CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP032518	Cupriavidus oxalaticus strain T2 chromosome 1, complete sequence	1 crisprs	RT,csa3,DEDDh	0	1
NZ_CP032519	Cupriavidus oxalaticus strain T2 chromosome 2, complete sequence	1 crisprs	cas3,RT,DinG,WYL,DEDDh,csa3	0	6
NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	1 crisprs	PD-DExK,PrimPol,RT	5	3

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP032518_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP032518_1

1657084-1657219

Orphan

Consensus_repeat	Method
CGCAGAAACGGGTACGCCTACCGC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP032518_1

>merge|NZ_CP032518|1|1657084-1657219|PILER-CR
CGCAGAAACTGGTACGCCTTGCTGCGCTGCAAGCCGGGACTGCCGGCCGCCGGCTTGCGCAGAAACGGGTACGCCCACCGCCAACCAAGACCCGTCGACATACCGGGGGGCACGCAGAAACGGGTACGCCTGGCGC

>NZ_CP032518|1|1|1657084-1657219|PILER-CR
CGCAGAAACTGGTACGCCTTGCTG	CGCTGCAAGCCGGGACTGCCGGCCGCCGGCTTGCGCAG
AAACGGGTACGCCCACCGCCAACC	AAGACCCGTCGACATACCGGGGGGCACGCAG
AAACGGGTACGCCTGGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP032518.1\|WP_063237646.1\|1658473_1659568_+\|replication-protein-RepA	unknown	unknown	gnl\|CDD\|309782
NZ_CP032518.1\|WP_006159056.1\|1659679_1659883_-\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP032518.1\|WP_151070136.1\|1643496_1645656_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227113
NZ_CP032518.1\|WP_151070143.1\|1664372_1665185_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP032518.1\|WP_063237638.1\|1641885_1643133_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP032518.1\|WP_151070141.1\|1653035_1654400_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP032518.1\|WP_151069397.1\|1655501_1656878_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NZ_CP032518.1\|WP_151070140.1\|1651777_1652251_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032518.1\|WP_151070147.1\|1668069_1668864_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032518.1\|WP_151070146.1\|1667107_1668073_+\|DUF1839-family-protein	unknown	unknown	gnl\|CDD\|370175
NZ_CP032518.1\|WP_151070144.1\|1665505_1665970_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP032518.1\|WP_151070142.1\|1662100_1663765_-\|integrase	unknown	unknown	gnl\|CDD\|372139
NZ_CP032518.1\|WP_063237642.1\|1649739_1650147_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032518.1\|WP_063237647.1\|1660264_1660924_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224113
NZ_CP032518.1\|WP_151070139.1\|1650284_1651652_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP032518.1\|WP_151070145.1\|1666128_1666407_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032518.1\|WP_010811149.1\|1654818_1655022_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP032518.1\|WP_063237648.1\|1660927_1661941_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|224392
NZ_CP032518.1\|WP_063237640.1\|1645727_1647341_-\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NZ_CP032518.1\|WP_116386962.1\|1647466_1648402_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214

Protein	Function_ID	Function_description	E-value
NZ_CP032518.1\|WP_063237646.1\|1658473_1659568_+\|replication-protein-RepA	gnl\|CDD\|309782	pfam04796, RepA_C, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood.	7.1063e-32
NZ_CP032518.1\|WP_006159056.1\|1659679_1659883_-\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.67013e-36
NZ_CP032518.1\|WP_151070136.1\|1643496_1645656_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227113	COG4772, FecA, Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism].	0
NZ_CP032518.1\|WP_151070143.1\|1664372_1665185_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.43551e-26
NZ_CP032518.1\|WP_063237638.1\|1641885_1643133_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.78517e-76
NZ_CP032518.1\|WP_151070141.1\|1653035_1654400_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.62707e-174
NZ_CP032518.1\|WP_151069397.1\|1655501_1656878_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	5.82444e-180
NZ_CP032518.1\|WP_151070144.1\|1665505_1665970_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.96348e-06
NZ_CP032518.1\|WP_151070142.1\|1662100_1663765_-\|integrase	gnl\|CDD\|372139	pfam12482, DUF3701, Phage integrase protein. This domain family is found in bacteria, and is approximately 100 amino acids in length. The family is found in association with pfam00589.	8.65762e-12
NZ_CP032518.1\|WP_151070146.1\|1667107_1668073_+\|DUF1839-family-protein	gnl\|CDD\|370175	pfam08893, DUF1839, Domain of unknown function (DUF1839). This family of proteins are functionally uncharacterized.	6.99143e-158
NZ_CP032518.1\|WP_063237647.1\|1660264_1660924_+\|AAA-family-ATPase	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.42462e-38
NZ_CP032518.1\|WP_151070139.1\|1650284_1651652_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.94699e-144
NZ_CP032518.1\|WP_010811149.1\|1654818_1655022_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.31341e-34
NZ_CP032518.1\|WP_063237648.1\|1660927_1661941_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|224392	COG1475, Spo0J, Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription].	1.18855e-22
NZ_CP032518.1\|WP_063237640.1\|1645727_1647341_-\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NZ_CP032518.1\|WP_116386962.1\|1647466_1648402_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	1.59379e-46

>NZ_CP032518.1|WP_151069397.1|1655501_1656878_+|group-II-intron-reverse-transcriptase/maturase
MEAQQKTHRGLEQGRRGEAPTPGPRGAESMAANPETESPSVTDRLMEAICEPENLRQALKRVKANKGAPGVDGMTVKELPGYLKSHWAGLREQLLSGTYKAQPVRRVEIPKPDGGIRKLGVPTARDRFIQQALMQVLQRQWDPTFSDASYGFRPGRSAHQAVARAQGHIEAGCKWVVDLDLEKFFDRVNHDLLMSRVAKRVSDKRVLKLIRGFLTSGVLEQGLVGPTDEGTPQGGPLSPLLSNLLLDDLDRELERRGLRFVRYADDCNVYVRSERAGQRVMRGLKAYLIDKLKLKVNESKSAVAPPAERKFLGFTFRLTTRVWRVIAPQSVGRFKEKVRELTRRSRGISLERMLAELRRYLIGWLGYFGFNEWPSVLRDVEGWLRRRLRCFLWKQWKVSPARFRELRGRGIGPDLAAQTVGSPHGPWRLSCSPALNMALPNRFFDELGLPSLVRKPIN
>NZ_CP032518.1|WP_010811149.1|1654818_1655022_+|cold-shock-protein
MQTGIVKWFNDAKGFGFIKPDAGGDDLFAHFSEIRADGFKSLQENQRVQFEVKNGPKGLQAANITPL
>NZ_CP032518.1|WP_151070141.1|1653035_1654400_-|NCS2-family-permease
MSTPEPASKPGTPSVNPSRGQPALLERLFKLREHQTDVRTEVLAGITTFLTMAYILFVNPSILGDAGMPKDAVFVATCVAAAIGTLIMGFYANYPIAMAPGMGLNAYFAYTVVKGMGFPWEAALGAVFISGCLFLLVTLFRVREMIVNGIPHSIRVAITAGIGLFLAIVALKNAGIVAASPATLVTLGDLHQPPAVLAIVGFFVIVALDHLRVKGAILIGILLTTLLSFAFAGNTFHGVFSAPPSLSPTLLKLDISAALSIGIINVVLVFFLVELFDATGTLMGVANRAGLLKAGRMDRLNKALMADSTAIMAGSFLGTSSTTAYIESASGVQAGGRTGLTAVTVAVLFLAALFIAPLAGTVPAYATAPALLYVSCLMLRELLEIDWNDVTEVVPAVMTALGMPFTYSVANGVAFGFISYAALKLLTGRARSVPVMVWFIAAVFVFKFYYLPGH
>NZ_CP032518.1|WP_151070140.1|1651777_1652251_-|hypothetical-protein
MTAGEIRRPAIGPVRESISRSTSRSIHHAWAALGEAAGEAPANRASHDSAAADVAALLADDSALSDHARAAVENLLRRHRLLEGELARQRAMLQEWILSQLTYKSLYYQYSGQTPEAPRVELMREKEAVRRRIREQLQGGSGYLAAPEEPSRSLSTS
>NZ_CP032518.1|WP_151070139.1|1650284_1651652_-|sigma-54-interacting-transcriptional-regulator
MDRLCKASRTAQIVVVSRHEDFGFDPSSFGPGWELRRVQQIRDVERVVRASPPTAGVIDLQAEYSDAELGQLELALQHLHVTWVAITCDAMLADERVRRLIRDYCVDYVRTPFSVEELIYTLKHAHGMASLHGARVQETAPRGTMIGECAAMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHDASSRRKGPFIAINCGAIPSHLVQSELFGYEKGAFTGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGTITRLGGHQSIPLNLRIISATHVDLVAAQGDGRFRSDLFHRLCVLTLSIPPLRERGEDILQLANAVLAEHGHEAHRRIRGFSACATQAMMQYAWPGNVRELINRVRRAIVMTDNRKITAEDLQLHGGAELPRKTLDAIREEAEREAIRNVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVESQPAAGE
>NZ_CP032518.1|WP_063237642.1|1649739_1650147_+|hypothetical-protein
MKAANPAAGVLAALAVFSAPAVAASYAWFDRPDDASANSHAAVSNDVYVRGFGWAWGELHMQQDTSPGAGAPAAPQGGRQARDYPDRRDAPPWLQRDDNGPPRMPRGKISMNLAAAPADGAIGGSGAGQPRAVAR
>NZ_CP032518.1|WP_116386962.1|1647466_1648402_-|YihY/virulence-factor-BrkB-family-protein
MPDRHTGARTLRVVTAAVASWFDHRAASKGAALSFYMLFSLAPILVLVISIAGLFFGAEAARGEIFTQIEGLVGEQGATAIQQILAATHRAGGSGMAALIAMGILFVGATSAFAELKSSLDDIWHVPVPKTAGWQTLLRARLLSFSLVLVLAFMLLVSLIVNAALAVVERIWGQLWTQSWFAPVADVISTAFSFAVVTALFAVIFKMLPNARIAWRDVTMGAIITALLFSVGKRLIGLYLGNSAVASSYGAAGSVVALMLWIYYSAQIFFFGAELTRQYALQFGSLRGVPGMGGEGDGKGEGKPPAWPANR
>NZ_CP032518.1|WP_063237640.1|1645727_1647341_-|peptide-chain-release-factor-3
MSSLVSEIARRRTFAIISHPDAGKTTLTEKLLWFGGAIQVAGEVRARKADRHATSDWMELEKQRGISVTSSVMQFPYGRGDANNSADGNAQENIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRDTPILTFINKLDREGRSPIELLDEIEDVLQIQCAPMTWPIGMGKQFRGVYHLIDDKVQLFDPKGEKGTAAILDGLDNPELDRILGSQADELRVEIELVRGASHTFDKEAFRAGKQTPVYFGSAINNFGVQSLLDALCELSPPPLARNTDTRVVEPNEGKFTGFVFKIQANMDPRHRDRIAFVRVCSGRFERGMKLLHVSAGKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDVFTEGEPLKFTGIPSFAPEFFRRARLNNPLKVKQLQKGLQQLAEEGATQMFRPLVSNDLVLGAVGILQFDVVAHRLEHEYGVDAIFESHECATARWLKGSPAEIEKLIAKAGHNVALDGAGDHVYLAPSMVNLRLTQERFPELQFLETREIV
>NZ_CP032518.1|WP_151070136.1|1643496_1645656_+|TonB-dependent-siderophore-receptor
MQPAFRLTAGAIGAALLFALPAHAQTAATAPAAGSASAETTLNAVTVVGNWLENADEAKVLEHPGARTIVDRETFQEAGANNVREVLRRVPGVQVQENNGTGGSDVSLNVGVRGLTARLSPRSTILMDGVPLAVAPYGQPQLSMAPLSLGNLESIDVVRGAGSVRYGPQNVGGIINFATRSIPQTFAADASVSTDLYSHGGNVKTNPTAFIGGTNDNGLGGALLYSGIHGNGYRESNDHVNIDDLLLKGNYRISKTDELSAAFHYYEGRAGMPGGLTPAQYAADPFQSVRPYDNFDGRRSDVSLKYSHNDNNRKFEVLTYYTDSFRGSNIEQQGTGASANLRRLTSAPRNYHTFAIEPRYSQLFRGENMSHEVSVGYRFLREASDEKASRTVFYTPGTIDPTTLPSPVYQSRTGGTTANAVYIDDTINVGSWTITPGLRYEFIRSYVSDNFTGARNDVSSNEPLPSLAVMYHVSDQWKLFANAGVSFGPLQYFQIAQTTNGLTPEKAKTYEIGTHFNSNGWGGELTLFNIDFDDELQLRGGTGGAPDAWTNLGATTHRGVESSLRYDFGALDKSLAGLSAYATYTFTEATYNQGNFAGRDLPFYSRHVATVGMRYARNRWAFNIDGYAQSKQHSPGDPSTSTTYQTAESANGALGDIPGYALLNMRLGYDFGKSAQNLKVAVGVKNLFDKRYFTRSTDNNAGKYVGMPRTFYIQASLAY
>NZ_CP032518.1|WP_063237638.1|1641885_1643133_-|MFS-transporter
MSSPATVPAAEPDSVFGDAAFRRYWFARLCTTIGYQIFTVAVGWQMYDLTRDPLMLGMVGLVQFLPSVLLILMSGHVADRFDRRRIVRACQAIEALLAAGMAVASLTGWIDSHHIFVFVALIGATRAFENPTLQALLPSVVTPRQLPRAVALASSAGQTAIIIGPAIGGFAYVAGPGVVYALSATLFVIAAVLVSGITLRQAAQRLTAPVSMRTVFAGFAYIRSRPVLLGAISLDLFAVLLGGAVALLPIYARDILHTGPWGLGLLRSSPAVGALVMALWLARHPLNRRAGRIMFGAVALFGAATVVFGVSTWLPLSMVALVVLGASDMISVVVRSTLVQLDTPDDMRGRVGAVNSVFIGASNQLGEFESGVTAALFGPVGAVILGGVGTLLVVAVWMRLFPALASRDRLHEHAT
>NZ_CP032518.1|WP_063237646.1|1658473_1659568_+|replication-protein-RepA
MPIKRSPAATGDRSVLDVDAEPSRIIVPGNENSLIPSEKFQRLFDEAQAMEREDAWQSGEVGFLSRASVQVTLPYRAPKGAPPVWTRTSGNISLMIQPGYFTQQRSERATNGRQKLVSETVSLGYPYGSYPRLMLAWIGKEIMAKKKRGEFTGTVEDRRISLGNSLSEFMYNLGIPMATGGKRGTMTLVRQQMIRLFSATIAIVQNKSTPSQNQNPNHEPLSIDRVGYLLADQLSTWWDPMQPGQGSMFESFVVLSEPFFNELVNRPVPVDMRALKALKQSPFALDVYSWLTYRFFTIQRRTEIPWEALQMQFGTETESERKFRALFRKALKDVLVVYPGAKVDADSSKALILQPSRTSVRKLG
>NZ_CP032518.1|WP_006159056.1|1659679_1659883_-|cold-shock-protein
MATGTVKWFNETKGFGFITPDDGGADLFAHFSEIQGSGFKTLKDGQRVTFEVKQGPKGLQASAIKPA
>NZ_CP032518.1|WP_063237647.1|1660264_1660924_+|AAA-family-ATPase
MAAKIITVFNQKGGCGKTTVSMHLAGTLGLRGARSMLVDMDEQGTATRWAAQASDERPFPASVIGLAPSGGAMHREVRKFVQDYDYIVVDCPPAVHSAAPSSALLISDLAIIPVVPSPPDLWAAVAAKTLAQHAQVQNETLLIRVMANMVQRRVSIARQAIEILGDDGEVPLLNSMIGSRSAFRECQAIGCTVHGVAGAREAVQEVDMMVDEVLSLIEQ
>NZ_CP032518.1|WP_063237648.1|1660927_1661941_+|ParB/RepB/Spo0J-family-partition-protein
MATKLKSLKAGMLAGMVAEKHRNDTLDRFARAEAAISQHPNGLLQGRANDAAAVFSAESAGEMATGRQLVRIPLAQLHDNPLNARRIYDPAVVQERAASIATHGQKTPGLAAPDPSRPGHYILIDGHYRKRALASAGKLEMECFVEDDLSDLDFYRLSFMLNEQRSDQSALDNAIAWRQLLDEGKVQKEEEICELTGMSAGTVNKTLALLRLPESVLGVMRERPSAIGIAAGYELTLYCKLAGEERTRELAARIISDGLSSREVEAIRKHAQEGKARKVKEISRQYKIRTDSGQLLGTIKEWDSGRVVLDVQLGDRSAREDLVELLKARFGLDKTLL
>NZ_CP032518.1|WP_151070142.1|1662100_1663765_-|integrase
MLTGSHSVSLTRSEFAAVRAYVQGMPAAMVVGRYLADDGDDEDAGESALRTLLGLRDRMVQLAHLHGRADLAELLVAGPGRSNRGMDRRVDALAELERLGTAAPRAEHGVELWFGPSLARRLRDAEIVTIKSLIGLINLRGTGWWRRVPRIGAQAGQAINRWLAEHRELVRTPQGQPMLAAHVGNRAPLARGALVPGMPRLLPLELLASDAGAPPACPFACGVHVVRKWLHASAPPAGATYAAYRKEAERLLLWSAIERRKGLAALDEQDRQAYLAFLADPQPAARWCGPRAPRQTAAWRPFTGPLGDASLRHSMRVLGALWAWMARNGYDSTARWLPIGGPARDAAADIGMATGEMASAWDTGSAAGEGVVDDMALVRFTAWLENESSRTGGMRYRAAAAAVALLRECRPRIAGLVALRWKDLRVLERVPEAEAGEAPDDDRLVLSDTALAALRRHWQDRGLDLYAPAAADVPLLGPPVAPPTRRAQRKLASTAHPPYSVRGLHALLSAAITRYRRLDAAFPAWSPRELAREARHDRTTSASVEEVGTEGELP
>NZ_CP032518.1|WP_151070143.1|1664372_1665185_+|response-regulator-transcription-factor
MASILLIEQHPLLRLGLRHLLAQAHLPGDLIDIDPLAPIEPDLWLMEADLLVYGLPSDAAAGWAQLDNLCERLRPRRVLLLTERPAAALSRPALPESVRGCLHKAASAEALDAAVRLVLAGGECFPSLLLGEPASGRGDDAGTPTLSEPIAPAEPGSHAAAPVVVPLHALRGEAPGAHTSETPSSGAHLLNITERQYEVLALLARGYPIKTVSRMLNISVATAKTHACTLYQRLHVRNKGEAVYVALQRGATLDWSGPPAVRPLGACQAA
>NZ_CP032518.1|WP_151070144.1|1665505_1665970_+|response-regulator-transcription-factor
MPTYLIASNEMMCRTLVRRLEALGLPPPIRWRAPQWLQECAAHRQSRADADEPGSDPADVALIDCSGLEGDPRKLLDQMQARLAPCRWLVLSDRLDASLIVHAALLGASGCLAVPAPAELVCAATALVWAGGQCFPRMALSLMHATPQDSVGAV
>NZ_CP032518.1|WP_151070145.1|1666128_1666407_+|hypothetical-protein
MEGGMEYLVVHGFAVREGRGKWACCFEIRLAGAGEQPLLYRGELHGRRFDCEHAAAQAAHEAGQREAVLRVESLRALILAQHRLRLPAATLP
>NZ_CP032518.1|WP_151070146.1|1667107_1668073_+|DUF1839-family-protein
MRGRGGPGLRGGNPVWSHVNCHIDLWIELLHGLELPPVAALPCAVRQDFEADHFTQCRFPVADLERLYGLTSHALTLYDSLESHVAAQTARGHLVVLELDSSQLPPPPGAGYQRHRTPTCIAVDVLIPEAGAVGYYHTDGYHTASGEDYAAIFRLAPGARSAETLPFVHADVVRRDGRLRGREPLLDASLALLRTHLGNRPQQNPVTQFRAAFPAHLERLMARGEPGFHHYASGVLRQLGANFELLARYLRWLVMQGQDVPEKAAEACYTMASEAMVMQFRLMRAVISRKPDRCEDCLDQLEASYQASVPALARHFGEYAP
>NZ_CP032518.1|WP_151070147.1|1668069_1668864_+|hypothetical-protein
MTADAAATGRPAAAPVLVPAPVPLTGVTPITAVTDVAPRAPGGLWQWLQTLPGAVPSPAVLDDGACWLPAPVPGSVAMAMQAAGRLRAGAPVPLHCHDYWYRLRLAGHGPRLLRLRGLARGAEAWFNGRLVIAVDDAIGGAAGLDRLQELHGLHELYEAAIELSGMNTIHLCFRAPRVLHPAAVAARGWRCIVAASGRLAGFLPCALPLNEVGPCQPVELLAPFTLFPSLPAPVVSAGRPALPPISDFCTRARRLPAPLPRTAR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1767530 : 1830665

Acidithiobacillus_phage(40.0%)

protease,transposase,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_151070206.1\|1767530_1769468_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5ESM9	Bathycoccus_sp._RCC1105_virus	2.4e-109	46.2
WP_151070207.1\|1769589_1769853_-	hypothetical protein	NA	NA	NA	NA
WP_151070892.1\|1769887_1770553_-	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_151070208.1\|1770552_1770804_-	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_151070209.1\|1771154_1771376_-	hypothetical protein	NA	NA	NA	NA
WP_151070210.1\|1771372_1773826_-	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.0e-96	38.1
WP_151070211.1\|1774008_1775187_-	methionine adenosyltransferase	NA	NA	NA	NA
WP_151070212.1\|1775379_1776027_+	LemA family protein	NA	NA	NA	NA
WP_151070213.1\|1776023_1776875_+	YgcG family protein	NA	NA	NA	NA
WP_151070214.1\|1776874_1777375_+	hypothetical protein	NA	NA	NA	NA
WP_151070215.1\|1777415_1778693_+	DUF4010 domain-containing protein	NA	NA	NA	NA
WP_151070216.1\|1778960_1779308_+	YHYH domain-containing protein	NA	NA	NA	NA
WP_151070218.1\|1780578_1780824_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_151070219.1\|1781259_1781616_+	hypothetical protein	NA	NA	NA	NA
WP_151070220.1\|1782767_1784096_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_151070221.1\|1784264_1785713_+	hypothetical protein	NA	NA	NA	NA
WP_151070222.1\|1785721_1786495_+	hypothetical protein	NA	NA	NA	NA
WP_151070223.1\|1786497_1787943_+	hypothetical protein	NA	NA	NA	NA
WP_151070224.1\|1787939_1788680_+	hypothetical protein	NA	NA	NA	NA
WP_151070225.1\|1788818_1789565_+	DNA/RNA non-specific endonuclease	H6X497	Enterobacteria_phage	2.5e-22	32.5
WP_151070226.1\|1789734_1794339_+	very short patch repair endonuclease	NA	NA	NA	NA
WP_151070227.1\|1794618_1795803_+	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_167525631.1\|1796248_1797103_+	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_151070894.1\|1797447_1797738_+	YHYH domain-containing protein	NA	NA	NA	NA
WP_151070229.1\|1797984_1798449_+	hypothetical protein	NA	NA	NA	NA
WP_151070230.1\|1798747_1799056_+	H-NS histone family protein	NA	NA	NA	NA
WP_151070231.1\|1799553_1800066_-	hypothetical protein	NA	NA	NA	NA
WP_151070232.1\|1800271_1800847_+	hypothetical protein	NA	NA	NA	NA
WP_151070191.1\|1800992_1802537_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	2.5e-157	55.9
WP_151070192.1\|1802564_1803302_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.4e-71	56.6
WP_167525632.1\|1803517_1804033_+	hypothetical protein	NA	NA	NA	NA
WP_151070233.1\|1805059_1806331_+	hypothetical protein	NA	NA	NA	NA
WP_151070234.1\|1806891_1807380_-	hypothetical protein	NA	NA	NA	NA
WP_151070235.1\|1807613_1809164_+	hypothetical protein	NA	NA	NA	NA
WP_151070236.1\|1809160_1809967_+	hypothetical protein	NA	NA	NA	NA
WP_151070237.1\|1810197_1812270_+	hypothetical protein	NA	NA	NA	NA
WP_063237702.1\|1812872_1813808_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_151070238.1\|1813941_1815741_+	DNA alkylation response protein	NA	NA	NA	NA
WP_151070239.1\|1815960_1816935_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_151070240.1\|1816952_1818074_+	CoA transferase	NA	NA	NA	NA
WP_063237706.1\|1818178_1819879_-	lactate permease LctP family transporter	NA	NA	NA	NA
WP_151070241.1\|1820123_1821569_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_151070242.1\|1821565_1822303_-	LUD domain-containing protein	NA	NA	NA	NA
WP_151070243.1\|1822299_1823082_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_063237789.1\|1823266_1823938_+	FCD domain-containing protein	NA	NA	NA	NA
WP_151070244.1\|1823988_1825026_-	hypothetical protein	NA	NA	NA	NA
WP_151070245.1\|1825551_1825959_-	hypothetical protein	NA	NA	NA	NA
WP_167525633.1\|1825945_1826086_-	hypothetical protein	NA	NA	NA	NA
WP_151070246.1\|1826126_1827185_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_151070247.1\|1827192_1828227_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_151070248.1\|1828229_1830110_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_151070249.1\|1830125_1830665_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP032519

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP032519_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP032519_1

1461361-1461468

Orphan

Consensus_repeat	Method
TCAACGGCCAACAGCATGTCACCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP032519_1

>merge|NZ_CP032519|1|1461361-1461468|CRISPRCasFinder
TCAACGGCCGACAGCATGTCACCAACCGCGACACCAACGCATCAACGGCCAACAGCATGTCACCAACCGCGACACCAACGCATCAACGGCCAACAGCATGTCACCAAC

>NZ_CP032519|1|1|1461361-1461468|CRISPRCasFinder
TCAACGGCCGACAGCATGTCACCAAC	CGCGACACCAACGCATCAACGGCCAACAGCATGTCACCAACCGCGACACCAACGCA
TCAACGGCCAACAGCATGTCACCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP032519.1\|WP_063242139.1\|1455123_1456437_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226645
NZ_CP032519.1\|WP_063241865.1\|1471496_1472432_+\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223698
NZ_CP032519.1\|WP_063242135.1\|1448228_1448693_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP032519.1\|WP_063241869.1\|1468032_1468815_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181295
NZ_CP032519.1\|WP_063242134.1\|1447649_1448189_-\|septation-protein-A	unknown	unknown	gnl\|CDD\|234704
NZ_CP032519.1\|WP_063241870.1\|1466127_1467990_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173842
NZ_CP032519.1\|WP_063242140.1\|1456433_1457207_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213186
NZ_CP032519.1\|WP_063241867.1\|1469468_1470479_+\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176190
NZ_CP032519.1\|WP_063241864.1\|1472500_1473403_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180458
NZ_CP032519.1\|WP_063242141.1\|1457206_1457920_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213191
NZ_CP032519.1\|WP_063242137.1\|1452621_1453872_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380552
NZ_CP032519.1\|WP_151071582.1\|1450854_1452480_+\|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl\|CDD\|235908
NZ_CP032519.1\|WP_063241866.1\|1470584_1471439_+\|class-II-aldolase/adducin-family-protein	unknown	unknown	gnl\|CDD\|235743
NZ_CP032519.1\|WP_151072829.1\|1448828_1450373_-\|YdiU-family-protein	unknown	unknown	gnl\|CDD\|234583
NZ_CP032519.1\|WP_063242138.1\|1454171_1455119_+\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223633
NZ_CP032519.1\|WP_063241872.1\|1464001_1464640_+\|bifunctional-nicotinamidase/pyrazinamidase	unknown	unknown	gnl\|CDD\|238493
NZ_CP032519.1\|WP_167525731.1\|1458342_1460493_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227115
NZ_CP032519.1\|WP_151071583.1\|1461889_1463971_+\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236864
NZ_CP032519.1\|WP_063241871.1\|1464699_1465878_+\|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl\|CDD\|180843
NZ_CP032519.1\|WP_063241868.1\|1468932_1469370_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527

Protein	Function_ID	Function_description	E-value
NZ_CP032519.1\|WP_063242139.1\|1455123_1456437_+\|ABC-transporter-permease	gnl\|CDD\|226645	COG4177, LivM, ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism].	3.20185e-54
NZ_CP032519.1\|WP_063241865.1\|1471496_1472432_+\|glutathione-S-transferase-family-protein	gnl\|CDD\|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	2.41106e-17
NZ_CP032519.1\|WP_063242135.1\|1448228_1448693_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	3.74306e-91
NZ_CP032519.1\|WP_063241869.1\|1468032_1468815_+\|SDR-family-oxidoreductase	gnl\|CDD\|181295	PRK08213, PRK08213, gluconate 5-dehydrogenase; Provisional.	3.70266e-174
NZ_CP032519.1\|WP_063242134.1\|1447649_1448189_-\|septation-protein-A	gnl\|CDD\|234704	PRK00259, PRK00259, intracellular septation protein A; Reviewed.	2.69688e-96
NZ_CP032519.1\|WP_063241870.1\|1466127_1467990_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	0
NZ_CP032519.1\|WP_063242140.1\|1456433_1457207_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	8.26821e-110
NZ_CP032519.1\|WP_063241867.1\|1469468_1470479_+\|NADP-dependent-oxidoreductase	gnl\|CDD\|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	1.89799e-180
NZ_CP032519.1\|WP_063241864.1\|1472500_1473403_+\|SDR-family-oxidoreductase	gnl\|CDD\|180458	PRK06194, PRK06194, hypothetical protein; Provisional.	0
NZ_CP032519.1\|WP_063242141.1\|1457206_1457920_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	1.71436e-110
NZ_CP032519.1\|WP_063242137.1\|1452621_1453872_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380552	cd06329, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs). Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.	1.35994e-166
NZ_CP032519.1\|WP_151071582.1\|1450854_1452480_+\|long-chain-fatty-acid--CoA-ligase	gnl\|CDD\|235908	PRK07008, PRK07008, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP032519.1\|WP_063241866.1\|1470584_1471439_+\|class-II-aldolase/adducin-family-protein	gnl\|CDD\|235743	PRK06208, PRK06208, class II aldolase/adducin family protein.	6.69747e-175
NZ_CP032519.1\|WP_151072829.1\|1448828_1450373_-\|YdiU-family-protein	gnl\|CDD\|234583	PRK00029, PRK00029, YdiU family protein.	0
NZ_CP032519.1\|WP_063242138.1\|1454171_1455119_+\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|223633	COG0559, LivH, Branched-chain amino acid ABC-type transport system, permease components [Amino acid transport and metabolism].	3.58782e-60
NZ_CP032519.1\|WP_063241872.1\|1464001_1464640_+\|bifunctional-nicotinamidase/pyrazinamidase	gnl\|CDD\|238493	cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is also called pyrazinamidase, because in converts the tuberculosis drug pyrazinamide (PZA) into its active form pyrazinoic acid (POA).	3.19458e-98
NZ_CP032519.1\|WP_167525731.1\|1458342_1460493_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227115	COG4774, Fiu, Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism].	0
NZ_CP032519.1\|WP_151071583.1\|1461889_1463971_+\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	1.33205e-142
NZ_CP032519.1\|WP_063241871.1\|1464699_1465878_+\|acetyl-CoA-C-acyltransferase	gnl\|CDD\|180843	PRK07108, PRK07108, acetyl-CoA C-acyltransferase.	0
NZ_CP032519.1\|WP_063241868.1\|1468932_1469370_+\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.5536e-33

>NZ_CP032519.1|WP_167525731.1|1458342_1460493_+|TonB-dependent-siderophore-receptor
MQGASAQESQPAAAPTGQAAPVTLERVTVTGKREDGYKVEEAQSPKFTAPLLDTPKSVTVVPAEVIQQSGSNSLQDALRTTPGITFGAGEGGNPIGDRPFIRGFDSMSSIYVDGVRDTASQTRDTFNIENIEVIKGPSSAFGGKGSAGGMINIVSKLPQAENFAQGSIGVGTDSYFRATADGNYVINDNTAVRLNALGYTANVPGRDEVDQNSWGFAPSVTFGMKSDTKVTLSYYHLQGNGMPDYSIPYARPFRQAIKDNPTQPADVDRNNFYGLTDRDFQKTQSDIATATVKHDFRNGLVFSNTTRWGRSTNNYIVTNPDDSRGNVPNGFVWRNTKSRDSATETLTNQTDLTAEFHTGRFKHNALFGFEFSRDDTTNTPYVVSTGNGDCTPALVASFNCTSLFNPNPNDPWQGSITKSPNRQETKTNTRSVYLFDTMEITKQWMVNGGIRYDSYRTTSSTPATNTFISNDSNFFNYQAGVVYKPVEYGSIYVSYGTASTPPGSTNGDGADNISLAQRDLEPETARSVEIGTKWDLLAKRLSLTGAIFQIEKNNARVAVDNNTTINAGKQRVKGFELGFAGNLTDKWGVFGGYTYLNSELIDNGPQAANAANNGNQFPNTPKNSFSLWTTYQVLPALTVGGGAYYVDKVYANPANSAFVPSYWRFDLMAAYRVNKNLSLQLNVQNLFDKTYYTKAHNHYGALGAGRFGMLTANFKF
>NZ_CP032519.1|WP_063242141.1|1457206_1457920_+|ABC-transporter-ATP-binding-protein
MGKRMLEVTGLHAYYGKSHILHGVDAHIGEGEIVALLGRNGVGRSTMAKAILGMVKAEGSVKFRGEEILGRRTFEIAHLGIGYVPENRDIFPTLTVRQNLLLGEKRNPRQPRPRWSVEDMFNMFPRLRERENTAAGVLSGGEQQMLTLCRTLMGDPDLVLIDEPTEGLAPMIVALVGDYLKTLKERGVSVLLIEQKLAIALDISQRVYVMGHGHIVFEGTPGELKANSQIRKEWLEV
>NZ_CP032519.1|WP_063242140.1|1456433_1457207_+|ABC-transporter-ATP-binding-protein
MTAALELTEVRKKFGQTEIIRGVNLSIPKGERHALIGPNGAGKSTTFNLISGRFAPTSGTVRLNGQEIGGLQPFVINRMGLSRSFQITNIFHRLSVFENLRCAVLWSLGYKYSFWHRLTGLRDARERADEVLELIGMQHRRNTQAGLLTYAEQRALEIGITIAGGAEVILLDEPTAGMSRSESDHAVELIRKVTVGKTLVMVEHDMSVVFGLADRISVLVYGEVIATDTPQAIRSNRKVKEAYLGTTLDEDTTEGVH
>NZ_CP032519.1|WP_063242139.1|1455123_1456437_+|ABC-transporter-permease
MEQAMQQPRGPAATGRTLRYRPLNLARWVIWSLTILTMLVLPLVFTGGFAITLMSQMGIMIIFALSYNMLLGQTGMLSFGHAVYSGLGAFIAVHVLNMVGAGTAWLPVSMLPLVGGLAGAFFGVIFGYVTTKKAGTTFAMITMGIGEMVFASSLMFPEFFGGEGGISTNRVVGDPFLGITFGPGRQVYYLIAVWCLVSMVAMYAWTQTPLGRIANAVRDNPERVEFIGYNTQRVRYLVLVLSAFFAGISGALAAINFEIVSAENVSAVRSGGVLLAVFIGGAGVFFGPIIGAVVFMLFAVALSDLTKAWLLYLGLFFVLMVMFVPGGLASLLLMQLPLAAKGKLRRMLPSYAKAGAAGVVLLLAMIVTVELVYKVQVDSANGTAMKLFGVGFDAATWAPWLVAAVLWAVGLAAWRLTVRASRAEWDKVQAEIAGGTA
>NZ_CP032519.1|WP_063242138.1|1454171_1455119_+|branched-chain-amino-acid-ABC-transporter-permease
MEFFVISLLNGISYGLLLFMLSSGLTLIFSMMGVLNFAHASFYMLGAYFAYTIASKVGFWPALIFAPLLVAGAGALVERFGLRTVHKYGHVAELLFTFGLAYLIEEGVKLVWGLAAVPYRIPAELEGPLFQVFTSTFPKYRAFMMLVSLGMLVAIYLVLTRTRIGLVIQAALTHPEMVEALGHNVPRVFMMVFGGGAALAGLAGVIGGNAFVTEPSMAAAVGSIVFVVAVVGGMGSLVGAFIASILIGVLQTFAVTIDASLAGLLRSLGMAVGEATPFYALWKLTVAQVAPVLPYLLLVVMLIFRPRGLMGTRES
>NZ_CP032519.1|WP_063242137.1|1452621_1453872_+|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MTKMRPLVAGVAMFAAMGSALVSGSALADTVKIAFIDPLSGLMAPVGQNQLKSWQYVADVANQKGWAGAHKFEVVGFDNKLSPQESLTILKQAIDQNIRYIVQGNGSSVGLALQDAVAKHNERNPGKEIIYLNYAAVDPDMTNAKCNYWHFRLDANSDMKMEALTTFLAKDPNVKKVYLINQNYSFGHQVAKAAKDYLKRKRPDIQIVGEDLHPLAQVKDFAPYAAKIKASGADTVITGNWGSDLALLIKAGKDAGLATNYYTYYAGTTGVPTAMGAAGAEHVKYVGYYNPNNKGFKGADVIEGFKKKYNDDFYVMASYTGIAMLSKAFKDANSTDPVKVAKALEGIKVESMNGLVEMRNTDHQAQQPLVVATWTKIDGKDIKYDQENTGYGWKTNAQMDQYVSAQPTSCQMKRPG
>NZ_CP032519.1|WP_151071582.1|1450854_1452480_+|long-chain-fatty-acid--CoA-ligase
MALMGQMMSAPLLISSIIKHAARYYGSTEIVSRRTEGDLHRYTYRDCELRARKVAQALGALGVQQGERVGTLAWNGYRHLEVYYGVSGMGAVCHTINPRLFPEQIAYIVNHAEDSYVFFDLTFLPLVEGVAPHCPNVKGWVAMTDRAHMPAESKVPLLCYEELVEAQDGNYEWPQFDEHLASSLCYTSGTTGNPKGALYSHRSTVLHSYASALPDALGCSARDVILPVVPMFHVNAWGLPYSVPLVGAKLVLPGAKLDGASLYELFEQEKVTFSAGVPTVWLGLLQYVQSNKLKFSTFRRTVIGGSAAPPAMIRALEALDVDVIHAWGMTEMSPLGTSCKLLARHEELSDAERHKIQEKQGRVIFGVDMKIVDGEGKELPWDGKAFGDLMVRGPWIIDQYYRNGNNPLVDGWFPTGDVATIDEDGFMQITDRSKDVIKSGGEWISSIDIENVAAAHPAVHMAACISAYHPKWDERPLLVVVKKPGAEVTREELLQFFEGKVAKWWIPDDVAFVTEIPLTATGKMQKLRLREQFKDYKLPAA
>NZ_CP032519.1|WP_151072829.1|1448828_1450373_-|YdiU-family-protein
MHDSDTSGAAALAVPFTTTPGFSTLGEKFFTRLQPTPLPSPYLVGVAPAAAALLGWDAGVGAEPGFVETFVGNQVPHWADPIATVYSGHQFGIWAGQLGDGRAIRLAQADTATGPWEIQLKGAGLTPYSRMADGRAVLRSSIREYLCSEAMAALGVPTTRALSIVGSDAPVRRETIETSAVVTRLAPTFVRFGHFEHFAAHDDVASLRQLADFVIDNFMPALRDEARPYQALLREVSLRTADLVAHWQAIGFCHGVMNTDNMSILGLTIDYGPFGFLDAFDANHICNHSDTQGRYAYSQQPQVAFWNLHCLAQALLPLWLPAEDAGKEGARDAAIEAARAAIDPFRDRYAAAFFRHYRAKLGLRPPAGGDDKVDEPLLTSLFQLLHGQRVDYTLFWRKLCGISSQDASRDAPVRDLFLDRAAFDAWATDYRARLRAEQSDDAARELEMLAVNPKYVLRNHLAETAIRHAREKDFSETGRLLAVLSRPFDEQPEAEHYAALPPDWAAGLEVSCSS
>NZ_CP032519.1|WP_063242135.1|1448228_1448693_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTTTKTDAEWRDQLSDIEYRVTREAATERPFTGRYWDHWERGIYNCVGCGTPLFESATKFDAGCGWPSYFRPINGEVIAEHADHTHGMVRVEVRCKECGSHLGHVFEDGPAPTGLRYCINSAALKFDDRDPAQREADHAHDAGSGNEPRRDPQR
>NZ_CP032519.1|WP_063242134.1|1447649_1448189_-|septation-protein-A
MKFLFDLFPVILFFAAFKLADIYTATAVAIAATVVQIGWVWFRHRKVEPMQWVSLLIIAVFGGATLVLHNETFIKWKPTVLYWMFAVALLGSVMVWRKNLIRAMMEKQVTLPDPVWTRLNAAWAGFFAAMGVLNLYVAYQFSTDVWVNFKLFGSMGLMLVFIVAQSVWLSRHMPENSQD
>NZ_CP032519.1|WP_151071583.1|1461889_1463971_+|3-hydroxyacyl-CoA-dehydrogenase
MTAQYQVQDGVAVITLDNPPVNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAGKAFSGGADIREFNTPKAMQEPTLHSVIRVLEASSKPVVAAVHSVAMGGGLELALGCNYRVASKGAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIVEGDVLPAAVKFAQNVGAASGPHPKVRDLKVRHENPEGYLGFARNTVAAMAKNFPAPLKCLEAVAGSLKPFEQGLKEEREGFLFLVTTPESRALRHAFFGERAASKIPDVPEGIPVRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGIIRKNYENSAKKGKLTQEKVEQRMGLLSTTLSYDDIKDADMVIEAVFEEMGVKEIVFKKLDEVMKQGAILASNTSTLDVNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEKTGKDVLATVMQIGKKIKKTAVVSGVCDGFIGNRMIEQYSRQAGYLLDEGALPEQVDKAIEKFGFAMGPFRMGDLAGNDIGWAIRKRRAVDKPDIQYSKTADLLCEMGRYGQKTGAGWYDYKAGDRKPYPNQQVNDMIVQHSKDLGLTRRKISDEEIVERLVLALVNEGAKILEEGIASKASDIDMVYLTGYGFPLFRGGPMLYADQVGLYNVALAMKKYAKGYHGEAWQVAPLLQKLADEGKGFNG
>NZ_CP032519.1|WP_063241872.1|1464001_1464640_+|bifunctional-nicotinamidase/pyrazinamidase
MNTIIGPDDCLLVIDVQNDFMPGGALAVPNGDEVVPVINRLARAFGHVVVTQDWHPAAHVSFAANHAGTQPFQMLTLPYGEQVLWPVHCVQDTPGAALHAGLHVPHARLVIRKGHHADVDSYSAFLEADRTTRTGLAGYLREHGVRRVFCAGLATDYCVAWSALDARAAGFEAAVIEDACRAIDLQGSLARAWQDLGAAGVARVMSADVLNG
>NZ_CP032519.1|WP_063241871.1|1464699_1465878_+|acetyl-CoA-C-acyltransferase
MNEAVIVSTARTGLAKSWKGAFNMTHGATLGGHAVQHAIARAKIDAAEVEDVLMGCANPEGATGANIARQIALRAGCPVTVPGATVNRFCSSGLQTIAMAAQRVIADEGDIFVAGGVESISCVQQEMNRHMIQESWLVKNKPEIYWNMLQTAENVAKRYNISKDRQDEYGVRSQQRAAAAQEAGKFKDEIVPITVLAGVADKSTGQLVTKEVTLDRDEGIRADTTLEGVAKIRSAVPGGVITAGNASQFSDGASAAVVMNARVAEAKGLQPLGVFRGFAVAGCEPDEMGIGPVFAVPKLLKKAGLKVDDIGLWELNEAFAVQVLYCADKLGIPMDRLNVNGGAIAVGHPYGVSGARLVGHALIEGKRRGVKYVVVTMCIGGGQGAAGLFEVL
>NZ_CP032519.1|WP_063241870.1|1466127_1467990_+|acyl-CoA-dehydrogenase
MSMILSRRDLNFILYEWLKVDELTRIPRYADHSRETFDAALDTCEKIATDLFAPHNKKNDQHEPEFDGETVSIIPEVSTALKAFCEAGLMAAGQDYELGGMQLPVVVEKAGFAYFKGANVGTSSYPFLTIGNANLLLAHGTPAQVETFVKPEMEGRFFGTMCLSEPQAGSSLSDITTRAEYEGESPLGAQYRLRGNKMWISAGEHELSDNIVHLVLAKIPGPDGKLIPGVKGISLFIVPKYLVNDDGSLGEHNDVVLAGLNHKMGYRGTTNCLLNFGEGMKYKPGGRAGAIGYLVGEPHKGLACMFHMMNEARIGVGLGAVMLGYTGYLHALDYARNRPQGRPVGPGGKDAASPQVKLVEHADIRRMLLAQKSYVEGGLALNLYCARLVDEEEAAAAAGDQEAHARLALLLDILTPIAKSWPSQWCLEANNLAIQVHGGYGYTREYNVEQFYRDNRLNPIHEGTHGIQGLDLLGRKVVMKDGAAFRLLGERVQAAIGRALAADDAELAQQARALGAATKRLADVTQTLWSAGDSNVTLANASVYLEAFGHVVVAWIWLEQALLAQAALAQASGKEDQDFYRGKLAAAAYFFRFELPRVGPQLDLLASLDRTTLDMQDAWF
>NZ_CP032519.1|WP_063241869.1|1468032_1468815_+|SDR-family-oxidoreductase
MRTIQQLFDLKGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELRAAQEHLKGLGIEADWIAADGSQESEIARLADEAIARLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLSQRIGKLSMIPRRYGRIINVASIAGLAGNPPGSMDTIAYNTSKGAVVNFTRTLAGEWGEHNITVNALAPGFFPSKMTKGSLERMGVEAMCAGVPLHRLGDDEDLKGAALLFASDAGKHITGQILAVDGGVSAV
>NZ_CP032519.1|WP_063241868.1|1468932_1469370_+|PaaI-family-thioesterase
MNQYTGSLSHIPFLADLGVTCTVAEGGRSELSLPIEKRHQNSWDMAHGGVIMTLLDVAMAVAGRSSDADGRGVVTIEMKSSFMAPGRGHLTARGTTVHRTTTMVFCEAEIVDADGKTVARGSGTFKYIRRMPPQRPGETDTGADG
>NZ_CP032519.1|WP_063241867.1|1469468_1470479_+|NADP-dependent-oxidoreductase
MSNTFKRIVLASRPEGAVTPANFRLEDVPVPQIADGQVLVRNHYLSLDPYMRGRMNDSKSYAAPQPLNEVMIGGTVGEVVESKNSKFKPGDKVVGMFGWQEMGVSDGTGLQPVDTTHIPLSAYLGSVGMPGVTAWYGLNKIIQPKAGQTIAVSAASGAVGSVVGQLAKLAGCRAVGFAGGKDKCDYVVNELGFDACIDYKAAKDPKELYTMLKEATPDGIDGYFENVGGEIFDAVLSRMNAFGRIALCGMIAGYDGNPLPLKNPQLILISRLTIEGFIVSEHMEVWPQALKELGTAVAQGKLKFRESIAEGLASAPEAFMGLLKGKNFGKQLVKLV
>NZ_CP032519.1|WP_063241866.1|1470584_1471439_+|class-II-aldolase/adducin-family-protein
MNAPQVPQVQQATDDDIGAGLPEEVRARYRNLPRPPQFATVGEERLHRKQRLAAAFRLFSKFGFDEGVAGHITARDPEFPDTFWVNPFGVHFSQVRVSNLIRCDHHGDVVEGDYPVNAAAFAIHSRVHQTRPDAVAAAHSHSTYGRAWSTLGRPLDALTQDVCAFYNDHAVYDDFGGVVVELDEGQRIANALGQNKAAILQNHGLLTVGKTVDEAAWWFITMERSCQVQLLAEAAAARTQAPLKVIADAAARQAYSIVGTAQAGWFQFQPLYARIVKEQPDLLD
>NZ_CP032519.1|WP_063241865.1|1471496_1472432_+|glutathione-S-transferase-family-protein
MADIILHQYATSPFSEKVRLLLGAKGLAWQAVEIPAILPKPDLLALTGGYRRTPVMQVGADIYCDTALICEVIDTLAPSPPLYPPAQAAVARVMAAWFDSALFTAAATYVFQPDGVASMLGHLSPAQVQAFVADRKAMRGDTNALRMPPPEATAQLHETFGRLETQFAAGVEHVAGPLLSVADFSLYHNLWFIRRAGALAQMLEAYPRLQAWYARMNTFGHGRPRVVGGEQAIGVALSADPVALDEGVREGEGLQPGDAVTITPTDYARDPVAGVLLALGPHRVTLRRQDPRAGALNVHFPRQGYQVRRAA
>NZ_CP032519.1|WP_063241864.1|1472500_1473403_+|SDR-family-oxidoreductase
MKDFSNKVAVITGGASGFGKEFARIGADLGMKLVLADVQEDALDATVAEFKARNVPVIGLRTDVSRAEQVQALADAAMEAFGQVNLLFNNAGVGAGGLLWENSLQDWEWVLGVNLYGVIHGVRIFTPLMLAAAEKDPSYQGHIVNTASMAGLLNPPAMGVYNVSKHAVVSLSETLYQDLGLVTGQVRCSVLCPYFVPTGISQSQRNRPAELANQTPPTRSQLVSQALSDKAVGSGKVTAAEVAHKTFDAIRADSFYIYSHPQALEPVRQRFEDIVGPRNPGDPFADKPEVRAGLVAALRG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

823874 : 832774

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063237080.1\|823874_825290_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-70	36.5
WP_063237081.1\|825370_826315_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	4.2e-14	26.8
WP_063237082.1\|826342_827338_+	ADP-glyceromanno-heptose 6-epimerase	Q58M42	Prochlorococcus_phage	1.2e-27	33.4
WP_063237083.1\|827507_827885_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_063237085.1\|828138_829440_+	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	2.2e-146	65.5
WP_063237086.1\|829569_830472_+	cysteine synthase CysM	C3U2M1	Lactococcus_phage	1.8e-51	42.1
WP_151071313.1\|830541_831648_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_151071314.1\|831850_832774_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	1.1e-43	36.5

DBSCAN-SWA_2

2416649 : 2460030

Burkholderia_phage(20.0%)

head,protease,tail,portal,terminase,integrase,capsid

attL 2417190:2417232|attR 2460095:2460137

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063238267.1\|2416649_2417021_+	hypothetical protein	J9RWD8	Pseudomonas_phage	1.1e-31	64.7
2417190:2417232	attL	NA	NA	NA	NA
WP_151072159.1\|2417570_2417984_-	hypothetical protein	NA	NA	NA	NA
WP_167525708.1\|2417965_2418151_-	hypothetical protein	NA	NA	NA	NA
WP_151072160.1\|2418147_2418561_-	hypothetical protein	NA	NA	NA	NA
WP_151072161.1\|2418544_2418883_-	chemotaxis protein	NA	NA	NA	NA
WP_151072162.1\|2418918_2419449_-	hypothetical protein	A0A0H5BBZ5	Pseudomonas_phage	1.9e-40	56.0
WP_151072163.1\|2419986_2420244_-	hypothetical protein	I6NSG3	Burkholderia_phage	1.7e-10	42.6
WP_151072164.1\|2420322_2420616_-	hypothetical protein	A0A0M4RBJ6	Mycobacterium_phage	7.8e-12	41.5
WP_151072165.1\|2420612_2422319_-	hypothetical protein	NA	NA	NA	NA
WP_151072166.1\|2422340_2422733_-	hypothetical protein	Q6VSZ7	Vibrio_phage	2.0e-10	38.8
WP_151072167.1\|2422794_2423397_-\|tail	tail fiber assembly protein	K4NXJ9	Burkholderia_phage	2.5e-20	34.5
WP_151072168.1\|2423408_2424074_-\|tail	phage tail protein	A0A1W6JT73	Escherichia_phage	1.2e-28	52.1
WP_167525709.1\|2424089_2427281_-	hypothetical protein	A0A1B1IRL4	uncultured_Mediterranean_phage	1.2e-73	29.0
WP_167525710.1\|2427291_2427693_-	hypothetical protein	NA	NA	NA	NA
WP_151072170.1\|2427692_2428244_-	hypothetical protein	A0A2P1CL89	Pantoea_phage	5.8e-16	28.2
WP_151072171.1\|2428243_2428834_-	hypothetical protein	A0A0E3GML3	Enterobacteria_phage	1.9e-25	38.5
WP_151072172.1\|2428837_2431597_-\|tail	phage tail tape measure protein	A0A2H4J107	uncultured_Caudovirales_phage	4.7e-82	33.0
WP_151072173.1\|2431586_2432030_-	hypothetical protein	A0A0S2SXK7	Bacillus_phage	3.0e-07	33.3
WP_151072174.1\|2432029_2432275_-	hypothetical protein	NA	NA	NA	NA
WP_151072175.1\|2432725_2433370_-\|tail	phage tail protein	NA	NA	NA	NA
WP_151072176.1\|2433430_2433778_-	DUF3168 domain-containing protein	C4ML11	Xanthomonas_virus	8.1e-08	35.7
WP_151072177.1\|2433770_2434109_-\|head	phage head closure protein	NA	NA	NA	NA
WP_151072178.1\|2434105_2434432_-\|head,tail	phage gp6-like head-tail connector protein	Q3HQT2	Burkholderia_phage	1.2e-16	41.6
WP_151072179.1\|2434433_2434691_-	hypothetical protein	NA	NA	NA	NA
WP_151072873.1\|2434751_2435966_-\|capsid	phage major capsid protein	I7HDH9	Xanthomonas_virus	1.9e-128	66.4
WP_151072180.1\|2436085_2436955_-\|protease	Clp protease ClpP	K7PH05	Enterobacteria_phage	1.2e-76	61.8
WP_151072181.1\|2436951_2438253_-\|portal	phage portal protein	G0ZT36	Aeromonas_phage	1.1e-174	73.9
WP_151072182.1\|2438252_2439938_-\|terminase	terminase large subunit	S4TSQ6	Salmonella_phage	2.8e-231	71.2
WP_151072183.1\|2439942_2440446_-\|terminase	terminase small subunit	Q3HQS6	Burkholderia_phage	9.3e-21	47.9
WP_151072184.1\|2440961_2441192_-	hypothetical protein	NA	NA	NA	NA
WP_151072185.1\|2441204_2441411_-	HNH endonuclease	NA	NA	NA	NA
WP_151072186.1\|2441998_2442652_-	hypothetical protein	NA	NA	NA	NA
WP_151072188.1\|2442929_2443493_-	hypothetical protein	NA	NA	NA	NA
WP_151072189.1\|2443680_2444025_-	hypothetical protein	NA	NA	NA	NA
WP_151072190.1\|2444021_2444414_-	DUF1064 domain-containing protein	A0A0R6PIZ9	Moraxella_phage	7.2e-13	42.0
WP_151072191.1\|2444584_2444800_-	hypothetical protein	NA	NA	NA	NA
WP_151072192.1\|2444796_2445840_-	helix-turn-helix domain-containing protein	A4JX55	Burkholderia_virus	1.9e-44	39.8
WP_151072193.1\|2446339_2446633_-	DUF1364 family protein	NA	NA	NA	NA
WP_151072194.1\|2446632_2446926_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167525711.1\|2446934_2447111_-	hypothetical protein	NA	NA	NA	NA
WP_151072195.1\|2447107_2447299_-	hypothetical protein	NA	NA	NA	NA
WP_151072196.1\|2447295_2447598_-	DNA-binding protein	NA	NA	NA	NA
WP_151072197.1\|2447755_2447965_+	hypothetical protein	NA	NA	NA	NA
WP_151072198.1\|2448057_2448312_-	hypothetical protein	NA	NA	NA	NA
WP_151072874.1\|2448308_2448572_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_151072199.1\|2448705_2449404_+	XRE family transcriptional regulator	Q94MM0	Bordetella_phage	5.4e-35	50.0
WP_151072200.1\|2449423_2449954_+	hypothetical protein	NA	NA	NA	NA
WP_151072201.1\|2449987_2450377_+	hypothetical protein	NA	NA	NA	NA
WP_151072202.1\|2450369_2450945_+	hypothetical protein	NA	NA	NA	NA
WP_151072203.1\|2450996_2451194_-	hypothetical protein	NA	NA	NA	NA
WP_151072204.1\|2451392_2451665_+	hypothetical protein	NA	NA	NA	NA
WP_151072205.1\|2451661_2451895_+	hypothetical protein	R4JG80	Burkholderia_phage	6.6e-06	57.7
WP_151072875.1\|2452503_2453157_+	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_151072876.1\|2453255_2453621_+	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_151072877.1\|2453803_2454169_+	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_151072206.1\|2454189_2454543_+	four helix bundle protein	NA	NA	NA	NA
WP_151072207.1\|2454763_2455951_+	RNA-directed DNA polymerase	A0A0N7AE80	Bacillus_phage	5.0e-49	34.5
WP_151072208.1\|2457093_2457300_+	hypothetical protein	NA	NA	NA	NA
WP_151072209.1\|2457299_2457587_+	DUF4031 domain-containing protein	A0A125RNQ7	Pseudomonas_phage	3.7e-22	61.1
WP_151072210.1\|2457589_2458273_+	HNH endonuclease	NA	NA	NA	NA
WP_151072211.1\|2458269_2458548_+	hypothetical protein	NA	NA	NA	NA
WP_151072878.1\|2458696_2458909_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_151072879.1\|2459079_2460030_+\|integrase	integrase	NA	NA	NA	NA
2460095:2460137	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3018716 : 3028000

Methanothermobacter_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063240196.1\|3018716_3019919_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.4e-37	30.6
WP_063240197.1\|3019949_3020450_+	dUTP diphosphatase	A0A289ZTC1	Serratia_phage	7.3e-42	54.9
WP_063240256.1\|3020506_3021355_-	VOC family protein	NA	NA	NA	NA
WP_151072470.1\|3021402_3022401_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_029045978.1\|3022561_3024856_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	3.1e-172	43.5
WP_010814998.1\|3024852_3025179_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.3e-12	46.9
WP_063240199.1\|3025710_3025917_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.9e-20	75.8
WP_063240200.1\|3026140_3026602_-	glyoxalase	NA	NA	NA	NA
WP_063240201.1\|3026749_3028000_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.1e-11	64.8

DBSCAN-SWA_4

3051274 : 3061756

Roseobacter_phage(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063240223.1\|3051274_3052804_+	polynucleotide adenylyltransferase PcnB	A0A1B0V011	Roseobacter_phage	3.9e-22	32.3
WP_063240224.1\|3052804_3053332_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_151072482.1\|3053363_3054005_+	deoxynucleoside kinase	A0A1J0F9Q3	Only_Syngen_Nebraska_virus	1.7e-06	28.2
WP_151072483.1\|3054111_3054933_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0P0BXC9	Ostreococcus_lucimarinus_virus	6.3e-35	31.7
WP_063240227.1\|3054937_3055636_+	ABC transporter permease	NA	NA	NA	NA
WP_151072484.1\|3055632_3056316_+	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	6.9e-11	29.3
WP_151072485.1\|3056338_3058261_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	A0A0B5J984	Pandoravirus	7.6e-47	36.5
WP_063240230.1\|3058489_3059635_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	1.7e-22	36.8
WP_151072486.1\|3059806_3061756_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.8e-145	50.3

DBSCAN-SWA_5

3389384 : 3459064

Ralstonia_phage(16.67%)

integrase,protease,capsid,transposase

attL 3389158:3389205|attR 3458448:3458495

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3389158:3389205	attL	NA	NA	NA	NA
WP_151072610.1\|3389384_3390749_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A221SAN4	Ralstonia_phage	3.8e-08	22.4
WP_151072611.1\|3390700_3390919_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_151072612.1\|3391216_3391510_-	hypothetical protein	A0A1B0UY37	Roseobacter_phage	2.2e-14	43.9
WP_151072613.1\|3391527_3394212_-	type III restriction endonuclease subunit R	NA	NA	NA	NA
WP_151072614.1\|3394208_3396224_-	hypothetical protein	NA	NA	NA	NA
WP_151072615.1\|3396220_3397537_-	hypothetical protein	NA	NA	NA	NA
WP_151072904.1\|3397801_3398629_-	NAD-dependent deacetylase	NA	NA	NA	NA
WP_151072616.1\|3398943_3400575_-	ATP-binding domain-containing protein	NA	NA	NA	NA
WP_151072617.1\|3400691_3401627_-	5'-nucleotidase	NA	NA	NA	NA
WP_151072618.1\|3401635_3405016_-	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_151072619.1\|3405012_3407676_-	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_151072620.1\|3407909_3408671_+	hypothetical protein	NA	NA	NA	NA
WP_151072621.1\|3408677_3409745_-	WYL domain-containing protein	NA	NA	NA	NA
WP_167525721.1\|3409999_3411415_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_167525722.1\|3411411_3413568_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_151072624.1\|3413658_3414072_+	hypothetical protein	NA	NA	NA	NA
WP_151072905.1\|3414424_3416524_+	AAA family ATPase	A0A1C9EG55	Acidianus_two-tailed_virus	1.8e-09	33.8
WP_151072625.1\|3416547_3417792_+	hypothetical protein	NA	NA	NA	NA
WP_151072626.1\|3417867_3418848_-	hypothetical protein	G3M9X5	Bacillus_virus	1.2e-16	25.9
WP_151072627.1\|3418967_3420110_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-97	52.3
WP_151072906.1\|3420241_3420682_-	DUF3293 domain-containing protein	NA	NA	NA	NA
WP_151069397.1\|3420743_3422120_-	group II intron reverse transcriptase/maturase	H7BVN7	unidentified_phage	4.2e-15	25.4
WP_151072628.1\|3422972_3425876_-	DUF499 domain-containing protein	NA	NA	NA	NA
WP_151072629.1\|3425889_3428745_-	DUF1156 domain-containing protein	K9MDJ7	Sulfolobus_virus	6.2e-29	25.1
WP_151072630.1\|3428786_3432305_-	DUF3883 domain-containing protein	A0A1B1IUI1	uncultured_Mediterranean_phage	2.1e-50	26.7
WP_151072631.1\|3432333_3433230_-	WYL domain-containing protein	NA	NA	NA	NA
WP_151072632.1\|3434234_3435200_+	DUF932 domain-containing protein	A0A0H4INH5	Stenotrophomonas_phage	3.7e-58	42.7
WP_151072633.1\|3435270_3436287_+	endonuclease	A6XMH8	Bacillus_virus	9.9e-54	40.4
WP_151072634.1\|3436280_3437192_+\|capsid	phage capsid protein	NA	NA	NA	NA
WP_151072635.1\|3437188_3438160_+	hypothetical protein	NA	NA	NA	NA
WP_151072636.1\|3438260_3438563_+	hypothetical protein	NA	NA	NA	NA
WP_151072637.1\|3438585_3438933_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167525741.1\|3439147_3440953_+	hypothetical protein	NA	NA	NA	NA
WP_151072638.1\|3441136_3441505_+	hypothetical protein	A0A1L7N0T7	Ralstonia_phage	1.0e-40	65.6
WP_151072639.1\|3441547_3441907_+	hypothetical protein	NA	NA	NA	NA
WP_151072640.1\|3442127_3443774_-	hypothetical protein	NA	NA	NA	NA
WP_151070364.1\|3443831_3444377_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_151070365.1\|3444345_3444870_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_151072641.1\|3444900_3445494_-	hypothetical protein	NA	NA	NA	NA
WP_151072642.1\|3445497_3446664_-	hypothetical protein	NA	NA	NA	NA
WP_151072908.1\|3447045_3447231_-	hypothetical protein	NA	NA	NA	NA
WP_151072643.1\|3447281_3448076_-	AAA family ATPase	NA	NA	NA	NA
WP_151072644.1\|3448079_3449405_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_151072645.1\|3449539_3450070_-	hypothetical protein	NA	NA	NA	NA
WP_151072646.1\|3450142_3452152_-	DNA mismatch repair protein	NA	NA	NA	NA
WP_151072647.1\|3452800_3453934_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_151072648.1\|3455381_3457211_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_151072649.1\|3457470_3458223_-	hypothetical protein	NA	NA	NA	NA
WP_063241213.1\|3458575_3459064_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	2.2e-19	47.5
3458448:3458495	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3623610 : 3629684

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063240918.1\|3623610_3624198_-	phosphoheptose isomerase	A0A067XQR2	Caulobacter_phage	3.4e-14	32.7
WP_063240917.1\|3624251_3624647_-	YraN family protein	NA	NA	NA	NA
WP_151072699.1\|3624662_3625583_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.5e-34	41.0
WP_063240973.1\|3625671_3626361_-	septal ring lytic transglycosylase RlpA family protein	H2BCY4	Synechococcus_phage	2.7e-18	53.2
WP_151072700.1\|3626733_3627384_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_151072701.1\|3627388_3628045_+	exonuclease	A0A2L0UZL4	Agrobacterium_phage	6.0e-36	41.0
WP_063240913.1\|3628253_3628487_+	hypothetical protein	NA	NA	NA	NA
WP_063240912.1\|3628568_3628928_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	4.7e-19	43.6
WP_151072702.1\|3629108_3629684_+	GNAT family N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	2.0e-19	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP032520

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP032520_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP032520_1

321671-321867

Orphan

Consensus_repeat	Method
AAAGGTGAGAGATTTTGT	CRT
GGCCTAACCAAAGGTGAGAGATTTTGTA	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP032520_1

>merge|NZ_CP032520|1|321671-321867|CRT,PILER-CR
GAAGGTGAGAGATTTTGTAACTCTAGTCGTCGTGTTTGAGTGTACGAGGCCTAGCTAAAGGTGAGAGATTTTGTGCTGCTGTTGTGTCTGACGGCGCCGAAGGCAATGGCCTTACCAAAGGTGAGAGATTTTGTACCCTTCGGCCGCACTTGAGCTTTTGAACAGCGGTGAAGCTTTCAAAAGGTGAGAGATTTTGT

>NZ_CP032520|1|1|321671-321867|CRT
GAAGGTGAGAGATTTTGT	AACTCTAGTCGTCGTGTTTGAGTGTACGAGGCCTAGCT
AAAGGTGAGAGATTTTGT	GCTGCTGTTGTGTCTGACGGCGCCGAAGGCAATGGCCTTACC
AAAGGTGAGAGATTTTGT	ACCCTTCGGCCGCACTTGAGCTTTTGAACAGCGGTGAAGCTTTCA
AAAGGTGAGAGATTTTGT

>NZ_CP032520|1|1|321672-321805|PILER-CR
AAGGTGAGAGATTTTGTAACTCTAGTCG	TCGTGTTTGAGTGTACGAGGCCTAGCTA
AAGGTGAGAGATTTTGTGCTGCTGTTGT	GTCTGACGGCGCCGAAGGCAATGGCCTTACCAA
AGGTGAGAGATTTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP032520.1\|WP_151073113.1\|313897_314194_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032520.1\|WP_151073112.1\|313416_313923_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032520.1\|WP_151073110.1\|309245_310289_+\|type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|377390
NZ_CP032520.1\|WP_151073111.1\|311541_313407_+\|conjugative-transfer-system-coupling-protein-TraD	unknown	unknown	gnl\|CDD\|274760
NZ_CP032520.1\|WP_151073122.1\|330244_330607_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|182138
NZ_CP032520.1\|WP_151073114.1\|314195_314813_+\|DUF4400-domain-containing-protein	unknown	unknown	gnl\|CDD\|379573
NZ_CP032520.1\|WP_151073109.1\|308469_309228_+\|conjugal-transfer-protein-TrbJ	unknown	unknown	gnl\|CDD\|184363
NZ_CP032520.1\|WP_151073120.1\|328024_329581_-\|recombinase-XerD	unknown	unknown	gnl\|CDD\|372139
NZ_CP032520.1\|WP_151073117.1\|319597_321115_-\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP032520.1\|WP_151073123.1\|331667_332111_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032520.1\|WP_151073121.1\|329990_330245_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225215
NZ_CP032520.1\|WP_151073275.1\|331093_331705_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|143393
NZ_CP032520.1\|WP_151073119.1\|327060_327495_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|334163
NZ_CP032520.1\|WP_151073272.1\|310288_311545_+\|type-VI-secretion-protein	unknown	unknown	gnl\|CDD\|377859
NZ_CP032520.1\|WP_151073124.1\|332461_332650_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032520.1\|WP_151073274.1\|322602_323640_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224113
NZ_CP032520.1\|WP_151073115.1\|314863_315718_+\|ATPase	unknown	unknown	unknown
NZ_CP032520.1\|WP_151073125.1\|332670_332922_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP032520.1\|WP_151073273.1\|315897_317619_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223288
NZ_CP032520.1\|WP_151073118.1\|323636_324605_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|319251

Protein	Function_ID	Function_description	E-value
NZ_CP032520.1\|WP_151073110.1\|309245_310289_+\|type-IV-secretion-system-protein	gnl\|CDD\|377390	pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein.	1.15062e-13
NZ_CP032520.1\|WP_151073111.1\|311541_313407_+\|conjugative-transfer-system-coupling-protein-TraD	gnl\|CDD\|274760	TIGR03743, SXT_TraD, conjugative coupling factor TraD, SXT/TOL subfamily. Members of this protein family are the putative conjugative coupling factor, TraD (or TraG), rather distantly related to the well-characterized TraD of the F plasmid. Members are associated with conjugative-transposon-like mobile genetic elements of the class that includes SXT, an antibiotic resistance transfer element in some Vibrio cholerae strains. [Mobile and extrachromosomal element functions, Other].	0
NZ_CP032520.1\|WP_151073122.1\|330244_330607_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.67141e-21
NZ_CP032520.1\|WP_151073114.1\|314195_314813_+\|DUF4400-domain-containing-protein	gnl\|CDD\|379573	pfam14348, DUF4400, Domain of unknown function (DUF4400). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 209 and 249 amino acids in length. There is a single completely conserved residue P that may be functionally important.	1.25074e-26
NZ_CP032520.1\|WP_151073109.1\|308469_309228_+\|conjugal-transfer-protein-TrbJ	gnl\|CDD\|184363	PRK13879, PRK13879, P-type conjugative transfer protein TrbJ.	0.00176286
NZ_CP032520.1\|WP_151073120.1\|328024_329581_-\|recombinase-XerD	gnl\|CDD\|372139	pfam12482, DUF3701, Phage integrase protein. This domain family is found in bacteria, and is approximately 100 amino acids in length. The family is found in association with pfam00589.	5.84088e-12
NZ_CP032520.1\|WP_151073117.1\|319597_321115_-\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	5.59739e-08
NZ_CP032520.1\|WP_151073121.1\|329990_330245_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|225215	COG2336, MazE, Growth regulator [Signal transduction mechanisms].	8.14e-13
NZ_CP032520.1\|WP_151073275.1\|331093_331705_+\|transcriptional-regulator	gnl\|CDD\|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	2.42873e-08
NZ_CP032520.1\|WP_151073119.1\|327060_327495_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|334163	pfam00589, Phage_integrase, Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.	6.7235e-07
NZ_CP032520.1\|WP_151073272.1\|310288_311545_+\|type-VI-secretion-protein	gnl\|CDD\|377859	pfam07514, TraI_2, Putative helicase. Some members of this family have been annotated as helicases.	2.06003e-13
NZ_CP032520.1\|WP_151073274.1\|322602_323640_+\|AAA-family-ATPase	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.8769e-43
NZ_CP032520.1\|WP_151073273.1\|315897_317619_+\|AAA-family-ATPase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	2.21691e-83
NZ_CP032520.1\|WP_151073118.1\|323636_324605_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|319251	cd16393, SPO0J_N, Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member. Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	3.35355e-46

>NZ_CP032520.1|WP_151073117.1|319597_321115_-|RepB-family-plasmid-replication-initiator-protein
MASSVVKRVTPLQYALDLFVEMAPAQTAIHEVSTDKDIGYHKNKVFARIVGLGMSARRFVDAAYFIVAQEPEVKESYEVSLSFFKWLMRYDSKNRKHFSSVIRSVKSSMLEVTSAPVVSVDASGRLLEGPGAAHDGDETDSDAANPDVDTVRVSDEEGDWLELIGRVSVRDGRIRFRVPVELQRLIKDPENSYWTSLLVTSKFTLIYARAIYDHILPNVSDERTDWLPLDVVRNLPGKSWANNAEFKYFKRDYLDKAVSQINELSDIELSYETRAGTPRSRKKDQIRFQMKRKDAALASKAAMLNSVALFQALEKEFALTDSQFERIADNRSVWTDERIQQAIEYVRWRIRSGDKVKRASGYLLDAIANNYRVSEADKEVERVQAKLADKAKEQVESKSAAQTAVAASIAAADAAAERRRLDEVRAARDYFETAEMTTREDLVRKFVTTKTIGTRTIERQGLKPADINATNIMERPNIATSFCSFVAGELRKAARNRANGQENVL
>NZ_CP032520.1|WP_151073273.1|315897_317619_+|AAA-family-ATPase
MSLAETLDKLNPSQREVVDCGAHCVAIAVPGAGKTATIAAKAAMLLSAPNATVGAVTFSKDAAVELRDRIGSLAGGVAKKRLMAGTFHSLAYKQLSIGVEGKRDIATDGDRIGLVTQALADTGLDWKVEDAITAIEAIKTNFGQVQAGTTEEVLYRAYQDSLERNGKIDFQDMLRLAVEGMQLGTIAPYPLTYLLVDEFQDTDPLQYQWIALHAQAGAITTVVGDDDQSIYGFRSALGFRGMESFIRQFDAQAVVLGKNYRCHAEILGAADKIIRHNRDRIPKVLVAHKGPGGEVAFQRFPDEYAEAVAAMEHLAPALNKNQSAAILARTNRILDPVEAVCRSHGIKYYRASGKSILGRPEAALMCNLLELVQKTRKTGIDALLSFVGIGTHELRLLHSSGKATGEQHQRKDLVVLGLSENSADKYRELMKRLAEWRALCDRQFYSLVLEGVHAWMMQHASADQARRAITTTYDVLSRLNGPFSDRLDFLRRDNNKPEPNALVLTTMHSSKGLEWDRVWIIRAEETVVPDEKGTESEERRLFYVAVTRARQDLQVSMTQKNPTSRFILEAELG
>NZ_CP032520.1|WP_151073115.1|314863_315718_+|ATPase
MTTTDLTPADAPLQEVGPTDDTVALLTEPPPTTLGSIDSSGDVETELAEMEQSADVLRNEGLISTADHEERKAQVERTRKLFRDLAPEDRQAIVRRRRELGLLILNRELAGAAVVPVALKLNHTRLRPLFEQWWPYMNRMSLNLQRFGAATFSRTELSTLENYLERELSKIEDYVDEQLRVAKAYREQREQEMRARYEIVFVPTIQRPSLALEVQAYSRFSVRALQVLIKFDQTMDQFDFMVWNGIRDQSDVNDEVTRFLRKFQPLGLRSYTTHLKLMTTVRGI
>NZ_CP032520.1|WP_151073114.1|314195_314813_+|DUF4400-domain-containing-protein
MANSRFASHIRLWLIFSPLMICTLAPFIQDESAFEISEAEQASVERVLGQDRADVAVTLANARFHQWFIESGVVKSSFSGSDAQTGIADGGASAFGRSWLQHFWLTIYRALYRAAVGHYWLVGAIVLFLALFNDGTVSRKIRAAGAGFANPVSFHVAAHGLMLCFGFGASALLLPLPMLATWWTFGICLVGLLCWRLAASFHVGK
>NZ_CP032520.1|WP_151073113.1|313897_314194_+|hypothetical-protein
MSLATLHNDARRLAIRLKQAPARMAAKLCGVDQALALHMHEWLTAPPPGAPAMPSAFTTGAAAACFALIKISVVKPGVFWGALVAFLSLPVLLTLRWS
>NZ_CP032520.1|WP_151073112.1|313416_313923_+|hypothetical-protein
MRSSLFRQIVKDYKLSAKLSPVFSLSPDLDDICTRVVDYIGVNFRVREEPLVKEMLADGIAAWRAARKHGDPNVAFMKGLFSRAHELYGKRYAAFKGEKYNVWYPFHESIPAFELRQPVGYVCRVVDEPAPGAITQRCAAFQLAARVLTGYTFTRYFENYDVAGNFAQ
>NZ_CP032520.1|WP_151073111.1|311541_313407_+|conjugative-transfer-system-coupling-protein-TraD
MNQYINHFRPIYEFRAVVGWALAVLLLLVSGMPNSGYFALGGMAFLLFRSSQVWRALRFRLSISTKWLTLVRIDDLLTQSRKLRSDDKDDDAMYLGTGYEWTQKHCQIAHDILRMPSSDIPGLPKWLPKDTVKAIEKAFAPENSIADRSPQGKSWIGGMESVRIPVPFHYKAMGGHTSISGTTGSGKTRTFELISTQVIHNPNDILIAIDPKNDPDWVARCKRECERTGRKFLYWKQAAPSQSIRLNPLENWSQPSEIPTRIAQLMEEGPFRQFAFLFIDRAVKGELYVGDKPNLRSILQYAQNGINNLLERGLERFFPEAGKADWEEEAAGYMQKVAQKAGGTRLDAMVSLYIDRFSKLGNGHEAIDGLISTYQHDRDHYGRIIASALPLLQMLATGETGLMLAPKADDFEDDREIWDIDKVIKQKAVLYVGADSLSNSMVAQAVMSMLLADIASVAGAIYNFYAKPPEIVLVVDEAAEAINEQLLQLLNKGRGAGFKAFVAYQTRSDFTAKLGNVAKMQQVLGNLNNQIVLRLEDIDTAQWFSEKAGTTAIRNLIVSSSTSTGTEAHIGEFSGSVSRSAQLEKVPLIPHDLVMQLPNLQYFLRISGGAVYQGRIPIIKD
>NZ_CP032520.1|WP_151073272.1|310288_311545_+|type-VI-secretion-protein
MTAHHHLTPPALLASHDSRLALVRQYANESNAEDFDTKWLSVLDRCAAWFSSMPLRPTEHAEPGGAFRATVEAAYFAMRLSGAQKFAADQTSDRRRLLEPQYLYALFLAACCSRLDEPCRHFQFHRQRDGAEWVPAAHGAFGAWLGDDSYRVTRREVPLPSERMRTALLAREILGAERLSAFDSQVLTDLFGAINPDPRPAGLETLLHKVVRQAIETVTQFELKARRAAFAPDTTPAPPAQALAEDSIPGASKPPAQAKTETAPVLETGTATPAEAKQSETTTGADPSFPAGLHPASSDAAAQHRASPNAVQLDGARSLRKVPPAEDPFKAIAGTSNLMREFFKALSQDAAAGKTKVTRVEGKVAVSKRSLGNYGIASETLIENLRKFKHLYKIVGQDILLVNEVGDLILPASQAPEA
>NZ_CP032520.1|WP_151073110.1|309245_310289_+|type-IV-secretion-system-protein
MLLRLLMLLVTAVLLHTSTAFAQSASPDANAASQSQGSAATPPSFSGPKGTVAESLKSWVGQFETFRNGLIASATSLSQAIRPETDKVAYGLALITLTLAGIQFAATNNPTTAWTDIFEAFMLLGIFAAIYVGYDQFAPGIYDWFRMLADKIAGTRSSNPALTLISVGAGFLDSYNQAMDAASGLSKLGVALSGLILIFTFVVCAIAALLYSFFIALGEVQAAVGIVVGPLAVALAFSDYSRRFFVSWLDFMIGASMYTVVASVMARLVSSAFTSTIVDQPEIGTTSLAGAAYALGVAMFMLLVALEIPKMAGAIFGSGGGLSGGAVGRLGMKAAGGLGGFLAKKGK
>NZ_CP032520.1|WP_151073109.1|308469_309228_+|conjugal-transfer-protein-TrbJ
MKKWIANIAIATSVLGASSAQAALPVTDWVGLIQTTMTALQSLKTEVYENTSIVYQYKMMANQLLQATGLDAGALTEQLDAIKGDIGKYEVYGGALKDLYGTVSDNADYLKKIQSMVVASGKTKEQWFEDQRQLLSNGDKTAKNLFSLGEQVFKNTQSVAQRRQKIQAQVKLSPTAQAAAQTTNQMLDVLASQNSDLLQLMSVRAQADADKEQQSVAKETQSAEAMRAISTAQDEELRQLRARVFSRKLQAD
>NZ_CP032520.1|WP_151073274.1|322602_323640_+|AAA-family-ATPase
MCGLSRQQVLHMAKSSDGVLPEGQTVGRGRTFTLAEARNWVQQVSDIYQTPLVAGPSDFEGKIIITSQLKGGSAKTTTTMCLAQGLSLRGRKVLVVDLDPQASLSELCGLYAEKEVFADDSVLPFIYNQNVEGGLEAKVQSTYWDGLDVIPAHTELVGAEYHLPAMQMKVPGFKFWQVLRDGLQPLRKKYDYIILDTSPSLSYLNLNALMAADAMVMPMVPENLDFFSSLSFWRLFSDVAKSFMRFEADKKYDFVSVLLTRVNYGPTSAAPVVRTWAQGAYRHWLAPFEVPASSVMSSGALAFTTVFDISSSHSQAKSLQRVRQPLVDYCRWVDDMFVKQWRPAQ
>NZ_CP032520.1|WP_151073118.1|323636_324605_+|ParB/RepB/Spo0J-family-partition-protein
MSNIREQMLAKTANIRSTADRKPDATRRANRTETAPGMAGALAAAQLRVRELEATGLPSELPVADIVPNPWQPRRTFNELKLTELAESIREVGLLQPIVVRRVEPGYQLVAGERRWRAHKMLGLENIKAVVVDCSDADMIVLALVENIGRDDLSDYEIALSIQRSEKEFPNRTRLAEAVGLSRRGLYKFMAFYDLPDFVKHDLDLQPNLLGSNAADALASCLKKHGEAGVSATRELWTDVVAGHLDQGKLAAAVTALATKKVSGSAARERSIEKFFAGQNHAGSITKDIKNFTVKIKTGILSDSQETRIRQFISELFSGTPN
>NZ_CP032520.1|WP_151073119.1|327060_327495_-|tyrosine-type-recombinase/integrase
MITTTLLRLAEDSTLPLDEAERCLQRRAAPHALRHTFATQEAANDIPPDIVQRLLGYASLQKSSLYVHWRKRSLQRIARGREPHRLSPADPAILDSGRARTYQWGYVGADDCERYKNFLVQLDALWIGHKAPQTSACCRPFADR
>NZ_CP032520.1|WP_151073120.1|328024_329581_-|recombinase-XerD
MAQDPSLNAVTKLTRTEFAVVRAYAQGMRPVDIANRYLLDPDEDEHLSEAQAIQRIQALRDRLVQFALQHGRPEIAGMFEALRARSGVGMSRRVDAVSALEQLGQGYPQPQHEVSLWFKPSLARRLMAANIRRIEDLTSLANRRGSSWWRAVPRIGAQSAEVIAHWLVRQRPAMGAAAVNAYVLPPAAHAHRDALVPLALAPGMPYPVPLEHMLEPAPNTAAGPALASDLAFVRAWLQERRTPHTRNSYRREAERLLLWSAARKAGLQALEACDLHAYEEFLADPQPAAFWCGPSGARDRMHWRPFEGPLGPSSVAAALRVVRALLRAMVKAGHLASAPLIPRQTAAAAPTAQITPFVQPDVEAFVVWLGEARQGPRHRAALAVVQLMRSAGLPLSELAALRCASLQSSAEGTFLRSASSRQQLVALHTAARQALEAHWADRGWPSMMPPAQAALLAPAVHPATTRGRNKRLAGIAAGYSATGLDQLLRSLWRRFCEQRGVPSEGFTPGKLRTRATRA
>NZ_CP032520.1|WP_151073121.1|329990_330245_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MRKSATLTIQKWGNSLAVRIPTAVARSAHFAEGQEVEVSVDEIGVTVRPVGRRALTLAEKLALFDPVKHGGEAMATQRVGAEAI
>NZ_CP032520.1|WP_151073122.1|330244_330607_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MVGKVWVPERRDIIWIDCNPQAGREMKDMHPMLVLSPRPFNERTSIVIGLPMTTAAYNDTNPFAIKFQGPKEKDSYVLAHQPKSFDWRARNAKAHPWKQAPLEVFSAACEQLNQIIAIAE
>NZ_CP032520.1|WP_151073275.1|331093_331705_+|transcriptional-regulator
MGTSFVDALFTKSQQRVMAVLFGAPERSFYANEIVALAGAGVGAVHRELAKLEGAGLLTSHRVGNQRHYQANREAPIFEELRSIVSKTLGVGEILRDALQPLWTRITLAFVFGSVAKASDHAGSDVDVLILADDLSYGEVLATLDHASARLGRKVNPTVFSPTEFVKRIQEGRAFVIRVLDQPKIFVKGNPDELDSLARAAKS
>NZ_CP032520.1|WP_151073123.1|331667_332111_+|hypothetical-protein
MSLTPSPALQNLERVKKLKAEPPDSRECAALLRSAEIRLGDAQNVSLSIESQFDLVYNAAHAAALAALRRHGYRSDNRYLVFQCLQHTLHWSAEQWRLLDVAHHKRNLAEYEGDLTIDQAFVKELIAAVRQLVDAVRALLVSEGWGG
>NZ_CP032520.1|WP_151073124.1|332461_332650_+|hypothetical-protein
MLSKLENGKGVNFERVLRVMDGLGLAMLVVYKEHVPWLEQVAAHAVKIGRGCCQGKHTWLEE
>NZ_CP032520.1|WP_151073125.1|332670_332922_-|hypothetical-protein
MSHRLRYAAGSRITSQQVDLRFVRENFGRASIATTSTNLCSAEDARHEVTQAQHRIGWSHKAKAQPLESEWHFRTDRDVGFCA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP032520_1	1.1\|321689\|38\|NZ_CP032520\|CRT	321689-321726	38	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	321689-321726	1.0
NZ_CP032520_1	1.2\|321745\|42\|NZ_CP032520\|CRT	321745-321786	42	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	321745-321786	1.0
NZ_CP032520_1	1.3\|321805\|45\|NZ_CP032520\|CRT	321805-321849	45	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	321805-321849	1.0
NZ_CP032520_1	1.4\|321700\|28\|NZ_CP032520\|PILER-CR	321700-321727	28	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	321690-321717	1.0
NZ_CP032520_1	1.5\|321756\|33\|NZ_CP032520\|PILER-CR	321756-321788	33	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	321745-321777	1.0

1. spacer 1.1|321689|38|NZ_CP032520|CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

aactctagtcgtcgtgtttgagtgtacgaggcctagct	CRISPR spacer
aactctagtcgtcgtgtttgagtgtacgaggcctagct	Protospacer
**************************************

2. spacer 1.2|321745|42|NZ_CP032520|CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gctgctgttgtgtctgacggcgccgaaggcaatggccttacc	CRISPR spacer
gctgctgttgtgtctgacggcgccgaaggcaatggccttacc	Protospacer
******************************************

3. spacer 1.3|321805|45|NZ_CP032520|CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

acccttcggccgcacttgagcttttgaacagcggtgaagctttca	CRISPR spacer
acccttcggccgcacttgagcttttgaacagcggtgaagctttca	Protospacer
*********************************************

4. spacer 1.4|321700|28|NZ_CP032520|PILER-CR matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

actctagtcgtcgtgtttgagtgtacga	CRISPR spacer
actctagtcgtcgtgtttgagtgtacga	Protospacer
****************************

5. spacer 1.5|321756|33|NZ_CP032520|PILER-CR matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gctgctgttgtgtctgacggcgccgaaggcaat	CRISPR spacer
gctgctgttgtgtctgacggcgccgaaggcaat	Protospacer
*********************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

59546 : 96441

Salmonella_phage(60.0%)

integrase,transposase

attL 50686:50700|attR 103182:103196

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
50686:50700	attL	NA	NA	NA	NA
WP_151069191.1\|59546_60782_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151069190.1\|60666_62295_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151069189.1\|62291_64610_+	hypothetical protein	NA	NA	NA	NA
WP_115737136.1\|64602_65103_+	hypothetical protein	NA	NA	NA	NA
WP_151072924.1\|65416_66112_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_151072925.1\|66108_66612_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_151072926.1\|68926_69352_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_001138070.1\|69795_72762_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
WP_003124096.1\|72764_73325_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	2.1e-50	88.6
WP_003132006.1\|73455_74445_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_003132004.1\|74441_74678_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_000995360.1\|74674_75040_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_003156770.1\|75057_76743_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	5.5e-41	29.3
WP_003131987.1\|76814_77090_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_003131974.1\|77102_77453_-	mercuric ion transporter MerT	NA	NA	NA	NA
WP_003131969.1\|77524_77959_+	mercury resistance transcriptional regulator MerR	NA	NA	NA	NA
WP_151072917.1\|78064_78493_+	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_151073258.1\|78492_78948_+	RES domain-containing protein	NA	NA	NA	NA
WP_151072927.1\|79897_80821_-	hypothetical protein	NA	NA	NA	NA
WP_151072928.1\|82603_83779_+	DUF1016 family protein	A0A0U2BZN7	Salmonella_phage	9.3e-64	76.2
WP_151072929.1\|83891_84455_+	hypothetical protein	NA	NA	NA	NA
WP_151072930.1\|84447_86811_+	DEAD/DEAH box helicase family protein	M1HKT1	Acanthocystis_turfacea_Chlorella_virus	1.7e-32	29.7
WP_151072931.1\|87030_87366_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_151072932.1\|87708_88743_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_151072933.1\|89023_89251_-	hypothetical protein	NA	NA	NA	NA
WP_151072934.1\|90299_90617_+	hypothetical protein	NA	NA	NA	NA
WP_115737136.1\|90884_91385_-	hypothetical protein	NA	NA	NA	NA
WP_151069189.1\|91377_93696_-	hypothetical protein	NA	NA	NA	NA
WP_151069190.1\|93692_95321_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151069191.1\|95205_96441_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
103182:103196	attR	NA	NA	NA	NA

DBSCAN-SWA_2

347128 : 401569

Pseudomonas_phage(30.0%)

capsid,integrase,transposase

attL 337196:337211|attR 404257:404272

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
337196:337211	attL	NA	NA	NA	NA
WP_151073135.1\|347128_348739_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_151073136.1\|348746_349613_+	AAA family ATPase	NA	NA	NA	NA
WP_151073137.1\|349572_350106_+\|transposase	transposase	NA	NA	NA	NA
WP_151073138.1\|350815_351175_+	hypothetical protein	NA	NA	NA	NA
WP_151073139.1\|351319_351538_+	hypothetical protein	NA	NA	NA	NA
WP_135707220.1\|351982_352282_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_151073141.1\|352256_352514_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_151073142.1\|352553_353885_+	hypothetical protein	NA	NA	NA	NA
WP_116322054.1\|354030_355257_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_151073143.1\|355343_355922_+	hypothetical protein	NA	NA	NA	NA
WP_151073144.1\|356621_356810_+	hypothetical protein	NA	NA	NA	NA
WP_151073145.1\|356940_357147_+\|transposase	IS1 family transposase	NA	NA	NA	NA
WP_151073146.1\|357209_357731_-	hypothetical protein	A0A2H4J2P5	uncultured_Caudovirales_phage	1.5e-37	59.9
WP_151073147.1\|357868_358948_-	hypothetical protein	NA	NA	NA	NA
WP_151073148.1\|359146_360148_+	hypothetical protein	NA	NA	NA	NA
WP_167525752.1\|361026_362001_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_151073150.1\|362144_362879_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_151073151.1\|362923_364078_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_151073152.1\|364099_364876_-	citryl-CoA lyase	NA	NA	NA	NA
WP_151073153.1\|364905_365658_-	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	7.9e-16	30.1
WP_151073154.1\|365826_366924_+	CoA transferase	NA	NA	NA	NA
WP_151073155.1\|367027_368164_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_151073156.1\|368204_369395_+	lipid-transfer protein	NA	NA	NA	NA
WP_151073157.1\|369427_369877_+	MaoC family dehydratase	NA	NA	NA	NA
WP_151073158.1\|369899_370319_+	MaoC family dehydratase	NA	NA	NA	NA
WP_151073159.1\|370355_371189_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_151073160.1\|371311_372871_+	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.3e-32	24.5
WP_151073161.1\|372969_374541_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.7e-26	23.9
WP_151073162.1\|374612_375398_+	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase	NA	NA	NA	NA
WP_151073163.1\|375505_376477_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_151073164.1\|376572_376992_-	MaoC family dehydratase	NA	NA	NA	NA
WP_151073165.1\|377015_377465_-	MaoC family dehydratase	NA	NA	NA	NA
WP_151073166.1\|377507_378647_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_151073167.1\|378742_380437_-	AMP-binding protein	Q75ZG1	Hepacivirus	3.3e-38	33.1
WP_151073168.1\|380475_381465_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_151073169.1\|381631_384445_-	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_151073170.1\|384690_385878_+	lipid-transfer protein	NA	NA	NA	NA
WP_151073171.1\|385908_386739_+	SDR family NAD(P)-dependent oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-18	29.6
WP_151073172.1\|387040_388252_+	CoA transferase	NA	NA	NA	NA
WP_151073173.1\|388285_389449_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_151073174.1\|389464_389941_+	acyl dehydratase	NA	NA	NA	NA
WP_151073175.1\|389946_390732_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_151073176.1\|390781_391372_+	hypothetical protein	NA	NA	NA	NA
WP_167525753.1\|391524_392676_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151069397.1\|393137_394514_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.1e-28	30.4
WP_151073178.1\|394845_395166_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_151073179.1\|395240_396182_+	hypothetical protein	A0A2D1GN57	Marinobacter_phage	4.6e-29	31.7
WP_151073180.1\|396181_396451_+	hypothetical protein	NA	NA	NA	NA
WP_151073181.1\|396450_396888_+	hypothetical protein	NA	NA	NA	NA
WP_151073182.1\|397215_398742_+	DEAD/DEAH box helicase family protein	A0A0H5ARP5	Pseudomonas_phage	1.2e-66	37.2
WP_151073183.1\|398805_399702_+	hypothetical protein	A0A2H4GY91	Pseudomonas_phage	3.3e-29	31.9
WP_151073184.1\|399723_400170_+	hypothetical protein	NA	NA	NA	NA
WP_151073185.1\|400250_400550_+	hypothetical protein	NA	NA	NA	NA
WP_151073186.1\|400576_401569_+\|capsid	phage major capsid protein	NA	NA	NA	NA
404257:404272	attR	NA	NA	NA	NA

DBSCAN-SWA_3

423218 : 546804

104

Bacillus_phage(21.05%)

integrase,transposase

attL 432498:432521|attR 550807:550830

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_167525755.1\|423218_424499_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151073205.1\|424591_425794_+	KfrA protein	NA	NA	NA	NA
WP_151073206.1\|425777_425981_+	H-NS histone family protein	NA	NA	NA	NA
WP_151073207.1\|426132_426486_+	hypothetical protein	NA	NA	NA	NA
WP_151073208.1\|426577_429577_+\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	3.6e-51	20.8
WP_151073209.1\|429569_429914_+\|transposase	transposase	NA	NA	NA	NA
WP_151073210.1\|430464_430812_-	hydroxyquinol 1,2-dioxygenase	NA	NA	NA	NA
WP_167525756.1\|430943_431450_-	CzcE family metal-binding protein	NA	NA	NA	NA
WP_151073212.1\|432233_432584_-	hypothetical protein	NA	NA	NA	NA
432498:432521	attL	NA	NA	NA	NA
WP_151073213.1\|432580_435751_-	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
WP_151073214.1\|435747_437292_-	efflux RND transporter periplasmic adaptor subunit	S5VL44	Leptospira_phage	2.8e-07	27.0
WP_151073215.1\|437288_438590_-	TolC family protein	NA	NA	NA	NA
WP_151073280.1\|438660_439065_-	hypothetical protein	NA	NA	NA	NA
WP_151073216.1\|439321_439750_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_151073281.1\|439812_442185_+	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	5.3e-90	37.6
WP_151073282.1\|442783_443020_+	hypothetical protein	NA	NA	NA	NA
WP_151073217.1\|443173_443476_+	hypothetical protein	NA	NA	NA	NA
WP_151073218.1\|443519_443828_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_167525757.1\|444099_444291_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_151073220.1\|444357_445017_+	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_151073221.1\|445075_445681_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_151073222.1\|445726_446050_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_151073223.1\|446148_446823_-	c-type cytochrome	NA	NA	NA	NA
WP_151073224.1\|447086_447836_+	slipin family protein	A0A1V0SB59	Catovirus	4.8e-13	26.0
WP_151073225.1\|447966_449664_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151073226.1\|449783_450044_+	hypothetical protein	NA	NA	NA	NA
WP_167525758.1\|450209_450365_-	hypothetical protein	NA	NA	NA	NA
WP_151073227.1\|450432_452760_+	AAA family ATPase	NA	NA	NA	NA
WP_151073283.1\|452774_452924_-	filamentous hemagglutinin N-terminal domain-containing protein	NA	NA	NA	NA
WP_151073228.1\|452965_454363_-	hypothetical protein	R9TRQ8	Vibrio_phage	1.4e-21	26.4
WP_151073229.1\|454772_455294_-	TIR domain-containing protein	NA	NA	NA	NA
WP_151073230.1\|455789_456422_-	hypothetical protein	NA	NA	NA	NA
WP_151073231.1\|456771_457104_+	hypothetical protein	NA	NA	NA	NA
WP_151073232.1\|457218_458883_+	hypothetical protein	NA	NA	NA	NA
WP_151073285.1\|460017_461097_+	hypothetical protein	NA	NA	NA	NA
WP_151073284.1\|461150_461954_+	hypothetical protein	NA	NA	NA	NA
WP_151073233.1\|461971_463339_+	hypothetical protein	NA	NA	NA	NA
WP_151073234.1\|463351_463627_+	hypothetical protein	NA	NA	NA	NA
WP_167525759.1\|463856_464777_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_151073236.1\|464871_466422_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	5.4e-35	27.4
WP_151073237.1\|466431_467610_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_151073238.1\|467658_468645_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_151073239.1\|468647_469790_+	CoA transferase	NA	NA	NA	NA
WP_151073240.1\|469897_471055_+	porin	NA	NA	NA	NA
WP_151073286.1\|471652_473065_+	DUF1214 domain-containing protein	NA	NA	NA	NA
WP_151073241.1\|473142_474171_+	DUF1254 domain-containing protein	A0A2P0VP21	Tetraselmis_virus	5.8e-54	38.6
WP_151073242.1\|474696_475677_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151073243.1\|475673_476627_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_151073244.1\|476623_477622_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	3.8e-18	24.1
WP_151073245.1\|477840_480840_+\|transposase	Tn3 family transposase	A0A125RQ78	Bacillus_phage	1.9e-52	20.9
WP_151073246.1\|480832_481177_+\|transposase	transposase	NA	NA	NA	NA
WP_151073247.1\|482205_482544_-	hypothetical protein	NA	NA	NA	NA
WP_151073248.1\|482540_485711_-	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	1.0e-64	21.7
WP_151073249.1\|485707_487273_-	efflux RND transporter periplasmic adaptor subunit	S5VL44	Leptospira_phage	4.1e-06	26.0
WP_151023068.1\|487269_488577_-	TolC family protein	NA	NA	NA	NA
WP_115737209.1\|488649_489048_-	copper resistance protein	NA	NA	NA	NA
WP_062799422.1\|489209_489431_-	hypothetical protein	NA	NA	NA	NA
WP_145987315.1\|490025_490244_-	hypothetical protein	NA	NA	NA	NA
WP_116322061.1\|491230_491533_+	hypothetical protein	NA	NA	NA	NA
WP_151073250.1\|491780_492179_+	hypothetical protein	NA	NA	NA	NA
WP_151073251.1\|492358_493237_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_151073252.1\|493585_494062_+	CzcE family metal-binding protein	NA	NA	NA	NA
WP_115737205.1\|494191_494428_+	hypothetical protein	NA	NA	NA	NA
WP_115737204.1\|494729_496466_+	phosphoethanolamine--lipid A transferase	NA	NA	NA	NA
WP_082371458.1\|496473_497286_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_115737294.1\|497250_498516_-	type II restriction endonuclease	NA	NA	NA	NA
WP_115737203.1\|498685_498961_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_115737202.1\|498974_501416_+	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.5e-87	36.4
WP_053823085.1\|501480_501897_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_053821772.1\|501958_502489_+	c-type cytochrome	NA	NA	NA	NA
WP_082371627.1\|503109_503307_+	hypothetical protein	NA	NA	NA	NA
WP_082371461.1\|503522_503870_-	CzcE family metal-binding protein	NA	NA	NA	NA
WP_053821774.1\|504255_504732_-	cupredoxin family protein	NA	NA	NA	NA
WP_115737201.1\|504800_505718_-	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_053823086.1\|505725_506112_-	copper homeostasis periplasmic binding protein CopC	NA	NA	NA	NA
WP_053823087.1\|506150_507140_-	copper resistance protein B	NA	NA	NA	NA
WP_053821776.1\|507454_509341_-	copper resistance system multicopper oxidase	NA	NA	NA	NA
WP_053821777.1\|509543_510230_+	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	4.6e-31	34.4
WP_053821778.1\|510226_511621_+	heavy metal sensor histidine kinase	A0A1V0SGX0	Hokovirus	5.6e-07	27.7
WP_082371462.1\|511711_512779_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	3.1e-05	27.2
WP_115737200.1\|512846_513905_-	porin	NA	NA	NA	NA
WP_053821780.1\|514838_515123_-	periplasmic Cu(I)/Cu(II)-binding protein CopK	NA	NA	NA	NA
WP_116322066.1\|515212_515599_-	hypothetical protein	NA	NA	NA	NA
WP_115737199.1\|515837_516896_-	copper resistance protein B	NA	NA	NA	NA
WP_115737198.1\|516826_518764_-	copper resistance system multicopper oxidase	NA	NA	NA	NA
WP_062799392.1\|519029_519356_+	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_053821782.1\|519553_521368_+	glycoside hydrolase family 15 protein	NA	NA	NA	NA
WP_062799390.1\|521368_522364_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_151073253.1\|522385_524971_+	DNA polymerase III subunit epsilon	NA	NA	NA	NA
WP_115737292.1\|525676_525904_-	hypothetical protein	NA	NA	NA	NA
WP_115737291.1\|526961_528611_-	c-type cytochrome	NA	NA	NA	NA
WP_115737196.1\|529656_530775_+	TolC family protein	NA	NA	NA	NA
WP_062799361.1\|530771_532313_+	efflux RND transporter periplasmic adaptor subunit	S5VL44	Leptospira_phage	6.8e-06	25.9
WP_151073254.1\|532309_535480_+	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
WP_053821791.1\|535476_535830_+	hypothetical protein	NA	NA	NA	NA
WP_082371464.1\|536229_537126_-	sterol desaturase family protein	NA	NA	NA	NA
WP_053821792.1\|537286_537919_+	cation transporter	NA	NA	NA	NA
WP_115737195.1\|538000_541033_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.4e-150	43.9
WP_053821794.1\|541022_541517_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_062799357.1\|541644_542337_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_053821795.1\|542333_542759_+	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_167525760.1\|543024_544265_-\|transposase	IS3-like element ISRme15 family transposase	Q8W6R2	Burkholderia_virus	5.5e-131	79.9
WP_115737194.1\|544767_545292_+	OmpH family outer membrane protein	NA	NA	NA	NA
WP_151070220.1\|545475_546804_-\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	2.4e-52	29.1
550807:550830	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP032518

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP032519

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP032520

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection