CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP044494	Streptococcus mutans strain MD plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP044493	Streptococcus mutans strain MD chromosome, complete genome	3 crisprs	DEDDh,cas3,csm6,csa3,DinG,csn2,cas2,cas1,cas9,WYL,cas6e,cas5,cas7,cse2gr11,cas8e,cas4,cas8c	0	25	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP044493_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044493_1

1291301-1291732

TypeII

Consensus_repeat	Method
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	PILER-CR
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CRISPRCasFinder
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CRT

6 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP044493_1

>merge|NZ_CP044493|1|1291301-1291732|PILER-CR,CRISPRCasFinder,CRT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACAATCTCTTTAACATTTATCTGACAATCAGAGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACTTGAAACCTCGTCTCAGAAAATCAATTGCAGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACAAACGGTCGGATTGAATGAAGTTATGTATAGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACCGCGACTCGCGTTGTGCTTCTTGCTCGTTTGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACGTCTATTAACAAAACGCGAGAAGAGCAACTGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAACGCGTCACGCAGTCGCTTTTAAAGTTTGCCTGTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

>NZ_CP044493|1|1|1291301-1291732|PILER-CR
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AATCTCTTTAACATTTATCTGACAATCAGA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	TTGAAACCTCGTCTCAGAAAATCAATTGCA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AAACGGTCGGATTGAATGAAGTTATGTATA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CGCGACTCGCGTTGTGCTTCTTGCTCGTTT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	GTCTATTAACAAAACGCGAGAAGAGCAACT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	GCGTCACGCAGTCGCTTTTAAAGTTTGCCT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

>NZ_CP044493|1|1|1291301-1291732|CRISPRCasFinder
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AATCTCTTTAACATTTATCTGACAATCAGA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	TTGAAACCTCGTCTCAGAAAATCAATTGCA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AAACGGTCGGATTGAATGAAGTTATGTATA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CGCGACTCGCGTTGTGCTTCTTGCTCGTTT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	GTCTATTAACAAAACGCGAGAAGAGCAACT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	GCGTCACGCAGTCGCTTTTAAAGTTTGCCT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

>NZ_CP044493|1|1|1291301-1291732|CRT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AATCTCTTTAACATTTATCTGACAATCAGA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	TTGAAACCTCGTCTCAGAAAATCAATTGCA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	AAACGGTCGGATTGAATGAAGTTATGTATA
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	CGCGACTCGCGTTGTGCTTCTTGCTCGTTT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	GTCTATTAACAAAACGCGAGAAGAGCAACT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC	GCGTCACGCAGTCGCTTTTAAAGTTTGCCT
GTTGTACAGTTACTTAAATCTTGAGAGTACAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044493.1\|WP_002264334.1\|1287744_1289496_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|369832
NZ_CP044493.1\|WP_032538907.1\|1298811_1299690_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP044493.1\|WP_151416351.1\|1280357_1281998_-\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
NZ_CP044493.1\|WP_002279852.1\|1301314_1302490_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341026
NZ_CP044493.1\|WP_002279023.1\|1290258_1291152_+\|LexA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|119397
NZ_CP044493.1\|WP_151416359.1\|1302665_1305194_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP044493.1\|WP_151416358.1\|1299814_1301305_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180854
NZ_CP044493.1\|WP_151416355.1\|1293155_1294064_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP044493.1\|WP_151416360.1\|1305936_1306710_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP044493.1\|WP_151416353.1\|1283038_1283647_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP044493.1\|WP_151416352.1\|1282317_1282974_+\|Pr6Pr-family-membrane-protein	unknown	unknown	unknown
NZ_CP044493.1\|WP_002262720.1\|1289658_1289943_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP044493.1\|WP_151416357.1\|1297828_1298704_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP044493.1\|WP_002262717.1\|1285137_1286973_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP044493.1\|WP_151416356.1\|1294232_1297610_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
NZ_CP044493.1\|WP_002299167.1\|1292829_1293153_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP044493.1\|WP_002267567.1\|1284281_1285109_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP044493.1\|WP_151416354.1\|1291783_1292833_-\|CRISPR-associated-protein-Cas7	csn2	cd12217_csn2_CAS-II-A	gnl\|CDD\|213410
NZ_CP044493.1\|WP_002262715.1\|1283726_1284203_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP044493.1\|WP_151416350.1\|1279082_1280165_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587

Protein	Function_ID	Function_description	E-value
NZ_CP044493.1\|WP_002264334.1\|1287744_1289496_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	3.8301e-110
NZ_CP044493.1\|WP_032538907.1\|1298811_1299690_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	6.91267e-21
NZ_CP044493.1\|WP_151416351.1\|1280357_1281998_-\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	6.77204e-12
NZ_CP044493.1\|WP_002279852.1\|1301314_1302490_+\|MFS-transporter	gnl\|CDD\|341026	cd17473, MFS_arabinose_efflux_permease_like, Putative arabinose efflux permease family transporters of the Major Facilitator Superfamily. This family includes a group of putative arabinose efflux permease family transporters, such as alpha proteobacterium quinolone resistance protein NorA (characterized Staphylococcus aureus Quinolone resistance protein NorA belongs to a different group), Desulfovibrio dechloracetivorans bacillibactin exporter, Vibrio aerogenes antiseptic resistance protein. The biological function of those transporters remain unclear. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.08633e-50
NZ_CP044493.1\|WP_002279023.1\|1290258_1291152_+\|LexA-family-transcriptional-regulator	gnl\|CDD\|119397	cd06529, S24_LexA-like, Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The LexA-like proteins contain two-domains: an N-terminal DNA binding domain and a C-terminal domain (CTD) that provides LexA dimerization as well as cleavage activity. They undergo autolysis, cleaving at an Ala-Gly or a Cys-Gly bond, separating the DNA-binding domain from the rest of the protein. In the presence of single-stranded DNA, the LexA, UmuD and MucA proteins interact with RecA, activating self cleavage, thus either derepressing transcription in the case of LexA or activating the lesion-bypass polymerase in the case of UmuD and MucA. The LexA proteins are serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases. LexA sequence homologs are found in almost all of the bacterial genomes sequenced to date, covering a large number of phyla, suggesting both, an ancient origin and a widespread distribution of lexA and the SOS response.	2.38156e-23
NZ_CP044493.1\|WP_151416359.1\|1302665_1305194_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	5.90174e-103
NZ_CP044493.1\|WP_151416358.1\|1299814_1301305_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|180854	PRK07121, PRK07121, FAD-binding protein.	2.52154e-42
NZ_CP044493.1\|WP_151416355.1\|1293155_1294064_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.78749e-120
NZ_CP044493.1\|WP_151416360.1\|1305936_1306710_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.17934e-131
NZ_CP044493.1\|WP_151416356.1\|1294232_1297610_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	0
NZ_CP044493.1\|WP_002262720.1\|1289658_1289943_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	8.64754e-07
NZ_CP044493.1\|WP_151416357.1\|1297828_1298704_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	2.45754e-38
NZ_CP044493.1\|WP_002262717.1\|1285137_1286973_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP044493.1\|WP_002299167.1\|1292829_1293153_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	3.35231e-27
NZ_CP044493.1\|WP_002267567.1\|1284281_1285109_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.45954e-06
NZ_CP044493.1\|WP_151416354.1\|1291783_1292833_-\|CRISPR-associated-protein-Cas7	gnl\|CDD\|213410	cd12217, Stu0660_Csn2, Stu0660-like CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. This family of Csn2 proteins includes Stu0660, the proteins are larger than other (canonical) Csn2 proteins as they have an additional alpha-helical C-terminal domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	6.89168e-120
NZ_CP044493.1\|WP_002262715.1\|1283726_1284203_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.76682e-16
NZ_CP044493.1\|WP_151416350.1\|1279082_1280165_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	5.30072e-94

>NZ_CP044493.1|WP_002279023.1|1290258_1291152_+|LexA-family-transcriptional-regulator
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFASKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTIIHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKTKAIHHGQIIVIIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT
>NZ_CP044493.1|WP_002262720.1|1289658_1289943_-|helix-turn-helix-transcriptional-regulator
MQFVWESNGKLKGDAEVEKLTLRALRVNYSLSPKEVADCLGIPQHTLLSYEEDSSEIPIQLANDLANYYDISLDSIFFGKNSDLKQKFKNKNNR
>NZ_CP044493.1|WP_002264334.1|1287744_1289496_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKSKTAKITLLSSLALAAFGATNVFADEASTQLNSDTVAAPTADTQASEPAATEKEQSPVVAVVESHTQGNTTTTTSQVTSKELEDAKANANQEGLEVTETEAQKQPSVEAADADNKAQAQTINTAVADYQKAKAEFPQKQEQYNKDFEKYQSDVKEYEAQKAAYEQYKKEVAQGLASGRVEKAQGLVFINEPEAKLSIEGVNQYLTKEARQKHATEDILQQYNTDNYTASDFTQANPYDPKEDTWFKMKVGDQISVTYDNIVNSKYNDKKISKVKINYTLNSSTNNEGSALVNLFHDPTKTIFIGAQTSNAGRNDKISVTMQIIFYDENGNEIDLSGNNAIMSLSSLNHWTTKYGDHVEKVNLGDNEFVKIPGSSVDLHGNEIYSAKDNQYKANGATFNGDGADGWDAVNADGTPRAATAYYGAGAMTYKGEPFTFTVGGNDQNLPTTIWFATNSAVAVPKDPGAKPTPPEKPELKKPTVTWHKNLVVETKTEEVPPVTPPTTPDEPTPEKPKTPEDPQSPVVAKSVSFRTARKGEMRVRERDYQPTLPHTGAAKQNGLATLGAISTAFAAATLIAARKKEN
>NZ_CP044493.1|WP_002262717.1|1285137_1286973_-|elongation-factor-4
MTIEQLKNRQEKIRNFSIIAHIDHGKSTLADRILEQTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYKAKNGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPKGDVEAPLKALIFDSVYDAYRGVILQIRVMDGMVKPGDKIELMSNGKTFDVTEVGIFTPKAVNRDFLATGDVGYLAASIKTVADTRVGDTVTLADCPAEAPLHGYKQLNPMVFAGIYPIDSSKYNDMREALEKLQLNDASLHFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVYTTDGERLEVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEYVGAVMELSQRKRGDFVTMDYIDNNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDISEYRKSKLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDDDDKKK
>NZ_CP044493.1|WP_002267567.1|1284281_1285109_-|alpha/beta-hydrolase
MAALNKEMVNTLLGPIYTCHREGNPCFVFLSGAGFFSTADNFANIIDKLPDSIGILTIDAPNSGYSPVSNQANVGLRDWVNAILMIFEHFKFQSYLLCVHSIGGFAALQIMNQSSKACLGFIGLEPTTAMIYRAGFSSDLYPQLALRRQKLKTAADRLNYLKDLSRSHFSSQQFKQLWRGYDYCQRQLNDVQSLPDFKIRLALGEEDFKTGISEKIPSIVFSESFREKEYLESEYLNKHTQTKLILCGQHHYLHWSETNSILEKVEQLLSNHEKL
>NZ_CP044493.1|WP_002262715.1|1283726_1284203_-|GNAT-family-N-acetyltransferase
MSIRLAQVTDIPVLKELLNQIFQVHQTVRPDLFKNTDKGSKYSETELKELLQDESKPIFVYTDGKNRVLGHLFLVIKETKGSSVSKPLKTLFIDDLCVSKEARGQKIGQELFEFALKYAKKLGCYDLTLNVWNDNKGALAFYERQGLKARETKMEKIL
>NZ_CP044493.1|WP_151416353.1|1283038_1283647_-|hypothetical-protein
MPRRRASRRKSKKKAVFSILLTGITLIIIGLAVYFISAYFTNTKKTANKEKTQTHIVNPKKDPEEKKEADSASKATSKFDLTTIATGDYSSAAGTWQNELGDQLKFNASGLESATIQNATDFTISSGQATNDGLYQATLTSADSTVVYNLLFVKGGTAIPENYFTTGYSDTSDTSRDRLYISSQTTFGSDDFSKGIFYKSKN
>NZ_CP044493.1|WP_151416352.1|1282317_1282974_+|Pr6Pr-family-membrane-protein
MSKTQAFRSLIALLGLIGVSIQIKQSGWGMLLYYTTLSNVIVFSFLTYLVIKEKRNGSINSNPKLLRLKGGVTMTIMITFMVYHFLLAPKVRAYDYYTIRIFLVHYIVPLSTIFDTLICDRRKIYRWFDPIIWTCLPLLYFGFALINGLLLKWQIPGTADSPFPYFFINMNKYGAQQVLINALVIALLYLLFGYILLGIKQMIGQKRQVTDNSSLNMS
>NZ_CP044493.1|WP_151416351.1|1280357_1281998_-|phosphoenolpyruvate-carboxykinase-(ATP)
MVTRQHFSEDSMRKNNSYFSALKATIETAFYENHVVPLKELAEAYRLAAKSPNTIVLDTPVAHAEDLGLPKDAKILLENSGGIVGRTAKARRIFGQDSKEDAKILQIIREAIFQARHRTFYRADAVVGLDEAFMLRAHLMVPQDDINNLYSWLNNFQVLNDTYRERLKKSKRYEETDIYIFSDPEWSHPDYPDGLVYFDTNHNCAAILGLHYFGELKKATLTLAWGTANRNKYVACHGGLKIFEKEGQKPYVASFFGLSGSGKSTLTHAKHNGKYRIDVLHDDAFVISEEDGSTIALEPAYFDKTNDYPAGHREQKYFVAVQNCGAALDKEGHLRLVTEDIRNGNGRTIKSRFSTPNRVDRINHPIQSIFWIMKDDSLPPLIRVTDPIMASIMGCTLVTTRSTAENTTDSLDALIIEPYANPFRVYPLVEDYIKFQHLFESGVNCYIINTGSYLGQDIPKEATLDVIEQVVDGTAKFESFGSVKGFEYLSSSHYKISNFDKAYVKIIRQRMKIRLQYLEAFNRKNPKLSLPDEAISHLKDVLANLG
>NZ_CP044493.1|WP_151416350.1|1279082_1280165_+|DEAD/DEAH-box-helicase
MKTQFPSVWQDKLSQKHFSAFTTIQEAAFDPIKNGKSLLGISPTGSGKTLAYLWPSLLTLTPKKAQQLLILAPNTELAGQIFEVAKEWAQPLNLTAQLFLSGSSQKRQIERLKKGPEIIIGTPGRVFDLVKLKKIKMMNVNTIVLDEFDDLLGKSQIHFVENIVKRVPRDHQMIYMSATNSIDRTFLADDTLEIDLSKQTVDTISHYYITVAKRERGELLRKFSNIPNFRGLVFFNRLSDLGANEERLQFSGASAISLASDVNIKFRKVILEKFKNHELSLLLATDLVARGIDIELLETVINFDLPKDKDAYNHRAGRTGRMGKNGIVVTFISHPEELKKLKKFAHVSEVYLKNQILHKK
>NZ_CP044493.1|WP_151416354.1|1291783_1292833_-|CRISPR-associated-protein-Cas7
MKLHFSHPYKDNLEINFGAFTQVVGQNQQLKYYIWQLLIWYFDGKKYREEDLTLFNQAEPEISDGNQPIKRNTFKIISISDIQELLEQMTYKKGTVSFDFMRQKLNDINIMTDIDDMNDRLSSISSKINDKLALSIQDINYHTESIDFNAEQLLLKNFIPFFEFQHQNISFEFVDNEGKILFFLEMLEETLTTTTGKILLVLKNMDDYLTYPSFILACQKLERLCMKFPYFQVIIFPSNEGYLYARQNNIEYVNIISDYVAHYYQFDFLFNRFIEQYPTNQLPTKADFLSSIQKISSYLFSKEIEYVSLSNKDLVTIKILNNLYQYDKKINYPILDSSPLEIKFLRDND
>NZ_CP044493.1|WP_002299167.1|1292829_1293153_-|CRISPR-associated-endonuclease-Cas2
MRYEAMRLLCFFDLPMETVQEKRTYRNFRKELIANGFEMLQFSVYYRTCPNRSFAKKFYKRLELASLPAGNVRLLAVTEKQFSEMILIVGGKTRQEEVISDNKLVII
>NZ_CP044493.1|WP_151416355.1|1293155_1294064_-|type-II-CRISPR-associated-endonuclease-Cas1
MTWRIVHVKQSEKMRLKLDNLVIKKLGEEFTIPLSDISMIVAEGGDTVVTLRLLSALSKYNISLIVCDNEHLPTGIYHAQNGHFRAYKKLQQQLLWTQNQKDILWQIVTYFKINNQQDVLAMLEKDLSAIQLLSEYKENIELGDKTNREGHAAKVYFNELFGKQFVRITQQESDIINAGLNYGYAIIRAQLARIVAGYGLNPLIGIFHKNEYNQFNLVDDLMEPFRQIIDVWVYTNLRDKDYLKYEHRLNITNLLNAKIKYGKEMCMVTGAMDKYVKGFIKCIDKEDSSRFYCPVISSLEME
>NZ_CP044493.1|WP_151416356.1|1294232_1297610_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTNGKILGLDIGIASVGVGIINAKTGNVEHASSRIFPAANADNNVERRSARGGRRLIRRKKHRLKRVEDLFEKYNIDTDFSNLNLNPYQLRVKGLNEQLSNEELFAILKNIAKRRGISYLDDAEDDSVGSSDYAKAIDENRKLLKKQTPGEIQLKRLEKYGQLRGNFTIQDENGEYHRLINVFSTSDYVKEARRILETQSYYNKFITESFVEDYIKILQGKRKYYVGPGNEKSRTDYGIYRTDGETLDNLFGILIGKCGFYPEEYRAAKASYTAQEYNFLNDLNNLTVPTETKKLSTEQKYQLVDFAKTASTLEAAKLLKEIAKLVGCQVEEIKGYRLDNKDKPDLHTFEPFRKLKSNLTTIAVENLSITTLDTLAHILTLNTEREGIEEAIQKELPNIFSDEQITEIIAVRKKNSQIFGKGWHSFSIKLMKELIPELYETSEEQMTILIRLKKVKTNSKITNRTKYINEQEVTDEIYNPVVSKSIRQTVKIINAAIKKYGAFDQIVIEMPRESNEEDERKFIADLQKSNAKEKDDAMKQAALLYNGKAELPHGVFHGHKELATKIRLWYQQGERCLYSGKHIDIHDLIHNQHMFEIDHVLPLSLSFDDSLANKVLVYSWANQEKGQRTPFQALPQMASAWSFRELRDYISKQKGISKKKRDYLLTEQDINKVEVKQKFIERNLVDTRYVSRVVLNTLQDALKVMNKETKISVIRGQFTSQLRRQWRIDKSRETYHHHAVDALIIAASSQLRLWKKQNNPMFAEDKHGQKINLDTGEVLSDDAYKELVYQAPYQGFVNTISSKSFEDEILFSYQVDSKVNRKISDATIYATRQAQLGKDKKEETYVLGKIKDIYSQAGYDAFRKKYDKDKAVFLMYQKDPETWEKVIEVILRDYKELDDKGKEIGNPFERYKVKHGFVRKYSRKNKGTEIKSLKYYDNKLGNHIDITPNNSKHSVVLQSINPWRADLYFNPETTKYELMGLKYADLSFEKGTGKYSISREKYDEIKEREGISSKSEFKFTLYKNDLILVKDIGNHKELIARFNSKNDTSKHYVELKPWNKAKFDSEEELIPAFGKVAKSGQFIKGLNKPDLSIYKVKTDILGHKYYIKKEGDKPKLNFENKIKNK
>NZ_CP044493.1|WP_151416357.1|1297828_1298704_-|NAD(P)H-dependent-oxidoreductase
MKLVAIVGSNASFSYNRLLLQFIKERFGQAFALEILEIKELPLFNQDSSAADCPLIQKLNEDILNADGIIIATAEHNQTITASLKSMLEWLSYQLHPFKNKPVMIVGASYYNQGTSHAQEHLRQILNAPGLDAWVMPGNEFFLGNASEVFDENNQIKDDDTVIYLVQCLQRFIRYVTVVQELKGDSIQLSDAISGASESVQEDSAASAMLEKQLSLQKKETNTPFERALDKTYGPALKDTLEDPFDKVLDAQYKAIKKQPIPFEKALDNIFGKDLGIETTDPLGNLLRSEQ
>NZ_CP044493.1|WP_032538907.1|1298811_1299690_-|helix-turn-helix-transcriptional-regulator
MVRFISNTLSQTLNEPFQQSHKSCKHLYILEILSQVVIVSDQKQVPLQPYDIILAQSFNHLQIDSLDRNPILLRLYSLDFDLPSPLNQYTVGDNPLIHDLMNDHTSEDAYILFTNLSDLICHAYLDALEKLENLRDNNDEQVYINFQRQKLAGLLFTELLRQHDAKVSKFASRFPSVNVKYASKDSQSGAIMKYVSDNVHHISLKEAAAHFSYQANYFSRLCHELFGISFNQLKTTIRLEIAKEQLRLTTKSVEEISQELGYKAVSNFHRNFKSQTGMTPNDYRQDKQWKDT
>NZ_CP044493.1|WP_151416358.1|1299814_1301305_+|FAD-dependent-oxidoreductase
MEKEYKVDVVVAGAGGAGLAAAHAAAQNGLKVLVLEKLKQIGGNTRISSGFFAINTKEQNAAGLKLSTQEAIRQLQEHNHFLSNGALLKNIIEHAKETLEEIEKLGMEIKLNPTKNSTQFAHFGNDYQGGSYHMYMNKDSSYLQIQKSLEAMGVTFIFGVRMTELLQDSNGHVRGLKALNDAGESMTVHAKASIIATGGFGGDKRRVAKVMRTLNLRTLGVPNMGEGLSAMEAAGGVNIDGSALIHAAQMAQSTVTQETKVKQLAGFNDSPLTQLLLSPLLWVDPNGSRFTNEDVVYDTVQWSNAAYGVGSKYYYVMDTATLESYTKQPLLTISKSGPGASQAKGDFVSLAEQAVQQGIAFKGDSLEELAQNSGMDPIAFKATVAEYNKAIASQNDEIFSKSASSLKYDVKKGPFYAFIAQVVYLGTVGGVRVDKDLRVLDAYMKAIPGLYTGGANAGGYYAPRNYPAYEGLASGFSWTSGRLAGLAAANDIKKYN
>NZ_CP044493.1|WP_002279852.1|1301314_1302490_+|MFS-transporter
MNQKNLSPSSWFFKISVLSLSILAMTAPSISIANNLLQKTFTQQSTAEIEMISTLPNFGVLLLILFADTIANKFGIKRTIMAGLLMYLLGGVLPSFIPNYYAIVFLRFLMGCGIGLFNPFSVSLMYRFYKDQELSDMLGFQNTGQNLGNAGFGFLLGALVLAGWKVAFMGYFIALIPLILFGAFVVIPDDQPTIKKERPKLADSINGHILLLALLFLIIFGMFMMMTIKMALFGAETGLISASAASSILAVLGLSSMFSAIAFGKLSKRVGNFMLPISLTGIAMGFFIVASASNAAMVVLGVIIAGIFFGWVFPQAFLRAAQVGPKEGGTLTTSVILMGINLGAFLSPSVVNFVANLLGNKTAASVLAMCGWGFALLAILEYLYTFFNQRT
>NZ_CP044493.1|WP_151416359.1|1302665_1305194_-|ATP-binding-cassette-domain-containing-protein
MLELKHITKVYETAGIKRMALENVSVNFRANEFVAVLGQSGSGKTTLLNIIGGLDQYTTGDLLINGKSTKDFKDKDWDSYRNNTIGFVFQSYNLISHQTALANVELALTLSGVSKAERRKRALDALKRVGLEDEINKKPNQMSGGQMQRVAIARALVNNPDILLADEPTGALDSETSLQIMDLLKEIAQERLVIMVTHNPDLAEKYSNRIIKVLDGHIINDSNPYTDDEIRKATVDFKKTKMSFTTALSLSFNNLLTKKGRTLLTAFAGSIGIIGITLILSLSNGVQKYIAKTQEDTLVAYPLSIEKSSNKNFIGLLAANSNENKKSDKKKTNKKIGTNSILKNMISTQVVDNDLASFKTYIKKHQKKFAAVTKDIQYSYKITPRIYQPDTSKGVKAVNPNTLSKDLKDTSTSIQTVVSNLDIWQELSSNEKMLSSQYQVISGHLPKQYNEVVLMADENNKIDDYVLYSLGIKDAKQLNSKTIKKVKASSYHYKDLIGRTYKLVINSDLYQKEGNAWIDRSDNDAYMKQVINAAENIKIVGIVKPQEGTTSESSSAGVGYSHDLTDYLAKKIKSSTIAKEQLANKKLNVFTGQSFSSGNKTFSSDNLSVQQQASMASMSAEELADYVNRYNENANATYKDNLEKIGIIDNNNPETIHFYASSFKDKEALKDLISDYNKKVKRDKHKSRVIRYTDTVGLMMSSVTTMINAVTYILIGFVAISLIVSSIMIGIITYISVLERTKEIGVLRAMGASKKDVTRIFTAETIIEGAIAGVLGILITLLLNIAITLIVKNWLNINHISSLPIWSAIVLIAISIVLTVFAGILPSRVAAKKDPVEALRTE
>NZ_CP044493.1|WP_151416360.1|1305936_1306710_-|TIGR01457-family-HAD-type-hydrolase
MTYKGYLIDLDGTIYKGKDRIPAGEDFVKRLQERQLPYILVTNNTTRTPEMVQEMLATSFNIKTPLETIYTATLATIDYMNDMKRGKTAYVIGETGLKKAVAEAGYREDSENPAYVVVGLDTNLTYEKLTLATLAIQKGAVFIGTNPDLNIPTEHGLLPGAGAILFLLEKATRVKPIIIGKPEAVIMNKALDRLGVKRHEAIMVGDNYLTDITAGIKNDIATLLVTTGFTKPEEVPALPIQPDFVLSSLAEWDFDER

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Crispr_ID: NZ_CP044493_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044493_2

1393258-1395971

TypeI-E

Consensus_repeat	Method
GGATCACCCCCGCTCGTGCGGGTAAAAT	PILER-CR
GGATCACCCCCGCTCGTGCGGGTAAAAT	CRISPRCasFinder
GGATCACCCCCGCTCGTGCGGGTAAAAT	CRT
GGATCACCCCCGCTCGTGCGGGTAAAAT	PILER-CR

44 spacers

DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,WYL

The CRISPR arrays of NZ_CP044493_2

>merge|NZ_CP044493|2|1393258-1395971|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GGATCACCCCCGCTCGTGCGGGTAAAATTTTCTGTAACAACAGAGACGCAGCTTCAGGGTAGGATCACCCCCGCTCGTGCGGGTAAAATTTAAGTAGAATCTATGAGTTAGCCAACAATCCAGGATCACCCCCGCTCGTGCGGGTAAAATTATTGCATAATCATTTAGCGGAACAAATTTATGGGATCACCCCCGCTCGTGCGGGTAAAATGATGGTCTTGCCAAACCACGGATAAGAGCCGTGGGATCACCCCCGCTCGTGCGGGTAAAATTACAATAGATTATTCAAATTCTGTGTATTTTGGGGATCACCCCCGCTCGTGCGGGTAAAATCAGAGAACGAGCATACATATGATAATTAAACTAGGATCACCCCCGCTCGTGCGGGTAAAATGTTGCTACTATGGCATCAGAATATATTGTTGTAGGATCACCCCCGCTCGTGCGGGTAAAATCAAAAAGATACACTCTATTTAATTGAAGAAGTAGGATCACCCCCGCTCGTGCGGGTAAAATTCTCAGACATTGATGCACCTAAATTAGTTATTGGGATCACCCCCGCTCGTGCGGGTAAAATGCACATAGTCACAGAAAACGGGGAAATTCCCTAGGATCACCCCCGCTCGTGCGGGTAAAATGATGGAAGTAGAGCGCTTGACTAGACAACGGCAGGATCACCCCCGCTCGTGCGGGTAAAATGCGGGATTACTGATTACACTATCGCAGAAGATGGGGATCACCCCCGCTCGTGCGGGTAAAATTAGCGTTATCGGCAGACTAGCCTTATATATATAGGATCACCCCCGCTCGTGCGGGTAAAATTCGCCGGGGTCAAATACCTTTTTGACCATGCCGGGATCACCCCCGCTCGTGCGGGTAAAATGCTTCTTCCTAAGCACACTAGCAAAGATGGATAGGATCACCCCCGCTCGTGCGGGTAAAATGAGCGCAAAGCGGAGCAAAAGAAGCAGAAGTTGGGATCACCCCCGCTCGTGCGGGTAAAATGCCACAATTCACTCTTACGAATCTTATTGTACAGGATCACCCCCGCTCGTGCGGGTAAAATAAAGCTGTTAAAGAAGCCTGTTCCTGAAGCGTAGGATCACCCCCGCTCGTGCGGGTAAAATAATAACAAACAACACAACGCAGCTAAGCTATCGGGATCACCCCCGCTCGTGCGGGTAAAATCAGCAGAACAGCGTGCAAGAAACGCAAGCGGAAGGGATCACCCCCGCTCGTGCGGGTAAAATAGAGCATAACTAATCCGACAACAATCACAGTTGGGATCACCCCCGCTCGTGCGGGTAAAATATGAAAATTAAAACAGGAGACATTTAATTAGCGGGATCACCCCCGCTCGTGCGGGTAAAATTAACACGTAACATTTTTAGTGTCATTTTTTTCAGGATCACCCCCGCTCGTGCGGGTAAAATGATATGAATTATATCTTCTTGTTCCAAATGCCAGGATCACCCCCGCTCGTGCGGGTAAAATGTATACTTTACTCCTAAATCAGAAACAATTTTAGGATCACCCCCGCTCGTGCGGGTAAAATTTTATGGCCATGATTTTGGTCATACGGGCTATAGGATCACCCCCGCTCGTGCGGGTAAAATAATTATTGAATACTAAAATAATTGATTGAAATGGGATCACCCCCGCTCGTGCGGGTAAAATGCTAACAATTGGACATTTTTCGGCGGTTATCCAGGATCACCCCCGCTCGTGCGGGTAAAATGTGTACAATTGTTAGAGAGTTATGCTGAACGTGGGATCACCCCCGCTCGTGCGGGTAAAATTGATATTAATGCGGTTTTTAACTCCCTTGAGAGGGATCACCCCCGCTCGTGCGGGTAAAATGTTTATGCAGGGGGGGGCTTAGATGGCTAACAAGGATCACCCCCGCTCGTGCGGGTAAAATCAGTAGTTTTCCGTTTTGGTCTGAAAACAGGAGGGATCACCCCCGCTCGTGCGGGTAAAATGAAGAAAAATAAGGCAGTCTTCTTTGCTGGAAAGGATCACCCCCGCTCGTGCGGGTAAAATTTTGAAAATCCTGCTGTACAGTCGTTTTCCGTAGGATCACCCCCGCTCGTGCGGGTAAAATAAGCAGACGTGCTAATCTCTGCAAAATCTGATAGGATCACCCCCGCTCGTGCGGGTAAAATGCCGGATAACCACAACTCCACTTTCAAACGGTAGGATCACCCCCGCTCGTGCGGGTAAAATTACAAGAACGCTACCGAAAACTTCGCTCAAACAGGATCACCCCCGCTCGTGCGGGTAAAATTAAAAAACGTTTCTCAAGAAAACATTAATAATAGGATCACCCCCGCTCGTGCGGGTAAAATATCTGTCAATGGGAGCAGATGACGAAGGTTTTAGGATCACCCCCGCTCGTGCGGGTAAAATGTTACGATAATCTGTTAGCAGCCATCAATTACAGGATCACCCCCGCTCGTGCGGGTAAAATGGAACGTTTGCAGGGAATGTTATTTCTAGCGCAGGATCACCCCCGCTCGTGCGGGTAAAATACTGCAACTGACATTGTCTTGATTTTAGGACTAGGATCACCCCCGCTCGTGCGGGTAAAATAGCAATCGAAAAAGCGCCTGTTGAAATTAAGCGGGATCACCCCCGCTCGTGCGGGTAAAATTTGCGTATTATCCATTTGTGCTAACGCAATTTGGGATCACCCCCGCTCGTGCGGGTAAAAT

>NZ_CP044493|2|2|1393258-1394445|PILER-CR
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTCTGTAACAACAGAGACGCAGCTTCAGGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTAAGTAGAATCTATGAGTTAGCCAACAATCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TATTGCATAATCATTTAGCGGAACAAATTTATG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGTCTTGCCAAACCACGGATAAGAGCCGTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAATAGATTATTCAAATTCTGTGTATTTTGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGAGAACGAGCATACATATGATAATTAAACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTGCTACTATGGCATCAGAATATATTGTTGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAAAAAGATACACTCTATTTAATTGAAGAAGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCTCAGACATTGATGCACCTAAATTAGTTATTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCACATAGTCACAGAAAACGGGGAAATTCCCTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGAAGTAGAGCGCTTGACTAGACAACGGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCGGGATTACTGATTACACTATCGCAGAAGATGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAGCGTTATCGGCAGACTAGCCTTATATATATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCGCCGGGGTCAAATACCTTTTTGACCATGCCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCTTCTTCCTAAGCACACTAGCAAAGATGGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAGCGCAAAGCGGAGCAAAAGAAGCAGAAGTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCACAATTCACTCTTACGAATCTTATTGTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAAGCTGTTAAAGAAGCCTGTTCCTGAAGCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AATAACAAACAACACAACGCAGCTAAGCTATCG
GGATCACCCCCGCTCGTGCGGGTAAAATCAGCAGAACAGCGTGCAAGAAACGCAAGCGGAAGGGATCACCCCCGCTCGTGCGGGTAAAATAGAGCATAACTAATCCGACAACAATCACAGTTGGGATCACCCCCGCTCGTGCGGGTAAAATATGAAAATTAAAACAGGAGACATTTAATTAGCGGGATCACCCCCGCTCGTGCGGGTAAAATTAACACGTAACATTTTTAGTGTCATTTTTTTCAGGATCACCCCCGCTCGTGCGGGTAAAATGATATGAATTATATCTTCTTGTTCCAAATGCCAGGATCACCCCCGCTCGTGCGGGTAAAATGTATACTTTACTCCTAAATCAGAAACAATTTTAGGATCACCCCCGCTCGTGCGGGTAAAATTTTATGGCCATGATTTTGGTCATACGGGCTATAGGATCACCCCCGCTCGTGCGGGTAAAATAATTATTGAATACTAAAATAATTGATTGAAATGGGATCACCCCCGCTCGTGCGGGTAAAATGCTAACAATTGGACATTTTTCGGCGGTTATCCAGGATCACCCCCGCTCGTGCGGGTAAAATGTGTACAATTGTTAGAGAGTTATGCTGAACGTGGGATCACCCCCGCTCGTGCGGGTAAAATTGATATTAATGCGGTTTTTAACTCCCTTGAGAGGGATCACCCCCGCTCGTGCGGGTAAAATGTTTATGCAGGGGGGGGCTTAGATGGCTAACAAGGATCACCCCCGCTCGTGCGGGTAAAAT	CAGTAGTTTTCCGTTTTGGTCTGAAAACAGGAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAAGAAAAATAAGGCAGTCTTCTTTGCTGGAAA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTGAAAATCCTGCTGTACAGTCGTTTTCCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAGCAGACGTGCTAATCTCTGCAAAATCTGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCGGATAACCACAACTCCACTTTCAAACGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAAGAACGCTACCGAAAACTTCGCTCAAACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAAAAAACGTTTCTCAAGAAAACATTAATAATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ATCTGTCAATGGGAGCAGATGACGAAGGTTTTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTACGATAATCTGTTAGCAGCCATCAATTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GGAACGTTTGCAGGGAATGTTATTTCTAGCGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ACTGCAACTGACATTGTCTTGATTTTAGGACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AGCAATCGAAAAAGCGCCTGTTGAAATTAAGCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTGCGTATTATCCATTTGTGCTAACGCAATTTG


>NZ_CP044493|2|2|1393258-1395971|CRISPRCasFinder
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTCTGTAACAACAGAGACGCAGCTTCAGGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTAAGTAGAATCTATGAGTTAGCCAACAATCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TATTGCATAATCATTTAGCGGAACAAATTTATG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGTCTTGCCAAACCACGGATAAGAGCCGTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAATAGATTATTCAAATTCTGTGTATTTTGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGAGAACGAGCATACATATGATAATTAAACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTGCTACTATGGCATCAGAATATATTGTTGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAAAAAGATACACTCTATTTAATTGAAGAAGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCTCAGACATTGATGCACCTAAATTAGTTATTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCACATAGTCACAGAAAACGGGGAAATTCCCTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGAAGTAGAGCGCTTGACTAGACAACGGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCGGGATTACTGATTACACTATCGCAGAAGATGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAGCGTTATCGGCAGACTAGCCTTATATATATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCGCCGGGGTCAAATACCTTTTTGACCATGCCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCTTCTTCCTAAGCACACTAGCAAAGATGGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAGCGCAAAGCGGAGCAAAAGAAGCAGAAGTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCACAATTCACTCTTACGAATCTTATTGTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAAGCTGTTAAAGAAGCCTGTTCCTGAAGCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AATAACAAACAACACAACGCAGCTAAGCTATCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGCAGAACAGCGTGCAAGAAACGCAAGCGGAAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	AGAGCATAACTAATCCGACAACAATCACAGTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	ATGAAAATTAAAACAGGAGACATTTAATTAGCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAACACGTAACATTTTTAGTGTCATTTTTTTCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATATGAATTATATCTTCTTGTTCCAAATGCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTATACTTTACTCCTAAATCAGAAACAATTTTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTATGGCCATGATTTTGGTCATACGGGCTATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AATTATTGAATACTAAAATAATTGATTGAAATG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCTAACAATTGGACATTTTTCGGCGGTTATCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTGTACAATTGTTAGAGAGTTATGCTGAACGTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TGATATTAATGCGGTTTTTAACTCCCTTGAGAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTTATGCAGGGGGGGGCTTAGATGGCTAACAA
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGTAGTTTTCCGTTTTGGTCTGAAAACAGGAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAAGAAAAATAAGGCAGTCTTCTTTGCTGGAAA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTGAAAATCCTGCTGTACAGTCGTTTTCCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAGCAGACGTGCTAATCTCTGCAAAATCTGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCGGATAACCACAACTCCACTTTCAAACGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAAGAACGCTACCGAAAACTTCGCTCAAACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAAAAAACGTTTCTCAAGAAAACATTAATAATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ATCTGTCAATGGGAGCAGATGACGAAGGTTTTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTACGATAATCTGTTAGCAGCCATCAATTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GGAACGTTTGCAGGGAATGTTATTTCTAGCGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ACTGCAACTGACATTGTCTTGATTTTAGGACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AGCAATCGAAAAAGCGCCTGTTGAAATTAAGCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTGCGTATTATCCATTTGTGCTAACGCAATTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT

>NZ_CP044493|2|2|1393258-1395971|CRT
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTCTGTAACAACAGAGACGCAGCTTCAGGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTAAGTAGAATCTATGAGTTAGCCAACAATCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TATTGCATAATCATTTAGCGGAACAAATTTATG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGTCTTGCCAAACCACGGATAAGAGCCGTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAATAGATTATTCAAATTCTGTGTATTTTGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGAGAACGAGCATACATATGATAATTAAACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTGCTACTATGGCATCAGAATATATTGTTGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAAAAAGATACACTCTATTTAATTGAAGAAGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCTCAGACATTGATGCACCTAAATTAGTTATTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCACATAGTCACAGAAAACGGGGAAATTCCCTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGAAGTAGAGCGCTTGACTAGACAACGGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCGGGATTACTGATTACACTATCGCAGAAGATGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAGCGTTATCGGCAGACTAGCCTTATATATATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCGCCGGGGTCAAATACCTTTTTGACCATGCCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCTTCTTCCTAAGCACACTAGCAAAGATGGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAGCGCAAAGCGGAGCAAAAGAAGCAGAAGTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCACAATTCACTCTTACGAATCTTATTGTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAAGCTGTTAAAGAAGCCTGTTCCTGAAGCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AATAACAAACAACACAACGCAGCTAAGCTATCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGCAGAACAGCGTGCAAGAAACGCAAGCGGAAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	AGAGCATAACTAATCCGACAACAATCACAGTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	ATGAAAATTAAAACAGGAGACATTTAATTAGCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAACACGTAACATTTTTAGTGTCATTTTTTTCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATATGAATTATATCTTCTTGTTCCAAATGCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTATACTTTACTCCTAAATCAGAAACAATTTTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTATGGCCATGATTTTGGTCATACGGGCTATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AATTATTGAATACTAAAATAATTGATTGAAATG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCTAACAATTGGACATTTTTCGGCGGTTATCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTGTACAATTGTTAGAGAGTTATGCTGAACGTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TGATATTAATGCGGTTTTTAACTCCCTTGAGAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTTATGCAGGGGGGGGCTTAGATGGCTAACAA
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGTAGTTTTCCGTTTTGGTCTGAAAACAGGAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAAGAAAAATAAGGCAGTCTTCTTTGCTGGAAA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTGAAAATCCTGCTGTACAGTCGTTTTCCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAGCAGACGTGCTAATCTCTGCAAAATCTGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCGGATAACCACAACTCCACTTTCAAACGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAAGAACGCTACCGAAAACTTCGCTCAAACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAAAAAACGTTTCTCAAGAAAACATTAATAATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ATCTGTCAATGGGAGCAGATGACGAAGGTTTTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTACGATAATCTGTTAGCAGCCATCAATTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GGAACGTTTGCAGGGAATGTTATTTCTAGCGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ACTGCAACTGACATTGTCTTGATTTTAGGACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AGCAATCGAAAAAGCGCCTGTTGAAATTAAGCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTGCGTATTATCCATTTGTGCTAACGCAATTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT

>NZ_CP044493|2|3|1395151-1395971|PILER-CR
	TTTCTGTAACAACAGAGACGCAGCTTCAGGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTAAGTAGAATCTATGAGTTAGCCAACAATCCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TATTGCATAATCATTTAGCGGAACAAATTTATG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGTCTTGCCAAACCACGGATAAGAGCCGTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAATAGATTATTCAAATTCTGTGTATTTTGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAGAGAACGAGCATACATATGATAATTAAACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTGCTACTATGGCATCAGAATATATTGTTGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	CAAAAAGATACACTCTATTTAATTGAAGAAGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCTCAGACATTGATGCACCTAAATTAGTTATTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCACATAGTCACAGAAAACGGGGAAATTCCCTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GATGGAAGTAGAGCGCTTGACTAGACAACGGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCGGGATTACTGATTACACTATCGCAGAAGATGG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAGCGTTATCGGCAGACTAGCCTTATATATATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TCGCCGGGGTCAAATACCTTTTTGACCATGCCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCTTCTTCCTAAGCACACTAGCAAAGATGGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAGCGCAAAGCGGAGCAAAAGAAGCAGAAGTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCACAATTCACTCTTACGAATCTTATTGTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAAGCTGTTAAAGAAGCCTGTTCCTGAAGCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AATAACAAACAACACAACGCAGCTAAGCTATCG
GGATCACCCCCGCTCGTGCGGGTAAAATCAGCAGAACAGCGTGCAAGAAACGCAAGCGGAAGGGATCACCCCCGCTCGTGCGGGTAAAATAGAGCATAACTAATCCGACAACAATCACAGTTGGGATCACCCCCGCTCGTGCGGGTAAAATATGAAAATTAAAACAGGAGACATTTAATTAGCGGGATCACCCCCGCTCGTGCGGGTAAAATTAACACGTAACATTTTTAGTGTCATTTTTTTCAGGATCACCCCCGCTCGTGCGGGTAAAATGATATGAATTATATCTTCTTGTTCCAAATGCCAGGATCACCCCCGCTCGTGCGGGTAAAATGTATACTTTACTCCTAAATCAGAAACAATTTTAGGATCACCCCCGCTCGTGCGGGTAAAATTTTATGGCCATGATTTTGGTCATACGGGCTATAGGATCACCCCCGCTCGTGCGGGTAAAATAATTATTGAATACTAAAATAATTGATTGAAATGGGATCACCCCCGCTCGTGCGGGTAAAATGCTAACAATTGGACATTTTTCGGCGGTTATCCAGGATCACCCCCGCTCGTGCGGGTAAAATGTGTACAATTGTTAGAGAGTTATGCTGAACGTGGGATCACCCCCGCTCGTGCGGGTAAAATTGATATTAATGCGGTTTTTAACTCCCTTGAGAGGGATCACCCCCGCTCGTGCGGGTAAAATGTTTATGCAGGGGGGGGCTTAGATGGCTAACAAGGATCACCCCCGCTCGTGCGGGTAAAAT	CAGTAGTTTTCCGTTTTGGTCTGAAAACAGGAG
GGATCACCCCCGCTCGTGCGGGTAAAAT	GAAGAAAAATAAGGCAGTCTTCTTTGCTGGAAA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTTGAAAATCCTGCTGTACAGTCGTTTTCCGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AAGCAGACGTGCTAATCTCTGCAAAATCTGATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GCCGGATAACCACAACTCCACTTTCAAACGGTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TACAAGAACGCTACCGAAAACTTCGCTCAAACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	TAAAAAACGTTTCTCAAGAAAACATTAATAATA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ATCTGTCAATGGGAGCAGATGACGAAGGTTTTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GTTACGATAATCTGTTAGCAGCCATCAATTACA
GGATCACCCCCGCTCGTGCGGGTAAAAT	GGAACGTTTGCAGGGAATGTTATTTCTAGCGCA
GGATCACCCCCGCTCGTGCGGGTAAAAT	ACTGCAACTGACATTGTCTTGATTTTAGGACTA
GGATCACCCCCGCTCGTGCGGGTAAAAT	AGCAATCGAAAAAGCGCCTGTTGAAATTAAGCG
GGATCACCCCCGCTCGTGCGGGTAAAAT	TTGCGTATTATCCATTTGTGCTAACGCAATTTG
GGATCACCCCCGCTCGTGCGGGTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044493.1\|WP_002268121.1\|1401016_1402699_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP044493.1\|WP_002273847.1\|1382885_1383818_-\|tagatose-6-phosphate-kinase	unknown	unknown	gnl\|CDD\|273515
NZ_CP044493.1\|WP_002263056.1\|1379310_1379625_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|129903
NZ_CP044493.1\|WP_002262464.1\|1383836_1384352_-\|galactose-6-phosphate-isomerase-subunit-LacB	unknown	unknown	gnl\|CDD\|181506
NZ_CP044493.1\|WP_002265225.1\|1385112_1385868_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP044493.1\|WP_002265219.1\|1376179_1377586_-\|6-phospho-beta-galactosidase	unknown	unknown	gnl\|CDD\|184102
NZ_CP044493.1\|WP_002262463.1\|1384377_1384806_-\|galactose-6-phosphate-isomerase-subunit-LacA	unknown	unknown	gnl\|CDD\|181505
NZ_CP044493.1\|WP_002273845.1\|1379668_1381069_-\|PTS-mannitol/fructose,-IIC-component	unknown	unknown	gnl\|CDD\|226298
NZ_CP044493.1\|WP_002268123.1\|1399210_1400431_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP044493.1\|WP_002268883.1\|1397841_1398489_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP044493.1\|WP_002268884.1\|1396898_1397840_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP044493.1\|WP_002268124.1\|1398488_1399205_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|187886
NZ_CP044493.1\|WP_002268122.1\|1400420_1401017_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP044493.1\|WP_002262921.1\|1407315_1407561_-\|membrane-protein	unknown	unknown	unknown
NZ_CP044493.1\|WP_002265223.1\|1381410_1381884_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|334031
NZ_CP044493.1\|WP_002268127.1\|1395994_1396897_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NZ_CP044493.1\|WP_002271176.1\|1402691_1405478_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP044493.1\|WP_002267326.1\|1405667_1406651_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP044493.1\|WP_002263057.1\|1377597_1379304_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273055
NZ_CP044493.1\|WP_002273846.1\|1381900_1382881_-\|tagatose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|183502

Protein	Function_ID	Function_description	E-value
NZ_CP044493.1\|WP_002268121.1\|1401016_1402699_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.78806e-85
NZ_CP044493.1\|WP_002273847.1\|1382885_1383818_-\|tagatose-6-phosphate-kinase	gnl\|CDD\|273515	TIGR01231, Tagatose-6-phosphate_kinase, tagatose-6-phosphate kinase. This enzyme is part of the tagatose-6-phosphate pathway of lactose degradation. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP044493.1\|WP_002263056.1\|1379310_1379625_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|129903	TIGR00823, PTS_system_lactose-specific_IIA_component, phosphotransferase system enzyme II, lactose-specific, factor III. The PTS Lactose-N,N?-Diacetylchitobiose-b-glucoside (Lac) Family (TC 4.A.3)Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains.The Lac family includes several sequenced lactose (b-galactoside) permeases of Gram-positive bacteria as well as the E. coli N,N?-diacetylchitobiose (Chb)permease which can transport aromatic b-glucosides and cellobiose as well as the chitin disaccharide, Chb, but only Chb induces expression of the chboperon. While the Lac permeases consist of two polypeptide chains (IIA and IICB), the Chb permease of E. coli consists of three (IIA, IIB and IIC). In B. subtilis, a PTS permease similar to the Chb permease of E. coli is believed to transport lichenan (a b-1,3;1,4 glucan) degradation products, oligosaccharides of 2-4 glucose units. This model is specific for the IIA subunit of the Lac PTS family. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	9.66453e-45
NZ_CP044493.1\|WP_002262464.1\|1383836_1384352_-\|galactose-6-phosphate-isomerase-subunit-LacB	gnl\|CDD\|181506	PRK08622, PRK08622, galactose-6-phosphate isomerase subunit LacB; Reviewed.	8.58673e-124
NZ_CP044493.1\|WP_002265225.1\|1385112_1385868_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.81514e-78
NZ_CP044493.1\|WP_002265219.1\|1376179_1377586_-\|6-phospho-beta-galactosidase	gnl\|CDD\|184102	PRK13511, PRK13511, 6-phospho-beta-galactosidase; Provisional.	0
NZ_CP044493.1\|WP_002262463.1\|1384377_1384806_-\|galactose-6-phosphate-isomerase-subunit-LacA	gnl\|CDD\|181505	PRK08621, PRK08621, galactose-6-phosphate isomerase subunit LacA; Reviewed.	3.84241e-90
NZ_CP044493.1\|WP_002273845.1\|1379668_1381069_-\|PTS-mannitol/fructose,-IIC-component	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	1.97445e-161
NZ_CP044493.1\|WP_002268123.1\|1399210_1400431_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	6.15499e-145
NZ_CP044493.1\|WP_002268883.1\|1397841_1398489_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	3.65948e-69
NZ_CP044493.1\|WP_002268884.1\|1396898_1397840_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	8.18423e-132
NZ_CP044493.1\|WP_002268124.1\|1398488_1399205_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.34468e-43
NZ_CP044493.1\|WP_002268122.1\|1400420_1401017_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.86292e-38
NZ_CP044493.1\|WP_002265223.1\|1381410_1381884_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|334031	pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.	5.06366e-24
NZ_CP044493.1\|WP_002268127.1\|1395994_1396897_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	1.6238e-41
NZ_CP044493.1\|WP_002271176.1\|1402691_1405478_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	5.93834e-95
NZ_CP044493.1\|WP_002267326.1\|1405667_1406651_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	9.10188e-10
NZ_CP044493.1\|WP_002263057.1\|1377597_1379304_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273055	TIGR00394, lac_pts_IIC, phosphotransferase system, lactose specific, IIC component. This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	0
NZ_CP044493.1\|WP_002273846.1\|1381900_1382881_-\|tagatose-bisphosphate-aldolase	gnl\|CDD\|183502	PRK12399, PRK12399, tagatose 1,6-diphosphate aldolase; Reviewed.	0

>NZ_CP044493.1|WP_002265225.1|1385112_1385868_-|DeoR/GlpR-transcriptional-regulator
MKKEERLEEITKLINKRGTIRVTEVVERLKVSDMTVRRDLTELEGLGVLTRIHGGARSNNIFQYKEMSHEEKHSRQIEEKHYIAQKAAELVEEGDTIFLGPGTTVELLAEEINKTTLQVITNCLPVFQILSQKQSETFRVHLLGGEMRSITQSFIGEITNIVLEKMHFSKMFFSGNGVKGNEVMTSSFQEAYTQKMALGRAIEKYLLIDSSKIGKEDFTSFYQLSQLTALITDCQDDDKLQKLSKYTEIIN
>NZ_CP044493.1|WP_002262463.1|1384377_1384806_-|galactose-6-phosphate-isomerase-subunit-LacA
MAIIIGSDAAGKRLKDVIKTFLKDNNHEVLDVTERKDLDFVDSTLAVVHEVQKNDKNLGIAIDAYGAGSFMVATKVKGMIAAEVSDERSAYMTRGHNNARIITLGAEIVGDELAKNIVKDFVEAKYDGGRHQIRVDMLNKMC
>NZ_CP044493.1|WP_002262464.1|1383836_1384352_-|galactose-6-phosphate-isomerase-subunit-LacB
MKIAIGCDHIVTDVKMELSKHLKEEGYEVLDVGTYDFTRTHYPIFGKKVGEAVSSGEADLGVCMCGTGVGISNAANKVPGVRTALVRDMTSALYSKEELNANVVSFGGAIIGKLLLFDIVDAFIKAQYKPTEENKKLIAKIKHLEAHNDKQADPHFFDEFLEKWNRGDYHD
>NZ_CP044493.1|WP_002273847.1|1382885_1383818_-|tagatose-6-phosphate-kinase
MMLTVTMNPSIDIAYQLDDLKVDTVNRVIETHKTPGGKGLNVTRVLSQLGDDVLASGLLGGKLGEFLEAELDKSAIKHSFYKISAETRNCIAILHGGYQTEILEQGPYVSAKESKGFLEFFEKLLPKLEVVAISGSLPKGVPVDYYSQMIAICKQHQVPIVLDCSGQALLEVLNGAAKPTVIKPNTEELSQIMEREITNDVAVLKYALASPIFSGIDWIIVSLGSQGSFAKHGQTFYKVTIPKIAVVNPVGSGDSTVAGITSALAAGASDEKLLKKANTLGMLNAQEKLTGHVNLENYDNLYQQIEVAEV
>NZ_CP044493.1|WP_002273846.1|1381900_1382881_-|tagatose-bisphosphate-aldolase
MTLTQEKRSYMEKLSDENGIISALAFDQRGALKRLMAQYQTQEPTIAQMEELKVLVAEELTPYASSMLLDPEYGLPAAKHLDKNAGLLLAYEKTGYDTTSTKRLPDCLVEWSAKRLKKQGADAVKFLLYYDVDGDEEVNQQKQAYIERIGSECKAEDIPFFLEILAYDETITDAASVEYAKVKPHKVLDAMKVFSDERFGIDVLKVEVPVNMKYVEGFGDGPIVYTQDQAANFFKQQDQATPLPYIYLSAGVSAKLFQDTLVFAKESGANFNGVLCGRATWAGSVKDYIEKGEAAARQWLRTEGFKNIDELNKVLKATATSWEERA
>NZ_CP044493.1|WP_002265223.1|1381410_1381884_-|PTS-sugar-transporter-subunit-IIA
MSQLFSEDTVFISKQKEKEEVFKEIAGKLLERKLVTSEYINNLIEREKNYPTALSLSPIDTSLPNIAIPHTESEYVTETRIVPVKLKYPIVFHNMILPDEEVTVSFLFMILNHNESEQAGLLAGIMDFINRQSISDLKVFFNLEDSHKIFDYLKQHY
>NZ_CP044493.1|WP_002273845.1|1379668_1381069_-|PTS-mannitol/fructose,-IIC-component
MNVIIEFANAVFKPIIDLGAAPLMTVILTIIALCFRVKFTKALEGGIKLGIALTGISAIINILSTAFSGAMTDFVDRTGLHLNITDVGWAPLATITWGSPYTLYFLLVMLIVNIIMLVFHQTNTLDVDIFDIWHLSIVGLFAIFSGANLLVATVLVIFIGVLKIINSDVMKPTFNDLLGTGNENPMTTTHMNYMMNPIIMVFDKIFDKLFPWLDKYDFDAAKLNAKIGFWGSKFAIGVYLGIFVGLLAGQTPTQVISLAFTAAVCLELFSLIGSWFIAAVEPLSQGITNFASSKLKGRTLNIGLDWPFLAGRAEIWAAANILAPIMLFEAIILPGNKLLPLAGIIAMGVTPALLVVTRGKLIRMIIIGTIELPLFLWSGSLMAPFITETAKKVGAFPKGISSSTLISHTTMEGPIEKFLAYFAGKGTAGDVQYMLYAVIALAVYTLLFFWYVAQMKKRNQAYEEAK
>NZ_CP044493.1|WP_002263056.1|1379310_1379625_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MNREEATLLGFEIVAYAGDARSKLLEALNAAQAGEYDRAEELVAAADDCIVDAHKAQTSLLAKEAQGDDIELSVTLMHGQDHLMTTILLKDLMKHLIELYKRGS
>NZ_CP044493.1|WP_002263057.1|1377597_1379304_-|PTS-transporter-subunit-EIIC
MNTLIAQIEKGKPFFEKISRNIYLRAIRDGFISAMPVILFSSIFLLIAYVPNIFGFTWPKGIENMLMTPYNYTMGIIGFLVAGTTAKSLTDSMNRQLEKTNQINFISTMLASMAGFLIMAADPAKEGGFLSAFMGTKGLLTAFIAAFITVNVYKICVKNNVTIRMPEEVPPNISQVFKDIFPFAFSIIILYAIQLAIKAVIGVNVAQSIGTLLAPLFSAADGYLGITIIFGAYALFWFVGIHGPSIVEPAIAAITYSNVELNAHLIHAGQHADKVITSGTQMFIVTMGGTGATLVVPFMFMWLCKSKRNKAIGRASVVPTFFGVNEPILFGAPIVLNPVFFIPFILAPIVNVWIFKFFVDTLGMNSFFANLPWTTPGPIGIVLGTGFAVLSFVLAALLILVDTVIYYPFVKVYDEQILAEEAEGKSSSDALKEKVAANFDTKKADAILEGAESKEEPATHAITEETNVLVLCAGGGTSGLLANALNKAAEEYGAPVKAAAGSYGAHREILDQYQLVILAPQVASNYEDMKAETDKLGIKLAKTEGAQYIGLTRDGKGALAFVEEQFKD
>NZ_CP044493.1|WP_002265219.1|1376179_1377586_-|6-phospho-beta-galactosidase
MSKTLPKDFIFGGATAAYQAEGATHADGKGPVAWDKYLEDNYWYTAEPASDFYHQYPVDLKLAEEFGVNGIRISIAWSRIFPKGYGAVNPKGLAFYHNLFAECHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVAHSKAVKLFKDGGYSGEIGVVHALPTKYPYDPNNPADIRAAELEDIIHNKFILDATYLGKYSEKTMEGVNHILAVNGGQLDLREEDFAALEAAKDLNDFLGINYYMSDWMRAFDGETEITHNAKGEKGSSKYQIKGVGRREAPVNVPKTDWDWIIYPQGLYDQIMRVKQDYPNYKKIYITENGLGYKDEFVNHTVYDDARIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERYPKKSAYWYKKLAETQIID
>NZ_CP044493.1|WP_002268127.1|1395994_1396897_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MPLTVITVKNAPPSLRGDLTKWMQEIATGVYVGNFNTKVREQLWNRVKDSVSNGEATLSFAYRNEIGYCFDTMNAQRKVVDFEGIPLVQLPNSNNNIKEEMNLGFSHAAKFRKIRRYSSHSKNNSPSLVPYVVIDIETDGLDENENSIIEIGAVKIGPSQLEEFNYLVKYDKILPKQISKLTGISQELLDRDGKDLQVVLQEFLNFIGNHDLVGYGINFDIKFINKKLKELNQPLLKNRVYDLMQYAKKEKLFLDNYKLQTVLKAYEIEDEVPHRALHDSKLIYDLSTKMNKFLKGINQK
>NZ_CP044493.1|WP_002268884.1|1396898_1397840_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MKEKFGAKKTSLKELPKISDRVSFIYVEHAKINRVDSAITVSDSNGTVRIPAAMLGVLLLGPGTDISHRAVELIGDTGTSIVWIGERGVRQYAHGRALAHSTKFLEKQARLVSNSRSRLKVARKMYQMRFPNEDVSSLTMQQLRGREGARIRKVYRLQSKKYKVPWTKREYSPDNFEDGTAVNQSLSAANVALYGLVHSIVVALGASPGLGFVHTGHDLSFVYDVADLYKAEFTIPIAFEVAANHEIGDDIGRITRLKIRDSFVDGKLMARIVKDIQYLLDIEAEDELLIDILALWDDREKLVKHGVSYKENS
>NZ_CP044493.1|WP_002268883.1|1397841_1398489_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MIMYISRVEIDMNNRRKVKNLTHVGAFHDWVERSFPNEIEKQIRTRKLWRIDTLQGKNYLIIISSEKPDLLLLEKYGVEGSAQTKLYDNFLNTLKKGNRMKFRVALNPVISLPSSDNKKRGIVKPHVTSEYQMKYLKDRSEKNGFLLDEAEFLIVERGYEVFKKSNPKPIRLIKTVYEGTLTISDVDRFRKVLTEGIGKKKAYGFGMMTVIPVGD
>NZ_CP044493.1|WP_002268124.1|1398488_1399205_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MKTILLKFAGPLQSWGTSSHFETRHTDFYPSKSAVIGMIAASLGYRRNEDEKIRKLNELDFAVRVDQQGNLLRDWHNAKSDKRKDPYTTNRYYLEDAVFVVAISHQNYAFIQMIEDGLRSPYFQPFMGRRACPLPVDFIVQVTNDSALDSLKQLDWQAATWYMKRQSTDDRISLEIYTDSYLTGKESYQLRQDKVLSFSQKERKFGFRYESRVRVEVLNPLWQEQSSTEHDIFNSIGD
>NZ_CP044493.1|WP_002268123.1|1399210_1400431_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTNQEKLFLDIHVIQTLPPSNINRDDTGGPKTAQYGGVRRARVSSQSWKRAMREYLVNSLKLENTSARTVKIVEYIAKQIQLIDQSIEIDTAKKLVKEMLERVVKKKSGKDEKIFVIDNEYKLSALFFISKFQSIKLAELALNPEFVEICNKFDALSGKVKEDKEYKKSKEYKEIDAAYKIQMKKIKEILNELLSIDIAFFGRMLASDPSLNEDASSQVAHAISTHAIQTEFDFFTAIDDLAPEDNAGAGMLGTVEFNSSTLYRYANIAIHELESQLDDGESAVNALKLFVEAFAKSLPTGKVNTFANQTLPQALVVTVRNDRPVNLVSAFEEPVKSSNGYVTKSIEKLSKEFVKVEKMVKKPVLSFYVSLEEVEALTKVGIEKNSITELVEDFSQELSELIQNR
>NZ_CP044493.1|WP_002268122.1|1400420_1401017_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSEESYVRMYFVTKQILIKLNKQQNTSAGKAMLARLRHSVGKPISEAKEVWPILFENVPENFLSQYDNASYEEIAILTAIQLYALYQQGMSHNVFDDSAKKFQNIGYSLKSIRTRVDTVAVDRRFNTMITATTFEELVHHLRQLITLLKSKTPETKIDFARLATDLYCFLRDYQETVRLKWARQYYKHSSEEEAENDN
>NZ_CP044493.1|WP_002268121.1|1401016_1402699_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSRFNLLDEPWISVVFDEKGSTKEVSLLDFFQNAHHYKDLAGDTKTQDFAVLRVLLAVLHTVFSRFDANGNVYGYLEIDEKYRQIEEIEEDDLEEYEDDLYETWLTLWQNRQFPDIIEEYLKKWRDRFYLFDEEYPFFQVRREDISEDKINQKSATSIFGRNVNKTISESNNKITLFSPRDNRNKDILSASEVARWLLTFQGYTGVFDKTTFKGGKGSPSKGWIYDLGGVFVKGSNLFTTLLLNFILPYQERDNLINIQSPSWEFDSNELISMYLAGKEINNIAGLYTVWSRGIYIDSNPDLSLPFSFEIVKLPDINHQDNFLEPMTLWIYNQLGNNKGHYTPKKHVSNQSLWRSFGLLVNGQNNQRRPGIIDWLEVECIRDVIGIIPITICSVSMKDDGNTSSRMPTDEIIDTFSINEFVLTDFQENGWTTRINNIVEETKTVISVIYKDYVDDIRKIRNIKSGTFITQKLEELYFKIDQPFRQWLSGIHYGDEKDEKVFKWRGVLKKLVHQEAKILLQDGGPRDYIGIVDKDNETVKNIVTAYESFNYRLNKNLKEKK
>NZ_CP044493.1|WP_002271176.1|1402691_1405478_-|CRISPR-associated-helicase/endonuclease-Cas3
MDKKVLRYNFWAKKREEKGQFLWLPLMQHLEDTKNVAGLLWEHWLGEGQKALIIASLKTGKKDEKTAKQLAQFLAAVHDIGKATPVFQSKKGYANSKDLDLELLEKLERAGFEGISSITLANPEKSPHALAGQYILHYNKVKEDIATIVGGHHGKPVDDRATYKNQRSQESNYYQSGKSGNTIYQKWERAQEEILNWALEVSGFKSVDELPTIKQPAQVILSGLLIMADWIASNEDYFPLISIDEREVENKADRLSGFEKWKRSSLWVSRNTWDFEGLYQARFDFEPRDVQAVLSKTIADTEQPGIFILEAPMGIGKTEAALVATEQLAEKTDRNGIFFGLPTQATSNGIFPRIEKWLESIKEDLDDNISIQLVHGKAALNADFSELPKGISINIDDFENGSVIVNEWFSGRKTAVLDDFVVGTVDQFLMLALKQKHLALRHLGFSKKVVVIDEVHAYDAYMNQYLLEALRWMGAYGVPVIILSATLPAERREKLLKSYMFGMGKRFEEKEKEQLSKQLKTEAYPLITYNNGFDICQITEFKKGENKKILLSQLEEEDLLDTVKGLLSDGGVAGIIVNTVKRAQKIAKVFADSLGEDMVEIFHSGFIATERVRKEQELLKMIGKDANRPYRKIIIGTQVIEQSLDIDFDVMISDLAPMDLLIQRMGRLHRHKIDRPQKHVFPKFYVIGMNDDLKFEEGSSFVYGDYLLARTQYYLPDSINLPEDISILVQKVYDEKLELDYPTELLDKKYHNAKSEHETKIGNKESKARDYRIADPVLRETRSRKENLIGWLENSHPDDSDERAYAQVRDIEDIVEVIALKKVGDGYALFGEGEDLSELITDFNIAKKVAQNTLRLPIALTKSYNVDDTIKELEMYSRMNLNNWQDSSWLKGALGIIFDENNEFLIGGYKLVYDEKYGVRMEEIENHE
>NZ_CP044493.1|WP_002267326.1|1405667_1406651_-|WYL-domain-containing-protein
MDEFNQVERFLYLYTELYKGNTISKQVYLDKFGVSDASFNKDIRKLKDAARHLNLDFDIKINKKESYYYLDYTSETGGNLSDIEAYTLSKILLESRALSKKKTKNIIKKLINRTVNEDYRTILDKQTENELSFYKQLNYFNDENHDQNYLSNLGKLSQAVEDTLKTEIPIKIEYSSKGETKSALILPFAILFHEYYFYITSYKFENEEWVSRTYRLDRIESISNADGKEIVKAQAFFHKYPSPSLIRDQVIMMFSGEPYLIRLKIVDKTITEYLKDALPTLQVIDEEEAIYEIRTLGVEGIQLFLRRYGSQVEFVSMTELNTGDNEG
>NZ_CP044493.1|WP_002262921.1|1407315_1407561_-|membrane-protein
MLILGWVATFMSIMMYVSYIPQIMNNLAGNKGDFIQPSVAALNCTLWVIYGLCKEKRDLPLAAANMPGIVFGLIAAITALV

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Crispr_ID: NZ_CP044493_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP044493_3

1632836-1633926

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CRT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	PILER-CR
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CRISPRCasFinder

16 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,WYL

The CRISPR arrays of NZ_CP044493_3

>merge|NZ_CP044493|3|1632836-1633926|CRT,PILER-CR,CRISPRCasFinder
AAAAAACAAACCCAACCTTTAAAGGGTGCGACAAAAACCAGAAGTGTTTATTTCAGGATTTTTTGAAATTTCAATCCACGCACCCGTGAAGGGTGCGACGTATTCTTGGACGTATTTTTCTGCTTCTCCTCTAATTTCAATCCACGCACCCGTGAAGGGTGCGACCTTTCTACCTCTCCTTCATATTCCAGCCATCTTATTTCAATCCACGCACCCGTGAAGGGTGCGACACAAGAACTATCAAGTGACAGCGCAAACAATCAATTTCAATCCACGCACCCGTGAAGGGTGCGACTCAATACCATGTTTCATTGATTTAACATAATATATTTCAATCCACGCACCCGTGAAGGGTGCGACACCATTGGTCTAACACTGAAGTTCAAGATTGTCAAATTTCAATCCACGCACCCGTGAAGGGTGCGACAGCGTGTTGATTGCAACATTCTTAGCTGCGTTATTATTTCAATCCACGCACCCGTGAAGGGTGCGACTCAATAGCTTTTAATGTTTCGTCTTGTTCCCTCTTATTTCAATCCACGCACCCGTGAAGGGTGCGACTTACCGACGGCTTGCAAAGCTTCCTTGTGCTTAATTTCAATCCACGCACCCGTGAAGGGTGCGACTTGATAAGCTTAGAGATGACGCCGAAACTCGTGAAATTTCAATCCACGCACCCGTGAAGGGTGCGACATTTTGGACATTAGGGTCCCCGTTTGACTCGCGTTATTTCAATCCACGCACCCGTGAAGGGTGCGACTTGTGCTATCGCTGACTTTCCAAAAGTTTCTTTCATTTCAATCCACGCACCCGTGAAGGGTGCGACTTTCTGGCTGCTGCCATTGATAACAGTCAGACAAATTTCAATCCACGCACCCGTGAAGGGTGCGACAAATAGTTAGCTTCCGCTTCCGCTTGCGCTATAATTTCAATCCACGCACCCGTGAAGGGTGCGACCTTCTGACAGGACTTCTAGCGACAAGTTATTACATATTTCAATCCACGCACCCGTGAAGGGTGCGACGTGACCAGCGACGGCATTGCTATCCCAATTATTTTATTTCAATCCACGCACCCGTGAAGGGTGCGAC

>NZ_CP044493|3|3|1632836-1633926|CRT
AAAAAACAAACCCAACCTTTAAAGGGTGCGAC	AAAAACCAGAAGTGTTTATTTCAGGATTTTTTGAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	GTATTCTTGGACGTATTTTTCTGCTTCTCCTCTA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CTTTCTACCTCTCCTTCATATTCCAGCCATCTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ACAAGAACTATCAAGTGACAGCGCAAACAATCA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TCAATACCATGTTTCATTGATTTAACATAATAT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ACCATTGGTCTAACACTGAAGTTCAAGATTGTCAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	AGCGTGTTGATTGCAACATTCTTAGCTGCGTTATT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TCAATAGCTTTTAATGTTTCGTCTTGTTCCCTCTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTACCGACGGCTTGCAAAGCTTCCTTGTGCTTA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTGATAAGCTTAGAGATGACGCCGAAACTCGTGAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ATTTTGGACATTAGGGTCCCCGTTTGACTCGCGTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTGTGCTATCGCTGACTTTCCAAAAGTTTCTTTC
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTTCTGGCTGCTGCCATTGATAACAGTCAGACAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	AAATAGTTAGCTTCCGCTTCCGCTTGCGCTATA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CTTCTGACAGGACTTCTAGCGACAAGTTATTACAT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	GTGACCAGCGACGGCATTGCTATCCCAATTATTTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC

>NZ_CP044493|3|4|1632903-1633926|PILER-CR
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	GTATTCTTGGACGTATTTTTCTGCTTCTCCTCTA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CTTTCTACCTCTCCTTCATATTCCAGCCATCTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ACAAGAACTATCAAGTGACAGCGCAAACAATCA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TCAATACCATGTTTCATTGATTTAACATAATAT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ACCATTGGTCTAACACTGAAGTTCAAGATTGTCAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	AGCGTGTTGATTGCAACATTCTTAGCTGCGTTATT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TCAATAGCTTTTAATGTTTCGTCTTGTTCCCTCTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTACCGACGGCTTGCAAAGCTTCCTTGTGCTTA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTGATAAGCTTAGAGATGACGCCGAAACTCGTGAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ATTTTGGACATTAGGGTCCCCGTTTGACTCGCGTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTGTGCTATCGCTGACTTTCCAAAAGTTTCTTTC
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTTCTGGCTGCTGCCATTGATAACAGTCAGACAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	AAATAGTTAGCTTCCGCTTCCGCTTGCGCTATA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CTTCTGACAGGACTTCTAGCGACAAGTTATTACAT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	GTGACCAGCGACGGCATTGCTATCCCAATTATTTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC

>NZ_CP044493|3|3|1632903-1633926|CRISPRCasFinder
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	GTATTCTTGGACGTATTTTTCTGCTTCTCCTCTA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CTTTCTACCTCTCCTTCATATTCCAGCCATCTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ACAAGAACTATCAAGTGACAGCGCAAACAATCA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TCAATACCATGTTTCATTGATTTAACATAATAT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ACCATTGGTCTAACACTGAAGTTCAAGATTGTCAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	AGCGTGTTGATTGCAACATTCTTAGCTGCGTTATT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TCAATAGCTTTTAATGTTTCGTCTTGTTCCCTCTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTACCGACGGCTTGCAAAGCTTCCTTGTGCTTA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTGATAAGCTTAGAGATGACGCCGAAACTCGTGAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	ATTTTGGACATTAGGGTCCCCGTTTGACTCGCGTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTGTGCTATCGCTGACTTTCCAAAAGTTTCTTTC
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	TTTCTGGCTGCTGCCATTGATAACAGTCAGACAA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	AAATAGTTAGCTTCCGCTTCCGCTTGCGCTATA
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	CTTCTGACAGGACTTCTAGCGACAAGTTATTACAT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC	GTGACCAGCGACGGCATTGCTATCCCAATTATTTT
ATTTCAATCCACGCACCCGTGAAGGGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP044493.1\|WP_002263670.1\|1643637_1643883_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350305
NZ_CP044493.1\|WP_002263665.1\|1635399_1636071_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|224385
NZ_CP044493.1\|WP_002280402.1\|1639726_1642135_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP044493.1\|WP_002263664.1\|1634073_1634367_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_CP044493.1\|WP_002262537.1\|1615947_1617180_-\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|235987
NZ_CP044493.1\|WP_002262531.1\|1621229_1621664_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP044493.1\|WP_002268387.1\|1636951_1638883_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|273839
NZ_CP044493.1\|WP_002273005.1\|1621992_1622784_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|180910
NZ_CP044493.1\|WP_002263667.1\|1638882_1639626_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP044493.1\|WP_002263672.1\|1644021_1644327_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225215
NZ_CP044493.1\|WP_002266864.1\|1617228_1617963_-\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP044493.1\|WP_002268386.1\|1636072_1636948_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|274216
NZ_CP044493.1\|WP_002262534.1\|1618900_1619866_-\|enoyl-[acyl-carrier-protein]-reductase-FabK	unknown	unknown	gnl\|CDD\|132195
NZ_CP044493.1\|WP_002262533.1\|1619968_1620193_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP044493.1\|WP_151416407.1\|1617977_1618898_-\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP044493.1\|WP_151416408.1\|1634377_1635403_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP044493.1\|WP_002300589.1\|1620252_1621230_-\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NZ_CP044493.1\|WP_002262529.1\|1622947_1623592_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223710
NZ_CP044493.1\|WP_151416409.1\|1642379_1643354_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP044493.1\|WP_002262538.1\|1615456_1615945_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl\|CDD\|235777

Protein	Function_ID	Function_description	E-value
NZ_CP044493.1\|WP_002263670.1\|1643637_1643883_-\|hypothetical-protein	gnl\|CDD\|350305	cd18738, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.90037e-05
NZ_CP044493.1\|WP_002263665.1\|1635399_1636071_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	7.3791e-30
NZ_CP044493.1\|WP_002280402.1\|1639726_1642135_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.29954e-98
NZ_CP044493.1\|WP_002263664.1\|1634073_1634367_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.51524e-31
NZ_CP044493.1\|WP_002262537.1\|1615947_1617180_-\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|235987	PRK07314, PRK07314, beta-ketoacyl-ACP synthase II.	0
NZ_CP044493.1\|WP_002262531.1\|1621229_1621664_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.10415e-16
NZ_CP044493.1\|WP_002268387.1\|1636951_1638883_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	3.77682e-102
NZ_CP044493.1\|WP_002273005.1\|1621992_1622784_-\|enoyl-CoA-hydratase	gnl\|CDD\|180910	PRK07260, PRK07260, enoyl-CoA hydratase; Provisional.	2.27956e-178
NZ_CP044493.1\|WP_002263667.1\|1638882_1639626_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.21553e-102
NZ_CP044493.1\|WP_002263672.1\|1644021_1644327_-\|hypothetical-protein	gnl\|CDD\|225215	COG2336, MazE, Growth regulator [Signal transduction mechanisms].	1.3401e-07
NZ_CP044493.1\|WP_002266864.1\|1617228_1617963_-\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	1.2052e-127
NZ_CP044493.1\|WP_002268386.1\|1636072_1636948_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|274216	TIGR02589, conserved_hypothetical_protein, CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csd2 protein of the Dvulg subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02590, the Csh2 protein of the Hmari CRISPR subtype.	1.35245e-147
NZ_CP044493.1\|WP_002262534.1\|1618900_1619866_-\|enoyl-[acyl-carrier-protein]-reductase-FabK	gnl\|CDD\|132195	TIGR03151, enACPred_II, putative enoyl-[acyl-carrier-protein] reductase II. This oxidoreductase of the 2-nitropropane dioxygenase family (pfam03060) is commonly found in apparent operons with genes involved in fatty acid biosynthesis. Furthermore, this genomic context generally includes the fabG 3-oxoacyl-[ACP] reductase and lacks the fabI enoyl-[ACP] reductase.	5.13667e-168
NZ_CP044493.1\|WP_002262533.1\|1619968_1620193_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	8.86201e-18
NZ_CP044493.1\|WP_151416407.1\|1617977_1618898_-\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	3.99963e-125
NZ_CP044493.1\|WP_151416408.1\|1634377_1635403_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	1.09592e-179
NZ_CP044493.1\|WP_002300589.1\|1620252_1621230_-\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	2.08046e-174
NZ_CP044493.1\|WP_002262529.1\|1622947_1623592_-\|HAD-family-phosphatase	gnl\|CDD\|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	3.20316e-45
NZ_CP044493.1\|WP_151416409.1\|1642379_1643354_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	4.0248e-14
NZ_CP044493.1\|WP_002262538.1\|1615456_1615945_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	5.90006e-68

>NZ_CP044493.1|WP_002262529.1|1622947_1623592_-|HAD-family-phosphatase
MATKAVIFDMDGVLFDTEGFYYRRREIFLNDKGISIKHIPPAFFIGGNMKQVWQKILEDDYANWDVEQLQKDYTSYKNKHPLPYQNLIFPDVKVILEKLKQHQFKIALASSSTKSDILLALNKTGIYDYFDLVLSGEEFPESKPHPAIYNEAAYQLGFPKSELLIIEDSEKGIAAGVSAGIEVWAIKDRTFGLNQRAASRLFSNLTEVVDFLLK
>NZ_CP044493.1|WP_002273005.1|1621992_1622784_-|enoyl-CoA-hydratase
MDFKEILYNVDNGVATLTLNRPEVSNGFNIPICEEILKAIDTAKKDDTVQILLINANGKVFSVGGDLVEMQRAVDADDVQSLVRIAELVNKISFALKRLPKPVVMSTDGAVAGAAANIAVAADFCIASDKTRFIQAFVNVGLAPDAGGLFLLTRAIGITRATQLAMTGEALNAEKALEYGIVYKVCEPEKLEKMTDRVITRLKRGSVNSYKAIKEMVWQSSFAGWQEYEDLELELQKSLAFTNDFKEGVRAYTEKRRPKFTGK
>NZ_CP044493.1|WP_002262531.1|1621229_1621664_-|MarR-family-transcriptional-regulator
MDYKQINTYLVDIFNKIMIIEEMSLKTSQFNDVSLKEMHTVDIIGKNANVTPSDIAHELLVTLGTVTTSLNKLEKKGYIERTRSQLDRRVVYLTLTQKGRLLYRLHNRFHKNVVNRITEAMDATELGALEKGLRNLHQFLEGLV
>NZ_CP044493.1|WP_002300589.1|1620252_1621230_-|ketoacyl-ACP-synthase-III
MTFAKISQAAYYVPSQVVTNDDLSKIMDTSDEWITSRTGIRERRISQSEDTSDLASQVAKELLKKASLKAKEIDFIIVATITPDAMMPSTAACVQAKIGAVNAFAFDLTAACSGFIFALSAAEKMIKSGQYQKGLVIGAEVLSKIIDWSDRTTAVLFGDGAGGVLLEADSSEHFLFESIHSDGSRGESLTSGGHAVSSPFSQVDKKDDCFLKMDGRAIFDFAIRDVSKSISTLIRKSDMPVEAIDYFLLHQANIRILDKMAKKIGADREKFPANMMKYGNTSAASIPILLAECVENGTIELNGSHTVLLSGFGGGLTWGSLIVKI
>NZ_CP044493.1|WP_002262533.1|1619968_1620193_-|acyl-carrier-protein
MAVFEKVQEIIVEELGKDTDEVKLETTFDELDADSLDVFQVISEIEDEFDIQIESEDGLNTVGDLVAFVEEKTK
>NZ_CP044493.1|WP_002262534.1|1618900_1619866_-|enoyl-[acyl-carrier-protein]-reductase-FabK
MKTRITELLDIEYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGGNAPKEVVKANIDKIKAVTNKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKYIERFHEAGITVIPVVPSVALARRMEKLGADAVIAEGMEAGGHIGKLTTMTLVRQVVDAVNIPVIGAGGVADGRGAAAVFMLGAEAIQVGTRFAVAKESNAHANFKKKILKAKDIDTVISASIVGHPVRAIKNKLSSAYATAEKEFLRGEKSQEDIEVLGAGALRNAVVDGDVDNGSVMAGQIAGFVTKEETCEEILKDLYYGAAKVIKAEAARWADVEK
>NZ_CP044493.1|WP_151416407.1|1617977_1618898_-|ACP-S-malonyltransferase
MTKTAFLFAGQGAQKLGMASDLYEIYPVVKETFKTAHSILGYDVRALIDNDEEKLNQTRYAQPAILTTSVAIYRLLKEKGYQPDIVAGLSLGEYSALVAAGAISFEDALALVAKRGEFMETAAPAGVGKMVAVMNTDPRLIEEICQKASSKGIVSPANYNTPTQIVIGGEVAAVDYAVELLKEAGSKRLISLKVSGPFHTALLESASQKLGQALENIKFSDFTLPLVGNTKAEIMEEHEIKSLLARQVKEPVRFYESIAVMQKFGVNNYVEIGPGKVLSGFVKKIDKSAKISAVEDLASLQAFLDN
>NZ_CP044493.1|WP_002266864.1|1617228_1617963_-|3-oxoacyl-[acyl-carrier-protein]-reductase
MEIKNKNVFITGSTRGIGLAIAHKFAQAGANIVLNGRSEISQDLVAEFKDYGVKVATISGDVSHFEDAKRMVDEATEALGSVDILVNNAGITNDKLMLKMTEEDFERVLKINLTGSFNMTKAVLKPMTKARQGAIINMSSVVGLAGNVGQANYAASKAGLIGFTKAVAREVAARNVRVNAIAPGFIESEMTERIPDKMKDAMLNQIPMKTFGKTENVAEVAIFLAQQDYLTGQVIAIDGGMTMQ
>NZ_CP044493.1|WP_002262537.1|1615947_1617180_-|beta-ketoacyl-ACP-synthase-II
MTLKRVVVTGYGVTSPIGHTPEDFWNSLHDGKIGIKPITKFDASEIPVFNAGEIQDFPFDKYFVKKDKNRMDTYSLYAIYAAMEAIENAALDMAQEIRDRVGVIVSSGIGGLQELEDQIIRMHERGMKRIKPMFIPKALSNMGAGNIALKIGAQGVCKSITTACASANDAIGEAFREIKYGFHDVILAGGSEASITKIGIGGFNALTALSTTEDPARSAIPFDKDRNGFVMGEGAAVLILESLEHAQKRGARILAEVVGYGSNCDAYHMTTPTPDGSGAAKAIKLAINEAGISPEEVNYVNAHGTSTQANEKGESKAIVAVLGKDVPVSSTKSFTGHLLGAAGGVEAIATIEAIRNHFVPMTAGTKELSEDIEANVVYGQGQEADIKYAISNTFGFGGHNAVLAFKRWED
>NZ_CP044493.1|WP_002262538.1|1615456_1615945_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MNISEIKDLMAQFDTSSLREFSYKNGTDELSFSKNRQGSISSVQTVPVPAANSVSTVASVDAEAVPAISKNEESTAAAPVAETAEGEIVESPLVGVAYLASAPDKPAFISVGDSVKKGQTLLIIEAMKVMNEVPAPKDGVVTEILVANEEVVEFGKGLVRIK
>NZ_CP044493.1|WP_002263664.1|1634073_1634367_-|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETVAGRKRLRHVAKLCVDYGQRVQHSVFECSVTPAEFVEIKNELSTIIDQESDSIRFYLLGKNWQNRVETMGRDDSYDPDVGILLL
>NZ_CP044493.1|WP_151416408.1|1634377_1635403_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQDNFYLTRERDNIVIKQEGAVVHRFPYRIIYGIVCFSYLGASPSLIELCAKNQINLSFHTPQGRFCGRFVGPANGNVLLRRQQYRLADNDLSLAYAKRFILAKISNARKYLLRFRRDHRAKINQQLFEEVNTELTFALEMVATARDKDTLLGIEGQAANHYFRAFNDLVLTDKQTFQFKGRTRRPPQDYVNALLSFGYSMLTYECQSALEAVGLDSYVGFYHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLSKKHFDIKENGSVILTEKGRAIFIEAWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLSKAIRGELESYPPFLI
>NZ_CP044493.1|WP_002263665.1|1635399_1636071_-|CRISPR-associated-protein-Cas4
MAYAEDDYLMLSGIQHFQFCKRQWGLIHIEQQWAENEATAHGQILHQKADNPYIREKRKDIITSRAMHVSSKTLGLYGILDVVEFHKDKNGVTLKGKRGKWLPRIVEYKRGKPKRDTRDIVQLVAQTICLEETFGCPIETGCLYYHSVNQKKVIEITEALRQEVFDLAGQMHYYYDNKIIDKAEYFKNCPLCSLVDICKPRLSKKSRNVANYIKRHVMSEESL
>NZ_CP044493.1|WP_002268386.1|1636072_1636948_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEQKIDFMVTVEVREANANGDPLSGNMPRTDAKDYGLMSDVSIKRKIRNRMQDMGQPIFVQARDRVDDCIYSLKQRLENKEFFDTVKEGSKKKKSVENFVKQINAEWLDVRSFGQVFAFDGYSAANVRGPVSISWAKSLEKVVTQSMQITKSTNSELNSKTELESSTMGTKHFVDYGVYVIKGSINPNFAEKTGFSDADAEIIKEVLVSLFENDASSARPEGSMRVREVFWFTHSNKLGNVSSARVFDLLEFDKEKQDKDSYEDYAIHLNQEELAEYEAKGLQVEIIEGL
>NZ_CP044493.1|WP_002268387.1|1636951_1638883_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDLFTSLLKAYEKAEEIGLVDQQTGDNPVLLPIYHDNKVIKNNDIYIEILLDNEGAFYKARKFEIGENVIFPVTYESSNRTSTKIAPHPIVDSWYYVMYSELRKEKHQRYLQNLDNWIIQTENNKVENFLKIIKKFVENPESVELVLNSAFGSDCQIQEEFVDNNGKIQEGSLIFGEKKQKIALKDIKLSFKILEFDGLRDVSVSNFNEMHHDFINYINNNSTEIGIGICNISGKEDRIIKNHRKPKGVFSNGKLISQNNKIAYLGDRFPNENASSDIIKIGYETSEKIHLMIKYLLENNNSHTWLGTSQYLINWFSDDLSNDSQLDIVKPEFDDLFEDDEEEKQVFIKPNEENKKIGSSFVRGQKLFSNNATYNIAILNENKGRIALKYFRQLQVSQLLKNLESWQENYSWEAKTKAGNYELKKTPTFNEIINAAYGVDRERYLELDNDSFRSDQYQQLVTALIDGKPLPNTIVKKLEDNIRQRQKYSKHWYQVQQVSLAVLQKQYGREFTPMLDHQETDRSYLFGRLLAIYELFEAQRYALDGSSQERVTNAERYWNAYTGQPAKMMTHLENKIKPYEEVLKLNKPGIWHKLEKERKEIIQLMTPMYAHKNFTQSLDYKFIFGYYAEKQFYYTKQAKENEE
>NZ_CP044493.1|WP_002263667.1|1638882_1639626_-|type-I-C-CRISPR-associated-protein-Cas5
MYRSRNFYARIRGDRALFTNPATKGGSERSSYSVPTRQALQGIIDGIYHKPTFTNVITEVKVVNQIQTELHGVRALLHDYSADLSYVSYLSDVEYLVKFHFIWNENREDLIQDRLPKKHEAIMERSIRKGGRRDIFLGTRECFGLVDEISQEEYETIPSYYNGVTIDLGIMFHSFAYPTSKDTPLKSYFTKTVMENGAIKFKPQSECEIVNTLSSYAFKSLGQLKSVDDEYVDDEYEEYEAMEKGEG
>NZ_CP044493.1|WP_002280402.1|1639726_1642135_-|CRISPR-associated-helicase/endonuclease-Cas3
MKMKLAHKNNTGEEQSLEDHSFNVANKAREDAEFIGQGDLLFLLGMFHDLGKADEKFQNKLTKNPTMHVDHAYAGAKYLYEKIKIRLSAKGVDKATRLQFNEIVAYVIAAHHGMFDIVDLESEQHAYNKLRNRIARPKSDYHFDSDVTNFANFLETKLEHYGYQDLGMLIDKSFENYQQALSKLDCQDSSEEVYYQSCFVRLYLSLLKNADILDTINAYGLLINPLKQEEKIRLNRSYLEAIEKKYGEFGSPTTRLNEIRSQIAERVKSRGESDSTGIYRLDLPTGAGKTNLSMRYAFHQLVDQDRSRFFYITPFLSVLEQNAAAIKKVIGEDGVLEHHSNVVQNKQENEDKGDEKESLLPEYLIESWDSPVVLTSMVQFFQTLFKTKSANIRRFSSLANSVLILDEVQSLPIEVTALFNLTMNFLNKVMNTTIILCTATQPAYDSTAIKHKLSYGGKYGEATDMVELTHDEKEVFSRTELRKFDETNQNSKLSDLVDFVLENDESILVIFNTKKTVDRFYSLLEKLTDRPIYQLSTNMCAQHRLDIISEIKQGLEDGLPLICISTQLIEAGVDVDFNHVIRSYAGIDSIVQASGRCNREGKRDKGQVTLINLTSEEENISPLKEIKAKKDATEYILHKISSPIDTSLLNRDFFEYYYANNQGSMDYPLEHDGESVYDYLSVNFYQKKVGFKGKLKQAFKTAGLKMNLINNETIGILVPYRDAAEKLLILEELCKSDYPSEEDYRAIKALLKELQSYTVNVREHNQILEATKPYLNGQIQILSDSYYDDKKGITLESASFLM
>NZ_CP044493.1|WP_151416409.1|1642379_1643354_-|WYL-domain-containing-protein
MAESKTKRLLYFMSELEKGNQINKEEYIAKFNISDRTMKEDVSELKTNLKELRPNMQIKFSRKHVCYFASYEQGYGNLKYNQAVILSKILLESRALRKEEVAEIINIFVERAVDDKERTRIKKLTQFELNSYQELKFYQKSNKSILPTISAIFDAIVDQRPLAFSYTKPSSKVEEYIVLPISVIFDNHYFYCISYKLDNCFQSRYELQELRYFRVDRFKTIHKSISNSAFALTEEEQERLITDEQVRYQTFSMLSDQKWVRIQFRYTGQFRDVLEADIPKLKMINELEEGIIYEIETLSLLGFQKYIQRFDGDFVFLNIKSIKK
>NZ_CP044493.1|WP_002263670.1|1643637_1643883_-|hypothetical-protein
MGKIARLELEKLVKIFQVLDVTKENCLQALSMKMPDFEGAVVAAVALSNDINIVVTRNVTDFQDSELIIYLPEEFLERLKR
>NZ_CP044493.1|WP_002263672.1|1644021_1644327_-|hypothetical-protein
MAVLLEQDRIQLKKWGNSNAFRIPQKLLKSLKFEPDQEFTIKAVDLGGHKQLVIEPLVSQNDQLSLIESLSGILSDSETVDVKDYRSERKEERLKKYESLT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP044493_2	2.4\|1393469\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393469-1393501	33	DQ386162	Streptococcus phage M102AD, complete genome	11933-11965	0	1.0
NZ_CP044493_1	1.6\|1291667\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291667-1291696	30	AM749121	Streptococcus phage M102 complete genome	25537-25566	1	0.967
NZ_CP044493_1	1.6\|1291667\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291667-1291696	30	NC_012884	Streptococcus phage M102, complete genome	25537-25566	1	0.967
NZ_CP044493_2	2.21\|1394508\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394508-1394540	33	AM749121	Streptococcus phage M102 complete genome	15941-15973	1	0.97
NZ_CP044493_2	2.21\|1394508\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394508-1394540	33	NC_012884	Streptococcus phage M102, complete genome	15941-15973	1	0.97
NZ_CP044493_2	2.21\|1394508\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394508-1394540	33	DQ386162	Streptococcus phage M102AD, complete genome	16063-16095	1	0.97
NZ_CP044493_2	2.26\|1394813\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394813-1394845	33	MT430910	Streptococcus phage smHBZ8, complete genome	10795-10827	1	0.97
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK044828	Streptococcus phage 33888, complete genome	23847-23876	2	0.933
NZ_CP044493_1	1.5\|1291601\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291601-1291630	30	NC_029030	Streptococcus phage APCM01, complete genome	30431-30460	2	0.933
NZ_CP044493_2	2.6\|1393591\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393591-1393623	33	NC_029030	Streptococcus phage APCM01, complete genome	14924-14956	2	0.939
NZ_CP044493_2	2.6\|1393591\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393591-1393623	33	MT430910	Streptococcus phage smHBZ8, complete genome	17227-17259	2	0.939
NZ_CP044493_2	2.13\|1394019\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1394019-1394051	33	AM749121	Streptococcus phage M102 complete genome	30950-30982	2	0.939
NZ_CP044493_2	2.13\|1394019\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1394019-1394051	33	NC_012884	Streptococcus phage M102, complete genome	30950-30982	2	0.939
NZ_CP044493_2	2.13\|1394019\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1394019-1394051	33	DQ386162	Streptococcus phage M102AD, complete genome	30456-30488	2	0.939
NZ_CP044493_2	2.21\|1394508\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394508-1394540	33	MT430910	Streptococcus phage smHBZ8, complete genome	16119-16151	2	0.939
NZ_CP044493_2	2.22\|1394569\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394569-1394601	33	DQ386162	Streptococcus phage M102AD, complete genome	30484-30516	2	0.939
NZ_CP044493_2	2.35\|1395362\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395362-1395394	33	MT430910	Streptococcus phage smHBZ8, complete genome	24983-25015	2	0.939
NZ_CP044493_2	2.35\|1395362\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395362-1395394	33	NC_029030	Streptococcus phage APCM01, complete genome	7215-7247	2	0.939
NZ_CP044493_2	2.35\|1395362\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395362-1395394	33	AM749121	Streptococcus phage M102 complete genome	7078-7110	2	0.939
NZ_CP044493_2	2.35\|1395362\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395362-1395394	33	NC_012884	Streptococcus phage M102, complete genome	7078-7110	2	0.939
NZ_CP044493_2	2.35\|1395362\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395362-1395394	33	DQ386162	Streptococcus phage M102AD, complete genome	7199-7231	2	0.939
NZ_CP044493_2	2.43\|1395850\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395850-1395882	33	AM749121	Streptococcus phage M102 complete genome	17205-17237	2	0.939
NZ_CP044493_2	2.43\|1395850\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395850-1395882	33	NC_012884	Streptococcus phage M102, complete genome	17205-17237	2	0.939
NZ_CP044493_2	2.43\|1395850\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395850-1395882	33	DQ386162	Streptococcus phage M102AD, complete genome	17327-17359	2	0.939
NZ_CP044493_3	3.7\|1633263\|35\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633263-1633297	35	AM749121	Streptococcus phage M102 complete genome	14021-14055	2	0.943
NZ_CP044493_3	3.7\|1633263\|35\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633263-1633297	35	NC_012884	Streptococcus phage M102, complete genome	14021-14055	2	0.943
NZ_CP044493_3	3.7\|1633263\|35\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633263-1633297	35	DQ386162	Streptococcus phage M102AD, complete genome	14143-14177	2	0.943
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	KT337344	Streptococcus phage phiARI0274b, partial genome	23147-23176	3	0.9
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	KT337354	Streptococcus phage phiARI0462, complete genome	28973-29002	3	0.9
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	KT337345	Streptococcus phage phiARI0285-1, partial genome	21964-21993	3	0.9
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	KT337351	Streptococcus phage phiARI0455b, partial genome	21120-21149	3	0.9
NZ_CP044493_2	2.12\|1393957\|34\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393957-1393990	34	NC_029030	Streptococcus phage APCM01, complete genome	3975-4008	3	0.912
NZ_CP044493_2	2.13\|1394019\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1394019-1394051	33	NC_029030	Streptococcus phage APCM01, complete genome	30880-30912	3	0.909
NZ_CP044493_2	2.13\|1394019\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1394019-1394051	33	MT430910	Streptococcus phage smHBZ8, complete genome	155-187	3	0.909
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK448769	Streptococcus phage Javan471, complete genome	8534-8563	4	0.867
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK449012	Streptococcus phage Javan94, complete genome	11873-11902	4	0.867
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK448684	Streptococcus phage Javan151, complete genome	8534-8563	4	0.867
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK448679	Streptococcus phage Javan137, complete genome	8173-8202	4	0.867
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK448686	Streptococcus phage Javan157, complete genome	14239-14268	4	0.867
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK448673	Streptococcus phage Javan119, complete genome	13289-13318	4	0.867
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK448698	Streptococcus phage Javan187, complete genome	8695-8724	4	0.867
NZ_CP044493_1	1.6\|1291667\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291667-1291696	30	DQ386162	Streptococcus phage M102AD, complete genome	25372-25401	4	0.867
NZ_CP044493_2	2.8\|1393713\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393713-1393745	33	MK448925	Streptococcus phage Javan386, complete genome	565-597	4	0.879
NZ_CP044493_2	2.12\|1393957\|34\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393957-1393990	34	DQ386162	Streptococcus phage M102AD, complete genome	3966-3999	4	0.882
NZ_CP044493_2	2.12\|1393957\|34\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393957-1393990	34	MT430910	Streptococcus phage smHBZ8, complete genome	28233-28266	4	0.882
NZ_CP044493_2	2.22\|1394569\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394569-1394601	33	NC_029030	Streptococcus phage APCM01, complete genome	30908-30940	4	0.879
NZ_CP044493_2	2.22\|1394569\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394569-1394601	33	AM749121	Streptococcus phage M102 complete genome	30978-31010	4	0.879
NZ_CP044493_2	2.22\|1394569\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394569-1394601	33	NC_012884	Streptococcus phage M102, complete genome	30978-31010	4	0.879
NZ_CP044493_2	2.22\|1394569\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394569-1394601	33	MT430910	Streptococcus phage smHBZ8, complete genome	127-159	4	0.879
NZ_CP044493_2	2.12\|1393957\|34\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393957-1393990	34	AM749121	Streptococcus phage M102 complete genome	3845-3878	5	0.853
NZ_CP044493_2	2.12\|1393957\|34\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393957-1393990	34	NC_012884	Streptococcus phage M102, complete genome	3845-3878	5	0.853
NZ_CP044493_3	3.8\|1633330\|35\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633330-1633364	35	NC_029030	Streptococcus phage APCM01, complete genome	1716-1750	5	0.857
NZ_CP044493_3	3.12\|1633596\|34\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633596-1633629	34	DQ386162	Streptococcus phage M102AD, complete genome	23794-23827	5	0.853
NZ_CP044493_2	2.32\|1395179\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395179-1395211	33	AM749121	Streptococcus phage M102 complete genome	14249-14281	6	0.818
NZ_CP044493_2	2.32\|1395179\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395179-1395211	33	NC_012884	Streptococcus phage M102, complete genome	14249-14281	6	0.818
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	NC_006870	Bacillus mycoides pDx14.2 plasmid	10877-10906	7	0.767
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MK215646	Bacillus phage vB_BthM-Goe5, complete genome	127534-127563	7	0.767
NZ_CP044493_1	1.3\|1291469\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291469-1291498	30	KX827369	Staphylococcus phage SpT152, complete genome	9459-9488	7	0.767
NZ_CP044493_1	1.5\|1291601\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291601-1291630	30	NC_009955	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI01, complete sequence	70155-70184	7	0.767
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	MN657052	Psychrobacter sp. strain ANT_P19 plasmid pA19P3, complete sequence	70-99	8	0.733
NZ_CP044493_1	1.1\|1291337\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291337-1291366	30	NC_028659	Klebsiella phage vB_KpnM_KB57, complete genome	37386-37415	8	0.733
NZ_CP044493_2	2.7\|1393652\|33\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1393652-1393684	33	MN693159	Marine virus AFVG_25M303, complete genome	16607-16639	8	0.758
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	MK449012	Streptococcus phage Javan94, complete genome	22057-22089	8	0.758
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP053953	Bacillus cereus strain FDAARGOS_798 plasmid unnamed2, complete sequence	276550-276582	8	0.758
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP009636	Bacillus cereus 03BB108 plasmid pBFI_2, complete sequence	152380-152412	8	0.758
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP053962	Bacillus cereus strain FDAARGOS_802 plasmid unnamed2, complete sequence	216756-216788	8	0.758
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP053950	Bacillus cereus strain FDAARGOS_799 plasmid unnamed2, complete sequence	170797-170829	8	0.758
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	42005-42037	8	0.758
NZ_CP044493_2	2.39\|1395606\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395606-1395638	33	MK449000	Streptococcus phage Javan64, complete genome	13711-13743	8	0.758
NZ_CP044493_3	3.15\|1633793\|35\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633793-1633827	35	NC_029030	Streptococcus phage APCM01, complete genome	15220-15254	8	0.771
NZ_CP044493_1	1.3\|1291469\|30\|NZ_CP044493\|PILER-CR,CRISPRCasFinder,CRT	1291469-1291498	30	NZ_CP013053	Sinorhizobium americanum CCGM7 plasmid B, complete sequence	296752-296781	9	0.7
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	1903-1935	9	0.727
NZ_CP044493_2	2.24\|1394691\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394691-1394723	33	NZ_LR135334	Enterococcus faecium isolate E7471 plasmid 4	54096-54128	9	0.727
NZ_CP044493_2	2.24\|1394691\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394691-1394723	33	NZ_LR135205	Enterococcus faecium isolate E7171 plasmid 3	48357-48389	9	0.727
NZ_CP044493_2	2.34\|1395301\|33\|NZ_CP044493\|CRISPRCasFinder,CRT,PILER-CR	1395301-1395333	33	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	543996-544028	9	0.727
NZ_CP044493_2	2.22\|1394569\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394569-1394601	33	NZ_LR134422	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 13	134685-134717	10	0.697
NZ_CP044493_2	2.23\|1394630\|33\|NZ_CP044493\|CRISPRCasFinder,CRT	1394630-1394662	33	NZ_CP020747	Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence	44984-45016	10	0.697
NZ_CP044493_3	3.3\|1633001\|33\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633001-1633033	33	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	1031216-1031248	10	0.697
NZ_CP044493_3	3.7\|1633263\|35\|NZ_CP044493\|CRT,PILER-CR,CRISPRCasFinder	1633263-1633297	35	MT197175	Klebsiella phage VLC5, complete genome	14126-14160	10	0.714

1. spacer 2.4|1393469|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 0, identity: 1.0

gatggtcttgccaaaccacggataagagccgtg	CRISPR spacer
gatggtcttgccaaaccacggataagagccgtg	Protospacer
*********************************

2. spacer 1.6|1291667|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 1, identity: 0.967

gcgtcacgcagtcgcttttaaagtttgcct	CRISPR spacer
gcgtcacgcagtcacttttaaagtttgcct	Protospacer
*************.****************

3. spacer 1.6|1291667|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 1, identity: 0.967

gcgtcacgcagtcgcttttaaagtttgcct	CRISPR spacer
gcgtcacgcagtcacttttaaagtttgcct	Protospacer
*************.****************

4. spacer 2.21|1394508|33|NZ_CP044493|CRISPRCasFinder,CRT matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 1, identity: 0.97

agagcataactaatccgacaacaatcacagttg	CRISPR spacer
agagcataactaatccaacaacaatcacagttg	Protospacer
****************.****************

5. spacer 2.21|1394508|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 1, identity: 0.97

agagcataactaatccgacaacaatcacagttg	CRISPR spacer
agagcataactaatccaacaacaatcacagttg	Protospacer
****************.****************

6. spacer 2.21|1394508|33|NZ_CP044493|CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 1, identity: 0.97

agagcataactaatccgacaacaatcacagttg	CRISPR spacer
agagcataactaatccaacaacaatcacagttg	Protospacer
****************.****************

7. spacer 2.26|1394813|33|NZ_CP044493|CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 1, identity: 0.97

tttatggccatgattttggtcatacgggctata	CRISPR spacer
tttatggccatgatttgggtcatacgggctata	Protospacer
**************** ****************

8. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK044828 (Streptococcus phage 33888, complete genome) position: , mismatch: 2, identity: 0.933

-aatctctttaacatttatctgacaatcaga	CRISPR spacer
taatttcttt-acatttatctgacaatcaga	Protospacer
 ***.***** ********************

9. spacer 1.5|1291601|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 2, identity: 0.933

gtctattaacaaaacgcgagaagagcaact	CRISPR spacer
gtctattaacaaaacacgagaagaacaact	Protospacer
***************.********.*****

10. spacer 2.6|1393591|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 2, identity: 0.939

cagagaacgagcatacatatgataattaaacta	CRISPR spacer
tagagaacgagcatacatatgataattaaactc	Protospacer
.*******************************

11. spacer 2.6|1393591|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 2, identity: 0.939

cagagaacgagcatacatatgataattaaacta	CRISPR spacer
cagagaacgagcgtacatatgataattaaactt	Protospacer
************.*******************

12. spacer 2.13|1394019|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 2, identity: 0.939

tagcgttatcggcagactagccttatatatata	CRISPR spacer
tagcgttatcggcaaactagccttagatatata	Protospacer
**************.********** *******

13. spacer 2.13|1394019|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 2, identity: 0.939

tagcgttatcggcagactagccttatatatata	CRISPR spacer
tagcgttatcggcaaactagccttagatatata	Protospacer
**************.********** *******

14. spacer 2.13|1394019|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 2, identity: 0.939

tagcgttatcggcagactagccttatatatata	CRISPR spacer
tagcgttatcggcaaactagccttagatatata	Protospacer
**************.********** *******

15. spacer 2.21|1394508|33|NZ_CP044493|CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 2, identity: 0.939

agagcataactaatccgacaacaatcacagttg	CRISPR spacer
agagcataactaatccaacaacaattacagttg	Protospacer
****************.********.*******

16. spacer 2.22|1394569|33|NZ_CP044493|CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 2, identity: 0.939

atgaaaattaaaacaggagacatttaattagcg	CRISPR spacer
agaaaaattaaaacaggagacatttaattagcg	Protospacer
* .******************************

17. spacer 2.35|1395362|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 2, identity: 0.939

aagcagacgtgctaatctctgcaaaatctgata	CRISPR spacer
aagcagacgtactaatctctgcaaaatctgaaa	Protospacer
**********.******************** *

18. spacer 2.35|1395362|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 2, identity: 0.939

aagcagacgtgctaatctctgcaaaatctgata	CRISPR spacer
aagcagacgtgctaatctctgctaagtctgata	Protospacer
********************** **.*******

19. spacer 2.35|1395362|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 2, identity: 0.939

aagcagacgtgctaatctctgcaaaatctgata	CRISPR spacer
aagcagacgtactaatttctgcaaaatctgata	Protospacer
**********.*****.****************

20. spacer 2.35|1395362|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 2, identity: 0.939

aagcagacgtgctaatctctgcaaaatctgata	CRISPR spacer
aagcagacgtactaatttctgcaaaatctgata	Protospacer
**********.*****.****************

21. spacer 2.35|1395362|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 2, identity: 0.939

aagcagacgtgctaatctctgcaaaatctgata	CRISPR spacer
aaacagatgtgctaatctctgcaaaatctgata	Protospacer
**.****.*************************

22. spacer 2.43|1395850|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 2, identity: 0.939

agcaatcgaaaaagcgcctgttgaaattaagcg	CRISPR spacer
agcaatcgaaaaagcgcctgtggaaatcaagcg	Protospacer
********************* *****.*****

23. spacer 2.43|1395850|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 2, identity: 0.939

agcaatcgaaaaagcgcctgttgaaattaagcg	CRISPR spacer
agcaatcgaaaaagcgcctgtggaaatcaagcg	Protospacer
********************* *****.*****

24. spacer 2.43|1395850|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 2, identity: 0.939

agcaatcgaaaaagcgcctgttgaaattaagcg	CRISPR spacer
agcaatcgaaaaagcgcctgtggaaatcaagcg	Protospacer
********************* *****.*****

25. spacer 3.7|1633263|35|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 2, identity: 0.943

agcgtgttgattgcaacattcttagctgcgttatt	CRISPR spacer
agcgtgttgattgcaacatttttagctgcgctatt	Protospacer
********************.*********.****

26. spacer 3.7|1633263|35|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 2, identity: 0.943

agcgtgttgattgcaacattcttagctgcgttatt	CRISPR spacer
agcgtgttgattgcaacatttttagctgcgctatt	Protospacer
********************.*********.****

27. spacer 3.7|1633263|35|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 2, identity: 0.943

agcgtgttgattgcaacattcttagctgcgttatt	CRISPR spacer
agcgtgttgattgcaacatttttagctgcgctatt	Protospacer
********************.*********.****

28. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to KT337344 (Streptococcus phage phiARI0274b, partial genome) position: , mismatch: 3, identity: 0.9

-aatctctttaacatttatctgacaatcaga	CRISPR spacer
taatttcttt-acatttatctgacagtcaga	Protospacer
 ***.***** **************.*****

29. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to KT337354 (Streptococcus phage phiARI0462, complete genome) position: , mismatch: 3, identity: 0.9

-aatctctttaacatttatctgacaatcaga	CRISPR spacer
taatttcttt-acatttatctgacagtcaga	Protospacer
 ***.***** **************.*****

30. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to KT337345 (Streptococcus phage phiARI0285-1, partial genome) position: , mismatch: 3, identity: 0.9

-aatctctttaacatttatctgacaatcaga	CRISPR spacer
taatttcttt-acatttatctgacagtcaga	Protospacer
 ***.***** **************.*****

31. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to KT337351 (Streptococcus phage phiARI0455b, partial genome) position: , mismatch: 3, identity: 0.9

-aatctctttaacatttatctgacaatcaga	CRISPR spacer
taatttcttt-acatttatctgacagtcaga	Protospacer
 ***.***** **************.*****

32. spacer 2.12|1393957|34|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 3, identity: 0.912

gcgggattactgattacactatcgcagaagatgg	CRISPR spacer
gcgggattactgattacactatcgcggaagatat	Protospacer
*************************.******.

33. spacer 2.13|1394019|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 3, identity: 0.909

tagcgttatcggcagactagccttatatatata	CRISPR spacer
tagcgttatcggcaaactagccttagatataaa	Protospacer
**************.********** ***** *

34. spacer 2.13|1394019|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 3, identity: 0.909

tagcgttatcggcagactagccttatatatata	CRISPR spacer
tagcgttatcggcaaactagccttagatataga	Protospacer
**************.********** ***** *

35. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcttttacatttatctggcaatcaga	Protospacer
**..***** ***********.********

36. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcctttacatttatctgacaatcaga	Protospacer
**..**.** ********************

37. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcttttacatttatctggcaatcaga	Protospacer
**..***** ***********.********

38. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcttttacatttatctggcaatcaga	Protospacer
**..***** ***********.********

39. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcctttacatttatctgacaatcaga	Protospacer
**..**.** ********************

40. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcttttacatttatctggcaatcaga	Protospacer
**..***** ***********.********

41. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 4, identity: 0.867

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aacttcttttacatttatctggcaatcaga	Protospacer
**..***** ***********.********

42. spacer 1.6|1291667|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 4, identity: 0.867

gcgtcacgcagtcgcttttaaagtttgcct	CRISPR spacer
gagtcgcgcagtcgctcttaaagtttgctt	Protospacer
* ***.**********.***********.*

43. spacer 2.8|1393713|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK448925 (Streptococcus phage Javan386, complete genome) position: , mismatch: 4, identity: 0.879

caaaaagatacactctatttaattgaagaagta	CRISPR spacer
caaaaagatacactatatttaattgaggaaatt	Protospacer
************** ***********.***.*

44. spacer 2.12|1393957|34|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 4, identity: 0.882

gcgggattactgattacactatcgcagaagatgg	CRISPR spacer
gtgggattactgattacactatcgcagaagacat	Protospacer
*.*****************************..

45. spacer 2.12|1393957|34|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 4, identity: 0.882

gcgggattactgattacactatcgcagaagatgg	CRISPR spacer
gcgggattactgactacactatcgcagaagacat	Protospacer
*************.*****************..

46. spacer 2.22|1394569|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 4, identity: 0.879

atgaaaattaaaacaggagacatttaattagcg	CRISPR spacer
gtaaaaattaaaataggagacttttaattagcg	Protospacer
.*.**********.******* ***********

47. spacer 2.22|1394569|33|NZ_CP044493|CRISPRCasFinder,CRT matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 4, identity: 0.879

atgaaaattaaaacaggagacatttaattagcg	CRISPR spacer
agaaaaattaaaacaggaggcgtttaattagcg	Protospacer
* .****************.*.***********

48. spacer 2.22|1394569|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 4, identity: 0.879

atgaaaattaaaacaggagacatttaattagcg	CRISPR spacer
agaaaaattaaaacaggaggcgtttaattagcg	Protospacer
* .****************.*.***********

49. spacer 2.22|1394569|33|NZ_CP044493|CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 4, identity: 0.879

atgaaaattaaaacaggagacatttaattagcg	CRISPR spacer
agaaaaattaaaacaggagacttttaaatagcg	Protospacer
* .****************** ***** *****

50. spacer 2.12|1393957|34|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 5, identity: 0.853

gcgggattactgattacactatcgcagaagatgg	CRISPR spacer
gcgggattactgattatactattgcagaagacat	Protospacer
****************.*****.********..

51. spacer 2.12|1393957|34|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 5, identity: 0.853

gcgggattactgattacactatcgcagaagatgg	CRISPR spacer
gcgggattactgattatactattgcagaagacat	Protospacer
****************.*****.********..

52. spacer 3.8|1633330|35|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 5, identity: 0.857

tcaatagcttttaatgtttcgtcttgttccctctt	CRISPR spacer
tcaatagcttttaatgtttcgtcctgctctttttt	Protospacer
***********************.**.**..*.**

53. spacer 3.12|1633596|34|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 5, identity: 0.853

ttgtgctatcgctgactttccaaaagtttctttc	CRISPR spacer
ttgtgctatcactgattttccaaaagttatcttc	Protospacer
**********.****.************ ..***

54. spacer 2.32|1395179|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 6, identity: 0.818

cagtagttttccgttttggtctgaaaacaggag	CRISPR spacer
taacaactttccgttctggtctgaaaacaggag	Protospacer
.*..*..********.*****************

55. spacer 2.32|1395179|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 6, identity: 0.818

cagtagttttccgttttggtctgaaaacaggag	CRISPR spacer
taacaactttccgttctggtctgaaaacaggag	Protospacer
.*..*..********.*****************

56. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_006870 (Bacillus mycoides pDx14.2 plasmid) position: , mismatch: 7, identity: 0.767

aatctctttaacatttatctgacaatcaga	CRISPR spacer
cttaactttaacatttgtctgacaataaaa	Protospacer
  *  ***********.********* *.*

57. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MK215646 (Bacillus phage vB_BthM-Goe5, complete genome) position: , mismatch: 7, identity: 0.767

aatctctttaacatttatctgacaatcaga	CRISPR spacer
aatctctttaacattcatctgtaaaacctc	Protospacer
***************.*****  ** *

58. spacer 1.3|1291469|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to KX827369 (Staphylococcus phage SpT152, complete genome) position: , mismatch: 7, identity: 0.767

aaacggtcggattgaatgaagttatgtata	CRISPR spacer
aaacgatcggattgaatgaagcaattattt	Protospacer
*****.***************. **   *

59. spacer 1.5|1291601|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_009955 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI01, complete sequence) position: , mismatch: 7, identity: 0.767

gtctattaacaaaacgcgagaagagcaact	CRISPR spacer
gccaacataccaaacgcgagaagagcaacg	Protospacer
*.* *.  ** ******************

60. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MN657052 (Psychrobacter sp. strain ANT_P19 plasmid pA19P3, complete sequence) position: , mismatch: 8, identity: 0.733

aatctctttaacatttatctgacaatcaga	CRISPR spacer
tacctctgtaacctttatctgacaatggat	Protospacer
 *.**** **** ************* ..

61. spacer 1.1|1291337|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NC_028659 (Klebsiella phage vB_KpnM_KB57, complete genome) position: , mismatch: 8, identity: 0.733

aatctctttaacatttatctgacaatcaga	CRISPR spacer
caaagctttaacaattatatgacaatcacc	Protospacer
 *   ******** **** *********

62. spacer 2.7|1393652|33|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to MN693159 (Marine virus AFVG_25M303, complete genome) position: , mismatch: 8, identity: 0.758

gttgctactatggcatcagaatatattgttgta	CRISPR spacer
gatacgactatggcatcagattttattgttact	Protospacer
* *.* ************** * *******..

63. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 8, identity: 0.758

taacacgtaacatttttagtgtcatttttttca	CRISPR spacer
gctgaggtgacatttttagtatcatttttttcc	Protospacer
    * **.***********.***********

64. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP053953 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

taacacgt------aacatttttagtgtcatttttttca	CRISPR spacer
------gttgtgaaaacatttttagtgccattttttaca	Protospacer
      **      *************.******** **

65. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP009636 (Bacillus cereus 03BB108 plasmid pBFI_2, complete sequence) position: , mismatch: 8, identity: 0.758

taacacgt------aacatttttagtgtcatttttttca	CRISPR spacer
------gttgtgaaaacatttttagtgccattttttaca	Protospacer
      **      *************.******** **

66. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP053962 (Bacillus cereus strain FDAARGOS_802 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

taacacgt------aacatttttagtgtcatttttttca	CRISPR spacer
------gttgtgaaaacatttttagtgccattttttaca	Protospacer
      **      *************.******** **

67. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP053950 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

taacacgt------aacatttttagtgtcatttttttca	CRISPR spacer
------gttgtgaaaacatttttagtgccattttttaca	Protospacer
      **      *************.******** **

68. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 8, identity: 0.758

taacacgtaacatttttagtgtcatttttttca	CRISPR spacer
tctcctataacatttttattgtcaattttttga	Protospacer
*  * ..*********** ***** ****** *

69. spacer 2.39|1395606|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to MK449000 (Streptococcus phage Javan64, complete genome) position: , mismatch: 8, identity: 0.758

atctgtcaatgggagcagatgacgaaggtttta	CRISPR spacer
acttaaatatgggagcagatgatgatggtttta	Protospacer
*..*.   **************.** *******

70. spacer 3.15|1633793|35|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 8, identity: 0.771

cttctgacaggacttctagcgacaagttattacat	CRISPR spacer
cctcgcttaagacctctagagacaagttattacat	Protospacer
*.**   .*.***.***** ***************

71. spacer 1.3|1291469|30|NZ_CP044493|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013053 (Sinorhizobium americanum CCGM7 plasmid B, complete sequence) position: , mismatch: 9, identity: 0.7

aaacggtcggattgaatgaagttatgtata	CRISPR spacer
gtgcattcggattgattgaagttatgtgcc	Protospacer
. .*. ********* ***********..

72. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 9, identity: 0.727

taacacgtaacatttttagtgtcatttttttca	CRISPR spacer
acatctatatcatttttagtttcatttttttcg	Protospacer
  *. ..** ********** ***********.

73. spacer 2.24|1394691|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_LR135334 (Enterococcus faecium isolate E7471 plasmid 4) position: , mismatch: 9, identity: 0.727

gatatgaattatatcttcttgttccaaatgcca	CRISPR spacer
cttatgaattatttcttcttgttccatagttag	Protospacer
  ********** ************* *  . .

74. spacer 2.24|1394691|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_LR135205 (Enterococcus faecium isolate E7171 plasmid 3) position: , mismatch: 9, identity: 0.727

gatatgaattatatcttcttgttccaaatgcca	CRISPR spacer
cttatgaattatttcttcttgttccatagttag	Protospacer
  ********** ************* *  . .

75. spacer 2.34|1395301|33|NZ_CP044493|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 9, identity: 0.727

tttgaaaatcctgctgtacagtcgttttccgta	CRISPR spacer
ggtaaaaatgctgctggacagtcgttttatgac	Protospacer
  *.***** ****** *********** .*

76. spacer 2.22|1394569|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_LR134422 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 13) position: , mismatch: 10, identity: 0.697

atgaaaattaaaacaggagacatttaattagcg	CRISPR spacer
aaatgaattaaaacatgagacatttgatttata	Protospacer
* . .********** *********.*** ...

77. spacer 2.23|1394630|33|NZ_CP044493|CRISPRCasFinder,CRT matches to NZ_CP020747 (Bacillus mycoides strain Gnyt1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.697

taacacgtaacatttttagtgtcatttttttca	CRISPR spacer
atatttttaacacttttagtgtcacttttttat	Protospacer
  *. . *****.***********.******

78. spacer 3.3|1633001|33|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 10, identity: 0.697

ctttctacctctccttcatattccagccatctt	CRISPR spacer
ccgaagccctctccttgatcttccagccatcaa	Protospacer
*.     ********* ** ***********

79. spacer 3.7|1633263|35|NZ_CP044493|CRT,PILER-CR,CRISPRCasFinder matches to MT197175 (Klebsiella phage VLC5, complete genome) position: , mismatch: 10, identity: 0.714

agcgtgttgattgcaacattcttagctgcgttatt	CRISPR spacer
taagtgttaattggaacattcttagctggtgtagg	Protospacer
 . *****.**** **************   **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

411449 : 420753

Bacillus_virus(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002265670.1\|411449_412799_+	DEAD/DEAH box helicase	A0A1B1IS59	uncultured_Mediterranean_phage	1.8e-47	32.0
WP_002280831.1\|413032_413854_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_002265285.1\|413876_414680_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002267023.1\|414679_415423_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.2e-28	39.6
WP_002267024.1\|415471_415696_+	DUF4059 family protein	NA	NA	NA	NA
WP_019313521.1\|415758_416673_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	3.0e-86	52.6
WP_002267026.1\|417024_418485_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	1.7e-94	39.7
WP_002267027.1\|418481_419306_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	3.5e-73	54.5
WP_002263054.1\|419418_420753_+	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	1.3e-66	34.2

DBSCAN-SWA_2

846863 : 853713

Pneumococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002265143.1\|846863_847352_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.6e-47	57.9
WP_024785258.1\|847364_848081_-	7-carboxy-7-deazaguanine synthase QueE	E7DN68	Pneumococcus_phage	8.2e-63	48.0
WP_002263290.1\|848077_848524_-	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	1.1e-41	60.6
WP_002263291.1\|848523_849177_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	7.7e-60	52.4
WP_002263292.1\|849728_850163_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_151416273.1\|850166_851969_+	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	1.1e-18	30.7
WP_019313596.1\|851958_853713_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.6e-43	28.0

DBSCAN-SWA_3

988849 : 997633

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002264266.1\|988849_990565_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	7.5e-272	82.5
WP_151416298.1\|990695_992441_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.9e-53	29.2
WP_151416299.1\|992437_994171_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.4e-39	26.0
WP_002262260.1\|994180_994795_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.2e-22	37.6
WP_002265988.1\|994796_995774_-	nucleoid-associated protein	NA	NA	NA	NA
WP_151416300.1\|995770_997033_-	serine hydroxymethyltransferase	A0A219YB23	Aeromonas_phage	1.3e-98	52.1
WP_002264270.1\|997042_997633_-	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	1.1e-15	33.2

DBSCAN-SWA_4

1540265 : 1554087

Streptococcus_phage(84.62%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002266825.1\|1540265_1541093_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	7.4e-124	76.9
WP_002264017.1\|1541157_1541781_-	endonuclease III	NA	NA	NA	NA
WP_002268057.1\|1541845_1542199_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.8e-39	66.1
WP_002268058.1\|1542235_1542730_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	7.4e-47	55.7
WP_002291380.1\|1542818_1544000_-	D-3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	1.8e-179	79.3
WP_172964892.1\|1544085_1544640_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.3e-52	65.6
WP_002294716.1\|1544790_1544931_-	hypothetical protein	NA	NA	NA	NA
WP_002285020.1\|1545048_1546140_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.2e-169	79.3
WP_002264023.1\|1546359_1546701_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_151416393.1\|1546716_1547931_-	ammonium transporter	NA	NA	NA	NA
WP_002264025.1\|1548235_1549102_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	73.9
WP_002271433.1\|1549107_1549440_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.1e-29	59.1
WP_002274530.1\|1549432_1550239_-	signal peptidase II	NA	NA	NA	NA
WP_002280200.1\|1550235_1551111_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.9e-78	53.8
WP_002264028.1\|1551123_1551762_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-75	65.1
WP_002264029.1\|1551837_1552497_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.6e-67	60.6
WP_002262679.1\|1552612_1553323_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.8e-14	26.9
WP_002262678.1\|1553322_1554087_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-16	26.4

DBSCAN-SWA_5

1987071 : 1995475

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106006868.1\|1987071_1987662_-	transglycosylase SLT domain-containing protein	Q4Z8Z7	Staphylococcus_phage	7.8e-27	53.8
WP_002262447.1\|1987823_1988690_-	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	1.3e-22	75.7
WP_002262448.1\|1988878_1989673_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_002262449.1\|1989665_1990508_-	energy-coupling factor transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	6.1e-17	23.6
WP_002262450.1\|1990483_1991326_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	1.1e-21	30.0
WP_002267084.1\|1991329_1991872_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_002267085.1\|1991883_1992861_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002264239.1\|1992933_1994226_-	insulinase family protein	A0A0G2Y5U8	Acanthamoeba_polyphaga_mimivirus	7.7e-19	34.7
WP_002279892.1\|1994227_1995475_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.5e-99	45.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP044493

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection