CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP044142	Escherichia coli O157 strain AR-0429 plasmid pAR-0429-1, complete sequence	0 crisprs	DEDDh	0	1
NZ_CP044144	Escherichia coli O157 strain AR-0429 plasmid pAR-0429-2, complete sequence	0 crisprs	RT	0	1
NZ_CP044143	Escherichia coli O157 strain AR-0429 chromosome, complete genome	7 crisprs	PrimPol,DinG,DEDDh,cas3,c2c9_V-U4,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	8	14

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

45165 : 62202

Salmonella_phage(28.57%)

integrase,transposase

attL 54338:54397|attR 55754:55876

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000427619.1\|45165_46170_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_001138073.1\|46248_49221_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
WP_001162012.1\|49223_49781_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_001447826.1\|49818_50142_-	hypothetical protein	NA	NA	NA	NA
WP_000845054.1\|50086_51100_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	6.1e-72	45.5
WP_001436322.1\|51245_52043_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA7	NA	NA	NA	NA
WP_000679427.1\|52206_52554_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_040079219.1\|52547_53387_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_072037403.1\|53316_53496_-	hypothetical protein	NA	NA	NA	NA
WP_000376623.1\|53514_54015_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001297012.1\|54320_54434_-	hypothetical protein	NA	NA	NA	NA
54338:54397	attL	NA	NA	NA	NA
WP_001389365.1\|54521_55286_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001375131.1\|55349_55607_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A077SL39	Escherichia_phage	8.9e-12	61.9
WP_014839880.1\|55648_55825_+	hypothetical protein	NA	NA	NA	NA
WP_001276635.1\|55844_56834_-	DUF3330 domain-containing protein	NA	NA	NA	NA
55754:55876	attR	NA	NA	NA	NA
WP_001087810.1\|56830_57067_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_000995361.1\|57063_57429_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000761850.1\|57540_58179_-	organomercurial lyase MerB	NA	NA	NA	NA
WP_000149288.1\|58193_59879_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.1e-38	27.9
WP_000732290.1\|59950_60226_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294666.1\|60241_60592_-	mercuric transport protein MerT	NA	NA	NA	NA
WP_000414383.1\|60663_61098_+	mercury resistance transcriptional regulator MerR	NA	NA	NA	NA
WP_000427623.1\|61197_62202_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP044144

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

9309 : 16618

Macacine_betaherpesvirus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077631973.1\|9309_9390_-	AMP nucleosidase	A0A0N7BTS3	Escherichia_phage	1.5e-07	100.0
WP_085948178.1\|9355_10569_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_071525396.1\|10530_10869_+	RepB family plasmid replication initiator protein	I3WF20	Macacine_betaherpesvirus	1.6e-40	100.0
WP_000772446.1\|11456_12623_+	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	7.0e-229	100.0
WP_000817031.1\|12622_13594_+	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	4.8e-175	100.0
WP_001349526.1\|13978_14251_+	hypothetical protein	NA	NA	NA	NA
WP_001336590.1\|14334_14631_-	hypothetical protein	NA	NA	NA	NA
WP_000138832.1\|14893_16618_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	8.3e-170	53.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP044143

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP044143_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_1

1728656-1728790

Orphan

Consensus_repeat	Method
GGCCTACACGCTGCAATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044143_1

>merge|NZ_CP044143|1|1728656-1728790|CRISPRCasFinder
GGCCTACACGCTGCAATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCATTCAGCGCCTGATGCGACGCTGACGCGTCTTATCTGGCCTACACGCTGCGATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA

>NZ_CP044143|1|1|1728656-1728790|CRISPRCasFinder
GGCCTACACGCTGCAATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA	TTCAGCGCCTGATGCGACGCTGACGCGTCTTATCT
GGCCTACACGCTGCGATTTTGTAGGCCGGATAAGCAACGCGCATCCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_000916267.1\|1722538_1723237_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP044143.1\|WP_001148407.1\|1723323_1724088_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP044143.1\|WP_001138626.1\|1717157_1718816_+\|HTH-type-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188
NZ_CP044143.1\|WP_000800457.1\|1740607_1741894_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP044143.1\|WP_000525186.1\|1735006_1735666_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP044143.1\|WP_000241259.1\|1741893_1742883_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP044143.1\|WP_000746183.1\|1738200_1740555_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP044143.1\|WP_000235663.1\|1720944_1722555_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP044143.1\|WP_001248768.1\|1716937_1717069_-\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP044143.1\|WP_001300811.1\|1724173_1725052_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP044143.1\|WP_000151715.1\|1727101_1728604_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP044143.1\|WP_001117011.1\|1732088_1734995_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP044143.1\|WP_001304001.1\|1736083_1736836_-\|UDP-pyrophosphate-phosphatase	unknown	unknown	unknown
NZ_CP044143.1\|WP_001065380.1\|1742879_1743701_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP044143.1\|WP_000868321.1\|1719044_1719614_-\|T3SS-effector-EspY2	unknown	unknown	unknown
NZ_CP044143.1\|WP_001301693.1\|1719985_1720969_+\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP044143.1\|WP_000951872.1\|1725390_1727091_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP044143.1\|WP_000888654.1\|1728803_1729499_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP044143.1\|WP_000035699.1\|1729573_1731925_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP044143.1\|WP_001200573.1\|1737130_1737946_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_000916267.1\|1722538_1723237_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	5.93317e-163
NZ_CP044143.1\|WP_001148407.1\|1723323_1724088_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.79494e-49
NZ_CP044143.1\|WP_001138626.1\|1717157_1718816_+\|HTH-type-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0
NZ_CP044143.1\|WP_000800457.1\|1740607_1741894_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP044143.1\|WP_000525186.1\|1735006_1735666_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	5.25024e-158
NZ_CP044143.1\|WP_000746183.1\|1738200_1740555_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP044143.1\|WP_000235663.1\|1720944_1722555_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP044143.1\|WP_001248768.1\|1716937_1717069_-\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00111324
NZ_CP044143.1\|WP_001300811.1\|1724173_1725052_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP044143.1\|WP_000151715.1\|1727101_1728604_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP044143.1\|WP_001117011.1\|1732088_1734995_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP044143.1\|WP_000241259.1\|1741893_1742883_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP044143.1\|WP_001065380.1\|1742879_1743701_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.27697e-148
NZ_CP044143.1\|WP_001301693.1\|1719985_1720969_+\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0
NZ_CP044143.1\|WP_000951872.1\|1725390_1727091_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP044143.1\|WP_000888654.1\|1728803_1729499_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	3.528e-179
NZ_CP044143.1\|WP_000035699.1\|1729573_1731925_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP044143.1\|WP_001200573.1\|1737130_1737946_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.09407e-169

>NZ_CP044143.1|WP_000151715.1|1727101_1728604_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVKALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP044143.1|WP_000951872.1|1725390_1727091_+|ribulokinase
MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
>NZ_CP044143.1|WP_001300811.1|1724173_1725052_-|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP044143.1|WP_001148407.1|1723323_1724088_-|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLVRHPLMPVYIDILRKVVGV
>NZ_CP044143.1|WP_000916267.1|1722538_1723237_+|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGALTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELLSGKASASALLGITG
>NZ_CP044143.1|WP_000235663.1|1720944_1722555_+|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWSAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVTALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTMLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFSVIEKIPGRNVKTD
>NZ_CP044143.1|WP_001301693.1|1719985_1720969_+|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP044143.1|WP_000868321.1|1719044_1719614_-|T3SS-effector-EspY2
MKVRNPEQISIPASNTTKDPGLTNSQIIRMANLVKKTENMNIFEELWETLRNLFQSDKHSQTAARQILKDAFYFQNSDDYSKYFTGAVDGKARDKLTHWLIKFNELKEYAKDPENMAAKASLSPEGTLCVSFFIGDEAIFTLELQLKKSTRTGGIDLSNAYFNGVVICGIDCLEVDLSNAETNNSRWYD
>NZ_CP044143.1|WP_001138626.1|1717157_1718816_+|HTH-type-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTITSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQVDAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>NZ_CP044143.1|WP_001248768.1|1716937_1717069_-|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY
>NZ_CP044143.1|WP_000888654.1|1728803_1729499_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVSIETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP044143.1|WP_000035699.1|1729573_1731925_+|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILRGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGAIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLVSSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEATKIGRALVQHVNVWWAETLQKQQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYFRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP044143.1|WP_001117011.1|1732088_1734995_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP044143.1|WP_000525186.1|1735006_1735666_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
>NZ_CP044143.1|WP_001304001.1|1736083_1736836_-|UDP-pyrophosphate-phosphatase
MKVSVPGMPATLLNMSNNDIYKMVSGDKMDMKMNIFQRLWETLRHLFWSDKQTEAYKLLFNFVNKKAGNINASKYFTGAVNENEKEKFIHSLELFNELKTCAKNPDEMVAKGNMSWVAQTFGDIELSVTFFIENKEICTQTLQLHKGPGNLGVDLREAYLPGVDMRDCYLGLKTMKGHNKVLYLEPGWNANLDGATLDGATLDGATVDGATHLYDEVIIINKITPKKIDTEEVATKQSTAEQITDNAIIE
>NZ_CP044143.1|WP_001200573.1|1737130_1737946_-|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP044143.1|WP_000746183.1|1738200_1740555_+|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINANHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVSIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
>NZ_CP044143.1|WP_000800457.1|1740607_1741894_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP044143.1|WP_000241259.1|1741893_1742883_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP044143.1|WP_001065380.1|1742879_1743701_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPFQES

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Crispr_ID: NZ_CP044143_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_2

1958733-1958882

Orphan

Consensus_repeat	Method
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044143_2

>merge|NZ_CP044143|2|1958733-1958882|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCATGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

>NZ_CP044143|2|2|1958733-1958882|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCA
TGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_001301967.1\|1951923_1952943_+\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP044143.1\|WP_000416407.1\|1959492_1962348_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP044143.1\|WP_000786399.1\|1959049_1959493_+\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP044143.1\|WP_085948178.1\|1948190_1949404_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP044143.1\|WP_151121024.1\|1949603_1951553_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271184
NZ_CP044143.1\|WP_001261097.1\|1947176_1947509_+\|NIPSNAP-family-protein	unknown	unknown	gnl\|CDD\|311781
NZ_CP044143.1\|WP_001295681.1\|1954735_1955818_-\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP044143.1\|WP_151121025.1\|1964918_1965923_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP044143.1\|WP_000584114.1\|1955817_1956918_-\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP044143.1\|WP_000256678.1\|1968489_1969083_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP044143.1\|WP_001046858.1\|1947630_1948008_+\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NZ_CP044143.1\|WP_001294533.1\|1953072_1954575_+\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP044143.1\|WP_000079623.1\|1962402_1963599_-\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP044143.1\|WP_001059397.1\|1963791_1964295_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP044143.1\|WP_000583470.1\|1967892_1968345_-\|DUF386-domain-containing-protein	unknown	unknown	gnl\|CDD\|225345
NZ_CP044143.1\|WP_000588536.1\|1945706_1946174_+\|DUF1643-domain-containing-protein	unknown	unknown	gnl\|CDD\|226783
NZ_CP044143.1\|WP_000036512.1\|1965979_1967770_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044143.1\|WP_000397144.1\|1957184_1958696_+\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP044143.1\|WP_000500712.1\|1969153_1969867_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP044143.1\|WP_000002953.1\|1964340_1964757_-\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_001301967.1\|1951923_1952943_+\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	5.44918e-169
NZ_CP044143.1\|WP_000416407.1\|1959492_1962348_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP044143.1\|WP_000786399.1\|1959049_1959493_+\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP044143.1\|WP_085948178.1\|1948190_1949404_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.21825e-157
NZ_CP044143.1\|WP_151121024.1\|1949603_1951553_-\|site-specific-integrase	gnl\|CDD\|271184	cd01184, INT_C_like_1, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.99595e-64
NZ_CP044143.1\|WP_001261097.1\|1947176_1947509_+\|NIPSNAP-family-protein	gnl\|CDD\|311781	pfam07978, NIPSNAP, NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.	3.32232e-05
NZ_CP044143.1\|WP_001295681.1\|1954735_1955818_-\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP044143.1\|WP_151121025.1\|1964918_1965923_+\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP044143.1\|WP_000584114.1\|1955817_1956918_-\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP044143.1\|WP_000256678.1\|1968489_1969083_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	9.63528e-10
NZ_CP044143.1\|WP_001046858.1\|1947630_1948008_+\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	8.71141e-09
NZ_CP044143.1\|WP_001294533.1\|1953072_1954575_+\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP044143.1\|WP_000079623.1\|1962402_1963599_-\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	5.35185e-152
NZ_CP044143.1\|WP_001059397.1\|1963791_1964295_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.52162e-19
NZ_CP044143.1\|WP_000583470.1\|1967892_1968345_-\|DUF386-domain-containing-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.50239e-70
NZ_CP044143.1\|WP_000588536.1\|1945706_1946174_+\|DUF1643-domain-containing-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.3168e-96
NZ_CP044143.1\|WP_000397144.1\|1957184_1958696_+\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP044143.1\|WP_000500712.1\|1969153_1969867_+\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	2.19644e-150
NZ_CP044143.1\|WP_000002953.1\|1964340_1964757_-\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69

>NZ_CP044143.1|WP_000397144.1|1957184_1958696_+|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP044143.1|WP_000584114.1|1955817_1956918_-|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP044143.1|WP_001295681.1|1954735_1955818_-|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP044143.1|WP_001294533.1|1953072_1954575_+|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIDVNDWQPHANPVVVWDIFGEKGHSVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP044143.1|WP_001301967.1|1951923_1952943_+|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLPVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIKHVRDGKARYRVVLKADF
>NZ_CP044143.1|WP_151121024.1|1949603_1951553_-|site-specific-integrase
MSQRYKLYRRTSGIYVVRISVPQRFRRYAGQCEIHTSTGTHDLHEAKQKSALLLAVWYQTLQEYEQLDYRTLSDCAPLLAGEGMISLSNFAQSIELPISQLIREVVNRNLPVFWLATGQFGFYVDEFNAVEREPGAKREKQSDDEKDQPKEVIILNSAFELGIESFANGYLRPFNPRHTLDCLLSAGVSEGEAAFRTSGDNQSGGWFFDLPGVDITADSLLISKVHAEGLRLTWLVKTTPPAVSIHPAVPLVAPVIANEYVHRKHYNENLSWLREEYLKHRRKGKVSEAALRDIRYYFDLMIEVMGDIQLEDFDRDFLRAYESKLRTIPANRNLMKGKHGVKTLDELIAKAAECGDKLMTEESVKKYINSLYGAMEWAVDDGKFLKSPCDNFFPPDDKGEREQDHTDIFEPHEIKAIFSQPWFVAGTVERNAQGRFHQYCPFHYWAPLLGLMTGARVNEIAQLMLDDVLADDGVYYLNLESDSENGKKLKNANSRRKIPVHSTLIELGFIEYVDALKAAGYDRLFPELKPHKTKGYGRPVSAWFNESLLAGRLKLERDRSKSFHSFRHSVSTLLKEKGVSSELRGQLLGHVRGKTETEVRYSKDLKPVHMVEVVEKIDFSLPEIARFNIPDGLDAVRDALRRKRGKQTG
>NZ_CP044143.1|WP_085948178.1|1948190_1949404_-|IS3-family-transposase
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELERENRELRRSNDILRQASAYFAKAEFDRLWKKLMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>NZ_CP044143.1|WP_001046858.1|1947630_1948008_+|DUF4160-domain-containing-protein
MNLDEEFYELQKLFAQKDLLTEKRRSSGGGFMEILLVKRQNMKIKIYQEKGHQLPHIHIDYGKQAHAASYAIQSGDRIEGDLPKKYDSDVSSWLGRNRDKILEIWNALQAGAPYEPLIAELTGGV
>NZ_CP044143.1|WP_001261097.1|1947176_1947509_+|NIPSNAP-family-protein
MRTVEILQYTLRKGSGAAFHAIMQEISVPLHQSHGIDVVSFGNSLDDLDCYYLIRAFDSAKSMTAVLDAFYASADWRSGPREDIIGSIENCIKTVISLPSESVKGLRMQS
>NZ_CP044143.1|WP_000588536.1|1945706_1946174_+|DUF1643-domain-containing-protein
MIKDAIFSPCGKYRYSLSRVWDESKPYTLFIGLNPSYADAEKDDRTLSRCISFAKSWGYGGVYMANLFAFVHTQRHEMMKASDPIGKDNDSHLIRLVSGAGLVVAAWGNEGRHLKRSTTVRQLLPESTMCFVLNATGEPKHPLYMKNDSVLIPLG
>NZ_CP044143.1|WP_000786399.1|1959049_1959493_+|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP044143.1|WP_000416407.1|1959492_1962348_+|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP044143.1|WP_000079623.1|1962402_1963599_-|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFFSCLVFVFFYFAILMTVSADMPLIGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGVWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIVSVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTAYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIMPSLPFL
>NZ_CP044143.1|WP_001059397.1|1963791_1964295_+|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALKAMEEAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCEVRMLREL
>NZ_CP044143.1|WP_000002953.1|1964340_1964757_-|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP044143.1|WP_151121025.1|1964918_1965923_+|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGAHVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKPFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
>NZ_CP044143.1|WP_000036512.1|1965979_1967770_-|hypothetical-protein
MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNNFARNAGGQDNTRNILNPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKFVMNNPEGERADSPKVIIEISLSTITTMGTRQGHTAIIFPQPDGSTNRYERKSFERKDESSLHLITNKVLACYQREANKEIARLLNNHQKLNNLQKLNNLQKLNNLQKLNNLQKLNNIQKLNNIQELNNSQELNNSQELNNSQELNNSQDLKNSQVSCKGSVDFTITDLLEKSLNNALLAIRNEHLLLMPHVCSESISYLLGENGILEEIDKLYELNDHGIDNDKEGNNEINDIMINLSHILIESLDDAKVNLTPVIHSMLMTFLELPYNNDVKILEWCFNKSMQYFDDSAKIEHACSVINHINFRRDQSKVAETLFFNLDKEPYKNSPELQELIWKKLVVYVNDFNLSNREKTYLIQRIFNNVESLFNKVPVSILVNDIFMNDFFMKNTEMINWYFPRLLKSYEDEKIYFDKLGYNFNNKESNEEIMKNQPKDVIEEKLNNELKLRFRMMQTILKSEVNVSPFIDQQRLNTLNPPENLRIAIEKFGWKKKTITA
>NZ_CP044143.1|WP_000583470.1|1967892_1968345_-|DUF386-domain-containing-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP044143.1|WP_000256678.1|1968489_1969083_-|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLVDILRDDRPVGECLAEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARLHPQSAQCVTDFMSTVMSGLSAKAREGHSLEQLCATAALAGEAIKTILKE
>NZ_CP044143.1|WP_000500712.1|1969153_1969867_+|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAERLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA

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Crispr_ID: NZ_CP044143_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_3

3635766-3635854

Unclear

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044143_3

>merge|NZ_CP044143|3|3635766-3635854|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCGCAAAAGCGGGCAGCGAAAAAATTAAAGTCGAGGAGTTCCCCGCGCCAGTGGGGATAAACC

>NZ_CP044143|3|3|3635766-3635854|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACC	GCAAAAGCGGGCAGCGAAAAAATTAAAGTCGAG
GAGTTCCCCGCGCCAGTGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_000581937.1\|3626242_3626491_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP044143.1\|WP_001130278.1\|3645090_3645666_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP044143.1\|WP_000021347.1\|3639589_3640375_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP044143.1\|WP_042909427.1\|3633979_3634600_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP044143.1\|WP_000987944.1\|3647282_3647648_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP044143.1\|WP_001301471.1\|3645933_3647205_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP044143.1\|WP_012779383.1\|3630998_3631913_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP044143.1\|WP_001301644.1\|3643306_3644086_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP044143.1\|WP_001243487.1\|3633291_3633966_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP044143.1\|WP_000211937.1\|3647963_3649763_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP044143.1\|WP_000036723.1\|3629640_3630939_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP044143.1\|WP_000210878.1\|3627915_3629553_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP044143.1\|WP_000109503.1\|3645682_3645943_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP044143.1\|WP_001199973.1\|3634754_3635426_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP044143.1\|WP_000254738.1\|3626490_3626826_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP044143.1\|WP_001164582.1\|3637993_3639271_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP044143.1\|WP_000059304.1\|3640444_3641899_+\|FAD-linked-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP044143.1\|WP_001217990.1\|3631909_3633058_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP044143.1\|WP_001071648.1\|3626896_3627688_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP044143.1\|WP_000039703.1\|3636488_3637967_-\|kinase	unknown	unknown	gnl\|CDD\|212662

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_000581937.1\|3626242_3626491_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP044143.1\|WP_001130278.1\|3645090_3645666_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	1.96043e-88
NZ_CP044143.1\|WP_000021347.1\|3639589_3640375_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.24046e-138
NZ_CP044143.1\|WP_042909427.1\|3633979_3634600_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	2.13345e-77
NZ_CP044143.1\|WP_000987944.1\|3647282_3647648_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
NZ_CP044143.1\|WP_001301471.1\|3645933_3647205_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	4.44674e-126
NZ_CP044143.1\|WP_012779383.1\|3630998_3631913_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.30872e-104
NZ_CP044143.1\|WP_001301644.1\|3643306_3644086_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.2806e-65
NZ_CP044143.1\|WP_001243487.1\|3633291_3633966_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.44494e-83
NZ_CP044143.1\|WP_000211937.1\|3647963_3649763_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP044143.1\|WP_000036723.1\|3629640_3630939_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP044143.1\|WP_000210878.1\|3627915_3629553_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP044143.1\|WP_000109503.1\|3645682_3645943_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	1.18571e-41
NZ_CP044143.1\|WP_001199973.1\|3634754_3635426_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP044143.1\|WP_000254738.1\|3626490_3626826_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP044143.1\|WP_001164582.1\|3637993_3639271_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	7.69151e-30
NZ_CP044143.1\|WP_000059304.1\|3640444_3641899_+\|FAD-linked-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	4.96301e-83
NZ_CP044143.1\|WP_001217990.1\|3631909_3633058_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	5.38776e-66
NZ_CP044143.1\|WP_001071648.1\|3626896_3627688_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP044143.1\|WP_000039703.1\|3636488_3637967_-\|kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	2.7676e-107

>NZ_CP044143.1|WP_001199973.1|3634754_3635426_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP044143.1|WP_042909427.1|3633979_3634600_-|LemA-family-protein
MKRDLNTLRIFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSSHERDVLEAVTLARSQANRASSDLQQTPGDEQKLQAWQQAQAQVTRTLGQLTIISERYPELKSQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNANAH
>NZ_CP044143.1|WP_001243487.1|3633291_3633966_-|YgcG-family-protein
MRNFIFLMAFFCSSVFATQIPVPESPKYVNDLTGTLTNSEVNTLTNQIKALTQKNYAQLVVLVVETTGDETIEQYATRVFDSWKPGDKDRDDGVLLLVAWQDHTVRIEIGYGLEGIITDAQSGKIIRNSIIPAFKKGDLAGGLQKGISDIESRLTGNNLATITPTDHPLPFSGWWALLVWAIVLTFISARGYIKTLGVICFAAIVLAFVLPIAGFSGSWGVLAT
>NZ_CP044143.1|WP_001217990.1|3631909_3633058_-|YgcG-family-protein
MRIFLLLLMLCGFQVFAERLPSVTDLTGTLTTEEQTALTQQLQTLEQQNHFQVAVLVTPTTGGKNIKLAASQRYGVYHWKPVGEKRYGEGILILVVWPEGLASMKIGHGLEEMLPPEQAAQIVRYHMQPEFEKNNLFAGLTGGIESIAQFTHIKANLSPLDALANHLFANPQRSLPCLAWTLLMIVAIVVLWLFASRPRRGIWMISMITPMVWFFSFQDDVIIRRVSVVCFSLLLATTCKQRLAVVFNMCRVFPMMLTPKNKNAKVKKQKKTPQVRESGRNSLFVVMLIIIVGWCLVFASNKDIAFISTIIGLIDHFIGPITIAGIVLLIIVAKFTGNLKLGSGEKSNRKTGNRNAHSRSSSRNSFRGGGGSSGGGGSSVRW
>NZ_CP044143.1|WP_012779383.1|3630998_3631913_-|YgcG-family-protein
MIVMRLIFILFTLWCLPGLAQQIAVPELRQQVTDITGTLSTSEQQSLTQQLQDITHKTRAQVAVLVVPSTGDDSIEQYATRVFDSWKLGDKQRNDGILLLVAWEDHAVRIEVGYGLEGVVTDLQAAKIIRDILIPAFKSDDLMGGLTLASENIGALLLNGELPEDRGDYYSINPPIPLSLAVIILLAVLSYFIVFTDPSNLPWITLTGAIYGMVFLYVAEPGPWTNLIVACGMLTPFAIVPLVIFWLIVNKKLRAKYKKLSKDRASRKGSSSSSSGGGSSGGGSGGGFSGGGGSSGGGGASGRW
>NZ_CP044143.1|WP_000036723.1|3629640_3630939_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP044143.1|WP_000210878.1|3627915_3629553_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP044143.1|WP_001071648.1|3626896_3627688_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP044143.1|WP_000254738.1|3626490_3626826_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP044143.1|WP_000581937.1|3626242_3626491_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP044143.1|WP_000039703.1|3636488_3637967_-|kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGQITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLSTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKALTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>NZ_CP044143.1|WP_001164582.1|3637993_3639271_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTQPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP044143.1|WP_000021347.1|3639589_3640375_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASQASNYVNGHLLVVDGGYLVR
>NZ_CP044143.1|WP_000059304.1|3640444_3641899_+|FAD-linked-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP044143.1|WP_001301644.1|3643306_3644086_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAHGNSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFASEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTEHGLRCCRIRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAELPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP044143.1|WP_001130278.1|3645090_3645666_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISQIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP044143.1|WP_000109503.1|3645682_3645943_-|ferredoxin-family-protein
MSVARNLWRAADAPHIVPADSVERQMVQRLINACPVGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP044143.1|WP_001301471.1|3645933_3647205_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLLWRHLRRHGLWNLAGDVIRSVRCL
>NZ_CP044143.1|WP_000987944.1|3647282_3647648_-|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP044143.1|WP_000211937.1|3647963_3649763_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGVVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQEEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY

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Crispr_ID: NZ_CP044143_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_4

3661545-3661757

TypeI-E

I-E

Consensus_repeat	Method
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP044143_4

>merge|NZ_CP044143|4|3661545-3661757|PILER-CR,CRT,CRISPRCasFinder
TGTGTTCCCCGCGCCAGCGGGGATAAACCGTCACCAAAACAGTGACAAAAACTGTCACCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCTCATATTCGGATTGATCGTGTGTTTCGGTTTGTGTTCCCCGCGCCAGCGGGGATAAACCGGCCCAGGGATTTGTTCAATCCAGCGTGCCGCTGTGTTCCCCGCATCAGCGGGGATAAACCG

>NZ_CP044143|4|1|3661545-3661696|PILER-CR
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACCAAAACAGTGACAAAAACTGTCACCAA
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCATATTCGGATTGATCGTGTGTTTCGGTT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP044143|4|1|3661545-3661757|CRT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACCAAAACAGTGACAAAAACTGTCACCAA
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCATATTCGGATTGATCGTGTGTTTCGGTT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCCAGGGATTTGTTCAATCCAGCGTGCCGC
TGTGTTCCCCGCATCAGCGGGGATAAACCG

>NZ_CP044143|4|4|3661546-3661757|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCACCAAAACAGTGACAAAAACTGTCACCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCATATTCGGATTGATCGTGTGTTTCGGTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCCCAGGGATTTGTTCAATCCAGCGTGCCGCT
GTGTTCCCCGCATCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_001084082.1\|3655687_3657250_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP044143.1\|WP_000372111.1\|3663127_3664036_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP044143.1\|WP_001173673.1\|3665464_3666070_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP044143.1\|WP_000246158.1\|3666966_3667677_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP044143.1\|WP_001090366.1\|3664037_3665465_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP044143.1\|WP_000490413.1\|3661838_3662876_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP044143.1\|WP_000039864.1\|3651548_3652283_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP044143.1\|WP_001233978.1\|3652890_3655590_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP044143.1\|WP_001295182.1\|3669182_3669944_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP044143.1\|WP_000517476.1\|3666636_3666948_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP044143.1\|WP_000956458.1\|3652546_3652699_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP044143.1\|WP_000085058.1\|3658860_3659607_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP044143.1\|WP_001246103.1\|3666119_3666443_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP044143.1\|WP_000029325.1\|3657246_3657783_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP044143.1\|WP_000281463.1\|3659588_3660239_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP044143.1\|WP_001219242.1\|3667676_3668156_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP044143.1\|WP_000206445.1\|3657794_3658850_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP044143.1\|WP_000144847.1\|3660235_3661159_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP044143.1\|WP_000063176.1\|3661155_3661449_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP044143.1\|WP_000568934.1\|3668152_3669202_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_001084082.1\|3655687_3657250_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP044143.1\|WP_000372111.1\|3663127_3664036_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP044143.1\|WP_001173673.1\|3665464_3666070_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP044143.1\|WP_000246158.1\|3666966_3667677_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	6.38982e-120
NZ_CP044143.1\|WP_001090366.1\|3664037_3665465_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP044143.1\|WP_000490413.1\|3661838_3662876_-\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP044143.1\|WP_000039864.1\|3651548_3652283_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	5.85899e-137
NZ_CP044143.1\|WP_001233978.1\|3652890_3655590_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP044143.1\|WP_001295182.1\|3669182_3669944_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP044143.1\|WP_000517476.1\|3666636_3666948_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP044143.1\|WP_000956458.1\|3652546_3652699_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP044143.1\|WP_000085058.1\|3658860_3659607_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.00414e-48
NZ_CP044143.1\|WP_001246103.1\|3666119_3666443_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	3.44794e-52
NZ_CP044143.1\|WP_000029325.1\|3657246_3657783_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	3.2742e-30
NZ_CP044143.1\|WP_000281463.1\|3659588_3660239_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.5854e-93
NZ_CP044143.1\|WP_001219242.1\|3667676_3668156_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP044143.1\|WP_000206445.1\|3657794_3658850_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.45802e-155
NZ_CP044143.1\|WP_000144847.1\|3660235_3661159_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.06391e-157
NZ_CP044143.1\|WP_000063176.1\|3661155_3661449_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP044143.1\|WP_000568934.1\|3668152_3669202_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0

>NZ_CP044143.1|WP_000063176.1|3661155_3661449_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP044143.1|WP_000144847.1|3660235_3661159_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEKVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP044143.1|WP_000281463.1|3659588_3660239_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRSFVPELRTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEV
>NZ_CP044143.1|WP_000085058.1|3658860_3659607_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSAPDLLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>NZ_CP044143.1|WP_000206445.1|3657794_3658850_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP044143.1|WP_000029325.1|3657246_3657783_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAALSANVKAIDERLPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRVVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRHQRPTEFIRIRWALEYYQAGDVDNEQNQ
>NZ_CP044143.1|WP_001084082.1|3655687_3657250_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHPFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLERVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP044143.1|WP_001233978.1|3652890_3655590_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKEGGDGYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLAPELKIPEGSRKNYEKISHSTLGYWLWNYYLSECEELLPSSSLSSRKLTRVIEMWMSITTGHHGRPPDRIDELDNFLPEDKAAARDFLLEIKALFPLIEIPTFWDDDEGVELLKQLSWYISATVVLADWTGSSTRFFPRVAHPMDIKDYWQKTLVQAQNALTVFPPKAETAPFTGINTLFPFIEHPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAARKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFANSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIEMETLARFGKEDGSQRAGKVLICTQVLEQSVDCDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFKPGYAANINDYLPEKLSTRLAEESVSLWLATCIAGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQDPEMANVILVTDDESCGYSAREGLIGKVD
>NZ_CP044143.1|WP_000956458.1|3652546_3652699_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP044143.1|WP_000039864.1|3651548_3652283_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKNGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP044143.1|WP_000490413.1|3661838_3662876_-|aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPQSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP044143.1|WP_000372111.1|3663127_3664036_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHQNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP044143.1|WP_001090366.1|3664037_3665465_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRSRVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGEK
>NZ_CP044143.1|WP_001173673.1|3665464_3666070_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP044143.1|WP_001246103.1|3666119_3666443_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLMTVGIMFGALFMWLLG
>NZ_CP044143.1|WP_000517476.1|3666636_3666948_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP044143.1|WP_000246158.1|3666966_3667677_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVYALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGAAITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP044143.1|WP_001219242.1|3667676_3668156_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP044143.1|WP_000568934.1|3668152_3669202_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP044143.1|WP_001295182.1|3669182_3669944_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP044143_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_5

4188162-4188267

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATTAGGCGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044143_5

>merge|NZ_CP044143|5|4188162-4188267|CRISPRCasFinder
CCGAGCCGTAGGCCGGATTAGGCGTTCACGCCGCATCCTGTGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTT

>NZ_CP044143|5|5|4188162-4188267|CRISPRCasFinder
CCGAGCCGTAGGCCGGATTAGGCGTT	CACGCCGCATCCTGTGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_000332037.1\|4186934_4188065_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	unknown	unknown	gnl\|CDD\|181647
NZ_CP044143.1\|WP_001225855.1\|4207310_4208087_+\|YfaP-family-protein	unknown	unknown	gnl\|CDD\|227021
NZ_CP044143.1\|WP_021502145.1\|4201261_4205656_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP044143.1\|WP_000779084.1\|4180841_4181918_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
NZ_CP044143.1\|WP_000176738.1\|4183675_4184554_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176102
NZ_CP044143.1\|WP_000948724.1\|4179478_4180837_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
NZ_CP044143.1\|WP_000301028.1\|4185976_4186627_+\|lipopolysaccharide-kinase-InaA	unknown	unknown	gnl\|CDD\|182136
NZ_CP044143.1\|WP_000660231.1\|4184705_4185896_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP044143.1\|WP_001301786.1\|4182141_4183212_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044143.1\|WP_001061917.1\|4211410_4212061_-\|transcriptional-regulator-RcsB	unknown	unknown	gnl\|CDD\|182771
NZ_CP044143.1\|WP_000876002.1\|4208361_4211211_+\|two-component-system-sensor-histidine-kinase-RcsC	unknown	unknown	gnl\|CDD\|182772
NZ_CP044143.1\|WP_000990779.1\|4195165_4195888_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
NZ_CP044143.1\|WP_001209872.1\|4176328_4177588_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	unknown	unknown	gnl\|CDD\|225617
NZ_CP044143.1\|WP_000857257.1\|4177577_4179206_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
NZ_CP044143.1\|WP_001075170.1\|4188291_4190577_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
NZ_CP044143.1\|WP_001295211.1\|4200494_4201118_+\|DUF1175-domain-containing-protein	unknown	unknown	gnl\|CDD\|225774
NZ_CP044143.1\|WP_000135039.1\|4186680_4186935_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	unknown	unknown	gnl\|CDD\|182668
NZ_CP044143.1\|WP_042355394.1\|4198869_4200498_+\|DUF2138-domain-containing-protein	unknown	unknown	gnl\|CDD\|227030
NZ_CP044143.1\|WP_001263828.1\|4191272_4195025_+\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	unknown	unknown	gnl\|CDD\|182059
NZ_CP044143.1\|WP_001281251.1\|4196034_4198662_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_000332037.1\|4186934_4188065_-\|ribonucleoside-diphosphate-reductase-1-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
NZ_CP044143.1\|WP_001225855.1\|4207310_4208087_+\|YfaP-family-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	3.30839e-153
NZ_CP044143.1\|WP_000779084.1\|4180841_4181918_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
NZ_CP044143.1\|WP_000176738.1\|4183675_4184554_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176102	cd05466, PBP2_LTTR_substrate, The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily. This model and hierarchy represent the the substrate-binding domain of the LysR-type transcriptional regulators that form the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, oxidative stress responses, nodule formation of nitrogen-fixing bacteria, synthesis of virulence factors, toxin production, attachment and secretion, to name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.9401e-45
NZ_CP044143.1\|WP_000948724.1\|4179478_4180837_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
NZ_CP044143.1\|WP_000301028.1\|4185976_4186627_+\|lipopolysaccharide-kinase-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	4.41923e-159
NZ_CP044143.1\|WP_000660231.1\|4184705_4185896_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.20553e-100
NZ_CP044143.1\|WP_021502145.1\|4201261_4205656_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP044143.1\|WP_001061917.1\|4211410_4212061_-\|transcriptional-regulator-RcsB	gnl\|CDD\|182771	PRK10840, PRK10840, transcriptional regulator RcsB; Provisional.	2.27775e-154
NZ_CP044143.1\|WP_000876002.1\|4208361_4211211_+\|two-component-system-sensor-histidine-kinase-RcsC	gnl\|CDD\|182772	PRK10841, PRK10841, two-component system sensor histidine kinase RcsC.	0
NZ_CP044143.1\|WP_000990779.1\|4195165_4195888_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.1677e-171
NZ_CP044143.1\|WP_001209872.1\|4176328_4177588_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP044143.1\|WP_000857257.1\|4177577_4179206_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
NZ_CP044143.1\|WP_001075170.1\|4188291_4190577_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
NZ_CP044143.1\|WP_001295211.1\|4200494_4201118_+\|DUF1175-domain-containing-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	7.99004e-141
NZ_CP044143.1\|WP_000135039.1\|4186680_4186935_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	1.23742e-52
NZ_CP044143.1\|WP_042355394.1\|4198869_4200498_+\|DUF2138-domain-containing-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_CP044143.1\|WP_001263828.1\|4191272_4195025_+\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
NZ_CP044143.1\|WP_001281251.1\|4196034_4198662_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0

>NZ_CP044143.1|WP_000332037.1|4186934_4188065_-|ribonucleoside-diphosphate-reductase-1-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>NZ_CP044143.1|WP_000135039.1|4186680_4186935_-|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEL
>NZ_CP044143.1|WP_000301028.1|4185976_4186627_+|lipopolysaccharide-kinase-InaA
MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVTPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>NZ_CP044143.1|WP_000660231.1|4184705_4185896_+|MFS-transporter
MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLHASPDKAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILVLSSLAFLVVTALYPFCHSIESLLFIRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWEAFNMAFWLCTGVAAVGIILSLIMTVPPVISHADGSKPKMGFAAMFDRAALPFAMVTFFMTFSYAGVSAFLALYARELNLMSAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYPCLLFFTVGLVVLGYTQGSVMMVVSGALIGIGYGSVTPVFQTQIISSVEPHKIGVANSLFFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVALVVAKEIH
>NZ_CP044143.1|WP_000176738.1|4183675_4184554_-|LysR-family-transcriptional-regulator
MTLTQINSLLAVLDYGGFTEASKRLFMTQSAVSQAIAALEQELGVNILLRDRRKAIQLTTAGHRIVQHLRAINREVNAVKEIAEQEKQNPQRTLRLGCFPSVCACILPVVIRYFEIHHPNIKIIPFEENSTAIIDSLQNESIDAGFVHFPVSGMYSVPIYQDKFTVVLPPNHALAKNSTITVEELMGEPLIISKGRYELSIMALFKEKNITPQIKYEFNHPDTAISFIRQGLGIALLPELTLKTIADELCSVPLEPTFYRQISLLAKEKPVEGSPLFLLQMCTEQLVVSGKI
>NZ_CP044143.1|WP_001301786.1|4182141_4183212_-|hypothetical-protein
MPNTSIHLSRCNILQNNKLQPTEIYKESQQTAKLEFFCDEFLKISQSRYGLSTSTDSIANLLAFFTKASDAIDSIKTQKIDVHSYGFVPIRHFVEHVITYKNEFAADYEPYTLTFTRGENNEGILSVESKEGFISQRTINLNEYETAINIINEHVIKENIHNTVQSPTEKYISKINSSDKPYKTSSKESIKSQLYSDQRNIQTCYYILRKNTEWYKYASSEERYDKFKNSSKEIKNTYKQIVQAQKKLNQMKYINKLSGELIDITDKKLAPLINDSFSYTRDFFAYSKQEKNIFTFDNSKFVDPKEKEGLMVQHSNGQLVITGKYCPEGVQTAFTQEQYDKLIRYINIFFTFPKLE
>NZ_CP044143.1|WP_000779084.1|4180841_4181918_+|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>NZ_CP044143.1|WP_000948724.1|4179478_4180837_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRNGG
>NZ_CP044143.1|WP_000857257.1|4177577_4179206_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>NZ_CP044143.1|WP_001209872.1|4176328_4177588_-|glycerol-3-phosphate-dehydrogenase-subunit-GlpB
MRFDTIIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQAVTDIHSGLESLRQQAPAHPYSLLGPQRVLDLACQAQALIAESGAQLQGSVELPHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDQTLRPSQAGQTIENLFTIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>NZ_CP044143.1|WP_001075170.1|4188291_4190577_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>NZ_CP044143.1|WP_001263828.1|4191272_4195025_+|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC
MRVIFLRKEYLSLLPSMIASLFSANGVAAAIDLCQGYDIKASCHASRQSLSGITQVWSIADGQWLVFSDMTNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNAVFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFAHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAADLAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>NZ_CP044143.1|WP_000990779.1|4195165_4195888_-|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLSYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>NZ_CP044143.1|WP_001281251.1|4196034_4198662_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVEGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>NZ_CP044143.1|WP_042355394.1|4198869_4200498_+|DUF2138-domain-containing-protein
MALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETIPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIASDLLSGKKRWQASFGLEERAAEKTPVRQRIVASARLLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPIIWQPL
>NZ_CP044143.1|WP_001295211.1|4200494_4201118_+|DUF1175-domain-containing-protein
MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>NZ_CP044143.1|WP_021502145.1|4201261_4205656_+|alpha-2-macroglobulin-family-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVDVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGDLPSGGKSFTVNFDKPGNYNLTLRDKDGLILAGLSHAVSGKGSMSHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPSAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLAQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAVNSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNWLAKYMATMPSVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREAAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>NZ_CP044143.1|WP_001225855.1|4207310_4208087_+|YfaP-family-protein
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>NZ_CP044143.1|WP_000876002.1|4208361_4211211_+|two-component-system-sensor-histidine-kinase-RcsC
MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQRESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAFEPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGLRDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANRLQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKADPRWMQERSWFGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLARMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLNMLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRVKMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDFSKIESEQLMIEPREFSPREVMNHITANYLPLVVRKQLGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGSQFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQEPTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARIYLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES
>NZ_CP044143.1|WP_001061917.1|4211410_4212061_-|transcriptional-regulator-RcsB
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD

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Crispr_ID: NZ_CP044143_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_6

4696541-4696690

Orphan

Consensus_repeat	Method
TACCAGAGATAGCGAACCGTAGGTCGGAAAAGGCGCTCGCGCCGCATCCGACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044143_6

>merge|NZ_CP044143|6|4696541-4696690|CRISPRCasFinder
TACCAGAGATAGCGAACCGTAGGTCGGAAAAGGCGCTCGCGCCGCATCCGACATTGGCAGTGTGCCTGATGCGACGCTGTTCGCGTCTTACCAGGCCTACCAGAGATAGCGAACCGTAGGTCGGATAAGGCGCTCGCGCCGCATCCGACA

>NZ_CP044143|6|6|4696541-4696690|CRISPRCasFinder
TACCAGAGATAGCGAACCGTAGGTCGGAAAAGGCGCTCGCGCCGCATCCGACA	TTGGCAGTGTGCCTGATGCGACGCTGTTCGCGTCTTACCAGGCC
TACCAGAGATAGCGAACCGTAGGTCGGATAAGGCGCTCGCGCCGCATCCGACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_001024949.1\|4693955_4694558_-\|YebB-family-permuted-papain-like-enzyme	unknown	unknown	gnl\|CDD\|183152
NZ_CP044143.1\|WP_000448391.1\|4700714_4701686_+\|lauroyl-Kdo(2)-lipid-IV(A)-myristoyltransferase	unknown	unknown	gnl\|CDD\|236355
NZ_CP044143.1\|WP_001056694.1\|4703386_4704256_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|183082
NZ_CP044143.1\|WP_000580323.1\|4694832_4695444_+\|Holliday-junction-branch-migration-protein-RuvA	unknown	unknown	gnl\|CDD\|234645
NZ_CP044143.1\|WP_001184045.1\|4699272_4700595_+\|murein-DD-endopeptidase-MepM	unknown	unknown	gnl\|CDD\|236946
NZ_CP044143.1\|WP_001303192.1\|4698324_4699257_+\|zinc-ABC-transporter-substrate-binding-protein-ZnuA	unknown	unknown	gnl\|CDD\|236558
NZ_CP044143.1\|WP_000091169.1\|4701816_4703259_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_CP044143.1\|WP_000891621.1\|4689410_4689977_-\|hydrolase	unknown	unknown	gnl\|CDD\|183137
NZ_CP044143.1\|WP_000907234.1\|4692657_4693398_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234640
NZ_CP044143.1\|WP_000301737.1\|4704593_4706069_+\|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235579
NZ_CP044143.1\|WP_000252980.1\|4688148_4688544_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226311
NZ_CP044143.1\|WP_000800512.1\|4708151_4708793_+\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl\|CDD\|235577
NZ_CP044143.1\|WP_000202996.1\|4697490_4698246_-\|zinc-ABC-transporter-ATP-binding-protein-ZnuC	unknown	unknown	gnl\|CDD\|181939
NZ_CP044143.1\|WP_001295503.1\|4693432_4693954_+\|crossover-junction-endodeoxyribonuclease-RuvC	unknown	unknown	gnl\|CDD\|129331
NZ_CP044143.1\|WP_000568519.1\|4695452_4696463_+\|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl\|CDD\|234619
NZ_CP044143.1\|WP_001258683.1\|4690286_4692059_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP044143.1\|WP_010723105.1\|4694628_4694694_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044143.1\|WP_001300367.1\|4692176_4692629_+\|dihydroneopterin-triphosphate-diphosphatase	unknown	unknown	gnl\|CDD\|236516
NZ_CP044143.1\|WP_000571476.1\|4696708_4697494_-\|zinc-ABC-transporter-permease-subunit-ZnuB	unknown	unknown	gnl\|CDD\|181938
NZ_CP044143.1\|WP_001069467.1\|4706303_4708115_+\|phosphogluconate-dehydratase	unknown	unknown	gnl\|CDD\|181628

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_001024949.1\|4693955_4694558_-\|YebB-family-permuted-papain-like-enzyme	gnl\|CDD\|183152	PRK11470, PRK11470, YebB family permuted papain-like enzyme.	5.39625e-135
NZ_CP044143.1\|WP_000448391.1\|4700714_4701686_+\|lauroyl-Kdo(2)-lipid-IV(A)-myristoyltransferase	gnl\|CDD\|236355	PRK08943, PRK08943, lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated.	0
NZ_CP044143.1\|WP_001056694.1\|4703386_4704256_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|183082	PRK11302, PRK11302, DNA-binding transcriptional regulator HexR; Provisional.	0
NZ_CP044143.1\|WP_000202996.1\|4697490_4698246_-\|zinc-ABC-transporter-ATP-binding-protein-ZnuC	gnl\|CDD\|181939	PRK09544, znuC, high-affinity zinc transporter ATPase; Reviewed.	0
NZ_CP044143.1\|WP_001184045.1\|4699272_4700595_+\|murein-DD-endopeptidase-MepM	gnl\|CDD\|236946	PRK11649, PRK11649, putative peptidase; Provisional.	0
NZ_CP044143.1\|WP_001303192.1\|4698324_4699257_+\|zinc-ABC-transporter-substrate-binding-protein-ZnuA	gnl\|CDD\|236558	PRK09545, znuA, zinc ABC transporter substrate-binding protein ZnuA.	0
NZ_CP044143.1\|WP_000091169.1\|4701816_4703259_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_CP044143.1\|WP_000891621.1\|4689410_4689977_-\|hydrolase	gnl\|CDD\|183137	PRK11440, PRK11440, putative hydrolase; Provisional.	4.9839e-137
NZ_CP044143.1\|WP_000907234.1\|4692657_4693398_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|234640	PRK00110, PRK00110, YebC/PmpR family DNA-binding transcriptional regulator.	4.59796e-164
NZ_CP044143.1\|WP_000301737.1\|4704593_4706069_+\|glucose-6-phosphate-dehydrogenase	gnl\|CDD\|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NZ_CP044143.1\|WP_000252980.1\|4688148_4688544_-\|hypothetical-protein	gnl\|CDD\|226311	COG3788, COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only].	2.75583e-65
NZ_CP044143.1\|WP_000800512.1\|4708151_4708793_+\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl\|CDD\|235577	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	4.22426e-135
NZ_CP044143.1\|WP_001295503.1\|4693432_4693954_+\|crossover-junction-endodeoxyribonuclease-RuvC	gnl\|CDD\|129331	TIGR00228, Crossover_junction_endodeoxyribonuclease_RuvC, crossover junction endodeoxyribonuclease RuvC. Endonuclease that resolves Holliday junction intermediates in genetic recombination. The active form of the protein is a dimer. Structure studies reveals that the catalytic center, comprised of four acidic residues, lies at the bottom of a cleft that fits a DNA duplex. The model hits a single Synechocystis PCC6803 protein at a score of 30, below the trusted cutoff, that appears orthologous and may act as authentic RuvC. [DNA metabolism, DNA replication, recombination, and repair].	1.05967e-94
NZ_CP044143.1\|WP_000568519.1\|4695452_4696463_+\|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl\|CDD\|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
NZ_CP044143.1\|WP_001258683.1\|4690286_4692059_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP044143.1\|WP_000580323.1\|4694832_4695444_+\|Holliday-junction-branch-migration-protein-RuvA	gnl\|CDD\|234645	PRK00116, ruvA, Holliday junction branch migration protein RuvA.	7.87495e-104
NZ_CP044143.1\|WP_001300367.1\|4692176_4692629_+\|dihydroneopterin-triphosphate-diphosphatase	gnl\|CDD\|236516	PRK09438, nudB, dihydroneopterin triphosphate pyrophosphatase; Provisional.	2.13728e-99
NZ_CP044143.1\|WP_000571476.1\|4696708_4697494_-\|zinc-ABC-transporter-permease-subunit-ZnuB	gnl\|CDD\|181938	PRK09543, znuB, zinc ABC transporter permease subunit ZnuB.	2.64509e-163
NZ_CP044143.1\|WP_001069467.1\|4706303_4708115_+\|phosphogluconate-dehydratase	gnl\|CDD\|181628	PRK09054, PRK09054, phosphogluconate dehydratase; Validated.	0

>NZ_CP044143.1|WP_000568519.1|4695452_4696463_+|Holliday-junction-branch-migration-DNA-helicase-RuvB
MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPEMP
>NZ_CP044143.1|WP_000580323.1|4694832_4695444_+|Holliday-junction-branch-migration-protein-RuvA
MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
>NZ_CP044143.1|WP_010723105.1|4694628_4694694_+|hypothetical-protein
MYIFITHFFTEYVILKYLLPI
>NZ_CP044143.1|WP_001024949.1|4693955_4694558_-|YebB-family-permuted-papain-like-enzyme
MNINYPAEYEIGDKVFTCIGAALFGQISAASNCWSNHVGIIIGHNGEDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKRLDAGLTEQQKQRIVEQVPSRLRKLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFLGSIPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV
>NZ_CP044143.1|WP_001295503.1|4693432_4693954_+|crossover-junction-endodeoxyribonuclease-RuvC
MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
>NZ_CP044143.1|WP_000907234.1|4692657_4693398_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPDANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAEDVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHNGEISDEVAATL
>NZ_CP044143.1|WP_001300367.1|4692176_4692629_+|dihydroneopterin-triphosphate-diphosphatase
MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVEEGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA
>NZ_CP044143.1|WP_001258683.1|4690286_4692059_+|aspartate--tRNA-ligase
MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLRSVEFAVFAGPANDPKGRVAALCVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPAALAELSIQVVKKAENN
>NZ_CP044143.1|WP_000891621.1|4689410_4689977_-|hydrolase
MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKFRASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKRQWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAASAEQHNNSINHIYPRIARVRSVEEILNAL
>NZ_CP044143.1|WP_000252980.1|4688148_4688544_-|hypothetical-protein
MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAIRIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRSGMSATWCALLLMVLANLWYMPWELVFSLR
>NZ_CP044143.1|WP_000571476.1|4696708_4697494_-|zinc-ABC-transporter-permease-subunit-ZnuB
MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVSLMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFVDGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVLVGMVAVTDGLTFSAFYDTPAGPSVVLCAALLFIISMMKKQAS
>NZ_CP044143.1|WP_000202996.1|4697490_4698246_-|zinc-ABC-transporter-ATP-binding-protein-ZnuC
MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDILPALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFGPRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS
>NZ_CP044143.1|WP_001303192.1|4698324_4699257_+|zinc-ABC-transporter-substrate-binding-protein-ZnuA
MLHKKTLLFAALFAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQVTIAQLEDVKPLLMKSINGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHGKLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD
>NZ_CP044143.1|WP_001184045.1|4699272_4700595_+|murein-DD-endopeptidase-MepM
MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRDATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVSTGDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRETRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQWQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRNGTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGEVVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGPHLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD
>NZ_CP044143.1|WP_000448391.1|4700714_4701686_+|lauroyl-Kdo(2)-lipid-IV(A)-myristoyltransferase
METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFRDPILARLGRIAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAELAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAMFHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSEFVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHTIARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK
>NZ_CP044143.1|WP_000091169.1|4701816_4703259_-|pyruvate-kinase
MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGINYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGDVMSTVGSTNTTRILTVE
>NZ_CP044143.1|WP_001056694.1|4703386_4704256_-|MurR/RpiR-family-transcriptional-regulator
MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAALALEANVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESAMATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYSDDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLAREATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDKQLLNLSDDR
>NZ_CP044143.1|WP_000301737.1|4704593_4706069_+|glucose-6-phosphate-dehydrogenase
MAVTQTAQVCDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTRIIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRLGAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEINDQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVGIEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDRSNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFYLRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPGLDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVDSITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE
>NZ_CP044143.1|WP_001069467.1|4706303_4708115_+|phosphogluconate-dehydratase
MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGNLAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVGQVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPGLTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAPGTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWMPIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMARLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGELDWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVVFESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVTDGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAAREPHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF
>NZ_CP044143.1|WP_000800512.1|4708151_4708793_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVLEVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLKAATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCPTGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL

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Crispr_ID: NZ_CP044143_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044143_7

4896460-4896583

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044143_7

>merge|NZ_CP044143|7|4896460-4896583|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP044143|7|7|4896460-4896583|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044143.1\|WP_001182346.1\|4901902_4903114_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP044143.1\|WP_000102278.1\|4905479_4905569_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP044143.1\|WP_001412436.1\|4892011_4892680_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP044143.1\|WP_000007283.1\|4907049_4907631_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP044143.1\|WP_000528342.1\|4887882_4888092_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP044143.1\|WP_000534285.1\|4896897_4898154_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP044143.1\|WP_001070230.1\|4888547_4889174_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP044143.1\|WP_001174945.1\|4898194_4899568_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP044143.1\|WP_000493949.1\|4899782_4900424_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP044143.1\|WP_000587574.1\|4893465_4894278_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP044143.1\|WP_000716940.1\|4894289_4895894_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP044143.1\|WP_000212652.1\|4896019_4896325_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP044143.1\|WP_000190982.1\|4904155_4905181_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP044143.1\|WP_000269501.1\|4903226_4904159_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP044143.1\|WP_000701046.1\|4905734_4906904_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP044143.1\|WP_001295403.1\|4885913_4887326_-\|pyruvate-kinase-I	unknown	unknown	gnl\|CDD\|181699
NZ_CP044143.1\|WP_000517585.1\|4891300_4891948_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP044143.1\|WP_001069991.1\|4892676_4893462_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP044143.1\|WP_000098902.1\|4900463_4901612_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP044143.1\|WP_000181307.1\|4889194_4891297_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629

Protein	Function_ID	Function_description	E-value
NZ_CP044143.1\|WP_001182346.1\|4901902_4903114_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP044143.1\|WP_001412436.1\|4892011_4892680_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	5.84654e-75
NZ_CP044143.1\|WP_000007283.1\|4907049_4907631_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP044143.1\|WP_000528342.1\|4887882_4888092_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP044143.1\|WP_000534285.1\|4896897_4898154_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP044143.1\|WP_001070230.1\|4888547_4889174_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP044143.1\|WP_001174945.1\|4898194_4899568_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP044143.1\|WP_000493949.1\|4899782_4900424_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	4.10481e-123
NZ_CP044143.1\|WP_000587574.1\|4893465_4894278_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	5.65445e-174
NZ_CP044143.1\|WP_000716940.1\|4894289_4895894_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP044143.1\|WP_000212652.1\|4896019_4896325_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	5.72726e-63
NZ_CP044143.1\|WP_000190982.1\|4904155_4905181_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP044143.1\|WP_000269501.1\|4903226_4904159_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP044143.1\|WP_000701046.1\|4905734_4906904_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.05036e-98
NZ_CP044143.1\|WP_001295403.1\|4885913_4887326_-\|pyruvate-kinase-I	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP044143.1\|WP_000517585.1\|4891300_4891948_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	7.38894e-124
NZ_CP044143.1\|WP_001069991.1\|4892676_4893462_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	4.74994e-163
NZ_CP044143.1\|WP_000098902.1\|4900463_4901612_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP044143.1\|WP_000181307.1\|4889194_4891297_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0

>NZ_CP044143.1|WP_000212652.1|4896019_4896325_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTAQLKKLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP044143.1|WP_000716940.1|4894289_4895894_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARKQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEYGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDQFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP044143.1|WP_000587574.1|4893465_4894278_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERAFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGKRCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>NZ_CP044143.1|WP_001069991.1|4892676_4893462_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGERIYLYSKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINGVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP044143.1|WP_001412436.1|4892011_4892680_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHAPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP044143.1|WP_000517585.1|4891300_4891948_+|YdhW-family-putative-oxidoreductase-system-protein
MGKMNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSVAGQLVARAVFLSPPYSVAEEELSVLLENIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP044143.1|WP_000181307.1|4889194_4891297_+|aldehyde-ferredoxin-oxidoreductase
MTNGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAECWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>NZ_CP044143.1|WP_001070230.1|4888547_4889174_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP044143.1|WP_000528342.1|4887882_4888092_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP044143.1|WP_001295403.1|4885913_4887326_-|pyruvate-kinase-I
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP044143.1|WP_000534285.1|4896897_4898154_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKANDTLLADGTMNNLGGEDSDTIVENGAIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRASVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFSIGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVNGDIRVQITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP044143.1|WP_001174945.1|4898194_4899568_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRYLQRLPSAIILQRASR
>NZ_CP044143.1|WP_000493949.1|4899782_4900424_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQSGTEA
>NZ_CP044143.1|WP_000098902.1|4900463_4901612_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFTVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFVAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP044143.1|WP_001182346.1|4901902_4903114_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAAMLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>NZ_CP044143.1|WP_000269501.1|4903226_4904159_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP044143.1|WP_000190982.1|4904155_4905181_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP044143.1|WP_000102278.1|4905479_4905569_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP044143.1|WP_000701046.1|4905734_4906904_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNKFGAAISMAVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP044143.1|WP_000007283.1|4907049_4907631_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP044143_4	4.1\|3661575\|31\|NZ_CP044143\|PILER-CR,CRT	3661575-3661605	31	MK047640	Phage NV18, complete genome	15646-15676	1	0.968
NZ_CP044143_4	4.4\|3661575\|32\|NZ_CP044143\|CRISPRCasFinder	3661575-3661606	32	MK047640	Phage NV18, complete genome	15645-15676	1	0.969
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101196-101230	2	0.943
NZ_CP044143_4	4.1\|3661575\|31\|NZ_CP044143\|PILER-CR,CRT	3661575-3661605	31	MF417881	Uncultured Caudovirales phage clone 7AX_3, partial genome	2718-2748	2	0.935
NZ_CP044143_4	4.4\|3661575\|32\|NZ_CP044143\|CRISPRCasFinder	3661575-3661606	32	MF417881	Uncultured Caudovirales phage clone 7AX_3, partial genome	2718-2749	2	0.938
NZ_CP044143_7	7.1\|4896503\|38\|NZ_CP044143\|CRISPRCasFinder	4896503-4896540	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	165464-165498	3	0.914
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	14239-14273	5	0.857
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	56080-56114	5	0.857
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	6804-6838	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208981-209015	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219475-219509	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210309-210343	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191264-191298	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30177-30211	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	170-204	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023209	Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence	88-122	6	0.829
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87137-87171	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	138033-138067	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	43-77	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3372-3406	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208887-208921	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	42-76	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3371-3405	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219381-219415	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	42-76	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3371-3405	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210215-210249	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	42-76	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3371-3405	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191170-191204	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	27246-27280	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18350-18384	7	0.8
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15018-15052	7	0.8
NZ_CP044143_4	4.3\|3661697\|31\|NZ_CP044143\|CRT	3661697-3661727	31	NC_015512	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence	90200-90230	7	0.774
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	61916-61950	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4114-4148	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229148-229182	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229249-229283	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229350-229384	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229451-229485	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	203852-203886	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204038-204072	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204131-204165	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4113-4147	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239642-239676	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239743-239777	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239844-239878	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239945-239979	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214346-214380	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214532-214566	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214625-214659	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4113-4147	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230554-230588	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230655-230689	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230756-230790	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230857-230891	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205180-205214	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205366-205400	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205459-205493	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4113-4147	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211524-211558	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211625-211659	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211726-211760	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211827-211861	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186135-186169	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186321-186355	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186414-186448	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	14272-14306	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	6744-6778	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7392-7426	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	83590-83624	8	0.771
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84216-84250	8	0.771
NZ_CP044143_4	4.1\|3661575\|31\|NZ_CP044143\|PILER-CR,CRT	3661575-3661605	31	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	102901-102931	8	0.742
NZ_CP044143_4	4.1\|3661575\|31\|NZ_CP044143\|PILER-CR,CRT	3661575-3661605	31	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	313484-313514	8	0.742
NZ_CP044143_4	4.1\|3661575\|31\|NZ_CP044143\|PILER-CR,CRT	3661575-3661605	31	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	984473-984503	8	0.742
NZ_CP044143_4	4.6\|3661697\|32\|NZ_CP044143\|CRISPRCasFinder	3661697-3661728	32	NC_015512	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence	90200-90231	8	0.75
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	262-315	8	0.852
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12103-12156	8	0.852
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP019246	Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence	41406-41459	8	0.852
NZ_CP044143_6	6.1\|4696594\|44\|NZ_CP044143\|CRISPRCasFinder	4696594-4696637	44	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	210148-210191	8	0.818
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	386558-386592	9	0.743
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4013-4047	9	0.743
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4012-4046	9	0.743
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4012-4046	9	0.743
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4012-4046	9	0.743
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	13988-14022	9	0.743
NZ_CP044143_1	1.1\|1728706\|35\|NZ_CP044143\|CRISPRCasFinder	1728706-1728740	35	NZ_CP019246	Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence	41415-41449	9	0.743
NZ_CP044143_4	4.4\|3661575\|32\|NZ_CP044143\|CRISPRCasFinder	3661575-3661606	32	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	102900-102931	9	0.719
NZ_CP044143_4	4.4\|3661575\|32\|NZ_CP044143\|CRISPRCasFinder	3661575-3661606	32	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	313483-313514	9	0.719
NZ_CP044143_4	4.4\|3661575\|32\|NZ_CP044143\|CRISPRCasFinder	3661575-3661606	32	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	984472-984503	9	0.719
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229441-229494	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239935-239988	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7383-7436	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84207-84260	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87127-87180	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230847-230900	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211817-211870	10	0.815
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4105-4158	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3363-3416	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4104-4157	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3362-3415	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4104-4157	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3362-3415	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4104-4157	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3362-3415	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31242-31295	11	0.796
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	34-87	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4004-4057	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229239-229292	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229340-229393	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	33-86	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4003-4056	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239733-239786	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239834-239887	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	33-86	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4003-4056	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230645-230698	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230746-230799	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	33-86	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4003-4056	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211615-211668	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211716-211769	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15008-15061	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18340-18393	12	0.778
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30167-30220	13	0.759
NZ_CP044143_5	5.1\|4188188\|54\|NZ_CP044143\|CRISPRCasFinder	4188188-4188241	54	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	160-213	14	0.741

1. spacer 4.1|3661575|31|NZ_CP044143|PILER-CR,CRT matches to MK047640 (Phage NV18, complete genome) position: , mismatch: 1, identity: 0.968

tcaccaaaacagtgacaaaaactgtcaccaa	CRISPR spacer
tcaccaaaacagtgacaaaaagtgtcaccaa	Protospacer
********************* *********

2. spacer 4.4|3661575|32|NZ_CP044143|CRISPRCasFinder matches to MK047640 (Phage NV18, complete genome) position: , mismatch: 1, identity: 0.969

tcaccaaaacagtgacaaaaactgtcaccaaa	CRISPR spacer
tcaccaaaacagtgacaaaaagtgtcaccaaa	Protospacer
********************* **********

3. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 2, identity: 0.943

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ttcagcgcctgatgcgacgctggcgcgtcttatca	Protospacer
**********************.***********

4. spacer 4.1|3661575|31|NZ_CP044143|PILER-CR,CRT matches to MF417881 (Uncultured Caudovirales phage clone 7AX_3, partial genome) position: , mismatch: 2, identity: 0.935

tcaccaaaacagtgacaaaaactgtcaccaa	CRISPR spacer
tcaccaaatcagtgacaaaaagtgtcaccaa	Protospacer
******** ************ *********

5. spacer 4.4|3661575|32|NZ_CP044143|CRISPRCasFinder matches to MF417881 (Uncultured Caudovirales phage clone 7AX_3, partial genome) position: , mismatch: 2, identity: 0.938

tcaccaaaacagtgacaaaaactgtcaccaaa	CRISPR spacer
tcaccaaatcagtgacaaaaagtgtcaccaaa	Protospacer
******** ************ **********

6. spacer 7.1|4896503|38|NZ_CP044143|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

7. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 3, identity: 0.914

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tgtaacgcctgatgcgacgctgacgcgtcttatct	Protospacer
* .*.******************************

8. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 5, identity: 0.857

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accagcgcctgatgcgccgctgtcgcgtcttatca	Protospacer
 .************** ***** ***********

9. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 5, identity: 0.857

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ctcaacgcctgatgcgacgctggcgcgtcttagcg	Protospacer
.***.*****************.********* *

10. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gtttatgccagatgcgacgctgacgcgtcttatct	Protospacer
 *. ..*** *************************

11. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

12. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

13. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

14. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tcagatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*. ...****************************

15. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
*.....****************************

16. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
attgaagcctgatgcgacgctgacgcgtcttatca	Protospacer
 *... ****************************

17. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023209 (Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence) position: , mismatch: 6, identity: 0.829

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .*...****************************

18. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
cacgatgcctgatgcgacgctgccgcgtcttatca	Protospacer
. *...**************** ***********

19. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tgcgctgcctgatgcgacgctaatgcgtcttatca	Protospacer
* *. .***************.*.**********

20. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

21. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

22. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

23. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

24. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

25. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

26. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

27. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

28. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

29. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

30. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . .*.****************.***********

31. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgacgctgacgcgttttatca	Protospacer
 .*...**********************.*****

32. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accggtgccagatgcgacgcagacgcgtcttatca	Protospacer
 .*.*.*** ********** *************

33. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatca	Protospacer
 .....****************************

34. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ccaggtgcctgatgcgacgctggcgcgtcttatca	Protospacer
.. .*.****************.***********

35. spacer 4.3|3661697|31|NZ_CP044143|CRT matches to NC_015512 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence) position: , mismatch: 7, identity: 0.774

gcccaggg---atttgttcaatccagcgtgccgc	CRISPR spacer
---caaagtccatttgttcaacccatcgtgccgc	Protospacer
   **..*   **********.*** ********

36. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgccagatgcgacgctggcgcgtcttatct	Protospacer
 . ...*** ************.************

37. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

38. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

39. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

40. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

41. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

42. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

43. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

44. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

45. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

46. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

47. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

48. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

49. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

50. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

51. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

52. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

53. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

54. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

55. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

56. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

57. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

58. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

59. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

60. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

61. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatca	Protospacer
 . ...****************.***********

62. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

63. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

64. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

65. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatca	Protospacer
 . ...***************.************

66. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gccgatgcctgatgcgtcgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

67. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

68. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
accgatgcctgatgcgccgctgacgcgacttatca	Protospacer
 .*...********** ********** ******

69. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
tgaattacctgatgcgacgctggcgcatcttatca	Protospacer
*  * ..***************.***.*******

70. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatacgacgctgacgcgtcttatca	Protospacer
 . ...*******.********************

71. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ccggatgcctgatgcgacgctggcgcgtcttatca	Protospacer
.. ...****************.***********

72. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatacgacgctgacgcgtcttatca	Protospacer
 . ...*******.********************

73. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
ccggatgcctgatgcgacgctggcgcgtcttatca	Protospacer
.. ...****************.***********

74. spacer 4.1|3661575|31|NZ_CP044143|PILER-CR,CRT matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 8, identity: 0.742

tcaccaaaacagtgacaaaaactgtcaccaa	CRISPR spacer
tcaccaaaacagtgccaaagactcttgactg	Protospacer
************** ****.*** *.. * .

75. spacer 4.1|3661575|31|NZ_CP044143|PILER-CR,CRT matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 8, identity: 0.742

tcaccaaaacagtgacaaaaactgtcaccaa	CRISPR spacer
tcaccaaaacagtgccaaagactcttgactg	Protospacer
************** ****.*** *.. * .

76. spacer 4.1|3661575|31|NZ_CP044143|PILER-CR,CRT matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

tcaccaaaacagtgacaaaaactgtcaccaa	CRISPR spacer
tcaccaaaacggtgccaaaaactcttgactg	Protospacer
**********.*** ******** *.. * .

77. spacer 4.6|3661697|32|NZ_CP044143|CRISPRCasFinder matches to NC_015512 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence) position: , mismatch: 8, identity: 0.75

gcccaggg---atttgttcaatccagcgtgccgct	CRISPR spacer
---caaagtccatttgttcaacccatcgtgccgca	Protospacer
   **..*   **********.*** ********

78. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 8, identity: 0.852

cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catccggcaatcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaaa	Protospacer
**. * *** .* .***************** **********************

79. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 8, identity: 0.852

cacgccg-catcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-gctccgacgttcggtgcctgatgcgacgctggcgcgtcttatcaggcctacgag	Protospacer
 .* *** *.*.* **************************************.*.

80. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP019246 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence) position: , mismatch: 8, identity: 0.852

cacgccgcatcctg-tgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-aggcaccgtgctgatgtctgatgcgacgctggcgcgtcttatcagacctacaaa	Protospacer
 * **  *.* *** **.****************************.********

81. spacer 6.1|4696594|44|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 8, identity: 0.818

ttggcagtgtgcctgatgcgacgctgttcgcgtcttaccaggcc	CRISPR spacer
tgcacaagatgcctgatgcgacgctgtccgcgtcttatcaggcc	Protospacer
*  .**. .******************.*********.******

82. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgcctgatgcgatgctaacgcgtcttatca	Protospacer
 .....***********.***.************

83. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

84. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

85. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

86. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gcagatgcctgatgcgacgctagcgcgtcttatca	Protospacer
 . ...***************..***********

87. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
acggatgcccgatgcgacgctggcgcgtcttatcg	Protospacer
 . ...***.************.***********

88. spacer 1.1|1728706|35|NZ_CP044143|CRISPRCasFinder matches to NZ_CP019246 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttcagcgcctgatgcgacgctgacgcgtcttatct	CRISPR spacer
gctgatgtctgatgcgacgctggcgcgtcttatca	Protospacer
 .....*.**************.***********

89. spacer 4.4|3661575|32|NZ_CP044143|CRISPRCasFinder matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 9, identity: 0.719

tcaccaaaacagtgacaaaaactgtcaccaaa	CRISPR spacer
tcaccaaaacagtgccaaagactcttgactgt	Protospacer
************** ****.*** *.. * .

90. spacer 4.4|3661575|32|NZ_CP044143|CRISPRCasFinder matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 9, identity: 0.719

tcaccaaaacagtgacaaaaactgtcaccaaa	CRISPR spacer
tcaccaaaacagtgccaaagactcttgactgc	Protospacer
************** ****.*** *.. * .

91. spacer 4.4|3661575|32|NZ_CP044143|CRISPRCasFinder matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

tcaccaaaacagtgacaaaaactgtcaccaaa	CRISPR spacer
tcaccaaaacggtgccaaaaactcttgactgc	Protospacer
**********.*** ******** *.. * .

92. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 10, identity: 0.815

cacgccgcatcctg-tgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-cagtcgtgtgcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
   *.**..* * * ****************..**********************

93. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 10, identity: 0.815

cacgccgcatcctg-tgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-cagtcgtgtgcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
   *.**..* * * ****************..**********************

94. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 10, identity: 0.815

cacgcc-gcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-gcgctggtgccggatgcctgatgcgacgctggcgcgtcttatcatgcctacaaa	Protospacer
 .***. *...*  .****************************** *********

95. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 10, identity: 0.815

cacgcc-gcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-gcgctggtgccggatgcctgatgcgacgctggcgcgtcttatcatgcctacaaa	Protospacer
 .***. *...*  .****************************** *********

96. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 10, identity: 0.815

cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cattcggtgcacgatgcctgatgcgacgctgccgcgtcttatcaggcctacaaa	Protospacer
**. * *... * .***************** **********************

97. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 10, identity: 0.815

cacgccgcatcctg-tgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-cagtcgtgtgcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
   *.**..* * * ****************..**********************

98. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 10, identity: 0.815

cacgccgcatcctg-tgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
-cagtcgtgtgcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
   *.**..* * * ****************..**********************

99. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttatgcgcag------atgcctgatgcgacgctggcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************************** *********

100. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttgtacgcag------gtgcctgatgcgacgctggcgcgtcttatcatgcctacgag	Protospacer
      .**** *      ******************************* ******.*.

101. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttatgcgcag------atgcctgatgcgacgctggcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************************** *********

102. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttgtacgcag------gtgcctgatgcgacgctggcgcgtcttatcatgcctacgag	Protospacer
      .**** *      ******************************* ******.*.

103. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttatgcgcag------atgcctgatgcgacgctggcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************************** *********

104. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttgtacgcag------gtgcctgatgcgacgctggcgcgtcttatcatgcctacgag	Protospacer
      .**** *      ******************************* ******.*.

105. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttatgcgcag------atgcctgatgcgacgctggcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************************** *********

106. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.796

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagttgtacgcag------gtgcctgatgcgacgctggcgcgtcttatcatgcctacgag	Protospacer
      .**** *      ******************************* ******.*.

107. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 11, identity: 0.796

cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catccggtaatcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacagc	Protospacer
**. * *.* .* .***************** ********************.

108. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catttgtgcgctg------atgcctgatgcgacgctgacgcgtcttatcatgcctacaaa	Protospacer
      ..***.*      .*****************.************ *********

109. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
taattgtgcgcag------atgcctgatgcgacgctagcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************.************* *********

110. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

111. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

112. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catttgtgcgctg------atgcctgatgcgacgctgacgcgtcttatcatgcctacaaa	Protospacer
      ..***.*      .*****************.************ *********

113. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
taattgtgcgcag------atgcctgatgcgacgctagcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************.************* *********

114. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

115. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

116. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catttgtgcgctg------atgcctgatgcgacgctgacgcgtcttatcatgcctacaaa	Protospacer
      ..***.*      .*****************.************ *********

117. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
taattgtgcgcag------atgcctgatgcgacgctagcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************.************* *********

118. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

119. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

120. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catttgtgcgctg------atgcctgatgcgacgctgacgcgtcttatcatgcctacaaa	Protospacer
      ..***.*      .*****************.************ *********

121. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
taattgtgcgcag------atgcctgatgcgacgctagcgcgtcttatcatgcctacaaa	Protospacer
      ..*** *      .****************.************* *********

122. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

123. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
cagtcgtgcgcag------atgcctgatgcgacgctaacgcgtcttatcaggcctacaaa	Protospacer
      ..*** *      .****************..**********************

124. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 12, identity: 0.778

cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
caacaattaccaggtgcctgatgcgacgctggcgcgtcttatcatgcctacgag	Protospacer
**     .*.*  ******************************* ******.*.

125. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 12, identity: 0.778

------cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catttgtgcgctg------atgcctgatgcgacgctgacgcgtcttatcatgcctacaaa	Protospacer
      ..***.*      .*****************.************ *********

126. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 13, identity: 0.759

cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
catttgtgctctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaat	Protospacer
**. .    **. .*****************.************ ********

127. spacer 5.1|4188188|54|NZ_CP044143|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 14, identity: 0.741

cacgccgcatcctgtgcctgatgcgacgctggcgcgtcttatcaggcctacaaa	CRISPR spacer
tctccggcaattgaagcctgatgcgacgctgacgcgtcttatcaggcctacnag	Protospacer
. . * *** .. . ****************.******************* *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30662 : 86259

Escherichia_phage(23.08%)

protease,transposase,tail,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001299679.1\|30662_31919_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_001130692.1\|32132_32756_+	lipoprotein localization protein LolB	NA	NA	NA	NA
WP_001260332.1\|32755_33607_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_001298109.1\|33757_34705_+	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	3.9e-44	37.8
WP_001033352.1\|34829_36509_+	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	1.3e-23	23.6
WP_000823885.1\|36563_36842_-	stress-induced protein YchH	NA	NA	NA	NA
WP_000152933.1\|37119_37704_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000505866.1\|37820_38912_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_000733713.1\|41733_42804_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_001302889.1\|42814_43447_+	dihydroxyacetone kinase ADP-binding subunit DhaL	NA	NA	NA	NA
WP_001302890.1\|43457_44876_+	dihydroxyacetone kinase subunit DhaM	NA	NA	NA	NA
WP_001366914.1\|45188_45317_+	hypothetical protein	NA	NA	NA	NA
WP_001304187.1\|45422_46880_+	alpha,alpha-trehalase TreA	NA	NA	NA	NA
WP_001459046.1\|46907_47108_+	hypothetical protein	NA	NA	NA	NA
WP_000060146.1\|47215_48238_+	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001223662.1\|48237_49218_+	iron ABC transporter permease	NA	NA	NA	NA
WP_000173324.1\|49214_49973_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.5e-14	29.7
WP_000903990.1\|49982_50627_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_010917800.1\|50571_50853_+	hypothetical protein	NA	NA	NA	NA
WP_000576838.1\|50791_51646_+	ModD protein	NA	NA	NA	NA
WP_001302893.1\|51671_53642_+	TonB-dependent receptor	NA	NA	NA	NA
WP_000511315.1\|53691_53946_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_000020148.1\|54146_54743_+	flagellar brake protein	NA	NA	NA	NA
WP_085952403.1\|54794_56007_+\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	3.4e-170	99.7
WP_001295616.1\|56195_56807_-	membrane-bound lytic murein transglycosylase EmtA	NA	NA	NA	NA
WP_000051572.1\|56906_57821_+	muramoyltetrapeptide carboxypeptidase	NA	NA	NA	NA
WP_000340206.1\|57916_59653_+	potassium/proton antiporter	NA	NA	NA	NA
WP_000197859.1\|60044_61115_-	catabolic alanine racemase DadX	NA	NA	NA	NA
WP_001266908.1\|61124_62423_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_000190855.1\|62785_64318_+	SpoVR family protein	NA	NA	NA	NA
WP_000234823.1\|64369_65089_-	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_000406391.1\|65310_66852_+	Na(+)/H(+) antiporter NhaB	NA	NA	NA	NA
WP_000943459.1\|66997_67528_+	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_000457644.1\|67573_68842_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	3.0e-209	83.2
WP_000897378.1\|68841_69261_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	6.9e-38	62.1
WP_001304191.1\|69633_70545_+	hemolysin HlyE	NA	NA	NA	NA
WP_000807626.1\|70751_71213_-	YcgN family cysteine cluster protein	NA	NA	NA	NA
WP_000284277.1\|71289_71949_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_001295992.1\|72020_72314_-	hypothetical protein	NA	NA	NA	NA
WP_000695220.1\|72554_72956_+	hypothetical protein	NA	NA	NA	NA
WP_001056834.1\|73058_73427_-	hypothetical protein	NA	NA	NA	NA
WP_000072536.1\|73946_74642_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_000101055.1\|74665_75478_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_001185665.1\|75481_75748_+	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_000279979.1\|76913_77534_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	4.0e-114	100.0
WP_151121002.1\|77443_77635_-	hypothetical protein	A0A0N7BTS3	Escherichia_phage	2.9e-07	100.0
WP_085949317.1\|77600_78814_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	9.3e-168	99.3
WP_000361110.1\|79613_80198_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_071781823.1\|80375_80561_-	hypothetical protein	NA	NA	NA	NA
WP_001201843.1\|80695_81649_+\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001226373.1\|81835_83320_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000998048.1\|83622_85161_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|85210_85558_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|85554_85935_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000937476.1\|86010_86259_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.7e-12	76.5

DBSCAN-SWA_2

89814 : 204175

147

Enterobacteria_phage(32.73%)

portal,head,tRNA,terminase,lysis,tail,holin,capsid,integrase,protease

attL 189742:189762|attR 210832:210852

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000885629.1\|89814_90396_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.3e-100	93.2
WP_000268883.1\|90395_93311_-	membrane protein	A0A0P0ZE15	Stx2-converting_phage	1.5e-57	98.3
WP_001230340.1\|93375_93975_-	Ail/Lom family outer membrane beta-barrel protein	A0A291AWV3	Escherichia_phage	8.8e-111	99.0
WP_000515612.1\|94041_97440_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	90.7
WP_000090920.1\|97500_98133_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	1.7e-96	99.5
WP_001152612.1\|98817_99516_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.1e-132	98.7
WP_000847331.1\|99515_99845_-\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	2.5e-59	100.0
WP_000840323.1\|99841_102391_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	87.3
WP_000459457.1\|102383_102818_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479161.1\|102799_103222_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-70	96.4
WP_001143002.1\|103237_103978_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	8.3e-127	95.9
WP_000683105.1\|103985_104381_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_000975100.1\|104377_104956_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_000752995.1\|104967_105321_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.9e-62	99.1
WP_000158906.1\|105332_105731_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000063265.1\|105772_106798_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	8.7e-191	98.8
WP_001295978.1\|106853_107186_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
WP_000123254.1\|107195_108515_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.4e-232	98.2
WP_001301524.1\|108495_110097_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-307	98.7
WP_000198153.1\|110093_110300_-\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001027374.1\|110296_112222_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
WP_000453564.1\|112196_112742_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.6e-93	97.8
WP_001300120.1\|113130_113325_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	1.5e-27	98.4
WP_001031427.1\|113489_113696_-	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	5.8e-30	100.0
WP_000079504.1\|113981_114392_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	2.7e-71	98.5
WP_000738495.1\|114683_114977_+	serum resistance lipoprotein Bor	K7PL54	Enterobacteria_phage	1.5e-47	99.0
WP_010917798.1\|115067_115250_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	4.7e-15	93.3
WP_001180487.1\|115466_115943_-	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	4.3e-84	95.6
WP_000544528.1\|115929_116235_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	7.0e-40	87.6
WP_001097228.1\|116556_117246_-	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.7e-57	48.9
WP_000971093.1\|117242_117383_-	YlcG family protein	K7PHH3	Enterobacteria_phage	7.7e-10	71.1
WP_001099695.1\|117379_117742_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	7.3e-60	95.7
WP_000774504.1\|117738_118029_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_000224907.1\|118021_118192_-	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_001053040.1\|118191_118647_-	hypothetical protein	I6PD71	Cronobacter_phage	8.6e-58	64.9
WP_071525067.1\|118837_119029_-	hypothetical protein	NA	NA	NA	NA
WP_000709077.1\|119148_120675_-	recombinase family protein	Q3HQV4	Burkholderia_phage	1.2e-31	31.1
WP_001302833.1\|120732_120855_-	hypothetical protein	NA	NA	NA	NA
WP_001070446.1\|120919_121252_-	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_000145915.1\|121319_121622_-	protein ren	A0A0N6WES4	Escherichia_phage	1.1e-42	95.7
WP_000788869.1\|121618_122320_-	Replication protein P	A0A0P0ZD31	Stx2-converting_phage	1.3e-129	99.6
WP_000945520.1\|122316_123141_-	replication protein	A0A0K2FJ31	Enterobacteria_phage	3.8e-96	69.3
WP_000088655.1\|123244_123481_+	excisionase	NA	NA	NA	NA
WP_000741454.1\|123470_124613_+\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	8.1e-206	100.0
WP_000444477.1\|124726_125977_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_001248690.1\|126148_126802_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000476093.1\|126811_127273_+	phosphatase NudJ	NA	NA	NA	NA
WP_001301861.1\|127326_128433_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_001301618.1\|128468_129110_+	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000423729.1\|129113_130484_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001265474.1\|130652_131324_+	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000735407.1\|131323_132784_+	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001302829.1\|133087_133336_+	hypothetical protein	NA	NA	NA	NA
WP_000133425.1\|133640_133922_-	hypothetical protein	NA	NA	NA	NA
WP_000127893.1\|133935_135597_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	1.5e-277	81.6
WP_000113645.1\|135580_135937_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	9.4e-52	81.4
WP_000174068.1\|136060_136243_-	hypothetical protein	NA	NA	NA	NA
WP_001145903.1\|136226_136667_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	1.2e-61	71.9
WP_000134113.1\|136666_136963_-	hypothetical protein	A0A2H4JD08	uncultured_Caudovirales_phage	4.0e-32	65.3
WP_001020660.1\|136959_137298_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	1.9e-30	52.7
WP_000171117.1\|137294_138470_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	2.4e-184	79.9
WP_000504050.1\|138506_139079_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-61	63.5
WP_001137345.1\|139118_140276_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	2.8e-137	64.9
WP_001132080.1\|140567_140792_-	hypothetical protein	NA	NA	NA	NA
WP_000233299.1\|140916_141189_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_000126692.1\|141199_141610_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_000198852.1\|141606_141858_-	hypothetical protein	NA	NA	NA	NA
WP_000761781.1\|142228_144361_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	5.8e-173	52.6
WP_000770148.1\|144357_144657_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_000794515.1\|144662_144905_-	hypothetical protein	NA	NA	NA	NA
WP_000659212.1\|144894_145086_-	hypothetical protein	A0A1W6JPD9	Morganella_phage	1.7e-07	50.0
WP_000920682.1\|145085_145271_-	hypothetical protein	NA	NA	NA	NA
WP_001453500.1\|145263_145461_-	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_001304194.1\|145486_146230_-	hypothetical protein	NA	NA	NA	NA
WP_000953272.1\|146287_146476_-	AlpA family transcriptional regulator	A0A2H4JB58	uncultured_Caudovirales_phage	2.0e-13	66.0
WP_000085257.1\|146840_148070_-\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	6.4e-132	55.9
WP_001301987.1\|148318_149440_+	cupin domain-containing protein	NA	NA	NA	NA
WP_000359446.1\|149488_150715_-	peptidase T	NA	NA	NA	NA
WP_000531594.1\|150964_152101_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
WP_000799385.1\|152084_152948_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_001303923.1\|152978_153191_+	hypothetical protein	NA	NA	NA	NA
WP_000938118.1\|153311_154673_+	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	1.4e-50	29.2
WP_001303921.1\|154733_155009_+	hypothetical protein	NA	NA	NA	NA
WP_001301834.1\|155088_155214_-	hypothetical protein	Q8HAB2	Salmonella_phage	8.7e-05	58.3
WP_001301984.1\|157317_160719_-	type III secretion system effector EspN	A0A0N7KZG3	Stx2-converting_phage	1.7e-219	39.2
WP_115801847.1\|163676_163766_-	hypothetical protein	NA	NA	NA	NA
WP_071526731.1\|163778_164015_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	2.8e-20	80.3
WP_000967271.1\|163960_164698_-\|tail	phage tail protein	B6ETG2	Enterobacteria_phage	8.2e-151	100.0
WP_000835336.1\|164751_165630_-	phage repressor protein/antirepressor Ant	I6R977	Salmonella_phage	2.5e-93	77.2
WP_010904626.1\|165932_166043_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_000170104.1\|166152_166407_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_001179478.1\|166423_167122_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	3.1e-131	97.8
WP_000807950.1\|167121_167463_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	3.3e-62	99.1
WP_000212899.1\|167455_170698_-\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	97.9
WP_001453698.1\|170750_170960_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|171055_171430_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001275506.1\|171435_172152_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	5.0e-129	99.6
WP_000133388.1\|172210_172555_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|172551_172998_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007905.1\|172994_173345_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125988.1\|173354_173681_-\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001304108.1\|173683_176263_-\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	97.3
WP_001063094.1\|176208_176430_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	1.3e-35	98.6
WP_000173030.1\|176474_178412_-\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	100.0
WP_001507810.1\|178475_180137_-\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.5
WP_000958416.1\|180133_180697_-\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	4.7e-90	100.0
WP_000279786.1\|180986_181352_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_001302295.1\|181393_181579_+	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	1.4e-19	88.5
WP_000347013.1\|181708_181849_-	hypothetical protein	NA	NA	NA	NA
WP_000735655.1\|182205_182430_-	hypothetical protein	NA	NA	NA	NA
WP_001208682.1\|182494_182701_-	hypothetical protein	H6WRZ6	Salmonella_phage	7.1e-12	64.7
WP_000539792.1\|182928_183075_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|183074_183644_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992148.1\|183914_184448_-	lysozyme	B6DZ92	Enterobacteria_phage	3.0e-102	99.4
WP_000731241.1\|184498_184843_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.7e-58	99.1
WP_000284518.1\|184847_185063_-\|holin	holin	Q6H9V8	Enterobacteria_phage	2.0e-33	100.0
WP_001289717.1\|185138_185408_-	DUF826 domain-containing protein	A0A2R2Z348	Escherichia_phage	8.2e-08	75.3
WP_001213059.1\|185445_185628_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	1.0e-14	67.8
WP_000023170.1\|185775_187713_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	2.5e-292	76.8
WP_000216629.1\|188027_188195_-	DUF3927 domain-containing protein	H6WZJ7	Escherichia_phage	1.9e-10	72.5
WP_000762929.1\|188791_189613_-	antitermination protein	K7P7B9	Enterobacteria_phage	1.3e-83	58.6
WP_001217410.1\|189609_189984_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.1e-33	62.7
189742:189762	attL	NA	NA	NA	NA
WP_001265168.1\|189996_191046_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-107	53.4
WP_001341388.1\|191047_191326_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_000887477.1\|191493_191706_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.1e-18	68.6
WP_001278450.1\|191894_191999_-	hypothetical protein	NA	NA	NA	NA
WP_000207955.1\|192114_192702_-	DUF551 domain-containing protein	K7PH57	Enterobacteria_phage	7.5e-38	45.8
WP_001014296.1\|192704_192896_-	hypothetical protein	G9L660	Escherichia_phage	1.6e-26	98.4
WP_000515959.1\|192897_193335_-	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	1.9e-38	94.0
WP_000156547.1\|193321_193639_-	hypothetical protein	A0A088CQ13	Enterobacteria_phage	4.4e-45	90.0
WP_001017965.1\|193592_193910_-	DUF4752 family protein	A0A1I9LJV1	Stx_converting_phage	2.1e-42	92.4
WP_001310212.1\|193899_194202_-	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	1.9e-45	87.9
WP_000017339.1\|194198_194516_-	hypothetical protein	A0A222YXX1	Escherichia_phage	1.1e-32	70.6
WP_000451012.1\|194512_195229_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.1e-71	62.4
WP_001301518.1\|195262_195685_-	hypothetical protein	A0A0U2JGJ0	Escherichia_phage	1.8e-73	91.4
WP_001262323.1\|195716_196754_-	hypothetical protein	A0A0U2RT81	Escherichia_phage	3.3e-89	79.5
WP_000693915.1\|196822_197248_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000711018.1\|197231_197555_-	transcriptional regulator	A0A0R6PH31	Moraxella_phage	6.2e-10	44.9
WP_000948454.1\|197679_198156_+	hypothetical protein	A0A2D1GNH0	Pseudomonas_phage	5.7e-12	53.4
WP_001414141.1\|198471_198624_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	1.0e-07	55.3
WP_000559928.1\|198738_199254_-	hypothetical protein	NA	NA	NA	NA
WP_077699040.1\|199386_199776_+	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	1.3e-38	60.0
WP_000003742.1\|199837_200107_+	excisionase	NA	NA	NA	NA
WP_000074985.1\|200075_201194_+\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	1.0e-83	43.9
WP_000580316.1\|201360_202155_+	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_000759316.1\|202151_203198_+	spermidine/putrescine ABC transporter substrate-binding protein PotD	NA	NA	NA	NA
WP_000952736.1\|203353_204175_-	NAD-dependent protein deacylase	A0A2I7S9Y2	Vibrio_phage	5.6e-23	35.6
210832:210852	attR	NA	NA	NA	NA

DBSCAN-SWA_3

432965 : 439626

Stx_converting_phage(36.36%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001028088.1\|432965_433460_+	pyrimidine utilization flavin reductase protein F	Q9KX93	Enterobacteria_phage	7.6e-52	99.0
WP_001301708.1\|433480_434809_+	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	1.8e-236	100.0
WP_001273654.1\|434891_434999_-	hypothetical protein	Q9KX95	Enterobacteria_phage	3.4e-10	100.0
WP_024177246.1\|435364_435571_-	hypothetical protein	Q7Y2P9	Escherichia_phage	1.3e-26	100.0
WP_000203859.1\|435988_436618_+	phage antirepressor Ant	A0A1I9LJV2	Stx_converting_phage	1.5e-113	100.0
WP_000763353.1\|436665_436887_+	TraR/DksA family transcriptional regulator	A0A0N7C094	Escherichia_phage	1.3e-35	100.0
WP_001024844.1\|436883_437168_+	DUF4752 family protein	A0A1I9LJV1	Stx_converting_phage	3.2e-47	100.0
WP_000426668.1\|438052_438448_+	hypothetical protein	A0A1I9LJU8	Stx_converting_phage	4.7e-68	100.0
WP_000935259.1\|438681_438894_+	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000756595.1\|439013_439358_+	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	4.6e-56	100.0
WP_000971668.1\|439437_439626_-	hypothetical protein	A0A0P0ZAD9	Stx2-converting_phage	4.1e-30	100.0

DBSCAN-SWA_4

448355 : 583270

175

Escherichia_phage(35.71%)

portal,bacteriocin,head,terminase,transposase,tail,holin,capsid,integrase,protease

attL 529818:529833|attR 585034:585049

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000012450.1\|448355_449621_-	hypothetical protein	A0A1I9LJU3	Stx_converting_phage	1.4e-206	100.0
WP_000540391.1\|449631_449883_-\|bacteriocin	bacteriocin	A0A2R2Z351	Escherichia_phage	7.9e-13	100.0
WP_000455644.1\|449892_450339_-	hypothetical protein	A0A1I9LJU1	Stx_converting_phage	1.4e-76	100.0
WP_000509481.1\|450341_450998_-	hypothetical protein	A0A2R2Z361	Escherichia_phage	2.4e-109	100.0
WP_000035558.1\|451091_451493_-	hypothetical protein	A0A2R2Z359	Escherichia_phage	3.7e-73	100.0
WP_000078907.1\|451549_451690_-	Hok/Gef family protein	A0A2R2X2B4	Escherichia_phage	3.1e-19	100.0
WP_000835360.1\|451922_452657_-	outer membrane protein	A0A2R2Z365	Escherichia_phage	1.3e-135	100.0
WP_001301884.1\|452747_453365_-	hypothetical protein	A0A2R2Z362	Escherichia_phage	1.1e-121	100.0
WP_000455634.1\|453370_453649_-	outer membrane protein	A0A2R2Z367	Escherichia_phage	1.1e-50	100.0
WP_000197192.1\|453663_454932_-	host specificity protein J	A0A2R2Z364	Escherichia_phage	4.9e-220	100.0
WP_001146326.1\|454928_456554_-	hypothetical protein	A0A1I9LJT3	Stx_converting_phage	0.0e+00	100.0
WP_001303606.1\|456848_457037_-	hypothetical protein	A0A2R2Z344	Escherichia_phage	6.9e-30	100.0
WP_001024006.1\|457176_457446_-\|tail	phage tail protein	A0A1I9LJT0	Stx_converting_phage	2.2e-45	100.0
WP_000117994.1\|457447_459385_-\|tail	tail fiber protein	A0A1I9LJS9	Stx_converting_phage	1.1e-64	100.0
WP_000207924.1\|459381_460032_-	hypothetical protein	A0A1I9LJS8	Stx_converting_phage	2.7e-121	100.0
WP_000829200.1\|460031_460595_-	hypothetical protein	A0A2R2Z349	Escherichia_phage	3.2e-102	100.0
WP_001290743.1\|460578_461040_-	hypothetical protein	A0A2R2Z354	Escherichia_phage	7.8e-75	100.0
WP_001140442.1\|461089_461479_-	hypothetical protein	A0A2R2Z353	Escherichia_phage	9.9e-63	100.0
WP_000214474.1\|461534_462749_-\|capsid	N4-gp56 family major capsid protein	A0A2R2Z358	Escherichia_phage	1.3e-233	100.0
WP_000345010.1\|462772_463780_-	hypothetical protein	A0A2R2Z355	Escherichia_phage	2.3e-180	100.0
WP_000787519.1\|463937_466082_-\|portal	portal protein	A0A2R2Z346	Escherichia_phage	0.0e+00	100.0
WP_000143988.1\|466081_467788_-\|terminase	terminase	A0A2R2Z350	Escherichia_phage	0.0e+00	100.0
WP_001086069.1\|467768_468575_-\|terminase	terminase	A0A2R2Z334	Escherichia_phage	7.6e-134	100.0
WP_001301714.1\|468630_468834_-	hypothetical protein	A0A2R2Z338	Escherichia_phage	7.7e-35	100.0
WP_000738505.1\|468983_469277_+	serum resistance lipoprotein Bor	A0A2R2X2B2	Escherichia_phage	6.8e-48	100.0
WP_015971382.1\|469367_469553_-	Rz1 protein precursor	A0A0P0ZBL2	Stx2-converting_phage	1.2e-18	100.0
WP_000539792.1\|469780_469927_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|469926_470496_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000087728.1\|470766_471300_-	lysozyme	A0A1I9LJR4	Stx_converting_phage	1.8e-102	100.0
WP_000284506.1\|471304_471520_-\|holin	holin	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_001290212.1\|471596_471869_-	DUF826 domain-containing protein	A0A1I9LJR2	Stx_converting_phage	1.2e-22	100.0
WP_000143458.1\|471909_472089_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_000874499.1\|472223_474161_-	SASA family carbohydrate esterase	A0A1I9LJQ8	Stx_converting_phage	0.0e+00	100.0
WP_000738068.1\|474647_474917_-	Shiga toxin Stx2a subunit B	A0A2R2Z326	Escherichia_phage	1.2e-43	100.0
WP_000649753.1\|474928_475888_-	Shiga toxin Stx2c subunit A	Q776Q3	Enterobacteria_phage	5.6e-176	100.0
WP_001304085.1\|476270_476423_-	hypothetical protein	A0A0N7C2V5	Escherichia_phage	5.2e-20	100.0
WP_015967940.1\|476437_476683_+	hypothetical protein	Q7Y2J1	Escherichia_phage	2.7e-34	100.0
WP_001507023.1\|476671_477106_-	phage antitermination Q family protein	A0A0P0ZCW9	Stx2-converting_phage	2.8e-82	100.0
WP_000144764.1\|477098_477293_-	protein ninH	G9L694	Escherichia_phage	1.9e-30	100.0
WP_001107955.1\|477289_477895_-	recombination protein NinG	A0A1I9LJQ2	Stx_converting_phage	2.3e-98	100.0
WP_001004020.1\|477894_478617_-	DNA-binding protein	A0A1I9LJQ1	Stx_converting_phage	7.8e-130	100.0
WP_000335902.1\|478768_479818_-	hypothetical protein	Q9T208	Enterobacteria_phage	1.3e-181	100.0
WP_000153280.1\|479999_480527_-	phage N-6-adenine-methyltransferase	A0A1I9LJP9	Stx_converting_phage	9.5e-101	100.0
WP_000814576.1\|480523_480970_-	recombination protein NinB	A0A0N7C2V1	Escherichia_phage	2.4e-81	100.0
WP_001281772.1\|480926_481163_-	restriction alleviation protein, Lar family	Q8HA09	Enterobacteria_phage	1.2e-39	100.0
WP_000103679.1\|481173_481389_-	hypothetical protein	A0A1I9LJP7	Stx_converting_phage	1.3e-32	100.0
WP_001000127.1\|481521_481800_-	hypothetical protein	Q9ZWY1	Enterobacteria_phage	3.4e-49	100.0
WP_000145931.1\|481870_482161_-	protein ren	A0A1I9LJP5	Stx_converting_phage	9.6e-47	100.0
WP_000788928.1\|482157_482859_-	Replication protein P	C1JJ58	Enterobacteria_phage	3.4e-130	100.0
WP_000185454.1\|482855_483794_-	replication protein	A0A1I9LJP3	Stx_converting_phage	1.3e-172	100.0
WP_000438541.1\|483826_484123_-	hypothetical protein	C1JJ56	Enterobacteria_phage	8.9e-48	100.0
WP_001180318.1\|484261_484489_-	transcriptional regulator	G9L677	Escherichia_phage	7.8e-36	100.0
WP_000250473.1\|484567_485275_+	helix-turn-helix transcriptional regulator	G9L676	Escherichia_phage	1.5e-133	100.0
WP_000885203.1\|485335_485677_+	DUF3024 domain-containing protein	A0A1I9LJN9	Stx_converting_phage	3.9e-63	100.0
WP_001221211.1\|485744_486206_+	hypothetical protein	G9L674	Escherichia_phage	1.3e-77	100.0
WP_000957426.1\|486199_487246_+	serine/threonine protein kinase	G9L673	Escherichia_phage	5.2e-207	100.0
WP_000198444.1\|487901_488285_+	hypothetical protein	G9L671	Escherichia_phage	3.9e-64	100.0
WP_000167595.1\|488343_488814_+	hypothetical protein	A0A1I9LJN4	Stx_converting_phage	3.7e-88	100.0
WP_000065377.1\|488964_489333_+	DUF2528 family protein	A0A1I9LJN3	Stx_converting_phage	7.6e-65	100.0
WP_001198863.1\|489405_489570_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	A0A0N7KZ85	Stx2-converting_phage	6.2e-27	100.0
WP_000372941.1\|489538_489682_+	host cell division inhibitory peptide Kil	A0A1I9LJN2	Stx_converting_phage	1.2e-18	100.0
WP_015983550.1\|489636_489789_+	hypothetical protein	Q08J51	Stx2-converting_phage	1.2e-21	100.0
WP_000995439.1\|489757_490054_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000100847.1\|490059_490845_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000186740.1\|490841_491519_+	YqaJ viral recombinase family protein	A0A1I9LJM9	Stx_converting_phage	4.6e-132	100.0
WP_001303590.1\|491518_491701_+	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	7.4e-29	100.0
WP_000548547.1\|491673_491865_+	DUF1382 family protein	A0A1I9LJM8	Stx_converting_phage	1.9e-27	100.0
WP_001444000.1\|491875_492157_+	cell division protein ZapA	A0A0P0ZBQ0	Stx2-converting_phage	1.9e-47	100.0
WP_000763383.1\|492255_492477_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.9e-35	100.0
WP_021497462.1\|492473_493247_+	ead/Ea22-like family protein	A0A1I9LJM5	Stx_converting_phage	2.3e-143	100.0
WP_000797281.1\|493398_493587_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	2.8e-31	100.0
WP_000951705.1\|493588_493804_+	hypothetical protein	A0A1I9LJM3	Stx_converting_phage	3.0e-37	100.0
WP_001142590.1\|493805_494024_+	DUF4014 domain-containing protein	A0A1I9LJM2	Stx_converting_phage	3.5e-33	100.0
WP_000212746.1\|494025_494313_+	hypothetical protein	A0A1I9LJM1	Stx_converting_phage	9.2e-50	100.0
WP_001303965.1\|495288_495588_+	hypothetical protein	G9L655	Escherichia_phage	2.4e-53	100.0
WP_001208773.1\|495673_495958_+	excisionase family protein	G9L654	Escherichia_phage	9.1e-50	100.0
WP_000013654.1\|496010_497321_+\|integrase	site-specific integrase	A0A1I9LJL6	Stx_converting_phage	3.2e-254	100.0
WP_000607020.1\|497317_497896_+	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_001143120.1\|497916_498144_+	hypothetical protein	NA	NA	NA	NA
WP_001044286.1\|498181_499423_-	bifunctional glucose-1-phosphatase/inositol phosphatase	NA	NA	NA	NA
WP_000420639.1\|501230_502151_+	curved DNA-binding protein	A0A1V0SIM1	Klosneuvirus	2.5e-11	43.0
WP_000024560.1\|502150_502456_+	chaperone modulator CbpM	NA	NA	NA	NA
WP_000209883.1\|502609_503209_-	molecular chaperone TorD	NA	NA	NA	NA
WP_001063176.1\|503205_505752_-	trimethylamine-N-oxide reductase TorA	A0A077SK27	Escherichia_phage	1.7e-70	30.7
WP_001230236.1\|505751_506924_-	pentaheme c-type cytochrome TorC	NA	NA	NA	NA
WP_001120119.1\|507053_507746_+	two-component system response regulator TorR	W8CYM9	Bacillus_phage	4.5e-18	28.0
WP_001264927.1\|507718_508747_-	TMAO reductase system periplasmic protein TorT	NA	NA	NA	NA
WP_000818441.1\|511645_512719_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_050554528.1\|512767_512902_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001303885.1\|512929_513160_-	protein YmcE	NA	NA	NA	NA
WP_071524879.1\|513134_513323_-	cold-shock protein	NA	NA	NA	NA
WP_000066490.1\|513333_513546_-	cold shock protein CspG	A0A1W6JNX5	Morganella_phage	7.8e-22	71.4
WP_000087763.1\|513831_514044_+	cold shock-like protein CspH	NA	NA	NA	NA
WP_001299283.1\|514485_514791_+	threonine-rich inner membrane protein GfcA	NA	NA	NA	NA
WP_001301846.1\|514897_515542_+	YjbF family lipoprotein	NA	NA	NA	NA
WP_001038071.1\|515538_516285_+	hypothetical protein	NA	NA	NA	NA
WP_000742329.1\|516284_518381_+	YjbH domain-containing protein	NA	NA	NA	NA
WP_001295357.1\|518426_519566_+	polysaccharide export protein	NA	NA	NA	NA
WP_000057871.1\|519553_520000_+	protein-tyrosine-phosphatase Etp	NA	NA	NA	NA
WP_000208668.1\|520019_522200_+	tyrosine-protein kinase	NA	NA	NA	NA
WP_001301957.1\|522319_523624_-	AppA family phytase/histidine-type acid phosphatase	NA	NA	NA	NA
WP_000270305.1\|523703_523796_-	cytochrome bd-II oxidase subunit CbdX	NA	NA	NA	NA
WP_000460778.1\|523808_524945_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_000263572.1\|524956_526501_-	cytochrome bd-II oxidase subunit 1	NA	NA	NA	NA
WP_000004940.1\|526634_527492_-	hydrogenase expression/formation protein	NA	NA	NA	NA
WP_000063969.1\|527488_527887_-	hydrogenase-1 operon protein HyaE	NA	NA	NA	NA
WP_000003653.1\|527883_528471_-\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_001186424.1\|528467_529175_-	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000107391.1\|529193_530987_-	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
529818:529833	attL	NA	NA	NA	NA
WP_001301613.1\|530983_532102_-	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_001303884.1\|532719_532902_+	hypothetical protein	H6WZN3	Escherichia_phage	1.1e-21	89.7
WP_001023352.1\|534375_534645_-\|tail	phage tail protein	A0A0P0ZEF0	Stx2-converting_phage	3.4e-46	100.0
WP_001230444.1\|536024_536624_-	outer membrane protein	A0A0P0ZCF6	Stx2-converting_phage	8.8e-111	99.0
WP_000515108.1\|536691_540165_-	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	96.5
WP_000649830.1\|540298_540826_+	superoxide dismutase family protein	Q9MC02	Salmonella_phage	2.0e-58	59.9
WP_001303882.1\|540856_541063_-	hypothetical protein	NA	NA	NA	NA
WP_050546863.1\|541016_541649_-\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	5.8e-105	99.5
WP_000194760.1\|541594_542338_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	2.4e-150	99.6
WP_001151078.1\|542348_543047_-\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	2.9e-129	98.3
WP_000847304.1\|543046_543376_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	2.2e-55	95.4
WP_000082450.1\|543372_545952_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	81.7
WP_000533402.1\|545932_546346_-\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000479117.1\|546372_546804_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	68.1
WP_029208397.1\|546817_547558_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.6e-130	98.0
WP_001301534.1\|547539_547806_-	hypothetical protein	NA	NA	NA	NA
WP_000256723.1\|547863_548211_-\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.6e-22	58.1
WP_001254002.1\|548247_549753_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-100	54.2
WP_000831796.1\|549742_551335_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.7e-182	60.5
WP_000259002.1\|551331_551538_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_001302857.1\|551521_553450_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	3.3e-260	65.9
WP_001301919.1\|553421_553664_-	DNA packaging protein	NA	NA	NA	NA
WP_000998048.1\|553713_555252_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|555301_555649_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|555645_556026_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000235421.1\|556101_556377_-	hypothetical protein	A0A1I9KFT4	Aeromonas_phage	2.4e-10	51.5
WP_000411791.1\|557127_557334_+\|holin	holin	Q6H9V8	Enterobacteria_phage	4.5e-30	97.1
WP_001303880.1\|557296_557641_-	hypothetical protein	NA	NA	NA	NA
WP_000138558.1\|557589_557862_-	hypothetical protein	NA	NA	NA	NA
WP_001303879.1\|557794_557989_+	hypothetical protein	NA	NA	NA	NA
WP_001003118.1\|558021_558555_+	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.1e-99	94.4
WP_000675931.1\|558775_558889_+	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_012816791.1\|559110_559296_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_001303878.1\|559823_560138_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_000874392.1\|561494_563345_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.1
WP_042853491.1\|563462_563666_+	hypothetical protein	Q8VNP0	Enterobacteria_phage	1.8e-28	96.7
WP_000261909.1\|564111_564825_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001303877.1\|564919_565159_-	hypothetical protein	Q9MC00	Enterobacteria_phage	7.7e-18	98.0
WP_000265265.1\|565445_566264_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000090264.1\|566415_566787_-	antitermination protein	Q777W5	Enterobacteria_phage	4.0e-53	83.2
WP_001217436.1\|566776_567148_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_001265172.1\|567160_568210_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.9
WP_001341388.1\|568211_568490_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001013642.1\|568657_568870_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.5e-25	95.4
WP_000955173.1\|568914_569052_+	hypothetical protein	Q7Y2Q9	Escherichia_phage	5.4e-08	96.6
WP_001151233.1\|570541_570955_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	9.8e-61	89.1
WP_000450992.1\|570970_571741_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	6.1e-80	64.5
WP_000788751.1\|571762_572509_-	replication protein	A0A088CBP4	Shigella_phage	6.2e-114	84.2
WP_001205823.1\|572515_573607_-	hypothetical protein	V5URT9	Shigella_phage	5.1e-133	70.0
WP_000273724.1\|573685_574141_+	hypothetical protein	NA	NA	NA	NA
WP_000693855.1\|574347_574773_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000887453.1\|574756_575029_-	hypothetical protein	A0A0U2S629	Escherichia_phage	1.1e-12	45.8
WP_000986592.1\|575137_575539_+	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	7.4e-13	54.5
WP_000536233.1\|575566_575758_+	hypothetical protein	NA	NA	NA	NA
WP_001303876.1\|575757_576045_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_071525099.1\|576046_576265_+	hypothetical protein	NA	NA	NA	NA
WP_000379575.1\|576322_576478_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_000394511.1\|576619_577009_+	hypothetical protein	NA	NA	NA	NA
WP_001133046.1\|577195_577381_-	hypothetical protein	NA	NA	NA	NA
WP_001303875.1\|577382_577688_-	hypothetical protein	NA	NA	NA	NA
WP_000413705.1\|577954_578143_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001098307.1\|578139_578331_+	DUF1482 family protein	NA	NA	NA	NA
WP_000034474.1\|578424_580896_+	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_000273151.1\|580963_581206_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_001299351.1\|581183_582203_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_000375128.1\|582610_583270_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	1.8e-48	55.3
585034:585049	attR	NA	NA	NA	NA

DBSCAN-SWA_5

871314 : 909408

Enterobacteria_phage(50.0%)

portal,terminase,lysis,tail,holin,integrase,protease

attL 870899:870913|attR 909482:909496

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
870899:870913	attL	NA	NA	NA	NA
WP_001247925.1\|871314_872013_-\|protease	T3SS effector zinc metalloprotease NleD	NA	NA	NA	NA
WP_151121011.1\|872079_872268_+	hypothetical protein	NA	NA	NA	NA
WP_072127173.1\|873292_873454_-\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	3.9e-13	72.5
WP_115801843.1\|873950_874970_-\|protease	type III secretion system effector zinc metalloprotease NleC	NA	NA	NA	NA
WP_000950813.1\|875003_875984_-	type III secretion system effector arginine glycosyltransferase NleB2	Q8HAB2	Salmonella_phage	2.9e-87	49.5
WP_001024022.1\|876160_876430_-\|tail	phage tail protein	A0A1I9LJT0	Stx_converting_phage	4.9e-45	98.9
WP_000741879.1\|876431_877748_-\|tail	tail fiber protein	Q6H9S9	Enterobacteria_phage	2.0e-67	95.6
WP_001233141.1\|877807_878407_-	outer membrane protein	H6WZM8	Escherichia_phage	1.8e-103	92.5
WP_000515426.1\|878477_881891_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	97.1
WP_000090841.1\|881951_882560_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.4e-100	94.1
WP_000194779.1\|882496_883240_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.0e-149	97.6
WP_001152360.1\|883245_883944_-\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	3.9e-134	99.1
WP_000447253.1\|883953_884283_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	1.7e-60	100.0
WP_000371994.1\|884282_887348_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	0.0e+00	98.9
WP_001161009.1\|887319_887649_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
WP_001300035.1\|887657_888044_-\|tail	phage minor tail protein G	A0A291AWW5	Escherichia_phage	1.6e-65	100.0
WP_000211123.1\|888104_888848_-\|tail	phage tail protein	A5LH35	Enterobacteria_phage	9.5e-131	98.0
WP_001079422.1\|888858_889260_-\|tail	tail protein	A5LH34	Enterobacteria_phage	2.0e-71	98.5
WP_000677094.1\|889256_889835_-\|tail	phage tail protein	A5LH33	Enterobacteria_phage	6.1e-101	99.0
WP_001283153.1\|889846_890122_-	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
WP_001097050.1\|890114_890438_-	DUF2190 family protein	A0A291AWX2	Escherichia_phage	8.5e-52	100.0
WP_001136597.1\|890524_892552_-\|protease	Clp protease ClpP	K7PGT6	Enterobacteria_phage	0.0e+00	99.4
WP_151121012.1\|892496_892832_-\|portal	phage portal protein	A5LH29	Enterobacteria_phage	3.5e-56	98.2
WP_010904538.1\|892953_894078_-\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	5.4e-194	99.4
WP_001072975.1\|894005_894218_-	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_000934137.1\|894214_896317_-\|terminase	phage terminase large subunit family protein	A0A291AWY5	Escherichia_phage	0.0e+00	96.7
WP_000349509.1\|896316_896808_-	DUF1441 family protein	A0A291AWV8	Escherichia_phage	1.3e-72	87.2
WP_001303851.1\|896797_897076_-	hypothetical protein	NA	NA	NA	NA
WP_001139679.1\|897482_897635_-	hypothetical protein	K7PKL2	Enterobacteria_phage	8.9e-20	96.0
WP_000092302.1\|897622_898090_-\|lysis	lysis protein	A0A291AWW3	Escherichia_phage	9.4e-76	97.4
WP_000075107.1\|898086_898584_-	lysozyme	A0A1B5FP97	Escherichia_phage	7.1e-90	98.2
WP_000284524.1\|898583_898799_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_012578864.1\|898941_899340_+	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000499454.1\|899420_899579_-	DUF3927 domain-containing protein	NA	NA	NA	NA
WP_001302581.1\|899664_900408_-	hypothetical protein	NA	NA	NA	NA
WP_001097238.1\|900591_901281_-	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.5e-58	48.1
WP_032160865.1\|901295_901418_-	YlcG family protein	NA	NA	NA	NA
WP_000750155.1\|901754_902714_+	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_001028854.1\|902925_903591_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001108055.1\|903587_904208_-	recombination protein NinG	Q716C3	Shigella_phage	1.6e-94	96.1
WP_000567001.1\|904200_904371_-	protein ninF	Q716C4	Shigella_phage	7.9e-25	96.4
WP_001254218.1\|904367_904550_-	NinE family protein	Q8H9Z6	Enterobacteria_phage	4.8e-28	96.7
WP_000186844.1\|905247_905928_+	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	3.5e-132	99.6
WP_000682316.1\|905924_906107_+	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	4.1e-27	95.0
WP_000548536.1\|906079_906271_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	1.1e-25	96.8
WP_023436627.1\|906281_906563_+	hypothetical protein	A0A0P0ZE02	Stx2-converting_phage	1.6e-46	97.8
WP_000763363.1\|906661_906883_+	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	6.4e-35	98.6
WP_000120056.1\|907093_907696_-	hypothetical protein	NA	NA	NA	NA
WP_071525073.1\|907820_908006_-	hypothetical protein	NA	NA	NA	NA
WP_000545728.1\|907938_908106_+	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	1.3e-27	98.2
WP_001303849.1\|908145_908364_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_024219169.1\|908526_909408_+\|integrase	tyrosine-type recombinase/integrase	K7P6P6	Enterobacteria_phage	7.2e-162	99.7
909482:909496	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1452527 : 1504130

Enterobacteria_phage(34.78%)

transposase,integrase,tail

attL 1445684:1445700|attR 1501576:1501592

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1445684:1445700	attL	NA	NA	NA	NA
WP_000998048.1\|1452527_1454066_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|1454115_1454463_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|1454459_1454840_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000803998.1\|1455103_1455367_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_000866436.1\|1455366_1455507_+	50S ribosomal protein L36	NA	NA	NA	NA
WP_001147284.1\|1455576_1455768_-	hypothetical protein	NA	NA	NA	NA
WP_001303810.1\|1455829_1456120_-	hypothetical protein	NA	NA	NA	NA
WP_000389022.1\|1456592_1457135_+	ECP biosynthesis operon DNA-binding transcriptional regulator EcpR	NA	NA	NA	NA
WP_000730972.1\|1457209_1457797_+	common pilus major fimbrillin subunit EcpA	NA	NA	NA	NA
WP_000716386.1\|1457854_1458523_+	fimbrial chaperone EcpB	NA	NA	NA	NA
WP_001131063.1\|1458548_1461074_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_001265657.1\|1461063_1462707_+	fimbrial adhesin EcpD	NA	NA	NA	NA
WP_001301550.1\|1462675_1463386_+	fimbrial chaperone EcpE	NA	NA	NA	NA
WP_001303809.1\|1463698_1464028_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_001019920.1\|1464275_1464890_-	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_000070685.1\|1465307_1465997_+	aldehyde dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_000643341.1\|1465993_1466950_+	xanthine dehydrogenase family protein subunit M	NA	NA	NA	NA
WP_000667043.1\|1466946_1469145_+	xanthine dehydrogenase family protein molybdopterin-binding subunit	A0A0P0I429	Acinetobacter_phage	1.5e-38	25.7
WP_000121321.1\|1469154_1470111_+	molybdenum cofactor insertion chaperone PaoD	NA	NA	NA	NA
WP_000171064.1\|1470289_1471417_-	MFS transporter	NA	NA	NA	NA
WP_001303808.1\|1471558_1472617_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_010917758.1\|1472862_1473765_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001301751.1\|1474467_1474746_-	hypothetical protein	NA	NA	NA	NA
WP_000361969.1\|1474912_1475635_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000687183.1\|1475733_1476633_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000205213.1\|1477308_1478265_+	hypothetical protein	NA	NA	NA	NA
WP_000016225.1\|1478397_1480731_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	72.5
WP_000562750.1\|1480744_1481068_-	endopeptidase ClpB	NA	NA	NA	NA
WP_001071227.1\|1481067_1481289_-	hypothetical protein	NA	NA	NA	NA
WP_000973389.1\|1481285_1481843_-	ash family protein	Q7M2A7	Enterobacteria_phage	9.3e-30	64.9
WP_001244581.1\|1481839_1482100_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	1.3e-23	65.1
WP_000154958.1\|1483033_1483786_+	septation initiation protein	NA	NA	NA	NA
WP_000968317.1\|1483782_1484334_+	Polarity suppression protein	NA	NA	NA	NA
WP_001185340.1\|1484339_1484612_+	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_100068595.1\|1484759_1484963_+	hypothetical protein	NA	NA	NA	NA
WP_000350115.1\|1485021_1485588_-	hypothetical protein	NA	NA	NA	NA
WP_000695296.1\|1485587_1485791_-	hypothetical protein	NA	NA	NA	NA
WP_000647286.1\|1485787_1486177_-	hypothetical protein	NA	NA	NA	NA
WP_001457442.1\|1486353_1486839_-	AAA family ATPase	NA	NA	NA	NA
WP_000251694.1\|1486831_1487290_-	hypothetical protein	NA	NA	NA	NA
WP_001303996.1\|1487289_1487907_-	hypothetical protein	NA	NA	NA	NA
WP_000082144.1\|1487879_1488296_-	hypothetical protein	NA	NA	NA	NA
WP_001130487.1\|1488299_1489481_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	2.4e-144	61.3
WP_000355475.1\|1492009_1492783_+	hypothetical protein	A0A289ZIY5	Serratia_phage	5.0e-50	44.7
WP_000904979.1\|1492840_1493395_-	site-specific DNA recombinase	A0A0F7LA37	Escherichia_phage	2.8e-87	88.4
WP_001115553.1\|1493424_1493835_+\|tail	tail fiber protein	A0A0F7LBW5	Escherichia_phage	2.2e-65	97.6
WP_000344820.1\|1493855_1494299_+\|tail	tail assembly chaperone	A0A0F7LDZ0	Escherichia_phage	7.0e-81	97.3
WP_000805544.1\|1494270_1494864_-\|tail	tail assembly protein	Q9MCR5	Enterobacteria_phage	5.2e-55	61.7
WP_001096963.1\|1494863_1495658_-\|tail	tail fiber protein	K7PH60	Enterobacterial_phage	2.8e-80	92.9
WP_000788819.1\|1495657_1495969_-	hypothetical protein	A0A0M5M1K4	Salmonella_phage	9.7e-29	73.2
WP_000251069.1\|1496920_1497214_-	hypothetical protein	A2SY75	Escherichia_phage	3.7e-46	100.0
WP_000437875.1\|1497332_1497533_-	hypothetical protein	A4KWT7	Enterobacteria_phage	4.3e-30	100.0
WP_001274756.1\|1497633_1498347_+	LexA family transcriptional regulator	A4KWV9	Enterobacteria_phage	3.5e-130	99.2
WP_000708838.1\|1498474_1498864_+	hypothetical protein	A0A0R6PGY5	Moraxella_phage	1.7e-06	36.3
WP_001303805.1\|1499103_1499349_+	transcription antitermination protein	J3JZZ6	Escherichia_phage	1.0e-12	90.5
WP_000893282.1\|1500418_1501672_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	3.4e-96	47.2
1501576:1501592	attR	NA	NA	NA	NA
WP_001285288.1\|1501683_1502787_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000749881.1\|1503074_1504130_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	7.7e-118	60.9

DBSCAN-SWA_7

1522916 : 1545614

uncultured_Caudovirales_phage(50.0%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000027427.1\|1522916_1524089_-\|transposase	ISAs1-like element ISEc26 family transposase	NA	NA	NA	NA
WP_120795385.1\|1524169_1524355_+	protein YncO	NA	NA	NA	NA
WP_000247943.1\|1524269_1524533_-	hypothetical protein	NA	NA	NA	NA
WP_001145876.1\|1524734_1526495_-	RHS repeat protein	A0A2H4JHK7	uncultured_Caudovirales_phage	1.0e-21	42.3
WP_000420837.1\|1526497_1527634_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_001303801.1\|1527741_1528032_-	hypothetical protein	NA	NA	NA	NA
WP_001356493.1\|1528379_1528925_-	sel1 repeat family protein	NA	NA	NA	NA
WP_000103125.1\|1533282_1535424_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	4.1e-25	25.0
WP_001142958.1\|1535633_1536152_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000037399.1\|1536848_1537349_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000123970.1\|1537383_1537608_+	hypothetical protein	NA	NA	NA	NA
WP_000056994.1\|1537658_1539050_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000599596.1\|1539140_1539554_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000393844.1\|1539557_1541408_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000348794.1\|1541371_1542454_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_001113707.1\|1542478_1543759_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_001080153.1\|1543755_1544280_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_000246434.1\|1544282_1545614_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_8

3761564 : 3785011

Stx2-converting_phage(35.29%)

holin,transposase,integrase,tail

attL 3753211:3753225|attR 3785882:3785896

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3753211:3753225	attL	NA	NA	NA	NA
WP_000540864.1\|3761564_3762770_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_000428092.1\|3762771_3764085_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001059531.1\|3764081_3765713_+	DNA-binding protein	NA	NA	NA	NA
WP_001052051.1\|3765713_3766112_+	hypothetical protein	NA	NA	NA	NA
WP_000361847.1\|3766209_3766623_+	hypothetical protein	NA	NA	NA	NA
WP_000150586.1\|3767018_3768203_+	hypothetical protein	NA	NA	NA	NA
WP_001417601.1\|3768278_3768581_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_001254939.1\|3768616_3769372_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_001108081.1\|3769719_3770286_+	HNH endonuclease	A0A1U9AJK5	Stx1_converting_phage	2.3e-108	100.0
WP_001223948.1\|3770260_3770872_+	protein ninG	A0A1U9AJF8	Stx1_converting_phage	2.5e-92	95.6
WP_001028854.1\|3770868_3771534_+	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001235472.1\|3771530_3772154_+	antitermination protein	K7PM87	Enterobacteria_phage	2.2e-112	98.1
WP_001302581.1\|3772406_3773150_+	hypothetical protein	NA	NA	NA	NA
WP_000499458.1\|3773235_3773403_+	DUF3927 domain-containing protein	NA	NA	NA	NA
WP_000143065.1\|3773810_3775664_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	97.9
WP_000284517.1\|3775813_3776029_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000731241.1\|3776033_3776378_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.7e-58	99.1
WP_001171554.1\|3776734_3777115_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|3777111_3777459_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998000.1\|3777508_3778153_+\|transposase	transposase	A0A0P0ZBS5	Stx2-converting_phage	1.8e-69	100.0
WP_001299612.1\|3777959_3778850_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	5.6e-170	100.0
WP_000165061.1\|3778846_3779173_-\|transposase	transposase	A0A0N7BVE9	Escherichia_phage	1.3e-55	100.0
WP_001023396.1\|3779390_3779660_+\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	3.8e-45	100.0
WP_000442132.1\|3779820_3780243_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	5.7e-72	97.0
WP_001301665.1\|3780372_3781431_-	T3SS effector EspW	NA	NA	NA	NA
WP_001144077.1\|3781509_3782160_-	DUF1076 domain-containing protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
WP_001132157.1\|3782342_3782933_+	T3SS effector guanine nucleotide exchange factor EspM2	NA	NA	NA	NA
WP_001302510.1\|3782919_3783039_-	hypothetical protein	NA	NA	NA	NA
WP_001217542.1\|3783434_3783683_-	DNA damage-inducible protein DinI	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_000162574.1\|3784528_3785011_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
3785882:3785896	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4062626 : 4068013

Enterobacteria_phage(50.0%)

integrase

attL 4051576:4051592|attR 4070209:4070225

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4051576:4051592	attL	NA	NA	NA	NA
WP_001005794.1\|4062626_4063157_+	hypothetical protein	Q716G6	Shigella_phage	5.7e-69	99.3
WP_000403517.1\|4063156_4063624_+	DUF2824 family protein	Q2A0B3	Sodalis_phage	1.7e-64	74.7
WP_000960724.1\|4063610_4064291_+	DNA transfer protein	G5DA80	Enterobacteria_phage	1.8e-59	71.0
WP_000257010.1\|4064300_4065437_+	acyltransferase	Q716G3	Shigella_phage	1.4e-80	72.8
WP_000958700.1\|4065611_4066769_-\|integrase	prophage integrase IntS	E7DYQ6	Enterobacteria_phage	2.2e-222	100.0
WP_000368131.1\|4067080_4068013_-	transporter	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
4070209:4070225	attR	NA	NA	NA	NA

DBSCAN-SWA_10

4314945 : 4392503

Enterobacteria_phage(63.1%)

portal,tRNA,terminase,transposase,tail,holin,integrase,protease

attL 4317420:4317440|attR 4366608:4366628

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569336.1\|4314945_4315872_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	4.8e-23	30.8
WP_000783120.1\|4315876_4316608_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|4316588_4316696_-	protein YohO	NA	NA	NA	NA
WP_027868261.1\|4316755_4317457_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.6e-103	100.0
4317420:4317440	attL	NA	NA	NA	NA
WP_000063648.1\|4317477_4318764_-\|integrase	site-specific integrase	Q9EY96	Enterobacteria_phage	7.6e-253	100.0
WP_149008366.1\|4318797_4319040_-	hypothetical protein	Q859D3	Escherichia_coli_phage	9.6e-16	86.0
WP_085948178.1\|4318962_4320175_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000556583.1\|4320384_4320519_-	hypothetical protein	A0A0P0ZDP5	Stx2-converting_phage	4.9e-22	100.0
WP_000457728.1\|4320522_4320765_-	DUF4222 domain-containing protein	B6DZ51	Enterobacteria_phage	1.5e-37	100.0
WP_000610375.1\|4320852_4321215_-	DUF551 domain-containing protein	Q9EY98	Enterobacteria_phage	1.8e-71	100.0
WP_000207903.1\|4321211_4321568_-	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	3.1e-63	100.0
WP_001113545.1\|4321644_4321932_-	hypothetical protein	NA	NA	NA	NA
WP_001356547.1\|4321901_4322078_-	hypothetical protein	B6DZ55	Enterobacteria_phage	4.6e-28	100.0
WP_001289954.1\|4322079_4323027_-	ead/Ea22-like family protein	A0A0P0ZE96	Stx2-converting_phage	3.6e-183	100.0
WP_000763383.1\|4323023_4323245_-	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.9e-35	100.0
WP_001444000.1\|4323343_4323625_-	cell division protein ZapA	A0A0P0ZBQ0	Stx2-converting_phage	1.9e-47	100.0
WP_000548547.1\|4323635_4323827_-	DUF1382 family protein	A0A1I9LJM8	Stx_converting_phage	1.9e-27	100.0
WP_001303590.1\|4323799_4323982_-	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	7.4e-29	100.0
WP_000186740.1\|4323981_4324659_-	YqaJ viral recombinase family protein	A0A1I9LJM9	Stx_converting_phage	4.6e-132	100.0
WP_000100847.1\|4324655_4325441_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995395.1\|4325446_4325743_-	host-nuclease inhibitor protein Gam	Q9EYA6	Enterobacteria_phage	4.3e-50	100.0
WP_001478900.1\|4325711_4325864_-	hypothetical protein	Q08J51	Stx2-converting_phage	3.6e-21	98.0
WP_000372942.1\|4325818_4325962_-	host cell division inhibitory peptide Kil	Q9EYA7	Enterobacteria_phage	1.2e-18	100.0
WP_001198861.1\|4325930_4326095_-\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	1.1e-26	100.0
WP_000065377.1\|4326167_4326536_-	DUF2528 family protein	A0A1I9LJN3	Stx_converting_phage	7.6e-65	100.0
WP_001066169.1\|4326796_4327378_+	superinfection exclusion protein B	Q9EYA9	Enterobacteria_phage	4.0e-100	100.0
WP_000256574.1\|4327394_4327667_-	hypothetical protein	Q9EYB0	Enterobacteria_phage	2.0e-41	100.0
WP_000990548.1\|4328179_4328731_-	hypothetical protein	A4KWR1	Enterobacteria_phage	4.1e-70	100.0
WP_001280993.1\|4328737_4329019_-	hypothetical protein	A4KWR2	Enterobacteria_phage	1.1e-44	100.0
WP_001299796.1\|4329141_4329789_-	LexA family transcriptional regulator	K7PH19	Enterobacteria_phage	1.2e-121	100.0
WP_001033078.1\|4329897_4330116_+	helix-turn-helix transcriptional regulator	K7PKH4	Enterobacteria_phage	1.1e-34	100.0
WP_000035953.1\|4330230_4330527_+	hypothetical protein	Q9EYB4	Enterobacteria_phage	1.8e-48	100.0
WP_000788906.1\|4331487_4332189_+	Replication protein 14	Q9EYB6	Enterobacteria_phage	5.8e-130	100.0
WP_000145935.1\|4332185_4332476_+	protein ren	A0A0P0ZCJ0	Stx2-converting_phage	9.6e-47	100.0
WP_001000130.1\|4332546_4332825_+	hypothetical protein	Q9EYB9	Enterobacteria_phage	4.4e-49	100.0
WP_000103678.1\|4332957_4333173_+	hypothetical protein	A0A0N7KZ98	Stx2-converting_phage	7.7e-33	100.0
WP_001281772.1\|4333183_4333420_+	restriction alleviation protein, Lar family	Q8HA09	Enterobacteria_phage	1.2e-39	100.0
WP_001304104.1\|4333376_4333823_+	recombination protein NinB	A0A1I9LJP8	Stx_converting_phage	2.4e-81	100.0
WP_000153268.1\|4333819_4334347_+	phage N-6-adenine-methyltransferase	Q9EYC2	Enterobacteria_phage	1.6e-100	100.0
WP_001254255.1\|4334343_4334520_+	NinE family protein	A5VW90	Enterobacteria_phage	4.6e-28	100.0
WP_000924601.1\|4334522_4334924_+	hypothetical protein	Q9EYC4	Enterobacteria_phage	1.4e-72	100.0
WP_001543885.1\|4334883_4335093_+	protein ninF	G9L691	Escherichia_phage	3.5e-30	97.1
WP_001107983.1\|4335085_4335691_+	recombination protein NinG	Q9EYC6	Enterobacteria_phage	2.3e-98	100.0
WP_000144764.1\|4335687_4335882_+	protein ninH	G9L694	Escherichia_phage	1.9e-30	100.0
WP_001204849.1\|4335874_4336309_+	antitermination protein	Q8VNP1	Enterobacteria_phage	4.3e-83	100.0
WP_015971135.1\|4336297_4336543_-	hypothetical protein	A0A0P0ZGS0	Escherichia_phage	5.0e-36	100.0
WP_000691354.1\|4336815_4337763_+	Shiga toxin Stx1 subunit A	Q777W4	Enterobacteria_phage	3.2e-171	100.0
WP_000752026.1\|4337772_4338042_+	Shiga toxin Stx1a subunit B	Q7AYI7	Enterobacteria_phage	1.6e-43	100.0
WP_042817377.1\|4338102_4338435_-	hypothetical protein	Q8VNP0	Enterobacteria_phage	2.1e-58	99.1
WP_000874257.1\|4338552_4340499_+	DUF1737 domain-containing protein	Q9EYC8	Enterobacteria_phage	0.0e+00	100.0
WP_000143458.1\|4340636_4340816_+	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_001290230.1\|4340856_4341102_+	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_000284506.1\|4341179_4341395_+\|holin	holin	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_000087728.1\|4341399_4341933_+	lysozyme	A0A1I9LJR4	Stx_converting_phage	1.8e-102	100.0
WP_001056806.1\|4342203_4342773_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|4342772_4342919_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_012816791.1\|4343146_4343332_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_001302882.1\|4343543_4343816_-	hypothetical protein	NA	NA	NA	NA
WP_000348565.1\|4343848_4344325_+	DUF1441 family protein	Q9EYD0	Enterobacteria_phage	2.1e-83	100.0
WP_001077625.1\|4344321_4346445_+\|terminase	phage terminase large subunit family protein	Q9EYD1	Enterobacteria_phage	0.0e+00	100.0
WP_000102414.1\|4346441_4346654_+	hypothetical protein	S5MBY8	Escherichia_phage	1.1e-28	97.1
WP_000974564.1\|4346653_4348156_+\|portal	phage portal protein	Q9EYD2	Enterobacteria_phage	4.8e-291	100.0
WP_001356427.1\|4348169_4349060_+\|protease	Clp protease ClpP	Q9EYD3	Enterobacteria_phage	5.8e-167	100.0
WP_085948178.1\|4349062_4350276_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000502242.1\|4350397_4351438_+	peptidase	Q8VNN5	Enterobacteria_phage	5.9e-195	99.7
WP_001097065.1\|4351525_4351852_+	DUF2190 family protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
WP_001281350.1\|4351844_4352126_+	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	3.9e-45	97.8
WP_000974966.1\|4352128_4352752_+	hypothetical protein	Q9EYD6	Enterobacteria_phage	6.6e-101	100.0
WP_000682716.1\|4352764_4353163_+\|tail	tail protein	Q9EYD7	Enterobacteria_phage	5.9e-71	100.0
WP_000235090.1\|4353170_4353923_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
WP_000479043.1\|4353936_4354359_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	5.1e-73	100.0
WP_000532073.1\|4354385_4354694_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	1.3e-54	100.0
WP_000918269.1\|4354737_4357383_+\|tail	phage tail tape measure protein	Q9EYE1	Enterobacteria_phage	0.0e+00	100.0
WP_000847298.1\|4357379_4357709_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_115448574.1\|4357708_4358407_+\|tail	phage minor tail protein L	Q9EYE3	Enterobacteria_phage	2.8e-132	98.7
WP_000194798.1\|4358417_4359161_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	3.7e-151	100.0
WP_072147834.1\|4359106_4359736_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-110	99.5
WP_151121034.1\|4359976_4363450_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	90.3
WP_001228289.1\|4363517_4364117_+	Ail/Lom family protein	Q9EV15	Enterobacteria_phage	2.6e-110	100.0
WP_000268835.1\|4364181_4365495_+\|tail	tail fiber protein	Q9EYE8	Enterobacteria_phage	8.8e-79	100.0
WP_001023431.1\|4365496_4365766_+\|tail	phage tail protein	Q9EYE9	Enterobacteria_phage	2.9e-45	100.0
WP_001261937.1\|4366133_4366382_-	DinI family protein	Q687E4	Enterobacteria_phage	9.1e-38	97.6
WP_001301761.1\|4366896_4368582_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	1.7e-305	100.0
4366608:4366628	attR	NA	NA	NA	NA
WP_000598641.1\|4368578_4369298_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295430.1\|4369344_4369815_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001295429.1\|4369856_4370318_-	DUF1307 domain-containing protein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_085953806.1\|4370501_4371714_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	8.4e-169	99.3
WP_001302810.1\|4373755_4374892_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.9e-167	100.0
WP_000528951.1\|4374884_4375616_-	hypothetical protein	NA	NA	NA	NA
WP_001294377.1\|4375634_4377164_-	hypothetical protein	NA	NA	NA	NA
WP_001302026.1\|4377174_4378263_-	MoxR family ATPase	NA	NA	NA	NA
WP_000636932.1\|4379503_4379821_-	hypothetical protein	NA	NA	NA	NA
WP_000356841.1\|4379882_4383512_-	DUF4132 domain-containing protein	NA	NA	NA	NA
WP_122989774.1\|4383521_4385063_-	DUF4132 domain-containing protein	NA	NA	NA	NA
WP_001411921.1\|4385226_4386507_-	WGR domain-containing protein	NA	NA	NA	NA
WP_001301615.1\|4390469_4392503_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.4e-54	27.6

DBSCAN-SWA_11

4519459 : 4593171

Escherichia_phage(35.42%)

head,portal,terminase,transposase,tail,holin,integrase

attL 4546219:4546278|attR 4570323:4571633

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085952406.1\|4519459_4520673_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	1.8e-163	97.3
WP_000966626.1\|4521044_4523192_-	TonB-dependent receptor	NA	NA	NA	NA
WP_071525094.1\|4523298_4523481_-	hypothetical protein	NA	NA	NA	NA
WP_000998048.1\|4524639_4526178_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|4526227_4526575_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|4526571_4526952_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000973176.1\|4527313_4527859_+	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	NA	NA	NA	NA
WP_001295633.1\|4527855_4528599_+	adenosylcobinamide-GDP ribazoletransferase	NA	NA	NA	NA
WP_001193830.1\|4528610_4529690_+	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	NA	NA	NA	NA
WP_000986334.1\|4529751_4530687_+	L,D-transpeptidase	NA	NA	NA	NA
WP_001011474.1\|4531143_4532061_+	nitrogen assimilation transcriptional regulator	NA	NA	NA	NA
WP_001011000.1\|4532162_4533113_+	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_000532909.1\|4535499_4536216_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_001060244.1\|4536558_4538013_-	AMP nucleosidase	NA	NA	NA	NA
WP_000378596.1\|4538114_4539431_-	shikimate transporter	NA	NA	NA	NA
WP_000480501.1\|4539744_4540797_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
4546219:4546278	attL	NA	NA	NA	NA
WP_085948178.1\|4546272_4547485_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001302302.1\|4550843_4551641_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_000533600.1\|4551876_4552899_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	2.0e-99	57.4
WP_000094838.1\|4552898_4553102_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_000034457.1\|4553160_4555632_-	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_000199485.1\|4555727_4555916_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449168.1\|4555912_4556101_-	cell division inhibitor	NA	NA	NA	NA
WP_000367376.1\|4556581_4556734_-	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	8.7e-07	53.2
WP_000444607.1\|4557008_4557653_-	LexA family transcriptional regulator	A0A1P8DTH0	Proteus_phage	2.8e-06	24.9
WP_001261752.1\|4557750_4557978_+	cell division protein	NA	NA	NA	NA
WP_000693816.1\|4557974_4558400_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001262409.1\|4558468_4559506_+	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.1e-87	68.3
WP_000373320.1\|4559537_4559960_+	hypothetical protein	A0A0U2JGJ0	Escherichia_phage	5.0e-76	96.4
WP_000450610.1\|4559994_4560693_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.6e-71	59.5
WP_000702797.1\|4560714_4560939_+	hypothetical protein	A0A1B5FPG2	Escherichia_phage	3.6e-09	42.3
WP_001290006.1\|4560935_4561292_+	hypothetical protein	A0A222YY85	Escherichia_phage	3.1e-15	65.8
WP_001414276.1\|4561324_4561477_+	hypothetical protein	NA	NA	NA	NA
WP_000111243.1\|4561473_4561785_+	hypothetical protein	A0A222YY67	Escherichia_phage	2.4e-51	83.5
WP_000137954.1\|4561911_4562475_+	hypothetical protein	H6WZG0	Escherichia_phage	4.5e-48	94.9
WP_001278460.1\|4562584_4562689_+	hypothetical protein	NA	NA	NA	NA
WP_000902687.1\|4562875_4563088_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	7.6e-25	90.0
WP_001302544.1\|4563129_4563315_-	hypothetical protein	NA	NA	NA	NA
WP_001310296.1\|4563255_4563534_+	hypothetical protein	I6PCV7	Cronobacter_phage	1.3e-11	48.4
WP_001265075.1\|4563535_4564585_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.3e-109	54.9
WP_000904141.1\|4564597_4564957_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.5e-36	64.9
WP_001059369.1\|4564953_4565643_+	antiterminator	I6PDF8	Cronobacter_phage	1.5e-58	51.1
WP_001302069.1\|4565673_4565796_+	hypothetical protein	NA	NA	NA	NA
WP_001303558.1\|4566276_4566705_+	tellurite resistance protein	H6WZJ6	Escherichia_phage	4.9e-63	96.4
WP_000023257.1\|4567182_4569033_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.4
WP_085948178.1\|4569114_4570328_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000411809.1\|4570647_4570854_+\|holin	holin	Q6H9V8	Enterobacteria_phage	2.4e-31	100.0
WP_000731204.1\|4570858_4571203_+	YdfR family protein	B6DZ91	Enterobacteria_phage	1.7e-58	99.1
WP_000992126.1\|4571253_4571787_+	lysozyme	A0A0N7KZF9	Stx2-converting_phage	1.4e-99	97.7
4570323:4571633	attR	NA	NA	NA	NA
WP_001303555.1\|4571942_4572125_+	hypothetical protein	NA	NA	NA	NA
WP_001280929.1\|4572137_4572269_+	hypothetical protein	A0A0N7BYT9	Escherichia_phage	9.4e-10	88.4
WP_001208680.1\|4572496_4572682_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_001302690.1\|4573208_4573523_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001299328.1\|4573604_4573829_-	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	4.1e-21	92.7
WP_000235436.1\|4574223_4574733_+\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001302857.1\|4574704_4576633_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	3.3e-260	65.9
WP_000259002.1\|4576616_4576823_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_000831796.1\|4576819_4578412_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.7e-182	60.5
WP_001254002.1\|4578401_4579907_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-100	54.2
WP_000256723.1\|4579943_4580291_+\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.6e-22	58.1
WP_001301534.1\|4580348_4580615_+	hypothetical protein	NA	NA	NA	NA
WP_029208397.1\|4580596_4581337_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.6e-130	98.0
WP_000479117.1\|4581350_4581782_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	68.1
WP_000533402.1\|4581808_4582222_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_151121036.1\|4582202_4584782_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	81.6
WP_000847298.1\|4584778_4585108_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_115448574.1\|4585107_4585806_+\|tail	phage minor tail protein L	Q9EYE3	Enterobacteria_phage	2.8e-132	98.7
WP_000194798.1\|4585816_4586560_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	3.7e-151	100.0
WP_072147834.1\|4586505_4587135_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-110	99.5
WP_149888716.1\|4587375_4590855_+	DUF1983 domain-containing protein	B6DZB5	Enterobacteria_phage	0.0e+00	99.1
WP_001230508.1\|4590922_4591522_+	outer membrane protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_070479928.1\|4591586_4592900_+\|tail	phage tail protein	A0A0P0ZE15	Stx2-converting_phage	4.8e-77	97.0
WP_001023407.1\|4592901_4593171_+\|tail	phage tail protein	H6WZN0	Escherichia_phage	1.4e-44	98.9

DBSCAN-SWA_12

4970152 : 5084405

143

Escherichia_phage(28.18%)

portal,head,terminase,transposase,tail,holin,capsid,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001260835.1\|4970152_4970974_-\|protease	serine protease	NA	NA	NA	NA
WP_000233090.1\|4971073_4971157_-	hypothetical protein	NA	NA	NA	NA
WP_000743952.1\|4971249_4971585_-	acid shock protein	NA	NA	NA	NA
WP_000091829.1\|4971981_4973235_-	MFS transporter	NA	NA	NA	NA
WP_001019530.1\|4973341_4974235_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000225276.1\|4974369_4975590_+	DNA-binding transcriptional repressor Mlc	NA	NA	NA	NA
WP_000919231.1\|4975714_4976410_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_071525082.1\|4976362_4977655_-	voltage-gated ClC-type chloride channel ClcB	NA	NA	NA	NA
WP_000148710.1\|4977812_4978427_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	8.7e-29	36.3
WP_000526515.1\|4978469_4979324_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_000213028.1\|4979325_4979943_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	9.5e-76	59.6
WP_001414236.1\|4979953_4982377_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.3e-208	48.6
WP_000041704.1\|4982437_4984864_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.1e-212	49.0
WP_000778147.1\|4985062_4985368_-	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_001303515.1\|4985475_4986186_+	YnfC family lipoprotein	NA	NA	NA	NA
WP_001138581.1\|4986188_4986749_-	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_000705189.1\|4986783_4987125_-	DUF1283 family protein	NA	NA	NA	NA
WP_001302046.1\|4987259_4987586_+	YnfA family protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
WP_000546375.1\|4987758_4987884_+	hypothetical protein	NA	NA	NA	NA
WP_001296941.1\|4988574_4988811_-	excisionase family protein	S4TND0	Salmonella_phage	6.1e-15	50.7
WP_000048458.1\|4988898_4991370_-	exonuclease	K7PLW7	Enterobacteria_phage	3.2e-58	60.1
WP_001090200.1\|4991462_4991654_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449192.1\|4991650_4991839_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001331716.1\|4992239_4992404_+	hypothetical protein	NA	NA	NA	NA
WP_001171930.1\|4992407_4992626_-	hypothetical protein	NA	NA	NA	NA
WP_001240334.1\|4992697_4992997_-	hypothetical protein	NA	NA	NA	NA
WP_001303511.1\|4993349_4993628_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001302048.1\|4993629_4993821_-	hypothetical protein	NA	NA	NA	NA
WP_001169686.1\|4993841_4994213_-	hypothetical protein	NA	NA	NA	NA
WP_000172738.1\|4994310_4994613_+	transcriptional regulator	K7PHA1	Enterobacteria_phage	8.6e-06	34.8
WP_000693943.1\|4994609_4995035_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000095669.1\|4995057_4996020_+	DNA-binding protein	U5P0A0	Shigella_phage	4.8e-82	57.3
WP_000788938.1\|4996026_4996767_+	replication protein	A0A088CBP4	Shigella_phage	4.6e-125	90.2
WP_001118159.1\|4997577_4997973_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	7.8e-31	51.4
WP_000206793.1\|4998029_4998614_+	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	1.9e-33	84.8
WP_001278450.1\|4998729_4998834_+	hypothetical protein	NA	NA	NA	NA
WP_000887477.1\|4999022_4999235_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.1e-18	68.6
WP_012779366.1\|4999402_4999681_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265161.1\|4999682_5000732_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.4e-108	53.7
WP_151121037.1\|5000744_5001104_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	4.6e-38	67.5
WP_001059381.1\|5001100_5001790_+	antiterminator	I6PDF8	Cronobacter_phage	4.0e-59	51.1
WP_001302069.1\|5001820_5001943_+	hypothetical protein	NA	NA	NA	NA
WP_001303509.1\|5002429_5002858_+	tellurite resistance protein	H6WZJ6	Escherichia_phage	4.4e-64	97.8
WP_000023202.1\|5003335_5005186_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.4
WP_000411805.1\|5005634_5005841_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.0e-31	98.5
WP_000731259.1\|5005845_5006190_+	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000992137.1\|5006240_5006774_+	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_001056806.1\|5007044_5007614_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|5007613_5007760_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_012816791.1\|5007987_5008173_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000095736.1\|5008597_5008825_-	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_000279786.1\|5008866_5009232_+	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_000958416.1\|5009521_5010085_+\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	4.7e-90	100.0
WP_038425863.1\|5010081_5011743_+\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.8
WP_000173030.1\|5011806_5013744_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	100.0
WP_001063094.1\|5013788_5014010_+	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	1.3e-35	98.6
WP_001304108.1\|5013955_5016535_+\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	97.3
WP_000125988.1\|5016537_5016864_+\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001007905.1\|5016873_5017224_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000573391.1\|5017220_5017667_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133388.1\|5017663_5018008_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_060722693.1\|5018073_5018790_+\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	5.2e-126	97.1
WP_001030063.1\|5018795_5019170_+\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001453698.1\|5019265_5019475_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_000212897.1\|5019527_5022608_+\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	94.2
WP_000807954.1\|5022600_5022942_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_001152128.1\|5022941_5023379_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	6.5e-63	100.0
WP_038425866.1\|5023566_5026827_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	92.1
WP_001304111.1\|5026829_5027045_+	hypothetical protein	Q9LA64	Enterobacterial_phage	1.0e-32	97.2
WP_001230508.1\|5027112_5027712_+	outer membrane protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_001023362.1\|5029002_5029272_+\|tail	phage tail protein	H6WZN0	Escherichia_phage	6.4e-45	98.9
WP_010917823.1\|5030338_5030686_+	hypothetical protein	B6ETE2	Enterobacteria_phage	6.1e-48	96.8
WP_001121225.1\|5030670_5031321_+	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_000998048.1\|5031903_5033442_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|5033491_5033839_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|5033835_5034216_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_016241229.1\|5035178_5035493_-	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_000102123.1\|5036131_5037376_-	exonuclease	H6WRX1	Salmonella_phage	1.4e-86	50.3
WP_000199475.1\|5037468_5037657_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449175.1\|5037653_5037842_-	cell division inhibitor	NA	NA	NA	NA
WP_001133037.1\|5038406_5038616_+	hypothetical protein	NA	NA	NA	NA
WP_000394548.1\|5038616_5039255_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_000380316.1\|5039266_5039419_-	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	5.1e-07	53.2
WP_001416688.1\|5039711_5040050_-	peptidase S24	H9C160	Pectobacterium_phage	1.9e-06	30.1
WP_000747948.1\|5040441_5040684_+	hypothetical protein	H9C161	Pectobacterium_phage	4.8e-07	55.8
WP_000693878.1\|5040667_5041093_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001262402.1\|5041161_5042205_+	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.4e-82	65.1
WP_001379651.1\|5042236_5042659_+	replication protein	A0A0U2JGJ0	Escherichia_phage	5.7e-72	90.0
WP_000450627.1\|5042692_5043409_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	3.3e-72	62.8
WP_000603384.1\|5043441_5043723_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_000699809.1\|5043719_5043947_+	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_001289673.1\|5043939_5044251_+	hypothetical protein	A0A0U2QV73	Escherichia_phage	7.2e-56	92.2
WP_000683609.1\|5044378_5044597_+	DUF4014 domain-containing protein	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
WP_000104474.1\|5044598_5045156_+	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000935259.1\|5045389_5045602_+	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000756596.1\|5045721_5046066_+	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000191872.1\|5046187_5046460_+	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_001265229.1\|5046461_5047511_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.6
WP_001217444.1\|5047523_5047829_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	7.1e-32	66.3
WP_000640035.1\|5047891_5048446_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.0e-65	67.4
WP_000917763.1\|5048670_5048868_+	hypothetical protein	S5MQK8	Escherichia_phage	8.9e-28	96.9
WP_000301797.1\|5049003_5049717_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001303509.1\|5050171_5050600_+	tellurite resistance protein	H6WZJ6	Escherichia_phage	4.4e-64	97.8
WP_000023184.1\|5051077_5052928_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.9
WP_000411805.1\|5053375_5053582_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.0e-31	98.5
WP_000731259.1\|5053586_5053931_+	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000992137.1\|5053981_5054515_+	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_001056806.1\|5054786_5055356_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539795.1\|5055355_5055502_+	hypothetical protein	A0A0P0ZG36	Escherichia_phage	1.1e-11	87.0
WP_001208680.1\|5055724_5055910_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_001302717.1\|5056435_5056750_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001303940.1\|5056831_5057056_-	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	1.7e-19	90.6
WP_032161313.1\|5057071_5057329_-	hypothetical protein	A0A0K2FJC5	Escherichia_phage	1.3e-10	91.4
WP_000867493.1\|5057442_5057988_+\|terminase	terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	4.7e-79	82.8
WP_001027223.1\|5057962_5059888_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	98.1
WP_000198153.1\|5059884_5060091_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001301524.1\|5060087_5061689_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-307	98.7
WP_000123254.1\|5061669_5062989_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.4e-232	98.2
WP_001295978.1\|5062998_5063331_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
WP_000063265.1\|5063386_5064412_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	8.7e-191	98.8
WP_000158906.1\|5064453_5064852_+	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000753016.1\|5064863_5065217_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	1.9e-57	92.3
WP_000975020.1\|5065231_5065765_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-58	66.7
WP_000683063.1\|5065761_5066157_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	3.3e-58	81.7
WP_000235090.1\|5066164_5066917_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
WP_000479046.1\|5066930_5067353_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	2.4e-70	97.9
WP_000533440.1\|5067379_5067793_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_032166593.1\|5067773_5070386_+\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	95.3
WP_000847298.1\|5070382_5070712_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_001151105.1\|5070711_5071410_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	1.2e-130	97.8
WP_000194798.1\|5071420_5072164_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	3.7e-151	100.0
WP_072147834.1\|5072109_5072739_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-110	99.5
WP_151121038.1\|5072979_5076459_+	host specificity protein J	B6DZB5	Enterobacteria_phage	0.0e+00	98.8
WP_001230508.1\|5076526_5077126_+	outer membrane protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_001023362.1\|5078414_5078684_+\|tail	phage tail protein	H6WZN0	Escherichia_phage	6.4e-45	98.9
WP_001131658.1\|5078797_5079373_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-89	88.9
WP_001356599.1\|5079445_5080075_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	6.1e-78	91.5
WP_001143808.1\|5080156_5080798_+	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	8.6e-104	96.2
WP_001480712.1\|5080828_5080963_+	hypothetical protein	NA	NA	NA	NA
WP_016241229.1\|5080959_5081274_-	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_000347470.1\|5081333_5082617_+	MHS family MFS transporter	NA	NA	NA	NA
WP_000527769.1\|5082705_5084166_+	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	1.9e-42	29.6
WP_000214712.1\|5084201_5084405_-	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2

DBSCAN-SWA_13

5258910 : 5316626

Escherichia_phage(40.91%)

head,tRNA,terminase,tail,holin,capsid,integrase

attL 5255368:5255383|attR 5315787:5315802

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5255368:5255383	attL	NA	NA	NA	NA
WP_001295593.1\|5258910_5259345_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
WP_001143784.1\|5259925_5260567_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.8e-109	100.0
WP_001443810.1\|5260648_5261278_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.3e-77	92.2
WP_001131659.1\|5261350_5261926_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	5.3e-89	88.4
WP_001023992.1\|5262038_5262308_-\|tail	phage tail protein	A0A0P0ZCV7	Stx2-converting_phage	4.2e-44	95.5
WP_000268955.1\|5262309_5263623_-\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	9.7e-78	99.1
WP_001230550.1\|5263687_5264287_-	outer membrane protein	B6ETG5	Enterobacteria_phage	3.0e-111	100.0
WP_151121039.1\|5264357_5267855_-	host specificity protein J	A0A0P0ZEQ8	Stx2-converting_phage	0.0e+00	94.2
WP_000649829.1\|5267988_5268516_+	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.8e-59	60.5
WP_010917807.1\|5268546_5268753_-	hypothetical protein	NA	NA	NA	NA
WP_064732755.1\|5268706_5269339_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	3.4e-97	90.4
WP_000194763.1\|5269284_5270028_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.4e-150	99.2
WP_001152159.1\|5270038_5270737_-\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	1.3e-129	97.4
WP_000807964.1\|5270736_5271078_-\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
WP_000212768.1\|5271070_5274151_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	93.3
WP_001453698.1\|5274202_5274412_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030060.1\|5274507_5274882_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	3.0e-64	99.2
WP_001275479.1\|5274887_5275604_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	4.0e-126	97.5
WP_000133393.1\|5275671_5276016_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_000573391.1\|5276012_5276459_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007911.1\|5276455_5276806_-\|head	phage head closure protein	H6WZL5	Escherichia_phage	2.0e-59	100.0
WP_000125984.1\|5276815_5277142_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001063025.1\|5279668_5279890_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_000173011.1\|5279934_5281872_-\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.7
WP_001411753.1\|5281935_5283597_-\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.3
WP_000958380.1\|5283593_5284157_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_000829192.1\|5284445_5284811_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_000095744.1\|5284852_5285053_+	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	1.3e-29	97.0
WP_000828070.1\|5285184_5285511_-	TonB family protein	H6WZK5	Escherichia_phage	6.3e-55	98.1
WP_001412416.1\|5285446_5285629_-	hypothetical protein	H6WZK4	Escherichia_phage	2.2e-25	98.3
WP_077631024.1\|5285619_5285820_-	hypothetical protein	Q9T1L1	Enterobacteria_phage	7.2e-09	71.8
WP_012817877.1\|5285911_5286097_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	4.0e-22	85.2
WP_001280923.1\|5286319_5286451_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	3.8e-11	93.0
WP_000661712.1\|5286545_5287241_-	phage antirepressor protein	Q5MBW0	Stx1-converting_phage	2.8e-124	99.1
WP_000992086.1\|5287514_5288048_-	lysozyme	B6DZ92	Enterobacteria_phage	1.3e-100	97.7
WP_000731221.1\|5288098_5288443_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.8e-55	95.6
WP_000284522.1\|5288447_5288663_-\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
WP_021497500.1\|5288812_5290666_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.3
WP_000466957.1\|5291240_5291672_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_000640158.1\|5292233_5292788_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	5.0e-68	69.1
WP_000247761.1\|5292784_5293075_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-47	87.5
WP_000940319.1\|5293074_5293674_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.1e-105	92.0
WP_000138556.1\|5294173_5295565_+	ATPase	NA	NA	NA	NA
WP_000016656.1\|5295564_5296554_+	hypothetical protein	NA	NA	NA	NA
WP_001100703.1\|5296521_5297673_-	DNA cytosine methyltransferase	Q8JKX6	Natrialba_phage	1.0e-22	36.9
WP_000365100.1\|5298104_5298350_-	hypothetical protein	Q9G078	Enterobacteria_phage	5.9e-13	70.7
WP_000208018.1\|5298428_5298590_-	hypothetical protein	A0A192Y6F5	Salmonella_phage	3.2e-15	89.4
WP_000224233.1\|5298600_5298864_-	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
WP_042350895.1\|5298865_5299030_-	sugar acetyltransferase inhibitor	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
WP_000935420.1\|5299115_5299328_-	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
WP_001141110.1\|5299433_5299856_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	3.1e-62	88.5
WP_000450712.1\|5299871_5300633_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	7.0e-121	90.5
WP_000788980.1\|5300655_5301402_-	replication protein	V5UQI5	Shigella_phage	5.6e-115	81.3
WP_001304174.1\|5301408_5302197_-	hypothetical protein	G9L6A8	Escherichia_phage	2.0e-41	64.3
WP_000693803.1\|5302274_5302697_-	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.3e-68	92.9
WP_001072342.1\|5302693_5302948_-	hypothetical protein	A0A2I6PIE5	Escherichia_phage	1.3e-18	61.6
WP_000233319.1\|5303027_5303447_+	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	5.5e-19	46.5
WP_015695616.1\|5303483_5303702_+	hypothetical protein	NA	NA	NA	NA
WP_000233809.1\|5303734_5303869_+	phage protein	NA	NA	NA	NA
WP_001169151.1\|5303879_5304035_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	6.1e-08	55.3
WP_001312793.1\|5304031_5304520_-	superinfection exclusion protein B	NA	NA	NA	NA
WP_000560223.1\|5304961_5305183_+	killing protein KilR	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
WP_001352098.1\|5305182_5305353_+	conserved protein, Rac prophage	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
WP_000105140.1\|5305803_5308404_+	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	6.1e-249	63.5
WP_000166313.1\|5308396_5309206_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	4.0e-106	71.5
WP_001443846.1\|5309261_5309411_+	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	2.5e-22	95.9
WP_001302840.1\|5309448_5309637_+	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	5.5e-27	98.4
WP_000079604.1\|5309736_5309952_+	excisionase XisR	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
WP_000040839.1\|5309953_5311189_+\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	3.8e-241	99.5
WP_001157407.1\|5311240_5312176_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
WP_000123746.1\|5312304_5313678_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_124056621.1\|5313636_5313867_+	hypothetical protein	NA	NA	NA	NA
WP_000387388.1\|5314155_5315139_-	zinc transporter ZntB	NA	NA	NA	NA
WP_000628061.1\|5315393_5316626_+	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
5315787:5315802	attR	NA	NA	NA	NA

DBSCAN-SWA_14

5401571 : 5477026

Stx2-converting_phage(34.48%)

head,portal,terminase,transposase,tail,holin,capsid,integrase,protease

attL 5417073:5417100|attR 5477163:5477190

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000422055.1\|5401571_5402621_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
WP_000559268.1\|5402840_5403599_+	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	6.7e-07	23.9
WP_001278878.1\|5403595_5404186_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_001291216.1\|5404225_5405098_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001302160.1\|5405310_5406894_-	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001295575.1\|5406921_5407542_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001285675.1\|5407538_5408420_-	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001700591.1\|5408557_5408602_+	trp operon leader peptide	NA	NA	NA	NA
WP_001194604.1\|5408693_5410256_+	anthranilate synthase component I	NA	NA	NA	NA
WP_000763520.1\|5410255_5411851_+	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	5.0e-52	38.2
WP_001302292.1\|5411854_5413213_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	4.3e-36	40.7
WP_000209521.1\|5413224_5414418_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_000443092.1\|5414417_5415224_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000807651.1\|5415604_5415784_+	general stress protein	NA	NA	NA	NA
WP_001056491.1\|5415869_5416370_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001079499.1\|5416415_5416922_+	ferritin-like domain-containing protein	NA	NA	NA	NA
5417073:5417100	attL	NA	NA	NA	NA
WP_000147167.1\|5417423_5417642_+	hypothetical protein	NA	NA	NA	NA
WP_001302903.1\|5418235_5418664_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.4e-22	42.1
WP_001144877.1\|5420392_5420983_-	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001303944.1\|5421166_5421814_+	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001414184.1\|5421950_5422097_-	hypothetical protein	NA	NA	NA	NA
WP_001303943.1\|5422524_5422803_+	hypothetical protein	NA	NA	NA	NA
WP_001171554.1\|5423142_5423523_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|5423519_5423867_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|5423916_5425455_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000938103.1\|5426420_5426990_-	T3SS effector caspase inhibitor NleF	NA	NA	NA	NA
WP_000950979.1\|5427055_5427967_-	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	3.0e-134	82.2
WP_106409364.1\|5428073_5428196_-	hypothetical protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_024262009.1\|5429337_5429526_-	hypothetical protein	NA	NA	NA	NA
WP_001025672.1\|5429793_5431119_+	type III secretion system effector NleA	H6WZN2	Escherichia_phage	1.9e-214	81.2
WP_001023474.1\|5432145_5432415_-\|tail	phage tail protein	A0A1U9AJC2	Stx1_converting_phage	3.2e-44	98.9
WP_000216532.1\|5432416_5433730_-\|tail	tail fiber protein	A0A0P0ZE15	Stx2-converting_phage	2.1e-80	97.9
WP_001228304.1\|5433881_5434481_-	outer membrane protein	Q9EV15	Enterobacteria_phage	1.6e-107	96.5
WP_115801855.1\|5434548_5436894_-	host specificity protein J	Q9EYE7	Enterobacteria_phage	0.0e+00	99.9
WP_001304109.1\|5436845_5438021_-	host specificity protein J	Q9EYE6	Enterobacteria_phage	1.2e-228	96.9
WP_151121042.1\|5438362_5438995_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	1.9e-95	90.9
WP_000194763.1\|5438940_5439684_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.4e-150	99.2
WP_001152159.1\|5439694_5440393_-\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	1.3e-129	97.4
WP_000807964.1\|5440392_5440734_-\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
WP_151121040.1\|5440726_5443969_-\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	97.3
WP_001453746.1\|5444016_5444226_-	DUF4035 domain-containing protein	A0A0P0ZED8	Stx2-converting_phage	2.6e-33	100.0
WP_000710952.1\|5444321_5444696_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_001275434.1\|5444710_5445427_-\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	1.6e-127	100.0
WP_000133388.1\|5445492_5445837_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573391.1\|5445833_5446280_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007901.1\|5446276_5446627_-\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000126019.1\|5446636_5446963_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_000267292.1\|5447042_5449544_-\|portal	phage portal protein	B6DZA1	Enterobacteria_phage	0.0e+00	99.2
WP_001063095.1\|5449489_5449711_-	hypothetical protein	B6DZA0	Enterobacteria_phage	2.9e-35	98.6
WP_000173030.1\|5449755_5451693_-\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	100.0
WP_038425863.1\|5451756_5453418_-\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.8
WP_000958416.1\|5453414_5453978_-\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	4.7e-90	100.0
WP_000279786.1\|5454267_5454633_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_000095736.1\|5454674_5454902_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_012816791.1\|5455326_5455512_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000539792.1\|5455739_5455886_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|5455885_5456455_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992137.1\|5456725_5457259_-	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_000731259.1\|5457309_5457654_-	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000284517.1\|5457658_5457874_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000143067.1\|5458023_5459877_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	97.9
WP_064761991.1\|5459996_5460182_-	hypothetical protein	Q5MBW5	Stx1-converting_phage	4.6e-26	94.6
WP_000935548.1\|5460673_5461732_-	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	1.1e-199	94.3
WP_000917750.1\|5461882_5462080_-	hypothetical protein	S5MQK8	Escherichia_phage	1.0e-28	98.5
WP_000640048.1\|5462321_5462852_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
WP_000904166.1\|5462860_5463220_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	3.6e-35	60.9
WP_001302148.1\|5463232_5464279_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	4.2e-108	54.2
WP_010917803.1\|5464280_5464559_-	hypothetical protein	I6PCV7	Cronobacter_phage	2.2e-11	48.4
WP_001217394.1\|5464628_5464886_-	hypothetical protein	NA	NA	NA	NA
WP_000961820.1\|5465106_5465319_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.4e-15	70.0
WP_001449026.1\|5465597_5466356_-	AcfC family adhesin Paa	NA	NA	NA	NA
WP_001505071.1\|5467054_5467219_-	hypothetical protein	NA	NA	NA	NA
WP_000774808.1\|5467215_5467797_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	8.6e-79	80.2
WP_001302276.1\|5467983_5468406_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.2e-77	98.6
WP_000020556.1\|5468437_5469478_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_000705621.1\|5469449_5470001_-	hypothetical protein	NA	NA	NA	NA
WP_000912298.1\|5469984_5470212_-	transcriptional regulator	NA	NA	NA	NA
WP_000787428.1\|5470288_5470696_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_001240336.1\|5470959_5471259_+	hypothetical protein	NA	NA	NA	NA
WP_001171903.1\|5471331_5471550_+	hypothetical protein	NA	NA	NA	NA
WP_000394552.1\|5471572_5471980_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
WP_000920491.1\|5471957_5472191_-	hypothetical protein	NA	NA	NA	NA
WP_122994727.1\|5472184_5472328_-	hypothetical protein	NA	NA	NA	NA
WP_000449192.1\|5472664_5472853_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001090200.1\|5472849_5473041_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048551.1\|5473133_5475605_+	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.2
WP_000113189.1\|5475669_5475918_+	excisionase	NA	NA	NA	NA
WP_000113674.1\|5475895_5477026_+\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
5477163:5477190	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP044142

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP044144

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP044143

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection