CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP044169	Campylobacter jejuni strain AR-0414 chromosome, complete genome	2 crisprs	cas9,cas1,cas2,c2c9_V-U4,cas14j,DEDDh	0	10	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP044169_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044169_1

180639-180724

Orphan

Consensus_repeat	Method
AAGGCTTTAAATGATTATGAAAGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP044169_1

>merge|NZ_CP044169|1|180639-180724|CRISPRCasFinder
AAGGCTTTAAATGATTATGAAAGCGGCAAAAGTTGGCAAGAAACAAAACAAGAACTACATAAGGCTTTAAATGATTATGAAAGCGG

>NZ_CP044169|1|1|180639-180724|CRISPRCasFinder
AAGGCTTTAAATGATTATGAAAGCGG	CAAAAGTTGGCAAGAAACAAAACAAGAACTACAT
AAGGCTTTAAATGATTATGAAAGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044169.1\|WP_002869700.1\|176344_177460_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_002869696.1\|173918_174146_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP044169.1\|WP_002860103.1\|183697_184351_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP044169.1\|WP_002787577.1\|188220_188760_-\|iron-transporter	unknown	unknown	gnl\|CDD\|226001
NZ_CP044169.1\|WP_002860109.1\|179726_180095_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_002870100.1\|182302_182740_+\|DUF411-domain-containing-protein	unknown	unknown	gnl\|CDD\|225564
NZ_CP044169.1\|WP_002869698.1\|175854_176037_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP044169.1\|WP_002782344.1\|180763_181051_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NZ_CP044169.1\|WP_002870101.1\|184347_185466_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957
NZ_CP044169.1\|WP_002860113.1\|174142_174511_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374224
NZ_CP044169.1\|WP_002860104.1\|183212_183701_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP044169.1\|WP_002870305.1\|179360_179588_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_079263628.1\|185455_186748_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP044169.1\|WP_002870103.1\|186734_188138_-\|DUF2318-domain-containing-protein	unknown	unknown	gnl\|CDD\|226828
NZ_CP044169.1\|WP_002869701.1\|177456_178650_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|316042
NZ_CP044169.1\|WP_002860108.1\|181586_182003_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_002870306.1\|178904_179111_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_002869699.1\|176047_176293_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_150969720.1\|182748_183252_-\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239264
NZ_CP044169.1\|WP_002782638.1\|174696_175551_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP044169.1\|WP_002869696.1\|173918_174146_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	2.34292e-07
NZ_CP044169.1\|WP_002860103.1\|183697_184351_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.87069e-106
NZ_CP044169.1\|WP_002870100.1\|182302_182740_+\|DUF411-domain-containing-protein	gnl\|CDD\|225564	COG3019, COG3019, Predicted metal-binding protein [General function prediction only].	2.42537e-70
NZ_CP044169.1\|WP_002869698.1\|175854_176037_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.63564e-07
NZ_CP044169.1\|WP_002782344.1\|180763_181051_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	0.00445178
NZ_CP044169.1\|WP_002860113.1\|174142_174511_+\|hypothetical-protein	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	9.52232e-09
NZ_CP044169.1\|WP_002860104.1\|183212_183701_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.39167e-15
NZ_CP044169.1\|WP_002787577.1\|188220_188760_-\|iron-transporter	gnl\|CDD\|226001	COG3470, Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism].	2.80272e-99
NZ_CP044169.1\|WP_079263628.1\|185455_186748_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	6.08319e-18
NZ_CP044169.1\|WP_002870103.1\|186734_188138_-\|DUF2318-domain-containing-protein	gnl\|CDD\|226828	COG4393, COG4393, Predicted membrane protein [Function unknown].	0
NZ_CP044169.1\|WP_002869701.1\|177456_178650_+\|AAA-family-ATPase	gnl\|CDD\|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	9.35358e-15
NZ_CP044169.1\|WP_002870101.1\|184347_185466_-\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	1.00883e-21
NZ_CP044169.1\|WP_150969720.1\|182748_183252_-\|redoxin-domain-containing-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.49713e-09

>NZ_CP044169.1|WP_002860109.1|179726_180095_+|hypothetical-protein
MEKVDYCRMSCLDGKINAFKYLLDLFLSDLENENDVKTCNMFENDTSIEYVKDMLMMMLDKIKEIVIDQDNCHHNIDMYASVYHEIIKDELGKEFTPKELKELHKKQEERLLKELLEGSKKK
>NZ_CP044169.1|WP_002870305.1|179360_179588_-|hypothetical-protein
MTRLEFDEKIKQLGLTRKIFADIAKVSYSGISTNWKDDKEIPSWVEPFLYYYEKGLALDELLKILEKYKNKEKLE
>NZ_CP044169.1|WP_002870306.1|178904_179111_-|hypothetical-protein
MTNNDFESILKKCNLSKKEFATLCDLPYPTLMNWVKADKTPNWVKSWLENYIKAQKYNKIKDLIKDDL
>NZ_CP044169.1|WP_002869701.1|177456_178650_+|AAA-family-ATPase
MKDYSKEINDLKKIKSQVIDKLDFKEFENIKSQINETSCNPSKIISQKNANIKNNSFVDLTQWAIRSVDLEKIEFTSLIDDFLDKGSISFLTSEANKGKTFLSFAICKHLLEFNKIRKIIYFDGDNSKITIKSRIKKSMQIGGYYFLDYPAFNYIQTSNALECGTDEIEVDFNFIVEKYLEPLMQSGGLVNVFIVFDSLFNFFNGDMNDNKKVAEFMKIIKKISHKGEATFLFIHHKGKSAENEFMGGVNFLNATDNLFKIQTSNNDGEILNIELNTKKARNFLPYNLKVDIDLNTLDLKIERAINENDTNFLTKAKEIIEQKGEILQGELLELLEKSKTDTHAIKKLESGKGLYFNIIEKSRATGGKALKYYVPLKENKTIINGIEINVEQTLFSE
>NZ_CP044169.1|WP_002869700.1|176344_177460_+|hypothetical-protein
MSISLFNDEIKAYIKNYYSIVDFLYLRYGLEFDKAGNERHNKSLKIKTNTCLITDFNGSFSGDIIDFIAFKENVELKEALIIFSDFNRLPTQKVGSFKPQKEPLKDNSYLKNIAYSLQANFNLANSDFIECKALEKAFFNDFRLFMHLCKLNFLKDDEFESILKDYFAFSKDDKSLAFILKDKNEIKSVAIREKLFKNELVKWFKVKGSSNKFIKLIKAKEKGLLKDYCFIFSGIKEIIVSELLGLNAVCFQSDSMMKNIHSHEQINELLNLIDNKRIVFIVENDESSFKANLELLKELIQINPLEKGYCVFNYDEVKNADFIDFLAYLMKELRQDYQRDKKGLNSFFSYMEKYFKNYFNKKMNLFLKVIK
>NZ_CP044169.1|WP_002869699.1|176047_176293_+|hypothetical-protein
MNNKQALEYLKSELCFIFNTRFRYFDFEIFNLLEKKIQILQKLPDFEREIKELLAILESNKKLFLKKNTFIKKEQKRQILL
>NZ_CP044169.1|WP_002869698.1|175854_176037_+|helix-turn-helix-domain-containing-protein
MQDTNKDFLTIQEVITLYSLSKDTQNKYRMQKKIPYIKIGKKIFYEKVKLDEWFKNHTIN
>NZ_CP044169.1|WP_002782638.1|174696_175551_+|hypothetical-protein
MLPSFKADFEVAIKWEKERECQEAINDKIEPYYNIEIEKAKDENYLYDYLCNSWLENPLYFIFQSEECTILNNKIEEQKIALCDFLLNNDILFNSFKIFNKLSPRERVKERENIIHNLSHFVKFSMEKFLYNTIFKSEIKKTSTQIKKDNEILVKALKILDENLKDENILKNTKIVQYHFYKFCNACRKIPAAEELKNYIFTNRLLSRNIKEYINFYIKLAINKNILFSIDFNNNKNYINACNNNFDDFMFKMQEKYKLNKREVKRKELKNAIIKAFDNYLRYN
>NZ_CP044169.1|WP_002860113.1|174142_174511_+|hypothetical-protein
MKKDINYYLNLPYKINLVKLDDGDYFAQFDDKELNKLVLMAGDGKTPNEAIEDLKNAFACYLEEALAKNEFIPEPIQKDKSKNLAITLKNSLVDEIDFYSKKMGLSRSAFLAVSAKAYIKTL
>NZ_CP044169.1|WP_002869696.1|173918_174146_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MNNKEKLIKELENNPKNASFANIEKLLSWYGYKLVSIRGSHHKFKKDNKSIIVPLHKPIKEFYVKQILKLLKDEK
>NZ_CP044169.1|WP_002782344.1|180763_181051_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MQILESDLFTNELNIILSFIVRKESIKVKNTFKNDLYKALKKLDFMPYKFRKSLAFDDENVRDFIFKGYVIPYKIDKEKDLIIILGIYKENLPNF
>NZ_CP044169.1|WP_002860108.1|181586_182003_+|hypothetical-protein
MKKLGLVLAALVALNVSAFADLIVINKKDLVPVSASEMQNKYFQESIKSTLTEPLFKKATFYEADIVAKVGPRTYNSTQAIIQKEYSDKSNYVYYKQVLILTSNGKRARLSTLSCEIASFDKKGYLCGGTADHNYSIK
>NZ_CP044169.1|WP_002870100.1|182302_182740_+|DUF411-domain-containing-protein
MKKTILTILFLLTLTQAKEIQVYESPTCGCCDLWADYMKAKGYGVSVHKTNDFLKIKEKMGIKDEYQSCHTGVIEGYAIEGHVPESAIVWLLENKPKDVIGISAPDMPQGSPGMEQGYSEKYPVILMKKDGSYELYGYFIGDKKL
>NZ_CP044169.1|WP_150969720.1|182748_183252_-|redoxin-domain-containing-protein
MGIFRIQAYFFALIIALFFVACDSGENFKALNSDKTYNFAYNGFEKSLKLNDKAQNFAFVFFAKDCGVCKEQIPILQNLAKNYDFNIFVVLGDANDANDAKAWADEKGLSNLAMFYEKRAAKYLSSAIGEIYGVPVLSFFKEGKMDEKFIGLTPYSILEKEIKKVKS
>NZ_CP044169.1|WP_002860104.1|183212_183701_-|TlpA-family-protein-disulfide-reductase
MKKSLLILSILFLLNACSFENSKDTGKVGEKSAEISAKDTLGKAVKLADDNTSLKVLVFFQNGCPSCLKELPSLDEFIQNHPNKISVYAINSIDNANVVKVLAEQFDFKNVKVLKDDLKITNDRYAVFATPTTIIIKDGMIKDRILGEKPWEFFESKLTSLL
>NZ_CP044169.1|WP_002860103.1|183697_184351_-|ABC-transporter-ATP-binding-protein
MMKKELIKINNLNKEFGKVKALNNINLSVYEGEWLAIMGPSGSGKSTLLNILSLMDTPSSGEYILDNENLEQMDEEQKITLRREKIGLVFQQFHLIPYLNALENVMLSQYYHSSVDEEDAKMVLEKVGLSHRLTHLPSQLSGGEQQRVCIARALINNPELLLADEPTGNLDEANEQIVLQTLQKLKNEGKTIVLITHNPDLAKFADRTLILQHGVLK
>NZ_CP044169.1|WP_002870101.1|184347_185466_-|FtsX-like-permease-family-protein
MVDKFFLNELFKSISFSYQRLFIIVLSVFIGALTCSAFLNIYFDIDIKLSKELKAYGANVMISPKQDENFISNIEYEKIKENLKARALTPFLYDFLNLGSTSGVVLGTDFRALKITKPFLEVKEGSFSLNDFDENSAFLGVNLAKQLGLKAGNELQIYNPSNGKNTKLTIKGILSSNDEFDSIVLAPLSVVQNLSDRAGINYANAVVYGNFDEVKVKTQAISNEFIDAKPISSVSLSEGLVLRKIKALMFLIILVVLIIVTTSVNTTLSSIIFSRKKEIALRLALGAKKSEIFKLFASECFIVSFFASLIGAFCGIFLANVFGYLIFNSSIDFRFIAVFIALIISLIFAFLAAFFPIKRALKINVCENLKGE
>NZ_CP044169.1|WP_079263628.1|185455_186748_-|ABC-transporter-permease
MMLAKMIFNSIFKNKIQKFLAFLTCFLATLLLSTMLNITLSIGDEVTKQLKSYGSNILVLPKGSSLSIEIGNELYEPLKNKNYLEEKNLYMIKDIYWRNNITALAPFLEGKITIENSQQKALIYGTYFQKAIKIKDDDDFITGIKSLYPYLAVQGEWAKDDSNEIMLGEDFAKNNKLKLGDTIKLIGENNQSKEAKIVGILLHANPKMSNKIIAPLNLAQDLLNKQGLYSSAEVRAFTIPESALSEKVRRMGEEKLDQLEYDKWYCSAYVGSIASQISDGLPGAGAKALNAISDAQSLVVKKIQSLMGITCIICLIVASIAISSLMSSEIHRRKKEIGLLKVLGANTFQIYLIFASENLIVALFAALFGFIFGTALSQIISLSIFGYFIDIAFIALPLSFIFAGLIALLGCLLPIKNITQLSAAGVLYGR
>NZ_CP044169.1|WP_002870103.1|186734_188138_-|DUF2318-domain-containing-protein
MSIYFMHFLISVLPLSILMAFITPNKKYIFKSFLVVFLGFLFGYFAFFIAAQFLKTENLIFNFDFVFIGLLLVSFIFYFWKKIEILNFILLGILSFCTALHYYFLSQDFPIFTSSLIDSEGISSLGFIALALLVCILIFFFLKWQKNFNQKTSFMLFLLLILIESDKALANILLTLMRNSIIETHAFLVSFVGKSNYFGVFGIYVYLIFITFLAFLSLKIRKKNISKKQILDINYRKNEAKTSLINRYFSSVFISCVISFCIVLYFFMVSSKPLTIDEPKEILPDKNGKFIFDIALLRDNKLHRFAYISAEGKVIRFFLINKREDKDSPVAVFDACMICGDMGYIKKDGQLICISCNVRIFLPSVGKSGGCNPIPLKYEYDGKKITIDVKDVIAGSNYFSQIKEIEVQDPVSKTKVINTQAPFSYSYKGITYYFSNQNNYEEFKKDPTKYVEENEAQFLIQRRNDVG
>NZ_CP044169.1|WP_002787577.1|188220_188760_-|iron-transporter
MIKKVLSVVAAAAVISTNLFAGEVPIGYPKELNGMEIAAVYLQPIEMEPRGIDLAASLADIHLEADIHALKNNPNGFPEGFWMPYLTIAYELKNTDTGAIKRGTLMPMVADDGPHYGANIAMEKDKKGGFGVGNYELTFYISNPEKQGFGRHVDEETGVGKWFEPFKVDYKFKYTGTPK

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Crispr_ID: NZ_CP044169_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044169_2

316231-316673

TypeII

Consensus_repeat	Method
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACT	PILER-CR
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	CRISPRCasFinder
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	CRT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAA	PILER-CR

6 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_CP044169_2

>merge|NZ_CP044169|2|316231-316673|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACTAAAGAAGACTGGAGTTTAAATGGGTGGATATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACTTTGCCTCATATTCTATATTATGAATTTCAATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACTTTTAGCAAGTGATAGTATTATAAACAATGATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACACTTAAAGCTTCATATCCAAATTTATATATATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACAGTGCTACAGCATTGCTAGAAGAGGTAATGGAGTAAGTGAAATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACTCCAAAGCGTTTTAAAGCATTTCCTAAAGCATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAT

>NZ_CP044169|2|1|316231-316465|PILER-CR
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACT	AAAGAAGACTGGAGTTTAAATGGGTGGAT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACT	TTGCCTCATATTCTATATTATGAATTTCA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACT	TTTAGCAAGTGATAGTATTATAAACAATG
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACACTTAAAGCTTCATATCCAAATTTATATATATTTTACCATAAAGAAATTTAAAAAGGGACTAAAA	CAGTGCTACAGCATTGCTAGAAGAGGTAATGGAGTAAGTGAA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAA	CTCCAAAGCGTTTTAAAGCATTTCCTAAAGC


>NZ_CP044169|2|2|316231-316673|CRISPRCasFinder
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TAAAGAAGACTGGAGTTTAAATGGGTGGAT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TTTGCCTCATATTCTATATTATGAATTTCA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TTTTAGCAAGTGATAGTATTATAAACAATG
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	ACTTAAAGCTTCATATCCAAATTTATATAT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	AGTGCTACAGCATTGCTAGAAGAGGTAATGGAGTAAGTGAA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TCCAAAGCGTTTTAAAGCATTTCCTAAAGC
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAT

>NZ_CP044169|2|1|316231-316673|CRT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TAAAGAAGACTGGAGTTTAAATGGGTGGAT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TTTGCCTCATATTCTATATTATGAATTTCA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TTTTAGCAAGTGATAGTATTATAAACAATG
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	ACTTAAAGCTTCATATCCAAATTTATATAT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	AGTGCTACAGCATTGCTAGAAGAGGTAATGGAGTAAGTGAA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAC	TCCAAAGCGTTTTAAAGCATTTCCTAAAGC
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAAT

>NZ_CP044169|2|2|316495-316672|PILER-CR
	AAAGAAGACTGGAGTTTAAATGGGTGGAT
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACT	TTGCCTCATATTCTATATTATGAATTTCA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACT	TTTAGCAAGTGATAGTATTATAAACAATG
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAACACTTAAAGCTTCATATCCAAATTTATATATATTTTACCATAAAGAAATTTAAAAAGGGACTAAAA	CAGTGCTACAGCATTGCTAGAAGAGGTAATGGAGTAAGTGAA
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAA	CTCCAAAGCGTTTTAAAGCATTTCCTAAAGC
ATTTTACCATAAAGAAATTTAAAAAGGGACTAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044169.1\|WP_002838167.1\|317986_318433_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP044169.1\|WP_020836909.1\|314771_315662_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP044169.1\|WP_002855343.1\|323243_325457_+\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239153
NZ_CP044169.1\|WP_002799306.1\|311820_314775_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP044169.1\|WP_002855427.1\|307644_308634_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP044169.1\|WP_150969730.1\|315654_316086_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP044169.1\|WP_002860686.1\|306978_307584_-\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NZ_CP044169.1\|WP_002874620.1\|316792_317983_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|223380
NZ_CP044169.1\|WP_002779488.1\|318433_318655_-\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|224888
NZ_CP044169.1\|WP_002867218.1\|306232_306982_-\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768
NZ_CP044169.1\|WP_052804184.1\|320321_321470_+\|carboxynorspermidine-decarboxylase	unknown	unknown	gnl\|CDD\|273414
NZ_CP044169.1\|WP_002886540.1\|310504_310726_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182621
NZ_CP044169.1\|WP_002803269.1\|322461_322653_+\|twin-arginine-translocation-signal-domain-containing-protein	unknown	unknown	gnl\|CDD\|236534
NZ_CP044169.1\|WP_032590681.1\|310718_311273_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225611
NZ_CP044169.1\|WP_002851502.1\|321773_322487_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225916
NZ_CP044169.1\|WP_079264536.1\|309203_310061_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044169.1\|WP_002851264.1\|325453_326095_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|319893
NZ_CP044169.1\|WP_002838169.1\|318656_320198_-\|multicopper-oxidase-CueO	unknown	unknown	gnl\|CDD\|225043
NZ_CP044169.1\|WP_002803271.1\|322652_323195_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239153
NZ_CP044169.1\|WP_002869217.1\|308630_308843_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP044169.1\|WP_002838167.1\|317986_318433_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.43458e-42
NZ_CP044169.1\|WP_020836909.1\|314771_315662_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.23079e-123
NZ_CP044169.1\|WP_002855343.1\|323243_325457_+\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	4.07231e-154
NZ_CP044169.1\|WP_002799306.1\|311820_314775_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP044169.1\|WP_002855427.1\|307644_308634_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP044169.1\|WP_002779488.1\|318433_318655_-\|MoaD/ThiS-family-protein	gnl\|CDD\|224888	COG1977, MoaD, Molybdopterin converting factor, small subunit [Coenzyme metabolism].	1.67964e-11
NZ_CP044169.1\|WP_002860686.1\|306978_307584_-\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	7.32317e-69
NZ_CP044169.1\|WP_002874620.1\|316792_317983_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|223380	COG0303, MoeA, Molybdopterin biosynthesis enzyme [Coenzyme metabolism].	2.10837e-142
NZ_CP044169.1\|WP_002851264.1\|325453_326095_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|319893	cd16371, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	6.18245e-57
NZ_CP044169.1\|WP_150969730.1\|315654_316086_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.43589e-58
NZ_CP044169.1\|WP_002867218.1\|306232_306982_-\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	1.07556e-92
NZ_CP044169.1\|WP_052804184.1\|320321_321470_+\|carboxynorspermidine-decarboxylase	gnl\|CDD\|273414	TIGR01047, carboxynorspermidine_decarboxylase, carboxynorspermidine decarboxylase. This protein is related to diaminopimelate decarboxylase. It is the last enzyme in norspermidine biosynthesis by an unusual pathway shown in Vibrio alginolyticus. [Central intermediary metabolism, Polyamine biosynthesis].	0
NZ_CP044169.1\|WP_002886540.1\|310504_310726_-\|hypothetical-protein	gnl\|CDD\|182621	PRK10654, dcuC, C4-dicarboxylate transporter DcuC; Provisional.	0.00639498
NZ_CP044169.1\|WP_002803269.1\|322461_322653_+\|twin-arginine-translocation-signal-domain-containing-protein	gnl\|CDD\|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	0.00537271
NZ_CP044169.1\|WP_032590681.1\|310718_311273_-\|hypothetical-protein	gnl\|CDD\|225611	COG3069, DcuC, C4-dicarboxylate transporter [Energy production and conversion].	6.37696e-13
NZ_CP044169.1\|WP_002851502.1\|321773_322487_+\|hypothetical-protein	gnl\|CDD\|225916	COG3381, TorD, Uncharacterized component of anaerobic dehydrogenases [General function prediction only].	0.00059716
NZ_CP044169.1\|WP_002838169.1\|318656_320198_-\|multicopper-oxidase-CueO	gnl\|CDD\|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	1.27659e-119
NZ_CP044169.1\|WP_002803271.1\|322652_323195_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	9.0213e-62

>NZ_CP044169.1|WP_150969730.1|315654_316086_+|CRISPR-associated-endonuclease-Cas2
MIEDKFMRVLLMFDVPAKSKKEQKLAGKFRNNLIKLGYFMLQFSVYMRICKGLSSAKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQINKKQEKYHQQNLFEF
>NZ_CP044169.1|WP_020836909.1|314771_315662_+|type-II-CRISPR-associated-endonuclease-Cas1
MSYDEAFKTLLISSNAKLNLELNHLVIKQDENIAKLFLKDINIIVLESLQVSISSALFNAFARHKIILLTCDETHSINGVFTPFLGHFQSAKIAKEQMNVSAQKKAILWQKIIKNKILNQAFILKKYNKIEQSNELINLAKKVSLNDSKNIEAVAAALYFKTLFGTSFSRDELCFENSALNYGYAIMRACIIRAVCISGLLPWLGIKHDNIYNSFALCDDLIEVFRASVDDCVLKLKGESEFLSKDDKRALIGNLQSKINFDGQNYPLNRAINHYVANFKNALLYEDELKIVKFDD
>NZ_CP044169.1|WP_002799306.1|311820_314775_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MARILAFDIGISSIGWAFSENDELKDCGVRIFTKAENPKTGESLALPRRLARSARKRLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRALNELLSKQDFARVILHIAKRRGYDDIKNSDDKEKGAILKAIKQNEEKLANYQSVGEYLYKEYFQKFKENSKEFTNVRNKKESYERCIAQSFLKDELKLIFKKQREFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPLAFMFVALTRIINLLNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKKLLGLSDDYEFKGEKGTYFIEFKKYKEFIKALGDHSLSQDDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLITPLMLEGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKVLNALLKKYGKVHKINIELAREVGKNYSQRAKIEKEQNENYKAKKDAELECEKLGLKINSKNILKLRLFKEQKEFCAYSGEKIKISDLQDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNQTPFEAFGNDSAKWQKIEVLAKNLPTKKQKRILDKNYKDKEQKDFKDRNLNDTRYIARLVLNYTKDYLDFLPLSDDENTKLNDTQKGSKVHVEAKSGMLTSALRHTWGFSAKDRNNHLHHAIDAVIIAYANNSIVKAFSDFKKEQESNSAELYAKKISELDYKNKRKFFEPFSGFRQKVLDKIDEIFVSKPERKKPSGALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSLYKDSLILIQTKDMQEPEFVYYNAFTSSTVSLIVSKHDNKFETLSKNQKILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK
>NZ_CP044169.1|WP_032590681.1|310718_311273_-|hypothetical-protein
MALKIVISSYAELLLLLLACMYPVLISLKIRPITTVCALSLIALDYDPKDGNSINMADMVGQSDNVVGLFLNYQIYSVITYVVIIAILIPFYFAWIDKRDKEKGVLNDEVEIPQIIDPKCPTFYTLFPWLPVIFLFIAYFFTIKLDVVIANFVRISLVFLVEFARHRNARKLGEDMMVILKGYG
>NZ_CP044169.1|WP_002886540.1|310504_310726_-|hypothetical-protein
MAEIFISVVSIIIAAGVCAKGIKALGGVNILTNAVSNLGTGNFAWFGILLSIAILSFLVYFANAILNRICIKI
>NZ_CP044169.1|WP_079264536.1|309203_310061_+|hypothetical-protein
MALIFPFLKAFYYEIARTTKQKYFTYAFNTFYLGLLTLIIGIGLVFLLASLVFWILAWVKFKEFDEQELSNLEERLAKAQKKVFDFDLKWIKITMASFIILNLLVLTFSFILEVISFEDFRFYYTKKTLFYTAIILALLSVFLFCKKIKNYKLFIYFFIWQGLSVFGSHLLFIPDFMVDQQIVYGSLNIILSLCYIIFAFLFFKILIQITKEKLFYLIFAFYVCIEILIILIFFIFMMVDNYYIFTKSPIKMLIDNYKLLFQVVYFVSFLIVWLMLKGQKNVKIC
>NZ_CP044169.1|WP_002869217.1|308630_308843_+|hypothetical-protein
MKTNYYDYLCAKMYVILPIKAHKDKLKFYLSYVNKKDKIFRVNVWKWAVLIKIAKDDKTKYFCSNVLNKG
>NZ_CP044169.1|WP_002855427.1|307644_308634_+|phosphoribosylformylglycinamidine-cyclo-ligase
MKISYEDAGVSIDNGNAFVEAIKPLVKETFNDNVVGGIGSFAGAFRMPSGFKKPVILGATDGVGTKLRLAIDAKKYDTIGQDLVAMCVNDLICNFATPLFFLDYYATAKLEVEVAKAVVSGIAKGCKMANCALIGGETAEMPGMYAKDDFDLAGFAVGMAEEDEIDRSKFVKNGDILLALPSSGLHSNGYSLARKVLFESLKLKFDDKIEGKNLIDILLEPTRIYVRDFLTLKPYISALAHITGGGLVENLPRVLPRGMGATIRKHHLKTPEIFYTIGQAVEESEMYRSFNMGVGLVMVVDPSNVSKVLENSDAFIIGEICINEGIVLE
>NZ_CP044169.1|WP_002860686.1|306978_307584_-|dephospho-CoA-kinase
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHKILDENALELEKIFSPFNLKNLLTKEKKIDRKILGEIVFNNKEAKKTLENFTHPKIRAKILEQMQILDKENKAFFVEIPLFFESGAYENLGKVIVIYTPKELSLKRIMQRDKLSLEAAKVRLDSQIDIEEKLKKADFIIKNTNSYVDFRQECVKVIQEISKGKM
>NZ_CP044169.1|WP_002867218.1|306232_306982_-|diaminopimelate-epimerase
MKFYKYCASGNDFVITNADRKEDRSALAKELCNRYEGIGGDGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFAHHINKINPNMSFLTGAGIIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCDTGVPHLVHFCQNLDEFDTILCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFTYKNEELFFEGKVKYCFEANYNFS
>NZ_CP044169.1|WP_002874620.1|316792_317983_-|molybdopterin-molybdotransferase-MoeA
MLMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFEDQDKPLKILGLTPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLVPVENIRIENDTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTRLNYSEIALLAELGFFHISVFIKPIVGVLSSGSEIKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILITTGGVSMGDFDFLKKAVKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYAREILSSWLLQPKDYICKAFLQGSYKKKTPYLEFVACNVEFKNGRILANLEGKKEGSSAIINNLNNKAALMVVPKECEILENESLVDIIFMP
>NZ_CP044169.1|WP_002838167.1|317986_318433_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKHFTLYQGSLDIPKIYSQWYEFAKDKNCGALLTFCGIVREEGGIEALSFDIYEPLLKKWFNEWQKRVDSDGISLLFAHSIGDVVVHESSYFAGILSKQRKLGLKLLNEFVEDFKASAPIWKYDVINKERIYAKERSTKLCGAGLLKG
>NZ_CP044169.1|WP_002779488.1|318433_318655_-|MoaD/ThiS-family-protein
MVKVEFLGPINKENLELEVKNLKELKEILQKDESLKEWLELCAVSLNDEIIFDENTKLKDGDKIALLPPVCGG
>NZ_CP044169.1|WP_002838169.1|318656_320198_-|multicopper-oxidase-CueO
MNRRNFLKFNALTLASMGVAYANPMHDMHSMHKNHSINHDLDTSFINFAPKNLKLLDPKQFPQGEILKALPLLKNESKEKNIFRATLEIKENHIELIKGKKTLFYTYNGLVPAPKIEVFEGDKLEILVKNKLKEATTIHWHGVPVPPDQDGSPHDPILAGEERIYRFKIPQDSAGTYWYHPHPHYTASKQVFMGLAGAFVIKAKKDALSHLKERDLMISDLRLDENAQIPNNNLNDWLNGREGEFVLINGQFKPQIKLATNERIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKTIYKEELFLSPASRVEVLIDAPKDGNFKLESAYYDRDKMMVKEEPNTLFLANISLKKENVELPKNLKIFKPSEEPKEFKEIIMSEDHMQMHGMMGKSESELKIALASMFLINGKSYDLKRIDLSSKLGVVEDWIVINKSHMDHPFHIHGTQFELISSKLNGKVQKAEFRALRDTINVRPNEELRLRMKQDFKGLRMYHCHILEHEDLGMMGNLEVKE
>NZ_CP044169.1|WP_052804184.1|320321_321470_+|carboxynorspermidine-decarboxylase
MFYEKIQTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLWEAKFAKEYMDKEIHTYSPAFKEDEIGEIASLSHHIVFNSLAQFHKFQAKTQKNSLGLRCNVEFSLAPKELYNPCGRYSRLGIRAKDFENVDLNAIEGLHFHALCEESADALEAVLKAFEEKFGKWIGQMKWVNFGGGHHITKKGYDVEKFIALCKNFSDKYGVQVYLEPGEAVGWQTGNLVASVVDIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNARILATRENEKISDLKESEFSYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGIRLPNLMLLDRKNELQMIREFSYKDYSLRN
>NZ_CP044169.1|WP_002851502.1|321773_322487_+|hypothetical-protein
MGALMDLEKLRLARSLYYQCLGELFVFSFSEERLSKLQEYLKTMQECLFDENLKSNFDILLKHLDDENSIQAFFKEYDLLFLSLKNSIPTTFSYIEEGFENSNPLLCVRQILVKSKIRRNEKFFKESEDSVGFCLLLMSEFLRQNEDDLAKELFEKVINKSIDEFLGDVFMNKNANLYKEIASIASAFMEFERLCFEVEKPAKINSKKVQNDLSRSEFLRREANKQRRTREKSQGIS
>NZ_CP044169.1|WP_002803269.1|322461_322653_+|twin-arginine-translocation-signal-domain-containing-protein
MKNRREFLKKSAFALGAAGVLGSTTLALAKDEERKDLVKGKSKKKEVLFQRSANWEKYYIKAE
>NZ_CP044169.1|WP_002803271.1|322652_323195_+|molybdopterin-dependent-oxidoreductase
MSSVGENIKLTRRSFLKMAALSSLATPLLARSETLREASADELKEAYEGSKKVKTVCTACSVGCGIIAEVQNGVWVRQEIAQDHPVSSGGHCCKGSDMIDMVRSHVRLKYPMKKENGEWKRISYEQALSEIGEKLAAYRKENPESVMFLGSAKLNNEQAYYIRKFAAFFGTNNVDHQARI
>NZ_CP044169.1|WP_002855343.1|323243_325457_+|formate-dehydrogenase-subunit-alpha
MTNHLGDIQRSKCIIIIGANPAVNHPVGFRHFLKAKEKGAKLIVVDPRFTKSAAKADIYARIRPGTDIAFMYGMLKIIFDEGLEDTKYLDERVFGIDKIREEAAKWTAEEVENVTGISKELLVQITHEVAKNKPTTLIWAMGLTQHTVGTSNTRLAPIVQMVLGNIGKFGGGVNILRGHDNVQGASDMACLSENLPGYYPLNEATWRYYAKIWGVDYEWLLGNFVSKDWMHKTGLSLARWWAAALNGKDGNDAIDNAGTPLKALVVMGNGITSTAQQVKVKEGLEALELLVLADPFVNEAGIIAERKDGIYLLPAATQFETSGSVTATNRSGQWRFKVVDPLYESMEDQEILFELAKKLGFYEDFTKTLRDEKGEIVWPENATREIAKAVRSIGLNGWSPERLKKHTLYWDKFDEVTLEGKDEVAGEYYGLPWPCWSDKHPGSPVLYNTDIEVAKGGMGFRNNFGLEYEGESLLAKNAPLNSPIDTGYPQITKDNIEKVLGITLSAQEKEKMGSTWSYDDSNIIATKCIEKGIVPYGNAKARAVVWTFKDKIPLHREPLHSPRNDLVQKYPSFEDQKALYRVDTKFVSVQQAKDYSKEFPLNLVTARLVNLNGAGMENRASMYLTRLTPEMFCEINPELAKEQDIKAGDMIWVHSPEGTKIHVRVKVNPGVAKDMIFLPFHFTGVMQGVDLTHNFPEGTKPYASGESANTVTNYGYDIMCQIPETKGGLCRISKDGK
>NZ_CP044169.1|WP_002851264.1|325453_326095_+|4Fe-4S-dicluster-domain-containing-protein
MSKVNFANLEKERLKFFCDNERCIDCNGCAVACDEAHELPIHIRRRRVITLNEGIQGKEVSTSISCMHCDDAPCSIVCPVDCFYIRADGIVLHDKEICIGCGYCLYACPFGAPQFPKDSVFGNKGIMDKCTMCAGGPEATNSEKERELYGQNRIAEGKVPVCAAMCSTKALLVGESSKIEEIYHNRLMNRNYGIPNPSESLEWKIAYTGKERL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP044169_2	2.2\|316334\|29\|NZ_CP044169\|PILER-CR	316334-316362	29	MN530981	Campylobacter phage DA10, complete genome	28731-28759	1	0.966
NZ_CP044169_2	2.5\|316333\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316333-316362	30	MN530981	Campylobacter phage DA10, complete genome	28730-28759	1	0.967
NZ_CP044169_2	2.9\|316608\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316608-316637	30	MN530981	Campylobacter phage DA10, complete genome	7439-7468	1	0.967
NZ_CP044169_2	2.11\|316607\|31\|NZ_CP044169\|PILER-CR	316607-316637	31	MN530981	Campylobacter phage DA10, complete genome	7438-7468	1	0.968
NZ_CP044169_2	2.3\|316400\|29\|NZ_CP044169\|PILER-CR	316400-316428	29	MN530981	Campylobacter phage DA10, complete genome	18503-18531	2	0.931
NZ_CP044169_2	2.6\|316399\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316399-316428	30	MN530981	Campylobacter phage DA10, complete genome	18503-18532	2	0.933
NZ_CP044169_2	2.7\|316465\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316465-316494	30	MN530981	Campylobacter phage DA10, complete genome	14249-14278	3	0.9
NZ_CP044169_2	2.2\|316334\|29\|NZ_CP044169\|PILER-CR	316334-316362	29	NC_018223	Enterococcus faecalis D32 plasmid EFD32pB, complete sequence	49546-49574	6	0.793
NZ_CP044169_2	2.2\|316334\|29\|NZ_CP044169\|PILER-CR	316334-316362	29	NZ_CP025123	Planococcus sp. MB-3u-03 plasmid unnamed12	100237-100265	6	0.793
NZ_CP044169_2	2.2\|316334\|29\|NZ_CP044169\|PILER-CR	316334-316362	29	NZ_KY303941	Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence	74202-74230	6	0.793
NZ_CP044169_2	2.3\|316400\|29\|NZ_CP044169\|PILER-CR	316400-316428	29	KJ019069	Synechococcus phage ACG-2014j isolate Syn7803US103, complete genome	65627-65655	6	0.793
NZ_CP044169_2	2.3\|316400\|29\|NZ_CP044169\|PILER-CR	316400-316428	29	NC_031900	Synechococcus phage S-CAM4 isolate 0809SB33, complete genome	65646-65674	6	0.793
NZ_CP044169_2	2.3\|316400\|29\|NZ_CP044169\|PILER-CR	316400-316428	29	KU686202	Synechococcus phage S-CAM4 isolate 1010NB23, complete genome	65704-65732	6	0.793
NZ_CP044169_2	2.3\|316400\|29\|NZ_CP044169\|PILER-CR	316400-316428	29	KU686200	Synechococcus phage S-CAM4 isolate 0309CC44, complete genome	65621-65649	6	0.793
NZ_CP044169_2	2.5\|316333\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316333-316362	30	NZ_KY303941	Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence	74201-74230	6	0.8
NZ_CP044169_2	2.5\|316333\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316333-316362	30	NC_018223	Enterococcus faecalis D32 plasmid EFD32pB, complete sequence	49546-49575	6	0.8
NZ_CP044169_2	2.6\|316399\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316399-316428	30	KJ019069	Synechococcus phage ACG-2014j isolate Syn7803US103, complete genome	65626-65655	6	0.8
NZ_CP044169_2	2.6\|316399\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316399-316428	30	NC_031900	Synechococcus phage S-CAM4 isolate 0809SB33, complete genome	65645-65674	6	0.8
NZ_CP044169_2	2.6\|316399\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316399-316428	30	KU686202	Synechococcus phage S-CAM4 isolate 1010NB23, complete genome	65703-65732	6	0.8
NZ_CP044169_2	2.6\|316399\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316399-316428	30	KU686200	Synechococcus phage S-CAM4 isolate 0309CC44, complete genome	65620-65649	6	0.8
NZ_CP044169_2	2.9\|316608\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316608-316637	30	NZ_CP015333	Borrelia hermsii HS1 isolate Browne Mountain plasmid lpV47, complete sequence	32985-33014	6	0.8
NZ_CP044169_2	2.2\|316334\|29\|NZ_CP044169\|PILER-CR	316334-316362	29	NC_019900	Lactobacillus plantarum strain BFE 5092 plasmid pMRI 5.2, complete sequence	210-238	7	0.759
NZ_CP044169_2	2.5\|316333\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316333-316362	30	NC_019900	Lactobacillus plantarum strain BFE 5092 plasmid pMRI 5.2, complete sequence	210-239	7	0.767
NZ_CP044169_2	2.5\|316333\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316333-316362	30	NZ_CP025123	Planococcus sp. MB-3u-03 plasmid unnamed12	100237-100266	7	0.767
NZ_CP044169_2	2.7\|316465\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316465-316494	30	NZ_LN890332	Leuconostoc gelidum subsp. gasicomitatum KG16-1 isolate LEKG1 plasmid II, complete sequence	5684-5713	7	0.767
NZ_CP044169_1	1.1\|180665\|34\|NZ_CP044169\|CRISPRCasFinder	180665-180698	34	NZ_CP017773	Paenibacillus crassostreae strain LPB0068 plasmid pPC03, complete sequence	32641-32674	8	0.765
NZ_CP044169_2	2.8\|316531\|41\|NZ_CP044169\|CRISPRCasFinder,CRT	316531-316571	41	NZ_CP048757	Campylobacter jejuni strain ZS006 plasmid pCJ41K-01, complete sequence	38631-38671	8	0.805
NZ_CP044169_2	2.9\|316608\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316608-316637	30	AP013387	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C42-MedDCM-OCT-S29-C52	5428-5457	8	0.733
NZ_CP044169_1	1.1\|180665\|34\|NZ_CP044169\|CRISPRCasFinder	180665-180698	34	MN694478	Marine virus AFVG_250M504, complete genome	19978-20011	9	0.735
NZ_CP044169_1	1.1\|180665\|34\|NZ_CP044169\|CRISPRCasFinder	180665-180698	34	MN694270	Marine virus AFVG_250M505, complete genome	20095-20128	9	0.735
NZ_CP044169_1	1.1\|180665\|34\|NZ_CP044169\|CRISPRCasFinder	180665-180698	34	MN694656	Marine virus AFVG_250M501, complete genome	19707-19740	9	0.735
NZ_CP044169_1	1.1\|180665\|34\|NZ_CP044169\|CRISPRCasFinder	180665-180698	34	MN693919	Marine virus AFVG_250M503, complete genome	16182-16215	9	0.735
NZ_CP044169_1	1.1\|180665\|34\|NZ_CP044169\|CRISPRCasFinder	180665-180698	34	MN694712	Marine virus AFVG_250M502, complete genome	16180-16213	9	0.735
NZ_CP044169_2	2.2\|316334\|29\|NZ_CP044169\|PILER-CR	316334-316362	29	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	554189-554217	9	0.69
NZ_CP044169_2	2.5\|316333\|30\|NZ_CP044169\|CRISPRCasFinder,CRT	316333-316362	30	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	554189-554218	9	0.7
NZ_CP044169_2	2.10\|316530\|42\|NZ_CP044169\|PILER-CR	316530-316571	42	NZ_CP048757	Campylobacter jejuni strain ZS006 plasmid pCJ41K-01, complete sequence	38630-38671	9	0.786

1. spacer 2.2|316334|29|NZ_CP044169|PILER-CR matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 1, identity: 0.966

ttgcctcatattctatattatgaatttca	CRISPR spacer
ttgcctgatattctatattatgaatttca	Protospacer
****** **********************

2. spacer 2.5|316333|30|NZ_CP044169|CRISPRCasFinder,CRT matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 1, identity: 0.967

tttgcctcatattctatattatgaatttca	CRISPR spacer
tttgcctgatattctatattatgaatttca	Protospacer
******* **********************

3. spacer 2.9|316608|30|NZ_CP044169|CRISPRCasFinder,CRT matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 1, identity: 0.967

tccaaagcgttttaaagcatttcctaaagc	CRISPR spacer
accaaagcgttttaaagcatttcctaaagc	Protospacer
 *****************************

4. spacer 2.11|316607|31|NZ_CP044169|PILER-CR matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 1, identity: 0.968

ctccaaagcgttttaaagcatttcctaaagc	CRISPR spacer
caccaaagcgttttaaagcatttcctaaagc	Protospacer
* *****************************

5. spacer 2.3|316400|29|NZ_CP044169|PILER-CR matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 2, identity: 0.931

tttagcaagtgatagtattataaacaatg	CRISPR spacer
tttagcaagcgatagtattataaataatg	Protospacer
*********.**************.****

6. spacer 2.6|316399|30|NZ_CP044169|CRISPRCasFinder,CRT matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 2, identity: 0.933

ttttagcaagtgatagtattataaacaatg	CRISPR spacer
ttttagcaagcgatagtattataaataatg	Protospacer
**********.**************.****

7. spacer 2.7|316465|30|NZ_CP044169|CRISPRCasFinder,CRT matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 3, identity: 0.9

acttaaagcttcatatccaaatttatatat	CRISPR spacer
gcttaaagcttcataaccaaatttataaat	Protospacer
.************** *********** **

8. spacer 2.2|316334|29|NZ_CP044169|PILER-CR matches to NC_018223 (Enterococcus faecalis D32 plasmid EFD32pB, complete sequence) position: , mismatch: 6, identity: 0.793

ttgcctcatattctatattatgaatttca	CRISPR spacer
ctacctcattttctgtattatgaattgct	Protospacer
.*.****** ****.*********** *

9. spacer 2.2|316334|29|NZ_CP044169|PILER-CR matches to NZ_CP025123 (Planococcus sp. MB-3u-03 plasmid unnamed12) position: , mismatch: 6, identity: 0.793

ttgcctcatattctatattatgaatttca	CRISPR spacer
tatcttcatattctatcttattaatttct	Protospacer
*  *.*********** **** ******

10. spacer 2.2|316334|29|NZ_CP044169|PILER-CR matches to NZ_KY303941 (Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence) position: , mismatch: 6, identity: 0.793

ttgcctcatattctatattatgaatttca	CRISPR spacer
ctacctcattttctgtattatgaattgct	Protospacer
.*.****** ****.*********** *

11. spacer 2.3|316400|29|NZ_CP044169|PILER-CR matches to KJ019069 (Synechococcus phage ACG-2014j isolate Syn7803US103, complete genome) position: , mismatch: 6, identity: 0.793

tttagcaagtgatagtattataaacaatg	CRISPR spacer
tccacaaagtgttagaattataaacaatg	Protospacer
*..*  ***** *** *************

12. spacer 2.3|316400|29|NZ_CP044169|PILER-CR matches to NC_031900 (Synechococcus phage S-CAM4 isolate 0809SB33, complete genome) position: , mismatch: 6, identity: 0.793

tttagcaagtgatagtattataaacaatg	CRISPR spacer
tccacaaagtgttagaattataaacaatg	Protospacer
*..*  ***** *** *************

13. spacer 2.3|316400|29|NZ_CP044169|PILER-CR matches to KU686202 (Synechococcus phage S-CAM4 isolate 1010NB23, complete genome) position: , mismatch: 6, identity: 0.793

tttagcaagtgatagtattataaacaatg	CRISPR spacer
tccacaaagtgttagaattataaacaatg	Protospacer
*..*  ***** *** *************

14. spacer 2.3|316400|29|NZ_CP044169|PILER-CR matches to KU686200 (Synechococcus phage S-CAM4 isolate 0309CC44, complete genome) position: , mismatch: 6, identity: 0.793

tttagcaagtgatagtattataaacaatg	CRISPR spacer
tccacaaagtgttagaattataaacaatg	Protospacer
*..*  ***** *** *************

15. spacer 2.5|316333|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NZ_KY303941 (Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence) position: , mismatch: 6, identity: 0.8

tttgcctcatattctatattatgaatttca	CRISPR spacer
tctacctcattttctgtattatgaattgct	Protospacer
*.*.****** ****.*********** *

16. spacer 2.5|316333|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NC_018223 (Enterococcus faecalis D32 plasmid EFD32pB, complete sequence) position: , mismatch: 6, identity: 0.8

tttgcctcatattctatattatgaatttca	CRISPR spacer
tctacctcattttctgtattatgaattgct	Protospacer
*.*.****** ****.*********** *

17. spacer 2.6|316399|30|NZ_CP044169|CRISPRCasFinder,CRT matches to KJ019069 (Synechococcus phage ACG-2014j isolate Syn7803US103, complete genome) position: , mismatch: 6, identity: 0.8

ttttagcaagtgatagtattataaacaatg	CRISPR spacer
ttccacaaagtgttagaattataaacaatg	Protospacer
**..*  ***** *** *************

18. spacer 2.6|316399|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NC_031900 (Synechococcus phage S-CAM4 isolate 0809SB33, complete genome) position: , mismatch: 6, identity: 0.8

ttttagcaagtgatagtattataaacaatg	CRISPR spacer
ttccacaaagtgttagaattataaacaatg	Protospacer
**..*  ***** *** *************

19. spacer 2.6|316399|30|NZ_CP044169|CRISPRCasFinder,CRT matches to KU686202 (Synechococcus phage S-CAM4 isolate 1010NB23, complete genome) position: , mismatch: 6, identity: 0.8

ttttagcaagtgatagtattataaacaatg	CRISPR spacer
ttccacaaagtgttagaattataaacaatg	Protospacer
**..*  ***** *** *************

20. spacer 2.6|316399|30|NZ_CP044169|CRISPRCasFinder,CRT matches to KU686200 (Synechococcus phage S-CAM4 isolate 0309CC44, complete genome) position: , mismatch: 6, identity: 0.8

ttttagcaagtgatagtattataaacaatg	CRISPR spacer
ttccacaaagtgttagaattataaacaatg	Protospacer
**..*  ***** *** *************

21. spacer 2.9|316608|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NZ_CP015333 (Borrelia hermsii HS1 isolate Browne Mountain plasmid lpV47, complete sequence) position: , mismatch: 6, identity: 0.8

tccaaagcgttttaaagcatttcctaaagc	CRISPR spacer
ttaaagacattttagagcatttcctaaagc	Protospacer
*. **..*.*****.***************

22. spacer 2.2|316334|29|NZ_CP044169|PILER-CR matches to NC_019900 (Lactobacillus plantarum strain BFE 5092 plasmid pMRI 5.2, complete sequence) position: , mismatch: 7, identity: 0.759

ttgcctcatattctatattatgaatttca	CRISPR spacer
aaacctcatattctaaattataaatttat	Protospacer
  .************ *****.*****

23. spacer 2.5|316333|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NC_019900 (Lactobacillus plantarum strain BFE 5092 plasmid pMRI 5.2, complete sequence) position: , mismatch: 7, identity: 0.767

tttgcctcatattctatattatgaatttca	CRISPR spacer
taaacctcatattctaaattataaatttat	Protospacer
*  .************ *****.*****

24. spacer 2.5|316333|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NZ_CP025123 (Planococcus sp. MB-3u-03 plasmid unnamed12) position: , mismatch: 7, identity: 0.767

tttgcctcatattctatattatgaatttca	CRISPR spacer
ctatcttcatattctatcttattaatttct	Protospacer
.*  *.*********** **** ******

25. spacer 2.7|316465|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NZ_LN890332 (Leuconostoc gelidum subsp. gasicomitatum KG16-1 isolate LEKG1 plasmid II, complete sequence) position: , mismatch: 7, identity: 0.767

acttaaagcttcatatccaaatttatatat	CRISPR spacer
gaatgaagcttcatatccaactttatcttt	Protospacer
.  *.*************** ***** * *

26. spacer 1.1|180665|34|NZ_CP044169|CRISPRCasFinder matches to NZ_CP017773 (Paenibacillus crassostreae strain LPB0068 plasmid pPC03, complete sequence) position: , mismatch: 8, identity: 0.765

caaaagttg----gcaagaaacaaaacaagaactacat	CRISPR spacer
----aggtgcaatgcaacaaacacaacaagaactacaa	Protospacer
    ** **    **** ***** *************

27. spacer 2.8|316531|41|NZ_CP044169|CRISPRCasFinder,CRT matches to NZ_CP048757 (Campylobacter jejuni strain ZS006 plasmid pCJ41K-01, complete sequence) position: , mismatch: 8, identity: 0.805

agtgctacagcattgctagaagaggtaatggagtaagtgaa	CRISPR spacer
agggtatttgtattgctagaagaggtaatggcgtaagtgaa	Protospacer
** *.  . *.******************** *********

28. spacer 2.9|316608|30|NZ_CP044169|CRISPRCasFinder,CRT matches to AP013387 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C42-MedDCM-OCT-S29-C52) position: , mismatch: 8, identity: 0.733

tccaaagcgttttaaagcatttcctaaagc	CRISPR spacer
agtaactggttttaaagcagttcctaaagt	Protospacer
  .**   *********** *********.

29. spacer 1.1|180665|34|NZ_CP044169|CRISPRCasFinder matches to MN694478 (Marine virus AFVG_250M504, complete genome) position: , mismatch: 9, identity: 0.735

caaaagttggcaagaaacaaaacaagaactacat	CRISPR spacer
ttgaagtgggcaaaaaacaaaacaagaagaaaag	Protospacer
. .**** *****.**************  * *

30. spacer 1.1|180665|34|NZ_CP044169|CRISPRCasFinder matches to MN694270 (Marine virus AFVG_250M505, complete genome) position: , mismatch: 9, identity: 0.735

caaaagttggcaagaaacaaaacaagaactacat	CRISPR spacer
ttgaagtgggcaaaaaacaaaacaagaagaaaag	Protospacer
. .**** *****.**************  * *

31. spacer 1.1|180665|34|NZ_CP044169|CRISPRCasFinder matches to MN694656 (Marine virus AFVG_250M501, complete genome) position: , mismatch: 9, identity: 0.735

caaaagttggcaagaaacaaaacaagaactacat	CRISPR spacer
ttgaagtgggcaaaaaacaaaacaagaagaaaag	Protospacer
. .**** *****.**************  * *

32. spacer 1.1|180665|34|NZ_CP044169|CRISPRCasFinder matches to MN693919 (Marine virus AFVG_250M503, complete genome) position: , mismatch: 9, identity: 0.735

caaaagttggcaagaaacaaaacaagaactacat	CRISPR spacer
ttgaagtgggcaaaaaacaaaacaagaagaaaag	Protospacer
. .**** *****.**************  * *

33. spacer 1.1|180665|34|NZ_CP044169|CRISPRCasFinder matches to MN694712 (Marine virus AFVG_250M502, complete genome) position: , mismatch: 9, identity: 0.735

caaaagttggcaagaaacaaaacaagaactacat	CRISPR spacer
ttgaagtgggcaaaaaacaaaacaagaagaaaag	Protospacer
. .**** *****.**************  * *

34. spacer 2.2|316334|29|NZ_CP044169|PILER-CR matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 9, identity: 0.69

ttgcctcatattctatattatgaatttca	CRISPR spacer
gatatccattttctatattatgaatttgg	Protospacer
    ..*** ***************** .

35. spacer 2.5|316333|30|NZ_CP044169|CRISPRCasFinder,CRT matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 9, identity: 0.7

tttgcctcatattctatattatgaatttca	CRISPR spacer
tgatatccattttctatattatgaatttgg	Protospacer
*    ..*** ***************** .

36. spacer 2.10|316530|42|NZ_CP044169|PILER-CR matches to NZ_CP048757 (Campylobacter jejuni strain ZS006 plasmid pCJ41K-01, complete sequence) position: , mismatch: 9, identity: 0.786

cagtgctacagcattgctagaagaggtaatggagtaagtgaa	CRISPR spacer
gagggtatttgtattgctagaagaggtaatggcgtaagtgaa	Protospacer
 ** *.  . *.******************** *********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

406279 : 413447

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002871486.1\|406279_406825_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D7XFA9	Escherichia_phage	2.2e-15	30.4
WP_002876273.1\|406824_407865_+	NAD-dependent epimerase/dehydratase family protein	M1HKX0	Paramecium_bursaria_Chlorella_virus	4.4e-65	40.5
WP_002876274.1\|407873_408908_+	GDP-mannose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	2.3e-143	72.8
WP_002860369.1\|408931_409870_+	NAD-dependent epimerase/dehydratase	A0A0F7LC08	uncultured_marine_virus	1.4e-73	45.9
WP_002876275.1\|409944_410964_+	D-glycero-D-manno-heptose 7-phosphate kinase	A0A222YW25	Synechococcus_phage	4.6e-59	41.0
WP_100221730.1\|411166_412174_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002876464.1\|412179_412785_+	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	4.9e-16	35.0
WP_002876465.1\|412772_413447_+	NTP transferase domain-containing protein	A0A2K9L821	Tupanvirus	4.2e-08	27.7

DBSCAN-SWA_2

831091 : 868050

Helicobacter_phage(100.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002782963.1\|831091_831730_+\|transposase	IS607-like element ISChh1 family transposase	A0A1S5RGS9	Helicobacter_phage	1.6e-97	86.8
WP_032588198.1\|831740_833009_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RFS3	Helicobacter_phage	1.2e-141	62.6
WP_002873071.1\|834608_835469_-	hypothetical protein	NA	NA	NA	NA
WP_052773720.1\|835641_836421_-	hypothetical protein	NA	NA	NA	NA
WP_150969771.1\|839612_840056_-	hypothetical protein	NA	NA	NA	NA
WP_002789080.1\|840055_840238_-	hypothetical protein	NA	NA	NA	NA
WP_002876473.1\|840237_840849_-	hypothetical protein	NA	NA	NA	NA
WP_052822995.1\|840850_842842_-	hypothetical protein	NA	NA	NA	NA
WP_150969773.1\|842841_845358_-	type VI secretion protein VgrG	NA	NA	NA	NA
WP_044260213.1\|845501_846134_-	hypothetical protein	NA	NA	NA	NA
WP_002791053.1\|846133_846484_-	DUF4299 family protein	NA	NA	NA	NA
WP_052775894.1\|846566_847133_-	hypothetical protein	NA	NA	NA	NA
WP_052775897.1\|847132_847840_-	hypothetical protein	NA	NA	NA	NA
WP_052775895.1\|847967_848522_-	hypothetical protein	NA	NA	NA	NA
WP_150969775.1\|849680_850238_-	hypothetical protein	NA	NA	NA	NA
WP_002779721.1\|850252_850639_-	hypothetical protein	NA	NA	NA	NA
WP_002779731.1\|851574_852825_-	hypothetical protein	NA	NA	NA	NA
WP_002779732.1\|852821_853286_-	hypothetical protein	NA	NA	NA	NA
WP_150969777.1\|853331_854276_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_150969779.1\|854286_855993_-	hypothetical protein	NA	NA	NA	NA
WP_150969781.1\|855985_856930_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_150969783.1\|856995_859644_-	type VI secretion protein VgrG	NA	NA	NA	NA
WP_002779653.1\|859795_860704_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002779654.1\|860700_862422_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002779655.1\|862418_862811_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002800582.1\|862813_864268_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002800584.1\|864269_864755_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002882777.1\|864823_866071_-	nucleobase:cation symporter	NA	NA	NA	NA
WP_002779659.1\|866196_866643_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002779660.1\|866652_868050_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_3

1640073 : 1648629

Streptococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001129922.1\|1640073_1640448_+	TnpV protein	D0R0F4	Streptococcus_phage	6.6e-64	96.8
WP_002808760.1\|1640814_1642734_+	tetracycline resistance ribosomal protection protein Tet(O)	A0A1B0RXH7	Streptococcus_phage	0.0e+00	98.1
WP_002779755.1\|1642785_1642959_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	4.6e-28	100.0
WP_032588198.1\|1643333_1644602_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RFS3	Helicobacter_phage	1.2e-141	62.6
WP_002782963.1\|1644612_1645251_-\|transposase	IS607-like element ISChh1 family transposase	A0A1S5RGS9	Helicobacter_phage	1.6e-97	86.8
WP_150969854.1\|1645838_1646186_+	hypothetical protein	NA	NA	NA	NA
WP_002915802.1\|1646320_1647448_+	hypothetical protein	NA	NA	NA	NA
WP_002915804.1\|1647447_1648629_+	AAA family ATPase	A0A127AWE7	Bacillus_phage	1.5e-48	33.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP044169

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection