CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP038153	Lactobacillus paracasei strain TCS chromosome, complete genome	1 crisprs	DinG,WYL,DEDDh,csa3,cas3,csn2,cas2,cas1,cas9	0	13	6	0
NZ_CP038154	Lactobacillus paracasei strain TCS plasmid unnamed, complete sequence	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP038153_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038153_1

2325417-2326838

TypeII

Consensus_repeat	Method
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CRISPRCasFinder
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CRT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	PILER-CR

21 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP038153_1

>merge|NZ_CP038153|1|2325417-2326838|CRISPRCasFinder,CRT,PILER-CR
GCTCTTGAACTGATTGATTCGACATCTACCTGAGACTAACTTCTCGATGGATGTGTTAGGATAATAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACAACAACTTGGGATTTGATTGTTAAAGTCATGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTCCATGGTAAAAACCTCCTATTATTTTGTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTGTTGCAATCGGTGAAAGTATCGCGATTGCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACACTTGATCATGCAGAAGGATATTGACGAGTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCGACAATCTCCCGACTGATGATATTGGCCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCGATGTGTTCTTGTCAAAACATTTTTTGCGGCTCTTGAACTGATTGATTCGACATCTACCTGAGACAACATATTGATCAGCCTTTCTTCAACGATCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCCATAAAGTTGCTAATTCTAGAAATATTTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTGTCAGCCATAAGCGTGTTAGCCGCTACGAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCGAGACCAACACCAGCGCAAGCGAACGCTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCGCGAGTTGATCGCAACGGAAGGCAGTTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCCAGTTGTTTAATGGATAAGCCTCTGATAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTTCGTCTTTAAGCGGTGCTAACCAATTTGGGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGGTTTCTTCGTTTACAATCGTGCCGCGATCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCGGTCAACTGTTGTGCGGTTTCATCAGTGCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACAGTGAGCCGGTGCATATTGCACCGGCTTTTGCTCTTGAACTGATTGATTCGACATCTACCTGAGACTGGTAATGGGTCGTCCGCATTATGATATTCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACCAGTAGATAAGATTGTTTTTGTCAAGTTTCGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGGGGTGATTTGTTGCATACCCACAATGTCAGCTCTTGAACTGATTGATTCGACATCTACCTGAGACGCCGTCTAAGCTGTTGTTCTGGAGAAAACAGCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

>NZ_CP038153|1|1|2325417-2326838|CRISPRCasFinder
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TAACTTCTCGATGGATGTGTTAGGATAATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACAACTTGGGATTTGATTGTTAAAGTCAT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TCCATGGTAAAAACCTCCTATTATTTTGTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTTGCAATCGGTGAAAGTATCGCGATTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	ACTTGATCATGCAGAAGGATATTGACGAGT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGACAATCTCCCGACTGATGATATTGGCC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGATGTGTTCTTGTCAAAACATTTTTTGCG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACATATTGATCAGCCTTTCTTCAACGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CCATAAAGTTGCTAATTCTAGAAATATTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTCAGCCATAAGCGTGTTAGCCGCTACGA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGAGACCAACACCAGCGCAAGCGAACGCTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGCGAGTTGATCGCAACGGAAGGCAGTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCAGTTGTTTAATGGATAAGCCTCTGATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TTCGTCTTTAAGCGGTGCTAACCAATTTGG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGTTTCTTCGTTTACAATCGTGCCGCGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGGTCAACTGTTGTGCGGTTTCATCAGTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AGTGAGCCGGTGCATATTGCACCGGCTTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGGTAATGGGTCGTCCGCATTATGATATTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CAGTAGATAAGATTGTTTTTGTCAAGTTTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGGGTGATTTGTTGCATACCCACAATGTCA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCGTCTAAGCTGTTGTTCTGGAGAAAACA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

>NZ_CP038153|1|1|2325417-2326838|CRT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TAACTTCTCGATGGATGTGTTAGGATAATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACAACTTGGGATTTGATTGTTAAAGTCAT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TCCATGGTAAAAACCTCCTATTATTTTGTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTTGCAATCGGTGAAAGTATCGCGATTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	ACTTGATCATGCAGAAGGATATTGACGAGT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGACAATCTCCCGACTGATGATATTGGCC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGATGTGTTCTTGTCAAAACATTTTTTGCG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AACATATTGATCAGCCTTTCTTCAACGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CCATAAAGTTGCTAATTCTAGAAATATTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTCAGCCATAAGCGTGTTAGCCGCTACGA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGAGACCAACACCAGCGCAAGCGAACGCTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGCGAGTTGATCGCAACGGAAGGCAGTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCAGTTGTTTAATGGATAAGCCTCTGATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TTCGTCTTTAAGCGGTGCTAACCAATTTGG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGTTTCTTCGTTTACAATCGTGCCGCGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGGTCAACTGTTGTGCGGTTTCATCAGTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AGTGAGCCGGTGCATATTGCACCGGCTTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGGTAATGGGTCGTCCGCATTATGATATTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CAGTAGATAAGATTGTTTTTGTCAAGTTTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGGGTGATTTGTTGCATACCCACAATGTCA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCGTCTAAGCTGTTGTTCTGGAGAAAACA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

>NZ_CP038153|1|1|2325945-2326838|PILER-CR
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CCATAAAGTTGCTAATTCTAGAAATATTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGTCAGCCATAAGCGTGTTAGCCGCTACGA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGAGACCAACACCAGCGCAAGCGAACGCTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCGCGAGTTGATCGCAACGGAAGGCAGTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCAGTTGTTTAATGGATAAGCCTCTGATA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TTCGTCTTTAAGCGGTGCTAACCAATTTGG
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGTTTCTTCGTTTACAATCGTGCCGCGATC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CGGTCAACTGTTGTGCGGTTTCATCAGTGC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	AGTGAGCCGGTGCATATTGCACCGGCTTTT
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	TGGTAATGGGTCGTCCGCATTATGATATTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	CAGTAGATAAGATTGTTTTTGTCAAGTTTC
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GGGGTGATTTGTTGCATACCCACAATGTCA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC	GCCGTCTAAGCTGTTGTTCTGGAGAAAACA
GCTCTTGAACTGATTGATTCGACATCTACCTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038153.1\|WP_003566944.1\|2335923_2336247_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038153.1\|WP_012491873.1\|2335361_2335730_+\|YxeA-family-protein	unknown	unknown	gnl\|CDD\|377665
NZ_CP038153.1\|WP_012491868.1\|2324433_2325276_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP038153.1\|WP_003605793.1\|2323327_2323753_-\|NusG-domain-II-containing-protein	unknown	unknown	gnl\|CDD\|227646
NZ_CP038153.1\|WP_012491864.1\|2314059_2314209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038153.1\|WP_003605783.1\|2314214_2314781_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP038153.1\|WP_012491866.1\|2316526_2318365_-\|PTS-beta-glucoside-transporter-subunit-EIIBCA	unknown	unknown	gnl\|CDD\|273919
NZ_CP038153.1\|WP_003605791.1\|2321439_2323131_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|227321
NZ_CP038153.1\|WP_012491865.1\|2314907_2316356_-\|family-1-glycosylhydrolase	unknown	unknown	gnl\|CDD\|236580
NZ_CP038153.1\|WP_002816285.1\|2324128_2324380_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP038153.1\|WP_003588557.1\|2336318_2338046_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP038153.1\|WP_012491867.1\|2318816_2319674_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|170086
NZ_CP038153.1\|WP_003580491.1\|2333170_2333965_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038153.1\|WP_003588545.1\|2327819_2328725_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP038153.1\|WP_014566806.1\|2333965_2335132_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038153.1\|WP_012491871.1\|2328922_2333008_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP038153.1\|WP_014566618.1\|2338026_2339769_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|227321
NZ_CP038153.1\|WP_003605790.1\|2319811_2321443_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP038153.1\|WP_003604680.1\|2326862_2327540_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP038153.1\|WP_003586314.1\|2327536_2327842_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043

Protein	Function_ID	Function_description	E-value
NZ_CP038153.1\|WP_012491873.1\|2335361_2335730_+\|YxeA-family-protein	gnl\|CDD\|377665	pfam06486, DUF1093, Protein of unknown function (DUF1093). This family consists of several hypothetical bacterial proteins of unknown function.	4.09197e-19
NZ_CP038153.1\|WP_012491868.1\|2324433_2325276_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.03773e-142
NZ_CP038153.1\|WP_003605793.1\|2323327_2323753_-\|NusG-domain-II-containing-protein	gnl\|CDD\|227646	COG5341, COG5341, Uncharacterized protein conserved in bacteria [Function unknown].	4.87983e-33
NZ_CP038153.1\|WP_003588545.1\|2327819_2328725_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.76359e-89
NZ_CP038153.1\|WP_003605783.1\|2314214_2314781_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.00337e-11
NZ_CP038153.1\|WP_012491866.1\|2316526_2318365_-\|PTS-beta-glucoside-transporter-subunit-EIIBCA	gnl\|CDD\|273919	TIGR01995, beta-glucosides_PTS_EIIBCA, PTS system, beta-glucoside-specific IIABC component. This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.	0
NZ_CP038153.1\|WP_003605791.1\|2321439_2323131_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	1.47636e-93
NZ_CP038153.1\|WP_012491865.1\|2314907_2316356_-\|family-1-glycosylhydrolase	gnl\|CDD\|236580	PRK09593, arb, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_CP038153.1\|WP_002816285.1\|2324128_2324380_+\|IS3-family-transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.47634e-08
NZ_CP038153.1\|WP_003588557.1\|2336318_2338046_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	7.03579e-159
NZ_CP038153.1\|WP_012491867.1\|2318816_2319674_-\|PRD-domain-containing-protein	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	3.39686e-35
NZ_CP038153.1\|WP_012491871.1\|2328922_2333008_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	5.52985e-120
NZ_CP038153.1\|WP_014566618.1\|2338026_2339769_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP038153.1\|WP_003605790.1\|2319811_2321443_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.53157e-92
NZ_CP038153.1\|WP_003604680.1\|2326862_2327540_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	8.55728e-83
NZ_CP038153.1\|WP_003586314.1\|2327536_2327842_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.69699e-23

>NZ_CP038153.1|WP_012491868.1|2324433_2325276_+|IS3-family-transposase
MCRILGVSRAQYYRYRSPKPSKRRAEDVDLKQRILRIFAEFKQRYGVMKIHHELNLELQPLQLRCSPRRISRLMKELDIHSVTVNKWKAASASKTKVEQRPNLLKQDFSTTGLNQKWTADMTYIQTKRHGWCYLSTIMDLHSRRIIGYSFSKKMDTDLVLKALESAVKNRTITGDLIIHTDLGSQYTSDDYNQRLTELHIRHSYSRKGCPYDNAPMESFHASLKKECVYPVPVFEDYETAAAVLFEYVHAFYNRKRIHSSLGYQTPLQVEIATLTSQMAA
>NZ_CP038153.1|WP_002816285.1|2324128_2324380_+|IS3-family-transposase
MPTRYDKEFKQNIINLYKQGESAAQLAREYGIGYSTVHKWIQGQAKTQSGKSPDEIKAMEKRLASLSEENEILKKALGFLAQK
>NZ_CP038153.1|WP_003605793.1|2323327_2323753_-|NusG-domain-II-containing-protein
MRWLKKYVRPFDYVIVIVLFVACFLPVGIFSLTEANVNTNQKVAVISIKGHVKRRIQLTTHTRHQQFTLYPAKGQYNIIEVQGARIRDKEDNSPDQIAVHTGWISQVGQQSICLPHKLLIEIKPAQAGTGTSGDTGGLVHP
>NZ_CP038153.1|WP_003605791.1|2321439_2323131_-|ATP-binding-cassette-domain-containing-protein
MLGLLKYGRDQRWAGVIETVFDWLPTLLPIMIALNFAAKRPGNALIITVILVLIWLGYVIGYERHHRHAWAMSAKRELRDHYFEALYQRNNAGDATAADNAVIQRDLGGLNNLDMFYSTLFPTLIQAGLTFLLLIGLSVWYGSWLAFLPLVCVFLIGFAMMFLGKKMSAQNKAHLAGFLRMGGRFMNDLSGMNTLVMYNAADRYAKKFADDSEYFRQATMNLLRTQLQVLFVINGFVYLTVFAGGFVTALQLAAGQLPAAGAFATWFALAMMMVNARQLGYFFHVVKSNGPALAGILATIAKSKTTPATVKITDNRPLKQLVLQDVAIGYEADAPLVSDINATLVPGKLYGLAGENGTGKSTLTQALLGQLTPLSGTIMADNTPVTALSNAQRAAVFGYVAANDYIFSGTIKENLLLGNQFGDQWQQHLDELGLMHFVTDLQDGYATEVGEGGRLLSPGQRQQLAFARMLLADKTVYLLDEMTSSIDAANAAIILAAIKRLSRQKIVLFISHDLSAMAEADVVWFIHDHQLISADHAQLYRDQPAYRHLVDNPEAMLKEGQPS
>NZ_CP038153.1|WP_003605790.1|2319811_2321443_-|ABC-transporter-ATP-binding-protein
MIRSLLRYTHHLTGTIIISFLIGLVAELTKVVVLVLAAMMLFDPQNASHLLIPGIIAVVIVGLGSFGEQYAGHFVAFHVLAELRGAVYRKLMQLAPAKLDSQGSGKLLKLIGSDIEAMEIFYAHTIVPVAIGLIYGVLMVAVYSSLNGPAAAVVLVSYAAVGLLIPYYRHEQMTAKAQAADRQKAVNQQYLLESVRGMAVLRQLEVADARMKTGNEGFDHEATAFQQSQFGQLLKNMSATLVMLLAWLFIVWLSGWTQPQPLQQALLAVFPLTFGPLLALTNLPASLLNGFAAARNLLNLLQEAPATSAAIDATQTLNQIAIIQVDHVTFKYPSRDETVLRQVSLSLHAGEIVGFVGASGSGKSTLAKLIMGWYPLTQGRILIDGIDVTKIDPASLRAQVNYLPQTPVFFSESVRDNLTLHDLTITDAQIWTVLDQVKLTSRLRQAEKGLDENVVSGQLQFSSGEQQRLELARALLHPSSVLVLDEPTSNLDTENERLILDTIKAYYHGIVIMISHRAESAAYADRLYRFADHRVSAASTEPK
>NZ_CP038153.1|WP_012491867.1|2318816_2319674_-|PRD-domain-containing-protein
MIIQNVLNNNAVVARHQQREVIVVERGIGFRAKKDAKMALRDSMKVYVPEDQAKLKIATATIASLPSAYLDLAAGIIQEAEKRLQTTFNSYLLIELADHVHFAVQRLHEKIVLHNKLLWEIQVAYTQEYEMGEWALHQIAAQLHEQLPEDEAGFIALKFVSNDLNHQQTVNSLAFTQTLASLTKIIFYNLGLDMNVKTPDYQRLVIHLKFFLQRMYAAAPSPLSLKMENYDYVLLKHLQQDYARAYHCMEDVDRFMQQKLAIAIPKNEQIYLTMHIARLAKSFAE
>NZ_CP038153.1|WP_012491866.1|2316526_2318365_-|PTS-beta-glucoside-transporter-subunit-EIIBCA
MNESGLAQQLLNLIGGKQNINQVWHCATRLRFTLKDRAKVPKDKIEALDGVITVVEASGQFQVVIGNNVGDVYHEVVKLEPSLSEGETSGETAAQGKMTFKSAFNSLLTFISGVFTPFLGAMAGAGILKGLLSLAVVMGWLTAKSGAYQIWWAAADGIFYFLPIALAFTAAKQLKVNQFVSMAIAAAMVSPGIVALGAKATTIDFFGIPVVPANYTATVLPILLVVVVQKFLEPVFNKLWHESVRNIMAPLCLLVVIVPLTLIVVGPISATVSSWLATAIVSLNKSVPILAGLVLGGFWQVIVIFGVHWALVPVMMNNIAQNGTDLMMPILLPAVLSQAGAALAVFLRTRDAKMKSLAGSSTITALFGITEPTIYGITLKLKKPFYLACVAGAVGGMIVAISGAGANAAALASVLSLPTFIGKGFGLSVVGDVVAFALGTVLTYFFGGINAGAKAKTAPSVNSEPGEALAAPVKGVLVPLTGLADEVFASETMGKGVAIVPENGIVKAPVAGVIRLLYPTGHAIGIQSDKGSEILIHIGIDAVNLKGKHFQPLVAQGQHVEIGTPLVQFDHEAIEKEGYESTVMMIVTNSDQYQIATLGQGATDDRPVMTLA
>NZ_CP038153.1|WP_012491865.1|2314907_2316356_-|family-1-glycosylhydrolase
MTYLNFPKNFLWGGATAANQLEGAYQEDGKGLSIADVLPQGKDRFTIVNRPDFNWTIDKSKYRYPNHQGIDHYHRFKEDIKLFSEMGFKCYRFSIAWSRIFPEGDEKTPNASGLKFYDEVIATCLKYDIEPVVTISHYEMPLHLVTKYGGWKNKRLIEFYKHFAETVLTRYFKQVKYWMTFNEINSAWAFPVMSQGLVANNGGNDKQTIFQAWHNQFVASAWAVKIGHALDPKLQVGCMLLYATTYGYDANPVNQLATLQQNQAFNFFCGDVQVRGEYPAYTDALMADNGFKFTDLDFSAEELTLLKNHPVDYIGFSYYMSAVVETVEKEHAEVGGNLLSGIKNPFLKASEWGWQIDPIGLRIALNQLYERYRKPLFIVENGLGAVDKPDADGKIKDDYRIDYLKQHIEQMGAAIHDGLDLMGYTPWGCIDLVSASSGQMSKRYGFIYVDLDDAGQGSLNRYKKQSFNWYQRVIASNGTDLG
>NZ_CP038153.1|WP_003605783.1|2314214_2314781_-|TetR/AcrR-family-transcriptional-regulator
MDTREKLVATAASLFQKEGVRATGLAQILTVSGTPKGSLYYYFPNGKAQLIEAAITYAGQHILEHVQQDLDRYKAPDAALAGQLESMATEMQEKGHLGGNSISLIALETGDDPELQAACSAVFTQLETLYIKKLTSAGIPPDRAQPLGQFIQASIEGAIILAATKNNPDLLRQTADQLTRLIKLALAA
>NZ_CP038153.1|WP_012491864.1|2314059_2314209_-|hypothetical-protein
MPVVCFYHLTRSPAQQPQCKDLGRNGQSATITPKATYTAVANRAGSRSL
>NZ_CP038153.1|WP_003604680.1|2326862_2327540_-|type-II-A-CRISPR-associated-protein-Csn2
MNLAYYPFQLITTKPSEVTVIDTASPKVLTDLIEALRNDLDKVVLSNDQLEPQEIRKASLWIGDPMLELDLDKLFQRLIYKRMELLIENQRLVELIDQSQQMAMYLLQDPFLSDLPVTVEPGGKLEQIMKYCNVHFDEAVTTESTSKIEALIQTLTKLEEKKLVILTNVSHYLSARDFSSVTEQIGDTELQVVLIEFSKVNRKKYFEKCQYIYIDEDFVDNRELD
>NZ_CP038153.1|WP_003586314.1|2327536_2327842_-|CRISPR-associated-endonuclease-Cas2
MRLMIMFDLPVLTSENRRNYRKFRKALINEGFLMMQYSIYVRVCSTKKSAEFLEHRIAAMKPPIGTVQTLMVTEAQYQAMHFLVGEAKQDIRNSADRTVII
>NZ_CP038153.1|WP_003588545.1|2327819_2328725_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRSLIVTQHCKVTTKNRTLVVQTDGEVNNVPIEDINQVVFTTTRALLSADAITTLAEANAKVIFSGRDGQPVTETTNLYSDRRKADLVRLQVNWPKSLVENLWTKIVAAKVSNQAQVTKLCGFDNQSLLDDLDTLEINDRSNREATAARKYFKLIFGDDFSRSDICATNAALNYGYSILLSTTNRAIVSAGHITEIGMHHSSVANQYNLGSDLMEPFRPAIDYWVANQKFTDLTPNIKYGLIALLNLEVTFNGKKALLQNALDEHVENCLAYLDGKRNNCRIEVEFPNEVSSDAFNDHV
>NZ_CP038153.1|WP_012491871.1|2328922_2333008_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTKLGKPYGIGVDIGSNSIGFAAVDENSHLIRLKGKTVIGARLFEEGKAAADRRASRTTRRRLSRNRWRLSFLRDFFESHITPTGPNFFMRQKYSEISPKDKARYKYEKRLFNDRTDAEFYQQYPTMYHLRNRLLTDPSKADVREIYFAIHHILKSRGHFLTSGYAKDFNTNKVALNEIFPALQDAYAQVYPDLDITFDENKVNEFKTVLLNEKATPSDTQRALVNLLLAEDGDKDILKQQKQVLTEFAKAVVGLKTKLNVALGTEVDSSEATVWNFSLGQLDDKWAGIESAMTDEGTEILDQIRDLYRARLLNGIVPAGKTLSQAKVDDYAQHHEDLELFKDYLKQLEDDGTAKAIRQLYDRYIDGDDAKPFVREDFVKALTKEVTAHPNAKSPELLERLAQPDFMLKQRNKANGAIPVQMQQRELDQIIKNQSVYYDWLAAPNPVEKHRKSMPYQLDELLNFRIPYYVGPLVTAKEQKAAQGGVFAWMVRKDPDGNITPYNFDEKVDREASANTFIQRMKTTDTYLIGEDVLPKQSLLYQRYEVLNELNNVRVNNEKLSIEQKQQVIRELFERHNSVTIKQFAENLRAHGDYAHIPEIRGLADEKRFLSSLSTYRQLKSLLPDAIDDPAKQADIENIIAWSTVFEDAAIFKTKLKEINWLDSQTITKLSNIRYRGWGQFSHKFLNGLTLGNGHTIIQELFLSNNNLMQILTDETLQKKMTELNADKLKAANINDAIDDAYTSPSNKKALRQVLRVIEDIKRAADGQDPSWLYVETADGGGTPGKRTRARQHQLQEIYANAAHELIDSAVRGELEDKIADKADFNDRLVLYFMQGGRDIYTGTPLNIDQLSSYDIDHILPQSLIKDNSLDNRVLVHAIINREKNATFASTIYAQKMNATWRQWHEAGLISGRKLRNLQMRPDQIDKYASGFVARQLVETRQIIKLTEQIVAAQYPETKIIAVKAGLSHQLREELEFPKNRDVNHYHHAFDAFLAARIGTYLLKRFPNLQAFFTYGKFKKADVKKLRGFNFIRDITHAEDKIVVKDTGEVIWDKKRDVDELDRIYNFKRMLITHEVHFEKADLFKQTVYGAKDSKEAGGKKQLISKKKGYPVDIYGGYTQETGSYLSVVRLTKKAMYAVVKVSTRDAAKLAVAKSISEQKENETLNDIIDEKLSKISKNGKITHELFEVVLPRVGQKTLFKNSKYNLFLVNSDTYMHNYQELWMPREYQKMWKDISLSKYGDAQTEDQLDQIFGFIVSQVNSYFNLYDINQFRKKLNDAADKFATLPMRDTDDMQGKIATIGQLLIGLQANAARSDLRNLDIKTPLGLLQIPNGISLDSDTSVVYQSPTGLLEREVHLSDL
>NZ_CP038153.1|WP_003580491.1|2333170_2333965_-|hypothetical-protein
MEATKLAKRKQWPVPFSQTEPHFTFNNWLKFFSVVLFTYLLFYTRNPIGGFFNMSGTTFLNVANGWTRAVVVFGGVLYCAIIFAGAVWAAGWDGLSQLFASFRWRDIWYVFAYGILYLIATTLGGILGDLVPIRFGVDFVNTLEAAQFGNLGAFSLISFRAFFMTLATQLTAVMIFLASQQLFSRLAIKHRRWALFLTYLLALAVTAVVTTTPLAPHVFVNIASGLVAQLPLYWVYRRSRNILVVTLSAFILMHVMIGLAVMLG
>NZ_CP038153.1|WP_014566806.1|2333965_2335132_-|hypothetical-protein
MSRQNLMILIVDLVLIIIFIGGFGWGIGTVKRYQVEPNTSRTETNTDSLYSESRFEKTLKKFKRLDLMVRLGPVKDAKTFNYTPDEFNVKYSSQPIVPGLKATKTLNAETGEVEVCTTMTPQGVTVAGDYLLTTAYDHDGFHNSVMYIQDLKTGKLLNTVVLNGRPHVGGLTYDAKNDNIWICGRRNNAAEVFAIKLKTALTYNVDKKAKAVAYSQRAQLGNISRASFVTYYENALFVGFFNPTGKGNIQRYPLNDKGQVVGKSLTSSISNQFDVLTQSVLHQDILSKIQGMAFCGDYTILSQSYGGGNSMLYIFKTDPKKTIFRASDAIDTFDMPSHLEQISTHDGRMYMMFESAAYAYRHRSTNQLDRVLSMNLEGFVQLVLKEEK
>NZ_CP038153.1|WP_012491873.1|2335361_2335730_+|YxeA-family-protein
MKKILIGIGIFIGLVILGGAGFYAWYTQSTPYYTQITTTGKKFDVIDDETGAPRDIDYAYTQMAYDEKGHGTEVDFNGHKSRPLKMQAYLRLDYSTRRNQVISWEAVPKEKVPKAALAKLNR
>NZ_CP038153.1|WP_003566944.1|2335923_2336247_+|hypothetical-protein
MTNEHKVLRGLSYISVIFAPILFPILVWIFTPQGSVTRDTAKHALWLHIIPTLLSIFIFMIIGGVGFFTNSINATSAVSLILLLVAMVVDIGMVVYNIYTGIKIITS
>NZ_CP038153.1|WP_003588557.1|2336318_2338046_-|thiol-reductant-ABC-exporter-subunit-CydC
MHWLKNEHWVRPDLKRYRGLLFWSLILGIMTFVFAGALMFTSGFLIDKSATKPLFAAIYVTVVLTRAFGIGRPVFQYIERLTSHNWVLRITSHMRRKLYKVLETDAAFVSEHHQTGDILGLLADDIGHIQNLYLRMIFPTVVGAGLTVIATLLLGWFNWGFALWIMLLLLFQVLILPWWGLVVERFRKAEQKQLNHDAYVSLTDSVLGLSDWVITHREKDFMSQSLAAPKKLAASTVKSKRFQWRRDFVGQLLFVLIVISMLIWTNLEWTGNQASANWVGAFVLVVFPLDQAFSGIAQGVGEWPTYRDAIRHLNDLQPVTRQLPQQQAVPTQFKEMTLQHLSFQYTPKDPELITDIDLTVHSGEKIAILGPSGMGKTTLLQLVLGDLTPTTGNVLIDGQDVLTYQQHRTNLFAVLDQSPFLFNTSIVNNVRLGNEQASDADVAAALKAVKLDQLVAQLPNGINSSVEEAGFGFSGGERQRLSLARILLQDAPIVLLDEPTVGLDPITEQALLETMFTVLQGKTILWVTHHLQGVNQTDRVIFLEDGRLTMNDTPSHLAKNDERYQNLYALDAGLR
>NZ_CP038153.1|WP_014566618.1|2338026_2339769_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKTLMRLSGMKRIMTMLAGFALVQAFVILLQGKFLAEGIVHSWNRQSLAGLWLPLGLFATAFVIRQLIVWVRNRIGARFAMTSSAWLQAQLLKHLYALGPAAVAKEGTCNLVTMALDGIPEAENYIELILNKILNMSIIPWVLVAYIWYENWLTGFTLLIMFPIIILFMVILGLAAQDKSESQYAGFQKMSNHFIDSLRGLKTLQLMGISRQYVNNVYDVSEDYRKQTMGVLRIAMLSTFALDFFTTLSIAVVAVFLGIKLMDGTIPLYPAMVALILAPEYFMPIRDFGTDYHATLNGKNAMKAIWQVIDQPLPTDTNVLPAFSRWRAQDTVTINHLDFTYPNERAGIQNANLQFTGTEKVAIIGASGSGKSTLLNLIGGFLQPQKAAMTVRGTKVPHMTQAAWQDHLSYIPQDPYLFADTITANIRFYRPDASDEDVKQAAEAAGLSHWIETLADGYATRIGEGGRGISGGQAQRIALARTLIDTNRSIWLFDEPTAHLDIETEAELKETLVPLFKNRLVIFATHRLHWLNQMDRVIVVDGGKIIAEGTPSELAAHSKPYQALVHEMRGEFNALVEK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP038153_1	1.21\|2326773\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326773-2326802	30	NZ_CP031181	Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_G, complete sequence	1301-1330	0	1.0
NZ_CP038153_1	1.21\|2326773\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326773-2326802	30	NZ_CP046668	Lactobacillus plantarum strain 83-18 plasmid p83-18.8, complete sequence	2173-2202	0	1.0
NZ_CP038153_1	1.21\|2326773\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326773-2326802	30	NC_019233	Lactobacillus rennini plasmid pREN, complete sequence	3859-3888	0	1.0
NZ_CP038153_1	1.20\|2326707\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326707-2326736	30	NZ_CP017904	Vibrio alginolyticus strain K05K4 plasmid pL289, complete sequence	152941-152970	5	0.833
NZ_CP038153_1	1.20\|2326707\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326707-2326736	30	NZ_CP017901	Vibrio alginolyticus strain K04M5 plasmid pL294, complete sequence	158597-158626	5	0.833
NZ_CP038153_1	1.20\|2326707\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326707-2326736	30	NZ_CP017909	Vibrio alginolyticus strain K06K5 plasmid pL291, complete sequence	155161-155190	5	0.833
NZ_CP038153_1	1.20\|2326707\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326707-2326736	30	NZ_CP017893	Vibrio alginolyticus strain K04M1 plasmid pL280, complete sequence	136535-136564	5	0.833
NZ_CP038153_1	1.20\|2326707\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326707-2326736	30	NZ_CP017898	Vibrio alginolyticus isolate K04M3 plasmid pL294, complete sequence	157962-157991	5	0.833
NZ_CP038153_1	1.3\|2325585\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325585-2325614	30	NZ_CP021954	Klebsiella pneumoniae strain AR_0148 plasmid tig00001025alt_u_pilon, complete sequence	7530-7559	6	0.8
NZ_CP038153_1	1.3\|2325585\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325585-2325614	30	KJ801817	Enterococcus phage ECP3, complete genome	49229-49258	6	0.8
NZ_CP038153_1	1.3\|2325585\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325585-2325614	30	AP018715	Enterococcus phage phiM1EF22 DNA, complete sequence	47479-47508	6	0.8
NZ_CP038153_1	1.3\|2325585\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325585-2325614	30	AP018714	Enterococcus phage phiEF17H DNA, complete sequence	49325-49354	6	0.8
NZ_CP038153_1	1.4\|2325651\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325651-2325680	30	MT074431	Salmonella phage demigod, complete genome	324-353	6	0.8
NZ_CP038153_1	1.4\|2325651\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325651-2325680	30	NC_023608	Salmonella phage vB_SenS-Ent2 complete genome	38327-38356	6	0.8
NZ_CP038153_1	1.5\|2325717\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325717-2325746	30	NZ_CP053710	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence	156078-156107	6	0.8
NZ_CP038153_1	1.5\|2325717\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325717-2325746	30	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	127368-127397	6	0.8
NZ_CP038153_1	1.8\|2325915\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325915-2325944	30	NZ_CP025942	Bacillus subtilis strain BJ3-2 plasmid unnamed, complete sequence	14925-14954	6	0.8
NZ_CP038153_1	1.8\|2325915\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325915-2325944	30	NZ_CP032854	Bacillus subtilis subsp. subtilis strain MH-1 plasmid unnamed1, complete sequence	22350-22379	6	0.8
NZ_CP038153_1	1.11\|2326113\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326113-2326142	30	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	37361-37390	6	0.8
NZ_CP038153_1	1.17\|2326509\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326509-2326538	30	NZ_CP020740	[Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence	44625-44654	6	0.8
NZ_CP038153_1	1.15\|2326377\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326377-2326406	30	NZ_CP025810	Sulfitobacter sp. SK025 plasmid unnamed2, complete sequence	57180-57209	7	0.767
NZ_CP038153_1	1.19\|2326641\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326641-2326670	30	NZ_CP042825	Rhizobium sp. WL3 plasmid unnamed2, complete sequence	467711-467740	7	0.767
NZ_CP038153_1	1.19\|2326641\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326641-2326670	30	NZ_CP015630	Borrelia turicatae strain BTE5EL plasmid lp159	26021-26050	7	0.767
NZ_CP038153_1	1.6\|2325783\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325783-2325812	30	NZ_CP030832	Neorhizobium sp. NCHU2750 plasmid pNCHU2750d, complete sequence	25343-25372	8	0.733
NZ_CP038153_1	1.9\|2325981\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2325981-2326010	30	AP014435	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22C-MedDCM-OCT-S41-C155, * SEQUENCING IN PROGRESS *, 2 ordered pieces	10947-10976	8	0.733
NZ_CP038153_1	1.9\|2325981\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2325981-2326010	30	AP013443	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22C-MedDCM-OCT-S23-C7	19838-19867	8	0.733
NZ_CP038153_1	1.9\|2325981\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2325981-2326010	30	AP014428	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S29-C101, * SEQUENCING IN PROGRESS *, 7 ordered pieces	8798-8827	8	0.733
NZ_CP038153_1	1.9\|2325981\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2325981-2326010	30	NZ_CP015354	Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence	45187-45216	8	0.733
NZ_CP038153_1	1.13\|2326245\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326245-2326274	30	NC_015062	Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence	582633-582662	8	0.733
NZ_CP038153_1	1.15\|2326377\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326377-2326406	30	NZ_CP046917	Paraburkholderia sp. DHF22 plasmid p1, complete sequence	140954-140983	8	0.733
NZ_CP038153_1	1.17\|2326509\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326509-2326538	30	MH576968	Streptomyces phage Wofford, complete genome	99312-99341	8	0.733
NZ_CP038153_1	1.17\|2326509\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326509-2326538	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	447964-447993	8	0.733
NZ_CP038153_1	1.19\|2326641\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326641-2326670	30	MT028491	Ochrobactrum phage vB_OspM_OC, complete genome	7390-7419	8	0.733
NZ_CP038153_1	1.19\|2326641\|30\|NZ_CP038153\|CRISPRCasFinder,CRT,PILER-CR	2326641-2326670	30	MK288021	Bacillus phage pW2, complete genome	66366-66395	8	0.733
NZ_CP038153_1	1.3\|2325585\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325585-2325614	30	LR135896	uncultured phage genomic DNA containing rbcL region region	22390-22419	9	0.7
NZ_CP038153_1	1.5\|2325717\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325717-2325746	30	NZ_CP049157	Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence	598353-598382	10	0.667
NZ_CP038153_1	1.5\|2325717\|30\|NZ_CP038153\|CRISPRCasFinder,CRT	2325717-2325746	30	NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	1044313-1044342	10	0.667

1. spacer 1.21|2326773|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031181 (Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_G, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtctaagctgttgttctggagaaaaca	CRISPR spacer
gccgtctaagctgttgttctggagaaaaca	Protospacer
******************************

2. spacer 1.21|2326773|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046668 (Lactobacillus plantarum strain 83-18 plasmid p83-18.8, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtctaagctgttgttctggagaaaaca	CRISPR spacer
gccgtctaagctgttgttctggagaaaaca	Protospacer
******************************

3. spacer 1.21|2326773|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NC_019233 (Lactobacillus rennini plasmid pREN, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtctaagctgttgttctggagaaaaca	CRISPR spacer
gccgtctaagctgttgttctggagaaaaca	Protospacer
******************************

4. spacer 1.20|2326707|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017904 (Vibrio alginolyticus strain K05K4 plasmid pL289, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

5. spacer 1.20|2326707|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017901 (Vibrio alginolyticus strain K04M5 plasmid pL294, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

6. spacer 1.20|2326707|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017909 (Vibrio alginolyticus strain K06K5 plasmid pL291, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

7. spacer 1.20|2326707|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017893 (Vibrio alginolyticus strain K04M1 plasmid pL280, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

8. spacer 1.20|2326707|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017898 (Vibrio alginolyticus isolate K04M3 plasmid pL294, complete sequence) position: , mismatch: 5, identity: 0.833

ggggtgatttgttgcatacccacaatgtca	CRISPR spacer
tggttgatttgtttcatacccacaatgata	Protospacer
 ** ********* ************* .*

9. spacer 1.3|2325585|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP021954 (Klebsiella pneumoniae strain AR_0148 plasmid tig00001025alt_u_pilon, complete sequence) position: , mismatch: 6, identity: 0.8

tccatggtaaaaacctcctattattttgtt	CRISPR spacer
tctaacataaaaatctccttttattttgtt	Protospacer
**.*  .******.***** **********

10. spacer 1.3|2325585|30|NZ_CP038153|CRISPRCasFinder,CRT matches to KJ801817 (Enterococcus phage ECP3, complete genome) position: , mismatch: 6, identity: 0.8

-tccatggtaaaaacctcctattattttgtt	CRISPR spacer
acccatta-aaaaacctcctactattttgta	Protospacer
 .**** . ************.********

11. spacer 1.3|2325585|30|NZ_CP038153|CRISPRCasFinder,CRT matches to AP018715 (Enterococcus phage phiM1EF22 DNA, complete sequence) position: , mismatch: 6, identity: 0.8

-tccatggtaaaaacctcctattattttgtt	CRISPR spacer
acccatta-aaaaacctcctactattttgta	Protospacer
 .**** . ************.********

12. spacer 1.3|2325585|30|NZ_CP038153|CRISPRCasFinder,CRT matches to AP018714 (Enterococcus phage phiEF17H DNA, complete sequence) position: , mismatch: 6, identity: 0.8

-tccatggtaaaaacctcctattattttgtt	CRISPR spacer
acccatta-aaaaacctcctactattttgta	Protospacer
 .**** . ************.********

13. spacer 1.4|2325651|30|NZ_CP038153|CRISPRCasFinder,CRT matches to MT074431 (Salmonella phage demigod, complete genome) position: , mismatch: 6, identity: 0.8

tgttgcaatcggtgaaagtatcgcgattgc	CRISPR spacer
tgttgcattcggtgaaagtgtcgctttttg	Protospacer
******* ***********.****  **

14. spacer 1.4|2325651|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NC_023608 (Salmonella phage vB_SenS-Ent2 complete genome) position: , mismatch: 6, identity: 0.8

tgttgcaatcggtgaaagtatcgcgattgc	CRISPR spacer
tgttgcattcggtgaaagtgtcgctttttg	Protospacer
******* ***********.****  **

15. spacer 1.5|2325717|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP053710 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
acgtcgtggtgcagaaggatatagacgagt	Protospacer
** * .* .************* *******

16. spacer 1.5|2325717|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
acgtcgtggtgcagaaggatgttgacgagt	Protospacer
** * .* .***********.*********

17. spacer 1.8|2325915|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP025942 (Bacillus subtilis strain BJ3-2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

aacatattgatcagcctttct--tcaacgatc	CRISPR spacer
accatattgatcagcatttcttctcaatgg--	Protospacer
* ************* *****  ****.*.

18. spacer 1.8|2325915|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP032854 (Bacillus subtilis subsp. subtilis strain MH-1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

aacatattgatcagcctttct--tcaacgatc	CRISPR spacer
accatattgatcagcatttcttctcaatgg--	Protospacer
* ************* *****  ****.*.

19. spacer 1.11|2326113|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 6, identity: 0.8

cgagaccaacaccagcgcaagcgaacgctt	CRISPR spacer
gaagaccaacaccagcgcaagcgcaagcaa	Protospacer
 .********************* * **

20. spacer 1.17|2326509|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020740 ([Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence) position: , mismatch: 6, identity: 0.8

agtgagccggtgcatattgcaccggctttt	CRISPR spacer
gatcggccggcgcatattgcgccggctttt	Protospacer
..* .*****.*********.*********

21. spacer 1.15|2326377|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025810 (Sulfitobacter sp. SK025 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

ggtttcttcgtttacaatcgtgccgcgatc	CRISPR spacer
tgcttcttcatttaccatcgtgccgcgcgg	Protospacer
 *.******.***** ***********

22. spacer 1.19|2326641|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042825 (Rhizobium sp. WL3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
tcgtaaatatgattgtttttgtcaagataa	Protospacer
. ***.*** **************** *

23. spacer 1.19|2326641|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015630 (Borrelia turicatae strain BTE5EL plasmid lp159) position: , mismatch: 7, identity: 0.767

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
ctgttgataagattgtttttgccaaatgat	Protospacer
* ** ****************.***.*  .

24. spacer 1.6|2325783|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP030832 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750d, complete sequence) position: , mismatch: 8, identity: 0.733

gcgacaatctcccgactgatgatattggcc	CRISPR spacer
ccgcggatctcccgaccgatgatattgaag	Protospacer
 **  .**********.**********.

25. spacer 1.9|2325981|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to AP014435 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22C-MedDCM-OCT-S41-C155, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
tggttggtttgctaattctaaaaatatttt	Protospacer
. .* .. ************.*********

26. spacer 1.9|2325981|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to AP013443 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22C-MedDCM-OCT-S23-C7) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
tggttggtttgctaattctaaaaatatttt	Protospacer
. .* .. ************.*********

27. spacer 1.9|2325981|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to AP014428 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S29-C101, *** SEQUENCING IN PROGRESS ***, 7 ordered pieces) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
tggttggtttgctaattctaaaaatatttt	Protospacer
. .* .. ************.*********

28. spacer 1.9|2325981|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015354 (Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence) position: , mismatch: 8, identity: 0.733

ccataaagttgctaattctagaaatatttt	CRISPR spacer
aaataaagttggtaatactagaaatgtgaa	Protospacer
  ********* **** ********.*

29. spacer 1.13|2326245|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NC_015062 (Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence) position: , mismatch: 8, identity: 0.733

gccagttgtttaatggataagcctctgata	CRISPR spacer
cccagttgtttaatggatacggcttattga	Protospacer
 ****************** * **.    *

30. spacer 1.15|2326377|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046917 (Paraburkholderia sp. DHF22 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

ggtttcttcgtttacaatcgtgccgcgatc	CRISPR spacer
cgagccgacgttgacaatcgtgccgcgatt	Protospacer
 *  .*  **** ****************.

31. spacer 1.17|2326509|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to MH576968 (Streptomyces phage Wofford, complete genome) position: , mismatch: 8, identity: 0.733

agtgagccggtgcatattgcaccggctttt	CRISPR spacer
gactggccggtgcttattgcaccggcctta	Protospacer
... .******** ************.**

32. spacer 1.17|2326509|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 8, identity: 0.733

agtgagccggtgcatattgcaccggctttt	CRISPR spacer
tattttccggggcatattgtaccggctttc	Protospacer
 .*   **** ********.*********.

33. spacer 1.19|2326641|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to MT028491 (Ochrobactrum phage vB_OspM_OC, complete genome) position: , mismatch: 8, identity: 0.733

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
agatggataagattgtcattgtcaagttct	Protospacer
 ..*.***********. **********..

34. spacer 1.19|2326641|30|NZ_CP038153|CRISPRCasFinder,CRT,PILER-CR matches to MK288021 (Bacillus phage pW2, complete genome) position: , mismatch: 8, identity: 0.733

cagtagataagattgtttttgtcaagtttc	CRISPR spacer
tcatctatactattgtttttgtcaagtttg	Protospacer
. .*  ***  ******************

35. spacer 1.3|2325585|30|NZ_CP038153|CRISPRCasFinder,CRT matches to LR135896 (uncultured phage genomic DNA containing rbcL region region) position: , mismatch: 9, identity: 0.7

tccatggtaaaaacctcctattattttgtt	CRISPR spacer
gatatggtaaaagccttctattatttccgc	Protospacer
  .*********.***.*********.  .

36. spacer 1.5|2325717|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP049157 (Caballeronia sp. SBC1 plasmid pSBC1_1, complete sequence) position: , mismatch: 10, identity: 0.667

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
gtcgcgccatgcagaatgatattgacgatg	Protospacer
...  ..********* ***********

37. spacer 1.5|2325717|30|NZ_CP038153|CRISPRCasFinder,CRT matches to NZ_CP049317 (Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence) position: , mismatch: 10, identity: 0.667

acttgatcatgcagaaggatattgacgagt	CRISPR spacer
gtcgcgccatgcagaatgatattgacgatg	Protospacer
...  ..********* ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

555604 : 638030

106

Lactobacillus_phage(64.52%)

integrase,transposase

attL 556125:556140|attR 587450:587465

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003577893.1\|555604_556534_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	5.9e-106	63.7
556125:556140	attL	NA	NA	NA	NA
WP_012491046.1\|556727_557273_-	hypothetical protein	NA	NA	NA	NA
WP_003569067.1\|557593_558763_-\|integrase	site-specific integrase	Q6J1W6	Lactobacillus_phage	6.6e-219	98.2
WP_003573997.1\|558875_559136_-	hypothetical protein	B4XYT0	Lactobacillus_phage	2.5e-09	40.7
WP_003589914.1\|559225_559846_+	hypothetical protein	NA	NA	NA	NA
WP_012491047.1\|559829_560066_-	hypothetical protein	NA	NA	NA	NA
WP_003661643.1\|560066_560174_-	hypothetical protein	NA	NA	NA	NA
WP_003589919.1\|560258_560966_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_003572182.1\|561124_561547_-	ImmA/IrrE family metallo-endopeptidase	A0A0P0IJN5	Lactobacillus_phage	7.8e-21	39.1
WP_003572184.1\|561539_561893_-	helix-turn-helix transcriptional regulator	A0A141E1M3	Streptococcus_phage	7.7e-14	40.9
WP_003574003.1\|562136_562385_+	hypothetical protein	A0A0P0ID24	Lactobacillus_phage	2.7e-37	97.5
WP_003572187.1\|562426_562627_+	hypothetical protein	NA	NA	NA	NA
WP_003572188.1\|562597_563431_-	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	2.8e-46	37.8
WP_010493122.1\|563491_564250_+	hypothetical protein	A0A1B0YEA7	Lactobacillus_phage	1.9e-41	49.4
WP_003572193.1\|564250_564430_+	hypothetical protein	NA	NA	NA	NA
WP_003572196.1\|564422_564674_-	DUF1883 domain-containing protein	NA	NA	NA	NA
WP_003572199.1\|564739_565096_+	DUF771 domain-containing protein	U5U4L9	Lactobacillus_phage	2.0e-62	98.3
WP_010493127.1\|565095_565188_+	hypothetical protein	A0A0P0IZE0	Lactobacillus_phage	4.5e-11	96.7
WP_003572201.1\|565180_565384_+	hypothetical protein	NA	NA	NA	NA
WP_003586921.1\|565366_565912_-	hypothetical protein	NA	NA	NA	NA
WP_010493132.1\|566092_566407_+	hypothetical protein	NA	NA	NA	NA
WP_003589923.1\|566399_567146_+	DnaD domain protein	A0A0N7IRA7	Lactobacillus_phage	5.8e-35	56.1
WP_012491048.1\|567160_567985_+	DNA replication protein	A0A0P0I3L9	Lactobacillus_phage	9.6e-116	74.7
WP_003574016.1\|567984_568503_+	exonuclease domain-containing protein	NA	NA	NA	NA
WP_003564822.1\|568549_568972_+	hypothetical protein	NA	NA	NA	NA
WP_003572217.1\|568973_569711_+	hypothetical protein	A0A097BY87	Enterococcus_phage	1.3e-47	43.0
WP_010493149.1\|569722_570010_+	hypothetical protein	Q8LTA8	Lactobacillus_phage	1.6e-38	76.8
WP_010493151.1\|570079_570412_+	hypothetical protein	NA	NA	NA	NA
WP_010493154.1\|570926_571370_+	autolysin regulatory protein arpU	A0A0P0IZI6	Lactobacillus_phage	1.2e-77	97.3
WP_032675380.1\|571714_571912_+	hypothetical protein	NA	NA	NA	NA
WP_003572221.1\|571883_572537_+	hypothetical protein	NA	NA	NA	NA
WP_080513722.1\|572606_572825_+	hypothetical protein	NA	NA	NA	NA
WP_012491050.1\|572787_573786_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-55	39.8
WP_003573729.1\|573981_574200_-	CsbD family protein	NA	NA	NA	NA
WP_010493173.1\|575732_576068_+	ribonucleoside-diphosphate reductase	A0A0N7IRA2	Lactobacillus_phage	6.8e-52	90.6
WP_010493174.1\|576064_576175_+	hypothetical protein	NA	NA	NA	NA
WP_076626284.1\|576187_576520_+\|transposase	transposase	NA	NA	NA	NA
WP_003582147.1\|576549_577278_+	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	7.6e-32	40.1
WP_014951815.1\|577211_578153_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	3.1e-17	28.2
WP_016364094.1\|578198_579062_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	3.1e-24	30.5
WP_003589963.1\|579376_579535_+	hypothetical protein	NA	NA	NA	NA
WP_014566421.1\|579623_580070_+	hypothetical protein	NA	NA	NA	NA
WP_003572355.1\|580081_580348_+	hypothetical protein	NA	NA	NA	NA
WP_003572358.1\|580366_580543_+	hypothetical protein	NA	NA	NA	NA
WP_003572360.1\|580544_580772_+	hypothetical protein	NA	NA	NA	NA
WP_010493190.1\|580814_582056_+	hypothetical protein	NA	NA	NA	NA
WP_010493192.1\|582033_583584_+	DUF5011 domain-containing protein	NA	NA	NA	NA
WP_012491056.1\|583593_584013_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_012491057.1\|584021_584600_+	hypothetical protein	NA	NA	NA	NA
WP_012491058.1\|584626_587086_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_012491059.1\|587082_589140_+	hypothetical protein	NA	NA	NA	NA
587450:587465	attR	NA	NA	NA	NA
WP_003582234.1\|589145_589481_+	hypothetical protein	NA	NA	NA	NA
WP_014566422.1\|589464_590061_+	hypothetical protein	NA	NA	NA	NA
WP_012491061.1\|590041_591970_+	type IV secretory pathway, VirB4 protein	NA	NA	NA	NA
WP_012491062.1\|591971_592982_+	hydrolase	A0A1X9SGZ2	Bradyrhizobium_phage	1.2e-14	37.9
WP_012491063.1\|592997_593642_+	hypothetical protein	NA	NA	NA	NA
WP_012491064.1\|593638_594046_+	thioredoxin family protein	NA	NA	NA	NA
WP_014566423.1\|594035_594857_+	hypothetical protein	NA	NA	NA	NA
WP_080513752.1\|595229_595430_-	hypothetical protein	NA	NA	NA	NA
WP_012491066.1\|595451_595652_+	hypothetical protein	NA	NA	NA	NA
WP_012491067.1\|595648_595906_+	hypothetical protein	NA	NA	NA	NA
WP_012491068.1\|595944_596379_+	hypothetical protein	NA	NA	NA	NA
WP_012491069.1\|596371_597616_+	hypothetical protein	NA	NA	NA	NA
WP_012491070.1\|597654_597903_+	hypothetical protein	NA	NA	NA	NA
WP_014566424.1\|597889_600436_+	DUF3991 domain-containing protein	NA	NA	NA	NA
WP_014566737.1\|600435_600645_+	hypothetical protein	NA	NA	NA	NA
WP_012491077.1\|602328_602775_-	hypothetical protein	NA	NA	NA	NA
WP_016379788.1\|602774_602981_+	hypothetical protein	NA	NA	NA	NA
WP_012491078.1\|603277_604159_+	hypothetical protein	NA	NA	NA	NA
WP_012491079.1\|604175_604535_+	transcriptional regulator	NA	NA	NA	NA
WP_012491080.1\|604613_605285_+	class A sortase	NA	NA	NA	NA
WP_012491081.1\|605419_605650_+	hypothetical protein	NA	NA	NA	NA
WP_041168760.1\|606070_607627_+	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_095691935.1\|608311_609099_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_012491083.1\|609466_609739_-	hypothetical protein	NA	NA	NA	NA
WP_012491084.1\|609798_612603_-	cation-transporting P-type ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	1.5e-72	27.6
WP_121497133.1\|612942_613062_+\|transposase	transposase	NA	NA	NA	NA
WP_012491085.1\|613144_613828_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	3.1e-59	51.3
WP_005688360.1\|614302_615457_+	cation:proton antiporter	NA	NA	NA	NA
WP_123796556.1\|615465_616253_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_101869790.1\|616217_616406_+	hypothetical protein	NA	NA	NA	NA
WP_012491088.1\|616402_617023_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.9e-56	52.9
WP_012491089.1\|617210_618140_-	mannose-6-phosphate isomerase	NA	NA	NA	NA
WP_012491090.1\|618153_618984_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_012491091.1\|618996_619851_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_012491092.1\|619879_620374_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_012491093.1\|620417_620837_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_012491094.1\|621013_621736_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_012491095.1\|621833_622571_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012491096.1\|622875_623196_+	hypothetical protein	NA	NA	NA	NA
WP_012491097.1\|623292_623880_+	recombinase family protein	M4QQC6	Vibrio_phage	1.0e-18	42.3
WP_012491098.1\|624014_625376_+	sodium:solute symporter	NA	NA	NA	NA
WP_003567312.1\|625576_626134_+	hypothetical protein	NA	NA	NA	NA
WP_123796556.1\|626655_627443_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_123031263.1\|627894_628638_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.5e-136	98.4
WP_012491102.1\|628910_629042_-\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	2.3e-16	90.7
WP_016380143.1\|629122_629305_+	hypothetical protein	NA	NA	NA	NA
WP_003593245.1\|629298_630216_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_003593246.1\|630362_630971_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.8e-50	52.8
WP_010010565.1\|630981_632250_+	NADPH-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.8e-49	47.7
WP_012491102.1\|632523_632655_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	2.3e-16	90.7
WP_123031263.1\|632927_633671_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.5e-136	98.4
WP_012491103.1\|633875_635555_+	D-lactate dehydrogenase	NA	NA	NA	NA
WP_012491105.1\|635901_636099_+	hypothetical protein	NA	NA	NA	NA
WP_003585300.1\|636073_636427_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_012491106.1\|636527_638030_+\|transposase	IS66 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

892806 : 960912

Lactobacillus_phage(94.23%)

capsid,tRNA,tail,integrase,holin,terminase,portal,transposase,head,protease

attL 919453:919469|attR 965977:965993

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011674296.1\|892806_894309_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_003564071.1\|894603_895152_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_014566463.1\|895531_897250_+	APC family permease	NA	NA	NA	NA
WP_003569394.1\|897536_898745_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_003564079.1\|898747_899776_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_003564081.1\|899788_900802_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_003564083.1\|900837_901191_+	hypothetical protein	NA	NA	NA	NA
WP_014566464.1\|901276_902452_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_003564087.1\|902697_902976_+	YkuJ family protein	NA	NA	NA	NA
WP_003564089.1\|902960_903101_-	hypothetical protein	NA	NA	NA	NA
WP_012491223.1\|903206_905300_+	LTA synthase family protein	W6LM83	Streptococcus_phage	6.1e-151	46.9
WP_003564091.1\|905492_905933_+	transcriptional repressor	NA	NA	NA	NA
WP_003569415.1\|911992_912640_-	hypothetical protein	NA	NA	NA	NA
WP_003564111.1\|912820_914005_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.5e-141	66.0
WP_003564114.1\|914118_915612_+	MFS transporter	NA	NA	NA	NA
WP_012491224.1\|915706_916177_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003569431.1\|916420_917899_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003598039.1\|917895_918621_+	DUF4811 domain-containing protein	NA	NA	NA	NA
WP_003578172.1\|918721_919405_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_080513725.1\|919380_919578_+	hypothetical protein	NA	NA	NA	NA
919453:919469	attL	NA	NA	NA	NA
WP_003578174.1\|919983_922395_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	68.4
WP_003661367.1\|922463_922574_+	hypothetical protein	NA	NA	NA	NA
WP_003564130.1\|922660_924304_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_012491225.1\|924308_925019_+	16S rRNA pseudouridine(516) synthase	NA	NA	NA	NA
WP_003569458.1\|925161_925377_+	DNA-binding protein	NA	NA	NA	NA
WP_003569460.1\|925493_926315_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_012491226.1\|926311_926815_-	NUDIX hydrolase	NA	NA	NA	NA
WP_012491227.1\|927138_928278_-\|integrase	site-specific integrase	A0A0P0IXL3	Lactobacillus_phage	2.4e-218	100.0
WP_003598052.1\|928395_929463_-	Abi family protein	A0A0N7IRA5	Lactobacillus_phage	1.1e-207	100.0
WP_003598055.1\|929607_930039_-	hypothetical protein	A0A0P0IJV8	Lactobacillus_phage	6.8e-73	100.0
WP_012491228.1\|930108_930591_-	hypothetical protein	A0A0P0IZP3	Lactobacillus_phage	2.1e-83	100.0
WP_003598059.1\|930594_930888_-	hypothetical protein	A0A0P0HRW5	Lactobacillus_phage	5.7e-47	100.0
WP_012491229.1\|931071_931932_-	ImmA/IrrE family metallo-endopeptidase	A0A0P0IV64	Lactobacillus_phage	2.8e-158	100.0
WP_012491230.1\|931918_932287_-	helix-turn-helix domain-containing protein	A0A0P0I3L3	Lactobacillus_phage	2.8e-59	100.0
WP_003578190.1\|932542_932740_+	hypothetical protein	A0A0P0IK60	Lactobacillus_phage	5.2e-28	100.0
WP_012491231.1\|932736_933459_+	Rha family transcriptional regulator	A0A0P0IDD0	Lactobacillus_phage	1.4e-126	100.0
WP_014951753.1\|933466_933679_+	hypothetical protein	A0A0N7IRA6	Lactobacillus_phage	7.8e-30	100.0
WP_003657835.1\|933787_934012_+	DUF771 domain-containing protein	A0A0P0IQT9	Lactobacillus_phage	2.6e-39	100.0
WP_012491232.1\|934011_934104_+	hypothetical protein	A0A0P0I7S8	Lactobacillus_phage	1.2e-11	100.0
WP_012491233.1\|934100_934313_+	hypothetical protein	A0A0P0IXL9	Lactobacillus_phage	2.5e-36	100.0
WP_012491234.1\|934322_935198_+	hypothetical protein	A0A0P0IJW5	Lactobacillus_phage	1.1e-170	100.0
WP_012491235.1\|935200_935395_+	hypothetical protein	A0A0P0IZQ2	Lactobacillus_phage	2.5e-30	100.0
WP_012491236.1\|935394_936282_+	DNA recombination protein RecT	A0A0P0HRX2	Lactobacillus_phage	8.6e-163	100.0
WP_012491237.1\|936290_936536_+	helix-turn-helix transcriptional regulator	A0A0P0IV68	Lactobacillus_phage	2.6e-37	100.0
WP_012491238.1\|936540_937386_+	DnaD domain protein	A0A0N7IRA7	Lactobacillus_phage	1.0e-133	100.0
WP_012491239.1\|937423_938245_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.1e-155	100.0
WP_012491240.1\|938241_938541_+	hypothetical protein	A0A0P0IK66	Lactobacillus_phage	2.1e-49	100.0
WP_014566466.1\|938503_938788_+	hypothetical protein	A0A0P0IDD7	Lactobacillus_phage	8.8e-45	100.0
WP_014566751.1\|938756_939104_+	hypothetical protein	A0A0P0IQU7	Lactobacillus_phage	1.5e-62	100.0
WP_012491243.1\|939096_939675_+	HNH endonuclease	A0A0P0I7T6	Lactobacillus_phage	1.1e-105	100.0
WP_012491244.1\|939688_940111_+	RusA family crossover junction endodeoxyribonuclease	A0A0P0IXM5	Lactobacillus_phage	5.5e-75	100.0
WP_012491245.1\|940115_940379_+	hypothetical protein	A0A0P0IJX1	Lactobacillus_phage	6.1e-40	100.0
WP_012491246.1\|940402_940726_+	hypothetical protein	A0A0N7IRA8	Lactobacillus_phage	9.7e-56	100.0
WP_012491247.1\|940804_941254_+	hypothetical protein	A0A0P0IZR0	Lactobacillus_phage	1.2e-80	100.0
WP_012491248.1\|941478_941859_+	HNH endonuclease	A0A0P0HRY0	Lactobacillus_phage	2.5e-71	100.0
WP_003582259.1\|941928_942303_+	hypothetical protein	A0A1B0YE76	Lactobacillus_phage	3.6e-62	100.0
WP_012491250.1\|942305_944036_+\|terminase	terminase large subunit	A0A0P0IJU3	Lactobacillus_phage	0.0e+00	100.0
WP_012491251.1\|944054_945290_+\|portal	phage portal protein	A0A0P0IZM3	Lactobacillus_phage	2.6e-234	100.0
WP_012491252.1\|945267_945975_+\|protease	Clp protease ClpP	A0A0P0HRU7	Lactobacillus_phage	7.2e-128	100.0
WP_012491253.1\|945979_947209_+\|capsid	phage major capsid protein	A0A0P0IV50	Lactobacillus_phage	7.3e-229	100.0
WP_012491254.1\|947282_947531_+	hypothetical protein	A0A0P0I3K0	Lactobacillus_phage	9.1e-38	100.0
WP_003582271.1\|947544_947871_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B0Y2R7	Lactobacillus_phage	7.0e-54	100.0
WP_012491255.1\|947809_948148_+\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	2.2e-58	100.0
WP_012491256.1\|948131_948461_+	hypothetical protein	A0A0P0IDB8	Lactobacillus_phage	3.1e-57	100.0
WP_012491257.1\|948450_948834_+	hypothetical protein	A0A0P0IQS9	Lactobacillus_phage	4.5e-68	100.0
WP_012491258.1\|948845_949493_+	hypothetical protein	A0A0P0I7R6	Lactobacillus_phage	1.5e-119	100.0
WP_012491259.1\|949569_949935_+	hypothetical protein	A0A0P0IXK4	Lactobacillus_phage	4.6e-62	100.0
WP_012491260.1\|950196_953169_+	tape measure protein	A0A0P0IZN3	Lactobacillus_phage	1.3e-292	100.0
WP_012491261.1\|953175_953871_+	hypothetical protein	A0A0P0HRV6	Lactobacillus_phage	8.3e-129	100.0
WP_014566469.1\|953867_958274_+	hypothetical protein	A0A0N7IRA4	Lactobacillus_phage	0.0e+00	100.0
WP_012491263.1\|958302_958728_+	DUF1617 family protein	A0A1B0Y2S1	Lactobacillus_phage	8.8e-73	100.0
WP_012491264.1\|958730_959000_+	hypothetical protein	A0A0P0I3K6	Lactobacillus_phage	2.4e-39	100.0
WP_012491265.1\|959045_959339_+	hypothetical protein	A0A0P0IK41	Lactobacillus_phage	4.0e-48	100.0
WP_012491266.1\|959328_959763_+\|holin	phage holin	A0A0P0IDC6	Lactobacillus_phage	7.4e-51	100.0
WP_012491267.1\|959762_959951_+	hypothetical protein	A0A0P0IQT6	Lactobacillus_phage	6.7e-25	100.0
WP_012491268.1\|959937_960912_+	N-acetylmuramoyl-L-alanine amidase	A0A0P0I7S1	Lactobacillus_phage	9.1e-198	100.0
965977:965993	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1018034 : 1076511

Lactobacillus_phage(87.04%)

capsid,tail,holin,integrase,terminase,portal,head,protease

attL 1041685:1041703|attR 1076593:1076611

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003564220.1\|1018034_1018370_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_003564222.1\|1018561_1019521_+	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_003578277.1\|1019522_1020350_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_003583985.1\|1020360_1021416_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_012491289.1\|1021481_1022435_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	8.9e-81	47.9
WP_012491290.1\|1023018_1024746_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.3e-182	54.9
WP_003569557.1\|1024980_1025628_+	response regulator transcription factor	NA	NA	NA	NA
WP_014566477.1\|1025620_1026631_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_014566756.1\|1027401_1029768_+	ABC transporter permease	NA	NA	NA	NA
WP_003564240.1\|1029925_1030573_+	HD domain-containing protein	NA	NA	NA	NA
WP_003578292.1\|1030778_1032794_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_012491295.1\|1033061_1035953_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.9e-307	56.2
WP_101511963.1\|1036045_1036246_+	hypothetical protein	NA	NA	NA	NA
WP_003564246.1\|1036304_1036844_+	membrane protein	NA	NA	NA	NA
WP_003564248.1\|1037006_1037894_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.1e-08	31.4
WP_003564250.1\|1037890_1038919_+	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	2.3e-90	51.2
WP_012491296.1\|1038923_1039871_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	9.2e-54	40.7
WP_003564253.1\|1040256_1040712_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003564255.1\|1040828_1041419_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.1e-52	52.3
1041685:1041703	attL	NA	NA	NA	NA
WP_012491297.1\|1041823_1042975_-\|integrase	tyrosine-type recombinase/integrase	Q8W767	Lactobacillus_phage	2.2e-219	100.0
WP_012491298.1\|1043085_1043847_-	hypothetical protein	A0A1B0YA83	Lactobacillus_phage	1.2e-144	100.0
WP_012491299.1\|1043865_1044096_+	hypothetical protein	U5U783	Lactobacillus_phage	7.2e-37	100.0
WP_080513755.1\|1044164_1044260_-	hypothetical protein	NA	NA	NA	NA
WP_012491300.1\|1044351_1045131_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	9.1e-116	100.0
WP_012491301.1\|1045202_1045607_-	ImmA/IrrE family metallo-endopeptidase	A0A1B0Y2S4	Lactobacillus_phage	2.1e-76	100.0
WP_012491302.1\|1045603_1045930_-	helix-turn-helix transcriptional regulator	A0A1B0Y3N1	Lactobacillus_phage	3.4e-56	100.0
WP_012491303.1\|1046186_1046399_+	helix-turn-helix transcriptional regulator	A0A1B0YC38	Lactobacillus_phage	3.7e-32	100.0
WP_012491304.1\|1046401_1047175_+	ORF6N domain-containing protein	A0A1B0YEA7	Lactobacillus_phage	1.3e-143	100.0
WP_012491305.1\|1047206_1047530_+	DUF771 domain-containing protein	A0A1B0Y6D5	Lactobacillus_phage	1.2e-58	100.0
WP_012491308.1\|1047797_1048109_-	hypothetical protein	A0A1B0YA89	Lactobacillus_phage	8.2e-52	100.0
WP_012491309.1\|1048169_1048361_+	hypothetical protein	A0A1B0Y2S8	Lactobacillus_phage	6.4e-31	100.0
WP_012491310.1\|1048374_1048614_+	hypothetical protein	A0A1B0Y2S6	Lactobacillus_phage	7.7e-34	100.0
WP_012491311.1\|1048618_1049113_+	siphovirus Gp157 family protein	A0A1B0Y2S7	Lactobacillus_phage	9.9e-84	100.0
WP_012491312.1\|1049124_1049355_+	hypothetical protein	A0A1B0Y3N2	Lactobacillus_phage	3.0e-35	100.0
WP_012491313.1\|1049354_1050722_+	DEAD/DEAH box helicase	A0A1B0YC45	Lactobacillus_phage	1.6e-264	100.0
WP_012491314.1\|1050723_1051464_+	AAA family ATPase	A0A1B0YEB5	Lactobacillus_phage	4.1e-134	100.0
WP_012491315.1\|1051466_1051976_+	hypothetical protein	A0A1B0Y6E2	Lactobacillus_phage	4.1e-93	100.0
WP_012491316.1\|1052042_1052840_+	DNA primase	A0A1B0Y4T1	Lactobacillus_phage	1.4e-151	100.0
WP_012491317.1\|1052844_1054080_+	helicase	A0A1B0Y896	Lactobacillus_phage	1.1e-237	100.0
WP_012491318.1\|1054354_1054669_+	VRR-NUC domain-containing protein	A0A1B0YA93	Lactobacillus_phage	1.4e-54	100.0
WP_012491319.1\|1054675_1054960_+	hypothetical protein	A0A1B0Y2T1	Lactobacillus_phage	6.8e-45	100.0
WP_014951787.1\|1054928_1055276_+	hypothetical protein	A0A1B0Y2S9	Lactobacillus_phage	2.2e-58	99.1
WP_012491321.1\|1055268_1055856_+	HNH endonuclease	A0A1B0Y2T0	Lactobacillus_phage	9.9e-107	100.0
WP_012491322.1\|1055842_1056097_+	hypothetical protein	A0A1B0Y3N3	Lactobacillus_phage	2.3e-44	100.0
WP_012491323.1\|1056093_1056498_+	transcriptional regulator	A0A1B0YC57	Lactobacillus_phage	9.3e-72	100.0
WP_012491324.1\|1056662_1057043_+	HNH endonuclease	A0A1B0YEC6	Lactobacillus_phage	1.5e-71	100.0
WP_003582259.1\|1057111_1057486_+	hypothetical protein	A0A1B0YE76	Lactobacillus_phage	3.6e-62	100.0
WP_012491326.1\|1057488_1059219_+\|terminase	terminase large subunit	A0A1B0Y6B8	Lactobacillus_phage	0.0e+00	100.0
WP_012491327.1\|1059237_1060473_+\|portal	phage portal protein	A0A1B0Y4Q9	Lactobacillus_phage	1.2e-234	100.0
WP_012491328.1\|1060450_1061158_+\|protease	Clp protease ClpP	A0A1B0Y857	Lactobacillus_phage	1.4e-128	100.0
WP_012491329.1\|1061162_1062392_+\|capsid	phage major capsid protein	A0A1B0YA73	Lactobacillus_phage	4.3e-229	100.0
WP_012491330.1\|1062465_1062714_+	hypothetical protein	A0A1B0Y2R9	Lactobacillus_phage	7.0e-38	100.0
WP_003582271.1\|1062727_1063054_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B0Y2R7	Lactobacillus_phage	7.0e-54	100.0
WP_012491255.1\|1062992_1063331_+\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	2.2e-58	100.0
WP_012491331.1\|1063314_1063644_+	hypothetical protein	A0A1B0Y3M9	Lactobacillus_phage	3.1e-57	100.0
WP_012491332.1\|1063633_1064017_+	hypothetical protein	A0A1B0YC24	Lactobacillus_phage	2.6e-68	100.0
WP_012491333.1\|1064028_1064676_+	hypothetical protein	A0A1B0Y6C3	Lactobacillus_phage	1.2e-118	100.0
WP_003595114.1\|1064752_1065118_+	hypothetical protein	A0A1B0Y865	Lactobacillus_phage	4.6e-62	100.0
WP_014566481.1\|1065379_1068550_+	hypothetical protein	A0A1B0YA78	Lactobacillus_phage	0.0e+00	99.9
WP_012491336.1\|1068556_1069252_+	hypothetical protein	A0A1B0Y2S2	Lactobacillus_phage	8.3e-129	100.0
WP_012491337.1\|1069248_1073652_+	hypothetical protein	A0A1B0Y2S0	Lactobacillus_phage	0.0e+00	100.0
WP_012491263.1\|1073680_1074106_+	DUF1617 family protein	A0A1B0Y2S1	Lactobacillus_phage	8.8e-73	100.0
WP_012491338.1\|1074108_1074378_+	hypothetical protein	A0A1B0Y3N0	Lactobacillus_phage	1.3e-40	100.0
WP_012491339.1\|1074425_1074812_+	hypothetical protein	A0A1B0YC31	Lactobacillus_phage	5.6e-66	100.0
WP_004562059.1\|1074792_1074999_+	hypothetical protein	A0A1B0YE97	Lactobacillus_phage	1.4e-12	100.0
WP_012491341.1\|1074995_1075457_+\|holin	phage holin	A0A1B0Y6C9	Lactobacillus_phage	1.2e-70	100.0
WP_012491342.1\|1075458_1076511_+	N-acetylmuramoyl-L-alanine amidase	A0A1B0Y4R9	Lactobacillus_phage	2.3e-207	100.0
1076593:1076611	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1246889 : 1292879

Lactobacillus_phage(98.21%)

capsid,tail,holin,integrase,terminase,portal,transposase,head

attL 1242146:1242159|attR 1255468:1255481

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1242146:1242159	attL	NA	NA	NA	NA
WP_012491423.1\|1246889_1248074_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	6.6e-227	100.0
WP_012491424.1\|1248202_1248532_-	hypothetical protein	A0A0P0IJW6	Lactobacillus_phage	1.7e-39	100.0
WP_012491425.1\|1248524_1248983_-	hypothetical protein	A0A0P0ID57	Lactobacillus_phage	1.2e-86	100.0
WP_012491426.1\|1249056_1249260_-	hypothetical protein	A0A0P0IQK8	Lactobacillus_phage	8.5e-34	100.0
WP_012491427.1\|1249283_1249709_-	pyridoxamine 5'-phosphate oxidase family protein	A0A0P0I7K6	Lactobacillus_phage	9.8e-64	100.0
WP_012491428.1\|1249807_1250701_-	hypothetical protein	A0A1B0YE50	Lactobacillus_phage	4.3e-162	100.0
WP_014566771.1\|1250751_1252095_-	DUF4041 domain-containing protein	A0A1B0Y697	Lactobacillus_phage	7.6e-195	100.0
WP_012491430.1\|1252184_1252535_-	hypothetical protein	A0A1B0Y4P2	Lactobacillus_phage	3.3e-57	100.0
WP_012491431.1\|1252591_1253170_-	hypothetical protein	A0A1B0Y834	Lactobacillus_phage	8.8e-108	100.0
WP_012491432.1\|1253228_1253648_-	ImmA/IrrE family metallo-endopeptidase	A0A1B0YA58	Lactobacillus_phage	1.2e-77	100.0
WP_012491433.1\|1253637_1253976_-	helix-turn-helix transcriptional regulator	A0A1B0Y2R0	Lactobacillus_phage	7.0e-57	100.0
WP_003585053.1\|1254115_1254316_+	helix-turn-helix transcriptional regulator	A0A1B0Y2Q9	Lactobacillus_phage	6.2e-29	100.0
WP_003574526.1\|1254352_1254664_+	hypothetical protein	A0A1B0Y2Q8	Lactobacillus_phage	2.2e-52	100.0
WP_016373289.1\|1254660_1254870_-	hypothetical protein	A0A1B0Y3M6	Lactobacillus_phage	1.1e-31	98.6
WP_012491435.1\|1255169_1255718_+	hypothetical protein	A0A1B0YE60	Lactobacillus_phage	1.1e-99	100.0
1255468:1255481	attR	NA	NA	NA	NA
WP_003594176.1\|1255696_1255918_+	helix-turn-helix domain-containing protein	A0A1B0Y6A3	Lactobacillus_phage	1.8e-37	100.0
WP_012491436.1\|1255930_1256059_+	hypothetical protein	A0A0P0IQL2	Lactobacillus_phage	1.7e-16	100.0
WP_014951828.1\|1256158_1256566_+	hypothetical protein	A0A1B0Y842	Lactobacillus_phage	1.1e-75	100.0
WP_012491438.1\|1256578_1257442_+	DNA recombination protein RecT	A0A1B0YA63	Lactobacillus_phage	1.1e-159	100.0
WP_014566774.1\|1257422_1258223_+	hypothetical protein	A0A0P0IZH9	Lactobacillus_phage	3.1e-143	92.5
WP_012491440.1\|1258238_1259204_+	DnaD domain protein	A0A1B0Y2R2	Lactobacillus_phage	1.3e-140	100.0
WP_012491441.1\|1259330_1259711_-	DUF2513 domain-containing protein	A0A0P0IV09	Lactobacillus_phage	1.4e-66	100.0
WP_012491442.1\|1260045_1260258_+	helix-turn-helix transcriptional regulator	A0A0P0IJY1	Lactobacillus_phage	1.3e-32	100.0
WP_012491443.1\|1260254_1260704_+	hypothetical protein	A0A0P0ID70	Lactobacillus_phage	1.2e-72	100.0
WP_012491444.1\|1260750_1261005_+	hypothetical protein	A0A0P0IQP0	Lactobacillus_phage	2.6e-40	100.0
WP_003661419.1\|1261001_1261367_+	endodeoxyribonuclease	A0A0P0I7M2	Lactobacillus_phage	1.8e-66	100.0
WP_080513756.1\|1261601_1261673_+	hypothetical protein	A0A0P0IXF6	Lactobacillus_phage	5.8e-06	100.0
WP_012491448.1\|1262246_1262690_+	autolysin regulatory protein arpU	A0A0P0IZI6	Lactobacillus_phage	1.3e-79	100.0
WP_014566775.1\|1263285_1263666_+	hypothetical protein	A0A0P0HRR1	Lactobacillus_phage	6.5e-67	100.0
WP_012491450.1\|1264174_1265323_+	hypothetical protein	A0A0P0I3G0	Lactobacillus_phage	4.6e-225	100.0
WP_016379922.1\|1265315_1265639_+	phage-related protein, ribonucleoside-diphosphate reductase	A0A0P0IJY9	Lactobacillus_phage	1.0e-57	100.0
WP_012491452.1\|1265675_1266248_+\|terminase	terminase small subunit	A0A0P0IUY4	Lactobacillus_phage	1.0e-84	100.0
WP_012491453.1\|1266231_1267485_+\|terminase	PBSX family phage terminase large subunit	A0A0P0I3B0	Lactobacillus_phage	3.5e-250	100.0
WP_012491454.1\|1267489_1268917_+\|portal	phage portal protein	A0A0P0IJV3	Lactobacillus_phage	2.8e-264	99.8
WP_012491455.1\|1268882_1269875_+	hypothetical protein	A0A0P0ID43	Lactobacillus_phage	1.6e-186	100.0
WP_012491456.1\|1269999_1270638_+	DUF4355 domain-containing protein	A0A0P0IQJ5	Lactobacillus_phage	7.2e-87	100.0
WP_003605853.1\|1270650_1270965_+	hypothetical protein	A0A0N7IR89	Lactobacillus_phage	2.7e-50	100.0
WP_012491457.1\|1270978_1272019_+\|capsid	major capsid protein	A0A0P0I7J2	Lactobacillus_phage	6.7e-191	100.0
WP_080513730.1\|1272282_1272498_-	hypothetical protein	NA	NA	NA	NA
WP_012491458.1\|1272529_1273408_+	hypothetical protein	A0A0P0IJL6	Lactobacillus_phage	5.9e-180	100.0
WP_012491459.1\|1273407_1273782_+\|head,tail	phage head-tail connector protein	A0A0P0IZF6	Lactobacillus_phage	1.0e-64	100.0
WP_012491460.1\|1273786_1274089_+	hypothetical protein	A0A0P0HRN0	Lactobacillus_phage	4.7e-52	100.0
WP_012491461.1\|1274085_1274451_+\|head,tail	phage head-tail joining protein	A0A0P0IUZ3	Lactobacillus_phage	1.6e-59	100.0
WP_003566400.1\|1274451_1274856_+	DUF3168 domain-containing protein	A0A0P0I3C8	Lactobacillus_phage	4.6e-71	100.0
WP_012491462.1\|1274867_1275467_+\|tail	phage tail protein	A0A0N7IR90	Lactobacillus_phage	6.1e-104	100.0
WP_003566397.1\|1275605_1275941_+	hypothetical protein	A0A0P0IJV9	Lactobacillus_phage	9.4e-54	100.0
WP_003595195.1\|1276039_1276393_+	hypothetical protein	A0A0P0ID51	Lactobacillus_phage	8.7e-58	100.0
WP_012491464.1\|1276385_1279721_+\|tail	phage tail tape measure protein	A0A0P0IQK3	Lactobacillus_phage	0.0e+00	100.0
WP_012491465.1\|1279723_1281688_+\|tail	phage tail protein	A0A0P0I7K0	Lactobacillus_phage	0.0e+00	100.0
WP_012491466.1\|1281684_1284804_+\|tail	phage tail protein	A0A0P0IXD5	Lactobacillus_phage	0.0e+00	100.0
WP_012491467.1\|1284813_1285137_+	hypothetical protein	A0A0P0IJM9	Lactobacillus_phage	3.5e-53	100.0
WP_003573798.1\|1285129_1285261_+	XkdX family protein	A0A0P0HRS7	Lactobacillus_phage	6.5e-19	100.0
WP_003581984.1\|1285316_1285592_+	hypothetical protein	A0A0P0IZF9	Lactobacillus_phage	7.5e-49	100.0
WP_003594199.1\|1285606_1286020_+\|holin	phage holin	A0A0N7IR91	Lactobacillus_phage	3.1e-46	100.0
WP_080513757.1\|1286093_1287215_+	LysM peptidoglycan-binding domain-containing protein	A0A0P0HRN9	Lactobacillus_phage	1.3e-216	99.7
WP_012491471.1\|1287259_1287484_+	hypothetical protein	A0A0P0IUZ5	Lactobacillus_phage	7.2e-34	100.0
WP_014951836.1\|1287602_1287767_+	hypothetical protein	NA	NA	NA	NA
WP_012491472.1\|1288125_1288905_-	DUF1829 domain-containing protein	NA	NA	NA	NA
WP_003564892.1\|1289006_1289294_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_012491473.1\|1289475_1290006_-	hypothetical protein	NA	NA	NA	NA
WP_012491474.1\|1290086_1290938_-	hypothetical protein	NA	NA	NA	NA
WP_003564898.1\|1290934_1291684_-	hypothetical protein	NA	NA	NA	NA
WP_003601683.1\|1291880_1292879_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.8e-55	39.8

DBSCAN-SWA_5

2052213 : 2074053

unidentified_phage(40.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012491745.1\|2052213_2052975_+\|protease	matrixin family metalloprotease	G9I094	Helicoverpa_zea_nudivirus	1.7e-05	53.1
WP_123796557.1\|2052879_2053116_-	hypothetical protein	NA	NA	NA	NA
WP_003599410.1\|2053142_2054072_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9
WP_012491746.1\|2054196_2054964_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_012491747.1\|2055276_2056872_+	hypothetical protein	NA	NA	NA	NA
WP_003566275.1\|2057572_2057902_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012491748.1\|2058278_2058923_+	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_012491750.1\|2060472_2061117_-	hypothetical protein	NA	NA	NA	NA
WP_012491751.1\|2061097_2061388_-	hypothetical protein	NA	NA	NA	NA
WP_123796558.1\|2061817_2062604_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_012491754.1\|2063302_2063824_-	hypothetical protein	NA	NA	NA	NA
WP_101869771.1\|2063996_2065113_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.0e-27	32.6
WP_003595460.1\|2066372_2067281_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_003599410.1\|2067564_2068494_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9
WP_071665477.1\|2068520_2068601_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_012491757.1\|2068607_2069504_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_014566584.1\|2069507_2070365_-	peptidase	NA	NA	NA	NA
WP_012491759.1\|2070364_2071450_-	M42 family peptidase	NA	NA	NA	NA
WP_012491760.1\|2071478_2073098_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002816607.1\|2073369_2074053_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8

DBSCAN-SWA_6

3031391 : 3042760

uncultured_Caudovirales_phage(37.5%)

capsid,tail,terminase,portal,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012492208.1\|3031391_3032030_-	helix-turn-helix domain-containing protein	L0P7E1	Lactobacillus_phage	2.4e-05	27.6
WP_003594046.1\|3032197_3032473_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012492209.1\|3032540_3032762_+	hypothetical protein	NA	NA	NA	NA
WP_012492211.1\|3032872_3033064_+	hypothetical protein	NA	NA	NA	NA
WP_012492212.1\|3033110_3033401_+	hypothetical protein	NA	NA	NA	NA
WP_014566704.1\|3033397_3033586_+	hypothetical protein	NA	NA	NA	NA
WP_014566705.1\|3033569_3034382_+	DNA replication protein	Q854C1	Mycobacterium_phage	6.7e-13	34.2
WP_012492215.1\|3034394_3035981_+	primase	A0A1B1P7L5	Bacillus_phage	4.0e-25	27.9
WP_012492216.1\|3036306_3036642_+\|head	phage head closure protein	NA	NA	NA	NA
WP_012492217.1\|3036646_3036832_+	hypothetical protein	NA	NA	NA	NA
WP_014952495.1\|3036828_3037251_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	1.2e-21	45.4
WP_010489224.1\|3037367_3037838_+\|terminase	phage terminase small subunit P27 family	M1PKP2	Streptococcus_phage	4.6e-06	26.5
WP_012492218.1\|3037834_3039538_+\|terminase	terminase	A0A2H4JBN3	uncultured_Caudovirales_phage	2.3e-116	42.1
WP_014952496.1\|3039503_3039683_+	hypothetical protein	NA	NA	NA	NA
WP_010489222.1\|3039687_3040869_+\|portal	phage portal protein	A0A2H4JB06	uncultured_Caudovirales_phage	2.8e-60	35.5
WP_012492220.1\|3040855_3042412_+\|capsid	phage major capsid protein	A0A2H4J9X8	uncultured_Caudovirales_phage	4.6e-34	32.0
WP_003574397.1\|3042466_3042760_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP038154

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1711 : 49071

Staphylococcus_phage(35.71%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003568776.1\|1711_1831_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_002816607.1\|2189_2873_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
WP_014566854.1\|2913_3162_-	hypothetical protein	NA	NA	NA	NA
WP_014566855.1\|3380_3656_-	hypothetical protein	NA	NA	NA	NA
WP_014566856.1\|3642_3873_-	hypothetical protein	NA	NA	NA	NA
WP_014566857.1\|3865_4084_-	hypothetical protein	NA	NA	NA	NA
WP_014566858.1\|4091_4328_-	hypothetical protein	NA	NA	NA	NA
WP_014566859.1\|4854_5082_-	hypothetical protein	NA	NA	NA	NA
WP_014566860.1\|5575_6313_-	hypothetical protein	NA	NA	NA	NA
WP_014566861.1\|6302_7358_-	replication initiator protein A	NA	NA	NA	NA
WP_014566862.1\|7748_8585_+	ParA family protein	F0PIG8	Enterococcus_phage	1.1e-37	36.7
WP_014566863.1\|8577_8967_+	hypothetical protein	NA	NA	NA	NA
WP_014566897.1\|9011_9353_-	hypothetical protein	NA	NA	NA	NA
WP_014566865.1\|9345_10638_-	Y-family DNA polymerase	O64031	Bacillus_phage	1.3e-79	39.9
WP_015338164.1\|10634_11018_-	hypothetical protein	NA	NA	NA	NA
WP_003572740.1\|11211_11529_+	hypothetical protein	NA	NA	NA	NA
WP_123796560.1\|11764_12927_-\|transposase	IS3-like element ISL1 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.1e-30	33.2
WP_150891370.1\|19266_21270_+	collagen binding domain-containing protein	NA	NA	NA	NA
WP_014566870.1\|21594_21846_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	1.5e-35	92.8
WP_080555491.1\|23028_23226_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014566873.1\|23425_23893_-	hypothetical protein	NA	NA	NA	NA
WP_003601979.1\|24166_24817_+	recombinase family protein	M9Q1K0	Clostridium_phage	1.5e-18	37.6
WP_002819966.1\|24822_25107_+	hypothetical protein	NA	NA	NA	NA
WP_126139134.1\|25168_25955_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_003606765.1\|25942_26266_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_014566439.1\|26621_27500_+	PRD domain-containing protein	NA	NA	NA	NA
WP_014951697.1\|27620_29354_+	PTS lactose transporter subunit IICB	NA	NA	NA	NA
WP_003589794.1\|29380_30805_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
WP_003589792.1\|30853_31189_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_003586333.1\|32668_33226_-	serine acetyltransferase	NA	NA	NA	NA
WP_003586331.1\|33191_34376_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_012807380.1\|34397_35309_-	cysteine synthase family protein	A0A1W6JIM2	Lactococcus_phage	2.8e-60	41.7
WP_016387670.1\|36052_39220_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.1e-21	22.6
WP_014566850.1\|39233_40850_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.3e-127	50.3
WP_015338155.1\|40846_41473_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.4e-10	30.0
WP_123827224.1\|41540_42327_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_014566853.1\|42335_42695_-	hypothetical protein	NA	NA	NA	NA
WP_003582052.1\|42700_43594_-	non-specific DNA/RNA endonuclease	NA	NA	NA	NA
WP_002816607.1\|43683_44367_+\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8
WP_014566892.1\|44703_45534_-	ATP-dependent sacrificial sulfur transferase LarE	NA	NA	NA	NA
WP_003643656.1\|45558_46275_-	aquaporin family protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	4.1e-22	33.6
WP_029327658.1\|46279_47542_-	nickel pincer cofactor biosynthesis protein LarC	NA	NA	NA	NA
WP_014566890.1\|47572_48313_-	nickel pincer cofactor biosynthesis protein LarB	A0A288TYA6	Enterococcus_phage	4.7e-21	47.2
WP_002816607.1\|48387_49071_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	2.1e-60	51.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP038153

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP038154

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection