CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP023688	Streptomyces rimosus strain ATCC 10970 chromosome, complete genome	10 crisprs	csa3,RT,cas8e,DEDDh,DinG,WYL,cas3,cas4,casR	0	3	6	0

1. NZ_CP023688

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP023688_1

• CRISPR_ID: NZ_CP023688_1
• CRISPR_location: 984678-984860
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP023688_1

Consensus_repeat	Method
ACTGGGGGTACACCGGAGCGATCGACGG	CRISPRCasFinder

spacers of NZ_CP023688_1

>1.1|984706|49|NZ_CP023688|CRISPRCasFinder
CCGGCTGGGACGGGCAGCTGGAAGGCGTTCCAGCGCTGCCTCAAGGCGA
>1.2|984783|50|NZ_CP023688|CRISPRCasFinder
GAAGGTCGGGTCCGGCACCGTCAAGACGCTGCAGCGTCTGCTGAAGCACA

CRISPR arrays and Neighbor proteins around NZ_CP023688_1

CRISPR arrays

The CRISPR arrays of NZ_CP023688_1

>merge|NZ_CP023688|1|984678-984860|CRISPRCasFinder
ACTGGGGGTACACCGGAGCGATCGACGGCCGGCTGGGACGGGCAGCTGGAAGGCGTTCCAGCGCTGCCTCAAGGCGAACTGGGGCTACACCGGAGCGATCGACGGGAAGGTCGGGTCCGGCACCGTCAAGACGCTGCAGCGTCTGCTGAAGCACAGCTGGGGCTACACCGGCCAGATCGACGG

>NZ_CP023688|1|1|984678-984860|CRISPRCasFinder
ACTGGGGGTACACCGGAGCGATCGACGG	CCGGCTGGGACGGGCAGCTGGAAGGCGTTCCAGCGCTGCCTCAAGGCGA
ACTGGGGCTACACCGGAGCGATCGACGG	GAAGGTCGGGTCCGGCACCGTCAAGACGCTGCAGCGTCTGCTGAAGCACA
GCTGGGGCTACACCGGCCAGATCGACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_003984599.1|981978_983454_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP023688.1|WP_030182010.1|991334_991781_+|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|274679
NZ_CP023688.1|WP_030182016.1|978400_979216_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP023688.1|WP_063785074.1|997057_1000378_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|274846
NZ_CP023688.1|WP_030182015.1|979506_980583_+|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|237408
NZ_CP023688.1|WP_129821017.1|973945_975160_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NZ_CP023688.1|WP_003984603.1|976807_978373_+|AMP-binding-protein	unknown	unknown	gnl|CDD|235731
NZ_CP023688.1|WP_003984594.1|986294_986924_+|RraA-family-protein	unknown	unknown	gnl|CDD|319245
NZ_CP023688.1|WP_003984598.1|983533_984097_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP023688.1|WP_003984605.1|975364_975811_+|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|237999
NZ_CP023688.1|WP_003984608.1|973257_974067_-|efflux-protein	unknown	unknown	gnl|CDD|240536
NZ_CP023688.1|WP_050504593.1|988922_990500_-|adenylosuccinate-synthetase	unknown	unknown	gnl|CDD|376374
NZ_CP023688.1|WP_094777479.1|993354_995172_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187546
NZ_CP023688.1|WP_078586977.1|1000491_1003359_+|M4-family-metallopeptidase	unknown	unknown	gnl|CDD|341060
NZ_CP023688.1|WP_003984593.1|986913_988191_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP023688.1|WP_003984600.1|980889_981834_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|375319
NZ_CP023688.1|WP_003984592.1|988290_988926_-|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl|CDD|129813
NZ_CP023688.1|WP_003984309.1|996068_996338_-|hypothetical-protein	unknown	unknown	gnl|CDD|180828
NZ_CP023688.1|WP_003984595.1|985156_986116_-|D-2-hydroxyacid-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|240646
NZ_CP023688.1|WP_003984604.1|975954_976629_+|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341362

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_003984599.1|981978_983454_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.51153e-59
NZ_CP023688.1|WP_030182010.1|991334_991781_+|pyridoxamine-5'-phosphate-oxidase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	7.94286e-17
NZ_CP023688.1|WP_030182016.1|978400_979216_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.32482e-28
NZ_CP023688.1|WP_063785074.1|997057_1000378_+|AAA-family-ATPase	gnl|CDD|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	1.33725e-40
NZ_CP023688.1|WP_030182015.1|979506_980583_+|glutamate--cysteine-ligase	gnl|CDD|237408	PRK13517, PRK13517, glutamate--cysteine ligase.	4.20884e-146
NZ_CP023688.1|WP_129821017.1|973945_975160_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	1.58231e-102
NZ_CP023688.1|WP_003984603.1|976807_978373_+|AMP-binding-protein	gnl|CDD|235731	PRK06188, PRK06188, acyl-CoA synthetase; Validated.	1.53166e-149
NZ_CP023688.1|WP_003984594.1|986294_986924_+|RraA-family-protein	gnl|CDD|319245	cd16841, RraA_family, ribonuclease activity regulator RraA family. RraA protein family is named after the regulator of ribonuclease activity A (RraA), a protein that binds to RNase E and inhibits RNase E endonucleolytic cleavages. Members also include proteins with other functions, like a 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate (HMG/CHA) aldolase from Pseudomonas putida, which catalyzes the last step of the bacterial protocatechuate 4,5-cleavage pathway and the uncharacterized YER010Cp protein from yeast, an organism lacking RNAse E.	5.5325e-52
NZ_CP023688.1|WP_003984598.1|983533_984097_+|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	2.37103e-22
NZ_CP023688.1|WP_003984605.1|975364_975811_+|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	1.08431e-20
NZ_CP023688.1|WP_003984608.1|973257_974067_-|efflux-protein	gnl|CDD|240536	cd13131, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.	4.2092e-54
NZ_CP023688.1|WP_050504593.1|988922_990500_-|adenylosuccinate-synthetase	gnl|CDD|376374	pfam00709, Adenylsucc_synt, Adenylosuccinate synthetase.	3.99974e-158
NZ_CP023688.1|WP_094777479.1|993354_995172_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187546	cd05235, SDR_e1, extended (e) SDRs, subgroup 1. This family consists of an SDR module of multidomain proteins identified as putative polyketide sythases fatty acid synthases (FAS), and nonribosomal peptide synthases, among others. However, unlike the usual ketoreductase modules of FAS and polyketide synthase, these domains are related to the extended SDRs, and have canonical NAD(P)-binding motifs and an active site tetrad. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.79283e-91
NZ_CP023688.1|WP_078586977.1|1000491_1003359_+|M4-family-metallopeptidase	gnl|CDD|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	5.71439e-77
NZ_CP023688.1|WP_003984593.1|986913_988191_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.39163e-42
NZ_CP023688.1|WP_003984600.1|980889_981834_-|helix-turn-helix-domain-containing-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	1.62153e-48
NZ_CP023688.1|WP_003984592.1|988290_988926_-|TIGR00730-family-Rossman-fold-protein	gnl|CDD|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	5.19788e-52
NZ_CP023688.1|WP_003984309.1|996068_996338_-|hypothetical-protein	gnl|CDD|180828	PRK07081, PRK07081, acyl carrier protein; Provisional.	0.00383605
NZ_CP023688.1|WP_003984595.1|985156_986116_-|D-2-hydroxyacid-dehydrogenase-family-protein	gnl|CDD|240646	cd12169, PGDH_like_1, Putative D-3-Phosphoglycerate Dehydrogenases. Phosphoglycerate dehydrogenases (PGDHs) catalyze the initial step in the biosynthesis of L-serine from D-3-phosphoglycerate. PGDHs come in 3 distinct structural forms, with this first group being related to 2-hydroxy acid dehydrogenases, sharing structural similarity to formate and glycerate dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily, which also include groups such as L-alanine dehydrogenase and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. Many, not all, members of this family are dimeric.	2.60505e-169
NZ_CP023688.1|WP_003984604.1|975954_976629_+|CBS-domain-containing-protein	gnl|CDD|341362	cd04586, CBS_pair_BON_assoc, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection proteins. It is also found in some secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	9.02291e-42

Protein sequences

>NZ_CP023688.1|WP_003984598.1|983533_984097_+|GNAT-family-N-acetyltransferase
MFAISLGDDGAVLCPLEPWQAEELLAHIDRGREFIGQYNGLPEVLGDLDACRAFLRTYAEKVASDTGHLYGIRTDGTLVGAVFFRTMDIAQGTAEVGCWLEPAAAGKGLVTRAVRVLIDWAVEVRGIHRVEWWAAAENLPSIAVARRLGMTRDGVARQSYPYRGKRHDMEIWSVLAPEWRAQRSADR
>NZ_CP023688.1|WP_003984599.1|981978_983454_+|MFS-transporter
MTYTRPPADSGYDVLRADADRAHAAPSPWRALSVVLIGIFVAVLDTFIVLVATPAIQRDLHASDADVQLVLAGYQLAYAVALITGARLGDLFGRKRCFLIGMALFTLASVACAAAPGAGALIGARLVQGLGAAVMSPQVFSTIQVLLPPERRARAFGVLGAVIGTAGVAGQLLGGVLVSADLFGTSWRPIFWVNVPVGLLTLALAAVLVPESRAPEARRLDLAGAAVLTPALFLLVVPLVEGREAGWPLWTWLSLALGALALVAFARVERRVEARGGSPLVRLRLLRSRAFAVGMVLVLLTYFGINSFFLVLSVTLQDGLGLGTLAAGAFYLPFAAAFFAGSLAAGRLARYGRRLLQAGALVLGLGHAAAIAVVLQAGAALTAWHLAVPLLVIGAGTGVLVTPLLNAVLARVRPAEIGMASGILSTSQQVGGSVGVAAIGVIFYGTLGDATHHDPAAYGPALAAALAFCLALAVAVSVLLRALPQPPGAGQ
>NZ_CP023688.1|WP_003984600.1|980889_981834_-|helix-turn-helix-domain-containing-protein
MSRREAGTDGRREAVPSGAGTASGPERRRVLAAFLRSRRERIAPGDAGLPAGPRRRTPGLRREEVATLSGVSVTWYTWLEQARDITVSRQVLHSLARVLYLSPAETRHLFALAGQPLPAPDAVRAGGRPLQRLVDALDPHPAYVVAANWDLLAWNRAEAGLIGDPAHWDDPERNLLRLVFTDPRIRTLLADWPDQARTLLEQYRASADRHTGDPAFTRLTAELRERSEEFRTWWDTHDIAEFRPTRRVFDHPHLGRLTFDYVKLTPVDTPGVTLVSCLPSDDGTAGKLGALSECAAGDRGVTSEPGAEGALNPE
>NZ_CP023688.1|WP_030182015.1|979506_980583_+|glutamate--cysteine-ligase
MRSVGVEEELLLVDPYSGEPRAVAGTVLASTPHDSTLDKELHREQLEIATRPRTLIEDLAEEVGRWRGEAAHRARRAGTELAALATSPLPVTPSLSVDERYQRLEEEFGRTAQEQLACGCHIHVAVESDDEGVAVLDRIRPWLPTLLALSANSPFWQGKDTRYSSYRSRVWGRWPSSGPMEPFGSAENYHRRVQEMLATGTLLDEGMIYFDARLSRHYPTVEIRVADVCLQSDDTVLLAALTRGLVETAARAWRAGEPPDSAGIGLLRLATWRAGRSGLSGRLVHPLTWTPAPAEAVVRALLDHVSEALEDIGDLALAKEGLDTLMGRGNGAQVQRELLARTGDLRSVVGECVRRTAA
>NZ_CP023688.1|WP_030182016.1|978400_979216_-|alpha/beta-hydrolase
MPVLRTNGMRLAYQEYGSGEPVVMVTGTGAPGRVWRAHQVPALTAAGYRVITFDHRGVAPNGHPERPFTLDDMAADLAALIAHVSPGPCRVVGFSLGSIVVQELLVARPGLVGQAVLMATIGRADTLVGVMASAEIALCDSGAVLPPRYAAYVQALQYLSGETLADEERLRGWLDIFEMTAATDFTGVRGQLGLQVIRDRRPAYRAIRCPCLVIGFGDDRIVRPQLVREVAECIPGAAYTELAGCGHYGYLEKPELVNSAIVEFFAGWRKV
>NZ_CP023688.1|WP_003984603.1|976807_978373_+|AMP-binding-protein
MTTEADIAAVKVNSPTTAFRTYVESILHVLSAAPDRPVVTTADGRQVTAGEFRDDVYRIARELRGWGIGRGSTVSLLSGNRPEALTARYAANLLGARAVFLYQGMAPETLAHIARSVDTALLLVDPELPEATESLLAHARPPYVLSFGPGAHGQDLLARAARHEPRPVRSAARAEDDWCIRHTGGTTGVPKGVRMPHGPYEAMLAFGSLGAGEPPRFLACTTLAHVAGNIADATLLAGGSVVLQESFDPGRVLAAVERERISHLWLLPPLIYRLLDHPALVGTDLSSVRRISYGGCAASPTRLRQAHETFGAVLFGGYGQSEAGHVTVIGPDEHAKMPADGQATVGRVIPGVEVAIHDEHGAPVPVGAVGEIRVRSGQAMTGYWKQPELTAQVLRDGWMHTGDLGHLDHEGYLYIVDRLKDMIIVVGGHVYTSELEDLLLTHPDIAHCAAFGVRGPDAGEEVHIAVVPVPERPLDLDQVREYVTRHKGAMYAPSGMHLVTEIPLTPVGKPDKKRIREMLDE
>NZ_CP023688.1|WP_003984604.1|975954_976629_+|CBS-domain-containing-protein
MQEPETQGNSLRTVGDVMTRTVISIGRAAPFKEIVRTMEQWKVSALPVVEGEGRVVGVVSEADLLPKEEFRDHTPSRIEQLRVLDALIKSGGVTADELMTAPAVTVHADATLAQAARTMAWYRIKRMPVVDAVGRLEGVVSRSDLLKVFLREDEDIAEEVRRTVVGQLFTHRVHDLTVEVSEGIVTLSGTLADTSLIPVAARLARAVEGVVEVDIRLRGGPERP
>NZ_CP023688.1|WP_003984605.1|975364_975811_+|cyclic-nucleotide-binding-domain-containing-protein
MTGRLGALPAEHRERLMARAREVSFPAGVRIFEEDRRADRFWIVRTGAVQLDIRVPGRRAAVVETLHPGDPLGWSWLFPPYSWQLGAETLSPVRAWEFDAQEVRALCQEDPVLGHALVLMYAEVIGDRLRCARTRLLDLYGPYGSGVR
>NZ_CP023688.1|WP_129821017.1|973945_975160_+|ABC-transporter-ATP-binding-protein
MFRLSSGASTVSRLAEAYSARKERRYTSVVATPTKAVERLMADCHLPASLAHHRPGALSGGQQRRLALARALARRPEVLLLDEPTAGLDAALRDEITALLRRLATEHGLAVVMASHDPDVVEKCADMVVALATGDAPYAPYVPGAPYVPGAPSAPRSRPPNAPITLPEGLRAENLHVAFSHRGHTHQALAGADFHAPTGSATGITGPSGCGKTTLLRTLAGLQAPQSGTLTWDGRPLPAPVRKRSRDMQRRIQFVPQNPLGALNPARTIGATLARPLRLHRIVGVREMPARVGGLLDAVGLPGDFAHRYPHELSGGQRQRASIARALATEPDLLLCDEVTSALDPATATAVLDLLAHLRATRQLTLVLVSHETDLIGGYTDTVHLLRGGRVVRPAAPCEDAASA
>NZ_CP023688.1|WP_003984608.1|973257_974067_-|efflux-protein
MSRSTAFVGVATTLVYLLSFLALYASAKRDTVLAPLLSLNIARTDRATVRRLVRLGVPIAATYGSEAGFFSVTALMAGSFGSAALAAHTAVNQLVYIVFQVAVGLSHAASINVSRELALGRTGTALRIRNTALACAGAVMAVVAVVYATLPGLVLSPFFDTAAPRDAEAVSIATRLLLVVMVLQFFDCAQNIGVGLLRGLDDTSGGFRITLVGYWAVGLPAAWLLGYAAGLHTLGIWLGLLTGLATTAVLLLRRYGASLRARTPAPQTV
>NZ_CP023688.1|WP_003984595.1|985156_986116_-|D-2-hydroxyacid-dehydrogenase-family-protein
MHLRCAVLDDYQDIATTVADWSSVQDRVEVTGFTRHFATGDELAEALAGFDIVVTLRERVPFPAELFARLPRLKLLVASGMRNSVIDFAAAAEHGVTVCGTASSSTPPVELTWALLLGLARGVVTEHNALRAGGPWQSTVGADLHGKRLGLLGLGKIGSRVAQVGAAFGMDVVAWSQNLTEERTDEVGTGLAANLEELLRTSDFVSVHLALSDRTRGLLGAPELALLKPTAYLVNTSRAAIVDQDALLAALHEGRIAGAGIDVFDTEPLPAGHPMRTAPRLLATPHLGYVSRDNYRTYYGQAVEDIEAFLQGAPIRRLG
>NZ_CP023688.1|WP_003984594.1|986294_986924_+|RraA-family-protein
MNDFSGFRSIPTTTLADLLGRTQVMDVGIRPLWSPVPRVAGPAFTVRCPPGDNLMLHAAVHRAEPGAVIVVESGDMDYALAGGNVCAVARRRGVAAIVADGLIRDLGEVREAGFPVFARGVIPVPGSKAAVAPLNDPVRCGGVTVRAGDIVVADEEGVVVTPGPGDRQEQVLADARKKLAKEADETLDAWEAAHRARIDTILRDQGFTE
>NZ_CP023688.1|WP_003984593.1|986913_988191_-|cytochrome-P450
MPDAGRLPRYPFAFRGDQLAPELAASVVHRPIQRVRTNTGTDAWLVTGHELVRSVLRDRRFSLTLTSDPWMPRQDPLIPPLSVTDIRTQCENAGLLQDLFQGVGPHQRYLTPGRVREIADGLLDTFLAGEQPGDLMDGFIMPLSRALTMELLGLDPEGCPDNAEIFNIFRTGPESMQGVPESWNLALTWMLGRLPGLRASGAGLLGRLITLSDASGVLSEEEVADLFVFLLISQFGNPATFLGAATVGLMQHPEVTARLRKDPGLLPRAVDELLRWTVFLGDALPRNAREDVLLDGVLVREGDLVLVSTDAANRDPRVFPDPHRLDIDREPGPHLRFSDGRHRCPGGPVSRMQAAETLRVLLGRTADLRLAVPADEIEWHRYYAVTLPVAVPVNWTLPGAATPGTGDGKPRGAAVPRPDGGTLTP
>NZ_CP023688.1|WP_003984592.1|988290_988926_-|TIGR00730-family-Rossman-fold-protein
MNPNRHTGFTGDAADGTLKSLCVFCGASAGVRPTHVQLAARLGQTCARRGIRVVYGAGGVGVMGALSDAVLAEGGSITGVIPQALMDREYGRRDLTELRIVGSMHERKALMHSLSDAFLALPGGYGTLEELFEITAWAQLGLHHKRIVLLDDGGFFSPLGRMLDHARDEGFLSDADRQLVQHAKSVDDALRLAARPPAPPTEAPMIGPSQT
>NZ_CP023688.1|WP_050504593.1|988922_990500_-|adenylosuccinate-synthetase
MPDPDPARAQETTVPGPSPVVPPARPPDAPRDRVPPCDPRALWPALGASRQARRSALLAPLTRTSGPPPEQQHLTWVGDLQQGDGGKGAMTDRLAPAHQIAARVQGGDNAGHTTVFQGAEGGEHTLKNHLLPSGLRHPGVLGVIANGVLVNPQTLAEEIASFAPHVPALRRRLVISDRAHLVLPLHRLVDGRQESGGGRCSDVIGTTRRGIGPANVSKANRIGIRVRDLRDPDLLRRRIEQNVRFFGLPSGHADSDLKWLETYRDLLLSLAADTVALLGAAVEAGYSVLLEGAQGPVLDVEHGTYPYVTTSPTAFYSVTSGTGLDGSLVGHRVGVLKAYQTMVGNGPFVTEDAGELGDRLRRSGEEFGTTTGRSRRCGWLDLAHARWAAGFNRYTSVVVTKLDILDGFDRIGVCVGYQLPNGEYGEFVPDHEYLERCRPLYCWLPGWRHRTRGLTRYDQLPPEARSFLRYIADFLGVEVAAAGTGPADRDLLVDPAARLAGLLPAPAAAGLLRAVRNGREKRTMP
>NZ_CP023688.1|WP_030182010.1|991334_991781_+|pyridoxamine-5'-phosphate-oxidase
MSLAMNTADREAFLAGAHVAVLGIGAPDGPPLLVPVWYAYRPGGEIVVLTGRKSVKARRIRAAGRLGLCVQRETAPYKYVSVEGPVTAFEDRVDAAERAALAHRYLPPETARAYLAATADQLTTDVTVRMRPERWRTADFASFATAFS
>NZ_CP023688.1|WP_094777479.1|993354_995172_+|NAD-dependent-epimerase/dehydratase-family-protein
MRAYVASWLPAPAVPARIHVLDRFPVTSAGKVDRRALLARTTVPAARGGARPDAAVRAGSGPTGTGPGADGSTGQTDATGNGDANANGQRRARAARSGAGGGATGDGSGLLGVLADVWEHILRVRPTPADSFFDLGGDSLLIAEVTTRTMTALGMDAAHGTFLVRSLLREPTLGAYTAAVVRALRADRAGRRTGSAPASEADFLREARLGLRLPPVGGPVPRWRDPARVLVTGATGFVGAFLIDRLAHATGAELLCPVRARDAAHARRRVCSNAARYGLDTEPYEQRLTCFPADLAAPRLGLSEERFARLGETADLILHAGARVNFLYPYAALRPANVDGTRELVRLAAGRRIPLHFLSTIAVLAGFGTAGVRRVAEDAPLAHADHLTMGYAESKWVAERMLKDAARAGLPVAVHRPYEVTGEERTGICNTETAISSLFRVIAETGVAPDVPLPLDFVPVDHLAAAVVHLATHEPADGRTYHLTNPRPARLADMLARMRAAGYRIRELPYDAWVAELVRHVARHPSSPTTPFVSLCVDRSNKSDISVKEMYLDDVFPRLGRANTERGLAGSGLRCPPTDAALLDRYLAFFRSSGFLPPPLPRDGA
>NZ_CP023688.1|WP_003984309.1|996068_996338_-|hypothetical-protein
MNRTQKIQQFIEERFLVQFGGEVTADTDLFQAGVIDSFGYIQLMSFIENDFAVRDTDDELLSNIFVSLTDIDAFVAGLAEKRAPAGDGW
>NZ_CP023688.1|WP_063785074.1|997057_1000378_+|AAA-family-ATPase
MSARLDGADLPLGPPRRRALLALLLIRLGRVVPTELLIEELWQEDPPRHPVATLQSHLSHLRRVLAPAAGQGASSVLRYQAPGYVLQLAPEQVDAYRFEQMVTEGRQSLDRRDPRGARDRLTEALELWQGSPYTEFGARPPLSDETARLEQVRLSALEAGAEARLTLGAFEEVAAELGLEVRHHPTRERLVGHLMTALSRLGRQAEALEVYERTRSHLVEEFGVDTAAELQRVHTAILRQELDDCGPVSGAALAAPPATPQTAPAQAGQPPRVQEVVAPPVQVTGAEPADRDTAVTGPARRTRAAGSRRVRGADRDAPVRAASLPDDGQGAEDTSAPWPFIGRDQELHRLVIAAASAATGEGHVACVLGPAGVGKTRLLMELAPALEGGGDAPEVVWSHCFPGEGVPPYWLWTQVLRRLSSTRPDAFRSATAPFGALLAPLMPEQSAGSGGQDHDDDWAQARFLTHDAVCEVLLTLAAERPLVLLLEDLHWADAASLDLLRLLGTRRQGQRISIVLTARDPEGDSDAGIRRMLAEVLRSPRTESLRLGGLPRSAVAALVEARAGYGVGDDVIEVLHERSKGNPYFVMQLLSLLGDVRRLHDADATDVLLAQIPTGVREALRQRFAGLPEPALRVLRLCAVIGTEIDTDLLHRTAAEDEPVAPALETAIRAGLLGEDPHHPGRLHFVHALVRETLVDVLARNERQQLHARVAGALCERGGQVGDDEYERLAHHTWHAQDALPARRALPRLLRAAEQAEQQLAYEKVETWLRRAVHLAGLLPRDDASARSLEQRLYVQLGQLLATVRGYGDAEAEAALSRGRALGAVTHAPEDPSVLWALCAAFLVTGRYDESGRFSRLLRDIGSRTRHPVAQLGAAYGKGVALHVRGRLPEALAELERSVGLADRFAREGRSLARTFQHDPRVSCRSYDAFTHWILGDRDTALGRRCQLQALTAYESRPSDRCFALYVDAVLAAWEGDPDTARASGAEGARVAEEHGLLYWKAMLRLTEGWSLTHLGQDEAGLGLMHTSIAELRPSRSHLRLPLHLGLLAQAQHHAGRRDDATATLRKMLAVIEHRRELVYLHPALPATTLLHDLLGRHVTETILSS
>NZ_CP023688.1|WP_078586977.1|1000491_1003359_+|M4-family-metallopeptidase
MWQQAEGVTLRERRARGGRARVERPGGPGGLFGPRAAAGARGSLTGAAALVGVAALLASAVPAGAAPAGPPPGPGQVVPGQRTATPALVEGIREPAKATGSPAEAARGHLAAKESRYHIADPARDLRPVQTVDSGTHEVVRLQQKHRGVDVLGGQYVVRMEHKGGERVVTGTSGKYFTGLKTDVEPEVDEALAVERAVDATTERLLNKRLPRTDTPTLTGTARGLVVIPRGAGVLTRHITVRGTHPVTGEPVLHEVYVDAQAGYPVLQYSGIKTFRAPGGATAAGAPKAARTAAGVKGIQGSGVKYDGKTVELPVVYEESRKAYVLRDETRMANTSKNTLSTWDARGKDVSEVTPSWPYDIQEFGSPTPAFGPEATEAGAVDAHWASGKVYDYYRQQHGRDSLDGRGMAVNSLVGVTQFGQPYINAFWDGSKMVYGAGDAEYRTLSAGLDVVGHEMTHGVVENSANLVYAGQSGALNEGIADYFGNAIENDTYGIPMDSPDSGLLGETLCRTKPARECAIRDLNDGRTTAKSFLGVSFSEDNGGVHLNSTIFAGALWDLREDLGKTLADKIVYKALTEYLTPLDGFTEGRAAVLAAARDLHATDTQIRTAERAFNAHGIVPGWELAMGVDSDPLLGRVNTDGSATGAGGGWWAAAKSNDDGTEPYSIWAGRADGTGALKLMSPNDGRYHVHPATDGKTVVWQAYNRRSTDILARPIAGGPIKKLWSGRRGAVNVRVEGDVVVFEAQSRPSARKVRYVRLSDPTVVNVTDESGVRTGNPSISHGRIAYSTVRGIGNSRTYGVETLDLKTGQRTQMGQLGTPADISATAITGQHVFWLVPAGGESDRAALRRANLDGTGVTDLSPAEGPDALNGYDIVATDEAVTVATWSPTVVYTNESLFKLWQFSADGKQRGRVSCNRGQQGWPAMPGGRQVVWVDGTTGYTDLVTRTRPAGRCG

Crispr_ID: NZ_CP023688_2

• CRISPR_ID: NZ_CP023688_2
• CRISPR_location: 1720204-1720352
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP023688_2

Consensus_repeat	Method
GGCCGACGGGACCCACAGATCCGCCGTCCCCGGTCAGCCCCGCCGCTCGCC	CRISPRCasFinder

spacers of NZ_CP023688_2

>2.1|1720255|47|NZ_CP023688|CRISPRCasFinder
ACACGCACCACCACGCAGGCCACCGAAAACGGCCCAACTACACGGCG

CRISPR arrays and Neighbor proteins around NZ_CP023688_2

CRISPR arrays

The CRISPR arrays of NZ_CP023688_2

>merge|NZ_CP023688|2|1720204-1720352|CRISPRCasFinder
GGCCGACGGGACCCACAGATCCGCCGTCCCCGGTCAGCCCCGCCGCTCGCCACACGCACCACCACGCAGGCCACCGAAAACGGCCCAACTACACGGCGGGCCGACGGGACCCACAGATCTGCCGTCCCCGGTCAGCCCCGCCGCTCGCC

>NZ_CP023688|2|2|1720204-1720352|CRISPRCasFinder
GGCCGACGGGACCCACAGATCCGCCGTCCCCGGTCAGCCCCGCCGCTCGCC	ACACGCACCACCACGCAGGCCACCGAAAACGGCCCAACTACACGGCG
GGCCGACGGGACCCACAGATCTGCCGTCCCCGGTCAGCCCCGCCGCTCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_100246554.1|1722271_1722874_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP023688.1|WP_003981790.1|1726800_1727766_-|LD-carboxypeptidase	unknown	unknown	gnl|CDD|132882
NZ_CP023688.1|WP_078575378.1|1712514_1713435_-|DUF4111-domain-containing-protein	unknown	unknown	gnl|CDD|184296
NZ_CP023688.1|WP_003981787.1|1723161_1724349_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP023688.1|WP_003981783.1|1718551_1720042_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_CP023688.1|WP_003981785.1|1721249_1722221_-|DUF2867-domain-containing-protein	unknown	unknown	gnl|CDD|378548
NZ_CP023688.1|WP_031024440.1|1724635_1726549_-|peptidase-S15	unknown	unknown	gnl|CDD|334820
NZ_CP023688.1|WP_003981791.1|1727762_1729757_-|S9-family-peptidase	unknown	unknown	gnl|CDD|224423
NZ_CP023688.1|WP_003981775.1|1711630_1712497_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|275041
NZ_CP023688.1|WP_003981792.1|1729829_1731194_-|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|181163
NZ_CP023688.1|WP_003981777.1|1713518_1713872_-|hypothetical-protein	unknown	unknown	gnl|CDD|377188
NZ_CP023688.1|WP_003981779.1|1716120_1717026_-|arginase-family-protein	unknown	unknown	gnl|CDD|212523
NZ_CP023688.1|WP_003981781.1|1717544_1717922_-|bleomycin-resistance-family-protein	unknown	unknown	gnl|CDD|319937
NZ_CP023688.1|WP_030184978.1|1713996_1716012_-|DUF5107-domain-containing-protein	unknown	unknown	gnl|CDD|375006
NZ_CP023688.1|WP_151416133.1|1731186_1732020_-|M55-family-metallopeptidase	unknown	unknown	gnl|CDD|176450
NZ_CP023688.1|WP_003981782.1|1717921_1718464_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP023688.1|WP_003981774.1|1710102_1711470_-|cytochrome-P450	unknown	unknown	gnl|CDD|365848
NZ_CP023688.1|WP_003981784.1|1720442_1721204_-|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl|CDD|225002
NZ_CP023688.1|WP_003981788.1|1724398_1724593_+|ferredoxin	unknown	unknown	gnl|CDD|379198
NZ_CP023688.1|WP_003981780.1|1717177_1717513_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_100246554.1|1722271_1722874_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.95067e-10
NZ_CP023688.1|WP_003981790.1|1726800_1727766_-|LD-carboxypeptidase	gnl|CDD|132882	cd07025, Peptidase_S66, LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein. LD-carboxypeptidase (Muramoyltetrapeptide carboxypeptidase; EC 3.4.17.13; Merops family S66; initially described as Carboxypeptidase II) family also includes the microcin c7 self-immunity protein (MccF) as well as uncharacterized proteins including hypothetical proteins. LD-carboxypeptidase hydrolyzes the amide bond that links the dibasic amino acids to C-terminal D-amino acids. The physiological substrates of LD-carboxypeptidase are tetrapeptide fragments (such as UDP-MurNAc-tetrapeptides) that are produced when bacterial cell walls are degraded; they contain an L-configured residue (L-lysine or meso-diaminopimelic acid residue) as the penultimate residue and D-alanine as the ultimate residue. A possible role of LD-carboxypeptidase is in peptidoglycan recycling whereby the resulting tripeptide (precursor for murein synthesis) can be reconverted into peptidoglycan by attachment of preformed D-Ala-D-Ala dipeptides. Some enzymes possessing LD-carboxypeptidase activity also act as LD-transpeptidase by replacing the terminal D-Ala with another D-amino acid. MccF contributes to self-immunity towards microcin C7 (MccC7), a ribosomally encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. Its possible biological role is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	1.10264e-98
NZ_CP023688.1|WP_078575378.1|1712514_1713435_-|DUF4111-domain-containing-protein	gnl|CDD|184296	PRK13746, PRK13746, aminoglycoside resistance protein; Provisional.	2.63775e-61
NZ_CP023688.1|WP_003981787.1|1723161_1724349_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	4.80986e-83
NZ_CP023688.1|WP_003981783.1|1718551_1720042_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	3.15063e-44
NZ_CP023688.1|WP_003981785.1|1721249_1722221_-|DUF2867-domain-containing-protein	gnl|CDD|378548	pfam11066, DUF2867, Protein of unknown function (DUF2867). This bacterial family of proteins have no known function.	8.42418e-08
NZ_CP023688.1|WP_031024440.1|1724635_1726549_-|peptidase-S15	gnl|CDD|334820	pfam02129, Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family).	4.70395e-21
NZ_CP023688.1|WP_003981791.1|1727762_1729757_-|S9-family-peptidase	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	7.09506e-57
NZ_CP023688.1|WP_003981775.1|1711630_1712497_-|methyltransferase-domain-containing-protein	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	7.77308e-61
NZ_CP023688.1|WP_003981792.1|1729829_1731194_-|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|181163	PRK07906, PRK07906, hypothetical protein; Provisional.	0
NZ_CP023688.1|WP_003981777.1|1713518_1713872_-|hypothetical-protein	gnl|CDD|377188	pfam03995, Inhibitor_I36, Peptidase inhibitor family I36. This domain is currently only found in a small set of S. coelicolor secreted proteins. There are four conserved cysteines that probably form two disulphide bonds. Proteins 2SCK31.15C and SCO3675 also have probable beta-propellers at their C-termini. This family includes Streptomyces nigrescens SmpI, a known peptidase inhibitor of known structure. This protein has a crystallin like fold pfam00030 and is distantly related by sequence. It is not known whether other members of this family are peptidase inhibitors.	2.23928e-07
NZ_CP023688.1|WP_003981779.1|1716120_1717026_-|arginase-family-protein	gnl|CDD|212523	cd09999, Arginase-like_1, Arginase-like amidino hydrolase family. This family includes arginase, also known as arginase-like amidino hydrolase family, as well as arginase-like proteins and are found in bacteria, archaea and eykaryotes, but does not include metazoan arginases. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid.	6.99567e-74
NZ_CP023688.1|WP_003981781.1|1717544_1717922_-|bleomycin-resistance-family-protein	gnl|CDD|319937	cd08349, BLMA_like, Bleomycin binding protein (BLMA) and similar proteins. BLMA also called Bleomycin resistance protein, confers Bm resistance by directly binding to Bm. Bm is a glycopeptide antibiotic produced naturally by actinomycetes. It is a potent anti-cancer drug, which acts as a strong DNA-cutting agent, thereby causing cell death. BLMA is produced by actinomycetes to protect themselves against their own lethal compound. BLMA has two identically-folded subdomains, with the same alpha/beta fold; these two halves have no sequence similarity. BLMAs are dimers and each dimer binds to two Bm molecules at the Bm-binding pockets formed at the dimer interface; two Bm molecules are bound per dimer. BLMA belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. As for the larger superfamily, this family contains members with or without domain swapping.	1.42762e-23
NZ_CP023688.1|WP_030184978.1|1713996_1716012_-|DUF5107-domain-containing-protein	gnl|CDD|375006	pfam17128, DUF5107, Domain of unknown function (DUF5107). This family is found in range of different bacterial species. In many proteins it lies N-terminal to a TPR-repeat region at the C-terminus.	3.91374e-33
NZ_CP023688.1|WP_151416133.1|1731186_1732020_-|M55-family-metallopeptidase	gnl|CDD|176450	cd08663, DAP_dppA_1, Peptidase M55, D-aminopeptidase dipeptide-binding protein family. M55 Peptidase, D-Aminopeptidase dipeptide-binding protein (dppA; DAP dppA; EC 3.4.11.-) domain: Peptide transport systems are found in many bacterial species and generally function to accumulate intact peptides in the cell, where they are hydrolyzed. The dipeptide-binding protein (dppA) of Bacillus subtilis belongs to the dipeptide ABC transport (dpp) operon expressed early during sporulation. It is a binuclear zinc-dependent, D-specific aminopeptidase. The biologically active enzyme is a homodecamer with active sites buried in its channel. These self-compartmentalizing proteases are characterized by a SXDXEG motif. D-Ala-D-Ala and D-Ala-Gly-Gly are the preferred substrates. Bacillus subtilis dppA is thought to function as an adaptation to nutrient deficiency; hydrolysis of its substrate releases D-Ala which can be used subsequently as metabolic fuel. This family also contains a number of uncharacterized putative peptidases.	6.0938e-118
NZ_CP023688.1|WP_003981782.1|1717921_1718464_-|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	7.60009e-23
NZ_CP023688.1|WP_003981774.1|1710102_1711470_-|cytochrome-P450	gnl|CDD|365848	pfam00067, p450, Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyze regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.	2.96556e-55
NZ_CP023688.1|WP_003981784.1|1720442_1721204_-|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	3.23289e-32
NZ_CP023688.1|WP_003981788.1|1724398_1724593_+|ferredoxin	gnl|CDD|379198	pfam13459, Fer4_15, 4Fe-4S single cluster domain.	3.26586e-10

Protein sequences

>NZ_CP023688.1|WP_003981783.1|1718551_1720042_-|CoA-transferase
MTHIHPGGTADGAETGVPDQVARGGAAATGLVWAALGGDPALPERVTYGGPSDAAEDLLAARLPVLPAARSAVAVCALAAAELTARRTGRAVPHVHVDDGAVTTAFRSERHLRIDGRAPSAFAPLSRFWRTADGWVRTHANYPHHRARLLAALGLPGTADAADVAAELAERRAAEAEETVYAAGGLAVAVRTPGAWAAHAQGAAMAARPLLTLESIGAGAPPRRLTALDGDPDPLLPAAGLRVLDLTRVIAGPVATRTLALLGADVLRLDAPHLPESPDAHADTGFGKRSATLDLGSRAGRAALDALLATADVVVTGYRPGALDRFGLAPEVLAERRPGLVVARLSAWGGHGPWGGRRGFDSLVQAATGIAVIEGDTDGTPGALPAQALDHGTGYLLAAAVLRALTEQSRTGGTRLATLALARTATWLLDEVPRPDPAPRPTATRPYDPARCLTDSPSPLGPLRHALPPVAFEGGPRNWHRPPGRLGADAPAWEDR
>NZ_CP023688.1|WP_003981782.1|1717921_1718464_-|GNAT-family-N-acetyltransferase
MGDDHYLATGPRVGIRHFTAADRTEFTARARESVPLHRPWLSPPVTDAAYDGYFAKLQEPTREGFLICELETGGIAGFLTVNNIVYAAFRNGAVGYGAFAHAAGRGLMSEGLRLAMRYAFDELGLHRLEINVQPDNERSVALARRAGCRLEGYSPDFLFIDGAWRDHERWAITSDMFEAA
>NZ_CP023688.1|WP_003981781.1|1717544_1717922_-|bleomycin-resistance-family-protein
MSEITFRHPVPVLRVFDVPKAHEFYLGYLGCAVDWEHRFAPELPLYTQVSRGGLVLHLSEHHGDGTPGSVVYTELSGVRALHAELSAKDYPFLSPGLEEDGEIGLTLTLTDPFGNQLRFNEPPAR
>NZ_CP023688.1|WP_003981780.1|1717177_1717513_+|hypothetical-protein
MATQHTYRVIVRGRWDGLTDGARAKLLAEADQHGLAQHRFTPEGSLVYDATLRSFTYRYVIVSDAADGEELAAALAEEKAEAALTAAGYGYRDLRSSATDMDTMKINRKGR
>NZ_CP023688.1|WP_003981779.1|1716120_1717026_-|arginase-family-protein
MRRIVLLDAPSNLGLRPPAPGTVPGCYKLAGALREQGLLRRLGALEGGVVVPPRYDLNGWKEGDGDFNAAAIADYTRRLAARVETHVRAGEFPVLLGGDCSILLGAVLGLRRTGRYGVAYLDGHADFRHPGNTGRNGPVGAAAGEGTAQITGRGQADLTGIDGLAPYVRDTDLHLLGIRDNDEDRPELTGLGISHRTASEIREQGPATVARKVLRDLQDTAPDGFWIHLDADVLDPSVMPAVDSPDPGGLLTPELHDLLAPLAASPRCVGLDLAIYDPDLDPEGTGAALLAGLLESVLAQP
>NZ_CP023688.1|WP_030184978.1|1713996_1716012_-|DUF5107-domain-containing-protein
MATSVRRTTLTLPAAPVGPVSPLPAVRTPGDVHRVELSEDLDLPPDMARQLRYAPLDSLLPESVRDGYGRTRADTALDALVIENDRLRATVLPGLGGRVHSLHHKPTGRELLYRNPVLQPANFALNGAWFSGGIEWNIGATGHTALSCAPVHAATVPAPDGGEMLRLWEWERLRDLPFQVDLWLPEGSDFLYVGVRIRNPHLNAVPAYWWSNIAVPEDEHTRVLAPADAAWHFGYEHRLRRIPVPESDGADRTYPLRSEFPADHFYDIPDGERRWITSLDGSGHGLVHTSTDTLRGRKLFLWGAGRAGRRWQQWLTEPGTGGYAEIQAGLVRTQLEHVRLDGGAEFAWLEAYGPLAADPAAVHGTDWAAARREVGDRLEAALPRAEVDAAFAAWRPHADLEPKETLATGSGWGALERARTGHDLPGTPFAESTIGPEQRPWLALLHTGDFPRDAGVPTAPLVSAPWRDLLESAPPGPATDYHLGIAQWHAGDRAQAVRSWERALAHGTDCRPLYCLAVAEETEGETARAAQRYAEALACVTDDETGPEHTAPLLPALVRAAVPALLAAGRTDEAAAALDRIPAAARTNGRFALLTAQVALARGDAPAARAVFDRGFEVPDLREGDETLSDTWYAIADRLTAGTGPVTPAVHAKARAEHPLPERYEFRMREV
>NZ_CP023688.1|WP_003981777.1|1713518_1713872_-|hypothetical-protein
MSPLKTLVRSTGVLAAAGCLGFTVMSAPAQAASGACEQNHVCLWSGKNFTGTSGKIAAQPGKCYNSRSVPAQSMNNNTRYFLRTFPKANCKGHGWTMNWGTKSNDLPQGVMSFMPVK
>NZ_CP023688.1|WP_078575378.1|1712514_1713435_-|DUF4111-domain-containing-protein
MDQLAQTAGLVSDVLGPDLLGTYLHGSAVLGGLAPASDLDVLAVTRRSLDDRQRRALLAGLLEISGLTAAVRPVELTVVVQSEVRPWRFPPTGDFLYGEWLRDTLRASGPPMPEPMPDLALVLTMVLAGDHPLTGPPPAELLDPVPHPDLVRASVESIPGLLADLADDTRNVLLTLARIWTTLATGHVVPKHTAADWALTHLPAQHRPALQHARDLYLTTLYEDEVWPRELMEQVRPHVDEVLARTLALRRHPLDTVPVGSAWAKGAVMGHRQEQNGQVGGDFASPGEPGSPMPQDDTPAEDEDDE
>NZ_CP023688.1|WP_003981775.1|1711630_1712497_-|methyltransferase-domain-containing-protein
MVDAVALRRGCVAAIDGYGGGYFHERDWLRAAFLEVPREHFVPDRVWWPTRRDGRFPLLDRNERPGQWLKAVYRPLAALITQIDDGRVRPEDGPAAEGCFTSSVSCSAVIVDMLHHLDPQPHERVLEIGTGSGYTTALLARRVGAANIVTVEIDPDLARRAAGNLDALGLAPHAVVGDGEGGYAAAAPYDRILSTAAVRHIPAAWPRQVRPGGVIITPIDTPYNTDALLRLVCDGQGNATGRLIKPVTFMKTRAQRPRRSYGELGWPGWSEHRVTVGADGQRIDMGRP
>NZ_CP023688.1|WP_003981774.1|1710102_1711470_-|cytochrome-P450
MASRTRIDTPGRNEHRLHTVPLRHVLGGLRAGGPLGLMERTGRRSQGALTRLELGAFRPFLVTHPDHLRHVLRDHGANYRRGTAMWKAMGRLTGMGIAGEGPQWRASRELWCRGLSGGAHVFADGTADAVAGAVADLERRVAAGATVDALTEMTRVVLRVVNPAFFGSRIPQGECDRLAAAVAVAFDSLLWRMALPFVPLAVPLPGDRAFTRATRTVNGILLPLIRRARHAHHRGPDLMSTLLDGADADGRALGDAHVAQDIVAMFVAGSESSALTLTWAWVALAGHADIAAEVRREADAVLGGGPPRPEHARRLVFTRRVLAEVCRLYAMAWAVPRTAVAEDVIGGVTVPAGATLVLSPYLTHRLPAFWERPLRFDPGRFTDERVRGRHPLAYLPFGDGPHQCVGQSFFFQQAALVVATMMSRFRIAVPTPAEPRAAVALRPRSRVDLALTPRG
>NZ_CP023688.1|WP_003981784.1|1720442_1721204_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MTTGDTWAPSDECGAARPALIPEVYDSAALPGPLPADGPPAVSLWLVRTVPEAGLHDTAVLDAGERKRTAAFVRPGDRDTYATSHSALRRLLGAYLDRDPAALRFVREPCPCCDEPHGRPALAGAGMPLHFSLSHTGDMALIGFARTPVGVDIEKPASPRTVAEVSGMLHPQERATLDALPEAGRPAAFARCWTRKEACLKGKGSGLAGDLMTTTLVGAGPVPIPVPGWEMADVTVPDGYAAACAVRTGGVGG
>NZ_CP023688.1|WP_003981785.1|1721249_1722221_-|DUF2867-domain-containing-protein
MRTVRDVHARTIDAPAGKVGALLDRLAGDDDPLFPVPVWPAMRFDRPLGTGATGGHGFVRYRVTAYEPGRRVRFGFPDGGHHAFEVTPLDAKSCRVTHVLEHGHRGARRLAWPLAVRWLHTTVVEEVLDNVERAATGTVSAPVRRSPYVQLLNRLLWDRPTAVGLPAGARLARTAFARTDFEDAWQLPLPPGMPRDPAAWKGVLRGAFPEQGRATTADGGELLLGKDARHLDFRASILVESPAAGVDGRTVGHGGRVTLSTVVRTHHAGGRLYFALVRRVHPVLARAMLRRTHRRLALAAPSAGEREWAARAPRAGYGHRTRP
>NZ_CP023688.1|WP_100246554.1|1722271_1722874_+|TetR/AcrR-family-transcriptional-regulator
MAPQRTGDRTKPKGTRRRLTARDWAEAALAAIGEGGLAAVAVEPIAARLGTTKGSFYWHFANREALVDAALELWEQSHTEAVITELAAEPDPERRLRALFAYATAASADDPLEVALLATAADPRVAAALRRVTDRRVGHLAELFAALGFPEAEARRRGLLAYTAYLGHTQLSHAVPGSLPQGPDRDGYLDSVLDTLLHQD
>NZ_CP023688.1|WP_003981787.1|1723161_1724349_+|cytochrome-P450
MTEALPFPQDRTCPYDPPAGYQPLRDSRPLSRVTLYDGRPAWVVTGHAESRALLTDPRLSADRQNPAFPSPAPRFETLRKVRTPLLGVDDPEHNTQRRMLIPSFSVKRAAALRPRIQEIVDRLLDAMEQQGPPAELVSAFALPVPSMVICALLGVPYADHELFEGLSRTLLQSADPQEVTEARDKLEDYFTALVERKRKEPGDGLLDELIAERLDSGELGHRELVRMAMLLLVAGHETTSNMLSLGTFTLLEHPEQFAALRADPSLLPAAVEELLRFLSIADGMVRVATEDIEIGGVTIRADDGVIFSTSVVNRDGAAYASPDTLDWERSARHHVAFGFGVHQCLGQNLARAEMEIAFGALFARFPGLRLAVPAAEIPVKPAHALQGLVELPVTW
>NZ_CP023688.1|WP_003981788.1|1724398_1724593_+|ferredoxin
MKIDIDTSVCIGSGQCVLTAPGVFTQDDDGFSTLLPGREDGTGDPLVREAARACPVQAIAVTDD
>NZ_CP023688.1|WP_031024440.1|1724635_1726549_-|peptidase-S15
MEVCVPSVSSALPGAASRPVRRAARTRSARLPVTASVCLAACAALLGPVTAAGPAGAAGPRQPGYAVTPLKLPVRAGGRDCNLDADLYRPTGVDALHPAPAVVTTNGFGGSKSDGSTDAIARAFASRGYVALAYSGLGFGRTGCPISLDDPRIDGRAASQILDFLAGQRAAKNGVRVDFVTKDGPRDPRVGMFGGSYGGAIQLATASADERLDALVPLITWHDLTYALAPNNADRTSGVAGPAPGAYKHQWTNGFYLIGEAQGLLHPRLDPSRGGGAGCVHFVAPACELKKRLNSNRYPSAPTEAALDYARSVSPTSYLATVRTPTLLVQGQADTLFNLNEAAATFETLRAQGTDTAMIWQSWGHSGGMTDPAPGELDLGKGNFDTSYVGRRTLAWFGRYLRREWDTDTGPAFAYYRDWAAHGPAYAASEVYPVGIPRRLYLSGDGKLVDNPADVATGSRHYRNWRVASSHSESSLAALMKLPNPKPYDTRGTYLDWASEPVRGRPVDVVGSPRATLRVHSPDAERTQHSDDAADRLLLFLKLYDVAPNGGKTLVHRLVAPVRVPDVTREFTVNLPAIVHRFAPGHRLRLVMAAGDTAYFGNRGSKQVTVSSTRARTGTLDLPVVGEGVEGLDDDLP
>NZ_CP023688.1|WP_003981790.1|1726800_1727766_-|LD-carboxypeptidase
MTGAGSAVAGDRPRRLVPGDRVRIVAPSGPVAPERLDAGADLLRGWDLDPVEAPHVRGRHATLPYLAGTDEERARDLQEALCDPGVAAVFAARGGYGAQRVADLLDWAAVRAAFRAHGPKALVGFSDVTALHEAFAVRAGVATLHGPAVAGEVFLKDEPTREHLRRTLFAPGSVRVVTSPAARPLVPGRARGVTLGGCLSLLAADLGTPHARAVAAGGLLLLEDVGEPPYRVDRALTQLLRAGWLDGVAGVVLGSWARCGPYEDLRAVLLDRLGPLGVPVVEEFGFGHGDSALTMPLGIRAELDAAAGTLTYDVPALREGP
>NZ_CP023688.1|WP_003981791.1|1727762_1729757_-|S9-family-peptidase
MVTTAPYGAWPSPIDARLVAEHDGRPEYVGVVGAEVWWTEARPAEGGRRALVRRGLDGTEETVLPAPWNVRSRVIEYGGQPWAGAVDADGRTVVVFCDFADQRLYAYTPDDGAAPRPLTPVSAVGGGLRWADPVLRLDRGEVWCVLEEFTGPRPTDVRRVIAAVPLDGSAAEDRTVVRELSDDRHRFVTGPRISPDGRHAAWIAWDHPRMPWDGTVVLLAGITGGGAFTGVREFAGGPEESVAQVEWDADGTLLYVSDADGWWELRRADPAEPDGTPGRRLCPPRQEEFGGPLWKIGMRWFLPLDGGTIAVVHGRGATSLGILDPVSGDLVDAAGPWTQWAPSLAVHGSRVIGIAAGPRSAHEIVELDTCTGRARVIAARHTDAVDPAYYPEPQSRTFTGPDGRDIHAHIYPPHNPGHRAPDGELPPYVVWAHGGPTGHAPLVLDLEAAYFTSRGIGVAVVNYGGSTGYGRAYRERLRGQWGVVDVEDCAAVAEALADEGTADRRRLAVRGGSAGGWTAAASLVTTGLYACATISYPVLDLVGWSEDGTHDFESQYLESLIGPHDQVPDRYRERSPLHHADRISAPFLLLQGLDDAVCPPAQCDRFLRAVAGRGTPHAYLAFEGEGHGFRRAETIVRAVEAELSLYAQTFGIARTDVPPLELTK
>NZ_CP023688.1|WP_003981792.1|1729829_1731194_-|M20/M25/M40-family-metallo-hydrolase
MADSADDMADRAGDAVDGQALDEVVRFTSDLIRIDTTNRGGGDCRERPAAEYVAERLAEAGLEPVLLERTPGRTNVVARVEGTDPDAAALLVHGHLDVVPAEPADWTRHPFSGEVADGVVWGRGAVDMKNMDAMVLAAVRQWARSGVRPRRDLVLAFTADEEASAIDGAGFLADHHPGLFEGCTEGISESGAFTFHAGGGMRVYPVAAGERGTAWLKLTAEGRAGHGSKVNRANAVSRLAAAVARIGEHRWPVRLTDTVRAALTELAALHGIEARLDAPDFDVDTLLSKLGPSAALVEPTVRNSANPTMLEAGYKVNVIPGNAVAHVDGRVVPGGEAEFRTTMDRLTGPDVTWAYDHGEVALQAPVDSPAYAAMKAALQHFDPGGHVVPYCMSGGTDAKQFSRLGITGYGFSPLKLPEGFDYQALFHGVDECVPVEALHFGVRVLDHFLRSVEG
>NZ_CP023688.1|WP_151416133.1|1731186_1732020_-|M55-family-metallopeptidase
MKILISADMEGATGVTWPDDVLPGHAQWQRFRPVFTGDVNAAVAGFFAGGADEVLVNEAHWSMRNRLLEELDERAQLLTGKHKALSMVEGVQYGDVDGVAFIGYHAGAGTEGVLAHTYLANSLTGVWVNGTRASEGYLNSLVVAEYGVPVVLVTGDDRTCDDAAGYAPDARAVAVKDYVSRYAAVCRPPARTAADIRAAAREAAALAVRTEPVRGGPYTVEMEFDAEHLVGQATCVPGVERTGERRVAYTSENMYEAIRCFKTVTTVVSSAVEEQYG

Crispr_ID: NZ_CP023688_3

• CRISPR_ID: NZ_CP023688_3
• CRISPR_location: 2659543-2659627
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP023688_3

Consensus_repeat	Method
CGGCCCCGTACGGGTGGCGGGCGG	CRISPRCasFinder

spacers of NZ_CP023688_3

>3.1|2659567|37|NZ_CP023688|CRISPRCasFinder
ACGCGGTCGGCGTGCGCGCCGTCGCCCACCGCGCCGA

CRISPR arrays and Neighbor proteins around NZ_CP023688_3

CRISPR arrays

The CRISPR arrays of NZ_CP023688_3

>merge|NZ_CP023688|3|2659543-2659627|CRISPRCasFinder
CGGCCCCGTACGGGTGGCGGGCGGACGCGGTCGGCGTGCGCGCCGTCGCCCACCGCGCCGACGGCCCCGTGCGGGTGGCGGGCGG

>NZ_CP023688|3|3|2659543-2659627|CRISPRCasFinder
CGGCCCCGTACGGGTGGCGGGCGG	ACGCGGTCGGCGTGCGCGCCGTCGCCCACCGCGCCGA
CGGCCCCGTGCGGGTGGCGGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_043979291.1|2659757_2660216_+|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NZ_CP023688.1|WP_003980168.1|2662847_2664197_+|4-aminobutyrate--2-oxoglutarate-transaminase	unknown	unknown	gnl|CDD|235685
NZ_CP023688.1|WP_030182293.1|2653702_2654389_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP023688.1|WP_003985887.1|2655946_2657392_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143465
NZ_CP023688.1|WP_050498902.1|2670953_2672300_-|NDP-hexose-2,3-dehydratase	unknown	unknown	gnl|CDD|367562
NZ_CP023688.1|WP_003980172.1|2667410_2668571_+|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl|CDD|99740
NZ_CP023688.1|WP_003985895.1|2645663_2646509_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379120
NZ_CP023688.1|WP_078575588.1|2654363_2655620_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP023688.1|WP_003985892.1|2649340_2650612_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl|CDD|235472
NZ_CP023688.1|WP_030182295.1|2657734_2659396_-|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|377939
NZ_CP023688.1|WP_003985893.1|2648042_2649344_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100084
NZ_CP023688.1|WP_003980170.1|2665175_2666216_-|L-tyrosine/L-tryptophan-isonitrile-synthase-family-protein	unknown	unknown	gnl|CDD|368301
NZ_CP023688.1|WP_003980174.1|2669727_2670954_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|378005
NZ_CP023688.1|WP_003980167.1|2660445_2662608_-|ATP/GTP-binding-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003985894.1|2646706_2647864_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl|CDD|234737
NZ_CP023688.1|WP_003980173.1|2668574_2669708_+|DUF1205-domain-containing-protein	unknown	unknown	gnl|CDD|275309
NZ_CP023688.1|WP_003985890.1|2651542_2653462_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173850
NZ_CP023688.1|WP_078575578.1|2666212_2667412_-|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl|CDD|225086
NZ_CP023688.1|WP_030182291.1|2650687_2651512_+|DUF1963-domain-containing-protein	unknown	unknown	gnl|CDD|370378
NZ_CP023688.1|WP_100246491.1|2664300_2665212_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_043979291.1|2659757_2660216_+|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	5.47482e-23
NZ_CP023688.1|WP_003980168.1|2662847_2664197_+|4-aminobutyrate--2-oxoglutarate-transaminase	gnl|CDD|235685	PRK06058, PRK06058, 4-aminobutyrate--2-oxoglutarate transaminase.	0
NZ_CP023688.1|WP_030182293.1|2653702_2654389_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.03656e-70
NZ_CP023688.1|WP_003985887.1|2655946_2657392_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143465	cd07147, ALDH_F21_RNP123, Aldehyde dehydrogenase family 21A1-like. Aldehyde dehydrogenase ALDH21A1 (gene name RNP123) was first described in the moss Tortula ruralis and is believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and ALDH21A1 expression represents a unique stress tolerance mechanism. So far, of plants, only the bryophyte sequence has been observed, but similar protein sequences from bacteria and archaea are also present in this CD.	0
NZ_CP023688.1|WP_050498902.1|2670953_2672300_-|NDP-hexose-2,3-dehydratase	gnl|CDD|367562	pfam03559, Hexose_dehydrat, NDP-hexose 2,3-dehydratase. This family includes a range of proteins from antibiotic production pathways. The family includes gra-ORF27 product that probably functions at an early step, most likely as a dTDP-4-keto-6- deoxyglucose-2,3-dehydratase. Its homologs include dnmT from the daunorubicin biosynthetic gene cluster in S. peucetius, a similar gene from the daunomycin biosynthetic cluster in Streptomyces sp. strain C5, eryBVI from the erythromycin cluster in S. erythraea and snoH from the nogalamycin cluster in S. nogalater. The proteins in this family are composed of two copies of a 200 amino acid long unit that may be a structural domain.	2.16574e-101
NZ_CP023688.1|WP_003980172.1|2667410_2668571_+|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	7.38369e-122
NZ_CP023688.1|WP_003985895.1|2645663_2646509_-|GNAT-family-N-acetyltransferase	gnl|CDD|379120	pfam13312, DUF4081, Domain of unknown function (DUF4081). This domain is often found N-terminal to the GNAT acetyltransferase domain, pfam00583 and FR47, pfam08445.	1.79842e-48
NZ_CP023688.1|WP_078575588.1|2654363_2655620_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.35248e-39
NZ_CP023688.1|WP_003985892.1|2649340_2650612_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl|CDD|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP023688.1|WP_030182295.1|2657734_2659396_-|PucR-family-transcriptional-regulator	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	4.05368e-28
NZ_CP023688.1|WP_003985893.1|2648042_2649344_-|site-2-protease-family-protein	gnl|CDD|100084	cd06163, S2P-M50_PDZ_RseP-like, RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog RseP is involved in the sigmaE pathway of extracytoplasmic stress responses. Also included in this group are such homologs as Bacillus subtilis YluC, Mycobacterium tuberculosis Rv2869c S2P, and Bordetella bronchiseptica HurP. Rv2869c S2P appears to have a role in the regulation of prokaryotic lipid biosynthesis and membrane composition and YluC of Bacillus has a role in transducing membrane stress. This group includes bacterial and eukaryotic S2P/M50s homologs with either one or two PDZ domains present. PDZ domains are believed to have a regulatory role. The RseP PDZ domain is required for the inhibitory reaction that prevents cleavage of its substrate, RseA.	1.88819e-48
NZ_CP023688.1|WP_003980170.1|2665175_2666216_-|L-tyrosine/L-tryptophan-isonitrile-synthase-family-protein	gnl|CDD|368301	pfam05141, DIT1_PvcA, Pyoverdine/dityrosine biosynthesis protein. DIT1 is involved in synthesising dityrosine. Dityrosine is a sporulation-specific component of the yeast ascospore wall that is essential for the resistance of the spores to adverse environmental conditions. Pyoverdine biosynthesis protein PvcA is involved in the biosynthesis of pyoverdine, a cyclized isocyano derivative of tyrosine. It has a modified Rossmann fold.	3.6461e-104
NZ_CP023688.1|WP_003980174.1|2669727_2670954_-|methyltransferase-domain-containing-protein	gnl|CDD|378005	pfam08484, Methyltransf_14, C-methyltransferase C-terminal domain. This domain is found in bacterial C-methyltransferase proteins. This domain is found C-terminal to methyltransferase domains such as pfam08241 or pfam08242. But this domain is not a methyltransferase.	2.50987e-74
NZ_CP023688.1|WP_100246491.1|2664300_2665212_+|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	5.87764e-31
NZ_CP023688.1|WP_003985894.1|2646706_2647864_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl|CDD|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NZ_CP023688.1|WP_003985890.1|2651542_2653462_-|acyl-CoA-dehydrogenase	gnl|CDD|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	4.8366e-94
NZ_CP023688.1|WP_078575578.1|2666212_2667412_-|TauD/TfdA-family-dioxygenase	gnl|CDD|225086	COG2175, TauD, Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	8.85431e-45
NZ_CP023688.1|WP_030182291.1|2650687_2651512_+|DUF1963-domain-containing-protein	gnl|CDD|370378	pfam09234, DUF1963, Domain of unknown function (DUF1963). This domain is found in a set of hypothetical bacterial proteins. Its exact function has not, as yet, been described.	6.59371e-34
NZ_CP023688.1|WP_003980173.1|2668574_2669708_+|DUF1205-domain-containing-protein	gnl|CDD|275309	TIGR04516, probable_glycosyltransferase, glycosyltransferase, activator-dependent family. Many biosynthesis clusters for secondary metabolites feature a glycosyltransferase gene next to a P450 homolog, often with the P450 lacking a critical heme-binding Cys. These P540-derived sequences seem to be allosteric activators of glycosyltransferases such as the member of this family. This model describes a set of related glycosyltransferases, many of which can be recognized as activator-dependent from genomic context.	8.50384e-54

Protein sequences

>NZ_CP023688.1|WP_030182295.1|2657734_2659396_-|PucR-family-transcriptional-regulator
MPHTLASLVHHSALKLTVLAGADRLATPVRWAHASELIDPVPYMEGGELLLITALKLDAEDPETARRYVRRVAGAGVVGLGFAVGVNYEDVPQALVTAAEEEALPLLGVPRSTPFIAISKAVSAAVAADQYRAVTEGFEAQRELTRAALGAEGPAELLARLAAHLKGWAALYDASGAVVAAAPDWAARRAARLGDDVGRLRERPAPASSVVSEAAGDDRVELQSLGTGRRARGVLAVGTGAPLGTAERFAVHSAVALLTLTTERSRALQEAEQRLGAAVLRMLLAGEPDHARAVAGRLYGGLLDAPFRVVVAESVAADGADGAESAGGPPALDALADAMESAAARTGEAVLAVPEGGRLVVLAADGGAAAEACAEHAATAEARFGGQPLPRGRAARAEAGRSGEGLAIGLSAPSGPRDAAHAYRQAEQALSVARRRGRVLVEHEDVAAGSVLPLLADDAVRAFADGLLRALHEHDATGRGDLVASLRAWLSRHGQWDAAAADLGVHRHTLRYRMRRVEEILGRSLDDPDVRMELWLALKTTAAVTEPYGGGTT
>NZ_CP023688.1|WP_003985887.1|2655946_2657392_-|aldehyde-dehydrogenase-family-protein
MTSPTAFWLAGRQATGEDTFAVTSPWDGRLVGTVSVPTEAQVEEAVAASVAVQAELSATPAHVRAAALDHVQRRLVERTEEIARLISAENGKPMKWARGEVGRAVSVFRFAAEEARRFNGGEAQRLDTDAGGAGRLALTRRFPRGTVLGIAPFNFPLNLCAHKIAPAIAAGVPIILKPAPATPLSGLILGELLAETDLPAGSWSILPVSNDRMPALVQDERLPVISFTGSEKVGYAIMDSVPRKHCTLELGGNGAAVVLADFASEADLDWAAQRIATFSNYQGGQSCISVQRVIADASVYDRLVPKIVAAVNAQVTGDPSDDETEVGPLVSEDAAKRVEAWVDEAVGAGAKLLAGGKRDGASYAPTVLEGVPAGVTLACEEVFGPVLSLTKVDGEEAAFAAVNDSKYGLQAGVFTHDVQAAFRAHRELEVGGVIIGDVPSYRADQMPYGGAKQSGVGREGVRFAMEDYTYERVLVLTGLDL
>NZ_CP023688.1|WP_078575588.1|2654363_2655620_-|sensor-histidine-kinase
MDTAVAAAFATVSLLLGHDNAPAGWHRLDGLGSVLTCLINLLLVARRRAPVAVCLSVFLLWFAYIALDYWPVVNSLAGLMALYTVASHRPPRVAAGCSVLLAALWNFAGTTGNESAWPTTLGQSVLYTVILCWFGNVARTSAERNVRLTEMAGQLRREKEENARRAVADERVRIARELHDVVAHHMSVISVQAGLAGYVFASDPDTARRALGTIAGTSGEALEEMRRLLAVLRVDPREMAGGPAAVDRSETGEGEDAAAYEPAPGLDRIGGVVERVRAAGLPAELRTTGERRPYAPGLEQCAYRVVQEALTNALKHARGARVVVLVHHGAERLTVEVRDDGGPPAEAAAPPATSGHVSTGHGLIGMRERARIYGGSLRAGPLPGGGFQVRLTLPVHPGAGPAPPRKGTTEHDQGAGGR
>NZ_CP023688.1|WP_030182293.1|2653702_2654389_-|response-regulator-transcription-factor
MIRVLVADDQVLIRAGVAALLRAAPDVEVVAEASDGEEAVRLAAEHRPDVILMDIRMPGVSGITATERILRGAAEAGEPAPRVVVLTTFDLDEYVYAALRAGASGFLLKDTPPQRLLSALATVAGGDMLFAPSVTRRLVEAYARQRDEPGREAADGPETLQALTARELEVLRHTAKGLSNPEIAARLVISEATVKTHLNRTMAKLGLCSRAQAVVLAYETGLVTPGAR
>NZ_CP023688.1|WP_003985890.1|2651542_2653462_-|acyl-CoA-dehydrogenase
MTAPSTRNVSEREARQVAEAAREQDWRKPSFAKELFLGRFRLDLIHPHPTPATEDAQRGEEFLAKLRDFCETKIDGARIEREAQIPDETIDGLKEIGALGMKIDTKYGGLGLTQVYYNKALALVGSANPAIGALLSAHQSIGVPQPLKLFGTQEQKDTFLPRCARTDISAFLLTEPDVGSDPARLATMAVPDGEDYVLDGVKLWTTNGVVADLLVVMARVPKSEGHKGGITAFVVEAAAEGVTVENRNAFMGLRGIENGVTRFHRVRVPAANRIGPEGAGLKIALTTLNTGRLSLPAMCVGAGKWCLKIAREWSAAREQWGKPIAEHEAVGSKISFIAATTFALEAVVDLSSQMADEDRNDIRIEAALAKLYGSEMGWLMADELVQIRGGRGFETAASLAARGERAVPAEQILRDLRINRIFEGSSEIMHLLIAREAVDAHLSVAGDLIDPEKSLGDKGRAAAKAGTFYARWLPKLVAGPGQLPRTYTEFGELAGHLRYVERAARKLARSTFYAMSRWQGRMETKQGFLGRIVDIGAELFAMSAAVVRAEHLRATDDHGREAHQLADVFCRQARIRVDELFGRLWTNTDDLDRKVVSGVLTGTYAWLEEGVVDPSGDGPWIADATPGPSAKENVHRPIR
>NZ_CP023688.1|WP_030182291.1|2650687_2651512_+|DUF1963-domain-containing-protein
MERTMSPPARLAAELMPAGAAERWTALLRPAVRLTRPDDRRAPLAGPPVGYLGGRPELPDDVPWPVWEGNGPLTFVASLSLSALAGADLDIPLPEDGTLLFFVSYGPGQGDGVPGLGPEGQRGARVVYVPEGTPVAERRVPGGLEEPYRRVPLSAEPEMTWPDREEFWLGDLVGASPGDELPEWVDAFDDALIDLSPKIWHRVGGYPIPIQGGLDCDFLGADEDPDDWVLLAQIDSDDRARMEWVHQGTLYWLISRADLAARNFAGARFTWQFL
>NZ_CP023688.1|WP_003985892.1|2649340_2650612_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MTDTLADPHLRFVPAPLTGDGDGPRDIVILGSTGSIGTQAIDLVLRNPDRFRVTALSAAGGRVELLAEQAHQLRVRTVAVAREDAVPALREALSARYGAGERLPEILAGPDAATEVAALDCHTVLNGITGSIGLAPTLAALKAGRSLALANKESLIVGGPLVKAQARPGQIVPVDSEHSALFQGLLGGPRSEVRKLVVTASGGPFRGRTKAELASVTPEQALAHPTWAMGPVITVNSATLVNKGLEVIEAHLLYDVPFDRIEVVVHPQSYIHSMVEFTDGSTLAQASPPDMRMPIALGIGWPDRVPDAAPGIDWTRAHQWDFLPLDTEAFPSVPLACHVGDLGGTAPAVFNAANEECVDAFLKGGLPFTGIVDTVAEVVARHGTPDRGTSLTVADVLQAETWARARARELAARAARTTSEARA
>NZ_CP023688.1|WP_003985893.1|2648042_2649344_-|site-2-protease-family-protein
MTTWMTVLGIVVFVVGLLFSIAWHELGHLSTAKMFGIRVPQYMVGFGPTLFSRRKGDTEYGIKAIPLGGYIRMIGMFPPGEDGAITARSTSPWRGMIEDARSAAFEELQPGDEKRLFYTRKPWKRVIVMFAGPFMNLILAVVIFMGVLMGFGINTQTTQVGSVSDCVIAASAKTDKCTKGAKDSPAKAAGLRAGDKIVDFNGKPVPDWGSLQQSIRDTTGPATITVERDGKRQQLHANLIENKVAKTDGHGSYVPGEYVTAGFLGFTPATGIVQQSFGQSVDRMGNMVEQGVQSLVNLPAKVPDLWDAAFNGGERKQDSPMGVVGAARVGGEVFSLNIPPEQRVATMLFLVAGFNLSLFLFNMLPLLPLDGGHIAGALWESVRRAFARVFRRPDPGPFDVAKLMPVAYVVAGIFICFTLLVLVADVVNPVKLT
>NZ_CP023688.1|WP_003985894.1|2646706_2647864_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MTAISLGMPDVPTKLADRRVSRQIQVGPVAVGGDAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALPVIARKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIKQFDDKVKEIAKAASDAGTPIRIGVNAGSLDRRLLQKYGKATPEALVESALWECSLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEVKVGLQILESLNLRPRRLEIVSCPSCGRAQVDVYKLADEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEAMKIAEQMEKDGVTSGEPTISVAG
>NZ_CP023688.1|WP_003985895.1|2645663_2646509_-|GNAT-family-N-acetyltransferase
MLTTTTTKVLEPGELDDALAVLDRDPVANAFVAARVQVAGLDPWRLGGEMWGWYADGRLESLCYAGANLVPVCATPEAVRGFAERARRQGRRCSSIVGPAGPTAELWSLLEPAWGPAREVRAQQPLMVTSSFASEVEPDPYVRRIGKHEMDLIMPACVAMFTEEVGISPLAGDGGLLYQARVAELVGAGRSFARVDDGKVVFKAEIGAATPRACQIQGVWVAPEYRGKGLSETGMAAVLRYALTEVAPVASLYVNDFNTAARAAYRRVGFQETGAFMSVLF
>NZ_CP023688.1|WP_043979291.1|2659757_2660216_+|RidA-family-protein
MARFTTVPGLFPPPRYSHAAVVEAGERLVFTAGAVPLDADGNLVGPGDVATQTRQVLGNLATQLEAAGSGLDRVIASTVYVAATTTEALSTAWEEVRASALSTGPHTSTLVGVTVLGYPGQLVEITATGVVREDPVDSAPHGAARREERGGL
>NZ_CP023688.1|WP_003980167.1|2660445_2662608_-|ATP/GTP-binding-protein
MDTEGTQHDAPHTRTDHHVPRPAAPPVPPAPPSAPSARPSPGIPPVPSAPPAFEDGAFLRWLRAPRRAAAPGIWTYGHVPRPAENPDRVPTRQLVTGALISFLCGWLLWSLLWNGYLGPYWLYPLLLLTPDSWRSAGGDKMIFVTLTYLYYALVLAVLVLVFGRLGRWRELGRRLLGPVLRRAREQRPDAVPEPEADRAQWPALRAGGAPDAADKLAAEALAGRMNDVDVSRIERAWHSVRSGKNSLASFTDTVLRHGAAACAHPSGLRDLPARAAHHDLLAQQVRIGTATDHPRNPHAHRGAGCALDPALLGTSLLAVGPPGCGKTTRVVRPVVEAMCLQALAGRGAVVAVGAAGSALGPDDAFDAVVRIGAPEPDCDIDLYGGTTDPDEAAGILAEALVGDLAATLPGGDSRRAATALGQLLGPYRAAHGRFPSVPELRELLDGSATALDALRDALEAAGAQPLLRELDARARQSGRPGDIGDLLADRVALLDRPAFAPYFDPEGGDRQISLRALDHPLRVRIDLPERGHAEASRILARLVLAQFTECAAARTDRSLFACLVLDDAAHTVTAESLRGLQRLRAANAGVLLTLRSLDDVPESLRSALLGAVGCRMAFAGVTTWDGARFAEVWGKEWVETRDVTDRQIIAEGAAMKAFHIFRHLVTGKAATAKAVTVRTVERERWSASDLANSVPPGHAVLSVTSVRGEHAPPVLVDLRG
>NZ_CP023688.1|WP_003980168.1|2662847_2664197_+|4-aminobutyrate--2-oxoglutarate-transaminase
MTELSGGPALPQERRVVTAIPGPKSQELWARKQATVAGGVGAVLPVFAKRAGGGILEDVDGNSFIDFGSGIAVTSVGNSAEAVVRRATAQLADFTHTCVMVTPYEPYVEVCEQLAELTPGDHAKKSALFNSGAEAVENAVKIARAYTKRQAVVVFDHGYHGRTNLTMALTAKNMPYKHGFGPFAPEVYRVPLAYPYRWLTGPENCAKEAADQAISQITKQIGAENVAAIIIEPVLGEGGFIEPAKGFLPAIADFAKENGIVFVADEIQSGFCRTGQWFACEDENIVPDLITTAKGIAGGLPLAAVTGRAEIMDAAHAGGLGGTYGGNPVACAAALGAIETMRELDLNAKARRIGEIMKPRLQAMADKHDIIGEVRGRGAMIAIEIVESGSKEPNPKATAALAAACHQEGLLVLTTGTYGNVLRFLPPLVIGEDLLNEGLNIIESALATV
>NZ_CP023688.1|WP_100246491.1|2664300_2665212_+|phosphatase-PAP2-family-protein
MRDTPRSREAVSDARPGLPRLRPGRAFAHTSGAPRPGHPHRSDGRPPQTPRGARRSGQRGRLGTTPPVPRRPAFFLRRGLLPAVLCAVLFTVLAWQVASGGPLCALDERLGRTLVHSAMPASLAEFFADLGNTVVALPVLALAALHAAWRGRRAAAPRWWLAPLAAVLTMAVVPALVVPLKVWLARPGPPEMAGGAHTGFFPSGHAATAAVAYGSVALLLTALREHPRSPMPAAVAVIGVGLLNLAVGIGLVRRGYHWPLDVLASWCLAGVLLTVCTAVCGRWAAHPHQPDSQLATSNSSDAM
>NZ_CP023688.1|WP_003980170.1|2665175_2666216_-|L-tyrosine/L-tryptophan-isonitrile-synthase-family-protein
MTVTYEQHAERPAQGEDEGDAAYEAATRQYCAQILELLLPHRRPVGAPDEAAAGDGGPHDGHRPEECFAEQLAQLRDFVARREPVLLTLPAFPCKSPNPAKVAGHLPDLGELLSLRFLDDLCVAIGAVYPPGARLLICSDGHVFGDLIRVPDAHIDAYGKALRDMIEATGLKHIDTFGLDQVYEDRTYDEKRALLERDHAQSLEELRDEVRGGGPALSHYRGTIRFLVEDTANWTGSKAQLQRECRGRAYGVLRRSRAWGELIAHHYPRNVRLSIHPQPCGAAKFGIALLEAADNWLTPWHAVVVQTGTDRFRLMKRHEAERVGIPAGPSWRPSHYIASELFDVAS
>NZ_CP023688.1|WP_078575578.1|2666212_2667412_-|TauD/TfdA-family-dioxygenase
MSWSSHPRRGGCLGRVWGGAWGPGSGRRGTEAAMDGSVRRRCLPRTGRRRKGHICQRDVTRRWKALETSSTVAVPCPADRPGTPLSRRGTMTSQAVPASGPATAAALDDTRSWTLAEPGPFGVLITPAEPGTPVTAVPVPWLRDLARRHHLVALRGFTPPADATALDAYARTWGEVMEWPFGTVFDVRAHQDPEDHVFDTGFMPLHWDGMYVEHVPEFQIFHCVAAPEAAEGGGTLFCDTTRVLADADPETLERWRGLTLSYRNAKVSHYGGLVVSPLIEPHPDAGFPVMRFLEPVPDGEHIINEPDVGINGLTGEAEAAELAAIRDAAYDPRHVYVHAWQQDDIVIADNYTLLHTRVPYRRGLPRHLRRVHVLGDPPLRSYVHDQQSATGTDTQRGTA
>NZ_CP023688.1|WP_003980172.1|2667410_2668571_+|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MIDLFQPQAGDAELAAVAAVFADRWLGHGPRSAAFEAAFAAHVGVRPEHVLFLNSGTAGLFLATELLGLRPGDEVILPSPSFVAAANAVVRAGGRPVFCDVDARTLNPSAEDIEAAVTPRTKAVVVLHYGGYPGDIARIAARCRAAGRTLIEDCACSVASRADGRAVGTFGDLAMWSFDAAKVLTTGDGGMLYVRDAELAVRARRLAYHGLVQPSGLGHARVSSRWWELDVPEPGRRELGNDLTAAIGTVQLDRLPAFLARRSEIVELYDRELAGCDALRLPPPLPAGHTSSYFFYWVQMAAGLRDRVAAALLRDGIYTTFRYAPLHKVPAFGTGGPALPGAERAAAETLCLPLHPGLGDRDVRRVAAALRGAVAAEGRPVLTREG
>NZ_CP023688.1|WP_003980173.1|2668574_2669708_+|DUF1205-domain-containing-protein
MRVLVTTSHGAGHVFPPIALAHALRAAGHDVLFAVPGASCAHVARAGLHAFDSSPTADTEEIFGRLLAERGMTFDRFRTDSPEAVTLAAELFARTSEATVERTVEVATAWRPDLVLYTELQGAGPLVAALLGVPAVEHTISCHHFRQISSRFGPWLAAVYRQYGLDGPPPPPAATIDTRPPSIATYDLGGWPMRALPYTTGAMLPPWLLERPARPRVAVTLGTLRPQLSGVGELRTVVRAAGAVDAEFVLALGDAGPAELGPLPANVRAEGWLPLTALLATCTAMIHHGGNGTTLAGLGAGVRHLVLPGGADDYEVARILRARGVAMVSSPEAVDADLLRHLLTDDALLAAAAEVRDETAALPSPAAIVPRLEKLAG
>NZ_CP023688.1|WP_003980174.1|2669727_2670954_-|methyltransferase-domain-containing-protein
MTGTACRVCAAPLRTFLDLGDHPLSSAFLTPAEALDGAGDTVRYRLAAGQCERCALVQLTGDVPYERRPHQGYPYHSSGSAVIREHFRAAGLHLLRTELRGARGALAVEIGRTDGVVLRTLADAGVRPLAFEPSGRCGYGAARVRPDFLTAASAREAVAAEGRARVVYAANTVCDIADLPGLFAGLDELLTADGAFVFEDPYLGEIVRRTAFDQFYDEHRWYFTATSVRALAERYGFRLTGVERLPVHGGQLRYVLTRAGRRRPAPEVAEVLAEEEARGLTAPATLDAFAGRVERVRGDLVALLEALRAAGRTVAGYGATAKSCTVATYCGLGPYLVPYVCDSTPAKQGRVTPGAHIPVRPPAAFAAPYPDYALLFAWNHADEIMAKEQAFRAAGGRWILYVPEVRVV
>NZ_CP023688.1|WP_050498902.1|2670953_2672300_-|NDP-hexose-2,3-dehydratase
MAASVSTAVPAPVAGRVVDGALGRWFAEAGERTYTRARRIPLDALEGWHTDAHTGDLVHDRGSFFSVGGLDVTAPDGPVPRWAQPVLHQPETGILGLLVKDFGGVPHYLMQAKPEPGNAGGLQLAPTVQATRSNFTRAHGGLSVPYLRHFRSPSPRALIADVRQSEQGAWFYRKRNRNMIVRTTEDVPVLPGHRWMTLPQIHGLLAAGDVVNMDARSVLACLPPRRGPAGRPRHTGREILRWLTDVRSRPGLRTRTVPLRGLPGWHRTGHAIRHDDGRFFEIIAVEVRAGGREVRRWTQPMLRPCGTGVIAFLHTRIDGVPHVLVHAAAEPGSVDAAELTATVCCTPQNYAGLPPAARPRFLDEVQHAPPDRVLFDALLSEEGGRFHHALNRYRIVAVDGPRAYEAAGDYRWVTERQLYALLCHSHYVTVQARTLLTCLRSLSGSEAA

Crispr_ID: NZ_CP023688_4

• CRISPR_ID: NZ_CP023688_4
• CRISPR_location: 2817945-2818032
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP023688_4

Consensus_repeat	Method
TGTCCTCAAACGCCGGACGGGCT	CRISPRCasFinder

spacers of NZ_CP023688_4

>4.1|2817968|42|NZ_CP023688|CRISPRCasFinder
TGATTTCGCTTGGCTGCGGGTCGTCAGGGCTGACGCTTCCTG

CRISPR arrays and Neighbor proteins around NZ_CP023688_4

CRISPR arrays

The CRISPR arrays of NZ_CP023688_4

>merge|NZ_CP023688|4|2817945-2818032|CRISPRCasFinder
TGTCCTCAAACGCCGGACGGGCTTGATTTCGCTTGGCTGCGGGTCGTCAGGGCTGACGCTTCCTGTGTCCTCAAACGCCGGACGGGCT

>NZ_CP023688|4|4|2817945-2818032|CRISPRCasFinder
TGTCCTCAAACGCCGGACGGGCT	TGATTTCGCTTGGCTGCGGGTCGTCAGGGCTGACGCTTCCTG
TGTCCTCAAACGCCGGACGGGCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_030179106.1|2810529_2810736_-|hypothetical-protein	unknown	unknown	gnl|CDD|379386
NZ_CP023688.1|WP_030179102.1|2810789_2812373_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP023688.1|WP_003985227.1|2827448_2828108_+|hypothetical-protein	unknown	unknown	gnl|CDD|99749
NZ_CP023688.1|WP_003985224.1|2824159_2825200_-|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl|CDD|179579
NZ_CP023688.1|WP_073447656.1|2805683_2806262_+|ATP/GTP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_CP023688.1|WP_003985222.1|2821497_2822547_-|agmatine-deiminase-family-protein	unknown	unknown	gnl|CDD|377332
NZ_CP023688.1|WP_003986424.1|2806323_2808078_-|dihydroxyacetone-kinase-family-protein	unknown	unknown	gnl|CDD|237723
NZ_CP023688.1|WP_003985223.1|2822769_2823855_-|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|237363
NZ_CP023688.1|WP_003985229.1|2829916_2830843_-|proline-dehydrogenase	unknown	unknown	gnl|CDD|223580
NZ_CP023688.1|WP_003985218.1|2816012_2817623_-|citramalate-synthase	unknown	unknown	gnl|CDD|237068
NZ_CP023688.1|WP_003986422.1|2805091_2805703_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NZ_CP023688.1|WP_003986426.1|2809618_2810281_-|DUF4360-domain-containing-protein	unknown	unknown	gnl|CDD|372992
NZ_CP023688.1|WP_003985228.1|2828176_2829808_-|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143441
NZ_CP023688.1|WP_030179091.1|2831107_2832436_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
NZ_CP023688.1|WP_030179098.1|2820850_2821480_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|132427
NZ_CP023688.1|WP_003985217.1|2815297_2815924_+|YceI-family-protein	unknown	unknown	gnl|CDD|377274
NZ_CP023688.1|WP_030179095.1|2825329_2826895_+|phosphoesterase	unknown	unknown	gnl|CDD|277318
NZ_CP023688.1|WP_078575497.1|2808322_2809615_+|MFS-transporter	unknown	unknown	gnl|CDD|340895
NZ_CP023688.1|WP_003985220.1|2819456_2820680_-|hypothetical-protein	unknown	unknown	gnl|CDD|223893
NZ_CP023688.1|WP_003985216.1|2812633_2815078_-|polysaccharide-lyase-8-family-protein	unknown	unknown	gnl|CDD|238517

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_030179106.1|2810529_2810736_-|hypothetical-protein	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	3.02931e-08
NZ_CP023688.1|WP_030179102.1|2810789_2812373_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP023688.1|WP_003985227.1|2827448_2828108_+|hypothetical-protein	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	3.92782e-14
NZ_CP023688.1|WP_003985224.1|2824159_2825200_-|3-isopropylmalate-dehydrogenase	gnl|CDD|179579	PRK03437, PRK03437, 3-isopropylmalate dehydrogenase; Provisional.	0
NZ_CP023688.1|WP_073447656.1|2805683_2806262_+|ATP/GTP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	2.76601e-46
NZ_CP023688.1|WP_003985222.1|2821497_2822547_-|agmatine-deiminase-family-protein	gnl|CDD|377332	pfam04371, PAD_porph, Porphyromonas-type peptidyl-arginine deiminase. Peptidyl-arginine deiminase (PAD) enzymes catalyze the deimination of the guanidino group from carboxy-terminal arginine residues of various peptides to produce ammonia. PAD from Porphyromonas gingivalis (PPAD) appears to be evolutionarily unrelated to mammalian PAD (pfam03068), which is a metalloenzyme. PPAD is thought to belong to the same superfamily as aminotransferase and arginine deiminase, and to form an alpha/beta propeller structure. This family has previously been named PPADH (Porphyromonas peptidyl-arginine deiminase homologs). The predicted catalytic residues in PPAD are Asp130, Asp187, His236, Asp238 and Cys351. These are absolutely conserved with the exception of Asp187 which is absent in two family members. PPAD is also able to catalyze the deimination of free L-arginine, but has primarily peptidyl-arginine specificity. It may have a FMN cofactor.	5.40482e-152
NZ_CP023688.1|WP_003986424.1|2806323_2808078_-|dihydroxyacetone-kinase-family-protein	gnl|CDD|237723	PRK14479, PRK14479, dihydroxyacetone kinase; Provisional.	0
NZ_CP023688.1|WP_003985223.1|2822769_2823855_-|branched-chain-amino-acid-aminotransferase	gnl|CDD|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	0
NZ_CP023688.1|WP_003985229.1|2829916_2830843_-|proline-dehydrogenase	gnl|CDD|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	1.25053e-60
NZ_CP023688.1|WP_003985218.1|2816012_2817623_-|citramalate-synthase	gnl|CDD|237068	PRK12344, PRK12344, putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional.	0
NZ_CP023688.1|WP_003986422.1|2805091_2805703_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	8.72271e-43
NZ_CP023688.1|WP_003986426.1|2809618_2810281_-|DUF4360-domain-containing-protein	gnl|CDD|372992	pfam14273, DUF4360, Domain of unknown function (DUF4360). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 200 and 228 amino acids in length. There is a conserved GCP sequence motif near the N-terminus.	1.15886e-85
NZ_CP023688.1|WP_003985228.1|2828176_2829808_-|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl|CDD|143441	cd07123, ALDH_F4-17_P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17. Delta(1)-pyrroline-5-carboxylate dehydrogenase (EC=1.5.1.12 ), families 4 and 17: a proline catabolic enzyme of the aldehyde dehydrogenase (ALDH) protein superfamily. Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH), also known as ALDH4A1 in humans, is a mitochondrial homodimer involved in proline degradation and catalyzes the NAD + -dependent conversion of P5C to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes. Also included in this CD is the Aldh17 Drosophila melanogaster (Q9VUC0) P5CDH and similar sequences.	0
NZ_CP023688.1|WP_030179091.1|2831107_2832436_+|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	9.86275e-19
NZ_CP023688.1|WP_030179098.1|2820850_2821480_-|TetR-family-transcriptional-regulator	gnl|CDD|132427	TIGR03384, betaine_BetI, transcriptional repressor BetI. BetI is a DNA-binding transcriptional repressor of the bet (betaine) regulon. In sequence, it is related to TetR (pfam00440). Choline, through BetI, induces the expression of the betaine biosynthesis genes betA and betB by derepression. The choline porter gene betT is also part of this regulon in Escherichia coli. Note that a different transcriptional regulator, ArcA, controls the expression of bet regulon genes in response to oxygen, as BetA is an oxygen-dependent enzyme. [Regulatory functions, DNA interactions].	1.5639e-17
NZ_CP023688.1|WP_003985217.1|2815297_2815924_+|YceI-family-protein	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	7.6294e-59
NZ_CP023688.1|WP_030179095.1|2825329_2826895_+|phosphoesterase	gnl|CDD|277318	cd00839, MPP_PAPs, purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain. Purple acid phosphatases (PAPs) belong to a diverse family of binuclear metallohydrolases that have been identified and characterized in plants, animals, and fungi. PAPs contain a binuclear metal center and their characteristic pink or purple color derives from a charge-transfer transition between a tyrosine residue and a chromophoric ferric ion within the binuclear center. PAPs catalyze the hydrolysis of a wide range of activated phosphoric acid mono- and di-esters and anhydrides. PAPs are distinguished from the other phosphatases by their insensitivity to L-(+) tartrate inhibition and are therefore also known as tartrate resistant acid phosphatases (TRAPs). While only a few copies of PAP-like genes are present in mammalian and fungal genomes, multiple copies are present in plant genomes. PAPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	3.14901e-37
NZ_CP023688.1|WP_078575497.1|2808322_2809615_+|MFS-transporter	gnl|CDD|340895	cd17337, MFS_CsbX, CsbX family of the Major Facilitator Superfamily of transporters. The CsbX family is composed of Bacillus subtilis CsbX protein (also named alpha-ketoglutarate permease), Klebsiella pneumoniae D-arabinitol transporter (DalT), and similar proteins. The csbX gene is a sigmaB-controlled gene that is expressed during the stationary phase of cell growth. DalT is a pentose-specific ion symporter for D-arabinitol uptake. Most members of this family remain uncharacterized. The CsbX family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
NZ_CP023688.1|WP_003985220.1|2819456_2820680_-|hypothetical-protein	gnl|CDD|223893	COG0823, TolB, Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion].	5.92601e-12
NZ_CP023688.1|WP_003985216.1|2812633_2815078_-|polysaccharide-lyase-8-family-protein	gnl|CDD|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0

Protein sequences

>NZ_CP023688.1|WP_003985218.1|2816012_2817623_-|citramalate-synthase
MTDVPEPSLSDAFHVFDTTLRDGAQREGINLTVADKLTIARHLDDYGVGFIEGGWPGANPRDTEFFQRARAEIDFKHAQLVAFGATRKAGVRVEDDPQVTALLESGAPVVTLVAKSHVRHVELALRTTPEENLAMVRDTVAYLRAQGRRVFLDCEHFFDGYALDPAYAKEVVRTASEAGADVVVLCDTNGGMLPAQVSAVVRTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTANGYGERVGNSNLFPVVAALELKYGRRVLPPGKLAETTRISHAVAEVVNLTPSTHQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPALVGNSMRMLVSDMAGRASIELKGKELGFDLSGDRELVGRVVARVKERELAGYTYEAADASFELLLREEVEGRPRRYFEVESWRAIVEDRPDGTHANEATVKLWAKGERLVATAEGNGPVHALDRALRVALERIYPQLAGLELVDYKVRILEGRLGTGSTTRVLVSTSDGQGEWSTVGVAENVIAASWQALDDAYAYGLLRAGVEPQE
>NZ_CP023688.1|WP_003985217.1|2815297_2815924_+|YceI-family-protein
MALFTRKRATATATDAARTTAVLDADPALARLTGDYTIDPAHSRIGFTVRHAMVTNVRGAFGTHEGTLHLDGADPARSTASVDVTIASVDTGIADRDAHLRGSDFFDAEAFPLMTFRSTAAERVGDATYRVTGDLTIKDVTRPLTIDLEYQGTATDVYGAERVGFEGSAEILRSDWGLTWNAALETGGVMVSDKVKLTFDISAVKAAA
>NZ_CP023688.1|WP_003985216.1|2812633_2815078_-|polysaccharide-lyase-8-family-protein
MPPYPLWSRRGFLGFSGAGALGLALAPALTGPSAVAHAADGDPYEVLRRRWLGIQLGTGYDPAAEPYAARLKETGELARGFRTAMRPAAGSLWPDSPFDPPAGITRSYGRLATMARAYLQPGTGLTGDTGLAADLVRGLDHVHDTVYHSGTTRYGNWWEWQIGSPRLLLDTVAMLYEQLGQERRERYLAAVDHFVPDAMLGDYTGTSTGANRVDLCRVVALRGILGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGFVLLDGLGRLFLLLGGSDWAVTDPKRQIIFDSVEHAYAPLLHNGLMMDSVNGRAISRGYQRTDERRVMRSDHFHGHALVAAVALLAEAATPQERERWQAMVRGWIRRDTSYPVLADRQYEVADLARLKTLADDGGPVAPEPVAHRLFPAMDRAVHRRPGWAAGLAMASDRITYYENGNGENPRGWHTGAGMLYWWGHDFGGGQYTDAFWPTVDPYRLPGTTVSTKRLADNEGGGWGEPKPAARWVGGTTDGEFAAVGQDVRGLSSTLRAKKSWFFAADCVVCLGAGITSRDGVPAETVVDNRNLGPDGAPVLTVDGVRRSAEPGRRLSFPRARWIHLAGHGGYVFPRLPGGADQVPYALRDTRTGAWSDINTGGSPEPFTRRYLTLWLDHGTDPADAAYAYLLMPGAGPRALAARAADRRWLTVLANTGERQAVAVPSLGLTAANFWQAGSAGGLTVSAPASVLLRERPAHAAQGRHGGRTASLCVAEPPRTGKPFEVVWDRPVRAVLAADPSVTVLAITPALRLRVTPGTACTTHTCTVAPR
>NZ_CP023688.1|WP_030179102.1|2810789_2812373_-|acyl-CoA-carboxylase-subunit-beta
MTTVEDVPAEANDARGRVAELHAIREQARRGPSERATEAQHAKGKLTARERIELLLDEGSFREVEPLRRHRATGFGLEAKKPYTDGVITGWGLVHGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIFQRNTKASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVRAVTGEEITQNGLGGADVHAETSGVCHFAYDDEQTCLEEVRFLLSLLPQNNREQPPSVACEDPADRSGDALLDLVPADGNRPYDMRAVIEELVDDGEFLEVHERWATNIIVALARLDGEVVGLIANQPQSLAGVLDIEASEKAARFVQMCDAFNIPIVTLLDVPGFLPGVDQEHGGIIRHGAKLLYAYCNATVPRISVVLRKAYGGAYIVMDSQSIGADLTYAWPTNEIAVMGAEGAANVIFRKQIAEADDPEAMRARMVKEYKSELMHPYYAAERGLVDDVIDPAETREVLIRSLEMLRNKHADLPARKHGNPPQ
>NZ_CP023688.1|WP_030179106.1|2810529_2810736_-|hypothetical-protein
MTTPVQTSPIRVEKGDASEEELAALTAVLLARAAHRPAAVPGRRRATSARWRRLERQHGFQGAGSWQR
>NZ_CP023688.1|WP_003986426.1|2809618_2810281_-|DUF4360-domain-containing-protein
MFRTLGAGAAAASLLILAGAASPASAQASRIGDAPPDGKITINVATVNGSGCRPGSAAVAVAPDNTAFTVTYSEYLAQAGKDSRPTDSRKNCQIALNVQVPQGFTYAIARADYRGYAQLAPGAIGLQQAGYYFQGSAQTDRKSHRFTGPYDANWQSSDDTEIDALVYAPCGEKRYFNINTELRVDAKGSDPKLTSFMAMDSTDGSINTKYHFAWKQCPKP
>NZ_CP023688.1|WP_078575497.1|2808322_2809615_+|MFS-transporter
MVLGYLGVLLFMVGDGVESGFIAPYMAGHGAGTEVHASYVITAYGVTVMLASWLSGALSDLWGPRRVMQLGLAVWVVFDVLFLVLALGPGNYPLMLVFYGLRGFGYPLFAFGFLVWITATAPAARMGTAVGWFYVAFTGGLPTLGSLVAGATNPWFGQFGTLWVALGIIVLGGVCCLLGVRERTGFARLAPPEVRPVQSLMSSLSIAWTHPKVAVGCVVRVINTAPEFGFLVFLPTFFGEELGFGQGRWLTLLAVIYGTNVLCNLLFGAIGDRIGWRRTIATFGGLGCAVTTLTLYFVPKAVGGHYWVAIAVGMLYGITLAGFVPISALIPALAPDNKGGAMALLNLGAGGAAFVGPAIVSVLLGPFGPAGVVIVFAALYVLSAGLTLYLKLPEPTAGQGGDGDTVAPAVAAAPAPPYAEAGPGGGARLP
>NZ_CP023688.1|WP_003986424.1|2806323_2808078_-|dihydroxyacetone-kinase-family-protein
MTTTPAAGPGHDPGTFREDWLEGLADAYARTVRRVPDTYGVVGRHAPRPGKVAVVIGGGSGHYPAFAGLVGPGLADAAAVGDVFASPSAEQVYRTARAADGGAGVLFSYGNYAGDVMHFGLAARRLAAEGVDVRTVLVTDDVASGPPPVEGQPVDPSRDRRGVAGDFFVFKVAGAAAERGDDLAGVARLAARANAMTRTFGAAFAGCTLPGANEPLFTVDAGTTELGMGIHGEPGLRTTRHLTASELADALVDNLLRELPEPPAGGDGRVAVLLNGLGRTKYEEMFVVYRQVNRRLRAAGLHPHRPEVGEFVTSFDMAGVSLSVMLLDDELAELYDAPCDTPAFRSVPGRHDDQRPAESVPAASAAPVRTTPATDLPATAALQAALDLIAANEDELGRLDAVAGDGDHGIGIVRGLRAAVAAARASEPGPAADPRSAGAALLAAGLALADASGGASGALYGTLLAETGAVLAKADTYSTALLADAAEAAQRAVSDLGGAQVGDKTMLDALDPFRTELHARAAEPLPGAWKAAAQSATRAASATAGLTPSRGRAARMGTLGHGHPDAGAVSLSLLVTAVGDYLNG
>NZ_CP023688.1|WP_073447656.1|2805683_2806262_+|ATP/GTP-binding-protein
MDFASSSGAARSTTSAKIVVAGGFGVGKTTFVGAVSEINPLRTEAVMTSASAGIDDLTHAPDKTTTTVAMDFGRITLDQDLILYLFGTPGQDRFWFMWDDLVRGAIGAVVLVDTRRLADCFPAVDYFENSGLPFVIALNGFDGHQPYTPDEVREALQIGPDAPIITTDARHRSEAKSALITLVEHALMARLR
>NZ_CP023688.1|WP_003986422.1|2805091_2805703_+|DUF742-domain-containing-protein
MATPPSGYPYGSGQQSGPQGEHRHNPFNFPSAPSRRQQQPPQPQQPYQQRPYDSRQPYEPSPYEQPRAPRVQPVPPRQRRNGPSAPTGGAHNPLVRPYAMTGGRTRPRYQLAIEALVSTTADPARLQGQLPEHQRICHLCREIKSVAEISALLSIPLGVARILVADLAEAGLVAIHQPGGDETAGGQPDVTLLERVLSGLRKL
>NZ_CP023688.1|WP_003985220.1|2819456_2820680_-|hypothetical-protein
MTGAVAVAVLVGAVAAGGPPAAAGGQGPRTERVNTAPDGSEAVGGGSYNAAISADGRYVAFDSEADNLVPGDDNDGALVRDVFLRDRRTGTTRRLNAPLGHGNADLATISADGRYVAFNAETGGRYHVYVYEIRTGRLERADLGMDTGYDGGESPALSADGRYVAFVGRQSAVPPEKEEMGRIYVRDRRTGTTRRASRVPAEEGRAFDSPRISADGSRVVYRERSRRGGGPGGDRDWADIHLADLRTGEQRQIDTTADGLPATSGSTDPLISADGRTVAFNSAAKNIVPVPDEARSYVFVRNTRTGAIRRVDGINGNQYAEADAIGPDGRRLLLHSYGVEYGLYVKDLKTGQDTLVSPGTDGKPRAATAGPDGMTADGRKAVFESHLDDLVAGDTNHETDVFLRHTR
>NZ_CP023688.1|WP_030179098.1|2820850_2821480_-|TetR-family-transcriptional-regulator
MPGPVRRPRRRLTQPREQVLAAAMATIAEAGLERLTMAGLGREVGMSSGHILYYFGTKDELLLQTLQWSEEQLGARRRAALAQRVPVRERLDALVQLYLPEGRRDPRWTLWLEVWNRSQNADDGARERQLDLELAWHRDLVALLAEGASKGELRTVDADRFATRTRALLDGFGTHLVVGLPGLDREQVLRHVAEFLDEALAPAGAPNVP
>NZ_CP023688.1|WP_003985222.1|2821497_2822547_-|agmatine-deiminase-family-protein
MTTPAADGFRMPAEWAPHERTWMAWPGVNATFGEEGGEELERARRAWAAVARAVRRFEPVTVVAGPGQADGARLLLGAGIDVVERALDDAWMRDIGPAFLVGGRGQLGAVDWVFNGWGEQDWACWERDAEIGGYVGGLAGARTYRSSLVNEGGGLHVDGEGTVLLTETVQLDPGRNPGRTREEVEAEIHACLGTTKAIWLPRGLTADYGRFGTRGHVDIVAAFARPGVVVAHTQPDPAHPDHAVCAEIVKLLRASTDARGRRLEVVEVPAPTVVEADGEPVDYSYINHYLCNGGVVLCAFGDPRDEEAAAIFRRLFPERAVVQADARTIFAAGGGIHCITQQQPKVGTV
>NZ_CP023688.1|WP_003985223.1|2822769_2823855_-|branched-chain-amino-acid-aminotransferase
MTTPTIELKPSAHPLSDAEREKILASPGFGRYFTDHMVTIKWTEGRGWHDAQLVPYAPLSMDPANMTLHYAQTIFEGLKAYRQPDGTVATFRPDANARRFQASARRLGMPELPVETFIEACDALVRQDKNWVPASGEESLYLRPFMIASEVGLGVRPANEYLFIVIASPAGAYFTGGVKPVSVWLSQEYVRAVRGGTGAAKTGGNYAASLVAQAQAAQHGCDQVVWLDAIERRWIEEMGGMNLYFVYGNKIVTPELSGSLLPGITRDSLLKIATDLGYEAAEGRISVEDWKAATEDGSLTEVFACGTAAVITPVGSVKSEAASWTVGDGKPGEVTMKLRKALLDLQTGATPDSHGWMHPLG
>NZ_CP023688.1|WP_003985224.1|2824159_2825200_-|3-isopropylmalate-dehydrogenase
MSRSIRLAVIPGDGIGQEVVAQGLKVLGAVLPQDVKLETKEYDLGARRWHATGETLPDADLESLKEHDAILLGAIGDPSVPSGVLERGLLLKLRFAFDHYVNLRPSKLFPNTATPLAGRPDIDFVVVREGTEGPYTGNGGSLRTGTPHEVATEVSLNTAYGVERVVRDAYARAAARPRKKLTLVHKNNVLVHAGHMWKKIFDKVGEEFPEVTTDYLHVDAATIFFVTQPERFDVIVTDNLFGDILTDLAAAVTGGIGLAASGNINPTGAFPSMFEPVHGSAPDIAGTGKADPTATVLSVALLLRHLGYEAEAARIEGAVAADLEARGTAPRTTGEIGDALASRVAG
>NZ_CP023688.1|WP_030179095.1|2825329_2826895_+|phosphoesterase
MDTPRVGIPEPLAGRLSMPEQHEYLRTKLTRRGLLRTSAVTAGAVAGGGLLAAPAQAASPTLLSSPATGAVHGSLVAPFGRHLAFGADPRHQMRVSWQVPFAVKRPFLRVGLRPWDLSRKIQAEVRDLHTPSLSKKLPAVDQYYLHAALDGLRPGTTYYYGVGHDGFDPADARHFGTLGTFRTAPARAERFVFTAFGDQGVSYHALANDQLILGQNPSFHLHAGDICYADPDGSGTDHDTYDARQWDQFLAQTESVAKTVPWMVTTGNHDMEAWYSPNGYGGQNARWTLPGNGPDAESAPGVYSFTYGNVAVVALDANDVSYEIPANLGVTGGRQTKWLDRRLGELRATRGIDFIVVFFHHCAFSTTNSHASEGGVRDAWLPLFEKHQVDLVVNGHNHVYERTDAIKGGRVSKKVPIGETVDSTREGIVYVTAGGAGKSLYDFPVPDSYEGHVKDLDHVDTYHWAKGREKVKETVQWSRVRYTGYSFIAVEVLPGHRPRMKVTALAESGESVDRFEVTRRR
>NZ_CP023688.1|WP_003985227.1|2827448_2828108_+|hypothetical-protein
MTALAHETPWGFAPEPSGQEVPRPDLDEVLWQAWEAMELPEGFHAEIIEGFIEVSPTGCYAHSQIANKLRRAADRYLADGPYAGHQDTNVVHDRKVWIPDVIIALEDFEAQDVIEHGVGVKASAVEVAVEVVSPGHNSITRDRVRKRRAYARAGIPVYVLVDDHDLRGIVTVFTSPMPDKGDYAAEHRVPYGTDITIPEGPAKGFVIDETITGPPRGDR
>NZ_CP023688.1|WP_003985228.1|2828176_2829808_-|L-glutamate-gamma-semialdehyde-dehydrogenase
MDAVTHVPAPYNEPVHGYAPGSPERARLEAKLKELAENPIELPMTINGEKRMGGGERFDVVQPHNHKAVIGTYANATRQDAQDAIDAALAAAPAWRAMSFDDRAAILLKAADLLSGPWRETIAASTMLGQSKTAQQAEIDAPCELVDFWRFNVHFARELLQEQPPIQPNGVWNRLDHRPLEGFVYAITPFNFTAIAGNLPTAPALMGNVVVWKPSPTQTHSAILLMQLLEEAGLPKGVINLVTGDGKEVSEVALPHPELAGVHFTGSTATFQYLWKAVGENITNYRSYPRLVGETGGKDFIVAHPTADPAILKTAITRGAFEYQGQKCSAASRAYIARSLWEGGFKDDLVAEVEGLTMGDVTDLSNFIGAVIDDRSFAKNKAAIDRAKQDPTCEIVAGGTYDDSVGYFVRPTVIACSDPENEVFKTEYFGPIIAVHVYEDADFDAMLEQMESASAYALTGAVLAQDRQVLVEASEKLRFAAGNFYLNDRPTGSIVGQQPFGGGRASGTNDKAGSKFNLIRWMSPRAIKETMVAPTDYRYPHMG
>NZ_CP023688.1|WP_003985229.1|2829916_2830843_-|proline-dehydrogenase
MLGPVLLAAARSDSIRRIVSAAPVTRPVVDRFVAGEELDASMAAVRSLADRGMEVTLDHLGEDITDPAEALRNRDAYLRLTAALKDLGLGERAEMSVKLSAFGQALPGGHDLALKNVTPVVEAAAEAGTTVTLDMEDHTTVDSTLAILGELRARFPQTGAVVQSYLFRTEEDCHALAWEGSRVRLVKGAYKEPATVAFQDKREVDKAYVRCLKILMAGKGYPMIGSHDPRMVAIGQELARRFGRKPAEYEFQMLYGIREAEQQRLVAEGHRMRVYIPYGTDWYGYFMRRLAERPANLVFFLRSLATKG
>NZ_CP023688.1|WP_030179091.1|2831107_2832436_+|PucR-family-transcriptional-regulator
MRGDYQQLVDEISAALGAPATLEDRDFGLIAFGAHEGDDDLVMDPVRTRSILQRRSTAAVRAWFEAFGIARATTALRIPPDPAAGVFKGRICLPVRHRGIVHGYVWLLDDGHLTDLELGGGGTPPDPRIEQAMESAAGIGALLAAEARAGAELGDLLRALLLSRPGERSSAAAALRDGLRSAPDAPLMVVAVTPWDVPEADQAPLPNLPGLLAACTLPAANASANGSTNGAEAPRPAPSAAPSAPAARRATPAPPPRATADAPSLAALVRLRSPSSLAAAHTVAEHLLRSPRAGGGLAPSGAGSPTLPVAAGLGTPVRELAGLPTTWHEALAAARAARAEPRLGPVAEWAAIGSYRLLTGLPSAEPDSTVRPLLAPAHSELARTAEVFLDCAGQAGRAAQALGIHRQTLYYRLGRVEKLTGLDLDEGGDRLLLHMALKTARL

Crispr_ID: NZ_CP023688_5

• CRISPR_ID: NZ_CP023688_5
• CRISPR_location: 4479372-4479473
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP023688_5

Consensus_repeat	Method
CTTGTTGTCGCTACAAGCGACAACAAGC	CRISPRCasFinder

spacers of NZ_CP023688_5

>5.1|4479400|46|NZ_CP023688|CRISPRCasFinder
ACACACCCCCTTCCACACTCCCTTAGGGCCTGTGACCCCCTCTTTC

CRISPR arrays and Neighbor proteins around NZ_CP023688_5

CRISPR arrays

The CRISPR arrays of NZ_CP023688_5

>merge|NZ_CP023688|5|4479372-4479473|CRISPRCasFinder
CTTGTTGTCGCTACAAGCGACAACAAGCACACACCCCCTTCCACACTCCCTTAGGGCCTGTGACCCCCTCTTTCCTTGTTGTCGCTACAAGCGACAACAAGC

>NZ_CP023688|5|5|4479372-4479473|CRISPRCasFinder
CTTGTTGTCGCTACAAGCGACAACAAGC	ACACACCCCCTTCCACACTCCCTTAGGGCCTGTGACCCCCTCTTTC
CTTGTTGTCGCTACAAGCGACAACAAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_003986238.1|4484911_4486159_+|DUF3631-domain-containing-protein	unknown	unknown	gnl|CDD|372031
NZ_CP023688.1|WP_003986246.1|4480788_4481235_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|236092
NZ_CP023688.1|WP_003983516.1|4470425_4471133_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NZ_CP023688.1|WP_003986248.1|4479795_4480263_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003986245.1|4481401_4481803_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983515.1|4471129_4471651_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003986239.1|4483824_4484739_+|bifunctional-DNA-primase/polymerase	unknown	unknown	gnl|CDD|378140
NZ_CP023688.1|WP_003986250.1|4477160_4479356_+|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NZ_CP023688.1|WP_003986247.1|4480271_4480769_+|hypothetical-protein	unknown	unknown	gnl|CDD|212140
NZ_CP023688.1|WP_139679693.1|4483531_4483828_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983514.1|4471662_4472913_+|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_CP023688.1|WP_003983510.1|4473965_4474262_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983512.1|4473328_4473661_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_050498948.1|4474561_4477168_+|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_CP023688.1|WP_003983509.1|4474275_4474488_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983511.1|4473744_4473969_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003986244.1|4481889_4482306_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_030185237.1|4482354_4483365_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003986249.1|4479567_4479762_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983513.1|4472912_4473296_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_003986238.1|4484911_4486159_+|DUF3631-domain-containing-protein	gnl|CDD|372031	pfam12307, DUF3631, Protein of unknown function (DUF3631). This protein is found in bacteria. Proteins in this family are typically between 180 to 701 amino acids in length.	6.78126e-80
NZ_CP023688.1|WP_003986246.1|4480788_4481235_+|single-stranded-DNA-binding-protein	gnl|CDD|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	5.03406e-58
NZ_CP023688.1|WP_003983514.1|4471662_4472913_+|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	3.55297e-11
NZ_CP023688.1|WP_003983516.1|4470425_4471133_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.73874e-37
NZ_CP023688.1|WP_050498948.1|4474561_4477168_+|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.90944e-09
NZ_CP023688.1|WP_003986239.1|4483824_4484739_+|bifunctional-DNA-primase/polymerase	gnl|CDD|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	5.976e-43
NZ_CP023688.1|WP_003986250.1|4477160_4479356_+|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	7.20504e-09
NZ_CP023688.1|WP_003986247.1|4480271_4480769_+|hypothetical-protein	gnl|CDD|212140	cd11533, NTP-PPase_Af0060_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in uncharacterized protein from Archaeoglobus fulgidus (Af0060) and its bacterial homologs. This family includes an uncharacterized protein from Archaeoglobus fulgidus (Af0060) and its homologs from bacteria. Although its biological role remains unclear, Af0060 shows high sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, members in this family consist of a single MazG-like domain that contains a well conserved divalent ion-binding motif EXX[E/D].	1.73686e-19

Protein sequences

>NZ_CP023688.1|WP_003986250.1|4477160_4479356_+|hypothetical-protein
MFELDWQGRHTLNTGAATAVTSALAVSSLTYVSGVDPLWDAGIAAAGALGSVLAGARSGHLPATLTYRAGLWAGAGAWSWWAAADGPPWSWPCLAALAGGAAFGRLTWNAIGRHESAEKLRRRKAAWDAQEAARQERHDAWGEQWKQRLARITKLEGCRIVAIQPWAANTGYTVEVELPGGATWNQLKRFEEALGSDLRLPEGCGVEVAGGRRKGTAIIRVATVNVIEQTIPFPADLSPTSIDDEFAIGLHKDGTYAKGSLAFQCGLGIGDTGSGKTNTLNVINAQLVRTVDALVWHIDTTGAGLSLPWLTSWAIDGTHQRPVIDWTAPTLDEARALLTMAIQIIEARKRRYQQVMRQANDTKLPVSPEIPAIIIVVDETADLPRDIKGMIETVMNTGRAVRVRVKVSSLRATTDSVPVAVRKRAKWRWGMYVTDPEELAYLFSGYQKVDPSDAPWPGCGFNAYNSTKPRPCKAFQLTPQRMDRIAAAVSARRPVLDKISCEVPHGRYYPSRWARVLPRLYEGEQLHAVTRPYTAVPVVPVPTAAPQSGPAPASGAVPGGPGAGIRPGSPEWNRLFPRRGDATTPAAPEEKPAAPADPPDGRLRLVVNNTDRPQNPPEAPPEPPAPAHSDPAPAQKPEPPRPPEQAKPTSAEPQPTAQDAAMRLVLDAGPDGTGPSRMEADLKAMGYSTHRTTISGWLRLWAAAAEVFQMGSGTQTYYVHRSYVSGRPPSA
>NZ_CP023688.1|WP_050498948.1|4474561_4477168_+|hypothetical-protein
MPEIITPAEPVEEISTPTGPNPPAPDPEPPPTLDLPAPGPDPEPAPDPDAGDAGDEAEDDEEVEPQPVGLPAVPLLANAINLSTVGVCSSLNAVGPIAAIAAGGVAAAGVGALGLATVRSARSAQQRRAEAATTTRAGRTGGTGTSNSSGRGRDRVRSGAAGGAGSGNRGGPGGRRGAAGGGGAARGRSGGRFGSGGGGGPAGARVNRRFGGGGGGGRGLFGRGPSSAGANGASRGGGRTGAASGGFGGRKSDRAAGSGGFLPSRRGTGRGASGGNPGTGTAGSGGRGKNRAGRFDAAAGHRSSGVSSLGRGRGFGRGGRSGSGFGSGSGFGARGGGRGQGWFSGRGNGGGRRGAGGFFGGRGTGRHGFGASGTGKHRGGLGSGRGAGWFKPGHKGRAAGAGRLRGAGRATVKAALGRVSRARQAAGQWLRRWGGRLAAWLRRWRSRAGTWAKAKLTRTWQATGGMRRRNLARLRRWRGQAGTWAKAKLTRAWQVTRLWRRRNLAKLRHLLRLAAAVFFATVAALAVMPPALFVGAVSNVPAALSKRFRFTNHGMPWPGRVFRKVWQGLASASRRRLFSQLSGMATPITGNRGHVGHLCDDPGADTSAPAANETTAERGGHVSVFATSAEEVANTYAAYDPPAMAAVAAEYKGLPDAIRNINGAVMALAENSAVYYPMDPAMAEGVAQVAQVLEATAAYADEIEPTFSQVHDLDIMRLENPRTNEHWWNVGGIDGDGALWAKPSVLATAAEEVSGVYEQWSPEAYADAATNPAMIVGAEYEGVPIGLEHLAQAVTYLATRSAECYPVDPCIAEMVSDVVHGLRKAVSAAMELQPAFRRLHSEEIDHNENPRTNEHMWNTPREGGTQRV
>NZ_CP023688.1|WP_003983509.1|4474275_4474488_+|hypothetical-protein
MSVLKQIFTPRPSLRQIRTAPDDLVLEADEYLRQAVSCEDTGDYAAMTAYAAVASAKVTLAAYLRDADHN
>NZ_CP023688.1|WP_003983510.1|4473965_4474262_+|hypothetical-protein
MKRHRLVLPVAVAVGAVYAVAIGWRLASYHVPLAMLAACAGALFMTAFTLVLRIAEARSTVVHRCRMEGCTFMVQVRHVDAVENRRWQEIAAAHPHRF
>NZ_CP023688.1|WP_003983511.1|4473744_4473969_+|hypothetical-protein
MSCTEGTGTHFFILTVESPGYAMCTQTGTFTPRPGSTREEAFNRIYAQVVRGKPELARPNVVFFSLDRNDLEAS
>NZ_CP023688.1|WP_003983512.1|4473328_4473661_+|hypothetical-protein
MTEHPALTVASQARAIRALAVLADRFAILPSTSFTVGTVCGPDGIEEGIHIDLHACAADFEAWRAALGIDPCGIEYSELSRCHCLRAYTAYEGVPVQLTGYLPYPVMTAA
>NZ_CP023688.1|WP_003983513.1|4472912_4473296_+|hypothetical-protein
MSPAFGKCWDPSGTRWGVPTYPWRYAPSGLATRRQLRARGLRPGGQPVAAQVMRQCRYGSGVAVAYLYEIKRAKPVRPMTAGRRAALAAAMRARRTCPQCRQDAGYCIPRSLGTCVPCAYPDAPHAA
>NZ_CP023688.1|WP_003983514.1|4471662_4472913_+|hypothetical-protein
MTSAADVEAADRTLTIGSWTITIGAIVYSVLTVTPLMAGHTAPGWVWTAPILPLVVDSAVVIVVRLDAALARLHAQAARDGATPRRSVWPFLLRWLTGLMTLVLNVGDSALRGDLVGVGVHIPAPLLLIVNAEAALAYRRAIAAALVRIEREQRERQEREQAARQERERLAREERERERERRERLAREEREQAERLERERREHEAAEQRQAREHAAALERERLASQERRAEAERQEAARIREEERTERLAREEREREERRREQAAHQAREQARIEREQRERQERERLVRERSHTADAQPAKITMNTAAEAVNTPAPAPVNTSVRTAEAAREHPAAAVHAAAPAAAMPGMNSAVNTGPKPVNTAKLSEDEALEAVRQSLADGLTVREAADRTGWSVGWVSARYRDLRAAQQPTAGAA
>NZ_CP023688.1|WP_003983515.1|4471129_4471651_+|hypothetical-protein
MIRIVTAARLAGLRADLDSADERVRQLLGTLDENWARYLRSVRELSEEHQAAEWDAQVAAEKAAELHQSNEQMRQAFTAALLVIARQQHHIGELEQHLAAARTAPSWLYLLRKYGEPHSLHPTAAAAKEHAATCGASRTGWTSSDLPAAEVAWRVEAVAVVPEQAAERVAGAA
>NZ_CP023688.1|WP_003983516.1|4470425_4471133_+|GGDEF-domain-containing-protein
MTVPALERFRERAQHDPDVSWLLNFARSAVQAGRYQSQMIQRLSAELEQARHDPLTGLLTRAGFELYAPRTLELGPCVVLLLDLDGLKRLNDRHGHDAGDAAIRAAGAAFDDPLGLDPSVVAGRLGGDEFAAVVHLPDVAVLPWLLRGLYDNITAPFAHRGQSLTVGVSIGACLTADLPAVSLPLALRLADEAMYEAKRSGGGWRVAAGPTPTRRTVNGRRHGRRGTALEGTTTS
>NZ_CP023688.1|WP_003986249.1|4479567_4479762_+|hypothetical-protein
MALSISAAVLFAILTLVLLRARYVGPGPAIVVFLCGFFAAGTGAYRPIHNLCETLAGALTSLAG
>NZ_CP023688.1|WP_003986248.1|4479795_4480263_+|hypothetical-protein
MPDPYRITTAPAPYEATGHLAYPPLPVSEIPPGVEVVTLPGGARTLAYTQPTAPPPVVPVGGGGQPIPVWAKTVALLAPTIGFGVAAAGVGISYAAPGVIAVSHALWAAVAFIAAGGIAACSVVRALRRRVPAHITQNITANGLFGRANGTINNP
>NZ_CP023688.1|WP_003986247.1|4480271_4480769_+|hypothetical-protein
MFEIRITCDNTETEQIVNALPAAFVIESIRKAPARDQAKTRLYLAADHQPDHADTAQPWAHAKTVKAWLDDRNGRSPEETALRLLKITEEAGEAAQAYIGVRGQNPRKGITHNADDVAAELCDVILSAMVALHDFTGYPARLLADVAAHRGQRLTALTTAASERA
>NZ_CP023688.1|WP_003986246.1|4480788_4481235_+|single-stranded-DNA-binding-protein
MSFGETPVTIIGNLTADPELKYTTGGQALARFTVASTPRTFDREANQWKDGTSTFFRCATWRALAEHVAESLTKGSRVVLSGRIRQHNWQTEQGENRSMLAVEVDEIGASLRFTTVTIEGKRTNGTAPADDPWNTAGNPAKTDEEPPF
>NZ_CP023688.1|WP_003986245.1|4481401_4481803_+|hypothetical-protein
MNRILRGPDGRHWEEAFDRIVFDEEARQWVYGLTAAVQDPDTGRWAADSHGQRITVTGVPDRAGYTEVSADPLHEPCIAHLYRLVAEVTADFEQQTGAPHPRAAALAHALEDLAMRTEQLRRRPRNPPPRRGR
>NZ_CP023688.1|WP_003986244.1|4481889_4482306_+|hypothetical-protein
MFEIRVICEPTDVAKVSSDLTLAFGLTKEIRDYAARDGRRRRLYTEATHRTAPPVLCSVCSEGVRWVGGRDGWWVHARMDTPDHEATPVYWQDGDRLMEAIAAAVRAYCRTDANGLIRATAQDIAAVAASVARLLPGS
>NZ_CP023688.1|WP_030185237.1|4482354_4483365_-|hypothetical-protein
MPGLVTTREAIAAVYGCGTFQGIEPADGAGMVFVYSDPSAGAEYGYTFDGRAEDDEFGPLYLYTGAGAKGDQKPSGRNSSLLTHAEKGRELHLFVAHGKVRGSGAMRQRYVGQMVLDAVQPYEQRWAPGADGVLRRVLVFRLRPVPGATLDEANPIEPATQDTLIELPEPPKASQPPAKPVKVPQQTQAKDKQTEQHATAQTTANVTGGKREVIRREGQLVTAFEAHLKSLGHTVKSFQITVKGERGTLVPDLYDATDNALYEAKGKSRREDVRMAIGQLLDYRRHIGAPPGLRLVVLLPSHPSDDVRDLLTTEGIHLVVQTKAGFDGFPLPAASV
>NZ_CP023688.1|WP_139679693.1|4483531_4483828_+|hypothetical-protein
MTQPAPAPRASNEPTLKPAALRLLREIARADTGQGVVFMSAPCGRWRLDGTAYVVADRTFHPLDAAGYVDVGNGRTDPVRITHAGRAHLGALDARAAA
>NZ_CP023688.1|WP_003986239.1|4483824_4484739_+|bifunctional-DNA-primase/polymerase
MSAPLTMDLPQVPLLAAALAAADRGWHVHPLRPGAKTPALHGEERCPRTGECAGGHRKWEQRATTDPTRIERCWTHAPYNVGIATGPAGLLVVDLDMPKDKDEKGAPDGANCFLALCERAGQPWPTTYTVRSARGGQHLYFAAPDGVRLHNTAGKLGALIDTRAWGGYVVAAGSTTATGDYHVVADAPVADLPAWLLAALTPPPRARGPVTLPSPGRAGAYAQAALRNETDSVRHAPEGTRNRTLVRAARALGRLVASGDLPHAVVEEALNGAGEAAGLTERECRPAVTSALNWSISHNGGTAA
>NZ_CP023688.1|WP_003986238.1|4484911_4486159_+|DUF3631-domain-containing-protein
MNDPAQHAPSPIDGAALLDEVERFHRRFNIFPREAAYVAVTLWDAHAHLVDCGDNTARLAFLSPEPGSGKSRALEIVEALVPRPLATVNASANALFRVVTGEEGRPTILFDEIDTIFSPKAGGNEDLRGFLNSGYRRGASSLRCVGEGANQSAVPFPSFCAVAMAGLGSLPDTILTRSVIIRMRKRAPNEHIEPYRQRTNGKEGHALRDRLAAWADQVRAQVTDAWPELPEGISDRPADVWEPLLAVAEAAGGTWPERARAACVELVAAAKDGEPASLGVQLLTDLRDRVFCGADRMPTAEILRKLHNLEDSPWGDMDGRHLTPRSLAKMLKEYVTGANEPIRTRPIRTTSGTPRGYYAEDLADAWMRYCPPSSPRSATYATSATPQVNSMIDVADTEHVADTSATPPPVLSRTA

Crispr_ID: NZ_CP023688_6

• CRISPR_ID: NZ_CP023688_6
• CRISPR_location: 6139293-6139406
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP023688_6

Consensus_repeat	Method
GGACCCCCCTGAGGCCCCGGACC	CRISPRCasFinder

spacers of NZ_CP023688_6

>6.1|6139316|14|NZ_CP023688|CRISPRCasFinder
CACCCGTCTCGCCG
>6.2|6139353|31|NZ_CP023688|CRISPRCasFinder
CCCCTGGGGCCCCGGACCCCCCTGGGGCCCC

CRISPR arrays and Neighbor proteins around NZ_CP023688_6

CRISPR arrays

The CRISPR arrays of NZ_CP023688_6

>merge|NZ_CP023688|6|6139293-6139406|CRISPRCasFinder
GAAGCCGCCCGGAGCCCCGGAACCACCCGTCTCGCCGGGACCCCCCTGAGGCCCCGGACCCCCCTGGGGCCCCGGACCCCCCTGGGGCCCCGGACCCCCCTGGGGCCCCGGACC

>NZ_CP023688|6|6|6139293-6139406|CRISPRCasFinder
GAAGCCGCCCGGAGCCCCGGAAC	CACCCGTCTCGCCG
GGACCCCCCTGAGGCCCCGGACC	CCCCTGGGGCCCCGGACCCCCCTGGGGCCCC
GGACCCCCCTGGGGCCCCGGACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_030179684.1|6139643_6141026_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|375997
NZ_CP023688.1|WP_030179688.1|6143039_6145943_-|protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP023688.1|WP_030179678.1|6135079_6135820_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_078575602.1|6129746_6130469_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|239942
NZ_CP023688.1|WP_003982425.1|6154187_6155177_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP023688.1|WP_003982422.1|6150823_6151804_-|ATPase	unknown	unknown	gnl|CDD|225518
NZ_CP023688.1|WP_030179695.1|6151950_6153204_-|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NZ_CP023688.1|WP_003980086.1|6132963_6134628_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_CP023688.1|WP_043978479.1|6148650_6149964_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_063727318.1|6127829_6129557_+|ATP-binding-protein	unknown	unknown	gnl|CDD|206743
NZ_CP023688.1|WP_100246486.1|6132628_6132829_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_043979695.1|6134672_6135083_+|acyl-CoA-thioesterase	unknown	unknown	gnl|CDD|223894
NZ_CP023688.1|WP_030179692.1|6147634_6148627_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP023688.1|WP_003987357.1|6141271_6143038_-|magnesium-or-manganese-dependent-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NZ_CP023688.1|WP_003987371.1|6135962_6136367_-|globin	unknown	unknown	gnl|CDD|381280
NZ_CP023688.1|WP_003987372.1|6136441_6137482_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|275041
NZ_CP023688.1|WP_003982424.1|6153272_6154181_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP023688.1|WP_003980090.1|6125199_6127107_+|GTPase-domain-containing-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_030179671.1|6130808_6132215_+|TQXA-domain-containing-protein	unknown	unknown	gnl|CDD|369823
NZ_CP023688.1|WP_003982419.1|6145939_6147283_-|hypothetical-protein	unknown	unknown	gnl|CDD|235175

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_030179684.1|6139643_6141026_-|VWA-domain-containing-protein	gnl|CDD|375997	pfam18571, VWA_3_C, von Willebrand factor type A C-terminal domain. This is the C-terminal domain of von Willebrand factor type A pfam13768.	1.94672e-18
NZ_CP023688.1|WP_030179688.1|6143039_6145943_-|protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	1.94e-86
NZ_CP023688.1|WP_003980086.1|6132963_6134628_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP023688.1|WP_003982419.1|6145939_6147283_-|hypothetical-protein	gnl|CDD|235175	PRK03918, PRK03918, DNA double-strand break repair ATPase Rad50.	0.000518754
NZ_CP023688.1|WP_003982422.1|6150823_6151804_-|ATPase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	1.25386e-21
NZ_CP023688.1|WP_030179695.1|6151950_6153204_-|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP023688.1|WP_003982425.1|6154187_6155177_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.39071e-69
NZ_CP023688.1|WP_003982424.1|6153272_6154181_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.00085e-84
NZ_CP023688.1|WP_063727318.1|6127829_6129557_+|ATP-binding-protein	gnl|CDD|206743	cd11383, YfjP, YfjP GTPase. The Era (E. coli Ras-like protein)-like YfjP subfamily includes several uncharacterized bacterial GTPases that are similar to Era. They generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain.	6.0396e-35
NZ_CP023688.1|WP_043979695.1|6134672_6135083_+|acyl-CoA-thioesterase	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	5.07896e-27
NZ_CP023688.1|WP_030179692.1|6147634_6148627_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.41596e-92
NZ_CP023688.1|WP_003987357.1|6141271_6143038_-|magnesium-or-manganese-dependent-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	2.1205e-40
NZ_CP023688.1|WP_003987371.1|6135962_6136367_-|globin	gnl|CDD|381280	cd14771, TrHb2_Mt-trHbO-like_O, Truncated hemoglobins, group 2 (O); Mycobacterium tuberculosis hemoglobin O like. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P). This group includes a Mycobacterium tuberculosis TrHb2, Mt-trHbO, encoded by the Mycobacterium tuberculosis glbO gene, which is expressed throughout the Mycobacterium growth phase. It also includes a TrHb2 from the thermophilic Thermobifida fusca ( Tf-trHb) which has a high thermostability and at the optimal growth temperature for Thermobifida fusca (between 55 and 60 degrees C ), it is capable of efficient O2 binding and release. Tf-trHb shares a relatively slow rate of oxygen binding with Mt-trHbO.	3.10308e-67
NZ_CP023688.1|WP_003987372.1|6136441_6137482_+|methyltransferase-domain-containing-protein	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	2.17277e-78
NZ_CP023688.1|WP_030179671.1|6130808_6132215_+|TQXA-domain-containing-protein	gnl|CDD|369823	pfam08341, TED, Thioester domain. This domain is found near the N-terminus of a variety of bacterial surface proteins and pili. This domain contains an unusual covalent ester bond between a conserved cysteine and glutamine residue.	8.59292e-16
NZ_CP023688.1|WP_078575602.1|6129746_6130469_+|single-stranded-DNA-binding-protein	gnl|CDD|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	4.92145e-24

Protein sequences

>NZ_CP023688.1|WP_003987372.1|6136441_6137482_+|methyltransferase-domain-containing-protein
MSGTEPGPRSDREPTAAARAELVRQIRAGGHLGDPRWRAAFEEVPRHLFVPYFFVATARGYQRLSGSDHDPDRRARWLEGVYTDTALATYMRDGELVSSSSQPSLMAMMLEDLRVGEREGTGSGCRVLEVGTGTGYNAALMAHRLGTDRVTTVDLDEEITGPARDRLAAAGYRPAVVTGDGALGCPERAPYDRIIATCALPSVPTAWIEQCTAGALVLAPLATGLIALRVTEPEAVRAEGRFLATPAYFVPLRTPVRTPTGTEPAPAGGRRRAPRDALPREALRDERFHFLWSLAAGSLPLDEILGLWRREDRPRRERFGVTVDGSEQYAWLDSPGGPHRWQLGGG
>NZ_CP023688.1|WP_003987371.1|6135962_6136367_-|globin
MNKIPRGTLQEQTFYEQVGGEPTFRRLVHRFYQGVAEDPLLRPMYPEEDLGPAEERLALFLMQYWGGPRTYSDNRGHPRLRMRHVPFKVDRAAHDAWLKHMRDAVDSLELSPEHETQLWNYLTYAAASMINAAD
>NZ_CP023688.1|WP_030179678.1|6135079_6135820_+|hypothetical-protein
MTALRLADAGEAADLAAFLARLIHYDRAAAVRLQAGDGVLAVFGRPPSFEVLAIRTARLAPAAALPGAGLDLTVSAGDLLEGIDEPTDSLTLPAPVTGPPWAGVLPPRGGWQQVPGLPSPQALGRTVALAVAEFRARDEALPPERRTRAERDRIGREIWSRTLGDTHLPLRAAHAAQSLGFLRPVRAEAQAGGHGHPGTGHAAGAALAEPPSLTLLAAGGWLRLRTPYGSVAVRTGGTAALPVMPA
>NZ_CP023688.1|WP_043979695.1|6134672_6135083_+|acyl-CoA-thioesterase
MDAFGHVNNAVFVRYLEEARIDFMWRLAPGEGSASFSGGSVVARHEIDYVRPLVHRHAPVTVESWVTKIGAASMTIAYEIKDEETVYVRASTVVVPYDFAQQRPRRITAEEKSFLREYLDDGAGDDAKQQEGAVAA
>NZ_CP023688.1|WP_003980086.1|6132963_6134628_+|energy-dependent-translational-throttle-protein-EttA
MAEYIYTMRKARKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSTVLKIMAGLEQPSNGDAFLSPGYSVGMLLQEPPLDESKTVLENVQDGARELMDKLKRFNEVAELMATDYSDALMEEMGKLQEDLDHANAWDLDTQLEQAMDALGCPPGDWPVTNLSGGERRRVALCKLLLEAPDLLLLDEPTNHLDAESVQWLEQHLAKYAGTVVAVTHDRYFLDNVAEWILELDRGRAHPYEGNYSTYLDKKQTRLKVEGQKDAKRAKRLKEELEWVRSNAKGRQAKSKARLTRYEEMAAEAEKTRKLDFEEIQIPPGPRLGNVVVEVEHLNKAFGDKVLIDDLSFTLPRNGIVGVIGPNGAGKTTLFKMIQGLEEPDSGSIKVGDTVKISYVDQNRSNIDPKKTLWAVVSDELDYINVGQVEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLLLLDEPTNDLDVETLSSLENALLEFPGCAVVVSHDRWFLDRVATHILAYEGDSKWFWFEGNFESYEKNKVERLGPDAARPHRATYKKLTRG
>NZ_CP023688.1|WP_100246486.1|6132628_6132829_+|hypothetical-protein
MRRRARTGRERKGQGRVGRAGPPPDHGGGADSRSWRPAGPGHGTPSRTPAFAPPLTPPQTPPAPAP
>NZ_CP023688.1|WP_030179671.1|6130808_6132215_+|TQXA-domain-containing-protein
MISVKRRGAARLAAAVLASGLVAAGAIATAGPAAADETTPAHGGASATLDGLKTYGQAVLHANGRDQEIGAGLFEMKVDHGGILQTYCIDISTPTQQMAKYQEVPWSASSLHDNKDAGKIRWILQNSYPQVNDLASLAKKAGAPSLSEKTAAAGTQVAIWRFSDHVKVDAVDPAAEKLADYLEKSAQSLSEPEASLKLDPPAVSGKSGSKLGPVTVHTNAGSVTVSPAAGAPAGVKVVGADGKPVTKASNGTKLFFDVPAGTKDGAMSLTAQAATKVSVGRAFTGSVGRVKSQTMILAGSSESTATATATASWKKQGAAPAVTAEKDCAKGGVDVTATNKGDAPFRFQLSGKEHVIAPGKSETITVPVGEDQAYEITIKGEGGFTKTFTGVLDCKTAGTTPGKPSSQPSPATAGGSSSGTNGTTGGGDLAETGSSSATPVIAGVAVALVVVGGGAVFFLRKKKAGVTQ
>NZ_CP023688.1|WP_078575602.1|6129746_6130469_+|single-stranded-DNA-binding-protein
MYDTMVTLVGNAATAVEHRQTTAGVPMVRFRLATSTRRWDKERCCWVDGDTSFYTVRAWRTLADNVAASVSRGEPLVVHGRMRVWDRELPEDKGGQRRVSVEVDAVAVGHDLTRGTSAWRRVVRPRMEAMVPSAEGWVPEVRAPAPPVPPPPRGSAPQAPLDRVPNEPDWTSPEPAVGPLPGTAVGTEPGEAAGAASGSVGGSSPPPRTGVELGDKSPPDVDGRGVPAAIPASEDAVAGA
>NZ_CP023688.1|WP_063727318.1|6127829_6129557_+|ATP-binding-protein
MQEYGPAPSRKRRSPAERLRPRLDALRELIGLSRTRLDGATLAEAGRVLDAADERYQLSGEHTVVAVAGATGSGKSSLFNALVGADRSDVGARRPTTAEPVACVWSGGWPGAEALLDRLGVSARRRYAPAPGAPALPGLVLLDLPDHDSAAVGHREQVDRMLELVDAVIWVVDPEKYADAVLHERYLRPLAGHAEVTFVVLNQVDRLPGDAAVQVVDDLRRLLDEDGLALGEHGEPGAAVLALSAATGEGVGELRETLRQFVAERGAADRRLTADVDAAAGRLWPAYVTDGRYGLTEPAREEFEDWLAEAVGAGAMGSAAERDWLRHAERACGTPWSRLRLRRRAGARGRGGRPGGGRTSPGRTGASRLWHRDACTEVDAGGDEACATVGGWVPVDGRATARPLVEQAVRTVAGEAAEGLPGPWAQAVREAATRGAEGLPEALDRAAAVSEGALRAGPQVRPRWWSVAGVAQGLLALLQVTGVLWLLAVAVGAVEAGEWFSALLVAGIGTAGGPALSWACGVAGRGPARRYGQEAERRLRTAAAVCGRAAVLEPVAAELLRYREVREQYAVAAGL
>NZ_CP023688.1|WP_003980090.1|6125199_6127107_+|GTPase-domain-containing-protein
MDVQPRLLDVLSALRDRVDAARFPLPLPGAARARRTRSELLDQLDDYVMPRLRSPQAPLLAVIGGSTGAGKSTLVNSLVGRRVSEAGVLRPTTRTPVLVCHPDDRHWFADRRVLPQFTRVRVPVQDGPDAMEAYDGTGPYDETRAYVETHPYDETGPYGGAGPYGGAGPYGGAGPYEGGDSRAGGKSASEGGGGASGPAVARGPGGPTGAGSAVGMVRAAGVAPLRIETDPALPSGLALLDAPDIDSLVARNRELAAELICAADVWVLVTTAARYADAVPWHLLRTAKEYDVTLVTVLDRVPHQIASDISARYAALLTRAGLGDVPRFTIPELPESAGGGSGLLPATAVAALRRWLERHAQDTAVRNAAAARTTAGVLASLRSRMPALAGASAAQHAAAVRLADQVEQAYEEAAARVRREIEQGEVLSGDARAHWRDHELGGRPDELLDALTHGLTSLLRCAVEQADERAADAWRRDPASADAPLAEVAEVAASAARLGVVVRRWRRCLEELAEEGVREARAARGVRTGRGTVRAGERTRAAADPEEAAALLATTLLGGRRARTAGDALAELMGAQAALRLRDRGGRLLETYLQRALDGERERRLAPLESLGVRPEHQAALIAALSLLQKERVTR
>NZ_CP023688.1|WP_030179684.1|6139643_6141026_-|VWA-domain-containing-protein
MANFAKSSVPRFSAEVYQNEYLPEGGREVNAIVTVTATGGGTSGGLPLFAAGTDAGGLGAARGPESAGAARHAGVVIMVDCSGSMDYPPTKMRNAREATAAAIGTVRDGVAFAVVAGTHQAAEVYPGGGRLATADPTTRAQAREALRKLSAGGGTAIGTWLRLADRLLTDADVGIRHGILLTDGRNEHESPEDLRATLEACAGRFTCDARGVGTDWEVKEVTGIAAALLGTADIVADPSGLAADFTRMMEAAMGKEVADVTLRLWTPQGAEVAFVKQVAPSVADLTGRRTESGPRTGDYPTGSWGDESRDYHLCVRVPAAGVGQEMLAARVSLVLPEPGGSAPRTLAQGLVRAVWTDDMAASTTINPQVAHYTGQAELAQVIQQGLDARKSGDADGATAKLGRAVQLASASGNEDTAKLLAKVVDVVDAATGTVRLKAKVTEADEMTLETRSTKTVRVKK
>NZ_CP023688.1|WP_003987357.1|6141271_6143038_-|magnesium-or-manganese-dependent-protein-phosphatase
MGVTGPFRCASCDEPLEPGDNYCGFCGADVVAPAGPDGTGDRPTVPLGDAAGHAAPGAAGPAGSVTLPAGFLMPGAVEAGGSGQAAGPGEVSGPVQAPEPVQAPGPVPPPVPVAAPTPSPAPPYAHSAAYGAQTPAYGSQTPAYGARTAAYGTQPPSAHGAQAGHDGNAPYAPGATAHPNGAAPGPHAPVPPPPPGYAPGGPQADAQSRPPHAEASVPPSSGPAPGPHGDAPDPRVVGYGAGAESSHGPSGDRTPGASGEPVQPPQSPGAPLPTGPASSPEHQTPAQGTRICSVCHAGTVAQDGYCENCGHAQPRERDHMERELPGVAAVSDRGHRHHRNEDFFAISEGTLPDGSPAVLAVVCDGVSSASRPDDASAAASGTAARSLLAALPAGTHPQRAMHDAIIAAAKAVNALAAAPHQPQQHDPYRQQNAPACTFVGAVVGGGLLVIGWVGDSRAYWIPDDRSAAPVRLTEDDSWAAQMVANNLMSEAEAYADDRAHAITGWLGADAYELEPHTASFKPDGPGVVVVCTDGLWNYAEAAEQLAAVLPADAHDRPLHSARTLVAHALAGGGHDNVTVAVVPFPAPR
>NZ_CP023688.1|WP_030179688.1|6143039_6145943_-|protein-kinase
MTEEHTGGAPCQRRDCPGTYEDVGAGELYCDTCGLAPVVSPDGMVGSPPTGVTAGRRGRDWGSGGGGSQGSEGSGGSAGSGGTGPDGSGSTGSASGEGRTSASARSATSRRSVSGRLSRSLSGTSTRSMPVSVRSAGRGSGSGPARGRLGAGLVSVPEVPRPDPRTAVLENPEVPERKRFCSRSDCGAPVGRARGDRPGRTEGFCTKCGHPYSFVPKLRPGDVVHGSYEVVGCLAHGGLGWIYLAIDRAVSDRWVVLKGLLDTGDEEALAAAASERRFLAEIEHSNIVRIYNFVEHLDRTTGSLDGYIVMEYVGGKSLKDIANERRTPHGRRDPLPVEQACAYGIEALEALGHLHSRNLLYCDFKVDNAIQQHDQLKLIDMGAVRRMDDHESAIYGTIGYQAPEVAESGPSVASDLYTVARTLAVLTFDFQGYTNVFVDSLPDPDHIEVFRTYESFYRLLVRATDPDPARRFSSAEEMAEQLTGVLREVVALQTGEQRPSLSTLFGPELRVVDTDVVARAEGDTSLLGARTVAAGRRRAGANGRTAWPFRPGRRSGNAVVGPATGIGAPGEIGGGGPSGVPATVGGTGSGSGSGIVAGPVAAPAGRGTQPAVPAQVAYEITSATGPRAEAGGARGAPVLRPLDIGLAVLALPVPRVDPADPNAGFLAGLLAAAPAELIGALRAAPADTIETRLRKLRAHLEMGDGAAALRELHAIEAEPDRDWAADWRVVWYRGLVALTNDDRETAALSFDAMYDAFPGESAPKLALGICAEVLGQLDNAAEYYRLVWAADHSYVSAAFGLARVRLAEGDRAGAVAALESVPESSIHYTAARIAAIRARLRQRSAKDALLEDLRAAAGEVERLAESGLDAERRERLTTEVLGCALDWVLSGSRGAEQRGRTLPSGAQDPGSGGTAARPGLLGSALDERGLRFGLERSFRLLARLAQRGEERIELVERANRFRPRTWV
>NZ_CP023688.1|WP_003982419.1|6145939_6147283_-|hypothetical-protein
MGVPGSFPGSPGKPHTPVMDREEVDRALGRLAAEYEAIETSLLALQDHAGRRLLEGAELTGVTKDRWAATEQSITVLWAHFDAYTAALTAARELRARRRWPSPDDLAELTELLRGARVTVPGAATTGTAQFGGPARLSEQFSLEELVGRMNTLYAAALDVIVSADAVWSALPARIDLLAAELRRTLSLARSVGVRPGEHPAGDDLERITYELTQLRAQVISDPLAFWSPDADRSAAPGGGRPDTARYDRAARALEDARREIEAVLDVRQDAERRLMQLRDVLSRADRTLTEARQARGEVLAKIAASEVPAVSGPPTALHEQLTTAAEYRRHAQWHRLSPLLDSLEQRAEDELHRARESLTAVTAPLAVRAELRGRLDAYKAKAARHGLAEDPLLTERYDVARRMLWSAPCDLRAAEHAVLRYQQAVAEALLPPDPGPGPADGPQGEA
>NZ_CP023688.1|WP_030179692.1|6147634_6148627_-|glutamate-ABC-transporter-substrate-binding-protein
MTTRARGLRNLRAALAPVAAGVCVMAATAAVLIPVLGGGDGPAPRPAPYGTHSARADAAAADCTPANAAASLRPSPEGGPAVDRIKARGRLIVGVDQNTYRWGYRNPATGDLEGFDITLARAIAEDILGPDPKITFRAIPTSQRIPALQKRTVDLVVRTMTINCARKRQVAFSTAYFQGGQQVLAPINARITGFDDSLKGKRVCTAAGSTGETRLAEERHGARVVTVPNQLDCLVRLQLGEADAVVTDNALAAAQAAQDPTVQLKGKPFTDEPYGVAVNRADTDLVRRVNQVLENYREGGGGSRWMAAYRQWLQADLPGISKAPEPQYSD
>NZ_CP023688.1|WP_043978479.1|6148650_6149964_-|hypothetical-protein
MDQLRAAATTEPGRLRIIGAVLAFLVVAFGAATAWQVTDRAAAARDVVERSQPLSADAADIYRSLADADTTAASGFLAGGKETQATRNRYEADIAMAARLLAKAASNTSGSDTAARQIGKLNSLLPRYTGLVETARTNNRQGLPLGGAYLRYANAQMRGELLPAARELYVAETAHLRADYDSAKAWPWLALSAGVVALGALVWAQRRNYRRTNRVFNHGLLAATTASAVVLLWLAVGHSVARAGLNTSYEDGARSLNVLNEARIDALQARGDENLTLVARGAVVTKDQQDFYEVGYRTGMKDLAGAGRSGAAAADSKLGSALALADDDAGRRPVQEAVETVRQWQARHAEARAADDQGDYDRALAKVIGGGAATGQSFDRVDTQLAGALDHEQRQLRQAADDGRGALTGLVTGAVVLALLGATGAVLGIGRRLSEYR
>NZ_CP023688.1|WP_003982422.1|6150823_6151804_-|ATPase
MLAVDAGNSKTDVALVGADGTVLATARGGGFQPPVVGVARAVGDLAALVEAVRERAGVTGPVSQVSAYLANADLPVEEAELAAEITSYGWARTVTVANDTFALLRTGLSDRGEPVGVAVVCGAGINCVGLGHDGRTARFPSIGRISGDWGGGGHLAEEALWWAARADDGRGEPSALAREVPAHFGLTTMPELIEALHLGRIPRERRFGLTPLLFEVAASGDAVARALVQRQAEEIALLASVALGRLDLLDEPTPLVLGGGVLAARHPLLHDELARLLAERAPKAEPRVVTEPPVLGAALHALDRAGAGAEAYERVREGFGGGGAGG
>NZ_CP023688.1|WP_030179695.1|6151950_6153204_-|6-phospho-beta-glucosidase
MKIAVVGGGSTYTPELIDGFARLRDALPLAELVLIDPAADRLELVGGLARRIFAKQGHPGRISWTSDVDAGVDGADAVLLQLRVGGQAARNQDETWPLECGCVGQETTGAGGLAKALRTVPVVLDIAERIRRRNPDAWIVDFTNPVGIVTRALLSHGHKAVGLCNVAIGFQRKFARLLGVAPERVELEHVGLNHLTWERAVRVDGEDVLPRLITEHGAAIAEDLHMPRSLVERLGVVPSYYLRYYYQHDEVVEELRSKPSRAAEVAAIEKQLLEMYGDPSLDEKPELLGKRGGAFYSEAAVALTSALLGDTGDVQIVNTVNNGTLPFLPDDAVIEVPATMGAGGAKPLPVRPLEPLYSGLIANVTAYEHLALEAALKGGRDRIFEALLAHPLIGQIAYADRLTDELIAHNREHLTWL
>NZ_CP023688.1|WP_003982424.1|6153272_6154181_-|carbohydrate-ABC-transporter-permease
MTTTTLRAGSAPARTGTTDRGPAASRARRKRLLHWIAVHSVAVAAALFFVLPFVFVFLTSVMSDDQAMSGELWPHEWNWSNYATVFATPGFLDWWRNSLMYAGLGTLFTVGSAIPVAYALAKFRFRGRRIAMLLVISTMMLPPQVIVIPMYLVWAQQLHLSGSLWPLIIPMAFGDAYSIFLLRQFLLTIPQEYIESAKVDGCGEVRTLLRIVVPMAKPGIAAVALFQFFYCWNDYFGPQIYAAQNPAAWTLSYGLESFKSAHNVNWNLTMAATLLVMAPVIIVFFFAQKAFVEGVTLTGVKG
>NZ_CP023688.1|WP_003982425.1|6154187_6155177_-|sugar-ABC-transporter-permease
MSLVESPERPAATAPRPKAPALRRKHRGQRLRTLGFLSPWLVGFSVFFGYPLLATVYFSFMHYNQIQQPSFVGLRNWKYVFTQMPLFGPALWNTLWLVVVMVALRVVFGLGIGLLVTKIKSGVGFFRTAFYLPYLAPPVAATVAFVFLLNPGTGPVNEILEALGIPAPGWFNDAAWAKPSLVMLSLWGIGDLMVIFMAALLDVPKEQYEAAELDGAGAWARFRYVTWPSITPIVLFAVVTGVVQTMQYYTQALVAGKLASGVTIGPGTVIQPGYPDHSTLTVPQLVYSLGFQNFNTGAACVLSLVLFVIAMAVTTLLMRKRAGLLPAED

Crispr_ID: NZ_CP023688_7

• CRISPR_ID: NZ_CP023688_7
• CRISPR_location: 6402664-6402850
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP023688_7

Consensus_repeat	Method
GGGCGGCCACGAGAGCGGCGGTAACTTCGCCAACGACCCGCAGCGTGCGTCCGAAG	PILER-CR

spacers of NZ_CP023688_7

>7.1|6402720|10|NZ_CP023688|PILER-CR
TCGGTCAGAA
>7.2|6402786|10|NZ_CP023688|PILER-CR
CCGGTCAGAA

CRISPR arrays and Neighbor proteins around NZ_CP023688_7

CRISPR arrays

The CRISPR arrays of NZ_CP023688_7

>merge|NZ_CP023688|7|6402664-6402850|PILER-CR
GGCGGGCACGAGAGCGGTGGCAACTTCGCCAACGATCCGCAGCGTGCGTCCGAAGTCGGTCAGAAGGGCGGCCACGAGAGCGGCGGTAACTTCGCCAACGACCCGCAGCGTGCGTCCGAGGCCGGTCAGAAGGGCGGCCACGAAAGTGGCGGTAACTTCGCCAACGACCCGCAGCGCGCCTCCGACG

>NZ_CP023688|7|1|6402664-6402850|PILER-CR
GGCGGGCACGAGAGCGGTGGCAACTTCGCCAACGATCCGCAGCGTGCGTCCGAAGT	CGGTCAGAAG
GGCGGCCACGAGAGCGGCGGTAACTTCGCCAACGACCCGCAGCGTGCGTCCGAGGC	CGGTCAGAAG
GGCGGCCACGAAAGTGGCGGTAACTTCGCCAACGACCCGCAGCGCGCCTCCGACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_078627364.1|6405300_6406800_+|enterochelin-esterase	unknown	unknown	gnl|CDD|236695
NZ_CP023688.1|WP_003980704.1|6398921_6399863_+|ketoacyl-ACP-synthase-III	unknown	unknown	gnl|CDD|236475
NZ_CP023688.1|WP_003986550.1|6413148_6413607_+|hypothetical-protein	unknown	unknown	gnl|CDD|226158
NZ_CP023688.1|WP_003980706.1|6397296_6398043_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP023688.1|WP_030183091.1|6408731_6409028_+|divalent-cation-tolerance-protein-CutA	unknown	unknown	gnl|CDD|376987
NZ_CP023688.1|WP_043978518.1|6410097_6410802_-|membrane-protein	unknown	unknown	gnl|CDD|225500
NZ_CP023688.1|WP_003980705.1|6398039_6398723_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP023688.1|WP_003986558.1|6407257_6408043_+|TSUP-family-transporter	unknown	unknown	gnl|CDD|182593
NZ_CP023688.1|WP_003980703.1|6399906_6400353_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003986552.1|6411468_6412479_+|adenosine-deaminase	unknown	unknown	gnl|CDD|236480
NZ_CP023688.1|WP_003980709.1|6395234_6396572_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP023688.1|WP_003980702.1|6400610_6401816_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_043978568.1|6393813_6395097_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224171
NZ_CP023688.1|WP_003980711.1|6391189_6393811_-|nitrite-reductase-large-subunit	unknown	unknown	gnl|CDD|184951
NZ_CP023688.1|WP_003980699.1|6403072_6405064_-|lipoprotein	unknown	unknown	gnl|CDD|371457
NZ_CP023688.1|WP_003980708.1|6396633_6397284_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP023688.1|WP_003986553.1|6410933_6411365_+|gamma-glutamylcyclotransferase	unknown	unknown	gnl|CDD|377602
NZ_CP023688.1|WP_003986551.1|6412575_6413031_+|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NZ_CP023688.1|WP_003986557.1|6408077_6408410_-|hypothetical-protein	unknown	unknown	gnl|CDD|380358
NZ_CP023688.1|WP_003980701.1|6401812_6402439_+|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|213983

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_078627364.1|6405300_6406800_+|enterochelin-esterase	gnl|CDD|236695	PRK10439, PRK10439, enterobactin/ferric enterobactin esterase; Provisional.	4.31447e-85
NZ_CP023688.1|WP_003980704.1|6398921_6399863_+|ketoacyl-ACP-synthase-III	gnl|CDD|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	3.55749e-150
NZ_CP023688.1|WP_003986550.1|6413148_6413607_+|hypothetical-protein	gnl|CDD|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	3.03161e-08
NZ_CP023688.1|WP_003980706.1|6397296_6398043_-|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.68786e-05
NZ_CP023688.1|WP_030183091.1|6408731_6409028_+|divalent-cation-tolerance-protein-CutA	gnl|CDD|376987	pfam03091, CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).	1.19496e-41
NZ_CP023688.1|WP_003980705.1|6398039_6398723_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.50328e-07
NZ_CP023688.1|WP_003986558.1|6407257_6408043_+|TSUP-family-transporter	gnl|CDD|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	7.41032e-37
NZ_CP023688.1|WP_003980711.1|6391189_6393811_-|nitrite-reductase-large-subunit	gnl|CDD|184951	PRK14989, PRK14989, nitrite reductase subunit NirD; Provisional.	0
NZ_CP023688.1|WP_003986552.1|6411468_6412479_+|adenosine-deaminase	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	8.44739e-157
NZ_CP023688.1|WP_003980709.1|6395234_6396572_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.95854e-32
NZ_CP023688.1|WP_043978518.1|6410097_6410802_-|membrane-protein	gnl|CDD|225500	COG2949, SanA, Uncharacterized membrane protein [Function unknown].	1.54678e-54
NZ_CP023688.1|WP_043978568.1|6393813_6395097_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224171	COG1251, NirB, NAD(P)H-nitrite reductase [Energy production and conversion].	5.07392e-102
NZ_CP023688.1|WP_003980699.1|6403072_6405064_-|lipoprotein	gnl|CDD|371457	pfam11308, Glyco_hydro_129, Glycosyl hydrolases related to GH101 family, GH129. This family of bacterial and lower eukaryote glycosyl hydrolases is related to CAZy family GH129,and distantly to GH101, and is made up of sub-families GHL1-GHL3.	3.68126e-110
NZ_CP023688.1|WP_003980708.1|6396633_6397284_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	6.38982e-38
NZ_CP023688.1|WP_003986553.1|6410933_6411365_+|gamma-glutamylcyclotransferase	gnl|CDD|377602	pfam06094, GGACT, Gamma-glutamyl cyclotransferase, AIG2-like. GGACT, gamma-glutamylamine cyclotransferase, is a ubiquitous enzyme found in bacteria, plants, and metazoans from Dictyostelium through to humans. It converts gamma-glutamylamines to free amines and 5-oxoproline.	1.64369e-21
NZ_CP023688.1|WP_003986551.1|6412575_6413031_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.44204e-06
NZ_CP023688.1|WP_003986557.1|6408077_6408410_-|hypothetical-protein	gnl|CDD|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.84233e-14
NZ_CP023688.1|WP_003980701.1|6401812_6402439_+|hemerythrin-domain-containing-protein	gnl|CDD|213983	cd12108, Hr-like, Hemerythrin-like domain. Hemerythrin (Hr) like domains have the same four alpha helix bundle and a similar, but slightly different active site structure than hemerythrin. They are non-heme diiron binding proteins mainly found in bacteria and eukaryotes. Like Hr, they may be involved in oxygen transport or like human FBXL5 (F-box and leucine-rich repeat protein 5), a member of this group, play a role in cellular iron homeostasis.	1.77247e-11

Protein sequences

>NZ_CP023688.1|WP_003980701.1|6401812_6402439_+|hemerythrin-domain-containing-protein
MTPHARTGDGPATPTTDPAADRNPTPETDVVALLMAQHGQIRDLFDEVEQSTGDARRDAFRRLVRMLAVHETAEEEVVHPYVKRAADGGDDIVADRLAEEKTAKQALSALDGMDVEDAAFLPRLLSLRTDVMEHARAEERYEFSQLRRLNDPGRLAAMAKAVKAAEAIAPTHPHPGVESGAANAVLGPMAAVVDRTRDAVRKALDKNG
>NZ_CP023688.1|WP_003980702.1|6400610_6401816_+|hypothetical-protein
MSFNPLEQRGIPLDRQVRNWRELNVTPVDPDHCDPYTRCRIITMNGIEVEAILFSHQLARHCPDMEIKQQLARTRYIEAQQQKAVNWLLPGVSSVLETTIAYEQVAVDLTAWVARMEPDPYLKQAYQFGVLEDFDHLYRYANLYEMIEHRKAESVVDGLTEVMPGRPTPLHHRDPVDNVREPYDRTKTDPLSKLHALTIMSAEQQTMNFYMNTGPTYMEPIARRLYQEIGLIEEEHVTHYESLVDPGETWWEQLVNHEYNECYLYHSFMEQESDPKVKAIWELHLNMELEHLHLACDLMRRHDGREPAEILAPALPNVLTFEPNKGYLRQLIADQLDLTTLGAGYVREAHERFEAMQEALNGGATPPSDEVLAEHDKLIGGDHRLQTEGEHPVADLRGGRS
>NZ_CP023688.1|WP_003980703.1|6399906_6400353_-|hypothetical-protein
MTTAPDLPELTALDEVAALVGRHDDLYVRWSRGPGIDLEAASSRDDLTGIALPGLSANALAVAPWWDGRPVRLWVARRLYDYSHLPREKGSAVRPWLLHGHEAGRGPDNEPLVTQVEPVGWIAPEVMREATEEVARQAGVWGPLRRVR
>NZ_CP023688.1|WP_003980704.1|6398921_6399863_+|ketoacyl-ACP-synthase-III
MPGTRIAALGHHQPSRVLTNDDLAGMVDTSDEWIRRRTGIVTRRIADEESVTDLAAAAAAKALAAAGLQPADIGLVTVATCSAIDRCPSTAAQVAAVLGIPSAVAYDLNNGCAGFCTALATADHAVRAGAARHALVIGAEKMSDVTDWTDRSTCVLLGDGAGAAVVSAADSAHIGPVVWGSDPTRSQAVRLMGDWHPHFEQDGQTVFRWVTTELAPLAREACERAGIGLADLAGVVTHQANLRIIESVVQQLDLPEHVVVARDVIDSGNTSAASVPLALSKLVERRDLPPGGPVLLLSFGGGLSFAGQVVDCP
>NZ_CP023688.1|WP_003980705.1|6398039_6398723_-|TetR/AcrR-family-transcriptional-regulator
MSPRKSAAESRRTRDRIIDRSIAIASVEGLDGLTIGRLATDLGMSKAGVLGHFGTKEALQLASLDGASAIFSRAVWEPAARTAPGLARLRAICEYWITYLEREHGAFPGGCFFTTAAVEFDARVGPIRDAVVRRSTLWRRRLANEIRYAVEAGELPRDTDPDQLVFELIGLYTGLNQAIQLFADPLAQDRTRRALDRLLAPAPRPEAALSSEAAPPSGTAPGSGAAR
>NZ_CP023688.1|WP_003980706.1|6397296_6398043_-|GNAT-family-N-acetyltransferase
MSVADLLRTEIEVIWPTDGRGRFRGPQHMVISVSADGHHQVPAVADHLPDALAADLLASVAKEPAPEGPGLPPPALPRLRHLLEAVVGPVHITSGPSYLIRPDRLRFTPTAPVVPSDTEDPAALTALRCANPGNWDTDEWHDLLDGKLGPWAMALDPADPARVVSICHTPCWTDHGAEAGTWTRPGHRGRGHAATVTAAWSRLQAPTGRHLFYSTSDTNRSSRNVAARLGLAPLGHLWKLSPPASIAL
>NZ_CP023688.1|WP_003980708.1|6396633_6397284_+|response-regulator-transcription-factor
MRVVIAEDSAILRDGLVQLLALRGVEVAAAVGDAESLRAAVAGHRPDAAVVDIRLPPGHTDEGLRAAVAIRRDHPGTGVLIFSQYVETKYATQLLGGGAAGVGYLLKERVVDIGEFVDALERVAAGGTALDPEVVTQFFGAGRRANALDTLTPREREVLAQMAQGRTNQAIAAACTVTERAVEKHIAHIFTKLDLPPSETDHRRVLAVLRYMEAVG
>NZ_CP023688.1|WP_003980709.1|6395234_6396572_+|sensor-histidine-kinase
MPTAASAPRLRHRVLAPFTSRSLAAVLHAVLGLPFALLGMALVVGGLLVSTVLAWTALGPWLMALTVRGAAALGGAQRAMARGLLAMDIEAPARREGGGPLGWRRAVLGDKAGWRAVGCALLAPFTAVAPLLVVLVAYVYGLLFLAHPVLKHVNYFTERGPDGSERHVSLQVGGVEFDSWPRWLLVVATGAVLLLAAPWLLRQAQAPHRFLVRSLLGPDPSAQRIRTLEETRAHAVEDAAATLRRIERDLHDGTQARLVGLGMHLTMIRELIGAGADRDRLLAVVETAQGNAKQAVADLRHLVRGIHPPVLDQGLDAALATLAADSALPVTLTVDAATRRHPSPAVESILYFCAAELLANAVKHSGASGVTMELTSGPDRDPDAAAGSGGELRLLVRDDGRGGAVIGAGSGLTGLRARVRTVDATLTCDSPPGGPTVVTVRVPRA
>NZ_CP023688.1|WP_043978568.1|6393813_6395097_-|NAD(P)/FAD-dependent-oxidoreductase
MVVIGGGMAAARLAQRLGRASADGGPVLTVIGEEPHAPYNRVLLADVLAGRYAQEVITLPAPHSAVRWLGGVRAERIDRERRTVLCDDGQAVPYDRLVLATGSNPVLPPLRGLFPPGRPDLPDGGLPHGVHPFRTLDDCTALAAAAARPGARAVVIGGGLLGVSAARALAERGVPVLLAQQGEHLMERQLDAEAAALLRAHLEALGVEVHTECRVRGLRVEDGAVRGVELADGYAPAADLVVLACGVRPRVGLARAAGLPVDRGIVVDDQLRTADPLIHSIGDCAQHDGLVYGLAGAALEQADQLARILGAEAARYRGTRALTRLTLTGPGSAPRSAGAPLDLAAFGTPSPRPGDDVIHLSDATRGAYRKVIVRGDRLVGGILLGDLGAVGTLARTWEADDPLPPTAPLLHLLTTETATPSRTDGGS
>NZ_CP023688.1|WP_003980711.1|6391189_6393811_-|nitrite-reductase-large-subunit
MAATAVPTLVLIGHGMVGQRFLEALADRGVTGRARVVVLCEEPRPAYDRVQLTSYFSGRAPDDLALADADFMARHGIELHLGDPATAIDRAARTVTARSGLTVTYDTLVLATGSYPFVPPVPGADSAGCFVYRTVEDLLAIEEYAKNCRTGTVVGGGLLGLEAAGALKGLGLRTRIVEFQPRLMAVQVDEGGGSALRRTVEEMGIDVHTGVGGKEIVAGGDGAVRAMELSDGSRVETDLVIFSAGVRPRDRLARDCGLAVGERGGIVVDERCRTGDPAVYAIGECALAADGKVYGLVAPGYEMAETAAAAIAGDPEVSAFTGADTSTKLKLLGVDVASFGDAHGTSPGCLDVVYADSRSGVYKKLVIGADGELLGGVLVGDAESYGLLRPLTGTVPPVAPEQLVLPAGTGAPAGALGPAALPDDAVICNCHNVTKGTIRAAVSEHSCTTVPEVKKCTKAGTGCGSCVKALTTLVNDELTAGGVVVDQGLCGCFPHTRAELYEIVRTRRLTSYAELLDGHGREEARGGDGCETCKPAVASIIASLAPTVGADGYVLDGEQSALQDTNDHFLANLQRNGSYSVVPRIPGGEITPEKLIVIGEVARDFGLYTKITGGQRIDLFGARVDQLPRIWARLVDAGFESGHAYGKALRTVKSCVGQTWCRYGVQDSVRMAIDLELRYRGLRSPHKLKSAVSGCARECAEARGKDFGVIATSNGWNLYVGGNGGATPRHADLLAQDLSDAELIRLIDRFLMFYIRTADRLERTSAWLERIEGGLDHVRDVVVHDSLGLCDELESLMAAHVSAYRDEWADTLADPDRLARFVSFVNAPEAPDPAVRFVPERDQIKPDLPLLSGPTLPVRTLTTSRPLEGTAAR
>NZ_CP023688.1|WP_003980699.1|6403072_6405064_-|lipoprotein
MDFKIASRGSRTRTRVLAASLALTATASVGASGCSSQAVAGPATGRHVDIPVRGGTVTVDTGTLALQARTADGKNLTLSAPSGTALGTPGPVERTGEGARWSYPDKGLTVTAAADHGRLRVSVKADRDGSLTWPVTGTDRATSSVQLPRGEGLDIPVRDTFWNSGKGGLTGDPIDVGGLELPLWGTTLGKGHGVSYLTPTDLGTSLKFRSEGGRLNSSTTHDFTAGDGTRDYTVTFALTDGNPVAPGADYRSWLAEHGQLGSLREKIKQNPANGKLLGAFHAYVWGDARKAAGVEELRKLGVDRMWLGYDAGPDPMDAAAVRAAKKAGYLVGPYDTFANGQDPKTADSPTSKWPGTVYPDFCVRDAKGKPQSGFGNRGCYLSSQAFEQSGAGRGHLADRTRAMTANGADSYFLDVDATGELFRDHDAAHPMTKAGDRTNRLARMRRLAHDKKLVLGSESAQSWANGVLAFNHGGATPVADGLWKFERDRKNWGGYYPENAPTAFFKPVRLPADLAKAMYDPAYRVPLYETALHSSLVNAERWELSYEKLPEQKTGRALLAMLYNIPLNYVLDGASLKKSGPEMAALQKYFAPLHKATGTEKLTSFRRLTADNLVQRTEFGNGKLTVTANFGKIPYAGLPAGCVDAKLRGDRQPRRLCPAKAGG
>NZ_CP023688.1|WP_078627364.1|6405300_6406800_+|enterochelin-esterase
MKTSVGTSTGAVGGTLPGAAAGTATGTAGGTVPGAPSGGPAGTGEAGAVHAAPPRTSRPAPAETVDSPRIVALAASVAGGRDAAVREFWAETEGQGTPLVEPIPWDPEHRAVTFLWRGTEDTRRVLLLVNGLVDRSHLVGSLMRRIHGTDVWHLTYRLRSDHRGSYAIAPDTGGGRIRTAAAPEDGPADDFQARLLPLLAEAGPDPLNPRTVPGRRQGAGSSVFELPDAPPQPWRPWAPAAATAAAARRGLVERHRLTSAALAARRDVWTYVPPGPLPDGGADALVLLDGDMWCGRLGVQALFDRLIRDGVLPPLVVLAPDAVDNATRAREFGGRPAYVNFLAAELLPWAAARLPVTFDPSRTVVAGESLGGLTALYAGLAAPRRFGKVLAQSPSLWWRPGGPGPVDGTDAADGPSWLAERYAGGGPRELRAHLRVGRYEGDMRKRCGELRDTLRGLGHSVAYTEYNGGHDYACWAGGLAEGLVDLLGRADDGAREGGV
>NZ_CP023688.1|WP_003986558.1|6407257_6408043_+|TSUP-family-transporter
MPADITLTTTLLLCVAALAAGWIDAVVGGGGLLLLPALLVGLPHTPAAYVLGTNKSTAVVGTAAAAYTYVRKAPVDLRTAVRIGLAALGGSLGGAFFAAGINSEVLRPLIMAVLVGVLAFVLFRPAFGTAPPPSGPVTRRRVMAAVLVAGLGIGFYDGLIGPGTGAFLVVALAAILHMDLVTSSATAKIVNVCTNVGALAMFAYQGTVLWQLGALLAAFNFVGGTVGARMALKRGAGFVRGVLVVVVVSLLCKLAFDQWVA
>NZ_CP023688.1|WP_003986557.1|6408077_6408410_-|hypothetical-protein
MDDLSSLTRRQLDDARASAHGRSAHLFLQDGPLRQTVIALIEGAALDEHTTPPAASLQVLHGRVRLTGTGDERDLIAGQVVPVPHERHGLKAMQDSAVLLTAVTATKTMN
>NZ_CP023688.1|WP_030183091.1|6408731_6409028_+|divalent-cation-tolerance-protein-CutA
MTTTDSAGKAEALARGAIEARVAACAQIGAPVTSVYRWEHAIETAQEWQVLFKTAADRYAALEAYLLEAHDYDTPEIIATPITRGGAGYLAWVAEETS
>NZ_CP023688.1|WP_043978518.1|6410097_6410802_-|membrane-protein
MTQQTQREGRLRRIRSRVRLPRARRGQRRAFQVTVLACVAALLPATWLNATTGSRVRTVEDVPAAPVAVVFGAGLWDGEPSPYLAHRLDAAARLYERGTVRALLVTGDNSREDYDEPDAMRAYLVAHGVPGNRIVSDYAGFDTWDSCTRARRIFGVDRAVLVSQGFHIRRALALCGAAGLDAYGVGVDDRHDVTWYYGGTREVFAAAKAAVEATVRPDPHFLGPREGGVTAALR
>NZ_CP023688.1|WP_003986553.1|6410933_6411365_+|gamma-glutamylcyclotransferase
MTTEPERLPFFVYGTLRPGRANHARCLRGRTAAEESALVRGVSLYEGPGYPYAVTGPAEAVVHGDLVRPREDVYDAVRAALDRLEGYVPGAPGNLYERVARPAECADGRSVRAWLYVAAEPLAGQLRASGTPVPGGDWKRPPR
>NZ_CP023688.1|WP_003986552.1|6411468_6412479_+|adenosine-deaminase
MPPTTPAPATPFPKAELHLHIEGTLEPGLAFALAERNGVTLPYATEDELRRAYSFSDLQSFLNLYYALMAVLRTEDDFADLTHAYLARAQAQGVRHAEIFFDPQAHTSRGVPIGTVIGGLTRALDTAEERYGITTRLIMCFLRDESAESALATFEAARPYLDRITAVGLDSAEVGHPPSKFKEVYALAREAGLKCVAHAGEEGPPAYVWEALDVLGVDRIDHGVRCLEDPDLVARLVADQVPLTVCPLSNVRLRVIDELADHPLPAMLDAGLLVTVNSDDPAYFGGYADDNFTAVRDALDLDEETLRTLARNSFRASFLDEATRETYLKEVEAHGR
>NZ_CP023688.1|WP_003986551.1|6412575_6413031_+|winged-helix-turn-helix-transcriptional-regulator
MQYSHSDAELAGQPIGYWAWAAHTAAVTHIRTGLARHGLDQPQWWVLNQLVGHADGRDRAEVTDMLKGYLDVGAEGIGAAVDALLGRGLAVADGGRLHITAEGADLHARCAALQKEMRATIHDGISDEEYVRTLKVLQRMIHNVDGKMWHH
>NZ_CP023688.1|WP_003986550.1|6413148_6413607_+|hypothetical-protein
MTADPTADTPGTATDRAPVAEATRSVVRQFLAARPAGDTGRLTGLFADEVDRQLAENPAVPWIRPRHTAAECAAQAEEPAAHTVPEEARASLDAFLADGTDAVVTGHVAGTVRATGGTSEGPFALRLTVENGRITRHHLYENSLSIAEACRP

Crispr_ID: NZ_CP023688_8

• CRISPR_ID: NZ_CP023688_8
• CRISPR_location: 6426760-6426867
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP023688_8

Consensus_repeat	Method
GGTTACTGGTTCGAGTCCAGTCGGGGGAGC	CRISPRCasFinder

spacers of NZ_CP023688_8

>8.1|6426790|48|NZ_CP023688|CRISPRCasFinder
TCGGTCCCCTGTAGCTCAATTGGCAGAGCATTCGGCTGTTAACCGGAG

CRISPR arrays and Neighbor proteins around NZ_CP023688_8

CRISPR arrays

The CRISPR arrays of NZ_CP023688_8

>merge|NZ_CP023688|8|6426760-6426867|CRISPRCasFinder
GGTTACTGGTTCGAGTCCAGTCGGGGGAGCTCGGTCCCCTGTAGCTCAATTGGCAGAGCATTCGGCTGTTAACCGGAGGGTTACTGGTTCGAGTCCAGTCGGGGGAGC

>NZ_CP023688|8|7|6426760-6426867|CRISPRCasFinder
GGTTACTGGTTCGAGTCCAGTCGGGGGAGC	TCGGTCCCCTGTAGCTCAATTGGCAGAGCATTCGGCTGTTAACCGGAG
GGTTACTGGTTCGAGTCCAGTCGGGGGAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_030183116.1|6436813_6437200_+|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP023688.1|WP_003986550.1|6413148_6413607_+|hypothetical-protein	unknown	unknown	gnl|CDD|226158
NZ_CP023688.1|WP_003986863.1|6418580_6419858_+|ferredoxin-reductase	unknown	unknown	gnl|CDD|170080
NZ_CP023688.1|WP_003985195.1|6426127_6426427_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003985206.1|6440074_6442471_+|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|223256
NZ_CP023688.1|WP_030183108.1|6424552_6425992_-|sugar-kinase	unknown	unknown	gnl|CDD|198375
NZ_CP023688.1|WP_003986866.1|6423173_6424370_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|235640
NZ_CP023688.1|WP_031024289.1|6429077_6430262_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NZ_CP023688.1|WP_030183110.1|6427261_6428038_-|cyclase-family-protein	unknown	unknown	gnl|CDD|224790
NZ_CP023688.1|WP_003985205.1|6439006_6440011_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP023688.1|WP_003986864.1|6419958_6420921_+|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|235918
NZ_CP023688.1|WP_078575570.1|6432892_6436696_+|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224446
NZ_CP023688.1|WP_003985200.1|6432387_6432744_-|CdaR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
NZ_CP023688.1|WP_003986862.1|6416920_6418252_+|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|235098
NZ_CP023688.1|WP_003986549.1|6413614_6415774_-|molybdopterin-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|239155
NZ_CP023688.1|WP_050498784.1|6428102_6428906_-|amidinotransferase	unknown	unknown	gnl|CDD|224747
NZ_CP023688.1|WP_030183103.1|6415976_6416924_+|hypothetical-protein	unknown	unknown	gnl|CDD|225049
NZ_CP023688.1|WP_003985204.1|6437845_6438877_-|rod-shape-determining-protein	unknown	unknown	gnl|CDD|237564
NZ_CP023688.1|WP_003986865.1|6421052_6422966_+|DNA-primase	unknown	unknown	gnl|CDD|235551
NZ_CP023688.1|WP_003985203.1|6437192_6437789_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|366010

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP023688.1|WP_003985205.1|6439006_6440011_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	1.1e-54	180.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_030183116.1|6436813_6437200_+|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	2.52573e-33
NZ_CP023688.1|WP_003986550.1|6413148_6413607_+|hypothetical-protein	gnl|CDD|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	3.03161e-08
NZ_CP023688.1|WP_003986863.1|6418580_6419858_+|ferredoxin-reductase	gnl|CDD|170080	PRK09754, PRK09754, phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional.	7.49191e-72
NZ_CP023688.1|WP_003985206.1|6440074_6442471_+|excinuclease-ABC-subunit-UvrA	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP023688.1|WP_030183108.1|6424552_6425992_-|sugar-kinase	gnl|CDD|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	5.52773e-113
NZ_CP023688.1|WP_003986866.1|6423173_6424370_+|RNA-polymerase-sigma-factor	gnl|CDD|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	5.29819e-160
NZ_CP023688.1|WP_031024289.1|6429077_6430262_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.44423e-25
NZ_CP023688.1|WP_030183110.1|6427261_6428038_-|cyclase-family-protein	gnl|CDD|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	9.27586e-41
NZ_CP023688.1|WP_003985205.1|6439006_6440011_-|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	6.19285e-48
NZ_CP023688.1|WP_003986864.1|6419958_6420921_+|pyridoxal-phosphate-dependent-enzyme	gnl|CDD|235918	PRK07048, PRK07048, threo-3-hydroxy-L-aspartate ammonia-lyase.	1.83558e-156
NZ_CP023688.1|WP_078575570.1|6432892_6436696_+|molybdopterin-dependent-oxidoreductase	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	5.7704e-168
NZ_CP023688.1|WP_003985200.1|6432387_6432744_-|CdaR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	1.11181e-19
NZ_CP023688.1|WP_003986862.1|6416920_6418252_+|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|235098	PRK03007, PRK03007, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NZ_CP023688.1|WP_003986549.1|6413614_6415774_-|molybdopterin-oxidoreductase-family-protein	gnl|CDD|239155	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol oxidation via a membrane-anchored tetraheme cytochrome. Members of the MopB_Nitrate-R-NapA CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP023688.1|WP_050498784.1|6428102_6428906_-|amidinotransferase	gnl|CDD|224747	COG1834, COG1834, N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism].	9.40934e-53
NZ_CP023688.1|WP_030183103.1|6415976_6416924_+|hypothetical-protein	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	8.65205e-24
NZ_CP023688.1|WP_003985204.1|6437845_6438877_-|rod-shape-determining-protein	gnl|CDD|237564	PRK13930, PRK13930, rod shape-determining protein MreB; Provisional.	3.21436e-122
NZ_CP023688.1|WP_003986865.1|6421052_6422966_+|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NZ_CP023688.1|WP_003985203.1|6437192_6437789_+|histidine-phosphatase-family-protein	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.44114e-57

Protein sequences

>NZ_CP023688.1|WP_003985195.1|6426127_6426427_-|hypothetical-protein
MRYRLTFMTGLAIGYVLGTKAGRERYEQLRKSARRITQNPAVRNTAESAALGGREVATKAFDKVSEKVGDRMPGPVAARIRSLREQRGGDADDWGTSNT
>NZ_CP023688.1|WP_030183108.1|6424552_6425992_-|sugar-kinase
MGIVAGLDSSSESTRIVVCDADTGAVIRQGYAPHPAEKGHEIDPQAWLMSLGEAAGNGLLEGVQAIGVSAQQHGMLPLDADGALVRAALVGNDKRAQSAAADLTDALGGRAAWTQAVGAVPHAAQPLTKLRWLARNEPANAARVAEVLQPHDWLVWQLLGRPARRTTDRGGASGTGYWSAAAGAYRPDLVELALGHQVRLPEVLGPSGTAGFTPEGLLISAGTGETMAAAFGLGVGAGDAVVSLGASGSVFGIHHEALADSNGTITSFADATGMHLPVVHTSNAVRVLRGTAEMLGTDLTGLSELALKSTPGSYGLVLLPYLEGERTPHLPHTAGSLHGLRRESMKPEHLARAAFEGMLCGLADALDVLRGRGVEVRRVFLLGAAAELGAVQAAAPGLFGAQVVVPQPADYAALGAARQAAWALGAAHGTLAPHEPPRWPAAASQVFEPGEDLPVGQAVRQQYIAVREESYAGAFLSSQ
>NZ_CP023688.1|WP_003986866.1|6423173_6424370_+|RNA-polymerase-sigma-factor
MPESSERGGSGCTEPESPAEPLLMYGTDSGSAADAPGLSAASAAFTLEVAPVQTRTLADAPAAQTATVPQQAEPPAPEILVEEIAPEPPPRPEAGGPSSDLFRQYLREIGRIPLLTAVEEVELARRVEAGLFAEEKLRLAPDLDSQLALDLDKLVVLGRMAKRRLIEANLRLVVSVAKRYVGRGLTMLDLVQEGNLGLIRAVEKFDYARGYKFSTYATWWIRQAMSRALADQARTIRVPVHVVELINRVVRVQRRMLQERGYEPAPEEVAAQLDLPPERVSEVLRLAQEPVSLHAPVGEEDDVALGDLIEDGDAASPVESAAFLLLREHLEAVLSTLGERERKVVQLRYGLVDGRPRTLEEIGRIFGVTRERIRQIESKTLNKLRDHAFADQLRGYLD
>NZ_CP023688.1|WP_003986865.1|6421052_6422966_+|DNA-primase
MAGRINDDDVKAVRDAVPIDAVVSEYLQLRNAGGGNLKGLCPFHDEKSPSFHVSPAKGLYHCFGCQEGGDVVDFIMKLDHLSFAETIERLASQAGITLRYEEGGYAPGRQQGERTRLVEAHKAAAQFYVEQLDSPEAEIGRRFLADRGFDQAAAQHFGVGYSPAGWDHLTRFLRGRGFSDKELILSGLSQDGRRGPIDRFRGRLMWPIRDIAGEVVGFGARKLRDDDNGPKYLNTPETPLYRKSHVLYGIDLAKKEIAKTNRAVVVEGYTDVMACHLAGITTAIATCGTSFGEGHIKILRRLLMDNSGSEVVFTFDGDAAGQKAALRAFEDDQKFAAQTSIAITPGGMDPCDLRLAKGDAAVADLVESRTPLFEFALRQVVARHNLDTTVGRAAALDEAAPIVANIKNSSIQHESAVQLAGMLGILDTQFVVRRVGQLARWARERGRDGQDPSRTGRRAAQQAPEATQPPAGPRGPALNLRSPAHRVERELLKLALQRPDLVSPAFDAYGADEFTAPPYATVRRCIEDAGGVQSAAGDNTYLARVREAAPDDTVRSLVTELAVEPLHTRRDPDEAYAGVQLVAVRLAAVNHRVTEIRGALQRLGPNADPQHLAAVQNELWVLQQYGQALRERGYAAL
>NZ_CP023688.1|WP_003986864.1|6419958_6420921_+|pyridoxal-phosphate-dependent-enzyme
MPEATVTPDDVREAAARLKGVVHRTPVLRSRTLDRLVGAEVHLKCENFQRVGAFKFRGAYHAVSRLAPEQLARGVAAFSSGNHAQAVALAARELGSSAVILMPEDSPRSKRDATEGYGAEIVTYDRYTGDRAALGAQLAADRGLALIPPYDHPHVIAGQGTAALELIEDTGPLDALLTPVGGGGLMAGSALAATALSPGIRMIGVEPEAGDDTRRSLAAGERVRIPVPHTIADGQALSEPGELTFAVNRRLLDSVVLVSDDEIRAAMRLAFERLKIVTEPSGASALAALLAGAVEPLPRRVGVVISGGNIGLDRFLELMG
>NZ_CP023688.1|WP_003986863.1|6418580_6419858_+|ferredoxin-reductase
MVDAHQTFVIVGGGLAGAKAAETLRAEGFTGRVILICDERDHPYERPPLSKGYLLGKEERESVFVHEPAWYAGADIELHLGQPAVHLDRAARTVRLGDGTLIVYDKLLLATGAEPRRLEIPGTGLAGVHHLRRIAHAERLRGVLHSLGRDNGHLVIAGAGWIGLEVAAAARSYGAEVTVVEPEPTPLHSVVGPELGSLFTDLHSEHGVRFHFGARLTEIAGQDGVVLAARTDDGEEHPAHDVLAAIGAAPRTALAEQAGLTLVDPAYGGGVAVDAALRTSDPNIYAAGDVAAFPYSLLAPENGEPAVLRVEHWANALNGGPAAARAMLGQEVTYDRIPYFFSDQYDVGLEYSGYAPPGSYDQVVCRGDVGKREFIAFWLSEGRLLAGMNVNVWDVTDPIQKLIRSGRVLDPNALADPEVALDSLL
>NZ_CP023688.1|WP_003986862.1|6416920_6418252_+|deoxyguanosinetriphosphate-triphosphohydrolase
MTGTRTTAGREAGHNGTGYGPADTERWVPEPDKRPGRTAFQRDRARVLHSAALRRLAGKTQVVTPGTTEHLWDASPRTRLTHSLECAQVGRELGAALGCDPDLVETACLAHDLGHPPFGHNGEQALNEVAAPCGGFEGNAQSLRLLARLEPKRFVPEPDGTDVSVGLNLTRAALDAATKYPWPRGGHPTDPGSPKFGVYEDDLPVFAWFRQGAPEAARSFEAQVMDWADDVAYSVHDVEDGLHAGYLDPNCLLAEPERAEVFAIAAERYAPGADPAELGAALDRLLDQEWWPHGYDGTAVAQARLKDATSQLIGRFCLAAETATRAEWGTGRLTRHRARLVVPPGTRLECAVLKAVAERYVMRRPDQEALRADQRVVIAELAEALIARAPDGLDPQFRALYDRAEAAGDDTARMRALIDQIAALTDASARSLHARLTRPRGTL
>NZ_CP023688.1|WP_030183103.1|6415976_6416924_+|hypothetical-protein
MTASTPPPPPAGPSGTEVPFDSTAQIMTEITTQLGERLGRVRLHGLPRRGPAAPRPAPGAATARQAPPLVAVAHGSRDPRALRTVTALLDRVRALRPGLTVRLGHIELNAPLLPDTLARLNGPAVAVPLLLARGHHVGHDIPAALADAPHLTACLARPLGPHPLLAEALHARLEEAGARRPSAVVLAAAGSRAPESATDTARTARLLSDRLGGVPVLPAYASAPPEGGPPGTPLSVPAALRALAARGHHRPAVASCFTAPGRFAAQCAAAAPGPAAAPLGDHPALARLVLHRYDQALAARSAYDHDPTGAATVAV
>NZ_CP023688.1|WP_003986549.1|6413614_6415774_-|molybdopterin-oxidoreductase-family-protein
MTAATPRTAHAPAAPPQEAHASAPVETHCPYCSLQCGMGLRRAPAGAAGPPAEVVERPAFPVNRGALCGKGRTAAELLAPGARLTEPLVRDTATGRLVPADWETALRRVADGLARTGAAYGKDAVGVFGGGGLTNEKAYALGKFARVVLGTSQIDYNGRFCMSSAAAAHQRAFGLDRGLPFPLADIARTGCVLLVGSNLAETMPPALRYLTELKENGGRLIVVDPRRTRTAEQADLHLAPRPGTDLALALGLLHLVVAEGRTDEEFIAARTSGWPAARAAAMAHWPELVERITGVPVPQLRAAVRLFCEADGSMVLTARGPEQQAKGTDTVGAWINLCLATGRAGRERSGYGCLTGQGNGQGGREHGQKADQLPGYRKLADPAARAHVAGVWGVPPDSLPGPGRSAYELLDALGRDVRALLLMGSNPVVSAPRAAHVEQRIRALDFLAVADVVLSETAALADVVLPVAQWAEETGTTTNLEGRVLLRRRALSPPPGVRTDLEVLNALASHLGWEKGFPADPEEVFDELRRASAGGPADYAGITYRRIATEDGVFWPCADEDHPGTPRLFLDRFATPDGRARFVPVTHRPAAEEPDEAYPVVLTTGRVLAQYQSGAQTRRVPDLNTAAPGPYVEIHPRLARQHGIENGRPVAVTSRRGRAVAPARYSEAIRSDTVFMPFHWPGPGRANTLTNPALDPTSGMPEFKVCAVRVEAVAPEEEA
>NZ_CP023688.1|WP_003986550.1|6413148_6413607_+|hypothetical-protein
MTADPTADTPGTATDRAPVAEATRSVVRQFLAARPAGDTGRLTGLFADEVDRQLAENPAVPWIRPRHTAAECAAQAEEPAAHTVPEEARASLDAFLADGTDAVVTGHVAGTVRATGGTSEGPFALRLTVENGRITRHHLYENSLSIAEACRP
>NZ_CP023688.1|WP_030183110.1|6427261_6428038_-|cyclase-family-protein
MTGVTRSHVVDLTHAFAPGQPHGPQFDDEQRYCGMTIEQDGFDTAYHRIAGAWGTHVDAPAEMVAGGRTIDAIPAGELVLPLIVFDISAEVAADPDRCLTLPDVLQWEQRHGHVPAGCFAALRTDWSRRWPDAAAMHNRDAQGISHTPGWTLEALHHLLDARSVTAIGHETINTDPGMWTTAEPPDGGTGPDSARRLHACEAYVLDHDRYQVEILTNLHSLPPTGAHIVVGVGNAQQSTAFPARVLALLPYDRPADHH
>NZ_CP023688.1|WP_050498784.1|6428102_6428906_-|amidinotransferase
MCRPTYFDVTDSETPWMDPDEPVNTAEAVSQWERLRDRLRGLGHTVEELPARPGLPDMVFSANGATVIDGRVLGARFSYRSRAPETAAHRAWFLSHGVAFHEPEHTNEGEGDYAVTASHLLAGYGFRTPLAAHAEAQEFFGRPVLSLELVDPRYYHLDTALTVLDRAADEIAYHPDAFAPASRAKLRRIFPDALHASASDAAALGLNAVSDGLHVLLPHTAHGLFPALRDRGYQPIGVNVSELTKGGGGVKCCVLELRGLDLHKNTG
>NZ_CP023688.1|WP_031024289.1|6429077_6430262_-|glycosyltransferase-family-4-protein
MPDRRESSHVDTVASRPLRPAAPRTSRRMSITARVYGYPPAHNAGSEWMLHSMLRPLAERGHRVTVWLSHPGTIDRTYDIDGVRVVPFQEGADFAAEAQRADVLLSHFENVPLITGLAKSRQIPVVVICHDNFATSFHNAAGADLVVYNSEWIRRDGEIHYARYPAEFLPRRSIVVRPPVLAEEYRTEPGDCATLVNLNPDKGGELFWQLAAWTPEWHFLGVRGAYGQQVMPPPRLPNCEVLDSVTGKEMRTHVYGRSRVMLMPSLYESWGRVAVEAFASGIPVIAHPTPGLVESLGEAGIFAYRDDLNAWTHALMSLRDPANWERASARARARSDELTKNSDLDEWCAAVEALGEERPRTSLRVRGLGSLVEADAMGGGPEDGIRRTGGERRA
>NZ_CP023688.1|WP_003985200.1|6432387_6432744_-|CdaR-family-transcriptional-regulator
MPHTTPPLPGEGSAPATLERLLAAVPADVRAVFSARTLRPLLPEHDRTGTLLHTLETFLHHDASWSRTAAALHLHVNTVRYRIQRIEHLTGRDLTRLSHRLDLRAALLCRAGAGEGAA
>NZ_CP023688.1|WP_078575570.1|6432892_6436696_+|molybdopterin-dependent-oxidoreductase
MTFRALRRPYGGRACFTRCMDLNTVREVRDARERPEWRPGDAWLGGGTYLFSEPQPGVRRLLDLGRTGWEPLRWRPDGTLEIAATCTIAEVSRFGRGLGRLAGPLFEQCCRAFLASFKIWNTATVGGNVCLALPAAPMVSLAAALDGSCLLLARDGTARRLPVIDLVVGAGRNALAEGELLRSVTLPARALERRTAFRQTSLHGLGRSAALLIGTREPLDGAFTLTITAATVRPVRLRFPALPDAGALRAAIGRAVPDGGWFDDVHGLPEWRRHMTYRMGEEIREELGAQVGGNALVTLAGGSAVVPQATLGPSPSPPARPRPAPFRTETNGASTPFRTAANDAPTPFRTEVNGTPTPTPPRPGQCLRTYLRERGWCGVKKGCDAGDCGACTVHVDGEPVHSCVYPALRADGRKVTTVEGLADPVSGQLHAVQRRFLEAQGFQCGFCTAGFLMTTAALDADLSADLPRAFKGNLCRCTGYRAIEDAVRGVRHTEDAAAGCGVGRNVPAPGAPDVVTGRARYTFDIDLGTAALPGLLHMKLLRSPHAHARITAIDTRAALRVPGVHAVFTHHDAPGRHFSTAQHEHPEDDPSDTRLLDDTVRHVGQRVAAVVADSEAAAEEGCRRVVVTYEVLPAVLDAEEAMRPGAPVVHDKGEWAGIARPGANVAGEVHGETGDVARGFAAADVVYEETFRTQRAQHASLETHGALAYFEPGEKSAGPQERLVVRTSTQVPFLVRRSLCALLDLPPESVRVVAGRVGGAFGGKQELLVEDVVALAALRTGRPVKLEFTREEQFTGATTRHPFTVRVKVGARRDGTLTALQLYVVSDTGAYGNHAGSVLMHGCGDALALYRCPNKKADGFAAYTHTVPAGAFRGYGLGQVVFALESALDELARQLGLDPLAVRERNVVRPGDELETVVGAESDLRIGSYGLDACLEVLRAASASQGAGEPAAPDGWLVGEGSALTMIAAGGPGGHFADARMTLTADGAYELAVGTTESGSGATTAHRQLAAAELGIGEERITVRQADTDAVGHDTGVFGSAGTVVAGRAVVRAARSLAALIRERATRNGPLTDHGPLADHGPLADHDPLTSHGPLTGHGHATGTPRTVAFNAHWFRVAVDPDTGEIRILRSVHAADAGTVINPMQCRGQIEGGVAQALGSALSEDVRLDGRGRVRTAAFREYRLPAFADVPRTEVRCTPTADTIGPAGAKSMSESPFNPVAPALANALRDATGVRFTRLPLTRDRVWRTLAGEASRRPSDGPGNSHG
>NZ_CP023688.1|WP_030183116.1|6436813_6437200_+|thioredoxin
MSTVELTKDNFDDIVSGSDFVLIDFWAEWCGPCKQFGPVFERSSEKNDDLVYAKVDTEAQPELAAAFQIQSIPTLMIVRENIAVFSQPGALPEAALEDVIGQARNLDMDEVRASVEEAQKQDGQAAGE
>NZ_CP023688.1|WP_003985203.1|6437192_6437789_+|histidine-phosphatase-family-protein
MNDLLLIRHGETEWSRSGQHTSWTDLPLTARGEEQARSLRPVLADRKIGAVLSSPLQRARHTAELAGLPAPRVDADLSEWDYGGYEGISTDEIHRTRPDWFLFTDGVAAGPPEHPGESPEQVGARADRVLARIEELLRTADGDVVLVGHGHFQRVLTARRLGLPASAGALFTFETGTVGVLGEEHGRPAVVGWNTRTL
>NZ_CP023688.1|WP_003985204.1|6437845_6438877_-|rod-shape-determining-protein
MTASLAQLHRCSVAVDLGEARTRMYVKNQGVVVNQPTVAAVNIRTGALIAVGDHAEVMDGRTPDHIRVVRPVSGGTVVDIDMAQRLLRNLVDDKLRKAWRRRPTMRAAICLPYGSEPLAQRAAVETLNGIGARRVEMVDTLVAAAVGCDLPVEQPEATMIVVCGAGTTQIAVLSLGSIVAAETVPVGGNAIDHAVVQHLRLHHKLMLPGQSVRPLHLMLSGDGDLVAGPTEVHGRDVVSGLARSVMVETEPVRRAIASPLTGILDGIGSVLRRCPPDLVADLGERGIMLAGGSALIPGLQSMIRQATTMPVHIAERPDTCAVLGLGDMIEGKVEPLHLDPMAT
>NZ_CP023688.1|WP_003985205.1|6439006_6440011_-|YafY-family-transcriptional-regulator
MSDTPARLLKLLTLLQTGRERTGTELADRLGVSPRTVRRDIDRLRGLGYPVDAALGAIGGYRLASGTAMPPLLLDDEEAVAIAVGLHAAAGGTLADVAETSVRALAKLEQVLPARLRDRVTALQEATVPLYGLLTGGGDAPVTDPAVLTALATACRRRERVRFAYAAADGAPSKRHAEPYRLVSADRRWYLVAYDLDRADWRTFRADRIGAPRATGARCVPDRRPPTPDAAAFVAESIVSHRARYRALVTLCTPLEDAARRLPAGTGLLEPLTPGSCLLRTGGDALDWLAYRLGFLGVPFEVHEPPELIAYLRDLGTRLVDASYGTPEPRGQEP
>NZ_CP023688.1|WP_003985206.1|6440074_6442471_+|excinuclease-ABC-subunit-UvrA
MGAEHADRSTSTAGATGTADTTATTGIDCITITGAREHNLKDVDIRIPKGRITVFTGVSGSGKSSVVFDTVAVESQRQLNETYTWYVRNQLPKHERPKADTIERLTPAIVVDQRPVGGGARSTVGTMTDIHAVLRVLFSRCGTPSAGEATAYSFNDPAGMCPECAGLGRTTRIDLDRFLDTGRSLNEGAIRFPPLAVGTAGWQIYATSGLFDPDEPLDRYGPEEWDLLLYGKGFKVKRGERAYNNTYEGLVEHFDRRYVKRGLEALPEKTREMVRAFVKDGTCPRCRGGRLTEAALKSQVAGLTIAEMAALEVTELSAVLRGIDPADDPVGAVIAARAVTALDRLTDIGLGYLSLDRPTDTLSGGEGQRLKTVRHLGSSLTGMTYIFDEPSTGLHPSDVRRLNDLLIRLRDKGNTVLVVEHDRDVIAIADHVVDMGPGAGTQGGEVVFAGTVRGLAAADTPTGRGLRRVTGVKEDPRTPGGWLTVRDVTLHNLKGVDFSVPTGVLTVVTGVAGSGKSTLVSGAFVGAHPEAVVVDQSAIGVSARSTPATYLGVMDAVRTLFARANGVRAGLFSFNSAGACEVCRGRGEIHTDLAYLDPVTTTCEACRGRRFKDEVLGLTLGGRSIADVLEMTGTEAREFFSGAGGAGPVADAAEVLTMVRKLGALVEVGLGYLTLGQSVSSLSGGERQRLKLATRLHRTGSLYVLDEPTTGLHMADVDGLLDLLDRLVDGGNTVLVIEHDLDVVKRADWVVDLGPGGGRRGGEIVFAGTPRELVAARGSATAACLRASLRGTLLDGAL

Crispr_ID: NZ_CP023688_9

• CRISPR_ID: NZ_CP023688_9
• CRISPR_location: 6832531-6832630
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP023688_9

Consensus_repeat	Method
GTGCCTGGTGCCTGAGTCGTCAGT	CRISPRCasFinder

spacers of NZ_CP023688_9

>9.1|6832555|52|NZ_CP023688|CRISPRCasFinder
CGTCAGTTGCGGTGCGGGTGCCTGTGGGCCTGAGTCGTCAGACCCGGGGCGT

CRISPR arrays and Neighbor proteins around NZ_CP023688_9

CRISPR arrays

The CRISPR arrays of NZ_CP023688_9

>merge|NZ_CP023688|9|6832531-6832630|CRISPRCasFinder
GTGGCGGGTGCCTGGTGCCTGAGTCGTCAGTTGCGGTGCGGGTGCCTGTGGGCCTGAGTCGTCAGACCCGGGGCGTGTGCCTGGGGCCTGAGTCGTCAGT

>NZ_CP023688|9|8|6832531-6832630|CRISPRCasFinder
GTGGCGGGTGCCTGGTGCCTGAGT	CGTCAGTTGCGGTGCGGGTGCCTGTGGGCCTGAGTCGTCAGACCCGGGGCGT
GTGCCTGGGGCCTGAGTCGTCAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_003983443.1|6826088_6826580_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP023688.1|WP_030180221.1|6843257_6844721_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983439.1|6820239_6821055_-|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl|CDD|184638
NZ_CP023688.1|WP_030190118.1|6825099_6826050_-|TIGR01777-family-protein	unknown	unknown	gnl|CDD|273800
NZ_CP023688.1|WP_003987033.1|6837146_6838691_-|leucyl-aminopeptidase	unknown	unknown	gnl|CDD|234863
NZ_CP023688.1|WP_086026302.1|6835411_6836818_-|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|235798
NZ_CP023688.1|WP_003982371.1|6846812_6847010_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_030180224.1|6833528_6835358_-|2-oxoglutarate-dehydrogenase,-E2-component,-dihydrolipoamide-succinyltransferase	unknown	unknown	gnl|CDD|200219
NZ_CP023688.1|WP_003987031.1|6839054_6841145_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983446.1|6828450_6829422_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP023688.1|WP_003983440.1|6821416_6822979_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003983441.1|6823063_6824290_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366721
NZ_CP023688.1|WP_003983438.1|6819132_6820083_-|lipoyl-synthase	unknown	unknown	gnl|CDD|235493
NZ_CP023688.1|WP_003982370.1|6845922_6846792_+|endo-alpha-1,4-polygalactosaminidase	unknown	unknown	gnl|CDD|377061
NZ_CP023688.1|WP_003983447.1|6829643_6832304_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	unknown	unknown	gnl|CDD|236500
NZ_CP023688.1|WP_003983445.1|6827400_6828348_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236229
NZ_CP023688.1|WP_032922607.1|6841758_6843261_+|DUF3492-domain-containing-protein	unknown	unknown	gnl|CDD|340841
NZ_CP023688.1|WP_086026256.1|6826638_6827211_-|DUF4240-domain-containing-protein	unknown	unknown	gnl|CDD|379426
NZ_CP023688.1|WP_003982369.1|6845230_6845926_+|hypothetical-protein	unknown	unknown	gnl|CDD|371915
NZ_CP023688.1|WP_003983448.1|6832730_6833354_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP023688.1|WP_003983446.1|6828450_6829422_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	8.7e-54	177.8	3.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_003983443.1|6826088_6826580_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.16791e-19
NZ_CP023688.1|WP_003983439.1|6820239_6821055_-|lipoyl(octanoyl)-transferase-LipB	gnl|CDD|184638	PRK14345, PRK14345, lipoyl(octanoyl) transferase LipB.	1.74982e-113
NZ_CP023688.1|WP_030190118.1|6825099_6826050_-|TIGR01777-family-protein	gnl|CDD|273800	TIGR01777, Hypothetical_UPF0105_protein_Rv2216/MT2273/Mb2239., TIGR01777 family protein. This model represents a clade of proteins of unknown function including the E. coli yfcH protein. [Hypothetical proteins, Conserved].	2.20369e-130
NZ_CP023688.1|WP_003987033.1|6837146_6838691_-|leucyl-aminopeptidase	gnl|CDD|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP023688.1|WP_086026302.1|6835411_6836818_-|dihydrolipoyl-dehydrogenase	gnl|CDD|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NZ_CP023688.1|WP_030180224.1|6833528_6835358_-|2-oxoglutarate-dehydrogenase,-E2-component,-dihydrolipoamide-succinyltransferase	gnl|CDD|200219	TIGR02927, putative_dihydrolipoamide_acyltransferase, 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase. This model represents an Actinobacterial clade of E2 enzyme, a component of the 2-oxoglutarate dehydrogenase complex involved in the TCA cycle. These proteins have multiple domains including the catalytic domain (pfam00198), one or two biotin domains (pfam00364) and an E3-component binding domain (pfam02817).	0
NZ_CP023688.1|WP_003983446.1|6828450_6829422_-|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.33997e-43
NZ_CP023688.1|WP_003983441.1|6823063_6824290_-|FAD-dependent-oxidoreductase	gnl|CDD|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	4.9538e-34
NZ_CP023688.1|WP_003983438.1|6819132_6820083_-|lipoyl-synthase	gnl|CDD|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0
NZ_CP023688.1|WP_003982370.1|6845922_6846792_+|endo-alpha-1,4-polygalactosaminidase	gnl|CDD|377061	pfam03537, Glyco_hydro_114, Glycoside-hydrolase family GH114. This family is recognized as a glycosyl-hydrolase family, number 114. It is endo-alpha-1,4-polygalactosaminidase, a rare enzyme. It is proposed to be TIM-barrel, the most common structure amongst the catalytic domains of glycosyl-hydrolases.	4.72105e-103
NZ_CP023688.1|WP_003983447.1|6829643_6832304_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type	gnl|CDD|236500	PRK09405, aceE, pyruvate dehydrogenase subunit E1; Reviewed.	0
NZ_CP023688.1|WP_003983445.1|6827400_6828348_+|SDR-family-oxidoreductase	gnl|CDD|236229	PRK08303, PRK08303, short chain dehydrogenase; Provisional.	0
NZ_CP023688.1|WP_032922607.1|6841758_6843261_+|DUF3492-domain-containing-protein	gnl|CDD|340841	cd03813, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.	2.96905e-124
NZ_CP023688.1|WP_086026256.1|6826638_6827211_-|DUF4240-domain-containing-protein	gnl|CDD|379426	pfam14024, DUF4240, Protein of unknown function (DUF4240). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 169 and 263 amino acids in length. This domain is often associated with the WGR domain pfam05406.	1.39301e-53
NZ_CP023688.1|WP_003982369.1|6845230_6845926_+|hypothetical-protein	gnl|CDD|371915	pfam12138, Spherulin4, Spherulation-specific family 4. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.	4.58214e-41
NZ_CP023688.1|WP_003983448.1|6832730_6833354_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.25667e-35

Protein sequences

>NZ_CP023688.1|WP_003983447.1|6829643_6832304_-|pyruvate-dehydrogenase-(acetyl-transferring),-homodimeric-type
MPDPVRMPYSQLDQVPDRDPEETAEWRESLDAVTKAAGEHRAAYLMRRAVEHTGAPGLAPLETDYVNTIPTAAEPEFPGDEAMEARITAWNRWNAAAMVTRGSRLGLGGHIATFASAAWLYETGFQHFFRGKEADGSGDQLYIQGHASPGIYARAFLEGRLTEDQLDRFRQEAAGDGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLEHRGIKDTSNSHVWAFLGDGEMDEPESTAALALAGREGLDNLTFVINCNLQRLDGPVRPNYKIVQELEAQFRAAGWNVIKSLWGRAWDEVFAQDTDGALLRRLRETPDAQFQTYATRDAAYLREHFFGADPSLGRIAQGLSDAKLLELFQTSRAGHEPRKVYAAYKAAVEHKGAPTVILAQTVKGYTLGEGFESRNANHQMKKLTGEQFRTMRDLLELPIPDSALDADVVPYAHPGANSPEMEYLRERRAALGGPAPARKVVAKPLPMPADKAFDALKKGSGSQEIATTMAFVRLVKDLMRDKETGKRWVPVVPDEARTFGMESLFPSAGLYSPVGQTYDPVDRDQLLYYKEAKDGQILNEGITEAGSLADFTAAATSYATHGEPMIPFYIFYSMFGWQRTADQFWALADQLGRGFVIGATAGRTTMTGEGLQHADGHSHLIASTNPAALSYDPAFAYEVAVIVKEGLRRMYGPDAEDIFYYLTVYNETKVQPAMPEGVEEGILKGLYRFKEAGPAAADAPRLQLLASGTAIHWILEAQEILARDWGVAADVWSAPSWTELRRDALECDAARLEGEDRIPYVTRALAGVPGPVVAVSDWMRAVPDQIAPWVEQDWTSIGTDGFGLSDTREAARRHFGVDAQSVVVQALAALSRRGDVKAETVKEAKERYGL
>NZ_CP023688.1|WP_003983446.1|6828450_6829422_-|YafY-family-transcriptional-regulator
MRAARLIRMVLLLQSRPSMTAAELARELEVSERTVARDVLSLSEAGVPVYADRGRAGGYRLIGGYRTRLTGLGRSEVEALFLSGVPAALRDMGLADAASAARLKVSAALLPELRDAADGAAQRFHLDAPAWYREPATPELLPAVADAVWDDRRVAARYRRKDTEVERELEPYGLVLKAGVWYLAARAGEDVRVYRIDRFTSVTLLDDRFTRDPDFDLPAFWAERAAQFARSILRDEVTVRLTPAGARQLRHVTDRAGADEALAAAGEPDEQGRITVTLPVESLDVAFSQLLGLGPEGEVLAPAALRERFAEAAARTYGLYRES
>NZ_CP023688.1|WP_003983445.1|6827400_6828348_+|SDR-family-oxidoreductase
MAATTTTPGPLTGKVALVAGATRGAGRAMAVELGRGGATVYVTGRTTRGHISEVGRSSETIEETAELVTAAGAPAGGTGVAVPTDHLDPAAVRALTGRIDREQGRLDLLVNDLWGGDVHVEWGKKMWEHDLEKGLRVLRLGVESHIITSSCALPLLIRRPGGLVVEVTDGTEEFNRRYREPFYYDLAKSAPIRMAKGLAEELPEYGCTAVCVTPGWLRSEAMLDTHFKVTEENWRAGCAQNPHFAISETPVFVGRAVAALAADPEVARFNGQALSSGGLAKEYGFTDVDGSAPDAWRYITEVEQAGKPADTTGYR
>NZ_CP023688.1|WP_086026256.1|6826638_6827211_-|DUF4240-domain-containing-protein
MWGSPRAAPRGSNDAGPVMDETEFWQLIDSSREAAEGDPEEQADALVERLVALDPDSVVDFARHFESRYNRAYTWDLWAAAALLLGGAGDDAFDYFRCWLIGQGREIFEGALHDPDNLADLLDMFDEEVDGDAEELGYAADEAYEQLTGAEMPDLGLPAQPPEPLGTYIDNDDDRALAERLPRLWDRFGT
>NZ_CP023688.1|WP_003983443.1|6826088_6826580_+|GNAT-family-N-acetyltransferase
MSESFVRTAVLADEEPLAVLDRRTWSTLHAVTPRPQPPYDRFFDDRHRPEDLLVAEIAGRLAGYIRLVPPTPLPCNAHVRQIQGLAVDTWARGRGVARTLLDAACARALDEGARRVTLRVLGHNAPARRLYEAAGFSVEGVLPEEFLLEGKYVDDVMMGKMLV
>NZ_CP023688.1|WP_030190118.1|6825099_6826050_-|TIGR01777-family-protein
MAAMRIAITGSAGLIGTALVGSLRAGRPDQPSDGAGTGTGTGGHEIVRLVRHAPRAADEVRWDPKRQTVDAAGLAGCDAVVHLAGAGVGDHRWTDAYKREIRDSRVLGTAALAEAIAALDTPPRVFVCGSAIGFYGDTGDRRTDESAPPGDDFLARVCVDWEEAAAPAVEAGIRTVFARTGLVVGRQGGAWGRLFPVFKLGLGGRLGSGDQYWSFISLHDHIAALRHLIDTDGLSGPVNLTAPEPVTNREVTAAMGRVLHRPTPFPVPAPALRLALGEFADNVLASQRIIPQRLLDSGYTFTHPTADEAIRAAVGG
>NZ_CP023688.1|WP_003983441.1|6823063_6824290_-|FAD-dependent-oxidoreductase
MLRTASTVDVVIVGAGLAGLAAAHHLTSAGATVTVLEAAPYVGGRTSTDHLDGFRLDRTGQLLVTSYPELRTTPGLSGLVLRHFAPGLCLHNGRRNQRVGAPRSTRGALSAARALSRAERRADRSAAQVLAARPVFPPYIPDGFLRPLLSALLCDPGLTGSSRNAALALRSFARGRLCLPAGGASTLPELLAASLPPGTVRTSVRAVSVSTTGVGTAAHGQFPCRAALVATGARDAAGLLPGLRVPDFHPVTIVHHTTDSPPAPEPVVFLPSEGPVAHTFVASEADPSRAPAGRALVTTTVLGAPATLPARALDKTVRPQLDRIYGTSTDTWDLLAVHHDPEAVPAMPVPDDPHRSVRLLAGLYVCGDHRDTGTVQGALRSGRRAARAALDDLRLPPFREPCELSAAA
>NZ_CP023688.1|WP_003983440.1|6821416_6822979_+|hypothetical-protein
MTDRPPQRTPNRQLAALIAEAGFSNAGLARRVDQLGLEHGLDLRYDKTSVTRWLRGQQPRGTTPALIAEVFTRRLGRRLSAQDLGLDACAPVYAGLEFAATPSEAVDIVSGLWRKDSGSHAELRKIAFTPAGLVVPSRDWLIGRADERVAHGEAAEPAGRLPAPGRMQVAVPRQRQMERPGHERPTHERPGHERPPGHTERPGRTERPERAERSDRAHTYRVSAGDIKALRSVGELFRALDHAYGGGHARQALVRYLEHEVEPMLRGTYGEAAGRRLFAAAADLTRLAGWTSYDIAAHGLAQRYFVQALRLAQAAGDRAYGAYVLVTMSRQAVYLGHGREAVQLARVAQQGVGSNAPPGVQALLHAAEARGHGVLTEVRACTASLARAERALETARPGDDTPYWARFFDEAQLADELAHCHRDLQQFRAAAQHAERSLQLRGAGFARSRLFCRVVLATARLGLGELEQACALGAEAALQASEMRSVRAHEYVREFERRLEPYRDAAAVRGYRDRVAAIKA
>NZ_CP023688.1|WP_003983439.1|6820239_6821055_-|lipoyl(octanoyl)-transferase-LipB
MTAISRGDTPAPEGLRFVHLGFGAHAVDYEEAWQEQRRVHAARFADEIPDTCLLLEHPPVYTAGRRTEASERPLDGTPVIDVDRGGKITWHGPGQLVGYPIQKLPRPVDVVAHVRRLEEALIRACAEFGLETTRVEGRSGVWVLGDPVADRPSLGGLSLDFDPRTADEEFDPRLNGPEYAPSNAGQRREDRKLAAIGIRVAKGVTMHGFSLNVNPDNTSFDKIVPCGIRDAGVTSLANELGREITIADVLPVVEKHLRAVLENAVLLPRAV
>NZ_CP023688.1|WP_003983438.1|6819132_6820083_-|lipoyl-synthase
MSAVAPDGRKMLRLEVRNSQTPIERKPEWIKTRAKMGPEYNHLQGLVKKEGLHTVCQEAGCPNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPQELDRDEPRRVAESVQTMGLKYATITGVARDDLEDGGAWLYAETVRQIHAAMPGTGVELLIPDFNAVPEQLAEVFSSRPEVLAHNVETVPRIFKRIRPGFRYERSLEVITKAREAGLVTKSNLILGMGEERAEISQALQDLHDAGCELITITQYLRPSVRHHPIERWVKPAEFVELKEEAEEIGYAGVMSGPLVRSSYRAGRLYQQAIERRQVEESAQAV
>NZ_CP023688.1|WP_003983448.1|6832730_6833354_-|GntR-family-transcriptional-regulator
MTPPVVHSLREQIREHILEGIVSGRWQPGERIVERRIAVELAVSQTPVREALRELESLQLIESAPNKGVRVRNLTADDLKESYPVRAGLEQVAAELAAGRLAEDTAALDREVAALCEADRHGDGEAQVRHTVAFHREIVRAARNAVLLHTWESLGVEVWTTLSIRWFSPEPRSHARDHQEIVDAFRRRDPRIGELLKTHVLSCAPRV
>NZ_CP023688.1|WP_030180224.1|6833528_6835358_-|2-oxoglutarate-dehydrogenase,-E2-component,-dihydrolipoamide-succinyltransferase
MAVSVTLPALGESVTEGTVTRWLKAEGERVEADEPLLEVSTDKVDTEIPAPAAGVLASIKVAEDETVEVGAELAIIDDGSGAPAAESAPAQAEAPAAQPEPAAAPAQEAPAQEAPKQEAPAAPAGGAQGSGASTGSTGASGTDVLLPALGESVTEGTVTRWLKEVGEEVAEDEPLLEVSTDKVDTEIPAPTAGTLLEILVGEDETAEVGAKLAVIGQKGAAPAQAEAPAAPAPAQEAPKQEAPKQEAPKQEAPAPAPAPQAPTTPAPQAVTTPAPDPVPAAPAPAPAAAPVTPAPAAGEADAAYVTPLVRKLAQENGVNLATVKGTGVGGRIRKQDVIAAAEAAKQAAPAAAAAPAASGTKAPAIEASPLRGQTVKMPRMRKVIGDNMMKALHGQAQLTSVVEVDITKIMRMRNKAKDAFAQREGVKLSPMPFFVKAAVQALKAHPVVNARINEDEGTITYFDTENIGIAVDAEKGLMTPVIKGAGDLNIAGIARKTAELAGKVRTNKISPDDMSGATFTISNTGSRGALFDTVIVPPNQVGILGIGATVKRPVVVDHPELGETIAVRHMTYLALSYDHRLVDGADAARYLTTVKQILEAGEFETEIGL
>NZ_CP023688.1|WP_086026302.1|6835411_6836818_-|dihydrolipoyl-dehydrogenase
MHGGRDVANDASTVFDLVILGGGSGGYAAALRGAQLGLDVALIEKNKLGGTCLHNGCIPTKALLHAGEIADQAREAAQFGVKASFEGIDIEGVHKYKDEVISGLYKGLQGLVASRKVTYIEGEGRLSSPTSVDVNGQRVQGRHILLATGSVPKSLPGLNIDGDRIISSDHALKLDRVPKSAIVLGGGVIGVEFASAWKSFGTDVTIVEGLKHLVPVEDENSSKLLERAFRKRGIKFNLGTFFDKAEYTQDGVKVTLADGKSFEAEVLLVAIGRGPVSQGLGYEEAGVAMDRGYVLVDEYMQTNVPTISAVGDLVPTLQLAHVGFAEGILVAERLAGLKTVPIDYDGVPRVTYCHPEVASVGITEAKAKELYGADKVVALKYNLAGNGKSKILKTAGEIKLVQVKDGAVVGVHMVGDRMGEQVGEAQLVYNWEALPAEVAQLIHAHPTQNEALGEAHLALAGKPLHSHD
>NZ_CP023688.1|WP_003987033.1|6837146_6838691_-|leucyl-aminopeptidase
MTALTLSTSSAATLRADAVVVGLAKGAKGAVLAPGAEAVDKAFDGKLAAVLETLGASGAEGEVTKLPAASGLKAAVVLAVGLGKAPAEDADYDAEALRRAAGSAARALAGSKKAAFALPAEDAEAVAAIGEGALLGAYAFSAYRSNGDAKAARGAKKADDKSAPLAEVAILGGKPRDKAHKAAVERAQTLAAEVNRARDLINTPSNDLTPKSFAAQAQAAAKEFGLKVEVLDERALKKGGYGGLMGVGQGSENPPRLVRIGYTHAKAEKTLALVGKGITYDSGGISLKPAGHNETMKCDMSGAAAVFAAVVAAARLGLRVNVTGWLALAENMPSGAALRPGDVLTMYSGKTVEVLNTDAEGRLVLADALTRASEEQPDAIVDVATLTGAMVLALGNRTFGIMANDDAFRASLHEIAEEAGEPSWPMPMPSELRKGLDSPIADLKNVGERAGGGLLAGVFLQEFVGEGIPWAHLDIAGPAFHESAPFGYTPKGGTGSAVRTLVGLAERTAEGDLG
>NZ_CP023688.1|WP_003987031.1|6839054_6841145_+|hypothetical-protein
MGSNSKSSIRPARILTALATAFVTALPLAVATTPAQAAPAAADVVPRIDLRVLVITDGGDTTDAIASELRSQGIPYTTVNLSASGRPVINEAFLSDTVDGRPRAKFQGVVMSNDNPFGSADSPELAALKTYETTYKIPQVDAYTYARPDVGLRTPDEGGYAGVLDGFATRTTDAGKTGPFGYLKGAVPFEDADPKVSESYGYIAQPVANPPAGATFTTYLDAAVPGGPARGSLIGEYAHDGRRELVVTFAQNRYQQQFRLLARGIVDWLTQGVHLGQSRNYFSVQVDDIFAPDSRWDTKNNCTPGDFDCPPGVPDTAQIRMTEADAAYAAQWQRDRGYQLDLVYNAGSGEEWKAEHGGVDALADRLLADKSAYRWVNHTYTHPFLGCVQDTSTVPWRCAKDWFGQTRWVSRSEITAEIEKNHAWGVAKGLDVDASELVTGEHSGLKSTPQQPQDNPNLAPALTATGVKWLASDNSRESAQRQAGPALTVPRYPMNVFYNAATAAEETDEYNWIYTSKADGGSGICETDPNSTCLPAPLPTSTGYTSYIVPLEARTALGHALANDPRPHYIHQSNLAEDRIAYPVLDKVLADYRGFFAADTPVVNQRHRDIGREMQQRAAWQKALDAGSVTAYRIGDTVTITSPAGVAAAATMPDGTRTQLPNGTVDFGTRYAGRVSEWATAQSPGAAITLKLPTTA
>NZ_CP023688.1|WP_032922607.1|6841758_6843261_+|DUF3492-domain-containing-protein
MLTEGTYPHVHGGVSTWCDQLVRGMPEVRFNVIALTGSGREPVTWDLPANVYAQSSVPMWGPQPGRRTAGLRGRERRRFVDTYERFLLSMLDPQSCTDFGTELYALAALAREGRLSAALRTETALRSLMWIWTLPHVATRAAEPTVHDALTATDLLEHALRPLAVRIPRDSVAHAVSNGLACLPALAAKEFDEVPFLLTEHGIYLRERYLGYRRDAQRWPVKALMLGFYRQLTIESYRAADLVTPCNKYNTRWEERGGTPPEKIRTVYNGVDVQLFPHAEQEPDDPTLSWAGRIDPIKDLETLIRAYALCRAEVPNLRLRLFGGVPAGGEAYKTRCEKLAASLGVTDGLSWEGRIDDVARAYAAGSIVMLSSISEGFPFSLIEAMSCGRSTVSTDVGGVREAVGDTGLVVPPREPEAMAKATLELLKGGWEKRAELGSRARQRVIDQFTLRRSVDGFRTIYRELDGADRQAQETQESREEWTLQLRGPWRAPLAADGGGW
>NZ_CP023688.1|WP_030180221.1|6843257_6844721_+|hypothetical-protein
MSGPLWLVPGEGKDRTDDLPDVPRPQRPQWAAPDPVDELAGRMGDLIAAAVHPDEIAAIIESDGMSDDQIKLTYGRENSFALAEELYERVPRRYPEPDRVLTDPWRVSLLGCLLRALVFALPGLAYVVGSHLLSGPPDSRGLPAGTLPLLAGALAGWVWNQALAHRAYSWLGLGERWPAARSLAVGAPLGALFGAGVAWAVGVADADAPGAVAFAAGQAVYLGAATALLVFGQERWLLCALAPVGLGAALMAVYVPPDPVREGLLVLSLGAALALAAVTVWRCRSEPRHDGPAPRAVASVPYGLFGLAIGVLVLHTALGDVLRYGAHAEVAAPAAVALTLSMGPAEWLLYRYRSRAVAGLRASTTFAAFWRATSGALARCLACYLAVLALLGGVGSAVWRQGPPMDWAHALGLLCLGTVLWTALLLQAFGAVPVAAAVCGLAAIAQTVLLVAGPLSPAVAQLIVCGVAALVLGGLVSVLLGRATAHR
>NZ_CP023688.1|WP_003982369.1|6845230_6845926_+|hypothetical-protein
MTRPSSRQPRPPSRQLLVPLYEHPAERPDAWRRLIEAAPDLYGVVLNPASGPGTAPDRDFAEVARRLREAGVRILGYTDTDYGRRPHAAVAQDLLRHRDWYGADGAFFDQAAADAGLLAHYSRLTVAARAAGAGTVVLNHGLHPHPRYLDFADLLVTFENSWAAYENAEIPEWTAHHPPERFCHLIHGLPETCAEAAAELARQRGAAVHCAVPGTAPHPWDALPPFLETPR
>NZ_CP023688.1|WP_003982370.1|6845922_6846792_+|endo-alpha-1,4-polygalactosaminidase
MTSPRFRKRLLLLLGSLLLVTTACSQIPDGPDGKPSHGASPGTASPSSPGGGTGTHKPIWRPEPGTDWQWQLTGKLDLSVDAPVYDIDGFNHKAATVADLHKRGRKAICYISVGAYEDFRPDARRFPKNVIGEENGWKGERWLDIRRLDVLRPLMAKRFDMCRDKGFDAVEPDNVDGYKNKTGFDLTADDQLAFNRMIAKLAHDRGMSVGLKNDLDQIPQLVGDFDFAVNEQCAEYDECAAMTPFIKADKAVFHVEYELPASRFCRTSKRLGLSSMQKRLHLDAWRESC
>NZ_CP023688.1|WP_003982371.1|6846812_6847010_-|hypothetical-protein
MAHDNQPQRMSDTELEQFRELLRRYCAQELDQWEAWRLETPYGPVYVTLSRALPEGTDGSAYRPL

Crispr_ID: NZ_CP023688_10

• CRISPR_ID: NZ_CP023688_10
• CRISPR_location: 7640789-7640864
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP023688_10

Consensus_repeat	Method
GCGGGGCAGCCGAAACCGAACCG	CRISPRCasFinder

spacers of NZ_CP023688_10

>10.1|7640812|30|NZ_CP023688|CRISPRCasFinder
CCACCGACAAGCCCGCCGCAGGCGCGTACA

CRISPR arrays and Neighbor proteins around NZ_CP023688_10

CRISPR arrays

The CRISPR arrays of NZ_CP023688_10

>merge|NZ_CP023688|10|7640789-7640864|CRISPRCasFinder
GCGGGGCAGCCGAAACCGAACCGCCACCGACAAGCCCGCCGCAGGCGCGTACAGCGGGGCGGCCGAAACCGAACCG

>NZ_CP023688|10|9|7640789-7640864|CRISPRCasFinder
GCGGGGCAGCCGAAACCGAACCG	CCACCGACAAGCCCGCCGCAGGCGCGTACA
GCGGGGCGGCCGAAACCGAACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023688.1|WP_003985529.1|7648402_7650931_+|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234804
NZ_CP023688.1|WP_003985326.1|7630736_7631483_-|FadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225097
NZ_CP023688.1|WP_078575433.1|7643476_7644172_+|translation-initiation-factor-IF-3	unknown	unknown	gnl|CDD|234582
NZ_CP023688.1|WP_003985533.1|7644592_7644976_+|50S-ribosomal-protein-L20	unknown	unknown	gnl|CDD|179959
NZ_CP023688.1|WP_030178156.1|7632958_7634326_+|aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|365919
NZ_CP023688.1|WP_003985534.1|7644293_7644488_+|50S-ribosomal-protein-L35	unknown	unknown	gnl|CDD|234676
NZ_CP023688.1|WP_003985323.1|7627445_7628393_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176112
NZ_CP023688.1|WP_003985532.1|7645089_7645944_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|223640
NZ_CP023688.1|WP_003985538.1|7640912_7641647_+|SseB-family-protein	unknown	unknown	gnl|CDD|377787
NZ_CP023688.1|WP_003985329.1|7634326_7635112_+|3-oxoacyl-ACP-reductase	unknown	unknown	gnl|CDD|180371
NZ_CP023688.1|WP_003985531.1|7645988_7647137_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP023688.1|WP_003985530.1|7647278_7648403_+|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|234780
NZ_CP023688.1|WP_003985536.1|7642773_7643172_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP023688.1|WP_003987438.1|7639342_7640503_+|type-VII-secretion-associated-serine-protease-mycosin	unknown	unknown	gnl|CDD|274856
NZ_CP023688.1|WP_003985325.1|7629144_7630617_-|ethanolamine-permease	unknown	unknown	gnl|CDD|129986
NZ_CP023688.1|WP_003985324.1|7628412_7629105_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl|CDD|336781
NZ_CP023688.1|WP_003985331.1|7636571_7637789_-|amino-acid-deaminase/aldolase	unknown	unknown	gnl|CDD|143488
NZ_CP023688.1|WP_003985537.1|7641779_7642508_+|MIP-family-channel-protein	unknown	unknown	gnl|CDD|235453
NZ_CP023688.1|WP_003985330.1|7635240_7636542_+|haloacid-dehalogenase-like-hydrolase	unknown	unknown	gnl|CDD|319796
NZ_CP023688.1|WP_003985327.1|7631577_7632945_+|glutamine-synthetase	unknown	unknown	gnl|CDD|223252

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP023688.1|WP_003985529.1|7648402_7650931_+|phenylalanine--tRNA-ligase-subunit-beta	gnl|CDD|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NZ_CP023688.1|WP_003985326.1|7630736_7631483_-|FadR-family-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	6.29547e-34
NZ_CP023688.1|WP_078575433.1|7643476_7644172_+|translation-initiation-factor-IF-3	gnl|CDD|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	5.69462e-97
NZ_CP023688.1|WP_003985533.1|7644592_7644976_+|50S-ribosomal-protein-L20	gnl|CDD|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	1.46825e-60
NZ_CP023688.1|WP_030178156.1|7632958_7634326_+|aldehyde-dehydrogenase	gnl|CDD|365919	pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28. Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity.	0
NZ_CP023688.1|WP_003985534.1|7644293_7644488_+|50S-ribosomal-protein-L35	gnl|CDD|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	2.07436e-21
NZ_CP023688.1|WP_003985323.1|7627445_7628393_+|LysR-family-transcriptional-regulator	gnl|CDD|176112	cd08420, PBP2_CysL_like, C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold. CysL, also known as YwfK, is a regular of sulfur metabolism in Bacillus subtilis. Sulfur is required for the synthesis of proteins and essential cofactors in all living organism. Sulfur can be assimilated either from inorganic sources (sulfate and thiosulfate), or from organic sources (sulfate esters, sulfamates, and sulfonates). CysL activates the transcription of the cysJI operon encoding sulfite reductase, which reduces sulfite to sulfide. Both cysL mutant and cysJI mutant are unable to grow using sulfate or sulfite as the sulfur source. Like other LysR-type regulators, CysL also negatively regulates its own transcription. In Escherichia coli, three LysR-type activators are involved in the regulation of sulfur metabolism: CysB, Cbl and MetR. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.31901e-67
NZ_CP023688.1|WP_003985532.1|7645089_7645944_+|RNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.5394e-67
NZ_CP023688.1|WP_003985538.1|7640912_7641647_+|SseB-family-protein	gnl|CDD|377787	pfam07179, SseB, SseB protein N-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This entry contains the presumed N-terminal domain of SseB.	2.82151e-26
NZ_CP023688.1|WP_003985329.1|7634326_7635112_+|3-oxoacyl-ACP-reductase	gnl|CDD|180371	PRK06057, PRK06057, short chain dehydrogenase; Provisional.	0
NZ_CP023688.1|WP_003985531.1|7645988_7647137_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.65865e-51
NZ_CP023688.1|WP_003985530.1|7647278_7648403_+|phenylalanine--tRNA-ligase-subunit-alpha	gnl|CDD|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP023688.1|WP_003987438.1|7639342_7640503_+|type-VII-secretion-associated-serine-protease-mycosin	gnl|CDD|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	4.22974e-93
NZ_CP023688.1|WP_003985325.1|7629144_7630617_-|ethanolamine-permease	gnl|CDD|129986	TIGR00908, putative_ethanolamine_permease, ethanolamine permease. The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines].	3.07756e-136
NZ_CP023688.1|WP_003985324.1|7628412_7629105_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl|CDD|336781	pfam07722, Peptidase_C26, Peptidase C26. These peptidases have gamma-glutamyl hydrolase activity; that is they catalyze the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates. They are structurally related to pfam00117, but contain extensions in four loops and at the C-terminus.	1.1473e-85
NZ_CP023688.1|WP_003985331.1|7636571_7637789_-|amino-acid-deaminase/aldolase	gnl|CDD|143488	cd06813, PLPDE_III_DSD_D-TA_like_2, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 2. This subfamily is composed of uncharacterized bacterial proteins with similarity to eukaryotic D-serine dehydratases (DSD) and D-threonine aldolases (D-TA). DSD catalyzes the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia. D-TA reversibly catalyzes the aldol cleavage of D-threonine into glycine and acetaldehyde, and the synthesis of D-threonine from glycine and acetaldehyde. DSD and D-TA are fold type III PLP-dependent enzymes, similar to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM barrel domain and a C-terminal beta-sandwich domain. AR exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on their similarity to AR, it is possible members of this family also form dimers in solution.	0
NZ_CP023688.1|WP_003985537.1|7641779_7642508_+|MIP-family-channel-protein	gnl|CDD|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	4.23393e-72
NZ_CP023688.1|WP_003985330.1|7635240_7636542_+|haloacid-dehalogenase-like-hydrolase	gnl|CDD|319796	cd02612, HAD_PGPPase, phosphatidylglycerol-phosphate phosphatase, similar to Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C. This family includes Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C, PgpC (previously named yfhB) which catalyzes the dephosphorylation of phosphatidylglycerol-phosphate (PGP) to phosphatidylglycerol (PG). This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.49114e-05
NZ_CP023688.1|WP_003985327.1|7631577_7632945_+|glutamine-synthetase	gnl|CDD|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	2.28124e-140

Protein sequences

>NZ_CP023688.1|WP_003987438.1|7639342_7640503_+|type-VII-secretion-associated-serine-protease-mycosin
MTRRPLLRAAGVALSAAALTVLPALPAHADGIRAQEWALKAMNTQDAWETTKGEGITVAVLDTGVDASHPDLQGQVLPDNDLVGFGASPGDKAWAEHGTAMSGIIAGHGHGADRADGVVGVAPEAKILPVRVILEDSDPERKRARAERAGALADGIRWAADHGADVINLSLGDDSSSAHPEPREDAAIQYALGKGVPVIASAGNGGKDGDHVSYPAAYPGVIAVTAVDQWGSRANFSTRRWYATVCAPGVGVVIANPDRKYYEGWGTSAASAFVSGAVALIRAAHPDLSPAQIKQLLTDTAQDAPEGGRNDELGAGMVDPAAAIKEGNALKPTPQKPAPAAHTSHYFGPGPAAEQPSADPTWLPWTATIAGMALITASAIFWRKRT
>NZ_CP023688.1|WP_003985331.1|7636571_7637789_-|amino-acid-deaminase/aldolase
MSPYPCDTAADRARYDRATAHLDAPLALVDLDAFDANAADLVRRAQGKPLRVASKSVRCRALLERALARDGFTGVMSYTLAESLWLARSGIEDVLLAYPSADREGFAELAADPKLAAAVTVMVDDVAQLDLVDAARPAGGGEEIRVCLEWDTAYRPLGGRVRIGARRSPMNRPDQVAALARAVTRRPGFRVAGLMAYEGHVAGVGDAVAGHPLRSRAVQAMQAAARRDLARRRWEVVRAVRAEAPDLEFVNGGGTGSVQHTAAEAAVTEIAAGSGLYVPRLFDNYRSFTGRPAALFAQPVVRRPGKGVVTVLGGGYPASGVAGRDRSPVPYLPEGLRYDPQEEAGEVQTPLLGPAADGLRLGDKVWFRHAKAGELCERFAALHLVEGDRVVATVPTYRGEGRTFL
>NZ_CP023688.1|WP_003985330.1|7635240_7636542_+|haloacid-dehalogenase-like-hydrolase
MRTRHALALGLATAATVSTLAATGPAAAASPAHPAKAPERTSCPQLSKSIKWYGDNRAKIQRMIDERGICSHPKPGPEGRPVAAFDWDNTVVKNDISDATLAWSLQHDKILRPKSWKFTSPWMTTAADRALTKACGTSVPVGRPLRTSKNAACADEIMEIRGKARTMDGKAAFAGEWNHRRTKPEYAWIPQLFAGLTPAQVTSYAKQARAENLAAPIGAKQTVGTHQLAGYIRYYDQQKDLIRTLKAAGFQVYIVSASSETIAEAWSGGVGVDRAHTIGVRSLMKYGRFTTGIRGCGDVKDGHGEVLPYMDGKRCLINQEIFKIKGAEAWRFQDPAHRIALGGGDANTDVTFVNDATGVHLAINRNQPELMCRGYDNADGRWVVNPMFIEPLPQKSGTYPCATTGYTNTDGGLGPVRRPDGTVVADQRDRIHA
>NZ_CP023688.1|WP_003985329.1|7634326_7635112_+|3-oxoacyl-ACP-reductase
MTDQTPVCRRLVGRTAVITGAGSGIGLATARRLASEGANVVCADIDEKAGKAAAEDVGGTFVQVDVTDSDQVEALFKAAYDTYGSVDVAFNNAGISPADDDSILTTGLDAWKRVQEVNLTSVYLCCKHALPYMQRQGKGSIINTASFVAVMGAATSQISYTASKGGVLSMSRELGVQFAREGIRVNALCPGPVNTPLLKELFAKDPERAARRLVHVPVGRFAEPEEIAAAVAFLASDDSSFVNAAEFLVDGGIAGAYVTPV
>NZ_CP023688.1|WP_030178156.1|7632958_7634326_+|aldehyde-dehydrogenase
MLQELRIINPATEEQVAVVPVTTPAEVDEAVRRAAAAQQKWAALPPGDRARLLRRFAEVVRDNVPALARLELTEAGHPLGNAEWEANNVVDLLHYAAGGVERLTGRQIPVAGGLDITVQEPLGVVAVIAPWNFPMPIAAWGTAPALAAGNAVLLKPAETTPLTALRLAEYALEAGLPENLFQVLPGEGAVTGNALVEHPGVAKVVFTGSTATGRHIAARCAAQTKRLTLELGGKSPNIVFADADIERAAAAAPGSFLDNTGQDCCARSRILVQRSVHDRFMELLEPAVRSFVAGDPADPATQMGPLISAAQRERVRSYVPEDAPAAIRGEAPKGKGFWYPATVLEGRPDDRTAVEEIFGPVAVVIPFDDEADAIRLANATDYGLSGSIWTRDVGRALRVSGAVAAGNLSVNSHSSVRYWTPFGGYKQSGLGRELGPDALAAFTETKNIFISTEES
>NZ_CP023688.1|WP_003985327.1|7631577_7632945_+|glutamine-synthetase
MADRTPPLSVEELRRLVDAGEIDTVVLAFTDMQGRLTGKRFAARHFLDEVLEHGTEGCNYLLAVDVDVNTVQGYAMSSWEHGYGDFAMHGDAATLRRTPWNPGTALLTADLAWHDGSPVAASPRQILRSQLDRLAERGWSAYAGTELEFIVFRDTYEDAWNRGYRDLTPANQYNTDYSVLGTGRVEPLLRRIRNEMGAAGMTVESAKGECNLGQHEIAFRYDEALTTCDQHSVYKTGAKEIAAQEGMALTFMAKYNEREGNSCHIHLSLRDEAGQPVLADGSGPYGMSRVMRHFLAGQLAALRDFTLFYAPNINSYKRFRPGSFAPTAVAWGPDNRTCALRVIGHGPGHRLENRLPGGDVNPYLAVAAMVAAGLYGIEHELELPEACTGNAYTGDAEHVPTTLREAAALWEASPIAREAFGDAVVEHYLHMARVEQDAYDAAVTDWERFRSFERM
>NZ_CP023688.1|WP_003985326.1|7630736_7631483_-|FadR-family-transcriptional-regulator
MADGRGERPADRLAPVLRPVRAGNGFEEALEQILQVVRLGLVAAGERLPAERELAERLHISRVTLREVLKVLQDEGLVESRRGRYGGTFVRPRRQSADEDELRRRIDKVDVEDTLRFREVLEVGAAGLCAAHGLDDAQARRLREALAATHDAPLADYRRRDTLLHLTLAELAGSPSLAAQYAAVRAGVNELLDCIPLLVRNLEHSQAQHTALVEAVLEGDADGAREVMREHCAGTAALLRGFLTAPPP
>NZ_CP023688.1|WP_003985325.1|7629144_7630617_-|ethanolamine-permease
MADSTESRTAPPFDTAAGDSPPQDAYLQKRTLRRGSAGPLLLTGLGVAYVVSGDFSGWNNGLAQGGFGGLAIAALLMGVMYTCLVFALAELASILPTAGGGYGFARRALGTWGGFLTGTAILIEYVLAPAAISIFIGDYVESLGLFGLTSSWPVYLACFVVFIGIHLWGVGEALRFSLAVTAVAVAAVVVFAFGALSDFHVSALNDIPADASAFGSSSWLPFGVLGIWAAFPFGMWFFLGVEGVPLAAEETRDPARTLPKAMAAAMGILLLLALVTFVAATGARGSAAIQSVGDPLVQALQPHGKPTTVSRIVNYAGLAGLVASFFSLIFAGSRQLFALSRAGYLPRFLSLTSRRKAPYLALLVPGALGFALAAATGDGARMLNIAVFGATISYALMSLSHIVLRRREPRLPRPYRTPGGVLTSSTAFVLACSALVATFLVDKQAAFIALVVYGVALAYFALYSRHRLVAAAPEEEFAALAEAEAELERD
>NZ_CP023688.1|WP_003985324.1|7628412_7629105_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MSAQPLIGITTYLADDARWGVWALPAALLPAGYHRLVQRSGGLAALLPPGDPGTAAEVVARLDGLVIAGGPDVEPVRYGADPDPRTGPPARDRDIWELALIDAALQARVPLLGICRGMQLLNVALGGTLVQHIDGHAGPAGLFARHEVKPEPGTLLGGILPEAVSVPTYHHQSVDRLGNGLLPSAHATDGTVEALELPDADHFVLSVQWHPEAGDDTRVMEALVSAAGRN
>NZ_CP023688.1|WP_003985323.1|7627445_7628393_+|LysR-family-transcriptional-regulator
MASVNEERPGTGPVTPLAHRVPDLGALELLLAVARLGSLGRAARERGISQPAASSRIRSMEQQLGVSLVERSPRGSRLTDAGALVTDWARRVVEAAEAFDAGAQALRGRRDSRLRVAASMTIAEYLLPGWLIALRAQRPDTAVSLLAGNSAAVAERLLAGEADLGFVEGLDVPAGLDGAVIGHDRLVVVAAPTHPWARRRTDLTAAELAATPLILREHGSGTRQVLDAALAGHGGLAAPLLELASTTAVKAAAVSGAGPSVLSELAVGEELAARRLVEIPVHGTRFGRDLRAVWPSGQRPAGPARQLLGLTRAVP
>NZ_CP023688.1|WP_003985538.1|7640912_7641647_+|SseB-family-protein
MLKNIPTSDFSEDDGSADPELAAALADHAAAPTEATETRLLPLLSRARLLVPVVAVLGEVETGPDGLKREKTSDMAVPTLQAPDGRRALPAFTSMETLHRWRPDARPVAVPMRQALLAAAHEKADTVVIDLAGPATYQLTGAALRALAEGRESTDPLADPAVTDALRALLDAEPDVLVARLDPSAEADGTLSLGLAPDATPATVAQRLAPALAADETLRSRLIRGLDLALLPPGTDTAGAFFTR
>NZ_CP023688.1|WP_003985537.1|7641779_7642508_+|MIP-family-channel-protein
METTTETRTVVSEFLGTLLLVFFAVGSAVLAGEYIGTFGIALAFGFTLLALAYAIGPISGSHVNPAVTLGMLLAHRITPRTAIEYWIAQLLGGIVGAALLFLVAKQVPGLKTDEAFGSNGWGDRSAVHINLGGAFVAEIVLTFLLVFVVLAVTHRVAVVGFDGLPIGLALATVHLIGIPLTGTSVNPARSIGPALFAGGGALSQLWLFIVAPLIGGALAAVVHQVTHPPNEPKLVADERSAT
>NZ_CP023688.1|WP_003985536.1|7642773_7643172_-|hypothetical-protein
MSDQTPQQPGPAEPAGPAAPANPDFDAMTRDIADVPAVEVITTVAVHLMSSAAVNLGLAEDGAEHKDLDEARKLIQALAGLVTASATEIGSYHAAPLRDGLKSLQLAFREASVVPDEPGQGPGEKFTGPVYG
>NZ_CP023688.1|WP_078575433.1|7643476_7644172_+|translation-initiation-factor-IF-3
MRRGWSYRNRRYAAVRQAVAWCYRGGSISAEPRINDRIRVPEVRLVGPSGEQVGIVPLAKALELAQEYDLDLVEVAANARPPVCKLMDYGKFKYESAMKAREARKNQAHTVIKEMKLRPKIDPHDYDTKKGHVVRFLKQGDKVKITIMFRGREQSRPELGFRLLQRLAEDVQDLGFIESNPKQDGRNMIMVLGPHKKKTEAMAEAREAQAARKAERQGSAAEQGAEEPAEA
>NZ_CP023688.1|WP_003985534.1|7644293_7644488_+|50S-ribosomal-protein-L35
MPKNKTHSGASKRFKITGSGKVMRERAGKRHLLEHKSSRVTRRLTGNAVMAPGDAAKVKKLLGK
>NZ_CP023688.1|WP_003985533.1|7644592_7644976_+|50S-ribosomal-protein-L20
MARVKRAVNAHKKRRAILEQASGYRGQRSRLYRKAKEQVTHSLVYNYNDRKKRKGDFRQLWIQRINAAARANGMTYNRFVQGLKAANIEVDRKMLAELAVNDTNAFAALVEVAQKALPSDVNAPKAA
>NZ_CP023688.1|WP_003985532.1|7645089_7645944_+|RNA-methyltransferase
MGTPELISPRSARVAAARRLARRNFRGKERRFIAEGPQAVREAVAHRFAGERTLVELFATPEAAERHADIVGAVRAAGVPVHYAADATIAELSQTVTPQGLVGVCRFLDSPFEEILAARPKLVAVLANVRDPGNAGTVLRCADAAGADAVVLTDASVDLYNPKSVRASVGSLFHLPVAVGVPVEQVVAGLRGAGVRIVAADGAGAADLDAELDAGTMSGPTAWVFGNEAWGLPEETRALADAVVRVPIHGKAESLNLATAAAVCLYASARAQRTAGGCRSGSRG
>NZ_CP023688.1|WP_003985531.1|7645988_7647137_+|HAMP-domain-containing-histidine-kinase
MQSRARSTTVAAGSRPEGGDAPGPVPAGAPDLTGAGLDPDDLPDGLVVADETGRVICFNAAAARITAIAPHEALGRPLEKALPLQDIEGRRWWQLTDPYGGLAIRNGQPERNLLLGGREVLVSARYVRSRPTGPVRRLVVALRGTEARRRTELSHAELIATVAHELRSPLTSVKGFTATLLQKWERFTDDQKRLMLETVDADANRVTRLIAELLDISRIDSGRLEVRRQRVDMVAAVRRHVQAQTTAGQLPDRFLIRMVEPLPDLWADPDKIDQVLGNLLENAVRHGEGTVTIEVAPASDVSGAEGTSVTVSDEGPGIPEESMSRVFTRFWRGSKRGGTGLGLYIVKGIVEAHGGTITVGRAPAGGARFRFSLPVGTPAFMA
>NZ_CP023688.1|WP_003985530.1|7647278_7648403_+|phenylalanine--tRNA-ligase-subunit-alpha
MSAPNKSYDPVEVEALKPEEIARMRDEALAAIAAAGDLQELHEVKVAQTGGTSPLALANREIGALPPQAKADAGKRVGQARGQVSQALKARQEELEAERDARVLVEEAVDVTLPHDRVRPGARHPLTTLSERIEDVFVAMGYEVAEGPEVESEWLNFDALNIAPDHPARTMQDTFFVENEAAGEDQSGVVLRTHTSPVQIRTMLDREPPLYVICPGRVYRTDELDATHTPVFNQVELLAIDEGLTMADLRGTLDHMVKALFGDDIKTRLRPNYFPFTEPSAELDMVCYVCRGASVGDPQRPCRTCSSEGWIELGGCGMVNPRVLTACGVDPEKYSGFAFGFGIERMLMFRHNVEDMRDMVEGDVRFTRPFGMEI
>NZ_CP023688.1|WP_003985529.1|7648402_7650931_+|phenylalanine--tRNA-ligase-subunit-beta
MRVPLSWLREYVDLPAGESGRDVQAKLVATGLEVETVEQLGAGLKGPLVVGQVLTIEELEGFKKPIRFCTVDVGRANGTGEPQEIVCGARNFAVGDKVVVVLPGAVLPGDFKIAARKTYGKVSHGMICSGDELGMGDDGSGGIIVLPPEYEPGTDAIELLQLVDEVLDIAVTANRGDCLSMRGIAREAAIAYGLPLRDPALLDVPPPNSFGYPVKVADPLGCDRFTARTVVGLNPEARSPIWLQRRLQKAGMRPVSLAVDVTNYVMLELGQPLHAYDRSRVEGTIGVRRAEAGEKLTTLDGAQRVLDAEDLVITDNRGVIGLAGVMGGANTEIADPQTDPETGEVRGTTEVVVEAAHFDAVSVARTARRHKLSSEASKRFERGVDPQAASAAAQRTVDLLVLLAGGTAEAGVTEVVSPSGPRTITMRADHPDRVAGVPYGRETVVRRLQQVGCDVYGQDELVVTVPSWRPDLTDPNDLAEEVIRLEGYENLPLTLPRPPAGRGLTERQRLHRRVGRALAGAGYVEAPTYPFLGEAVLDQLGLEEDDPRRRTVKLVNPLSDEEPALRTTLVPGLLGALRRNDGRGSHDLALFETGLVFRPTGDEKPSVRLPVDRRPTDEEIAALDAALPEQPRRAAVVLTGAREQAGWWGKGRPADWADAIEAGRIVAREAGVELIVRQDQHAPWHPGRCAALLAVIDGEEVLVGNAGELHPRVIKALGLPERTCAMEIDLDRLQRAGGGVVQAPRISTYPVATQDVALIVDASVPAAEVAGALRDGAGELLESLRLFDVFTGEQVGEGKKSLAYALRFRAPDRTLTADEASAARDAAVAVAVERTGAVLRGA

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP023688_3	3.1|2659567|37|NZ_CP023688|CRISPRCasFinder	2659567-2659603	37	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	334970-335006	6	0.838
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	253740-253787	6	0.875
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP010991	Pseudonocardia sp. EC080625-04 plasmid pFRP1-2, complete sequence	39311-39340	7	0.767
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	MG945689	UNVERIFIED: Microviridae sp. isolate 1391-18011, complete genome	1175-1204	7	0.767
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	167002-167031	7	0.767
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP012163	Enterobacter roggenkampii strain 35734 plasmid p35734-109.753kb, complete sequence	40899-40928	8	0.733
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP009851	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH4 plasmid pENT-c88, complete sequence	28228-28257	8	0.733
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP050081	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence	310516-310545	8	0.733
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP049731	Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence	308554-308583	8	0.733
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NZ_CP053206	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence	308886-308915	8	0.733
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NC_009339	Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence	10119-10148	8	0.733
NZ_CP023688_10	10.1|7640812|30|NZ_CP023688|CRISPRCasFinder	7640812-7640841	30	NC_012848	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence	1016-1045	8	0.733
NZ_CP023688_3	3.1|2659567|37|NZ_CP023688|CRISPRCasFinder	2659567-2659603	37	NZ_CP015091	Pelagibaca abyssi strain JLT2014 plasmid pPABY1, complete sequence	75411-75447	9	0.757
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	KY250482	Corynebacterium phage phi16, complete genome	56101-56148	9	0.812
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	KF017927	Mycobacterium phage Odin, complete genome	4126-4173	9	0.812
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	MN284903	Mycobacterium phage GaugeLDP, complete genome	5561-5608	9	0.812
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	MK359341	Mycobacterium phage GingkoMaracino, complete genome	3702-3749	10	0.792
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	MH536825	Mycobacterium phage Ollie, complete genome	3702-3749	10	0.792
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	MN284900	Mycobacterium phage JeppNRM, complete genome	3867-3914	10	0.792
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	MH450128	Mycobacterium phage Reba, complete genome	3540-3587	10	0.792
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	MH371121	Mycobacterium phage Phranny, complete genome	3867-3914	10	0.792
NZ_CP023688_8	8.1|6426790|48|NZ_CP023688|CRISPRCasFinder	6426790-6426837	48	KF279418	Mycobacterium phage Anubis, complete genome	3702-3749	10	0.792

1. spacer 3.1|2659567|37|NZ_CP023688|CRISPRCasFinder matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 6, identity: 0.838

acgcggtcggcgtgcgcgccgtcgcccaccgcgccga---	CRISPR spacer
acgccgtcggcctgcgcgccgtcgc---cctcgccgaatc	Protospacer
**** ****** *************   ** ******   

2. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 6, identity: 0.875

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ttgatcccctgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
*.*.**************************..**************. 

3. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP010991 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-2, complete sequence) position: , mismatch: 7, identity: 0.767

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
tccccgccaagcccgccgccggcgcgaccg	Protospacer
.* *** ************ ******  *.

4. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to MG945689 (UNVERIFIED: Microviridae sp. isolate 1391-18011, complete genome) position: , mismatch: 7, identity: 0.767

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
gcgctgtcaaggccgccgcaggcgcgtagc	Protospacer
 *.*.* **** ****************  

5. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 7, identity: 0.767

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
tccccgccaagcccgccgccggcgcgaccg	Protospacer
.* *** ************ ******  *.

6. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP012163 (Enterobacter roggenkampii strain 35734 plasmid p35734-109.753kb, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
acggcgacaaacccgccgcaggcgcggtgt	Protospacer
 *. ******.***************    

7. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP009851 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH4 plasmid pENT-c88, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
acggcgacaaacccgccgcaggcgcggtgt	Protospacer
 *. ******.***************    

8. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP050081 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
gcaccggcaagcccgccccaggcggtctcg	Protospacer
 *****.********** ******  . *.

9. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP049731 (Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
gcaccggcaagcccgccccaggcggtctcg	Protospacer
 *****.********** ******  . *.

10. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NZ_CP053206 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
gcaccggcaagcccgccccaggcggtctcg	Protospacer
 *****.********** ******  . *.

11. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NC_009339 (Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
ccaccgacaagaccgccgcagctaccccaa	Protospacer
*********** ********* ..* .  *

12. spacer 10.1|7640812|30|NZ_CP023688|CRISPRCasFinder matches to NC_012848 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence) position: , mismatch: 8, identity: 0.733

ccaccgacaagcccgccgcaggcgcgtaca	CRISPR spacer
gcaccggcaagcccgccccaggcggtctcg	Protospacer
 *****.********** ******  . *.

13. spacer 3.1|2659567|37|NZ_CP023688|CRISPRCasFinder matches to NZ_CP015091 (Pelagibaca abyssi strain JLT2014 plasmid pPABY1, complete sequence) position: , mismatch: 9, identity: 0.757

---acgcggtcggcgtgcgcgccgtcgcccaccgcgccga	CRISPR spacer
gaggcgagatcga---gcgcgccgtcgcccaccgcgtcgt	Protospacer
   .** *.***.   ********************.** 

14. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to KY250482 (Corynebacterium phage phi16, complete genome) position: , mismatch: 9, identity: 0.812

---tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
caattgatcat---tagctcaattggcagagcatccggctgttaaccggac	Protospacer
   *.*.** .   ********************.*************** 

15. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to KF017927 (Mycobacterium phage Odin, complete genome) position: , mismatch: 9, identity: 0.812

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccaatgacgtgtagctcaattggcagagcacccggctgttaaccggac	Protospacer
.*..*  * *********************..*************** 

16. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to MN284903 (Mycobacterium phage GaugeLDP, complete genome) position: , mismatch: 9, identity: 0.812

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccactgacgtgtagctcaatcggcagagcatccggctgttaaccggac	Protospacer
.*. *  * ***********.**********.*************** 

17. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to MK359341 (Mycobacterium phage GingkoMaracino, complete genome) position: , mismatch: 10, identity: 0.792

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccactgacgtgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
.*. *  * *********************..**************. 

18. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to MH536825 (Mycobacterium phage Ollie, complete genome) position: , mismatch: 10, identity: 0.792

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccactgacgtgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
.*. *  * *********************..**************. 

19. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to MN284900 (Mycobacterium phage JeppNRM, complete genome) position: , mismatch: 10, identity: 0.792

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccattgacgtgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
.*. *  * *********************..**************. 

20. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to MH450128 (Mycobacterium phage Reba, complete genome) position: , mismatch: 10, identity: 0.792

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccattgacgtgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
.*. *  * *********************..**************. 

21. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to MH371121 (Mycobacterium phage Phranny, complete genome) position: , mismatch: 10, identity: 0.792

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccattgacgtgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
.*. *  * *********************..**************. 

22. spacer 8.1|6426790|48|NZ_CP023688|CRISPRCasFinder matches to KF279418 (Mycobacterium phage Anubis, complete genome) position: , mismatch: 10, identity: 0.792

tcggtcccctgtagctcaattggcagagcattcggctgttaaccggag	CRISPR spacer
ccactgacgtgtagctcaattggcagagcacccggctgttaaccgggc	Protospacer
.*. *  * *********************..**************. 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	823841 : 892841	52	Salisaeta_icosahedral_phage(16.67%)	tail,transposase,protease	NA
DBSCAN-SWA_2	1784689 : 1790986	7	Caulobacter_phage(16.67%)	NA	NA
DBSCAN-SWA_3	5397718 : 5403196	6	Mycobacterium_phage(33.33%)	NA	NA
DBSCAN-SWA_4	5420283 : 5446024	31	Streptomyces_phage(41.18%)	terminase,capsid,head,portal,protease	NA
DBSCAN-SWA_5	6658177 : 6665278	9	Streptomyces_phage(83.33%)	portal,capsid	NA
DBSCAN-SWA_6	6682143 : 6689851	15	Gordonia_phage(42.86%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP023688|823841:892841|DBSCAN-SWA
ATTATCCGGTGAGGGCTGTGTTGTGGAGGCGGGCGATGCCCAGGATGGCCTGGTGAACGCCGCTGCCCTTGAGGCGGCAGTCCCGCAGGATCTTCCAGTTCTTCAGGCGGGACAGGGCGTGCTCGACGCGTGCGCGGGCCTTGCGGTGGACCTTGTTCTCGGCTTCCTGCTGCGGGCTCAGGGTTTCCTGCCCGCGTCGACGGCGGTGAGGAATGAGCAGGCCGGTGCCCTGATATCCGCCATCGGCGAGCACCGGAACGCCTCGACAGGCGATGTCGACACCCGACTCGGTGAAGGCCCGGCAGTCGTTACGGCTGCCGGGCAGGGGAGCGCCGACGGCCACGACCAGGCGGCTGTTGGCGTCGATGACGACCTGCAGGTTCGTCGAGTACCGGTAGTTCTTGCTGGAAGCGGCGACGCTGCGGTCCCGGGTGGGAATCAGGGTGCCGTCGACGATGTAGACGGTGTCCTCGCGCTTGCGGCGGGCCGGTGAGATCGCCAGCAGCGGCGCGAGGTGGTCCAGGATCCGGTCCGCGGCCGACTTGGAGATCCCGAACAGCGGCGCGACCTGCCGCAACGTGAGGTTCGTGCGCCAGTACGTGGCAACCAGTAACACCCGGTCCTCCAGCGGCAACCGCCACGGCCGGCCTCGCTGGACGTCACCGCCACGACGACGCACCAGCGCGACCAGGCGGTTGAACTGTGCCGGACTCAGCCCGGTGAACGGCTCGATCCACTTCGGATCGTCTGCTGACATCACCCCACCCATGCCCCGATCAACGTCCCAGCGGCCCCATCAGTTACGGGACAACTTTTAGGGTGACGTTGACCGGCCCCAGCGTGACGGCCCGAAATGGCCCCATTTTGCGAAGACCGGCAACAGTACGGAGCAGTCCACGGCGAGGGCATGCCCGAGTACAGTGAGCTTAGGAATTTGCGAGACTTTCCTCGGCGTACTGCCGAAGGAAGGCATGAGCGGCATTGTCGATCTCTGCGACGGGGTCTGGGCAGCTTTCGAAGTCGAACCACTCCCCGTGGGTGCGCCTGACGTTGAATTGCTCATGCAGGTAGCGTTCAAGAGGGTACCCACCGCGAGCGCTCCAGCGAAGTTCCAGTGTGGTCGCAGAGCCTGACTGCAACGACTTGATCCGCTGGGCTATGTCCTTCGCAACACCGATCTTGATCGAGTCAGGGGCGCCGTCGGGCGATACGGCGTACACCCAGCGGTCATCGAAGCAACTCTCTTCGCGCACTGCACGAGGCGTGGGCTGCTCCATCAGTTCGATCATCTCCTCATACTCACGATTCTTCCGCTCGTTGATTGCAACTGCCAGGCGGACCAGCTTGTCTCGGGCCTGCTCGGCAGTGACCGATCCAGCTGTAATCAGATCGAGGAGCTCAATCACAGCCGGGACTTCGATGTCAGTGCCCCAGCTGGGAGCGTCTCTGCGCGTATCACCGTCCATCCCAACCCCCCATTGCAAGGTGACGTTCTCGATGCGGTGACTACCGAAGGCCAGGTGCACGGTGAAGGATTGGGCCACGAGGCGTCCTCTCAGGGGTGGTGGGGTGGTGCAGGGCAGGGCCATGGTCGCCGATGCCACTGACATTGGTGGTCGTGACGCTTGAAGGAGCGACTTCGGCTGGCCCCACTGGACTCGGGCATGCCCTCGCGGTGAACTGCTCCGTACTGTTGGCGATCTTCACAAAATGGGCCACTTTGGGTCGTCCCGCTGGGGCCGGTTCACGACGTCACAACCACTGGATCCCATGGACAGGGCCGAATCCGCTCCCGTTATGGCCAACCGCCGCTGTCCCCGGCGAGCCACGCCCACGCCTGATGGGAAAGTTCTGCGGCAGCGGCTGCCGTGTCGCACAGCTTCTTCGGGGCGGTGCTGCGGTGGACCACGCTCTCAAAAGCCGCGTCTGCTTTCGCTATGGAACCGGCAAGCCAAGCAGCCATTTCGGTGATGTCCAGCTCGGTCGCTCGCCATTTCAAGGTGAGTATGCCGTCGCGTACCTCGGACAGGTCGCAGTCACGTGCGGCGCTGCCGTACTTCTCGACCAGATGCACCCCGAGGTTGTCGGCGAGCATGGTGCTCGCACCGCCGCAGCACCGCTCGGCGTTCAGGAAGTTGTCCGCTCCTGGCGCCGCAAACTCCGAGAGCTTGCCGCACATGGTGCCCACCACCGCCACCACGCGCTGGGCGCACGCCATGAGTACCGGTGCAGGCAGGTCGGCGGTGGCTACCTTGCGCAGCGAGGCTTCCGCCGCTTGGAGCTGGGCGCGGACCGGAGCGGGCACTACCTCGTCGAGTCGTCCGTGCATCGTGTAACTGCCCTCCCCTGGAAGCGCTGCACGCGGTCGAACAGTGATGGTTCAACGCAGGCCACGTCAAGCACTCTGTCCCGGTTCCGGGACCGGAGGGGCCGGAGCAGGACCTGCTCGGAGCTCTTCTGCAAGGCAGCCGCAAAACGATTTTGTTCCCTGGTTACGAAACGGTAGCTGTACCAAGGCCCGTTAAGGTCCCCAGCTTTACCGGAACCGTTGCCCGACACCTTCTCGAACCAACGACACAATCACACCGCGCCTCACCGGCGTGGTGCCAGACCCACGCGTCGCCCGCCCCTGTGCGGCACCCGCGCAGGTCACCTCCTCATGGCCTTGCTCCCGTCGCCATCGTCCCCCTTCCGCCAGCGACGCCACCCTCGCCTTCACCATCCCGCTTACCGGCCGCCCCACACCTCGAACTCTGAGGTCGGCATCACGGCGAGCACGCCTAATCAGGCACCCGAACTTCCCACTGACGAACGTCTTCAAGGAGATGCATCTATGGCTGTCCGCACCCAGTTCCCCGTCGAGCACCAGTGCGGCCACTCGGTCGTCCACGACCTGTCCGACCGCCCCGCCGACCGCCGAGCCGGCTTCGCCCGCTGGCTCACAGGAAAGGACTGCACCGACTGCTGGAAGGCGGCGCGCGACGCCGACACCGGCTCCAAGGAAGCGTGGCTCGCCGCCAAGCGTGCCGAGGAGCAGCAAGCCGCCGCCGAGTGGGCCGAGAAGTTCGACATGCCGCCGCTGGAGGGCCCCGAGCGGGTCCTGGACTGGGGCGAGCGGTCCCGCCACCAGCTGATGACGGCCGCGCACACCGCGCTGGTCGTCGAGGGCGCCTGGGACGAGCCGGACTGGGCGGAACTGGAGGAGAAAGCGCGCGTGGTCACCCGCGCCGGATGGTGGATCGACCAGAGGGACGCGGAGGGCTCTGACCTGCTCGAACTCCTCGACGCCGCCACCGAGCAGGACCGTGGGACGGAGAACCCGTTCCGCTGAGTGAGGCCGGAACATAGCCGGGAATCGCCGGTTAGCCAAACCGGCGATCGTCCGGACTATTGATCCTCCCGCCGCCCGCTTCGCGTGGAAGGATCTGCATGAACCCGCCGTCCCGGACGCCTCCGCCGACCCCGGCCTTCGCACCGACGCACGACCCGCTGACCCCCGCGCGGGACATCACCCATCAGCACTTCCAGGCCGGCGACCAGGTCGTCGTCCTCAAAGGGGTCGCCGGCGGGGAGCTGTGGGGGGATGCGATGCGCGTCGTCGCCCCGTCCTGGCACACCCCGACCGACGAGGACGGATGGCGGCTGCGCGACGCCACCGGGGGCGCCCAGACCTACGTCACCGCCCACCCCCGCTACCTCGTACATCTTTCGCGCCGCTGCCCCGACTGCCTGATCTACCTCCGCGCCGTGGAGGACCACCTCCTGGCGAAGTACCCCGAGTCCGACACCCTGGTCGACTGCGGCTGGTACACCACCACGGCGCTCGGCCAGCTCGTGCACATCGCCGACGCCCAGAGCGGCCGGTGACCCTCCCCGTCCGCCGCCCCGGCCGCGCCCTGGCCCTGCTCACGGCGAAAGCCCGGGCCACCGCTGATTTGGGCGCCGCCTCCTGGCCGGACCGCCTGGCCCAGGACCTGCACGACCTCGATGCCGACTGGCGAGAGTCGGCGGAGGTGTGCGCGGATGTCGCCTGGACGGCACGCGCCGCGGGGCACAGCGTCCTCGACCTGCTGCCCCCGGCCCAGGTCACCGCCGCCGGCCCCGATCCGGTCACCACCCGCACCTTCCGGCATCTGTACCTGAGCGCCCTGCGGTTCGATTTCCGCTGCCCCACCCTCCAGGCCCTGGTCGAACAGCTGCCGGACACCGCGCTGCGGTCGCTGGACTGCTACAGCCGCGCTCTGTACGCCTTCGCGCTGCTGGGCCAGTCCCGCCCCGCGGGCCTGACCGTCATGGACGAGGTCCTCGCGGAGGCCGGGGAGCACGACAAAACGCTGCACGTACTGCTGCACGGGCTGTGGCTCGGCCAGGACCTGGACCAGGGCACGCAGCGGCTCCTGGCCCTCAGCGCCCGGCCGGCCTTCGCCCCCGGCACCGATCCGATCGTGCTCTTCCGCAGGGCCGGCGCGCTGCGCCGGCTCGGCCGCTACGACGATGGGCTCGCCGCCCTCGACCGGGCCCTGGATCTTCTGCCGCCCGGTGACATTGCGGTGCACGCCGACCTGGTGCGTGAGCGCTCCTTGATCTGCGCCGCCCGTGACCTCCACCAGCGCCTGCCCGCCCGCGCTTTCGGAGGCACGCCGACGTGATTCCGCGCGTCAACGAACGCACCCACACTCCGCACGACCCGCTCAGCGAGGCGCTGGGGCGCGGGGCGCCCATCGAGGGTGGTCTGACCGAGCACGCCGTCGTTGCCTACTGGCCGGGGCTGGACTCCTACCTTCTGGACGACGAGCAGGCGACGTGGACCGCCACTCAGTGGGCCGAGCACCTGGAAGATCCGCTTCTGGAGCATCCGTTCGCTGCCAGTCCCCGGGGCGACCGGCGGGCCATCTTCCACCTTGATGTGCGGCTGCATGCCGACGACCGGGACCTGTCCGGTGCGGAGTGGGCTGAGGCTGCCCACCGCCTGGCCCGCGCTGCCGGCATCGAGACGCCGGGCGACCCCAACGGCTGCCACTGGATCGCCGTCCACGGCAAACCCGGGCGCCTCGATGTGATCGCCAACCTCATCCGCCTGGACGGCGCGTGGCAGCGCCAGCCCGCCGACCTGATGCGGCGGCTCTCGGACGAGGCCCGCCTCATCGAAGCGGCCATGCGCCTCACCCCCGTTCGGACCGCCTCCCCGCAGCGGGGCAGTACCCGGCCTGTGCCGAGCGTTTCGGCAAAGTTCGCCGCGGTTCTCGCCCAGTTGGCCGACGAACAGGGCGGGCCGCTGGCCGCGGTGCGCGGCCTGATCGAGCACACCGCCCACCGCCTCGCCGACCAGCCGGGTACCGCCAGTCCCGACACCGCACATCACCTGGAGCTGATCGCCCGCCGCCTCTACGGCATCCAGCACGACCTCCACACCACCGCCACCCGCTTGAACCCTCCACCCCGGCCACACCCCGTCCTCCCGACACCGCCCACCGCCACGGCGGCCACGCGCCACTCACCGTAGGAGAATCGCTTCTTTGCCCCATGCCGACCGCTTCCTGACCGTGCGCCGCGATCCGCACTCCGAGGAGGTCCTGGCCCGCGGCGGCGATCCGCAGGCGCACAGCGTCCTCCAGCGAGCCGGGCTCGTCCCCGTCGTCCGCGTCCACGAGACCTACCACCGCGCCCCGGCCGGCCTCGCCCCCGACGAGGAGACCCGCCTCGCCACCGCAGCCGTCGCCCGGCTGCGCACCGCCGGCTACCACGTCGACTGCGACGCGGGCTTCGAGACCGACGCCCGGCCGGTCAGCTACCTGCCGCTGGGCGCCTCCGTCGCCCACCTCGCCGAGCGCATCCGCACGGCCACCACCACGGAGGAGGCGGCCGACGCCCTCACCGAGCTGACCGCCGCCCACGACGGCGTCCTTGCCGCCCTCGGCGACATCCTGGCCGCCACCGCCGAGTTCCACGAGGGCCTCGGTGATGCGGCCGACCCCCACATCGCCCGACGGCTGCGCTACCTCGCCGACGAGCGCCTGCACACCCTCCGCACCGACCTGTGCCATACCCGCAACGCCCTCGCCGACCGGCACGCCCCGCACCCCGGCCGCAGCACCTGCACCGAACAGGTCCCCGCCACCGAACGCGAGCGCTCCGCCGTATGCGCCTGCCCGCCTCCACCGCGCACGGCCCTGGCCCCGCCGCCTGCCGTGGCCGCCGGGCCGCGCCGCTGACCCCCACCTCGCTCAAGGACACCATGCACGACCACGAAAACTCCGAGCGCCTGGCCTCCTACGCCGACGTCCTGGCCGGTGAACTGCCCGACGCCTGGACCAGCACCTACCACCCGCCCGGCGCCAAGCACGATCTCGCCGAACTGGGCGACCGGATCTGGGACCTGGACCTGATCGCCGAATCCCTCGCCGAGCATCCGCTGCAGCAGGCAGCCGTCCTGAGCCGCCCGGACGGCGCCCAGCTCGCCGTCCTTGAACGGCACGACGAACGCGACGGCTTCCTCATCGCCGCCGTCGCCCCCCGCGCCCTCCCCGACGAGGCATACCGCGCAGTACCCGAGCCGAACGGCATCGCGCTGACCGACGATCCTTTCCTGAGCGCCGAGCAGGTCGCCGGCGACCTACTCGCCCGCTACGACACCGCGCTCGCCCAGGTGCGCCACAACGCTGCCGCCGACGTCCAGCCGTCCCAGCCGGAGCGGGTCGTCCTGACATGGCAGCCGGACGGCAGCCTGGCTGCCGCACCCGTCGGCGAGACGGCCGCCGCCGTCCTGGCGGCCAACAGCTTCGTCCCCGACCAGCAGACCGGCATCTACCGCCTCAGCGGAGACGACACCACCGTGCAGGCCCGCGCCGTGCGCGAGACCGGCCGCCAACTCGGCGCGCACGGCATCACCACCGCACTCCAGCATCCCTCGGGCCGGATCGCGCCCACCGCCACACCGGCTGCCGTGCCGCCGGCCCCCGCTACGTCCCGCACCCCGGCCAACAGGGCTCGATAACCCAACGCGGGCCCGGCTCCCGGGCGCTGCCACCGTGCGACAGCCCTCCGCCCCCAGCACGCCGTCGCTTAACTGGAGAACCGTCCATGGCCAATCTGGCCGACGAGCACGGCACCGACGTCGAGATCTGCGTCAAGCCGCTGACCACCACCATCCACGCCGACACTCCCACCGGCGCCCCCGAAAGGCTCCACACCCTGCTCGACCAGCTCGGTCTGGAACGCCAGGAGGTCCGCACCGCCGACCCCGTCTACATCTGGCACGTGGTGCCCGAGCATCTCGCCGCCGACGAGCAAAAGCGCCTGGCGACCCGGGCCATCCCCGCACTCCTTCAGGCCGGGTACCAGGTCAACTGCACCTCCGCCGTCTTCGACGAAGCCGTCTACCAGCAGGCCCTACGCGACCTGCACGCCACCCAGTCCCACCCGGCGGTGCAGCGCCCGGCTCCGGCCGCCTCCCCCGCGCGCCCCGCGCCGCCCCGGCGCACCCCCTAAGGCCCGGCGGGCGGCCCGGACCCCGCCGGGCCGCCCGCCCGCATCGCCCGACCCTTCGGAGAAACCCGTAGCTCCCCGCACACCCCCACCCACCACGAACCGTCTCAAGCCCCGCCTGGCCACCGCTTTGTTCCGCCGCTATCTGCGCGCCTGCCTCCCCACCGGGCCGGACCGCCCCTCCCCGCTGGCCGGCGCCCGCCCGGAGGCCGTCCGCGCCGAGTCCCAGCGGACCGGATACCACCAGCACCACTGACCGTTCCCGACCCGGAGGAGCATGTCCCACCCCACCCCGTACACGGTGCGGCTGGCCGACGAGATCACCCGCCAGCTCGGCCAGCTCGCCGACCACCTCGCTCAACTGCCCCCGCAGGAAGCCCCGCAGGCCCTCGCCCGCATCCTTGATCCCGACAACGGCGTCTTCGGCGGCGTCACCCACCTCGTGATCACAGGCAGCGTGTTCGCCAAGGCCGAGGCCGAACGGGGAGCGCTGCCAGCGGAGGTGTGGCTCGCCCTCGGCCGGGCCTCGAACGAACTCAACGACATCGCGCTGGGCCTGGACGAGCACCGCGAGACCCTCCAGCACGCCAGCGCCCACCCCGCCACCAGGGCGGCGCCGCCGGTGCCCGCTCCGCTCGTCGTCCGGCGGCGCCGGTGAAAAAGAAGCAGTGGCACAACTGGGGTGCGGGCGAGCAGGCCCAGCAGCACTACCTCGTCCAGCCCCGCGCCCTGGCCGGCGGCGGCGATGTCCGGCACGTCTCCGAATTTCTGCGCGCCTGCGGCTGGCGGGACAAGTCCAAAACGGACGGCCCTCTGTTCATGCAGAGCCCGGACCGCGCGGTCCGCATCGCCTACGACCCCTATGTCCAGCCGGGCGGGTGGAGCATCCACGGCGCCGCGAGCCGGCACCAGCCCGAGTGGTGGGCACACCTCGGCCGGCAGACGCCGGTGGAGATCGTCGCGGGCCTGACCGACGCCCTCACCCAGCCCCGGTCCGCGCACGCCCCCAACGTGTGGGCGCCGCTTCACGGGCAGCGCTGGCGCACTGAACCCGACGCTGAGCAGGTCACCGCAACCAGCCCCGACGGCAGCGCCTGGATGCAATACCACCAGAGCCCCGACGGCGCGGCGATGTGGTGGTCCGGGGCGAAGGACGAGCAGGGCAACGGCTGGAACGCCCAGTTCGCCTCGAGCACCCCGATGCACCTGGTGCAAGCCTTCTCGGCCGCCCTGGCCAGCCCCGAGCCCGTGATGCGCCCGCTCGGCCGTGTCCCGCCCAGCACCCAGATCAAGACCACGTCGGTGTCCGTCCTGCCGTCCCAGCTCAGCGCCTGGCAGCAGGCGCGCATCACTGCCGCCCGCGCCGCCACCTGGGCCCGCAACACCGCCCGCAGCGCCCGGCCCCGCACCGCGGCCCGCCCCCACGCTCACGCGGGCGGCCCCCGAGCCCGCCGCTGACCCCGCCGCCGACCTCCCGAGGAGCCTTGTGCCCGCACTCACCCCGGATGCCATCCGCACCGCGACCGAGACCCTGTCCCGCCTGACCGACTACCTGCGTGACAGCCCCGATCCCCAGCAGGCGCTCGACCTGGTCGAGCCGCTGCTGGACGAATACACCGGTCTTCCCGTCCAGCTCGCCGACGCCCTGCGCGCCCTGGCCCGCGCCGTACAGGAACACCCGGACACCCCGCGCAGCCTCGAAGCCGACCTGCTGGTCATGGAGTTGCGCACCGCCGCATGGGAACAGGCCGACCAGCACACCCTCCACTACGTCCTCGACGACCTGCGCGCGCTGCACGCCAGCGCCTGCGGCACCGAAGCGGAGTGTGGCCCGTGCCGGTGAGCGAACGGCAGCTCGCCGCCTTCGCCGACCAGCTCCCCCGGCGCATCCCCCTCGACACCAGCCCCCGTCACCTCGCCGGCGCCGGCGATGCCCGGCACGTCACCCACGCACTCGCCGCGGCCGGATGGGCCCGCACCTCCGACCCGTTCAGCCCCGAGGTCATCCTGCGCAGCCCGCAGGGCCGGTGCACCCTGCACTTCGACCCGCAGTCCGTCACCTCCGCATGGTGGCGGCTGCGGGGGCCGAGCCCACCGACACCGAGCCGGGCTGGTACGCCGAGTTCGGTGACCTCGTGCCCGCCGAGATCCTCGGCCGCCTCACCGACGCTCTCACCGGCCCGCCGCCGCCCCGGCCGCCGGGCCCGTTCCAGGCCCTCAAGTCGGCGGGATGGCTGTTGAGCGACGCGGGCACGGCCCACTCCCCTGACCGCATGTGCCATGTAGAACGCTGTCCTGATCAGGAGAGCCTCCGGGGCTTCTGGCACGTCGAGACCTGCGAGCCAGGGCACGGCACGCTGCTGGGCCCTCGCATCTGGCACGCCCGGTTCGACGGCCAGGTCCCCGACCATCTCGTTGGGCGCCTTCATCACCGGGCTCGCCGATCCCGCCCCGCTCCAGCGCGGCATGTTCGACCGCACCGCCCACCACAGCGTCGTGCAGGAACCCAGCTCGCGCACTCCCGAACAGGTCGTCGCCGCGCATGCCAACCGGCTCGATGCCATCCGCGCACAGGTACGCGCCGCCCGTCGCCAGCAACCGCCCCGCCCCGCCGCAGCCCCGCCCAGGGCCGGCGTACCCCGCTCGTCCGGCCGCCCACCGCTGACCCGTTAGGACCCCCGCCGTCTCCCCCGACCACACCGCTCACCGCGAGTTCCTGCAGCACCTCGACGACTATGTCCACGACAGCAAGGCGATCCTCGATGCCTGGGACGCCTACTCCGACGAGCACACCGACCTCGACGGCTGGCCGCACGACGACCACGCCTACGGGCTGCGCCAGAGCCAGCGCGACGCCGACACCGCCGCAGCATTCGAGAACATCCGCGCAGGCGCCCGCCACCTGCTGGCCACCGCCGAGGCACAGCTGCGGAGCATGCCGACCGGTGCGGTGCAAAGCCACTGGGTGTACCGGCTCGGGGTGCTGCATACCGCGCTCGACCGCCTCGACGCCCTGCACGAACAATGGCTGCTCACGCGCGGCAGCTTCCCCGCCGACGTCCGGCCGGGCACCCCCGCCTTCGACGAAGCGCTCGCCGAGCACCACGCCGAATCCTGGAGCTACCTGGACGACTGGGCCACCCACGGCCACGTCCTTAAGGACATCAACTCCGCATCCCGGCATTCCTCCACACCCCTGGCCCCGCCGCCGACCGCGACCGCTGCCCCTGCCCCCGGCCGGTCACCCTCGGTACGGAGATGACCGGGCCCCGGCACCCACACCACCACTGTCACACTCACCGGCCCCCCGAACGCGTGGAAACCCCGGTTCGGTGAGCACACGCCACCGCACCTGATCGCCGTTCCCAGCCCCCTTACCGCGCGCCAGCAGCCGTTCAGCCTCCCGACCGCCAGCCCGGTCTTGTGACGCGACCGGGACGCGCCCACCGAGCAGGTCCTCTCCCGCCGGGAAGACCACGTCCCCACCGCCCGTCGCGAGCATTCTGCCGACGAGCGCGAGCGAGCGCCCTGCGACGGCCGCCGGCCTGAAACGGCCGCAGCCGCTGGCCTCTTTGTCCCCGCCCGGAGGCACGTAGCCCCCTTGCCCCCCTCGTCCAACAGCTCCGACGGGTACGACATCGCCTTCCGGCTCCTCCTCGGAGTCCTCGCCATCGTCGTCCCCTTCTCGAACCTCGCCTGGCTGTCCGGCAACATCACCGCCTGCCTCACCGGCCTTCCGTGGGCGCCGTACCAGCCGACCGCAGCCCTGCTCCATCCCGACCAGCTCTGGCCTCAGGCCACAGAAACGTCCCTGCTTGTCGGCGCCCGCATCGTTCCCGGCGCCGTCCTCCTCGCCCTCGGCGCCGCAGCCGGTGTCCTGTGGGCCCGCCACAAGAACCGCAGCGGCAGTCGGAAGAAAAAGATCACCGGCATGGCCAAGGCGCGGGACATCGAGCCGCTGATGGCCAAGGCGATCGAGGCCAAGGCCCGGTCCCTGCGCCCGAGCCTGAAGGACACCAAGCACATCGAGGCCAAGGACACCGGCATTCTCCTCGGTAACCTCCAAGGCACCCCGCACGAGGTGCGGATGGGCTACGAGGATGTCGCCGTCGCGATCATGGCTCCGCGATCGGGGAAGACCACCTCGCTGGCGATCCCCTCCATCCTGTCCGCCCCCGGCCCTGTCCTGCTGACCTCGAACAAGGCGGCGGGCGACGCCTACACCACGACGCTCGACGCCCGAGCGGAAGTGGGACGGGTGTGGTCAATGGACCCGCAGCAGATCGCCCACGCCACTCGCGAGATGTGGTGGAACCCCCTCGCCACCGCGAAGACCCTGGACGGCGCCAACCGGCTGGCCGGCCACTTCGTCTCCGCCTCCGTGGACGCCTCGCAGCAGGGGGACTTCTGGTCGAAGGCCGGTTCCAACATCCTGAGCCAGTTGCTGCTGGCCGCTGCCCTCGACGAGCGTCCGATCACCGACATCATGGCCTGGCTGGCCTTCCCCGCCGACCGCACCCCGCTCGATATCCTGCGCGACCACGGCTTCGCCGCCGTCGCCGCCCAGCTCAAGGGCACCGTCGAGGGCCCGCCCGAGACCCGTGACGGCATCTACGAGACGGCCCGCCAGTACGCCGCGGCCCTCCTCAACGCCGAGATCGCGGCGTGGGTGACACCGCAGAAGGACGTCGCAGAGTTCCGGCCGTCGCAGTTCGTCACCTCCACCGACACGCTCTACCTGCTCAGCAAGGACGGCGGAGGCGGCGCTTCGGCACTGATCGCGGCGTGCGCGGACGCGGTGATGCGGGCGGCAACCGCCGAAGCTGAACGCGCCGGCGGACGTCTTGACCCGCCGGCTCTGGCGATCCTCGACGAGGCGGCCAACGTGTGCAAGATCAGCGACTTGCCGGACCTGTACTCCCACCTCGGCAGCCGCGGAATCATCCCCATCACCATCCTCCAGTCCTACCGGCAGGGCCAGAAAGTCTGGGGGGACGCGGGCATGGACGCCATGTGGTCCGCCTCGACCGTGAAGGTCATCGGCAGCGGAATCGACGATCCGGATTTCGCGGACAAGCTGAGCCGCATGATCGGCGACCACGACGTGGAAACCACCTCCATCTCGCACTCCGAGTCCGGGAAGTCGACCTCCGTGTCGATGCGCCAGGAGCGGATCCTGCCCGCCGACGCGATCCGCGCCCTGGCCAAGGGCACCGCCCTGTGCTTCGCCACCGGCATGCGCGCCGCCATGCTCGACCTGCGCCCCTGGTACGCCGAGCCCGGCGCCAAGGAGTTGTCCGCCGCCTCCGCCCGCGCCTCGAAGGCCATCACTGAGCGCGCCGTCGCCAAGGCAGCCCCCGCGCAGACCGACTTCACCACCGCCACCTGACCCCCGGCGCCCATGCCCCGGCCCTGACGCCGCCACCGAGCGGCAACTCTCCCACCCGACCACTGCTTTGCCCCTTCGGAGACCATGGCCTTCCTCGACCACAACGACGTCGTCATCGGATCCACTGACGACGGCCACACCTTCGTCCTGCTCAACCGGGCCCTCCCCGCAGCCCAGCGCATCCTGACCGACCACGGCTTCACCGCCCACCAGCCCAGCGGCCCGGGCCGCCCGCTGTACCTGCTACCGCCCGCCTACGCCGGGGAGCAGGCCAACACCCGCACCGGCGAAGCCATGCATTTCCTCTTCCAGCACACCTGGGACGTGACCGACCTCAGCTGGACCACCCGCTGGAACCCGGACGAGCCGCTGCCCGAACCGGACGTCCACTTCCATGTCTCCGGCGAGCGCGTCACCGCCACCGCCCGCACCGACGCCGCCCGCCGCATCCTGGCCAACCACGGCTTCACCCCCACCCGGGAGGGCTACGCCCTGCCCGTCGGCACAGATGAAACGCGACAGCTCGGTGCGGTCGTCCAGGCGGAGACCGCCCTGTCCATGGAGAACCTGGGCACCCGTATCCGGCTCGGCTTCCGCACGCCCGAGGACATCCCCGCAGCTCCCGCCCGTACGAGCAGCCACACCGCCACACCGCCCGCAGCCCCGGTTCCTGACCGGCCGCGCCGTACCCGCTGACCGCCCAGGCGAAGTGCCGAACTGGCCTCCAGGCCCGTCCCGTCCCGTCGCGGCGGGAGGACCACGATGACTGAGTCTCACGTGCGCAGTTCCACGCCGCCTGCCGGTCACACGCACCGGCTGTACCTGGCCCAGCTCTCGACTACCTGCACAAGAGCGAGCCAGCCGCCGAGCCAGTCCCCGCCCCTGCCCAGGCGAAACCCGCAGCCACCGCGAAGCCGTCCGCCCCGCGCCGGCGACCTTCGTAAACGCCTCCGCCGCCACGCGAACGCGGCGGCCCGGTACACCGCCGCAGGCCCCTCACCGAACGGAACCGTCCCGCCGCCGATGACCGCACCCACCGCTCCGGCCGAAAAGCTCCTGCTCCTGGGGGGCGATTTCGCCCGCCAGCACGACTACCTGTCCTGCCTGCGGCTGGACGGCCTCAGTCCGGCGACCGCTCTGACGCAGCAGTCCATCCCCACCCAGGATCTGGCCCGCTTGGCGCTGGACATCGTCGAGGGCCTCGACGCCCAGCGGATGTACCACAGCCCGGAGATCCGCACCGTGTACGCGCGGGTCCGGCAGCTCGCCCACCTGGCCATCGACACAGCCGACCACCTTCTGGACGCCGAGGACATCCTCGACGACACCTATGCCGGAGTTCCCGCCAAGGGCGAAGGGCCCCTGCTGACCTACCGGCAGGCCCTTGAGACGGCCAACAGCCGTCTCATCCTCGTCCGAAAGCTGACCGCCCCGGCCCCCCAGGACACGCTGACAGCCGCCGAACTCTTCGTCACCGAACGGCGCCGCCGCGGCGAGATCCCGCCGCAGCAGCCGCCCGCCTTCTCCCCCGCCCAGTACACCGCGCTGCGCGCGGTGGCCCGCGGCGAAGTGACGATCGCCGACGACAAGCCGTACCTGCACCGCGATGACTGGCGCATCGCCCTCAGCACTCTGCGCTCGCTGGAGGACCGCGGCCTCGTCGCCCGCGAGAAGTGCCCGCTGTGGCTGCACGACGAGCGGGTGCACCTGAGCGCCGACGGCCGCCGCGACCTGATCGCCACCTTCGGCCGGCCTCCGGCCCCCGCGCGCACCGCCGCCCGCCCGGCCCCGGCGCCCAAAGCCACCCCCAGCCGCTCTCTCTAACTCGTCCCCGGGAGATCTCACGCCCACCGACGACGCCCCCACCCCGCACGTCATCGCCCTCGCCCTCGCCGCCCAGATCCACCCGGAGGCCGCGCCCCGCGACGTAGTCGCCAGCTTCAATGTGCGGCGCCAGGCCGACCCCCGTTTCCGCCACCGGGGCTCCGGCGGCCCGGTGACCGTCGTGGCCCGCTCCCTGCACGCCCGCCTGTACGGCCTGCCCACCGCCCCTTCACCGCTGCCCACGGCCCTCGACGAACTCCTGCAGGTCCTCGGAACGGCACGCGACGGCGACCAGAAGCAGGCAGTACTGGTCCAGCTCGCCGACCAGCTGCGCAACGCCGCCGAAATCCTCGAATGGGCCCGGGACAACGCCCGCCAACTGCCCGCCCCCATCTGGGAATGGCTGCGCGACGCCACCGACACCACCCGCCACCTGGCCGATGGCCTCGACAGCGTGCGCCCTTCGTTCGCCGCGCCGCAGGCCCCCGCCGCACCGCTTCCGCCGCCGGCGCCCGCCCCGCCCCACGCCGCCCCCGCCCGGCGCTGACCGCACGCCCGCGGGCGCCGCCCCCGTACACCGCAAGGACGCCCCATTCCCGCAACCCCCGCCTTCCGATCCCTCTCCCTCGGCGCCGGAGTCCAGTCCAGTGCCCTGCTCGCCCTGTCCGCCGAGGGAATCCTCCCGCGCGTCGACTGCGCGATCTTCGCCGACACCGGCTGGGAGCCGGCAGCCGTCTACGCCCATCTCGACCGCCTGGAGAAGGAGGTAGCCGAACCAGCCGGGATACCCGTGCTGCGCGTCTCGGCCGGGAACATCCGCGAGGACGCGCTCAACCCCGGCCACCGGTTCGCGTCCATGCCGCTGCACGTCCTCAACCAGGACGGCAAGGCCGGGATGACCCGTCGGCAGTGCACCGGCGAATACAAGATCAAACCGATAAAGAAGCAGGTACGCGCCCTCCTGGGCTACCCGTATCCCCGGCGCATCCCCAAGGGCGTGTTCGTCGAGCAGTGGGTCGGGATCTCCACCGATGAGTTCCACCGGGCCAAGGACGCCGACGTCGCCTACATGCGCAACCGGCACCCCCTGATCGAGCTGGACTGGTCGCGCGCCGACTGTCTGCGCTACCTGAAGCAGCGCGGTCTGGCCGACACCCCGAAGTCGAGCTGCCTGGGCTGCCCTTTCCACGGCAACGCCCAGTGGCGGCACATCCGGGACCACAGCCCGGCCGAGTGGGCCGACGTCGTCGCCTTCGACGCGGCTATCCGCAGCGGCAACGCCCGCGCCAATGCTTCCGGCAACCGGCTGCTCGGCCAGGCGTTCTTGCACCGCTCCCGCGTCCCGCTCGACCAGGCACCCATCGACCACGTCACCGCCGCCGAATGGGCCGCTCGCCAAGCTGAATTGGGCGACCAGGCCCCGGATGGTGACGCCCGCGTCGTGCTGGAGGAGGGCGTGGCCGACGGCTGCTCGCCCTGGGCCTGCCGCGGCGAGCAGCCGACACAGGACGACTTCGGGCTGGCCGCATGATCGTGGACCTGTTCGCCGGACCCGGCGGCTGGTCCTACGCCCTGTCGCTGCTCGGCGTCCGGGACATCGGGCTGGAGCGGGACGCGTGGGCCTGCCGCACCCGCGCCGCAGCCGGGCAGCTGACACTGCGCACCGACGTCGCCCGCTATCCGGTGGGGCCGTTCGTCGGCCGCACCACCGGTGTGATCGCCTCGCCGCCGTGTCAGGCGTGGTCGATGGCCGGCAAGCGGCTCGGCCTGCTCGACCAGCCGCTGGTCCACCAGGCCGTCGCCGACCTGGCCGCCGGTCGCGACACCCGCGACAAGCTGCTCGGTGCCTGCCGGGATGAGCGGTCGCTGCTGGCCGCCGAGCCCATGCGCTACCTCCATGCGCTGAACACGGTGGGCGAGCCGGAATGGGTGGCCATGGAGGAGGTCCCCGACGTCGCACCGCTGTGGAAGCAGTACGCGGCGATCTTGCGGTCGTGGGGTTTCTCCGTGTGGTGCGGGATTCTCAACGCGGCCGACTTCGGGGTGCCCCAGACGCGGCGGCGGGCGATCCTGCTCGCCTCCCGTTCCCGCCCCGCCGAGCCCCCGCCGCCGACCCACGCACAACACGGCGAGCCGGAGACCCTGTTCGGGCCCGGCCGTGCGCCGTGGGTGTCCATGGCCGCAGCCCTCGGCTGGGGTGCCACCGACCGCCCGGTACCGACCGTGTGCGCCGGGGGCGGACCCGGCGGGGGCCCTGAGCCGTTTCCCTCCGGCTCGCGCAAAGCCCTGGCCGACGCCCGGGACCGCGGCACCTGGCAGCACCCACCGCGCCCCGCAGGCACCGAACGGCGCCTGCGGCGCCGCAGCCAGCCCGCCGTCGCGGCCCACGAGAGCCCACCGCCGTCCGCGCGCCCGGCACCGGAGTGGGCGTGGTCGCTGCGCACCAACAGCCAGACGAACGCCACCGTGCGCCGCGCCGACGAGCCCGCCGGCACCCTGTTCTTCGGACACCGCGCCAACGAATGCCTCTGGATCGCCGAACCCGCCACCACCACAGCGGGCGAGGACGCCCCCGTGCCGGAGGCAATCCGCATCACCGCCGCCGAGGCGGGCGTGCTGCAGACCTTCCCCGCCGACTACCCGTGGGCCGGCAACAAGGGCCAGCAGTTCTCCCAGATCGGCAACGCCGTCCCGCCCAGGCTCGCCGCCCACCTGCTGGCCCCGCACCTCGGCCGCCCCCTCGGCCCCGACGACTTCACCCTCGCCGCCTGATGCACCCCCGTCCCTCTGCACCCCGCCCTGACGAAGACGCCGAGCTGGCGGACGCGCATCCTCCGGCCCCGGTGCACTACGCCGAGCAGGCCCTGCTCGGCGCCCTCCTCCTCGAACCCGCACGCCTAGACGGACTCGGCCCGCTGGCCCCCGAGCACTTCGACGCCCCTGCCCACAGCGCCCTGTATACGGCCATGCACACCGCCCCTGTTCCCGACGCCGAACAGCACCGCCGCGCCCCGGTCTGGCTGGACCGCGTCCTGCAAGCCGCCCGGCCCCAGGCCCCCGGCCTGACCGCCTCCTACCTGCACACCCTCGTCCACCGCTGCCCCTGGCCCGGGCACGCAGCGGCCTACGCCCACATGATCCAGGCCGACCACACTCGCCGTACCGTGCGGGAGCACGCCGACCGCCTCGCCCAGGCCGCCACCGAGGCGTCGCTGCCCGACCCCACCGCCACCGTCCTGGCCCAGTGCGACACCCTCTCCAGCTTCCTGAACACGCTGTCGAGCCGGTTCGCCCCGCACCCGGGCTCCCTGCCCCGCACTCCCCACCCGGCCCCCGCCCGACGCACCGCCGGCGAGGAGGCGCTGGAGGAAGAACGGGCGCTGCTCGCGTGTGCGACCGCCCAGCCCTCCAGGCTGCGGGAGATGCGCTGGCTGCAACCCGACGACTTCGTTCTGCCGCTGCACGGGCAGCTCTTCACATGCCTGACCGCGCTGGTACACCGCCGCGAGCCCATCGATCCGGTCACCGTGCTGTGGGAAGCCCAGCACCAGCATCTGCTGCACGCCAACTTCACCCCCGCCGACCTGATCGGCCTGCTTGCCACCCCGGTCGGCACGCCCGAGCACTGGGGGGAGAAGATCCTGCGGCGCGCCCTGCTCGCCCAGGCTCACACCACCGCCGTGCAGATCCGGGCGTTCACCGACGATGCGGCCAACACCCCGCACCAGCTCGCCACCGGCAGCCGCCGCGCCCTGGCCAACCTGACCGCCCTGGGCACCCGCTGGCAGCGCGCCAGCCACGCTCCCGCCACACCGCGCTCCCCGGCCGTACCCCGCGCCGGGCCCCGCCTGCGGGCCGCCCCTGCCCCACCGACCACCCGCGTCTCCCGATAGCCCACCTGCCCGGCCGGGGCCCGGAAGCGAGCGCCATGCCCCACCCCGACACCGCCGCCCACGTCCGCCTCGACCGCCACCCCCACCACACCTCCGCCGTCACCGCCACCCTCACCGACTCCTCCCCCACCACCGCCCGGGCCCTGCTGAGCGTCCACGGCTTCCGTCCCACCGGCGAACACGCCCTCGTTCTGGCCCGCATCGACCACGAAGAGCCCCACTATGCCGAGCACGCCGCCCAGGCCCTGCGCGCGGCGGGCCTTACCGTCGAGATCACCCCCGTGCTCCAAGAAGACATCGACACCGAGTGGGACTGGGCAGGCCACCCCCTGCACTAGCTGGACCGCGACGAGATCCGGGACGTCTCCCACCAGGCCCAGCAGATCCACGACGACATCGCCCAGGGATGACGAAAGAGACGATGCAGCAAGTGCACGAGCGGGCAGCCGCAACGCGTGAGAAGATCCTCCGGGCAGCCTCCGAAGTGTTCGACGCATACGGCTACAGTGGCGCCAGCATCAGCAAGACCCTCACCCGGACCGGAATTACACCTGGTGCGCTGTATTTCCACTTCTCCGGCAAACAATGCCTGGCCCATGCCGTCATGCTCGGGCAGGGCGACGGCCTGAAGCTCCCAGGCGGCGAGGACGGCCTGCAACGCCTGATCGACATCAACCTCTACCTCGCGGGCGAACTGCAGACCAACGCCCTGCTGCGCGCCGGAGTCCGGCTGGCTGTCGAGCAGGGAGAATTCGGCACTCCGGACGACGCCCCCTACCAGTACTGGGTCCGTCTCTTCGCCTCCCAACTGCTGGCCGCCAAGGAAAAGGACGAGCTGCTGCCGGACGTGGACGTACAGGAACTGGCCTGGACGCTGGTCAGCTCCTATTCCGGCACGCAGCTCCTGTCCCAGATCGCCACCGGCCGCACCGACCTGCACGCCCGCCTGGTCGCCTTGTGGCGCTACCTGCTGCCCGGAATCGCCACCCCGGCTGCCCGGTCACGCGTGACCTTCAGCTCCCAATGGGACTGCCCGGCAGCGTAAAACCACCGGCACCCGGCAGGCTGCTACTGCGCCGGCCCCTGCAGACCGCGGTCCGCCAACCTGCGGGAAAGCACGCATACGCCCGGCGGATGCATGCCGCGAATCCCGTCTCGTTGCCGTCACCGGCTCGCCGTCGCCGCACGCAGGCGTGGCCAGCACCGAAGACAACGGCAGGCGTTTCCCGGAGGCGCCGGCAGGTGCGACCAGAGCGCCTCCGGGTTTTTCCAACTGCCGCCAACCTGACTGGCCATGAGGGGCGAAACGGATAGCATCAGGCCGGGCTCATAGGGATACTGGGACGATGGCCGAACGACAAATGCTGATGACGACGCAGGAGATCCGCGCCCTCATCAACGCCGCGCTCGCCGCCCCCTCGATTGACCTCGCTGTCCCCCTCGGGATGTCGCTCATGCTCCGTGAGGGCCTGCGCACCACCGTCCTGACGGCACTGTCTCGCGCGGACTACCACCCGGCGGTGGACGACGTACCTGGAAGCCTCACCTACCGCGACGGTGACCATGTCCGCGTAGCCACACTGTCTCCGGAAACGGAGTTTCTCCTGGCCGCTCACCTGGAGCAATGAGCCCGGCCCGCCCTCATCTCACGACCAGGGGCGGCAGCGGGCCGATGAGCAGCTGATGCCGCACGGCAAGGTCCGTGGACGCCGTCGAACAGGCACCGCCCTCTGTTGCTGCGCTTCGGAGCATTGCGCCGTTTGGCCAGCGCCGCGAGCGGTAGTCGCTTGGGGTCATGGCCACCTTCGACCGGTCGTCATCGTGGCGATCACGACGTCGAACGCGTCCCGAGTGCCATAGCGATCGGAGCGGGCGGCTCCCGAATTTAACGACGTGCTCGATTTTTCCCGGCCTTTGAGGCCGGGGCTGCCCTAGGGGTGTACTAAACGTTCAGTCCGCCCTGTCCGTCATCGCAGGAGTGCCGGATGCACTTCGACACGGGAATATCCCAGTGAACGGATAGCCTCATAGGCACATCCCCAGGCGCTCGGCGCGCGGCTGGGGCCGGAGGGCGCGTGTTCCTGTTCCTGCTCACACCACAGATCCCCGGCATCACTGCCGCCAACGGTGGTTAATGCCTCATCGCTTCACGAGACTCACGCAGGCCAGCCCGAGTGCCCCGAGGACGCCGATCACCGCGAGGCCCCATCGCACCCAGGCAAGCCACTGGTCGGTGAGGGTGGCGAGTACGACCACGCACCACAGCGTCAGCACGACCAGGAGGAACGCGAAGACTACGATTCGGACTCCTTGCGTCAGCGGGGCGTCCCATAGTGATCTTCGGGCCGAATCTTCCCGGCGCATACCGCGCTGTCCCCTCTCCGTAAAAAACGACGGCTGGGAGGAAGACCGGCAGCGTCGGCCTCCTTCCCAGCGCCGTATAACAGTACATACCTAGTTACCCCACTCGGCGGTACGCAACGCCATTGCACGTCCGCCGCCGTGCCTGCGGTCCATGCCACCAGGAGCCTTCTGTGTGCAATCCCACACGCCTCTACAGCTAGGCACGATCCCATGTGTTCGGCGAAACGCCAACATCATGGGCGGGCAAGGCGTCCTGCCATGAACCCTGCTGCGCTGAGGCGAATCACAGCGGCCAGAGGTCGAGTCTCGAAGCTGACTCACCCGCTGTACTGATTGGCGGTCAGGACGCACGGGAATCCGCAAACTGATGTGCCATCAGGGCGTGTCTCCACTTCTCCAGCCTCTCGGTTCCCTATAGCCGTTGTTACGCCTGCCCGCCTTGAGCATGAGACGTCTGCGCTGCGGCGGCGCGGACCCTAATGGCTCCCACTGACAACACCTCGATCACCGCCTGAAGATCATTTTGCGTGCCCTGGCCTGCCCTGCTTGCATATCGGCCCCCTCGCCGTCCCTCTGGTGTCGGCGAGCCTCTTTTTGCCTGTCCATCAAGTAAGAGAAGGCGGCATGTCCTACCCGTTTTCCGTGGCCGATATCGGCTGGATTCCCGTACGGGTCCGTTCCGACCTGGACGCCGACGAGACCGCGGAACTGCGGTCCCTGTTACCAGAAGCCAGCCCCGGAGAATGCACCCGGGTGGGCCTGCGGCACCTCTTCCAGGGCGCCCATCTGTTCGCCGACCTCGACTTCGCGGTCCCTCCGGTCGAAGCCGTCGCGCGTCGCCTGCTCGCCGCGGTGACAGCACGGGTGGCGGGCCTGGATACCGGCACCTCGGCCCAGTGGCCTGACGCACGTGATGATCTCCTGGCCACCGGGCGGTTCGACGCGGACCGCGTGGACGAGTACCTGAAAGCCCACGCGCACCGTTGGAACCTGTACTACAGCGCTCAGCCGTTCCTCCAGGACATCCGGCTCGCGCAGGAGTGCGGCAAGGGGCAGGCGCCCGGCCGGCTGGTGATGGACCGTCCTTCGGGGAGCAACGCGGTGTGGACCACGCACATCGCCCAGGACGTGCCGGTGGCGGGGCCGGATGCGGTGCAGTGGCTTCTGGCCTGGTACGGATACGGCCCGTCCGGTACCGGCACGCATCGCACCCACGGCTCCCGTAAGGGTGGTTCCTGTAAGGCCGGGCCGTACCGCTCGCTCGTCTCATACTTCCCGCACGCGCCGGAGCGGCTGTTCGTGTCGTTGGTGGCTTCCGTGCCCGGTCCGTCGGCCTGGCCCACCGGTTCGGGCCCGGACCTGGCGCCGTGGGAGAGAGATGAACTGCCCGACCCGCTGGCCCCGGACGCGGCGTGCGGGCCAGTGTCGCTGCTGACCCGCCGCACCGCCCACGCGCTCCTGCTCACCGGCGACGACGCCGGGCAGACCACCAGCTGCAAGATCACCTGGAATACCGCGGTCGACCTGCCGGCCGCCGTCGACCCCTACGTCATCGAGCGCACCCAGGGCGGGCCGGTGCGCGCCGACCGGGCCCGCTCGGCCTGGCGCGACCTGGACGCCATGCTGCTCAAGACCCAGCCCGGCTCGAAGAGCACGCTGCGGCGCCCCACGGTCTTCGACGCCGTGGCCGAGCTTGCCCCGCAGGTCCAGCGTCAACTGGGGGTGCGGGTGCTGGCCTGGGACCAGGAGCGCCAGGAGAAGGACAACCAGTGGTACGCCGCCACCACACCCCCCGTCCTGCAGCACATCGAAGAGGCTGACCCTCAGGGCGCAGCAGCCATCGCCACCGCCCGGCGCAGTGCCGAGGCCGCCGCCGGCGACTTGGCCCGCGCCCTGGCGGCTGCCTGGCTCGACGTCCACGTCAAGCGGGATCCCCAACAGCGGCACGGCTTCGTGGAGGCGGCGCGCACCCGCTACTGGGAACGCGCCGAGGAGGAGTTCTGGCAGGCCGTCCGTGCCCCGGACCCGGACCGGCGGCCCGCCTTCCGCCGCCTGGCCCTCGAACGGTTCGACCAGGCCACCGCGACGCTGAAGGCCACCGTGCACGGGATGAGCGCGGTCGCCAAGGCCCGAGCCCAGCTGACCCTCCCCCGTACCCACGCAACCCGTTCGACCAGGAAGAGGACGCGATGAGCACCACGGCCGCCACCGCTGATACCGACGGCGCGCCAGCGCCTCCCCAATGGCTCGCCCGCCAGCGTCTCTGCCCCACGCACAACTTCACCCCGTCCGCGAGCCCCGGGCGGGCCGCCGGCACGGGTGCGCTACGTCGTGGCGTAGCTGAGGCGGAACAGGTCCTGGGCGCGCTCCAGGTCCCGCTCCGTGCGCAGTTGGACCTCCAGGTCGCCGGTGCCGTGGTGGCCCAGCCCCGTCACGTCCCGGGTCAAGCCGGGCACCAGGCCGGTCTCCTGCGGGTCGGCCTTGAGGTAGACGAGCAGCTTGCTCTTCTGCGGCGGGCACACGCAGGCGAAGTTCCGCAGCCGCCGGTACGCCCGGTAGAGGCGGTTCTCGGCCCTGGTGATGTCCGGCCCCAGGCCCAGCAGCGTCTCATCGACCGCGGCGGCCAGCTCCGCCATCGCCCCCTGCGACAGGTGCCCGCGCGTCGTGTTGGCCGCGCGCCGGCGACGGGCCGTCCCGGATGTCGCCGTCTGCCCCGTGACGGAGGCCACCGTCTCCAAGCTGACGAGTTGCTCGCCGTACAAGCGGTAGCGCACCAGGTCGATGCTGCGCCGGTGCTCGCGCACCGCGTGCACGTCGTAGCGGGTGAAGTCGCCCGCCACGCAGATCAGCCGCGGCGCGCTCCACCGCACCCGGGACGCGGCTGCCGCCCCCAGGCGCTCACGGACCAGGTGGCCGAACTCGGCCCGGTGGTCTATCAGCCACGCCAGGTAGAACAGGCCCTGGTTGATCACCCCCGCATCTGTTCCGCGCTTGTACTCGACGACCACCGGCGCGTCGTTCTCGTCCAGGCCCAGCGAGTCGATCCGTCCGCCGTGCACCGGCCCGGTGCCGTACTCGCTCGCCAGGAACCGCACGCCCAGCATCGTCTCCATGTGCGCCTCGATGAGGTGCTGCACGTCCGCCTCGACCTCAGCAAGACGCGGCGCGACCTCGGCCACGTTGCCGTTCATCGTGTGGAACAGCTTCAGCCCCGTCACCTTCCCCTCTTCGACTCCGCGACCTGCAACGCCTGCGAAGTGTCCGTTCTTCCCCATCGCTGCATCCGTGAGTCTGCGCTGACTGGGCAGTGAAGGGAACGCATTGCCTGGTGACATCCGGATCTGCCCAGCCTGACCTTGCATCTTCGGCTTGCCGGCGCCGCCGGCCTGCTGCCGGGTGTGTCATGTGGGGCCCGTCAGACCGGGTGGGTTGCGGTGGTCGATGATGTCGCGGGCGAGGTCGAGGATGGGGCGTCCGGTGGAGTAGGCGTGGGAGCGCAGCAGGAGCAGGGCCTGGTCGAGGGGGAGGTGGAGACGGACGGCGAGCATTCCGGTGGCCTGGTGGATCTCGGCGCGGTGCAGGGTGGCGAGGTCGGTGGCCGGATCGCGGCGGCCGTCGGCGCCGGGCAGCAGGGCCAGCAGTAGGAAGGTGGCGGTGTCGATGAACGTGTGCATGTCGAGGTGCTGCTGGAGGGTGAGGGGGCCGGGGCGGGTGCGGTAGCCGGTGAAGGCGCCGAGCCGGACGGCCCCGATGGCCAGCGGGAGGGCGAACAGGGCGCGGGCCCCGGCCTGCAGGGCCTCGGGCAGGAACGTGGGCCAGCGGGAGCCGGCGACGCGGGACAGGTCGGGTTCGGTGACCGTGCGGCCGTCGCGCAGGCAGCCCAGAGTGGGGCCTTCGCCGAGGGTGAACTGCACATCCTCCAGGGCCGTACCGAGGCGGTCGTCGGGGGCGGACCAGATGAGTTCGGGGGCGTGGCCGCCGGCTCGGGCGGAGATGGTGACGCAGGTCAGTCCGAGTGCCTGGGCGCAGCGGTCGGCGGGCAGCAGGCCCAGGCCCGGAGGGCTGCCCAGGGTGTCCAGGAGGGCGGTCATCAGCGGGCTGGCCGGGGGATCACGGGGGGGGAGGGCATCTGCCTGGCCCTTCCGGTGTGTTCGCGGGAAAGCGGGCTTGAGCTGGTGCTGACCGTTGCCGGGGCAGCGGGCGGGCCCCTACGCGGGTGGTGCGTTGAACTGTTCGGGATCGGCCTGGCCGTTGATGACCTGGTGGGAGAGGTCGGTCAGCAGGATCTGGTGGTGGCGGGCGCGGGCGCGCAGCCGGGTGAAGGCTTCGTCGGGGGTCAGGTCGAGGCGTTCGGCGAGCATGCCTTTGGCCTGTTCGATGACCACGCGGGTGCCCAGGGCGCCTTCGAGCTGTTCGTTGATGAGGGTCTGGTCGCGGATGGCGCGGTATTGCAGGATGCCGATGGTCGCGGCGTCTGCCAGGGCCTGGGCCAGGCGCAGGTCCGGCTCGCCCAGGGCCTGGGGGCGGGTGCGGAAGAGGTTGAGTGCGCCGATTGCGGTCTCGCGCAGGCGCAGGGGCACCGCGGCCGCCGCGGCGAAGCCGCGTTCGGCGGCCCATTCGGTGAAGCGGGGCCAGTGCTCCTCGGCCTGGTGGGTGTCGAGAGGGGTGTCGGGGATGGGGGCACCGGTGTGGATGCAGTCGCGGCAGGGGCCCTCCTGCCATTCGATCTGTGCCAGCTCCAGACGCCGGGTTTGTTCGTCGGAGGCGGTGGCGTCGACCATGCGTCCTTGGGCGTTCAGCAGGATGACCCCGGCCGCGTCCACCGGCAGCAGGCGGGTGGTGCGTTCGGTCAGGGTGTGCAGGAAGTCCATCACGTCGAACTCGGCGACCAGGGTGTCGGCGAGTTCGACGAAAACCGAAGTGATCTCCTCTACGCGGGAGAGCCGTTCTTGCTCAGCGGTCATGACACTCGCTCCCGCCCCTTCCTTCGGGGATATGGCGTGGTCGTGCCGGGGGGGGCATGGTTCAGCGACAGCCCGGTACGGGGTCGCGTCTTCAGCGTGGCACCGGCACGGACCGCCGCCAATCCCTGGGCACAGCTTTAGCTTTCGGCAGCGATGCGCATGCACGCCGGATCCGTCGCGGACTGCACTGCCCGGCGGCCACCGTCGCCGGCCTTTCCCGTCTGGCGCTGTCCCCGTGCGTCGGCGCGGACGGCACGTCATACACGCCCCGGCGAGCCGCCGTGGGTGTGTGCCGCGATCAGGCTTCCTTGCGTCGGCGCGGGGCCGCTCGCTGGATCCGCATGAGCCGGCAGTGCTCGTCCAGCAGCCGCCGGTTCTCCTCGCTCGCCGGTTCTCCTCGCTCACGGGTCGGACCGTTCTTCGTAACTCGGCCGCCCGTTCCCGAGTCTGCTGCGCTCGCTGCCGTACAGCCTCCACCGCCATACCCCGACTGTTCCAAGCAGCGCTGTTCTGTCGACCACGACCACGGACTCTCCGGCGACATCGGTGCCGTACCTCGCCTTCGCCCGCGCGGCCACCGCCGGTCGGATGGAACCGGGTGCCGGGCGGGGTGGCGTGTCAGGCGGGGCGGGACGTGGTCGGCGAAGGCGCGGAACAACGTTTCGATGGCGTCCAGAGGCAGGGCGTGGTCCACCACTCCGGCATCCACAGCGGCCTGCGGCATACCGGGGAAATCGGCGGTGGCCACCGATGTCTGCTCATGGGTGCTGTGCCGGGCCGGTATTTCCAGCTCTGGTCAGCTCGGCAGAAGCTGCCGCTGCGGCAACTACAAGGCTGGTGGCCACGCTCCGGCCTCGACTCCGCCGCGGACGGTTCGATGCCGAGCGGGTTCCGAACCGGGCCCGCACACCCCGCATGACTTTGAGGCATCACTGGTTTCACTTTTTTGATAAAGGAATAGAAAAAATGCATCCCGTCCGTGGAGGTCGTGGCTCGCAGTGGGCCGTGTGACGAACTGAGGCGAGCCTCTCCTTCCGTGGCGGTCCCCGCTACACCTCTTTGCCACCCATATCCGAACGCCTGACTTTCACAGCCGCGCCGTCCCGCTCACTACACATCTCCGGCGATGTATATACCCCGCGCCATACAAGCAAACGCTGCTCGCATATGCGCGCGGCACGTAGAGTAAAGAAATGGGAACGTTGCGTATAATTCTGCCCAATTGTGTTCTCCGAAGCGGTTGAAAGCGTGATCTCGGGGTCAGGATGGGGCCGGAATTGCGCCCTTGCCCGCTGGCAGGCCACAGGGTGCCGCTGCATGGGGAGAGGAGACGTCCGGACGTGACGCAACGCGGAACACGCAAGGCAGCGGAACGTATGGCGGGTGCGGCGGCGGAACGGTTGCTGCGGCTCGGCCGGCAGTTGCAAGGGGCCGCCACAACACCGGACGGGCGCGCGGTCTACCGCACGGACCAGCAGGTCAACGACGCTCCGTACCGTGAGCGGTGGGCGCACGACAAGGTGGTGCGCTCGACCCACGGTGTGAATTGCACAGGCTCGTGTTCCTGGCAGGTGTTCGTCAAAGACGGGCTCATCACCTGGGAAACACAACAGACGGATTACCCGTCGGTGGGCCCCGACCGCCCGGAGTACGAGCCGAGGGGATGTCCGCGCGGAGCGTCCTTTTCCTGGTACACGTACTCGCCGACGCGGGTGCGTTATCCGTATGCGCGCGGCGTGCTGGTGGAAATGTTCCGGGAAGCGCGGGCCCGGCTCGGCGACCCGGTGGCGGCCTGGGCCGAGATCACCGGGGACGCGGCCAAACGCCGCCGGTATCAGCAGGCCCGCGGCAAAGGCGGCCTGGTCCGCATCGGCTGGGACGAGGCTTTGGAGATCGCGGCCGCCGCCCATGTCCACACCCTCCAGCATTACGGGCCGGACCGGATCGCCGGCTTCTCCCCCATCCCCGCGATGTCCATGGCCTCGCACGCGGTCGGCGCCCGCTTCATGGCCCTGCTCGGCGCGCCCATGCTCTCCTTCTACGACTGGTACGCGGACCTGCCGATCGCCTCCCCGCAGGTCTTCGGCGACCAGACCGACGTCCCGGAATCCGGCGACTGGTGGGACGCGGCCTACCTGATGCTGTGGGGCTCGAACGTGCCGGTCACCCGCACCCCGGACGCGCACTGGATGGCCGAGGCCCGCTACCGCGGCCAGAAAGTCGTGGTGGTCTCCCCCGACTACGCCGACGCCACCAAATTCGCCGACGAATGGCTGCATCCCCACCCCGGCACCGACGGCGCCCTGGCCATGGCCATGGGCCACGTCATCCTGCGCGAATGCTTCGTCCAACGCCAGGTCCCGTACTTCACCGACTACGTCAAAACCTTCACCGACCTGCCCTTCCTCGTCGAACTGGAGCCGCACGGCGCGTCCTTCGTGCCGGGGAAGTTCGTCACGGCGGCCGGCCTGGGCCTGTCCGAGGAGGACGACGGCGGGGAGAACGGGCAGTGGAAGCCGGTGGTTTTCGACGCGGGGCGGGGTGCTCCCGTGGCTCCGCCCGGCACGCTGGGGGAACGCTGGAGCGAGGGCGGCGCGGGCCGCTGGCATCTCGACCTGGGCGACGTGGACCCGCTGCTCACCTTCCACGAGGCGCAGGGCGCGGCCAGTGTGGAGGTCCTTCTTCCACGCTTCGACCAGGGCGCGGAAGGTGAGGCCGGCACCGTGCGCCGGGCGGTGCCGGTGCGCGAACTGGGCGGCCGCCGGGTGACGACCGTCTTCGACCTGCTGCTGGCCCGGTACGGCGTGCACCGTCAGGGTCTGTCGGGGCAGTGGCCCCAGGGGTACGACGACGCAGCGCTGCCGTGCACCCCGGCCTGGCAGGAGACGCTGACCTCGGTTCCGGCGGGCGCCGTCGTACGGGCGGCGCGGGAGTTCGCACACACCGCCGAGAAGACGCGCGGGCGCTGCATGATCGTGATGGGCGCCGGTACCAACCACTGGTTCCACTCGGACACCATCTACCGGTCGTTCCTGACGCTCCTGCTGCTGACCGGCTGCCAGGGCGTCAACGGCGGCGGCTGGGCGCACTACGTCGGCCAGGAGAAGGTACGCCCGTACGCCGGGTGGCAGCAGTTGCAGAGCGCGGCGGACTGGGTACGGCCGTCGCGGCAGATGGCCGGGACACCGTTCTGGTACCTGCACACCGACCAGTGGCGGTACGAGTCCTACCGCGCCGACGCGCTGGCCTCCGCGACGGGTCGCGGTCTGTTCGCGGGCCGGCACACCGCTGACCTGGTGGCGCAGTCCGCCCGCCTGGGCTGGATGCCCTCCGCCCCCACGTTCAGCGACAACCCCCTGACCCTGGGGGAACGCGTCCGCGCCGCCGGGAGCGAACCGGGGCAGTGGGTCGCCGGCCAACTCCGGGACGGGCAGCTCCGGTTCGCGTGCGAGGACCCGGACGACCCGGCGAACTGGCCCCGGGTGCTGACCGTATGGCGGGCCAACCTGATCGGTTCCTCCGCCAAGGGCAACGAGTACTTCCTGCGGCACCTGCTGGGCGCCGACGACAACGCGAGCGCCGAAGAAGCGCCCTCCGAGGCACGTCCGCGCGATGTCACCTGGCACGAGGAGGCGCCACGCGGAAAGCTCGACCTGCTGCTGGCGCTGGACTTCCGTATGACCTCCACGACCCTGATGGCGGACCTGATCCTGCCCGCAGCCACCTGGTACGAGAAGCACGACCTGTCCAGCACGGACATGCACCCGTACGTACACGCCTTCTCGCCCGCGATCATCCCGCCCTGGCAGGCCCGTACCGACTTCGAGATCTTCCACGGCCTGGCGTCGAAGCTCAGCGAACTGGCCCGTGGGCGCCTGGACACCCGCTACGACCTGGTGGCCACCCCGCTGACGCACGACACACCCGGCGAGACGGCGCAGCCCGGCGGAACGGTGCCCGACTGGCGGGAGGCGGGTCGGCCTCAGCCAGGACACAACCTGCCGGCGTTCGCGCTCGTCGAGCGGGACTACACCGCCGTGGCCGCGAAGCTGGCGAGCCTGGGGCCGCTGGCCGAGGAGGCGGGCATGACCGTCAAGGGCGTGACCGTGTACCCGCGGGCGGAGGCCAGGTGGCTGGCGGACCGGTGCGGGACGGCCGCCGACGGCGCGGCGAGCGGCCGCCCGCTGCTGGACACGGACGTGAAGTTCTGCGAGGCGATCCTCGCCCTGTCCGGCACCACCAACGGGCGGCTGGCCGCCGAGGGGTTCGCGCGCCTCGCCGAACGCTGCGGCCCCGACAGCGGACTGGAGGAGCTGGCCGCCTCGGTCGCCGAACGGCGCATCGTCTTCTCCGACACCCAAGCCCGCCCGGTGCAGGTGGCGGCCAGTTTCGAGTGGTCGGGCAAGGAGGGCCCCGAGCGCCGGTACGCGCCGTTCACGATCAACACCGAACACCGCAAGCCCTGGCACACCCTCACCGGCCGCCAGCACTTCTACCTCGACCACGACTGGATGGCCGAACTCGGCGAGCAGCTCCCCGTCTACCGGCCGCCGCTGGACCTGGCCGCACTGGGCGAACACCCTCCGATGGCGGGAGTGGAGGGCGCGCGCTCGGTGACGGTCCGCTACGTCACCCCGCACTCGAAGTGGTCCATCCACTCCGAATACCAGGAGAACCTGCTCATGCAGACACTGGCCCGCGGCGGCCCGGTCATCTGGCTCAGCGTCCAGGACGCGGCACGTATCGAGGTGGCCGACAACGACTGGATCGAGGCGGTCAACGCCAACGGCGTGGTCGTCGCACGGGCCATCGTCTCGCACCGCATGCCGCCCGGCACCGTGTTCATGTACCACGTACAGGAACGCCTGGTGAACGTGCCCAAATCCCAGGCCACCGGCCGGCGCGGCGGAGTGCACAACGCCCTCACCAAACTCCTGATCAAGCCCACCCACCTGATCGGCGGCTACGGCCAGCTGTCCTTCGCCGCCAACTACTACGGCCCCACCGGCAACCAGCGGGACGCGGTCACCACCATCCGGCGCCGCTCGCAGAACGTGGAGTACTGACATGCCTCGCGGCACACCCCCCACCCGCCGGGTCATGGCCCAGGTGGCCATGGTCATGAACCTCGACAAGTGCATCGGCTGCCACACCTGCTCGGTCACCTGCAAACAGACCTGGACCCACCGTTCCGGCACCGAATACGTCTGGTTCAACAACGTCGAGACCCGGCCCGGCCAGGGCTACCCCCGCGCCTACGAGGACCAGGAGCGCTGGAAGGGCGGCTGGCGGCTCAAGGGCGACCGCCTCGTACCCCGCAGCGGCGGCCGGGCCCGTCGGCTGGCCCGTCTCTTCGCCAACCCCGAACTGCCCGCCCTGAGCGACTACTACGAGCCCTGGACGTACGACTACGCGAACCTCACCACCGCGCCCCTCGGCGACGACCTGCCCACCGCACCGCCCCGTTCCCTCATCGACGGCCGCCCCACCGACATCACCTGGGGCCCCAACTGGGACGACGACCTCGGCGGCGGCCCCGACCACCTCGCCGACGACCCCGTCCTGAAGAAGATGAACGAACGGGTCCGCCTCGAATACGAGCAGGCCTTCATGTTCTACCTCCCCCGCATCTGCGAACACTGCCTCAACCCCTCCTGCGTCGCCGTCTGCCCCTCCGGCGCCCTCTACAAGCGCATCGAGGACGGCATCGTCCTCGTCGACCAGGACCGCTGCCGCGGCTGGCGCATGTGCGTCACCGGCTGCCCCTACAAGAAGGTCTACTTCAACCACCACACCGGCAAAGCCGAAAAGTGCACCCTGTGCTACCCGCGCATCGAAGCGGGCCAGCCCACCGTCTGCTCCGAAACCTGCGTCGGACGACTGCGCTACCTGGGCGTCATGCTCTACGACCCCGACAAAGTCGGCGAAGCCGCCCGCGTCACCGACGAAAAGGACCTCTACGAAGCGCAGCTCACCTGCTTCCTCGACCCCACCGACCCCGGCATCGCCCGCGCCGCCGAGGAATCCGGCATCCCGCACGACTGGATCACCGCCGCCCGCCGCTCCCCCGTGTACGCCCTGATCAACACGTATCGCGTCGCACTGCCCCTGCACCCGGAATACCGCACCATGCCCATGGTCTGGTACGTGCCGCCGCTGTCCCCCATCGTCGACTCCCTCACCCGCACCGGCCACGACGGCGAGGACCCGGCCAGCCTCTTCGGCGCCATCGACGCGCTGCGCATCCCGCTGGACTACCTCGCCCATCTCTTCACCGCGGGCGATCCGGCGCCCGTCGAAGCCGCCCTGTGCCGCCTGGCCGCCATGCGCGCGTACATGCGCCGCATCAACCTCGGCGACCCCCGGGACCCCGCCATCGCCGAGGCCGTCGGCCTCGGCGCGGACTCCATCGAGGCCATGTACCGGCTGCTCGCACTGGCCAAGTACGAAGACCGCTACGTCATCCCCACCAGCTACACCGGAACGGTTCCCCCGGACACACCGGACGACGGGTGCAGCCTGGACGCAGACGGCGGCCCAGGCATGTACGACGCCGGCCTCCCGGGCATGGAAGCTTTCCACACCCCGCCGGCCACGGAACCGGCACCGGCCGGCGACGGGCTGCGCGGCCGCGTCAACCTGCTGAACTGGAACGGCCGAGGCACGCCCAGCGGTCTGTTCCCCCGCCGCCGGGAGAACGAACGGTGACCACCCTGCGTTCCGCCGTCCACCAGGCAGCCTCCCTCCTGCTGTCCTATCCCGACGGCGACTGGTCCGTACGGCTGGCCGCCGTGGCCGAGACGATGTGCCCGCTGCCCGGCGAGGCGCCAGCCGCGCTGCTGCGCTACTGCGACCACGCCCGAGGCGTGCCACTCCTCGACCTGGCCGCCTGCTATGTCCTCACCTTCGACCGCAGCCGACGCCGCACCCTGCACCTGACGTACTACACCGACGGCGACACCCGCCGCCGCGGCGCAGCCCTCGCCCGGCTCAAAGCCCTCTACCGCACCCACGGCTGGCAGCCGAGCGACGGCGAGCTGCCCGACTACCTCCCCGCCGTACTGGAATTCGCCGCCCGCTGCCCCGAGCCGGGGCTGCGCCTGCTGCGCGACCACCGCCCGGCCGTCGAACTGCTCGGCCACGCCCTGGAGAAGCACCGGAGCCCGTACGCCGACGTGCTGCGCGCCGTACGCGACACTCTGCCCGCCCCTGCCGCTGGGGACCGCGCCGCCGCTCTCGCCCTGGCACGCACCGGCCCGCCCTCCGAGAACGTAGGGCTCGACCTCTTTCCCGCCGACGCGTCCGCACACAGCGAAGGAGCCCGCAGGTGACTCACGTGCACATCGCCCTGTGGGGAGTGCTGCCCTACCTCGTCCTGGCTGTCCTGGTCGGCGGCACCGCCTGGCGCTACCGCTACGACCGCTTCGGCTTCACCACCCGCTCCAGCCAGCTCCACGAGTCCCGCCTGCTGCGCATCGGCGGGCCCCTCTTCCACTACGCCCTGTTCCTGGTCATCGGCGGCCATGTGACGGGACTGCTCGTGCCCGAGTCCCTGACGGAGCATCTGCATGTCAGCGAGACGATGTACCACCTCTTCGCGCTGGCCGTGGGCGGGACAGCAGGCATCGCGGCCGTAGCGGGGCTGGGCATCCTGCTCTACCGCCGCCTGCGCGTGCCGGCTGTACGCGCCGCGACCAGCCGCAGCGACCACCTCGTCCACCCCTTGCTGGCCGCCGCCCTGCTGGCCGGGCTGGTGGCCACCGCCTCCAGTGCCACCAACCCCTACGACTACCGGCTGGGCGTCTCCGTCTGGTTCCGCAGCCTCTTCGCCCTCGACCCCGACGTCGCTGCCATGGCCCAGGCACCGTTCACCTACCAACTGCACGCCCTGCTGGGCATGGCCCTGTTCGCCCTGTGGCCCTTCAGCCGCCTGGTCCACGCCTTCACGGCACCCCTCGGCTACGTCATCCGCCCCTACGTCGTCTACCGCTCTCGCCGCGGCGTCGGCGGCCGCGGCCCGTACCGGCCAGGCACCCCGTCCCAGGCCCCGCGGGTGGATCACCCGGCCCGAAAGGCCGCCCCGACGCCCGGCCGTACGGCCCGCCGCACCCCCGGGTGACACCCGGACCGGACGCTGCCGGGCCACCTGCCTGGCTGCAACGACGATCACGAACCCACCAGGCGGCCAAGCCGATACCGCGTGCGGCCCACAGCCCCAAGCAGTTGCTGGAGCATCCATGGGCCACCAGGCCACCACCACAACGAACAGCTACCGGGCGCGCATGCGGGAAGGCATCGGGCGTCTCCCCTCGGCGTGTTTCGCCTCCGTCATGGCGGCGGGCATCGTCTCACGGGCGGCCGCGTCTGTCGGTGCCCATACAGTGGCCCGACTGCTGCTGAGCCTGGGCGTACTTCTCTACGTGATGCTCGTCGGAGCGACCGCGTGGCGGATCGCCGCGCACCGCGGCCGGGTGGCGCAGGACGCCGCAGACCCGGCCCGCGCCTTCGGATTCTTCACCTTCGTGGCGGCATCCGACGTGCTGGCCACCAACCTGGCCACCGGCGACTGGCGCCCCTTCGCCATCGTCCTGCTGACCGGCGGTGCCCTCTGCTGCGCAGCGCTCCTGCGCACTGTCGTCACCGCGGCCCGGAGCCGGCCGGCGCGGGCTGACGGCAGCTGGTTCCTGCTCGTGGTCGGCCCGCAGTCGGTCGTCGTGGCCGCCACGGAACTGCGGGCCGGGCCCGCCACGGCGGTGGCGGGCCTGTGCTGCTGGGCGGTGGGCGTACTGGCGTACGTCACGATCACCTCGCTGGTCTGGACGCGTCTGCGACGGCACGGCGTCCCACCGGCGGAACTGACTCCGGTGTACTGGATCGCGATGGGAGCGGGAGCCATCAGCGTCCTGGCAGGAGCTGGTGTGCTGCTCTCCGCCTCCTGGTACGAGCCGGTCAGGACAGTGGTCACCGCGGTGCTCATGTTGGTGGCGGGCTGGGCGACAGTGCTGATCCCCGTACTGCTGGGTGCCGGCGCGTGGCGGCACATCCGGCACCGGGTACCGCTGCGCTATGAACCGTCCTGGTGGTCCGCCGTTTTCCCGATCGGCATGTACGCCGTGGCCACACAGCAGGCAGCGCGCGCGACGGGTGCCGGCCTGTGGGAGAAGGCGGGGCAGGCTGCGGCGTGGGCGGCACTGACCGCATGGGCACTGGTCGGCACGGCCATACTCGCCCAGTGGCCCCGTTCCGGGCCCACGTCGCTGCGCGGCAGGAGCCGCCGACCGCCGGCCGGTTGACCTTCTCCGTACCCGGTCGCCGTGAACGCGGTCCTCCATCAGAACCGGCCGGGCCGCCCGTAGCGCTATCCGCCCATGGTCCCCCACCCGGTCAGCGGTCCTCTACTACTGCACGCTGCGGCACGGACGGCCACGAAGCATAGGTAAAAGCGAAGCCAAAGCTCCTGTCAGCTCGGGGGATCCTTCGGTGCGGGTACGGCGCCGGCGGTTTCCGGCACGATCTCGGGCTGCTCGGCCAGGTTCCGGCGGGCTGCGCCGATGGCGACTGCGGCCAGTACGAGGGCGCCTGCCCCGAAGACCGCGTTGCCAGCCAATCCGATGGCCGGCGGGACACCCATGTCCGCCGCGTGGGTGAAGCCCAGCCAGACGTAGGTCAGCAAGGCGCCGACGGCCACCGCGACACGGTGGCGGCTCCCCCAGCCACGGCGGCGCGACCAGCGGCTGCCGGCAGTCACGGCCGCCACGGCCAGTGCCGACCAGAGGACGACCAGGAGCCAGTCGGAGACGCGGTCCCGCAGCAGCGACTGGCCGGCCCAGTAGGCGCTGGTCAGGAGGAAGGCCACTCCGCCCACCTGCCACGGGCCGGGAGCAGGGGCGGGGGCACGGGCCGGGCGCCTGAGTCCGCGGCCGGTGTGGAAGGCCACGACGACCAAGCCGACGATCATGACCGTGCCGGTGGACCACTGCCATGCCGAGGCCAGGAACCGGTCATTGTAGAGATATTGCAGGCAGGCCAGGAACAGCGAACCGGCAGCGAACACCAACACCGTCACACTCATGCCCGGCCGCCCCAGCCAGGGCCGCCGCGGGTCACGGCTGAAAGCTTCGACGAGCGCGATCGGTACGCAGATGCTCCAGATCATGTGCATCGAGACGACGTCCTGGAGCAGGGACAGGCTGGTGCCCAGCAGTGGCACGTGGGTGCCCGCGTAGACGAGGCCGAAGTCGGCCGTACCGTAGTGGGGATTCCACAGCATCTGGTCGACCGGCCCCTCCTCGAACAGCCCGTAGGCCGCCGCGAGCAGCAGCATCGTCGGCCAGCCGCGTCCGGTGCGCCGGGCGATTTCCCTGATGAGCAGGGCTGCGCACCCGTACAGCGGAAGATAGAGGAACAGCGCTCCCAGGTCGCTGATCGGCGTGTTGCCCAGGAGGTACTCGCCCACCAGCGGGGCCAGGAGGACCAAGGCGAAGGCTGAGCGCCACCGGTGCGGCGTTTCCCGGACATCGTGCATGCGTACGACGCTAAATCGGCCCCCTGACCTGCGCCTCTGCCATCCGGCCAGAGGTGTCGGCCACCTGGCCGGACGGCCTGCGGGAAAGCCGGGCAGCCCGATGGCAGCACACCCGCGAGCCGGCCGCCGGCCGCCCGGTGCGCTATTCGGCTTGCGCGTCGTGGGCCAGCAGGGCCAGCTGGATGCGGTTGTCGAGGTCCAGTTTGGTCAGCGCACTCGACAGATGGGCCTTGACGGTGCCGGTCGACAGGTGCAGCCGCTGTCCGATCTCGGAGTTGGACAGCCCTTCGGCCACCGCGCCGGCGATCTGGCGTTCCCTCTCGGAGAGTACGGCGAGCCTGCGCCGTGCCTGCTCGGTGCGGGCGCCGGCCCCCGCCGCGGCATGGTCGATCAGGGCGCGTGCCGCCGTGGGGGAAAGGGCCGGTGTGCCGCGGGCTGCCTGGCGTACCGCGTCGACGATCTCCTCGGGCCGGGTGTGCTTGAGCAGGTAGCCCGCGGCCCCCGCACGTACGGCCTCCAGGATGAGGCCGTCGGTGTCGAAGGTGGTCAGCACGATCACCTGGGGCGCCTGGTCACCGCCGGCCACGGCGCGGGTCGCGGCGATGCCGTCCATGCCCGGCATCCGGATGCCCATCAAAACGACGTCCGGGCTGTGCCGCCGAACGGCCTGGGCCACGCCCGCGCCGTCCTCCGCACCTCACCCGCAGTCTCCTCGGCATCCCGCCCCCTCCGCGGCGGACGCTCACCTGGGACCGGGGCAGGGAGATGGCTGAGCACCAGGCCATCACCGCACGGACCGGGATGCCGATCTACCTCTGCAAGCCACGCAGCCCGTGGCAGCGCGGCACCAACGAGAACACCAACCGGCTGCTTCGGCAGTACCTCCCCAGGGAGCGGACCTCCGCACGTTCAGCCAGACCGATCTGGACACCATCGCCCACGAACTTAACCATCGTCCACGCAAGACGCATGGCTATCGCACTCCGGCAGAGGTTTACGCTGACCTCCTGAACAGCGGTGATGCGCTGACCGCTTGAGCTCGGCACCGCTAGGCGCCTGGCTAGTGTTCGAGGACGAGGCCGGATCCGTGATGACTCCGTCCACCGCCCGCCCTTGTTCCCGGTGCGATCGAACCCCTGTCGTGCGGGCCTGCGCACGCTCCCGTCGGCGCCTGCCGGTCGCGCTTGGGAGCCGGTGTCACGTCCGTGGACGTGCCGCGATGCGTCATCGCTCGATGCCGCAAGACTTGAAACTGACGCAGCGGCAACGTGGACGATCGCTTGGTACGGCACGTACGGCTCACCCAGCGATCCCATCCGGAGGCACCTGTCATGCTGCGCGGCAAAGGCATTCACTACGACACCGGCACCTTCCCCAACGGCGACACCTCGCGCCCCGTCTTCGACCCACGGGACGCCGAACGGGACATACAGGTCGTCGCCGAAGACCTGCACTGCACCGCAGTCCGCATCACCGGCGGCGACCCCGACCGGATCGAGACCACGGCGCGGTACGCGGCGCAGGCCGGACTGGAGGTCTGGTTCTCACCGTTCCCCTGCGAGCTGACCAACGCCGAGATGCTGCCCCTGTTCGCCGACTGCGCCGAGCGGGCGGAGCGGCTGCGGCGCGACGGCGCCGAGGTCGTCCTCGTCACCGGCTGCGAACTCAGCATCTTCGCCCGCGGCTACCTGCCCGGCGACATCTTCAACGAGCGCGTCCCGGTGCTGGCGGGCCCCGGCCGCGAAGCCGCACTCCGGGGCATCCCCGACAAGGTCAACACCTTCCTGGCAGAGGTCGTCGACACCGTGCGGCCGCTCTTCGGCGGTCGCATCAGCTACGCCTCCTGCCCCCTGGACGGCGTGGACTGGACCCCGTTCGACATCGTGGGCCTGGACGCCTTCCGGGGGCAGCGCAACGCTGCCACCTACCGGGCCGACCTGCGCGCGGAATGCGCCCGAGGCAAGCCCGTCGCCGTCATGGAGGCCGGCTGCTGCACCTACCGGGGAGCAGGAGACCACGGCGGCGCCGGCTGGTACATGGCCAAGGAAAGCGACGGCATCACCCTCAGGCCCGGCCTCGTGCGCGACGAGGGCGAGCAGGTCAGGTACCTCGAAGACCTCATGACCGTCTTCGAGGAGGTAGGCGTCGACTCGGCCTTCTGGTTCAGCTTCGCCGGCTTCAGCACGCCCCACCGGACGACCGGGCCGGACGAGGATCTCGCCTCCTACGGCATCGTCAAAATACTGGATGAACACAGTGATTACCCCGTCAGCCAGCGCACCTACCCGGATATGCCCTGGGAACCGAAGGAGGCGTTCCACGCCCTCGCCAGACGCTACGGAGCAGATGGCAAGTAGAGCAGATCCTGCTGCCGGGCACGCAGGAAGCCGGCCAGCAACACAGCCGTGTGCGCGTAGGCCTTCATCGACTTCGGATCCATACGGCCCATCGCCAGACGGCGGAACCAGGAGCACAGCGGCTCCACCGGACGCATCGCCTCGCCCAGGAGCAGCGGCATCCCGCCGGTACCCGGCGACGCTCGAACAGCGACCGCAGCTGGCCGTGGTCAAGGCCGGCGACTTCCCCGGCCCACCAGACCTTCCGCTTGTCAGTGAAGAACAGCAGCACCTGGCCTCCCTGAACCCGCCCGCCACACGGCTGGCAGCAGCTTCACGGCAGCAAGGCCGTTATCAAGCACCTGCGGTGAAACACATTCTCGTGTTGGCAGAACCGTCGGCCTTGGCCTCAAAGCTCCACCCCGGGCCGGTGCGAACCTGGCTGGCGGGGCGGGCCCGCGCGAGGTCGGCGGGCAGCGGGAACGGCGGCACGTACCAGCCGTACCCGTGGTCGAGTCGGCCCGGTCGCCGTGCCGCCTCAGACCACTCCGCCGCACCACAACAACCAGATCAGCCTGGACATCCGAGCCATGTTCGTCCCTCAGAGCTCTGCGTAGGCTGACACCGTTGCATCAGCCTCGCCAGGGTCGCAAGGACCACTGGGGCACCACAGTGTCTCCGTAGCCGCGGCCGCGGTATCCGCCTCGGCCCGGCGAGACGTCCGAAGTGGGCCCGCCCCACTGGCGGGGATGCCGTTCACGTGAGGTGGAGGGTGGCCAGGGCAGTGGTCCAGTCGGTGGAGATGGCCTGCTGGACCCGACCACGAACGGCTGCCCGAGATGAGCGAATCACTGATCACCTGGGCCTGCATCACCCTGATGACCCGGCGGCTGACCCGCCGCCAGGCCCGGCCCGCCGAACGCCGCGACGCCGCCCACGGCTACGTGATGACTCAGGCCCGCCTGATCTCATCTGGATGCGCCGCCGGCCCCTCCCGCCTGCGGCCCGGGCCCTTTTCCCCGCCCCGCCGGACGCATCCGCTCCACCCAGGCGAACCCCGCCAGGATCTGCGCAGGGGACAGCCCCGTCTCCTGTTCCAGGACGCGCGGGCTGACGCCTTGCGGATGCTTCATCACCGAACGGACGATCTTGCCTGCCCACAGCTCCTCGCGGACGAACGGCTGTCGGCCGAACCGTTCCTGGATCTTCTCCAGGCACTCCGGCGAGCAGAGCATCACCAACCGCTTGCCGTCGTTCGTCGGGTCCTCATAGATCGCTGAGGAGTCCGGCAGCGCCGCCAGCAGCGGATCGTCCCCGTCGAACAGGTCCGGCTCCATGATCTTCCCGCACTCGTCGCAGTCGATCAGGCCCACGAAATCGTCGTCGTCTTCATCGGCGAACTCGTCATCGGGTAAGTCAGGTTCCATACCTGGAGCCTGCCCCGCCGGTGGGTTCCGTATCGGCCGTCTCCCACGGCGGCCGCAGGCTCGGGTGCGGCCCCGGCTGCGTACTCATCCCGTCACAGGGCACCGGGGCCTGACCCGCACACCCCATACCGGCGCAGGCCGCAACCGAGCCTAGTGCCCCCGCAGAAGGCGACAGCACCAAGGGCCTCACCGACACGCCAGCCCGGACACTGACCGCAGCCAGCTTCAAGATCCACATCAGGGCTTCAGGCACAGACTGTAAACTTGTTCCTTAACCACGGATCTGGTCGTTCGGTGACTCTCCGAAGTGATGGACGGGTAGGTGGCCCGTCCTCCTCATGGCCCTGAACCCTGTCTCTAGGTAAGCGAGTTCGTGGTGGAGGCCGTGGGGATGAGTGAGCTGGTGTGGGCCGGCGGACGGGAGGCCCTCGCAGAACTGTCGCGCTTCCGGACGGCTTTCTATGAGTGTCTGTCCGCGCGGGCTTATGCGTTCTTCGAGCTGACCGACGCGTTGCGGTGTGTGGACGGCCCGACGCGGACGCCGGTGGAGCTGTCACTGCTTGCCGAACACCAGCGCGGCTACGGCTCGCTGTACGGCGCCCTCAATCACGGCCGGCTCGACACCGAGGCCCTGCGTGACCTGCTGGCATCGCTGCCGATGCCGCGCTTCAAGGGATGGATCGTGCTCGCCGTGGGCGTCTCCCCTGGCTGCGCTCGGACGCGGCTTTCCCCCAGGCGCTCGTCGAGAGCTTCCGAGTGCTCCCCGTGTTACCGGAAAAAGAACCCGGTCGAAAAGGTGTGCCCCGAATTGATGCGCGGTCCGCCTCCAGGGCGAACATCGCAGCGGCCCAGACGGGAAATATCAGCAGTACCAGCACGCTGGTCAGCAGGACGTTCCACGTGCCCGGAGAATGCCAAGCCCCGGCTTCACATGACACCGCCGGTGTACGGCGCGTGCATGGCGCGAAAACAGTGCACTGTATACGTCAAGATTTTTCCATGGCCTGGCCAGCTCACGAATGTGTGCCCGCCGAAGGACCAGCCGGAAAGCGCCGGAGCCGGACAGAAGCCGGTGTTCGATTTGCGGAATGTTGACGTCGCCATGCGAACCCCCCGCAGGTGACCGCACCTCTCCAGAAGCAGCTGTCCATGGACATCCTTCCATCCGCTTCATCCGCGTCGAACAAAGGCTGCCGATGTCTTCGCCCCTGCTCGGGTCCGTGTACGGGCCGGCCGACCCCGAACCGCCCACCGTCGCGCCGCCCGACGGCCCCGCCATCTACCGGAGCGCCCCCGCGGCATCGCCCCGTACCCTGCTCGACGTGCTGGACGCCACCGCGGCGCGCCACCCCGACGCCGTGGCCCTCGATACGGGTGACACCCGGCTCGACTACCGGTCCCTGTGTGCGCCGAGTCCGAGCGGCGGGCACGGGCGCTGGTCCGGTGCGGGATCGGGCCCGGTGACCGGGTCCTGCGGCTGGCCGAGCCCGGACCGCGCCGCATCTTCGACGACCGAGTGTACGTACGCGGCGCCTGCACCCTGCACGCCCTGCGGCTCACCCTCGACGGCGACGCGCGGTTCTTCGCGCTGCTGCGCGGCTGGCACGACGCGCACCGCGGCGGGAGCTGCGATACCAAGACGTTCCTGGCCCACGCCGAGGCGGTCGCCGACCGGCCCGTACGGCCGCTGCTGTGCCGATGGCTCTCCGAGCCACGGCTGCCGCCGCTCCCGCCAAGGCCGTCCCACTGAGCCCGATCCCCGGCGGAGCCGAAGACCGGTCGATTCCACCTGGCGGCGGGACGACCGGCACGGCCCTCCTGCCACCCGCACGATGGAGCGAGAATCCGTACGCATCGGAAGGAGCCGTATGGACGCGCCTCGCACCGACGGCACACCTGGTACAGACACACCACGCATGGCCGCGCCGCTCCCCCTCTTCGGGTGGCTCCGTCCAGTCCCGCCGTGGTCGCCCTCGCCTATGCACTGATCCAGGTCATTCTCGTACTGCCGCACACCCGCGACGGGCTCGGCTGGGACGAGACGGTGTACGTTTCCCAGAGCGACCCGCGCACACCAGCCGCCTACTTCAGCGCCCCGCGCTCACGCGGCATCAGTTTCCTGATCGCACCGATCCTCGCCGTCTCGCCCTCCGTCACCCTGCTGCGCACGGTGCTGGCGCTCGCCTCGGCAATGGCTCTGTACGGCGCGTTTCGCGTGTGGACGCCGCTGCTCGGCCGTCGTACGACCGCACTCGCCGCATCGCTGTTCGCCGGCTTGTGGACCACCATGCTCAACGGCTCCCAGGTCATGCCCCAATTTGTGGGAGGCACTGGCGGTCGTCGCGGCGGTCGGATGGTTCCTGCGGGCCCCCGCGGAACCGTCCGCCCGGTGGTGGCTGGCCGGCGCCATCGGCCTCGCGATACTCCTCCGCTTTCCTGATGGCTGCTGGCTCGCCCTGCCGCTCCTGGCGACGGCCATCTGCGTGCGCACGTACCGGACCGCCGCTCCCGCAGTGATCGGAGGAGTCGCGTCCGGCAGCGTCCAATGGGTCGTGGAAGCGTATATACGCTTCGGCGGAGTCGGTGAACGGCTGCACCTGTCCAGCGCCACCGAAGGCGGCATGGGGCCCGGGAACGGTTTCGCCTCCGGCGTCGCAAGCGCCTTGCACAGCCTCAACGGGCCGCTTCTCTGCCGCCCTTGCGACGTCCCACTGCACGCCCCCGCGCTCGTCCTGTGGTGGCTGGCCCTCCCCTTGCTCACAGCAGCGGCGCTGGCGTCCACCGCGCGCCGACGCCACAGACTCGCCCTCACCGCCCTGCCGGTGGCCTGCTGCGCTTCCTGGCCTTCCCCTACCTCTTCCTCATCGACTATTCCGCGCCGCGCTTCTTCCTGCCCGCCTATGCCCCGCTGGCACCACCGATCGCCACACTGATCGCAGGCACACAACGCGACTCCGGCCAGCGCGCTGCCTCCTTCGCCCGCCTCCCAGGCCGCTCGGCCACCGCAACCGCCATCGGCTTGCTGTTTCTGGCCCACCTGGCGAGCCAGGTCGGCGTCCTCACCCAGACAACGGCCCAGGCAGCCGCCCTCTCTGGACGCTACCGACAGGCCGCCAGCACCCTGCGCCGGCTCGGAGTCCACCCGCCGTGTCTGGTCTCCGGCCCCCACTCACAACCTGTCGGCTACAACCTCGGCTGCGCCTCCGGCGACCTTCAGGGCAACAACCACTCGCTCACCCCGAACGAGCTGCGCCGACGAGCCGCCCGCGAACCCACCGCCGTCCTCACCACCAGCATCAGCGCTCCCCCGCCCGCACTGGCCCAGAACTGGCTTTCACACCCACTTCGCAATACGGGCGGATGGATCGCCTACGTCTCGCTTCCCGAGTAGCGCTTCAATGGCTGCGCCATTCTTGCCGGCCCTGCGGCAGGGTGGCGTTGTGAGATTCGGGGGCAGAATGGCTCCCGGGGCGGACTCCATTGCCGATGTGTTCGTCGCACTGTCGCAGGGAGACCAGCGGCGGTGGGGCGAGTGCTGCTTGCGAGAAACGACACTGAACGGTCGCCGCAGTGCATGGCACCTTTGCGACTGCGCCACCTGCGGGCCCGAGCTCGCCCAGGCGGCGCGAGCGGCTACATCACCGCGTCGGTCTGCAACGGGCCTGCGGTGAAGCGCAGTTCACGAACGCGCACCGGATCCTCGTCGGCGAGGTAGAAGATGTGCGTGAACGGGGCGCGCACCACGCGGTCCGGTTCGCTCTTCTTGGCCATGGTGGCCTCTCCCCGCAGAAGGCGGACACCGTCGCCCGCGGTCCAGAACTCCAGGACCTCGTGCGTGATGACCAGCGGCTCGTCGATCTTGACGAAGAACGCCTTGATGGCCTCGATACCGTGGATGTGCGCGGTGCCGAAGAACATGTCGGTGTCCTCCGTCAACGGCGCGAAACCCTCATCGAACTCCAGCGTGTCGATGGCGCCCATGAACTTCACGACCCACTCGGGCACCGCCGCTGCCTGCGCCGTGTTCGCCACCGCCATCATCCTCGCCCTCACCCTCATGTCTCGAACGAGCTGCCGTCCACCGTAACCCGACGGCCCCGCAGCCGGATCAGCGGATAGCGACCGGGCTGACGGGGGAACCGGCCCCGCCGGTGATGCGCAGCGCCGTGGCCGTGAGAAAGCAGTCGTCCCAGTGGCCGTCGGCGCGGCAGGCCTCGGCGAGGTCTCGAGCTGCCCCATCTCACCCAGCAGCATGCCGCCCCGGCTTGAGCATCGTGACCGTCCGGGTGATCGTGACGCCGCCCAGCCCCCCGTGCGCTGGGTGCCGCCGGCCTCCAGGCGGTCGACGACGAACAGCTCACGGCGGCGCCGGCACAGCGTGCGTTGGGCGGCGGCCACGATGCCGGGACGCTCGATCAGCAGGCAGGGGCCAAGCATCTCCATGGCGCCGGCCGGGACGCAGGCCGAGCGCGAGCGGCAGCCCTGCGCGCACTCCGCCGGTCGCTGCGTCATCGCAGACCACCCCGCCGCACCACAACGACCGGGGCAGGCCCTCCCGCCAGGTACCCGCATAGGCCGACACTCGTGCTCCAGCCTCGTCTGGGCCGCAAGGACAAGGATCACCACAGTGCCTCCGCAGCCGCGGCCTCCTGGGCAGCCACTGCATCCACCTCGGTCCGGTGATGGACTGGTGAGATGTCCGGGCTGGGTGCATGCGACCCACAGTGATGCCGTTTACGTGAGGTGGAGGGTGGCCAAAGCGGTGGTCCAGTCGGTGGCGATGGCCTGCTGGGCCTGGTCAAGGGTGATCTGCCCGGAGCACAGCGACTGGTGCAGCTTGTTCTCCACGGCGTCCTTGGGGTTGTTCGGGCCGCTGCCGGGCGTATGACCAGGAGACGGAGGCTCGACCCACAGGTTCCTGGCATCGTTGGGGTCGCCGCCGAGCTCCAGGGAGACGAGGTGGTCGTACTCGGCGTCGTGCAGGCCCGCGGTGTAGCCGTAGGAGCGGGCGTTCGCGGCCTTCTCGACGCTGGTGACGGACACCGGCGGCCGGATCTTCGAGGTGTAGCCGCCCGTACGGCACACGGTGGTCTTCAGCGTGGCCTGGGTGACGTCCGGGTTCAGCGCACCCGGAGTGCACGAAGCGTCCTGCAGGGGCTGGCCGTGGACGGTGCGGTAGTGACACATACCGGGAGCGGGCTGGGCCTGGACCGTATAGTGCGCCTGCGGGCCCGGCCCCTTCGCAATCAGCGACGCGGCGGCACCGCCGCTCCCGGAAGCGGCCGAGCGGACCGGCGCGGCGCCGGACGCCCCGGCGCTCTCACGGTGCTTGCCGCTGGCGGACCCACCGCCGTTGCCGCCGCTGCAGCCGGTGAGCAGCACAGTACCCAGCAGCACGGCCACCGTCGGCCGCAGCGCAGACGAAGACAGGAACATCGCGGCCTCCGGGAGTGCGGGGACATGACCAGACTGGCAGGCCCCAGCGGTACGGGAAGCCCCCGGGAGCGTGAAGTTTCGGTACCTGCTGTGACTGCGTGGCCTGCTTCCGTCCGTGCATGCTGCGGGGCCAGCGTCCTGGCCCCGCAGCGTGCCGCCGCGCGGGAGTACGGCCCCGGGTGTGCCGCAGCCCCCTCGGCTGCGGCACACCCGGGGCCGGTGCCGGCTCTGGCCTGTTAGCGGTGGTTCCAGTGCTTGGTGTCGACGATGAGGTGGTGGTCGTTGCGCAGGACGGCGGTGTCGCGGTGGTTGTCCCACGCGTAGGTGCGGCGGTCCTGGTAGACGTCGCGCATCGTGTCGTGGCCGCGGCCGGTGTGCACGCGGACCTGCTGGTGGCCTCCCAGGCGCAGGTGGAAGCGGTAGGTGGCGTGGGTGCGCCGGCTGGTCAGCGTCCAGCTGGTGAGGTTGACCGCGTGGCGGCCGGTGTTCTTCACCGTGACCCACTCGGCGTTCAGCGACCGGTTGGAACCGTCGTCCCGTCCGGGACTGTCGGCCTGAACCGCGCCCAGCACGACCGGAGAACGGTGGCCGACCGGCAGCTGGTGGCCGGCGGCCGACGCCGGACCCGCCAGGGCGGTGGCCAGGGCGGCCGATACCGCCACAGCAGCGGCCAGACGCGGTACGAAACGCATCACGTGATCCTCCAGAAGGCCGCCCCGACGTACGGGGCGGGTAGTACCCAAGTGCCGACCGATCGCCGGACGAAGACCACTGTGGAACCACCCGGACGCGGGTGGTTGCCGGTTTGACGGGCCATTACGCAACATGGACCTCTTCATTTCCCCCACGCTCCGCCGCCCCCAGGCGCACACGCCCGGGCGCACGCGCGCCGCCGCACACCGCCCCGGTCACGCCCCACCCCGCCGGAAGGGCCCCCGGCCAAGGCACCGACAGCACCTCCAGACCCGTAAGCCGCACGGGGCACATCTGCCGATCCGGGCAACGCCGGCGGATGCCGGGCCATCTTTGGTGATGCGGGTGGTCGGGCCCGTACGGAGCCTCGGGCAGGAGGCGGTGTGCCGCTGTACATGGCCTGGCGAGGCGCGCTGGGCGATACCGGACTGTGGTGGTCCCAGACCCGCAACGGGACCACCTGGACACCACAACAACAGGTGCTCGGCGCAACATCGATGGAACGCCCGGCCCTAGTACTCCAGTGGGACTTCACCATTCCTGCTGGTCAGACGCGGTCTTTCGAGCCTAAAGGCTGTCCCGTATGGGGTGGGGATTATCCGGTGAGGGCTGTGTTGTGGAGGCGGGCGATGCCCAGGATGGCCTGGTGAACGCCGCTGCCCTTGAGGCGGCAGTCCCGCAGGATCTTCCAGTTCTTCAGGCGGGACAGGGCGTGCTCGACGCGTGCGCGGGCCTTGCGGTGGACCTTGTTCTCGGCTTCCTGCTGCGGGCTCAGGGTTTCCTGCCCGCGTCGACGGCGGTGAGGAATGAGCAGGCCGGTGCCCTGATATCCGCCATCGGCGAGCACCGGAACGCCTCGACAGGCGATGTCGACACCCGACTCGGTGAAGGCCCGGCAGTCGTTACGGCTGCCGGGCAGGGGAGCGCCGACGGCCACGACCAGGCGGCTGTTGGCGTCGATGACGACCTGCAGGTTCGTCGAGTACCGGTAGTTCTTGCTGGAAGCGGCGACGCTGCGGTCCCGGGTGGGAATCAGGGTGCCGTCGACGATGTAGACGGTGTCCTCGCGCTTGCGGCGGGCCGGTGAGATCGCCAGCAGCGGCGCGAGGTGGTCCAGGATCCGGTCCGCGGCCGACTTGGAGATCCCGAACAGCGGCGCGACCTGCCGCAACGTGAGGTTCGTGCGCCAGTACGTGGCAACCAGTAACACCCGGTCCTCCAGCGGCAACCGCCACGGCCGGCCTCGCTGGACGTCACCGCCACGACGACGCACCAGCGCGACCAGGCGGTTGAACTGTGCCGGACTCAGCCCGGTGAACGGCTCGATCCACTTCGGATCGTCTGCTGACATCACCCCACCCATGCCCCGATCAACGTCCCAGCGGCCCCATCAGTTACGGGACAACTTTTAGCGGGCGGACGGTGCCCCGCGGGCCGGTTCCGGGATACCGCGTCAGTCGCGGACACGTCTGCGGTAGTGGCAGGCGCGGGCGATGGCCTGGTGGCGTCTGCGCCAACGGGACCAGGTCAGTGCGCCGCCACCGCGGTGCGCCGGCCAGGGGCGGACAGCAGCCAGCAGACGCCGGACCTCTGCCACGGTGAGCGGGGCCAGGCCGGCTGTGTCGTTTCGGCCGCCCCCTTTTTGACCGCGGCCGCGGCCATGGCGGCGAGAAAGGCGTGCGCGAGCATGGCCAGGGTGATGTGCCGATACCAGCCTGGGTAGCGGCGCACTTCGTACTGGTCCAGGCCGCACTGGCCCTTGGCGGCCTGGAAGCACTCCTCGATCGCCCAGCGGGAGCCGGCGACACCGACCAGCCTTTCAACGGCAGTGCCAACGGGCGCGTAGGCCAGGTAATAGGCGATCTCGTCGGGACGCCTGAGGCTGCGTCGGGCCAGCACCCACCGCTCGTGCGTGGGCGGATCAGGGTCGAAGACGAGGTTGGCGGGCAGCTTCGCCGCGGCCCAGTCGTAGACGCGCGGTCCCTTGGCACCGTCGCCGCAGGACAAGATCTGCCAGGCGTCGTCCGGCGCATCGGCAATGACCTGGTCGATGCGCCAGATCCCGAACAGCGACTTCAGCTGCTGGGACTTGGGCACCGCGAGCACGTAGCCGACCTGGGCCTGCTCGAGCAGGTGACGAAAGCGCCACTCCTGCCCGTAAAGACTGTCGGCGGTCACCCAGGCGATCGGCAGCGACGAGGCCAGCGCCCGCAGGACCAGGGTGTGGGCCAGTTCCCCCTTGGTAGCGAAGCCACGCTCGGCGGGGATGCGGGCGGCCCGGCAGCGGTCCCCATCGTTCATCCACGACTTGGGCAGATACAGCTCCCGGTCCACCAGCGCCCGCCCCCGGCTGGAGGCATAGGCGGCGAAGACGCCGATCTGGCAGTTTTCGGTCCGTCCGGCCGTGCCGGAGTACTGCCGCTGCACCCCGGCCGAGACGGTGCCCTTCTTCACGAACCCGGTGTCGTCGACGATCAGGACGCCGCCCGGGGCGCCGAGCTTCTCGGCGACGTAACTCTGCACGTCATCGCGGAGCTCGTCGGGGTCCCACCGGCTCCACGACAGCAGGTGCTGCAGGCCGTAGGGGCCGTTGTGACCGGCGTACTCGGCCAGCTGCCAGCTGTTCTTGCGGCTCACCGGGCCCAGCAGGCCCCGCACGTAATCCCGCATCCGACGCCGCACCTCGACCCGGCCGAACCTTCCGCTCACCCGCAAGAACAGGTCTTCGAGCTCGGCGCTCCAGCGTCCCGTGACAAAGTCCGCCATCATGCCCCGAGCCTGAGCGTTCCGCCCCGCTGTCCACGACGACATCCCGGAACCGGCCCGCGGGGCACCGTCCGCCCGCTAGGCTCGAAAGACCGCGTCTGACCAGCAGGAATGGTGAAGTCCCACTGGAGTACTAGCCGCCTGGCGCGGCCTGCTCCACCTGGCCTGGCGCGACGAACGCGACCAGGCACTGTGGTGGGCCGTGAGCGACGGATCCAGTTGGAGCCGACCGCGTGCGGTCCCCGGCGCCCACTCCAGCCACTCACCCGCCCTGGTCGCCGGCCACCACGGACTGCATCTGTACTGGAAAGGGCCGGGCGCCGACGAGCGGCTGTTCCACGCCGCCTTCGACGGCCGGTTCTGGATACCCGGGCAGGCGCTGTTCAACGGCTGGCCCATGACCTCCTCACGCCCCAGCGCCACCACCACCCACACCACCCGCACCTGGCTGTCCTTCACCGGCGCAGGCCGCGACCGCACGATTCGCCTGTGCCCCTCCCCCGACGGCACCGTATGGAACCCCCGCAACATCCTGCCCGGACCCCAGAGCGCGGCCGGCTCCTGGCCCTCGGTGGTCGGCCGGAGCGGGGCCGGGCGCGCCGACCGCCTGCTGCTGGCCTGGCCCGACCAAAACGGCGCCGTATGGTGCGCGCTCTCCCAGGACGCCGCCCAGCACTGGTCACAGCCGGCCCCCGTACCCGCCCGCACCCTGCGCGGCGTCGCCTTCGCCGGCTGGGACACGGTGGACGCCTACGCCGCCTGGGCCGTGGCACCGGACGGCGACTACAGCATCTTCTGGGCCGACACCACCGGCAGCACCGTCTGGCGCCATCCGCACACCGGCCATCTGCTGCAGCACGGCCAGGGACGGCTGGACGAACGCGCCTCGCTCAGAGAACCGGCCATGGCCGCCCACGGCCACATGTGGCGATGACCTCGCGACCGTCCCCCGGAGCTCGAACAGATGGAGCCGACCTGGGTGATGTCTCCCGCGTGGCGGGCGCGGCACCAACACTTCACTCCCGCGCTCCGCTGCCCGTTGAGTACGGTCTTCGGGTGGACAACGAGTGGGGGGACGGCGCCAGCACCCGTCCTTTCCCGCCGTCGCCGAGCGCGCAGCCCCTCGATATCTCCAAGCCCACGCCCGCTTACACGGGCTTTCCGGGGCACGGCAGGGTGCATGGCAAAGAGCCGGATGACGGCCGCGGTTGGTTCCGCCTGGTGCAGTCCTGGGTTACGAGGCCGGACAGAGTCCGTCGGCGCAGGGCGCCCGGCCCGGCGCGGCGTCAGTTACACAAAACGATGCTTGCGCAACTGCAGCAATGGACCATGCTGGTTGAGCTGGCGGCGGCACCCGGGTTGTCGCCGAGGCAGCCGGAACCGCGCACAGGCAGGGATTGGAGATCGAGGAGCGCCATCGCGGCCTCCTTGGTGCGGAAGGGCAAGTACGGGGCGAGGCACACAGCACCGCCGGGGCCACTGAAGCGGCCACTGCTCCTGGTAGCGGACAGTGTAAAAAACGATCGCCCCCCAGGATACGGCGATACCGGCCAATCACCGGCCCGCAACCCTCCTGAAAAACCTCGCCGGGCTCCGCCCGGTTCTGCAAGTCCCCATCGGTCCGGCGGTAAGCCGGGTGCTGGCCTGTTTCACCGCACCACCTCATCCTCCGAAATGCTCACGCCCATCGTCTCCTCTCGCTCAGGGCTGCGTCCGTCTGTGCGCGCGGGTTCCGCGGCGGTCGCCGACCACGCCAACCTGCGGGCCGCACTCGATTGCCGCCTCGCCGAACGGAACGGGCTCAGCGTGCTGGAGCTGGCCGGGGCCCTGTGATTCCTTTGAGCCTGTGTCTCTTCCCTGATGTGGATCTGTAGGGCGGTCGCGAAGACGTCGCAGCCACAGGGGTAGAGCGGCGACGAATGGGTATGTCCCCGGCACGGAGCGCGCGTTGTGCCGTTGGGGTCACGACGCTCCCGGAGGTTCGAGGCGTTCGACTCGGCGTATGGAAGGTTAGATCTCGTTGCCCCGACCCGCCCAGTACCACCTCCTGCCGCTTCCCGACGGATCGTGGGAGACGGTCAGCCTCATAGCTGCTGCCATCCGCTGCCGCGCCACCGTGCCGACCGTGATCGTCGATGTGTCGGCAGTAAACCGGATGACCATCGACGCCCTGGCGATCCTGGTCCGCAAGGCCATGCGGCTGCGCTCGGTCGGCGGCGAACTCCTGCTCGCCGGCCCCTGCCCGGCCGTCCGCAAACTGATCGAACGGACTGGAACCGCCCCGCTCCTACGGGCCGTTGCAGGCCGTGCCGCCGCGGTGCGCGCCCTGGCCCAAGACGGCCGCACCTGGCATCAGGTAGACCTGGGCGCCGAGCCCAGCACGCTCTTCCCTGACCTGCCGGAACACCTGGAGCCTTACCCCCGGACCTGGTGACAGGCACGTGAGGCAGCCGGGGGTGCGTGGCTCCACAGCTCACAGCAAGCATCGTTCGACACACCGGTCATGACACCCAATCGAACGGCACCCTCACTATGGTTTTCCAAGGGTTATGACCAGCGGTCCGGTGCGGTATGTGCCCGTGCTACGACAGCAGCCCCCCGAGGCGTCGCCGTCTCAGCCGCTGGGCGGATGTCGCCGGGCAGGGGTCACCGGCCGACTGCGATGCGCCACTGCGGGGCACGCTGTTCCTCGGGGCAGGCCCGGCGTCCGGCTTCGGTGGGGTTTGTTTGGCTTTGGCCACGGCAGCGCCCAGATGCCCGCGGACGTTCTCCGACAGGAGGGGACCGTGAACGCTGTTGACCAGGTCCTCGGCCAGGCGGTGCAGTTTGGTGTTGGTGTTCTGGGACGTGTTGACCAGGGCTGCCCAGGCGGCTTCGGGGGTGAGACTGAAGGTGGCCATCAGAATGCCGCGGGCCAGGTCGATGGCCGGGCGAGTCTGCATGGCACGGCGTAGATGCGTGACCTCCTCGGACCAGTCCTCGGCGGCTCGTAGGTGCGAGGTGTTCGGCCCGTGGATGGCAGGGCCGGTGGCCTGCCGGAGTTCGCAGGCCGGTGCGGTGACCAGTTTGCGGGCGTCGGTCACCTCCAGCAGCCGCTCGACGGCGGGACTGCTGGAGGCGATGGTGACGGTCTTGTTGTGCACCAGGGCGCGCAAACGCGGGCGCAACAGCATGTTGAGCCCGGCGAAGTCGCAGAACGGCACCGCGAGATGAAGGTCGAGATGGCGGACTGTGCGCCGCAGGACGTCGCGCAGTGCGCGCTCGACCAACGGGCTGGAGGGTAAGCCGAGTTCTCCGCGTAGCGCCTCGCCTGTGCGCTCGTCGGCGCACAAGACGCGCACCTCATGGGCCGGGCAGTGCCTACGAGATCGCCACCGGCAAGGTGCTGCGCCACCCGGCCGAAGCTGGGATGGGCCTGACCGTGGCCTCCCTGCTGACCCTGCTCGTCCAGGATGAGGCGGAGCGCACCGCGCAGCCCAACGACCCCTCGCACCACAGCACGGCCTGACGCCACCGGACGCACACCGCACGCCACCCGCGACCGGCACGAGGGCCACTGCCAGCGAGCCGTCAAGGTGCCCCATCATCACGATGCGCCCTTCACCGCCGGCGGGTTCCCGGGAGCGCGGACAGGCGGCGCCGTGCCGTTTCGGCGAACTCGACAGTCAGGGACACGGGAAGACCCTGCCGCAGCGCCTGACCGTCGCCCGCGGTCGCCGGTGAACGGTAGCGCACGGCCCGAGCGGTGATCGAGAACAGCCGTCGGTTCATCGACGCGTGCTCCCAAATCGCCTGCCCCCAGCGCCCGCAGCAGTCTCGAACGCCAACGGGCACCACAGTGCCGACGCCCTCCCGACCGCCCAGGGCACAGTGTTCCAGAAACTGTGTAGCCGTCCGCGTGGCTGCTCTGGCACCGCCGATTTCCCGGGCCGTCGCAGGGCGAAGTCGACTGCACCCGTCCGGCGGAGTCTGCTGCCCACCCAGGCGGGCAGGCGCCCCGCGCACGGGTCGGCTCACTGCCGCACTGACGCTCGGGGACAGCGCACCGTGTCACCGTCCGGTGGGACGGGCGCCCGCACACCGCCCGCCCCACCGGGCCGGTCGGAGCCAGTTTCGATGAAGCGGCCGAGTCCACCTGCGGCGCGGCCATAACACGGGAGCGGCGTGATGGGGCGCTGGCGGACGTTCGGCGCGGTGCCACGCCCGTACGGGAGGCCACACCCCCGGGGGGACAGACTTCCCGGCCTGGTCGAATCCCGCAGCTCAACAGCCTGGGGCGGGCTGGCGTGGCGGGGGCGTGTGATCGTCGGGCGCACGCGGGGGCGTGCACTGCCAGCGCGCCGCGGTTGTGCAAATGTCCGTGTTCTGTAATGAGCAGTCCGATTTTCAACCACGGGGGCGAGGGCGGGCGCACAGTGAAGTCCGCCCGGCACAAGACCGGGCATCGGCTCCCACCGGCCCCGCCCGCGGCGGGGCTGTCCGCAGGAGGTTCGTCATGATCCGCTCCGCTCGTCTGGCCGCCGTCGCGCTCGGCGCGGCCGCCGTGGTCACCGCCGCCGCGCTGCCCGCCTCCGCCACCGGCGCCCACACCCCGCCGGCCGCGTACCGCTCCCCCGTCTTGATCGGCGCGGTACAGGCCGACTCCCCCGGCCGTGACGACGGCTCCAACCGGTCGCTGAACGCCGAGTGGGTCACCGTGAAGAACACCAGCCGCCGCGCGGTCAACCTCGACAACTGGACGCTCACCAGCGAGCGCACCCACAAGACCTACCGCTTCCACCACCTGCGCCTGGCCGGCCACCAGGAGGTGCGGGTGCACACCGGCCACGGACGTGACACCTGGCGCGACGTCTTCCAAAACCGCCGCGACTACGTCTGGGACAACCACCGCGACACCGCCACCCTGCGCAACGACCACCACCGCGTCGTCGACACCAAGCACTGGGGCCGCCGCTGACCTGACCGGGCCGGCTCCCAGCGGCCCCGTCAGCAGGTGCGCCGCTGCCGGACGGGAGCAGCGGCGCACCACACCGCCTGGAAACACATGTTCATGTACCACGGATGGCGGCCGGCCTTGGCCCCGCTGCCTGACAGCAGGAAAATGGCGCTGGCCCGTTCCGAGCACTGTGCGAACGCAGTGCGGCCCGGGCAACGAGCAATGATTCCGACCATGGCGACACACGGCTGTCCGCCCGAACAGCACCGCGTCCAACTTCAGGACGGTGTCATGGTCACCGAGGAATGCGCCCTGTGCGGCTACCGCATCACTTACGGACCGGTCGGACACGATCGCGCATACCCGCCTGCCCGGCCCCCGCTGGCAGGTCCGCGCCGCAACGGCGGTCTGATCGCGGCCGTGCTCGTCGCCGCCCTGGTGGCCGGCGGCATCGGCGGCGGCATCGGCTTCTGGGCCGCCAACCGCAACGACACGAACTCCACGACGGTCTCCGCCTCCGGCGACCCCGAGGCGCTCAACCGCAAGCCCACCTCCGTCTCCGGGATAGCGCAGAAGGCGCTGCCCAGCGTCGTGACCATCGAGGCGCAGGGCGCGACCGGCGAGGGCGGCACCGGCACCGGCTTCGTCTACGACAAGCAGGGCCACATCCTCACCAACAACCACGTCGTCGCGAGCGCCGCCCAGGGCGGCCGGCTGACCGCCACGTTCTCCAACGGCAAGAAGTACGACGCCGAGGTCATCGGCCGGGCCCAGGGCTACGACGTCGCCGTCATCAAGCTGAAGAACCCCTCCGACGCCAACCTGGTGCCGCTCCCGCTCGGCAAGTCCGCGAACGTCCAGGTGGGTGACGCGACGATCGCCATCGGCGCGCCCTTCGGCCTGTCCGGCACGGTCACCACCGGCATCATCAGCGCCAAGAACCGCCCGGTGGCCTCCAGCGACGGCGGCGGTGCGACCCCCTCGTACATGAGCGCCCTCCAGACGGACGCCTCCATCAACCCGGGCAACTCCGGCGGCCCCCTGATGGACGCCACCGGCAGCGTCATCGGGATCAACTCCGCCATCCAGTCCGCGGGCAACGGCGGCGGCGGTTTCGGCGGCGAGAGCCAGTCCGGCAGCATCGGCCTGGGCTTCGCCATCCCGATCGACCAGGCCAAGCGGGTCGCGGGCGACCTGATCAAGAAGGGCCAGCCGGTCTACCCGCAGATCGGCGCCCAGGTCCTGATGCGCGACACCGGCGACGGCGCGACCACCGCCCAGAACGGCGGCGCCGACGGCTCCGCCTCGGTCACCCCGAAGGGCCCCGCCGACCAGGCCGGCCTGAAGCCCGGCGACACGATCACCAAGCTGGACAACACCATCATCGACAGCGGCCCCACCCTGATCAGCACCATCTACCAGCACAAGCCGGGCGACAAGGTGACCCTCACCTACAAGCGCGACGGCAAGGAGCACACCGCCCAGGTAACCCTGGGCCAACGCACGGGCGACAAGTGACGCGCTCGCGCCACACCAGCCGCGCTCCGGCGGCGCGCAGCAGGTTCTTCTCGCGGCCGTCGTAGCTCTTCATCGCCCAGGGGACGTTGAAGGCGTACTGGACGAGCCTGTGGTGACAGTACGGCACGCGCACTTCCAGGCCCTGGGCCATACTCAACCGGCCTTTGGGTGCAGGAGTTGGCGCAGCCAGCGGGTGAGAAACATGTGCTGCATCTCGCGCTGCCGGTGCCCGACAGGAACCTCGTCGTCCAGGTGCGATACGGCAGCCAGCGCGCTGCGGTAGGTGTCGCCGCGAAACTCGTCGACGTGGCAGGCCGAGTCCGTGGTCGAGCGGCATGGCGGCCTCGTCACCGGTGGCCAGCAGCCAGGGCAATGCCATAGCGGCGAGTGCCTTGGCACTGGGACCAGGGGTAGCCGCCGAAGACCTCGTCGGCGGCCTCGCCGGACAAGGCGACGGTGGAATGCCGCCGTATCTCTCCGAAGAGGAGGTAGAGCCAGGTGTCCATGTCGCCGACGCCGATCGGTGAGTCCCTTGCCACGACGACCGCTTTGCGGCACTCGGGTCGAGAACGACCGTCGAGTGGTCGGTGGCGATGAAGGCGCCAGCCCCGGTGGCCTACGGGGTGTCGTGGCCGGCGCGCAGCACGTCGCTGGTGAACTTCCCGGTCTGGTCGCTGTCGTCGACGGTGTACGAGCGGATGCGAGCGTCCGGGCCCCCGTGCAGACGGATTTCGCCGGCGAGCAGAGCAGCCCGGACGGTGGAGTCGATGCCGCCGGACAGCAGGCTGCACAGCGGTACGGAGAGGATCCTTGTCCGCCGCTCGGGTGGGGGCCGGGCTTTGGCGCGCGAGGTTGTCGCCGCTCAGTTCTGTCGTCACGCGATCACCGCCACGGCTGTGCCGTCATCAAGGTTTCGGGCAGCCGGTCCTCCACGGCGGCTGCAGCTTCCTCGGGTGCGGCGGCGGGCGGACACCTGCTCCGGGTGCGCCAGGGAACTCCGTCCGGGTGTTACTGCTGCTCAGCGCGGCGGCGCAGGATCGCGTCGTACACGTCTTCGTCGAGGTAGCCGTGGACCAGTGCGTCGTGCACCTCGTCGAAGGCGCCCGGTGCCGGCAGCGCGGCTCCGTGGTCGGGCAGTCCCACAGGAAGCGTGTCTGGCGGGGCGAAGGGCGGCCAGGTGGCCAGCGCCTCGACGAGGGTGTCCCGGTCGATCTCGCCGGCGGCGTGACGCATGGCGATGTGCAGCGGGCTGCGGCCGGCGCGCCCTTCCACGAGAGGCGGAAGCGCCCGGGCCTTGGCGACCAGGGCGCCGACGGCGACATGGGAGATACCCAGCTTCGCGCCGATGGCGCGGTGAGAGGCACCGGCGTCGGCCGCGGCCAGGGCCGCCAAGGCGGTGCGTTCGTGGGCGAGCGCGGCGCGGGCCTTGTTGGCGATGCGCACCGCCAGTTCGGTGTCGCGGGCCCGGCCGACCGTTTCAAGGGCCTGCTGAGGGGCCGGATTCATGACACTACCTCCTTGGTAACCTTTACTTACCGGAGCTGGTAAGTAAAGGTTACCGGAAGGGGGCGGGACTCGAAGGCGCCTACTGCCTCCCTCTCTGCGGCGCGACCGCGCAATGGTCGCGTTGCAGCGAAACACCTGGCGGGCTCGGCGCGGCCGTCGACGTCCCGTCCGCGGCCGAAGGCGCGTCGGCCCCGGCGGCCCCTGTACGGCATTTTTCGCTCCGCCGGTGACCTCGTCGGTGTTCACACACTGCGGACCTCTTCCGGGACAACGGGGCGGGGTGTAGAACTCGCAGGGCTCACCCGGCGCATCGAACAGGTCGGGCGCCGGCCCCTACGACGGGAGACCGATCCCCCATGTTCCATCTGATACGGCGCAGAGTGCGGACGGCCGCGCTCACGGTCTCGGCCATCGCGGCCCTCACCTTCGGCGCGACCGCCCCGACCGGCGCGGCAGCGGCCCCCGCCCCCGCTCCCGGGAAGCAGGGGCCGACCTCGGTGGCCTACGTCGAGGTGAACGACCACAGCATGCTCAACGTGGGCAAGTACACCCTCGCCAACGGCGGCGGCAACGTCTTCGACGTCGCCGTGATCTTCGCAGCGAACATCAACTACAACACGGACACGAAGACGGCGTACCTGCACTTCAACGAGAACGTGCAGCGCGTCCTTGACAACGTTGCCACCGAGGTTCGGCCGTTGCAGCGGAAAGGCCTCAAGGTCACCCTCTCGGTGCTCGGCAACCACCAGGGCGCGGGCTTCGCCAACTTCCCGTCGCAGCAGGCGGCTTCGGCGTTCGCGAAACAGCTGTCGGACACCGTGGCCAAGTACGGCCTGGACGGCATCGACTTCGACGACGAGTACGCCAAGTACGGCACCAACGGCACCGGACGGCCCAACAGCAGCTCGTTCGTGCACCTGGTGACGGCGCTGCGCGCCAACATGCCGGACAAGATCATCAGCCTCTACAACATCGGCCCGTCCGCATCGCGCCTCTCCTACGGCGGCGTCAACATCTCCTCCAAGTTCGACTACGCCTGGAACCCGTACTACGGCACCTGGCGCGTCCCCGGCATCGCCCTGCCCAAGACGAAGCTTTCCCCGGCGGCCGTCGCGATCGGCAGCACCTCGCAGAGCACAGCCGCCAGCCTCGCCCGCCGCACCGTCCGCGAAGGATACGGCGTATACCTCACCTACAACCTCGACGGCACCGACCGCAGCACCGATGTCTCCGCGTTCACCAGGGAGCTGTATGGCAGTGACGCCGTATACACGCCATAAGACGCCCACACGCCTCGGCACGCGGCGCCCCTCTGGCCCTCACCGCATCCAGTAGAAATATGCCCCGCACAGGCCGCGCCTCTGACAACGATGTCGGGGGCGCGACCACACACGGTGCGCCATCGGCGGCCCTCCGACGCCCCCCCGATGCGCTGGCTCGTCAGTCCCTGCTCACAGGACGGCAAAGGCGGAATACCGTTTCGTACCGAGACGGGACAAAACGCTTAGTAGCAGGCACATGTCGCTGAAGCCCAGCGCCCACGGCCGTGCTTCCAGCCGACCCTCAGCTCAAGATGAGTCGGATGGCGGCCATTTCGTCGGCCATGGCCGGGTTCAGCTTACCGTTTTCGTCGAGCGCACTGCCGCTCGGGCGCCCTGCCGCCGGGAAGAGCGCGCCGGTGCGTCAGCCGGCGGTGGCTGACGGCCAGGGGGAGTGGGTGTCCGGTTCGTACACCGAGACATGCCGCAGGCTGGAGGCGGTGTACGGCGTGCCCCGCCAGTCTTCCGAGCGGTCGACCAGGCGCAGGCCGGACAGCTGGGCCAGCAGGTCGATCTCGAAGGGGAAGGCGTAGCGCAGTACGTGTTTCCGGGTCTCCGGGGCGCCGCCGCCGTCGACGATGGTGTGGGTCGAGAGCATGAGTTGCTGGGAGCGGTCCACGGTCAGGGTGTCCAGCATGACGGCCCGCTCGTCCAGGTGCCGCATAGAGAAGTCGGGTTTCTGCAGGTGGTGGTACGGCGCCGGGTCGAACGCTTCCAGAATGAAACGGCCGCCGGGGACGAGCTGTTCGTGGGCCAGGCGGAGGCAGCCGAGCTGCTGCTCCTTCGTGATGGCCACGAAGAAGGTGTTGAGGACGAGGGTCACGGTGTCGAAGACCTGGCCGGTGCCCTCTTCGGTGAAGTCGCCGAGCTGCGCGGTCACCGTCTCCTGCGGATCACGTCTGCGCAGCTCGGCAAGCATGGCCTCGGAGCCGTCGAGGCCGTGTACAGTCAGGCCCCGCCTGGCGAGCGGGACGGCGATCCGTCCTGTACCGACGCCGAGTTCGAGGACGCGGCCGCCCGGCGGGGTGTGCGCGGCGATGAACTCGACCGCCTGGTCCGTGTCCTCGCCGATCGGGTACATCCGGTCGTAGACGTTCGCCAGCTTCTGGTCGTAGATCGCGTTGCCGAGGGTCATGGTGCTGGTCTCCGAGGGGTGGGGTGGTGGCGGTGAGGGGGGTGTGCTGTCGGCCCGGATCCGCCCCGTGCCGCCCCAGGCTCCCCCGATCGCTCAGCGGGTCCCGGCGGGGTGGCCAGTGGGCGTCTCCGGGCGGCCGCGGCGCGGTGGGCGACCACGGCGGCCTGCACCCGGTTAGTCAGGCCCAGCTTTGTCAGGATCGTGCTGACGTGCTCCTTGGCGGTGGACGCGCTGAGCAGCAGGTGGCGTCCGATCTCCGCGTTGGTCAGTCCTTCGGCGAGCAGTTCGAGGACCTGGTGCTCGCGCTCGGTGAGTGTGCCCAGGCGCGGGTCCGGTTCGTCGTGACGCATGCCGGTGTCGAGGTAACCGTCGATGACGATCCGGGCCGCCGCAGCGGACAGTACGGTATCGCCGGCGGCCAGCACCCGGACCACGTGGGCCAGTTCTTGTGGTGTGGCGTCCTTCATCAGGAAGCCGGCCGCGCCGGAGCGCAGCGCCGCGGCGATGTCCTCGTCGGTCAGGAACGTCGTGAGGATGGCGACTGTGGGTGGAGCCGGGCGCGAGCGGATCCATTCGAGAGCGGTGAGCCCGTCGACGTCCGGCATCCTGAGGTCCAGCAGGACCACGTCGGGCCTGTGGGTGTCCACCGCTTCGAGTACGTCCCGCCCGTCGCAGACCACCGGTACTTCGATGTCCGGCTCGCACTCCAAAATACGCTGCATACACGTCCGCAGCAGAATTTCGTCATCGACGATCATCACGCGAATCATTACGCCCTCGTGTGCATGACCCCTCGGCCATATCACGTTTAAGAGGGTGTCCTATGTGGTGAGCTGGGCATGGCGCTTGTGGCAGACGATGGCGGCGGCGAGGCCGAGAAAGGCCAGGTAGTTGTCGTGGTGGCGCTCGTATCGCGGGTTGAGCCGGCGGTAGCCGGACAGCCAGGCCAACGTTCGTTCAATTACCCACCGGTGACGGCCCAGGCGGTCGCTGGGTTCGACGCCGATGCGGGCGATACGGACCGCGATGCGCCGTCCGCGCAGCCATCGCCTCAGGTGCGGCCGGTCGTATGCCTTGTCGGCATGCACCTTGCCCACCGGGTAGTTCCGCCCGCGTTCGGGGTCGTGTTTCGTTTGGTAGCCGCCGATCATCGGCTTGAGGCCGTCGCTGTCGGCGGTGTTGCCGCCCGAGAGGCCGACCACGAGGGGCAGTCCCGCCGCATCGGACAGGATGTGCATCTTGGAACCGGGCCTGCCCCGGTCCACGGGGCTCGGACCTGTAAGTTCGCCCCCCTTTTCGCCCGCACGTGGGCGGTGTCCAGCACCAGGCGGGTCAGATCGAGAAGGCCGCGGCCAGCGAGCCGGTCGAGGACCCGCTGATGCAGGCGGCCCCACACCCCGGCCCTGGACCAGATCAGGAAACGACGGTGGGCGGTGGACTTCGAGATGCCGAAGCACGGCGGCAGGGCCCGCCAGGCGCACCCGGAGACCAGCACGTACACGATCGCGGCGAACACCGCCTCATCGTCGGTGTTCGCAGTTCCGCCGCCCTGAGGTCGCAGACGTGGCGGCGGCAGCAGCGGCCGGGTGATCTCCCATAACCCGTCCGGGACGATCCACCCCCAACGGTTGCTCGCCATACGAGAAACCTGCCCAGCTCACCACGTAGGACACCCTCTTAGCTCCAAATTCCAACCAAATGCCGGGGCACCAGTCCAGAGCCACCCAGTACTCTCACAACCATTGCTCCATCACAGAGCAGCAGGAGCGGCTGTCCACGCTGGGCATCAAGCCGCTCGAGGAGCCGTCTCCCGCACCGGCGGCCAGGCGGGCGGCGGGAAGGGCCCAGGCAAGGCGCGGCATGCCTTCCAGCGGAGCCTGACAGCCCTCGCCCAGTGGGTGGCCGGGAGGGCGCCGACCGGCCGGTGCCGCGCAGACACGCCGAGGAGATCACGGTCGACAGCGCAACCGATCCGGTGGTCGTGAAGCTGGGCTTATGGGCATCGAATGGGCAGCAGCCTGAGCTGGGATGCGCAGCGGGGCCGTACCGACTGCGGTCGATACGGCCCGGGAGGGTGAGACGGCTGGTCTTACGCGGCCATGTCCTCGCCGCTGACGAACGGCGGTGCGGAAGCGGGTCGGGGCCGCCGCCTTCCCATCCTGCTGCTGGCTCCTTTTGATTCGGGCGAGCAGTTCCTGGTGCGCCCTGGCCCACTTGTTGTCCCCGTGCCGAGGTGGACGTGAGCCCACCGCTACGGCGAGACACGATTCGAGGCCGACGAAGCGGATCACGTAGCAGGCATTGAGGAAGGCGATGGTCTGCTCGGGGTCGAGCCGATAACACCTGGCCCACTTGGGTTGCGCGTCACATGCCCGCCCGGTCGCGGAGAACACCTCCTGCCTGCCTCACAAGCTGCCAAGCGAGGCGTCATCGCTGCACCGAGCAGGCTTCGAGCCACAGCTGTTTCGCGAGTCGCTATCAGTTCGGTTTCGGCGACCACACCACAGCCCAGTGATCGCTAGCCCCAGACCTGGCGACTTCGACATGGCCCCGCCGCCAGTCCGAGTCGACATTGGAGACCATATAGTCCAGTTCTCCGCCACTCAGCTGAGTTGGATCATTCGGGCGGTAGATGTGCGCTGCAGACGGCAGCTTTTTGTCCTTCGCGAGGTCATCGGGCGCGCGGTTGAAGTCGGCCAGCACCGCCCAGTTGGGTATGTTGAGAACCTTTGCCTCATTGGCCGTGTTCCGCACTAGTGCAGCTGCATCCCCGCCGCCGCTAGCGCTGGCGTGCGCGGAGCAGAACAGTGTGGAAGTGTTCGTGTCGTTGACGCACAACAGTGGCCGGTATGGCCCGGTAATCGTCTTGATGTTGGCGGTACCGGGCTGCCATTTGGTCACGAGCCCCAAATTCTTCGAAGGCTCCCTCAATACATACAGGTAGCGGATGTTCGGACGACTGGTCGACCCAATATTCCACTCATACTCTTCCAGGCGGCCGCCAGTTTGTACCGCTTTGGCGCCGGCGGGGGGGTTCTTCGGAACTTCTTGAAGTGCGACCACGTCCGTTTTGTGTTCATTGACCAGCTTGCCGACGTCGGCCCAGTTTCCGGCCTTGGATTGAATATTCCACGTCGCCAAGCCGGGTTCGGGAGTTACGGCCTGCGCTGGCGAGGGCACCACAGCCACCAGGGTGGATGCCACCAGCACTGCCATGATGACGTGACGTCCGCTTCGGGCTCCGTGGGTGACGCTACGACTCATCGCCAAATCCTCTCTTGCCAAATTTTTCAGGATCAGCCGCCGTGCTCGCTCAGCATTGCCCTGCCAGAAGCGGGTAAGGTCCATCACGCTAAGCCGGGAGCTGCGGCCTGGTCTTATCGCCCGGGGGCGGGGTGCCGGGCCGGGCTGCTTGGGCGGACCAGCCGTCTTAGCCATCGCGATATGGCCGCCCTTCCGACTGGAGACGCCCAACACCTGGGACTGGCCTGCTCGTTGCTGTGCAGGCAATCGGACTTTAACAGCAATTCCTGCCAGAGGACGATGAACAGGCGCGTGCAGGCACGTTTCCTTGCGGTACCTGCACGGCGGGAGCGTGGCCGAAATTTCGGGGAGGGTAACGAGCTCTTGCACGGCAGGTGGCGAGAGGCCGAACCCGTGATCGTTCATCATGCATGCATAGTGGGGAACGCGCCTCGAGCAGTGATGGTCAGCAACCGGAGGATCACGGGCCTGCCGTCCGAAGCGATTGCGCAACTCGTCGCTGAGGTAGCTGCTTAAGACGGTGTCCTACATGGTGAGGTTGAGGAGCCGTTTGTAGCAGCAGAGGGCGGCGGCGAGGCCGAGGAAGGGCAGGTAGTTGCGTGCATGGCGTTCGTAGCGGGGACTGAGCCGGCGGTAGCCGGTCAGCCACGACATCGTCCTCTCGATCACCCACCTGCGACGCCCCAGGCATTCGCTGGAGTCGATGCCCTTGCGGGCGATGCGGACACCGATGCGATGGCCCACAGCCATCGCCGCAGGTGGGGGATGTCGTATGCCTTATCCGCGTGCAGACGCCGAGGCTTTGACTGGTCTGCGCGGGATTCGTGTCCCTTGTGGAAATAGGACAGCATCGGCTTCAGCGCGAGGCTGTCGTGGGTCCGGCCGCGGAGATTCCGACCCGTAGGGGCAGTCCTGCCGCATCGGACAGGATGTGCATCTTGGAACCGGGTTTACCCCGGTCCACGGGTGACGGACCTGCAAGTTCGCCCGCTTATCTGTTTGAGGGGCAGGGTCAAGCGGTGTGTGGGCATGTGCGCGGACGTCTCGAGTGGCGTCCGGCGACATGATGATCGATGGGGTCGGGCTCACGGATGCGGCCGCTCAGTCTTTTGAGGCCCTCGGGCGGAGTGGAGCCGCTGGGCAGGGTGCCTGCAGGAGCTGGCCGCTGGCATCGTTAAAGGGATCGGGCGGGGCCCCGCACCGGGTGCCGGAGTTCGTCACACCGCGGCGAGCGCCTCGCCGCCGAGGGCCCGCAGGGCATGATGGGCCCGGCGGACGAGTTTGCGGGCCACCGACAGCGCGGCCCGGTTGCCACCGCACCTGGCTTTGACCTGCTGGTAGTAGGCGTAGTCGGGGGCACTGGGCCGGGCGGCGCACTTGGCGGCTTCGAACAGCGCCCATCGCAGCAGCGGCGGTCCCTGGCGGGCCAGGCGGTCGGGGCTGCGTTTGGTGTCGGACGAATAGACGGTCACGTCCAGTCCCGTGTGGCGGACGGCCTGGCGGGAGGAGGAGAAGCGGCGCGCGTTGCCGAGCTCGGCCCAGATGGCCACCGCGGTGACCGGCCCGACGCCGTAGTGCTCCAGCAGGGTTGCGCATCCGGGCTGCTTGCGTGCGAAGGCGGTCAGCCGGCGGCGGAGCGGGGCCATTTCGTTTTCCAGGGCATTGAGCGTCCGCAGCGCGGCCAGGACGGCTTGGTGGGCGGCGGGTGACAGTCCGTCGCCGCTGGCCAGCCGGGCCCGGTGGTCGGCTGCGAGGAGGTCCCCGGTGGGCGCGGCGACGCCGTGGTGGAAGAGCGTGGCGTGGATGCGCTGGACCCAGGCGGTGTGCTCGTCGCGCAGGTCCTTGTAGAGCCGCAGGAGGGTGCGCATCTTTAGGACCTGCCGGGGCGGAATCCAGGACGGGGGAAGACGCCCGTCGGCGAGCAGTTCGCGGATCTTGCGGGCATCCGCCCGGTCGGTCTTGGCCCGGCGCTTGGGCCGTCGGCCGCCGCGGTATCGGCCGGCTCGGCCAACTGCACCTCGATGCCGGCCGCCTGGCATTCCTCGACGATGAACCGCCAGCCGGTGCAGCCCTCGACCGCCAGTGCCGCCGGCCGCGGCAACTGCTCCAGCCAGGAACGGAACCGTGCCCGCGTCGCGGGCACGATCCGCCCCCGGCGGACCTGCTCAGTGGCGCCGTCGAGACAGTCGAAGGTGATCTGCCTGCGATGAACGTCCAACCCGCCTACGATGGCCATAACGGGGCCTCCTCACGCTCCCGAAGACAGTGGCTCACCAAGCATCGTGCTCCGCACCGGAGCGTCAGCCCATGAGCTGAGGAGGCCCCTCCCGCATGTCATCTTTTCCGGCTGGCGGGGAAGGGAGGCCAGGAGGATGTCGTAGTGACATGCCCGGGCGATGGCCGTGTCCCGCTGCTGCTGCCAGCGCACCCGGTGGGCGTCGAGGCCGGCCAGGACGTCCCGCCACGGCGCCCCGGGGCCCGCGCACGGACCGCCGACTGCGATTCTTCGGCATGGCTCCGGCGGGGCCACAGCAGGGCCTGCGCCAGGCTGGCGATCGTCAGCAGGTCGGGCCACAGCCGGCAGCCCGGCCCCGAGCACGTGAGCGACGGTCAGCCAGGACCCGCCCCCGAGTCCGGCAGGGCGTTGTCGCGTGGGGGCACCGGGTCCTGGACTCCCCACGTGGCTCAGCATCCTCCGACGTCGTTCACCACTTCACTGCGGACGGAACCGTGCCCCGTCACCGCGGGCGTGCCCGGTCATCGCCTGCACCAGGGTGCGGATTCGCTCGGGGTGGTCCAGCAGGAGCGGCACGATTGTCTCCATGGCCAGGCTGGGGAGGACGTCCAGGTAGAGCTCGTAGTCGTCGCCGCGGTCGGCGGCCAGGGCCAGCAGCCGACGGGCGGCGGTGTCTCCGTCCTGTGCGGCTGCCAGGAGCTGTCAGGCTCGTGCGACGGGCAGATCGATCTGCGGTGCGGTCTCCTGCTCGACCACGTCGATGAGGTTGGCGGTCTTTCGCGGGCGCTGGTGCGGTCCGCGGTGTCGCGGGCGCGCTGGCGGAGGAGGGCCGCGCGGCGGCCGGGACGAGGTGGTGTCACCGATCCGGCGGCCGGGCCCGGACCGCTCACCAGACCTGCGAGGGGCCCGCCTGATCTGCGAGGGACCCGTCATTCGCGAGGAGGCGGCAGCAAACTGCACATCCTGGGCGTACCCCACCGGCTGTTCCCGTCCATCCGTACGGCCGGTTTGCGCACCGTCCGGCTCGCGGCCGGCGCGCTACCGGAGCAGCTTTCATGGACCTCGTCGGACCGCCCGGTGTAGTTCGGTGGCCAGTTGCCGCCAGGTTGCGGAGCAGTCCTGGGCGAGCTGGGCCATGGAGAGCAGCTGGTGGGCAGGCGTGGAGTCGGCGAACTGCTGCAGCTCCTTGGCGTCGAGAGTGAGGATGCCGAGCCATTGGAGCAGAAGACGGCCCTTCTCGGTCATTCGCACGGAGGGGTCCTGGCGCAGGCTGCTCAGCAACTGCCGCTGGGTTTGCTGGGCTTTTGCGGGCTGCGGCGCCGCGCCGGAGGTGGTTTCCCCGGACGGTACGGGAGCGCCTTTCTTCCTTGCCGTGTCCTTACGTTCCCGGCCGGGCCCATCCGCATCCGCCTTTGTTTCACTGCGGAGTTTCGCGCGTATGTTGTGTGCGGTGCCTACGGAGACCCCCGCCTCCTGTGCCACCGCCCGCAGTGGCGCTTCCGGACGTTCCCGCATGATGTCCACGGCCTTCTTCCGCCCGGGCGCTCCGTCCACGGGGCGCCTGCGGCCGTCGCGCCCCACTCTCCTGTTCAACTGCGAGGATTTTTCAGTTGAACGGCGACGGATGCCCGCGACGGTCGGAGGGCTGAGGCCCGCCACTGCAGCGATCGCACGATCCGACCAGTCGGGGTATATGCGAACTATTCTCTCGGTGGCCGCTTCCCGCTCATCGGCCGACAGCGGAAGCCCGTGGGCTACGTTCGCTTGCACGGACTGCACGAACGACTCCGCGTCGCTGCCCTCGAAATACTGGACCGGAATGGTGTCATCGCCGCGCAGCATCGCGGCCTTAACCCGGTGCATGCCGTCAATGACCCGCAGGGTCGAACGCTGAACCAGGATCGGCGGCAGCCCCTCCTTGACTTCCGCCAGGCGCAGGACGTGTTCCGGGTCCGTTCCGCTCGTCCTCGGTGTGTCCGTAAGTATCAGCGAAGCGATAGCAACGGTCTCGATACGGCCGTGCCCGATGGTCCTCGAAGGTCGTGCCGACGATGGACTGCCATAGTCTCGGCCTCCCGGACGGACTGGCCCGACAGCAGGCGCTTCAACGAGATTGTCCACCCGCGTGCCTCGCTCTCACTCGACCGCCATTCGTCCATCACGCGAGCAAGTGACCCATGTGCCGGCCATTGCGCCGACAGCCGCGCAACTCGACCTATTTTTACCTCGTTCAGAAAACGGATCCAAATCACAGAAGGGGCCGTTCGGCCCTAGGCATTCGGACAAGGAACAACACCGTGCGCAGGATGGGCGATGATTACTCAGCCAACAGAACCTTCCCGAGTCTCAAGACGTGCCCTTAACAGCCCGTGGGCTTCCTGGAAGATGAGGTCTAGGTACCGACCGAGGACTTCGGCCGCGGCACCGTGCCCGGCATCGCGTGTCGCTCATCGACGACGACCTGGCCCGGCTGCCGCTGCCGACCACTGCCCTTTAACATCCGCGCCTTCGTACCGGTCGGCGACGTCCATCTGCTGCAGATCGAGCGGGGCTACTACGCCGCCCCAACGGGGCGGCTGTCGCCCGACATCAGCAAGGACGAGCTCGCCGTCGAAAGAGCTGCTGGGCGGTACGGGTGCGCTGGCGCATCGGAGGCCGAAGGCGGCCCGAGCCCCGCCGATTGTTTGGAGGGGCGGTAGTACTGGCCGGGATGCCCCAGGAGGGGCTGGACTGCCCTGTCGGCGATCCGGCGCCGGCTCTGGACGAGTTGCGTGAGCGTGGACGCCTTCGCCTTCGACAATGTGGGGCCGATCGACGCAGGGCTCGCGGAGCAGGAGCCAGGGACAAGCTGACCGCGGCCGACCGAGTCCTGGCCACCGTGCTCTACCTGCGCCAACTCGGCCCCCGAGACCTGCTGACCAAACCCTTCGGCATCAACGGCAGCACCAGGCGGGGGGTAGCTGTGCACGACTGGACCGCCGTCGACTGCACGTCCGCACCTCCTGACGCCACCGCAATCCGCCTCCACGGTACGGCGGTCCCCCCGTTCCTATCGGACCTCGGCGGCACACGGTGGCCGGTTCCCAACCCTCTGGTCCGTATATATGGTGATCTCCACAATCTGCGGTAGCCGCATTGGCGGGCTCATGCCCAATGGGGCTACCCCATCCCGCCCACGGAGAGTAGCCAGTTGAAGACCAAGCCGCGAAGATTGCAGAGAGCCGTCACACTCGGTGTGATCGCTCTGGCCACCGTCAGCCTTCAGTCCGTGGCCGCTCAGGCGGCTCCCCACCCGGACCCGAACCCCAGCAACCGTATCGTCGGCGGCACCCGCGCCGAGCAGGGCGAATTCCCGTTCATAGTGCGACTGTCGATGGGCTGTGGCGGAGCTCTGTACGCCAAGGACATCGTCCTGACCGCCGCCCACTGTGTCGACGGCTCCGACGCCACCGGTATCACCGTCACCGGCGCCGTCGTGGACCTGGAGAGCCCCGACGCGATCAAGGTGAAGTCCACCAAGATCCTTGTGGCTCCCGGCTACGACGGCAAGGGCAAGGACTGGGCCCTCGTCAAGCTCGAGAAGCCGATCGACCAGCCCACACTGAAGATCGCCAAGGACCCCAAGTACAACGAGGGCGAGTTCGACATAGCCGGCTGGGGCGCCGACAAGGAGGGTGGCCAGCAGCAGCGCTACCTCCTCAAGGCCAAGGTGCCCTTCGTCGACGACGCCACTTGCCAGAAGGCGTACGGCGACCGGCTCACCCCCGGCGAGGAGATCTGCACCGGCAAGCTCCACGTGGGCGGCGTCGACACCTGCCAGGGCGACTCCGGCGGCCCGATGTTCCGCAGAGACGAGGCCGGCGAGTACGTCCAGGTCGGCATCGTCAGCTGGGGCGACGGCTGCGCGCGCCCCGAATCCCCCGGTATCTACACCGAGGTGTCGACCTTCGCGGGCGACATAGAAAAAGCGGCATCGGAGCTCTGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP023688|823841:892841|826673_827171_+|WP_003986996.1|DBSCAN-SWA
MAVRTQFPVEHQCGHSVVHDLSDRPADRRAGFARWLTGKDCTDCWKAARDADTGSKEAWLAAKRAEEQQAAAEWAEKFDMPPLEGPERVLDWGERSRHQLMTAAHTALVVEGAWDEPDWAELEEKARVVTRAGWWIDQRDAEGSDLLELLDAATEQDRGTENPFR
>NZ_CP023688|823841:892841|880404_880902_-|WP_053799566.1|DBSCAN-SWA
MNPAPQQALETVGRARDTELAVRIANKARAALAHERTALAALAAADAGASHRAIGAKLGISHVAVGALVAKARALPPLVEGRAGRSPLHIAMRHAAGEIDRDTLVEALATWPPFAPPDTLPVGLPDHGAALPAPGAFDEVHDALVHGYLDEDVYDAILRRRAEQQ
>NZ_CP023688|823841:892841|856463_857090_+|WP_003985724.1|DBSCAN-SWA
MTTLRSAVHQAASLLLSYPDGDWSVRLAAVAETMCPLPGEAPAALLRYCDHARGVPLLDLAACYVLTFDRSRRRTLHLTYYTDGDTRRRGAALARLKALYRTHGWQPSDGELPDYLPAVLEFAARCPEPGLRLLRDHRPAVELLGHALEKHRSPYADVLRAVRDTLPAPAAGDRAAALALARTGPPSENVGLDLFPADASAHSEGARR
>NZ_CP023688|823841:892841|858041_859052_+|WP_100246722.1|DBSCAN-SWA
MREGIGRLPSACFASVMAAGIVSRAAASVGAHTVARLLLSLGVLLYVMLVGATAWRIAAHRGRVAQDAADPARAFGFFTFVAASDVLATNLATGDWRPFAIVLLTGGALCCAALLRTVVTAARSRPARADGSWFLLVVGPQSVVVAATELRAGPATAVAGLCCWAVGVLAYVTITSLVWTRLRRHGVPPAELTPVYWIAMGAGAISVLAGAGVLLSASWYEPVRTVVTAVLMLVAGWATVLIPVLLGAGAWRHIRHRVPLRYEPSWWSAVFPIGMYAVATQQAARATGAGLWEKAGQAAAWAALTAWALVGTAILAQWPRSGPTSLRGRSRRPPAG
>NZ_CP023688|823841:892841|885834_886704_-|WP_129821011.1|DBSCAN-SWA
MDLTRFWQGNAERARRLILKNLAREDLAMSRSVTHGARSGRHVIMAVLVASTLVAVVPSPAQAVTPEPGLATWNIQSKAGNWADVGKLVNEHKTDVVALQEVPKNPPAGAKAVQTGGRLEEYEWNIGSTSRPNIRYLYVLREPSKNLGLVTKWQPGTANIKTITGPYRPLLCVNDTNTSTLFCSAHASASGGGDAAALVRNTANEAKVLNIPNWAVLADFNRAPDDLAKDKKLPSAAHIYRPNDPTQLSGGELDYMVSNVDSDWRRGHVEVARSGASDHWAVVWSPKPN
>NZ_CP023688|823841:892841|847119_848013_-|WP_003986272.1|DBSCAN-SWA
MTGLKLFHTMNGNVAEVAPRLAEVEADVQHLIEAHMETMLGVRFLASEYGTGPVHGGRIDSLGLDENDAPVVVEYKRGTDAGVINQGLFYLAWLIDHRAEFGHLVRERLGAAAASRVRWSAPRLICVAGDFTRYDVHAVREHRRSIDLVRYRLYGEQLVSLETVASVTGQTATSGTARRRRAANTTRGHLSQGAMAELAAAVDETLLGLGPDITRAENRLYRAYRRLRNFACVCPPQKSKLLVYLKADPQETGLVPGLTRDVTGLGHHGTGDLEVQLRTERDLERAQDLFRLSYATT
>NZ_CP023688|823841:892841|834926_836714_+|WP_003987072.1|DBSCAN-SWA
MPPSSNSSDGYDIAFRLLLGVLAIVVPFSNLAWLSGNITACLTGLPWAPYQPTAALLHPDQLWPQATETSLLVGARIVPGAVLLALGAAAGVLWARHKNRSGSRKKKITGMAKARDIEPLMAKAIEAKARSLRPSLKDTKHIEAKDTGILLGNLQGTPHEVRMGYEDVAVAIMAPRSGKTTSLAIPSILSAPGPVLLTSNKAAGDAYTTTLDARAEVGRVWSMDPQQIAHATREMWWNPLATAKTLDGANRLAGHFVSASVDASQQGDFWSKAGSNILSQLLLAAALDERPITDIMAWLAFPADRTPLDILRDHGFAAVAAQLKGTVEGPPETRDGIYETARQYAAALLNAEIAAWVTPQKDVAEFRPSQFVTSTDTLYLLSKDGGGGASALIAACADAVMRAATAEAERAGGRLDPPALAILDEAANVCKISDLPDLYSHLGSRGIIPITILQSYRQGQKVWGDAGMDAMWSASTVKVIGSGIDDPDFADKLSRMIGDHDVETTSISHSESGKSTSVSMRQERILPADAIRALAKGTALCFATGMRAAMLDLRPWYAEPGAKELSAASARASKAITERAVAKAAPAQTDFTTAT
>NZ_CP023688|823841:892841|831979_832783_+|WP_030185265.1|DBSCAN-SWA
MKKKQWHNWGAGEQAQQHYLVQPRALAGGGDVRHVSEFLRACGWRDKSKTDGPLFMQSPDRAVRIAYDPYVQPGGWSIHGAASRHQPEWWAHLGRQTPVEIVAGLTDALTQPRSAHAPNVWAPLHGQRWRTEPDAEQVTATSPDGSAWMQYHQSPDGAAMWWSGAKDEQGNGWNAQFASSTPMHLVQAFSAALASPEPVMRPLGRVPPSTQIKTTSVSVLPSQLSAWQQARITAARAATWARNTARSARPRTAARPHAHAGGPRARR
>NZ_CP023688|823841:892841|889909_890977_-|WP_078605230.1|DBSCAN-SWA
MDNLVEAPAVGPVRPGGRDYGSPSSARPSRTIGHGRIETVAIASLILTDTPRTSGTDPEHVLRLAEVKEGLPPILVQRSTLRVIDGMHRVKAAMLRGDDTIPVQYFEGSDAESFVQSVQANVAHGLPLSADEREAATERIVRIYPDWSDRAIAAVAGLSPPTVAGIRRRSTEKSSQLNRRVGRDGRRRPVDGAPGRKKAVDIMRERPEAPLRAVAQEAGVSVGTAHNIRAKLRSETKADADGPGRERKDTARKKGAPVPSGETTSGAAPQPAKAQQTQRQLLSSLRQDPSVRMTEKGRLLLQWLGILTLDAKELQQFADSTPAHQLLSMAQLAQDCSATWRQLATELHRAVRRGP
>NZ_CP023688|823841:892841|841309_842431_+|WP_030185293.1|DBSCAN-SWA
MHPRPSAPRPDEDAELADAHPPAPVHYAEQALLGALLLEPARLDGLGPLAPEHFDAPAHSALYTAMHTAPVPDAEQHRRAPVWLDRVLQAARPQAPGLTASYLHTLVHRCPWPGHAAAYAHMIQADHTRRTVREHADRLAQAATEASLPDPTATVLAQCDTLSSFLNTLSSRFAPHPGSLPRTPHPAPARRTAGEEALEEERALLACATAQPSRLREMRWLQPDDFVLPLHGQLFTCLTALVHRREPIDPVTVLWEAQHQHLLHANFTPADLIGLLATPVGTPEHWGEKILRRALLAQAHTTAVQIRAFTDDAANTPHQLATGSRRALANLTALGTRWQRASHAPATPRSPAVPRAGPRLRAAPAPPTTRVSR
>NZ_CP023688|823841:892841|842852_843476_+|WP_030658806.1|DBSCAN-SWA
MQQVHERAAATREKILRAASEVFDAYGYSGASISKTLTRTGITPGALYFHFSGKQCLAHAVMLGQGDGLKLPGGEDGLQRLIDINLYLAGELQTNALLRAGVRLAVEQGEFGTPDDAPYQYWVRLFASQLLAAKEKDELLPDVDVQELAWTLVSSYSGTQLLSQIATGRTDLHARLVALWRYLLPGIATPAARSRVTFSSQWDCPAA
>NZ_CP023688|823841:892841|892046_892841_+|WP_030182092.1|protease|DBSCAN-SWA
MKTKPRRLQRAVTLGVIALATVSLQSVAAQAAPHPDPNPSNRIVGGTRAEQGEFPFIVRLSMGCGGALYAKDIVLTAAHCVDGSDATGITVTGAVVDLESPDAIKVKSTKILVAPGYDGKGKDWALVKLEKPIDQPTLKIAKDPKYNEGEFDIAGWGADKEGGQQQRYLLKAKVPFVDDATCQKAYGDRLTPGEEICTGKLHVGGVDTCQGDSGGPMFRRDEAGEYVQVGIVSWGDGCARPESPGIYTEVSTFAGDIEKAASEL
>NZ_CP023688|823841:892841|837737_838538_+|WP_003987074.1|DBSCAN-SWA
MTAPTAPAEKLLLLGGDFARQHDYLSCLRLDGLSPATALTQQSIPTQDLARLALDIVEGLDAQRMYHSPEIRTVYARVRQLAHLAIDTADHLLDAEDILDDTYAGVPAKGEGPLLTYRQALETANSRLILVRKLTAPAPQDTLTAAELFVTERRRRGEIPPQQPPAFSPAQYTALRAVARGEVTIADDKPYLHRDDWRIALSTLRSLEDRGLVAREKCPLWLHDERVHLSADGRRDLIATFGRPPAPARTAARPAPAPKATPSRSL
>NZ_CP023688|823841:892841|867680_868079_-|WP_086026279.1|DBSCAN-SWA
MANTAQAAAVPEWVVKFMGAIDTLEFDEGFAPLTEDTDMFFGTAHIHGIEAIKAFFVKIDEPLVITHEVLEFWTAGDGVRLLRGEATMAKKSEPDRVVRAPFTHIFYLADEDPVRVRELRFTAGPLQTDAVM
>NZ_CP023688|823841:892841|827703_828489_+|WP_003986994.1|DBSCAN-SWA
MTLPVRRPGRALALLTAKARATADLGAASWPDRLAQDLHDLDADWRESAEVCADVAWTARAAGHSVLDLLPPAQVTAAGPDPVTTRTFRHLYLSALRFDFRCPTLQALVEQLPDTALRSLDCYSRALYAFALLGQSRPAGLTVMDEVLAEAGEHDKTLHVLLHGLWLGQDLDQGTQRLLALSARPAFAPGTDPIVLFRRAGALRRLGRYDDGLAALDRALDLLPPGDIAVHADLVRERSLICAARDLHQRLPARAFGGTPT
>NZ_CP023688|823841:892841|832811_833168_+|WP_003987067.1|DBSCAN-SWA
MPALTPDAIRTATETLSRLTDYLRDSPDPQQALDLVEPLLDEYTGLPVQLADALRALARAVQEHPDTPRSLEADLLVMELRTAAWEQADQHTLHYVLDDLRALHASACGTEAECGPCR
>NZ_CP023688|823841:892841|861615_862641_+|WP_003985719.1|DBSCAN-SWA
MLRGKGIHYDTGTFPNGDTSRPVFDPRDAERDIQVVAEDLHCTAVRITGGDPDRIETTARYAAQAGLEVWFSPFPCELTNAEMLPLFADCAERAERLRRDGAEVVLVTGCELSIFARGYLPGDIFNERVPVLAGPGREAALRGIPDKVNTFLAEVVDTVRPLFGGRISYASCPLDGVDWTPFDIVGLDAFRGQRNAATYRADLRAECARGKPVAVMEAGCCTYRGAGDHGGAGWYMAKESDGITLRPGLVRDEGEQVRYLEDLMTVFEEVGVDSAFWFSFAGFSTPHRTTGPDEDLASYGIVKILDEHSDYPVSQRTYPDMPWEPKEAFHALARRYGADGK
>NZ_CP023688|823841:892841|827269_827707_+|WP_003986995.1|DBSCAN-SWA
MNPPSRTPPPTPAFAPTHDPLTPARDITHQHFQAGDQVVVLKGVAGGELWGDAMRVVAPSWHTPTDEDGWRLRDATGGAQTYVTAHPRYLVHLSRRCPDCLIYLRAVEDHLLAKYPESDTLVDCGWYTTTALGQLVHIADAQSGR
>NZ_CP023688|823841:892841|848196_848886_-|WP_003986271.1|DBSCAN-SWA
MTALLDTLGSPPGLGLLPADRCAQALGLTCVTISARAGGHAPELIWSAPDDRLGTALEDVQFTLGEGPTLGCLRDGRTVTEPDLSRVAGSRWPTFLPEALQAGARALFALPLAIGAVRLGAFTGYRTRPGPLTLQQHLDMHTFIDTATFLLLALLPGADGRRDPATDLATLHRAEIHQATGMLAVRLHLPLDQALLLLRSHAYSTGRPILDLARDIIDHRNPPGLTGPT
>NZ_CP023688|823841:892841|869719_870175_-|WP_003985711.1|tail|DBSCAN-SWA
MRFVPRLAAAVAVSAALATALAGPASAAGHQLPVGHRSPVVLGAVQADSPGRDDGSNRSLNAEWVTVKNTGRHAVNLTSWTLTSRRTHATYRFHLRLGGHQQVRVHTGRGHDTMRDVYQDRRTYAWDNHRDTAVLRNDHHLIVDTKHWNHR
>NZ_CP023688|823841:892841|840065_841310_+|WP_003986279.1|DBSCAN-SWA
MIVDLFAGPGGWSYALSLLGVRDIGLERDAWACRTRAAAGQLTLRTDVARYPVGPFVGRTTGVIASPPCQAWSMAGKRLGLLDQPLVHQAVADLAAGRDTRDKLLGACRDERSLLAAEPMRYLHALNTVGEPEWVAMEEVPDVAPLWKQYAAILRSWGFSVWCGILNAADFGVPQTRRRAILLASRSRPAEPPPPTHAQHGEPETLFGPGRAPWVSMAAALGWGATDRPVPTVCAGGGPGGGPEPFPSGSRKALADARDRGTWQHPPRPAGTERRLRRRSQPAVAAHESPPPSARPAPEWAWSLRTNSQTNATVRRADEPAGTLFFGHRANECLWIAEPATTTAGEDAPVPEAIRITAAEAGVLQTFPADYPWAGNKGQQFSQIGNAVPPRLAAHLLAPHLGRPLGPDDFTLAA
>NZ_CP023688|823841:892841|834041_834587_+|WP_050498949.1|DBSCAN-SWA
MQHLDDYVHDSKAILDAWDAYSDEHTDLDGWPHDDHAYGLRQSQRDADTAAAFENIRAGARHLLATAEAQLRSMPTGAVQSHWVYRLGVLHTALDRLDALHEQWLLTRGSFPADVRPGTPAFDEALAEHHAESWSYLDDWATHGHVLKDINSASRHSSTPLAPPPTATAAPAPGRSPSVRR
>NZ_CP023688|823841:892841|843777_844059_+|WP_003986275.1|DBSCAN-SWA
MAERQMLMTTQEIRALINAALAAPSIDLAVPLGMSLMLREGLRTTVLTALSRADYHPAVDDVPGSLTYRDGDHVRVATLSPETEFLLAAHLEQ
>NZ_CP023688|823841:892841|829563_830052_+|WP_078575752.1|DBSCAN-SWA
MRTAGYHVDCDAGFETDARPVSYLPLGASVAHLAERIRTATTTEEAADALTELTAAHDGVLAALGDILAATAEFHEGLGDAADPHIARRLRYLADERLHTLRTDLCHTRNALADRHAPHPGRSTCTEQVPATERERSAVCACPPPPRTALAPPPAVAAGPRR
>NZ_CP023688|823841:892841|878100_879396_+|WP_151416119.1|DBSCAN-SWA
MIPTMATHGCPPEQHRVQLQDGVMVTEECALCGYRITYGPVGHDRAYPPARPPLAGPRRNGGLIAAVLVAALVAGGIGGGIGFWAANRNDTNSTTVSASGDPEALNRKPTSVSGIAQKALPSVVTIEAQGATGEGGTGTGFVYDKQGHILTNNHVVASAAQGGRLTATFSNGKKYDAEVIGRAQGYDVAVIKLKNPSDANLVPLPLGKSANVQVGDATIAIGAPFGLSGTVTTGIISAKNRPVASSDGGGATPSYMSALQTDASINPGNSGGPLMDATGSVIGINSAIQSAGNGGGGFGGESQSGSIGLGFAIPIDQAKRVAGDLIKKGQPVYPQIGAQVLMRDTGDGATTAQNGGADGSASVTPKGPADQAGLKPGDTITKLDNTIIDSGPTLISTIYQHKPGDKVTLTYKRDGKEHTAQVTLGQRTGDK
>NZ_CP023688|823841:892841|881258_882182_+|WP_003980773.1|DBSCAN-SWA
MFHLIRRRVRTAALTVSAIAALTFGATAPTGAAAAPAPAPGKQGPTSVAYVEVNDHSMLNVGKYTLANGGGNVFDVAVIFAANINYNTDTKTAYLHFNENVQRVLDNVATEVRPLQRKGLKVTLSVLGNHQGAGFANFPSQQAASAFAKQLSDTVAKYGLDGIDFDDEYAKYGTNGTGRPNSSSFVHLVTALRANMPDKIISLYNIGPSASRLSYGGVNISSKFDYAWNPYYGTWRVPGIALPKTKLSPAAVAIGSTSQSTAASLARRTVREGYGVYLTYNLDGTDRSTDVSAFTRELYGSDAVYTP
>NZ_CP023688|823841:892841|845419_846988_+|WP_003986273.1|DBSCAN-SWA
MSYPFSVADIGWIPVRVRSDLDADETAELRSLLPEASPGECTRVGLRHLFQGAHLFADLDFAVPPVEAVARRLLAAVTARVAGLDTGTSAQWPDARDDLLATGRFDADRVDEYLKAHAHRWNLYYSAQPFLQDIRLAQECGKGQAPGRLVMDRPSGSNAVWTTHIAQDVPVAGPDAVQWLLAWYGYGPSGTGTHRTHGSRKGGSCKAGPYRSLVSYFPHAPERLFVSLVASVPGPSAWPTGSGPDLAPWERDELPDPLAPDAACGPVSLLTRRTAHALLLTGDDAGQTTSCKITWNTAVDLPAAVDPYVIERTQGGPVRADRARSAWRDLDAMLLKTQPGSKSTLRRPTVFDAVAELAPQVQRQLGVRVLAWDQERQEKDNQWYAATTPPVLQHIEEADPQGAAAIATARRSAEAAAGDLARALAAAWLDVHVKRDPQQRHGFVEAARTRYWERAEEEFWQAVRAPDPDRRPAFRRLALERFDQATATLKATVHGMSAVAKARAQLTLPRTHATRSTRKRTR
>NZ_CP023688|823841:892841|825635_826169_-|WP_003986997.1|DBSCAN-SWA
MHGRLDEVVPAPVRAQLQAAEASLRKVATADLPAPVLMACAQRVVAVVGTMCGKLSEFAAPGADNFLNAERCCGGASTMLADNLGVHLVEKYGSAARDCDLSEVRDGILTLKWRATELDITEMAAWLAGSIAKADAAFESVVHRSTAPKKLCDTAAAAAELSHQAWAWLAGDSGGWP
>NZ_CP023688|823841:892841|865449_865797_+|WP_003985715.1|DBSCAN-SWA
MCAESERRARALVRCGIGPGDRVLRLAEPGPRRIFDDRVYVRGACTLHALRLTLDGDARFFALLRGWHDAHRGGSCDTKTFLAHAEAVADRPVRPLLCRWLSEPRLPPLPPRPSH
>NZ_CP023688|823841:892841|830920_831328_+|WP_030185261.1|DBSCAN-SWA
MANLADEHGTDVEICVKPLTTTIHADTPTGAPERLHTLLDQLGLERQEVRTADPVYIWHVVPEHLAADEQKRLATRAIPALLQAGYQVNCTSAVFDEAVYQQALRDLHATQSHPAVQRPAPAASPARPAPPRRTP
>NZ_CP023688|823841:892841|824766_825450_-|WP_100246748.1|DBSCAN-SWA
MSVASATMALPCTTPPPLRGRLVAQSFTVHLAFGSHRIENVTLQWGVGMDGDTRRDAPSWGTDIEVPAVIELLDLITAGSVTAEQARDKLVRLAVAINERKNREYEEMIELMEQPTPRAVREESCFDDRWVYAVSPDGAPDSIKIGVAKDIAQRIKSLQSGSATTLELRWSARGGYPLERYLHEQFNVRRTHGEWFDFESCPDPVAEIDNAAHAFLRQYAEESLANS
>NZ_CP023688|823841:892841|836798_837410_+|WP_003987073.1|DBSCAN-SWA
MAFLDHNDVVIGSTDDGHTFVLLNRALPAAQRILTDHGFTAHQPSGPGRPLYLLPPAYAGEQANTRTGEAMHFLFQHTWDVTDLSWTTRWNPDEPLPEPDVHFHVSGERVTATARTDAARRILANHGFTPTREGYALPVGTDETRQLGAVVQAETALSMENLGTRIRLGFRTPEDIPAAPARTSSHTATPPAAPVPDRPRRTR
>NZ_CP023688|823841:892841|839190_840069_+|WP_032922125.1|DBSCAN-SWA
MLALSAEGILPRVDCAIFADTGWEPAAVYAHLDRLEKEVAEPAGIPVLRVSAGNIREDALNPGHRFASMPLHVLNQDGKAGMTRRQCTGEYKIKPIKKQVRALLGYPYPRRIPKGVFVEQWVGISTDEFHRAKDADVAYMRNRHPLIELDWSRADCLRYLKQRGLADTPKSSCLGCPFHGNAQWRHIRDHSPAEWADVVAFDAAIRSGNARANASGNRLLGQAFLHRSRVPLDQAPIDHVTAAEWAARQAELGDQAPDGDARVVLEEGVADGCSPWACRGEQPTQDDFGLAA
>NZ_CP023688|823841:892841|851135_854825_+|WP_139679716.1|DBSCAN-SWA
MAGAAAERLLRLGRQLQGAATTPDGRAVYRTDQQVNDAPYRERWAHDKVVRSTHGVNCTGSCSWQVFVKDGLITWETQQTDYPSVGPDRPEYEPRGCPRGASFSWYTYSPTRVRYPYARGVLVEMFREARARLGDPVAAWAEITGDAAKRRRYQQARGKGGLVRIGWDEALEIAAAAHVHTLQHYGPDRIAGFSPIPAMSMASHAVGARFMALLGAPMLSFYDWYADLPIASPQVFGDQTDVPESGDWWDAAYLMLWGSNVPVTRTPDAHWMAEARYRGQKVVVVSPDYADATKFADEWLHPHPGTDGALAMAMGHVILRECFVQRQVPYFTDYVKTFTDLPFLVELEPHGASFVPGKFVTAAGLGLSEEDDGGENGQWKPVVFDAGRGAPVAPPGTLGERWSEGGAGRWHLDLGDVDPLLTFHEAQGAASVEVLLPRFDQGAEGEAGTVRRAVPVRELGGRRVTTVFDLLLARYGVHRQGLSGQWPQGYDDAALPCTPAWQETLTSVPAGAVVRAAREFAHTAEKTRGRCMIVMGAGTNHWFHSDTIYRSFLTLLLLTGCQGVNGGGWAHYVGQEKVRPYAGWQQLQSAADWVRPSRQMAGTPFWYLHTDQWRYESYRADALASATGRGLFAGRHTADLVAQSARLGWMPSAPTFSDNPLTLGERVRAAGSEPGQWVAGQLRDGQLRFACEDPDDPANWPRVLTVWRANLIGSSAKGNEYFLRHLLGADDNASAEEAPSEARPRDVTWHEEAPRGKLDLLLALDFRMTSTTLMADLILPAATWYEKHDLSSTDMHPYVHAFSPAIIPPWQARTDFEIFHGLASKLSELARGRLDTRYDLVATPLTHDTPGETAQPGGTVPDWREAGRPQPGHNLPAFALVERDYTAVAAKLASLGPLAEEAGMTVKGVTVYPRAEARWLADRCGTAADGAASGRPLLDTDVKFCEAILALSGTTNGRLAAEGFARLAERCGPDSGLEELAASVAERRIVFSDTQARPVQVAASFEWSGKEGPERRYAPFTINTEHRKPWHTLTGRQHFYLDHDWMAELGEQLPVYRPPLDLAALGEHPPMAGVEGARSVTVRYVTPHSKWSIHSEYQENLLMQTLARGGPVIWLSVQDAARIEVADNDWIEAVNANGVVVARAIVSHRMPPGTVFMYHVQERLVNVPKSQATGRRGGVHNALTKLLIKPTHLIGGYGQLSFAANYYGPTGNQRDAVTTIRRRSQNVEY
>NZ_CP023688|823841:892841|854859_856467_+|WP_086026280.1|DBSCAN-SWA
MAQVAMVMNLDKCIGCHTCSVTCKQTWTHRSGTEYVWFNNVETRPGQGYPRAYEDQERWKGGWRLKGDRLVPRSGGRARRLARLFANPELPALSDYYEPWTYDYANLTTAPLGDDLPTAPPRSLIDGRPTDITWGPNWDDDLGGGPDHLADDPVLKKMNERVRLEYEQAFMFYLPRICEHCLNPSCVAVCPSGALYKRIEDGIVLVDQDRCRGWRMCVTGCPYKKVYFNHHTGKAEKCTLCYPRIEAGQPTVCSETCVGRLRYLGVMLYDPDKVGEAARVTDEKDLYEAQLTCFLDPTDPGIARAAEESGIPHDWITAARRSPVYALINTYRVALPLHPEYRTMPMVWYVPPLSPIVDSLTRTGHDGEDPASLFGAIDALRIPLDYLAHLFTAGDPAPVEAALCRLAAMRAYMRRINLGDPRDPAIAEAVGLGADSIEAMYRLLALAKYEDRYVIPTSYTGTVPPDTPDDGCSLDADGGPGMYDAGLPGMEAFHTPPATEPAPAGDGLRGRVNLLNWNGRGTPSGLFPRRRENER
>NZ_CP023688|823841:892841|863588_864047_-|WP_003985717.1|DBSCAN-SWA
MEPDLPDDEFADEDDDDFVGLIDCDECGKIMEPDLFDGDDPLLAALPDSSAIYEDPTNDGKRLVMLCSPECLEKIQERFGRQPFVREELWAGKIVRSVMKHPQGVSPRVLEQETGLSPAQILAGFAWVERMRPAGRGKGPGPQAGGAGGASR
>NZ_CP023688|823841:892841|868781_869444_-|WP_100246721.1|DBSCAN-SWA
MLLGTVLLTGCSGGNGGGSASGKHRESAGASGAAPVRSAASGSGGAAASLIAKGPGPQAHYTVQAQPAPGMCHYRTVHGQPLQDASCTPGALNPDVTQATLKTTVCRTGGYTSKIRPPVSVTSVEKAANARSYGYTAGLHDAEYDHLVSLELGGDPNDARNLWVEPPSPGHTPGSGPNNPKDAVENKLHQSLCSGQITLDQAQQAIATDWTTALATLHLT
>NZ_CP023688|823841:892841|830075_830834_+|WP_030185257.1|DBSCAN-SWA
MHDHENSERLASYADVLAGELPDAWTSTYHPPGAKHDLAELGDRIWDLDLIAESLAEHPLQQAAVLSRPDGAQLAVLERHDERDGFLIAAVAPRALPDEAYRAVPEPNGIALTDDPFLSAEQVAGDLLARYDTALAQVRHNAAADVQPSQPERVVLTWQPDGSLAAAPVGETAAAVLAANSFVPDQQTGIYRLSGDDTTVQARAVRETGRQLGAHGITTALQHPSGRIAPTATPAAVPPAPATSRTPANRAR
>NZ_CP023688|823841:892841|884177_884995_-|WP_086026205.1|transposase|DBSCAN-SWA
MASNRWGWIVPDGLWEITRPLLPPPRLRPQGGGTANTDDEAVFAAIVYVLVSGCAWRALPPCFGISKSTAHRRFLIWSRAGVWGRLHQRVLDRLAGRGLLDLTRLVLDTAHVRAKKGGELTGPSPVDRGRPGSKMHILSDAAGLPLVVGLSGGNTADSDGLKPMIGGYQTKHDPERGRNYPVGKVHADKAYDRPHLRRWLRGRRIAVRIARIGVEPSDRLGRHRWVIERTLAWLSGYRRLNPRYERHHDNYLAFLGLAAAIVCHKRHAQLTT
>NZ_CP023688|823841:892841|838719_839085_+|WP_129820972.1|DBSCAN-SWA
MARSLHARLYGLPTAPSPLPTALDELLQVLGTARDGDQKQAVLVQLADQLRNAAEILEWARDNARQLPAPIWEWLRDATDTTRHLADGLDSVRPSFAAPQAPAAPLPPPAPAPPHAAPARR
>NZ_CP023688|823841:892841|857086_857878_+|WP_003985723.1|DBSCAN-SWA
MTHVHIALWGVLPYLVLAVLVGGTAWRYRYDRFGFTTRSSQLHESRLLRIGGPLFHYALFLVIGGHVTGLLVPESLTEHLHVSETMYHLFALAVGGTAGIAAVAGLGILLYRRLRVPAVRAATSRSDHLVHPLLAAALLAGLVATASSATNPYDYRLGVSVWFRSLFALDPDVAAMAQAPFTYQLHALLGMALFALWPFSRLVHAFTAPLGYVIRPYVVYRSRRGVGGRGPYRPGTPSQAPRVDHPARKAAPTPGRTARRTPG
>NZ_CP023688|823841:892841|883352_884126_-|WP_003980775.1|DBSCAN-SWA
MIRVMIVDDEILLRTCMQRILECEPDIEVPVVCDGRDVLEAVDTHRPDVVLLDLRMPDVDGLTALEWIRSRPAPPTVAILTTFLTDEDIAAALRSGAAGFLMKDATPQELAHVVRVLAAGDTVLSAAAARIVIDGYLDTGMRHDEPDPRLGTLTEREHQVLELLAEGLTNAEIGRHLLLSASTAKEHVSTILTKLGLTNRVQAAVVAHRAAAARRRPLATPPGPAERSGEPGAARGGSGPTAHPPHRHHPTPRRPAP
>NZ_CP023688|823841:892841|877437_877899_+|WP_003987177.1|tail|DBSCAN-SWA
MIRSARLAAVALGAAAVVTAAALPASATGAHTPPAAYRSPVLIGAVQADSPGRDDGSNRSLNAEWVTVKNTSRRAVNLDNWTLTSERTHKTYRFHHLRLAGHQEVRVHTGHGRDTWRDVFQNRRDYVWDNHRDTATLRNDHHRVVDTKHWGRR
>NZ_CP023688|823841:892841|875524_875884_-|WP_086026305.1|DBSCAN-SWA
MQTRPAIDLARGILMATFSLTPEAAWAALVNTSQNTNTKLHRLAEDLVNSVHGPLLSENVRGHLGAAVAKAKQTPPKPDAGPAPRNSVPRSGASQSAGDPCPATSAQRLRRRRLGGLLS
>NZ_CP023688|823841:892841|831602_831983_+|WP_003987481.1|DBSCAN-SWA
MSHPTPYTVRLADEITRQLGQLADHLAQLPPQEAPQALARILDPDNGVFGGVTHLVITGSVFAKAEAERGALPAEVWLALGRASNELNDIALGLDEHRETLQHASAHPATRAAPPVPAPLVVRRRR
>NZ_CP023688|823841:892841|862619_862802_-|WP_003985718.1|DBSCAN-SWA
MPLLLGEAMRPVEPLCSWFRRLAMGRMDPKSMKAYAHTAVLLAGFLRARQQDLLYLPSAP
>NZ_CP023688|823841:892841|882585_883356_-|WP_003980774.1|DBSCAN-SWA
MTLGNAIYDQKLANVYDRMYPIGEDTDQAVEFIAAHTPPGGRVLELGVGTGRIAVPLARRGLTVHGLDGSEAMLAELRRRDPQETVTAQLGDFTEEGTGQVFDTVTLVLNTFFVAITKEQQLGCLRLAHEQLVPGGRFILEAFDPAPYHHLQKPDFSMRHLDERAVMLDTLTVDRSQQLMLSTHTIVDGGGAPETRKHVLRYAFPFEIDLLAQLSGLRLVDRSEDWRGTPYTASSLRHVSVYEPDTHSPWPSATAG
>NZ_CP023688|823841:892841|870559_870826_+|WP_078951183.1|DBSCAN-SWA
MPLYMAWRGALGDTGLWWSQTRNGTTWTPQQQVLGATSMERPALVLQWDFTIPAGQTRSFEPKGCPVWGGDYPVRAVLWRRAMPRMAW
>NZ_CP023688|823841:892841|870771_871539_-|WP_030191976.1|transposase|DBSCAN-SWA
MGGVMSADDPKWIEPFTGLSPAQFNRLVALVRRRGGDVQRGRPWRLPLEDRVLLVATYWRTNLTLRQVAPLFGISKSAADRILDHLAPLLAISPARRKREDTVYIVDGTLIPTRDRSVAASSKNYRYSTNLQVVIDANSRLVVAVGAPLPGSRNDCRAFTESGVDIACRGVPVLADGGYQGTGLLIPHRRRRGQETLSPQQEAENKVHRKARARVEHALSRLKNWKILRDCRLKGSGVHQAILGIARLHNTALTG
>NZ_CP023688|823841:892841|849003_849759_-|WP_003986270.1|DBSCAN-SWA
MTAEQERLSRVEEITSVFVELADTLVAEFDVMDFLHTLTERTTRLLPVDAAGVILLNAQGRMVDATASDEQTRRLELAQIEWQEGPCRDCIHTGAPIPDTPLDTHQAEEHWPRFTEWAAERGFAAAAAVPLRLRETAIGALNLFRTRPQALGEPDLRLAQALADAATIGILQYRAIRDQTLINEQLEGALGTRVVIEQAKGMLAERLDLTPDEAFTRLRARARHHQILLTDLSHQVINGQADPEQFNAPPA
>NZ_CP023688|823841:892841|875079_875376_+|WP_106972255.1|DBSCAN-SWA
MSAVNRMTIDALAILVRKAMRLRSVGGELLLAGPCPAVRKLIERTGTAPLLRAVAGRAAAVRALAQDGRTWHQVDLGAEPSTLFPDLPEHLEPYPRTW
>NZ_CP023688|823841:892841|823841_824609_-|WP_030191976.1|transposase|DBSCAN-SWA
MGGVMSADDPKWIEPFTGLSPAQFNRLVALVRRRGGDVQRGRPWRLPLEDRVLLVATYWRTNLTLRQVAPLFGISKSAADRILDHLAPLLAISPARRKREDTVYIVDGTLIPTRDRSVAASSKNYRYSTNLQVVIDANSRLVVAVGAPLPGSRNDCRAFTESGVDIACRGVPVLADGGYQGTGLLIPHRRRRGQETLSPQQEAENKVHRKARARVEHALSRLKNWKILRDCRLKGSGVHQAILGIARLHNTALTG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_030191976.1|823841_824609_-|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_100246748.1|824766_825450_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_003986997.1|825635_826169_-	hypothetical protein	NA	NA	NA	NA
WP_003986996.1|826673_827171_+	hypothetical protein	NA	NA	NA	NA
WP_003986995.1|827269_827707_+	hypothetical protein	NA	NA	NA	NA
WP_003986994.1|827703_828489_+	hypothetical protein	NA	NA	NA	NA
WP_078575752.1|829563_830052_+	hypothetical protein	NA	NA	NA	NA
WP_030185257.1|830075_830834_+	hypothetical protein	NA	NA	NA	NA
WP_030185261.1|830920_831328_+	hypothetical protein	NA	NA	NA	NA
WP_003987481.1|831602_831983_+	hypothetical protein	NA	NA	NA	NA
WP_030185265.1|831979_832783_+	DUF317 domain-containing protein	NA	NA	NA	NA
WP_003987067.1|832811_833168_+	hypothetical protein	NA	NA	NA	NA
WP_050498949.1|834041_834587_+	hypothetical protein	NA	NA	NA	NA
WP_003987072.1|834926_836714_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_003987073.1|836798_837410_+	hypothetical protein	NA	NA	NA	NA
WP_003987074.1|837737_838538_+	hypothetical protein	NA	NA	NA	NA
WP_129820972.1|838719_839085_+	hypothetical protein	NA	NA	NA	NA
WP_032922125.1|839190_840069_+	hypothetical protein	I1ZBF8	Salisaeta_icosahedral_phage	2.7e-47	42.3
WP_003986279.1|840065_841310_+	DNA cytosine methyltransferase	I4AZL4	Saccharomonospora_phage	5.6e-67	43.6
WP_030185293.1|841309_842431_+	hypothetical protein	NA	NA	NA	NA
WP_030658806.1|842852_843476_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003986275.1|843777_844059_+	hypothetical protein	NA	NA	NA	NA
WP_003986273.1|845419_846988_+	type I-E CRISPR-associated protein Cse1/CasA	NA	NA	NA	NA
WP_003986272.1|847119_848013_-	hypothetical protein	NA	NA	NA	NA
WP_003986271.1|848196_848886_-	ANTAR domain-containing protein	NA	NA	NA	NA
WP_003986270.1|849003_849759_-	GAF and ANTAR domain-containing protein	NA	NA	NA	NA
WP_139679716.1|851135_854825_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_086026280.1|854859_856467_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	1.4e-17	43.2
WP_003985724.1|856463_857090_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_003985723.1|857086_857878_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_100246722.1|858041_859052_+	C4-dicarboxylate transporter	NA	NA	NA	NA
WP_003985719.1|861615_862641_+	hypothetical protein	NA	NA	NA	NA
WP_003985718.1|862619_862802_-	hypothetical protein	NA	NA	NA	NA
WP_003985717.1|863588_864047_-	hypothetical protein	NA	NA	NA	NA
WP_003985715.1|865449_865797_+	hypothetical protein	NA	NA	NA	NA
WP_086026279.1|867680_868079_-	hypothetical protein	NA	NA	NA	NA
WP_100246721.1|868781_869444_-	hypothetical protein	NA	NA	NA	NA
WP_003985711.1|869719_870175_-|tail	lamin tail domain-containing protein	NA	NA	NA	NA
WP_078951183.1|870559_870826_+	hypothetical protein	NA	NA	NA	NA
WP_030191976.1|870771_871539_-|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_106972255.1|875079_875376_+	hypothetical protein	NA	NA	NA	NA
WP_086026305.1|875524_875884_-	ANTAR domain-containing protein	NA	NA	NA	NA
WP_003987177.1|877437_877899_+|tail	lamin tail domain-containing protein	NA	NA	NA	NA
WP_151416119.1|878100_879396_+	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.1e-12	24.9
WP_053799566.1|880404_880902_-	hypothetical protein	NA	NA	NA	NA
WP_003980773.1|881258_882182_+	glycoside hydrolase	NA	NA	NA	NA
WP_003980774.1|882585_883356_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003980775.1|883352_884126_-	response regulator transcription factor	NA	NA	NA	NA
WP_086026205.1|884177_884995_-|transposase	IS5 family transposase	NA	NA	NA	NA
WP_129821011.1|885834_886704_-	hypothetical protein	A5LH53	Enterobacteria_phage	4.0e-11	29.1
WP_078605230.1|889909_890977_-	hypothetical protein	NA	NA	NA	NA
WP_030182092.1|892046_892841_+|protease	serine protease	G9E4F4	Emiliania_huxleyi_virus	1.5e-09	26.2

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP023688|1784689:1790986|DBSCAN-SWA
CATGGGCGTCAGCCTCAGCAAGGGCCAGAACGTCGTCCTCAACCAGGACGGCACTCCCCTCGCGGACGTCACCGTCGGCCTGGGCTGGGACGCCCGGCCCGCCGGCGGCGCGGACTTCGACCTGGACGCCTCGGCGGTCGTCTGCGGCCCCGACCAGCGTGTCCTGTCCGACGCGCACTTCGTCTTCTACAACAACCTGACCAGCCCGGACGGCGCGGTCCGGCACACCGGCGACAACCTCACCGGCGAGGGCGACGGCGACGACGAGCAGATCCTGGTCGACCTGGACCGCCTCGGCGAGCAGACCGGCCAGGTCGTCTTCACCGTCTCCATCCACGATGCCGAGGCGCGCGGGCAGAATTTCGGCCAGGTCGAGGACGCGTACATCCGCGTCGTGGACAACCTGACGGGCCGTGAGATGTGCCGCTACGAGCTGTCGTACGACGCCGCCGGCGAGACGGCGATGGTCTTCGGGGCGCTCTACCGGCGCGGCGGCGAGTGGAAGTTCCGCGCCATCGGCCAGGGTTACGCGACCGGGCTGGCCGGTATCGCCACCGACTACGGCGTCAACGTCGGCTGATACCGGTACGCGAAAGGGCGCGCCCGGGAAGGGCGCGCCCCCGGGGCCCCGCCTACAGGTGCGAGGCGATGGCCGGCATCAGGTCCTGGAAGGTGCGGCCGGCCGCGGGCTCGCCGATGGCGGCCATCTCCCAGCCGCCGCCGGCCCGGCGTACCTTCGCCATGATCTGCGCGGTGTACTGGCCGCCGCCGGTGAGGGTGTAGCGGGCCAGCTCCTGGCCGGTGCTCTCGTCGACCAGGCGGCAGAACGCGTTCTGCACCTCGGCGAAGGTCTGCCCGGTGAAGGAGTTCACCGTGAAGACGATCTGGTCGATATGGGCGGGCACCCGCTGGAGATCGACGTAGATCACCTCGTCGTCGCCGCCCTGTCCCGCGCCGCCCACCAGGTTGTCCCCGGTGTGCCGCACGGAGCCGTCGTCGCTGATCAGGTGCTGGAAGAAGACGACGTCGACGGGCTCCTGACCGGCGAACAGCACGGCGGAGGCGTCCAGGTCGATCTCGCGGGCCATCAGCTTGGCGAGGAAGCCCTTGCGGGCGGCGGCCTGCCAGCCCAGGCCCATGCGGACCACGCTGAGTTCGCCCCCGCCGGACTTGCTCAGACTGATCTTCTGACCCTTGTCCAGGTTCACGGTCATGTGCTGTCACTCCTGCGTCGGGATGGCATGCCCCGGGCAGAGCGGCGGCCGCCGCCACCGGCCGGGAATCGCAAATCTACAGCACTGTAGAGGTAATGACGAAGTAAAGAAGCAGGGCCGCGGGGTGGAAACCGGACGGACGCCGCCCGACCGGACACTTGGCGGGCCCCGCCGGAATACTCACAGCGGGGCCCAGTCGTACGGTACCCAGCCGGGCGCGCGCACAACAGACCGCGTCGGCGGCTTTCCCGGTATCAGGCCACCCGCTCCGCCGGCCCCTCCGCCCGGCGCGCCTGAGGCTCCGCCGACCACTGCGCCAGCCGCCGCAGCGCCAGCGCCGAAGCGGACCCGGGCTCGGCGTGGTAGGTGACCAGCTGCTGGTCCGGATCGGCCGGCAGGGCGAGCGTCTCGTACGCCAGCGACAGGCTTCCCACCAGCGGGTGCGTCAGCCGCTTGCGGCCGAACCCCTTGTCCTGGACGTCGTGGGCCGCCCAGATCCGCCGGAAGTCCGCGCTCTTCGCGGACAGCTCATCGACCAGCGCGCACAGCTTCGGGTCGTCCGGGAACCGGCCGACGTCGCCGCGCAGCTGGGCCACGACGTGCGCCGCCTTGCCCTCCCAGTCGGCGTACAGCTCGCGCGTCGCCGGAGCGAGGAAGAGCTGCCAGGCCATGTTGCGCTCCTCGGCGGGCATCGCGGCGAAGTCGCCGAGGAGCGCGCGGGCCAGCCGGTTCCAGCCGAGGATGTCCAGCCGCCGGCCGATCACGTACGCGGGGACACCGTCCATCGCGTCGATCAGGTCCTGCAAGGCCGGACGCATCCGCTGCGGCCGGGGCGCCGGGCGGCGCCGCCGGGAGACCGGCCTGGCCAGATGGCTCAGGTGGGAGCGCTCGGCCCGGGTCAGCCGCAGCACGTCCGAGATCGAGTCCAGCACGGCCGCGGAGACGTTCTGCCCCCGCCCCTGTTCGAGCCGTATGTAATACGCCACGCTGACCCCCGCCAGCTGCGCCAGTTCCTCCCGCCGCAGGCCGGGTACCCTGCGCCGCCCGCCGTGAGGGGCGAGACCGACATCCTCGGGCTGGAGCCTGGCGCGGCGGGAGCGGAGGAATTCGCTCAGTTCGGTGCGCTGGTCCATCCCTGAATTATGACGGGCGCCGTCCGCGGTACGGCCAGGGTGGTTCTCGCAGTGGTACGACCGGCGAGCGTAGGTTCAGCAGGGCACTGGTTGCCCCGGGCACGCAACCCCACCCTGGAGAGCATGAACCGCACCTCTGTACCCGCATACGCAGCACCCGCCCCGAAGGCTCCGCTGGAGCGCACCACCATCGAGCGCCGGGAGCTGGGCGCGCACGACATCCTCATCGACATCAAGTTCGCGGGCATCTGCCACTCCGACATCCACACCGTGCGGGCGGAGTGGGGCGACGGCGGGAACTTCCCCATCGTCCCCGGCCACGAGATCGCCGGCGTGGTCAGCGAGGTCGGCCCCGAGGTCACCCGGTACGCGGTCGGCGACCGGGTCGGCGTCGGCTGCTTCGTCGACTCCTGCCGCGAGTGCGAGAACTGCCGGGCCGGCCTCCAGCAGTACTGCACCGGCGAGCTGGGCCAGGTCGGCACGTACAACGCCATCGGCCGGGACGGCCTGGCCACCCAGGGCGGCTACTCCACCCACCTCGTCATCGACGAGAACTACGCCCTGCGCATCCCGGACAGCCTGCCGCTCGACGCCGCCGCGCCGCTGCTGTGCGCCGGCATCACCCTCTACTCGCCGCTGGCGCACTGGAAGGCCGGCCCCGGCAAGAAGGTCGCCGTCGTGGGCATCGGCGGCCTCGGCCACATGGGCGTCAAGATCGCGCACGCGATGGGCGCGGAGGTCACCGTACTGAGCCAGTCGCTGCGCAAGAAGGACGACGGCCTGCGGCTCGGCGCCGACCACTACTACGCCACGTCCGACCCGGCGACCTTCGAGGAGCTGGCGAGCAGCTTCGACCTGATCGTCAACACCGTCTCCGCGCAGCTCGACCTGAACGCCTACCTGGGCCTGCTGCGCACCGACGGCACCCTCGTCCAGCTCGGCGCGCCGGAGCACCCGCTGCCGATCGCCCCGTTCGCCCTGATCGGCAACCGCCGCTCGCTGGCCGGTTCGCTGATCGGCGGCCTCCAGGAGACCCAGGAGATGCTGGACTTCTGCGGTGAGCACGGGCTGACCTCGGAGATCGAGGTGATCTCCGCCGACCGGATCAACGAGGCGTACGAGCGGGTGCTCGCCAGCGACGTCCGCTACCGCTTCGTGATCGACACCGCGACGATCTGACGGCCGGGCCCGCGCCCCGGGTGCCGCCACACGGCCGACACCCGGGGGTCACGGTCGGTACCGGTACGATCACCGATCGCGTGCTACGGTCGCTCCAGTTGCAGTTTTGGTACCCATGAACGTCATGTGCGCCTGACGGGATGTGTCCGTCGGGCGCCTTCTGTTTCTGCCGGTCACATCCGGATGGGCTCAATTGCGGCGACCCTGGAGACCGCGCCGTGCGGAATCCTCAACTGCCTCGATCGAAGGATAGGGACATGGCAACCGGCACCGTGAAGTGGTTCAACTCCGAAAAGGGCTTCGGCTTCATCGAGCAGGACGGCGGCGGCGCCGACGTCTTCGCGCACTACTCCAACATCCAGGCCCAGGGCTTCCGTGAGCTGCAGGAAGGCCAGAAGGTCAGCTTCGATGTCACGCAGGGCCACAAGGGCCCGCAGGCGGAGAACATCGTCCTCGCCTGAGCCGCCCGGCTTCGGACGGCGGAGCGACAACACGGCACGAGCCGGAACGCCCGAACGGGTGGCGTTCCGGCTCGTGCCGGTTCGGGGCCGGACATGCCCGATGCCGCCGCTTATCCCGCCGTCATTCCCCGCTCCGCCTCCCGCAGCGCCTCCGCGAGGATGCGCGCTCCCGTCTCCGCCTCCTCGACCGTCAGCGACAGCGGTGGCGCGATGCGCAGGGCGGAGCCCGACAGGCCGCCCTTGCCGATCAGCAGGCCGCGCTCGCGGGCGGCCTCCACGACGAGGCCCGCCGCCCGCGGCGACGGCTCGTCCGTGCCGGGCGCGACCAGCTCGACGCCGATCATCAGGCCGCGTCCGCGCACTTCCCGTACGACCCGCAGCCCCGCGCAGGCCGCCCGCAGCCGCTCGATGAGCAGGCCGCCGACGCGCCGGGCGTTGCCCTGGAGGTCGTGGGCCAGGAGGTGGTCGAGGTTGGCCAGGGCCGCCGCCATGGTGACCGGGCTGCCGCCGAAGGTGGAGATGGAGTTGGCGCCCAGGCAGTTCATCACCTCGGCGCGGGCGACGACGCCGCCGACGGACATGCCGTTGCCGATCCCCTTGGCGAAGGTGAGCAGGTCCGGCGGCCCGTTGCCGGCGTGCGCCTGCCAGCCCCAGAAGTGGTCGCCGGTCCGGCCCCAGCCGGTCTGCACCTCGTCCGCGATCCACAGGATGCCGTGCCGGTCGAGCACCTCGCGGAAGGCCGCGTACAGCCCGTCGGGCGGTGAGGTGAAGCCGCCGACGCCCTGCACCGGCTCGGCGATCAGCGCCGCGACGCCCGCCGTCTGGCCGAGCAGGTCCTCCAGGTCGGCGACGCAGGCGTCGATGTACGCGGCGTCGGACAGCCCCGCGTACGGGCCGCGGGTGCGCACACCTCCGTGTACGTACAGCGTCTGGAGCGGGGACAGGCCGGTCGGCGACCAGCCGGCGTTGCCCGTGACGCCGATGGCCGAGAAGGACCGGCCGTGGTAGCTGTTGCGCATCGCCAGGATCTGGTTGGAGCGCCGGTACACCGTCGCCAGCAGGAGCGCGGTGTCGTTGGCCTCCGTACCGGACGTGGTGAAGAAGACCCGGGCGTCCGGGATGCCGGAGAGCGCGGCGATCCGCTCCGCCAGGTCCACCATCGGGCGGGACAGGTAGAGCGTCGAGGTGTGCAGGATGCGGCCCGCCTGCTCGGCGACCGCCTTGGCGACCTCGGGCAGCGCGTGGGCGGTCATGGTGGTGAGGATGCCGCCGAAGAAGTCCAGGTAGCGGTTGCCGTCCGCGTCCCAGACGTGGCGTCCCTCGCCGTGCGTCAGCTCGATGGGCCGCTCGTACAGCAGCGTGAGCCAGTCGGGCAGCACGGCGCGGTGCCGGGCGTGCAGGCCGGTGGGGGCCGGCCCGGTGTCCGGTTGAGCGCCCGGTCCGGCCTCCGGGGCCCTCACGGCCGGACCAGCCCCTCGTACGCGTCGGGCCGGCGGTCCCGGTAGAAGGCCCACTGCTGCCGCACCTCGTCGATGAGGCCGAAGTCCAGGTCGCGGACGACCAGCTCCTCCTTGGTGTCGCTGGCGACCTCGCCGACGAACTGCCCGCGCGGATCGACGAAGTAGCTCGTCCCGTAGAAGTCGTTGTCGCCGTACTCCTCGACGCCGACGCGGTTGATCGCGGCGACGAAGTACTCGTTGGCGACCGCGGCGGCGGGCTGTTCCAGCTGCCACAGGTAGGCGGACAGGCCGCGGGAGGTGGCGGACGGGTTGTAGACGAGCTGGGCGCCGTTCAGGCCCAGCTGGCGCCAGCCCTCGGGGAAGTGGCGGTCGTAGCAGATGTAGACGCCGATCCGGCCCACGGCGGTCTCGAAGACCGGCCAGCCCAGGTTGCCCGGCTTGAAGTAGTACTTCTCCCAGAAGCCCTTGACCTGCGGGATGTGGTGCTTGCGGTAGGTGCCGAGCACGGTGCCGTCGGCGTCGATGACGGCCGCGGTGTTGTAGTAGAAGCCGGACTGCTCGACCTCGAAGACCGGCACCACGATCACCATGCCGGTCTCCCGGGCCAGTTCCTGCATCCGGCGGGTGGTGGGGCCGTCCGGTACCGGCTCGGCCCAGCGGTAGTGCTCCGGCTCCTGGACCTGGCAGAAGTACGGGGCGTTGAAGACCTCTTGGAAGCCGATCACCTGCGCGCCCTGCGCGGCCGCCGCCCTGGCGTGTTCCTCGTGCTTCGCGATCATCGATTCGGTGTCGCCGGTCCAGGACGCCTGAACCAGTGCGGCGCGTACGACGTTACGGACAACATCGGCCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP023688|1784689:1790986|1788471_1788675_+|WP_003981986.1|DBSCAN-SWA
MATGTVKWFNSEKGFGFIEQDGGGADVFAHYSNIQAQGFRELQEGQKVSFDVTQGHKGPQAENIVLA
>NZ_CP023688|1784689:1790986|1787158_1788214_+|WP_003981985.1|DBSCAN-SWA
MNRTSVPAYAAPAPKAPLERTTIERRELGAHDILIDIKFAGICHSDIHTVRAEWGDGGNFPIVPGHEIAGVVSEVGPEVTRYAVGDRVGVGCFVDSCRECENCRAGLQQYCTGELGQVGTYNAIGRDGLATQGGYSTHLVIDENYALRIPDSLPLDAAAPLLCAGITLYSPLAHWKAGPGKKVAVVGIGGLGHMGVKIAHAMGAEVTVLSQSLRKKDDGLRLGADHYYATSDPATFEELASSFDLIVNTVSAQLDLNAYLGLLRTDGTLVQLGAPEHPLPIAPFALIGNRRSLAGSLIGGLQETQEMLDFCGEHGLTSEIEVISADRINEAYERVLASDVRYRFVIDTATI
>NZ_CP023688|1784689:1790986|1786156_1787035_-|WP_003981984.1|DBSCAN-SWA
MDQRTELSEFLRSRRARLQPEDVGLAPHGGRRRVPGLRREELAQLAGVSVAYYIRLEQGRGQNVSAAVLDSISDVLRLTRAERSHLSHLARPVSRRRRPAPRPQRMRPALQDLIDAMDGVPAYVIGRRLDILGWNRLARALLGDFAAMPAEERNMAWQLFLAPATRELYADWEGKAAHVVAQLRGDVGRFPDDPKLCALVDELSAKSADFRRIWAAHDVQDKGFGRKRLTHPLVGSLSLAYETLALPADPDQQLVTYHAEPGSASALALRRLAQWSAEPQARRAEGPAERVA
>NZ_CP023688|1784689:1790986|1788785_1790135_-|WP_003981987.1|DBSCAN-SWA
MRAPEAGPGAQPDTGPAPTGLHARHRAVLPDWLTLLYERPIELTHGEGRHVWDADGNRYLDFFGGILTTMTAHALPEVAKAVAEQAGRILHTSTLYLSRPMVDLAERIAALSGIPDARVFFTTSGTEANDTALLLATVYRRSNQILAMRNSYHGRSFSAIGVTGNAGWSPTGLSPLQTLYVHGGVRTRGPYAGLSDAAYIDACVADLEDLLGQTAGVAALIAEPVQGVGGFTSPPDGLYAAFREVLDRHGILWIADEVQTGWGRTGDHFWGWQAHAGNGPPDLLTFAKGIGNGMSVGGVVARAEVMNCLGANSISTFGGSPVTMAAALANLDHLLAHDLQGNARRVGGLLIERLRAACAGLRVVREVRGRGLMIGVELVAPGTDEPSPRAAGLVVEAARERGLLIGKGGLSGSALRIAPPLSLTVEEAETGARILAEALREAERGMTAG
>NZ_CP023688|1784689:1790986|1785320_1785902_-|WP_003981983.1|DBSCAN-SWA
MTVNLDKGQKISLSKSGGGELSVVRMGLGWQAAARKGFLAKLMAREIDLDASAVLFAGQEPVDVVFFQHLISDDGSVRHTGDNLVGGAGQGGDDEVIYVDLQRVPAHIDQIVFTVNSFTGQTFAEVQNAFCRLVDESTGQELARYTLTGGGQYTAQIMAKVRRAGGGWEMAAIGEPAAGRTFQDLMPAIASHL
>NZ_CP023688|1784689:1790986|1784689_1785268_+|WP_003981982.1|DBSCAN-SWA
MGVSLSKGQNVVLNQDGTPLADVTVGLGWDARPAGGADFDLDASAVVCGPDQRVLSDAHFVFYNNLTSPDGAVRHTGDNLTGEGDGDDEQILVDLDRLGEQTGQVVFTVSIHDAEARGQNFGQVEDAYIRVVDNLTGREMCRYELSYDAAGETAMVFGALYRRGGEWKFRAIGQGYATGLAGIATDYGVNVG
>NZ_CP023688|1784689:1790986|1790131_1790986_-|WP_003981988.1|DBSCAN-SWA
MADVVRNVVRAALVQASWTGDTESMIAKHEEHARAAAAQGAQVIGFQEVFNAPYFCQVQEPEHYRWAEPVPDGPTTRRMQELARETGMVIVVPVFEVEQSGFYYNTAAVIDADGTVLGTYRKHHIPQVKGFWEKYYFKPGNLGWPVFETAVGRIGVYICYDRHFPEGWRQLGLNGAQLVYNPSATSRGLSAYLWQLEQPAAAVANEYFVAAINRVGVEEYGDNDFYGTSYFVDPRGQFVGEVASDTKEELVVRDLDFGLIDEVRQQWAFYRDRRPDAYEGLVRP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003981982.1|1784689_1785268_+	TerD family protein	K4JRX3	Caulobacter_phage	3.5e-32	40.1
WP_003981983.1|1785320_1785902_-	TerD family protein	W8EDB4	Pseudomonas_phage	9.7e-06	28.7
WP_003981984.1|1786156_1787035_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003981985.1|1787158_1788214_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	5.2e-66	39.8
WP_003981986.1|1788471_1788675_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	8.0e-16	59.4
WP_003981987.1|1788785_1790135_-	aspartate aminotransferase family protein	A0A2D1G879	Mycobacterium_phage	3.0e-05	29.9
WP_003981988.1|1790131_1790986_-	hydrolase	M1H5W0	Paramecium_bursaria_Chlorella_virus	2.4e-45	38.3

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP023688|5397718:5403196|DBSCAN-SWA
AGTGAGCGCCTCCAAGAAGAAGGGCACCAGCGCCGAGAGCGCCGTCGTCGCCTACCTGCGCAGCCGCGGCTTCATCCAGGCCGAGCGCCGCGCTCTGAACGGCAGTCAGGACCGCGGCGACGTCGCCGGCATCCCCGGCACCGTCCTGGAAGTCAAGAACTGCGCCCGCACCGAACTCGCCTCCTGGGTCGACGAGGCCGAGATCGAACGAGTCAACGACGGTGCATCTCTTGGGGCCGTGTGGAGCAAGCGCCGCGGCAAGAGCAATCCCGCTGACTGGTTCGTCATCATGAGCGGCCGGCAGTTCGTATCGATGCTGCGCGAACTCCTCGAACTTCCTCCGCAGGCAGATGAGCCCAAGGAGGGGGAAGCGGCATGACGAAGCCACTGGCAGAACGCTTCTGGTCCAAGGTGCGGGTGGCCAACACGCTGCACGACTGCTGGTCATGGCTCGGCGCCTGCACCCCCACCGGCTACGGCAACGTGTACGACGGTGCACGAACCGAGAAGGCGCACCGGGTCGCCTACATGCTGACCTTCGGGAAGATCCCGAACGGTTACGAGATCGACCACCTCTGTCACAGGCGTGGCTGCGTCAATCCCTGGCACCTGAGGGCGATCGCGCATGCCGAAAACCTGCGCTCCAGTCGGCCGGCGACGGCCACGCATTGCCCTCACGGCCACGCCTACACCGGCCATCGCCAGCGGAATGGGCGGCGCGAGTGCCACGTCTGTCGCAAAATTCGAGAATCGCGACGCGTGCGTCACTCCCACCAAGGAGCCGCCGCATGATCGCCACCGGCAACGACGCCACCGGCCAGGCCCTCGCCGCCCGCGTCGCCGACCTCATCACCGACGCCGCCAACAACAGCCCCCGCTCCCGGCAGACCCGCATCGGTCCCTCCGAGGTCGGCGAGCCGTGCGAGCGCAAGCTCACCTACAAGCTCTTCGAGTGGCCGGCCTGCAACACCGACCACGACCCCATAGCCAGCGTGATCGGAACTGGTTTCCACGGATGGATGGAAGAGGTCTTCACCGGCCGCAACGCCGTACTGCCGGATGGGCGCCCGCGCTACCGGATCGAAGAGCGGGTAACCGTCCGCGAAGGCGGCAGTACCGTCCTCGGATTCGATGTCACGGGGTCCGCCGACCTGTACGACCGGCTGACCCGGACCAACCTCGACTGGAAGCTCGTGGGCGTCTCCAGCTTCGACGCGTACCGGCGTAAAGGTCCCGGGGTGCAATATCGCGTACAAGCGCACCTCTACGGCCTCGGCCAGGAGAACGCCGGAGAATCGCCGGAGCGAGTAGCCATCGTCTTCGTGGCCCGCCACCACGAACTGCGCGTCCACGTCTGGACCGAGGAGTACCAGCGTCAGGTGGCGCTCGACGCCCTGGAGCGGCTCGACCGCATCAAGGCGCGCCTGCTGGCGCTGGACCCCGAAGCCAATCCGGAGCGCTGGTCGGAAATCCCCATACCGGAAGACGCCAAATGCAAGTGGTGCCCGTGGTTCCGGCCCGGTTCCAGTGACCTGAGTTCCGGGTGCCCCGGTGTCATGAAGCAGGTCAGGCGGCACGGCTTCGAGGAGCTGGTCGCGTGAAGACCACCGAGGAGCGCTTCTGGGAAAAGGTCGACGGAGCAAACGTGGCCGGTTGCTGGATCTGGCGGGGCGCCGGCAATGGCTACGGCAGGTTCTACGCCTCGGGCCGCAACGTACTAGCGCACCGATGGGCATACGAATATCTCCGAGCTTCGATCCCGGAATCGCTTGTCCTTGACCATCTCTGCCGCAATGCCCAGTGCGTGAATCCGTGGCACCTAGAACCGGTCAGTCAGGCGGAGAACCTCCGTCGTGGGAACGGGTTCAGCGGACGTAACGCGCGCAAAACGCACTGCCCCCGGGGGCATCCGCTGACGGGCATGAACAGCTATCTCGCCCCTTCGGGTGGGCGAGCTTGCCGCACCTGCCGCCGTTCGGCGTATCGAGCCCACCGCGCCGCTAATCGCGAACGCATCAACACCCGGAAACGAGCGGCTTACGCCGCCCAAAAGCTCGCCGACTCGCAGAAGTCGGCGTGATCAATCCCACCTCCCCCAAGGAGCAAAGGAACTCATGAGCACTCCCGCTATGGACGCGAACTCCTTCCTGATGGCGGGCGGCGCCAAGTCCGCCCGGTTCGAGCAGCCCGGCGCCTCCGTCACCGGCCGCATCAGCGAACAGCCCGTCGTGCAGCAGCAGAAGGATTTTTCCACCGGCGAGCCGCTGTTCTGGAACGACGGCCAGCCGCGCATGCAGCTGTCGGTGACGCTGGCCACCGACCAGCGCGACCCGGCCGACGCCGACGACGACGGCGCGCGCCGCATCTACGTCAAGGGCCAGATGAAGCAGGCGATCCAGCAGGCCGTGCGGGCCTCCGGCGCCCGCGGCCTGGAGGTCGGCGGCGTCCTGAAGGTCACCTACGTGCGCAACGGCACCGCGAGCAACCCGCGGTTCAACCCGCCCAAGGAGTACGCCGCCGAGTACACCCCGGCTGCACAGGCCGAGCTGAACACCCCCGAGCCCGCGGCCCCGGCCGGAGTCAATACCACCACCGGCGAGATCACCACCCCGGCCGCGTCCGCGGCGCCGGGCCAGCCGGACCTGAACGACCCGGCCGTCCAGGCGCTGCTCGCCCAGCTCCAGGGCCAGCAGCGGCAGGCCGCGCCTGCGGCGAACGGCGGCAGCACCGAGCCCCCGCCGTTCTGAGCCGCGCCACCGCACCACCTCGCCCGCCCGGTAACCAGGCCGGCGCCCCGGGTCCGACGCCCGGGGCGGGCACCGAGGCCGCCGCCTTCGCGTACCACCGGACAAGGAGCACCGCCTTGAGCACCGAGCCACCGCAGGACACCCTCCGTGCCGCGCTCGCCTGGCACGCCGCCGGCGCCAGCGTCGTCCGCGTGGCCACCGACGGCACCAAGCGGCCGCTCGGCAACTGGGCAGCACACCAGAAGGAACGTGCCACCGAGCAGCAGCTGCGCGCCTGGTTCGCAGGCGGCCACCCCGGGCTCGGCATCGTGTGCGGCGCCGTCTCCGGCGGCCTGGAGATGCTGGAGTTCGAAGGCCGCGCCGTCGCCGAAGGCGTCCTGAAGGAGTTCGGCGAGATCGCCGAGGACTCCGGGCTCGGCGGCATCTGGAAGCGGGTGGCCGCCGGCTACCTGGAGCGCTCCCCGTCCGGCGGCATCCACGTCCTGTACCGCCTGGACGGGCAGCCGGTGCCGGGCAACACCAAGCTGGCCCGCCGCCCGGCCCGCGACGACGAGCTGACCGACGATGAGCGGCAGGTGCTCGCGAACAAGCCCGGCAAGGTCTTCGTGCGCGATCTTGTCGAGACCCGCGGCGAGGGCGGCTTCGTCGTCGTCGCCCCCTCCGCCGGGCCCGTGCACGAGACCGGCCTGCCCTACCAGCTGCTCGCTGGCGCACCGGAGACGCTCGCCGTCGTCACGGCCGAGGAGCGCGAGGCGCTGCACAGCGTCGCCCGCACCCTCGACACCATGCCCGCCGCCACCTTCCCCGCCCCGGCGGACCCGGCACAGGAGGCGTTCTTCCGCGCCGCCGCCCCGGCGGCGGACGGCTCTCTGAAGCCCGGCGAGGACTTCGAGCAGCGCACCGACTGGACCGACATCCTCACCCCGCACGGCTGGCGCCTGCTCGGGCAGCGGGGCCGCACCCGCTACTGGCAGCGGCCCGGCAAGAACGGCCTGGGCATCTCCGCCACCACTGGCCACGCCGACGACCGCGACCGCCTCTTCGTCTTCTCCTCCAGCACCGAGTTCGACCCCGAGCACCCCTACACCAAGTTCGCCGCCCACGCCCTGCTCGAACACCGCGGCGACTACAGCGGCGCCGCCAAGGAACTGCGCCGCCGCGGCTACGGCACCGCGCCCGAGCGCCACCTGCGGACCGTCCCGCCGCCGACCGCGCCGGTAGCGGGCGAGCGGCCGGCGACTGAAGGGTCCGCCGCCTTGAAGCGGCAGGCCGATGACGGCACCTGGACGGCGCCCGAGGAGCGCCGGCCGCTGCTGCCGGTGCCGATGCCGCGACGCGACTGGGATGACATCGGCAACGCGCAGAGGGTCGTGGACCGCTACGGCACCGAGATCCGCTGGATTACCGACACCGAACAGTGGGCCTTCTACGAGGCGGGCCGGTGGGTTCTCAAGGGCGCCAACACCGGCGTGTGGACCCGGGTCGTGTCCACCGTCGATCACCTGGCAGACGAGGCCGACAACTACTCCGACGAACCCCCGGCCATCGAGCCGGACGTGCGCCCCTCGAAGGACGACCTGCTGACCGAACGGGAGAAGTTCACCAAGTGGGCGCGGGGGCAGCGGATGCGGACCAAGCTGGCCGCGGCCCGGGAAGTCCTGCAGGCCCACCCGGCGGTGCACTGCACCATGAGCCACTTCGACCGGCCCGAGATGCTCCTGAACGTGGCCAACGGGATCGTCGACCTGAAAACCGGCGACCTGCTCGCGCACAGCCGGGATCTGTACCTGATGCAGCAGTCACCCGTCCGGTACGACCCCAAGGCCACCTGCCCGCAGTTCGAGGCGTTTCTCGACAGCGTCATGCCGGACCCGGAGCGACGCGCCTATCTGGCCCGGGTCGTCGGCTACACGATCACCGGTTCCACCGAGGAGCAGGTGATGTTCATCCACCACGGCGACGGCCAGAACGGCAAGGGCGTCTTCATGCGGGTGATGATGGAACTGCTCGGCGACTACGCGCAGTCCGTTCCCCGCTCGACGCTGCTGGCCAAGCAGTCCGACGGCATCCCCAATGACATCGCCCGGATGATGGGCAAGCGGCTGCTGTCGACCACCGAGACCAGCGCCGGCAAGAAGCTGGACGACGAGCTGGTCAAGCAGCTCACCGGCGAGGACACCATGTCCGCCCGGTTCATGCACGCCGAGTTCTTCGACTTCCGCCCCGTCGGGAAGATCCACCTGGCCACCAATTACCTGCCGCGCGTGGGCGGGGGGCACGGGATCGCCCGGCGCCTGCAGGACATCGGGTGGGACGTCGTCGTTCCGCCGAACAAGCGCATCGCCAAGCTCGACGAAAAGATCATGGCGACCGAGGCGGCCGGCGTCCTCAACTGGGCCATCCGTGGCTGCCTGGAGTGGCAGCGGGACGGGCTGTCCGTGCCCGAGGCGGTCCGGGAGAAGACGCGCGAACATCTCGCCAGCTCCGATCCGCTGGCCATATGGCTGGAGGAGGAGACCGCCGAAGTGCCGCAGGGCGCCACCGAGACCCGGCTGCTCTACGCCAACTACAAGATCTGGTCCGAAGCCTCGGGCCTGCGCCCCATGTCGGTCACAGCGTTCGCCCTGGCGCTCAAGGAGCGCGGCATCGAGAGCGGCAGGGACCCGAGGTCACGCCGGGCCCTGACGCTTGGTGTGCGTTTGTCCGGCATGACCTACTTGGAGGGTGTCTGA

Protein sequences of DBSCAN-SWA_3

>NZ_CP023688|5397718:5403196|5398505_5399318_+|WP_003979865.1|DBSCAN-SWA
MIATGNDATGQALAARVADLITDAANNSPRSRQTRIGPSEVGEPCERKLTYKLFEWPACNTDHDPIASVIGTGFHGWMEEVFTGRNAVLPDGRPRYRIEERVTVREGGSTVLGFDVTGSADLYDRLTRTNLDWKLVGVSSFDAYRRKGPGVQYRVQAHLYGLGQENAGESPERVAIVFVARHHELRVHVWTEEYQRQVALDALERLDRIKARLLALDPEANPERWSEIPIPEDAKCKWCPWFRPGSSDLSSGCPGVMKQVRRHGFEELVA
>NZ_CP023688|5397718:5403196|5398092_5398509_+|WP_003979866.1|DBSCAN-SWA
MTKPLAERFWSKVRVANTLHDCWSWLGACTPTGYGNVYDGARTEKAHRVAYMLTFGKIPNGYEIDHLCHRRGCVNPWHLRAIAHAENLRSSRPATATHCPHGHAYTGHRQRNGRRECHVCRKIRESRRVRHSHQGAAA
>NZ_CP023688|5397718:5403196|5399831_5400464_+|WP_030184075.1|DBSCAN-SWA
MSTPAMDANSFLMAGGAKSARFEQPGASVTGRISEQPVVQQQKDFSTGEPLFWNDGQPRMQLSVTLATDQRDPADADDDGARRIYVKGQMKQAIQQAVRASGARGLEVGGVLKVTYVRNGTASNPRFNPPKEYAAEYTPAAQAELNTPEPAAPAGVNTTTGEITTPAASAAPGQPDLNDPAVQALLAQLQGQQRQAAPAANGGSTEPPPF
>NZ_CP023688|5397718:5403196|5399362_5399797_+|WP_003979864.1|DBSCAN-SWA
MAGCWIWRGAGNGYGRFYASGRNVLAHRWAYEYLRASIPESLVLDHLCRNAQCVNPWHLEPVSQAENLRRGNGFSGRNARKTHCPRGHPLTGMNSYLAPSGGRACRTCRRSAYRAHRAANRERINTRKRAAYAAQKLADSQKSA
>NZ_CP023688|5397718:5403196|5400580_5403196_+|WP_003979862.1|DBSCAN-SWA
MSTEPPQDTLRAALAWHAAGASVVRVATDGTKRPLGNWAAHQKERATEQQLRAWFAGGHPGLGIVCGAVSGGLEMLEFEGRAVAEGVLKEFGEIAEDSGLGGIWKRVAAGYLERSPSGGIHVLYRLDGQPVPGNTKLARRPARDDELTDDERQVLANKPGKVFVRDLVETRGEGGFVVVAPSAGPVHETGLPYQLLAGAPETLAVVTAEEREALHSVARTLDTMPAATFPAPADPAQEAFFRAAAPAADGSLKPGEDFEQRTDWTDILTPHGWRLLGQRGRTRYWQRPGKNGLGISATTGHADDRDRLFVFSSSTEFDPEHPYTKFAAHALLEHRGDYSGAAKELRRRGYGTAPERHLRTVPPPTAPVAGERPATEGSAALKRQADDGTWTAPEERRPLLPVPMPRRDWDDIGNAQRVVDRYGTEIRWITDTEQWAFYEAGRWVLKGANTGVWTRVVSTVDHLADEADNYSDEPPAIEPDVRPSKDDLLTEREKFTKWARGQRMRTKLAAAREVLQAHPAVHCTMSHFDRPEMLLNVANGIVDLKTGDLLAHSRDLYLMQQSPVRYDPKATCPQFEAFLDSVMPDPERRAYLARVVGYTITGSTEEQVMFIHHGDGQNGKGVFMRVMMELLGDYAQSVPRSTLLAKQSDGIPNDIARMMGKRLLSTTETSAGKKLDDELVKQLTGEDTMSARFMHAEFFDFRPVGKIHLATNYLPRVGGGHGIARRLQDIGWDVVVPPNKRIAKLDEKIMATEAAGVLNWAIRGCLEWQRDGLSVPEAVREKTREHLASSDPLAIWLEEETAEVPQGATETRLLYANYKIWSEASGLRPMSVTAFALALKERGIESGRDPRSRRALTLGVRLSGMTYLEGV
>NZ_CP023688|5397718:5403196|5397718_5398096_+|WP_003979867.1|DBSCAN-SWA
MSASKKKGTSAESAVVAYLRSRGFIQAERRALNGSQDRGDVAGIPGTVLEVKNCARTELASWVDEAEIERVNDGASLGAVWSKRRGKSNPADWFVIMSGRQFVSMLRELLELPPQADEPKEGEAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003979867.1|5397718_5398096_+	hypothetical protein	A0A1B0XUC9	Freshwater_phage	7.7e-12	38.5
WP_003979866.1|5398092_5398509_+	HNH endonuclease	A0A1J0MCC0	Streptomyces_phage	1.0e-20	46.0
WP_003979865.1|5398505_5399318_+	hypothetical protein	G9FHE5	Rhodococcus_phage	2.6e-41	37.7
WP_003979864.1|5399362_5399797_+	HNH endonuclease	A0A088FQF5	Mycobacterium_phage	5.2e-28	49.3
WP_030184075.1|5399831_5400464_+	hypothetical protein	A0A1D8EQ72	Mycobacterium_phage	1.1e-31	53.1
WP_003979862.1|5400580_5403196_+	phage/plasmid primase, P4 family protein	A0A0P0IX98	Lactobacillus_phage	3.7e-68	35.1

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP023688|5420283:5446024|DBSCAN-SWA
CGTGTGTGAGGAACCCGGCTGCGAGAAGCAGATCGACCGGGGGCTCGCGTACCTCTGCGGCGAGACGCCGGGCGACGACGAGTACGGCTGTGGCGGCTACTTCTGCGGCGAGCACCTGTACATGGCTCCCGAGGGGCAGCACGGAGAGCGCTGCATCCGGTGCCGCGACAACGGCGCCGACCCGCTGGAGAACTCGCCGGACGCGATGGTCGCCACGTTCGAGAGCGGCACGGCCGTAGGTGCTTGACATTTGAACTGCACCGAAGTCATGATCTGCTCAACTAGCATCACTGCGCTTTGAGGGCCGCCTGAGACCAGGCGGCCCTCACGCATACCCGAGGGGGTGCAGCATGCCCCCCAGGCTCGTCACCGCCGCCGACGCCGCCCACTACACCGGCCGGCCCGTCGGCACCATCTGGCGGTGGGCCAGCGAAGGCCGCATACGCCGCACCGGCCGAGGCAAGCAGGCCCGCTACTACCTGGACGACCTGCCCCGCGCCACCCGCGACGAATGGACCGGGCTCCTCACCCCCGGTGAAGCCCCGCCCCTCCCAGACGGGGCGCGCGCCGCCTGACCCCCGACCGGGCCCGACGTTCCCCCAAGACGGGCCCCGCCTGCTGCCCGGCACCACGGCGGCCCGCCGGGCAGCAGGCACCAATCCGATCACGACCGTTCCCCTCACGCGGCCCGTGCGTCACCATGGCGCCATCAACCGCGACTCATGGGGGACCAGTGTTCGGCTCGAAGAAGACCGACGAAGAGAAGGCCGCCGCGAAGGCCCTGCTGGAGCTACGGCTCGCGGCCTCCGCTATCGGCGGCCTGATGGTCCGCAAGGACCCGCTGCGCTTCACCGCGCCAGGACAGATGGACGTCCCCGTCGGGGGCGCCAAGGTCACCGTGGACCGGGGAGAAGCCGCCAAGCGCATCACAGCCACGCGCGTGGCCCTCACTGGGATCTTCGCTCTGGCGTTGAAGAAGGACAGCACCAAGCTGTTCGTGACCATCGAGGGTGCCGACGGCTCGGCCATGCTGCTGGAGTGCCCGGCCAAGAAGGAAGCGGCTGCACGGAAGTTCGCCATCCTCGTACACGCCAAGCACCCTGCATAGCCCCCGACCCCGGGAGGGGAGGCCCCTATGCCCCCCTACGCTCCCCCCTCCCGGTGCACGGACCCCCAGTGCCACGAGCTGGCCACGCAGCGAGGCAGGTGCGACGAGCATCAGCCCATCGCATGGTCAGGCAGGGATGACAAGCAGGCCCGCTACGGCATCAGCTCGGGCACGTGGCGCAAGCTCAAGCGACGTGTTGATCAGCGTGACCATGGCTGCTGCTACTTGTGCGGGGCCGAGCAGCCCGACGACCCCGAAGAGCCACGCCACGTGCTCGATCACATCACGCCGATTGCCGAGGGCGGCTCGGTGACCTCGCTGGACAACCTCGGGCTGCTCTGCGGGTCGTGCGATGCGATCAAGAGCCGCGCTGAGGCCATCCGAGGCGCCCAGCGGGCTCGCCGGCGCGCCAAGAGATCATCATGAGGCTTCCGACGGGCCTCGCAGGGCAAACGCCAGGCCGATTCCGAGTCTTTCAGGTCCCTGACCTGCGCTTTCGTCGATTCCGGAAGCTTGGCGAGCCGCCCGAGGAGCTAGAGGGGGCTTCTGACCTGCGGTTTCGACCAGAATGCGGGCTGCGGCGAGACGAAAGCGCGCGCCCAAGTGCACGATTTCGGGCCGAGATGCGCCCTTTGGAGTGTCCGAGCCATCCCTCTCGCCTAGCAACATCACCTACTGCCCGGGGGTAGGGGAGTCCGGATCACGACCAAGATCGCTTGGGGACCCGCCGCGGTTGCCTTTCCGTGCTCACGCTCACATGAGCAACGGGGGGTCTGCGCAGGTCAGAGCCTTGCAGGCCGCGTTTGTGCAGGTCAGAGCGCTGCGGGCGACCGGAGAGGGGTTGATCATGGCGAAGGCTGCTGCTCCCGCCGCCCTGAAGCTGATCACTGGCCGGTCTCCGGGCCGGGACTCGGGTGGCCGGAAGGTGGAGCCCGGCCCGGCGTTCAAGCGGGTGCCGCCGAAGCCGCCGACGTGGCTGTCACGGGAGGCGGCCGCGGAGTGGAAGCGGGTACTGCCGGAGCTGTCCCGCCTGGATCTGGTCAAGGAGCAGGACCGGGCGGCGCTGGTGGCGTACTGCGAGGCGTGGGCGACGTTCGTGTCGGCGACGCGGGTGGTGCAGGAGGAGGGGCTCGTCATCGAGGCGCGGCAGGGCAAGCTGGCGCATCCGTGCGTGGCGATCGCCCGGAATGCGGCCCGCGAGATGAGGTCGTGGGCGGCACACTTCGGCCTGACGCCGTCGACGGAGCAGGCCCTGGCTCGAGGCGAGGGCGGCGATGGCGACGAAGCGAACCCGTTCGCCGGCTCCGGCTGACCTGGGCATCTCTGCTGAGGTCGCGTGGTATCTGGAGTCCAGGGGGATCCCTCTGCCGGACTGTCCGCCGAAGGTGCAGACGCCGTCGCCCGGCGAGGCGCCGGGTGCGGTGTTCGATCCGGAGCGGGTGGACCGGGTGCTGCGCAGCTTCCATCTGCTGCGGCACACGCAGGGCAAGTGGGCCGGGAAGCCCTTGGACCCCGACCCGTGGCAGGTGGCCTACATCCTGGCGCCGGTGTTCGGCTGGGTGCGGTGGGACGACGAGGCCGAGGGCTACGTGCGGATCGTCCGCAAGCTGTACGTGGACGTGCCGCGACGCAACGGCAAGACGACGCTGTCCGGCGGCATCGCGGTGTACCTGATGGCCGCGGACGGCGAGCCGGGCGCGCAGGTGTATGCGGCGGCCACGTCGGAGAAGCAGGCGCGGTACACCTTCGATCCGATCAAGACGATCGCGGAGCGGGCGCCGGCGCTGAAGGGCAATGTCAAGGCGTACACCAAGAAGATCACGCACCCGGCGAGTGGCAGCTACTTCACGGTCGTCTCGTCGGTGGCCGAGGCCCTGCACGGTGCGAACGTCCACGGCGGGATCATCGACGAGCTGCACGTTCACAAGAGCCCGGACCTCGTCGAGACGATCGAGACAGGCACGGGCTCGCGCCGCCAGCCGCTGGTCGTCATCATCACGACGGCCGACGAGGGCAAGCAGGAGTCCATCTACGACCGGCGCCGCCAGTATGTCGAGCAGCTCGCCCGCGGGGCCCTGCACGACCCGGACACCTACGGCGTGGTGTGGGGCGCCGACGAGAGTGACGACCCGTTCGCCGTGGAGACGCAGCGCAAGGCGAATCCGGGCTACGGGGTCAGCCCGAGCGCGGCGTACCTGAAGGGCGCGGCGGCCGAGGCGCAGCAGTCGCCGGCCGATCTGGCCAAGTACCTGCGGCTGCATCTGGGCATCCGCACGAAGCAGAGCACCAGGTTCCTGCGTCTGGAGGACTGGGATGCGAACGCCGGGCTGGTCGACGAGGCGGCGCTGGCCGGGCGGGACGCCTACGGCGGACTGGACCTGGCCAGCACGTCCGACCTGTGTGCGCTGTGCTGGCTCTTCCCCGACGACGCCACCGGCACCCTGGATGCGGTCTTCCGCTTCTGGACCCCCGAAGACAACCTGCGAGCCCTGGACAAGCGCACTGCAGGCGCGGCCTCGCGCTGGGTCCGGGAGGGCTTCCTGGTCGCCACGCCCGGAAATGTGTGCGACTACGACTTCATCCGGGAGCAGGTCCGCCGCGACAGGGACGCGTTCAAGGTCCGGTCGATCGGCTACGACCCGTGGAACGCCTCGCAGTTGACCAATGACCTGGTGTCCGAGCGGGCGCCGATGGTCAAGGTCAGGCAGGGCTTCGCCACCATGTCGCCGGTGCTGAAAGAGATTCAGCGCCTCGTGCTGCAGGGGACGCCGGAGGCACCGGCGCTGCGGCACGGCGGACATCCGGTGACCCGCTGGTGCGTGGACAACCTGGCCGTGACCATGGACCCGGCGGGCAACGTGAAGCCGGACAAGGCGAACTCCGGCGACAAGATCGACGGTGTGTCGGCGCTGGCCACAGCGATGGCGGAGGTCGTGGCGCGGCCGCCGCGGCGCAAGAGCCGGTACGCGGACGAGGACGAAATCATGGTCGTGTAGCGGCCGGGACGGGGGCTGCTCATGTTCGCGTGGCGTCGCACGGCGGTCCGCAAGCGGGTCGTGGTCAATCTCGCCGACAAGGCGTTCAACGGCGTGTTGTGGGCCCAGCGCGGCCCGCTGCTGGTGCTGCGGGACGTACAGCTCCTCGAGGCCGGGCGGGCGCCGCAGCAGGTGGACGGCGAGGTCGTCATCGAGCGGGCGCGCGTGGAGTTCACGCAGGTCCTCGCGAGTACGGGCGGGGGTGGCTGATGGCGTTCGTCGTCTCCTCCGGCCAGCTGTCGGTGACGGGGGCCGGGGTGACGCCGGGGTATGCGGCGATGCCGCTGCCGGCCGCGCCGTGGGAGTACGCGGAGATCTGGCGCACCCAGCCGCAGGTCCGCACGGTGATCGGGTTCCTGGCGCGGAACGTTGCGCAGCTCGGGATCCATACCTTTCGAAGGATCAGCGACACGGACCGGCAGCGGCTGACCGACCACCCCCTGGCGCGGGTCCTCGCCGAGCCGCTGCCGCGCTTCACGCCGTACCGGTGGGTGGAACGGCTGGTGTCCGACCTCGCCTTGTACGACAACGCCTACCTGATCAAGCTGCGGCTCAACGGGACGCTGCGGCTGCTGCCGGTGCCACCGACACTGATCCGCCCGTACCGCGGGAACTGGATCGCCCCGGAGTACTACGAGACAGCAGGCGGCCGGGACTTCGCGGTCGAGGACGTGGTGCACATCCATGGCTACGCCCCCGAGAACTTGACCTACGGGTCTTCGCCGATCGAGTCACTGCGGGAGTTGCTGCTGGAGTCGTCGGAGTCGGCGGCGCAGCGGGCAGCGATGTGGCGCGGCGGCGCGCGTGTGACGGGTGTGCTGAAGCGGCCGATGGACGCGCCGGAGTGGAGCGCGAAGGAGAAGGCCCGCTTCCGGGAGATGTGGCGGTCCTTCACGCAAGGCGGCGGCGCCGAAGGCGGCACGCCGATCCTGGAGGACGGCATGGAGTACGTGCCGGTCGGCATGACCTCCGAGGCGGCGCAGTACATCGACGCCCGCAAGCTCACCCGCGAGGAAGTCTCGGCGGCGTACTACATCCCGCCGCCGCTGATCGGCATCCTCGATCACGCCACCTACAGCAACATCAAGGAGCAGCACGCGCACCTGTACCAGGACACGCTCGGCCCGTGGCTGGCGATGCTGGAGCAGGAGATCGCCGCACAGATCCTGCCGGACCTGCCGGGCGACAACGCCAGCGTGTACTGCGAGTTCAACATCGCCTCCAAACTCCGCGGCTCTTTCGAGGAGCAGGCGGTCGCCGCGTCGACTGCCACGGGCGGGCCGTGGATGACCCGCAACGAGATCCGGGCCCGCAACAACCTGCCGGCCGTCGAGGGCGGCGACGAGCTGATCGTGCCGATGAACGTCACCGAGGGCGGCCTCGCCTCCCCGCGGGATACGGCGCCGGAGCCGGAGGCGCTCCCAAAAGCGCGCGGCCTGGCGCTGACGAAGTCGGCGGCCAGGCCCGATGACCTGGCCACCTTCGAGGAGGGCCGGGACGCACTGACGTCCGCCCTGGAACGGTGGACGCAGAGGGCGGCGGACAAGCTGCTGACGGCGGCCGGCGCCAAGGCGCAGGGCATGCCGGATCTGCTGGCGGTGTGGGCCGAGGGCCACGAGGACCGCCTCGCGCAGTTGTCGGCGCTGCTGGCTGAGCACGGGTACCGGCTGGCGCAGATCGGGGCCTGGGAGGTGCTGGACCGGTGGAACCCCGACGCGTCGGGCTGGACACCGGATGTGATGCTCGCCTGGATTCTGGCGGCTGCCGAGACGCACGCCGAGCAGCACGAGGAGGCCGGGCGCGAGGCGGTCGCCAAGGTCCAGGAGGAGGGCGGCGACAACTGGCCAAAGGCGCTGGCGGTCGCGGCGGCTGCGTGGGGGATCGCCGCCGCAGGGAGATCCCTGACCGCGGCCACCGAGCTGCGCAGCTTCGGCGGACACGATGCCGCATCCGCCTCGGGGCTGACACGCAAGGTGTGGCGGACGGGAGGCGCGACACCGCGCCCCTCGCACCGCGCGCTGGACGGGCAGAGCGTCGCCCTGGACGACGTGTTCGGCAACGGCTGCCGCTGGCCCGGCGACGGCACGGCGAAGGTCGGCGAGAAGGCGAACTGCCGGTGCCGCCTGGACTACGAGACGGGGTGAGCCGTGGCCATCACCGTCGTCGTCGGCCCGCCGTGCGCGGGCAAGTCGACCTGGATCAGCGAGCAGTGCCAGGCCGGGGATGTCGTCATCGACTTCGACAAGATCGCCCAGGCGCTGGGGTCGGAGCAGCCGCACGCGGCCCCCGAACCGGTCCGCGAAGTGGCCTTCGCCGCCCGCAAAGCCGGCATCAACCGCGTCCTGCGAGGCGTCGAGGCCGACGCGTGGATCATTCACACAAACCCGTGGCCAGGCCAGCTCGCCCGCTACGAGGATGCGGGAGCGCAGATCGTCGTCCTCGATCCGGGACTGGATGAGTGCCTGGCACGAGCCGCCGCAGACGACCGCCCCGAGGGCACCGAGGATGCCATCCGGCAGTGGTACGACCGCCCGCCGCTGGCCGACCTGGAGAAGAGGAGGGCAGCGGGTATGCGCACGAAGGACTTCGCCGCGAAGGTCAAGGCGGCCGGTCCCGTCGACGGTCTCGCCGAGGGCCAGTTCACCGCCCTGGTGTCGGTGTTCGGCAACGAGGACAGCATGGGGGACGTCGTCCGGCCGGGCGCGTTCACCGAGACGCTGGCGGCCTGGAATGAGAAGGGCGATCCGATCCCCGTCATCTGGAGCCACGCCTGGGGCGATCCGTTCGCGCACATCGGCACGGTGACCAAGGCAGTGGAGACGCTGCAGGGCCTGGAGGTCACCGGTCAGATCGACGACCTGGACGCCAACCCGACCGCACAGCAGGTCTACCGTCTACTCAAAGGGCGCCGCGTCACCCAGTTCAGCTTCGCCTACGACGTCACCGAAGGCGCGTGGGTGACGGACGACGACCACCCATGGGGCGGCTACTACGAGCTGCGGCGCCTGAAGCTGCACGAGGTCGGCCCGTGCCTGGTCGGCGCCAACCAGGAGACCGAGCTTCTGGCGGCGAAGGCGCACAGCATCGCCCGCGGCACCAAGGCCGGCCGGGTGCTCAGCCAGAAGAACTTCGAGACCTTGACCAGCGCCTACGAGGCGATCGGCGAGGTGCTCAGCAGCGCCACCCCCGAGAAGGCCGCCGTACCGAAGAAGACGACCGAGGCGTCCGGCCGGCCGGACACCGCAGCGGCTGACGGCTCCGAGCCCTCCGCCCAGCCTGCGAACGTCCCGCCCGCCCAGGCCCCCGACGACAGCGAGCTGTTCGCCCGCTTCCAGCAGTACCTGGCCGAGCACCCCGTCGCCGGCGGGACGGCCGCAACCGACAGCAGTACCGAGGACGAGACCACGCCGGATCCCCGCGAAGCGTCCGAGGACGCCGCCACGGCCGGTGCCGCCTCTGCCCGTCTGCGCACCGATCTCCAGCTCCTGGAGCTGGAGGCATCGCTCACGGAATGAGGACTGAGTACATGCCCACCGCGACCATCGAGGATCTGACCGGCCAGATGAAGCACGCGCTCACCGAAGCGCGCGCCATCGCCAAGAAGGCCGAAGACGAGGACAGGGATTTCACCCCGGAAGAGGCCGGCCAACTGCGCGAGCACATGGCCAAGGCCACTGAGGCCAAGGCCGCGATCGAAAAGGCCAAGGGCAATGACGAGCTGCGCAAGACGCTCGCCGACCTCGGTGACGACATCGCCCTGAACGCCAAGACCGACGACGACGGCCGCCGCCGCACGGCCTCCGGGTTCGACCTGCCCGACCGGCGCAAGTCGATCGGGCAGCAGTTCACCGACTCCCCCGAGTACAAGGCGCTGCTCGCGCAGGCGCCGTCCGGCCAGTTCGGGCAGAAGCAGCGCGTCCAGTCGGGCATGGCCGGCTTCAAGAGCCTGGTGACCGGCGCCTCGGACACTTCGGCGGGCGCCTGGGTGACCAACGACCAGATCGGCCTGCAGGTCGGCCTGGACGCCTTCCAGCGGCCGCTGCGGCTGCGGGATGTGGTCACCTCCGGCACCACCACGTCCGACACCGTCGAGTACGTGCGGGTCACCAGCGTGACCAACGCCGCCGCCCCCGTGGCCGAGGCCACGACGTCGGCGGCGCCGACCGCGCCGGGCGGCGCCGGTGCGCTGGTCAACGCGACCGGCGGCGGCTACAAGCCCGAGTCGGCGCTGGCCGCCGCGAAGGTCACCGCGCCGGTGAAGACCATCGCGCACTGGATCCCCGTCACCAAGCGGGCCCTGTCCGACGCCGCACAGATCAGGACGCTCATCGACGCCTTCCTCCGCTACGGACTGGAGGAGGAACTCGAAGACCAGATGATCCAGGGCGACAACACGGGCGAGAACTTCGAGGGCCTGGGCAACATCAGCGGCGTGCAGGCGCAGGCGTGGGACACCAACGCCCTGGTCACCCTGCGCAAGGCCAAGACGAAGGTGCGCACCATTGGCCGGTCGGTCGCCAACGCGTACCTGCTCAACCCGCAGGACGTCGAGACCATCGACCTGCTGACCGACAACGAAAACAGGTACTACTTCGGCGGCCCGTCCGGCACTGGCTCGGCGCAGCCGCTGTGGAACCTGCCGGTCATCGAGACCGAGGCCGTCCCGGCCGGCACCGGCTACGTCGGCGACTTCCGCAAGGCGATCCTGTGGGATCGCGAGCAGGCCACCATTCAGATGACTGACAGTCACCTGGACTTCTTCGTCCGTAACCTCGTCGCGATCCTCGCCGAGATGCGTGCGGCTTTCGGCGTGGTCCAGCCGAATGCGTTCGTCGAGATCGACCTGACCCCCTGATTCGGGAGGAGGACCGCTGTGCCGTACCTGGATCCCGCGGGCGGGAAGGCCCGTGAAGGCAAGCAGACCGCCGCAGTCACCAACGCTGCCGCAGCGACCGCGTCGGCAGCCGCCGGGTCGACGCCGACCAAGGCCGAGTACGACGCGCTGCTGGCCGACGTCAACGCGCTGCGCACCAAGCTCAACGCACTGCTCGCGGCGATGCGCACGTCCGGGCAGCTGGCGCCCTGACGTGCTGTTCACCCATCGCACCGCGGGAGGGCGGTGCCCGTGCGGCGCAGAAAACGCGGCGTGCGGACCGCCCTCCGACGTGGTGCCGGTCGATGCTCGAATCGAGGAGGTGGCCGCTGTGGGCGGGCCCCTGAAGAAGTACCGCGTCACGTCGCCGTCCGGCGCCGAGACCGTCATGAAGCTAAACGACGCGGACGCCGAGGCGCGCGGCCTGAGCGAGGCCGACCTCGCGGACGCGCCGGGCGCCGAGCCGGAGCCGGACGGGCCGGAGGAGAAGGCGGCCTCTGCCCAGAACAAGGCGCGGACCGCCGCGGCGAACAAGGGCCGCGGTGCCCGCGGTGGCGACTGACGAATTCCTCGCGGACCCCGCGGAGCTGTCCACGTGGACCGGCCGACCGGAGACGGACCCGAAGCTGCTCGCCGCGCTGCGGGCCGCCTCACGGCGCTTCCGCGGAGCAGTCGGGCACCGGATCACTTTGGTACTCGATGACATGGTGACGCTGGACGGCGGCGGCCGCACCTCGCTGCTGCTGCCGGTATGGCCCACCATCGCCGTCACCCAGGTCCGCGTCGACGGCACGGCCCTGGTGGCGGCCGCGGACTTCGACTGGTCAGAGGCTGGGCTGCTGCGGCGCCTGGGCTGCGGCCAGCGCTGGCCCGACCGGCTGCACAGCGTCGAGGTGACCTACAGCCACGGCTGGGCCGAGGTTCCCGAGGACATCCAGGAAGCCGTCATCGACCAGGCCCGGACCATGCTGGCGCTGCGGCCGGCGGTCCAGGCGATGCAGACCGGCGGGCAGACCATTACCTACGGGGCACAGGCCGCCGTGGGCGTCACCGACCAGTGGGCTCGGGCCGTGGCCCGCCACAAGGTCCGCACCAGCGGAGACGCCTGATGTTCTTCGATCAGATCGTGCGCGTGCGCGCCGGCGTGAAGACCGACCGTGGCGGCAACCAGGTGCCCGACTGGTCGCCGGGCGCCGTCTCCCGACTGACGGTGACGGACGTCAACGTACAGCCCAACACACAGGCCGAGGTCGCCGATTCGTCCCTGAGCGGTACGGCCAACCCGGCCCGGCGCGCGGTCATCACCGGCTGGCGAGTGCAGTCCGCGCCCGGCACCGCGCCCGACGTGCGGGCAGTCGACCGCATCGAGTGGCGCGGCCTGCTGCTGGAGGTGGAGGGCGAGGTCGCCGAATGGTCCGACCCCACCGACGGGTCGGTGCATCACGTCGAGTTCACCATGCAGCGCGCGACCGGATAGGAGGGCCCATGCTCGAAAGTCTGCGCCTGGACTATCAGGGCATACGCGCCTACTTGCGGGGCCCGGAGGTCCGCGAGTTCGTGGATACCCACGCTGCGCAGGTGGCGGCTCGGGTCCGAGCCTCACTGCCTGCCGATGTCGTGGTCACGGTGCGCTCCTACACCACCGACCGTGGCGCGGCGACGGTCGCCGTCGAAGACGTGCGGGCGATGGCGTGGCAGGCCCGCGACGGGCTGCTGACGCGAGCGGCCGGCGCGGCCGGCCTCGAGGTCAAGGCGTGGCAGCGGTGACAAAACCTCTGGTCGTCTTCGATGACGTCCAGGCTGCGGGGGCGCAGGTGCTGCGAACGGCTCTGGCGGGGCGGCCGGAGCCGTTCGCAGCAGGCGCAACGGTCGGCACGCGCGTGCCGGACGACCGCACCCCCGAGACGCCGCACTTGCCCTACGTCCTGGTCGCCAAGGACAGCGACGCACCGCACCCGTCCATGGCCAACGCCCGCTGCACTTTGCGGGTCACCGTGTGGGGCGAAGACGAGGATGCCGCGCACGACCTGGCGATGCTCTGCCAGGGCCTGCTGCTCATCCACTCCGGCCCGGTCATCCGCAGCGTGAAGCCCGGCACCGGCCCGCTGCCCGCGGTCGACCCGCCGACGGGCCTTCCCCTGAGCACGCTCACGGTGCTCGCCAACGTCCGGCCGCACGTCCTGGCCTGACCTGCTCTTTCGAACCGCGGCTGAACCCTTGACCCGAACCTTGAGGAGGACGCCGTGGCCGGCGACCCGAGTAACGCATCACTGTGGACCGATGCCGACGTGTACGTCGGCCCCGTCACGGCGGCCAACCCCGCCAACGCCAACGCCCCGTTCGGTTCCGACTGGGGGCTGGTGGGCCTGCTGGACGGCGACGACGGTATGCCGGAAAGCAGGGATGAGGACACGGACGACAAGTTCGCCTGGGGCGGCATCCTTGTGCGCACGTCGCGGAGCCACTTCAAGCTGACCAAGTCGTTCAGCGTGCTGGAGGACAACGCGGTGACCCGGTCGCTGATCTGGCCCGGATCGACCGAGTCGCAGATCATCGTGCCCGTGCCCGTCCCGGTGAAGATCGGGTTCGAGGTGCGGGACTCCGGTACCGGCAAGATCAAACGGCTCATCACTCGCCGCCACGCCATCGTCGAGGTCGACGGCGACGTGGACGAAAACGAGACCGACCTGACCAAGGTCACCCTCGTAGCCACGATCTTCCCGGACGGCTCGAAGGTCTTGTTCGACCGGCAGGGCACGCCGGTCCTGCAGTCCCTCGCCGTGGCCCCGTCCACGCAGTCCGTGGCGGTGGGCGCCATCGCGAGCCTGACCGCGACGGCCACCTATGACGACACCTCCACTCAGGACGTGACCACCACGGCGACCTGGACGTCCAGCGCGCCGACGAAGGCCACCGTAACGGCCGGCTTCGTCAAGGGCATCGCGACCGGCAGCGCCACGGTGACGGCGGCCTACAGCGGCCAGACCGCTACCTGCGCCGTCACGGTGACCTCCTCCTGACCGCCGGGGCGCGGGTGTTCGTCGCGGTTCGGCCGCGCCCCGGTGCACCCCCTCTAACCGCGACCAACCGCGACAGGAGAGAAGCTGTGACTCGCATCCAGATTCTCGAACTACCCACCTTCTACCGCGAAAGCGGCGACGACGAGACACCGTTCGTTGTCATCATCGACCAGGCTGGCCCATCGCTCATCTCCGTCGACGAGGCCAGCCGCCTGCACCTGGCAGAGAAGATCGGCGCGCGCGCCGTCCTTGTCTTCGAGGACAGTATCGAGATCCCGGGCAGCCGGATCGCCGTGCCTGGTGACGGGCAGGCTCCGTCAGGCACGGCAGAGATGTAGGGGCGGGCATGTCCATCTCCTGCACAGACGCCGAGATCCAGGCCCGGGCCGTACACCTCGGCCTCATCCAGGACGGCGAGGAGCTGCCCCGGCAGCTGCGCAGCCGCGTGGTCGCCTCCCTCATGCAGGAACGCCGCACGCAGAAAGCGCCGGCCGCCGAGGGGGAGCCCGCACGCGTCCGGCTGGCCCAGACGATCGTCGTGCAGCCGGGCGGCTCCATCCTCATCGACGGCGAGGAGCTGCCCTGGTTCGCAGGCCAGGACCCCATCGACGTCCATGTCCAGCACGACGGCAGCGGCAGCGTCCGCCTGACGCTGCTCGCCGACTCCGTACAGATCACCCCGCGCAAGCCCGACAGTGAGAGCGAGACCGCATCATGACCACCCGAACCGCGACGAAGCACGCCGACGACGAGGTCTTCGACTTCAACCTGAACGCCGTCGAAGCCGAAGTCGAACTGCGCCCCTTCCGCTTCTTGTGGGGGCCGAAGAACCGTCGCTTCACCATGCAGCACGCCGAGGAACTGAACGTGTGGCAGCTCATGGAGCGCGCCGACGGCGGCGATGTCGGCGCCGTGCTGAGCGCCCTCGAGACCGGCCTGGGCAAGGAGGAGTGGACCGCCTTCCGGGAGATCCCGATGCCGCAGTACAAGATGAAGGCGCTCTTCGAGGCGTACAAGCAGCACTGCGGCATGGGGGAATCCGGGGCCTCGTCAGGCTCCTGAGGGAGCACGGCGAGGCCATCGAGGCCGATCTGCGCCAGTACTACGGCGTGCGGCTGTCGGACCTGTTCCGCGGCCGCCTGACGTGGCGGGAGCTGCGCGTGCTGCTGCGCCAGCTCCCAGCCGCCGCCCGCACCTGGATCGCGCTCGGCCAGGAGGATCAGCTCTGGGGTCTGTCCGAGCATCTGCAGGCCATGGCCGTGGACGAGCTGCGCATAGCGAACTGGCAACGGGAGAATGAGGGCCGGGAGAAGTCCAAGCAGACCAAGCATCCCAAGCCCATCCCGCGGCCCAGCAGCAAGCGGGATAAGACCGCCGCTGAGAGCCCGGAGCGCAAGGCTGCCCGCACGGCGGCGCTGGAGCGGGCAGCGGCCCGCCGCGCGGCCATCGCCGCAGGCGAGATCACCTGACGTAACGCACAGCCGAGGGGGTGCCCATGCCCTCCGTCGGCTACGCCACACTGCAGATCATCCCGTCGGTGCGCGGCATCGGCGATGAACTGCGCCGCCAGCTCGTCGGCCCGTCCGCCGACGCCGGCCAGGAGGCCGGGGAGTCGGCGGGCGGGGGGCTGAGCGACAAACTGAAGAAGGGCGCGGCCGCTGCGGGCGTGGCGGCCGGCGCCATCCTGGTCAAGGGCCTCGTCGACGCCATCGGCCAGGCGGACGTCACCAGCAAGCTGCAGGCGCAGCTCGGCACCTCGAACAAGGTGGCGTCCGCGCAGGGCAAGCTCGCGGGGAAGCTGTACAGCTCGGGCGTCACCGGTTCGTTCGAGGAGGCGGCGGACGCGATTCGCTCGGTGGTCTCGGCGGGCCTGGCTCCGCCGAACGCCACCAACGCGCAGCTGCAGTCGATGGCCACCAAGGCGTCGGACGTGGCGGGCACGTTCGGCGAGGAGCTGGGTGGTGTCACCAACGCCGTCGCGCAGTTGATGCGCACCGGGTTGGTGAAGAACGCGAACGAAGCGTTCGACCTGATCACCGCCGGGTTCCAGTCCGGGGCCAACAAGGCCGAGGACTTGCTGGACACGATCAATGAGTACAGCACTCAGTTCCGGCGCCTGGGCCTGGACGGGCCCACTGCCATCGGGCTGCTGACCCAGGGCCTGAAGGCGGGCGCGCGTGACGCCGACCAGGTCGCCGACGGCATCGGCCAGTTCGGCGAGCGGGCCCTGGCCGGCGGCACCGCAGTGGACGAGGCGTTCGAGAGCATCGGGCTCAGCTCCTCGGACATGGCCGCGAAGATCGGCAAGGGCGGGGCGTCGGCAGCCGGCGCTCTCCAGCAGACGCTCGACGCGATGCGCGGCACCAAAGACGAGCAGGTCAAGCTCAACGCCGCCGCCGCGCTGTTCGGCGACCCCGGCAACGTGATGGGCGCTGCTCTATACGCGCTTAACCCGGCCAGCGCCGCCGCCGCGTCGGGCATGAACAAGACCGCGGGCGCCGCCGGGCGGCTGGGGAACACCTTGCGCAGCGGTCCGGCCTACGAGCTGCAGGTGTTCGCCCGCACCCTGCAGCAGTCCCTGGTCGACTTCCTCGGCGGCAAGGTACTGCCCGTCCTGGGGCAGGTCGGCGCGTGGGTCAACGCCAACGTTCTGCCGCCGCTGTCCGGTCTGGCGTCGATCGTGGGTGCCGTCCTGGTGCCGGTGCTGACCGGGCTGTGGAACGTCGGCACCGGAGTGGTCGGCTGGCTGCAGTCCATGGGCACGTGGCTGATCCCCATCGGCATCGCCGTGACCGGCCTGACCGTGGCCATCACCGCGCAGCGCATCGCCGTCGCGCTGACCACCGCGGTGTTCTCCGTCTACCGCGCCGCGATCCTGGGCTGGGCCGCGGTGCAGCGCGGCGCCATCGTCGTCCAGGCCGCCTTCAACGCGGTCATGAACGCCAACCCGATCATTCTGATCATCACGGCGATCCTGGCGCTCGGCGCCGCCGTGGTCGTGGCGTACCAGAAGGTCGGCTGGTTCCGCACCGCCGTACAGACCGCCTGGGCAGGCATCCAGACGGCCGCGCTGTGGGCCTGGACCAACGTCCTCCAGCCCATGTTCGCCGCCTTCCGCGCCGGGCTGGCGGCGATCGGCGCGGCCGCGTCCTGGCTCTGGACGACGATCCTTGCGCCGGTGTTCTCGTTCATCGGGACCGCCGCCCGCATCCTCGCGACGATCATCGCGTTCGTCGTCGCGGGACCCATCATCCTCGCCGTCCGGGCGATCGGCGCGATCTTCTCCTGGCTCTGGGTGAACGTCATTTCACCGGTCGTCGGATGGATCGGCGCCCGCGTCTCCTGGCTCAACACGAACATCATCCAGCCGAACATCCTGGCGATCCGGCTGGCCGTCTCCGCGGTGGGGGCCGGATTCTCCTGGCTCTGGCGTTCGATCATCCAGCCGGTACTGGGGTGGATCGCGTCGAAGGCGATCTGGCTCTGGACTTTTGGGATCAAGCCCAGCTTCGGCCTGCTGCGCCAAGGACTGGACGCCGTCGGCGGCGCGTTCTCGTGGCTGTGGCGCTCGATCGTTCAGCCCGTTCTGGGCTGGATCGGCGACAAGGCCGGGTGGCTCTGGCGCAACGCGATCAAGCCCGCGTTCGATCTGATCGGCCGCGGCGTCGCCGCGGTCGGCCGCAGCTTCGAGGACGCGAAGAACTTCATCGGCCGGGCGTGGGGCCAGCTCGAGAGCATCGCGAAGAAGCCGGTTCGCTTCATCATCGGCACTGTCTACAACAAGGGCATCGTCCCCACCTGGAACTTGATCGCGGGCGCGTTCGGCGCCCCTGAGATCAAGGCCATGGACATCCGGGGCTGGGCACGCGGCGGCCCGGTCCGCGGTCCGGGTACCGAGCGGTCCGACTCGGTACCGGCCTGGCTGTCGAACAACGAGCACGTGTGGACCGGCAAGGAGGTGCGCGGCGCGGGCGGGCACGGCGCCGTCATGGGCCTGCGCCGGCTGGCCTCCTCCGGGCGCCTGAACCTGAAGGGCGGCCTGCCCGCGTTCAAGGACGGCGGCGGCCTGTTCGGCTGGATCGGCTCGGCGGCGTCCACCCTCAAGGGCTGGGGCTCGGCCGCCTGGGACAAGGTGAAGTCCGCCGCGTCCTGGCTGGGGGAGACGATCGAGGCGTCCGCGCGGGCGGGCGTCAAGAACATCGTGGACCCGCTGCTGGCCAAGCTGCCGGGCGCCGACACCGGGTTCGGCAAGATGATCCGCCGGATGCCCACGAAGATCGTGGATGCCATCTTCGGGTACTCCAAGAAGGCCGACGAGAAGGGTGCGGCGGTCGGTGCCGCGGCGGCCGGTCCGGGTGCGCTGGGCAAGTGGATCGCGCAGGCCATGCGCATCACCCACGTCCCGGCGTCGTGGGCGGGGCCGCTGCGCACGCTCATCATGCGCGAGTCCGGCGGCAACCCCAAGGCGATCAACCTCTGGGACAGCAACGCCAAGGCGGGCTACCCGTCGCAGGGTCTGATGCAGACGATCCCGCAGACGTTCGCCGCCTACCGGCTGAAGTCCCTGCCGAACGACATCACGCACCCGATCGCCAACATCGTGGCAGGCATCCGCTACATCCTCTCCCGCTACGGGTCGATCTTTAAGGTGCAGCAGGCCGTCGGCAGTACGCCCAAGGGCTACGCCTCCGGCGGCCGGCCGCGGGCCGGGGAACTGGCCTGGGTCGGCGAACGCGGCGCCGAGCTGGTGCGCTTCGGCTCCGGCGGCGCCACGGTCTACGACCACCGCACGTCGATGTCCATGGCCGCGGGCCTGGGGGCGCGCGGGTTCGCCAAGGGCACCCCGGCGGCCCGTGCCCGCTCCGAGGTCGGCGGCGACCTGGCGAAGTTCACGAAGTCGCTGACCGGGTCAGCTGCCTCGATCGCCTCGGCGACCAAGGAACTGGCCAAGGACTTGGCGGCGGCGGGCGGTGCGGGCAAGCGCCTGGCGGCGAACACGAACCGCACCTCGGCCAGCCTGCAGGCGCTGGCCAAGCAGCGGGATGCGCTGTCCTCGACCATCTCCAAGGCGAAGGCGGCGGCCGCCGACCAGTCCAAGGTGGCGTCCGACTACCTGGGGCTGGGGCAGATCGGCGAGGTCAAGACGATCGGCGACGTGATCGGGCGGCTGCAGGAGCGGCAGGCCGCGGTCAAGTCCCGTGAGCAGGACTTCGCGGCGCTGTCGAAGAAGGGCCTGTCGAAGTCGGCGATCACGCAGTTGTCCGCGCTCGGCCTGGACAGCCCGCTGGCGTCCATCCTCGCCGGGGCGTCCAAGACGGATCTGGCGCTGTTCGACAAGCTGCTCGCGCAGAGCGGCGGCCTGGCGACCAGCTACGGCAACACGGTCGCCGACGCCATGTACGACAGCGGCAAGCAGGCGTCCAAGGGGTTCCTGACCGGGCTGCTCGGCCAGCAGAAGCTGCTGCAGAGCGCCATGAACACCATGGGCGCGGCGCTGGTGCGCGGCATCAAGTCCGCACTGAAGATCAAATCCCCGTCGCGGGTGATGCGCGACGAGGTCGGCGCGCAGGTCGGCGCCGGTCTGGTCGCGGGCATGGACGGCACCACCCCAGCGGTTGCGGCAGCGGCCGCCCGCATGGCCGACACCGCGGCCGGTGCCGGATGGCGCTCTCCCGAGGTCGGCTCTGCTGCGGGCTCCGGCTCCGGGCTGCCGCGTGAGGTGGTTCTGTCCGGGCCGCTGTACCTCGAAGGCGGCGAGTTCGCCGGCATCGTGCGCGGCGTCGTCCGCGAGGAACAGGACGCGCTGGTCATGCAGGCCGGTGCCGGAAGGAGGTCATAGATGGCCATCGTCATCAACCCGAGCATCCCCCCGCCGGCGCCACCGGTGGAGGCGGTCAGCCCGGACGGCATCCTCACCGCGCGCCGGGACGACGCCTACGCCGGGGTGTACCTGATCGCCGACTACACGGCTGCATCCCCGCCTCCGGCGCGGGTGCGGTTCGTGCGGGTCGGCGCGGACGGCACGGTGGCCGAGGTGCGCGGCGGGGACGCGGCCTGGGCGCCGGGTGGCATGGCGGTCGCCTACGACCACGAGGCCCCGCTCGGCGCCGCCTCCGTGTGGTTCGCCTACCCGGTCGATGCCTCCGGCATGATCGGCGCCCCCAGCCAGGGGGTGGCCCTGGCAGTGCCGGAGCCGGACGCGCCGCAGGACGTGTGGCTCAAGAGCATCACCGAACCGGGCCTGTCGATGCGAGTGCTGGTGCTGGCCTGGCCGCAGATGGAGTACGGCGAGAGGCAGGAGCGGTTTGACGTGCTGGGGGCCTCGGCGCCGGTGATGCGGGTGGACGCCTGGTCACTCCCGACATCCACCGTGACCATCGAGACGGCGACGCTGGACGAACGCCTCGCGCTGCGCTCCCTACTGACGACAGGCACGACCGTGCTGGCGCAGACCCGCGCCGAGTACGGCCGCGAGGACACCTACTGGGTACCCGGAAAGATCACGGAAACGATGCCGGGCGACGCAGGCGACCCGCACCGCACGTGGGAGGTCCCAGTGACCGCCGTGGACCGGCCGCCCACCATCGACACCCCACTGCGCATCCCGGGCCGCTCATACGCCGATTCGGCGGTGCCGTGGCCCACCTACGCGGACCGCACGGCGACCGGGCAGACGTACCACGCGGTGACCACGGGCGGCGGGTGAGGCGCCGTGTGGCCCGTCTCTCGGCGCTGGGATCCGGCCTTGCGCCACGCGCACCGCATGACCGCCCGCGCCACCATCCTGCCGCCGGTCGGCGCGCCGTTCACCGCCCGGCTGCTGTCGTGGTCAGTGACCGCCGACCGCACCGCCCAGACCCGCCGTACCCTGCAGGCCACCCTGGCGCCCGGCACTCGCCAGGCCCTGGACGGCGTCACCGTCCAGGGCGGCTACCTGCAGCTCGACGTCGGCTTCGACTACCTCGACGGGTCACAGGAACTGGTCCCTCAGGGCCTGTTCCGCCTCGACTCGGAGGACGCGGAGCGGCCCGACGGCGGCCTCGCGGCGCAGGGCTACGGCCGCGAAAAGGTGGTGGCCGACGACAAGTTCCTGGCCCCGCGCACCGAGCCGGCCAACTCCAGCGCCCTGGATCTGATCGAGACGCTGCTGACGGAGTCGGTGCCCACGGCCACCGTGCACCGCCGCACCACCCGCGACGCCGCGGTGCCGCGCACCACCTGGGAGCGCGAGAGATGGGAGGCGATCGACGGCACCGACGCGTCGCTGGCCCGTTCCATCGGCGTGGAGGTGTGGGCAGACGGGCGTGGCCAGTTCGTCATCACCGCCGTGCCGACCCTGGCCGACCCGCCGGTGTGGACGGTCGACGAGGGGCCCGGAGGTGTCCTCATCAAGGCGTCGCGGTCCTCGTCTACCGAGGGCGTCAACAACATCATCGTGGCCGTCGGGGATGGCGCCAACGGCTCGACTCCGGTCGGGCCGCTCATCGTCCGCGACACCGACCCCACCTCCCCGACCCGCGTGGACGGCCCGTTCGGCAGGCGCCCACGCTTCTACTCCTCACCGCTGCTGACCACGCTCGCGCAGGCCGACACCGCCGCCCGCTCCCTGCTCGCCAACTCGCTGGGGCTGGCCTCCGGGCTGTCCTTCTCGGCCGTCCCCAACCCGGCGCTGGAGCCGGGCGACGTGGTCCTGGTCAAGACCGGTGGCCCAGCGGAGCTGCACATCATCGACAAGATCACGCTGTCCTCCACCGGCGCCATGACCTGCGAGACCCGATCCACCAAGGCCGACGACGGAGGCACCACTTGAATCTGATCGATGCGCTGCTGCCGCGGGCCAGCAACCCCACCGGCGGCAGTGCCGTCGTCTCGGCCGTCAACACGGACGGGACCGTCGACATCAGCGTGGACGGCGCCACCGTGCCCGCGGCCTGCCTGGAGGGCTACGCCGACCGAACCCCCGGTGACGTGGTGTTCGTCCTGCCCGTGCGCGGCGGCTACGTCGTGATCAACCGCTTCTCCACCAGCTAAGGAGTCGCCCGTGCCCACCACCCCTGTCGGCAGCGCCCCTTATCCGGCAGGCGCCGACGCCGACGACGTCCCCGCCGACATGATGGCGCTCGCCCTGTGGGCCTCCACCCGCGTGGTCATGACCTTCGCCGACGCCGCCGCGCGCGACGCCGCGCTGACCTCGCCGACGCCCGGCATGGTCGCCTGGCTCTCCAGCCCCGGATCACTGACCGTGCGGACCGCAACGGCCTGGCGCACTGCCTGGTCGGCCATCTCCTGGATCGACATCACGTTGTCCAGCGGCTACGAGACCTACGGCACCACCCCGCAGGCGGCCATCGACGGCGGAAACTTCATCGTGCTGCGTGGCGGCGTACAGAAGACCACCGGCACCCAGCTGGCCAACGGCGAGGTCATCGGGACGATCCCCTCCGCCCTCGGCAACCCCCTGTCCGGGGACTACCCGATCGCCATGCAGTACCTTTCCAGCTCGGCCAGCCGCCTCTACGTCGCCACCGGGCGGACCCTCACCTACTTCGGCGTCAACACCGGCTGGATCAGCCTCAACGGCGTCCGCATCCCCCTCGCTTAGGAGATCGGCACATGCGCTACCAGTACGGGGGCGACGGCGGAAGCGTTGTCACCGACGCCGCGGGCAACGCCGTGGCCGGCCGCCCCGGCACCGTGTGGACCGCCCGCACCGGCGGCTCCCAGGTCACCGACCTCCTCGACATGGCGGGCAGCCCCACCGGCGGCACCATCACCACCGACAGCCGCGGCCGGCTGCTGTGGCAGGGCCCGGACGCCGTCACCTCCGCACTGTGGTGGGATCCGGGCGACGGCGGCCCGCGCTGGGCTGTCACCCCCACCGAGGTCGACCGCGTTGCTCGCCAGCAGGTCGACACCTACGCCGTGCCGTTGTCGGTGGTCGGGGAGGCGGGCGGCGTCGCCGAGTTGGACGGGGGCGGTCACGTGCCAGCCGCGCAACTGCCGGACATGTCGGCGTCCTACGTGCCGCGTCCGGCGGGTGGCCAGGCCGGGGACGCGCTGGTACGCGGTGCGGACACCAGTGTGTTCTGGGCCCGCCTGGACACGGCCACCGTCTCGCCGTGGGAGGCGCTGGAGGCGATGCCCGGCCCGCGCTGGATCGCGCACCGCGGCGGCTCCCTCCTCGCCCCGGAGAATTCGATCGAGGCGATGCGGATGGCCGTGGAGCTGAACGCCGACGCGATCGAGATGGACGTGTACAAGGTCGCCGATGGCGGGCTGTTCGTCATGCACGACGCCACCGTGGACCGCACCACCAACCTGACCGGAAGCCAGGCGACGGCGTTGACGGTGCCCGCCGCGCTCCGCGGCCGGATCGACGCGGGCAACTGGTTCGCCAACACCTGGCCCTCCGACCTGCGCATCCCGCTGTTCGCCGATGTGCTCGCCGAGGTCGGCAACACGGTGCCGCTGATCGTGCACTGCAACAACGCCGGTTCCGGCGCGGCCGCGGTCGCCGAGATCCAGCGCCAGGAGCTGGGCGAGGCCGTGCTCATCATGGCGTGGAACGAAACCGAACTCGCCGATGCACGGGCCGCGGGCATCCCCAGCTGCCTCCTGGACGCCGACGGCGTACTGTCCGGGCAGACCTACGCCGGGCTCATCGCCGCGGGCACCACCTACCTCGGCGTCGACTACTCGCAGGCCACCAACGCCACCATCAACGCCGCTGCGGCCGCGGGCCTGCGCGTGCTGGTCTACACGGTCAACCGCCGCAGCCACTTCGCCGCCCTGCCCACCACCGGCTCCGTGTGGGGCGTCATCTCGGACGATCCCTGGTACGTGCGCGGCAGCACCCCCACGCGCACCACGGATTTGTTCGGCGCCGGGACGTTCTTCCACGGGACGCCGACCATCACCGACAGCGGCGACTACCGCGGCTTTTTCCAGACCGGCAGCCCATCGTGGTTCGGGCAGGACGCGTCCGGCACGCTGCTGTCCGCCAACTCCGGCTACACCAGCACGCTGCAGGGCTACCTCGGCCCGCTGGGCACCTTCACTCTCGACGTGGACTTCGTCATCGACGTGGCCGACTACGCGACCGCGAGCATGCAGATCATGCTGTCCGTCGGCGACAAGGAGTTCGACGACCAGGGCGGGGGAGCGGCCAACCCCAACGGCTACAACATCCTGATCCGCAGCAACGGCACGATCGACGTGTACAAGCTGACCGGCGGCACCCCCACCAGCGTCGGCACCGTCGCCACGGCCGCCATCACCGCGGGCACCACCCAGCACCTGAAGGTGCAGGTCACCGCAACGCAGCTCATCATCACCCGCACCAACATCGCGGCCCCGAACAGCCTGACGGTCACCGACTCCACCTACCGCGGCGGCATGTATCCGCACCTCGGCGTGCGCGACACCAAGACCCGCTGGGCAAACCTGACCATCACCTGACCTGCTCCGCGCGCTACCCAACGCCCCTGCAACGGGGCCTTTTTCATGCCCGGAAAGGGGCCCACCTTGAAACTCGTCACCAGGGCACAGCTCGGCTGGCCCGCCTCTGCCGCGCCCGCGCAGGCGACCACGAGAGGCGTGAAGGTCCACTACGAGGGAACGCCTGTCTCGACGCGGCTCCTCACCGACCACGCCGCGTGCATCGCCGAGTGGAAGGCCATCAGGGCGTCACACCTGGCGAACAAGACCGAGAACTACAGCGATGTCGCCTACAACTACGCTGCCTGCCCGCACGGCTACCTCCTCGAAGGCCGCGGCATCGGCAAGCGCACCGGCGCCAACGGCAACCAGGACTTGAACCGCGCCCACTACGCCATCGTCGGCCTGGTCGGCAGCAGCGGCCTGGTCACCCCCACCGACGCCATGCTCGGCGCGATCCGCGACGGCATCGACCTGCTGCGCCAGCACGGCGCCGGACCTGAGATCAAGGGGCACCGCGACGGATACGCCACCACCTGCCCGGGGGCGTCGCTGTACGCCTGGGTACAGAAGGGCGCCCCGCGGCCCGGAACCACCACACCACCCACGGAGGATGACGTGTCCCTCACCGCAGCCCAGGCCAAGCAGCTCGCCGAACTGCACGACGTGCTCGTGCCCTACGCCGGCTGGCAGTACAAGGGCAAGGACGAAGAGACCGACGCCTACGCCTACCTCCGCGGCACCAACGCCTCGGTGAAGGCGGTCGACGCCAAGGTCTCCGCCCTCAAGCCCGTCGACCTCACCGACGCGCAGATCGCCGCGCTCGCGGAGAAGGTCGCCGCCGCCCCGGGACTGGCCGACGCCATTGCCGAGAAGGTTGCCCAGAAGATCGCCGATCGGCTCGCCGAATAGCGCTTCGGGGCGCCCCGAACTCACATCTACCAGCAGAAACGGACCCGCCATGCCCGACGTGACCACCATCAGCAAGACCGCGCAGACCTACGCCAGAGACCTCGCCGAACGCGTCATCTGGACGTTCCTCGTCGCCGCCGGAGGTGTCGCCCTCGCCGCTGGCCCTGGCGACATGTTCAACGTCACCTTCTGGGAGACGGTCGGCACCGCCGGGATCGCCGCAGTCGGCTCCCTCATCAAGGGCGTCCTGGCCCGCGTTATCGGCGACAAGAACAGCGCCTCAACCGCCACGGAGGTGTGAGTGCGCGCGGCGGCCCGGCGGCTTCGTGAGCACTTGGGCCGCCGCGGGGCTTTCCTGCTCATCCTCGGGACCGGCAAGACGTGCTGGGGGATCGGTTTCCTCGTTGAGGACCAGCCCCATCCTGTCGGCCTGGATCTGCTGACGCGTGTCGCGCCGCTGCACTGTTGGGCGTGGCTGTGGATCGTCGCCGGGCTCACCATGCTCGTCTGCGCCTGGCTCAAGGTCGGCCGGGACGGGCTCGGTTTCGCGGTCGCCCTCGTACCCCCCACCACCTGGGCCACCGCCTACACCGTCGCCGTCGTATCCGGCGACTACCCCCGCGGCGGATACGCCGCCATCTGGTACCTGACCTCCCATGTCGGGGTCATCCTGTGGGCGGCGACGGTGCCCGAGCACTCGGTCCCCCCAGCGCCGCGCGCCCGGAGAGGCAAGGGCGCATGAATATCTGGGCAGGCGTGATCGGCACGTTGGGCGTGGTGCTCGCCGCCTGGTTCGCCGCACGAGCCACGAGAGCCGCGGCGCAGGCCACGGCGGAAGCATCCCGGGCAGCAGCCCAGGCCGCGGCGGAACCGGCACAGCGCGAGCGCGACTTGGAGGCGTTCAAGGCCATAAGGGACGACATGCAGGAGGAGATCCGTGACCTGCGCACCGAGACCACCAGGCTGCGCGCGGTGGTCCGCGCGTTCGCCGGGTACGTGGGGGAGCTGACCCTGCAGATGCGCGCCGGGGGCATCGCCCCGTCCACGCCGCCCGACCTCGTCGACGAGTACAACCGCACCGGAGTGTGACGTCATGCCCGACCAGCCCGCGCCGCAGCCCGCCGAGCCGCGCATCGACGAAACCGCCGGAGACATCGGCTCGCTGGTGCGCCTCGGCGTCGTCGACCCGCCGCCCGTGCCGTCCCCGGAGCCGCCACCACCGCCCACCGAGACCCTCGACGCGCCCACGTGACCGCGCCCCGCCCCTGCTCCGGCAGGCGGCGGGGCGCATCGGCGTTTTGGAGTAGCAGGACGGCCGGTGAGGTGGGCTCAAGTCCCACACCCCGAAGGGCGCTGCGAACGCTCACCGGCCGCGAACACACCGTAGACCGGGGCACCAGTCGCTGTCAGCCCCTCGCGCCACACTGTTCACGCGCTGCTGAGCCCGCCCTCGCCGTAGTCGTGCGGCCGCCCGCCGCGCCATTCCACCCATGCCGGGTCGTCGAGCAGCGGCTCGGCGTCGGGCAGCCCGGCCCGCCGCAGGAACTCCACGACATCCGCGTCGCTGTGCGCGAGGCCGAGGATCGTGCCGTCGGCGCGCACCCGCCGCCCGCCCGTCGGGGACGGCTCCTGGATCACGATGCGCGCGGCCATGTGACCAGCCTGCGGGAGGGTGGGGCGGGGCGCATCCGGGGCGATTACCCAGTCGCGGAAGCTTCGGCTTCCAAGCGGCGTTTCGCCAGGTAGGCTCGCTGCCTGCGGATATGGCATGCCCGGCACACCCGCACACCGTTCGGGCGAACGCGGGTGTTTTCGGGGGTGAACTCGTGGCCGTGCTTACAATGCGTCGTCATCGAGCGCCAGCTCACCTTCGTGTGGGGCGAGCGCAATCGATTCTGGCTTGACGTCACCGCTTCAAGGTGAGCGGGGTTGATGCATCGGCGGTGAAGGCACATACCACCAGGGCACTCGGCATCTCGGTTGTGGCACACGTGGTCGATCACGAGACCCTCTGGTACCGGACCGTTTGCCAACTCGTAGGAGACGCGGTGCGCGTAACCACTCTTGCCGCCAGCGAGGCCGAAGGACCCATAACCGGAAGTCGGATTGACCGAACCTGTCCATATGATGCATCCGCCAGGAGCCGGGACTCCGCGTGCGAACAGGCGATCCCGTAGGGACTGCCGAACTTGGGGGCGGAACTTCCCGTCCTTTTTGAGTGCGTAGACGTGACGCTGGTAGCAGTTCTTGCAGCGCTGCCGCACGAGTTCCTGTCGCCAAACTTCGGAGCGGGGCTTCCCGCAGCCGACGCAAAGATCGTCGGCTGAACAGCCCCCGGGTATGACAAGCTCTTGCAT

Protein sequences of DBSCAN-SWA_4

>NZ_CP023688|5420283:5446024|5421015_5421390_+|WP_003979825.1|DBSCAN-SWA
MFGSKKTDEEKAAAKALLELRLAASAIGGLMVRKDPLRFTAPGQMDVPVGGAKVTVDRGEAAKRITATRVALTGIFALALKKDSTKLFVTIEGADGSAMLLECPAKKEAAARKFAILVHAKHPA
>NZ_CP023688|5420283:5446024|5438157_5439024_+|WP_003979805.1|DBSCAN-SWA
MAIVINPSIPPPAPPVEAVSPDGILTARRDDAYAGVYLIADYTAASPPPARVRFVRVGADGTVAEVRGGDAAWAPGGMAVAYDHEAPLGAASVWFAYPVDASGMIGAPSQGVALAVPEPDAPQDVWLKSITEPGLSMRVLVLAWPQMEYGERQERFDVLGASAPVMRVDAWSLPTSTVTIETATLDERLALRSLLTTGTTVLAQTRAEYGREDTYWVPGKITETMPGDAGDPHRTWEVPVTAVDRPPTIDTPLRIPGRSYADSAVPWPTYADRTATGQTYHAVTTGGG
>NZ_CP023688|5420283:5446024|5444405_5444756_+|WP_003979797.1|DBSCAN-SWA
MNIWAGVIGTLGVVLAAWFAARATRAAAQATAEASRAAAQAAAEPAQRERDLEAFKAIRDDMQEEIRDLRTETTRLRAVVRAFAGYVGELTLQMRAGGIAPSTPPDLVDEYNRTGV
>NZ_CP023688|5420283:5446024|5429849_5430407_+|WP_100246477.1|DBSCAN-SWA
MATDEFLADPAELSTWTGRPETDPKLLAALRAASRRFRGAVGHRITLVLDDMVTLDGGGRTSLLLPVWPTIAVTQVRVDGTALVAAADFDWSEAGLLRRLGCGQRWPDRLHSVEVTYSHGWAEVPEDIQEAVIDQARTMLALRPAVQAMQTGGQTITYGAQAAVGVTDQWARAVARHKVRTSGDA
>NZ_CP023688|5420283:5446024|5424407_5424635_+|WP_003979821.1|DBSCAN-SWA
MFAWRRTAVRKRVVVNLADKAFNGVLWAQRGPLLVLRDVQLLEAGRAPQQVDGEVVIERARVEFTQVLASTGGGG
>NZ_CP023688|5420283:5446024|5443716_5443968_+|WP_003979799.1|DBSCAN-SWA
MPDVTTISKTAQTYARDLAERVIWTFLVAAGGVALAAGPGDMFNVTFWETVGTAGIAAVGSLIKGVLARVIGDKNSASTATEV
>NZ_CP023688|5420283:5446024|5427951_5429280_+|WP_003979818.1|capsid|DBSCAN-SWA
MPTATIEDLTGQMKHALTEARAIAKKAEDEDRDFTPEEAGQLREHMAKATEAKAAIEKAKGNDELRKTLADLGDDIALNAKTDDDGRRRTASGFDLPDRRKSIGQQFTDSPEYKALLAQAPSGQFGQKQRVQSGMAGFKSLVTGASDTSAGAWVTNDQIGLQVGLDAFQRPLRLRDVVTSGTTTSDTVEYVRVTSVTNAAAPVAEATTSAAPTAPGGAGALVNATGGGYKPESALAAAKVTAPVKTIAHWIPVTKRALSDAAQIRTLIDAFLRYGLEEELEDQMIQGDNTGENFEGLGNISGVQAQAWDTNALVTLRKAKTKVRTIGRSVANAYLLNPQDVETIDLLTDNENRYYFGGPSGTGSAQPLWNLPVIETEAVPAGTGYVGDFRKAILWDREQATIQMTDSHLDFFVRNLVAILAEMRAAFGVVQPNAFVEIDLTP
>NZ_CP023688|5420283:5446024|5421417_5421816_+|WP_003979824.1|DBSCAN-SWA
MPPYAPPSRCTDPQCHELATQRGRCDEHQPIAWSGRDDKQARYGISSGTWRKLKRRVDQRDHGCCYLCGAEQPDDPEEPRHVLDHITPIAEGGSVTSLDNLGLLCGSCDAIKSRAEAIRGAQRARRRAKRSS
>NZ_CP023688|5420283:5446024|5440124_5440349_+|WP_003979803.1|DBSCAN-SWA
MNLIDALLPRASNPTGGSAVVSAVNTDGTVDISVDGATVPAACLEGYADRTPGDVVFVLPVRGGYVVINRFSTS
>NZ_CP023688|5420283:5446024|5431541_5432318_+|WP_003979811.1|DBSCAN-SWA
MAGDPSNASLWTDADVYVGPVTAANPANANAPFGSDWGLVGLLDGDDGMPESRDEDTDDKFAWGGILVRTSRSHFKLTKSFSVLEDNAVTRSLIWPGSTESQIIVPVPVPVKIGFEVRDSGTGKIKRLITRRHAIVEVDGDVDENETDLTKVTLVATIFPDGSKVLFDRQGTPVLQSLAVAPSTQSVAVGAIASLTATATYDDTSTQDVTTTATWTSSAPTKATVTAGFVKGIATGSATVTAAYSGQTATCAVTVTSS
>NZ_CP023688|5420283:5446024|5432664_5433036_+|WP_003979809.1|DBSCAN-SWA
MSISCTDAEIQARAVHLGLIQDGEELPRQLRSRVVASLMQERRTQKAPAAEGEPARVRLAQTIVVQPGGSILIDGEELPWFAGQDPIDVHVQHDGSGSVRLTLLADSVQITPRKPDSESETAS
>NZ_CP023688|5420283:5446024|5440931_5442776_+|WP_003979801.1|DBSCAN-SWA
MRYQYGGDGGSVVTDAAGNAVAGRPGTVWTARTGGSQVTDLLDMAGSPTGGTITTDSRGRLLWQGPDAVTSALWWDPGDGGPRWAVTPTEVDRVARQQVDTYAVPLSVVGEAGGVAELDGGGHVPAAQLPDMSASYVPRPAGGQAGDALVRGADTSVFWARLDTATVSPWEALEAMPGPRWIAHRGGSLLAPENSIEAMRMAVELNADAIEMDVYKVADGGLFVMHDATVDRTTNLTGSQATALTVPAALRGRIDAGNWFANTWPSDLRIPLFADVLAEVGNTVPLIVHCNNAGSGAAAVAEIQRQELGEAVLIMAWNETELADARAAGIPSCLLDADGVLSGQTYAGLIAAGTTYLGVDYSQATNATINAAAAAGLRVLVYTVNRRSHFAALPTTGSVWGVISDDPWYVRGSTPTRTTDLFGAGTFFHGTPTITDSGDYRGFFQTGSPSWFGQDASGTLLSANSGYTSTLQGYLGPLGTFTLDVDFVIDVADYATASMQIMLSVGDKEFDDQGGGAANPNGYNILIRSNGTIDVYKLTGGTPTSVGTVATAAITAGTTQHLKVQVTATQLIITRTNIAAPNSLTVTDSTYRGGMYPHLGVRDTKTRWANLTIT
>NZ_CP023688|5420283:5446024|5433813_5438157_+|WP_003979806.1|DBSCAN-SWA
MPSVGYATLQIIPSVRGIGDELRRQLVGPSADAGQEAGESAGGGLSDKLKKGAAAAGVAAGAILVKGLVDAIGQADVTSKLQAQLGTSNKVASAQGKLAGKLYSSGVTGSFEEAADAIRSVVSAGLAPPNATNAQLQSMATKASDVAGTFGEELGGVTNAVAQLMRTGLVKNANEAFDLITAGFQSGANKAEDLLDTINEYSTQFRRLGLDGPTAIGLLTQGLKAGARDADQVADGIGQFGERALAGGTAVDEAFESIGLSSSDMAAKIGKGGASAAGALQQTLDAMRGTKDEQVKLNAAAALFGDPGNVMGAALYALNPASAAAASGMNKTAGAAGRLGNTLRSGPAYELQVFARTLQQSLVDFLGGKVLPVLGQVGAWVNANVLPPLSGLASIVGAVLVPVLTGLWNVGTGVVGWLQSMGTWLIPIGIAVTGLTVAITAQRIAVALTTAVFSVYRAAILGWAAVQRGAIVVQAAFNAVMNANPIILIITAILALGAAVVVAYQKVGWFRTAVQTAWAGIQTAALWAWTNVLQPMFAAFRAGLAAIGAAASWLWTTILAPVFSFIGTAARILATIIAFVVAGPIILAVRAIGAIFSWLWVNVISPVVGWIGARVSWLNTNIIQPNILAIRLAVSAVGAGFSWLWRSIIQPVLGWIASKAIWLWTFGIKPSFGLLRQGLDAVGGAFSWLWRSIVQPVLGWIGDKAGWLWRNAIKPAFDLIGRGVAAVGRSFEDAKNFIGRAWGQLESIAKKPVRFIIGTVYNKGIVPTWNLIAGAFGAPEIKAMDIRGWARGGPVRGPGTERSDSVPAWLSNNEHVWTGKEVRGAGGHGAVMGLRRLASSGRLNLKGGLPAFKDGGGLFGWIGSAASTLKGWGSAAWDKVKSAASWLGETIEASARAGVKNIVDPLLAKLPGADTGFGKMIRRMPTKIVDAIFGYSKKADEKGAAVGAAAAGPGALGKWIAQAMRITHVPASWAGPLRTLIMRESGGNPKAINLWDSNAKAGYPSQGLMQTIPQTFAAYRLKSLPNDITHPIANIVAGIRYILSRYGSIFKVQQAVGSTPKGYASGGRPRAGELAWVGERGAELVRFGSGGATVYDHRTSMSMAAGLGARGFAKGTPAARARSEVGGDLAKFTKSLTGSAASIASATKELAKDLAAAGGAGKRLAANTNRTSASLQALAKQRDALSSTISKAKAAAADQSKVASDYLGLGQIGEVKTIGDVIGRLQERQAAVKSREQDFAALSKKGLSKSAITQLSALGLDSPLASILAGASKTDLALFDKLLAQSGGLATSYGNTVADAMYDSGKQASKGFLTGLLGQQKLLQSAMNTMGAALVRGIKSALKIKSPSRVMRDEVGAQVGAGLVAGMDGTTPAVAAAAARMADTAAGAGWRSPEVGSAAGSGSGLPREVVLSGPLYLEGGEFAGIVRGVVREEQDALVMQAGAGRRS
>NZ_CP023688|5420283:5446024|5439081_5440128_+|WP_050498932.1|DBSCAN-SWA
MTARATILPPVGAPFTARLLSWSVTADRTAQTRRTLQATLAPGTRQALDGVTVQGGYLQLDVGFDYLDGSQELVPQGLFRLDSEDAERPDGGLAAQGYGREKVVADDKFLAPRTEPANSSALDLIETLLTESVPTATVHRRTTRDAAVPRTTWERERWEAIDGTDASLARSIGVEVWADGRGQFVITAVPTLADPPVWTVDEGPGGVLIKASRSSSTEGVNNIIVAVGDGANGSTPVGPLIVRDTDPTSPTRVDGPFGRRPRFYSSPLLTTLAQADTAARSLLANSLGLASGLSFSAVPNPALEPGDVVLVKTGGPAELHIIDKITLSSTGAMTCETRSTKADDGGTT
>NZ_CP023688|5420283:5446024|5422664_5424386_+|WP_030184046.1|terminase|DBSCAN-SWA
MATKRTRSPAPADLGISAEVAWYLESRGIPLPDCPPKVQTPSPGEAPGAVFDPERVDRVLRSFHLLRHTQGKWAGKPLDPDPWQVAYILAPVFGWVRWDDEAEGYVRIVRKLYVDVPRRNGKTTLSGGIAVYLMAADGEPGAQVYAAATSEKQARYTFDPIKTIAERAPALKGNVKAYTKKITHPASGSYFTVVSSVAEALHGANVHGGIIDELHVHKSPDLVETIETGTGSRRQPLVVIITTADEGKQESIYDRRRQYVEQLARGALHDPDTYGVVWGADESDDPFAVETQRKANPGYGVSPSAAYLKGAAAEAQQSPADLAKYLRLHLGIRTKQSTRFLRLEDWDANAGLVDEAALAGRDAYGGLDLASTSDLCALCWLFPDDATGTLDAVFRFWTPEDNLRALDKRTAGAASRWVREGFLVATPGNVCDYDFIREQVRRDRDAFKVRSIGYDPWNASQLTNDLVSERAPMVKVRQGFATMSPVLKEIQRLVLQGTPEAPALRHGGHPVTRWCVDNLAVTMDPAGNVKPDKANSGDKIDGVSALATAMAEVVARPPRRKSRYADEDEIMVV
>NZ_CP023688|5420283:5446024|5422237_5422702_+|WP_003979823.1|terminase|DBSCAN-SWA
MAKAAAPAALKLITGRSPGRDSGGRKVEPGPAFKRVPPKPPTWLSREAAAEWKRVLPELSRLDLVKEQDRAALVAYCEAWATFVSATRVVQEEGLVIEARQGKLAHPCVAIARNAAREMRSWAAHFGLTPSTEQALARGEGGDGDEANPFAGSG
>NZ_CP023688|5420283:5446024|5426995_5427940_+|WP_030184034.1|head,protease|DBSCAN-SWA
MRTKDFAAKVKAAGPVDGLAEGQFTALVSVFGNEDSMGDVVRPGAFTETLAAWNEKGDPIPVIWSHAWGDPFAHIGTVTKAVETLQGLEVTGQIDDLDANPTAQQVYRLLKGRRVTQFSFAYDVTEGAWVTDDDHPWGGYYELRRLKLHEVGPCLVGANQETELLAAKAHSIARGTKAGRVLSQKNFETLTSAYEAIGEVLSSATPEKAAVPKKTTEASGRPDTAAADGSEPSAQPANVPPAQAPDDSELFARFQQYLAEHPVAGGTAATDSSTEDETTPDPREASEDAATAGAASARLRTDLQLLELEASLTE
>NZ_CP023688|5420283:5446024|5432404_5432656_+|WP_003979810.1|DBSCAN-SWA
MTRIQILELPTFYRESGDDETPFVVIIDQAGPSLISVDEASRLHLAEKIGARAVLVFEDSIEIPGSRIAVPGDGQAPSGTAEM
>NZ_CP023688|5420283:5446024|5445364_5446024_-|WP_086026188.1|DBSCAN-SWA
MQELVIPGGCSADDLCVGCGKPRSEVWRQELVRQRCKNCYQRHVYALKKDGKFRPQVRQSLRDRLFARGVPAPGGCIIWTGSVNPTSGYGSFGLAGGKSGYAHRVSYELANGPVPEGLVIDHVCHNRDAECPGGMCLHRRCINPAHLEAVTSSQNRLRSPHTKVSWRSMTTHCKHGHEFTPENTRVRPNGVRVCRACHIRRQRAYLAKRRLEAEASATG
>NZ_CP023688|5420283:5446024|5431073_5431487_+|WP_086026190.1|DBSCAN-SWA
MVVFDDVQAAGAQVLRTALAGRPEPFAAGATVGTRVPDDRTPETPHLPYVLVAKDSDAPHPSMANARCTLRVTVWGEDEDAAHDLAMLCQGLLLIHSGPVIRSVKPGTGPLPAVDPPTGLPLSTLTVLANVRPHVLA
>NZ_CP023688|5420283:5446024|5430406_5430775_+|WP_003979814.1|DBSCAN-SWA
MFFDQIVRVRAGVKTDRGGNQVPDWSPGAVSRLTVTDVNVQPNTQAEVADSSLSGTANPARRAVITGWRVQSAPGTAPDVRAVDRIEWRGLLLEVEGEVAEWSDPTDGSVHHVEFTMQRATG
>NZ_CP023688|5420283:5446024|5433478_5433787_+|WP_030417496.1|DBSCAN-SWA
MLLRQLPAAARTWIALGQEDQLWGLSEHLQAMAVDELRIANWQRENEGREKSKQTKHPKPIPRPSSKRDKTAAESPERKAARTAALERAAARRAAIAAGEIT
>NZ_CP023688|5420283:5446024|5433032_5433380_+|WP_003979808.1|DBSCAN-SWA
MTTRTATKHADDEVFDFNLNAVEAEVELRPFRFLWGPKNRRFTMQHAEELNVWQLMERADGGDVGAVLSALETGLGKEEWTAFREIPMPQYKMKALFEAYKQHCGMGESGASSGS
>NZ_CP023688|5420283:5446024|5440359_5440920_+|WP_003979802.1|DBSCAN-SWA
MPTTPVGSAPYPAGADADDVPADMMALALWASTRVVMTFADAAARDAALTSPTPGMVAWLSSPGSLTVRTATAWRTAWSAISWIDITLSSGYETYGTTPQAAIDGGNFIVLRGGVQKTTGTQLANGEVIGTIPSALGNPLSGDYPIAMQYLSSSASRLYVATGRTLTYFGVNTGWISLNGVRIPLA
>NZ_CP023688|5420283:5446024|5430783_5431065_+|WP_003979813.1|DBSCAN-SWA
MLESLRLDYQGIRAYLRGPEVREFVDTHAAQVAARVRASLPADVVVTVRSYTTDRGAATVAVEDVRAMAWQARDGLLTRAAGAAGLEVKAWQR
>NZ_CP023688|5420283:5446024|5429298_5429511_+|WP_003979817.1|DBSCAN-SWA
MPYLDPAGGKAREGKQTAAVTNAAAATASAAAGSTPTKAEYDALLADVNALRTKLNALLAAMRTSGQLAP
>NZ_CP023688|5420283:5446024|5424709_5426569_+|WP_100246478.1|portal|DBSCAN-SWA
MPAAPWEYAEIWRTQPQVRTVIGFLARNVAQLGIHTFRRISDTDRQRLTDHPLARVLAEPLPRFTPYRWVERLVSDLALYDNAYLIKLRLNGTLRLLPVPPTLIRPYRGNWIAPEYYETAGGRDFAVEDVVHIHGYAPENLTYGSSPIESLRELLLESSESAAQRAAMWRGGARVTGVLKRPMDAPEWSAKEKARFREMWRSFTQGGGAEGGTPILEDGMEYVPVGMTSEAAQYIDARKLTREEVSAAYYIPPPLIGILDHATYSNIKEQHAHLYQDTLGPWLAMLEQEIAAQILPDLPGDNASVYCEFNIASKLRGSFEEQAVAASTATGGPWMTRNEIRARNNLPAVEGGDELIVPMNVTEGGLASPRDTAPEPEALPKARGLALTKSAARPDDLATFEEGRDALTSALERWTQRAADKLLTAAGAKAQGMPDLLAVWAEGHEDRLAQLSALLAEHGYRLAQIGAWEVLDRWNPDASGWTPDVMLAWILAAAETHAEQHEEAGREAVAKVQEEGGDNWPKALAVAAAAWGIAAAGRSLTAATELRSFGGHDAASASGLTRKVWRTGGATPRPSHRALDGQSVALDDVFGNGCRWPGDGTAKVGEKANCRCRLDYETG
>NZ_CP023688|5420283:5446024|5420283_5420529_+|WP_003979827.1|DBSCAN-SWA
MCEEPGCEKQIDRGLAYLCGETPGDDEYGCGGYFCGEHLYMAPEGQHGERCIRCRDNGADPLENSPDAMVATFESGTAVGA
>NZ_CP023688|5420283:5446024|5443968_5444409_+|WP_003979798.1|DBSCAN-SWA
MRAAARRLREHLGRRGAFLLILGTGKTCWGIGFLVEDQPHPVGLDLLTRVAPLHCWAWLWIVAGLTMLVCAWLKVGRDGLGFAVALVPPTTWATAYTVAVVSGDYPRGGYAAIWYLTSHVGVILWAATVPEHSVPPAPRARRGKGA
>NZ_CP023688|5420283:5446024|5445095_5445320_-|WP_003979796.1|DBSCAN-SWA
MAARIVIQEPSPTGGRRVRADGTILGLAHSDADVVEFLRRAGLPDAEPLLDDPAWVEWRGGRPHDYGEGGLSSA
>NZ_CP023688|5420283:5446024|5420632_5420857_+|WP_003979826.1|DBSCAN-SWA
MPPRLVTAADAAHYTGRPVGTIWRWASEGRIRRTGRGKQARYYLDDLPRATRDEWTGLLTPGEAPPLPDGARAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003979827.1|5420283_5420529_+	hypothetical protein	A0A1X9SGY7	Bradyrhizobium_phage	3.6e-10	43.5
WP_003979826.1|5420632_5420857_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003979825.1|5421015_5421390_+	hypothetical protein	A0A2P1JT53	Streptomyces_phage	4.3e-31	64.7
WP_003979824.1|5421417_5421816_+	HNH endonuclease	NA	NA	NA	NA
WP_003979823.1|5422237_5422702_+|terminase	phage terminase small subunit P27 family	V9H0V4	Actinophage	5.0e-53	98.2
WP_030184046.1|5422664_5424386_+|terminase	terminase large subunit	A0A1B3B1U6	Gordonia_phage	1.7e-194	58.8
WP_003979821.1|5424407_5424635_+	hypothetical protein	NA	NA	NA	NA
WP_100246478.1|5424709_5426569_+|portal	phage portal protein	A0A222ZFM5	Arthrobacter_phage	3.0e-125	42.5
WP_030184034.1|5426995_5427940_+|head,protease	HK97 family phage prohead protease	A0A142K7Z8	Mycobacterium_phage	1.4e-46	49.2
WP_003979818.1|5427951_5429280_+|capsid	phage major capsid protein	M4WNS1	Mycobacterium_phage	1.2e-80	41.2
WP_003979817.1|5429298_5429511_+	hypothetical protein	NA	NA	NA	NA
WP_100246477.1|5429849_5430407_+	mobile element protein	A0A2R4A184	Microbacterium_phage	1.4e-09	36.2
WP_003979814.1|5430406_5430775_+	hypothetical protein	A0A2P1JSY3	Streptomyces_phage	7.3e-15	39.8
WP_003979813.1|5430783_5431065_+	hypothetical protein	NA	NA	NA	NA
WP_086026190.1|5431073_5431487_+	hypothetical protein	NA	NA	NA	NA
WP_003979811.1|5431541_5432318_+	hypothetical protein	A0A2H4PA05	Gordonia_phage	1.4e-23	40.4
WP_003979810.1|5432404_5432656_+	hypothetical protein	NA	NA	NA	NA
WP_003979809.1|5432664_5433036_+	hypothetical protein	NA	NA	NA	NA
WP_003979808.1|5433032_5433380_+	hypothetical protein	Q6VY44	Streptomyces_phage	2.2e-21	50.4
WP_030417496.1|5433478_5433787_+	hypothetical protein	NA	NA	NA	NA
WP_003979806.1|5433813_5438157_+	transglycosylase SLT domain-containing protein	Q6VY42	Streptomyces_phage	3.3e-130	42.4
WP_003979805.1|5438157_5439024_+	hypothetical protein	A0A0K1Y5X3	Streptomyces_phage	4.8e-33	37.3
WP_050498932.1|5439081_5440128_+	DUF5047 domain-containing protein	Q6VY40	Streptomyces_phage	2.8e-35	37.4
WP_003979803.1|5440124_5440349_+	hypothetical protein	NA	NA	NA	NA
WP_003979802.1|5440359_5440920_+	hypothetical protein	NA	NA	NA	NA
WP_003979801.1|5440931_5442776_+	glycerophosphoryl diester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	5.1e-08	39.3
WP_003979799.1|5443716_5443968_+	hypothetical protein	NA	NA	NA	NA
WP_003979798.1|5443968_5444409_+	hypothetical protein	Q6VY36	Streptomyces_phage	7.3e-46	64.1
WP_003979797.1|5444405_5444756_+	hypothetical protein	NA	NA	NA	NA
WP_003979796.1|5445095_5445320_-	hypothetical protein	NA	NA	NA	NA
WP_086026188.1|5445364_5446024_-	HNH endonuclease	A0A286N315	Arthrobacter_phage	5.6e-26	48.6

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NZ_CP023688|6658177:6665278|DBSCAN-SWA
GTCAGGCGCCAACGGTCTTGAGCACGCCGACGGGGTAGCGGCTGGCCTCGGTGGGCTGCTCGTTGTTGATGCGGTTCGAGACCTGCCAGCCCACCCGGAACGTCAGGCGCACGGCGGTCATGTCCTGCTGGGCGAGGTTGTAGATGATCGCTCCGGTGTTGTCCTGGATGACGGCCTGGTCCAGCACCTTCATGGTGATGTCGGAGCGGACCCCGATCACGAACTCGTTCCAGTCCCCGGCGAACAGCCGCACGCCGTCCACGCCCGCGCCGCCGGCCAGGGGGAACATGCCCTTCATGGCGTACTGGATCGGGTAGCCGTCCAGGGTGCGCAGGTCACCGCTGGTGCGGCCGACGTCGAGCTTGCGGCCCTGGGTGTCCCGGGCCCGGCGCAGCTTGGACTTGGCGGAGGTGGCGGCGACGAAGCCGTTGACCTCGAAGCCGTCGGCCTCCACCTTCTCGTAGAGGTTGTCGATGTCGCCGAAGAAGCCGCCCTGGGCGGCGGTGGAGCCCTCGTTGACGCTGTTGCCCGCGGCGGCGGCCGCCGACATGATGTTCGTCGGGAAGCTGGAGGGGGCGTTGGTGCCGAAGAAGATGGTGGAGTCCAGCAGCCGGCCGAACGCCTCGCGCACCAGCGGCTCGGCCTCGTCCCACAGGTCCGCGTCGGTGTCCGCCAGGACGTTGTCGGGGAAGGGGGCGATCGTCGCCATTTCCTCGATGTTGAGGAACTTGTTGCTCCAGTTGATCTCTGTGGTCTGCTTCAGGCCGGTGTCTCCGGCGACCCAGTAGGCCACCGGCAGGGCCGAGAGGATCGGCAGCCGGACCTGCCCGCGGGCGACCGGGATCCGCTTGAACATGGCCAGTGCCGCGGAATCCTCCACGGCCTTGCCGAGCATCTCCTTGGAGACTTCCTCGGGGATGAGGGCCGCCGCATCGGTGCGGCTGGTGACGTTGTTGTAGGCCACGGCTGTCGCCTGCCTTTCCAGGAAATGGCCGGCCGCCGGGCCGGACGTGTACTAGGAGGTGCCCGCCGCCTGGCGGATCAGGTCGTTCATGGACGTGGGCTTGGCCGCCGTCGTGCGCGCGCCGCCGTCGAAGGACGGGGCCGCCTCGGCGCGGGCCAGGTGCGGCTTGCTCTTGAGCAGGTCCGCGAGCGCCTTCTCGATGCCCTTGGTGTCGACATCGCCCGCGTCGTCGATGTACGCGCCGAGGTCGAGGAAGGCCGCGGCGTCCGACGGGTCCGCAAACGTCTTCGCGGCGAGCGCCTTGACCTCGGCGCGGACGACGCGCTGCGTCAGCGCCGAAATCTGGCCCTCGGCCTTCGCGGCGCGGTCGGTGGCCTGCTCCAAGTCGCTCTTGGACGCCGCTTCGAGGTCGTCGAACCGCTTGGCTTTCGCCGCGTTGGCCTTCGCCCGCTCCTCGTTCTTGCGGGACAGGGTCTGCCACTTGTCGCGGTCGGCCTCCGCGGCGGCCAGGCGCTCGGCCACCGTCGGCTCGGGACCCGTGCCGGTGCCGGTGGCGGCCTGGTGCTGGTCGTCCGGCGCGGTGCCCTCGGCGGGCCCGGCGGATTGCTCGGTGCTGGATTCGGACATGTGCATCTCCCGTTTCGGGACCGGTGATGGCGGCCGCGCGTTGCGCGCGGTCAGTGGAGGTAGCCGAAGCGCCGCAGCAAGGTGATCGCCTCACTGCGGCTGCCGGCCAGGTCGTAGATCTCCTCCGGCAGCAGCCGCGGAGAGGTGAGCCGGAAACCCCGGCCCGAGCGGGGCACCAGGCCCCGCTGGATGGCCCGCTGACGCTCGGCCCGGTACCACTGGCCCCGGCGGGTCGCCGAGTCCCGGGTGGCCCGCACCCGCCGGCCGTAGGCGCTGGCGGTGTACATGCCGCGGCGAGCGTTGACCACGCTCGTCAGCGACGCCCCGTCGCGCACCGCCTGCGCCCCGGACGCGGTGAAGATGCGGTTCTGCTCGGCGGCGCTCAGCGAGTCGAAGTACCGGCGCGCATCGAAGGCGCCCCGGTGATGGCGGCCGCGCGCCACGAGCTTGGTCGGCATGTGCACGCAGTCACACCGCGGATGGCGCTGAAAGCCGCGGTTCCAGCCGTACTCGGTCCCGGCCAGGATGATGCACCTGGCGCACGCCGGCGGGTTGACCACCCGTACATAGCCGTTTATGGTCCGGTTCCCGGCGATCGACGCGCCGGCCGCGGTCCGGCCGGCGTCCGCCACCTGCGTCGCCGCCGCCCTCAGTAGCTTCTCCAGCCCGCCCAGCAGCGACTCGACGGCCGACTGCCCCGCTTCCTGCAGCCGCCATTTCGTCTCGATCACCGGTTCGTACAGCAGGCTCTTCAGCGGGCGTCCGTCGGCCGCCGCACCTGCGAACGCCGCGGCGTCCACGCTGCCGTCCGGGTCGGACTCCAGGCCCTCGGCGGCGAGCACCGCCGCCACGTACGGGTCCGCGTGCGCCGCCGCCTCCCGCTGCCCGGCCGTCACCGCGGCCACCAGACCGCCCGCCACCGCCTGCCACGACCCGTCCAGGTCGGCGACATCCAGCCCGCCCCACAAGCCCTGCGCCCGGTCCACGGAGCGCCGCACGATCCGCTGCTGGCGCAGGTAGTGCTCGTGCGCCACCTGCTCCGCCGACGCCACCCGCTACTCCTCGGCCGGCGCACCGGCCGGGACGGGCTTGGGGCCGTAGTCCGCCGCCAGGTCCCCGCCGATGGCCCGGCTCAGCGCGTCCTCGCTCAGCAGCCGCCAGCGCTCGATCTCCTGCGGCGTCGCCCCCCACCGCTCCCACAGCACCTCGCGCGGCACCCCGAGCGTCGACATCTTCACCAGGGCGTCGACCAGCTCGCCCTCGGTGCGCCACTCCGGGGACTTCCACACGATCCGCGCCGACGACGCCCCGAACCCGGCCAGCCGCATCGTGCGCTCCAGCCCCTCCTCCAGGAACCGCCTGCGGGTGTAGATCTTGTGGATCAGCCCGGCCTCGGCAGCCTTGAGAGCCTCCGCCGACAGGTTGACCATGCTGCCCAGCAGGTAGTGCGGCGGCGTCGAGGTGATCGCCGCGATGTCCTGGACGTCCGCCTCCTTGGCCTTCAGGTAGCCGCTGAGGTCCGCGGCCGCGAACTGCCCGAAGCGGGCGGTCCCCTCCTCAGCGATCAGGATCTTGTTCACGGCCACGTCGAACGGCTCGATGTCCTGGCCCTGCTCGTCCACGGGGATCTCCATCCCCGTGGCCCACTTCTGCGGGAAGGCGGCGGACTCCTGCGTCATCATCCGGTCGGCGATGGTCTTGTTGATCCGGTCCTGGATCCCGGTCACCGACCGCAGCTCGGACGCGCCGGGCTTGAGCATCCGCGGCCGGTTGGCCAGCTGCCCGAACGGGACCTCGCCCAGCGCGTTGCGGCCGCCCCACTCCTCGCCCGCCACCTGACGGCGCACCCACTGCGGGCTCCCGCCCGTCTTCGGCTCCGGCGCCTCGAACTTGTAGATCCGCTCCGGCAGGTACAGCGTGCAGCACAGGCGCGCCGTCCAGTCGTCCAGCCACAGCTTCAGCGCGGCCGCCAGCTCACCCGGCTCGCCCGGCACGGCCTCCGTGATGACCTGCGTCGGATGCTCCGGAGTGATCCGGAACTCCTTGCGTCGGCCGGTCGGCGGGGACACCAGCAGGTACGCCTCGCCGCGCACCGCCGCCTCCAGGAAGCACAGCTGAGAGCCGCCGTCGAGGTTGTTGTCCTGCCACAGTCCCCACGCCCGTTTGTCCGCGTCGCCAGCCGCATCCGACTGGAAGCCCGCCACCTCCAGGCGCCCCACCAGGGCGTCGACGACCAGCTCCATGTAGTTCGCCCGGGACATGCGCAGCAGCCGCCGGAACGGGTCCCGCGCCTTCTCGTGCAGGAACGGCAGCGGGTGCTCGCACTCGTAGTAGTCGTCGAAGCGCTGCGTGTCCTTCGAGCGCTTGCACAGCGCCGTGTACAGGCGATCACGCCACCATTCCGGGGACTGGACAGCAGGTGCCGGCATCGGTCCCCCTTCCCGGTCAGAATCCGCGCCCGCGGCGCCGCTTCGCCTTAGCCTCACCCGCCGCGATCACATCCCCGGCCGCCTCGTGCGCCAGGACGGAGCACACGGCCAGGTCGATCTTCTGCAGCACGGACGCCTTGCGCAGCACGTAGCGGTTCGACGGCCGGGCCGCCTTGCGGGCGTTGCGCACGTGCAGGGAAGTGATCTCGCACCCGTCGTGCCCGAAGGAGCTCGCCGCTTTCGTCACATCCGTCAGCAGCCGCTCGCACGCCGCGTGCATCTGCACCACGCGCTGGGTGTACCAGCGCACCACCCGCTTGTCCCCGTACCGGTCGGCCCAGGTGTCCACCTCGGTCTCCCAGTACGGCGGGTCCGCGTACATACGCACCACGTCATACCGCTCGAACAGGTCGTGCACCGCGGCGTCGACCTCCAGCCGCGGCACCTGGCCCTGCCAGTCCTGCGGATCCCAGATGGCCAGCCGCGCGTCCGGACCGTACGTCGGCGTGAACTGGTAGCCGTCCAGGGTCTCCGCCCGGATGCCCGTCCAGTCGTCCACGTCGGAGCCGTCGAAGCCCAGCACCACCCGCGCCCGCTCCGGCAGCTCCCGCACCTGCGTGCGCGCATCCCACCGGTCCTGCTGCAGCCAGGTGCCCATTCCCGCCACCAGGCGGTTGCCGAAGAACCGCTCCGCCTCGGCCGGCTCCTTCTCCAGCAACTCCGCCGCCTCGCCCTCGATGGCGTCCAGGTCGATGTGCCGGCTGCCCTCGTAGACATGGGCGTGGATTTTCCGGCGCTCGGCCTTGTTCCGGTACGACAGGCCCTTGGGCGGCAGCCGGTGAAACCGGTAGACGTCCTTGGCCTGCGTCTCGGCCGTCTTCTGCGCCACCGAGTTCTCCGAGGGATCCCAGCCGTTCGTCGTCTCCAAGGACCGGCCGCTCATGCCCGCCAGGCCGCGGCGCTGCGTGGTGGCCACCTTGGTCATCTTGTTCGTCTCGGTCCAGATGCCCGTCTCGTCCTGGATGACGAAGGTCACCGGGTTGCCCAGCCGGGACTGTGCGCTGCTGGTGACGACGTCGATCCGGCCGTCGTTCGGCAGCCGGATGAACTGTTCGCCCACCCGCATCAGTTCGCCGAGCGGCCCATTGCGGATCATCGCCTGCAGCGGCCGGTAGACGTTGTCCGTCTGGTCCTCCGACGTCGCCGTGATCTGAATCAGCGGCGTCGACCACGGCCGGCCCATCGGCTCGCCCGGCTCATACTCGTACACCCAGCCGCACCCACAGCCGTACGACCGGCAGTCGTGCACCTCGCCGCCCTCGGCCCACCCGGCGAACAGCACCGGGCCGACCGCCTCGGCAGCCGTGATCCCGGCCGTCCACGGGCCCTTGCCCGACTTCTGCGGGGCGACAACCTGGCCACGACGGAAGCAGAACGCCGTTGACAGCTGGCCGATCCGCGCCTCGGTGCGCACCCGGTAGAAGTGGGCCGTGCACCGCAGCTGCCAGTCGTACATCTCGAACGGCTGCGGCCCTCGCACCAGACCGCCCACCGACTCCAGCCGGCAGTGCTGCGCAATCCAGTCCGGCACCACGTACAGCGTCGGGAAGTCCAGCGGCCAGGTGCCGTCATCAGCCGCGACCACCGGAAACCGATCTCAGCCGGGCCCGCGCCGAGGTGGGGGCGGCAGCAGGCGCTGAGGCGTCGGCCGGACGCGGGCCCTGTTCCGCCTCGCGGTCGATCCGCCAGCGGTTCGCCCGCATCCCGGGCGTCGTCAGCCCCAAGCTGTCGGCCATCTGTCGCACCAGCGTTCCCAGGTTGACACCGGCGTCCGGCTGCTCGGCCGCGGCCAGGCGGCGGACATACAGGGCCACTTCGAGGTGCTGGCCGTAGCGCTCCCACATCAGGGCCTGCGGCATCCGCCACAGGCGCTCCCACAGTTCGTCCTCGCGCACCGATTCCTCGGTCAGCGGCCACTGCGGCGTTTCGCCGTCGCGCCCGTCGGCCGGCAGGATCGTCCACTCGCCGGCGTCCCGCTCCCTGCGCAGCGCGTCCGGGTCGGGGGCCGGGCCGGACCGTGCGCGTGCTCCGCCCTTCGGCATGCTGATCTCTCTTCTGCCGCGTTGCGCGGCCGCTACTCCGTCACGTTGCGCGACGAGAGTTCATGATCACCGGTGGTTCTGAACCCGTCAGACCTGGCAGCGACCTCCCCGGCGGTCCGGCGTCGATCATGATCATGGGGTCACCCCCCAGGGCCTGTCACAGACCGTGACCGACCTTGGGGAGGTCGGTTCGGAGCGGAGCTGTGCGCTCCTCGGTCCACGCCTGAGAGGGATCGTCGGGGTCTATGAGCCGACTGCCGGTGGCGGTGGTGCGGAAGGTGTGGAAGCGGATGCTGCGCTGGCTGCCGTCGTCCTCGACGCTGATCCAGCGCAGGGCCACGGTGTGGGGGGCGGCGTTGTTGGCCTTGAGCCACTCGCACAGTGCCTCGCGATGCTCGTGAAGGTCATCGGTGCGGTAGAGGGCGAGCACCACGCTCACGTGTCCTCACCTGCCACCTCGTGGTCGGAGGTGACGGCGTAGCCGAAGGCCGGCCGCTCCTCGGGCTCGGGCCCGACGGTGAGCAGCCGGGCCGCGGCGGCCTCGGCTCGGGCCAGTGCCTTGGCACCCTTGCCCTTGATGTGGATGGCTACCTGCCGCTCGCCTGCGACGACTGTGATCCTCACTGGTTCCACCCTCCGGGCTGGTGCCGTGCGGTCTGGCTGCTGTGGCAGGGGCCGCACAGTCCGCGCCCGTGCCGGGGATCGGCGGGGTCGAGGCCGCGCTCGACCAGCTCGCGGCGGGACAGCGGGTGGTGGTCGGCGTGCACGCTCCGGGCCTGGCCGCACAGGACGCACACCGGGTCACGGGCGAGGACGGCGGGGCGGAAGCGGCGCTCGTGCTCGCGCCCGTACCCGCGCTGCCGTGCGGTGCCGCGCCGCTGCTCGGCTTCCTGCCGGTGGCCGTCGCACCTGCCGCCCTGGTCGGTGTACTCGGGGCAGCCGGGGACGGAGCACACTCGCCAGGCCGTACGTCTGGGCAT

Protein sequences of DBSCAN-SWA_5

>NZ_CP023688|6658177:6665278|6664733_6664922_-|WP_003981216.1|DBSCAN-SWA
MRITVVAGERQVAIHIKGKGAKALARAEAAAARLLTVGPEPEERPAFGYAVTSDHEVAGEDT
>NZ_CP023688|6658177:6665278|6658177_6659161_-|WP_078575475.1|capsid|DBSCAN-SWA
MERQATAVAYNNVTSRTDAAALIPEEVSKEMLGKAVEDSAALAMFKRIPVARGQVRLPILSALPVAYWVAGDTGLKQTTEINWSNKFLNIEEMATIAPFPDNVLADTDADLWDEAEPLVREAFGRLLDSTIFFGTNAPSSFPTNIMSAAAAAGNSVNEGSTAAQGGFFGDIDNLYEKVEADGFEVNGFVAATSAKSKLRRARDTQGRKLDVGRTSGDLRTLDGYPIQYAMKGMFPLAGGAGVDGVRLFAGDWNEFVIGVRSDITMKVLDQAVIQDNTGAIIYNLAQQDMTAVRLTFRVGWQVSNRINNEQPTEASRYPVGVLKTVGA
>NZ_CP023688|6658177:6665278|6660822_6662196_-|WP_003981220.1|portal|DBSCAN-SWA
MPAPAVQSPEWWRDRLYTALCKRSKDTQRFDDYYECEHPLPFLHEKARDPFRRLLRMSRANYMELVVDALVGRLEVAGFQSDAAGDADKRAWGLWQDNNLDGGSQLCFLEAAVRGEAYLLVSPPTGRRKEFRITPEHPTQVITEAVPGEPGELAAALKLWLDDWTARLCCTLYLPERIYKFEAPEPKTGGSPQWVRRQVAGEEWGGRNALGEVPFGQLANRPRMLKPGASELRSVTGIQDRINKTIADRMMTQESAAFPQKWATGMEIPVDEQGQDIEPFDVAVNKILIAEEGTARFGQFAAADLSGYLKAKEADVQDIAAITSTPPHYLLGSMVNLSAEALKAAEAGLIHKIYTRRRFLEEGLERTMRLAGFGASSARIVWKSPEWRTEGELVDALVKMSTLGVPREVLWERWGATPQEIERWRLLSEDALSRAIGGDLAADYGPKPVPAGAPAEE
>NZ_CP023688|6658177:6665278|6659817_6660819_-|WP_003981221.1|DBSCAN-SWA
MASAEQVAHEHYLRQQRIVRRSVDRAQGLWGGLDVADLDGSWQAVAGGLVAAVTAGQREAAAHADPYVAAVLAAEGLESDPDGSVDAAAFAGAAADGRPLKSLLYEPVIETKWRLQEAGQSAVESLLGGLEKLLRAAATQVADAGRTAAGASIAGNRTINGYVRVVNPPACARCIILAGTEYGWNRGFQRHPRCDCVHMPTKLVARGRHHRGAFDARRYFDSLSAAEQNRIFTASGAQAVRDGASLTSVVNARRGMYTASAYGRRVRATRDSATRRGQWYRAERQRAIQRGLVPRSGRGFRLTSPRLLPEEIYDLAGSRSEAITLLRRFGYLH
>NZ_CP023688|6658177:6665278|6664455_6664737_-|WP_003981217.1|DBSCAN-SWA
MSVVLALYRTDDLHEHREALCEWLKANNAAPHTVALRWISVEDDGSQRSIRFHTFRTTATGSRLIDPDDPSQAWTEERTAPLRTDLPKVGHGL
>NZ_CP023688|6658177:6665278|6663827_6664298_-|WP_003981218.1|DBSCAN-SWA
MPKGGARARSGPAPDPDALRRERDAGEWTILPADGRDGETPQWPLTEESVREDELWERLWRMPQALMWERYGQHLEVALYVRRLAAAEQPDAGVNLGTLVRQMADSLGLTTPGMRANRWRIDREAEQGPRPADASAPAAAPTSARARLRSVSGGRG
>NZ_CP023688|6658177:6665278|6662212_6663841_-|WP_003981219.1|DBSCAN-SWA
MVAADDGTWPLDFPTLYVVPDWIAQHCRLESVGGLVRGPQPFEMYDWQLRCTAHFYRVRTEARIGQLSTAFCFRRGQVVAPQKSGKGPWTAGITAAEAVGPVLFAGWAEGGEVHDCRSYGCGCGWVYEYEPGEPMGRPWSTPLIQITATSEDQTDNVYRPLQAMIRNGPLGELMRVGEQFIRLPNDGRIDVVTSSAQSRLGNPVTFVIQDETGIWTETNKMTKVATTQRRGLAGMSGRSLETTNGWDPSENSVAQKTAETQAKDVYRFHRLPPKGLSYRNKAERRKIHAHVYEGSRHIDLDAIEGEAAELLEKEPAEAERFFGNRLVAGMGTWLQQDRWDARTQVRELPERARVVLGFDGSDVDDWTGIRAETLDGYQFTPTYGPDARLAIWDPQDWQGQVPRLEVDAAVHDLFERYDVVRMYADPPYWETEVDTWADRYGDKRVVRWYTQRVVQMHAACERLLTDVTKAASSFGHDGCEITSLHVRNARKAARPSNRYVLRKASVLQKIDLAVCSVLAHEAAGDVIAAGEAKAKRRRGRGF
>NZ_CP023688|6658177:6665278|6664918_6665278_-|WP_003981215.1|DBSCAN-SWA
MPRRTAWRVCSVPGCPEYTDQGGRCDGHRQEAEQRRGTARQRGYGREHERRFRPAVLARDPVCVLCGQARSVHADHHPLSRRELVERGLDPADPRHGRGLCGPCHSSQTARHQPGGWNQ
>NZ_CP023688|6658177:6665278|6659191_6659767_-|WP_003981222.1|DBSCAN-SWA
MSESSTEQSAGPAEGTAPDDQHQAATGTGTGPEPTVAERLAAAEADRDKWQTLSRKNEERAKANAAKAKRFDDLEAASKSDLEQATDRAAKAEGQISALTQRVVRAEVKALAAKTFADPSDAAAFLDLGAYIDDAGDVDTKGIEKALADLLKSKPHLARAEAAPSFDGGARTTAAKPTSMNDLIRQAAGTS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_078575475.1|6658177_6659161_-|capsid	phage major capsid protein	S5Y5B1	Mycobacterium_phage	1.6e-56	39.6
WP_003981222.1|6659191_6659767_-	hypothetical protein	NA	NA	NA	NA
WP_003981221.1|6659817_6660819_-	hypothetical protein	D7NW50	Streptomyces_phage	5.2e-15	37.6
WP_003981220.1|6660822_6662196_-|portal	phage portal protein	A0A2H5BLQ6	Streptomyces_phage	3.5e-62	35.1
WP_003981219.1|6662212_6663841_-	hypothetical protein	D7NW48	Streptomyces_phage	1.5e-184	60.6
WP_003981218.1|6663827_6664298_-	hypothetical protein	D7NW47	Streptomyces_phage	9.6e-20	44.8
WP_003981217.1|6664455_6664737_-	hypothetical protein	NA	NA	NA	NA
WP_003981216.1|6664733_6664922_-	hypothetical protein	NA	NA	NA	NA
WP_003981215.1|6664918_6665278_-	hypothetical protein	A0A2H5BM35	Streptomyces_phage	8.9e-26	51.7

Sequences of DBSCAN-SWA_6

Nucleotide sequences of DBSCAN-SWA_6

>NZ_CP023688|6682143:6689851|DBSCAN-SWA
GTCACGGCTGGTCCTCCTGGTGCACGGTCTGGGCGAGGTGGGCGAGGGCAGCGGCGCGGCGCTGTTCGATCTCGGCCGGGGTCTCGGTGGCAGCGGGCTGGCCAGCGGCGACCCGACGGCGCGCGCCGTGAGGCTTCGGCGAGTTCTTCGAACGCAGCCGGGTCTTGCACGGTCGGCCGATCGGCGCGCGGCAGACAGGACACTCCACGCCCAGCGGGCCAGGCCGGCGAACTGCGGAGACCTCGGCCGTCGTGCTGCCGTCTTCCTCGGCGTCCGGTACTGGGCAGCCCACCTCGTACCCGCGGGCCTCCAGCTCCTCCACGAATTCCGGGTGCGGGCCGCCTTCCAGCGCAGGTGCCGCGCACAGGGCCGGGCCCCGGCCGTCGGCGGTGGCGGCGAGTTGGCCGCGCAGTCGCGCAAGGTAGTGCGGATCACAGTCGCTGGTCGGTGGCTCGTAGGTGAAGTTCTCCAGCCGCTCCGCGCGGAGTTTTTGTCGGCCGGTGCGGATGTCGTGCGGCTGAATCCAGAGCCGGTCGCCGGGCCTGTGGGGCGGGGTGGCGTAGTAGCGGGCCACGGCGGCGAAGGCGTCGTCGTCGGCTGGGACGTCATGGAGTGCAGCGGCCCAGGCTTCTGCGGCGGCAAGGCTGGGCTGGCGGTTGTCGAAGGCCGCGCAGTGGGCCAAGAGCCGCTTGGCGTCGTCTCGGTTCATGACGGGTCCTCGGTGGGGAGTGCGAGCCATCCGGCTACGCGTGCGTCGGTTCCGGTGAGGGCCTGGCCGGTGGGCAGTGGGATGACGTTTCCGGTGGTGTGGCGTTGGGCGACGCGGCGGGCGTCGTCGCGTATCCACTTTTGCCAGGCATCGGGCCAGGAGTGGCGGCGTGCTCCGGTGGAGCGGTAGTGGCTGACGAACTGGGCAGTGGAGTGCTCGATGTCGAGCCCGGGGTAGGTGGCGTGGGCCCAGCGGCGCATCGAGTCGGTGACGGTGAATGCGGCGTCGTCGATGGGGGCGTTGTACGCGCCGGGCAGGGGGCCTGCACCTTGGGCACCCACACCAGCCATAGGGGTTGCTGGTGGTTCCTCTGACGGTTGATTGGTGGTTAGGGCGGCACTGAGTGCGTTACATACGGACGCAGAGTGCGTTACGTAACGCACTTCAAGTGCGTTACGTACGGACGCAGAATCCGTTACACCGGCCTCGGTAACGTCGTCCGCGTCCGTTTCTGTAACGGCTTCTGCGTCCGTTACGGCGGACTTCTTCGATCGGTGCTTGCGGACCCGGGCCGCCGTCGCCTCGCGGTCCTCCTCCTCGGCCCGCTCCAAGTCCTCCCAGTCCGAAGCCGGCCGCGTCACATGCAGCGCCAGCTTCCAGCGGGTGCGGTCCTGCACACGGCCGTCGTCCACGATCAGGCCGGCGTCCTGCAGCCGCCGCAGCGCACGCTGGACGGTACGGCGGTCGTATCCGGTGCGGTACTGAAGGCGGATGAGAGACGGGTGAGCATTGCGGCCGTTCTTGTTAGCGTGCTCGGCCAACGCCTGCAGCACGTGCCGGGCTGTGGTGTCGGGCTTGCCGGACTTGGTGCGCAGCATCGGCGCGTCGTCCATGGCCCAGGTCACGGCCTCAGTGCTCACGGCGTCTTCTTTCTGCAGGTGCGGTTGTGCGTTGCGTCCGAGGCAGGGGTGGAGGGTCACCCCGCCTCGGGGCCGTGCAGGTGGTGCGGGGGCTGTCAGCCGTTCTTGGGCCGCTTGCGGACGGTTGCGGCGGTGTCCCCGGCGCGGATGATGTCGGCGAGGCGGGGGGAGACGCGGAAGCGGACCGCGCGGCTGGCCGGCAGGTGCATCGTTTCGCCGGTGTGCGGGTTGCGGGCGGCGCGTGCCGGGCGTTCGGTGGGCAGCCAGGCGCCGAAGTTGCTGATGGTGACCGGGTGTCCGTCGGCAACGGTCCGCGCGACGATGTCGAGCAGTGCGGTGACCGTGGCCTTGGCGGTGTCAACGCTGGTGCCGGTCTCGGCCGCGAGGTGCTCGGAGAGGGCGGTGTAGTTCAGCGGGCCGGTCGGCTTCGTCTTGATGGCCATGGTGATCTCCTCGGGTGAAGGGTGAGGTCTTGTAGTCGGGCGCCTTCAGGAAGTCGTAGCCGCCGTCTTGGCGACCGCGGCCTGAGCCGCGCGGTAGGTGTGCGGGCTGGAGCGGCGTTTGCCGGAGGCGATGGCGCGGGCGTCGATGAGCGCGGATGCGGACTGCGGGGACGGGGTGGTCCAGGCGCCGGCGGGGGCGCCGGGGCCGGGCTGCGGCTCGGGGTGTCCGGCGGCCGCCCAGGGGGCGTGTGCCGAGCAGCGGCGGCCGCAGGGGTAGAGCCGGACCGGGCCGGTGTGGTCGCCGAGCGCGTCGCACGGCCGGGGAGCGGCGGTCATGACGCGACCTCGCCGAACAGGCCGAGCTGTTCGCCGCTCGTCGCTCGTTGCCTGGCGTTGAGCGCACGCCTGGCGTCGCGGCAGCAGGTGCACCAGCCCCCGGGGTCGACGGGCTGGCCGTCCGGACTCAGCTTGCCCCAGTACTCCCACCACTCCTCGCCGGTTGTGGTGATGCCGGTGAGGATGGTGGCGCCGACGGTGGCGACGACCCAGCCGCGGAAGCCGGTCTGGGCGTGCCCGGGCAGGTTGCCGGGGAAGCCGTGCCGCTGGACGGCGTCGCCGAGTTGGAACGGGCTGTGCTCGGGGACGGCGCGGCCTGCGGTGGTAGCGAATGCCTCGTGCAGGTGGTCGGGGATGTGGTCGGGTACCGGGTGGCGGGGCTGCTGTGTAGGGGTCATGCCGCGGCCCCGGCCTCTCGCCGTGCGGCGGTGCGGGCGACGCGGCACGGATCGCACACCGGCTGCGCCAGGCGCCGGTGCGCTTCCGGCCCGGAGGGGGTGCCGCACCGGCCGGTCCAGTCGGGGAAGGCCGCTGGATCGTCGATCGTGTCGTCGTCCCACGCGCCCACCGGAGCCCAACCGGTGGCCGCGGCCTGCGCTCGGGCCCGGTTGTACGGCTGGGCGCCGACGCCGTGCTCGCGCGGGTCGGCGCGCCACAGCGCGTCGTACAGGCCGCGTACTGCCCGTACGGTGCGGACCACTACGCGTTGTCGGTGCAGGGTCGTGGCGAAGTTGGCGTCGCTCATGCCGAGCCGGACGGCCAGGTGGTGCTGCGGCCAGCCCGCGGCGATGAGGGCCTGCAGCCGGCGGGCGGTGCCGGTGGCGCCGATGACGGTGCAGGCTGGCAGGTTGTCGAGGGTGGGCTCGACGGCGAGGACGGCTGCGGCCAGCGCCGGACGTACCTTCTCCTGTGGCCCGGTGCCGCGCTCCGGGCGCCCGGTGATGATTGCCTGGAGGCGTTTGCGGTCCACGTCCGCCGCCGCGGCGATGGCCCGCAGGCCCATGCTGCAGGACTGCAGGTGGCGGATGTGGATGCGGACGGGCTCGGCGTCGGCCCAGGGGTGCCACGTGCCGTAGACGATGGCGCGGTTGCGGTTGTCGTCGTACTGGCTGCGGGCGAAGGCGCAGACGTAGCAGCGGCAGCCGTCCAGCCGGTACCGGGCGTAGCCGTGTGGGCGCTCGTTCATGCCGCCGCCCTTCGGGTCAGGACGCGGTGGACGGTCCGGGCGGTGCATCCGACCTCTGCACCGATTTGCGCGATGGTCATCCCGCCGCGCTGGTGCAGCCGGCGGATCAGGCTGTCGCGGACGTCGGTCTCCTGGTCTTCCGCCAGCTCAGCGGCGGCCTGCTTGGCACGGGCGTTCGGCGTGTGCCCAGCCCACAGGCCGTGCCGCAGCGCACGGGACACACCGCCCTCCAGCCGCTCGGCGTGCTGCGCGCATTGCTCGCGCACCGGGCACGAGCCGCAGACCTTGGCGGCGGTGCTGTAGCTGCCGTCCCTGTCGGGGTGGAACAGCGCGGGGTCGGTCTGGGCGCACAGCGCCTCGTCCATCCAGTCGAAGGCGCTCATCGGCCGGCCTCGGCTTCGAAGAGGTCGGCCACCTGGCGCAGGACGTAGGCCGCGGCCTGCTTGCTCATGCCCTGAGCGCCGGACTCGATGCTGACGCTGCCCTCGGCGCTGCCGGGGCGGATGATGACGAAGGCCAGCGCATCGCTTCCGTCGATGGCGACCATGGTCGTTTCCGGCTTGGGAATGGTCACAGGTCCCCCTTGATCGTGTTGCAGCTGGTGCAGCGGTAATCGCTGCCGTCCAGCACGTGGCGGGTGGTGAGGTGGGCGCAGGTGGTGGTGTCGCAGACGAGCCACCGAGCGCCGGGCGGGATCTCCTCGAACACCGCGGTGTCGGCGGCGCGCGCGGCCGCGGCGCGGCGGTGAGCGCCGCGTACGGGCGCCGCGGGGGCCGGGCGCAGGACACGGTCGACGAGGGCGGCGAACAGCGCGCCGGGGAATGCGGCGAGCACCGCGGCCCAGGTCATCGTCCGGCCCCCGTCCGGGCCCTGTGGCGGCGAATGTTGCGGCGCTCGGCCTCCGAGAGGCCGCCCCACACCCCCCACTCCTCGCCGGTGGCGAGGGCCCAGTCCTGGCAGATGCGCATCACCGGACAGCGGCTGCACACGGCCTTGGCGTCAGCGATCTGCGCCTTCGCAGGGCCGGCATACCCGACCGGGTAGAACAGCTCCGGGTCCTCCGCCCGGCAAGCCCCGAGCAGCTGCCACCCGGTGACCGCGTCGCGCGGAGCGTCCAGCAGGCGGGTCATGACGTCGCCCCCGGGACAGCCTGGCCCCCGGTGATTTCGTCGGCCGTGACGCGCGGCGCGGGGAACTCGTCCTCGGCGGTGACCTCGCCGCGCTGGATGGACTGAAAGATGACCTGCAGCTGGGCCACGTCGTGCTCGGTCCACTTCGCCGAGGACCGGCCGAGCTTGGTCTCGATGCGGTCCGAGGTGACGCCGATCCCCTCGAAGGCGCGGATAGCGTCGGCCACCCGCACGTTCAAGGACTTGCCGCCGCCGTCGCGCAGGGTCTGCTCGCACAGGTTCTTGGCCTCCTCCACGAACCAGGGCGGCAGAATCGCGAAGATCGCCTCCCGGATGCGGCGGGCCCCGTTGTTGGCGTTGTTCTCGTAGATGTCCCGCAGCTCCTTCAAGGGCACGGGACCGTTGTCCTTGGTGTCCCGCAGGTGCGGGACGATGAAGGTGCTGCTGTTGCGCGAGTTCTTCTCGACATCCCAGGCAAACGCCTGCATTTCCGACTGCGCGAACTCGTCGTCGCGGCGCATCTCGACCAACCCGTACTGCACGTTGCCCCAGCAGCGCGCCAGCTCTCGGGCAAGGTGGACGGACGGGCCGGACACCGTCTTGCCTGCGCGGGGGAAGCGGAAGAACGCGCGCTCAGCCAGGTACTTCTGCTTGCACGACTGACGCATCTCGTCGATGGCGGCCTGGATGTTGCGAGGGCACTGCTGCGCCACGACGATCGCCGCCTGCACCTCGGCCACCGCGCGGGACTGCTCCACCGCAGTCCCCTGGCCGATGCGAGTCGGCGCCCCCGCCGGACTCATACGCTCGATCTGCTGGTACTGGTTCACAGGTACTCCTCGGAGTCGCGAATCTCCGCGTACGGGGGAAGGGAGAGGTAGGCGATGTCGTCGCTGTAGCCGGGCCAACGGCCGGTCTCGACGCACTCGGCGTACGTCTCGATGGCGCGCCGGTTGCGGGCGGCGCCGATGCGCATCGCCATGGCGCTGGGCTGGTAGACGGTCACCAGGTACGGCGGCGTCTTCTCCTGGCACACGAACACGAACTGGGCGTCGTCCCCGGCCAGGCCGAGGGCGCGGCATCCGGAGCGGTACCAGTCGGCTTGCTGGTGGTAGCCGTACTCGTGCATCGCCCGTTGCAGCGCGGCGGGTTCGGCGGACCGAGTGGTCTTGTAGTCGGGGATGACCATGCGGCCAGGGCCCGGCGCGGGACGCCAGTCCAGCAGGGCGCGCCGCATGACGCCGGTCGGGCCGTCCCGCCACACGAGCGCGGACTCCGGCGTGCCGCTGCCGGGCTCGAACAGCTTCCGCGCGACCGGGTGCTGCCACAGGGCATTCGCCATGGCCTGGACCACGTCGTAGTCCTTGCGCAGAAGCGGCATGGCACCGCTCTCGCGGACCGCTTCGCGCTCGTCCCGAGCAGCCGACGTACGCCAGTCGTCGAAGTCCAGCGGCACCAGCTCGGGGCCGGCGTCGAGGACCAGGCGGTGCGCGGCGTGCCCGAAGTCGAACGTGGCCTTCGGCGGCGGCGGGTTGTCCTGCTCGTGCCGGAAGAGCGCCGGGCAGGACGGAGGCAACAGCTTGCGGGCACCCGACGAGGACAGGGAGCCGCCCGGCACCGGATCGGCGTGGTACTCGTCAGCGGTCAGGTCGTACAGGCCGGGCCCGGTGACGGGCCCGGCGGCCGGGGCCGAAGCCCCGGCCGGCAGGGTAGTCGTCACCAGATCCTCCCGATCTCGCGGAGGCCGCCGGTACGCGCCCGGACTGCCTCCGTAGGCTCCCCGTCGTCGAAGGGGTTGGTGTCGAAGGGAGCAATCAGCTCGCCTTTCACCGGGTCGGTGTCCTGGCTCATCCAGGCACGTCCCTTGCCGTCGATGTAGATACGGCGGCGCCGGTCGGCCGGGTCGGCGGAACGTTCGCCGTTGGCGGCCTGCTCGACTGCCGCCACCCACTCCGGCACGGGCATCGGCTGATCTCCACGCCGCGCCGCCTGGCGCGCCTGGTCGCATACGGCGCGCACGGCATCGAGGCAGCTGCTGAGGTAGGACATCTCCTCGGCCACCGTCGGCTCCGTGCCGACGTACCTCTCCAACTGCGCGATCAGCCAGCGGGTATCGGCGAGGAACACCCCGGCCTCGATGTGGTTCTTGATTTGTGCGAGGCGGTCGTCAGCCACGGCGCGCCTCCTGCTCACCCGTCACGTCGATGTGGGTGAGGAGGATGCCGCCCGCGCAGCCCTCGACCGAGACGACGGCCACGCCGTGACCAAGCGTCCAAGCCGGAGTGCGGGTGCGGGTGAGCAGAGGCTGCTCGTCACGCGTGGCGGGGAAGGCTGCTACGCGAGTACCGACGGGGTGCTTTGCGTTCCACTGCTCGGCGTTCACGCGGCCACCGCCTTCGCGGCGTCCCACAGGTCGATGCCGCGGCGGATCGCGTGGCAGCAGTGCAGGAAGCCGGGCGTGTAGTCGCTGAAGTCCCACTCCGACAGGTCACCGAAGTCCCAGCCGTCGTAACGGAAGTCCGCCAATGCCGCGCGGGCACCCGTCTCGTGGCTGATGTCGGCCAGTTCGAAAATCTCGCGGGTGACTTCGGCGCCGATGCCGCGCGGGGCCTCACCCTCGCGGATGGAGTGGACGACGTACTGCTTGACCTGCCGCTCGAACAGTTCCGGGTCGAAGCCCTCGACCTCGTCGCGGCCAGCGCGGACCTTCTCCGACCAGTAGCCGGGGTTGATCTCGCCGCTGAAGGCGGTGCGCCGGAACAGGGCGAACATGTCCTCGGTCGCGTCGATGTCGAAGTGGAAGACCCAGCCCGCCTTGACGACGAGGTTGTACGGCCACGTGATCAGCTCGAAGGGGCCGATACGGCCCTGCTCGGGGGTGGAAAACCGCAGGTGCCGGTACAGCCCGTCGACGCGCAGGACGGTCATCTCAAGCCGGGCCGTGTCGCGGGCGAACCGCTCGGCGATCTCGGAGCACTCGGTCAT

Protein sequences of DBSCAN-SWA_6

>NZ_CP023688|6682143:6689851|6685732_6686119_-|WP_003981178.1|DBSCAN-SWA
MSAFDWMDEALCAQTDPALFHPDRDGSYSTAAKVCGSCPVREQCAQHAERLEGGVSRALRHGLWAGHTPNARAKQAAAELAEDQETDVRDSLIRRLHQRGGMTIAQIGAEVGCTARTVHRVLTRRAAA
>NZ_CP023688|6682143:6689851|6683866_6684214_-|WP_003981182.1|DBSCAN-SWA
MAIKTKPTGPLNYTALSEHLAAETGTSVDTAKATVTALLDIVARTVADGHPVTISNFGAWLPTERPARAARNPHTGETMHLPASRAVRFRVSPRLADIIRAGDTAATVRKRPKNG
>NZ_CP023688|6682143:6689851|6682143_6682851_-|WP_003981184.1|DBSCAN-SWA
MNRDDAKRLLAHCAAFDNRQPSLAAAEAWAAALHDVPADDDAFAAVARYYATPPHRPGDRLWIQPHDIRTGRQKLRAERLENFTYEPPTSDCDPHYLARLRGQLAATADGRGPALCAAPALEGGPHPEFVEELEARGYEVGCPVPDAEEDGSTTAEVSAVRRPGPLGVECPVCRAPIGRPCKTRLRSKNSPKPHGARRRVAAGQPAATETPAEIEQRRAAALAHLAQTVHQEDQP
>NZ_CP023688|6682143:6689851|6689033_6689249_-|WP_003981170.1|DBSCAN-SWA
MNAEQWNAKHPVGTRVAAFPATRDEQPLLTRTRTPAWTLGHGVAVVSVEGCAGGILLTHIDVTGEQEARRG
>NZ_CP023688|6682143:6689851|6686115_6686310_-|WP_003981177.1|DBSCAN-SWA
MTIPKPETTMVAIDGSDALAFVIIRPGSAEGSVSIESGAQGMSKQAAAYVLRQVADLFEAEAGR
>NZ_CP023688|6682143:6689851|6689245_6689851_-|WP_003981169.1|DBSCAN-SWA
MTECSEIAERFARDTARLEMTVLRVDGLYRHLRFSTPEQGRIGPFELITWPYNLVVKAGWVFHFDIDATEDMFALFRRTAFSGEINPGYWSEKVRAGRDEVEGFDPELFERQVKQYVVHSIREGEAPRGIGAEVTREIFELADISHETGARAALADFRYDGWDFGDLSEWDFSDYTPGFLHCCHAIRRGIDLWDAAKAVAA
>NZ_CP023688|6682143:6689851|6687692_6688586_-|WP_003981173.1|DBSCAN-SWA
MTTTLPAGASAPAAGPVTGPGLYDLTADEYHADPVPGGSLSSSGARKLLPPSCPALFRHEQDNPPPPKATFDFGHAAHRLVLDAGPELVPLDFDDWRTSAARDEREAVRESGAMPLLRKDYDVVQAMANALWQHPVARKLFEPGSGTPESALVWRDGPTGVMRRALLDWRPAPGPGRMVIPDYKTTRSAEPAALQRAMHEYGYHQQADWYRSGCRALGLAGDDAQFVFVCQEKTPPYLVTVYQPSAMAMRIGAARNRRAIETYAECVETGRWPGYSDDIAYLSLPPYAEIRDSEEYL
>NZ_CP023688|6682143:6689851|6684944_6685736_-|WP_003981179.1|DBSCAN-SWA
MNERPHGYARYRLDGCRCYVCAFARSQYDDNRNRAIVYGTWHPWADAEPVRIHIRHLQSCSMGLRAIAAAADVDRKRLQAIITGRPERGTGPQEKVRPALAAAVLAVEPTLDNLPACTVIGATGTARRLQALIAAGWPQHHLAVRLGMSDANFATTLHRQRVVVRTVRAVRGLYDALWRADPREHGVGAQPYNRARAQAAATGWAPVGAWDDDTIDDPAAFPDWTGRCGTPSGPEAHRRLAQPVCDPCRVARTAARREAGAAA
>NZ_CP023688|6682143:6689851|6688582_6689041_-|WP_003981171.1|DBSCAN-SWA
MADDRLAQIKNHIEAGVFLADTRWLIAQLERYVGTEPTVAEEMSYLSSCLDAVRAVCDQARQAARRGDQPMPVPEWVAAVEQAANGERSADPADRRRRIYIDGKGRAWMSQDTDPVKGELIAPFDTNPFDDGEPTEAVRARTGGLREIGRIW
>NZ_CP023688|6682143:6689851|6682847_6683756_-|WP_139679703.1|DBSCAN-SWA
MTWAMDDAPMLRTKSGKPDTTARHVLQALAEHANKNGRNAHPSLIRLQYRTGYDRRTVQRALRRLQDAGLIVDDGRVQDRTRWKLALHVTRPASDWEDLERAEEEDREATAARVRKHRSKKSAVTDAEAVTETDADDVTEAGVTDSASVRNALEVRYVTHSASVCNALSAALTTNQPSEEPPATPMAGVGAQGAGPLPGAYNAPIDDAAFTVTDSMRRWAHATYPGLDIEHSTAQFVSHYRSTGARRHSWPDAWQKWIRDDARRVAQRHTTGNVIPLPTGQALTGTDARVAGWLALPTEDPS
>NZ_CP023688|6682143:6689851|6684259_6684550_-|WP_003981181.1|DBSCAN-SWA
MTAAPRPCDALGDHTGPVRLYPCGRRCSAHAPWAAAGHPEPQPGPGAPAGAWTTPSPQSASALIDARAIASGKRRSSPHTYRAAQAAVAKTAATTS
>NZ_CP023688|6682143:6689851|6686862_6687669_-|WP_032920626.1|DBSCAN-SWA
MSPAGAPTRIGQGTAVEQSRAVAEVQAAIVVAQQCPRNIQAAIDEMRQSCKQKYLAERAFFRFPRAGKTVSGPSVHLARELARCWGNVQYGLVEMRRDDEFAQSEMQAFAWDVEKNSRNSSTFIVPHLRDTKDNGPVPLKELRDIYENNANNGARRIREAIFAILPPWFVEEAKNLCEQTLRDGGGKSLNVRVADAIRAFEGIGVTSDRIETKLGRSSAKWTEHDVAQLQVIFQSIQRGEVTAEDEFPAPRVTADEITGGQAVPGATS
>NZ_CP023688|6682143:6689851|6686306_6686585_-|WP_003981176.1|DBSCAN-SWA
MTWAAVLAAFPGALFAALVDRVLRPAPAAPVRGAHRRAAAARAADTAVFEEIPPGARWLVCDTTTCAHLTTRHVLDGSDYRCTSCNTIKGDL
>NZ_CP023688|6682143:6689851|6684546_6684948_-|WP_003981180.1|DBSCAN-SWA
MTPTQQPRHPVPDHIPDHLHEAFATTAGRAVPEHSPFQLGDAVQRHGFPGNLPGHAQTGFRGWVVATVGATILTGITTTGEEWWEYWGKLSPDGQPVDPGGWCTCCRDARRALNARQRATSGEQLGLFGEVAS
>NZ_CP023688|6682143:6689851|6686581_6686866_-|WP_003981175.1|DBSCAN-SWA
MTRLLDAPRDAVTGWQLLGACRAEDPELFYPVGYAGPAKAQIADAKAVCSRCPVMRICQDWALATGEEWGVWGGLSEAERRNIRRHRARTGAGR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003981184.1|6682143_6682851_-	hypothetical protein	Q6VY73	Streptomyces_phage	3.7e-39	45.3
WP_139679703.1|6682847_6683756_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003981182.1|6683866_6684214_-	HU family DNA-binding protein	NA	NA	NA	NA
WP_003981181.1|6684259_6684550_-	hypothetical protein	NA	NA	NA	NA
WP_003981180.1|6684546_6684948_-	hypothetical protein	NA	NA	NA	NA
WP_003981179.1|6684944_6685736_-	hypothetical protein	A0A166Y055	Gordonia_phage	5.9e-14	32.2
WP_003981178.1|6685732_6686119_-	WhiB family transcriptional regulator	A0A2P1CGA4	Mycobacterium_phage	9.0e-08	39.7
WP_003981177.1|6686115_6686310_-	hypothetical protein	NA	NA	NA	NA
WP_003981176.1|6686306_6686585_-	hypothetical protein	NA	NA	NA	NA
WP_003981175.1|6686581_6686866_-	WhiB family transcriptional regulator	A0A159B6S6	Tsukamurella_phage	2.2e-11	47.3
WP_032920626.1|6686862_6687669_-	hypothetical protein	A0A1B3B1U8	Gordonia_phage	6.6e-85	61.3
WP_003981173.1|6687692_6688586_-	hypothetical protein	A0A0R8VB90	Thermobifida_phage	2.6e-74	54.1
WP_003981171.1|6688582_6689041_-	hypothetical protein	NA	NA	NA	NA
WP_003981170.1|6689033_6689249_-	hypothetical protein	NA	NA	NA	NA
WP_003981169.1|6689245_6689851_-	hypothetical protein	A0A1B3AYH1	Gordonia_phage	5.7e-25	39.6