_001220077.1\|1609796_1613549_+\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
NZ_CP043942.1\|WP_001295211.1\|1619006_1619630_+\|DUF1175-domain-containing-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	7.99004e-141
NZ_CP043942.1\|WP_001225852.1\|1625822_1626599_+\|YfaP-family-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	4.17009e-153
NZ_CP043942.1\|WP_001209927.1\|1598441_1599701_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP043942.1\|WP_000150333.1\|1595964_1596150_-\|hypothetical-protein	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	1.35852e-30
NZ_CP043942.1\|WP_001281225.1\|1614545_1617173_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_CP043942.1\|WP_000990765.1\|1613676_1614399_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.65303e-171
NZ_CP043942.1\|WP_000135040.1\|1605197_1605452_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
NZ_CP043942.1\|WP_001104551.1\|1624168_1625818_+\|DUF2300-domain-containing-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	8.04949e-127
NZ_CP043942.1\|WP_000857257.1\|1599690_1601319_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
NZ_CP043942.1\|WP_000332037.1\|1605451_1606582_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
NZ_CP043942.1\|WP_000301050.1\|1604493_1605144_+\|lipopolysaccharide-kinase-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	2.86156e-158
NZ_CP043942.1\|WP_125922847.1\|1619773_1624168_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP043942.1\|WP_000779105.1\|1602954_1604031_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
NZ_CP043942.1\|WP_000786547.1\|1626672_1627857_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP043942.1\|WP_001075164.1\|1606815_1609101_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
NZ_CP043942.1\|WP_000012305.1\|1617321_1619010_+\|DUF2138-domain-containing-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0

>NZ_CP043942.1|WP_000332037.1|1605451_1606582_-|ribonucleotide-diphosphate-reductase-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>NZ_CP043942.1|WP_000135040.1|1605197_1605452_-|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>NZ_CP043942.1|WP_000301050.1|1604493_1605144_+|lipopolysaccharide-kinase-InaA
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>NZ_CP043942.1|WP_000779105.1|1602954_1604031_+|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDNLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMELNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTPDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>NZ_CP043942.1|WP_000948731.1|1601591_1602950_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQERNGG
>NZ_CP043942.1|WP_000857257.1|1599690_1601319_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>NZ_CP043942.1|WP_001209927.1|1598441_1599701_-|glycerol-3-phosphate-dehydrogenase-subunit-GlpB
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>NZ_CP043942.1|WP_001000379.1|1597254_1598445_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>NZ_CP043942.1|WP_000140472.1|1596162_1597062_-|ISNCY-family-transposase
MTESTASSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCH
>NZ_CP043942.1|WP_000150333.1|1595964_1596150_-|hypothetical-protein
MTIAERLRQEGHQIGWQEGKLEGLHEQAIKIALRMLEQGFDRDQVLAATQLSEADLAANNH
>NZ_CP043942.1|WP_001075164.1|1606815_1609101_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>NZ_CP043942.1|WP_001220077.1|1609796_1613549_+|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC
MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>NZ_CP043942.1|WP_000990765.1|1613676_1614399_-|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>NZ_CP043942.1|WP_001281225.1|1614545_1617173_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>NZ_CP043942.1|WP_000012305.1|1617321_1619010_+|DUF2138-domain-containing-protein
MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIAGDLLSGKKRWQASFGLEERTAEKTPVRQRIVVSARWLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGIAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>NZ_CP043942.1|WP_001295211.1|1619006_1619630_+|DUF1175-domain-containing-protein
MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>NZ_CP043942.1|WP_125922847.1|1619773_1624168_+|alpha-2-macroglobulin-family-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVKQFRYPLWQAKPFEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVIGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALAKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGENALILPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPALAGAWAKHKLTGGGEDWRWVGQGVPDILSFGDELSPQNVQVRWREPAKMAQQSNIPVTVERQLYRLIPGEEEMSFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>NZ_CP043942.1|WP_001104551.1|1624168_1625818_+|DUF2300-domain-containing-protein
MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGVTKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAVNPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTWARTMTAWTQDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKMPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>NZ_CP043942.1|WP_001225852.1|1625822_1626599_+|YfaP-family-protein
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPIHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>NZ_CP043942.1|WP_000786547.1|1626672_1627857_-|acetyl-CoA-C-acetyltransferase
MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN

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Crispr_ID: NZ_CP043942_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_4

2321063-2321186

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_4

>merge|NZ_CP043942|4|2321063-2321186|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP043942|4|4|2321063-2321186|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_001273527.1\|2313797_2315900_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP043942.1\|WP_001295403.1\|2310517_2311930_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699
NZ_CP043942.1\|WP_000098896.1\|2325066_2326215_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP043942.1\|WP_001070230.1\|2313150_2313777_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP043942.1\|WP_000269501.1\|2327829_2328762_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP043942.1\|WP_000493947.1\|2324385_2325027_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP043942.1\|WP_001310861.1\|2316614_2317283_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP043942.1\|WP_001174940.1\|2322797_2324171_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP043942.1\|WP_000534271.1\|2321500_2322757_+\|autotransporter-adhesin-related-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP043942.1\|WP_000528342.1\|2312486_2312696_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP043942.1\|WP_000190982.1\|2328758_2329784_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP043942.1\|WP_000701040.1\|2330337_2331507_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP043942.1\|WP_000007283.1\|2331741_2332323_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP043942.1\|WP_000587530.1\|2318068_2318881_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP043942.1\|WP_000517579.1\|2315903_2316551_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP043942.1\|WP_001069979.1\|2317279_2318065_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP043942.1\|WP_000716950.1\|2318892_2320497_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP043942.1\|WP_000102278.1\|2330082_2330172_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP043942.1\|WP_001182332.1\|2326505_2327717_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP043942.1\|WP_000212657.1\|2320622_2320928_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_001273527.1\|2313797_2315900_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP043942.1\|WP_001295403.1\|2310517_2311930_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP043942.1\|WP_000098896.1\|2325066_2326215_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP043942.1\|WP_001070230.1\|2313150_2313777_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP043942.1\|WP_000269501.1\|2327829_2328762_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP043942.1\|WP_000493947.1\|2324385_2325027_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP043942.1\|WP_001310861.1\|2316614_2317283_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
NZ_CP043942.1\|WP_001174940.1\|2322797_2324171_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP043942.1\|WP_000534271.1\|2321500_2322757_+\|autotransporter-adhesin-related-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP043942.1\|WP_000528342.1\|2312486_2312696_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP043942.1\|WP_000190982.1\|2328758_2329784_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP043942.1\|WP_000701040.1\|2330337_2331507_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NZ_CP043942.1\|WP_000007283.1\|2331741_2332323_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP043942.1\|WP_000587530.1\|2318068_2318881_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.58482e-174
NZ_CP043942.1\|WP_000517579.1\|2315903_2316551_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	3.717e-122
NZ_CP043942.1\|WP_001069979.1\|2317279_2318065_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.40835e-163
NZ_CP043942.1\|WP_000716950.1\|2318892_2320497_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP043942.1\|WP_001182332.1\|2326505_2327717_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP043942.1\|WP_000212657.1\|2320622_2320928_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64

>NZ_CP043942.1|WP_000212657.1|2320622_2320928_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP043942.1|WP_000716950.1|2318892_2320497_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEDSHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP043942.1|WP_000587530.1|2318068_2318881_+|hypothetical-protein
MIITQADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERPFCSQFARSDDHARIGCCEDNARITTAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>NZ_CP043942.1|WP_001069979.1|2317279_2318065_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQTHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP043942.1|WP_001310861.1|2316614_2317283_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP043942.1|WP_000517579.1|2315903_2316551_+|YdhW-family-putative-oxidoreductase-system-protein
MGKMNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYLVAEEELSVLLESIKQNGDYADIACLTGSKDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP043942.1|WP_001273527.1|2313797_2315900_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>NZ_CP043942.1|WP_001070230.1|2313150_2313777_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP043942.1|WP_000528342.1|2312486_2312696_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP043942.1|WP_001295403.1|2310517_2311930_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP043942.1|WP_000534271.1|2321500_2322757_+|autotransporter-adhesin-related-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINLNGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP043942.1|WP_001174940.1|2322797_2324171_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
>NZ_CP043942.1|WP_000493947.1|2324385_2325027_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP043942.1|WP_000098896.1|2325066_2326215_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP043942.1|WP_001182332.1|2326505_2327717_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKLVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>NZ_CP043942.1|WP_000269501.1|2327829_2328762_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP043942.1|WP_000190982.1|2328758_2329784_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP043942.1|WP_000102278.1|2330082_2330172_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP043942.1|WP_000701040.1|2330337_2331507_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP043942.1|WP_000007283.1|2331741_2332323_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP043942_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_5

2991338-2991429

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_5

>merge|NZ_CP043942|5|2991338-2991429|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP043942|5|5|2991338-2991429|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_001326840.1\|2980678_2984641_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP043942.1\|WP_001393558.1\|2986697_2987390_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP043942.1\|WP_001044279.1\|2992734_2993976_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP043942.1\|WP_000024560.1\|2996705_2997011_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP043942.1\|WP_001001176.1\|2988605_2989196_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP043942.1\|WP_001028083.1\|2989206_2989701_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP043942.1\|WP_000777653.1\|2987795_2988596_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP043942.1\|WP_000420621.1\|2995785_2996706_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP043942.1\|WP_001326838.1\|2989721_2991050_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP043942.1\|WP_000209894.1\|2997162_2997762_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP043942.1\|WP_001143120.1\|2992469_2992697_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP043942.1\|WP_001062091.1\|2997758_3000305_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP043942.1\|WP_001120125.1\|3001606_3002299_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711
NZ_CP043942.1\|WP_001340618.1\|2985606_2986698_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP043942.1\|WP_071524880.1\|2985497_2985677_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_000191701.1\|2984680_2985319_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP043942.1\|WP_001151437.1\|2991852_2992449_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP043942.1\|WP_001126780.1\|2987401_2987788_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP043942.1\|WP_000535367.1\|2994268_2995525_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP043942.1\|WP_001230242.1\|3000304_3001477_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_001326840.1\|2980678_2984641_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP043942.1\|WP_001393558.1\|2986697_2987390_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	1.22031e-169
NZ_CP043942.1\|WP_001044279.1\|2992734_2993976_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP043942.1\|WP_000024560.1\|2996705_2997011_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	5.75956e-65
NZ_CP043942.1\|WP_001001176.1\|2988605_2989196_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.68154e-128
NZ_CP043942.1\|WP_001028083.1\|2989206_2989701_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	1.5266e-105
NZ_CP043942.1\|WP_000777653.1\|2987795_2988596_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	3.53291e-142
NZ_CP043942.1\|WP_001143120.1\|2992469_2992697_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP043942.1\|WP_000209894.1\|2997162_2997762_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	1.00485e-84
NZ_CP043942.1\|WP_001326838.1\|2989721_2991050_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP043942.1\|WP_001062091.1\|2997758_3000305_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP043942.1\|WP_001120125.1\|3001606_3002299_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	1.16516e-137
NZ_CP043942.1\|WP_001340618.1\|2985606_2986698_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP043942.1\|WP_000420621.1\|2995785_2996706_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP043942.1\|WP_000191701.1\|2984680_2985319_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.3356e-153
NZ_CP043942.1\|WP_001151437.1\|2991852_2992449_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP043942.1\|WP_001126780.1\|2987401_2987788_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	5.99808e-85
NZ_CP043942.1\|WP_000535367.1\|2994268_2995525_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP043942.1\|WP_001230242.1\|3000304_3001477_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0

>NZ_CP043942.1|WP_001326838.1|2989721_2991050_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>NZ_CP043942.1|WP_001028083.1|2989206_2989701_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
>NZ_CP043942.1|WP_001001176.1|2988605_2989196_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
>NZ_CP043942.1|WP_000777653.1|2987795_2988596_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP043942.1|WP_001126780.1|2987401_2987788_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP043942.1|WP_001393558.1|2986697_2987390_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPKFAQKAALFNIETFFGWVSDVETFCDALSPTSFAHIA
>NZ_CP043942.1|WP_001340618.1|2985606_2986698_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP043942.1|WP_071524880.1|2985497_2985677_-|hypothetical-protein
MYCGAWVEMSQPLLPIGTNTPIFIINLSSSRKVKVRRGAASCISFSAAYWLVCKADASF
>NZ_CP043942.1|WP_000191701.1|2984680_2985319_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>NZ_CP043942.1|WP_001326840.1|2980678_2984641_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAKYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGTIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP043942.1|WP_001151437.1|2991852_2992449_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP043942.1|WP_001143120.1|2992469_2992697_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP043942.1|WP_001044279.1|2992734_2993976_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECPPPYTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDADGFCPMDKFDSVLNEAVK
>NZ_CP043942.1|WP_000535367.1|2994268_2995525_-|YccE-family-protein
MGSNIHGISCTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVCFMRLYNELRRKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRTLRTNDTQIYSGVSGGITYTIQYVRDIDIVRVSLPGRASESITDFKGYYWYNFMEYIENINACDDVFSEYCFDDENISVQPERINTPGISDLDSDIDLSGISFIQRETNQALGLKYAPVDGDGYCLLRAILVLKQHDYSWALVSYKMQKEVYNEFIKMVDKKTIEALVDTAFYNLREDVKTLFGVDLQSDNQIQGQSSLMSWSFLFFKKQFIDSCLNNEKCILHLPEFIFNDNKNLLALDTDTSDRIKAVKNFLAVLSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLNRYAI
>NZ_CP043942.1|WP_000420621.1|2995785_2996706_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP043942.1|WP_000024560.1|2996705_2997011_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
>NZ_CP043942.1|WP_000209894.1|2997162_2997762_-|molecular-chaperone-TorD
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLTAAVNELENRIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVARCRQYDSFGFYAALSQLLLVLVECDHQNR
>NZ_CP043942.1|WP_001062091.1|2997758_3000305_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP043942.1|WP_001230242.1|3000304_3001477_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP043942.1|WP_001120125.1|3001606_3002299_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQSVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP043942_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_6

3252834-3252978

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_6

>merge|NZ_CP043942|6|3252834-3252978|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NZ_CP043942|6|6|3252834-3252978|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_001295303.1\|3249508_3250798_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
NZ_CP043942.1\|WP_000042533.1\|3243218_3245240_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_CP043942.1\|WP_001340186.1\|3240732_3241722_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP043942.1\|WP_001295302.1\|3242118_3243027_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
NZ_CP043942.1\|WP_000604034.1\|3262214_3262904_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP043942.1\|WP_000044829.1\|3245818_3246496_-\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
NZ_CP043942.1\|WP_000891692.1\|3261153_3262212_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP043942.1\|WP_000246761.1\|3246488_3247244_-\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
NZ_CP043942.1\|WP_000118826.1\|3247230_3248385_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP043942.1\|WP_001036475.1\|3255445_3256879_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP043942.1\|WP_000891515.1\|3263843_3263993_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231
NZ_CP043942.1\|WP_000767389.1\|3250856_3251333_+\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
NZ_CP043942.1\|WP_000679972.1\|3258190_3259144_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP043942.1\|WP_001091569.1\|3251484_3252768_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP043942.1\|WP_000951213.1\|3248381_3249422_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|185063
NZ_CP043942.1\|WP_000593938.1\|3253001_3255263_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP043942.1\|WP_000723652.1\|3256954_3258007_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NZ_CP043942.1\|WP_000815435.1\|3259184_3260180_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP043942.1\|WP_001381038.1\|3260334_3261153_+\|pyridoxal-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP043942.1\|WP_000101983.1\|3262903_3263677_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_001295303.1\|3249508_3250798_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
NZ_CP043942.1\|WP_000042533.1\|3243218_3245240_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP043942.1\|WP_001340186.1\|3240732_3241722_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
NZ_CP043942.1\|WP_001295302.1\|3242118_3243027_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.22556e-139
NZ_CP043942.1\|WP_000604034.1\|3262214_3262904_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
NZ_CP043942.1\|WP_000044829.1\|3245818_3246496_-\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	1.13421e-109
NZ_CP043942.1\|WP_000891692.1\|3261153_3262212_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP043942.1\|WP_000246761.1\|3246488_3247244_-\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	7.9121e-172
NZ_CP043942.1\|WP_000118826.1\|3247230_3248385_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_CP043942.1\|WP_001036475.1\|3255445_3256879_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP043942.1\|WP_000891515.1\|3263843_3263993_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NZ_CP043942.1\|WP_000767389.1\|3250856_3251333_+\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.08182e-118
NZ_CP043942.1\|WP_000679972.1\|3258190_3259144_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
NZ_CP043942.1\|WP_001091569.1\|3251484_3252768_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP043942.1\|WP_000951213.1\|3248381_3249422_-\|biotin-synthase-BioB	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
NZ_CP043942.1\|WP_000593938.1\|3253001_3255263_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP043942.1\|WP_000723652.1\|3256954_3258007_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NZ_CP043942.1\|WP_000815435.1\|3259184_3260180_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP043942.1\|WP_001381038.1\|3260334_3261153_+\|pyridoxal-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP043942.1\|WP_000101983.1\|3262903_3263677_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0

>NZ_CP043942.1|WP_001091569.1|3251484_3252768_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP043942.1|WP_000767389.1|3250856_3251333_+|kinase-inhibitor
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>NZ_CP043942.1|WP_001295303.1|3249508_3250798_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>NZ_CP043942.1|WP_000951213.1|3248381_3249422_-|biotin-synthase-BioB
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>NZ_CP043942.1|WP_000118826.1|3247230_3248385_-|8-amino-7-oxononanoate-synthase
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>NZ_CP043942.1|WP_000246761.1|3246488_3247244_-|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
>NZ_CP043942.1|WP_000044829.1|3245818_3246496_-|ATP-dependent-dethiobiotin-synthetase-BioD
MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLHNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL
>NZ_CP043942.1|WP_000042533.1|3243218_3245240_-|excinuclease-ABC-subunit-B
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>NZ_CP043942.1|WP_001295302.1|3242118_3243027_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHNALEKALQALG
>NZ_CP043942.1|WP_001340186.1|3240732_3241722_-|GTP-3',8-cyclase-MoaA
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
>NZ_CP043942.1|WP_000593938.1|3253001_3255263_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVSRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP043942.1|WP_001036475.1|3255445_3256879_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP043942.1|WP_000723652.1|3256954_3258007_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP043942.1|WP_000679972.1|3258190_3259144_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NZ_CP043942.1|WP_000815435.1|3259184_3260180_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP043942.1|WP_001381038.1|3260334_3261153_+|pyridoxal-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDSFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP043942.1|WP_000891692.1|3261153_3262212_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>NZ_CP043942.1|WP_000604034.1|3262214_3262904_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP043942.1|WP_000101983.1|3262903_3263677_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQFKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASVQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGIKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK
>NZ_CP043942.1|WP_000891515.1|3263843_3263993_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP043942_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_7

3502959-3503055

Orphan

Consensus_repeat	Method
TTGTAGGCCTGATAAGATGCGTCAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_7

>merge|NZ_CP043942|7|3502959-3503055|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGCATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGGTTGTAGGCCTGATAAGACGCGTCAAGC

>NZ_CP043942|7|7|3502959-3503055|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGC	ATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGG
TTGTAGGCCTGATAAGACGCGTCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_000703900.1\|3508057_3509107_+\|ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|184985
NZ_CP043942.1\|WP_000855378.1\|3503088_3503982_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|181831
NZ_CP043942.1\|WP_000912385.1\|3498424_3499810_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NZ_CP043942.1\|WP_000255997.1\|3499983_3500478_+\|peptidylprolyl-isomerase-B	unknown	unknown	gnl\|CDD\|182734
NZ_CP043942.1\|WP_001143556.1\|3497867_3498389_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NZ_CP043942.1\|WP_000006900.1\|3513912_3515274_-\|allantoinase-AllB	unknown	unknown	gnl\|CDD\|169193
NZ_CP043942.1\|WP_000495367.1\|3504804_3506064_-\|DUF1116-domain-containing-protein	unknown	unknown	gnl\|CDD\|377673
NZ_CP043942.1\|WP_001295318.1\|3501320_3501830_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
NZ_CP043942.1\|WP_000729160.1\|3496679_3497546_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|236760
NZ_CP043942.1\|WP_000540997.1\|3510374_3511160_+\|(S)-ureidoglycine-aminohydrolase	unknown	unknown	gnl\|CDD\|200251
NZ_CP043942.1\|WP_000152519.1\|3503978_3504794_-\|DUF2877-domain-containing-protein	unknown	unknown	gnl\|CDD\|378658
NZ_CP043942.1\|WP_000988364.1\|3494754_3495447_-\|type-1-fimbria-chaperone-FimC	unknown	unknown	gnl\|CDD\|185117
NZ_CP043942.1\|WP_000212247.1\|3500480_3501203_+\|UDP-2,3-diacylglucosamine-diphosphatase	unknown	unknown	gnl\|CDD\|235420
NZ_CP043942.1\|WP_000815571.1\|3501826_3502894_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP043942.1\|WP_001302767.1\|3512554_3513856_-\|uracil/xanthine-transporter	unknown	unknown	gnl\|CDD\|183124
NZ_CP043942.1\|WP_000776555.1\|3495666_3496209_-\|type-1-fimbrial-protein-subunit-FimA	unknown	unknown	gnl\|CDD\|237920
NZ_CP043942.1\|WP_000580822.1\|3506073_3507741_-\|acyl-CoA-synthetase-FdrA	unknown	unknown	gnl\|CDD\|180395
NZ_CP043942.1\|WP_001333621.1\|3511387_3512533_-\|glycerate-3-kinase	unknown	unknown	gnl\|CDD\|182152
NZ_CP043942.1\|WP_000190288.1\|3497547_3497760_+\|ribosome-associated-protein-YbcJ	unknown	unknown	gnl\|CDD\|183166
NZ_CP043942.1\|WP_001310618.1\|3509128_3510364_+\|allantoate-deiminase	unknown	unknown	gnl\|CDD\|274471

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_000703900.1\|3508057_3509107_+\|ureidoglycolate-dehydrogenase	gnl\|CDD\|184985	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional.	0
NZ_CP043942.1\|WP_000855378.1\|3503088_3503982_-\|carbamate-kinase	gnl\|CDD\|181831	PRK09411, PRK09411, carbamate kinase; Reviewed.	0
NZ_CP043942.1\|WP_000912385.1\|3498424_3499810_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NZ_CP043942.1\|WP_000255997.1\|3499983_3500478_+\|peptidylprolyl-isomerase-B	gnl\|CDD\|182734	PRK10791, PRK10791, peptidylprolyl isomerase B.	9.12357e-121
NZ_CP043942.1\|WP_001143556.1\|3497867_3498389_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.2285e-30
NZ_CP043942.1\|WP_000006900.1\|3513912_3515274_-\|allantoinase-AllB	gnl\|CDD\|169193	PRK08044, PRK08044, allantoinase AllB.	0
NZ_CP043942.1\|WP_000495367.1\|3504804_3506064_-\|DUF1116-domain-containing-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.27269e-131
NZ_CP043942.1\|WP_001295318.1\|3501320_3501830_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	1.14024e-91
NZ_CP043942.1\|WP_000729160.1\|3496679_3497546_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NZ_CP043942.1\|WP_000540997.1\|3510374_3511160_+\|(S)-ureidoglycine-aminohydrolase	gnl\|CDD\|200251	TIGR03214, ura-cupin, putative allantoin catabolism protein. This model represents a protein containing a tandem arrangement of cupin domains (N-terminal part of pfam07883 and C-terminal more distantly related to pfam00190). This protein is found in the vicinity of genes involved in the catabolism of allantoin, a breakdown product of urate and sometimes of urate iteslf. The distribution of pathway components in the genomes in which this family is observed suggests that the function is linked to the allantoate catabolism to glyoxylate pathway (GenProp0686) since it is sometimes found in genomes lacking any elements of the xanthine-to-allantoin pathways (e.g. in Enterococcus faecalis).	2.39799e-151
NZ_CP043942.1\|WP_000152519.1\|3503978_3504794_-\|DUF2877-domain-containing-protein	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	3.47659e-37
NZ_CP043942.1\|WP_000988364.1\|3494754_3495447_-\|type-1-fimbria-chaperone-FimC	gnl\|CDD\|185117	PRK15195, PRK15195, molecular chaperone FimC.	4.4332e-149
NZ_CP043942.1\|WP_000212247.1\|3500480_3501203_+\|UDP-2,3-diacylglucosamine-diphosphatase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	2.41122e-165
NZ_CP043942.1\|WP_000815571.1\|3501826_3502894_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	2.50904e-178
NZ_CP043942.1\|WP_001302767.1\|3512554_3513856_-\|uracil/xanthine-transporter	gnl\|CDD\|183124	PRK11412, PRK11412, uracil/xanthine transporter.	0
NZ_CP043942.1\|WP_000776555.1\|3495666_3496209_-\|type-1-fimbrial-protein-subunit-FimA	gnl\|CDD\|237920	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA.	9.67411e-92
NZ_CP043942.1\|WP_000580822.1\|3506073_3507741_-\|acyl-CoA-synthetase-FdrA	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	0
NZ_CP043942.1\|WP_001333621.1\|3511387_3512533_-\|glycerate-3-kinase	gnl\|CDD\|182152	PRK09932, PRK09932, glycerate 3-kinase.	0
NZ_CP043942.1\|WP_000190288.1\|3497547_3497760_+\|ribosome-associated-protein-YbcJ	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	1.38756e-42
NZ_CP043942.1\|WP_001310618.1\|3509128_3510364_+\|allantoate-deiminase	gnl\|CDD\|274471	TIGR03176, AllC, allantoate amidohydrolase. This enzyme catalyzes the breakdown of allantoate, first to ureidoglycine by hydrolysis and then decarboxylation of one of the two equivalent ureido groups. Ureidoglycine then spontaneously exchanges ammonia for water resulting in ureidoglycolate. This enzyme is an alternative to allantoicase (3.5.3.4) which releases urea. [Central intermediary metabolism, Nitrogen metabolism].	0

>NZ_CP043942.1|WP_000815571.1|3501826_3502894_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAERSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEALIPLLPPEYASGVIWAQSKFG
>NZ_CP043942.1|WP_001295318.1|3501320_3501830_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGAA
>NZ_CP043942.1|WP_000212247.1|3500480_3501203_+|UDP-2,3-diacylglucosamine-diphosphatase
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>NZ_CP043942.1|WP_000255997.1|3499983_3500478_+|peptidylprolyl-isomerase-B
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTVSE
>NZ_CP043942.1|WP_000912385.1|3498424_3499810_-|cysteine--tRNA-ligase
MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
>NZ_CP043942.1|WP_001143556.1|3497867_3498389_+|metal-dependent-hydrolase
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFKFGVAYGNVFGHRGFTHSLVFVFVVPLLCVFIGRRWFRAGLIRCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLPGMLLMGMLWWRRR
>NZ_CP043942.1|WP_000190288.1|3497547_3497760_+|ribosome-associated-protein-YbcJ
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>NZ_CP043942.1|WP_000729160.1|3496679_3497546_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>NZ_CP043942.1|WP_000776555.1|3495666_3496209_-|type-1-fimbrial-protein-subunit-FimA
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
>NZ_CP043942.1|WP_000988364.1|3494754_3495447_-|type-1-fimbria-chaperone-FimC
MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSRSGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN
>NZ_CP043942.1|WP_000855378.1|3503088_3503982_-|carbamate-kinase
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
>NZ_CP043942.1|WP_000152519.1|3503978_3504794_-|DUF2877-domain-containing-protein
MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>NZ_CP043942.1|WP_000495367.1|3504804_3506064_-|DUF1116-domain-containing-protein
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPSWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
>NZ_CP043942.1|WP_000580822.1|3506073_3507741_-|acyl-CoA-synthetase-FdrA
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALMQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKTRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMIDPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>NZ_CP043942.1|WP_000703900.1|3508057_3509107_+|ureidoglycolate-dehydrogenase
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
>NZ_CP043942.1|WP_001310618.1|3509128_3510364_+|allantoate-deiminase
MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKELVATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLALMLYQLAWQK
>NZ_CP043942.1|WP_000540997.1|3510374_3511160_+|(S)-ureidoglycine-aminohydrolase
MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
>NZ_CP043942.1|WP_001333621.1|3511387_3512533_-|glycerate-3-kinase
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQALAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>NZ_CP043942.1|WP_001302767.1|3512554_3513856_-|uracil/xanthine-transporter
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
>NZ_CP043942.1|WP_000006900.1|3513912_3515274_-|allantoinase-AllB
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

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Crispr_ID: NZ_CP043942_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_8

3643097-3643241

Orphan

Consensus_repeat	Method
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_8

>merge|NZ_CP043942|8|3643097-3643241|CRISPRCasFinder
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCATCGGAGCACTTATTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGGTTCTGGCACCTTTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT

>NZ_CP043942|8|8|3643097-3643241|CRISPRCasFinder
TTTTGCAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT	CGGAGCACTTATTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGGTTCTGGCACC
TTTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_001310597.1\|3629984_3631802_-\|maltodextrin-glucosidase	unknown	unknown	gnl\|CDD\|236759
NZ_CP043942.1\|WP_001221319.1\|3637364_3638567_+\|exonuclease-subunit-SbcD	unknown	unknown	gnl\|CDD\|182871
NZ_CP043942.1\|WP_000193393.1\|3647387_3647912_-\|shikimate-kinase-AroL	unknown	unknown	gnl\|CDD\|235153
NZ_CP043942.1\|WP_001009885.1\|3629398_3629980_+\|ACP-phosphodiesterase	unknown	unknown	gnl\|CDD\|182207
NZ_CP043942.1\|WP_001276420.1\|3646211_3646889_-\|AroM-family-protein	unknown	unknown	gnl\|CDD\|182491
NZ_CP043942.1\|WP_001142439.1\|3647146_3647338_-\|protein-YaiA	unknown	unknown	gnl\|CDD\|182421
NZ_CP043942.1\|WP_001295331.1\|3648584_3649394_+\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
NZ_CP043942.1\|WP_001266503.1\|3628235_3629306_-\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	unknown	unknown	gnl\|CDD\|234666
NZ_CP043942.1\|WP_001295329.1\|3631957_3633331_-\|proline-specific-permease-ProY	unknown	unknown	gnl\|CDD\|182566
NZ_CP043942.1\|WP_000113933.1\|3636485_3637175_-\|phosphate-response-regulator-transcription-factor-PhoB	unknown	unknown	gnl\|CDD\|182277
NZ_CP043942.1\|WP_000893623.1\|3635132_3636428_-\|phosphate-regulon-sensor-histidine-kinase-PhoR	unknown	unknown	gnl\|CDD\|182895
NZ_CP043942.1\|WP_001219309.1\|3643264_3644173_-\|fructokinase	unknown	unknown	gnl\|CDD\|236565
NZ_CP043942.1\|WP_001326926.1\|3641835_3643020_+\|MFS-transporter-AraJ	unknown	unknown	gnl\|CDD\|182234
NZ_CP043942.1\|WP_072240804.1\|3648094_3648457_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_CP043942.1\|WP_000941942.1\|3645855_3646140_-\|pyrimidine/purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|182565
NZ_CP043942.1\|WP_120795376.1\|3645286_3645370_-\|protein-YkiD	unknown	unknown	unknown
NZ_CP043942.1\|WP_000484048.1\|3649410_3650526_-\|diguanylate-cyclase-AdrA	unknown	unknown	gnl\|CDD\|182329
NZ_CP043942.1\|WP_000149639.1\|3633406_3634726_-\|branched-chain-amino-acid-transporter-carrier-protein-BrnQ	unknown	unknown	gnl\|CDD\|185331
NZ_CP043942.1\|WP_000698951.1\|3638563_3641710_+\|exonuclease-subunit-SbcC	unknown	unknown	gnl\|CDD\|182330
NZ_CP043942.1\|WP_001298537.1\|3644297_3645209_+\|recombination-associated-protein-RdgC	unknown	unknown	gnl\|CDD\|225521

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_001310597.1\|3629984_3631802_-\|maltodextrin-glucosidase	gnl\|CDD\|236759	PRK10785, PRK10785, maltodextrin glucosidase; Provisional.	0
NZ_CP043942.1\|WP_001221319.1\|3637364_3638567_+\|exonuclease-subunit-SbcD	gnl\|CDD\|182871	PRK10966, PRK10966, exonuclease subunit SbcD; Provisional.	0
NZ_CP043942.1\|WP_000193393.1\|3647387_3647912_-\|shikimate-kinase-AroL	gnl\|CDD\|235153	PRK03731, aroL, shikimate kinase AroL.	2.43812e-108
NZ_CP043942.1\|WP_001009885.1\|3629398_3629980_+\|ACP-phosphodiesterase	gnl\|CDD\|182207	PRK10045, PRK10045, ACP phosphodiesterase.	3.03368e-136
NZ_CP043942.1\|WP_001276420.1\|3646211_3646889_-\|AroM-family-protein	gnl\|CDD\|182491	PRK10481, PRK10481, hypothetical protein; Provisional.	2.13662e-120
NZ_CP043942.1\|WP_001142439.1\|3647146_3647338_-\|protein-YaiA	gnl\|CDD\|182421	PRK10380, PRK10380, hypothetical protein; Provisional.	5.14477e-31
NZ_CP043942.1\|WP_001295331.1\|3648584_3649394_+\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.87564e-128
NZ_CP043942.1\|WP_001266503.1\|3628235_3629306_-\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	gnl\|CDD\|234666	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional.	0
NZ_CP043942.1\|WP_001295329.1\|3631957_3633331_-\|proline-specific-permease-ProY	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
NZ_CP043942.1\|WP_000113933.1\|3636485_3637175_-\|phosphate-response-regulator-transcription-factor-PhoB	gnl\|CDD\|182277	PRK10161, PRK10161, phosphate response regulator transcription factor PhoB.	5.1688e-159
NZ_CP043942.1\|WP_000893623.1\|3635132_3636428_-\|phosphate-regulon-sensor-histidine-kinase-PhoR	gnl\|CDD\|182895	PRK11006, phoR, phosphate regulon sensor histidine kinase PhoR.	0
NZ_CP043942.1\|WP_001219309.1\|3643264_3644173_-\|fructokinase	gnl\|CDD\|236565	PRK09557, PRK09557, fructokinase; Reviewed.	0
NZ_CP043942.1\|WP_001326926.1\|3641835_3643020_+\|MFS-transporter-AraJ	gnl\|CDD\|182234	PRK10091, PRK10091, MFS transport protein AraJ; Provisional.	0
NZ_CP043942.1\|WP_072240804.1\|3648094_3648457_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	3.04641e-60
NZ_CP043942.1\|WP_000941942.1\|3645855_3646140_-\|pyrimidine/purine-nucleoside-phosphorylase	gnl\|CDD\|182565	PRK10579, PRK10579, pyrimidine/purine nucleoside phosphorylase.	5.85948e-64
NZ_CP043942.1\|WP_000484048.1\|3649410_3650526_-\|diguanylate-cyclase-AdrA	gnl\|CDD\|182329	PRK10245, adrA, diguanylate cyclase AdrA; Provisional.	0
NZ_CP043942.1\|WP_000149639.1\|3633406_3634726_-\|branched-chain-amino-acid-transporter-carrier-protein-BrnQ	gnl\|CDD\|185331	PRK15433, PRK15433, branched-chain amino acid transporter carrier protein BrnQ.	0
NZ_CP043942.1\|WP_000698951.1\|3638563_3641710_+\|exonuclease-subunit-SbcC	gnl\|CDD\|182330	PRK10246, PRK10246, exonuclease subunit SbcC; Provisional.	0
NZ_CP043942.1\|WP_001298537.1\|3644297_3645209_+\|recombination-associated-protein-RdgC	gnl\|CDD\|225521	COG2974, RdgC, DNA recombination-dependent growth factor C [DNA replication, recombination, and repair].	0

>NZ_CP043942.1|WP_001326926.1|3641835_3643020_+|MFS-transporter-AraJ
MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGNLREQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADTPVLAKPLG
>NZ_CP043942.1|WP_000698951.1|3638563_3641710_+|exonuclease-subunit-SbcC
MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAVK
>NZ_CP043942.1|WP_001221319.1|3637364_3638567_+|exonuclease-subunit-SbcD
MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYIALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLHTLAGEHEA
>NZ_CP043942.1|WP_000113933.1|3636485_3637175_-|phosphate-response-regulator-transcription-factor-PhoB
MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF
>NZ_CP043942.1|WP_000893623.1|3635132_3636428_-|phosphate-regulon-sensor-histidine-kinase-PhoR
MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRDFSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNEKVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD
>NZ_CP043942.1|WP_000149639.1|3633406_3634726_-|branched-chain-amino-acid-transporter-carrier-protein-BrnQ
MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTAAFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRTATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALVILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGVTEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFGGGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLSQLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAFSDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH
>NZ_CP043942.1|WP_001295329.1|3631957_3633331_-|proline-specific-permease-ProY
MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHDRQLAENQ
>NZ_CP043942.1|WP_001310597.1|3629984_3631802_-|maltodextrin-glucosidase
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEVVLPASPFLNAVQWQCKEGHGQLTDGILALPAISATVWMN
>NZ_CP043942.1|WP_001009885.1|3629398_3629980_+|ACP-phosphodiesterase
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASRKAL
>NZ_CP043942.1|WP_001266503.1|3628235_3629306_-|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA
MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
>NZ_CP043942.1|WP_001219309.1|3643264_3644173_-|fructokinase
MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIATLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRLANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPLPWMDEDELRYREEVPCYCGKQGCIETFISGTGFAMDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGECETPVRKAKHGDSSGVRGAAWLWPQE
>NZ_CP043942.1|WP_001298537.1|3644297_3645209_+|recombination-associated-protein-RdgC
MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
>NZ_CP043942.1|WP_120795376.1|3645286_3645370_-|protein-YkiD
MTQRPWSKLQRKTHNIAALKIIARRSE
>NZ_CP043942.1|WP_000941942.1|3645855_3646140_-|pyrimidine/purine-nucleoside-phosphorylase
MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
>NZ_CP043942.1|WP_001276420.1|3646211_3646889_-|AroM-family-protein
MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREEVMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANISSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSLGNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIARLAAELLV
>NZ_CP043942.1|WP_001142439.1|3647146_3647338_-|protein-YaiA
MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEHPTAQEAMDAKKRYEDPDKE
>NZ_CP043942.1|WP_000193393.1|3647387_3647912_-|shikimate-kinase-AroL
MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
>NZ_CP043942.1|WP_072240804.1|3648094_3648457_-|YaiI/YqxD-family-protein
MGGCRRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
>NZ_CP043942.1|WP_001295331.1|3648584_3649394_+|pyrroline-5-carboxylate-reductase
MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS
>NZ_CP043942.1|WP_000484048.1|3649410_3650526_-|diguanylate-cyclase-AdrA
MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA

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Crispr_ID: NZ_CP043942_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043942_9

4207720-4207869

Orphan

Consensus_repeat	Method
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP043942_9

>merge|NZ_CP043942|9|4207720-4207869|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCATGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

>NZ_CP043942|9|9|4207720-4207869|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCA
TGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043942.1\|WP_001246998.1\|4196931_4197291_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_000455467.1\|4197929_4198160_-\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|225848
NZ_CP043942.1\|WP_000584114.1\|4204804_4205905_-\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP043942.1\|WP_000397144.1\|4206171_4207683_+\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP043942.1\|WP_001118619.1\|4215081_4216005_+\|IS5-like-element-IS903B-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP043942.1\|WP_001066505.1\|4198537_4199176_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_111530674.1\|4197283_4197868_-\|host-cell-division-inhibitor-Icd-like-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_000002954.1\|4213315_4213732_-\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP043942.1\|WP_000416404.1\|4208479_4211335_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP043942.1\|WP_111530660.1\|4216050_4216356_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_000786399.1\|4208036_4208480_+\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP043942.1\|WP_001014711.1\|4211386_4212574_-\|DUF898-family-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP043942.1\|WP_001333753.1\|4216342_4217764_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043942.1\|WP_001294554.1\|4202059_4203562_+\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP043942.1\|WP_000772653.1\|4199205_4200468_-\|integrase-arm-type-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
NZ_CP043942.1\|WP_001333751.1\|4212766_4213270_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP043942.1\|WP_000012906.1\|4213893_4214898_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP043942.1\|WP_001295681.1\|4203722_4204805_-\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP043942.1\|WP_001299662.1\|4200912_4201932_+\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP043942.1\|WP_001333754.1\|4217886_4218339_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345

Protein	Function_ID	Function_description	E-value
NZ_CP043942.1\|WP_000002954.1\|4213315_4213732_-\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	8.03891e-69
NZ_CP043942.1\|WP_000455467.1\|4197929_4198160_-\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	2.99457e-15
NZ_CP043942.1\|WP_000584114.1\|4204804_4205905_-\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP043942.1\|WP_000397144.1\|4206171_4207683_+\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP043942.1\|WP_001118619.1\|4215081_4216005_+\|IS5-like-element-IS903B-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.1599e-57
NZ_CP043942.1\|WP_000416404.1\|4208479_4211335_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP043942.1\|WP_001333751.1\|4212766_4213270_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.71083e-18
NZ_CP043942.1\|WP_001014711.1\|4211386_4212574_-\|DUF898-family-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	3.73478e-110
NZ_CP043942.1\|WP_001294554.1\|4202059_4203562_+\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP043942.1\|WP_000772653.1\|4199205_4200468_-\|integrase-arm-type-DNA-binding-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	6.37182e-82
NZ_CP043942.1\|WP_000786399.1\|4208036_4208480_+\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP043942.1\|WP_000012906.1\|4213893_4214898_+\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP043942.1\|WP_001295681.1\|4203722_4204805_-\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP043942.1\|WP_001299662.1\|4200912_4201932_+\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	8.44277e-169
NZ_CP043942.1\|WP_001333754.1\|4217886_4218339_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	4.50803e-70

>NZ_CP043942.1|WP_000397144.1|4206171_4207683_+|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP043942.1|WP_000584114.1|4204804_4205905_-|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP043942.1|WP_001295681.1|4203722_4204805_-|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP043942.1|WP_001294554.1|4202059_4203562_+|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLTLEQQGATHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASTEQQNNPAVKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP043942.1|WP_001299662.1|4200912_4201932_+|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
>NZ_CP043942.1|WP_000772653.1|4199205_4200468_-|integrase-arm-type-DNA-binding-domain-containing-protein
MKLNARQIETAKPKEKAYKMADGGGLYLEVSPKGSKYWRMKYRRPSDKKEDRLAFGVYPTVTLAEARGKRDAAKKLLSQGIDPKAEQKGAQAEIEGAYLFETIARQWHASNLTWSEDHSRRVLLTLEQYIFPSIGQIDARTLRTSQLLNPIKAVDTAGKHDVAQRLMQRVTAIMRFGVQNDLLESNPACDMAGALLSVKATHHPALPPKRIPELLERLSRYKGRLMTRLAVELTLLTFIRSSEMRFARWSEVNFERSEWTIPGIRKPIPGVKHSERGMKMKTEHIVPLSKQAFDIFKRLHALSGKGEVIFPSDHDPKKVMSENTVNNALRVMGYDTKTEVCGHGFRTMARGALSESKLWNDDAIERQLSHVERKNVKGSYMHTSEYLEERRLMLQWWADYIDANKNGSVTPYDFARMHGK
>NZ_CP043942.1|WP_001066505.1|4198537_4199176_-|hypothetical-protein
MNNTQFDNNLFYFNRLTYITPHEVALAMNGFDYDTENDELTEVQLKEVIRLRKAITRNLQLINEYKNVSATQKVEANLLLTAAYIFQREGIVPVEIKERIENALRQQVKNKDWSDILMTLGGSELYEVGKKLRSNGRGQYRKDDEDNYSCKLIYLLIELLKRHGKVSYSDNSVIYNDIVSFCNENEILMKGVKKATFYKKIKLGKDIIKYGE
>NZ_CP043942.1|WP_000455467.1|4197929_4198160_-|AlpA-family-phage-regulatory-protein
MEYANSFSDNQTLISAKEVLRRVQRSKAWLYKQLANNTFPRPVKIGTRAISFVESEVDHWIQEQIYASRGERYENH
>NZ_CP043942.1|WP_111530674.1|4197283_4197868_-|host-cell-division-inhibitor-Icd-like-protein
METERTSVGFSIQLPCSGLFFLRCRRLISPFTAVTMNCAFVSPSSRLLSNSATTSCGKRALSCCDLLLVELVAITGSPRVRCDSVYAKKMIIKSLKCDSLKGSFKIKGAIHLVSAKPDSAATLTGLLTNPLNEVTKMAKQKCTWLFAAINRSQRNTRPVMLRITADNERSARRRLAPDYVLSFAGRIPCGGEHA
>NZ_CP043942.1|WP_001246998.1|4196931_4197291_-|hypothetical-protein
MRNYPHPGERWQHERGWTVTIIRLIEASPSVALVNPEFSCEVLIRHDSDNQLSSCPLAWFEQRYTRLFDVPLLKPAPAPAGGSGSGPLTLHPSVLFIRWRERSIRRSAEPDDGHYSKFL
>NZ_CP043942.1|WP_000786399.1|4208036_4208480_+|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP043942.1|WP_000416404.1|4208479_4211335_+|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIDGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP043942.1|WP_001014711.1|4211386_4212574_-|DUF898-family-protein
MNGVNVGKDNPRHAFVFTGKGGEYFLICLVNFLLTIITLGIYGPWALVKCRRYICQHVTLKGQPFSYKGTGGAIFVSMLLIMVVYFLSISCVAGQHFVLAFLLFALLICGIPCMAVKSLQYQANMTSLNGIRFGFNCSMLRAWWVMLGLPVLLALAFWLVLYLIAQVTTSIGGLFFNLVVLSLLSVIGLGVINGITYSKWMPLLGNNATFGVHQFSIKVNVKECIKGCMLAILTMVPFIIVIGIMIAPVFQQLIMMSMLGQSEAGGELILQYYPQIMASYFLYFVAILVFASYLYVTLRSLFLNNLTLANGTIRFHSSVTTFGMLLRMLAVLMGSSITCGLAYPWLKMWMVSWIANNTHVQGDLDSLELTNDDKPQDSGPLMWISRGIMPYVPFI
>NZ_CP043942.1|WP_001333751.1|4212766_4213270_+|GNAT-family-N-acetyltransferase
MNVVASPALRLRKLTVADNPAIASVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>NZ_CP043942.1|WP_000002954.1|4213315_4213732_-|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEEDDGVRH
>NZ_CP043942.1|WP_000012906.1|4213893_4214898_+|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNNKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSN
>NZ_CP043942.1|WP_001118619.1|4215081_4216005_+|IS5-like-element-IS903B-family-transposase
MAKQKFKITNWPTYNKALINRGSITFWLDDEAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLRCPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRKLHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHDELRRKKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVKQLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA
>NZ_CP043942.1|WP_111530660.1|4216050_4216356_-|hypothetical-protein
MKQPDFAKWYFYQLLKSYEGEQMYLNELGYVYGDEEKKEIVNKLPGYVVKIFEEKIDNELKIRTRMMETLRDGKINIYDYINEKQLEKLNPPQDLRSARLC
>NZ_CP043942.1|WP_001333753.1|4216342_4217764_-|hypothetical-protein
MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNDFARNAEGQDNTRNILDPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKFVMNNPEGERADLSKVEIEITLSTITTMGTRQGHTAIIFPQPDGLTNRYEGKSFERKDESSLHLITNKVLACYQREANKEVALLLNNHQKLNYRQKLNNSQGLNNSQGLNNSQGLNNSQELNDSQELNDSQDLNNSQVSCKGSVDSTITDLLEKPLNNALLAIRKEHLLLMPHVCDESISYLLGEKGILEEIDKLYALNDHGIDNDKVGNNEINDIKVNLSHILIDSLDDAKVNLTPVIDSILETFSKSPYINDVRILDWCFNKSMQYFGDSEKITHACSVMSHIDFDCNQSKIAETLFFNLDKEPYKNSRELQELIWEKLVAYVNVFNLSNQEKSRLILRLFDDVKLLFNEVPVSILVNDIFLKVFFHEAT
>NZ_CP043942.1|WP_001333754.1|4217886_4218339_-|YhcH/YjgK/YiaL-family-protein
MIIGNIHNLQPWLPQELRQAIEHVKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP043942_5	5.1\|2991364\|40\|NZ_CP043942\|CRISPRCasFinder	2991364-2991403	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NZ_CP043942_4	4.1\|2321106\|38\|NZ_CP043942\|CRISPRCasFinder	2321106-2321143	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP043942_2	2.5\|1110470\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110470-1110501	32	NC_021229	Arthrobacter nicotinovorans pAO1 megaplasmid sequence, strain ATCC 49919	65474-65505	5	0.844
NZ_CP043942_1	1.7\|1084403\|31\|NZ_CP043942\|CRISPRCasFinder	1084403-1084433	31	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	755174-755204	6	0.806
NZ_CP043942_1	1.7\|1084403\|31\|NZ_CP043942\|CRISPRCasFinder	1084403-1084433	31	MH067970	Arthrobacter sp. strain ANT_H40 plasmid pA40H1, complete sequence	47826-47856	6	0.806
NZ_CP043942_2	2.5\|1110470\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110470-1110501	32	NZ_CP017422	Arthrobacter sp. ZXY-2 plasmid pZXY21, complete sequence	208287-208318	6	0.812
NZ_CP043942_1	1.10\|1084586\|31\|NZ_CP043942\|CRISPRCasFinder	1084586-1084616	31	MG945629	UNVERIFIED: Microviridae sp. isolate 6200-1602, complete genome	4209-4239	7	0.774
NZ_CP043942_1	1.10\|1084586\|31\|NZ_CP043942\|CRISPRCasFinder	1084586-1084616	31	MK814759	Gordonia phage Reyja, complete genome	4468-4498	7	0.774
NZ_CP043942_2	2.6\|1110531\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110531-1110562	32	MK416018	Klebsiella phage ST147-VIM1phi7.1, complete genome	24790-24821	7	0.781
NZ_CP043942_2	2.7\|1110592\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110592-1110623	32	MF351863	Synechococcus phage Bellamy, complete genome	123998-124029	7	0.781
NZ_CP043942_1	1.2\|1084401\|33\|NZ_CP043942\|PILER-CR,CRT	1084401-1084433	33	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	755172-755204	8	0.758
NZ_CP043942_1	1.7\|1084403\|31\|NZ_CP043942\|CRISPRCasFinder	1084403-1084433	31	NZ_CP007070	Rhizobium leguminosarum bv. trifolii CB782 plasmid unnamed, complete sequence	191920-191950	8	0.742
NZ_CP043942_1	1.9\|1084525\|31\|NZ_CP043942\|CRISPRCasFinder	1084525-1084555	31	NZ_CP033579	Vibrio mediterranei strain 117-T6 plasmid unnamed, complete sequence	47369-47399	8	0.742
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	375744-375776	8	0.758
NZ_CP043942_2	2.5\|1110470\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110470-1110501	32	MK113951	Phage 5P_3, complete genome	11967-11998	8	0.75
NZ_CP043942_2	2.5\|1110470\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110470-1110501	32	AP017924	Ralstonia phage RP12 DNA, complete genome	11643-11674	8	0.75
NZ_CP043942_2	2.11\|1110836\|32\|NZ_CP043942\|CRISPRCasFinder,CRT	1110836-1110867	32	NZ_AP018516	Acetobacter orientalis strain FAN1 plasmid pAOF1, complete sequence	48296-48327	8	0.75
NZ_CP043942_1	1.6\|1084342\|31\|NZ_CP043942\|CRISPRCasFinder	1084342-1084372	31	MF158039	Shigella phage Sf12, complete genome	4976-5006	9	0.71
NZ_CP043942_1	1.6\|1084342\|31\|NZ_CP043942\|CRISPRCasFinder	1084342-1084372	31	MF158042	Shigella phage Sd1, complete genome	939-969	9	0.71
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_CP010957	Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence	26182-26214	9	0.727
NZ_CP043942_2	2.6\|1110531\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110531-1110562	32	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	1143591-1143622	9	0.719
NZ_CP043942_2	2.6\|1110531\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110531-1110562	32	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	891493-891524	9	0.719
NZ_CP043942_2	2.6\|1110531\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110531-1110562	32	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	1143594-1143625	9	0.719
NZ_CP043942_2	2.6\|1110531\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110531-1110562	32	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	315030-315061	9	0.719
NZ_CP043942_2	2.6\|1110531\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110531-1110562	32	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	1123532-1123563	9	0.719
NZ_CP043942_1	1.6\|1084342\|31\|NZ_CP043942\|CRISPRCasFinder	1084342-1084372	31	MT840185	Bacteriophage sp. Joined_contig_19 genomic sequence	64310-64340	10	0.677
NZ_CP043942_1	1.6\|1084342\|31\|NZ_CP043942\|CRISPRCasFinder	1084342-1084372	31	KF356199	Microcystis phage MaMV-DC, complete genome	50157-50187	10	0.677
NZ_CP043942_1	1.6\|1084342\|31\|NZ_CP043942\|CRISPRCasFinder	1084342-1084372	31	NC_008562	Microcystis phage Ma-LMM01 DNA, complete genome	44744-44774	10	0.677
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	CP046443	Pseudomonas coronafaciens pv. coronafaciens strain B19001 plasmid unnamed2, complete sequence	31933-31965	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_LT963392	Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence	103013-103045	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_LT963392	Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence	110510-110542	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_CP034079	Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-1, complete sequence	48454-48486	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_CP034080	Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-2, complete sequence	39480-39512	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NC_005918	Pseudomonas syringae pv. maculicola strain ES4326 plasmid pPMA4326A, complete sequence	31117-31149	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_CP047262	Pseudomonas syringae pv. maculicola str. ES4326 plasmid pPma4326A, complete sequence	30966-30998	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_CP026560	Pseudomonas amygdali pv. morsprunorum strain R15244 plasmid p3_tig5, complete sequence	19118-19150	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_LT963406	Pseudomonas syringae pv. avii isolate CFBP3846 plasmid PP4, complete sequence	54820-54852	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	LT985193	Pseudomonas syringae strain CFBP 2116 genome assembly, plasmid: PP2	32077-32109	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_LT963393	Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP2, complete sequence	50597-50629	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_LT985210	Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP1, complete sequence	105842-105874	10	0.697
NZ_CP043942_2	2.2\|1110286\|33\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110286-1110318	33	NZ_LT985211	Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP2, complete sequence	84272-84304	10	0.697
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NZ_CP028970	Aminobacter sp. MSH1 plasmid pUSP2, complete sequence	156123-156154	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NZ_CP053984	Achromobacter pestifer strain FDAARGOS_790 plasmid unnamed, complete sequence	21888-21919	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_010935	Comamonas testosteroni CNB-1 plasmid pCNB, complete sequence	28766-28797	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	JX469826	Uncultured bacterium plasmid pB12, complete sequence	11283-11314	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	JN106171	Uncultured bacterium plasmid pAKD26, complete sequence	11289-11320	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_016968	Comamonas testosteroni plasmid pTB30, complete sequence	11287-11318	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_016978	Comamonas testosteroni plasmid pI2, complete sequence	11272-11303	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NZ_CP017760	Cupriavidus necator strain NH9 plasmid pENH91, complete sequence	67078-67109	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NZ_CP053554	Diaphorobacter sp. JS3050 plasmid pDCNB, complete sequence	4235-4266	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_019263	Delftia acidovorans plasmid pLME1, complete sequence	11288-11319	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_019264	Delftia acidovorans plasmid pNB8c, complete sequence	11288-11319	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_019283	Delftia acidovorans plasmid pC1-1, complete sequence	11288-11319	10	0.688
NZ_CP043942_2	2.4\|1110409\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110409-1110440	32	NC_006830	Achromobacter xylosoxidans A8 plasmid pA81, complete sequence	11350-11381	10	0.688
NZ_CP043942_2	2.5\|1110470\|32\|NZ_CP043942\|PILER-CR,CRISPRCasFinder,CRT	1110470-1110501	32	NC_002580	Propionibacterium freudenreichii plasmid p545, complete sequence	2898-2929	10	0.688
NZ_CP043942_8	8.1\|3643140\|59\|NZ_CP043942\|CRISPRCasFinder	3643140-3643198	59	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	97-155	10	0.831
NZ_CP043942_1	1.1\|1084340\|33\|NZ_CP043942\|PILER-CR,CRT	1084340-1084372	33	MF158039	Shigella phage Sf12, complete genome	4974-5006	11	0.667
NZ_CP043942_1	1.1\|1084340\|33\|NZ_CP043942\|PILER-CR,CRT	1084340-1084372	33	MF158042	Shigella phage Sd1, complete genome	937-969	11	0.667
NZ_CP043942_8	8.1\|3643140\|59\|NZ_CP043942\|CRISPRCasFinder	3643140-3643198	59	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	40375-40433	11	0.814

1. spacer 5.1|2991364|40|NZ_CP043942|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 4.1|2321106|38|NZ_CP043942|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

3. spacer 2.5|1110470|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_021229 (Arthrobacter nicotinovorans pAO1 megaplasmid sequence, strain ATCC 49919) position: , mismatch: 5, identity: 0.844

-ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
tccgctcg-gcaggctgcaacgcaagccgccca	Protospacer
 *.*** * ** ******** ************

4. spacer 1.7|1084403|31|NZ_CP043942|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.806

cgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
cgtggtcgtgggtgctgctgttgctggagcg	Protospacer
*******.**************** *.. *.

5. spacer 1.7|1084403|31|NZ_CP043942|CRISPRCasFinder matches to MH067970 (Arthrobacter sp. strain ANT_H40 plasmid pA40H1, complete sequence) position: , mismatch: 6, identity: 0.806

cgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
cgtggtcaagggtgctgctgttcccacgcct	Protospacer
******** ************* * . ***

6. spacer 2.5|1110470|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017422 (Arthrobacter sp. ZXY-2 plasmid pZXY21, complete sequence) position: , mismatch: 6, identity: 0.812

-ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
tccgctcg-gcaggctgcaacgcaagccgcccc	Protospacer
 *.*** * ** ******** ***********

7. spacer 1.10|1084586|31|NZ_CP043942|CRISPRCasFinder matches to MG945629 (UNVERIFIED: Microviridae sp. isolate 6200-1602, complete genome) position: , mismatch: 7, identity: 0.774

agcctgacgagactactgaggccgttctgtc	CRISPR spacer
aaaaggccaagactactgaggccgttcagtc	Protospacer
*.   * *.****************** ***

8. spacer 1.10|1084586|31|NZ_CP043942|CRISPRCasFinder matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 7, identity: 0.774

agcctgacgagactactgaggccgttctgtc-	CRISPR spacer
agcctgacgaggctactggggcca-gcggtgg	Protospacer
***********.******.****.  * **

9. spacer 2.6|1110531|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to MK416018 (Klebsiella phage ST147-VIM1phi7.1, complete genome) position: , mismatch: 7, identity: 0.781

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
cccatcagcgcgttttttggcggtgtgatgga	Protospacer
****.************** *** *. **.*

10. spacer 2.7|1110592|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to MF351863 (Synechococcus phage Bellamy, complete genome) position: , mismatch: 7, identity: 0.781

ttgaactcaccacgattgttaatatggacgat	CRISPR spacer
aaggtatcaccacgattgttgatatgggcgat	Protospacer
  *.  **************.******.****

11. spacer 1.2|1084401|33|NZ_CP043942|PILER-CR,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.758

gacgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
tccgtggtcgtgggtgctgctgttgctggagcg	Protospacer
  *******.**************** *.. *.

12. spacer 1.7|1084403|31|NZ_CP043942|CRISPRCasFinder matches to NZ_CP007070 (Rhizobium leguminosarum bv. trifolii CB782 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

cgtggtcatgggtgctgctgttgcagagcca	CRISPR spacer
tgcggtcatggatgctgatgttgcagtgatg	Protospacer
.*.********.***** ******** * ..

13. spacer 1.9|1084525|31|NZ_CP043942|CRISPRCasFinder matches to NZ_CP033579 (Vibrio mediterranei strain 117-T6 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

atagcaatagtccatagatttgcgaaaacag	CRISPR spacer
aggtttgtagtccattgatttgcgaaaactg	Protospacer
* . . .******** ************* *

14. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 8, identity: 0.758

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ctgatcgcgcattacctgcgcgtcgccgacgcg	Protospacer
* .*********  ************** *

15. spacer 2.5|1110470|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to MK113951 (Phage 5P_3, complete genome) position: , mismatch: 8, identity: 0.75

ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
gagcatcggctggctgcaaggcaagctgcccc	Protospacer
  **   .******************.****

16. spacer 2.5|1110470|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to AP017924 (Ralstonia phage RP12 DNA, complete genome) position: , mismatch: 8, identity: 0.75

ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
gcggaagcgctggctgcacggcaagcggccca	Protospacer
 .*  .* ********** ******* *****

17. spacer 2.11|1110836|32|NZ_CP043942|CRISPRCasFinder,CRT matches to NZ_AP018516 (Acetobacter orientalis strain FAN1 plasmid pAOF1, complete sequence) position: , mismatch: 8, identity: 0.75

gcaacgacggtgagatttcacgcctgacgctg	CRISPR spacer
tcaacgacggtaagatgtcacgcctaaagaat	Protospacer
 **********.**** ********.* *

18. spacer 1.6|1084342|31|NZ_CP043942|CRISPRCasFinder matches to MF158039 (Shigella phage Sf12, complete genome) position: , mismatch: 9, identity: 0.71

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
tgtttgcagcattaacgctccccaagtgccg	Protospacer
*******.************ ***.   ..

19. spacer 1.6|1084342|31|NZ_CP043942|CRISPRCasFinder matches to MF158042 (Shigella phage Sd1, complete genome) position: , mismatch: 9, identity: 0.71

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
tgtttgcagcattaacgctctccaagtgccg	Protospacer
*******.************ ***.   ..

20. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010957 (Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence) position: , mismatch: 9, identity: 0.727

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ctcgacccgcataccttgcgtgtcgccgcctcg	Protospacer
*  . * ********.****.**********

21. spacer 2.6|1110531|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

22. spacer 2.6|1110531|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

23. spacer 2.6|1110531|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

24. spacer 2.6|1110531|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

25. spacer 2.6|1110531|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 9, identity: 0.719

cccaccagcgcgttttttgccggggccatagt	CRISPR spacer
gccacccgcgctttttttgccgggccggatat	Protospacer
 ***** **** ************ * .  .*

26. spacer 1.6|1084342|31|NZ_CP043942|CRISPRCasFinder matches to MT840185 (Bacteriophage sp. Joined_contig_19 genomic sequence) position: , mismatch: 10, identity: 0.677

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
gtgcggcggcattaatgctcacaagtatggt	Protospacer
   . **********.****** *****  .

27. spacer 1.6|1084342|31|NZ_CP043942|CRISPRCasFinder matches to KF356199 (Microcystis phage MaMV-DC, complete genome) position: , mismatch: 10, identity: 0.677

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
gtgcggcggcattaatgctcacaagtatggt	Protospacer
   . **********.****** *****  .

28. spacer 1.6|1084342|31|NZ_CP043942|CRISPRCasFinder matches to NC_008562 (Microcystis phage Ma-LMM01 DNA, complete genome) position: , mismatch: 10, identity: 0.677

tgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
gtgcggcggcattaatgctcacaagtatggt	Protospacer
   . **********.****** *****  .

29. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to CP046443 (Pseudomonas coronafaciens pv. coronafaciens strain B19001 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

30. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963392 (Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

31. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963392 (Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

32. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034079 (Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

33. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034080 (Pseudomonas syringae pv. pisi str. PP1 plasmid pPP1-2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

34. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_005918 (Pseudomonas syringae pv. maculicola strain ES4326 plasmid pPMA4326A, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

35. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047262 (Pseudomonas syringae pv. maculicola str. ES4326 plasmid pPma4326A, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

36. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026560 (Pseudomonas amygdali pv. morsprunorum strain R15244 plasmid p3_tig5, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

37. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963406 (Pseudomonas syringae pv. avii isolate CFBP3846 plasmid PP4, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

38. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to LT985193 (Pseudomonas syringae strain CFBP 2116 genome assembly, plasmid: PP2) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

39. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963393 (Pseudomonas syringae pv. cerasicola isolate CFBP6109 plasmid PP2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

40. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT985210 (Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP1, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

41. spacer 2.2|1110286|33|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT985211 (Pseudomonas syringae pv. cerasicola strain CFBP 6110 plasmid PP2, complete sequence) position: , mismatch: 10, identity: 0.697

cgaatcgcgcataccctgcgcgtcgccgcctgc	CRISPR spacer
ttcgctgcgcatctcctgcgcgtcgccgccggt	Protospacer
.  ...****** .**************** *.

42. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028970 (Aminobacter sp. MSH1 plasmid pUSP2, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
acgtcaccccggaagcgattgccagcacacgc	Protospacer
.  ********.*** **********  .* .

43. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053984 (Achromobacter pestifer strain FDAARGOS_790 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

44. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_010935 (Comamonas testosteroni CNB-1 plasmid pCNB, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

45. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to JX469826 (Uncultured bacterium plasmid pB12, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

46. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to JN106171 (Uncultured bacterium plasmid pAKD26, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

47. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_016968 (Comamonas testosteroni plasmid pTB30, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

48. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_016978 (Comamonas testosteroni plasmid pI2, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

49. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017760 (Cupriavidus necator strain NH9 plasmid pENH91, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

50. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053554 (Diaphorobacter sp. JS3050 plasmid pDCNB, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

51. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_019263 (Delftia acidovorans plasmid pLME1, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

52. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_019264 (Delftia acidovorans plasmid pNB8c, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

53. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_019283 (Delftia acidovorans plasmid pC1-1, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

54. spacer 2.4|1110409|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_006830 (Achromobacter xylosoxidans A8 plasmid pA81, complete sequence) position: , mismatch: 10, identity: 0.688

gactcaccccgaaagagattgccagccagctt	CRISPR spacer
aggtactgacgaatgagaatgccagccagctt	Protospacer
.. *  .  **** **** *************

55. spacer 2.5|1110470|32|NZ_CP043942|PILER-CR,CRISPRCasFinder,CRT matches to NC_002580 (Propionibacterium freudenreichii plasmid p545, complete sequence) position: , mismatch: 10, identity: 0.688

ctgctggagctggctgcaaggcaagccgccca	CRISPR spacer
ccctgagagctggctgccacgcaagccgctgg	Protospacer
*. . .*********** * *********. .

56. spacer 8.1|3643140|59|NZ_CP043942|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 10, identity: 0.831

-cggagcacttattgccggatgcggcgtgaacgccttatccggcctacggttctggcacc	CRISPR spacer
tcagtgcac-gatcgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctc	Protospacer
 *.* ****  **.**************************** ************   .*

57. spacer 1.1|1084340|33|NZ_CP043942|PILER-CR,CRT matches to MF158039 (Shigella phage Sf12, complete genome) position: , mismatch: 11, identity: 0.667

tgtgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
attgtttgcagcattaacgctccccaagtgccg	Protospacer
  *******.************ ***.   ..

58. spacer 1.1|1084340|33|NZ_CP043942|PILER-CR,CRT matches to MF158042 (Shigella phage Sd1, complete genome) position: , mismatch: 11, identity: 0.667

tgtgtttgcggcattaacgctcaccagtatttc	CRISPR spacer
attgtttgcagcattaacgctctccaagtgccg	Protospacer
  *******.************ ***.   ..

59. spacer 8.1|3643140|59|NZ_CP043942|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 11, identity: 0.814

cggagcacttattgccggatgcggcgtgaacgccttatccggcctacggttctggcacc-	CRISPR spacer
ggtacggctttttgccggatgcggcgtaaacgccttatccggcctacggtt-tggtgcga	Protospacer
 * *  .*** ****************.*********************** ***..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1118322 : 1131505

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001295182.1\|1118322_1119084_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.4e-59	48.0
WP_000254708.1\|1119077_1119704_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.7e-36	49.7
WP_001272592.1\|1119843_1120983_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	1.7e-06	35.6
WP_000081550.1\|1121045_1122038_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.1e-32	37.6
WP_000104441.1\|1122131_1123496_-	GntP family transporter	NA	NA	NA	NA
WP_001136934.1\|1123584_1124361_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_001278994.1\|1124365_1125004_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590403.1\|1125000_1126263_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	1.7e-135	61.4
WP_000847984.1\|1126259_1127168_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	5.1e-118	76.5
WP_001300386.1\|1127363_1128131_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	7.4e-70	56.3
WP_001141322.1\|1128181_1128838_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	6.2e-49	46.3
WP_039023140.1\|1128943_1131505_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	3.0e-30	20.6

DBSCAN-SWA_2

1648884 : 1712331

Enterobacteria_phage(39.22%)

head,protease,terminase,capsid,lysis,tail,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000849212.1\|1648884_1649373_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_000686721.1\|1649778_1650273_+	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_000557378.1\|1650262_1650526_+	chaperone NapD	NA	NA	NA	NA
WP_000778055.1\|1650522_1653009_+	nitrate reductase catalytic subunit NapA	NA	NA	NA	NA
WP_000091291.1\|1653015_1653711_+	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_000013506.1\|1653697_1654561_+	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_000835177.1\|1654557_1655007_+	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_000528376.1\|1655016_1655619_+	cytochrome c-type protein NapC	NA	NA	NA	NA
WP_001328413.1\|1655637_1656255_+	cytochrome c biogenesis heme-transporting ATPase CcmA	G3M9Y6	Bacillus_virus	1.9e-12	25.5
WP_000971741.1\|1656251_1656914_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_001295447.1\|1656955_1657693_+	heme exporter protein CcmC	NA	NA	NA	NA
WP_000186534.1\|1657689_1657899_+	heme exporter protein CcmD	NA	NA	NA	NA
WP_001026418.1\|1657895_1658375_+	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_000982446.1\|1658371_1660315_+	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_000824439.1\|1660311_1660869_+	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_001211558.1\|1660865_1661918_+	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_001113637.1\|1661953_1662601_-	nitrate/nitrite response regulator protein NarP	NA	NA	NA	NA
WP_001551371.1\|1662920_1665512_+	autotransporter YejO	NA	NA	NA	NA
WP_001136067.1\|1666097_1666865_+	hypothetical protein	NA	NA	NA	NA
WP_001145023.1\|1666854_1667238_+	hypothetical protein	NA	NA	NA	NA
WP_106493932.1\|1667721_1668678_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_000741304.1\|1668815_1669994_-	recombinase	A0A2D1GN00	Marinobacter_phage	2.7e-31	30.6
WP_001096409.1\|1669996_1670206_-	hypothetical protein	NA	NA	NA	NA
WP_021548839.1\|1670267_1670483_-	hypothetical protein	K7PLX1	Enterobacteria_phage	3.7e-27	92.1
WP_001242718.1\|1670479_1670842_-	phage protein	K7PH61	Enterobacteria_phage	3.6e-67	99.2
WP_021548838.1\|1670832_1671369_-	5'-deoxynucleotidase	A0A0P0ZCH9	Stx2-converting_phage	5.3e-99	98.3
WP_000081280.1\|1671496_1672321_-	DUF2303 family protein	U5P439	Shigella_phage	6.0e-150	99.6
WP_000135680.1\|1672385_1672748_-	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_000141752.1\|1673185_1673431_+	hypothetical protein	NA	NA	NA	NA
WP_072018922.1\|1673348_1673624_-	hypothetical protein	Q8SBF7	Shigella_phage	5.9e-46	96.7
WP_000450737.1\|1674019_1674646_-	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	1.9e-47	48.8
WP_000205494.1\|1674743_1674944_+	cell division protein	NA	NA	NA	NA
WP_000515869.1\|1674981_1675539_+	protein YmfL	U5P4K1	Shigella_phage	8.8e-97	96.8
WP_001250269.1\|1675714_1675894_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_000104976.1\|1675883_1676825_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	3.9e-153	99.7
WP_074527436.1\|1676821_1677316_+	PerC family transcriptional regulator	A0A0P0ZCF0	Stx2-converting_phage	1.2e-86	98.8
WP_125316734.1\|1677315_1677897_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	5.7e-115	100.0
WP_000210155.1\|1677965_1678292_+	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	7.8e-53	98.1
WP_040074681.1\|1678288_1678678_+	RusA family crossover junction endodeoxyribonuclease	A0A291AX14	Escherichia_phage	4.6e-68	98.4
WP_087604717.1\|1678697_1679495_+	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	1.9e-148	98.9
WP_074527437.1\|1679502_1680492_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.3e-195	99.7
WP_044862710.1\|1680505_1681258_+	antitermination protein	Q8SBE4	Shigella_phage	9.9e-136	98.4
WP_000484663.1\|1681472_1682012_+	hypothetical protein	NA	NA	NA	NA
WP_001310393.1\|1682155_1682389_+	hypothetical protein	NA	NA	NA	NA
WP_096956487.1\|1682646_1683021_+	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	4.4e-60	93.5
WP_052978305.1\|1683088_1683304_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	2.0e-33	98.6
WP_000075159.1\|1683303_1683801_+	lysozyme	A5LH83	Enterobacteria_phage	1.3e-91	100.0
WP_001228685.1\|1684017_1684203_+	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	6.4e-20	80.3
WP_024174403.1\|1684286_1684610_+	protein KilA	A0A220NRM9	Escherichia_phage	7.9e-58	99.1
WP_024205918.1\|1684606_1684864_+	hypothetical protein	A0A0P0ZBT1	Stx2-converting_phage	1.1e-38	98.8
WP_000079508.1\|1685150_1685561_-	DUF1398 family protein	C6ZCX4	Enterobacteria_phage	1.3e-52	76.3
WP_000105084.1\|1685617_1685851_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.3e-21	94.4
WP_119785704.1\|1685866_1686124_-	hypothetical protein	A0A0K2FJC5	Escherichia_phage	8.9e-12	97.1
WP_000453587.1\|1686239_1686785_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_001027321.1\|1686759_1688685_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.4
WP_000198149.1\|1688681_1688888_+\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_057077926.1\|1688884_1690486_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	5.5e-309	98.9
WP_029395138.1\|1690466_1691786_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-232	98.4
WP_012304872.1\|1691795_1692128_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	4.6e-53	96.4
WP_029395141.1\|1692183_1693209_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	2.9e-186	96.8
WP_001468354.1\|1693250_1693646_+	DNA packaging FI family protein	A0A2R9YJP4	Escherichia_phage	3.1e-56	93.9
WP_029395143.1\|1693657_1694011_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	2.9e-61	98.3
WP_001518407.1\|1694022_1694601_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_021548556.1\|1694597_1694993_+\|tail	phage tail protein	A0A2R9YJI2	Escherichia_phage	5.0e-70	99.2
WP_021548555.1\|1695000_1695741_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	7.8e-125	94.3
WP_111530670.1\|1695756_1696179_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.2e-60	85.7
WP_000459458.1\|1696160_1696595_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	1.5e-64	99.2
WP_021548553.1\|1696587_1699167_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	86.7
WP_000847379.1\|1699163_1699493_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_001152640.1\|1699492_1700191_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.5e-133	99.6
WP_000194783.1\|1700196_1700940_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.2e-146	96.4
WP_000090895.1\|1700876_1701509_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	5.5e-95	89.5
WP_111530669.1\|1701569_1705067_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	98.2
WP_001233090.1\|1705137_1705737_+	Ail/Lom family protein	A5LH44	Enterobacteria_phage	8.2e-109	97.5
WP_150348808.1\|1705801_1709560_+	peptidase S74	A0A2D1UII2	Escherichia_phage	0.0e+00	88.6
WP_070749868.1\|1709614_1709743_+\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	7.3e-15	92.9
WP_001351450.1\|1710845_1712048_-	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_071701748.1\|1712238_1712331_+\|capsid	capsid protein	NA	NA	NA	NA

DBSCAN-SWA_3

1781589 : 1791032

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569343.1\|1781589_1782516_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	1.3e-23	30.8
WP_000783134.1\|1782520_1783252_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|1783232_1783340_-	protein YohO	NA	NA	NA	NA
WP_001240398.1\|1783399_1784131_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	2.8e-111	99.0
WP_001295431.1\|1784352_1786038_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_001308766.1\|1786034_1786754_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001551352.1\|1786800_1787271_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	5.2e-82	99.4
WP_032204114.1\|1787312_1787774_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	5.4e-76	99.3
WP_001551351.1\|1787898_1789899_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
WP_001551350.1\|1789895_1791032_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	5.0e-163	97.4

DBSCAN-SWA_4

1879296 : 1890211

Enterobacteria_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_125922846.1\|1879296_1880574_+	hypothetical protein	A0A1V0E6Q2	Klebsiella_phage	1.1e-12	24.5
WP_099147824.1\|1880609_1881938_+	flippase	NA	NA	NA	NA
WP_099147860.1\|1882017_1882410_+	serine acetyltransferase	A0A191KBJ5	Streptococcus_virus	6.8e-11	41.1
WP_000043542.1\|1882581_1883988_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	4.7e-38	28.7
WP_049139659.1\|1884212_1885277_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.4e-105	55.0
WP_016161468.1\|1885303_1886173_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	9.8e-111	66.7
WP_004206787.1\|1886204_1887095_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.7e-28	33.2
WP_004206788.1\|1887109_1887664_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	1.0e-52	58.8
WP_000704907.1\|1887844_1889011_+	UDP-glucose 6-dehydrogenase	M1I798	Paramecium_bursaria_Chlorella_virus	7.0e-112	54.7
WP_087523507.1\|1889203_1890211_+	NAD-dependent epimerase	E3T4Y8	Cafeteria_roenbergensis_virus	1.2e-30	28.6

DBSCAN-SWA_5

2816545 : 2875176

Escherichia_phage(42.55%)

head,integrase,terminase,holin,capsid,transposase,tRNA,tail,portal

attL 2824737:2824751|attR 2875278:2875292

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001297484.1\|2816545_2817652_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_001297479.1\|2817687_2818329_+	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000423742.1\|2818332_2819703_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.2e-107	44.9
WP_001265471.1\|2819871_2820543_+	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000735412.1\|2820542_2822003_+	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_000456506.1\|2822078_2823200_+	cupin domain-containing protein	NA	NA	NA	NA
WP_000359434.1\|2823248_2824475_-	peptidase T	NA	NA	NA	NA
WP_000531594.1\|2824724_2825861_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
2824737:2824751	attL	NA	NA	NA	NA
WP_000799406.1\|2825844_2826708_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000241001.1\|2827262_2827931_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_001309429.1\|2827875_2828013_-	hypothetical protein	NA	NA	NA	NA
WP_042047081.1\|2828168_2828699_-	chaperone of endosialidase	A0A2D1UII2	Escherichia_phage	2.5e-69	85.2
WP_032143699.1\|2829432_2829804_-	hypothetical protein	NA	NA	NA	NA
WP_001189123.1\|2830112_2831621_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.6e-44	31.8
WP_001233546.1\|2835574_2836174_-	Ail/Lom family outer membrane beta-barrel protein	H6WZM8	Escherichia_phage	1.6e-107	95.0
WP_000515345.1\|2836241_2839721_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	89.9
WP_000090843.1\|2839781_2840390_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.9e-100	94.1
WP_001333568.1\|2840326_2841070_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	4.5e-149	97.2
WP_001152457.1\|2841075_2841774_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	3.4e-130	97.0
WP_001330090.1\|2841773_2842130_-\|tail	tail protein	A0A0P0ZDL9	Stx2-converting_phage	2.8e-40	66.7
WP_000224003.1\|2842107_2845335_-\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	95.0
WP_077253127.1\|2845381_2845642_-	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	2.3e-39	95.3
WP_001324129.1\|2845683_2846070_-\|tail	tail assembly protein	A0A1B5FP91	Escherichia_phage	8.9e-64	100.0
WP_000097535.1\|2846069_2846774_-	hypothetical protein	A0A1B5FP82	Escherichia_phage	1.4e-112	92.7
WP_001206700.1\|2846834_2847179_-	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	5.1e-55	96.5
WP_000968644.1\|2847175_2847625_-	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	6.1e-64	81.2
WP_001147814.1\|2847621_2847960_-\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	7.5e-51	90.2
WP_000719064.1\|2847968_2848286_-\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	5.3e-22	49.5
WP_000766109.1\|2848362_2849580_-\|capsid	phage major capsid protein	A0A1W6JP20	Morganella_phage	5.9e-162	71.6
WP_000923134.1\|2850185_2851412_-\|portal	phage portal protein	Q8SBI0	Shigella_phage	3.7e-204	83.3
WP_001140892.1\|2851559_2853317_-\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	99.3
WP_001333563.1\|2853316_2853799_-\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	8.7e-85	98.1
WP_001135104.1\|2853946_2854297_-	HNH endonuclease	A0A1B5FP94	Escherichia_phage	8.0e-64	96.6
WP_071586179.1\|2854589_2854730_-	Rz1 lytic protein	U5P461	Shigella_phage	1.0e-09	84.6
WP_000738421.1\|2854822_2855116_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	5.9e-44	90.7
WP_075202333.1\|2855206_2855389_-	hypothetical protein	A0A0P0ZE50	Stx2-converting_phage	2.2e-17	77.0
WP_000992097.1\|2855605_2856139_-	lysozyme	Q08J98	Stx2-converting_phage	1.5e-98	93.2
WP_000193264.1\|2856202_2856553_-	YdfR family protein	K7PGU6	Enterobacteria_phage	1.4e-36	94.0
WP_000372595.1\|2856557_2856773_-\|holin	holin	A0A2R2Z340	Escherichia_phage	3.4e-33	98.6
WP_000874243.1\|2857080_2857269_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	7.2e-27	95.2
WP_001333560.1\|2857529_2857865_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	1.4e-44	74.8
WP_001333559.1\|2857935_2858148_+	hypothetical protein	NA	NA	NA	NA
WP_106104550.1\|2858636_2858723_-	DUF3927 family protein	NA	NA	NA	NA
WP_000762879.1\|2859117_2859939_-	antitermination protein	K7P7B9	Enterobacteria_phage	5.1e-77	58.2
WP_000139999.1\|2859935_2860316_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.6
WP_001221526.1\|2860316_2861375_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	7.5e-89	48.0
WP_032155008.1\|2861376_2861655_-	hypothetical protein	A0A077KB22	Edwardsiella_phage	6.1e-06	37.1
WP_001013636.1\|2861822_2862035_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	8.9e-26	96.9
WP_000786213.1\|2862237_2862417_-	hypothetical protein	NA	NA	NA	NA
WP_002431311.1\|2862988_2864530_+\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.3e-129	46.4
WP_001016257.1\|2864544_2865291_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
WP_001224662.1\|2865658_2865841_-	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
WP_000403785.1\|2865934_2866291_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.8e-58	99.2
WP_001151150.1\|2866348_2866771_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.6e-64	90.6
WP_001262390.1\|2866811_2867882_-	hypothetical protein	A0A088CD36	Shigella_phage	2.6e-52	56.6
WP_000693850.1\|2867953_2868379_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000747951.1\|2868362_2868605_-	hypothetical protein	H9C161	Pectobacterium_phage	4.8e-07	55.8
WP_001420344.1\|2868996_2869335_+	peptidase S24	H9C160	Pectobacterium_phage	2.5e-06	32.0
WP_001092153.1\|2869766_2869967_-	hypothetical protein	NA	NA	NA	NA
WP_001171946.1\|2870059_2870278_+	hypothetical protein	NA	NA	NA	NA
WP_001517906.1\|2870242_2870446_-	hypothetical protein	NA	NA	NA	NA
WP_000854558.1\|2870846_2871035_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001070255.1\|2871031_2871223_+	DUF1482 family protein	NA	NA	NA	NA
WP_000102136.1\|2871316_2873758_+	exonuclease	V5UQJ3	Shigella_phage	3.1e-114	46.9
WP_000003742.1\|2873819_2874089_+	excisionase	NA	NA	NA	NA
WP_000074971.1\|2874057_2875176_+\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	1.6e-84	44.4
2875278:2875292	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3761444 : 3814199

Morganella_phage(16.67%)

transposase,plate,integrase

attL 3766149:3766164|attR 3823631:3823646

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000230707.1\|3761444_3761900_+	hypothetical protein	A0A1W6JPI4	Morganella_phage	2.9e-45	66.4
WP_000678612.1\|3761979_3762180_+	hypothetical protein	H6WRV2	Salmonella_phage	1.3e-05	43.1
WP_050571080.1\|3762405_3762642_-	hypothetical protein	NA	NA	NA	NA
WP_016231257.1\|3762663_3763101_+	hypothetical protein	I6S5X4	Salmonella_phage	3.1e-12	33.1
WP_016231258.1\|3763163_3765269_-	hypothetical protein	A0A2I7QQN9	Vibrio_phage	1.4e-86	36.2
WP_016231259.1\|3765268_3766735_-	hypothetical protein	B6SCW4	Bacteriophage	1.4e-106	53.3
3766149:3766164	attL	NA	NA	NA	NA
WP_014639558.1\|3767179_3767431_-	hypothetical protein	NA	NA	NA	NA
WP_087523544.1\|3767497_3770254_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	2.6e-298	57.0
WP_001058739.1\|3770266_3770869_-	hypothetical protein	Q8W653	Enterobacteria_phage	5.3e-23	34.7
WP_000181940.1\|3770861_3771083_-	hypothetical protein	NA	NA	NA	NA
WP_001024673.1\|3771079_3771343_-	hypothetical protein	NA	NA	NA	NA
WP_001065738.1\|3771339_3771534_-	hypothetical protein	NA	NA	NA	NA
WP_077900594.1\|3771526_3772594_-	ash family protein	NA	NA	NA	NA
WP_033554327.1\|3772587_3772770_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_087523546.1\|3772762_3773572_-	antA/AntB antirepressor family protein	A0A0R6PJV6	Moraxella_phage	3.0e-29	53.6
WP_000412539.1\|3773584_3774016_-	hypothetical protein	A0A1W6JPH9	Morganella_phage	3.0e-28	49.7
WP_074525659.1\|3774015_3774219_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	4.7e-08	50.9
WP_074525658.1\|3774266_3774500_+	excinuclease ABC subunit B	NA	NA	NA	NA
WP_021531046.1\|3774611_3775826_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	7.5e-133	56.5
WP_000893278.1\|3776181_3777435_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	9.8e-96	47.2
WP_001285288.1\|3777446_3778550_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_039023169.1\|3778837_3779893_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	2.0e-118	60.9
WP_000174677.1\|3779931_3780333_-	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000189532.1\|3780390_3781635_-	esterase FrsA	NA	NA	NA	NA
WP_001291990.1\|3781726_3782185_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_001292994.1\|3782445_3783903_+	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_001326471.1\|3783959_3784496_-	peptide chain release factor H	NA	NA	NA	NA
WP_001295202.1\|3784428_3784695_-	hypothetical protein	NA	NA	NA	NA
WP_001059892.1\|3785000_3785453_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001263489.1\|3785462_3785861_-	type II toxin-antitoxin system mRNA interferase toxin YafO	NA	NA	NA	NA
WP_000554758.1\|3785863_3786157_-	type I toxin-antitoxin system antitoxin YafN	NA	NA	NA	NA
WP_001226164.1\|3786208_3787264_-	DNA polymerase IV	NA	NA	NA	NA
WP_001333407.1\|3787334_3788105_-	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001334802.1\|3788064_3789804_+	flagellar type III secretion system protein FlhA	NA	NA	NA	NA
WP_000006255.1\|3790027_3790525_-\|transposase	REP-associated tyrosine transposase RayT	NA	NA	NA	NA
WP_000056849.1\|3790700_3791450_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	9.0e-20	38.5
WP_000729703.1\|3791659_3791920_+	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
WP_000615983.1\|3791922_3792201_+	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
WP_001225679.1\|3792356_3793097_+	murein L,D-transpeptidase	NA	NA	NA	NA
WP_000333380.1\|3793067_3793835_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_000284050.1\|3794040_3794619_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_000973083.1\|3794858_3797303_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_000532698.1\|3797345_3797819_-	C-lysozyme inhibitor	NA	NA	NA	NA
WP_087523548.1\|3797972_3798743_+	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_000420818.1\|3798783_3799920_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_024198219.1\|3800510_3800744_-	hypothetical protein	NA	NA	NA	NA
WP_039023185.1\|3800721_3804954_-	RHS repeat protein	A0A2H4JHK7	uncultured_Caudovirales_phage	6.4e-22	43.1
WP_032329316.1\|3805029_3807171_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.4e-25	25.0
WP_001142958.1\|3807380_3807899_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000037397.1\|3808593_3809094_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000123970.1\|3809128_3809353_+	hypothetical protein	NA	NA	NA	NA
WP_000056989.1\|3809403_3810879_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000611744.1\|3810885_3811299_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000393852.1\|3811302_3813153_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000348793.1\|3813116_3814199_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
3823631:3823646	attR	NA	NA	NA	NA

DBSCAN-SWA_7

4547552 : 4626905

Escherichia_phage(40.0%)

integrase,protease,transposase,tRNA,tail

attL 4557252:4557287|attR 4635790:4635825

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000187022.1\|4547552_4548653_+\|tRNA	tRNA (uridine(54)-C5)-methyltransferase TrmA	NA	NA	NA	NA
WP_000806411.1\|4548692_4549052_-	YijD family membrane protein	NA	NA	NA	NA
WP_001309117.1\|4549051_4549702_-	HTH-type transcriptional repressor FabR	NA	NA	NA	NA
WP_001120810.1\|4550032_4551433_+	Si-specific NAD(P)(+) transhydrogenase	NA	NA	NA	NA
WP_001025939.1\|4551415_4552333_-	DNA-binding transcriptional regulator OxyR	NA	NA	NA	NA
WP_001230087.1\|4552599_4553973_-	argininosuccinate lyase	NA	NA	NA	NA
WP_001352356.1\|4554033_4554810_-	acetylglutamate kinase	NA	NA	NA	NA
WP_000935370.1\|4554817_4555822_-	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_001298964.1\|4555975_4557127_+	acetylornithine deacetylase	NA	NA	NA	NA
4557252:4557287	attL	NA	NA	NA	NA
WP_001005586.1\|4557724_4560376_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_000556306.1\|4560557_4562291_+	phosphoethanolamine transferase CptA	NA	NA	NA	NA
WP_000274643.1\|4562505_4563357_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000323841.1\|4563343_4563685_-	PTS fructose-like transporter subunit IIB	NA	NA	NA	NA
WP_000204105.1\|4563686_4564565_-	[formate-C-acetyltransferase]-activating enzyme	NA	NA	NA	NA
WP_000184811.1\|4564530_4566828_-	formate C-acetyltransferase	A0A1S6UAD4	Serratia_phage	4.6e-06	48.1
WP_000161265.1\|4566878_4567199_-	PTS fructose-like transporter subunit IIB	NA	NA	NA	NA
WP_001004446.1\|4567213_4568293_-	PTS fructose transporter subunit EIIC	NA	NA	NA	NA
WP_039023143.1\|4568601_4571103_+	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	7.9e-12	26.9
WP_000424840.1\|4571114_4571777_+	fructose-6-phosphate aldolase	A0A0E3F0E2	Synechococcus_phage	5.5e-29	34.6
WP_000374004.1\|4571787_4572891_+	bifunctional L-1,2-propanediol dehydrogenase/glycerol dehydrogenase	NA	NA	NA	NA
WP_000647894.1\|4573165_4573783_+	DUF1287 domain-containing protein	NA	NA	NA	NA
WP_001271242.1\|4573809_4574715_-	cystine transporter YijE	NA	NA	NA	NA
WP_001295695.1\|4574807_4576988_-	catalase/peroxidase HPI	NA	NA	NA	NA
WP_000007529.1\|4577316_4578207_-	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_000110772.1\|4578555_4580988_-	bifunctional aspartate kinase/homoserine dehydrogenase II	NA	NA	NA	NA
WP_001295694.1\|4580990_4582151_-	cystathionine gamma-synthase	NA	NA	NA	NA
WP_000852812.1\|4582427_4582745_+	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_000797353.1\|4582928_4583537_+	YiiX family permuted papain-like enzyme	NA	NA	NA	NA
WP_000710769.1\|4583597_4583810_-	50S ribosomal protein L31	NA	NA	NA	NA
WP_001333520.1\|4584012_4586211_+	primosomal protein N'	NA	NA	NA	NA
WP_000644904.1\|4586366_4587392_+	DNA-binding transcriptional regulator CytR	NA	NA	NA	NA
WP_000068828.1\|4587483_4588443_+	cell division protein FtsN	NA	NA	NA	NA
WP_000208242.1\|4588535_4589066_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_001293341.1\|4589075_4590407_+	HslU--HslV peptidase ATPase subunit	A0A191ZC11	Erwinia_phage	1.7e-45	29.9
WP_000139496.1\|4590473_4591400_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000872908.1\|4591492_4591978_+	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_001296623.1\|4592062_4592308_-	septal ring assembly protein ZapB	NA	NA	NA	NA
WP_000084268.1\|4592732_4593578_+	glycerol uptake facilitator protein GlpF	M1HWZ0	Paramecium_bursaria_Chlorella_virus	4.4e-15	28.0
WP_000136788.1\|4593600_4595109_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_001250644.1\|4595243_4596254_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000796332.1\|4596350_4597097_+	ferredoxin--NADP(+) reductase	NA	NA	NA	NA
WP_000323547.1\|4597101_4597530_-	universal stress protein UspD	NA	NA	NA	NA
WP_000655989.1\|4597556_4597856_-	DUF406 domain-containing protein	NA	NA	NA	NA
WP_000155257.1\|4598067_4598508_-	DUF805 domain-containing protein	NA	NA	NA	NA
WP_000802214.1\|4598608_4599208_+	YiiQ family protein	NA	NA	NA	NA
WP_001216327.1\|4599315_4600083_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_001326656.1\|4600137_4600893_-	CDP-diacylglycerol diphosphatase	NA	NA	NA	NA
WP_001045683.1\|4600999_4601989_-	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000591795.1\|4602308_4603271_-	6-phosphofructokinase	NA	NA	NA	NA
WP_001076742.1\|4603451_4604354_-	CDF family cation-efflux transporter FieF	NA	NA	NA	NA
WP_001145759.1\|4604561_4605074_-	hypothetical protein	NA	NA	NA	NA
WP_085947770.1\|4605347_4606717_-\|transposase	IS3-like element IS150 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.3e-112	100.0
WP_000468308.1\|4606789_4607008_-	prophage transcriptional regulator OgrK	A0A0F7LDQ9	Escherichia_phage	4.7e-38	100.0
WP_000882940.1\|4607089_4608253_-	phage late control D family protein	U5N3V4	Enterobacteria_phage	4.8e-206	99.5
WP_000978889.1\|4608252_4608732_-\|tail	phage tail protein	A0A0F7LDE8	Escherichia_phage	1.5e-84	99.4
WP_000069960.1\|4608746_4611194_-\|tail	phage tail tape measure protein	M1T2S3	Escherichia_phage	0.0e+00	95.2
WP_000785970.1\|4611186_4611306_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
WP_001031307.1\|4611338_4611614_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	2.2e-40	98.9
WP_001251408.1\|4611670_4612189_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
WP_001286718.1\|4612201_4613392_-\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	3.7e-225	99.7
WP_062914736.1\|4613451_4614054_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	3.5e-99	95.3
WP_001333339.1\|4614061_4615597_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.5e-289	99.4
WP_000612626.1\|4615645_4615993_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839179.1\|4615989_4616394_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_001016257.1\|4616714_4617461_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
WP_002431311.1\|4617475_4619017_-\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.3e-129	46.4
WP_000027659.1\|4620491_4620767_-	DUF5405 family protein	A0A0F7LCM4	Escherichia_phage	2.3e-45	100.0
WP_001113270.1\|4620763_4620988_-	TraR/DksA family transcriptional regulator	A0A0F7LDI3	Escherichia_phage	3.8e-35	98.6
WP_001277952.1\|4620987_4621290_-	DUF5405 family protein	A0A0F7LDT6	Escherichia_phage	2.5e-45	96.0
WP_000557703.1\|4621289_4621514_-	DUF2732 family protein	S4TP68	Salmonella_phage	4.7e-33	100.0
WP_000217670.1\|4621577_4622078_-	hypothetical protein	M1SV55	Escherichia_phage	2.6e-92	100.0
WP_001308179.1\|4622247_4622520_-	hypothetical protein	Q1JS36	Enterobacteria_phage	1.4e-47	100.0
WP_000777029.1\|4622656_4622950_+	helix-turn-helix domain-containing protein	Q1JS37	Enterobacteria_phage	2.7e-49	100.0
WP_000985246.1\|4623019_4624000_+\|integrase	tyrosine-type recombinase/integrase	S4TP66	Salmonella_phage	4.7e-186	100.0
WP_001223800.1\|4624186_4624687_-	cell-envelope stress modulator CpxP	NA	NA	NA	NA
WP_001033722.1\|4624836_4625535_+	envelope stress response regulator transcription factor CpxR	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
WP_000580417.1\|4625531_4626905_+	envelope stress sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	3.8e-16	25.9
4635790:4635825	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP043943

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13920 : 33306

Escherichia_phage(33.33%)

integrase,transposase

attL 8977:8991|attR 35656:35670

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
8977:8991	attL	NA	NA	NA	NA
WP_001067858.1\|13920_14625_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_001043260.1\|14840_15656_+	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_000251875.1\|15742_16045_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001445143.1\|15938_16190_-	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|16220_17714_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_001255015.1\|17825_18131_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_039026029.1\|18158_19373_-	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	3.2e-19	29.1
WP_001447541.1\|19589_20474_-	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_021561477.1\|23336_24197_-	inhibitor-resistant class A broad-spectrum beta-lactamase TEM-30	Q1MVP3	Enterobacteria_phage	3.9e-160	99.7
WP_001067858.1\|24318_25023_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000679427.1\|25878_26226_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001206317.1\|26389_27181_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA1	NA	NA	NA	NA
WP_000777555.1\|27273_27747_-	trimethoprim-resistant dihydrofolate reductase DfrA1	G3MBI7	Bacillus_virus	3.7e-19	32.1
WP_000845048.1\|27903_28917_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001067858.1\|29613_30318_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_001596999.1\|30351_30609_-	hypothetical protein	NA	NA	NA	NA
WP_001290416.1\|30653_31580_-	hypothetical protein	NA	NA	NA	NA
WP_000465036.1\|32111_32525_+	hypothetical protein	NA	NA	NA	NA
WP_001164198.1\|32526_33306_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.0e-55	95.6
35656:35670	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP043944

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP043942

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP043943

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection